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Sample records for wu lingen chen

  1. KWL Lingen nuclear plant. Technical annual report 2016; KWL Kernkraftwerk Lingen. Technischer Jahresbericht 2016

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2017-07-01

    The technical annual report 2016 for KWL (Lingen nuclear plant) covers the following sections: dismantling project management and operation, monitoring and clearance; waste management, technical qualification, security and safety, central tasks; licensing and supervision procedures, operational data, radiation monitoring, radioactive materials, in-service inspections.

  2. Chen Hengzhe

    DEFF Research Database (Denmark)

    Gimpel, Denise

    Chen Hengzhe has been celebrated as China’s first female professor, first professor of Western history, first person to publish a history of the West that was not a translation into Chinese. She is moreover celebrated as one of the first to write fiction and poetry in the vernacular and to have...... been the first to write children’s literature. In 1914 she was among the first group of women to gain a Boxer Indemnity grant to study in America. The reiteration of these many “firsts” has led to a rather stereotypical portrait of Chen Hengzhe in Chinese sources and, as a result, in most Western...... references to her. To date we have no critical study of her work or activities in Chinese or any other language. Chen Hengzhe’s life and textual production, however, deserve and reward closer scholarly attention. They are not only pertinent to analysis of developments in early twentieth-century China...

  3. Chen Hengzhe

    DEFF Research Database (Denmark)

    Gimpel, Denise

    been the first to write children’s literature. In 1914 she was among the first group of women to gain a Boxer Indemnity grant to study in America. The reiteration of these many “firsts” has led to a rather stereotypical portrait of Chen Hengzhe in Chinese sources and, as a result, in most Western...... references to her. To date we have no critical study of her work or activities in Chinese or any other language. Chen Hengzhe’s life and textual production, however, deserve and reward closer scholarly attention. They are not only pertinent to analysis of developments in early twentieth-century China...

  4. Chen Hengzhe

    DEFF Research Database (Denmark)

    Gimpel, Denise

    Chen Hengzhe has been celebrated as China’s first female professor, first professor of Western history, first person to publish a history of the West that was not a translation into Chinese. She is moreover celebrated as one of the first to write fiction and poetry in the vernacular and to have...

  5. Chen Hengzhe

    DEFF Research Database (Denmark)

    Gimpel, Denise

    Chen Hengzhe has been celebrated as China’s first female professor, first professor of Western history, first person to publish a history of the West that was not a translation into Chinese. She is moreover celebrated as one of the first to write fiction and poetry in the vernacular and to have...... references to her. To date we have no critical study of her work or activities in Chinese or any other language. Chen Hengzhe’s life and textual production, however, deserve and reward closer scholarly attention. They are not only pertinent to analysis of developments in early twentieth-century China......; they speak to important questions in China today. This study, then, is not a biography of a person; it is an attempt to understand the way in which foreign influences (narratives of being, organizing, thinking, writing) seep into a person’s life and work and meld with the “home” influences (narratives...

  6. Chen Hengzhe

    DEFF Research Database (Denmark)

    Gimpel, Denise

    Chen Hengzhe has been celebrated as China’s first female professor, first professor of Western history, first person to publish a history of the West that was not a translation into Chinese. She is moreover celebrated as one of the first to write fiction and poetry in the vernacular and to have......; they speak to important questions in China today. This study, then, is not a biography of a person; it is an attempt to understand the way in which foreign influences (narratives of being, organizing, thinking, writing) seep into a person’s life and work and meld with the “home” influences (narratives...

  7. Chen Li: China's elder psychologist.

    Science.gov (United States)

    Blowers, G H

    1998-01-01

    Chen Li is one of a small group of psychologists in China who trained abroad early in their careers, returned to teach and do research, and continued doing so into later life beyond normal retirement age. His contacts with a number of prominent psychologists in England and Germany in the 1930s, and his inadvertent position at the center of a political row in China in the 1960s, leading to the shutting down of psychology for 10 years, made him historically important. Known for his work in organizational psychology and education, he is a distinguished psychologist and educational leader. Although trained as an experimentalist, he now embraces a broader view of psychology but remains emphatic it should be applied to real-life problems.

  8. [Analysis of professor WU Lianzhong's experience of neck acupoints application].

    Science.gov (United States)

    Peng, Jiandong; Zheng, Hongyan; Wang, Yingshu

    2015-09-01

    Professor WU Lianzhong's experience of neck acupoints application is introduced. The characteristics,locations, acupuncture manipulations ,efficiency and main functions of neck acupoints including Tiandixue (Extra), Jingbixue (Extra), and cervical Jiaji (EX-B 2) are stated. According to the TCM thought of treatment based on syndrome differentiation,WU Lianzhong's special theory of neck acupoints application is explained so as to provide experience for improving acupuncture effects.

  9. [Dialectic research on family lineage of Wu Kun, a Xin'an famous physician].

    Science.gov (United States)

    Zhang, L; Yao, S

    2000-07-01

    The records on the family lineage of a personage in the medical circle should be as accurate as possible. In Textual Research on Xin'an Famous Doctor, it is said that the Xin'an famous physician Wu Kun was the grandson of Wu Znenglun. Through dialectic research, this saying was proved to be untrue. Wu Kun's grandfather is Wu Yuan - chang, who had no direct blood relationship with Wu Zhenglun.

  10. Stability analysis of distributed order fractional chen system.

    Science.gov (United States)

    Aminikhah, H; Refahi Sheikhani, A; Rezazadeh, H

    2013-01-01

    We first investigate sufficient and necessary conditions of stability of nonlinear distributed order fractional system and then we generalize the integer-order Chen system into the distributed order fractional domain. Based on the asymptotic stability theory of nonlinear distributed order fractional systems, the stability of distributed order fractional Chen system is discussed. In addition, we have found that chaos exists in the double fractional order Chen system. Numerical solutions are used to verify the analytical results.

  11. [Textual research on the edition of WU Kun's books].

    Science.gov (United States)

    Wang, Xu-Guang; Lu, Xiang

    2013-03-01

    WU Kun is a famous physician of the Xin'an School. He wrote a 6-volume Yi fang kao (Textual Research on Recipes) in 1584, a 24-volume Wu zhu su wen (Wu's Annotation of Plain Questions) in 1594, a 6-volume Zhen fang liu ji (Six Collections of Acupuncture and Prescription) in 1618 block-printed and funded by CHENG Biao, and a 2-volume Mai yu (Language of Pulse) with writing date unknown. For Yi fang kao, there were 4 editions, including Ming-dynasty block-printed edition, Japanese and Korean block-printed edition, old hand-copied edition and modern printing edition. For Wu zhu su wen, there were 5 editions, Ming-Qing-dynasty block-printed edition, Japanese block-printed edition, old hand-copied edition, photocopy and modern edition. For Zhen fang liu ji, there were Ming-dynasty block-printed edition, hand-copied edition, photocopy and modern edition. Mai yu always was printed together with Yi fang kao, and its editions were same as those of Yi fang kao, except some modern printing edition with Mai yu excluded.

  12. Wu-Ling-San formula prophylaxis against recurrent calcium oxalate ...

    African Journals Online (AJOL)

    WLS formula is a promising adjunct to surgical and medical management of kidney stones. Active therapy with WLS formula has a positive effect on diuresis without leading to electrolyte imbalance. Key words: Calcium oxalate, Urinary Stone, Traditional Chinese Medicine, Wu-Ling-San Formula, Nephrolithiasis.

  13. Comments on “The boundary point method for the calculation of exterior acoustic radiation problem” [S.Y. Zhang, X.Z. Chen, Journal of Sound and Vibration 228(4) (1999) 761 772

    Science.gov (United States)

    Chen, J. T.; Chen, I. L.; Lee, Y. T.

    2008-03-01

    Zhang and Chen [The boundary point method for the calculation of exterior acoustic radiation problem, Journal of Sound and Vibration 228 (1999) 761-772] proposed a boundary point method (BPM) for exterior acoustic problems. The idea is similar to the CHUNKY CHIEF by Wu [A weighted residual formulation for the CHIEF method in acoustic, Journal of Acoustical Society of America 90 (1991) 1608-1614], but Chunky CHIEF provides constraints using null-field equations while the BPM used the CHUNKY BLOCK singularity outside the domain. The mathematical structure is similar to Trefftz method and method of fundamental solutions [J.T. Chen et al., On the equivalence of the Trefftz method and method of fundamental solutions for Laplace and biharmonic equations, Computers & Mathematics with Applications 53 (2007) 851-879], since the interpolation function satisfies the governing equation. Later, Wu commented twice [Sean F. Wu, Comments on "The boundary point method for the calculation of exterior acoustic radiation" (by S.Y. Zhang, X.Z. Chen, Journal of Sound and Vibration 228(4) (1999) 761-772), Journal of Sound and Vibration, 298 (2006) 1173]; Sean F. Wu, Comments on "Reply to the comments on 'The boundary point method for the calculation of exterior acoustic radiation' (by S.Y. Zhang, X.Z. Chen, Journal of Sound and Vibration 228(4) (1999) 761-772)", Journal of Sound and Vibration, 298 (2006) 1176-1177] that the formulation of BPM is wrong and the authors replied also twice [X.Z. Chen, C.X. Bi, Reply to the comments on "The boundary point method for the calculation of exterior acoustic radiation" (by S.Y. Zhang, X.Z. Chen, Journal of Sound and Vibration 228(4) (1999) 761-772), Journal of Sound and Vibration, 298 (2006) 1174-1175; [X.Z. Chen, C.X. Bi, Reply to the comments on "Reply to the comments on 'The boundary point method for the calculation of exterior acoustic radiation' (by S.Y. Zhang, X.Z. Chen, Journal of Sound and Vibration 228(4) (1999) 761-772)", Journal of Sound

  14. Antioxidant activities of seed extracts from Dalbergia odorifera T. Chen

    African Journals Online (AJOL)

    The heartwood or root of Dalbergia odorifera T. Chen is an important traditional Chinese medicine. Antioxidant activities of seed extracts from D. odorifera T. Chen were first investigated in this study. Ethanolic extracts were suspended in distilled water and partitioned successively with petroleum ether, ethyl acetate, ...

  15. Towards a Collective Intelligence: Transmediality and the Wu Ming Project

    Directory of Open Access Journals (Sweden)

    Melina Anne Masterson

    2014-11-01

    Full Text Available Dagli albori della Seconda Repubblica in Italia,  le strategie di dominio sui mass media dell’ex premier Silvio Berlusconi hanno avuto un effetto considerevole sull’immaginario culturale italiano. In un approccio multisensoriale e multimediale alla scrittura, il collettivo Wu Ming mette in questione i paradigmi culturali che negli ultimi venti anni sono diventati egemonici. L’esperienza di un romanzo dei Wu Ming va ben oltre la parola stampata poiché cerca di stimolare tutti i cinque sensi per arricchire il modo in cui il lettore vive quello che c’è sulla pagina, dimostrando esempi chiari della «convergence culture» coniata da Henry Jenkins. Questo saggio esamina l’interazione tra parola e immagine messa in atto dal collettivo tramite il sito Pinterest e illustra come questo aspetto del loro progetto rappresenti un microcosmo di un approccio complessivo alla creazione estetica e alla pratica culturale. Inoltre, questo saggio descrive in che modo il processo collettivo di consumo portato avanti dai Wu Ming contribuisca alla formazione delle «communities of sentiment» di Arjun Appadurai e alla «intelligenza collettiva» di Jenkins. Queste sono formazioni che rivitalizzano il concetto di cultura popolare per la nostra epoca digitale e offrono un’alternativa ad un immaginario culturale italiano sovra-determinato dalle pratiche del Berlusconismo.

  16. Consistent Yokoya-Chen Approximation to Beamstrahlung(LCC-0010)

    Energy Technology Data Exchange (ETDEWEB)

    Peskin, M

    2004-04-22

    I reconsider the Yokoya-Chen approximate evolution equation for beamstrahlung and modify it slightly to generate simple, consistent analytical approximations for the electron and photon energy spectra. I compare these approximations to previous ones, and to simulation data.I reconsider the Yokoya-Chen approximate evolution equation for beamstrahlung and modify it slightly to generate simple, consistent analytical approximations for the electron and photon energy spectra. I compare these approximations to previous ones, and to simulation data.

  17. Multiorgan WU Polyomavirus Infection in Bone Marrow Transplant Recipient.

    Science.gov (United States)

    Siebrasse, Erica A; Nguyen, Nang L; Willby, Melisa J; Erdman, Dean D; Menegus, Marilyn A; Wang, David

    2016-01-01

    WU polyomavirus (WUPyV) was detected in a bone marrow transplant recipient with severe acute respiratory distress syndrome who died in 2001. Crystalline lattices of polyomavirus-like particles were observed in the patient's lung by electron microscopy. WUPyV was detected in the lung and other tissues by real-time quantitative PCR and identified in the lung and trachea by immunohistochemistry. A subset of WUPyV-positive cells in the lung had morphologic features of macrophages. Although the role of WUPyV as a human pathogen remains unclear, these results clearly demonstrate evidence for infection of respiratory tract tissues in this patient.

  18. Chen's attractor exists if Lorenz repulsor exists: The Chen system is a special case of the Lorenz system

    Science.gov (United States)

    Algaba, Antonio; Fernández-Sánchez, Fernando; Merino, Manuel; Rodríguez-Luis, Alejandro J.

    2013-09-01

    In this paper, we show, by means of a linear scaling in time and coordinates, that the Chen system, given by ẋ=a(y-x), ẏ=(c-a)x+cy-xz, ż=-bz+xy, is, generically (c ≠0), a special case of the Lorenz system. First, we infer that it is enough to consider two parameters to study its dynamics. Furthermore, we prove that there exists a homothetic transformation between the Chen and the Lorenz systems and, accordingly, all the dynamical behavior exhibited by the Chen system is present in the Lorenz system (since the former is a special case of the second). We illustrate our results relating Hopf bifurcations, periodic orbits, invariant surfaces, and chaotic attractors of both systems. Since there has been a large literature that has ignored this equivalence, the aim of this paper is to review and clarify this field. Unfortunately, a lot of the previous papers on the Chen system are unnecessary or incorrect.

  19. Topological field theories on manifolds with Wu structures

    Science.gov (United States)

    Monnier, Samuel

    We construct invertible field theories generalizing abelian prequantum spin Chern-Simons theory to manifolds of dimension 4ℓ + 3 endowed with a Wu structure of degree 2ℓ + 2. After analyzing the anomalies of a certain discrete symmetry, we gauge it, producing topological field theories whose path integral reduces to a finite sum, akin to Dijkgraaf-Witten theories. We take a general point of view where the Chern-Simons gauge group and its couplings are encoded in a local system of integral lattices. The Lagrangian of these theories has to be interpreted as a class in a generalized cohomology theory in order to obtain a gauge invariant action. We develop a computationally friendly cochain model for this generalized cohomology and use it in a detailed study of the properties of the Wu Chern-Simons action. In the 3-dimensional spin case, the latter provides a definition of the “fermionic correction” introduced recently in the literature on fermionic symmetry protected topological phases. In order to construct the state space of the gauged theories, we develop an analogue of geometric quantization for finite abelian groups endowed with a skew-symmetric pairing. The physical motivation for this work comes from the fact that in the ℓ = 1 case, the gauged 7-dimensional topological field theories constructed here are essentially the anomaly field theories of the 6-dimensional conformal field theories with (2, 0) supersymmetry, as will be discussed elsewhere.

  20. Discussion on manufacturing techniques of Chen Zhang Pot

    Directory of Open Access Journals (Sweden)

    Fan Taofeng

    2013-01-01

    Full Text Available The Chen Zhang Pot, made in the late Warring States period is an openwork bronze pot with gold and silver inlay. It was identified as a first-class historical relic of the nation by the State Administration of Cultural Heritage in 2001. To explore its manufacturing techniques, XRF, CT and X-Ray photograph microscopic observation were adopted for the non-destructive examination of the Chen Zhang Pot. The analysis data show that many parts of the Chen Zhang Pot were cast separately, and then assembled. It also shows that the composition proportion of each part of the Chen Zhang Pot is different; and the bronze color, hardness and tensile strength are different for each alloy proportion. A variety of decoration techniques were adopted in the manufacturing process, which make the color more diverse and gorgeous. The openwork decoration is the most complex part of the pot, and the gold and silver decoration technique also represents the high level manufacturing technology in the Warring States period. In summary, the Chen Zhang Pot is a unique art treasure, and as a specimen it allows us to study the bronze casting technology in the Warring States period.

  1. The age grading and the Chen-Ruan cup product

    DEFF Research Database (Denmark)

    A. Hepworth, Richard

    2010-01-01

    We prove that the obstruction bundle used to define the cup-product in Chen-Ruan cohomology is determined by the so-called `age grading' or `degree-shifting numbers'. Indeed, the obstruction bundle can be directly computed using the age grading. We obtain a Kunneth Theorem for Chen-Ruan cohomology...... as a direct consequence of an elementary property of the age grading, and explain how several other results - including associativity of the cup-product - can be proved in a similar way....

  2. Fuzzy Sliding Mode Control for Hyper Chaotic Chen System

    Directory of Open Access Journals (Sweden)

    SARAILOO, M.

    2012-02-01

    Full Text Available In this paper, a fuzzy sliding mode control method is proposed for stabilizing hyper chaotic Chen system. The main objective of the control scheme is to stabilize unstable equilibrium point of the system by controlling the states of the system so that they converge to a pre-defined sliding surface and remain on it. A fuzzy control technique is also utilized in order to overcome the main disadvantage of sliding mode control methods, i.e. chattering problem. It is shown that the equilibrium point of the system is stabilized by using the proposed method. A stability analysis is also performed to prove that the states of the system converge to the sliding surface and remain on it. Simulations show that the control method can be effectively applied to Chen system when it performs hyper chaotic behavior.

  3. Governing Civil Service Pay in China, by Alfred M. Wu. Copenhagen: NIAS Press, 2014. xvi+236 pp

    DEFF Research Database (Denmark)

    Brødsgaard, Kjeld Erik

    2016-01-01

    Book review of: Governing Civil Service Pay in China by Alfred M. Wu. Copenhagen: NIAS Press, 2014.......Book review of: Governing Civil Service Pay in China by Alfred M. Wu. Copenhagen: NIAS Press, 2014....

  4. Chien-Shiung Wu: An Icon of Physicist and Woman Scientist in China

    Science.gov (United States)

    Zhu, Yuelin

    2014-03-01

    Chien-Shiung Wu, the first female president of APS, is a well-known figure in China, a figure who serves as an inspiration for youths, especially young women, to study science and particularly physics. In this presentation, a historical perspective will be used to show how such an icon was formed. Born in 1912, the year of the Republic Revolution, Wu was in the first generation of physicists in China and her college mentor was a student of Marie Curie. When Wu came to the U.S. for graduate studies in the 1930s, it was a ``golden age'' for nuclear physics, and the invention of the cyclotron by E. O. Lawrence put UC Berkeley at the frontier. Wu was trained there, with Lawrence as her advisor, and later became an expert in Beta-decay. In 1956, Wu conceived and initiated the experiment of Cobalt-60, which, together with other two experiments, eventually proved the asymmetry of parity in weak-interactions, a hypothesis proposed by T. D. Lee and C. N. Yang. The importance of the experiment gained Wu an enormous reputation which spread even to China, when this was a period of hostility in Sino-American relations, and near total isolation due to the Cold-War. Wu was the daughter of a revolutionary, and an activist in college in patriotic student movements, and she combined this background with her scientific career as the way of ``Saving China with Science,'' a common belief reflecting the Zeitgeist of her time. Although she spent most of her life in the U.S., Wu never wavered in her love for or loyalty to her motherland. Her patriotism, as well as her scientific achievement, made Wu a legend in China, being called ``the Chinese Madam Curie.'' Even during the Cultural Revolution, a novel supposedly taking Wu as the original model was very popular in underground circles, widely spread by hand-written-copies. From 1979-1988, the CUSPEA program enrolled hundreds of China's best graduate students into physics departments in American universities. Although Wu herself was not

  5. Analysing the Wu metric on a class of eggs in Cn – II

    Indian Academy of Sciences (India)

    Indian Acad. Sci. (Math. Sci.) Vol. 127, No. 3, June 2017, pp. 463–470. DOI 10.1007/s12044-017-0330-y. Analysing the Wu metric on a class of eggs in Cn – II ... In general, the Wu met- ric may fail to be upper ... metric on E2m. Note that E2m is a balanced pseudoconvex domain in Cn and hence the. Kobayashi metric at the ...

  6. Beschichtung hochwertiger Karosserieoberflächen mit Pulver-Slurry

    OpenAIRE

    Weckerle, Gero

    2003-01-01

    Die Beschichtung von Karosserieaußenflächen erfolgt heute vorwiegend durch elektrostatisch unterstützte Hochrotationszerstäuber (ESTA-HR) an Lackierautomaten, die zunehmend durch Lackierroboter ersetzt werden. Dieser technologische Wandel basiert auf den Qualitäts- und Kostenvorteilen, die sich beim Einsatz der Roboter ergeben. So kann beispielsweise durch die höhere Flexibilität der Bewegung die Zahl der erforderlichen Zerstäuber pro Lackierzone deutlich reduziert werden. Um dennoch die gefo...

  7. Lattice models and integrability: a special issue in honour of F Y Wu

    Science.gov (United States)

    Guttmann, A. J.; Jacobsen, J. L.

    2012-12-01

    Fa Yueh (Fred) Wu was born on 5 January 1932 in Nanking (now known as Nanjing), China, the capital of the Nationalist government. Wu began kindergarten in 1937 in a comfortable setting, as his father held a relatively high government position. But the Sino-Japanese war broke out in July 1937, and Nanking fell to Japanese hands in November. Fleeing the Japanese, his parents brought Wu to their hometown in Hunan, and then to the war capital Chungking (now Chongqing) in 1938, where they lived for eight years until the end of the war. Around that time the Japanese began bombing Chungking, and Wu's childhood memories were dominated by air raids, bombings and burning not dissimilar to those experienced by Londoners during the war. At times the air raids lasted for days disrupting everyday lives in Chungking, including Wu's schooling. One day during a fierce bombing raid, a bomb fell in their garden reducing a pavilion and the surrounding pond to a huge crater; another bomb fell just a few metres from the tunnel where his family took shelter, almost sealing the only entrance. The family moved the very next day to the countryside. As a result of the war, Wu attended seven schools before finishing his primary education. Fortunately, by the time he entered junior high school in 1943, the Japanese forces were on the wane and Wu entered the elite middle school, Nankai. His early academic performance in Nankai seemed to him mediocre, but he nevertheless impressed his geometry teacher by showing bursts of talent. With hindsight, this early interest in geometry may have led to his later insights in graphical analyses of statistical systems. The family returned to Nanking in 1946 after the Victory over Japan Day. By this time his father had become elected to the Legislative Yuan, the equivalent of the US Senate. Wu entered high school in Nanking in 1946. Since he came from an elite school in Chungking, he excelled in most of his classes, especially mathematics. Notwithstanding his

  8. Ray Wu as Fifth Business: Deconstructing collective memory in the history of DNA sequencing.

    Science.gov (United States)

    Onaga, Lisa A

    2014-06-01

    The concept of 'Fifth Business' is used to analyze a minority standpoint and bring serious attention to the role of scientists who play a galvanizing role in a science but for multiple reasons appear less prominently in more common recounts of any particular development. Biochemist Ray Wu (1928-2008) published a DNA sequencing experiment in March 1970 using DNA polymerase catalysis and specific nucleotide labeling, both of which are foundational to general sequencing methods today. The scant mention of Wu's work from textbooks, research articles, and other accounts of DNA sequencing calls into question how scientific collective memory forms. This alternative history seeks to understand why a key figure in nucleic acid sequence analysis has remained less visibly connected or peripheral to solidifying narratives about the history of DNA sequencing. The study resists predictable dismissals of Wu's work in order to seriously examine the formation of his nucleic acid sequence analysis research program and how he shared his knowledge of sequencing during a period of rapid advancement in the field. An analysis of Wu's work on sequencing the cohesive ends of lambda bacteriophage in the 1960s and 1970s exemplifies how a variety of individuals and groups attempted to develop protocol for sequencing the order of nucleotide base pairs comprising DNA. This historical examination of the sociality of scientific research suggests a way to understand how Wu and others contributed to the very collective memory of DNA sequencing that Wu eventually tried to repair. The study of Wu, who was a Chinese immigrant to the United States, provides a foundation for further critical scholarship on the heterogeneous histories of Asian American bioscientists, the sociality of their scientific works, and how the resulting knowledge produced is preserved, if not evenly, in a scientific field's collective memory. Copyright © 2014 Elsevier Ltd. All rights reserved.

  9. The Hintermann-Merlini-Baxter-Wu and the infinite-coupling-limit Ashkin-Teller models

    Energy Technology Data Exchange (ETDEWEB)

    Huang Yuan, E-mail: huangy22@mail.ustc.edu.cn [Hefei National Laboratory for Physical Sciences at Microscale and Department of Modern Physics, University of Science and Technology of China, Hefei, Anhui 230026 (China); Deng Youjin, E-mail: yjdeng@ustc.edu.cn [Hefei National Laboratory for Physical Sciences at Microscale and Department of Modern Physics, University of Science and Technology of China, Hefei, Anhui 230026 (China); Jacobsen, Jesper Lykke, E-mail: jacobsen@lpt.ens.fr [Laboratoire de Physique Theorique, Ecole Normale Superieure, 24 rue Lhomond, 75231 Paris (France); Universite Pierre et Marie Curie, 4 place Jussieu, 75252 Paris (France); Salas, Jesus, E-mail: jsalas@math.uc3m.es [Grupo de Modelizacion, Simulacion Numerica y Matematica Industrial, Universidad Carlos III de Madrid, Avda. de la Universidad 30, 28911 Leganes (Spain); Grupo de Teorias de Campos y Fisica Estadistica, Instituto Gregorio Millan, Universidad Carlos III de Madrid, Unidad asociada al IEM-CSIC, Madrid (Spain)

    2013-03-11

    We show how the Hintermann-Merlini-Baxter-Wu model (which is a generalization of the well-known Baxter-Wu model to a general Eulerian triangulation) can be mapped onto a particular infinite-coupling-limit of the Ashkin-Teller model. We work out some mappings among these models, also including the standard and mixed Ashkin-Teller models. Finally, we compute the phase diagram of the infinite-coupling-limit Ashkin-Teller model on the square, triangular, hexagonal, and kagome lattices.

  10. How Memory Is Tested Influences What Is Measured: Reply to Wyble and Chen (2017)

    Science.gov (United States)

    Swallow, Khena M.; Jiang, Yuhong V.; Tan, Deborah H.

    2017-01-01

    In this response to Wyble and Chen's (2017) commentary on attribute amnesia, we hope to achieve several goals. First, we clarify how our view diverges from that described by Wyble and Chen. We argue that because the surprise memory test is disruptive, it is an insensitive tool for measuring the persistence of recently attended target attributes in…

  11. Analysing the Wu metric on a class of eggs in Cn–I

    Indian Academy of Sciences (India)

    ∣ z 1 ∣ 2 m + ∣ z 2 ∣ 2 + ⋯ + ∣ z n − 1 ∣ 2 + ∣ z n ∣ 2 < 1 } , where m ≥ 1 / 2 , m ≠ 1 . The Wu metric is shown to be real analytic everywhere except on a lower dimensional subvariety where it fails to be C 2 -smooth. Overall however, the ...

  12. Thinking of the safety application of TCM By You Gu Wu Yun , A ...

    African Journals Online (AJOL)

    Background: You Gu Wu Yun (有故无殒), a Chinese ancient medicine application principle, has played an important role in Traditional Chinese Medicine (TCM) clinical practice so far. Materials and Methods: It emphasized that disease, medicine and treatment method were interconnecting and the relationship among these ...

  13. WU Polyomavirus in Respiratory Epithelial Cells from Lung Transplant Patient with Job Syndrome

    OpenAIRE

    Siebrasse, Erica A.; Pastrana, Diana V.; Nguyen, Nang L.; Wang, Annie; Roth, Mark J.; Holland, Steven M.; Freeman, Alexandra F.; McDyer, John; Buck, Christopher B.; Wang, David,

    2015-01-01

    We detected WU polyomavirus (WUPyV) in a bronchoalveolar lavage sample from lungs transplanted into a recipient with Job syndrome by using immunoassays specific for the WUPyV viral protein 1. Co-staining for an epithelial cell marker identified most WUPyV viral protein 1?positive cells as respiratory epithelial cells.

  14. Strength-based Supervision: Frameworks, Current Practice, and Future Directions A Wu-wei Method.

    Science.gov (United States)

    Edwards, Jeffrey K.; Chen, Mei-Whei

    1999-01-01

    Discusses a method of counseling supervision similar to the wu-wei practice in Zen and Taoism. Suggests that this strength-based method and an understanding of isomorphy in supervisory relationships are the preferred practice for the supervision of family counselors. States that this model of supervision potentiates the person-of-the-counselor.…

  15. Phase transitions in self-dual generalizations of the Baxter-Wu model

    NARCIS (Netherlands)

    Deng, Y.; Guo, W.; Heringa, J.R.; Blöte, H.W.J.; Nienhuis, B.

    2010-01-01

    We study two types of generalized Baxter-Wu models, by means of transfer-matrix and Monte Carlo techniques. The first generalization allows for different couplings in the up- and down-triangles, and the second generalization is to a q-state spin model with three-spin interactions. Both

  16. Review of the genus Neotetricodes Zhang et Chen (Hemiptera: Fulgoromorpha: Issidae) with description of two new species.

    Science.gov (United States)

    Chang, Zhi-Min; Yang, Lin; Zhang, Zheng-Guang; Chen, Xiang-Sheng

    2015-12-11

    Two new species of the issid genus Neotetricodes Zhang et Chen (Hemiptera: Fulgoromorpha: Issidae): Neotetricodes longispinus Chang et Chen sp. nov. (China: Yunnan) and Neotetricodes xiphoideus Chang et Chen sp. nov. (China: Yunnan) are described and illustrated. The generic characteristic is redefined. A checklist and key to the species of the genus are provided. The female genitalia of the genus are firstly described.

  17. Sociology in Times of Crisis: Chen Da, National Salvation and the Indigenization of Knowledge

    Directory of Open Access Journals (Sweden)

    Ana Maria Candela

    2015-08-01

    Full Text Available Chen Da was one of the foremost sociologists of China from the 1920s to the 1940s. His intellectual habitus took shape from the long crisis that defined Chinese intellectual life from the mid-19th to mid-20th centuries, a period of continuous imperial assault on Chinese sovereignty. As China integrated into the capitalist world-system, neo-Confucian structures of knowledge came into question. Intellectuals took up sociology to guide China’s transition from an empire to a nation-state. Through his studies on labor, migration, and population, Chen Da contributed to the institutionalization of sociology in China. Chen sought to craft a theory of Chinese development that followed universal trajectories of progress but was also attuned to the complexity of Chinese society on the ground. Through his efforts to indigenize sociology, Chen developed a non-Marxist historical materialism, a deterritorialized and pluralistic conceptualization of China as a nation, and a theory of eugenic transformation centered on the concept of “mode of living.” The questions which Chen Da confronted are emblematic of the predicament faced by Chinese social scientists today, who again struggle with the dynamics of a deterritorialzied “Greater China,” rising social fragmentation, and refigured eugenic discourses and policies that aim to craft the Chinese people into ideal national subjects fit for post-socialist development.

  18. Ignition delay time correlation of fuel blends based on Livengood-Wu description

    KAUST Repository

    Khaled, Fathi

    2017-08-17

    In this work, a universal methodology for ignition delay time (IDT) correlation of multicomponent fuel mixtures is reported. The method is applicable over wide ranges of temperatures, pressures, and equivalence ratios. n-Heptane, iso-octane, toluene, ethanol and their blends are investigated in this study because of their relevance to gasoline surrogate formulation. The proposed methodology combines benefits from the Livengood-Wu integral, the cool flame characteristics and the Arrhenius behavior of the high-temperature ignition delay time to suggest a simple and comprehensive formulation for correlating the ignition delay times of pure components and blends. The IDTs of fuel blends usually have complex dependences on temperature, pressure, equivalence ratio and composition of the blend. The Livengood-Wu integral is applied here to relate the NTC region and the cool flame phenomenon. The integral is further extended to obtain a relation between the IDTs of fuel blends and pure components. Ignition delay times calculated using the proposed methodology are in excellent agreement with those simulated using a detailed chemical kinetic model for n-heptane, iso-octane, toluene, ethanol and blends of these components. Finally, very good agreement is also observed for combustion phasing in homogeneous charge compression ignition (HCCI) predictions between simulations performed with detailed chemistry and calculations using the developed ignition delay correlation.

  19. Phylogeography of Sophora moorcroftiana Supports Wu's Hypothesis on the Origin of Tibetan Alpine Flora.

    Science.gov (United States)

    Cheng, Shanmei; Qiong, La; Lu, Fan; Yonezawa, Takahiro; Yin, Ganqiang; Song, Zhiping; Wang, Yuguo; Yang, Ji; Zhang, Wenju

    2017-06-01

    Wu hypothesized that the Tibetan flora originated mostly from the paleotropical Tertiary flora in the Hengduan Mountains by adapting to the cold and arid environments associated with the strong uplift of the Qinghai-Tibet Plateau (QTP). Here, we combine the phylogeographic history of Sophora moorcroftiana with that of Sophora davidii to explore the speciation of S. moorcroftiana to test this hypothesis. We collected 151 individuals from 17 populations and sequenced 2 chloroplast fragments and the internal transcribed spacer of rDNA. Five chlorotypes and 9 ribotypes were detected but no significant phylogeographic structure was revealed. The integrated results of phylogeographic studies of these 2 species clearly support the progenitor-derivative relationship between them. We infer that the western peripheral population of S. davidii migrated westwards from the Hengduan Mountains to the middle reaches of the Yarlung Zangbo River and differentiated from its ancestor in the process of adaptation to increasingly cold and arid environments with the uplift of the QTP and finally evolved into S. moorcroftiana during the Late Pliocene. In addition, our findings shed light on the idea that natural selection, as imposed by climate differentiation (especially mean diurnal range and precipitation seasonality), directly drove this peripatric speciation event after geographic isolation. The speciation of S. moorcroftiana is a strong case supporting Wu's hypothesis about the origin of Tibet's flora. © The American Genetic Association 2017. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  20. Gene identification and functional analysis of methylcitrate synthase in citric acid-producing Aspergillus niger WU-2223L.

    Science.gov (United States)

    Kobayashi, Keiichi; Hattori, Takasumi; Honda, Yuki; Kirimura, Kohtaro

    2013-01-01

    Methylcitrate synthase (EC 2.3.3.5; MCS) is a key enzyme of the methylcitric acid cycle localized in the mitochondria of eukaryotic cells and related to propionic acid metabolism. In this study, cloning of the gene mcsA encoding MCS and heterologous expression of it in Escherichia coli were performed for functional analysis of the MCS of citric acid-producing Aspergillus niger WU-2223L. Only one copy of mcsA (1,495 bp) exists in the A. niger WU-2223L chromosome. It encodes a 51-kDa polypeptide consisting of 465 amino acids containing mitochondrial targeting signal peptides. Purified recombinant MCS showed not only MCS activity (27.6 U/mg) but also citrate synthase (EC 2.3.3.1; CS) activity (26.8 U/mg). For functional analysis of MCS, mcsA disruptant strain DMCS-1, derived from A. niger WU-2223L, was constructed. Although A. niger WU-2223L showed growth on propionate as sole carbon source, DMCS-1 showed no growth. These results suggest that MCS is an essential enzyme in propionic acid metabolism, and that the methylcitric acid cycle operates functionally in A. niger WU-2223L. To determine whether MCS makes a contribution to citric acid production, citric acid production tests on DMCS-1 were performed. The amount of citric acid produced from glucose consumed by DMCS-1 in citric acid production medium over 12 d of cultivation was on the same level to that by WU-2223L. Thus it was found that MCS made no contribution to citric acid production from glucose in A. niger WU-2223L, although MCS showed CS activity.

  1. Secure Communication Based on Hyperchaotic Chen System with Time-Delay

    Science.gov (United States)

    Ren, Hai-Peng; Bai, Chao; Huang, Zhan-Zhan; Grebogi, Celso

    An experimental secure communication method based on the Chen system with time-delay is being proposed in this paper. The Chen system with time-delay is an infinite-dimensional system having more than one positive Lyapunov exponent. The message to be transmitted is encrypted using an hyperchaotic signal generated by the Chen system with time-delay and multishift cipher function. This encryption makes difficult for an eavesdropper to reconstruct the attractor by using time-delay embedding techniques, return map reconstruction, or spectral analysis, consequently, improving the security. Simulations and experiments on TI TMS320C6713 Digital Signal Processor (DSP) show improved resilience against attack and the feasibility of the proposed scheme.

  2. Chen Ning Yang’s New Contributions After He Returned to Where He Started

    Science.gov (United States)

    Zhu, Bang-Fen

    2018-01-01

    Chen Ning Yang returned to Tsinghua University as a full professor in 2003. Regarding the fact that very few people know what Professor Yang has contributed to science and to China after his return, in this article new contributions of Chen Ning Yang are introduced as far as the author knows, including his leading role in China’s sciences, the research in statistical physics, the role in cultivating gifted students, his research in history of science, and all other aspects relating to China’s developments.

  3. Variability of OI 090.4 ShaoMing Hu , Xu Chen & DiFu Guo

    Indian Academy of Sciences (India)

    2009-12-20

    Dec 20, 2009 ... ShaoMing Hu. ∗. , Xu Chen & DiFu Guo. School of Space Science and Physics, Shandong University, Weihai,. 180 Cultural West Road, Shandong 264209, China. ∗ e-mail: husm@sdu.edu.cn. Abstract. OI 090.4 was monitored on 21 nights from 2006 to 2012 for studying the variability. Strong variations ...

  4. TEST OF THE CHEN-ROLL-ROSS MACROECONOMIC FACTOR MODEL: EVIDENCE FROM CROATIAN STOCK MARKET

    Directory of Open Access Journals (Sweden)

    Denis Dolinar

    2015-12-01

    Full Text Available This paper empirically examines the well-known Chen-Roll-Ross model on the Croatian stock market. Modifications of definitions of the Chen-Roll-Ross model variables showed as necessary because of doubtful availability and quality of input data needed. Namely, some macroeconomic and market variables are not available in the originally defined form or do not exist. In that sense this paper gives some alternative definitions for some model variables. Also, in order to improve statistical analysis, in this paper we have modified Fama-MacBeth technique in the way that second-pass regression was substituted with panel regression analysis. Based on the two-pass regression analysis of returns of 34 Croatian stocks on 4 macroeconomic variables during the seven-and-half-year observation period the following conclusion is made. In contrast to the results of Chen, Roll and Ross (1986 for the U.S. stock market, their model is not successful when describing a risk-return relation of Croatian stocks. Nevertheless, one observed version of the Chen-RollRoss model showed certain statistical significance. Namely, two risk factors in that version of the model were statistically significant: default premium, measured as risk premium for the corporate short-term bank loan financing, and term structure premium, measured on short-run basis.

  5. Memoria, trauma e mitopoiesi: Lawrence d'Arabia e Stella del mattino di Wu Ming 4

    Directory of Open Access Journals (Sweden)

    Emanuela Piga

    2011-11-01

    Full Text Available This article reconsiders the narrative construnction of the historical novel in the light of recent critical debates. Bearing in mind the overarching theme of the hybridization of the historiographic and literary genres, the article examines in detail Wu Ming 4’s solo novel, Stella del mattino (2008. In this work, the rewriting of real, once existing historical characters follows a thread of verisimilitude against the backdrop of meticulously reconstructed historical scenarios. By focusing on the use of history, allegory and myth in the novel, the aim of this study is to examine the narration of the overcoming of Trauma of the First World War through the therapeutic value of writing. In so doing, emphasis is given to passages in which the reader is able to grasp, between  the scattered fragments of history, moments of the utopian impetus, thanks to the narration of communal moments of being and everyday life practices.

  6. A Response to Professor Wu Zongjie's "Interpretation, Autonomy, and Transformation: Chinese Pedagogic Discourse in a Cross-Cultural Perspective"

    Science.gov (United States)

    Curran, Thomas D.

    2014-01-01

    In response to an essay by Prof Wu Zongjie that was published in the "Journal of Curriculum Studies" [43(5), (2011), 569-590], I argue that, despite dramatic changes that have taken place in the language of Chinese academic discourse and pedagogy, evidence derived from the fields of psychology and the history of Chinese educational…

  7. 31 july 2014 - H. WU Ambassador Permanent Representative of the People's Republic of China to the United Nations

    CERN Multimedia

    Egli, Laurent

    2014-01-01

    His Excellency Mr Hailong WU Ambassador Permanent Representative of the People's Republic of China to the United Nations Office at Geneva and other international organizations in Switzerland visiting the ATLAS cavern with ATLAS Spokesperson D. Charlton and the LHC tunnel at Point 1 with Technology Department, Vacuum, Surfaces and Coatings Group P. Cruikshank.

  8. Self-Representation and Cultural Expectations: Yogi Chen and Religious Practices of Life-Writing

    Directory of Open Access Journals (Sweden)

    Richard K. Payne

    2016-03-01

    Full Text Available Explores the differences in self-representation as found in the autobiographical writings of Yogi Chen, Billy Graham, and the Dalai Lama. While the latter two are widely recognized in American popular religious culture, the former is virtually invisible outside the immigrant Chinese American community. This invisibility is consistent with fact that the religious praxes of immigrant communities remain largely under-studied. However, one additional factor appears to be the mismatch between the expectations of the dominant religious culture and the immigrant culture in terms of the ways in which religious leaders represent themselves. Both Billy Graham and the Dalai Lama present themselves in very humble terms, consistent with the expectations of the Pietist background to American popular religion. Yogi Chen on the contrary tends toward a self-aggrandizing style, which although consistent with the competitive nature of premodern Tibetan religious culture is not congruent with the expectations of American popular religion.

  9. UPLC-QTOF-MS with chemical profiling approach for rapidly evaluating chemical consistency between traditional and dispensing granule decoctions of Tao-Hong-Si-Wu decoction

    Directory of Open Access Journals (Sweden)

    Shang Erxin

    2012-11-01

    Full Text Available Abstract Background In the present study, chemical consistency between traditional and dispensing granule decoctions of Tao-Hong-Si-Wu decoction was rapidly evaluated by UPLC-QTOF-MS coupled with the MarkerLynx software. Two different kinds of decoctions, namely traditional decoction: water extract of mixed six constituent herbs of Tao-Hong-Si-Wu decoction, and dispensing granules decoction: mixed water extract of each individual herbs of Tao-Hong-Si-Wu decoction, were prepared. Results Chemical difference was found between traditional and dispensing granule decoctions, and albiflorin, paeoniflorin, gallic acid, amygdalin, and hydroxysafflor yellow A were identified as the significantly changed components during decocting Tao-Hong-Si-Wu decoction. All the peaks of mass spectrum from Tao-Hong-Si-Wu decoction and each herb were extracted and integration by using QuanLynx™. And the optimized data was used for linear regression analysis. The contribution of each herb in Tao-Hong-Si-Wu decoction, and the optimal compatibility proportion of dispensing granule decoction were derived from the linear regression equation. Conclusions The optimal dosage proportionality of Tao-Hong-Si-Wu dispensing granule decoction was obtained as 2.5:0.2:1:0.5:0.6:0.1 (DG : CX : BS : SD : TR : HH, which guided better clinic application of Tao-Hong-Si-Wu decoction as dispensing granule decoctions usage, and it also provided some experimental data to reveal the compatibility rule of the relative TCM formulae.

  10. Functional Integral Approach to Parisi-Wu Stochastic Quantization and Related Problems.

    Science.gov (United States)

    Gozzi, Ennio

    A path-integral formulation is given of the Parisi -Wu method of stochastic quantization. The connection between the Langevin and Fokker-Planck equations is rederived in functional form bringing to light new aspects of these equations. The relation between this functional method and the recent approach by De-Alfaro-Fubini-Furlan is clarified. In particular we present the non-local transformation that connects the two formulations. In this dissertation we also investigate the hidden supersymmetry recently discovered by Parisi and Sourlas in Langevin processes. The Kelvin relations, for diffusion processes out of equilibrium, are shown to be a necessary and sufficient condition to have supersymmetry. This proves that this symmetry is a manifestation, at the path-integral level, of the Onsager principle of microreversibility present in the stochastic process. We analyze, in particular, the interesting interplay between forward and backward Fokker-Planck dynamics and, as an application, we rederive the fluctuation-dissipation theorem as a Ward-identity of this supersymmetry.

  11. Upper respiratory tract tumors in Cpb:WU (Wistar random) rats.

    Science.gov (United States)

    Feron, V J; Woutersen, R A; van Garderen-Hoetmer, A; Dreef-van der Meulen, H C

    1990-01-01

    A survey is given of upper respiratory tract tumors in Cpb:WU (Wistar random) rats. Data were collected from ten 24- to 30-month toxicity/carcinogenicity studies and from one 12-month study. Nasal tumors may lead to dyspnea, mouth breathing, and nasal discharge. These clinical signs mainly occurred in rats bearing squamous cell carcinomas. The large nasal tumors were often osteolytic, they invaded the subcutis over the premaxilla, resulting in swellings on the back of the nose, and extended into the brain. The incidence of nasal tumors in untreated male controls was 1.1% (7/661), the tumors invariably being squamous cell carcinomas. There were no nasal tumors found in untreated female controls. The type of compound-induced nasal tumor most frequently observed was adenocarcinoma (of the olfactory epithelium) followed, in order of decreasing incidence, by squamous cell carcinoma, carcinoma in situ, polypoid adenoma, Schwannoma, and carcinosarcoma. It was proposed that adenocarcinomas of the olfactory epithelium should be classified as neuroepitheliomas. It was also suggested that squamous cell carcinomas, seen in association with necrotizing inflammation of an incisor tooth, should be considered as part of the malocclusion syndrome. No spontaneous tracheal tumors were observed, and only one out of 422 untreated female controls (0.2%) was seen to have a laryngeal tumor, an adenoma. Induced laryngeal tumors included carcinoma in situ, squamous cell carcinoma, and adenocarcinoma. Squamous cell carcinoma was the only type of treatment-related tracheal tumor found. The incidences of induced laryngeal and tracheal tumors were very low, and in no case were these tumors statistically significantly different from the respective incidences in controls. Images PLATE 1. PLATE 2. PLATE 3. PLATE 4. PLATE 5. PLATE 6. PLATE 7. PLATE 8. PLATE 9. PLATE 10. PLATE 11. PLATE 12. PLATE 13. PLATE 14. PLATE 15. PMID:2384064

  12. No evidence for WU polyomavirus infection in chronic obstructive pulmonary disease

    Directory of Open Access Journals (Sweden)

    Ringshausen Felix C

    2009-08-01

    Full Text Available Abstract Human polyomaviruses are known to cause persistent or latent infections, which are reactivated under immunosuppression. Polyomaviruses have been found to immortalize cell lines and to possess oncogenic properties. Moreover, the recently discovered Merkel cell polyomavirus shows a strong association with human Merkel cell carcinomas. Another novel human polyomavirus, WU polyomavirus (WUPyV, has been identified in respiratory specimens from patients with acute respiratory tract infections (ARTI. WUPyV has been proposed to be a pathogen in ARTI in early life and immunocompromised individuals, but so far its role as a causative agent of respiratory disease remains controversial. The objective of our study was to determine the prevalence of WUPyV infections in adult hospitalized patients with acute exacerbation of chronic obstructive pulmonary disease (COPD and to establish its potential clinical relevance by comparison to patients with stable COPD hospitalized for other reasons than acute exacerbation of COPD (AE-COPD. A total of 378 respiratory specimens, each 189 induced sputum and nasal lavage samples from 189 patients, who had been recruited in a prospective 2:1 ratio case-control set-up between 1999 and 2003, were evaluated for the presence of WUPyV DNA by real-time PCR. In the present study we could not detect WUPyV DNA in 378 respiratory specimens from 189 adult hospitalized patients with AE-COPD and stable COPD in four consecutive years. Persistence of viral replication or reactivation of latent WUPyV infection did not occur. WUPyV may not play a major role in adult immunocompetent patients with AE-COPD and stable COPD.

  13. KI and WU Polyomaviruses and CD4+ Cell Counts in HIV-1–infected Patients, Italy

    Science.gov (United States)

    Babakir-Mina, Muhammed; Ciccozzi, Massimo; Farchi, Francesca; Bergallo, Massimiliano; Cavallo, Rossana; Adorno, Gaspare; Perno, Carlo Federico

    2010-01-01

    To investigate an association between KI and WU polyomavirus (KIPyV and WUPyV) infections and CD4+ cell counts, we tested HIV-1–positive patients and blood donors. No association was found between cell counts and virus infections in HIV-1–positive patients. Frequency of KIPyV infection was similar for both groups. WUPyV was more frequent in HIV-1–positive patients. PMID:20735940

  14. PLE-wu, a new member of piggyBac transposon family from insect, is active in mammalian cells.

    Science.gov (United States)

    Wu, Chunxiao; Wang, Shu

    2014-10-01

    piggyBac, a highly active transposon in insect and mammalian cells, is a very useful tool in genome manipulation. A new piggyBac-like element (PLE), named PLE-wu, was identified from a mutant baculovirus cultured in sf9 insect cells. This new transposon is 2931 bp in length and encodes two active forms of transposase, a 708-amino acid-long transposase and a short 576-residue-long transposase translated from a downstream in-frame initiation codon. PLE-wu has asymmetric terminal structures, containing 6-bp inverted terminal repeats, 32-bp imperfect inverted and direct sub-terminal repeats. Similar to piggyBac, PLE-wu exhibits traceless excision activity in both insect and mammalian cells, restoring the original TTAA target sequence upon excision. It also retains the insertion activity in mammalian cells with a plasmid to chromosome transposition rate about 10-fold higher than random integration. Plasmid rescue assays revealed that the TTAA target sequence was duplicated at the junctions of the insertion site. Deletion of the terminal sequences including the sub-terminal repeats decreased the transposition activity of the 708-residue-long transposase, while the transposition activity of the short form of transposase was not affected. With its low sequence similarity to piggyBac, PLE-wu will contribute to the understanding the mechanism of PLE transposition, as well as design of new transposon systems with higher activity. Copyright © 2014 The Society for Biotechnology, Japan. Published by Elsevier B.V. All rights reserved.

  15. Chen Jingrun, China's famous mathematician: devastated by brain injuries on the doorstep to solving a fundamental mathematical puzzle.

    Science.gov (United States)

    Lei, Ting; Belykh, Evgenii; Dru, Alexander B; Yagmurlu, Kaan; Elhadi, Ali M; Nakaji, Peter; Preul, Mark C

    2016-07-01

    Chen Jingrun (1933-1996), perhaps the most prodigious mathematician of his time, focused on the field of analytical number theory. His work on Waring's problem, Legendre's conjecture, and Goldbach's conjecture led to progress in analytical number theory in the form of "Chen's Theorem," which he published in 1966 and 1973. His early life was ravaged by the Second Sino-Japanese War and the Chinese Cultural Revolution. On the verge of solving Goldbach's conjecture in 1984, Chen was struck by a bicyclist while also bicycling and suffered severe brain trauma. During his hospitalization, he was also found to have Parkinson's disease. Chen suffered another serious brain concussion after a fall only a few months after recovering from the bicycle crash. With significant deficits, he remained hospitalized for several years without making progress while receiving modern Western medical therapies. In 1988 traditional Chinese medicine experts were called in to assist with his treatment. After a year of acupuncture and oxygen therapy, Chen could control his basic bowel and bladder functions, he could walk slowly, and his swallowing and speech improved. When Chen was unable to produce complex work or finish his final work on Goldbach's conjecture, his mathematical pursuits were taken up vigorously by his dedicated students. He was able to publish Youth Math, a mathematics book that became an inspiration in Chinese education. Although he died in 1996 at the age of 63 after surviving brutal political repression, being deprived of neurological function at the very peak of his genius, and having to be supported by his wife, Chen ironically became a symbol of dedication, perseverance, and motivation to his students and associates, to Chinese youth, to a nation, and to mathematicians and scientists worldwide.

  16. Chinese Herbal Formulas Si-Wu-Tang and Er-Miao-San Synergistically Ameliorated Hyperuricemia and Renal Impairment in Rats Induced by Adenine and Potassium Oxonate

    Directory of Open Access Journals (Sweden)

    Yongping Guo

    2015-10-01

    Full Text Available Background/Aims: Hyperuricemia is an independent risk factor for chronic kidney disease and cardiovascular disease. Here, we examined the combined protective effects of Chinese herbal formula Si-Wu-Tang and Er-Miao-San on hyperuricemia and renal impairment in rats. Methods: Rats were randomly divided into normal rats, hyperuricemic rats, and hyperuricemic rats orally administrated with benzbromarone (4.5 mg·kg-1·d-1, Si-Wu-Tang (3.78 g·kg-1·d-1 and Si-Wu-Tang plus Er-Miao-San (6.48 g·kg-1·d-1 for 4 weeks. Hyperuricemic rats were orally gavaged with adenine (0.1 g·kg-1·d-1 and potassium oxonate (1.5 g·kg-1·d-1 daily for 4 weeks. Serum uric acid, creatinine, total cholesterol (TCH, triglyceride and blood urea nitrogen (BUN concentrations, as well as urinary uric acid and microalbuminuria were measured weekly. Serum xanthine oxidase (XOD activity and renal histopathology were also evaluated. The renal expression of organic anion transporter 1 (OAT1 and organic anion transporter 3 (OAT3 was detected by western blot. Results: Si-Wu-Tang plus Er-Miao-San lowered serum uric acid, creatinine, triglyceride and BUN levels to a greater degree than did Si-Wu-Tang alone. Si-Wu-Tang plus Er-Miao-San ameliorated microalbuminuria and renal histopathology, as well as decreased serum TCH concentration and XOD activity in hyperuricemic rats. Combination of Si-Wu-Tang and Er-Miao-San also led to a greater increase in OAT1 and OAT3 expression than did Siwutang alone. Conclusion: Si-Wu-Tang and Er-Miao-San synergistically ameliorated hyperuricemia and renal impairment in rats through upregulation of OAT1 and OAT3.

  17. Antifungal Activity of Isoliquiritin and Its Inhibitory Effect against Peronophythora litchi Chen through a Membrane Damage Mechanism

    Directory of Open Access Journals (Sweden)

    Jianjun Luo

    2016-02-01

    Full Text Available This study investigated the antifungal activity and potential antifungal mechanism(s of isoliquiritin against P. litchi Chen, one of the main litchi pathogens. The antifungal activity of isoliquiritin against P. litchi Chen had been proven in a dose-dependent manner through in vitro (mycelial growth and sporangia germination and in vivo (detached leaf tests. Results revealed that isoliquiritin exhibited significant antifungal activity against the tested pathogens, especially, P. litchi Chen, with a minimum inhibitory concentration of 27.33 mg/L. The morphology of P. litchi Chen was apparently changed by isoliquiritin through cytoplasm leakage and distortion of mycelia. The cell membrane permeability of the P. litchi Chen increased with the increasing concentration of isoliquiritin, as evidenced by a rise in relative electric conductivity and a decrease in reducing sugar contents. These results indicated that the antifungal effects of isoliquiritin could be explained by a membrane lesion mechanism causing damage to the cell membrane integrity leading to the death of mycelial cells. Taken together, isoliquiritin may be used as a natural alternative to commercial fungicides or a lead compound to develop new fungicides for the control of litchi downy blight.

  18. Newly described human polyomaviruses Merkel Cell, KI and WU are present in urban sewage and may represent potential environmental contaminants

    Directory of Open Access Journals (Sweden)

    Carratala Anna

    2010-06-01

    Full Text Available Abstract Recently, three new polyomaviruses (KI, WU and Merkel cell polyomavirus have been reported to infect humans. It has also been suggested that lymphotropic polyomavirus, a virus of simian origin, infects humans. KI and WU polyomaviruses have been detected mainly in specimens from the respiratory tract while Merkel cell polyomavirus has been described in a very high percentage of Merkel cell carcinomas. The distribution, excretion level and transmission routes of these viruses remain unknown. Here we analyzed the presence and characteristics of newly described human polyomaviruses in urban sewage and river water in order to assess the excretion level and the potential role of water as a route of transmission of these viruses. Nested-PCR assays were designed for the sensitive detection of the viruses studied and the amplicons obtained were confirmed by sequencing analysis. The viruses were concentrated following a methodology previously developed for the detection of JC and BK human polyomaviruses in environmental samples. JC polyomavirus and human adenoviruses were used as markers of human contamination in the samples. Merkel cell polyomavirus was detected in 7/8 urban sewage samples collected and in 2/7 river water samples. Also one urine sample from a pregnant woman, out of 4 samples analyzed, was positive for this virus. KI and WU polyomaviruses were identified in 1/8 and 2/8 sewage samples respectively. The viral strains detected were highly homologous with other strains reported from several other geographical areas. Lymphotropic polyomavirus was not detected in any of the 13 sewage neither in 9 biosolid/sludge samples analyzed. This is the first description of a virus isolated from sewage and river water with a strong association with cancer. Our data indicate that the Merkel cell polyomavirus is prevalent in the population and that it may be disseminated through the fecal/urine contamination of water. The procedure developed may

  19. His Excellency Mr Ken WU Ambassador Extraordinary and Plenipotentiary of the People’s Republic of China to Switzerland

    CERN Multimedia

    Jean Claude Gadmer

    2011-01-01

    Photo 1-5:The delegation visiting the ATLAS visitor Center with P.Jenni, ATLAS Collaboration former Spokesperson Photo 6-14,15-20:visiting the ATLAS experimental area Photo 15:Y. YANG,Attaché-Q. WAN,First Secretary-Z. Ren,ATLAS Collaboration,High Energy Group,Shandong University-H.E. Mr K. Wu-P. Jenni-R. Voss,Adviser for the People’s Republic of China-H. FENG,Counsellor Photo 21-38:Signature of the Guest Book with CERN Director-General R. Heuer

  20. Minimal contact CR submanifolds in S satisfying the δ(2)-Chen equality

    Science.gov (United States)

    Munteanu, Marian Ioan; Vrancken, Luc

    2014-01-01

    In his book on Pseudo-Riemannian geometry, δ-invariants and applications, B.Y. Chen introduced a sequence of curvature invariants. Each of these invariants is used to obtain a lower bound for the length of the mean curvature vector for an immersion in a real space form. A submanifold is called an ideal submanifold, for that curvature invariant, if and only if it realizes equality at every point. The first such introduced invariant is called δ(2). On the other hand, a well known notion for submanifolds of Sasakian space forms, is the notion of a contact CR-submanifold. In this paper we combine both notions and start the study of minimal contact CR-submanifolds which are δ(2) ideal. We relate this to a special class of surfaces and obtain a complete classification in arbitrary dimensions.

  1. Towards Transformation of Knowledge and Subjectivity in Curriculum Inquiry: Insights from Chen Kuan-Hsing's "Asia as Method"

    Science.gov (United States)

    Lin, Angel M. Y.

    2012-01-01

    Chen's book, "Asia as Method" (Duke University Press, 2010), and his theorization on topics of de-imperialization, de-colonization, de-cold war, as well as on foregrounding epistemologies and frames of reference situated in the diverse contexts in Asia have contributed to empowering scholars and researchers situated not only in Taiwan,…

  2. Control of the Fractional-Order Chen Chaotic System via Fractional-Order Scalar Controller and Its Circuit Implementation

    OpenAIRE

    Qiong Huang; Chunyang Dong; Qianbin Chen

    2014-01-01

    A fractional-order scalar controller which involves only one state variable is proposed. By this fractional-order scalar controller, the unstable equilibrium points in the fractional-order Chen chaotic system can be asymptotically stable. The present control strategy is theoretically rigorous. Some circuits are designed to realize these control schemes. The outputs of circuit agree with the results of theoretical results.

  3. On the automatic link between affect and tendencies to approach and avoid: Chen and Bargh (1999 revisited.

    Directory of Open Access Journals (Sweden)

    Mark eRotteveel

    2015-04-01

    Full Text Available Within the literature on emotion and behavioral action, studies on approach-avoidance take up a prominent place. Several experimental paradigms feature successful conceptual replications but many original studies have not yet been replicated directly. We present such a direct replication attempt of two seminal experiments originally conducted by Chen and Bargh (1999. In their first experiment, participants affectively evaluated attitude objects by pulling or pushing a lever. Participants who had to pull the lever with positively valenced attitude objects and push the lever with negatively valenced attitude objects (i.e., congruent instruction did so faster than participants who had to follow the reverse (i.e., incongruent instruction. In Chen and Bargh's second experiment, the explicit evaluative instructions were absent and participants merely responded to the attitude objects by either always pushing or always pulling the lever. Similar results were obtained as in Experiment 1. Based on these findings, Chen and Bargh concluded that (1 attitude objects are evaluated automatically; and (2 attitude objects automatically trigger a behavioral tendency to approach or avoid. We attempted to replicate both experiments and failed to find the effects reported by Chen and Bargh as indicated by our pre-registered Bayesian data analyses; nevertheless, the evidence in favor of the null hypotheses was only anecdotal, and definitive conclusions await further study.

  4. The impact of systematic landscape conservation planning on ecosystem: Chen Youlan river watershed

    Science.gov (United States)

    Chen, Chi-ju

    2017-04-01

    Heraclitus said that "no man ever steps in the same river twice." Everything continues to change. Land use change will keep redefine itself and subject the Earth and humankind to collateral changes. Humankind benefits from ecosystem in many ways. The ecosystem provides people with nutrients, enriches soil with sediment, and sustains all living organisms with water; these benefits are known as ecosystem services. In Taiwan, land use change has impacted ecosystem and biodiversity on various levels. Thus, we took six land use scenarios from 1999 to 2005 in Chen Youlan river watershed as our case study, intending to observe the course of ecosystem and biodiversity changes and the cause of it. Systematic Landscape conservation planning (SLCP) framework can be adopted when designing land use policy to safeguard human interests and ecosystem. This study use SLCP to develop ecosystem services and biodiversity protection strategies. Several strategies were designed by using 1999 to 2005 data as provision to protect the intactness of future ecosystem services and biodiversity. This research explores the potential and possible impacts of different land use protection strategies in the future. It is possible to identify the conservation priority of a certain region by using the Zonation meta-algorithm. This study selects the zonation critical protection area (Joint set of Yushan National Park) as strategy A, B and C. Strategy D takes Yushan National Park as a protected area; unstable hot spots in 1999/03 (Joint set of Yushan National Park) are selected as strategy E. Next, we used Kappa statistical method to find the minimal ecosystem services change and biodiversity hotspots change of the five aforementioned strategies and compared with those from 1999/03. By the Kappa statistical method, we further prioritized the important conservation areas by strategy A, B, C, E in the future. The results can not only serve as management reference for government agencies, but also develop

  5. Wormholes supported by phantom energy from Shan-Chen cosmological fluids

    Energy Technology Data Exchange (ETDEWEB)

    Wang, Deng [Nankai University, Theoretical Physics Division, Chern Institute of Mathematics, Tianjin (China); Meng, Xin-He [Nankai University, Department of Physics, Tianjin (China); Institute of Theoretical Physics, CAS, State key Lab of Theoretical Physics, Beijing (China)

    2016-03-15

    In the present paper, the exact solutions of spherically symmetrical Einstein field equations describing wormholes supported by phantom energy that violates the null energy condition from Shan-Chen background fluid are obtained. We have considered the important case of the model parameter ψ ∼ 1, which corresponds to the ''saturation effect'', and this regime corresponds to an effective form of ''asymptotic freedom'' for the fluids, but occurring at cosmological rather than subnuclear scales. Then we investigate the allowed range for the values of the model parameters g and ω when the spacetime metrics describe wormholes and discuss the possible singularities of the solutions, finding that the obtained spacetimes are geodesically complete. Furthermore, we construct two traversable wormholes through matching our obtained interior solutions to the exterior Schwarzschild solutions and analyze the traversabilities of the wormholes. Finally, we consider the case of anisotropic pressure and discover that the transverse pressure also crosses the phantom divide -1 with the growth of the wormhole dimension, and it tends to be the same as the radial pressure with the growth of the wormhole radius. (orig.)

  6. Psychometric properties of the Revised Chen Internet Addiction Scale (CIAS-R) in Chinese adolescents.

    Science.gov (United States)

    Mak, Kwok-Kei; Lai, Ching-Man; Ko, Chih-Hung; Chou, Chien; Kim, Dong-Il; Watanabe, Hiroko; Ho, Roger C M

    2014-10-01

    The Revised Chen Internet Addiction Scale (CIAS-R) was developed to assess Internet addiction in Chinese populations, but its psychometric properties in adolescents have not been examined. This study aimed to evaluate the factor structure and psychometric properties of CIAS-R in Hong Kong Chinese adolescents. 860 Grade 7 to 13 students (38 % boys) completed the CIAS-R, the Young's Internet Addiction Test (IAT), and the Health of the Nation Outcome Scales for Children and Adolescents (HoNOSCA) in a survey. The prevalence of Internet addiction as assessed by CIAS-R was 18 %. High internal consistency and inter-item correlations were reported for the CIAS-R. Results from the confirmatory factor analysis suggested a four-factor structure of Compulsive Use and Withdrawal, Tolerance, Interpersonal and Health-related Problems, and Time Management Problems. Moreover, results of hierarchical multiple regression supported the incremental validity of the CIAS-R to predict mental health outcomes beyond the effects of demographic differences and self-reported time spent online. The CIAS is a reliable and valid measure of internet addiction problems in Hong Kong adolescents. Future study is warranted to validate the cutoffs of the CIAS-R for identification of adolescents with Internet use problems who may have mental health needs.

  7. Two Novel Hepatocellular Carcinoma Cycle Inhibitory Cyclodepsipeptides from a Hydrothermal Vent Crab-Associated Fungus Aspergillus clavatus C2WU

    Directory of Open Access Journals (Sweden)

    Wei Jiang

    2013-12-01

    Full Text Available Two novel cyclodepsipeptides containing an unusual anthranilic acid dimer and a d-phenyllactic acid residues, clavatustides A (1 and B (2, were identified from cultured mycelia and broth of Aspergillus clavatus C2WU isolated from Xenograpsus testudinatus, which lives at extreme, toxic habitat around the sulphur-rich hydrothermal vents in Taiwan Kueishantao. This is the first example of cyclopeptides containing an anthranilic acid dimer in natural products, and the first report of microbial secondary metabolites from the hydrothermal vent crab. Clavatustides A (1 and B (2 suppressed the proliferation of hepatocellular carcinoma (HCC cell lines (HepG2, SMMC-7721 and Bel-7402 in a dose-dependent manner, and induced an accumulation of HepG2 cells in G1 phase and reduction of cells in S phase.

  8. Etika v čínské debatě o vědě a životních názorech: Wu Zhihui

    OpenAIRE

    Typl, Lukáš

    2017-01-01

    The aim of this thesis is to eleborate a detailed analysis of Wu Zhihui`s essay: New faith and its view of the universe and of man and attempts to fill the still large gap in secondary literature. The method focuses on basic interpretations of Wu Zhihui's ideas and putting them into the context of Western philosophy. It emphasizes direct quotations and translations of key texts to Czech language. Through the analysis of his view of faith, knowledge, metaphysics, cosmology, ontology and human ...

  9. Politics in the Western Maya Region (I: Ajawil/Ajawlel and Ch'e'n

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    Péter Bíró

    2011-01-01

    Full Text Available In a series of articles I reflect on the use of various expressions which are connected to what we call the political in the inscriptions of the Classic Maya Western Region. These words express concepts which help to understand the intricate details of the interactions between the political entities and their internal organisations in the Classic Maya Lowlands. Words such as 7ajawil, 7ajawlel, the kennings built on the base of ch'e7n (cave, pond, the emblem glyphs and titles will be examined in light of what they tell us about the functioning of the political organisation of the Classic Period in a constrained region.En una serie de artículos como éste investigo el uso de varias palabras en las inscripciones mayas de la época Clásica de la Región Occidental vinculadas con lo que nosotros llamamos "política". Estas palabras expresan conceptos que ayudan a entender los matices de las relaciones entre las entidades políticas de las Tierras Bajas Mayas y su organización interna. Términos como ajaw'ü I ajawlel, los difrasismos con base ch'e'n (cueva, pozo, los glifos emblemas y los títulos serán examinados tomando en cuenta la información que nos proporcionan sobre el funcionamiento de la organización política de la época Clásica en una región restringida.

  10. Writing Beyond the Wall: Translation, Cross-cultural Exchange, and Chen Ran's 'A Private Life'

    Directory of Open Access Journals (Sweden)

    Kay Schaffer

    2006-09-01

    Full Text Available The past decade has witnessed an unprecedented rise in the global flow of knowledge, nowhere more apparent in the exchange of ideas between China and modern western democracies. Our interest concerns one aspect of this global flow— the translation of Chinese women’s autobiographical writing into English. Taking Chen Ran’s A Private Life (English edition, 2004 as a point of departure, the paper explores issues of translingual practice and cross-cultural exchange. It considers what escapes or is lost in translation as well as the additive potential of the host text. It is sometimes the case that the translation can deliberately make certain ambiguities visible—whether from pragmatic, market-driven motivations or from more complex political, historical and cultural considerations. These negotiations of meaning that occur in the translation process can reverberate on the critical reception of texts in both the ‘guest’ and ‘host’ languages (Liu 1995, with open-ended, incomplete and indeterminate effects. The paper examines the effects of the omission of a brief parenthetical section of three paragraphs from one chapter of the Chinese edition of A Private Life. Yet, even that small emendation changes the original text as a cultural object and alters potential modes of its reception. In this case, the translation results in a loss of ambiguity, irony, philosophic and rhetorical sophistication while also offering additive potentials that enhance the generation of new meanings in the translingual exchange, here with reference Tiananmen and contemporary feminism in China. The translation process provides new channels for readers, writers and theorists to dialogue and communicate across gaps of difference, despite inhibiting factors like the imposition of local restraints, the universalising pressures of western modernity, and asymmetrical relations of power between guest and host language contexts.

  11. Aktivitätsmessung auf nukleinsäuremodifizierten Oberflächen

    Science.gov (United States)

    Schmidt, Peter Michael

    2003-06-01

    Im Bereich der medizinischen Diagnostik spielen DNA-Chips eine immer wichtigere Rolle. Dabei werden Glas- oder Silikon-Oberflächen mit Tausenden von einzelsträngigen DNA-Fragmenten, sog. Sonden, bestückt, die mit den passenden DNA-Fragmenten in der zugefügten Patientenprobe verschmelzen. Die Auswertung solcher Messungen liefert die Diagnose für Krankheiten wie z.B. Krebs, Alzheimer oder für den Nachweis pathogener Erreger. Durch fortschreitende Miniaturisierung dieser Meßsysteme können bis zu 40.000 Genfragmente des Menschen in einer einzigen Messung analysiert werden. Neben den DNA-Fragmenten können Bio-Chips auch für andere biologische Komponenten wie Antikörper und Proteine eingesetzt werden, wobei bei letzteren neben der Bindung auch die Aktivität ein wichtiger Diagnoseparamter ist. Am Fraunhofer-Institut für medizinische Technik und am Lehrstuhl für Analytische Biochemie der Universität Potsdam wurden im Rahmen einer Doktorarbeit Methoden entwickelt, die es ermöglichen auf nukleinsäuremodifizierten Sensoroberflächen die Aktivität von Proteinen zu messen. Es wurden Nukleinsäuren auf Oberflächen optischer Sensoren verankert. Diese fungierten als Rezeptor für die Proteine sowie auch als Substrat für Restriktionsenzyme, die Nukleinsäuren schneiden und Polymerasen, die Nukleinsäuren synthetisieren und verlängern können. Seine Anwendung fand diese Messmethode in der Messung der Aktivität des Proteins Telomerase, das in 90% aller Tumore erhöhte Aktivität gegenüber gesunden Zellen aufweist. Die Vorteile dieses neuen Assays gegenüber älteren Methoden liegt im Verzicht auf radioaktiv-markierten Komponenten und einer deutlich verkürzten Analysezeit. Die Arbeit schliesst mit einem funktionsfähigen Nachweis der Telomeraseaktivität im Zellextrakt von gesunden und kranken Zellen. Der direkte Einfluß von Hemmstoffen auf die Aktivität konnte sichtbar gemacht werden, und steht daher bei der Entwicklung neuer Tumor-Diagnostika und

  12. Control of the Fractional-Order Chen Chaotic System via Fractional-Order Scalar Controller and Its Circuit Implementation

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    Qiong Huang

    2014-01-01

    Full Text Available A fractional-order scalar controller which involves only one state variable is proposed. By this fractional-order scalar controller, the unstable equilibrium points in the fractional-order Chen chaotic system can be asymptotically stable. The present control strategy is theoretically rigorous. Some circuits are designed to realize these control schemes. The outputs of circuit agree with the results of theoretical results.

  13. [Academic thoughts on Practice of acupuncture and moxibustion written by CHEN Jingwen, the acupuncture master in the Republic of China].

    Science.gov (United States)

    Huang, Weiping; Li, Naiqi

    2015-03-01

    Through the collection of Practice of acupuncture and moxibustion written by CHEN Jingwen, the acupuncture master in the Republic of China, the academic characteristics on acupuncture and moxibusiton were analyzed. The literature comparison method was adopted to compare the works of LUO Zhaoju, ZENG Tianzhi and LI Wenxian, etc. at the same period. It was discovered that CHEN Jingwen was the medical master who systematicly brought up the theory of acupoint properties earlier in the modern times. Classifying drugs based on acupoints was his academic feature. Additionally, the compatibility therapy of Chinese medicine was introduced to explain the essential ideas on the acupoints combination. The treatment was determined on the basis of zangxiang theory and the reinforcing and reducing therapy of acupuncture was emphasized in the determination of treatment and prescription. CHEN Jingwen's theory of acupoint property had been stressed and spread among the medical scholars in the Republic of China and he had made the beneficial exploration for the development of modern acupuncture and moxibustion therapy.

  14. Cryptanalysis and improvement of Chen-Hsiang- Shih’s remote user authentication scheme using smart cards

    Directory of Open Access Journals (Sweden)

    Rafael Martínez-Peláez

    2013-01-01

    Full Text Available Recientemente, Chen-Hsiang-Shih propusieron un nuevo esquema de autenticación de usuario remoto basado en un identificador dinámico. Los autores afirman que su esquema es más seguro que los trabajos previos. Sin embargo, se demuestra que su esquema continúa siendo inseguro contra diferentes tipos de ataques. Con el fin de mejorar la seguridad del esquema propuesto por Chen-Hsiang-Shih, se propone un esquema que consigue los siguientes objetivos de seguridad: el esquema no requiere de una tabla de verificación, cada usuario elige y cambia su contraseña libremente, cada usuario mantiene su contraseña en secreto, el esquema requiere autenticación mutua, el esquema establece una clave de sesión después de una autenticación correcta, y el esquema mantiene el anonimato del usuario. El análisis de seguridad y la comparación demuestran que nuestro esquema es más seguro que el esquema propuesto por Das-Saxena-Gulati, Wang-Liu-Xiao-Dan, y Chen-Hsiang-Shih.

  15. No Evidence of Human Polyomavirus 9, WU and KI DNA in Kidney and Urinary Bladder Tumour Tissue Samples.

    Science.gov (United States)

    Csoma, Eszter; Bidiga, László; Méhes, Gábor; Gergely, Lajos

    2016-01-01

    The oncogenic potential of human polyomaviruses (HPyVs) has been proposed, but so far only Merkel cell carcinoma polyomavirus seems to be associated with a human tumour. The role of BK polyomavirus (BKPyV) in human tumourigenesis remains controversial. BKPyV establishes persistent infection in the urinary tract, and renal and bladder neoplasms have been studied extensively, but conflicting prevalence data are reported. KI, WU and HPyV9 were detected in urine samples suggesting that these viruses may also infect the urinary tract, but their presence in urinary tract tumours has not been studied. The aim of this work was to examine the prevalence of KIPyV, WUPyV, HPyV9 and BKPyV by PCR in renal and bladder neoplasms. A total of 190 formalin-fixed paraffin-embedded renal neoplasms, bladder cancer and kidney biopsy samples were analysed for the presence of BKPyV, KIPyV, WUPyV and HPyV9 DNA by real-time and nested PCR. Amplifiable DNA was extracted from all the samples, but none of the studied viruses were detected in benign renal neoplasia (0/23), malignant renal tumours (0/89) or bladder cancer (0/76). Our study did not find any evidence that BKPyV, KIPyV, WUPyV or HPyV9 are associated with bladder and renal tumours. © 2016 S. Karger AG, Basel.

  16. Biofunktionalisierung von Implantatoberflächen mit einem synthetisch hergestellten Peptid (P15) bei diabetischen Versuchstieren gegenüber gesunden Versuchstieren

    OpenAIRE

    abu-Nasir, Mohammed

    2014-01-01

    1. Zusammenfassung 1.1 Hintergrund und Ziele Die zunehmende Prävalenz von Diabetes mellitus in Deutschland rückt dieses Patientenklientel näher in den Fokus der Implantologie . In dieser Studie wurde der Einfluss von sandgestrahlten und geätzten Implantatoberflächen mit einer Peptidsequenz (P15) beschichteten Oberflächen auf die Implantateinheilung bei diabetischen Versuchstieren gegenüber gesunden Versuchstieren untersucht. 1.2 Material und Methoden Insgesamt wurden...

  17. The spatial and temporal expression of Ch-en, the engrailed gene in the polychaete Chaetopterus, does not support a role in body axis segmentation

    Science.gov (United States)

    Seaver, E. C.; Paulson, D. A.; Irvine, S. Q.; Martindale, M. Q.

    2001-01-01

    We are interested in understanding whether the annelids and arthropods shared a common segmented ancestor and have approached this question by characterizing the expression pattern of the segment polarity gene engrailed (en) in a basal annelid, the polychaete Chaetopterus. We have isolated an en gene, Ch-en, from a Chaetopterus cDNA library. Genomic Southern blotting suggests that this is the only en class gene in this animal. The predicted protein sequence of the 1.2-kb cDNA clone contains all five domains characteristic of en proteins in other taxa, including the en class homeobox. Whole-mount in situ hybridization reveals that Ch-en is expressed throughout larval life in a complex spatial and temporal pattern. The Ch-en transcript is initially detected in a small number of neurons associated with the apical organ and in the posterior portion of the prototrochophore. At later stages, Ch-en is expressed in distinct patterns in the three segmented body regions (A, B, and C) of Chaetopterus. In all segments, Ch-en is expressed in a small set of segmentally iterated cells in the CNS. In the A region, Ch-en is also expressed in a small group of mesodermal cells at the base of the chaetal sacs. In the B region, Ch-en is initially expressed broadly in the mesoderm that then resolves into one band/segment coincident with morphological segmentation. The mesodermal expression in the B region is located in the anterior region of each segment, as defined by the position of ganglia in the ventral nerve cord, and is involved in the morphogenesis of segment-specific feeding structures late in larval life. We observe banded mesodermal and ectodermal staining in an anterior-posterior sequence in the C region. We do not observe a segment polarity pattern of expression of Ch-en in the ectoderm, as is observed in arthropods. Copyright 2001 Academic Press.

  18. Traditional uses, botany, phytochemistry, pharmacology and toxicology of Panax notoginseng (Burk.) F.H. Chen: A review.

    Science.gov (United States)

    Wang, Ting; Guo, Rixin; Zhou, Guohong; Zhou, Xidan; Kou, Zhenzhen; Sui, Feng; Li, Chun; Tang, Liying; Wang, Zhuju

    2016-07-21

    Panax notoginseng (Burk.) F.H. Chen is a widely used traditional Chinese medicine known as Sanqi or Tianqi in China. This plant, which is distributed primarily in the southwest of China, has wide-ranging pharmacological effects and can be used to treat cardiovascular diseases, pain, inflammation and trauma as well as internal and external bleeding due to injury. This paper provides up-to-date information on investigations of this plant, including its botany, ethnopharmacology, phytochemistry, pharmacology and toxicology. The possible uses and perspectives for future investigation of this plant are also discussed. The relevant information on Panax notoginseng (Burk.) F.H. Chen was collected from numerous resources, including classic books about Chinese herbal medicine, and scientific databases, including Pubmed, SciFinder, ACS, Ebsco, Elsevier, Taylor, Wiley and CNKI. More than 200 chemical compounds have been isolated from Panax notoginseng (Burk.) F.H. Chen, including saponins, flavonoids and cyclopeptides. The plant has pharmacological effects on the cardiovascular system, immune system as well as anti-inflammatory, anti-atherosclerotic, haemostatic and anti-tumour activities, etc. Panax notoginseng is a valuable traditional Chinese medical herb with multiple pharmacological effects. This review summarizes the botany, ethnopharmacology, phytochemistry, pharmacology and toxicology of P. notoginseng, and presents the constituents and their corresponding chemical structures found in P. notoginseng comprehensively for the first time. Future research into its phytochemistry of bio-active components should be performed by using bioactivity-guided isolation strategies. Further work on elucidation of the structure-function relationship among saponins, understanding of multi-target network pharmacology of P. notoginseng, as well as developing its new clinical usage and comprehensive utilize will enhance the therapeutic potentials of P. notoginseng. Copyright © 2016

  19. Pauropods (Myriapoda: Pauropoda) from Eastern China, descriptions of three new species and revision of Pauropus bifurcus Zhang & Chen, 1988.

    Science.gov (United States)

    Qian, Changyuan; Dong, Yan; Guo, Hua; Chu, Kelin; Sun, Hongying

    2013-01-17

    Pauropods from Zhejiang and Jiangsu in eastern China were collected from the field. Among 23 specimens, four species assigned to two genera are identified. Three of these species are new and from the genus Decapauropus Remy, 1931: Decapauropus bifurcodicoccus Qian & Dong sp. nov., D. duomamillatus Qian & Dong sp. nov. and D. bidrepanoides Qian sp. nov. The status of Pauropus bifurcus Zhang & Chen, 1988 is reexamined and reallocated to the genus Stylopauropus Cook, 1896. A key to Decapauropus species of eastern China (including Jiangsu, Anhui and Zhejiang province) is provided.

  20. Equity Valuation and Accounting Numbers: Applying Zhang (2000 and Zhang and Chen (2007 models to Brazilian Market

    Directory of Open Access Journals (Sweden)

    Fernando Caio Galdi

    2011-03-01

    Full Text Available This paper investigates how accounting variables explain cross-sectional stocks returns in Brazilian capital markets. The analysis is based on Zhang (2000 and Zhang and Chen (2007 models. These models predict that stock returns are a function of net income, change in profitability, invested capital, changes in opportunity growths and discount rate. Generally, the empirical results for the Brazilian capital market are consistent with the theoretical relations that models describe, similarly to the results found in the US. Using different empirical tests (pooled regressions, Fama-Macbeth and panel data the results and coefficients remain similar, what support the robustness of our findings.

  1. [A Study on the quotations in the Wu xing da yi (The Gist of Five Phases) cited from Nei jing (Inner Canon)].

    Science.gov (United States)

    Wang, Zheng-Shan; Zhang, Qi-Cheng

    2013-07-01

    In the Wu xing da yi (The Gist of Five Phases), written by Xiao Ji of the Sui Dynasty, there were 9 quotations cited from Huang di nei jing (Inner Canon of Huangdi). By comparison with current version of Huang di nei jing, most of the descriptions are similar, yet still with some differences, such as yin-yang nature of the five zang visceras, the liver being the root of "pi ji", the spleen being the root of "cang lin" etc. Wu xing da yi epitomizes the books about yin-yang and five phases before the Sui Dynasty, while Xiao Ji's quotations from Huang di nei jing interpreted from the views of yin-yang and five phases, are different from the annotations of later ages.

  2. Chemical profiling of Di-Wu-Yang-Gan Granules by ultra performance liquid chromatography coupled to quadrupole time-of-flight mass spectrometry with MSE technology.

    Science.gov (United States)

    Tian, Dong; Zhou, Chao; Jia, Hong-Mei; Yu, Meng; Chang, Xing; Zhang, Hong-Wu; Ba, Yuan-Ming; Zou, Zhong-Mei

    2017-08-08

    Di-Wu-Yang-Gan Granules is a Traditional Chinese Medicine prescription used for the treatment of HBeAg-negative chronic hepatitis B patients in China. It consists of five commonly used Chinese herbs. However, the chemical constituents of the whole prescription had not been clarified yet. Hence, in this study, the chemical profiling of Di-Wu-Yang-Gan Granules was explored by ultra performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometry, which can provide accurate molecular weight within 5-ppm error and sufficient MS/MS fragment ions without the need for precursor ion selection. As a result, 116 compounds were identified, including lignans, triterpenesaponins, flavonoids, coumarins, iridoids, nortriterpenoids, phenolic acids, and sesquiterpenes. All compounds were further assigned to the individual herbs. In conclusion, this established method was reliable and effective for the separation and identification of the constituents in Di-Wu-Yang-Gan Granules. The findings are beneficial for quality control of the prescription during production and provide helpful chemical information for exploring its efficacy and the mechanism of action. The fragmentation regularity summarized in this study also provided important information for the rapid identification of the chemical composition in herbal medicines or their prescription.

  3. Influence of filling-drawdown cycles of the Three Gorges reservoir on deformation and failure behaviors of anaclinal rock slopes in the Wu Gorge

    Science.gov (United States)

    Huang, Da; Gu, Dong Ming

    2017-10-01

    The upper Wu Gorge on the Yangtze River has been the site of tens of reservoir-induced landslides since the filling of the Three Gorges reservoir in 2003. These landslides have been occurring in heavily fractured carbonate rock materials along the rim of the reservoir in the Wu Gorge. A detailed investigation was carried out to examine the influence of reservoir operations (filling and drawdown) on slope stabilities in the upper Wu Gorge. Field investigations reveal many collapses of various types occurred at the toe of the anaclinal rock slopes, owing to the long-term intensive river erosion caused by periodic fluctuation of the reservoir level. Analysis of data from deformation monitoring suggests that the temporal movement of the slopes shows seasonal fluctuations that correlate with reservoir levels and drawdown conditions, with induced slope acceleration peaking when reservoir levels are lowest. This may illustrate that the main mechanism is the reservoir drawdown, which induces an episodic seepage force in the highly permeable materials at the slope toes, and thus leads to the episodic rockslides. The coupled hydraulic-mechanical (HM) modeling of the G2 landslide, which occurred in 2008, shows that collapse initiated at the submerged slope toe, which then caused the upper slope to collapse in a rock topple-rock slide pattern. The results imply that preventing water erosion at the slope toe might be an effective way for landslide prevention in the study area.

  4. Feasibility and effectiveness of a Chen-style Tai Chi programme for stress reduction in junior secondary school students.

    Science.gov (United States)

    Lee, Linda Y K; Chong, Yeuk Lan; Li, Ngai Yin; Li, Man Chung; Lin, Lai Na; Wong, Lee Yi; Wong, Brian Kit; Yip, Wing Ping; Hon, Cho Hang; Chung, Pui Kuen; Man, Shuk Yee

    2013-04-01

    Stress is common in junior secondary school students (JSSS). This study aimed to determine the feasibility and effectiveness of a Chen-style Tai Chi programme for stress reduction in JSSS. A non-equivalent pre-test/post-test control group design was adopted, and a convenience sample of 69 JSSS was recruited. The experimental group (n = 32) joined a Chen-style Tai Chi programme, which included 10 sessions of 80-minute Tai Chi training (one session per week). The control group (n = 37) proceeded with self-study. Participants' stress levels were assessed using the Perceived Stress Scale. Feasibility was determined as the percentage of participants completing and attending the programme. Effectiveness was measured as the significant difference in changes in stress levels before and after the intervention between the two groups. Results preliminarily supported that the programme was feasible for JSSS. Completion rate was 100%, and attendance rate was 90%. However, no significant difference was noted in changes in stress levels before and after the intervention between the two groups. The potential health benefits of Tai Chi could not be detected owing to the restrictions imposed by the research setting and study limitations. The present study represents initial efforts in this direction and serves as reference for future study. Copyright © 2012 John Wiley & Sons, Ltd.

  5. [A molecular epidemiological study of KI polyomavirus and WU polyomavirus in children with acute respiratory infection in Tianjin, China].

    Science.gov (United States)

    Lin, Shu-Xiang; Wang, Wei; Guo, Wei; Yang, Hong-Jiang; Ma, Bai-Cheng; Fang, Yu-Lian; Xu, Yong-Sheng

    2017-07-01

    To investigate the relationship of KI polyomavirus (KIPyV) and WU polyomavirus (WUPyV) with acute respiratory infection in children in Tianjin, China. A total of 3 730 nasopharyngeal secretions were collected from hospitalized children with acute respiratory infection in Tianjin Children's Hospital from January 2011 to December 2013. Viral nucleic acid was extracted, and virus infection (KIPyV and WUPyV) was determined by PCR. Some KIPyV-positive and WUPyV-positive PCR products were subjected to sequencing. Sequencing results were aligned with the known gene sequences of KIPyV and WUPyV to construct a phylogenetic tree. Amplified VP1 fragments of KIPyV were inserted into the cloning vector (PUCm-T) transformed into E. coli competent cells. Positive clones were identified by PCR and sequencing. The nucleotide sequences were submitted to GenBank. In addition, another seven common respiratory viruses in all samples were detected by direct immunofluorescence assay. In the 3 730 specimens, the KIPyV-positive rate was 12.14% (453/3 730) and the WUPyV-positive rate was 1.69% (63/3 730). The mean infection rate of KIPyV was significantly higher in June and July, while the mean infection rate of WUPyV peaked in February and March. Most of the KIPyV-positive or WUPyV-positive children were infections with KIPyV, WUPyV, and other respiratory viruses were observed in the children. The co-infection rate was 2.31% (86/3 730) and there were nine cases of co-infections with WUPyV and KIPyV. Thirty-five KIPyV-positive and twelve WUPyV-positive PCR products were sequenced and the alignment analysis showed that they had high homology with the known sequences (94%-100% vs 95%-100%). The VP1 gene sequences obtained from two KIPyV strains in this study were recorded in GenBank with the accession numbers of KY465925 and KY465926. For some children with acute respiratory infection in Tianjin, China, the acute respiratory infection may be associated with KIPyV and WUPy

  6. Three new anti-HBV active constituents from the traditional Chinese herb of Yin-Chen (Artemisia scoparia).

    Science.gov (United States)

    Geng, Chang-An; Huang, Xiao-Yan; Chen, Xing-Long; Ma, Yun-Bao; Rong, Guang-Qing; Zhao, Yong; Zhang, Xue-Mei; Chen, Ji-Jun

    2015-12-24

    Yin-Chen is a famous traditional Chinese medicine (TCM) in China for the treatment of acute and chronic hepatitis. Two species, namely Artemisia scoparia and Artemisia capillaris, are documented in Chinese Pharmacopoeia as the authentic resources for Yin-Chen. Previous investigation has proved that chlorogenic acid analogs and phenolic acids are two main types of the anti-HBV active constituents of A. capillaris. However, there is no investigation concerned with the anti-HBV components of A. scoparia. The aim of the present study is to recognize the new anti-HBV constituents of A. scoparia by detailed LCMS analyses. LCMS and bioassay-guided fractionation on the active part of A. scoparia led to the isolation of three new compounds. Their structures were determined by detailed spectroscopic analyses. Anti-HBV assay involving inhibition on HBsAg and HBeAg secretions and HBV DNA replication were performed in virto on HepG 2.2.15 cell line. The 90% ethanol extract of A. scoparia was revealed with anti-HBV activity for the first time, which was further separated into several fractions by column chromatography. Fr. D-4 was revealed with the highest anti-HBV activity, from which three new compounds including one unusual 4-pyridone glucoside (1) and two polyacetylene glucosides (2-3) were isolated under the guidance of LCMS analyses. Compounds 1-3 exhibited activity against the secretions of HBsAg and HBeAg, and HBV DNA replication. In particular, compounds 2 and 3 inhibited HBV DNA replication with IC50 values of 0.07 ± 0.04 and 0.012 ± 0.05 mM, with SI values of 23.6 and 17.1, respectively. Based on the MS/MS experiment, the fragmentation pathways of 1 in both positive and negative modes, and 2 and 3 in negative mode were proposed. The ion pairs of 388-208 (positive) and 432-206 (negative) for 1, 503-341 (negative) for 2, and 503-203 (negative) for 3, could be recognized as their respective diagnostic ions. The first time investigation on the anti-HBV constituents of A

  7. Development of the Fray-Farthing-Chen Cambridge Process: Towards the Sustainable Production of Titanium and Its Alloys

    Science.gov (United States)

    Hu, Di; Dolganov, Aleksei; Ma, Mingchan; Bhattacharya, Biyash; Bishop, Matthew T.; Chen, George Z.

    2018-02-01

    The Kroll process has been employed for titanium extraction since the 1950s. It is a labour and energy intensive multi-step semi-batch process. The post-extraction processes for making the raw titanium into alloys and products are also excessive, including multiple remelting steps. Invented in the late 1990s, the Fray-Farthing-Chen (FFC) Cambridge process extracts titanium from solid oxides at lower energy consumption via electrochemical reduction in molten salts. Its ability to produce alloys and powders, while retaining the cathode shape also promises energy and material efficient manufacturing. Focusing on titanium and its alloys, this article reviews the recent development of the FFC-Cambridge process in two aspects, (1) resource and process sustainability and (2) advanced post-extraction processing.

  8. Landscape change and its effects on the wintering range of a lesser snow goose Chen caerulescens caerulescens population: A review

    Science.gov (United States)

    Robertson, Donna G.; Slack, R. Douglas

    1995-01-01

    The Texas coast has experienced considerable urban, industrial, and agricultural growth during the 20th Century. The region provides important wintering habitat to many avian species, including lesser snow geese Chen caerulescens caerulescens. This paper draws the biological and ecological fields into an historical perspective by examining available literature on the development of the upper Texas coast and range changes of lesser snow geese. Historically, lesser snow geese wintered in the coastal marshes, but expanded their range into the adjacent prairies in the mid-1900s. Winter range expansion was negatively affected by urban and industrial encroachment in the coastal marshes and positively influenced by agricultural development in the prairies, which increased dramatically during World War II. The lesser snow goose population flourished alongside some human-induced landscape alterations. However, projected declines in agriculture and increased urbanization of prairie and coastal marsh habitats may result in significant negative effects on the lesser snow goose population.

  9. Overexpression of the NADP+-specific isocitrate dehydrogenase gene (icdA) in citric acid-producing Aspergillus niger WU-2223L.

    Science.gov (United States)

    Kobayashi, Keiichi; Hattori, Takasumi; Hayashi, Rie; Kirimura, Kohtaro

    2014-01-01

    In the tricarboxylic acid (TCA) cycle, NADP(+)-specific isocitrate dehydrogenase (NADP(+)-ICDH) catalyzes oxidative decarboxylation of isocitric acid to form α-ketoglutaric acid with NADP(+) as a cofactor. We constructed an NADP(+)-ICDH gene (icdA)-overexpressing strain (OPI-1) using Aspergillus niger WU-2223L as a host and examined the effects of increase in NADP(+)-ICDH activity on citric acid production. Under citric acid-producing conditions with glucose as the carbon source, the amounts of citric acid produced and glucose consumed by OPI-1 for the 12-d cultivation period decreased by 18.7 and 10.5%, respectively, compared with those by WU-2223L. These results indicate that the amount of citric acid produced by A. niger can be altered with the NADP(+)-ICDH activity. Therefore, NADP(+)-ICDH is an important regulator of citric acid production in the TCA cycle of A. niger. Thus, we propose that the icdA gene is a potentially valuable tool for modulating citric acid production by metabolic engineering.

  10. Age and gender distribution of Hepatitis C virus prevalence and genotypes of individuals of physical examination in WuHan, Central China.

    Science.gov (United States)

    Niu, ZhiLi; Zhang, PingAn; Tong, YongQing

    2016-01-01

    Approximately 170 million people in the world are infected with Hepatitis C virus (HCV). There are no published population based studies about the prevalence of HCV genotypes and the associations of genotype and Infection frequency with gender and age in WuHan. We aimed to investigate the distribution of HCV prevalence and genotypes among different gender and age patients with chronic HCV infection in WuHan from 2011 to 2015. A total of 2685 anti-HCV positive serum samples from individuals of physical examinationwere recruited from the Renmin Hospital of WuHan University, Hubei Province in China from January 2011 to December 2015. From these 2685 anti-HCV positive serum samples, 496 samples were with a positive PCR for HCV RNA. The number of HCV infection showed an increase with year, but the annual infection rate has remained similar (χ(2) = 2.94, P = 0.568). 2685 cases were infected with HCV from 2011 to 2015 in WuHan city of China. Blood transfusion (18.14 %) was the main routs of transmission, followed by Surgery (8.94 %). The highest prevalence of HCV infection was at the age group 50-59 (25.85 % of 2685) and the lowest prevalence was 0-9 (0.93 % of 2685). HCV genotype 1 was the most prevalent (73.39 %), followed by genotypes 2 (17.14 %), 3 (5.25 %) and 6 (3.22 %). Genotype 4 and 5 was not detected in these patients. The most prevalent subtype was subtype 1b (71.98 %), followed by genotypes 2a (17.14 %). Five patients had mixed infection across the HCV subtypes. Among all genotypes, genotype 1 was highest in both male (73.27 %) and female (73.47 %) patients, followed by genotype 2. Genotype 1 (male: 29.84 % of 496, vs female: 43.55 % of 496, χ(2) = 20.07, P < 0.0001), genotype 2 (male: 6.25 % of 496, vs female: 10.89 % of 496, χ(2) = 6.81, P = 0.009), and 6 (male: 1.41 % of 496, vs female: 1.81 % of 496, χ(2) = 0.626, P = 0.401) were more common in female patients than males, while no significant gender differences were

  11. Screening for Internet Addiction: An Empirical Study on Cut-off Points for the Chen Internet Addiction Scale

    Directory of Open Access Journals (Sweden)

    Chih-Hung Ko

    2005-12-01

    Full Text Available The aim of this study was to establish the optimal cut-off points of the Chen Internet Addiction Scale (CIAS, to screen for and diagnose Internet addiction among adolescents in the community by using the well- established diagnostic criteria of Internet addiction. This survey of 454 adolescents used screening (57/58 and diagnostic (63/64 cut-off points of the CIAS, a self-reported instrument, based on the results of systematic diagnostic interviews by psychiatrists. The area under the curve of the receiver operating characteristic curve revealed that CIAS has good diagnostic accuracy (89.6%. The screening cut-off point had high sensitivity (85.6% and the diagnostic cut-off point had the highest diagnostic accuracy, classifying 87.6% of participants correctly. Accordingly, the screening point of the CIAS could provide a screening function in two-stage diagnosis, and the diagnostic point could serve as a diagnostic criterion in one-stage massive epidemiologic research.

  12. Satellite-derived land covers for runoff estimation using SCS-CN method in Chen-You-Lan Watershed, Taiwan

    Science.gov (United States)

    Zhang, Wen-Yan; Lin, Chao-Yuan

    2017-04-01

    The Soil Conservation Service Curve Number (SCS-CN) method, which was originally developed by the USDA Natural Resources Conservation Service, is widely used to estimate direct runoff volume from rainfall. The runoff Curve Number (CN) parameter is based on the hydrologic soil group and land use factors. In Taiwan, the national land use maps were interpreted from aerial photos in 1995 and 2008. Rapid updating of post-disaster land use map is limited due to the high cost of production, so the classification of satellite images is the alternative method to obtain the land use map. In this study, Normalized Difference Vegetation Index (NDVI) in Chen-You-Lan Watershed was derived from dry and wet season of Landsat imageries during 2003 - 2008. Land covers were interpreted from mean value and standard deviation of NDVI and were categorized into 4 groups i.e. forest, grassland, agriculture and bare land. Then, the runoff volume of typhoon events during 2005 - 2009 were estimated using SCS-CN method and verified with the measured runoff data. The result showed that the model efficiency coefficient is 90.77%. Therefore, estimating runoff by using the land cover map classified from satellite images is practicable.

  13. A variational numerical method based on finite elements for the nonlinear solution characteristics of the periodically forced Chen system

    Science.gov (United States)

    Khan, Sabeel M.; Sunny, D. A.; Aqeel, M.

    2017-09-01

    Nonlinear dynamical systems and their solutions are very sensitive to initial conditions and therefore need to be approximated carefully. In this article, we present and analyze nonlinear solution characteristics of the periodically forced Chen system with the application of a variational method based on the concept of finite time-elements. Our approach is based on the discretization of physical time space into finite elements where each time-element is mapped to a natural time space. The solution of the system is then determined in natural time space using a set of suitable basis functions. The numerical algorithm is presented and implemented to compute and analyze nonlinear behavior at different time-step sizes. The obtained results show an excellent agreement with the classical RK-4 and RK-5 methods. The accuracy and convergence of the method is shown by comparing numerically computed results with the exact solution for a test problem. The presented method has shown a great potential in dealing with the solutions of nonlinear dynamical systems and thus can be utilized in delineating different features and characteristics of their solutions.

  14. Plasma biochemistry values in emperor geese (Chen canagica) in Alaska: comparisons among age, sex, incubation, and molt.

    Science.gov (United States)

    Franson, J. Christian; Hoffman, D.J.; Schmutz, J.A.

    2009-01-01

    Reduced populations of emperor geese (Chen canagica), a Bering Sea endemic, provided the need to assess plasma biochemistry values as indicators of population health. A precursory step to such an investigation was to evaluate patterns of variability in plasma biochemistry values among age, sex, and reproductive period. Plasma from 63 emperor geese was collected on their breeding grounds on the Yukon-Kuskokwim Delta in western Alaska, USA. The geese sampled included 18 incubating adult females captured, in mid June, on their nests by using bow nets, and 30 adults and 15 goslings captured in corral traps in late July and early August, when the adults were molting their wing feathers and the goslings were 5-6 weeks old. Plasma was evaluated for 15 biochemical parameters, by comparing results among age, sex, and sampling period (incubation versus wing-feather molt). Ten of the 15 biochemical parameters assayed differed among adults during incubation, the adults during molt, and the goslings at molt, whereas sex differences were noted in few parameters.

  15. Comment on “Chen et al., Fabrication and photovoltaic conversion enhancement…”, Electrochimica Acta, 2014

    Science.gov (United States)

    Valentic, Lara; Gorji, Nima E.

    2015-09-01

    In a recent article, Chen et al. [Electrochimica Acta, 2014, 130: 279] presented their fabrication and characterization results on a graphene/n-Si solar cell where the Au nanoparticles were inserted in graphene to increase its optical and electrical properties. The higher efficiency of the device was attributed to increased conductivity of graphene after doping with Au nanoparticles. However, the knowledge in the field of Schottky diode solar cells relates this to increased band bending at the junction. Also, to explain the instability behaviour, they concluded that the growth of silicon oxide on the Si surface or oxygen adsorption on the window layer resulted in the device performance increasing initially and decreasing in the end. However, this instability seems to be due to variation in series resistance reduced at the beginning because of slightly lowered Fermi level and increased at the end by the self-compensation by deep in-diffusion of Au nanoparticles into n-Si layer. We also propose that inserting a very thin p-type layer at the junction will enhance the carrier collection and performance of this device.

  16. Debris flow run off simulation and verification ‒ case study of Chen-You-Lan Watershed, Taiwan

    Directory of Open Access Journals (Sweden)

    M.-L. Lin

    2005-01-01

    Full Text Available In 1996 typhoon Herb struck the central Taiwan area, causing severe debris flow in many subwatersheds of the Chen-You-Lan river watershed. More severe cases of debris flow occurred following Chi-Chi earthquake, 1999. In order to identify the potentially affected area and its severity, the ability to simulate the flow route of debris is desirable. In this research numerical simulation of debris flow deposition process had been carried out using FLO-2D adopting Chui-Sue river watershed as the study area. Sensitivity study of parameters used in the numerical model was conducted and adjustments were made empirically. The micro-geomorphic database of Chui-Sue river watershed was generated and analyzed to understand the terrain variations caused by the debris flow. Based on the micro-geomorphic analysis, the debris deposition in the Chui-Sue river watershed in the downstream area, and the position and volume of debris deposition were determined. The simulated results appeared to agree fairly well with the results of micro-geomorphic study of the area when not affected by other inflow rivers, and the trends of debris distribution in the study area appeared to be fairly consistent.

  17. Effect of feeding and fasting on excess post-exercise oxygen consumption in juvenile southern catfish (Silurus meridionalis Chen).

    Science.gov (United States)

    Fu, Shi-Jian; Cao, Zhen-Dong; Peng, Jiang-Lan

    2007-03-01

    The impact of feeding (fed to satiation, 13.85% body mass) on excess post-exercise oxygen consumption (EPOC, chasing for 2.5 min) was investigated in juvenile southern catfish (Silurus meridionalis Chen) (38.62-57.55 g) at 25. Cutlets of freshly killed loach species without viscera, head and tail were used as the test meal, and oxygen consumption (VO(2)) was adjusted to a standard body mass of 1 kg using a mass exponent of 0.75. Resting VO(2) increased significantly above fasting levels (49.89 versus 148.25 mg O(2) h(-)(1)) in 12 h postprandial catfish. VO(2) and ventilation frequency (V(f)) both increased immediately after exhaustive exercise and slowly returned to pre-exercise values in all experimental groups. The times taken for post-exercise VO(2) to return to the pre-exercise value were 20, 25 and 30 min in 12 h, 60 h and 120 h postprandial catfish, respectively. Peak VO(2) levels were 257.36+/-6.06, 219.32+/-6.32 and 200.91+/-5.50 mg O(2) h(-1) in 12 h, 60 h and 120 h postprandial catfish and EPOC values were 13.85+/-4.50, 27.24+/-3.15 and 41.91+/-3.02 mg O(2) in 12 h, 60 h and 120 h postprandial southern catfish, respectively. There were significant differences in both EPOC and peak VO(2) during the post-exercise recovery process among three experimental groups (pcatfish, (2) both the digestive process and exercise (also the post-exercise recovery process) were curtailed under postprandial exercise, (3) the change of V(f) was smaller than that of VO(2) during the exhaustive exercise recovery process, (4) for a similar increment in VO(2), the change in V(f) was larger during the post-exercise process than during the digestive process.

  18. Development of microsatellite loci exhibiting reverse ascertainment bias and a sexing marker for use in Emperor Geese (Chen canagica)

    Science.gov (United States)

    Gravley, Meg C.; Sage, George K.; Schmutz, Joel A.; Talbot, Sandra

    2017-01-01

    The Alaskan population of Emperor Geese (Chen canagica) nests on the Yukon–Kuskokwim Delta in western Alaska. Numbers of Emperor Geese in Alaska declined from the 1960s to the mid-1980s and since then, their numbers have slowly increased. Low statistical power of microsatellite loci developed in other waterfowl species and used in previous studies of Emperor Geese are unable to confidently assign individual identity. Microsatellite loci for Emperor Goose were therefore developed using shotgun amplification and next-generation sequencing technology. Forty-one microsatellite loci were screened and 14 were found to be polymorphic in Emperor Geese. Only six markers – a combination of four novel loci and two loci developed in other waterfowl species – are needed to identify an individual from among the Alaskan Emperor Goose population. Genetic markers for identifying sex in Emperor Geese were also developed. The 14 novel variable loci and 15 monomorphic loci were screened for polymorphism in four other Arctic-nesting goose species, Black Brant (Branta bernicla nigricans), Greater White-fronted (Anser albifrons), Canada (B. canadensis) and Cackling (B. hutchinsii) Goose. Emperor Goose exhibited the smallest average number of alleles (3.3) and the lowest expected heterozygosity (0.467). Greater White-fronted Geese exhibited the highest average number of alleles (4.7) and Cackling Geese the highest expected heterozygosity (0.599). Six of the monomorphic loci were variable and able to be characterised in the other goose species assayed, a predicted outcome of reverse ascertainment bias. These findings fail to support the hypothesis of ascertainment bias due to selection of microsatellite markers.

  19. 3d-Übergangsmetalloxide: Ultradünne Schichten und Grenzflächen von MnO und NiO

    OpenAIRE

    Nagel, Mathias

    2009-01-01

    Die vorliegende Arbeit untersucht binäre Übergangsmetalloxide. Im Speziellen werden sowohl ultradünne und epitaktische Manganoxid-Schichten (MnO) auf einkristallinen Silbersubstraten als auch Grenzflächen zwischen Übergangsmetallen und Oxiden betrachtet. Strukturelle, elektronische und magnetische Eigenschaften von Übergangsmetalloxiden in dünnen Schichtsystemen sind von grundlegendem Interesse. Für Anwendungen im Bereich der magnetischen Datenspeicherung oder in der Entwicklung von Spintr...

  20. Effect of feeding on the function and structure of the digestive system in juvenile southern catfish (Silurus meridionalis Chen).

    Science.gov (United States)

    Zeng, Ling-Qing; Li, Feng-Jie; Fu, Shi-Jian; Cao, Zhen-Dong; Zhang, Yao-Guang

    2012-10-01

    Postprandial physiological and morphological responses to feeding were examined in juvenile southern catfish (Silurus meridionalis Chen) that had consumed a loach (Misgurnus anguillicaudatus Cantor) meal equivalent to 6 % of the body mass of the catfish. The gastric evacuation rate (GER) peaked at 4 h postfeeding, averaging 0.36 g food weight h(-1), at which time 14 % of the ingested meal had passed into the intestine. Less than 10 % of the ingested meal remained in the stomach at 24 h postfeeding. Pepsin activity peaked at 8 h postfeeding, reaching a level approximately twofold higher than the prefeeding level. Pancreatic trypsin activity peaked at 16 h postfeeding, reaching a level 4.5-fold higher than the prefeeding level. Peaks in lipase activity in both the proximal and middle intestinal segments occurred at 16 h, reaching 2.8- and 2.4-fold higher levels than the prefeeding level, respectively, while the activity in the distal intestine segment reached a level 2.9-fold higher than the prefeeding level at 24 h postfeeding. With respect to amylase activity, only the middle intestinal segment exhibited a change, first an increase and then a decrease, after feeding. Feeding also triggered an approximately 200 % increase in the metabolic rate and resulted in 44.6 kJ kg(-1) being expended on specific dynamic action, equivalent to 16.1 % of the meal's energy. In terms of organ size, the wet mass of the liver increased by 11 % at 24 h postfeeding, whereas the wet mass of the pancreas did not change. Except for a decrease in the thickness of the submucosa in the middle intestinal segment, the thickness of the intestinal fold, mucosa, submucosa, muscularis and serosa of each intestinal segment did not change significantly with feeding. These results suggest that the continuum of physiological responses observed with respect to metabolic increases, GER, regulation of pancreatic and intestinal digestive enzyme activities and liver wet mass to feeding

  1. Chinese Commission of Science Technology and Industry for National Defense Senior Vice Minister CHEN Qiufa exchanging gifts at luncheon and signing the Guest Book on 1st November 2007 with CERN Director-General R. Aymar.

    CERN Multimedia

    Maximilien Brice

    2007-01-01

    Chinese Commission of Science Technology and Industry for National Defense Senior Vice Minister CHEN Qiufa exchanging gifts at luncheon and signing the Guest Book on 1st November 2007 with CERN Director-General R. Aymar.

  2. 6 June 2012 - Chinese Nanjing University President J.Chen in the ATLAS visitor centre with Member of the ATLAS Collaboration I. Wingerter and International Relations Office Adviser E. Tsesmelis. M. Qi, Nanjing University and ATLAS Collaboration, accompanies the delegation.

    CERN Multimedia

    Maximilien Brice

    2012-01-01

    6 June 2012 - Chinese Nanjing University President J.Chen in the ATLAS visitor centre with Member of the ATLAS Collaboration I. Wingerter and International Relations Office Adviser E. Tsesmelis. M. Qi, Nanjing University and ATLAS Collaboration, accompanies the delegation.

  3. Modification of Sako-Wu-Prausnitz equation of state for fluid phase equilibria in polyethylene-ethylene systems at high pressures

    Directory of Open Access Journals (Sweden)

    F. Gharagheizi

    2006-09-01

    Full Text Available In order to model phase equilibria at all pressures, it is necessary to have an equation of state. We have chosen the Sako-Wu-Prausnitz cubic equation of state, which had shown some promising results. However, in order to satisfy our demands, we had to modify it slightly and fit new pure component parameters. New pure component parameters have been determined for ethylene and the n-alkane series, using vapor pressure data, saturated liquid volume and one-phase PVT-data. For higher n-alkanes, where vapor pressure data are poor or not available, determination of the pure component parameters was made in part by extrapolation and in part by fitting to one-phase PVT-data. Using one-fluid van der Waals mixing rules, with one adjustable interaction parameter, good correlation of binary hydrocarbon system was obtained, except for the critical region. The extension of the equation of state to polyethylene systems is covered in this work. Using the determined parameters, flash and cloud point calculations were performed, and treating the polymer as polydisperse. The results fit data well.

  4. Inhibition of Neoplastic Transformation and Chemically-Induced Skin Hyperplasia in Mice by Traditional Chinese Medicinal Formula Si-Wu-Tang

    Directory of Open Access Journals (Sweden)

    Mandy M. Liu

    2017-03-01

    Full Text Available Exploring traditional medicines may lead to the development of low-cost and non-toxic cancer preventive agents. Si-Wu-Tang (SWT, comprising the combination of four herbs, Rehmanniae, Angelica, Chuanxiong, and Paeoniae, is one of the most popular traditional Chinese medicines for women’s diseases. In our previous studies, the antioxidant Nrf2 pathways were strongly induced by SWT in vitro and in vivo. Since Nrf2 activation has been associated with anticarcinogenic effects, the purpose of this study is to evaluate SWT’s activity of cancer prevention. In the Ames test, SWT demonstrated an antimutagenic activity against mutagenicity induced by the chemical carcinogen 7,12-dimethylbenz(aanthracene (DMBA. In JB6 P+ cells, a non-cancerous murine epidermal model for studying tumor promotion, SWT inhibited epidermal growth factor (EGF-induced neoplastic transformation. The luciferase reporter gene assays demonstrated that SWT suppressed EGF-induced AP-1 and TNF-α-induced NF-κB activation, which are essential factors involved in skin carcinogenesis. In a DMBA-induced skin hyperplasia assay in ‘Sensitivity to Carcinogenesis’ (SENCAR mice, both topical and oral SWT inhibited DMBA-induced epidermal hyperplasia, expression of the proliferation marker Proliferating cell nuclear antigen (PCNA, and H-ras mutations. These findings demonstrate, for the first time, that SWT prevents tumor promoter and chemical-induced carcinogenesis in vitro and in vivo, partly by inhibiting DNA damage and blocking the activation of AP-1 and NF-κB.

  5. Contamination and Human Health Risk Assessment of Polycyclic Aromatic Hydrocarbons (PAHs) in Oysters After the Wu Yi San Oil Spill in Korea.

    Science.gov (United States)

    Loh, Andrew; Yim, Un Hyuk; Ha, Sung Yong; An, Joon Geon; Kim, Moonkoo

    2017-07-01

    After the collision of the Singapore-registered oil tanker M/V Wu Yi San into the oil terminal of Yeosu, Korea on January 31, 2014, approximately 900 m3 of oil and oil mixture were released from the ruptured pipelines. The oil affected more than 10 km of coastline along Gwangyang Bay. Emergency oil spill responses recovered bulk oil at sea and cleaned up the stranded oil on shore. As part of an emergency environmental impact assessment, region-wide monitoring of oil contamination in oyster had been conducted for 2 months. Highly elevated concentrations of polycyclic aromatic hydrocarbons (PAHs) were detected at most of the spill affected sites. Four days after the spill, the levels of PAHs in oysters increased dramatically to 627-81,000 ng/g, the average of which was 20 times higher than those found before the spill (321-4040 ng/g). The level of PAHs in these oysters increased until 10 days after the spill and then decreased. Due to the strong tidal current and easterly winter winds, the eastern part of the Bay-the Namhae region-was heavily contaminated compared with other regions. The accumulation and depuration of spilled oil in oyster corresponded with the duration and intensity of the cleanup activities, which is the first field observation in oil spill cases. Human health risk assessments showed that benzo[a]pyrene equivalent concentrations exceeded levels of concern in the highly contaminated sites, even 60 days after the spill.

  6. Comment on "Current separation and upwelling over the southeast shelf of Vietnam in the South China Sea" by Chen et al.

    Science.gov (United States)

    Dippner, Joachim W.; Bombar, Deniz; Loick-Wilde, Natalie; Voss, Maren; Subramaniam, Ajit

    2013-03-01

    In a recent paper, Chen et al. (2012) showed that the offshore current in front of the Vietnamese upwelling area in the South China Sea (SCS) is caused by an encounter of southward buoyancy-driven coastal current and tidal rectified currents from the southwest. These findings seem not in agreement with in-situ observations. The mechanism for the formation of the offshore current has its origin in the inter-annual variability of atmospheric forcing. El Niño Southern Oscillation events modulate the northern position of Inter-Tropical Convergence Zone and the intensity of both, SW monsoon and upwelling. Strong upwelling influences the spatial distribution of characteristic water masses which results in a blocking of the near coastal northward propagation of the plume of River Mekong and the formation of an offshore current.

  7. Overview of the KwaZulu-Natal sardine run | van der Lingen | African ...

    African Journals Online (AJOL)

    This paper provides an introduction to, and overview of, the natural phenomenon known as the KwaZulu-Natal sardine run. Previous literature on this topic and hypotheses about the reasons why, and the mechanisms how, the run occurs are briefly synthesised and described. Papers contributing to this suite that detail more ...

  8. The influence of essential oils from Xiang-Fu-Si-Wu Decoction on its non-volatile components and its application for pharmacokinetics in normal rats.

    Science.gov (United States)

    Pan, Ying; Qian, Dawei; Liu, Pei; Zhang, Yang; Zhu, Zhenhua; Zhang, Li; Duan, Jin-Ao

    2017-08-15

    Xiang-Fu-Si-Wu Decoction (XFSWD) has been used to treat gynecology diseases in clinical practice for hundreds of years in China, especially for primary dysmenorrheal of QiZhi Type. In previous researches, both essential oils (XEO) and non-volatile components (NXEO) extracted from XFSWD showed significant pharmacological activities, but the influence of XEO on NXEO was unclear. The purpose of this paper was to develop a validated analytical method for simultaneous determination of ten components including Vanillic acid, Ferulic acid, Caffeic acid, Gallic acid, Paeoniflorin, Albiflorin, Tetrahydropalmatine, Protopine, Berberine and Tetrahydrocolumbamine, and to compare the pharmacokinetic parameters of these components to illustrate the influences of XEO on NXEO in normal rats. After being extracted by methanol (1:3, v/v), the plasma samples were analyzed with Clarithromycin (IS 1 ) and Chloramphenicol (IS 2 ) as mixed internal standard (IS). Then the analytes were separated on a ACQUITY UPLC BEH C 18 (100×2.1mm, 1.7μm) column with gradient mobile phase (containing 0.1% formic acid aqueous solution and acetonitrile) at a flow rate of 0.4mL/min. All analytes and mixed IS were performed on an electrospray ionization source (ESI) using multiple-reaction monitoring (MRM) with positive and negative ionization mode. The calibration curves of all the analytes showed good linearity (r >0.99), and the lower limits of quantification (LLOQ) were 0.66-46.88ng/mL. The intra- and inter-day precisions ranged 1.24-12.45% and 2.49-13.24% for all the analytes. The mean extraction recoveries of the analytes were in the range of 73.10-93.71% and the average matrix effects were within 82.39-93.18%. The validated method has been fully applied to compare the pharmacokinetic parameters of ten components in rat plasma after oral administration of NXEO, NXEO+β-cyclodextrin (β-CD), NXEO+XEO, and NXEO+β-XEO (the inclusion of XEO by β-CD). It was found that the area under the concentration

  9. 吴燕平分期治疗经期延长的经验%Experience of Wu Yanping in Treating Prolonged Menstruation with the Method of the Installment of Governance

    Institute of Scientific and Technical Information of China (English)

    左海红; 吴燕平

    2013-01-01

    [目的]总结吴燕平教授分期治疗经期延长的经验.[方法]分别从病因病机、辨证与辨病结合、分期论治等方面论述吴燕平教授治疗经期延长的经验.[结果]本病病机多为“虚、热、瘀”,与肾和冲任关系密切.根据以上病机,提倡辨证与辨病相结合,西医明确病因,中医辨证论治,分期治疗.用药组方多从脾肾入手,攻补兼施,标本兼治.[结论]吴燕平教授采用分期论治,健脾益肾的综合疗法,调整月经周期,调节内分泌,缩短经期,疗效明显.%[Objecrive]The article summarized and discoursed the experience of professor Wu Yanping treating prolonged menstruation with the method of the installment of governance. [Method] Discoursed the experience of professor Wu Yanping treating prolonged menstruation from cause of disease,ptho-genesis.combination of syndrome differentiation and disease.installment of governance and so on.[Result]The cause of disease and pthogenesis are "debilita-tion,heat,stasis".The disease closely relates to kidney, thoroughfare and conception vessels. Professor Wu Yanping advocated the combination of syndrome differentiation and disease and installment of governance according to the cause of disease and pthogenesis.Western medicine makes the causes clear.and TCM treats disease based on syndrome differentiation.The formula mainly relates to spleen and kidney .The treatments combinate both the reinforcement and elimination,and focus on relieving both the secondary and primary symptoms. [Conclusions] Wu Yanping takes stage treatment, the comprehensive therapy of reinforcing spleen to nourish kidney, regulates endocrine and shortens menstruation, with good cure effect.

  10. [Reiner Nürnberg, Ekkehard Höxtermann, Martina Voigt. Elisabeth Schiemann 1881-1972. Vom AußBruch der Genetik und der Frauen in den UmBrüchen des 20. Jahrhunderts] / Monika von Hirschheydt

    Index Scriptorium Estoniae

    Hirschheydt, Monika von

    2015-01-01

    Arvustus: Nürnberg, Reiner, Höxtermann, Ekkehard, Voigt, Martina. Elisabeth Schiemann 1881-1972. Vom AußBruch der Genetik und der Frauen in den UmBrüchen des 20. Jahrhunderts. Beiträge eines Symposiums zum 200. Gründungsjubiläum der Humboldt-Universität Berlin. Rangsdorf: Basilisken-Presse 2014

  11. Héritages mortifères. Rupture dans/de la filiation chez Ying Chen et Jane Sautière

    Directory of Open Access Journals (Sweden)

    Anne-Marie Parent

    2012-01-01

    Full Text Available Les récits Nullipare (2008 de Jane Sautière et Un enfant à ma porte (2008 de Ying Chen mettent tous deux en scène des femmes qui se révèlent incapables d’être mères. Le présent article montre que cette incapacité à avoir un enfant vient du fait que pour les deux narratrices, la filiation est liée à la mort, à la perte et à l’absence ; dans les deux textes, un héritage mortifère fait rupture et empêche la filiation de se poursuivre. Jane Sautière’s Nullipare (2008 and Ying Chen’s Un enfant à ma porte (2008 both portray a woman unable to become a mother. This article shows that the inability to have a child stems from the fact that, for the narrators of each work, filiation is linked to death, to loss, and to absence; in the two texts, a deadly legacy breaks the line of filiation and prevents its continuation.

  12. "Is political behavior a viable coping strategy to perceived organizational politics? Unveiling the underlying resource dynamics": Correction to Sun and Chen (2017).

    Science.gov (United States)

    2017-10-01

    Reports an error in "Is Political Behavior a Viable Coping Strategy to Perceived Organizational Politics? Unveiling the Underlying Resource Dynamics" by Shuhua Sun and Huaizhong Chen (Journal of Applied Psychology, Advanced Online Publication, May 22, 2017, np). In the article, Table 1 contained a formatting error. Correlation coefficient values in the last four cells of column 6 were misplaced with correlation coefficient values in the last four cells of column 7. All versions of this article have been corrected. (The following abstract of the original article appeared in record 2017-22542-001.) We conduct a theory-driven empirical investigation on whether political behavior, as a coping strategy to perceived organizational politics, creates resource trade-offs in moderating the relationship between perceived organizational politics and task performance. Drawing on conservation of resources theory, we hypothesize that political behavior mitigates the adverse effect of perceived organizational politics on task performance via psychological empowerment, yet exacerbates its adverse effect on task performance via emotional exhaustion. Three-wave multisource data from a sample of 222 employees and their 75 supervisors were collected for hypothesis testing. Findings supported our hypotheses. Our study enhances understandings of the complex resource dynamics of using political behavior to cope with perceived organizational politics and highlights the need to move stress-coping research from a focus on the stress-buffering effect of coping on outcomes to a focus on the underlying competing resource dynamics. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

  13. Paragonimus heterotremus Chen and Hsia (1964), in Vietnam: a molecular identification and relationships of isolates from different hosts and geographical origins.

    Science.gov (United States)

    Le, Thanh H; Van De, Nguyen; Blair, David; McManus, Donald P; Kino, Hideto; Agatsuma, Takeshi

    2006-04-01

    Paragonimus heterotremus Chen and Hsia (1964), and paragonimiasis caused by this species is a newly detected disease in Vietnam. Twelve samples of Paragonimus (Platyhelminthes: Trematoda: Digenea: Paragonimidae) from different life-stages (eggs, miracidia, metacercariae, adults from natural and experimental hosts) and host species (crab, dog, cat and human) were collected in different geographical locations in Vietnam. DNA sequences were obtained from each for partial mitochondrial cytochrome c oxidase subunit 1 (cox1) (387 bp) and the entire second ribosomal internal transcribed spacer (ITS-2) (361 bp). The ITS-2 sequences were identical among all specimens, including those previously reported in GenBank. For cox1, there were sequence differences between specimens from Vietnam (four provinces, different locations) and those from Guangxi (China) and Saraburi (Thailand). Phylogenetic trees inferred from cox1 and ITS-2 sequences using sequence data for 15 P. heterotremus and for other Paragonimus spp. revealed that all P. heterotremus originating from Vietnam, Thailand and China form a distinct group. This information also confirms the identity of the Vietnamese specimens as P. heterotremus.

  14. Measuring the impact of a 3D simulation experience on nursing students' cultural empathy using a modified version of the Kiersma-Chen Empathy Scale.

    Science.gov (United States)

    Everson, Naleya; Levett-Jones, Tracy; Lapkin, Samuel; Pitt, Victoria; van der Riet, Pamela; Rossiter, Rachel; Jones, Donovan; Gilligan, Conor; Courtney-Pratt, Helen

    2015-10-01

    To determine the effect of immersive 3D cultural simulation on nursing students' empathy towards culturally and linguistically diverse patients. Accelerated globalisation has seen a significant increase in cultural diversity in most regions of the world over the past forty years. Clinical encounters that do not acknowledge cultural factors contribute to adverse patient outcomes and health care inequities for culturally and linguistically diverse people. Cultural empathy is an antecedent to cultural competence. Thus, appropriate educational strategies are needed to enhance nursing students' cultural empathy and the capacity to deliver culturally competent care. A one-group pretest, post-test design was used for this study. The simulation exposed students to an unfolding scene in a hospital ward of a developing county. A convenience sample of second-year undergraduate nursing students (n = 460) from a semi-metropolitan university in Australia were recruited for the study. Characteristics of the sample were summarised using descriptive statistics. T-tests were performed to analyse the differences between pre- and post simulation empathy scores using an eight item modified version of the Kiersma-Chen Empathy Scale. Students' empathy towards culturally and linguistically diverse patients significantly improved after exposure to the 3D simulation experience. The mean scores for the Perspective Taking and Valuing Affective Empathy subscales also increased significantly postsimulation. The immersive 3D simulation had a positive impact on nursing students' empathy levels in regards to culturally and linguistically diverse groups. Research with other cohorts and in other contexts is required to further explore the impact of this educational approach. Immersive cultural simulation experiences offer opportunities to enhance the cultural empathy of nursing students. This may in turn have a positive impact on their cultural competence and consequently the quality of care they

  15. Un imaginaire dévoilé/déphasé. Stratégies narratives et mémoire culturelle dans le roman 54 des Wu Ming

    Directory of Open Access Journals (Sweden)

    Matteo Martelli

    2015-02-01

    Full Text Available This essay analyses the narrative strategies through which cultural memory is portrayed in 54, a novel in which Wu Ming (a collective of four Italian fiction writers suggests a literary mapping of the Fifties. This is obtained by a recovery of a shared imaginary tradition which is close to the reader, mixing fictional and historical characters, films, books, different genres of popular literature. Nevertheless, the rewriting of these imaginary traditions involves their displacement, a presentation which is constantly created from an unusual point of view. Thus, shifting the image of what is already known, the text inquires into several modalities of a questioning about cultural memory and its redefinition in relation to contemporary culture. By focusing on these elements, this study proposes an analysis which starts from the construction of the characters, the role of suspense and the adoption of multiple traditions of novel writing.

  16. Retracted: Sirt3 activation attenuated oxidized low-density lipoprotein-induced human umbilical vein endothelial cells' apoptosis by sustaining autophagy by Luo, X, Yang, Z, Zheng, S, Cao, Y and Wu, Y.

    Science.gov (United States)

    2017-08-01

    The above article, published online on 05 May 2014 in Wiley Online Library (http://onlinelibrary.wiley.com/doi/10.1002/cbin.10291/full), has been retracted by agreement between the authors, the journal Editor, Sergio Schenkman, and John Wiley & Sons Ltd. The retraction has been agreed because the authors discovered that the results of section 3 in this paper were irreproducible. In addition, Zhiqiang Yang, a co-author, states conflict of interest in this paper. The authors and publisher apologize for any inconvenience. Reference Luo X, Yang Z, Zheng S, Cao Y, Wu Y (2014) Sirt3 activation attenuated oxidized low-density lipoprotein induced human umbilical vein endothelial cells' apoptosis by sustaining autophagy. Cell Biol Int, https://doi.org/10.1002/cbin.10291. © 2017 International Federation for Cell Biology.

  17. The effects of dissolved oxygen level on the metabolic interaction between digestion and locomotion in juvenile southern catfish (Silurus meridionalis Chen).

    Science.gov (United States)

    Zhang, Wei; Cao, Zhen-Dong; Peng, Jiang-Lan; Chen, Bo-Jian; Fu, Shi-Jian

    2010-11-01

    To investigate the effect of dissolved oxygen level ([O(2)]) on maintenance metabolism, feeding metabolism, aerobic swimming performance and their metabolic interaction in juvenile southern catfish (Silurus meridionalis Chen), we measured the following: (1) the resting oxygen consumption rate (MO(2rest)) over a range of water [O(2)] and from this we calculated the critical oxygen tension (P(crit)) of fasting fish; (2) the postprandial MO(2) response (10% body mass meal size) at water [O(2)] of 1, 2, 4 and 8mgO(2)L(-1); and (3) the swimming performance of fasting and digesting fish at water [O(2)] of 1, 2, 4 and 8mgO(2)L(-1) at 25 degrees C. The MO(2rest) remained constant over a broad range of water [O(2)] but then dropped markedly upon reaching the P(crit) (16.4% saturation). Hypoxic groups presented lower peak postprandial MO(2) (MO(2peak)) (1mgO(2)L(-1) group), larger energy expenditure and longer digestive process (both 1 and 2mgO(2)L(-1)) than those of normoxic groups. Both critical swimming speed (U(crit)) and the active metabolic rate (MO(2active)) of fasting fish remained unchanged over a decrease in water [O(2)] from 8 to 4mgO(2)L(-1) and then decreased significantly with further decreases in water [O(2)]. These parameters in fed fish showed a pronounced decrease as water [O(2)] decreased from 8 to 1mgO(2)L(-1). Feeding caused a significantly lower U(crit) in the 2mgO(2)L(-1) water [O(2)] group, a significantly higher MO(2active) in both the 2 and 8mgL(-1) water [O(2)] groups and a significantly higher metabolic scope (MO(2active)-MO(2rest)) in both the 2 and 4mgO(2)L(-1) water [O(2)] groups compared to fasting fish. The MO(2) increased greatly with swimming speed in the higher water [O(2)] groups, whereas it leveled off as swimming speeds approached the U(crit) in the lower water [O(2)] groups. Within all water [O(2)] groups, feeding caused a higher MO(2) compared to fasting fish when fish swam at the same speeds, except in the 1mgO(2)L(-1) group. This

  18. Two phases of droplet evaporation during plasma arc spraying: reply to Chen's comment about the 'rocket' effect under conditions of thermal plasma spraying

    Energy Technology Data Exchange (ETDEWEB)

    Nemchinsky, V A [Key College, 225 Dania Beach Blvd, Dania Beach, FL 33040 (United States)

    2007-07-07

    The heating history of a droplet during its flight can be divided into two phases: (a) the initial phase when evaporation, although it occurs, does not change the heat balance of the droplet much (the case considered in our previous paper and (b) the final phase when the cooling due to evaporation balances the heat flux from the plasma. The later phase is considered in Chen's comment. In our reply, a very straightforward consideration demonstrates that even in the final phase of the droplet flight, the 'rocket' effect can be significant. (reply)

  19. Struktur und Funktion von S-Layern acidophiler Bakterien und Archaeen, ihre Rolle bei der Pyrit-Oxidation sowie die Adhäsion an Oberflächen

    OpenAIRE

    Klingl, Andreas

    2011-01-01

    Anhand physiologischer und morphologischer Untersuchungen an den γ-Proteobakterienstämmen SP5/1 und HV2/2 sollten Einsichten über deren Einordnung innerhalb der Gattung Acidithiobacillus erlangt werden. Zusätzlich waren die Charakterisierung der Surface Layer des Acidithiobacillus-Isolates SP5/1 und von M. sedula TH2, sowie deren mögliche Funktionen und ihre Rolle bei der Interaktion mit Oberflächen von besonderem Interesse. Angesichts der Ergebnisse, welche aus der Sequenzierung der 16S ...

  20. Study to establish Ojeok-San (Five Accumulation Powder: wu ji san) administration criteria and a questionnaire to evaluate the holistic effects of Ojeok-San on patients with low back pain.

    Science.gov (United States)

    Kim, Eun-Jung; Nam, Dongwoo; Ahn, Byung-Jin; Lee, Seung-Deok; Lee, Jae-Dong; Kim, Kap-Sung

    2013-11-01

    The study objectives were to establish ojeok-san (Five Accumulation Powder: wu ji san) administration criteria and a questionnaire to evaluate the holistic effects of ojeok-san on patients with low back pain (LBP). Texts and literatures, recommended by specialists, were searched to gather ojeok-san-related symptoms. Then, the opinions of Oriental medicine doctors (OMDs) practicing in Seoul were surveyed to ask which symptoms they consider the most in clinical practice. Based on the survey, selection of potential items for the questionnaire was made. The final version was established based on the results of the survey and Delphi process of musculoskeletal diseases specialists. In order to evaluate the reliability and validity of the newly developed assessment tool (Ojeok-san Low Back Questionnaire: OLQ), patients with chronic LBP were recruited. OLQ and other tools such as visual analogue scale, numeric rating scale, Roland-Morris Disability Questionnaire, Modified-Modified Schober test, and 36-Item Short Form Health Survey were applied to the subjects in a 2-week interval. Test-retest reliability, internal consistency, and convergent and discrimination validity were assessed. A total of 90 potential items were generated by the research team. One hundred and two (102) OMDs fully replied to the survey. Based on the survey results, 34 items were initially selected as potential items. Through Delphi method of experts, 10 top items, rated more than 5 points on a scale of 10, were finally established. The 10 items were each established as a response scale of 0-10 (0 as no symptom and 10 as the most excessive form of symptom). Based on the above stages, an initial OLQ was established and used in the evaluation phase. The validity and reliability of OLQ assessment results showed high test-retest reliability, intraclass correlation coefficient, and internal consistency. The newly developed Ojeok-san administration criteria and questionnaire may be a promising tool for

  1. Claire Shen Hsiu-chen, L’Encre et l’Ecran. A la recherche de la stylistique cinématographique chinoise, Hou Hsiao-hsien et Zhang Yimou (Ink and the Screen : In Search of Chinese Film Stylistics, Hou Hsiao-hsien and Zhang Yimou)

    OpenAIRE

    Reynaud, Bérénice

    2006-01-01

    Reading Claire Shen Hsiu-chen gave me the impression several times of discovering a kindred spirit, so closely does the first part of her book confirm some of my analyses. Like her, I sought to scrutinise the Chinese pictorial and cosmological tradition in order to find the origins of Hou Hsiao-hsien’s directing, which is both specific to an original author and rooted in Taiwanese history and tradition. We have read the same texts (those of François Chen, Noel Burch, Michel Chion and Yeh Yueh...

  2. Chinese Commission of Science Technology and Industry for National Defense Senior Vice Minister CHEN Qiufa visiting ALICE experiment on 1st November 2007 with CERN Director-General R. Aymar and Adviser J.-P. Revol. Thursday, 1st and Friday, 2nd November 2007

    CERN Multimedia

    Maximilien Brice

    2007-01-01

    Chinese Commission of Science Technology and Industry for National Defense Senior Vice Minister CHEN Qiufa visiting ALICE experiment on 1st November 2007 with CERN Director-General R. Aymar and Adviser J.-P. Revol. Thursday, 1st and Friday, 2nd November 2007

  3. Designing Robust and Resilient Tactical MANETs

    Science.gov (United States)

    2014-09-25

    Multipath Wireless Network, IEEE ISIT 2012. 01-JUL-12, . : , Tzong-Chen Wu, Chia-Hsin Owen Chen, Chung-Wei Chen, Cynthia Kuo, Yan-Hao Lai, Jonathan...Communications. 01-MAY-08, . : , Qing Li , Meiyuan Zhao , Jesse Walker, Yih-Chun Hu, Adrian Perrig, Wade Trappe. SEAR: A Secure Efficient Ad Hoc On Demand Routing

  4. Determination and Distribution Study of Pogostone in Rat Tissues by ...

    African Journals Online (AJOL)

    Determination and Distribution Study of Pogostone in Rat Tissues by Ultra-Fast Liquid Chromatography. HM Chen, L Wang, XL Wu, CW Li, YL Xie, YH Liu, YZ Liang, XY Chen, XP Lai, JN Chen, YC Li, ZR Su ...

  5. MARGA_Chen et al_2016

    Data.gov (United States)

    U.S. Environmental Protection Agency — These data describe the chromatography characteristics of the MARGA instrument software as compared to an alternative, independent technique for chromatogram...

  6. Immunogenicity of novel sulfadimethoxide conjugates | Chen ...

    African Journals Online (AJOL)

    SDM antibodies are useful for the detection of residual SDM in foods, feeds and biological fluids by ELISA. In this study, we show that SDM is immunogenic in rabbits when it is conjugated with soy 11S globulin or with β- amylase. Rabbit ...

  7. Reinigung superhydrophober Oberflächen

    OpenAIRE

    Dallmann, Silke

    2011-01-01

    The unique surface structure of the lotus leaf in combination with hydrophobic epicuticular wax crystalloids results in extreme water repellency and self-cleaning properties. In recent years biomimetic superhydrophobic surfaces have been fabricated by mimicking the structure of the lotus leaf. The biggest problem of the fine surface roughness is the sensitivity to oily contaminants and mechanical stress which limit the application of technical superhydrophobic sur...

  8. Blazar Sequence in Fermi Era Liang Chen

    Indian Academy of Sciences (India)

    HSP) blazars indicates that this simple analysis should be problematic. So does the discovery of numerous low-power-low-sychrotron-peaked (LP-LSP) blazars. If a blazar has a less beaming jet, its synchrotron bump should peak at lower fre- quency and lower power. Therefore, beaming effect may account for HP-HSP and.

  9. 羅振玉日本教育考察與晚清學制制定的關係 Chen-Yu Lo’ Educational Visit to Japan and the Drafting of School Systems in Late Ch’ing

    Directory of Open Access Journals (Sweden)

    周愚文 Yu-Wen Chou

    2015-03-01

    Full Text Available 羅振玉早年關心農業與教育,曾辦東文學社教日語,出版《農報》,譯農書,故受張之洞聘請,掌湖北農務局及農學堂。1901年辛丑詔改各省書院為學堂,獲張之洞與劉坤一共薦率員考察日本教育兩個月。先後訪談重要政教人物,參訪東京、京都、奈良等地學校24所,蒐購中小學教科書及理化器材。因時短、行程緊湊及語言限制,未讀前人考察紀錄,自認收穫有限。返國後,他曾獲張之洞五次接見,並命向鄂官員講說教育。又代張之洞擬教育制度草案欲與劉督會奏,但因劉屬官反對遂寢。他遂出版訪日紀錄及資料,並發表〈學制私議〉等文建議興學,部分被鄂參採。當朝廷擬訂壬寅及癸卯學制時,羅未參與而資料只供參考,但章程規定中小學堂學科八科及小學堂以學國語為主等二項,可能與其建議有關。隨行陳毅曾譯日教育法規並兩度遊日,起草奏定章程時,當不會只憑文獻閉門造車,但主政者乏直接經驗,故教育借用日制時難盡合國情。 Chen-Yu Lo had concern about agriculture and education. He was invited by Governor-General Chih-tung Chang to preside over the Agriculture Department of Hubei and its Agriculture School. In 1901, ordered by Chang and Governor-General Kun-I Liu, he led a group of delegates to visit educational institutions in Japan. Within two months, he discussed with influential politicians and educators, visited 24 schools in Tokyo, Kyoto, and Nara, and purchased elementary and secondary school textbooks and laboratory equipments. When he returned, he had five meetings with Chang, and lectured on education for Hubei officials. On behalf of Chang, Lo had drafted a new educational system, and it was to be presented to the throne by Chang and Liu, however, the proposal was withdrawn due to the objections of Liu’s subordinates. Later, Lo made the collected

  10. Reply to the comment by Wu et al. (2016) on "Behavior of Re and Os during contact between an aqueous solution and oil: Consequences for the application of the Re-Os geochronometer to petroleum" [Geochim. Cosmochim. Acta 158 (2015) 1-21

    Science.gov (United States)

    Reisberg, Laurie; Michels, Raymond; Mahdaoui, Fatima

    2016-08-01

    We reply here to the questions raised by Wu et al. concerning the results published by Mahdaoui et al. (2015). This paper describes experiments in which aqueous solutions containing ReO4- and OsCl62- were brought in contact with natural oils at various ranges of concentration, time and temperature. The main observation is that the transfer of Re and Os to oils is very efficient under all experimental conditions. Wu et al. argue that thermodynamic equilibrium was not achieved in these experiments as apparent partition coefficients are inconsistent. They conclude that the experiments were flawed by possible leaking of reactors and that the conclusions by Mahdaoui et al. (2015) were not justified. In the following reply we explain that Mahdaoui et al. (2015) never claimed that thermodynamic equilibrium was achieved. Any calculations or considerations in this context are therefore meaningless. We recall the objectives of our publication, which were to experimentally test the behavior of ReO4- and OsCl6- (two plausible chemical forms of Re and Os in deep aquifers of petroleum systems) in aqueous solution-oil systems. To our knowledge these are the first experiments of their kind. The parameters that could influence the precision and reproducibility of our results were discussed in detail in Mahdaoui et al. (2015). The essential point is that all 60 of the experiments provide evidence of substantial transfer of Re and Os from water to oil. In contrast to what was mistakenly understood by Wu et al., the paper does not challenge the use of Re-Os to date geological events affecting petroleum. Instead, by providing a mechanism that might allow Os isotopic homogenization on a basin-wide scale, a critical step missing from most current models, it offers a possible explanation of how Re-Os geochronology in oils could potentially work. More generally, our study suggests that transfer of Re and Os from waters to oil may be an important phenomenon that should not be overlooked.

  11. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    236 Article. Silencing of HMGA2 promotes apoptosis and inhibits migration and invasion of prostate cancer cells · Zhan Shi Ding Wu Run Tang Xiang Li Renfu Chen Song Xue Chengjing Zhang Xiaoqing Sun · More Details Abstract Fulltext PDF.

  12. Identification of bacterial strains in viili by molecular taxonomy and ...

    African Journals Online (AJOL)

    Identification of bacterial strains in viili by molecular taxonomy and their synergistic effects on milk curd and exopolysaccharides production. T Chen, Q Tan, M Wang, S Xiong, S Jiang, Q Wu, S Li, C Luo, H Wei ...

  13. Frequency-domain criterion for the chaos synchronization of time ...

    Indian Academy of Sciences (India)

    domain criterion for ... Wu1 2 Yun Chen1. College of Electronic Engineering, Naval University of Engineering, Wuhan 430033, People's Republic of China; Guangzhou Naval Marine Academy, Guangzhou 510430, People's Republic of China ...

  14. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. Ding Wu. Articles written in Journal of Biosciences. Volume 41 Issue 2 June 2016 pp 229-236 Article. Silencing of HMGA2 promotes apoptosis and inhibits migration and invasion of prostate cancer cells · Zhan Shi Ding Wu Run Tang Xiang Li Renfu Chen Song Xue Chengjing Zhang ...

  15. Free vibrations of a multi-span Timoshenko beam carrying multiple ...

    Indian Academy of Sciences (India)

    Wu (2002) obtained the natural frequencies and mode shapes of the beams carrying any number of two-degrees of freedom spring-mass systems by using finite element method (FEM). Wu & Chen (2001) used the numerical assembly technique for free vibration analysis of a Timoshenko beam carrying multiple spring-mass.

  16. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Productivity and biochemical properties of green tea in response to full-length and functional fragments of HpaGXooc, a harpin protein from the bacterial rice leaf streak pathogen Xanthomonas oryzae pv. oryzicola · Xiaojing Wu Tingquan Wu Juying Long Qian Yin Yong Zhang Lei Chen Ruoxue Liu Tongchun Gao Hansong ...

  17. A Review of Cyanobacterial Odorous and Bioactive Metabolites: Impacts and Management Alternatives in Aquaculture

    Science.gov (United States)

    2008-05-06

    cyanobacterium Lyngbya majuscula. Phytochemistry 49, 2387–2389. Martin, J.F., McCoy, C.P., Greenleaf, W., Bennett, L., 1987. Analysis of 2...Bioactive natural products frommarine cyanobacteria for drug discovery. Phytochemistry 68, 954–979. Tang, J.W., Wu, Q.Y., Hao, H.W., Chen, Y., Wu, M

  18. Retraction: "Screening of candidate genes and fine mapping of drought tolerance quantitative trait loci on chromosome 4 in rice (Oryza sativa L.) under drought stress" by Nie, Y. Y., L. Zhang, Y. H. Wu, H. J. Liu, W. W. Mao, J. Du, et al.

    Science.gov (United States)

    2016-01-01

    The above article, published online on 15 October 2015 in Wiley Online Library (http://onlinelibrary.wiley.com/doi/10.1002/ece3.1786/abstract), has been retracted by agreement between the authors, the journal Editor in Chief, Allen Moore, and John Wiley & Sons Ltd. The authors have requested the retraction of their paper because they mistakenly analyzed the wrong backcross lines. This mistake was only recently discovered and they are now in the process of repeating the experiment using the correct Backcross Introgression Lines. The authors apologize for this mistake. Nie, Y. Y., L. Zhang, Y. H. Wu, H. J. Liu, W. W. Mao, J. Du, et al. 2015. Screening of candidate genes and fine mapping of drought tolerance quantitative trait loci on chromosome 4 in rice (Oryza sativa L.) under drought stress. Ecology and Evolution 5(21):5007-5015. doi: 10.1002/ece3.1786. [This retracts the article DOI: 10.1002/ece3.1786.].

  19. Sadhana | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Sadhana. Xudong Chen. Articles written in Sadhana. Volume 36 Issue 3 June 2011 pp 357-369. Influence of free water content on the compressive mechanical behaviour of cement mortar under high strain rate · Jikai Zhou Xudong Chen Longqiang Wu Xiaowei Kan · More Details Abstract Fulltext PDF.

  20. Overexpression of hsa-miR-939 follows by NGFR down-regulation ...

    Indian Academy of Sciences (India)

    2017-02-11

    Feb 11, 2017 ... MicroRNA target prediction; in: Methods in enzymology (eds). JR John, JH Gregory (Academic Press) pp 65–86. Zhang X, Chen C, Wu M, Chen L, Zhang J, Zhang X, et al. 2012. Plasma microRNA profile as a predictor of early virological response to interferon treatment in chronic hepatitis B patients. Antivir.

  1. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. RENFU CHEN. Articles written in Journal of Biosciences. Volume 41 Issue 2 June 2016 pp 229-236 Article. Silencing of HMGA2 promotes apoptosis and inhibits migration and invasion of prostate cancer cells · Zhan Shi Ding Wu Run Tang Xiang Li Renfu Chen Song Xue Chengjing ...

  2. Data release of the LAMOST pilot survey

    National Research Council Canada - National Science Library

    A-Li Luo Hao-Tong Zhang Yong-Heng Zhao Gang Zhao Xiang-Qun Cui Guo-Ping Li Yao-Quan Chu Jian-Rong Shi Gang Wang Jian-Nan Zhang Zhong-Rui Bai Xiao-Yan Chen Feng-Fei Wang Yan-Xin Guo Jian-Jun Chen Bing Du Xiao Kong Ya-Juan Lei Yin-Bi Li Yi-Han Song Yue Wu Yan-Xia Zhang Xin-Lin Zhou Fang Zuo Peng Du Lin He Wen Hou Yi-Qiao Dong Jian Li Guang-Wei Li Shuang Li Jing Song Yuan Tian Meng-Xin Wang Yong-Hui Hou Zhi-Ying Huo Hong-Zhuan Hu Ning-Sheng Hu Zhong-Wen Hu Lei Jia Fang-Hua Jiang Xiang Jiang Zi-Bo Jiang Ge Jin Ai-Hua Li Qi Li Yin-Dun Mao Zheng-Hong Tang Qing-Sheng Tao Liang-Ping Tu Da-Qing Wang Dan Wang Jian-Ping Wang Lei Wang Shou-Guan Wang Shu-Qing Wang Ya-Nan Wang You Wang Yue-Fei Wang Ming-Zhi Wei Xiang-Xiang Xue Xiao-Zheng Xing Ling-Zhe Xu Xin-Qi Xu Yan Xu De-Hua Yang Shi-Hai Yang Zheng-Qiu Yao Yong Yu Hui Yuan Chao Zhai En-Peng Zhang Jing Zhang Li-Ping Zhang WeiZhang Yong Zhang Zhen-Chao Zhang Ming Zhao Fang Zhou Yong-Tian Zhu Jie Zhu Si-Cheng Zou

    2012-01-01

    ...—Nan Zhang ,Zhong—Rui Bai ,Xiao—Yan Chen ,Feng—Fei W ang ,Yan—Xin Guo ,Jian—Jun Chen ,Bing Du1,Xiao KongI,Ya—Juan Lei1,Yin—Bi Li1,Yi—Han Song ,Yue Wu ,Yan—Xia...

  3. Cancer mamma og skjelettmetastaser : Hindrer strålingen videre tumorvekst, og i hvilken grad konsolideres situasjonen i den spongiøse virvelcorpus?

    OpenAIRE

    Kjus, Anne Ragnhild

    2005-01-01

    Cancer mamma and skeletal metastases Abstract written by Anne Ragnhild Kjus, H-00 Background: In human cancers, bone is a predominant site for metastases. It is well known that metastases cause morbidity and mortality in patients with cancer. Breast cancer has a propensity to metastasize to bone. In Norway 2000 women developes breast cancer each year, and the mortality is 750-800 cases. 70% of them suffer from skeletal metastases and the management is palliativ, aimed at providing the...

  4. Adapting Shakespeare from Western Drama to Chinese Opera | Wu ...

    African Journals Online (AJOL)

    Two hundred and forty years after his death, Shakespeare was introduced to China. It was in 1856 that the British missionary William Muirhead mentioned the Bard of Avon in his Chinese translation of British history. In 1878, the first Chinese ambassador in Britain, Guo Song-tao, saw a performance of a Shakespeare play at ...

  5. The Vicissitudes of Walden | Wu | Marang: Journal of Language and ...

    African Journals Online (AJOL)

    Applying the American philosopher Charles Sanders Peirce's semiotics to the reading of Walden Pond, leads to a discovery that the meanings of the pond can never be fixed or static, but will always be vicissitudinous. This insight underscores the point that any analysis of Walden that attempts to adopt a fixed focus is ...

  6. Supply chain management in selected clothing retail businesses / Jianling Wu

    OpenAIRE

    Wu, Jianling

    2004-01-01

    In today's highly competitive, global market place the pressure on organizations to find new ways to create and deliver value to customers grows ever strong. At the same time, market maturity combined with new sources of global competition has led to over-capacity in many industries leading to an inevitable pressure on price. Managers are increasingly interested in actively managing their supply chains because of environmental changes. The study is aimed to identify the importa...

  7. Aluminum for Plasmonics

    Science.gov (United States)

    2014-01-01

    Dielectric functions for the composite metal calculated using this approach (Figure 3c) closely match the ex- perimentallymeasured permittivities ...Slight discrepan- cies appearing in the imaginary permittivity may arise from either metallic granularity, which varies depend- ing on deposition...Enhanced Solar- to- Fuel Energy Conversion. Nano Lett. 2011, 11, 3440– 3446. 8. Chen, H. M.; Chen, C. K.; Chen, C. J.; Cheng, L. C.; Wu, P. C.; Cheng, B. H

  8. Antioxidant activities of seed extracts from Dalbergia odorifera T. Chen

    African Journals Online (AJOL)

    DR. NJ TONUKARI

    2011-09-21

    Sep 21, 2011 ... luxurious furniture and crafts, but also used in the pharmaceutical industry. The dried heartwood or root of the plant is an important traditional Chinese medicine ..... concentrations (Brand et al., 1995). However, the PE and BE did not show a leveling off with increasing concentration. As a result, the radical.

  9. Mitochondrial genome of Taiwan pig ( Sus Scrofa ) | Chen | African ...

    African Journals Online (AJOL)

    The purpose of this study is to investigate the complete nucleotide sequence of the mitochondrial genome of the Taiwan Lanyu pig (Sus scrofa) and its phylogenetic relationships with other pig breeds. Thirty-four forward and reverse primers were designed. Sequencing was performed in both directions. The results showed ...

  10. Food Fortification to Prevent and Control Iron Deficiency | Chen ...

    African Journals Online (AJOL)

    African Journal of Food, Agriculture, Nutrition and Development ... of increasing the level of iron consumption resulting in improved nutritional status. ... followed by a description of ways of protecting and enhancing the absorption of fortification ...

  11. Massive Star Formation: Accreting from Companion X. Chen1 ...

    Indian Academy of Sciences (India)

    system composed of a diffuse object (possible nebulae or UC HII region) and a Massive Young Stellar Object (MYSO) seen in Spitzer IRAC image. The diffuse object and MYSO are connected by the ... Infrared: ISM—stars: formation—ISM: jets and outflows. 1. Introduction. The dynamics processes in Massive Star Formation ...

  12. Food Fortification to Prevent and Control Iron Deficiency | Chen ...

    African Journals Online (AJOL)

    It is essential to prevent the fortification iron from reacting with the absorption inhibitors. To ensure adequate absorption therefore, various factors must be considered before initiating a fortification programme. These include cost effectiveness of fortification in increasing absorbable iron, palatability of the fortified food and the ...

  13. C. Huang , G. Zhao , HW Zhang & YQ Chen

    Indian Academy of Sciences (India)

    to get near to their central stars (Udry et al. 2003). The facts imply that maybe the. [Si/Fe]-high cloud would not be easy to form massive planets. The extrasolar planet systems' discoveries may be influenced by the selection effects. However, most of the. [Si/Fe]-rich planet hosts gather inside 1 AU of semimajor and their ...

  14. Initiation and Propagation of Coronal Mass Ejections P. F. Chen

    Indian Academy of Sciences (India)

    , which is generated at the tachocline layer, emerges throughout the convection zone and the lower atmosphere into the tenuous corona. The coronal field keeps adjusting to a more and more complex magnetic structure in a quasi-steady way.

  15. Dynamics of fractional-ordered Chen system with delay

    Indian Academy of Sciences (India)

    of fractional calculus to various branches of science and engineering have been real- ized only recently. It is becoming more and more clear that derivatives and integrals of non-integer orders are not mere mathematical curiosities but many processes, such as dielectric polarization [1], diffusion [2–5], viscoelastic systems [6] ...

  16. Development of Mouse Models of Ovarian Cancer for Studying Tumor Biology and Testing Novel Molecularly Targeted Therapeutic Strategies

    Science.gov (United States)

    2011-09-01

    Fonseca BD, Sonenberg N. Dissecting the role of mTOR: lessons from mTOR inhibitors. Biochim Biophys Acta 2010;1804:433–9. 22. Chen XG, Liu F, Song XF...FROM THE RESEARCH EFFORT: Kathleen R. Cho (Initiating PI) Yali Zhai (Research Investigator, Cho Laboratory) Rong Wu (Research Assistant Professor...Clin Cancer Res Rong Wu, Tom C. Hu, Alnawaz Rehemtulla, et al. Mouse Model of Ovarian Endometrioid Adenocarcinoma Preclinical Testing of PI3K/AKT

  17. NFAT Signaling and the Tumorigenic Microenvironment of the Prostate

    Science.gov (United States)

    2016-10-01

    visible tumors. Interestingly, all double mutants (PCre/+;RT/+;TN/+;Ptenfl/fl) with both PTEN deficiency and NFATc1 activation developed significantly...Wyczalkowski, Kristine Wylie, Kai Ye, Reyka Jayasinghe, Mingchao Xie, Song Wu, Beifang Niu, Robert Grubb III, Kimberly J. Johnson, Hiram Gay , Ken Chen...Wyczalkowski, Kristine Wylie, Kai Ye, Reyka Jayasinghe, Mingchao Xie, Song Wu, Beifang Niu, Robert Grubb III, Kimberly J. Johnson, Hiram Gay , Ken

  18. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. XIAOQING SUN. Articles written in Journal of Biosciences. Volume 41 Issue 2 June 2016 pp 229-236 Article. Silencing of HMGA2 promotes apoptosis and inhibits migration and invasion of prostate cancer cells · Zhan Shi Ding Wu Run Tang Xiang Li Renfu Chen Song Xue ...

  19. Enhanced high temperature performance of LiMn2O4 coated with ...

    Indian Academy of Sciences (India)

    Author Affiliations. Liu Jinlian1 Wu Xianming1 2 Chen Shang1 2 Liu Jianben1 2 He Zeqiang1 2. College of Chemistry and Chemical Engineering, Jishou University, Jishou 416000, China; Xiangxi Ores and New Materials Development and Service Centre, Jishou 416000, China ...

  20. Thirty-seven transcription factor genes differentially respond to a ...

    Indian Academy of Sciences (India)

    repress SALICYLIC ACID INDUCTION DEFICIENT2 expression to negatively regulate plant innate immunity in. Arabidopsis; Plant Cell 21 2527−2540. Chen L, Qian J, Qu S, Long J, Yin Q, Zhang C, Wu X, Sun F et al. 2008a Identification of specific fragments of HpaGXooc, a harpin from Xanthomonas oryzae pv. oryzicola, ...

  1. Theoretical studies on energetic materials bearing pentaflurosulphyl ...

    Indian Academy of Sciences (India)

    and organometallic compounds (New York: Academic. Press) pp. 218. 26. Zheng Z Q, Wu T H, Mao F L, Zhang Q N and Chen F. 2005 Chem. Eng. Oil Gas 34 87. 27. Balepin A A, Lebedev V P, Miroshnichenko E A,. Koldobskii G I, Ostovskii V A, Larionov B P, Gidaspov. B V and Lebedev Yu A 1977 Svoistva Veshchestv Str.

  2. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Articles written in Journal of Biosciences. Volume 42 Issue 3 September 2017 pp 405-416 Article. Knockdown of Cripto-1 inhibits the proliferation, migration, invasion, and angiogenesis in prostate carcinoma cells · DING WU ZHAN SHI HAO XU RENFU CHEN SONG XUE XIAOQING SUN · More Details Abstract Fulltext PDF.

  3. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Run Tang. Articles written in Journal of Biosciences. Volume 41 Issue 2 June 2016 pp 229-236 Article. Silencing of HMGA2 promotes apoptosis and inhibits migration and invasion of prostate cancer cells · Zhan Shi Ding Wu Run Tang Xiang Li Renfu Chen Song Xue Chengjing Zhang Xiaoqing Sun · More Details Abstract ...

  4. Changming Wang - Journal of Earth System Science | Indian ...

    Indian Academy of Sciences (India)

    Volume 125 Issue 3 April 2016 pp 585-603. Petrogenesis, zircon U–Pb age, and geochemistry of the A-type Mogou syenite, western Henan Province: Implications for Mesozoic tectono-magmatic evolution of the Qinling Orogen · Xinyu He Jionghui Wang Changming Wang Emmanuel John M Carranza Liang Chen Bin Wu.

  5. Antiplasmodial and larvicidal compounds of Toddalia asiatica root ...

    Indian Academy of Sciences (India)

    MS received 30 July 2012; revised 19 March 2013; accepted 4 July 2013. Abstract. From the n-hexane, ethyl ... Toddalia asiatica; Rutaceae; coumarins; alkaloid; antiplasmodial; larvicidal activities. 1. Introduction. The plant Toddalia ..... Chen Y C, Tsai W J, Wu M H, Lin L C and Kuo Y C. 2007 Br. J. Pharmacol. 150 298. 7.

  6. Genetic testing for clinically suspected spinocerebellar ataxias ...

    Indian Academy of Sciences (India)

    Mahesh

    Yichuanxue Zazhi = Chinese Journal of Medical Genetics 27(5): 501–505. Wu, Y. R., H. Y. Lin, C. M. Chen, et al. 2004 Genetic Testing in Spinocerebellar Ataxia in Taiwan: Expansions of Trinucleotide Repeats in SCA8 and SCA17 Are Associated with Typical Parkinson's Disease. Clinical Genetics 65(3): 209–214.

  7. Journal of Chemical Sciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Chemical Sciences. Min Xu. Articles written in Journal of Chemical Sciences. Volume 126 Issue 6 November 2014 pp 1623-1627 Rapid Communications. Synthesis and properties of a dual responsive hydrogel by inverse microemulsion polymerization · Tao Wan Min Xu Liyi Chen Daqing Wu ...

  8. Analysis of embryo, cytoplasmic and maternal genetic correlations ...

    Indian Academy of Sciences (India)

    Author Affiliations. Guo Lin Chen1 2 Jian Guo Wu1 Murali-Tottekkaad Variath1 Zhong Wei Yang1 Chun Hai Shi1. Department of Agronomy, Zhejiang University, Hangzhou, 310029, People's Republic of China; School of Agriculture and Food Science, Zhejiang A & F University, Linan, 311300, People's Republic of China ...

  9. African Health Sciences - Vol 16, No 3 (2016)

    African Journals Online (AJOL)

    Chien-Wei Liao, Chung-Jung Fu, Cheng-Yan Kao, Yueh-Lun Lee, Po-Ching Chen, Ting-Wu Chuang, Toshio Naito, Chia-Mei Chou, Ying-Chie Huang, Idalina Bonfim, Chia-Kwung Fan, 690-697 .... Analysis of personality traits as a risk factor in crash related trauma · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT

  10. exchange femoral nailings at kenyatta national hospital abstract ...

    African Journals Online (AJOL)

    Shroeder, J. E. Mosheiff,R. And Khoury, A. The outcome of closed, intramedullary exchange nailing with reamed insertion in the treatment of femoral shaft nonunions. J.Orthopaedic Trauma. 2009: 9;653-657. 6. Yu,C.W.,Wu,C.C. and Chen,W .J. Aseptic nonunion of a femoral shaft treated using exchange nailing. Chang.

  11. Preparation and investigation of optical, structural, and ...

    Indian Academy of Sciences (India)

    Adame,. Superlatt. Microstruct. 42, 94 (2007). [43] U Ilyas, R S Rawat, T L Tan, P Lee, R Chen, H D Sun, L Fengji and S Zhang, J. Appl. Phys. 111, 033503 (2012). [44] X L Wu, G G Siu, C L Fu and H C Ong, Appl. Phys. Lett. 78, 2285 (2001).

  12. Sequential Delivery of BMP-2 and IGF-1 Using a Chitosan Gel with gelatin Microspheres Enhances Early osteoblastic Differentiation

    Science.gov (United States)

    2012-01-18

    derived growth factor from reactive two-component polyurethane scaffolds on the healing in rat skin excisional wounds. Biomaterials 2009;30(20):3486...49. [23] Chen FM, Zhao YM, Wu H, Deng ZH, Wang QT, Jin Y. Enhancement of periodontal tissue regeneration by locally controlled delivery of insulin

  13. Theoretical Criteria for Scattering Dark States in Nanostructured Particles

    Science.gov (United States)

    2014-01-01

    Neumann, O.; Mirin , N. A.; Nordlander, P.; Halas, N. J. Nano Lett. 2008, 8, 3481–3487. (27) Wu, X.; Gray, S. K.; Pelton, M. Opt. Express 2010, 18...Mukherjee, S.; Mirin , N. A.; Levit, S. D.; Nordlander, P.; Halas, N. J. J. Phys. Chem. C 2010, 114, 7378–7383. 16 (60) Wang, M.; Cao, M.; Chen, X.; Gu

  14. Journal of Genetics | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Genetic diversity of bitter taste receptor gene family in Sichuan domestic and Tibetan chicken populations · YUAN SU DIYAN LI UMA GAUR YAN WANG NAN WU BINLONG CHEN HONGXIAN XU HUADONG YIN YAODONG HU QING ZHU · More Details Abstract Fulltext PDF. The sense of bitter taste plays a critical role in ...

  15. African Journal of Neurological Sciences 2010 - Vol. 29, No 2 http ...

    African Journals Online (AJOL)

    KESKIL S, BAYKANER K, CEVIKER N, IªIK S, CENGEL M, ORBAY T. Clinical significance of acute traumatic intracranial pneumocephalus. Neurosurg Rev. 1998;21(1):10-3. 6. LEE CH, CHEN WC, WU CI, HSIA TC. Tension pneumocephalus: a rare complication after hyperbaric oxygen therapy. Am J Emerg Med. 2009 Feb ...

  16. Mesenteric ischemia, high altitude and Hill's criteria

    African Journals Online (AJOL)

    evaluation and therapy. Acta Gastroenterol Belg. 2002;65:220-5. 21. Tsai CJ, Kuo YC, Chen PC, Wu CS. ... Superior mesenteric vein thrombosis with radiologically occult cause: A retrospective study of 43 cases. AJR Am ... tertiary centers where such modalities exist. Thus, it is not surprising that data from these parts of the.

  17. Tandem base-free synthesis of -hydroxy sulphides under ...

    Indian Academy of Sciences (India)

    Author Affiliations. Guang-Shu Lv1 Fu-Junduan1 Jin-Chang Ding1 2 Tian-Xing Cheng1 Wen-Xia Gao1 Jiu-Xi Chen1 Hua-Yue Wu1. College of Chemistry and Materials Engineering, Wenzhou University, Wenzhou 325035, P. R. China; Wenzhou Vocational and Technical College, Wenzhou, 325035, P. R. China ...

  18. Stimulation of taxane production in suspension cultures of Taxus ...

    African Journals Online (AJOL)

    STORAGESEVER

    2008-06-17

    Jun 17, 2008 ... biosynthesis in transformed root cultures of Datura stramonium. Phytochemistry 50: 53-56. Zhang CH, Fevereiro PS, He G, Chen Z (2007). Enhanced paclitaxel productivity and release capacity of Taxus chinensis cell suspension cultures adapted to chitosan. Plant Sci. 172: 158-163. Zhang CH, Wu JY, He ...

  19. Zhan Shi

    Indian Academy of Sciences (India)

    ZHAN SHI. Articles written in Journal of Biosciences. Volume 41 Issue 2 June 2016 pp 229-236 Article. Silencing of HMGA2 promotes apoptosis and inhibits migration and invasion of prostate cancer cells · Zhan Shi Ding Wu Run Tang Xiang Li Renfu Chen Song Xue Chengjing Zhang Xiaoqing Sun · More Details Abstract ...

  20. High Serum 25-hydroxyvitamin D is Associated with Low Incidence of Stress Fractures

    Science.gov (United States)

    2011-06-01

    of Family and Preventive Medicine, School of Medicine, University of California, San Diego, La Jolla, California 3 Osteoporosis Research Center...surveillance. Am J Public Health. 2002 Dec;92(12):1900-4. 19. Beck TJ, Petit MA, Wu G, LeBoff MS, Cauley JA, Chen Z. Does obesity really make the

  1. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences. SONG XUE. Articles written in Journal of Biosciences. Volume 41 Issue 2 June 2016 pp 229-236 Article. Silencing of HMGA2 promotes apoptosis and inhibits migration and invasion of prostate cancer cells · Zhan Shi Ding Wu Run Tang Xiang Li Renfu Chen Song Xue Chengjing ...

  2. Timing of gene expression from different genetic systems in shaping ...

    Indian Academy of Sciences (India)

    Author Affiliations. Guo Lin Chen1 2 Jian Guo Wu1 Murali-Tottekkaad Variath1 Chun Hai Shi1. Department of Agronomy, Zhejiang University, Hangzhou, 310029, People's Republic of China; School of Agriculture and Food Science, Zhejiang A & F University, Lin'an, 311300, People's Republic of China ...

  3. Role of microRNA-195 in cardiomyocyte apoptosis induced by ...

    Indian Academy of Sciences (India)

    VAV2, and CDC42. Hepatology 58, 642–653. Wu S. H., Hang L. W., Yang J. S., Chen H. Y., Lin H. Y., Chiang. J. H. et al. 2010 Curcumin induces apoptosis in human non-small cell lung cancer NCI-H460 cells through ER stress and caspase cascade- and mitochondria-dependent pathways. Anticancer Res. 30, 2125–2133.

  4. Journal of Earth System Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Response of geomorphic and geological processes to insufficient and ample sediment supply along the upper continental slope in the north-western South China Sea · Hongjun Chen Wenhuan Zhan Shiguo Wu · More Details Abstract Fulltext PDF. We document upper slope sedimentary process and strata on the passive ...

  5. Connections between the Radio, Optical and Soft X-ray Luminosities ...

    Indian Academy of Sciences (India)

    (SSRQs, α > 0.5). The common features of FSRQs are usually associated with jets and are characterized by the high polarization, violent flux variability, high luminos- ity, apparent superluminal motion and beaming effect (Urry & Padovani 1995; Wu et al. 2004; Chen et al. 2011). However, formation of jets remains unknown, ...

  6. Prompt Global Strike: China and the Spear

    Science.gov (United States)

    2014-04-01

    Aeronautica et Astronautica Sinica), Issue 5, September 2008, pp. 1091-1097. 83 Cai Lin, Wu Qian, and Lei Li are affiliated with the Southwest China...Hangkong xuebao (Acta Aeronautica et Astronautica Sinica), Issue 5, September 2008; Chen Xiaoqing, Hou Zhongxi, and Liu Jianxia, “Gao chaoshengsu

  7. The Promotion of a Functional Fibrosis in Skeletal Muscle with Volumetric Muscle Loss Injury Following the Transplantation of Muscle-ECM

    Science.gov (United States)

    2013-02-04

    using a Thomas Wiley Mini-Mill (Thomas Scientific) and passed through a number 20 mesh (w841 mm). 2.3. Bone marrow-derived mesenchymal stem cell...C Methods. http://dx.doi.org/10.1089/ten.TEC.2012.0290. Available from: http://www.ncbi.nlm.nih.gov/ pubmed /22992043; 2012. [14] Wu X, Corona BT, Chen

  8. N(HI) and Jet Power/Emission in AGNs Zhongzu Wu1,∗ , Minfeng ...

    Indian Academy of Sciences (India)

    Abstract. Neutral hydrogen (HI) 21-cm absorption has been detected against very powerful radio jets. In this paper, based on Gupta's sample. (Gupta et al. 2006), we present our preliminary study of the correlations between the HI column density N(HI) and the jet power, N(HI) versus the low frequency luminosity at 408 MHz, ...

  9. Reviving ancient Chinese mathematics mathematics, history and politics in the work of Wu Wen-Tsun

    CERN Document Server

    Hudecek, Jiri

    2014-01-01

    Twentieth-century China has been caught between a desire to increase its wealth and power in line with other advanced nations, which, by implication, means copying their institutions, practices and values, whilst simultaneously seeking to preserve China's independence and historically formed identity. Over time, Chinese philosophers, writers, artists and politicians have all sought to reconcile these goals and this book shows how this search for a Chinese way penetrated even the most central, least contested area of modernity: science.Reviving Ancient Chinese Mathematics is a study of the life

  10. Restoration and source identification of polycyclic aromatic hydrocarbons after the Wu Yi San oil spill, Korea.

    Science.gov (United States)

    Jang, Yu Lee; Lee, Hyo Jin; Jeong, He Jin; Park, Shin Yeong; Yang, Won Ho; Kim, Heung-Yun; Kim, Gi Beum

    2016-10-15

    On January 31, 2014, an oil spill accident occurred in Yeosu, South Korea. A total 800-899kl of oil from the pipeline was spilled into the sea. After the oil spill, the KIOST (Korea Institute of Ocean Science & Technology) researched PAHs (polycyclic aromatic hydrocarbons) in various media, but sedimentary PAHs were not analyzed despite their longer persistency than in other media. Therefore, this study examined PAH levels in intertidal sediments around Gwangyang Bay and identified PAH sources using oil fingerprinting. PAH residual levels showed a dramatic decrease during the four months after the accident and then remained at a relatively constant level. Analysis through regression equations indicate that this study area is likely to be restored to the PAH levels prior to the accident. Furthermore, the source analysis and oil fingerprinting analysis showed that PAH contamination in this study was unlikely to have originated from the spilled oil. Copyright © 2016. Published by Elsevier Ltd.

  11. BN~r" .wU1!9 1\\ I

    Indian Academy of Sciences (India)

    email, postal and residential address, telephone numbers, academic qualifications starting from B.Sc 'onwards, teaching experience, courses taught, positions held and a statement indicating reasons for interest in participating in the course. Teachers applying for participation are also requested to indicate that necessary ...

  12. You Wei and Wu Wei: Ambivalence of Chinese outbound mergers and acquisitions

    NARCIS (Netherlands)

    Sun, Z.

    2016-01-01

    China is assuming an increasingly prominent position in the world economy as the investment begins to flow from China to the world. Compared to the ‘West goes to China’, the institutional environment, the cultural roots and the corresponding managerial behaviours are quite distinct. These distinct

  13. Analysing the Wu metric on a class of eggs in Cn–II

    Indian Academy of Sciences (India)

    Author Affiliations. G P BALAKUMAR1 PRACHI MAHAJAN2. Indian Statistical Institute, Chennai 600 113, India; Department of Mathematics, Indian Institute of Technology – Bombay, Mumbai 400 076, India ...

  14. Effect of Zhen-wu decoction on chronic heart failure in rats

    African Journals Online (AJOL)

    legislation_en.htm. 16. Seddon M, Looi YH, Shah AM. Oxidative stress and redox signalling in cardiac hypertrophy and heart failure. Heart 2006; 12: 131-138. 17. Azevedo PS, Minicucci MF, Santos PP. Energy metabolism in cardiac remodeling and ...

  15. Estimating Black Hole Masses of Blazars Xue-Bing Wu1,∗ , FK Liu1 ...

    Indian Academy of Sciences (India)

    Using this technique, the BLR size can be measured using the time lag between variations of continuum and emission line fluxes. The black hole mass can be derived from the BLR size and the characteristic velocity using the virial law. So far, reverberation mapping studies have yielded black hole masses of about 40.

  16. Molecular epidemiology of WU polyomavirus in hospitalized children with acute respiratory tract infection in China.

    Science.gov (United States)

    Zhu, Teng; Lu, Qing-Bin; Zhang, Shu-Yan; Wo, Ying; Zhuang, Lu; Zhang, Pan-He; Zhang, Xiao-Ai; Wei, Wei; Liu, Wei

    2017-05-01

    To explore the molecular epidemiology and clinical characteristics of Washington University polyomavirus (WUPyV) infection in pediatric patients with acute respiratory tract infections in China. A laboratory surveillance was performed to recruit pediatric patients with acute respiratory tract infections. WUPyV was detected using real-time PCR and complete genome was sequenced for randomly selected positive nasopharyngeal aspirate. Altogether 122 (7.5%) of 1617 children found to be infected with WUPyV and 88 (72.1%) were coinfected with other viruses during 2012-2015. The phylogenetic analysis showed that 14 strains from our study formed two new clusters (Id and IIIc) within the Branch I and Branch III, respectively. WUPyV is persistently circulating in China. Surveillance on WUPyV infection in wider areas and long persistence is warranted.

  17. Effect of healthy Qigong “WuQinXi” exercise on peripheral blood T ...

    African Journals Online (AJOL)

    USER

    2010-07-19

    Jul 19, 2010 ... tation in order to enhance their TCC skills and provide an exercise cool-down. All participants were asked to continue their normal living routines without restricting their diets or altering their eating habits. After 3 months (when subjects had fasted for at least 8 h), blood was collected, centrifuged at 3500 rpm ...

  18. Analysing the Wu metric on a class of eggs in ℂn – I

    Indian Academy of Sciences (India)

    G P BALAKUMAR

    imal metric η, form a new metric whose unit ball about the origin in each tangent space, is the ellipsoid of minimal volume containing the unit ball with respect to η. By an ellip- soid, we mean the image of a ball in the standard l2-norm, under a linear automorphism of. Cn. As ellipsoids furnish the simplest compact convex sets ...

  19. Effect of Zhen-wu decoction on chronic heart failure in rats | Liu ...

    African Journals Online (AJOL)

    Tropical Journal of Pharmaceutical Research. Journal Home · ABOUT THIS JOURNAL · Advanced Search · Current Issue · Archives · Journal Home > Vol 16, No 10 (2017) >. Log in or Register to get access to full text downloads.

  20. Chemically Tunable 2D Materials

    Science.gov (United States)

    2016-06-30

    2015, 44, 5861- 5896. 18 J. Zhao, Z. Wang, J. C. White and B. Xing , Environ. Sci. Techno/., 2014, 48, 9995-10009. 19 V. C. Sanchez, A. jachak, R. H...143. 117 T. Tong, A. Shereef, J. Wu , C. T. T. Binh, J. J. Kelly, J.-F. Gaillard and K. A. Gray, Environ. Sci. Technol., 2013, 47, 12486- 12495. 118...S. Liu, M. Hu, T. H. Zeng, R. Wu , R. Jiang,]. Wei, L. Wang, J. Kong andY. Chen, Langmuir, 2012, 28, 12364- 12372. 119 ]. Fan, Y. Li, H. N. Nguyen, Y

  1. Commentary on "Integrative clinical genomics of advanced prostate cancer". Robinson D, Van Allen EM, Wu YM, Schultz N, Lonigro RJ, Mosquera JM, Montgomery B, Taplin ME, Pritchard CC, Attard G, Beltran H, Abida W, Bradley RK, Vinson J, Cao X, Vats P, Kunju LP, Hussain M, Feng FY, Tomlins SA, Cooney KA, Smith DC, Brennan C, Siddiqui J, Mehra R, Chen Y, Rathkopf DE, Morris MJ, Solomon SB, Durack JC, Reuter VE, Gopalan A, Gao J, Loda M, Lis RT, Bowden M, Balk SP, Gaviola G, Sougnez C, Gupta M, Yu EY, Mostaghel EA, Cheng HH, Mulcahy H, True LD, Plymate SR, Dvinge H, Ferraldeschi R, Flohr P, Miranda S, Zafeiriou Z, Tunariu N, Mateo J, Perez-Lopez R, Demichelis F, Robinson BD, Schiffman M, Nanus DM, Tagawa ST, Sigaras A, Eng KW, Elemento O, Sboner A, Heath EI, Scher HI, Pienta KJ, Kantoff P, de Bono JS, Rubin MA, Nelson PS, Garraway LA, Sawyers CL, Chinnaiyan AM.Cell. 21 May 2015;161(5):1215-1228.

    Science.gov (United States)

    Freedland, Stephen J; Aronson, William J

    2017-08-01

    Toward development of a precision medicine framework for metastatic, castration-resistant prostate cancer (mCRPC), we established a multi-institutional clinical sequencing infrastructure to conduct prospective whole-exome and transcriptome sequencing of bone or soft tissue tumor biopsies from a cohort of 150 mCRPC affected individuals. Aberrations of AR, ETS genes, TP53, and PTEN were frequent (40%-60% of cases), with TP53 and AR alterations enriched in mCRPC compared to primary prostate cancer. We identified new genomic alterations in PIK3CA/B, R-spondin, BRAF/RAF1, APC, β-catenin, and ZBTB16/PLZF. Moreover, aberrations of BRCA2, BRCA1, and ATM were observed at substantially higher frequencies (19.3% overall) compared to those in primary prostate cancers. A total of 89% of affected individuals harbored a clinically actionable aberration, including 62.7% with aberrations in AR, 65% in other cancer-related genes, and 8% with actionable pathogenic germline alterations. This cohort study provides clinically actionable information that could affect treatment decisions for these affected individuals. Copyright © 2017 Elsevier Inc. All rights reserved.

  2. An effective and secure key-management scheme for hierarchical access control in E-medicine system.

    Science.gov (United States)

    Odelu, Vanga; Das, Ashok Kumar; Goswami, Adrijit

    2013-04-01

    Recently several hierarchical access control schemes are proposed in the literature to provide security of e-medicine systems. However, most of them are either insecure against 'man-in-the-middle attack' or they require high storage and computational overheads. Wu and Chen proposed a key management method to solve dynamic access control problems in a user hierarchy based on hybrid cryptosystem. Though their scheme improves computational efficiency over Nikooghadam et al.'s approach, it suffers from large storage space for public parameters in public domain and computational inefficiency due to costly elliptic curve point multiplication. Recently, Nikooghadam and Zakerolhosseini showed that Wu-Chen's scheme is vulnerable to man-in-the-middle attack. In order to remedy this security weakness in Wu-Chen's scheme, they proposed a secure scheme which is again based on ECC (elliptic curve cryptography) and efficient one-way hash function. However, their scheme incurs huge computational cost for providing verification of public information in the public domain as their scheme uses ECC digital signature which is costly when compared to symmetric-key cryptosystem. In this paper, we propose an effective access control scheme in user hierarchy which is only based on symmetric-key cryptosystem and efficient one-way hash function. We show that our scheme reduces significantly the storage space for both public and private domains, and computational complexity when compared to Wu-Chen's scheme, Nikooghadam-Zakerolhosseini's scheme, and other related schemes. Through the informal and formal security analysis, we further show that our scheme is secure against different attacks and also man-in-the-middle attack. Moreover, dynamic access control problems in our scheme are also solved efficiently compared to other related schemes, making our scheme is much suitable for practical applications of e-medicine systems.

  3. The enhanced interface effect induced by thermal pressure in Nd0 ...

    Indian Academy of Sciences (India)

    [2] Yang C P, Chen S S, Zhou Z H, Xu L F, Wang H, Hu J F,. Morchshakov V and Bärner K 2007 J. Appl. Phys. 101 063909. [3] Yu C Y, Feng P and Fei Z 2010 N. J. Phys. 12 023008. [4] Quintero M, Levy P, Leyva A G and Rozenberg M J 2007. Phys. Rev. Lett. 98 116601. [5] Liu S Q, Wu N J and Ignatiev A 2000 Appl. Phys.

  4. An efficient one-pot synthesis of novel pyrazolophthalazinyl ...

    Indian Academy of Sciences (India)

    Administrator

    thesis 19 3238; (d) Wang Y, Shang Z-C, Wu T-X,. Fan J-C and Chen X 2006 J. Mol. Catal. A: Chem. 253 212; (e) Shen Z, Li B, Wang L and Zhang Y. 2005 Tetrahedron Lett. 46 8785. 12. (a) Shanthi G, Subbulakshmi G and Perumal P T. 2007 Tetrahedron 63 2057; (b) Shanthi G and Peru- mal P T 2007 Tetrahedron Lett.

  5. Characterization of an E3 Ubiquitin Ligase that Degrades Neurofibromin in Vitro and Vivo

    Science.gov (United States)

    2012-04-01

    glioblastoma multi- forme, malignant peripheral nerve sheath tumor and epithelial cancers in the ovary and lung (Ding et al., 2008; Parsons et al., 2008; Sangha... sheath in type 1 neurofibromatosis. Am. J. Med. Genet. 89, 23–30. Wu, K., Fuchs, S.Y., Chen, A., Tan, P., Gomez, C., Ronai, Z., and Pan, Z.Q. (2000). The... myelin of axons and astrocytes that provide trophic and functional support for neurons (Rowitch and Kriegstein, 2010). The clinical observations that only

  6. Browse Title Index

    African Journals Online (AJOL)

    C Amirinia, HR Seyedabadi, N Amirmozafari, RV Torshizi, M Chamani, AJ Aliabad, MA Abbasi. Vol 12, No 2 ... Xue-Xia Wu, Hai-Dong Ding, Jian-Lin Chen, Hong-Juan Zhang, Wei-Min Zhu. Vol 10, No 50 ... MI Sánchez-López, SF Vanhulle, V Mertens, G Guerra, SH Figueroa, C Decock, A Corbisier, MJ Penninckx. Vol 7, No 5 ...

  7. Berlinale tõstab kilbile "Teekonna Guatanamosse" / Grete Nootre

    Index Scriptorium Estoniae

    Nootre, Grete

    2006-01-01

    56. Berliini filmifestivali programmidest ja filmidest - Suurbritannia poliitiline mängufilm "Teekond Guatanamosse" ("The Road to Guatanamo") : režissöörid Michael Winterbottom, Mat Whitecross, Hiina mängufilm "Lubadus" ("Wu ji") : režissöör Chen Kaige, Suurbritannia - Saksamaa "V nagu vendette" ("V for Vendette") : režissöör James McTeigue

  8. Comparison of single agent versus combined chemotherapy in previously treated patients with advanced urothelial carcinoma: a meta-analysis

    OpenAIRE

    Wu XJ; Zhi Y; He P; Zhou XZ; Zheng J.; Chen ZW; Zhou ZS

    2016-01-01

    Xiao-Jun Wu, Yi Zhi, Peng He, Xiao-Zhou Zhou, Ji Zheng, Zhi-Wen Chen, Zhan-Song Zhou Institute of Urinary Surgery, Southwest Hospital, Third Military Medical University, Chongqing, People’s Republic of China Background: Platinum-based chemotherapy is the standard treatment for advanced urothelial cancer (UC) and is generally used in the first-line setting. However, the optimal salvage treatment for previously treated UC patients is unclear. We conducted a systematic review of publ...

  9. Annealing twins in a multifunctional beta Ti–Nb–Ta–Zr–O alloy

    Indian Academy of Sciences (India)

    Administrator

    Cahn R W and Haasen P 1996 Physical metallurgy (Amsterdam: North Holland) 4th edn. Furuta T, Kuramoto S, Hwang J, Nishino K and Saito T 2005. Mater. Trans., JIM 46 3001. Guo W Y, Xing H, Sun J, Li X L, Wu J S and Chen R 2008. Metall. Mater. Trans. A39 672. Gutkin M Y, Ishizaki T, Kuramoto S and Ovid'ko I A 2006.

  10. Reasons for not having received influenza vaccination and its predictors in Canadians

    OpenAIRE

    Chen, Yue; Yi,; Wu,; Laroche,; Wong,

    2012-01-01

    Yue Chen,1 Jun Wu,2 Qi-long Yi,1 Julie Laroche,3 Thomas Wong21Department of Epidemiology and Community Medicine, Faculty of Medicine, University of Ottawa, 2Professional Guidelines and Public Health Practice Division, Centre for Communicable Diseases and Infection Control, Public Health Agency of Canada, 3Immunization Assessment and Information, Centre for Immunization and Respiratory Infectious Diseases, Public Health Agency of Canada, Ottawa, Ontario, CanadaBackground: Influenza vaccination...

  11. Electron paramagnetic resonance parameters of Mn4+ ion in h ...

    Indian Academy of Sciences (India)

    569–575. Electron paramagnetic resonance parameters of Mn4+ ion in h-BaTiO3 crystal from a two-mechanism model. WU XIAO-XUAN1,4,∗, FANG WANG2, FENG WEN-LIN2,3 and. ZHENG WEN-CHEN2,4. 1Department of Physics, Civil Aviation Flight University of China, Guanghan 618307,. People's Republic of China.

  12. Genome-Wide Chromosomal Targets of Oncogenic Transcription Factors

    Science.gov (United States)

    2008-04-01

    Method. Methods 25: 402–408. Loh, Y.H., Wu, Q., Chew, J.L., Vega, V.B., Zhang, W., Chen, X., Bourque, G., George , J., Leong, B., Liu, J., et al. 2006...shock. Genes Dev 20: 2250–2265. 32. Guillemette B, Bataille AR, Gevry N, Adam M, Blanchette M, et al. (2005) Variant histone H2A.Z is globally localized

  13. Fully Passive Microelectromechanical Near Zero Power Wake Up Receiver for Ultra Low Power Applications

    Science.gov (United States)

    2017-03-01

    Fully Passive Microelectromechanical Near Zero Power Wake Up Receiver for Ultra Low Power Applications Cristian Cassella, Tao Wu, Guofeng Chen...William Zhu, Gwendolyn Hummel, Nicol McGruer and Matteo Rinaldi Northeastern University, Boston, USA INTRODUCTION Low- power wireless sensing...transmitted when requested by other interrogating nodes in the network. One of the main sources of energy loss in conventional WSNs is the power

  14. Chen et al., Afr J Tradit Complement Altern Med. (2014) 11(1):15-22

    African Journals Online (AJOL)

    cadewumi

    x300mm,Japan ) column. The columns were eluted with 0.1M nitric acid and calibrated with ..... Mushiake, H, Tsunoda, T, Nukatsuka,M, Shimao K, Fukushima M, Tahara H. (2005). Dendritic cells might be one of key factors for eliciting antitumor ...

  15. Chen et al., Afr J Tradit Complement Altern Med. (2014) 11(1):15-22

    African Journals Online (AJOL)

    cadewumi

    1Medical School of Taizhou University, Taizhou, Zhejiang 318000, China, 2College of .... 3 ml of ice-cold staining buffer was then added with the incubation for 5 min at 4℃ followed by 200 ..... Timeline: Chemotherapy and the war on cancer.

  16. Modellierung von Oberflächen mit Diskontinuitäten

    Science.gov (United States)

    Borkowski, Andrzej

    The laser scanning provides very dense information about the surface to be modelled in the form of a irregularly distributed points cloud {x, y, z} from R3. Such dense information makes possible an efficient modelling of characteristic structures of the terrain surface like discontinuities, which are necessary for high-qualitative description of the surface. Simultaneously, the points not belonging to the modelled surface (for example: reflexes from buildings, trees etc.) stand a very important influence on the obtained data. During the modelling process, such data should be effectively filtered from the whole data set. The laser scanning data can be efficiently elaborated by the use of deformable models of curves and surfaces. These models base on the physical principle of energy-minimizing and are presented as the solution of variational problem. The total energy consists both of internal and external energy. The external energy, depending on a context is generated by the data; in most cases it describes a deviation between the data and a model. The algorithms and approaches developed in this work have been tested on real data sets obtained by a laser scanning. Furthermore, a qualitative consideration of a modelling has been given. Finally, some hints for user according the steering and operating of the approaches have been presented.

  17. Reaktionen gesättigter Kohlenwasserstoffe in der Gasphase und an Oberflächen

    OpenAIRE

    Ryll, Thomas

    2015-01-01

    In der vorliegenden Arbeit konnte erstmals gezeigt werden, dass die Konvertierung von Methan zu Acetylen mit Ausbeuten von über 99 % und Selektivitäten größer als 200:1 mit dem Einsatz von „continious wave“ (cw) Mikrowellenplasmen großtechnisch möglich ist. Im Gegensatz zu vorangegangenen Arbeiten[1,3,5,6] konnte der Vorteil von cw Mikrowellenplasmen in Bezug auf Ausbeute und Selektivität herausgestellt werden. Die vielfach beschriebenen Probleme der Rußbildung[7,8] konnten mit dem Einsatz d...

  18. In search of low cost titanium: the fray farthing chen (FFC) cambridge process

    CSIR Research Space (South Africa)

    Oosthuizen, SJ

    2011-03-01

    Full Text Available . Topics explored include the history of the process, attempts at commercial- ization, NASA?s alternative application, and present status of the process. Keywords FFC Cambridge, titanium, molten salt. * Materials Science and Manufacturing, CSIR.... Oxygen production for rocket propulsion promises by far the greatest cost and mass saving of any off-world in situ resource utilization (ISRU). Since the 1960s most work on lunar resource utilization focused on the mineral ilmenite (FeTiO3...

  19. Untersuchung der Nährstoffauswaschung unter Schotterrasenflächen an einem inneralpinen Standort

    Science.gov (United States)

    Slawitsch, Veronika; Birk, Steffen; Pötsch, Erich M.

    2016-09-01

    Surface stabilisation by planted gravel turf is a reliable alternative to conventionally-paved parking lots. At the HBLFA Raumberg-Gumpenstein test site, biennial nutrient concentrations in seepage water and nutrient leachate fluxes were analysed using six gravity lysimeters. Two different materials (limestone with 10 % humus and recycled building material with 10 % compost) were investigated. Seepage water fluxes showed better infiltration for lime gravel materials in comparison to recycled building materials. The nutrient concentrations and leachate flux showed significantly higher values in the recycled building materials in both years of the experiment. Both materials showed a decrease in nutrient concentration and leaching from the first to the second year. The nitrate threshold concentration given by the drinking water directive (Trinkwasserverordnung BGBI. I Nr. 21/2001) was met for lime materials but was exceeded by a factor of three for recycled building materials within the first year. In terms of groundwater protection, the high risk of nitrate leaching in the first year has to be considered if using recycled building material.

  20. On the automatic link between affect and tendencies to approach and avoid : Chen and Bargh revisited

    NARCIS (Netherlands)

    Rotteveel, M.; Gierholz, A.; Koch, G.; van Aalst, C.; Pinto, Y.; Matzke, D.; Steingroever, H.; Verhagen, J.; Beek, T.F.; Selker, R.; Sasiadek, A.; Wagenmakers, E.-J.

    2015-01-01

    Within the literature on emotion and behavioral action, studies on approach-avoidance take up a prominent place. Several experimental paradigms feature successful conceptual replications but many original studies have not yet been replicated directly. We present such a direct replication attempt of

  1. Über Schwächen und Stärken des Völkerrechts

    OpenAIRE

    Kunig, Philip

    2015-01-01

    Zu beiden Fragen für das deutsche Rechtssystem Philip Kunig, Verfassungsrecht und einfaches Recht ― Verfassungsgerichtsbarkeit und Fachgerichtsbarkeit, in: Veröffentlichungen der Vereinigung der Deutschen Staatsrechtslehrer 61 (2001), 34

  2. In search of low cost titanium: the Fray Farthing Chen (FFC) Cambridge process

    CSIR Research Space (South Africa)

    Oosthuizen, SJ

    2010-10-01

    Full Text Available of aggressive/reactive chemicals to deliver “titanium sponge”, which requires capital and labor intensive product recovery, handling and processing. The batches of titanium sponge are produced over several days in steel vessels, delivering around 10 tons... in technology transfer, innovation management and investment rounds from seed to IPO. 2002 – 2003 COMMERCIAL DIRECTOR, HEAD PORTER, CAMBRIDGE, UK • Head Porter is a wireless technology start-up company founded by four students at the University...

  3. Polychlorinated biphenyl (PCB) congeners in Mussel and other mollusc from Da Chen Island, East China Sea

    Energy Technology Data Exchange (ETDEWEB)

    Chu, S.G.; Xi, Z.Q.; Xu, X.B [Research Center for Eco-Environmental Sciences, Academia Sinica, Beijing (China)

    1995-11-01

    Polychlorinated biphenyls (PCBs) are among the most persistent and toxic pollutants in environment. Determination of these contaminants in fish, shellfish and other mollusc is very important, not only because these aquatics are important food for mankind, but also because they can bioconcentrate contaminants preferentially in their adipose tissue, and serve as biomarker of the aquatic pollution. Mussels and oysters have been widely used to monitor the pollution in the coastal environment. The aim of the study was to investigate the concentrations and the main source of PCBs in mussels and other mollusca from the coastal areas of East China Sea. 10 refs., 3 figs., 2 tabs.

  4. Pemberian Suaka Diplomatik Kepada Tahanan Rumah Chen Guang Cheng Oleh Kedutaan Besar Amerika Serikat Di Beijing

    OpenAIRE

    Wulandari, Ayu Indah

    2017-01-01

    Asylum is the grant of protection granted by a State to an individual or more who requests it and the reason why the individual or individuals are protected is based on humanitarian, religious, racial, political, and so forth (refugee grounds; Ride on life) and Intervention is a form of state intervention on the affairs or sovereignty of another State. The purpose of this study is to Know and understand the suitability between the grant of Diplomatic Asylum conducted by the United States E...

  5. Verfahren zur Identifizierung von oberflächen-adhäsiven Peptidsequenzen

    OpenAIRE

    Grunwald, Ingo; Colombi Ciacchi, Lucio; Steckbeck, Sascha

    2014-01-01

    Characterizing surface adhesive properties of a peptide or protein by: providing a sample mixture containing two or more peptide fragments of a peptide or protein; determining the masses of the peptide fragments by a mass spectrometry and creating a reference peptide mass fingerprint; applying the sample mixture in an inorganic or organic substrate surface with respect to the surface adhesive properties; determining the masses of the peptide fragments not bound to the substrate surface and cr...

  6. VizieR Online Data Catalog: Sample of Fermi Blazars (Chen+, 2016)

    Science.gov (United States)

    Chen, Y.-Y.; Zhang, X.; Xiong, D.-R.; Wang, S.-J.; Yu, X.-L.

    2016-04-01

    We tried to select a large number of blazars with reliable redshift, radio core and extended radio luminosity at 1.4GHz. Firstly, we considered the following samples of blazars to get the radio core luminosity and extended luminosity at 1.4GHz: Kharb et al. (2010, J/ApJ/710/764), Antonucci & Ulvestad (1985ApJ...294..158A), Cassaro et al. (1999A&AS..139..601C), Murphy et al. (1993MNRAS.264..298M), Landt & Bignall (2008MNRAS.391..967L), Caccianiga & Marcha (2004, Cat. J/MNRAS/348/973), Giroletti et al. (2004). We cross-correlated these samples with the Fermi LAT Third Source Catalog (3FGL), and we acquired the 3FGL spectral index and energy flux at 0.1-100GeV from clean sources in 3FGL (Fermi-LAT Collaboration 2015, J/ApJS/218/23) Using these catalogs, we compiled 201 Fermi blazars. (1 data file).

  7. Chen's double sieve, Goldbach's conjecture and the twin prime problem, 2

    Science.gov (United States)

    Wu, J.

    For every even integer N, denote by D_{1,2}(N) the number of representations of N as a sum of a prime and an integer having at most two prime factors. In this paper, we give a new lower bound for D_{1,2}(N).

  8. AtCCX1 transports Na + and K + in Pitch pastoris | Chen | African ...

    African Journals Online (AJOL)

    Yeast expressing AtCCX1 grew better in high H+ concentration medium and high salt medium than original strain and increased Na+ accumulation and decreased K+ accumulation. AtCCX1 was located in tonoplast in yeast. Transport essays were indicated by fluorescence SBFI and PBFI, respectively. Results show that ...

  9. Microvariability Detection of Mrk 421 Xu Chen, Shao Ming Hu & Di ...

    Indian Academy of Sciences (India)

    School of Space Science and Physics, Shandong University, 180 Cultural West Road,. Weihai, Shandong 264209, China. ∗ e-mail: husm@sdu.edu.cn. Abstract. BL Lac ... but no significant microvariability was detected during our observations. Key words. AGN—HBL—Mrk 421—microvariability. 1. Introduction. The BL Lac ...

  10. Metabolic and histopathological profile of Rattus norvegicus (Wistar) experimentally infected by Angiostrongylus cantonensis (Chen, 1935).

    Science.gov (United States)

    Garcia, Juberlan Silva; Lúcio, Camila dos Santos; Bonfim, Tatiane Cristina dos Santos; Junior, Arnaldo Maldonado; Tunholi, Victor Menezes; Tunholi-Alves, Vinícius Menezes; Mota, Esther Maria; Simões, Raquel de Oliveira; Santana, André Campos; Hooper, Cleber; Pinheiro, Jairo; Bóia, Marcio Neves

    2014-02-01

    Eosinophilic meningitis is a disease characterized by increased eosinophils in the cerebrospinal fluid (CSF), which is the most commonly caused by invasion of the central nervous system by helminths, as occurs in Angiostrongylus cantonensis infections. The rodent Rattus norvegicus is the definitive natural host and humans act as accidental hosts and can become infected by eating raw or undercooked snails or food contaminated with infective L3 larvae. Recently in Brazil there have been four cases of eosinophilic meningitis due to ingestion of infected Achatina fulica. To evaluate biochemical and histopathological changes caused by this parasite, R. norvegicus were experimentally infected with 100 L3 larvae of A. cantonensis. After the anesthetic procedure, serum from the rodents was collected from the inferior vena cava for evaluation of the levels of aspartate aminotransferase (AST), alanine aminotransferase (ALT), alkaline phosphatase (ALKP), gamma-glutamyl transferase (GGT), total protein and its fractions. During the necropsy, the liver was collected and weighed. Then a 1-g fragment was extracted from the major lobe to quantify the hepatic glycogen and fragment remainder was taken from the same lobe and fixed in Milloning's formalin for histopathological examination. Additionally, helminths were collected from the brain and lungs of the rodents. The activities of AST, ALT, ALKP and GGT in the serum and hepatic glycogen increased in response to infection, while the levels of globulin and total protein increased only in the eighth week of infection and there was a reduction in the levels of serum glucose. Albumin and bilirubin concentrations remained stable during the experiment. Infection with A. cantonensis caused metabolic and histopathological changes in the rodents. This study can contribute to a better understanding of the relationship between A. cantonensis and R. norvegicus. Copyright © 2013 Elsevier Inc. All rights reserved.

  11. VizieR Online Data Catalog: Red giant star sample from SDSS (Chen+, 2014)

    Science.gov (United States)

    Chen, Y. Q.; Zhao, G.; Carrell, K.; Zhao, J. K.; Tan, K. F.; Nissen, P. E.; Wei, P.

    2017-05-01

    Based on the SDSS DR9 database, we selected stars with (g-r)0 color in the range of 0.1 to 1.0 mag, and log g less than 3.5 dex for each metallicity bin ranging from [Fe/H]AJ....136.2022L, 2008, J/AJ/136/2050, 2011, J/AJ/141/90; Allende Prieto et al. 2008AJ....136.2070A; Smolinski et al. 2011, J/AJ/141/89). As described in Ahn et al. (2012ApJS..203...21A), the updated SSPP adopts a much-improved color-temperature relation from the InfraRed Flux Method Casagrande et al. (2010, J/A+A/512/A54), and the estimates of surface gravity and metallicity have been thoroughly recalibrated based on results from high-resolution observations. An estimate of the internal uncertainties of the SSPP is ~50 K for Teff, ~0.12 dex for log g, and ~0.10 dex for [Fe/H]. In order to avoid early-type stars, we limit the stars to have SSPP temperatures from 3000 K to 10000 K and a signal-to-noise ratio larger than 10. (1 data file).

  12. VizieR Online Data Catalog: S2CLS: multiwavelength counterparts to SMGs (Chen+, 2016)

    Science.gov (United States)

    Chen, C.-C.; Smail, I.; Ivison, R. J.; Arumugam, V.; Almaini, O.; Conselice, C. J.; Geach, J. E.; Hartley, W. G.; Ma, C.-J.; Mortlock, A.; Simpson, C.; Simpson, J. M.; Swinbank, A. M.; Aretxaga, I.; Blain, A.; Chapman, S. C.; Dunlop, J. S.; Farrah, D.; Halpern, M.; Michalowski, M. J.; van der Werf, P.; Wilkinson, A.; Zavala, J. A.

    2016-05-01

    The SCUBA-2 data at 850um in the UDS field were taken as part of the SCUBA-2 Cosmology Legacy Survey (S2CLS). The full data reduction steps are described fully in J. E. Geach et al. (2016, in preparation). In total we detect 1088 submillimeter sources at >=3.5σ within the region where rms noise is =4.0σ, for which we expect a false detection rate of ~1% based on simulations and source extractions on negative signals. We also define a supplementary sample of 372 submillimeter sources that are detected at 3.5-4.0σ and have a false detection rate of ~10%. In this paper, we provide counterpart candidates for both main and supplementary samples; however, the scientific analyses were performed on the main sample. We have carried out ALMA follow-up observations at 870um on 30 of the brighter SCUBA-2 sources in a Cycle 1 project 2012.1.00090.S (Simpson et al. 2015ApJ...807..128S, 2015ApJ...799...81S). The K-band-based multiwavelength photometry adopted in this paper is based on the UDS data release 8 (DR8) of the UKIRT Infrared Deep Sky Survey (UKIDSS; Lawrence et al. 2007, see II/319). The VLA radio observations at 1.4GHz (20cm) were carried out by the project UDS20 (V. Arumugam et al. 2016, in preparation), which comprises a mosaic of 14 pointings covering a total area of ~1.3deg2 centered on the UDS. The ~1 square degree UDS field contains a rich set of ancillary data (see section 2 for further details). (2 data files).

  13. Peculiar Physical Properties of HST-1 in M87 Y. J. Chen , G.-Y. Zhao ...

    Indian Academy of Sciences (India)

    This work was supported in part by the grants 10625314, 10633010 and 10821302,. KJCX2-YW-T03, 2007CB815405, the CAS/SAFEA International Partnership Pro- gram for Creative Research Teams, and the Science and Technology Commission of. Shanghai Municipality (09ZR1437400). References. Acciari, V. A. et al.

  14. Calibrating the Shan-Chen lattice Boltzmann model for immiscible displacement in porous media

    DEFF Research Database (Denmark)

    Christensen, Britt Stenhøj Baun; Schaap, M.G.; Wildenschild, D.

    2006-01-01

    physical system; in this case observed oil-water displacement experiments. For this purpose, we use simple, well-characterized, two-fluid-phase systems that furthermore function as a test of the code. The calibrated model is shown to produce realistic capillary pressures, within the pressure range...

  15. Effects of different cleaning treatments on heavy metal removal of Panax notoginseng (Burk) F. H. Chen.

    Science.gov (United States)

    Dahui, Liu; Na, Xu; Li, Wang; Xiuming, Cui; Lanping, Guo; Zhihui, Zhang; Jiajin, Wang; Ye, Yang

    2014-01-01

    The quality and safety of Panax notoginseng products has become a focus of concern in recent years. Contamination with heavy metals is one of the important factors as to P. notoginseng safety. Cleaning treatments can remove dust, soil, impurities or even heavy metals and pesticide residues on agricultural products. But effects of cleaning treatments on the heavy metal content of P. notoginseng roots have still not been studied. In order to elucidate this issue, the effects of five different cleaning treatments (CK, no treatment; T1, warm water (50°C) washing; T2, tap water (10°C) washing; T3, drying followed by polishing; and T4, drying followed by tap water (10°C) washing) on P. notoginseng roots' heavy metal (Cu, Pb, Cd, As and Hg) contents were studied. The results showed that heavy metal (all five) content in the three parts all followed the order of hair root > rhizome > root tuber under the same treatment. Heavy metal removals were in the order of Hg > As > Pb > Cu > Cd. Removal efficiencies of the four treatments were in the order of T2 > T1 > T3 > T4. Treatments (T1-T4) could decrease the contents of heavy metal in P. notoginseng root significantly. Compared with the requirements of WM/T2-2004, P. notoginseng roots' heavy metal contents of Cu, Pb, As and Hg were safe under treatments T1 and T2. In conclusion, the cleaning process after production was necessary and could reduce the content of heavy metals significantly. Fresh P. notoginseng root washed with warm water (T2) was the most efficient treatment to remove heavy metal and should be applied in production.

  16. VizieR Online Data Catalog: GTC transit light curves of WASP-52b (Chen+, 2017)

    Science.gov (United States)

    Chen, G.; Palle, E.; Nortmann, L.; Murgas, F.; Parviainen, H.; Nowak, G.

    2017-04-01

    We provide here the transit light curves of the hot Jupiter WASP-52b obtained on the night of 2015/08/28 using the OSIRIS instrument at the 10.4-m GTC telescope. The data was obtained by using OSIRIS through a 40-arcsec broad slit with the R1000R grism. The white-color light curve covers the wavelength range of 515-905nm, with 755-765nm being excluded. The spectroscopic light curves contain 22 channels of 16.5nm, 3 channels of 1.6nm, and 1 channel of 1.8nm. We provide several auxiliary parameters of the observations, some of which we have used to correct the data from correlated noise, including the position drift of the stars on the CCD detector in spatial and dispersion direction, the relative change in the FWHM of absorption line (dispersion FWHM), seeing (spatial FWHM), air mass, and rotator angle. (3 data files).

  17. Die Beifuß-Ambrosie auf Ackerflächen - ein Problem?

    Directory of Open Access Journals (Sweden)

    Verschwele, Arnd

    2014-07-01

    Full Text Available Common ragweed (Ambrosia artemisiifolia is spreading on agricultural fields in Germany, mainly in Brandenburg and Bayern. Competitive crops like winter cereals and oilseed-rape can reduce growth of this plant better than spring crops. In maize or cereals a chemical control is possible, but problems may arise because of the late emergence of ragweed and its high ability to regrowth. In crops like sunflower or lupines herbicide choice is limited and thus preventive control measures are crucial. An integrated approach is needed in order to avoid yield losses and to stop the spreading of ragweed in Germany.

  18. Lanthanide metal-organic frameworks

    Energy Technology Data Exchange (ETDEWEB)

    Cheng, Peng (ed.) [Nankai Univ., Tianjin (China). Dept. of Chemistry

    2015-03-01

    This book contains the following nine chapters: lanthanide metal-organic frameworks: syntheses, properties, and potential applications (Stephen Fordham, Xuan Wang, Mathieu Bosch, Hong-Cai Zhou); 2. chiral lanthanide metal-organic frameworks (Weisheng Liu, Xiaoliang Tang); 3. Porous lanthanide metal-organic frameworks for gas storage and separation (Bin Li, Banglin Chen); 4. Luminescent lanthanide metal-organic frameworks (Xue-Zhi Song, Shu-Yan Song, Hong-Jie Zhang); 5. Metal-organic frameworks based on lanthanide clusters (Lian Chen, Feilong Jiang, Kang Zhou, Mingyan Wu, Maochun Hong); 6. metal-organic frameworks with d-f cyanide bridges: structural diversity, bonding regime, and magnetism (Marilena Ferbinteanu, Fanica Cimpoesu, Stefania Tanase); 7. transition-lanthanide heterometal-organic frameworks: synthesis, structures, and properties (Wei Shi, Ke Liu, Peng Cheng); 8: MOFs of uranium and the actinides (Juan Su, Jiesheng Chen); 9. Nanostructured and/or nanoscale lanthanide metal-organic frameworks (Zhonghao Zhang, Zhiping Zheng).

  19. 實徵研究/Information Literacy in the Workplace: A Cross-cultural Perspective/Yuhfen Diana Wu

    Directory of Open Access Journals (Sweden)

    Yuhfen Diana Wu Yuhfen Diana Wu

    2012-04-01

    Full Text Available This cross-cultural study has two main purposes: to investigate how information literacy is perceived in the workplace and to discover how employees obtain information to carry out their jobs in an effective and timely fashion. This project applies a mix of research methods, including site visits, interviews, and a survey. More than 120 participants from forty companies were involved in this study. They were from a wide variety of industries in Taiwan and Silicon Valley, in Northern California, where many companies base offices or operations from around the world. Major obstacles in conducting cross-continent research are cost, time demands, scheduling, and adaptation to local culture. In this global economy, cross-cultural and cross-border research will help educators, such as librarians, understand the complexity of skills expected in the workplace. Much has been written on information literacy, yet very few can relate how information literacy is applied in the workplace. This primary study sheds some light to help academic librarians reposition themselves as researchers-educators integral to student success. 本論文為一跨文化性的研究,具有兩個主要目的:一是探討在職場中對於資訊素養的認知;二是探討員工如何及時有效的獲取和應用資訊來執行自己的任務。本研究採用混合式研究方法,包括實地考察、訪談和問卷調查。研究對象來自北加州矽谷和臺灣40家企業的120多名員工,他們分別從事不同行業。其中許多世界級的跨國企業選擇矽谷或臺灣作為公司總部或世界營運樞紐。進行跨洲研究的主要阻礙包括經費、時間、行程安排與適應當地的文化。跨文化和跨國界的研究將有助於教育工作者,如圖書館員,了解職場上所需技能的複雜性。目前已出版許多關於資訊素養的文獻,僅少涉及職場上資訊素養的應用。由於學術圖書館員在學生的學習過程中扮演不可或缺的角色,此初步研究,可幫助學術圖書館員重新為自己定位。 頁次:84-104

  20. A computational exploration of the McCoy-Tracy-Wu solutions of the third Painlevé equation

    Science.gov (United States)

    Fasondini, Marco; Fornberg, Bengt; Weideman, J. A. C.

    2018-01-01

    The method recently developed by the authors for the computation of the multivalued Painlevé transcendents on their Riemann surfaces (Fasondini et al., 2017) is used to explore families of solutions to the third Painlevé equation that were identified by McCoy et al. (1977) and which contain a pole-free sector. Limiting cases, in which the solutions are singular functions of the parameters, are also investigated and it is shown that a particular set of limiting solutions is expressible in terms of special functions. Solutions that are single-valued, logarithmically (infinitely) branched and algebraically branched, with any number of distinct sheets, are encountered. The algebraically branched solutions have multiple pole-free sectors on their Riemann surfaces that are accounted for by using asymptotic formulae and Bäcklund transformations.

  1. Retraction: "Identification of Novel Biomarkers for Pancreatic Cancer Using Integrated Transcriptomics With Functional Pathways Analysis" by Zhang, X., Tong, P., Chen, J., Pei, Z., Zhang, X., Chen, W., Xu, J. and Wang, J.

    Science.gov (United States)

    2017-11-01

    The above article from the Journal of Cellular Physiology, published online on 10 March 2016 in Wiley Online Library as Early View (http://onlinelibrary.wiley.com/enhanced/doi/10.1002/jcp.25353/), has been retracted by agreement between Gary Stein, the journal's Editor-in-Chief, and Wiley Periodicals, Inc. The retraction has been agreed following an investigation at the University of Texas, MD Anderson Cancer Center, which confirmed that the article was submitted and approved for publication by Dr. Jin Wang without acknowledgement of NIH funding received or the consent and authorship of Dr. Ann Killary and Dr. Subrata Sen, with whom the manuscript was originally drafted. © 2016 Wiley Periodicals, Inc.

  2. Erste Erfahrungen mit RDA an wissenschaftlichen Universalbibliotheken in Deutschland - Ergebnisse aus Fokusgruppengesprächen mit Katalogisierenden

    Directory of Open Access Journals (Sweden)

    Heidrun Wiesenmüller

    2017-04-01

    Full Text Available Einige Monate nach dem Umstieg auf das neue Regelwerk "Resource Description and Access" (RDA wurden an 18 großen deutschen wissenschaftlichen Universalbibliotheken Fokusgruppengespräche mit Katalogisierererinnen und Katalogisierern durchgeführt. Die Katalogisierenden wurden u.a. befragt, wie sicher sie sich bei der Anwendung von RDA fühlen, was sie am neuen Regelwerk gut oder schlecht finden, wie sie den Aufwand im Vergleich zum früheren Regelwerk RAK einschätzen, welche Informations- und Hilfsmittel sie verwenden und wie sie zu den regelmäßigen Änderungen im Standard stehen. Der vorliegende Aufsatz dokumentiert die Ergebnisse der Gespräche.   Several months after the introduction of the new cataloging standard "Resource Description and Access" (RDA, focus-group interviews with catalogers were conducted at 18 large academic and state libraries in Germany. Among other things, the catalogers were asked how confident they feel in applying RDA, which aspects of the new cataloging code they like or do not like, how they estimate the expenditure of time in comparison to the former cataloging code RAK, which sources they use to get help or information, and what they think about the frequent changes to the new standard. The paper presents the results of these interviews.

  3. Helical Magnetic Fields in AGN Jets Y. J. Chen1,2,∗ , G.-Y. Zhao1,2 ...

    Indian Academy of Sciences (India)

    Abstract. We establish a simple model to describe the helical mag- netic fields in AGN jets projected on the sky plane and the line-of-sight. This kind of profile has been detected in the polarimetric VLBI observa- tion of many blazar objects, suggesting the existence of helical magnetic fields in these sources. Key words.

  4. Effect of temperature on excess post-exercise oxygen consumption in juvenile southern catfish (Silurus meridionalis Chen) following exhaustive exercise.

    Science.gov (United States)

    Zeng, Ling-Qing; Zhang, Yao-Guang; Cao, Zhen-Dong; Fu, Shi-Jian

    2010-12-01

    The effects of temperature on resting oxygen consumption rate (MO2rest) and excess post-exercise oxygen consumption (EPOC) after exhaustive exercise (chasing) were measured in juvenile southern catfish (Silurus meridionalis) (8.40±0.30 g, n=40) to test whether temperature has a significant influence on MO2rest, maximum post-exercise oxygen consumption rate (MO2peak) and EPOC and to investigate how metabolic scope (MS: MO2peak - MO2rest) varies with acclimation temperature. The MO2rest increased from 64.7 (10°C) to 160.3 mg O2 h(-1) kg(-1) (25°C) (PEPOC varied from 32.9 min at 10°C to 345 min at 20°C, depending on the acclimation temperatures. The MS values of the lower temperature groups (10 and 15°C) were significantly smaller than those of the higher temperature groups (20, 25 and 30°C) (PEPOC varied ninefold among all of the temperature groups and was the largest for the 20°C temperature group (about 422.4 mg O2 kg(-1)). These results suggested that (1) the acclimation temperature had a significant effect on maintenance metabolism (as indicated by MO2rest) and the post-exercise metabolic recovery process (as indicated by MO2peak, duration and magnitude of EPOC), and (2) the change of the MS as a function of acclimation temperature in juvenile southern catfish might be related to their high degree of physiological flexibility, which allows them to adapt to changes in environmental conditions in their habitat in the Yangtze River and the Jialing River.

  5. J. Chen1, Z.-Q. Shen1, H. Sudou3, S. Iguchi4, Y. Murata5

    Indian Academy of Sciences (India)

    4National Astronomical Observatory of Japan, Tokyo 181-8588, Japan. 5The Institute of Space and Astronautical Science, JAXA, Kanagawa 229-8510, Japan. 6Research Center for Space and Cosmic Evolution, Ehime University,. Matsuyama 790-8577, Japan. ∗ e-mail: gyzhao@shao.ac.cn. Abstract. It was argued that 3C ...

  6. Chem TV: Choices I, v. 1.5.1 (by B. A. Luceigh, P. Ngo, and J. Chen)

    Science.gov (United States)

    Kraig Steffen, L.

    1999-08-01

    CHEM TV: Sunland, CA, 1998. 24.95, students; 59.95, faculty. This CD-ROM presents a series of interactive overviews and drills for students of organic chemistry. The material covered is generally taught in the first semester. This suite is much more than a simple presentation of material and, for students sufficiently motivated to take the time and work with the problems, will provide valuable review. Five interactive spaces are provided: concentration drills that emphasize recall of related structures/names, reagents/reactions, and stereochemistry; a structural review based on epinephrine; interactive synthesis projects; arcade game reagent review; and a set of timed self-tests. The CD-ROM installed and ran without problem on a Power PC Mac and on a Pentium running Windows 95. The program did fail to run when a student reviewing it switched to a very new version of Windows Quick Time. Most of the drills ran without a problem, although at times it was unclear how to respond to queries. I turned off the music, which would be much less annoying if the loops were simply longer. Publishers are flooding the market with add-on computer-based materials for the various levels of chemistry. Many constitute little more than a stack of overheads. This is one that may be of sufficient value to warrant the extra cost. A large number of examples are provided for many of the areas covered. Most of the graphical interfaces are clear and easy to manipulate, with the exception of a couple of mechanistic screens that had hard-to-figure-out arrows. Two sections, or modules, are of special note. The first of these is the synthesis challenges, where students must choose reactants, reagents, and reaction conditions for a particular reaction. These synthesis problems are well thought out and can be challenging. It is unfortunate that there are only five of them. The Self-Tests module is also of great practical value, forcing students to work through a variety of topics (200 problems) with limited time allotted per test. The structures are clear and easy to view and include a large number of three-dimensional molecular models that help make the connection between simple line drawings and actual molecules. More feedback information on incorrect answers would be nice, although it is obvious that this can balloon into an unworkable situation if every possible "wrong" answer is considered. The structure summary, which uses a single complicated molecule to review a large range of structural topics, is a good integrated look at bonding, stereochemistry, and conformational analysis. The concentration game is informative, albeit a bit obtuse on a few of the answers! The selection drills, a shooting gallery game with various chemical targets, seems a bit silly, but then if one can learn to recognize all the major reducing agents by snagging butterflies with faux nets than this could be helpful! With its varying levels of difficulty, this set of modules should be accessible even to weaker students and yet will provide a challenge for the more advanced. A great future addition would be an interactive module builder that allows faculty to modify existing questions and add their own. How can one effectively use this program? The relatively low cost does make it accessible for individual students to purchase, perhaps as a "recommended" item for the class. Another very practical option is to purchase 5-10 copies (assuming a class size of around 30-40) and make them available through a common computer laboratory (or an appropriate network site-license arrangement) or for check-out to small groups of students. One drawback is that only about 1/3 of the major topics that fill the year in organic are covered. I have used some of the drills as in-class interactive examples with a projector and laptop. This type of interactive tutorial-quiz-based program is a welcome change from the simple textbook on a CD-ROM approach. Given easy access to computers and an environment that encourages individual and small-group interactions, I believe this program can be a worthwhile aid for students of organic chemistry.

  7. Methodology of Leaving America for Asia: Reading South Korea's Social Studies Textbooks through Chen Kuan-Hsing's Asia as Method

    Science.gov (United States)

    Rhee, Jeong-eun

    2013-01-01

    This project began as a content analysis of five South Korean high school Social Studies textbooks. Yet, it has evolved into an epistemological experiment to pursue the question of "what does it mean to leave America for Asia, at least methodologically, for the researcher who left Asia for America?" Using the textbooks as a mediating…

  8. Untersuchung ausgewählter Oberflächen-, Grund- und Bodenwasserproben auf Perchlorat in Deutschland: Erste Ergebnisse

    Science.gov (United States)

    Scheytt, Traugott J.; Freywald, Jessika; Ptacek, Carol J.

    2011-03-01

    Perchlorate is a component found in solid rocket fuels, explosives, fireworks, and road flares. In addition, perchlorate is a minor component of natural salt deposits in semiarid and arid regions. Discharge and storage areas as well as accidents are potential sources for perchlorate contamination of aquatic systems. Perchlorate has been detected in surface water and groundwater from several places worldwide. The aim of this study is to evaluate whether perchlorate occurs in surface water, groundwater, or soil leachate at selected sites in Germany. These sites include surface water from a military base in southern Germany, groundwater from a production site, and groundwater and soil leachate from a location where fireworks shows are performed regularly. Results show that perchlorate was detected in all surface water and groundwater samples with values around 1 μg/l. Highest values (up to 15,000 μg/l) were detected in pore waters of the "Maifeld" area in Berlin where soil was sampled immediately after a fireworks show.

  9. X-ray Time Lags in TeV Blazars X. Chen1,∗ , G. Fossati1, E. Liang1 ...

    Indian Academy of Sciences (India)

    #1: Homogeneous, steady rate, injection of high energy particles with power-law distribution. The flare is caused by an increase/decrease of the maximum electron energy γmax, following an exponential (symmetric) time evolution. #2: Homogeneous mild diffusive particle acceleration mechanism is active in the blob for a ...

  10. Trichodina nobilis Chen, 1963 and Trichodina reticulata Hirschmann et Partsch, 1955 from ornamental freshwater fishes in Brazil.

    Science.gov (United States)

    Martins, M L; Marchiori, N; Roumbedakis, K; Lami, F

    2012-05-01

    In the present work Trichodina reticulata and T. nobilis (Ciliophora: Trichodinidae) are morphologically characterised from ornamental freshwater fish culture in the State of Santa Catarina, Brazil. The prevalence of infection and a list of comparative measurements are discussed. We examined "southern platyfish" Xiphophorus maculatus (n = 35), "goldfish" Carassius auratus (n = 31), "guppy" Poecilia reticulata (n = 20), "sailfin molly" Poecilia latipinna (n = 6), "beta" Betta splendens (n = 2) and "spotted headstander" Chilodus punctatus (n = 1). After being anesthetised in a benzocaine solution, fishes were examined for parasitological evaluation. A total of 51.57% fishes were parasitised by Trichodina spp. Carassius auratus was the most parasitised species, followed by X. maculatus and P. reticulata. Beta splendens, C. punctatus and P. latipinna were not parasitised by any trichodinid species. Two species of Trichodina were collected from the skin of fish: T. nobilis was found in C. auratus, P. reticulata and X. maculatus and T. reticulata was only observed in C. auratus. The importance of adequate handling in ornamental fish culture are also discussed.

  11. Embryo development in association with asymbiotic seed germination in vitro of Paphiopedilum armeniacum S. C. Chen et F. Y. Liu.

    Science.gov (United States)

    Zhang, Yan-Yan; Wu, Kun-Lin; Zhang, Jian-Xia; Deng, Ru-Fang; Duan, Jun; Teixeira da Silva, Jaime A; Huang, Wei-Chang; Zeng, Song-Jun

    2015-11-12

    This paper documents the key anatomical features during the development of P. armeniacum zygotic embryos and their ability to germinate asymbiotically in vitro. This study also examines the effect of media and seed pretreatments on seed germination and subsequent seedling growth. Seeds collected from pods 45 days after pollination (DAP) did not germinate while 95 DAP seeds displayed the highest seed germination percentage (96.2%). Most seedlings (50%) developed to stage 5 from 110 DAP seeds whose compact testa had not yet fully formed. Suspensor cells were vacuolated, which enabled the functional uptake of nutrients. The optimum basal medium for seed germination and subsequent protocorm development was eighth-strength Murashige and Skoog (1/8MS) for 95 DAP seeds and ¼MS for 110 DAP seeds. Poor germination was displayed by 140 DAP seeds with a compact testa. Pretreatment of dry mature seeds (180 DAP) with 1.0% sodium hypochlorite solution for 90 min or 40 kHz of ultrasound for 8 min improved germination percentage from 0 to 29.2% or to 19.7%, respectively. Plantlets that were at least 5 cm in height were transplanted to a Zhijing stone substrate for orchids, and 85.3% of plantlets survived 180 days after transplanting.

  12. Remedial Investigation/Baseline Risk Assessment for the Ravines and Beach Area Study areas of the Surplus Operable Unit, Fort Sheridan, Illinois, Volume 3 - BRA Text and BRA Appendices A-L

    Science.gov (United States)

    1998-04-13

    1983. Chronic arsenic poisoning in the north of Mexico . Hum. Toxicol. 2:121-133. Chen, C.J.; Chuang, Y.C.; Lin, T.M.; Wu, H.Y. 1985. Malignant...Coahuila, Mexico . Revista de la Facultad de Medicina de Torreon 12:16. (Cited in ATSDR 1989). Schaumburg, H.A. 1980. Failure to produce arsenic...feeding of large doses of beryllium carbonate (0.1-0.5%, 1-5 g/kg of food) to young animals produced rickets (Guyatt et al., 1933; Jacobson, 1933

  13. Northeast Artificial Intelligence Consortium (NAIC). Volume 3. The Versatile Maintenance Expert System (VMES)

    Science.gov (United States)

    1990-12-01

    College ( CUNY ) New York, NY 1987 Michael J. Almeida Assistant Professor Penn State University Dept. of Computer Science Whitmore Lab University Park...Tien Kingsbury, Linda A. Williams, Francine Delgado, Diane M. Liu, Paul C-W Wu, W-C Jevons Fenrich, Richard Menon, Rajeev Artificial Intelligence...He, Hung Chyi Liu, Peter (Sai-Ming) Su, Suyuan C. Hsu, An-Mei Lo, Yu Li Yang, Lien Jang Jou, Chen-Jye Lung, Hsi-Hong Yao, Jo-Lan Kellick, Diane

  14. Correlation between radioactivity and chemotherapeutics of the 111In-VNB-liposome in pharmacokinetics and biodistribution in rats

    OpenAIRE

    Tsai TH; Lee TW; Chang TJ; Ho CL; Chen LC; Wu YT; Huang CM; Chang CH; Lee WC

    2012-01-01

    Wen-Chuan Lee1,*, Chih-Hsien Chang2,3,*, Chih-Min Huang1, Yu-Tse Wu1, Liang-Cheng Chen2, Chung-Li Ho2, Tsui-Jung Chang2, Te-Wei Lee2, Tung-Hu Tsai1,41Institute of Traditional Medicine, School of Medicine, National Yang-Ming University, Taipei, 2Division of Isotope Application, Institute of Nuclear Energy Research, Taoyuan, 3Department of Biomedical Imaging and Radiological Sciences, National Yang-Ming University, Taipei, 4Department of Education and Research, Taipei City Hospital, Taipei, Tai...

  15. The Petitioning System: A Major Challenge to “Social Harmony”? and Can Taiwan’s opposition reconstruct itself?

    OpenAIRE

    Tran Dai, Candice; Kilian, Hubert

    2012-01-01

    Analysis by Candice Tran Dai based on:• Wu Yang, “Debate at the highest level of the CCP on the question of maintaining or abandoning the petition system,” Chengming, 2 May 2009• Yu Jianrong, “University specialisation in ‘petitions’: What needs to be studied,” Nanfang Zhoumo, 10 June 2009Analysis by Hubert Kilian based on:• “Internal tensions in the DPP: Pandora’s box opened in executive committee,” Lianhe bao - United Daily News, 9 June 2009, editorial pages.• “When Chen Chu was in prison f...

  16. Cache Sharing and Isolation Tradeoffs in Multicore Mixed-Criticality Systems

    Science.gov (United States)

    2015-05-01

    common practice today to allow hardware com- ponents such as last-level caches (LLCs) and memory con- trollers to be shared across cores; this can be...CAMA: A pre- dictable cache -aware memory allocator. In ECRTS ’11. [10] R. Kessler and M. Hill. Page placement algorithms for large real- indexed...allocation for real-time) cache design. In RTSS ’89. [14] L. Liu, Z. Cui, M. Xing, Y. Bao, M. Chen, and C. Wu. A software memory partition approach for

  17. Mesoporous bioactive glass surface modified poly(lactic-co-glycolic acid) electrospun fibrous scaffold for bone regeneration

    OpenAIRE

    Chen, Shijie; Jian, Zhiyuan; Huang, Linsheng; Xu, Wei; Liu, Shaohua; Song, Dajiang; Wan, Zongmiao; Vaughn, Amanda; Zhan, Ruisen; Zhang, Chaoyue; Wu, Song; Hu, Minghua; Li, Jinsong

    2015-01-01

    Shijie Chen,1,* Zhiyuan Jian,2,* Linsheng Huang,2,* Wei Xu,3,* Shaohua Liu,4 Dajiang Song,3 Zongmiao Wan,3 Amanda Vaughn,5 Ruisen Zhan,1 Chaoyue Zhang,1 Song Wu,1 Minghua Hu,6 Jinsong Li1 1Department of Orthopaedics, The Third Xiangya Hospital of Central South University, Changsha, Hunan, People’s Republic of China; 2The First General Surgery Department of Shiyan Taihe Hospital Affiliated to Hubei University of Medicine, Shiyan, People’s Republic of China; 3Department of ...

  18. Nobel laureate T.D. Lee at CERN

    CERN Multimedia

    2007-01-01

    On 30 August, Professor T.D. Lee, who received the Nobel Prize for Physics in 1957, gave a seminar at CERN on symmetry and asymmetry in electroweak interactions, 50 years after the discovery of the non-conservation of parity. In 1956, Tsung-Dao Lee postulated with Chen Ning Yang that parity is not conserved in weak interactions, and suggested several experiments to demonstrate this. The following year, an experiment led by Chien-Shiung Wu proved this prediction and, soon after, T.D. Lee and Chen Ning Yang were awarded the Nobel Prize for Physics. Still very active at over 80 years of age, T.D. Lee pursues his theory work to this day.

  19. Photoluminescent (PL) or electroluminescent (EL) quantum dots for display, lighting, and photomedicine (Conference Presentation)

    Science.gov (United States)

    Dong, Yajie

    2017-02-01

    Quantum dots (QDs) have gone through a long journey before finding their ways into the display field. This talk will briefly touch on the history before trying to answer several key questions related to QDs applications in display: What are QDs? How are they made? What properties do they have and Why? How can these properties be used to improve color and efficiency of display, in either photoluminescence (PL) or electroluminescence (EL) mode? And what are the remaining challenges for QDs wide adoption in display industry? Lastly, some most recent progresses in our UCF lab at both PL and EL fronts will be highlighted. For PL, a cadmium-free perovskite-polymer composite films with exceptionally narrow emission green peaks (FWHM 20 nm) and good water and thermal stability will be reported. Together with red quantum dots or PFS/KSF phosphors as down-converters for blue LEDs, a white-light source with 95% Rec. 2020 color gamut was demonstrated [1]. For EL, red quantum dot light emitting devices (QLEDs) with record luminance of 165,000 Cd/m2 has been obtained at a current density of 1000 mA/cm2 with a low driving voltage of 5.8 V and CIE coordinates of (0.69, 0.31). [2] The potential of using these QLEDs for light sources for integrated sensing platform [3] or high efficiency, high color quality hybrid white OLED [4] will be discussed. [1] Y. N. Wang, J. He, H. Chen, J. S. Chen, R. D. Zhu, P. Ma, A. Towers, Y. Lin, A. J. Gesquiere, S. T. Wu, Y. J. Dong. Ultrastable, Highly Luminescent Organic-Inorganic Perovskite - Polymer Composite Films, Advanced Materials, accepted, (2016). [2] Y. J. Dong, J.M. Caruge, Z. Q. Zhou, C. Hamilton, Z. Popovic, J. Ho, M. Stevenson, G. Liu, V. Bulovic, M. Bawendi, P. T. Kazlas, S. Coe-Sullivan, and J. Steckel Ultra-bright, Highly Efficient, Low Roll-off Inverted Quantum-Dot Light Emitting Devices (QLEDs). SID Symp. Dig. Tech. Pap. 46, 270-273 (2015). [3] J. He, H. Chen, S. T. Wu, and Y. J. Dong, Integrated Sensing Platform Based on Quantum

  20. Comparative trophodynamics of anchovy Engraulis encrasicolus ...

    African Journals Online (AJOL)

    Comparative trophodynamics of anchovy Engraulis encrasicolus and sardine Sardinops sagax in the southern Benguela: are species alternations between small pelagic fish trophodynamically mediated? CD van der Lingen, L Hutchings, JG Field ...

  1. Impacts of land use change scenarios on hydrology and land use patterns in the Wu-Tu watershed in Northern Taiwan

    NARCIS (Netherlands)

    Lin Yu-Pin,; Hong Nien-Ming,; Wu Pei-Jung,; Wu Chen-Fa,; Verburg, P.H.

    2007-01-01

    Developing an approach for simulating and assessing land use changes and their effects on land use patterns and hydrological processes at the watershed level is essential in land use and water resource planning and management. This study provided a novel approach that combines a land use change

  2. 圖書館事業與交流/The Relationship of Leadership Development and Learning Organization Dimensions/Connie K. Haley, Yuhfen Diana Wu

    Directory of Open Access Journals (Sweden)

    Connie K. Haley, Yuhfen Diana Wu Connie K. Haley, Yuhfen Diana Wu

    2011-10-01

    Full Text Available This research examined the relationship among learning organization dimensions, leadership development, employee development, and their interactions with two demographic variables (gender and ethnicity in the context of libraries. The researchers conducted a multivariate analysis of the variance to assess the differences by leadership training groups (low training hours vs. high training hours, or by gender; and by workplace training groups (low vs. high, or by ethnicity (white vs. all others on a linear combination of the seven dimensions of the learning organization. A conclusive summary is provided along with contributive discussion. Implications and contributions to librarians are discussed in addition to future research recommendations. Also included are conclusive final thoughts accompanied by the limitations of this research. 本研究旨在探討美國圖書館界學習型組織,領導智能與員工發展之間的關系,以及它們與兩項人口變量(性別、種族)的相互作用。作者採用線性組合研究了學習型組織的七個範疇,並且使用多變量變異數分析方法來評估領導智能培訓組的差異(培訓時數多寡對比),在職培訓組的差異(培訓時數多寡對比),及種族的差異(白人或其他族裔對比)。除了討論未來研究方向的建議,作者並提供人力資源發展工作者和圖書館員一些啟示。研究最後提出作者的想法及本研究的侷限性。 頁次:146-165

  3. Ambient air particulate concentrations and metallic elements principal component analysis at Taichung Harbor (TH) and WuChi Traffic (WT) near Taiwan Strait during 2004-2005.

    Science.gov (United States)

    Fang, Guor-Cheng; Wu, Yuh-Shen; Wen, Chih-Chung; Huang, Shih-Han; Rau, Jui-Yeh

    2006-09-01

    The purpose of this study is to characterize metallic elements associated with atmospheric particulate matter of total suspended particulate (TSP), fine particle (particle matter with aerodynamical diameter metallic elements Fe and Zn. And in WT sampling site, higher correlation coefficients displayed on total suspended particulates of metallic elements Fe and Zn, Fe and Mn. Ambient airborne particle principal component analysis of metallic metals was used to identify the possible pollutant sources in this study. At the TH sampling site, 50.81% of the total variance of the data was observed in factor 1. Higher loading of Fe (0.86), Zn (0.79), Pb (0.76), and Mn (0.68) were contributed by traffic emission and the soil source. At the WT sampling site, factor 1 explained 53.74% of the total variance of the data and had high loading for Zn (0.86) and Cu (0.85), which were identified as industrial/traffic emission sources.

  4. Traditional Chinese Medicine and herbal hepatotoxicity: a tabular compilation of reported cases.

    Science.gov (United States)

    Teschke, Rolf; Zhang, Li; Long, Hongzhu; Schwarzenboeck, Alexander; Schmidt-Taenzer, Wolfgang; Genthner, Alexander; Wolff, Albrecht; Frenzel, Christian; Schulze, Johannes; Eickhoff, Axel

    2015-01-01

    Traditional Chinese Medicine (TCM) with its focus on herbal use became popular worldwide. Treatment was perceived as safe, with neglect of rare adverse reactions including liver injury. To compile worldwide cases of liver injury by herbal TCM, we undertook a selective literature search in the PubMed database and searched for the items Traditional Chinese Medicine, TCM, Traditional Asian Medicine, and Traditional Oriental Medicine, also combined with the terms herbal hepatotoxicity or herb induced liver injury. The search focused primarily on English-language case reports, case series, and clinical reviews. We identified reported hepatotoxicity cases in 77 relevant publications with 57 different herbs and herbal mixtures of TCM, which were further analyzed for causality by the Council for International Organizations of Medical Sciences (CIOMS) scale, positive reexposure test results, or both. Causality was established for 28/57 different herbs or herbal mixtures, Bai Xian Pi, Bo He, Ci Wu Jia, Chuan Lian Zi, Da Huang, Gan Cao, Ge Gen, Ho Shou Wu, Huang Qin, Hwang Geun Cho, Ji Gu Cao, Ji Xue Cao, Jin Bu Huan, Jue Ming Zi, Jiguja, Kudzu, Ling Yang Qing Fei Keli, Lu Cha, Rhen Shen, Ma Huang, Shou Wu Pian, Shan Chi, Shen Min, Syo Saiko To, Xiao Chai Hu Tang, Yin Chen Hao, Zexie, and Zhen Chu Cao. In conclusion, this compilation of liver injury cases establishes causality for 28/57 different TCM herbs and herbal mixtures, aiding diagnosis for physicians who care for patients with liver disease possibly related to herbal TCM.

  5. Ökologisch bewirtschaftete Ackerflächen - eine ökologische Leistung? Ein ergebnisorientierter Ansatz für die Praxis

    OpenAIRE

    Braband, Dorothee; Elsen, Thomas van

    2003-01-01

    Zielorientierte bzw. ergebnisorientierte Ansätze zur Erfassung ökologischer Leistungen der Landwirtschaft könnten künftig eine wesentliche Grundlage für die Bemsessung landwirtschaftlicher Direktzahlungen werden. Als ökologische Leistungen sollte alles abgegolten werden, was über die gute fachliche Praxis im Rahmen der landwirtschaftlichen Fachrechte und des Bundesnaturschutzgestz hinausgeht.

  6. AUTUN, MANÉ-VÉCHEN ET VIEUX : L’APPORT DE TROIS SITES MAJEURS À LA CONNAISSANCE DE L’ARTISANAT DU STUC EN GAULE ROMAINE

    Directory of Open Access Journals (Sweden)

    Julien Boislève

    2011-10-01

    Full Text Available La découverte et l’étude récente d’importants lots de stucs sur les sites de la villa de Mané-Véchenen Plouhinec (Morbihan et du “palais“ urbain du centre hospitalier à Autun (Saône-et-Loire constituent un apport considérable à notre connaissance d’un artisanat relativement méconnu en Gaule: le stuc. Parallèlement, le réexamen de collections plus anciennes sur la domus de Vieux (Calvados a permis la réinterprétation de décors laissant une place considérable et parfois inattendue au relief. Relativement complets, et pour certains restituables, ces décors éclairent un usage du stuc assez différent de celui connu en Italie et permettent d’identifier certaines modes décoratives typiquement provinciales.

  7. Untersuchungen an einer Kolbenexpansionsmaschine mit integrierten Wärmeübertragerflächen (Wärmeübertrager-Expander) zur Realisierung eines neuartigen Neon-Tieftemperatur-Prozesses

    OpenAIRE

    Fredrich, Ole

    2005-01-01

    Viele Anwendungen der Hochtemperatur-Supraleitung arbeiten vorteilhaft im Temperaturbereich zwischen 30 - 50 K. Für diesen Temperaturbereich existieren nur wenige geeignete Kältemaschinen mit kleiner Kälteleistung (1-2 W) u. gutem Wirkungsgrad. Neon ist aufgrund seiner Stoffeigenschaften ein hervorragendes Kältemittel für diesen Temperaturbereich, wie z.B. anhand einer realisierten Joule-Thomson (JT) Demonstrationsanlage deutlich wird. Als Ergebnis einer Prozessanalyse wird ein Kreislauf vorg...

  8. Methodology of Leaving America for Asia: Reading South Korea’s Social Studies Textbooks through Chen Kuan-Hsing’s Asia as Method

    Directory of Open Access Journals (Sweden)

    Joungh-eun Rhee

    2013-10-01

    Full Text Available This project began as a content analysis of five South Korean high school Social Studies textbooks. Yet, it has evolved into an epistemological experiment to pursue the question of “what does it mean to leave America for Asia, at least methodologically, for the researcher who left Asia for America?” Using the textbooks as a mediating site, therefore, I articulate a process that engages with, moves toward, and develops deimperializing methodology. More specifically, I interweave Kuan-Hsing Chen’s Asia as Method: Toward Deimperialization (2010 with my data by analyzing the data through Asia as Method and reading and practicing Asia as Method as methodology. This allows me to move away from fixating on the West as a reference point even through my critique. Rather, I work to produce geo-historically grounded knowledge for specific interventions at this mediating site toward the movements of decolonization, de-cold war, and deimperialization. In the process, I discuss how Asia as Method as methodology provokes political, psychological, and social engagements of everyday, multiplies reference points for knowledge production, and requires a researcher to re-work on one’s subjectivity inevitably constituted by imperialism.

  9. Spinnen ökologischer Ausgleichsflächen in den Schweizer Kantonen Aargau und Schaffhausen (Arachnida: Araneae – mit Anmerkungen zu Phrurolithus nigrinus (Corinnidae

    Directory of Open Access Journals (Sweden)

    Blick, Theo

    2008-07-01

    Full Text Available The spider fauna of open habitats adjacent to arable land was investigated in northern Switzerland. The three habitat types were (1 herbaceous edges of fields (Sa, (2 fallow land sowed with flowers (BB, and (3 grass borders of fields (GS. Four funnel pitfall traps (10 cm diameter were used to catch spiders in three stripe-types in two geographical regions in two years over 5 weeks in May and June: in total 12 sets of data. Spider species typical for open habitats were dominant, mostly lycosids (6 of the 10 most active species. The results were analysed together with environmental factors using a canonical correspondence analysis (CCA and spiders were compared with carabid beetles (Coeloptera: Carabidae. Geographical region, though not very distant, had the largest influence on both spiders and carabids. The age and type of the habitats had a stronger influence on spiders than on carabids. In spiders a larger part of the total variance was explained by the analysed factors. Finally we discuss briefly a remarkable spider species. A review of all known records of Phrurolithus nigrinus in Switzerland and Germany, together with adjacent regions in France, is given. Its phenology is indicated, its habitat discussed and the overall distribution within Europe is listed.

  10. Diskrepanz: Die EU-Frauenpolitik zwischen Deregulierung und Gleichheitsansprüchen Internal Discrepancies: EU Women’s Policies between Deregulation and Claims to Equality

    Directory of Open Access Journals (Sweden)

    Ingrid Biermann

    2003-03-01

    Full Text Available In von neun Autorinnen verfassten Beiträgen gibt der Band Einblicke in zentrale Felder der EU-Politik: die europäische Wirtschafts- und Währungsunion (EWWU, die Strukturpolitik, die Gleichstellungspolitik und das Gender Mainstreaming, die Osterweiterung sowie die Ausarbeitung einer europäischen Verfassung. Damit werden wesentliche Teile des Maastricht-Vertrags (1992, des Amsterdamer Vertrags (1997 und des Nizza-Vertrags (2000 behandelt. Hierdurch bildet dieser Band eine wichtige Grundlage für die Diskussion über die Frauenpolitik der EU.This anthology, consisting of nine essays written by women authors, offers insights into central areas of EU politics: the European Economic and Currency Union, structural policies, policies dealing with gender equality, the expansion of the EU, as well as the creation of a new European constitution. These policies include relevant parts of the 1992 Maastricht Treaty, the 1997 Treaty of Amsterdam, and the 2000 Treaty of Nizza. The information and insights presented here make this book an important basis for any discussions about EU women’s policies.

  11. Elektrochemische Kontrolle von Reibung auf Goldoberflächen in wässrigen Elektrolyten und ionischen Flüssigkeiten

    OpenAIRE

    Hausen, Florian

    2012-01-01

    Die Kontrolle von Reibung auf kleiner Skala ist von fundamentaler Bedeutung, insbesondere im Hinblick auf die fortschreitende Miniaturisierung von mechanischen Bauteilen. Im Rahmen dieser Arbeit wurden hochaufgelöste Experimente zur Reibung in ultrasauberen Flüssigkeiten durchgeführt, um so die Möglichkeiten der Kontrolle von Reibungskräften auf Gold in wässrigen Elektrolyten und ionischen Flüssigkeiten auf atomare Mechanismen zurückführen zu können. Die Kombination der Rasterkraftmikroskopie...

  12. Evaluation des Comet Assays bei neutralem pH zur Detektion von Alpha-Partikel induzierten DNA-Doppelstrangbrüchen

    OpenAIRE

    Hofbauer, Daniela

    2011-01-01

    Das Ziel der Arbeit war die Darstellung von initialen DNA-Schäden in Tumorzellen, verursacht durch Bestrahlung mit Alpha-Partikeln. Mit Hilfe des Comet Assays lassen sich sowohl DNA-Einzelstrangbrüche als auch -Doppelstrangbrüche auf dem Niveau einer einzelnen Zelle darstellen. Als Alpha-Strahler wurde Americium-241 verwendet. Für vergleichende Untersuchungen wurde auch der Gamma-Emitter Caesium-137 eingesetzt. Auf Grund von technischen Problemen bei der Durchführung sowohl des neutralen als ...

  13. How Structural Deficiencies Hamper Estonia’s Catching-up Process. Strukturschwächen als Hemmnis für Estlands Aufholprozess

    Directory of Open Access Journals (Sweden)

    Klaus Schrader

    2016-10-01

    Full Text Available Estonia is widely regarded as a paramount example for a successful transformation of a socialist economic system to a functioning market economy. Against the backdrop of this positive image which contrasts strongly with the crisis scenarios in Southern Europe the remaining problems of Estonia are often ignored. Estonia has hardly succeeded in catching-up economically with the richer countries of the EU. In this paper the authors raise the question why the catching-up process of Estonia is not as successful as it could have been expected from the policy performance during the last decades. It turns out that Estonia faces a serious productivity problem, particularly in the manufacturing sector producing tradable goods which is normally the driving engine behind economic and technological catching-up. The Estonian economy has failed to undergo the necessary structural change towards technologically more advanced employment structures and export patterns. Accordingly, Estonian economic policy needs to create a suitable business environment to support this kind of structural change.

  14. Jasmonic acid and methyl dihydrojasmonate enhance saponin biosynthesis as well as expression of functional genes in adventitious roots of Panax notoginseng F.H. Chen.

    Science.gov (United States)

    Li, Jinxin; Wang, Juan; Wu, Xiaolei; Liu, Dahui; Li, Jing; Li, Jianli; Liu, Shujie; Gao, Wenyuan

    2017-03-01

    Panax notoginseng, an important herbal medicine, has wide uses for its bioactive compounds and health function. In this work, we compared the content of saponin in cultivation and adventitious root. The total content of saponins in adventitious root (8.48 mg⋅g(-1) ) was found lower than in the native one (3-year-old) (34.34 mg⋅g(-1) ). To enhance the content of bioactive compounds, we applied elicitors jasmonic acid (JA) and methyl dihydrojasmonate (MDJ) to the adventitious root culture. It was observed that the highest total content of saponins (71.94 mg⋅g(-1) ) was achieved after treatment with 5 mg⋅L(-1) JA, which was 2.09-fold higher than native roots and 8.45-fold higher than the control group. The findings from high-performance liquid chromatography-electrospray ionization-tandem mass spectrometry analysis showed that six new compounds were present after the treatment with the elicitors. Furthermore, we found that JA and MDJ significantly upregulated the expression of the geranyl diphosphate synthase, farnesyl diphosphate synthase, squalene synthase, squalene epoxidase, dammarenediol synthase, and CYP716A47 and CYP716A53v2 (CYP450 enzyme) genes; downregulated the expression of the cycloartenol synthase gene; and increased superoxide dismutase and peroxidase activities. © 2016 International Union of Biochemistry and Molecular Biology, Inc.

  15. Bya rog prog zhu, The raven crest : the life and teachings of bDe chen 'od gsal rdo rje treasure revealer of contemporary Tibet

    NARCIS (Netherlands)

    Terrone, Antonio

    2010-01-01

    This research starts from the historical assertion that notwithstanding their claim of increased religious tolerance, the dramatic post-Mao political campaigns have continued to weaken the pervasive force of religious faith, traditional monastery-centered religious power, religious leadership, and

  16. Infrared thermography fails to visualize stimulation-induced meridian-like structures: comment by Rixin Chen and Zhimai Lv and reply from Gerhard Litscher

    Science.gov (United States)

    2011-01-01

    A comment on G. Litscher: Infrared thermography fails to visualize stimulation-induced meridian-like structures. Biomed. Eng. OnLine 2005, 4:38 (15 June 2005), with a response by the author. PMID:21906400

  17. The effect of exercise training on the metabolic interaction between feeding and locomotion in the juvenile southern catfish (Silurus meridionalis Chen).

    Science.gov (United States)

    Li, Xiu-Ming; Cao, Zhen-Dong; Fu, Shi-Jian

    2010-11-01

    The southern catfish exhibits the largest decrease in critical swimming speeds (U(crit)) during digestion among the fish species that have been investigated. To test whether the maximum metabolic capacity of the southern catfish was improved after exercise training to alleviate the competitive interaction between digestion and swimming, we measured postprandial metabolic responses, U(crit) and oxygen consumption rates (MO(2)) during swimming in both fasting and digesting fish. Twenty-one days of training (50 min swimming at 60% U(crit) followed by 10 min chasing) did not produce significant differences in resting MO(2) (MO(2rest)) or postprandial peak MO(2) (MO(2peak)). However, it did result in a significant decrease in energy expenditure during digestion. Feeding caused a significant decrease in U(crit) and an increase in active MO(2) (MO(2active)), whereas training caused a significant increase in U(crit) but no significant change in MO(2active). Neither digestion nor training had a significant effect on metabolic scope (MO(2active)-MO(2rest)). Training had no interactive effect on postprandial changes in any measured variable, so we conclude that training did not alleviate the competitive interaction between digestion and swimming. Our results suggest that: (1) the metabolic capacity of nontrained fish cannot support the metabolic demands of both digestion and locomotion simultaneously, and swimming metabolism, therefore, is sacrificed to sustain digestion when feeding and locomotion are combined (digestion-prioritization mode); (2) the metabolic capacity and metabolic mode of competition did not change after training, but trained fish did exhibit improved swimming performance, possibly due to their increased rate of O(2) extraction.

  18. New World species of the genus Calliscelio Ashmead (Hymenoptera, Platygastridae, Scelioninae

    Directory of Open Access Journals (Sweden)

    Hua-yan Chen

    2017-01-01

    Full Text Available The genus Calliscelio Ashmead is presumed to be a diverse group of parasitoids of the eggs of crickets (Orthoptera: Gryllidae. A least one species has been found to be an important factor in depressing cricket pest populations. The New World species of Calliscelio are revised. Forty-two species are recognized, 3 are redescribed: C. bisulcatus (Kieffer, C. laticinctus Ashmead, C. rubriclavus (Ashmead, comb. n.; and 38 are described as new: C. absconditum Chen & Johnson, sp. n., C. absum Chen & Johnson, sp. n., C. alcoa Chen & Masner, sp. n., C. amadoi Chen & Johnson, sp. n., C. armila Chen & Masner, sp. n., C. bidens Chen & Masner, sp. n., C. brachys Chen & Johnson, sp. n., C. brevinotaulus Chen & Johnson, sp. n., C. brevitas Chen & Johnson, sp. n., C. carinigena Chen & Johnson, sp. n., C. crater Chen & Johnson, sp. n., C. crena Chen & Johnson, sp. n., C. eboris Chen & Johnson, sp. n., C. extenuatus Chen & Johnson, sp. n., C. flavicauda Chen & Johnson, sp. n., C. foveolatus Chen & Johnson, sp. n., C. gatineau Chen & Johnson, sp. n., C. glaber Chen & Masner, sp. n., C. granulatus Chen & Masner, sp. n., C. latifrons Chen & Johnson, sp. n., C. levis Chen & Johnson, sp. n., C. longius Chen & Johnson, sp. n., C. magnificus Chen & Masner, sp. n., C. migma Chen & Johnson, sp. n., C. minutia Chen & Johnson, sp. n., C. paraglaber Chen & Johnson, sp. n., C. pararemigio Chen & Masner, sp. n., C. prolixus Chen & Johnson, sp. n., C. punctatifrons Chen & Johnson, sp. n., C. remigio Chen & Masner, sp. n., C. ruga Chen & Johnson, sp. n., C. rugicoxa Chen & Masner, sp. n., C. sfina Chen & Johnson, sp. n., C. storea Chen & Johnson, sp. n., C. suni Chen & Johnson, sp. n., C. telum Chen & Johnson, sp. n., C. torqueo Chen & Johnson, sp. n., C. virga Chen & Johnson, sp. n. Four species are treated as junior synonyms of Calliscelio rubriclavus (Ashmead: Anteris nigriceps Ashmead, syn. n., Caloteleia marlattii Ashmead, syn. n., Caloteleia grenadensis Ashmead, syn. n

  19. List of Participants

    Indian Academy of Sciences (India)

    List of Participants. Margo Aller. Denis Bastieri. Xiongwei Bi. Weihao Bian. Vera Bychkova. Bo Chai. Jianling Chen. Xuhui Chen. Ye Chen. Zhifu Chen. Yongjun Chen. Liang Chen. Zhaoyu Chen. Kwongsang Cheng. Lang Cui. Benzhong Dai. Zhen Ding. Dimitrios Emmanoulopoulos. Xiaohong Fan. Junhui Fan. Longxing Fan.

  20. Microwave-assisted modulated synthesis of zirconium-based metal–organic framework (Zr-MOF) for hydrogen storage applications

    CSIR Research Space (South Africa)

    Ren, Jianwei

    2014-05-01

    Full Text Available .1002/chem.200903526 [2] H. Wu, Y.S. Chua, V. Krungleviciute, M. Tyagi, P. Chen, T. Yil- dirim, W. Zhou: J. Am. Chem. Soc. 135 (2013) 10525. DOI:10.1021/ja404514r [3] Q.Y. Yang, A.D. Wiersum, P.L. Llewellyn, V. Guillerm, C. Serre, G. Maurin: Chem. Commun. 47... (2011) 9603. DOI:10.1039/C1CC13543 K [4] J.H. Cavka, S. Jakobsen, U. Olsbye, N. Guillou, C. Lamberti, S. Bordiga, K.P. Lillerud: J. Am. Chem. Soc. 130 (2008) 13850. DOI:10.1021/ja8057953 [5] T. Tsuruoka, S. Furukawa, Y. Takashima, K. Yoshida, S. Isoda, S...

  1. Information systems and computing technology

    CERN Document Server

    Zhang, Lei

    2013-01-01

    Invited papersIncorporating the multi-cross-sectional temporal effect in Geographically Weighted Logit Regression K. Wu, B. Liu, B. Huang & Z. LeiOne shot learning human actions recognition using key posesW.H. Zou, S.G. Li, Z. Lei & N. DaiBand grouping pansharpening for WorldView-2 satellite images X. LiResearch on GIS based haze trajectory data analysis system Y. Wang, J. Chen, J. Shu & X. WangRegular papersA warning model of systemic financial risks W. Xu & Q. WangResearch on smart mobile phone user experience with grounded theory J.P. Wan & Y.H. ZhuThe software reliability analysis based on

  2. Almost Periodic Dynamics for Memristor-Based Shunting Inhibitory Cellular Neural Networks with Leakage Delays

    Directory of Open Access Journals (Sweden)

    Lin Lu

    2016-01-01

    Full Text Available We investigate a class of memristor-based shunting inhibitory cellular neural networks with leakage delays. By applying a new Lyapunov function method, we prove that the neural network which has a unique almost periodic solution is globally exponentially stable. Moreover, the theoretical findings of this paper on the almost periodic solution are applied to prove the existence and stability of periodic solution for memristor-based shunting inhibitory cellular neural networks with leakage delays and periodic coefficients. An example is given to illustrate the effectiveness of the theoretical results. The results obtained in this paper are completely new and complement the previously known studies of Wu (2011 and Chen and Cao (2002.

  3. Dating young tephras - a distal solution to proximal controversy

    Science.gov (United States)

    Chen, Xuanyu; Blockley, Simon; Xu, Yigang; Menzies, Martin

    2017-04-01

    In-situ dating of young volcanic rocks (Science, 291(5508): 1497-1499. Chen, X.-Y., Blockley, S.P.E., Tarasov, P.E., Xu, Y.-G., McLean, D., Tomlinson, E.L., Albert, P.G., Liu, J.-Q., Müller, S., Wagner, M. and Menzies, M.A., 2016. Clarifying the distal to proximal tephrochronology of the Millennium (B-Tm) eruption, Changbaishan Volcano, northeast China. Quat. Geochronol., 33: 61-75. Ge, Q. and Wu, W., 2011. Climate during the Medieval Climate Anomaly in China. PAGES news, 19: 24-26. Sun, C., Plunkett, G., Liu, J., Zhao, H., Sigl, M., McConnell, J.R., Pilcher, J.R., Vinther, B., Steffensen, J.P. and Hall, V., 2014. Ash from Changbaishan Millennium eruption recorded in Greenland ice: Implications for determining the eruption's timing and impact. Geophys. Res. Lett., 2013GL058642.

  4. Development of acquired factor V inhibitor after treatment with ceftazidime: a case report and review of the literature

    Directory of Open Access Journals (Sweden)

    Cui QY

    2015-04-01

    Full Text Available Qing-ya Cui,1 Hong-shi Shen,1 Tian-qin Wu,1 Hai-fei Chen,1 Zi-qiang Yu,2 Zhao-yue Wang2 1Department of Hematology, PLA 100th Hospital, 2Jiangsu Institute of Hematology, The First Affiliated Hospital of Soochow University, Suzhou, People’s Republic of China Abstract: We report the case of a 59-year-old Chinese man who showed an asymptomatic coagulation factor V deficiency pattern after second intravenous treatment with ceftazidime. Normal pooled plasma failed to correct the abnormalities in a mixing test, and the presence of factor V inhibitor was confirmed by the Bethesda method. The coagulopathy was not corrected by transfusion of fresh frozen plasma and prothrombin complex concentrate, but rather by treatment with prednisone and withdrawal of dubious drugs. The findings reported here should prompt clinicians to watch for drug-induced coagulation factor deficiency. Keywords: acquired factor V deficiency, coagulopathy, prednisone

  5. The Chinese Path to Modernisation. Discussions of “Culture” and “Morality” in Republican China

    Directory of Open Access Journals (Sweden)

    Tze-ki Hon

    2014-12-01

    Full Text Available In this paper, I will examine the notion of “alternative modernity” that was prominent during Republican China. In the first section, I will discuss “the debate on science and the philosophy of life” (1923 and the debate over total westernisation (1935, highlighting the two main areas of contention between the May Fourth intellectuals and their critics: scientism and populism. In the second section, I will compare the writings of four thinkers: Liang Shuming (1893-1988, Wu Mei (1894-1978, Liu Yizheng (1880-1956, and Chen Yinke (1890-1969, focusing on how they used “culture” (wenhua and “morality” (daode to chart a Chinese path to modernisation. In the third section, I will discuss the reasons for a lack of support for alternative modernity in Republican China.

  6. Reinfusion of ascites during hemodialysis as a treatment of massive refractory ascites and acute renal failure

    Directory of Open Access Journals (Sweden)

    Ta-Wei Hsu

    2011-02-01

    Full Text Available Ta-Wei Hsu1, Yi-Chuan Chen2, Meei-Ju Wu2, Anna Fen-Yau Li3, Wu-Chang Yang2, Yee-Yung Ng21Department of Medicine, I-Lan Hospital, 2Division of Nephrology, Department of Medicine, 3Department of Pathology, Taipei Veterans General Hospital, School of Medicine, National Yang-Ming University, Taipei, TaiwanAbstract: Refractory ascites can occur in patients with various conditions. Although several procedures based on the reinfusion of ascitic fluid have been reported after the failure of bed rest, salt and water restriction, diuretics, intravenous administration of albumin, and repeated paracentesis, these procedures are performed for ascitic fluid removal without dialytic effect. In this study, a flow control reinfusion of ascites during hemodialysis (HD was performed to demonstrate the efficacy of this method in a lupus patient with massive refractory ascites and respiratory and acute renal failure (ARF. The alleviation of ascites and ARF attests to the success of the flow control reinfusion of ascites during HD. This procedure can control the rate of ascites and body fluid removal simultaneously during HD using the roller pump. In conclusion, with a normal coagulation profile, the procedure of flow control reinfusion of ascites during HD is an effective alternative treatment for the alleviation of refractory ascites with renal failure.Keywords: ascites, lupus, renal failure, reinfusion

  7. Dissolving and biodegradable microneedle technologies for transdermal sustained delivery of drug and vaccine

    Directory of Open Access Journals (Sweden)

    Hong X

    2013-09-01

    Full Text Available Xiaoyun Hong,1,2,* Liangming Wei,3,* Fei Wu,2,* Zaozhan Wu,2 Lizhu Chen,2 Zhenguo Liu,1 Weien Yuan2 1Department of Neurology, Xinhua Hospital, Shanghai, People's Republic of China; 2School of Pharmacy, Shanghai JiaoTong University, Shanghai, People's Republic of China; 3Research Institute of Micro/Nano Science and Technology, Shanghai JiaoTong University, Shanghai, People's Republic of China *These authors contributed equally to this work Abstract: Microneedles were first conceptualized for drug delivery many decades ago, overcoming the shortages and preserving the advantages of hypodermic needle and conventional transdermal drug-delivery systems to some extent. Dissolving and biodegradable microneedle technologies have been used for transdermal sustained deliveries of different drugs and vaccines. This review describes microneedle geometry and the representative dissolving and biodegradable microneedle delivery methods via the skin, followed by the fabricating methods. Finally, this review puts forward some perspectives that require further investigation. Keywords: microneedle, dissolving, biodegradable, sustained release

  8. Some additional considerations in modelling the dynamic traits and genome-wide association studies. Comments on "Mapping complex traits as a dynamic system" by L. Sun and R. Wu

    Science.gov (United States)

    Das, Kiranmoy

    2015-06-01

    The revolution in the genetic research in our time is mainly due to (i) the successful completion of human genome project (2003) and its derivative hapmap project (2005), (ii) advanced statistical methodologies for analyzing ultrahigh dimensional data and (iii) the availability of statistical softwares (R, SAS etc.) to analyze large datasets. When complex traits are to be modeled as dynamic systems, the statistical issues regarding the complexity in the model, predictive power of the model, computational cost etc. are to be addressed adequately for powerful inferences. I will mention two additional considerations (statistical) which make dynamic models more meaningful and the results from GWAS more reliable.

  9. Analisis harf واو العاملة /wāwu al-‘āmilah/ dalam Al-Qur`an Juz 30

    OpenAIRE

    Fatahillah, Muhammad

    2012-01-01

    و اسباب احتيار هذا الموضوع لأن حرف واو العاملة في جزء ثلاثين من القران لها انواع و عامل و اعراب مختلفة عند اتصل باية . و اما الغرض الأقصى من هذا البحث هي لتعريف نوع و عامل و اعراب حرف واو العاملة في جزء ثلاثين من القران. , فا الكاتب يستعمل نظرية ما تقدمها شيخ "غلايينى" في كتابه "جامع الدروس العربية" فاما هذا البحث هي الدراسية المكتبية التي تستعمل طريقة الإستنتاجية. و الحاصلات من هذا البحث ان عدد حرف واو العاملة في جزء ثلاثين من القران ١٧٨حرفا, منها ١١ حرف واو قسم الذ...

  10. Parental Choice of School, Class Strategies, and Educational Inequality: An Essay Review of "School Choice in China--A Different Tale?" (X. Wu, New York, NY: Routledge, 2014, 168 pp. ISBN 978-0-415-81769-1)

    Science.gov (United States)

    Liu, Shuning; Apple, Michael W.

    2016-01-01

    Given the increasingly global nature of marketized school choice policies, this makes it even more crucial to investigate how the multiple scales, forms, and emphases of school choice in different countries are influenced by particular political, economic, and cultural conditions. While much of the critical research on school choice policies has…

  11. The 2nd International Conference on Water Resource and Environment (WRE 2016

    Directory of Open Access Journals (Sweden)

    Zhouli Liu

    2016-11-01

    Full Text Available Table of contents 01 The eco-toxicological effects of cadmium stress on five ornamental plants Zhouli Liu, Wei Chen, Xingyuan He, Shuai Yu, Weihang Ding 02 Study on the formation and release mechanisms of hydrogen sulfide in Longtan coal mine Jianjun Liu, Yuliang Wu, Kaixiang Fan 03 Coral bleaching in the North Reef of China’s Xisha Islands in 2014 Yuanchao Li, Xinqing Zheng, Shiquan Chen, Haiqun Xie 04 Soil chemical characteristics in a Cunninghamia lanceolata stand suffering from ice-snow damage Jie Li, Zhuomin Wang, Li Xue 05 Diversity of understory vegetation was under a Cunninghamia lanceolata stand suffering from ice-snow damage Zhiyang Lie, Weilong Huang, Tongtong Zhou, Li Xue 06 The effect of water, nitrogen and harvesting time on yield and biomass allocation of Helianthus tuberosus L. Kai Gao, Tiexia Zhu 07 The vertical variation of microbial communities in the sediment of sea cucumber pond Weiteng Mao, Pei Yu, Xinfang Lv, Yunchun Li 08 Indicating significances of alpine plant functional groups to environmental change Peixi Su, Rui Shi 09 Research on the daily CH4 fluxes of soil in summer mangrove community at Yingluogang of Guangxi, China Yong Jiang, Xingbin Chen, Shichu liang 10 Beach protection structures in middle and lower reaches of Yangtze River Junfeng Xu 11 Social responsibility management of large dam project with owner as core: an empirical case in China Jiwei Zhu, Zhao Zhai, Linan Zhou, Yun Le, Li Cao 12 The ecological function value assessment analysis of urban waterfront Jiwei Zhu, Ping Lu, Zhiqian Huang, Bei Zhou 13 Mechanism of diurnal osmotic potential changes and adjustment of three Caragana species in different habitats of the Inner Mongolia Plateau Zhirong Zheng, Shihai Lv, Chaoyang Feng 14 Biodiversity of phytoplankton and environmental influences analysis of Longfeng Wetland, China Nan Song, Yan Liu, Xinxin Lu, Yawen Fan 15 The effect of human activities on culturable soil microbes from Yaoquan Mountain in

  12. Indole and synthetic derivative activate chaperone expression to reduce polyQ aggregation in SCA17 neuronal cell and slice culture models

    Directory of Open Access Journals (Sweden)

    Kung PJ

    2014-10-01

    Full Text Available Pin-Jui Kung,1,* Yu-Chen Tao,1,* Ho-Chiang Hsu,1 Wan-Ling Chen,1 Te-Hsien Lin,1 Donala Janreddy,2 Ching-Fa Yao,2 Kuo-Hsuan Chang,3 Jung-Yaw Lin,1 Ming-Tsan Su,1 Chung-Hsin Wu,1 Guey-Jen Lee-Chen,1 Hsiu-Mei Hsieh-Li1 1Department of Life Science, 2Department of Chemistry, National Taiwan Normal University, Taipei, Taiwan; 3Department of Neurology, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Taipei, Taiwan *These authors contributed equally to this work Abstract: In spinocerebellar ataxia type 17 (SCA17, the expansion of a translated CAG repeat in the TATA box binding protein (TBP gene results in a long polyglutamine (polyQ tract in the TBP protein, leading to intracellular accumulation of aggregated TBP and cell death. The molecular chaperones act in preventing protein aggregation to ameliorate downstream harmful events. In this study, we used Tet-On SH-SY5Y cells with inducible SCA17 TBP/Q79-green fluorescent protein (GFP expression to test indole and synthetic derivative NC001-8 for neuroprotection. We found that indole and NC001-8 up-regulated chaperone expression to reduce polyQ aggregation in neuronal differentiated TBP/Q79 cells. The effects on promoting neurite outgrowth and on reduction of aggregation on Purkinje cells were also confirmed with cerebellar primary and slice cultures of SCA17 transgenic mice. Our results demonstrate how indole and derivative NC001-8 reduce polyQ aggregation to support their therapeutic potentials in SCA17 treatment. Keywords: spinocerebellar ataxia type 17, TATA box binding protein, polyQ aggregation, indole and derivative, therapeutics

  13. Regular-, irregular-, and pseudo-character processing in Chinese: The regularity effect in normal adult readers

    Directory of Open Access Journals (Sweden)

    Dustin Kai Yan Lau

    2014-03-01

    Full Text Available Background Unlike alphabetic languages, Chinese uses a logographic script. However, the pronunciation of many character’s phonetic radical has the same pronunciation as the character as a whole. These are considered regular characters and can be read through a lexical non-semantic route (Weekes & Chen, 1999. Pseudocharacters are another way to study this non-semantic route. A pseudocharacter is the combination of existing semantic and phonetic radicals in their legal positions resulting in a non-existing character (Ho, Chan, Chung, Lee, & Tsang, 2007. Pseudocharacters can be pronounced by direct derivation from the sound of its phonetic radical. Conversely, if the pronunciation of a character does not follow that of the phonetic radical, it is considered as irregular and can only be correctly read through the lexical-semantic route. The aim of the current investigation was to examine reading aloud in normal adults. We hypothesized that the regularity effect, previously described for alphabetical scripts and acquired dyslexic patients of Chinese (Weekes & Chen, 1999; Wu, Liu, Sun, Chromik, & Zhang, 2014, would also be present in normal adult Chinese readers. Method Participants. Thirty (50% female native Hong Kong Cantonese speakers with a mean age of 19.6 years and a mean education of 12.9 years. Stimuli. Sixty regular-, 60 irregular-, and 60 pseudo-characters (with at least 75% of name agreement in Chinese were matched by initial phoneme, number of strokes and family size. Additionally, regular- and irregular-characters were matched by frequency (low and consistency. Procedure. Each participant was asked to read aloud the stimuli presented on a laptop using the DMDX software. The order of stimuli presentation was randomized. Data analysis. ANOVAs were carried out by participants and items with RTs and errors as dependent variables and type of stimuli (regular-, irregular- and pseudo-character as repeated measures (F1 or between subject

  14. systems, pelagic fish of the southern Benguela are dominated

    African Journals Online (AJOL)

    denise

    diatom carbon and nitrogen efficiently (van der Lingen. 1998a). Field studies in the southern Benguela have ... cyclopoid copepods, calanoid copepods and diatoms. Virtually all prey items ingested by sardine were ... Sardine were collected during research cruises under- taken in October and November 1992, November ...

  15. Forbrydelse betaler sig i Danmark

    DEFF Research Database (Denmark)

    Svendsen, Gert Tinggaard

    1998-01-01

    Forbrydelse straffes ikke nævneværdigt i Danmark, så hvorfor skal politiet fange forbryderne? Naturligvis skal strafudmålingen understøtte den almindelige moral, så enhver potentiel forbryder end ikke overvejer, om det kan betale sig at begå kriminalitet. Hvorfor griber politikerne ikke effektivt...

  16. Solar heating in Greenland

    DEFF Research Database (Denmark)

    Dragsted, Janne

    Energi fra solen er en ren og naturlig energikilde. Solstrålingen på jordens overflade – inklusive i det Arktiske klima – er så stor, at det er muligt at udnytte solens energi i stor skala. Ved at udnytte solens energi nedsættes brugen af fossile brændstoffer. Anvendelsen af solenergi varierer fr...

  17. 2017-12-08T08:29:22Z https://www.ajol.info/index.php/all/oai oai:ojs ...

    African Journals Online (AJOL)

    article/33520 2011-10-02T09:11:45Z ajms:ART Fine-scale spatial variability of ... L; Institut de Recherche pour le Développement, 213 rue Lafayette, 75480 Paris, France van der Lingen, CD; Marine and Coastal Management, Department of ...

  18. Improving evaluation criteria for monitoring networks of weak radioactive plumes after nuclear emergencies

    DEFF Research Database (Denmark)

    Urso, L.; Astrup, Poul; Helle, K.B.

    2012-01-01

    and efficiency of sections of these networks. As a test case the existing sampling design of the Dutch and German networks with 193 sensors in an area of 200 km around the nuclear power plant near the city of Lingen (Emsland) in the German federal state of Lower Saxony has been selected. For a hypothetical...

  19. Traditional Chinese Medicine Induced Liver Injury.

    Science.gov (United States)

    Teschke, Rolf

    2014-06-01

    Traditional Chinese Medicine (TCM) is popular around the world and encompasses many different practices with particular emphasis on herbal TCM. Using the PubMed database, a literature search was undertaken to assess the extent herbal TCM products exert rare hepatotoxicity. Analysis of reported cases revealed numerous specified herbal TCM products with potential hepatotoxicity. Among these were An Shu Ling, Bai Fang, Bai Xian Pi, Ban Tu Wan, Bo He, Bo Ye Qing Niu Dan, Bofu Tsu Sho San, Boh Gol Zhee, Cang Er Zi, Chai Hu, Chaso, Chi R Yun, Chuan Lian Zi, Ci Wu Jia, Da Chai Hu Tang, Da Huang, Du Huo, Gan Cao, Ge Gen, Ho Shou Wu, Hu Bohe You, Hu Zhang, Huang Qin, Huang Yao Zi, Hwang Geun Cho, Ji Gu Cao, Ji Ji, Ji Xue Cao, Jiguja, Jin Bu Huan, Jue Ming Zi, Kamishoyosan, Kudzu, Lei Gong Teng, Long Dan Xie Gan Tang, Lu Cha, Ma Huang, Mao Guo Tian Jie Cai, Onshido, Polygonum multiflorum, Qian Li Guang, Ren Shen, Sairei To, Shan Chi, Shen Min, Shi Can, Shi Liu Pi, Shou Wu Pian, Tian Hua Fen, White flood, Wu Bei Zi, Xi Shu, Xiao Chai Hu Tang, Yin Chen Hao, Zexie, Zhen Chu Cao, and various unclassified Chinese herbal mixtures. Causality was firmly established for a number of herbal TCM products by a positive reexposure test result, the liver specific scale of CIOMS (Council for International Organizations of Medical Sciences), or both. Otherwise, the quality of case data was mixed, especially regarding analysis of the herb ingredients because of adulteration with synthetic drugs, contamination with heavy metals, and misidentification. In addition, non-herbal TCM elements derived from Agaricus blazei, Agkistrodon, Antelope, Bombyx, Carp, Fish gallbladder, Phellinus, Scolopendra, Scorpio, and Zaocys are also known or potential hepatotoxins. For some patients, the clinical course was severe, with risks for acute liver failure, liver transplantation requirement, and lethality. In conclusion, the use of few herbal TCM products may rarely be associated with hepatotoxicity in some

  20. Traditional Chinese Medicine Induced Liver Injury

    Science.gov (United States)

    2014-01-01

    Traditional Chinese Medicine (TCM) is popular around the world and encompasses many different practices with particular emphasis on herbal TCM. Using the PubMed database, a literature search was undertaken to assess the extent herbal TCM products exert rare hepatotoxicity. Analysis of reported cases revealed numerous specified herbal TCM products with potential hepatotoxicity. Among these were An Shu Ling, Bai Fang, Bai Xian Pi, Ban Tu Wan, Bo He, Bo Ye Qing Niu Dan, Bofu Tsu Sho San, Boh Gol Zhee, Cang Er Zi, Chai Hu, Chaso, Chi R Yun, Chuan Lian Zi, Ci Wu Jia, Da Chai Hu Tang, Da Huang, Du Huo, Gan Cao, Ge Gen, Ho Shou Wu, Hu Bohe You, Hu Zhang, Huang Qin, Huang Yao Zi, Hwang Geun Cho, Ji Gu Cao, Ji Ji, Ji Xue Cao, Jiguja, Jin Bu Huan, Jue Ming Zi, Kamishoyosan, Kudzu, Lei Gong Teng, Long Dan Xie Gan Tang, Lu Cha, Ma Huang, Mao Guo Tian Jie Cai, Onshido, Polygonum multiflorum, Qian Li Guang, Ren Shen, Sairei To, Shan Chi, Shen Min, Shi Can, Shi Liu Pi, Shou Wu Pian, Tian Hua Fen, White flood, Wu Bei Zi, Xi Shu, Xiao Chai Hu Tang, Yin Chen Hao, Zexie, Zhen Chu Cao, and various unclassified Chinese herbal mixtures. Causality was firmly established for a number of herbal TCM products by a positive reexposure test result, the liver specific scale of CIOMS (Council for International Organizations of Medical Sciences), or both. Otherwise, the quality of case data was mixed, especially regarding analysis of the herb ingredients because of adulteration with synthetic drugs, contamination with heavy metals, and misidentification. In addition, non-herbal TCM elements derived from Agaricus blazei, Agkistrodon, Antelope, Bombyx, Carp, Fish gallbladder, Phellinus, Scolopendra, Scorpio, and Zaocys are also known or potential hepatotoxins. For some patients, the clinical course was severe, with risks for acute liver failure, liver transplantation requirement, and lethality. In conclusion, the use of few herbal TCM products may rarely be associated with hepatotoxicity in some

  1. The aqueous extract of Glycyrrhiza inflata can upregulate unfolded protein response-mediated chaperones to reduce tau misfolding in cell models of Alzheimer’s disease

    Directory of Open Access Journals (Sweden)

    Chang KH

    2016-02-01

    Full Text Available Kuo-Hsuan Chang,1,* I-Cheng Chen,1,* Hsuan-Yuan Lin,2 Hsuan-Chiang Chen,2 Chih-Hsin Lin,1 Te-Hsien Lin,2 Yu-Ting Weng,1 Chih-Ying Chao,1 Yih-Ru Wu,1 Jung-Yaw Lin,2 Guey-Jen Lee-Chen,2 Chiung-Mei Chen1 1Department of Neurology, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, 2Department of Life Science, National Taiwan Normal University, Taipei, Taiwan, Republic of China *These authors contributed equally to this work Background: Alzheimer’s disease (AD and several neurodegenerative disorders known as tauopathies are characterized by misfolding and aggregation of tau protein. Although several studies have suggested the potential of traditional Chinese medicine (TCM as treatment for neurodegenerative diseases, the role of TCM in treating AD and tauopathies have not been well explored.Materials and methods: Tau protein was coupled to the DsRed fluorophore by fusing a pro-aggregation mutant of repeat domain of tau (ΔK280 tauRD with DsRed. The ΔK280 tauRD-DsRed fusion gene was then used to generate Tet-On 293 and SH-SY5Y cell clones as platforms to test the efficacy of 39 aqueous extracts of TCM in reducing tau misfolding and in neuroprotection.Results: Seven TCM extracts demonstrated a significant reduction in tau misfolding and reactive oxidative species with low cytotoxicity in the ΔK280 tauRD-DsRed 293 cell model. Glycyrrhiza inflata and Panax ginseng also demonstrated the potential to improve neurite outgrowth in the ΔK280 tauRD-DsRed SH-SY5Y neuronal cell model. G. inflata further rescued the upregulation of ERN2 (pro-apoptotic and downregulation of unfolded-protein-response-mediated chaperones ERP44, DNAJC3, and SERP1 in ΔK280 tauRD-DsRed 293 cells.Conclusion: This in vitro study provides evidence that G. inflata may be a novel therapeutic for AD and tauopathies. Future applications of G. inflata on animal models of AD and tauopathies are warranted to corroborate its effect of reducing misfolding and potential

  2. Ultrasonic evaluation of central retinal artery hemodynamics in patients with hypertensive disorder complicating pregnancy and the correlation with diseaseChen-Xia Liu, Jing-Mian Zhou

    Directory of Open Access Journals (Sweden)

    Chen-Xia Liu

    2017-01-01

    Full Text Available Objective: To study the correlation between central retinal artery hemodynamic characteristics in patients with hypertensive disorder complicating pregnancy and endothelial injury molecules as well as trophoblast cell apoptosis molecules. Methods: 45 healthy pregnant women, 37 patients with gestational hypertension and 24 patients with preeclampsia who gave birth in Obstetrics Department of our hospital between May 2013 and December 2015 were selected and included in the control group, GH group and PE group respectively. Central retinal artery ultrasonography was done to determine peak systolic velocity (PSV, end-diastolic velocity (EDV and resistance index (RI, serum was collected to determine interleukin-6 (IL-6, IL- 17, IL-24, chemokine ligand 10 (CXCL10 and cartilage glycoprotein 40 (YKL40 content, and placenta tissue was collected to determine Fas, FasL, Bax, Caspase-3, Caspase-9, XIAP, Survivin and Livin expression. Results: Central retinal artery PSV and EDV as well as XIAP, Survivin and Livin expression in placenta of GH group and PE group were significantly lower than those of control group (P<0.05 while central retinal artery RI, serum IL-6, IL- 17, IL-24, CXCL10 and YKL40 content as well as Fas, FasL, Bax, Caspase-3 and Caspase-9 expression in placenta were significantly higher than those of control group (P<0.05. Central retinal artery PSV and EDV as well as XIAP, Survivin and Livin expression in placenta of PE group were significantly lower than those of GH group (P<0.05 while central retinal artery RI, serum IL-6, IL-17, IL-24, CXCL10 and YKL40 content as well as Fas, FasL, Bax, Caspase-3 and Caspase-9 expression in placenta were significantly higher than those of GH group (P<0.05. Serum IL-6, IL-17, IL-24, CXCL10 and YKL40 content as well as Fas, FasL, Bax, Caspase-3 and Caspase-9 expression in placenta were negatively correlated with PSV and EDV, and positively correlated with RI; XIAP, Survivin and Livin expression in placenta were positively correlated with PSV and EDV, and negatively correlated with RI. Conclusions: Central retinal artery blood flow characteristics in patients with hypertensive disorder complicating pregnancy are the significantly increased blood flow resistance and the significantly decreased blood flow volume, and the above blood flow characteristics are associated with maternal endothelial injury and trophoblast cell apoptosis.

  3. Monitoring Protein Conformation Changes as an Activating Step for Protein Interactions with Cross-linking/MS Analysis. / Chen, Zhuo; Rasmussen, Morten; Tahir, Salman; Clark, C.A.C; Barlow, Paul; Rappsilber, Juri

    DEFF Research Database (Denmark)

    Rasmussen, Morten

    -linked peptides have been enriched with SCX-StageTips. High resolution MS/MS spectra were acquired on an LTQ-Orbitrap mass spectrometer coupled online to a nanoHPLC. Singly and doubly charged ions were rejected for fragmentation. Peak lists were generated with MaxQuant. The database searches for cross......, the cross-link data and the crystal structure can be harmonized. We suggest that cross-linking can capture aspects of protein dynamics in solution that are not observable in static crystal structures....

  4. (Asian) Life (in Asia) - Book reviews of Margaret Sleeboom-Faulkner (Ed.): Frameworks of Choice, Amsterdam, Amsterdam Press 2010 and Aihwa Ong & Nancy Chen: Asian Biotech, Durham & London, Duke University Press 2010

    DEFF Research Database (Denmark)

    Wahlberg, Ayo

    2011-01-01

    This article is concerned with the idea of societal 'spaciousness' and its relationship to individual and collective autonomy. These issues are analyzed in the context of the eviction of a self-managed social center of left-radical activists in Copenhagen and the protests and public debate...

  5. (Asian) Life (in Asia) - Book reviews of Margaret Sleeboom-Faulkner (Ed.): Frameworks of Choice, Amsterdam, Amsterdam Press 2010 and Aihwa Ong & Nancy Chen: Asian Biotech, Durham & London, Duke University Press 2010

    DEFF Research Database (Denmark)

    Wahlberg, Ayo

    2011-01-01

    This article is concerned with the idea of societal 'spaciousness' and its relationship to individual and collective autonomy. These issues are analyzed in the context of the eviction of a self-managed social center of left-radical activists in Copenhagen and the protests and public debate...... that followed. The authors find that societal spaciousness in Denmark is metaphorically associated with a house or a limited physical space. People should limit themselves in public space, as in a house, to 'make room' for all. Because youngsters are not conceived of as fully fledged political subjects who...

  6. Impact of lymphovascular invasion on recurrence and progression rates in patients with pT1 urothelial carcinoma of bladder after transurethral resection

    Directory of Open Access Journals (Sweden)

    Sha N

    2015-11-01

    Full Text Available Nan Sha,* Linguo Xie,* Tao Chen,* Chen Xing, Xiaoteng Liu, Yu Zhang, Zhonghua Shen, Hao Xu, Zhouliang Wu, Hailong Hu, Changli Wu Department of Urology, Tianjin Key Laboratory of Urology, Tianjin Institute of Urology, Second Hospital of Tianjin Medical University, Tianjin, People’s Republic of China *These authors contributed equally to this work Objective: To evaluate the clinical significance of lymphovascular invasion (LVI on recurrence and progression rates in patients with pT1 urothelial carcinoma of bladder after transurethral resection.Methods: This retrospective study was performed with 155 patients with newly diagnosed pT1 urothelial carcinoma of bladder who were treated with transurethral resection of bladder tumor at our institution from January 2006 to January 2010. The presence or absence of LVI was examined by pathologists. Chi-square test was performed to identify the correlations between LVI and other clinical and pathological features. Kaplan–Meier method was used to estimate the recurrence-free survival (RFS and progression-free survival curves and difference was determined by the log-rank test. Univariate and multivariate analyses were performed to determine the predictive factors through a Cox proportional hazards analysis model.Results: LVI was detected in a total of 34 patients (21.9%. While LVI was associated with high-grade tumors (P<0.001 and intravesical therapy (P=0.009. Correlations with age (P=0.227, sex (P=0.376, tumor size (P=0.969, tumor multiplicity (P=0.196, carcinoma in situ (P=0.321, and smoking (P=0.438 were not statistically significant. There was a statistically significant tendency toward higher recurrence rate and shorter RFS time in LVI-positive patients. However, no statistically significant differences were observed in progression rate between the two groups. Moreover, multivariate Cox proportional hazards analysis revealed that LVI, tumor size, and smoking were independent prognostic predictors of

  7. AcEST: BP915174 [AcEST

    Lifescience Database Archive (English)

    Full Text Available >tr|A8WU00|A8WU00_CAEBR CBR-ABTS-3 protein OS=Caenorhabditis briggsae GN=Cbr-abts-3 PE=4 SV=2 Length = 1016 ...sis protein OS=B... 33 9.1 tr|A8WU00|A8WU00_CAEBR CBR-ABTS-3 protein OS=Caenorhab

  8. Proceedings of the 2016 China Cancer Immunotherapy Workshop

    Directory of Open Access Journals (Sweden)

    Bin Xue

    2016-10-01

    Full Text Available Table of contents A1 Proceedings of 2016 China Cancer Immunotherapy Workshop, Beijing, China Bin Xue, Jiaqi Xu, Wenru Song, Zhimin Yang, Ke Liu, Zihai Li A2 Set the stage: fundamental immunology in forty minutes Zihai Li A3 What have we learnt from the anti-PD-1/PD-L1 therapy of advanced human cancer? Lieping Chen A4 Immune checkpoint inhibitors in lung cancer Edward B. Garon A5 Mechanisms of response and resistance to checkpoint inhibitors in melanoma Siwen Hu-Lieskovan A6 Checkpoint inhibitor immunotherapy in lymphoid malignancies Wei Ding A7 Translational research to improve the efficacy of immunotherapy in genitourinary malignancies Chong-Xian Pan A8 Immune checkpoint inhibitors in gastrointestinal malignancies Weijing Sun A9 What’s next beyond PD-1/PDL1? Yong-Jun Liu A10 Cancer vaccines: new insights into the oldest immunotherapy strategy Lei Zheng A11 Bispecific antibodies for cancer immunotherapy Delong Liu A12 Updates on CAR-T immunotherapy Michel Sadelain A13 Adoptive T cell therapy: personalizing cancer treatment Cassian Yee A14 Immune targets and neoantigens for cancer immunotherapy Rongfu Wang A15 Phase I/IIa trial of chimeric antigen receptor modified T cells against CD133 in patients with advanced and metastatic solid tumors Meixia Chen, Yao Wang, Zhiqiang Wu, Hanren Dai, Can Luo, Yang Liu, Chuan Tong, Yelei Guo, Qingming Yang, Weidong Han A16 Cancer immunotherapy biomarkers: progress and issues Lisa H. Butterfield A17 Shaping of immunotherapy response by cancer genomes Timothy A. Chan A18 Unique development consideration for cancer immunotherapy Wenru Song A19 Immunotherapy combination Ruirong Yuan A20 Immunotherapy combination with radiotherapy Bo Lu A21 Cancer immunotherapy: past, present and future Ke Liu A22 Breakthrough therapy designation drug development and approval Max Ning A23 Current European regulation of innovative oncology medicines: opportunities for immunotherapy Harald Enzmann, Heinz Zwierzina

  9. The role of hSCs in promoting neural differentiation of hUC-MSCs in spinal cord injury

    Directory of Open Access Journals (Sweden)

    Wu QL

    2013-11-01

    Full Text Available Qiuli Wu,1,* You Chen,1,* Guangzhi Ning,1 Shiqing Feng,1 Junling Han,2 Qiang Wu,1 Yulin LI,1 Hong Wu,1 Hongyu Shi1 1Department of Orthopedics, Tianjin Medical University General Hospital, Tianjin, People's Republic of China; 2Tianjin Union Stem Cell and Gene Engineering Co., Ltd, Tianjin, People's Republic of China * These authors contributed equally to this paper Abstract: Cell therapy is a promising approach to treating spinal cord injury (SCI. Previous studies demonstrated that co-transplantation of human umbilical cord mesenchymal stem cells (hUC-MSCs and human Schwann cells (hSCs was an effective strategy by which to promote the regeneration of corticospinal fibers and locomotor recovery after SCI in rats. However, the neural differentiation potential of hUC-MSCs was not fully understood. In the present study, we examined the influence of hSCs on the survival and differentiation of hUC-MSCs in SCI rats. Four groups of rats were implanted with Dulbecco's Modified Eagle's Medium (DMEM, hSCs, hUC-MSCs, or a combination of hSCs and hUC-MSCs, respectively. Our results demonstrated that MAB1281 immunopositive cells appeared in the injured site of the transplanted cell groups, while myelin basic protein and high-molecular-weight neurofilament immunopositive cells were detected only in the co-transplantation group under the positive background of MAB1281. Furthermore, polymerase chain reaction (PCR and Western blot showed significantly higher expression of myelin basic protein and high-molecular-weight neurofilament and lower expression of glial fibrillary acidic protein in the co-transplantation group (P < 0.05, which correlated strongly with immunofluorescence findings. These results suggest that hSCs could induce hUC-MSC differentiation into neurons and oligodendrocytes and inhibit the formation of glial scarring after SCI. The neural differentiation of hUC-MSCs is likely induced by soluble factors provided by hSCs. Keywords: spinal cord injury

  10. Status and perspectives of the dismantling of nuclear power plants in Germany (Dismantling monitoring 2015); Stand und Perspektiven des Rueckbaus von Kernkraftwerken in Deutschland (''Rueckbau-Monitoring 2015'')

    Energy Technology Data Exchange (ETDEWEB)

    Wealer, Ben; Seidel, Jan Paul [Technische Univ. Berlin (Germany); Gerbaulet, Clemens; Hirschhausen, Christian von [Technische Univ. Berlin (Germany); Deutsches Institut fuer Wirtschaftsforschung, Berlin (Germany)

    2015-11-15

    The dismantling monitoring 2015 covers the nuclear power plants HDR Grosswelzheim, Niederaichbach (KKN), MZFR Karlsruhe, Lingen (KWL), Gundremmingen unit A (KRB-A), VAK Kahl, Muehlheim-Kaerlich (KMK), THTR-300 Hamm-Uentrop, AVR Juelich, Greifswald (KGR 1-5), KNK II Karlsruhe, Rheinsberg (KKR), Wuergassen (KWW), Stade (KKS), Obrigheim (KWO), SNR 300. The post-operational phase activities of other shut-down nuclear power plants and the active companies are summarized.

  11. Effektmåling af ”Sikker Trafik Live” – delrapport 1

    DEFF Research Database (Denmark)

    Hansen, Helle; Sandoy, Tróndur Møller; Kristensen, Christian Li

    at deltage i undersøgelsen og herefter randomiseret til at få besøg af en LIVE-ambassadør enten i efteråret 2016 eller i foråret 2017. Data er indsamlet via et elektronisk spørgeskema i perioden august-september 2016 og igen i januar 2017, inden kontrolgruppen fik deres LIVE-besøg. Målingen er bygget op...

  12. Organic food conversion in Danish public kitchens

    DEFF Research Database (Denmark)

    Sørensen, Nina Nørgaard

    slutmålinger af den psykiske arbejdstrivsel blandt køkkenmedarbejderne og kun en enkelt signifikant forskel i målingerne af fysisk arbejdstrivsel i relation til generel træthed i kroppen. En stor andel af køkkenmedarbejderne udtrykte dog ved slutmålingen, at økologiomlægningen havde betydet, at de følte sig...

  13. Decommissioning and dismantling of nuclear facilities. Experiences and perspectives. 3. new rev. ed.; Stilllegung und Rueckbau kerntechnischer Anlagen. Erfahrungen und Perspektiven

    Energy Technology Data Exchange (ETDEWEB)

    Thierfeldt, S.; Schartmann, F.

    2009-11-15

    The report on decommissioning and dismantling of German nuclear facilities includes nuclear power plants (Niederaichbach, Lingen, Greifswald, Rheinsberg, Gundremmingen-A, Kahl, Wuergassen, Stade, Obrigheim, Muehlheim-Kaerlich), test reactors, research reactors, and fuel cycle facilities. The following issues are discussed with respect to experiences and perspectives: waste management, legal frame work for the decommissioning of nuclear facilities, research funding and exchange of experiences, technologies for the dismantling of nuclear facilities, decommissioning challenges in an international context.

  14. anchovy Engraulis capensis, sardine Sardinops sa

    African Journals Online (AJOL)

    spamer

    gain through prolonged bouts of low-cost filter-feeding. (Van der Lingen ... 3 000-l fibreglass tank supplied with a continuous flow of 5-µm-filtered ... A sample of 20 fish was taken from each trawl to provide data on stomach contents at t = 0. Fish in the tank were observed to ensure that there was no feeding, and dead or ...

  15. JPRS Report, China

    National Research Council Canada - National Science Library

    1993-01-01

    ...; AGRICULTURE - Further Reform of Grain Circulation, Prices Advocated, Chen Yaobang on Market Challenges Facing Agriculture, Chen Yaobang on Restructuring of Crop Planting, MILITARY, PUBLIC SECURITY...

  16. Mobile Authoring of Open Educational Resources as Reusable Learning Objects

    Directory of Open Access Journals (Sweden)

    Dr Kinshuk

    2013-06-01

    Full Text Available E-learning technologies have allowed authoring and playback of standardized reusable learning objects (RLO for several years. Effective mobile learning requires similar functionality at both design time and runtime. Mobile devices can play RLO using applications like SMILE, mobile access to a learning management system (LMS, or other systems which deploy content to mobile learners (Castillo & Ayala, 2008; Chu, Hwang, & Tseng, 2010; Hsu & Chen, 2010; Nakabayashi, 2009; Zualkernan, Nikkhah, & Al-Sabah, 2009. However, implementations which author content in a mobile context do not typically permit reuse across multiple contexts due to a lack of standardization. Standards based (IMS and SCORM authoring implementations exist for non-mobile platforms (Gonzalez-Barbone & Anido-Rifon, 2008; Griffiths, Beauvoir, Liber, & Barrett-Baxendale, 2009; Téllez, 2010; Yang, Chiu, Tsai, & Wu, 2004. However, this paradigm precludes capturing learning where and when it occurs. Consequently, RLO authored for e-learning lack learner generated content, especially with timely, relevant, and location aware examples.

  17. Essential oil constituents of Etlingera yunnanensis and Hornstedtia sanhan grown in Vietnam.

    Science.gov (United States)

    Chau, Dao T M; Dai, Do N; Hoi, Tran M; Thai, Tran H; Thang, Tran D; Ogunwande, Isiaka A

    2015-02-01

    The chemical composition of the essential oils obtained from the hydrodistillation of different parts of Etlingera yunnanensis (T.L. Wu & S.J. Chen) R.M. Sm. and Hornstedtia sanhan M.F. Newman (Zingiberaceae) grown in Vietnam are reported. The analysis was performed by means of a gas chromatography-flame ionization detector (GC-FID) and gas chromatography coupled with mass spectrometry (GC-MS). The essential oil of the leaves of E. yunnanensis comprised mainly germacrene D (19.2%), β-pinene (11.6%), and α-amorphene (11.2%), while that of the stems was rich in β-pinene (23.7%), 1,8-cineole (11.0%) and α-pinene (9.6%). The major components of the root oil of E. yunnanensis were β-pinene (31.9%), α-pinene (13.7%) and 1,8-cineole (9.4%). However, α-pinene (25.9%, 36.3% and 14.1% for leaves, stems and roots, respectively), β-pinene (9.7%, 11.8% and 7.2% for leaves, stems and roots, respectively) and limonene (22.1%, 24.6% and 16.2% for leaves, stems and roots, respectively) were the major compounds of H. sanhan. In addition, α-humulene (15.9%) was present in larger amounts in the leaf oil while the root oil contained the largest proportion of methyl chavicol (43.7%).

  18. Harmonic Analysis : special program at the Nankai Institute of Mathematics

    CERN Document Server

    Deng, Dong-Gao; Zhou, Xing-Wei

    1991-01-01

    All papers in this volume are original (fully refereed) research reports by participants of the special program on Harmonic Analysis held in the Nankai Institute of Mathematics. The main themes include: Wavelets, Singular Integral Operators, Extemal Functions, H Spaces, Harmonic Analysis on Local Domains and Lie Groups, and so on. See also :G. David "Wavelets and Singular Integrals on Curves and Surfaces", LNM 1465,1991. FROM THE CONTENTS: D.C. Chang: Nankai Lecture in -Neumann Problem.- T.P. Chen, D.Z. Zhang: Oscillary Integral with Polynomial Phase.- D.G. Deng, Y.S. Han: On a Generalized Paraproduct Defined by Non-Convolution.- Y.S. Han: H Boundedness of Calderon-Zygmund Operators for Product Domains.- Z.X. Liu, S.Z. Lu: Applications of H|rmander Multiplier Theorem to Approximation in Real Hardy Spaces.- R.L. Long, F.S. Nie: Weighted Sobolev Inequality and Eigenvalue Estimates of Schr|dinger Operator.- A. McIntosh, Q. Tao: Convolution Singular Integral Operators on Lipschitz Curves.- Z.Y. Wen, L.M.Wu, Y.P. ...

  19. Diversity and uses of Zingiberaceae in Nam Nao National Park, Chaiyaphum and Phetchabun provinces, Thailand, with a new record for Thailand

    Directory of Open Access Journals (Sweden)

    Surapon Saensouk

    2016-11-01

    Full Text Available Three tribes, 12 genera and 38 species of the ginger family (Zingiberaceae along five routes in Nam Nao National Park were surveyed between January 2012 and December 2013 to determine their diversity, ecological data, phenology, uses and conservation status. The highest diversity was found in the tribe Zingibereae (6 genera and 21 species, of which the genera Curcuma and Zingiber comprised the highest number species (eight species each. A species key was constructed based on morphology. The ginger family was found in four forest-types—deciduous dipterocarp forest, mixed deciduous forest, dry evergreen forest and pine forest. The most flowering bloom of the ginger family in Nam Nao National Park was during March to August and the most fruiting bloom was during June to September. The popular uses of Zingiberaceae were as a food, spice, in medicine, as ornamentation and in rituals. Eight species have been evaluated as of least concern and are presented in the IUCN Red List, while two rare species were reported in Thailand Red Data: Plants, while six rare Zingiberaceae species were identified based on the evaluation criteria of Saensouk (2011. Four species were endemic to Thailand. Moreover, Etlingera yunnanensis (T. L. Wu & S. J. Chen R. M. Smith was a new record for Thailand.

  20. A Disseminação das Estratégias Corporativas Baseadas no Balanced Scorecard: Um Estudo de Caso em uma Empresa de Prestação de Serviços Ambientais

    Directory of Open Access Journals (Sweden)

    Maria do Carmo Assis Todorov

    2015-01-01

    Full Text Available  O balanced scorecard (BSC é uma ferramenta de medição de desempenho, desenvolvida por Norton e Kaplan (1997. Segundo Wu e Chen (2012, Zangoueinezhad e Moshabaki, (2011 e Galas e Forte (2005, o BSC é um método inovador de avaliação de desempenho empresarial, mas a disseminação de seus conceitos e indicadores para todos os níveis hierárquicos da organização, segundo Kaplan e Norton (1999, é um dos fatores críticos na sua implantação. Dentro desse contexto, esta pesquisa teve como objetivo analisar como ocorre a disseminação das estratégias corporativas baseadas no BSC por meio de um estudo de caso em uma empresa de prestação de serviços ambientais. Como resultado, destaca-se que a empresa estudada dissemina as estratégias corporativas por meio de um método organizacional inovador, o Prêmio de Excelência em Gestão, levando em conta as três dimensões da sustentabilidade (econômica, social e ambiental.  

  1. Two days of films

    CERN Document Server

    2011-01-01

    The Chinese community at CERN and the CERN CineClub, on the occasion of the Chinese New Year, invite everyone to two days of films Thursday 3 February 2011 at 20:30 - CERN Council Chamber Eat drink man woman Directed by Ang LEE (Taiwan, 1994) 122 min. With Sihung Lung, Yu-Wen Wang, Chien-Lien Wu, Kuei-Mei Yang Senior Master Chef Chu lives in a large house in Taipei with his three unmarried daughters, Jia-Jen, a chemistry teacher converted to Christianity, Jia-Chien, an airline executive, and Jia-Ning, a student who also works in a fast food restaurant. Life in the house revolves around the ritual of an elaborate dinner each Sunday, and the love lives of all the family members. Original version Mandarin with English subtitles Friday 4 February 2011 at 19:30 - CERN Council Chamber Adieu, ma concubine Directed by Chen KAIGE (China / Hong Kong, 1993) 171 min. With Leslie Cheung, Fengyi Zhang, Li Gong "Farewell, My Concubine" is a movie with two parallel, intertwined stories. It is the story of two performers in t...

  2. Research - African Journals Online

    African Journals Online (AJOL)

    raoul

    2011-12-14

    Dec 14, 2011 ... JinJian Fu1,2, SiDong Chen3,&, JiaLin Chen2, Jie Wang2, ChenWen Ling2. 1Department of Epidemiology, Southern Medical ... &Corresponding author: Sidong Chen, School of public health, Guangdong Pharmaceutical University, Guangzhou 510006,. Key words: Disease outbreaks, epidemiology, ...

  3. Categorizing renal oncocytic neoplasms on core needle biopsy: a morphologic and immunophenotypic study of 144 cases with clinical follow-up. Alderman MA, Daignault S, Wolf JS Jr, Palapattu GS, Weizer AZ, Hafez KS, Kunju LP, Wu AJ. Hum Pathol.September 2016;55:1-10.

    Science.gov (United States)

    Kryvenko, Oleksandr N

    2017-06-01

    There is limited literature on renal oncocytic neoplasms diagnosed on core biopsy. All renal oncocytic neoplasm core biopsies from 2006 to 2013 were, retrospectively, reviewed. Morphologic features and an immunohistochemical panel of CK7, c-KIT, and S100A1 were assessed. Concordance with resection diagnosis, statistical analysis including a random forest classification, and follow-up were recorded. The postimmunohistochemical diagnoses of 144 renal oncocytic core biopsies were favor oncocytoma (67%), favor renal cell carcinoma (RCC) (12%), and cannot exclude RCC (21%). Diagnosis was revised following immunohistochemistry in 7% of cases. The most common features for oncocytoma (excluding dense granular cytoplasm) were nested architecture, edematous stroma, binucleation and tubular architecture; the most common features for favor RCC were sheet-like architecture, nuclear pleomorphism, papillary architecture, and prominent cell borders. High nuclear grade, necrosis, extensive papillary architecture, raisinoid nuclei, and frequent mitoses were not seen in oncocytomas. Comparing the pathologist and random forest classification, the overall out-of-bag estimate of classification error dropped from 23% to 13% when favor RCC and cannot exclude RCC was combined into 1 category. Resection was performed in 19% (28 cases) with a 94% concordance (100% of favor RCC biopsies and 90% of cannot exclude RCC biopsies confirmed as RCC; 83% of favor oncocytomas confirmed); ablation in 23%; and surveillance in 46%. Follow-up was available in 92% (median follow-up, 33 months) with no adverse outcomes. Renal oncocytic neoplasms comprise a significant subset (16%) of all core biopsies, and the majority (78%) can be classified as favor oncocytoma or favor RCC. Copyright © 2017 Elsevier Inc. All rights reserved.

  4. 實徵研究/你用青春碰撞什麼?大學生閱讀行為的調查分析/黃焜煌;吳榮彬;張簡誌誠 | A Survey of the College Students' Reading Behavior in Taiwan/Kun-Huang Huarng;Jungpin Wu;Chih-Cheng Changchien

    Directory of Open Access Journals (Sweden)

    黃焜煌、吳榮彬、張簡誌誠 Kun-Huang Huarng; Jungpin Wu; Chih-Cheng Changchien

    2009-04-01

    Full Text Available 鑑於「閱讀」是學習者藉以獲取資訊來源、判讀知識內容、吸收經驗智慧的主要途徑,閱讀動機、能力以及風氣的強弱對於學習成效的影響甚巨,因此,希望透過較大規模的調查,以觀察現階段大學生閱讀行為的整體樣貌與發展趨勢。本文以自編問卷作為調查工具,大學在校學生為調查對象,在2008年2月18日至3月3日期間,選擇北、中、南10所大學院校,以無名冊的系統抽樣方式施測,總計發出1500份問卷,有效問卷1,077份,並利用SPSS統計軟體進行分析。本文以外在環境影響、內在個人因素以及行為產出結果等三個構面為主,同時針對圖書館、校園書店等閱讀補助機構進行分析與觀察,並據以描繪大學生閱讀行為的輪廓與問題,進而提供改善閱讀風氣的策略方案。The main purpose of this research is to explore the reading behavior of college students in Taiwan. The authors employed survey research method, and adopted a self-editing questionnaire, and used the systematic sampling to conduct the whole sampling survey. During February 18, 2008 to March 3, 2008, there were 1500 samples in total were surveyed. The number of the valid samples was 1077. Three factors consisted of the environmental factors, the individual factors, the outcome performance were used for data analysis. SPSS statistical software package was employed. This survey reported the college students’ reading behavior in Taiwan. Based on the research findings, the suggestions for reading improvement were proposed.頁次:37-54

  5. Commentary on "tissue-specific mutagenesis by N-butyl-N-(4-hydroxybutyl) nitrosamine as the basis for urothelial cell carcinogenesis." He Z, Kosinska W, Zhao ZL, Wu XR, Guttenplan JB, Department of Basic Science, New York University Dental College, NY, USA.: Mutat Res 2012;742(1-2):92-5 [Epub 2011 Dec 4].

    Science.gov (United States)

    Scherr, Douglas S

    2014-02-01

    Bladder cancer is one of the few cancers that have been linked to carcinogens in the environment and tobacco smoke. Of the carcinogens tested in mouse chemical carcinogenesis models, N-butyl-N-(4-hydroxybutyl)nitrosamine (BBN) is one that reproducibly causes high-grade, invasive cancers in the urinary bladder, but not in any other tissues. However, the basis for such a high-level tissue-specificity has not been explored. Using mutagenesis in lacI (Big Blue™) mice, we show here that BBN is a potent mutagen and it causes high-level of mutagenesis specifically in the epithelial cells (urothelial) of the urinary bladder. After a 2-6-week treatment of 0.05% BBN in the drinking water, mutagenesis in urothelial cells of male and female mice was about two orders of magnitude greater than the spontaneous mutation background. In contrast, mutagenesis in smooth muscle cells of the urinary bladder was about five times lower than in urothelial tissue. No appreciable increase in mutagenesis was observed in kidney, ureter, liver or forestomach. In lacI (Big Blue™) rats, BBN mutagenesis was also elevated in urothelial cells, albeit not nearly as profoundly as in mice. This provides a potential explanation as to why rats are less prone than mice to the formation of aggressive form of bladder cancer induced by BBN. Our results suggest that the propensity to BBN-triggered mutagenesis of urothelial cells underlies its heightened susceptibility to this carcinogen and that mutagenesis induced by BBN represents a novel model for initiation of bladder carcinogenesis. Copyright © 2014 Elsevier Inc. All rights reserved.

  6. 天津圖書館專輯/網上資源自由存取與圖書館服務/吳慰慈;谷秀潔 | Free Access to the Internet Resources and the Library Service Response/ Wei-Ci Wu;Xiu-Jie Gu

    Directory of Open Access Journals (Sweden)

    吳慰慈、谷秀潔

    2007-04-01

    Full Text Available

    網上資源自由存取有廣義和狹義兩種理解,它既是一種理性的權利也是一種理性的活動。儘管技術、民主、利益和全球化四條主線並不能完全概括網上資訊自 由存取所面臨的困難或成因,但是筆者將之作為一種分析問題的視角提出來供大家探討。最後,結台國內外實際情況對我國圖書館服務回應提出一些建議。

    There are two ways to understand the meaning of free access to the Internet resources: broad sense and narrow sense. The free access not only means a sort of rational rights but also a kind of rational activity. Although technology, democracy, benefit and globalization would not cover all reasons which restrict the free access to Internet resources, the authors just try to use them as analysis perspectives. Finally, according to the fact, they suggest some library service response stratagems.

    頁次:67-75

  7. Kimura's disease: A case presentation of postauricular swelling

    African Journals Online (AJOL)

    2015-05-28

    May 28, 2015 ... Chen YM, Chen CH, Chen HH, Chen YH, Chen DY, Lan JL. Clinical manifestations, therapeutic response and disease outcome of Kimura's disease in Taiwan. Formos J Rheumatol 2009;23:33‑9. 10. López‑Arcas Calleja JM, Iturriaga TM, Romero MP, de María Martínez G,. Martín‑Moro JG, del Castillo JL.

  8. Scattering of a spherical pulse from a small inhomogeneity ...

    Indian Academy of Sciences (India)

    R. Narasimhan (Krishtel eMaging Solutions)

    Lysmer and Drake 1972), the Born approximation (Wu and Aki 1985a), the complex screen approach. (Wu 1994), Kirchoff-Helmhotz integration (Neu- berg and Pointer 1995), the boundary integral equation method (Benites, Aki and Yamogida.

  9. Can Medical Herbs Stimulate Regeneration or Neuroprotection and Treat Neuropathic Pain in Chemotherapy-Induced Peripheral Neuropathy?

    National Research Council Canada - National Science Library

    Schröder, Sven; Beckmann, Kathrin; Franconi, Giovanna; Meyer-Hamme, Gesa; Friedemann, Thomas; Greten, Henry Johannes; Rostock, Matthias; Efferth, Thomas

    2013-01-01

    ..., Chamomilla matricaria, Ginkgo biloba, Salvia officinalis, Sweet bee venom, Fritillaria cirrhosae bulbus, and the herbal combinations Bu Yang Huan Wu, modified Bu Yang Huan Wu plus Liuwei Di Huang...

  10. 專論/台灣圖書館史數位圖書館建構之研究/王梅玲;蔡明月;陳志銘;柯雲娥;蔡佳縈;陳勇汀;林怡甄 | A Digital Library Pilot Study on Taiwan Libraries' History / Mei-Ling Wang; Ming-Yueh Tsay; Chih-Ming Chen; Yun-Er Ke; Chia-Ying Tsai; Yong-Ting Chen; Yi-Jen Lin

    Directory of Open Access Journals (Sweden)

    王梅玲、蔡明月、陳志銘、柯雲娥、蔡佳縈、陳勇汀、林怡甄

    2008-04-01

    Full Text Available

    圖書館是保存與詮釋人類文化重要的機構,1990 年代開始,網際網路的進步,促成數位圖書館蓬勃發展,有人預測它就是未來的圖書館,因此,圖書館界與教育界積極參與相關研究。台灣地區歷經日據時期、重建 時期、成長時期及茁壯時期四階段,建設許多圖書館,有其豐富的主題與素材值得發展成為數位圖書館。政治大學圖書資訊與檔案學研究所有鑑於此,提出「『台灣 百無圖書館史』數位圖書館」的構想,並獲得政大「發展國際一流大學及頂尖研究中心計畫」經費支持。本研究計畫目的包括:(1探索以台彎圖書館事業史為主 題的數位圖書館建構模式;(2建構數位圖書館以支援圖書資訊學教育與研究;(3研訂圖書館事業史料文獻的Metadata與數位資料格式;(4將圖 書文獻與文物數位化以建構數位館藏;(5發展數位圖書館系統與技術;(6研發數位圖書館網站的瀏覽與檢索功能;(7探討數位圖書館支援數位學習的模 式。計畫成果共研訂六種 Metadata標準:建置746筆數位化資料;以Dspace系統平台,依據需求設計台灣百年圖書館史系統架構與網站,最後提出結論與建議。

    Libraries are important social institutions that preserve and communicate human culture and knowledge. From the beginning of 1990s, the digital library has grown up rapidly based on the progress of the Internet. Libraries and educational institutions should be actively involved in digital library research and development. The Taiwan libraries’ history can be divided into four stages: Japanese occupation period, reconstruction period, growth period and strong period. In these processes, many events and libraries with rich materials that can be developed into a digital library. Graduate Institute of Library, Information and Archival Studies, National Chengchi University, planned the Digital Library Pilot Study on Taiwan Libraries’ History and got the university support. The pilot study objectives include: (1 exploring the digital library model on Taiwan libraries' history; (2 constructing digital library to support education and research in information and library science; (3 developing Metadata standards of library documents and heritage; (4 digitalizing documents and heritage to build digital collections (5 developing digital library systems and technology; (6 researching browsing and search functions of the digital library; (7 exploring the model of the digital library supports e-learning. In this pilot study, we developed six Metadata standards, built 746 digital resources, constructed a digital library system and web site, and proposed the conclusions and suggestions finally.

    頁次:15-38

  11. The 2nd International Conference on Agricultural and Biological Sciences (ABS 2016

    Directory of Open Access Journals (Sweden)

    Lei Pei

    2016-10-01

    Salvia of Labiatae in China Xiaojuan Li, Ning Xu, Guofu Zhou, Ming Wan, Qi Lin, Fanyun Meng, Jianxiu Li 15 Three pulling resistance models of pioneer plant in landslide area Yichang Chen, Koayung Yu, Chunpin Chang 16 The comparison of physiological and biochemical mechanisms of Reaumuria soongorica and Salsola passerine in different growth pattern Zijuan Zhou, Peixi Su, Rui Shi, Tingting Xie 17 Resources use efficiency of the cosmopolitan plant Potentilla anserina L. in different alpine habitats in China Rui Shi, Peixi Su, Zijuan Zhou 18 Cloning of PPDK gene from Red Amaranand transformation of Alfalfa Xuelan Liu, Yan Zhang, Xiangfa Wei 19 Variation and cluster analysis of morphological characters and nutrient content of Chucrasia tabularis seed Chong Wu, Yanlei Yin, Lijuan Feng, Xuemei Yang, Fei Wang 20 Effect of the planting density of the areca nut on the growth of intercropped Vanilla Hua Wang, Huifa Zhuang, Zihui Zhu, Hui Wang

  12. Insulin adherence and persistence among Chinese patients with type 2 diabetes: a retrospective database analysis

    Directory of Open Access Journals (Sweden)

    He X

    2017-02-01

    Full Text Available Xiaoning He,1 Liming Chen,2 Ke Wang,3 Haiya Wu,3 Jing Wu1 1Department of Health Pharmacy and Administration, School of Pharmaceutical Science and Technology, Tianjin University, Tianjin, 2Department of Metabolic Disease, Tianjin Medical University Metabolic Diseases Hospital, Tianjin, 3Medical Department, Lilly Suzhou Pharmaceutical Company, Ltd., Shanghai, People’s Republic of China Objective: To assess adherence and persistence to insulin therapy and identify its associated factors among Chinese insulin-naïve patients with type 2 diabetes (T2D. Methods: Tianjin Urban Employee Basic Medical Insurance claims database was used (2008–2011. Adult patients with T2D who initiated insulin therapy during January 2009 through December 2010 and were continuously enrolled for 12 months pre-(baseline and 12 months post-initiation (follow-up were included. Patients who had a ≥80% medication possession ratio were deemed adherent, while patients who had no gaps of ≥90 days in insulin therapy were deemed persistent. Associated factors of insulin adherence and persistence were detected by univariate and multivariate analyses. Results: A total of 24,192 patients were included; the patients had a mean age of 58.9 years, with 49.5% being female. About 51.9% of the patients had human insulin as initiation therapy, while 39.1% were initiated with insulin analog and 9.0% with animal-derived insulin. Premixed insulin (77.3% was prescribed most often in comparison with basal (11.8% and prandial (10.9% insulin. Only 30.9% of patients were adherent, and the mean (standard deviation medication possession ratio was 0.499 (0.361. About 53.0% of patients persisted insulin therapy during follow-up, and the mean time to nonpersistence was 230.3 (145.5 days. Patients initiated with analog were more likely to be adherent (adjusted odds ratio: 1.07, P=0.036 and persistent (adjusted hazard ratio: 0.88, P<0.001 compared with those initiated with human insulin. Patients

  13. Top five medical innovations in China mainland since Xinhai revolution [1911]: results of AME survey-002.

    Science.gov (United States)

    Wáng, Yì-Xiáng J; Xiao, Fan

    2015-06-01

    This survey aims to scrutinize important medical innovations in Chinese mainland since Xinhai (Hsin-hai) revolution in 1911, which marked the end of Manchurian imperial rule and the beginning of China's republican era. An online cross-sectional survey was carried out during the period of Dec 29, 2014 to Feb 5, 2015, totaling 37 days. The survey was conducted on the platform provided by DXY (www.dxy.cn), which is the largest medical and paramedical related website in China. An email was sent to all DXY registered users to invite them to participate in a 5-minute survey. The participants were asked to nominate up to four important medical innovations in China mainland since Xinhai revolution. The participant could select 'zero' which means he/she felt there was no important medical innovations, or he/she did not know important medical innovations. It was noted that important medical innovations refer to (I) those with practical and almost immediate significance to improve healthcare; (II) should not only be introducing western technique to China, but those involve major improvement of existing western techniques count; (III) should not be those with important theoretical discovery but did not have almost immediate significance to improve healthcare. In total 1,513 DXY users participated in the voting. Totally 489 (32.3%), 441 (29.1%), 342 (22.6%), 150 (9.9%), 91 (6.0%) participants provided 0, 1, 2, 3, 4 nominations respectively. (I) Artemisine (Qinghaosu) for malaria treatment (Project 523 team, 1972); (II) arsenic Trioxide (As2O3) for acute promyelocytic leukemia (APL) treatment (ZHANG Ting-Dong and colleagues, 1970s); (III) limb re-plantation (CHEN Zhong-Wei and colleagues, 1963); (IV) all-trans retinoic acid (ATRA) for APL treatment (WANG Zhen-Yi and colleagues, 1988); and (V) Wu's mask for plague prevention (WU Lien-The, 1910), were voted as the top five innovations in China mainland since Xinhai revolution, with 375, 96, 91, 53, and 8 votes respectively. In

  14. Olive oil in the prevention and treatment of osteoporosis after artificial menopause

    Directory of Open Access Journals (Sweden)

    Liu HL

    2014-12-01

    Full Text Available Huilan Liu,* Huijuan Huang,* Boheng Li, Dong Wu, Fengmei Wang, Xiao hua Zheng, Qingxia Chen, Bifang Wu, Xiaojie FanDepartment of Obstetrics and Gynecology, East Hospital, Xiamen University, Fuzhou, Fujian, People’s Republic of China*These authors contributed equally to this workPurpose: The goal of this study was to investigate the anti-osteoporosis effect of extra virgin olive oil (EVOO in vivo, and explore its antioxidant, anti-inflammatory properties in Sprague Dawley rats and its anticancer properties in patients.Materials and methods: A total of 120 healthy female Sprague Dawley rats aged 6 months were divided into four groups: 1 sham-operated control (Sham group, n=30; 2 ovariectomized (OVX group, n=30; 3 ovariectomized rats supplemented with EVOO (OVX + Olive, n=30; 4 ovariectomized rats supplemented with estrogen (OVX + E2, n=30. EVOO and estrogen were administered by oral gavage at a dose of 1 mL/100 g weight on a daily basis for 12 consecutive weeks. Twelve weeks later blood samples were obtained to detect the levels of calcium, alkaline phosphatase, phosphorus, interleukin-6 (IL-6, malonyldialdehyde (MDA, and nitrate content. Dual energy X-ray absorptiometer measured bone mineral density (BMD of ovariectomized Sprague Dawley rats that had been fed olive oil for 3 months. Blood samples from patients, who regularly consumed olive oil over a 1 year period were also used to measure carbohydrate antigen 125, carcino-embryonic antigen, α-fetoprotein, and carbohydrate antigen 19-9 levels. BMD of lumbar spine and left femur was also evaluated by dual energy X-ray absorptiometry.Results: Animal experiments showed that EVOO significantly increased BMD and decreased phosphatase, alkaline phosphatase, IL-6, MDA, and nitrate levels. However, it had no significant effect on the Ca2+ level. In clinical follow-up, EVOO also improved patient BMD levels on L3, L4, and left femoral neck, and reduced carbohydrate antigen 125,

  15. Annexin A1 is elevated in patients with COPD and affects lung fibroblast function

    Directory of Open Access Journals (Sweden)

    Lai TW

    2018-02-01

    Full Text Available Tianwen Lai,1,* Yanyu Li,1,* Zongjiong Mai,2 Xiaoxia Wen,1 Yingying Lv,1 Zhanqing Xie,3 Quanchao Lv,1 Min Chen,1 Dong Wu,1 Bin Wu1 1Department of Respiratory and Critical Care Medicine, 2Department of Oncology, 3Department of Thoracic Surgery, The Affiliated Hospital of Guangdong Medical University, Zhanjiang, People’s Republic of China *These authors contributed equally to this work Purpose: Fibrosis in peripheral airways is responsible for airflow limitation in chronic obstructive pulmonary disease (COPD. Annexin A1 modulates several key biological events during inflammation. However, little is known about its role in airway fibrosis in COPD. We investigated whether levels of Annexin A1 were upregulated in patients with COPD, and whether it promoted airway fibrosis.Methods: We quantified serum Annexin A1 levels in never-smokers (n=12, smokers without COPD (n=11, and smokers with COPD (n=22. Correlations between Annexin A1 expression and clinical indicators (eg, lung function were assessed. In vitro, human bronchial epithelial (HBE cells were exposed to cigarette smoke extract (CSE and Annexin A1 expression was assessed. Primary human lung fibroblasts were isolated from patients with COPD and effects of Annexin A1 on fibrotic deposition of lung fibroblasts were evaluated.Results: Serum Annexin A1 was significantly higher in patients with Global Initiative for Chronic Obstructive Lung Disease (GOLD guidelines stage III or IV than in those with GOLD stages I or II (12.8±0.8 ng/mL versus 9.8±0.7 ng/mL; p=0.016. Annexin A1 expression was negatively associated with airflow obstruction (forced expiratory volume in one second % predicted; r=−0.72, p<0.001. In vitro, Annexin A1 was significantly increased in CSE-exposed HBE cells in a time- and concentration-dependent manner. Annexin A1 promoted lung fibroblasts proliferation, migration, differentiation, and collagen deposition via the ERK1/2 and p38 mitogen-activated protein kinase pathways

  16. Cigarette smoke extract induces placental growth factor release from human bronchial epithelial cells via ROS/MAPK(ERK-1/2/Egr-1 axis

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    Wu D

    2016-12-01

    Full Text Available Dong Wu,1,* Yalian Yuan,1,* Zhixiu Lin,2,* Tianwen Lai,1 Min Chen,1 Wen Li,1 Quanchao Lv,1 Binfan Yuan,1 Dongmin Li,1 Bin Wu1 1Department of Respiratory, Institute of Respiratory Diseases, 2Department of Pharmacy, The Affiliated Hospital of Guangdong Medical University, Zhanjiang, People’s Republic of China *These authors contributed equally to this work Abstract: Etiological evidence demonstrates that there is a significant association between cigarette smoking and chronic airway inflammatory disease. Abnormal expression of placental growth factor (PlGF has been reported in COPD, and its downstream signaling molecules have been reported to contribute to the pathogenesis of airway epithelial cell apoptosis and emphysema. However, the signaling mechanisms underlying cigarette smoke extract (CSE-induced PlGF expression in airway microenvironment remain unclear. Herein, we investigated the effects of reactive oxygen species (ROS-dependent activation of the mitogen-activated protein kinase (MAPK (extracellular signal-regulated kinase1/2 [ERK-1/2]/early growth response-1 (Egr-1 pathway on CSE-induced PlGF upregulation in human bronchial epithelium (HBE. The data obtained with quantitative reverse transcription polymerase chain reaction, Western blot, enzyme-linked immunosorbent assay (ELISA and immunofluorescence staining analyses showed that CSE-induced Egr-1 activation was mainly mediated through production of ROS and activation of the MAPK (ERK-1/2 cascade. The binding of Egr-1 to the PlGF promoter was corroborated by an ELISA-based DNA binding activity assay. These results demonstrate that ROS activation of the MAPK (ERK-1/2/Egr-1 pathway is a main player in the regulatory mechanism for CSE-induced PlGF production and that the use of an antioxidant could partly abolish these effects. Understanding the mechanisms of PlGF upregulation by CSE in the airway microenvironment may provide rational therapeutic interventions for cigarette smoking

  17. Journal of Chemical Sciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Chemical Sciences. Gen Hua Wu. Articles written in Journal of Chemical Sciences. Volume 121 Issue 4 July 2009 pp 543-548. Highly sensitive optical chemosensor for the detection of Cu using a rhodamine B spirolatam · Gen Hua Wu Dong Xiang Wang Da Yu Wu Yuan Gao Zhu Qing Wang.

  18. Biisofraxidin on Apoptosis of Human Gastric Cancer BGC-823 Cells

    African Journals Online (AJOL)

    Power DG, Kelsen DP, Shah MA. Advanced gastric cancer show but steady progress. Cancer Treat Rev. 2010; 36: 384-392. 12. Yang L. Incidence and mortality of gastric cancer in. China. World J Gastroenterol 2006; 12: 17-20. 13. Leung WK, Wu MS, Kakugawa Y, Kim JJ, Yeoh KG, Goh. KL, Wu KC, Wu DC, Sollano J, ...

  19. Stereotactic body radiation therapy via helical tomotherapy to replace brachytherapy for brachytherapy-unsuitable cervical cancer patients – a preliminary result

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    Hsieh CH

    2013-02-01

    Full Text Available Chen-Hsi Hsieh,1–3 Hui-Ju Tien,1 Sheng-Mou Hsiao,4 Ming-Chow Wei,4 Wen-Yih Wu,4 Hsu-Dong Sun,4 Li-Ying Wang,5 Yen-Ping Hsieh,6 Yu-Jen Chen,3,7–9 Pei-Wei Shueng1,101Department of Radiation Oncology, Far Eastern Memorial Hospital, Taipei, Taiwan; 2Department of Medicine, 3Institute of Traditional Medicine, School of Medicine, National Yang-Ming University, Taipei, Taiwan; 4Department of Obstetrics and Gynecology, Far Eastern Memorial Hospital, Taipei, Taiwan; 5School and Graduate Institute of Physical Therapy, College of Medicine, National Taiwan University, Taipei, Taiwan; 6Department of Senior Citizen Service Management, National Taichung University of Science and Technology, Taichung, Taiwan; 7Department of Radiation Oncology, 8Department of Medical Research, Mackay Memorial Hospital, Taipei, Taiwan; 9Graduate Institute of Sport Coaching Science, Chinese Culture University, Taipei, Taiwan; 10Department of Radiation Oncology, National Defense Medical Center, Taipei, TaiwanAim: To review the experience and to evaluate the results of stereotactic body radiation therapy (SBRT via helical tomotherapy (HT, for the treatment of brachytherapy-unsuitable cervical cancer.Methods: Between September 1, 2008 to January 31, 2012, nine cervical cancer patients unsuitable for brachytherapy were enrolled. All of the patients received definitive whole pelvic radiotherapy with or without chemotherapy, followed by SBRT via HT.Results: The actuarial locoregional control rate at 3 years was 78%. The mean biological equivalent dose in 2-Gy fractions of the tumor, rectum, bladder, and intestines was 76.0 ± 7.3, 73.8 ± 13.2, 70.5 ± 10.0, and 43.1 ± 7.1, respectively. Only two had residual tumors after treatment, and the others were tumor-free. Two patients experienced grade 3 acute toxicity: one had diarrhea; and another experienced thrombocytopenia. There were no grade 3 or 4 subacute toxicities. Three patients suffered from manageable rectal bleeding in

  20. Radiobiological evaluation of simultaneously dose-escalated versus non-escalated intensity-modulated radiation therapy for patients with upper thoracic esophageal cancer

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    Huang BT

    2017-04-01

    Full Text Available Bao-Tian Huang,1,* Li-Li Wu,1,* Long-Jia Guo,1,* Liang-Yu Xu,1,* Rui-Hong Huang,1 Pei-Xian Lin,2 Jian-Zhou Chen,1,3 De-Rui Li,1 Chuang-Zhen Chen1 1Department of Radiation Oncology, Cancer Hospital of Shantou University Medical College, Shantou, 2Department of Nosocomial Infection Management, The Second Affiliated Hospital of Shantou University Medical College, Shantou, People’s Republic of China; 3CRUK/MRC Oxford Institute for Radiation Oncology, University of Oxford, Oxford, United Kingdom *These authors contributed equally to this work Objective: To compare the radiobiological response between simultaneously dose-escalated and non-escalated intensity-modulated radiation therapy (DE-IMRT and NE-IMRT for patients with upper thoracic esophageal cancer (UTEC using radiobiological evaluation. Methods: Computed tomography simulation data sets for 25 patients pathologically diagnosed with primary UTEC were used in this study. DE-IMRT plan with an escalated dose of 64.8 Gy/28 fractions to the gross tumor volume (GTV and involved lymph nodes from 25 patients pathologically diagnosed with primary UTEC, was compared to an NE-IMRT plan of 50.4 Gy/28 fractions. Dose-volume metrics, tumor control probability (TCP, and normal tissue complication probability for the lung and spinal cord were compared. In addition, the risk of acute esophageal toxicity (AET and late esophageal toxicity (LET were also analyzed. Results: Compared with NE-IMRT plan, we found the DE-IMRT plan resulted in a 14.6 Gy dose escalation to the GTV. The tumor control was predicted to increase by 31.8%, 39.1%, and 40.9% for three independent TCP models. The predicted incidence of radiation pneumonitis was similar (3.9% versus 3.6%, and the estimated risk of radiation-induced spinal cord injury was extremely low (<0.13% in both groups. Regarding the esophageal toxicities, the estimated grade ≥2 and grade ≥3 AET predicted by the Kwint model were increased by 2.5% and 3.8%. Grade ≥2

  1. Meta-analysis of postoperative adjuvant chemotherapy without radiotherapy in early stage non-small cell lung cancer

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    Chen YY

    2015-08-01

    Full Text Available Yuan-Yuan Chen,* Lin-Wei Wang,* Shu-Yi Wang, Bi-Bo Wu, Zhen-Meng Wang, Fang-Fang Chen, Bin Xiong Department of Oncology, Zhongnan Hospital of Wuhan University, Hubei Key Laboratory of Tumor Biological Behaviors and Hubei Cancer Clinical Study Center, Wuhan, Hubei, People’s Republic of China *These authors contributed equally to this work Background: Many clinical trials have confirmed that postoperative adjuvant therapy can prolong survival of non-small cell lung cancer. However, the efficiency of postoperative chemotherapy without radiotherapy is unclear, especially in early stage (stages I and II. We aimed to assess the effect of postoperative chemotherapy without radiotherapy in early stage patients.Methods: Databases and manual searches were adopted to identify eligible randomized control trials. Hazard ratio (HR was used to assess the advantage of disease-free survival (DFS and overall survival (OS by fixed or random-effects models.Results: Fourteen trials with 3,923 patients were included based on inclusion criteria. Compared with surgery alone, postoperative chemotherapy significantly improved DFS and OS with HR of 0.71 (P=0.005 and 0.74 (P<0.00001, respectively. Subgroup analysis showed both cisplatin-based (HR: 0.75, P<0.0001 and single tegafur–uracil (UFT chemotherapy (HR: 0.72, P=0.002 yielded significant survival benefits, but the latter did not improve DFS (HR: 1.04, P=0.81. Indirect treatment comparison showed cisplatin-based chemotherapy was superior to single UFT in DFS, but comparable in OS. The benefits of postoperative chemotherapy were maintained in patients in stage I (HR: 0.74, P<0.00001 and IB (HR: 0.74, P=0.0003, but not in stage IA, although the trend supported chemotherapy (HR: 0.76, P=0.43.Conclusion: This meta-analysis demonstrates that postoperative chemotherapy without radiotherapy improves survival of stage I–II, I, and IB non-small cell lung cancer patients, but not for IA. Meanwhile, efficacy of cisplatin

  2. Effectiveness of neuromuscular electrical stimulation for the rehabilitation of moderate-to-severe COPD: a meta-analysis

    Directory of Open Access Journals (Sweden)

    Chen R

    2016-11-01

    Full Text Available Rong-chang Chen,1,* Xiao-ying Li,1,* Li-li Guan,1 Bing-peng Guo,1 Wei-liang Wu,1 Zi-qing Zhou,1 Ya-ting Huo,1 Xin Chen,2 Lu-qian Zhou1 1State Key Laboratory of Respiratory Disease, Guangzhou Institute of Respiratory Disease, First Affiliated Hospital of Guangzhou Medical University, 2Zhujiang Hospital of Southern Medical University, Guangzhou, People’s Republic of China *These authors contributed equally to this work Purpose: Patients with COPD often experience skeletal muscle dysfunction. For those who are unable or unwilling to undertake physical training, neuromuscular electrical stimulation (NMES may provide an alternative method of rehabilitation. The purpose of this meta-analysis was to investigate the controversial topic of whether this therapy is effective in patients with moderate-to-severe COPD. Patients and methods: We pooled data from nine trials published between January 9, 2002 and January 4, 2016 across PubMed, Embase, Cochrane Central Register of Controlled Trials, Google Scholar, and relevant websites for randomized controlled trials. In these trials, patients with moderate-to-severe COPD were randomly allocated to receive NMES. Primary outcomes were quadricep strength and exercise capacity. The secondary outcome was health-related quality of life. Results: We extracted data from 276 patients. NMES contributed to statistically improved quadricep strength (standardized mean difference 1.12, 95% confidence interval [CI] 0.64–1.59, I2=54%; P>0.00001 and exercise capacity, including longer exercise distance (weighted mean difference 51.53, 95% CI 20.13–82.93, I2=90%; P=0.001, and longer exercise endurance (standardized mean difference 1.11, 95% CI 0.14–2.08, I2=85%; P=0.02. There was no significant difference in St George’s Respiratory Questionnaire scores (weighted mean difference -0.07, 95% CI -2.44 to 2.30, I2=56%; P=0.95. Conclusion: NMES appears an effectual means of enhancing quadricep strength and exercise

  3. Clinical effectiveness, toxicity, and failure patterns of helical tomotherapy for postoperative oral cavity cancer patients

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    Hsieh CH

    2014-03-01

    Full Text Available Chen-Hsi Hsieh,1–3 Pei-Wei Shueng,1,4 Li-Ying Wang,5 Li-Jen Liao,6 Yu-Chin Lin,7 Ying-Shiung Kuo,8 Wu-Chia Lo,6 Chien-Fu Tseng,8 Hui-Ju Tien,1 Hsiu-Ling Chou,9,10 Yen-Ping Hsieh,11 Le-Jung Wu,1 Yu-Jen Chen3,12–14 1Department of Radiation Oncology, Far Eastern Memorial Hospital, 2Department of Medicine, 3Institute of Traditional Medicine, School of Medicine, National Yang-Ming University, 4Department of Radiation Oncology, National Defense Medical Center, 5School and Graduate Institute of Physical Therapy, College of Medicine, National Taiwan University, 6Department of Otolaryngology, 7Division of Medical Oncology and Hematology, Department of Internal Medicine, 8Department of Dentistry and Oral Surgery, 9Department of Nursing, Far Eastern Memorial Hospital, 10Department of Nursing, Oriental Institute of Technology, Taipei, 11Department of Senior Citizen Service Management, National Taichung University of Science and Technology, Taichung, 12Department of Radiation Oncology, 13Department of Medical Research, Mackay Memorial Hospital, 14Graduate Institute of Sport Coaching Science, Chinese Culture University, Taipei, Taiwan Background: The outcome of postoperative high- and intermediate-risk oral cavity cancer (OCC patients receiving helical tomotherapy (HT remains limited. Materials and methods: Between November 2006 and November 2012, 53 postoperative high- and intermediate-risk OCC patients treated with HT were enrolled. Results: The 4-year locoregional, local, and regional control rates were 66%, 76.4%, and 94.3%, respectively. The 4-year locoregional control rates of oral tongue and buccal mucosa cancer were 88.3% and 37.1%, respectively (P=0.012. Eleven (20.8% patients experienced locoregional failure. In-field failure occurred in six of 53 (11.3% in the primary area and three of 53 (5.7% in the regional lymph-node area. No marginal failure was noted. Two of 53 (3.8% experienced out-of-field failure. The rates of grade 3 dermatitis

  4. Mir-434-5p mediates skin whitening and lightening

    Directory of Open Access Journals (Sweden)

    David TS Wu

    2008-10-01

    Full Text Available David TS Wu, Jack S Chen, Donald C Chang, Shi-Lung LinInstitute of Mello Biotechnology, Taipei, Taiwan, ROCAbstract: Utilization of gene silencing effectors, such as microRNA (miRNA and small airpin RNA (shRNA, provides a powerful new strategy for human skin care in vivo, particularly for hyperpigmentation treatment and aging prevention. In this study, tyrosinase (Tyr, the rate-limiting enzyme of melanin (black pigment biosynthesis, was served as a target for treatment of hyperpigmentation in mouse and human skins. There are over 54 native microRNA capable of silencing human tyrosinase for skin whitening and lightening. To this, we have designed a mir-434-5p homologue and used it to successfully demonstrate the feasibility of miRNA-mediated skin whitening and lightening in vitro and in vivo. Under the same experimental condition in the trials, Pol-II-directed intronic mir-434-5p expression did not cause any detectable sign of cytotoxicity, whereas siRNAs targeting the same sequence often induced certain nonspecific mRNA degradation as previously reported. Because the intronic miRNA-mediated gene silencing pathway is tightly regulated by multiple intracellular surveillance systems, including Pol-II transcription, RNA splicing, exosomal digestion and nonsense-mediated RNA decay (NMD, the current findings underscore the fact that intronic miRNA agents, such as manually re-designed mir-434-5p homologues, are effective, target-specific and safe to be used for skin whitening without any detectable cytotoxic effect. Given that the human skins also express a variety of other native miRNAs, we may re-design these miRNAs based on their individual functions for skin care, which may provide significant insights into areas of opportunity for new cosmetic and/or therapeutical applications.Keywords: microRNA, miRNA, mir-434, intron, gene silencing, RNAi, tyrosinase, melanin, cosmetics, pigmentation, skin whitening

  5. A study of the law of herbal administration in treating lung-distension by TCM physicians through history using cluster analysis.

    Science.gov (United States)

    Gao, Zhen; Li, Feng-Sen; Upur, Halmurat

    2011-12-01

    To review the herbal drugs used most often for treating lung-distension by determining those used by physicians throughout history; to study their property, taste, and channel tropism; and to explore their compatibility. Historical prescriptions for treating lung-distension were collected and sorted. Property, taste and channel tropism were determined, and the law of herbal administration was determined by cluster analysis. One hundred and ninety five prescriptions were found, involving 166 herbal drugs, with a total appearance frequency of 1296 drugs. The herbs involved 8 properties (total appearance frequency, 1296), 7 forms of taste (total appearance frequency, 1991) and involved all 12 regular channels (total appearance frequency, 3382). Sixteen herbal drugs were used most often and formed 4 cluster prescriptions: C1: Xing Ren (Semen Armeniacae Amarum), Gan Cao (Radix Glycyrrhizae), and Ban Xia (Rhizoma Pinelliae); C2: Gui Zhi (Ramulus Cinnamomi), Wu Wei Zi (Fructus Schisandrae), and Sheng Jiang (Rhizoma Zingiberis Recens); C3: Da Zao (Fructus Jujubae), Ma Huang (Herba Ephedrae), and Shi Gao (Gypsum Fibrosum); and C4: Chen Pi (Pericarpium Citri Reticulatae), Jie Geng (Radix Platycodi), Fu Ling (Poria), Sang Bai Pi (Cortex Mori), Xi Xin (Herba Asari), Gan Jiang (Rhizoma Zingiberis), and Bai Shao (Radix Paeoniae Alba). In treating lung-distension, phlegm retention has been traditionally considered the underlying pathology, emphasizing regulation of the lung and spleen as key and stressing patient nourishment and mental improvement. Prescriptions for lung-distension should be made with reference to the property, taste, channel tropism, and effectiveness of the chosen herbal drugs.

  6. Expression profiles and initial confirmation of long noncoding RNAs in Chinese patients with pulmonary adenocarcinoma

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    Zhao X

    2014-07-01

    Full Text Available Xin Zhao,* Wen Zhu,* Wangjian Zha, Feifei Chen, Zhenzhen Wu, Yanan Liu, Mao Huang Department of Respiratory Medicine, The First Affiliated Hospital, Nanjing Medical University, Nanjing, People’s Republic of China *These authors contributed equally to this study and share first authorship Background: The purpose of this study was to investigate differentially expressed long noncoding RNAs (lncRNAs in pulmonary adenocarcinoma tissue and adjacent noncancerous tissue from Chinese patients using lncRNA expression microarray and preliminary analysis. Methods: RNA extracted from three paired pulmonary adenocarcinoma tissue and adjacent noncancerous tissue specimens was used to synthesize double-stranded complementary DNA after labeling and hybridization. The complementary DNA was labeled and hybridized to the lncRNA expression microarray, and array data were analyzed for hierarchical clustering. Gene coexpression networks were constructed to identify interactions among genes. To validate the microarray findings, we measured the relative expression levels of four random differentially expressed lncRNAs in the same tissue used for microarray using real-time quantitative polymerase chain reaction. The expression level of one lncRNA, AK124939, in the paired pulmonary adenocarcinoma/adjacent noncancerous tissue of another 30 patients was measured using real-time quantitative polymerase chain reaction. The experimental data were further analyzed and compared with clinical features. Results: Of 39,000 lncRNAs investigated, 704 were differentially expressed in pulmonary adenocarcinoma tissue; 385 were upregulated and 319 were downregulated compared with those in the adjacent noncancerous tissue (fold change ≥2 and ≤–2, P<0.05. AK124939 expression levels in poorly differentiated adenocarcinoma tissue were lower than those found in well to moderately differentiated adenocarcinoma tissue (P=0.05. Conclusion: There are significant differences in the lnc

  7. Platelet–lymphocyte ratios: a potential marker for pulmonary tuberculosis diagnosis in COPD patients

    Directory of Open Access Journals (Sweden)

    Chen G

    2016-11-01

    Full Text Available Guozhong Chen, Chunling Wu, Zhiying Luo, Yiming Teng, Suping Mao Department of Respiratory Medicine, Yiwu Central Hospital, Yiwu, Zhejiang Province, People’s Republic of China Background: In recent decades, morbidity and mortality have been found to be significantly increased in patients with chronic obstructive pulmonary disease (COPD complicated with pulmonary tuberculosis (PTB. Platelet–lymphocyte ratio (PLR is an indicator for inflammatory diseases. This study aims to investigate whether PLR could act as a potential marker for patients with COPD complicated with PTB.Methods: In this retrospective study, laboratory characteristics of 87 COPD patients complicated with PTB (determined by Mycobacterium tuberculosis positive culture from sputum or bronchial lavage fluid and 83 COPD patients (as the control group, determined by M. tuberculosis culture negativity from sputum or bronchial lavage fluid were investigated. Data obtained on the day of admission were analyzed.Results: PLR >216.82 was identified as the optimal cutoff value for discriminating COPD patients with PTB (sensitivity 92.4%, specificity 84.5%, positive-predictive value 91.6%, negative-predictive value 86.2%, and area under the curve [AUC] was 0.87 from patients with COPD alone. The AUC of PLR was significantly greater than that of neutrophil–lymphocyte count ratio (AUC, 0.74; 95% confidence interval, 0.67–0.81; P<0.01.Conclusion: PLR could be developed as a valuable maker for identifying tuberculosis infection in COPD patients. Keywords: platelet to lymphocyte ratio, pulmonary tuberculosis, chronic obstructive pulmonary disease

  8. Research on simulation and experiment of noninvasive intracranial pressure monitoring based on acoustoelasticity effects

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    Wu J

    2013-08-01

    Full Text Available Jun Wu1, Wei He2, Wei-min Chen1, Lian Zhu21Key Laboratory of Optoelectronic Technology and Systems, 2State Key Laboratory of Power Transmission Equipment and System Security and New Technology, Chongqing University, Chongqing, People’s Republic of ChinaAbstract: The real-time monitoring of intracranial pressure (ICP is very important for craniocerebrally critically ill patients, but it is very difficult to realize long-time monitoring for the traditional invasive method, which very easily infects patients. Many noninvasive methods have emerged, but these have not been able to monitor ICP for long periods in real time, and they are not ready for clinical application. In order to realize long-time, online, real-time, noninvasive monitoring for ICP, a new method based on acoustoelasticity of ultrasound is herein proposed. Experimental models were devised to research the new method for experiment and simulation. Polymethyl methacrylate and hydrogel were adopted for the experiment, and their mechanical properties were very close to the real brain. A numerical solution for acoustoelasticity theory was acquired by simulating calculation based on a finite-element method. This was compared to the experimental value. The results showed a consistent match between theoretical solution and experimental value, with maximum error at most 5%. Thus, the effectiveness of the new method was verified. Theoretical and practical foundation is provided for this new method, and it could be used for animal experimentation or clinical testing in further research.Keywords: medical instruments, noninvasive, intracranial pressure, ultrasonic, acoustoelasticity, biomechanics

  9. The History, Status, Gaps, and Future Directions of Neurotoxicology in China.

    Science.gov (United States)

    Cai, Tongjian; Luo, Wenjing; Ruan, Diyun; Wu, Yi-Jun; Fox, Donald A; Chen, Jingyuan

    2016-06-01

    Rapid economic development in China has produced serious ecological, environmental, and health problems. Neurotoxicity has been recognized as a major public health problem. The Chinese government, research institutes, and scientists conducted extensive studies concerning the source, characteristics, and mechanisms of neurotoxicants. This paper presents, for the first time, a comprehensive history and review of major sources of neurotoxicants, national bodies/legislation engaged, and major neurotoxicology research in China. Peer-reviewed research and pollution studies by Chinese scientists from 1991 to 2015 were examined. PubMed, Web of Science and Chinese National Knowledge Infrastructure (CNKI) were the major search tools. The central problem is an increased exposure to neurotoxicants from air and water, food contamination, e-waste recycling, and manufacturing of household products. China formulated an institutional framework and standards system for management of major neurotoxicants. Basic and applied research was initiated, and international cooperation was achieved. The annual number of peer-reviewed neurotoxicology papers from Chinese authors increased almost 30-fold since 2001. Despite extensive efforts, neurotoxicity remains a significant public health problem. This provides great challenges and opportunities. We identified 10 significant areas that require major educational, environmental, governmental, and research efforts, as well as attention to public awareness. For example, there is a need to increase efforts to utilize new in vivo and in vitro models, determine the potential neurotoxicity and mechanisms involved in newly emerging pollutants, and examine the effects and mechanisms of mixtures. In the future, we anticipate working with scientists worldwide to accomplish these goals and eliminate, prevent and treat neurotoxicity. Cai T, Luo W, Ruan D, Wu YJ, Fox DA, Chen J. 2016. The history, status, gaps, and future directions of neurotoxicology in

  10. Use of select medications prior to duloxetine initiation among commercially-insured patients

    Directory of Open Access Journals (Sweden)

    Bernauer M

    2012-08-01

    Full Text Available Mark Bernauer,1 Ning Wu,2 Shih-Yin Chen,2 Xiaomei Peng,1 Luke Boulanger,2 Yang Zhao11Eli Lilly and Company, Indianapolis, IN, 2United BioSource Corporation, Lexington, MA, USABackground: The purpose of this study was to assess select medication utilization prior to duloxetine initiation among patients with major depressive disorder, generalized anxiety disorder, diabetic peripheral neuropathic pain, fibromyalgia, and musculoskeletal pain associated with osteoarthritis or low back pain.Methods: Commercially insured duloxetine initiators between January 1, 2007 and March 31, 2010 were identified from a large US administrative claims database. Disease subgroups were constructed based on diagnosis from medical claims during the 12 months prior to duloxetine initiation. Prior use of antidepressants, anticonvulsants, opioids, nonsteroidal anti-inflammatory drugs, and muscle relaxants was assessed during the 12-month preinitiation period.Results: This study identified 56,845 (2007, 44,838 (2008, and 65,840 (January 2009 to March 2010 duloxetine initiators. Among the 2009 initiators, utilization patterns were similar for patients with major depressive disorder and generalized anxiety disorder, with antidepressants being the most used (84% and 80%, respectively, followed by opioids (58% and 55%, respectively. Patients across pain-related conditions also had similar utilization patterns, with opioid use being the highest (76%–82%, followed by antidepressants (65%–72%. Use of other medication classes was common (29%–63% but less frequent, and over 50% of the patients used any antidepressants, 70% used any antidepressants or anticonvulsants, and 90% used any antidepressants, anticonvulsants, or opioids. Trends in the use of these select medications were similar between 2007 and 2009.Conclusion: Patients used several types of medications over the 12 months prior to initiating duloxetine across disease states, with antidepressants and opioids being the

  11. Tumor necrosis factor α modulates sodium-activated potassium channel SLICK in rat dorsal horn neurons via p38 MAPK activation pathway

    Directory of Open Access Journals (Sweden)

    Wang K

    2017-05-01

    Full Text Available Kun Wang,1 Feng Wang,1 Jun-Ping Bao,2 Zhi-Yang Xie,1 Lu Chen,1 Bao-Yi Zhou,1 Xin-Hui Xie,2 Xiao-Tao Wu1,2 1Medical School of Southeast University, 2Department of Orthopaedics, Zhongda Hospital, Southeast University, Nanjing, People’s Republic of China Abstract: The dorsal horn (DH of the spinal cord is the integrative center that processes and transmits pain sensation. Abnormal changes in ion channel expression can enhance the excitability of pain-related DH neurons. Sodium-activated potassium (KNa channels are highly expressed particularly in the central nervous system; however, information about whether rat DH neurons express the SLICK channel protein is lacking, and the direct effects on SLICK in response to inflammation and the potential signaling pathway mediating such effects are yet to be elucidated. Here, using cultured DH neurons, we have shown that tumor necrosis factor-α inhibits the total outward potassium current IK and the KNa current predominantly as well as induces a progressive loss of firing accommodation. However, we found that this change in channel activity is offset by the p38 inhibitor SB202190, thereby suggesting the modulation of SLICK channel activity via the p38 MAPK pathway. Furthermore, we have demonstrated that the tumor necrosis factor-α modulation of KNa channels does not occur at the level of SLICK channel gating but arises from possible posttranslational modification. Keywords: p38 MAPK, SLICK channel, neuropathic pain, dorsal horn, TNF-α

  12. Purification and in vitro antioxidant activities of tellurium-containing phycobiliproteins from tellurium-enriched Spirulina platensis

    Directory of Open Access Journals (Sweden)

    Yang F

    2014-10-01

    Full Text Available Fang Yang,1 Ka-Hing Wong,2 Yufeng Yang,3 Xiaoling Li,1 Jie Jiang,1 Wenjie Zheng,1 Hualian Wu,1 Tianfeng Chen1 1Department of Chemistry, Jinan University, Guangzhou, People’s Republic of China; 2Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hong Kong, People’s Republic of China; 3Institute of Hydrobiology, College of Life Science and Technology, Jinan University, Guangzhou, People’s Republic of China Abstract: Tellurium-containing phycocyanin (Te-PC and allophycocyanin (Te-APC, two organic tellurium (Te species, were purified from tellurium-enriched Spirulina platensis by a fast protein liquid chromatographic method. It was found that the incorporation of Te into the peptides enhanced the antioxidant activities of both phycobiliproteins. With fractionation by ammonium sulfate precipitation and hydroxylapatite chromatography, Te-PC and Te-APC could be effectively separated with high purity, and Te concentrations were 611.1 and 625.3 µg g-1 protein in Te-PC and Te-APC, respectively. The subunits in the proteins were identified by using MALDI-TOF-TOF mass spectrometry. Te incorporation enhanced the antioxidant activities of both phycobiliproteins, as examined by 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid assay. Moreover, Te-PC and Te-APC showed dose-dependent protection on erythrocytes against the water-soluble free radical initiator 2,2'-azo(2-asmidinopropanedihydrochloride-induced hemolysis. In the hepatoprotective model, apoptotic cell death and nuclear condensation induced by tert-butyl hydroperoxide in HepG2 cells was significantly attenuated by Te-PC and Te-APC. Taken together, these results suggest that Te-PC and Te-APC are promising Te-containing proteins with application potential for treatment of diseases related to oxidative stress. Keywords: tellurium, phycocyanin, allophycocyanin, purification, antioxidant activity

  13. Combining structure-based pharmacophore modeling, virtual screening, and in silico ADMET analysis to discover novel tetrahydro-quinoline based pyruvate kinase isozyme M2 activators with antitumor activity

    Directory of Open Access Journals (Sweden)

    Chen C

    2014-09-01

    Full Text Available Can Chen,1,2,* Ting Wang,1,3,* Fengbo Wu,1,* Wei Huang,4 Gu He,1 Liang Ouyang,1 Mingli Xiang,1 Cheng Peng,4 Qinglin Jiang1,2 1State Key Laboratory of Biotherapy and Department of Pharmacy, West China Hospital, Sichuan University, Chengdu, 2College of Pharmacy and the First Affiliated Hospital, Chengdu Medical College, Chengdu, 3Department of Cardiology, Genenal Hospital of Chengdu Military Command, Chengdu, 4State Key Laboratory Breeding Base of Systematic Research, Development and Utilization of Chinese Medicine, Chengdu University of Traditional Chinese Medicine, Chengdu, People’s Republic of China*These authors contributed equally to this workAbstract: Compared with normal differentiated cells, cancer cells upregulate the expression of pyruvate kinase isozyme M2 (PKM2 to support glycolytic intermediates for anabolic processes, including the synthesis of nucleic acids, amino acids, and lipids. In this study, a combination of the structure-based pharmacophore modeling and a hybrid protocol of virtual screening methods comprised of pharmacophore model-based virtual screening, docking-based virtual screening, and in silico ADMET (absorption, distribution, metabolism, excretion and toxicity analysis were used to retrieve novel PKM2 activators from commercially available chemical databases. Tetrahydroquinoline derivatives were identified as potential scaffolds of PKM2 activators. Thus, the hybrid virtual screening approach was applied to screen the focused tetrahydroquinoline derivatives embedded in the ZINC database. Six hit compounds were selected from the final hits and experimental studies were then performed. Compound 8 displayed a potent inhibitory effect on human lung cancer cells. Following treatment with Compound 8, cell viability, apoptosis, and reactive oxygen species (ROS production were examined in A549 cells. Finally, we evaluated the effects of Compound 8 on mice xenograft tumor models in vivo. These results may provide important

  14. Antibody targeting of TSG101 on influenza-infected cells

    Directory of Open Access Journals (Sweden)

    Aurelio Bonavia

    2010-11-01

    Full Text Available Aurelio Bonavia1*, Leyla S Diaz1*, David Santos1, Josephine Cassella1, Zena Fesseha1, Douty Bamba1, Baoquan Sui1, Wu-Bo Li1, Roxanne Duan1, Li-Mei Chen2, Ruben O Donis2, Michael Goldblatt1, Michael S Kinch11Functional Genetics, Inc, Gaithersburg, MD, USA; 2Influenza Division, Centers for Disease Control and Prevention, Atlanta, GA, USA; *These authors contributed equally to this work.Abstract: Influenza remains a significant cause of morbidity and mortality worldwide. Although vaccination programs and conventional antiviral therapies can reduce disease burden, increasing resistance to conventional therapies renders much of the population susceptible to infection. The present study focuses on an important host protein target, tumor susceptibility gene 101 (TSG101, which is functionally exploited (hijacked by certain enveloped viruses to facilitate viral budding and release. We find that influenza viruses depend on TSG101 for progeny virion morphogenesis in infected host cells. Antibody-binding studies revealed that TSG101 is exposed at the surface of influenza-infected cells but remains intracellular in uninfected cells. Using recombinant TSG101 and influenza M1 protein, we demonstrated a direct interaction between these proteins involving the ubiquitin E2 variant domain of TSG101. These findings identify an interaction between TSG101 and M1 protein in infected cells. Furthermore, a monoclonal antibody directed against TSG101 reduced virus yields in cell-based assessment of influenza virus infection, underscoring the potential of the TSG101-M1 interaction as a possible antiviral therapeutic target. The display of TSG101 at the surface of infected cells, combined with evidence that TSG101 antibodies reduce virus yields, suggest that TSG101 plays an essential role in the budding process of influenza virus. Our findings may also suggest potential opportunities for influenza treatment and prevention by using monoclonal antibody therapeutics to

  15. Efficacy and safety of ultrasound-guided continuous hyperthermic intraperitoneal perfusion chemotherapy for the treatment of malignant ascites: a midterm study of 36 patients

    Directory of Open Access Journals (Sweden)

    Wu YB

    2016-01-01

    Full Text Available Yinbing Wu,1,2 Mingxin Pan,1 Shuzhong Cui,2 Mingchen Ba,2 Zulong Chen,2 Qiang Ruan2 1Second Department of Hepatobiliary Surgery, Zhujiang Hospital, Southern Medical University, 2Treatment Center of Body Cavitary Thermo-Perfusion, Cancer Hospital of Guangzhou Medical University, Guangzhou Medical University, Guangzhou, People’s Republic of China Background: This study aimed to evaluate the efficacy and safety of ultrasound-guided continuous hyperthermic intraperitoneal perfusion chemotherapy (CHIPC for the treatment of malignant ascites (MA. Methods: Between July 2011 and June 2013, 36 MA patients were prospectively and consecutively hospitalized for three cycles of elective CHIPC under ultrasound guidance, maintained at a constant flow rate of 400–600 mL/min normal saline containing 5-fluorouracil plus mitomycin or carboplatin and at a constant temperature of 43°C±0.2°C, for 90 minutes. Main outcome measures were ascites resolution, Karnofsky performance status (KPS, and serum tumor biomarkers at 2 weeks after the last cycle of CHIPC. All the patients underwent uneventful CHIPC as scheduled, and vital signs remained stable over CHIPC. Results: At 2 weeks after the last cycle of CHIPC, MA completely and partially resolved in 26 (72.2% patients and eight (22.2% patients, respectively; mean KPS score increased from pretreatment 61±9 to posttreatment 76±9 (P<0.001, and serum carcinoembryonic antigen and carbohydrate antigens 12-5 and 19-9 significantly decreased (all P<0.01. Conclusion: The current study indicated that ultrasound-guided CHIPC is an effective and safe palliative treatment modality for MA with respect to MA resolution, patient’s general well-being, and systemic disease control. The long-term benefit of CHIPC on overall survival remains to be investigated in MA patients. Keywords: continuous hyperthermic intraperitoneal perfusion chemotherapy, malignant ascites, peritoneal carcinomatosis, ultrasound guidance, safety

  16. Baicalein attenuates the quorum sensing-controlled virulence factors of Pseudomonas aeruginosa and relieves the inflammatory response in P. aeruginosa-infected macrophages by downregulating the MAPK and NFκB signal-transduction pathways

    Directory of Open Access Journals (Sweden)

    Luo J

    2016-01-01

    Full Text Available Jing Luo,* Jin-liang Kong,* Bi-ying Dong, Hong Huang, Ke Wang, Li-hong Wu, Chang-chun Hou, Yue Liang, Bing Li, Yi-qiang Chen Department of Respiratory Disease, First Affiliated Hospital of Guangxi Medical University, Nanning, People’s Republic of China *These authors contributed equally to this work Abstract: Burgeoning antibiotic resistance and unfavorable outcomes of inflammatory injury after Pseudomonas aeruginosa infection have necessitated the development of novel agents that not only target quorum sensing (QS but also combat inflammatory injury with the least risk of resistance. This study aimed to assess the anti-QS and anti-inflammatory activities of baicalein, a traditional herbal medicine that is widely used in the People’s Republic of China, against P. aeruginosa infection. We found that subminimum inhibitory concentrations of baicalein efficiently interfered with the QS-signaling pathway of P. aeruginosa via downregulation of the transcription of QS-regulated genes and the translation of QS-signaling molecules. This interference resulted in the global attenuation of QS-controlled virulence factors, such as motility and biofilm formation, and the secretion into the culture supernatant of extracellular virulence factors, including pyocyanin, LasA protease, LasB elastase, and rhamnolipids. Moreover, we examined the anti-inflammatory activity of baicalein and its mode of action via a P. aeruginosa-infected macrophage model to address its therapeutic effect. Baicalein reduced the P. aeruginosa-induced secretion of the inflammatory cytokines IL-1β, IL-6, IL-8, and TNFα. In addition, baicalein suppressed P. aeruginosa-induced activation of the MAPK and NFκB signal-transduction pathways in cocultured macrophages; this may be the mechanism by which baicalein inhibits the production of proinflammatory cytokines. Therefore, our study demonstrates that baicalein represents a potential treatment for P. aeruginosa infection because it

  17. Comparing root architectural models

    Science.gov (United States)

    Schnepf, Andrea; Javaux, Mathieu; Vanderborght, Jan

    2017-04-01

    Plant roots play an important role in several soil processes (Gregory 2006). Root architecture development determines the sites in soil where roots provide input of carbon and energy and take up water and solutes. However, root architecture is difficult to determine experimentally when grown in opaque soil. Thus, root architectural models have been widely used and been further developed into functional-structural models that are able to simulate the fate of water and solutes in the soil-root system (Dunbabin et al. 2013). Still, a systematic comparison of the different root architectural models is missing. In this work, we focus on discrete root architecture models where roots are described by connected line segments. These models differ (a) in their model concepts, such as the description of distance between branches based on a prescribed distance (inter-nodal distance) or based on a prescribed time interval. Furthermore, these models differ (b) in the implementation of the same concept, such as the time step size, the spatial discretization along the root axes or the way stochasticity of parameters such as root growth direction, growth rate, branch spacing, branching angles are treated. Based on the example of two such different root models, the root growth module of R-SWMS and RootBox, we show the impact of these differences on simulated root architecture and aggregated information computed from this detailed simulation results, taking into account the stochastic nature of those models. References Dunbabin, V.M., Postma, J.A., Schnepf, A., Pagès, L., Javaux, M., Wu, L., Leitner, D., Chen, Y.L., Rengel, Z., Diggle, A.J. Modelling root-soil interactions using three-dimensional models of root growth, architecture and function (2013) Plant and Soil, 372 (1-2), pp. 93 - 124. Gregory (2006) Roots, rhizosphere and soil: the route to a better understanding of soil science? European Journal of Soil Science 57: 2-12.

  18. Sex-Dependent Effects of Cadmium Exposure in Early Life on Gut Microbiota and Fat Accumulation in Mice.

    Science.gov (United States)

    Ba, Qian; Li, Mian; Chen, Peizhan; Huang, Chao; Duan, Xiaohua; Lu, Lijun; Li, Jingquan; Chu, Ruiai; Xie, Dong; Song, Haiyun; Wu, Yongning; Ying, Hao; Jia, Xudong; Wang, Hui

    2017-03-01

    Environmental cadmium, with a high average dietary intake, is a severe public health risk. However, the long-term health implications of environmental exposure to cadmium in different life stages remain unclear. We investigated the effects of early exposure to cadmium, at an environmentally relevant dosage, on adult metabolism and the mechanism of action. We established mouse models with low-dose cadmium (LDC) exposure in early life to examine the long-term metabolic consequences. Intestinal flora measurement by 16S rDNA sequencing, microbial ecological analyses, and fecal microbiota transplant was conducted to explore the potential underlying mechanisms. Early LDC exposure (100 nM) led to fat accumulation in adult male mice. Hepatic genes profiling revealed that fatty acid and lipid metabolic processes were elevated. Gut microbiota were perturbed by LDC to cause diversity reduction and compositional alteration. Time-series studies indicated that the gut flora at early-life stages, especially at 8 weeks, were vulnerable to LDC and that an alteration during this period could contribute to the adult adiposity, even if the microbiota recovered later. The importance of intestinal bacteria in LDC-induced fat accumulation was further confirmed through microbiota transplantation and removal experiments. Moreover, the metabolic effects of LDC were observed only in male, but not female, mice. An environmental dose of cadmium at early stages of life causes gut microbiota alterations, accelerates hepatic lipid metabolism, and leads to life-long metabolic consequences in a sex-dependent manner. These findings provide a better understanding of the health risk of cadmium in the environment. Citation: Ba Q, Li M, Chen P, Huang C, Duan X, Lu L, Li J, Chu R, Xie D, Song H, Wu Y, Ying H, Jia X, Wang H. 2017. Sex-dependent effects of cadmium exposure in early life on gut microbiota and fat accumulation in mice. Environ Health Perspect 125:437-446; http://dx.doi.org/10.1289/EHP360.

  19. 95 % rigtigt eller 100 % forkert?

    DEFF Research Database (Denmark)

    Thorseth, Anders

    2013-01-01

    Når det gælder måling af lys, har måleusikkerhed længe været et mørkt felt. Men nye lyskilder stiller nye krav, og hvis der ikke er styr på måleusikkerheden, er der måske heller ikke styr på målingen. CIE division 2 holdt workshop om emnet i oktober i Slovenien, og DTU Fotonik var med....

  20. Die Wasserstoff-Palladium-Bindung bei Adsorption des Wasserstoffs an den (100)-und (111)-Oberflächen sowie Diffusion und Absorption im Kristallgitter aus der Sicht der SW-Xα-Methode / Investigation of the hydrogen-palladium bond of hydrogen being adsorbed on the (100)- and (111)-surfaces, diffusing and being absorbed in the crystal-lattice using the SW-Xα-method

    Science.gov (United States)

    Fritsche, Hans-Gerhard

    1983-10-01

    SW-Xα-calculations pf PdnH-and Pdn-clusters of Oh -, Td -, C4v -and C3v -symmetry are carried out to investigate the bonding mechanism of hydrogen being chemisorbed at the (100)- and (111)-surfaces, entering the lattice and being absorbed at interstitial sites. Densities of states, local electron densities, spherical electron densities, integral electron charges as well as maps of the main H-Pd bonding orbital are compared in order to characterize the hydrogen-palladium bond.

  1. 專論/以關鍵詞網絡探討動態性知識管理議題/陳良駒;張正宏 | Exploring Dynamic Knowledge Management Research Issues: A Keyword Network Analysis / Liang-Chu Chen; Jeng-Horng Chang

    Directory of Open Access Journals (Sweden)

    陳良駒、張正宏

    2007-10-01

    Full Text Available

    知識管理是企業邁向知識經濟時代的實務顯學,也是學術界近年來持續探討的重要研究議題。然而知識管理的面向是一種多維度的呈現,如何快速而正確的瞭 解知識管理議題的發展,是許多組織知識工作者及學術研究學者努力的目標。許多學者提出知識管理內容的架構及分類,但卻都是屬於一種由上而下的靜態設計。社 會網絡分析是呈現及量測網絡實體成員互動的技術,適合建構關係網絡的動態性。本文嘗試以關鍵詞網絡來分析國內資訊相關系所從事知識管理研究的主題及脈絡, 並透過關鍵詞的連結來建構一套動態性的知識管理研究範疇。研究成果除驗證知識管理學域中的研究重點,更透過網絡關係來連結多樣性的研究構想,進而提供產官 學界更宏觀且動態的知識管理研究建議。

    Knowledge management (KM is an important practice in a corporation and an essential issue that academic scholars intend to explore continuously in the era of knowledge economy. However, KM presents a variety of perspectives that are still undefined for many knowledge workers and academic researchers. Many scholars propose a few categories and frameworks about KM, but a static outcome. Social network analysis (SNA is a method to present and measure the interaction among network entities and it is suitable to construct the dynamic relationship networks. The purpose of this study is to acquire the research issues and contexts of KM within information-related graduate schools based on a keyword network analysis. Moreover, we build a dynamic KM research network through these linkages with keywords. The results of this study confirm the essential research perspectives in a KM domain and suggest a variety of KM research ideas which provide the industries, governments, and academic communities with a macro and dynamic KM research viewpoint.

    頁次:81-94

  2. Zum Vorkommen von Wildbienen und Wespen (Hymenoptera, Aculeata) : auf Magerrasenflächen, Wald- und Wegrändern, verschiedenen Grünlandbereichen der (Nethe-) Flussaue sowie im Siedlungsbereich bei den Ortschaften Ottbergen, Bruchhausen und Amelunxen (Nordrhein-Westfalen, Landkreis Höxter) ; eine erläuterte Liste der nachgewiesenen Wildbienen und Wespen

    OpenAIRE

    Reidt, Jörg von der

    2006-01-01

    Die Bestimmung der gefangenen und präparierten Belegindividuen erfolgte mit einem Stereomikroskop (Binokular) bei ca. 30 bis 60 Vergrößerung. Für die Determination der Bienen und Wespen, insbesondere für einzelne Gattungen der Familie Apidae, ist eine Vielzahl von spezieller Bestimmungsliteratur erforderlich. Zur besseren Übersicht ist die, für die Determination als auch die zur Klärung systematischer und nomenklatorischer Fragen, benutzte Literatur in der nachfolgenden Tabelle aufgeführt....

  3. Response to the comment by C. Kisielowski, H.A. Calderon, F.R. Chen, S. Helveg, J.R. Jinschek, P. Specht, D. Van Dyck on the article "On the influence of the electron dose-rate on the HRTEM image contrast" by J. Barthel, M. Lentzen, A. Thust, Ultramicroscopy 176 (2017) 37-45.

    Science.gov (United States)

    Barthel, Juri; Lentzen, Markus; Thust, Andreas

    2017-08-01

    In a recent article [1] we examined the influence of the applied electron dose rate on the magnitude of the image contrast in high-resolution transmission electron microscopy (HRTEM). We concluded that the magnitude of the image contrast is not substantially affected by the applied electron dose rate. This result is in obvious contradiction to numerous earlier publications by Kisielowski and coworkers [2-7], who commented our recent article due to this contradiction. The present short communication is a response to the comment of Kisielowski and coworkers on our recent article, where we provide additional arguments supporting our initial findings and conclusions on the magnitude of the image contrast in HRTEM. Copyright © 2017 Elsevier B.V. All rights reserved.

  4. Fortschritt als Fraktur im frühen Science Fiction Film. Metaphorologische Überlegungen zu Auf- und Einbrüchen in LE VOYAGE DANS LA LUNE und LE VOYAGE À TRAVERS L`IMPOSSIBLE von G. Méliès

    Directory of Open Access Journals (Sweden)

    Hartmann, Jörg

    2009-09-01

    Full Text Available Fantasies of man travelling into space form a main part of the popular movie genre ‘Science Fiction’. These celluloid visions are not only fantasies of improving transport, they also convey a meaning in a figurative sense. They can be seen as a modern adoption of one of humanities oldest metaphors, ‘life as a sea fare voyage’: the meaning, which was once expressed by this ‘nautical metaphor’, has been transferred and can nowadays be found in films, which show astro-nauts crossing the frontier from known space into the unknown space. In order to conclude on their attitude towards technological progress in the early 20th century, the two oldest space travel movies, Le Voyage dans la Lune (F 1902 and Le Voyage a Travers L’Impossible (F 1904 will be analyzed.

  5. 專論/品質保證應用在圖書資訊學數位課程發展之行動研究/王梅玲、陳巧倫(Mei-Ling Wang; Ciao-Lun Chen

    Directory of Open Access Journals (Sweden)

    王梅玲、陳巧倫 Mei-Ling Wang; Ciao-Lun Chen

    2009-10-01

    Full Text Available 網際網路促成數位學習發展,如今成為高等教育潮流,美國10 餘所圖書資訊學研究所提供數位碩士學程已培養許多圖書館專業人才。我國公共圖書館與學校圖書館普遍存在許多工作人員未受過專業教育的問題,因此圖書資訊學數位課程與學程長久以來受到期待。本論文基於數位學習品質保證原理,以行動研究方法,探討圖書資訊學數位課程的設計與發展。研究目的包括:(1)探討數位學習品質保證原理與機制;(2)運用品質保證規範以設計數位課程;(3)以行動研究發展圖書資訊學數位學習專班與數位課程;(4)檢討品質保證對數位課程發展之成效。本研究於2007年至2008 年間研發六門數位課程,包括知識組織與資訊取用、研究方法、學校圖書館管理、檔案學研究、圖書資訊學研討與數位圖書館等課程,利用行動研究,規劃與發展課程,並藉課程評鑑回饋修正,最後總結並提出建議。 E-learning is flourishing in higher education due to its ability to lift time and place restrictions from teaching and learning. Because many library staff has not received professional education, more E-learning curricula and programs by Library and Information Science schools is something that many libraries in Taiwan look forward to. Facing demand for E-learning from library staff, the Graduate Institute of Library, Information and Archival Studies (LIAS at National Cheng-Chi University undertook an experimental curriculum project. The purpose of this study was to develop an E-learning master’s program with six E-learning curricula for library staff and instructors in senior high schools in accordance with quality assurance mechanism .The study was conducted as action research with five stages as follows: (a describing the problem and its focus; (b exploring some action options for the problem; (cseeking collaborative partners and discussing; (dundertaking action options: the five lecturers of the LIAS planned and developed six E-learning courses with web-based learning systems; (f evaluation and feedback: six courses were modified according to student learning outcome assessments and course reviews. In 2008, six E-learning courses were developed and program and curricular accreditation was applied for from the Ministry of Education. Six e-learning courses were Information, Organization and Access; Research Methodology; School Library Management; Seminar on Archival Studies; Seminar on Library and Information Science; and Digital Libraries. In addition to describing the planning and implementation of the curriculum, the article also reviews the effectiveness of E-learning teaching and learning, as well as offering final conclusions and recommendations. 頁次:54-65

  6. THE LITHOSPHERIC MAGNETIC FIELD ALONG THE NISHAN-GUYANG PROFILE, CHINA 6 datesYuan Jiehao1; Gu Zuowen1; Chen Bin1; Xu Rugang2; Wang Lie2; Wang Can1 1. Institute of Geophysics, China Earthquake Administration(IGP CEA), yjh810405@163.com 2. Anhui Earthquake Administration

    Science.gov (United States)

    Yuan, J.

    2014-12-01

    In order to research the lithospheric magnetic field and the magnetization structure, the geomagnetic field was surveyed along the Nishan-Guyang profile with 900 km long in the Neimenggu and Shanxi provinces in China. The distance between the adjacent geomagnetic sites is about 7 km along the profile. The geomagnetic data were analyzed, and the lithospheric magnetic field was obtained. Using the upward continuation method, the geomagnetic anomalies in different depths were obtained: the basement anomaly, the upper crust anomaly and the superficial anomaly. Basing on these geomagnetic anomalies, the magnetization structure was obtained by using the software of the ModelVision 11.0. The preliminary results show: (1) The geomagnetic anomalies have good relationship with the local geological structure. (2) The magnetization structure is related to the depth variation of the Curie interface, the values of the magnetic susceptibility, the seismic activity and the tectonic block.

  7. Web Usability Policies/Standards/Guidelines Do Not Influence Practices at ARL Academic Libraries. A Review of: Chen, Yu‐Hui, Carol Anne Germain and Huahai Yang. “An Exploration into the Practices of Library Web Usability in ARL Academic Libraries.” Journal of the American Society for Information Science and Technology 60.5 (2009: 953‐68.

    Directory of Open Access Journals (Sweden)

    Shandra Protzko

    2009-12-01

    Full Text Available Objective – To survey the current status of Web usability Policies/Standards/Guidelines (PSGs found in academic libraries of the Association of Research Libraries (ARL. Researchers sought to investigate whether PSGs are in place, the levels of difficulty surrounding implementation, the impact of PSGs on design, testing, and resource allocation, and the relationship between ARL ranking and usability practice or PSGs.Design – Survey.Setting – North America.Subjects – Academic libraries of the ARL.Methods – An 18‐question survey consisting of multiple choice, Likert scale, and open‐ended questions was sent to all 113 ARL libraries in November 2007. Survey recipients were selected as the person in charge of Web site usability by visiting library Web sites and phone inquiry. The survey was concluded in January 2008 with a response rate of 74% (84 institutions. The researchers used t‐test to detect any difference in ARL library ranking between libraries with and without PSGs. Pair‐wise t‐tests were conducted to identify gaps in difficulty implementing PSGs. In addition, they used Pearson’s Correlation to investigate any significant correlations between variables such as ARL rank and resource allocation.Main Results – Of the 84 respondents, 34 (40% have general library Web PSGs and 25 (30% have specific usability PSGs; 41 (49% have at least one type of in‐library PSG. Of the 43 (51% libraries that do not have PSGs, 30 (36% are at universities with institutional Web usability PSGs; 26 (87% follow those guidelines. There was no statistically significant relationship between ARL ranking and PSG status (see Table 1. The authors asked about difficulty in implementing PSGs. Of the 32 libraries responding to a question about general library Web PSGs, most had slight or moderate difficulty. Twenty‐three libraries with specific usability PSGs identified difficulty levels; some had no difficulty, but a majority had moderate difficulty. For the 26 libraries using institutional Web usability PSGs, most had no or slight difficulty. Pair‐wise t‐tests showed that library Web usability PSGs were significantly more difficult to implement than university Web usability PSGs. Enforcement/agreement issues were reported as the primary difficulty in implementing in‐library PSGs. Technical issues and ambiguity were obstacles at the institutional level. More than half of the 84 libraries have Web advisory committees and about one third have usability committees or Web usability subcommittees. Several libraries answered that they have none of these committees, but indicated that they have some sort of ad hoc committee or user study group to address usability issues. Of the 84 respondents, 71 (85% have conducted usability testing. Sixty‐two libraries (73.8% rated usability testing as important, very important, or extremely important: the rate given for the importance of usability testing did not correlate with ARL ranking. Cited most often in open ended questioningwere the importance of iterative testing, library wide buy‐in, and staff and resource availability. Main web pages were tested most frequently. Fifty‐three libraries (74.6% tested their lower level pages at least once. OPACs were tested the least often. The amount of testing was impacted neither by the existence of library Web PSGs nor usability PSGs. The top two testing methods were in‐person observation and think aloud protocol.Of the 84 libraries, 24 (28% reported having staff dedicated to Web usability issues; twenty full‐time staff and four part‐time staff. There was a weak association between ARL ranking and hours worked by dedicated staff; no association existed for regular staff who take on Web responsibilities. Fifty‐one (60% of libraries had regular staff whose duties included Web usability; forty‐six full‐time and five part‐time. Training did not correlate to amount of testing methods used. There was a weak link between ALR ranking and availability of resources and, the authors showed, more testing was done as resources increased. In response to a query about future Web usability plans, the focus was on usability testing and site redesign, with only three libraries planning to refine or establish usability PSGs.Conclusion – The authors hypothesized that “web usability PSGs would influence usability practice within libraries and other institutions” (953. The data show that PSGs do not influence practices. The authors conclude that there is no significant relationship between PSGs and testing practices or PSGs and the availability of resources. Likewise, ARL ranking had no effect on the establishment of usability PSGs. Most libraries are conducting usability testing, and there was a weak link between ARL ranking and availability of testing resources. Highlighted in the open‐ended questions is the lack of usability expertise among stakeholders. Workload, inadequate human resources, and lack of organizational cohesion are also cited as barriers to the adoption of Web usability PSGs. The authors speculate that Web professionals likely use their own working knowledge and internalized guidelines without having formal documentation. The authors further speculate that the difficulty related to creating mental models that adequately represent library tasks may hinder the use of formal usability PSGs. Additionally, libraries may not regard the lack of usability PSGs as a liability, especially in light of the lack of government mandates or standards. The authors recommend educational efforts for key players on the value of Web usability, support for hiring dedicated staff, and formal documentation to guide design practice. The authors plan to compare the collected PSGs in an upcoming project. Future research could focus on non‐ARL libraries, the relationship between PSGs and user experience, and Content Management System (CMS usability characteristics.

  8. 實徵研究/國小教師以CREATER模式推動資訊素養創新課程之歷程/謝佩紋;林菁|The Process of Elementary School Teachers Implementing an Innovation Curriculum of Information Literacy with CREATER Model/Pei-Wen Hsieh; Lin Ching Chen

    Directory of Open Access Journals (Sweden)

    謝佩紋、林菁 Pei-Wen Hsieh; Lin Ching Chen

    2009-04-01

    Full Text Available 本研究旨在探究國小教師推動資訊素養創新課程的歷程,並以CREATER革新模式的七個階段為架構,深入瞭解教師作為創新推動者在每個階段的經歷及結果,以提供有意推動資訊素養理念或其它創新的教育工作者參考。本研究採個案研究,以南部一所國小為研究個案,研究時間歷時一年半,透過觀察、訪談、文件分析等方法進行資料的蒐集。研究結果發現,國小教師推動資訊素養課程的歷程大致與CREATER模式的七個階段相符,但「關心」、「連結」與「檢視」階段並無明顯次序,教師以組織內成員的角色推動創新,能有效地將創新理念化為行動,但行動能否持續及發揮效果,還有賴團隊組成的完整性、教師的持續更新力及組織內掌握實權者的支持與參與。The purpose of this study was to explore the change process of implementing an information literacy curriculum by elementary school teachers. Based on the CREATER model, this study investigated the teachers’ experiences as change agents in each stage of the process. The research results could provide guidelines for educators who are devoted to promote the information literacy or other innovations. The method of case study was used to design this study. The subjects of this study were the teachers who voluntarily implemented the information literacy curriculum in an elementary school in the southern part of Taiwan. The methods for collecting research data were observations, interviews, and document analyses. The research results showed that the change process of implementing the information literacy curriculum corresponded to the seven stages of the CREATER model. However, the stages of “care,” “relate,” and “examine,” did not obviously happen in sequence. As members of the organization, the teachers could transform effectively the innovative concept into an action, but whether the innovation could be persistent depended on team relationships, teachers’ self-renewal capacity, and approvals and participation of the leaders who really managed the organization.頁次:70-89

  9. Less is more: standard warm-up causes fatigue and less warm-up permits greater cycling power output.

    Science.gov (United States)

    Tomaras, Elias K; MacIntosh, Brian R

    2011-07-01

    The traditional warm-up (WU) used by athletes to prepare for a sprint track cycling event involves a general WU followed by a series of brief sprints lasting ≥ 50 min in total. A WU of this duration and intensity could cause significant fatigue and impair subsequent performance. The purpose of this research was to compare a traditional WU with an experimental WU and examine the consequences of traditional and experimental WU on the 30-s Wingate test and electrically elicited twitch contractions. The traditional WU began with 20 min of cycling with a gradual intensity increase from 60% to 95% of maximal heart rate; then four sprints were performed at 8-min intervals. The experimental WU was shorter with less high-intensity exercise: intensity increased from 60% to 70% of maximal heart rate over 15 min; then just one sprint was performed. The Wingate test was conducted with a 1-min lead-in at 80% of optimal cadence followed by a Wingate test at optimal cadence. Peak active twitch torque was significantly lower after the traditional than experimental WU (86.5 ± 3.3% vs. 94.6 ± 2.4%, P track cyclist's WU results in significant fatigue, which corresponds with impaired peak power output. A shorter and lower-intensity WU permits a better performance.

  10. Real-world hospital costs for nonchemotherapy drugs and nondrug care associated with platinum-based doublets in the first-line setting for advanced nonsquamous non-small-cell lung cancer in Chinese patients: a retrospective cohort study

    Directory of Open Access Journals (Sweden)

    Chen JH

    2016-04-01

    Full Text Available Jianhua Chen,1 Shengqi Wu,2 Chenping Hu,3 Yicheng Yang,4 Narayan Rajan,5 Yun Chen,4 Canjuan Yang,6 Jianfeng Li,6 Wendong Chen7 1Department of Medical Oncology, 2Department of Research and Education, Hunan Province Tumor Hospital, 3Department of Respiratory, Xiangya Hospital, Central South University, Changsha, Hunan, 4Lilly Suzhou Pharmaceutical Co., Ltd. Shanghai Branch, Shanghai, People's Republic of China; 5Global Health Outcomes Research, Eli Lilly and Co, Indianapolis, IN, USA; 6Division of Health Outcome Research, Normin Health Changsha Representative Office, Changsha, Hunan, People's Republic of China; 7Normin Health, Toronto, ON, Canada Objective: The objective of this study was to compare hospital costs per treatment cycle (HCTC for nonchemotherapy drugs and nondrug care associated with platinum-based doublets in the first-line setting for advanced nonsquamous non-small-cell lung cancer (AdvNS-NSCLC in Chinese patients. Methods: Patients receiving platinum-based doublets in the first-line setting for AdvNS-NSCLC from 2010 to 2012 in two Chinese tertiary hospitals were identified to create the retrospective study cohort. Propensity score methods were used to create matched treatment groups for head-to-head comparisons on HCTC between pemetrexed–platinum and other platinum-based doublets. Multiple linear regression analyses were performed to rank studied platinum-based doublets for their associations with the log10 scale of HCTC for nonchemotherapy drugs and nondrug care. Results: Propensity score methods created matched treatment groups for pemetrexed–platinum versus docetaxel–platinum (61 pairs, paclitaxel–platinum (39 pairs, gemcitabine–platinum (93 pairs, and vinorelbine–platinum (73 pairs, respectively. Even though the log10 scale of HCTC for nonchemotherapy drugs and nondrug care associated with pemetrexed–platinum was ranked lowest in all patients (coefficient –0.174, P=0.015, which included patients experiencing

  11. PREFACE: Dynamic crossover phenomena in water and other glass-forming liquids Dynamic crossover phenomena in water and other glass-forming liquids

    Science.gov (United States)

    Chen, Sow-Hsin; Baglioni, Piero

    2012-02-01

    protein hydration water Francesco Mallamace, Carmelo Corsaro, Piero Baglioni, Emiliano Fratini and Sow-Hsin Chen Common features in the microscopic dynamics of hydration water on organic and inorganic surfacesE Mamontov, H O'Neill, Q Zhang, W Wang and D J Wesolowski Water dynamics as affected by interaction with biomolecules and change of thermodynamic state: a neutron scattering studyA Orecchini, A Paciaroni, C Petrillo, F Sebastiani, A De Francesco and F Sacchetti Temperature dependence of structure and density for D2O confined in MCM-41-SWilliam A Kamitakahara, Antonio Faraone, Kao-Hsiang Liu and Chung-Yuan Mou Density profile of water confined in cylindrical pores in MCM-41 silicaAlan K Soper Dynamic crossover in hydration water of curing cement paste: the effect of superplasticizerHua Li, Wei-Shan Chiang, Emiliano Fratini, Francesca Ridi, Francesco Bausi, Piero Baglioni, Madhu Tyagi and Sow-Hsin Chen Water confined in MCM-41: a mode coupling theory analysisP Gallo, M Rovere and S-H Chen Computer simulations of dynamic crossover phenomena in nanoconfined waterG B Suffritti, P Demontis, J Gulín-Gonźlez and M Masia Hydrophobic nanoconfinement suppresses fluctuations in supercooled waterE G Strekalova, M G Mazza, H E Stanley and G Franzese Other glass-forming liquids Quasi-elastic neutron scattering studies of the slow dynamics of supercooled and glassy aspirinYang Zhang, Madhusudan Tyagi, Eugene Mamontov and Sow-Hsin Chen Colloids Phase diagram of trivalent and pentavalent patchy particlesFlavio Romano, Eduardo Sanz, Piero Tartaglia and Francesco Sciortino Distinguishing the monomer to cluster phase transition in concentrated lysozyme solutions by studying the temperature dependence of the short-time dynamicsPéter Falus, Lionel Porcar, Emiliano Fratini, Wei-Ren Chen, Antonio Faraone, Kunlun Hong, Piero Baglioni and Yun Liu Contrast variation in spin-echo small angle neutron scatteringXin Li, Bin Wu, Yun Liu, Roger Pynn, Chwen-Yang Shew, Gregory S Smith, Kenneth W

  12. Development of genomic SSR and potential EST-SSR markers in ...

    African Journals Online (AJOL)

    PRECIOUS

    2009-11-16

    SSR markers in Bupleurum chinense DC. Chun Sui, Jian-He Wei*, Shi-Lin Chen, Huai-Qiong Chen and Cheng-Min Yang. Institute of Medicinal Plant Development (IMPLAD), Chinese Academy of Medical Sciences (CAMS) and ...

  13. Anbautelegramm Saatwicke (Vicia sativa L.)

    OpenAIRE

    Böhm, Herwart; Weissmann, Elmar

    2013-01-01

    Für den Anbau von Saatwicken werden in einem kurzgefassten Anbautelegramm die Stärken und Schwächen sowie grundlegende Kennwerte zu Standortansprüchen, Aussaat, Unkrautregulierung, Nährstoffbedarf und Schaderregern beschrieben.

  14. Prevalence and associated factors of late HIV diagnosis in north ...

    African Journals Online (AJOL)

    User

    This study aimed to determine the prevalence and associated factors .... a recent study done in eastern part of Tanzania by Mhozya and colleagues (Mhozya, .... Twu SJ, Chen KT, Lin CC, Huang LY, Chen MY, Hwang JS, Wang JD and.

  15. Reduction of the Bethe–Salpeter wave function: Fermion–scalar ...

    Indian Academy of Sciences (India)

    Author Affiliations. Chen Chong1 Chen Jiao-Kai2. School of Mathematical Sciences, University of Electronic Science and Technology of China, Chengdu 611731, China; School of Physics and Information Science, Shanxi Normal University, Linfen 041004, China ...

  16. Finite groups with the set of the number of subgroups of possible ...

    Indian Academy of Sciences (India)

    Author Affiliations. Yanheng Chen1 2 Guiyun Chen1. School of Mathematics and Statistics, Southwest University, Chongqing 400715, People's Republic of China; School of Mathematics and Statistics, Chongqing Three Gorges University, Chongqing 404100, People's Republic of China ...

  17. Characterization of PGL (2, p) by its order and one conjugacy class ...

    Indian Academy of Sciences (India)

    Author Affiliations. Yanheng Chen1 2 Guiyun Chen1. School of Mathematics and Statistics, Southwest University, Chongqing 400715, People's Republic of China; School of Mathematics and Statistics, Chongqing Three Gorges University, Chongqing 404100, People's Republic of China ...

  18. Low-Loss Materials for Josephson Qubits

    Science.gov (United States)

    2014-10-09

    Campbell, Y. Chen, Z. Chen, B. Chiaro, A. Dunsworth, I.-C. Hoi, E. Jeffrey, C. Neill , P. J. J. O’Malley, J. Mutus, C. Quintana, P. Roushan, D. Sank, J...Mutus, Peter O’Malley, Charles Neill , Pedram Roushan, Daniel Sank, Amit Vainsencher, James Wenner, Theodore White, Andrew Cleland, John Martinis...Kelly, A. Megrant, A. Veitia, D. Sank, E. Jeffrey, T. White, J. Mutus, A. Fowler, B. Campbell, Y. Chen, Z. Chen, B. Chiaro, A. Dunsworth, C. Neill , P

  19. PREFACE: The 15th International Conference on X-ray Absorption Fine Structure (XAFS15)

    Science.gov (United States)

    Wu, Z. Y.

    2013-04-01

    Committees and Staff Chair of the Conference Ziyu Wu International Advisory Committee Adam Hitchcock, Canada Adriano Filipponi, Italy Alain Manceau, France Alexander Soldatov, Russia Andrea Di Cicco, Italy Britt Hedman, USA Bruce Bunker, USA Calogero R. Natoli, Italy Christopher T. Chantler, Australia Frank M. F. De Groot, Netherlands Hiroyuki Oyanagi, Japan Ingolf Lindau, USA J. Mustre de Leon, México James E Penner-Hahn, USA Joaquin Garcia Ruiz, Spain John Evans, UK John J. Rehr, USA Kiyotaka Asakura, Japan Majed Chergui, Switzerland Mark Newton, UK Shiqiang Wei, P. R. China Tsun-Kong Sham, Canada Ziyu Wu, P. R. China International Program Committee Antonio Bianconi, Italy Augusto Marcelli, Italy Emad Flear Aziz, Germany Jinghua Guo, USA Joly Yves, France Masaharu Nomura, Japan Maurizio Benfatto, Italy Pieter Glatzel, France Shiqiang Wei, China Tiandou Hu, China Toshihiko Yokoyama, Japan Way-Faung Pong, Taiwan Xinyi Zhang, China Yi Xie, China Yuying Huang, China Zhonghua Wu, China Ziyu Wu, China Local Organizing Committee Bo He Fengchun Hu Haifeng Zhao Jing Zhang Meijuan Yu Qin Yu Shuo Zhang Wangsheng Chu Wei He Wei Xu Wensheng Yan Xiaomei Gong Xing Chen Yang Zou Yi Xia Zheng Jiang Zhi Xie Zhihu Sun Zhiyun Pan Additional Staff Chengxun Liu

  20. ICCG-10: International Conference on Crystal Growth (10th) Held in San Diego, California on August 16-21, 1992. Oral Presentation Abstracts.

    Science.gov (United States)

    1992-10-01

    CRYSTAL GROWTH OF YVO4 USING THE LHPG TECHNIQUE S. Erdei and F. W. Anger Materials Research Laboratory The Pennsylvania State University, University Park...Bauser- 118 G. Chen- 192 Y. Einav - 135 Roger F. Belt- 9, 105 Huanchu Chen- 12 S. Endo- 188 H. Bender- 121 Men-Chee Chen- 161 S. Erdei - 112 P. Bennema

  1. A Comparison of the Treatment of Cyanide Poisoning in the Cynomolgus Monkey with Sodium Nitrite of 4-Dimethylaminophenol (4-DMAP), with and without Sodium Thiosulfate

    Science.gov (United States)

    1994-02-01

    Chen et al, 1934), amyl nitrite (Pedigo, 1888; Chen et al, 1933; Klimmek et a, 1988 a and b; Paulet, 1954), sodium nitrite (Hug and Marenzi , 1933; Chen...nitrite de sodium et du sulfure de sodium. Comp. Rend. Soc. Biol. Ses FRI. 111, 89-90. Hug, E., and Marenzi , A.D. (1933). Mecanisme de r’action

  2. Etiska principer för nordiskt ansvar

    DEFF Research Database (Denmark)

    Rendtorff, Jacob Dahl

    2012-01-01

    Vilken etik och vilka etiska prin­ci­per kan vara cen­trala för den fram­tida utveck­lingen av de nor­diska väl­färds­sta­terna? Jacob Dahl Rendtorff går grund­li­gen ige­nom fyra grund­läg­gande stöt­te­pe­lare: auto­nomi, vär­dig­het, integri­tet och sårbarhet.......Vilken etik och vilka etiska prin­ci­per kan vara cen­trala för den fram­tida utveck­lingen av de nor­diska väl­färds­sta­terna? Jacob Dahl Rendtorff går grund­li­gen ige­nom fyra grund­läg­gande stöt­te­pe­lare: auto­nomi, vär­dig­het, integri­tet och sårbarhet....

  3. EDITORIAL: Focus on Iron-Based Superconductors FOCUS ON IRON-BASED SUPERCONDUCTORS

    Science.gov (United States)

    Hosono, Hideo; Ren, Zhi-An

    2009-02-01

    -L Drechsler, N Kozlova, M Bartkowiak, J E Hamann-Borrero, G Behr, K Nenkov, H-H Klauss, H Maeter, A Amato, H Luetkens, A Kwadrin, R Khasanov, J Freudenberger, A Köhler, M Knupfer, E Arushanov, H Rosner, B Büchner and L Schultz Low-energy spin dynamics in the antiferromagnetic phase of CaFe2As2 N J Curro, A P Dioguardi, N ApRoberts-Warren, A C Shockley and P Klavins Muon spin rotation study of magnetism and superconductivity in BaFe2-xCoxAs2 and Pr1-xSrxFeAsO C Bernhard, A J Drew, L Schulz, V K Malik, M Rössle, Ch Niedermayer, Th Wolf, G D Varma, G Mu, H-H Wen, H Liu, G Wu and X H Chen Magnetic impurities in the pnictide superconductor Ba1-xKxFe2As2 Sutirtha Mukhopadhyay, Sangwon Oh, A M Mounce, Moohee Lee, W P Halperin, N Ni, S L Bud'ko, P C Canfield, A P Reyes and P L Kuhns Neutron scattering investigation of the magnetic order in single crystalline BaFe2As2 M Kofu, Y Qiu, Wei Bao, S-H Lee, S Chang, T Wu, G Wu and X H Chen An NMR study on the F-doping evolution of the iron oxypnictide LaFeAs(O1-xFx) Y Nakai, S Kitagawa, K Ishida, Y Kamihara, M Hirano and H Hosono The peculiar physical properties and phase diagram of BaFe2-xCoxAs2 single crystals X F Wang, T Wu, G Wu, R H Liu, H Chen, Y L Xie and X H Chen Synthesis of LnFeAsO1-y superconductors (Ln=La and Nd) using the high-pressure technique Kiichi Miyazawa, Kunihiro Kihou, Motoyuki Ishikado, Parasharam M Shirage, Chul-Ho Lee, Nao Takeshita, Hiroshi Eisaki, Hijiri Kito and Akira Iyo Correlation effects in the iron pnictides Qimiao Si, Elihu Abrahams, Jianhui Dai and Jian-Xin Zhu Competition/coexisitence of magnetism and superconductivity in iron pnictides probed by muon spin rotation Soshi Takeshita and Ryosuke Kadono Impurity-induced in-gap state and Tc in sign-reversing s-wave superconductors: analysis of iron oxypnictide superconductors Yuko Senga and Hiroshi Kontani Intrinsic magnetic properties of the superconductor NdFeAsO0.9F0.1 from local and global measurements R Prozorov, M E Tillman, E D Mun and P C Canfield

  4. The Effects of Different Warm-up Volumes on the 100-m Swimming Performance: A Randomized Crossover Study.

    Science.gov (United States)

    Neiva, Henrique P; Marques, Mário C; Barbosa, Tiago M; Izquierdo, Mikel; Viana, João L; Teixeira, Ana M; Marinho, Daniel A

    2015-11-01

    The aim of this study was to compare the effect of 3 different warm-up (WU) volumes on 100-m swimming performance. Eleven male swimmers at the national level completed 3 time trials of 100-m freestyle on separate days and after a standard WU, a short WU (SWU), or a long WU (LWU) in a randomized sequence. All of them replicated some usual sets and drills, and the WU totaled 1,200 m, the SWU totaled 600 m, and the LWU totaled 1,800 m. The swimmers were faster after the WU (59.29 seconds; confidence interval [CI] 95%, 57.98-60.61) and after the SWU (59.38 seconds; CI 95%, 57.92-60.84) compared with the LWU (60.18 seconds; CI 95%, 58.53-61.83). The second 50-m lap after the WU was performed with a higher stroke length (effect size [ES] = 0.77), stroke index (ES = 1.26), and propelling efficiency (ES = 0.78) than that after the SWU. Both WU and SWU resulted in higher pretrial values of blood lactate concentrations [La] compared with LWU (ES = 1.58 and 0.74, respectively), and the testosterone:cortisol levels were increased in WU compared with LWU (ES = 0.86). In addition, the trial after WU caused higher [La] (ES ≥ 0.68) and testosterone:cortisol values compared with the LWU (ES = 0.93). These results suggest that an LWU could impair 100-m freestyle performance. The swimmers showed higher efficiency during the race after a 1200-m WU, suggesting a favorable situation. It highlighted the importance of the [La] and hormonal responses to each particular WU, possibly influencing performance and biomechanical responses during a 100-m race.

  5. China Report, Science & Technology

    Science.gov (United States)

    1987-04-30

    Contracting System Examined (Wang Shengqiao; KEXUEXUE YU KEXUE JISHU GUANLI, No 1, Jan 87) 3 Wu Wushu Discusses New Scientific, Technical Legislation...research units and must not impose uniformity on them across the board. 12581 CSO: 4008/2074 10 NATIONAL DEVELOPMENTS WU WUSHU DISCUSSES NEW...and Technical Legislation Research Work Conference, State Science and Technology Commission Secretary Wu Wushu [0702 2976 2885] made a request about

  6. Acta Aerodynamica Sinica,

    Science.gov (United States)

    1986-11-03

    Xttack; by Wang Zixing and Wu Genxing .............................. 110’) On the Investigation of Separated Flow in the lase,-by Bian Yinqui and Dong...1984). 109 Effect of Winglet on Spatial Vortex of a Solid in Rotation at /49 High Angle of Attack Wang Zixing and Wu Genxing (Nanjing Aeronautical...attract the separation vortex of the slender body. 120 References [1] Wu Genxing and Wang Zixing, Symposium of China Society of Mechanics on "Flow

  7. Abstracts from the 15th International Myopia Conference

    Directory of Open Access Journals (Sweden)

    Alexandra Benavente-Perez

    2016-11-01

    Full Text Available Table of contents O1 Changes in peripheral refraction associated with decreased ocular axial growth rate in marmosets Alexandra Benavente-Perez, Ann Nour, Tobin Ansel, Kathleen Abarr, Luying Yan, Keisha Roden, David Troilo O2 PPARα activation suppresses myopia development by increasing scleral collagen synthesis--a new drug target to suppress myopia development Chanyi Lu, Miaozhen Pan, Min Zheng, Jia Qu, Xiangtian Zhou O3 Evidence and possibilities for local ocular growth regulating signal pathways Christine F Wildsoet O4 Myopia researches at Eye Hospital of Wenzhou Medical University Fan Lu, Xiangtian Zhou, Jie Chen, Jinhua Bao, Liang Hu, Qinmei Wang, Zibing Jin, Jia Qu O5 Color, temporal contrast and myopia Frances Rucker, Stephanie Britton, Stephan Hanowsky, Molly Spatcher O6 The impact of atropine usage on visual function and reading performance in myopic school children in Taiwan Hui-Ying Kuo, Ching-Hsiu Ke, I-Hsin Kuo, Chien-Chun Peng, Han-Yin Sun O7 Increased time outdoors prevents the onset of myopia: evidence from randomised clinical trials Ian G Morgan O8 Environmental risk factors and gene-environment interactions for myopia in the ALSPAC cohort Jeremy A. Guggenheim, Rupal L. Shah, Cathy Williams O9 Retinal metabolic profiling identifies declines in FP receptor-linked signaling as contributors to form-deprived myopic development in guinea pigs Jinglei Yang, Peter S. Reinach, Sen Zhang, Miaozhen Pan, Wenfeng Sun, Bo Liu, Xiangtian Zhou O10 The study of peripheral refraction in moderate and high myopes after one month of wearing orthokeratology lens Jun Jiang, Haoran Wu, Fan Lu O11 Axial length of school children around the earth’s equatorial area and factors affecting the axial length Kazuo Tsubota, Hiroko Ozawa, Hidemasa Torii, Shigemasa Takamizawa, Toshihide Kurihara, Kazuno Negishi O12 Processing of defocus in the chicken retina by retinal ganglion cells Klaus Graef, Daniel Rathbun, Frank Schaeffel O13 Blue SAD light protects

  8. Physiological and Psychophysical Responses to Listening to Music during Warm-Up and Circuit-Type Resistance Exercise in Strength Trained Men

    OpenAIRE

    Hamid Arazi; Abbas Asadi; Morteza Purabed

    2015-01-01

    The purpose of this study was to assess the effects of listening to music during warm-up and resistance exercise on physiological (heart rate and blood pressure) and psychophysical (rating of perceived exertion) responses in trained athletes. Twelve strength trained male participants performed warm-up and resistance exercise without music (WU+RE without M), warm-up and resistance exercise with music (WU+RE with M), WU with M and RE without M, and WU without M and RE with M, with 48 hours spac...

  9. JPRS Report China

    Science.gov (United States)

    1990-04-13

    Grain Problems; Tianjin Port Handles More Exports; Inner Mongolia Personnel Reshuffles Noted; Origin of Taiwan Independence Movement Analyzed; Publisher Wu Feng-shan Discusses Political Trends; and others.

  10. Improving Undergraduates' Argumentative Group Essay Writing through Self-Assessment

    National Research Council Canada - National Science Library

    Fung, Yong Mei; Mei, Hooi Chee

    2015-01-01

    When writing an argumentative essay, writers develop and evaluate arguments to embody, initiate, or simulate various kinds of interpersonal and textual interaction for reader consideration (Wu & Allison, 2003...

  11. 實徵研究/基於自動查詢語句擴展之主題地圖智慧型新聞搜尋引擎/陳志銘;張美華;邱偉嘉 │ An Intelligent News Search Engine with Topic Map User Interface Based on Automatic Query Expansion / Chih-Ming Chen; Mei-Hua Chang; Wei-Chia Chiu

    Directory of Open Access Journals (Sweden)

    陳志銘、張美華、邱偉嘉 Chih-Ming Chen; Mei-Hua Chang; Wei-Chia Chiu

    2008-10-01

    Full Text Available 近年來快速發展的新聞網站衍生使用者對於資訊查詢的強烈需求,而目前許多新聞網站(例如:Google News可以自動針對網際網路的新聞進行新聞事件的自動分類,以提供讀者相���新聞事件的聚集資訊,也提供以關鍵字進行新聞查詢的功能,但是卻無法提供整 個相關新聞事件發展脈絡的查詢及依據主題相關之新聞地圖的呈現機制。本研究利用Google News可以自動將新聞事件分類的特性,進一步利用改良式霍普菲爾類神經網路(Modified Hopfield Neural Networks, MHNN自動歸納產生新聞查詢語句知識本體(ontology,並依據所產生之新聞查詢語句知識本體,提出了一個可以依據使用者感興趣新聞類別來做新 聞事件的擴展查詢(query expansion機制,以強化新聞搜尋的效能。此外,藉由主題地圖(topic maps之方式提供有別於傳統新聞呈現方式給使用者瀏覽閱讀,可以將新聞查詢結果依據時間標記及主題關聯呈現,讓使用者能更清楚地掌握整個新聞主題的發 展脈絡。With the rapid development of the computer and Internet techniques, the Internet appears some news aggregator sites containing a large number of news articles, thus leading to advanced information retrieval requirements. Particularly, some news sites, such as Google news, provide automatically classified news information and keyword based search mechanism to readers for retrieving user-interested news events. However, most news sites do not provide currently to retrieve the developing clues of a news event and display the search results by the topic map with visualization user interface. Therefore, this study presents a novel news search engine with automatic user query expansion mechanism and a friendly topic map user interface based on the automatic generation scheme of news ontology constructed by Modified Hopfield Neural Networks. The experimental results indicate that the proposed query expansion mechanism based on the generated news ontology can efficiently help users to retrieve the user-interested news events. Meanwhile, the providing topic map of news events ranked by time stamp also provides benefits in terms of observing the developing context of a news event.頁次:19-41

  12. Beneficial effects of prolonged blood pressure control after carotid artery stenting

    Directory of Open Access Journals (Sweden)

    Chang A

    2017-01-01

    Full Text Available Anna Chang,1 Huei-Fong Hung,2 Fang-I Hsieh,3 Wei-Hung Chen,1,4 Hsu-Ling Yeh,1,5 Jiann-Horng Yeh,1,6 Hou-Chang Chiu,1,6 Li-Ming Lien1,4 1Department of Neurology, Shin Kong Wu Ho-Su Memorial Hospital, Taipei, 2Department of Cardiology, Shin Kong Wu Ho-Su Memorial Hospital, Taipei, 3School of Public Health, College of Public Health, Taipei Medical University, Taipei, 4School of Medicine, College of Medicine, Taipei Medical University, Taipei, 5Institute of Public Health, National Yang-Ming University, Taipei, 6School of Medicine, College of Medicine, Fu Jen Catholic University, Taipei, Taiwan Objectives: The main purpose of this study was to investigate whether carotid artery stenting (CAS plus medicine in patients with severe carotid artery stenosis provide a better long-term blood pressure (BP control compared to other medical treatments alone. The other aim was to explore the correlation between post-CAS hypotension within 6 h and long-term BP reductions after CAS. Materials and methods: Patients with severe carotid stenosis were recruited either in the CAS group or in the medication group. BPs and the number of classes of antihypertensive agents were recorded at baseline, 6, and 12 months. Extra BP information was collected at 6 h, 3 days, and 1 month after CAS. Univariate and multivariate linear regressions were performed to test the relationship of BP changes among CAS and medication groups after 6 and 12 months of follow-up. Univariate linear regressions were also used to determine the correlations between the mean or maximal systolic BP (SBP reductions at 6 h and 1 year post-CAS. Results: In total, 72 members in the CAS group and 82 members in the medication group were recruited. Compared with the medication group, patients in the CAS group had greater BP reductions at 6 and 12 months of follow-up after adjusting for confounding factors (13.56 mmHg at 6 months, P=0.0002; 16.98 mmHg at 12 months, P<0.0001. This study also shows significant

  13. Coprescription of Chinese herbal medicine and Western medication among female patients with breast cancer in Taiwan: analysis of national insurance claims

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    Wang BR

    2014-05-01

    Full Text Available Bih-Ru Wang,1,2,* Yuh-Lih Chang,1,2,* Tzeng-Ji Chen,3,4 Jen-Hwey Chiu,5,6 Jing Chong Wu,7 Min-Shan Wu,1 Chia-Lin Chou,1 Yueh-Ching Chou1,2,81Department of Pharmacy, Taipei Veterans General Hospital, Taipei, Taiwan; 2Department and Institute of Pharmacology, National Yang-Ming University, Taipei, Taiwan; 3Department of Family Medicine, Taipei Veterans General Hospital, Taipei, Taiwan; 4Institute of Hospital and Health Care Administration, National Yang-Ming University, Taipei, Taiwan; 5Division of General Surgery, Department of Surgery, Taipei Veterans General Hospital, Taipei, Taiwan; 6Institute of Traditional Medicine, School of Medicine, National Yang-Ming University, Taipei, Taiwan; 7Traditional Medicine Center, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan; 8College of Pharmacy, Taipei Medical University, Taipei, Taiwan*These authors contributed equally to this workBackground: Many female breast cancer (FBC patients take Chinese herbal medicine (CHM and Western medication (WM concurrently in Taiwan. Despite the possibility of interactions between the CHM and WM mentioned in previous studies, the pattern of these coprescriptions in FBC patients remains unclear. Hence, the aim of the present study is to investigate the utilization of coprescriptions of CHM and WM among the FBC patients in Taiwan.Methods: The study was a cross-sectional survey using the sampled cohort in 2009 obtained from the National Health Insurance Research Database in Taiwan. There were 3,507 FBC patients identified from the registry for catastrophic illness patients. Ambulatory visit records, corresponding prescriptions, and the data of beneficiaries belonging to the FBC patients were further extracted. A total of 1,086 FBC patients used CHM at least once. CHM and WM prescribed within any overlapping duration were defined as coprescriptions.Results: There were 868 (80.0% patients simultaneously receiving CHM and WM. A total of 4,927 CHM prescriptions and 6,358 WM

  14. Influence of mycorhization and soil organic matters on lead and antimony transfers to vegetables cultivated in urban gardens: environmental and sanitary consequences

    Science.gov (United States)

    Pierart, Antoine; Braud, Armelle; Lebeau, Thierry; Séjalon-Delmas, Nathalie; Dumat, Camille

    2014-05-01

    . References: Feng, R., Wei, C., Tu, S., Ding, Y., Wang, R., Guo, J., 2013. The uptake and detoxification of antimony by plants: a review. Environ. Exp. Bot. 96, 28-34. Foucault, Y., Lévêque, T., Xiong, T., Schreck, E., Austruy, A., Shahid, M., Dumat, C., 2013. Green manure plants for remediation of soils polluted by metals and metalloids: Ecotoxicity and human bioavailability assessment. Chemosphere 93, 1430-1435. Gu, H.H., Li, F.P., Yu, Q., Gao, Y.Q., Yuan, X.T., 2013. The Roles of Arbuscular Mycorrhizal Fungus Glomus mosseae and Festuca arundinacea in Phytostabilization of Lead/Zinc Tailings. Adv. Mater. Res. 699, 245-250. Lebeau, T., Braud, A., Jézéquel, K., 2008. Performance of bioaugmentation-assisted phytoextraction applied to metal contaminated soils: A review. Environ. Pollut. 153, 497-522. Sharma, A., Sharma, H., 2013. Role of Vesicular Arbuscular Mycorrhiza in the Mycoremediation of Heavy Toxic Metals From Soil. Int J LifeSc Bt Pharm Res 2, 2418-2431. Wu, F., Fu, Z., Liu, B., Mo, C., Chen, B., Corns, W., Liao, H., 2011. Health risk associated with dietary co-exposure to high levels of antimony and arsenic in the world's largest antimony mine area. Sci. Total Environ. 409, 3344-3351. Xiong, T., Austruy, A., Dappe, V., Leveque, T., Sobanska, S., Foucault, Y., Dumat, C., 2013. Phytotoxicity and bioaccessibility of metals for vegetables exposed to atmosphere fine particles in polluted urban areas". Urban Environmental Pollution, Asian Edition, 17-20, Beijing, China.

  15. Cisplatin induces protective autophagy through activation of BECN1 in human bladder cancer cells

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    Lin JF

    2017-05-01

    Full Text Available Ji-Fan Lin,1 Yi-Chia Lin,2 Te-Fu Tsai,2,3 Hung-En Chen,2 Kuang-Yu Chou,2,3 Thomas I-Sheng Hwang2–4 1Central Laboratory, Shin Kong Wu Ho-Su Memorial Hospital, Taipei, 2Division of Urology, School of Medicine, Fu-Jen Catholic University, New Taipei, 3Division of Urology, Department of Surgery, Shin Kong Wu Ho-Su Memorial Hospital, 4Department of Urology, Taipei Medical University, Taipei, Taiwan Purpose: Cisplatin-based chemotherapy is the first line treatment for several cancers including bladder cancer (BC. Autophagy induction has been implied to contribute to cisplatin resistance in ovarian cancer; and a high basal level of autophagy has been demonstrated in human bladder tumors. Therefore, it is reasonable to speculate that autophagy may account for the failure of cisplatin single treatment in BC. This study investigated whether cisplatin induces autophagy and the mechanism involved using human BC cell lines.Materials and methods: Human BC cells (5637 and T24 were used in this study. Cell viability was detected using water soluble tetrazolium-8 reagents. Autophagy induction was detected by monitoring the levels of light chain 3 (LC3-II and p62 by Western blot, LC3-positive puncta formation by immunofluorescence, and direct observation of the autophagolysosome (AL formation by transmission electron microscopy. Inhibitors including bafilomycin A1 (Baf A1, chloroquine (CQ, and shRNA-based lentivirus against autophagy-related genes (ATG7 and ATG12 were utilized. Apoptosis level was detected by caspase 3/7 activity and DNA fragmentation.Results: Cisplatin decreased cell viability and induced apoptosis of 5637 and T24 cells in a dose- and time-dependent manner. The increased LC3-II accumulation, p62 clearance, the number of LC3-positive puncta, and ALs in cisplatin-treated cells suggested that cisplatin indeed induces autophagy. Inhibition of cisplatin-induced autophagy using Baf A1, CQ, or ATG7/ATG12 shRNAs significantly enhanced cytotoxicity of

  16. Autophagy inhibition enhances RAD001-induced cytotoxicity in human bladder cancer cells

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    Lin JF

    2016-04-01

    Full Text Available Ji-Fan Lin,1 Yi-Chia Lin,2,3 Shan-Che Yang,1 Te-Fu Tsai,2,3 Hung-En Chen,2 Kuang-Yu Chou,2,3 Thomas I-Sheng Hwang2–4 1Central Laboratory, Shin-Kong Wu Ho-Su Memorial Hospital, Taipei, Taiwan; 2Division of Urology, Department of Surgery, Shin-Kong Wu Ho-Su Memorial Hospital, Taipei, Taiwan; 3Division of Urology, School of Medicine, Fu-Jen Catholic University, New Taipei City, Taiwan; 4Department of Urology, Taipei Medical University, Taipei, Taiwan Background: Mammalian target of rapamycin (mTOR, involved in PI3K/AKT/mTOR pathway, is known to play a central role in regulating the growth of cancer cells. The PI3K/AKT/mTOR pathway enhances tumor survival and proliferation through suppressing autophagy, which sustains energy homeostasis by collecting and recycling cellular components under stress conditions. Conversely, inhibitors of the mTOR pathway such as RAD001 induce autophagy, leading to promotion of tumor survival and limited antitumor efficacy. We thus hypothesized that the use of autophagy inhibitor in combination with mTOR inhibition improves the cytotoxicity of mTOR inhibitors in bladder cancer.Materials and methods: The cytotoxicity of RT4, 5637, HT1376, and T24 human bladder cancer cells treated with RAD001 alone or combined with autophagy inhibitors (3-methyladenine (3-MA, bafilomycin A1 (Baf A1, chloroquine, or hydroxychloroquine was assessed using the WST-8 cell viability kit. The autophagy status in cells was analyzed by the detection of microtubule-associated light chain 3 form II (LC3-II, using immunofluorescent staining and Western blot. Acidic vesicular organelle (AVO formation in treated cells was determined by acridine orange vital staining. Inhibition of mTOR pathway by RAD001 was monitored by using a homemade quantitative polymerase chain reaction gene array, while phospho-mTOR was detected using Western blot. Induced apoptosis was determined by measurement of caspase 3/7 activity and DNA fragmentation in cells after

  17. Association between the biochemical profiles in blood and bone mineral density in Chinese Han population: findings from a cross-sectional study

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    Chen HX

    2016-11-01

    Full Text Available Hong-Xia Chen,1,2,* Li-Bing Wu,3,* Zhong-Ji Meng1 1Institute of Biomedicine, Taihe Hospital, Hubei University of Medicine, Shiyan, Hubei Province, People’s Republic of China; 2Department of Environmental, Agricultural, & Occupational Health, College of Public Health, University of Nebraska Medical Center, Omaha, NE, USA; 3Department of Nuclear Medicine, Taihe Hospital, Hubei University of Medicine, Shiyan, Hubei Province, People’s Republic of China *These authors contributed equally to this work. Abstract: This study investigated the possible correlation between blood biochemical profiles and bone mineral density (BMD in the Chinese Han population. We conducted a cross-sectional analysis using participants randomly selected from the Health Screening Center of Taihe Hospital, Hubei University of Medicine, which included a total of 285 individuals, varied in ages from 31 years to 63 years. The height, weight, and body mass index (BMI of each subject were measured, as well as fasting blood glucose (FBG, triglycerides, total cholesterol, blood uric acid (UA, blood urea nitrogen, and blood creatinine. We evaluated BMD at the wrist (grams per centimeter square using a dual-energy X-ray absorptiometry scan. The mean ages of female and male groups were 45.32±8.24 years and 46.76±9.01 years, respectively. The mean age of the study population was 46.14±8.79 years, which is similar to the general population. The mean BMI values were 22.08±2.38 kg/m2 and 24.50±2.67 kg/m2 in the female and male population, respectively, representing a statistically significant difference (P<0.05. No significant differences in levels of FBG total cholesterol, or triglycerides were seen among the male and female population. Multiple linear regression analysis was performed using BMD as outcome variables and BMI, blood UA, FBG, total cholesterol, triglycerides, urea nitrogen, and blood creatinine as covariates, and the regression equation was established as Y=0

  18. Treatment with a Ginkgo biloba extract, EGb 761, inhibits excitotoxicity in an animal model of spinocerebellar ataxia type 17

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    Huang DS

    2016-02-01

    Full Text Available Ding-Siang Huang,1,* Hsuan-Yuan Lin,1,2,* Guey-Jen Lee-Chen,1 Hsiu-Mei Hsieh-Li,1 Chung-Hsin Wu,1 Jung-Yaw Lin1,21Department of Life Science, National Taiwan Normal University, 2Institute of Biochemistry and Molecular Biology, National Taiwan University, Taipei City, Taiwan, Republic of China*These authors contributed equally to this workAbstract: Spinocerebellar ataxia type 17 (SCA 17 is a polyglutamine disease caused by the expansion of CAG/CAA repeats in the TATA box-binding protein (TBP gene. The Ginkgo biloba extract, EGb 761, contains flavonoids and terpenoids with a potential use for the treatment of neurodegenerative diseases such as Alzheimer’s and Parkinson’s diseases. The neuroprotective effects of EGb 761 are obvious, but whether the EGb 761 has therapeutic effects in SCA 17 is still unclear. To manage our issues, we have generated TBP/79Q-expressing SH-SY5Y cells and SCA 17 transgenic mice with the mutant hTBP gene. In in vitro experiment, we observed that the EGb 761 treatment decreased the amount of sodium dodecyl sulfate-insoluble proteins in the TBP/79Q-expressing SH-SY5Y cells. We further found that the EGb 761 treatment could inhibit excitotoxicity and calcium influx and reduce the expression of apoptotic markers in glutamate-treated SH-SY5Y neuroblastoma cells. In in vivo experiment, we observed that the EGb 761 treatment (100 mg/kg intraperitoneal injection per day could relieve the motor deficiencies of the SCA 17 transgenic mice. Our findings provide evidence that the EGb 761 treatment can be a remedy for SCA 17 via suppressing excitotoxicity and apoptosis in SCA 17 cell and animal models. Therefore, we suggest that EGb 761 may be a potential therapeutic agent for treating SCA 17.Keywords: spinocerebellar ataxia type 17, excitotoxicity, EGb 761, polyQ diseases, apoptosis 

  19. Peer review statement

    Science.gov (United States)

    2012-11-01

    All papers published in this volume of Journal of Physics: Conference Series have been peer reviewed through processes administered by the editors of the 26th IAHR Symposium on Hydraulic Machinery and Systems proceedings. Reviews were conducted by expert referees from the International Technical Committee to the professional and scientific standards expected of a proceedings journal published by IOP Publishing. The members of the Scientific Committee who selected and reviewed the papers included in the Proceedings of the 26th IAHR Symposium on Hydraulic Machinery and Systems are: Yulin WU Tsinghua University China François AVELLAN EPFL-LMH Switzerland (principal) Xingqi LUO Xi'an University of Sci & Tech China Martin BÖHLE Kaiserslautern University Germany Gerard BOIS Arts et Métiers ParisTech France Luca D'AGOSTINO University of Pisa Italy Eduard EGUSQUIZA Polytechnical University Catalonia Spain Richard FISHER Voith Hydro Inc USA Regiane FORTES-PATELLA Institute Polytechnique de Grenoble France Aleksandar GAJIC University of Belgrade Serbia Wei YANG China Agriculture University China YinLu YOUNG University of Michigan USA Adrian LUNGU Dunarea de Jos University of Galati Romania Arpad FAY University of Miskolcz Hungary José GONZÁLEZ Universidad de Oviedo Spain Baoshan ZHU Tsinghua University China Hongxun CHEN Shanghai University China Chisachi KATO University of Tokyo Japan Zhenyue MA Dalian University of Sci & Tech China Honggang FAN Tsinghua University China François GUIBAULT Ecole Polytechnique de Montreal Canada Pengcheng GUO Xian University of Technology China Leqing WANG Zhejiang University China Toshiaki IKOHAGI Tohoku University Japan Jiandong YANG Wuhan University China Jianzhong ZHOU Huazhong University of Sci & Tech China Jinwei LI NULL China Rennian LI Lanzhou University of Sci & Tech China Houlin LIU NULL China Juan LIU Tsinghua University China Shuhong LIU Tsinghua University China Xianwu LUO Tsinghua University China Michihiro NISHI Tsinghua

  20. SNPs, linkage disequilibrium, and chronic mountain sickness in Tibetan Chinese

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    Buroker NE

    2017-07-01

    Full Text Available Norman E Buroker,1 Xue-Han Ning,1,2,† Zhao-Nian Zhou,3 Kui Li,4 Wei-Jun Cen,4 Xiu-Feng Wu,3 Wei-Zhong Zhu,5 C Ronald Scott,1 Shi-Han Chen1 1Department of Pediatrics, University of Washington, 2Division of Cardiology, Seattle Children’s Hospital Research Foundation, Seattle, WA, USA; 3Laboratory of Hypoxia Physiology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, China; 4Lhasa People Hospital, Lhasa, Tibet; 5Center for Cardiovascular Biology and Regenerative Medicine, University of Washington, Seattle, WA, USA †Xue-Han Ning passed away on April 20, 2015 Abstract: Chronic mountain sickness (CMS is estimated at 1.2% in Tibetans living at the Qinghai–Tibetan Plateau. Eighteen single-nucleotide polymorphisms (SNPs from nine nuclear genes that have an association with CMS in Tibetans have been analyzed by using pairwise linkage disequilibrium (LD. The SNPs included are the angiotensin-converting enzyme (rs4340, the angiotensinogen (rs699, and the angiotensin II type 1 receptor (AGTR1 (rs5186 from the renin–angiotensin system. A low-density lipoprotein apolipoprotein B (rs693 SNP was also included. From the hypoxia-inducible factor oxygen signaling pathway, the endothetal Per-Arnt-Sim domain protein 1 (EPAS1 and the egl nine homolog 1 (ENGL1 (rs480902 SNPs were included in the study. SNPs from the vascular endothelial growth factor (VEGF signaling pathway included are the v-akt murine thymoma viral oncogene homolog 3 (rs4590656 and rs2291409, the endothelial cell nitric oxide synthase 3 (rs1007311 and rs1799983, and the (VEGFA (rs699947, rs34357231, rs79469752, rs13207351, rs28357093, rs1570360, rs2010963, and rs3025039. An increase in LD occurred in 40 pairwise comparisons, whereas a decrease in LD was found in 55 pairwise comparisons between the controls and CMS patients. These changes were found to occur within and between signaling pathways, which suggests that there is an interaction between SNP

  1. Depression, 5HTTLPR and BDNF Val66Met polymorphisms, and plasma BDNF levels in hemodialysis patients with chronic renal failure

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    Wang LJ

    2014-07-01

    Full Text Available Liang-Jen Wang,1,* Chih-Ken Chen,2,3,* Heng-Jung Hsu,3,4 I-Wen Wu,3,4 Chiao-Yin Sun,3,4 Chin-Chan Lee3,41Department of Child and Adolescent Psychiatry, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan; 2Department of Psychiatry, Chang Gung Memorial Hospital, Keelung, Taiwan; 3Chang Gung University School of Medicine, Taoyuan, Taiwan; 4Department of Nephrology, Chang Gung Memorial Hospital, Keelung, Taiwan *LJW and CKC are joint first authors and contributed equally to this manuscriptObjective: Depression is the most prevalent comorbid psychiatric disease among hemodialysis patients with end-stage renal disease. This cross-sectional study investigated whether depression in hemodialysis patients is associated with the polymorphism of the 5' flanking transcriptional region (5-HTTLPR of the serotonin transporter gene, the valine (Val-to-methionine (Met substitution at codon 66 (Val66Met polymorphism of the brain-derived neurotrophic factor (BDNF gene, or plasma BDNF levels.Methods: A total of 188 participants (mean age: 58.5±14.0 years; 89 men and 99 women receiving hemodialysis at the Chang Gung Memorial Hospital were recruited. The diagnosis of major depressive disorder (MDD was confirmed using the Chinese version of the Mini International Neuropsychiatric Interview. The genotypes of 5-HTTLPR and BDNF Val66Met were conducted using polymerase chain reactions plus restriction fragment length polymorphism analysis. The plasma BDNF levels were measured using an enzyme-linked immunosorbent assay kit.Results: Forty-five (23.9% patients fulfilled the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV-TR criteria for a MDD. There were no significant effects of the 5-HTTLPR or BDNF Val66Met gene polymorphism on MDD among the hemodialysis patients. The plasma BDNF levels correlated significantly with age (P=0.003 and sex (P=0.047 but not with depression, the genotypes of 5

  2. Effectiveness of high-intensity interval training on the mental and physical health of people with chronic schizophrenia

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    Wu MH

    2015-05-01

    Full Text Available Meng Hsiu Wu,1,2 Chin Pang Lee,1–3 Shih Chieh Hsu,1,3 Chia Ming Chang,1,3 Ching Yen Chen1–3 1Department of Psychiatry, Chang Gung Memorial Hospital, Linkou, Taiwan; 2Men’s Health Center, Chang Gung Memorial Hospital, Linkou, Taiwan; 3School of Medicine, Chang Gung University, Taoyuan, Taiwan Background: Low-volume high-intensity interval training (HIIT is emerging as a time-efficient exercise strategy for improving cardiorespiratory fitness and for controlling blood sugar levels and hypertension. In addition, patient acceptance of HIIT may improve adherence to exercise programs. This study evaluated the effectiveness of HIIT for improving the mental and physical health of people with chronic schizophrenia. Methods: Twenty patients attending a psychiatric day care unit volunteered for an 8-week program of HIIT. Blood pressure, resting heart rate, body weight, body mass index, waist and hip circumference, and waist-to-hip ratio were measured weekly. The Positive and Negative Syndrome Scale score was recorded at baseline and at the end of the study. Beck Depression Inventory (BDI and Beck Anxiety Inventory (BAI scores were recorded every 2 weeks. Results: Statistically significant changes occurred in the physical and mental parameters measured in the 18 patients who completed the study. Body weight, body mass index, resting heart rate, and pulse pressure decreased significantly. Mean arterial pressure and diastolic blood pressure increased significantly. Mental health scores improved, with the Negative Scale score decreasing from 31.17±5.95 to 27.78±3.57 (P<0.01 and the General Psychopathology Scale score from 14.28±2.16 to 13.00±1.72 (P<0.01. Positive Scale scores changed, but not significantly, from 12.28±2.27 to 12.33±2.00 (P=0.729. Scores on the BDI (from 19.56±15.28 to 15.89±14.33, P<0.001 and BAI (from 13.67±13.83 to 10.06±11.18, P=0.003 both improved significantly. Conclusion: This study demonstrated that HIIT has positive

  3. Self-reported psychopathology and health-related quality of life in heroin users treated with methadone

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    Chen YZ

    2012-12-01

    Full Text Available Ying-Zai Chen,1 Wei-Lieh Huang,1,2,5 Jia-Chi Shan,4,5 Yu-Hsuan Lin,1–3,5 Hung-Chieh Wu Chang,1 Li-Ren Chang1,61Department of Psychiatry, National Taiwan University Hospital, Yun-Lin Branch, 2Institute of Brain Science, National Yang-Ming University, 3Sleep Research Center, National Yang-Ming University, 4Department of Psychiatry, Cathay General Hospital, Taipei, 5Department of Psychiatry, National Taiwan University Hospital, 6Department of Psychiatry, Medical College, National Taiwan University, Taipei, TaiwanBackground: Health-related quality of life (HRQoL remains poor among heroin users, even after being treated with methadone. Evidence regarding self-reported psychopathology and HRQoL in heroin users is also limited. The present study aimed to investigate the association between self-reported psychopathology and HRQoL in Asian heroin users treated with methadone.Methods: Thirty-nine heroin users treated with methadone and 39 healthy controls were recruited. Both groups self-reported on demographic data, the Brief Symptom Rating Scale, EuroQoL-5D, and World Health Organization Questionnaire on Quality of Life: Short Form. We compared clinical characteristics, psychopathology, and HRQoL between the two study groups. Correlation and regression analyses were conducted to explore the association between psychopathology and HRQoL in the heroin user group.Results: Heroin users had more psychopathology and worse HRQoL than healthy controls. The HRQoL of heroin users had significant correlations with Brief Symptom Rating Scale scores. HRQoL could be predicted by depression, anxiety, paranoia, and additional symptoms (ie, poor appetite and sleep difficulties independently.Conclusion: Self-reported psychopathology, depression, anxiety, paranoia, poor appetite, and sleep difficulties had a negative impact on each domain of HRQoL among heroin users treated with methadone. The importance of the environmental domain of HRQoL is discussed. Clinicians

  4. Association between MDM2 SNP309 T>G polymorphism and the risk of bladder cancer: new data in a Chinese population and an updated meta-analysis

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    Xie LG

    2015-12-01

    Full Text Available Linguo Xie,1,2,* Yan Sun,2,* Tao Chen,1,2,* Dawei Tian,1,2 Yujuan Li,3 Yu Zhang,1,2 Na Ding,2 Zhonghua Shen,1,2 Hao Xu,1,2 Xuewu Nian,4 Nan Sha,1,2 Ruifa Han,1,2 Hailong Hu,1,2 Changli Wu1,2 Objective: Human murine double minute 2 protein (MDM2 is mainly a negative regulator of p53 tumor suppressor pathway. We aimed to investigate the association between MDM2 SNP309 polymorphism and bladder cancer risk. Methods: A total of 535 bladder cancer patients and 649 health controls were recruited for our study. MDM2 SNP309 T>G polymorphism was genotyped by polymerase chain reaction-ligase detection reaction method. Logistic regression was used to analyze the relationship between the genotype and susceptibility of bladder cancer. Kaplan–Meier estimates and log-rank test were obtained to analyze the association between the genotype and risk of recrudesce in nonmuscle-invasive bladder cancer patients. A multivariable Cox proportional hazards model was fitted to identify independent prognostic factors. To further investigate the association, we conducted a meta-analysis including six studies. Results: The frequency of the MDM2 SNP309 T>G polymorphism showed no significant difference between cases and controls (all P>0.05. In the stratification analysis, the results showed that G allele carriers were prone to have a significant decrease in risk of low-grade bladder cancer (adjusted odds ratio: 0.613, 95% confidence interval: 0.427–0.881, and G variant was associated with a significantly reduced risk of recurrence in nonmuscle-invasive bladder cancer patients with or without chemotherapy (P<0.05. The results of the meta-analysis showed that G allele and GG genotype of MDM2 SNP309 polymorphism were significantly associated with increased risk of bladder cancer in Caucasians (both P<0.05, and no association was observed in total populations and Asians (P>0.05. Conclusion: MDM2 SNP309 T>G polymorphism has no influence on bladder cancer risk in Asians, but

  5. Comparison of single agent versus combined chemotherapy in previously treated patients with advanced urothelial carcinoma: a meta-analysis

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    Wu XJ

    2016-03-01

    Full Text Available Xiao-Jun Wu, Yi Zhi, Peng He, Xiao-Zhou Zhou, Ji Zheng, Zhi-Wen Chen, Zhan-Song Zhou Institute of Urinary Surgery, Southwest Hospital, Third Military Medical University, Chongqing, People’s Republic of China Background: Platinum-based chemotherapy is the standard treatment for advanced urothelial cancer (UC and is generally used in the first-line setting. However, the optimal salvage treatment for previously treated UC patients is unclear. We conducted a systematic review of published clinical trials of single agent versus combined chemotherapy as salvage treatment in previously treated UC patients.Methods: Trials published between 1994 and 2015 were identified by an electronic search of public databases (MEDLINE, EMBASE, Cochrane library. All relevant studies were independently identified by two authors for inclusion. Demographic data, treatment regimens, objective response rate (ORR, disease control rate (DCR, median progression-free and overall survival (PFS, OS, and grade 3/4 toxicities were extracted and analyzed using Comprehensive Meta Analysis software (Version 2.0.Results: Fifty cohorts with 1,685 patients were included for analysis: 814 patients were treated with single agent chemotherapy and 871 with combined chemotherapy. Pooled OS was significantly higher at 1 year for combined chemotherapy than for single agent (relative risk [RR] 1.52; 95% CI: 1.01–2.37; P=0.03 but not for 2-year OS (RR 1.31; 95% CI: 0.92–1.85; P=0.064. Additionally, combined chemotherapy significantly improved ORR (RR 2.25; 95% CI: 1.60–3.18; P<0.001 and DCR (RR 1.12; 95% CI: 1.01–1.25, P=0.033 compared to single agent for advanced UC patients. As for grade 3 and 4 toxicities, more frequencies of leukopenia and thrombocytopenia were observed in the combined chemotherapy than in single agent group, while equivalent frequencies of anemia, nausea, vomiting, and diarrhea were found between the two groups.Conclusion: In comparison with single agent alone

  6. A role of Yueju in fast-onset antidepressant action on major depressive disorder and serum BDNF expression: a randomly double-blind, fluoxetine-adjunct, placebo-controlled, pilot clinical study

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    Wu R

    2015-08-01

    Full Text Available Ruyan Wu,1,* Dandan Zhu,1,* Youchun Xia,2,* Haosen Wang,2 Weiwei Tao,1 Wenda Xue,1 Baomei Xia,1 Li Ren,1 Xin Zhou,1 Guochun Li,3 Gang Chen1 1Center for Translational Systems Biology and Neuroscience, Key Laboratory of Integrative Biomedicine of Brain Diseases, Nanjing University of Chinese Medicine, Nanjing, People’s Republic of China; 2The Fourth People’s Hospital of Taizhou, Taizhou, People’s Republic of China; 3School of Basic Chinese Medicine, Nanjing University of Chinese Medicine, Nanjing, People’s Republic of China *These authors contributed equally to this work Introduction: Conventional antidepressants, including fluoxetine, have a major disadvantage in delayed onset of efficacy. Yueju, an herbal medicine used to treat mood disorders was recently found to exhibit rapid antidepressant effects. The present study was conducted to evaluate the role of Yueju in rapidly acting on major depressive disorder (MDD.Methods: Participants were MDD patients with scores of 24-item Hamilton Depression Rating Scale (HDRS-24 ≥20 and without history of antidepressant use. They randomly received daily oral doses of Yueju (23 g/day plus fluoxetine (20 mg/day (experimental group or placebo plus fluoxetine (control group for 7 days. HDRS-24 was used as the primary outcome measurement at baseline, and on days 1, 3, 5, and 7. Concentrations of serum brain-derived neurotrophic factor (BDNF were assessed at baseline and on days 1 and 7.Results: In all, 18 participants met the criteria for data analysis. Compared to baseline level, only experimental group showed significant decrease of HDRS-24 score from day 3 to day 7 (P<0.05. Experimental group also showed significant improvement compared with control group from day 3 to day 7 (P<0.05. No correlation between treatment outcomes with serum BDNF levels was observed. However, experimental group showed significant correlation for serum BDNF level on day 1 with day 7 (r=0.721, P=0.028, whereas the control

  7. Methods of suicide predict the risks and method-switching of subsequent suicide attempts: a community cohort study in Taiwan

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    Huang YC

    2014-05-01

    Full Text Available Yu-Chi Huang,1 Ya-Wen Wu,2 Chih-Ken Chen,3 Liang-Jen Wang41Department of Psychiatry, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan; 2Department of Psychiatry, Chang Gung Memorial Hospital, Keelung, Taiwan; 3Department of Psychiatry, Chang Gung Memorial Hospital, Keelung and Chang Gung University School of Medicine, Taoyuan, Taiwan; 4Department of Child and Adolescent Psychiatry, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, TaiwanObjective: Suicide is a major public health concern. This study aimed to determine the predictors of repeated suicide attempts, focusing on whether lethality level of the suicidal method predicts the risk of subsequent suicide attempts.Methods: All consecutive individuals (N=2,070 with an episode of nonfatal self-harm registered in a surveillance database provided by the Department of Health of Keelung City Government in Taiwan from January 1, 2006 to December 31, 2010 were enrolled and followed up until the end of 2011. The earliest attempt recorded in the database was defined as the index attempt. Subjects were classified according to suicide method into low-lethal and high-lethal groups. Data on time of and methods chosen for subsequent suicide attempts during the follow-up period were analyzed.Results: Of the total people screened for the study, 18.1% made a repeated suicide attempt. Subjects in the high-lethal group were more likely to be male; aged 35–64 years; and single, divorced, or widowed. Compared to other time intervals, most subsequent suicide attempts occurred within 6 months from the index attempt. The independent predictors for repeated suicide attempts were the use of low-lethal methods in the index attempt and being 35–49 years old. Using high-lethal methods and being older than 50 years were associated with changing suicide method for the second attempt.Conclusion: Lethality level of

  8. The Integration of Chuji Calendars in the Late Western Zhou Dynasty

    Science.gov (United States)

    Li, Y.

    2017-03-01

    In this paper, we investigate 23 four-element-materials contained Chuji (characters usually on bronze vessels, perhaps represent the moon phase) in the late Western Zhou Dynasty. It is assumed that all 5 elder-year data (kings' year>25 yr) should belong to the periods of king Li or king Xuan. At the same time, in order to guarantee the completeness, compatibility, and objectivity of these kinds of calendars, in the paper we build up them respectively according to the 24 characters of Chinese ancient calendar. We use the transformation platform for Chinese ancient dates to finish the calendars, consider the five different first years when both kings took their powers, set the moon age of Chuji cover any day in a lunar month, and as far as possible give every result for each material as in different kings' period. As a result, we totally derive 13 calendars according to different combinations of the characters of ancient calendars. When subdivided by the different combinations of the kings' periods, 33 solutions are obtained, but the moon phases of Chuji are usually in the second half month. The best result, with Jian Mao and the leap month in the end of the year, is related with the BC878 (BC827) as the first year of king Li (king Xuan). The coincidence rate of 23 data is 100%, and average moon phases are 19.84 days. The suboptimum choices have four solutions; the coincidence rate is 95.7%, respectively with Jian Chen and the leap month in the middle of the year; together with Jian Wu and the leap month in the middle or end of the year. We point out that these results may constitute and link respectively with other materials (even with other moon phases) as long as have the same calendar features. After adopting more materials and higher qualification, the scope of the solutions can be further limited and narrow. In addition, the different researchers can easily obtain or intercept their needed results respectively from this paper.

  9. Downregulation of human Wnt3 in gastric cancer suppresses cell proliferation and induces apoptosis

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    Wang HS

    2016-06-01

    Full Text Available Hai-Sheng Wang,1,* Xiaobo Nie,2,* Rui-Bing Wu,1 Hong-Wei Yuan,1 Yue-Hong Ma,1 Xiu-Lan Liu,1 Jian-Yu Zhang,1 Xiu-Ling Deng,1 Qin Na,1 Hai-Yan Jin,1 Yan-Chao Bian,1 Yu-Min Gao,3 Yan-Dong Wang,4 Wei-Dong Chen,1,2 1Key Laboratory of Molecular Pathology, School of Basic Medical Science, Inner Mongolia Medical University, Hohhot, 2Key Laboratory of Receptors-Mediated Gene Regulation and Drug Discovery, School of Medicine, Henan University, Kaifeng, 3Epidemiology Section, Public Health School, Inner Mongolia Medical University, Hohhot, 4State Key Laboratory of Chemical Resource Engineering, College of Life Science and Technology, Beijing University of Chemical Technology, Beijing, People’s Republic of China *These authors contributed equally to this work Abstract: Aberrant activation of Wnt/β-catenin signaling pathways is closely involved in the occurrence and progression of several types of human malignancies. However, as a fundamental component in this cascade, Wnt3 has not been well understood for the expression level and pathogenic mechanism in gastric carcinogenesis. Here, this research was undertaken to elucidate the important role of Wnt3 in gastric cancer. Wnt3 expression in gastric carcinomas and their respective normal tissues was examined by immunoblotting and immunohistochemistry. In all cases, Wnt3 expression was significantly elevated in gastric carcinomas compared with normal tissues. Knocking down Wnt3 in MGC-803 gastric cancer cells by small interfering RNAs transfection led to an obvious decrease in both transcript and protein levels. Silence of Wnt3 expression in gastric cancer cells inhibited the expression of β-catenin and cyclin D1 genes in Wnt/β-catenin pathway, significantly blocked cellular proliferation, delayed cell cycle, suppressed cell invasion and metastasis, accompanied by a higher apoptosis rate. Together, we conclude that upregulation of Wnt3 plays a crucial role in gastric tumorigenesis by inducing proliferation

  10. The effect of carvedilol and propranolol on portal hypertension in patients with cirrhosis: a meta-analysis

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    Chen S

    2015-07-01

    Full Text Available Sheng Chen,1,* Jin-Jun Wang,2,* Qin-Qin Wang,1 Jun-Wei Hu,1 Shuang Dong,1 Li-Juan Hu,1 Yi-Cheng Jian,1 Xin-Yan Liu,2 Gen-Mei Yang,2 Wu-Jun Xiong1 1Department of Hepatology, Tongji University School of Medicine, Shanghai East Hospital, 2Department of Gerontology, Shanghai Traditional Chinese Medicine University, Shanghai Putuo Central Hospital, Shanghai, People’s Republic of China *These authors contributed equally to this workPurpose: Several randomized controlled clinical trials have been conducted to investigate the role of carvedilol and propranolol on the effect of portal pressure in patients with cirrhosis, leading to controversial results. Current meta-analysis was performed to compare the efficacy of the two drugs on portal pressure.Patients and methods: Two-hundred and ninety eligible patients were recruited. Published studies were selected based on PubMed, the Cochrane Library, Chinese Journal Full-text Database, and Wanfang Database. The outcome measurements included the mean difference (MD in the percentage of hepatic vein pressure gradient reduction (%HVPG reduction, the risk ratio (RR of nonresponders in hemodynamic assessment, and the percentage of mean arterial pressure reduction (%MAP reduction. Subgroup analysis was performed.Results: Seven trials were identified (including five acute and three long-term drug administration randomized controlled trials. A summary of pooled MD between the %HVPG reduction is as follows: overall -8.62 (confidence interval [CI] -11.76, -5.48, P<0.00001, acute -10.05 (CI -14.24, -5.86, P<0.00001, and long term -6.80 (CI -11.53, -2.07, P=0.005, while summary of pooled RR of hemodynamic nonresponders with carvedilol was as follows: overall 0.64 (CI 0.51, 0.81, P=0.0002, acute 0.63 (CI 0.47, 0.85, P=0.002, and long term 0.67 (CI 0.47, 0.97, P=0.03. Both of the outcome measurements favored carvedilol. Significant heterogeneity (P<0.1, I2=92% existed between the two treatment groups in %MAP reduction

  11. Em08red, a dual functional antiproliferative emodin analogue, is a downregulator of ErbB2 expression and inducer of intracellular oxidative stress

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    Liang FP

    2015-03-01

    Full Text Available Fong-Pin Liang,1,* Jin-Cherng Lien,1,* Yu-Hua Wu,2 Chien-Shu Chen,2 Shin-Hun Juang1–3 1Graduate Institute of Pharmaceutical Chemistry, 2School of Pharmacy and Department of Pediatrics, Children’s Hospital, 3Department of Medical Research, China Medical University Hospital, Taichung, Taiwan *These authors contributed equally to this work Abstract: Expression of ErbB2 protein is inversely correlated with the prognosis in cancer patients. Consequently, strategies targeting ErbB2 remain an attractive option in treating several types of malignancies, including oral cancer. In addition, many studies have shown that emodin and emodin derivatives are able to inhibit growth of ErbB2-overexpressing tumor cells. In this study, a series of computer modeling-generated emodin analogues were synthesized and tested for their antiproliferative activity against oral cancer cell lines overexpressing ErbB2. Among these analogues, em08red (1,8-dihydroxy-9(10H-anthracenone demonstrated potent antiproliferative activity against all three tested ErbB2-overexpressing cell lines, ie, FaDu, HSC3, and OECM1. Treatment with em08red significantly downregulated activation of ErbB2 as well as the ErbB2 protein expression level in the tested cell lines and induced G2 arrest. Antiapoptosis protein (Bcl-xl and Bcl-2 expression levels were also downregulated, and active caspase-3 and caspase-9 was detected in cells after treatment with em08red. Moreover, treatment with em08red stimulated production of cytotoxic reactive oxygen species in treated cells, and this could be partially reversed by pretreatment with N-acetylcysteine. Overall, we demonstrated inhibition of ErbB2 function and induction of reactive oxygen species in tumor cells by em08red, which prevented proliferation of tumor cells and induced apoptotic cell death. Keywords: ErbB2, emodin, em08red, reactive oxygen species, structure-activity relationship 

  12. Clinical effectiveness in severe knee osteoarthritis after intra-articular platelet-rich plasma in association with hyaluronic acid injection: three case reports

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    Chen SH

    2016-09-01

    Full Text Available Szu-Hsuan Chen,1,* Ta-Shen Kuan,2,3,* Mu-Jung Kao,4 Wei-Ting Wu,1 Li-Wei Chou1,5 1Department of Physical Medicine and Rehabilitation, China Medical University Hospital, Taichung, 2Department of Physical Medicine and Rehabilitation, College of Medicine, 3Department of Physical Medicine and Rehabilitation, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, 4Department of Rehabilitation, Taipei City Hospital, Zhong Xiao Branch, Taipei, 5Graduate Institute of Acupuncture Science, College of Chinese Medicine, China Medical University, Taichung, Taiwan, Republic of China *These authors contributed equally to this work Abstract: Osteoarthritis (OA is a degenerative disorder resulting from loss of joint cartilage and underlying bone and causes pain and loss of function. The treatment of knee OA is still a challenge because of the poor self-regeneration capacity of cartilage. The nonsurgical interventions include control of the aggravating factor (such as weight control and the use of walking aids, symptomatic treatment (such as acetaminophen or nonsteroidal anti-inflammatory drugs, prolotherapy, and viscosupplementation. However, the combination of platelet-rich plasma (PRP and hyaluronic acid (HA has not been widely used because of lack of clinical evidence and several limitations in patients with severe knee OA. Three patients who suffered from knee pain and poor walking endurance were diagnosed with advanced knee OA. They underwent PRP treatment in association with intra-articular HA injection and showed pain relief and functional improvement. The follow-up standard weight-bearing X-ray images of knees also confirmed the improvement and indicated the possibility of regeneration of the articular cartilage. These cases provide clinical and radiographic evidence for a new therapy for advanced knee OA. This treatment strategy of PRP in association with HA injection can offer a chance to treat severe

  13. Factors associated with the use of percutaneous coronary intervention in elderly Chinese patients with a first ST elevated acute myocardial infarction

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    Zhou S

    2014-02-01

    Full Text Available Shan Zhou,1 Jie Chen,2 Ru-Yi Xu,1 Hai-Yun Wu2 1Chinese Navy General Hospital, Fucheng, Beijing, People's Republic of China; 2Institute of Geriatric Cardiology, Chinese PLA General Hospital, Beijing, People's Republic of China Introduction: Rapid reperfusion therapies (RT, particularly percutaneous coronary intervention (PCI, improve short- and long-term outcomes in patients with ST segment elevation myocardial infarction (STEMI. However, a substantial proportion of patients with STEMI, especially older patients, refuse or do not undergo PCI. Our study aims to identify factors associated with the use of PCI in elderly Chinese patients with their first STEMI. Method: Elderly (aged 65 years of age or over patients with STEMI were enrolled between March 2010 and August 2013 at two hospitals in Beijing. Patients with previous myocardial infarction and those with contraindications to reperfusion were excluded. A standardized questionnaire including onset time and severity of symptoms, history of angina pectoris, comorbid illnesses, functional status, family income, health insurance, education, patients' trust in treating physicians, and whether patient was acquainted with a cardiologist was used to collect data from patients or their family. Results: Five hundred and sixty-eight patients were enrolled. PCI was accepted by 432 (76% and refused by 136 (24%. Multivariate analysis showed that older age (>75 years; odds ratio [OR], 0.57; 95% confidence interval [CI], 0.23–0.78, self-rated mild symptoms (OR, 0.12; 95% CI, 0.06–0.21, lower degree of trust in treating physician (<6 in a 10 point scale; [OR, 0.14; 95% CI, 0.09–0.28], and not being acquainted with a cardiologist (OR, 0.28; 95% CI, 0.07–0.42 were associated with refusal of PCI. Conclusion: PCI was refused by almost one quarter of eligible elderly Chinese patients with a first STEMI. Age, symptom severity, and trust in physician were independent factors associated with the use of PCI in

  14. Amsacrine analog-loaded solid lipid nanoparticle to resolve insolubility for injection delivery: characterization and pharmacokinetics

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    Fang YP

    2016-03-01

    Full Text Available Yi-Ping Fang,1 Chih-Hung Chuang,2 Pao-Chu Wu,1 Yaw-Bin Huang,1 Cherng-Chyi Tzeng,3 Yeh-Long Chen,3 Ya-Ting Liu,1 Yi-Hung Tsai,1 Ming-Jun Tsai4–6 1School of Pharmacy, College of Pharmacy, 2Department of Biomedical and Environment Biology, College of Life Science, 3School of Medicinal and Applied Chemistry, College of Life Science, Kaohsiung Medical University, Kaohsiung, 4Department of Neurology, China Medical University Hospital, 5School of Medicine, Medical College, China Medical University, Taichung, 6Department of Neurology, China Medical University An-Nan Hospital, Tainan, Taiwan Abstract: Amsacrine analog is a novel chemotherapeutic agent that provides potentially broad antitumor activity when compared to traditional amsacrine. However, the major limitation of amsacrine analog is that it is highly lipophilic, making it nonconductive to intravenous administration. The aim of this study was to utilize solid lipid nanoparticles (SLN to resolve the delivery problem and to investigate the biodistribution of amsacrine analog-loaded SLN. Physicochemical characterizations of SLN, including particle size, zeta potential, entrapment efficiency, and stability, were evaluated. In vitro release behavior was also measured by the dialysis method. In vivo pharmacokinetics and biodistribution behavior of amsacrine analog were investigated and incorporated with a non invasion in vivo imaging system to confirm the localization of SLN. The results showed that amsacrine analog-loaded SLN was 36.7 nm in particle size, 0.37 in polydispersity index, and 34.5±0.047 mV in zeta potential. More than 99% of amsacrine analog was successfully entrapped in the SLN. There were no significant differences in the physicochemical properties after storage at room temperature (25°C for 1 month. Amsacrine analog-loaded SLN maintained good stability. An in vitro release study showed that amsacrine analog-loaded SLN sustained a release pattern and followed the zero equation. An

  15. TU-EF-204-02: Hiigh Quality and Sub-MSv Cerebral CT Perfusion Imaging

    Energy Technology Data Exchange (ETDEWEB)

    Li, Ke; Niu, Kai; Wu, Yijing; Chen, Guang-Hong [University of Wisconsin, Madison, WI (United States)

    2015-06-15

    Purpose: CT Perfusion (CTP) imaging is of great importance in acute ischemic stroke management due to its potential to detect hypoperfused yet salvageable tissue and distinguish it from definitely unsalvageable tissue. However, current CTP imaging suffers from poor image quality and high radiation dose (up to 5 mSv). The purpose of this work was to demonstrate that technical innovations such as Prior Image Constrained Compressed Sensing (PICCS) have the potential to address these challenges and achieve high quality and sub-mSv CTP imaging. Methods: (1) A spatial-temporal 4D cascaded system model was developed to indentify the bottlenecks in the current CTP technology; (2) A task-based framework was developed to optimize the CTP system parameters; (3) Guided by (1) and (2), PICCS was customized for the reconstruction of CTP source images. Digital anthropomorphic perfusion phantoms, animal studies, and preliminary human subject studies were used to validate and evaluate the potentials of using these innovations to advance the CTP technology. Results: The 4D cascaded model was validated in both phantom and canine stroke models. Based upon this cascaded model, it has been discovered that, as long as the spatial resolution and noise properties of the 4D source CT images are given, the 3D MTF and NPS of the final CTP maps can be analytically derived for a given set of processing methods and parameters. The cascaded model analysis also identified that the most critical technical factor in CTP is how to acquire and reconstruct high quality source images; it has very little to do with the denoising techniques often used after parametric perfusion calculations. This explained why PICCS resulted in a five-fold dose reduction or substantial improvement in image quality. Conclusion: Technical innovations generated promising results towards achieving high quality and sub-mSv CTP imaging for reliable and safe assessment of acute ischemic strokes. K. Li, K. Niu, Y. Wu: Nothing to

  16. Association between EHBP1 rs721048(A>G polymorphism and prostate cancer susceptibility: a meta-analysis of 17 studies involving 150,678 subjects

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    Ao X

    2015-07-01

    Full Text Available Xiang Ao,1,* Ying Liu,1,* Xiao-Yan Bai,1 Xinjian Qu,2 Zhaowei Xu,1 Gaolei Hu,1 Min Chen,1 Huijian Wu1,21Laboratory of Molecular Medicine & Pharmacy, School of Life Science and Biotechnology, Dalian University of Technology, Dalian, 2Laboratory of Molecular Medicine & Pharmacy, School of Life Science and Medicine, Dalian University of Technology, Panjin, Liaoning, People’s Republic of China*These authors have contributed equally to this workBackground: EHBP1 rs721048(A was first identified as a prostate cancer (PCa risk in Caucasians by genome-wide association study, but subsequent replication studies involving Caucasian and other ethnicities did not produce consistent results. The aim of this study was to obtain a more definite association between rs721048(A and PCa risk.Methods: We comprehensively searched several databases updated to September 2014, including PubMed, Web of Science, EBSCO, and Google Scholar. Two authors independently screened and reviewed the eligibility of each study. The quality of the included studies was assessed by the Newcastle–Ottawa scale. The association of rs721048(A and PCa risk was assessed by pooling odds ratios (ORs with 95% confidence intervals (CIs.Results: A total of 17 studies, including 48,135 cases and 102,543 controls, published between 2008 and 2014 were included in the meta-analysis. Overall, the pooled analysis demonstrated that rs721048(A was significantly associated with the risk of PCa under the allele model (OR=1.14, 95% CI=1.11–1.17, P=0.000. Subgroup analysis based on ethnicity revealed a ­significant association between rs721048(A and PCa in Caucasian (OR=1.14, 95% CI=1.11–1.16, P=0.000, African descent (OR=1.11, 95% CI=1.01–1.23, P=0.025, and Asian (OR=1.35, 95% CI=1.12–1.64, P=0.002.Conclusion: Our results provided strong evidence that rs721048(A could be a risk factor for PCa.Keywords: EHBP1, rs721048, meta-analysis, prostate cancer

  17. Changes in definition lead to changes in the clinical characteristics across COPD categories according to GOLD 2017: a national cross-sectional survey in China

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    Sun LN

    2017-10-01

    Full Text Available Lina Sun,* Yahong Chen,* Rui Wu, Ming Lu, Wanzhen Yao Department of Pulmonary and Critical Care Medicine, Peking University Third Hospital, Beijing, China *These authors contributed equally to this work Purpose: To investigate how the changes of definition in assessment of Global Initiative for Chronic Obstructive Lung Disease (GOLD stratification 2017 lead to changes of chronic obstructive pulmonary disease (COPD patient clinical characteristics across categories in China.Patients and methods: COPD patients from 11 medical centers in China were stratified into old and new groups A–D twice according to the GOLD 2011 and 2017 comprehensive assessment. Demography and clinical characteristics were compared between old and new groups A–D.Results: In 1,532 COPD patients, the distribution from group A to D was 330 (21.5%, 132 (8.6%, 411 (26.8%, 659 (43.0% and 557 (36.4%, 405 (26.4%, 184 (12.0%, 386 (25.2%, respectively according to GOLD 2011 and 2017. 46.7% (500/1,070 patients in high-risk groups were regrouped to low-risk groups. Compared to the old groups A and B, the new groups A and B had a higher proportion of males, lower body mass index, higher modified Medical Research Council (mMRC grade, poor pulmonary function, more patients with chronic bronchitis, and fewer patients with coronary heart disease and hypertension disease. Compared to the old groups C and D, the new groups C and D had older patients, fewer men, better pulmonary functions, frequent acute exacerbations in the previous year, and more patients with chronic bronchitis, coronary heart disease, or diabetes mellitus. The new group D had more patients with stroke than the old group D.Conclusion: In China, GOLD 2017 shifted the overall COPD comprehensive assessments distribution to more low-risk groups. The new high-risk groups had more characteristics associated with high risk of acute exacerbation and mortality. Some of the changes in demography and clinical characteristics of

  18. Smoking cessation affects the natural history of COPD

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    Bai J

    2017-11-01

    Full Text Available Jiu-Wu Bai,1 Xiao-xin Chen,2 Shengsheng Liu,3 Li Yu,1 Jin-Fu Xu11Department of Respiratory and Critical Care Medicine, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai, 2Department of Respiratory Medicine, Second Peoples Hospital of Nantong, Nantong, Jiangsu Province, 3Department of Tuberculosis, Anhui Chest Hospital, Hefei, Anhui Province, People’s Republic of China Background: Cigarette smoking is the most commonly encountered and readily identifiable risk factor for COPD. However, it is not clear which quantitative factors related to smoking influence the prognosis of COPD patients.Methods: A total of 204 patients with a long-term history of smoking were enrolled into this study and followed up for 5 years. Patients were divided into “death” or “survival” groups based on follow-up results and “quitting-smoking” or “continuing-smoking” groups based on whether they gave up smoking.Results: Patients in the death group had a longer smoking time, lower prevalence of quitting smoking, later onset of COPD symptoms, older age at quitting smoking, lower forced expiratory volume in one second (FEV1 % predicted, and lower ratio of FEV1/forced vital capacity. Age, age at quitting smoking, and FEV1% predicted were independently associated with mortality from COPD. Compared to the continuing-smoking group, the quitting-smoking group had a lower mortality rate, longer course of COPD, earlier onset of COPD symptoms, and lower residual volume percent predicted. During the 5-year follow-up, 113 deaths were recorded (quitting-smoking group: n=92; 40 deaths; continuing-smoking group: n=112; 73 deaths. The mortality risk remained significantly higher in the continuing-smoking group than the quitting-smoking group (log-rank test, 13.59; P=0.0002.Conclusion: Smoking time may be related to the mortality rate from COPD. Smoking cessation has the greatest capacity to influence the natural history of COPD.Keywords: chronic

  19. Neoadjuvant chemotherapy combined with limb salvage surgery in patients with limb osteosarcoma of Enneking stage II: a retrospective study

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    Yuan G

    2017-05-01

    Full Text Available Guangke Yuan,1,2 Jingming Chen,2 Dongjin Wu,1 Chunzheng Gao1 1Department of Orthopedics, The Second Hospital of Shandong University, Jinan, 2Department of Orthopedics, Yidu Central Hospital of Weifang, Weifang, Shandong, People’s Republic of China Objective: To explore the effect of neoadjuvant chemotherapy combined with limb salvage surgery in patients with limb osteosarcoma of Enneking stage II. Patients and methods: Medical records of 98 patients who met the inclusion criteria were retrospectively analyzed. Of these patients, 56 cases who received neoadjuvant chemotherapy combined with limb salvage surgery were listed as group A, while another 42 patients who received limb salvage surgery combined with adjuvant chemotherapy were listed as group B. The recurrence and metastasis rate, survival rate, limb function and incidence of adverse reactions were compared between the two groups. Results: All 98 patients completed the treatment in this study. Baseline characteristics showed no significant differences between group A and group B, including age, gender, tumor location, maximum tumor diameter and Enneking stage (all P>0.05. The total metastasis and recurrence rate of group A was significantly lower than that of group B (25.0% vs 47.6%, χ2=5.419, P=0.020. The Kaplan–Meier method showed that progression-free survival (PFS (log-rank χ2=4.014, P=0.045 and overall survival (OS (log-rank χ2=3.859, P=0.049 of group A were both significantly higher than those of group B. There was no significant difference in the incidence of grades III–IV adverse reactions between the two groups (all P>0.05. The excellent and good rate of limb function in group A was significantly higher than that in group B (83.9% vs 66.7%, χ2=3.982, P=0.046. Conclusion: Neoadjuvant chemotherapy combined with limb salvage surgery for patients with Enneking stage IIA or IIB limb osteosarcoma patients has better efficacy and can significantly improve limb function of

  20. Nimotuzumab combined with radiotherapy for esophageal cancer: preliminary study of a Phase II clinical trial

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    Liang J

    2013-11-01

    Full Text Available Jun Liang,1 Mingyan E,2 Gang Wu,3 Lujun Zhao,4 Xia Li,5 Xia Xiu,6 Ning Li,1 Bo Chen,1 Zhouguang Hui,1 Jima Lv,1 Hui Fang,1 Yu Tang,1 Nan Bi,1 Wenqing Wang,1 Yirui Zhai,1 Tao Li,1 Dongfu Chen,1 Shuangmei Zou,7 Ning Lu,7 Rolando Perez-Rodríguez,8 Junqi Zheng,9 Luhua Wang11Department of Radiotherapy, Cancer Hospital, Chinese Academy of Medical Sciences, Beijing, People's Republic of China; 2Department of Radiotherapy, Cancer Hospital of Harbin Medical University, Harbin, People's Republic of China; 3Department of Radiotherapy, Tongji Cancer Center Hospital, Wuhan, People's Republic of China; 4Department of Radiotherapy, Cancer Hospital of Tianjin Medical University, Tianjin, People's Republic of China; 5Department of Radiotherapy, LiaoNing Province Cancer Hospital, Shenyang, People's Republic of China; 6Department of Radiotherapy, Beijing Hospital, Beijing, People's Republic of China; 7Department of Pathology, Cancer Hospital, Chinese Academy of Medical Sciences, Beijing, People's Republic of China; 8Center of Molecular Immunology, Havana, Cuba; 9School of Medicine, Tongji University, Shanghai, People's Republic of ChinaObjective: To determine the safety and therapeutic effects of nimotuzumab (h-R3 combined with radiotherapy in esophageal cancer.Methods: This Phase II clinical trial involved 42 patients with stage II (inoperable or refused surgery to stage IV (supraclavicular lymph node metastasis only esophageal cancers treated between November 2008 and July 2010. All patients had squamous cell carcinomas, and all received three-dimensional conformal radiotherapy and 200 mg nimotuzumab per week during radiotherapy.Results: There were 9, 25, and 8 patients with stage II, III and IV disease, respectively. All except two patients received 50–70 Gy radiation; 37 patients (88.1% received more than five nimotuzumab doses. Grade III toxicities (21.4% of all adverse events included esophagitis and gastrointestinal, dermatological and hematological

  1. Cyanobacterial crust induction using two non-previously tested cyanobacterial inoculants: crusting capability and role of EPSs

    Science.gov (United States)

    Mugnai, Gianmarco; Rossi, Federico; De Philippis, Roberto

    2017-04-01

    stable (tightly bound EPSs, TB-EPSs), which were deemed having different functions (Chen et al., 2014). The results demonstrated how differently (and complementarily in some ways) these two strains behave when applied on a poor sandy substrate, producing cyanobacterial crusts having different morphology. The outcomes of this study suggest the potential of Schizothrix AMPL1601 and Leptolyngbia ohadii as valid biotechnological tools for improving the properties of poor arid soils, allowing to design proper rehabilitation or restoration models. In addition, this study provided new insight on the characteristics of the cyanobacterial EPSs, secreted under a constrained condition, compared to a non-nutrient limited and optimal one. Chen, L., Rossi, F., Deng, S., Liu, Y., Wang, G., Adessi, A., De Philippis, R., 2014. Macromolecular and chemical features of the excreted extracellular polysaccharides in induced biological soil crusts of different ages. Soil Biology and Biochemistry 78, 1-9. doi:10.1016/j.soilbio.2014.07.004 Lan, S., Zhang, Q., Wu, L., Liu, Y., Zhang, D., Hu, C., 2014. Artificially Accelerating the Reversal of Desertification: Cyanobacterial Inoculation Facilitates the Succession of Vegetation Communities. Environmental Science & Technology 48, 307-315. doi:10.1021/es403785j

  2. Supplementation of omega 3 fatty acids may improve hyperactivity, lethargy, and stereotypy in children with autism spectrum disorders: a meta-analysis of randomized controlled trials

    Directory of Open Access Journals (Sweden)

    Cheng YS

    2017-10-01

    Full Text Available Yu-Shian Cheng,1 Ping-Tao Tseng,1,2 Yen-Wen Chen,3 Brendon Stubbs,4–6 Wei-Chieh Yang,7 Tien-Yu Chen,8,9 Ching-Kuan Wu,1 Pao-Yen Lin10,11 1Department of Psychiatry, Tsyr-Huey Mental Hospital, Kaohsiung Jen-Ai’s Home, 2WinShine Clinics in Specialty of Psychiatry, 3Prospect Clinic for Otorhinolaryngology & Neurology, Kaohsiung, Taiwan, Republic of China; 4Physiotherapy Department, South London and Maudsley NHS Foundation Trust, 5Health Service and Population Research Department, Institute of Psychiatry, Psychology and Neuroscience, King’s College London, London, 6Faculty of Health, Social Care and Education, Anglia Ruskin University, Chelmsford, UK; 7Department of Pediatrics, DA-AN Women and Children Hospital, Tainan, 8Department of Psychiatry, Tri-Service General Hospital, Taipei, 9School of Medicine, National Defense Medical Center, Taipei, 10Department of Psychiatry, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, 11Institute for Translational Research in Biomedical Sciences, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan, Republic of China Aim: Deficiency of omega 3 fatty acids may be linked to autism spectrum disorder (ASD. Evidence about the potential therapeutic effects of supplementation of omega 3 fatty acids is lacking in ASD patients.Methods: We searched major electronic databases from inception to June 21, 2017, for randomized clinical trials, which compared treatment outcomes between supplementation of omega 3 fatty acids and placebo in patients with ASD. An exploratory random-effects meta-analysis of the included studies was undertaken.Results and conclusion: Six trials were included (n=194. Meta-analysis showed that supplementation of omega 3 fatty acids improved hyperactivity (difference in means =-2.692, 95% confidence interval [CI] =-5.364 to -0.020, P=0.048, studies =4, n=109, lethargy (difference in means =-1.969, 95% CI =-3.566 to -0.372, P=0.016, studies =4, n=109, and

  3. Cost-effectiveness of amlodipine compared with valsartan in preventing stroke and myocardial infarction among hypertensive patients in Taiwan

    Directory of Open Access Journals (Sweden)

    Chan L

    2016-05-01

    Full Text Available Lung Chan,1 Chen-Huan Chen,2 Juey-Jen Hwang,3 San-Jou Yeh,4 Kou-Gi Shyu,5 Ruey-Tay Lin,6 Yi-Heng Li,7 Larry Z Liu,8 Jim Z Li,9 Wen-Yi Shau,10 Te-Chang Weng,10 1Department of Neurology, Shuang-Ho Hospital, School of Medicine, College of Medicine, Taipei Medical University, New Taipei, 2Department of Internal Medicine, Faculty of Medicine, National Yang-Ming University, 3Division of Cardiology, Department of Internal Medicine, National Taiwan University Hospital, Taipei, 4Division of Cardiology, Department of Internal Medicine, Chang Gung Memorial Hospital, Taoyuan, 5Division of Cardiology, Department of Internal Medicine, Shin Kong Wu Ho-Su Memorial Hospital, Taipei, 6Department of Neurology, Kaohsiung Medical University Hospital, Kaohsiung, 7Division of Cardiology, Department of Internal Medicine, National Cheng Kung University Hospital, Tainan, Taiwan; 8Pfizer Inc, New York, NY, USA; 9Pfizer Inc, San Diego, CA ,USA; 10Pfizer Ltd., New Taipei City, Taiwan Abstract: Hypertension is a major risk factor for strokes and myocardial infarction (MI. Given its effectiveness and safety profile, the calcium channel blocker amlodipine is among the most frequently prescribed antihypertensive drugs. This analysis was conducted to determine the costs and quality-adjusted life years (QALYs associated with the use of amlodipine and valsartan, an angiotensin II receptor blocker, in preventing stroke and MI in Taiwanese hypertensive patients. A state transition (Markov model was developed to compare the 5-year costs and QALYs for amlodipine and valsartan. Effectiveness data were based on the NAGOYA HEART Study, local studies, and a published meta-analysis. Utility data and costs of MI and stroke were retrieved from the published literature. Medical costs were based on the literature and inflated to 2011 prices; drug costs were based on National Health Insurance prices in 2014. A 3% discount rate was used for costs and QALYs and a third-party payer perspective

  4. Review of the East Palaearctic and North Oriental Psyttalia Walker, with the description of three new species (Hymenoptera, Braconidae, Opiinae)

    NARCIS (Netherlands)

    Wu, Q.; Achterberg, van C.; Tan, J.-L.; Chen, X.-X.

    2016-01-01

    The East Palaearctic and North Oriental species of the genus Psyttalia Walker (Hymenoptera, Braconidae, Opiinae) are reviewed. Three new species are described and illustrated: P. latinervis Wu & van Achterberg, sp. n. and P. majocellata Wu & van Achterberg, sp. n. from China, and P. spectabilis van

  5. Developing institutional collaboration between Wageningen university and the Chinese academy of agricultural sciences

    NARCIS (Netherlands)

    Bonnema, A.B.; Lin, Z.; Qu, L.; Jacobsen, E.

    2006-01-01

    Scientific co-operation between the Chinese Academy of Agricultural Sciences (CAAS) and Wageningen University (WU) has been underway since 1990, especially in the field of plant sciences. In 2001, CAAS and WU initiated a formal joint PhD training programme to further structure their co-operation.

  6. Journal of Earth System Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Earth System Science. ShaoFei Wu. Articles written in Journal of Earth System Science. Volume 126 Issue 4 June 2017 pp 48. Joint pattern of seasonal hydrological droughts and floods alternation in China's Huai River Basin using the multivariate L-moments · ShaoFei Wu Xiang Zhang DunXian ...

  7. DMPD: Mechanism of age-associated up-regulation in macrophage PGE2 synthesis. [Dynamic Macrophage Pathway CSML Database

    Lifescience Database Archive (English)

    Full Text Available 15331118 Mechanism of age-associated up-regulation in macrophage PGE2 synthesis. Wu...e-associated up-regulation in macrophage PGE2 synthesis. PubmedID 15331118 Title Mechanism of age-associated... up-regulation in macrophage PGE2 synthesis. Authors Wu D, Meydani SN. Publicatio

  8. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science. Anhua Wu. Articles written in Bulletin of Materials Science. Volume 27 Issue 4 August 2004 pp 333-336 Crystal Growth. Bridgman growth and defects of Nd : Sr3Ga2Ge4O14 laser crystals · Jiaxuan Ding Anhua Wu Jiayue Xu · More Details Abstract Fulltext PDF.

  9. Women in physics

    CERN Document Server

    Indovino, Shaina

    2013-01-01

    What does it take to be a physicist? Lise Meitner, Katharine Blodgett, Maria Goeppert-Mayer, Chien-Shiung Wu, Ursula Franklin, Argelia Velez-Rodriguez, Sau Lan Wu, Shirley Ann Jackson, Lisa Randall and opportunities for women in physics today.

  10. Software Quality Measurement for Distributed Systems. Volume 1.

    Science.gov (United States)

    1983-07-01

    Institute of Technology, Pasadena, CA, Jun. 1980 (CHW) ( Chu , W. and Chew, P., "Computer Networks: A Tutorial", IEEE Comput. Soc., New York, 1980) (COD...Pragmatic View of Distributed Processing Systems", IEEE Conput. Soc., Los Alemedas, California, 1980) (WU) Wu, Chuan-lin, & Feng, Tsu -yun. "A software

  11. Nested Nanotherapeutics for Drug Synergy Enhancement in Breast Cancer Therapy

    Science.gov (United States)

    2014-09-01

    feedback loop activation – Task 2, Aim 2 Reportable Outcomes • Refereed publications - Ruiz-Esparza, G.U.; Wu, S.; Segura-Ibarra, V.; Cara , F.E...32, 2309-23. *Contributed equally - Blanco, E.; Sangai, T.; Wu, S.; Hsiao, A.; Ruiz-Esparza, G.U.; Gonzalez- Delgado, C.A.; Cara , F.E.; Granados

  12. Sadhana | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Sadhana. M-J Wu. Articles written in Sadhana. Volume 35 Issue 5 October 2010 pp 631-647. Development of numerical modelling of analysis program for energy-dissipating behaviour of velocity dependent hydraulic damper · M-H Shih W-P Sung M-J Wu · More Details Abstract Fulltext PDF. A relief valve ...

  13. Fundamental Investigations into the Infrared Properties of Carbon Nanotubes

    Science.gov (United States)

    2013-01-23

    Vallejo , Rongtao Lu, Judy Wu. Development of Textured Magnesium Oxide Templates on Amorphous Polymer SurfacesUsing Ion-Beam-Assisted Deposition, Applied...Applied Physics Letters 99, 023111 (2011) 18. A. Elliot, Vallejo , R.T. Lu, and J.Z. Wu, “Development of Textured Magnesium Oxides Templates on

  14. 团队悟性创新理论框架

    DEFF Research Database (Denmark)

    Xin, Wang; Li, Peter Ping

    2017-01-01

    ,imagination, symbolism, metaphor, analogy, and insight. Based on the literature about knowledge creation and organizational learning, the new framework of "Wu"-based team-level innovation emerges from four cases of "Wu"-based knowledge creation in a Chinese aerospace team, with a special reference to the Western notion...

  15. Bulletin of the Chemical Society of Ethiopia - Vol 30, No 1 (2016)

    African Journals Online (AJOL)

    Synthesis, Hirshfeld surface analyses and magnetism of a 1D Mn(II) complex · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. L. Lu, J. Wang, W. P. Wu, X. R. Wu, A. Kumar, 111-118. http://dx.doi.org/10.4314/bcse.v30i1.10 ...

  16. Hopes for Confucian Pedagogy in China?

    Science.gov (United States)

    Hayhoe, Ruth

    2014-01-01

    This commentary on Wu Zongjie's article "Interpretation, autonomy and transformation: Chinese pedagogic discourse in a cross-cultural perspective" begins by suggesting the usefulness of Wu's polar opposite depiction of Confucian and modern pedagogy as ideal types for comparative exploration. It goes on to suggest that the term…

  17. Reference: 188 [Arabidopsis Phenome Database[Archive

    Lifescience Database Archive (English)

    Full Text Available 188 http://metadb.riken.jp/db/SciNetS_ria224i/cria224u4ria224u15753038i Wu Xuelin ...STIMPY/WOX9 for Arabidopsis meristem growth and maintenance. 5 436-40 15753038 2005 Mar Current biology Dabi Tsegaye|Weigel Detlef|Wu Xuelin

  18. 77 FR 34342 - Order Denying Export Privileges

    Science.gov (United States)

    2012-06-11

    ... Alex Wu, Currently Incarcerated at: Inmate Number: 40887-424 FMC Devens, Federal Medical Center, P.O... addresses at: Inmate Number: 40887-424, FMC Devens, Federal Medical Center, P.O. Box 879, Ayer, MA 01432 and... person, firm, corporation, or business organization related to Wu by affiliation, ownership, control or...

  19. Expression analysis and characteristics of hypothetical protein ...

    African Journals Online (AJOL)

    W Zhang, H Lan, T Wu, C Jiang, Z Lv, Z Nie, X Wu, Y Zhang. Abstract. We cloned a cDNA from silkworm pupal cDNA library and found that, it encodes LOC778500 protein (a “hypothetical protein” in the National Center for Biotechnology Information (NCBI) database). Thus, we named it BmLOC778500 (Bombyx mori ...

  20. Wave propagation, scattering and emission in complex media

    Science.gov (United States)

    Jin, Ya-Qiu

    I. Polarimetric scattering and SAR imagery. EM wave propagation and scattering in polarimetric SAR interferometry / S. R. Cloude. Terrain topographic inversion from single-pass polarimetric SAR image data by using polarimetric stokes parameters and morphological algorithm / Y. Q. Jin, L. Luo. Road detection in forested area using polarimetric SAR / G. W. Dong ... [et al.]. Research on some problems about SAR radiometric resolution / G. Dong ... [et al.]. A fast image matching algorithm for remote sensing applications / Z. Q. Hou ... [et al.]. A new algorithm of noised remote sensing image fusion based on steerable filters / X. Kang ... [et al.]. Adaptive noise reduction of InSAR data based on anisotropic diffusion models and their applications to phase unwrapping / C. Wang, X. Gao, H. Zhang -- II. Scattering from randomly rough surfaces. Modeling tools for backscattering from rough surfaces / A. K. Fung, K. S. Chen. Pseudo-nondiffracting beams from rough surface scattering / E. R. Méndez, T. A. Leskova, A. A. Maradudin. Surface roughness clutter effects in GPR modeling and detection / C. Rappaport. Scattering from rough surfaces with small slopes / M. Saillard, G. Soriano. Polarization and spectral characteristics of radar signals reflected by sea-surface / V. A. Butko, V. A. Khlusov, L. I. Sharygina. Simulation of microwave scattering from wind-driven ocean surfaces / M. Y. Xia ... [et al.]. HF surface wave radar tests at the Eastern China Sea / X. B. Wu ... [et al.] -- III. Electromagnetics of complex materials. Wave propagation in plane-parallel metamaterial and constitutive relations / A. Ishimaru ... [et al.]. Two dimensional periodic approach for the study of left-handed metamaterials / T. M. Grzegorczyk ... [et al.]. Numerical analysis of the effective constitutive parameters of a random medium containing small chiral spheres / Y. Nanbu, T. Matsuoka, M. Tateiba. Wave propagation in inhomogeneous media: from the Helmholtz to the Ginzburg -Landau equation / M

  1. First known terrestrial impact of a binary asteroid from a main belt breakup event.

    Science.gov (United States)

    Ormö, Jens; Sturkell, Erik; Alwmark, Carl; Melosh, Jay

    2014-10-23

    Approximately 470 million years ago one of the largest cosmic catastrophes occurred in our solar system since the accretion of the planets. A 200-km large asteroid was disrupted by a collision in the Main Asteroid Belt, which spawned fragments into Earth crossing orbits. This had tremendous consequences for the meteorite production and cratering rate during several millions of years following the event. The 7.5-km wide Lockne crater, central Sweden, is known to be a member of this family. We here provide evidence that Lockne and its nearby companion, the 0.7-km diameter, contemporaneous, Målingen crater, formed by the impact of a binary, presumably 'rubble pile' asteroid. This newly discovered crater doublet provides a unique reference for impacts by combined, and poorly consolidated projectiles, as well as for the development of binary asteroids.

  2. Kønsudvikling hos sønner af gartneriansatte kvinder

    DEFF Research Database (Denmark)

    Andersen, Helle Raun; Schmidt, Ida Maria; Grandjean, Philippe

    2008-01-01

      Flere pesticider er vist at være hor­mon­for­styr­rende i celle- eller dyreforsøg og epi­de­mio­lo­gi­ske undersøgelser tyder på, at tidlig eks­po­ne­ring for pesticider kan påvirke ud­vik­lingen af for­plantnings- og hor­mon­syste­met hos men­ne­sker. Formålet med denne prospektive under­søg­e...... un­der­søgelsen er tid­ligere publiceret i Environ­mental Health Perspective 2008;116:566-72. Udgivelsesdato: December...

  3. How the rock fabrics can control the physical properties - A contribution to the understanding of carbonate reservoirs

    Energy Technology Data Exchange (ETDEWEB)

    Duerrast, H.; Siegesmund, S. [Goettingen Univ. (Germany)

    1998-12-31

    The correlation between microfabrics and physical properties will be illustrated in detail on three dolomitic carbonate reservoir rocks with different porosity. For this study core segments from the Zechstein Ca2-layer (Permian) of the Northwest German Basin were kindly provided by the Preussag Energie GmbH, Lingen. The mineral composition was determined by using the X-ray diffraction method. Petrographic and detailed investigation of the microfabrics, including the distribution and orientation of the cracks were done macroscopally (core segments) and microscopally with the optical microscope and the Scanning Electron Microscope (thin sections in three orthogonally to each other oriented directions). Different kinds of petrophysical measurements were carried out, e.g. porosity, permeability, electrical conductivity, seismic velocities. (orig.)

  4. In-field Calibration of a Fast Neutron Collar for the Measurement of Fresh PWR Fuel Assemblies

    Energy Technology Data Exchange (ETDEWEB)

    Swinhoe, Martyn Thomas [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); De Baere, Paul [European Commission (Luxembourg). Euratom Safeguards

    2015-04-17

    A new neutron collar has been designed for the measurement of fresh LEU fuel assemblies. This collar uses “fast mode” measurement to reduce the effect of burnable poison rods on the assay and thus reduce the dependence on the operator’s declaration. The new collar design reduces effect of poison rods considerably. Instead of 12 pins of 5.2% Gd causing a 20.4% effect, as in the standard thermal mode collar, they only cause a 3.2% effect in the new collar. However it has higher efficiency so that reasonably precise measurements can be made in 25 minutes, rather than the 1 hour of previous collars. The new collar is fully compatible with the use of the standard data collection and analysis code INCC. This report describes the calibration that was made with a mock-up assembly at Los Alamos National Laboratory and with actual assemblies at the AREVA Fuel fabrication Plant in Lingen, Germany.

  5. synthetic approaches

    African Journals Online (AJOL)

    Dr Mdachi

    Avances en Quimica 8: 145-151. Chen J, Zhou L, Tan CK and Yeung Y-Y. 2012 An Enantioselective Approach toward 3,4-Dihydroisocoumarin through the Bromocyclization of Styrene-type. Carboxylic Acids. J. Org. Chem.77: 999-. 1009. Chen P-Y, Wang Y-F, Chen L-Y, Wang G-. L and Wang E-C 2013 Reaction of o-.

  6. Mechanical Properties of EPON 826/DEA Epoxy

    Science.gov (United States)

    2008-07-26

    properties of Epon 826 and Epon 828 , a similar resin, have been studied by several authors (Katz et al. 1980; Enns and Gillham 1983; Truong 1990; Kozey and...on hydrostatic pressure up to 17 MPa. Chen and Zhang (1997) and Chen and Zhou (1998) studied Epon 828 with curing agent T-403 under compressive...2002) Chen, W., Zhang, X.: Dynamic response of Epon 828 /T-403 under multiaxial loading at various temperatures. J. Eng. Mater. Technol. Trans. ASME

  7. Stochastic Non-Linear Flutter of Aeroelastic Structures.

    Science.gov (United States)

    1985-10-21

    diffusion coefficient. The impulse response of a single degree-of-freedom system with random parameters was determined by Chen and Soroka [25] by using a...the dispersion from the * mean becomes substantial. In another study, Chen and Soroka [26] con- sidered the response of multi-degree-of-freedom... Soroka , W. W., "Impulse Response of a Dynamic System with Statistical Properties," J. Sound and Vibration 31, pp. 309-314, 1973. 26. Chen, P. C. and

  8. The Measurement of Strain Fields by X-Ray Topographic Contour Mapping.

    Science.gov (United States)

    1985-05-01

    FIELDS BY X-RAY TOPOGRAPHIC CONTOUR MAPPING S.R. Stock, Haydn Chen and H.K. Birnbaum University of Illinois Department of Metallurgy Urbana, IL 61801...TOPOGRAPHIC CONTOUR MAPPING S. R. Stock*# Haydn Chen and H. K. Birnbaum Department of Metallurgy and Mining Engineering University of Illinois at Urbana...Birnbaum, - - H. K. and Chen, Haydn , Topographic EXAFS, Nature 309: 336 . - (1984). Hart, M., Bragg angle measurement and mapping, J. Cryst. Growth

  9. Studies of Deformation in Niobium by X-Ray Topographic Methods.

    Science.gov (United States)

    1985-01-01

    STANDARDS-|1%3-A ! iL STUDIES OF DEFORMATION IN NIOBIUM BY X-RAY TOPOGRAPHIC METHODS CV S.R. Stock, Haydn Chen and H,K, Birnbaum University of...Rt. Stock*, Haydn Chen and H. K. Birnbaum J icatio. -: Department of Metallurgy and Mining Engineering By - and Materials Research Laboratory... Haydn Chen and H. K. Birnbaum, "Equi-Inclination Contour Mapping of Strain Fields," in press in Applications of X-Ray . Topographic Methods to Materials

  10. 77 FR 28880 - Ocean Transportation Intermediary License Applicants

    Science.gov (United States)

    2012-05-16

    ..., Inglewood, CA 90301, Officers: Edison Chen, Manager (Qualifying Individual), Wei-Nung (Janus) Lin, Member... A. Case, Vice President (Qualifying Individual), Thomas C. Case, President, Application Type: Trade...

  11. Taiwan in 2004: Elections, Referenda, and Other Democratic Challenges

    National Research Council Canada - National Science Library

    Dumbaugh, Kerry

    2005-01-01

    .... In both the presidential and legislative election campaigns, Chen emphasized gaining a separate international identity for Taiwan -- an emphasis to which Beijing strenuously objected as dangerously...

  12. Committees

    Science.gov (United States)

    2012-11-01

    -RESIGA Politehnica University of Timisoara Romania Kazuhiro TANAKA Kyushu Institute of Technology Japan Yoshinobu TSUJIMOTO Osaka University Japan Local Organizing Committee Chairman Yulin WU Tsinghua University Beijing Executive Chairman Zhengwei WANG Tsinghua University Beijing Members Shuliang CAO Tsinghua University Beijing Cichang CHEN South West University of Petroleum Chengdu Hongxun CHEN Shanghai University Shanghai Jiang DAI China Sanxia General Co Yichang Huashu DOU National University of Singapore Singapore Fengqin HAN Huanan University of Sci & Tech Guangzhou Kun LI Hefei Inst of General Machinery Hefei Rennian LI Lanzhou University of Sci & Tech Lanzhou Wanhong LI National Natural Science Foundation of China Beijing Chao LIU Yangzhou University Yangzhou Li LU China Inst of Water Resources and Hydropower Research Beijing Xingqi LUO Xi'an University of Tech Xi'an Zhenyue MA Dalian University of Sci & Tech Dalian Jiegang MU Zhejiang University of Tech Hangzhou Daqing QIN Harbin Electric Machinery Group Harbin Fujun WANG China Agriculture University Beijing Guoyu WANG Beijing Institute of Technology (BIT) Beijing Leqin WANG Zhejiang University Hangzhou Yuzhen WU NERCSPV Beijing Hongyuan XU Tsinghua University Beijing Jiandong YANG Wuhan University Wuhan Minguan YANG Jiangsu University Zhenjiang Shouqi YUAN Jiangsu University Zhenjiang Lefu ZHANG Harbin Electric Machinery Group Harbin Lixiang ZHANG Yunnan University of Sci & Tech Kunming Shengchang ZHANG Zhejiang University of Tech Hangzhou Kun ZHAO China Water & Electric Consulting Corp Beijing Yuan ZHENG Hehai University Nanjing Jianzhong ZHOU Huazhong University of Sci & Tech Wuhan Lingjiu ZHOU China Agriculture University Beijing Hongwu ZHU China Petroleum University Beijing Zuchao ZHU Zhejiang Sci-Tech University Hangzhou Secretaries Shuhong LIU (Academic), liushuhong@tsinghua.edu.cn Xianwu LUO (Registration), luoxw@tsinghua.edu.cn Baoshan ZHU (Finance), bszhu@mail.tsinghua.edu.cn

  13. An investigation into the effects of different warm-up modalities on specific motor skills related to soccer performance.

    Science.gov (United States)

    Fletcher, Iain M; Monte-Colombo, Mathew M

    2010-08-01

    The aim of this study was to investigate the effect of different warm-up stretch modalities on specific high-speed motor capabilities important to soccer performance. Twenty-seven male soccer players performed 3 warm-up conditions, active warm-up (WU), WU with static stretching (SPS), and WU with dynamic stretching (ADS). Heart rate, countermovement jump, 20-m sprint, and Balsom agility tests were performed after each intervention. Vertical jump heights were significantly greater (p < 0.01) in the WU and ADS conditions compared to those in the SPS trial. The 20-m sprint and agility times showed that the SPS condition was significantly slower (p < 0.01) than the WU and ADS conditions, with the ADS trial being significantly faster (p < 0.05) than the WU condition. Heart rate was significantly higher (p < 0.01) for participants post-WU and -ADS trials compared to the SPS condition. These findings suggest that the superior performance of the dynamic stretch and warm-up-only conditions compared to the static stretch condition may be linked to increases in heart rate. The reasons for the dynamic stretch trial superiority compared to the warm-up condition are less clear and as yet to be established. We recommend for optimal performance, specific dynamic stretches be employed as part of a warm-up, rather than the traditional static stretches.

  14. Impact of in-band interference on a wake-up radio system in wireless sensor networks

    Science.gov (United States)

    Lebreton, J. M.; Murad, N. M.; Lorion, R.

    2017-05-01

    The energy efficiency of Wireless Sensor Networks (WSNs) is considerably improved with Wake-up Radio (WuR) systems. However, their resilience to interference is often neglected in the literature. This might be an issue due to the proliferation of wireless devices and the growing field of internet of things. In this paper, we evaluate the impact of in-band interference from wireless devices on a WuR system. The approach proves that WuR systems are still performing well when coexisting with external wireless networks, even if the energy-efficiency is slightly reduced.

  15. An Analysis of Mine Water Inrush Based on Fractal and Non-Darcy Seepage Theory

    Science.gov (United States)

    Wu, Jinsui; Cai, Jianchao; Zhao, Dongyun; Chen, Xuexi

    2014-09-01

    Mining rock mechanics is a new cross subject of mechanics and mining engineering, the seepage theory is one of the important research directions. This paper combines Wu-fractal/Ergun high-speed flow theory and dynamic system instability, reveals the influence factors of mine water inrush. Research shows that: Mine water inrush related to rock porosity, particle size, shape, fractal dimension, ratio of pore and throat, and other factors. Compared the critical Reynolds number which are got from Wu-fractal model and Ergun equation, Wu-fractal model can reveal more influence factors of mine water inrush than Ergun equation.

  16. The Effect of a Winglet on the Spatial Vortex of a Slender Body at High Angle of Attack,

    Science.gov (United States)

    1986-07-07

    OF A SLENDER BODY AT HIGH 0)ANGLE OF ATTACK !,D) toF by ~Wang Zixing, Wu Genxing Approved for public release;L"’J Distribution unlimited. q Ui...ATTACK By: Wang Zixing, Wu Genxing English pages: 12 Source: Konggi Donglixue Xuebao, Vol. 3, Nr. 1, 1985, pp. 49-53 Country of origin: China Translated by...U ~ ~ ’~ IL--c-k. au -ILI . W THE EFFECT OF A WINGLET ON THE SPATIAL VORTEX OF A SLENDER BODY AT HIGH ANGLE OF ATTACK Wang Zixing Wu Genxing

  17. People’s Republic of China Scientific Abstracts No. 179

    Science.gov (United States)

    1977-11-08

    No 2, April 1977 7 CHIH-WU HSUEH-PAO [ACTA BOTANICA SINICA] No 2, June 1977 22 I-CH’UAN HSUEH-PAO [ACTA GENETICA SINICA] No 1...sources with fluorescent dyes and applications in forensic medicine. 10 ATITHOR: WU Min [O702 4t ] ORG: Institute of Oncology...photorespirators. 8650 C50J 4009 29 ACTA GENETICA SINICA AUTHOR: WU An-chiu [0702 1344 0036] ORG: Technique Staff of San-t’ai Commune Fu County

  18. influence of storage temperatures on physicochemical sensory and ...

    African Journals Online (AJOL)

    E-Shop

    2012-02-14

    Feb 14, 2012 ... (2009). Beta-carotene, lycopene, and alpha-tocopherol contents of selected Thai fruits. Food Chem. 113: 202-207. Chen JP, Tai CY, Chen BH (2004). Improved liquid chromatographic method for determination of carotenoids in. Taiwanese mango (Mangifera indica L.) J. Chromatogr A. 1054(1-2): 261-268.

  19. A generalized solution to a Cahn-Hilliard/Allen-Cahn system

    Directory of Open Access Journals (Sweden)

    Jose Luiz Boldrini

    2004-10-01

    Full Text Available We study a system consisting of a Cahn-Hilliard and several Allen-Cahn type equations. This system was proposed by Fan, L.-Q. Chen, S. Chen and Voorhees for modelling Ostwald ripening in two-phase system. We prove the existence of a generalized solution whose concentration component is in $L^{infty}$.

  20. Quantum Fluctuations of Low Dimensional Bose-Einstein ...

    African Journals Online (AJOL)

    Tadesse

    underlying physics and to predict the possible applications in quantum information processing. Experiments which are recently conducted with ultracold bosons in optical resonators (Mekhov and Ritsch, 2009; Chen et al., 2007; Chen and Meystre, 2009; Marquardt and Girvin, 2009) unify nicely the above concepts.

  1. High School Students' Topic Preferences and Oral Development in an English-Only Short-Term Intensive Language Program

    Science.gov (United States)

    Hsieh, Hui-Chen

    2016-01-01

    Developing the ability to speak English is a daunting task that has long been omitted in a test-driven pedagogy context (Chang, 2011; Li, 2012a, 2012b; Chen & Tsai, 2012; Katchen, 1989, 1995). Since speaking is not tested for school admissions, most students are not motivated to learn it (Chang, 2011; Chen & Tsai, 2012). Now, globalization…

  2. Tropical Journal of Pharmaceutical Research - Vol 15, No 7 (2016)

    African Journals Online (AJOL)

    Methotrexate nanoparticle delivery system for treatment of inflammatory bowel disease in pediatric patients · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. Gang Liu, Dun-Chen Li, Ping-Ping Li, Ran-Ran Li, Shu-Ying Chen, 1361-1368.

  3. The antileishmanial agent licochalcone A interferes with the function of parasite mitochondria

    DEFF Research Database (Denmark)

    Zhai, L; Blom, J; Chen, M

    1995-01-01

    Our previous studies have shown that licochalcone A, an oxygenated chalcone, has antileishmanial (M. Chen, S.B. Christensen, J. Blom, E. Lemmich, L. Nadelmann, K. Fich, T.G. Theander, and A. Kharazmi, Antimicrob, Agents Chemother. 37:2550-2556, 1993; M. Chen, S.B. Christensen, T.G. Theander, and A...

  4. Replikation von µ-Peptidarrays

    OpenAIRE

    Striffler, Jakob

    2014-01-01

    In der vorliegen Arbeit wurde ein Verfahren erarbeitet und mit Photometrie, XPS und ToF-SIMS charakterisiert, mit dem durch mikropartikelbasierte Verfahren hergestellte µ-Peptidarrays von Syntheseoberflächen abgespalten und auf beliebige Zieloberflächen transferiert werden können.

  5. International Conference on the Science and Technology of Zirconia (ZrO2IV) (4th) Held in Anaheim, California on Nov 1-3, 1989

    Science.gov (United States)

    1990-02-01

    Y. Li, Y. Chilena de Energia Nuclear, Santiago Chen, W.E. Mayo and W. Roger Cannon*, Chile; I-Wei Chen, University of Michigan, Department of Material...Chilena de Energia Nuclear, Santiago, Chile. Composite samples were obtained Dy colloidal Y203-stabilized tetragonal zirconia poly- filtration of ZrO 2 /AL

  6. NEW ERBIUM DOPED ANTIMONY GLASSES FOR LASER AND ...

    African Journals Online (AJOL)

    2012-06-30

    Jun 30, 2012 ... glasses. The intensities of various absorption bands of the doped glasses are measured and the Judd-Ofelt parameters have been computed. From the ..... Chemistry of Rare Earth. 1998, 25. [2] Chen Y. J., Huang Y. D., Huang M. L., Chen R. P., Luo Z. D. Opt. Mater. 2004, 25,. 271. Transition λmax. Ar (s-1).

  7. Tropical Journal of Pharmaceutical Research - Vol 16, No 11 (2017)

    African Journals Online (AJOL)

    Correlation of expressions of S100A8 and S100A9 and its prognostic potential in nasopharyngeal carcinoma · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. Wenbing Hu, Gangsheng Wang, Lun Ye, Jun Chen, Xi Chen, Lei Gu, Zezhang Tao, 2577-2583 ...

  8. EAUROSURGERY

    African Journals Online (AJOL)

    radiographs to identify increase in size and intracranial extension. 41 6 Surgical excisions is necessary for symptomatic and giant cases. Recurrence is rare if excision is complete. References. 1. Chang SC, Chen PK, Chen YR, Chan. The Nigerian Journal of Surgical Research Volume 3 Number 3-4 December 2001 ...

  9. Invited Speaker Support for SBP Conference Series (SBP 2014) held in April, 2014 in Washington, DC.

    Science.gov (United States)

    2014-07-23

    Robin Baker and Paul Burns Break 9:30 AM Refreshments: muffins, bagels, hardcooked eggs, fruit, beverages Keynote 10:00 AM Keynote by...Emoticon Use in First and Second Languages Cecilia Aragon, Nan-Chen Chen, Judith Kroll and Laurie Feldman SBP Poster Social Maintenance and

  10. Expression of TLP-3 gene without signal peptide in tobacco plants ...

    African Journals Online (AJOL)

    Administrator

    2011-06-06

    Jun 6, 2011 ... For making the construction of pBI121 plasmid that have TLP-3 gene without signal peptide, plasmid was digested with Xba I ... coli XL1-Blue that has the construction, colony PCR and digesting were used. Tobacco transformation by ..... Plant pathology, 5th ed. Academic press. Chen WP, Chen PD, Liu DJ, ...

  11. DMPD: Antiviral innate immunity pathways. [Dynamic Macrophage Pathway CSML Database

    Lifescience Database Archive (English)

    Full Text Available 16474426 Antiviral innate immunity pathways. Seth RB, Sun L, Chen ZJ. Cell Res. 200...6 Feb;16(2):141-7. (.png) (.svg) (.html) (.csml) Show Antiviral innate immunity pathways. PubmedID 16474426 ...Title Antiviral innate immunity pathways. Authors Seth RB, Sun L, Chen ZJ. Publication Cell Res. 2006 Feb;16

  12. Developments in Microcomputing--Discovering New Opportunities for Libraries in the 1990s. Festschrift in Honour of Richard De Gennero. Papers presented at the International Essen Symposium (12th, Essen, West Germany, October 23-26, 1989).

    Science.gov (United States)

    Helal, Ahmed H., Ed.; Weiss, Joachim W., Ed.

    The 16 papers in this collection explore the microcomputer revolution as it affects library information systems: (1) "HyperMedia/Multimedia Technology and New Opportunities for Libraries in the 1990s" (Ching-chih Chen); (2) "Use of CD-ROMs in West German Libraries" (David I. Raitt and Ching-chih Chen); (3) "Purposes of Interactive Optical Discs…

  13. Anticancer Effects of Chenopodium ambrosiodes L. Essential Oil on ...

    African Journals Online (AJOL)

    168. 17. Hou J, Sun J, Chen SY, Chen S, Cai X, Zou G.. Chemical composition, cytotoxic and antioxidant activity of the leaf essential oil of Photinia serrulata. Food Chemistry 2007;. 103: 355-358. 18. Bezerra DP, Costa EV, Nogueira PCL.

  14. Rapid identification of the medicinal plant Taraxacum formosanum ...

    African Journals Online (AJOL)

    Rapid identification of the medicinal plant Taraxacum formosanum and distinguishing of this plant from its adulterants by ribosomal DNA internal transcribed spacer (ITS) based DNA barcode. YC Chiang, WT Chang, MD Chen, GH Lai, HJ Chen, J Chao, MK Lin, YS Chang, YM Chou, MS Lee, MS Lee ...

  15. Pitfalls in VAR based return decompositions: A clarification

    DEFF Research Database (Denmark)

    Engsted, Tom; Pedersen, Thomas Quistgaard; Tanggaard, Carsten

    Based on Chen and Zhao's (2009) criticism of VAR based return de- compositions, we explain in detail the various limitations and pitfalls involved in such decompositions. First, we show that Chen and Zhao's interpretation of their excess bond return decomposition is wrong: the residual component...

  16. The roles of electronic books in the transformation of learning and instruction

    NARCIS (Netherlands)

    Huang, R; Chen, N; Kang, M; McKenney, S; Churchill, D

    2014-01-01

    Huang, R., Chen, N., Kang, M. McKenney, S. & Churchill, D. (2013). The roles of electronic books in the transformation of learning and instruction. In N. Chen, R. Huang, Kinshuk, Y. Li, D. G. Sampson (Eds.) Proceedings of the IEEE 13th International Conference on Advanced Learning Technologies

  17. Antitumor activity of Scutellaria baicalensis Georgi total flavonoids ...

    African Journals Online (AJOL)

    ajl yemi

    2011-12-19

    Dec 19, 2011 ... Chang WH, Chen CH, Lu FJ (2002). Different effects of Baicalein,. Baicalin and Wogonin on mitochondrial function, glutathione content and cell cycle progression in human hepatoma cell lines. Planta Med. 68(2): 128-132. Du FY, Chen J, Ren XF (2008). Study on Extraction and Purification. Process of Total ...

  18. Anbautelegramm Lupinen (Lupinus angustifolius L., Lupinus luteus L., Lupinus albus L.)

    OpenAIRE

    Böhm, Herwart; Gruber, Harriet

    2013-01-01

    Für den Lupinenanbau werden in einem kurzgefassten Anbautelegramm die Stärken und Schwächen der weißen, gelben und blauen Lupinen sowie grundlegende Kennwerte zu Standortansprüchen, Aussaat, Unkrautregulierung, Nährstoffbedarf und Schaderregern dargestellt.

  19. Theoriebedingte Wörterbuchformprobleme und ...

    African Journals Online (AJOL)

    Wird sie erweitert, erkennt man im Licht der Theorie die Stärken und Schwächen der neuen Formelemente; das führt zur Wörterbuchkritik. Besonders die Schwächen führen zu wörterbuchformbedingten Benutzerproblemen. In diesem ersten Teil des Beitrags werden theoriebedingte Artikelformprobleme behandelt, die sich ...

  20. Theoriebedingte Wörterbuchform- probleme und wörterbuch ...

    African Journals Online (AJOL)

    Wird sie erweitert, erkennt man im Licht der Theorie die Stärken und Schwächen der neuen Formelemente; das führt zur Wörterbuchkritik. Besonders die Schwächen führen zu wörter- buchformbedingten Benutzerproblemen. In diesem ersten Teil des Beitrags werden theoriebedingte. Artikelformprobleme behandelt, die ...

  1. Li et al., Afr J Tradit Complement Altern Med. (2016) 13(2):61-71 http ...

    African Journals Online (AJOL)

    acer

    5 studies examined the effect of acupuncture combined with traditional Chinese drug, vs traditional Chinese drug (Chen et al., 2012; Chen and Le, 2005; Cheng, 2006; Liu, 2006; Zuo et al., 2004). 5 RCTs tested acupuncture combined with western medicine, vs western medicine (Ai et al., 2005; Li and Li, 2010; Ma and Li, ...

  2. to view fulltext PDF

    Indian Academy of Sciences (India)

    ... wave function: Fermion–scalar case and scalar–scalar case . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Chong Chen and Jiao-Kai Chen. 809. Cluster decay of 112−122Ba isotopes from ground state and as an excited compound system. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .K P Santhosh, P V Subha and B Priyanka.

  3. effect of pre-heattemperature onthetlglow curve offused

    African Journals Online (AJOL)

    offused quartz for dating and retrospective dosimetry applications (Chen and Mckeever, 1997; Pagonis et ... proposed by Chen and Mckeever (1994) was used: F(0kKkk M (1) where in the graph of TL versus dose, S., ... blackbody radiation from the sample holder. For each of the measurement reported, about 12 mg of the.

  4. Reference: 669 [Arabidopsis Phenome Database[Archive

    Lifescience Database Archive (English)

    Full Text Available psis. 21 3873-82 17933793 2007 Nov Development (Cambridge, England) Chen Jin-Gui|Chen Xiao-Ya|Ellis Brian E|Kwak Su-Hwan|Schiefelbein John|Wang Shucai|Zeng Qingning ... 669 http://metadb.riken.jp/db/SciNetS_ria224i/cria224u4ria224u17933793i Wang Shuca

  5. The Functional Unit of Japanese Word Naming: Evidence from Masked Priming

    Science.gov (United States)

    Verdonschot, Rinus G.; Kiyama, Sachiko; Tamaoka, Katsuo; Kinoshita, Sachiko; La Heij, Wido; Schiller, Niels O.

    2011-01-01

    Theories of language production generally describe the segment as the basic unit in phonological encoding (e.g., Dell, 1988; Levelt, Roelofs, & Meyer, 1999). However, there is also evidence that such a unit might be language specific. Chen, Chen, and Dell (2002), for instance, found no effect of single segments when using a preparation…

  6. Anti-Fatigue Effect of Aqueous Extract of Anisomeles indica (L ...

    African Journals Online (AJOL)

    Anti-Fatigue Effect of Aqueous Extract of Anisomeles indica (L) Kuntze in Mice. Chung-Shih Chen, Mei-Lin Wang, Rosa Huang Liu, Shih-Pin Chen, Tsong-Ming Lu, Wei-Yu Tsai, Chien-Fu Huang, Chi-Chiang Yang, Yew-Min Tzeng ...

  7. Influence of 1523 K annealing on phase and magnetic properties in ...

    Indian Academy of Sciences (India)

    1103–1108. c Indian Academy of Sciences. Influence of 1523 K annealing on phase and magnetic properties in. (Gd1−xErx)5Si2Ge2 compounds. XIANG CHEN1,2, YUNGUI CHEN1,∗ and YANGBO TANG1. 1School of Materials Science and Engineering, Sichuan University, Chengdu 610065, People's Republic of China.

  8. JPRS Report, Science & Technology, China, High-Power Laser and Particle Beams

    Science.gov (United States)

    1992-07-29

    Accelerator Conference, 1988. 12. Chen Jiaer, et al., "RF Superconducting Cavities at IHIP of Beijing University," to be published, 1990. 13. Chen...Jiaer, et al., IHIP Report SC-91-01, 1991. 21 14. Q.S. Shu, KEK Report 89-21, 1990, p 539. 15. R.W. Roth, et al., EPAC 90, Nice, 1990. 16. B. Byrns

  9. Research Paper ISSN 0189-6016©2008

    African Journals Online (AJOL)

    AJTCAM

    2008YB010). References. 1. Bocchini, P., Andalò, C., Pozzi, R., Galletti, G.C. and Antonelli, A. (2001). Determination of diallyl thiosulfinate (allicin) in garlic (Allium sativum L.) by high-performance liquid chromatography with a post-column photochemical reactor. Anal. Chim. Acta. 441: 37-43. 2. Chen, Y.C., Shen, S.C., Chen, ...

  10. Novel NPHS1 gene mutations in a Chinese family with congenital ...

    Indian Academy of Sciences (India)

    Department of Pediatrics, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology,. Wuhan, Hubei 430030, People's Republic of China. [Yang F., Chen Y., Zhang Y., Qiu L., Chen Y. and Zhou J. 2016 Novel NPHS1 gene mutations in a Chinese family with congenital nephrotic syndrome.

  11. Browse Title Index

    African Journals Online (AJOL)

    Items 101 - 150 of 1250 ... Vol 13, No 1 (2016), Activation of different cerebral functional regions following acupuncture at Bot H Taixi and Taichong acupoints and taixi acupointalone: An fMRI study, Abstract PDF. YJ Wanga, Y Zhenga, GF Zhang, JP Zhanga, CX Wua, SQ Zhang, HL Ouyang, ZP Li, JR Chen, SS Qu, JQ Chen, ...

  12. Journal of Astrophysics and Astronomy | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Astrophysics and Astronomy. Yang Chen. Articles written in Journal of Astrophysics and Astronomy. Volume 33 Issue 2 June 2012 pp 213-220. Star Formation Rate Indicators in Wide-Field Infrared Survey Preliminary Release · Fei Shi Xu Kong James Wicker Yang Chen Zi-Qiang Gong Dong-Xin ...

  13. Effects of Surface Treatment and Interfacial Strength on the Damage Propagation in Layered Transparent Armor under Impact

    Science.gov (United States)

    2011-03-20

    Confinement,” Experimental Mechanics, Vol. 36, pp. 155-158. Chen, W. and Zhang, X. (1997) “Dynamic response of Epon 828 /T-403 under multiaxial...B. (1998) “Constitutive behavior of Epon 828 /T403 at various strain rates,” Me- chanics of Time-Dependent Materials, Vol. 2, pp. 103-111. Chen, W

  14. Novel vitamin D 1α-hydroxylase gene mutations in a Chinese ...

    Indian Academy of Sciences (India)

    hydroxylase gene mutations in a Chinese vitamin-D-dependent rickets type I patient. Lihua Cao Fang Liu Yu Wang Jian Ma Shusen Wang Libo Wang Yang Zhang Chen Chen Yang Luo Hongwei Ma. Research Note Volume 90 Issue 2 August ...

  15. Production and characterization of heavy-metal removing bacterial ...

    African Journals Online (AJOL)

    DINESH

    2012-05-17

    May 17, 2012 ... 78: 967-973. He N, Li Y, Chen J, Lun SY (2002). Identification of a novel bioflocculant from a newly isolated Corynebacterium glutamicum. Biochem. Eng. J. 11: 137–148. He N, Li Y, Chen J (2004). Production of a novel polygalacturonic acid bioflocculant REA-11 by Corynebacterium glutamicum. Bioresour.

  16. Novel vitamin D 1α-hydroxylase gene mutations in a Chinese ...

    Indian Academy of Sciences (India)

    2011-08-19

    hydroxylase gene mutations in a Chinese vitamin-D-dependent rickets type I patient. LIHUA CAO1, FANG LIU2, YU WANG1, JIAN MA2, SHUSEN WANG1, LIBO WANG2, YANG ZHANG1,. CHEN CHEN1, YANG LUO1∗ and HONGWEI ...

  17. Pramana – Journal of Physics | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Pramana – Journal of Physics. BINGYAN CHEN. Articles written in Pramana – Journal of Physics. Volume 89 Issue 3 September 2017 pp 37 Research Article. Graphene-based tunable terahertz filter with rectangular ring resonator containing double narrow gaps · WEI SU BINGYAN CHEN · More Details ...

  18. Influence of 1523 K annealing on phase and magnetic properties in ...

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science; Volume 34; Issue 5. Influence of 1523 K annealing on phase and magnetic properties in (Gd1−Er)5Si2Ge2 compounds. Xiang Chen Yungui Chen Yangbo Tang. Volume 34 Issue 5 August 2011 pp 1103-1108 ...

  19. Nociceptor Response - A Review of Literature

    Science.gov (United States)

    2015-02-20

    fibers are recruited (Sikandar et al., 2013; Arendt -Nielsen & Bjerring, 1988a; Pertovaara et al., 1988). Increased heating rate results in increased...thermal stimulation with contact heat from thermodes or radiant heat from a light bulb proved to have many limitations ( Arendt -Nielsen & Chen, 2003...can be further classified as mechanoreceptors, chemoreceptors, mechanoinsensitive nociceptors, and polymodal nociceptors ( Arendt -Nielsen & Chen, 2003

  20. Evaluation of NF-kappaB Signaling in T Cells

    Science.gov (United States)

    2009-01-01

    M. Blonska, H. Li, M. Kobayashi, B. Pappu , Y. Chen, D. Wang, and X. Lin. 2005. Phosphorylation of CARMA1 plays a critical role in T Cell receptor...receptor signaling to nu- clear factor B. Immunity 25: 701–715. 4. Matsumoto, R., D. Wang, M. Blonska, H. Li, M. Kobayashi, B. Pappu , Y. Chen, D. Wang, and