Search for wrong-sign D0 decays

International Nuclear Information System (INIS)

Abachi, S.; Baringer, P.; Bylsma, B.G.; Debonte, R.; Koltick, D.; Loeffler, F.J.; Low, E.H.; McIlwain, R.L.; Miller, D.H.; Ng, C.R.; Shibata, E.I.; Akerlof, C.; Chapman, J.; Errede, D.; Meyer, D.I.; Nitz, D.; Seidl, A.; Thun, R.; Blockus, D.; Brabson, B.; Brom, J.M.; Ogren, H.; Rust, D.R.; Snyder, A.; Cork, B.; Derrick, M.; Kooijman, P.; Musgrave, B.; Price, L.E.; Repond, J.; Sugano, K.; Gan, K.K.; Jung, C.; Kesten, P.; Loos, J.S.; Rangan, L.K.; Wood, D.E.; Weiss, J.M.

1986-01-01

Using a data sample corresponding to an integrated luminosity of 300 pb -1 obtained at PEP with the High Resolution Spectrometer, the wrong-sign decay D 0 →K + π - has been searched for using a sample of D * →D 0 π events. A 4% upper limit is obtained at the 90% confindence level for the ratio of the wrong sign to the right sign decay rate in the Kπ mode. (orig.)

What's Wrong with Economics Textbooks?

Science.gov (United States)

Culyer, A. J.

1985-01-01

Many things are wrong with college level economics textbooks. For example, they are too ahistorical, too particularist, or unsystematically eclectic. The requirements of a good college economics textbook are examined. (RM)

Experiment, right or wrong

CERN Document Server

Franklin, Allan

2008-01-01

In Experiment, Right or Wrong, Allan Franklin continues his investigation of the history and philosophy of experiment presented in his previous book, The Neglect of Experiment. In this new study, Franklin considers the fallibility and corrigibility of experimental results and presents detailed histories of two such episodes: 1) the experiment and the development of the theory of weak interactions from Fermi's theory in 1934 to the V-A theory of 1957 and 2) atomic parity violation experiments and the Weinberg-Salam unified theory of electroweak interactions of the 1970s and 1980s. In these episodes Franklin demonstrates not only that experimental results can be wrong, but also that theoretical calculations and the comparison between experiment and theory can also be incorrect. In the second episode, Franklin contrasts his view of an "evidence model" of science in which questions of theory choice, confirmation, and refutation are decided on the basis of reliable experimental evidence, with that proposed by the ...

Separation process of zirconium and hafnium; Procede de separation du zirconium et du hafnium

Energy Technology Data Exchange (ETDEWEB)

Hure, J; Saint-James, R [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

1955-07-01

About the separation different processes of zirconium-hafnium, the extraction by solvent in cross-current is the most easily the process usable on an industrial scale. It uses tributyl phosphate as solvent, diluted with white spirit to facilitate the decanting. Some exploratory tests showed that nitric environment seemed the most favorable for extraction; but a lot of other factors intervene in the separation process. We studied the influence of the acidity successively, the NO{sub 3}{sup -} ions concentration, the role of the cation coming with NO{sub 3}{sup -}, as well as the influence of the concentration of zirconium in the solution on the separation coefficient {beta} = {alpha}{sub Zr} / {alpha}{sub Hf}. (M.B.) [French] Des differents procedes de separation zirconium-hafnium, l'extraction par solvant en contre-courant est le procede le plus facilement utilisable a l'echelle industrielle. On utilise comme solvant le phosphate de tributyle, dilue avec du white spirit pour faciliter les decantations. Des essais preliminaires ont montre que le milieu nitrique semblait le plus favorable a l'extraction; mais beaucoup d'autres facteurs interviennent dans le processus de separation. Nous avons etudie successivement l'influence de l'acidite, celle de la concentration en ions NO{sub 3}{sup -}, le role du cation accompagnant NO{sub 3}{sup -}, ainsi que l'influence de la concentration en zirconium de la solution sur le coefficient de separation {beta} = {alpha}{sub Zr} / {alpha}{sub Hf}. (MB)

Broadening the future of value account of the wrongness of killing

DEFF Research Database (Denmark)

Di Nucci, Ezio

2015-01-01

On Don Marquis's future of value account of the wrongness of killing, 'what makes it wrong to kill those individuals we all believe it is wrong to kill, is that killing them deprives them of their future of value'. Marquis has recently argued for a narrow interpretation of his future of value...... account of the wrongness of killing and against the broad interpretation that I had put forward in response to Carson Strong. In this article I argue that the narrow view is problematic because it violates some basic principles of equality and because it allows for some of the very killing that Marquis...

Lessons learned: wrong intraocular lens.

Science.gov (United States)

Schein, Oliver D; Banta, James T; Chen, Teresa C; Pritzker, Scott; Schachat, Andrew P

2012-10-01

To report cases involving the placement of the wrong intraocular lens (IOL) at the time of cataract surgery where human error occurred. Retrospective small case series, convenience sample. Seven surgical cases. Institutional review of errors committed and subsequent improvements to clinical protocols. Lessons learned and changes in procedures adapted. The pathways to a wrong IOL are many but largely reflect some combination of poor surgical team communication, transcription error, lack of preoperative clarity in surgical planning or failure to match the patient, and IOL calculation sheet with 2 unique identifiers. Safety in surgery involving IOLs is enhanced both by strict procedures, such as an IOL-specific "time-out," and the fostering of a surgical team culture in which all members are encouraged to voice questions and concerns. Copyright © 2012 American Academy of Ophthalmology. Published by Elsevier Inc. All rights reserved.

WRONGFUL TRADING: COMPARATIVE APPROACH (ENGLAND AND WALES, RUSSIA AND THE USA

Directory of Open Access Journals (Sweden)

D. Konstantinov

2015-01-01

Full Text Available This paper is designed to discover legal rules addressing insolvency trading in three jurisdictions: England and Wales, Russia and the USA. Originally it was a master’s dissertation written under supervision of Ms. Sarah Paterson, who was extremely helpful and patient. The key jurisdiction for the research is England and Wales, whose wrongful trading provision apparently was the very first insolvency regulation in the field. Here, we will give particular attention to the factual circumstances of insolvency trading and research how the concept of wrongful trading addresses them. The next question will be how the American concept of deepening insolvency and the Russian concept of subsidiary liability are comparable with wrongful trading. Later, we will focus on the functions that should be performed by the regulations. Also, the effectiveness of wrongful trading and similar overseas provisions will be examined. Finally, this paper attempts to find obstacles to the wide application of wrongful trading provision.

Where physics went wrong

CERN Document Server

Lavenda, Bernard

2015-01-01

The book points out what has gone wrong with physics since Einstein's formulation of this theory of general relativity a century ago. It points out inconsistencies and fallacies in the standard model of the big bang and the inflationary scenario which was supposed to have overcome those shortcomings, the evolution of string theory from a theory of the strong interaction to a theory of gravitation and quantum mechanics which has not produced a single verifiable prediction, and what it has accomplished is reaffirming wrong results like the entropy of a black hole, which is not an entropy at all. There have even been attempts to demote gravity to an emergent phenomenon with catastrophic effects. We know exactly what happened at 10-34 seconds after the big bang, but do not know how fast gravity propagates, whether gravitational waves exist, and what are the limits of Newton's law. Attempts to rectify this are the prediction of dark energy/matter, which has never been observed nor ever will, and MOND. The latter i...

Wrong vertex displacements due to Lee-Wick resonances at LHC

International Nuclear Information System (INIS)

Alvarez, E.; Schat, C.; Rold, L. da; Szynkman, A.

2009-01-01

We show how a resonance from the recently proposed Lee-Wick Standard Model could lead to wrong vertex displacements at LHCb. We study which could be the possible 'longest lived' Lee-Wick particle that could be created at LHC, and we study its possible decays and detections. We conclude that there is a region in the parameter space which would give wrong vertex displacements as a unique signature of the Lee-Wick Standard Model at LHCb. Further numerical simulation shows that LHC era could explore these wrong vertex displacements through Lee-Wick leptons below 500 GeV. (author)

Application of human error theory in case analysis of wrong procedures.

Science.gov (United States)

Duthie, Elizabeth A

2010-06-01

The goal of this study was to contribute to the emerging body of literature about the role of human behaviors and cognitive processes in the commission of wrong procedures. Case analysis of 5 wrong procedures in operative and nonoperative settings using James Reason's human error theory was performed. The case analysis showed that cognitive underspecification, cognitive flips, automode processing, and skill-based errors were contributory to wrong procedures. Wrong-site procedures accounted for the preponderance of the cases. Front-line supervisory staff used corrective actions that focused on the performance of the individual without taking into account cognitive factors. System fixes using human cognition concepts have a greater chance of achieving sustainable safety outcomes than those that are based on the traditional approach of counseling, education, and disciplinary action for staff.

Teacher Professionalism: The Wrong Conversation.

Science.gov (United States)

Coulter, David; Orme, Liz

2000-01-01

Defining teachers as professionals in the same way that doctors or engineers are professionals is reductionist because such definition generally distorts the moral dimensions of teaching by using the wrong language (clients, customers), focusing on limited forms of knowledge, and ignoring the fundamental democratic character of education.…

Does Wrongful Conviction Lower Deterrence?

DEFF Research Database (Denmark)

Lando, Henrik

2004-01-01

lowerthe threat of being sanctioned for a crime one commits, if two sanctions are not twiceas threatening as one. Second, if wrongful conviction halts further investigations thatmay lead to the true offender, and third, if a potential offender thinks that if he or shedoes not take advantage of a crime...

Search for wrong sign D0 decays with the HRS detector

International Nuclear Information System (INIS)

Abachi, S.; Akerlof, C.; Barringer, P.

1986-01-01

Using a data sample corresponding to an integrated luminosity of 300pb -1 obtained at PEP with the HRS detector we have searched for the wrong sign decay of D 0 mesons in the decays D* → D 0 π. We obtain a 90% confidence level limit of 4.0% on the ratio of the wrong sign to the right sign decay rate in the Kπ mode. This is the best model independent limit on mixing currently available and constrains the nature of the wrong sign signal recently reported by the MARK III group. 10 refs., 2 figs

Liability for wrongful terminations: are hospitals at risk?

Science.gov (United States)

Hames, D S

1991-01-01

This article examines the extent to which the three principal exceptions to the common-law doctrine of employment-at-will--namely the public policy, implied contract, and good faith and fair dealing exceptions--have been recognized in hospital termination cases. State supreme court and appellate court cases are analyzed to illustrate the type of conduct that precipitated wrongful termination claims against hospitals during the 1980s, how the courts disposed of these claims, and the rationale underlying their decisions. Suggestions, based on these and related cases, for avoiding or at least minimizing liability for wrongfully terminating hospital employees, are presented.

Wrong signals

International Nuclear Information System (INIS)

Nillesen, P.H.L.; Telling, J.G.

2001-01-01

The Netherlands Electricity Regulatory Service (Dte, abbreviated in Dutch) bases the determination of the efficiency of electricity network businesses on the possibility of businesses to adjust their production capacity on a short term. In reality, however, the production capacity of electricity networks is fixed. By adjusting the model, by means of which the efficiency is determined, to the assumption of Dte, other efficiency scores will be produced. As a result of the output of the present model, many businesses receive the wrong stimuli. In this article the method of Dte is assessed. By putting the method in an international context it is determined whether the aim of the regulation is realized. The production process of the Dutch market is specified and compared internationally.1 ref

The concept of wrongful life in the law.

Science.gov (United States)

Kasper, A S

1983-01-01

In the history of the law the concept of wrongful life is not new, but it has become of interest recently due to changing social attitudes and advances in contraceptive and genetic technologies. This discussion tries to assess the effects of wrongful life as a legal concept on the rights of childbearing women and their offspring. An unborn child had no rights under common law, which held that a fetus in utero had no existence separate from its mother. Consequently, a child had no right of action for personal harm brought upon it by another person. On occasion early courts disagreed with this view, but the majority of courts maintained that a child had no existence as a human being during gestation. The effect that this concept of common law would have on current abortion laws would be to make it considerably easier to argue for a woman's right to choose an abortion. The notion of wrongful life initially appeared in cases of illegitimate births. In Zepeda v. Zepeda, 1963, and Williams v. State of New York, 1966, the plaintiffs maintained that the children's births and existence were wrongful because they were unintended and illegitimate. In Williams the court ruled that birth under 1 set of circumstances and not another is not a recoverable injury. These cases failed to meet the requirements of tort law, and the court rejected the notion of children finding legal recourse for being born to a poor family or being born to a less desired race or class. A series of cases followed in which recovery for physical injury or birth deformities were claimed by parents for themselves and their children. In June 1980 a California appeals court reversed the decision of a lower court, addressing the fundamental principles of wrongful life as a legal concept. In Curlender v. Bio-Science Laboratories an infant brought suit alleging that the laboratories failed to correctly inform her parents of their status as carriers of Tay-Sachs disease during the mother's pregnancy. The infant

7 CFR 1.51 - Claims based on negligence, wrongful act or omission.

Science.gov (United States)

2010-01-01

... 7 Agriculture 1 2010-01-01 2010-01-01 false Claims based on negligence, wrongful act or omission. 1.51 Section 1.51 Agriculture Office of the Secretary of Agriculture ADMINISTRATIVE REGULATIONS Claims § 1.51 Claims based on negligence, wrongful act or omission. (a) Authority of the Department...

When experiments go wrong: the U.S. perspective.

Science.gov (United States)

Capron, Alexander M

2004-01-01

The view that once prevailed in the U.S.--that research is no more dangerous than the activities of daily life--no longer holds in light of recent experience. Within the past few years, a number of subjects (including normal volunteers) have been seriously injured or killed in research conducted at prestigious institutions. Plainly, when we are talking about research going wrong, we're talking about something very important. We have seen that experiments can go wrong in several ways. Subjects can be injured--physically, mentally, or by having other interests violated. Investigators can commit fraud in data collection or can abuse subjects. And review mechanisms--such as IRBs--don't always work. The two major issues when research goes wrong in any of these ways are, first: What will be done for subjects who have suffered an injury or other wrong? and second: How will future problems be prevented? The present system in the U.S. is better at the second task than the first one. Part of the difficulty in addressing the first lies in knowing what "caused" an apparent injury. Moreover, since until recently the problem of research-related injuries was thought to be a small one, there was considerable resistance to setting up a non-fault compensation system, for fear that it would lead to payment in many cases where such compensation was not deserved. Now, with a further nudge from the NBAC there is renewed interest in developing a formal system to compensate for research injuries. Finally, I have tried to show that our system of local oversight is only partially effective in improving the design of experiments and the consent process in light of "unexpected (adverse) results." As many observers, including the federal General Accounting Office (GAO), have reported, the requirement for "continuing review" of approved research projects is the weak point in the IRB system. The probable solution would be to more strictly apply the requirement that investigators report back any

The resin-in-pulp process and its application to ores from Brosses ''BRS 10''; Le procede resin in pulp et son application aux minerais des Brosses ''BRS 10''

Energy Technology Data Exchange (ETDEWEB)

Kremer, M

1959-03-01

The resin-in-pulp process is a technical variant of the recovery process of uranium in dilute solution by means of ion exchanger resins. An anion resin, XE 123, of a well-defined grain size is placed in direct contact with the pulp produced by sulfuric acid attack on ore with a low uranium content. This process is of particular value in the treatment of pulps that cannot be filtered or decanted, such as those obtained with ore from Brosses. The preparation of the pulp, the elution of the uranium, and its fixation, as well as the various factors encountered in these operations, are discussed. (author) [French] Le procede ''resin in pulp'' est une variante technique du procede de recuperation de l'uranium en solution diluee par les resines echangeuses d'ions. Une resine anionique, la 'XE 123' a granulometrie bien determinee, est mise en contact direct avec la pulpe provenant de l'attaque a l'acide sulfurique d'un minerai d'uranium a faible teneur. Ce procede est particulierement interessant dans le cas de pulpes infiltrables ou indecantables, telles que celles obtenues dans l'attaque du minerai des Brosses. La preparation de la pulpe, la fixation et l'elution de l'uranium, ainsi que les facteurs intervenant dans ces diverses operations sont etudies dans le present rapport. (auteur)

The Use and Influence of Comparative Law in ‘Wrongful Life’ Cases

Directory of Open Access Journals (Sweden)

Ivo Giesen

2012-05-01

Full Text Available In analysing 'wrongful life' cases, comparative law is used extensively. This article examines these wrongful life cases, especially in light of the contradicting outcomes in different jurisdictions across the world, with the Dutch Kelly case and the South African decision in Stewart v Botha as its main examples. I will test the hypothesis that it is not so much the outcomes and (more importantly the arguments found elsewhere through the comparative law method that are decisive in highly debated cases like those concerning wrongful life, but that instead it is something else that decides the issue, something I would define as the cultural background of, or the legal policies within a tort law system.

Psychopaths know right from wrong but don’t care

Science.gov (United States)

Tonnaer, Franca; Hauser, Marc D.

2010-01-01

Adult psychopaths have deficits in emotional processing and inhibitory control, engage in morally inappropriate behavior, and generally fail to distinguish moral from conventional violations. These observations, together with a dominant tradition in the discipline which sees emotional processes as causally necessary for moral judgment, have led to the conclusion that psychopaths lack an understanding of moral rights and wrongs. We test an alternative explanation: psychopaths have normal understanding of right and wrong, but abnormal regulation of morally appropriate behavior. We presented psychopaths with moral dilemmas, contrasting their judgments with age- and sex-matched (i) healthy subjects and (ii) non-psychopathic, delinquents. Subjects in each group judged cases of personal harms (i.e. requiring physical contact) as less permissible than impersonal harms, even though both types of harms led to utilitarian gains. Importantly, however, psychopaths’ pattern of judgments on different dilemmas was the same as those of the other subjects. These results force a rejection of the strong hypothesis that emotional processes are causally necessary for judgments of moral dilemmas, suggesting instead that psychopaths understand the distinction between right and wrong, but do not care about such knowledge, or the consequences that ensue from their morally inappropriate behavior. PMID:20053752

The Growing Acknowledgement of Wrongful Conviction – The Australian Response Within an International Context

Directory of Open Access Journals (Sweden)

Lynne Weathered

2013-12-01

Full Text Available The wrongful conviction of innocent people is being acknowledged in an increasing number of countries around the world. The problem of wrongful conviction is now framed as an international human rights issue. More attention is being given to whether criminal justice systems are providing sufficient measures for the effective review and rectification of wrongful convictions and whether international obligations in that regard are being met. England, Wales, Northern Ireland, Scotland, Norway, Canada and the United States have substantial new mechanisms in place to better identify and correct wrongful convictions but Australia has been slower to respond. While some Australian states have introduced reforms such as DNA innocence testing and a new appeal avenue, many issues remain as highlighted in recent debates as to whether Australia should establish a Criminal Cases Review Commission.

Impact of reflective writing assignments on dental students' views of cultural competence and diversity.

Science.gov (United States)

Isaac, Carol; Behar-Horenstein, Linda; Lee, Barbara; Catalanotto, Frank

2015-03-01

To respond to widespread disparities in access to oral health care, the Institute of Medicine, the Commission on Dental Accreditation (CODA), and the U.S. surgeon general have stressed that prospective dentists should become culturally competent, socially responsible practitioners. The aim of this study was to examine linguistic differences in dental students' reflective writing assignments before and after interviewing an individual who was culturally different from themselves. The authors analyzed 160 documents from 80 first-year dental students at the University of Florida in 2012. This cohort consisted of 36 male (45%) and 44 female (55%) students; 26 (32%) were from underrepresented minority (URM) groups and 54 (68%) were identified as white non-minority. Text analysis software identified word counts, categories, frequencies, and contexts. Significantly positive differences occurred for interviews between assignments 1 and 2 (p=0.005 to pcultural diversity. Differences were observed for Factor 1 ("important others' influence") between assignments (p<0.001), assignments by interview categories (p=0.033), and URM/majority participants by assignments by interview category (p=0.018). Factor 4 ("my social world in relation to others") was statistically different between assignments for URM/majority participants (p=0.019). Factor 5 ("wrong because") was statistically different for gender (p=0.041), suggesting that males may have experienced a rebound effect from stereotype suppression. The findings suggest that the use of reflective writing and interviews affected the students' awareness of how important others had influenced their lives and attitudes and facilitated their questioning preconceived assumptions. Reactions to coursework focusing on social and personal domains warrant further investigation.

Legal liability for failure to prevent pregnancy (wrongful pregnancy

Directory of Open Access Journals (Sweden)

Lodewicus Charl Coetzee

2017-05-01

Full Text Available Can the conception of a child ever constitute damage recoverable in law? This article considers the liability of healthcare practitioners for failing to prevent a pregnancy. Developments leading to the recognition of wrongful pregnancy as a cause of (legal action in South Africa (SA, are briefly outlined. The salient points of the relevant judgments by SA courts are set out to expose the rationale underlying the judgments and to highlight that recognition of liability for wrongful pregnancy resulted from an application of fair and equitable principles of general application. Conduct that could expose practitioners to liability is identified from reported cases and inferred from general principles laid down in case law.

SEPA (Service d'etudes, de Procedes et Analyses)

International Nuclear Information System (INIS)

2017-01-01

The SEPA (Service d'etudes, de Procedes et Analyses), is an engineering department specializing in the analysis and processing of uranium ore. It comes from a long tradition of mining in France that began sixty-five years ago with the French Atomic Energy Commission (CEA) and that has been carried on by COGEMA and then Areva. SEPA brings a combination of experience and excellence to its activities thanks to its multidisciplinary staff (mineralogists, chemists, mechanical engineers, instrumentation specialists...), who come from diverse cultural backgrounds. Today, the SEPA draws on its wealth of know-how and expertise to devise and develop new methods for processing and valorizing ores everywhere in the world. Its mission is to: - Develop and conduct laboratory tests on methods for processing uranium and other valuable elements such as molybdenum, vanadium, rare earths, niobium, tantalum and thorium; - Analyze ores obtained during prospecting at locations all over the world; -Serve as an advisor in the commissioning of Areva industrial units and ore processing plants; -Perform environmental analyses during the full period of mining operations; -Conduct audits and provide advice on processes and analysis methods; -Carry out research and development in all aspects of minerals treatment (including the filing of patents). The SEPA combines experience, skills and a global approach to technologies used in ore processing. Its role is to continually improve the processes for extracting, processing and valorizing ores while protecting the environment

Energy policy - way out and wrong way

International Nuclear Information System (INIS)

Anon.

1989-01-01

The way out, i.e. the right solution of the energy supply problem, is solar energy. The wrong way are high-temperature reactors and nuclear fusion. Arguments are put forward that nuclear fusion, considered an alternative to the harmful nuclear fission even by some nuclear opponents, is in fact equally harmful. (qui)

UNA MIRADA A LAS TENDENCIAS Y LOS RETOS DEL VOLUNTARIADO PROCEDER

Directory of Open Access Journals (Sweden)

Andrea Rivera Duque

2016-12-01

Full Text Available Hoy día, las personas buscan aprovechar su tiempo libre en actividades solidarias. Una de las opcionespor las que más a menudo se inclinan son los voluntariados, tal como se señala en el Informe sobre el estado del voluntariado en el mundo para 2011, de las Naciones Unidas. La poca información concreta y disponible, así como la escasez de referentes acerca del voluntariado tanto a escala nacional como desde el ámbito universitario, es el aspecto más notorio a la hora de hacer un análisis de la realidad de este tipo de movimientos. Pese a ello, algunas fuentes rigurosas y actualizadas nos permiten aproximarnos a esta realidad e identificar algunos de los retos y las tendencias que deben plantearse en dicho ámbito para su futuro. El objetivo de la presente revisión bibliográfica es conocer el estado actual de la realidad de los voluntariados universitarios tomando en cuenta los ámbitos de carácter internacional y nacional, para, con ello, orientar mejor la experiencia extracurricular que se ha hecho con el voluntariado Proceder , del Programa Ciencias del Deporte y la Recreación de la Universidad Tecnológica de Pereira.

Particle Swarm Optimization Algorithm for Optimizing Assignment of Blood in Blood Banking System

Science.gov (United States)

Olusanya, Micheal O.; Arasomwan, Martins A.; Adewumi, Aderemi O.

2015-01-01

This paper reports the performance of particle swarm optimization (PSO) for the assignment of blood to meet patients' blood transfusion requests for blood transfusion. While the drive for blood donation lingers, there is need for effective and efficient management of available blood in blood banking systems. Moreover, inherent danger of transfusing wrong blood types to patients, unnecessary importation of blood units from external sources, and wastage of blood products due to nonusage necessitate the development of mathematical models and techniques for effective handling of blood distribution among available blood types in order to minimize wastages and importation from external sources. This gives rise to the blood assignment problem (BAP) introduced recently in literature. We propose a queue and multiple knapsack models with PSO-based solution to address this challenge. Simulation is based on sets of randomly generated data that mimic real-world population distribution of blood types. Results obtained show the efficiency of the proposed algorithm for BAP with no blood units wasted and very low importation, where necessary, from outside the blood bank. The result therefore can serve as a benchmark and basis for decision support tools for real-life deployment. PMID:25815046

Particle swarm optimization algorithm for optimizing assignment of blood in blood banking system.

Science.gov (United States)

Olusanya, Micheal O; Arasomwan, Martins A; Adewumi, Aderemi O

2015-01-01

This paper reports the performance of particle swarm optimization (PSO) for the assignment of blood to meet patients' blood transfusion requests for blood transfusion. While the drive for blood donation lingers, there is need for effective and efficient management of available blood in blood banking systems. Moreover, inherent danger of transfusing wrong blood types to patients, unnecessary importation of blood units from external sources, and wastage of blood products due to nonusage necessitate the development of mathematical models and techniques for effective handling of blood distribution among available blood types in order to minimize wastages and importation from external sources. This gives rise to the blood assignment problem (BAP) introduced recently in literature. We propose a queue and multiple knapsack models with PSO-based solution to address this challenge. Simulation is based on sets of randomly generated data that mimic real-world population distribution of blood types. Results obtained show the efficiency of the proposed algorithm for BAP with no blood units wasted and very low importation, where necessary, from outside the blood bank. The result therefore can serve as a benchmark and basis for decision support tools for real-life deployment.

Desalting of sea water by a wall-less evaporation process; Dessalement de l'eau de mer par un procede d'evaporation sans paroi

Energy Technology Data Exchange (ETDEWEB)

Kassel, C; Sachine, P; Vuillemey, R [Commissariat a l' Energie Atomique, Centre d' Etudes Nucleaires de Saclay, 91 - Gif-sur-Yvette (France)

1966-06-01

The need for fresh water supplies in many parts of the globe has given a great impetus to the study of the desalting of sea-water. Research into this problem has been very varied. Although it is possible in the more-or-less near future that methods based on freezing may be developed, only evaporation methods have industrial applications at the present time. Amongst the many techniques using this method, the most favorably placed installations from the technical and economic points of view are those based on multiple effects and wall-less heat transfer. We have defined the characteristics of a wall-less evaporation process using the various factors involved in this evaporation: energy source, corrosion, furring, heat transfer, maximum temperature, etc... The unit considered in this work has a daily output of 100,000 m{sup 3}, and makes use of the multi-stage technique with an organic heat-carrier. The maximum temperature of the first stage is 150 deg C and the evaporation factor is 0.4. After the description of the process and, the calculation of the equipment, an economic estimate is given of the cost-price : 1.49 F/m{sup 3}. It is likely that more detailed study of the process (technique, equipment and energy consumed) should make it possible to obtain a significant improvement in the process and to reduce the price to 1 F/m{sup 3}. (authors) [French] Le probleme de l 'approvisionnement en eau de nombreuses regions du globe a mis a 1'ordre du jour le dessalement de l'eau de mer. Des recherches sur cette question ont ete faites dans de multiples directions. Si dans un avenir plus ou moins proche les procedes par congelation peuvent se developper, actuellement seules les methodes d'evaporation ont des applications industrielles. Parmi les nombreuses techniques qui visent a mettre en oeuvre ce principe, les installations a multiples effets et transfert de chaleur sans paroi semblent les mieux placees du point de vue technique et economique. A partir des divers

What if physics is wrong?

Science.gov (United States)

Tu, Zhoudunming

2011-11-01

Physics, an experiment-based science, seems to be the most appropriate subject in how to explain the inner workings of the world. We respect physics because it is based on facts that are perceived by our observations. However, what if we are not seeing the entire truth we seek? What if our observations are founded on sandy foundations? As humans, we desire to know what the truth is. Rene Descartes, a mathematician, philosopher, and physicist asked this question: what is the absolute truth in our universe? I want to solve the same puzzle. Many people believe that physics will reveal the truth of our universe. But, what if physics is wrong?

B decays to wrong sign charm mesons at the DELPHI experiment

International Nuclear Information System (INIS)

Schwanda, C.

2001-05-01

In the present work, b hadron decays to 'wrong sign charm' mesons, b → D-bar 0 X, b → D - X and b → D s - X, are studied using the data collected by the DELPHI experiment in the years 1994 and 1995, and the corresponding branching fractions are extracted. Decays b → c-bar are expected to occur through the Cabibbo favored transitions b → cW - and W - → cbar s, and hence wrong sign charm decays are in fact double charm transitions. The interest in this type of b decays is triggered by different motivations. At first, wrong sign charm decays provide evidence for an alternative mechanism leading to the production of charmed mesons in b decay ('upper vertex charm'), and, second, the double charm rate is related to n c , the mean number of charm quarks (and anti-quarks) produced per b decay, n c =1 + Br(b → c c-bar s). Predictions of the semileptonic B meson branching fraction, based on the heavy quark effective theory (HQET) and the heavy quark expansion (HQE), also fix the value of n c . By measuring the double charm rate, we can thus probe these predictions. The measurement of the inclusive wrong sign branching fractions proceeds through the following steps: At first, the charmed meson decays D 0 → K - π + , D + → K - π + π + and D s + → φ π + → K + K - π + are exclusively reconstructed in the DELPHI data. The charge of the c quark confined inside the charmed meson is determined by the charge of the kaon (D 0 , D + ) or by the charge of the pion (D s + ). The b quark charge at decay time in the charmed meson hemisphere is estimated by using identified particles. A neural network approach is adopted. By correlating both charge informations, we obtain the main discriminant variable for selecting wrong sign mesons. We measure the following branching ratios: Br(b → D-bar X)=(9.3 ± 1.7(stat) ± 1.3(syst))% and Br(b → D s - X)=(10.3 ± 1.1(stat) ± 2.9(syst))% (the first error is statistical, the second one systematic). This result is

Transformations of highly enriched uranium into metal or oxide; Etudes des procedes de transformation des composes d'uranium a fort enrichissement isotopique

Energy Technology Data Exchange (ETDEWEB)

Nollet, P; Sarrat, P [Commissariat a l' Energie Atomique, Fontenay-aux-Roses (France). Centre d' Etudes Nucleaires

1964-07-01

described successively, together with the studies which led to their development The civil engineering construction was begun in June 1962. The workshops are to start production in may 1964. (authors) [French] Les ateliers de traitement d'uranium enrichi de Cadarache ont pour but: d'une part, de transformer l'hexafluorure d'uranium en metal, ou en oxyde, et d'autre part, de recuperer l'uranium contenu dans les dechets divers produits lors des operations de transformation metallurgique. Les principes qui ont ete suivis pour la conception et la securite de ces ateliers sont exposes. La securite nucleaire est basee sur la geometrie des appareils de traitement. Pour mettre au point les procedes et la technologie de ces ateliers, de nombreuses etudes ont ete conduites depuis 1960, dont certaines ont abouti a des realisations originales. La transformation de l'hexafluorure d'uranium a fort enrichissement isotopique s'effectue, soit par injection en phase gazeuse dans l'ammoniaque, soit par un procede original de reduction directe en tetrafluorure d'uranium par l'hydrogene. La recuperation de l'uranium contenu dans les dechets metalliques d'uranium-zirconium s'operera par attaque par l'acide chlorhydrique, puis traitement du chlorure d'uranium par le fluor afin d'obtenir l'uranium sous forme d'hexafluorure. La recuperation de l'uranium contenu dans les dechets divers s'opere par un procede classique de raffinage: grillage des dechets metalliques, dissolution de l'oxyde obtenu dans l'acide nitrique, purification par solvant au tributyl-phosphate, precipitation a l'ammoniaque, calcination reduction fluoruration, calciothermie et traitement des scories. Deux ateliers separes fonctionnent suivant ce procede: l'un traite l'uranium d'un enrichissement isotopique inferieur ou egal a 3 p. 100, l'autre est reserve aux forts enrichissements. La mise en oeuvre, d'une maniere nucleairement sure, de chacune des etapes du procede a pose des problemes technologiques particuliers et a conduit a

Identifying wrong assemblies in de novo short read primary

Indian Academy of Sciences (India)

Finally, some mis-assembly detecting tools have been evaluated for their ability to detect the wrongly assembledprimary contigs, suggesting a lot of scope for improvement in this area. The present work also proposes a simpleunsupervised learning-based novel approach to identify mis-assemblies in the contigs which was ...

Some physical methods for study of irradiation effects in graphite; Quelques procedes physiques pour etudier les effets de l'irradiation du graphite

Energy Technology Data Exchange (ETDEWEB)

Mayer, G; Lecomte, M; Mattmuller, R [Commissariat a l' Energie Atomique, Saclay (France).Centre d' Etudes Nucleaires

1959-07-01

A calibration method for a classical apparatus for differential thermal analysis is described in detail. This method achieves a relative precision of 5 per cent in the measurement of the internal energy release accompanying the annealing of irradiated graphites. Elastic constants of graphites are obtained from the frequencies of the longitudinal modes of vibration; procedures for excitation and detection of these vibrations at any temperature between -190 deg. C and +1500 deg. C are described. A procedure for obtaining easily measured deformations of graphites after relatively little irradiation with thermal neutrons is discussed. An application of this method to the study of the thermal annealing of elongation caused by displaced atoms is indicated. (author) [French] On decrit en detail une methode d'etalonnage pour un appareil classique d'analyse thermique differentielle. Cette methode permet de mesurer avec une precision relative de 5% la liberation d'energie interne qui accompagne le 'recuit' des graphites irradies. On deduit les constantes elastiques des graphites des frequences des vibrations longitudinales et on decrit les procedes pour exciter et detecter ces vibrations a toutes les temperatures comprises entre -190 deg. C et + 1500 deg. C. On discute un procede pour obtenir une des deformations de graphites facilement mesurables apres une irradiation relativement faible a l'aide de neutrons thermiques. Une application de cette methode a l'etude du 'recuit' thermique de l'elongation causee par les atomes deplaces est indiquee. (auteur)

A multiobserver study of the effects of including point-of-care patient photographs with portable radiography: a means to detect wrong-patient errors.

Science.gov (United States)

Tridandapani, Srini; Ramamurthy, Senthil; Provenzale, James; Obuchowski, Nancy A; Evanoff, Michael G; Bhatti, Pamela

2014-08-01

To evaluate whether the presence of facial photographs obtained at the point-of-care of portable radiography leads to increased detection of wrong-patient errors. In this institutional review board-approved study, 166 radiograph-photograph combinations were obtained from 30 patients. Consecutive radiographs from the same patients resulted in 83 unique pairs (ie, a new radiograph and prior, comparison radiograph) for interpretation. To simulate wrong-patient errors, mismatched pairs were generated by pairing radiographs from different patients chosen randomly from the sample. Ninety radiologists each interpreted a unique randomly chosen set of 10 radiographic pairs, containing up to 10% mismatches (ie, error pairs). Radiologists were randomly assigned to interpret radiographs with or without photographs. The number of mismatches was identified, and interpretation times were recorded. Ninety radiologists with 21 ± 10 (mean ± standard deviation) years of experience were recruited to participate in this observer study. With the introduction of photographs, the proportion of errors detected increased from 31% (9 of 29) to 77% (23 of 30; P = .006). The odds ratio for detection of error with photographs to detection without photographs was 7.3 (95% confidence interval: 2.29-23.18). Observer qualifications, training, or practice in cardiothoracic radiology did not influence sensitivity for error detection. There is no significant difference in interpretation time for studies without photographs and those with photographs (60 ± 22 vs. 61 ± 25 seconds; P = .77). In this observer study, facial photographs obtained simultaneously with portable chest radiographs increased the identification of any wrong-patient errors, without substantial increase in interpretation time. This technique offers a potential means to increase patient safety through correct patient identification. Copyright © 2014 AUR. Published by Elsevier Inc. All rights reserved.

Righting wrongs and reforming rights.

Science.gov (United States)

Ivey, Laurie C

2014-03-01

Discusses issues faced by LGBT people, such as a lack of equal civil rights and the need for extra legal and financial protection for families because partners cannot be married. The author notes that, in our society, it is no longer acceptable to be racist, but it is still okay to be homophobic. The many campaigns against gay marriage and efforts in the legislature to prevent change toward equal civil rights and protections are prime examples. In our current political climate, two things are very clear: (a) homophobia is freely tolerated and (b) the times are changing as we inch closer to equal rights every day. We are "righting wrongs and reforming rights."

What's wrong with anomalous chiral gauge theory?

International Nuclear Information System (INIS)

Kieu, T.D.

1994-05-01

It is argued on general ground and demonstrated in the particular example of the Chiral Schwinger Model that there is nothing wrong with apparently anomalous chiral gauge theory. If quantised correctly, there should be no gauge anomaly and chiral gauge theory should be renormalisable and unitary, even in higher dimensions and with non-Abelian gauge groups. Furthermore, it is claimed that mass terms for gauge bosons and chiral fermions can be generated without spoiling the gauge invariance. 19 refs

Application of the chemical properties of ruthenium to decontamination processes; L'application des proprietes chimiques du ruthenium a des procedes de decontamination

Energy Technology Data Exchange (ETDEWEB)

Fontaine, A; Berger, D [Commissariat a l' Energie Atomique, Centre de Production de Plutonium, Marcoule (France). Centre d' Etudes Nucleaires

1965-07-01

The chemical properties of ruthenium in the form of an aqueous solution of the nitrate and of organic tributylphosphate solution are reviewed. From this data, some known examples are given: they demonstrate the processes of separation or of elimination of ruthenium from radioactive waste. (authors) [French] Les proprietes chimiques du ruthenium en solutions aqueuses nitriques et en solutions organiques de tributylphosphate, sont passees en revue. A partir de ces donnees, quelques exemples connus sont cites: ils exposent des procedes de separation ou d'elimination du ruthenium de dechets radioactifs. (auteurs)

LHCb: Wrong-Sign to Right-Sign Yield in Flavor Tagged $D^0 \\to K\\pi$ Data at LHCb

CERN Multimedia

Bessner, M

2011-01-01

Initial results on wrong-sign $D^0 \\rightarrow K^+ \\pi^-$ decays based on the 2010 dataset are presented: the selection criteria, the yield, the time-integrated ratio of wrong-sign to right-sign ($D^0 \\rightarrow K^- \\pi^+$) decays, and a decay time acceptance corrected ratio. The corrected ratio is measured to be $R_{acc \\, cor} = (0.409 \\pm 0.031 (stat.) \\pm 0.039 (sys.)) \\%$. This analysis is the first step towards the measurement of the time-dependent wrong-sign/right-sign ratio from which $D^0$ mixing parameters may be extracted.

Desalting of sea water by a wall-less evaporation process; Dessalement de l'eau de mer par un procede d'evaporation sans paroi

Energy Technology Data Exchange (ETDEWEB)

Kassel, C.; Sachine, P.; Vuillemey, R. [Commissariat a l' Energie Atomique, Centre d' Etudes Nucleaires de Saclay, 91 - Gif-sur-Yvette (France)

1966-06-01

The need for fresh water supplies in many parts of the globe has given a great impetus to the study of the desalting of sea-water. Research into this problem has been very varied. Although it is possible in the more-or-less near future that methods based on freezing may be developed, only evaporation methods have industrial applications at the present time. Amongst the many techniques using this method, the most favorably placed installations from the technical and economic points of view are those based on multiple effects and wall-less heat transfer. We have defined the characteristics of a wall-less evaporation process using the various factors involved in this evaporation: energy source, corrosion, furring, heat transfer, maximum temperature, etc... The unit considered in this work has a daily output of 100,000 m{sup 3}, and makes use of the multi-stage technique with an organic heat-carrier. The maximum temperature of the first stage is 150 deg C and the evaporation factor is 0.4. After the description of the process and, the calculation of the equipment, an economic estimate is given of the cost-price : 1.49 F/m{sup 3}. It is likely that more detailed study of the process (technique, equipment and energy consumed) should make it possible to obtain a significant improvement in the process and to reduce the price to 1 F/m{sup 3}. (authors) [French] Le probleme de l 'approvisionnement en eau de nombreuses regions du globe a mis a 1'ordre du jour le dessalement de l'eau de mer. Des recherches sur cette question ont ete faites dans de multiples directions. Si dans un avenir plus ou moins proche les procedes par congelation peuvent se developper, actuellement seules les methodes d'evaporation ont des applications industrielles. Parmi les nombreuses techniques qui visent a mettre en oeuvre ce principe, les installations a multiples effets et transfert de chaleur sans paroi semblent les mieux placees du point de vue technique et economique. A

What's Wrong with Walden Two? | Tabensky | South African Journal ...

African Journals Online (AJOL)

... his Brave New World. In short, I argue, perhaps scandalously, that one of the central conditions for genuine agency is that our lives are and must continue to be, to a large extent, out of our personal control. The promise of too much personal control, not too little (as Kane thinks), is what is wrong with Skinner's social utopia.

Application of the chemical properties of ruthenium to decontamination processes; L'application des proprietes chimiques du ruthenium a des procedes de decontamination

Energy Technology Data Exchange (ETDEWEB)

Fontaine, A.; Berger, D. [Commissariat a l' Energie Atomique, Centre de Production de Plutonium, Marcoule (France). Centre d' Etudes Nucleaires

1965-07-01

The chemical properties of ruthenium in the form of an aqueous solution of the nitrate and of organic tributylphosphate solution are reviewed. From this data, some known examples are given: they demonstrate the processes of separation or of elimination of ruthenium from radioactive waste. (authors) [French] Les proprietes chimiques du ruthenium en solutions aqueuses nitriques et en solutions organiques de tributylphosphate, sont passees en revue. A partir de ces donnees, quelques exemples connus sont cites: ils exposent des procedes de separation ou d'elimination du ruthenium de dechets radioactifs. (auteurs)

Examining Wrong Eye Implant Adverse Events in the Veterans Health Administration With a Focus on Prevention: A Preliminary Report.

Science.gov (United States)

Neily, Julia; Chomsky, Amy; Orcutt, James; Paull, Douglas E; Mills, Peter D; Gilbert, Christina; Hemphill, Robin R; Gunnar, William

2018-03-01

The study goals were to examine wrong intraocular lens (IOL) implant adverse events in the Veterans Health Administration (VHA), identify root causes and contributing factors, and describe system changes that have been implemented to address this challenge. This study represents collaboration between the VHA's National Center for Patient Safety (NCPS) and the National Surgery Office (NSO). This report includes 45 wrong IOL implant surgery adverse events reported to established VHA NCPS and NSO databases between July 1, 2006, and June 31, 2014. There are approximately 50,000 eye implant procedures performed each year in the VHA. Wrong IOL implant surgery adverse events are reported by VHA facilities to the NCPS and the NSO. Two authors (A.C. and J.N.) coded the reports for event type (wrong lens or expired lens) and identified the primary contributing factor (coefficient κ = 0.837). A descriptive analysis was conducted, which included the reported yearly event rate. The main outcome measure was the reported wrong IOL implant surgery adverse events. There were 45 reported wrong IOL implant surgery adverse events. Between 2011 and June 30, 2014, there was a significant downward trend (P = 0.02, R = 99.7%) at a pace of -0.08 (per 10,000 cases) every year. The most frequently coded primary contributing factor was incomplete preprocedure time-out (n = 12) followed by failure to perform double check of preprocedural calculations based upon original data and implant read-back at the time the surgical eye implant was performed (n = 10). Preventing wrong IOL implant adverse events requires diligence beyond performance of the preprocedural time-out. In 2013, the VHA has modified policy to ensure double check of preprocedural calculations and implant read-back with positive impact. Continued analysis of contributing human factors and improved surgical team communication are warranted.

Ethical Issues in Family Practice: My Culture – Right or Wrong?

African Journals Online (AJOL)

Health professionals educated in and practicing Western medicine in multicultural ... P K Moser & T L Carson,(Eds.)New York: Oxford University Press: 63., if a practice is harmful – as it is with FGM ... bad, or right or wrong independently of.

When Rewards Go Wrong: A Tale of Five Motivational Misdirects

Science.gov (United States)

Steel, Piers; MacDonnell, Rhiannon

2012-01-01

At the heart of most performance management systems is a reward program. However, even when we are doing everything else right, rewards can go wrong. Here, we explore five ways that external incentives can damage performance, from destroying altruistic behavior to distracting people from the task. Fortunately, most of these downfalls are…

The horror of wrong-site surgery continues: report of two cases in a regional trauma centre in Nigeria.

Science.gov (United States)

Nwosu, Arinze

2015-01-01

Wrong- site surgeries are iatrogenic errors encountered in the course of surgical patient management. Despite the 'never do harm' pledge in the 'Hippocratic Oath' drafted in 5(th) century BC, man is after all human, with this limitation manifesting in the physician's art despite his best intention. Beyond the catastrophic consequences of wrong- site surgery on the patient and surgeon, and the opprobrium on the art of medicine, the incidents have come to be regarded as a quality-of-care indicator. Orthopaedic surgery is a specialty with a preponderance of this phenomenon and the attendant medico-legal issues relating to malpractice claims. Consequently the specialty had pioneered institutional initiatives at preventing these 'friendly-fires'. Awareness and implementation of these initiatives however remain low in many parts of the world, hampered by a culture of denial and shame. This report presents two cases of wrong-site surgery following trauma from road-traffic accident. The first case was a closed reduction of the 'wrong' dislocated hip in the trauma/emergency unit under the care of senior residents, while the second case was attempted wrong-site surgery on the right leg in a patient with fracture of the left tibia, in conjunction with bilateral femoral fracture and right radio-ulnar fracture; by an experienced Chief Consultant Orthopaedic Surgeon operating elective list. Both are orthopaedic cases, each with some trauma to both lower extremeties. Neither of the cases was formally mentioned anywhere in clinical discourse in the hospital, much less a formal report or audit. There was no formal, institutionalized process to prevent wrong-site surgery in the health institution and this could have been largely responsible for these incidents. An open, mandatory process of reporting such incidents for relevant audit and awareness is necessary, as a mechanism for prevention rather than blame or punishment.

The causal cognition of wrong doing: incest, intentionality and morality

Directory of Open Access Journals (Sweden)

Rita eAstuti

2015-02-01

Full Text Available The paper concerns the role of intentionality in reasoning about wrong doing. Anthropologists have claimed that, in certain non-western societies, people ignore whether an act of wrong doing is committed intentionally or accidentally. To examine this proposition, we look at the case of Madagascar. We start by analyzing how Malagasy people respond to incest, and we find that in this case they do not seem to take intentionality into account: catastrophic consequences follow even if those who commit incest are not aware that they are related as kin; punishment befalls on innocent people; and the whole community is responsible for repairing the damage. However, by looking at how people reason about other types of wrong doing, we show that the role of intentionality is well understood, and that in fact this is so even in the case of incest. We therefore argue that, when people contemplate incest and its consequences, they simultaneously consider two quite different issues: the issue of intentionality and blame, and the much more troubling and dumbfounding issue of what society would be like if incest were to be permitted. This entails such a fundamental attack on kinship and on the very basis of society thatissues of intentionality and blame become irrelevant. Using the insights we derive from this Malagasy case study, we re-examine the results of Haidt’s psychological experiment on moral dumbfoundedness, which uses a story about incest between siblings as one of its test scenarios. We suggest that the dumbfoundedness that was documented among North American students may be explained by the same kind of complexity that we found in Madagascar. In light of this, we discuss the methodological limitations of experimental protocols, which are unable to grasp multiple levels of response. We also note the limitations of anthropological methods and the benefits of closer cross-disciplinary collaboration.

Letters to the Editor: Tattooing gone wrong | Hampton | South African ...

African Journals Online (AJOL)

South African Journal of Surgery. Journal Home · ABOUT THIS JOURNAL · Advanced Search · Current Issue · Archives · Journal Home > Vol 55, No 1 (2017) >. Log in or Register to get access to full text downloads. Username, Password, Remember me, or Register. Letters to the Editor: Tattooing gone wrong. M I Hampton ...

Psychiatric patients' views on why their involuntary hospitalisation was right or wrong: a qualitative study.

Science.gov (United States)

Katsakou, Christina; Rose, Diana; Amos, Tim; Bowers, Len; McCabe, Rosemarie; Oliver, Danielle; Wykes, Til; Priebe, Stefan

2012-07-01

To explore involuntary patients' retrospective views on why their hospitalisation was right or wrong. Involuntary patients were recruited from 22 hospitals in England and interviewed in-depth. The study drew on grounded theory and thematic analysis. Most of the patients felt mentally unwell before admission and out of control during their treatment. Despite these common experiences, three groups of patients with distinct views on their involuntary hospitalisation were identified: those who believed that it was right, those who thought it was wrong and those with ambivalent views. Those with retrospectively positive views believed that hospitalisation ensured that they received treatment, averted further harm and offered them the opportunity to recover in a safe place. They felt that coercion was necessary, as they could not recognise that they needed help when acutely unwell. Those who believed that involuntary admission was wrong thought that their problems could have been managed through less coercive interventions, and experienced hospitalisation as an unjust infringement of their autonomy, posing a permanent threat to their independence. Patients with ambivalent views believed that they needed acute treatment and that hospitalisation averted further harm. Nonetheless, they thought that their problems might have been managed through less coercive community interventions or a shorter voluntary hospitalisation. The study illustrates why some patients view their involuntary hospitalisation positively, whereas others believe it was wrong. This knowledge could inform the development of interventions to improve patients' views and treatment experiences.

Improving patient safety through a clinical audit spiral: prevention of wrong tooth extraction in orthodontics.

Science.gov (United States)

Anwar, H; Waring, D

2017-07-07

Introduction With an increasing demand to improve patient safety within the NHS, it is important to ensure that measures are undertaken to continually improve patient care. Wrong site surgery has been defined as a 'never event'. This article highlights the importance of preventing wrong tooth extraction within orthodontics through an audit spiral over five years investigating the accuracy and clarity of orthodontic extraction letters at the University Dental Hospital of Manchester.Aims To examine compliance with the standards for accuracy and clarity of extraction letters and the incidence of wrong tooth extractions, and to increase awareness of the errors that can occur with extraction letters and of the current guidelines.Method A retrospective audit was conducted examining extraction letters sent to clinicians outside the department.Results It can be seen there has been no occurrence of a wrong site tooth extraction. The initial audit highlighted issues in conformity, with it falling below expected standards. Cycle two generally demonstrated a further reduction in compliance. Cycle three appeared to result in an increase in levels of compliance. Cycles 4 and 5 have demonstrated gradual improvements. However, it is noteworthy that in all cycles the audit standards were still not achieved, with the exception of no incidences of the incorrect tooth being extracted.Conclusion This audit spiral demonstrates the importance of long term re-audit to aim to achieve excellence in clinical care. There has been a gradual increase in standards through each audit.

2008 State-of-the-Art : High Level Radioactive Waste Disposal Facilities and Project Review of Proceding Countries

Energy Technology Data Exchange (ETDEWEB)

Choi, Heui Joo; Choi, Jong Won; Lee, Jong Youl; Jung, Jong Tae; Kim, Sung Ki; Lee, Min Soo; Cho, Dong Keun; Kook, Dong Hak

2008-11-15

High level radioactive waste disposal system project for advanced nuclear fuel cycle produced this report which are dealing with the repository status of proceding countries as of 2008. This report has brief review on disposal facilities which are operating and will be operating and on future plan of those nations. The other report 'Development of the Geological Disposal System for High Level Waste' which was produced like this report time and this report would help the readers grasp the current repository status. Because our country is a latecomer in the HLW disposal world, it is strongly recommended to catch up with advanced disposal system and concepts of developed nations and this report is expected to make it possible. There are several nations which were the main survey target; Finland, USA, Sweden, Germany, France, Switzerland, and Japan. Recent information was applied to this report and our project team will produce annual state-of-the-art report with continuous updates.

Time integrated ratio of wrong-sign to right-sign $D^0 \\rightarrow K\\pi$ decays in 2010 data at LHCb

CERN Document Server

The LHCb Collaboration

2011-01-01

First results of the measurement on wrong-sign $D^0 \\rightarrow K^{+} \\pi^{-}$ decays based on the 2010 dataset taken with the LHCb detector are presented. The ratio of wrong-sign to right-sign ($D^0 \\rightarrow K^{-} \\pi^{+}$) $D^0$ decays corrected for the decay time acceptance is determined to be $R_{{\\rm corr}}=(0.409 \\pm 0.031 ({\\rm stat.}) \\pm 0.039 ({\\rm sys.})) \\% $. This analysis is the first step towards a measurement of the time-dependent wrong-sign to right-sign ratio from which the $D^0$ mixing parameters can be extracted.

PROPAGANDA: HOW A GOOD WORD WENT WRONG

Directory of Open Access Journals (Sweden)

CRISTINA LUCIA ŞUTIU

2012-11-01

Full Text Available What is propaganda and what is wrong with it? This may be the main question when studying this complex phenomenon. In this article we shall try to give an answer to this question and to find the most appropriate definition for this disputed concept. Nowadays, propaganda has a negative connotation and usually it is used to discredit somebody’s speech or actions, by implying that he is both illogical and unethical. But propaganda wasn’t seen always like that! In order to give an objective definition of this concept, it is very important for us to understand first what exactly happened with this word throughout history.

Landing on the Wrong Note: The Price We Paid for "Brown." 2004 DeWitt Wallace-"Reader's Digest" Distinguished Lecture

Science.gov (United States)

Ladson-Billings, Gloria

2004-01-01

The first part of the title of this lecture is taken from Ajay Heble's (2000) book "Landing on the Wrong Note: Jazz, Dissonance, and Critical Practice." The author chose this musical image to convey the problem of good intentions gone awry. No musician plans to play the wrong note. The plaintiffs, litigators, Supreme Court Justices, and civil…

Court decisions in wrongful birth cases as possible discrimination against the child

Directory of Open Access Journals (Sweden)

Petr Sustek

2017-04-01

Full Text Available Abstract: The term wrongful birth denotes a claim brought by the parents of an unwanted child who was conceived or born due to medical negligence. The claims are often dismissed as contradictory to good morals or public order. However, there remains a neglected question whether the court decision to award or dismiss damages could constitute discrimination against the child concerned. While the child is not a party to the litigation, it is nevertheless unacceptable for the court not to take into account the effects of its decision on the child. In the case of award of damages, the court publicly affirms the legitimacy of the parentsꞌ need for compensation, that is the fact that the childꞌs birth represents recoverable harm to them. The court decision therefore means a different treatment in respect to other children whose benefits for the family are generally recognized and praised by the society. That might have serious psychological consequences for the child, depriving her or him of the full enjoyment of the right to dignity. This fact constitutes discrimination on the grounds of birth, which can be justified only by very weighty reasons. Such reasons may be arguably given in the case of a child incapable of understanding the meaning of wrongful birth litigation, whose special needs are extremely burdensome on the family. On the other hand, the dismissal of the claim cannot represent a negative discrimination against the child. Keywords: Discrimination. Wrongful birth. International human rights law. Human rights of the child. Convention on the Rights of the Child.

What I got wrong about shelterin.

Science.gov (United States)

de Lange, Titia

2018-05-24

The ASBMB 2018 Bert and Natalie Vallee award in Biomedical Sciences honors our work on shelterin, a protein complex that helps cells distinguish the chromosome ends from sites of DNA damage. Shelterin protects telomeres from all aspects of the DNA damage response, including ATM and ATR serine/threonine kinase signaling and several forms of double-strand break repair. Today, this six-subunit protein complex could easily be identified in one single proteomics step. But it took us more than 15 years to piece the entire shelterin complex together, one protein at a time. Although we did a lot of things right, here I tell the story of shelterin's discovery with an emphasis on the things that I got wrong along the way. Published under license by The American Society for Biochemistry and Molecular Biology, Inc.

Wrong-Site Surgery, Retained Surgical Items, and Surgical Fires : A Systematic Review of Surgical Never Events.

Science.gov (United States)

Hempel, Susanne; Maggard-Gibbons, Melinda; Nguyen, David K; Dawes, Aaron J; Miake-Lye, Isomi; Beroes, Jessica M; Booth, Marika J; Miles, Jeremy N V; Shanman, Roberta; Shekelle, Paul G

2015-08-01

Serious, preventable surgical events, termed never events, continue to occur despite considerable patient safety efforts. To examine the incidence and root causes of and interventions to prevent wrong-site surgery, retained surgical items, and surgical fires in the era after the implementation of the Universal Protocol in 2004. We searched 9 electronic databases for entries from 2004 through June 30, 2014, screened references, and consulted experts. Two independent reviewers identified relevant publications in June 2014. One reviewer used a standardized form to extract data and a second reviewer checked the data. Strength of evidence was established by the review team. Data extraction was completed in January 2015. Incidence of wrong-site surgery, retained surgical items, and surgical fires. We found 138 empirical studies that met our inclusion criteria. Incidence estimates for wrong-site surgery in US settings varied by data source and procedure (median estimate, 0.09 events per 10,000 surgical procedures). The median estimate for retained surgical items was 1.32 events per 10,000 procedures, but estimates varied by item and procedure. The per-procedure surgical fire incidence is unknown. A frequently reported root cause was inadequate communication. Methodologic challenges associated with investigating changes in rare events limit the conclusions of 78 intervention evaluations. Limited evidence supported the Universal Protocol (5 studies), education (4 studies), and team training (4 studies) interventions to prevent wrong-site surgery. Limited evidence exists to prevent retained surgical items by using data-matrix-coded sponge-counting systems (5 pertinent studies). Evidence for preventing surgical fires was insufficient, and intervention effects were not estimable. Current estimates for wrong-site surgery and retained surgical items are 1 event per 100,000 and 1 event per 10,000 procedures, respectively, but the precision is uncertain, and the per

Conceptual design of a connected vehicle wrong-way driving detection and management system.

Science.gov (United States)

2016-04-01

This report describes the tasks completed to develop a concept of operations, functional requirements, and : high-level system design for a Connected Vehicle (CV) Wrong-Way Driving (WWD) Detection and Management : System. This system was designed to ...

Protein secondary structure assignment revisited: a detailed analysis of different assignment methods

Directory of Open Access Journals (Sweden)

de Brevern Alexandre G

2005-09-01

Full Text Available Abstract Background A number of methods are now available to perform automatic assignment of periodic secondary structures from atomic coordinates, based on different characteristics of the secondary structures. In general these methods exhibit a broad consensus as to the location of most helix and strand core segments in protein structures. However the termini of the segments are often ill-defined and it is difficult to decide unambiguously which residues at the edge of the segments have to be included. In addition, there is a "twilight zone" where secondary structure segments depart significantly from the idealized models of Pauling and Corey. For these segments, one has to decide whether the observed structural variations are merely distorsions or whether they constitute a break in the secondary structure. Methods To address these problems, we have developed a method for secondary structure assignment, called KAKSI. Assignments made by KAKSI are compared with assignments given by DSSP, STRIDE, XTLSSTR, PSEA and SECSTR, as well as secondary structures found in PDB files, on 4 datasets (X-ray structures with different resolution range, NMR structures. Results A detailed comparison of KAKSI assignments with those of STRIDE and PSEA reveals that KAKSI assigns slightly longer helices and strands than STRIDE in case of one-to-one correspondence between the segments. However, KAKSI tends also to favor the assignment of several short helices when STRIDE and PSEA assign longer, kinked, helices. Helices assigned by KAKSI have geometrical characteristics close to those described in the PDB. They are more linear than helices assigned by other methods. The same tendency to split long segments is observed for strands, although less systematically. We present a number of cases of secondary structure assignments that illustrate this behavior. Conclusion Our method provides valuable assignments which favor the regularity of secondary structure segments.

Fast measure proceeding of weak currents; Un procede de mesure rapide des courants faibles

Energy Technology Data Exchange (ETDEWEB)

Taieb, J [Commissariat a l' Energie Atomique, Siege (France). Centre d' Etudes Nucleaires

1953-07-01

The process of fast measure of the weak currents that we are going to describe briefly apply worthy of the provided currents by the sources to elevated value internal resistance, as it is the case for the ionization chamber, the photocells, mass spectroscopic tubes. The problem to measure weak currents is essentially a problem of amplifier and of input circuit. We intended to achieve a whole amplifier and input circuit with advanced performances, meaning that for a measured celerity we wanted to have an signal/noise ratio the most important as in the classic systems and for a same report signal/noise a more quickly done measure. (M.B.) [French] Le procede de mesure rapide des courants faibles que nous allons brievement decrire s'applique a la mesure des courants fournis par les sources a resistance interne de valeur elevee, comme c'est le cas pour les chambres d'ionisation, les photocellules, les tubes de spectrographe de masse. Le probleme de mesure de courants faibles est essentiellement un probleme d'amplificateur et de circuit d'entree. Nous nous sommes proposes de realiser un ensemble amplificateur et circuit d'entree a performances poussees, c'est a dire que pour une meme rapidite de mesure nous desirions avoir un rapport signal/bruit plus important que dans les systemes classiques et pour un meme rapport signal/bruit une mesure effectuee plus rapidement. (M.B.)

p p →A →Z h and the wrong-sign limit of the two-Higgs-doublet model

Science.gov (United States)

Ferreira, Pedro M.; Liebler, Stefan; Wittbrodt, Jonas

2018-03-01

We point out the importance of the decay channels A →Z h and H →V V in the wrong-sign limit of the two-Higgs-doublet model (2HDM) of type II. They can be the dominant decay modes at moderate values of tan β , even if the (pseudo)scalar mass is above the threshold where the decay into a pair of top quarks is kinematically open. Accordingly, large cross sections p p →A →Z h and p p →H →V V are obtained and currently probed by the LHC experiments, yielding conclusive statements about the remaining parameter space of the wrong-sign limit. In addition, mild excesses—as recently found in the ATLAS analysis b b ¯→A →Z h —could be explained. The wrong-sign limit makes other important testable predictions for the light Higgs boson couplings.

Wrong directions of the energetic policy; Descaminhos da politica energetica

Energy Technology Data Exchange (ETDEWEB)

Carvalho, Joaquim Francisco

1997-12-31

The energetic planning should take an important role in the formulation of the economic and social development policy of any country. This work presents the opinion of the author in relation to this issue in what concerns the Brazilian experience. Several actions considered wrong by the author, which were taken by the government in what concerns energetic policy are presented and their expected consequences in the near future are discussed 6 refs., 1 tab.

A study of wrong-sign single muon production in νμ-nucleon interaction

International Nuclear Information System (INIS)

Mishra, S.R.; Auchincloss, P.S.; Blair, R.; Haber, C.; Ruiz, M.; Oltman, E.; Sciulli, F.J.; Shaevitz, M.H.; Smith, W.H.; Merritt, F.S.; Oreglia, M.; Reutens, P.; Coleman, R.; Fisk, H.E.; Lamm, M.J.; Levinthal, D.; Yovanovitch, D.D.; Marsh, W.; Rapidis, P.A.; White, H.B.; Bodek, A.; Borcherding, F.; Giokaris, N.; Lang, K.; Stockdale, I.E.

1989-01-01

We report on a search for ν μ -induced events where the single emerging muon carries lepton number opposite that of the incident neutrino. The rate and kinematic quantities of the candidate events are compared with known backgrounds from anti ν μ -induced charged current interactions and ν-induced interactions that produce dileptons. We derive an upper limit on the rate of wrong-sign single muon production relative to the rate of ν μ charged current interactions to be 1.6x10 -4 for y -4 for y>0.5 (90% CL). These upper limits enable us to constrain exotic sources of wrong-sign muons such as the charm component of the nucleon sea, flavor changing neutral currents and lepton number violating processes. Finally, the rate and kinematic properties of these events are compared with those of the neutrino-induced opposite-sign dimuon events. (orig.)

The Reputational Consequences of Failed Replications and Wrongness Admission among Scientists.

Directory of Open Access Journals (Sweden)

Adam K Fetterman

Full Text Available Scientists are dedicating more attention to replication efforts. While the scientific utility of replications is unquestionable, the impact of failed replication efforts and the discussions surrounding them deserve more attention. Specifically, the debates about failed replications on social media have led to worry, in some scientists, regarding reputation. In order to gain data-informed insights into these issues, we collected data from 281 published scientists. We assessed whether scientists overestimate the negative reputational effects of a failed replication in a scenario-based study. Second, we assessed the reputational consequences of admitting wrongness (versus not as an original scientist of an effect that has failed to replicate. Our data suggests that scientists overestimate the negative reputational impact of a hypothetical failed replication effort. We also show that admitting wrongness about a non-replicated finding is less harmful to one's reputation than not admitting. Finally, we discovered a hint of evidence that feelings about the replication movement can be affected by whether replication efforts are aimed one's own work versus the work of another. Given these findings, we then present potential ways forward in these discussions.

The Reputational Consequences of Failed Replications and Wrongness Admission among Scientists.

Science.gov (United States)

Fetterman, Adam K; Sassenberg, Kai

2015-01-01

Scientists are dedicating more attention to replication efforts. While the scientific utility of replications is unquestionable, the impact of failed replication efforts and the discussions surrounding them deserve more attention. Specifically, the debates about failed replications on social media have led to worry, in some scientists, regarding reputation. In order to gain data-informed insights into these issues, we collected data from 281 published scientists. We assessed whether scientists overestimate the negative reputational effects of a failed replication in a scenario-based study. Second, we assessed the reputational consequences of admitting wrongness (versus not) as an original scientist of an effect that has failed to replicate. Our data suggests that scientists overestimate the negative reputational impact of a hypothetical failed replication effort. We also show that admitting wrongness about a non-replicated finding is less harmful to one's reputation than not admitting. Finally, we discovered a hint of evidence that feelings about the replication movement can be affected by whether replication efforts are aimed one's own work versus the work of another. Given these findings, we then present potential ways forward in these discussions.

The reprocessing of irradiated fuels improvement and extension of the solvent extraction process; Le traitement des combustibles irradies amelioration et extension du procede utilisant les solvants

Energy Technology Data Exchange (ETDEWEB)

Faugeras, P; Chesne, A [Commissariat a l' Energie Atomique, Fontenay-aux-Roses (France). Centre d' Etudes Nucleaires

1964-07-01

Improvements made in the conventional tri-butylphosphate process are described, in particular. the concentration and the purification of plutonium by one extraction cycle using tri-butyl-phosphate with reflux; and the use of an apparatus working continuously for precipitating plutonium oxalate, for calcining the oxalate, and for fluorinating the oxide. The modifications proposed for the treatment of irradiated uranium - molybdenum alloys are described, in particular, the dissolution of the fuel, and the concentration of the fission product solutions. The solvent extraction treatment is used also for the plutonium fuels utilized for the fast breeder reactor (Rapsodie) An outline of the process is presented and discussed, as well as the first experimental results and the plans for a pilot plant having a capacity of 1 kg/day. The possible use of tn-lauryl-amine in the plutonium purification cycle is now under consideration for the processing plant at La Hague. The flowsheet for this process and its performance are presented. The possibility of vitrification is considered for the final treatment of the concentrated radioactive wastes from the Marcoule (irradiated uranium) and La Hague (irradiated uranium-molybdenum) Centers. Three possible processes are described and discussed, as well as the results obtained from the operation of the corresponding experimental units using tracers. (authors) [French] On decrit les ameliorations apportees au procede classique utilisant le phosphate tributylique, et notamment la concentration et la purification du plutonium par un cycle d'extraction au tributylphosphate avec reflux, l'utilisation d'un appareillage continu de precipitation d'oxalate de plutonium, de calcination de l'oxalate, et de fluoration de l'oxyde. On presente les modifications envisagees pour le traitement des alliages uranium-molybdene irradies, principalement en ce qui concerne la dissolution du combustible et la concentration des solutions de produits de fission

Nuclear power is neither right nor wrong: the case for a tertium datur in the ethics of technology.

Science.gov (United States)

Hillerbrand, Rafaela; Peterson, Martin

2014-06-01

The debate over the civilian use of nuclear power is highly polarised. We argue that a reasonable response to this deep disagreement is to maintain that advocates of both camps should modify their positions. According to the analysis we propose, nuclear power is neither entirely right nor entirely wrong, but rather right and wrong to some degree. We are aware that this non-binary analysis of nuclear power is controversial from a theoretical point of view. Utilitarians, Kantians, and other moral theorists make sharp, binary distinctions between right and wrong acts. However, an important argument speaking in favour of our non-binary analysis is that it better reflects our considered intuitions about the ethical trade-offs we face in discussions of nuclear power. The aim of this article is to make this argument sharp by explaining how it can be rendered compatible with, and supported by, the Capability Approach, which is quickly becoming one of the most influential frameworks for thinking about human development.

Grouping puts figure-ground assignment in context by constraining propagation of edge assignment.

Science.gov (United States)

Brooks, Joseph L; Brook, Joseph L; Driver, Jon

2010-05-01

Figure-ground organization involves the assignment of edges to a figural shape on one or the other side of each dividing edge. Established visual cues for edge assignment primarily concern relatively local rather than contextual factors. In the present article, we show that an assignment for a locally unbiased edge can be affected by an assignment of a remote contextual edge that has its own locally biased assignment. We find that such propagation of edge assignment from the biased remote context occurs only when the biased and unbiased edges are grouped. This new principle, whereby grouping constrains the propagation of figural edge assignment, emerges from both subjective reports and an objective short-term edge-matching task. It generalizes from moving displays involving grouping by common fate and collinearity, to static displays with grouping by similarity of edge-contrast polarity, or apparent occlusion. Our results identify a new contextual influence on edge assignment. They also identify a new mechanistic relation between grouping and figure-ground processes, whereby grouping between remote elements can constrain the propagation of edge assignment between those elements. Supplemental materials for this article may be downloaded from http://app.psychonomic-journals.org/content/supplemental.

FLEET ASSIGNMENT MODELLING

Directory of Open Access Journals (Sweden)

2016-01-01

Full Text Available The article is devoted to the airline scheduling process and methods of its modeling. This article describes the main stages of airline scheduling process (scheduling, fleet assignment, revenue management, operations, their features and interactions. The main part of scheduling process is fleet assignment. The optimal solution of the fleet assignment problem enables airlines to increase their incomes up to 3 % due to quality improving of connections and execution of the planned number of flights operated by less number of aircraft than usual or planned earlier. Fleet assignment of scheduling process is examined and Conventional Leg-Based Fleet Assignment Model is analyzed. Finally strong and weak aspects of the model (SWOT are released and applied. The article gives a critical analysis of FAM model, with the purpose of identi- fying possible options and constraints of its use (for example, in cases of short-term and long-term planning, changing the schedule or replacing the aircraft, as well as possible ways to improve the model.

Germalna, a new genus for the New Caledonian cicada previously assigned to the genus Melampsalta Kolenati, plus a complement to the description of the genus Rouxalna Boulard, with the description of two new species (Insecta: Hemiptera, Cicadoidea, Cicadidae).

Science.gov (United States)

Delorme, Quentin

2018-01-31

Species previously assigned to Melampsalta Kolenati, in New Caledonia are reviewed. Morphological studies indicate that New Caledonian cicadas currently placed in this genus have been wrongly assigned and should be placed in a new genus. The genus Germalna gen. nov., is therefore erected to accommodate Germalna germaini comb. nov. The genus Germalna gen. nov. was first documented by Michel Boulard, but remained a nomen nudum until now. A redescription of the genus Rouxalna Boulard is provided and the following new species are described: Rouxalna villosa sp. nov., and Rouxalna scabens sp. nov. Male calling songs of Rouxalna rouxi Boulard and Rouxalna scabens sp. nov. are analysed and described from field recordings. A key to the species of Rouxalna is also provided.

Delegation and beyond: what happens when things go wrong?

Science.gov (United States)

Solon, Mark

2013-01-01

Both midwives and maternity support workers can be confused about who is liable if a task is delegated and something goes wrong. With proper understanding of roles and a knowledge of which tasks can and can't be delegated, however, the midwife should be protected, particularly as in practice the NHS body will have vicarious liability in the event of any claim. Clinical negligence training identifies the risks and responsibilities involved--and, leaving aside issues of delegation, training should also instil common sense safeguards against incurring criminal liability, which is independent from any professional or civil sanction.

The Impact of Adding Online Homework Assignments to an Introduction to Physical Geology Class

Science.gov (United States)

Brevik, Eric C.

2017-04-01

As instructors we are constantly looking for ways to improve student performance in the classroom. In an attempt to improve student performance in my GEOL 105 - Introduction to Physical Geology class, I added online homework assignments from the Pearson Mastering Geology program beginning in the Fall semester of 2014. There were several anticipated advantages to the online homework approach. If a student is struggling with a question they can get hints that don't tell them the answer, but are designed to stimulate their thinking and lead them towards the correct answer. The students also know immediately after submitting their answers which questions they got right and which were wrong, and they can go back to the wrong answers and try to determine the correct answer so they know what it is. This gives them much more rapid feedback than traditional paper homework, all of which makes this a more student-centered approach to learning. It is also my hope that the students find the online homework more interesting and interactive than paper-based homework, which I hope in turn will stimulate the students to be more likely to do the homework and take it seriously while also having some fun while doing it. As of the end of Fall semester 2016, I had been using the online homework assignments in my classes for three years. Therefore, I analyzed student performance in the three years prior to adopting the online homework and compared it to performance over the three years since adopting online homework. In the three years prior to adopting the online homework, the average grade in my classes was 73.8%; afterwards the average grade was 81.3%, for an improvement of 7.5% on average. Most of that improvement was in average test scores, which increased by 6.3% (67.4% prior to 73.6% after). The online homework did not improve the performance of the top students, but it did improve the performance of the other students. Prior to adopting the online homework, grade distribution in

Moving Past "Right" or "Wrong" toward a Continuum of Young Children's Semantic Knowledge

Science.gov (United States)

Christ, Tanya

2011-01-01

Vocabulary development is a critical goal for early childhood education. However, it is difficult for researchers and teachers to determine whether this goal is being met, given the limitations of current assessment tools. These tools tend to view word knowledge dichotomously--as right or wrong. A clear sense of children's depth of semantic…

When patients are harmed, but are not wronged: ethics, law, and history.

Science.gov (United States)

Klaas, Paul B; Berge, Keith H; Klaas, Kelsey M; Klaas, James P; Larson, Annalise Noelle

2014-09-01

Iatrogenic injury-injury caused unintentionally by medical treatment-breaks the oldest and most famous rule of medical ethics: primum non nocere, or above all, do no harm. Medical malpractice law, however, focuses on whether an injury was caused by negligence, not on whether an injury was iatrogenic. Iatrogenic injury inflicted without negligence is a common pattern in medical malpractice lawsuits; it is likely the pattern of Jacobs v Cross (Minnesota, 1872), in which Dr W. W. Mayo testified as an expert witness. As a matter of law, the doctor defendants should win all those lawsuits, for iatrogenic injury inflicted without negligence is not a legal wrong in the United States and has not been considered a legal wrong for hundreds of years. However, the medical ethics applicable to doctors' duties to report incompetence in colleagues, including those who inflict excessive iatrogenic injury, have developed dramatically over time. In 1872, the ethical codes in the United States exhorted doctors not to criticize another doctor, even if incompetent. Today, doctors in the United States are ethically required to report an incompetent colleague. Copyright © 2014 Mayo Foundation for Medical Education and Research. Published by Elsevier Inc. All rights reserved.

Development and Testing of a Prototype Connected Vehicle Wrong-Way Driving Detection and Management System

Science.gov (United States)

2018-02-01

The primary objective of Phase II was to develop a prototype connected vehicle wrong-way driving detection and management system at the Texas A&M University Respect, Excellence, Leadership, Loyalty, Integrity, Selfless Service (RELLIS) campus. The pu...

UOP LDR 300 All Assignments New

OpenAIRE

ADMIN

2018-01-01

UOP LDR 300 All Assignments New Check this A+ tutorial guideline at http://www.ldr300assignment.com/ldr-300-uop/ldr-300-all-assignments-latest For more classes visit http://www.ldr300assignment.com LDR 300 Week 1 Assignment Leadership Assessment (2 Papers) LDR 300 Week 2 Assignment Leadership Theories Matrix (2 Set) LDR 300 Week 2 Assignment Formulating Leadership Part I (2 Papers) LDR 300 Week 3 Assignment Interaction and Influence Amo...

Fair Package Assignment

Science.gov (United States)

Lahaie, Sébastien; Parkes, David C.

We consider the problem of fair allocation in the package assignment model, where a set of indivisible items, held by single seller, must be efficiently allocated to agents with quasi-linear utilities. A fair assignment is one that is efficient and envy-free. We consider a model where bidders have superadditive valuations, meaning that items are pure complements. Our central result is that core outcomes are fair and even coalition-fair over this domain, while fair distributions may not even exist for general valuations. Of relevance to auction design, we also establish that the core is equivalent to the set of anonymous-price competitive equilibria, and that superadditive valuations are a maximal domain that guarantees the existence of anonymous-price competitive equilibrium. Our results are analogs of core equivalence results for linear prices in the standard assignment model, and for nonlinear, non-anonymous prices in the package assignment model with general valuations.

Eyewitness Testimony, False Confession, and Human Performance Technology: An Examination of Wrongful Convictions

Science.gov (United States)

Johnson, Terry L.

2013-01-01

Wrongful criminal convictions have come to the attention of the public and the criminal justice community in recent decades as a result of DNA evidence that has proven innocence after conviction. Research has suggested that as many as 3% to 5% of people currently imprisoned did not, in fact, commit the crimes for which they were convicted. A…

Determination of the Wrong Sign Decay Rate D0 -> K+pi- and the Sensitivity to D0-D0bar Mixing

International Nuclear Information System (INIS)

Egede, Ulrik

2001-01-01

The D 0 meson can decay to the wrong sign K + π - state either through a doubly Cabibbo suppressed decay or via mixing to the (bar D) 0 state followed by the Cabibbo favoured decay (bar D) 0 → K + π - . We measure the rate of wrong sign decays relative to the Cabibbo favoured decay to (0.383 ± 0.044 ± 0.022)% and give our sensitivity to a mixing signal

Laue: right or wrong?

International Nuclear Information System (INIS)

Datta, Timir

2015-01-01

In 1912, Laue spots were discovered in x-ray scattering ‘photograms’ of crystals, which were amongst the most consequential experimental findings of the 20th century. Inter alia, spots established the x-ray waves and crystal lattice; plus, for the first time ever, revealed atoms as real physical objects. Laue, a protégé of Planck and a wave-optics expert, had theoretically predicted these spots, and promptly won the Physics Nobel Prize for 1914. The prize did not come easy: executing his experimentum cruces, over the judgments of Sommerfeld and Wien, required force of will and a certain amount of diplomacy. Besides, his explanation for missing spots and x-ray diffraction were proven wrong by Moseley, Darwin and the two Braggs. Traditionally, Laue’s three-dimensional diffraction model is reconciled with Bragg’s reflection formula by Ewald’s construction using reciprocal lattice space. Laue had overlooked that his fundamental equations violate Euclidean length invariance. This article shows that implementation of invariance consolidates Laue’s system of three (multi-parameter) equations into a single formula containing one integer, one angle and two distances; plus validating Bragg’s conjecture of reflection. This new derivation demonstrates that the mechanism of Laue spots is akin to the anti reflection coating the colour-plays in soap bubbles and oil slicks—reflection and interference not diffraction. Yet, Laue stimulated countless breakthroughs: Nobel Prizes and scientific innovations, with an enduring legacy of inspiration a century later. (invited comment)

Laue: right or wrong?

Science.gov (United States)

Datta, Timir

2015-03-01

In 1912, Laue spots were discovered in x-ray scattering ‘photograms’ of crystals, which were amongst the most consequential experimental findings of the 20th century. Inter alia, spots established the x-ray waves and crystal lattice; plus, for the first time ever, revealed atoms as real physical objects. Laue, a protégé of Planck and a wave-optics expert, had theoretically predicted these spots, and promptly won the Physics Nobel Prize for 1914. The prize did not come easy: executing his experimentum cruces, over the judgments of Sommerfeld and Wien, required force of will and a certain amount of diplomacy. Besides, his explanation for missing spots and x-ray diffraction were proven wrong by Moseley, Darwin and the two Braggs. Traditionally, Laue’s three-dimensional diffraction model is reconciled with Bragg’s reflection formula by Ewald’s construction using reciprocal lattice space. Laue had overlooked that his fundamental equations violate Euclidean length invariance. This article shows that implementation of invariance consolidates Laue’s system of three (multi-parameter) equations into a single formula containing one integer, one angle and two distances; plus validating Bragg’s conjecture of reflection. This new derivation demonstrates that the mechanism of Laue spots is akin to the anti reflection coating the colour-plays in soap bubbles and oil slicks—reflection and interference not diffraction. Yet, Laue stimulated countless breakthroughs: Nobel Prizes and scientific innovations, with an enduring legacy of inspiration a century later.

What went wrong in California's electricity market?

International Nuclear Information System (INIS)

Chikeung Woo

2001-01-01

The California electricity market reform promised to deliver reliable service at low and stable prices. Frequent capacity shortages and the ensuing rolling black-outs, price spikes, and large price volatility since Summer 2000 raise a simple but substantive question: what went wrong? The answer to this question will help countries contemplating electricity market reform not to commit similar mistakes. We find the answer by identifying the major factors that have turned the California dream into a nightmare. Such factors include poor market design, market power, sustained demand growth not matched by new capacity, rising marginal cost, and financial insolvency. Proposed remedies include an alternative market settlement process, long-term contract, fast licensing and siting process for new generation and transmission, conservation and energy-efficiency, distributed resources, rate options, and debt restructuring. The California experience suggests that a reversible regulatory reform is a safe alternative to an irreversible market reform. (Author)

Plagiarism-Proofing Assignments

Science.gov (United States)

Johnson, Doug

2004-01-01

Mr. Johnson has discovered that the higher the level of student engagement and creativity, the lower the probability of plagiarism. For teachers who would like to see such desirable results, he describes the characteristics of assignments that are most likely to produce them. Two scenarios of types of assignments that avoid plagiarism are…

31 CFR 100.18 - Counterfeit notes to be marked; “redemption” of notes wrongfully so marked.

Science.gov (United States)

2010-07-01

... moneys, and all officers of national banks, shall stamp or write in plain letters the word “counterfeit... money, which shall be presented at their places of business; and if such officers shall wrongfully stamp...

Analysis of the events on the operating of the wrong compartment of NPPs

International Nuclear Information System (INIS)

Zheng Lixin; Zhou Hong; Zhang Hao; Che Shuwei; Zhang Jiajun

2013-01-01

In this paper, an operational event that unit trip caused by the operating of the wrong compartment, due to the personnel error is introduced. Through in-depth research on this kind of events the causes of the events are found, some suggestions are put forward. It can provide a reference for preventing the similar events from recurring to other NPPs. (authors)

Modeling wrong-way crashes and fatalities on arterials and freeways

Directory of Open Access Journals (Sweden)

Raj V. Ponnaluri

2018-04-01

Full Text Available Wrong way driving (WWD research and mitigation measures have primarily focused on limited access facilities. This is most likely due to the higher incidence of fatal WWD crashes with dramatic consequences on freeways, media attention, and a call for innovative solutions to address the problem. While public agencies and published literature address WWD incidence on freeway systems, the crash analyses on non-limited access facilities, i.e., arterial corridors, remains untouched. This research extends previous works and attempts to provide many new perspectives on arterial WWD incidence. In particular, one work showed that while WWD fatalities are more likely to occur on freeways, the likelihood of these crashes is higher on arterials. Hence this work with univariate and multivariate analyses of WWD and non-WWD crashes, and fatal and non-fatal WWD incidents. Results show the impressive negative impacts of alcohol use, driver defect, nighttime and weekend incidence, poor street lighting, low traffic volumes, rural geography, and median and shoulder widths. The objective here is to highlight the need for paying greater attention to WWD crashes on arterial corridors as is done with fatal WWD incidents on freeway systems. It suffices to say that while engineering countermeasures should evolve from the traditional signing and pavement markings to connected vehicle technology applications, there is a clear and compelling need to focus on educational campaigns specifically targeting drunken driving, and enforcement initiatives with an objective to mitigate WWD in the most efficient manner possible. Keywords: Wrong-way driving, Modeling, Arterials and freeways, Logistic regression, Likelihood

Group navigation and the "many-wrongs principle" in models of animal movement.

Science.gov (United States)

Codling, E A; Pitchford, J W; Simpson, S D

2007-07-01

Traditional studies of animal navigation over both long and short distances have usually considered the orientation ability of the individual only, without reference to the implications of group membership. However, recent work has suggested that being in a group can significantly improve the ability of an individual to align toward and reach a target direction or point, even when all group members have limited navigational ability and there are no leaders. This effect is known as the "many-wrongs principle" since the large number of individual navigational errors across the group are suppressed by interactions and group cohesion. In this paper, we simulate the many-wrongs principle using a simple individual-based model of movement based on a biased random walk that includes group interactions. We study the ability of the group as a whole to reach a target given different levels of individual navigation error, group size, interaction radius, and environmental turbulence. In scenarios with low levels of environmental turbulence, simulation results demonstrate a navigational benefit from group membership, particularly for small group sizes. In contrast, when movement takes place in a highly turbulent environment, simulation results suggest that the best strategy is to navigate as individuals rather than as a group.

A policy of nuclear energy or energy conservation - on the construction of a wrong alternative

International Nuclear Information System (INIS)

Traube, K.

1981-01-01

From the content: a secret good-bye - wrong information from the energy experts - is there any priority for the efficient utilization of energie - do nuclear energy and energy conservation measures complement each other - the hidden socio-political dimensions - counter-information is necessary. (HP) [de

Production of wrong sign muons in neutrino-nucleon and antineutrino-nucleon collisions

International Nuclear Information System (INIS)

Onipchuk, A.B.

1988-01-01

The contribution is considered introduced by the quasipartonic mechanism to production of muons with a wrong sign in ν μ (ν-bar μ )N collisions. The ratios of muon production cross sections in the processes ν μ (ν-bar μ )N → μ + (μ - ) + ... to the inclusive cross sections have been calculated. Comparison to neutrino-nucleon data is made. The x and y distributions and mean kinematical characteristics of the scattered neutrinos are found

What's wrong with me? Coming to terms with same sex attraction.

Science.gov (United States)

Richardson, Brian

2011-10-01

Many, if not all, young people question what is wrong with them when they begin to realise that they are attracted to people of the same sex. This can be because of feelings of confusion, guilt and shame, which can develop in reaction to the society in which they live; feelings that are often mirrored by the families of the young people concerned. This article explains the theories behind sexuality to help nurses provide unprejudiced, appropriate support and information to children and young people seeking help.

Dynamic Sequence Assignment.

Science.gov (United States)

1983-12-01

D-136 548 DYNAMIIC SEQUENCE ASSIGNMENT(U) ADVANCED INFORMATION AND 1/2 DECISION SYSTEMS MOUNTAIN YIELW CA C A 0 REILLY ET AL. UNCLSSIIED DEC 83 AI/DS...I ADVANCED INFORMATION & DECISION SYSTEMS Mountain View. CA 94040 84 u ,53 V,..’. Unclassified _____ SCURITY CLASSIFICATION OF THIS PAGE REPORT...reviews some important heuristic algorithms developed for fas- ter solution of the sequence assignment problem. 3.1. DINAMIC MOGRAMUNIG FORMULATION FOR

Production of wrong-sign muons in neutrino-nucleon and antineutrino-nucleon collisions

International Nuclear Information System (INIS)

Onipchuk, A.B.; Choban, E.A.

1988-01-01

We consider the contribution of the quasiparton mechanism to the production of wrong-sign muons in ν/sub μ/(nu-bar/sub μ/)N collisions. We obtain the ratios of the production cross sections of muons in the processes ν/sub μ/(nu-bar/sub μ/)N→μ + (μ - )+... and the inclusive cross sections, and compare them with experiment in the case of neutrino-nucleon interactions. We find the x and y distributions and the average kinematical characteristics of the scattered neutrino

Dystopian Schools: Recovering Dewey's Radical Aesthetics in an Age of Utopia-Gone-Wrong

Science.gov (United States)

Heybach, Jessica A.; Sheffield, Eric C.

2014-01-01

In this article, we first suggest that contemporary school policies and practices represent a utopia-gone-wrong. In striving for an unattainable educational utopia--that is, all students will be proficient in math and reading by 2014--current polices and their resulting practices have brought a classic dystopian turn--the dehumanization of…

Legislative responses to wrongful conviction: Do partisan principals and advocacy efforts influence state-level criminal justice policy?

Science.gov (United States)

Kent, Stephanie L; Carmichael, Jason T

2015-07-01

The number of discovered wrongful criminal convictions (and resulting exonerations) has increased over the past decade. These cases erode public confidence in the criminal justice system and trust in the rule of law. Many states have adopted laws that aim to reduce system errors but no study has examined why some states appear more willing to provide due process protections against wrongful convictions than others. Findings from regression estimates suggest that states with a Republican controlled legislature or more Republican voters are less likely to pass these laws while the presence of advocacy organizations that are part of the 'innocence movement' make legislative change more likely. We thus identify important differences in the political and social context between U.S. states that influence the adoption of criminal justice policies. Copyright © 2015 Elsevier Inc. All rights reserved.

Forgotten Sunrise "Forgotten Sunrise. Behind The Abysmal Sky / Forever Sleeping Greystones". "The Moments When God Was Wrong" / Siim Nestor

Index Scriptorium Estoniae

Nestor, Siim, 1974-

2009-01-01

Arvustus: Forgotten Sunrise. Behind The Abysmal Sky / Forever Sleeping Greystones. [Tallinn] : Nailboard, 2009. Forgotten Sunrise. The Moments When God Was Wrong. [Tallinn] : Forgotten Sunrise, 2009. Uutest heliplaatidest

Description of methods for making activation detectors for use in nuclear reactors; Description des procedes de fabrication des detecteurs d'activation utilises dans les reacteurs nucleaires

Energy Technology Data Exchange (ETDEWEB)

Barbalat, R; Le Coguie, R; Leger, P; Salon, L; Thierry, M [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

1968-07-01

A brief description of methods currently used for making activation detectors, thin films and various deposits used in nuclear reactors. The thicknesses required vary from about a few tenths of a micron to a few tenths of a millimeter. Different techniques are used for fixing the large variety of elements: rolling, moulding, painting, electrolysis, vacuum deposition, thin films, wires, enamels, protective linings, etc. (authors) [French] Expose succinct des procedes actuellement mis en oeuvre pour la realisation des detecteurs d'activation, feuilles minces et depots divers utilises dans les reacteurs nucleaires. La gamme des epaisseurs necessaires s'etendant approximativement des dixiemes de micrometre aux dixiemes de millimetre. La diversite des elements a fixer justifiant les techniques differentes selon les cas: laminage, moulage, peinture, electrolyse, depot sous vide, couches minces, fils, emaux, revetements protecteurs, etc. (auteurs)

Using HL7 in hospital staff assignments.

Science.gov (United States)

Unluturk, Mehmet S

2014-02-01

Hospital staff assignments are the instructions that allocate the hospital staff members to the hospital beds. Currently, hospital administrators make the assignments without accessing the information regarding the occupancy of the hospital beds and the acuity of the patient. As a result, administrators cannot distinguish between occupied and unoccupied beds, and may therefore assign staff to unoccupied beds. This gives rise to uneven and inefficient staff assignments. In this paper, the hospital admission-discharge-transfer (ADT) system is employed both as a data source and an assignment device to create staff assignments. When the patient data is newly added or modified, the ADT system updates the assignment software client with the relevant data. Based on the relevant data, the assignment software client is able to construct staff assignments in a more efficient way. © 2013 Elsevier Ltd. All rights reserved.

Consensual exploitation : the moral wrong in exploitation and legal restrictions on consensual exploitative transactions

OpenAIRE

van der Neut, Wendy

2014-01-01

This thesis is about so-­‐called consensual exploitative transactions: transactions to which all parties agree voluntarily, and which are beneficial for all parties, but which are still widely considered exploitative, and for that reason legally restricted in many countries. The thesis asks two main questions: 1. What is wrong with consensual exploitation? 2.What implications does the answer to this question have for the legal restriction of consensual transactions ...

A note on ranking assignments using reoptimization

DEFF Research Database (Denmark)

Pedersen, Christian Roed; Nielsen, L.R.; Andersen, K.A.

2005-01-01

We consider the problem of ranking assignments according to cost in the classical linear assignment problem. An algorithm partitioning the set of possible assignments, as suggested by Murty, is presented where, for each partition, the optimal assignment is calculated using a new reoptimization...

Levels for Hotline Miami 2: Wrong Number Using Procedural Content Generations

Directory of Open Access Journals (Sweden)

Joseph Alexander Brown

2018-04-01

Full Text Available Procedural Content Generation is the automatic process for generating game content in order to allow for a decrease in developer resources while adding to the replayability of a digital game. It has been found to be highly effective as a method when utilized in rougelike games, of which Hotline Miami 2: Wrong Number shares a number of factors. Search based procedural content, in this case, a genetic algorithm, allows for the creation of levels which meet with a number of designer set requirements. The generator proposed provides for an automatic creation of game content for a commercially available game: the level design, object placement, and enemy placement.

Competitive Traffic Assignment in Road Networks

Directory of Open Access Journals (Sweden)

Krylatov Alexander Y.

2016-09-01

Full Text Available Recently in-vehicle route guidance and information systems are rapidly developing. Such systems are expected to reduce congestion in an urban traffic area. This social benefit is believed to be reached by imposing the route choices on the network users that lead to the system optimum traffic assignment. However, guidance service could be offered by different competitive business companies. Then route choices of different mutually independent groups of users may reject traffic assignment from the system optimum state. In this paper, a game theoretic approach is shown to be very efficient to formalize competitive traffic assignment problem with various groups of users in the form of non-cooperative network game with the Nash equilibrium search. The relationships between the Wardrop’s system optimum associated with the traffic assignment problem and the Nash equilibrium associated with the competitive traffic assignment problem are investigated. Moreover, some related aspects of the Nash equilibrium and the Wardrop’s user equilibrium assignments are also discussed.

Real life working shift assignment problem

Science.gov (United States)

Sze, San-Nah; Kwek, Yeek-Ling; Tiong, Wei-King; Chiew, Kang-Leng

2017-07-01

This study concerns about the working shift assignment in an outlet of Supermarket X in Eastern Mall, Kuching. The working shift assignment needs to be solved at least once in every month. Current approval process of working shifts is too troublesome and time-consuming. Furthermore, the management staff cannot have an overview of manpower and working shift schedule. Thus, the aim of this study is to develop working shift assignment simulation and propose a working shift assignment solution. The main objective for this study is to fulfill manpower demand at minimum operation cost. Besides, the day off and meal break policy should be fulfilled accordingly. Demand based heuristic is proposed to assign working shift and the quality of the solution is evaluated by using the real data.

Right and Wrong and Cultural Diversity: Replication of the 2002 NAS/Zogby Poll on Business Ethics

Science.gov (United States)

Ludlum, Marty; Mascaloinov, Sergei

2004-01-01

In April 2002, a NAS/Zogby poll found that only a quarter of sampled students perceived uniform standards of "right and wrong" and that most students felt that ethical behavior depends on cultural diversity. In this effort to replicate those findings in a larger sample of American college students, the authors obtained results that…

24 CFR 221.770 - Assignment option.

Science.gov (United States)

2010-04-01

... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Assignment option. 221.770 Section... § 221.770 Assignment option. A mortgagee holding a conditional or firm commitment issued on or before... mortgagee's approved underwriter on or before November 30, 1983) has the option to assign, transfer and...

Job Assignments under Moral Hazard

DEFF Research Database (Denmark)

Koch, Alexander; Nafziger, Julia

Inefficient job assignments are usually explained with incomplete information about employees' abilities or contractual imperfections. We show that inefficient assignments arise even without uncertainty about the employee's ability and with complete contracts. Building on this result we provide...

EZ-ASSIGN, a program for exhaustive NMR chemical shift assignments of large proteins from complete or incomplete triple-resonance data

Energy Technology Data Exchange (ETDEWEB)

Zuiderweg, Erik R. P., E-mail: zuiderwe@umich.edu; Bagai, Ireena [The University of Michigan Medical School, Department of Biological Chemistry (United States); Rossi, Paolo [Rutgers University, Center for Integrative Proteomics Research (United States); Bertelsen, Eric B. [Arbor Communications, Inc. (United States)

2013-10-15

For several of the proteins in the BioMagResBank larger than 200 residues, 60 % or fewer of the backbone resonances were assigned. But how reliable are those assignments? In contrast to complete assignments, where it is possible to check whether every triple-resonance Generalized Spin System (GSS) is assigned once and only once, with incomplete data one should compare all possible assignments and pick the best one. But that is not feasible: For example, for 200 residues and an incomplete set of 100 GSS, there are 1.6 Multiplication-Sign 10{sup 260} possible assignments. In 'EZ-ASSIGN', the protein sequence is divided in smaller unique fragments. Combined with intelligent search approaches, an exhaustive comparison of all possible assignments is now feasible using a laptop computer. The program was tested with experimental data of a 388-residue domain of the Hsp70 chaperone protein DnaK and for a 351-residue domain of a type III secretion ATPase. EZ-ASSIGN reproduced the hand assignments. It did slightly better than the computer program PINE (Bahrami et al. in PLoS Comput Biol 5(3):e1000307, 2009) and significantly outperformed SAGA (Crippen et al. in J Biomol NMR 46:281-298, 2010), AUTOASSIGN (Zimmerman et al. in J Mol Biol 269:592-610, 1997), and IBIS (Hyberts and Wagner in J Biomol NMR 26:335-344, 2003). Next, EZ-ASSIGN was used to investigate how well NMR data of decreasing completeness can be assigned. We found that the program could confidently assign fragments in very incomplete data. Here, EZ-ASSIGN dramatically outperformed all the other assignment programs tested.

24 CFR 221.255 - Assignment option.

Science.gov (United States)

2010-04-01

... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Assignment option. 221.255 Section... Assignment option. (a) A mortgagee holding a mortgage insured pursuant to a conditional or firm commitment issued on or before November 30, 1983 has the option to assign, transfer and deliver to the Commissioner...

An algorithm for ranking assignments using reoptimization

DEFF Research Database (Denmark)

Pedersen, Christian Roed; Nielsen, Lars Relund; Andersen, Kim Allan

2008-01-01

We consider the problem of ranking assignments according to cost in the classical linear assignment problem. An algorithm partitioning the set of possible assignments, as suggested by Murty, is presented where, for each partition, the optimal assignment is calculated using a new reoptimization...... technique. Computational results for the new algorithm are presented...

48 CFR 42.602 - Assignment and location.

Science.gov (United States)

2010-10-01

... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Assignment and location... Assignment and location. (a) A CACO may be assigned only when (1) the contractor has at least two locations..., or a full-time CACO may be assigned. In determining the location of the CACO, the responsible agency...

Study of various processes for marking sediments with gold-198; Etude de divers procedes de marquages de sediments par l'or 198

Energy Technology Data Exchange (ETDEWEB)

Jeanneau, B [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

1967-12-15

The use of radioactive isotopes for the study of sediment deposits is based mainly on two methods: marking in the mass - a glass of an element which can be activated replaces the sediment; surface marking - a physico-chemical process is used to deposit a radio-element at the surface of the sediment. The second process is used in particular for sands when it is advantageous to have a large number of particles for statistical analysis. The aim of this work was to develop a rapid and simple method of marking which could be applied on the actual site of the experiment where equipment, may be limited. The method recommended for marking sand with gold-198 is a combination of the Petersen (treatment with tin chloride) and Campbell (treatment with silver) methods combined with prior treatments with nitric acid and caustic soda. Using this method it is possible to deposit 125 mg of gold per kilo of sediment with a yield of 95 per cent (i.e. 10 Ci/kg) using a hydrochloric acid solution containing gold. The problem of the solidity of the deposits, of their value and of their reproducibility is discussed from the point of view of the mineral constitution of the sand. (author) [French] L'utilisation d'isotopes radioactifs pour l'etude des deplacements sedimentaires fait, principalement appel a deux methodes: le marquage massique - un verre contenant un element activable remplace le sediment; le marquage superficiel - un traitement physico-chimique permet de deposer un radioelement a la surface du sediment. Le second procede est surtout employe pour les sables lorsqu'il est utile de disposer d'un grand nombre de grains pour des raisons statistiques. Le but de ce travail etait de mettre au point une methode simple et rapide de marquage pouvant etre appliquee sur le site meme de l'experience pour les utilisateurs disposant d'un equipement limite. Le procede preconise pour le marquage des sables par l'or 198 est une combinaison des methodes Petersen (traitement au chlorure d

EZ-ASSIGN, a program for exhaustive NMR chemical shift assignments of large proteins from complete or incomplete triple-resonance data

International Nuclear Information System (INIS)

Zuiderweg, Erik R. P.; Bagai, Ireena; Rossi, Paolo; Bertelsen, Eric B.

2013-01-01

For several of the proteins in the BioMagResBank larger than 200 residues, 60 % or fewer of the backbone resonances were assigned. But how reliable are those assignments? In contrast to complete assignments, where it is possible to check whether every triple-resonance Generalized Spin System (GSS) is assigned once and only once, with incomplete data one should compare all possible assignments and pick the best one. But that is not feasible: For example, for 200 residues and an incomplete set of 100 GSS, there are 1.6 × 10 260 possible assignments. In “EZ-ASSIGN”, the protein sequence is divided in smaller unique fragments. Combined with intelligent search approaches, an exhaustive comparison of all possible assignments is now feasible using a laptop computer. The program was tested with experimental data of a 388-residue domain of the Hsp70 chaperone protein DnaK and for a 351-residue domain of a type III secretion ATPase. EZ-ASSIGN reproduced the hand assignments. It did slightly better than the computer program PINE (Bahrami et al. in PLoS Comput Biol 5(3):e1000307, 2009) and significantly outperformed SAGA (Crippen et al. in J Biomol NMR 46:281–298, 2010), AUTOASSIGN (Zimmerman et al. in J Mol Biol 269:592–610, 1997), and IBIS (Hyberts and Wagner in J Biomol NMR 26:335–344, 2003). Next, EZ-ASSIGN was used to investigate how well NMR data of decreasing completeness can be assigned. We found that the program could confidently assign fragments in very incomplete data. Here, EZ-ASSIGN dramatically outperformed all the other assignment programs tested

Reductions without Regret: Avoiding Wrong Turns, Roach Motels, and Box Canyons

Energy Technology Data Exchange (ETDEWEB)

Swegle, John A. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL); Tincher, Douglas J. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL)

2013-09-11

This is the third of three papers (in addition to an introductory summary) aimed at providing a framework for evaluating future reductions or modifications of the U.S. nuclear force, first by considering previous instances in which nuclear-force capabilities were eliminated; second by looking forward into at least the foreseeable future at the features of global and regional deterrence (recognizing that new weapon systems currently projected will have expected lifetimes stretching beyond our ability to predict the future); and third by providing examples of past or possible undesirable outcomes in the shaping of the future nuclear force, as well as some closing thoughts for the future. In this paper, we provide one example each of our judgments on what constitutes a box canyon, a roach motel, and a wrong turn: Wrong Turn: The Reliable Replacement Warhead: Roach Motel: SRAM T vs the B61: and A Possible Box Canyon: A Low-Yield Version of the W76 SLBM Warhead. Recognizing that new nuclear missions or weapons are not demanded by current circumstances ₋ a development path that yields future capabilities similar to those of today, which are adequate if not always ideal, and a broader national-security strategy that supports nonproliferation and arms control by reducing the role for, and numbers, of nuclear weapons ₋ we briefly consider alternate, less desirable futures, and their possible effect on the complex problem of regional deterrence. In this regard, we discuss the issues posed by, and possible responses to, three example regional deterrence challenges: in-country defensive use of nuclear weapons by an adversary; reassurance of U.S. allies with limited strategic depth threatened by an emergent nuclear power; and extraterritorial, non-strategic offensive use of nuclear weapons by an adversary in support of limited military objectives against a U.S. ally.

Electrohydrodynamics: a high-voltage direct energy conversion process; L'electrohydrodynamique: Un procede de conversion directe d'energie a haute tension

Energy Technology Data Exchange (ETDEWEB)

Brun, S [Commissariat a l' Energie Atomique, Grenoble (France). Centre d' Etudes Nucleaires

1967-04-15

This analysis consists of a theoretical and practical study of a high-tension electrical power generator based on the Van de Graaff generator principle, the main difference being that the charges produced are transported by a gas in motion and not by a belt. The electrical and thermal properties of such a generator are studied, as well as the difficult problem of the production of the ionised particles used in the conversion. A certain number of results already published on this process for converting kinetic energy into electrical energy is given, as well as some possible applications in the field of space technology. (author) [French] Cette analyse est une etude theorique et pratique d'un generateur de puissance electrique a haute tension, base sur le principe du generateur Van de Graaff, la difference principale etant que les charges produites sont transportees pur un gaz en mouvement et non par une courroie. Les proprietes electriques et thermiques d'un tel generateur sont etudiees ainsi que le probleme delicat de la production des particules ionisees utilisees dans la conversion. Un certain nombre de resultats publies sur ce procede de conversion d'energie cinetique en energie electrique sont reproduits, ainsi que les applications possibles aux problemes spatiaux. (auteur)

UF{sub 6} tiedowns for truck transport - right way/wrong way

Energy Technology Data Exchange (ETDEWEB)

Stout, F.W. Jr. [Martin Marietta Energy Systems, Inc., Oak Ridge, TN (United States)

1991-12-31

Tiedown systems for truck transport of UF{sub 6} must be defined and controlled to assure the least risk for hauling the material over the highways. This paper and an associated poster display will present the current status of regulatory criteria for tiedowns, analyze the structural stresses involved in tiedowns for two major UF{sub 6} packaging systems, the 21PF series of overpacks and the 48 in. diameter shipping cylinders, and will present photographs showing some {open_quote}right ways{close_quotes} and some {open_quotes}wrong (or risky) ways{close_quotes} currently used for tiedown systems. Risky tiedown methods must be replaced with safer less risky methods to insure the safe transport of UF{sub 6}.

Exogenous spatial attention influences figure-ground assignment.

Science.gov (United States)

Vecera, Shaun P; Flevaris, Anastasia V; Filapek, Joseph C

2004-01-01

In a hierarchical stage account of vision, figure-ground assignment is thought to be completed before the operation of focal spatial attention. Results of previous studies have supported this account by showing that unpredictive, exogenous spatial precues do not influence figure-ground assignment, although voluntary attention can influence figure-ground assignment. However, in these studies, attention was not summoned directly to a region in a figure-ground display. In three experiments, we addressed the relationship between figure-ground assignment and visuospatial attention. In Experiment 1, we replicated the finding that exogenous precues do not influence figure-ground assignment when they direct attention outside of a figure-ground stimulus. In Experiment 2, we demonstrated that exogenous attention can influence figure-ground assignment if it is directed to one of the regions in a figure-ground stimulus. In Experiment 3, we demonstrated that exogenous attention can influence figure-ground assignment in displays that contain a Gestalt figure-ground cue; this result suggests that figure-ground processes are not entirely completed prior to the operation of focal spatial attention. Exogenous spatial attention acts as a cue for figure-ground assignment and can affect the outcome of figure-ground processes.

Do Insurers Have to Pay for Bad Behaviour in Settling Claims? Legal Aspects of Insurers' Wrongful Claims Handling

NARCIS (Netherlands)

W.H. van Boom (Willem)

2011-01-01

textabstractAbstract: This article presents a comparative legal analysis of wrongful claims handling by insurance companies in indemnity and liability insurance. From the outset, it is clear that it may be difficult to draw the line between legitimate claims denial and refusal to pay, on the one

Self-Defence as a Circumstance Precluding the Wrongfulness of the Use of Force

Directory of Open Access Journals (Sweden)

Cliff Farhang

2015-07-01

Full Text Available Roberto Ago, the International Law Commission’s second Special Rapporteur on the topic of state responsibility for internationally wrongful acts, defined self-defence as a faculté of a state to use force in response to an act of another state through which a breach of the principal obligation under Article 2(4 Charter is committed. On this basis, he then inserted a provision in Chapter V to Part One of the Draft Articles on State Responsibility expressing self-defence as a specific factual circumstance precluding the wrongfulness of the use of force which constitutes a response to state aggression. This conception of self-defence, although misunderstood from the onset, remained in the backdrop of the study of the law of state responsibility for a considerable period. It was only dismantled during the reign of the last Special Rapporteur on the topic of state responsibility, James Crawford. The last Rapporteur, at the onset, submitted that it is not the function of the Draft Articles to specify the content of the primary rules, including that referred to in Article 51 Charter. He then redefined the function of the circumstance of self-defence as that of precluding the wrongfulness of non-performance of certain obligations other than the general prohibition insofar as such non-performance is connected with the exercise of the right under Article 51 Charter.This contribution first scrutinises this paradigmatic shift and finds it to be symptomatic of the conviction on the part of Crawford that the notion of self-defence could also encompass the use of force against speculative threats of state origin as well as actual threats that emanate from individuals or groups which are disconnected from the organisation of any state. It then uses this finding as a springboard towards the examination of the controversy surrounding the notion of self-defence under international law. In that connection, it first outlines the findings of the World Court on the

WebAssign: Assessing Your Students' Understanding Continuously

Science.gov (United States)

Risley, John S.

1999-11-01

Motivating students to learn is a constant challenge for faculty. Technology can play a significant role. One such solution is WebAssign — a web-based homework system that offers new teaching and learning opportunities for educators and their students. WebAssign delivers, collects, grades, and records customized homework assignments over the Internet. Students get immediate feedback with credit and instructors can implement "Just-in-Time" teaching. In this talk, I will describe how assignments can be generated with different numerical values for each question, giving each student a unique problem to solve. This feature encourages independent thinking with the benefit of collaborative learning. Example assignments taken from textbook questions and intellectually engaging Java applet simulations will be shown. Studies and first-hand experience on the educational impact of using WebAssign will also be discussed.

Abandoning the common law: medical negligence, genetic tests and wrongful life in the Australian High Court.

Science.gov (United States)

Faunce, Thomas; Jefferys, Susannah

2007-05-01

The Australian High Court recently found that the common law could allow parents to claim tortious damages when medical negligence was proven to have led to the birth of an unplanned, but healthy, baby (Cattanach v Melchior (2003) 215 CLR 1). In Harriton v Stephens (2006) 80 ALJR 791; [2006] HCA 15 and Waller v James; Waller v Hoolahan (2006) 80 ALJR 846; [2006] HCA 16 the High Court in a six-to-one decision (Kirby J dissenting) decided that no such claim could be made by a child when medical negligence in failing to order an in utero genetic test caused the child severe disability. In an era when almost all pregnancies will soon require patented fetal genetic tests as part of the professional standard of care, the High Court, by barring so-called "wrongful life" (better termed "wrongful suffering") claims, may have created a partial immunity from suit for their corporate manufacturers and the doctors who administer them. What lessons can be learnt from this case about how the Australian High Court is, or should be, approaching medical negligence cases and its role as guardian of the Australian common law?

More than words: patients' views on apology and disclosure when things go wrong in cancer care.

Science.gov (United States)

Mazor, Kathleen M; Greene, Sarah M; Roblin, Douglas; Lemay, Celeste A; Firneno, Cassandra L; Calvi, Josephine; Prouty, Carolyn D; Horner, Kathryn; Gallagher, Thomas H

2013-03-01

Guidelines on apology and disclosure after adverse events and errors have been in place for over 5 years. This study examines whether patients consider recommended responses to be appropriate and desirable, and whether clinicians' actions after adverse events are consistent with recommendations. Patients who believed that something had gone wrong during their cancer care were identified. During in-depth interviews, patients described the event, clinicians' responses, and their reactions. 78 patients were interviewed. Patients' valued apology and expressions of remorse, empathy and caring, explanation, acknowledgement of responsibility, and efforts to prevent recurrences, but these key elements were often missing. For many patients, actions and evidence of clinician learning were most important. Patients' reports of apology and disclosure when they believe something has gone wrong in their care suggest that clinicians' responses continue to fall short of expectations. Clinicians preparing to talk with patients after an adverse event or medical error should be aware that patients expect their actions to be congruent with their words of apology and caring. Healthcare systems need to support clinicians throughout the disclosure process, and facilitate both system and individual learning to prevent recurrences. Copyright © 2011 Elsevier Ireland Ltd. All rights reserved.

The 'nightmare' of wrong level in spine surgery: a critical appraisal

Directory of Open Access Journals (Sweden)

Irace Claudio

2012-06-01

Full Text Available Abstract The recent article published in the Journal by Lindley and colleagues (Patient Saf. Surg. 2011, 5:33 reported the successful surgical treatment of a persistent thoracic pain following a T7-8 microdiscectomy, truly performed at the ‘level immediately above’. The wrong level in spine surgery is a multi-factorial matter and several strategies have been designed and adopted to try decreasing its occurrence. We think that three of these factors are crucial: global strategy, attention, precision in level identification; and the actors we identified are the surgeon, the assistant nurse and the (neuroradiologist respectively. Basing upon our experience, the role of the radiologist pre- and intraoperatively and the importance of the assistant nurse are briefly described.

Solving the rectangular assignment problem and applications

NARCIS (Netherlands)

Bijsterbosch, J.; Volgenant, A.

2010-01-01

The rectangular assignment problem is a generalization of the linear assignment problem (LAP): one wants to assign a number of persons to a smaller number of jobs, minimizing the total corresponding costs. Applications are, e.g., in the fields of object recognition and scheduling. Further, we show

7 CFR 900.106 - Assignment of mediator.

Science.gov (United States)

2010-01-01

... 7 Agriculture 8 2010-01-01 2010-01-01 false Assignment of mediator. 900.106 Section 900.106 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing... Assignment of mediator. The Director of the Division shall assign a mediator, from the group designated by...

My Favorite Assignment.

Science.gov (United States)

ABCA Bulletin, 1983

1983-01-01

Describes three assignments for enticing business communication students to undertake library research: an analysis of a Fortune 500 company, a career choice report, and a report on an organization that offers potential employment. (AEA)

27 CFR 70.227 - Suspension of running of period of limitation; wrongful seizure of property of third party.

Science.gov (United States)

2010-04-01

... 27 Alcohol, Tobacco Products and Firearms 2 2010-04-01 2010-04-01 false Suspension of running of... Limitations § 70.227 Suspension of running of period of limitation; wrongful seizure of property of third party. The running of the period of limitations on collection after assessment prescribed in 26 U.S.C...

A Troubling Success Story: Revisiting a Classic Deviance Assignment in a Criminology Course.

Science.gov (United States)

Bordt, Rebecca L.

2001-01-01

Focuses on an adapted version of the classic deviance exercise used in a criminology course taught from 1992 to 2000. Describes how the exercise typically worked, but also discusses a time when the exercise went wrong. Addresses what lessons were learned from that experience. (CMK)

Managing voluntary turnover through challenging assignments

NARCIS (Netherlands)

Preenen, P.T.Y.; de Pater, I.E.; van Vianen, A.E.M.; Keijzer, L.

2011-01-01

This study examines employees’ challenging assignments as manageable means to reduce turnover intentions, job search behaviors, and voluntary turnover. Results indicate that challenging assignments are negatively related to turnover intentions and job search behaviors and that these relationships

Managing voluntary turnover through challenging assignments

NARCIS (Netherlands)

Preenen, P.T.Y.; Pater, I.E. de; Vianen, A.E.M. van; Keijzer, L.

2011-01-01

This study examines employees' challenging assignments as manageable means to reduce turnover intentions, job search behaviors, and voluntary turnover. Results indicate that challenging assignments are negatively related to turnover intentions and job search behaviors and that these relationships

Scaffolding students’ assignments

DEFF Research Database (Denmark)

Slot, Marie Falkesgaard

2013-01-01

This article discusses scaffolding in typical student assignments in mother tongue learning materials in upper secondary education in Denmark and the United Kingdom. It has been determined that assignments do not have sufficient scaffolding end features to help pupils understand concepts and build...... objects. The article presents the results of empirical research on tasks given in Danish and British learning materials. This work is based on a further development of my PhD thesis: “Learning materials in the subject of Danish” (Slot 2010). The main focus is how cognitive models (and subsidiary explicit...... learning goals) can help students structure their argumentative and communica-tive learning processes, and how various multimodal representations can give more open-ended learning possibilities for collaboration. The article presents a short introduction of the skills for 21st century learning and defines...

The childcare panopticon: guidelines for preventing child sexual abuse and wrongful allegations of child sexual abuse in Danish childcare institutions

DEFF Research Database (Denmark)

Leander, Else-Marie Buch; Larsen, Per Lindsø; Munk, Karen

2018-01-01

This article presents the first research study of guidelines in Danish childcare institutions for protecting children against sexual abuse (CSA), and staff against wrongful allegations of CSA. Worldwide, it represents one of few empirical studies of the unintended consequences of contemporary soc...

Mars - robust automatic backbone assignment of proteins

International Nuclear Information System (INIS)

Jung, Young-Sang; Zweckstetter, Markus

2004-01-01

MARS a program for robust automatic backbone assignment of 13 C/ 15 N labeled proteins is presented. MARS does not require tight thresholds for establishing sequential connectivity or detailed adjustment of these thresholds and it can work with a wide variety of NMR experiments. Using only 13 C α / 13 C β connectivity information, MARS allows automatic, error-free assignment of 96% of the 370-residue maltose-binding protein. MARS can successfully be used when data are missing for a substantial portion of residues or for proteins with very high chemical shift degeneracy such as partially or fully unfolded proteins. Other sources of information, such as residue specific information or known assignments from a homologues protein, can be included into the assignment process. MARS exports its result in SPARKY format. This allows visual validation and integration of automated and manual assignment

Assignment of element and isotope factors

International Nuclear Information System (INIS)

Schneider, R.A.

1984-01-01

Element and isotope factors are assigned in the NICS internal accounting system at the Exxon Fuel Fabrication Facility on the basis of coded information included on the material transfer documents. This paper explains more fully the manner in which NICS assigns these factors

Necessity as a ground for precluding wrongfulness in international investment law

Directory of Open Access Journals (Sweden)

Vasiljević Mirko

2016-01-01

Full Text Available The issue of necessity as a ground for precluding wrongfulness has received close attention over the last two decades both in case law and in scholarly writings. Arbitrations conducted against Argentina for breaches of bilateral investment treaty obligations committed while fighting against economic crisis revived the old controversies related to the concept of necessity in general public international law, but also brought up some new dilemmas. This paper analyses the use of necessity in international investment law in light of what the authors suggest to be the legal purpose of this concept, points to and discusses the divergences in case law with respect to some of the elements of the defence based on necessity and offers the solutions susceptible to lead to a more harmonious understanding of necessity in international investment law.

Inferential backbone assignment for sparse data

International Nuclear Information System (INIS)

Vitek, Olga; Bailey-Kellogg, Chris; Craig, Bruce; Vitek, Jan

2006-01-01

This paper develops an approach to protein backbone NMR assignment that effectively assigns large proteins while using limited sets of triple-resonance experiments. Our approach handles proteins with large fractions of missing data and many ambiguous pairs of pseudoresidues, and provides a statistical assessment of confidence in global and position-specific assignments. The approach is tested on an extensive set of experimental and synthetic data of up to 723 residues, with match tolerances of up to 0.5 ppm for C α and C β resonance types. The tests show that the approach is particularly helpful when data contain experimental noise and require large match tolerances. The keys to the approach are an empirical Bayesian probability model that rigorously accounts for uncertainty in the data at all stages in the analysis, and a hybrid stochastic tree-based search algorithm that effectively explores the large space of possible assignments

32 CFR 884.2 - Assigned responsibilities.

Science.gov (United States)

2010-07-01

... OF PERSONNEL TO UNITED STATES CIVILIAN AUTHORITIES FOR TRIAL § 884.2 Assigned responsibilities. (a... 32 National Defense 6 2010-07-01 2010-07-01 false Assigned responsibilities. 884.2 Section 884.2... requests for return of members to the United States for delivery to civilian authorities when the request...

Personnel dose assignment practices

International Nuclear Information System (INIS)

Fix, J.J.

1993-04-01

Implementation of DOE N 5480.6 Radiological Control Manual Article 511(3) requirements, to minimize the assignment of personnel dosimeters, should be done only under a broader context ensuring that capabilities are in place to monitor and record personnel exposure both for compliance and for potential litigation. As noted in NCRP Report No. 114, personnel dosimetry programs are conducted to meet four major objectives: radiation safety program control and evaluation; regulatory compliance; epidemiological research; and litigation. A change to Article 511(3) is proposed that would require that minimizing the assignment of personnel dosimeters take place only following full evaluation of overall capabilities (e.g., access control, area dosimetry, etc.) to meet the NCRP objectives

Computational Aspects of Assigning Agents to a Line

DEFF Research Database (Denmark)

Aziz, Haris; Hougaard, Jens Leth; Moreno-Ternero, Juan D.

2017-01-01

-egalitarian assignments. The approach relies on an algorithm which is shown to be faster than general purpose algorithms for the assignment problem. We also extend the approach to probabilistic assignments and explore the computational features of existing, as well as new, methods for this setting....

Computational aspects of assigning agents to a line

DEFF Research Database (Denmark)

Aziz, Haris; Hougaard, Jens Leth; Moreno-Ternero, Juan D.

2017-01-01

-egalitarian assignments. The approach relies on an algorithm which is shown to be faster than general purpose algorithms for the assignment problem. We also extend the approach to probabilistic assignments and explore the computational features of existing, as well as new, methods for this setting....

Measuring Vocational Preferences: Ranking versus Categorical Rating Procedures.

Science.gov (United States)

Carifio, James

1978-01-01

Describes a study to compare the relative validities of ranking v categorical rating procedures for obtaining student vocational preference data in exploratory program assignment situations. Students indicated their vocational program preferences from career clusters, and the frequency of wrong assignments made by each method was analyzed. (MF)

A Computerized Approach to Trickle-Process, Random Assignment.

Science.gov (United States)

Braucht, G. Nicholas; Reichardt, Charles S.

1993-01-01

Procedures for implementing random assignment with trickle processing and ways they can be corrupted are described. A computerized method for implementing random assignment with trickle processing is presented as a desirable alternative in many situations and a way of protecting against threats to assignment validity. (SLD)

Precision Oncology: Between Vaguely Right and Precisely Wrong.

Science.gov (United States)

Brock, Amy; Huang, Sui

2017-12-01

Precision Oncology seeks to identify and target the mutation that drives a tumor. Despite its straightforward rationale, concerns about its effectiveness are mounting. What is the biological explanation for the "imprecision?" First, Precision Oncology relies on indiscriminate sequencing of genomes in biopsies that barely represent the heterogeneous mix of tumor cells. Second, findings that defy the orthodoxy of oncogenic "driver mutations" are now accumulating: the ubiquitous presence of oncogenic mutations in silent premalignancies or the dynamic switching without mutations between various cell phenotypes that promote progression. Most troublesome is the observation that cancer cells that survive treatment still will have suffered cytotoxic stress and thereby enter a stem cell-like state, the seeds for recurrence. The benefit of "precision targeting" of mutations is inherently limited by this counterproductive effect. These findings confirm that there is no precise linear causal relationship between tumor genotype and phenotype, a reminder of logician Carveth Read's caution that being vaguely right may be preferable to being precisely wrong. An open-minded embrace of the latest inconvenient findings indicating nongenetic and "imprecise" phenotype dynamics of tumors as summarized in this review will be paramount if Precision Oncology is ultimately to lead to clinical benefits. Cancer Res; 77(23); 6473-9. ©2017 AACR . ©2017 American Association for Cancer Research.

Writing Assignments that Promote Active Learning

Science.gov (United States)

Narayanan, M.

2014-12-01

Encourage students to write a detailed, analytical report correlating classroom discussions to an important historical event or a current event. Motivate students interview an expert from industry on a topic that was discussed in class. Ask the students to submit a report with supporting sketches, drawings, circuit diagrams and graphs. Propose that the students generate a complete a set of reading responses pertaining to an assigned topic. Require each student to bring in one comment or one question about an assigned reading. The assignment should be a recent publication in an appropriate journal. Have the students conduct a web search on an assigned topic. Ask them to generate a set of ideas that can relate to classroom discussions. Provide the students with a study guide. The study guide should provide about 10 or 15 short topics. Quiz the students on one or two of the topics. Encourage the students to design or develop some creative real-world examples based on a chapter discussed or a topic of interest. Require that students originate, develop, support and defend a viewpoint using a specifically assigned material. Make the students practice using or utilizing a set of new technical terms they have encountered in an assigned chapter. Have students develop original examples explaining the different terms. Ask the students to select one important terminology from the previous classroom discussions. Encourage the students to explain why they selected that particular word. Ask them to talk about the importance of the terminology from the point of view of their educational objectives and future career. Angelo, T. A. (1991). Ten easy pieces: Assessing higher learning in four dimensions. In T. A. Angelo (Ed.), Classroom research: Early lessons from success (pp. 17-31). New Directions for Teaching and Learning, No. 46. San Francisco: Jossey-Bass.

Detecting Plagiarism in MS Access Assignments

Science.gov (United States)

Singh, Anil

2013-01-01

Assurance of individual effort from students in computer-based assignments is a challenge. Due to digitization, students can easily use a copy of their friend's work and submit it as their own. Plagiarism in assignments puts students who cheat at par with those who work honestly and this compromises the learning evaluation process. Using a…

Wrong-site nerve blocks: A systematic literature review to guide principles for prevention.

Science.gov (United States)

Deutsch, Ellen S; Yonash, Robert A; Martin, Donald E; Atkins, Joshua H; Arnold, Theresa V; Hunt, Christina M

2018-05-01

Wrong-site nerve blocks (WSBs) are a significant, though rare, source of perioperative morbidity. WSBs constitute the most common type of perioperative wrong-site procedure reported to the Pennsylvania Patient Safety Authority. This systematic literature review aggregates information about the incidence, patient consequences, and conditions that contribute to WSBs, as well as evidence-based methods to prevent them. A systematic search of English-language publications was performed, using the PRISMA process. Seventy English-language publications were identified. Analysis of four publications reporting on at least 10,000 blocks provides a rate of 0.52 to 5.07 WSB per 10,000 blocks, unilateral blocks, or "at risk" procedures. The most commonly mentioned potential consequence was local anesthetic toxicity. The most commonly mentioned contributory factors were time pressure, personnel factors, and lack of site-mark visibility (including no site mark placed). Components of the block process that were addressed include preoperative nerve-block verification, nerve-block site marking, time-outs, and the healthcare facility's structure and culture of safety. A lack of uniform reporting criteria and divergence in the data and theories presented may reflect the variety of circumstances affecting when and how nerve blocks are performed, as well as the infrequency of a WSB. However, multiple authors suggest three procedural steps that may help to prevent WSBs: (1) verify the nerve-block procedure using multiple sources of information, including the patient; (2) identify the nerve-block site with a visible mark; and (3) perform time-outs immediately prior to injection or instillation of the anesthetic. Hospitals, ambulatory surgical centers, and anesthesiology practices should consider creating site-verification processes with clinician input and support to develop sustainable WSB-prevention practices. Copyright © 2017 Elsevier Inc. All rights reserved.

Quantum entanglement: facts and fiction - how wrong was Einstein after all?

Science.gov (United States)

Nordén, Bengt

2016-01-01

Einstein was wrong with his 1927 Solvay Conference claim that quantum mechanics is incomplete and incapable of describing diffraction of single particles. However, the Einstein-Podolsky-Rosen paradox of entangled pairs of particles remains lurking with its 'spooky action at a distance'. In molecules quantum entanglement can be viewed as basis of both chemical bonding and excitonic states. The latter are important in many biophysical contexts and involve coupling between subsystems in which virtual excitations lead to eigenstates of the total Hamiltonian, but not for the separate subsystems. The author questions whether atomic or photonic systems may be probed to prove that particles or photons may stay entangled over large distances and display the immediate communication with each other that so concerned Einstein. A dissociating hydrogen molecule is taken as a model of a zero-spin entangled system whose angular momenta are in principle possible to probe for this purpose. In practice, however, spins randomize as a result of interactions with surrounding fields and matter. Similarly, no experiment seems yet to provide unambiguous evidence of remaining entanglement between single photons at large separations in absence of mutual interaction, or about immediate (superluminal) communication. This forces us to reflect again on what Einstein really had in mind with the paradox, viz. a probabilistic interpretation of a wave function for an ensemble of identically prepared states, rather than as a statement about single particles. Such a prepared state of many particles would lack properties of quantum entanglement that make it so special, including the uncertainty upon which safe quantum communication is assumed to rest. An example is Zewail's experiment showing visible resonance in the dissociation of a coherently vibrating ensemble of NaI molecules apparently violating the uncertainty principle. Einstein was wrong about diffracting single photons where space-like anti

Flexible taxonomic assignment of ambiguous sequencing reads

Directory of Open Access Journals (Sweden)

Jansson Jesper

2011-01-01

Full Text Available Abstract Background To characterize the diversity of bacterial populations in metagenomic studies, sequencing reads need to be accurately assigned to taxonomic units in a given reference taxonomy. Reads that cannot be reliably assigned to a unique leaf in the taxonomy (ambiguous reads are typically assigned to the lowest common ancestor of the set of species that match it. This introduces a potentially severe error in the estimation of bacteria present in the sample due to false positives, since all species in the subtree rooted at the ancestor are implicitly assigned to the read even though many of them may not match it. Results We present a method that maps each read to a node in the taxonomy that minimizes a penalty score while balancing the relevance of precision and recall in the assignment through a parameter q. This mapping can be obtained in time linear in the number of matching sequences, because LCA queries to the reference taxonomy take constant time. When applied to six different metagenomic datasets, our algorithm produces different taxonomic distributions depending on whether coverage or precision is maximized. Including information on the quality of the reads reduces the number of unassigned reads but increases the number of ambiguous reads, stressing the relevance of our method. Finally, two measures of performance are described and results with a set of artificially generated datasets are discussed. Conclusions The assignment strategy of sequencing reads introduced in this paper is a versatile and a quick method to study bacterial communities. The bacterial composition of the analyzed samples can vary significantly depending on how ambiguous reads are assigned depending on the value of the q parameter. Validation of our results in an artificial dataset confirm that a combination of values of q produces the most accurate results.

First Trimester Fetal Gender Assignment by Ultrasound

Directory of Open Access Journals (Sweden)

Sabahattin Altunyurt

2010-03-01

Full Text Available Objective: To investigate the efficiency of genital tubercule angle on detecting fetal gender in first trimester by ultrasonography. Material-Method: Fetal sex assignment by ultrasound was carried out in 172 pregnancies at 11-13+6 weeks between 2007 June and 2007 December. Gestational age was determined by the measurement of crown-rump length (CRL. The ultrasound predictions were compared with actual sex at birth. Mid-sagittal planes of a section of the fetal genital tubercle were performed to identify the gender. Results: 155 of 172 patients’ data were achieved. The overall success rate was 92.3 % in sonographic assignment of fetal sex. The correct assignment rate in female fetuses was significantly higher than males (95.9 % - 88.8 % [p=0,001]. The correct identification of fetal sex improved with advancing gestational age from 89.3 % between 11-11+6 weeks, 92.5 % between 12-12+6 weeks and 93.4 % between 13-13+6 weeks (p=0,96. Conclusion: The fetal sex assignment by ultrasonography between 11-13+6 weeks had high success rate. The sensitivity of fetal sex assignment was not affected with fetus position and gestational age.

Historical WBAN ID Assignments

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — 4"x6" index cards represent the first written assignments of Weather Bureau Army Navy (WBAN) station identifier numbers by the National Climatic Data Center....

SCRAED - Simple and Complex Random Assignment in Experimental Designs

OpenAIRE

Alferes, Valentim R.

2009-01-01

SCRAED is a package of 37 self-contained SPSS syntax files that performs simple and complex random assignment in experimental designs. For between-subjects designs, SCRAED includes simple random assignment (no restrictions, forced equal sizes, forced unequal sizes, and unequal probabilities), block random assignment (simple and generalized blocks), and stratified random assignment (no restrictions, forced equal sizes, forced unequal sizes, and unequal probabilities). For within-subject...

GENERAL ISSUES CONCERNING THE ASSIGNMENT OF SOCIAL PARTS

Directory of Open Access Journals (Sweden)

Stela Mihăilescu

2012-11-01

Full Text Available By means of the present study, we try to offer a thorough image and an analysis concerning the assignment mode of social parts within a company having limited liability. The assignment of social parts is free and unrestricted except for the cases provided by article 202, paragraph 2 from Law no. 31/ 1990- the law of commercial companies with further modifications and completions and the ones provided in OUG no. 54/ 2010 concerning some measures for fighting fiscal evasion. By means of the assignment operation a transmission is made up by an assignment of social parts contract towards one or more already associated persons in the company or towards other individual or legal persons who are going to obtain the associate quality. The principle governing any assignment is the one of goods circulation freedom, a freedom restricted only by the public order and imperative judicial norms.

Stress Assignment in Reading Italian Polysyllabic Pseudowords

Science.gov (United States)

Sulpizio, Simone; Arduino, Lisa S.; Paizi, Despina; Burani, Cristina

2013-01-01

In 4 naming experiments we investigated how Italian readers assign stress to pseudowords. We assessed whether participants assign stress following distributional information such as stress neighborhood (the proportion and number of existent words sharing orthographic ending and stress pattern) and whether such distributional information affects…

Assigning breed origin to alleles in crossbred animals.

Science.gov (United States)

Vandenplas, Jérémie; Calus, Mario P L; Sevillano, Claudia A; Windig, Jack J; Bastiaansen, John W M

2016-08-22

For some species, animal production systems are based on the use of crossbreeding to take advantage of the increased performance of crossbred compared to purebred animals. Effects of single nucleotide polymorphisms (SNPs) may differ between purebred and crossbred animals for several reasons: (1) differences in linkage disequilibrium between SNP alleles and a quantitative trait locus; (2) differences in genetic backgrounds (e.g., dominance and epistatic interactions); and (3) differences in environmental conditions, which result in genotype-by-environment interactions. Thus, SNP effects may be breed-specific, which has led to the development of genomic evaluations for crossbred performance that take such effects into account. However, to estimate breed-specific effects, it is necessary to know breed origin of alleles in crossbred animals. Therefore, our aim was to develop an approach for assigning breed origin to alleles of crossbred animals (termed BOA) without information on pedigree and to study its accuracy by considering various factors, including distance between breeds. The BOA approach consists of: (1) phasing genotypes of purebred and crossbred animals; (2) assigning breed origin to phased haplotypes; and (3) assigning breed origin to alleles of crossbred animals based on a library of assigned haplotypes, the breed composition of crossbred animals, and their SNP genotypes. The accuracy of allele assignments was determined for simulated datasets that include crosses between closely-related, distantly-related and unrelated breeds. Across these scenarios, the percentage of alleles of a crossbred animal that were correctly assigned to their breed origin was greater than 90 %, and increased with increasing distance between breeds, while the percentage of incorrectly assigned alleles was always less than 2 %. For the remaining alleles, i.e. 0 to 10 % of all alleles of a crossbred animal, breed origin could not be assigned. The BOA approach accurately assigns

Support vector machine incremental learning triggered by wrongly predicted samples

Science.gov (United States)

Tang, Ting-long; Guan, Qiu; Wu, Yi-rong

2018-05-01

According to the classic Karush-Kuhn-Tucker (KKT) theorem, at every step of incremental support vector machine (SVM) learning, the newly adding sample which violates the KKT conditions will be a new support vector (SV) and migrate the old samples between SV set and non-support vector (NSV) set, and at the same time the learning model should be updated based on the SVs. However, it is not exactly clear at this moment that which of the old samples would change between SVs and NSVs. Additionally, the learning model will be unnecessarily updated, which will not greatly increase its accuracy but decrease the training speed. Therefore, how to choose the new SVs from old sets during the incremental stages and when to process incremental steps will greatly influence the accuracy and efficiency of incremental SVM learning. In this work, a new algorithm is proposed to select candidate SVs and use the wrongly predicted sample to trigger the incremental processing simultaneously. Experimental results show that the proposed algorithm can achieve good performance with high efficiency, high speed and good accuracy.

Overriding "doing wrong" and "not doing right": validation of the Dispositional Self-Control Scale (DSC).

Science.gov (United States)

Ein-Gar, Danit; Sagiv, Lilach

2014-01-01

We present the Dispositional Self-Control (DSC) Scale, which reflects individuals' tendency to override 2 types of temptations, termed doing wrong and not doing right. We report a series of 5 studies designed to test the reliability and validity of the scale. As hypothesized, high DSC predicts distant future orientation and low DSC predicts deviant behaviors such as aggression, alcohol misuse, and aberrant driving. DSC also predicts task performance among resource-depleted participants. Taken together, these findings suggest that the DSC Scale could be a useful tool toward further understanding the role of personality in overcoming self-control challenges.

Integer Linear Programming for Constrained Multi-Aspect Committee Review Assignment

Science.gov (United States)

Karimzadehgan, Maryam; Zhai, ChengXiang

2011-01-01

Automatic review assignment can significantly improve the productivity of many people such as conference organizers, journal editors and grant administrators. A general setup of the review assignment problem involves assigning a set of reviewers on a committee to a set of documents to be reviewed under the constraint of review quota so that the reviewers assigned to a document can collectively cover multiple topic aspects of the document. No previous work has addressed such a setup of committee review assignments while also considering matching multiple aspects of topics and expertise. In this paper, we tackle the problem of committee review assignment with multi-aspect expertise matching by casting it as an integer linear programming problem. The proposed algorithm can naturally accommodate any probabilistic or deterministic method for modeling multiple aspects to automate committee review assignments. Evaluation using a multi-aspect review assignment test set constructed using ACM SIGIR publications shows that the proposed algorithm is effective and efficient for committee review assignments based on multi-aspect expertise matching. PMID:22711970

26 CFR 301.6503(f)-1 - Suspension of running of period of limitation; wrongful seizure of property of third-party owner...

Science.gov (United States)

2010-04-01

... 26 Internal Revenue 18 2010-04-01 2010-04-01 false Suspension of running of period of limitation... and Collection § 301.6503(f)-1 Suspension of running of period of limitation; wrongful seizure of... running of the period of limitations on collection after assessment prescribed in section 6502 (relating...

Reducing wrong patient selection errors: exploring the design space of user interface techniques.

Science.gov (United States)

Sopan, Awalin; Plaisant, Catherine; Powsner, Seth; Shneiderman, Ben

2014-01-01

Wrong patient selection errors are a major issue for patient safety; from ordering medication to performing surgery, the stakes are high. Widespread adoption of Electronic Health Record (EHR) and Computerized Provider Order Entry (CPOE) systems makes patient selection using a computer screen a frequent task for clinicians. Careful design of the user interface can help mitigate the problem by helping providers recall their patients' identities, accurately select their names, and spot errors before orders are submitted. We propose a catalog of twenty seven distinct user interface techniques, organized according to a task analysis. An associated video demonstrates eighteen of those techniques. EHR designers who consider a wider range of human-computer interaction techniques could reduce selection errors, but verification of efficacy is still needed.

Assignment and Correspondence Tracking System - Tactical / Operational Reporting

Data.gov (United States)

Social Security Administration — Reporting data store for the Assignment and Correspondence Tracking System (ACT). ACT automates the assignment and tracking of correspondence processing within the...

Statistical aspects of optimal treatment assignment

OpenAIRE

van der Linden, Willem J.

1980-01-01

The issues of treatment assignment is ordinarily dealt with within the framework of testing aptitude treatment interaction (ATI) hypothesis. ATI research mostly uses linear regression techniques, and an ATI exists when the aptitude treatment (AT) regression lines cross each other within the relevant interval of the aptitude variable. Consistent with this approach is the use of the points of interaction of AT regression lines as treatment-assignment rule. The replacement of such rules by monot...

One of My Favorite Assignments: Automated Teller Machine Simulation.

Science.gov (United States)

Oberman, Paul S.

2001-01-01

Describes an assignment for an introductory computer science class that requires the student to write a software program that simulates an automated teller machine. Highlights include an algorithm for the assignment; sample file contents; language features used; assignment variations; and discussion points. (LRW)

7 CFR 1900.5 - Assignment of cases.

Science.gov (United States)

2010-01-01

... 7 Agriculture 12 2010-01-01 2010-01-01 false Assignment of cases. 1900.5 Section 1900.5 Agriculture Regulations of the Department of Agriculture (Continued) RURAL HOUSING SERVICE, RURAL BUSINESS... REGULATIONS GENERAL Delegations of Authority § 1900.5 Assignment of cases. The State Director may, in writing...

METHOD FOR SOLVING FUZZY ASSIGNMENT PROBLEM USING MAGNITUDE RANKING TECHNIQUE

OpenAIRE

D. Selvi; R. Queen Mary; G. Velammal

2017-01-01

Assignment problems have various applications in the real world because of their wide applicability in industry, commerce, management science, etc. Traditional classical assignment problems cannot be successfully used for real life problem, hence the use of fuzzy assignment problems is more appropriate. In this paper, the fuzzy assignment problem is formulated to crisp assignment problem using Magnitude Ranking technique and Hungarian method has been applied to find an optimal solution. The N...

A probabilistic approach for validating protein NMR chemical shift assignments

International Nuclear Information System (INIS)

Wang Bowei; Wang, Yunjun; Wishart, David S.

2010-01-01

It has been estimated that more than 20% of the proteins in the BMRB are improperly referenced and that about 1% of all chemical shift assignments are mis-assigned. These statistics also reflect the likelihood that any newly assigned protein will have shift assignment or shift referencing errors. The relatively high frequency of these errors continues to be a concern for the biomolecular NMR community. While several programs do exist to detect and/or correct chemical shift mis-referencing or chemical shift mis-assignments, most can only do one, or the other. The one program (SHIFTCOR) that is capable of handling both chemical shift mis-referencing and mis-assignments, requires the 3D structure coordinates of the target protein. Given that chemical shift mis-assignments and chemical shift re-referencing issues should ideally be addressed prior to 3D structure determination, there is a clear need to develop a structure-independent approach. Here, we present a new structure-independent protocol, which is based on using residue-specific and secondary structure-specific chemical shift distributions calculated over small (3-6 residue) fragments to identify mis-assigned resonances. The method is also able to identify and re-reference mis-referenced chemical shift assignments. Comparisons against existing re-referencing or mis-assignment detection programs show that the method is as good or superior to existing approaches. The protocol described here has been implemented into a freely available Java program called 'Probabilistic Approach for protein Nmr Assignment Validation (PANAV)' and as a web server (http://redpoll.pharmacy.ualberta.ca/PANAVhttp://redpoll.pharmacy.ualberta.ca/PANAV) which can be used to validate and/or correct as well as re-reference assigned protein chemical shifts.

Testing the Effectiveness of Online Assignments in Theory of Finance

Science.gov (United States)

Batu, Michael; Bower, Nancy; Lun, Esmond; Sadanand, Asha

2018-01-01

The authors investigated the effectiveness of online versus paper assignments using final examination scores in three cohorts of theory of finance. In particular, two cohorts were exposed to online assignments while another cohort was exposed to traditional assignments. The central result is that exposure to online assignments robustly leads to…

12 CFR 563e.28 - Assigned ratings.

Science.gov (United States)

2010-01-01

... 12 Banks and Banking 5 2010-01-01 2010-01-01 false Assigned ratings. 563e.28 Section 563e.28 Banks... for Assessing Performance § 563e.28 Assigned ratings. (a) Ratings in general. Subject to paragraphs (b... performance under the lending, investment and service tests, the community development test, the small savings...

Privacy-Preserving Task Assignment in Spatial Crowdsourcing

KAUST Repository

Liu, An

2017-09-20

With the progress of mobile devices and wireless networks, spatial crowdsourcing (SC) is emerging as a promising approach for problem solving. In SC, spatial tasks are assigned to and performed by a set of human workers. To enable effective task assignment, however, both workers and task requesters are required to disclose their locations to untrusted SC systems. In this paper, we study the problem of assigning workers to tasks in a way that location privacy for both workers and task requesters is preserved. We first combine the Paillier cryptosystem with Yao’s garbled circuits to construct a secure protocol that assigns the nearest worker to a task. Considering that this protocol cannot scale to a large number of workers, we then make use of Geohash, a hierarchical spatial index to design a more efficient protocol that can securely find approximate nearest workers. We theoretically show that these two protocols are secure against semi-honest adversaries. Through extensive experiments on two real-world datasets, we demonstrate the efficiency and effectiveness of our protocols.

Incorporating breeding abundance into spatial assignments on continuous surfaces.

Science.gov (United States)

Rushing, Clark S; Marra, Peter P; Studds, Colin E

2017-06-01

Determining the geographic connections between breeding and nonbreeding populations, termed migratory connectivity, is critical to advancing our understanding of the ecology and conservation of migratory species. Assignment models based on stable isotopes historically have been an important tool for studying migratory connectivity of small-bodied species, but the low resolution of these assignments has generated interest into combining isotopes with other sources in information. Abundance is one of the most appealing data sources to include in isotope-based assignments, but there are currently no statistical methods or guidelines for optimizing the contribution of stable isotopes and abundance for inferring migratory connectivity. Using known-origin stable-hydrogen isotope samples of six Neotropical migratory bird species, we rigorously assessed the performance of assignment models that differentially weight the contribution of the isotope and abundance data. For two species with adequate sample sizes, we used Pareto optimality to determine the set of models that simultaneously minimized both assignment error rate and assignment area. We then assessed the ability of the top models from these two species to improve assignments of the remaining four species compared to assignments based on isotopes alone. We show that the increased precision of models that include abundance is often offset by a large increase in assignment error. However, models that optimally weigh the abundance data relative to the isotope data can result in higher precision and, in some cases, lower error than models based on isotopes alone. The top models, however, depended on the distribution of relative breeding abundance, with patchier distributions requiring stronger downweighting of abundance, and we present general guidelines for future studies. These results confirm that breeding abundance can be an important source of information for studies investigating broad-scale movements of

Do Insurers Have to Pay for Bad Behaviour in Settling Claims? Legal Aspects of Insurers' Wrongful Claims Handling

OpenAIRE

Boom, Willem

2011-01-01

textabstractAbstract: This article presents a comparative legal analysis of wrongful claims handling by insurance companies in indemnity and liability insurance. From the outset, it is clear that it may be difficult to draw the line between legitimate claims denial and refusal to pay, on the one hand, and malicious protraction, procrastination and rejection of valid claims, on the other hand. Therefore, it is interesting to find that European legal systems diverge considerably in their stance...

Castor and Pollux - shielded cells for studying fuel treatment processes; Castor et Pollux chaines blindees d'etudes de procedes de traitement de combustibles

Energy Technology Data Exchange (ETDEWEB)

Faudot, G; Bathellier, A [Commissariat a l' Energie Atomique, Fontenay-aux-Roses (France). Centre d' Etudes Nucleaires

1969-07-01

CASTOR and POLLUX, two alpha, beta, gamma cells are described in the present paper. They are located in the CEN at Fontenay-aux-Roses (France). They are designed for improvement studies of the various aqueous separation processes used in irradiated fuels reprocessing plants. Located in the same air-tight steel encasement, they arc inter-connected by a pneumatic transfer. These two cells have a similar in-line conception and they include: a gamma shielding in lead of 10 cm of thickness; an inner air-tight box, made with stainless steel and plexiglas, is maintained in lowering in comparison to room pressure. Eleven Hobson model seven master-slave manipulators allow inner manipulations. Then the inner equipment is described briefly. (author) [French] Le present document decrit les cellules alpha, beta, gamma CASTOR et POLLUX edifiees au Centre d'Etudes Nucleaires de Fontenay-aux-Roses. Elles sont destinees aux etudes visant a l'amelioration des procedes de separation par voie aqueuse utilises dans les usines de retraitement des combustibles irradies. Ces deux chaines, implantees dans le meme caisson et reliees par convoyeur pneumatique, sont de conception identique et comprennent: une protection biologique constituee par 10 cm d'epaisseur de plomb; une enceinte interieure etanche alpha, en acier inoxidable et plexiglas, maintenue en depression. Des telemanipulateurs Hobson, modele 7, permettent les manipulations interieures. On decrit ensuite brievement les installations annexes. (auteur)

Dual earners’ willingness to accept an international assignment.

NARCIS (Netherlands)

van der Velde, E.G.; Bossink, C.J.H.; Jansen, P.G.W.

2005-01-01

Multinational organisations experience difficulties in finding managers willing to accept international assignments. This study has therefore focused on factors that can predict males' and females' willingness to accept international assignments, or to follow their partners on international

Task assignment and coaching

NARCIS (Netherlands)

Dominguez-Martinez, S.

2009-01-01

An important task of a manager is to motivate her subordinates. One way in which a manager can give incentives to junior employees is through the assignment of tasks. How a manager allocates tasks in an organization, provides information to the junior employees about his ability. Without coaching

Supersymmetry with prejudice: Fitting the wrong model to LHC data

Science.gov (United States)

Allanach, B. C.; Dolan, Matthew J.

2012-09-01

We critically examine interpretations of hypothetical supersymmetric LHC signals, fitting to alternative wrong models of supersymmetry breaking. The signals we consider are some of the most constraining on the sparticle spectrum: invariant mass distributions with edges and endpoints from the golden decay chain q˜→qχ20(→l˜±l∓q)→χ10l+l-q. We assume a constrained minimal supersymmetric standard model (CMSSM) point to be the ‘correct’ one, but fit the signals instead with minimal gauge mediated supersymmetry breaking models (mGMSB) with a neutralino quasistable lightest supersymmetric particle, minimal anomaly mediation and large volume string compactification models. Minimal anomaly mediation and large volume scenario can be unambiguously discriminated against the CMSSM for the assumed signal and 1fb-1 of LHC data at s=14TeV. However, mGMSB would not be discriminated on the basis of the kinematic endpoints alone. The best-fit point spectra of mGMSB and CMSSM look remarkably similar, making experimental discrimination at the LHC based on the edges or Higgs properties difficult. However, using rate information for the golden chain should provide the additional separation required.

Calibrated peer review assignments for the earth sciences

Science.gov (United States)

Rudd, J.A.; Wang, V.Z.; Cervato, C.; Ridky, R.W.

2009-01-01

Calibrated Peer Review ??? (CPR), a web-based instructional tool developed as part of the National Science Foundation reform initiatives in undergraduate science education, allows instructors to incorporate multiple writing assignments in large courses without overwhelming the instructor. This study reports successful implementation of CPR in a large, introductory geology course and student learning of geoscience content. For each CPR assignment in this study, students studied web-based and paper resources, wrote an essay, and reviewed seven essays (three from the instructor, three from peers, and their own) on the topic. Although many students expressed negative attitudes and concerns, particularly about the peer review process of this innovative instructional approach, they also recognized the learning potential of completing CPR assignments. Comparing instruction on earthquakes and plate boundaries using a CPR assignment vs. an instructional video lecture and homework essay with extensive instructor feedback, students mastered more content via CPR instruction.

Subcarrier Group Assignment for MC-CDMA Wireless Networks

Directory of Open Access Journals (Sweden)

Le-Ngoc Tho

2007-01-01

Full Text Available Two interference-based subcarrier group assignment strategies in dynamic resource allocation are proposed for MC-CDMA wireless systems to achieve high throughput in a multicell environment. Least interfered group assignment (LIGA selects for each session the subcarrier group on which the user receives the minimum interference, while best channel ratio group assignment (BCRGA chooses the subcarrier group with the largest channel response-to-interference ratio. Both analytical framework and simulation model are developed for evaluation of throughput distribution of the proposed schemes. An iterative approach is devised to handle the complex interdependency between multicell interference profiles in the throughput analysis. Illustrative results show significant throughput improvement offered by the interference-based assignment schemes for MC-CDMA multicell wireless systems. In particular, under low loading conditions, LIGA renders the best performance. However, as the load increases BCRGA tends to offer superior performance.

Subcarrier Group Assignment for MC-CDMA Wireless Networks

Directory of Open Access Journals (Sweden)

Tho Le-Ngoc

2007-12-01

Full Text Available Two interference-based subcarrier group assignment strategies in dynamic resource allocation are proposed for MC-CDMA wireless systems to achieve high throughput in a multicell environment. Least interfered group assignment (LIGA selects for each session the subcarrier group on which the user receives the minimum interference, while best channel ratio group assignment (BCRGA chooses the subcarrier group with the largest channel response-to-interference ratio. Both analytical framework and simulation model are developed for evaluation of throughput distribution of the proposed schemes. An iterative approach is devised to handle the complex interdependency between multicell interference profiles in the throughput analysis. Illustrative results show significant throughput improvement offered by the interference-based assignment schemes for MC-CDMA multicell wireless systems. In particular, under low loading conditions, LIGA renders the best performance. However, as the load increases BCRGA tends to offer superior performance.

RNA-PAIRS: RNA probabilistic assignment of imino resonance shifts

International Nuclear Information System (INIS)

Bahrami, Arash; Clos, Lawrence J.; Markley, John L.; Butcher, Samuel E.; Eghbalnia, Hamid R.

2012-01-01

The significant biological role of RNA has further highlighted the need for improving the accuracy, efficiency and the reach of methods for investigating RNA structure and function. Nuclear magnetic resonance (NMR) spectroscopy is vital to furthering the goals of RNA structural biology because of its distinctive capabilities. However, the dispersion pattern in the NMR spectra of RNA makes automated resonance assignment, a key step in NMR investigation of biomolecules, remarkably challenging. Herein we present RNA Probabilistic Assignment of Imino Resonance Shifts (RNA-PAIRS), a method for the automated assignment of RNA imino resonances with synchronized verification and correction of predicted secondary structure. RNA-PAIRS represents an advance in modeling the assignment paradigm because it seeds the probabilistic network for assignment with experimental NMR data, and predicted RNA secondary structure, simultaneously and from the start. Subsequently, RNA-PAIRS sets in motion a dynamic network that reverberates between predictions and experimental evidence in order to reconcile and rectify resonance assignments and secondary structure information. The procedure is halted when assignments and base-parings are deemed to be most consistent with observed crosspeaks. The current implementation of RNA-PAIRS uses an initial peak list derived from proton-nitrogen heteronuclear multiple quantum correlation ( 1 H– 15 N 2D HMQC) and proton–proton nuclear Overhauser enhancement spectroscopy ( 1 H– 1 H 2D NOESY) experiments. We have evaluated the performance of RNA-PAIRS by using it to analyze NMR datasets from 26 previously studied RNAs, including a 111-nucleotide complex. For moderately sized RNA molecules, and over a range of comparatively complex structural motifs, the average assignment accuracy exceeds 90%, while the average base pair prediction accuracy exceeded 93%. RNA-PAIRS yielded accurate assignments and base pairings consistent with imino resonances for a

RNA-PAIRS: RNA probabilistic assignment of imino resonance shifts

Energy Technology Data Exchange (ETDEWEB)

Bahrami, Arash; Clos, Lawrence J.; Markley, John L.; Butcher, Samuel E. [National Magnetic Resonance Facility at Madison (United States); Eghbalnia, Hamid R., E-mail: eghbalhd@uc.edu [University of Cincinnati, Department of Molecular and Cellular Physiology (United States)

2012-04-15

The significant biological role of RNA has further highlighted the need for improving the accuracy, efficiency and the reach of methods for investigating RNA structure and function. Nuclear magnetic resonance (NMR) spectroscopy is vital to furthering the goals of RNA structural biology because of its distinctive capabilities. However, the dispersion pattern in the NMR spectra of RNA makes automated resonance assignment, a key step in NMR investigation of biomolecules, remarkably challenging. Herein we present RNA Probabilistic Assignment of Imino Resonance Shifts (RNA-PAIRS), a method for the automated assignment of RNA imino resonances with synchronized verification and correction of predicted secondary structure. RNA-PAIRS represents an advance in modeling the assignment paradigm because it seeds the probabilistic network for assignment with experimental NMR data, and predicted RNA secondary structure, simultaneously and from the start. Subsequently, RNA-PAIRS sets in motion a dynamic network that reverberates between predictions and experimental evidence in order to reconcile and rectify resonance assignments and secondary structure information. The procedure is halted when assignments and base-parings are deemed to be most consistent with observed crosspeaks. The current implementation of RNA-PAIRS uses an initial peak list derived from proton-nitrogen heteronuclear multiple quantum correlation ({sup 1}H-{sup 15}N 2D HMQC) and proton-proton nuclear Overhauser enhancement spectroscopy ({sup 1}H-{sup 1}H 2D NOESY) experiments. We have evaluated the performance of RNA-PAIRS by using it to analyze NMR datasets from 26 previously studied RNAs, including a 111-nucleotide complex. For moderately sized RNA molecules, and over a range of comparatively complex structural motifs, the average assignment accuracy exceeds 90%, while the average base pair prediction accuracy exceeded 93%. RNA-PAIRS yielded accurate assignments and base pairings consistent with imino

Interactive visual exploration and refinement of cluster assignments.

Science.gov (United States)

Kern, Michael; Lex, Alexander; Gehlenborg, Nils; Johnson, Chris R

2017-09-12

With ever-increasing amounts of data produced in biology research, scientists are in need of efficient data analysis methods. Cluster analysis, combined with visualization of the results, is one such method that can be used to make sense of large data volumes. At the same time, cluster analysis is known to be imperfect and depends on the choice of algorithms, parameters, and distance measures. Most clustering algorithms don't properly account for ambiguity in the source data, as records are often assigned to discrete clusters, even if an assignment is unclear. While there are metrics and visualization techniques that allow analysts to compare clusterings or to judge cluster quality, there is no comprehensive method that allows analysts to evaluate, compare, and refine cluster assignments based on the source data, derived scores, and contextual data. In this paper, we introduce a method that explicitly visualizes the quality of cluster assignments, allows comparisons of clustering results and enables analysts to manually curate and refine cluster assignments. Our methods are applicable to matrix data clustered with partitional, hierarchical, and fuzzy clustering algorithms. Furthermore, we enable analysts to explore clustering results in context of other data, for example, to observe whether a clustering of genomic data results in a meaningful differentiation in phenotypes. Our methods are integrated into Caleydo StratomeX, a popular, web-based, disease subtype analysis tool. We show in a usage scenario that our approach can reveal ambiguities in cluster assignments and produce improved clusterings that better differentiate genotypes and phenotypes.

Student generated assignments about electrical circuits in a computer simulation

NARCIS (Netherlands)

Vreman-de Olde, Cornelise; de Jong, Anthonius J.M.

2004-01-01

In this study we investigated the design of assignments by students as a knowledge-generating activity. Students were required to design assignments for 'other students' in a computer simulation environment about electrical circuits. Assignments consisted of a question, alternatives, and feedback on

On pole structure assignment in linear systems

Czech Academy of Sciences Publication Activity Database

Loiseau, J.-J.; Zagalak, Petr

2009-01-01

Roč. 82, č. 7 (2009), s. 1179-1192 ISSN 0020-7179 R&D Projects: GA ČR(CZ) GA102/07/1596 Institutional research plan: CEZ:AV0Z10750506 Keywords : linear systems * linear state feedback * pole structure assignment Subject RIV: BC - Control Systems Theory Impact factor: 1.124, year: 2009 http://library.utia.cas.cz/separaty/2009/AS/zagalak-on pole structure assignment in linear systems.pdf

Personnel shift assignment: Existence conditions and network models

NARCIS (Netherlands)

van den Berg, Jeroen P.; van den Berg, J.P.; Panton, David M.

1994-01-01

The personnel scheduling problem is known to be a five-stage process in which the final stage involves the assignment of shifts to the days worked in the schedule. This paper discusses the existence conditions for both continuous and forward rotating shift assignments and heuristic network

75 FR 55355 - Delegation of Authority and Assignment of Responsibility

Science.gov (United States)

2010-09-10

... DEPARTMENT OF LABOR Office of the Secretary Delegation of Authority and Assignment of Responsibility Secretary's Order 4-2010 Subject: Delegation of Authority and Assignment of Responsibility to the... delegations and assignments in full force and effect, except as expressly modified herein. 4. Delegation of...

When Doing Wrong Feels So Right: Normalization of Deviance.

Science.gov (United States)

Price, Mary R; Williams, Teresa C

2018-03-01

Normalization of deviance is a term first coined by sociologist Diane Vaughan when reviewing the Challenger disaster. Vaughan noted that the root cause of the Challenger disaster was related to the repeated choice of NASA officials to fly the space shuttle despite a dangerous design flaw with the O-rings. Vaughan describes this phenomenon as occurring when people within an organization become so insensitive to deviant practice that it no longer feels wrong. Insensitivity occurs insidiously and sometimes over years because disaster does not happen until other critical factors line up. In clinical practice, failing to do time outs before procedures, shutting off alarms, and breaches of infection control are deviances from evidence-based practice. As in other industries, health care workers do not make these choices intending to set into motion a cascade toward disaster and harm. Deviation occurs because of barriers to using the correct process or drivers such as time, cost, and peer pressure. As in other industries, operators will often adamantly defend their actions as necessary and justified. Although many other high-risk industries have embraced the normalization of deviance concept, it is relatively new to health care. It is urgent that we explore the impact of this concept on patient harm. We can borrow this concept from other industries and also the steps these other high-risk organizations have found to prevent it.

Sex Work Criminalization Is Barking Up the Wrong Tree.

Science.gov (United States)

Vanwesenbeeck, Ine

2017-08-01

There is a notable shift toward more repression and criminalization in sex work policies, in Europe and elsewhere. So-called neo-abolitionism reduces sex work to trafficking, with increased policing and persecution as a result. Punitive "demand reduction" strategies are progressively more popular. These developments call for a review of what we know about the effects of punishing and repressive regimes vis-à-vis sex work. From the evidence presented, sex work repression and criminalization are branded as "waterbed politics" that push and shove sex workers around with an overload of controls and regulations that in the end only make things worse. It is illustrated how criminalization and repression make it less likely that commercial sex is worker-controlled, non-abusive, and non-exploitative. Criminalization is seriously at odds with human rights and public health principles. It is concluded that sex work criminalization is barking up the wrong tree because it is fighting sex instead of crime and it is not offering any solution for the structural conditions that sex work (its ugly sides included) is rooted in. Sex work repression travels a dead-end street and holds no promises whatsoever for a better future. To fight poverty and gendered inequalities, the criminal justice system simply is not the right instrument. The reasons for the persistent stigma on sex work as well as for its present revival are considered.

Staff assignment practices in nursing homes: review of the literature.

Science.gov (United States)

Rahman, Anna; Straker, Jane K; Manning, Lydia

2009-01-01

Consistent assignment, whereby nursing home staff members, particularly certified nurse aides, are assigned to the same residents on most shifts, is increasingly viewed as a cornerstone of culture change in nursing homes. It has been advocated as a best-care model that increases residents' quality of life while contributing to a more stable frontline staff. Given these potential benefits, consistent assignment is now widely viewed as superior to rotating assignment, an alternative staffing model that aims to distribute care burden more fairly among staff and ensure that workers are familiar with most residents. Despite favorable anecdotal reports about the benefits of consistent assignment, the research literature reports mixed and sometimes contradictory findings for this staffing practice. This article reviews the research pertaining to staff assignment practices in nursing homes. Reviewed here are 13 reports on experimental trials (6 reports), evaluation research (4 reports), and nursing home surveys (3 reports). The review reveals broad diversity in staffing practices and raises questions that challenge popular assumptions about consistent assignment. The article closes with a discussion of the research, policy, and practice implications of the research findings.

75 FR 55354 - Delegation of Authority and Assignment of Responsibilities

Science.gov (United States)

2010-09-10

... DEPARTMENT OF LABOR Office of the Secretary Delegation of Authority and Assignment of Responsibilities Secretary's Order 3-2010 Subject: Delegation of Authority and Assignment of Responsibilities to... Secretary to enforce sections 18A and 18B of the FLSA. 4. Delegation of Authority and Assignment of...

Quality Control Test for Sequence-Phenotype Assignments

Science.gov (United States)

Ortiz, Maria Teresa Lara; Rosario, Pablo Benjamín Leon; Luna-Nevarez, Pablo; Gamez, Alba Savin; Martínez-del Campo, Ana; Del Rio, Gabriel

2015-01-01

Relating a gene mutation to a phenotype is a common task in different disciplines such as protein biochemistry. In this endeavour, it is common to find false relationships arising from mutations introduced by cells that may be depurated using a phenotypic assay; yet, such phenotypic assays may introduce additional false relationships arising from experimental errors. Here we introduce the use of high-throughput DNA sequencers and statistical analysis aimed to identify incorrect DNA sequence-phenotype assignments and observed that 10–20% of these false assignments are expected in large screenings aimed to identify critical residues for protein function. We further show that this level of incorrect DNA sequence-phenotype assignments may significantly alter our understanding about the structure-function relationship of proteins. We have made available an implementation of our method at http://bis.ifc.unam.mx/en/software/chispas. PMID:25700273

25 CFR 225.33 - Assignment of minerals agreements.

Science.gov (United States)

2010-04-01

... 25 Indians 1 2010-04-01 2010-04-01 false Assignment of minerals agreements. 225.33 Section 225.33 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS OIL AND GAS, GEOTHERMAL, AND SOLID MINERALS AGREEMENTS Minerals Agreements § 225.33 Assignment of minerals agreements. An...

Automating Formative and Summative Feedback for Individualised Assignments

Science.gov (United States)

Hamilton, Ian Robert

2009-01-01

Purpose: The purpose of this paper is to report on the rationale behind the use of a unique paper-based individualised accounting assignment, which automated the provision to students of immediate formative and timely summative feedback. Design/methodology/approach: As students worked towards completing their assignment, the package provided…

submission of art studio-based assignments: students experience

African Journals Online (AJOL)

PUBLICATIONS1

are reluctant to complete their studio assignments on time are critically ... tative and qualitative data, derived from survey and interviews were used to ... is therefore exploratory and studio based. It ... mogenous group of students who report pro- ... Assignment management .... The analyses in this study are based on data.

Heuristic for Task-Worker Assignment with Varying Learning Slopes

Directory of Open Access Journals (Sweden)

Wipawee Tharmmaphornphilas

2010-04-01

Full Text Available Fashion industry has variety products, so the multi-skilled workers are required to improve flexibility in production and assignment. Generally the supervisor will assign task to the workers based on skill and skill levels of worker. Since in fashion industry new product styles are launched more frequently and the order size tends to be smaller, the workers always learn when the raw material and the production process changes. Consequently they require less time to produce the succeeding units of a task based on their learning ability. Since the workers have both experience and inexperience workers, so each worker has different skill level and learning ability. Consequently, the assignment which assumed constant skill level is not proper to use. This paper proposes a task-worker assignment considering worker skill levels and learning abilities. Processing time of each worker changes along production period due to a worker learning ability. We focus on a task-worker assignment in a fashion industry where tasks are ordered in series; the number of tasks is greater than the number of workers. Therefore, workers can perform multiple assignments followed the precedence restriction as an assembly line balancing problem. The problem is formulated in an integer linear programming model with objective to minimize makespan. A heuristic is proposed to determine the lower bound (LB and the upper bound (UB of the problem and the best assignment is determined. The performance of the heuristic method is tested by comparing quality of solution and computational time to optimal solutions.

Assignment Procedures in the Air Force Procurement Management Information System.

Science.gov (United States)

Ward, Joe H., Jr.; And Others

An overview is presented of the procedure for offering jobs in the Air Force Procurement Management Information System (PROMIS), an assignment system which makes possible the use of human resources research findings to improve individual personnel assignments. A general framework for viewing personnel assignment systems is presented; then job…

A property of assignment type mixed integer linear programming problems

NARCIS (Netherlands)

Benders, J.F.; van Nunen, J.A.E.E.

1982-01-01

In this paper we will proof that rather tight upper bounds can be given for the number of non-unique assignments that are achieved after solving the linear programming relaxation of some types of mixed integer linear assignment problems. Since in these cases the number of splitted assignments is

41 CFR 105-8.152 - Program accessibility: Assignment of space.

Science.gov (United States)

2010-07-01

... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Program accessibility: Assignment of space. 105-8.152 Section 105-8.152 Public Contracts and Property Management Federal Property...-8.152 Program accessibility: Assignment of space. (a) When GSA assigns or reassigns space to an...

Scaffolding Assignments and Activities for Undergraduate Research Methods

Science.gov (United States)

Fisher, Sarah; Justwan, Florian

2018-01-01

This article details assignments and lessons created for and tested in research methods courses at two different universities, a large state school and a small liberal arts college. Each assignment or activity utilized scaffolding. Students were asked to push beyond their comfort zone while utilizing concrete and/or creative examples,…

Socially-assigned race, healthcare discrimination and preventive healthcare services.

Directory of Open Access Journals (Sweden)

Tracy Macintosh

Full Text Available Race and ethnicity, typically defined as how individuals self-identify, are complex social constructs. Self-identified racial/ethnic minorities are less likely to receive preventive care and more likely to report healthcare discrimination than self-identified non-Hispanic whites. However, beyond self-identification, these outcomes may vary depending on whether racial/ethnic minorities are perceived by others as being minority or white; this perception is referred to as socially-assigned race.To examine the associations between socially-assigned race and healthcare discrimination and receipt of selected preventive services.Cross-sectional analysis of the 2004 Behavioral Risk Factor Surveillance System "Reactions to Race" module. Respondents from seven states and the District of Columbia were categorized into 3 groups, defined by a composite of self-identified race/socially-assigned race: Minority/Minority (M/M, n = 6,837, Minority/White (M/W, n = 929, and White/White (W/W, n = 25,913. Respondents were 18 years or older, with 61.7% under age 60; 51.8% of respondents were female. Measures included reported healthcare discrimination and receipt of vaccinations and cancer screenings.Racial/ethnic minorities who reported being socially-assigned as minority (M/M were more likely to report healthcare discrimination compared with those who reported being socially-assigned as white (M/W (8.9% vs. 5.0%, p = 0.002. Those reporting being socially-assigned as white (M/W and W/W had similar rates for past-year influenza (73.1% vs. 74.3% and pneumococcal (69.3% vs. 58.6% vaccinations; however, rates were significantly lower among M/M respondents (56.2% and 47.6%, respectively, p-values<0.05. There were no significant differences between the M/M and M/W groups in the receipt of cancer screenings.Racial/ethnic minorities who reported being socially-assigned as white are more likely to receive preventive vaccinations and less likely to report

The Presentation Assignment: Creating Learning Opportunities for Diverse Student Populations.

Science.gov (United States)

Spencer, Brenda H.; Bartle-Angus, Kathryn

2000-01-01

Finds the presentation assignment to be an effective method of providing students with the opportunity to apply the literacy skills they are learning in ways that are personally meaningful. Describes the presentation assignment framework and provides an example of an assignment that required students to analyze and interpret works of literature…

Triage level assignment and nurse characteristics and experience.

Science.gov (United States)

Gómez-Angelats, Elisenda; Miró, Òscar; Bragulat Baur, Ernesto; Antolín Santaliestra, Alberto; Sánchez Sánchez, Miquel

2018-06-01

To study the relation between nursing staff demographics and experience and their assignment of triage level in the emergency department. One-year retrospective observational study in the triage area of a tertiary care urban university hospital that applies the Andorran-Spanish triage model. Variables studied were age, gender, nursing experience, triage experience, shift, usual level of emergency work the nurse undertakes, number of triage decisions made, and percentage of patients assigned to each level. Fifty nurses (5 men, 45 women) with a mean (SD) age of 45 (9) years triaged 67 803 patients during the year. Nurses classified more patients in level 5 on the morning shift (7.9%) than on the afternoon shift (5.5%) (P=.003). The difference in the rate of level-5 triage classification became significant when nurses were older (β = 0.092, P=.037) and experience was greater (β = 0.103, P=.017). The number of triages recorded by a nurse was significantly and directly related to the percentage of patients assigned to level 3 (β = 0.003, P=.006) and inversely related to the percentages assigned to level 4 (β = -0.002, P=.008) and level 5 (β = -0.001, P=.017). We found that triage level assignments were related to age, experience, shift, and total number of patients triaged by a nurse.

Visual words assignment via information-theoretic manifold embedding.

Science.gov (United States)

Deng, Yue; Li, Yipeng; Qian, Yanjun; Ji, Xiangyang; Dai, Qionghai

2014-10-01

Codebook-based learning provides a flexible way to extract the contents of an image in a data-driven manner for visual recognition. One central task in such frameworks is codeword assignment, which allocates local image descriptors to the most similar codewords in the dictionary to generate histogram for categorization. Nevertheless, existing assignment approaches, e.g., nearest neighbors strategy (hard assignment) and Gaussian similarity (soft assignment), suffer from two problems: 1) too strong Euclidean assumption and 2) neglecting the label information of the local descriptors. To address the aforementioned two challenges, we propose a graph assignment method with maximal mutual information (GAMI) regularization. GAMI takes the power of manifold structure to better reveal the relationship of massive number of local features by nonlinear graph metric. Meanwhile, the mutual information of descriptor-label pairs is ultimately optimized in the embedding space for the sake of enhancing the discriminant property of the selected codewords. According to such objective, two optimization models, i.e., inexact-GAMI and exact-GAMI, are respectively proposed in this paper. The inexact model can be efficiently solved with a closed-from solution. The stricter exact-GAMI nonparametrically estimates the entropy of descriptor-label pairs in the embedding space and thus leads to a relatively complicated but still trackable optimization. The effectiveness of GAMI models are verified on both the public and our own datasets.

Contact replacement for NMR resonance assignment.

Science.gov (United States)

Xiong, Fei; Pandurangan, Gopal; Bailey-Kellogg, Chris

2008-07-01

Complementing its traditional role in structural studies of proteins, nuclear magnetic resonance (NMR) spectroscopy is playing an increasingly important role in functional studies. NMR dynamics experiments characterize motions involved in target recognition, ligand binding, etc., while NMR chemical shift perturbation experiments identify and localize protein-protein and protein-ligand interactions. The key bottleneck in these studies is to determine the backbone resonance assignment, which allows spectral peaks to be mapped to specific atoms. This article develops a novel approach to address that bottleneck, exploiting an available X-ray structure or homology model to assign the entire backbone from a set of relatively fast and cheap NMR experiments. We formulate contact replacement for resonance assignment as the problem of computing correspondences between a contact graph representing the structure and an NMR graph representing the data; the NMR graph is a significantly corrupted, ambiguous version of the contact graph. We first show that by combining connectivity and amino acid type information, and exploiting the random structure of the noise, one can provably determine unique correspondences in polynomial time with high probability, even in the presence of significant noise (a constant number of noisy edges per vertex). We then detail an efficient randomized algorithm and show that, over a variety of experimental and synthetic datasets, it is robust to typical levels of structural variation (1-2 AA), noise (250-600%) and missings (10-40%). Our algorithm achieves very good overall assignment accuracy, above 80% in alpha-helices, 70% in beta-sheets and 60% in loop regions. Our contact replacement algorithm is implemented in platform-independent Python code. The software can be freely obtained for academic use by request from the authors.

28 CFR 545.23 - Inmate work/program assignment.

Science.gov (United States)

2010-07-01

... community living area, unless the pretrial inmate has signed a waiver of his or her right not to work (see... 28 Judicial Administration 2 2010-07-01 2010-07-01 false Inmate work/program assignment. 545.23... WORK AND COMPENSATION Inmate Work and Performance Pay Program § 545.23 Inmate work/program assignment...

Optimal assignment of incoming flights to baggage carousels at airports

DEFF Research Database (Denmark)

Barth, Torben C.

The problem considered in this report is an assignment problem occurring at airports. This problem concerns the assignment of baggage carousels in baggage claim halls to arriving aircraft (baggage carousel assignment problem). This is a highly dynamic problem since disruptions frequently occur du...... and in general is a substantial support in decision making....

PARETO OPTIMAL SOLUTIONS FOR MULTI-OBJECTIVE GENERALIZED ASSIGNMENT PROBLEM

Directory of Open Access Journals (Sweden)

S. Prakash

2012-01-01

Full Text Available

ENGLISH ABSTRACT: The Multi-Objective Generalized Assignment Problem (MGAP with two objectives, where one objective is linear and the other one is non-linear, has been considered, with the constraints that a job is assigned to only one worker – though he may be assigned more than one job, depending upon the time available to him. An algorithm is proposed to find the set of Pareto optimal solutions of the problem, determining assignments of jobs to workers with two objectives without setting priorities for them. The two objectives are to minimise the total cost of the assignment and to reduce the time taken to complete all the jobs.

AFRIKAANSE OPSOMMING: ‘n Multi-doelwit veralgemeende toekenningsprobleem (“multi-objective generalised assignment problem – MGAP” met twee doelwitte, waar die een lineêr en die ander nielineêr is nie, word bestudeer, met die randvoorwaarde dat ‘n taak slegs toegedeel word aan een werker – alhoewel meer as een taak aan hom toegedeel kan word sou die tyd beskikbaar wees. ‘n Algoritme word voorgestel om die stel Pareto-optimale oplossings te vind wat die taaktoedelings aan werkers onderhewig aan die twee doelwitte doen sonder dat prioriteite toegeken word. Die twee doelwitte is om die totale koste van die opdrag te minimiseer en om die tyd te verminder om al die take te voltooi.

Game theory and traffic assignment.

Science.gov (United States)

2013-09-01

Traffic assignment is used to determine the number of users on roadway links in a network. While this problem has : been widely studied in transportation literature, its use of the concept of equilibrium has attracted considerable interest : in the f...

Simulated annealing algorithm for solving chambering student-case assignment problem

Science.gov (United States)

Ghazali, Saadiah; Abdul-Rahman, Syariza

2015-12-01

The problem related to project assignment problem is one of popular practical problem that appear nowadays. The challenge of solving the problem raise whenever the complexity related to preferences, the existence of real-world constraints and problem size increased. This study focuses on solving a chambering student-case assignment problem by using a simulated annealing algorithm where this problem is classified under project assignment problem. The project assignment problem is considered as hard combinatorial optimization problem and solving it using a metaheuristic approach is an advantage because it could return a good solution in a reasonable time. The problem of assigning chambering students to cases has never been addressed in the literature before. For the proposed problem, it is essential for law graduates to peruse in chambers before they are qualified to become legal counselor. Thus, assigning the chambering students to cases is a critically needed especially when involving many preferences. Hence, this study presents a preliminary study of the proposed project assignment problem. The objective of the study is to minimize the total completion time for all students in solving the given cases. This study employed a minimum cost greedy heuristic in order to construct a feasible initial solution. The search then is preceded with a simulated annealing algorithm for further improvement of solution quality. The analysis of the obtained result has shown that the proposed simulated annealing algorithm has greatly improved the solution constructed by the minimum cost greedy heuristic. Hence, this research has demonstrated the advantages of solving project assignment problem by using metaheuristic techniques.

The analysis of possibility of physical rehabilitation at pelvic presentation and wrong positions of a fetus during pregnancy.

Directory of Open Access Journals (Sweden)

Brega L.B.

2011-04-01

Full Text Available It is considered the main reasons of occurrence and correction possibility by rehabilitation means of wrong positions and pelvic presentation a fetus during pregnancy. It is resulted the analysis of publications in which modern possibilities of influence on correction of a pathological condition by means of application of means of physical rehabilitation are shined. It is established the importance of early revealing, correction and fetus fixing in head prelying prior to the beginning of patrimonial activity, feature of carrying out corrective training at pregnant women.

Efficient Mechanisms to Allocate Assignment Incentives in the Navy

National Research Council Canada - National Science Library

Nimon, R. W; Hall, Ricky D; Zaki, Hossam

2005-01-01

.... All assignments, however, may not necessarily be voluntary. These assignments (jobs) have been labeled as "hard to fill" by Navy leadership, and the Navy has implemented market-based, cash stipends to attract Sailors to these jobs...

Ant Colony Algorithm and Simulation for Robust Airport Gate Assignment

Directory of Open Access Journals (Sweden)

Hui Zhao

2014-01-01

Full Text Available Airport gate assignment is core task for airport ground operations. Due to the fact that the departure and arrival time of flights may be influenced by many random factors, the airport gate assignment scheme may encounter gate conflict and many other problems. This paper aims at finding a robust solution for airport gate assignment problem. A mixed integer model is proposed to formulate the problem, and colony algorithm is designed to solve this model. Simulation result shows that, in consideration of robustness, the ability of antidisturbance for airport gate assignment scheme has much improved.

Assigning agents to a line

DEFF Research Database (Denmark)

Hougaard, Jens Leth; Moreno-Ternero, Juan D.; Østerdal, Lars Peter Raahave

2014-01-01

minimizing modification of the classic random priority method to solve this class of problems. We also provide some logical relations in our setting among standard axioms in the literature on assignment problems, and explore the robustness of our results to several extensions of our setting....

The ICAP (Interactive Course Assignment Pages Publishing System

Directory of Open Access Journals (Sweden)

Kim Griggs

2008-03-01

Full Text Available The ICAP publishing system is an open source custom content management system that enables librarians to easily and quickly create and manage library help pages for course assignments (ICAPs, without requiring knowledge of HTML or other web technologies. The system's unique features include an emphasis on collaboration and content reuse and an easy-to-use interface that includes in-line help, simple forms and drag and drop functionality. The system generates dynamic, attractive course assignment pages that blend Web 2.0 features with traditional library resources, and makes the pages easier to find by providing a central web page for the course assignment pages. As of December 2007, the code is available as free, open-source software under the GNU General Public License.

A fatal and unusual iatrogenic fourth right lumbar artery injury complicating wrong-level hemilaminectomy: a case report and literature review.

Science.gov (United States)

Ventura, Francesco; Barranco, Rosario; Bernabei, Carlo; Castelletti, Lara; Castellan, Lucio

2017-07-07

The authors describe an unusual case of a fatal iatrogenic fourth lumbar artery injury during left hemilaminectomy in a 38-year-old woman. At autopsy, gross inspection revealed hemoperitoneum with 1,800 ml of free blood and massive retroperitoneal extravasation. A laceration with irregular and jagged margins was detected on the wall of the fourth right lumbar artery. The autopsy and the post-mortem TC investigations demonstrated that wrong-level hemilaminectomy was performed for the herniated disc.

Covariance NMR Processing and Analysis for Protein Assignment.

Science.gov (United States)

Harden, Bradley J; Frueh, Dominique P

2018-01-01

During NMR resonance assignment it is often necessary to relate nuclei to one another indirectly, through their common correlations to other nuclei. Covariance NMR has emerged as a powerful technique to correlate such nuclei without relying on error-prone peak peaking. However, false-positive artifacts in covariance spectra have impeded a general application to proteins. We recently introduced pre- and postprocessing steps to reduce the prevalence of artifacts in covariance spectra, allowing for the calculation of a variety of 4D covariance maps obtained from diverse combinations of pairs of 3D spectra, and we have employed them to assign backbone and sidechain resonances in two large and challenging proteins. In this chapter, we present a detailed protocol describing how to (1) properly prepare existing 3D spectra for covariance, (2) understand and apply our processing script, and (3) navigate and interpret the resulting 4D spectra. We also provide solutions to a number of errors that may occur when using our script, and we offer practical advice when assigning difficult signals. We believe such 4D spectra, and covariance NMR in general, can play an integral role in the assignment of NMR signals.

Genetics of traffic assignment models for strategic transport planning

NARCIS (Netherlands)

Bliemer, M.C.J.; Raadsen, M.P.H.; Brederode, L.J.N.; Bell, M.G.H.; Wismans, Luc Johannes Josephus; Smith, M.J.

2016-01-01

This paper presents a review and classification of traffic assignment models for strategic transport planning purposes by using concepts analogous to genetics in biology. Traffic assignment models share the same theoretical framework (DNA), but differ in capability (genes). We argue that all traffic

Designing Internet research assignments: building a framework for instructor collaboration

Directory of Open Access Journals (Sweden)

David Ward

2000-01-01

Full Text Available Internet knowledge is increasing steadily among instructors in the academic world. As courses incorporate more instructional technology, traditional undergraduate research assignments are adapting to reflect the changing world of information and information access. New library assignments reflect this shift as well, with term papers and research projects asking students to use Web sites as an information resource, in addition to the standard literature of periodicals and monographs. But the many pitfalls the library profession has learned in its own metamorphosis during the past decade are often repeated in these newer course assignments. The authors in this paper present a framework for librarians to interact with instructors to incorporate Internet resources into traditional term paper and research assignments. They suggest a framework for creating sample assignments librarians can take to campus instructional units, to show the teaching community at large what the library profession has learned from first-hand experience.

Questioning the foundations of physics which of our fundamental assumptions are wrong?

CERN Document Server

Foster, Brendan; Merali, Zeeya

2015-01-01

The essays in this book look at way in which the fundaments of physics might need to be changed in order to make progress towards a unified theory. They are based on the prize-winning essays submitted to the FQXi essay competition “Which of Our Basic Physical Assumptions Are Wrong?”, which drew over 270 entries. As Nobel Laureate physicist Philip W. Anderson realized, the key to understanding nature’s reality is not anything “magical”, but the right attitude, “the focus on asking the right questions, the willingness to try (and to discard) unconventional answers, the sensitive ear for phoniness, self-deception, bombast, and conventional but unproven assumptions.” The authors of the eighteen prize-winning essays have, where necessary, adapted their essays for the present volume so as to (a) incorporate the community feedback generated in the online discussion of the essays, (b) add new material that has come to light since their completion and (c) to ensure accessibility to a broad audience of re...

Postgraduate diploma collaborative assignment: Implications for ...

African Journals Online (AJOL)

Postgraduate diploma collaborative assignment: Implications for ESL students ... and collaborative teaching/learning model involving the major course convenors. ... The quality of the work and mood of all concerned improved tremendously.

Automated backbone assignment of labeled proteins using the threshold accepting algorithm

International Nuclear Information System (INIS)

Leutner, Michael; Gschwind, Ruth M.; Liermann, Jens; Schwarz, Christian; Gemmecker, Gerd; Kessler, Horst

1998-01-01

The sequential assignment of backbone resonances is the first step in the structure determination of proteins by heteronuclear NMR. For larger proteins, an assignment strategy based on proton side-chain information is no longer suitable for the use in an automated procedure. Our program PASTA (Protein ASsignment by Threshold Accepting) is therefore designed to partially or fully automate the sequential assignment of proteins, based on the analysis of NMR backbone resonances plus C β information. In order to overcome the problems caused by peak overlap and missing signals in an automated assignment process, PASTA uses threshold accepting, a combinatorial optimization strategy, which is superior to simulated annealing due to generally faster convergence and better solutions. The reliability of this algorithm is shown by reproducing the complete sequential backbone assignment of several proteins from published NMR data. The robustness of the algorithm against misassigned signals, noise, spectral overlap and missing peaks is shown by repeating the assignment with reduced sequential information and increased chemical shift tolerances. The performance of the program on real data is finally demonstrated with automatically picked peak lists of human nonpancreatic synovial phospholipase A 2 , a protein with 124 residues

Assigning spectra of chaotic molecules with diabatic correlation diagrams

International Nuclear Information System (INIS)

Rose, J.P.; Kellman, M.E.

1996-01-01

An approach for classifying and organizing spectra of highly excited vibrational states of molecules is investigated. As a specific example, we analyze the spectrum of an effective spectroscopic fitting Hamiltonian for H 2 O. In highly excited spectra, multiple resonance couplings and anharmonicity interact to give branching of the N original normal modes into new anharmonic modes, accompanied by the onset of widespread chaos. The anharmonic modes are identified by means of a bifurcation analysis of the spectroscopic Hamiltonian. A diabatic correlation diagram technique is developed to assign the levels with approximate open-quote open-quote dynamical close-quote close-quote quantum numbers corresponding to the dynamics determined from the bifurcation analysis. The resulting assignment shows significant disturbance from the conventional spectral pattern organization into sequences and progressions. The open-quote open-quote dynamical close-quote close-quote assignment is then converted into an assignment in terms of open-quote open-quote nominal close-quote close-quote quantum numbers that function like the N normal mode quantum numbers at low energy. The nominal assignments are used to reconstruct, as much as possible, an organization of the spectrum resembling the usual separation into sequences and progressions. copyright 1996 American Institute of Physics

Parentage assignment of progeny in mixed milt fertilization of ...

African Journals Online (AJOL)

Administrator

2011-06-13

Jun 13, 2011 ... individuals. Overall, 98.8% of progeny were assigned to their parents using Family Assignment. Program (FAP). Selection of hyper-variable microsatellites in Caspian brown trout to identify unique alleles was effective for unambiguous parentage determination and estimation of genetic diversity in this study.

Integrating Academic Journal Review Assignments into a Graduate Business Leadership Course

Science.gov (United States)

Schultz, Jennifer L.; Agrimonti, Lisa M.; Higbee, Jeanne L.

2016-01-01

Graduate course assignments that are pragmatic, challenging, scaffold prior learning, and support academic career aspirations can be difficult to create and even more problematic to assess for even the most experienced faculty. This paper presents a class assignment that incorporated a real-world journal reviewing assignment into an elective…

20 CFR 422.104 - Who can be assigned a social security number.

Science.gov (United States)

2010-04-01

... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Who can be assigned a social security number... General Procedures § 422.104 Who can be assigned a social security number. (a) Persons eligible for SSN assignment. We can assign you a social security number if you meet the evidence requirements in § 422.107 and...

32 CFR 644.396 - Assignment of personnel to administer.

Science.gov (United States)

2010-07-01

... 32 National Defense 4 2010-07-01 2010-07-01 true Assignment of personnel to administer. 644.396... PROPERTY REAL ESTATE HANDBOOK Disposal Predisposal Action § 644.396 Assignment of personnel to administer... responsible representative to each installation, or group of installations, to act under his staff supervision...

A Poster Assignment Connects Information Literacy and Writing Skills

Science.gov (United States)

Waters, Natalie

2015-01-01

This paper describes the implementation of a poster assignment in a writing and information literacy course required for undergraduate Life Sciences and Environmental Biology majors with the Faculty of Agricultural and Environmental Sciences at McGill University. The assignment was introduced in response to weaknesses identified through course…

Is something wrong with the second pillar in Switzerland?: Gender inequalities from a perspective of two Private Occupational Pension Institutions

OpenAIRE

Kucera, Jacqueline; Suter, Christian; Halford, Susan; Crettaz, Eric

2015-01-01

Inequalities and old age pension systems have been analyzed in depth by many scholars. This study tackles the question of gender inequalities in a propaedeutic manner and asks: “Is something wrong with the second pillar in Switzerland?” By perceiving the occupational pension system as secure and safe, the focus of this thesis lies in the idea of guaranteeing equality for future pensions. The thesis asks whether gender inequalities occur through the mechanism of interpretation of the Federal L...

42 CFR 421.114 - Assignment and reassignment of providers by CMS.

Science.gov (United States)

2010-10-01

... 42 Public Health 3 2010-10-01 2010-10-01 false Assignment and reassignment of providers by CMS. 421.114 Section 421.114 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH... Assignment and reassignment of providers by CMS. CMS may assign or reassign any provider to any intermediary...

28 CFR 0.153 - Selection and assignment of employees for training.

Science.gov (United States)

2010-07-01

... 28 Judicial Administration 1 2010-07-01 2010-07-01 false Selection and assignment of employees for... Selection and assignment of employees for training. The Director of the Federal Bureau of Investigation, the....S.C. 4109, with respect to the selection and assignment of employees for training by, in, or through...

26 CFR 1.401(a)-13 - Assignment or alienation of benefits.

Science.gov (United States)

2010-04-01

... 26 Internal Revenue 5 2010-04-01 2010-04-01 false Assignment or alienation of benefits. 1.401(a...)-13 Assignment or alienation of benefits. (a) Scope of the regulations. This section applies only to..., provided for employer contributions. (b) No assignment or alienation—(1) General rule. Under section 401(a...

5 CFR 839.621 - Can I cancel my FERS election if I was in the wrong retirement plan at the time I elected FERS...

Science.gov (United States)

2010-01-01

... 5 Administrative Personnel 2 2010-01-01 2010-01-01 false Can I cancel my FERS election if I was in the wrong retirement plan at the time I elected FERS coverage and I have an election opportunity under... ERRONEOUS RETIREMENT COVERAGE CORRECTIONS ACT Making an Election Fers Elections § 839.621 Can I cancel my...

Measurement of the Wrong-Sign Decays D0→K+π-π0 and D0→K+π-π+π-, and Search for CP Violation

International Nuclear Information System (INIS)

Tian, X.C.; Ban, Y.; Ying, J.; Abe, K.; Gershon, T.; Haba, J.; Hazumi, M.; Ishikawa, A.; Itoh, R.; Iwasaki, Y.; Katayama, N.; Kichimi, H.; Nakazawa, H.; Nishida, S.; Ozaki, H.; Sakai, Y.; Takasaki, F.; Tamai, K.; Tanaka, M.; Tsukamoto, T.

2005-01-01

Using 281 fb -1 of data from the Belle experiment recorded at or near the Υ(4S) resonance, we have measured the rates of the ''wrong-sign'' decays D 0 →K + π - π 0 and D 0 →K + π - π + π - relative to those of the Cabibbo-favored decays D 0 →K - π + π 0 and D 0 →K - π + π + π - . These wrong-sign decays proceed via a doubly Cabibbo-suppressed amplitude or via D 0 -D 0 mixing; the latter has not yet been observed. We obtain R WS (Kππ 0 )=[0.229±0.015(stat) -0.009 +0.013 (syst)]% and R WS (K3π)=[0.320±0.018(stat) -0.013 +0.018 (syst)]%. The CP asymmetries are measured to be -0.006±0.053 and -0.018±0.044 for the K + π - π 0 and K + π - π + π - final states, respectively

Elof Risebye – A Pioneer in the Transfer of Wall Paintings on the Wrong Path

DEFF Research Database (Denmark)

Brajer, Isabelle Eve

2001-01-01

The transfer of wall paintings was introduced to Denmark by Italian restorers in 1913. A misunderstanding of this technique led to the development of a faulty method by Elof Risebye, an artist, who by chance got involved in the restoration of wall paintings. The use of the wrong adhesive resulted...... in massive damage of the paint layer. Risebye disguised his losses by overpainting, which he carried out according to his own style of painting, not at all following the style of the painter's whose work he was restoring. He also taught his students at the Fresco and Mosaic School how to detach frescoes......, thus disseminating his faulty method. Due to Risebye's activities there are a significant number of transferred wall paintings in Denmark which are in dire need of treatment today....

DNATCO: assignment of DNA conformers at dnatco.org.

Science.gov (United States)

Černý, Jiří; Božíková, Paulína; Schneider, Bohdan

2016-07-08

The web service DNATCO (dnatco.org) classifies local conformations of DNA molecules beyond their traditional sorting to A, B and Z DNA forms. DNATCO provides an interface to robust algorithms assigning conformation classes called NTC: to dinucleotides extracted from DNA-containing structures uploaded in PDB format version 3.1 or above. The assigned dinucleotide NTC: classes are further grouped into DNA structural alphabet NTA: , to the best of our knowledge the first DNA structural alphabet. The results are presented at two levels: in the form of user friendly visualization and analysis of the assignment, and in the form of a downloadable, more detailed table for further analysis offline. The website is free and open to all users and there is no login requirement. © The Author(s) 2016. Published by Oxford University Press on behalf of Nucleic Acids Research.

Effective Homework Assignments. Research Brief

Science.gov (United States)

Cooper, Harris

2008-01-01

Perhaps more than any question other than "How much time should students spend doing homework?" parents and educators want to know, "What kinds of homework assignments are most effective?" Clearly, the answers to this question vary according to many factors, especially the developmental level of students and the topic area. Generally, answers are…

Dynamic traffic assignment : genetic algorithms approach

Science.gov (United States)

1997-01-01

Real-time route guidance is a promising approach to alleviating congestion on the nations highways. A dynamic traffic assignment model is central to the development of guidance strategies. The artificial intelligence technique of genetic algorithm...

On some special cases of the restricted assignment problem

NARCIS (Netherlands)

Wang, C. (Chao); R.A. Sitters (René)

2016-01-01

textabstractWe consider some special cases of the restricted assignment problem. In this scheduling problem on parallel machines, any job j can only be assigned to one of the machines in its given subset Mj of machines. We give an LP-formulation for the problem with two job sizes and show that it

13 CFR 500.210 - Assignment or transfer of loans.

Science.gov (United States)

2010-01-01

... has the effect of distributing the risks of the credit among other Lenders if: (i) Neither the loan... be modified, assigned, conveyed, sold or otherwise transferred by the Lender, in whole or in part... assignment or transfer of less than 100 percent of a Lender's interest in the Loan Documents and Guarantee...

A parametric visualization software for the assignment problem

Directory of Open Access Journals (Sweden)

Papamanthou Charalampos

2005-01-01

Full Text Available In this paper we present a parametric visualization software used to assist the teaching of the Network Primal Simplex Algorithm for the assignment problem (AP. The assignment problem is a special case of the balanced transportation problem. The main functions of the algorithm and design techniques are also presented. Through this process, we aim to underline the importance and necessity of using such educational methods in order to improve the teaching of Computer Algorithms.

The Utility of Writing Assignments in Undergraduate Bioscience

Science.gov (United States)

Libarkin, Julie; Ording, Gabriel

2012-01-01

We tested the hypothesis that engagement in a few, brief writing assignments in a nonmajors science course can improve student ability to convey critical thought about science. A sample of three papers written by students (n = 30) was coded for presence and accuracy of elements related to scientific writing. Scores for different aspects of scientific writing were significantly correlated, suggesting that students recognized relationships between components of scientific thought. We found that students' ability to write about science topics and state conclusions based on data improved over the course of three writing assignments, while the abilities to state a hypothesis and draw clear connections between human activities and environmental impacts did not improve. Three writing assignments generated significant change in student ability to write scientifically, although our results suggest that three is an insufficient number to generate complete development of scientific writing skills. PMID:22383616

A search asymmetry reversed by figure-ground assignment.

Science.gov (United States)

Humphreys, G W; Müller, H

2000-05-01

We report evidence demonstrating that a search asymmetry favoring concave over convex targets can be reversed by altering the figure-ground assignment of edges in shapes. Visual search for a concave target among convex distractors is faster than search for a convex target among concave distractors (a search asymmetry). By using shapes with ambiguous local figure-ground relations, we demonstrated that search can be efficient (with search slopes around 10 ms/item) or inefficient (with search slopes around 30-40 ms/item) with the same stimuli, depending on whether edges are assigned to concave or convex "figures." This assignment process can operate in a top-down manner, according to the task set. The results suggest that attention is allocated to spatial regions following the computation of figure-ground relations in parallel across the elements present. This computation can also be modulated by top-down processes.

A Bayesian approach to estimating hidden variables as well as missing and wrong molecular interactions in ordinary differential equation-based mathematical models.

Science.gov (United States)

Engelhardt, Benjamin; Kschischo, Maik; Fröhlich, Holger

2017-06-01

Ordinary differential equations (ODEs) are a popular approach to quantitatively model molecular networks based on biological knowledge. However, such knowledge is typically restricted. Wrongly modelled biological mechanisms as well as relevant external influence factors that are not included into the model are likely to manifest in major discrepancies between model predictions and experimental data. Finding the exact reasons for such observed discrepancies can be quite challenging in practice. In order to address this issue, we suggest a Bayesian approach to estimate hidden influences in ODE-based models. The method can distinguish between exogenous and endogenous hidden influences. Thus, we can detect wrongly specified as well as missed molecular interactions in the model. We demonstrate the performance of our Bayesian dynamic elastic-net with several ordinary differential equation models from the literature, such as human JAK-STAT signalling, information processing at the erythropoietin receptor, isomerization of liquid α -Pinene, G protein cycling in yeast and UV-B triggered signalling in plants. Moreover, we investigate a set of commonly known network motifs and a gene-regulatory network. Altogether our method supports the modeller in an algorithmic manner to identify possible sources of errors in ODE-based models on the basis of experimental data. © 2017 The Author(s).

Interactive Level Design for iOS Assignment Delivery: A Case Study

Directory of Open Access Journals (Sweden)

Anson Brown

2014-02-01

Full Text Available This paper presents an application of an iOS-based online gaming assignment in a real classroom. The core concept of the project is a gameplay environment involving two players that have full control over creation and modification of levels. This level design mechanism was implemented in an iOS-based game in the area of genetics and based on an existing written assignment. The game includes support for both instructors, who have the ability to create and post assignments and students, who can take the assignments. Two trials of the iOS application consisted of in-class testing of twenty- one students. Students first took the original paper assignment, followed by the iOS version. Start times, end times, and grades were recorded for both versions. A comprehensive study of the grades and times for the iOS version of the assignment versus the paper version was conducted and is presented in this paper. Our Study showed that the iOS version was completed much faster in nearly every case while a strong delivery mechanism is needed to ensure student grades and completion of the assignment will not be affected. These results are not unexpected due to some major difference between the two formats. Future updates and additions will address any currently existing issues.

14 CFR 1245.109 - Assignment of title to NASA.

Science.gov (United States)

2010-01-01

... 14 Aeronautics and Space 5 2010-01-01 2010-01-01 false Assignment of title to NASA. 1245.109... INTELLECTUAL PROPERTY RIGHTS Patent Waiver Regulations § 1245.109 Assignment of title to NASA. (a) The instrument of waiver set forth in § 1245.115(c) shall be voided by NASA with respect to the domestic title to...

Cue competition affects temporal dynamics of edge-assignment in human visual cortex.

Science.gov (United States)

Brooks, Joseph L; Palmer, Stephen E

2011-03-01

Edge-assignment determines the perception of relative depth across an edge and the shape of the closer side. Many cues determine edge-assignment, but relatively little is known about the neural mechanisms involved in combining these cues. Here, we manipulated extremal edge and attention cues to bias edge-assignment such that these two cues either cooperated or competed. To index their neural representations, we flickered figure and ground regions at different frequencies and measured the corresponding steady-state visual-evoked potentials (SSVEPs). Figural regions had stronger SSVEP responses than ground regions, independent of whether they were attended or unattended. In addition, competition and cooperation between the two edge-assignment cues significantly affected the temporal dynamics of edge-assignment processes. The figural SSVEP response peaked earlier when the cues causing it cooperated than when they competed, but sustained edge-assignment effects were equivalent for cooperating and competing cues, consistent with a winner-take-all outcome. These results provide physiological evidence that figure-ground organization involves competitive processes that can affect the latency of figural assignment.

Task assignment and coaching

OpenAIRE

Dominguez-Martinez, S.

2009-01-01

An important task of a manager is to motivate her subordinates. One way in which a manager can give incentives to junior employees is through the assignment of tasks. How a manager allocates tasks in an organization, provides information to the junior employees about his ability. Without coaching from a manager, the junior employee only has information about his past performance. Based on his past performance, a talented junior who has performed a difficult task sometimes decides to leave the...

Implementing a cornerstone of culture change: Consistent staff assignment in VHA community living centers.

Science.gov (United States)

Lemke, Sonne; Brennan, Penny L; SooHoo, Sonya; Schutte, Kathleen K

2017-08-01

In 2011, the Veterans Health Administration (VHA) began implementing consistent staff assignment in its nursing homes (called Community Living Centers or CLCs). Consistent assignment, a cornerstone of culture change, minimizes the number of staff who provide a resident's care. The present research assessed the level and stability of consistent assignment in units within VHA CLCs and identified unit characteristics related to implementation of this staff assignment model. Schedulers in 185 of 335 organizational units that make up VHA CLCs completed a Staffing Practices Survey. For the month prior to the survey, 53% of CLC units had full implementation of consistent assignment. Tracked back over time, 37% of CLC units had stable high consistent assignment, 29% had stable low consistent assignment, and 34% were variable. Units with stable high consistent assignment were most likely to use care teams with stable membership and to obtain staff input for care assignments. Schedulers in these units reported more positive experiences with consistent staff assignment and better unit functioning in terms of staff absences, complaints about workload fairness, and resolution of scheduling problems. Units with stable low and variable consistent assignment were similar in most of these respects; however, units with variable consistent assignment made greater use of stable care teams and were less likely to change assignments at a staff member's request. Overall, consistent assignment implementation was not related to unit size, nursing hours per resident day, or specialty focus. Findings can help guide consistent staff assignment implementation in VHA and community nursing homes. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

The impact of taxation on international assignment decisions: A principal-agent approach

OpenAIRE

Martini, Jan Thomas; Niemann, Rainer

2013-01-01

In many industries like management consulting, IT consulting, or construction highly qualified employees, i.e., experts or executive managers, have to be assigned to temporary projects. In firms with many employees and various different projects, this assignment decision involves a complex optimization procedure. Obviously, the employees’ productivities in the respective projects are crucial for the employer’s optimal assignment decision, but assignment can also be affected by risk-incent...

Automated Bug Assignment: Ensemble-based Machine Learning in Large Scale Industrial Contexts

OpenAIRE

Jonsson, Leif; Borg, Markus; Broman, David; Sandahl, Kristian; Eldh, Sigrid; Runeson, Per

2016-01-01

Bug report assignment is an important part of software maintenance. In particular, incorrect assignments of bug reports to development teams can be very expensive in large software development projects. Several studies propose automating bug assignment techniques using machine learning in open source software contexts, but no study exists for large-scale proprietary projects in industry. The goal of this study is to evaluate automated bug assignment techniques that are based on machine learni...

The Errors of Individualistic Public Health Interventions: Denial of Treatment to Obese Persons; Comment on “Denial of Treatment to Obese Patients—the Wrong Policy on Personal Responsibility for Health”

Directory of Open Access Journals (Sweden)

Daniel S. Goldberg

2013-01-01

Full Text Available I agree entirely with Nir Eyal’s perspective that denying treatment to obese patients is morally wrong. However, the reasons for this belief differ in some ways from Eyal’s analysis. In this commentary, I will try to explain the similarities and differences in our perspectives. My primary claim is that the denial of treatment to obese patients is wrong principally because (i it eschews a whole-population approach to the problem of poor nutrition and is therefore likely to be ineffective; (ii it is likely to expand obesity-related health inequities; and (iii it is likely to intensify stigma against already-marginalized social groups. I shall consider each in turn, and explore the extent to which Eyal would be likely to agree with my claims.

Contribution to the study of the production and properties of finely divided solids, prepared in a flame reactor (1960); Contribution a l'etude de procedes d'obtention et des proprietes des solides finement divises elabores dans un reacteur a flamme (1960)

Energy Technology Data Exchange (ETDEWEB)

Cuer, J P [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

1960-04-15

Sufficiently fine particles cannot be obtained by the grinding of crystals. It is therefore logical to adopt a method whereby the solid is formed from a compound in the vapour phase notable amongst such compounds, volatile at moderate temperatures, are certain organic derivatives of metals and the metallic halides. Formation of the solid from its gaseous derivative should be possible by hydrolysis or oxidation without the dispersion of the reaction medium being modified. The simplest method seems to be to obtain the reaction in an oxy-hydrogen blow-pipe. When the gases in the blow-pipe contain a volatile metallic compound, precipitation of finely divided solid in the form of oxide is produced in the flame at high temperature. Aluminium, titanium, iron and zirconium oxides and silica, the particles of which are spherical and very homogeneous in diameter, have been prepared in this way. The specific surfaces calculated from the diameters on electron microscope photographs are in agreement with those measured by adsorption of nitrogen at 195 deg. C. The oxides thus prepared are therefore not intensely porous. The properties and size of the oxide particles are studied as a function of various operational parameters, such as flame temperature and concentration of volatile metal derivative in the reactive gases. When the blow-pipe is supplied with oxide particles of small diameter, a very marked increase in size is observed. The properties of these preparations are also examined. (author) [French] Les procedes de broyage des cristaux ne conduisent pas a des particules suffisamment fines. Aussi, il est logique de s'adresser a un procede de formation du solide a partir d'un compose se trouvant en phase vapeur. De tels composes, volatils a des temperatures moderees, sont notamment certains derives organiques des metaux et les halogenures metalliques. La formation du solide a partir de son derive gazeux doit pouvoir etre effectuee par l'hydrolyse ou l'oxydation, sans que la

An integer programming model for gate assignment problem at airline terminals

Science.gov (United States)

Chun, Chong Kok; Nordin, Syarifah Zyurina

2015-05-01

In this paper, we concentrate on a gate assignment problem (GAP) at the airlines terminal. Our problem is to assign an arrival plane to a suitable gate. There are two considerations needed to take. One of its is passenger walking distance from arrival gate to departure gate while another consideration is the transport baggage distance from one gate to another. Our objective is to minimize the total distance between the gates that related to assign the arrival plane to the suitable gates. An integer linear programming (ILP) model is proposed to solve this gate assignment problem. We also conduct a computational experiment using CPLEX 12.1 solver in AIMMS 3.10 software to analyze the performance of the model. Results of the computational experiments are presented. The efficiency of flights assignment is depends on the ratio of the weight for both total passenger traveling distances and total baggage transport distances.

Automated solid-state NMR resonance assignment of protein microcrystals and amyloids

Energy Technology Data Exchange (ETDEWEB)

Schmidt, Elena [Goethe University Frankfurt am Main, Center for Biomolecular Magnetic Resonance, Institute of Biophysical Chemistry (Germany); Gath, Julia [ETH Zurich, Physical Chemistry (Switzerland); Habenstein, Birgit [UMR 5086 CNRS/Universite de Lyon 1, Institut de Biologie et Chimie des Proteines (France); Ravotti, Francesco; Szekely, Kathrin; Huber, Matthias [ETH Zurich, Physical Chemistry (Switzerland); Buchner, Lena [Goethe University Frankfurt am Main, Center for Biomolecular Magnetic Resonance, Institute of Biophysical Chemistry (Germany); Boeckmann, Anja, E-mail: a.bockmann@ibcp.fr [UMR 5086 CNRS/Universite de Lyon 1, Institut de Biologie et Chimie des Proteines (France); Meier, Beat H., E-mail: beme@ethz.ch [ETH Zurich, Physical Chemistry (Switzerland); Guentert, Peter, E-mail: guentert@em.uni-frankfurt.de [Goethe University Frankfurt am Main, Center for Biomolecular Magnetic Resonance, Institute of Biophysical Chemistry (Germany)

2013-07-15

Solid-state NMR is an emerging structure determination technique for crystalline and non-crystalline protein assemblies, e.g., amyloids. Resonance assignment constitutes the first and often very time-consuming step to a structure. We present ssFLYA, a generally applicable algorithm for automatic assignment of protein solid-state NMR spectra. Application to microcrystals of ubiquitin and the Ure2 prion C-terminal domain, as well as amyloids of HET-s(218-289) and {alpha}-synuclein yielded 88-97 % correctness for the backbone and side-chain assignments that are classified as self-consistent by the algorithm, and 77-90 % correctness if also assignments classified as tentative by the algorithm are included.

Web-Based Problem-Solving Assignment and Grading System

Science.gov (United States)

Brereton, Giles; Rosenberg, Ronald

2014-11-01

In engineering courses with very specific learning objectives, such as fluid mechanics and thermodynamics, it is conventional to reinforce concepts and principles with problem-solving assignments and to measure success in problem solving as an indicator of student achievement. While the modern-day ease of copying and searching for online solutions can undermine the value of traditional assignments, web-based technologies also provide opportunities to generate individualized well-posed problems with an infinite number of different combinations of initial/final/boundary conditions, so that the probability of any two students being assigned identical problems in a course is vanishingly small. Such problems can be designed and programmed to be: single or multiple-step, self-grading, allow students single or multiple attempts; provide feedback when incorrect; selectable according to difficulty; incorporated within gaming packages; etc. In this talk, we discuss the use of a homework/exam generating program of this kind in a single-semester course, within a web-based client-server system that ensures secure operation.

Lower region: a new cue for figure-ground assignment.

Science.gov (United States)

Vecera, Shaun P; Vogel, Edward K; Woodman, Geoffrey F

2002-06-01

Figure-ground assignment is an important visual process; humans recognize, attend to, and act on figures, not backgrounds. There are many visual cues for figure-ground assignment. A new cue to figure-ground assignment, called lower region, is presented: Regions in the lower portion of a stimulus array appear more figurelike than regions in the upper portion of the display. This phenomenon was explored, and it was demonstrated that the lower-region preference is not influenced by contrast, eye movements, or voluntary spatial attention. It was found that the lower region is defined relative to the stimulus display, linking the lower-region preference to pictorial depth perception cues. The results are discussed in terms of the environmental regularities that this new figure-ground cue may reflect.

The impact of paralogy on phylogenomic studies - a case study on annelid relationships.

Directory of Open Access Journals (Sweden)

Torsten H Struck

Full Text Available Phylogenomic studies based on hundreds of genes derived from expressed sequence tags libraries are increasingly used to reveal the phylogeny of taxa. A prerequisite for these studies is the assignment of genes into clusters of orthologous sequences. Sophisticated methods of orthology prediction are used in such analyses, but it is rarely assessed whether paralogous sequences have been erroneously grouped together as orthologous sequences after the prediction, and whether this had an impact on the phylogenetic reconstruction using a super-matrix approach. Herein, I tested the impact of paralogous sequences on the reconstruction of annelid relationships based on phylogenomic datasets. Using single-partition analyses, screening for bootstrap support, blast searches and pruning of sequences in the supermatrix, wrongly assigned paralogous sequences were found in eight partitions and the placement of five taxa (the annelids Owenia, Scoloplos, Sthenelais and Eurythoe and the nemertean Cerebratulus including the robust bootstrap support could be attributed to the presence of paralogous sequences in two partitions. Excluding these sequences resulted in a different, weaker supported placement for these taxa. Moreover, the analyses revealed that paralogous sequences impacted the reconstruction when only a single taxon represented a previously supported higher taxon such as a polychaete family. One possibility of a priori detection of wrongly assigned paralogous sequences could combine 1 a screening of single-partition analyses based on criteria such as nodal support or internal branch length with 2 blast searches of suspicious cases as presented herein. Also possible are a posteriori approaches in which support for specific clades is investigated by comparing alternative hypotheses based on differences in per-site likelihoods. Increasing the sizes of EST libraries will also decrease the likelihood of wrongly assigned paralogous sequences, and in the case

75 FR 55352 - Delegation of Authorities and Assignment of Responsibilities

Science.gov (United States)

2010-09-10

... DEPARTMENT OF LABOR Office of the Secretary Delegation of Authorities and Assignment of Responsibilities Secretary's Order 5-2010 Subject: Delegation of Authorities and Assignment of Responsibilities to... rather than the Administrator, WHD (see also Secretary's Order 3-2010). 5. Delegations of Authority and...

Smartnotebook: A semi-automated approach to protein sequential NMR resonance assignments

International Nuclear Information System (INIS)

Slupsky, Carolyn M.; Boyko, Robert F.; Booth, Valerie K.; Sykes, Brian D.

2003-01-01

Complete and accurate NMR spectral assignment is a prerequisite for high-throughput automated structure determination of biological macromolecules. However, completely automated assignment procedures generally encounter difficulties for all but the most ideal data sets. Sources of these problems include difficulty in resolving correlations in crowded spectral regions, as well as complications arising from dynamics, such as weak or missing peaks, or atoms exhibiting more than one peak due to exchange phenomena. Smartnotebook is a semi-automated assignment software package designed to combine the best features of the automated and manual approaches. The software finds and displays potential connections between residues, while the spectroscopist makes decisions on which connection is correct, allowing rapid and robust assignment. In addition, smartnotebook helps the user fit chains of connected residues to the primary sequence of the protein by comparing the experimentally determined chemical shifts with expected shifts derived from a chemical shift database, while providing bookkeeping throughout the assignment procedure

ZAP: a distributed channel assignment algorithm for cognitive radio networks

Directory of Open Access Journals (Sweden)

Munaretto Anelise

2011-01-01

Full Text Available Abstract We propose ZAP, an algorithm for the distributed channel assignment in cognitive radio (CR networks. CRs are capable of identifying underutilized licensed bands of the spectrum, allowing their reuse by secondary users without interfering with primary users. In this context, efficient channel assignment is challenging as ideally it must be simple, incur acceptable communication overhead, provide timely response, and be adaptive to accommodate frequent changes in the network. Another challenge is the optimization of network capacity through interference minimization. In contrast to related work, ZAP addresses these challenges with a fully distributed approach based only on local (neighborhood knowledge, while significantly reducing computational costs and the number of messages required for channel assignment. Simulations confirm the efficiency of ZAP in terms of (i the performance tradeoff between different metrics and (ii the fast achievement of a suitable assignment solution regardless of network size and density.

Strategy-Proof Assignment Of Multiple Resources

DEFF Research Database (Denmark)

Erlanson, Albin; Szwagrzak, Karol

2015-01-01

We examine the strategy-proof allocation of multiple resources; an application is the assignment of packages of tasks, workloads, and compensations among the members of an organization. In the domain of multidimensional single-peaked preferences, we find that any allocation mechanism obtained by ...

Statistical aspects of optimal treatment assignment

NARCIS (Netherlands)

van der Linden, Willem J.

The issues of treatment assignment is ordinarily dealt with within the framework of testing aptitude treatment interaction (ATI) hypothesis. ATI research mostly uses linear regression techniques, and an ATI exists when the aptitude treatment (AT) regression lines cross each other within the relevant

Privacy-Preserving Task Assignment in Spatial Crowdsourcing

KAUST Repository

Liu, An; Li, Zhi-Xu; Liu, Guan-Feng; Zheng, Kai; Zhang, Min; Li, Qing; Zhang, Xiangliang

2017-01-01

untrusted SC systems. In this paper, we study the problem of assigning workers to tasks in a way that location privacy for both workers and task requesters is preserved. We first combine the Paillier cryptosystem with Yao’s garbled circuits to construct a secure protocol that assigns the nearest worker to a task. Considering that this protocol cannot scale to a large number of workers, we then make use of Geohash, a hierarchical spatial index to design a more efficient protocol that can securely find approximate nearest workers. We theoretically show that these two protocols are secure against semi-honest adversaries. Through extensive experiments on two real-world datasets, we demonstrate the efficiency and effectiveness of our protocols.

Automated solid-state NMR resonance assignment of protein microcrystals and amyloids

International Nuclear Information System (INIS)

Schmidt, Elena; Gath, Julia; Habenstein, Birgit; Ravotti, Francesco; Székely, Kathrin; Huber, Matthias; Buchner, Lena; Böckmann, Anja; Meier, Beat H.; Güntert, Peter

2013-01-01

Solid-state NMR is an emerging structure determination technique for crystalline and non-crystalline protein assemblies, e.g., amyloids. Resonance assignment constitutes the first and often very time-consuming step to a structure. We present ssFLYA, a generally applicable algorithm for automatic assignment of protein solid-state NMR spectra. Application to microcrystals of ubiquitin and the Ure2 prion C-terminal domain, as well as amyloids of HET-s(218–289) and α-synuclein yielded 88–97 % correctness for the backbone and side-chain assignments that are classified as self-consistent by the algorithm, and 77–90 % correctness if also assignments classified as tentative by the algorithm are included

At least some errors are randomly generated (Freud was wrong)

Science.gov (United States)

Sellen, A. J.; Senders, J. W.

1986-01-01

An experiment was carried out to expose something about human error generating mechanisms. In the context of the experiment, an error was made when a subject pressed the wrong key on a computer keyboard or pressed no key at all in the time allotted. These might be considered, respectively, errors of substitution and errors of omission. Each of seven subjects saw a sequence of three digital numbers, made an easily learned binary judgement about each, and was to press the appropriate one of two keys. Each session consisted of 1,000 presentations of randomly permuted, fixed numbers broken into 10 blocks of 100. One of two keys should have been pressed within one second of the onset of each stimulus. These data were subjected to statistical analyses in order to probe the nature of the error generating mechanisms. Goodness of fit tests for a Poisson distribution for the number of errors per 50 trial interval and for an exponential distribution of the length of the intervals between errors were carried out. There is evidence for an endogenous mechanism that may best be described as a random error generator. Furthermore, an item analysis of the number of errors produced per stimulus suggests the existence of a second mechanism operating on task driven factors producing exogenous errors. Some errors, at least, are the result of constant probability generating mechanisms with error rate idiosyncratically determined for each subject.

A feedback model of figure-ground assignment.

Science.gov (United States)

Domijan, Drazen; Setić, Mia

2008-05-30

A computational model is proposed in order to explain how bottom-up and top-down signals are combined into a unified perception of figure and background. The model is based on the interaction between the ventral and the dorsal stream. The dorsal stream computes saliency based on boundary signals provided by the simple and the complex cortical cells. Output from the dorsal stream is projected to the surface network which serves as a blackboard on which the surface representation is formed. The surface network is a recurrent network which segregates different surfaces by assigning different firing rates to them. The figure is labeled by the maximal firing rate. Computer simulations showed that the model correctly assigns figural status to the surface with a smaller size, a greater contrast, convexity, surroundedness, horizontal-vertical orientation and a higher spatial frequency content. The simple gradient of activity in the dorsal stream enables the simulation of the new principles of the lower region and the top-bottom polarity. The model also explains how the exogenous attention and the endogenous attention may reverse the figural assignment. Due to the local excitation in the surface network, neural activity at the cued region will spread over the whole surface representation. Therefore, the model implements the object-based attentional selection.

AN EVOLUTIONARY ALGORITHM FOR CHANNEL ASSIGNMENT PROBLEM IN WIRELESS MOBILE NETWORKS

Directory of Open Access Journals (Sweden)

Yee Shin Chia

2012-12-01

Full Text Available The channel assignment problem in wireless mobile network is the assignment of appropriate frequency spectrum to incoming calls while maintaining a satisfactory level of electromagnetic compatibility (EMC constraints. An effective channel assignment strategy is important due to the limited capacity of frequency spectrum in wireless mobile network. Most of the existing channel assignment strategies are based on deterministic methods. In this paper, an adaptive genetic algorithm (GA based channel assignment strategy is introduced for resource management and to reduce the effect of EMC interferences. The most significant advantage of the proposed optimization method is its capability to handle both the reassignment of channels for existing calls as well as the allocation of channel to a new incoming call in an adaptive process to maximize the utility of the limited resources. It is capable to adapt the population size to the number of eligible channels for a particular cell upon new call arrivals to achieve reasonable convergence speed. The MATLAB simulation on a 49-cells network model for both uniform and nonuniform call traffic distributions showed that the proposed channel optimization method can always achieve a lower average new incoming call blocking probability compared to the deterministic based channel assignment strategy.

The "Outsider/Insider" Assignment: A Pedagogical Innovation for Teaching Cross-Cultural Understanding

Science.gov (United States)

Garcia, Angela Cora

2014-01-01

In this paper, I describe an innovative assignment for teaching undergraduate students cross-cultural understanding. The Outsider/Insider assignment simultaneously teaches facts about cultural difference and skills for managing cross-cultural encounters. Briefly, the assignment is to write two short papers, one in which the student describes a…

Moving beyond "Bookish Knowledge": Using Film-Based Assignments to Promote Deep Learning

Science.gov (United States)

Olson, Joann S.; Autry, Linda; Moe, Jeffry

2016-01-01

This article investigates the effectiveness of a film-based assignment given to adult learners in a graduate-level group counseling class. Semi-structured interviews were conducted with four students; data analysis suggested film-based assignments may promote deep approaches to learning (DALs). Participants indicated the assignment helped them…

Tabu search for target-radar assignment

DEFF Research Database (Denmark)

Hindsberger, Magnus; Vidal, Rene Victor Valqui

2000-01-01

In the paper the problem of assigning air-defense illumination radars to enemy targets is presented. A tabu search metaheuristic solution is described and the results achieved are compared to those of other heuristic approaches, implementation and experimental aspects are discussed. It is argued ...

Semi-infinite assignment and transportation games

NARCIS (Netherlands)

Timmer, Judith B.; Sánchez-Soriano, Joaqu´ın; Llorca, Navidad; Tijs, Stef; Goberna, Miguel A.; López, Marco A.

2001-01-01

Games corresponding to semi-infinite transportation and related assignment situations are studied. In a semi-infinite transportation situation, one aims at maximizing the profit from the transportation of a certain good from a finite number of suppliers to an infinite number of demanders. An

Single machine scheduling with slack due dates assignment

Science.gov (United States)

Liu, Weiguo; Hu, Xiangpei; Wang, Xuyin

2017-04-01

This paper considers a single machine scheduling problem in which each job is assigned an individual due date based on a common flow allowance (i.e. all jobs have slack due date). The goal is to find a sequence for jobs, together with a due date assignment, that minimizes a non-regular criterion comprising the total weighted absolute lateness value and common flow allowance cost, where the weight is a position-dependent weight. In order to solve this problem, an ? time algorithm is proposed. Some extensions of the problem are also shown.

The Bankers’ New Clothes – What’s Wrong with Banking and What to Do about It

Directory of Open Access Journals (Sweden)

Fernando Moreira

2017-05-01

Full Text Available Sometimes inaccurate arguments are repeated so often and with impressive (apparent authority that most people take them for granted. Anat Admati and Martin Hellwig illustrate one of these situations in their book The Bankers’ New Clothes: What’s Wrong with Banking and What to Do about It. By using a pun inspired by the classic tale The Emperor’s New Clothes by Hans Andersen, Admati and Hellwig guide us around the world of the “bankers’ new clothes”, that is,  “flawed and misleading claims that are made in discussions about banking regulation” (p. 9. In the tale, everybody initially pretends to see the emperor’s invisible clothes in order not to appear stupid given that the invisible clothes were made by two (allegedly highly skilled weavers.   

Stoplight Grid: a color-coded visual system for per diem staff assignment.

Science.gov (United States)

Ernst, P

1989-02-01

What is the best way to appropriately assign per diem nursing personnel? The author describes a systematic approach to per diem staff assignment called the Stoplight Grid. The Stoplight Grid correlates staff skills and preferences with unit needs and integrates this data into a color-coded system for staff assignment.

30 CFR 285.408 - May I assign my lease or grant interest?

Science.gov (United States)

2010-07-01

... RENEWABLE ENERGY ALTERNATE USES OF EXISTING FACILITIES ON THE OUTER CONTINENTAL SHELF Lease and Grant... application to MMS. The assignment application must include: (1) The MMS-assigned lease or grant number; (2) A... required financial assurance. (c) If you submit an application to assign a lease or grant, you will...

7 CFR 929.150 - Transfer or assignment of sales history.

Science.gov (United States)

2010-01-01

... 7 Agriculture 8 2010-01-01 2010-01-01 false Transfer or assignment of sales history. 929.150... MARKETING SERVICE (Marketing Agreements and Orders; Fruits, Vegetables, Nuts), DEPARTMENT OF AGRICULTURE... Transfer or assignment of sales history. (a) If indebtedness is incurred with regard to the acreage to...

Assigning Main Orientation to an EOH Descriptor on Multispectral Images.

Science.gov (United States)

Li, Yong; Shi, Xiang; Wei, Lijun; Zou, Junwei; Chen, Fang

2015-07-01

This paper proposes an approach to compute an EOH (edge-oriented histogram) descriptor with main orientation. EOH has a better matching ability than SIFT (scale-invariant feature transform) on multispectral images, but does not assign a main orientation to keypoints. Alternatively, it tends to assign the same main orientation to every keypoint, e.g., zero degrees. This limits EOH to matching keypoints between images of translation misalignment only. Observing this limitation, we propose assigning to keypoints the main orientation that is computed with PIIFD (partial intensity invariant feature descriptor). In the proposed method, SIFT keypoints are detected from images as the extrema of difference of Gaussians, and every keypoint is assigned to the main orientation computed with PIIFD. Then, EOH is computed for every keypoint with respect to its main orientation. In addition, an implementation variant is proposed for fast computation of the EOH descriptor. Experimental results show that the proposed approach performs more robustly than the original EOH on image pairs that have a rotation misalignment.

PARAssign-paramagnetic NMR assignments of protein nuclei on the basis of pseudocontact shifts

Energy Technology Data Exchange (ETDEWEB)

Skinner, Simon P., E-mail: skinnersp@chem.leidenuniv.nl [Leiden University, Gorlaeus Laboratories, Leiden Institute of Chemistry (Netherlands); Moshev, Mois, E-mail: mois@monomon.me [Leiden University, Leiden Institute of Advanced Computer Science (Netherlands); Hass, Mathias A. S., E-mail: hassmas@chem.leidenuniv.nl; Ubbink, Marcellus, E-mail: m.ubbink@chem.leidenuniv.nl [Leiden University, Gorlaeus Laboratories, Leiden Institute of Chemistry (Netherlands)

2013-04-15

The use of paramagnetic NMR data for the refinement of structures of proteins and protein complexes is widespread. However, the power of paramagnetism for protein assignment has not yet been fully exploited. PARAssign is software that uses pseudocontact shift data derived from several paramagnetic centers attached to the protein to obtain amide and methyl assignments. The ability of PARAssign to perform assignment when the positions of the paramagnetic centers are known and unknown is demonstrated. PARAssign has been tested using synthetic data for methyl assignment of a 47 kDa protein, and using both synthetic and experimental data for amide assignment of a 14 kDa protein. The complex fitting space involved in such an assignment procedure necessitates that good starting conditions are found, both regarding placement and strength of paramagnetic centers. These starting conditions are obtained through automated tensor placement and user-defined tensor parameters. The results presented herein demonstrate that PARAssign is able to successfully perform resonance assignment in large systems with a high degree of reliability. This software provides a method for obtaining the assignments of large systems, which may previously have been unassignable, by using 2D NMR spectral data and a known protein structure.

LOW POWER RACE-FREE STATE ASSIGNMENT OF AN ASYNGHRONOUS AUTOMATON

Directory of Open Access Journals (Sweden)

Yu. V. Pottosin

2015-01-01

Full Text Available The problem of a race free state assignment of an asynchronous automaton is considered. A method for the state assignment is suggested that provides the minimization of the number and theswitching activity of the memory elements along with the elimination of the critical races betweenthem.

Capacity constrained assignment in spatial databases

DEFF Research Database (Denmark)

U, Leong Hou; Yiu, Man Lung; Mouratidis, Kyriakos

2008-01-01

large to fit in main memory. Motivated by this fact, we propose efficient algorithms for optimal assignment that employ novel edge-pruning strategies, based on the spatial properties of the problem. Additionally, we develop approximate (i.e., suboptimal) CCA solutions that provide a trade-off between...

A Method Based on Dial's Algorithm for Multi-time Dynamic Traffic Assignment

Directory of Open Access Journals (Sweden)

Rongjie Kuang

2014-03-01

Full Text Available Due to static traffic assignment has poor performance in reflecting actual case and dynamic traffic assignment may incurs excessive compute cost, method of multi-time dynamic traffic assignment combining static and dynamic traffic assignment balances factors of precision and cost effectively. A method based on Dial's logit algorithm is proposed in the article to solve the dynamic stochastic user equilibrium problem in dynamic traffic assignment. Before that, a fitting function that can proximately reflect overloaded traffic condition of link is proposed and used to give corresponding model. Numerical example is given to illustrate heuristic procedure of method and to compare results with one of same example solved by other literature's algorithm. Results show that method based on Dial's algorithm is preferable to algorithm from others.

Effectiveness of author-assigned keywords to INIS indexing

International Nuclear Information System (INIS)

Yokoo, Hiroshi; Takahashi, Satoko; Habara, Tadashi

1977-01-01

A test was carried out on the quality of indexing data which is based only upon author-assigned keywords in order to appreciate effectiveness of the keywords. As measures of the quality, the retrievability and the consistency of the indexing data were evaluated by comparison with the case of the conventional indexing method under the circumstances of the INIS descriptor assignment to the journal articles of the Atomic Energy Society of Japan. The indexing consistency obtained was approximately 0.61 on an average (or 0.66 when the narrower-broader hierarchical relations were regarded as consistent ones). Of the hit, noise, or total documents retrieved with the conventional indexing data, 0.86, 0.27, or 0.71, respectively, were retrievable with the keywords-based indexing data. From the results the recall ratio for the keywords-based indexing is estimated to be no less than 0.86 of that for the conventional indexing method, and the consistency of the hit documents are to be 0.75 at least. Consequently, the author-assigned keywords proved to be very effective to the document indexing. (auth.)

Automated sequence-specific protein NMR assignment using the memetic algorithm MATCH

International Nuclear Information System (INIS)

Volk, Jochen; Herrmann, Torsten; Wuethrich, Kurt

2008-01-01

MATCH (Memetic Algorithm and Combinatorial Optimization Heuristics) is a new memetic algorithm for automated sequence-specific polypeptide backbone NMR assignment of proteins. MATCH employs local optimization for tracing partial sequence-specific assignments within a global, population-based search environment, where the simultaneous application of local and global optimization heuristics guarantees high efficiency and robustness. MATCH thus makes combined use of the two predominant concepts in use for automated NMR assignment of proteins. Dynamic transition and inherent mutation are new techniques that enable automatic adaptation to variable quality of the experimental input data. The concept of dynamic transition is incorporated in all major building blocks of the algorithm, where it enables switching between local and global optimization heuristics at any time during the assignment process. Inherent mutation restricts the intrinsically required randomness of the evolutionary algorithm to those regions of the conformation space that are compatible with the experimental input data. Using intact and artificially deteriorated APSY-NMR input data of proteins, MATCH performed sequence-specific resonance assignment with high efficiency and robustness

A code reviewer assignment model incorporating the competence differences and participant preferences

Directory of Open Access Journals (Sweden)

Wang Yanqing

2016-03-01

Full Text Available A good assignment of code reviewers can effectively utilize the intellectual resources, assure code quality and improve programmers’ skills in software development. However, little research on reviewer assignment of code review has been found. In this study, a code reviewer assignment model is created based on participants’ preference to reviewing assignment. With a constraint of the smallest size of a review group, the model is optimized to maximize review outcomes and avoid the negative impact of “mutual admiration society”. This study shows that the reviewer assignment strategies incorporating either the reviewers’ preferences or the authors’ preferences get much improvement than a random assignment. The strategy incorporating authors’ preference makes higher improvement than that incorporating reviewers’ preference. However, when the reviewers’ and authors’ preference matrixes are merged, the improvement becomes moderate. The study indicates that the majority of the participants have a strong wish to work with reviewers and authors having highest competence. If we want to satisfy the preference of both reviewers and authors at the same time, the overall improvement of learning outcomes may be not the best.

Automatic Assignment of Methyl-NMR Spectra of Supramolecular Machines Using Graph Theory.

Science.gov (United States)

Pritišanac, Iva; Degiacomi, Matteo T; Alderson, T Reid; Carneiro, Marta G; Ab, Eiso; Siegal, Gregg; Baldwin, Andrew J

2017-07-19

Methyl groups are powerful probes for the analysis of structure, dynamics and function of supramolecular assemblies, using both solution- and solid-state NMR. Widespread application of the methodology has been limited due to the challenges associated with assigning spectral resonances to specific locations within a biomolecule. Here, we present Methyl Assignment by Graph Matching (MAGMA), for the automatic assignment of methyl resonances. A graph matching protocol examines all possibilities for each resonance in order to determine an exact assignment that includes a complete description of any ambiguity. MAGMA gives 100% accuracy in confident assignments when tested against both synthetic data, and 9 cross-validated examples using both solution- and solid-state NMR data. We show that this remarkable accuracy enables a user to distinguish between alternative protein structures. In a drug discovery application on HSP90, we show the method can rapidly and efficiently distinguish between possible ligand binding modes. By providing an exact and robust solution to methyl resonance assignment, MAGMA can facilitate significantly accelerated studies of supramolecular machines using methyl-based NMR spectroscopy.

Anomalous origin of the coronary artery from the wrong coronary sinus evaluated with computed tomography: ''High-risk'' anatomy and its clinical relevance

International Nuclear Information System (INIS)

Krupinski, Maciej; Urbanczyk-Zawadzka, Malgorzata; Laskowicz, Bartosz; Irzyk, Malgorzata; Banys, Robert; Klimeczek, Piotr; Gruszczynska, Katarzyna; Baron, Jan

2014-01-01

The aim of the study was to assess coronary arteries arising from the wrong coronary sinus, including CT-evaluated high-risk anatomic features, clinical symptoms and cardiac events during follow-up. A total of 7,115 patients scheduled for 64-slice or dual-source cardiac CT were screened for the presence of isolated anomalous origin of the coronary artery from the wrong coronary sinus. Anomalous origin of the coronary artery was found in 54 (0.76 %) patients (29 men, 25 women, mean age 60.9 ± 11.6 years). Sixteen (30 %) patients with abnormal right coronary origin (ARCA) more commonly had a slit-like orifice (15 vs. 3; p < 0.001), intramural course (15 vs. 3; p < 0.001) and interarterial course (11 vs. 0; p < 0.001) than 22 (41 %) and 13 (24 %) individuals with abnormal circumflex artery (ALCx) and left coronary artery (ALCA) origin, respectively. Patients with ALCA presented less frequently with chest pain than subjects with ARCA and ALCx (25 vs. 3; p = 0.03). Patients with ARCA tended to show higher occurrence of cardiac events in the follow-up than individuals with ALCA and ALCx (5 vs. 4; p = NS). High-risk anatomy features are most common in patients with ARCA and these patients also have higher prevalence of chest pain and cardiac events in the follow-up than individuals with ALCA and ALCx. (orig.)

Organic Chemistry YouTube Writing Assignment for Large Lecture Classes

Science.gov (United States)

Franz, Annaliese K.

2012-01-01

This work describes efforts to incorporate and evaluate the use of a YouTube writing assignment in large lecture classes to personalize learning and improve conceptual understanding of chemistry through peer- and self-explanation strategies. Although writing assignments can be a method to incorporate peer- and self-explanation strategies, this…

Negotiating Languages and Cultures: Enacting Translingualism through a Translation Assignment

Science.gov (United States)

Kiernan, Julia; Meier, Joyce; Wang, Xiqiao

2016-01-01

This collaborative project explores the affordances of a translation assignment in the context of a learner-centered pedagogy that places composition students' movement among languages and cultures as both a site for inquiry and subject of analysis. The translation assignment asks students to translate scholarly articles or culture stories from…

Students' Evaluation of Writing Assignments in an Abnormal Psychology Course.

Science.gov (United States)

Procidano, Mary E.

1991-01-01

Presents a study in which students in an abnormal psychology class rated the usefulness of drafts for two writing assignments. Reports that a research proposal was more effective than a case study in generating interest in psychology and opportunity for creativity. Concludes that writing assignments should reflect important aspects of a…

Bacteria as bullies: effects of linguistic agency assignment in health message.

Science.gov (United States)

Bell, Robert A; McGlone, Matthew S; Dragojevic, Marko

2014-01-01

When describing health threats, communicators can assign agency to the threat (e.g., "Hepatitis C has infected 4 million Americans") or to humans (e.g., "Four million Americans have contracted hepatitis C"). In an online experiment, the authors explored how assignment of agency affects perceptions of susceptibility and severity of a health threat, response efficacy, self-efficacy, fear arousal, and intentions to adopt health-protective recommendations. Participants were 719 individuals recruited through Mechanical Turk ( www.mturk.com ), a crowdsource labor market run by Amazon ( www.amazon.com ). The participants were assigned randomly to read 1 of 8 flyers defined by a 2×4 (Agency Assignment×Topic) factorial design. Each flyer examined 1 health threat (E. coli, necrotizing fasciitis, salmonella, or Carbapenem-resistant Klebsiella pneumoniae) and was written in language that emphasized bacterial or human agency. Perceived susceptibility and severity were highest when bacterial agency language was used. Response efficacy, self-efficacy, and fear arousal were not significantly affected by agency assignment. Participants reported stronger intentions to adopt recommendations when bacteria agency language was used, but this effect did not reach conventional standards of significance (p < .051). The authors concluded that health communicators can increase target audiences' perceptions of susceptibility and severity by assigning agency to the threat in question when devising health messages.

De-stoning technology for improving olive oil nutritional and sensory features: The right idea at the wrong time.

Science.gov (United States)

Restuccia, Donatella; Clodoveo, Maria Lisa; Corbo, Filomena; Loizzo, Monica Rosa

2018-04-01

De-stoning technology has been introduced in the olive oil sector more than twenty years ago. It has not gained momentum because, sometimes, innovative ideas are not accepted since they are suggested at the wrong time or under the wrong circumstances. Virgin olive oil (VOO) is one of the most popular functional foods, mainly due to its antioxidant properties. These features, as well as other nutritional characteristics are generally enhanced by the de-stoning process. However, despite the improvement of the nutritional value, in the past the de-stoned oil didn't achieve marketing success mainly in relation to technological limitations (i.e. low oil yield). Only in recent years healthy properties became an element able to influence consumers' behavior, overcoming the limit of low oil yields and attracting the attention of olive oil producers. An analysis of the advantages, in terms of product quality and process sustainability, is given in this review. Here, for the first time, the fragmented results reported in literature are critically analyzed underlining the contradictions reported by different authors showing the main reasons for the unlucky fate of this technology in the industrial sector. In the final section the challenges, that future research must focus on, are presented, including emerging technologies in VOO processing. Literature data, for the first time discussed here exhaustively, show that de-stoning technology is a mechanical strategy useful to increase the nutritional and the sensory quality of the product. Moreover, it reduces the depletion of natural resources obtaining a selective crushing of the drupe by removing the stones from the olive paste so increasing the sustainability and efficiency of VOO extraction plants. Copyright © 2018 Elsevier Ltd. All rights reserved.

A Stone Resource Assignment Model under the Fuzzy Environment

Directory of Open Access Journals (Sweden)

Liming Yao

2012-01-01

to tackle a stone resource assignment problem with the aim of decreasing dust and waste water emissions. On the upper level, the local government wants to assign a reasonable exploitation amount to each stone plant so as to minimize total emissions and maximize employment and economic profit. On the lower level, stone plants must reasonably assign stone resources to produce different stone products under the exploitation constraint. To deal with inherent uncertainties, the object functions and constraints are defuzzified using a possibility measure. A fuzzy simulation-based improved simulated annealing algorithm (FS-ISA is designed to search for the Pareto optimal solutions. Finally, a case study is presented to demonstrate the practicality and efficiency of the model. Results and a comparison analysis are presented to highlight the performance of the optimization method, which proves to be very efficient compared with other algorithms.

Wildlife forensic science: A review of genetic geographic origin assignment.

Science.gov (United States)

Ogden, Rob; Linacre, Adrian

2015-09-01

Wildlife forensic science has become a key means of enforcing legislation surrounding the illegal trade in protected and endangered species. A relatively new dimension to this area of forensic science is to determine the geographic origin of a seized sample. This review focuses on DNA testing, which relies on assignment of an unknown sample to its genetic population of origin. Key examples of this are the trade in timber, fish and ivory and these are used only to illustrate the large number of species for which this type of testing is potentially available. The role of mitochondrial and nuclear DNA markers is discussed, alongside a comparison of neutral markers with those exhibiting signatures of selection, which potentially offer much higher levels of assignment power to address specific questions. A review of assignment tests is presented along with detailed methods for evaluating error rates and considerations for marker selection. The availability and quality of reference data are of paramount importance to support assignment applications and ensure reliability of any conclusions drawn. The genetic methods discussed have been developed initially as investigative tools but comment is made regarding their use in courts. The potential to compliment DNA markers with elemental assays for greater assignment power is considered and finally recommendations are made for the future of this type of testing. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

Reflective practice: assessment of assignments in English for Specific Purposes

Directory of Open Access Journals (Sweden)

Galina Kavaliauskiené

2007-10-01

Full Text Available The construct alternative assessment has been widely used in higher education. It is often defined as any type of assessment of learners who provide a response to an assignment. The key features of alternative assessment are active participation of learners in self-evaluation of their performance, and the development of reflective thinking through reflective thinking (Schön, 1983. The success of alternative assessment in language teaching is predetermined by student’s performance and demonstrates learner’s language proficiency in contemporary communicative classrooms. This paper aims at researching the influence of students’ evaluations of various assignments for their linguistic development in English for Specific Purposes (ESP. The study uses learners’ assessment of different assignments and learners’ in-course and post-course written reflections on benefits to language mastery. Learners’ assignments included were contributions to portfolios (dossiers, such as essays and summaries, oral presentations, short impromptu talks, creative tasks, tests, and self-assessment notes (reflections on activities in learning ESP. Findings were obtained for two streams of the project participants. Results showed that self-assessment was beneficial for learners’ linguistic development. The context of learners’ reflections reveals that the attitudes to various assignments are affected by success or failure in students’ performance. Reflective practice might help teachers develop ways of dealing with previously identified difficulties and improve the quality of teaching.

Teaching Complaint and Adjustment Letters--And Tact (My Favorite Assignment).

Science.gov (United States)

Deimling, Paula

1992-01-01

Describes a three-part assignment in which each student writes a complaint letter and an adjustment letter responding to another student's complaint letter. Discusses how the third part of the assignment--journal entries--allows students to formulate their own criteria for excellent letters based upon their reactions to the letters they receive.…

On the Use of Writing Assignments in Intermediate Microeconomic Theory

Science.gov (United States)

O'Neill, Patrick B.

2009-01-01

A typical writing assignment in upper level required courses is a term paper. However many economics majors, particularly those in business schools, need to develop skill at writing shorter pieces. In this paper I describe numerous examples of shorter writing assignments that I have incorporated into an Intermediate Microeconomic Theory course.…

Probabilistic validation of protein NMR chemical shift assignments

International Nuclear Information System (INIS)

Dashti, Hesam; Tonelli, Marco; Lee, Woonghee; Westler, William M.; Cornilescu, Gabriel; Ulrich, Eldon L.; Markley, John L.

2016-01-01

Data validation plays an important role in ensuring the reliability and reproducibility of studies. NMR investigations of the functional properties, dynamics, chemical kinetics, and structures of proteins depend critically on the correctness of chemical shift assignments. We present a novel probabilistic method named ARECA for validating chemical shift assignments that relies on the nuclear Overhauser effect data. ARECA has been evaluated through its application to 26 case studies and has been shown to be complementary to, and usually more reliable than, approaches based on chemical shift databases. ARECA is available online at http://areca.nmrfam.wisc.edu/ http://areca.nmrfam.wisc.edu/

Probabilistic validation of protein NMR chemical shift assignments

Energy Technology Data Exchange (ETDEWEB)

Dashti, Hesam [University of Wisconsin-Madison, Graduate Program in Biophysics, Biochemistry Department (United States); Tonelli, Marco; Lee, Woonghee; Westler, William M.; Cornilescu, Gabriel [University of Wisconsin-Madison, Biochemistry Department, National Magnetic Resonance Facility at Madison (United States); Ulrich, Eldon L. [University of Wisconsin-Madison, BioMagResBank, Biochemistry Department (United States); Markley, John L., E-mail: markley@nmrfam.wisc.edu, E-mail: jmarkley@wisc.edu [University of Wisconsin-Madison, Biochemistry Department, National Magnetic Resonance Facility at Madison (United States)

2016-01-15

Data validation plays an important role in ensuring the reliability and reproducibility of studies. NMR investigations of the functional properties, dynamics, chemical kinetics, and structures of proteins depend critically on the correctness of chemical shift assignments. We present a novel probabilistic method named ARECA for validating chemical shift assignments that relies on the nuclear Overhauser effect data. ARECA has been evaluated through its application to 26 case studies and has been shown to be complementary to, and usually more reliable than, approaches based on chemical shift databases. ARECA is available online at http://areca.nmrfam.wisc.edu/ http://areca.nmrfam.wisc.edu/.

Optimal Processor Assignment for Pipeline Computations

Science.gov (United States)

1991-10-01

the use of ratios: initially each task is assigned a procesbuor2 the remaining proceborb are distributed in proportion to the quantities f,(1), 1 < i...algorithmns. IEEE Trans. onl Parallel and Distributed Systemns, 1 (4):470-499, October 1990. [26] P. Al. Kogge. The Architeture of Pipelined Comnputers

7 CFR 1437.104 - Assigned production.

Science.gov (United States)

2010-01-01

...) Irrigation equipment is not capable of supplying adequate water to sustain the expected production of a... practice is not used. (7) For normal irrigated annual and biennial crops, the supply of available water at... determining losses under this section, assigned production will be used to offset the loss of production when...

41 CFR 102-79.20 - What standard must Executive agencies promote when assigning space?

Science.gov (United States)

2010-07-01

... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false What standard must Executive agencies promote when assigning space? 102-79.20 Section 102-79.20 Public Contracts and Property... PROPERTY 79-ASSIGNMENT AND UTILIZATION OF SPACE Assignment and Utilization of Space Assignment of Space...

Assigning Main Orientation to an EOH Descriptor on Multispectral Images

Directory of Open Access Journals (Sweden)

Yong Li

2015-07-01

Full Text Available This paper proposes an approach to compute an EOH (edge-oriented histogram descriptor with main orientation. EOH has a better matching ability than SIFT (scale-invariant feature transform on multispectral images, but does not assign a main orientation to keypoints. Alternatively, it tends to assign the same main orientation to every keypoint, e.g., zero degrees. This limits EOH to matching keypoints between images of translation misalignment only. Observing this limitation, we propose assigning to keypoints the main orientation that is computed with PIIFD (partial intensity invariant feature descriptor. In the proposed method, SIFT keypoints are detected from images as the extrema of difference of Gaussians, and every keypoint is assigned to the main orientation computed with PIIFD. Then, EOH is computed for every keypoint with respect to its main orientation. In addition, an implementation variant is proposed for fast computation of the EOH descriptor. Experimental results show that the proposed approach performs more robustly than the original EOH on image pairs that have a rotation misalignment.

Saying the Wrong Thing: Improving Learning with Multimedia by Including Misconceptions

Science.gov (United States)

Muller, D. A.; Bewes, J.; Sharma, M. D.; Reimann, P.

2008-01-01

In this study, 364 first-year physics students were randomly assigned to one of four online multimedia treatments on Newton's First and Second Laws of Motion: (1) the "Exposition", a concise lecture-style presentation; (2) the "Extended Exposition", the Exposition with additional interesting information; (3) the "Refutation", the Exposition with…

46 CFR 42.05-10 - Assigning authority.

Science.gov (United States)

2010-10-01

... Definition of Terms Used in This Subchapter § 42.05-10 Assigning authority. This term means the “American Bureau of Shipping” or such other recognized classification society which the Commandant may approve as...

Automation of block assignment planning using a diagram-based scenario modeling method

Directory of Open Access Journals (Sweden)

In Hyuck Hwang

2014-03-01

Full Text Available Most shipbuilding scheduling research so far has focused on the load level on the dock plan. This is because the dock is the least extendable resource in shipyards, and its overloading is difficult to resolve. However, once dock scheduling is completed, making a plan that makes the best use of the rest of the resources in the shipyard to minimize any additional cost is also important. Block assignment planning is one of the midterm planning tasks; it assigns a block to the facility (factory/shop or surface plate that will actually manufacture the block according to the block characteristics and current situation of the facility. It is one of the most heavily loaded midterm planning tasks and is carried out manually by experienced workers. In this study, a method of representing the block assignment rules using a diagram was suggested through analysis of the existing manual process. A block allocation program was developed which automated the block assignment process according to the rules represented by the diagram. The planning scenario was validated through a case study that compared the manual assignment and two automated block assignment results.

Automation of block assignment planning using a diagram-based scenario modeling method

Directory of Open Access Journals (Sweden)

Hwang In Hyuck

2014-03-01

Full Text Available Most shipbuilding scheduling research so far has focused on the load level on the dock plan. This is be¬cause the dock is the least extendable resource in shipyards, and its overloading is difficult to resolve. However, once dock scheduling is completed, making a plan that makes the best use of the rest of the resources in the shipyard to minimize any additional cost is also important. Block assignment planning is one of the midterm planning tasks; it assigns a block to the facility (factory/shop or surface plate that will actually manufacture the block according to the block characteristics and current situation of the facility. It is one of the most heavily loaded midterm planning tasks and is carried out manu¬ally by experienced workers. In this study, a method of representing the block assignment rules using a diagram was su¬ggested through analysis of the existing manual process. A block allocation program was developed which automated the block assignment process according to the rules represented by the diagram. The planning scenario was validated through a case study that compared the manual assignment and two automated block assignment results.

An Accurate and Impartial Expert Assignment Method for Scientific Project Review

Directory of Open Access Journals (Sweden)

Mingliang Yue

2017-12-01

Full Text Available Purpose: This paper proposes an expert assignment method for scientific project review that considers both accuracy and impartiality. As impartial and accurate peer review is extremely important to ensure the quality and feasibility of scientific projects, enhanced methods for managing the process are needed. Design/methodology/approach: To ensure both accuracy and impartiality, we design four criteria, the reviewers’ fitness degree, research intensity, academic association, and potential conflict of interest, to express the characteristics of an appropriate peer review expert. We first formalize the expert assignment problem as an optimization problem based on the designed criteria, and then propose a randomized algorithm to solve the expert assignment problem of identifying reviewer adequacy. Findings: Simulation results show that the proposed method is quite accurate and impartial during expert assignment. Research limitations: Although the criteria used in this paper can properly show the characteristics of a good and appropriate peer review expert, more criteria/conditions can be included in the proposed scheme to further enhance accuracy and impartiality of the expert assignment. Practical implications: The proposed method can help project funding agencies (e.g. the National Natural Science Foundation of China find better experts for project peer review. Originality/value: To the authors’ knowledge, this is the first publication that proposes an algorithm that applies an impartial approach to the project review expert assignment process. The simulation results show the effectiveness of the proposed method.

A Web Support System for Submission and Handling of Programming Assignments

DEFF Research Database (Denmark)

Nørmark, Kurt

2011-01-01

Individual submission of programming assignments should be considered in all introductory programming courses. We describe a custom web support system for submission and management of programming assignments in an introductory C programming course. Experience from the first time use of the system...... is reported. In addition, we compare the pattern of use with the results of the final exam in order to reveal a possible impact of the programming assignments. We summarize the lessons learned in preparation for improving the system prior to the next round of use in the fall of 2011....

Assigned experts with competitive goals withhold information in group decision making

NARCIS (Netherlands)

Toma, C.; Vasiljevic, D.; Oberlé, D.; Butera, F.

2013-01-01

Expertise assignment has been proposed to improve unshared information pooling in group decision making. The current research revises this view by hypothesizing that expertise assignment is beneficial when group members have cooperative goals, but is detrimental when group members have competitive

Assignment methodology for larger RNA oligonucleotides: Application to an ATP-binding RNA aptamer

International Nuclear Information System (INIS)

Dieckmann, Thorsten; Feigon, Juli

1997-01-01

The use of uniform 13C, 15N labeling in the NMR spectroscopic study of RNA structures has greatly facilitated the assignment process in small RNA oligonucleotides. For ribose spinsystem assignments, exploitation of these labels has followed previously developed methods for the study of proteins. However, for sequential assignment of the exchangeable and nonexchangeable protons of the nucleotides, it has been necessary to develop a variety of new NMR experiments. Even these are of limited utility in the unambiguous assignment of larger RNAs due to the short carbon relaxation times and extensive spectral overlap for all nuclei.These problems can largely be overcome by the additional use of base-type selectively 13C, 15N-labeled RNA in combination with a judicious use of related RNAs with base substitutions. We report the application of this approach to a 36-nucleotide ATP-binding RNA aptamer in complex with AMP. Complete sequential 1H assignments, as well as the majority of 13C and 15N assignments, were obtained

AUTOBA: automation of backbone assignment from HN(C)N suite of experiments.

Science.gov (United States)

Borkar, Aditi; Kumar, Dinesh; Hosur, Ramakrishna V

2011-07-01

Development of efficient strategies and automation represent important milestones of progress in rapid structure determination efforts in proteomics research. In this context, we present here an efficient algorithm named as AUTOBA (Automatic Backbone Assignment) designed to automate the assignment protocol based on HN(C)N suite of experiments. Depending upon the spectral dispersion, the user can record 2D or 3D versions of the experiments for assignment. The algorithm uses as inputs: (i) protein primary sequence and (ii) peak-lists from user defined HN(C)N suite of experiments. In the end, one gets H(N), (15)N, C(α) and C' assignments (in common BMRB format) for the individual residues along the polypeptide chain. The success of the algorithm has been demonstrated, not only with experimental spectra recorded on two small globular proteins: ubiquitin (76 aa) and M-crystallin (85 aa), but also with simulated spectra of 27 other proteins using assignment data from the BMRB.

Epidemiological tracking and population assignment of the non-clonal bacterium, Burkholderia pseudomallei.

Science.gov (United States)

Dale, Julia; Price, Erin P; Hornstra, Heidie; Busch, Joseph D; Mayo, Mark; Godoy, Daniel; Wuthiekanun, Vanaporn; Baker, Anthony; Foster, Jeffrey T; Wagner, David M; Tuanyok, Apichai; Warner, Jeffrey; Spratt, Brian G; Peacock, Sharon J; Currie, Bart J; Keim, Paul; Pearson, Talima

2011-12-01

Rapid assignment of bacterial pathogens into predefined populations is an important first step for epidemiological tracking. For clonal species, a single allele can theoretically define a population. For non-clonal species such as Burkholderia pseudomallei, however, shared allelic states between distantly related isolates make it more difficult to identify population defining characteristics. Two distinct B. pseudomallei populations have been previously identified using multilocus sequence typing (MLST). These populations correlate with the major foci of endemicity (Australia and Southeast Asia). Here, we use multiple Bayesian approaches to evaluate the compositional robustness of these populations, and provide assignment results for MLST sequence types (STs). Our goal was to provide a reference for assigning STs to an established population without the need for further computational analyses. We also provide allele frequency results for each population to enable estimation of population assignment even when novel STs are discovered. The ability for humans and potentially contaminated goods to move rapidly across the globe complicates the task of identifying the source of an infection or outbreak. Population genetic dynamics of B. pseudomallei are particularly complicated relative to other bacterial pathogens, but the work here provides the ability for broad scale population assignment. As there is currently no independent empirical measure of successful population assignment, we provide comprehensive analytical details of our comparisons to enable the reader to evaluate the robustness of population designations and assignments as they pertain to individual research questions. Finer scale subdivision and verification of current population compositions will likely be possible with genotyping data that more comprehensively samples the genome. The approach used here may be valuable for other non-clonal pathogens that lack simple group-defining genetic characteristics

Epidemiological tracking and population assignment of the non-clonal bacterium, Burkholderia pseudomallei.

Directory of Open Access Journals (Sweden)

Julia Dale

2011-12-01

Full Text Available Rapid assignment of bacterial pathogens into predefined populations is an important first step for epidemiological tracking. For clonal species, a single allele can theoretically define a population. For non-clonal species such as Burkholderia pseudomallei, however, shared allelic states between distantly related isolates make it more difficult to identify population defining characteristics. Two distinct B. pseudomallei populations have been previously identified using multilocus sequence typing (MLST. These populations correlate with the major foci of endemicity (Australia and Southeast Asia. Here, we use multiple Bayesian approaches to evaluate the compositional robustness of these populations, and provide assignment results for MLST sequence types (STs. Our goal was to provide a reference for assigning STs to an established population without the need for further computational analyses. We also provide allele frequency results for each population to enable estimation of population assignment even when novel STs are discovered. The ability for humans and potentially contaminated goods to move rapidly across the globe complicates the task of identifying the source of an infection or outbreak. Population genetic dynamics of B. pseudomallei are particularly complicated relative to other bacterial pathogens, but the work here provides the ability for broad scale population assignment. As there is currently no independent empirical measure of successful population assignment, we provide comprehensive analytical details of our comparisons to enable the reader to evaluate the robustness of population designations and assignments as they pertain to individual research questions. Finer scale subdivision and verification of current population compositions will likely be possible with genotyping data that more comprehensively samples the genome. The approach used here may be valuable for other non-clonal pathogens that lack simple group-defining genetic

The game you are in: Misleading through social norms and what’s wrong with it

Directory of Open Access Journals (Sweden)

Herzog Lisa

2017-01-01

Full Text Available This paper discusses the phenomenon of misleading about “the game you are in.” Individuals who mislead others in this way draw on the fact that we rely on social norms for regulating the levels of alertness, openness, and trust we use in different epistemic situations. By pretending to be in a certain game with a certain epistemic situation, they can entice others to reveal information or to exhibit low levels of alertness, thereby acting against their own interests. I delineate this phenomenon from direct lies and acts of misleading by implication, and discuss some variations of it. I then ask why and under what conditions it is morally wrong to mislead others about the game they are in. I distinguish three normative angles for understanding the phenomenon: deontological constraints, free-riding on a shared cultural infrastructure, and implicit discrimination against outsiders and atypical candidates. I conclude by briefly discussing some practical implications.

Practical aspects of NMR signal assignment in larger and challenging proteins

Science.gov (United States)

Frueh, Dominique P.

2014-01-01

NMR has matured into a technique routinely employed for studying proteins in near physiological conditions. However, applications to larger proteins are impeded by the complexity of the various correlation maps necessary to assign NMR signals. This article reviews the data analysis techniques traditionally employed for resonance assignment and describes alternative protocols necessary for overcoming challenges in large protein spectra. In particular, simultaneous analysis of multiple spectra may help overcome ambiguities or may reveal correlations in an indirect manner. Similarly, visualization of orthogonal planes in a multidimensional spectrum can provide alternative assignment procedures. We describe examples of such strategies for assignment of backbone, methyl, and nOe resonances. We describe experimental aspects of data acquisition for the related experiments and provide guidelines for preliminary studies. Focus is placed on large folded monomeric proteins and examples are provided for 37, 48, 53, and 81 kDa proteins. PMID:24534088

Beta-Test Data On An Assessment Of Textbook Problem Solving Ability: An Argument For Right/Wrong Grading?

Science.gov (United States)

Cummings, Karen; Marx, Jeffrey D.

2010-10-01

We have developed an assessment of students' ability to solve standard textbook style problems and are currently engaged in the validation and revision process. The assessment covers the topics of force and motion, conservation of momentum and conservation of energy at a level consistent with most calculus-based, introductory physics courses. This tool is discussed in more detail in an accompanying paper by Marx and Cummings. [1] Here we present preliminary beta-test data collected at four schools during the 2009/2010 academic year. Data include both pre- and post-instruction results for introductory physics courses as well as results for physics majors in later years. In addition, we present evidence that right/wrong grading may well be a perfectly acceptable grading procedure for a course-level assessment of this type.

Applications of random forest feature selection for fine-scale genetic population assignment.

Science.gov (United States)

Sylvester, Emma V A; Bentzen, Paul; Bradbury, Ian R; Clément, Marie; Pearce, Jon; Horne, John; Beiko, Robert G

2018-02-01

Genetic population assignment used to inform wildlife management and conservation efforts requires panels of highly informative genetic markers and sensitive assignment tests. We explored the utility of machine-learning algorithms (random forest, regularized random forest and guided regularized random forest) compared with F ST ranking for selection of single nucleotide polymorphisms (SNP) for fine-scale population assignment. We applied these methods to an unpublished SNP data set for Atlantic salmon ( Salmo salar ) and a published SNP data set for Alaskan Chinook salmon ( Oncorhynchus tshawytscha ). In each species, we identified the minimum panel size required to obtain a self-assignment accuracy of at least 90% using each method to create panels of 50-700 markers Panels of SNPs identified using random forest-based methods performed up to 7.8 and 11.2 percentage points better than F ST -selected panels of similar size for the Atlantic salmon and Chinook salmon data, respectively. Self-assignment accuracy ≥90% was obtained with panels of 670 and 384 SNPs for each data set, respectively, a level of accuracy never reached for these species using F ST -selected panels. Our results demonstrate a role for machine-learning approaches in marker selection across large genomic data sets to improve assignment for management and conservation of exploited populations.

10 CFR Appendix A to Part 20 - Assigned Protection Factors for Respirators a

Science.gov (United States)

2010-01-01

... internal dose due to inhalation may, in addition, present external exposure hazards at higher... 10 Energy 1 2010-01-01 2010-01-01 false Assigned Protection Factors for Respirators a A Appendix A..., App. A Appendix A to Part 20—Assigned Protection Factors for Respirators a Operating mode Assigned...

Optimisation of timetable-based, stochastic transit assignment models based on MSA

DEFF Research Database (Denmark)

Nielsen, Otto Anker; Frederiksen, Rasmus Dyhr

2006-01-01

(CRM), such a large-scale transit assignment model was developed and estimated. The Stochastic User Equilibrium problem was solved by the Method of Successive Averages (MSA). However, the model suffered from very large calculation times. The paper focuses on how to optimise transit assignment models...

48 CFR 832.805-70 - Distribution/notification of assignment of claims.

Science.gov (United States)

2010-10-01

... assignment of payments for contracts under which payment for articles and services is certified and approved... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Distribution/notification... DEPARTMENT OF VETERANS AFFAIRS GENERAL CONTRACTING REQUIREMENTS CONTRACT FINANCING Assignment of Claims 832...

Danish Public Construction Counselling Selection and Assignment Criteria in European Tendering

DEFF Research Database (Denmark)

Larsen, Jesper Kranker; Ussing, Lene Faber; Brunø, Thomas Ditlev

2014-01-01

One of the largest customers in the Danish construction industry is public agencies that own and develop projects. For some of the counselling services, they recur to be put out in European tendering. The aim is to find which selection and assignment criteria are used most in public tendering. How...... projects use selection and assignment criteria for counselling services and finally if there is significant use of selection and assignment methods in public counselling. The method is based on 74 public counselling tenders from the European Tenders Electronic Daily database from January 2010 to March 2013...

Controversies of Sex Re-assignment in Genetic Males with Congenital Inadequacy of the Penis.

Science.gov (United States)

Raveenthiran, Venkatachalam

2017-09-01

Sex assignment in 46XY genetic male children with congenital inadequacy of the penis (CIP) is controversial. Traditionally, children with penile length less than 2 cm at birth are considered unsuitable to be raised as males. They are typically re-assigned to female-sex and feminizing genitoplasty is usually done in infancy. However, the concept of cerebral androgen imprinting has caused paradigm shift in the philosophy of sex re-assignment. Masculinization of the brain, rather than length of the penis, is the modern criterion of sex re-assignment in CIP. This review summarizes the current understanding of the complex issue. In 46XY children with CIP, male-sex assignment appears appropriate in non-hormonal conditions such as idiopathic micropenis, aphallia and exstrophy. Female-sex re-assignment appears acceptable in complete androgen insensitivity (CAIS), while partial androgen insensitivity syndrome (PAIS) patients are highly dissatisfied with the assignment of either sex. Children with 5-alpha reductase deficiency are likely to have spontaneous penile lengthening at puberty. Hence, they are better raised as males. Although female assignment is common in pure gonadal dysgenesis, long-term results are not known to justify the decision.

Work assignments, delegation of tasks and job satisfaction among Danish dental hygienists.

Science.gov (United States)

Hach, M; Aaberg, K B; Lempert, S M; Danielsen, B

2017-08-01

Recent legislation in Denmark has made it possible for dentists to delegate their tasks to dental hygienists. Previous studies have shown that Danish dental hygienists primarily were performing assignments within their own work field. These assignments include prophylaxis or instructing patients in oral health care. However, studies have also shown that Danish dental hygienists performed dental nurse assignments such as chair-side assistance, unit cleaning and disinfection of instruments. The objectives of this study were to investigate (i) the range of work assignments performed by Danish dental hygienists, (ii) the types of dentist tasks performed by Danish dental hygienists and (iii) job satisfaction among Danish dental hygienists. Dental hygienists graduating in 2004-2007 were invited to participate in this study. Participants answered an email-distributed questionnaire. The questionnaire consisted of questions regarding job satisfaction, assignments performed, postgraduate course attendance, receiving assistance from a dental nurse and which work assignments Danish dental hygienists wish to perform in the future. The results of this study showed that 90% of Danish dental hygienists were satisfied with their job and 52% were performing dentists' tasks. Among dentists' tasks performed by Danish dental hygienists, invasive caries therapy was the most frequently performed task. The type of assignments performed by Danish dental hygienists today appears to be changing compared to previous studies. From initially performing prophylaxis and chair-side assistance for the dentist, Danish dental hygienists today are performing a wider range of tasks which includes dentists' tasks. © 2016 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Model morphing and sequence assignment after molecular replacement.

Science.gov (United States)

Terwilliger, Thomas C; Read, Randy J; Adams, Paul D; Brunger, Axel T; Afonine, Pavel V; Hung, Li-Wei

2013-11-01

A procedure termed `morphing' for improving a model after it has been placed in the crystallographic cell by molecular replacement has recently been developed. Morphing consists of applying a smooth deformation to a model to make it match an electron-density map more closely. Morphing does not change the identities of the residues in the chain, only their coordinates. Consequently, if the true structure differs from the working model by containing different residues, these differences cannot be corrected by morphing. Here, a procedure that helps to address this limitation is described. The goal of the procedure is to obtain a relatively complete model that has accurate main-chain atomic positions and residues that are correctly assigned to the sequence. Residues in a morphed model that do not match the electron-density map are removed. Each segment of the resulting trimmed morphed model is then assigned to the sequence of the molecule using information about the connectivity of the chains from the working model and from connections that can be identified from the electron-density map. The procedure was tested by application to a recently determined structure at a resolution of 3.2 Å and was found to increase the number of correctly identified residues in this structure from the 88 obtained using phenix.resolve sequence assignment alone (Terwilliger, 2003) to 247 of a possible 359. Additionally, the procedure was tested by application to a series of templates with sequence identities to a target structure ranging between 7 and 36%. The mean fraction of correctly identified residues in these cases was increased from 33% using phenix.resolve sequence assignment to 47% using the current procedure. The procedure is simple to apply and is available in the Phenix software package.

Disentangling Mathematics Target and Access Skills: Implications for Accommodation Assignment Practices

Science.gov (United States)

Ketterlin-Geller, Leanne R.; Jamgochian, Elisa M.; Nelson-Walker, Nancy J.; Geller, Joshua P.

2012-01-01

Appropriate assignment of accommodations is predicated on a clear distinction between target skills and access skills. In this study, we examine the agreement between test developer/researchers' and educators' classification of target and access skills as a possible explanatory mechanism for assigning accommodations. Findings indicate that…

Written Assignments for Abnormal Psychology at Howard Community College, Fall 1988.

Science.gov (United States)

Bell, James

Designed for students enrolled in an Abnormal Psychology course at Howard Community College (Maryland), this booklet explains the requirements for the course's writing assignments, which are designed to teach the skills of comparison and contrast, analysis, critical thinking, and synthesis. Following an overview of class assignments and…

Improving Students’ Learning in Software Engineering Education through Multi-Level Assignments

NARCIS (Netherlands)

Dr. Leo Pruijt; Christian Köppe

2014-01-01

Author supplied: DOI : http://dx.doi.org/10.1145/2691352.2691357 Assignments and exercises are an essential part of software engineering education. It usually requires a variety of these assignments to cover a desired wide range of educational objectives as defined in the revised Bloom's taxonomy.

The edge complex: implicit memory for figure assignment in shape perception.

Science.gov (United States)

Peterson, Mary A; Enns, James T

2005-05-01

Viewing a stepped edge is likely to prompt the perceptual assignment of one side of the edge as figure. This study demonstrates that even a single brief glance at a novel edge gives rise to an implicit memory regarding which side was seen as figure; this edge complex enters into the figure assignment process the next time the edge is encountered, both speeding same-different judgments when the figural side is repeated and slowing these judgments when the new figural side is identical to the former ground side (Experiments 1A and 1B). These results were obtained even when the facing direction of the repeated edge was mirror reversed (Experiment 2). This study shows that implicit measures can reveal the effects of past experience on figure assignment, following a single prior exposure to a novel shape, and supports a competitive model of figure assignment in which past experience serves as one of many figural cues.

A Statistical Programme Assignment Model

DEFF Research Database (Denmark)

Rosholm, Michael; Staghøj, Jonas; Svarer, Michael

When treatment effects of active labour market programmes are heterogeneous in an observable way  across the population, the allocation of the unemployed into different programmes becomes a particularly  important issue. In this paper, we present a statistical model designed to improve the present...... duration of unemployment spells may result if a statistical programme assignment model is introduced. We discuss several issues regarding the  plementation of such a system, especially the interplay between the statistical model and  case workers....

Integrated project scheduling and staff assignment with controllable processing times.

Science.gov (United States)

Fernandez-Viagas, Victor; Framinan, Jose M

2014-01-01

This paper addresses a decision problem related to simultaneously scheduling the tasks in a project and assigning the staff to these tasks, taking into account that a task can be performed only by employees with certain skills, and that the length of each task depends on the number of employees assigned. This type of problems usually appears in service companies, where both tasks scheduling and staff assignment are closely related. An integer programming model for the problem is proposed, together with some extensions to cope with different situations. Additionally, the advantages of the controllable processing times approach are compared with the fixed processing times. Due to the complexity of the integrated model, a simple GRASP algorithm is implemented in order to obtain good, approximate solutions in short computation times.

Integrated Project Scheduling and Staff Assignment with Controllable Processing Times

Directory of Open Access Journals (Sweden)

Victor Fernandez-Viagas

2014-01-01

Full Text Available This paper addresses a decision problem related to simultaneously scheduling the tasks in a project and assigning the staff to these tasks, taking into account that a task can be performed only by employees with certain skills, and that the length of each task depends on the number of employees assigned. This type of problems usually appears in service companies, where both tasks scheduling and staff assignment are closely related. An integer programming model for the problem is proposed, together with some extensions to cope with different situations. Additionally, the advantages of the controllable processing times approach are compared with the fixed processing times. Due to the complexity of the integrated model, a simple GRASP algorithm is implemented in order to obtain good, approximate solutions in short computation times.

The Automatic Sweetheart: An Assignment in a History of Psychology Course

Science.gov (United States)

Sibicky, Mark E.

2007-01-01

This article describes an assignment in a History of Psychology course used to enhance student retention of material and increase student interest and discussion of the long-standing debate between humanistic and mechanistic models in psychology. Adapted from William James's (1955) automatic sweetheart question, the assignment asks students to…

A Case-Study Assignment to Teach Theoretical Perspectives in Abnormal Psychology.

Science.gov (United States)

Perkins, David V.

1991-01-01

Describes an assignment that requires students to organize, prepare, and revise a case study in abnormal behavior. Explains that students employ a single theoretical perspective in preparing a report on a figure from history, literature, the arts, or current events. Discusses the value of the assignment for students. (SG)

Quality Assurance of UMLS Semantic Type Assignments Using SNOMED CT Hierarchies.

Science.gov (United States)

Gu, H; Chen, Y; He, Z; Halper, M; Chen, L

2016-01-01

The Unified Medical Language System (UMLS) is one of the largest biomedical terminological systems, with over 2.5 million concepts in its Metathesaurus repository. The UMLS's Semantic Network (SN) with its collection of 133 high-level semantic types serves as an abstraction layer on top of the Metathesaurus. In particular, the SN elaborates an aspect of the Metathesaurus's concepts via the assignment of one or more types to each concept. Due to the scope and complexity of the Metathesaurus, errors are all but inevitable in this semantic-type assignment process. To develop a semi-automated methodology to help assure the quality of semantic-type assignments within the UMLS. The methodology uses a cross-validation strategy involving SNOMED CT's hierarchies in combination with UMLS semantic types. Semantically uniform, disjoint concept groups are generated programmatically by partitioning the collection of all concepts in the same SNOMED CT hierarchy according to their respective semantic-type assignments in the UMLS. Domain experts are then called upon to review the concepts in any group having a small number of concepts. It is our hypothesis that a semantic-type assignment combination applicable only to a very small number of concepts in a SNOMED CT hierarchy is an indicator of potential problems. The methodology was applied to the UMLS 2013AA release along with the SNOMED CT from January 2013. An overall error rate of 33% was found for concepts proposed by the quality-assurance methodology. Supporting our hypothesis, that number was four times higher than the error rate found in control samples. The results show that the quality-assurance methodology can aid in effective and efficient identification of UMLS semantic-type assignment errors.

ZAP: a distributed channel assignment algorithm for cognitive radio networks

OpenAIRE

Junior , Paulo Roberto ,; Fonseca , Mauro; Munaretto , Anelise; Viana , Aline ,; Ziviani , Artur

2011-01-01

Abstract We propose ZAP, an algorithm for the distributed channel assignment in cognitive radio (CR) networks. CRs are capable of identifying underutilized licensed bands of the spectrum, allowing their reuse by secondary users without interfering with primary users. In this context, efficient channel assignment is challenging as ideally it must be simple, incur acceptable communication overhead, provide timely response, and be adaptive to accommodate frequent changes in the network. Another ...

Relationship Structures and Semantic Type Assignments of the UMLS Enriched Semantic Network

Science.gov (United States)

Zhang, Li; Halper, Michael; Perl, Yehoshua; Geller, James; Cimino, James J.

2005-01-01

Objective: The Enriched Semantic Network (ESN) was introduced as an extension of the Unified Medical Language System (UMLS) Semantic Network (SN). Its multiple subsumption configuration and concomitant multiple inheritance make the ESN's relationship structures and semantic type assignments different from those of the SN. A technique for deriving the relationship structures of the ESN's semantic types and an automated technique for deriving the ESN's semantic type assignments from those of the SN are presented. Design: The technique to derive the ESN's relationship structures finds all newly inherited relationships in the ESN. All such relationships are audited for semantic validity, and the blocking mechanism is used to block invalid relationships. The mapping technique to derive the ESN's semantic type assignments uses current SN semantic type assignments and preserves nonredundant categorizations, while preventing new redundant categorizations. Results: Among the 426 newly inherited relationships, 326 are deemed valid. Seven blockings are applied to avoid inheritance of the 100 invalid relationships. Sixteen semantic types have different relationship structures in the ESN as compared to those in the SN. The mapping of semantic type assignments from the SN to the ESN avoids the generation of 26,950 redundant categorizations. The resulting ESN contains 138 semantic types, 149 IS-A links, 7,303 relationships, and 1,013,876 semantic type assignments. Conclusion: The ESN's multiple inheritance provides more complete relationship structures than in the SN. The ESN's semantic type assignments avoid the existing redundant categorizations appearing in the SN and prevent new ones that might arise due to multiple parents. Compared to the SN, the ESN provides a more accurate unifying semantic abstraction of the UMLS Metathesaurus. PMID:16049233

Auditing the Assignments of Top-Level Semantic Types in the UMLS Semantic Network to UMLS Concepts.

Science.gov (United States)

He, Zhe; Perl, Yehoshua; Elhanan, Gai; Chen, Yan; Geller, James; Bian, Jiang

2017-11-01

The Unified Medical Language System (UMLS) is an important terminological system. By the policy of its curators, each concept of the UMLS should be assigned the most specific Semantic Types (STs) in the UMLS Semantic Network (SN). Hence, the Semantic Types of most UMLS concepts are assigned at or near the bottom (leaves) of the UMLS Semantic Network. While most ST assignments are correct, some errors do occur. Therefore, Quality Assurance efforts of UMLS curators for ST assignments should concentrate on automatically detected sets of UMLS concepts with higher error rates than random sets. In this paper, we investigate the assignments of top-level semantic types in the UMLS semantic network to concepts, identify potential erroneous assignments, define four categories of errors, and thus provide assistance to curators of the UMLS to avoid these assignments errors. Human experts analyzed samples of concepts assigned 10 of the top-level semantic types and categorized the erroneous ST assignments into these four logical categories. Two thirds of the concepts assigned these 10 top-level semantic types are erroneous. Our results demonstrate that reviewing top-level semantic type assignments to concepts provides an effective way for UMLS quality assurance, comparing to reviewing a random selection of semantic type assignments.

My Favorite Assignment: From the ABC 2010 Annual Convention, Chicago, Illinois

Science.gov (United States)

Whalen, D. Joel

2011-01-01

The seven Favorite Assignments featured in this article were originally presented at the 2010 ABC Annual Convention, Chicago, Illinois. The reader can consider a variety of learning objectives from team building to persuasion, application of electronic media to face-to-face communication, and much more. Some Favorite Assignments take a full…

20 CFR 658.411 - Filing and assignment of JS-related complaints.

Science.gov (United States)

2010-04-01

... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false Filing and assignment of JS-related... Agency Js Complaint System § 658.411 Filing and assignment of JS-related complaints. (a) JS-related... office personnel shall be as follows: (1) All JS-related complaints filed with a local office, and...

42 CFR 424.73 - Prohibition of assignment of claims by providers.

Science.gov (United States)

2010-10-01

... 42 Public Health 3 2010-10-01 2010-10-01 false Prohibition of assignment of claims by providers. 424.73 Section 424.73 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND... and Reassignment of Claims § 424.73 Prohibition of assignment of claims by providers. (a) Basic...

76 FR 42706 - Amendment of Inspector General Operations & Reporting System Audit, Assignment, and Timesheet...

Science.gov (United States)

2011-07-19

... Operations & Reporting System Audit, Assignment, and Timesheet Files (EPA-42) AGENCY: Environmental... (IGOR) System Audit, Assignment, and Timesheet Files (EPA-42) to the Inspector General Enterprise Management System (IGEMS) Audit, Assignment, and Timesheet Modules. DATES: Effective Dates: Persons wishing...

Concurrent Mass Measurement and Laser Spectroscopy for Unambiguous Isomeric State Assignment

Science.gov (United States)

Lascar, Daniel; Babcock, Carla; Henderson, Jack; Pearson, Matt

2017-09-01

Recent work by the TITAN group at TRIUMF on isomeric state mass measurements of odd-A, neutron-rich cadmium nuclei has shown a disconnect between experiment and theory in 127 g , mCd. The spin and parity assignments of the ground and isomeric states are assigned as 3/2+ and 11/2-, respectively, primarily via systematic arguments. Conversely, state of the art shell model and ab initio calculations show a reversal of the states, predicting a ground state of 11/2- and a 3/2+ isomer. Penning Trap Mass Spectrometry (PTMS) can measure the energy separation between the ground state and the isomer without ambiguity but cannot, on its own, comment on the spin and parity. Collinear Laser Spectroscopy (CLS) experiments have been performed on 127Cd and have elegantly demonstrated the existence of both 3/2+ and 11/2- states. What CLS cannot do, on its own, is assign an ordering to those states. If, however, a PTMS and CLS experiment could be performed concurrently using identical beams from the same facility then there exists sufficient information shared between both experiments that a definitive assignment can be made. We present a concept for a new slate of measurements using existing experimental facilities simultaneously, with shared resources, to definitively assign spin and parity for ground and isomeric states in short-lived nuclei.

Incentivized optimal advert assignment via utility decomposition

NARCIS (Netherlands)

Kelly, F.; Key, P.; Walton, N.

2014-01-01

We consider a large-scale Ad-auction where adverts are assigned over a potentially infinite number of searches. We capture the intrinsic asymmetries in information between advertisers, the advert platform and the space of searches: advertisers know and can optimize the average performance of their

9 CFR 355.10 - Assignment of inspectors.

Science.gov (United States)

2010-01-01

... INSPECTION AND CERTIFICATION CERTIFIED PRODUCTS FOR DOGS, CATS, AND OTHER CARNIVORA; INSPECTION... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Assignment of inspectors. 355.10 Section 355.10 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE...

A game theoretic approach to assignment problems

NARCIS (Netherlands)

Klijn, F.

2000-01-01

Game theory deals with the mathematical modeling and analysis of conflict and cooperation in the interaction of multiple decision makers. This thesis adopts two game theoretic methods to analyze a range of assignment problems that arise in various economic situations. The first method has as

Assignments of rights and obligations under a gas sales contract

International Nuclear Information System (INIS)

Kowch, J.R.M.

1996-01-01

A general overview of the principles of assignment in a gas sales contract was presented. Assignment is a process wherein the rights or obligations under a contract are transferred from one of the contracting parties to a third party. It is, in other words, the introduction of a new party to the original contractual relationship. Under the rights and obligations of a gas sales contract, the most important right of the seller is to have its gas taken and to be paid. Likewise, the most important obligation of the buyer is to take the gas and pay for it. An assignment by either party has the potential to alter the original expectations of the parties or the basis of which they committed to the contract in the first place. Prior to deregulation and unbundling initiatives, gas sellers and buyers could enter a 20 year sales contract and deal exclusively with each other over the entire 20 year term. Since deregulation, there are more players, and a higher level of corporate acquisitions, divestitures, rationalizations, and restructuring. Today, there are greater chances than ever before that the original party to a contract may change, or that certain rights and obligations may be assigned to a third party and affect the expectations under the contract

A career exploration assignment for first-year pharmacy students.

Science.gov (United States)

Sholy, Lydia; Zeenny, Rony

2013-11-12

To develop, implement, and assess student-learning outcomes from an assignment designed to expose first-year pharmacy students (P1) to a wide range of pharmacy career pathways. Students enrolled in a required Pharmacy Practice and Ethics course at the Lebanese American University chose 1 pharmacist career to investigate from a suggested list of 28 career pathways. Students completed a literature review on the selected career, interviewed a pharmacist practicing that career path in Lebanon, wrote a paper, and prepared and delivered a summary presentation to their classmates about the career pathway. Students peer evaluated their classmates after each presentation. More than 85% of the students scored ≥70% on the assignment based on their achievement of student learning outcomes. Responses on an anonymous questionnaire showed that more than 94.6% of students were satisfied with the extent to which the course allowed them to meet the established learning outcomes. A career exploration assignment provided pharmacy students with an opportunity to widen their knowledge and understanding of the different career pathways that are available for them.

Target assignment for security officers to K targets (TASK)

International Nuclear Information System (INIS)

Rowland, J.R.; Shelton, K.W.; Stunkel, C.B.

1983-02-01

A probabilistic algorithm is developed to provide an optimal Target Assignment for Security officers to K targets (TASK) using a maximin criterion. Under the assumption of only a limited number (N) of security officers, the TASK computer model determines deployment assignments which maximize the system protection against sabotage by an adversary who may select any link in the system, including the weakest, for the point of attack. Applying the TASK model to a hypothetical nuclear facility containing a nine-level building reveals that aggregate targets covering multiple vital areas should be utilized to reduce the number of possible target assignments to a value equal to or only slightly larger than N. The increased probability that a given aggregate target is covered by one or more security officers offsets the slight decrease in interruption probability due to its occurring earlier in the adversary's path. In brief, the TASK model determines the optimal maximin deployment strategy for limited numbers of security officers and calculates a quantitative measure of the resulting system protection

Evaluation of a Brief Homework Assignment Designed to Reduce Citation Problems

Science.gov (United States)

Schuetze, Pamela

2004-01-01

I evaluated a brief homework assignment designed to reduce citation problems in research-based term papers. Students in 2 developmental psychology classes received a brief presentation and handout defining plagiarism with tips on how to cite sources to avoid plagiarizing. In addition, students in 1 class completed 2 brief homework assignments in…

Integrating Graphing Assignments into a Money and Banking Course Using FRED

Science.gov (United States)

Staveley-O'Carroll, James

2018-01-01

Over the course of one semester, six empirical assignments that utilize FRED are used to introduce students of money and banking courses to the economic analysis required for the conduct of monetary policy. The first five assignments cover the following topics: inflation, bonds and stocks, monetary aggregates, the Taylor rule, and employment.…

A demand assignment control in international business satellite communications network

Science.gov (United States)

Nohara, Mitsuo; Takeuchi, Yoshio; Takahata, Fumio; Hirata, Yasuo

An experimental system is being developed for use in an international business satellite (IBS) communications network based on demand-assignment (DA) and TDMA techniques. This paper discusses its system design, in particular from the viewpoints of a network configuration, a DA control, and a satellite channel-assignment algorithm. A satellite channel configuration is also presented along with a tradeoff study on transmission rate, HPA output power, satellite resource efficiency, service quality, and so on.

Can the surgical checklist reduce the risk of wrong site surgery in orthopaedics? - can the checklist help? Supporting evidence from analysis of a national patient incident reporting system

Directory of Open Access Journals (Sweden)

Cleary Kevin

2011-04-01

Full Text Available Abstract Background Surgical procedures are now very common, with estimates ranging from 4% of the general population having an operation per annum in economically-developing countries; this rising to 8% in economically-developed countries. Whilst these surgical procedures typically result in considerable improvements to health outcomes, it is increasingly appreciated that surgery is a high risk industry. Tools developed in the aviation industry are beginning to be used to minimise the risk of errors in surgery. One such tool is the World Health Organization's (WHO surgery checklist. The National Patient Safety Agency (NPSA manages the largest database of patient safety incidents (PSIs in the world, already having received over three million reports of episodes of care that could or did result in iatrogenic harm. The aim of this study was to estimate how many incidents of wrong site surgery in orthopaedics that have been reported to the NPSA could have been prevented by the WHO surgical checklist. Methods The National Reporting and Learning Service (NRLS database was searched between 1st January 2008- 31st December 2008 to identify all incidents classified as wrong site surgery in orthopaedics. These incidents were broken down into the different types of wrong site surgery. A Likert-scale from 1-5 was used to assess the preventability of these cases if the checklist was used. Results 133/316 (42% incidents satisfied the inclusion criteria. A large proportion of cases, 183/316 were misclassified. Furthermore, there were fewer cases of actual harm [9% (12/133] versus 'near-misses' [121/133 (91%]. Subsequent analysis revealed a smaller proportion of 'near-misses' being prevented by the checklist than the proportion of incidents that resulted in actual harm; 18/121 [14.9% (95% CI 8.5 - 21.2%] versus 10/12 [83.3% (95%CI 62.2 - 104.4%] respectively. Summatively, the checklist could have been prevented 28/133 [21.1% (95%CI 14.1 - 28.0%] patient safety

An analysis of project selection and assignment criteria of Danish tenders in Europe

Directory of Open Access Journals (Sweden)

Jasper Kranker Larsen

2013-12-01

Full Text Available Public construction agencies are one of the largest developers within the Danish construction industry, where such agencies own and develop new public construction projects. Most of these projects are put out in European tender. This study analyses the selection and assignment criteria employed by these agencies in different types of public sector projects. Some of the objectives pursued by the study include the determination of 1/ the selection and assignment criteria mostly used in Danish public tenders 2/ how different types of projects use selection and assignment criteria in the bidding process, and 3/ any significant difference between the use of selection and assignment criteria in Danish public construction projects. The study uses a quantitative research approach where 157 Danish public tender cases were selected from the European Tenders Electronic Daily database between the period: January 2010 to March 2013. Fisher's Exact Test was conducted to determine if there was any significant use of some selection and assignment criteria. The findings of the study showed that invited tenders with pre-qualification and lowest price in 69.8% of the tenders are the most used selection and assignment criteria, with little regard to project type.

Fluidity models in ancient Greece and current practices of sex assignment.

Science.gov (United States)

Chen, Min-Jye; McCann-Crosby, Bonnie; Gunn, Sheila; Georgiadis, Paraskevi; Placencia, Frank; Mann, David; Axelrad, Marni; Karaviti, L P; McCullough, Laurence B

2017-06-01

Disorders of sexual differentiation such as androgen insensitivity and gonadal dysgenesis can involve an intrinsic fluidity at different levels, from the anatomical and biological to the social (gender) that must be considered in the context of social constraints. Sex assignment models based on George Engel's biopsychosocial aspects model of biology accept fluidity of gender as a central concept and therefore help establish expectations within the uncertainty of sex assignment and anticipate potential changes. The biology underlying the fluidity inherent to these disorders should be presented to parents at diagnosis, an approach that the gender medicine field should embrace as good practice. Greek mythology provides many accepted archetypes of change, and the ancient Greek appreciation of metamorphosis can be used as context with these patients. Our goal is to inform expertise and optimal approaches, knowing that this fluidity may eventually necessitate sex reassignment. Physicians should provide sex assignment education based on different components of sexual differentiation, prepare parents for future hormone-triggered changes in their children, and establish a sex-assignment algorithm. Copyright © 2017 Elsevier Inc. All rights reserved.

Edge-assignment and figure-ground segmentation in short-term visual matching.

Science.gov (United States)

Driver, J; Baylis, G C

1996-12-01

Eight experiments examined the role of edge-assignment in a contour matching task. Subjects judged whether the jagged vertical edge of a probe shape matched the jagged edge that divided two adjoining shapes in an immediately preceding figure-ground display. Segmentation factors biased assignment of this dividing edge toward a figural shape on just one of its sides. Subjects were faster and more accurate at matching when the probe edge had a corresponding assignment. The rapid emergence of this effect provides an on-line analog of the long-term memory advantage for figures over grounds which Rubin (1915/1958) reported. The present on-line advantage was found when figures were defined by relative contrast and size, or by symmetry, and could not be explained solely by the automatic drawing of attention toward the location of the figural region. However, deliberate attention to one region of an otherwise ambiguous figure-ground display did produce the advantage. We propose that one-sided assignment of dividing edges may be obligatory in vision.

Fluidity models in ancient Greece and current practices of sex assignment

Science.gov (United States)

Chen, Min-Jye; McCann-Crosby, Bonnie; Gunn, Sheila; Georgiadis, Paraskevi; Placencia, Frank; Mann, David; Axelrad, Marni; Karaviti, L.P; McCullough, Laurence B.

2018-01-01

Disorders of sexual differentiation such as androgen insensitivity and gonadal dysgenesis can involve an intrinsic fluidity at different levels, from the anatomical and biological to the social (gender) that must be considered in the context of social constraints. Sex assignment models based on George Engel’s biopsychosocial aspects model of biology accept fluidity of gender as a central concept and therefore help establish expectations within the uncertainty of sex assignment and anticipate potential changes. The biology underlying the fluidity inherent to these disorders should be presented to parents at diagnosis, an approach that the gender medicine field should embrace as good practice. Greek mythology provides many accepted archetypes of change, and the ancient Greek appreciation of metamorphosis can be used as context with these patients. Our goal is to inform expertise and optimal approaches, knowing that this fluidity may eventually necessitate sex reassignment. Physicians should provide sex assignment education based on different components of sexual differentiation, prepare parents for future hormone-triggered changes in their children, and establish a sex-assignment algorithm. PMID:28478088

Assignment of stock keeping units to parallel undirectional picking

Directory of Open Access Journals (Sweden)

Matthews, Jason

2015-05-01

Full Text Available An order picking system consisting of a number of parallel unidirectional picking lines is investigated. Stock keeping units (SKUs that are grouped by product type into distributions (DBNs are assigned daily to available picking lines. A mathematical programming formulation and its relaxations is presented. A greedy insertion and a greedy phased insertion are further introduced to obtain feasible results within usable computation times for all test cases. The walking distance of the pickers was shown to decrease by about 22 per cent compared with the current assignment approach. However, product handling and operational risk increases.

Distributed Schemes for Crowdsourcing-Based Sensing Task Assignment in Cognitive Radio Networks

Directory of Open Access Journals (Sweden)

Linbo Zhai

2017-01-01

Full Text Available Spectrum sensing is an important issue in cognitive radio networks. The unlicensed users can access the licensed wireless spectrum only when the licensed wireless spectrum is sensed to be idle. Since mobile terminals such as smartphones and tablets are popular among people, spectrum sensing can be assigned to these mobile intelligent terminals, which is called crowdsourcing method. Based on the crowdsourcing method, this paper studies the distributed scheme to assign spectrum sensing task to mobile terminals such as smartphones and tablets. Considering the fact that mobile terminals’ positions may influence the sensing results, a precise sensing effect function is designed for the crowdsourcing-based sensing task assignment. We aim to maximize the sensing effect function and cast this optimization problem to address crowdsensing task assignment in cognitive radio networks. This problem is difficult to be solved because the complexity of this problem increases exponentially with the growth in mobile terminals. To assign crowdsensing task, we propose four distributed algorithms with different transition probabilities and use a Markov chain to analyze the approximation gap of our proposed schemes. Simulation results evaluate the average performance of our proposed algorithms and validate the algorithm’s convergence.

A New Approach to Weapon-Target Assignment in Cooperative Air Combat

Directory of Open Access Journals (Sweden)

Yi-zhe Chang

2017-01-01

Full Text Available A new approach to solving weapon-target assignment (WTA problem is proposed in this paper. Firstly, relative superiority that lays the foundation for assignment is calculated based on the combat power energy of the fighters. Based on the relative superiority, WTA problem is formulated. Afterwards, a hybrid algorithm consisting of improved artificial fish swarm algorithm (AFSA and improved harmony search (HS is introduced and furthermore applied to solve the assignment formulation. Finally, the proposed approach is validated by eight representative benchmark functions and two concrete cooperative air combat examples. The results show that the approach proposed in this paper achieves good performances in solving WTA problem in cooperative air combat.

FISCAL DECENTRALIZATION IN THE DRC: EVIDENCE OFREVENUE ASSIGNMENT

Directory of Open Access Journals (Sweden)

Angelita Kithatu-Kiwekete

2017-07-01

Full Text Available The rationalefor central government to devolve resources for service provisionhas been debated in decentralization literature. Decentralization enhancesdemocracy,encouragesparticipation in local development initiativesandpromotes local political accountability.This discourse has been complemented bythe implementation of fiscal decentralization to increase the ability of sub-nationalgovernment in financing municipal service delivery. Fiscal decentralization hasoften been adopted by African statessince the onset ofthe New PublicManagement erain an effortto improvethe standard ofgovernance. The concernis that African states have taken minimal steps to adopt fiscal devolution thatpromotes revenue assignment which in turn limits sub-nationalgovernments’ability to generate own source revenues.This article examines the revenue assignment function of fiscal decentralization inthe Democratic Republic of Congo(DRCinthelight of decentralizationconcerns that have been raised by civil society, as the country charts its course todemocracy. The article is a desktop study that will consider documents andpoliciesin theDRCon thenational, provincialand locallevel as far asstaterevenue sourcesare concerned. Revenue assignment should enable DRC’sprovinces and local authoritiestogeneratesignificantrevenueindependently.However, post-conflict reconstruction and development efforts in the Great Lakesregion and in the DRC have largely isolated decentralization which wouldotherwise entrench local fiscalautonomy infinancing for local services anddevelopment. The article concludes that revenue generation for local authoritiesandtheprovinces in the DRC is still very centralised by the national government.Thearticleproposes policy recommendations that will be useful for the country toensurethatdecentralization effortsinclude fiscal devolution toenhance thefinancing for local development initiatives.

Generalised Assignment Matrix Methodology in Linear Programming

Science.gov (United States)

Jerome, Lawrence

2012-01-01

Discrete Mathematics instructors and students have long been struggling with various labelling and scanning algorithms for solving many important problems. This paper shows how to solve a wide variety of Discrete Mathematics and OR problems using assignment matrices and linear programming, specifically using Excel Solvers although the same…

Proposed criteria for the evaluation of an address assignment scheme in Botswana

CSIR Research Space (South Africa)

Ditsela, J

2011-06-01

Full Text Available propose criteria for an address assignment scheme in Botswana: a single set of place or area names; different addresses types for urban, rural and farm areas; principles for address numbering assignment; integration of different referencing systems; and a...

Improvement in Student Data Analysis Skills after Out-of-Class Assignments

Directory of Open Access Journals (Sweden)

Kristen Lee Williams Walton

2016-12-01

Full Text Available The ability to understand and interpret data is a critical aspect of scientific thinking.  However, although data analysis is often a focus in biology majors classes, many textbooks for allied health majors classes are primarily content-driven and do not include substantial amounts of experimental data in the form of graphs and figures.  In a lower-division allied health majors microbiology class, students were exposed to data from primary journal articles as take-home assignments and their data analysis skills were assessed in a pre-/posttest format.  Students were given 3 assignments that included data analysis questions.  Assignments ranged from case studies that included a figure from a journal article to reading a short journal article and answering questions about multiple figures or tables.  Data were represented as line or bar graphs, gel photographs, and flow charts.  The pre- and posttest was designed incorporating the same types of figures to assess whether the assignments resulted in any improvement in data analysis skills.  The mean class score showed a small but significant improvement from the pretest to the posttest across three semesters of testing.  Scores on individual questions testing accurate conclusions and predictions improved the most.  This supports the conclusion that a relatively small number of out-of-class assignments through the semester resulted in a significant improvement in data analysis abilities in this population of students.

Model morphing and sequence assignment after molecular replacement

Energy Technology Data Exchange (ETDEWEB)

Terwilliger, Thomas C., E-mail: terwilliger@lanl.gov [Los Alamos National Laboratory, Mail Stop M888, Los Alamos, NM 87545 (United States); Read, Randy J. [University of Cambridge, Cambridge Institute for Medical Research, Cambridge CB2 0XY (United Kingdom); Adams, Paul D. [Lawrence Berkeley National Laboratory, One Cyclotron Road, Bldg 64R0121, Berkeley, CA 94720 (United States); Brunger, Axel T. [Stanford University, 318 Campus Drive West, Stanford, CA 94305 (United States); Afonine, Pavel V. [Lawrence Berkeley National Laboratory, One Cyclotron Road, Bldg 64R0121, Berkeley, CA 94720 (United States); Hung, Li-Wei [Los Alamos National Laboratory, Mail Stop M888, Los Alamos, NM 87545 (United States)

2013-11-01

A procedure for model building is described that combines morphing a model to match a density map, trimming the morphed model and aligning the model to a sequence. A procedure termed ‘morphing’ for improving a model after it has been placed in the crystallographic cell by molecular replacement has recently been developed. Morphing consists of applying a smooth deformation to a model to make it match an electron-density map more closely. Morphing does not change the identities of the residues in the chain, only their coordinates. Consequently, if the true structure differs from the working model by containing different residues, these differences cannot be corrected by morphing. Here, a procedure that helps to address this limitation is described. The goal of the procedure is to obtain a relatively complete model that has accurate main-chain atomic positions and residues that are correctly assigned to the sequence. Residues in a morphed model that do not match the electron-density map are removed. Each segment of the resulting trimmed morphed model is then assigned to the sequence of the molecule using information about the connectivity of the chains from the working model and from connections that can be identified from the electron-density map. The procedure was tested by application to a recently determined structure at a resolution of 3.2 Å and was found to increase the number of correctly identified residues in this structure from the 88 obtained using phenix.resolve sequence assignment alone (Terwilliger, 2003 ▶) to 247 of a possible 359. Additionally, the procedure was tested by application to a series of templates with sequence identities to a target structure ranging between 7 and 36%. The mean fraction of correctly identified residues in these cases was increased from 33% using phenix.resolve sequence assignment to 47% using the current procedure. The procedure is simple to apply and is available in the Phenix software package.

Model morphing and sequence assignment after molecular replacement

International Nuclear Information System (INIS)

Terwilliger, Thomas C.; Read, Randy J.; Adams, Paul D.; Brunger, Axel T.; Afonine, Pavel V.; Hung, Li-Wei

2013-01-01

A procedure for model building is described that combines morphing a model to match a density map, trimming the morphed model and aligning the model to a sequence. A procedure termed ‘morphing’ for improving a model after it has been placed in the crystallographic cell by molecular replacement has recently been developed. Morphing consists of applying a smooth deformation to a model to make it match an electron-density map more closely. Morphing does not change the identities of the residues in the chain, only their coordinates. Consequently, if the true structure differs from the working model by containing different residues, these differences cannot be corrected by morphing. Here, a procedure that helps to address this limitation is described. The goal of the procedure is to obtain a relatively complete model that has accurate main-chain atomic positions and residues that are correctly assigned to the sequence. Residues in a morphed model that do not match the electron-density map are removed. Each segment of the resulting trimmed morphed model is then assigned to the sequence of the molecule using information about the connectivity of the chains from the working model and from connections that can be identified from the electron-density map. The procedure was tested by application to a recently determined structure at a resolution of 3.2 Å and was found to increase the number of correctly identified residues in this structure from the 88 obtained using phenix.resolve sequence assignment alone (Terwilliger, 2003 ▶) to 247 of a possible 359. Additionally, the procedure was tested by application to a series of templates with sequence identities to a target structure ranging between 7 and 36%. The mean fraction of correctly identified residues in these cases was increased from 33% using phenix.resolve sequence assignment to 47% using the current procedure. The procedure is simple to apply and is available in the Phenix software package

Accuracy of administratively-assigned ancestry for diverse populations in an electronic medical record-linked biobank.

Directory of Open Access Journals (Sweden)

Jacob B Hall

Full Text Available Recently, the development of biobanks linked to electronic medical records has presented new opportunities for genetic and epidemiological research. Studies based on these resources, however, present unique challenges, including the accurate assignment of individual-level population ancestry. In this work we examine the accuracy of administratively-assigned race in diverse populations by comparing assigned races to genetically-defined ancestry estimates. Using 220 ancestry informative markers, we generated principal components for patients in our dataset, which were used to cluster patients into groups based on genetic ancestry. Consistent with other studies, we find a strong overall agreement (Kappa  = 0.872 between genetic ancestry and assigned race, with higher rates of agreement for African-descent and European-descent assignments, and reduced agreement for Hispanic, East Asian-descent, and South Asian-descent assignments. These results suggest caution when selecting study samples of non-African and non-European backgrounds when administratively-assigned race from biobanks is used.

ATTRIBUTION OF CONDUCT TO A STATE-THE SUBJECTIVE ELEMENT OF THE INTERNATIONAL RESPONSIBILITY OT THE STATE FOR INTERNATIONALLY WRONGFUL ACTS

Directory of Open Access Journals (Sweden)

FELICIA MAXIM

2012-05-01

Full Text Available In order to establish responsibility of states for internationally wrongful act, two elements are identified. First, the conduct in question must be attributable to the State under international law. Secondly, for responsibility to attach to the act of the State, the conduct must constitute a breach of an international legal obligation in force for that State at that time. For particular conduct to be characterized as an internationally wrongful act, it must first be attributable to the State. The State is a real organized entity, a legal person with full authority to act under international law. But to recognize this is not to deny the elementary fact that the State cannot act of itself. States can act only by and through their agents and representatives. In determining what constitutes an organ of a State for the purposes of responsibility, the internal law and practice of each State are of prime importance. The structure of the State and the functions of its organs are not, in general, governed by international law. It is a matter for each State to decide how its administration is to be structured and which functions are to be assumed by government. But while the State remains free to determine its internal structure and functions through its own law and practice, international law has a distinct role. Conduct is thereby attributed to the State as a subject of international law and not as a subject of internal law. The State as a subject of international law is held responsible for the conduct of all the organs, instrumentalities and officials which form part of its organization and act in that capacity, whether or not they have separate legal personality under its internal law.

Sepsis Definitions: The Search for Gold and What CMS Got Wrong.

Science.gov (United States)

Kalantari, Annahieta; Mallemat, Haney; Weingart, Scott D

2017-08-01

On October 1, 2015, the United States Centers for Medicare and Medicaid Services (CMS) issued a core measure addressing the care of septic patients. These core measures are controversial among healthcare providers. This article will address that there is no gold standard definition for sepsis, severe sepsis or septic shock and the CMS-assigned definitions for severe sepsis and septic shock are premature and inconsistent with evidence-based definitions.

28 CFR 345.35 - Assignments to FPI.

Science.gov (United States)

2010-07-01

..., color, religion, ethnic origin, age, or disability. (b) The SOI ordinarily makes assignments based on... course in pre-industrial training or on-the-job training (as available) before promotion to pay grade four. (2) An inmate who has not successfully completed pre-industrial or on-the-job training remains at...

Imagining wrong: Fictitious contexts mitigate condemnation of harm more than impurity.

Science.gov (United States)

Sabo, John S; Giner-Sorolla, Roger

2017-01-01

Over 5 experiments, we test the fictive pass asymmetry hypothesis. Following observations of ethics and public reactions to media, we propose that fictional contexts, such as reality, imagination, and virtual environments, will mitigate people's moral condemnation of harm violations, more so than purity violations. That is, imagining a purely harmful act is given a "fictive pass," in moral judgment, whereas imagining an abnormal act involving the body is evaluated more negatively because it is seen as more diagnostic of bad character. For Experiment 1, an undergraduate sample (N = 250) evaluated 9 vignettes depicting an agent committing either violations of harm or purity in real life, watching them in films, or imagining them. For Experiments 2 and 3, online participants (N = 375 and N = 321, respectively) evaluated a single vignette depicting an agent committing a violation of harm or purity that either occurred in real life, was imagined, watched in a film, or performed in a video game. Experiment 4 (N = 348) used an analysis of moderated mediation to demonstrate that the perceived wrongness of fictional purity violations is explained both by the extent to which they are seen as a cue to, and a cause of, a poor moral character. Lastly, Experiment 5 (N = 484) validated our manipulations and included the presumption of desire as an additional mediator of the fictive pass asymmetry effects. We discuss implications for moral theories of act and character, anger and disgust, and for media use and regulation. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

Fragment assignment in the cloud with eXpress-D

Science.gov (United States)

2013-01-01

Background Probabilistic assignment of ambiguously mapped fragments produced by high-throughput sequencing experiments has been demonstrated to greatly improve accuracy in the analysis of RNA-Seq and ChIP-Seq, and is an essential step in many other sequence census experiments. A maximum likelihood method using the expectation-maximization (EM) algorithm for optimization is commonly used to solve this problem. However, batch EM-based approaches do not scale well with the size of sequencing datasets, which have been increasing dramatically over the past few years. Thus, current approaches to fragment assignment rely on heuristics or approximations for tractability. Results We present an implementation of a distributed EM solution to the fragment assignment problem using Spark, a data analytics framework that can scale by leveraging compute clusters within datacenters–“the cloud”. We demonstrate that our implementation easily scales to billions of sequenced fragments, while providing the exact maximum likelihood assignment of ambiguous fragments. The accuracy of the method is shown to be an improvement over the most widely used tools available and can be run in a constant amount of time when cluster resources are scaled linearly with the amount of input data. Conclusions The cloud offers one solution for the difficulties faced in the analysis of massive high-thoughput sequencing data, which continue to grow rapidly. Researchers in bioinformatics must follow developments in distributed systems–such as new frameworks like Spark–for ways to port existing methods to the cloud and help them scale to the datasets of the future. Our software, eXpress-D, is freely available at: http://github.com/adarob/express-d. PMID:24314033

Position statement. The right to accept or reject an assignment. American Nurses Association.

Science.gov (United States)

1996-01-01

The American Nurses Association (ANA) believes that nurses should reject assignment that puts patients or themselves in serious, immediate jeopardy. ANA supports the nurses obligation to reject an assignment in these situations even where there is not a specific legal protection for rejecting such an assignment. The professional obligations to the nurse to safeguard clients are grounded in the ethical norms of the profession, the Standards of Clinical Nursing Practice and state nurse practice acts.

A Branch-and-Price algorithm for stable workforce assignments with hierarchical skills

NARCIS (Netherlands)

Firat, M.; Briskorn, D.; Laugier, A.

2016-01-01

This paper deals with assigning hierarchically skilled technicians to jobs by considering preferences. We investigate stability definitions in multi-skill workforce assignments stemming from the notion of blocking pairs as stated in the Marriage model of Gale–Shapley. We propose a Branch-and-Price

Statistical methods of spin assignment in compound nuclear reactions

International Nuclear Information System (INIS)

Mach, H.; Johns, M.W.

1984-01-01

Spin assignment to nuclear levels can be obtained from standard in-beam gamma-ray spectroscopy techniques and in the case of compound nuclear reactions can be complemented by statistical methods. These are based on a correlation pattern between level spin and gamma-ray intensities feeding low-lying levels. Three types of intensity and level spin correlations are found suitable for spin assignment: shapes of the excitation functions, ratio of intensity at two beam energies or populated in two different reactions, and feeding distributions. Various empirical attempts are examined and the range of applicability of these methods as well as the limitations associated with them are given. 12 references

Statistical methods of spin assignment in compound nuclear reactions

International Nuclear Information System (INIS)

Mach, H.; Johns, M.W.

1985-01-01

Spin assignment to nuclear levels can be obtained from standard in-beam gamma-ray spectroscopy techniques and in the case of compound nuclear reactions can be complemented by statistical methods. These are based on a correlation pattern between level spin and gamma-ray intensities feeding low-lying levels. Three types of intensity and level spin correlations are found suitable for spin assignment: shapes of the excitation functions, ratio of intensity at two beam energies or populated in two different reactions, and feeding distributions. Various empirical attempts are examined and the range of applicability of these methods as well as the limitations associated with them are given

Dynamic Passenger Assignment during Disruptions in Railway Systems

NARCIS (Netherlands)

Zhu, Y.; Goverde, R.M.P.

2017-01-01

Passenger-oriented rescheduling problems receive increasing attention. However, the passenger assignment models used for evaluating the rescheduling solutions are usually simplified by many assumptions. To estimate passenger inconvenience more accurately, this paper establishes a dynamic passenger

Exploiting Group Symmetry in Semidefinite Programming Relaxations of the Quadratic Assignment Problem

NARCIS (Netherlands)

de Klerk, E.; Sotirov, R.

2007-01-01

We consider semidefinite programming relaxations of the quadratic assignment problem, and show how to exploit group symmetry in the problem data. Thus we are able to compute the best known lower bounds for several instances of quadratic assignment problems from the problem library: [R.E. Burkard,

Accounting for Sustainability: An Active Learning Assignment

Science.gov (United States)

Gusc, Joanna; van Veen-Dirks, Paula

2017-01-01

Purpose: Sustainability is one of the newer topics in the accounting courses taught in university teaching programs. The active learning assignment as described in this paper was developed for use in an accounting course in an undergraduate program. The aim was to enhance teaching about sustainability within such a course. The purpose of this…

A Comparative Analysis of Pair-work and Individual Assignments In two ELT Grammar Classes

Directory of Open Access Journals (Sweden)

Olcay Sert

2005-10-01

Full Text Available Assignments prepared in pair-work have long been evaluated to be more successful whencompared to individually prepared assignments in many respects in foreign language learningcontexts. However, there is not much research conducted to reveal the advantages of pair-work in preparing assignments and the linguistic characteristics of the finished texts. In this paper, depending upon an experimental study with the first year students in Department of EnglishLanguage Teaching at Hacettepe University, quality of pair-work assignments and the factors affecting the preparation process are discussed and compared to individual assignments. Results indicate a variety of advantages of student collaboration in preparing written work since outputsare far more grammatical, include less spelling mistakes, and indicate a higher level ofgrammatical awareness. Additionally, pair-work helps students build positive interpersonalrelationships and create a high level of academic solidarity and confidence.

Assigned value improves memory of proper names.

Science.gov (United States)

Festini, Sara B; Hartley, Alan A; Tauber, Sarah K; Rhodes, Matthew G

2013-01-01

Names are more difficult to remember than other personal information such as occupations. The current research examined the influence of assigned point value on memory and metamemory judgements for names and occupations to determine whether incentive can improve recall of proper names. In Experiment 1 participants studied face-name and face-occupation pairs assigned 1 or 10 points, made judgements of learning, and were given a cued recall test. High-value names were recalled more often than low-value names. However, recall of occupations was not influenced by value. In Experiment 2 meaningless nonwords were used for both names and occupations. The name difficulty disappeared, and value influenced recall of both names and occupations. Thus value similarly influenced names and occupations when meaningfulness was held constant. In Experiment 3 participants were required to use overt rote rehearsal for all items. Value did not boost recall of high-value names, suggesting that differential processing could not be implemented to improve memory. Thus incentives may improve memory for proper names by motivating people to engage in selective rehearsal and effortful elaborative processing.

Psychology Students' Understanding of the Skill-Based Learning Fostered through University Assignments

Science.gov (United States)

Martini, Tanya S.; Rail, Ashley; Norton, Cole

2015-01-01

We examined first-year psychology majors' (N = 195) beliefs about the relevance of two types of university assignments (individual essay and group wiki) and their connection to the development of career-related skills. Students reported that assignments were only somewhat relevant to their career goals, and relevance ratings were typically…

A method to assign failure rates for piping reliability assessments

International Nuclear Information System (INIS)

Gamble, R.M.; Tagart, S.W. Jr.

1991-01-01

This paper reports on a simplified method that has been developed to assign failure rates that can be used in reliability and risk studies of piping. The method can be applied on a line-by-line basis by identifying line and location specific attributes that can lead to piping unreliability from in-service degradation mechanisms and random events. A survey of service experience for nuclear piping reliability also was performed. The data from this survey provides a basis for identifying in-service failure attributes and assigning failure rates for risk and reliability studies

Waste-aware fluid volume assignment for flow-based microfluidic biochips

DEFF Research Database (Denmark)

Schneider, Alexander Rüdiger; Pop, Paul; Madsen, Jan

2017-01-01

complex Fluidic Units (FUs) such as switches, micropumps, mixers and separators can be constructed. When running a biochemical application on a FBMB, fluid volumes are dispensed from input reservoirs and used by the FUs. Given a biochemical application and a biochip, we are interested in determining...... the fluid volume assignment for each operation of the application, such that the FUs volume requirements are satisfied, while over- and underflow are avoided and the total volume of fluid used is minimized. We propose an algorithm for this fluid assignment problem. Compared to previous work, our method...

Asymmetry in some common assignment algorithms: the dispersion factor solution

OpenAIRE

T de la Barra; B Pérez

1986-01-01

Many common assignment algorithms are based on Dial's original design to determine the paths that trip makers will follow from a given origin to destination centroids. The purpose of this paper is to show that the rules that have to be applied result in two unwanted properties. The first is that trips assigned from an origin centroid i to a destination j can be dramatically different to those resulting from centroid j to centroid i , even if the number of trips is the same and the network is ...

36 CFR 292.22 - Land category assignments.

Science.gov (United States)

2010-07-01

... land. (iv) Commercial land. (2) Not later than August 12, 1994, a map or maps displaying the privately... availability of this map or maps in the local newspapers of record. (b) Changes in land category assignment.../grazing land so long as the intended use or development is consistent with the standards in § 292.23 and...

Transdisciplinary assignments in graduate health education as a model for future collaboration.

Science.gov (United States)

Christie, Catherine; Smith, A Russell; Bednarzyk, Michele

2007-01-01

Transdisciplinary health care continues to be at the forefront of patient treatment in the medical arena, in part due to escalating health care costs, an increasing aging population, and the development of multiple chronic diseases. Gaining the knowledge, experience, and principles associated with transdisciplinary teamwork to successfully prepare for modern-day practice is therefore essential for individuals of various health care professions. This report describes an assignment developed and implemented to facilitate professional interaction between graduate physical therapy, nutrition, and nursing students. The objectives of this assignment were to determine through student evaluation the effects of a transdisciplinary experience on students' understanding of the role of another discipline and students' communication skills across disciplines. When evaluating the assignment, students most often remarked that they developed a greater understanding of the roles of the included disciplines and reported a significant increase in communication skills. However, some students did not concur that this assignment was effective due to the scheduling conflicts and lack of teamwork that can occur during a collaborative project. The students' reports of their experiences in completing the assignment provide valuable insights for implementing and/or updating a preparatory transdisciplinary education component in other settings. Additional research can focus on the challenges faced by the majority of the students venturing into actual health care or "real-world" settings for comparative studies.

Bag-of-features based medical image retrieval via multiple assignment and visual words weighting

KAUST Repository

Wang, Jingyan

2011-11-01

Bag-of-features based approaches have become prominent for image retrieval and image classification tasks in the past decade. Such methods represent an image as a collection of local features, such as image patches and key points with scale invariant feature transform (SIFT) descriptors. To improve the bag-of-features methods, we first model the assignments of local descriptors as contribution functions, and then propose a novel multiple assignment strategy. Assuming the local features can be reconstructed by their neighboring visual words in a vocabulary, reconstruction weights can be solved by quadratic programming. The weights are then used to build contribution functions, resulting in a novel assignment method, called quadratic programming (QP) assignment. We further propose a novel visual word weighting method. The discriminative power of each visual word is analyzed by the sub-similarity function in the bin that corresponds to the visual word. Each sub-similarity function is then treated as a weak classifier. A strong classifier is learned by boosting methods that combine those weak classifiers. The weighting factors of the visual words are learned accordingly. We evaluate the proposed methods on medical image retrieval tasks. The methods are tested on three well-known data sets, i.e., the ImageCLEFmed data set, the 304 CT Set, and the basal-cell carcinoma image set. Experimental results demonstrate that the proposed QP assignment outperforms the traditional nearest neighbor assignment, the multiple assignment, and the soft assignment, whereas the proposed boosting based weighting strategy outperforms the state-of-the-art weighting methods, such as the term frequency weights and the term frequency-inverse document frequency weights. © 2011 IEEE.

Bag-of-features based medical image retrieval via multiple assignment and visual words weighting

KAUST Repository

Wang, Jingyan; Li, Yongping; Zhang, Ying; Wang, Chao; Xie, Honglan; Chen, Guoling; Gao, Xin

2011-01-01

Bag-of-features based approaches have become prominent for image retrieval and image classification tasks in the past decade. Such methods represent an image as a collection of local features, such as image patches and key points with scale invariant feature transform (SIFT) descriptors. To improve the bag-of-features methods, we first model the assignments of local descriptors as contribution functions, and then propose a novel multiple assignment strategy. Assuming the local features can be reconstructed by their neighboring visual words in a vocabulary, reconstruction weights can be solved by quadratic programming. The weights are then used to build contribution functions, resulting in a novel assignment method, called quadratic programming (QP) assignment. We further propose a novel visual word weighting method. The discriminative power of each visual word is analyzed by the sub-similarity function in the bin that corresponds to the visual word. Each sub-similarity function is then treated as a weak classifier. A strong classifier is learned by boosting methods that combine those weak classifiers. The weighting factors of the visual words are learned accordingly. We evaluate the proposed methods on medical image retrieval tasks. The methods are tested on three well-known data sets, i.e., the ImageCLEFmed data set, the 304 CT Set, and the basal-cell carcinoma image set. Experimental results demonstrate that the proposed QP assignment outperforms the traditional nearest neighbor assignment, the multiple assignment, and the soft assignment, whereas the proposed boosting based weighting strategy outperforms the state-of-the-art weighting methods, such as the term frequency weights and the term frequency-inverse document frequency weights. © 2011 IEEE.

Stereospecific assignments of glycine in proteins by stereospecific deuteration and {sup 15}N labeling

Energy Technology Data Exchange (ETDEWEB)

Hansen, A.P.; Curley, R.W. Jr.; Panigot, M.J.; Fesik, S.W. [Ohio State Univ., Columbus, OH (United States)

1994-12-01

Stereospecific assignments are important for accurately determining the three-dimensional structures of proteins through the use of multidimensional NMR techniques. It is especially important to stereospecifically assign the glycine {alpha}-protons in proteins because of the potential for different backbone conformations of this residue. These stereospecific assignments are critical for interpreting the {sup 3}J{sub NH,{alpha}H} coupling constants and NOEs involving the glycine {alpha}-protons that determine the conformation of this part of the protein. However, it is often difficult to unambiguously obtain the stereospecific assignments for glycine residues by using only NOE data. In this poster, we present a method for unambiguous, stereospecific assignment of the {alpha}-protons of glycine residues. This method involves synthesis of stereo-specifically deuterated and {sup 15}N-labeled Gly using a slightly modified procedure originally described by Woodard and coworkers for the stereoselective deuteration of glycine. The stereospecifically deuterated and {sup 15}N-labeled Gy has been incorporated into recombinant proteins expressed in both bacterial systems (FKBP) and mammalian cells (u-PA). Two- and three-dimensional isotope-filtered and isotope-edited NMR experiments were used to obtain the stereospecific assignments of the glycine {alpha}-protons for these proteins.

Final Evaluation of Assignment: Media Literacy. A Report to the Discovery Channel.

Science.gov (United States)

Kubey, Robert; Serafin, Gina Marcello

The Assignment: Media Literacy curriculum is a 6-module media literacy curriculum developed by Renee Hobbs of Babson College and her staff in collaboration with the Discovery Channel. There are three versions of Assignment: Media Literacy, one for elementary school students, one for middle school students, and one for high school students. Close…

DNA barcode data accurately assign higher spider taxa

Directory of Open Access Journals (Sweden)

Jonathan A. Coddington

2016-07-01

Full Text Available The use of unique DNA sequences as a method for taxonomic identification is no longer fundamentally controversial, even though debate continues on the best markers, methods, and technology to use. Although both existing databanks such as GenBank and BOLD, as well as reference taxonomies, are imperfect, in best case scenarios “barcodes” (whether single or multiple, organelle or nuclear, loci clearly are an increasingly fast and inexpensive method of identification, especially as compared to manual identification of unknowns by increasingly rare expert taxonomists. Because most species on Earth are undescribed, a complete reference database at the species level is impractical in the near term. The question therefore arises whether unidentified species can, using DNA barcodes, be accurately assigned to more inclusive groups such as genera and families—taxonomic ranks of putatively monophyletic groups for which the global inventory is more complete and stable. We used a carefully chosen test library of CO1 sequences from 49 families, 313 genera, and 816 species of spiders to assess the accuracy of genus and family-level assignment. We used BLAST queries of each sequence against the entire library and got the top ten hits. The percent sequence identity was reported from these hits (PIdent, range 75–100%. Accurate assignment of higher taxa (PIdent above which errors totaled less than 5% occurred for genera at PIdent values >95 and families at PIdent values ≥ 91, suggesting these as heuristic thresholds for accurate generic and familial identifications in spiders. Accuracy of identification increases with numbers of species/genus and genera/family in the library; above five genera per family and fifteen species per genus all higher taxon assignments were correct. We propose that using percent sequence identity between conventional barcode sequences may be a feasible and reasonably accurate method to identify animals to family/genus. However

Dynamic online peer evaluations to improve group assignments in nursing e-learning environment.

Science.gov (United States)

Adwan, Jehad

2016-06-01

The purpose of this research was to evaluate the use of online peer evaluation forms for online group activities in improving group project outcomes. The investigator developed and used a web-based Google Forms® self and peer evaluation form of 2 group assignments' rubric for junior and senior nursing students. The form covered elements of the assignments including: research activity, analysis of the literature, writing of report, participation in making of presentation, overall contribution to the project, and participation in the weekly group discussions. Items were rated from 1 (did not contribute) to 5 (outstanding contribution) in addition to NA when one activity did not apply. The self and peer evaluation process was conducted twice: once after group assignment 1 and once after group assignment 2. The group assignments final products were done in the form of VoiceThread online presentations that were shared with the rest of the class reflecting the groups' work on a health informatics topic of interest. Data collected as the students completed self and peer evaluations for group assignments 1 and 2. Also, optional comments regarding member performance were collected to add contextual information in addition to ratings. Students received credit for completing the peer evaluations and the grade for the particular assignment was affected by their performance based on peer evaluations of their contributions. Students' peer evaluations showed in a color-coded spreadsheet which enabled the course faculty to view real time results of students' ratings after each assignment. The faculty provided timely and tailored feedback to groups or individuals as needed, using positive feedback and commending high performance while urging struggling individual students and groups to improve lower ratings in specific areas. Comparing evaluations of both assignments, there were statistically significant improvements among all students. The mean scores of the entire sample were

Modelling the Preferences of Students for Alternative Assignment Designs Using the Discrete Choice Experiment Methodology

Directory of Open Access Journals (Sweden)

Brendan Kennelly

2014-11-01

Full Text Available This paper outlines how a discrete choice experiment (DCE can be used to learn more about how students are willing to trade off various features of assignments such as the nature and timing of feedback and the method used to submit assignments. A DCE identifies plausible levels of the key attributes of a good or service and then presents the respondent with alternative bundles of these attributes and their levels and asks the respondent to choose between particular bundles. We report results from a DCE we conducted with undergraduate business students regarding their preferences for assignment systems. We find that the most important features of assignments are how relevant the assignments are for exam preparation and the nature of the feedback that students receive. We also find that students generally prefer online to paper assignments. We argue that the DCE approach has a lot of potential in education research.

A Review on Eigenstructure Assignment Methods and Orthogonal Eigenstructure Control of Structural Vibrations

Directory of Open Access Journals (Sweden)

Mohammad Rastgaar

2009-01-01

Full Text Available This paper provides a state-of-the-art review of eigenstructure assignment methods for vibration cancellation. Eigenstructure assignment techniques have been widely used during the past three decades for vibration suppression in structures, especially in large space structures. These methods work similar to mode localization in which global vibrations are managed such that they remain localized within the structure. Such localization would help reducing vibrations more effectively than other methods of vibration cancellation, by virtue of confining the vibrations close to the source of disturbance. The common objective of different methods of eigenstructure assignment is to provide controller design freedom beyond pole placement, and define appropriate shapes for the eigenvectors of the systems. These methods; however, offer a large and complex design space of options that can often overwhelm the control designer. Recent developments in orthogonal eigenstructure control offers a significant simplification of the design task while allowing some experience-based design freedom. The majority of the papers from the past three decades in structural vibration cancellation using eigenstructure assignment methods are reviewed, along with recent studies that introduce new developments in eigenstructure assignment techniques.

De novo protein structure generation from incomplete chemical shift assignments

Energy Technology Data Exchange (ETDEWEB)

Shen Yang [National Institutes of Health, Laboratory of Chemical Physics, National Institute of Diabetes and Digestive and Kidney Diseases (United States); Vernon, Robert; Baker, David [University of Washington, Department of Biochemistry and Howard Hughes Medical Institute (United States); Bax, Ad [National Institutes of Health, Laboratory of Chemical Physics, National Institute of Diabetes and Digestive and Kidney Diseases (United States)], E-mail: bax@nih.gov

2009-02-15

NMR chemical shifts provide important local structural information for proteins. Consistent structure generation from NMR chemical shift data has recently become feasible for proteins with sizes of up to 130 residues, and such structures are of a quality comparable to those obtained with the standard NMR protocol. This study investigates the influence of the completeness of chemical shift assignments on structures generated from chemical shifts. The Chemical-Shift-Rosetta (CS-Rosetta) protocol was used for de novo protein structure generation with various degrees of completeness of the chemical shift assignment, simulated by omission of entries in the experimental chemical shift data previously used for the initial demonstration of the CS-Rosetta approach. In addition, a new CS-Rosetta protocol is described that improves robustness of the method for proteins with missing or erroneous NMR chemical shift input data. This strategy, which uses traditional Rosetta for pre-filtering of the fragment selection process, is demonstrated for two paramagnetic proteins and also for two proteins with solid-state NMR chemical shift assignments.

Performance evaluation of distributed wavelength assignment in WDM optical networks

Science.gov (United States)

Hashiguchi, Tomohiro; Wang, Xi; Morikawa, Hiroyuki; Aoyama, Tomonori

2004-04-01

In WDM wavelength routed networks, prior to a data transfer, a call setup procedure is required to reserve a wavelength path between the source-destination node pairs. A distributed approach to a connection setup can achieve a very high speed, while improving the reliability and reducing the implementation cost of the networks. However, along with many advantages, several major challenges have been posed by the distributed scheme in how the management and allocation of wavelength could be efficiently carried out. In this thesis, we apply a distributed wavelength assignment algorithm named priority based wavelength assignment (PWA) that was originally proposed for the use in burst switched optical networks to the problem of reserving wavelengths of path reservation protocols in the distributed control optical networks. Instead of assigning wavelengths randomly, this approach lets each node select the "safest" wavelengths based on the information of wavelength utilization history, thus unnecessary future contention is prevented. The simulation results presented in this paper show that the proposed protocol can enhance the performance of the system without introducing any apparent drawbacks.

Efficient Stereospecific Hβ2/3 NMR Assignment Strategy for Mid-Size Proteins

Directory of Open Access Journals (Sweden)

Alexandra Born

2018-06-01

Full Text Available We present a strategy for stereospecific NMR assignment of Hβ2 and Hβ3 protons in mid-size proteins (~150 residues. For such proteins, resonance overlap in standard experiments is severe, thereby preventing unambiguous assignment of a large fraction of β-methylenes. To alleviate this limitation, assignment experiments may be run in high static fields, where higher decoupling power is required. Three-bond Hα–Hβ J-couplings (3JHα–Hβ are critical for stereospecific assignments of β-methylene protons, and for determining rotameric χ1 states. Therefore, we modified a pulse sequence designed to measure accurate 3JHα–Hβ couplings such that probe heating was reduced, while the decoupling performance was improved. To further increase the resolution, we applied non-uniform sampling (NUS schemes in the indirect 1H and 13C dimensions. The approach was applied to two medium-sized proteins, odorant binding protein 22 (OBP22; 14.4 kDa and Pin1 (18.2 kDa, at 900 MHz polarizing fields. The coupling values obtained from NUS and linear sampling were extremely well correlated. However, NUS decreased the overlap of Hβ2/3 protons, thus supplying a higher yield of extracted 3JHα-Hβ coupling values when compared with linear sampling. A similar effect could be achieved with linear prediction applied to the linearly sampled data prior to the Fourier transformation. Finally, we used 3JHα–Hβ couplings from Pin1 in combination with either conventional or exact nuclear Overhauser enhancement (eNOE restraints to determine the stereospecific assignments of β-methylene protons. The use of eNOEs further increased the fraction of unambiguously assigned resonances when compared with procedures using conventional NOEs.

Scalable Task Assignment for Heterogeneous Multi-Robot Teams

Directory of Open Access Journals (Sweden)

Paula García

2013-02-01

Full Text Available This work deals with the development of a dynamic task assignment strategy for heterogeneous multi-robot teams in typical real world scenarios. The strategy must be efficiently scalable to support problems of increasing complexity with minimum designer intervention. To this end, we have selected a very simple auction-based strategy, which has been implemented and analysed in a multi-robot cleaning problem that requires strong coordination and dynamic complex subtask organization. We will show that the selection of a simple auction strategy provides a linear computational cost increase with the number of robots that make up the team and allows the solving of highly complex assignment problems in dynamic conditions by means of a hierarchical sub-auction policy. To coordinate and control the team, a layered behaviour-based architecture has been applied that allows the reusing of the auction-based strategy to achieve different coordination levels.

P-wave assignment of 232Th neutron resonances

International Nuclear Information System (INIS)

Corvi, F.; Pasquariello, G.; Veen, T. van der

1978-01-01

A method of p-wave assignment which exploits the parity dependence of the primary capture γ-ray spectrum was applied to the 232 Th resonance. The yield of capture γ-rays above 4.4 MeV from a 6 mm thick metallic thorium disk was measured in the neutron energy range 20-2200 eV and compared to a similar run with γ-rays in the range 3.7 - 4.4 MeV. A total of 58 resonances showing an enhancement of the high energy γ-ray yield were assigned as p-waves. Assuming that their reduced neutron widths follow a Porter-Thomas distribution, their average value and then the p-wave strength function S 1 were estimated with a maximum likelihood method. The results are: average neutron width=3.4(+0.8 or -0.6)meV; S 1 = 2.0 (+0.5 or -0.4).10 -4

Modeling multiple visual words assignment for bag-of-features based medical image retrieval

KAUST Repository

Wang, Jim Jing-Yan

2012-01-01

In this paper, we investigate the bag-of-features based medical image retrieval methods, which represent an image as a collection of local features, such as image patch and key points with SIFT descriptor. To improve the bag-of-features method, we first model the assignment of local descriptor as contribution functions, and then propose a new multiple assignment strategy. By assuming the local feature can be reconstructed by its neighboring visual words in vocabulary, we solve the reconstruction weights as a QP problem and then use the solved weights as contribution functions, which results in a new assignment method called the QP assignment. We carry our experiments on ImageCLEFmed datasets. Experiments\\' results show that our proposed method exceeds the performances of traditional solutions and works well for the bag-of-features based medical image retrieval tasks.

Modeling multiple visual words assignment for bag-of-features based medical image retrieval

KAUST Repository

Wang, Jim Jing-Yan; Almasri, Islam

2012-01-01

In this paper, we investigate the bag-of-features based medical image retrieval methods, which represent an image as a collection of local features, such as image patch and key points with SIFT descriptor. To improve the bag-of-features method, we first model the assignment of local descriptor as contribution functions, and then propose a new multiple assignment strategy. By assuming the local feature can be reconstructed by its neighboring visual words in vocabulary, we solve the reconstruction weights as a QP problem and then use the solved weights as contribution functions, which results in a new assignment method called the QP assignment. We carry our experiments on ImageCLEFmed datasets. Experiments' results show that our proposed method exceeds the performances of traditional solutions and works well for the bag-of-features based medical image retrieval tasks.

Characterizing Sailor and Command Enlisted Placement and Assignment Preferences

National Research Council Canada - National Science Library

Butler, Virginia

2002-01-01

.... DON currently matches sailors to billets using a labor-intensive detailing process. With evolving information technology, the assignment process could be accomplished using intelligent agents and web-based markets...

Symmetric Logic Synthesis with Phase Assignment

OpenAIRE

Benschop, N. F.

2001-01-01

Decomposition of any Boolean Function BF_n of n binary inputs into an optimal inverter coupled network of Symmetric Boolean functions SF_k (k \\leq n) is described. Each SF component is implemented by Threshold Logic Cells, forming a complete and compact T-Cell Library. Optimal phase assignment of input polarities maximizes local symmetries. The "rank spectrum" is a new BF_n description independent of input ordering, obtained by mapping its minterms onto an othogonal n \\times n grid of (transi...

Stereospecific assignment of the asparagine and glutamine sidechain amide protons in proteins from chemical shift analysis

Energy Technology Data Exchange (ETDEWEB)

Harsch, Tobias; Schneider, Philipp; Kieninger, Bärbel; Donaubauer, Harald; Kalbitzer, Hans Robert, E-mail: hans-robert.kalbitzer@biologie.uni-regensburg.de [University of Regensburg, Institute of Biophysics and Physical Biochemistry and Centre of Magnetic Resonance in Chemistry and Biomedicine (Germany)

2017-02-15

Side chain amide protons of asparagine and glutamine residues in random-coil peptides are characterized by large chemical shift differences and can be stereospecifically assigned on the basis of their chemical shift values only. The bimodal chemical shift distributions stored in the biological magnetic resonance data bank (BMRB) do not allow such an assignment. However, an analysis of the BMRB shows, that a substantial part of all stored stereospecific assignments is not correct. We show here that in most cases stereospecific assignment can also be done for folded proteins using an unbiased artificial chemical shift data base (UACSB). For a separation of the chemical shifts of the two amide resonance lines with differences ≥0.40 ppm for asparagine and differences ≥0.42 ppm for glutamine, the downfield shifted resonance lines can be assigned to H{sup δ21} and H{sup ε21}, respectively, at a confidence level >95%. A classifier derived from UASCB can also be used to correct the BMRB data. The program tool AssignmentChecker implemented in AUREMOL calculates the Bayesian probability for a given stereospecific assignment and automatically corrects the assignments for a given list of chemical shifts.

An Ultimatum Game Approach to Billet Assignments

Science.gov (United States)

2015-09-01

time for reviewing instructions, searching existing data sources, gathering and maintaining the data needed , and completing and reviewing this...treatments are needed for this investigation. To conserve the subject pool and meet the budget, we elected to pursue treatments that covered salient...across billets can be partially offset through compensating wages ( hedonic wages) and/or the potential of future superior assignments. In the

A 62-year-old woman with skin cancer who experienced wrong-site surgery: review of medical error.

Science.gov (United States)

Gallagher, Thomas H

2009-08-12

After a life-threatening complication of an injection for neck pain several years ago, Ms W experienced a wrong-site surgery to remove a squamous cell lesion from her nose, followed by pain, distress, and shaken trust in clinicians. Her experience highlights the challenges of communicating with patients after errors. Harmful medical errors occur relatively frequently. Gaps exist between patients' expectations for disclosure and apology and physicians' ability to deliver disclosures well. This discrepancy reflects clinicians' fear of litigation, concern that disclosure might harm patients, and lack of confidence in disclosure skills. Many institutions are developing disclosure programs, and some are reporting success in coupling disclosures with early offers of compensation to patients. However, much has yet to be learned about effective disclosure strategies. Important future developments include increased emphasis on institutions' responsibility for disclosure, involving trainees and other team members in disclosure, and strengthening the relationship between disclosure and quality improvement.

Mining Staff Assignment Rules from Event-Based Data

NARCIS (Netherlands)

Ly, Linh Thao; Rinderle, Stefanie; Dadam, Peter; Reichert, Manfred; Bussler, Christoph J.; Haller, Armin

2006-01-01

Process mining offers methods and techniques for capturing process behaviour from log data of past process executions. Although many promising approaches on mining the control flow have been published, no attempt has been made to mine the staff assignment situation of business processes. In this

77 FR 8174 - EPAAR Prescription for Work Assignments

Science.gov (United States)

2012-02-14

... because it does not affect the level of protection provided to human health or the environment. This rulemaking does not involve human health or environmental affects. K. Congressional Review Act The... Prescription for Work Assignments AGENCY: Environmental Protection Agency (EPA). ACTION: Final rule. SUMMARY...

Design of an adaptive pole assignment controller for steam generators and its experimental study

International Nuclear Information System (INIS)

Na, Man Gyun; No, Hee Cheon

1992-01-01

An adaptive observer is designed that both parameters and state variables of the steam generator are estimated simultaneously. A pole assignment controller is derived on the basis of the adaptive observer. The characteristics of the overall closed-loop control system can be expressed in terms of its poles, assigned poles. The troublesome tuning procedure of the P-I controller is reduced to the determination of the desired poles only. The proposed algorithm is compared with the conventional P-I controller through numerical simulation. Also, the adaptive pole assignment controller is studied experimentally by implementing it to the mock-up of the nuclear steam generator. The adaptive pole assignment controller shows better responses than the P-l controller does. (Author)

Minimum Interference Channel Assignment Algorithm for Multicast in a Wireless Mesh Network

Directory of Open Access Journals (Sweden)

Sangil Choi

2016-12-01

Full Text Available Wireless mesh networks (WMNs have been considered as one of the key technologies for the configuration of wireless machines since they emerged. In a WMN, wireless routers provide multi-hop wireless connectivity between hosts in the network and also allow them to access the Internet via gateway devices. Wireless routers are typically equipped with multiple radios operating on different channels to increase network throughput. Multicast is a form of communication that delivers data from a source to a set of destinations simultaneously. It is used in a number of applications, such as distributed games, distance education, and video conferencing. In this study, we address a channel assignment problem for multicast in multi-radio multi-channel WMNs. In a multi-radio multi-channel WMN, two nearby nodes will interfere with each other and cause a throughput decrease when they transmit on the same channel. Thus, an important goal for multicast channel assignment is to reduce the interference among networked devices. We have developed a minimum interference channel assignment (MICA algorithm for multicast that accurately models the interference relationship between pairs of multicast tree nodes using the concept of the interference factor and assigns channels to tree nodes to minimize interference within the multicast tree. Simulation results show that MICA achieves higher throughput and lower end-to-end packet delay compared with an existing channel assignment algorithm named multi-channel multicast (MCM. In addition, MICA achieves much lower throughput variation among the destination nodes than MCM.

The use of writing assignments to help students synthesize content in upper-level undergraduate biology courses.

Science.gov (United States)

Sparks-Thissen, Rebecca L

2017-02-01

Biology education is undergoing a transformation toward a more student-centered, inquiry-driven classroom. Many educators have designed engaging assignments that are designed to help undergraduate students gain exposure to the scientific process and data analysis. One of these types of assignments is use of a grant proposal assignment. Many instructors have used these assignments in lecture-based courses to help students process information in the literature and apply that information to a novel problem such as design of an antiviral drug or a vaccine. These assignments have been helpful in engaging students in the scientific process in the absence of an inquiry-driven laboratory. This commentary discusses the application of these grant proposal writing assignments to undergraduate biology courses. © FEMS 2017. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

[Rapid assessment of critical quality attributes of Chinese materia medica (II): strategy of NIR assignment].

Science.gov (United States)

Pei, Yan-Ling; Wu, Zhi-Sheng; Shi, Xin-Yuan; Zhou, Lu-Wei; Qiao, Yan-Jiang

2014-09-01

The present paper firstly reviewed the research progress and main methods of NIR spectral assignment coupled with our research results. Principal component analysis was focused on characteristic signal extraction to reflect spectral differences. Partial least squares method was concerned with variable selection to discover characteristic absorption band. Two-dimensional correlation spectroscopy was mainly adopted for spectral assignment. Autocorrelation peaks were obtained from spectral changes, which were disturbed by external factors, such as concentration, temperature and pressure. Density functional theory was used to calculate energy from substance structure to establish the relationship between molecular energy and spectra change. Based on the above reviewed method, taking a NIR spectral assignment of chlorogenic acid as example, a reliable spectral assignment for critical quality attributes of Chinese materia medica (CMM) was established using deuterium technology and spectral variable selection. The result demonstrated the assignment consistency according to spectral features of different concentrations of chlorogenic acid and variable selection region of online NIR model in extract process. Although spectral assignment was initial using an active pharmaceutical ingredient, it is meaningful to look forward to the futurity of the complex components in CMM. Therefore, it provided methodology for NIR spectral assignment of critical quality attributes in CMM.

A branch-and-cut algorithm for the Time Window Assignment Vehicle Routing Problem

NARCIS (Netherlands)

K. Dalmeijer (Kevin); R. Spliet (Remy)

2016-01-01

textabstractThis paper presents a branch-and-cut algorithm for the Time Window Assignment Vehicle Routing Problem (TWAVRP), the problem of assigning time windows for delivery before demand volume becomes known. A novel set of valid inequalities, the precedence inequalities, is introduced and

Persuasive texts for prompting action: Agency assignment in HPV vaccination reminders.

Science.gov (United States)

McGlone, Matthew S; Stephens, Keri K; Rodriguez, Serena A; Fernandez, Maria E

2017-08-03

Vaccination reminders must both inform and persuade, and text messages designed for this purpose must do so in 160 characters or less. We tested a strategy for improving the impact of HPV vaccination text message reminders through strategic wording. In an experiment conducted in community settings, 167 Spanish-speaking Latina mothers reviewed text message reminders that assigned the cause or "agency" for HPV transmission to their daughters or the virus, and assigned protection agency to the mothers or the vaccine. Reminder messages framing transmission as an action of the virus prompted mothers to perceive the threat as more severe than messages describing their daughters as the cause. Assigning transmission agency to the virus also held a persuasive advantage in boosting mothers' intentions to seek vaccination, particularly when the message cast mothers as agents of protection rather than the vaccine. Copyright © 2017 Elsevier Ltd. All rights reserved.

33 CFR 5.33 - Training, examination, and assignment.

Science.gov (United States)

2010-07-01

... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Training, examination, and... GENERAL COAST GUARD AUXILIARY § 5.33 Training, examination, and assignment. The Commandant will prescribe the type of training, qualifications and examinations required before a member of the Auxiliary shall...

Parental knowledge of child development and the assignment of tractor work to children.

Science.gov (United States)

Pickett, William; Marlenga, Barbara; Berg, Richard L

2003-07-01

Many childhood farm tractor injuries occur during the performance of work that was assigned by parents, and some tractor work is beyond the developmental capabilities of children. This has been highlighted recently by a policy statement authored by the American Academy of Pediatrics. The objective of this study was 1) to assess child development knowledge of farm parents who received a new resource, the North American Guidelines for Children's Agricultural Tasks (NAGCAT), and 2) to determine whether this knowledge was associated with use of NAGCAT in the assignment of tractor jobs and with compliance with 2 aspects of the NAGCAT tractor guideline. Secondary analysis of data collected during a randomized controlled trial that involved 450 farms in the United States and Canada was conducted. Variables assessed included 1) parental knowledge of child development across several age groups and 3 domains of child development (physical, cognitive, and psychosocial), 2) documentation of the most common tractor jobs assigned to each child, and 3) a report of whether NAGCAT was used in assigning these tractor jobs. High parental knowledge of child development was associated with enhanced use of NAGCAT and fewer violations when assigning tractor work to children. However, even in the presence of high knowledge, some farm parents still assigned to their children work that was in violation of NAGCAT. Educational interventions by themselves are not sufficient to remove many farm children from known occupational hazards. These findings are discussed in light of the recent policy statement on agricultural injuries from the American Academy of Pediatrics.

Contextual effects on perceived contrast: figure-ground assignment and orientation contrast.

Science.gov (United States)

Self, Matthew W; Mookhoek, Aart; Tjalma, Nienke; Roelfsema, Pieter R

2015-02-02

Figure-ground segregation is an important step in the path leading to object recognition. The visual system segregates objects ('figures') in the visual scene from their backgrounds ('ground'). Electrophysiological studies in awake-behaving monkeys have demonstrated that neurons in early visual areas increase their firing rate when responding to a figure compared to responding to the background. We hypothesized that similar changes in neural firing would take place in early visual areas of the human visual system, leading to changes in the perception of low-level visual features. In this study, we investigated whether contrast perception is affected by figure-ground assignment using stimuli similar to those in the electrophysiological studies in monkeys. We measured contrast discrimination thresholds and perceived contrast for Gabor probes placed on figures or the background and found that the perceived contrast of the probe was increased when it was placed on a figure. Furthermore, we tested how this effect compared with the well-known effect of orientation contrast on perceived contrast. We found that figure-ground assignment and orientation contrast produced changes in perceived contrast of a similar magnitude, and that they interacted. Our results demonstrate that figure-ground assignment influences perceived contrast, consistent with an effect of figure-ground assignment on activity in early visual areas of the human visual system. © 2015 ARVO.

Protein secondary structure: category assignment and predictability

DEFF Research Database (Denmark)

Andersen, Claus A.; Bohr, Henrik; Brunak, Søren

2001-01-01

In the last decade, the prediction of protein secondary structure has been optimized using essentially one and the same assignment scheme known as DSSP. We present here a different scheme, which is more predictable. This scheme predicts directly the hydrogen bonds, which stabilize the secondary......-forward neural network with one hidden layer on a data set identical to the one used in earlier work....

A Qualitative Analysis of the Turkish Gendarmerie Assignment Process

National Research Council Canada - National Science Library

Soylemez, Kadir

2005-01-01

...; this number increases to 43 million (65% of the population) in the summer months. This study is an organizational analysis of the current assignment process of the Turkish General Command of the Gendarmerie...

Asset Mapping: A Course Assignment and Community Assessment

Science.gov (United States)

Crozier, Mary; Melchior, Florence

2013-01-01

Asset mapping is a relatively new data collection strategy to identify services, staff capacity, programs, resources, values, and other protective factors in a geographic area that can be juxtaposed to risk factors when initiating community planning. A substance abuse prevention course for undergraduates added an assignment of assessing community…

Linear Optimization of Frequency Spectrum Assignments Across System

Science.gov (United States)

2016-03-01

selection tools, frequency allocation, transmission optimization, electromagnetic maneuver warfare, electronic protection, assignment model 15. NUMBER ...Characteristics Modeled ...............................................................29 Table 10.   Antenna Systems Modeled , Number of Systems and...surveillance EW early warning GAMS general algebraic modeling system GHz gigahertz IDE integrated development environment ILP integer linear program

7 CFR 1425.24 - OMB control number assigned pursuant to Paperwork Reduction Act.

Science.gov (United States)

2010-01-01

...) COMMODITY CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS COOPERATIVE MARKETING ASSOCIATIONS § 1425.24 OMB control number assigned pursuant to Paperwork Reduction Act. The... Office of Management and Budget (OMB) under the provisions of 44 U.S.C. Chapter 35 and have been assigned...

28 CFR 0.196 - Procedures for resolving disagreements concerning mail or case assignments.

Science.gov (United States)

2010-07-01

... concerning mail or case assignments. 0.196 Section 0.196 Judicial Administration DEPARTMENT OF JUSTICE ORGANIZATION OF THE DEPARTMENT OF JUSTICE Jurisdictional Disagreements § 0.196 Procedures for resolving... assigned, the disagreement, together with a statement of the view of the unit or units involved, shall be...

Joint Channel Assignment and Routing in Multiradio Multichannel Wireless Mesh Networks: Design Considerations and Approaches

Directory of Open Access Journals (Sweden)

Omar M. Zakaria

2016-01-01

Full Text Available Multiradio wireless mesh network is a promising architecture that improves the network capacity by exploiting multiple radio channels concurrently. Channel assignment and routing are underlying challenges in multiradio architectures since both determine the traffic distribution over links and channels. The interdependency between channel assignments and routing promotes toward the joint solutions for efficient configurations. This paper presents an in-depth review of the joint approaches of channel assignment and routing in multiradio wireless mesh networks. First, the key design issues, modeling, and approaches are identified and discussed. Second, existing algorithms for joint channel assignment and routing are presented and classified based on the channel assignment types. Furthermore, the set of reconfiguration algorithms to adapt the network traffic dynamics is also discussed. Finally, the paper presents some multiradio practical implementations and test-beds and points out the future research directions.

Prediction and Assignment of Function for a Divergent N-succinyl Amino Acid Racemase

Energy Technology Data Exchange (ETDEWEB)

Song,L.; Kalyanaraman, C.; Fedorov, A.; Fedorov, E.; Glasner, M.; Brown, S.; Imker, H.; Babbitt, P.; Almo, S.; et al.

2007-01-01

The protein databases contain many proteins with unknown function. A computational approach for predicting ligand specificity that requires only the sequence of the unknown protein would be valuable for directing experiment-based assignment of function. We focused on a family of unknown proteins in the mechanistically diverse enolase superfamily and used two approaches to assign function: (i) enzymatic assays using libraries of potential substrates, and (ii) in silico docking of the same libraries using a homology model based on the most similar (35% sequence identity) characterized protein. The results matched closely; an experimentally determined structure confirmed the predicted structure of the substrate-liganded complex. We assigned the N-succinyl arginine/lysine racemase function to the family, correcting the annotation (L-Ala-D/L-Glu epimerase) based on the function of the most similar characterized homolog. These studies establish that ligand docking to a homology model can facilitate functional assignment of unknown proteins by restricting the identities of the possible substrates that must be experimentally tested.

A Multi-Objective Decision Support Model for the Turkish Armed Forces Personnel Assignment System

National Research Council Canada - National Science Library

Cimen, Zubeyir

2001-01-01

.... TAF wants to obtain maximum utilization of its personnel by assigning the right person to the right job at the right time, To accomplish this task, decision-makers and personnel assignment staff...

New assignment of 14N NQR spectral lines for tetrazoles derivatives

Science.gov (United States)

Mamadazizov, Sultonazar; Shelyapina, Marina G.; Kupriyanova, Galina S.; Mozzhukhin, George V.

2018-04-01

In recent years, considerable interest has been shown in the study of tetrazole derivatives, which attract attention as highly nitrogenous compounds for use as an isosteric substitutes for various functional groups that leads to creation of novel biologically active substances. NQR techniques, being sensitive to the local environment of 14N nuclei, provide great opportunities to study these new substances. To make investigation of complex compounds containing tetrazoles derivatives easier and more reliable a correctly assigned 14N NQR spectra of tetrazoles are required. Here we report on the results of our DFT B3LYP calculations of 14N NQR spectral parameters (quadrupole coupling constant Qcc and the asymmetry parameter of the electric field gradient η) for tetrazole, 5-aminotetrazole and 5-aminotetrazole monohydrate. It has been found that the commonly accepted assignment of the 14N NQR spectral lines for these molecules is incorrect. A new assignment for these molecules is proposed.

Evaluation of Dynamic Channel and Power Assignment for Cognitive Networks

Energy Technology Data Exchange (ETDEWEB)

Syed A. Ahmad; Umesh Shukla; Ryan E. Irwin; Luiz A. DaSilva; Allen B. MacKenzie

2011-03-01

In this paper, we develop a unifying optimization formulation to describe the Dynamic Channel and Power Assignment (DCPA) problem and evaluation method for comparing DCPA algorithms. DCPA refers to the allocation of transmit power and frequency channels to links in a cognitive network so as to maximize the total number of feasible links while minimizing the aggregate transmit power. We apply our evaluation method to five algorithms representative of DCPA used in literature. This comparison illustrates the tradeoffs between control modes (centralized versus distributed) and channel/power assignment techniques. We estimate the complexity of each algorithm. Through simulations, we evaluate the effectiveness of the algorithms in achieving feasible link allocations in the network, as well as their power efficiency. Our results indicate that, when few channels are available, the effectiveness of all algorithms is comparable and thus the one with smallest complexity should be selected. The Least Interfering Channel and Iterative Power Assignment (LICIPA) algorithm does not require cross-link gain information, has the overall lowest run time, and highest feasibility ratio of all the distributed algorithms; however, this comes at a cost of higher average power per link.

Narrative Acts: Telling Tales of Life and Love with the Wrong Gender

Directory of Open Access Journals (Sweden)

James Valentine

2008-05-01

Full Text Available This presentation provides an illustration of performative social science through the world's first project to focus on multi-media storytelling with a nationwide LGBT community for public representation and museum archiving. Where voices are unheard, hidden or suppressed, the images and representations of a community may be stereotyped and discriminatory, constructed about the community by those on the outside. LGBT (lesbian, gay, bisexual and transgender people have experienced social exclusion and marginalisation, and their stories have been neglected or distorted. Their lives and loves have been characterised as wrong: mistaken in medical or moral terms. OurStory Scotland was established to research, record and celebrate the history and experiences of the LGBT community through their own words. Our approach combines action research and performative social science: it is participatory and emancipatory, developing the knowledge of a community through various modes of storytelling performance. This presentation reviews storytelling methods and themes, that have relevance for marginalised communities where disclosure may be problematic. The narrative acts that make up our stories range from one-liners, through written episodes, to oral history recordings, stories shared in group storytelling and narrative exchange, tales told with and through images, "text out" visual displays, "supporting stars" mapping support as an alternative to the conventional family tree, dramatisation and ceilidh performance. The stories challenge fixed and stereotyped identities, and reveal the centrality of storytelling to leading our lives. They also illustrate the rewards of performative action social research, both for a community researching itself and for dissemination more widely. URN: urn:nbn:de:0114-fqs0802491

Application of Neutrosophic Set Theory in Generalized Assignment Problem

Directory of Open Access Journals (Sweden)

Supriya Kar

2015-09-01

Full Text Available This paper presents the application of Neutrosophic Set Theory (NST in solving Generalized Assignment Problem (GAP. GAP has been solved earlier under fuzzy environment. NST is a generalization of the concept of classical set, fuzzy set, interval-valued fuzzy set, intuitionistic fuzzy set. Elements of Neutrosophic set are characterized by a truth-membership function, falsity and also indeterminacy which is a more realistic way of expressing the parameters in real life problem. Here the elements of the cost matrix for the GAP are considered as neutrosophic elements which have not been considered earlier by any other author. The problem has been solved by evaluating score function matrix and then solving it by Extremum Difference Method (EDM [1] to get the optimal assignment. The method has been demonstrated by a suitable numerical example.

Using interviews to understand the assignment mechanism in a nonexperimental study: the case of eighth grade algebra.

Science.gov (United States)

Rickles, Jordan H

2011-10-01

Many inquiries regarding the causal effects of policies or programs are based on research designs where the treatment assignment process is unknown, and thus valid inferences depend on tenuous assumptions about the assignment mechanism. This article draws attention to the importance of understanding the assignment mechanism in policy and program evaluation studies, and illustrates how information collected through interviews can develop a richer understanding of the assignment mechanism. Focusing on the issue of student assignment to algebra in 8th grade, I show how a preliminary data collection effort aimed at understanding the assignment mechanism is particularly beneficial in multisite observational studies in education. The findings, based on ten interviews and administrative data from a large school district, draw attention to the often ignored heterogeneity in the assignment mechanism across schools. These findings likely extend beyond the current research project in question to related educational policy issues such as ability grouping, tracking, differential course taking, and curricular intensity, as well as other social programs in which the assignment mechanism can differ across sites.

Automated Negotiation for Resource Assignment in Wireless Surveillance Sensor Networks

Directory of Open Access Journals (Sweden)

Enrique de la Hoz

2015-11-01

Full Text Available Due to the low cost of CMOS IP-based cameras, wireless surveillance sensor networks have emerged as a new application of sensor networks able to monitor public or private areas or even country borders. Since these networks are bandwidth intensive and the radioelectric spectrum is limited, especially in unlicensed bands, it is mandatory to assign frequency channels in a smart manner. In this work, we propose the application of automated negotiation techniques for frequency assignment. Results show that these techniques are very suitable for the problem, being able to obtain the best solutions among the techniques with which we have compared them.

Evoked Feelings, Assigned Meanings and Constructed Knowledge Based on Mistakes

Directory of Open Access Journals (Sweden)

Luciane Guimarães Batistella Bianchini

2017-09-01

Full Text Available By means of Piaget's critical clinical method, the study investigated the meanings assigned to mistakes by four students in different activities and interactive situations. The research also analyzed the results of using self-regulatory situations in understanding mistakes initially committed by the students. Data collection instruments consisted of games, video recordings, diaries and interviews. Following intervention, the students were able to recognize their competence, establish positive interactions within the group, and avoid viewing mistakes as obstacles to learning. We concluded that the meanings assigned to mistakes depend on certain variables, among them feelings nurtured by the individuals about themselves, the other, and the object of knowledge.

29 CFR 785.37 - Home to work on special one-day assignment in another city.

Science.gov (United States)

2010-07-01

... 29 Labor 3 2010-07-01 2010-07-01 false Home to work on special one-day assignment in another city... WORKED Application of Principles Traveltime § 785.37 Home to work on special one-day assignment in..., DC, with regular working hours from 9 a.m. to 5 p.m. may be given a special assignment in New York...

On the extreme points of the core of neighbour games and assignment games

NARCIS (Netherlands)

Hamers, H.J.M.; Klijn, F.; Solymosi, T.; Tijs, S.H.; Pere Villar, J.

1999-01-01

Neighbour games arise from certain matching or sequencing situations in which only some specific pairs of players can obtain a positive gain. As a consequence, neighbour games are as well assignment games as line graph restricted games. We will show that the intersection of the class of assignment

Strategies to Support PGCE Mathematics and Science Students Preparing for Assignments at Masters Level

OpenAIRE

Tas, Maarten; Forsythe, Sue

2010-01-01

The main aim of this study was to analyse and evaluate the effectiveness of support strategies being put into place for students who need to write assignments at Masters Level. In preparation for writing a 5000 word assignment on an aspect of teaching Mathematics or Science, 57 Science and Mathematics PGCE students were asked to write a 500 word synopsis which included an introduction, description of the main focus, questions that the assignment would address and possible strategies for teach...

Calibration of a joint time assignment and mode choice model system

OpenAIRE

Greeven, Paulina; Jara-Diaz, Sergio R.; Munizaga, Marcela A.; Axhausen, Kay W.

2005-01-01

In this paper we report the results of applying a new microeconomic framework to model time assignment to activities, goods consumption and mode choice jointly (Jara-Díaz and Guevara, 2003; Jara-Díaz and Guerra, 2003) that identifies the links between these decisions and permits the calculation of all the components of the subjective value of time defined in the literature: the value of time as a resource, value of assigning time to a specific activity and the value of saving time in a specif...

Assignment about providing of substitute haptic interface for visually disabled persons

OpenAIRE

浅川, 貴史

2013-01-01

[Abstract] This paper is described about an assignment of haptic interface. We have made a proposal for a music baton system for visually disabled persons. The system is constituted by an acceleration sensor, a radio module, and a haptic interface device. We have carried out an experiment of comparing the visual and the haptic interface. The assignments are declared by the results that are rise-time of a motor and pre-motion. In the paper, we make a proposal for new method of the voltage cont...

Study on store-space assignment based on logistic AGV in e-commerce goods to person picking pattern

Science.gov (United States)

Xu, Lijuan; Zhu, Jie

2017-10-01

This paper studied on the store-space assignment based on logistic AGV in E-commerce goods to person picking pattern, and established the store-space assignment model based on the lowest picking cost, and design for store-space assignment algorithm after the cluster analysis based on similarity coefficient. And then through the example analysis, compared the picking cost between store-space assignment algorithm this paper design and according to item number and storage according to ABC classification allocation, and verified the effectiveness of the design of the store-space assignment algorithm.

Threat evaluation and weapon assignment decision support: A ...

African Journals Online (AJOL)

... stands within the context of a ground based air defence system (GBADS) at the turn of the twenty first century. However, much of the contents of the paper maye generalized to military environments other than a GBADS one. Keywords: Threat evaluation, weapon assignment, decision support. ORiON Vol. 23 (2) 2007: pp.

Optimal resource assignment in workflows for maximizing cooperation

NARCIS (Netherlands)

Kumar, Akhil; Dijkman, R.M.; Song, Minseok; Daniel, Fl.; Wang, J.; Weber, B.

2013-01-01

A workflow is a team process since many actors work on various tasks to complete an instance. Resource management in such workflows deals with assignment of tasks to workers or actors. In team formation, it is necessary to ensure that members of a team are compatible with each other. When a workflow

Optimal Weight Assignment for a Chinese Signature File.

Science.gov (United States)

Liang, Tyne; And Others

1996-01-01

Investigates the performance of a character-based Chinese text retrieval scheme in which monogram keys and bigram keys are encoded into document signatures. Tests and verifies the theoretical predictions of the optimal weight assignments and the minimal false hit rate in experiments using a real Chinese corpus for disyllabic queries of different…

Likelihood of being seen within emergency departments’ assigned urgency times for poisoned and injured individuals

Directory of Open Access Journals (Sweden)

Rachel L. Rosenthal

2014-10-01

Full Text Available The objective of the present study is to determine the likelihood of injured or poisoned patients in special populations, such as those patients that are elderly and self-injurious, being seen within an emergency department’s triage nurse assigned urgency. Data from the National Hospital Ambulatory Medical Care Survey (2007 was utilized in this study. Multi-level models and multivariate linear regression models were used; patient age, sex, reported pain levels, wait time, and injury type were examined as potential predictors of being seen within assigned urgency. From a random sample across all US Emergency Departments, 5616 patients nested in 312 hospital emergency departments were included into the study. Typically, approximately 1 in 5 emergency department patients were not seen within their triage nurse assigned urgencies. The typical patient in the average hospital had an 81% likelihood of being seen within their assigned urgency. P atients who were oldest [odds ratio (OR=0.0990] and had self-inflicted injuries (vs assault OR=1.246 and OR=1.596 had the least likelihood to be seen within their assigned urgencies. As actual wait-time increased for patients, they were less likely to be seen within their assigned urgencies. The most powerful predictors of the study’s outcome were injury type and age, indicating that patients from special populations such as the elderly or those with injuries resulting from deliberate self-harm are less likely to be actually priority patients independent of triage nurse assigned urgencies.

Sensor assignment to mission in AI-TECD

Science.gov (United States)

Ganger, Robert; de Mel, Geeth; Pham, Tien; Rudnicki, Ronald; Schreiber, Yonatan

2016-05-01

Sensor-mission assignment involves the allocation of sensors and other information-providing resources to missions in order to cover the information needs of the individual tasks within each mission. The importance of efficient and effective means to find appropriate resources for tasks is exacerbated in the coalition context where the operational environment is dynamic and a multitude of critically important tasks need to achieve their collective goals to meet the objectives of the coalition. The Sensor Assignment to Mission (SAM) framework—a research product of the International Technology Alliance in Network and Information Sciences (NIS-ITA) program—provided the first knowledge intensive resource selection approach for the sensor network domain so that contextual information could be used to effectively select resources for tasks in coalition environments. Recently, CUBRC, Inc. was tasked with operationalizing the SAM framework through the use of the I2WD Common Core Ontologies for the Communications-Electronics Research, Development and Engineering Center (CERDEC) sponsored Actionable Intelligence Technology Enabled Capabilities Demonstration (AI-TECD). The demonstration event took place at Fort Dix, New Jersey during July 2015, and this paper discusses the integration and the successful demonstration of the SAM framework within the AI-TECD, lessons learned, and its potential impact in future operations.

The phase-resolved photoacoustic method to indicate chemical assignments of paracetamol

Science.gov (United States)

Camilotti, J. G.; Somer, A.; Costa, G. F.; Ribeiro, M. A.; Bonardi, C.; Cruz, G. K.; Gómez, S. L.; Beltrame, F. L.; Medina, A. N.; Sato, F.; Astrath, N. G. C.; Novatski, A.

2014-03-01

In this work, the phase-resolved photoacoustic method was applied to provide specific information on the chemical assignments of paracetamol in the near-infrared region. Two broad bands, centered at 1370 and 1130 nm, were well-resolved using this method, making it possible to assign the peaks centered at 1398, 1355 and 1295 nm to a C-H combination from a CH3 structure and the peak at 1305 nm to a C-H combination from the aromatic ring. This information represents a new finding in chemical studies regarding this medicament.

Comparing two K-category assignments by a K-category correlation coefficient

DEFF Research Database (Denmark)

Gorodkin, Jan

2004-01-01

Predicted assignments of biological sequences are often evaluated by Matthews correlation coefficient. However, Matthews correlation coefficient applies only to cases where the assignments belong to two categories, and cases with more than two categories are often artificially forced into two...... categories by considering what belongs and what does not belong to one of the categories, leading to the loss of information. Here, an extended correlation coefficient that applies to K-categories is proposed, and this measure is shown to be highly applicable for evaluating prediction of RNA secondary...

Assessment of Random Assignment in Training and Test Sets using Generalized Cluster Analysis Technique

Directory of Open Access Journals (Sweden)

Sorana D. BOLBOACĂ

2011-06-01

Full Text Available Aim: The properness of random assignment of compounds in training and validation sets was assessed using the generalized cluster technique. Material and Method: A quantitative Structure-Activity Relationship model using Molecular Descriptors Family on Vertices was evaluated in terms of assignment of carboquinone derivatives in training and test sets during the leave-many-out analysis. Assignment of compounds was investigated using five variables: observed anticancer activity and four structure descriptors. Generalized cluster analysis with K-means algorithm was applied in order to investigate if the assignment of compounds was or not proper. The Euclidian distance and maximization of the initial distance using a cross-validation with a v-fold of 10 was applied. Results: All five variables included in analysis proved to have statistically significant contribution in identification of clusters. Three clusters were identified, each of them containing both carboquinone derivatives belonging to training as well as to test sets. The observed activity of carboquinone derivatives proved to be normal distributed on every. The presence of training and test sets in all clusters identified using generalized cluster analysis with K-means algorithm and the distribution of observed activity within clusters sustain a proper assignment of compounds in training and test set. Conclusion: Generalized cluster analysis using the K-means algorithm proved to be a valid method in assessment of random assignment of carboquinone derivatives in training and test sets.

Synthetical analysis of the spin assignment for the superdeformed bands in A≅190 region

International Nuclear Information System (INIS)

Di Yaomin

2002-01-01

The spin assignment for the superdeformed bands of even-even nuclei in A ≅190 region is given by means of using the method of synthetical analysis. The I( I + 1) expression is used to fit the experimental data of the transition γ energies. In contrast to other procedure, the convergence process of the series expansions is put stress upon, whereas taking how many terms exactly in the expression does not emphasized. Moreover as well as the method of fitting the physical quantity, by use of these series expansions the moment of inertia of band heads is also calculated and then the systematics is used for the spin assignments. In practice, when the experimental data is abundant the systematics of the moment of inertia of band heads is more efficient than the method of fitting the physical quantity in the spin assignment. As for a few bands which spin assignment is difficult, the deviation from the typical rotational bands must be considered, which may be judged easily from the second class of moment of inertia of the bands. Finally the results of the spin assignment and the comparison with other literature are presented. These results should be more reliable

Ner protein of phage Mu: Assignments using {sup 13}C/{sup 15}N-labeled protein

Energy Technology Data Exchange (ETDEWEB)

Strzelecka, T.; Gronenborn, A.M.; Clore, G.M. [National Institutes of Health, Bethesda, MD (United States)

1994-12-01

The Ner protein is a small (74-amino acid) DNA-binding protein that regulates a switch between the lysogenic and lytic stages of phage Mu. It inhibits expression of the C repressor gene and down-regulates its own expression. Two-dimensional NMR experiments on uniformly {sup 15}N-labeled protein provided most of the backbone and some of the sidechain proton assignments. The secondary structure determination using two-dimensional NOESY experiments showed that Ner consists of five {alpha}-helices. However, because most of the sidechain protons could not be assigned, the full structure was not determined. Using uniformly {sup 13}C/{sup 15}N-labeled Ner and a set of three-dimensional experiments, we were able to assign all of the backbone and 98% of the sidechain protons. In particular, the CBCANH and CBCA(CO)NH experiments were used to sequentially assign the C{alpha} and C{beta} resonances; the HCCH-CTOCSY and HCCH-COSY were used to assign sidechain carbon and proton resonances.

Probabilistic Identification of Spin Systems and their Assignments including Coil-Helix Inference as Output (PISTACHIO)

Energy Technology Data Exchange (ETDEWEB)

Eghbalnia, Hamid R., E-mail: eghbalni@nmrfam.wisc.edu; Bahrami, Arash; Wang, Liya [National Magnetic Resonance Facility at Madison, Biochemistry Department (United States); Assadi, Amir [University of Wisconsin-Madison, Mathematics Department (United States); Markley, John L [National Magnetic Resonance Facility at Madison, Biochemistry Department (United States)

2005-07-15

We present a novel automated strategy (PISTACHIO) for the probabilistic assignment of backbone and sidechain chemical shifts in proteins. The algorithm uses peak lists derived from various NMR experiments as input and provides as output ranked lists of assignments for all signals recognized in the input data as constituting spin systems. PISTACHIO was evaluated by comparing its performance with raw peak-picked data from 15 proteins ranging from 54 to 300 residues; the results were compared with those achieved by experts analyzing the same datasets by hand. As scored against the best available independent assignments for these proteins, the first-ranked PISTACHIO assignments were 80-100% correct for backbone signals and 75-95% correct for sidechain signals. The independent assignments benefited, in a number of cases, from structural data (e.g. from NOESY spectra) that were unavailable to PISTACHIO. Any number of datasets in any combination can serve as input. Thus PISTACHIO can be used as datasets are collected to ascertain the current extent of secure assignments, to identify residues with low assignment probability, and to suggest the types of additional data needed to remove ambiguities. The current implementation of PISTACHIO, which is available from a server on the Internet, supports input data from 15 standard double- and triple-resonance experiments. The software can readily accommodate additional types of experiments, including data from selectively labeled samples. The assignment probabilities can be carried forward and refined in subsequent steps leading to a structure. The performance of PISTACHIO showed no direct dependence on protein size, but correlated instead with data quality (completeness and signal-to-noise). PISTACHIO represents one component of a comprehensive probabilistic approach we are developing for the collection and analysis of protein NMR data.

Probabilistic Identification of Spin Systems and their Assignments including Coil-Helix Inference as Output (PISTACHIO)

International Nuclear Information System (INIS)

Eghbalnia, Hamid R.; Bahrami, Arash; Wang, Liya; Assadi, Amir; Markley, John L.

2005-01-01

We present a novel automated strategy (PISTACHIO) for the probabilistic assignment of backbone and sidechain chemical shifts in proteins. The algorithm uses peak lists derived from various NMR experiments as input and provides as output ranked lists of assignments for all signals recognized in the input data as constituting spin systems. PISTACHIO was evaluated by comparing its performance with raw peak-picked data from 15 proteins ranging from 54 to 300 residues; the results were compared with those achieved by experts analyzing the same datasets by hand. As scored against the best available independent assignments for these proteins, the first-ranked PISTACHIO assignments were 80-100% correct for backbone signals and 75-95% correct for sidechain signals. The independent assignments benefited, in a number of cases, from structural data (e.g. from NOESY spectra) that were unavailable to PISTACHIO. Any number of datasets in any combination can serve as input. Thus PISTACHIO can be used as datasets are collected to ascertain the current extent of secure assignments, to identify residues with low assignment probability, and to suggest the types of additional data needed to remove ambiguities. The current implementation of PISTACHIO, which is available from a server on the Internet, supports input data from 15 standard double- and triple-resonance experiments. The software can readily accommodate additional types of experiments, including data from selectively labeled samples. The assignment probabilities can be carried forward and refined in subsequent steps leading to a structure. The performance of PISTACHIO showed no direct dependence on protein size, but correlated instead with data quality (completeness and signal-to-noise). PISTACHIO represents one component of a comprehensive probabilistic approach we are developing for the collection and analysis of protein NMR data

A singular value sensitivity approach to robust eigenstructure assignment

DEFF Research Database (Denmark)

Søgaard-Andersen, Per; Trostmann, Erik; Conrad, Finn

1986-01-01

A design technique for improving the feedback properties of multivariable state feedback systems designed using eigenstructure assignment is presented. Based on a singular value analysis of the feedback properties a design parameter adjustment procedure is outlined. This procedure allows...

Developing Team Skills through a Collaborative Writing Assignment

Science.gov (United States)

Thomas, Theda Ann

2014-01-01

Employers want students who are able to work effectively as members of a team, and expect universities to develop this ability in their graduates. This paper proposes a framework for a collaborative writing assignment that specifically develops students' ability to work in teams. The framework has been tested using two iterations of an action…

Careerism, Committee Assignments and the Electoral Connection

OpenAIRE

Katz, Jonathan N.; Sala, Brian R.

1996-01-01

Most scholars agree that members of Congress are strongly motivated by their desire for reelection. This assumption implies that members of Congress adopt institutions, rules, and norms of behavior in part to serve their electoral interests. Direct tests of the electoral connection are rare, however, because significant, exogenous changes in the electoral environment are difficult to identify. We develop and test an electoral rationale for the norm of committee assignment "property rights...

A fuzzy-based particle swarm optimisation approach for task assignment in home healthcare

Directory of Open Access Journals (Sweden)

Mutingi, Michael

2014-11-01

Full Text Available Home healthcare (HHC organisations provide coordinated healthcare services to patients at their homes. Motivated by the ever-increasing need for home-based care, the assignment of tasks to available healthcare staff is a common and complex problem in homecare organisations. Designing high quality task schedules is critical for improving worker morale, job satisfaction, service efficiency, service quality, and competitiveness over the long term. The desire is to provide high quality task assignment schedules that satisfy the patient, the care worker, and the management. This translates to maximising schedule fairness in terms of workload assignments, avoiding task time window violation, and meeting management goals as much as possible. However, in practice, these desires are often subjective as they involve imprecise human perceptions. This paper develops a fuzzy multi-criteria particle swarm optimisation (FPSO approach for task assignment in a home healthcare setting in a fuzzy environment. The proposed approach uses a fuzzy evaluation method from a multi-criteria point of view. Results from illustrative computational experiments show that the approach is promising.

Dynamic activity-travel assignment in multi-state supernetworks with road and location capacity constraints

NARCIS (Netherlands)

Liu, P.; Liao, F.; Huang, H.; Timmermans, H.J.P.

2016-01-01

A unified framework coupling activity-based modelling and dynamic traffic assignment has recently been proposed. It formulates dynamic activity-travel assignment (DATA) in multi-state supernetworks as a dynamic user equilibrium. Choices of departure time, route, mode, activity sequence, and

A Simple Method for Solving Fully Intuitionistic Fuzzy Real Life Assignment Problem

OpenAIRE

Senthil Kumar, P.; Jahir Hussain, R.

2016-01-01

In solving real life assignment problem we often face the state of uncertainty as well as hesitation due to various uncontrollable factors. To deal with uncertainty and hesitation many authors have suggested the intuitionistic fuzzy representations for the data. So, in this paper, the authors consider the assignment problem having uncertainty and hesitation in cost/time/profit. They formulate the problem and utilize triangular intuitionistic fuzzy numbers (TIFNs) to deal with uncertainty and ...

The Kinetics of Chirality Assignment in Catalytic Single Walled Carbon Nanotube Growth

OpenAIRE

Xu, Ziwei; Yan, Tianying; Ding, Feng

2014-01-01

Chirality-selected single-walled carbon nanotubes (SWCNTs) ensure a great potential of building ~1 nm sized electronics. However, the reliable method for chirality-selected SWCNT is still pending. Here we present a theoretical study on the SWCNT's chirality assignment and control during the catalytic growth. This study reveals that the chirality of a SWCNT is determined by the kinetic incorporation of the pentagon formation during SWCNT nucleation. Therefore, chirality is randomly assigned on...

Protect Heterogeneous Environment Distributed Computing from Malicious Code Assignment

Directory of Open Access Journals (Sweden)

V. S. Gorbatov

2011-09-01

Full Text Available The paper describes the practical implementation of the protection system of heterogeneous environment distributed computing from malicious code for the assignment. A choice of technologies, development of data structures, performance evaluation of the implemented system security are conducted.

NEW CRITERIA FOR ASSIGNING WASTE CONTAINING TECH-NOGENIC RADIONUCLIDES TO THE RADIOACTIVE WASTE

Directory of Open Access Journals (Sweden)

I. K. Romanovich

2010-01-01

Full Text Available The article contains detailed description of criteria for assigning of liquid and gaseous industrial waste containing technogenicradionuclides to the radioactive waste, presented in the new Basic Sanitary Rulesof Radiation Safety (OSPORB-99/2010. The analysisof shortcomings and discrepancies of the previously used in Russia system of criteria for assigning waste to the radioactive waste is given.

The (digital) natives are restless: designing and implementing an interactive digital media assignment.

Science.gov (United States)

Voge, Catherine; Hirvela, Kari; Jarzemsky, Paula

2012-01-01

To create an opportunity for students to connect with the Quality and Safety Education for Nurses competencies and demonstrate learning via knowledge transference, the authors piloted a digital media assignment. Students worked in small groups to create an unfolding patient care scenario with embedded decision points, using presentation software. The authors discuss the assignment and its outcomes.

APSY-NMR for protein backbone assignment in high-throughput structural biology

Energy Technology Data Exchange (ETDEWEB)

Dutta, Samit Kumar; Serrano, Pedro; Proudfoot, Andrew; Geralt, Michael [The Scripps Research Institute, Department of Integrative Structural and Computational Biology (United States); Pedrini, Bill [Paul Scherrer Institute (PSI), SwissFEL Project (Switzerland); Herrmann, Torsten [Université de Lyon, Institut des Sciences Analytiques, Centre de RMN à Très Hauts Champs, UMR 5280 CNRS, ENS Lyon, UCB Lyon 1 (France); Wüthrich, Kurt, E-mail: wuthrich@scripps.edu [The Scripps Research Institute, Department of Integrative Structural and Computational Biology (United States)

2015-01-15

A standard set of three APSY-NMR experiments has been used in daily practice to obtain polypeptide backbone NMR assignments in globular proteins with sizes up to about 150 residues, which had been identified as targets for structure determination by the Joint Center for Structural Genomics (JCSG) under the auspices of the Protein Structure Initiative (PSI). In a representative sample of 30 proteins, initial fully automated data analysis with the software UNIO-MATCH-2014 yielded complete or partial assignments for over 90 % of the residues. For most proteins the APSY data acquisition was completed in less than 30 h. The results of the automated procedure provided a basis for efficient interactive validation and extension to near-completion of the assignments by reference to the same 3D heteronuclear-resolved [{sup 1}H,{sup 1}H]-NOESY spectra that were subsequently used for the collection of conformational constraints. High-quality structures were obtained for all 30 proteins, using the J-UNIO protocol, which includes extensive automation of NMR structure determination.

More Districts Factoring Poverty into Student-Assignment Plans

Science.gov (United States)

Zehr, Mary Ann

2010-01-01

A growing number of school districts are trying to break up concentrations of poverty on their campuses by taking students' family income into consideration in school assignments. Some of the districts replaced race with socioeconomic status as a determining indicator after the U.S. Supreme Court ruled in 2007 that using race as the primary factor…

The role of high-level calculations in the assignment of the Q-band spectra of chlorophyll

Energy Technology Data Exchange (ETDEWEB)

Reimers, Jeffrey R. [School of Physics and Materials Science, The University of Technology, Sydney NSW (Australia); Cai, Zheng-Li [School of Chemistry, Physics and Mechanical Engineering, Queensland University of Technology, Brisbane QLD4001 (Australia); Kobayashi, Rika [Australian National University Supercomputer Facility, Mills Rd, Canberra, ACT 0200 (Australia); Rätsep, Margus [Institute of Physics, University of Tartu, Riia 142, 51014 Tartu (Estonia); Freiberg, Arvi [Institute of Physics, University of Tartu, Riia 142, 51014 Tartu, Estonia and Institute of Molecular and Cell Biology, University of Tartu, Riia 23, 51010 Tartu (Estonia); Krausz, Elmars [Research School of Chemistry, The Australian National University, Canberra 2601 (Australia)

2014-10-06

We recently established a novel assignment of the visible absorption spectrum of chlorophyll-a that sees the two components Q{sub x} and Q{sub y} of the low-energy Q band as being intrinsically mixed by non-adiabatic coupling. This ended 50 years debate as to the nature of the Q bands, with prior discussion poised only in the language of the Born-Oppenheimer and Condon approximations. The new assignment presents significant ramifications for exciton transport and quantum coherence effects in photosystems. Results from state of the art electronic structure calculations have always been used to justify assignments, but quantitative inaccuracies and systematic failures have historically limited usefulness. We examine the role of CAM-B3LYP time-dependent density-functional theory (TD-DFT) and Symmetry Adapted Cluster-Configuration Interaction (SAC-CI) calculations in first showing that all previous assignments were untenable, in justifying the new assignment, in making some extraordinary predictions that were vindicated by the new assignment, and in then identifying small but significant anomalies in the extensive experimental data record.

Optimal assignment methods in three-form planned missing data designs for longitudinal panel studies

NARCIS (Netherlands)

Jorgensen, T.D.; Rhemtulla, M.; Schoemann, A.; McPherson, B.; Wu, W.; Little, T.D.

2014-01-01

Planned missing designs are becoming increasingly popular, but because there is no consensus on how to implement them in longitudinal research, we simulated longitudinal data to distinguish between strategies of assigning items to forms and of assigning forms to participants across measurement

Evolution of Various Library Instruction Strategies: Using Student Feedback to Create and Enhance Online Active Learning Assignments

Directory of Open Access Journals (Sweden)

Marcie Lynne Jacklin

2013-06-01

Full Text Available This case study traces the evolution of library assignments for biological science students from paper-based workbooks in a blended (hands-on workshop to blended learning workshops using online assignments to online active learning modules which are stand-alone without any face-to-face instruction. As the assignments evolved to adapt to online learning supporting materials in the form of PDFs (portable document format, screen captures and screencasting were embedded into the questions as teaching moments to replace face-to-face instruction. Many aspects of the evolution of the assignment were based on student feedback from evaluations, input from senior lab demonstrators and teaching assistants, and statistical analysis of the students’ performance on the assignment. Advantages and disadvantages of paper-based and online assignments are discussed. An important factor for successful online learning may be the ability to get assistance.

Analyzing the multiple-target-multiple-agent scenario using optimal assignment algorithms

Science.gov (United States)

Kwok, Kwan S.; Driessen, Brian J.; Phillips, Cynthia A.; Tovey, Craig A.

1997-09-01

This work considers the problem of maximum utilization of a set of mobile robots with limited sensor-range capabilities and limited travel distances. The robots are initially in random positions. A set of robots properly guards or covers a region if every point within the region is within the effective sensor range of at least one vehicle. We wish to move the vehicles into surveillance positions so as to guard or cover a region, while minimizing the maximum distance traveled by any vehicle. This problem can be formulated as an assignment problem, in which we must optimally decide which robot to assign to which slot of a desired matrix of grid points. The cost function is the maximum distance traveled by any robot. Assignment problems can be solved very efficiently. Solution times for one hundred robots took only seconds on a silicon graphics crimson workstation. The initial positions of all the robots can be sampled by a central base station and their newly assigned positions communicated back to the robots. Alternatively, the robots can establish their own coordinate system with the origin fixed at one of the robots and orientation determined by the compass bearing of another robot relative to this robot. This paper presents example solutions to the multiple-target-multiple-agent scenario using a matching algorithm. Two separate cases with one hundred agents in each were analyzed using this method. We have found these mobile robot problems to be a very interesting application of network optimization methods, and we expect this to be a fruitful area for future research.

Analyzing the multiple-target-multiple-agent scenario using optimal assignment algorithms

International Nuclear Information System (INIS)

Kwok, K.S.; Driessen, B.J.; Phillips, C.A.; Tovey, C.A.

1997-01-01

This work considers the problem of maximum utilization of a set of mobile robots with limited sensor-range capabilities and limited travel distances. The robots are initially in random positions. A set of robots properly guards or covers a region if every point within the region is within the effective sensor range of at least one vehicle. The authors wish to move the vehicles into surveillance positions so as to guard or cover a region, while minimizing the maximum distance traveled by any vehicle. This problem can be formulated as an assignment problem, in which they must optimally decide which robot to assign to which slot of a desired matrix of grid points. The cost function is the maximum distance traveled by any robot. Assignment problems can be solved very efficiently. Solutions times for one hundred robots took only seconds on a Silicon Graphics Crimson workstation. The initial positions of all the robots can be sampled by a central base station and their newly assigned positions communicated back to the robots. Alternatively, the robots can establish their own coordinate system with the origin fixed at one of the robots and orientation determined by the compass bearing of another robot relative to this robot. This paper presents example solutions to the multiple-target-multiple-agent scenario using a matching algorithm. Two separate cases with one hundred agents in each were analyzed using this method. They have found these mobile robot problems to be a very interesting application of network optimization methods, and they expect this to be a fruitful area for future research

A multiobjective approach towards weapon assignment in a ground ...

African Journals Online (AJOL)

A typical ground-based air defence (GBAD) environment comprises defended assets on the ground which require protection from enemy aircraft entering the defended airspace. ... of computerised threat evaluation and weapon assignment (TEWA) decision support systems (DSSs) within the context of a GBAD system.

Artificial intelligence applied to assigned merchandise location in retail sales systems

Directory of Open Access Journals (Sweden)

Cruz-Domínguez, O.

2016-05-01

Full Text Available This paper presents an option for improving the process of assigning storage locations for merchandise in a warehouse. A disadvantage of policies in the literature is that the merchandise is assigned allocation only according to the volume of sales and the rotation it presents. However, in some cases it is necessary to deal with other aspects such as family group membership, the physical characteristics of the products, and their sales pattern to design an integral policy. This paper presents an alternative to the afore- mentioned process using Flexsim®, artificial neural networks, and genetic algorithms.

Integrated assignment and path planning

Science.gov (United States)

Murphey, Robert A.

2005-11-01

A surge of interest in unmanned systems has exposed many new and challenging research problems across many fields of engineering and mathematics. These systems have the potential of transforming our society by replacing dangerous and dirty jobs with networks of moving machines. This vision is fundamentally separate from the modern view of robotics in that sophisticated behavior is realizable not by increasing individual vehicle complexity, but instead through collaborative teaming that relies on collective perception, abstraction, decision making, and manipulation. Obvious examples where collective robotics will make an impact include planetary exploration, space structure assembly, remote and undersea mining, hazardous material handling and clean-up, and search and rescue. Nonetheless, the phenomenon driving this technology trend is the increasing reliance of the US military on unmanned vehicles, specifically, aircraft. Only a few years ago, following years of resistance to the use of unmanned systems, the military and civilian leadership in the United States reversed itself and have recently demonstrated surprisingly broad acceptance of increasingly pervasive use of unmanned platforms in defense surveillance, and even attack. However, as rapidly as unmanned systems have gained acceptance, the defense research community has discovered the technical pitfalls that lie ahead, especially for operating collective groups of unmanned platforms. A great deal of talent and energy has been devoted to solving these technical problems, which tend to fall into two categories: resource allocation of vehicles to objectives, and path planning of vehicle trajectories. An extensive amount of research has been conducted in each direction, yet, surprisingly, very little work has considered the integrated problem of assignment and path planning. This dissertation presents a framework for studying integrated assignment and path planning and then moves on to suggest an exact

The Perception Gap: Recognizing and managing the risks that arise when we get risk wrong.

Science.gov (United States)

Ropeik, David

2012-05-01

Many in the academic, science, and business communities are frustrated at how people perceive and respond to risk, lamenting that the lay public is sometimes more afraid of some threats than the evidence warrants, and less afraid of some dangers than the evidence warns. This is often ascribed to the alarmist way the news media cover risk-related subjects. That criticism is simplistic and unproductive, and ignores or dismisses the large body of research that finds that the perception of risk is not, and can never be, perfectly rational. Risk perception among members of the public, the media, and members of the academic, scientific, and business communities, is ultimately subjective. The gap between our fears and the evidence is not simply the product of alarmist media reporting. This 'Perception Gap' poses significant risks in and of itself, influencing the choices we make as individuals and as a society. The roots of the Perception Gap must be understood if we are to recognize the dangers that can arise when we sometimes get risk wrong, and in order that we may more wisely manage those risks as actively as we manage toxicological or food or other risks with which we are more familiar. Copyright © 2012 Elsevier Ltd. All rights reserved.

Consistent assignment of nursing staff to residents in nursing homes: a critical review of conceptual and methodological issues.

Science.gov (United States)

Roberts, Tonya; Nolet, Kimberly; Bowers, Barbara

2015-06-01

Consistent assignment of nursing staff to residents is promoted by a number of national organizations as a strategy for improving nursing home quality and is included in pay for performance schedules in several states. However, research has shown inconsistent effects of consistent assignment on quality outcomes. In order to advance the state of the science of research on consistent assignment and inform current practice and policy, a literature review was conducted to critique conceptual and methodological understandings of consistent assignment. Twenty original research reports of consistent assignment in nursing homes were found through a variety of search strategies. Consistent assignment was conceptualized and operationalized in multiple ways with little overlap from study to study. There was a lack of established methods to measure consistent assignment. Methodological limitations included a lack of control and statistical analyses of group differences in experimental-level studies, small sample sizes, lack of attention to confounds in multicomponent interventions, and outcomes that were not theoretically linked. Future research should focus on developing a conceptual understanding of consistent assignment focused on definition, measurement, and links to outcomes. To inform current policies, testing consistent assignment should include attention to contexts within and levels at which it is most effective. Published by Oxford University Press on behalf of the Gerontological Society of America 2013.

Complete sequence-specific 1H NMR assignments for human insulin

International Nuclear Information System (INIS)

Kline, A.D.; Justice, R.M. Jr.

1990-01-01

Solvent conditions where human insulin could be studied by high-resolution NMR were determined. Both low pH and addition of acetonitrile were required to overcome the protein's self-association and to obtain useful spectra. Two hundred eighty-six 1 H resonances were located and assigned to specific sites on the protein by using two-dimensional NMR methods. The presence and position of numerous d NN sequential NOE's indicate that the insulin conformation seen in crystallographic studies is largely retained under these solution conditions. Slowly exchanging protons were observed for seven backbone amide protons and were assigned to positions A15 and A16 and to positions B15-B19. These amides all occur within helical regions of the protein

75 FR 66267 - Delegation of Authority and Assignment of Responsibility; Secretary's Order 6-2010

Science.gov (United States)

2010-10-27

... Business Act, as amended, 15 U.S.C. 644(n). (14) Social Security Act of 1935, as amended, Title III-Grants... Part V Department of Labor Delegation of Authority and Assignment of Responsibility; Secretary's... of Responsibility; Secretary's Order 6-2010 Subject: Delegation of Authority and Assignment of...

Revisit assignments of the new excited Ω{sub c} states with QCD sum rules

Energy Technology Data Exchange (ETDEWEB)

Wang, Zhi-Gang; Wei, Xing-Ning; Yan, Ze-Hui [North China Electric Power University, Department of Physics, Baoding (China)

2017-12-15

In this article, we distinguish the contributions of the positive parity and negative parity Ω{sub c} states, study the masses and pole residues of the 1S, 1P, 2S and 2P Ω{sub c} states with the spin J = (1)/(2) and (3)/(2) using the QCD sum rules in a consistent way, and we revisit the assignments of the new narrow excited Ω{sub c}{sup 0} states. The predictions support assigning Ω{sub c}(3000) to the 1P Ω{sub c} state with J{sup P} = (1)/(2){sup -}, assigning Ω{sub c}(3090) to the 1P Ω{sub c} state with J{sup P} = (3)/(2){sup -} or the 2S Ω{sub c} state with J{sup P} = (1)/(2){sup +}, and assigning Ω{sub c}(3119) to the 2S Ω{sub c} state with J{sup P} = (3)/(2){sup +}. (orig.)

RESCUE: An artificial neural network tool for the NMR spectral assignment of proteins

International Nuclear Information System (INIS)

Pons, J.L.; Delsuc, M.A.

1999-01-01

The assignment of the 1 H spectrum of a protein or a polypeptide is the prerequisite for advanced NMR studies. We present here an assignment tool based on the artificial neural network technology, which determines the type of the amino acid from the chemical shift values observed in the 1 H spectrum. Two artificial neural networks have been trained and extensively tested against a non-redundant subset of the BMRB chemical shift data bank [Seavey, B.R. et al. (1991) J. Biomol. NMR, 1, 217-236]. The most promising of the two accomplishes the analysis in two steps, grouping related amino acids together. It presents a mean rate of success above 80% on the test set. The second network tested separates down to the single amino acid; it presents a mean rate of success of 63%. This tool has been used to assist the manual assignment of peptides and proteins and can also be used as a block in an automated approach to assignment. The program has been called RESCUE and is made publicly available at the following URL: http://www.infobiosud.univ-montp1.fr/rescue

Due date assignment procedures with dynamically updated coefficients for multi-level assembly job shops

NARCIS (Netherlands)

Adam, N.R.; Bertrand, J.W.M.; Morehead, D.C.; Surkis, J.

1993-01-01

This paper presents a study of due date assignment procedures in job shop environments where multi-level assembly jobs are processed and due dates are internally assigned. Most of the reported studies in the literature have focused on string type jobs. We propose a dynamic update approach (which

Total synthesis and stereochemical assignment of the salicylate antitumor macrolide lobatamide C(1).

Science.gov (United States)

Shen, Ruichao; Lin, Cheng Ting; Porco, John A

2002-05-22

The total synthesis and stereochemical assignment of the potent antitumor macrolide lobatamide C is reported. The synthesis involves Cu(I)-mediated enamide formation and Na(2)CO(3)-mediated esterification of a beta-hydroxy acid and a salicylate cyanomethyl ester. Macrolactonization was accomplished using a Mitsunobu protocol. The stereochemical assignment of lobatamide C was achieved by Mosher ester analysis and comparison with prepared stereoisomers.

Mapping Learning Outcomes and Assignment Tasks for SPIDER Activities

Directory of Open Access Journals (Sweden)

Lyn Brodie

2011-05-01

Full Text Available Modern engineering programs have to address rapidly changing technical content and have to enable students to develop transferable skills such as critical evaluation, communication skills and lifelong learning. This paper introduces a combined learning and assessment activity that provides students with opportunities to develop and practice their soft skills, but also extends their theoretical knowledge base. Key tasks included self directed inquiry, oral and written communication as well as peer assessment. To facilitate the SPIDER activities (Select, Prepare and Investigate, Discuss, Evaluate, Reflect, a software tool has been implemented in the learning management system Moodle. Evidence shows increased student engagement and better learning outcomes for both transferable as well as technical skills. The study focuses on generalising the relationship between learning outcomes and assignment tasks as well as activities that drive these tasks. Trail results inform the approach. Staff evaluations and their views of assignments and intended learning outcomes also supported this analysis.

Midwifery students' evaluation of team-based academic assignments involving peer-marking.

Science.gov (United States)

Parratt, Jenny A; Fahy, Kathleen M; Hastie, Carolyn R

2014-03-01

Midwives should be skilled team workers in maternity units and in group practices. Poor teamwork skills are a significant cause of adverse maternity care outcomes. Despite Australian and International regulatory requirements that all midwifery graduates are competent in teamwork, the systematic teaching and assessment of teamwork skills is lacking in higher education. How do midwifery students evaluate participation in team-based academic assignments, which include giving and receiving peer feedback? First and third year Bachelor of Midwifery students who volunteered (24 of 56 students). Participatory Action Research with data collection via anonymous online surveys. There was general agreement that team based assignments; (i) should have peer-marking, (ii) help clarify what is meant by teamwork, (iii) develop communication skills, (iv) promote student-to-student learning. Third year students strongly agreed that teams: (i) are valuable preparation for teamwork in practice, (ii) help meet Australian midwifery competency 8, and (iii) were enjoyable. The majority of third year students agreed with statements that their teams were effectively coordinated and team members shared responsibility for work equally; first year students strongly disagreed with these statements. Students' qualitative comments substantiated and expanded on these findings. The majority of students valued teacher feedback on well-developed drafts of the team's assignment prior to marking. Based on these findings we changed practice and created more clearly structured team-based assignments with specific marking criteria. We are developing supporting lessons to teach specific teamwork skills: together these resources are called "TeamUP". TeamUP should be implemented in all pre-registration Midwifery courses to foster students' teamwork skills and readiness for practice. Copyright © 2013 Australian College of Midwives. Published by Elsevier Ltd. All rights reserved.

A novel strategy for NMR resonance assignment and protein structure determination

International Nuclear Information System (INIS)

Lemak, Alexander; Gutmanas, Aleksandras; Chitayat, Seth; Karra, Murthy; Farès, Christophe; Sunnerhagen, Maria; Arrowsmith, Cheryl H.

2011-01-01

The quality of protein structures determined by nuclear magnetic resonance (NMR) spectroscopy is contingent on the number and quality of experimentally-derived resonance assignments, distance and angular restraints. Two key features of protein NMR data have posed challenges for the routine and automated structure determination of small to medium sized proteins; (1) spectral resolution – especially of crowded nuclear Overhauser effect spectroscopy (NOESY) spectra, and (2) the reliance on a continuous network of weak scalar couplings as part of most common assignment protocols. In order to facilitate NMR structure determination, we developed a semi-automated strategy that utilizes non-uniform sampling (NUS) and multidimensional decomposition (MDD) for optimal data collection and processing of selected, high resolution multidimensional NMR experiments, combined it with an ABACUS protocol for sequential and side chain resonance assignments, and streamlined this procedure to execute structure and refinement calculations in CYANA and CNS, respectively. Two graphical user interfaces (GUIs) were developed to facilitate efficient analysis and compilation of the data and to guide automated structure determination. This integrated method was implemented and refined on over 30 high quality structures of proteins ranging from 5.5 to 16.5 kDa in size.

THE ANALYSIS OF INTERFERENCE ON WRITING ASSIGNMENTS OF THE MIDWIFERY STUDENTS

Directory of Open Access Journals (Sweden)

I G. A. Agung Sintha Satwika

2013-11-01

Full Text Available This research aims at investigating and analyzing the interference which occurred in English text made by the students of Akademi Kebidanan Bali Wisnu Dharma. The data of this writing were collected from the writing assignment of the students at Akademi Kebidanan Bali Wisnu Dharma, which was divided into six groups. The data were obtained by reading intensively those texts and followed by applying the note taking technique. The result of this study indicates that the interference occurred on those writing assignments in terms of semantics level, spelling, copula, syntax, literal translation, redundancy, over generalization, and interference in terms of English pronoun.