WorldWideScience

Sample records for wire coil inserts

  1. A HTS dipole insert coil constructed

    CERN Document Server

    Ballarino, A; Rey, J M; Stenvall, A; Sorbi, M; Tixador, P

    2013-01-01

    This report is the deliverable report 7.4.1 “A HTS dipole insert coil constructed“. The report has three parts: “Design report for the HTS dipole insert”, “One insert pancake prototype coil constructed with the setup for a high field test”, and “All insert components ordered”. The three report parts show that, although the insert construction will be only completed by end 2013, all elements are present for a successful completion and that, given the important investments done by the participants, there is a full commitment of all of them to finish the project

  2. Caída de presión de un flujo turbulento en un espacio anular con hélices insertadas//The pressure drop of turbulent flow in an annular space with wire coil inserts

    Directory of Open Access Journals (Sweden)

    Josué Imbert González

    2015-05-01

    Full Text Available El trabajo presentado evaluó el comportamiento experimental de la caída de presión en un espacio anular con alambres enrollados insertados para números de Reynolds entre 1500 y 5000. La zona de prueba se seleccionó alejada de la influencia de los efectos de entrada. Anteriormente se realizaron pruebas de visualización del flujo para verificar la presencia de un flujo turbulento en esta gama del número de Reynolds. A partir de los datos experimentales se obtuvieron ecuaciones de correlación del factor de fricción para el flujo turbulento. Las ecuaciones obtenidas se compararon con los datos experimentales. Los resultados indican hasta qué punto las hélices inducen la aparición de turbulencias en un espacio anularPalabras claves: caída de presión, flujo anular, análisis hidrodinámico, visualización de flujo, hélices insertadas.______________________________________________________________________________AbstractThe work presented evaluates the experimental behavior of the pressure drop in an annular space with coiled wires inserted forReynolds numbers between 1500 and 5000. The test zone was selected away from the influence of entrance effects. Previously flow visualization tests were performed to verify the presence of a turbulent flow in this range of Reynolds number. From the experimental data were obtained correlation equations of the friction factor for turbulent flow. The equations obtained were compared with experimental data. The results indicate to what extent the helices induce the occurrence of turbulence in an annular space.Key words: drop pressure, annular flow, hydrodynamic analysis, visualization flow, wire coil inserts.

  3. Magnetic measurement with coils and wires

    CERN Document Server

    Walckiers, L

    2010-01-01

    Accelerator magnets steer particle beams according to the field integrated along the trajectory over the magnet length. Purpose-wound coils measure these relevant parameters with high precision and complement efficiently point-like measurements performed with Hall plates or NMR probes. The rotating coil method gives a complete two-dimensional description of the magnetic field in a series of normal and skew multipoles. The more recent single stretched wire is a reference instrument to measure field integrals and to find the magnetic axis.

  4. Ablation dynamics in coiled wire-array Z-pinches

    Energy Technology Data Exchange (ETDEWEB)

    Hall, G. N.; Lebedev, S. V.; Suzuki-Vidal, F.; Swadling, G.; Chittenden, J. P.; Bland, S. N.; Harvey-Thompson, A. [Blackett Laboratory, Imperial College, London SW7 2BW (United Kingdom); Knapp, P. F.; Blesener, I. C.; McBride, R. D.; Chalenski, D. A.; Blesener, K. S.; Greenly, J. B.; Pikuz, S. A.; Shelkovenko, T. A.; Hammer, D. A.; Kusse, B. R. [Laboratory of Plasma Studies, Cornell University, 439 Rhodes Hall, Ithaca, New York 14853 (United States)

    2013-02-15

    Experiments to study the ablation dynamics of coiled wire arrays were performed on the MAGPIE generator (1 MA, 240 ns) at Imperial College, and on the COBRA generator at Cornell University's Laboratory of Plasma Studies (1 MA, 100 ns). The MAGPIE generator was used to drive coiled wires in an inverse array configuration to study the distribution of ablated plasma. Using interferometry to study the plasma distribution during the ablation phase, absolute quantitative measurements of electron line density demonstrated very high density contrasts between coiled ablation streams and inter-stream regions many millimetres from the wire. The measured density contrasts for a coiled array were many times greater than that observed for a conventional array with straight wires, indicating that a much greater axial modulation of the ablated plasma may be responsible for the unique implosion dynamics of coiled arrays. Experiments on the COBRA generator were used to study the complex redirection of plasma around a coiled wire that gives rise to the ablation structure exhibited by coiled arrays. Observations of this complex 3D plasma structure were used to validate the current model of coiled array ablation dynamics [Hall et al., Phys. Rev. Lett. 100, 065003 (2008)], demonstrating irrefutably that plasma flow from the wires behaves as predicted. Coiled wires were observed to ablate and implode in the same manner on both machines, indicating that current rise time should not be an issue for the scaling of coiled arrays to larger machines with fast current rise times.

  5. Clinical Application of Insertion Force Sensor System for Coil Embolization of Intracranial Aneurysms.

    Science.gov (United States)

    Matsubara, Noriaki; Miyachi, Shigeru; Izumi, Takashi; Yamada, Hiroyuki; Marui, Naoki; Ota, Keisuke; Tajima, Hayato; Shintai, Kazunori; Ito, Masashi; Imai, Tasuku; Nishihori, Masahiro; Wakabayashi, Toshihiko

    2017-09-01

    In endovascular embolization for intracranial aneurysms, it is important to properly control the coil insertion force. However, the force can only be subjectively detected by the subtle feedback experienced by neurointerventionists at their fingertips. The authors envisioned a system that would objectively sense and quantify that force. In this article, coil insertion force was measured in cases of intracranial aneurysm using this sensor, and its actual clinical application was investigated. The sensor consists of a hemostatic valve (Y-connector). A little flexure was intentionally added in the device, and it creates a bend in the delivery wire. The sensor measures the change in the position of the bent wire depending on the insertion force and translates it into a force value. Using this, embolization was performed for 10 unruptured intracranial aneurysms. The sensor adequately recorded the force, and it reflected the operators' usual clinical experience. The presence of the sensor did not affect the procedures. The sensor enabled the operators to objectively note and evaluate the insertion force and better cooperative handling was possible. Additionally, other members of the intervention team shared the information. Force records demonstrated the characteristic patterns according to every stage of coiling (framing, filling, and finishing). The force sensor system adequately measured coil insertion force in intracranial aneurysm coil embolization procedures. The safety of this sensor was demonstrated in clinical application for the limited number of patients. This system is useful adjunct for assisting during coil embolization for an intracranial aneurysm. Copyright © 2017 Elsevier Inc. All rights reserved.

  6. Ripple reduction with magnetic inserts and saddle coils

    Energy Technology Data Exchange (ETDEWEB)

    Ane, J.M. [Association Euratom-CEA pour la Fusion, Dept. de Recherches sur la Fusion Controlee, Centre d`Etudes de Cadarache, 13 - Saint Paul-lez-Durance (France)

    1995-12-31

    Analytic formulas for the computation of the toroidal field ripple in a tokamak with saddle coils and/or magnetic inserts for the reduction of the ripple are derived. The results of these analytic formulas compare well with the results of a 3D magneto static code for the geometry of Tore Supra and ITER. In Tore Supra 72 saddle coils with 5% of the toroidal field coils current or 36 magnetic inserts 12 cm thick are needed to reduce by a factor of four the ripple in the outboard region of the plasma. In ITER, using ferromagnetic rather than austenitic balls in the space between the vacuum vessel skins, would partially offset the ripple-increasing effect due to the reduction of the number of TF coils from 24 to 20. (orig.).

  7. Ripple reduction with magnetic inserts and saddle coils

    Energy Technology Data Exchange (ETDEWEB)

    Ane, J.M. [Association Euratom-CEA, Centre d`Etudes de Cadarache, 13 - Saint-Paul-lez-Durance (France). Dept. de Recherches sur la Fusion Controlee

    1994-12-31

    Analytic formulas for the computation of the toroidal field ripple in a tokamak with saddle coils and/or magnetic inserts for the reduction of the ripple are derived. The results of these analytic formulas compare well with the results of a 3D magneto static code for the geometry of Tore Supra and ITER. In Tore Supra 72 saddle coils with 5% of the toroidal field coils current or 36 magnetic inserts 12 cm thick are needed to reduce by a factor of four the ripple in the outboard region of the plasma. In ITER, using ferromagnetic rather than austenitic balls in the space between the vacuum vessel skins, would partially offset the ripple-increasing effect due to the reduction of the number of TF coils from 24 to 20. (author) 4 refs., 9 figs.

  8. One century of Kirschner wires and Kirschner wire insertion techniques : A historical review

    NARCIS (Netherlands)

    Franssen, Bas B. G. M.; Schuurman, Arnold H.; Van der Molen, Aebele Mink; Kon, Moshe

    A century ago, in 1909, Martin Kirschner (1879-942) introduced a smooth pin, presently known as the Kirschner wire (K-wire). The K-wire was initiallly used for skeletal traction and is now currently used for many different goals. The development of the K-wire and its insertion devices were mainly

  9. Scalable Nernst thermoelectric power using a coiled galfenol wire

    Directory of Open Access Journals (Sweden)

    Zihao Yang

    2017-09-01

    Full Text Available The Nernst thermopower usually is considered far too weak in most metals for waste heat recovery. However, its transverse orientation gives it an advantage over the Seebeck effect on non-flat surfaces. Here, we experimentally demonstrate the scalable generation of a Nernst voltage in an air-cooled metal wire coiled around a hot cylinder. In this geometry, a radial temperature gradient generates an azimuthal electric field in the coil. A Galfenol (Fe0.85Ga0.15 wire is wrapped around a cartridge heater, and the voltage drop across the wire is measured as a function of axial magnetic field. As expected, the Nernst voltage scales linearly with the length of the wire. Based on heat conduction and fluid dynamic equations, finite-element method is used to calculate the temperature gradient across the Galfenol wire and determine the Nernst coefficient. A giant Nernst coefficient of -2.6 μV/KT at room temperature is estimated, in agreement with measurements on bulk Galfenol. We expect that the giant Nernst effect in Galfenol arises from its magnetostriction, presumably through enhanced magnon-phonon coupling. Our results demonstrate the feasibility of a transverse thermoelectric generator capable of scalable output power from non-flat heat sources.

  10. Scalable Nernst thermoelectric power using a coiled galfenol wire

    Science.gov (United States)

    Yang, Zihao; Codecido, Emilio A.; Marquez, Jason; Zheng, Yuanhua; Heremans, Joseph P.; Myers, Roberto C.

    2017-09-01

    The Nernst thermopower usually is considered far too weak in most metals for waste heat recovery. However, its transverse orientation gives it an advantage over the Seebeck effect on non-flat surfaces. Here, we experimentally demonstrate the scalable generation of a Nernst voltage in an air-cooled metal wire coiled around a hot cylinder. In this geometry, a radial temperature gradient generates an azimuthal electric field in the coil. A Galfenol (Fe0.85Ga0.15) wire is wrapped around a cartridge heater, and the voltage drop across the wire is measured as a function of axial magnetic field. As expected, the Nernst voltage scales linearly with the length of the wire. Based on heat conduction and fluid dynamic equations, finite-element method is used to calculate the temperature gradient across the Galfenol wire and determine the Nernst coefficient. A giant Nernst coefficient of -2.6 μV/KT at room temperature is estimated, in agreement with measurements on bulk Galfenol. We expect that the giant Nernst effect in Galfenol arises from its magnetostriction, presumably through enhanced magnon-phonon coupling. Our results demonstrate the feasibility of a transverse thermoelectric generator capable of scalable output power from non-flat heat sources.

  11. Implementation of a planar coil of wires as a sinus-galvanometer. Analysis of the coil magnetic field

    CERN Document Server

    Stoyanov, Dimitar G

    2010-01-01

    The paper presents a theoretical analysis on the interaction between the Earth's magnetic field of a compass needle and the magnetic field of a straight infinite current-carrying wire. Implementation of a planar horizontal coil of wires has been shown as a sinus galvanometer. The magnetic field over the planar coil of wires has been examined by experiment. The coil could be used as a model for straight infinite current wire in demonstration set-ups or could be given as an assignment in Physics laboratory workshops.

  12. ITER CS Model Coil and CS Insert Test Results

    Energy Technology Data Exchange (ETDEWEB)

    Martovetsky, N; Michael, P; Minervina, J; Radovinsky, A; Takayasu, M; Thome, R; Ando, T; Isono, T; Kato, T; Nakajima, H; Nishijima, G; Nunoya, Y; Sugimoto, M; Takahashi, Y; Tsuji, H; Bessette, D; Okuno, K; Ricci, M

    2000-09-07

    The Inner and Outer modules of the Central Solenoid Model Coil (CSMC) were built by US and Japanese home teams in collaboration with European and Russian teams to demonstrate the feasibility of a superconducting Central Solenoid for ITER and other large tokamak reactors. The CSMC mass is about 120 t, OD is about 3.6 m and the stored energy is 640 MJ at 46 kA and peak field of 13 T. Testing of the CSMC and the CS Insert took place at Japan Atomic Energy Research Institute (JAERI) from mid March until mid August 2000. This paper presents the main results of the tests performed.

  13. In vivo field-cycling relaxometry using an insert coil for magnetic field offset.

    Science.gov (United States)

    Pine, Kerrin J; Goldie, Fred; Lurie, David J

    2014-11-01

    The T(1) of tissue has a strong dependence on the measurement magnetic field strength. T(1) -dispersion could be a useful contrast parameter, but is unavailable to clinical MR systems which operate at fixed magnetic field strength. The purpose of this work was to implement a removable insert magnet coil for field-cycling T(1) -dispersion measurements on a vertical-field MRI scanner, by offsetting the static field over a volume of interest. An insert magnet coil was constructed for use with a whole-body sized 59 milli-Tesla (mT) vertical-field, permanent-magnet based imager. The coil has diameter 38 cm and thickness 6.1 cm and a homogeneous region (± 5%) of 5 cm DSV, offset by 5 cm from the coil surface. Surface radiofrequency (RF) coils were also constructed. The insert coil was used in conjunction with a surface RF coil and a volume-localized inversion-recovery pulse sequence to plot T(1) -dispersion in a human volunteer's forearm over a range of field strengths from 1 mT to 70 mT. T(1) -dispersion measurements were demonstrated on a fixed-field MRI scanner, using an insert coil. This demonstrates the feasibility of relaxation dispersion measurements on an otherwise conventional MR imager, facilitating the exploitation of T(1) -dispersion contrast for enhanced diagnosis. Copyright © 2013 Wiley Periodicals, Inc.

  14. Nonlinear Behavior of a Shim Coil in an LTS/HTS NMR Magnet With an HTS Insert Comprising Double-Pancake HTS-Tape Coils

    Science.gov (United States)

    Hahn, Seung-yong; Ahn, Min Cheol; Bascuñán, Juan; Yao, Weijun; Iwasa, Yukikazu

    2010-01-01

    This paper reports results, experimental and analytical, of the nonlinear behavior of a shim coil in the presence of an HTS coil assembled with double-pancake (DP) HTS-tape coils. The experimental results are from: 1) operation of a 700 MHz LTS/HTS NMR magnet (LH700) consisting of a 600 MHz LTS NMR magnet (L600) equipped with superconducting shim coils and a 100 MHz DP-assembled HTS insert (H100) and; 2) an experiment with a room-temperature (RT) Z1 shim coil coupled to a 50 MHz DP-as-sembled HTS insert (H50). A field mapping theory with a harmonic analysis is applied to interpret both results. Based on experimental results and analyses, we conclude that the screening-current-induced field (SCF) generated by a DP-assembled HTS insert is primarily responsible for the nonlinear behavior, including strength degradation, of a shim coil. PMID:20383282

  15. Kirschner Wires : insertion techniques and bone related consequences

    NARCIS (Netherlands)

    Franssen, B.B.G.M.

    2010-01-01

    The Kirschner (K-) wire was first introduced in 1909 by Martin Kirschner. This is a thin unthreaded wire of surgical steel with a diameter of up to three millimeters and a selection of different tips. The use of K-wires is often promoted as a simple technique because of its easy placement,

  16. Loss of Guide Wire: A Rare Complication of Intra-Aortic Balloon Pump Insertion

    Directory of Open Access Journals (Sweden)

    Manouchehr Hekmat

    2015-10-01

    Full Text Available At the final stages of a coronary artery bypass graft operation on a 64-year-old man, an experienced physician attempted to insert an intra-aortic balloon pump into the femoral artery via the Seldinger technique. However, while the balloon pump was being passed over the guide wire, the latter was completely lost.The guide wire should be held at the tip at all times to prevent passage into the vessel. Strict adherence to this rule will prevent guide-wire loss, which is, albeit rare and completely avoidable, a potentially life-threatening complication of central vein or artery catheterization, with reported fatality rates of up to 20% when the whole wire is lost. The literature contains several reports on guide-wire loss during central venous, arterial, and hemodialysis catheterization, but we report for the first time the loss of a guide wire as a rare complication of intra-aortic balloon pump insertion.

  17. Coil embolization of internal mammary artery injured during central vein catheter and cardiac pacemaker lead insertion

    Energy Technology Data Exchange (ETDEWEB)

    Chemelli, A.P. [Department of Radiology, Innsbruck Medical University, Anichstrasse 35, 6020 Innsbruck (Austria)], E-mail: Andreas.Chemelli@i-med.ac.at; Chemelli-Steingruber, I.E. [Department of Radiology, Innsbruck Medical University, Anichstrasse 35, 6020 Innsbruck (Austria); Bonaros, N. [Department of Cardiovascular Surgery, Innsbruck Medical University (Austria); Luckner, G. [Department of Anaesthesiology and Critical Care Medicine, Innsbruck Medical University (Austria); Millonig, G. [Department of Gastroenterology and Hepatology, Innsbruck Medical University (Austria); Seppi, K. [Department of Neurology, Innsbruck Medical University (Austria); Lottersberger, C.; Jaschke, W. [Department of Radiology, Innsbruck Medical University, Anichstrasse 35, 6020 Innsbruck (Austria)

    2009-08-15

    Purpose: This study describes several cases of endovascular coil embolization of the proximal internal mammary artery injured by blind approach to the subclavian vein for central venous catheter or pacemaker lead insertion. Materials and methods: We conducted a retrospective analysis of five patients with iatrogenic arterial lesions of the internal mammary artery (IMA). The lesions occurred in three patients from a puncture of the subclavian vein during insertion of a central venous catheter and in two patients from a puncture of the subclavian vein for insertion of a pacemaker lead. Four patients had acute symptoms of bleeding with mediastinal hematoma and hematothorax and one patient was investigated in a chronic stage. A pseudoaneurysm was detected in all five patients. All four acute and hemodynamic unstable patients required hemodynamic support. Results: In all patients, embolization was performed using a coaxial catheter technique, and a long segment of the IMA adjacent distally and proximally to the source of bleeding was occluded with pushable microcoils. In one patient, additional mechanically detachable microcoils were used at the very proximal part of the IMA. Microcoil embolization of the IMA was successful in all patients, and the source of bleeding was eliminated in all patients. Conclusion: Transarterial coil embolization is a feasible and efficient method in treating acute bleeding and pseudoaneurysm of the IMA and should be considered if mediastinal hematoma or hemathorax occurs after blind puncture of the subclavian vein.

  18. First Test Results on ITER CS Model Coil and CS Insert

    Energy Technology Data Exchange (ETDEWEB)

    Martovetsky, N; Michael, P; Minervini, J; Radovinsky, A; Takayasu, M; Thome, R; Ando, T; Isono, T; Kato, T; Nakajima, H; Nishijima, G; Nunoya, Y; Sugimoto, M; Takahashi, Y; Tsuji, H; Bessette, D; Okuno, K; Ricci, M; Maix, R

    2000-10-12

    The Inner and Outer modules of the Central Solenoid Model Coil (CSMC) were built by US and Japanese home teams in collaboration with European and Russian teams to demonstrate the feasibility of a superconducting Central Solenoid for ITER and other large tokamak reactors. The CSMC mass is about 120 t, OD is about 3.6 m and the stored energy is 640 MJ at 46 kA and peak field of 13 T. Testing of the CSMC and the CS Insert took place at the Japan Atomic Energy Research Institute (JAERI) from mid March until mid August 2000. This paper presents the main results of the tests performed.

  19. Coil tubing fishing operations utilize a first time technique to strip over and recover 9500 feet of stuck slickline wire

    Energy Technology Data Exchange (ETDEWEB)

    Forgenie, V.H.; Heiberger, E.M.; Kelso, L.K. [and others

    1995-12-31

    Coil tubing was utilized to perform a modified strip over operation and recover 9500 ft. of stuck slickline (0.108 in.) wire. The technique, thought to be an industry first, eliminated the risky option of recovering the wire piecemeal via conventional wireline fishing operations. This paper documents the background that lead to the development of the technique. An operational summary details its implementation and illustrations are included of the special tools and techniques employed.

  20. Progress of the insert coil for the US-NHMFL 100 T multi-shot pulse magnet

    Science.gov (United States)

    Swenson, C. A.; Marshall, W. S.; Gavrilin, A. V.; Han, K.; Schillig, J.; Sims, J. R.; Schneider-Muntau, H. J.

    2004-04-01

    We review insert development for the US-NHMFL 100 T non-destructive short-pulse magnet program. Coil electro-mechanics are presented in the context of the selected materials: CuNb conductor, PBO zylon-fibre, and MP35N, a cobalt-based super-alloy, reinforcement. We present the results of conductor cyclic fatigue testing and explore the data's ramifications. We present the coil geometry, and a new “poly-layer” assembly technique. We review the structure of our small coil test program to evaluate the engineering and materials design.

  1. Progress of the insert coil for the US-NHMFL 100 T multi-shot pulse magnet

    Energy Technology Data Exchange (ETDEWEB)

    Swenson, C.A.; Marshall, W.S.; Gavrilin, A.V.; Han, K.; Schillig, J.; Sims, J.R.; Schneider-Muntau, H.J

    2004-04-30

    We review insert development for the US-NHMFL 100 T non-destructive short-pulse magnet program. Coil electro-mechanics are presented in the context of the selected materials: CuNb conductor, PBO zylon-fibre, and MP35N, a cobalt-based super-alloy, reinforcement. We present the results of conductor cyclic fatigue testing and explore the data's ramifications. We present the coil geometry, and a new 'poly-layer' assembly technique. We review the structure of our small coil test program to evaluate the engineering and materials design.

  2. Study on the Persistent Current Switch in HTS Coils Wound with 2G Wire for Compact NMR Magnets

    Science.gov (United States)

    Sugo, K.; Kim, S. B.; Nomura, R.; Ueda, H.

    2017-07-01

    High temperature superconducting (HTS) magnets wound with REBCO wires are used in many applications, and the superconducting magnet which is operated in persistent current mode has many advantages. Therefore, we have been developing compact NMR relaxometry devices using HTS coils operated at liquid nitrogen temperature. The required strength and homogeneity of magnetic field of proposed NMR relaxometry devices are 1.5 T and 150 ppm/cm3 respectively. The proposed HTS magnet for NMR relaxometry device consists with stacked HTS double pancake coils wound with REBCO wires and operated by persistent current mode (PCM) using superconducting joint between REBCO wires. In PCM operation, the ability of persistent current switch (PCS) is very important, so, in this study, the thermal properties of YBCO wire against the various thermal inputs by heater were investigated experimentally to design the PCS for PCM HTS magnets. The thermal behaviors of the YBCO wires were measured as functions of amount of heat input using two types of epoxy resin. The current bypassing properties on the YBCO loop coil with developed PCS were studied experimentally.

  3. Enhancing electron transport in molecular wires by insertion of a ferrocene center.

    Science.gov (United States)

    Sun, Yan-Yan; Peng, Zheng-Lian; Hou, Rong; Liang, Jing-Hong; Zheng, Ju-Fang; Zhou, Xiao-Yi; Zhou, Xiao-Shun; Jin, Shan; Niu, Zhen-Jiang; Mao, Bing-Wei

    2014-02-14

    We have determined the conductance of alkane-linked ferrocene molecules with carboxylic acid anchoring groups using the STM break junction technique, and three sets of conductance values were found, i.e. high conductance (HC), medium conductance (MC) and low conductance (LC) values. The enhancing effect of the incorporated ferrocene on the electron transport in saturated alkane molecular wires is demonstrated by the increased conductance of the ferrocene molecules, attributed to the reduction of the tunneling barrier and the HOMO-LUMO gap induced by the insertion of ferrocene. Furthermore, the electron-withdrawing carbonyl group on the unconjugated backbone has little or no influence on single-molecule conductance. The current work provides a feasible approach for the design of high-performance molecular wires.

  4. Microfabricated inserts for magic angle coil spinning (MACS wireless NMR spectroscopy.

    Directory of Open Access Journals (Sweden)

    Vlad Badilita

    Full Text Available This article describes the development and testing of the first automatically microfabricated probes to be used in conjunction with the magic angle coil spinning (MACS NMR technique. NMR spectroscopy is a versatile technique for a large range of applications, but its intrinsically low sensitivity poses significant difficulties in analyzing mass- and volume-limited samples. The combination of microfabrication technology and MACS addresses several well-known NMR issues in a concerted manner for the first time: (i reproducible wafer-scale fabrication of the first-in-kind on-chip LC microresonator for inductive coupling of the NMR signal and reliable exploitation of MACS capabilities; (ii improving the sensitivity and the spectral resolution by simultaneous spinning the detection microcoil together with the sample at the "magic angle" of 54.74° with respect to the direction of the magnetic field (magic angle spinning - MAS, accompanied by the wireless signal transmission between the microcoil and the primary circuit of the NMR spectrometer; (iii given the high spinning rates (tens of kHz involved in the MAS methodology, the microfabricated inserts exhibit a clear kinematic advantage over their previously demonstrated counterparts due to the inherent capability to produce small radius cylindrical geometries, thus tremendously reducing the mechanical stress and tearing forces on the sample. In order to demonstrate the versatility of the microfabrication technology, we have designed MACS probes for various Larmor frequencies (194, 500 and 700 MHz testing several samples such as water, Drosophila pupae, adamantane solid and LiCl at different magic angle spinning speeds.

  5. Analysis of the ITER central solenoid insert (CSI) coil stability tests

    Science.gov (United States)

    Savoldi, L.; Bonifetto, R.; Breschi, M.; Isono, T.; Martovetsky, N.; Ozeki, H.; Zanino, R.

    2017-07-01

    At the end of the test campaign of the ITER Central Solenoid Insert (CSI) coil in 2015, after 16,000 electromagnetic (EM) cycles, some tests were devoted to the study of the conductor stability, through the measurement of the Minimum Quench Energy (MQE). The tests were performed by means of an inductive heater (IH), located in the high-field region of the CSI and wrapped around the conductor. The calorimetric calibration of the IH is presented here, aimed at assessing the energy deposited in the conductor for different values of the IH electrical operating conditions. The MQE of the conductor of the ITER CS module 3L can be estimated as ∼200 J ± 20%, deposited on the whole conductor on a length of ∼10 cm (the IH length) in ∼40 ms, at current and magnetic field conditions relevant for the ITER CS operation. The repartition of the energy deposited in the conductor under the IH is computed to be ∼10% in the cable and 90% in the jacket by means of a 3D Finite Elements EM model. It is shown how this repartition implies that the bundle (cable + helium) heat capacity is fully available for stability on the time scale of the tested disturbances. This repartition is used in input to the thermal-hydraulic analysis performed with the 4C code, to assess the capability of the model to accurately reproduce the stability threshold of the conductor. The MQE computed by the code for this disturbance is in good agreement with the measured value, with an underestimation within 15% of the experimental value.

  6. Correlation between extension-block K-wire insertion angle and postoperative extension loss in mallet finger fracture.

    Science.gov (United States)

    Lee, S K; Kim, Y H; Moon, K H; Choy, W S

    2017-10-09

    Extension-block pinning represents a simple and reliable surgical technique. Although this procedure is commonly performed successfully, some patients develop postoperative extension loss. To date, the relationship between extension-block Kirschner wire (K-wire) insertion angle and postoperative extension loss in mallet finger fracture remains unclear. We aimed to clarify this relationship and further evaluate how various operative and non-operative factors affect postoperative extension loss after extension-block pinning for mallet finger fracture. A retrospective study was conducted to investigate a relationship between extension block K-wire insertion angle and postoperative extension loss. The inclusion criteria were: (1) a dorsal intra-articular fracture fragment involving 30% of the base of the distal phalanx with or without volar subluxation of the distal phalanx; and (2) angle and fixation angle of the distal interphalangeal (DIP) joint were assessed using lateral radiograph at immediate postoperative time. Postoperative extension loss was assessed by using lateral radiograph at latest follow-up. Extension-block K-wire insertion angle was defined as the acute angle between extension block K-wire and longitudinal axis of middle phalangeal head. DIP joint fixation angle was defined as the acute angle between the distal phalanx and middle phalanx longitudinal axes. Seventy-five patients were included. The correlation analysis revealed that extension-block K-wire insertion angle had a negative correlation with postoperative extension loss, whereas fracture size and time to operation had a positive correlation (correlation coefficient for extension block K-wire angle: -0.66, facture size: +0.67, time to operation: +0.60). When stratifying patients in terms of negative and positive fixation angle of the DIP joint, the independent t-test showed that mean postoperative extension loss is -3.67° and +4.54° (DIP joint fixation angles of angle (30°, 30°-40°, >40

  7. Short echo time proton spectroscopy of the brain in healthy volunteers using an insert gradient head coil

    DEFF Research Database (Denmark)

    Gideon, P; Danielsen, E R; Schneider, M

    1995-01-01

    An insert gradient head coil with built-in X, Y, and Z gradients was used for localized proton spectroscopy in the brain of healthy volunteers, using short echo time stimulated echo acquisition mode (STEAM) sequences. Volume of interest size was 3.4 ml, repetition time was 6.0 s, and echo times w....../glutamate and myo-inositols. These compounds were more prominent within grey matter than within white matter. Rough estimations of metabolite concentrations using water as an internal standard were in good agreement with previous reports....

  8. A new technique to prevent curling of guide wire in urinary bladder during J stent insertion with flexible cystoscope.

    Science.gov (United States)

    Mahmood, Nasir; Pasha, Tahir

    2016-01-01

    Insertion of J stent is a very common procedure performed by urologists. This procedure is often performed to relieve ureteral obstruction due to stones, tumours, ureteral kink, or stricture on urgent basis. An increasing number of urologists are using a flexible cystoscope and local anaesthetic for J stent insertion. Occasionally, the guide wire curls in the bladder, making it impossible to insert the J stent. Here, we describe a simple method to overcome this problem using modified ureteral dilator, which is usually available in the cystoscopy suite.

  9. Screening current induced magnetic field in REBCO superconducting coil wound by using split wire having intermittent inner split

    Science.gov (United States)

    Matsuda, Tetsuro; Jin, Xinzhe; Okamura, Tetsuji

    2017-09-01

    REBCO-coated conductor having a high critical current is promising for applications in next generation apparatuses such as ultra-high field NMR, high-resolution MRI, and high-precision accelerator. However, it has an important challenge for application in NMR and MRI, due to the single core in REBCO superconducting layer. The single core induces a large screening current-induced magnetic field (screening current field), and it influences the controlling of center field in NMR/MRI magnet. To reduce the screening current field, we have recently developed a split wire having multi-core structure by inner split method (electrical separation by bending stress, ESBS). In experiment, short samples with linear inner split by a large bending stress of 80 N were prepared and tested. However, to fabricate a long length wire with good quality, it is better to use a smaller bending stress. In this study, a low-bending-stress inner split method is used to fabricate superconducting tapes with longitudinal split in their superconducting layer. The fabrication and experimental assessments for the wire and coil are carried out.

  10. Superconducting Quadrupoles for the ISR High Luminosity insertion Coil cross section

    CERN Multimedia

    1978-01-01

    This picture shows a cut out section of an ISR High Luminosity (low beta) Quadrupole. One can clearly see the distribution of conductors and spacers which produces the wanted quadrupolar field. The spacers are made of pure copper and the central pole of stainless steel.The superconducting wire may be seen in photo 8008591X. See also pictures 7702690X, 8008591X, 7702698X.

  11. A High-Sensitivity Current Sensor Utilizing CrNi Wire and Microfiber Coils

    Directory of Open Access Journals (Sweden)

    Xiaodong Xie

    2014-05-01

    Full Text Available We obtain an extremely high current sensitivity by wrapping a section of microfiber on a thin-diameter chromium-nickel wire. Our detected current sensitivity is as high as 220.65 nm/A2 for a structure length of only 35 μm. Such sensitivity is two orders of magnitude higher than the counterparts reported in the literature. Analysis shows that a higher resistivity or/and a thinner diameter of the metal wire may produce higher sensitivity. The effects of varying the structure parameters on sensitivity are discussed. The presented structure has potential for low-current sensing or highly electrically-tunable filtering applications.

  12. Modelling of coil-loaded wire antenna using composite multiple domain basis functions

    CSIR Research Space (South Africa)

    Lysko, AA

    2010-03-01

    Full Text Available - tional Electromagnetics, Artech House, 2001. 3. Rogers, S. D. and C. M. Butler, \\An e–cient curved-wire integral equation solution technique," IEEE Trans. Ant. and Propag., 70{79, Vol. 49, Jan. 2001. 4. Mosig, J. and E. Suter, \\A multilevel divide.... 8. Wan, J. X., J. Lei, and C.-H. Liang, \\An e–cient analysis of large-scale periodic microstrip antenna arrays using the characteristic basis function method," Progress In Electromagnetics Research, PIER 50, 61{81, 2005. 9. Taguchi, M., K...

  13. The Laser Welding with Hot Wire of 316LN Thick Plate Applied on ITER Correction Coil Case

    CERN Document Server

    Fang, Chao; Wu, Weiyue; Wei, Jing; Zhang, Shuquan; Li, Hongwei; Dolgetta, N; Libeyre, P; Cormany, C; Sgobba, S

    2014-01-01

    ITER correction coil (CC) cases have characteristics of small cross section, large dimensions, and complex structure. The cases are made of heavy thick (20 mm), high strength and high toughness austenitic stainless steel 316LN. The multi-pass laser welding with hot wire technology is used for the case closure welding, due to its low heat input and deformation. In order to evaluate the reliability of this welding technology, 20 mm welding samples with the same groove structure and welding depth as the cases were welded. High purity argon was used as the shielding gas to prevent oxidation because of the narrowness and depth of the weld. In this paper investigation of, microstructure characteristics and mechanical properties of welded joints using optimized welding parameters are presented. The results show that the base metal, fusion metal, and heat affected zone (HAZ) are all have fully austenitic microstructure, and that the grain size of fusion metal was finer than that of the base metal. The welding resulte...

  14. Does the insertion of more than one wire allow successful excision of large clusters of malignant calcification?

    Energy Technology Data Exchange (ETDEWEB)

    Cordiner, C.M.; Litherland, J.C.; Young, I.E

    2006-08-15

    AIM: To determine whether the insertion of more than one localization wire for larger areas of malignant microcalcification reduces the need for re-excision. METHOD: This is a retrospective study of 101 cases of malignant calcifications preoperatively marked by one or more wires. Surgical and histopathology data were obtained from hospital records. Mammograms and specimen radiographs were evaluated without knowledge of the eventual outcome, i.e., whether further surgery was required or not. All cases had a preoperative diagnosis of malignancy. RESULT: In this study the group of patients in which two or more wires were inserted had mammographically larger lesions (p < 0.000001) but did not have a greater chance of needing re-excision (p = 0.822). Mammograms that demonstrated flecks of microcalcification outlying the main cluster were also more likely to require further surgery (p < 0.01). Calcifications associated with high-grade ductal carcinoma in situ (DCIS) had three times the risk of requiring further surgery (p < 0.01). However, as reported in other studies re-excision was not related to breast size (p = 0.63) [Kollias J, Gill PG, Beamond B, Rossi H, Langlois S, Vernon-Roberts E. Clinical and radiological predictors of complete excision in breast-conserving surgery for primary breast cancer. Aust N Z J Surg 1998;68:702-6]. CONCLUSION: It was previously suggested that the risk of re-excision for DCIS is related to the size of the initial lesion [Cheng L, Al-Kaisi NK, Gordon NH, Liu AY, Gebrail F, Shenk RR. Relationship between the size and margins of ductal carcinoma in situ of the breast and residual disease. J Nat Cancer Inst 1997;89:1356-60]. However, in the present study larger clusters of microcalcification that have been 'bracketed' by two or more wires do not appear to have a greater requirement for re-excision. Grading of the malignant microcalcifications preoperatively may encourage the surgeon to take a wider margin. Careful examination of

  15. High field Nb/sub 3/Sn Axicell insert coils for the Mirror Fusion Test Facility-B (MFTF-B) axicell configuration. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Baldi, R.W.; Tatro, R.E.; Scanlan, R.M.; Agarwal, K.L.; Bailey, R.E.; Burgeson, J.E.; Kim, I.K.; Magnuson, G.D.; Mallett, B.D.; Pickering, J.L.

    1984-03-01

    Two 12-tesla superconducting insert coils are being designed by General Dynamics Convair Division for the axicell regions of MFTF-B for Lawrence Livermore National Laboratory. A major challenge of this project is to ensure that combined fabrication and operational strains induced in the conductor are within stringent limitations of the relatively brittle Nb/sub 3/Sn superconductor filaments. These coils are located in the axicell region of MFTF-B. They have a clear-bore diameter of 36.195cm (14.25 inches) and consist of 27 double pancakes (i.e., 54 pancakes per coil) would on an electrically insulated 304LN stainless steel/bobbin helium vessel. Each pancake has 57 turns separated by G-10CR insulation. The complete winding bundle has 4.6 million ampere-turns and uniform current density of 2007 A/cm/sup 2/. In conjunction with the other magnets in the system, they produce a 12-tesla central field and a 12.52-tesla peak field. A multifilamentary Nb/sub 3/Sn conductor was selected to meet these requirements. The conductor consists of a monolithic insert soldered into a copper stabilizer. Sufficient cross-sectional area and work-hardening of the copper stabilizer has been provided for the conductor to self-react the electromagnetic Lorentz force induced hoop stresses with normal operational tensile strains less than 0.07 percent.

  16. Use of Flexible Cystoscopy to Insert a Foley Catheter over a Guide Wire in Spinal Cord Injury Patients: Special Precautions to be Observed

    Directory of Open Access Journals (Sweden)

    Subramanian Vaidyanathan

    2011-01-01

    Full Text Available When urethral catheterisation is difficult or impossible in spinal cord injury patients, flexible cystoscopy and urethral catheterisation over a guide wire can be performed on the bedside, thus obviating the need for emergency suprapubic cystostomy. Spinal cord injury patients, who undergo flexible cystoscopy and urethral catheterisation over a guide wire, may develop potentially serious complications. (1 Persons with lesion above T-6 are susceptible to develop autonomic dysreflexia during cystoscopy and urethral catheterisation over a guide wire; nifedipine 5–10 milligrams may be administered sublingually just prior to the procedure to prevent autonomic dysreflexia. (2 Spinal cord injury patients are at increased risk for getting urine infections as compared to able-bodied individuals. Therefore, antibiotics should be given to patients who get haematuria or urethral bleeding following urethral catheterisation over a guide wire. (3 Some spinal cord injury patients may have a small capacity bladder; in these patients, the guide wire, which is introduced into the urinary bladder, may fold upon itself with the tip of guide wire entering the urethra. If this complication is not recognised and a catheter is inserted over the guide wire, the Foley catheter will then be misplaced in urethra despite using cystoscopy and guide wire.

  17. Measurement of a Conduction Cooled Nb3Sn Racetrack Coil

    Science.gov (United States)

    Kim, HS; Kovacs, C.; Rochester, J.; Sumption, MD; Tomsic, M.; Peng, X.; Doll, D.

    2017-12-01

    Use of superconducting coils for wind turbines and electric aircraft is of interest because of the potential for high power density and weight reduction. Here we test a racetrack coil developed as a proof-of-concept for cryogen-free superconducting motors and generators. The coil was wound with 1209 m of 0.7-mm-diameter insulated tube-type Nb3Sn wire. The coil was epoxy-impregnated, instrumented, covered with numerous layers of aluminized mylar insulation, and inserted vertically into a dewar. The system was cooled to 4.2 K, and a few inches of liquid helium was allowed to collect at the bottom of the dewar but below the coil. The coil was cooled by conduction via copper cooling bars were attached to the coil but also were immersed in the liquid helium at their lower ends. Several current tests were performed on the coil, initially in voltage mode, and one run in current mode. The maximum coil Ic at 4.2 K was 480 A, generating 3.06 T at the surface of the coil. The coil met the design targets with a noticeable margin.

  18. Experimenting with wires, batteries, bulbs and the induction coil: Narratives of teaching and learning physics in the electrical investigations of Laura, David, Jamie, myself and the nineteenth century experimenters. Our developments and instruments

    Science.gov (United States)

    Cavicchi, Elizabeth Mary

    Physics is conventionally taught as a fixed curriculum which students must master. This thesis changes that: curriculum emerges from what learners try and question in experiments they invent. The thesis narrates: three adult students exploring wires, batteries and bulbs with me as teacher; nineteenth century investigations of electromagnetism; my laboratory work replicating historic instruments. In each case, learning arose through activity with materials. Evidences of this are analyzed within narratives and reflections. I used teaching-research, a method developed by Duckworth from Piaget's clinical interviewing, to research and simultaneously extend students' evolving understandings. What I learned through questioning students informed my next interactions; what they learned extended their experimenting. Similarly, I researched historical accounts interactively: improvising experiments to develop my understandings. Studying my own learning deepened my interpretations of students' learning. My students Laura, David and Jamie experimented by: soldering bulbs to wires, making series and parallel circuits, inserting resistive wire that dimmed bulbs, conducting electricity through salt water They noticed bulb brightness and battery heat, compared electricity's paths, questioned how voltage and current relate. They inferred electricity's effects manifest magnitudes of material properties. They found their experiences while learning were inseparable from what they learned. I researched investigations connected with Cavendish's leather fish, Galvani's frogs, Schweigger's wire spiraled around a compass needle, Henry's electromagnets, Faraday's induction ring, induction devices of Page, Callan, Hearder. Experimentally, I made galvanometers, electromagnets, induction rings, induction coil. I observed effects of electromagnetism, internal resistance, induced sparking. Across these investigations, learning developed with instrumental innovations; confusions were productive

  19. LHC bending magnet coil

    CERN Multimedia

    A short test version of coil of wire used for the LHC dipole magnets. The high magnetic fields needed for guiding particles around the Large Hadron Collider (LHC) ring are created by passing 12’500 amps of current through coils of superconducting wiring. At very low temperatures, superconductors have no electrical resistance and therefore no power loss. The LHC is the largest superconducting installation ever built. The magnetic field must also be extremely uniform. This means the current flowing in the coils has to be very precisely controlled. Indeed, nowhere before has such precision been achieved at such high currents. Magnet coils are made of copper-clad niobium–titanium cables — each wire in the cable consists of 9’000 niobium–titanium filaments ten times finer than a hair.

  20. Does the insertion of a gel-based marker at stereotactic breast biopsy allow subsequent wire localizations to be carried out under ultrasound guidance?

    Energy Technology Data Exchange (ETDEWEB)

    McMahon, M.A. [Nottingham Breast Institute, Nottingham City Hospital, Hucknall Road, Nottingham (United Kingdom); James, J.J., E-mail: jonathan.james@nuh.nhs.uk [Nottingham Breast Institute, Nottingham City Hospital, Hucknall Road, Nottingham (United Kingdom); Cornford, E.J.; Hamilton, L.J.; Burrell, H.C. [Nottingham Breast Institute, Nottingham City Hospital, Hucknall Road, Nottingham (United Kingdom)

    2011-09-15

    Aim: To investigate whether the insertion of a gel-based marker at the time of stereotactic breast biopsy allows subsequent preoperative localization to be performed under ultrasound guidance. Materials and methods: One hundred consecutive women who underwent either a 10 G stereotactic vacuum-assisted breast biopsy or 14 G stereotactic core biopsy with marker placement, followed by wire localization and surgical excision were identified. All had mammographic abnormalities not initially visible with ultrasound. The method of preoperative localization was recorded and its success judged with reference to the wire position on the post-procedure films relative to the mammographic abnormality and the marker. Histopathology data were reviewed to ensure the lesion had been adequately excised. Results: Eighty-three women (83%) had a successful ultrasound-guided wire localization. Successful ultrasound-guided localization was more likely after stereotactic vacuum biopsy (86%) compared to stereotactic core biopsy (68%), although this did not quite reach statistical significance (p = 0.06). Conclusion: The routine placement of a gel-based marker after stereotactic breast biopsy facilitates preoperative ultrasound-guided localization.

  1. Nylon screws make inexpensive coil forms

    Science.gov (United States)

    Aucoin, G.; Rosenthal, C.

    1978-01-01

    Standard nylon screws act as coil form copper wire laid down in spiral thread. Completed coil may be bonded to printed-circuit board. However, it is impossible to tune coil by adjusting spacing between windings, technique sometimes used with air-core coils.

  2. A novel technique for placement of sacro-alar-iliac (S2AI) screws by K-wire insertion using intraoperative navigation.

    Science.gov (United States)

    Phan, Kevin; Li, Julian; Giang, Gloria; Teng, Ian; Phan, Steven; Chang, Nicholas; Mobbs, Ralph

    2017-11-01

    Sacral-iliac fixation techniques may be indicated in the management of various lumbosacral pathologies including spinal degeneration, infection, tumour resection, fracture, pseudarthrosis, correction of spinal deformities involving long fusion constructs to the sacrum and cases with poor sacral fixation. There are a number of options for lumbosacral fixation each with their own advantages and disadvantages. Though S2-alar-iliac (S2AI) have demonstrated promising advantages over alternatives, the complex anatomy of the spinopelvic region demands precise insertion of the screws to create a biomechanically robust construct safely. As such, we present a novel technique of using intra-operative CT navigation and K-wires to establish and secure a planned trajectory, thereby ensuring solid spinopelvic fixation with S2AI screws. This was performed as part of a long fusion construct for correction of kyphosis deformity in a male patient. Copyright © 2017. Published by Elsevier Ltd.

  3. Development of the Current Bypassing Methods into the Transverse Direction in Non-insulation HTS Coils

    Science.gov (United States)

    Tanaka, K.; Kim, S. B.; Ikoma, H.; Kanemoto, D.

    In the case of motors and generators, the benefits of using high temperature superconducting (HTS) coils can be represented by the reduction of 50% in both losses and sizes compared to conventional machines. However, it is hard to establish quench detection and protection devices for the HTS coils applied to the rotors of motors and generators. So, the stability of the coils is lower than for the quiescent coils applied to NMR, MRI and so on. Therefore, it is important to improve the self-protection ability of HTS coils. We have studied the methods to improve the self-protection ability of HTS coils by removing the layer-to-layer insulation and inserting metal tape instead of the electrical insulation. The operating current in the non-insulated HTS coil was bypassed into the transverse direction by the generated normal region because of their electrical contact among the winding. In this study, we examined the method to control the current bypassing on layer-to-layer for controlling the inductance of the non-insulated HTS coil. The current bypassing properties on non-insulated HTS coil wound with 2G wires will be discussed.

  4. Tesla coil theoretical model and experimental verification

    OpenAIRE

    Voitkans, Janis; Voitkans, Arnis

    2014-01-01

    Abstract – In this paper a theoretical model of a Tesla coil operation is proposed. Tesla coil is described as a long line with distributed parameters in a single-wired format, where the line voltage is measured against electrically neutral space. It is shown that equivalent two-wired scheme can be found for a single-wired scheme and already known long line theory can be applied to a Tesla coil. Formulas for calculation of voltage in a Tesla coil by coordinate and calculation of resonance fre...

  5. Trapped field properties of a Y–Ba–Cu–O bulk by pulsed field magnetization using a split coil inserted by iron yokes with various geometries and electromagnetic properties

    Energy Technology Data Exchange (ETDEWEB)

    Takahashi, K., E-mail: t2216017@iwate-u.ac.jp [Department of Physical Science and Materials Engineering, Faculty of Science and Engineering, Iwate University, 4-3-5 Ueda, Morioka 020-8551 (Japan); Ainslie, M.D. [Bulk Superconductivity Group, Department of Engineering, University of Cambridge, Trumpington Street, Cambridge CB2 1PZ (United Kingdom); Fujishiro, H.; Naito, T. [Department of Physical Science and Materials Engineering, Faculty of Science and Engineering, Iwate University, 4-3-5 Ueda, Morioka 020-8551 (Japan); Shi, Y-H.; Cardwell, D.A. [Bulk Superconductivity Group, Department of Engineering, University of Cambridge, Trumpington Street, Cambridge CB2 1PZ (United Kingdom)

    2017-05-15

    Highlights: • The trapped field characteristics of a standard Y–Ba–Cu–O bulk magnetized by PFM was investigated using a split coil with three kinds of iron yokes inserted in the bores of coil,both experimentally and numerically. • Numerical results encourage better understanding of the role of yoke, including the typical behavior of the magnetic flux, such as a flux jump during PFM. • A higher saturation magnetic flux density of the yoke material was effective to reduce flux flow in the descending stage of the pulsed field. • A conductivity of the yoke material also acts to reduce the velocity of the flux intruding the bulk because of eddy currents that flow in the yoke that oppose the magnetization, which reduces the temperature rise in the bulk. - Abstract: We have investigated, both experimentally and numerically, the trapped field characteristics of a standard Y–Ba–Cu–O bulk of 30 mm in diameter and 14 mm in thickness magnetized by pulsed field magnetization (PFM) using a split coil, in which three kinds of iron yoke are inserted in the bore of the coil: soft iron with a flat surface, soft iron with a taper, and permendur (50Fe + 50Co alloy) with a flat surface. The highest trapped field, B{sub Tmax}, of 2.93 T was achieved at 40 K in the case of the permendur yoke, which was slightly higher than that obtained for the flat soft iron or the tapered soft iron yokes, and was much higher than 2.20 T in the case without the yoke. The insertion effect of the yoke on the trapped field characteristics was also investigated using numerical simulations. The results suggest that the saturation magnetic flux density, B{sub sat}, of the yoke acts to reduce the flux flow due to its hysteretic magnetization curve and the higher electrical conductivity, σ, of the yoke material also acts to suppress the flux increase rate. A flux jump (or flux leap) can be reproduced in the ascending stage of PFM using numerical simulation, using an assumption of relatively

  6. Calculations on resonance spin-echo coils

    CERN Document Server

    Prokudaylo, S B; Keller, T; Bleuel, M; Axtner, M; Selvachev, A

    2002-01-01

    The performance of the coils used for a resonance spin-echo spectrometer is simulated to obtain the optimum parameters. The possibility to use a round wire instead of a flat band for coil production is explored. The parameters of the static bootstrap coils were varied in a 2D approach and a better configuration than one actually uses was found. (orig.)

  7. Complete Obliteration of a Basilar Artery Aneurysm after Insertion of a Self- Expandable Leo Stent into the Basilar Artery without Coil Embolization

    Energy Technology Data Exchange (ETDEWEB)

    Juszkat, Robert; Nowak, Stanis Aw; Wieloch, Micha; Zarzecka, Anna [Poznan University of Medical Sciences, Poznan (Poland)

    2008-08-15

    We report a case of a 45-year-old man who underwent endovascular treatment in the acute setting of a subarachnoid hemorrhage due to rupture of a widenecked basilar trunk aneurysm. The patient was treated with stent implantation without coiling. A control angiographic scan obtained immediately after the procedure revealed significantly decreased intraaneurysmal flow. Follow-up angiography performed after one month demonstrated total aneurysm occlusion.

  8. Tesla Coil Theoretical Model and its Experimental Verification

    National Research Council Canada - National Science Library

    Janis Voitkans; Arnis Voitkans

    2014-01-01

    In this paper a theoretical model of Tesla coil operation is proposed. Tesla coil is described as a long line with distributed parameters in a single-wire form, where the line voltage is measured across electrically neutral space...

  9. Tie rod insertion test

    CERN Multimedia

    B. LEVESY

    2002-01-01

    The superconducting coil is inserted in the outer vaccum tank and supported by a set of tie rods. These tie rods are made of titanium alloy. This test reproduce the final insertion of the tie rods inside the outer vacuum tank.

  10. Tesla Coil Theoretical Model and its Experimental Verification

    OpenAIRE

    Voitkans Janis; Voitkans Arnis

    2015-01-01

    In this paper a theoretical model of Tesla coil operation is proposed. Tesla coil is described as a long line with distributed parameters in a single-wire form, where the line voltage is measured across electrically neutral space. By applying the principle of equivalence of single-wire and two-wire schemes an equivalent two-wire scheme can be found for a single-wire scheme and the already known long line theory can be applied to the Tesla coil. A new method of multiple reflections is develope...

  11. ALEPH Coil

    CERN Multimedia

    ALEPH was one of the four experiments installed at the LEP particle accelerator from 1989 - 2000. The detector was used by a collaboration of hundreds of physicists, mostly from Europe but also from China and the USA. The ALEPH superconducting magnet coils provide a very uniform magnetic field of 1.5 Tesla. The current in the coil is about 5000 A and the stored energy is 136 MJ. The coils are cooled by liquid Helium. Two correction coils serve to improve the uniformity of the field. This piece is connected to OBJ-DE-054.

  12. α-Helical coiled-coil peptide materials for biomedical applications.

    Science.gov (United States)

    Wu, Yaoying; Collier, Joel H

    2017-03-01

    Self-assembling coiled coils, which occur commonly in native proteins, have received significant interest for the design of new biomaterials-based medical therapies. Considerable effort over recent years has led to a detailed understanding of the self-assembly process of coiled coils, and a diverse collection of strategies have been developed for designing functional materials using this motif. The ability to engineer the interface between coiled coils allows one to achieve variously connected components, leading to precisely defined structures such as nanofibers, nanotubes, nanoparticles, networks, gels, and combinations of these. Currently these materials are being developed for a range of biotechnological and medical applications, including drug delivery systems for controlled release, targeted nanomaterials, 'drug-free' therapeutics, vaccine delivery systems, and others. WIREs Nanomed Nanobiotechnol 2017, 9:e1424. doi: 10.1002/wnan.1424 For further resources related to this article, please visit the WIREs website. © 2016 Wiley Periodicals, Inc.

  13. Optimization of a conduction-cooled LTS pulse coil

    Energy Technology Data Exchange (ETDEWEB)

    Kawagoe, A. [Kagoshima University, Kohrimoto 1-21-40, Kagoshima-shi, Kagoshima 890-0065 (Japan)]. E-mail: kawagoe@eee.kagoshima-u.ac.jp; Yamamuro, H. [Kagoshima University, Kohrimoto 1-21-40, Kagoshima-shi, Kagoshima 890-0065 (Japan); Sumiyoshi, F. [Kagoshima University, Kohrimoto 1-21-40, Kagoshima-shi, Kagoshima 890-0065 (Japan); Mito, T. [National Institute for Fusion Science, Toki, Gifu 509-5292 (Japan); Chikaraishi, H. [National Institute for Fusion Science, Toki, Gifu 509-5292 (Japan); Hemmi, T. [National Institute for Fusion Science, Toki, Gifu 509-5292 (Japan); Baba, T. [National Institute for Fusion Science, Toki, Gifu 509-5292 (Japan); Yokota, M. [National Institute for Fusion Science, Toki, Gifu 509-5292 (Japan); Morita, Y. [National Institute for Fusion Science, Toki, Gifu 509-5292 (Japan); Ogawa, H. [National Institute for Fusion Science, Toki, Gifu 509-5292 (Japan); Abe, R. [Shibuya Kogyo Co., Ltd., Kanazawa, Ishikawa 920-0054 (Japan); Okumura, K. [Technova Inc., Chiyoda-ku, Tokyo 100-0011 (Japan); Iwakuma, M. [Kyushu University, Higashi-ku, Fukuoka 812-8581 (Japan)

    2006-11-15

    The output limit of the available power of a prototype conduction-cooled low temperature superconducting (LTS) pulse coil is clarified for the optimization of the coil. The winding conductor of this coil is a NbTi/Cu Rutherford cable, which is extruded with aluminum. Dyneema[reg] fiber reinforced plastics (DFRP) and Litz wires are used as the spacers of this coil. A prototype coil with a stored energy of 100 kJ was successfully fabricated and tested, and the coil performed excellently. In this paper, the stability margin of this coil is clarified by thermal analysis, using a two-dimensional finite element method, taking into account the effects of both types of spacers, DFRP and Litz wires. Additionally, the maximum output power of the coil is estimated at about three times the rated output.

  14. Electrical wire as a foreign body in a male urethra: a case report

    Directory of Open Access Journals (Sweden)

    Stravodimos Konstantinos G

    2009-02-01

    Full Text Available Abstract Introduction Self-inflicted foreign bodies in the male urethra and urinary bladder are an emergency that urologists may rarely have to face. A case of an electrical wire inserted in the male urethra and coiled in the bladder is presented. Case presentation A 53-year-old male presented with the inability to void and bloody urethral discharge after having introduced an electrical wire in his urethra for masturbation 3 hours earlier. He had made several unsuccessful attempts to remove it. Conclusion The variety of these objects may be impressive and removal of the foreign body may be quite challenging requiring imagination and high-level surgical skills., In this case an electrical wire was used and the diagnostic as well as the therapeutic steps for its removal are presented.

  15. Magnesium Diboride Superconducting Coils for Electric Propulsion Systems for Large Aircraft Project

    Data.gov (United States)

    National Aeronautics and Space Administration — The recent development of magnesium diboride superconducting wires makes possible the potential to have much lighter weight superconducting coils for heavy aircraft...

  16. Magnetic wires in MEMS and bio-medical applications

    Energy Technology Data Exchange (ETDEWEB)

    Barbic, Mladen E-mail: mladen@caltech.edu

    2002-08-01

    Magnetic wires of appropriate design have special features making them useful to micro-electromechanical systems and bio-medical applications. Several applications that exploit the properties of magnetic wires are reviewed including: (a) a magnetic micro-manipulation technique that utilizes integrated micro-coils and magnetic micro-wires for localized positioning of micron-sized magnetic objects, (b) integrated micro-coil/micro-wire system operating as a micro-fluidic micro-motor, (c) mechanical tweezers using magneto-static interaction between two magnetic micro-wires, and (d) ultra-high gradient magnetic separation system based on porous membranes partially filled with magnetic wires.

  17. Treatment of aneurysms with wires and electricity: a historical overview.

    Science.gov (United States)

    Siddique, Khawar; Alvernia, Jorge; Fraser, Kenneth; Lanzino, Giuseppe

    2003-12-01

    Endovascular treatment of aneurysms has only recently become an accepted therapeutic modality. Nonetheless, treatment of aneurysms with the aid of various foreign bodies such as needle and wire insertion with or without electrical current has been reported since the first half of the 19th century. In 1832 Phillips induced clot formation in the femoral and carotid arteries of dogs by leaving needles in the arteries for variable lengths of time. Simultaneously, in France, Velpeau had proposed using "l'acupuncture des arteres dans le traitement des anevrismes." Later, Phillips and Pelrequin connected the offending needles to a source of electrical current in an attempt to increase thrombus formation and aneurysm occlusion. Subsequently, Moore introduced the concept of packing the aneurysm with wire inserted through a needle transfixed to the vessel wall. To this method, Corradi added electrical current. Widely known as the Moore-Corradi technique, it was used in ensuing years with variable success. The early phase of endovascular aneurysm treatment culminated when Blakemore and Moore treated a case of symptomatic cavernous sinus aneurysm by passing wire through the patient's orbit. These pioneering cases combined with technological advances in the diagnosis of intracranial aneurysms paved the way for further refinements in coil embolization of aneurysms.

  18. Tesla Coil Theoretical Model and its Experimental Verification

    Directory of Open Access Journals (Sweden)

    Voitkans Janis

    2014-12-01

    Full Text Available In this paper a theoretical model of Tesla coil operation is proposed. Tesla coil is described as a long line with distributed parameters in a single-wire form, where the line voltage is measured across electrically neutral space. By applying the principle of equivalence of single-wire and two-wire schemes an equivalent two-wire scheme can be found for a single-wire scheme and the already known long line theory can be applied to the Tesla coil. A new method of multiple reflections is developed to characterize a signal in a long line. Formulas for calculation of voltage in Tesla coil by coordinate and calculation of resonance frequencies are proposed. The theoretical calculations are verified experimentally. Resonance frequencies of Tesla coil are measured and voltage standing wave characteristics are obtained for different output capacities in the single-wire mode. Wave resistance and phase coefficient of Tesla coil is obtained. Experimental measurements show good compliance with the proposed theory. The formulas obtained in this paper are also usable for a regular two-wire long line with distributed parameters.

  19. Anchor coil technique for arteriovenous fistula embolization. A technical note.

    Science.gov (United States)

    Kanemaru, Kazuya; Ezura, Masayuki; Nishiyama, Yoshihisa; Yagi, Takashi; Yoshioka, Hideyuki; Fukumoto, Yuichiro; Horikoshi, Toru; Kinouchi, Hiroyuki

    2014-01-01

    We describe a case of arteriovenous fistula (AVF) successfully treated by coil embolization with an anchor coil inserted in the varix to facilitate dense packing at the shunting site. AVF of the left anterior choroidal artery (AChoA) draining into the ipsilateral basal vein of Rosenthal was incidentally found in a newborn female. A single detachable coil was inserted as an anchor into the varix adjacent to the shunt, and the microcatheter was pulled back to the shunting point. Three more detachable coils were delivered at the shunting point without migration under the support of the anchor coil, and the AVF was successfully obliterated with preservation of AChoA blood flow. The anchor coil technique can reduce the risk of coil migration and the number of coils required.

  20. Wireless power transmission applied the mutual coupling between coils

    Science.gov (United States)

    Furuta, Kenta; Baba, Ryouichi; Shun, Endo; Nunokawa, Kazuki; Takahashi, Wataru; Maruyama, Tamami

    2017-07-01

    Recently, the studies of wireless power transfer (WPT) to electric vehicles in motion on the snow-piled road have been reported. In WPT by magnetic field resonance method, transmission coefficient S21, which is one of the scattering parameters, from transmission coil to received coil are degraded because of misalignment of transmitting and receiving coil, the distance between these coils, and the effects of the ice and snow. This paper adopts parasitic coil as a solution to improve the reception power in which the parasitic coil is inserted between transmitting and receiving coils. Analysis and experimental results show that parasitic coil could improve the value of S21 by 15 dB using mutual coupling. LED could be light by this solution when the distance between transmitting and receiving coils are 150 mm.

  1. Rectangle Surface Coil Array in a Grid Arrangement for Resonance Imaging

    Science.gov (United States)

    2016-02-13

    magnet wires with insulating coating for rectangular surface coils. The wires are formed into four one turn 145mm x 32mm rectangular coils...switchable array, RF magnetic field, NQR, MRI, NMR, tuning, decoupling I. INTRODUCTION ESONANCE imaging can be accomplished using Nuclear Magnetic ...grid array. This achieves the switchable array configuration. Later, investigations will have circuit controlled multiplexer for switching to

  2. Coiled-Coil Design: Updated and Upgraded.

    Science.gov (United States)

    Woolfson, Derek N

    2017-01-01

    α-Helical coiled coils are ubiquitous protein-folding and protein-interaction domains in which two or more α-helical chains come together to form bundles. Through a combination of bioinformatics analysis of many thousands of natural coiled-coil sequences and structures, plus empirical protein engineering and design studies, there is now a deep understanding of the sequence-to-structure relationships for this class of protein architecture. This has led to considerable success in rational design and what might be termed in biro de novo design of simple coiled coils, which include homo- and hetero-meric parallel dimers, trimers and tetramers. In turn, these provide a toolkit for directing the assembly of both natural proteins and more complex designs in protein engineering, materials science and synthetic biology. Moving on, the increased and improved use of computational design is allowing access to coiled-coil structures that are rare or even not observed in nature, for example α-helical barrels, which comprise five or more α-helices and have central channels into which different functions may be ported. This chapter reviews all of these advances, outlining improvements in our knowledge of the fundamentals of coiled-coil folding and assembly, and highlighting new coiled coil-based materials and applications that this new understanding is opening up. Despite considerable progress, however, challenges remain in coiled-coil design, and the next decade promises to be as productive and exciting as the last.

  3. Simulation of defects on contactor coil

    Science.gov (United States)

    Erdei, Z.; Horgos, M.; Zetea, O.

    2017-05-01

    By definition, a coil is an electrical passive device, which have two terminals, use in electrical circuits to keep the power in magnetic field or to detect the magnetic fields. In winding process, is possible to appear different defects, or issues which can cause in time problems in functionality of products. In this paper, we will analyze two types of defectives what were observed in winding process. In first type of defect, some wires of beginning of winding remain out of normal winding, and the wires are visible from outside, and in second type of defect, same beginning of winding remain inside of coil, under the normal winding, not in correct position. For simulation, we will used an assembly compose by anchor, electromagnet and coil. Those are parts of contactor.

  4. Wire chamber

    CERN Multimedia

    1967-01-01

    Magnetoscriptive readout wire chamber.Multi-wire detectors contain layers of positively and negatively charged wires enclosed in a chamber full of gas. A charged particle passing through the chamber knocks negatively charged electrons out of atoms in the gas, leaving behind positive ions. The electrons are pulled towards the positively charged wires. They collide with other atoms on the way, producing an avalanche of electrons and ions. The movement of these electrons and ions induces an electric pulse in the wires which is collected by fast electronics. The size of the pulse is proportional to the energy loss of the original particle.

  5. Wire Chamber

    CERN Multimedia

    Magnetoscriptive readout wire chamber. Multi-wire detectors contain layers of positively and negatively charged wires enclosed in a chamber full of gas. A charged particle passing through the chamber knocks negatively charged electrons out of atoms in the gas, leaving behind positive ions. The electrons are pulled towards the positively charged wires. They collide with other atoms on the way, producing an avalanche of electrons and ions. The movement of these electrons and ions induces an electric pulse in the wires which is collected by fast electronics. The size of the pulse is proportional to the energy loss of the original particle.

  6. wire chamber

    CERN Multimedia

    Proportional multi-wire chamber. Multi-wire detectors contain layers of positively and negatively charged wires enclosed in a chamber full of gas. A charged particle passing through the chamber knocks negatively charged electrons out of atoms in the gas, leaving behind positive ions. The electrons are pulled towards the positively charged wires. They collide with other atoms on the way, producing an avalanche of electrons and ions. The movement of these electrons and ions induces an electric pulse in the wires which is collected by fast electronics. The size of the pulse is proportional to the energy loss of the original particle. Proportional wire chambers allow a much quicker reading than the optical or magnetoscriptive readout wire chambers.

  7. Spaced-based search coil magnetometers

    Science.gov (United States)

    Hospodarsky, George B.

    2016-12-01

    Search coil magnetometers are one of the primary tools used to study the magnetic component of low-frequency electromagnetic waves in space. Their relatively small size, mass, and power consumption, coupled with a good frequency range and sensitivity, make them ideal for spaceflight applications. The basic design of a search coil magnetometer consists of many thousands of turns of wire wound on a high permeability core. When a time-varying magnetic field passes through the coil, a time-varying voltage is induced due to Faraday's law of magnetic induction. The output of the coil is usually attached to a preamplifier, which amplifies the induced voltage and conditions the signal for transmission to the main electronics (usually a low-frequency radio receiver). Search coil magnetometers are usually used in conjunction with electric field antenna to measure electromagnetic plasma waves in the frequency range of a few hertz to a few tens of kilohertzs. Search coil magnetometers are used to determine the properties of waves, such as comparing the relative electric and magnetic field amplitudes of the waves, or to investigate wave propagation parameters, such as Poynting flux and wave normal vectors. On a spinning spacecraft, they are also sometimes used to determine the background magnetic field. This paper presents some of the basic design criteria of search coil magnetometers and discusses design characteristics of sensors flown on a number of spacecraft.

  8. Programming protein self assembly with coiled coils

    Energy Technology Data Exchange (ETDEWEB)

    Dietz, Hendrik; Bornschloegl, Thomas; Heym, Roland; Koenig, Frauke; Rief, Matthias [Physik Department E22, Technische Universitaet Muenchen, James-Franck-Strasse 1, 85748 Garching (Germany)

    2007-11-15

    The controlled assembly of protein domains into supramolecular structures will be an important prerequisite for the use of functional proteins in future nanotechnology applications. Coiled coils are multimerization motifs whose dimerization properties can be programmed by amino acid sequence. Here, we report programmed supramolecular self-assembly of protein molecules using coiled coils and directly demonstrate its potential on the single molecule level by AFM force spectroscopy. We flanked two different model proteins, Ig27 from human cardiac titin and green fluorescent protein (GFP), by coiled coil binding partners and studied the capability of these elementary building blocks to self-assemble into linear chains. Simple sterical constraints are shown to control the assembly process, providing evidence that many proteins can be assembled with this method. An application for this technique is the design of polyproteins for single molecule force spectroscopy with an integrated force-calibration standard.

  9. wire chamber

    CERN Multimedia

    Was used in ISR (Intersecting Storage Ring) split field magnet experiment. Multi-wire detectors contain layers of positively and negatively charged wires enclosed in a chamber full of gas. A charged particle passing through the chamber knocks negatively charged electrons out of atoms in the gas, leaving behind positive ions. The electrons are pulled towards the positively charged wires. They collide with other atoms on the way, producing an avalanche of electrons and ions. The movement of these electrons and ions induces an electric pulse in the wires which is collected by fast electronics. The size of the pulse is proportional to the energy loss of the original particle.

  10. wire chamber

    CERN Multimedia

    1985-01-01

    Multi-wire detectors contain layers of positively and negatively charged wires enclosed in a chamber full of gas. A charged particle passing through the chamber knocks negatively charged electrons out of atoms in the gas, leaving behind positive ions. The electrons are pulled towards the positively charged wires. They collide with other atoms on the way, producing an avalanche of electrons and ions. The movement of these electrons and ions induces an electric pulse in the wires which is collected by fast electronics. The size of the pulse is proportional to the energy loss of the original particle.

  11. wire chamber

    CERN Multimedia

    Multi-wire detectors contain layers of positively and negatively charged wires enclosed in a chamber full of gas. A charged particle passing through the chamber knocks negatively charged electrons out of atoms in the gas, leaving behind positive ions. The electrons are pulled towards the positively charged wires. They collide with other atoms on the way, producing an avalanche of electrons and ions. The movement of these electrons and ions induces an electric pulse in the wires which is collected by fast electronics. The size of the pulse is proportional to the energy loss of the original particle.

  12. Wire chamber

    CERN Multimedia

    Multi-wire detectors contain layers of positively and negatively charged wires enclosed in a chamber full of gas. A charged particle passing through the chamber knocks negatively charged electrons out of atoms in the gas, leaving behind positive ions. The electrons are pulled towards the positively charged wires. They collide with other atoms on the way, producing an avalanche of electrons and ions. The movement of these electrons and ions induces an electric pulse in the wires which is collected by fast electronics. The size of the pulse is proportional to the energy loss of the original particle.

  13. Slice of LHC dipole wiring

    CERN Multimedia

    Dipole model slice made in 1994 by Ansaldo. The high magnetic fields needed for guiding particles around the Large Hadron Collider (LHC) ring are created by passing 12’500 amps of current through coils of superconducting wiring. At very low temperatures, superconductors have no electrical resistance and therefore no power loss. The LHC is the largest superconducting installation ever built. The magnetic field must also be extremely uniform. This means the current flowing in the coils has to be very precisely controlled. Indeed, nowhere before has such precision been achieved at such high currents. 50’000 tonnes of steel sheets are used to make the magnet yokes that keep the wiring firmly in place. The yokes constitute approximately 80% of the accelerator's weight and, placed side by side, stretch over 20 km!

  14. Caída de presión de un flujo turbulento en un espacio anular con hélices insertadas//The pressure drop of turbulent flow in an annular space with wire coil inserts

    OpenAIRE

    Josué Imbert González; Octavio García Valladares; Reinaldo Guillen Gordín

    2015-01-01

    El trabajo presentado evaluó el comportamiento experimental de la caída de presión en un espacio anular con alambres enrollados insertados para números de Reynolds entre 1500 y 5000. La zona de prueba se seleccionó alejada de la influencia de los efectos de entrada. Anteriormente se realizaron pruebas de visualización del flujo para verificar la presencia de un flujo turbulento en esta gama del número de Reynolds. A partir de los datos experimentales se obtuvieron ecuaciones de correlación de...

  15. Fabrication of pulsed magnets with a linear-type coil-winding machine

    Science.gov (United States)

    Suzuki, O.; Sakamoto, K.; Imanaka, Y.; Kido, G.

    2001-01-01

    We developed a linear-type coil-winding machine for the fabrication of pulsed magnets. This machine is compact and makes the process of winding a wire easier. The wire is led to a coil shaft through a pair of timing-belts. Kapton tape and Zylon fiber are wrapped on the wire by interlocking with the drive part of the timing-belts. A test magnet fabricated with the linear-type coil-winding machine generates magnetic fields above 63 T.

  16. A Magnetic Sensor with Amorphous Wire

    Directory of Open Access Journals (Sweden)

    Dongfeng He

    2014-06-01

    Full Text Available Using a FeCoSiB amorphous wire and a coil wrapped around it, we have developed a sensitive magnetic sensor. When a 5 mm long amorphous wire with the diameter of 0.1 mm was used, the magnetic field noise spectrum of the sensor was about 30 pT/ÖHz above 30 Hz. To show the sensitivity and the spatial resolution, the magnetic field of a thousand Japanese yen was scanned with the magnetic sensor.

  17. Immune responses to coiled coil supramolecular biomaterials.

    Science.gov (United States)

    Rudra, Jai S; Tripathi, Pulak K; Hildeman, David A; Jung, Jangwook P; Collier, Joel H

    2010-11-01

    Self-assembly has been increasingly utilized in recent years to create peptide-based biomaterials for 3D cell culture, tissue engineering, and regenerative medicine, but the molecular determinants of these materials' immunogenicity have remained largely unexplored. In this study, a set of molecules that self-assembled through coiled coil oligomerization was designed and synthesized, and immune responses against them were investigated in mice. Experimental groups spanned a range of oligomerization behaviors and included a peptide from the coiled coil region of mouse fibrin that did not form supramolecular structures, an engineered version of this peptide that formed coiled coil bundles, and a peptide-PEG-peptide triblock bioconjugate that formed coiled coil multimers and supramolecular aggregates. In mice, the native peptide and engineered peptide did not produce any detectable antibody response, and none of the materials elicited detectable peptide-specific T cell responses, as evidenced by the absence of IL-2 and interferon-gamma in cultures of peptide-challenged splenocytes or draining lymph node cells. However, specific antibody responses were elevated in mice injected with the multimerizing peptide-PEG-peptide. Minimal changes in secondary structure were observed between the engineered peptide and the triblock peptide-PEG-peptide, making it possible that the triblock's multimerization was responsible for this antibody response. Copyright (c) 2010 Elsevier Ltd. All rights reserved.

  18. Modelling of lossy coils using fractional derivatives

    Science.gov (United States)

    Schäfer, Ingo; Krüger, Klaus

    2008-02-01

    Coils exposed to eddy current and hysteresis losses are conventionally described by an inductance with equivalent core-loss resistance connected in parallel. The value of the equivalent core-loss resistance depends on the working frequency and the external wiring. Thus the model is less than satisfactory. The authors propose to describe loss inductance using fractional derivatives containing both a loss term and a storage term. After introducing the theory of fractional derivatives, the operating mode of the fractional coil model is explained by the example of an RLC oscillating circuit. Subsequent measurements of a series resonant circuit with a lossy coil impressively confirm the theoretical model with regard to both the frequency and time domains.

  19. HTS Wire Development Workshop: Proceedings

    Energy Technology Data Exchange (ETDEWEB)

    1994-07-01

    The 1994 High-Temperature Superconducting Wire Development Workshop was held on February 16--17 at the St. Petersburg Hilton and Towers in St. Petersburg, Florida. The meeting was hosted by Florida Power Corporation and sponsored by the US Department of Energy`s Superconductivity Program for Electric Power Systems. The meeting focused on recent high-temperature superconducting wire development activities in the Department of Energy`s Superconductivity Systems program. The meeting opened with a general discussion on the needs and benefits of superconductivity from a utility perspective, the US global competitiveness position, and an outlook on the overall prospects of wire development. The meeting then focused on four important technology areas: Wire characterization: issues and needs; technology for overcoming barriers: weak links and flux pinning; manufacturing issues for long wire lengths; and physical properties of HTS coils. Following in-depth presentations, working groups were formed in each technology area to discuss the most important current research and development issues. The working groups identified research areas that have the potential for greatly enhancing the wire development effort. These areas are discussed in the summary reports from each of the working groups. This document is a compilation of the workshop proceedings including all general session presentations and summary reports from the working groups.

  20. Dual coil ignition system

    Science.gov (United States)

    Huberts, Garlan J.; Qu, Qiuping; Czekala, Michael Damian

    2017-03-28

    A dual coil ignition system is provided. The dual coil ignition system includes a first inductive ignition coil including a first primary winding and a first secondary winding, and a second inductive ignition coil including a second primary winding and a second secondary winding, the second secondary winding connected in series to the first secondary winding. The dual coil ignition system further includes a diode network including a first diode and a second diode connected between the first secondary winding and the second secondary winding.

  1. High-Field Quench Behavior and Protection of $Bi_2 Sr_2 Ca Cu_2 O_x$ Coils: Minimum and Maximum Quench Detection Voltages

    Energy Technology Data Exchange (ETDEWEB)

    Shen, Tengming [Fermilab; Ye, Liyang [NCSU, Raleigh; Turrioni, Daniele [Fermilab; Li, Pei [Fermilab

    2015-01-01

    Small insert coils have been built using a multifilamentary Bi2Sr2CaCu2Ox round wire, and characterized in background fields to explore the quench behaviors and limits of Bi2Sr2CaCu2Ox superconducting magnets, with an emphasis on assessing the impact of slow normal zone propagation on quench detection. Using heaters of various lengths to initiate a small normal zone, a coil was quenched safely more than 70 times without degradation, with the maximum coil temperature reaching 280 K. Coils withstood a resistive voltage of tens of mV for seconds without quenching, showing the high stability of these coils and suggesting that the quench detection voltage shall be greater than 50 mV to not to falsely trigger protection. The hot spot temperature for the resistive voltage of the normal zone to reach 100 mV increases from ~40 K to ~80 K with increasing the operating wire current density Jo from 89 A/mm2 to 354 A/mm2 whereas for the voltage to reach 1 V, it increases from ~60 K to ~140 K, showing the increasing negative impact of slow normal zone propagation on quench detection with increasing Jo and the need to limit the quench detection voltage to < 1 V. These measurements, coupled with an analytical quench model, were used to access the impact of the maximum allowable voltage and temperature upon quench detection on the quench protection, assuming to limit the hot spot temperature to <300 K.

  2. Homogenous BSCCO-2212 Round Wires for Very High Field Magnets

    Energy Technology Data Exchange (ETDEWEB)

    Dr. Scott Campbell

    2012-06-30

    the very significant advantage of an extremely high H{sub c2}. For this reason, Bi{sub 2}Sr{sub 2}CaCu{sub 2}O{sub y} (Bi-2212, or 2212) in the form of a multifilamentary Ag alloy matrix composite is beginning to attract the interest of the magnet community for future extremely high-field magnets or magnet-insert coils for 4.2K operation. Fig. 1 shows an example of excellent JE (engineering current density) in Bi-2212 round wire at fields up to 45 T, demonstrating the potential for high field applications of this material. For comparison, the Nb{sub 3}Sn wires used in magnets in the 16-18 T range typically perform with J{sub E} in the range 200-500 A/mm{sup 2}; the Bi-2212 wire retains this level of performance to fields at least as high as 45 T, and probably significantly higher. Bi-2212 conductors have in fact been used to generate a 25 T field in a superconducting insert magnet. These two factors- the very high field critical current performance of Bi-2212, and the already demonstrated capability of this material for high field magnets up to 25 T, strongly suggest this material as a leading contender for the next generation high field superconducting (HFS) wire. This potential was recognized by the US Academy of Science's Committee on Opportunities in High Magnetic Field Science. Their report of the same name specifically calls out the high field potential for this material, and suggests that 30 T magnets appear feasible based on the performance of 2212. There are several requirements for HFS conductors. The most obvious is J{sub E} (B, T), the engineering current density at the field and temperature of operation. As shown in Fig. 1, Bi-2212 excels in this regard. Stability requirements for magnets dictate that the effective filament diameter should be less than 30 micrometers, something that Bi-2212 multifilamentary wire can uniquely satisfy among the HFS superconducting wire technologies. Additional requirements include mechanical properties that prevent

  3. Detailed 3D models of the induced electric field of transcranial magnetic stimulation coils

    Energy Technology Data Exchange (ETDEWEB)

    Salinas, F S; Lancaster, J L; Fox, P T [Research Imaging Center, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229 (United States)

    2007-05-21

    Previous models neglected contributions from current elements spanning the full geometric extent of wires in transcranial magnetic stimulation (TMS) coils. A detailed account of TMS coil wiring geometry is shown to provide significant improvements in the accuracy of electric field (E-field) models. Modeling E-field dependence based on the TMS coil's wire width, height, shape and number of turns clearly improved the fit of calculated-to-measured E-fields near the coil body. Detailed E-field models were accurate up to the surface of the coil body (within 0.5% of measured) where simple models were often inadequate (up to 32% different from measured)

  4. Biomaterials Made from Coiled-Coil Peptides.

    Science.gov (United States)

    Conticello, Vincent; Hughes, Spencer; Modlin, Charles

    The development of biomaterials designed for specific applications is an important objective in personalized medicine. While the breadth and prominence of biomaterials have increased exponentially over the past decades, critical challenges remain to be addressed, particularly in the development of biomaterials that exhibit highly specific functions. These functional properties are often encoded within the molecular structure of the component molecules. Proteins, as a consequence of their structural specificity, represent useful substrates for the construction of functional biomaterials through rational design. This chapter provides an in-depth survey of biomaterials constructed from coiled-coils, one of the best-understood protein structural motifs. We discuss the utility of this structurally diverse and functionally tunable class of proteins for the creation of novel biomaterials. This discussion illustrates the progress that has been made in the development of coiled-coil biomaterials by showcasing studies that bridge the gap between the academic science and potential technological impact.

  5. Misalignment tolerable coil structure for biomedical applications with wireless power transfer.

    Science.gov (United States)

    Chow, Jeff P W; Chen, Nan; Chung, Henry S H; Chan, Leanne L H

    2013-01-01

    Coil-misalignment is one of the major hurdles for inductively coupled wireless power transfer in applications like retinal prosthesis. Weak magnetic flux linkage due to coil misalignments would significantly impair the power efficiency. A novel receiver configuration with high misalignment tolerance is presented in this paper. The proposed receiver is composed of two receiver coils placed orthogonally, so as to reduce the variation of mutual inductance between transmitting and receiving coils under misalignment conditions. Three different receiver coil structures are analyzed and compared using the same length of wire. Theoretical predictions have been confirmed with measurement results.

  6. AC losses of oxide superconducting coils operated in liquid nitrogen; Ekitai chisso reikyaku sankabutsu chodendo koiru no koryu sonshitsu

    Energy Technology Data Exchange (ETDEWEB)

    Fukushige, K.; Hayashida, T.; Sumiyoshi, F.; Kawabata, S. [Kagoshima Univ., Kagoshima (Japan); Hayashi, H. [Kyushu Electric Power Co., Inc., Fukuoka (Japan)

    1999-06-07

    As a basic research with the aim of practical application of the liquid nitrogen cooling oxide superconductivity coil, the double pancake-shape coil was produced experimentally using Bi system polycore tape wire rod, and the characteristic evaluation was carried out. Especially, it tried to examine the measured value of ac loss in the coil energization using analytical result of magnetic field distribution which is added to coil winding and magnetization loss data of the short length sample. (NEDO)

  7. New directions in the design of MRI gradient coils

    Science.gov (United States)

    Baig, Tanvir Noor

    In this dissertation new designs for gradient coils are presented. The principal work is on better shielding for fringe field reduction. Fringe fields from gradient coils produce eddy currents in surrounding metal structures. Such eddy currents can degrade image quality and lead to acoustic noise. The acoustic effects are magnified for high-field Magnetic Resonance Imaging (MRI) scanners because of increased Lorentz forces. Conventional actively shielded gradient assemblies consist of primary and secondary coils in the shape of cylindrical shells surrounding the imaging volume. One of the principal regions of field leakage is at the ends of the gradient structure, and these fields are responsible for substantial eddy current generation. Our new shielded gradient coil designs that feature the inclusion of an endcap have significantly reduced fringe field at the cryostat inner bore. We discuss the degree to which the suppression of peak fringe fields corresponds to a reduction in the acoustic noise generated near the end of the warm bore. Energy efficient capped actively shielded elliptical gradient coils are also designed. In comparison with traditional uncapped elliptical designs the newly proposed design substantially reduces the fringe field at the inner cryostat bore. And compared to a cylindrical design (with a diameter matched to the elliptical semi-major axis), a good reduction in magnetic energy is observed. In addition, a design for a very short, symmetrical, and winged X-gradient insertable head coil is presented. With a smaller radius, an insertable head gradient coil has the advantage of less stored magnetic energy. The corresponding smaller inductance leads to higher slew rates. Lower torque from Lorentz forces is another advantage for these coils. When designing an insertable head coil one must remember the geometry is impacted by the shoulders. In consequence, asymmetric unshielded and shielded designs have been developed. Gradient designs with a

  8. Insertion devices

    CERN Document Server

    Bahrdt, J

    2006-01-01

    The interaction of an insertion device with the electron beam in a storage ring is discussed. The radiation property including brightness, ux and polarization of an ideal and real planar and helical / elliptical device is described. The magnet design of planar, helical, quasiperiodic devices and of devices with a reduced on axis power density are resumed.

  9. Calorimeter insertion

    CERN Multimedia

    2006-01-01

    Calorimeter insertion between toroids in the ATLAS experiment detector Calorimeters are surrounding the inner detector. Calorimeters will absorb and measure the energies of the most charged and neutral particles after the collisions. The saved energy in the calorimeter is detected and converted to signals that are taken out with data taking electronics.

  10. Flux Redux: The Spinning Coil Comes around Again

    Science.gov (United States)

    Lund, Daniel; Dietz, Eric; Zou, Xueli; Ard, Christopher; Lee, Jaydie; Kaneshiro, Chris; Blanton, Robert; Sun, Steven

    2017-01-01

    An essential laboratory exercise for our lower-division electromagnetism course involves the measurement of Earth's local magnetic field from the emf induced in a rotating coil of wire. Although many methods exist for the measurement of Earth's field, this one gives our students some practical experience with Faraday's law. The apparatus we had…

  11. Update on High-Temperature Coils for Electromagnets

    Science.gov (United States)

    Kascak, Albert F.; Montague, Gerald T.; Palazzolo, Alan; Preuss, Jason; Carter, Bart; Tucker, Randall; Hunt, Andrew

    2005-01-01

    A report revisits the subject matter of "High-Temperature Coils for Electromagnets" (LEW-17164), NASA Tech Briefs, Vol. 26, No. 8, (August 2002) page 38. To recapitulate: Wires have been developed for use in electromagnets that operate at high temperatures. The starting material for a wire of this type can be either a nickel-clad, ceramic-insulated copper wire or a bare silver wire. The wire is covered by electrical-insulation material that is intended to withstand operating temperatures in the range from 800 to 1,300 F (.430 to .700 C): The starting wire is either primarily wrapped with S-glass as an insulating material or else covered with another insulating material wrapped in S-glass prior to the winding process. A ceramic binding agent is applied as a slurry during the winding process to provide further insulating capability. The turns are pre-bent during winding to prevent damage to the insulation. The coil is then heated to convert the binder into ceramic. The instant report mostly reiterates the prior information and presents some additional information on the application of the ceramic binding agent and the incorporation of high-temperature wire into the windings.

  12. Liquid rope coiling

    NARCIS (Netherlands)

    Ribe, N.M.; Habibi, M.; Bonn, D.

    2012-01-01

    A thin stream or rope of viscous fluid falling from a sufficient height onto a surface forms a steadily rotating helical coil. Tabletop laboratory experiments in combination with a numerical model for slender liquid ropes reveal that finite-amplitude coiling can occur in four distinct regimes

  13. An Air Bearing Rotating Coil Magnetic Measurement System

    CERN Document Server

    Gottschalk, Stephen C; Taylor, David J; Thayer, William

    2005-01-01

    This paper describes a rotating coil magnetic measurement system supported on air bearings. The design is optimized for measurements of 0.1micron magnetic centerline changes on long, small aperture quadrupoles. Graphite impregnated epoxy resin is used for the coil holder and coil winding forms. Coil holder diameter is 11 mm with a length between supports of 750mm. A pair of coils is used to permit quadrupole bucking during centerline measurements. Coil length is 616mm, inner radius 1.82mm, outer radius 4.74mm. The key features of the mechanical system are simplicity; air bearings for accurate, repeatable measurements without needing warm up time and a vibration isolated stand that uses a steel-topped Newport optical table with air suspension. Coil rotation is achieved by a low noise servo motor controlled by a standalone Ethernet servo board running custom servo software. Coil calibration procedures that correct wire placement errors, tests for mechanical resonances, and other system checks will also be discu...

  14. Synthesis, characterisation and applications of coiled carbon nanotubes.

    Science.gov (United States)

    Hanus, Monica J; Harris, Andrew T

    2010-04-01

    Coiled carbon nanotubes are helical carbon structures formed when heptagonal and pentagonal rings are inserted into the hexagonal backbone of a 'straight' nanotube. Coiled carbon nanotubes have been reported with both regular and irregular helical structures. In this work the structure, growth mechanism(s), synthesis, properties and potential applications of coiled carbon nanotubes are reviewed. Published data suggests that coiled carbon nanotube synthesis occurs due to nonuniform extrusion of carbon from a catalyst surface. To date, coiled carbon nanotubes have been synthesised using catalyst modification techniques including: (i) the addition of S or P containing compounds during synthesis; (ii) the use of binary or ternary metal catalysts; (iii) the use of microwaves to create a local temperature gradient around individual catalyst particles and; (iv) the use of pH control during catalyst preparation. In most instances coiled carbon nanotubes are produced as a by-product; high yield and/or large-scale synthesis of coiled carbon nanotubes remains problematic. The qualitative analysis of coiled carbon nanotubes is currently hindered by the absence of specific characterisation data in the literature, e.g., oxidation profiles measured by thermogravimetric analysis and Raman spectra of pure coiled carbon nanotube samples.

  15. Niobium Titanium and Copper wire samples

    CERN Document Server

    2009-01-01

    Two wire samples, both for carrying 13'000Amperes. I sample is copper. The other is the Niobium Titanium wiring used in the LHC magnets. The high magnetic fields needed for guiding particles around the Large Hadron Collider (LHC) ring are created by passing 12’500 amps of current through coils of superconducting wiring. At very low temperatures, superconductors have no electrical resistance and therefore no power loss. The LHC is the largest superconducting installation ever built. The magnetic field must also be extremely uniform. This means the current flowing in the coils has to be very precisely controlled. Indeed, nowhere before has such precision been achieved at such high currents. Magnet coils are made of copper-clad niobium–titanium cables — each wire in the cable consists of 9’000 niobium–titanium filaments ten times finer than a hair. The cables carry up to 12’500 amps and must withstand enormous electromagnetic forces. At full field, the force on one metre of magnet is comparable ...

  16. Separation of stimulating catheters for continuous peripheral regional anesthesia during their removal - two case reports and a critical appraisal of the use of steel-coil containing stimulating catheters.

    Science.gov (United States)

    Wiesmann, Thomas; Wallot, Pascal; Nentwig, Laura; Beermann, Alisha-Viktoria; Wulf, Hinnerk; Zoremba, Martin; Al-Dahna, Turfa; Eschbach, Daphne; Steinfeldt, Thorsten

    2015-01-01

    Stimulating catheters are widely used for continuous peripheral nerve block techniques in regional anesthesia. The incidence of reported complications is somewhat similar to that for non-stimulating catheters. However, as many stimulating catheters contain a coiled steel wire for optimal stimulation, they may cause specific complications. In this report, we present two cases of complicated removals of stimulating catheters. During both removals, a part of the metal wire was left "decoiled" next to the supraclavicular and interscalene plexus, respectively. The strategies used to determine steel wire localization and a description of the successful removal of these steel wires are included in this report. Catheter separation and problems with residual metal wire components of stimulating catheters seem to be a rare but specific problem during removal. Anesthesiologists should strictly avoid catheter shearing during insertion, adhere to the manufacturer's instructions, and take care during catheter removal. Manufacturers should focus on technical solutions to avoid rare but relevant complications such as catheter tip decoiling and separation of stimulating catheters during removal.

  17. EVALUATION OF INDUCTANCE WITH ELECTRICAL WIRES

    Directory of Open Access Journals (Sweden)

    V. Kudry

    2016-08-01

    Full Text Available In this paper proved the possibility of developing passive electronic inductive elements based replace metal wire that is wound inductor, the wire is made of electret. The relative permeability of the electret S  10 000, several orders of magnitude greater than the permeability of conventional insulation materials, i < 10, resulting current in the wire acquires properties bias current. The essence of innovation is to replace the source of of magnetic induction flow that pervades the core of the coil. According to the theory of electrodynamics, current bias, in contrast to conduction current, generated no movement of charge along the wire, but the change of the charge in the local volume.Equivalence bias current and conduction current is manifested in the possibility of forming a magnetic field. The flow through magnetic induction coil core regardless of the current it generates, creates voltage at its ends.The paper also shows the numeric characteristics that determine the effective frequency range, specified the reason why electric a wire with і < 10 can not generate magnetic flux through the core and serve as a passive reactive component.

  18. 78 FR 63450 - Carbon and Certain Alloy Steel Wire Rod From Brazil, Indonesia, Mexico, Moldova, Trinidad and...

    Science.gov (United States)

    2013-10-24

    ... International Trade Administration, Carbon and Certain Alloy Steel Wire Rod From Brazil, Indonesia, Mexico... on carbon and certain alloy steel wire rod (``wire rod'') from Brazil, Indonesia, Mexico, Moldova...-rolled products of carbon steel and alloy steel, in coils, of approximately round cross section, 5.00 mm...

  19. A periodic table of coiled-coil protein structures.

    Science.gov (United States)

    Moutevelis, Efrosini; Woolfson, Derek N

    2009-01-23

    Coiled coils are protein structure domains with two or more alpha-helices packed together via interlacing of side chains known as knob-into-hole packing. We analysed and classified a large set of coiled-coil structures using a combination of automated and manual methods. This led to a systematic classification that we termed a "periodic table of coiled coils," which we have made available at http://coiledcoils.chm.bris.ac.uk/ccplus/search/periodic_table. In this table, coiled-coil assemblies are arranged in columns with increasing numbers of alpha-helices and in rows of increased complexity. The table provides a framework for understanding possibilities in and limits on coiled-coil structures and a basis for future prediction, engineering and design studies.

  20. FINE-FILAMENT MAGNESIUM DIBORIDE SUPERCONDUCTOR WIRE FOR TURBOELECTRIC PROPULSION SYSTEMS Project

    Data.gov (United States)

    National Aeronautics and Space Administration — The availability of low AC loss magnesium diboride (MgB2) superconducting wires enables much lighter weight superconducting stator coils than with any other metal or...

  1. LHCb magnet coils arrive

    CERN Multimedia

    Maximilien Brice

    2003-01-01

    Each of the two coils for the LHCb magnet comprises 15 individual monolayer 'pancakes' of identical trapezoidal racetrack shape, and is bent at 45 degrees on the two transverse sides. Each pancake consists of eight turns of conductor, wound from a single length (approx. 290 m) of extruded aluminium. The coils have arrived at CERN; one of them is seen here being unloaded above the LHCb experimental cavern.

  2. Initial arch wires for alignment of crooked teeth with fixed orthodontic braces.

    LENUS (Irish Health Repository)

    Wang, Yan

    2010-01-01

    The initial arch wire is the first arch wire to be inserted into the fixed appliance at the beginning of orthodontic treatment and is used mainly for correcting crowding and rotations of teeth. With a number of orthodontic arch wires available for initial tooth alignment, it is important to understand which wire is most efficient, as well as which wires cause the least amount of root resorption and pain during the initial aligning stage of treatment.

  3. Structural mapping of the coiled-coil domain of a bacterial condensin and comparative analyses across all domains of life suggest conserved features of SMC proteins.

    Science.gov (United States)

    Waldman, Vincent M; Stanage, Tyler H; Mims, Alexandra; Norden, Ian S; Oakley, Martha G

    2015-06-01

    The structural maintenance of chromosomes (SMC) proteins form the cores of multisubunit complexes that are required for the segregation and global organization of chromosomes in all domains of life. These proteins share a common domain structure in which N- and C- terminal regions pack against one another to form a globular ATPase domain. This "head" domain is connected to a central, globular, "hinge" or dimerization domain by a long, antiparallel coiled coil. To date, most efforts for structural characterization of SMC proteins have focused on the globular domains. Recently, however, we developed a method to map interstrand interactions in the 50-nm coiled-coil domain of MukB, the divergent SMC protein found in γ-proteobacteria. Here, we apply that technique to map the structure of the Bacillus subtilis SMC (BsSMC) coiled-coil domain. We find that, in contrast to the relatively complicated coiled-coil domain of MukB, the BsSMC domain is nearly continuous, with only two detectable coiled-coil interruptions. Near the middle of the domain is a break in coiled-coil structure in which there are three more residues on the C-terminal strand than on the N-terminal strand. Close to the head domain, there is a second break with a significantly longer insertion on the same strand. These results provide an experience base that allows an informed interpretation of the output of coiled-coil prediction algorithms for this family of proteins. A comparison of such predictions suggests that these coiled-coil deviations are highly conserved across SMC types in a wide variety of organisms, including humans. © 2015 Wiley Periodicals, Inc.

  4. Surface coil magnetic resonance imaging.

    Science.gov (United States)

    Axel, L; Hayes, C

    1985-12-01

    Detection of MR signals with surface coils provides increased signal-to-noise ratio for superficial structures relative to detection by circumferential coils, permitting improved spatial resolution. Different geometries of surface coils can be used for different regions. Coils that are flat or curved to fit body contours are good for general imaging, with a range of coil sizes useful for structures of different size or depth. Solenoidal coils are useful for imaging protruding structures such as breasts, while smaller versions of conventional circumferential coils that can be slipped over limbs are useful for imaging extremities.

  5. AC loss in superconducting wires operating in a wind turbine like generator

    DEFF Research Database (Denmark)

    Seiler, Eugen; Zirngibl, Thomas; Mijatovic, Nenad

    2010-01-01

    We have manufactured a small circular superconducting coil impregnated with epoxy fibreglass. The coil was wound from a Bi-2223/Ag superconducting wire and it was tested in liquid nitrogen at 77 K. Current-voltage characteristic and the AC losses of the coil were measured and compared with the me...... resulted in the same AC loss characteristic. This work was done as a part of the Superwind project which aims to build a series of test coils and a spinning model of a generator to investigate AC loss and stability of the coils in wind turbine like conditions....

  6. Fine-Filament MgB2 Superconductor Wire

    Science.gov (United States)

    Cantu, Sherrie

    2015-01-01

    Hyper Tech Research, Inc., has developed fine-filament magnesium diboride (MgB2) superconductor wire for motors and generators used in turboelectric aircraft propulsion systems. In Phase I of the project, Hyper Tech demonstrated that MgB2 multifilament wires (superconductor and engineering current density and AC losses. Hyper Tech also fabricated MgB2 rotor coil packs for a superconducting generator. The ultimate goal is to enable low-cost, round, lightweight, low-AC-loss superconductors for motor and generator stator coils operating at 25 K in next-generation turboelectric aircraft propulsion systems.

  7. Usefulness of multifunctional gastrointestinal coil catheter for colorectal stent placement

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Tae-Hyung; Shin, Ji Hoon; Kim, Jin Hyoung; Lim, Jin-Oh; Kim, Kyung Rae [Asan Medical Center, Radiology and Research Institute of Radiology, Seoul (Korea); Song, Ho-Young [Asan Medical Center - Radiology, Songpa-gu, Seoul (Korea); Park, In Kook [Dongguk University, Life Science, Seoul (Korea); Choi, Eugene K. [Weill Medical College of Cornell University, New York, NY (United States)

    2008-11-15

    The purpose of this study was to evaluate the usefulness of a multifunctional gastrointestinal coil catheter for stent placement in 98 patients with colorectal strictures. The catheter was used in 98 consecutive patients for stent placement in the rectum (n = 24), recto-sigmoid (n = 13), sigmoid (n = 38), descending (n = 6), transverse (n = 11), splenic flexure (n = 3), hepatic flexure (n = 2), and ascending (n = 1) colon. The catheter was made of a stainless steel coil (1.3 mm in inner diameter), a 0.4-mm nitinol wire, a polyolefin tube, and a hemostasis valve. Usefulness of the catheter was evaluated depending on whether the catheter could pass a stricture over a guide wire and whether measurement of the stricture length was possible. The passage of the catheter over a guide wire beyond the stricture was technically successful and well tolerated in 93 (94.9%) of 98 patients. In the failed five patients, it was not possible to negotiate the guide wire due to presence of nearly complete small bowel obstruction. The average length of stricture was 6.15 cm (range, 3 cm to 20 cm) in patients with the colorectal stricture. There were no procedure-related complications. In conclusion, the multifunctional coil catheter seems to be useful in colorectal stent placement. (orig.)

  8. Acoustic emission induced from a vibrating winding at coil ends of an alternating current superconducting coil; Koryu chodendo koiru no koiru tan shindo to AE shingo

    Energy Technology Data Exchange (ETDEWEB)

    Arai, K.; Yamaguchi, H.; Kaiho, K. [Electrotechnical Lab., Tsukuba (Japan); Minomiya, A.; Ishigooka, T. [Seikei Univ., Tokyo (Japan); Fuji, H.; Saito, T. [Fujikura Ltd., Tokyo (Japan)

    2000-05-29

    Superconducting coil is liable to be subject to disturbances, and its stability is lowered by movement of wire, AC loss and longitudinal magnetic field effect. Since AE measurement can detect acoustic signal generated from superconducting winding via winding frame, there is no need to attach sensors directly to superconducting winding, and disturbances do not occur. In this study, AE signal caused by vibration of coil ends of NbTi AC coil was examined. Superconducting coils were prepared using NbTi elementary wire, FRP winding frame and spacer, AC current of 50 Hz was increased at a rate of 0.98 A/s in liquid helium, and envelope wave forms of AE signal was collected with AE sensor. Though slight periodical AE was observed in a steady condition, it was normally in low level and vibration was found being controlled. (NEDO)

  9. Bi-based HTS insert coils at high stress levels

    NARCIS (Netherlands)

    Weijers, H.W.; Schwartz, J.; ten Haken, Bernard

    2002-01-01

    Bi-2212 and Bi-2223 conductors from commercial sources are wound into double pancakes using the react and wind approach. One of the Bi-2223 conductors as supplied is reinforced with stainless steel strips. I–V characterization at 4.2 K until failure of the pancakes, in a 19 T–0.17 m cold bore magnet

  10. Sample of superconducting wiring from the LHC

    CERN Document Server

    The high magnetic fields needed for guiding particles around the Large Hadron Collider (LHC) ring are created by passing 12’500 amps of current through coils of superconducting wiring. At very low temperatures, superconductors have no electrical resistance and therefore no power loss. The LHC is the largest superconducting installation ever built. The magnetic field must also be extremely uniform. This means the current flowing in the coils has to be very precisely controlled. Indeed, nowhere before has such precision been achieved at such high currents. Magnet coils are made of copper-clad niobium–titanium cables — each wire in the cable consists of 9’000 niobium–titanium filaments ten times finer than a hair. The cables carry up to 12’500 amps and must withstand enormous electromagnetic forces. At full field, the force on one metre of magnet is comparable to the weight of a jumbo jet. Coil winding requires great care to prevent movements as the field changes. Friction can create hot spots wh...

  11. Mechanical properties of ITER coil CICC steel jackets production

    NARCIS (Netherlands)

    Romano, Gennaro; Vostner, Alexander; Bessette, Denis; Pong, Ian; Bevillard, Gregory; Zhou, Chao; Devred, Arnaud

    2016-01-01

    ITER cable-in-conduit conductor (CICC) used in the superconducting magnet system consists of a cable made of Nb3Sn or Nb-Ti strands inserted in a stainless steel tube (called jacket or conduit). Depending on the coil type, the jacket material is either made of a low carbon AISI 316LN (for toroidal

  12. Restoration of Fertility after Removal of Extrauterine Mirena Coil: A Case Report and Review of the Literature

    Directory of Open Access Journals (Sweden)

    Smriti R. C. Bhatta

    2011-01-01

    Full Text Available We present the case of a 27-year-old lady who was seen in the infertility clinic with a history of secondary infertility of a one-year duration. She had a hysteroscopy and Mirena insertion for heavy periods. Coil strings were not found by the GP during first coil check six weeks after insertion. A pelvic ultrasound scan did not show any coil, and it was not investigated further with a possible diagnosis of coil expulsion made. One year following that, she was seen in the infertility clinic. Initial investigations revealed anovulation, and HSG located the coil to be extrauterine. Mirena was removed laparoscopically, and a month following the removal she conceived. She is currently pregnant. This case highlights the effect of extrauterine mirena coils on fertility by possibly causing higher plasma levels of levonorgesterol and resulting suppression of ovulation. Laparoscopic removal of mirena coil can help in restoration of fertility.

  13. Progress of the ITER Correction Coils in China

    CERN Document Server

    Wei, J; Han, S; Yu, X; Du, S; Li, C; Fang, C; Wang, L; Zheng, W; Liu, L; Wen, J; Li, H; Libeyre, P; Dolgetta, N; Cormany, C; Sgobba, S

    2014-01-01

    The ITER Correction Coils (CC) include three sets of six coils each, distributed symmetrically around the tokamak to correct error fields. Each pair of coils, located on opposite sides of the tokamak, is series connected with polarity to produce asymmetric fields. The manufacturing of these superconducting coils is undergoing qualification of the main fabrication processes: winding into multiple pancakes, welding helium inlet/outlet on the conductor jacket, turn and ground insulation, vacuum pressure impregnation, inserting into an austenitic stainless steel case, enclosure welding, and assembling the terminal service box. It has been proceeding by an intense phase of R\\&D, trials tests, and final adjustment of the tooling. This paper mainly describes the progress in ASIPP for the CC manufacturing process before and on qualification phase and the status of corresponding equipment which are ordered or designed for each process. Some test results for the key component and procedure are also presented.

  14. Meiosis specific coiled-coil proteins in Shizosaccharomyces pombe

    Directory of Open Access Journals (Sweden)

    Okuzaki Daisuke

    2007-05-01

    Full Text Available Abstract Many meiosis-specific proteins in Schizosaccharomyces pombe contain coiled-coil motifs which play essential roles for meiotic progression. For example, the coiled-coil motifs present in Meu13 and Mcp7 are required for their function as a putative recombinase cofactor complex during meiotic recombination. Mcp6/Hrs1 and Mcp5/Num1 control horsetail chromosome movement by astral microtubule organization and anchoring dynein respectively. Dhc1 and Ssm4 are also required for horsetail chromosome movement. It is clear from these examples that the coiled-coil motif in these proteins plays an important role during the progression of cells through meiosis. However, there are still many unanswered questions on how these proteins operate. In this paper, we briefly review recent studies on the meiotic coiled-coil proteins in Sz. pombe.

  15. Description of CBETA magnet tuning wire holders

    Energy Technology Data Exchange (ETDEWEB)

    Brooks, S. [Brookhaven National Lab. (BNL), Upton, NY (United States)

    2017-07-19

    A non-­magnetic insert will be placed directly inside the permanent magnet blocks in every CBETA Halbach magnet in order to hold a set of iron “tuning wires”. These wires have various lengths around the perimeter of the aperture in order to cancel multipole field errors from the permanent magnet blocks.

  16. Improvement in stability of superconducting coil by different mechanical properties of bobbins

    Science.gov (United States)

    Sekine, N.; Takao, T.; Kojo, Y.; Yamaguchi, Y.; Tada, S.; Takeo, M.; Sato, S.; Yamanaka, A.; Fukui, S.

    2003-10-01

    The Dyneema ® fiber reinforced plastic (DFRP) expands to a direction of the Dyneema fibers during cooling process. Therefore, a winding angle in Dyneema fibers of the DFRP bobbin manufactured by the filament winding method makes possible to control thermal expansion/contraction properties to the circumferential direction on the bobbin. Moreover, DFRP’s frictional coefficients are considerably low. These properties are extremely different from those of GFRP which is generally used as the spacers and the bobbins of superconducting coils. In this paper, the coils fabricated with DFRP and GFRP bobbins are examined in DC and AC operating experiments. When the coil was operated under DC current, the low frictional properties of the coils having DFRP bobbins improved the instability due to the wire motion, on the other hand, in case of AC operating test, the thermal expansion properties of DFRP bobbin could reduce the mechanical losses between the wire and the bobbin.

  17. Improvement in stability of superconducting coil by different mechanical properties of bobbins

    Energy Technology Data Exchange (ETDEWEB)

    Sekine, N.; Takao, T.; Kojo, Y.; Yamaguchi, Y.; Tada, S.; Takeo, M.; Sato, S.; Yamanaka, A.; Fukui, S

    2003-10-15

    The Dyneema fiber reinforced plastic (DFRP) expands to a direction of the Dyneema fibers during cooling process. Therefore, a winding angle in Dyneema fibers of the DFRP bobbin manufactured by the filament winding method makes possible to control thermal expansion/contraction properties to the circumferential direction on the bobbin. Moreover, DFRP's frictional coefficients are considerably low. These properties are extremely different from those of GFRP which is generally used as the spacers and the bobbins of superconducting coils. In this paper, the coils fabricated with DFRP and GFRP bobbins are examined in DC and AC operating experiments. When the coil was operated under DC current, the low frictional properties of the coils having DFRP bobbins improved the instability due to the wire motion, on the other hand, in case of AC operating test, the thermal expansion properties of DFRP bobbin could reduce the mechanical losses between the wire and the bobbin.

  18. Automatic wire twister.

    Science.gov (United States)

    Smith, J F; Rodeheaver, G T; Thacker, J G; Morgan, R F; Chang, D E; Fariss, B L; Edlich, R F

    1988-06-01

    This automatic wire twister used in surgery consists of a 6-inch needle holder attached to a twisting mechanism. The major advantage of this device is that it twists wires significantly more rapidly than the conventional manual techniques. Testing has found that the ultimate force required to disrupt the wires twisted by either the automatic wire twister or manual techniques did not differ significantly and was directly related to the number of twists. The automatic wire twister reduces the time needed for wire twisting without altering the security of the twisted wire.

  19. Convex optimisation of gradient and shim coil winding patterns.

    Science.gov (United States)

    Poole, Michael S; Shah, N Jon

    2014-07-01

    Gradient and shim coils were designed using boundary element methods with convex optimisation. The convex optimisation framework permits the prototyping of many different cost functions and constraints, for example ℓ(p)-norms of the current density. Several examples of gradients and shims were designed and simulated to demonstrate this, as well as to investigate the behaviour of new cost functions. A mixture of ℓ(1)- and ℓ(∞)-norms of the current density, when used as a regularisation term in the field synthesis problem, was found to produce coils with bunches of equally spaced windings that do not take up all of the available surface. This is thought to be beneficial in the design of coils that will be manufactured from wire with a fixed cross-section. Copyright © 2014 Elsevier Inc. All rights reserved.

  20. Stretched Wire Mechanics

    Energy Technology Data Exchange (ETDEWEB)

    Bowden, Gordon; /SLAC

    2005-09-06

    Stretched wires are beginning to play an important role in the alignment of accelerators and synchrotron light sources. Stretched wires are proposed for the alignment of the 130 meter long LCLS undulator. Wire position technology has reached sub-micron resolution yet analyses of perturbations to wire straightness are hard to find. This paper considers possible deviations of stretched wire from the simple 2-dimensional catenary form.

  1. Quench and stress coupled analysis of high temperature superconducting coils

    Science.gov (United States)

    Li, Jessica; Zhai, Yuhu

    2017-10-01

    High-temperature superconductors (HTS) are promising candidates for compact next step fusion reactor designs due to their low power loss, higher margin and ability to carry extremely high current densities at high magnetic fields. However, unlike their low-temperature counterparts, HTS coils are much more vulnerable to damage during quench events under severe mechanical loading at high field magnet operation. It has been shown that the intensity of quench events may be mitigated by installing inductively coupled inserts around the superconducting coils. To this end, some previously explored designs of force-balanced coils which minimize stress in coil winding packs are reviewed for better stress management in HTS coils for quench mitigation. We use analytic models in FORTRAN and MATLAB to calculate the magnetic fields and resultant forces for various solenoid-like configurations of both high- and low-temperature superconducting coils. We then simulate their thermal, electric, and magnetic behaviors during quench-like events to identify optimal designs for both stability and quench protection.

  2. Measurement of AC losses in superconducting wires under external transverse magnetic field; Chodendo senzai no gaibu yoko jikai ka ni okeru koryu sonshitsu sokutei

    Energy Technology Data Exchange (ETDEWEB)

    Kakiuchi, T.; Arakawa, K.; Kawabata, S.; Sumiyoshi, F. [Kagoshima Univ., Kagoshima (Japan)

    2000-05-29

    The quantitative evaluation of ac loss characteristics of the superconducting wire material is very important, when little-loss design of the superconducting wire rod and application to the superconductive equipment are considered. Though in the case of this loss measurement in the pick-up coil method, the solenoidal coil state does the winding of the material wire rod, the loss characteristic measured by the interaction between winding changes, when coil shape such as roll pitch and number of layers of the sample coil change. Then, the purpose of this study is to clarify the effect of the shape of the sample coil to the loss characteristic in loss measurement under the outside transverse field by the pick-up coil method. (NEDO)

  3. Zylon-reinforced high magnetic field coils for the K.U. Leuven pulsed field laboratory

    Science.gov (United States)

    Rosseel, K.; Herlach, F.; Boon, W.; Bruynseraede, Y.

    2001-01-01

    PBO Zylon ® fibers have been used for the internal reinforcement of pulsed magnets. Due to the very high packing density (80%) of these fibers, vacuum impregnation of Zylon reinforced coils is difficult. Impregnation test were performed using pressure-vacuum impregnation and wet winding. A prototype series of coils for 60-70 T with 1-2 ms pulse duration was designed and wound, using wet winding for both the internal Zylon and external carbon fiber reinforcement. Special precautions were taken to avoid insulation breakdown at the transitions between conductor layers. Furthermore, axial movement of the conductor wires was restrained by strong axial compression of the coil with a steel shell casing. These modifications were incorporated into an 80 T coil made of Zylon and soft Cu. The design, construction and performance of this coil are discussed.

  4. AC losses of high T{sub c} superconducting coils; Koon chodendo koiru no koryu sonshitsu

    Energy Technology Data Exchange (ETDEWEB)

    Yokoyama, S.; Fukuda, M.; Kawagoe, A.; Sumiyoshi, F. [Kagoshima Univ., Kagoshima (Japan); Hayashi, H.; Irie, F. [Kyushu Electric Power Co., Inc., Fukuoka (Japan)

    2000-05-29

    High temperature superconductive coil expected for future application to electric power equipment has a defect of large AC loss that is a large obstacle for future practicalization. In this study, 13 double pancake coils were experimentally manufactured using Bi-2223 multicore tape wire, and their AC loss characteristics in liquid nitrogen were evaluated. In loss measurement, sample coils were placed in liquid nitrogen, and pure loss components contained in voltage between terminals were detected by lock-in amplifier. Loss characteristics of 3 coils tested all had strong frequency dependency. Though characteristic curve of overcurrent loss of silver which was normal conductive in low current region was conspicuously observed, their absolute values and critical frequency were different depending on coil. (NEDO)

  5. Integrated flexible ocular coil for power and data transfer in retinal prostheses.

    Science.gov (United States)

    Li, W; Rodger, D; Weiland, J; Humayun, M; Tai, Y

    2005-01-01

    A microfabricated and fully-implantable coil for use as a power and data transfer component for retinal prostheses is presented. Compared with traditional hand-made ocular coils, this parylene-based device is thin and flexible with 10 turns of thin-film metal wires and a thickness of less than 10 μm. In addition, the entire coil structure can be heat-formed on a mold to match the eye's curvature for extraocular implantation. Because it is made using parylene thin-film technology, this coil can be directly integrated with multielectrode arrays and with parylene-based packages incorporating application specific integrated circuits (ASICs) or discrete electrical components such as chip capacitors. This coil thus enables the fabrication and implantation of a fully microfabricated system for retinal prostheses.

  6. A Novel Method for Super-selective Coil Embolization Using an Extremely Soft Bare Coil through a Liquid Embolic Delivery Microcatheter

    Science.gov (United States)

    HORIE, Nobutaka; HAYASHI, Kentaro; MORIKAWA, Minoru; IZUMO, Tsuyoshi; NAGATA, Izumi

    Endovascular coil embolization for intracranial aneurysms, arteriovenous malformations (AVMs), dural arteriovenous fistulas (AVFs), and hypervascular tumors are recognized as an effective adjunctive or curative treatment. In this setting, it is sometimes difficult to navigate a coil delivery microcatheter to the target point of a tiny, tortuous vessel. We herein present a case series of a novel method that enabled super-selective coil embolization using an extremely soft bare, electrodetachable coil (ED extrasoft® coil) through a liquid embolic delivery microcatheter (Marathon®). The Marathon® catheter was successfully placed at the target point of the tiny, tortuous vessel, and coil embolization was achieved in all 16 patients with 9 AVMs, 2 distal aneurysms, 2 AVFs, and 3 meningiomas. The primary ED extrasoft® coil and delivery wire have a very small radius, and the coil is rapidly detachable with an alarm notice from the generator even under Marathon® with one marker. We believe that this technique can provide safe and efficient embolization for selected patients. PMID:24670315

  7. Analysis of reflection-coefficient by wireless power transmission using superconducting coils

    Energy Technology Data Exchange (ETDEWEB)

    Jeong, In Sung; Choi, Hyo Sang [Chosun University, Gwangju (Korea, Republic of); Chung, Dong Chul [Korea Institute of Carbon Convergence Technology, Jeonju (Korea, Republic of)

    2017-06-15

    The use of electronic devices such as mobile phones and tablet PCs has increased of late. However, the power which is supplied through wires has a limitation of the free use of devices and portability. Magnetic-resonance wireless power transfer (WPT) can achieve increased transfer distance and efficiency compared to the existing electromagnetic inductive coupling. A superconducting coil can be applied to increase the efficiency and distance of magnetic-resonance WPT. As superconducting coils have lower resistance than copper coils, they can increase the quality factor (Q-factor) and can overcome the limitations of magnetic-resonance WPT. In this study, copper coils were made from ordinary copper under the same condition as the superconducting coils for a comparison experiment. Superconducting coils use liquid nitrogen to keep the critical temperature. As there is a difference of medium between liquid nitrogen and air, liquid nitrogen was also used in the normal conductor coil to compare the experiment with under the same condition. It was confirmed that superconducting coils have a lower reflection-coefficient(S11) than the normal conductor coils.

  8. Asymmetric gradient coil design for use in a short, open bore magnetic resonance imaging scanner

    Science.gov (United States)

    Wang, Yaohui; Liu, Feng; Li, Yu; Tang, Fangfang; Crozier, Stuart

    2016-08-01

    A conventional cylindrical whole-body MRI scanner has a long bore that may cause claustrophobia for some patients in addition to being inconvenient for healthcare workers accessing the patient. A short-bore scanner usually offers a small sized imaging area, which is impractical for imaging some body parts, such as the torso. This work proposes a novel asymmetric gradient coil design that offers a full-sized imaging area close to one end of the coil. In the new design, the primary and shielding coils are connected at one end whilst separated at the other, allowing the installation of the cooling system and shim trays. The proposed coils have a larger wire gap, higher efficiency, lower inductance, less resistance and a higher figure of merit than the non-connected coils. This half-connected coil structure not only improves the coils' electromagnetic performance, but also slightly attenuates acoustic radiation at most frequencies when compared to a non-connected gradient coil. It is also quieter in some frequency bands than a conventional symmetric gradient coil.

  9. Coils in a nutshell: a review of coil physical properties.

    Science.gov (United States)

    White, J B; Ken, C G M; Cloft, H J; Kallmes, D F

    2008-08-01

    Since its inception, endovascular coil technology has grown substantially as multiple manufacturers entered the market with an ever-increasing number of new products. Practitioners are now inundated with a choice of coils that vary on the basis of factors such as size, composition, stiffness, and detachment mechanism. The seasoned interventionalist had the benefit of evolving with this technology and, therefore, is likely to understand many of the practical nuances of coil development; for more junior practitioners, who did not experience the ongoing changes in technology, this review will provide a basic framework for the fundamentals of coil design.

  10. Wire bonding in microelectronics

    CERN Document Server

    Harman, George G

    2010-01-01

    Wire Bonding in Microelectronics, Third Edition, has been thoroughly revised to help you meet the challenges of today's small-scale and fine-pitch microelectronics. This authoritative guide covers every aspect of designing, manufacturing, and evaluating wire bonds engineered with cutting-edge techniques. In addition to gaining a full grasp of bonding technology, you'll learn how to create reliable bonds at exceedingly high yields, test wire bonds, solve common bonding problems, implement molecular cleaning methods, and much more. Coverage includes: Ultrasonic bonding systems and technologies, including high-frequency systems Bonding wire metallurgy and characteristics, including copper wire Wire bond testing Gold-aluminum intermetallic compounds and other interface reactions Gold and nickel-based bond pad plating materials and problems Cleaning to improve bondability and reliability Mechanical problems in wire bonding High-yield, fine-pitch, specialized-looping, soft-substrate, and extreme-temperature wire bo...

  11. Laser Wire Stripper

    Science.gov (United States)

    1983-01-01

    NASA-developed space shuttle technology is used in a laser wire stripper designed by Raytheon Company. Laser beams cut through insulation on a wire without damaging conductive metal, because laser radiation that melts plastic insulation is reflected by the metal. The laser process is fast, clean, precise and repeatable. It eliminates quality control problems and the expense of rejected wiring.

  12. Coil Optimization for HTS Machines

    DEFF Research Database (Denmark)

    Mijatovic, Nenad; Jensen, Bogi Bech; Abrahamsen, Asger Bech

    An optimization approach of HTS coils in HTS synchronous machines (SM) is presented. The optimization is aimed at high power SM suitable for direct driven wind turbines applications. The optimization process was applied to a general radial flux machine with a peak air gap flux density of ~3T...... is suitable for which coil segment is presented. Thus, the performed study gives valuable input for the coil design of HTS machines ensuring optimal usage of HTS tapes....

  13. Design and Performance of the First Dual-Coil Magnet at the Wuhan National High Magnetic Field Center

    Science.gov (United States)

    Peng, T.; Sun, Q. Q.; Zhang, X.; Xu, Q.; Xiao, H. X.; Herlach, F.; Pan, Y.; Li, L.

    2013-03-01

    The first 80 T dual-coil magnet was manufactured and tested at the Wuhan National High Magnetic Field Center (WHMFC). The inner coil consists of 8 layers of 2.8 mm × 4.3 mm CuNb microcomposite wire developed in China; the bore diameter is 14 mm and the outer diameter 135 mm. The outer coil was wound directly on the inner coil with 12 layers of 3 mm × 6 mm soft copper. Each conductor layer of both coils was reinforced by Zylon/epoxy composite. The inner and outer coil were driven by a 1.6 MJ/5.12 mF capacitor bank and by eight 1 MJ/3.2 mF modules, respectively. At the voltage of 14.3 kV for the inner coil and 22 kV for the outer coil, the inner and outer coils produced peak fields of 48.5 T and 34.5 T respectively, which gave a total field of 83 T. This was the first combined operation of the new capacitor banks installed at the WHMFC. We present details of the design, manufacture and test of the dual-coil magnet and discuss crucial material properties. Based on this experience, a second dual-coil magnet will be designed; the enhanced design will be discussed. With the total energy of 12.6 MJ, peak field up to 90 T is expected.

  14. Flicking-wire drag tensioner

    Science.gov (United States)

    Dassele, M. A.; Fairall, H.

    1978-01-01

    Wire-drag system improves wire profile and applies consistent drag to wire. Wire drag is continuously adjustable from zero drag to tensile strength of wire. No-sag wire drag is easier to thread than former system and requires minimal downtime for cleaning and maintenance.

  15. Prototype ISR Superconducting Quadrupole for the low beta insertion.

    CERN Multimedia

    CERN PhotoLab

    1976-01-01

    The four coils are provisionally kept together by aluminium clamps while epoxy-glass bands are wrapped around them to form a number of spacer rings.Stainless steel spacers were then inserted between these rings and the yoke quadrants. The persons are Michel Bouvier(left) and Pierre Pugin. See also7702690X.

  16. PS wire chamber

    CERN Multimedia

    1970-01-01

    A wire chamber used at CERN's Proton Synchrotron accelerator in the 1970s. Multi-wire detectors contain layers of positively and negatively charged wires enclosed in a chamber full of gas. A charged particle passing through the chamber knocks negatively charged electrons out of atoms in the gas, leaving behind positive ions. The electrons are pulled towards the positively charged wires. They collide with other atoms on the way, producing an avalanche of electrons and ions. The movement of these electrons and ions induces an electric pulse in the wires which is collected by fast electronics. The size of the pulse is proportional to the energy loss of the original particle.

  17. Triple Halo Coil: Development and Comparison with Other TMS Coils

    Science.gov (United States)

    Rastogi, Priyam; Hadimani, Ravi; Jiles, David

    Transcranial Magnetic Stimulation (TMS) is a non-invasive stimulation technique that can be used for the treatment of various neurological disorders such as Parkinson's Disease, PTSD, TBI and anxiety by regulating synaptic activity. TMS is FDA approved for the treatment of major depressive disorder. There is a critical need to develop deep TMS coils that can stimulate deeper regions of the brain without excessively stimulating the cortex in order to provide an alternative to surgical methods. We have developed a novel multi-coil configuration called ``Triple Halo Coil'' (THC) that can stimulate deep brain regions. Investigation of induced electric and magnetic field in these regions have been achieved by computer modelling. Comparison of the results due to THC configuration have been conducted with other TMS coils such as ``Halo Coil'', circular coil and ``Figure of Eight'' coil. There was an improvement of more than 15 times in the strength of magnetic field, induced by THC configuration at 10 cm below the vertex of the head when compared with the ``Figure of Eight'' coil alone. Carver Charitable Trust.

  18. High-resolution structures of a heterochiral coiled coil.

    Science.gov (United States)

    Mortenson, David E; Steinkruger, Jay D; Kreitler, Dale F; Perroni, Dominic V; Sorenson, Gregory P; Huang, Lijun; Mittal, Ritesh; Yun, Hyun Gi; Travis, Benjamin R; Mahanthappa, Mahesh K; Forest, Katrina T; Gellman, Samuel H

    2015-10-27

    Interactions between polypeptide chains containing amino acid residues with opposite absolute configurations have long been a source of interest and speculation, but there is very little structural information for such heterochiral associations. The need to address this lacuna has grown in recent years because of increasing interest in the use of peptides generated from d amino acids (d peptides) as specific ligands for natural proteins, e.g., to inhibit deleterious protein-protein interactions. Coiled-coil interactions, between or among α-helices, represent the most common tertiary and quaternary packing motif in proteins. Heterochiral coiled-coil interactions were predicted over 50 years ago by Crick, and limited experimental data obtained in solution suggest that such interactions can indeed occur. To address the dearth of atomic-level structural characterization of heterochiral helix pairings, we report two independent crystal structures that elucidate coiled-coil packing between l- and d-peptide helices. Both structures resulted from racemic crystallization of a peptide corresponding to the transmembrane segment of the influenza M2 protein. Networks of canonical knobs-into-holes side-chain packing interactions are observed at each helical interface. However, the underlying patterns for these heterochiral coiled coils seem to deviate from the heptad sequence repeat that is characteristic of most homochiral analogs, with an apparent preference for a hendecad repeat pattern.

  19. Effect of wire shape on wire array discharge

    Energy Technology Data Exchange (ETDEWEB)

    Shimomura, N.; Tanaka, Y.; Yushita, Y.; Nagata, M. [University of Tokushima, Department of Electrical and Electronic Engineering, Tokushima (Japan); Teramoto, Y.; Katsuki, S.; Akiyama, H. [Kumamoto University, Department of Electrical and Computer Engineering, Kumamoto (Japan)

    2001-09-01

    Although considerable investigations have been reported on z-pinches to achieve nuclear fusion, little attention has been given from the point of view of how a wire array consisting of many parallel wires explodes. Instability existing in the wire array discharge has been shown. In this paper, the effect of wire shape in the wire array on unstable behavior of the wire array discharge is represented by numerical analysis. The claws on the wire formed in installation of wire may cause uniform current distribution on wire array. The effect of error of wire diameter in production is computed by Monte Carlo Method. (author)

  20. CCHMM_PROF: a HMM-based coiled-coil predictor with evolutionary information

    DEFF Research Database (Denmark)

    Bartoli, Lisa; Fariselli, Piero; Krogh, Anders

    2009-01-01

    MOTIVATION: The widespread coiled-coil structural motif in proteins is known to mediate a variety of biological interactions. Recognizing a coiled-coil containing sequence and locating its coiled-coil domains are key steps towards the determination of the protein structure and function. Different......://www.biocomp.unibo.it/ approximately lisa/coiled-coils. The predictor is freely available at http://gpcr.biocomp.unibo.it/cgi/predictors/cchmmprof/pred_cchmmprof.cgi. CONTACT: piero@biocomp.unibo.it....

  1. Central venous catheter insertion problem solving using intravenous catheter: technical communication

    Directory of Open Access Journals (Sweden)

    Alemohammad M

    2013-02-01

    Full Text Available Insertion of central venous catheter is an accepted method for hemodynamic monitor-ring, drug and fluid administration, intravenous access, hemodialysis and applying cardiac pace-maker in hospitalized patients. This procedure can be associated with severe complications. The aim of this article is to provide a practical approach to prevent catheter malposition in states that the guide wire will not pass freely.During central venous insertion in internal jugular vein using modified seldinger technique, when after venous insertion, the passage of the guide wire shows difficulties and don’t pass freely, insertion of an intravenous cannula over the wire and re-insertion of the wire can help to prevent malposition of the wire and the catheter. Use of an intravenous cannula over the guide, in situations that the guide wire cannot pass freely among the needle inserted in internal jugular vein, and re-insertion of the guide can probably prevent or reduce the tissue or vascular trauma and the associated complica-tions. This simple maneuver can be helpful in difficult cases especially in cardiac surgery patients who receive high dose heparin and it is necessary to avoid traumatize-tion of carotid artery.

  2. Intravascular placement of metallic coils as lung tumor markers for CyberKnife stereotactic radiation therapy

    Energy Technology Data Exchange (ETDEWEB)

    Karaman, Kutlay; Dokdok, A. Murat; Karadeniz, Okatay; Ceylan, Cemile; Engin, Kayihan [Anadolu Medical Center, Kocaeli (Turkey)

    2015-06-15

    To present our experience with placing endovascular coils in pulmonary arteries used as a fiducial marker for CyberKnife therapy and to describe the technical details and complications of the procedure. Between June 2005 and September 2013, 163 patients with primary or secondary lung malignancies, referred for fiducial placement for stereotactic radiosurgery, were retrospectively reviewed. Fourteen patients (9 men, 5 women; mean age, 70 years) with a history of pneumonectomy (n = 3), lobectomy (n = 3) or with severe cardiopulmonary co-morbidity (n = 8) underwent coil (fiducial marker) placement. Pushable or detachable platinum micro coils (n = 49) 2-3 mm in size were inserted through coaxial microcatheters into a small distal pulmonary artery in the vicinity of the tumor under biplane angiography/fluoroscopy guidance. Forty nine coils with a median number of 3 coils per tumor were placed with a mean tumor-coil distance of 2.7 cm. Forty three (87.7%) of 49 coils were successfully used as fiducial markers. Two coils could not be used due to a larger tumor-coil distance (> 50 mm). Four coils were in an acceptable position but their non-coiling shape precluded tumor tracking for CyberKnife treatment. No major complications needing further medication other than nominal therapy, hospitalization more than one night or permanent adverse sequale were observed. Endovascular placement of coil as a fiducial marker is safe and feasible during CyberKnife therapy, and might be an option for the patients in which percutaneous transthoracic fiducial placement might be risky.

  3. Wire + Arc Additive Manufacturing

    OpenAIRE

    Williams, Stewart W.; Martina, Filomeno; Addison, Adrian C.; Ding, Jialuo; Pardal, Goncalo; Colegrove, Paul A.

    2016-01-01

    Depositing large components (>10 kg) in titanium, aluminium, steel and other metals is possible using Wire + Arc Additive Manufacturing. This technology adopts arc welding tools and wire as feedstock for additive manufacturing purposes. High deposition rates, low material and equipment costs, and good structural integrity make Wire+Arc Additive Manufacturing a suitable candidate for replacing the current method of manufacturing from solid billets or large forgings, especially with regards to ...

  4. Charpak hemispherical wire chamber

    CERN Multimedia

    1970-01-01

    pieces. Mesures are of the largest one. Multi-wire detectors contain layers of positively and negatively charged wires enclosed in a chamber full of gas. A charged particle passing through the chamber knocks negatively charged electrons out of atoms in the gas, leaving behind positive ions. The electrons are pulled towards the positively charged wires. They collide with other atoms on the way, producing an avalanche of electrons and ions. The movement of these electrons and ions induces an electric pulse in the wires which is collected by fast electronics. The size of the pulse is proportional to the energy loss of the original particle.

  5. Photovoltaic Wire Project

    Data.gov (United States)

    National Aeronautics and Space Administration — This Small Business Innovation Research Phase I project will investigate a new architecture for photovoltaic devices based on nanotechnology: photovoltaic wire. The...

  6. Central Solenoid Insert Technical Specification

    Energy Technology Data Exchange (ETDEWEB)

    Martovetsky, Nicolai N [ORNL; Smirnov, Alexandre [ORNL

    2011-09-01

    The US ITER Project Office (USIPO) is responsible for the ITER central solenoid (CS) contribution to the ITER project. The Central Solenoid Insert (CSI) project will allow ITER validation the appropriate lengths of the conductors to be used in the full-scale CS coils under relevant conditions. The ITER Program plans to build and test a CSI to verify the performance of the CS conductor. The CSI is a one-layer solenoid with an inner diameter of 1.48 m and a height of 4.45 m between electric terminal ends. The coil weight with the terminals is approximately 820 kg without insulation. The major goal of the CSI is to measure the temperature margin of the CS under the ITER direct current (DC) operating conditions, including determining sensitivity to load cycles. Performance of the joints, ramp rate sensitivity, and stability against thermal or electromagnetic disturbances, electrical insulation, losses, and instrumentation are addressed separately and therefore are not major goals in this project. However, losses and joint performance will be tested during the CSI testing campaign. The USIPO will build the CSI that will be tested at the Central Solenoid Model Coil (CSMC) Test Facility at the Japan Atomic Energy Agency (JAEA), Naka, Japan. The industrial vendors (the Suppliers) will report to the USIPO (the Company). All approvals to proceed will be issued by the Company, which in some cases, as specified in this document, will also require the approval of the ITER Organization. Responsibilities and obligations will be covered by respective contracts between the USIPO, called Company interchangeably, and the industrial Prime Contractors, called Suppliers. Different stages of work may be performed by more than one Prime Contractor, as described in this specification. Technical requirements of the contract between the Company and the Prime Contractor will be covered by the Fabrication Specifications developed by the Prime Contractor based on this document and approved by

  7. 1998 wire development workshop proceedings

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-04-01

    This report consists of vugraphs of the presentations at the conference. The conference was divided into the following sessions: (1) First Generation Wire Development: Status and Issues; (2) First Generation Wire in Pre-Commercial Prototypes; (3) Second Generation Wire Development: Private Sector Progress and Issues; (4) Second Generation Wire Development: Federal Laboratories; and (5) Fundamental Research Issues for HTS Wire Development.

  8. Electrostatic determinants of stability in parallel 3-stranded coiled coils.

    Science.gov (United States)

    Roy, Liton; Case, Martin A

    2009-01-08

    The optimal positioning of salt-bridging interactions in a parallel alpha-helical homotrimeric coiled coil has been explored in a metal ion-assembled polypeptide trimer of 60 residues; arginine-glutamate pairs are more stabilizing than the corresponding lysine-glutamate pairs, and optimal stabilization is obtained with positively charged arginine residues at the c positions of the alpha-helical heptad and negatively charged glutamate residues at the e positions.

  9. Adhesion strength study of IBAD-MOCVD-based 2G HTS wire using a peel test

    Energy Technology Data Exchange (ETDEWEB)

    Zhang, Y., E-mail: yzhang@superpower-inc.com [SuperPower Inc., 450 Duane Avenue, Schenectady, NY 12304 (United States); Hazelton, D.W.; Knoll, A.R.; Duval, J.M.; Brownsey, P.; Repnoy, S.; Soloveichik, S.; Sundaram, A.; McClure, R.B. [SuperPower Inc., 450 Duane Avenue, Schenectady, NY 12304 (United States); Majkic, G.; Selvamanickam, V. [University of Houston, 4800 Calhoun Road, Houston, TX 77204 (United States)

    2012-02-15

    A peel test was used to study the adhesion strength of a commercial grade 2G HTS wire which features a characteristic multilayer structure with the rare earth-based MOCVD superconducting film deposited on an IBAD-MgO template. The peel test could be carried out at various peeling angles (from 90 Degree-Sign to 180 Degree-Sign) and the peel strength of a wire was defined as the steady-state peeling load determined from a load-displacement curve. The test results had good reproducibility and accuracy, making the test a reliable and useful method for studying the adhesion strength of the wire. By characterizing the peeled surfaces the weakest interface in a wire could be identified. The peel strength data of the wire was analyzed together with the performance of the experimental magnet coils fabricated using the wire. The effect of the silver contact layer annealing on the peel strength is discussed.

  10. AC loss properties of MgB{sub 2} multifilament wires

    Energy Technology Data Exchange (ETDEWEB)

    Tanaka, Kazuhide; Funaki, Kazuo; Sueyoshi, Takahiro; Sasashige, Yushi; Kajikawa, Kazuhiro; Iwakuma, Masataka [Kyushu University Graduate School of Information Science and Electrical Engineering, 744 Moto-oka, Nishi-ku, Fukuoka 819-0395 (Japan); Okada, Michiya [HRL Hitachi, Ltd, 7-1-1 Oomika, Hitachi 319-1292 (Japan); Kumakura, Hiroaki [National Institute for Materials Science, 1-2-1 Sengen, Tsukuba 305-0047 (Japan); Hayashi, Hidemi [Kyushu Electric Power Co., Incorporated, 2-1-47 Shiobaru, Minami-ku, Fukuoka 815-8520 (Japan)], E-mail: kazuhide.tanaka.je@hitachi.com

    2008-09-15

    We designed and fabricated two types of composite wires with 6 MgB{sub 2} filaments. One is a Cu-sheathed Nb-barrier wire and the other is a CuNi-sheathed Ta-barrier wire. The transverse-field losses of the trial wires were measured with a standardized pickup coil system in liquid helium. We evaluated the observed AC losses using two structural models, a multifilament conductor model and a hollow-cylindrical one. For the CuNi-sheathed Ta-barrier wire, the AC loss property can be explained by the usual model of multifilament conductors. Further reductions in AC loss can be expected by making the filaments thinner. For the Cu-sheathed Nb-barrier wire, theoretical considerations suggest the multifilament structure behaves as a hollow-cylindrical superconductor in the AC loss property. Thus, we need to pay particular attention to designing the barrier material for reduction in the AC loss.

  11. Coil for LEAR extraction septum

    CERN Multimedia

    CERN PhotoLab

    1982-01-01

    Which way does the current flow ? This intriguing object is the coil for the LEAR extraction septum. There were two septa, first a thin one, then this one, not so thin, somewhat on the borderline between septum and bending magnet.

  12. First coil for the SC

    CERN Multimedia

    CERN PhotoLab

    1955-01-01

    The coils for the SC magnet were stored in the large hangar of the Cointrin Airport (to make sure that they would be available before snow and ice would block the roads and canals from Belgium, where they were built).

  13. Transport in quantum wires

    Indian Academy of Sciences (India)

    This motivated us to study the LL model of a quantum wire, with Fermi liquid leads and the unusual feature of ... of quantized conductance even in clean quantum wires and a novel odd–even effect in the presence of a .... But in one dimension, it is well-known that the FL theory breaks down, and the ground state is a ...

  14. Commercial and Industrial Wiring.

    Science.gov (United States)

    Kaltwasser, Stan; Flowers, Gary

    This module is the third in a series of three wiring publications, includes additional technical knowledge and applications required for job entry in the commercial and industrial wiring trade. The module contains 15 instructional units that cover the following topics: blueprint reading and load calculations; tools and equipment; service;…

  15. Simulation and optimization of the magnetic field in an electroplated copper micro-coil

    Science.gov (United States)

    Matar, Maher; Al-Halhouli, Alaaldeen T.; Büttgenbach, Stephanus; Dietzel, Andreas H.

    2013-05-01

    This work aims at simulating and optimizing the magnetic field intensity in different electroplated copper micro-coil designs that can be integrated in a recently developed electromagnetic micro-pump. The results of this study will be used in fabricating new optimized micro-coil designs that may enhance the performance of the developed synchronous micro-pump (i.e., the maximum back pressures and flow rates). The synchronous micro-pump concept depends on managing the movement of two magnets in an annular fluidic channel. Magnet rotation is achieved by sequentially activating a set of planar micro-coils to repel or attract the first magnet (traveling magnet) through the channel, while the second one is anchored between the inlet and the outlet ports. At the end of each pumping cycle, the magnets exchange their anchored and traveling functions. To achieve the maximum back pressure and flow rate (highest performance) in such micro-pump, higher magnetic fields without exceeding the material temperature limitation are required. The stronger the magnetic fields that can be generated, the higher the hydraulic power that can the pump deliver. This study presents extensive numerical simulations using the commercial software package COMSOL and presents also optimizations for the effect of the main micro-coil parameters on the generated magnetic field: coil wire width and height, the coil turns offset distance, the effect of including an iron core inside the coil area, and the number of coil turns. The main analyzed results are: the normal magnetic flux contours at the top (upper) surface of the coil - where the permanent magnets rotate in the micro-pump channel -, the distribution of the magnetic field streams and the area averaging of the magnetic field intensity all over the micro-coil sector.

  16. Report of the SSC workshop on distributed multipole correction coils. Task force report

    Energy Technology Data Exchange (ETDEWEB)

    Sah, R. [ed.

    1988-01-01

    The SSC Workshop on Distributed Multipole Correction Coils was held at Brookhaven National Laboratory on October 13 and 14, 1987. This Workshop was organized by the SSC Central Design Group, and its purpose was to discuss the present status of specifications, designs, and R&D plans for distributed, actively-powered multipole correction coils for the SSC. The Workshop was organized into four consecutive sessions to discuss the following topics: requirements for distributed correction coils, distributed connection coil designs, materials issues, and plans for future R&D. The following conclusions were drawn from the workshop: Accelerator physics considerations indicate that distributed multipole correction coils represent a feasible and flexible method to correct magnetic field errors in the SSC. Considerable progress has been made by Brookhaven National Laboratory in collaboration with industry to develop a possible fabrication technique for distributed correction coils. This technique consists of imbedding superconducting wire in a flexible plastic substrate. Its feasibility for the SSC still needs to be demonstrated. BNL has presented a preliminary plan for the necessary R&D. A successful technique has been developed to manufacture distributed correction coils for HERA. The coil performance is excellent. As yet, no plan has been proposed to study this type of correction coil for the SSC. The results from an experiment to study radiation damage to organic materials, although still preliminary, am providing guidance in selecting the most radiation resistant materials to use in correction coils. The test samples in this experiment were subjected to much larger radiation doses than expected at the SSC. Considerable information on radiation damage is available in the literature.

  17. Controlled motion of domain walls in submicron amorphous wires

    Directory of Open Access Journals (Sweden)

    Mihai Ţibu

    2016-05-01

    Full Text Available Results on the control of the domain wall displacement in cylindrical Fe77.5Si7.5B15 amorphous glass-coated submicron wires prepared by rapid quenching from the melt are reported. The control methods have relied on conical notches with various depths, up to a few tens of nm, made in the glass coating and in the metallic nucleus using a focused ion beam (FIB system, and on the use of small nucleation coils at one of the sample ends in order to apply magnetic field pulses aimed to enhance the nucleation of reverse domains. The notch-based method is used for the first time in the case of cylindrical ultrathin wires. The results show that the most efficient technique of controlling the domain wall motion in this type of samples is the simultaneous use of notches and nucleation coils. Their effect depends on wire diameter, notch depth, its position on the wire length, and characteristics of the applied pulse.

  18. Controlled motion of domain walls in submicron amorphous wires

    Energy Technology Data Exchange (ETDEWEB)

    Ţibu, Mihai; Lostun, Mihaela; Rotărescu, Cristian; Atiţoaie, Alexandru; Lupu, Nicoleta; Óvári, Tibor-Adrian, E-mail: taovari@phys-iasi.ro; Chiriac, Horia [Department of Magnetic Materials and Devices, National Institute of Research and Development for Technical Physics, Iaşi, 700050 (Romania); Allwood, Dan A. [Department of Materials Science and Engineering, University of Sheffield, Sheffield, S1 3JD (United Kingdom)

    2016-05-15

    Results on the control of the domain wall displacement in cylindrical Fe{sub 77.5}Si{sub 7.5}B{sub 15} amorphous glass-coated submicron wires prepared by rapid quenching from the melt are reported. The control methods have relied on conical notches with various depths, up to a few tens of nm, made in the glass coating and in the metallic nucleus using a focused ion beam (FIB) system, and on the use of small nucleation coils at one of the sample ends in order to apply magnetic field pulses aimed to enhance the nucleation of reverse domains. The notch-based method is used for the first time in the case of cylindrical ultrathin wires. The results show that the most efficient technique of controlling the domain wall motion in this type of samples is the simultaneous use of notches and nucleation coils. Their effect depends on wire diameter, notch depth, its position on the wire length, and characteristics of the applied pulse.

  19. Reactive tissue proliferation and damage of elastic lamina caused by hydrogel coated coils in experimental rat aneurysms.

    Science.gov (United States)

    Zhang, Chao; Chaudhary, Neeraj; Gemmete, Joseph J; Thompson, B Gregory; Xi, Guohua; Pandey, Aditya S

    2014-07-01

    The HydroCoil Endovascular Aneurysm Occlusion and Packing Study clinical trial, comparing HydroCoil with platinum coils, reported an 8.6% reduction in significant recurrence following cerebral aneurysm coil embolization. We sought to better understand the mechanism of aneurysmal healing following HydroCoil implantation using the rat external carotid artery (ECA) sidewall aneurysm model. We ligated the proximal ECA, creating a blind pouch in our rat model. HydroCoil or bare platinum coil segments (5 mm) were inserted into aneurysms. Sham operated rats underwent identical procedures without coil insertion. 14 days after coil embolization, animals were sacrificed and the common carotid artery/internal carotid artery/ECA complex removed. Sac and surrounding vasculature underwent microscopic and histopathologic evaluation. Cellular and fibrotic components within the sac were defined as the organized area. Percentage of organized area and residual length of internal elastic lamina were calculated. Organized tissue area in ECA sac 2 weeks following coil embolization was significantly greater in the HydroCoil group than the bare coil (60.42±22.58% vs 15.62±19.24%; p=0.01) and sham (60.42±22.58% vs 4.61±3.86%; p=0.002) groups. Elastic lamina was significantly reduced in the HydroCoil group compared with the sham and bare coil groups (21.67±16.50% vs 100% and 96.06±8.78%; both pgroups for organized tissue formation or reduction in elastic lamina. Greater numbers of B cells, T cells, and neutrophils were present within HydroCoil induced organized tissue compared with the platinum group; this difference was not statistically significant. In the rat ECA sidewall aneurysm model, hydrogel coated coils cause more tissue reaction and organization compared with bare platinum coils, possibly attributed to observed elastic lamina damage and vascular smooth muscle cell proliferation. Published by the BMJ Publishing Group Limited. For permission to use (where not already

  20. Dry cryomagnetic system with MgB2 coil

    Science.gov (United States)

    Abin, D. A.; Mineev, N. A.; Osipov, M. A.; Pokrovskii, S. V.; Rudnev, I. A.

    2017-12-01

    MgB2 may be the future superconducting wire material for industrial magnets due to it’s higher operation temperature and potentially lower cost than low temperature superconductors (LTS) have. We designed a compact cryomagnetic system with the use of MgB2. The possibility of creating a magnet with a central field of 5 T from a commercial MgB2 wire by the “react and wound” method was investigated. The magnetic system is cooled by a cryocooler through a copper bus. The magnet has a warm bore diameter of 4 cm. The design of a magnet consisting of three concentric solenoids is proposed: an internal one of high-temperature superconductor (HTS), an average of MgB2, and an external of NbTi. The operating current of the system is 100 A. Two pairs of current leads are used. A separate pair of current leads for power supplying NbTi coil allows testing of MgB2 and HTS coils in an external field. The load curves for each of the magnets are calculated.

  1. Cerclage wiring technique after proximal femoral fracture in total hip arthroplasty.

    Science.gov (United States)

    Fishkin, Z; Han, S M; Ziv, I

    1999-01-01

    Cerclage wires have been used to stabilize proximal femoral cracks after stem insertion in cementless total hip arthroplasty. The objective of this study was to determine the optimal number and orientation of cerclage wires necessary to prevent stem subsidence and crack propagation. The crack was stabilized by 1, 2, or 3 wires placed either normal to the femoral neck axis or normal to the crack. The femora were compressed to 2,670 N while measuring crack opening and stem subsidence. Wires placed normal to the crack allowed less stem subsidence by 3.17 mm and less crack opening by 1.55 mm compared with wires placed normal to the neck. The addition of multiple wires reduced subsidence by 50% and reduced crack opening to <1 mm. Medial and anterior calcar cracks are best stabilized by at least 2 cerclage wires that are placed normal to the crack.

  2. The design study of the JT-60SU device. No. 3. The superconductor-coils of JT-60SU

    Energy Technology Data Exchange (ETDEWEB)

    Ushigusa, Kenkichi; Mori, Katsuharu; Nakagawa, Syouji [Japan Atomic Energy Research Inst., Naka, Ibaraki (Japan). Naka Fusion Research Establishment] [and others

    1997-03-01

    The superconducting coil systems and the cryogenic system for the JT-60 Super Upgrade (JT-60SU) has been designed. Both Nb{sub 3}Al and NbTi as a superconducting wire material are employed in the toroidal coils (D-shaped 18 coils) to realize a high field magnet with a low cost. Significant reduction of the coil weight (150 tons/coil) without losing the coil rigidity has been achieved by connecting two toroidal coils with shear panels. Validity of this design is confirmed by the detailed structural analysis and thermohydraulic analysis. The poloidal coil system consists of 4 central solenoid coils with (NbTi){sub 3}Sn and 6 outer equilibrium field coils with NbTi. This system has an enough capability to supply the flux of 170Vs to produce a 10MA discharge with 200s of flat-top and to make various plasma configurations. The construction procedure of the poloidal coil system is also established under the constraint of the JT-60 site. Two sets of race-track shaped superconducting coils mounted on the top of the machine is designed to compensate the error field inside the vessel by supplying helical (m=2/n=1) magnetic field. By using cryogenic system with a 36kW of cooling capacity, the total cold weight of around 4000tons can be cooled down to 4.5K within one month, and steady heat load of 6.5kW and transient heat load of 9.0MJ can be removed within 30 minutes of discharge repetition rate. (author)

  3. Ultrathin Nanocrystalline Magnetic Wires

    Directory of Open Access Journals (Sweden)

    Horia Chiriac

    2017-02-01

    Full Text Available The magnetic characteristics of FINEMET type glass-coated nanowires and submicron wires are investigated by taking into account the structural evolution induced by specific annealing all the way from a fully amorphous state to a nanocrystalline structure. The differences between the magnetic properties of these ultrathin wires and those of the thicker glass-coated microwires and “conventional” wires with similar structures have been emphasized and explained phenomenologically. The domain wall propagation in these novel nanowires and submicron wires, featuring a combination between an amorphous and a crystalline structure, has also been studied, given the recent interest in the preparation and investigation of new materials suitable for the development of domain wall logic applications.

  4. Dual wire weld feed proportioner

    Science.gov (United States)

    Nugent, R. E.

    1968-01-01

    Dual feed mechanism enables proportioning of two different weld feed wires during automated TIG welding to produce a weld alloy deposit of the desired composition. The wires are fed into the weld simultaneously. The relative feed rates of the wires and the wire diameters determine the weld deposit composition.

  5. The structure of the GemC1 coiled coil and its interaction with the Geminin family of coiled-coil proteins

    Energy Technology Data Exchange (ETDEWEB)

    Caillat, Christophe; Fish, Alexander [The Netherlands Cancer Institute, 1066 CX Amsterdam (Netherlands); Pefani, Dafni-Eleftheria; Taraviras, Stavros; Lygerou, Zoi [University of Patras, 26505 Rio, Patras (Greece); Perrakis, Anastassis, E-mail: a.perrakis@nki.nl [The Netherlands Cancer Institute, 1066 CX Amsterdam (Netherlands)

    2015-10-31

    The GemC1 coiled-coil structure has subtle differences compared with its homologues Geminin and Idas. Co-expression experiments in cells and biophysical stability analysis of the Geminin-family coiled coils suggest that the GemC1 coiled coil alone is unstable. GemC1, together with Idas and Geminin, an important regulator of DNA-replication licensing and differentiation decisions, constitute a superfamily sharing a homologous central coiled-coil domain. To better understand this family of proteins, the crystal structure of a GemC1 coiled-coil domain variant engineered for better solubility was determined to 2.2 Å resolution. GemC1 shows a less typical coiled coil compared with the Geminin homodimer and the Geminin–Idas heterodimer structures. It is also shown that both in vitro and in cells GemC1 interacts with Geminin through its coiled-coil domain, forming a heterodimer that is more stable that the GemC1 homodimer. Comparative analysis of the thermal stability of all of the possible superfamily complexes, using circular dichroism to follow the unfolding of the entire helix of the coiled coil, or intrinsic tryptophan fluorescence of a unique conserved N-terminal tryptophan, shows that the unfolding of the coiled coil is likely to take place from the C-terminus towards the N-terminus. It is also shown that homodimers show a single-state unfolding, while heterodimers show a two-state unfolding, suggesting that the dimer first falls apart and the helices then unfold according to the stability of each protein. The findings argue that Geminin-family members form homodimers and heterodimers between them, and this ability is likely to be important for modulating their function in cycling and differentiating cells.

  6. Prospective motion correction using inductively coupled wireless RF coils.

    Science.gov (United States)

    Ooi, Melvyn B; Aksoy, Murat; Maclaren, Julian; Watkins, Ronald D; Bammer, Roland

    2013-09-01

    A novel prospective motion correction technique for brain MRI is presented that uses miniature wireless radio-frequency coils, or "wireless markers," for position tracking. Each marker is free of traditional cable connections to the scanner. Instead, its signal is wirelessly linked to the MR receiver via inductive coupling with the head coil. Real-time tracking of rigid head motion is performed using a pair of glasses integrated with three wireless markers. A tracking pulse-sequence, combined with knowledge of the markers' unique geometrical arrangement, is used to measure their positions. Tracking data from the glasses is then used to prospectively update the orientation and position of the image-volume so that it follows the motion of the head. Wireless-marker position measurements were comparable to measurements using traditional wired radio-frequency tracking coils, with the standard deviation of the difference Wireless-marker safety was verified with B1 maps and temperature measurements. Prospective motion correction was demonstrated in a 2D spin-echo scan while the subject performed a series of deliberate head rotations. Prospective motion correction using wireless markers enables high quality images to be acquired even during bulk motions. Wireless markers are small, avoid radio-frequency safety risks from electrical cables, are not hampered by mechanical connections to the scanner, and require minimal setup times. These advantages may help to facilitate adoption in the clinic. Copyright © 2013 Wiley Periodicals, Inc.

  7. Prospective Motion Correction using Inductively-Coupled Wireless RF Coils

    Science.gov (United States)

    Ooi, Melvyn B.; Aksoy, Murat; Maclaren, Julian; Watkins, Ronald D.; Bammer, Roland

    2013-01-01

    Purpose A novel prospective motion correction technique for brain MRI is presented that uses miniature wireless radio-frequency (RF) coils, or “wireless markers”, for position tracking. Methods Each marker is free of traditional cable connections to the scanner. Instead, its signal is wirelessly linked to the MR receiver via inductive coupling with the head coil. Real-time tracking of rigid head motion is performed using a pair of glasses integrated with three wireless markers. A tracking pulse-sequence, combined with knowledge of the markers’ unique geometrical arrangement, is used to measure their positions. Tracking data from the glasses is then used to prospectively update the orientation and position of the image-volume so that it follows the motion of the head. Results Wireless-marker position measurements were comparable to measurements using traditional wired RF tracking coils, with the standard deviation of the difference wireless markers enables high quality images to be acquired even during bulk motions. Wireless markers are small, avoid RF safety risks from electrical cables, are not hampered by mechanical connections to the scanner, and require minimal setup times. These advantages may help to facilitate adoption in the clinic. PMID:23813444

  8. Seismic analysis of ITER fourth PF (Poloidal Field Coil) feeder

    Energy Technology Data Exchange (ETDEWEB)

    Liu, Sumei, E-mail: smliu@ipp.ac.cn [School of Engineering, Anhui Agricultural University, Hefei 230036 (China); Institute of Plasma Physics, Chinese Academy of Science, Hefei 230031 (China); Chen, Wei [School of Engineering, Anhui Agricultural University, Hefei 230036 (China); Song, Yuntao; Ni, Xiaojun; Wang, Zhongwei [Institute of Plasma Physics, Chinese Academy of Science, Hefei 230031 (China); Chen, Yonghua; Gong, Chenyu [Magnet Division, TKM, ITER Organization, Route de Vinon sur Verdon, 13115 St. Paul Lez Durance (France)

    2014-10-15

    The ITER feeder systems connect the ITER magnet systems located inside the main cryostat to the cryo-plant, power-supply and control system interfaces outside the cryostat. The main purpose of the feeders is to convey the cryogenic supply and electrical power to the coils as well as house the instrumentation wiring. The PF busbar which carries 52 kA current will suffer from high Lorentz force due to the background magnetic field inspired by the coils and the self-field between every pair of busbars. Except their mechanical strength and thermal insulation performance must be achieved, the dynamic mechanism on PF structure should be assessed. This paper presents the simulation and seismic analysis on ITER 4th PF feeder including the Coil Terminal Box and S-bend Box (CTB and SBB), the Cryostat Feed-through (CFT), the In-Cryostat-Feeder (ICF), especially for the ground supports and main outer-tube firstly. This analysis aims to study seismic resistance on system design under local seismograms with floor response spectrum, the structural response vibration mode and response duration results of displacement, membrane stress, and bending stress on structure under different directions actuating signals were obtained by using the single-seismic spectrum analysis and Dead Weight analysis respectively. Based on the simulative and analytical results, the system seismic resistance and the integrity of the support structure in the 4th PF feeder have been studied and the detail design confirmed.

  9. Copper wire bonding

    CERN Document Server

    Chauhan, Preeti S; Zhong, ZhaoWei; Pecht, Michael G

    2014-01-01

    This critical volume provides an in-depth presentation of copper wire bonding technologies, processes and equipment, along with the economic benefits and risks.  Due to the increasing cost of materials used to make electronic components, the electronics industry has been rapidly moving from high cost gold to significantly lower cost copper as a wire bonding material.  However, copper wire bonding has several process and reliability concerns due to its material properties.  Copper Wire Bonding book lays out the challenges involved in replacing gold with copper as a wire bond material, and includes the bonding process changes—bond force, electric flame off, current and ultrasonic energy optimization, and bonding tools and equipment changes for first and second bond formation.  In addition, the bond–pad metallurgies and the use of bare and palladium-coated copper wires on aluminum are presented, and gold, nickel and palladium surface finishes are discussed.  The book also discusses best practices and re...

  10. Tokamak Fusion Core Experiment: design studies based on superconducting and hybrid toroidal field coils. Design overview

    Energy Technology Data Exchange (ETDEWEB)

    Flanagan, C.A. (ed.)

    1984-10-01

    This document is a design overview that describes the scoping studies and preconceptual design effort performed in FY 1983 on the Tokamak Fusion Core Experiment (TFCX) class of device. These studies focussed on devices with all-superconducting toroidal field (TF) coils and on devices with superconducting TF coils supplemented with copper TF coil inserts located in the bore of the TF coils in the shield region. Each class of device is designed to satisfy the mission of ignition and long pulse equilibrium burn. Typical design parameters are: major radius = 3.75 m, minor radius = 1.0 m, field on axis = 4.5 T, plasma current = 7.0 MA. These designs relay on lower hybrid (LHRH) current rampup and heating to ignition using ion cyclotron range of frequency (ICRF). A pumped limiter has been assumed for impurity control. The present document is a design overview; a more detailed design description is contained in a companion document.

  11. Platinum (IV) coiled coil nanotubes selectively kill human glioblastoma cells.

    Science.gov (United States)

    Thanasupawat, Thatchawan; Bergen, Hugo; Hombach-Klonisch, Sabine; Krcek, Jerry; Ghavami, Saeid; Del Bigio, Marc R; Krawitz, Sherry; Stelmack, Gerald; Halayko, Andrew; McDougall, Matthew; Meier, Markus; Stetefeld, Jörg; Klonisch, Thomas

    2015-05-01

    Malignant glioma are often fatal and pose a significant therapeutic challenge. Here we have employed α-helical right handed coiled coils (RHCC) which self-assemble into tetrameric nanotubes that stably associate with platinum (Pt) (IV) compound. This Pt(IV)-RHCC complex showed superior in vitro and in vivo toxicity in human malignant glioma cells at up to 5 fold lower platinum concentrations when compared to free Pt(IV). Pt(IV)-RHCC nanotubes activated multiple cell death pathways in GB cells without affecting astrocytes in vitro or causing damage to normal mouse brain. This Pt(IV)-RHCC nanotubes may serve as a promising new therapeutic tool for low dose Pt(IV) prodrug application for highly efficient and selective treatment of human brain tumors. The prognosis of malignant glioma remains poor despite medical advances. Platinum, one of the chemotherapeutic agents used, has significant systemic side effects. In this article, the authors employed α-helical right handed coiled coil (RHCC) protein nanotubes as a carrier for cisplatin. It was shown that the new compound achieved higher tumor kill rate but lower toxicity to normal cells and thus may hold promise to be a highly efficient treatment for the future. Copyright © 2015 Elsevier Inc. All rights reserved.

  12. Design of Range Adaptive Wireless Power Transfer System Using Non-coaxial Coils

    Science.gov (United States)

    Yang, Dongsheng; Won, Sokhui; Hong, Huan

    2017-05-01

    Wireless Power Transfer (WPT) is a remarkable technology because of its convenience and applicability in harsh environment. Particularly, Magnetic Coupling WPT (MC-WPT) is a proper method to midrange power transfer, but the frequency splitting at over-coupling range, which is related with transfer distance, is challenge of transmission efficiency. In order to overcome this phenomenon, recently the range adaptive WPT is proposed. In this paper, we aim to the type with a set of non-coaxial driving coils, so that this may remove the connection wires from PA (Power Amplifier) to driving coil. And, when the radius of driving coil is changed, on the different gaps between driving and TX coils, coupling coefficient between these is computed in both cases of coaxial and non-coaxial configurations. In addition, the designing steps for 4-coil WPT system using non-coaxial coils are described with the example. Finally, the reliability of this topology has been proved and simulated with PSPICE.

  13. Static Measurements on HTS Coils of Fully Superconducting AC Electric Machines for Aircraft Electric Propulsion System

    Science.gov (United States)

    Choi, Benjamin B.; Hunker, Keith R.; Hartwig, Jason; Brown, Gerald V.

    2017-01-01

    The NASA Glenn Research Center (GRC) has been developing the high efficiency and high-power density superconducting (SC) electric machines in full support of electrified aircraft propulsion (EAP) systems for a future electric aircraft. A SC coil test rig has been designed and built to perform static and AC measurements on BSCCO, (RE)BCO, and YBCO high temperature superconducting (HTS) wire and coils at liquid nitrogen (LN2) temperature. In this paper, DC measurements on five SC coil configurations of various geometry in zero external magnetic field are measured to develop good measurement technique and to determine the critical current (Ic) and the sharpness (n value) of the super-to-normal transition. Also, standard procedures for coil design, fabrication, coil mounting, micro-volt measurement, cryogenic testing, current control, and data acquisition technique were established. Experimentally measured critical currents are compared with theoretical predicted values based on an electric-field criterion (Ec). Data here are essential to quantify the SC electric machine operation limits where the SC begins to exhibit non-zero resistance. All test data will be utilized to assess the feasibility of using HTS coils for the fully superconducting AC electric machine development for an aircraft electric propulsion system.

  14. Toward simultaneous PET/MR breast imaging: systematic evaluation and integration of a radiofrequency breast coil.

    Science.gov (United States)

    Aklan, Bassim; Paulus, Daniel H; Wenkel, Evelyn; Braun, Harald; Navalpakkam, Bharath K; Ziegler, Susanne; Geppert, Christian; Sigmund, Eric E; Melsaether, Amy; Quick, Harald H

    2013-02-01

    With the recent introduction of integrated whole-body hybrid positron emission tomography/magnetic resonance (PET/MR) scanners, simultaneous PET/MR breast imaging appears to be a potentially attractive new clinical application. In this study, the technical groundwork toward performing simultaneous PET/MR breast imaging was developed and systematically evaluated in phantom experiments and breast cancer patient hybrid imaging. Measurements were performed on a state-of-the-art whole-body simultaneous PET/MR system (Biograph mMR, Siemens AG, Erlangen, Germany). The PET signal attenuating effects of a MR-only four-channel radiofrequency (RF) breast coil that is present in the PET field-of-view (FoV) during a simultaneous PET/MR data acquisition has been investigated and quantified. For this purpose, a dedicated PET/MR visible breast phantom featuring four modular inserts with various structures (no insert, MR insert, PET insert, and PET/MR insert) was developed. In addition to a systematic evaluation of MR-only image quality, the following phantom scans were performed using (18)F radio tracer: (1) PET emission scan with only the homogeneous breast phantom; (2) PET emission scan additionally with the RF breast coil in the PET FoV. Attenuation correction (AC) of PET data was performed with CT-based three-dimensional (3D) hardware attenuation maps (μ-maps) of the RF coil and breast phantom. Finally, a simultaneous PET/MR breast imaging was performed in two breast cancer patients. The modular breast phantom allowed for systematic evaluation of various MR, PET, and PET/MR image quality parameters. The RF breast coil provided MR images of good image quality, unaffected by PET imaging. The global attenuation of the RF breast coil on the PET emission data was approximately 11%. This hardware attributed PET signal attenuation was successfully corrected by using an appropriate CT-based 3D μ-map of the RF breast coil. Imaging of two breast cancer patients confirmed the

  15. Comparing Leaf and Root Insertion

    Directory of Open Access Journals (Sweden)

    Jaco Geldenhuys

    2010-07-01

    Full Text Available We consider two ways of inserting a key into a binary search tree: leaf insertion which is the standard method, and root insertion which involves additional rotations. Although the respective cost of constructing leaf and root insertion binary search trees trees, in terms of comparisons, are the same in the average case, we show that in the worst case the construction of a root insertion binary search tree needs approximately 50% of the number of comparisons required by leaf insertion.

  16. Plasmodium vivax antigen discovery based on alpha-helical coiled coil protein motif

    DEFF Research Database (Denmark)

    Céspedes, Nora; Habel, Catherine; Lopez-Perez, Mary

    2014-01-01

    Protein α-helical coiled coil structures that elicit antibody responses, which block critical functions of medically important microorganisms, represent a means for vaccine development. By using bioinformatics algorithms, a total of 50 antigens with α-helical coiled coil motifs orthologous...

  17. Coil design considerations for a high-frequency electromagnetic induction sensing instrument

    Science.gov (United States)

    Sigman, John B.; Barrowes, Benjamin E.; Wang, Yinlin; Bennett, Hollis J.; Simms, Janet E.; Yule, Donald E.; O'Neill, Kevin; Shubitidze, Fridon

    2016-05-01

    Intermediate electrical conductivity (IEC) materials (101S/m carbon fiber (CF), have recently been used to make smart bombs. In addition, homemade improvised explosive devices (IED) can be produced with low conducting materials (10-4S/m low frequency, EMI systems use more wire turns in transmit and receive coils to boost signal-to-noise ratios (SNR), but at higher frequencies, the transmitter current has non-uniform distribution along the coil length. These non-uniform currents change the spatial distribution of the primary magnetic field and disturb axial symmetry and thwart established approaches for inferring subsurface metallic object properties. This paper discusses engineering tradeoffs for sensing with a broader band of frequencies ever used for EMI sensing, with particular focus on coil geometries.

  18. The umbilical coiling index in normal pregnancy

    NARCIS (Netherlands)

    van Diik, C. C.; Franx, A.; de Laat, M. W. M.; Bruinse, H. W.; Visser, G. H. A.; Nikkels, P. G. J.

    2002-01-01

    To provide reference values for the umbilical coiling index in uncomplicated pregnancy. Umbilical cords were collected from livebom singleton infants born after uncomplicated pregnancies. The umbilical coiling index (UCI) was calculated as the number of coils divided by the cord length in

  19. The umbilical coiling index in complicated pregnancy

    NARCIS (Netherlands)

    de Laat, Monique W. M.; van Alderen, Elise D.; Franx, Arie; Visser, Gerard H. A.; Bots, Michiel L.; Nikkels, Peter G. J.

    2007-01-01

    To evaluate umbilical cord coiling in pregnancies with adverse outcome. Umbilical cords and hospital records of 565 consecutive cases with an indication for histological examination of the placenta were studied. The umbilical coiling index (UCI) was determined as the number of complete coils divided

  20. Radiographer involvement with stent insertion to palliate symptomatic dysphagia resulting from neoplastic obstruction

    Energy Technology Data Exchange (ETDEWEB)

    Law, R.L. [Department of Radiology, Frenchay Hospital, Bristol, BS16 1LE (United Kingdom)], E-mail: robert.law@nbt.nhs.uk

    2008-02-15

    Self-expanding metal stent (SEMS) insertion is recognized as an effective palliative treatment for patients with symptomatic dysphagia resulting from inoperable neoplastic occlusion. This paper reviews radiographer involvement in the fluoroscopic deployment of SEMS. One hundred and fifty-eight SEMS were passed in 136 consecutive patients. Radiographers were responsible for the barium swallow and subsequent passage of an oro-gastric wire across the strictured lumen. One hundred and twenty-seven guide wire insertions under fluoroscopic control transgressed the tumour lumen at first attempt. Nine (6.6%) guide wire insertions were unsuccessful at first attempt however two patients (2.7%) had successful second attempts at fluoroscopically guided wire insertion. Five patients went on to have a joint endoscopic/fluoroscopic SEMS procedure, three were successful, two failed. Due to poor health it was decided not to proceed with further intervention with two other patients. With an overall success rate of 96%, a joint radiographer/clinician approach to guide wire insertion and subsequent SEMS deployment using fluoroscopy alone is a safe, time- and cost-effective procedure.

  1. Wire core reactor for NTP

    Science.gov (United States)

    Harty, R. B.

    1991-01-01

    The development of the wire core system for Nuclear Thermal Propulsion (NTP) that took place from 1963 to 1965 is discussed. A wire core consists of a fuel wire with spacer wires. It's an annular flow core having a central control rod. There are actually four of these, with beryllium solid reflectors on both ends and all the way around. Much of the information on the concept is given in viewgraph form. Viewgraphs are presented on design details of the wire core, the engine design, engine weight vs. thrust, a technique used to fabricate the wire fuel element, and axial temperature distribution.

  2. The LHC Insertion Magnets

    CERN Document Server

    Ostojic, R

    2002-01-01

    The Large Hadron Collider comprises eight insertions, four of which are dedicated to the LHC experiments while the others are used for the major collider systems. The various functions of the insertions are fulfilled by a variety of magnet systems, most of them based on the technology of NbTi superconductors cooled by superfluid helium at 1.9 K. A number of stand-alone magnets in the matching sections are operated at 4.5 K, while in the high radiation areas specialised resistive magnets are used. In this paper, we review the concepts underlying the design of the LHC insertions, and report on the design, procurement and testing of the various specialised magnet systems.

  3. Modern wiring practice

    CERN Document Server

    Steward, W E

    2012-01-01

    Continuously in print since 1952, Modern Wiring Practice has now been fully revised to provide an up-to-date source of reference to building services design and installation in the 21st century. This compact and practical guide addresses wiring systems design and electrical installation together in one volume, creating a comprehensive overview of the whole process for contractors and architects, as well as electricians and other installation engineers. Best practice is incorporated throughout, combining theory and practice with clear and accessible explanation, all

  4. Wiring and lighting

    CERN Document Server

    Kitcher, Chris

    2013-01-01

    Wiring and Lighting provides a comprehensive guide to DIY wiring around the home. It sets out the regulations and legal requirements surrounding electrical installation work, giving clear guidelines that will enable the reader to understand what electrical work they are able to carry out, and what the testing and certification requirements are once the work is completed. Topics covered include: Different types of circuits; Types of cables and cable installation under floors and through joists; Isolating, earthing and bonding; Accessory boxes and fixings; Voltage bands; Detailed advice on safe

  5. Electric wiring domestic

    CERN Document Server

    Coker, A J

    1992-01-01

    Electric Wiring: Domestic, Tenth Edition, is a clear and reliable guide to the practical aspects of domestic electric wiring. Intended for electrical contractors, installation engineers, wiremen and students, its aim is to provide essential up to date information on modern methods and materials in a simple, clear, and concise manner. The main changes in this edition are those necessary to bring the work into line with the 16th Edition of the Regulations for Electrical Installations issued by the Institution of Electrical Engineers. The book begins by introducing the basic features of domestic

  6. Coil Migration through a Neuroform 3 Stent during Endovascular Coiling. A Case Report.

    LENUS (Irish Health Repository)

    O'Hare, A

    2009-07-29

    Summary: A 43-year-old woman attended for stent assisted coiling. A Neuroform 30 x 4.5 mm stent had been successfully placed over the left periophthalmic aneurysm. During the coiling the first coil migrated through the crowns in the stent, lodging at the MCA bifurcation. We believe that the coil herniated through the overlying stent due to the carotid siphon curvature and the open cell design. Furthermore the distal markers of the stent impeded coil extraction with a MERCI device.

  7. ISABELLE insertion quadrupoles

    Energy Technology Data Exchange (ETDEWEB)

    Kaugerts, J.; Polk, I.; Sampson, W.; Dahl, P.F.

    1979-01-01

    Beam focussing and control at the beam intersection regions of ISABELLE is accomplished by a number of superconducting insertion quadrupoles. These magnets differ from the standard ISABELLE quadrupoles in various ways. In particular, the requirements of limited space near the intersections and aperture for beam extraction impose constraints on their configuration. To achieve optimum beam focussing and provide tuning flexibility calls for stronger quadrupole trim windings than those in the standard quadrupoles. The magnetic and mechanical design of the insertion quadrupoles and their associated correction and steering windings to accomplish the above tasks is presented.

  8. The Composite Insertion Electrode

    DEFF Research Database (Denmark)

    Atlung, Sven; Zachau-Christiansen, Birgit; West, Keld

    1984-01-01

    . The theoretical basis for such electrodes is discussedand, using a simplified model, equations are derived to describe the distribution of potential and current duringdischarge/charge operation. Under the assumption that the insertion compound particles are small enough to ensureequilibrium, and that the local...... electrode potential depends linearly on the degree of insertion, these equations are solvedto obtain analytical expressions for the discharge curve. It is shown that the parameters which determine the dischargebehavior for a given discharge current are simply related to the effective ionic and electronic...... conductivities, the thicknessof the electrode, the volume fractions, and the slope of the potential curve....

  9. Evaluation of persistent-mode operation in a superconducting MgB2 coil in solid nitrogen

    Science.gov (United States)

    Patel, Dipak; Hossain, Md Shahriar Al; See, Khay Wai; Qiu, Wenbin; Kobayashi, Hiroki; Ma, Zongqing; Kim, Seong Jun; Hong, Jonggi; Park, Jin Yong; Choi, Seyong; Maeda, Minoru; Shahabuddin, Mohammed; Rindfleisch, Matt; Tomsic, Mike; Xue Dou, Shi; Kim, Jung Ho

    2016-04-01

    We report the fabrication of a magnesium diboride (MgB2) coil and evaluate its persistent-mode operation in a system cooled by a cryocooler with solid nitrogen (SN2) as a cooling medium. The main purpose of SN2 was to increase enthalpy of the cold mass. For this work, an in situ processed carbon-doped MgB2 wire was used. The coil was wound on a stainless steel former in a single layer (22 turns), with an inner diameter of 109 mm and height of 20 mm without any insulation. The two ends of the coil were then joined to make a persistent-current switch to obtain the persistent-current mode. After a heat treatment, the whole coil was installed in the SN2 chamber. During operation, the resultant total circuit resistance was estimated to be magnetic resonance imaging application.

  10. Percutaneous Kirschner wire (K-wire) fixation for humerus shaft ...

    African Journals Online (AJOL)

    In the present study, Kirschner wires (K-wire) were used to achieve a closed intramedullary fixation of humeral shaft fractures. The objective of this study was to evaluate the efficacy of intramedullary K-wires for the treatment of humeral shaft fracture in children. Patients and Methods: This prospective study was conducted in ...

  11. Studies of IBL wire bonds operation in a ATLAS-like magnetic field.

    CERN Document Server

    Alvarez Feito, D; Mandelli, B

    2015-01-01

    At the Large Hadron Collider (LHC) experiments, most of silicon detectors use wire bonds to connect front-end chips and sensors to circuit boards for the data and service trans- missions. These wire bonds are operated in strong magnetic field environments and if time varying currents pass through them with frequencies close to their mechanical resonance frequency, strong resonant oscillations may occur. Under certain conditions, this effect can lead to fatigue stress and eventually breakage of wire bonds. During the first LHC Long Shutdown, the ATLAS Pixel Detector has been upgraded with the addition of a fourth innermost layer, the Insertable B-Layer (IBL), which has more than 50000 wire bonds operated in the ATLAS 2 T magnetic field. The results of systematic studies of operating wire bonds under IBL-like conditions are presented. Two different solutions have been investigated to minimize the oscillation amplitude of wire bonds.

  12. An unusual case of intrarenal coiled and ruptured guidewire.

    Science.gov (United States)

    Manassero, Francesca; Ortori, Simona; Gabellieri, Cristina; Gabelloni, Michela; Selli, Cesare

    2015-03-31

    To the best of our knowledge there are only 3 reports of fractured guidewires inside the pelvicalyceal system, successfully removed with endourology techniques, and this is the first one presenting a tightly coiled intraparenchymal section. A 59-year-old woman was hospitalized for surgical treatment of a right kidney of reduced size. Past history revealed pyelolithotomy for a staghorn stone 14 months earlier at another Institution with subsequent ureteral obstruction, one failed attempt at ureteral double-J catheter insertion and one failed attempt at percutaneous nephrostomy placement 5 months postoperatively. Another nephrostomy was placed, but left indwelling briefly. CT scan demonstrated a small-size kidney with residual stone fragments and presence of a "device" in the lower pole. The tapered distal extremity of an hydrophilic guidewire, with a tightly coiled central section wedged in the renal tissue was found inside the nephrectomy specimen. While the Radiologist who read the CT scan hypothesized that the "device" was a fragment of double-J ureteral stent or nephrostomy catheter, it consisted of the hydrophilic extremity of a guidewire, broken during a previous attempt at nephrostomy placement. Perirenal fibrosis and inappropriate angle between the needle and the lower calyx are the likely causes of guidewire coiling during its advancement and subsequent rupture during withdrawal. Urologists must be aware that, although percutaneous nephrostomy has a very high technical success rate, unusual complications like guidewire fracture may occur, and that modern imaging techniques can provide an accurate picture of this condition.

  13. Wiring for space applications program

    Science.gov (United States)

    Hammoud, Ahmad

    1994-01-01

    The insulation testing and analysis consists of: identifying and prioritizing NASA wiring requirements; selecting candidate wiring constructions; developing test matrix and formulating test program; managing, coordinating, and conducting tests; and analyzing and documenting data, establishing guidelines and recommendations.

  14. Insertion in Persian

    Science.gov (United States)

    Kambuziya, Aliyeh Kord-e Zafaranlu; Dehghan, Masoud

    2011-01-01

    This paper investigates epenthesis process in Persian to catch some results in relating to vowel and consonant insertion in Persian lexicon. This survey has a close relationship to the description of epenthetic consonants and the conditions in which these consonants are used. Since no word in Persian may begin with a vowel, so that hiatus can't be…

  15. Inserting the CMS solenoid

    CERN Multimedia

    Maximilien Brice

    2005-01-01

    The huge superconducting solenoid for CMS is inserted into the cryostat barrel. CMS uses the world's largest thin solenoid, in terms of energy stored, and is 12 m long, with a diameter of 6 m and weighing 220 tonnes. When turned on the magnet will produce a field strength of 4 T using superconducting niobium-titanium material at 4.5 K.

  16. Pixel detector insertion

    CERN Multimedia

    CMS

    2015-01-01

    Insertion of the Pixel Tracker, the 66-million-channel device used to pinpoint the vertex of each colliding proton pair, located at the heart of the detector. The geometry of CMS is a cylinder lying on its side (22 meters long and 15 meters high in dia

  17. Debate: Wired versus Wireless.

    Science.gov (United States)

    Meeks, Glenn; Nair, Prakash

    2000-01-01

    Debates the issue of investing in wiring schools for desktop computer networks versus using laptops and wireless networks. Included are cost considerations and the value of technology for learning. Suggestions include using wireless networks for existing schools, hardwiring computers for new construction, and not using computers for elementary…

  18. Wired vs. Wireless.

    Science.gov (United States)

    Fielding, Randall

    2000-01-01

    Presents a debate on which technology will be in tomorrow's classrooms and the pros and cons of wiring classrooms and using a wireless network. Concluding comments address the likelihood, and desirability, of placing computers throughout the entire educational process and what types of computers and capabilities are needed. (GR)

  19. Wired to freedom

    DEFF Research Database (Denmark)

    Jepsen, Kim Sune Karrasch; Bertilsson, Margareta

    2017-01-01

    dimension of life science through a notion of public politics adopted from the political theory of John Dewey. We show how cochlear implantation engages different social imaginaries on the collective and individual levels and we suggest that users share an imaginary of being “wired to freedom” that involves...

  20. Gaseous wire detectors

    Energy Technology Data Exchange (ETDEWEB)

    Va' vra, J.

    1997-08-01

    This article represents a series of three lectures describing topics needed to understand the design of typical gaseous wire detectors used in large high energy physics experiments; including the electrostatic design, drift of electrons in the electric and magnetic field, the avalanche, signal creation, limits on the position accuracy as well as some problems one encounters in practical operations.

  1. 3D Wire 2015

    DEFF Research Database (Denmark)

    Jordi, Moréton; F, Escribano; J. L., Farias

    This document is a general report on the implementation of gamification in 3D Wire 2015 event. As the second gamification experience in this event, we have delved deeply in the previous objectives (attracting public areas less frequented exhibition in previous years and enhance networking) and have...

  2. Coiled transmission line pulse generators

    Science.gov (United States)

    McDonald, Kenneth Fox

    2010-11-09

    Methods and apparatus are provided for fabricating and constructing solid dielectric "Coiled Transmission Line" pulse generators in radial or axial coiled geometries. The pour and cure fabrication process enables a wide variety of geometries and form factors. The volume between the conductors is filled with liquid blends of monomers, polymers, oligomers, and/or cross-linkers and dielectric powders; and then cured to form high field strength and high dielectric constant solid dielectric transmission lines that intrinsically produce ideal rectangular high voltage pulses when charged and switched into matched impedance loads. Voltage levels may be increased by Marx and/or Blumlein principles incorporating spark gap or, preferentially, solid state switches (such as optically triggered thyristors) which produce reliable, high repetition rate operation. Moreover, these Marxed pulse generators can be DC charged and do not require additional pulse forming circuitry, pulse forming lines, transformers, or an a high voltage spark gap output switch. The apparatus accommodates a wide range of voltages, impedances, pulse durations, pulse repetition rates, and duty cycles. The resulting mobile or flight platform friendly cylindrical geometric configuration is much more compact, light-weight, and robust than conventional linear geometries, or pulse generators constructed from conventional components. Installing additional circuitry may accommodate optional pulse shape improvements. The Coiled Transmission Lines can also be connected in parallel to decrease the impedance, or in series to increase the pulse length.

  3. Practical wiring in SI units

    CERN Document Server

    Miller, Henry A

    2013-01-01

    Practical Wiring, Volume 1 is a 13-chapter book that first describes some of the common hand tools used in connection with sheathed wiring. Subsequent chapters discuss the safety in wiring, cables, conductor terminations, insulating sheathed wiring, conductor sizes, and consumer's control equipments. Other chapters center on socket outlets, plugs, lighting subcircuits, lighting accessories, bells, and primary and secondary cells. This book will be very valuable to students involved in this field of interest.

  4. Wire EDM for Refractory Materials

    Science.gov (United States)

    Zellars, G. R.; Harris, F. E.; Lowell, C. E.; Pollman, W. M.; Rys, V. J.; Wills, R. J.

    1982-01-01

    In an attempt to reduce fabrication time and costs, Wire Electrical Discharge Machine (Wire EDM) method was investigated as tool for fabricating matched blade roots and disk slots. Eight high-strength nickel-base superalloys were used. Computer-controlled Wire EDM technique provided high quality surfaces with excellent dimensional tolerances. Wire EDM method offers potential for substantial reductions in fabrication costs for "hard to machine" alloys and electrically conductive materials in specific high-precision applications.

  5. First qualification of ITER Toroidal Field Coil conductor jacketing

    Energy Technology Data Exchange (ETDEWEB)

    Hamada, Kazuya, E-mail: hamada.kazuya@jaea.go.jp [Japan Atomic Energy Agency (Japan); Takahashi, Yoshikazu; Isono, Takaaki; Nunoya, Yoshihiko; Matsui, Kunihiro; Kawano, Katsumi; Oshikiri, Masayuki; Tsutsumi, Fumiaki; Koizumi, Norikiyo; Nakajima, Hideo; Okuno, Kiyoshi [Japan Atomic Energy Agency (Japan); Matsuda, Hidemitsu; Yano, Yoshitaka [Nippon Steel Engineering Co. Ltd (Japan); Devred, Arnauld; Bessette, Denis [ITER Organization (France)

    2011-10-15

    The Japan Atomic Energy Agency (JAEA) has the responsibility to procure 25% of the ITER Toroidal Field Coil conductors as the Japanese Domestic Agency (JADA) in the ITER project. The TF conductor is a circular shaped, cable-in-conduit conductor, composed of a cable and a stainless steel conduit (jacket). The outer diameter and maximum length of the TF conductor are 43.7 mm and 760 m, respectively. JAEA started to produce strand, cables and jacket sections and to construct a conductor manufacturing (jacketing) facility in 2008. Following preparation in December 2009 of the jacketing facility, the dummy cable, the jacket sections and fabrication procedures, such as welding, cable insertion, compaction and spooling, JAEA manufactured a 760 m long Cu dummy conductor for process qualification. Into the 760 m long Cu dummy conductor jacketing, JAEA successfully inserted the cable with a maximum force of 32 kN. The outer diameter of the cross section of the spooled conductor was 43.7 {+-} 0.15 mm, which complies with the ITER target requirement of 43.7 {+-} 0.3 mm. Following qualification of all manufacturing processes, JAEA has started to fabricate superconducting conductors for the TF coils.

  6. Introduction of CORC® wires: highly flexible, round high-temperature superconducting wires for magnet and power transmission applications

    Science.gov (United States)

    Weiss, Jeremy D.; Mulder, Tim; ten Kate, Herman J.; van der Laan, Danko C.

    2017-01-01

    Conductor on Round Core (CORC®) technology has achieved a long sought-after benchmark by enabling the production of round, multifilament, (RE)Ba2Ca3O7-x coated conductors with practical current densities for use in magnets and power applications. Recent progress, including the demonstration of engineering current density beyond 300 Amm-2 at 4.2 K and 20 T, indicates that CORC® cables are a viable conductor for next generation high field magnets. Tapes with 30 μm substrate thickness and tape widths down to 2 mm have improved the capabilities of CORC® technology by allowing the production of CORC® wires as thin as 3 mm in diameter with the potential to enhance the engineering current density further. An important benefit of the thin CORC® wires is their improved flexibility compared to thicker (7-8 mm diameter) CORC® cables. Critical current measurements were carried out on tapes extracted from CORC® wires made using 2 and 3 mm wide tape after bending the wires to various diameters from 10 to 3.5 cm. These thin wires are highly flexible and retain close to 90% of their original critical current even after bending to a diameter of 3.5 cm. A small 5-turn solenoid was constructed and measured as a function of applied magnetic field, exhibiting an engineering current density of 233 Amm-2 at 4.2 K and 10 T. CORC® wires thus form an attractive solution for applications between 4.2 and 77 K, including high-field magnets that require high current densities with small bending diameters, benefiting from a ready-to-use form (similar to NbTi and contrary to Nb3Sn wires) that does not require additional processing following coil construction.

  7. Percutaneous cerclage wiring, does it disrupt femoral blood supply? A cadaveric injection study.

    Science.gov (United States)

    Apivatthakakul, T; Phaliphot, J; Leuvitoonvechkit, S

    2013-02-01

    A percutaneous cerclage wiring technique has been developed to reduce iatrogenic soft tissue and vascular disruption associated with classic cerclage fixation. The purpose of this study was to evaluate the extent of femoral vascular disruption resulting iatrogenically from the application of two percutaneous cerclage wire loops. Pairs of cerlage wire loops were percutaneously inserted on 18 fresh cadaveric femurs. The position of the wire loops varied. The wire loops were either inserted 10 and 15cm, 10 and 20cm, or 15 and 20cm distal to the tip of the greater trochanter. Each study group had 6 cadavers. Contralateral femurs without cerclage wiring were used as controls. Liquid contrast-gelatin was injected into the common femoral artery. Using axial and 3D CT scan images the superficial femoral artery (SFA), deep femoral artery (DFA), perforating arteries and their anastomotic patterns as well as endosteal perfusion were identified and their patency was graded. Percutaneous cerclage wiring did not disrupt femoral endosteal blood supply and maintained the integrity of all of the superficial femoral arteries. Four specimens demonstrated maintenance of all 4 perforators, 11 showed disruption of 1 perforator, and 3 showed disruption of 2 perforators. One deep femoral artery was disrupted after its first perforator branched off; however, perfusion was maintained by fill from an alternative anastamosis. There was no significant difference between disruption of deep femoral arteries and perforating arteries (P=1.000), location of wiring (P=0.905) or spacing between wire loops (P=1.000). Percutaneous cerclage wiring resulted in minimal disruption of the femoral blood supply. When partial disruption occurred the SFA, DFA, and their associated perforators compensated to maintain femoral perfusion through their anastomoses. The location of the cerclage wire and the distance between the wire loops in the proximal femur showed no significant difference in the rate of

  8. Growth Factor Identity Is Encoded by Discrete Coiled-Coil Rotamers in the EGFR Juxtamembrane Region.

    Science.gov (United States)

    Doerner, Amy; Scheck, Rebecca; Schepartz, Alanna

    2015-06-18

    Binding of transforming growth factor α (TGF-α) to the epidermal growth factor receptor (EGFR) extracellular domain is encoded through the formation of a unique antiparallel coiled coil within the juxtamembrane segment. This new coiled coil is an "inside-out" version of the coiled coil formed in the presence of epidermal growth factor (EGF). A third, intermediary coiled-coil interface is formed in the juxtamembrane region when EGFR is stimulated with betacellulin. The seven growth factors that activate EGFR in mammalian systems (EGF, TGF-α, epigen, epiregulin, betacellulin, heparin-binding EGF, and amphiregulin) fall into distinct categories in which the structure of the coiled coil induced within the juxtamembrane region correlates with cell state. The observation that coiled-coil state tracks with the downstream signaling profiles for each ligand provides evidence for growth factor functional selectivity by EGFR. Encoding growth factor identity in alternative coiled-coil rotamers provides a simple and elegant method for communicating chemical information across the plasma membrane. Copyright © 2015 Elsevier Ltd. All rights reserved.

  9. A 16-channel receive, forced current excitation dual-transmit coil for breast imaging at 7T.

    Directory of Open Access Journals (Sweden)

    Samantha By

    Full Text Available To enable high spatial and temporal breast imaging resolution via combined use of high field MRI, array coils, and forced current excitation (FCE multi channel transmit.A unilateral 16-channel receive array insert was designed for use in a transmit volume coil optimized for quadrature operation with dual-transmit RF shimming at 7 T. Signal-to-noise ratio (SNR maps, g-factor maps, and high spatial and temporal resolution in vivo images were acquired to demonstrate the utility of the coil architecture.The dual-transmit FCE coil provided homogeneous excitation and the array provided an increase in average SNR of 3.3 times (max 10.8, min 1.5 compared to the volume coil in transmit/receive mode. High resolution accelerated in vivo breast imaging demonstrated the ability to achieve isotropic spatial resolution of 0.5 mm within clinically relevant 90 s scan times, as well as the ability to perform 1.0 mm isotropic resolution imaging, 7 s per dynamics, with the use of bidirectional SENSE acceleration of up to R = 9.The FCE design of the transmit coil easily accommodates the addition of a sixteen channel array coil. The improved spatial and temporal resolution provided by the high-field array coil with FCE dual-channel transmit will ultimately be beneficial in lesion detection and characterization.

  10. Momentum-weighted conjugate gradient descent algorithm for gradient coil optimization.

    Science.gov (United States)

    Lu, Hanbing; Jesmanowicz, Andrzej; Li, Shi-Jiang; Hyde, James S

    2004-01-01

    MRI gradient coil design is a type of nonlinear constrained optimization. A practical problem in transverse gradient coil design using the conjugate gradient descent (CGD) method is that wire elements move at different rates along orthogonal directions (r, phi, z), and tend to cross, breaking the constraints. A momentum-weighted conjugate gradient descent (MW-CGD) method is presented to overcome this problem. This method takes advantage of the efficiency of the CGD method combined with momentum weighting, which is also an intrinsic property of the Levenberg-Marquardt algorithm, to adjust step sizes along the three orthogonal directions. A water-cooled, 12.8 cm inner diameter, three axis torque-balanced gradient coil for rat imaging was developed based on this method, with an efficiency of 2.13, 2.08, and 4.12 mT.m(-1).A(-1) along X, Y, and Z, respectively. Experimental data demonstrate that this method can improve efficiency by 40% and field uniformity by 27%. This method has also been applied to the design of a gradient coil for the human brain, employing remote current return paths. The benefits of this design include improved gradient field uniformity and efficiency, with a shorter length than gradient coil designs using coaxial return paths. Copyright 2003 Wiley-Liss, Inc.

  11. Understanding Irreversible Degradation of Nb3Sn Wires with Fundamental Fracture Mechanics

    Energy Technology Data Exchange (ETDEWEB)

    Zhai, Yuhu [PPPL; Calzolaio, Ciro [Univ of Geneva; Senatore, Carmine [Univ of Geneva

    2014-08-01

    Irreversible performance degradation of advanced Nb3Sn superconducting wires subjected to transverse or axial mechanical loading is a critical issue for the design of large-scale fusion and accelerator magnets such as ITER and LHC. Recent SULTAN tests indicate that most cable-in-conduit conductors for ITER coils made of Nb3Sn wires processed by various fabrication techniques show similar performance degradation under cyclic loading. The irreversible degradation due to filament fracture and local strain accumulation in Nb3Sn wires cannot be described by the existing strand scaling law. Fracture mechanic modeling combined with X-ray diffraction imaging of filament micro-crack formation inside the wires under mechanical loading may reveal exciting insights to the wire degradation mechanisms. We apply fundamental fracture mechanics with a singularity approach to study influence of wire filament microstructure of initial void size and distribution to local stress concentration and potential crack propagation. We report impact of the scale and density of the void structure on stress concentration in the composite wire materials for crack initiation. These initial defects result in an irreversible degradation of the critical current beyond certain applied stress. We also discuss options to minimize stress concentration in the design of the material microstructure for enhanced wire performance for future applications.

  12. PET Performance Evaluation of an MR-Compatible PET Insert

    Science.gov (United States)

    Wu, Yibao; Catana, Ciprian; Farrell, Richard; Dokhale, Purushottam A.; Shah, Kanai S.; Qi, Jinyi; Cherry, Simon R.

    2009-06-01

    A magnetic resonance (MR) compatible positron emission tomography (PET) insert has been developed in our laboratory for simultaneous small animal PET/MR imaging. This system is based on lutetium oxyorthosilicate (LSO) scintillator arrays with position-sensitive avalanche photodiode (PSAPD) photodetectors. The PET performance of this insert has been measured. The average reconstructed image spatial resolution was 1.51 mm. The sensitivity at the center of the field of view (CFOV) was 0.35%, which is comparable to the simulation predictions of 0.40%. The average photopeak energy resolution was 25%. The scatter fraction inside the MRI scanner with a line source was 12% (with a mouse-sized phantom and standard 35 mm Bruker 1 H RF coil), 7% (with RF coil only) and 5% (without phantom or RF coil) for an energy window of 350-650 keV. The front-end electronics had a dead time of 390 ns, and a trigger extension dead time of 7.32 mus that degraded counting rate performance for injected doses above 0.75 mCi (28 MBq). The peak noise-equivalent count rate (NECR) of 1.27 kcps was achieved at 290 muCi (10.7 MBq). The system showed good imaging performance inside a 7-T animal MRI system; however improvements in data acquisition electronics and reduction of the coincidence timing window are needed to realize improved NECR performance.

  13. Magnetic characterization of the nickel layer protecting the copper wires in harsh applications

    Directory of Open Access Journals (Sweden)

    Roger Daniel

    2017-06-01

    Full Text Available High Temperature (HT° motor coils open new perspectives for extending the applications of electrical motors or generators to very harsh environments or for designing very high power density machines working with high internal temperature gradients. Over a temperature of 300°C, the classic enameled wire cannot work permanently, the turn-to-turn insulation must be inorganic and made with high temperature textiles or vitro-ceramic compounds. For both cases, a diffusion barrier must protect the copper wire against oxidation. The usual solution consists of adding a nickel layer that yields an excellent chemical protection. Unfortunately, the nickel has ferromagnetic properties that change a lot the skin effect in the HT wire at high frequencies. For many applications such as aeronautics, electrical machines are always associated with PWM inverters for their control. The windings must resist to high voltage short spikes caused by the fast fronted pulses imposed by the feeding inverter. The nickel protection layer of the HT° inorganic wire has a large influence on the high frequency behavior of coils and, consequently, on the magnitude of the voltage spikes. A good knowledge of the non-linear magnetic characteristics of this nickel layer is helpful for designing reliable HT inorganic coils. The paper presents a method able to characterize non-linear electromagnetic properties of this nickel layer up to 500°C.

  14. Application of the Wire Bonding Technology to a Flexible Neural Probe

    Science.gov (United States)

    Shimizu, Koichi; Nakanishi, Motofumi; Makikawa, Masaaki; Asajima, Syuzo; Konishi, Satoshi

    This paper proposes a novel neural probe using flexible metal wire for wire bonding on LSI chip. Wire bonding technology can provide a number of flexible wire arrays. The proposed neural probe is used for a nerve interface for functional electric stimulation (FES) technology which assists the paralysis of living body function by a spinal cord injury. The flexibility of probe will provide low invasive and safe neural interfaces for the nerve tissue from a long term view. We employ a combination of wire bonding and laser machining for the fabrication of aligned flexible probes. Aligned bonded flexible metal wires on electrodes are converted to probe arrays by cutting the bridge between electrodes. Typical dimension of a bonding wire is several tens μm in diameter and is suitable for neural probe to be inserted into nerve bundles. Needle shape is formed by electro-polishing of cut edge. Proposed method can be benefited by advantages of wire bonding as the widespread technology in electronics industry. Developed flexible neural probe based on the proposed technology is estimated as a nerve interface by inserting to a sciatic nerve of a rat.

  15. Design Challenges for a Wide-Aperture Insertion Quadrupole Magnet

    CERN Document Server

    Russenschuck, S; Perez, J C; Ramos, D; Fessia, P; Karppinen, M; Kirby, G; Sahner, T; Schwerg, N

    2011-01-01

    The design and development of a superconducting (Nb-Ti) quadrupole with 120 mm aperture, for an upgrade of the LHC insertion region, faces challenges arising from the LHC beam optics requirements and the heat-deposition. The first triggered extensive studies of coil alternatives with four and six coil-blocks in view of field quality and operation margins. The latter requires more porous insulation schemes for both the cables and the ground-plane. This in turn necessitates extensive heatpropagation and quench-velocity studies, as well as more efficient quench heaters. The engineering design of the magnet includes innovative features such as self-locking collars, which will enable the collaring to be performed with the coils on a horizontal assembly bench, a spring-loaded and collapsible assembly mandrel, tuning-shims for field quality, porous collaring-shoes, and coil end-spacer design based on differential geometry methods. The project also initiated code extensions in the quench-simulation and CAD/CAM module...

  16. Balloon-expandable stenting with and without coiling for wide-neck and complex aneurysms.

    Science.gov (United States)

    Zenteno, Marco; Modenesi Freitas, José Maria; Aburto-Murrieta, Yolanda; Koppe, Gelson; Machado, Elcio; Lee, Angel

    2006-12-01

    Wide-necked, saccular, dissecting, and fusiform intracranial aneurysms are poor coil retainers. Retention can be improved by parent-artery stenting across the aneurysm. We used a balloon-expandable stent and delivery system, intending to treat 38 aneurysms in 36 patients. Stents could not be advanced across the neck of 2 aneurysms near the ophthalmic artery origin. These cases were managed by temporary balloon remodeling and coiling. Stenting alone was done for 15 aneurysms, including 7 in vertebral artery V4 segments. Stenting with immediate or delayed coiling was done in 21 aneurysms. Stenting alone caused immediate and complete obliteration of 1 treated aneurysm (7%), subtotal obliteration in 13 treated (86%) aneurysms, and was associated with 1 failure. Stenting and coiling yielded a significantly better 57% complete obliteration rate, 43% subtotal obliteration, and no failures. There were 5 complications: 1 wire perforation, 2 cavernous-carotid-sinus fistulae, and 2 partial in-stent thromboses. All were controlled or cleared with no long-term sequelae or deaths. Contrast imaging at 1 to 12 months was available for 30 patients (13 stent-only, 17 stent-plus-coiling), demonstrating complete obliteration in 25 (83%) and subtotal obliteration in 5. A total of 7 stent-only aneurysms (4 V4s) were completely obliterated, and 3 (all V4s) were > or = 90% obliterated. Stenting and coiling through the wall of the stent resulted in 88% (15/17) complete obliteration when imaged 1 to 12 months after treatment. Stenting alone effectively closed off V4-segment wide-necked aneurysms but was inferior to stenting and coiling in less mobile vessels.

  17. Obelix Wire Chamber

    CERN Multimedia

    1986-01-01

    Two wire chambers made originally for the R807 Experiment at CERN's Intersecting Storage Rings. In 1986 they were used for the PS 201 experiment (Obelix Experiment) at LEAR, the Low Energy Antiproton Ring. The group of researchers from Turin, using the chambers at that time, changed the acquisition system using for the first time 8 bit (10 bit non linear) analog to digital conversion for incoming signals from the chambers. The acquisition system was controlled by 54 CPU and 80 digital signal processors. The power required for all the electronics was 40 kW. For the period, this system was one of the most powerful on-line apparatus in the world. The Obelix Experiment was closed in 1996. To find more about how a wire chamber works, see the description for object CERN-OBJ-DE-038.

  18. Injury to neurovascular structures with insertion of traction pins around the knee.

    Science.gov (United States)

    Lowe, Jason A; Rister, Jamie; Eastman, Jonathan; Freind, Jonathan

    2015-10-01

    Identify risk to neurovascular structures around the knee with placement of skeletal traction pins. Kirchner wires were inserted into cadaveric limbs followed by layer dissecting of each leg. Correlations between weight, height, BMI, and distance were determined after calculating the average distance with deviation between each anatomic structure and the Kirschner wire. Insertion of traction pins around the knee did not result in injury to neurovascular structures. Both weight and BMI positively correlated with distance between implants and neurovascular structure. Data collected suggests similar trends for all other anatomic structures.

  19. Command Wire Sensor Measurements

    Science.gov (United States)

    2012-09-01

    NPS anechoic chamber is located in Spanagel Hall, Room 604. Although the chamber was built for instruction purposes only, it can be used for research...thesis is to investigate the wire scattering behavior and clutter characteristics through measurements performed in the NPS anechoic chamber. The...research has successfully resolved the various multipath components within the anechoic chamber. The transmit-receive coupling between the antennas was

  20. DEVELOPMENT OF COILED TUBING STRESS ANALYSIS

    Directory of Open Access Journals (Sweden)

    Davorin Matanović

    1998-12-01

    Full Text Available The use of coiled tubing is increasing rapidly with drilling of horizontal wells. To satisfy all requirements (larger mechanical stresses, larger fluid capacities the production of larger sizes and better material qualities was developed. Stresses due to axial forces and pressures that coiled tubing is subjected are close to its performance limits. So it is really important to know and understand the behaviour of coiled tubing to avoid its break, burst or collapse in the well.

  1. 76 FR 68407 - Galvanized Steel Wire From the People's Republic of China: Preliminary Determination of Sales at...

    Science.gov (United States)

    2011-11-04

    ... galvanized steel wire which is a cold-drawn carbon quality steel product in coils, of solid, circular cross... surrogate country, see ``Surrogate Country'' section below. \\20\\ See ``Memorandum from Carole Showers... Africa, Thailand, and Ukraine, have been previously found by the Department to have benefitted from...

  2. Transport vesicle tethering at the trans Golgi network: coiled coil proteins in action

    Directory of Open Access Journals (Sweden)

    Pak-yan Patricia Cheung

    2016-03-01

    Full Text Available The Golgi complex is decorated with so-called Golgin proteins that share a common feature: a large proportion of their amino acid sequences are predicted to form coiled-coil structures. The possible presence of extensive coiled coils implies that these proteins are highly elongated molecules that can extend a significant distance from the Golgi surface. This property would help them to capture or trap inbound transport vesicles and to tether Golgi mini-stacks together. This review will summarize our current understanding of coiled coil tethers that are needed for the receipt of transport vesicles at the trans Golgi network. How do long tethering proteins actually catch vesicles? Golgi-associated, coiled coil tethers contain numerous binding sites for small GTPases, SNARE proteins, and vesicle coat proteins. How are these interactions coordinated and are any or all of them important for the tethering process? Progress towards understanding these questions and remaining, unresolved mysteries will be discussed.

  3. Helical axis stellarator with noninterlocking planar coils

    Science.gov (United States)

    Reiman, Allan; Boozer, Allen H.

    1987-01-01

    A helical axis stellarator using only noninterlocking planar, non-circular coils, generates magnetic fields having a magnetic well and large rotational transform with resultant large equilibrium beta.

  4. CoTEx - Coil tests for the neutron lifetime experiment PENeLOPE

    Energy Technology Data Exchange (ETDEWEB)

    Gaisbauer, Dominic [Technische Universitaet Muenchen, Physikdepartment E18 (Germany); Collaboration: PENeLOPE-Collaboration

    2014-07-01

    PENeLOPE is an experiment with ultra-cold neutrons (UCN) for determining their lifetime in a magneto-gravitational trap with special designed superconducting coils developed at Technische Universitaet Muenchen. It is designed to have a precision of up to 'pm 0.1s. Due to their unique characteristics all coils for the trap have to be trained and tested in a preliminary experiment called CoTEx before they can be inserted into PENeLOPE. The poster highlights the results of the first welded coil stack delivered in December 2013. A short overview of CoTEx in general and the slow control and quench detection of CoTEx are also presented.

  5. Room Temperature Magnetic Determination of the Current Center Line for the ITER TF Coils

    CERN Document Server

    Lerch, Philippe; Buzio, Marco; Negrazus, Marco; Baynham, Elwyn; Sanfilippo, Stephane; Foussat, Arnaud

    2014-01-01

    The ITER tokamak includes 18 superconducting D-shaped toroidal field (IT) coils. Unavoidable shape deformations as well as assembly errors will lead to field errors, which can be modeled with the knowledge of the current center line (CCL). Accurate survey during the entire manufacturing and assembly process, including transfer of survey points, is complex. In order to increase the level of confidence, a room temperature magnetic measurement of the CCL on assembled and closed winding packs is foreseen, prior to insertion into their cold case. In this contribution, we discuss the principle of the CCL determination and present a low frequency ac measurement system under development at PSI, within an ITER framework contract. The largest current allowed to flow in the TF coil at room temperature and the precision requirements for the determination of the CCL loci of the coil are hard boundaries. Eddy currents in the radial plates, the winding pack enclosures, and possibly from iron in the reinforced concrete floor...

  6. The MQXA quadrupoles for the LHC low-beta insertions

    Energy Technology Data Exchange (ETDEWEB)

    Ajima, Y. [High Energy Accelerator Research Organization (KEK), Tsukuba, 305-0801 (Japan); Higashi, N. [High Energy Accelerator Research Organization (KEK), Tsukuba, 305-0801 (Japan); Iida, M. [High Energy Accelerator Research Organization (KEK), Tsukuba, 305-0801 (Japan); Kimura, N. [High Energy Accelerator Research Organization (KEK), Tsukuba, 305-0801 (Japan); Nakamoto, T. [High Energy Accelerator Research Organization (KEK), Tsukuba, 305-0801 (Japan); Ogitsu, T. [High Energy Accelerator Research Organization (KEK), Tsukuba, 305-0801 (Japan); Ohhata, H. [High Energy Accelerator Research Organization (KEK), Tsukuba, 305-0801 (Japan); Ohuchi, N. [High Energy Accelerator Research Organization (KEK), Tsukuba, 305-0801 (Japan); Shintomi, T. [High Energy Accelerator Research Organization (KEK), Tsukuba, 305-0801 (Japan); Sugawara, S. [High Energy Accelerator Research Organization (KEK), Tsukuba, 305-0801 (Japan); Sugita, K. [High Energy Accelerator Research Organization (KEK), Tsukuba, 305-0801 (Japan); Tanaka, K. [High Energy Accelerator Research Organization (KEK), Tsukuba, 305-0801 (Japan); Taylor, T. [High Energy Accelerator Research Organization (KEK), Tsukuba, 305-0801 (Japan); Terashima, A. [High Energy Accelerator Research Organization (KEK), Tsukuba, 305-0801 (Japan); Tsuchiya, K. [High Energy Accelerator Research Organization (KEK), Tsukuba, 305-0801 (Japan)]. E-mail: kiyosumi.tsuchiya@kek.jp; Yamamoto, A. [High Energy Accelerator Research Organization (KEK), Tsukuba, 305-0801 (Japan)

    2005-09-21

    High-performance superconducting quadrupole magnets, MQXA, for the LHC low-beta insertions have been designed, manufactured in series and tested. The design field gradient of the quadrupole, which has a coil aperture of diameter 70 mm, was 240 T/m at 1.9 K; its effective length is 6.37 m, and it is required to operate reliably at up to 215 T/m when subjected to radiation heat deposit in the coils of up to 5 W/m. The series of 20 magnets has been produced in industry, and tested at KEK. The magnet design is explained, and the construction and performance of the series units, in terms of training, field quality and geometry, are presented.

  7. Dual wire welding torch and method

    Science.gov (United States)

    Diez, Fernando Martinez; Stump, Kevin S.; Ludewig, Howard W.; Kilty, Alan L.; Robinson, Matthew M.; Egland, Keith M.

    2009-04-28

    A welding torch includes a nozzle with a first welding wire guide configured to orient a first welding wire in a first welding wire orientation, and a second welding wire guide configured to orient a second welding wire in a second welding wire orientation that is non-coplanar and divergent with respect to the first welding wire orientation. A method of welding includes moving a welding torch with respect to a workpiece joint to be welded. During moving the welding torch, a first welding wire is fed through a first welding wire guide defining a first welding wire orientation and a second welding wire is fed through a second welding wire guide defining a second welding wire orientation that is divergent and non-coplanar with respect to the first welding wire orientation.

  8. Superconducting Coil of Po Dipole

    CERN Multimedia

    1983-01-01

    The Po superconducting dipole was built as a prototype beam transport magnet for the SPS extracted proton beam P0. Its main features were: coil aperture 72 mm, length 5 m, room-temperature yoke, NbTi cable conductor impregnated with solder, nominal field 4.2 T at 4.7 K (87% of critical field). It reached its nominal field without any quench.After this successful test up to its nominal field of 4.2 T, the power was not raised to reach a quench. The magnet was not installed in a beam and had no other further use. Nevertheless its construction provided knowledges and experience which became useful in the design and construction of the LHC magnets. The photo shows a detail of the inner layer winding before superposing the outer layer to form the complete coil of a pole. Worth noticing is the interleaved glass-epoxy sheet (white) with grooved channels for the flow of cooling helium. See also 8211532X.

  9. Compact stellarators with modular coils

    Science.gov (United States)

    Garabedian, P. R.

    2000-01-01

    Compact stellarator designs with modular coils and only two or three field periods are now available; these designs have both good stability and quasiaxial symmetry providing adequate transport for a magnetic fusion reactor. If the bootstrap current assumes theoretically predicted values a three field period configuration is optimal, but if that net current turns out to be lower, a device with two periods and just 12 modular coils might be better. There are also attractive designs with quasihelical symmetry and four or five periods whose properties depend less on the bootstrap current. Good performance requires that there be a satisfactory magnetic well in the vacuum field, which is a property lacking in a stellarator-tokamak hybrid that has been proposed for a proof of principle experiment. In this paper, we present an analysis of stability for these configurations that is based on a mountain pass theorem asserting that, if two solutions of the problem of magnetohydrodynamic equilibrium can be found, then there has to be an unstable solution. We compare results of our theory of equilibrium, stability, and transport with recently announced measurements from the large LHD experiment in Japan. PMID:10899993

  10. Redefining Zone II: Anatomy of the Flexor Digitorum Superficialis Insertion.

    Science.gov (United States)

    Nicholson, Luke T; Hill, Jeffrey R; McKnight, Braden; Heckmann, Nathanael; Stevanovic, Milan; Ghiassi, Alidad

    2017-10-01

    Flexor zone II is defined as the region spanning the proximal aspect of the A1 pulley to the insertion of the flexor digitorum superficialis (FDS) tendon. Descriptions of the FDS insertion are inconsistent in the literature, but zones of injury are frequently determined with reference to superficial landmarks. The purpose of this study was to describe the footprint of the FDS insertion and define its relationship to the proximal interphalangeal (PIP) skin crease. The FDS insertion on the index, middle, ring, and small fingers was dissected in 6 matched pairs of fresh-frozen cadaveric hands. A Kirschner wire was used to mark the level of the PIP skin crease on bone before measurements of the FDS footprint and its position relative to the PIP skin crease were made using digital calipers. The radial and ulnar FDS slips inserted a mean distance of 3.22 mm from the distal aspect of the PIP skin crease and varied by digit. The mean distal extent of the FDS insertion was 8.29 mm. The mean length of the insertion of each FDS slip was 5.15 mm and the mean width was 1.9 mm. The radial and ulnar FDS slips insert on average 3.22 mm distal to the PIP skin crease and vary by digit. Knowledge of the FDS insertion is clinically relevant when differentiating between flexor zone I and zone II injuries, planning surgical approaches to the finger, and in guiding patient expectations for surgery given the variability in outcome based on zone of injury.

  11. Multicoil2: predicting coiled coils and their oligomerization states from sequence in the twilight zone.

    Directory of Open Access Journals (Sweden)

    Jason Trigg

    Full Text Available The alpha-helical coiled coil can adopt a variety of topologies, among the most common of which are parallel and antiparallel dimers and trimers. We present Multicoil2, an algorithm that predicts both the location and oligomerization state (two versus three helices of coiled coils in protein sequences. Multicoil2 combines the pairwise correlations of the previous Multicoil method with the flexibility of Hidden Markov Models (HMMs in a Markov Random Field (MRF. The resulting algorithm integrates sequence features, including pairwise interactions, through multinomial logistic regression to devise an optimized scoring function for distinguishing dimer, trimer and non-coiled-coil oligomerization states; this scoring function is used to produce Markov Random Field potentials that incorporate pairwise correlations localized in sequence. Multicoil2 significantly improves both coiled-coil detection and dimer versus trimer state prediction over the original Multicoil algorithm retrained on a newly-constructed database of coiled-coil sequences. The new database, comprised of 2,105 sequences containing 124,088 residues, includes reliable structural annotations based on experimental data in the literature. Notably, the enhanced performance of Multicoil2 is evident when tested in stringent leave-family-out cross-validation on the new database, reflecting expected performance on challenging new prediction targets that have minimal sequence similarity to known coiled-coil families. The Multicoil2 program and training database are available for download from http://multicoil2.csail.mit.edu.

  12. Metering Wheel-Wire Track Wire Boom Deployment Mechanism

    Science.gov (United States)

    Granoff, Mark S.

    2014-01-01

    The NASA MMS Spin Plane Double Probe (SDP) Deployer utilizes a helical path, rotating Metering Wheel and a spring loaded Wire "Holding" Track to pay out a "fixed end" 57 meter x 1.5 mm diameter Wire Boom stored between concentric storage cylinders. Unlike rotating spool type storage devices, the storage cylinders remain stationary, and the boom wire is uncoiled along the length of the cylinder via the rotation of the Metering Wheel. This uncoiling action avoids the need for slip-ring contacts since the ends of the wire can remain stationary. Conventional fixed electrical connectors (Micro-D type) are used to terminate to operational electronics.

  13. Reduction in wire tension caused by wire clamping and wire tensioner removal: an experimental Ilizarov frame study.

    Science.gov (United States)

    La Russa, Valentina; Skallerud, Bjørn; Klaksvik, Jomar; Foss, Olav A

    2011-03-01

    The stability of an external ring fixator mainly depends on wire tension. Wire fixators should maintain the tension during both wire clamping to the ring and removal of the tensioner device. In the present study the loss in wire tension related to fixator clamping and wire tensioner removal using three different wire fixator designs was studied. The fixators were based on two different cannulated bolts and a washer. Effects from two different pretension levels in combination with three different bolt torque levels upon loss in wire tension were described. Emitted wire vibration frequency was used to assess the corresponding wire tension. Wire tension was determined after each wire fixator tightening and after the removal of the wire tensioner. Increased bolt torque led to a small decrease in tension for both pretension levels. A considerable higher tension loss was measured when removing the wire tensioner. In all cases, the combination of a new cannulated bolt and a washer maintained the highest tension.

  14. High performance twisted and coiled soft actuator with spandex fiber for artificial muscles

    Science.gov (United States)

    Yang, Sang Yul; Cho, Kyeong Ho; Kim, Youngeun; Song, Min-Geun; Jung, Ho Sang; Yoo, Ji Wang; Moon, Hyungpil; Koo, Ja Choon; Nam, Jae-do; Ryeol Choi, Hyouk

    2017-10-01

    This paper reports the twisted and coiled soft actuator (abbreviated with STCA) with spandex fiber. The STCA exhibits higher actuation strain at lower temperature than the previous nylon twisted and coiled soft actuators (abbreviated with NTCAs). While NTCAs are fabricated using a twist-insertion process until coils are formed, a new method is developed to fabricate the STCA using the ultra-stretch of spandex, whereby the STCA is twisted again after the coil has been formed. A 6-gear-twist-insertion device that increases the stability and the fabrication speed is developed to fabricate the STCA. The superior performance exhibited by the STCA is due to the 14% contraction strain of the bare spandex (bare nylon: 4%) and the low spring constant of 0.0115 N mm-1. The maximum tensile actuation strain of STCA was 45% at 130 °C, and the maximum specific work was 1.523 kJ kg-1 at 130 °C. STCA could repeatedly actuate 100 times with a strain change of less than 0.4%.

  15. Review of wire chamber aging

    Energy Technology Data Exchange (ETDEWEB)

    Va' Vra, J.

    1986-02-01

    This paper makes an overview of the wire chamber aging problems as a function of various chamber design parameters. It emphasizes the chemistry point of view and many examples are drawn from the plasma chemistry field as a guidance for a possible effort in the wire chamber field. The paper emphasizes the necessity of variable tuning, the importance of purity of the wire chamber environment, as well as it provides a practical list of presently known recommendations. In addition, several models of the wire chamber aging are qualitatively discussed. The paper is based on a summary talk given at the Wire Chamber Aging Workshop held at LBL, Berkeley on January 16-17, 1986. Presented also at Wire Chamber Conference, Vienna, February 25-28, 1986. 74 refs., 18 figs., 11 tabs.

  16. Basic ideas and concepts in hot wire anemometry: an experimental approach for introductory physics students

    Science.gov (United States)

    El Abed, Mohamed

    2016-01-01

    The purpose of hot wire anemometry is to measure the speed of an air stream. The classical method is based on the measure of the value of a temperature dependant resistor inserted in a Wheatstone bridge (Lomas 1986 Fundamentals of Hot Wire Anemometry (Cambridge: Cambridge University Press)). In this paper we exhibit the physics behind this method and show that by using a wire whose resistance does not vary on the field of temperature explored (from 20 °C to 200 °C), it is however possible to make accurate measurements. Finally, limitations of the method are discussed.

  17. Wiring regulations in brief

    CERN Document Server

    Tricker, Ray

    2012-01-01

    Tired of trawling through the Wiring Regs?Perplexed by Part P?Confused by cables, conductors and circuits?Then look no further! This handy guide provides an on-the-job reference source for Electricians, Designers, Service Engineers, Inspectors, Builders, Students, DIY enthusiastsTopic-based chapters link areas of working practice - such as cables, installations, testing and inspection, special locations - with the specifics of the Regulations themselves. This allows quick and easy identification of the official requirements relating to the situati

  18. Coil Optimization for High Temperature Superconductor Machines

    DEFF Research Database (Denmark)

    Mijatovic, Nenad; Jensen, Bogi Bech; Abrahamsen, Asger Bech

    2011-01-01

    This paper presents topology optimization of HTS racetrack coils for large HTS synchronous machines. The topology optimization is used to acquire optimal coil designs for the excitation system of 3 T HTS machines. Several tapes are evaluated and the optimization results are discussed. The optimiz...

  19. Penile hair coil strangulation of the child

    African Journals Online (AJOL)

    shanker

    amputation of the corpus spongiosum. Grade IV corresponds to the section of the glans [8]. In the majority of the reported cases, the constrictive injury is located in the coronal sulcus. The coil of hair can be so deeply embedded in the skin that the physical examination shows no foreign body coiled around the penis.

  20. Magnetic Fields at the Center of Coils

    Science.gov (United States)

    Binder, Philippe; Hui, Kaleonui; Goldman, Jesse

    2014-01-01

    In this note we synthesize and extend expressions for the magnetic field at the center of very short and very long current-carrying coils. Elementary physics textbooks present the following equation for the magnetic field inside a very long current-carrying coil (solenoid): B[subscript sol] = µ[subscript 0] (N/L) I, (1) where I is the current, N…

  1. Evidence-based pathology: umbilical cord coiling.

    Science.gov (United States)

    Khong, T Y

    2010-12-01

    The generation of a pathology test result must be based on criteria that are proven to be acceptably reproducible and clinically relevant to be evidence-based. This review de-constructs the umbilical cord coiling index to illustrate how it can stray from being evidence-based. Publications related to umbilical cord coiling were retrieved and analysed with regard to how the umbilical coiling index was calculated, abnormal coiling was defined and reference ranges were constructed. Errors and other influences that can occur with the measurement of the length of the umbilical cord or of the number of coils can compromise the generation of the coiling index. Definitions of abnormal coiling are not consistent in the literature. Reference ranges defining hypocoiling or hypercoiling have not taken those potential errors or the possible effect of gestational age into account. Even the way numerical test results in anatomical pathology are generated, as illustrated by the umbilical coiling index, warrants a critical analysis into its evidence base to ensure that they are reproducible or free from errors.

  2. Novel transcranial magnetic stimulation coil for mice

    Science.gov (United States)

    March, Stephen; Stark, Spencer; Crowther, Lawrence; Hadimani, Ravi; Jiles, David

    2014-03-01

    Transcranial magnetic stimulation (TMS) shows potential for non-invasive treatment of various neurological disorders. Significant work has been performed on the design of coils used for TMS on human subjects but few reports have been made on the design of coils for use on the brains of animals such as mice. This work is needed as TMS studies utilizing mice can allow rapid preclinical development of TMS for human disorders but the coil designs developed for use on humans are inadequate for optimal stimulation of the much smaller mouse brain. A novel TMS coil has been developed with the goal of inducing strong and focused electric fields for the stimulation of small animals such as mice. Calculations of induced electric fields were performed utilizing an MRI derived inhomogeneous model of an adult male mouse. Mechanical and thermal analysis of this new TMS helmet-coil design have also been performed at anticipated TMS operating conditions to ensure mechanical stability of the new coil and establish expected linear attraction and rotational force values. Calculated temperature increases for typical stimulation periods indicate the helmet-coil system is capable of operating within established medical standards. A prototype of the coil has been fabricated and characterization results are presented.

  3. Measurements of AC losses in oxide superconducting tapes and coils; Sankabutsu chodendo senzai oyobi koiru no koryu sonshitsu shokutei

    Energy Technology Data Exchange (ETDEWEB)

    Nakagami, M.; Watabe, K.; Kawagoe, A.; Sumiyoshi, F. [Kagoshima Univ., Kagoshima (Japan); Hayashi, H. [Kyushu Electric Power Co., Inc., Fukuoka (Japan)

    1999-06-07

    The application to the electric power equipment is expected oxide superconductivity wire rod, and short length linearity under the operating condition and quantitative evaluation of the ac loss in coil shape are important. Until now, we propose the pointing vector method as loss measuring method of the short length linear sample, and the equipment has been produced experimentally. However, in this measuring method, it was small within the signal of electric field with 10{sup -4}-10{sup -6} at loss component ratio, and there was a problem that the sensitometry was not sufficiently taken, since moreover, they are about number 10nV and weak signal very. Then, noise counterplan method in the measuring circuit, etc. were examined in order to improve the sensitometry this time. In addition, the examination of loss measuring method of the wire rod as coil shape is also reported, because it was done. (NEDO)

  4. Progress in American Superconductor’s HTS wire and optimization for fault current limiting systems

    Energy Technology Data Exchange (ETDEWEB)

    Malozemoff, Alexis P., E-mail: amalozemoff@amsc.com

    2016-11-15

    Highlights: • AMSC HTS wire critical current needed for rotating machinery is doubled by 16 MeV Au irradiation. • Nonuniformity of HTS wires in power devices causes hot spot formation during power system faults. • Lower normal-state resistivity and critical current lower HTS wire hot spot heating during faults. • HTS wire hot spot heating in HTS cables during faults must stay below lN{sub 2} bubble nucleation point. • HTS wire can be designed to meet hot spot heating limits in fault current limiting cables. - Abstract: American Superconductor has developed composite coated conductor tape-shaped wires using high temperature superconductor (HTS) on a flexible substrate with laminated metal stabilizer. Such wires enable many applications, each requiring specific optimization. For example, coils for HTS rotating machinery require increased current density J at 25–50 K. A collaboration with Argonne, Brookhaven and Los Alamos National Laboratories and several universities has increased J using an optimized combination of precipitates and ion irradiation defects in the HTS. Major commercial opportunities also exist to enhance electric power grid resiliency by linking substations with distribution-voltage HTS power cables [10]. Such links provide alternative power sources if one substation's transmission-voltage power is compromised. But they must also limit fault currents which would otherwise be increased by such distribution-level links. This can be done in an HTS cable, exploiting the superconductor-to-resistive transition when current exceeds the wires’ critical J. A key insight is that such transitions are usually nonuniform; so the wire must be designed to prevent localized hot spots from damaging the wire or even generating gas bubbles in the cable causing dielectric breakdown. Analysis shows that local heating can be minimized by increasing the composite tape's total thickness, decreasing its total resistance in the normal state and

  5. Radiative MRI Coil Design Using Parasitic Scatterers

    DEFF Research Database (Denmark)

    Sanchez-Heredia, Juan D.; Avendal, Johan; Bibic, Adnan

    2018-01-01

    Conventionally, radiofrequency (RF) coils used for magnetic resonance imaging (MRI) are electrically small and designed for nearfield operation. Therefore, existing antenna design techniques are mostly irrelevant for RF coils. However, the use of higher frequencies in ultrahigh field (UHF) MRI...... allows for antenna design techniques to be adapted to RF coil designs. This study proposes the use of parasitic scatterers to improve the performance of an existing 7T MRI coil called the single-sided adapted dipole (SSAD) antenna. The results reveal that scatterers arranged in a Yagi fashion can...... suitable for use in high density arrays. These findings show the potential of parasitic scatterers as an effective method to improve the performance of existing radiative MRI coils....

  6. Corrosion of Wires on Wooden Wire-Bound Packaging Crates

    Science.gov (United States)

    Samuel L. Zelinka; Stan Lebow

    2015-01-01

    Wire-bound packaging crates are used by the US Army to transport materials. Because these crates may be exposed to harsh environments, they are dip-treated with a wood preservative (biocide treatment). For many years, zinc-naphthenate was the most commonly used preservative for these packaging crates and few corrosion problems with the wires were observed. Recently,...

  7. Reversible and irreversible coiled coils in the stalk domain of ncd motor protein.

    Science.gov (United States)

    Makino, Tsukasa; Morii, Hisayuki; Shimizu, Takashi; Arisaka, Fumio; Kato, Yusuke; Nagata, Koji; Tanokura, Masaru

    2007-08-21

    Ncd is a microtubule minus end-directed motor protein from Drosophila, a member of the kinesin-14 family, and an essential protein in mitosis and meiosis. Full-length ncd exists as a dimer via the formation of an alpha-helical coiled coil in its central stalk domain (P192-R346), which is thought to be one of the key regions for its motility. In our previous studies, however, none of the various synthetic polypeptide fragments (up to 46 residues) from the stalk domain formed a coiled coil. Herein, we have investigated the structural properties of the full-length ncd stalk domain using recombinant polypeptides together with shorter segments. These new fragments did form coiled coils as verified by far-UV circular dichroism (CD) spectroscopy and analytical ultracentrifugation, suggesting that a certain length of polypeptide would be required for dimer formation. Moreover, deletion mapping revealed that the cooperativity among the neighboring subdomains in the stalk domain is required for formation of the coiled coil. Interestingly, the intact stalk domain segments showed three-state transition in thermal unfolding measurements with CD, indicating the presence of two regions: (i) a coiled-coil region (P227-R306) that exhibits reversible denaturation at a lower temperature (20-30 degrees C) and (ii) a more rigid coiled-coil region (T307-E334) that exhibits irreversible denaturation at a high temperature (ca. 60 degrees C). These results imply that the N-terminal region of the stalk domain might be able to adopt both a coiled-coil conformation and a dissociated one, which might be relevant to the functions of ncd.

  8. An unusual case of intrarenal coiled and ruptured guidewire

    Directory of Open Access Journals (Sweden)

    Francesca Manassero

    2015-03-01

    Full Text Available Objective. To the best of our knowledge there are only 3 reports of fractured guidewires inside the pelvicalyceal system, successfully removed with endourology techniques, and this is the first one presenting a tightly coiled intraparenchymal section. Material and methods: A 59-year-old woman was hospitalized for surgical treatment of a right kidney of reduced size. Past history revealed pyelolithotomy for a staghorn stone 14 months earlier at another Institution with subsequent ureteral obstruction, one failed attempt at ureteral double-J catheter insertion and one failed attempt at percutaneous nephrostomy placement 5 months postoperatively. Another nephrostomy was placed, but left indwelling briefly. CT scan demonstrated a small-size kidney with residual stone fragments and presence of a “device” in the lower pole. The tapered distal extremity of an hydrophilic guidewire, with a tightly coiled central section wedged in the renal tissue was found inside the nephrectomy specimen. Results: While the Radiologist who read the CT scan hypothesized that the “device” was a fragment of double-J ureteral stent or nephrostomy catheter, it consisted of the hydrophilic extremity of a guidewire, broken during a previous attempt at nephostomy placement. Perirenal fibrosis and inappropriate angle between the needle and the lower calyx are the likely causes of guidewire coiling during its advancement and subsequent rupture during withdrawal. Conclusions. Urologists must be aware that, although percutaneous nephrostomy has a very high technical success rate, unusual complications like guidewire fracture may occur, and that modern imaging techniques can provide an accurate picture of this condition.

  9. Modelling of flexi-coil springs with rubber-metal pads in a locomotive running gear

    Directory of Open Access Journals (Sweden)

    Michálek T.

    2015-06-01

    Full Text Available Nowadays, flexi-coil springs are commonly used in the secondary suspension stage of railway vehicles. Lateral stiffness of these springs is influenced by means of their design parameters (number of coils, height, mean diameter of coils, wire diameter etc. and it is often suitable to modify this stiffness in such way, that the suspension shows various lateral stiffness in different directions (i.e., longitudinally vs. laterally in the vehicle-related coordinate system. Therefore, these springs are often supplemented with some kind of rubber-metal pads. This paper deals with modelling of the flexi-coil springs supplemented with tilting rubber-metal tilting pads applied in running gear of an electric locomotive as well as with consequences of application of that solution of the secondary suspension from the point of view of the vehicle running performance. This analysis is performed by means of multi-body simulations and the description of lateral stiffness characteristics of the springs is based on results of experimental measurements of these characteristics performed in heavy laboratories of the Jan Perner Transport Faculty of the University of Pardubice.

  10. Most Wired 2006: measuring value.

    Science.gov (United States)

    Solovy, Alden

    2006-07-01

    As the Most Wired hospitals incorporate information technology into their strategic plans, they combine a"balanced scorecard"approach with classic business analytics to measure how well IT delivers on their goals. To find out which organizations made this year's 100 Most Wired list, as well as those named in other survey categories, go to the foldout section.

  11. Irregular AC loss in a large SMES coil; Ogata SMES koiru no fukisoku koryu sonshitsu

    Energy Technology Data Exchange (ETDEWEB)

    Hamajima, T.; Yoshida, M.; Shimamura, T.; Harada, N.; Tsuda, M. [Yamaguchi Univ., Yamaguchi (Japan); Hanai, S. [Toshiba Corp., Tokyo (Japan); Hirano, N. [Chubu Electric Power Co., Inc., Aichi (Japan); Sato, T. [National Inst. for Fusion Science, Nagoya (Japan)

    2000-05-29

    From the results of a series of tests on SMES model coil, it was confirmed that, in AC loss of large SMES wound with large current capacity cable in conduit (CIC) conductor, there was regular AC loss estimated from the short sample test results of conductor and irregular AC loss observed in a coil condition. Irregular AC loss was estimated being caused by many loops with long time constant between several seconds and about 100 seconds composed inside conductor. The analysis results on loss of each elementary wire in cable showed that number of loops was about 20,000 and there was an existing possibility of many loops. An average value of time constant spectrum was about 18 seconds and is a little shorter than of an average time constant 30 seconds obtained from frequency analysis of AC loss. The maximum value was 150 seconds, and indicated an existing possibility of time constant of about 100 seconds obtained by the test. (NEDO)

  12. Correcting coils in end magnets of accelerators

    Directory of Open Access Journals (Sweden)

    L. R. P. Kassab

    1998-05-01

    Full Text Available We present an empirical investigation of the correcting coils behavior used to homogenize the field distribution of the race-track microtron accelerator end magnets. These end magnets belong to the second stage of the 30.0 MeV cw electron accelerator under construction at IFUSP, the race-track microtron booster, in which the beam energy is raised from 1.97 to 5.1 MeV. The correcting coils are attached to the pole faces and are based on the inhomogeneities of the magnetic field measured. The performance of these coils, when operating the end magnets with currents that differ by ±10% from the one used in the mappings that originated the coils copper leads, is presented. For one of the magnets, adjusting conveniently the current of the correcting coils makes it possible to homogenize field distributions of different intensities, once their shapes are practically identical to those that originated the coils. For the other one, the shapes are changed and the coils are less efficient. This is related to intrinsic factors that determine the inhomogeneities. However, we obtained uniformity of 0.001% in both cases.

  13. 3D Gradient coil design - Toroidal surfaces

    Science.gov (United States)

    While, Peter T.; Forbes, Larry K.; Crozier, Stuart

    2009-05-01

    Gradient coil design typically involves optimisation of current densities or coil windings on familiar cylindrical, planar, spherical or conical surfaces. In this paper, an analytic inverse method is presented for the theoretical design of toroidal transverse gradient coils. This novel geometry is based on previous work involving a 3D current density solution, in which the precise geometry of the gradient coils was obtained as part of the optimisation process. Regularisation is used to solve for the toroidal current densities, whereby the field error is minimised in conjunction with the total power of the coil. The method is applied to the design of unshielded and shielded, whole-body and head coil gradient systems. Preliminary coil windings displaying high gradient homogeneity, low inductance, high efficiency and good force balancing are displayed and discussed. Potential benefits associated with this morphology include self-shielding gradient sets, greater access to cooling mechanisms, a reduction in acoustic noise due to force-balancing, a lessening of patient claustrophobia and greater patient access for clinicians.

  14. Switching transients in a superconducting coil

    Energy Technology Data Exchange (ETDEWEB)

    Owen, E.W.; Shimer, D.W.

    1983-11-18

    A study is made of the transients caused by the fast dump of large superconducting coils. Theoretical analysis, computer simulation, and actual measurements are used. Theoretical analysis can only be applied to the simplest of models. In the computer simulations two models are used, one in which the coil is divided into ten segments and another in which a single coil is employed. The circuit breaker that interrupts the current to the power supply, causing a fast dump, is represented by a time and current dependent conductance. Actual measurements are limited to measurements made incidental to performance tests on the MFTF Yin-yang coils. It is found that the breaker opening time is the critical factor in determining the size and shape of the transient. Instantaneous opening of the breaker causes a lightly damped transient with large amplitude voltages to ground. Increasing the opening time causes the transient to become a monopulse of decreasing amplitude. The voltages at the external terminals are determined by the parameters of the external circuit. For fast opening times the frequency depends on the dump resistor inductance, the circuit capacitance, and the amplitude on the coil current. For slower openings the dump resistor inductance and the current determine the amplitude of the voltage to ground at the terminals. Voltages to ground are less in the interior of the coil, where transients related to the parameters of the coil itself are observed.

  15. Crystal structure of a coiled-coil domain from human ROCK I.

    Directory of Open Access Journals (Sweden)

    Daqi Tu

    Full Text Available The small GTPase Rho and one of its targets, Rho-associated kinase (ROCK, participate in a variety of actin-based cellular processes including smooth muscle contraction, cell migration, and stress fiber formation. The ROCK protein consists of an N-terminal kinase domain, a central coiled-coil domain containing a Rho binding site, and a C-terminal pleckstrin homology domain. Here we present the crystal structure of a large section of the central coiled-coil domain of human ROCK I (amino acids 535-700. The structure forms a parallel α-helical coiled-coil dimer that is structurally similar to tropomyosin, an actin filament binding protein. There is an unusual discontinuity in the coiled-coil; three charged residues (E613, R617 and D620 are positioned at what is normally the hydrophobic core of coiled-coil packing. We speculate that this conserved irregularity could function as a hinge that allows ROCK to adopt its autoinhibited conformation.

  16. Fabrication and calibration of search coils

    CERN Document Server

    Buzio, M

    2010-01-01

    In this paper the techniques available to make and calibrate magnetic search coils are reviewed, with emphasis on harmonic coil systems as the commonly-used optimal choice for integral measurements of accelerator magnets in terms of measuring range, accuracy, and cost. The topics treated, drawing extensively on half a century of experience at CERN, include mechanical and electrical design criteria, practical fabrication techniques, metrological considerations, and various calibration methods for coil parameters such as surface area, rotation radius, tilt angle etc. in both static or time-varying magnetic fields.

  17. Internal trim coils for CBA superconducting magnets

    Energy Technology Data Exchange (ETDEWEB)

    Thompson, P.A.; Aronson, S.; Cottingham, J.G.; Garber, M.; Hahn, H.; Sampson, W.B.

    1983-01-01

    In order to correct iron saturation effects and shape the beam working line, superconducting trim coils have been constructed, which operate inside the main coils. Detailed studies of mechanical properties, quench behavior, fields produced, and hysteresis have lead to the production of accelerator-quality coils generating the required-strength harmonics up to cos (7theta). These are routinely installed in CBA main magnets and operate at 80% of short sample with negligible training in an ambient field of more than 5.3T.

  18. Magnetic field mapper based on rotating coils

    CERN Document Server

    AUTHOR|(CDS)2087244; Arpaia, Pasquale

    This thesis presents a magnetic field mapper based on rotating coils. The requirements, the architecture, the conceptual design, and the prototype for straight magnets were shown. The proposed system is made up of a rotating coil transducer and a train-like system for longitudinal motion and positioning inside magnet bore. The mapper allows a localized measurement of magnetic fields and the variation of the harmonic multipole content in the magnet ends. The proof-of-principle demonstration and the experimental characterization of the rotating-coil transducer specifically conceived for mapping validated the main objective of satisfying the magnetic measurement needs of the next generation of compact accelerators.

  19. Mechanisms for Complex Chromosomal Insertions.

    Science.gov (United States)

    Gu, Shen; Szafranski, Przemyslaw; Akdemir, Zeynep Coban; Yuan, Bo; Cooper, Mitchell L; Magriñá, Maria A; Bacino, Carlos A; Lalani, Seema R; Breman, Amy M; Smith, Janice L; Patel, Ankita; Song, Rodger H; Bi, Weimin; Cheung, Sau Wai; Carvalho, Claudia M B; Stankiewicz, Paweł; Lupski, James R

    2016-11-01

    Chromosomal insertions are genomic rearrangements with a chromosome segment inserted into a non-homologous chromosome or a non-adjacent locus on the same chromosome or the other homologue, constituting ~2% of nonrecurrent copy-number gains. Little is known about the molecular mechanisms of their formation. We identified 16 individuals with complex insertions among 56,000 individuals tested at Baylor Genetics using clinical array comparative genomic hybridization (aCGH) and fluorescence in situ hybridization (FISH). Custom high-density aCGH was performed on 10 individuals with available DNA, and breakpoint junctions were fine-mapped at nucleotide resolution by long-range PCR and DNA sequencing in 6 individuals to glean insights into potential mechanisms of formation. We observed microhomologies and templated insertions at the breakpoint junctions, resembling the breakpoint junction signatures found in complex genomic rearrangements generated by replication-based mechanism(s) with iterative template switches. In addition, we analyzed 5 families with apparently balanced insertion in one parent detected by FISH analysis and found that 3 parents had additional small copy-number variants (CNVs) at one or both sides of the inserting fragments as well as at the inserted sites. We propose that replicative repair can result in interchromosomal complex insertions generated through chromothripsis-like chromoanasynthesis involving two or three chromosomes, and cause a significant fraction of apparently balanced insertions harboring small flanking CNVs.

  20. Mechanisms for Complex Chromosomal Insertions.

    Directory of Open Access Journals (Sweden)

    Shen Gu

    2016-11-01

    Full Text Available Chromosomal insertions are genomic rearrangements with a chromosome segment inserted into a non-homologous chromosome or a non-adjacent locus on the same chromosome or the other homologue, constituting ~2% of nonrecurrent copy-number gains. Little is known about the molecular mechanisms of their formation. We identified 16 individuals with complex insertions among 56,000 individuals tested at Baylor Genetics using clinical array comparative genomic hybridization (aCGH and fluorescence in situ hybridization (FISH. Custom high-density aCGH was performed on 10 individuals with available DNA, and breakpoint junctions were fine-mapped at nucleotide resolution by long-range PCR and DNA sequencing in 6 individuals to glean insights into potential mechanisms of formation. We observed microhomologies and templated insertions at the breakpoint junctions, resembling the breakpoint junction signatures found in complex genomic rearrangements generated by replication-based mechanism(s with iterative template switches. In addition, we analyzed 5 families with apparently balanced insertion in one parent detected by FISH analysis and found that 3 parents had additional small copy-number variants (CNVs at one or both sides of the inserting fragments as well as at the inserted sites. We propose that replicative repair can result in interchromosomal complex insertions generated through chromothripsis-like chromoanasynthesis involving two or three chromosomes, and cause a significant fraction of apparently balanced insertions harboring small flanking CNVs.

  1. Insertion device and method for accurate and repeatable target insertion

    Science.gov (United States)

    Gubeli, III, Joseph F.; Shinn, Michelle D.; Bevins, Michael E.; Dillon-Townes, Lawrence; Neil, George R.

    2017-07-04

    The present invention discloses a device and a method for inserting and positioning a target within a free electron laser, particle accelerator, or other such device that generates or utilizes a beam of energy or particles. The system includes a three-point registration mechanism that insures angular and translational accuracy and repeatability of positioning upon multiple insertions within the same structure.

  2. Repair of olecranon fractures using fiberWire without metallic implants: report of two cases

    Directory of Open Access Journals (Sweden)

    Okawa Atsushi

    2010-10-01

    Full Text Available Abstract Olecranon fractures are a common injury in fractures. The tension band technique for olecranon fractures yields good clinical outcomes; however, it is associated with significant complications. In many patients, implants irritate overlying soft tissues and cause pain. This is mostly due to protrusion of the proximal ends of the K-wires or by the twisted knots of the metal wire tension band. Below we described 2 cases of olecranon fractures treated with a unique technique using FiberWire without any metallic implants. Technically, the fragment was reduced, and two K-wires were inserted from the dorsal cortex of the distal segment to the tip of the olecranon. K-wire was exchanged for a suture retriever, and 2 strands of FiberWire were retrieved twice. Each of the two FiberWires was manually tensioned and knotted on the posterior surface of the olecranon. Bony unions could be achieved, and patients had no complaint of pain and skin irritation. There was only a small loss of flexion and extension in comparison with that of the contralateral side, and the patient did not feel inconvenienced in his daily life. Using the method described, difficulty due to K-wire or other metallic implants was avoided.

  3. A coil test facility for the cryogenic tests of the JT-60SA TF coils

    Energy Technology Data Exchange (ETDEWEB)

    Chantant, M., E-mail: michel.chantant@cea.fr [CEA/DSM/IRFM, F-13108 Saint Paul-lez-Durance (France); Genini, L. [CEA/DSM/Irfu CEA-Saclay, F-91191 Gif-sur-Yvette Cedex (France); Bayetti, P. [CEA/DSM/IRFM, F-13108 Saint Paul-lez-Durance (France); Millet, F. [CEA/DSM/INAC, F-38054 Grenoble Cedex (France); Wanner, M. [F4E, Broader Fusion Development Department Boltzmannstr.2, D-85748 Garching (Germany); Massaut, V. [SCK/CEN Boeretang 200 2400 Mol (Belgium); Corte, A. Della [ENEA CRE Frascati Via Enrico Fermi 45 CP65 00044 frascati Italy (Italy); Ardelier-Desage, F. [CEA/DSM/Irfu CEA-Saclay, F-91191 Gif-sur-Yvette Cedex (France); Catherine-Dumont, V. [CEA/DSM/IRFM, F-13108 Saint Paul-lez-Durance (France); Dael, A. [CEA/DSM/Irfu CEA-Saclay, F-91191 Gif-sur-Yvette Cedex (France); Decool, P. [CEA/DSM/IRFM, F-13108 Saint Paul-lez-Durance (France); Donati, A. [CEA/DSM/Irfu CEA-Saclay, F-91191 Gif-sur-Yvette Cedex (France); Duchateau, J.L.; Garibaldi, P.; Girard, S.; Hatchressian, J.C.; Fejoz, P. [CEA/DSM/IRFM, F-13108 Saint Paul-lez-Durance (France); Jamotton, P. [CSL-LIEGE Science Park, Avenue du Pre-Aily, 4031 Angleur (Belgium); Jourdheuil, L. [CEA/DSM/IRFM, F-13108 Saint Paul-lez-Durance (France); Juster, F.P. [CEA/DSM/Irfu CEA-Saclay, F-91191 Gif-sur-Yvette Cedex (France)

    2011-10-15

    In the framework of the Broader Approach Activities, the EU will deliver to Japan the 18 superconducting coils, which constitute the JT-60SA Toroidal field magnet. These 18 coils, manufactured by France and Italy, will be cold tested before shipping to Japan. For this purpose, the European Joint Undertaking for ITER, the Development of Fusion Energy ('Fusion for Energy', F4E) and the European Voluntary Contributors are collaborating to design and set-up a coil test facility (CTF) and to perform the acceptance test of the 18 JT-60SA Toroidal Field (TF) coils. The test facility is designed to test one coil at a time at nominal current and cryogenic temperature. The test of the first coil of each manufacturer includes a quench triggered by increasing the temperature. The project is presently in the detailed design phase.

  4. Plasma chemistry in wire chambers

    Energy Technology Data Exchange (ETDEWEB)

    Wise, J.

    1990-05-01

    The phenomenology of wire chamber aging is discussed and fundamentals of proportional counters are presented. Free-radical polymerization and plasma polymerization are discussed. The chemistry of wire aging is reviewed. Similarities between wire chamber plasma (>1 atm dc-discharge) and low-pressure rf-discharge plasmas, which have been more widely studied, are suggested. Construction and use of a system to allow study of the plasma reactions occurring in wire chambers is reported. A proportional tube irradiated by an {sup 55}Fe source is used as a model wire chamber. Condensable species in the proportional tube effluent are concentrated in a cryotrap and analyzed by gas chromatography/mass spectrometry. Several different wire chamber gases (methane, argon/methane, ethane, argon/ethane, propane, argon/isobutane) are tested and their reaction products qualitatively identified. For all gases tested except those containing methane, use of hygroscopic filters to remove trace water and oxygen contaminants from the gas resulted in an increase in the average molecular weight of the products, consistent with results from low-pressure rf-discharge plasmas. It is suggested that because water and oxygen inhibit polymer growth in the gas phase that they may also reduce polymer deposition in proportional tubes and therefore retard wire aging processes. Mechanistic implications of the plasma reactions of hydrocarbons with oxygen are suggested. Unresolved issues in this work and proposals for further study are discussed.

  5. Computational characterization of parallel dimeric and trimeric coiled-coils using effective amino acid indices.

    Science.gov (United States)

    Li, Chen; Wang, Xiao-Feng; Chen, Zhen; Zhang, Ziding; Song, Jiangning

    2015-02-01

    The coiled-coil, which consists of two or more α-helices winding around each other, is a ubiquitous and the most frequently observed protein-protein interaction motif in nature. The coiled-coil is known for its straightforward heptad repeat pattern and can be readily recognized based on protein primary sequences, exhibiting a variety of oligomer states and topologies. Due to the stable interaction formed between their α-helices, coiled-coils have been under close scrutiny to design novel protein structures for potential applications in the fields of material science, synthetic biology and medicine. However, their broader application requires an in-depth and systematic analysis of the sequence-to-structure relationship of coiled-coil folding and oligomeric formation. In this article, we propose a new oligomerization state predictor, termed as RFCoil, which exploits the most useful and non-redundant amino acid indices combined with the machine learning algorithm - random forest (RF) - to predict the oligomeric states of coiled-coil regions. Benchmarking experiments show that RFCoil achieves an AUC (area under the ROC curve) of 0.849 on the 10-fold cross-validation test using the training dataset and 0.855 on the independent test using the validation dataset, respectively. Performance comparison results indicate that RFCoil outperforms the four existing predictors LOGICOIL, PrOCoil, SCORER 2.0 and Multicoil2. Furthermore, we extract a number of predominant rules from the trained RF model that underlie the oligomeric formation. We also present two case studies to illustrate the applicability of the extracted rules to the prediction of coiled-coil oligomerization state. The RFCoil web server, source codes and datasets are freely available for academic users at http://protein.cau.edu.cn/RFCoil/.

  6. MR angiography after coiling of intracranial aneurysms

    NARCIS (Netherlands)

    Schaafsma, J.D.

    2012-01-01

    Introduction Endovascular occlusion with detachable coils has become an alternative treatment to neurosurgical clipping of intracranial aneurysms over the last two decades. Its minimal invasiveness is the most important advantage of this treatment compared to clipping. The disadvantage of occlusion

  7. Heterogeneous Superconducting Low-Noise Sensing Coils

    Science.gov (United States)

    Hahn, Inseob; Penanen, Konstantin I.; Ho Eom, Byeong

    2008-01-01

    A heterogeneous material construction has been devised for sensing coils of superconducting quantum interference device (SQUID) magnetometers that are subject to a combination of requirements peculiar to some advanced applications, notably including low-field magnetic resonance imaging for medical diagnosis. The requirements in question are the following: The sensing coils must be large enough (in some cases having dimensions of as much as tens of centimeters) to afford adequate sensitivity; The sensing coils must be made electrically superconductive to eliminate Johnson noise (thermally induced noise proportional to electrical resistance); and Although the sensing coils must be cooled to below their superconducting- transition temperatures with sufficient cooling power to overcome moderate ambient radiative heat leakage, they must not be immersed in cryogenic liquid baths. For a given superconducting sensing coil, this combination of requirements can be satisfied by providing a sufficiently thermally conductive link between the coil and a cold source. However, the superconducting coil material is not suitable as such a link because electrically superconductive materials are typically poor thermal conductors. The heterogeneous material construction makes it possible to solve both the electrical- and thermal-conductivity problems. The basic idea is to construct the coil as a skeleton made of a highly thermally conductive material (typically, annealed copper), then coat the skeleton with an electrically superconductive alloy (typically, a lead-tin solder) [see figure]. In operation, the copper skeleton provides the required thermally conductive connection to the cold source, while the electrically superconductive coating material shields against Johnson noise that originates in the copper skeleton.

  8. Umbilical coiling index & the perinatal outcome.

    Science.gov (United States)

    Devaru, Dakshayini; Thusoo, Meghna

    2012-02-01

    To correlate the perinatal outcome by noting the umbilical coiling index. The umbilical cords of the babies born to 100 women, who delivered either vaginally or by lower segment cesarean section, were examined and umbilical coiling index was calculated. There was significant correlation (p value 0.003) between the hypercoiled cords (UCI >90th percentile) and intrauterine growth restriction of the babies. Apgar score at 1 min UCI UCI UCI >10th percentile is associated with intra uterine growth restriction.

  9. NUMERICAL INVESTIGATION FOR THE HEAT TRANSFER ENHANCEMENT IN HELICAL CONE COILS OVER ORDINARY HELICAL COILS

    Directory of Open Access Journals (Sweden)

    M. M. ABO ELAZM

    2013-02-01

    Full Text Available This numerical research is introducing the concept of helical cone coils and their enhanced heat transfer characteristics compared to the ordinary helical coils. Helical and spiral coils are known to have better heat and mass transfer than straight tubes, which is attributed to the generation of a vortex at the helical coil known as Dean Vortex. The Dean number which is a dimensionless number used to describe the Dean vortex is a function of Reynolds number and the square root of the curvature ratio, so varying the curvature ratio for the same coil would vary the Dean number. Two scenarios were adopted to study the effect of changing the taper angle (curvature ratio on the heat transfer characteristics of the coil; the commercial software FLUENT was used in the investigation. It was found that Nusselt number increased with increasing the taper angle. A MATLAB code was built based on empirical correlation of Manlapaz and Churchill for ordinary helical coils to calculate the Nusselt number at each coil turn, and then calculate the average Nusselt number for the entire coil turns, the CFD simulation results were found acceptable when compared with the MATLAB results.

  10. Coiled coil in the stalk region of ncd motor protein is nonlocally sustained.

    Science.gov (United States)

    Ito, Mie; Morii, Hisayuki; Shimizu, Takashi; Tanokura, Masaru

    2006-03-14

    The dimeric structure of kinesin superfamily proteins plays an important role in their motile functions and characteristics. In this study, the coiled-coil-forming property of the stalk region (192-346) of Drosophila ncd, a C-terminal kinesin motor protein, was investigated by synthesizing various peptide fragments. The alpha helicity of a set of 46-residue peptides spanning the stalk region appeared too low to form a coiled-coil dimer, probably because of insufficient continuity of the hydrophobic residues at (a and d) core positions in amphipathic heptad repeats. On the other hand, several peptides with leucine residues introduced at core positions or with extensional sequences with high alpha helicity had an advantage in coiled-coil formation. When we analyzed the thermal and urea-induced unfolding of these dimeric peptides, we identified four domains having a relatively high potential to form coiled coils. Among them, three domains on the C-terminal side of the stalk region, i.e., (252-272), (276-330), and (336-346), were in the same heptad frame, although these potential coiled-coil domains were not self-sustaining individually. This is in sharp contrast to the fragment of human kinesin, (332-369), which has an extremely high tendency toward coiled-coil formation. One of the possible triggers for coiled-coil formation of the ncd stalk region may be the interaction between the motor domain and the C-terminal part of the stalk as previously revealed by X-ray crystallography. The residues, S331 and R335, seem to act as a breaking point for alpha-helix continuity. This would make the region (336-346), as the head-stalk joint, more flexible such as seen with a plus-end-directed kinesin, if this region had no interaction with the motor domain. These characteristic differences between ncd and kinesin suggest that the nonlocally sustained coiled coil of ncd is one of the factors important for minus-end-directed motility.

  11. pH sensitive coiled coils: a strategy for enhanced liposomal drug delivery

    Science.gov (United States)

    Reja, Rahi M.; Khan, Mohsina; Singh, Sumeet K.; Misra, Rajkumar; Shiras, Anjali; Gopi, Hosahudya N.

    2016-02-01

    Stimuli responsive controlled release from liposome based vesicles is a promising strategy for the site specific delivery of drugs. Herein, we report the design of pH sensitive coiled coils and their incorporation into the liposome as triggers for the controlled release of encapsulated drugs. The designed coiled coil peptides with the incorporation of environment sensitive fluorescent amino acids were found to be stable at physiological pH and unstructured while changing the pH of the environment to either acidic or basic. This pH dependent conformational switch of the coiled-coil polypeptides was exploited as triggers for the enhanced release of the encapsulated drug molecules from liposomes. The SEM, DLS and TEM analysis revealed the uniform morphology of the peptide liposome hybrid vesicles. Further, the drug encapsulated liposome internalization experiments with cancer cells revealed the enhanced release and accumulation of drugs in the acidic lysosomal compartments in comparison with liposomes without coiled coils.Stimuli responsive controlled release from liposome based vesicles is a promising strategy for the site specific delivery of drugs. Herein, we report the design of pH sensitive coiled coils and their incorporation into the liposome as triggers for the controlled release of encapsulated drugs. The designed coiled coil peptides with the incorporation of environment sensitive fluorescent amino acids were found to be stable at physiological pH and unstructured while changing the pH of the environment to either acidic or basic. This pH dependent conformational switch of the coiled-coil polypeptides was exploited as triggers for the enhanced release of the encapsulated drug molecules from liposomes. The SEM, DLS and TEM analysis revealed the uniform morphology of the peptide liposome hybrid vesicles. Further, the drug encapsulated liposome internalization experiments with cancer cells revealed the enhanced release and accumulation of drugs in the acidic

  12. Parallel wire balloon angioplasty for undilatable venous stenosis in hemodialysis fistula

    Energy Technology Data Exchange (ETDEWEB)

    Shin, Tae Beom; You, Jin Jong; Cho, Jae Min [Gyeongsang National University Hospital, Jinju (Korea, Republic of)] (and others)

    2007-05-15

    The purpose of this study was to assess the value of the parallel wire balloon angioplasty technique for treating dysfunctional hemdialysis fistula with rigid stenosis, and this type of lesion was resistant to conventional angioplasty. Between March 2002 and August 2003, we included 6 patients (mean age: 59, males: 2, females: 4) who were treated via parallel the wire balloon angioplasty technique and their hemodialysis fistula has stenoses that were resistant to conventional angioplasty. We performed conventional angioplasty in all patients, but we failed to achieve sufficient dilatation. In the cases of highly resistant stenosis, an additional 0.016 inch wire was inserted into the 7 F vascular sheath. During angioplasty, a 0.016 inch guide wire was inserted between the balloon and the stenosis and then it was pushed to and fro until the balloon indentation disappeared. After the procedure, we performed angiography to identify the residual stenosis and the procedure-related complications. The undilatable stenoses in 5 patients were successfully resolved without complications via the parallel wire angioplasty technique. In one patient, indentation of balloon was not resolved, but the residual stenosis was both minimal and hemodynamically insignificant. The parallel wire angioplasty technique seems to be a feasible and cost-effective method for treating a dysfunctional hemodialysis fistula with undilatable and rigid stenosis.

  13. Optimizing stellarator coil winding surfaces with Regcoil

    Science.gov (United States)

    Bader, Aaron; Landreman, Matt; Anderson, David; Hegna, Chris

    2017-10-01

    We show initial attempts at optimizing a coil winding surface using the Regcoil code [1] for selected quasi helically symmetric equilibria. We implement a generic optimization scheme which allows for variation of the winding surface to allow for improved diagnostic access and allow for flexible divertor solutions. Regcoil and similar coil-solving algorithms require a user-input winding surface, on which the coils lie. Simple winding surfaces created by uniformly expanding the plasma boundary may not be ideal. Engineering constraints on reactor design require a coil-plasma separation sufficient for the introduction of neutron shielding and a tritium generating blanket. This distance can be the limiting factor in determining reactor size. Furthermore, expanding coils in other regions, where possible, can be useful for diagnostic and maintenance access along with providing sufficient room for a divertor. We minimize a target function that includes as constraints, the minimum coil-plasma distance, the winding surface volume, and the normal magnetic field on the plasma boundary. Results are presented for two quasi-symmetric equilibria at different aspect ratios. Work supported by the US DOE under Grant DE-FG02-93ER54222.

  14. Comparison of bare metal and statin-coated coils on rates of intra-aneurysmal tissue organization in a rat model of aneurysm.

    Science.gov (United States)

    Kodama, Tomonobu; Iwata, Hiroo

    2013-05-01

    Endovascular treatment of intracranial aneurysms with detachable coils has been accepted widely. Problems of coil compaction, recanalization and rare endothelialization at the aneurysm orifice are not yet solved. We investigated the efficacy of a simvastatin coating applied without any additional matrix to coils to accelerate thrombus organization in the cavity in a rat model of aneurysm. Twelve metal coils coated with simvastatin and 12 bare coils were inserted into the ligated external carotid arterial (ECA) sacs of rats. The ECA sacs were removed 2 or 4 weeks after the coils were implanted and examined by histology and immunohistochemical assay. The organized areas in the ECA sacs in the simvastatin group (73.6 ± 19.4%, 2 wk; 83.4 ± 11.1%, 4 wk) was significantly higher p = 0.003, 2 wk; p = 0.0004, 4 wk than the bare metal group at 2 and 4 weeks (20.5 ± 10.7%, 2 wk, p ECA sac. We suggest that coating coils with simvastatin effectively accelerated organization within the aneurysms and endothelialization over the coil. Copyright © 2013 Wiley Periodicals, Inc.

  15. Intramedullary wire fixation for unstable forearm fractures in children.

    Science.gov (United States)

    Altay, Murat; Aktekin, Cem Nuri; Ozkurt, Bülent; Birinci, Bariş; Ozturk, Akif Muhtar; Tabak, A Yalçin

    2006-10-01

    Displaced fractures of the diaphyseal forearm in children are often treated conservatively, but there is relatively high incidence of redisplacement, malunion and consequent limitation of function. This retrospective study was performed to determine means for minimalising the complications of intramedullary Kirschner (K)-wire fixation used in the treatment of unstable, diaphyseal forearm fractures by pointing out those which most frequently occur with this treatment choice. This treatment method was applied in 48 children with a mean age of 10.3 (range, 5-14) years. A limited open reduction to one or both bones was necessary for insertion of the intramedullary wire in 20 (40%) patients. Although 24 complications, such as pin site infection, loss of forearm rotation, superficial branch of radial nerve palsy, delayed union, nonunion, hardware migration, and K-wire penetration to the opposite cortex, were recorded in 18 patients, 46 patients (96%) had excellent or good, 1 patient (2%) had fair and 1 patient (2%) had poor outcome using the grading scheme adapted by Price. Except for the patient in whom the fracture was not united, the average union time was 6.3 weeks in children less than 10 years and 7.8 weeks in those above 10 years of age. Despite these minor complications, percutaneous intramedullary fixation with K-wires and proper technique is an appropriate, effective and safe operation for unstable diaphyseal fractures of the forearm in children who cannot be treated by closed manipulation.

  16. Cavity Mode Related Wire Breaking of the SPS Wire Scanners and Loss Measurements of Wire Materials

    CERN Document Server

    Caspers, Friedhelm; Jensen, E; Koopman, J; Malo, J F; Roncarolo, F

    2003-01-01

    During the SPS high intensity run 2002 with LHC type beam, the breaking of several of the carbon wires in the wire scanners has been observed in their parking position. The observation of large changes in the wire resistivity and thermionic electron emission clearly indicated strong RF heating that was depending on the bunch length. A subsequent analysis in the laboratory, simulating the beam by two probe antennas or by a powered stretched wire, showed two main problems: i) the housing of the wire scanner acts as a cavity with a mode spectrum starting around 350 MHz and high impedance values around 700 MHz; ii) the carbon wire used so far appears to be an excellent RF absorber and thus dissipates a significant part of the beam-induced power. Different wire materials are compared with the classical cavity mode technique for the determination of the complex permittivity in the range of 2-4 GHz. As a resonator a rectangular TE_01n type device is utilized.

  17. Cavity mode related wire breaking of the SPS Wire Scanners and loss measurements of wire materials

    CERN Document Server

    Roncarolo, Federico

    2003-01-01

    During the SPS high intensity run 2002 with LHC type beam, the breaking of several of the carbon wires in the wire scanners has been observed in their parking position. The observation of large changes in the wire resistivity and thermionic electron emission clearly indicated strong RF heating that was depending on the bunch length. A subsequent analysis in the laboratory, simulating the beam by two probe antennas or by a powered stretched wire, showed two main problems: i) the housing of the wire scanner acts as a cavity with a mode spectrum starting around 350MHz and high impedance values around 700 MHz; ii) the carbon wire used so far appears to be an excellent RF absorber and thus dissipates a significant part of the beam-induced power. Different wire materials are compared with the classical cavity mode technique for the determination of the complex permittivity in the range of 2-4 GHz. As a resonator a rectangular TE01n type device is utilized.

  18. Mechanical Design and Characteristics of a Superconducting Insertion Quadrupole Model Magnet for the Large Hadron Collider

    CERN Document Server

    Kirby, G A; Ostojic, R; Taylor, T M; Terashima, A; Higashi, N; Higashi, H; Kawamata, H; Ogitsu, T; Shintomi, T; Tanaka, K; Tsuchiya, K; Vanenkov, I; Yamamoto, A

    1999-01-01

    A superconducting insertion quadruple is being developed by KEK in collaboration with CERN for the Large Hadron Collider (LHC) project. The mechanical design of the magnet in which the pre-stress is applied to the coil through thin stainless steel collars inside the yoke, the two halves of which are held together by means of keys, has been validated experimentally by measurements on a short model. The 140 mm long model was assembled from real magnet components in order to simulate the magnet assembly and to evaluate the change in coil pre-stress during assembly and cool-down. A new technique using capacitance pressure transducers was used, which has enabled measurements of the stress distributions in the coil with high accuracy. This paper describes the mechanical design of the quadrupole magnet and results obtained from the short mechanical model.

  19. Technique for reduction of mechanical losses in AC superconducting coils due to thermal expansion properties of various FRP bobbins

    Science.gov (United States)

    Sekine, N.; Tada, S.; Higuchi, T.; Furumura, Y.; Takao, T.; Yamanaka, A.

    2005-10-01

    We reported about reduction of mechanical losses in AC superconducting coils. The method is the use of FRP bobbins fabricated with special fibers. Since their FRPs have negative thermal expansion coefficient to the fiber direction, the FRP bobbins expand to the circumferential direction during cooling down. In case of the superconducting coils with such FRP bobbins, the winding tensions do not decrease during cooling down. Therefore, the mechanical losses are reduced by the suppression of wire's vibration. Their special FRPs are a Dyneema® fiber reinforced plastic (DFRP), a Dyneema and glass fiber reinforced plastic (DGFRP), and a Zylon® fiber reinforced plastic (ZFRP). These materials have negative thermal expansion coefficient to the fiber direction, however, the amplitudes of thermal expansion are various by the quantity or quality of the fiber. In this paper, the values of thermal expansion were actually measured, and it was discussed about the influence on the mechanical losses. At the experimental results, the mechanical loss was small, so that the thermal strain to the circumferential direction on the coil was large. Moreover, in case of the coils with sufficiently strong winding tensions at coil-operating temperature, the mechanical losses vanished.

  20. Technique for reduction of mechanical losses in AC superconducting coils due to thermal expansion properties of various FRP bobbins

    Energy Technology Data Exchange (ETDEWEB)

    Sekine, N. [Tsukamoto Laboratory, Faculty of Engineering, Yokohama National University, 79-5, Tokiwadai, Hodogaya-ku, Yokohama 240-8501 (Japan)]. E-mail: n-sekine@tsukalab.dnj.ynu.ac.jp; Tada, S. [Sophia University, 7-1, Kioicho, Chiyoda-ku, Tokyo 102-8554 (Japan); Higuchi, T. [Sophia University, 7-1, Kioicho, Chiyoda-ku, Tokyo 102-8554 (Japan); Furumura, Y. [Sophia University, 7-1, Kioicho, Chiyoda-ku, Tokyo 102-8554 (Japan); Takao, T. [Sophia University, 7-1, Kioicho, Chiyoda-ku, Tokyo 102-8554 (Japan); Yamanaka, A. [Research Center, Toyobo, Co., Ltd, 2-1-1, Katata, Otsu, Shiga 520-0292 (Japan)

    2005-10-01

    We reported about reduction of mechanical losses in AC superconducting coils. The method is the use of FRP bobbins fabricated with special fibers. Since their FRPs have negative thermal expansion coefficient to the fiber direction, the FRP bobbins expand to the circumferential direction during cooling down. In case of the superconducting coils with such FRP bobbins, the winding tensions do not decrease during cooling down. Therefore, the mechanical losses are reduced by the suppression of wire's vibration. Their special FRPs are a Dyneema[reg] fiber reinforced plastic (DFRP), a Dyneema and glass fiber reinforced plastic (DGFRP), and a Zylon[reg] fiber reinforced plastic (ZFRP). These materials have negative thermal expansion coefficient to the fiber direction, however, the amplitudes of thermal expansion are various by the quantity or quality of the fiber. In this paper, the values of thermal expansion were actually measured, and it was discussed about the influence on the mechanical losses. At the experimental results, the mechanical loss was small, so that the thermal strain to the circumferential direction on the coil was large. Moreover, in case of the coils with sufficiently strong winding tensions at coil-operating temperature, the mechanical losses vanished.

  1. Modeling birds on wires.

    Science.gov (United States)

    Aydoğdu, A; Frasca, P; D'Apice, C; Manzo, R; Thornton, J M; Gachomo, B; Wilson, T; Cheung, B; Tariq, U; Saidel, W; Piccoli, B

    2017-02-21

    In this paper we introduce a mathematical model to study the group dynamics of birds resting on wires. The model is agent-based and postulates attraction-repulsion forces between the interacting birds: the interactions are "topological", in the sense that they involve a given number of neighbors irrespective of their distance. The model is first mathematically analyzed and then simulated to study its main properties: we observe that the model predicts birds to be more widely spaced near the borders of each group. We compare the results from the model with experimental data, derived from the analysis of pictures of pigeons and starlings taken in New Jersey: two different image elaboration protocols allow us to establish a good agreement with the model and to quantify its main parameters. We also discuss the potential handedness of the birds, by analyzing the group organization features and the group dynamics at the arrival of new birds. Finally, we propose a more refined mathematical model that describes landing and departing birds by suitable stochastic processes. Copyright © 2016 Elsevier Ltd. All rights reserved.

  2. Three-axis orthogonal transceiver coil for eddy current sounding

    Science.gov (United States)

    Sukhanov, D.; Zavyalova, K.; Goncharik, M.

    2017-08-01

    We propose the new structure of three-axis transceiver magnetic-induction coil for eddy current probing. Due to the orientation of the coils, the direct signal from the transmitting coil to the receiving coil is minimized, which provided a high dynamic range. Sensitivity in all directions is provided by combining coils of different orientations. Numerical simulation and experimental studies of such a system have been carried out and confirmed the applicability of the proposed method and the mathematical model.

  3. Development of automatic steel coil recognition system for automated crane

    OpenAIRE

    Nishibe, Kunihiko; Fujiwara, Naofumi

    1999-01-01

    An automatic steel coil recognition system with two types of laser-assisted range sensor has been developed for full automated crane operation in the steel coil yard. Performance tests of recognizing full scale model coils were carried out by mounting the recognition system on a full size crane. As a result, recognition accuracy of coil center position, coil diameter and width were confirmed to be ±20 mm, which is enough fur practical applications. This recognition system was delivered to com...

  4. Topology Optimized Photonic Wire Splitters

    DEFF Research Database (Denmark)

    Frandsen, Lars Hagedorn; Borel, Peter Ingo; Jensen, Jakob Søndergaard

    2006-01-01

    Photonic wire splitters have been designed using topology optimization. The splitters have been fabricated in silicon-on-insulator material and display broadband low-loss 3dB splitting in a bandwidth larger than 100 nm.......Photonic wire splitters have been designed using topology optimization. The splitters have been fabricated in silicon-on-insulator material and display broadband low-loss 3dB splitting in a bandwidth larger than 100 nm....

  5. Tissue encapsulation of the proximal Essure micro-insert from the uterine cavity following hysteroscopic sterilization.

    Science.gov (United States)

    Kerin, John F; Munday, David; Ritossa, Martin; Rosen, David

    2007-01-01

    To assess the interaction between the trailing ends of a sterilization micro-insert extending into the uterine cavity and the surrounding uterine tissue environment over time. Multicenter, retrospective observational study (Canadian Task Force classification II-1). Hospital-based clinical research centers. A subset of a study population of 545 women who had undergone a hysteroscopic sterilization procedure. A second-look hysteroscopy was performed in 22 (20 with uterine bleeding, 2 pre IVF) of these 545 women between 4 and 43 months from the sterilization procedure. Over a mean time period of 19.73 months, the trailing coils of the micro-inserts into the uterine cavity shortened from a mean of 5.7 mm to 2.0 mm and from 5.4 mm to 1.8 mm on the right and left sides, respectively. In cases observed within 12 months or fewer post-procedure, the complete tissue encapsulation of both micro-inserts had already occurred in 17% of the observations. Among cases evaluated from 13 to 43 months post-procedure, 25% evidenced complete encapsulation. Two mechanisms appear to be responsible for this process. First, there is an initial mechanical "winding-in" of the micro-insert of approximately 1 rotation of its outer coil, accounting for 1 mm of its length, after release from its delivery system. Second, the tissue around the ostium appears to use the trailing coils of the micro-insert as a scaffolding structure, gradually encapsulating and excluding them from the uterine cavity. The gradual tissue exclusion of the micro-insert from the uterine cavity may make it pregnancy-compatible after in vitro fertilization and embryo transfer procedures.

  6. 30 CFR 75.701-4 - Grounding wires; capacity of wires.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Grounding wires; capacity of wires. 75.701-4... SAFETY AND HEALTH MANDATORY SAFETY STANDARDS-UNDERGROUND COAL MINES Grounding § 75.701-4 Grounding wires; capacity of wires. Where grounding wires are used to ground metallic sheaths, armors, conduits, frames...

  7. 1 mil gold bond wire study.

    Energy Technology Data Exchange (ETDEWEB)

    Huff, Johnathon; McLean, Michael B.; Jenkins, Mark W.; Rutherford, Brian Milne

    2013-05-01

    In microcircuit fabrication, the diameter and length of a bond wire have been shown to both affect the current versus fusing time ratio of a bond wire as well as the gap length of the fused wire. This study investigated the impact of current level on the time-to-open and gap length of 1 mil by 60 mil gold bond wires. During the experiments, constant current was provided for a control set of bond wires for 250ms, 410ms and until the wire fused; non-destructively pull-tested wires for 250ms; and notched wires. The key findings were that as the current increases, the gap length increases and 73% of the bond wires will fuse at 1.8A, and 100% of the wires fuse at 1.9A within 60ms. Due to the limited scope of experiments and limited data analyzed, further investigation is encouraged to confirm these observations.

  8. Characteristics analysis on a superconductor resonance coil WPT system according to cooling vessel materials in different distances

    Energy Technology Data Exchange (ETDEWEB)

    Jeong, In-Sung, E-mail: no21park@hanmail.net; Lee, Yu-Kyeong; Choi, Hyo-Sang, E-mail: hyosang@chosun.ac.kr

    2016-11-15

    Highlights: • WPT using the superconductor coil was needed research for cooling vessel. FRP, bakelite, polystyrene, aluminum, and iron were applied as the cooling vessel material to analyze the WPT distance efficiency. • When the distance between the transmitter and receiver coils was 2000 mm, FRP being used for the cooling vessel made the transmission efficiency higher than any other materials. The efficiency and distance of sending power can be improved in the superconductor coil if the cooling vessel is made with FRP. - Abstract: The interest in wireless power transfer (WPT) that can send power without using wires has been increasing recently. Especially, there is a great interest in the wireless power devices for portable IT devices. The WPT devices that have been developed so far use the magnetic induction method, and they are not active due to their distance problem. A magnetic resonance WPT method was developed and has been actively researched to resolve this problem. A superconductor coil was applied in this study to increase the efficiency of the magnetic resonance WPT. FRP, bakelite, polystyrene, aluminum, and iron were applied as the cooling vessel material to analyze the WPT distance. The distance between the transmitter and receiver coils started from 800 mm and was increased by 200 mm. The reflection coefficient was measured at each distance. As a result, FRP, bakelite, plastic PVC, polystyrene of the reflection coefficient was similar. From among these FRP being used for the cooling vessel made the transmission characteristics higher than any other materials when the distance between the transmitter and receiver coils was 2,000 mm. On the other hand, the reflection coefficient dropped when iron was used. It is estimated based on the experimental results that the wireless power transmission characteristics and distance of sending power can be improved in the superconductor coil if the cooling vessel is made with FRP.

  9. Tensile actuators of carbon nanotube coiled yarn based on polydiacetylene-pluronic copolymers as temperature indicators

    Science.gov (United States)

    Lee, Hee Uk; Kim, Hyunsoo; Chun, Kyoung-Yong; Kwon, Cheong Hoon; Lima, Márcio D.; Baughman, Ray H.; Kim, Seon Jeong

    2016-07-01

    Most polydiacetylenes (PDAs) have been studied as chromatic sensors or temperature indicators because of their phase transition that is accompanied by a color change from blue to red. Here, we focus on the structural change based on the polydiacetylene phase transition for a temperature-responsive tensile actuator at low temperature using a copolymer composed of PDA and pluronic in a multi-walled carbon nanotube (MWCNT) coiled yarn. In this paper, we do not focus on the general color change phenomenon of PDA. We demonstrate that the volume change of PDA in the MWCNT coiled yarn provides ˜180% tensile strain at low temperature (˜53 °C). Insertion of the pluronic copolymer into the coiled yarn composed of PDA and MWCNT caused the tensile actuation temperature to decrease by ˜6 °C (with tensile actuation of ˜230%) compared to an actuator without pluronic copolymer. Furthermore, we could verify that the large tensile actuation was also predominantly affected by the melting of the nonpolymerized diacetylene (DA) monomer and the pluronic copolymer. MWCNT coiled yarn actuators with PDA-pluronic copolymer can be easily prepared, have a large tensile actuation, and are actuated at low temperature. It could be used as temperature indicators in the food, drugs, and medical fields.

  10. Modeling Endovascular Coils as Heterogeneous Porous Media

    Science.gov (United States)

    Yadollahi Farsani, H.; Herrmann, M.; Chong, B.; Frakes, D.

    2016-12-01

    Minimally invasive surgeries are the stat-of-the-art treatments for many pathologies. Treating brain aneurysms is no exception; invasive neurovascular clipping is no longer the only option and endovascular coiling has introduced itself as the most common treatment. Coiling isolates the aneurysm from blood circulation by promoting thrombosis within the aneurysm. One approach to studying intra-aneurysmal hemodynamics consists of virtually deploying finite element coil models and then performing computational fluid dynamics. However, this approach is often computationally expensive and requires extensive resources to perform. The porous medium approach has been considered as an alternative to the conventional coil modeling approach because it lessens the complexities of computational fluid dynamics simulations by reducing the number of mesh elements needed to discretize the domain. There have been a limited number of attempts at treating the endovascular coils as homogeneous porous media. However, the heterogeneity associated with coil configurations requires a more accurately defined porous medium in which the porosity and permeability change throughout the domain. We implemented this approach by introducing a lattice of sample volumes and utilizing techniques available in the field of interactive computer graphics. We observed that the introduction of the heterogeneity assumption was associated with significant changes in simulated aneurysmal flow velocities as compared to the homogeneous assumption case. Moreover, as the sample volume size was decreased, the flow velocities approached an asymptotical value, showing the importance of the sample volume size selection. These results demonstrate that the homogeneous assumption for porous media that are inherently heterogeneous can lead to considerable errors. Additionally, this modeling approach allowed us to simulate post-treatment flows without considering the explicit geometry of a deployed endovascular coil mass

  11. Modeling the Insertion Mechanics of Flexible Neural Probes Coated with Sacrificial Polymers for Optimizing Probe Design

    Science.gov (United States)

    Singh, Sagar; Lo, Meng-Chen; Damodaran, Vinod B.; Kaplan, Hilton M.; Kohn, Joachim; Zahn, Jeffrey D.; Shreiber, David I.

    2016-01-01

    Single-unit recording neural probes have significant advantages towards improving signal-to-noise ratio and specificity for signal acquisition in brain-to-computer interface devices. Long-term effectiveness is unfortunately limited by the chronic injury response, which has been linked to the mechanical mismatch between rigid probes and compliant brain tissue. Small, flexible microelectrodes may overcome this limitation, but insertion of these probes without buckling requires supporting elements such as a stiff coating with a biodegradable polymer. For these coated probes, there is a design trade-off between the potential for successful insertion into brain tissue and the degree of trauma generated by the insertion. The objective of this study was to develop and validate a finite element model (FEM) to simulate insertion of coated neural probes of varying dimensions and material properties into brain tissue. Simulations were performed to predict the buckling and insertion forces during insertion of coated probes into a tissue phantom with material properties of brain. The simulations were validated with parallel experimental studies where probes were inserted into agarose tissue phantom, ex vivo chick embryonic brain tissue, and ex vivo rat brain tissue. Experiments were performed with uncoated copper wire and both uncoated and coated SU-8 photoresist and Parylene C probes. Model predictions were found to strongly agree with experimental results (probe length were the most important features in influencing insertion potential. The model also revealed the effects of manufacturing flaws on insertion potential. PMID:26959021

  12. Allosteric effects in coiled-coil proteins folding and lanthanide-ion binding.

    Science.gov (United States)

    Samiappan, Manickasundaram; Alasibi, Samaa; Cohen-Luria, Rivka; Shanzer, Abraham; Ashkenasy, Gonen

    2012-10-07

    Peptide sequences modified with lanthanide-chelating groups at their N-termini, or at their lysine side chains, were synthesized, and new Ln(III) complexes were characterized. We show that partial folding of the conjugates to form trimer coiled coil structures induces coordination of lanthanides to the ligand, which in turn further stabilizes the 3D structure.

  13. Folding Topology of a Short Coiled-Coil Peptide Structure Templated by an Oligonucleotide Triplex

    DEFF Research Database (Denmark)

    Lou, Chenguang; Christensen, Niels Johan; Martos Maldonado, Manuel Cristo

    2017-01-01

    The rational design of a well-defined protein-like tertiary structure formed by small peptide building blocks is still a formidable challenge. By using peptide-oligonucleotide conjugates (POC) as building blocks, we present the self-assembly of miniature coiled-coil α-helical peptides guided...

  14. Antiparallel Four-Stranded Coiled Coil Specified by a 3-3-1 Hyrdrophobic Heptad Repeat

    Energy Technology Data Exchange (ETDEWEB)

    Deng,Y.; Liu, J.; Zheng, Q.; Eliezer, D.; Kallenbach, N.; Lu, M.

    2006-01-01

    Coiled-coil sequences in proteins commonly share a seven-amino acid repeat with nonpolar side chains at the first (a) and fourth (d) positions. We investigate here the role of a 3-3-1 hydrophobic repeat containing nonpolar amino acids at the a, d, and g positions in determining the structures of coiled coils using mutants of the GCN4 leucine zipper dimerization domain. When three charged residues at the g positions in the parental sequence are replaced by nonpolar alanine or valine side chains, stable four-helix structures result. The X-ray crystal structures of the tetramers reveal antiparallel, four-stranded coiled coils in which the a, d, and g side chains interlock in a combination of knobs-into-knobs and knobs-into-holes packing. Interfacial interactions in a coiled coil can therefore be prescribed by hydrophobic-polar patterns beyond the canonical 3-4 heptad repeat. The results suggest that the conserved, charged residues at the g positions in the GCN4 leucine zipper can impart a negative design element to disfavor thermodynamically more stable, antiparallel tetramers.

  15. Golgi coiled-coil proteins contain multiple binding sites for Rab family G proteins

    NARCIS (Netherlands)

    Sinka, Rita; Gillingham, Alison K.; Kondylis, Vangelis; Munro, Sean

    2008-01-01

    Vesicles and other carriers destined for the Golgi apparatus must be guided to the correct cisternae. Golgins, long coiled-coil proteins that localize to particular Golgi subdomains via their C termini, are candidate regulators of vesicle sorting. In this study, we report that the GRIP domain

  16. Superconducting Quadrupole for the ISR High Luminosity insertion:end view

    CERN Multimedia

    1977-01-01

    Connection end view of the prototype quadrupole before insertion of the inner vacuum chamber with inbedded 6-pole windings. The main components of the structure can be seen: (from inside outwards) the superconducting quadrupole coils surrounded by glass epoxy bandage rings and stainless steel spacers, the low-carbon steel yoke quadrants and the aluminium alloy shrinking rings. See also photos 7702690X, 7702307, 7702308, 7812604X.

  17. Prototype Superconducting Quadrupole for the ISR high-luminosity (low beta)insertion:end view.

    CERN Multimedia

    CERN PhotoLab

    1977-01-01

    In this picture, taken before the insertion of the inner vacuum chamber with inbedded 6-pole superconducting windings, one can see the main components of the magnet structure: (from inside outwards) the superconducting quadrupole coils surronded by glass epoxy bandage rings and stainless steel spacers, the low-carbon steel yoke quadrants and the aluminium alloy shrinking rings. See also photos 7702307, 7702688X, 7702690X.

  18. Analysis and experimental study of wireless power transfer with HTS coil and copper coil as the intermediate resonators system

    Energy Technology Data Exchange (ETDEWEB)

    Wang, Xiufang [School of Electrical Engineering, Southwest Jiaotong University, Chengdu, Sichuan 610031 (China); School of Physics and Technology, Southwest Jiaotong University, Chengdu, Sichuan 610031 (China); Nie, Xinyi [School of Electrical Engineering, Southwest Jiaotong University, Chengdu, Sichuan 610031 (China); Liang, Yilang [School of Physics and Technology, Southwest Jiaotong University, Chengdu, Sichuan 610031 (China); Lu, Falong [School of Electrical Engineering, Southwest Jiaotong University, Chengdu, Sichuan 610031 (China); Yan, Zhongming, E-mail: wangxiufanghappy@163.com [School of Electrical Engineering, Southwest Jiaotong University, Chengdu, Sichuan 610031 (China); Wang, Yu [School of Electrical Engineering, Southwest Jiaotong University, Chengdu, Sichuan 610031 (China)

    2017-01-15

    Highlights: • We investigated a kind of system architecture with three coils which the repeater is copper coil or HTS coil. • We simulated the different repeater system and obtained the magnetic field distribution at different distance. • We used helical coil instead of pancake coil which does not use capacitors. • HTS intermediate coil has significant effect on improving the transmission efficiency and lengthening transmission distance than copper intermediate coil. - Abstract: Intermediate resonator (repeater) between transmitter and receiver can significantly increase the distance of wireless power transfer (WPT) and the efficiency of wireless power transfer. The wireless power transfer via strongly coupled magnetic resonances with an high temperature superconducting (HTS) coil and copper coil as intermediate resonators was presented in this paper. The electromagnetic experiment system under different conditions with different repeating coils were simulated by finite element software. The spatial distribution patterns of magnetic induction intensity at different distances were plotted. In this paper, we examined transfer characteristics with HTS repeating coil and copper repeating coil at 77 K and 300 K, respectively. Simulation and experimental results show that HTS and copper repeating coil can effectively enhance the space magnetic induction intensity, which has significant effect on improving the transmission efficiency and lengthening transmission distance. We found that the efficiency and the distance of wireless power transfer system with an HTS coil as repeater is much higher by using of copper coil as repeater.

  19. Correlated atomic wires on substrates. II. Application to Hubbard wires

    Science.gov (United States)

    Abdelwahab, Anas; Jeckelmann, Eric; Hohenadler, Martin

    2017-07-01

    In the first part of our theoretical study of correlated atomic wires on substrates, we introduced lattice models for a one-dimensional quantum wire on a three-dimensional substrate and their approximation by quasi-one-dimensional effective ladder models [Abdelwahab et al., preceding paper, Phys. Rev. B 96, 035445 (2017), 10.1103/PhysRevB.96.035445]. In this second part, we apply this approach to the case of a correlated wire with a Hubbard-type electron-electron repulsion deposited on an insulating substrate. The ground-state and spectral properties are investigated numerically using the density-matrix renormalization group method and quantum Monte Carlo simulations. As a function of the model parameters, we observe various phases with quasi-one-dimensional low-energy excitations localized in the wire, namely, paramagnetic Mott insulators, Luttinger liquids, and spin-1 /2 Heisenberg chains. The validity of the effective ladder models is assessed for selected parameters by studying the dependence of results on the number of legs and comparing to the full three-dimensional model. We find that narrow ladder models accurately reproduce the quasi-one-dimensional excitations of the full three-dimensional model but predict only qualitatively whether excitations are localized around the wire or delocalized in the three-dimensional substrate.

  20. Performance Characterization of Micromachined Inductive Suspensions Based on 3D Wire-Bonded Microcoils

    Directory of Open Access Journals (Sweden)

    Zhiqiu Lu

    2014-12-01

    Full Text Available We present a comprehensive experimental investigation of a micromachined inductive suspension (MIS based on 3D wire-bonded microcoils. A theoretical model has been developed to predict the levitation height of the disc-shaped proof mass (PM, which has good agreement with the experimental results. The 3D MIS consists of two coaxial wire-bonded coils, the inner coil being used for levitation, while the outer coil for the stabilization of the PM. The levitation behavior is mapped with respect to the input parameters of the excitation currents applied to the levitation and stabilization coil, respectively: amplitude and frequency. At the same time, the levitation is investigated with respect to various thickness values (12.5 to 50 μm and two materials (Al and Cu of the proof mass. An important characteristic of an MIS, which determines its suitability for various applications, such as, e.g., micro-motors, is the dynamics in the lateral direction. We experimentally study the lateral stabilization force acting on the PM as a function of the linear displacement. The analysis of this dependency allows us to define a transition between stable and unstable levitation behavior. From an energetic point of view, this transition corresponds to the local maximum of the MIS potential energy. 2D simulations of the potential energy help us predict the location of this maximum, which is proven to be in good agreement with the experiment. Additionally, we map the temperature distribution for the coils, as well as for the PM levitated at 120 μm, which confirms the significant reduction of the heat dissipation in the MIS based on 3D microcoils compared to the planar topology.

  1. Incidental finding of a left over guide wire on a positron emission tomography

    Energy Technology Data Exchange (ETDEWEB)

    Yap, Kok Hooi; Lee, Phong Teck; Buch, Mamta; Rammohan, Kandadai Seshadri

    2012-12-15

    The Seldinger technique is commonly used cannulate vessels for radiographical procedures. Loss of a guide wire into the circulation is a rare and preventable complication. It is often noticed by chance during routine radiographs. However, there is a lack of reported cases of incidental fin dings of leftover guide wire on a PET scan. An intravascular foreign body should be retrieved as soon as the diagnosis is made, to prevent complications such as embolisation or vascular damage by fractured wires. Interventional radiology is the method of choice for retrieval. We report a rare case of the coincidental finding of a lost guide wire on a PET scan. A 37 year old man presented with psychotic episodes, thigh weakness, weight gain, increased appetite and leg cramps. He was subsequently diagnosed with cushing syndrome secondary to ectopic adrenocorticotropic secretion from a right lung tumour. He subsequently underwent a staging positron emission tomography (PET) scan. The lung tumour had no uptake on PET bit had increased activity uptake on octreotide scanning. These appearances were suggestive of with carcinoid tumour. The PET scan also revealed an incidental finding of a leftover guide wire used during peripheral inserted central catheter (PICC) recently. The wire extended from right atrium to inferior vena cava. It also showed a high uptake in the adrenal glands, indicating hyperplasia, which was most likely due to adrenocorticotropic hormone stimulation. He underwent a percutaneous wire retrieval via the right femoral vein in a cardiac catheterisation laboratory and was transferred to a thoracic surgical unit for lung tumor resection.

  2. Evaluation of feasibility of 1.5 Tesla prostate MRI using body coil RF transmit in a patient with an implanted vagus nerve stimulator.

    Science.gov (United States)

    Favazza, Christopher P; Edmonson, Heidi A; Ma, Chi; Shu, Yunhong; Felmlee, Joel P; Watson, Robert E; Gorny, Krzysztof R

    2017-09-07

    To assess risks of RF-heating of a vagus nerve stimulator (VNS) during 1.5 T prostate MRI using body coil transmit and to compare these risks with those associated with MRI head exams using a transmit/receive head coil. Spatial distributions of radio-frequency (RF) B1 fields generated by transmit/receive (T/R) body and head coils were empirically assessed along the long axis of a 1.5 T MRI scanner bore. Measurements were obtained along the center axis of the scanner and laterally offset by 15 cm (body coil) and 7 cm (head coil). RF-field measurements were supplemented with direct measurements of RF-heating of 15 cm long copper wires affixed to and submerged in the "neck" region of the gelled saline-filled (sodium chloride and polyacrylic acid) "head-and-torso" phantom. Temperature elevations at the lead tips were measured using fiber-optic thermometers with the phantom positioned at systematically increased distances from the scanner isocenter. B1 field measurements demonstrated greater than 10 dB reduction in RF power at distances beyond 28 cm and 24 cm from isocenter for body and head coil, respectively. Moreover, RF power from body coil transmit at distances greater than 32 cm from isocenter was found to be lower than from the RF power from head coil transmit measured at locations adjacent to the coil array at its opening. Correspondingly, maximum temperature elevations at the tips of the copper wires decreased with increasing distance from isocenter - from 7.4°C at 0 cm to no appreciable heating at locations beyond 40 cm. For the particular scanner model evaluated in this study, positioning an implanted VNS farther than 32 cm from isocenter (configuration achievable for prostate exams) can reduce risks of RF-heating resulting from the body coil transmit to those associated with using a T/R head coil. © 2017 American Association of Physicists in Medicine.

  3. Diagnostics of underwater electrical wire explosion through a time- and space-resolved hard x-ray source.

    Science.gov (United States)

    Sheftman, D; Shafer, D; Efimov, S; Gruzinsky, K; Gleizer, S; Krasik, Ya E

    2012-10-01

    A time- and space-resolved hard x-ray source was developed as a diagnostic tool for imaging underwater exploding wires. A ~4 ns width pulse of hard x-rays with energies of up to 100 keV was obtained from the discharge in a vacuum diode consisting of point-shaped tungsten electrodes. To improve contrast and image quality, an external pulsed magnetic field produced by Helmholtz coils was used. High resolution x-ray images of an underwater exploding wire were obtained using a sensitive x-ray CCD detector, and were compared to optical fast framing images. Future developments and application of this diagnostic technique are discussed.

  4. Expanding Endovascular Therapy of Very Small Ruptured Aneurysms with the 1.5-mm Coil

    Science.gov (United States)

    Nguyen, Thanh N.; Masoud, Hesham; Tarlov, Nicholas; Holsapple, James; Chin, Lawrence S.; Norbash, Alexander M.

    2015-01-01

    Background Very small ruptured aneurysms (≤3 mm) demonstrate a significant risk for procedural rupture with endovascular therapy. Since 2007, 1.5-mm-diameter coils have been available (Micrus, Microvention, and ev3), allowing neurointerventionalists the opportunity to offer patients with very small aneurysms endovascular treatment. In this study, we review the clinical and angiographic outcome of patients with very small ruptured aneurysms treated with the 1.5-mm coil. Methods This is a retrospective cohort study in which we examined consecutive ruptured very small aneurysms treated with coil embolization at a single institution. The longest linear aneurysm was recorded, even if the first coil was sized to a smaller transverse diameter. Very small aneurysms were defined as ≤3 mm. Descriptive results are presented. Results From July 2007 to March 2015, 81 aneurysms were treated acutely with coils in 78 patients presenting with subarachnoid hemorrhage. There were 5 patients with 3-mm aneurysms, of which the transverse diameter was ≤2 mm in 3 patients. In all 5 patients, a balloon was placed for hemostatic prophylaxis in case of rupture, and a single 1.5-mm coil was inserted for aneurysm treatment without complication. Complete aneurysm occlusion was achieved in 1 patient, residual neck in 2, and residual aneurysm in 2 patients. Aneurysm recanalization was present in 2 patients with an anterior communicating artery aneurysm; a recoiling attempt was unsuccessful in 1 of these 2 patients due to inadvertent displacement and distal coil embolization, but subsequent surgical clipping was successful. Another patient was retreated by surgical clipping for a residual wide-neck carotid terminus aneurysm. One patient died of ventriculitis 3 weeks after presentation; all 4 other patients had an excellent outcome with no rebleed at follow-up (mean 21 months, range 1-62). Conclusion The advent of the 1.5-mm coil may be used in the endovascular treatment of patients with very

  5. Critical current studies of a HTS rectangular coil

    Energy Technology Data Exchange (ETDEWEB)

    Zhong, Z. [Department of Engineering, University of Cambridge (United Kingdom); Chudy, M., E-mail: Michal.chudy@stuba.sk [Graduate School of Technology Management, University of Pretoria (South Africa); Institute of Power and Applied Electrical Engineering, Slovak University of Technology in Bratislava (Slovakia); Ruiz, H.S. [Department of Engineering, University of Leicester, Leicester LE1 7RH (United Kingdom); Zhang, X.; Coombs, T. [Department of Engineering, University of Cambridge (United Kingdom)

    2017-05-15

    Highlights: • Unique square pancake coil was manufactured. • Measurements in relatively high magnetic field were performed. • Different sections of the coil were characterized. • Parts of the coil which are limiting critical current were identified. - Abstract: Nowadays, superconducting high field magnets are used in numerous applications due to their superior properties. High temperature superconductors (HTS) are usually used for production of circular pancake or racetrack coils. However different geometries of HTS coils might be required for some specific applications. In this study, the HTS coil wound on a rectangular frame was fully characterized in homogeneous DC background field. The study contains measurements of critical current angular dependencies. The critical current of the entire coil and two selected strands under different magnitudes and orientations of external magnetic fields are measured. The critical regions of the coil in different angular regimes are determined. This study brings better understanding of the in- field performance of HTS coils wound on frames with right-angles.

  6. Improving Coil Designs for the HSX Stellarator with FOCUS

    Science.gov (United States)

    Kruger, Thomas; Zhu, Caoxiang; Bader, Aaron; Singh, Luquant; Anderson, David

    2017-10-01

    We use the FOCUS code to generate improved coil sets for the HSX stellarator. FOCUS produces curves in 3D space to best reproduce a target plasma equilibrium. Unlike similar codes, the curves in FOCUS are not constrained to lie on a user-defined 2D surface. Therefore FOCUS can inherently solve problems such as determining the optimum coil-plasma distance for a given equilibrium. By adjusting the relative weights between a) the match to the plasma boundary, and b) the average coil length. We present the results from FOCUS where we attempt to improve the coil set by moving coils further away to reduce coil ripple, decreasing the number of coils to improve accessibility, and better matching the target plasma surface. We also present results of alternative coil designs with helical and saddle coils. Work supported by the US DOE under Grant DE-FG02-93ER54222 and UW Sorden account 233PRJ65ZM.

  7. Damping insert materials for settling chambers of supersonic wind tunnels

    Science.gov (United States)

    Wu, Jie; Radespiel, Rolf

    2017-03-01

    This study describes the application of a novel damping insert material for reducing the flow fluctuations in a tandem nozzle supersonic wind tunnel. This new damping material is composed of multi-layer stainless steel wired meshes. The influences of the multi-layer mesh, such as the quantity of the mesh layer and the installed location in the settling chamber, to the freestream quality have been investigated. A Pitot probe instrumented with a Kulite pressure sensor and a hot-wire probe are employed to monitor the flow fluctuation in the test section of the wind tunnel. Thereafter, a combined modal analysis is applied for the disturbance qualification. Additionally, the transient Mach number in the test section is measured. The disturbance qualification indicates that the multi-layer mesh performs well in providing reduction of vorticity reduction and acoustic fluctuations. Comparable flow quality of the freestream was also obtained using a combination of flexible damping materials. However, the life-span of the new damping materials is much longer. The time transient of the Mach number measured in the test section indicates that the mean flow is rather constant over run time. Furthermore, the time-averaged pressure along the settling chamber is recorded and it shows the distribution of pressure drop by settling chamber inserts.

  8. Comparison of four techniques of nasogastric tube insertion in anaesthetised, intubated patients: A randomized controlled trial

    Directory of Open Access Journals (Sweden)

    Mohan Chandra Mandal

    2014-01-01

    Full Text Available Background and Aims: Insertion of nasogastric tubes (NGTs in anaesthetised, intubated patients with a conventional method is sometimes difficult. Different techniques of NGT insertion have been tried with varying degree of success. The aim of this prospective, randomised, open-label study was to evaluate three modified techniques of NGT insertion comparing with the conventional method in respect of success rate, time taken for insertion and the adverse events. Methods: In the operation theatre of general surgery, the patients were randomly allocated into four groups: Group C (control group, n = 54, Group W (ureteral guide wire group, n = 54, Group F (neck flexion with lateral pressure, n = 54 and Group R (reverse Sellick′s manoeuvre, n = 54. The number of attempts for successful NGT insertion, time taken for insertion and adverse events were noted. Results: All the three modified techniques were found more successful than the conventional method on the first attempt. The least time taken for insertion was noted in the reverse Sellick′s method. However, on intergroup analysis, neck flexion and reverse Sellick′s methods were comparable but significantly faster than the other two methods with respect to time taken for insertion. Conclusion: Reverse Sellick′s manoeuver, neck flexion with lateral neck pressure and guide wire-assisted techniques are all better alternatives to the conventional method for successful, quick and reliable NGT insertion with permissible adverse events in anaesthetised, intubated adult patients. Further studies after eliminating major limitations of the present study are warranted to establish the superiority of any one of these modified techniques.

  9. Wire chambers revisited.

    Science.gov (United States)

    Ott, R J

    1993-04-01

    Detectors used for radioisotope imaging have, historically, been based on scintillating crystal/photomultiplier combinations in various forms. From the rectilinear scanner through to modern gamma cameras and positron cameras, the basic technology has remained much the same. Efforts to overcome the limitations of this form of technology have foundered on the inability to reproduce the required sensitivity, spatial resolution and sensitive area at acceptable cost. Multiwire proportional chambers (MWPCs) have long been used as position-sensitive charged particle detectors in nuclear and high-energy physics. MWPCs are large-area gas-filled ionisation chambers in which large arrays of fine wires are used to measure the position of ionisation produced in the gas by the passage of charged particles. The important properties of MWPCs are high-spatial-resolution, large-area, high-count-rate performance at low cost. For research applications, detectors several metres square have been built and small-area detectors have a charged particle resolution of 0.4 mm at a count rate of several million per second. Modification is required to MWPCs for nuclear medicine imaging. As gamma rays or X-rays cannot be detected directly, they must be converted into photo- or Compton scatter electrons. Photon-electron conversion requires the use of high atomic number materials in the body of the chamber. Pressurised xenon is the most useful form of "gas only" photon-electron convertor and has been used successfully in a gamma camera for the detection of gamma rays at energies below 100 keV. This camera has been developed specifically for high-count-rate first-pass cardiac imaging. This high-pressure xenon gas MWPC is the key to a highly competitive system which can outperform scintillator-based systems. The count rate performance is close to a million counts per second and the intrinsic spatial resolution is better than the best scintillator-based camera. The MWPC camera produces quantitative

  10. Gas turbine vane cooling air insert

    Energy Technology Data Exchange (ETDEWEB)

    North, W.E.; Hultgren, K.G.; Dishman, C.D.; Van Heusden, G.S.

    1992-09-08

    This patent describes a gas turbine. It comprises turbine vanes, each of the vanes supplied with cooling air and having: an airfoil portion forming a first cavity having an insert disposed therein for directing the flow of the cooling air, the insert having first and second insert ends; a shroud portion from which the airfoil portion extends, the insert attached to the shroud portion at the first insert end; an insert extension extending through a portion of the insert and extending beyond the first insert end, the insert extension and the insert forming an annular gap therebetween separating the insert from the insert extension; a plate covering at least a portion of the shroud, the plate having a first hole formed therein through which the insert extension extends; and at least a first seal extending between the insert extension and the insert, and sealing the annular gap therebetween. This patent also describes a method of making a gas turbine. It comprises welding a first tubular insert adjacent its first end to a vane outer shroud; partially inserting a second tubular insert into the first tubular member and attaching the second tubular insert thereto; placing a plate having a hole formed therein on the outer shroud so that the hole surrounds the second tubular insert; and attaching the second tubular insert to the plate by placing a first seal between the first and second tubular inserts and attaching the first seal to each of the first and second tubular inserts, and placing a second seal between the second tubular insert and the plate and welding the second seal to the second tubular insert and the plate.

  11. Coupled wave model for large magnet coils

    Science.gov (United States)

    Gabriel, G. J.

    1980-01-01

    A wave coupled model based on field theory is evolved for analysis of fast electromagnetic transients on superconducting coils. It is expected to play a useful role in the design of protection methods against damage due to high voltages or any adverse effects that might arise from unintentional transients. The significant parameters of the coil are identified to be the turn to turn wave coupling coefficients and the travel time of an electromagnetic disturbance around a single turn. Unlike circuit theoretic inductor, the coil response evolves in discrete steps having durations equal to this travel time. It is during such intervals that high voltages are likely to occur. The model also bridges the gap between the low and high ends of the frequency spectrum.

  12. Determination of Coil Inductances Cylindrical Iron Nucleus

    Directory of Open Access Journals (Sweden)

    Azeddine Mazouz

    2014-03-01

    Full Text Available The paper describes the investigation and development of a structure and performance characteristics of a coil iron nucleus cylindrical (C.I.N.C. The coil iron nucleus cylindrical is a nonlinear electro radio in which the moving of the nucleus in a sense or in other causes change in inductance and can reach extreme values at the superposition of nucleus and coil centers. The variation of the inductance and the degree of freedom of movement of the nucleus can lead to a device with electromechanical conversion The aim of this paper is the determination and visualization of self inductance and mutual of the (C.I.N.C based on geometric dimensions and the displacement of the nucleus.  

  13. Acoustic rainbow trapping by coiling up space

    KAUST Repository

    Ni, Xu

    2014-11-13

    We numerically realize the acoustic rainbow trapping effect by tapping an air waveguide with space-coiling metamaterials. Due to the high refractive-index of the space-coiling metamaterials, our device is more compact compared to the reported trapped-rainbow devices. A numerical model utilizing effective parameters is also calculated, whose results are consistent well with the direct numerical simulation of space-coiling structure. Moreover, such device with the capability of dropping different frequency components of a broadband incident temporal acoustic signal into different channels can function as an acoustic wavelength division de-multiplexer. These results may have potential applications in acoustic device design such as an acoustic filter and an artificial cochlea.

  14. [Intracavitary electrocardiogram during the insertion of peripherally inserted central catheters].

    Science.gov (United States)

    Ortiz-Miluy, Gloria; Sánchez-Guerra, Carmen

    2013-01-01

    To evaluate the applicability, feasibility and accuracy of the IC-ECG with column of saline technique for verifying the final tip position of peripherally inserted central catheters (PICC) by specialist nurses. A total of 99 consecutive PICC were inserted. Patients with no superficial ECG P wave, atrial fibrillation, or a pacemaker were excluded. The IC-ECG technique was performed on 84 patients. A chest x-ray was performed after insertion in all cases, in order to compare images with IC-ECG. The technique showed an applicability of 84.4%, an feasibility of 88%, and an accuracy of 87.8%. The IC-ECG technique for verification of catheter PICC tip locations with column of saline is easy to apply, is cost-effective, is achievable by nurses, and does not involve any risk for patients. The technique involves a learning curve, and it must be performed by qualified health care professionals. The technique is performed during the insertion of the catheter, so verification of the tip is made in situ. It reduces future re-insertions due to wrong positioning of the tip. Copyright © 2013 Elsevier España, S.L. All rights reserved.

  15. Plasma arc torch with coaxial wire feed

    Science.gov (United States)

    Hooper, Frederick M

    2002-01-01

    A plasma arc welding apparatus having a coaxial wire feed. The apparatus includes a plasma arc welding torch, a wire guide disposed coaxially inside of the plasma arc welding torch, and a hollow non-consumable electrode. The coaxial wire guide feeds non-electrified filler wire through the tip of the hollow non-consumable electrode during plasma arc welding. Non-electrified filler wires as small as 0.010 inches can be used. This invention allows precision control of the positioning and feeding of the filler wire during plasma arc welding. Since the non-electrified filler wire is fed coaxially through the center of the plasma arc torch's electrode and nozzle, the wire is automatically aimed at the optimum point in the weld zone. Therefore, there is no need for additional equipment to position and feed the filler wire from the side before or during welding.

  16. Ocular dangers of fencing wire.

    Science.gov (United States)

    McAllum, P; Barnes, R; Dickson, J

    2001-07-27

    To invesitgate the incidence and severity of penetrating eye injuries caused by fencing wire in the Waikato region. We reviewed the case notes for all penetrating eye injuries treated at Waikato Hospital during the past six years. Parameters recorded were patient age and sex, mechanism of injury, initial visual acuity, characteristics of injury, surgery performed and final visual outcome. The incidence of penetrating eye injuries in the Waikato region was 3.8 per 100,000 per year, based on an estimated catchment population of 350,000. We found fencing wire to be the third most common cause of penetrating eye injury, accounting for 8.8% of injuries, behind motor vehicle accidents and hammering which accounted for 26.3% and 20.0% of injuries, respectively. The fencing wire injuries involved men exclusively, with an average age of 41.7 years. Fencing wire injuries had worse presenting visual acuity than other injuries, involved the posterior segment of the eye more frequently and were more likely to develop bacterial endophthalmitis. They also underwent more surgical procedures and were more commonly associated with a poor visual outcome. Fencing wire is an important cause of visual loss in the Waikato region. We hope to raise awareness of its potential ocular dangers and to promote the use of appropriate eye protection.

  17. ADC's Insertion Devices and Magnetic Measurement Systems Capabilities

    Science.gov (United States)

    Deyhim, A.; Kulesza, J.

    2013-03-01

    In this paper Advance Design Consulting USA, Inc. (ADC) will discuss ADC's major improved capabilities for building Wiggler Insertion Devices, Undulator Planar Devices, Elliptical Polarizing Undulators (EPU), In-Vacuum Undulators (IVU), Cryogenically Cooled in-vacuum Undulators (CPMU), Super Conductive Undulator, and Insertion Device Magnetic Measurement Systems. ADC has designed, built and delivered Insertion Devices and Magnetic Measurement Systems to such facilities as MAX-lab (two EPUs, a Planar, and Measurement System), ALBA and ASP (Wigglers), BNL (CPMU), SSRF (two IVUs and a Measurement System), PAL (one IVU and Measurement System), NSRRC (one 4m EPU), and SRC (Planar and EPU). ADC's magnetic field measurement system is a sophisticated and sensitive machine for the measurement of magnetic fields in undulators (Planar and EPU), wigglers and in-vacuum ID units. The magnetic fields are measured using 3 axis hall-effect probes, mounted orthogonally, to a thin wand. The wand is mounted to a carriage that rides on vacuum air bearings. The base is granite. A flip coil is provided on two vertical towers with X, Y and Theta axes. Special software is provided to assist in homing, movement, and data collection and analysis.

  18. R&D for a single-layer $Nb_{3}Sn$ common coil dipole using the react-and-wind fabrication technique

    CERN Document Server

    Ambrosio, G; Barzi, E; Bauer, P; Chichili, D R; Ewald, K D; Fehér, S; Imbasciati, L; Kashikhin, V V; Limon, P J; Litvinenko, L; Novitski, I; Rey, J M; Scanlan, R M; Yadav, S; Yamada, R; Zlobin, A V

    2002-01-01

    A dipole magnet based on the common coil design, using prereacted Nb /sub 3/Sn superconductor, is under development at Fermilab, for a future Very Large Hadron Collider. This magnet has some innovative design and technological features such as single layer coils, a 22 mm wide 60-strand Rutherford type cable and stainless steel collars reinforced by horizontal bridges inserted between coil blocks. Both left and right coils are wound simultaneously into the collar structure and then impregnated with epoxy. In order to optimize the design and fabrication techniques an R&D program is underway. The production of cables with the required characteristics was shown possible. Collar laminations were produced, assembled and tested in order to check the effectiveness of the bridges and the validity of the mechanical design. A mechanical model consisting in a 165 mm long section of the magnet straight section was assembled and tested. This paper summarizes the status of the program, and reports the results of fabrica...

  19. Superconducting Coil Winding Machine Control System

    Energy Technology Data Exchange (ETDEWEB)

    Nogiec, J. M. [Fermilab; Kotelnikov, S. [Fermilab; Makulski, A. [Fermilab; Walbridge, D. [Fermilab; Trombly-Freytag, K. [Fermilab

    2016-10-05

    The Spirex coil winding machine is used at Fermilab to build coils for superconducting magnets. Recently this ma-chine was equipped with a new control system, which al-lows operation from both a computer and a portable remote control unit. This control system is distributed between three layers, implemented on a PC, real-time target, and FPGA, providing respectively HMI, operational logic and direct controls. The system controls motion of all mechan-ical components and regulates the cable tension. Safety is ensured by a failsafe, redundant system.

  20. Multiple coil closure of isolated aortopulmonary collateral

    Directory of Open Access Journals (Sweden)

    Padhi Sumanta

    2010-01-01

    Full Text Available A 7-month-old girl was diagnosed to have large aortopulmonary collateral during evaluation for congestive heart failure. There was no other evidence of cardiopulmonary disease. The collateral was successfully closed with multiple coils delivered sequentially. We describe the issues associated during closure of the aortopulmonary collateral in this case. To the best of our knowledge, this is the first reported case of large aortopulmonary collateral presenting with heart failure in an otherwise structurally normal heart that was closed successfully with multiple coils delivered sequentially.

  1. Self-assembling segmented coiled tubing

    Energy Technology Data Exchange (ETDEWEB)

    Raymond, David W.

    2016-09-27

    Self-assembling segmented coiled tubing is a concept that allows the strength of thick-wall rigid pipe, and the flexibility of thin-wall tubing, to be realized in a single design. The primary use is for a drillstring tubular, but it has potential for other applications requiring transmission of mechanical loads (forces and torques) through an initially coiled tubular. The concept uses a spring-loaded spherical `ball-and-socket` type joint to interconnect two or more short, rigid segments of pipe. Use of an optional snap ring allows the joint to be permanently made, in a `self-assembling` manner.

  2. A new type of coil structure called pan-shaped coil of wireless charging system based on magnetic resonance

    Science.gov (United States)

    Yue, Z. K.; Liu, Z. Z.; Hou, Y. J.; Zeng, H.; Liang, L. H.; Cui, S.

    2017-11-01

    The problem that misalignment between the transmitting coil and the receiving coil significantly impairs the transmission power and efficiency of the system has been attached more and more attention. In order to improve the uniformity of the magnetic field between the two coils to solve this problem, a new type of coil called pan-shaped coil is proposed. Three-dimension simulation models of the planar-core coil and the pan-shaped coil are established using Ansoft Maxwell software. The coupling coefficient between the transmitting coil and the receiving coil is obtained by simulating the magnetic field with the receiving coil misalignment or not. And the maximum percentage difference strength along the radial direction which is defined as the magnetic field uniformity factor is calculated. According to the simulation results of the two kinds of coil structures, it is found that the new type of coil structure can obviously improve the uniformity of the magnetic field, coupling coefficient and power transmission properties between the transmitting coil and the receiving coil.

  3. Research and development of MRI surface coil for TMJ MR imaging; Modulated Helmholtz surface coil

    Energy Technology Data Exchange (ETDEWEB)

    Kukimoto, Yoshiaki; Kukimoto, Kyoko (Kameda General Hospital, Kamogawa, Chiba (Japan)); Shirakawa, Toyomi

    1989-12-01

    Internal derangements of the temporomandibular joint (TMJ) are a major cause of jaw pain and dysfunction as well as other related clinical symptoms. TMJ diagnosis is the abnormal position and appearance of the disk. Most X-ray-based methods are useful for evaluating bony abnormalities, but their reduced soft-tissue contrast often makes the diagnostic evaluation of TMJ disorders difficult. Magnetic resonance (MR) imaging is a very recent addition to the medical diagnostic of TMJ diseases. MR imaging can produce high-quality tomographic images of greater soft-tissue contrast without ionizing radiation or known biological hazards. MR system was circular type Simens Magnetom 1.5 tesla. Display matrix was 256x256. A Modulated Helmholtz type coil of 17 cm in diameter was developed in Kameda General Hospital in order to increase signal to noise ratio in the area of bilateral TMJs. The distance between two coils was 16-20 cm. The head was placed in supine position in the center of two surface coils. A Modulated Helmholtz type coil: 1. Modulated Helmholtz type coil was used as an emitter and a receiver. 2. Modulated Helmholtz type coil had a pair of 17 cm coils, which were movable according to head width of each patient. 3. MR imaging of bilateral TMJs was taken at once because of no necessity to reset a surfacecoil. 4. It was easy to set positioning of the head. (author).

  4. Immediate post-abortal insertion of intrauterine devices.

    Science.gov (United States)

    Grimes, D; Schulz, K; Stanwood, N

    2000-01-01

    topical hydrogel to a Spring Coil did not offer benefit. Overall, rates of perforation and pelvic inflammatory disease were low. Insertion of an IUD immediately after abortion is both safe and practical. This was true for both induced and reported "spontaneous" abortions, many of which may have been induced under clandestine circumstances. IUD expulsion rates were higher after second-trimester abortions than after earlier abortions, so delaying insertion may be advisable after later abortions. Although Copper 7 devices inserted unrelated to pregnancy may perform better than those inserted after abortion, many women who express interest in intrauterine contraception do not return for the scheduled insertion. These women may remain unprotected against unintended pregnancy. However, evidence is inadequate to compare the safety and efficacy of IUD insertion immediately after abortion vs. insertion some weeks later.

  5. The effect of MR surface coils on PET quantification in whole-body PET/MR: results from a pseudo-PET/MR phantom study.

    Science.gov (United States)

    Tellmann, L; Quick, H H; Bockisch, A; Herzog, H; Beyer, T

    2011-05-01

    The use of magnetic resonance (MR) radiofrequency (RF) surface coils is a prerequisite for high-quality positron emission tomography (PET)/MR imaging. In lack of in-gantry transmission (TX) sources, the exact position of the RF coils is unknown in PET/MR, and may, therefore, lead to false attenuation correction (AC) of the emission (EM) data. The authors assess lesion and background quantification in AC-PET by mimicking different PET/MR imaging situations using a whole-body (WB) PET-only tomograph. Phantom experiments were performed on a PET tomograph with 68 Ge-rod TX sources. First, a 15-cm plastic cylinder was filled uniformly with [18F]-FDG to simulate a head study. Second, a NEMA NU-2001 image quality phantom (35 x 25 x 25 cm3) was filled uniformly with [18F]-FDG to simulate torso imaging. The phantom contained six lesions (10-38 mm diameter, lesion-to-background ratio 6:1) centred around a 5 cm diameter lung insert. EM and TX measurements were acquired with and without MR head (cylinder) and surface (NU-2001 phantom) RF coils in place. The following imaging situations were mimicked in both head and torso phantom studies: (1) PET scan without MR coils in EM and TX for reference, (2) PET scan with coils in both EM and TX, and (3) PET scan with coils in EM but without coils in TX. Two more set-ups were performed for the torso phantom: (4) PET scan with coils in EM only and phantom shifted slightly compared to (3), and (5) PET scan with coils in EM and TX following local displacement of the surface coils. PET EM data (1)-(4) were corrected for attenuation and scatter using cold TX data. Imaging situations (1)-(3) were repeated with the cylinder phantom and head coil in a combined PET/MR prototype system employing template-based AC. Head phantom: In case the MR head coils were not accounted for during AC (3), central and peripheral background activity concentration was underestimated by 13%-19% when compared to the reference setup (1). The effects of MR coil

  6. A Steel Wire Stress Measuring Sensor Based on the Static Magnetization by Permanent Magnets

    Directory of Open Access Journals (Sweden)

    Dongge Deng

    2016-10-01

    Full Text Available A new stress measuring sensor is proposed to evaluate the axial stress in steel wires. Without using excitation and induction coils, the sensor mainly consists of a static magnetization unit made of permanent magnets and a magnetic field measurement unit containing Hall element arrays. Firstly, the principle is illustrated in detail. Under the excitation of the magnetization unit, a spatially varying magnetized region in the steel wire is utilized as the measurement region. Radial and axial magnetic flux densities at different lift-offs in this region are measured by the measurement unit to calculate the differential permeability curve and magnetization curve. Feature parameters extracted from the curves are used to evaluate the axial stress. Secondly, the special stress sensor for Φ5 and Φ7 steel wires is developed accordingly. At last, the performance of the sensor is tested experimentally. Experimental results show that the sensor can measure the magnetization curve accurately with the error in the range of ±6%. Furthermore, the obtained differential permeability at working points 1200 A/m and 10000 A/m change almost linearly with the stress in steel wires, the goodness of linear fits are all higher than 0.987. Thus, the proposed steel wire stress measuring sensor is feasible.

  7. Weyl fermions in cylindrical wires

    Science.gov (United States)

    Erementchouk, Mikhail; Mazumder, Pinaki

    2018-01-01

    The key feature of Weyl semimetals (WSMs) is the presence of topologically protected Dirac cones in a three-dimensional material. We consider the effect of restricting geometry on the spectrum of excitations in WSMs using as a model a cylindrical WSM wire. For the full manifold of hard boundary conditions, we derive the general form of the dispersion equation relating the energy of the excitations and their momentum along the wire. We show that only the special class of boundary conditions, corresponding to decoupled helicities or, equivalently, to pinned directions of the electron spin on the surface, support massless excitations. For a general boundary condition, these excitations acquire mass inversely proportional to the radius of the wire. This demonstrates that boundary phenomena may play a crucial role in formation of excitations in WSM based structures.

  8. A Quiet Gradient-Coil Set Employing Optimized, Force-Shielded, Distributed Coil Designs

    Science.gov (United States)

    Chapman, B. L. W.; Mansfield, P.

    1995-05-01

    A distributed coil design is described which employs active force shielding to reduce acoustic noise. Both axial and transverse gradients employ sets of distributed pairs of coplanar closed-are loops whose planes are normal to the static magnetic field direction. The resulting gradients are also partially magnetically screened. The design results in an axially compact coil set that provides linear gradients which extend over greater fractions of the enclosed volume than previous designs. The minimal gradient field interaction with the patient inherent in this force-shielded transverse-gradient coil design provides intrinsically safer Gx and Gy gradient fields.

  9. MR Performance Comparison of a PET/MR System Before and After SiPM-Based Time-of-Flight PET Detector Insertion

    Science.gov (United States)

    Khalighi, Mohammad Mehdi; Delso, Gaspar; Maramraju, Sri Harsha; Deller, Timothy W.; Levin, Craig S.; Glover, Gary H.

    2016-10-01

    A silicon photomultiplier (SiPM)-based time-of-flight capable PET detector has been integrated with a 70 cm wide-bore 3T MR scanner for simultaneous whole-body imaging (MR750w, GE Healthcare, Waukesha, WI). After insertion of the PET detector, the final PET/MR bore is 60 cm wide (SIGNA PET/MR, GE Healthcare, Waukesha, WI). The MR performance was compared before and after the PET ring insertion. B0 homogeneity, B1+ uniformity of the body coil along with peak B1+, coherent noise, and FBIRN (Function Biomedical Informatics Research Network) tests are used to compare the MR performance. It is shown that B0 homogeneity and coherent noise have not changed according to the system specifications. Peak B1+ is increased by 33% and B1+ inhomogeneity is increased by 4% after PET ring insertion due to a smaller diameter body coil design. The FBIRN test shows similar temporal stability before and after PET ring insertion. Due to a smaller body coil on the PET/MR system, the signal fluctuation to noise ratio (SFNR) and SNR for body receive coil, are improved by 40% and 160% for Echo Planar Imaging (EPI) and spiral sequences respectively. Comparison using RF- and gradient-intensive clinical sequences shows inserting the PET detectors into the wide-bore MRI has not compromised the MR image quality according to these tests.

  10. The Short Model Coil (SMC) dipole: an R&D program towards Nb3Sn accelerator magnets

    CERN Document Server

    Bajko, M; Canfer, S; Ellwood, G; Feuvrier, J; Guinchard, M; Karppinen, M; Kokkinos, C; Manil, P; Milanese, A; Oberli, L; Perez, J-C; Regis, F; de Rijk, G

    2011-01-01

    The Short Model Coil (SMC) assembly has been designed, as test bench for short racetrack coils wound with Nb3Sn cable. The mechanical structure comprises an iron yoke surrounded by a 20 mm thick aluminium alloy shell, and includes four loading pads that transmit the required pre-compression from the outer shell into the two coils. The outer shell is pre-tensioned with mechanical keys that are inserted with the help of pressurized bladders and two 30 mm diameter aluminium alloy rods provide the axial loading to the coil ends. The outer shell, the axial rods, and the coils are instrumented with strain gauges, which allow precise monitoring of the loading conditions during the assembly and at cryogenic temperature during the magnet test. Two SMC assemblies have been completed and cold tested in the frame of a European collaboration between CEA (FR), CERN and STFC (UK) and with the technical support from LBNL (US). This paper describes the main features of the SMC assembly, the experience from the dummy assemblie...

  11. The SMC (Short Model Coil) dipole: An R&D program for Nb3Sn accelerator magnets

    CERN Document Server

    Perez, J C; Bordini, B; Canfer, S; Ellwood, G; Feuvrier, J; Guinchard, M; Karppinen, M; Kokkinos, C; Manil, P; Milanese, A; Oberli, L; Regis, F; de Rijk, G

    2012-01-01

    The Short Model Coil (SMC) assembly has been designed, as test bench for short racetrack coils wound with Nb3Sn cable. The mechanical structure comprises an iron yoke surrounded by a 20 mm thick aluminium alloy shell, and includes four loading pads that transmit the required pre-compression from the outer shell into the two coils. The outer shell is pre-tensioned with mechanical keys that are inserted with the help of pressurized bladders and two 30 mm diameter aluminium alloy rods provide the axial loading to the coil ends. The outer shell, the axial rods, and the coils are instrumented with strain gauges, which allow precise monitoring of the loading conditions during the assembly and at cryogenic temperature during the magnet test. Two SMC assemblies have been completed and cold tested in the frame of a European collaboration between CEA (FR), CERN and STFC (UK) and with the technical support from LBNL (US). This paper describes the main features of the SMC assembly, the experience from the dummy assembli...

  12. Gene Insertion Patterns and Sites

    Science.gov (United States)

    Vain, Philippe; Thole, Vera

    During the past 25 years, the molecular analysis of transgene insertion patterns and sites in plants has greatly contributed to our understanding of the mechanisms underlying transgene integration, expression, and stability in the nuclear genome. Molecular characterization is also an essential step in the safety assessment of genetically modified crops. This chapter describes the standard experimental procedures used to analyze transgene insertion patterns and loci in cereals and grasses transformed using Agrobacterium tumefaciens or direct transfer of DNA. Methods and protocols enabling the determination of the number and configuration of transgenic loci via a combination of inheritance studies, polymerase chain reaction, and Southern analyses are presented. The complete characterization of transgenic inserts in plants is, however, a holistic process relying on a wide variety of experimental approaches. In this chapter, these additional approaches are not detailed but references to relevant bibliographic records are provided.

  13. Rogowski coils for studies of detonator initiation

    Science.gov (United States)

    Tasker, Douglas

    2017-06-01

    The Rogowski coil dates back to 1887 and it has commonly been employed to measure rapid changes of electrical currents without direct contact with the circuits, especially in high energy density applications. Recently, it has been used to measure currents in relatively low energy devices such as semiconductor circuits; here we report its utility in the analysis of detonator initiation. From an electrical perspective, the coil is essentially an air-cored transformer and measures the temporal rate of change of current dI/dt. Following a careful characterization of the circuit, an accurate measurement of this derivative is shown to provide a complete solution of the detonator circuit, including current, voltage, power and energy delivered to the detonator. The dependence of the electrical sensitivity, accuracy and bandwidth on coil design will be discussed and a new printed circuit design will be presented. Interesting features in the initiation of exploding bridgewire detonators have been observed with this coil and the results of various experiments will be discussed.

  14. Coil in bottom part of splitter magnet

    CERN Multimedia

    CERN PhotoLab

    1976-01-01

    Radiation-resistant coil being bedded into the bottom part of a splitter magnet. This very particular magnet split the beam into 3 branches, for 3 target stations in the West-Area. See Annual Report 1975, p.176, Figs.14 and 15.

  15. Stellarator Coil Design and Plasma Sensitivity

    Energy Technology Data Exchange (ETDEWEB)

    Long-Poe Ku and Allen H. Boozer

    2010-11-03

    The rich information contained in the plasma response to external magnetic perturbations can be used to help design stellarator coils more effectively. We demonstrate the feasibility by first devel- oping a simple, direct method to study perturbations in stellarators that do not break stellarator symmetry and periodicity. The method applies a small perturbation to the plasma boundary and evaluates the resulting perturbed free-boundary equilibrium to build up a sensitivity matrix for the important physics attributes of the underlying configuration. Using this sensitivity information, design methods for better stellarator coils are then developed. The procedure and a proof-of-principle application are given that (1) determine the spatial distributions of external normal magnetic field at the location of the unperturbed plasma boundary to which the plasma properties are most sen- sitive, (2) determine the distributions of external normal magnetic field that can be produced most efficiently by distant coils, (3) choose the ratios of the magnitudes of the the efficiently produced magnetic distributions so the sensitive plasma properties can be controlled. Using these methods, sets of modular coils are found for the National Compact Stellarator Experiment (NCSX) that are either smoother or can be located much farther from the plasma boundary than those of the present design.

  16. Modular Coils and Plasma Configurations for Quasi-axisymmetric Stellarators

    Energy Technology Data Exchange (ETDEWEB)

    L.P. Ku and A.H. Boozer

    2010-09-10

    Characteristics of modular coils for quasi-axisymmetric stellarators that are related to the plasma aspect ratio, number of field periods and rotational transform have been examined systematically. It is observed that, for a given plasma aspect ratio, the coil complexity tends to increase with the increased number of field periods. For a given number of field periods, the toroidal excursion of coil winding is reduced as the plasma aspect ratio is increased. It is also clear that the larger the coil-plasma separation is, the more complex the coils become. It is further demonstrated that it is possible to use other types of coils to complement modular coils to improve both the physics and the modular coil characteristics.

  17. Mechanical design of a high field common coil magnet

    CERN Document Server

    Caspi, S; Dietderich, D R; Gourlay, S A; Gupta, R; McInturff, A; Millos, G; Scanlan, R M

    1999-01-01

    A common coil design for high field 2-in-1 accelerator magnets has been previously presented as a "conductor-friendly" option for high field magnets applicable for a Very Large Hadron Collider. This paper presents the mechanical design for a 14 tesla 2-in-1 dipole based on the common coil design approach. The magnet will use a high current density Nb/sub 3/Sn conductor. The design addresses mechanical issues particular to the common coil geometry: horizontal support against coil edges, vertical preload on coil faces, end loading and support, and coil stresses and strains. The magnet is the second in a series of racetrack coil magnets that will provide experimental verification of the common coil design approach. (9 refs).

  18. Mechanical design of a high field common coil magnet

    Energy Technology Data Exchange (ETDEWEB)

    Caspi, S.; Chow, K.; Dietderich, D.; Gourlay, S.; Gupta, R.; McInturff, A.; Millos, G.; Scanlan, R.

    1999-03-18

    A common coil design for high field 2-in-1 accelerator magnets has been previously presented as a 'conductor-friendly' option for high field magnets applicable for a Very Large Hadron Collider. This paper presents the mechanical design for a 14 tesla 2-in-1 dipole based on the common coil design approach. The magnet will use a high current density Nb{sub 3}Sn conductor. The design addresses mechanical issues particular to the common coil geometry: horizontal support against coil edges, vertical preload on coil faces, end loading and support, and coil stresses and strains. The magnet is the second in a series of racetrack coil magnets that will provide experimental verification of the common coil design approach.

  19. Antiparallel coiled-coil–mediated dimerization of myosin X

    Science.gov (United States)

    Lu, Qing; Ye, Fei; Wei, Zhiyi; Wen, Zilong; Zhang, Mingjie

    2012-01-01

    Processive movements of unconventional myosins on actin filaments generally require motor dimerization. A commonly accepted myosin dimerization mechanism is via formation of a parallel coiled-coil dimer by a stretch of amino acid residues immediately carboxyl-terminal to the motor’s lever-arm domain. Here, we discover that the predicted coiled-coil region of myosin X forms a highly stable, antiparallel coiled-coil dimer (anti-CC). Disruption of the anti-CC either by single-point mutations or by replacement of the anti-CC with a parallel coiled coil with a similar length compromised the filopodial induction activity of myosin X. We further show that the anti-CC and the single α-helical domain of myosin X are connected by a semirigid helical linker. The anti-CC–mediated dimerization may enable myosin X to walk on both single and bundled actin filaments. PMID:23012428

  20. d-Cysteine Ligands Control Metal Geometries within De Novo Designed Three-Stranded Coiled Coils

    DEFF Research Database (Denmark)

    Ruckthong, Leela; Peacock, Anna F.A.; Pascoe, Cherilyn E.

    2017-01-01

    Although metal ion binding to naturally occurring l-amino acid proteins is well documented, understanding the impact of the opposite chirality (d-)amino acids on the structure and stereochemistry of metals is in its infancy. We examine the effect of a d-configuration cysteine within a designed l......-amino acid three-stranded coiled coil in order to enforce a precise coordination number on a metal center. The d chirality does not alter the native fold, but the side-chain re-orientation modifies the sterics of the metal binding pocket. l-Cys side chains within the coiled-coil structure have previously...... been shown to rotate substantially from their preferred positions in the apo structure to create a binding site for a tetra-coordinate metal ion. However, here we show by X-ray crystallography that d-Cys side chains are preorganized within a suitable geometry to bind such a ligand. This is confirmed...

  1. Design, Fabrication and Initial Testing of a Large Bore Single Aperture 1 m Long Superconducting Dipole Made with Phenolic Inserts

    CERN Document Server

    Boschmann, H; Kirby, G A; Lucas, J; Ostojic, R; Russenschuck, Stephan; Siemko, A; Vanenkov, I; Weterings, W

    1997-01-01

    In the framework of the LHC magnet development programme, a large bore single aperture 1-meter long superconducting dipole has been built in collaboration with HOLEC. The magnet features a single layer coil wound using the LHC main dipole outer layer cable, phenolic inserts, and a keyed two part structural iron yoke. This paper presents the magnetic and mechanical design and optimisation of the magnet. We describe the coil winding and curing, and present the construction and assembly procedures. Finally we report on the mechanical behaviour during assembly and cooling, and present the magnet training behaviour.

  2. Subchannel Analysis of Wire Wrapped SCWR Assembly

    National Research Council Canada - National Science Library

    Shan, Jianqiang; Wang, Henan; Liu, Wei; Song, Linxing; Chen, Xuanxiang; Jiang, Yang

    2014-01-01

    .... The HPLWR wire wrapped assembly was analyzed. The results show that: (1) the assembly with wire wrap can obtain a more uniform coolant temperature profile than the grid spaced assembly, which will result in a lower peak cladding temperature; (2...

  3. GBNV encoded movement protein (NSm) remodels ER network via C-terminal coiled coil domain

    Energy Technology Data Exchange (ETDEWEB)

    Singh, Pratibha; Savithri, H.S., E-mail: bchss@biochem.iisc.ernet.in

    2015-08-15

    Plant viruses exploit the host machinery for targeting the viral genome–movement protein complex to plasmodesmata (PD). The mechanism by which the non-structural protein m (NSm) of Groundnut bud necrosis virus (GBNV) is targeted to PD was investigated using Agrobacterium mediated transient expression of NSm and its fusion proteins in Nicotiana benthamiana. GFP:NSm formed punctuate structures that colocalized with mCherry:plasmodesmata localized protein 1a (PDLP 1a) confirming that GBNV NSm localizes to PD. Unlike in other movement proteins, the C-terminal coiled coil domain of GBNV NSm was shown to be involved in the localization of NSm to PD, as deletion of this domain resulted in the cytoplasmic localization of NSm. Treatment with Brefeldin A demonstrated the role of ER in targeting GFP NSm to PD. Furthermore, mCherry:NSm co-localized with ER–GFP (endoplasmic reticulum targeting peptide (HDEL peptide fused with GFP). Co-expression of NSm with ER–GFP showed that the ER-network was transformed into vesicles indicating that NSm interacts with ER and remodels it. Mutations in the conserved hydrophobic region of NSm (residues 130–138) did not abolish the formation of vesicles. Additionally, the conserved prolines at positions 140 and 142 were found to be essential for targeting the vesicles to the cell membrane. Further, systematic deletion of amino acid residues from N- and C-terminus demonstrated that N-terminal 203 amino acids are dispensable for the vesicle formation. On the other hand, the C-terminal coiled coil domain when expressed alone could also form vesicles. These results suggest that GBNV NSm remodels the ER network by forming vesicles via its interaction through the C-terminal coiled coil domain. Interestingly, NSm interacts with NP in vitro and coexpression of these two proteins in planta resulted in the relocalization of NP to PD and this relocalization was abolished when the N-terminal unfolded region of NSm was deleted. Thus, the NSm

  4. A REVIEW ON HEAT TRANSFER THROUGH HELICAL COIL HEAT EXCHANGERS

    OpenAIRE

    Surendra Vishvakarma*, Sanjay Kumbhare, K. K. Thakur

    2016-01-01

    This study presents a brief review of heat transfer through helical coil heat exchangers. Helical coils of circular cross section have been used in wide variety of applications due to simplicity in manufacturing. Enhancement in heat transfer due to helical coils has been reported by many researchers. While the heat transfer characteristics of double pipe helical heat exchangers are available in the literature, there exists no published experimental or theoretical analysis of a helically coile...

  5. Compressing DNA sequence databases with coil

    Directory of Open Access Journals (Sweden)

    Hendy Michael D

    2008-05-01

    Full Text Available Abstract Background Publicly available DNA sequence databases such as GenBank are large, and are growing at an exponential rate. The sheer volume of data being dealt with presents serious storage and data communications problems. Currently, sequence data is usually kept in large "flat files," which are then compressed using standard Lempel-Ziv (gzip compression – an approach which rarely achieves good compression ratios. While much research has been done on compressing individual DNA sequences, surprisingly little has focused on the compression of entire databases of such sequences. In this study we introduce the sequence database compression software coil. Results We have designed and implemented a portable software package, coil, for compressing and decompressing DNA sequence databases based on the idea of edit-tree coding. coil is geared towards achieving high compression ratios at the expense of execution time and memory usage during compression – the compression time represents a "one-off investment" whose cost is quickly amortised if the resulting compressed file is transmitted many times. Decompression requires little memory and is extremely fast. We demonstrate a 5% improvement in compression ratio over state-of-the-art general-purpose compression tools for a large GenBank database file containing Expressed Sequence Tag (EST data. Finally, coil can efficiently encode incremental additions to a sequence database. Conclusion coil presents a compelling alternative to conventional compression of flat files for the storage and distribution of DNA sequence databases having a narrow distribution of sequence lengths, such as EST data. Increasing compression levels for databases having a wide distribution of sequence lengths is a direction for future work.

  6. Plasmodium vivax antigen discovery based on alpha-helical coiled coil protein motif.

    Directory of Open Access Journals (Sweden)

    Nora Céspedes

    Full Text Available Protein α-helical coiled coil structures that elicit antibody responses, which block critical functions of medically important microorganisms, represent a means for vaccine development. By using bioinformatics algorithms, a total of 50 antigens with α-helical coiled coil motifs orthologous to Plasmodium falciparum were identified in the P. vivax genome. The peptides identified in silico were chemically synthesized; circular dichroism studies indicated partial or high α-helical content. Antigenicity was evaluated using human sera samples from malaria-endemic areas of Colombia and Papua New Guinea. Eight of these fragments were selected and used to assess immunogenicity in BALB/c mice. ELISA assays indicated strong reactivity of serum samples from individuals residing in malaria-endemic regions and sera of immunized mice, with the α-helical coiled coil structures. In addition, ex vivo production of IFN-γ by murine mononuclear cells confirmed the immunogenicity of these structures and the presence of T-cell epitopes in the peptide sequences. Moreover, sera of mice immunized with four of the eight antigens recognized native proteins on blood-stage P. vivax parasites, and antigenic cross-reactivity with three of the peptides was observed when reacted with both the P. falciparum orthologous fragments and whole parasites. Results here point to the α-helical coiled coil peptides as possible P. vivax malaria vaccine candidates as were observed for P. falciparum. Fragments selected here warrant further study in humans and non-human primate models to assess their protective efficacy as single components or assembled as hybrid linear epitopes.

  7. Application of Coiled Coil Peptides in Liposomal Anticancer Drug Delivery Using a Zebrafish Xenograft Model.

    Science.gov (United States)

    Yang, Jian; Shimada, Yasuhito; Olsthoorn, René C L; Snaar-Jagalska, B Ewa; Spaink, Herman P; Kros, Alexander

    2016-08-23

    The complementary coiled coil forming peptides E4 [(EIAALEK)4] and K4 [(KIAALKE)4] are known to trigger liposomal membrane fusion when tethered to lipid vesicles in the form of lipopeptides. In this study, we examined whether these coiled coil forming peptides can be used for drug delivery applications. First, we prepared E4 peptide modified liposomes containing the far-red fluorescent dye TO-PRO-3 iodide (E4-Lipo-TP3) and confirmed that E4-liposomes could deliver TP3 into HeLa cells expressing K4 peptide on the membrane (HeLa-K) under cell culture conditions in a selective manner. Next, we prepared doxorubicin-containing E4-liposomes (E4-Lipo-DOX) and confirmed that E4-liposomes could also deliver DOX into HeLa-K cells. Moreover, E4-Lipo-DOX showed enhanced cytotoxicity toward HeLa-K cells compared to free doxorubicin. To prove the suitability of E4/K4 coiled coil formation for in vivo drug delivery, we injected E4-Lipo-TP3 or E4-Lipo-DOX into zebrafish xenografts of HeLa-K. As a result, E4-liposomes delivered TP3 to the implanted HeLa-K cells, and E4-Lipo-DOX could suppress cancer proliferation in the xenograft when compared to nontargeted conditions (i.e., zebrafish xenograft with free DOX injection). These data demonstrate that coiled coil formation enables drug selectivity and efficacy in vivo. It is envisaged that these findings are a step forward toward biorthogonal targeting systems as a tool for clinical drug delivery.

  8. CCBuilder 2.0: Powerful and accessible coiled-coil modeling.

    Science.gov (United States)

    Wood, Christopher W; Woolfson, Derek N

    2018-01-01

    The increased availability of user-friendly and accessible computational tools for biomolecular modeling would expand the reach and application of biomolecular engineering and design. For protein modeling, one key challenge is to reduce the complexities of 3D protein folds to sets of parametric equations that nonetheless capture the salient features of these structures accurately. At present, this is possible for a subset of proteins, namely, repeat proteins. The α-helical coiled coil provides one such example, which represents ≈ 3-5% of all known protein-encoding regions of DNA. Coiled coils are bundles of α helices that can be described by a small set of structural parameters. Here we describe how this parametric description can be implemented in an easy-to-use web application, called CCBuilder 2.0, for modeling and optimizing both α-helical coiled coils and polyproline-based collagen triple helices. This has many applications from providing models to aid molecular replacement for X-ray crystallography, in silico model building and engineering of natural and designed protein assemblies, and through to the creation of completely de novo "dark matter" protein structures. CCBuilder 2.0 is available as a web-based application, the code for which is open-source and can be downloaded freely. http://coiledcoils.chm.bris.ac.uk/ccbuilder2. We have created CCBuilder 2.0, an easy to use web-based application that can model structures for a whole class of proteins, the α-helical coiled coil, which is estimated to account for 3-5% of all proteins in nature. CCBuilder 2.0 will be of use to a large number of protein scientists engaged in fundamental studies, such as protein structure determination, through to more-applied research including designing and engineering novel proteins that have potential applications in biotechnology. © 2017 The Authors Protein Science published by Wiley Periodicals, Inc. on behalf of The Protein Society.

  9. Coiled-coil forming peptides for the induction of silver nanoparticles

    Energy Technology Data Exchange (ETDEWEB)

    Božič Abram, Sabina [Department of Synthetic Biology and Immunology, National Institute of Chemistry, Hajdrihova 19, 1000 Ljubljana (Slovenia); Graduate School of Biomedicine, University of Ljubljana, Ljubljana 1000 (Slovenia); Aupič, Jana [Department of Synthetic Biology and Immunology, National Institute of Chemistry, Hajdrihova 19, 1000 Ljubljana (Slovenia); Doctoral Programme in Chemical Sciences, Faculty of Chemistry and Chemical Technology, University of Ljubljana, Ljubljana 1000 (Slovenia); Dražić, Goran [Laboratory for Materials Chemistry, National Institute of Chemistry, Hajdrihova 19, 1000 Ljubljana (Slovenia); Gradišar, Helena [Department of Synthetic Biology and Immunology, National Institute of Chemistry, Hajdrihova 19, 1000 Ljubljana (Slovenia); EN-FIST, Centre of Excellence, Trg Osvobodilne fronte 13, Ljubljana 1000 (Slovenia); Jerala, Roman, E-mail: roman.jerala@ki.si [Department of Synthetic Biology and Immunology, National Institute of Chemistry, Hajdrihova 19, 1000 Ljubljana (Slovenia); EN-FIST, Centre of Excellence, Trg Osvobodilne fronte 13, Ljubljana 1000 (Slovenia)

    2016-04-08

    Biopolymers with defined sequence patterns offer an attractive alternative for the formation of silver nanoparticle (AgNP). A set of coiled-coil dimer forming peptides was tested for their AgNP formation ability. Seventeen of those peptides mediated the formation of AgNPs in aqueous solution at neutral pH, while the formation of a coiled-coil dimer inhibited the nanoparticle generation. A QSAR regression model on the relationship between sequence and function suggests that in this peptide type the patterns KXQQ and KXEE are favorable, whereas Ala residues appear to have an inhibitory effect. UV–VIS spectra of the obtained nanoparticles gave a peak at around 420 nm, typical for AgNPs in the size range around 40 nm, which was confirmed by dynamic light scattering and transmission electron microscopy. Peptide-induced AgNPs exhibited good antibacterial activity, even after a 15 min contact time, while they had low toxicity to human cells at the same concentrations. These results show that our designed peptides generate AgNPs with antibacterial activity at mild conditions and might be used for antibacterial coatings. - Highlights: • 17 of the 30 tested coiled-coil forming peptides induce AgNP formation. • Coiled-coil dimer formation suppresses AgNP generation of individual peptides. • Size of the peptide-induced silver nanoparticles is around 40 nm. • QSAR analysis points to the importance of KXQQ and KXEE motifs for AgNP generation. • Peptide-induced silver nanoparticles exhibit antibacterial activity.

  10. Transparency in nanophotonic quantum wires

    Energy Technology Data Exchange (ETDEWEB)

    Singh, Mahi R [Department of Physics and Astronomy, University of Western Ontario, London N6A 3K7 (Canada)

    2009-03-28

    We have studied the quantum optics of a photonic quantum nanowire doped with an ensemble of three-level nanoparticles. The wire is made from two photonic crystals A and B. Crystal A is embedded within crystal B and acts as a photonic nanowire. It is considered that the conduction band of crystal A lies below that of crystal B. As a result, photons are confined in crystal A and are reflected from crystal B. The bound states of the confined photons are calculated using the transfer matrix method. It is found that the number of bound states in the wire depends on the size of the wire and the energy difference between the conduction band extrema of crystals A and B. The absorption coefficient of the system has also been calculated using the Schroedinger equation method. It is considered that the nanoparticles interact with the photonic bound states. Numerical simulations show that when one of the resonance energies lies near the bound state, the system becomes transparent. However, when the resonance energy lies away from the bound state the crystal reverts to an absorbing state. Similarly, when the radius of the dielectric spheres is changed the location of the transparency peak is shifted. This means that the present system can be switched between two states by changing the size of the wire and the transition energy. These findings can be used to make new types of optical devices.

  11. Signal shapes in a TPC wire chamber

    Science.gov (United States)

    Rossegger, S.; Riegler, W.

    2010-11-01

    We study signal shapes in Multi Wire Proportional Chambers (MWPCs) and the influence of the electron distribution around the wire on the ion tail characteristics. Simulations of the ion tail for two different geometries, different voltages and therefore gas gains were performed. These simulations are compared to measurements carried out with the ALICE TPC wire chambers for a Ne/CO 2/N 2 gas mixture, which allows to extract the avalanche spread around the anode wires of the MWPC.

  12. Towards Unconventional Applications of Wire Bonding

    OpenAIRE

    Schröder, Stephan

    2018-01-01

    This thesis presents novel heterogeneous integration approaches of wire materials to fabricated and package MEMS devices by exploring unconventional applications of wire bonding technology. Wire bonding, traditionally endemic in the realm of device packaging to establish electrical die-to-package interconnections, is an attractive back-end technology, offering promising features, such as high throughput, flexibility and placement accuracy. Exploiting the advantages of state-of-the-art wire bo...

  13. Novel Wiring Technologies for Aerospace Applications

    Science.gov (United States)

    Gibson, Tracy L.; Parrish, Lewis M.

    2014-01-01

    Because wire failure in aerospace vehicles could be catastrophic, smart wiring capabilities have been critical for NASA. Through the years, researchers at Kennedy Space Center (KSC) have developed technologies, expertise, and research facilities to meet this need. In addition to aerospace applications, NASA has applied its knowledge of smart wiring, including self-healing materials, to serve the aviation industry. This webinar will discuss the development efforts of several wiring technologies at KSC and provide insight into both current and future research objectives.

  14. Electron transport in stretched monoatomic gold wires.

    Science.gov (United States)

    Grigoriev, A; Skorodumova, N V; Simak, S I; Wendin, G; Johansson, B; Ahuja, R

    2006-12-08

    The conductance of monoatomic gold wires containing 3-7 gold atoms has been obtained from ab initio calculations. The transmission is found to vary significantly depending on the wire stretching and the number of incorporated atoms. Such oscillations are determined by the electronic structure of the one-dimensional (1D) part of the wire between the contacts. Our results indicate that the conductivity of 1D wires can be suppressed without breaking the contact.

  15. Transport of one SC coil through the village of Meyrin

    CERN Multimedia

    1956-01-01

    The energizing coils of the Synchro-cyclotron magnet were manufactured in Belgium before travelling to Basel in Switzerland by boat and continuing by road to Geneva. The first coil reached Geneva in December 1955, with the second following in early 1956. The coils were stored in a hangar at the Geneva airport before they were brought to CERN in May 1956.

  16. The Roach muscle bundle and umbilical cord coiling

    NARCIS (Netherlands)

    de Laat, Monique W. M.; Nikkels, Peter G. J.; Franx, Arie; Visser, Gerard H. A.

    2007-01-01

    To determine if presence of the Roach muscle, a small muscle bundle lying just beside the umbilical artery, contributes to umbilical cord coiling. 251 umbilical cords were examined. The umbilical coiling index (UCI) was calculated as the number of coils divided by the cord length in cm. Cords were

  17. The umbilical coiling index, a review of the literature

    NARCIS (Netherlands)

    de Laat, Monique W. M.; Franx, Arie; van Alderen, Elise D.; Nikkels, Peter G. J.; Visser, Gerard H. A.

    2005-01-01

    Our aim was to review the literature on umbilical cord coiling. Relevant articles in English published between 1966 and 2003 were retrieved by a Medline search and cross-referencing. The normal umbilical cord coiling index (UCI) is 0.17 (+/- 0.009) spirals completed per cm. Abnormal cord coiling,

  18. Radiofrequency coils for magnetic resonance applications: theory, design, and evaluation.

    Science.gov (United States)

    Giovannetti, Giulio; Hartwig, Valentina; Positano, Vincenzo; Vanello, Nicola

    2014-01-01

    Magnetic resonance imaging and magnetic resonance spectroscopy are noninvasive diagnostic techniques based on the phenomenon of nuclear magnetic resonance. Radiofrequency coils are key components in both the transmission and receiving phases of magnetic resonance systems. Transmitter coils have to produce a highly homogeneous alternating field in a wide field of view, whereas receiver coils have to maximize signal detection while minimizing noise. Development of modern magnetic resonance coils often is based on numerical methods for simulating and predicting coil performance. Numerical methods allows the behavior of the coil in the presence of realistic loads to be simulated and the coil's efficiency at high magnetic fields to be investigated. After being built, coils have to be characterized in the laboratory to optimize their setting and performance by extracting several quality indices. Successively, coils performance has to be evaluated in a scanner using standardized image quality parameters with phantom and human experiments. This article reviews the principles of radiofrequency coils, coil performance parameters, and their estimation methods using simulations, workbench, and magnetic resonance experiments. Finally, an overview of future developments in radiofrequency coils technology is included.

  19. Historical review: another 50th anniversary--new periodicities in coiled coils.

    Science.gov (United States)

    Gruber, Markus; Lupas, Andrei N

    2003-12-01

    In 1953, Francis Crick and Linus Pauling both proposed models of supercoiled alpha helices ('coiled coils') for the structure of keratin. These were the first attempts at modelling the tertiary structure of a protein. Crick emphasized the packing mode of the side-chains ('knobs-into-holes'), which required a periodicity of seven residues over two helical turns (7/2) and a supercoil in the opposite sense of the constituent helices. By contrast, Pauling envisaged a broader set of periodicities (4/1, 7/2, 18/5, 15/4, 11/3) and supercoils of both senses. Crick's model became canonical and the 'heptad repeat' essentially synonymous with coiled coils, but 50 years later new crystal structures and protein sequences show that the less common periodicities envisaged by Pauling also occur in coiled coils, adding a variant packing mode ('knobs-to-knobs') to the standard model. Pauling's laboratory notebooks suggest that he searched unsuccessfully for this packing mode in 1953.

  20. Coiled-Coil Proteins Facilitated the Functional Expansion of the Centrosome

    Science.gov (United States)

    Kuhn, Michael; Hyman, Anthony A.; Beyer, Andreas

    2014-01-01

    Repurposing existing proteins for new cellular functions is recognized as a main mechanism of evolutionary innovation, but its role in organelle evolution is unclear. Here, we explore the mechanisms that led to the evolution of the centrosome, an ancestral eukaryotic organelle that expanded its functional repertoire through the course of evolution. We developed a refined sequence alignment technique that is more sensitive to coiled coil proteins, which are abundant in the centrosome. For proteins with high coiled-coil content, our algorithm identified 17% more reciprocal best hits than BLAST. Analyzing 108 eukaryotic genomes, we traced the evolutionary history of centrosome proteins. In order to assess how these proteins formed the centrosome and adopted new functions, we computationally emulated evolution by iteratively removing the most recently evolved proteins from the centrosomal protein interaction network. Coiled-coil proteins that first appeared in the animal–fungi ancestor act as scaffolds and recruit ancestral eukaryotic proteins such as kinases and phosphatases to the centrosome. This process created a signaling hub that is crucial for multicellular development. Our results demonstrate how ancient proteins can be co-opted to different cellular localizations, thereby becoming involved in novel functions. PMID:24901223

  1. Detection of a buried wire with two resistively loaded wire antennas

    NARCIS (Netherlands)

    Vossen, S.H.J.A.; Tijhuis, A.G.; Lepelaars, E.S.A.M.; Zwamborn, A.P.M.

    2002-01-01

    The use of two identical straight thin-wire antennas for the detection of a buried wire is analyzed with the aid of numerical calculations. The buried wire is located below an interface between two homogeneous half-spaces. The detection setup, which is formed by a transmitting and a receiving wire,

  2. Home and School Technology: Wired versus Wireless.

    Science.gov (United States)

    Van Horn, Royal

    2001-01-01

    Presents results of informal research on smart homes and appliances, structured home wiring, whole-house audio/video distribution, hybrid cable, and wireless networks. Computer network wiring is tricky to install unless all-in-one jacketed cable is used. Wireless phones help installers avoid pre-wiring problems in homes and schools. (MLH)

  3. Electrochemistry of surface wired cytochrome c and ...

    Indian Academy of Sciences (India)

    Pyrazine unit in the mixed self-assembly promotes the electron transfer in the redox reaction of surface wired Cyt-c. Cyt-c wired on the mixed self-assembly has been used for the amperometric sensing of superoxide. The enzymatically generated superoxide has been successfully detected using the Cyt-c wired electrode.

  4. 49 CFR 393.28 - Wiring systems.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 5 2010-10-01 2010-10-01 false Wiring systems. 393.28 Section 393.28 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL MOTOR CARRIER SAFETY... NECESSARY FOR SAFE OPERATION Lamps, Reflective Devices, and Electrical Wiring § 393.28 Wiring systems...

  5. Customised 2G HTS wire for applications

    Science.gov (United States)

    Samoilenkov, S.; Molodyk, A.; Lee, S.; Petrykin, V.; Kalitka, V.; Martynova, I.; Makarevich, A.; Markelov, A.; Moyzykh, M.; Blednov, A.

    2016-02-01

    Reproducibility of superconducting properties and suitability for specific applications by means of customised finish are two important attributes required from commercial 2G HTS wire. This paper reviews the consistent performance of SuperOx production 2G HTS wire and describes two novel customisation options: surround polyimide varnish insulation and composite bulk materials assembled with 2G HTS wires soldered together.

  6. The influence of wire localisation for non-palpable breast lesions on visualisation of the sentinel node

    Energy Technology Data Exchange (ETDEWEB)

    Jansen, J.E.; Bekker, J.; Verberne, G.H.M. [Meander Medical Center, Department of Surgery, Amersfoort (Netherlands); Haas, M.J. de; Weel, F.A. van der; Quekel, L.G.B.A. [Meander Medical Center, Department of Nuclear Medicine and Radiology, Amersfoort (Netherlands); Budel, L.M. [Meander Medical Center, Department of Pathology, Amersfoort (Netherlands); Klerk, J.M.H. de [Meander Medical Center, Department of Nuclear Medicine and Radiology, Amersfoort (Netherlands); University Medical Center Utrecht, Department of Nuclear Medicine, Utrecht (Netherlands)

    2006-11-15

    In our clinic, patients with occult breast lesions are treated with a sentinel node biopsy combined with wire-guided tumour excision. The aim of this retrospective study was to determine the influence of the sequence of wire localisation and sentinel node procedure on visualisation of the sentinel node. A total of 136 patients had a wire-guided tumour excision combined with a sentinel node procedure. Sixty-six patients had guide wire localisation prior to the sentinel node procedure. Seventy patients had sentinel node visualisation before insertion of the guide wire. The sentinel node was visualised in 41 (62%) of the patients who first underwent guide wire localisation. In the group of patients who underwent visualisation of the sentinel node before placement of the guide wire, the sentinel node was visualised in 62 (89%). This is a significant difference in visualisation (p<0.001). This study shows that guide wire localisation prior to the sentinel node procedure negatively influences visualisation of the sentinel node. (orig.)

  7. Concepts for stereoselective acrylate insertion

    KAUST Repository

    Neuwald, Boris

    2013-01-23

    Various phosphinesulfonato ligands and the corresponding palladium complexes [{((PaO)PdMeCl)-μ-M}n] ([{( X1-Cl)-μ-M}n], (PaO) = κ2- P,O-Ar2PC6H4SO2O) with symmetric (Ar = 2-MeOC6H4, 2-CF3C6H4, 2,6-(MeO)2C6H3, 2,6-(iPrO)2C 6H3, 2-(2′,6′-(MeO)2C 6H3)C6H4) and asymmetric substituted phosphorus atoms (Ar1 = 2,6-(MeO)2C6H 3, Ar2 = 2′-(2,6-(MeO)2C 6H3)C6H4; Ar1 = 2,6-(MeO)2C6H3, Ar2 = 2-cHexOC 6H4) were synthesized. Analyses of molecular motions and dynamics by variable temperature NMR studies and line shape analysis were performed for the free ligands and the complexes. The highest barriers of ΔGa = 44-64 kJ/mol were assigned to an aryl rotation process, and the flexibility of the ligand framework was found to be a key obstacle to a more effective stereocontrol. An increase of steric bulk at the aryl substituents raises the motional barriers but diminishes insertion rates and regioselectivity. The stereoselectivity of the first and the second methyl acrylate (MA) insertion into the Pd-Me bond of in situ generated complexes X1 was investigated by NMR and DFT methods. The substitution pattern of the ligand clearly affects the first MA insertion, resulting in a stereoselectivity of up to 6:1 for complexes with an asymmetric substituted phosphorus. In the consecutive insertion, the stereoselectivity is diminished in all cases. DFT analysis of the corresponding insertion transition states revealed that a selectivity for the first insertion with asymmetric (P aO) complexes is diminished in the consecutive insertions due to uncooperatively working enantiomorphic and chain end stereocontrol. From these observations, further concepts are developed. © 2012 American Chemical Society.

  8. Regulation of c-Fes Tyrosine Kinase and Biological Activities by N-Terminal Coiled-Coil Oligomerization Domains

    Science.gov (United States)

    Cheng, Haiyun; Rogers, Jim A.; Dunham, Nancy A.; Smithgall, Thomas E.

    1999-01-01

    The cytoplasmic protein-tyrosine kinase Fes has been implicated in cytokine signal transduction, hematopoiesis, and embryonic development. Previous work from our laboratory has shown that active Fes exists as a large oligomeric complex in vitro. However, when Fes is expressed in mammalian cells, its kinase activity is tightly repressed. The Fes unique N-terminal sequence has two regions with strong homology to coiled-coil-forming domains often found in oligomeric proteins. Here we show that disruption or deletion of the first coiled-coil domain upregulates Fes tyrosine kinase and transforming activities in Rat-2 fibroblasts and enhances Fes differentiation-inducing activity in myeloid leukemia cells. Conversely, expression of a Fes truncation mutant consisting only of the unique N-terminal domain interfered with Rat-2 fibroblast transformation by an activated Fes mutant, suggesting that oligomerization is essential for Fes activation in vivo. Coexpression with the Fes N-terminal region did not affect the transforming activity of v-Src in Rat-2 cells, arguing against a nonspecific suppressive effect. Taken together, these findings suggest a model in which Fes activation may involve coiled-coil-mediated interconversion of monomeric and oligomeric forms of the kinase. Mutation of the first coiled-coil domain may activate Fes by disturbing intramolecular coiled-coil interaction, allowing for oligomerization via the second coiled-coil domain. Deletion of the second coiled-coil domain blocks fibroblast transformation by an activated form of c-Fes, consistent with this model. These results provide the first evidence for regulation of a nonreceptor protein-tyrosine kinase by coiled-coil domains. PMID:10567558

  9. Mechanical evaluation of hip cement spacer reinforcement with stainless steel Kirschner wires, titanium and carbon rods, and stainless steel mesh.

    Science.gov (United States)

    Kaku, Nobuhiro; Tabata, Tomonori; Tsumura, Hiroshi

    2015-04-01

    In two-stage treatments for infections after total hip arthroplasty, antibiotic-loaded cement spacers help treat the infection by antibiotic elution and prevent contraction. However, such spacers are weak and may fracture while awaiting replacement, impairing functionality. We evaluated whether a Kirschner wire (K-wire) mounted into the spacer reinforced its strength along with the effects of the reinforcing material, position, and intensity. Spacers without reinforcing materials constituted the control group. As reinforcing materials, stainless steel K-wires (diameters 3 and 6 mm), titanium alloy and carbon fibers (diameter 3.175 mm), and stainless steel meshes (inner and outer diameters, 6 and 9 mm, respectively) were inserted into the spacer mold before filling with cement. The spacers complied with ISO 7206-4; a compressive load was applied using a testing machine with a velocity of 25.4 mm/min, and the maximum load was recorded. We used 1-3 K-wires positioned on the medial side, lateral side, neck only, and stem only and tested 3 specimens for each condition. The control group withstood the highest load. Stainless steel was the strongest material; 3-mm K-wires in the neck and lateral side withstood a higher load. The computed tomography (CT) imaging revealed a cavity between the K-wires and cement. When K-wires were inserted along the whole length, despite cement fractures, continuity was maintained because of the reinforcing materials. It is difficult to improve the reinforcing strength of spacers using K-wires; however, K-wires prevented dislocation of cement spacer fragments, which can help prevent contraction and facilitate spacer removal during replacement.

  10. Radio frequency coil technology for small-animal MRI.

    Science.gov (United States)

    Doty, F David; Entzminger, George; Kulkarni, Jatin; Pamarthy, Kranti; Staab, John P

    2007-05-01

    A review of the theory, technology, and use of radio frequency (RF) coils for small-animal MRI is presented. It includes a brief overview of MR signal-to-noise (S/N) analysis and discussions of the various coils commonly used in small-animal MR: surface coils, linear volume coils, birdcages, and their derivatives. The scope is limited to mid-range coils, i.e. coils where the product (fd) of the frequency f and the coil diameter d is in the range 2-30 MHz-m. Common applications include mouse brain and body coils from 125 to 750 MHz, rat body coils up to 500 MHz, and small surface coils at all fields. In this regime, all the sources of loss (coil, capacitor, sample, shield, and transmission lines) are important. All such losses may be accurately captured in some modern full-wave 3D electromagnetics software, and new simulation results are presented for a selection of surface coils using Microwave Studio 2006 by Computer Simulation Technology, showing the dramatic importance of the "lift-off effect". Standard linear circuit simulators have been shown to be useful in optimization of complex coil tuning and matching circuits. There appears to be considerable potential for trading S/N for speed using phased arrays, especially for a larger field of view. Circuit simulators are shown to be useful for optimal mismatching of ultra-low-noise preamps based on the enhancement-mode pseudomorphic high-electron-mobility transistor for optimal coil decoupling in phased arrays. Cryogenically cooled RF coils are shown to offer considerable opportunity for future gains in S/N in smaller samples.

  11. Computational study for the effects of coil configuration on blood flow characteristics in coil-embolized cerebral aneurysm.

    Science.gov (United States)

    Otani, Tomohiro; Ii, Satoshi; Shigematsu, Tomoyoshi; Fujinaka, Toshiyuki; Hirata, Masayuki; Ozaki, Tomohiko; Wada, Shigeo

    2017-05-01

    Coil embolization of cerebral aneurysms with inhomogeneous coil distribution leads to an incomplete occlusion of the aneurysm. However, the effects of this factor on the blood flow characteristics are still not fully understood. This study investigates the effects of coil configuration on the blood flow characteristics in a coil-embolized aneurysm using computational fluid dynamics (CFD) simulation. The blood flow analysis in the aneurysm with coil embolization was performed using a coil deployment (CD) model, in which the coil configuration was constructed using a physics-based simulation of the CD. In the CFD results, total flow momentum and kinetic energy in the aneurysm gradually decayed with increasing coil packing density (PD), regardless of the coil configuration attributed to deployment conditions. However, the total shear rate in the aneurysm was relatively high and the strength of the local shear flow varied based on the differences in coil configuration, even at adequate PDs used in clinical practice (20-25 %). Because the sufficient shear rate reduction is a well-known factor in the blood clot formation occluding the aneurysm inside, the present study gives useful insight into the effects of coil configuration on the treatment efficiency of coil embolization.

  12. Fluoroscopic insertion of post-pyloric feeding tubes: success rates and complications

    Energy Technology Data Exchange (ETDEWEB)

    Thurley, P.D.; Hopper, M.A. [Department of Clinical Radiology, Nottingham University Hospitals NHS Trust, Nottingham (United Kingdom); Jobling, J.C. [Department of Clinical Radiology, Nottingham University Hospitals NHS Trust, Nottingham (United Kingdom)], E-mail: craig.jobling@nuh.nhs.uk; Teahon, K. [Department of Clinical Radiology, Nottingham University Hospitals NHS Trust, Nottingham (United Kingdom)

    2008-05-15

    Aim: To examine the success and complication rates of radiological placement of post-pyloric feeding tubes, including those inserted with the assistance of a guide-wire. Materials and Methods: Two hundred referrals (156 patients), between the dates of 5 April 2002 and 10 September 2004, were identified retrospectively from computerized records. Subsequently, the radiology reports and patients' notes were reviewed to evaluate the indications for post-pyloric feeding, success of placement, use of a guide-wire, and any complications. Results: A post-pyloric tube was placed in the distal duodenum/jejunum in 183 (91.5%) patients and in the proximal duodenum or distal stomach in six (3%). A tube could not be inserted in 11 (5.5%) patients, and 51 (25.5%) of the insertions required the use of a guide-wire. Immediate complications were recorded in seven patients (3.5%): vomiting (n = 5); hypotension and apnoea requiring naloxone (n = 1) and hypoxia requiring endotracheal intubation (n = 1). Conclusion: Radiological placement of post-pyloric feeding tubes has a success rate comparable with endoscopically placed tubes, and it rarely involves significant technique-related complications.

  13. SSC (Superconducting Super Collider) dipole coil production tooling

    Energy Technology Data Exchange (ETDEWEB)

    Carson, J.A.; Barczak, E.J.; Bossert, R.C.; Brandt, J.S.; Smith, G.A.

    1989-03-01

    Superconducting Super Collider dipole coils must be produced to high precision to ensure uniform prestress and even conductor distribution within the collared coil assembly. Tooling is being prepared at Fermilab for the production of high precision 1M and 16.6M SSC dipole coils suitable for mass production. The design and construction methods builds on the Tevatron tooling and production experience. Details of the design and construction methods and measured coil uniformity of 1M coils will be presented. 4 refs., 10 figs.

  14. Umbilical Cord Coiling and Zygosity: Is there a Link?

    Science.gov (United States)

    Coetzee, André Joannou; Castro, Eumenia; Peres, Luiz Cesar

    2015-01-01

    The aim of this study was to analyze abnormalities of umbilical coiling index (UCI) in twin gestation to test whether the coiling is genetically influenced by zygosity. Data retrieved comprised gestational age (GA), chorionicity, fetal gender, and UCI. The mean UCI of hypercoiled cords in monochorionic placentas was 0.55 coils/cm and 0.49 coils/cm in dichorionic placentas with discordant fetal gender (P = 0.2629). In conclusion, no significant statistical difference between UCI in monochorionic and dichorionic twin placentas with discordant fetal gender was identified, suggesting that zygosity does not play a role in umbilical coiling induction.

  15. Construction of the ATLAS B0 model coil

    CERN Document Server

    Daël, A; Alessandria, F; Berriaud, C; Berthier, R; Broggi, F; Mayri, C; Pabot, Y; Rey, J M; Reytier, M; Rossi, L; Sorbi, M; Van Hille, H; Volpini, G; Sun, Z

    2001-01-01

    The B0 coil is a technological model for the ATLAS Barrel Toroid coils. The major concepts and the construction procedures are the same as those specified for the BT coils. So the manufacturing feasibility has been extensively proved and the technological developments have been carried out for the industrial production of the conductor, the welding technique of the coil casing, the prestress of the coil with bladders, the cold to warm supports, the construction and assembly of the cryostat. The paper illustrates all these phases. (4 refs).

  16. Cochlear Dummy Electrodes for Insertion Training and Research Purposes: Fabrication, Mechanical Characterization, and Experimental Validation

    Directory of Open Access Journals (Sweden)

    Jan-Philipp Kobler

    2015-01-01

    Full Text Available To develop skills sufficient for hearing preservation cochlear implant surgery, surgeons need to perform several electrode insertion trials in ex vivo temporal bones, thereby consuming relatively expensive electrode carriers. The objectives of this study were to evaluate the insertion characteristics of cochlear electrodes in a plastic scala tympani model and to fabricate radio opaque polymer filament dummy electrodes of equivalent mechanical properties. In addition, this study should aid the design and development of new cochlear electrodes. Automated insertion force measurement is a new technique to reproducibly analyze and evaluate the insertion dynamics and mechanical characteristics of an electrode. Mechanical properties of MED-EL’s FLEX28, FLEX24, and FLEX20 electrodes were assessed with the help of an automated insertion tool. Statistical analysis of the overall mechanical behavior of the electrodes and factors influencing the insertion force are discussed. Radio opaque dummy electrodes of comparable characteristics were fabricated based on insertion force measurements. The platinum-iridium wires were replaced by polymer filament to provide sufficient stiffness to the electrodes and to eradicate the metallic artifacts in X-ray and computed tomography (CT images. These low-cost dummy electrodes are cheap alternatives for surgical training and for in vitro, ex vivo, and in vivo research purposes.

  17. Emittance growth due to Tevatron flying wires

    Energy Technology Data Exchange (ETDEWEB)

    Syphers, M; Eddy, Nathan

    2004-06-01

    During Tevatron injection, Flying Wires have been used to measure the transverse beam size after each transfer from the Main Injector in order to deduce the transverse emittances of the proton and antiproton beams. This amounts to 36 + 9 = 45 flies of each of 3 wire systems, with an individual wire passing through each beam bunch twice during a single ''fly''. below they estimate the emittance growth induced by the interaction of the wires with the particles during these measurements. Changes of emittance from Flying Wire measurements conducted during three recent stores are compared with the estimations.

  18. Simultaneous PET/MR imaging with a radio frequency-penetrable PET insert.

    Science.gov (United States)

    Grant, Alexander M; Lee, Brian J; Chang, Chen-Ming; Levin, Craig S

    2017-01-01

    A brain sized radio frequency (RF)-penetrable PET insert has been designed for simultaneous operation with MRI systems. This system takes advantage of electro-optical coupling and battery power to electrically float the PET insert relative to the MRI ground, permitting RF signals to be transmitted through small gaps between the modules that form the PET ring. This design facilitates the use of the built-in body coil for RF transmission and thus could be inserted into any existing MR site wishing to achieve simultaneous PET/MR imaging. The PET detectors employ nonmagnetic silicon photomultipliers in conjunction with a compressed sensing signal multiplexing scheme, and optical fibers to transmit analog PET detector signals out of the MRI room for decoding, processing, and image reconstruction. The PET insert was first constructed and tested in a laboratory benchtop setting, where tomographic images of a custom resolution phantom were successfully acquired. The PET insert was then placed within a 3T body MRI system, and tomographic resolution/contrast phantom images were acquired both with only the B0 field present, and under continuous pulsing from different MR imaging sequences. The resulting PET images have comparable contrast-to-noise ratios (CNR) under all MR pulsing conditions: The maximum percent CNR relative difference for each rod type among all four PET images acquired in the MRI system has a mean of 14.0 ± 7.7%. MR images were successfully acquired through the RF-penetrable PET shielding using only the built-in MR body coil, suggesting that simultaneous imaging is possible without significant mutual interference. These results show promise for this technology as an alternative to costly integrated PET/MR scanners; a PET insert that is compatible with any existing clinical MRI system could greatly increase the availability, accessibility, and dissemination of PET/MR. © 2016 American Association of Physicists in Medicine.

  19. Separation and preconcentration by flow injection coupled to tungsten coil electrothermal atomic absorption spectrometry

    Science.gov (United States)

    Silva, Márcia M.; Krug, Francisco J.; Oliveira, Pedro V.; Nóbrega, Joaquim A.; Reis, Boaventura F.; Penteado, Daniel A. G.

    1996-12-01

    A flow injection system coupled to a tungsten coil electrothermal atomizer has been developed for on-line separation and preconcentration, using lead as a model element. The system utilizes three-way solenoid valves for sampling, buffering, washing and reconditioning solution management, and the resin column is inserted in the tip of the autosampler arm of a Varian GTA-96. The solenoid valves and tungsten coil power supply were controlled by a computer program written in Visual Basic, interfaced with the built-in Varian software. The system performance was tested by loading the resin column with the sample flowing at 3 ml min -1 for 60 s. Elution was performed automatically by sampling 20 μl of the eluent from a sample cup of the autosampler, and this aliquot was delivered into a 150 W tungsten coil. With Chelex-100 resin, the separation of concomitants was tested with lead in the presence of as much as 1000 mg l -1 of Ca, Mg, Na or K. The model system presented an enrichment factor of 64 at a sampling rate of 30 samples per hour.

  20. Wedge and spring assembly for securing coils in electromagnets and dynamoelectric machines

    Science.gov (United States)

    Lindner, M.; Cottingham, J.G.

    1996-03-12

    A wedge and spring assembly for use in electromagnets or dynamoelectric machines is disclosed having a housing with an axis therethrough and a plurality of coils supported on salient poles that extend radially inward from the housing toward the housing axis to define a plurality of interpole spaces. The wedge and spring assembly includes a nonmagnetic retainer spring and a nonmagnetic wedge. The retainer spring is formed to fit into one of the interpole spaces, and has juxtaposed ends defining between them a slit extending in a direction generally parallel to the housing axis. The wedge for insertion into the slit provides an outwardly directed force on respective portions of the juxtaposed ends to expand the slit so that respective portions of the retainer spring engage areas of the coils adjacent thereto, thereby resiliently holding the coils against their respective salient poles. The retainer spring is generally triangular shaped to fit within the interpole space, and the wedge is generally T-shaped. 6 figs.

  1. Deep brain transcranial magnetic stimulation using variable "Halo coil" system

    Science.gov (United States)

    Meng, Y.; Hadimani, R. L.; Crowther, L. J.; Xu, Z.; Qu, J.; Jiles, D. C.

    2015-05-01

    Transcranial Magnetic Stimulation has the potential to treat various neurological disorders non-invasively and safely. The "Halo coil" configuration can stimulate deeper regions of the brain with lower surface to deep-brain field ratio compared to other coil configurations. The existing "Halo coil" configuration is fixed and is limited in varying the site of stimulation in the brain. We have developed a new system based on the current "Halo coil" design along with a graphical user interface system that enables the larger coil to rotate along the transverse plane. The new system can also enable vertical movement of larger coil. Thus, this adjustable "Halo coil" configuration can stimulate different regions of the brain by adjusting the position and orientation of the larger coil on the head. We have calculated magnetic and electric fields inside a MRI-derived heterogeneous head model for various positions and orientations of the coil. We have also investigated the mechanical and thermal stability of the adjustable "Halo coil" configuration for various positions and orientations of the coil to ensure safe operation of the system.

  2. Guide Wire Induced Cardiac Tamponade: The Soft J Tip Is Not So Benign

    Directory of Open Access Journals (Sweden)

    Sankalp Dwivedi

    2016-01-01

    Full Text Available Central venous catheter (CVC insertion rarely causes cardiac tamponade due to perforation. Although it is a rare complication, it can be lethal if not identified early. We report a case of cardiac tamponade caused by internal jugular (IJ central venous catheter (CVC insertion using a soft J-tipped guide wire which is considered safe and rarely implicated with cardiac tamponade. A bedside transthoracic echocardiogram (TTE revealed a pericardial effusion with tamponade. An emergent bedside pericardiocentesis was done revealing bloody fluid and resulted in clinical stabilization.

  3. On the magnetic and magnetoelastic uniformity measurements on magnetostrictive ribbons and wires

    Energy Technology Data Exchange (ETDEWEB)

    Petridis, C. [Laboratory of Physical Metallurgy, National Technical University of Athens, Zografou Campus, Athens 15780 (Greece); Ktena, A. [Technological Education Institute of Chalkis, Euboea 34400 (Greece); Bolshakova, I. [Magnetic Sensor Laboratory, LPNU, 12 Bandera Str., Lviv 79013 (Ukraine); Hristoforou, E. [Laboratory of Physical Metallurgy, National Technical University of Athens, Zografou Campus, Athens 15780 (Greece)]. E-mail: eh@metal.ntua.gr

    2007-09-15

    In this paper, results on magnetic and magnetoelastic uniformity measurements concerning magnetostrictive ribbons are presented. Measurements are based on the magnetostrictive delay line (MDL) technique, which is used for the determination of B(H) and {lambda}(H) loops of long magnetostrictive ribbons, wires and rods of uniform rectangular cross section. The principle of operation for the B(H) and {lambda}(H) loop determination is based on the biasing field effect at the receiving and excitation coil of the MDL, respectively. The automated device used allowed the in situ parametric control of field, frequency, temperature and mechanical stress. The magnetic and magnetoelastic softening of amorphous Fe-Si-B ribbons, after stress-current annealing, is illustrated. This technique may be used for the non-destructive quality control of magnetostrictive ribbons and wires, used as sensing cores.

  4. Coil irrigation in sugar cane (Saccharum officinarum

    Directory of Open Access Journals (Sweden)

    Jesús Sánchez Gutiérrez

    2016-01-01

    Full Text Available This study was made at the Basic Seed Bank of the Local Sugar Cane Research Station for the Mideastern Cuba, based in Camaguey, on brown carbonate soil, between 2013 and 12014. Coil irrigation was applied to meet the water requirements for the crop, according to the edafoclimatic conditions and the different phenological phases it has. The Savo method was used to determine useful rain water. Adjustment and complementation of the irrigation program was based on indicators that characterize the exploitation scheme. The machine´s working parameters were determined to meet the water needs, and increase crop´s overall yields. The evaluations and results achieved have contributed to new proposals for management and operation of coil irrigation, and they are important to increase its efficiency.

  5. Toroidal high temperature superconducting coils for ISTTOK

    Energy Technology Data Exchange (ETDEWEB)

    Fernandes, H., E-mail: hf@ipfn.ist.utl.pt [Associacao Euratom/IST, Instituto de Plasmas e Fusao Nuclear, Laboratorio Associado, Instituto Superior Tecnico, 1049-001 Lisboa (Portugal); Goemoery, F. [Institute of Electrical Engineering, Slovak Academy of Sciences, Dubravska cesta 9, 84104 Bratislava (Slovakia); Corte, A. della; Celentano, G. [ENEA C.R. Frascati, Via E. Fermi 45, 00044 Frascati (Italy); Souc, J. [Institute of Electrical Engineering, Slovak Academy of Sciences, Dubravska cesta 9, 84104 Bratislava (Slovakia); Silva, C.; Carvalho, I.; Gomes, R. [Associacao Euratom/IST, Instituto de Plasmas e Fusao Nuclear, Laboratorio Associado, Instituto Superior Tecnico, 1049-001 Lisboa (Portugal); Di Zenobio, A.; Messina, G. [ENEA C.R. Frascati, Via E. Fermi 45, 00044 Frascati (Italy)

    2011-10-15

    High temperature superconductors (HTS) are very attractive to be used in fusion devices mainly due to lower operations costs. The HTS technology has reached a point where the construction of toroidal field coils for a tokamak is possible. The feasibility of a tokamak operating with HTS is extremely relevant and ISTTOK is the ideal candidate for a meaningful test due to its small size (and consequently lower cost) and the possibility to operate in a steady-state inductive regime. In this paper, a conceptual study of the ISTTOK upgrade to a superconducting device is presented, along with the relevant boundary conditions to achieve a permanent toroidal field with HTS. It is shown that the actual state of the art in HTS allows the design of a toroidal field coil capable of generating the appropriate field on plasma axis while respecting the structural specification of the machine.

  6. In situ calibration of rotating sensor coils for magnet testing.

    Science.gov (United States)

    Arpaia, P; Buzio, M; Golluccio, G; Walckiers, L

    2012-01-01

    An in situ procedure for calibrating equivalent magnetic area and rotation radius of rotating coils is proposed for testing accelerator magnets shorter than the measuring coil. The procedure exploits measurements of magnetic field and mechanical displacement inside a reference quadrupole magnet. In a quadrupole field, an offset between the magnet and coil rotation axes gives rise to a dipole component in the field series expansion. The measurements of the focusing strength, the displacement, and the resulting dipole term allow the equivalent area and radius of the coil to be determined analytically. The procedure improves the accuracy of coils with large geometrical irregularities in the winding. This is essential for short magnets where the coil dimensions constrain the measurement accuracy. Experimental results on different coils measuring small-aperture permanent magnets are shown.

  7. Plasma formation in metallic wire Z pinches

    Science.gov (United States)

    Chittenden; Lebedev; Ruiz-Camacho; Beg; Bland; Jennings; Bell; Haines; Pikuz; Shelkovenko; Hammer

    2000-04-01

    Plasma formation in metallic wire Z pinches is modeled using a two-dimensional resistive magnetohydrodynamics code. Modified Thomas-Fermi equations of state and dense plasma transport coefficients allow the phase transitions from solid to plasma to be approximated. Results indicate the persistence of a two-component structure with a cold, dense core embedded within a much hotter, low density, m=0 unstable corona. Extensive benchmark testing against data from a number of single-wire experiments is presented. Artificial laser schlieren and x-ray back-lighting images generated from the code data are compared directly to experimental results. The results were found to be insensitive to inaccuracies in the equations of state and transport coefficients. Simulations of individual wires in a wire array show different behavior to that observed experimentally due to the absence of three-dimensional effects. Simulations with similar conditions to wires in an array show a general trend in the plasma structure at start of implosion from discrete wires with large m=0 perturbation amplitudes to partially merged wires with smaller perturbation amplitudes as the number of wires is increased. Results for a wire number scan with aluminum wire arrays on the SATURN generator suggest that the observed sharp transition to high x-ray power at around 40 wires corresponds to a sharp decrease in m=0 perturbation amplitude and hence a sharp decrease in the seed perturbation for the Rayleigh-Taylor instability.

  8. Voice coil based scanning probe microscopy

    Czech Academy of Sciences Publication Activity Database

    Klapetek, P.; Valtr, M.; Duchoň, V.; Sobota, Jaroslav

    2012-01-01

    Roč. 7, č. 6 (2012), 332:1-7 ISSN 1931-7573 R&D Projects: GA MPO FR-TI1/241; GA AV ČR KAN311610701; GA MŠk ED0017/01/01 Institutional support: RVO:68081731 Keywords : SPM * Voice coil * Interferometry Subject RIV: BM - Solid Matter Physics ; Magnetism Impact factor: 2.524, year: 2012

  9. Micro Chemical Oxygen-Iodine Laser (COIL)

    Science.gov (United States)

    2007-10-01

    until it reached its set point at around -5’C. Once the set points of pressure and temperature had been reached, the chlorine, flowing concurrently ...literature. Future work includes testing multiple pSOGs in tandem at their optimal operating conditions and using arrays of ptSOGs to drive a MEMS COIL...yields of 78%, comparing well with reactor model predictions. Topical Heading: 5. Reactors, Kinetics, and Catalysis ii INTRODUCTION Microchemical systems

  10. Coil irrigation in sugar cane (Saccharum officinarum)

    OpenAIRE

    Jesús Sánchez Gutiérrez; Yoslén Fernández Gálvez; Mayra Martínez Pírez; Camilo Bonet Pérez; Manuel A Hernández Victoria; Arlandy Noy Perera

    2016-01-01

    This study was made at the Basic Seed Bank of the Local Sugar Cane Research Station for the Mideastern Cuba, based in Camaguey, on brown carbonate soil, between 2013 and 12014. Coil irrigation was applied to meet the water requirements for the crop, according to the edafoclimatic conditions and the different phenological phases it has. The Savo method was used to determine useful rain water. Adjustment and complementation of the irrigation program was based on indicators that characterize the...

  11. Choice of coils for a fusion reactor

    Science.gov (United States)

    Alexander, Romeo; Garabedian, Paul R.

    2007-01-01

    In a fusion reactor a hot plasma of deuterium and tritium is confined by a strong magnetic field to produce helium ions and release energetic neutrons. The 3D geometry of a stellarator provides configurations for such a device that reduce net toroidal current that might lead to disruptions. We construct smooth coils generating an external magnetic field designed to prevent the plasma from deteriorating. PMID:17640879

  12. Numerical dosimetry of transcranial magnetic stimulation coils

    Science.gov (United States)

    Crowther, Lawrence; Hadimani, Ravi; Jiles, David

    2014-03-01

    Transcranial magnetic stimulation (TMS) is a non-invasive neuromodulation technique capable of stimulating neurons by means of electromagnetic induction. TMS can be used to map brain function and shows promise for the diagnosis and treatment of neurological and psychiatric disorders. Calculation of fields induced in the brain are necessary to accurately identify stimulated neural tissue during TMS. This allows the development of novel TMS coil designs capable of stimulating deeper brain regions and increasing the localization of stimulation that can be achieved. We have performed numerical calculations of magnetic and electric field with high-resolution anatomically realistic human head models to find these stimulated brain regions for a variety of proposed TMS coil designs. The realistic head models contain heterogeneous tissue structures and electrical conductivities, yielding superior results to those obtained from the simplified homogeneous head models that are commonly employed. The attenuation of electric field as a function of depth in the brain and the localization of stimulating field have been methodically investigated. In addition to providing a quantitative comparison of different TMS coil designs the variation of induced field between subjects has been investigated. We also show the differences in induced fields between adult, adolescent and child head models to preemptively identify potential safety issues in the application of pediatric TMS.

  13. Coiling and Folding of Viscoelastic Jets

    Science.gov (United States)

    Majmudar, Trushant; Varagnat, Matthieu; McKinley, Gareth

    2007-11-01

    The study of fluid jets impacting on a flat surface has industrial applications in many areas, including processing of foods and consumer goods, bottle filling, and polymer melt processing. Previous studies have focused primarily on purely viscous, Newtonian fluids, which exhibit a number of different dynamical regimes including dripping, steady jetting, folding, and steady coiling. Here we add another dimension to the problem by focusing on mobile (low viscosity) viscoelastic fluids, with the study of two wormlike-micellar fluids, a cetylpyridinum-salicylic acid salt (CPyCl/NaSal) solution, and an industrially relevant shampoo base. We investigate the effects of viscosity and elasticity on the dynamics of axi-symmetric jets. The viscoelasticity of the fluids is systematically controlled by varying the concentration of salt counterions. Experimental methods include shear and extensional rheology measurements to characterize the fluids, and high-speed digital video imaging. In addition to the regimes observed in purely viscous systems, we also find a novel regime in which the elastic jet buckles and folds on itself, and alternates between coiling and folding behavior. We suggest phase diagrams and scaling laws for the coiling and folding frequencies through a systematic exploration of the experimental parameter space (height of fall, imposed flow rate, elasticity of the solution).

  14. Sintered wire cesium dispenser photocathode

    Science.gov (United States)

    Montgomery, Eric J; Ives, R. Lawrence; Falce, Louis R

    2014-03-04

    A photoelectric cathode has a work function lowering material such as cesium placed into an enclosure which couples a thermal energy from a heater to the work function lowering material. The enclosure directs the work function lowering material in vapor form through a low diffusion layer, through a free space layer, and through a uniform porosity layer, one side of which also forms a photoelectric cathode surface. The low diffusion layer may be formed from sintered powdered metal, such as tungsten, and the uniform porosity layer may be formed from wires which are sintered together to form pores between the wires which are continuous from the a back surface to a front surface which is also the photoelectric surface.

  15. The first LHC insertion quadrupole

    CERN Multimedia

    2004-01-01

    An important milestone was reached in December 2003 at the CERN Magnet Assembly Facility. The team from the Accelerator Technology - Magnet and Electrical Systems group, AT-MEL, completed the first special superconducting quadrupole for the LHC insertions which house the experiments and major collider systems. The magnet is 8 metres long and contains two matching quadrupole magnets and an orbit corrector, a dipole magnet, used to correct errors in quadrupole alignment. All were tested in liquid helium and reached the ultimate performance criteria required for the LHC. After insertion in the cryostat, the superconducting magnet will be installed as the Q9 quadrupole in sector 7-8, the first sector of the LHC to be put in place in 2004. Members of the quadrupole team, from the AT-MEL group, gathered around the Q9 quadrupole at its inauguration on 12 December 2003 in building 181.

  16. Genetic Optimization of Wire Antennas

    Directory of Open Access Journals (Sweden)

    Z. Raida

    1998-09-01

    Full Text Available The presented submission describes how genetic algorithms can be applied to the optimization and design of wire antennas. The proposed optimization method is easily programmable and well understandable on one hand, but relatively slowly converging and depending on the parameters of the genetic algorithms on the other hand. The disadvantages of the method are deeply discussed and their elimination is discussed in the paper.

  17. Evidence of α-helical coiled coils and β-sheets in hornet silk.

    Science.gov (United States)

    Kameda, Tsunenori; Nemoto, Takashi; Ogawa, Tetsuya; Tosaka, Masatoshi; Kurata, Hiroki; Schaper, Andreas K

    2014-03-01

    α-Helical coiled coil and β-sheet complexes are essential structural building elements of silk proteins produced by different species of the Hymenoptera. Beside X-ray scattering at wide and small angles we applied cryo-electron diffraction and microscopy to demonstrate the presence and the details of such structures in silk of the giant hornet Vespa mandarinia japonica. Our studies on the assembly of the fibrous silk proteins and their internal organization in relation to the primary chain structure suggest a 172 Å pitch supercoil consisting of four intertwined alanine-rich α-helical strands. The axial periodicity may adopt even multiples of the pitch value. Coiled coil motifs form the largest portion of the hornet silk structure and are aligned nearly parallel to the cocoon fiber axis in the same way as the membrane-like parts of the cocoon are molecularly orientated in the spinning direction. Supercoils were found to be associated with β-crystals, predominantly localized in the l-serine-rich chain sequences terminating each of the four predominant silk proteins. Such β-sheet blocks are considered resulting from transformation of random coil molecular sequences due to the action of elongational forces during the spinning process. Copyright © 2013 Elsevier Inc. All rights reserved.

  18. Design and testing of a coil-unit barrel for helical coil electromagnetic launcher

    Science.gov (United States)

    Yang, Dong; Liu, Zhenxiang; Shu, Ting; Yang, Lijia; Ouyang, Jianming

    2018-01-01

    A coil-unit barrel for a helical coil electromagnetic launcher is described. It provides better features of high structural strength and flexible adjustability. It is convenient to replace the damaged coil units and easy to adjust the number of turns in the stator coils due to the modular design. In our experiments, the highest velocity measured for a 4.5-kg projectile is 47.3 m/s and the mechanical reinforcement of the launcher could bear 35 kA peak current. The relationship between the energy conversion efficiency and the inductance gradient of the launcher is also studied. In the region of low inductance gradient, the efficiency is positively correlated with the inductance gradient. However, in the region of high inductance gradient, the inter-turn arc erosion becomes a major problem of limiting the efficiency and velocity of the launcher. This modular barrel allows further studies in the inter-turn arc and the variable inductance gradient helical coil launcher.

  19. Hydrophilic polymer-coated microcatheter-guide wire system for superselective angiographic procedures

    Energy Technology Data Exchange (ETDEWEB)

    Kobayashi, Hisashi; Hiraki, Yoshiyuki; Nishimoto, Hidetou; Miyazono, Nobuaki; Satake, Mitsuo; Shinohara, Shinji

    1988-06-01

    A hydrophilic polymer-coated microcatheter-guide wire device has been newly developed for superselective angiography and interventional procedures. The injection rate of this microcatheter was estimated at 2.0 ml/sec. on the maximum pressure of 300 psi when used a non-ionic low osmolar contrast medium, Iopamidol 300. In two of three cases this catheter could make easy insertion into the peripheral branches of the right hepatic artery which were approximately 1 mm in vascular diameter.

  20. LHC Luminosity Upgrade Protecting Insertion Region Magnets from Collision Debris

    CERN Document Server

    Wildner, E; Ferrari, A; Mauri, M; Mereghetti, A

    2008-01-01

    The Large Hadron Collider built at CERN now enters a starting-up phase where the present design luminosity up to 1034 cm-2 s-1 will be reached after the running in phase. A possible upgrading of the machine to luminosity up to 10^35 cm^-2 s^-1 requires a new insertion region design, and will be implemented in essentially two phases. The energy from collision debris is deposited in the insertion regions and in particular in the superconducting magnet coils with a possible risk of quench. We describe here how to protect the interaction region magnets against this irradiation to keep the energy deposition below critical values estimated for safe operation. The constraint is to keep the absorber size as small as possible to leave most of the magnet aperture available for the beam. This can be done by choosing a suitable material and design minimizing the load on the cryogenic system. Here we will describe design proposals for the phase I upgrade lay-out, i.e. luminosity up to 2.5 10^34 cm^-2 s^-1.

  1. The Use of Solitaire AB Stents in Coil Embolization of Wide-Necked Cerebral Aneurysms.

    Directory of Open Access Journals (Sweden)

    Teng-Fei Li

    Full Text Available The Solitaire AB stent is one of many assistant stents used for treating wide-necked cerebral aneurysm, and has been used since 2003. However, large sample studies on its safety and effectiveness are lacking. The objective of this study was to evaluate the effectiveness and safety of the Solitaire AB stent in the coil embolization of wide-necked cerebral aneurysms.Retrospective review of the clinical and image data of 116 patients with wide-necked cerebral aneurysms who had been enrolled at six interventional neuroradiology centers from February 2010 to February 2014 and had been treated by coil embolization; in total, 120 Solitaire AB stents were used. The degree of aneurysm occlusion was examined using digital subtraction angiography (DSA immediately after the procedure and during follow-up, and was graded using the modified Raymond classification. We also observed complications to evaluate the safety and effectiveness of this therapy.The 120 Solitaire AB stents (4 mm × 15 mm, four stents; 4 mm × 20 mm, 16 stents; 6 mm × 20 mm, 36 stents; 6 mm × 30 mm, 64 stents were inserted to treat 120 wide-necked cerebral aneurysms. All stents were inserted successfully. DSA immediately post-surgery revealed 55 cases of complete occlusion, 59 cases of neck remnant, and six cases of aneurysm remnant. Perioperatively, there were four cases of hemorrhage and four cases of stent thrombosis. The follow-up spanned 3-37 months; of 92 patients examined by DSA at the 6-month follow up, 12 had disease recurrence.The Solitaire AB stent is effective with a good technical success rate and short-term effect for assisting coil embolization of wide-necked cerebral aneurysms.

  2. Synthesis and functionalization of coiled carbon filaments

    Science.gov (United States)

    Hikita, Muneaki

    Coiled carbon filaments have one of the most attractive three-dimensional forms in carbon materials due to their helical morphologies. Because of their shape and carbon structure, they exhibit excellent mechanical and electrical properties such as superelasticity, low Young's modulus, relatively high electrical conductivity, and good electromagnetic (EM) wave absorption. Therefore, they are good candidates as fillers in composite materials for tactile sensor and electromagnetic interference shielding. In medical areas of interests, coiled carbon filaments can be used as micro and nano heaters or trigger for thermotherapy and biosensors using EM wave exposure because absorbed EM waves by coiled carbon filaments are converted into heat. Although various shapes of coiled carbon filaments have been discovered, optimum synthesis conditions and growth mechanisms of coiled carbon filaments are poorly understood. The study of growth kinetics is significant not only to analyze catalyst activity but also to establish the growth mechanisms of coiled carbon filaments. The establishment of growth mechanisms would be useful for determining optimum synthesis conditions and maximizing the quantity of carbon filaments synthesized for a given application. In the first study, tip grown single helical carbon filaments or carbon nanocoils (CNCs) were synthesized by a chemical vapor deposition method using tin-iron-oxide (Sn-Fe-O) xerogel film catalyst. The Sn-Fe-O catalyst was prepared by a low-cost sol-gel method using stannous acetate and ferric acetate as precursors. The growth kinetics of CNCs were monitored by a thermogravimetric analyzer, and the experimental result was correlated using a one-dimensional kinetic model, corresponding to one-dimensional tip growth. In the second study, bidirectionally grown double helical filaments or carbon microcoils (CMCs) were synthesized using a chemical vapor deposition method. CMCs obtained at two reaction temperatures were compared. CMCs

  3. Procedure-related haemorrhage in embolisation of intracranial aneurysms with Guglielmi detachable coils

    Energy Technology Data Exchange (ETDEWEB)

    Kwon, B.J.; Kim, K.H. [Department of Radiology, Seoul National University College of Medicine, 28 Yongon-Dong, Chongno-Ku, 110-744, Seoul (Korea); Han, M.H.; Chang, K.H. [Department of Radiology, Seoul National University College of Medicine, 28 Yongon-Dong, Chongno-Ku, 110-744, Seoul (Korea); Clinical Research Institute, Seoul National University Hospital, 28 Yongon-Dong, Chongno-Ku, 110-744, Seoul (Korea); Institute of Radiation Medicine, Seoul National University Medical Research Centre, 28 Yongon-Dong, Chongno-Ku, 110-744, Seoul (Korea); Seoul National University College of Medicine (Korea); Oh, C.W. [Department of Neurosurgery, Seoul National University College of Medicine, 28 Yongon-Dong, Chongno-Ku, 110-744, Seoul (Korea)

    2003-08-01

    We reviewed the haemorrhagic complications of the endovascular treatment of intracranial aneurysms, in terms of frequency, pre-embolisation clinical status, clinical and radiological manifestations, management and prognosis. In 275 patients treated for 303 aneurysms over 7 years we had seven (one man and six women - 2.3%) with haemorrhage during or immediately after endovascular treatment. All procedures were performed with a standardised protocol of heparinisation and anaesthesia. Four had ruptured aneurysms, two at the tip of the basilar artery, and one ach on the internal carotid and posterior cerebral artery, treated after 12, 5, 14, and 2 days, respectively, three were in Hunt and Hess grade 2 and one in grade 1. Bleeding occurred during coiling in three, after placement of at least four coils, and during manipulation of the guidewire to enter the aneurysm in the fourth. Haemorrhage was manifest as extravasation of contrast medium, with a sudden rise in systolic blood pressure in three patients. The other three patients had unruptured aneurysms; they had stable blood pressure and angiographic findings during the procedure, but one, under sedation, had seizures immediately after insertion of four coils, and the other two had seizures, headache and vomiting on the day following the procedure. Heparin reversal with protamine sulphate was started promptly started when bleeding was detected in four patients, and the embolisation was completed with additional coils in three. Emergency ventricular drainage was performed in the two patients with ruptured aneurysm and one with an unruptured aneurysm who had abnormal neurological responses or hydrocephalus. The bleeding caused a third nerve palsy in one patient, which might have been due to ischaemia and progressively improved. (orig.)

  4. Current diffusion and normal zone propagation inside the aluminum stabilized superconductor of ATLAS model coil

    CERN Document Server

    Boxman, E W; Pellegatta, M; ten Kate, H H J

    2003-01-01

    The normal zone propagation inside the B/sub O/ model coil of the ATLAS Toroidal magnet has been measured over a large range of applied currents. Typical values for the longitudinal propagation vary from 0.3 to 15 m/s at 8 and 24 kA, respectively. A new analytical expression for the longitudinal quench propagation inside superconducting cables is presented. It describes the propagation inside superconducting wires as well as the propagation inside large stabilized superconductors. It is found that in the limit case of high currents, the stabilizer functions only as a heat-sink. The model is compared to experimental data and a good correlation is found. (10 refs).

  5. Influence of mechanical unloading on histological changes of the patellar tendon insertion in rabbits.

    Science.gov (United States)

    Mutsuzaki, Hirotaka; Nakajima, Hiromi; Wadano, Yasuyoshi; Takahashi, Hikaru; Sakane, Masataka

    2015-12-01

    The purpose of this study was to clarify the influence of mechanical unloading on histological changes of the patellar tendon (PT) insertion in rabbits. The PT was completely released from stress by drawing the patella toward the tibial tubercle with a stainless steel wire installed between the patella and tibial tubercle (mechanical unloading group, n=28). The animals of the sham group underwent the same surgical procedure; however, the wire was not tightened (n=28). The average thickness of the Safranin O-stained glycosaminoglycan (GAG) area, chondrocyte apoptosis rate and chondrocyte proliferation rate of the cartilage layer at the insertion were measured at one, two, four, and six weeks. The chondrocyte apoptosis rate in the mechanical unloading group was significantly higher than that in the sham group at one and four weeks (pmechanical unloading group was significantly lower than that in the sham group at four and six weeks (pmechanical unloading group was significantly lower than that in the sham group at six weeks (pMechanical unloading significantly affected the increase in the chondrocyte apoptosis rate, decrease in the chondrocyte proliferation rate, and decrease in the GAG layer thickness at the PT insertion for up to six weeks in rabbits. We suggest that more than 6 weeks of mechanical unloading should be avoided to prevent degeneration at the PT insertion. Copyright © 2015 Elsevier B.V. All rights reserved.

  6. Retrieval of prolapsed coils during endovascular treatment of cerebral aneurysms

    Energy Technology Data Exchange (ETDEWEB)

    Dinc, Hasan [Karadeniz Technical University, Department of Radiology, Faculty of Medicine, Trabzon (Turkey); KTU Farabi Hospital, Department of Radiology, Trabzon (Turkey); Kuzeyli, Kayhan [Karadeniz Technical University, Department of Neurosurgery, Faculty of Medicine, Trabzon (Turkey); Kosucu, Polat; Sari, Ahmet [Karadeniz Technical University, Department of Radiology, Faculty of Medicine, Trabzon (Turkey); Cekirge, Saruhan [Hacettepe University, Department of Radiology, Faculty of Medicine, Ankara (Turkey)

    2006-04-15

    One of the feared complications during detachable coil embolization of cerebral aneurysms is herniation of a coil loop into the parent artery. Although coil protrusion of one or two loops into the parent vessel may not cause adverse events and in some instances can be ignored, the authors believe that coil retrieval is indicated if a free end is seen pulsating along the blood flow stream to prevent migration of the entire coil mass. In one patient, a microballoon was inflated across the neck of the aneurysm during retrieval of a herniated coil to prevent further coil herniation from the aneurysm sac. We present two cases in which prolapsed coils were successfully retrieved either using a microsnare and balloon combination or a microsnare alone. This report focuses on the efficacy of the Amplatz microsnare for such retrievals and the circumstances in which a herniated coil needs to be retrieved. We report two cases in which embolization coils partially migrated into the parent artery during endovascular treatment of cerebral aneurysm and were retrieved using the Amplatz Nitinol microsnare. (orig.)

  7. Hydrodynamic studies of CNT nanofluids in helical coil heat exchanger

    Science.gov (United States)

    Babita; Sharma, S. K.; Mital Gupta, Shipra; Kumar, Arinjay

    2017-12-01

    Helical coils are extensively used in several industrial processes such as refrigeration systems, chemical reactors, recovery processes etc to accommodate a large heat transfer area within a smaller space. Nanofluids are getting great attention due to their enhanced heat transfer capability. In heat transfer equipments, pressure drop is one of the major factors of consideration for pumping power calculations. So, the present work is aimed to study hydrodynamics of CNT nanofluids in helical coils. In this study, pressure drop characteristics of CNT nanofluid flowing inside horizontal helical coils are investigated experimentally. The helical coil to tube diameter was varied from 11.71 to 27.34 keeping pitch of the helical coil constant. Double distilled water was used as basefluid. SDBS and GA surfactants were added to stablilize CNT nanofluids. The volumetric fraction of CNT nanofluid was varied from 0.003 vol% to 0.051 vol%. From the experimental data, it was analyzed that the friction factor in helical coils is greater than that of straight tubes. Concentration of CNT in nanofluids also has a significant influence on the pressure drop/friction factor of helical coils. At a constant concentration of CNT, decreasing helical coil to tube diameter from 27.24 to 11.71, fanning friction factor of helical coil; f c increases for a constant value of p/d t. This increase in the value of fanning friction factor can be attributed to the secondary flow of CNT nanofluid in helical coils.

  8. Transcranial Magnetic Stimulation-coil design with improved focality

    Science.gov (United States)

    Rastogi, P.; Lee, E. G.; Hadimani, R. L.; Jiles, D. C.

    2017-05-01

    Transcranial Magnetic Stimulation (TMS) is a technique for neuromodulation that can be used as a non-invasive therapy for various neurological disorders. In TMS, a time varying magnetic field generated from an electromagnetic coil placed on the scalp is used to induce an electric field inside the brain. TMS coil geometry plays an important role in determining the focality and depth of penetration of the induced electric field responsible for stimulation. Clinicians and basic scientists are interested in stimulating a localized area of the brain, while minimizing the stimulation of surrounding neural networks. In this paper, a novel coil has been proposed, namely Quadruple Butterfly Coil (QBC) with an improved focality over the commercial Figure-8 coil. Finite element simulations were conducted with both the QBC and the conventional Figure-8 coil. The two coil's stimulation profiles were assessed with 50 anatomically realistic MRI derived head models. The coils were positioned on the vertex and the scalp over the dorsolateral prefrontal cortex to stimulate the brain. Computer modeling of the coils has been done to determine the parameters of interest-volume of stimulation, maximum electric field, location of maximum electric field and area of stimulation across all 50 head models for both coils.

  9. Stress-strain effects in alumina-Cu reinforced Nb{sub 3}Sn wires fabricated by the tube process

    Energy Technology Data Exchange (ETDEWEB)

    Murase, Satoru; Nakayama, Shigeo; Masegi, Tamaki; Koyanagi, Kei; Nomura, Shunji [Toshiba Corp., Kawasaki, Kanagawa (Japan). Research and Development Center; Shiga, Noriyuki; Kobayashi, Norio; Watanabe, Kazuo

    1997-09-01

    In order to fabricate a large-bore, high-field magnet which achieves a low coil weight and volume, a high strength compound superconducting wire is required. For those demands we have developed the reinforced Nb{sub 3}Sn wire using alumina dispersion strengthened copper (alumina-Cu) as a reinforcement material and the tube process of the Nb{sub 3}Sn wire fabrication. The ductility study of the composites which consisted of the reinforcement, Nb tube, Cu, and Cu clad Sn brought a 1 km long alumina-Cu reinforced Nb{sub 3}Sn wire successfully. Using fabricated wires measurements and evaluations of critical current density as parameters of magnetic field, tensile stress, tensile strain, and transverse compressive stress, and those of stress-strain curves at 4.2 K were performed. They showed superior performance such as high 0.3% proof stress (240 MPa at 0.3% strain) and high maximum tolerance stress (320 MPa) which were two times as large as those of conventional Cu matrix Nb{sub 3}Sn wire. The strain sensitivity parameters were obtained for the reinforced Nb{sub 3}Sn wire and the Cu matrix one using the scaling law. Residual stress of the component materials caused by cooling down to 4.2 K from heat-treatment temperature was calculated using equivalent Young`s modulus, equivalent yield strength, thermal expansion coefficient and other mechanical parameters. Calculated stress-strain curves at 4.2 K for the reinforced Nb{sub 3}Sn wire and the Cu matrix one based on calculation of residual stress, had good agreement with the experimental values. (author)

  10. Field Quality and Alignment of the Series Produced Superconducting Matching Quadrupoles for the LHC Insertions

    CERN Document Server

    Catalan-Lasheras, Nuria; Kirby, Glyn; Ostojic, Ranko; Perez, Juan C; Prin, Herve

    2005-01-01

    The production of the superconducting quadrupoles for the LHC insertions is advancing well and about half of the magnets have been produced. The coil size and field measurements performed on individual magnets both in warm and cold conditions are yielding significant results. In this paper we present the procedures and results of steering the series production at the magnet manufacturers and the assembly of cold masses at CERN. In particular, we present the correlation between coil sizes and geometrical field errors, the effect of permeability of magnet collars, and the analysis of warm-cold correlations and hysteresis of the main field multipoles. The results are compared with the target values for field multipoles and quadrupole alignment.

  11. Type I macrophage scavenger receptor contains α-helical and collagen-like coiled coils

    Science.gov (United States)

    Kodama, Tatsuhiko; Freeman, Mason; Rohrer, Lucia; Zabrecky, James; Matsudaira, Paul; Krieger, Monty

    1990-02-01

    The macrophage scavenger receptor is a trimeric membrane glycoprotein with unusual ligand-binding properties which has been implicated in the development of atherosclerosis. The trimeric structure of the bovine type I scavenger receptor, deduced by complementary DNA cloning, contains three extracellular C-terminal cysteine-rich domains connected to the transmembrane domain by a long fibrous stalk. This stalk structure, composed of an a-helical coiled coil and a collagen-like triple helix, has not previously been observed in an integral membrane protein.

  12. "Cut wires grating – single longitudinal wire" planar metastructure to achieve microwave magnetic resonance in a single wire

    Directory of Open Access Journals (Sweden)

    G. Kraftmakher

    2012-09-01

    Full Text Available Here we present metastructures containing cut-wire grating and a single longitudinal cut-wire orthogonal to grating’s wires. Experimental investigations at microwaves show these structures can provide strong magnetic resonant response of a single nonmagnetic cut-wire in dependence on configuration and sizes in the case when metastructures are oriented along the direction of wave propagation and cut-wires of grating are parallel to the electric field of a plane electromagnetic wave. It is suggested a concept of magnetic response based on antiparallel resonant currents excited by magnetic field of surface polaritons in many spatial LC-circuits created from cut-wire pairs of a grating and section of longitudinal cut-wire. Three separately observed resonant effects connected with grating, LC-circuits and with longitudinal cut-wire have been identified applying measurements in waveguides, cutoff waveguides and free space. To tune and mark resonance split cut-wires are loaded with varactor diodes.

  13. A Vibrating Wire System For Quadrupole Fiducialization

    Energy Technology Data Exchange (ETDEWEB)

    Wolf, Zachary

    2010-12-13

    A vibrating wire system is being developed to fiducialize the quadrupoles between undulator segments in the LCLS. This note provides a detailed analysis of the system. The LCLS will have quadrupoles between the undulator segments to keep the electron beam focused. If the quadrupoles are not centered on the beam axis, the beam will receive transverse kicks, causing it to deviate from the undulator axis. Beam based alignment will be used to move the quadrupoles onto a straight line, but an initial, conventional alignment must place the quadrupole centers on a straight line to 100 {micro}m. In the fiducialization step of the initial alignment, the position of the center of the quadrupole is measured relative to tooling balls on the outside of the quadrupole. The alignment crews then use the tooling balls to place the magnet in the tunnel. The required error on the location of the quadrupole center relative to the tooling balls must be less than 25 {micro}m. In this note, we analyze a system under construction for the quadrupole fiducialization. The system uses the vibrating wire technique to position a wire onto the quadrupole magnetic axis. The wire position is then related to tooling balls using wire position detectors. The tooling balls on the wire position detectors are finally related to tooling balls on the quadrupole to perform the fiducialization. The total 25 {micro}m fiducialization error must be divided between these three steps. The wire must be positioned onto the quadrupole magnetic axis to within 10 {micro}m, the wire position must be measured relative to tooling balls on the wire position detectors to within 15 {micro}m, and tooling balls on the wire position detectors must be related to tooling balls on the quadrupole to within 10 {micro}m. The techniques used in these three steps will be discussed. The note begins by discussing various quadrupole fiducialization techniques used in the past and discusses why the vibrating wire technique is our method

  14. A review of 5434 percutaneous pediatric central venous catheters inserted by anesthesiologists.

    Science.gov (United States)

    Malbezin, Serge; Gauss, Tobias; Smith, Ian; Bruneau, Beatrice; Mangalsuren, Nyamjargal; Diallo, Thierno; Skhiri, Alia; Nivoche, Yves; Dahmani, Souhayl; Brasher, Christopher

    2013-11-01

    To review the results of an anesthesiologist led pediatric percutaneous central venous access service. Prospective data on percutaneous pediatric central venous catheter (CVC) insertions were collected over 22 years. Data included age, gender, weight, previous central CVCs, venous thromboses, investigations for great vein patency, type of CVC, external diameter, previous CVC insertions, intended use, operator identity, and the vein into which the CVC was inserted. The default technique was internal jugular vein cannulation using landmark technique (LT). Complication was defined as the following: failure to cannulate any vein, hemothorax, pneumothorax, right atrial perforation, extravenous wire positioning or CVC position and whether the patient was taken back to theater for CVC repositioning. Five thousand four hundred and thirty-four percutaneous CVC insertion procedures were performed on 3954 patients. One-third involved children <1 year of age (n = 1823: 34%). Five thousand one hundred and twenty-five CVCs (95.3%) were inserted into internal jugular veins. The majority were tunneled CVCs (n = 5190: 96.2%). The perioperative complication rate was 1.3%. Successful cannulation occurred in 99.5% of patients. Failure was more likely in children <3 kg, during large bore hemodialysis CVC insertions and during the first 4 years of the service - the latter suggesting a learning curve. Ninety-nine percent of CVCs were inserted using LTs. This study demonstrates a high success rate and low complication rate during pediatric percutaneous internal jugular vein CVC insertions by trained anesthesiologists using LTs. Smaller children, hemodialysis CVCs, and the team's learning curve were identified as risk factors for insertion failure. © 2013 John Wiley & Sons Ltd.

  15. Eddy Current Loss Induced in Aluminum Thermal Conduction Strips for ASPCS Coils Indirectly Cooled by Liquid Hydrogen through Thermo-siphon System

    Science.gov (United States)

    Ota, Narumi; Katsura, Masashi; Ando, Kennosuke; Takao, Tomoaki; Shintomi, Takakazu; Makida, Yasuhiro; Hamajima, Takataro; Tsuda, Makoto; Miyagi, Daisuke; Tsujigami, Hiroshi; Fujikawa, Shizuichi; Semba, Toshiaki; Iwaki, Katsuya

    To promote renewable energy sources, we proposed a new system called the Advanced Superconducting Power Conditioning System (ASPCS), which consists of Superconducting Magnetic Energy Storage-system (SMES), Electrolyzer, and Fuel Cell, and is also combined with a liquid hydrogen station for vehicles. The SMES plays a role to compensate the fast fluctuations generated by the renewable energies. In case of the ASPCS with a capacity of 5 MW, we designed the 50 MJ-class SMES composed of 4 solenoid coils. The winding of the solenoid coils is double pancake and a basic coil is 2 m in diameter and 0.5 m in height. Each SMES coil is wound with MgB2 conductor and indirectly cooled at 20 K by liquid hydrogen flowing through a thermo-siphon cooling system. Pure aluminum strips are inserted between the double-pancake coils and the pure aluminum plates gathering the strips lead to liquid hydrogen pipes. This scheme enables the strips and the plates to transfer the heat load in the coils to the cooling pipes and keep the coils at low temperature. On the other hand, we must consider that the strips generate eddy current loss which is strongly affected by a width of the strips. At the same time as the primary study of the SMES coils, we experimented on the thermo-siphon cooling system and investigated the relationship between the heat load and the heat extraction ability of the cooling system. The experiments showed that the cooling system could proficiently function. The estimation of eddy current loss from the particular cooling aluminum strips for the SMES in the ASPCS is reported with the results of the thermo-siphon driving experiment.

  16. Practical design of a 4 Tesla double-tuned RF surface coil for interleaved 1H and 23Na MRI of rat brain.

    Science.gov (United States)

    Alecci, M; Romanzetti, S; Kaffanke, J; Celik, A; Wegener, H P; Shah, N J

    2006-08-01

    MRI is proving to be a very useful tool for sodium quantification in animal models of stroke, ischemia, and cancer. In this work, we present the practical design of a dual-frequency RF surface coil that provides (1)H and (23)Na images of the rat head at 4 T. The dual-frequency RF surface coil comprised of a large loop tuned to the (1)H frequency and a smaller co-planar loop tuned to the (23)Na frequency. The mutual coupling between the two loops was eliminated by the use of a trap circuit inserted in the smaller coil. This independent-loop design was versatile since it enabled a separate optimisation of the sensitivity and RF field distributions of the two coils. To allow for an easy extension of this simple double-tuned coil design to other frequencies (nuclei) and dimensions, we describe in detail the practical aspects of the workbench design and MRI testing using a phantom that mimics in vivo conditions. A comparison between our independent-loop, double-tuned coil and a single-tuned (23)Na coil of equal size obtained with a phantom matching in vivo conditions, showed a reduction of the (23)Na sensitivity (about 28 %) because of signal losses in the trap inductance. Typical congruent (1)H and (23)Na rat brain images showing good SNR ((23)Na: brain 7, ventricular cerebrospinal fluid 11) and spatial resolution ((23)Na: 1.25 x 1.25 x 5mm(3)) are also reported. The in vivo SNR values obtained with this coil were comparable to, if not better than, other contemporary designs in the literature.

  17. Design and testing of a high voltage coil for the kicker magnets of CERN's Large Hadron Collider

    CERN Document Server

    Mayer, M; Schröder, G

    1996-01-01

    The Large Hadron Collider (LHC), the world¹s largest proton and lead-ion accelerator, is currently under construction at CERN, Geneva, Switzerland. To extract the particle beams at the end of a physics run and in emergency situations 2 beam abort systems, built of 14 fast high-power kicker magnets each, are required. These magnets will operate at 35 kV and 30 kA with a pulse length of 90 ms and a rise time of 3 ms. A prototype magnet with a single turn high voltage coil has been built and tested. The magnet closely surrounds a ceramic vacuum tube. In order to insert this beam pipe into the magnet, the coil and the magnet have to be built in two halves which can easily be separated. The paper describes the design principles of the high voltage coil, the different options for the coil insulation material, as well as details concerning the adopted manufacturing process. The paper also describes the extensive loss-factor measurements which have been carried out as part of the acceptance tests. Finally it repor...

  18. Analysis of alpha-helical coiled coils with the program TWISTER reveals a structural mechanism for stutter compensation.

    Science.gov (United States)

    Strelkov, Sergei V; Burkhard, Peter

    2002-01-01

    Alpha-helical coiled coils represent a widespread protein structure motif distinguished by a seven-residue periodicity of apolar residues in the primary sequence. A characteristic "knobs-into-holes" packing of these residues into a hydrophobic core results in a superhelical, usually left-handed, rope of two or more alpha-helices. Such a geometry can be parameterized. For this purpose, a new computer program, TWISTER, was developed. With the three-dimensional coordinates as input, TWISTER uses an original algorithm to determine the local coiled-coil parameters as a function of residue number. In addition, heptad positions are assigned based on structural criteria. It is known that frequently encountered discontinuities in the heptad repeat, such as stutters and skips, can be tolerated within a continuous coiled coil but result in a local distortion of its geometry. This was explored in detail with the help of TWISTER for several two- and three-stranded coiled coils. Depending on the particular protein, stutters were found to be compensated locally by an unwinding of the superhelix, alpha-helical unwinding, or both. In the first case, there is often a local switch from a left-handed to a right-handed superhelix. In general, the geometrical distortion is confined to about two alpha-helical turns at either side of the stutter. Furthermore, stutters result in a local increase of the coiled-coil radius. (c) 2002 Elsevier Science (USA).

  19. The heterotrimeric laminin coiled-coil domain exerts anti-adhesive effects and induces a pro-invasive phenotype.

    Directory of Open Access Journals (Sweden)

    Patricia Santos-Valle

    Full Text Available Laminins are large heterotrimeric cross-shaped extracellular matrix glycoproteins with terminal globular domains and a coiled-coil region through which the three chains are assembled and covalently linked. Laminins are key components of basement membranes, and they serve as attachment sites for cell adhesion, migration and proliferation. In this work, we produced a recombinant fragment comprising the entire laminin coiled-coil of the α1-, β1-, and γ1-chains that assemble into a stable heterotrimeric coiled-coil structure independently of the rest of the molecule. This domain was biologically active and not only failed to serve as a substrate for cell attachment, spreading and focal adhesion formation but also inhibited cell adhesion to laminin when added to cells in a soluble form at the time of seeding. Furthermore, gene array expression profiling in cells cultured in the presence of the laminin coiled-coil domain revealed up-regulation of genes involved in cell motility and invasion. These findings were confirmed by real-time quantitative PCR and zymography assays. In conclusion, this study shows for the first time that the laminin coiled-coil domain displays anti-adhesive functions and has potential implications for cell migration during matrix remodeling.

  20. Phosphorus in antique iron music wire.

    Science.gov (United States)

    Goodway, M

    1987-05-22

    Harpsichords and other wire-strung musical instruments were made with longer strings about the beginning of the 17th century. This change required stronger music wire. Although these changes coincided with the introduction of the first mass-produced steel (iron alloyed with carbon), carbon was not found in samples of antique iron harpsichord wire. The wire contained an amount of phosphorus sufficient to have impeded its conversion to steel, and may have been drawn from iron rejected for this purpose. The method used to select pig iron for wire drawing ensured the highest possible phosphorus content at a time when its presence in iron was unsuspected. Phosphorus as an alloying element has had the reputation for making steel brittle when worked cold. Nevertheless, in replicating the antique wire, it was found that lowcarbon iron that contained 0.16 percent phosphorus was easily drawn to appropriate gauges and strengths for restringing antique harpsichords.

  1. Electromagnetic Behaviour of Metallic Wire Structures

    CERN Document Server

    Chui, S T

    2013-01-01

    Despite the recent development and interest in the photonics of metallic wire structures, the relatively simple concepts and physics often remain obscured or poorly explained to those who do not specialize in the field. Electromagnetic Behaviour of Metallic Wire Structures provides a clear and coherent guide to understanding these phenomena without excessive numerical calculations.   Including both background material and detailed derivations of the various different formulae applied, Electromagnetic Behaviour of Metallic Wire Structures describes how to extend basic circuit theory relating to voltages, currents, and resistances of metallic wire networks to include situations where the currents are no longer spatially uniform along the wire. This lays a foundation for a deeper understanding of the many new phenomena observed in meta-electromagnetic materials.   Examples of applications are included to support this new approach making Electromagnetic Behaviour of Metallic Wire Structures a comprehensive and ...

  2. Comparison of the association of sac growth and coil compaction with recurrence in coil embolized cerebral aneurysms.

    Directory of Open Access Journals (Sweden)

    Anna L Hoppe

    Full Text Available In recurrent cerebral aneurysms treated by coil embolization, coil compaction is regarded as the presumptive mechanism. We test the hypothesis that aneurysm growth is the primary recurrence mechanism. We also test the hypothesis that the coil mass will translate a measurable extent when recurrence occurs.An objective, quantitative image analysis protocol was developed to determine the volumes of aneurysms and coil masses during initial and follow-up visits from 3D rotational angiograms. The population consisted of 15 recurrence and 12 non-recurrence control aneurysms initially completely coiled at a single center. An investigator sensitivity study was performed to assess the objectivity of the methods. Paired Wilcoxon tests (p<0.05, one-tailed were performed to assess for aneurysm and coil growth. The translation of the coil mass center at follow-up was computed. A Mann Whitney U-Test (p<0.05, one-tailed was used to compare translation of coil mass centers between recurrence and control subjects.Image analysis protocol was found to be insensitive to the investigator. Aneurysm growth was evident in the recurrence cohort (p=0.003 but not the control (p=0.136. There was no evidence of coil compaction in either the recurrence or control cohorts (recurrence: p=0.339; control: p=0.429. The translation of the coil mass centers was found to be significantly larger in the recurrence cohort than the control cohort (p=0.047.Aneurysm sac growth, not coil compaction, was the primary mechanism of recurrence following successful coil embolization. The coil mass likely translates to a measurable extent when recurrence occurs and has the potential to serve as a non-angiographic recurrence marker.

  3. Field gradient calculation of HTS double-pancake coils considering the slanted turns and the splice

    Energy Technology Data Exchange (ETDEWEB)

    Baek, Geon Woo; Kim, Jin Sub; Song, Seung Hyun; Ko, Tae Kuk [Yonsei University, Seoul (Korea, Republic of); Lee, Woo Seung [JH ENGINEERING CO., LTD., Gunpo (Korea, Republic of); Lee, On You [Korea National University of Transportation, Chungju (Korea, Republic of)

    2017-03-15

    To obtain Nuclear Magnetic Resonance (NMR) measurement of membrane protein, an NMR magnet is required to generate high intensity, homogeneity, and stability of field. A High-Temperature Superconducting (HTS) magnet is a promising alternative to a conventional Low-Temperature Superconducting (LTS) NMR magnet for high field, current density, and stability margin. Conventionally, an HTS coil has been wound by several winding techniques such as Single-Pancake (SP), Double-Pancake (DP), and layer-wound. The DP winding technique has been frequently used for a large magnet because long HTS wire is generally difficult to manufacture, and maintenance of magnet is convenient. However, magnetic field generated by the slanted turns and the splice leads to field inhomogeneity in Diameter of Spherical Volume (DSV). The field inhomogeneity degrades performance of NMR spectrometer and thus effect of the slanted turns and the splice should be analyzed. In this paper, field gradient of HTS double-pancake coils considering the slanted turns and the splice was calculated using Biot-Savart law and numerical integration. The calculation results showed that magnetic field produced by the slanted turns and the splice caused significant inhomogeneity of field.

  4. The properties of short-circuited HTSC coils

    Science.gov (United States)

    Kozintseva, M. V.; Bishaev, A. M.; Bush, A. A.; Gavrikov, M. B.; Kamentsev, K. E.; Nizhel'skii, N. A.; Savel'ev, V. V.; Sigov, A. S.

    2017-06-01

    The properties of short-circuited multiturn superconducting coils have been studied; coils with nonsuperconducting contacts have been fabricated from a high-temperature superconducting (HTSC) tape made by Super Power Company. The magnetic flux captured by HTSC coils has been measured at different values of magnetic field of the magnetizing solenoid. the critical current in the coils have been experimentally determined based on the maximum values of the field they captured. It is 50% of the nominal value for this HTSC tape. The range of external magnetic field, where HTSC coils keep the captured magnetic flux, has been experimentally found. The obtained results have demonstrated the possibility of designing magnet systems with levitating coils made of HTSC tape, in which levitation is controlled without using feedbacks.

  5. New method to design stellarator coils without the winding surface

    Science.gov (United States)

    Zhu, Caoxiang; Hudson, Stuart R.; Song, Yuntao; Wan, Yuanxi

    2018-01-01

    Finding an easy-to-build coils set has been a critical issue for stellarator design for decades. Conventional approaches assume a toroidal ‘winding’ surface, but a poorly chosen winding surface can unnecessarily constrain the coil optimization algorithm, This article presents a new method to design coils for stellarators. Each discrete coil is represented as an arbitrary, closed, one-dimensional curve embedded in three-dimensional space. A target function to be minimized that includes both physical requirements and engineering constraints is constructed. The derivatives of the target function with respect to the parameters describing the coil geometries and currents are calculated analytically. A numerical code, named flexible optimized coils using space curves (FOCUS), has been developed. Applications to a simple stellarator configuration, W7-X and LHD vacuum fields are presented.

  6. IEE wiring regulations explained and illustrated

    CERN Document Server

    Scaddan, Brian

    2013-01-01

    The IEE Wiring Regulations Explained and Illustrated, Second Edition discusses the recommendations of the IEE Regulations for the Electrical Equipment of Buildings for the safe selection or erection of wiring installations. The book emphasizes earthing, bonding, protection, and circuit design of electrical wirings. The text reviews the fundamental requirements for safety, earthing systems, the earth fault loop impedance, and supplementary bonding. The book also describes the different types of protection, such as protection against mechanical damage, overcurrent, under voltage (which prevents

  7. Radiofrequency Wire Recanalization of Chronically Thrombosed TIPS

    Energy Technology Data Exchange (ETDEWEB)

    Majdalany, Bill S., E-mail: bmajdala@med.umich.edu [University of Michigan Health System, Division of Interventional Radiology, Department of Radiology (United States); Elliott, Eric D., E-mail: eric.elliott@osumc.edu [The Ohio State University Wexner Medical Center, Division of Interventional Radiology, Department of Radiology (United States); Michaels, Anthony J., E-mail: Anthony.michaels@osumc.edu; Hanje, A. James, E-mail: James.Hanje@osumc.edu [The Ohio State University Wexner Medical Center, Division of Gastroenterology and Hepatology, Department of Medicine (United States); Saad, Wael E. A., E-mail: wsaad@med.umich.edu [University of Michigan Health System, Division of Interventional Radiology, Department of Radiology (United States)

    2016-07-15

    Radiofrequency (RF) guide wires have been applied to cardiac interventions, recanalization of central venous thromboses, and to cross biliary occlusions. Herein, the use of a RF wire technique to revise chronically occluded transjugular intrahepatic portosystemic shunts (TIPS) is described. In both cases, conventional TIPS revision techniques failed to revise the chronically thrombosed TIPS. RF wire recanalization was successfully performed through each of the chronically thrombosed TIPS, demonstrating initial safety and feasibility in this application.

  8. NEW DIRECTIONS IN THE ROLLED WIRE DEVELOPMENT

    Directory of Open Access Journals (Sweden)

    A. V. Vedeneev

    2004-01-01

    Full Text Available Analysis of the world practice and comparison with the competitors data shows, that for keeping up of RUP “BMZ'' competitiveness it is necessary to carry out works in directions of perfection of the steel wire cord production technology, development of steel wire cord, development of the breaker constructions with the high infiltration of rubber of wire with superstandard diameter and etc.

  9. Experimental setup to detect superconducting wire motion

    OpenAIRE

    K. Ruwali; A. Yamanaka; Y. Teramoto; K. Nakanishi; K. Hosoyama

    2009-01-01

    An experimental setup was designed and fabricated to study superconducting wire motion under the influence of electromagnetic force. Experiments were conducted at 4.2 K by varying the experimental conditions such as the tension to the superconducting wire and different insulating materials at the interface of the superconducting wire and head part. The insulating materials used in the experiments were polyimide film and a high strength polyethylene fiber cloth, Dyneema. Details of the experim...

  10. An electromagnetic micrometer to measure the wire centering in high- resolution aluminium drift tubes

    CERN Document Server

    Cambiaghi, M; Casani, S; Ferrari, R; Gaudio, G; Iuvino, G; Lanza, A; Prata, M J

    1999-01-01

    The muon detector of the Atlas experiment at LHC (CERN) consists of 370000 high-resolution drift tubes assembled in multi-layer chambers. To take full advantage of the single-tube resolution, the high- precision external surface of tube end-plugs is used for positioning a layer before gluing. The wire position in the tube is defined at construction time by means of a locator inserted in the end-plug. To check that the wire is in the nominal position after the tube assembly an electromagnetic micrometer (EMMI) has been developed. EMMI detects the wire position by measuring the electromotive force induced in two sensors symmetrically placed on both sides of the tube when a small sinusoidal current circulates on the wire. An accuracy of two microns on the wire centering has been obtained. The simplicity of this method and the short measuring time allow every drift tube to be checked, thus guaranteeing the precision requested for the Atlas muon detector. (4 refs).

  11. An electromagnetic micrometer to measure the wire centering in high-resolution aluminium drift tubes

    CERN Document Server

    Cambiaghi, M; Casani, S; Ferrari, R; Gaudio, G; Iuvino, G; Lanza, A; Prata, M J

    1999-01-01

    The muon detector of the Atlas experiment at LHC (CERN) consists of 370000 high-resolution drift tubes assembled in multi-layer chambers. To take full advantage of the single-tube resolution, the high- precision external surface of tube end-plugs is used for positioning a layer before gluing. The wire position in the tube is defined at construction time by means of a locator inserted in the end-plug. To check that the wire is in the nominal position after the tube assembly an electromagnetic micrometer (EMMI) has been developed. EMMI detects the wire position by measuring the electromotive force induced in two sensors symmetrically placed on both sides of the tube when a small sinusoidal current circulates on the wire. An accuracy of two microns on the wire centering has been obtained. The simplicity of this method and the short measuring time allow every drift tube to be checked, thus guaranteeing the precision requested for the Atlas muon detector. (4 refs).

  12. Sound Coiled-Tubing Drilling Practices

    Energy Technology Data Exchange (ETDEWEB)

    Williams, Thomas; Deskins, Greg (Maurer Technology Inc.); Ward, Stephen L. (Advantage Energy Services Ltd); Hightower, Mel

    2001-09-30

    This Coiled-Tubing Drilling (CTD) Sound Practices Manual provides tools needed by CTD engineers and supervisors to plan, design and perform safe, successful CTD operations. As emphasized throughout, both careful planning and attention to detail are mandatory for success. A bibliography of many useful CTD references is presented in Chapter 6. This manual is organized according to three processes: 1) Pre-Job Planning Process, 2) Operations Execution Process, and 3) Post-Job Review Process. Each is discussed in a logical and sequential format.

  13. Minimisation of the wire position uncertainties of the new CERN vacuum wire scanner

    CERN Document Server

    AUTHOR|(CDS)2069346; Barjau Condomines, A

    In the next years the luminosity of the LHC will be significantly increased. This will require a much higher accuracy of beam profile measurement than actually achievable by the current wire scanner. The new fast wire scanner is foreseen to measure small emittance beams throughout the LHC injector chain, which demands a wire travelling speed up to 20 ms-1 and position measurement accuracy of the order of a few microns. The vibrations of the mechanical parts of the system, and particularly the vibrations of the thin carbon wire, were identified as the major error sources of wire position uncertainty. Therefore the understanding of the wire vibrations is a high priority for the design and operation of the new device. This document presents the work performed to understand the main causes of the wire vibrations observed in one of the existing wire scanner and the new proposed design.

  14. Optically tracked, single-coil, scanning magnetic induction tomography

    Science.gov (United States)

    Feldkamp, Joe R.; Quirk, Stephen

    2017-03-01

    Recent work has shown the feasibility of single-coil, magnetic induction tomography, for visualizing a 3D distribution of electrical conductivity in portions of the human body. Loss is measured in a single, planar coil consisting of concentric circular loops while the coil is relocated to various non-redundant positions and orientations in the vicinity of the target. These loss values, together with measured coil position and orientation, are processed by a quantitative mapping equation that enables reconstruction of an electrical conductivity image. Up until now, the position of the coil had to be established by a template, which required assignment of locations for the coil to visit without necessarily giving any prior consideration to target geometry. We have now added optical tracking to our existing single-coil device so that position and orientation are tracked automatically, allowing collection of coil loss data at arbitrary positions or orientations as needed. Optical tracking is accomplished via a set of IR reflective spheres mounted on the same enclosure that supports the coil. Position for a select sphere within the set, together with the four quaternions specifying optical body orientation, is fed to a laptop at the same time coil loss data is streamed to the same laptop via Bluetooth. The coil center can be tracked with sub-millimeter accuracy while orientation angle is known to a fraction of a degree. This work illustrates the use of single-coil MIT in full, position-orientation-tracked scan mode while imaging laboratory phantoms. Phantoms are based upon simple materials having biologic conductivity (values for the various features within the image.

  15. Transmit coil design for Wireless Power Transfer for medical implants.

    Science.gov (United States)

    Lemdiasov, Rosti; Venkatasubramanian, Arun

    2017-07-01

    A new design approach for the design of transmit coils for Wireless Power Transfer (WPT) is presented. The theoretical formulation involves a figure of merit that has to be maximized to solve for the surface current. Numerical predictions and comparisons with practical measurements for the coil parameters (inductance. resistance) underscore the success of this approach in terms of achieving strong coupling with a receive coil while maintaining low resistance.

  16. Aircraft Wiring Support Equipment Integration Laboratory (AWSEIL)

    Data.gov (United States)

    Federal Laboratory Consortium — Purpose:The Aircraft Wiring Support Equipment Integration Laboratory (AWSEIL) provides a variety of research, design engineering and prototype fabrication services...

  17. submitter Dynamical Models of a Wire Scanner

    CERN Document Server

    Barjau, Ana; Dehning, Bernd

    2016-01-01

    The accuracy of the beam profile measurements achievable by the current wire scanners at CERN is limited by the vibrations of their mechanical parts. In particular, the vibrations of the carbon wire represent the major source of wire position uncertainty which limits the beam profile measurement accuracy. In the coming years, due to the Large Hadron Collider (LHC) luminosity upgrade, a wire traveling speed up to 20 $m s^{−1}$ and a position measurement accuracy of the order of 1 μm will be required. A new wire scanner design based on the understanding of the wire vibration origin is therefore needed. We present the models developed to understand the main causes of the wire vibrations observed in an existing wire scanner. The development and tuning of those models are based on measurements and tests performed on that CERN proton synchrotron (PS) scanner. The final model for the (wire + fork) system has six degrees-of-freedom (DOF). The wire equations contain three different excitation terms: inertia...

  18. An autoinhibited coiled-coil design strategy for split-protein protease sensors.

    Science.gov (United States)

    Shekhawat, Sujan S; Porter, Jason R; Sriprasad, Akshay; Ghosh, Indraneel

    2009-10-28

    Proteases are widely studied as they are integral players in cell-cycle control and apoptosis. We report a new approach for the design of a family of genetically encoded turn-on protease biosensors. In our design, an autoinhibited coiled-coil switch is turned on upon proteolytic cleavage, which results in the complementation of split-protein reporters. Utilizing this new autoinhibition design paradigm, we present the rational construction and optimization of three generations of protease biosensors, with the final design providing a 1000-fold increase in bioluminescent signal upon addition of the TEV protease. We demonstrate the generality of the approach utilizing two different split-protein reporters, firefly luciferase and beta-lactamase, while also testing our design in the context of a therapeutically relevant protease, caspase-3. Finally, we present a dual protease sensor geometry that allows for the use of these turn-on sensors as potential AND logic gates. Thus, these studies potentially provide a new method for the design and implementation of genetically encoded turn-on protease sensors while also providing a general autoinhibited coiled-coil strategy for controlling the activity of fragmented proteins.

  19. Structure and Misfolding of the Flexible Tripartite Coiled-Coil Domain of Glaucoma-Associated Myocilin

    Energy Technology Data Exchange (ETDEWEB)

    Hill, Shannon E.; Nguyen, Elaine; Donegan, Rebecca K.; Patterson-Orazem, Athéna C.; Hazel, Anthony; Gumbart, James C.; Lieberman, Raquel L.

    2017-11-01

    Glaucoma-associated myocilin is a member of the olfactomedins, a protein family involved in neuronal development and human diseases. Molecular studies of the myocilin N-terminal coiled coil demonstrate a unique tripartite architecture: a Y-shaped parallel dimer-of-dimers with distinct tetramer and dimer regions. The structure of the dimeric C-terminal 7-heptad repeats elucidates an unexpected repeat pattern involving inter-strand stabilization by oppositely charged residues. Molecular dynamics simulations reveal an alternate accessible conformation in which the terminal inter-strand disulfide limits the extent of unfolding and results in a kinked configuration. By inference, full-length myocilin is also branched, with two pairs of C-terminal olfactomedin domains. Selected variants within the N-terminal region alter the apparent quaternary structure of myocilin but do so without compromising stability or causing aggregation. In addition to increasing our structural knowledge of naturally occurring extracellular coiled coils and biomedically important olfactomedins, this work broadens the scope of protein misfolding in the pathogenesis of myocilin-associated glaucoma.

  20. Structure and Misfolding of the Flexible Tripartite Coiled-Coil Domain of Glaucoma-Associated Myocilin.

    Science.gov (United States)

    Hill, Shannon E; Nguyen, Elaine; Donegan, Rebecca K; Patterson-Orazem, Athéna C; Hazel, Anthony; Gumbart, James C; Lieberman, Raquel L

    2017-11-07

    Glaucoma-associated myocilin is a member of the olfactomedins, a protein family involved in neuronal development and human diseases. Molecular studies of the myocilin N-terminal coiled coil demonstrate a unique tripartite architecture: a Y-shaped parallel dimer-of-dimers with distinct tetramer and dimer regions. The structure of the dimeric C-terminal 7-heptad repeats elucidates an unexpected repeat pattern involving inter-strand stabilization by oppositely charged residues. Molecular dynamics simulations reveal an alternate accessible conformation in which the terminal inter-strand disulfide limits the extent of unfolding and results in a kinked configuration. By inference, full-length myocilin is also branched, with two pairs of C-terminal olfactomedin domains. Selected variants within the N-terminal region alter the apparent quaternary structure of myocilin but do so without compromising stability or causing aggregation. In addition to increasing our structural knowledge of naturally occurring extracellular coiled coils and biomedically important olfactomedins, this work broadens the scope of protein misfolding in the pathogenesis of myocilin-associated glaucoma. Copyright © 2017 Elsevier Ltd. All rights reserved.

  1. Deformable 3D-2D registration for guiding K-wire placement in pelvic trauma surgery

    Science.gov (United States)

    Goerres, J.; Jacobson, M.; Uneri, A.; de Silva, T.; Ketcha, M.; Reaungamornrat, S.; Vogt, S.; Kleinszig, G.; Wolinsky, J.-P.; Osgood, G.; Siewerdsen, J. H.

    2017-03-01

    Pelvic Kirschner wire (K-wire) insertion is a challenging surgical task requiring interpretation of complex 3D anatomical shape from 2D projections (fluoroscopy) and delivery of device trajectories within fairly narrow bone corridors in proximity to adjacent nerves and vessels. Over long trajectories ( 10-25 cm), K-wires tend to curve (deform), making conventional rigid navigation inaccurate at the tip location. A system is presented that provides accurate 3D localization and guidance of rigid or deformable surgical devices ("components" - e.g., K-wires) based on 3D-2D registration. The patient is registered to a preoperative CT image by virtually projecting digitally reconstructed radiographs (DRRs) and matching to two or more intraoperative x-ray projections. The K-wire is localized using an analogous procedure matching DRRs of a deformably parametrized model for the device component (deformable known-component registration, or dKC-Reg). A cadaver study was performed in which a K-wire trajectory was delivered in the pelvis. The system demonstrated target registration error (TRE) of 2.1 ± 0.3 mm in location of the K-wire tip (median ± interquartile range, IQR) and 0.8 ± 1.4º in orientation at the tip (median ± IQR), providing functionality analogous to surgical tracking / navigation using imaging systems already in the surgical arsenal without reliance on a surgical tracker. The method offers quantitative 3D guidance using images (e.g., inlet / outlet views) already acquired in the standard of care, potentially extending the advantages of navigation to broader utilization in trauma surgery to improve surgical precision and safety.

  2. A new stellarator coil design tool using space curves

    Science.gov (United States)

    Zhu, Caoxiang; Hudson, Stuart; Breslau, Joshua; Lazerson, Samuel; Song, Yuntao; Wan, Yuanxi

    2016-10-01

    Finding easy-to-build coils has always been critical for stellarator design. Conventional approaches assume a toroidal ``winding'' surface. Either a surface current potential is constructed using a Green's function; or a discrete set of filamentary coils lying on the winding surface is non-linearly optimized. The winding surface concept ensures that the coils are separated from the plasma surface; however, requiring the coils lie on a given winding surface may overly constrain the coil optimization process. In this work, we investigate whether a winding surface is required. Our starting point is to represent each discrete coil as an arbitrary closed curve embedded in 3D space. From the Fundamental Theorem for Curves, such curves are uniquely described by the curvature and torsion functions. Our representation does not need a winding surface and can allow coils to evolve arbitrarily. We have constructed different penalty functions, F, that incorporate both the `physics' and `engineering' constraints. The first and second derivatives of F with respect to the parameters describing the coils are constructed analytically and are exploited to enable fast optimization algorithms for finding minima. Illustrations of coils for W7X and other stellarators will be presented. China Scholarship Council.

  3. Stabilization of Tokamak Plasmas by the Addition of Nonaxisymmetric Coils

    Science.gov (United States)

    Reiman, Allan

    2008-11-01

    It has been recognized since the early days of the fusion program that stellarator coils can be used to stabilize current carrying, toroidal, magnetically confined plasmas.[1] More recently, it has been shown that the vertical mode in a tokamak can be stabilized by a relatively simple set of parallelogram-shaped, localized, nonaxisymmetric coils.[2] We show that by superposing sets of these parallelogram-shaped, nonaxisymmetric coils at different locations, it is possible to reproduce the coil current patterns for conventional stellarator coils as well as those for Furth-Hartman coils[3]. This allows us to gain insight into the physics of stabilization produced by various sets of nonaxisymmetric coils by analysis of the effect on stability of localized coils at differing locations. In particular, the relationship between the stabilization effect and the rotational transform generated by the nonaxisymmetric coils is clarified. [1] J. L. Johnson, C. R. Oberman, R. M. Kulsrud, and E. A. Frieman, Phys. Fluids 1, 281 (1958) [2] A. Reiman, Phys. Rev. Lett. 99, 135007, (2007). [3] H.P. Furth and C.W. Hartman, Phys. Fluids 11, 408 (1968).

  4. FE modeling of Cu wire bond process and reliability

    NARCIS (Netherlands)

    Yuan, C.A.; Weltevreden, E.R.; Akker, P. van den; Kregting, R.; Vreugd, J. de; Zhang, G.Q.

    2011-01-01

    Copper based wire bonding technology is widely accepted by electronic packaging industry due to the world-wide cost reduction actions (compared to gold wire bond). However, the mechanical characterization of copper wire differs from the gold wire; hence the new wire bond process setting and new bond

  5. Modeling the Insertion Mechanics of Flexible Neural Probes Coated with Sacrificial Polymers for Optimizing Probe Design

    Directory of Open Access Journals (Sweden)

    Sagar Singh

    2016-03-01

    Full Text Available Single-unit recording neural probes have significant advantages towards improving signal-to-noise ratio and specificity for signal acquisition in brain-to-computer interface devices. Long-term effectiveness is unfortunately limited by the chronic injury response, which has been linked to the mechanical mismatch between rigid probes and compliant brain tissue. Small, flexible microelectrodes may overcome this limitation, but insertion of these probes without buckling requires supporting elements such as a stiff coating with a biodegradable polymer. For these coated probes, there is a design trade-off between the potential for successful insertion into brain tissue and the degree of trauma generated by the insertion. The objective of this study was to develop and validate a finite element model (FEM to simulate insertion of coated neural probes of varying dimensions and material properties into brain tissue. Simulations were performed to predict the buckling and insertion forces during insertion of coated probes into a tissue phantom with material properties of brain. The simulations were validated with parallel experimental studies where probes were inserted into agarose tissue phantom, ex vivo chick embryonic brain tissue, and ex vivo rat brain tissue. Experiments were performed with uncoated copper wire and both uncoated and coated SU-8 photoresist and Parylene C probes. Model predictions were found to strongly agree with experimental results (<10% error. The ratio of the predicted buckling force-to-predicted insertion force, where a value greater than one would ideally be expected to result in successful insertion, was plotted against the actual success rate from experiments. A sigmoidal relationship was observed, with a ratio of 1.35 corresponding to equal probability of insertion and failure, and a ratio of 3.5 corresponding to a 100% success rate. This ratio was dubbed the “safety factor”, as it indicated the degree to which the coating

  6. THERMO-MECHANICALLY PROCESSED ROLLED WIRE FOR HIGH-STRENGTH ON-BOARD WIRE

    Directory of Open Access Journals (Sweden)

    V. A. Lutsenko

    2011-01-01

    Full Text Available It is shown that at twisting of wire of diameter 1,83 mm, produced by direct wire drawing of thermomechanically processed rolled wire of diameter 5,5 mm of steel 90, metal stratification is completely eliminated at decrease of carbon, manganese and an additional alloying of chrome.

  7. Finite element analysis on the wire breaking rule of 1×7IWS steel wire rope

    Directory of Open Access Journals (Sweden)

    Wenzheng Du

    2017-01-01

    Full Text Available Taking the wire rope of 1×7+IWS structure as the research object, the influences of the number of broken wires on the stress distribution under the same axial load were simulated and analysed, and it also explored the rule of wire breaking of steel wire ropes. Based on the SolidWorks software, the three-dimensional model of the wire rope was established. Importing the model into the ABAQUS, the finite element model of the steel wire rope was established. Firstly 5000 N axial tension was placed on the rope, the stress distribution was simulated and analysed, and the steel wire with the largest stress distribution was found out. Then one steel wire was truncated with the load unchanged, and the finite element simulation was carried out again, and repeated the steps several times. The results show that, with the increase of the number of broken wires, the Von-Mises stress of the wire rope increases sharply, and the stress distribution is concentrated on the rest of the unbroken wires, which brings great challenges to the safety of the wire rope.

  8. Design of Tunnel Magnetoresistive-Based Circular MFL Sensor Array for the Detection of Flaws in Steel Wire Rope

    Directory of Open Access Journals (Sweden)

    Liu Xiucheng

    2016-01-01

    Full Text Available Tunnel magnetoresistive (TMR devices have superior performances in weak magnetic field detection. In this study, TMR devices were first employed to form a circular magnetic flux leakage (MFL sensor for slight wire rope flaw detection. Two versions of this tailor-made circular TMR-based sensor array were presented for the inspection of wire ropes with the diameters of 14 mm and 40 mm, respectively. Helmholtz-like coils or a ferrite magnet-based magnetizer was selected to provide the proper magnetic field, in order to meet the technical requirements of the TMR devices. The coefficient of variance in the flaw detection performance of the sensor array elements was experimentally estimated at 4.05%. Both versions of the MFL sensor array were able to detect multiple single-broken wire flaws in the wire ropes. The accurate axial and circumferential positions of these broken wire flaws were estimated from the MFL scanning image results. In addition, the proposed TMR-based sensor array was applied to detect the MFL signal induced by slight surface wear defects. A mutual correlation analysis method was used to distinguish the signals caused by the lift-off fluctuation from the MFL scanning image results. The MFL sensor arrays presented in this study provide inspiration for the designing of tailor-made TMR-based circular sensor arrays for cylindrical ferromagnetic structural inspections.

  9. Design of a superconducting insert to obtain a high and quasi-uniform magnetic force field

    Energy Technology Data Exchange (ETDEWEB)

    Leveque, Jean [GREEN, University of Nancy BP 239, 54506 Vandoeuvre (France); Netter, Denis [GREEN, University of Nancy BP 239, 54506 Vandoeuvre (France); Quettier, Lionel [DAPNIA, CEA Saclay (France); Mailfert, Alain [INPL, 2 av de la foret de Haye, 54516 Vandoeuvre (France)

    2005-10-01

    In this paper, we study the magnetic force generated by the combination of a solenoid and a superconducting ring insert. We have focused our study on the uniformity of the magnetic force. We use a genetic algorithm to determine the optimal shape of the superconducting ring. We are able to obtain uniformity of 0.5% variance. We also study the influence of several factors on uniformity, such as the critical current of the coil, the ring, and the size of the working area.

  10. Production and measurement of the MQXA series of LHC low- beta insertion quadrupoles

    CERN Document Server

    Yamamoto, A; Fujii, T; Hashiguchi, E; Higashi, N; Iida, M; Kanahara, T; Kimura, N; Murai, S; Nakamoto, T; Odajima, W; Ogitsu, T; Ohhata, K; Ohuchi, N; Orikasa, T; Shintomi, T; Sugawara, S; Sugita, K; Tanaka, K; Terashima, A; Tsuchiya, K

    2005-01-01

    The inner triplet quadrupole magnets (MQXA) for the LHC low-beta insertion have been developed. The quadrupoles provide a field gradient of 215 T/m at 1.9 K in a coil aperture of 70 mm diameter and with an effective magnetic length of 6.37 m. The series of 20 magnets have been produced in industry, and full testing has been done at KEK. We present an overview of the production and the results from mechanical and magnetic measurements.

  11. Testing of the large bore single aperture 1-meter superconducting dipoles made with phenolic inserts

    CERN Document Server

    Boschmann, H; Dubbeldam, R L; Kirby, G A; Lucas, J; Ostojic, R; Russenschuck, Stephan; Siemko, A; Taylor, T M; Vanenkov, I; Weterings, W

    1998-01-01

    Two identical single aperture 1-metre superconducting dipoles have been built in collaboration with HMA Power Systems and tested at CERN. The 87.8 mm aperture magnets feature a single layer coil wound using LHC main dipole outer layer cable, phenolic spacer type collars, and a keyed two part structural iron yoke. The magnets are designed as models of the D1 separation dipole in the LHC experimental insertions, whose nominal field is 4.5 T at 4.5 K. In this report we present the test results of the two magnets at 4.3 K and 1.9 K.

  12. Dental MRI using wireless intraoral coils

    Science.gov (United States)

    Ludwig, Ute; Eisenbeiss, Anne-Katrin; Scheifele, Christian; Nelson, Katja; Bock, Michael; Hennig, Jürgen; von Elverfeldt, Dominik; Herdt, Olga; Flügge, Tabea; Hövener, Jan-Bernd

    2016-03-01

    Currently, the gold standard for dental imaging is projection radiography or cone-beam computed tomography (CBCT). These methods are fast and cost-efficient, but exhibit poor soft tissue contrast and expose the patient to ionizing radiation (X-rays). The need for an alternative imaging modality e.g. for soft tissue management has stimulated a rising interest in dental magnetic resonance imaging (MRI) which provides superior soft tissue contrast. Compared to X-ray imaging, however, so far the spatial resolution of MRI is lower and the scan time is longer. In this contribution, we describe wireless, inductively-coupled intraoral coils whose local sensitivity enables high resolution MRI of dental soft tissue. In comparison to CBCT, a similar image quality with complementary contrast was obtained ex vivo. In-vivo, a voxel size of the order of 250•250•500 μm3 was achieved in 4 min only. Compared to dental MRI acquired with clinical equipment, the quality of the images was superior in the sensitive volume of the coils and is expected to improve the planning of interventions and monitoring thereafter. This method may enable a more accurate dental diagnosis and avoid unnecessary interventions, improving patient welfare and bringing MRI a step closer to becoming a radiation-free alternative for dental imaging.

  13. A novel method for coiled tubing installation

    Energy Technology Data Exchange (ETDEWEB)

    Simpson, Peter J. [2H Offshore, Houston, TX (United States); Tibbetts, David [Aquactic Engineering and Construction Ltd., Aberdeen (United Kingdom)

    2009-12-19

    Installation of flexible pipe for offshore developments is costly due to the physical cost of the flexible pipe, expensive day rates and the availability of suitable installation vessels. Considering the scarcity of flexible pipe in today's increasingly demanding and busy market, operators are seeking a cost effective solution for installing piping in a range of water depths using vessels which are readily on hand. This paper describes a novel approach to installing reeled coiled tubing, from 1 inch to 5 inch diameter, from the back of a small vessel in water depths from 40 m up to around 1000 m. The uniqueness of the system is the fact that the equipment design is modular and compact. This means that when disassembled, it fits into standard 40 ft shipping containers, and the size allows it to be installed on even relatively small vessels of opportunity, such as anchor handling or installation vessels, from smaller, and cheaper quay side locations. Such an approach is the ideal solution to the problem faced by operators, in that it allows the installation of cheaper, readily available coiled tubing, from cost-effective vessels, which do not need to transit to a pick up the system. (author)

  14. Voice Coil Actuators for two MTG Instruments

    Science.gov (United States)

    Bencheikh, N.; Guignabert, A.; Barillot, F.; Benoit, C.; Burgui, C.; Compostizo, C.; Bueno, I.; Spanoudakis, P.; Kiener, L.; Schwab, P.

    2015-09-01

    While Cedrat Technologies has been active in space for more than 20 years with piezoelectric mechanisms, we have also been increasingly involved over the last few years in the development of magnetic actuators for space projects. In this paper, a focus is made on the case of magnetic actuators that are developed in the frame of the Meteosat Third Generation (MTG) project. The first one is the Scan Assembly (SCA) actuated by Rotating Voice Coil Motors (RVCM) for the East/West (E/W) axes and the North/South (N/S) axes developed in collaboration with Sener and the second one is the Voice Coil Motor (VCM) developed in collaboration with CSEM for the Corner Cube Mechanism (CCM)The motion needs are different for the both motor, linear motion for the CCM and rotational movement for the SCA. Even if the motion is different, the both applications have the same performance requirements such as linearity, low hysteresis, a high power to mass ratio, redundancy and so on.

  15. Umbilical cord coiling index and perinatal outcome.

    Science.gov (United States)

    Patil, Nivedita S; Kulkarni, Sunanda R; Lohitashwa, Renu

    2013-08-01

    To evaluate the perinatal outcome with the abnormal umbilical cord coiling index. This prospective study was carried out in the department of OBG at Adichunchangiri Institute of Medical Sciences, B.G.Nagara, Mandya, Karnataka, India from January 2008 to August 2010. 200 patients who were in active labour with term gestations, irrespective of their parities, who had singleton pregnancies with live babies who were either delivered by vaginal or LSCS were included in the study. Umbilical cord coiling index was calculated and it was correlated with various perinatal parameters like birth weight, meconium stained liquor, Apgar score, ponderal index and foetal growth restriction. Chi square and Fisher exact tests were used to find the significance of study parameters. There was a significant correlation between the hypercoiled cords (UCI >90(th) percentile) and IUGR of the babies (p value of UCI which was UCI which was > 90(th) percentile was associated with IUGR and low ponderal indices. Hypocoiled cords or UCI which was <10th percentile was associated with meconium staining, Apgar score at 1 min of <4 and at 5 min of <7, more LSCS rates and more NICU admissions.

  16. The Eulerian buckling test for orthodontic wires.

    Science.gov (United States)

    De Santis, R; Dolci, F; Laino, A; Martina, R; Ambrosio, L; Nicolais, L

    2008-04-01

    Orthodontic treatment is mainly dependent on the loads developed by metal wires. The load developed by a buckled orthodontic wire is of great concern for molar distalization and cannot be simply derived from mechanical properties measured through classical tests (i.e. tensile, torsion, and bending). A novel testing method, based on the Eulerian approach of a simple supported beam, has been developed in order to measure the load due to buckling of orthodontic wires. Elastic titanium molybdenum alloy (TMA; SDS Ormco) and superelastic Nitinol (3M Unitek) and copper nickel-titanium (NiTi; SDS Ormco) wires, each having a rectangular cross section of 0.016 x 0.022 square inches (0.41 x 0.56 mm(2)), were used. The wires were activated and deactivated by loading and unloading. In order to analyse thermo-mechanical properties in buckling, mechanical tests were assisted by calorimetric measurements through differential scanning calorimetry (DSC). Statistical analysis to determine differences between the samples was undertaken using two-way analysis of variance (ANOVA) and Tukey's post hoc test, and one-way ANOVA to assess differences between the tested wires under similar conditions and different materials. The results suggest that the load due to buckling depends on material composition, wire length, the amount of activation, temperature, and deformation rate. The results can be considered as the lower bound for the loads experienced by teeth as far as a buckled wire is concerned. At a temperature higher than the austenite finish transition temperature, superelastic wires were strongly dependent on temperature and deformation rate. The effect due to an increase of deformation rate was similar to that of a decrease of temperature. Load variations due to temperature of a superelastic wire with a length of 20 mm were estimated to be approximately 4 g/degrees C. The high performance of an applied superelastic wire may be related to the high dynamics of the load in relation to

  17. Introduction of a coiled solid-phase microextraction fiber based on a coating of animal bone waste for chromatographic analysis.

    Science.gov (United States)

    Razmi, Habib; Farrokhzadeh, Samaneh

    2017-04-01

    We attempt to introduce animal bone waste as a coating material with an organic-inorganic structure for the fabrication of a coiled solid-phase microextraction fiber for the first time. The coiled fiber was simply prepared with the use of copper wire and coated with bone waste suspension through the dip-coating method. The bone waste coating was characterized by scanning electron microscopy, Fourier transform infrared spectroscopy, and X-ray diffraction analysis. It was applied as new type of solid-phase microextraction fiber for preconcentration of polycyclic aromatic hydrocarbons before determination by high-performance liquid chromatography with UV detection. A wide linear range 0.01-99.0 μg/L and limits of detection in the range 3.0-11.1 ng/L were obtained at optimized conditions. The bone waste coated coiled solid-phase microextraction fiber has promise in sample preparation techniques because it is cost effective, available, stable in aqueous and organic solutions, environmentally friendly, and easy to fabricate and operate. © 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  18. Using the integral equations method to model a 2G racetrack coil with anisotropic critical current dependence

    Science.gov (United States)

    Martins, F. G. R.; Sass, F.; Barusco, P.; Ferreira, A. C.; de Andrade, R., Jr.

    2017-11-01

    Second-generation (2G) superconducting wires have already proved their potential in several applications. These materials have a highly nonlinear behavior that turns an optimized engineering project into a challenge. Between several numerical techniques that can be used to perform this task, the integral equations (IE) method stands out for avoiding mesh problems by representing the 2G wire cross-sectional area by a line. While most applications need to be represented in a 3D geometry, the IE is limited to longitudinal or axisymmetric models. This work demonstrates that a complex 3D geometry can be modeled by several coupled simulations using the IE method. In order to prove this statement, the proposed technique was used to simulate a 2G racetrack coil considering the self-field magnitude (B) and incidence angle (θ) on the tape. The J c characteristic was modeled in terms of parallel and normal to the tape plane magnetic field components (J c(B ∥ , B ⊥)) obtained from a V–I(B, θ) characterization of a tape segment. This result was implemented using commercial software with both A–V (vector magnetic potential and scalar voltage potential) and IE coupled simulations solved by finite elements. This solution bypasses the meshing problem due to the tapes slim geometry, considering each turn a single 1D model, all magnetically interacting in two 2D models. The simulations results are in good agreement to what was both expected and observed in the literature. The simulation is compared to the measured V–I characteristic for a single pancake racetrack coil built with same geometry as its simulation models, and a theoretical study demonstrates the possibilities of the proposed tool for analyzing a racetrack coil current density and electric field behavior in each of its turns.

  19. Mars Observer Orbit Insertion Briefing

    Science.gov (United States)

    1993-01-01

    Steve Wall is the host of this video entitled, "Return to the Red Planet". Live animation of the Mars Observer orbiting Mars is presented. Steve Wall explains the spacecraft insertion maneuver and also explains the purpose for the Mars Observer launch. Live coverage of the Cape Canaveral launch of the Mars Observer is also presented. Suzanne Dodd, Chief of the Mission Planning team describes the burn start and how the spacecraft will be captured by Mars' gravity. Glenn Cunningham, Mars Observer Project Manager, gives background information on the Mars Observer and describes the organizations behind the Mars Observer Spacecraft, such as the Deep Space Network, the Mission Operation Support Office, Science Investigators, the Flight Engineering Office, Operations Office, and the Ground Data System Office. Dr. William Piotrowski, Acting Director, Solar System Exploration Division, NASA, talks about the purpose of the Mars Pathfinder which is to develop the technology and systems for landing small science packages on Mars. Mr. Roger Gibbs, Former Mars Observer Spacecraft Systems Engineer, tells us how the Mars Observer was built and describes the structural elements on the Mars Observer. The 11-month cruise period for the spacecraft is given by Joseph Beerer, Manager of the Engineering office. The thrust for the Mars Orbit Insertion is described by Ronald Klemetson, Technical Manager, Propulsion Subsystem Jet Propulsion Laboratory (JPL). George Chen, Lead Engineer Attitude and Articulation Subsystem Spacecraft Team, explains the importance of the attitude control engines on the Spacecraft. Marvin Traxler, Manager of Tracking and Data Acquisition, describes how searching for a signal from the Mars Observer works. See NONP-NASA-VT-2000081555 for a continuation of this discussion with Marvin Traxler.

  20. Optical cochlear implant: evaluation of insertion forces of optical fibres in a cochlear model and of traumata in human temporal bones.

    Science.gov (United States)

    Balster, Sven; Wenzel, Gentiana I; Warnecke, Athanasia; Steffens, Melanie; Rettenmaier, Alexander; Zhang, Kaiyin; Lenarz, Thomas; Reuter, Guenter

    2014-02-01

    Optical stimulation for hearing restoration is developing as an alternative therapy to electrical stimulation. For a more frequency-specific activation of the auditory system, light-guiding fibres need to be inserted into the coiled cochlea. To enable insertion with minimal trauma, glass fibres embedded in silicone were used as models. Thus, glass fibres of varying core/cladding diameter with and without silicon coating (single as well as in bundles) were inserted into a human scala tympani (ST) model. Insertion cochlear model force measurements were performed, and the thinner glass fibres that showed low insertion forces in the model were inserted into cadaveric human temporal bones. Silicone-coated glass fibres with different core/cladding diameters and bundle sizes could be inserted up to a maximum depth of 20 mm. Fibres with a core/cladding diameter of 50/55 μm break during insertion deeper than 7-15 mm into the ST model, whereas thinner fibres (20/25 μm) could be inserted in the model without breakage and in human temporal bones without causing trauma to the inner ear structures. The insertion forces of silicone-coated glass fibres are comparable to those measured with conventional cochlear implant (CI) electrodes. As demonstrated in human temporal bones, a minimal traumatic implantation of an optical CI may be considered feasible.

  1. Wire grid and wire scanner design for the CERN Linac4

    CERN Document Server

    Roncarolo, F; Cheymol, B; Dutriat, C; Duraffourg, M; Focker, G J; Raich, U; Vuitton, C

    2010-01-01

    As part of the CERN LHC injector chain upgrade, LINAC4 [1] will accelerate H- ions from 45 KeV to 160 MeV. A number of wire grids and wire scanners will be used to characterize the beam transverse profile. This paper covers all monitor design aspects intended to cope with the required specifications. In particular, the overall measurement robustness, accuracy and sensitivity must be satisfied for different commissioning and operational scenarios. The physics mechanisms generating the wire signals and the wire resistance to beam induced thermal loads have been considered in order to determine the most appropriate monitor design in terms of wire material and dimensions.

  2. Steer-by-wire innovations and demonstrator

    NARCIS (Netherlands)

    Lupker, H.A.; Zuurbier, J.; Verschuren, R.M.A.F.; Jansen, S.T.H.; Willemsen, D.M.C.

    2002-01-01

    Arguments for 'by-wire' systems include production costs, packaging and traffic safety. Innovations concern both product and development process e.g. combined virtual engineering and Hardware-in-the-loop testing. Three Steer-by-wire systems are discussed: a steering system simulator used as a

  3. Add-On Shielding for Unshielded Wire

    Science.gov (United States)

    Koenig, J. C.; Billitti, J. W.; Tallon, J. M.

    1983-01-01

    Fabrication sequence used to produce compact shields slipped into place from free ends of wires already soldered into connectors at other ends. Single shields are formed into harnesses by connecting grounding jumpers. Technique is especially useful for small diameter wire attached to microminiature connectors.

  4. WIRED magazine announces rave awards nominees

    CERN Multimedia

    2002-01-01

    WIRED Magazine has anounced the nominees for its fourth annual WIRED Rave Awards, celebrating innovation and the individuals transforming commerce and culture. Jeffrey Hangst of the University of Aarhus has been nominated in the science category, for his work on the ATHENA Experiment, CERN (1/2 page).

  5. Kirschner Wire Breakage during Removal Requiring Retrieval

    Directory of Open Access Journals (Sweden)

    Kai Yuen Wong

    2016-01-01

    Full Text Available Kirschner wires (K-wires are widely used for fixation of fractures and dislocations in the hand as they are readily available, reliable, and cost-effective. Complication rates of up to 18% have been reported. However, K-wire breakage during removal is rare. We present one such case illustrating a simple technique for retrieval. A 35-year-old male presented with a distal phalanx fracture of his right middle finger. This open fracture was treated with K-wire fixation. Postoperatively, he developed a pin site infection with associated finger swelling. The K-wire broke during removal with the proximal piece completely retained in his middle phalanx. To minimise risk of osteomyelitis, the K-wire was removed with a novel surgical technique. He had full return of hand function. Intraoperative K-wire breakage has a reported rate of 0.1%. In our case, there was no obvious cause of breakage and the patient denied postoperative trauma. On the other hand, pin site infections are much more common with reported rates of up to 7% in the hand or wrist. K-wire fixation is a simple method for bony stabilisation but can be a demanding procedure with complications often overlooked. It is important to be aware of the potential sequelae.

  6. Emulating Wired Backhaul with Wireless Network Coding

    DEFF Research Database (Denmark)

    Thomsen, Henning; De Carvalho, Elisabeth; Popovski, Petar

    2014-01-01

    , the uplink traffic to the user, remains identical to the one performed in a wired system. In the broadcast phase, the decoding of the downlink traffic can also be guaranteed to remain identical. Hence, our solution claims an emulation of a wired backhaul with wireless network coding with same performance. We...

  7. Wire compensation: Performance, SPS MDs, pulsed system

    CERN Document Server

    Dorda, U

    2008-01-01

    A wire compensation (BBLR) scheme has been proposed in order to improve the long range beam-beam performance of the nominal LHC and its phase 1 and phase 2 upgrades[1]. In this paper we present experimental experience of the CERN SPS wires (BBLR) and report on progress with the RF BBLR.

  8. 75 FR 4584 - Wire Decking From China

    Science.gov (United States)

    2010-01-28

    ... and whether shipped as a kit or packaged separately. Wire decking is produced from carbon or alloy..., zinc or nickel coated), coated (e.g., with paint, epoxy, or plastic), or uncoated (``raw''). The wire... before June 28, 2010, but such final comments must not contain new factual information and must otherwise...

  9. MRI compatibility study of an integrated PET/RF-coil prototype system at 3T.

    Science.gov (United States)

    Akram, Md Shahadat Hossain; Obata, Takayuki; Suga, Mikio; Nishikido, Fumihiko; Yoshida, Eiji; Saito, Kazuyuki; Yamaya, Taiga

    2017-10-01

    We have been working on the development of a PET insert for existing magnetic resonance imaging (MRI) systems for simultaneous PET/MR imaging, which integrates radiofrequency (RF)-shielded PET detector modules with an RF head coil. In order to avoid interferences between the PET detector circuits and the different MRI-generated electromagnetic fields, PET detector circuits were installed inside eight Cu-shielded fiber-reinforced plastic boxes, and these eight shielded PET modules were integrated in between the eight elements of a 270-mm-diameter and 280-mm-axial-length cylindrical birdcage RF coil, which was designed to be used with a 3-T clinical MRI system. The diameter of the PET scintillators with a 12-mm axial field-of-view became 255mm, which was very close to the imaging region. In this study, we have investigated the effects of this PET/RF-coil integrated system on the performance of MRI, which include the evaluation of static field (Bo) inhomogeneity, RF field (B1) distribution, local specific absorption rate (SAR) distribution, average SAR, and signal-to-noise ratio (SNR). For the central 170-mm-diameter and 80-mm-axial-length of a homogenous cylindrical phantom (with the total diameter of 200mm and axial-length of 100mm), an increase of about a maximum of 3μT in the Bo inhomogeneity was found, both in the central and 40-mm off-centered transverse planes, and a 5 percentage point increase of B1 field inhomogeneity was observed in the central transverse plane (from 84% without PET to 79% with PET), while B1 homogeneity along the coronal plane was almost unchanged (77%) following the integration of PET with the RF head coil. The average SAR and maximum local SAR were increased by 1.21 and 1.62 times, respectively. However, the SNR study for both spin-echo and gradient-echo sequences showed a reduction of about 70% and 60%, respectively, because of the shielded PET modules. The overall results prove the feasibility of this integrated PET/RF-coil system for

  10. Wire scanners in low energy accelerators

    CERN Document Server

    Elmfors, P; Huhtinen, M; Lindroos, M; Olsfors, J; Raich, U

    1997-01-01

    Fast wire scanners are today considered as part of standard instrumentation in high energy synchrotrons. The extension of their use to synchrotrons working at lower energies, where Coulomb scattering can be important and the transverse beam size is large, introduces new complications considering beam heating of the wire, composition of the secondary particle shower and geometrical consideration in the detection set-up. A major problem in treating these effects is that the creation of secondaries in a thin carbon wire by a energetic primary beam is difficult to describe in an analytical way. We are here presenting new results from a full Monte Carlo simulation of this process yielding information on heat deposited in the wire, particle type and energy spectrum of secondaries and angular dependence as a function of primary beam energy. The results are used to derive limits for the use of wire scanners in low energy accelerators.

  11. Biocide-mediated corrosion of coiled tubing.

    Science.gov (United States)

    Sharma, Mohita; An, Dongshan; Liu, Tao; Pinnock, Tijan; Cheng, Frank; Voordouw, Gerrit

    2017-01-01

    Coiled tubing corrosion was investigated for 16 field water samples (S5 to S20) from a Canadian shale gas field. Weight loss corrosion rates of carbon steel beads incubated with these field water samples averaged 0.2 mm/yr, but injection water sample S19 had 1.25±0.07 mm/yr. S19 had a most probable number of zero acid-producing bacteria and incubation of S19 with carbon steel beads or coupons did not lead to big changes in microbial community composition. In contrast other field water samples had most probable numbers of APB of 102/mL to 107/mL and incubation of these field water samples with carbon steel beads or coupons often gave large changes in microbial community composition. HPLC analysis indicated that all field water samples had elevated concentrations of bromide (average 1.6 mM), which may be derived from bronopol, which was used as a biocide. S19 had the highest bromide concentration (4.2 mM) and was the only water sample with a high concentration of active bronopol (13.8 mM, 2760 ppm). Corrosion rates increased linearly with bronopol concentration, as determined by weight loss of carbon steel beads, for experiments with S19, with filtered S19 and with bronopol dissolved in defined medium. This indicated that the high corrosion rate found for S19 was due to its high bronopol concentration. The corrosion rate of coiled tubing coupons also increased linearly with bronopol concentration as determined by electrochemical methods. Profilometry measurements also showed formation of multiple pits on the surface of coiled tubing coupon with an average pit depth of 60 μm after 1 week of incubation with 1 mM bronopol. At the recommended dosage of 100 ppm the corrosiveness of bronopol towards carbon steel beads was modest (0.011 mm/yr). Higher concentrations, resulting if biocide is added repeatedly as commonly done in shale gas operations, are more corrosive and should be avoided. Overdosing may be avoided by assaying the presence of residual biocide by HPLC

  12. Validation of welding technology for ITER TF coil structures

    Energy Technology Data Exchange (ETDEWEB)

    Chida, Yutaka, E-mail: chida.yutaka@jaea.go.jp [Japan Atomic Energy Agency (Japan); Iguchi, Masahide; Takano, Katutoshi; Nakajima, Hideo [Japan Atomic Energy Agency (Japan); Oosemochi, Koichi [Toshiba Corporation (Japan); Niimi, Kenichiro; Tokai, Daisuke [Kawasaki Heavy Industries, LTD. (Japan); Gallix, Remy [ITER Organization (France)

    2011-12-15

    Japan Atomic Energy Agency (JAEA), acting as the Japan Domestic Agency (JADA) in the ITER project is responsible for the procurement of 9 Toroidal Field (TF) coil winding packs (WPs), structures for 19 TF coils (including one spare), and assembly of the WPs and the coil structures for 9 TF coils . The TF Coil structures which support large electromagnetic force generated in TF coils under the cryogenic temperature (about 4 K), are very large welded structures composed of a coil case and structural attachments made of high strength and high toughness stainless steel. JAEA has been performing welding trials for heavy thickness materials since 2008 and is planning fabrication of full-scale mock-ups of main sub-components (1 set for the inboard side and 1 set for the outboard side) in 2011 in order to investigate the technical issues for manufacturing the TF coil structures. This paper presents the results of welding trials and the status of full scale mock-ups fabrication to confirm the validity of welding technology and manufacturing design before fabricating the actual products.

  13. First assembly phase for the ATLAS toroid coils

    CERN Multimedia

    Patrice Loïez

    2003-01-01

    The ATLAS barrel toroid system consists of eight coils, each of axial length 25.3 m, assembled radially and symmetrically around the beam axis. The coils are of a flat racetrack type with two double-pancake windings made of 20.5 kA aluminium-stabilized niobium-titanium superconductor. In the first phase of assembly, the two 'pancakes' are packed into their vacuum vessel. This is done using bladders filled with resin and glass microbeads under pressure. The resin is heated and, once cooled, holds the pancakes in place. The operation has to be performed on both sides of the coil, which necessitated a special technique to turn the coils over and then transport them to the heating table. Photos 01, 02, 03: Use of the overhead travelling crane to hoist the coil up and then tilt it over, the coil frame's metal feet being used as rotational pivots, supporting half the coil's weight. Once it has been turned over, the coil, now with only half the frame, is transported to the heating table using a special lifting gant...

  14. Device for measuring elastic modulus of superconducting coils (See 7903169)

    CERN Multimedia

    1979-01-01

    This device was made to measure elastic modulus of the Po dipole superconducting coils. More elaborated devices, but based on the same concept, were later used to measure the apparent elastic moduli of the LHC superconducting magnet coils. See also 7903169, 7901386.

  15. Second Barrel Toroid Coil Installed in ATLAS Cavern

    CERN Multimedia

    Tappern, G.

    The second barrel toroid coil was lowered into the ATLAS Cavern on Friday, 26 November. The operation takes approximately five hours of precision crane and winch operations. Before lowering, several checks are made to ensure that no loose items have been left on the coil which would fall during the lowering down the shaft. This is a very difficult, but very important check, with the first coil in position, and partly below the shaft. After changing the winch tooling on Wednesday December 1st, the coil was lifted, rotated and placed into the feet. The girders which support the coil and the Z direction stops had all been pre-set before putting the coil in the feet. The angle is controlled by an inclinometer. When the final adjustments of position have been made, which will locate the coils at the plus/minus two mm level, the connection beams (voussoirs and struts) will be put in place; this requires a complex shimming procedure. This will lock together the two coils into the feet and forms the foundation for th...

  16. Dependence on winding tensions for stability of a superconducting coil

    Science.gov (United States)

    Takeo, Masakatsu; Sato, Seiki; Matsuo, Masaaki; Kiss, Takanobu; Takao, Tomoaki; Yamanaka, Atsuhiko; Kashima, Toshihiro; Mito, Toshiyuki; Minamizato, Kazushige

    2003-10-01

    The purpose of this study is to manufacture a high performance superconducting pulse coil by using high strength polyethylene fiber (DF; Dyneema ® fiber) reinforced plastic (DFRP) or Dyneema-glass hybrid composite fiber reinforced plastic (DGFRP) as material of a coil bobbin, which has negative thermal expansion, low frictional coefficient and high thermal conductivity. Description in this paper is as follows. First, thermal strains of several kinds of FRP pipes made by filament-winding (FW) method are measured, and the measured results well agreed with calculated ones by our proposed calculation method about thermal strains of a FW-pipe form. This shows that thermal expansion can be controlled by the proposed design technique of a DGFRP FW-pipe. Moreover, frictional coefficients of FRP plates using as coil structural material are measured and frictional heats are calculated for respective material when contact forces are changed. From these results, we find that the lower winding tension of a coil generates the smaller frictional heat when the frictional coefficient of the coil structural material is low. Furthermore, we systematically measure quench characteristics of many specimens of small superconducting coils using DFRP or DGFRP bobbins with different thermal expansions. From the results of quench tests, we find that the higher winding tension's coils tend to decrease quench current when the coil's bobbin expanded to a direction of circumference during the cooling down to cryogenic temperature, and suitable values of winding tension in a coil are located in region of 2-4 kg/mm 2. Finally, we design and manufacture 100 kJ class superconducting pulse coil by using a DGFRP bobbin, which wound in winding tension of 4 kg/mm 2. In addition, we prepare another 100 kJ class coil with the higher winding tensions of 8 kg/mm 2, and the quench characteristics of the coils are compared. The quench currents in the coils exceed the 95% rating on the load line for critical

  17. Power Consumption and BER of Flip-Flop Inserted Global Interconnect

    Directory of Open Access Journals (Sweden)

    Jingye Xu

    2007-01-01

    Full Text Available In nanometer scale integrated circuits, concurrent insertion of repeaters and sequential elements into the global interconnect lines has been proposed to support multicycle communication—a concept known as interconnect pipelining. The design targets of an interconnect-pipelining scheme are to ensure high reliability, low-power consumption, and less delay cycles. This paper presents an in-depth analysis of the reliability in terms of bit error rate (BER and the power consumption of wire-pipelining scheme. In this analysis, the dependencies of power consumption and BER on the number of inserted flip-flops, and the size of repeaters are illustrated. To trade off the design targets (wire delay, BER, and power consumption, a methodology is developed to optimize the repeater size and the number of flip-flops inserted which maximize a user-specified figure of merit. The methodology is demonstrated by calculating optimal solutions for interconnect pipelining for some International Technology Roadmap for Semiconductor technology nodes.

  18. Modified Rogowski coil for the detection of fast plane currents

    Science.gov (United States)

    Nassisi, V.; Delle Side, D.

    2017-09-01

    Rogowski coils are used to diagnostic currents of cylindrical configuration, therefore they are known to have a toroidal geometry. Nowadays, also linear transmission lines can be developed to get planar beams. Therefore, linear Rogowski coil to detect current pulses inside the linear conductors are necessary. For large devices, the theory necessary to study the system is that of the transmission lines, especially if the pulse width is comparable to the propagating time of signal inside the detector. The device we developed is able to record pulses more than 80 ns long with rise time near 500 ps. The former depends on the inductance value, load impedance and resistance of the coil; while the second on the mechanical configuration of coil loops. Theoretically, the attenuation coefficient depends exclusively on the turn number of the coil, while experimentally it is found to depend also on the current distribution inside the line.

  19. Random coil chemical shift for intrinsically disordered proteins

    DEFF Research Database (Denmark)

    Kjærgaard, Magnus; Brander, Søren; Poulsen, Flemming Martin

    2011-01-01

    Secondary chemical shift analysis is the main NMR method for detection of transiently formed secondary structure in intrinsically disordered proteins. The quality of the secondary chemical shifts is dependent on an appropriate choice of random coil chemical shifts. We report random coil chemical....... Temperature has a non-negligible effect on the (13)C random coil chemical shifts, so temperature coefficients are reported for the random coil chemical shifts to allow extrapolation to other temperatures. The pH dependence of the histidine random coil chemical shifts is investigated in a titration series...... shifts and sequence correction factors determined for a GGXGG peptide series following the approach of Schwarzinger et al. (J Am Chem Soc 123(13):2970-2978, 2001). The chemical shifts are determined at neutral pH in order to match the conditions of most studies of intrinsically disordered proteins...

  20. Differential Search Coils Based Magnetometers: Conditioning, Magnetic Sensitivity, Spatial Resolution

    Directory of Open Access Journals (Sweden)

    Timofeeva Maria

    2012-03-01

    Full Text Available A theoretical and experimental comparison of optimized search coils based magnetometers, operating either in the Flux mode or in the classical Lenz-Faraday mode, is presented. The improvements provided by the Flux mode in terms of bandwidth and measuring range of the sensor are detailed. Theory, SPICE model and measurements are in good agreement. The spatial resolution of the sensor is studied which is an important parameter for applications in non destructive evaluation. A general expression of the magnetic sensitivity of search coils sensors is derived. Solutions are proposed to design magnetometers with reduced weight and volume without degrading the magnetic sensitivity. An original differential search coil based magnetometer, made of coupled coils, operating in flux mode and connected to a differential transimpedance amplifier is proposed. It is shown that this structure is better in terms of volume occupancy than magnetometers using two separated coils without any degradation in magnetic sensitivity. Experimental results are in good agreement with calculations.

  1. Electromagnetic Design of Superconducting Dipoles Based on Sector Coils

    CERN Document Server

    Todesco, Ezio

    2007-01-01

    We study the coil lay-outs of superconducting dipoles for particle accelerators based on the sector geometry. We show that a simple model based on a sector coil with a wedge allows us to derive an equation giving the short sample field as a function of the aperture, coil width, cable properties and superconducting material. The equation agrees well with the actual results of several dipole coils that have been built in the last 30 years. The improvements due to the grading technique and the iron yoke are also studied. The proposed equation can be used as a benchmark to judge the efficiency of the coil design, and to carry out a global optimization of an accelerator lay-out.

  2. First assembly phase for the ATLAS toroid coils

    CERN Multimedia

    Maximilien Brice

    2003-01-01

    The ATLAS barrel toroid system consists of eight coils, each of axial length 25.3 m, assembled radially and symmetrically around the beam axis. The coils are of a flat racetrack type with two double-pancake windings made of 20.5 kA aluminium-stabilized niobium-titanium superconductor. In the first phase of assembly, the two 'pancakes' are packed into their vacuum vessel. This is done using bladders filled with resin and glass microbeads under pressure. The resin is heated and, once cooled, holds the pancakes in place. The operation has to be performed on both sides of the coil, which necessitated a special technique to turn the coils over and then transport them to the heating table. Photos 01, 02, 03: Transporting the coil to the heating table using a special lifting gantry manufactured at JINR-Dubna, Russia in preparation for the 'bladderisation' operation.

  3. Transformer current sensor for superconducting magnetic coils

    Science.gov (United States)

    Shen, Stewart S.; Wilson, C. Thomas

    1988-01-01

    A transformer current sensor having primary turns carrying a primary current for a superconducting coil and secondary turns only partially arranged within the primary turns. The secondary turns include an active winding disposed within the primary turns and a dummy winding which is not disposed in the primary turns and so does not experience a magnetic field due to a flow of current in the primary turns. The active and dummy windings are wound in opposite directions or connected in series-bucking relationship, and are exposed to the same ambient magnetic field. Voltages which might otherwise develop in the active and dummy windings due to ambient magnetic fields thus cancel out. The resultant voltage is purely indicative of the rate of change of current flowing in the primary turns.

  4. Design and construction of a novel 1H/19F double-tuned coil system using PIN-diode switches at 9.4T.

    Science.gov (United States)

    Choi, Chang-Hoon; Hong, Suk-Min; Ha, YongHyun; Shah, N Jon

    2017-06-01

    A double-tuned 1H/19F coil using PIN-diode switches was developed and its performance evaluated. The is a key difference from the previous developments being that this design used a PIN-diode switch in series with an additionally inserted inductor in parallel to one of the capacitors on the loop. The probe was adjusted to 19F when the reverse bias voltage was applied (PIN-diode OFF), whilst it was switched to 1H when forward current was flowing (PIN-diode ON). S-parameters and Q-factors of single- and double-tuned coils were examined and compared with/without a phantom on the bench. Imaging experiments were carried out on a 9.4T preclinical scanner. All coils were tuned at resonance frequencies and matched well. It is shown that the Q-ratio and SNR of double-tuned coil at 19F frequency are nearly as good as those of a single-tuned coil. Since the operating frequency was tuned to 19F when the PIN-diodes were turned off, losses due to PIN-diodes were substantially lower resulting in the provision of excellent image quality of X-nuclei. Copyright © 2017 Elsevier Inc. All rights reserved.

  5. Sequential cooling insert for turbine stator vane

    Energy Technology Data Exchange (ETDEWEB)

    Jones, Russel B

    2017-04-04

    A sequential flow cooling insert for a turbine stator vane of a small gas turbine engine, where the impingement cooling insert is formed as a single piece from a metal additive manufacturing process such as 3D metal printing, and where the insert includes a plurality of rows of radial extending impingement cooling air holes alternating with rows of radial extending return air holes on a pressure side wall, and where the insert includes a plurality of rows of chordwise extending second impingement cooling air holes on a suction side wall. The insert includes alternating rows of radial extending cooling air supply channels and return air channels that form a series of impingement cooling on the pressure side followed by the suction side of the insert.

  6. Antibody engineering using phage display with a coiled-coil heterodimeric Fv antibody fragment.

    Directory of Open Access Journals (Sweden)

    Xinwei Wang

    Full Text Available A Fab-like antibody binding unit, ccFv, in which a pair of heterodimeric coiled-coil domains was fused to V(H and V(L for Fv stabilization, was constructed for an anti-VEGF antibody. The anti-VEGF ccFv showed the same binding affinity as scFv but significantly improved stability and phage display level. Furthermore, phage display libraries in the ccFv format were constructed for humanization and affinity maturation of the anti-VEGF antibody. A panel of V(H frameworks and V(H-CDR3 variants, with a significant improvement in affinity and expressibility in both E. coli and yeast systems, was isolated from the ccFv phage libraries. These results demonstrate the potential application of the ccFv antibody format in antibody engineering.

  7. An improvement of airflow and heat transfer performance of multi-coil condensers by different coil configurations

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Tzong-Shing; Wu, Wu-Chieh; Chuah, Yew-Khoy; Wang, Sheng-Kai [Department of Energy and Refrigerating Air-Conditioning Engineering, National Taipei University of Technology, 1, Sec.3, Chung-Hsiao E. Rd., Taipei 106 (China)

    2010-11-15

    Mal-distribution of airflow is an important factor for the performance of air-cooled multi-coil air-cooled condensers. This study is an attempt to investigate the effects of different included angles between the coils of the condenser. It has been found in this study that it can be a mean to improve the performance of multi-coil condensers without using larger heat transfer surfaces. A commercially used four-coil condenser of an air-cooled water chiller was used as the base case in the tests and analysis. The results show that the variation of the included angle can increase the airflow rate by 7.85%, which corresponds to 5.29% increase in heat transfer. The improvements were found to be due to the reduction of the stagnant flow regions of the heat exchanger coils, and more even flow distribution through the coils. Test data were used to verify the computer model of the four-coil heat exchanger. The same tested fan performance characteristic was used in all of the analyses. The research results are important as air-cooled condensing units can be designed to better performance merely by changing the configuration of the coil arrangements. (author)

  8. Analysis and experimental study of wireless power transfer with HTS coil and copper coil as the intermediate resonators system

    Science.gov (United States)

    Wang, Xiufang; Nie, Xinyi; Liang, Yilang; Lu, Falong; Yan, Zhongming; Wang, Yu

    2017-01-01

    Intermediate resonator (repeater) between transmitter and receiver can significantly increase the distance of wireless power transfer (WPT) and the efficiency of wireless power transfer. The wireless power transfer via strongly coupled magnetic resonances with an high temperature superconducting (HTS) coil and copper coil as intermediate resonators was presented in this paper. The electromagnetic experiment system under different conditions with different repeating coils were simulated by finite element software. The spatial distribution patterns of magnetic induction intensity at different distances were plotted. In this paper, we examined transfer characteristics with HTS repeating coil and copper repeating coil at 77 K and 300 K, respectively. Simulation and experimental results show that HTS and copper repeating coil can effectively enhance the space magnetic induction intensity, which has significant effect on improving the transmission efficiency and lengthening transmission distance. We found that the efficiency and the distance of wireless power transfer system with an HTS coil as repeater is much higher by using of copper coil as repeater.

  9. Self-assembly of designed coiled coil peptides studied by small-angle X-ray scattering and analytical ultracentrifugation

    DEFF Research Database (Denmark)

    Malik, Leila; Nygaard, Jesper; Christensen, Niels Johan

    2013-01-01

    , they are promising tools for the construction of nanomaterials. Small-angle X-ray scattering (SAXS) has emerged as a new biophysical technique for elucidation of protein topology. Here, we describe a systematic study of the self-assembly of a small ensemble of coiled coil sequences using SAXS and analytical...

  10. Magnetization Dynamics of Amorphous Ribbons and Wires Studied by Inductance Spectroscopy

    Directory of Open Access Journals (Sweden)

    Israel Betancourt

    2010-12-01

    Full Text Available Inductance spectroscopy is a particular formulation variant of the well known complex impedance formalism typically used for the electric characterization of dielectric, ferroelectric, and piezoelectric materials. It has been successfully exploited as a versatile tool for characterization of the magnetization dynamics in amorphous ribbons and wires by means of simple experiments involving coils for sample holding and impedance analyzer equipment. This technique affords the resolution of the magnetization processes in soft magnetic materials, in terms of reversible deformation of pinned domain walls, domain wall displacements and spin rotation, for which characteristic parameters such as the alloy initial permeability and the relaxation frequencies, indicating the dispersion of each process, can be defined. Additionally, these parameters can be correlated with chemical composition variation, size effects and induced anisotropies, leading to a more physical insight for the understanding of the frequency dependent magnetic response of amorphous alloys, which is of prime interest for the development of novel applications in the field of telecommunication and sensing technologies. In this work, a brief overview, together with recent progress on the magnetization dynamics of amorphous ribbons, wires, microwires and biphase wires, is presented and discussed for the intermediate frequency interval between 10 Hz and 13 MHz.

  11. Magnetization Dynamics of Amorphous Ribbons and Wires Studied by Inductance Spectroscopy.

    Science.gov (United States)

    Betancourt, Israel

    2010-12-23

    Inductance spectroscopy is a particular formulation variant of the well known complex impedance formalism typically used for the electric characterization of dielectric, ferroelectric, and piezoelectric materials. It has been successfully exploited as a versatile tool for characterization of the magnetization dynamics in amorphous ribbons and wires by means of simple experiments involving coils for sample holding and impedance analyzer equipment. This technique affords the resolution of the magnetization processes in soft magnetic materials, in terms of reversible deformation of pinned domain walls, domain wall displacements and spin rotation, for which characteristic parameters such as the alloy initial permeability and the relaxation frequencies, indicating the dispersion of each process, can be defined. Additionally, these parameters can be correlated with chemical composition variation, size effects and induced anisotropies, leading to a more physical insight for the understanding of the frequency dependent magnetic response of amorphous alloys, which is of prime interest for the development of novel applications in the field of telecommunication and sensing technologies. In this work, a brief overview, together with recent progress on the magnetization dynamics of amorphous ribbons, wires, microwires and biphase wires, is presented and discussed for the intermediate frequency interval between 10 Hz and 13 MHz.

  12. Wire pad chamber for LHCb muon system

    CERN Document Server

    Botchine, B; Lazarev, V A; Sagidova, N; Vorobev, A P; Vorobyov, A; Vorobyov, Alexei

    2000-01-01

    2000-003 Wire pad chambers (WPC) have been proposed for the outer Region 4 of the LHCb Muon System. These are double gap MWPCs with small wire spacing allowing to obtain 99% detection efficiency in a 20 ns time window. The chambers have a rectangular shape with the vertical dimension from 20 cm in Station 1 to 30 cm in Station 5. The horizontal dimensions will be different with the maximal size of 3 meters in Station 5. The wires are in the vertical direction. The short wire length allows to use small wire spacing needed for high time resolution. Also, this helps to obtain the uniform gas gain over the whole chamber area. The WPC has one row of the wire pads formed by grouping wires in separate readout channels. Four WPC prototypes have been built at PNPI and tested in the PS beam at CERN. Here we report on the results from these tests. Also, the results of simulation of the WPC performance are presented.

  13. Coil concepts for rapid and motion-compensated MR-Imaging of small animals; Spulenkonzepte zur schnellen und bewegungskompensierten MR-Bildgebung von Kleintieren

    Energy Technology Data Exchange (ETDEWEB)

    Korn, Matthias

    2009-05-06

    In this work radiofrequency-coils for the imaging of small animals in clinical whole-body MRI-systems were developed. Therefore in a first step single-channel solenoids were designed and characterized. The solenoids had two and three windings respectively, which were implemented as double wires to increase the homogeneity of the receive profile. These coils allow the acquisition of whole-body images of mice with high signal-to-noise ratio and homogeneity over a distance of at least 6.3 cm. Since many imaging experiments require rapid image acquisition, in the next step a novel coil concept was developed, which, due to its geometry, enables parallel imaging in arbitrary directions. A prototype was assembled and tested on phantom and small-animal experiments. With an accelerating factor of R=2, the difference of the SNR in all directions from the theoretical maximum, was less than 1%. In order to compensate physiological motion by the self-gating technique, in this work a coil is presented for the first time, which selectively amplifies the self-gating signal, while - due to a optical detuning technique - preserving the homogeneous illumination of the image. In vivo experiments on a small animal show an amplification of the self-gating signal by at least 40%. (orig.)

  14. In-Situ Wire Damage Detection System

    Science.gov (United States)

    Williams, Martha; Roberson, Luke; Tate, Lanetra; Smith, Trent; Gibson, Tracy; Medelius, Pedro; Jolley, Scott

    2012-01-01

    An In-Situ Wire Damage Detection System (ISWDDS) has been developed that is capable of detecting damage to a wire insulation, or a wire conductor, or to both. The system will allow for realtime, continuous monitoring of wiring health/integrity and reduce the number of false negatives and false positives while being smaller, lighter in weight, and more robust than current systems. The technology allows for improved safety and significant reduction in maintenance hours for aircraft, space vehicles, satellites, and other critical high-performance wiring systems for industries such as energy production and mining. The integrated ISWDDS is comprised of two main components: (1) a wire with an innermost core conductor, an inner insulation film, a conductive layer or inherently conductive polymer (ICP) covering the inner insulation film, an outermost insulation jacket; and (2) smart connectors and electronics capable of producing and detecting electronic signals, and a central processing unit (CPU) for data collection and analysis. The wire is constructed by applying the inner insulation films to the conductor, followed by the outer insulation jacket. The conductive layer or ICP is on the outer surface of the inner insulation film. One or more wires are connected to the CPU using the smart connectors, and up to 64 wires can be monitored in real-time. The ISWDDS uses time domain reflectometry for damage detection. A fast-risetime pulse is injected into either the core conductor or conductive layer and referenced against the other conductor, producing transmission line behavior. If either conductor is damaged, then the signal is reflected. By knowing the speed of propagation of the pulse, and the time it takes to reflect, one can calculate the distance to and location of the damage.

  15. Experimental setup to detect superconducting wire motion

    Science.gov (United States)

    Ruwali, K.; Yamanaka, A.; Teramoto, Y.; Nakanishi, K.; Hosoyama, K.

    2009-04-01

    An experimental setup was designed and fabricated to study superconducting wire motion under the influence of electromagnetic force. Experiments were conducted at 4.2 K by varying the experimental conditions such as the tension to the superconducting wire and different insulating materials at the interface of the superconducting wire and head part. The insulating materials used in the experiments were polyimide film and a high strength polyethylene fiber cloth, Dyneema. Details of the experimental setup and the test results are reported in this paper.

  16. Lasing from a single quantum wire

    OpenAIRE

    Hayamizu, Yuhei; Yoshita, Masahiro; Watanabe, Shinichi; Akiyama, Hidefumi; Pfeiffer, Loren N.; West, Ken W.

    2002-01-01

    A laser with an active volume consisting of only a single quantum wire in the 1-dimensional (1-D) ground state is demonstrated. The single wire is formed quantum-mechanically at the T-intersection of a 14 nm Al_{0.07}Ga_{0.93}As quantum well and a 6 nm GaAs quantum well, and is embedded in a 1-D single-mode optical waveguide. We observe single-mode lasing from the quantum wire ground state by optical pumping. The laser operates from 5 to 60 K, and has a low threshold pumping power of 5 mW at ...

  17. Experimental setup to detect superconducting wire motion

    Directory of Open Access Journals (Sweden)

    K. Ruwali

    2009-04-01

    Full Text Available An experimental setup was designed and fabricated to study superconducting wire motion under the influence of electromagnetic force. Experiments were conducted at 4.2 K by varying the experimental conditions such as the tension to the superconducting wire and different insulating materials at the interface of the superconducting wire and head part. The insulating materials used in the experiments were polyimide film and a high strength polyethylene fiber cloth, Dyneema. Details of the experimental setup and the test results are reported in this paper.

  18. External Iliac Artery-Appendicular Fistula due to Antegrade Unusual Migration of K-Wire from Hip to Pelvis: An Unreported Complication

    Directory of Open Access Journals (Sweden)

    Nagmani Singh

    2015-01-01

    Full Text Available Background. K-wires are thought to be extremely safe implants and complications as a result of direct insertion or migration are very rare. Complications may be life-threatening in some instances where migration results in injury to vital organs. We report one such case where antegrade migration of K-wire from the hip resulted in injury to external iliac artery and formation of external iliac artery-appendicular fistula. No such complication due to migration has ever been reported in the literature. Case Description. A 15-year-old boy presented with lower abdominal pain, right lower limb swelling and pain, inability to walk, and rectal bleeding for 1 month after 2 K-wires had been inserted in his right hip joint for treatment of slipped capital femoral epiphysis the previous year. On investigation, he was diagnosed to have external iliac artery-appendicular fistula for which he was surgically treated. Clinical Relevance. Antegrade migration of K-wire from hip joint may lead to life-threatening injuries which can be minimized by bending the end of the K-wire, keeping the tip protruding outside the skin wherever possible and by early removal of K-wire once its purpose has been achieved.

  19. Endothelial cell proliferation in swine experimental aneurysm after coil embolization.

    Directory of Open Access Journals (Sweden)

    Yumiko Mitome-Mishima

    Full Text Available After coil embolization, recanalization in cerebral aneurysms adversely influences long-term prognosis. Proliferation of endothelial cells on the coil surface may reduce the incidence of recanalization and further improve outcomes after coil embolization. We aimed to map the expression of proliferating tissue over the aneurysmal orifice and define the temporal profile of tissue growth in a swine experimental aneurysm model. We compared the outcomes after spontaneous thrombosis with those of coil embolization using histological and morphological techniques. In aneurysms that we not coiled, spontaneous thrombosis was observed, and weak, easily detachable proliferating tissue was evident in the aneurysmal neck. In contrast, in the coil embolization group, histological analysis showed endothelial-like cells lining the aneurysmal opening. Moreover, immunohistochemical and morphological analysis suggested that these cells were immature endothelial cells. Our results indicated the existence of endothelial cell proliferation 1 week after coil embolization and showed immature endothelial cells in septal tissue between the systemic circulation and the aneurysm. These findings suggest that endothelial cells are lead to and proliferate in the former aneurysmal orifice. This is the first examination to evaluate the temporal change of proliferating tissue in a swine experimental aneurysm model.

  20. Dynamics of entangled rod-coil block copolymers

    Science.gov (United States)

    Wang, Muzhou; Timachova, Ksenia; Alexander-Katz, Alfredo; Likhtman, Alexei E.; Olsen, Bradley D.

    2014-03-01

    Polymer science is exploring advanced materials which combine functional domains such as proteins and semiconducting polymers with traditional flexible polymers onto the same molecule. While many studies have focused on equilibrium structure-property relationships, little is known about how the conformational restrictions of rigid domains affect dynamical phenomena such as mechanical properties, processing pathways, and self-assembly kinetics. We have recently introduced a reptation theory for entangled rod-coil block copolymers as a model for this wider class of functional polymeric materials. The theory hypothesizes that the motion of rod-coils is slowed relative to rod and coil homopolymers because of a mismatch between the curvature of the rod and coil entanglement tubes. This effect leads to activated reptation and arm retraction as two relaxation mechanisms that govern the short and long rod regimes, respectively. These results were verified by tracer diffusion measurements using molecular dynamics simulation and forced Rayleigh scattering in both the rod-coil diblock and coil-rod-coil triblock configurations. The tracer diffusion results were then compared to experimental self-diffusion measurements which require a consideration of the motion of the surrounding chains.