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Sample records for winner melvin calvin

  1. Melvin Calvin: Fuels from Plants

    Energy Technology Data Exchange (ETDEWEB)

    Taylor, S.E.; Otvos, J.W.

    1998-11-24

    A logical extension of his early work on the path of carbon during photosynthesis, Calvin's studies on the production of hydrocarbons by plants introduced many in the scientific and agricultural worlds to the potential of renewable fuel and chemical feedstocks. He and his co-workers identified numerous candidate compounds from plants found in tropical and temperate climates from around the world. His travels and lectures concerning the development of alternative fuel supplies inspired laboratories worldwide to take up the investigation of plant-derived energy sources as an alternative to fossil fuels.

  2. Melvin Whitebooi

    African Journals Online (AJOL)

    Owner

    (1982), Dié kant dáái kant (1984), Koffie en kondensmelk (1986) en Die Goodbye People (1991). Dit sal die blêrrie dag wies!was Melvin (15 April 1956–10 November 2011) se debuut wat hy spesiaal vir die Cape Flats Players geskryf het en die gedwonge Distrik Ses- verskuiwings as tema gehad het. Dit het 'n aanduiding ...

  3. Calvin and mission

    Directory of Open Access Journals (Sweden)

    Jacobus (Kobus P. Labuschagne

    2009-11-01

    Full Text Available It has often been stated or implied that John Calvin and the Reformers in general were indifferent to or even against mission. The aim of this study is to point out that this understanding is not a true version of the facts. A thorough examination of the theology and actions of John Calvin, evaluated against the background of his times and world, reveals that he was firmly committed to spreading the Gospel of Jesus Christ, the Lord. Also the theological insights of Calvin and the Reformers not only provided the crucial theological basis to support the future massive missionary expansion of Protestant churches, but necessitate for all times Church mission as a sure consequence of their theology. Calvin’s theology can indeed be described as an ‘essentially missionary theology’. In the heart of Calvin’s theological thinking clearly features the doctrine of justifi cation – because medieval man’s concern for salvation needed to be answered.

  4. Calvin on Human Reason

    Directory of Open Access Journals (Sweden)

    Nicolaas Vorster

    2014-10-01

    Full Text Available In his recent book The Unintended Reformation, Brad Gregory makes the statement that the Reformation replaced the teleological social ethics of Roman Catholicism based on virtue with formal social ethics based on rules and enforced by magistrates, because they regarded human reason as too depraved to acquire virtue. The result, according to Gregory, is that the relation between internalised values and rules were undermined. This article asks whether this accusation is true with regard to Calvin. The first section discusses the intellectual environment of Calvin’s day – something that inevitably influenced his theory on reason, whilst the second part analyses Calvin’s view on the created nature of reason. The third section investigates Calvin’s view on the effects of sin on reason; and the fourth section discusses Calvin’s perspective on the relation between grace and reason. The article concludes that Gregory’s accusation against the Reformation is not applicable to Calvin. Gregory fails to take into account Calvin’s modified position that the imago Dei was not totally destroyed by sin as well as his teaching on common grace that maintains that even non-believers are able to acquire virtue through the common grace of God.

  5. Melvin Defleur's Information Communication Model: Its Application ...

    African Journals Online (AJOL)

    The paper discusses Melvin Defleur's information communication model and its application to archives administration. It provides relevant examples in which archives administration functions involve the communication process. Specific model elements and their application in archives administration are highlighted.

  6. Calvin dan Spiritualitas Kerahiman

    Directory of Open Access Journals (Sweden)

    Stella Yessy Exlentya Pattipeilohy

    2017-10-01

    Full Text Available The keyword commonly used in mysticism and spirituality is "experience". The instilling of God's mercy, in fact, is a spiritual experience accosted by God's love. Such experience is shared in a transformative praxis. The mercy of God is a faith experience that could be made a meeting point in fostering a love-based religious life. In the Protestant tradition, we can find a foothold for the development of spiritual theology on John Calvin's work, i.e. the so-called merciful spirituality. Today's experience of God's mercy is influenced by the contextual concern abaout the image of the Homeless Jesus. The refugees not only "challenge" Christian communities to recognise the Christ within the needy strangers, but also welcome them in love and peace despite religious faith differences.

  7. Calvin on Human Reason

    Directory of Open Access Journals (Sweden)

    Nicolaas Vorster

    2014-10-01

    Full Text Available In his recent book The Unintended Reformation, Brad Gregory makes the statement that the Reformation replaced the teleological social ethics of Roman Catholicism based on virtue with formal social ethics based on rules and enforced by magistrates, because they regarded human reason as too depraved to acquire virtue. The result, according to Gregory, is that the relation between internalised values and rules were undermined. This article asks whether this accusation is true with regard to Calvin. The first section discusses the intellectual environment of Calvin’s day – something that inevitably influenced his theory on reason, whilst the second part analyses Calvin’s view on the created nature of reason. The third section investigates Calvin’s view on the effects of sin on reason; and the fourth section discusses Calvin’s perspective on the relation between grace and reason. The article concludes that Gregory’s accusation against the Reformation is not applicable to Calvin. Gregory fails to take into account Calvin’s modified position that the imago Dei was not totally destroyed by sin as well as his teaching on common grace that maintains that even non-believers are able to acquire virtue through the common grace of God. Calvyn oor Menslike Rede. In sy onlangse boek, The Unintended Reformation, maak Brad Gregory die stelling dat die Reformasie die substantiewe teleologiese deugde-etiek van die Rooms-Katolisisme vervang het met ‘n formele etiek gebaseer op reëls wat deur magistrate afgedwing moet word. Die Reformasie was, volgens Gregory, van mening dat die menslike rede sodanig deur sonde geskend is dat die mens nie langer deugde kan beoefen nie. Dit het tot ‘n skadelike skeiding tussen waardes en reëls gelei. Hierdie artikel ondersoek die vraag of Gregory se stelling op Calvyn van toepassing is. Die eerste afdeling bespreek die intellektuele omgewing waarin Calvyn gewerk het. Tweedens word Gregory se siening van die geskape

  8. Evolutionary History of the Enzymes Involved in the Calvin-Benson Cycle in Euglenids.

    Science.gov (United States)

    Markunas, Chelsea M; Triemer, Richard E

    2016-05-01

    Euglenids are an ancient lineage that may have existed as early as 2 billion years ago. A mere 65 years ago, Melvin Calvin and Andrew A. Benson performed experiments on Euglena gracilis and elucidated the series of reactions by which carbon was fixed and reduced during photosynthesis. However, the evolutionary history of this pathway (Calvin-Benson cycle) in euglenids was more complex than Calvin and Benson could have imagined. The chloroplast present today in euglenophytes arose from a secondary endosymbiosis between a phagotrophic euglenid and a prasinophyte green alga. A long period of evolutionary time existed before this secondary endosymbiotic event took place, which allowed for other endosymbiotic events or gene transfers to occur prior to the establishment of the green chloroplast. This research revealed the evolutionary history of the major enzymes of the Calvin-Benson cycle throughout the euglenid lineage and showed that the majority of genes for Calvin-Benson cycle enzymes shared an ancestry with red algae and/or chromophytes suggesting they may have been transferred to the nucleus prior to the acquisition of the green chloroplast. © 2015 The Author(s) Journal of Eukaryotic Microbiology © 2015 International Society of Protistologists.

  9. Orientifolds of string theory Melvin backgrounds

    Energy Technology Data Exchange (ETDEWEB)

    Angelantonj, Carlo E-mail: carlo.angelantonj@cern.ch; Dudas, Emilian; Mourad, Jihad

    2002-08-19

    We study the dynamics of type I strings on Melvin backgrounds, with a single or multiple twisted two-planes. We construct two inequivalent types of orientifold models that correspond to (non-compact) irrational versions of Scherk-Schwarz type breaking of supersymmetry. In the first class of vacua, D-branes and O-planes are no longer localized in space-time but are smeared along the compact Melvin coordinate with a characteristic profile. On the other hand, the second class of orientifolds involves O-planes and D-branes that are both rotated by an angle proportional to the twist. In case of 'multiple Melvin spaces', some amount of supersymmetry is recovered if the planes are twisted appropriately and part of the original O-planes are transmuted into new ones. The corresponding boundary and crosscap states are determined.

  10. Calvin on church and government

    Directory of Open Access Journals (Sweden)

    W.A. Dreyer

    2010-07-01

    Full Text Available This article examines Calvin’s understanding of civil govern- ment as well as the relationship between church and govern- ment against the background of radical political change during the sixteenth century. It becomes clear that Calvin had an organic understanding of church, government and people. These three entities are interwoven and interact on the basis of the covenant and civil contract. Calvin’s approach, however, is not limited to the covenant, but has a surprising richness and diversity. He integrated theological, juristic and philosophical concepts in his understanding of the state. It is further shown that Calvin’s high regard for civil government, entrenched the corpus christianum, even though he clearly distinguished between ecclesiastical and civil governance. It is also shown that Calvin had a fundamental influence on many of the political concepts which are generally accepted within modern democra- cies.

  11. John Calvin and the Belgic Confession

    Directory of Open Access Journals (Sweden)

    S. A. Strauss

    1993-06-01

    Full Text Available Calvin's influence on the Belgic Confession is usually taken for granted. In this article this traditional view' is subjected to a critical study. Firstly a historical investigation is made of the possible biographic contact that John Calvin (1509-64 and Guido de Brés (1522-67 could have had. This investigation lead's to the conclusion that the latter was a close pupil of the former Calvin exercised influence on the Belgic Confession (1561 via the Confessio Gailicana (1559. When comparing the general theological con­tent of the Belgic Confession with the Institutes of Calvin, significant simi­larities are found.

  12. Calvin and mission | Labuschagne | HTS Teologiese Studies ...

    African Journals Online (AJOL)

    It has often been stated or implied that John Calvin and the Reformers in general were indifferent to or even against mission. The aim of this study is to point out that this understanding is not a true version of the facts. A thorough examination of the theology and actions of John Calvin, evaluated against the background of his ...

  13. Calvins Sozialethik und der Kapitalismus

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    H. H. Eßer

    1992-01-01

    Full Text Available Calvin’s social ethics and the origin of modem Capitalism This paper starts off by introducing the prejudices against the mentioned theme and its continuing effects, and stresses in the conclusion that the so-called Max Weber thesis was corrected by Weber himself. He explained its validity more in terms of seventeenth-century Puritanism than for its direct connection to the social doctrine of Calvin. The second heading reports the discussion and refutation of the Max Weber thesis in sociological, historical and theological literature. Calvin’s work on social-ethics is also honoured. The concluding ten theses sum up the importance of Calvin’s fundamental social-ethics for the solution of Geneva’s economic problems.

  14. John Calvin and postmodern spirituality

    Directory of Open Access Journals (Sweden)

    P.H. Fick

    2010-07-01

    Full Text Available Postmodernists reject universal truth claims and brand them as violent impositions on a person by powerful institutions. Postmodernist spirituality seeks for a more subjective, life- experience based attitude towards values and truths of the Bible and relationship in community. Careful consideration should be given to the issues of community, knowledge/truth, faith, and faith experience. This article will show that, in his “Institutes”, Calvin gives ample attention to faith, the liberating truth about God as revealed in Jesus Christ, and to the Chris- tian’s intimate relationship with Him. Being in Christ, commu- nion with Christ or the “unio mystica cum Christo” through faith as a central theme in Calvin’s theology, needs to be redis- covered and re-applied to reformed spirituality as apologetic means in a postmodern world. This treasure should satisfy the kind of spirituality postmodernists yearn for.

  15. An investigation into Calvin's use of Augustine | Han | Acta Theologica

    African Journals Online (AJOL)

    This article briefly investigates the use of Augustine as an authority from the early church in John Calvin's writings. Calvin frequently referred to and quoted Augustine in his writings. Augustine undoubtedly exerted an influence on Calvin's views and arguments. This article traces Calvin's use of Augustine in his writings ...

  16. Microscopic thin-shell wormholes in magnetic Melvin universe

    Energy Technology Data Exchange (ETDEWEB)

    Mazharimousavi, S.H.; Halilsoy, M.; Amirabi, Z. [Eastern Mediterranean University, Department of Physics, North Cyprus, Mersin 10 (Turkey)

    2014-05-15

    We construct thin-shell wormholes in the magnetic Melvin universe. It is shown that in order to make a TSW in the Melvin spacetime the radius of the throat cannot be larger than (2)/(B{sub 0}), in which B{sub 0} is the magnetic field constant. We also analyze the stability of the constructed wormhole in terms of a linear perturbation around the equilibrium point. In our stability analysis we scan a full set of the Equation of States such as Linear Gas, Chaplygin Gas, Generalized Chaplygin Gas, Modified Generalized Chaplygin Gas, and Logarithmic Gas. Finally we extend our study to the wormhole solution in the unified Melvin and Bertotti-Robinson spacetime. In this extension we show that for some specific cases, the local energy density is partially positive but the total energy which supports the wormhole is positive. (orig.)

  17. Photowalk contest winners

    CERN Multimedia

    Roberto Cantoni

    2010-01-01

    The local winners of the global particle physics Photowalk have been announced by the five participating laboratories. At CERN, Diego Giol and Christian Stephani were the jury’s favourites, and their photos will now go forward to the global vote, competing against the local winners from DESY in Germany, Fermilab in the US, KEK in Japan and TRIUMF in Canada. Two prizes are to be awarded, one selected by a global jury, the other by popular vote – it’s time to get voting!   Diego Giol #1 The global winners of the Photowalk contest will be revealed by the second week of October, but the local CERN winners were announced last week. After three weeks of work, two meetings of the jury and three successive selections, 20 photos were chosen from the 792 entries. The three highest-ranked will participate in the final competition. The public can vote for their favourite photos on the interactions.org website until 8 October. Only two photographers took the three winning photo...

  18. Calvin-Rehoboth Robotic Twin Telescopes

    Science.gov (United States)

    Haarsma, D. B.; Molnar, L. A.; VanBaak, D. A.

    2004-12-01

    The astronomy program at Calvin College, like many small colleges, is limited by poor weather and light pollution at its midwestern campus and by limited free time on the part of its astronomy faculty. Nonetheless we believe direct access to the physical universe is key to the science education both of science majors and nonmajors. Recent advances in hardware and software for modest robotic telescopes have made it possible for colleges like ours to incorporate the use of a remote bservatory into our curriculum within typical financial and time constraints. In this poster we make our first report on the installation of two robotic telescopes (one on campus and one at a remote site in New Mexico) using largely off-the-shelf components. Students learn first with the local telescope in order to understand the equipment and procedures, but obtain the majority of their data with the remote telescope. Equipment development is done first with the local telescope, and then implemented on the remote telescope (where time spent in development is difficult). We received an NSF CCLI grant and matching college funds in the summer of 2002. The local telescope was installed in the spring of 2003, and the New Mexico telescope was ready for remote operation in January 2004. Our poster will describe our equipment choices, including a few components (such as an equipment rack for the back end of the telescope) which we designed ourselves. It will also detail classroom use of the equipment in its first two semesters by students at a range of levels. A copy of the poster and many additional details of the project are available on the Calvin observatory website, http://www.calvin.edu/observatory/.

  19. Modeling the Calvin-Benson cycle

    Directory of Open Access Journals (Sweden)

    Jablonsky Jiri

    2011-11-01

    Full Text Available Abstract Background Modeling the Calvin-Benson cycle has a history in the field of theoretical biology. Anyone who intends to model this system will look at existing models to adapt, refine and improve them. With the goal to study the regulation of carbon metabolism, we investigated a broad range of relevant models for their suitability to provide the basis for further modeling efforts. Beyond a critical analysis of existing models, we furthermore investigated the question how adjacent metabolic pathways, for instance photorespiration, can be integrated in such models. Results Our analysis reveals serious problems with a range of models that are publicly available and widely used. The problems include the irreproducibility of the published results or significant differences between the equations in the published description of the model and model itself in the supplementary material. In addition to and based on the discussion of existing models, we furthermore analyzed approaches in PGA sink implementation and confirmed a weak relationship between the level of its regulation and efficiency of PGA export, in contrast to significant changes in the content of metabolic pool within the Calvin-Benson cycle. Conclusions In our study we show that the existing models that have been investigated are not suitable for reuse without substantial modifications. We furthermore show that the minor adjacent pathways of the carbon metabolism, neglected in all kinetic models of Calvin-Benson cycle, cannot be substituted without consequences in the mass production dynamics. We further show that photorespiration or at least its first step (O2 fixation has to be implemented in the model if this model is aimed for analyses out of the steady state.

  20. Discovery of causal mechanisms: Oxidative phosphorylation and the Calvin-Benson cycle.

    Science.gov (United States)

    Scholl, Raphael; Nickelsen, Kärin

    2015-06-01

    We investigate the context of discovery of two significant achievements of twentieth century biochemistry: the chemiosmotic mechanism of oxidative phosphorylation (proposed in 1961 by Peter Mitchell) and the dark reaction of photosynthesis (elucidated from 1946 to 1954 by Melvin Calvin and Andrew A. Benson). The pursuit of these problems involved discovery strategies such as the transfer, recombination and reversal of previous causal and mechanistic knowledge in biochemistry. We study the operation and scope of these strategies by careful historical analysis, reaching a number of systematic conclusions: (1) even basic strategies can illuminate "hard cases" of scientific discovery that go far beyond simple extrapolation or analogy; (2) the causal-mechanistic approach to discovery permits a middle course between the extremes of a completely substrate-neutral and a completely domain-specific view of scientific discovery; (3) the existing literature on mechanism discovery underemphasizes the role of combinatorial approaches in defining and exploring search spaces of possible problem solutions; (4) there is a subtle interplay between a fine-grained mechanistic and a more coarse-grained causal level of analysis, and both are needed to make discovery processes intelligible.

  1. Das Siebente Gebot, das Hohelied und Calvin

    Directory of Open Access Journals (Sweden)

    James A. Loader

    2002-10-01

    Taking the Seventh Commandment (according to the numbering of the Calvinist tradition as its focus, this article examines the hermeneutical principles of the Reformer, John Calvin, for the exposition of the Decalogue. This is related to a consideration of the ‘theological meaning’ of the Book of Canticles (Song of Songs, an Old Testament book which, significantly, does not feature among the commentaries of Calvin. It is argued that the secular impact of the erotic songs is equally strong and meaningful against the backdrop of Hellenistic Jewry, as it is against that of preexilic Israel. It is concluded that the dimension of the Song’s sexual ethic is not an abrogation of the Law, but an extension of it: Here it is not a matter of mere prohibition and consequently, artificial techniques are not necessary in order to distil positive meaning from the negative commandment. Neither is this sexual ethic a matter of exclusive male rights, nor is purity protected at the cost of justice – Eros is taken up in Agape.

  2. Everyone is a winner

    DEFF Research Database (Denmark)

    Reuben, Ernesto; Tyran, Jean-Robert

    2010-01-01

    We test if cooperation is promoted by rank-order competition between groups in which all groups can be ranked first, i.e. when everyone can be a winner. This type of rank-order competition has the advantage that it can eliminate the negative externality a group's performance imposes on other groups....... However, it has the disadvantage that incentives to outperform others are absent, and therefore it does not eliminate equilibria where all groups cooperate at an equal but low level. We find that all-can-win competition produces a universal increase in cooperation and benefits a majority of individuals...

  3. On generalized Melvin solution for the Lie algebra E6

    International Nuclear Information System (INIS)

    Bolokhov, S.V.; Ivashchuk, V.D.

    2017-01-01

    A multidimensional generalization of Melvin's solution for an arbitrary simple Lie algebra G is considered. The gravitational model in D dimensions, D ≥ 4, contains n 2-forms and l ≥ n scalar fields, where n is the rank of G. The solution is governed by a set of n functions H s (z) obeying n ordinary differential equations with certain boundary conditions imposed. It was conjectured earlier that these functions should be polynomials (the so-called fluxbrane polynomials). The polynomials H s (z), s = 1,.., 6, for the Lie algebra E 6 are obtained and a corresponding solution for l = n = 6 is presented. The polynomials depend upon integration constants Q s , s = 1,.., 6. They obey symmetry and duality identities. The latter ones are used in deriving asymptotic relations for solutions at large distances. The power-law asymptotic relations for E 6 -polynomials at large z are governed by the integer-valued matrix ν = A -1 (I + P), where A -1 is the inverse Cartan matrix, I is the identity matrix and P is a permutation matrix, corresponding to a generator of the Z 2 -group of symmetry of the Dynkin diagram. The 2-form fluxes Φ s , s = 1,.., 6, are calculated. (orig.)

  4. Economic and social ethics in the work of John Calvin

    Directory of Open Access Journals (Sweden)

    Matthias Freudenberg

    2009-11-01

    Full Text Available John Calvin and Reformed Protestantism interlinked questions of life and death with questions of faith. Not only faith and the church, but life in general call for constant renewal through the word of God. These processes of renewal incorporate society and the economy. In contrast to the popular assertion that Calvin and Calvinism are responsible for capitalism and its aberrations, Calvin in particular shows a deep sensibility for human beings trapped in economic deprivation. In his sermons Calvin exhorts the rich to consider the poor as ‘their’ poor and to thank God by practicing generosity. This appreciation of social questions within an ecumenical context is demonstrated in the Reformed church in a whole array of charitable services. It will be crucial for the current debate on economic ethics to assess economic processes in relation to how they serve life. For it is liberty, justice and fellowship – as gifts of God – that serve as an orientation and an obligation to be aware of human beings suffering from the negative consequences of globalisation.

  5. The Ideal of Brevitas et Facilitas: The Theological Hermeneutics of John Calvin

    OpenAIRE

    M.J. Ahn

    1999-01-01

    Calvin presented his own distinctive method of the hermeneutics of Scripture in his Commentary on the Epistle of Paul, the Apostle, to the Romans. It is called the ideal of brevitas et facilitas. Calvin was not satisfied with both Malanchthon's loci method and Bucer's prolixity commentary. He took a via media approach. Calvin's method was influenced by rhetoric of Aristotle, Cicero, Quintilian and Chrysostom. Calvin, however, confirmed that his own principle came from Scripture itself. I deal...

  6. The role of the Holy spirit in Calvin's doctrine of the sacraments ...

    African Journals Online (AJOL)

    Calvin has frequently been labeled "the theologian of the Holy Spirit". Although there have been a number of studies of various aspects of the Holy Spirit in Calvin's theology since the significant works of Simon van der Linde (1943) and Werner Krusche (1957), none has dealt with the role the Spirit plays in Calvin's doctrine ...

  7. Calvin, Van Lodenstein and Barth: Three perspectives on the ...

    African Journals Online (AJOL)

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    How to cite: Dreyer, W.A., 2017, 'Calvin, Van Lodenstein and Barth: Three perspectives on the necessity of church reformation', in ..... people were carefully educated about the importance, efficacy, meaning and advantages of .... of lectures at Basel University during 1959 on ecclesia semper reformanda (Bush 2008:290).

  8. Quantum chemical investigation of thermochemistry in Calvin cycle

    Indian Academy of Sciences (India)

    RuBP and ADP.5,6 Goldberg et al. in their series of review papers7–13 consolidated huge experimental data on thermodynamic parameters such as enthalpy change and apparent equilibrium constant of different classes of enzyme-catalyzed reactions from a large number of references. The important steps of Calvin cycle ...

  9. Calvin and other religions: research | Potgieter | Acta Theologica

    African Journals Online (AJOL)

    Widely differing views on ways leading to true knowledge of God is at present characteristic of discussions in the sphere of religion. Although Calvin worked in a completely different scene, he has laid down certain principles based on his interpretation of Holy Scripture that may contribute to current theological thought on ...

  10. Calvin and the confessions of the Reformation | Heron | HTS ...

    African Journals Online (AJOL)

    The historical context of writing in which this Catechism is sketched, its use in Geneva is described, and the outline of the Catechism is mentioned. The article continues to discuss why Calvin thought there was a need for a catechism, and why he wrote it in Latin and sent it to East Friesland. In conclusion the author explains ...

  11. Breast Cancer Startup Challenge winners

    Science.gov (United States)

    Ten winners of a world-wide competition to bring emerging breast cancer research technologies to market faster were announced today by the Avon Foundation for Women, in partnership with NCI and the Center for Advancing Innovation (CAI). Avon is providing

  12. John Calvin on the kingdom of God and eschatology

    Directory of Open Access Journals (Sweden)

    J.H. van Wyk

    2001-08-01

    Full Text Available In this article the author investigates Calvin’s view on the kingdom of God and eschatology. The first question to be answered is: how does one know (anything about eschatology? Calvin’s answer is clear: only through the Word of God. The author continues to illustrate that for Calvin the expectation of the kingdom and the eschaton does not frustrate or annihilate the present, but stimulates and directs human activities. Attention is also paid to the realisation and fulfilment of the kingdom and the esch

  13. Calvin in word and deed: A communicological appreciation

    Directory of Open Access Journals (Sweden)

    D.F. du Plessis

    2001-08-01

    Full Text Available John Calvin’s views on the role of the preacher, as well as the manner in which he applied these views in practice, are examined by using a simplified linear model of communication. Firstly, Calvin’s view on the role of the preacher is examined – as expressed in the Institutes, his letters and commentaries. From a communication perspective, it is clear that, from what Calvin said, he thoroughly saw himself as a servant, relying on the Word of God – a servant who had to execute his assignment in obedience to what God (communicator in the model expected from him as an instrument in His hands. Secondly, in addition to Calvin’s views on his role as a preacher, it was also established how he acted in some demanding situations. The consistency of his thinking was illustrated by comparing what he did to what he said. The examination revealed that Calvin’s action was to bring the Word. Calvin’s actions were therefore consistent with the views articulated in his writings. Thirdly, from his letters to persecuted followers, we can deduce Calvin’s views on the practical application of the ideas which he stated in the Institutes and other publications. The article concludes that, if measured against the simplified linear communication model, it can be assumed that Calvin saw himself as a communication medium or channel used by God to convey His message and not as a communicator following his own agenda.

  14. The question of deification in the theology of John Calvin

    Directory of Open Access Journals (Sweden)

    Sung W. Park

    2017-01-01

    Full Text Available Calvin scholars debate whether Calvin�s theology supports the Eastern Orthodox theosis, which advocates the believers� participation in the intrinsic divine life, mediated by Christ�s humanity in their union with Christ. To attempt to give an answer to the question of theosis in Calvin�s theology, this article isolates a framework used by the proponents of Eastern Orthodox theosis in Calvin�s theology. The framework centres around the three aspects of the nature of the salvific gifts, the nature of the believers� union with Christ and the relation of Christ�s two natures in their hypostatic union. The re-examination of these three aspects through the lens of Calvin�s theology shows that it is hard to hold that Calvin teaches Eastern Orthodox theosis.Intradisciplinary and/or interdisciplinary implication: As a Reformed intradisciplinary assessment of the question of theosis in Calvin�s theology, this article maintains that the proponents of Calvin�s doctrine of theosis overlook his Chalcedonian Christology, the personal dimension of his idea of union with Christ and his emphasis on Christ�s salvific work in his humanity.

  15. Origin and originality of John Calvin's 'Harmony of the law', the ...

    African Journals Online (AJOL)

    It also sheds light on the history of the congrégations, this fascinating example of concentration on the Bible in Geneva, on the co-operation of the ministers, and on Calvin's role as the moderator of the Company of Pastors. The origin of the Harmony idea is an adaptation of the Gospel Harmonies. Calvin's approach is highly ...

  16. Economic and social ethics in the work of John Calvin | Freudenberg ...

    African Journals Online (AJOL)

    John Calvin and Reformed Protestantism interlinked questions of life and death with questions of faith. Not only faith and the church, but life in general call for constant renewal through the word of God. These processes of renewal incorporate society and the economy. In contrast to the popular assertion that Calvin and ...

  17. The Transitional Legend of Winners

    Directory of Open Access Journals (Sweden)

    Ivan Kovačević

    2016-03-01

    Full Text Available During 2006 a number of stories that featured the motive of great gain under dramatic circumstances were repeatedly told in betting-houses in Kragujevac, a town in Serbia. The main character of these legends is an empoverished victim of transition who, thanks to luck and help of friends, wins a great sum of money betting. Besides describing the preceding transitional "fall" of the winner (getting fired, failing in private enterprise, the legends describe his economical and social prosperity initiated by capital gained through betting (starting succesfull enterprises, buying good shares. Diachronically following other "sudden wealth" legends this transitional legend speaks about the establishing of a new system of values that, in the categories of social promotion, makes up for the old principles that marked the period of socialism.

  18. And now, for the winners.

    CERN Multimedia

    Alizée Dauvergne

    2010-01-01

    The Computer Security Day held on 10 June was a success. There were eight presentations, with some forty people attending each session.     The presentation videos can be viewed on Indico. The computer security team’s new website is now up and running, with a wealth of useful information and advice. Go to http://cern.ch/Computer.Security.     The quiz attracted 130 participants, and the answers have now been posted on line! The quiz winners are: Lars Aprin, Richard Baud, Thibaut Bernard, Brice Copy, Daniele de Ruschi, Sébastien Gadrat, Amanda Garcia Munoz, Stephen Gowdy, Joni Hahkala, Joseph Izen, Ryszard Erazm Jurga, Jukka Klem, Danila Oleynik, Ian Pong, Pascal Serge Roguet, Jani Tapani Taskinen, Jan Therhaag, Yves Thurel, Adrian Vogel, Thomas White. Well done to all! If you haven’t done so already, you should soon be getting your prize (i.e. a book, a T-shirt or a bag, etc.).  

  19. Why do winners keep winning? Androgen mediation of winner but not loser effects in cichlid fish

    Science.gov (United States)

    Oliveira, Rui F.; Silva, Ana; Canário, Adelino V.M.

    2009-01-01

    Animal conflicts are influenced by social experience such that a previous winning experience increases the probability of winning the next agonistic interaction, whereas a previous losing experience has the opposite effect. Since androgens respond to social interactions, increasing in winners and decreasing in losers, we hypothesized that socially induced transient changes in androgen levels could be a causal mediator of winner/loser effects. To test this hypothesis, we staged fights between dyads of size-matched males of the Mozambique tilapia (Oreochromis mossambicus). After the first contest, winners were treated with the anti-androgen cyproterone acetate and losers were supplemented with 11-ketotestosterone. Two hours after the end of the first fight, two contests were staged simultaneously between the winner of the first fight and a naive male and between the loser of first fight and another naive male. The majority (88%) of control winners also won the second interaction, whereas the majority of control losers (87%) lost their second fight, thus confirming the presence of winner/loser effects in this species. As predicted, the success of anti-androgen-treated winners in the second fight decreased significantly to chance levels (44%), but the success of androgenized losers (19%) did not show a significant increase. In summary, the treatment with anti-androgen blocks the winner effect, whereas androgen administration fails to reverse the loser effect, suggesting an involvement of androgens on the winner but not on the loser effect. PMID:19324741

  20. And the winners were... Innovation Awards

    CERN Document Server

    2003-01-01

    The winners of the 2003 Economist innovation awards included Tim Berners-Lee for the WWW and Dr. Damadian for his suggestion that NMR could be used as a medical detection device for cancer (1/2 page).

  1. Calvin and Swaab: A comparison with respect to free will

    Directory of Open Access Journals (Sweden)

    Ammiël Meuleman

    2014-12-01

    Full Text Available In theology and philosophy, the issue of free will is being revived. This revival seems to be initiated by the neurosciences, which, at the level of the brain, wants to give a decisive answer about the matter of free will. There are neuroscientists who think that humans are completely determined by their brain functions. The Dutch neurobiologist Dick Swaab therefore calls this‘neurocalvinism’. This article examines whether the two kinds of determinism are compatible. It will be proved that this is not the case and that the neurosciences propagate a stronger kind of determinism than Calvin and that the two therefore are different in principle. Calvijn en Swaab: Een vergelijking met betrekking tot de vrije wil. In de theologie en filosofie is een opleving gaande als het gaat om het denken over de vrije wil. Deze opleving lijkt echter geïnitieerd door de neurobiologie, die op het niveau van de hersencellen hierover uitsluitsel wil geven. Er zijn neurobiologen die aan de hand van dit onderzoek menen dat de mens volledig gedetermineerd is. Deze visie wordt daarom, door de Nederlandse neurobioloog Dick Swaab, ook wel ‘neurocalvinisme’ genoemd. In dit artikel wordt onderzocht of het determinisme van Calvijn en de neurowetenschappen inderdaad kunnen worden uitgewisseld. Aangetoond wordt dat dit niet het geval is en dat de neurowetenschappen een hardere vorm van determinisme voorstaand dan Calvijn en in die zin principieel van elkaar verschillen.

  2. Everyone Is a Winner

    DEFF Research Database (Denmark)

    Reuben, Ernesto; Tyran, Jean-Robert

    In this paper, we study the effectiveness of intergroup competition in promoting cooperative behavior. We focus on intergroup competition that is non-rival in the sense that everyone can be a winner. This type of competition does not give groups an incentive to outcompete others. However, in spit...

  3. Shaping the worship of the Reformed Church in Geneva: Calvin on prayer and praise

    Directory of Open Access Journals (Sweden)

    Alasdair Heron

    2012-11-01

    Full Text Available The article aims to investigate the Calvin’s Genevan Service Order. It focuses on the question how the Psalter Calvin shaped the worship of the Reformed Church in Geneva. The article follows the critical edition of the Genevan prayer in Calvini Opera Selecta and in the German Studienausgabe as the two main published editions of the Genevan order with its related texts. The article shows that Calvin adhered to the general line of the Swiss and Upper German Reformations. It explores the understanding of worship reflected in the Genevan Service Order and the specific significance of its musical aspect. The article illustrates why Calvin gave the psalms the place he did in Genevan Reformed worship.

  4. The significance of Calvin' s anthropology for preaching on ethical themes

    OpenAIRE

    L. O.K. Lategan

    1998-01-01

    In this article the author highlights Calvin's anthropology. A main feature of this anthropology is his dualistic view on man. Calvin was very much influenced by the ancient Greek philosophy, which argued that man had two parts: a superior soul and an inferior body. The author argues that this perception is at odds with a Biblical image of man. According to the Bible no part of man is inferior or superior to any other part of his personhood. The article indicates that a Biblical perspective o...

  5. Winners of student essay contest receive awards

    Science.gov (United States)

    1999-01-01

    At the Apollo/Saturn V Center, George Meguiar (center left) and George English (center right) present scholarships to two students who entered an essay contest in conjunction with the 30th Anniversary of Apollo 11. The winners shown are Kyla Davis Horn, of Cocoa Beach, and Kyle Rukaczewski, of Satellite Beach. A third winner, Jason Gagnon, of Viera, was unable to attend. Meguiar and English head the Apollo 11 Commemoration Association which sponsored the contest in conjunction with Florida Today newspaper. The presentation was made at the Apollo/Saturn V Center during an anniversary banquet that honored all the people who made the Apollo Program possible. Special guests included former Apollo astronauts Neil Armstrong, Edwin 'Buzz' Aldrin, Gene Cernan and Walt Cunningham, who shared their experiences with the audience.

  6. Identifying Winners and Losers in Transportation

    OpenAIRE

    David Levinson

    2002-01-01

    This paper explores the issues surrounding transportation equity for effects both external and internal to transportation. Several examples of transportation "improvements" imposing transportation costs on more individuals than who are benefited are provided. Beyond counting the number of winners and losers, several quantitative measures of equity are suggested. To that end, transportation benefit cost analyses should include an "Equity Impact Statement". This statement would consider the dis...

  7. CERN welcomes Intel Science Fair winners

    CERN Multimedia

    Katarina Anthony

    2012-01-01

    This June, CERN welcomed twelve gifted young scientists aged 15-18 for a week-long visit of the Laboratory. These talented students were the winners of a special award co-funded by CERN and Intel, given yearly at the Intel International Science and Engineering Fair (ISEF).   The CERN award winners at the Intel ISEF 2012 Special Awards Ceremony. © Society for Science & the Public (SSP). The CERN award was set up back in 2009 as an opportunity to bring some of the best and brightest young minds to the Laboratory. The award winners are selected from among 1,500 talented students participating in ISEF – the world's largest pre-university science competition, in which students compete for more than €3 million in awards. “CERN gave an award – which was obviously this trip – to students studying physics, maths, electrical engineering and computer science,” says Benjamin Craig Bartlett, 17, from South Carolina, USA, wh...

  8. On flux integrals for generalized Melvin solution related to simple finite-dimensional Lie algebra

    International Nuclear Information System (INIS)

    Ivashchuk, V.D.

    2017-01-01

    A generalized Melvin solution for an arbitrary simple finite-dimensional Lie algebra G is considered. The solution contains a metric, n Abelian 2-forms and n scalar fields, where n is the rank of G. It is governed by a set of n moduli functions H s (z) obeying n ordinary differential equations with certain boundary conditions imposed. It was conjectured earlier that these functions should be polynomials - the so-called fluxbrane polynomials. These polynomials depend upon integration constants q s , s = 1,.., n. In the case when the conjecture on the polynomial structure for the Lie algebra G is satisfied, it is proved that 2-form flux integrals Φ s over a proper 2d submanifold are finite and obey the relations q s Φ s = 4πn s h s , where the h s > 0 are certain constants (related to dilatonic coupling vectors) and the n s are powers of the polynomials, which are components of a twice dual Weyl vector in the basis of simple (co-)roots, s = 1,.., n. The main relations of the paper are valid for a solution corresponding to a finite-dimensional semi-simple Lie algebra G. Examples of polynomials and fluxes for the Lie algebras A 1 , A 2 , A 3 , C 2 , G 2 and A 1 + A 1 are presented. (orig.)

  9. On generalized Melvin solution for the Lie algebra E{sub 6}

    Energy Technology Data Exchange (ETDEWEB)

    Bolokhov, S.V. [Peoples' Friendship University of Russia (RUDN University), Moscow (Russian Federation); Ivashchuk, V.D. [VNIIMS, Center for Gravitation and Fundamental Metrology, Moscow (Russian Federation); Peoples' Friendship University of Russia (RUDN University), Moscow (Russian Federation)

    2017-10-15

    A multidimensional generalization of Melvin's solution for an arbitrary simple Lie algebra G is considered. The gravitational model in D dimensions, D ≥ 4, contains n 2-forms and l ≥ n scalar fields, where n is the rank of G. The solution is governed by a set of n functions H{sub s}(z) obeying n ordinary differential equations with certain boundary conditions imposed. It was conjectured earlier that these functions should be polynomials (the so-called fluxbrane polynomials). The polynomials H{sub s}(z), s = 1,.., 6, for the Lie algebra E{sub 6} are obtained and a corresponding solution for l = n = 6 is presented. The polynomials depend upon integration constants Q{sub s}, s = 1,.., 6. They obey symmetry and duality identities. The latter ones are used in deriving asymptotic relations for solutions at large distances. The power-law asymptotic relations for E{sub 6}-polynomials at large z are governed by the integer-valued matrix ν = A{sup -1}(I + P), where A{sup -1} is the inverse Cartan matrix, I is the identity matrix and P is a permutation matrix, corresponding to a generator of the Z{sub 2}-group of symmetry of the Dynkin diagram. The 2-form fluxes Φ{sup s}, s = 1,.., 6, are calculated. (orig.)

  10. 76 FR 20034 - Calvin Ramsey, M.D.; Revocation of Registration

    Science.gov (United States)

    2011-04-11

    ... DEPARTMENT OF JUSTICE Drug Enforcement Administration [Docket No. 10-25] Calvin Ramsey, M.D.; Revocation of Registration On December 18, 2009, the Deputy Assistant Administrator, Office of Diversion... constitutional right to appointed counsel in a proceeding under 21 U.S.C. 824(a). See Goldberg v. Kelly, 397 U.S...

  11. CULTURA DA EDUCAÇÃO MATEMÁTICA NAS TIRINHAS “CALVIN E HAROLDO”

    Directory of Open Access Journals (Sweden)

    Davi Mourão Motta Drummond

    2009-12-01

    Full Text Available RESUMO:o artigo discute os elementos da cultura da educação matemática presentes nas tirinhas Calvin e Haroldo, do cartunista americano Bill Watterson, publicadas em jornais de todo o mundo ao longo de dez anos, entre 1985 e 1995, e compiladas em dez livros próprios e em coletâneas. As histórias das tirinhas transpassam temas como: educação matemática, convivência social, relação entre pais e filhos e outros.PALAVRAS-CHAVE: etnomatemática, educação matemática, cultura da aprendizagem, calvin e haroldo.ABSTRACT:Article discusses the elements of mathematics education culture present in strips Calvin and Hobbes, Bill Watterson American cartoonist, published in newspapers around the world over ten years between 1985 and 1995 and compiled in ten own books and collections . The stories of strips trespass topics such as mathematics education, social life, relationship between parents and children and others. KEYWORDS: ethnomathematical, mathematics education, learning culture, Calvin and Hobbes.Recebido: 03/11/2009     Aceito: 17/12/2009

  12. Current views on the regulation of autotrophic carbon dioxide fixation via the Calvin cycle in bacteria

    NARCIS (Netherlands)

    Dijkhuizen, L.; Harder, W.

    1984-01-01

    The Calvin cycle of carbon dioxide fixation constitutes a biosynthetic pathway for the generation of (multi-carbon) intermediates of central metabolism from the one-carbon compound carbon dioxide. The product of this cycle can be used as a precursor for the synthesis of all components of cell

  13. On flux integrals for generalized Melvin solution related to simple finite-dimensional Lie algebra

    Energy Technology Data Exchange (ETDEWEB)

    Ivashchuk, V.D. [VNIIMS, Center for Gravitation and Fundamental Metrology, Moscow (Russian Federation); Peoples' Friendship University of Russia (RUDN University), Institute of Gravitation and Cosmology, Moscow (Russian Federation)

    2017-10-15

    A generalized Melvin solution for an arbitrary simple finite-dimensional Lie algebra G is considered. The solution contains a metric, n Abelian 2-forms and n scalar fields, where n is the rank of G. It is governed by a set of n moduli functions H{sub s}(z) obeying n ordinary differential equations with certain boundary conditions imposed. It was conjectured earlier that these functions should be polynomials - the so-called fluxbrane polynomials. These polynomials depend upon integration constants q{sub s}, s = 1,.., n. In the case when the conjecture on the polynomial structure for the Lie algebra G is satisfied, it is proved that 2-form flux integrals Φ{sup s} over a proper 2d submanifold are finite and obey the relations q{sub s} Φ{sup s} = 4πn{sub s}h{sub s}, where the h{sub s} > 0 are certain constants (related to dilatonic coupling vectors) and the n{sub s} are powers of the polynomials, which are components of a twice dual Weyl vector in the basis of simple (co-)roots, s = 1,.., n. The main relations of the paper are valid for a solution corresponding to a finite-dimensional semi-simple Lie algebra G. Examples of polynomials and fluxes for the Lie algebras A{sub 1}, A{sub 2}, A{sub 3}, C{sub 2}, G{sub 2} and A{sub 1} + A{sub 1} are presented. (orig.)

  14. Winners and Losers of Danish Football

    DEFF Research Database (Denmark)

    Storm, Rasmus K.

    performance outputs in relation to key factors of this function. The approach reflected represents a sociological supplement to the ordinary performance benchmarks often used in sports economics, revealing FC København and Brøndby IF as the main winners and AGF and Akademisk Boldklub (AB) as main losers......This paper deals with European and Danish soccer and its commercialization focusing on the Danish male first tier clubs. Based on the systems theoretical argument that sport serves as a mirror system in (late-) modern society, the Danish football clubs are measured against a simple matrix of main...

  15. The significance of Calvin' s anthropology for preaching on ethical themes

    Directory of Open Access Journals (Sweden)

    L. O.K. Lategan

    1998-12-01

    Full Text Available In this article the author highlights Calvin's anthropology. A main feature of this anthropology is his dualistic view on man. Calvin was very much influenced by the ancient Greek philosophy, which argued that man had two parts: a superior soul and an inferior body. The author argues that this perception is at odds with a Biblical image of man. According to the Bible no part of man is inferior or superior to any other part of his personhood. The article indicates that a Biblical perspective on anthropology will draw different conclusions in ethics compared to a dualistic perception of the nature of man. A correct appreciation of the anthropology of man is therefore needed to guide decisions in ethics, where the focus is constantly anthropological.

  16. Perspectives on the doctrine of providence in some of Calvin' s sermons on Job

    Directory of Open Access Journals (Sweden)

    Pieter C. Potgieter

    1998-12-01

    Full Text Available It is quite remarkable that Calvin addresses himself to the providence of God not only in his 'theological' works (eg Institutes, but particularly also in his more 'popular' works, for instance his correspondence and sermons. This is where the doctrine of providence is significantly contextualized. It is obvious that he takes up his topic in a most responsible manner, by which the 'providentia Dei' should not only comfort those who believe in Christ, but should also call for a responsible life before the countenance of God. Furthermore, for Calvin providence is not so much an issue to be 'explained', but rather a 'confession' related to the very heart of faith.

  17. Law and Gospel or Gospel and Law? Karl Barth, Martin Luther and John Calvin

    Directory of Open Access Journals (Sweden)

    I. John Hesselink

    2012-05-01

    Full Text Available For Calvin the order of the law-gospel relation may be put this way: Law of creation (natural law – revealed law (the law of Moses – the gospel – the gracious law (third use as a norm and guide for believers. The same outline would follow for Luther except that the third or positive use of the law plays a minor role in his thinking. On the surface Barth would seem to have more affinity with Calvin but the differences are significant because of Barth’s rejection of any notion of the antithesis of law and gospel and his subsuming the law in all its functions under God’s grace.

  18. Calvin 1 5 preaching on the church in the letter to the Ephesians

    Directory of Open Access Journals (Sweden)

    S. J. Botha

    1998-12-01

    Full Text Available Dealing with Calvin as preacher inevitably involves attention to his preaching on the church. With this purpose in mind, three sermons from the letter to the Ephesians are analyzed. In this paper the results are discussed under three main headings, namely the origin and the essence of the church, the unity of the church and the offices of the church.

  19. The glucose 6-phosphate shunt around the Calvin-Benson cycle.

    Science.gov (United States)

    Sharkey, Thomas D; Weise, Sean E

    2016-07-01

    It is just over 60 years since a cycle for the regeneration of the CO2-acceptor used in photosynthesis was proposed. In this opinion paper, we revisit the origins of the Calvin-Benson cycle that occurred at the time that the hexose monophosphate shunt, now called the pentose phosphate pathway, was being worked out. Eventually the pentose phosphate pathway was separated into two branches, an oxidative branch and a non-oxidative branch. It is generally thought that the Calvin-Benson cycle is the reverse of the non-oxidative branch of the pentose phosphate pathway but we describe crucial differences and also propose that some carbon routinely passes through the oxidative branch of the pentose phosphate pathway. This creates a futile cycle but may help to stabilize photosynthesis. If it occurs it could explain a number of enigmas including the lack of complete labelling of the Calvin-Benson cycle intermediates when carbon isotopes are fed to photosynthesizing leaves. © The Author 2015. Published by Oxford University Press on behalf of the Society for Experimental Biology. All rights reserved. For permissions, please email: journals.permissions@oup.com.

  20. Calvin, Augustine of Hippo and South Africa: in discussion with Johannes van Oort

    Directory of Open Access Journals (Sweden)

    J.W. Hofmeyr

    2010-07-01

    Full Text Available In this article the curtain is raised on the interesting and fascinating relation between Augustine of Hippo and John Cal- vin from Geneva, as seen through the eyes of the Dutch scholar Johannes van Oort. The influences of and links between Augustine and Calvin are immense. This has been the focus of various studies in the past. The purpose of this article is, however, not to re-invent the wheel about these relations, but rather to reflect on one of the most eminent scholars on Augustine, i.e. Van Oort’s vision on these links and to enter into a dialogue with him so as to shed some new light on this topic and on some aspects related to ecclesiology. After attention to the use of Augustine by Calvin, the focus is on the discussion with Van Oort and eventually on the relevance of this for us in South(ern Africa. It is concluded that in this era of post- modernism and relativism as well much can be learnt from both Augustine and Calvin, and especially with regard to the well- being of the church.

  1. Google Science Fair winner visits CERN

    CERN Multimedia

    Katarina Anthony

    2012-01-01

    Google Science Fair Grand Prize winner Brittany Michelle Wenger today wrapped up a day-and-a-half's visit of the CERN site. Her winning project uses an artificial neural network to diagnose breast cancer – a non-invasive technique with significant potential for use in hospitals.   Brittany Michelle Wenger at CERN's SM18 Hall. Besides winning a $50,000 scholarship from Google and work experience opportunities with some of the contest hosts, Brittany was offered a personal tour of CERN. “This visit has just been incredible,” she says. “I got to speak with [CERN's Director for Accelerators and Technology] Steve Myers about some of the medical applications and technologies coming out of the LHC experiments and how they can be used to treat cancer. We talked about proton therapy and hadron therapy, which could really change the way patients are treated, improving success rates and making treatment not such an excruciating process. That ...

  2. Sweet Sweetback’s Baadasssss Song de Melvin Van Peebles (1971 : exégèse d’un film militant Sweet Sweetback’s Baadasssss Song by Melvin Van Peebles (1971: An Analysis of a Militant Movie

    Directory of Open Access Journals (Sweden)

    Delphine Letort

    2009-07-01

    Full Text Available Sweet Sweetback’s Baadasssss Song represented a turning point in filmmaking when it was released in 1971. This article focuses on the interplay of the political and the aesthetic in a film that was conceived as a means of furthering change in the representation of African Americans. Not only did it support the emergence of black cinema by opening up filmmaking to black crews, but it also broached taboo subjects while depicting black sexuality (miscegenation and police brutality. Melvin Van Peebles proposed a new heroic figure through the character of Sweetback, whose hypersexuality was to become a mercantile asset in Hollywood blaxploitation films. Nevertheless, the narrative’s reliance on a stereotypical Sweetback undermined its political message.

  3. 2016 Federal Green Challenge Award Winners in the Southeast Region

    Science.gov (United States)

    2016 FGC award winners in the Southeast are: the Department of Human Services’ U.S. Citizenship and Immigration Services Southeast Regional Office and Department of Energy’s East Tennessee Technology Park.

  4. Winners and losers of IWRM in Tanzania

    Directory of Open Access Journals (Sweden)

    Barbara van Koppen,

    2016-10-01

    Full Text Available This paper focuses on the application of the concept of Integrated Water Resources Management (IWRM in Tanzania. It asks: how did IWRM affect the rural and fast-growing majority of smallholder farmersʼ access to water which contributes directly to poverty alleviation and employment creation in a country where poverty and joblessness are high? Around 1990, there were both a strong government-led infrastructure development agenda and IWRM ingredients in place, including cost-recovery of state services aligning with the Structural Adjustment Programmes, water management according to basin boundaries and the dormant colonial water rights (permits system. After the 1990s, the World Bank and other donors promoted IWRM with a strong focus on hydroelectric power development, River Basin Water Boards, transformation of the water right system into a taxation tool, and assessment of environmental flows. These practices became formalised in the National Water Policy (2002 and in the Water Resources Management Act (2009. Activities in the name of IWRM came to be closely associated with the post-2008 surge in large-scale land and water deals. Analysing 25 years of IWRM, the paper identifies the processes and identities of the losers (smallholders and – at least partially – the government and the winners (large-scale water users, including recent investors. We conclude that, overall, IWRM harmed smallholdersʼ access to water and rendered them more vulnerable to poverty and unemployment.

  5. THE CALVIN CYCLE ENZYME PHOSPHOGLYCERATE KINASE OF XANTHOBACTER-FLAVUS REQUIRED FOR AUTOTROPHIC CO2 FIXATION IS NOT ENCODED BY THE CBB OPERON

    NARCIS (Netherlands)

    MEIJER, WG

    1994-01-01

    During autotrophic growth of Xanthobacter flavus, energy derived from the oxidation of hydrogen methanol or formate is used to drive the assimilation of CO2 via the Calvin cycle. The genes encoding the Calvin cycle enzymes are organized in the cbb operon, which is expressed only during autotrophic

  6. ‘”Wipe out lines of Division (Not Distinctions)’ : Bennie Keet, Neo-Calvinism and the Struggle against Apartheid’

    NARCIS (Netherlands)

    Harinck, George

    2017-01-01

    Race was not a dominant factor in neo-Calvinism. Rather, stress was laid on the universal character of Christianity, especially in the case of Herman Bavinck. While some of the South African PhD students at the Vrije Universiteit's defended apartheid with reference to neo-Calvinism, it was B.B. Keet

  7. CERNland/Prince of Asturias competition winners tour CERN

    CERN Multimedia

    Katarina Anthony

    2014-01-01

    Last week, the Laboratory rolled out the red carpet for the six young winners of the CERNland/Prince of Asturias competition. From a visit of the CMS detector to dessert with the Director-General, these young talents were given the full VIP treatment. Nothing less would do for our winners!   The competition's youngest winners study the CMS detector. For the CERNland/Prince of Asturias competition winners, Easter 2014 would be unforgettable. Besides visits to all the main CERN landmarks, they attended an award ceremony in the Main Building in their honour. Among the audience were CERN Director-General, Rolf Heuer, the Permanent Representative of Spain to the United Nations Office at Geneva, Ana Maria Menendez Perez, and the Director of the Prince of Asturias Foundation, Teresa Sanjurjo González. The ceremony was also an opportunity for the CERN community to interact with the young winners. “They brought with them such heartfelt enthusiasm,” says CERN&am...

  8. A conversation with Andrew Benson: reflections on the discovery of the Calvin-Benson cycle.

    Science.gov (United States)

    Benson, Andrew

    2013-03-01

    On June 26-27, 2012, one of us (BBB) made a video based on an interview conducted with Andrew A. Benson, Professor Emeritus, Scripps Institution of Oceanography, University of California, San Diego, CA, USA. The video was first shown in a seminar presented by BBB on July 27, 2012 at the Calvin Laboratory, University of California, Berkeley, to mark the departure of the Energy Biosciences Institute to a new building. Here we record the conversation taking place during the interview. The Brancraft Library on the Berkeley campus will house the video's transcript in its oral histories collection, and the video will be housed in its motion picture collection. The video and the transcript have also been posted on You Tube (http://youtu.be/GfQQJ2vR_xE).

  9. The ministry of the Word – the concept of doctrina as used by Calvin in his first Institutes (1536

    Directory of Open Access Journals (Sweden)

    V.E. d’Assonville

    2001-08-01

    Full Text Available Among other important theological concepts (e.g. religio or iustificatio, etc. the concept of doctrina and its usage concern the heart of Reformational theology – especially in the theology of John Calvin. In spite of some important investigations that have already been undertaken in this regard, there is still a deficiency in respect of a comprehensive theological investigation of this theme. The fact that some well-known contemporary scholars nevertheless do not pay attention to the respective and different cardinal usages of doctrina by Calvin, underlines the need for further research. It is of considerable importance to analyse the way Calvin used the concept of doctrina, not only in a dogmatic and dogmen-historical sense but also with regard to homiletics, catechetics and pastoral care. In this article the focus is on the 1536 edition of the Institutes of Calvin. Using an adequate method to analyse Calvin’s usage, the results of such an analysis are presented in order to emphasise the importance of a careful dealing with concepts in general and in dealing with Calvin’s usage of doctrina in particular. This investigation shows that Calvin used doctrina in such an active and dynamic way that one often has to translate it with a verb, a verbalised noun or even with a verbal phrase. It is of utmost importance to distinguish between Calvin’s lexical usage and his discourse-analytical usage of the concept. Calvin’s bond to Scripture and his stressing of doctrina as proclamation accentuate his “Word-of-God-theology”.

  10. The emergence of John Calvin as pastoral figure from his letters

    Directory of Open Access Journals (Sweden)

    Raymond Potgieter

    2014-11-01

    Full Text Available The gaunt austere figure of John Calvin portrayed in paintings is often synonymous with the view of a stern, authoritarian, dogmatic person, and a strict disciplinarian. Discovery of a more complex figure, however, awaits anyone dipping into Calvin’s letters, in particular when writing pastorally to comfort, encourage, point towards hope and so forth. However, this is no second figure emerging – merely a more balanced portrait of a servant of God who has not always been fairly portrayed. This portrait must be seen as closely associated with his writings. Because theology is for the nurture and maturing of the Church and therefore cannot be divorced from it, the pastoral nature of some incidents does, however, allow the humanity of Calvin to shine through more clearly. Johannes Calvyn: Meer as ‘n sistematiese teoloog. Johannes Calvyn se skraal asketiese voorkoms soos in skilderye uitgebeeld, skep dikwels die indruk van ‘n stroewe, dogmatiese en dissiplinêre figuur. Uit sy briewe en veral uit sy pastorale geskrifte blyk dit egter dat hy ‘n warm en gevoelvolle persoon was wat mense getroos, bemoedig en hoop gegee het. Dit is nie ’n nuwe voorstelling van Calvyn nie, maar bloot ’n meer gebalanseerde beeld van die bekende dienskneg van God wat nie altyd getrou voorgehou is nie. Trouens, hierdie getrouer beeld van hom word deur sy ander geskrifte onderskryf. Omdat teologie onder meer oor die pastorale opvoeding en opbouing van die Kerk gaan, kan daar ook met ’n oop gemoed na hierdie eienskappe van Calvyn in sy teologiese geskrifte gesoek word. Dit is juis die ontdekking van hierdie eienskappe in Calvyn se geskrifte wat daartoe bydra dat sy medemenslikheid duideliker sigbaar word.

  11. Winners & Sinners: What's Hot and What's Not in Alumni Merchandising.

    Science.gov (United States)

    Larson, Wendy Ann

    1990-01-01

    A large part of any merchandising program is picking products that will sell. Sixty alumni professionals were asked about their ideas. Some of the winners included a watch with the institution's seal, a windsock, and athletic shoes. Some of the losers included a sweater and a commemorative plate. (MLW)

  12. Hybrid All-Pay and Winner-Pay Contests

    DEFF Research Database (Denmark)

    Lagerlöf, Johan

    2017-01-01

    In many contests in economic and political life, both all-pay and winner-pay expenditures matter for winning. This paper studies such hybrid contests under symmetry and asymmetry. The symmetric model is very general but still yields a simple closed-form solution. More contestants tend to lead to ...

  13. Steven MacCall: Winner of LJ's 2010 Teaching Award

    Science.gov (United States)

    Berry, John N., III

    2010-01-01

    This article profiles Steven L. MacCall, winner of "Library Journal's" 2010 Teaching Award. An associate professor at the School of Library and Information Studies (SLIS) at the University of Alabama, Tuscaloosa, MacCall was nominated by Kathie Popadin, known as "Kpop" to the members of her cohort in the online MLIS program at SLIS. Sixteen of…

  14. 40 CFR 105.15 - How are award winners recognized?

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 21 2010-07-01 2010-07-01 false How are award winners recognized? 105.15 Section 105.15 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) WATER... ceremony as recognition for an outstanding technological achievement or an innovative process, method or...

  15. Winners of the 2017 IDRC Doctoral Research Awards | IDRC ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    2017-11-30

    Nov 30, 2017 ... Michelle Savard, a 2016 awardee, hands out a certificate for the completion of an entrepreneurial training program that she arranged for war-affected single mothers in Uganda. IDRC is pleased to announce the winners of the 2017 IDRC Doctoral Research Awards. Awardees will conduct field research in ...

  16. Differential Expression of Genes of the Calvin-Benson Cycle and its Related Genes During Leaf Development in Rice.

    Science.gov (United States)

    Yamaoka, Chihiro; Suzuki, Yuji; Makino, Amane

    2016-01-01

    To understand how the machinery for photosynthetic carbon assimilation is formed and maintained during leaf development, changes in the mRNA levels of the Calvin-Benson cycle enzymes, ribulose-1,5-bisphosphate carboxylase/oxygenase (Rubisco) activase and two key enzymes for sucrose synthesis were determined in rice (Oryza sativa L.). According to the patterns of changes in the mRNA levels, these genes were categorized into three groups. Group 1 included most of the genes involved in the carboxylation and reduction phases of the Calvin-Benson cycle, as well as three genes in the regeneration phase. The mRNA levels increased and reached maxima during leaf expansion and then rapidly declined, although there were some variations in the residual mRNA levels in senescent leaves. Group 2 included a number of genes involved in the regeneration phase, one gene in the reduction phase of the Calvin-Benson cycle and one gene in sucrose synthesis. The mRNA levels increased and almost reached maxima before full expansion and then gradually declined. Group 3 included Rubisco activase, one gene involved in the regeneration phase and one gene in sucrose synthesis. The overall pattern was similar to that in group 2 genes except that the mRNA levels reached maxima after the stage of full expansion. Thus, genes of the Calvin-Benson cycle and its related genes were differentially expressed during leaf development in rice, suggesting that such differential gene expression is necessary for formation and maintenance of the machinery of photosynthetic carbon assimilation. © The Author 2015. Published by Oxford University Press on behalf of Japanese Society of Plant Physiologists. All rights reserved. For permissions, please email: journals.permissions@oup.com.

  17. Alert with destruction of stratospheric ozone: 95 Nobel Prize Winners

    International Nuclear Information System (INIS)

    Santamaria, J.; Zurita, E.

    1995-01-01

    After briefly summarizing the discoveries of the 95 Nobel Prize Winners in Chemistry related to the threats to the ozone layer by chemical pollutants, we make a soft presentation of the overall problem of stratospheric ozone, starting with the destructive catalytic cycles of the pollutant-based free radicals, following with the diffusion mathematical models in Atmospheric Chemistry, and ending with the increasing annual drama of the ozone hole in the Antarctica. (Author)

  18. Spring Research Festival and NICBR Collaboration Winners Announced | Poster

    Science.gov (United States)

    By Carolynne Keenan, Contributing Writer, and Ashley DeVine, Staff Writer The winners of the 2014 Spring Research Festival (SRF), held May 7 and 8, were recognized on July 2, and included 20 NCI at Frederick researchers: Matthew Anderson, Victor Ayala, Matt Bess, Cristina Bergamaschi, Charlotte Choi, Rami Doueiri, Laura Guasch Pamies, Diana Haines, Saadia Iftikhar, Maria Kaltcheva, Wojciech Kasprzak, Balamurugan Kuppusamy, James Lautenberger, George Lountos, Megan Mounts, Uma Mudunuri, Martha Sklavos, Gloriana Shelton, Alex Sorum, and Shea Wright.

  19. Sing to the Lord a New Song: John Calvin and the Spiritual Discipline of Metrical Psalmody

    Directory of Open Access Journals (Sweden)

    Brandon J. Bellanti

    2014-11-01

    Full Text Available The purpose of this essay is to evaluate the way that psalmody - specifically metrical psalmody - serves as a sort of spiritual discipline. In other words, this essay seeks to demonstrate how the singing of psalms can be a tool to aid in spiritual growth. Much of the research for this essay focuses on the theological writings of the Protestant reformer John Calvin, as well as the way in which he incorporated metrical psalmody into his liturgical framework. The research also comprises primary writings from Aristotle, Plato, Saint John Chrysostom, Saint Basil, and Saint Augustine - all of whom influenced Calvin’s own philosophy regarding the use of art, music, and psalmody in worship. Additional areas examined in this research include the historical musical development of psalmody and the collection and arrangement of metrical psalms into psalters. For reference, specific examples of metrical psalms and psalters have been added. These additional areas and examples help to give a more holistic understanding of the nature of metrical psalmody, and they help to show how it may accurately be considered a spiritual discipline.

  20. John Calvin and John Locke on the Sensus Divinitatis and Innatism

    Directory of Open Access Journals (Sweden)

    J. Caleb Clanton

    2017-02-01

    Full Text Available Inheritors of the Calvinist Reformed tradition have long disagreed about whether knowledge of God’s nature and existence can be or need be acquired inferentially by means of the standard arguments of natural theology. Nonetheless, they have traditionally coalesced around the thought that some sense or awareness of God is naturally implanted or innate in human beings. A root of this orientation can be found in John Calvin’s discussion of the sensus divinitatis in the first book of The Institutes of the Christian Religion. This paper outlines a pedagogical strategy for organizing and evaluating Calvin’s treatment of the sensus divinitatis, chiefly by putting it in tension with John Locke’s polemic against innatism in Book I of An Essay concerning Human Understanding. I begin by reconstructing Calvin’s depiction of the sensus divinitatis, as well as his case for thinking that it is innate. I then explain how Locke’s critique of innatism offers a fairly direct response to Calvin and, hence, a useful framework for exploring the limits of Calvin’s treatment of the sensus divinitatis.

  1. 2. Melvine.pmd

    African Journals Online (AJOL)

    chifaou.amzat

    2012-12-17

    Dec 17, 2012 ... Given the challenges families face with the array of privacy concerns and ..... A ripple effect is the conscious awareness of masculine hegemony and the competition over female adolescents as commodities among male .... Internet, which is increasingly becoming accessible to adolescents in urban areas in ...

  2. Final Report for research on The Glucose 6-Phosphate Shunt Around the Calvin-Benson Cycle

    Energy Technology Data Exchange (ETDEWEB)

    Sharkey, Thomas D. [Michigan State Univ., East Lansing, MI (United States)

    2017-10-30

    In this research, photosynthetic carbon metabolism was studied to identify mechanisms by which plants store energy from sunlight as carbon compounds, especially sugars. Conditions were identified in which carbon appeared to flow backwards from outside the photosynthetic compartment (chloroplast) back into it. A specific gene product was manipulated to make the flow bigger or smaller. Preventing the flow (by eliminating the gene) had little effect on plant growth but increasing the flow, by overexpressing the gene, caused the plants to become extremely sensitive to changes in light. Plants with the gene overexpressed had high rates of cyclic electron flow, the photosynthetic electron transport pathway that occurs when plants need more of the energy molecule ATP. These and other observations led us to conclude that a metabolic pathway that is normally turned off because it is counter-productive during photosynthesis, in fact occurs at about 10% of the rate of normal photosynthesis. This creates an inefficiency but may stabilize photosynthesis allowing it to cope with the very large and rapid changes that leaves experience such as the hundred-fold changes in light intensity that can occur in seconds on a partly cloudy day. We also concluded that the back flow of carbon into chloroplasts could be important at high rates of photosynthesis allowing increased rates of starch synthesis. Starch synthesis allows plants to store sugars during the day for use at night. At high rates of photosynthesis starch synthesis becomes very important to protect against end-product inhibition of photosynthesis. This research identified two metabolic pathways that extend the primary carbon fixation pathway called the Calvin-Benson cycle. These pathway extensions are now called the cytosolic bypass and the glucose 6-phosphate shunt. This improvement in our understanding of carbon metabolism of photosynthesis will guide efforts to increase photosynthesis to increase production of food, fuel

  3. Carbon dioxide fixation by Calvin-Cycle enzymes improves ethanol yield in yeast.

    Science.gov (United States)

    Guadalupe-Medina, Víctor; Wisselink, H Wouter; Luttik, Marijke Ah; de Hulster, Erik; Daran, Jean-Marc; Pronk, Jack T; van Maris, Antonius Ja

    2013-08-29

    Redox-cofactor balancing constrains product yields in anaerobic fermentation processes. This challenge is exemplified by the formation of glycerol as major by-product in yeast-based bioethanol production, which is a direct consequence of the need to reoxidize excess NADH and causes a loss of conversion efficiency. Enabling the use of CO2 as electron acceptor for NADH oxidation in heterotrophic microorganisms would increase product yields in industrial biotechnology. A hitherto unexplored strategy to address this redox challenge is the functional expression in yeast of enzymes from autotrophs, thereby enabling the use of CO2 as electron acceptor for NADH reoxidation. Functional expression of the Calvin cycle enzymes phosphoribulokinase (PRK) and ribulose-1,5-bisphosphate carboxylase (Rubisco) in Saccharomyces cerevisiae led to a 90% reduction of the by-product glycerol and a 10% increase in ethanol production in sugar-limited chemostat cultures on a mixture of glucose and galactose. Co-expression of the Escherichia coli chaperones GroEL and GroES was key to successful expression of CbbM, a form-II Rubisco from the chemolithoautotrophic bacterium Thiobacillus denitrificans in yeast. Our results demonstrate functional expression of Rubisco in a heterotrophic eukaryote and demonstrate how incorporation of CO2 as a co-substrate in metabolic engineering of heterotrophic industrial microorganisms can be used to improve product yields. Rapid advances in molecular biology should allow for rapid insertion of this 4-gene expression cassette in industrial yeast strains to improve production, not only of 1st and 2nd generation ethanol production, but also of other renewable fuels or chemicals.

  4. An engineered Calvin-Benson-Bassham cycle for carbon dioxide fixation in Methylobacterium extorquens AM1.

    Science.gov (United States)

    von Borzyskowski, Lennart Schada; Carrillo, Martina; Leupold, Simeon; Glatter, Timo; Kiefer, Patrick; Weishaupt, Ramon; Heinemann, Matthias; Erb, Tobias J

    2018-04-03

    Organisms are either heterotrophic or autotrophic, meaning that they cover their carbon requirements by assimilating organic compounds or by fixing inorganic carbon dioxide (CO 2 ). The conversion of a heterotrophic organism into an autotrophic one by metabolic engineering is a long-standing goal in synthetic biology and biotechnology, because it ultimately allows for the production of value-added compounds from CO 2 . The heterotrophic Alphaproteobacterium Methylobacterium extorquens AM1 is a platform organism for a future C1-based bioeconomy. Here we show that M. extorquens AM1 provides unique advantages for establishing synthetic autotrophy, because energy metabolism and biomass formation can be effectively separated from each other in the organism. We designed and realized an engineered strain of M. extorquens AM1 that can use the C1 compound methanol for energy acquisition and forms biomass from CO 2 by implementation of a heterologous Calvin-Benson-Bassham (CBB) cycle. We demonstrate that the heterologous CBB cycle is active, confers a distinct phenotype, and strongly increases viability of the engineered strain. Metabolic 13 C-tracer analysis demonstrates the functional operation of the heterologous CBB cycle in M. extorquens AM1 and comparative proteomics of the engineered strain show that the host cell reacts to the implementation of the CBB cycle in a plastic way. While the heterologous CBB cycle is not able to support full autotrophic growth of M. extorquens AM1, our study represents a further advancement in the design and realization of synthetic autotrophic organisms. Copyright © 2018. Published by Elsevier Inc.

  5. Google Science Fair 2012 : Grand Prize Winner Brittany Wenger

    CERN Multimedia

    Maximilien Brice

    2012-01-01

    17-18 age category AND Grand Prize Winner: Brittany Wenger (USA)—“Global Neural Network Cloud Service for Breast Cancer.” Brittany’s project harnesses the power of the cloud to help doctors accurately diagnose breast cancer. Brittany built an application that compares individual test results to an extensive dataset stored in the cloud, allowing doctors to assess tumors using a minimally-invasive procedure. Brittany Michelle Wenger, and her mother, passed through the CERN Control Centre accompanied by Mike Lamont, CERN Beams Department, Operation Group Leader.

  6. [Women in natural sciences--Nobel Prize winners].

    Science.gov (United States)

    Zuskin, Eugenija; Mustajbegović, Jadranka; Lipozencić, Jasna; Kolcić, Ivana; Spoljar-Vrzina, Sanja; Polasek, Ozren

    2006-01-01

    Alfred Bernhard Nobel was the founder of the Nobel Foundation, which has been awarding world-known scientists since 1901, for their contribution to the welfare of mankind. The life and accomplishments of Alfred Bernhard Nobel are described as well as scientific achivements of 11 women, Nobel prize winners in the field of physics, chemistry, physiology and/or medicine. They are Marie Sklodowska Curie, Maria Goeppert Mayer, Irene Joliot-Curie, Dorothy Crowfoot Hodgkin, Gerty Theresa Radnitz Cori, Rosalyn Sussman Yalow, Barbara McClintock, Rita Levi-Montalcini, Gertrude Elion, Christine Nusslein-Volhard and Linda B. Buck.

  7. The Google Science Fair winner comes to CERN

    CERN Multimedia

    CERN Bulletin

    2011-01-01

    Shree Bose, the Google Science Fair Grand Prize winner, will come to CERN for a three-day internship. She is looking forward to it and hopes to sit in the CERN Control Room, and to learn more about ALICE and in general the work going on here right now.   Google Science Fair winners Lauren Hodge (left) Shree Bose (middle) and Naomi Shah (right). (Image Copyright Google) Despite her young age, Shree Bose is already an experienced researcher. Indeed, she has already been awarded prestigious prizes in various science fairs and competitions. Aged 17, she found a way to improve ovarian cancer treatment for patients when they have built up a resistance to certain chemotherapy drugs. The project won the Grand Prize at the Google Science Fair, and together with an amazing 10-day trip to the Galapagos Islands with National Geographic Expeditions, she also won a trip to CERN. “Shree will visit several experimental sites here and will sit next to our physicists and engineers, in the CCC an...

  8. Nobel prize-winner Heinrich Rohrer visits CERN

    CERN Multimedia

    2008-01-01

    The Nobel prize-winner Heinrich Rohrer met young scientists on a recent visit to the Laboratory. From left to right: Xavier Gréhant (CERN Openlab), Ewa Stanecka (ATLAS), Magda Kowalska (ISOLDE), Heinrich Rohrer, Stéphanie Beauceron (CMS) and Ana Gago Da Silva (UNOSAT).Heinrich Rohrer, who shared the 1986 Nobel prize for physics with Gerd Binnig for the design of the scanning tunnelling microscope, visited CERN on 25 June. Welcomed by the Director-General, Robert Aymar, he visited the ATLAS cavern and control room, the Computer Centre, the Unosat project, the Antimatter Decelerator and ISOLDE. At the end of his visit, he voiced his admiration for CERN and its personnel. As a renowned Nobel prize-winner Heinrich Rohrer has the opportunity to pass on his experience and enthusiasm to young scientists. During the evening meal, at which he met five young physicists and computer scientists, who were delighted with the chance to talk to him, he stressed the importance for re...

  9. Wins, winning and winners: the commercial advertising of lottery gambling.

    Science.gov (United States)

    McMullan, John L; Miller, Delthia

    2009-09-01

    This study analyzed a sample of 920 lottery ads that were placed or played in Atlantic Canada from January 2005 to December 2006. A content analysis, involving quantitative and qualitative techniques, was conducted to examine the design features, exposure profiles and focal messages of these ads and to explore the connections between lottery advertising and consumer culture. We found that there was an "ethos of winning" in these commercials that provided the embedded words, signs, myths, and symbols surrounding lottery gambling and conveyed a powerful imagery of plentitude and certitude in a world of potential loss where there was little reference to the actual odds of winning. The tangible and emotional qualities in the ads were especially inviting to young people creating a positive orientation to wins, winning and winners, and lottery products that, in turn, reinforced this form of gambling as part of youthful consumption practices. We concluded that enticing people with the prospects of huge jackpots, attractive consumer goods and easy wins, showcasing top prize winners, and providing dubious depictions that winning is life-changing was narrow and misleading and exploited some of the factors associated with at-risk gambling.

  10. Regulation of the Calvin-Benson-Bassham cycle in the enigmatic diatoms: biochemical and evolutionary variations on an original theme.

    Science.gov (United States)

    Jensen, Erik; Clément, Romain; Maberly, Stephen C; Gontero, Brigitte

    2017-09-05

    In Plantae, the Calvin-Benson-Bassham (CBB) cycle is highly regulated and most of its enzymes have been thoroughly studied. Since diatoms arose as a result of secondary endosymbiosis with one or more Plantae ancestors, their precise evolutionary history is enigmatic and complex resulting in biochemical variations on the original CBB cycle theme. The Rubisco Michaelis constant for CO 2 is higher in diatoms than land plants and the nuclear-encoded Rubisco activase in Plantae is replaced by an analogous chloroplast-encoded CbbX (Calvin-Benson-Bassham protein X) in diatoms. In the CBB cycle reduction phase, phosphoglycerate kinase in diatoms is redox-regulated and similar to that in red algae; however, glyceraldehyde phosphate dehydrogenase (GAPDH) is not redox-regulated, unlike in Plantae. The phosphoribulokinase (PRK)-GAPDH-CP12 complex found in many photosynthetic organisms has not yet been found in diatoms, but a ferredoxin-NADP reductase (FNR)-GAPDH-CP12 complex has been found in one species. In the CBB cycle regeneration phase, sedoheptulose 1,7-bisphosphatase and PRK are not redox-regulated in diatoms, unlike in Plantae. Regulation at the transcriptional level seems to be important in diatoms. CBB cycle enzyme properties appear to be variable among diatoms, but this view relies on results from a few model species: a greater range of diatoms need to be studied to test this.This article is part of the themed issue 'The peculiar carbon metabolism in diatoms'. © 2017 The Author(s).

  11. Characterizing and modelling persistence in the number of lottery winners

    Science.gov (United States)

    Antonio, Fernando J.; Mendes, Renio S.; Itami, Andreia S.; Picoli, Sergio

    2015-06-01

    Lottery is the most famous branch among all the games of chance. By analysing data from Mega-Sena, the major lottery in Brazil, we investigated the presence of persistent behaviour in the time series of the number of winners. We found that the demand for tickets grew collectively as an exponential driven by the size of the accumulated jackpot. Finally, we identified that a stochastic model grounded on the rolling-over feature of lotteries can generate correlations qualitatively similar to those observed empirically. The model is consistent with the idea that the growth in the number of bets, motivated by the size of the expected jackpot, is a mechanism generator of correlations in an apparently random scenario.

  12. CERN visit for a Norwegian Prize-winner

    CERN Multimedia

    2002-01-01

    One of the prize-winners of the Contest «Life in the Universe», the final of which was held at CERN during the Science and Technology Week in November 2001 (See Bulletin n°47/2002), came to CERN to receive his prize last June. The 15-year old Norwegian Ivar Marthinusen won a two-day visit to the Laboratory. He poses on the picture surrounded by his CERN's guardian angels: from left to right, Frank Tecker and Georges-Henry Hemelsoet from PS, Tommy Eriksson from AD, Sandrine Sanchez from the Visits Service, Ivar Mathinusen with his parents, Egil Lillestol (CERN/EP), Jens Vigen from the Library, Régine Chareyron from the Visits Service, Richard Jacobsson (CERN/EP) and Sophie Baillard from the Visits Service.

  13. Calvin the preacher: His explanation of the doctrine of predestination in the sermon of 1551 and in the Institutes of 1559.

    Directory of Open Access Journals (Sweden)

    W. H. Neuser

    1998-12-01

    Full Text Available In this study, Calvin 's famous sermon on eternal election of 1551 is dis-cussed and compared to his treatment of the doctrine in his Institutes, 1559. This is a necessary study, never undertaken before, of the correlation between Calvin's pastoral treatment of the Biblical doctrine of predestination and his more didactic-apologetic approach in the Institutes. Here the main argument in the sermon is summarised and, at every point, the corrsponding passage in the Institutes is also discussed and the difference in approach and argument evaluated. In this way a more complete knowledge of Calvin's understanding of this doctrine is gained. To assist the reader, the text of the sermon of 1551 is also published. The final conclusion is that the sermon is a valuable addition to the Institutes. Without it, Calvin's pastoral treatment of the doctrine is ignored when evaluating his exposition on eternal election.

  14. Engineering carbon fixation in E. coli: from heterologous RuBisCO expression to the Calvin-Benson-Bassham cycle.

    Science.gov (United States)

    Antonovsky, Niv; Gleizer, Shmuel; Milo, Ron

    2017-10-01

    Carbon fixation is the gateway of inorganic carbon into the biosphere. Our ability to engineer carbon fixation pathways in living organisms is expected to play a crucial role in the quest towards agricultural and energetic sustainability. Recent successes to introduce non-native carbon fixation pathways into heterotrophic hosts offer novel platforms for manipulating these pathways in genetically malleable organisms. Here, we focus on past efforts and future directions for engineering the dominant carbon fixation pathway in the biosphere, the Calvin-Benson cycle, into the well-known model organism Escherichia coli. We describe how central carbon metabolism of this heterotrophic bacterium can be manipulated to allow directed evolution of carbon fixing enzymes. Finally, we highlight future directions towards synthetic autotrophy. Copyright © 2017 Elsevier Ltd. All rights reserved.

  15. THE WEBER THESIS OF CALVINISM AND CAPITALISM--ITS VARIOUS VERSIONS AND THEIR "FATE" IN SOCIAL SCIENCE.

    Science.gov (United States)

    Zafirovski, Milan

    2016-01-01

    The paper identifies and examines various multiple renditions of the so-called Weber Thesis of an historical association and convergence between ascetic Protestantism, above all Calvinism, and the emergence and development of modern capitalism as an economic spirit and system. Specifically, it detects at least four different versions and formulations or interpretations, thus casting doubt in the common view of the Weber Thesis as a single and monolithic theory or hypothesis. The paper also considers the status of the multiple versions of the Weber Thesis in post-Weberian and contemporary sociology and related disciplines like economics and history. It concludes that the weaker, relaxed renditions of the Weber Thesis have attained a greater success and more endured in contemporary social science than have its stronger, stricter versions. © 2015 Wiley Periodicals, Inc.

  16. Winner-take-all in a phase oscillator system with adaptation.

    Science.gov (United States)

    Burylko, Oleksandr; Kazanovich, Yakov; Borisyuk, Roman

    2018-01-11

    We consider a system of generalized phase oscillators with a central element and radial connections. In contrast to conventional phase oscillators of the Kuramoto type, the dynamic variables in our system include not only the phase of each oscillator but also the natural frequency of the central oscillator, and the connection strengths from the peripheral oscillators to the central oscillator. With appropriate parameter values the system demonstrates winner-take-all behavior in terms of the competition between peripheral oscillators for the synchronization with the central oscillator. Conditions for the winner-take-all regime are derived for stationary and non-stationary types of system dynamics. Bifurcation analysis of the transition from stationary to non-stationary winner-take-all dynamics is presented. A new bifurcation type called a Saddle Node on Invariant Torus (SNIT) bifurcation was observed and is described in detail. Computer simulations of the system allow an optimal choice of parameters for winner-take-all implementation.

  17. Neuronal Networks with NMDARs and Lateral Inhibition Implement Winner-Takes-All

    Directory of Open Access Journals (Sweden)

    Patrick A Shoemaker

    2015-02-01

    Full Text Available A neural circuit that relies on the electrical properties of NMDA synaptic receptors is shown by numerical and theoretical analysis to be capable of realizing the winner-takes-all function, a powerful computational primitive that is often attributed to biological nervous systems. This biophysically-plausible model employs global lateral inhibition in a simple feedback arrangement. As its inputs increase, high-gain and then bi- or multi-stable equilibrium states may be assumed in which there is significant depolarization of a single neuron and hyperpolarization or very weak depolarization of other neurons in the network. The state of the winning neuron conveys analog information about its input. The winner-takes-all characteristic depends on the nonmonotonic current-voltage relation of NMDA receptor ion channels, as well as neural thresholding, and the gain and nature of the inhibitory feedback. Dynamical regimes vary with input strength. Fixed points may become unstable as the network enters a winner-takes-all regime, which can lead to entrained oscillations. Under some conditions, oscillatory behavior can be interpreted as winner-takes-all in nature. Stable winner-takes-all behavior is typically recovered as inputs increase further, but with still larger inputs, the winner-takes-all characteristic is ultimately lost. Network stability may be enhanced by biologically plausible mechanisms.

  18. Unsupervised Feature Learning With Winner-Takes-All Based STDP

    Directory of Open Access Journals (Sweden)

    Paul Ferré

    2018-04-01

    Full Text Available We present a novel strategy for unsupervised feature learning in image applications inspired by the Spike-Timing-Dependent-Plasticity (STDP biological learning rule. We show equivalence between rank order coding Leaky-Integrate-and-Fire neurons and ReLU artificial neurons when applied to non-temporal data. We apply this to images using rank-order coding, which allows us to perform a full network simulation with a single feed-forward pass using GPU hardware. Next we introduce a binary STDP learning rule compatible with training on batches of images. Two mechanisms to stabilize the training are also presented : a Winner-Takes-All (WTA framework which selects the most relevant patches to learn from along the spatial dimensions, and a simple feature-wise normalization as homeostatic process. This learning process allows us to train multi-layer architectures of convolutional sparse features. We apply our method to extract features from the MNIST, ETH80, CIFAR-10, and STL-10 datasets and show that these features are relevant for classification. We finally compare these results with several other state of the art unsupervised learning methods.

  19. Route de Meyrin-CERN: and the winner is...

    CERN Multimedia

    2012-01-01

    Last night, CERN’s engagement with society took an important step forward with the unveiling of the winner of the architectural competition for the Route de Meyrin between CERN’s entrances A and B. The winning entry is a project entitled “Metaphoros”, entered by Studio Bürgi of Ticino.   Metaphoros was selected by a jury, of which I was a member, from an impressive range of proposals from around the world. It will be some time before construction gets underway, but anyone who’d like a forward look at how the gateway to CERN will look from 2014 can visit an exhibition in the Globe opening today and running until 28 January. The exhibition focuses on the winning entry, but also has a place for the runners-up, and for the Cosmic Rings of CERN proposal for buildings and landscaping around the Globe, which, subject to external funding, will merge seamlessly with Metaphoros as the next phase in the redevelopment of CERN’s public sp...

  20. Salivary hormones and anxiety in winners and losers of an international judo competition.

    Science.gov (United States)

    Papacosta, Elena; Nassis, George P; Gleeson, Michael

    2016-01-01

    The purpose of this study was to investigate the responses of salivary hormones and salivary secretory immunoglobulin A (SIgA) and anxiety in winners and losers during an international judo competition. Twenty-three trained, male, national-level judo athletes provided three saliva samples during a competition day: morning, in anticipation of competition after an overnight fast, mid-competition, and post-competition within 15 min post-fight for determination of salivary cortisol, salivary testosterone, salivary testosterone/cortisol ratio, SIgA absolute concentrations, SIgA secretion rate and saliva flow rate. The competitive state anxiety inventory questionnaire was completed by the athletes (n = 12) after the first saliva collection for determination of somatic anxiety, cognitive anxiety and self-confidence. Winners were considered 1-3 ranking place (n = 12) and losers (n = 11) below third place in each weight category. Winners presented higher anticipatory salivary cortisol concentrations (p = 0.03) and a lower mid-competition salivary testosterone/cortisol ratio (p = 0.003) compared with losers with no differences for salivary testosterone. Winners tended to have higher SIgA secretion rates (p = 0.07) and higher saliva flow rates (p = 0.009) at mid-competition. Higher levels of cognitive anxiety (p = 0.02) were observed in the winners, without differences according to the outcome in somatic anxiety and self-confidence. The results suggest that winners experienced higher levels of physiological arousal and better psychological preparedness in the morning, and as the competition progressed, the winners were able to control their stress response better.

  1. Simulated ocean acidification reveals winners and losers in coastal phytoplankton

    Science.gov (United States)

    Alvarez-Fernandez, Santiago; Hornick, Thomas; Stuhr, Annegret; Riebesell, Ulf

    2017-01-01

    The oceans absorb ~25% of the annual anthropogenic CO2 emissions. This causes a shift in the marine carbonate chemistry termed ocean acidification (OA). OA is expected to influence metabolic processes in phytoplankton species but it is unclear how the combination of individual physiological changes alters the structure of entire phytoplankton communities. To investigate this, we deployed ten pelagic mesocosms (volume ~50 m3) for 113 days at the west coast of Sweden and simulated OA (pCO2 = 760 μatm) in five of them while the other five served as controls (380 μatm). We found: (1) Bulk chlorophyll a concentration and 10 out of 16 investigated phytoplankton groups were significantly and mostly positively affected by elevated CO2 concentrations. However, CO2 effects on abundance or biomass were generally subtle and present only during certain succession stages. (2) Some of the CO2-affected phytoplankton groups seemed to respond directly to altered carbonate chemistry (e.g. diatoms) while others (e.g. Synechococcus) were more likely to be indirectly affected through CO2 sensitive competitors or grazers. (3) Picoeukaryotic phytoplankton (0.2–2 μm) showed the clearest and relatively strong positive CO2 responses during several succession stages. We attribute this not only to a CO2 fertilization of their photosynthetic apparatus but also to an increased nutrient competitiveness under acidified (i.e. low pH) conditions. The stimulating influence of high CO2/low pH on picoeukaryote abundance observed in this experiment is strikingly consistent with results from previous studies, suggesting that picoeukaryotes are among the winners in a future ocean. PMID:29190760

  2. Optimizing anaerobic growth rate and fermentation kinetics in Saccharomyces cerevisiae strains expressing Calvin-cycle enzymes for improved ethanol yield.

    Science.gov (United States)

    Papapetridis, Ioannis; Goudriaan, Maaike; Vázquez Vitali, María; de Keijzer, Nikita A; van den Broek, Marcel; van Maris, Antonius J A; Pronk, Jack T

    2018-01-01

    Reduction or elimination of by-product formation is of immediate economic relevance in fermentation processes for industrial bioethanol production with the yeast Saccharomyces cerevisiae . Anaerobic cultures of wild-type S. cerevisiae require formation of glycerol to maintain the intracellular NADH/NAD + balance. Previously, functional expression of the Calvin-cycle enzymes ribulose-1,5-bisphosphate carboxylase (RuBisCO) and phosphoribulokinase (PRK) in S. cerevisiae was shown to enable reoxidation of NADH with CO 2 as electron acceptor. In slow-growing cultures, this engineering strategy strongly decreased the glycerol yield, while increasing the ethanol yield on sugar. The present study explores engineering strategies to improve rates of growth and alcoholic fermentation in yeast strains that functionally express RuBisCO and PRK, while maximizing the positive impact on the ethanol yield. Multi-copy integration of a bacterial-RuBisCO expression cassette was combined with expression of the Escherichia coli GroEL/GroES chaperones and expression of PRK from the anaerobically inducible DAN1 promoter. In anaerobic, glucose-grown bioreactor batch cultures, the resulting S. cerevisiae strain showed a 31% lower glycerol yield and a 31% lower specific growth rate than a non-engineered reference strain. Growth of the engineered strain in anaerobic, glucose-limited chemostat cultures revealed a negative correlation between its specific growth rate and the contribution of the Calvin-cycle enzymes to redox homeostasis. Additional deletion of GPD2 , which encodes an isoenzyme of NAD + -dependent glycerol-3-phosphate dehydrogenase, combined with overexpression of the structural genes for enzymes of the non-oxidative pentose-phosphate pathway, yielded a CO 2 -reducing strain that grew at the same rate as a non-engineered reference strain in anaerobic bioreactor batch cultures, while exhibiting a 86% lower glycerol yield and a 15% higher ethanol yield. The metabolic engineering

  3. Can We Predict the Winner in a Market with Network Effects? Competition in Cryptocurrency Market

    Directory of Open Access Journals (Sweden)

    Neil Gandal

    2016-07-01

    Full Text Available We analyze how network effects affect competition in the nascent cryptocurrency market. We do so by examining early dynamics of exchange rates among different cryptocurrencies. While Bitcoin essentially dominates this market, our data suggest no evidence of a winner-take-all effect early in the market. Indeed, for a relatively long period, a few other cryptocurrencies competing with Bitcoin (the early industry leader appreciated much more quickly than Bitcoin. The data in this period are consistent with the use of cryptocurrencies as financial assets (popularized by Bitcoin, and not consistent with winner-take-all dynamics. Toward the end of our sample, however, things change dramatically. Bitcoin appreciates against the USD, while other currencies depreciate against the USD. The data in this period are consistent with strong network effects and winner-take-all dynamics. This trend continues at the time of writing.

  4. Assessing and identifying transitional losers and winners in the Serbian society

    Directory of Open Access Journals (Sweden)

    Trifunović Vesna

    2012-01-01

    Full Text Available This paper presents ways to assess and evaluate losers and winners in the Serbian transitional society, through several concrete examples. Therefore, the paper is a follow-up of the manuscript published in the previous Bulletin of Institute of ethnography, and fits into the theoretical framework already stated. The main indicator of a variety of assessment regarding losers and winners is found among comments made by visitors of relevant Internet web sites, referring to news about societal problems and issues during the process of post-socialist transformation. These are directly linked with a phenomenon of losing or winning in transition, such as unemployment, poverty, criminal, success, failure, wealth, and power. Hence, news from two internet sites "Blic" i "B92" served as a source, while their visitors ‘commentaries to the particular news served in the analysis. Specific news was used to define a particular problem or issue, and the commentaries were seen as reactions to the news. The commentaries contain readers’ attitudes, assessment of particular issues and discourses overview. These comments were chosen based on whether they refer directly to the problem of losing/winning in transition, and on their diversity regarding assessment of the problem itself. At the same time, posted texts on the mentioned sites were not unbiased, and they can also serve to identify losers and winners of transition. Defining a category of losers or winners in transition is a complex issue of various interpretations and constructions, making thus a discrepancy in attributed meanings among the members of Serbian society. Controversy and contradictions in expressed attitudes about losers and winners, as well as understanding of these categories, could be explained by various aspects and outlooks held. In brief, an existing particular social heteroglossia, assumes many different readings and attitudes regarding the categories, caused by various factors. The

  5. Winners and Losers in the Finfish Trade on Mafia Island: A Value ...

    African Journals Online (AJOL)

    Winners and Losers in the Finfish Trade on Mafia Island: A Value Chain Analysis. 153 further achieved for some actors in the chain by reducing its length. There is growing concern regarding the continued deprivation of the fishing communities and the need to improve their livelihoods and livelihood diversification. The.

  6. Winners of the First 1960 Televised Presidential Debate between Kennedy and Nixon.

    Science.gov (United States)

    Kraus, Sidney

    1996-01-01

    Reviews the events, studies, and comments (from 1960 to the present) regarding the controversial question of who won the first 1960 televised debate between John F. Kennedy and Richard M. Nixon. Supports the view that, for television viewers, Kennedy was the winner, whereas radio listeners gave Nixon the edge. (SR)

  7. The Great Unknown: Daniel Handler Interviews National Book Award-Winner Judy Blundell

    Science.gov (United States)

    Handler, Daniel

    2009-01-01

    This article presents an interview with National Book Award-winner Judy Blundell. For nearly 20 years, Blundell has toiled in anonymity, turning out more than 100 mysteries, romances, and media tie-ins under various pen names, such as Jude Watson. But in mid-November, the writer-for-hire was suddenly shoved into the spotlight. That's when "What I…

  8. "the winners" and "the losers" in a globalized world: the case of Amazon rainforest

    OpenAIRE

    Majewska, N.

    2012-01-01

    The present paper by using the approach of "the winners" and "the losers" both in economy and environment emphasizes the multiple outcomes that can emerge as a result of interaction between the eager will of profit over the need to protect the environment. The case of the "Amazonian rainforest from Brazil" was taken as an illustrative example

  9. ACCE/ACS National Educator and Leader of the Year Winners: AEC Congratulates These Outstanding Educators

    Science.gov (United States)

    Australian Educational Computing, 2012

    2012-01-01

    This article presents the ACCE/ACS National Educator and Leader of the Year winners. Anne Mirtschin is the recipient of the ACCE/ACS 2012 Educator of the Year Award. Mirtschin is an innovative teacher at Hawkesdale P-12 College a small rural school that is isolated culturally and geographically. She uses online tools and technology to create…

  10. Thirty Years After: The Lives of Former Winners of Mathematical Olympiads.

    Science.gov (United States)

    Karp, Alexander

    2002-01-01

    This follow-up study surveyed earlier winners of the St. Petersburg (Russia) mathematical Olympiad in 1991 (n=58) and 2001 (n=30). Findings are detailed concerning respondents' academic degrees, employment, publications, schools attended, and perceived quality of mathematical education. Respondents' views about education were conservative and…

  11. National Academic Award Winners over Time: Their Family Situation, Education and Interpersonal Relations

    Science.gov (United States)

    Sekowski, Andrzej; Siekanska, Malgorzata

    2008-01-01

    The article presents the results of a study focusing on the family situation, education and interpersonal relations of adults (26-35 years old) who in their adolescence (16-19 years old) displayed exceptional giftedness. One group of those surveyed were national academic award winners (90). The control group consisted of 90 people of no…

  12. From Calvin to Spinoza

    DEFF Research Database (Denmark)

    Albertsen, Niels

    2005-01-01

    Max Weber employed the concept of a spirit of capitalism only in the context of the historical emergence of modern capitalism. Following Luc Boltanski and Ève Chiapello this article presents a transformed concept that applies also to established capitalisms. The concept includes justificatory...... orders of worth, the “grammars” of which are articulated by political philosophy. According to Boltanski and Chiapello a New Spirit of Capitalism has emerged since the 1980s. The new spirit is founded on a “project-oriented” order of worth, which, they argue, does not yet have a grammar. Extending...

  13. From Calvin to Spinoza

    DEFF Research Database (Denmark)

    Albertsen, Niels

    2005-01-01

    Max Weber employed the concept of a spirit of capitalism only in the context of the historical emergence of modern capitalism. Following Luc Boltanski and Ève Chiapello this article presents a transformed concept that applies also to established capitalisms. The concept includes justificatory...... their argument, Spinoza is proposed as the grammarian. This implies the paradox that Spinoza, the philosopher of immanence, is turned into a grammarian of a transcendent order of worth. However, this paradox exactly preserves a central ingredient of Weber’s concept: transcendence....

  14. What are the key characteristics of a Christian life? A comparison of the ethics of Calvin to that of Augustine and their relevance today

    Directory of Open Access Journals (Sweden)

    J.H. van Wyk

    2010-07-01

    Full Text Available Augustine and Calvin are two of the greatest (western theologians of all times and it is illuminating and inspiring to investigate what they have to teach as far as Christian life is concerned. Augustine never wrote a work on Christian ethics in the modern sense of the word but from his many writings we can easily deduce what the key characteristics are. He accepted the natural virtues of philosophers (prudence, for- titude, temperance and justice but subordinated them to the “infused virtues” of faith, hope and love. Special attention was also paid to inter alia happiness, humility and truth. Calvin, on the other hand, although following Augustine in many aspects of theology, rejected the virtue ethics of the Greek philosophers and developed a Christological ethics within the broader context of pneumatology. The key characteristics of a Christian life are self-denial, cross-bearing and meditation on the future life – and of course the correct enjoyment of the present life. Although we appreciate much of what the two church fathers have to say, we live in a totally different world context today, facing challenges of far greater proportions, like economical uncertainty, political instability and an immense ecological crisis. Morality is chal- lenged today as never before in world history. Today we have to rethink the relevance of Christian life not only from an individual personal perspective but also in terms of broader social Christian ethics.

  15. An exploration of the idea of ecodomy in Calvin's view of God and the world: Its implications for churches in South Africa today

    Directory of Open Access Journals (Sweden)

    Jerry Pillay

    2015-07-01

    Full Text Available The Faculty of Theology chose as its theme oikodome, which speaks about the fullness of life for all. This article explored this theme by looking at John Calvin�s understanding of God and the world. In this article, working from the premise of the sovereignty of God, the author attempted to show that undergirding Calvin�s theology is the idea of oikodome. The author showed that for Calvin everything in life is connected to God and thus the idea of oikodome is deeply rooted in Calvin�s theology. The author illustrated this by examining significant themes in Calvin�s teachings on the Trinitarian God, creation, humanity and providence, state and church, transformation of society, concern for the poor, and education. The author used this information to show what implications the idea of oikodome has for churches in South Africa today, especially in the context of poverty and struggle. The author calls on churches to embrace the theological foundation explicated by Calvin in their endeavour to work toward the fullness of life for all people.

  16. Pastoral evaluation on the Basotho’s view of sexuality: Revisiting the views on sexuality of Augustine, Thomas Aquinas, Martin Luther and John Calvin

    Directory of Open Access Journals (Sweden)

    David K. Semenya

    2015-03-01

    Full Text Available This article examines the Basotho’s views on sexuality within a theological context as wellas the conflict between Christianity and cultural beliefs. Most Basotho have strong opinions on the subject of sexuality and those views undoubtedly emanate from the Basotho culture,which makes it necessary to evaluate them. The issue of sexuality is always a topic of discussion amongst people and did not go unnoticed by church fathers, like Augustine. Thomas Aquinas also expressed an interest in the topic in the Middle-Ages. Likewise, reformers of the calibre of Martin Luther and John Calvin espoused views on sexuality. Itis clear that the aforementioned theologians made a marked contribution toward shapingthe current views on sexuality, especially amongst theologians of this age and this is thereason for revisiting their views in this article examining the Basotho view on sexuality.In examining Basotho views on sexuality, the writer of this article will then discuss andevaluate the views of Augustine, Aquinas, Luther and Calvin with special reference tosexual intercourse, sexual intercourse within matrimony, extramarital sexual intercourseand also the unmarried state.

  17. Biased Random-Key Genetic Algorithms for the Winner Determination Problem in Combinatorial Auctions.

    Science.gov (United States)

    de Andrade, Carlos Eduardo; Toso, Rodrigo Franco; Resende, Mauricio G C; Miyazawa, Flávio Keidi

    2015-01-01

    In this paper we address the problem of picking a subset of bids in a general combinatorial auction so as to maximize the overall profit using the first-price model. This winner determination problem assumes that a single bidding round is held to determine both the winners and prices to be paid. We introduce six variants of biased random-key genetic algorithms for this problem. Three of them use a novel initialization technique that makes use of solutions of intermediate linear programming relaxations of an exact mixed integer linear programming model as initial chromosomes of the population. An experimental evaluation compares the effectiveness of the proposed algorithms with the standard mixed linear integer programming formulation, a specialized exact algorithm, and the best-performing heuristics proposed for this problem. The proposed algorithms are competitive and offer strong results, mainly for large-scale auctions.

  18. Forecasting a winner for Malaysian Cup 2013 using soccer simulation model

    Science.gov (United States)

    Yusof, Muhammad Mat; Fauzee, Mohd Soffian Omar; Latif, Rozita Abdul

    2014-07-01

    This paper investigates through soccer simulation the calculation of the probability for each team winning Malaysia Cup 2013. Our methodology used here is we predict the outcomes of individual matches and then we simulate the Malaysia Cup 2013 tournament 5000 times. As match outcomes are always a matter of uncertainty, statistical model, in particular a double Poisson model is used to predict the number of goals scored and conceded for each team. Maximum likelihood estimation is use to measure the attacking strength and defensive weakness for each team. Based on our simulation result, LionXII has a higher probability in becoming the winner, followed by Selangor, ATM, JDT and Kelantan. Meanwhile, T-Team, Negeri Sembilan and Felda United have lower probabilities to win Malaysia Cup 2013. In summary, we find that the probability for each team becominga winner is small, indicating that the level of competitive balance in Malaysia Cup 2013 is quite high.

  19. Hierarchical Winner-Take-All Particle Swarm Optimization Social Network for Neural Model Fitting

    Science.gov (United States)

    Coventry, Brandon S.; Parthasarathy, Aravindakshan; Sommer, Alexandra L.; Bartlett, Edward L.

    2016-01-01

    Particle swarm optimization (PSO) has gained widespread use as a general mathematical programming paradigm and seen use in a wide variety of optimization and machine learning problems. In this work, we introduce a new variant on the PSO social network and apply this method to the inverse problem of input parameter selection from recorded auditory neuron tuning curves. The topology of a PSO social network is a major contributor to optimization success. Here we propose a new social network which draws influence from winner-take-all coding found in visual cortical neurons. We show that the winner-take-all network performs exceptionally well on optimization problems with greater than 5 dimensions and runs at a lower iteration count as compared to other PSO topologies. Finally we show that this variant of PSO is able to recreate auditory frequency tuning curves and modulation transfer functions, making it a potentially useful tool for computational neuroscience models. PMID:27726048

  20. Highlights from e-EPS: the 2015 EPS High Energy Physics Prize winners

    CERN Multimedia

    Thomas Lohse, e-EPS News

    2015-01-01

    The EPS High Energy Physics Division announces the winners of its 2015 prizes, which will be awarded at the Europhysics Conference on High-Energy Physics (EPS-HEP 2015), Vienna (Austria) 22−29 July. Many people from CERN were among the winners.   The 2015 High Energy and Particle Physics Prize, for an outstanding contribution to High Energy Physics, is awarded to James D. Bjorken “for his prediction of scaling behaviour in the structure of the proton that led to a new understanding of the b interaction”, and to Guido Altarelli, Yuri L. Dokshitzer, Lev Lipatov, and Giorgio Parisi “for developing a probabilistic field theory framework for the dynamics of quarks and gluons, enabling a quantitative understanding of high-energy collisions involving hadrons”. The 2015 Giuseppe and Vanna Cocconi Prize, for an outstanding contribution to Particle Astrophysics and Cosmology in the past 15 years, is awarded to Francis Halzen “for his visiona...

  1. Ecotoxicological characterisation and ecofriendlier alternative formulations of a commercial herbicide (Winner Top®)

    OpenAIRE

    Queirós, Libânia Sofia Seixas

    2016-01-01

    Tem-se assistido a um uso potencialmente abusivo de produtos fitofarmacêuticos, com consequentes efeitos ambientais. Assim, o desenvolvimento de produtos mais eficazes e amigos do ambiente é um dos grandes desafios da atualidade. Neste contexto, este trabalho teve como principais objetivos: (i) avaliar a toxicidade dos formulantes ou adjuvantes utilizados nas formulações dos produtos comerciais, utilizando um herbicida modelo (Winner Top®), de forma a verificar se a designação destes ingredie...

  2. The result's dynamic of winners of men's open world powerlifting championships

    OpenAIRE

    Kotendzhy, L.; Stetsenko, A.

    2009-01-01

    The research is devoted to the problem of world mens powerlifting development. Performance of the winners of world mens powerlifting championships was analyzed, that enables to extend the notion of the laws of development and prospects of powerlifting. Productivity of world champions in powerlifting among men tends to body height. It testifi es to a permanent state of development of powerlifting. Dynamics of outcomes of world champions can depend on different factors.

  3. Recognizing 21. century citizenship: 1997 federal energy and water management award winners

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-12-31

    Energy is a luxury that no one can afford to waste, and many Federal government agencies are becoming increasingly aware of the importance of using energy wisely. Thoughtful use of energy resources is important, not only to meet agency goals, but because energy efficiency helps improve air quality. Sound facility management offers huge savings that affect the agency`s bottom line, the environment, and workplace quality. Hard work, innovation, and vision are characteristic of those who pursue energy efficiency. That is why the Department of Energy, Federal Energy Management Program (FEMP) is proud to salute the winners of the 1997 Federal Energy and Water Management Award. The 1997 winners represent the kind of 21st century thinking that will help achieve widespread Federal energy efficiency. In one year, the winners, through a combination of public and private partnerships, saved more than $100 million and 9.8 trillion Btu by actively identifying and implementing energy efficiency, water conservation, and renewable energy projects. The contributions of these individuals, small groups, and organizations are presented in this report.

  4. Join the CERN ISEF special award winners | 16 June - 3 p.m.

    CERN Multimedia

    2016-01-01

    Come and join the CERN ISEF special award winners at their lightning talks session on 16 June at 3.00 p.m. in the main auditorium.   The 2016 Intel ISEF CERN special award winners on stage with the selection committee on 17 May 2016 in Phoenix, Arizona, USA. (Picture: Society for Science and the Public) Between 11 and 17 June 2016, the ten finalists of the Intel International Science and Engineering Fair (ISEF) who won the CERN Special Award, will visit CERN to partake in various educational lectures. ISEF is the world's largest international pre-college science competition, with approximately 1,700 high school students from more than 75 countries taking part. They will present their projects in short 5 minutes lightning talks' sessions at the main auditorium on Thursday 16 June at 3 p.m. The award winners would be also very happy to have a chance to interact and discuss with you af...

  5. The conceptualization of winners and losers of transition in popular culture

    Directory of Open Access Journals (Sweden)

    Vesna Trifunović

    2016-02-01

    Full Text Available This paper is about the reconstruction of social presentations (picture, vision of losers and winners of transition based on the products of the popular culture such as the domestic TV series. The given picture was considered in the context of the 1990s, when those TV series were filmed and aired (broadcast, which means that they are typical, primarily, for the period of the so-called first transition. The analysis meant the abstracting one of the dominant themes in both TV series which refers to a certain family of ordinary people, faced with the everyday problems of the time their time, and those problems being mainly existential ones. The identification of the messages about losers and winners of transition, which was being sent through these TV series, was later continued by establishing a formula based on which the mentioned theme (subject was structured, and in the end completed by putting in connection the perceived oppostitions via semiotic square. The conceptualization of losers and winners of transition, which is the result of this paper, in no way implies that this vision of theirs is the only and the dominant one in this society. On the other hand, it certainly exists (existed in the given moment and context and as such it came to surface through domestic TV series as the product of popular culture, through which often widespread and popular attitudes of a society are expressed.

  6. Wingless signaling regulates winner/loser status in Minute cell competition.

    Science.gov (United States)

    Akai, Nanami; Igaki, Tatsushi; Ohsawa, Shizue

    2018-03-01

    Cells heterozygously mutant for a ribosomal protein gene, called Minute/+ mutants, are eliminated from epithelium by cell competition when surrounded by wild-type cells. Whereas several factors that regulate Minute cell competition have been identified, the mechanisms how winner/loser status is determined and thereby triggers cell competition are still elusive. To address this, we established two assay systems for Minute cell competition, namely (i) the CORE (competitive elimination of RpS3-RNAi-expressing cells) system in which RpS3-RNAi-expressing wing pouch cells are eliminated from wild-type wing disc and (ii) the SURE (supercompetition of RpS3-expressing clones in RpS3/+ tissue) system in which RpS3-over-expressing clones generated in RpS3/+ wing disc outcompete surrounding RpS3/+ cells. An ectopic over-expression screen using the CORE system identified Wg signaling as a critical regulator of Minute cell competition. Activation of Wg signaling in loser cells suppressed their elimination, whereas down-regulation of Wg signaling in loser cells enhanced their elimination. Furthermore, using the SURE system, we found that down-regulation of Wg signaling in winner cells suppressed elimination of neighboring losers. Our observations suggest that cellular Wg signaling activity is crucial for determining winner/loser status and thereby triggering Minute cell competition. © 2018 Molecular Biology Society of Japan and John Wiley & Sons Australia, Ltd.

  7. An Organizational Model for Excellence in Healthcare Delivery: Evidence From Winners of the Baldrige Quality Award.

    Science.gov (United States)

    Griffith, John R

    Winners of the Baldrige National Quality Award in healthcare have documented top quartile clinical outcomes and patient satisfaction across a variety of American communities and a full spectrum of care. Their results also show high levels of satisfaction among physicians, nurses, and other workers, as well as effective financial performance. The managerial methods they use-collectively, the Baldrige model-are consistent with organizational theory literature and are found across all winners. The winners have sustained excellence after winning and expanded it by acquisition of other healthcare organizations.The model differs substantially from traditional management approaches in healthcare delivery. It is a comprehensive program that emphasizes a shared focus on excellence, systematically responsive management, evidence-based medicine, multidimensional measures and negotiated goals, improvement of work processes, thorough training, and extensive rewards. The model could be expanded on a much larger scale. Doing so successfully would substantially improve the quality and cost of healthcare, as well as the satisfaction and commitment of care providers and other staff. The opportunity deserves further study and trial by large healthcare delivery systems, insurers, and consulting companies.

  8. Imitating winner or sympathizing loser? Quadratic effects on cooperative behavior in prisoners' dilemma games

    Science.gov (United States)

    Lu, Peng

    2015-10-01

    Cooperation is vital in human societies and therefore is widely investigated in the evolutionary game theory. Varieties of mechanisms have been proposed to overcome temptation and promote cooperation. Existing studies usually believe that agents are rational, but irrationalism such as emotions and feelings matters as well. Winner and loser are defined by their payoffs. In addition to admiring and imitating winners, the mechanism of sympathizing and imitating losers is introduced into the model as an alternative action rule, and each one plays the prisoners' dilemma game with eight neighbors under the influence of both irrationalism and rationalism. Rationalism refers to imitating winner to get highest payoff, and irrationalism means that people sympathize and adopt the actions of losers. As it is widely recognized that temptation reduces cooperation, this study focuses on the effect of sympathy on cooperation within a certain group or society. If it overcomes temptation that leads to defection, sympathy will be a powerful mechanism to promote cooperative behavior. Simulation results indicate that sympathy and temptation shares similar quadratic relationships with cooperation. Both sympathy and temptation undermine cooperation below their thresholds, and they both promote cooperation above their thresholds. Temptation not only reduces cooperation but also promote it as temptation goes beyond the threshold. Although sympathy is a good merit or human nature that is beneficial to society, a crisis or collapse of cooperation is inevitable when the sympathy propensity is relatively smaller. After cooperation reaches a minimal bottom, it then rises increasingly and dramatically, which brings a much brighter future of the society.

  9. Construction of a novel d-lactate producing pathway from dihydroxyacetone phosphate of the Calvin cycle in cyanobacterium, Synechococcus elongatus PCC 7942.

    Science.gov (United States)

    Hirokawa, Yasutaka; Goto, Ryota; Umetani, Yoshitaka; Hanai, Taizo

    2017-07-01

    Using engineered cyanobacteria to produce various chemicals from carbon dioxide is a promising technology for a sustainable future. Lactate is a valuable commodity that can be used for the biodegradable plastic, polylactic acid. Typically, lactate production using engineered cyanobacteria was via the conversion of pyruvate in glycolysis by lactate dehydrogenase. In cyanobacteria, the metabolic flux in the Calvin cycle is higher than that in glycolysis under photoautotrophic conditions. The construction of a novel lactate producing pathway that uses metabolites from the Calvin cycle could potentially increase lactate productivity in cyanobacteria. In order to develop such a novel lactate production pathway, we engineered a cyanobacterium Synechococcus elongatus PCC 7942 strain that produced lactate directly from carbon dioxide using dihydroxyacetone phosphate (DHAP) via methylglyoxal. We confirmed that wild-type strain of S. elongatus PCC 7942 could produce lactate using exogenous methylglyoxal. A methylglyoxal synthase gene, mgsA, from Escherichia coli was introduced into Synechococcus elongates PCC 7942 for conversion of DHAP to methylglyoxal. This engineered strain produced lactate directly from carbon dioxide. Genes encoding intrinsic putative glyoxalase I, II (Synpcc7942_0638, 1403) and the lactate/H + symporter from E. coli (lldP) were additionally introduced to enhance the production. For higher lactate production, it was important to maintain elevated extracellular pH due to the characteristics of lactate exporting system. In this study, the highest lactate titer of 13.7 mM (1.23 g/l) was achieved during a 24-day incubation with the engineered S. elongatus PCC 7942 strain possessing the novel lactate producing pathway. Copyright © 2017 The Society for Biotechnology, Japan. Published by Elsevier B.V. All rights reserved.

  10. Fast block matching algorithm based on the winner-update strategy.

    Science.gov (United States)

    Chen, Y S; Hung, Y P; Fuh, C S

    2001-01-01

    Block matching is a widely used method for stereo vision, visual tracking, and video compression. Many fast algorithms for block matching have been proposed in the past, but most of them do not guarantee that the match found is the globally optimal match in a search range. This paper presents a new fast algorithm based on the winner-update strategy which utilizes an ascending lower bound list of the matching error to determine the temporary winner. Two lower bound lists derived by using partial distance and by using Minkowski's inequality are described. The basic idea of the winner-update strategy is to avoid, at each search position, the costly computation of the matching error when there exists a lower bound larger than the global minimum matching error. The proposed algorithm can significantly speed up the computation of the block matching because: 1) computational cost of the lower bound we use is less than that of the matching error itself; 2) an element in the ascending lower bound list will be calculated only when its preceding element has already been smaller than the minimum matching error computed so far; 3) for many search positions, only the first several lower bounds in the list need to be calculated. Our experiments have shown that, when applying to motion vector estimation for several widely-used test videos, 92% to 98% of operations can be saved while still guaranteeing the global optimality. Moreover, the proposed algorithm can be easily modified either to meet the limited time requirement or to provide an ordered list of best candidate matches. Our source codes of the proposed algorithm are available at http://smart.iis.sinica.edu.tw/html/winup.html.

  11. Age and sex differences in game-related statistics which discriminate winners from losers in elite basketball games

    Directory of Open Access Journals (Sweden)

    Haruhiko Madarame

    2018-02-01

    Full Text Available Abstract AIMS To advance knowledge of long-term development of basketball players, this study investigated age and sex differences in game-related statistics which discriminate winners from losers in World Basketball Championships held after the 2010 rule change. METHODS A total of 935 games from six categories (under-17, under-19 and open age for both men and women were analyzed. All games were classified into three types (balanced, unbalanced and very unbalanced according to point differential by a k-means cluster analysis. A discriminant analysis was performed to identify game-related statistics which discriminate winners from losers in each game type. An absolute value of a structural coefficient (SC equal to or above 0.30 was considered relevant for the discrimination. RESULTS In balanced games, assists discriminated winners from losers in open games (men, |SC| = 0.32; women, |SC| = 0.34, whereas successful free throws did so in under-17 games (men, |SC| = 0.30; women, |SC| = 0.31. Successful 2-point field goals discriminated winners from losers only in women’s games (under-19, |SC| = 0.38; open, |SC| = 0.36. CONCLUSION There were three novel findings in balanced games: 1 successful free throws but not assists discriminated winners from losers in under-17 games; 2 successful 2-point field goals discriminated winners from losers in women’s games but not in men’s games; and 3 discriminating power of successful 3-point field goals was extremely small in women’s games. These results may be related to the new rules for the shot clock and the 3-point distance.

  12. Mechanisms of Winner-Take-All and Group Selection in Neuronal Spiking Networks.

    Science.gov (United States)

    Chen, Yanqing

    2017-01-01

    A major function of central nervous systems is to discriminate different categories or types of sensory input. Neuronal networks accomplish such tasks by learning different sensory maps at several stages of neural hierarchy, such that different neurons fire selectively to reflect different internal or external patterns and states. The exact mechanisms of such map formation processes in the brain are not completely understood. Here we study the mechanism by which a simple recurrent/reentrant neuronal network accomplish group selection and discrimination to different inputs in order to generate sensory maps. We describe the conditions and mechanism of transition from a rhythmic epileptic state (in which all neurons fire synchronized and indiscriminately to any input) to a winner-take-all state in which only a subset of neurons fire for a specific input. We prove an analytic condition under which a stable bump solution and a winner-take-all state can emerge from the local recurrent excitation-inhibition interactions in a three-layer spiking network with distinct excitatory and inhibitory populations, and demonstrate the importance of surround inhibitory connection topology on the stability of dynamic patterns in spiking neural network.

  13. Technical and physical analysis of the 2014 FIFA World Cup Brazil: winners vs. losers.

    Science.gov (United States)

    Rumpf, Michael C; Silva, Joao R; Hertzog, Maxime; Farooq, Abdulaziz; Nassis, George

    2017-10-01

    The purpose of the present study was to investigate the technical and physical performance parameters that distinguish between teams winning and losing matches in the 2014 FIFA World Cup Brazil. Data were derived from the FIFA website and from live-statistics provided during each game of the world cup. Twelve physical (such as total distance covered in meters (TD), TD in distinct locomotor categories: low-intensity running (LIR; 14 km/h)) and 21 technical parameters (total passes, short-, medium- and long-distance passes, total pass completion rate, dangerous attacks, attacking attempts, delivery in penalty area, ball possession, goals, goals from set-pieces, goals per shot on goal, defending saves, shots, shots on goal, shot accuracy, set-pieces, crosses, corners, clearances, yellow cards) were analyzed. Forty-two games in which a winner and consequently a loser were presented after 90 minutes of game time were investigated with independent t-tests. A binary-logistic regression was utilized to investigate whether the significant variables predicted success of the winning teams. The winning teams scored significantly (PTechnical performance related to goal scoring parameters play a decisive role in World Cup games. Furthermore, scoring efficacy from open-play as well as from set-pieces are crucial to win matches in a World Cup tournament. At this level, physical performance was not the factor to discriminate between winners and losers.

  14. Meet the winner artists of Accelerate@CERN Taiwan | 3 February

    CERN Multimedia

    2016-01-01

    The winners of Accelerate@CERN Taiwan are WenChi Su (left) and Pei-Ying Lin (right). Accelerate@CERN is the country-specific, one-month research award for artists who have never been in a science laboratory before. Accelerate@CERN Taiwan, is funded by the Ministry of Culture for Taiwan. From within thirty outstanding applicants, the winners of Accelerate@CERN Taiwan are WenChi Su - dancer and choreographer - and Pei-Ying Lin - digital artist. This is the first opportunity for two talented artists to work and research together on the joint creation of a new dance project which engages with the digital realm and is inspired by the world of particle physics. In the past month they have been exploring CERN together, and now they are working on their project. Meet the artists on Wednesday 3 February at 4:30 p.m. in Restaurant 1. For more information on Accelerate@CERN, see here. Follow the artists blog to know what they have been doing for the past month at CERN.

  15. Winners and losers: analysing post-disaster spatial economic demand shift.

    Science.gov (United States)

    Xiao, Yu; Nilawar, Uttara

    2013-10-01

    Disasters produce winners and losers. This paper evaluates such winners and losers in a spatial context. The hypothesis is that, because of severe damage to the core disaster area and the constraints associated with the cost of transportation, economic demand would shift to the immediate edge of the disaster zone where either minor or no damage is observed. Empirical analysis of growth patterns in counties/parishes in the states of Alabama, Louisiana, and Mississippi in the United States after Hurricane Katrina (August 2005) verified the spatial demand shift hypothesis. The study found that the post-Katrina core disaster area became a 'doughnut hole' of low income and employment growth, surrounded by a ring of high growth counties/parishes on the edge of the hole. The short-run adjustment in growth rates may have altered permanently the spatial distribution of employment and income both at the core and in the areas at the edge. © 2013 The Author(s). Disasters © Overseas Development Institute, 2013.

  16. A reversal of fortunes: climate change 'winners' and 'losers' in Antarctic Peninsula penguins.

    Science.gov (United States)

    Clucas, Gemma V; Dunn, Michael J; Dyke, Gareth; Emslie, Steven D; Naveen, Ron; Polito, Michael J; Pybus, Oliver G; Rogers, Alex D; Hart, Tom

    2014-06-12

    Climate change is a major threat to global biodiversity. Antarctic ecosystems are no exception. Investigating past species responses to climatic events can distinguish natural from anthropogenic impacts. Climate change produces 'winners', species that benefit from these events and 'losers', species that decline or become extinct. Using molecular techniques, we assess the demographic history and population structure of Pygoscelis penguins in the Scotia Arc related to climate warming after the Last Glacial Maximum (LGM). All three pygoscelid penguins responded positively to post-LGM warming by expanding from glacial refugia, with those breeding at higher latitudes expanding most. Northern (Pygoscelis papua papua) and Southern (Pygoscelis papua ellsworthii) gentoo sub-species likely diverged during the LGM. Comparing historical responses with the literature on current trends, we see Southern gentoo penguins are responding to current warming as they did during post-LGM warming, expanding their range southwards. Conversely, Adélie and chinstrap penguins are experiencing a 'reversal of fortunes' as they are now declining in the Antarctic Peninsula, the opposite of their response to post-LGM warming. This suggests current climate warming has decoupled historic population responses in the Antarctic Peninsula, favoring generalist gentoo penguins as climate change 'winners', while Adélie and chinstrap penguins have become climate change 'losers'.

  17. The independent prokaryotic origins of eukaryotic fructose-1, 6-bisphosphatase and sedoheptulose-1, 7-bisphosphatase and the implications of their origins for the evolution of eukaryotic Calvin cycle

    Directory of Open Access Journals (Sweden)

    Jiang Yong-Hai

    2012-10-01

    Full Text Available Abstract Background In the Calvin cycle of eubacteria, the dephosphorylations of both fructose-1, 6-bisphosphate (FBP and sedoheptulose-1, 7-bisphosphate (SBP are catalyzed by the same bifunctional enzyme: fructose-1, 6-bisphosphatase/sedoheptulose-1, 7-bisphosphatase (F/SBPase, while in that of eukaryotic chloroplasts by two distinct enzymes: chloroplastic fructose-1, 6-bisphosphatase (FBPase and sedoheptulose-1, 7-bisphosphatase (SBPase, respectively. It was proposed that these two eukaryotic enzymes arose from the divergence of a common ancestral eubacterial bifunctional F/SBPase of mitochondrial origin. However, no specific affinity between SBPase and eubacterial FBPase or F/SBPase can be observed in the previous phylogenetic analyses, and it is hard to explain why SBPase and/or F/SBPase are/is absent from most extant nonphotosynthetic eukaryotes according to this scenario. Results Domain analysis indicated that eubacterial F/SBPase of two different resources contain distinct domains: proteobacterial F/SBPases contain typical FBPase domain, while cyanobacterial F/SBPases possess FBPase_glpX domain. Therefore, like prokaryotic FBPase, eubacterial F/SBPase can also be divided into two evolutionarily distant classes (Class I and II. Phylogenetic analysis based on a much larger taxonomic sampling than previous work revealed that all eukaryotic SBPase cluster together and form a close sister group to the clade of epsilon-proteobacterial Class I FBPase which are gluconeogenesis-specific enzymes, while all eukaryotic chloroplast FBPase group together with eukaryotic cytosolic FBPase and form another distinct clade which then groups with the Class I FBPase of diverse eubacteria. Motif analysis of these enzymes also supports these phylogenetic correlations. Conclusions There are two evolutionarily distant classes of eubacterial bifunctional F/SBPase. Eukaryotic FBPase and SBPase do not diverge from either of them but have two independent origins

  18. Le discours publicitaire – un discours non-constituant - investigation de l’iconotexte dans la publicité pour le parfum Beauty créé par Calvin Klein -

    Directory of Open Access Journals (Sweden)

    GAFENCU I. Tiberiu

    2012-12-01

    Full Text Available The advertising discourse is a non-constituent discourse. In what follows we shall present an analysis of the advertisement for the Calvin Klein perfume called “Beauty”. Our investigation is focused on the way in which the iconical component and the textual one convey the message of the advertising process by engaging in a reciprocal movement of response, thus completing each other.

  19. Can We Tell Winners and Losers Apart? : Social and Cultural Effects on Facial Expressions of Children and Adults in Games

    NARCIS (Netherlands)

    Mui, Hoi Ching; Goudbeek, Martijn; Swerts, Marc; Freitas-magalhães, A

    2015-01-01

    Can we tell winners and losers apart, on the basis of their facial expressions? In this chapter, we investigate the effects of social and cultural factors on expressions associated with winning and losing in games. Eight-year-olds and adults, who were either Dutch or Chinese, played games alone or

  20. An Evaluation of the Trends of Realism in Caldecott Winner and First Honor Books 1966-1986.

    Science.gov (United States)

    Smith, John A., Jr.; Napier, Georgia

    To determine if there were any consistent tendencies toward the abstract or toward impressionism in the illustration of children's books between the years 1966 and 1986, a study examined the illustrations of Caldecott winners and Honor books. The study replicated John Stewig's study (using his evaluation instrument) of the same topic which covered…

  1. God's servant working for your own good: Notes from modern South Africa on Calvin's commentary on Romans 13: 1-7 and the state

    Directory of Open Access Journals (Sweden)

    P. J. Strauss

    1998-12-01

    Full Text Available This article aims at demonstrating that Calvin's grasp of the message of Romans 13 in its reference to the state is highly relevant for the present South Africa. This includes the belief that the authority of rulers is ordained by God, be it that of a just or an unjust government, and that their right to govern should therefore be respected; that government should maintain a public order of justice and peace within which people can serve God in all spheres of life; that state authorities should use the sword and even the death penalty when needed, and not shy away from this God-given responsibility; that a society in which crime threatens to create chaos needs stronger measures of punishment; and that rebellion against the government or disruption of public life should be resorted to only as an ultimate means and when carefully considered as in the general interest.

  2. Water-splitting-based, sustainable and efficient H2 production in green algae as achieved by substrate limitation of the Calvin-Benson-Bassham cycle.

    Science.gov (United States)

    Nagy, Valéria; Podmaniczki, Anna; Vidal-Meireles, André; Tengölics, Roland; Kovács, László; Rákhely, Gábor; Scoma, Alberto; Tóth, Szilvia Z

    2018-01-01

    Photobiological H 2 production has the potential of becoming a carbon-free renewable energy source, because upon the combustion of H 2 , only water is produced. The [Fe-Fe]-type hydrogenases of green algae are highly active, although extremely O 2 -sensitive. Sulphur deprivation is a common way to induce H 2 production, which, however, relies substantially on organic substrates and imposes a severe stress effect resulting in the degradation of the photosynthetic apparatus. We report on the establishment of an alternative H 2 production method by green algae that is based on a short anaerobic induction, keeping the Calvin-Benson-Bassham cycle inactive by substrate limitation and preserving hydrogenase activity by applying a simple catalyst to remove the evolved O 2 . Cultures remain photosynthetically active for several days, with the electrons feeding the hydrogenases mostly derived from water. The amount of H 2 produced is higher as compared to the sulphur-deprivation procedure and the process is photoautotrophic. Our protocol demonstrates that it is possible to sustainably use algal cells as whole-cell catalysts for H 2 production, which enables industrial application of algal biohydrogen production.

  3. From CO2 to cell: energetic expense of creating biomass using the Calvin-Benson-Bassham and reductive citric acid cycles based on genome data.

    Science.gov (United States)

    Mangiapia, Mary; Scott, Kathleen

    2016-04-01

    The factors driving the dominance of the Calvin-Benson-Bassham cycle (CBB) or reductive citric acid cycle (rCAC) in autotrophic microorganisms in different habitats are debated. Based on costs for synthesizing a few metabolic intermediates, it has been suggested that the CBB poses a disadvantage due to higher metabolic cost. The purpose of this study was to extend this estimate of cost from metabolite synthesis to biomass synthesis. For 12 gammaproteobacteria (CBB) and five epsilonproteobacteria (rCAC), the amount of ATP to synthesize a gram of biomass from CO2 was calculated from genome sequences via metabolic maps. The eleven central carbon metabolites needed to synthesize biomass were all less expensive to synthesize via the rCAC (66%-89% of the ATP needed to synthesize them via CBB). Differences in cell compositions did result in differing demands for metabolites among the organisms, but the differences in cost to synthesize biomass were small among organisms that used a particular pathway (e.g. rCAC), compared to the difference between pathways (rCAC versus CBB). The rCAC autotrophs averaged 0.195 moles ATP per g biomass, while their CBB counterparts averaged 0.238. This is the first in silico estimate of the relative expense of both pathways to generate biomass. © FEMS 2016. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  4. Measuring Excellence: A Closer Look at Malcolm Baldrige National Quality Award Winners in the Manufacturing Category

    Directory of Open Access Journals (Sweden)

    Brian Cazzell

    2009-05-01

    Full Text Available The Malcolm Baldrige National Quality Award is the nation’s highest quality award. The application and review process is outlined in this work. The objective of this study was to examine the five previous winners in the Manufacturing category and to establish a firm conclusion about the award’s impact. The impact of the award was examined in several categories including financial performance, market share, and employee productivity. This study explored the accomplishments of each company and compared the common factors they shared with one another. It was found that all five companies experienced tremendous financial growth on average of 100% in either sales or revenue as a result of their dedication to quality which ultimately led to winning the MBNQA.

  5. GRASP with Hybrid Path Relinking for Bi-Objective Winner Determination in Combinatorial Transportation Auctions

    Directory of Open Access Journals (Sweden)

    Tobias Buer

    2010-10-01

    Full Text Available The procurement of transportation services via large-scale combinatorial auctions involves a couple of complex decisions whose outcome highly influences the performance of the tender process. This paper examines the shipper's task of selecting a subset of the submitted bids which efficiently trades off total procurement cost against expected carrier performance. To solve this bi-objective winner determination problem, we propose a Pareto-based greedy randomized adaptive search procedure (GRASP. As a post-optimizer we use a path relinking procedure which is hybridized with branch-and-bound. Several variants of this algorithm are evaluated by means of artificial test instances which comply with important real-world characteristics. The two best variants prove superior to a previously published Pareto-based evolutionary algorithm.

  6. Using transactional analysis to improve clinical and educational supervision: the Drama and Winner's triangles.

    Science.gov (United States)

    McKimm, Judy; Forrest, Kirsty

    2010-05-01

    The supervisor-trainee relationship is fundamental in ensuring the best continuing education for all trainees. One of the key skills of supervision is being able to communicate effectively; however, this is sometimes difficult. In this article we explore how two transactional analysis models, the Drama and Winner's triangles, can help supervisors work and communicate more effectively with trainees. All supervisors will have had a 'heartsink moment' before meeting a known trainee. The models can be used to explain these situations and what exactly is happening to the communication. The models provide methods of breaking free from these frustrating encounters and moving on with the relationship with your trainee. The models also help us understand the ways in which we can easily be pulled into games and offer insight into our own behaviours and relationships, not only with trainees, but also with patients, carers and colleagues. Real life scenarios are used throughout to explain the models.

  7. Self-deception's adaptive value: effects of positive thinking and the winner effect.

    Science.gov (United States)

    Lopez, Jason Kido; Fuxjager, Matthew J

    2012-03-01

    There is a puzzle about why self-deception, a process that obscures the truth, is so pervasive in human behavior given that tracking the truth seems important for our survival and reproduction. William von Hippel and Robert Trivers argue that, despite appearances, there is good reason to think that self-deception is an adaptation by arguing: (1) self-deception leads to a positive self-perception and (2) a positive self-perception increases an individual's fitness. D.S. Neil Van Leeuwen, however, gives persuasive arguments against both steps. In response, we will defend both propositions, thereby supporting the conclusion that self-deception indeed has adaptive value. The first premise will be bolstered by a survey of the philosophical literature and empirical work on self-deception, whereas the second will be strengthened by empirical research on a behavioral phenomenon known as the winner effect. Copyright © 2011 Elsevier Inc. All rights reserved.

  8. Quality in the 21st century perspectives from ASQ Feigenbaum medal winners

    CERN Document Server

    Saraiva, Pedro

    2016-01-01

    This book is a compilation of perspectives provided by several winners of the ASQ Feigenbaum Medal, which is awarded each year to an individual under the age of 35 who has made a significant contribution to the field of Quality. As such, it serves as a valuable reference book in this area. It is primarily based on the medalists’ vision to "refresh" and "re-think" the quality concepts that have been used over the past century and the future development of the topic. Maximizing readers’ understanding of the ways in which Quality is created, it provides insights from pioneers in this field from around the globe and anticipates how and what Quality will be in the future, as well as how people and organizations can benefit from it today.

  9. The Stock Performance of C. Everett Koop Award Winners Compared With the Standard & Poor's 500 Index

    Science.gov (United States)

    Goetzel, Ron Z.; Fabius, Raymond; Fabius, Dan; Roemer, Enid C.; Thornton, Nicole; Kelly, Rebecca K.; Pelletier, Kenneth R.

    2016-01-01

    Objective: To explore the link between companies investing in the health and well-being programs of their employees and stock market performance. Methods: Stock performance of C. Everett Koop National Health Award winners (n = 26) was measured over time and compared with the average performance of companies comprising the Standard and Poor's (S&P) 500 Index. Results: The Koop Award portfolio outperformed the S&P 500 Index. In the 14-year period tracked (2000–2014), Koop Award winners’ stock values appreciated by 325% compared with the market average appreciation of 105%. Conclusions: This study supports prior and ongoing research demonstrating a higher market valuation—an affirmation of business success by Wall Street investors—of socially responsible companies that invest in the health and well-being of their workers when compared with other publicly traded firms. PMID:26716843

  10. Carbon transitions from either Calvin cycle or transitory starch to heteroglycans as revealed by (14) C-labeling experiments using protoplasts from Arabidopsis.

    Science.gov (United States)

    Malinova, Irina; Steup, Martin; Fettke, Joerg

    2013-09-01

    Plants metabolize transitory starch by precisely coordinated plastidial and cytosolic processes. The latter appear to include the action of water-soluble heteroglycans (SHGin ) whose monosaccharide pattern is similar to that of apoplastic glycans (SHGex ) but, unlike SHGex , SHGin strongly interacts with glucosyl transferases. In this study, we analyzed starch metabolism using mesophyll protoplasts from wild-type plants and two knock-out mutants [deficient in the cytosolic transglucosidase, disproportionating isoenzyme 2 (DPE2) or the plastidial phosphoglucomutase (PGM1)] from Arabidopsis thaliana. Protoplasts prelabeled by photosynthetic (14) CO2 fixation were transferred to an unlabeled medium and were darkened or illuminated. Carbon transitions from the Calvin cycle or from starch to both SHGin and SHGex were analyzed. In illuminated protoplasts, starch turn-over was undetectable but darkened protoplasts continuously degraded starch. During illumination, neither the total (14) C content nor the labeling patterns of the sugar residues of SHGin were significantly altered but both the total amount and the labeling of the constituents of SHGex increased with time. In darkened protoplasts, the (14) C-content of most of the sugar residues of SHGin transiently and strongly increased and then declined. This effect was not observed in any SHGex constituent. In darkened DPE2-deficient protoplasts, none of the SHGin constituents exhibited an essential transient increase in labeling. In contrast, some residues of SHGin from the PGM1 mutant exhibited a transient increase in label but this effect significantly differed from that of the wild type. Two conclusions are reached: first, SHGin and SHGex exert different metabolic functions and second, SHGin is directly involved in starch degradation. © 2013 Scandinavian Plant Physiology Society.

  11. The thrill of victory and the agony of defeat: spontaneous expressions of medal winners of the 2004 Athens Olympic Games.

    Science.gov (United States)

    Matsumoto, David; Willingham, Bob

    2006-09-01

    Facial behaviors of medal winners of the judo competition at the 2004 Athens Olympic Games were coded with P. Ekman and W. V. Friesen's (1978) Facial Affect Coding System (FACS) and interpreted using their Emotion FACS dictionary. Winners' spontaneous expressions were captured immediately when they completed medal matches, when they received their medal from a dignitary, and when they posed on the podium. The 84 athletes who contributed expressions came from 35 countries. The findings strongly supported the notion that expressions occur in relation to emotionally evocative contexts in people of all cultures, that these expressions correspond to the facial expressions of emotion considered to be universal, that expressions provide information that can reliably differentiate the antecedent situations that produced them, and that expressions that occur without inhibition are different than those that occur in social and interactive settings. ((c) 2006 APA, all rights reserved).

  12. Winners, losers, and posers: The effect of power poses on testosterone and risk-taking following competition.

    Science.gov (United States)

    Smith, Kristopher M; Apicella, Coren L

    2017-06-01

    A contribution to a special issue on Hormones and Human Competition. The effect of postural power displays (i.e. power poses) on hormone levels and decision-making has recently been challenged. While Carney et al. (2010) found that holding brief postural displays of power leads to increased testosterone, decreased cortisol and greater economic risk taking, this failed to replicate in a recent high-powered study (Ranehill et al. 2015). It has been put forward that subtle differences in social context may account for the differences in results. Power displays naturally occur within the context of competitions, as do changes in hormones, and researchers have yet to examine the effects of poses within this ecologically relevant context. Using a large sample of 247 male participants, natural winners and losers of a physical competition were randomly assigned to hold a low, neutral or high-power postural display. We found no main effect of pose type on testosterone, cortisol, risk or feelings of power. Winners assigned to a high-power pose had a relative, albeit small, rise in testosterone compared to winners who held neutral or low-power poses. For losers, we found little evidence that high-power poses lead to increased testosterone relative to those holding neutral or low-powered poses. If anything, the reverse was observed - losers had a reduction in testosterone after holding high-power poses. To the extent that changes in testosterone modulate social behaviors adaptively, it is possible that the relative reduction in testosterone observed in losers taking high-powered poses is designed to inhibit further "winner-like" behavior that could result in continued defeat and harm. Still, effects were small, multiple comparisons were made, and the results ran counter to our predictions. We thus treat these conclusions as preliminary. Copyright © 2016 Elsevier Inc. All rights reserved.

  13. Learning and Stabilization of Winner-Take-All DynamicsThrough Interacting Excitatory and Inhibitory Plasticity

    Directory of Open Access Journals (Sweden)

    Jonathan eBinas

    2014-07-01

    Full Text Available Winner-Take-All (WTA networks are recurrently connected populations of excitatory and inhibitory neurons that represent promising candidate microcircuits for implementing cortical computation. WTAs can perform powerful computations, ranging from signal-restoration to state-dependent processing. However, such networks require fine-tuned connectivity parameters to keep the network dynamics within stable operating regimes. In this article, we show how such stability can emerge autonomously through an interaction of biologically plausible plasticity mechanisms that operate simultaneously on all excitatory and inhibitory synapses of the network. A weight-dependent plasticity rule is derived from the triplet spike-timing dependent plasticity model, and its stabilization properties in the mean-field case are analyzed using contraction theory. Our main result provides simple constraints on the plasticity rule parameters, rather than on the weights themselves, which guarantee stable WTA behavior. The plastic network we present is able to adapt to changing input conditions, and to dynamically adjust its gain, therefore exhibiting self-stabilization mechanisms that are crucial for maintaining stable operation in large networks of interconnected subunits. We show how distributed neural assemblies can adjust their parameters for stable WTA function autonomously while respecting anatomical constraints on neural wiring.

  14. Versatile Networks of Simulated Spiking Neurons Displaying Winner-Take-All Behavior

    Directory of Open Access Journals (Sweden)

    Yanqing eChen

    2013-03-01

    Full Text Available We describe simulations of large-scale networks of excitatory and inhibitory spiking neurons that can generate dynamically stable winner-take-all (WTA behavior. The network connectivity is a variant of center-surround architecture that we call center-annular-surround (CAS. In this architecture each neuron is excited by nearby neighbors and inhibited by more distant neighbors in an annular-surround region. The neural units of these networks simulate conductance-based spiking neurons that interact via mechanisms susceptible to both short-term synaptic plasticity and STDP. We show that such CAS networks display robust WTA behavior unlike the center-surround networks and other control architectures that we have studied. We find that a large-scale network of spiking neurons with separate populations of excitatory and inhibitory neurons can give rise to smooth maps of sensory input. In addition, we show that a humanoid Brain-Based-Device (BBD under the control of a spiking WTA neural network can learn to reach to target positions in its visual field, thus demonstrating the acquisition of sensorimotor coordination.

  15. Winners and losers: Ecological and biogeochemical changes in a warming ocean

    Science.gov (United States)

    Dutkiewicz, S.; Scott, J. R.; Follows, M. J.

    2013-04-01

    We employ a marine ecosystem model, with diverse and flexible phytoplankton communities, coupled to an Earth system model of intermediate complexity to explore mechanisms that will alter the biogeography and productivity of phytoplankton populations in a warming world. Simple theoretical frameworks and sensitivity experiments reveal that ecological and biogeochemical changes are driven by a balance between two impacts of a warming climate: higher metabolic rates (the "direct" effect), and changes in the supply of limiting nutrients and altered light environments (the "indirect" effect). On globally integrated productivity, the two effects compensate to a large degree. Regionally, the competition between effects is more complicated; patterns of productivity changes are different between high and low latitudes and are also regulated by how the supply of the limiting nutrient changes. These complex regional patterns are also found in the changes to broad phytoplankton functional groups. On the finer ecological scale of diversity within functional groups, we find that ranges of some phytoplankton types are reduced, while those of others (potentially minor players in the present ocean) expand. Combined change in areal extent of range and in regionally available nutrients leads to global "winners and losers." The model suggests that the strongest and most robust signal of the warming ocean is likely to be the large turnover in local phytoplankton community composition.

  16. Winners of the Skylab Student Program at Marshall Space Flight Center

    Science.gov (United States)

    1972-01-01

    One of the most successful of the Skylab educational efforts was the Skylab Student Project. A nationwide scientific competition was sponsored by the National Science Teachers Association and the National Aeronautics and Space Administration (NASA) in which secondary students were encouraged to submit proposals for experiments to be conducted on Skylan in Earth orbit the following year. After the official announcement of this project, over 4,000 students responded with 3,409 proposals. The winning 25 students, along with their parents and sponsor teachers, visited Marshall Space Flight Center (MSFC), the lead center for Skylab, where they met with scientists and engineers, participated in design reviews for their experiments, and toured MSFC facilities. Of the 25 students, 6 did not see their experiments conducted on Skylab because the experiments were not compatible with Skylab hardware and timelines. Of the 19 remaining, 11 experiments required the manufacture of additional equipment. This photograph is a group shot of the 25 winners, parents, and sponsors when they met for the first time on the steps of Building 4200 at MSFC in the Spring of 1972.

  17. Selective positive-negative feedback produces the winner-take-all competition in recurrent neural networks.

    Science.gov (United States)

    Li, Shuai; Liu, Bo; Li, Yangming

    2013-02-01

    The winner-take-all (WTA) competition is widely observed in both inanimate and biological media and society. Many mathematical models are proposed to describe the phenomena discovered in different fields. These models are capable of demonstrating the WTA competition. However, they are often very complicated due to the compromise with experimental realities in the particular fields; it is often difficult to explain the underlying mechanism of such a competition from the perspective of feedback based on those sophisticate models. In this paper, we make steps in that direction and present a simple model, which produces the WTA competition by taking advantage of selective positive-negative feedback through the interaction of neurons via p-norm. Compared to existing models, this model has an explicit explanation of the competition mechanism. The ultimate convergence behavior of this model is proven analytically. The convergence rate is discussed and simulations are conducted in both static and dynamic competition scenarios. Both theoretical and numerical results validate the effectiveness of the dynamic equation in describing the nonlinear phenomena of WTA competition.

  18. STDP Installs in Winner-Take-All Circuits an Online Approximation to Hidden Markov Model Learning

    Science.gov (United States)

    Kappel, David; Nessler, Bernhard; Maass, Wolfgang

    2014-01-01

    In order to cross a street without being run over, we need to be able to extract very fast hidden causes of dynamically changing multi-modal sensory stimuli, and to predict their future evolution. We show here that a generic cortical microcircuit motif, pyramidal cells with lateral excitation and inhibition, provides the basis for this difficult but all-important information processing capability. This capability emerges in the presence of noise automatically through effects of STDP on connections between pyramidal cells in Winner-Take-All circuits with lateral excitation. In fact, one can show that these motifs endow cortical microcircuits with functional properties of a hidden Markov model, a generic model for solving such tasks through probabilistic inference. Whereas in engineering applications this model is adapted to specific tasks through offline learning, we show here that a major portion of the functionality of hidden Markov models arises already from online applications of STDP, without any supervision or rewards. We demonstrate the emergent computing capabilities of the model through several computer simulations. The full power of hidden Markov model learning can be attained through reward-gated STDP. This is due to the fact that these mechanisms enable a rejection sampling approximation to theoretically optimal learning. We investigate the possible performance gain that can be achieved with this more accurate learning method for an artificial grammar task. PMID:24675787

  19. Winners and losers of national and global efforts to reconcile agricultural intensification and biodiversity conservation.

    Science.gov (United States)

    Egli, Lukas; Meyer, Carsten; Scherber, Christoph; Kreft, Holger; Tscharntke, Teja

    2018-05-01

    Closing yield gaps within existing croplands, and thereby avoiding further habitat conversions, is a prominently and controversially discussed strategy to meet the rising demand for agricultural products, while minimizing biodiversity impacts. The agricultural intensification associated with such a strategy poses additional threats to biodiversity within agricultural landscapes. The uneven spatial distribution of both yield gaps and biodiversity provides opportunities for reconciling agricultural intensification and biodiversity conservation through spatially optimized intensification. Here, we integrate distribution and habitat information for almost 20,000 vertebrate species with land-cover and land-use datasets. We estimate that projected agricultural intensification between 2000 and 2040 would reduce the global biodiversity value of agricultural lands by 11%, relative to 2000. Contrasting these projections with spatial land-use optimization scenarios reveals that 88% of projected biodiversity loss could be avoided through globally coordinated land-use planning, implying huge efficiency gains through international cooperation. However, global-scale optimization also implies a highly uneven distribution of costs and benefits, resulting in distinct "winners and losers" in terms of national economic development, food security, food sovereignty or conservation. Given conflicting national interests and lacking effective governance mechanisms to guarantee equitable compensation of losers, multinational land-use optimization seems politically unlikely. In turn, 61% of projected biodiversity loss could be avoided through nationally focused optimization, and 33% through optimization within just 10 countries. Targeted efforts to improve the capacity for integrated land-use planning for sustainable intensification especially in these countries, including the strengthening of institutions that can arbitrate subnational land-use conflicts, may offer an effective, yet

  20. Ernest Orlando Lawrence Awards Ceremony for 2011 Award Winners (Presentations, including remarks by Energy Secretary, Dr. Steven Chu)

    International Nuclear Information System (INIS)

    Chu, Steven

    2012-01-01

    The winners for 2011 of the Department of Energy's Ernest Orlando Lawrence Award were recognized in a ceremony held May 21, 2012. Dr. Steven Chu and others spoke of the importance of the accomplishments and the prestigious history of the award. The recipients of the Ernest Orlando Lawrence Award for 2011 are: Riccardo Betti (University of Rochester); Paul C. Canfield (Ames Laboratory); Mark B. Chadwick (Los Alamos National Laboratory); David E. Chavez (Los Alamos National Laboratory); Amit Goyal (Oak Ridge National Laboratory); Thomas P. Guilderson (Lawrence Livermore National Laboratory); Lois Curfman McInnes (Argonne National Laboratory); Bernard Matthew Poelker (Thomas Jeffereson National Accelerator Facility); and Barry F. Smith (Argonne National Laboratory).

  1. A novel recurrent neural network with one neuron and finite-time convergence for k-winners-take-all operation.

    Science.gov (United States)

    Liu, Qingshan; Dang, Chuangyin; Cao, Jinde

    2010-07-01

    In this paper, based on a one-neuron recurrent neural network, a novel k-winners-take-all ( k -WTA) network is proposed. Finite time convergence of the proposed neural network is proved using the Lyapunov method. The k-WTA operation is first converted equivalently into a linear programming problem. Then, a one-neuron recurrent neural network is proposed to get the kth or (k+1)th largest inputs of the k-WTA problem. Furthermore, a k-WTA network is designed based on the proposed neural network to perform the k-WTA operation. Compared with the existing k-WTA networks, the proposed network has simple structure and finite time convergence. In addition, simulation results on numerical examples show the effectiveness and performance of the proposed k-WTA network.

  2. David Bowie and the Art of Slow Innovation: A Fast-Second Winner Strategy for Biotechnology and Precision Medicine Global Development.

    Science.gov (United States)

    Özdemir, Vural; Patrinos, George P

    2017-11-01

    Original ideas and innovation cannot always be ordered like a courier service and delivered fresh to our desk at 9 am. Yet, most creativity-based organizations, careers, and professions, science and biotechnology innovation included, emphasize the speed as the prevailing ideology. But a narrow focus on speed has several and overlooked shortcomings. For example, it does not offer the opportunity to draw from, and stitch together disparate concepts and practices for truly disruptive innovation. Preventing false starts, learning from others' or our own mistakes, and customizing innovations for local community needs are difficult in a speed-hungry innovation ecosystem. We introduce a new strategy, the Fast-Second Winner, specifically in relation to global development of biotechnologies and precision medicine. This à la carte global development strategy envisions a midstream entry into the innovation ecosystem. Moreover, we draw from the works of the late David Bowie who defied rigid classifications as an artist and prolific innovator, and introduce the concept and practice of slow innovation that bodes well with the Fast-Second Winner strategy. A type of slow innovation, the Fast-Second Winner is actually fast and sustainable in the long term, and efficient by reducing false starts in new precision medicine application contexts and geographies, learning from other innovators' failures, and shaping innovations for the local community needs. The establishment of Centers for Fast-Second Innovation (CFSIs), and their funding, for example, by crowdfunding and other innovative mechanisms, could be timely for omics and precision medicine global development. If precision medicine is about tailoring drug treatments and various health interventions to individuals, we suggest to start from tailoring new ideas, and focus not only on how much we innovate but also what and how we innovate. In principle, the Fast-Second Winner can be applied to omics and other biotechnology

  3. A little helps a lot The overall winners of this year's Nursing Standard Nurse of the Year awards have enhanced the lives of hundreds of African children.

    Science.gov (United States)

    Moore, Alison

    2003-11-05

    This year's overall Nurse 2003 award is unusual in that there are two winners, Clare McKenzie and Pauline Stratton. Sadly Ms Stratton receives the award posthumously as she died earlier this year in an accident while visiting the award-winning project in Malawi. The nurses, from the North Cumbria Acute Hospitals NHS Trust, won the Robert Tiffany International award and overall prize for their collaboration with Malawian nurses.

  4. Statistical correction of the Winner's Curse explains replication variability in quantitative trait genome-wide association studies.

    Directory of Open Access Journals (Sweden)

    Cameron Palmer

    2017-07-01

    Full Text Available Genome-wide association studies (GWAS have identified hundreds of SNPs responsible for variation in human quantitative traits. However, genome-wide-significant associations often fail to replicate across independent cohorts, in apparent inconsistency with their apparent strong effects in discovery cohorts. This limited success of replication raises pervasive questions about the utility of the GWAS field. We identify all 332 studies of quantitative traits from the NHGRI-EBI GWAS Database with attempted replication. We find that the majority of studies provide insufficient data to evaluate replication rates. The remaining papers replicate significantly worse than expected (p < 10-14, even when adjusting for regression-to-the-mean of effect size between discovery- and replication-cohorts termed the Winner's Curse (p < 10-16. We show this is due in part to misreporting replication cohort-size as a maximum number, rather than per-locus one. In 39 studies accurately reporting per-locus cohort-size for attempted replication of 707 loci in samples with similar ancestry, replication rate matched expectation (predicted 458, observed 457, p = 0.94. In contrast, ancestry differences between replication and discovery (13 studies, 385 loci cause the most highly-powered decile of loci to replicate worse than expected, due to difference in linkage disequilibrium.

  5. Fine-scale ecological and economic assessment of climate change on olive in the Mediterranean Basin reveals winners and losers

    Science.gov (United States)

    Ponti, Luigi; Gutierrez, Andrew Paul; Ruti, Paolo Michele; Dell’Aquila, Alessandro

    2014-01-01

    The Mediterranean Basin is a climate and biodiversity hot spot, and climate change threatens agro-ecosystems such as olive, an ancient drought-tolerant crop of considerable ecological and socioeconomic importance. Climate change will impact the interactions of olive and the obligate olive fruit fly (Bactrocera oleae), and alter the economics of olive culture across the Basin. We estimate the effects of climate change on the dynamics and interaction of olive and the fly using physiologically based demographic models in a geographic information system context as driven by daily climate change scenario weather. A regional climate model that includes fine-scale representation of the effects of topography and the influence of the Mediterranean Sea on regional climate was used to scale the global climate data. The system model for olive/olive fly was used as the production function in our economic analysis, replacing the commonly used production-damage control function. Climate warming will affect olive yield and fly infestation levels across the Basin, resulting in economic winners and losers at the local and regional scales. At the local scale, profitability of small olive farms in many marginal areas of Europe and elsewhere in the Basin will decrease, leading to increased abandonment. These marginal farms are critical to conserving soil, maintaining biodiversity, and reducing fire risk in these areas. Our fine-scale bioeconomic approach provides a realistic prototype for assessing climate change impacts in other Mediterranean agro-ecosystems facing extant and new invasive pests. PMID:24706833

  6. Fine-scale ecological and economic assessment of climate change on olive in the Mediterranean Basin reveals winners and losers.

    Science.gov (United States)

    Ponti, Luigi; Gutierrez, Andrew Paul; Ruti, Paolo Michele; Dell'Aquila, Alessandro

    2014-04-15

    The Mediterranean Basin is a climate and biodiversity hot spot, and climate change threatens agro-ecosystems such as olive, an ancient drought-tolerant crop of considerable ecological and socioeconomic importance. Climate change will impact the interactions of olive and the obligate olive fruit fly (Bactrocera oleae), and alter the economics of olive culture across the Basin. We estimate the effects of climate change on the dynamics and interaction of olive and the fly using physiologically based demographic models in a geographic information system context as driven by daily climate change scenario weather. A regional climate model that includes fine-scale representation of the effects of topography and the influence of the Mediterranean Sea on regional climate was used to scale the global climate data. The system model for olive/olive fly was used as the production function in our economic analysis, replacing the commonly used production-damage control function. Climate warming will affect olive yield and fly infestation levels across the Basin, resulting in economic winners and losers at the local and regional scales. At the local scale, profitability of small olive farms in many marginal areas of Europe and elsewhere in the Basin will decrease, leading to increased abandonment. These marginal farms are critical to conserving soil, maintaining biodiversity, and reducing fire risk in these areas. Our fine-scale bioeconomic approach provides a realistic prototype for assessing climate change impacts in other Mediterranean agro-ecosystems facing extant and new invasive pests.

  7. Climate change winners: receding ice fields facilitate colony expansion and altered dynamics in an Adélie penguin metapopulation.

    Science.gov (United States)

    LaRue, Michelle A; Ainley, David G; Swanson, Matt; Dugger, Katie M; Lyver, Phil O'B; Barton, Kerry; Ballard, Grant

    2013-01-01

    There will be winners and losers as climate change alters the habitats of polar organisms. For an Adélie penguin (Pygoscelis adeliae) colony on Beaufort Island (Beaufort), part of a cluster of colonies in the southern Ross Sea, we report a recent population increase in response to increased nesting habitat as glaciers have receded. Emigration rates of birds banded as chicks on Beaufort to colonies on nearby Ross Island decreased after 2005 as available habitat on Beaufort increased, leading to altered dynamics of the metapopulation. Using aerial photography beginning in 1958 and modern satellite imagery, we measured change in area of available nesting habitat and population size of the Beaufort colony. Population size varied with available habitat, and both increased rapidly since the 1990s. In accord with glacial retreat, summer temperatures at nearby McMurdo Station increased by ~0.50 °C per decade since the mid-1980s. Although the Ross Sea is likely to be the last ocean with an intact ecosystem, the recent retreat of ice fields at Beaufort that resulted in increased breeding habitat exemplifies a process that has been underway in the Ross Sea during the entire Holocene. Furthermore, our results are in line with predictions that major ice shelves and glaciers will retreat rapidly elsewhere in the Antarctic, potentially leading to increased breeding habitat for Adélie penguins. Results further indicated that satellite imagery may be used to estimate large changes in Adélie penguin populations, facilitating our understanding of metapopulation dynamics and environmental factors that influence regional populations.

  8. Climate change winners: receding ice fields facilitate colony expansion and altered dynamics in an Adélie penguin metapopulation.

    Directory of Open Access Journals (Sweden)

    Michelle A LaRue

    Full Text Available There will be winners and losers as climate change alters the habitats of polar organisms. For an Adélie penguin (Pygoscelis adeliae colony on Beaufort Island (Beaufort, part of a cluster of colonies in the southern Ross Sea, we report a recent population increase in response to increased nesting habitat as glaciers have receded. Emigration rates of birds banded as chicks on Beaufort to colonies on nearby Ross Island decreased after 2005 as available habitat on Beaufort increased, leading to altered dynamics of the metapopulation. Using aerial photography beginning in 1958 and modern satellite imagery, we measured change in area of available nesting habitat and population size of the Beaufort colony. Population size varied with available habitat, and both increased rapidly since the 1990s. In accord with glacial retreat, summer temperatures at nearby McMurdo Station increased by ~0.50 °C per decade since the mid-1980s. Although the Ross Sea is likely to be the last ocean with an intact ecosystem, the recent retreat of ice fields at Beaufort that resulted in increased breeding habitat exemplifies a process that has been underway in the Ross Sea during the entire Holocene. Furthermore, our results are in line with predictions that major ice shelves and glaciers will retreat rapidly elsewhere in the Antarctic, potentially leading to increased breeding habitat for Adélie penguins. Results further indicated that satellite imagery may be used to estimate large changes in Adélie penguin populations, facilitating our understanding of metapopulation dynamics and environmental factors that influence regional populations.

  9. Deep sleep after social stress: NREM sleep slow-wave activity is enhanced in both winners and losers of a conflict.

    Science.gov (United States)

    Kamphuis, Jeanine; Lancel, Marike; Koolhaas, Jaap M; Meerlo, Peter

    2015-07-01

    Sleep is considered to be a recovery process of prior wakefulness. Not only duration of the waking period affects sleep architecture and sleep EEG, the quality of wakefulness is also highly important. Studies in rats have shown that social defeat stress, in which experimental animals are attacked and defeated by a dominant conspecific, is followed by an acute increase in NREM sleep EEG slow wave activity (SWA). However, it is not known whether this effect is specific for the stress of social defeat or a result of the conflict per se. In the present experiment, we examined how sleep is affected in both the winners and losers of a social conflict. Sleep-wake patterns and sleep EEG were recorded in male wild-type Groningen rats that were subjected to 1h of social conflict in the middle of the light phase. All animals were confronted with a conspecific of similar aggression level and the conflict took place in a neutral arena where both individuals had an equal chance to either win or lose the conflict. NREM sleep SWA was significantly increased after the social conflict compared to baseline values and a gentle stimulation control condition. REM sleep was significantly suppressed in the first hours after the conflict. Winners and losers did not differ significantly in NREM sleep time, NREM sleep SWA and REM sleep time immediately after the conflict. Losers tended to have slightly more NREM sleep later in the recovery period. This study shows that in rats a social conflict with an unpredictable outcome has quantitatively and qualitatively largely similar acute effects on subsequent sleep in winners and losers. Copyright © 2015 Elsevier Inc. All rights reserved.

  10. Winners and losers in flexible labor markets: the fate of women with chronic illness in contrasting policy environments--Sweden and Britain

    DEFF Research Database (Denmark)

    Burström, Bo; Holland, Paula; Diderichsen, Finn

    2003-01-01

    This study compares employment rates among men and women with and without chronic illness in the contrasting policy environments of Britain and Sweden, through analysis of household surveys for 1979-1995. Professional and managerial groups were winners in both countries, including during recession...... unskilled manual workers in Britain. British women with a chronic illness in the 1990s had less than half the employment rates of healthy women. Such social inequalities were much smaller and less consistent in Sweden, where the impact of illness was softened for all social groups. In Britain, workless men...

  11. Project winners - Ademe

    International Nuclear Information System (INIS)

    2015-01-01

    The French agency of environment and energy management (Ademe) is the operator in charge of innovation for accelerating the ecological and environmental transition. A credit of 3.3 billion euros is allocated to this goal in the framework of forward-looking investment. This budget aims at financing innovative projects of any size with the objective of developing tomorrow's industries. The projects cover the following topics: 1 - carbon-free energies and green chemistry: renewable energy sources (marine, solar, wind and geothermal energies), green chemistry and energy challenges (bio-resources, buildings, energy storage, hydrogen, CO 2 capture, storage and valorization, industry and agriculture), 2 - smart grids, 3 - circular economy (wastes and industrial ecology, sites and soils cleansing, water and biodiversity), 4 - future vehicles: road vehicle (mobility and logistics, electric-powered vehicles and charging facilities, hybrid and thermal engines, vehicles lightering, heavy-duty vehicles), rail and maritime transport. This document presents the financing system, a report of the previous investment campaign (2014), and the list of retained projects for the 2015 investment program

  12. Agribusiness Career Exploration Winner

    Science.gov (United States)

    Gutshall, Bill

    1976-01-01

    Describes the planning, development, status, and instructional materials used in a career awaremess program in agribusiness in Chillicothe, Missouri. The four classes in the program and the results of an appraisal are also described. (HD)

  13. Winner Take All

    DEFF Research Database (Denmark)

    Giacomin, Valeria

    focusing on collaboration across distant locations, to the dynamics of competition. The analysis concludes that: (i) clusters interact and advance through the exchange of knowledge on a shared institutional platform; (ii) competition emerges when players from one location increase their influence over...... the institutional platform to gain control over knowledge generation and transmission; and (iii) the comparative evaluation of business environments and their political risk complement location specificity in assessing cluster competitiveness.......Historically, agricultural crops have been transferred from their native locations to climatically similar ones. In the case of palm oil, the new location (Southeast Asia) outcompeted the native one (West Africa), thanks to a superior cluster organizational structure inherited from rubber...

  14. Be a Winner!

    Science.gov (United States)

    Rudolph, Marty

    1991-01-01

    Describes a step-by-step process for writing a winning application for the U.S. Department of Education Elementary (or Secondary) School Recognition Program. Underscores the importance of faculty involvement. Explains the application process, covering brainstorming, administrative questions, the first and final drafts, and use of various readers.…

  15. The Unintended Consequences of Technological Change: Winners and Losers from GM Technologies and the Policy Response in the Organic Food Market

    Directory of Open Access Journals (Sweden)

    Stuart Smyth

    2015-06-01

    Full Text Available It is often said that innovations create winners and losers. All innovations are somewhat disruptive, but some have more distributed effects. We have a sense of who the winners are and how much they gain. Yet, how much do losers actually lose? Organic farmers frequently like to publicly announce that they are the losers following the commercialization of genetically modified (GM crops, yet consumers in search of non-GM products have helped increase demand for organic products, something that would not have occurred in the absence of GM crops. Are organic farmers really losers? This article lays out the argument that were it not for the commercialization of GM crop varieties in the mid-1990s, organic production and food sectors would not be at the level they enjoy today. That is, the commercialization of GM crops has made the organic industry better off than had GM crops not been commercialized. Theoretical modelling of the organic benefits is complemented by supportive market data. The article concludes that in spite of numerous vocal offerings about the adverse impacts suffered by the organic industry due to GM crop production, the organic industry has gained significantly from that which they vociferously criticize.

  16. Differences in certain features of the basketball game of players in the final game, against the criteria: The winner/loser

    Directory of Open Access Journals (Sweden)

    Rubin Pavle

    2013-01-01

    Full Text Available This paper focuses on the characteristics of the game (applied technical and tactical activity for attack realisation, shooting performance, position of players in team, the segment of the field where the ball is received and where the shot is made from in the final matches of top three club competitions. The aim of this study was to determine whether there are differences in observed characteristics of the basketball game between teams separated by the winner/loser criteria. The sample consisted of all matches of the final games of three league competitions (American professional (NBA league, the Euro-league and the Serbian Super-league played in the season 2011/12. By applying multivariate statistical procedures in the monitored segment application of technical and tactical activities of players, it was observed that the winning team, unlike the defeated team, significantly featured a technical - tactical element of shooting, while in the defeated teams (as opposed to the winners elements of action were dominant: dribbling, penetration, shot and dribbling, jump stop, fake, shot. Higher percentage of using only shooting (without the requirement for other elements of attack used to create an opportunity for the eventual shot realization can point primarily to the successful organization of the attacks (in this case - the winning team. As for the position of players in the team, with the teams that won in the monitored matches, statistically significant was the dominance of the forwards in relation to the defeated teams, which featured more centers in the offense attempts.

  17. CALVIN'S SUDDEN CONVERSION (SUBITA CONVERSIO) AND ...

    African Journals Online (AJOL)

    product of a gradual recognition and human decision, but an event of a decisive regen- eration, resulting in true and .... Therefore, in a word, I interpret repentance as regeneration, whose sole end is to restore in us the .... by the Word.26 God, by a sudden conversion, subdued and brought his mind to a teachable frame.

  18. Calvin and the confessions of the Reformation

    African Journals Online (AJOL)

    2014-04-29

    -. Nuremberg, Germany. He is participating as research fellow of Prof. Dr Johan. Buitendag, Dean of the. Faculty of Theology of the. University of Pretoria, South. Africa. This article represents a reworked version of a.

  19. 9th Annual Webby Awards(R) Unveil Best Sites Of The Year; Former Vice President Al Gore, Webby Winners to be Honored at June 6th Ceremony in New York

    CERN Multimedia

    2005-01-01

    Winners of the Webby Awards, selected by the Academy, were revealed today in over 60 countries - from popular favorites like Community, Fashion, Film, and Politics to new categories making their debut this year, such as Blog, Beauty, Real Estate, Retail, and Social Networking (1/2 page)

  20. High Temperature Superconductors: From Delivery to Applications (Presentation from 2011 Ernest Orlando Lawrence Award-winner, Dr. Amit Goyal, and including introduction by Energy Secretary, Dr. Steven Chu)

    International Nuclear Information System (INIS)

    Goyal, Amit

    2012-01-01

    Dr. Amit Goyal, a high temperature superconductivity (HTS) researcher at Oak Ridge National Laboratory, was named a 2011 winner of the Department of Energy's Ernest Orlando Lawrence Award honoring U.S. scientists and engineers for exceptional contributions in research and development supporting DOE and its mission. Winner of the award in the inaugural category of Energy Science and Innovation, Dr. Goyal was cited for his work in 'pioneering research and transformative contributions to the field of applied high temperature superconductivity, including fundamental materials science advances and technical innovations enabling large-scale applications of these novel materials.' Following his basic research in grain-to-grain supercurrent transport, Dr. Goyal focused his energy in transitioning this fundamental understanding into cutting-edge technologies. Under OE sponsorship, Dr. Goyal co-invented the Rolling Assisted Bi-Axially Textured Substrate technology (RABiTS) that is used as a substrate for second generation HTS wires. OE support also led to the invention of Structural Single Crystal Faceted Fiber Substrate (SSIFFS) and the 3-D Self Assembly of Nanodot Columns. These inventions and associated R and D resulted in 7 R and D 100 Awards including the 2010 R and D Magazine's Innovator of the Year Award, 3 Federal Laboratory Consortium Excellence in Technology Transfer National Awards, a DOE Energy100 Award and many others. As a world authority on HTS materials, Dr. Goyal has presented OE-sponsored results in more than 150 invited talks, co-authored more than 350 papers and is a fellow of 7 professional societies.

  1. Human behaviours associated with dominance in elite amateur boxing bouts: A comparison of winners and losers under the Ten Point Must System

    Science.gov (United States)

    Humberstone, Clare E.; Iredale, K. Fiona; Martin, David T.; Blazevich, Anthony J.

    2017-01-01

    Humans commonly ascertain physical dominance through non-lethal fighting by participating in combat sports. However, the behaviours that achieve fight dominance are not fully understood. Amateur boxing competition, which is judged using the subjective “Ten Point Must-System”, provides insight into fight dominance behaviours. Notational analysis was performed on 26 elite male competitors in a national boxing championship. Behavioural (guard-drop time; movement style [stepping/bouncing time]; clinch-time; interaction-time) and technical (total punches; punches landed [%Hit]; air punches [%Air]; defence) measures were recorded. Participants reported effort required (0–100%) and perceived effect of fatigue on their own performance (5-point Likert scale) following bouts. Differences between winners and losers, and changes across the duration of the bout were examined. Winners punched more accurately than losers (greater %Hit [33% vs. 23%] and lower %Air [17% vs. 27%]) but total punches, defence and interaction-time were similar. From rounds 1–2, clinch-time and guard drops increased whilst bouncing decreased. Perceived effect of fatigue increased throughout the bout while perceived effort increased only from rounds 2–3. %Hit and movement index together in regression analysis correctly classified 85% of bout outcomes, indicating that judges (subjectively) chose winning (dominant) boxers according to punch accuracy and style, rather than assertiveness (more punches thrown). Boxers appear to use tactical strategies throughout the bout to pace their effort and minimise fatigue (increased guard drops, reduced bouncing), but these did not influence perceived dominance or bout outcome. These results show that judges use several performance indicators not including the total number of successful punches thrown to assess fight dominance and superiority between fighters. These results provide valuable information as to how experienced fight observers subjectively rate

  2. A Kiss Lajos-díj 2016. évi nyertese: dr. Póczos Rita [Winner of the 2016 Lajos Kiss Prize: Dr Rita Póczos

    Directory of Open Access Journals (Sweden)

    Hoffmann, István

    2016-12-01

    Full Text Available The Lajos Kiss Prize, awarded every two or three years since 2006, is considered to be a highly prestigious award for young onomasticians. The 2016 winner of the prize is Dr Rita Póczos, senior lecturer at the Department of Hungarian Linguistics of the University of Debrecen. She was given this award for her contribution to Hungarian Historical Onomastics, especially for her research on place names.

  3. A Kiss Lajos-díj 2014. évi nyertese: dr. Slíz Mariann [The 2014 winner of Lajos Kiss Prize: Dr Mariann Slíz

    Directory of Open Access Journals (Sweden)

    Hoffmann, István

    2014-12-01

    Full Text Available The Lajos Kiss Prize, awarded every two or three years since 2006, is considered to be a highly prestigious award for young onomasticians. The 2014 winner of the prize is Dr Mariann Slíz, senior lecturer at the Department of Hungarian Linguistics and Finno-Ugric Studies of Eötvös Loránd University, Budapest. She earned this award for her contribution to Hungarian Onomastics, especially in research on personal names.

  4. Maximal feeding with active prey-switching: A kill-the-winner functional response and its effect on global diversity and biogeography

    Science.gov (United States)

    Vallina, S. M.; Ward, B. A.; Dutkiewicz, S.; Follows, M. J.

    2014-01-01

    Predators' switching towards the most abundant prey is a mechanism that stabilizes population dynamics and helps overcome competitive exclusion of species in food webs. Current formulations of active prey-switching, however, display non-maximal feeding in which the predators' total ingestion decays exponentially with the number prey species (i.e. the diet breadth) even though the total prey biomass stays constant. We analyse three previously published multi-species functional responses which have either active switching or maximal feeding, but not both. We identify the cause of this apparent incompatibility and describe a kill-the-winner formulation that combines active switching with maximal feeding. Active switching is shown to be a community response in which some predators become prey-selective and the formulations with maximal or non-maximal feeding are implicitly assuming different food web configurations. Global simulations using a marine ecosystem model with 64 phytoplankton species belonging to 4 major functional groups show that the species richness and biogeography of phytoplankton are very sensitive to the choice of the functional response for grazing. The phytoplankton biogeography reflects the balance between the competitive abilities for nutrient uptake and the degree of apparent competition which occurs indirectly between species that share a common predator species. The phytoplankton diversity significantly increases when active switching is combined with maximal feeding through predator-mediated coexistence.

  5. Hue opponency: chromatic valence functions, individual differences, cortical winner-take-all opponent modeling, and the relationship between spikes and sensitivity.

    Science.gov (United States)

    Billock, Vincent A

    2018-04-01

    Neural spike rate data are more restricted in range than related psychophysical data. For example, several studies suggest a compressive (roughly cube root) nonlinear relationship between wavelength-opponent spike rates in primate midbrain and color appearance in humans, two rather widely separated domains. This presents an opportunity to partially bridge a chasm between these two domains and to probe the putative nonlinearity with other psychophysical data. Here neural wavelength-opponent data are used to create cortical competition models for hue opponency. This effort led to creation of useful models of spiking neuron winner-take-all (WTA) competition and MAX selection. When fed with actual primate data, the spiking WTA models generate reasonable wavelength-opponent spike rate behaviors. An average psychophysical observer for red-green and blue-yellow opponency is curated from eight applicable studies in the refereed and dissertation literatures, with cancellation data roughly every 10 nm in 18 subjects for yellow-blue opponency and 15 subjects for red-green opponency. A direct mapping between spiking neurons with broadband wavelength sensitivity and human psychophysical luminance yields a power law exponent of 0.27, similar to the cube root nonlinearity. Similarly, direct mapping between the WTA model opponent spike rates and psychophysical opponent data suggests power law relationships with exponents between 0.24 and 0.41.

  6. Modern Multi-line Slot Machine Games: The Effect of Lines Wagered on Winners, Losers, Bonuses, and Losses Disguised as Wins.

    Science.gov (United States)

    Harrigan, K; Dixon, M; Brown, D

    2015-06-01

    We simulated the commercially available multi-line slot machine game "Money Storm," including its bonus wins. Our results show that after a specified amount of time (such as 1 or 50 h), when players played a single line, there were marked differences between one player and the next-a few won a lot, others lost far more than average. When playing 20 lines there were fewer big winners and fewer players quickly losing a large percentage of their money. We simulated a Gambler's Ruin scenario whereby players arrived with $100 and made $1 wagers until broke. Again we saw a reduction in the variability among player as the number of lines wagered increased, fewer players lost their entire bankroll quickly, and fewer players had big wins. The bonus wins in Money Storm contribute approximately 24% to the payback of the game, and our simulations of bonus wins shows that with 20 lines wagered the players spend approximately 11% of their time in bonus wins. With one line wagered, there are no losses disguised as wins while with 20 lines wagered the majority of hits are losses disguised as wins. Players using multi-line machines can thus tune the characteristics of the machine gambling experience to match their preferred pattern, though most seem in practice to bet on the most possible lines. Our results serve to inform researchers, counsellors, gamblers and others about how slot machines are designed, and the effect that wagering on multiple lines has on short-term and long-term play, bonus wins, and losses disguised as wins.

  7. Efficient reinforcement learning of a reservoir network model of parametric working memory achieved with a cluster population winner-take-all readout mechanism.

    Science.gov (United States)

    Cheng, Zhenbo; Deng, Zhidong; Hu, Xiaolin; Zhang, Bo; Yang, Tianming

    2015-12-01

    The brain often has to make decisions based on information stored in working memory, but the neural circuitry underlying working memory is not fully understood. Many theoretical efforts have been focused on modeling the persistent delay period activity in the prefrontal areas that is believed to represent working memory. Recent experiments reveal that the delay period activity in the prefrontal cortex is neither static nor homogeneous as previously assumed. Models based on reservoir networks have been proposed to model such a dynamical activity pattern. The connections between neurons within a reservoir are random and do not require explicit tuning. Information storage does not depend on the stable states of the network. However, it is not clear how the encoded information can be retrieved for decision making with a biologically realistic algorithm. We therefore built a reservoir-based neural network to model the neuronal responses of the prefrontal cortex in a somatosensory delayed discrimination task. We first illustrate that the neurons in the reservoir exhibit a heterogeneous and dynamical delay period activity observed in previous experiments. Then we show that a cluster population circuit decodes the information from the reservoir with a winner-take-all mechanism and contributes to the decision making. Finally, we show that the model achieves a good performance rapidly by shaping only the readout with reinforcement learning. Our model reproduces important features of previous behavior and neurophysiology data. We illustrate for the first time how task-specific information stored in a reservoir network can be retrieved with a biologically plausible reinforcement learning training scheme. Copyright © 2015 the American Physiological Society.

  8. Celebrating Andrew Alm Benson's 93rd birthday.

    Science.gov (United States)

    Govindjee

    2010-09-01

    We celebrate Andy Benson's 93rd birthday on September 24, 2010 through this Editorial. This short account about Andy Benson should serve as a prelude to the short article that Andy has written for the entire photosynthesis community, which gives a glimpse of why he left the field of the "path of carbon in photosynthesis," when he had already discovered, together with Melvin Calvin, James Alan Bassham, and others, most of the major steps in what we now call the Calvin-Benson cycle.

  9. Dreaming with a sense of reality. Winner of the 2004 Royal Shell Award for biofuels research professor Wim van Swaaij; Dromen met realiteitszin. Prof. Wim van Swaaij wint Koninklijke/Shell prijs voor biobrandstoffen-research

    Energy Technology Data Exchange (ETDEWEB)

    De Wit, P. (ed.)

    2004-12-01

    According to the winner of the 2004 Royal Shell Award for Sustainable Development biofuels will play a very important role in the world energy supply. However, the cultivation of energy crops may not be at the expense of the cultivation of crops for food. [Dutch] Biobrandstoffen gaan een zeer belangrijke rol spelen in de wereldenergievoorziening, stelt prof. Wim van Swaaij. Deze winnaar van de Koninklijke/Shell Prijs voor duurzame ontwikkeling 2004 vindt wel dat de teelt van energiegewassen niet ten nadele mag gaan van de teelt van voedingsgewassen.

  10. Genomic Medicine Without Borders: Which Strategies Should Developing Countries Employ to Invest in Precision Medicine? A New "Fast-Second Winner" Strategy.

    Science.gov (United States)

    Mitropoulos, Konstantinos; Cooper, David N; Mitropoulou, Christina; Agathos, Spiros; Reichardt, Jürgen K V; Al-Maskari, Fatima; Chantratita, Wasun; Wonkam, Ambroise; Dandara, Collet; Katsila, Theodora; Lopez-Correa, Catalina; Ali, Bassam R; Patrinos, George P

    2017-11-01

    Genomic medicine has greatly matured in terms of its technical capabilities, but the diffusion of genomic innovations worldwide faces significant barriers beyond mere access to technology. New global development strategies are sorely needed for biotechnologies such as genomics and their applications toward precision medicine without borders. Moreover, diffusion of genomic medicine globally cannot adhere to a "one-size-fits-all-countries" development strategy, in the same way that drug treatments should be customized. This begs a timely, difficult but crucial question: How should developing countries, and the resource-limited regions of developed countries, invest in genomic medicine? Although a full-scale investment in infrastructure from discovery to the translational implementation of genomic science is ideal, this may not always be feasible in all countries at all times. A simple "transplantation of genomics" from developed to developing countries is unlikely to be feasible. Nor should developing countries be seen as simple recipients and beneficiaries of genomic medicine developed elsewhere because important advances in genomic medicine have materialized in developing countries as well. There are several noteworthy examples of genomic medicine success stories involving resource-limited settings that are contextualized and described in this global genomic medicine innovation analysis. In addition, we outline here a new long-term development strategy for global genomic medicine in a way that recognizes the individual country's pressing public health priorities and disease burdens. We term this approach the "Fast-Second Winner" model of innovation that supports innovation commencing not only "upstream" of discovery science but also "mid-stream," building on emerging highly promising biomarker and diagnostic candidates from the global science discovery pipeline, based on the unique needs of each country. A mid-stream entry into innovation can enhance collective

  11. Picking Winners or Making Them?

    DEFF Research Database (Denmark)

    Chase, Robert S.; Christensen, Rikke Nørding

    2010-01-01

    This paper evaluates how a community driven development project in Thailand impacts social capital by using quantitative and qualitative analytic techniques. Propensity score matching and semi-structured interviews are some of the techniques that are used to investigate whether treatment villages...... differ significantly in their social capital characteristics from matched comparison villages. The results show that villages with more trust and stronger norms of collective action were more likely to participate, which may suggest that the project acted as a mechanism to select these social capital...... characteristics. Moreover it appears like the project enhanced other social capital characteristics, such as information sharing, leadership, and empowerment. The presentation is accessible to readers with an intermediate level of statistics. A prior exposure to propensity score matching is helpful...

  12. More honors for Horton Winner

    Science.gov (United States)

    Back, Bill

    The first grand slam in hydrogeology has been achieved by John Cherry (University of Waterloo, Waterloo, Canada). This year's Horton Award recipient, AGU's most prestigious award for hydrologists, (see “John Cherry Wins Horton Award,” p. 91), has also received the O.E. Meinzer Award from the Geological Society of America and has been selected the first Henry Darcy Distinguished Lecturer for the National Water Well Association. The Meinzer Award was given for a “significant body of work” on aquifer contamination that was published in volume 63 of the Journal of Hydrology.

  13. And the Winner is - Acquired

    DEFF Research Database (Denmark)

    Henkel, Joachim; Rønde, Thomas; Wagner, Marcus

    2015-01-01

    New entrants to a market tend to be superior to incumbents in originating radical innovations. We provide a new explanation for this phenomenon, based on markets for technology. It applies in industries where successful entrepreneurial firms, or their technologies, are acquired by incumbents...... that then commercialize the innovation. To this end we analyze an innovation game between one incumbent and a large number of entrants. In the first stage, firms compete to develop innovations of high quality. They do so by choosing, at equal cost, the success probability of their R&D approach, where a lower probability...... the incumbent performs the least radical project. Entrants pick pairwise different projects; the bigger the number of entrants, the more radical the most radical project. Generally, entrants tend to choose more radical R&D approaches and generate the highest value innovation in case of success. We illustrate...

  14. 2015 Gulf Guardian Award Winners

    Science.gov (United States)

    The Gulf of Mexico Program Partnership developed the Gulf Guardian awards as a way to recognize and honor the businesses, community groups, individuals, and agencies that are taking positive steps to keep the Gulf healthy, beautiful and productive.

  15. 2017 Gulf Guardian Award Winners

    Science.gov (United States)

    The Gulf of Mexico Program Partnership developed the Gulf Guardian awards as a way to recognize and honor the businesses, community groups, individuals, and agencies that are taking positive steps to keep the Gulf healthy, beautiful and productive.

  16. Gilbert Newton Lewis: his influence on physical-organic chemists at Berkeley

    International Nuclear Information System (INIS)

    Calvin, M.

    1982-03-01

    A review is presented of the historical contributions of Gilbert N. Lewis to science and a discussion of the influence of Lewis on the research of the members of the physical-organic staff at Berkeley, including Melvin Calvin, during the twenties, thirties and forties. Some specific examples are discussed. Also, the effect of Lewis, his science and administrative concepts in the creation of excellence in a department of chemistry are reviewed

  17. Gilbert Newton Lewis: his influence on physical-organic chemists at Berkeley

    Energy Technology Data Exchange (ETDEWEB)

    Calvin, M.

    1982-03-01

    A review is presented of the historical contributions of Gilbert N. Lewis to science and a discussion of the influence of Lewis on the research of the members of the physical-organic staff at Berkeley, including Melvin Calvin, during the twenties, thirties and forties. Some specific examples are discussed. Also, the effect of Lewis, his science and administrative concepts in the creation of excellence in a department of chemistry are reviewed.

  18. JOHN CALVIN'S PERSPECTIVE ON MUSIC AND WORSHIP, AND ...

    African Journals Online (AJOL)

    mr tomir

    aimed at introducing simple forms of worship and music in the Church, ... music for a great consideration. And youth should be taught this art; for it makes fine skillful people.” 7. This alludes to the importance Luther attached to music. The power and ...... Barber, 1; Richard Arnold, The English Hymn: Studies in a Genre.

  19. Paupertas (poverty) in John Calvin's Institutes | Britz | Acta Theologica

    African Journals Online (AJOL)

    ... to a temporal interim divine involvement. He cautiously upholds a reverent distance in respect of God's knowledge. However, when considering true and credible knowledge of God, the pastor withholds nothing from the splendour of the teaching of Scripture in this regard. In his inscrutable Deitas Dei the Father of Christ is, ...

  20. ON THE TRAIL OF JOHN CALVIN'S PHILOSO- PHY OF LANGUAGE ...

    African Journals Online (AJOL)

    - portant but inadequate. .... This history should be kept alive in memory because it impresses on us the grace and patience of God with .... close bond between the brothers. Sem and Japheth, notwithstanding all the calamities caused by sin.13.

  1. Quantum chemical investigation of thermochemistry in Calvin cycle

    Indian Academy of Sciences (India)

    intermolecular hydrogen bonding has been made for each solute molecule by using theoretically determined values from different sources. These data have been added together to obtain the standard Gibbs free energy. GØ for each molecule in solution. Finally, the free energy change G of each involved reaction has been.

  2. Paupertas (poverty) in John Calvin's Institutes | Britz | Acta Theologica

    African Journals Online (AJOL)

    Acta Theologica. Journal Home · ABOUT THIS JOURNAL · Advanced Search · Current Issue · Archives · Journal Home > Vol 28, No 2 (2008) >. Log in or Register to get access to full text downloads. Username, Password, Remember me, or Register · Download this PDF file. The PDF file you selected should load here if ...

  3. John Calvin's perspective on music and worship, and its implications ...

    African Journals Online (AJOL)

    Different views on worship and music have been expressed by different Reformers. The Reformers rejected some aspects of medieval worship such as the Gregorian chant, the use of elaborate vocal and instrumental music, overly theatrical performances at worship, the unwarranted expense of elaborate ceremonies, ...

  4. The Framing of Calvin Klein: A Frame Analysis of Media Discourse about the August 1995 Calvin Klein Jeans Advertising Campaign.

    Science.gov (United States)

    Tucker, Lauren R.

    1998-01-01

    Deconstructs the "kiddie porn" media frame used by the industry and mainstream media to characterize Klein's ad campaign. Extends scholarship on the construction of youth in the media, showing how the kiddie-porn frame produces and reproduces common-sense beliefs about the nature of youth. Suggests a metadiscourse encompassing the…

  5. Vesto Melvin Slipher (1875-1969) et la naissance de l'astrophysique extragalactique.

    OpenAIRE

    Brémond, Alain

    2008-01-01

    At the beginning of the twentieth century a new domain arouses from astrophysics. Vesto Slipher's work is at the beginning of the way from the concept of nebulae to that of galaxies. Our work is based on the analysis of the Lowell Observatory archives, a review of the periodicals and books in astronomy from this perdiod, as well as numerous historical and philosophical sources. In the introduction, we summarize the knowledge at the end of the ninteenth century. The first section reports Sliph...

  6. Christmas comic caption competition: the winner

    Science.gov (United States)

    2018-02-01

    Thank you to everyone who participated in our December 2017 competition, to fill in the speech bubble for Santa in our special “A very LIGO Christmas” comic, drawn by Nutsinee Kijbunchoo – a physicist and member of the LIGO Collaboration.

  7. Two Nobel Prize winners in two days

    CERN Multimedia

    2006-01-01

    Living legend of physics, Professor Chen Ning Yang, delivered his CERN Colloquium in the Main Auditorium on 12th October (see photo). His numerous contributions to physics include the famous Yang-Mills theory, which underlies the Standard Model of particle physics, and the prediction of parity violation in weak interactions, for which he shared the Nobel prize with T. D. Lee in 1957. The day before, another Nobel laureate, Norman Ramsey, gave a TH Exceptional Seminar in the same auditorium. Ramsey shared the Nobel Prize with Hans G. Dehmelt and Wolfgang Paul in 1989 for developments in atomic precision spectroscopy.

  8. CHDS Announces 2012 Essay Competition Winner

    OpenAIRE

    Center for Homeland Defense and Security

    2012-01-01

    Center for Homeland Defense and Security, PRESS RELEASES The human body’s multi-layered biological defense systems can provide insight into securing increasingly complex information security systems, suggests the winning entry of the Center for Homeland Defense and Security’s 2012...

  9. And the Winner is – Acquired

    DEFF Research Database (Denmark)

    Henkel, Joachim; Rønde, Thomas; Wagner, Marcus

    value in case of success—that is, a more radical innovation. In the second stage, successful entrants bid to be acquired by the incumbent. We assume that entrants cannot survive on their own, so being acquired amounts to a ‘prize’ in a contest. We identify an equilibrium in which the incumbent chooses...

  10. Higgs boson: the winner takes it all?

    CERN Multimedia

    Antonella Del Rosso

    2015-01-01

    Since its discovery in 2012, the Higgs boson has been in the spotlight for both experimentalists and theorists. In addition to its confirmed role in the mass mechanism, recent papers have discussed its possible role in the inflation of the universe and in the matter-antimatter imbalance. Can a single particle be responsible for everything?   “Since 2012 we have known that the Higgs boson exists, but its inner properties are yet to be completely uncovered,” says Gian Giudice, a member of the CERN Theory Unit. “Precise measurements of its decay modes are still ongoing and the LHC Run 2 will be essential to understand the nature of this particle at a deeper level.” What we know is that this boson is not “yet another particle” among the hundreds that we deal with every day in physics labs. In agreement with the Standard Model theory, the recent experimental data confirms that the particle discovered by the CERN experiments is the key pa...

  11. Case Study: "Care" as a Political Winner

    Directory of Open Access Journals (Sweden)

    Meredith Loomis Quinlan

    2017-03-01

    Full Text Available Through face-to-face conversations and open-ended questions designed to elicit stories and deeper interactions, the Michigan People’s Campaign (MPC may have altered voting patterns more effectively than using traditional electoral engagement strategies. During the 2016 election, by campaigning on issues of family care, MPC helped elect a progressive state house candidate in a Downriver Detroit district that Republican presidential candidate Donald Trump carried by over 6,000 votes.

  12. Winners and Losers in Danish Soccer

    DEFF Research Database (Denmark)

    Storm, Rasmus K.

    2011-01-01

    This article deals with the commercialization of European and Danish football, focusing on the Danish male first-tier clubs. Based on the argument drawn from systems theory that sport serves as a mirror system in (late-) modern society, the Danish football clubs are measured against a simple matr...

  13. A Nobel Prize winner visits CERN

    CERN Multimedia

    2007-01-01

    Nobel Prize-winning astrophysicist George Smoot visited CERN on 2 February with a message for particle physicists and cosmologists alike. After a tour of ATLAS and CMS, Smoot gave a talk to a packed Council Chamber about the connections between particle physics and cosmology, and how the two disciplines can help each other to find answers to their cosmic questions. Smoot's group at Lawrence Berkeley National Laboratory is currently working on the development of the Max Planck Surveyor, the next generation of satellite to study cosmic microwave background anisotropy, which will teach us about how our universe was formed.

  14. Bike2Work: and the winners are...

    CERN Multimedia

    Jens Vigen, "Bike2Work" coordinator for CERN

    2015-01-01

    Bike2Work is a popular initiative to promote cycling that was launched in Switzerland in 2004. Every summer, it mobilises some 50,000 employees from more than 1100 companies and organisations across Switzerland. This year, CERN established itself as the main player in French-speaking Switzerland.   The main motivation for Bike2Work is the joy of the cycle commute. Biking contributes to your fitness and reduces pollution and congestion on the roads and in car parks. During this year’s Bike2Work, over 9 million kilometres were recorded across Switzerland! Out of these, 97,462 kilometres were pedaled by the 126 CERN teams participating in the initiative. In this friendly competition, CERN established itself as the main player in French-speaking Switzerland, although EPFL was not far behind with 124 teams. However, CERN beat EPFL by a large margin with regard to the number of kilometres cycled, as our colleagues in the canton of Vaud reached only 63,000 kilometres. Even ETH in Zurich w...

  15. How to Make Your Child a Winner!

    Science.gov (United States)

    Encyclopaedia Britannica, Inc., Chicago, IL.

    Ideas and activities for helping children attain success in school, in friendships and in sports are presented in this handbook for parents. The areas covered are: (1) developing a winning attitude; (2) increasing self-confidence; (3) improving reading skills; (4) gaining good study habits; (5) improving test-taking skills; (6) doing homework; (7)…

  16. Association between mood states and performance of Brazilian elite sailors: Winners vs. non-winners

    Directory of Open Access Journals (Sweden)

    Ricardo Brandt

    2016-01-01

    Full Text Available Debido a sus peculiaridades, la navegación a vela es un deporte que requiere un equilibrio emocional ópti- mo de los atletas para obtener un alto rendimiento, en el que se identificaron seis estados de ánimo como de- cisivos para el mejor rendimiento deportivo; por ejem- plo: alto nivel de vigor y niveles más bajos de tensión, depresión, ira, fatiga y confusión mental. El objetivo de este estudio es evaluar la asociación entre los estados de ánimo y el rendimiento deportivo de los atletas que practican navegación a vela en diferentes competen- cias. Participaron en esta investigación sesenta y dos na- vegantes de alto nivel en clases colectivas e individuales, en cuatro competencias diferentes de vela. Las evalua- ciones se realizaron en los lugares de las competencias y para valorar el estado de ánimo se utilizó la escala de ánimo de Brunel. Los ganadores presentaron diferen- tes estados de ánimo. Atletas con menor depresión ( p < 0.01, ( OR = 0.70 y fatiga ( p < 0.001, (OR = 0.80 y mayor vigor ( p < 0.001, ( OR = 1.26 son más propensos a ganar la competición. Los resultados revelaron la rela- ción entre estados de ánimo y el rendimiento deportivo.

  17. Quem são os vencedores e os perdedores dos jogos olímpicos? Who are the winners and the losers in the olympic games? Quienes son los vencedores y los perdedores de los juegos olímpicos?

    Directory of Open Access Journals (Sweden)

    2006-11-01

    Full Text Available Vencedores e perdedores dos Jogos Olímpicos são normalmente concebidos em termos de resultados esportivos. Todavia, em face das candidaturas de cidades brasileiras à sede dos Jogos, o objetivo deste artigo é investigar como os interesses e efeitos agregados aos Jogos podem gerar ganhos e perdas sociais, políticas e econômicas. Como procedimento, fez-se uma revisão da literatura a respeito das experiências de Jogos anteriores. Enquanto os interesses permitem detectar os vencedores, os efeitos gerados pela concretização dos Jogos indicam os potenciais perdedores com sua realização. Sugere-se que estes efeitos sejam criticamente examinados quando da candidatura de uma cidade brasileira à sede dos Jogos Olímpicos no futuro. PALAVRAS-CHAVE: jogos olímpicos – esporte – educação física. Winners and losers of the Olympic Games are normally determined by their sports results. However, as Brazilian cities have bidded to host the Games, the aim of this article is to investigate how the interests and the effects added to the Games may generate social, political, and economic wins and losses. As a procedure, we have revised the literature with respect to previous Games experiences. As the interests allow us to detect the winners, the effects generated by the accomplishment of the Games indicate the potential losers. We suggest that these effects be critically examined the next time a Brazilian city bids to host the Olympic Games. KEY WORDS: olympic games – sport – physical education. Vencedores y perdedores de los Juegos Olímpicos son normalmente concebidos en términos de resultados deportivos. Aunque, mirando a las candidaturas de ciudades brasileñas la sede de los Juegos, el objetivo de este artículo es investigar como los intereses y efectos agregados a los Juegos pueden generar aumentos y pierdas sociales, políticas y económicas. Como procedimiento, hizo una revisión de la literatura a respecto de las experiencias de

  18. Unconscionability, unfair exploitation and the nature of contract theory: comments on Melvin Eisenberg's ‘Foundational Principles of Contract Law'

    NARCIS (Netherlands)

    Hesselink, M.W.

    2013-01-01

    This short paper contains comments prepared for the 'Foundational Principles of Contract Law Roundtable’ held at Berkeley in January 2013. It discusses the relationships between contract law and democracy, between contract prices and human dignity, and between the American doctrine of

  19. Pan-Baltic Linas Libikas - sometimes Hobbes, sometimes Calvin / Linas Libikas ; interv. Ingrid Nielsen

    Index Scriptorium Estoniae

    Libikas, Linas

    2004-01-01

    Coca-Cola HBC Eesti AS-i turundusjuht olukorrast Baltimaade reklaamiturul, turundusspetsialistide sagedase töökohavahetamise võimalikest põhjustest ning oma eesmärkidest ettevõtte eesotsas. Lisa: Linas Libikas

  20. Carbon dioxide fixation by Calvin-Cycle enzymes improves ethanol yield in yeast

    NARCIS (Netherlands)

    Guadalupe-Medina, V.; Wisselink, H.W.; Luttik, M.A.H.; De Hulster, E.; Daran, J.M.; Pronk, J.T.; Van Maris, A.J.A.

    2013-01-01

    Background Redox-cofactor balancing constrains product yields in anaerobic fermentation processes. This challenge is exemplified by the formation of glycerol as major by-product in yeast-based bioethanol production, which is a direct consequence of the need to reoxidize excess NADH and causes a loss

  1. From Calvin Klein to Paris Hilton and MySpace: adolescents, sex, and the media.

    Science.gov (United States)

    Brown, Jane D; Strasburger, Victor C

    2007-12-01

    In the absence of effective sex education at home or school, the media have become important sources of sexual information for adolescents in the United States. Mainstream media inundate teenagers with sexual images and innuendoes. In the most recent content analysis of American primetime TV, more than three-fourths of the shows had sexual content; yet less than 15% contained any references to responsible sexuality, abstinence, the risk of pregnancy, or the risk of sexually transmitted infections. Dozens of studies attest to the power of the media to influence teenagers' beliefs and attitudes about sex. Three longitudinal studies have all found that adolescents exposed to more sexual content are more likely to begin having sexual intercourse earlier than their peers who see or hear less about sex in the media. The media could become part of the solution as well as part of the problem - if there were more responsible portrayals of human sex and more widespread advertising of birth control products.

  2. John Calvin and the Reformed tradition on the jurisdiction of the church

    Directory of Open Access Journals (Sweden)

    P. Coertzen

    2001-08-01

    Full Text Available John Calvin’s view on the power of jurisdiction in the church, as he writes about it in the Institutes, is expounded in this article. Firstly, attention is given to the spiritual authority of the church, followed by an exposition of the power of the church to exercise jurisdiction. Lastly the current situation in Reformed circles on the jurisdiction of the church is discussed.

  3. Rejecting Dialogue for Perspective: Vygotsky's Zone of Proximal Development and John Calvin's Divine Pedagogy

    Science.gov (United States)

    Horner, Jeffrey Michael

    2017-01-01

    James Estep's integration of Vygotsky's work on the Zone of Proximal Development into Christian education and pedagogy falls short of a distinctly evangelical form of integration. Using Ken Badley's schemata of Integration of Faith and Learning, this article distinguishes Estep's "paradigmatic" integration from a more thoroughgoing…

  4. The Librarian as Winner: Eugenie Prime of Hewlett-Packard.

    Science.gov (United States)

    Searcher, 1997

    1997-01-01

    Eugenie Prime, Manager of Corporate Libraries at Hewlett-Packard Laboratories is interviewed. Discussion focuses on her previous position heading Glendale Adventist Hospital's CINAHL database program; the scope of library services at Hewlett-Packard; content of the company's Web site; change and the role of professional associations and…

  5. Golden Hadrons 2004: and the winners are …

    CERN Multimedia

    2004-01-01

    For the third year running, CERN has awarded a prize to its best LHC suppliers. Three companies were presented with the Golden Hadron 2004. On Friday 30 July, three of the two hundred suppliers for the LHC were presented with Golden Hadron awards by Lyn Evans. This is the third year that the awards have been presented. This year it was the turn of Alstom-MSA (France), Ernesto Malvestiti S.p.A. (Italy) and Simic S.p.A. (Italy) to receive awards, not only for their technical and financial achievements but also for their compliance with contractual deadlines. From left to right: Sandro Ferraris (SIMIC), Guiseppi Ginola (SIMIC), Gérard Grunblatt (ALSTOM), Phillippe Mocaer (ALSTOM), Gianfranco Malvestiti (ERNESTO MALVESTITI), Ernesto Malvestiti (ERNESTO MALVESTITI) Alstom-MSA was awarded the prize for manufacturing superconducting cable for the LHC's main magnets, the dipoles designed to steer the particles round the accelerator and the quadrupoles designed to focus the particle beams. Seven thousand kilometres ...

  6. Shepard Award Winners, Part 1: Dr. Stephen Thacker

    Centers for Disease Control (CDC) Podcasts

    2009-07-22

    This podcast highlights the accomplishments of Dr. Stephen Thacker, recipient of the prestigious 2009 CDC Charles C. Shepard Award.  Created: 7/22/2009 by Centers for Disease Control and Prevention (CDC).   Date Released: 7/22/2009.

  7. Shepard Award Winners, Part 2: Dr. Tracie Williams

    Centers for Disease Control (CDC) Podcasts

    2009-07-29

    This podcast highlights the accomplishments of Dr. Tracie Williams, recipient of the prestigious 2009 CDC Charles C. Shepard Award.  Created: 7/29/2009 by Centers for Disease Control and Prevention (CDC).   Date Released: 7/29/2009.

  8. Shepard Award Winners, Part 3: Dr. Larissa Roux

    Centers for Disease Control (CDC) Podcasts

    2009-09-22

    This podcast highlights the accomplishments of Dr. Larissa Roux, recipient of the prestigious 2009 CDC Charles C. Shepard Award.  Created: 9/22/2009 by Centers for Disease Control and Prevention (CDC).   Date Released: 9/22/2009.

  9. Giving Back — IDRC photo contest winner shares prize with ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    EWB) on a clean-water project in Ziguinchor, a remote town in Senegal. Working with the community, EWB developing a system to draw water from a well using a pump made from a tube, a wheel, rope, and countless pistons. Local resident ...

  10. Nobel Prize winner visits CERN’s superconductors

    CERN Multimedia

    2008-01-01

    On Wednesday 23 April Georg Bednorz, who won the Nobel Prize for physics in 1987, visited CERN along with 44 of his colleagues from the IBM Zurich Research Laboratory. Georg Bednorz (second from right) with colleagues from the IBM Zurich Research Laboratory in the LHC tunnel. On their arrival, Jos Engelen, the Chief Scientific Officer, gave the IBM group an introduction to CERN. Bednorz came to CERN only recently for the Open Days to give a seminar, but unfortunately did not have time to visit the experiments, so this trip was organised instead. Along with Alex Müller, Bednorz was awarded the Noble Prize for his discovery of superconductivity for the so-called high temperature superconductors, essentially copper-oxide-based compounds showing superconductivity at temperatures much higher than had previously been thought possible. The LHC magnets are built with low-temperature superconductors but many current leads that supply power to the LHC cryostats are made with...

  11. The Who's who of Nobel Prize winners, 1901-2000

    National Research Council Canada - National Science Library

    Sherby, Louise S; Odelberg, Wilhelm

    2002-01-01

    ... steamer from New York to Southampton, went by train to Harwich, from there to Esbjerg in Denmark, and so to Sweden. An English gentleman who boarded the boat at Harwich happened to be given a seat at the same dining table as Michelson. During the voyage a somewhat heated discussion ensued between the two of them. The English gentleman spoke dispar...

  12. QUALITY LEADERS - LEARNING FROM THE DEMING PRIZE WINNERS IN INDIA

    Directory of Open Access Journals (Sweden)

    Jagadeesh Rajashekharaiah

    2014-09-01

    Full Text Available Different governments and professional agencies have set up a number of awards to recognize and reward quality initiatives. Deming Prize is one such award and ever since it was open for companies from outside Japan, maximum number of winning companies are from India, with 20 companies winning the Deming Prize and four among them also winning the Deming Grand Prize. This paper traces the path taken by these companies to know how these companies embarked a journey of Total Quality Management (TQM and reached their goal of winning the prestigious Deming Prize. The common working principles of these companies and the various tools and techniques used by them are described in a concise manner in this paper. Further, the paper highlights the lessons from these companies to inspire others. The data taken from the respective websites of the companies has been used to list out the objectives, methodologies, and the benefits accrued by the companies.

  13. Energy prize winner for municipalities; Laureat energia municipalite

    Energy Technology Data Exchange (ETDEWEB)

    Lajoie, R.

    1997-04-01

    Steps taken by the city of Lachine in Quebec to reduce its electricity consumption in the heating and pumping system of its water filtration plant were described. The water treatment plant was built in the 1960`s and treats about 70,000 cubic metres of water daily. The project to retrofit the building gave priority to the pumping room for the water reservoir and to the offices of the building. In an effort to maximize energy consumption and to ensure the comfort of personnel, the following measures were taken: (1) insulation was added to all easily accessible walls, (2) weather stripping was installed on all windows and doors, (3) a fan was installed on the ceiling of the pump room in order to redistribute the heat generated by the water pumps. The total cost of this retrofit was $40,000, and the reported annual savings since the retrofit has been $20,000. A combination of high pressure and low pressure pumping systems have also contributed to a reduction in total energy costs.

  14. Coping with Family Transitions: Winners, Losers, and Survivors.

    Science.gov (United States)

    Hetherington, E. Mavis

    1989-01-01

    Discusses results of a longitudinal study of effects of divorce and remarriage on children's adjustment. Results suggest that individual characteristics play an important role in either protecting children from negative consequences associated with their parents' marital transitions or in making children vulnerable to such consequences. (RJC)

  15. Templeton Prize winner defends Christianity's credibility in a scientific age

    CERN Multimedia

    Heffern, Rich

    2002-01-01

    The 2002 Templeton Prize has gone to the Rev. John C. Polkinghome, a British mathematical physicist and Anglican priest, and a key spokesperson for belief in God in an age of science, defending the ideal that faith is not against science but inconcert with it

  16. Orphan crops can turn into winners | IDRC - International ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    2010-10-06

    Oct 6, 2010 ... The food security of a billion people on the planet is threatened by climate change, increased demand, and volatile prices. In the face of these grave threats, the recent G8 and G20 meetings reaffirmed the need to take urgent action to assure food security for the world's most vulnerable.

  17. Interview with 2018 Hooke medal winner Andrew McAinsh.

    Science.gov (United States)

    2018-03-14

    Andrew McAinsh received his PhD from the University of Cambridge, UK, working in the laboratory of Steve Jackson on DNA damage and repair mechanisms in yeast. He then joined the laboratory of Peter Sorger as a Jane Coffin Childs Fellow to work as a post-doc on kinetochore biology at the Massachusetts Institute of Technology, Boston, USA. In 2005, he returned to the UK to establish his independent laboratory at the Marie Curie Research Institute, Surrey, before moving to the University of Warwick in 2009 to co-found the Centre for Mechanochemical Cell Biology (CMCB). Subsequently, Andrew was appointed Professor of Cell Biology and became a Wellcome Senior Investigator, and was awarded a Royal Society Wolfson Research Merit Award. He co-directs the MRC Doctoral Training Partnership in Interdisciplinary Biomedical Research, and in 2017 became Head of Division of Biomedical Sciences at Warwick Medical School. Andrew is interested in understanding how the chromosomal multi-protein complex, the kinetochore, ensures error-free chromosome segregation. He is the recipient of the 2018 Hooke medal, established to recognize an emerging leader in cell biology. The Hooke medal is awarded at the annual spring meeting of the British Society for Cell Biology (BSCB). © 2018. Published by The Company of Biologists Ltd.

  18. Brain Drain and LDCs' Growth: Winners and Losers

    OpenAIRE

    Michel Beine; Frédéric Docquier; Hillel Rapoport

    2002-01-01

    We present an empirical evaluation of the growth effects of the brain drain for the source countries of migrants. Using recent US data on migration rates by education levels (Carrington and Detragiache, 1998), we find empirical support for the ?beneficial brain drain hypothesis? in a cross-section of 50 developing countries. At the country-level, we find that most countries combining low levels of human capital and low migration rates of skilled workers tend to be positively affected by the b...

  19. And the winner is ... An interview with Brendan Baker | IDRC ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    2011-02-02

    Feb 2, 2011 ... Baker felt a need to highlight the importance of the social and environmental effects of engineering. ... How have your experiences in Senegal changed your attitude towards the developing world? BB: ... What do you think it would take to change Canadians' attitudes toward the developing world? BB:.

  20. Attentional bias in competitive situations: Winner does not take all

    Directory of Open Access Journals (Sweden)

    Zhongqiang eSun

    2015-09-01

    Full Text Available Compared to previous studies of competition with participants’ direct involvement, the current study for the first time investigated the influence of competitive outcomes on attentional bias from a perspective of an onlooker. Two simple games were employed: the Rock-Paper-Scissors game (Experiment 1 in which the outcome is based on luck, and Arm-wrestling (Experiment 2, in which the outcome is based on the competitors’ strength. After observing one of these games, participants were asked to judge a stimulus presented on either the winner’s or loser’s side of a screen. Both experiments yielded the same results, indicating that the onlookers made much quicker judgments on stimuli presented on the loser’s side than the winner’s side. This suggests the existence of an attention bias for loser-related information once a competition has ended. Our findings provide a new lens through which the influence of competition results on human cognitive processing can be understood.

  1. Table tops game:and the winner is...

    CERN Multimedia

    CERN Bulletin

    2010-01-01

    The challenge to identify the events on the coffee tables in Restaurant 1 was clearly a tough one. Congratulations to the few brave entrants! Tuula Maki was the only person to correctly identify all 16 events on the coffee tables in Restaurant 1 and so receives the prize of a copy of the pop-up book, Voyage to the Heart of Matter. An LHC key-ring will go to runners-up Vincent Chabaud,  Eric Jansen, and Andre David Tinoco Mendes, with 14/16 correct.  

  2. And the Winner Is: Inviting Hollywood into the Neuroscience Classroom

    Science.gov (United States)

    Wiertelak, Eric P.

    2002-01-01

    Both short excerpts from, and full-length presentation of feature films have been used with success in undergraduate instruction. Studies of such use of films has revealed that incorporation of film viewing within courses can promote both content mastery and the development of critical thinking skills. This article discusses and provides examples of successful use of two methods that may be used to incorporate a variety of full-length feature films into neuroscience instruction. One, the “neuro-cinema” pairs the presentation of a film featuring extensive neuroscience content with primary literature reading assignments, group discussion and writing exercises. The second, a neuroscience film series, features group discussion of movies of perhaps more limited relevance to neuroscience. An additional goal of this article is provide the reader with initial resources for the selection of potential film titles for use in neuroscience education. Three extensive tables are included to provide a wide range of title suggestions appropriate for use in activities such as the neuro-cinema, the neuroscience film series, or for more limited use as short “clips” in classroom instruction. PMID:23493171

  3. Is the Chinese Army the Real Winner in PLA Reforms

    Science.gov (United States)

    2016-10-01

    increased emphasis on Taiwan contin - gencies and protecting maritime interests in the South and East China seas, all of which required power...traditional status as a continental power. PLAA leaders may have believed that the mission of protecting Chinese territory from invasion was important...able to influence selec- tion, evaluation, and promotion criteria Soldier makes fish trap during survival phase of Exercise Kowari 2016, Australian

  4. Winner of video contest inspired by the LHC

    CERN Document Server

    Laëtitia Pedroso

    2010-01-01

    A video contest was launched this year to mark the 10th anniversary of the Frederick Phineas and Sandra Priest Rose Centre for Earth and Space. Luke Cahill, a 27 year-old BFA graduate, has just won the contest with a movie about CERN.   Luke, who works in the film industry in Los Angeles and also takes physics classes, came across a video promoting the contest while he was browsing the American Natural History Museum website. "It seemed like a perfect opportunity to combine my passion for science with my craft of filmmaking", says Luke. Luke decided to make a video about the LHC. To him, CERN embodies the ideals of scientific progress and discovery, continually expanding the boundaries of our knowledge. "I have never actually been to CERN but it's high on the list of places I want to visit when I travel to Europe", says Luke. There is a lot of misleading information on the Internet about CERN – especially about the LHC. Luke wanted to clarify what the ...

  5. The Looks of a Winner: Beauty, Gender and Electoral Success

    OpenAIRE

    Berggren, Niclas; Jordahl, Henrik; Poutvaara, Panu

    2006-01-01

    We study the role of beauty in politics. For the first time, focus is put on differences in how women and men evaluate female and male candidates and how different candidate traits relate to success in real and hypothetical elections. We have collected 16,218 assessments by 2,772 respondents of photos of 1,929 Finnish political candidates. Evaluations of beauty explain success in real elections better than evaluations of competence, intelli-gence, likability, or trustworthiness. The beauty pr...

  6. Winners and losers – responses to recent environmental change by ...

    African Journals Online (AJOL)

    By contrast, numbers of Cape Gannets Morus capensis and Swift (Crested) Terns Thalasseus bergii increased. The success of the gannet and the tern in the face of recent change is attributable to a rapid increase in South Africa's eastern colony of gannets, aided by high survival of adult birds and perhaps by immigration of ...

  7. Giving Back — IDRC photo contest winner shares prize with ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    2011-01-28

    Jan 28, 2011 ... Local resident Abdoulaye Lo devised a fast and inexpensive way to produce the pistons using plastic recycled from broken buckets. In late 2006, Baker revisited Senegal. Upon his return to Canada, the 26-year-old wrote to IDRC the following postscript to winning the contest: “One huge thrill during the trip ...

  8. Ten NCI Researchers Among Spring Research Festival Award Winners | Poster

    Science.gov (United States)

    In a ceremony at the Fort Detrick Community Activities Center earlier this week, Maj. Gen. Barbara R. Holcomb, the commanding officer of the Fort Detrick garrison, distributed the awards for outstanding presentations and posters at the 2017 Spring Research Festival.

  9. Autotrophic Carbon Dioxide Fixation via the Calvin-Benson-Bassham Cycle by the Denitrifying Methanotroph "Candidatus Methylomirabilis oxyfera"

    NARCIS (Netherlands)

    Rasigraf, O.; Kool, D.M.; Jetten, M.S.M.; Ettwig, K.F.; Sinninghe Damsté, J.S.

    2014-01-01

    Methane is an important greenhouse gas and the most abundant hydrocarbon in the Earth's atmosphere. Methanotrophic microorganisms can use methane as their sole energy source and play a crucial role in the mitigation of methane emissions in the environment. "Candidatus Methylomirabilis oxyfera" is a

  10. A theological re-description of the emergence of religion: In conversation with John Calvin on the semen religionis

    Directory of Open Access Journals (Sweden)

    Ernst Conradie

    2012-05-01

    Full Text Available Where does religion come from? This article suggests that this question may be addressed from the perspectives of various disciplines. An investigation of theological re-descriptions of the emergence of religion may provide insights on the relation between theology and the study of religion. The article explores John Calvin’s views on the semen religionis as a case study of such a theological re-description. Calvin’s account is then compared with Karl Barth’s Christological account. It is observed that a fully trinitarian account of the emergence of religion may be required in this regard. The author concludes that any adequate theological account of this question would provide an ultimate perspective on the emergence of religion that cannot be captured under the generic rubric of “religion”. To do so would amount to a form of reductionism.

  11. Ulrik Huber and John Calvin: The Franeker Debate on Human Reason and the Bible (1686-1687)

    NARCIS (Netherlands)

    Goudriaan, A.

    2011-01-01

    In a doctoral dissertation De recta ratiocinatione (1686), Gisbert Wessel Duker claimed that "the divinity of Scripture cannot be demonstrated except by reason." During the promotion session at the University of Franeker, the legal scholar Ulrik Huber (1636-1694) objected to this statement by

  12. The European Parliament in the 2000 IGC and the Constitutional Treaty negotiations: from loser to winner

    DEFF Research Database (Denmark)

    Beach, Derek

    2007-01-01

      Abstract           Why did two rounds of EU constitutional reform held within a five year period yield very different results? The 2000 IGC resulted in the modest Treaty of Nice, whereas the 2002-04 round drafted the Constitutional Treaty, which although it did not involve major substantive...... changes, did mark a major symbolic step forward. This article argues that the change in outcomes can to a large degree be explained by the change in negotiating structure due to the use of a convention that drafted most of the Constitutional Treaty's text, creating a context which privileged MEPs. While...

  13. Winners, Losers, Insiders, and Outsiders: Comparing Hierometer and Sociometer Theories of Self-Regard

    Science.gov (United States)

    Mahadevan, Nikhila; Gregg, Aiden P.; Sedikides, Constantine; de Waal-Andrews, Wendy G.

    2016-01-01

    What evolutionary function does self-regard serve? Hierometer theory, introduced here, provides one answer: it helps individuals navigate status hierarchies, which feature zero-sum contests that can be lost as well as won. In particular, self-regard tracks social status to regulate behavioral assertiveness, augmenting or diminishing it to optimize performance in such contests. Hierometer theory also offers a conceptual counterpoint that helps resolve ambiguities in sociometer theory, which offers a complementary account of self-regard’s evolutionary function. In two large-scale cross-sectional studies, we operationalized theoretically relevant variables at three distinct levels of analysis, namely, social (relations: status, inclusion), psychological (self-regard: self-esteem, narcissism), and behavioral (strategy: assertiveness, affiliativeness). Correlational and mediational analyses consistently supported hierometer theory, but offered only mixed support for sociometer theory, including when controlling for confounding constructs (anxiety, depression). We interpret our results in terms of a broader agency-communion framework. PMID:27065896

  14. SUSTAINABLE COMPETITIVENESS THROUGH QUALITY TRANSFORMATION: A LONGITUDINAL ANALYSIS OF QUALITY AWARD WINNERS AND A PROPOSED FRAMEWORK

    Directory of Open Access Journals (Sweden)

    Mohd Ashari Idris

    2002-01-01

    Full Text Available Quality management is a dynamic philosophy that underlines the organisational adaptation and proactive transformation that enables firms to reap real benefits from market opportunities. The faster the market changes, the quicker the transformation that is required for sustaining the firm's internal capabilities and its external competitiveness. Under a competitive pressure, a firm will need to learn faster and lead in best practice for operational excellence and continuously finding ways to shield its advantage from imitation.In the search for determinants for sustainability, this article analyses best practices adopted by quality award-winning organisations and synthesises a collection of critical factors that could assist organisations in improving their performance. From a longitudinal learning on how these leading organisations led themselves into a new sustaining paradigm, the article makes explicit the factors that were considered of paramount importance to sustainability. These success factors become a basis for others to leapfrog ahead into a new performance orbit. A proposed model for sustaining competitiveness has been developed from the creative learning of best practices of leading organisations. This proposed framework presents companies with an opportunity to emulate successful implementation of TQ-based initiatives, and to embed these pioneering concepts, particularly in the context of emerging countries.

  15. A six-time Ultraman winner and a normal heart: A case report

    Directory of Open Access Journals (Sweden)

    Claudio Gil Soares de Araújo

    2014-02-01

    Full Text Available Number of subjects currently participating in high-endurance aerobic exercise training regimens and competitions has substantially increased in recent years. While there is no doubt that regular exercise practice is fundamental for the maintenance of a good health, there have been reports of cardiac structural changes of subjects exposed to strenuous endurance physical exercise. This article reports a case of a 47-year-old male very successful sportsman—including being a six-time Ultraman winner—who has accumulated more than 50,000 h of training and competition in his 35-year career, averaging 25–30 h/week. Despite this huge amount of aerobic exercise, about 25 times larger than typically recommended dose for health purposes (i.e. 75 min of vigorous exercise per week, no major abnormalities were detected in electrocardiograms (rest and maximal exercise, transthoracic echocardiogram, and magnetic resonance imaging. In fact, after this complete evaluation, his heart was found to be quite normal.

  16. Swing States, The Winner-Take-All Electoral College, and Fiscal Federalism

    OpenAIRE

    Duquette, Christopher; Mixon, Franklin; Cebula, Richard

    2013-01-01

    There is a debate regarding the impact of swing or independent voters in American politics. While some argue that swing voters either do not swing or have a marginal impact on campaigns, the decline in voter partisan identification and the rise of independents means that they have a potential impact on elections, making them a desirable commodity to candidates. Additionally, presidential elections represent a unique case for swing voters. A robust literature notes that during the presidenti...

  17. Socializing Young Readers: A Content Analysis of Body Size Images in Caldecott Medal Winners

    Science.gov (United States)

    Wedwick, Linda; Latham, Nancy

    2013-01-01

    Many studies have examined gender issues in children's literature, but a review of the literature reveals that few studies have examined the instances of fatness in the images. Studying the fat representation in the images of children's literature is important because exposure to a variety of body types may slow the rate of children's body…

  18. Winners and losers in the complex web of global supply chains.

    Science.gov (United States)

    Glendon, Lee

    2013-01-01

    This paper discusses how supply chain, risk and business continuity professionals can collaboratively address the consequences of increasing supply chain complexity in order to deliver both resilient and sustainable supply chains. The paper identifies the key drivers of complexity supported by recent case examples, including the equine DNA scandal and the Rana Plaza tragedy in Bangladesh.

  19. ISSLS prize winner: cost-effectiveness of two forms of circumferential lumbar fusion

    DEFF Research Database (Denmark)

    Freeman, Brian J C; Steele, Nicholas A; Sach, Tracey H

    2007-01-01

    STUDY DESIGN: Economic evaluation alongside a prospective, randomized controlled trial from a secondary care National Health Service (NHS) perspective. OBJECTIVE: To determine the cost-effectiveness of titanium cages (TC) compared with femoral ring allografts (FRA) in circumferential lumbar spinal...... fusion. SUMMARY OF BACKGROUND DATA: A randomized controlled trial has shown the use of TC to be clinically inferior to the established practice of using FRA in circumferential lumbar fusion. Health economic evaluation is urgently needed to justify the continued use of TC, given that this treatment...... is less effective and, all things being equal, is assumed more costly than FRA. METHODS: Eighty-three patients were randomly allocated to receive either the TC or FRA as part of a circumferential lumbar fusion between 1998 and 2002. NHS costs related to the surgery and revision surgery needed during...

  20. Winners and losers. What are the criteria for success. The service industry

    Energy Technology Data Exchange (ETDEWEB)

    Simmons, M.R.

    1996-12-31

    The paper deals with the oil service company strategies. Following themes are discussed: The oil service shake out; active rig count; oil service industry recovery; listed public upstream oil service companies; international spread of public oil service companies; consolidation has created growth for some; hydrocarbon demand on the march; sample of per capita hydrocarbon demand; hydrocarbon demand model; hydrocarbon impact of new demand and replacing depleting base; ``turning on the tap`` era ending; the oil service bubble evaporates; age of the current fleets; illustration of replacement economics; illustration of operating leverage; new era management challenges. 14 figs.

  1. Winners and Losers in a World with Global Warming: Noncooperation, Altruism, and Social Welfare

    OpenAIRE

    Caplan, Arthur J.; Ellis, Christopher J.; Silva, Emilson C. D.

    1999-01-01

    In this paper, global warming is an asymmetric transboundary externality which benefits some countries or regions and harms others. We use a simple two-country model to analyze the effects of global warming on resource allocations, the global-warming stock, and national and global welfare.

  2. More losers than winners in a century of future Southern Ocean seafloor warming

    Science.gov (United States)

    Griffiths, Huw J.; Meijers, Andrew J. S.; Bracegirdle, Thomas J.

    2017-10-01

    The waters of the Southern Ocean are projected to warm over the coming century, with potential adverse consequences for native cold-adapted organisms. Warming waters have caused temperate marine species to shift their ranges poleward. The seafloor animals of the Southern Ocean shelf have long been isolated by the deep ocean surrounding Antarctica and the Antarctic Circumpolar Current, with little scope for southward migration. How these largely endemic species will react to future projected warming is unknown. By considering 963 invertebrate species, we show that within the current century, warming temperatures alone are unlikely to result in wholesale extinction or invasion affecting Antarctic seafloor life. However, 79% of Antarctica's endemic species do face a significant reduction in suitable temperature habitat (an average 12% reduction). Our findings highlight the species and regions most likely to respond significantly (negatively and positively) to warming and have important implications for future management of the region.

  3. Response of marine copepods to a changing tropical environment: winners, losers and implications

    Directory of Open Access Journals (Sweden)

    Li Lee Chew

    2016-05-01

    Full Text Available Background. Climate change concurrent with anthropogenic disturbances can initiate serial changes that reverberate up the food chain with repercussions for fisheries. To date, there is no information available concerning the combined effects of global warming and human impacts on tropical marine food webs. While temperate copepods respond differently to warming and environmental stressors, the extent to which tropical copepods can adapt to rising temperature of already warm waters remains unknown. We hypothesize that sea warming and other anthropogenic disturbances over the long term will have the greatest impact on the copepod community in nearshore waters where their effects are accentuated, and therefore vulnerable and resilient species could be identified. Methods. Zooplankton samples were collected during two time periods (1985–86 and 2014–15 interposed by marked anthropogenic disturbances, and at the same five stations located progressively from inshore to offshore in Klang Strait, Malaysia, following the asymmetrical before-after-control-impact (BACI design. Copepods were identified to species, and results were interpreted by univariate (ANOVA and multivariate (PERMANOVA, PCO analyses of the computed species abundance and diversity measures. Results. Copepod total abundance was not significantly different among stations but higher after disturbance than before disturbance. However, changes in the abundance of particular species and the community structure between time periods were dramatic. Coastal large-bodied calanoid species (e.g., Acartia spinicauda, Calanopia thompsoni, Pseudodiaptomus bowmani and Tortanus forcipatus were the most vulnerable group to disturbance. This however favored the opportunistic species (e.g., Oithona simplex, O. attenuata, Hemicyclops sp., Pseudomacrochiron sp. and Microsetella norvegica. Small-bodied copepods (e.g., Paracalanus sp., Parvocalanus crassirostris and Euterpina acutifrons were unaffected. Centropages tenuiremis was likely an introduced species. There was no significant loss in species richness of copepods despite the dramatic changes in community structure. Discussion. Sea warming and other human-induced effects such as eutrophication, acidification and coastal habitat degradation are likely the main factors that have altered copepod community structure. The large-bodied estuarine and coastal calanoid copepods are surmised to be vulnerable to eutrophication and hypoxia, while both resilient and opportunistic species are largely unaffected by, or adaptable to, degraded coastal environments and observed sea surface temperature (SST rise. It is forecasted that SST rise with unmitigated anthropogenic impacts will further reduce large-bodied copepod species the favoured food for fish larvae with dire consequences for coastal fish production.

  4. The Status of the Testing Effect for Complex Materials: Still a Winner

    Science.gov (United States)

    Rawson, Katherine A.

    2015-01-01

    The target articles in the special issue address a timely and important question concerning whether practice tests enhance learning of complex materials. The consensus conclusion from these articles is that the testing effect does not obtain for complex materials. In this commentary, I discuss why this conclusion is not warranted either by the…

  5. The Winners and Losers in Finfish Trade in Mafia Island: A Value ...

    African Journals Online (AJOL)

    Fish trade in Mafia involves several players in the value chain from fishing to the plate either in Mafia Island itself and or mainland Tanzania. This paper investigates the different actors in the value chain to establish how much each of them contributes to the process of adding value to fish as a traded commodity in the ...

  6. The Winner Curse and Social Inefficiency: Double Whammy of R&D Tournament

    Directory of Open Access Journals (Sweden)

    Arijit Mukherjee

    2011-11-01

    Full Text Available In a R&D tournament setting with free entry and knowledge spillover, we show that the society would suffer from excessive entry and the patent holder would endure lower profits than non-patent holders because it bears the cost of commercializing and further technology development, while the other firms are beneficiaries of the spillover effects. This result is instructive to R&D and competition policy.

  7. Nobel prize winner returns home to tell a fascinating 'Big Science' story

    Energy Technology Data Exchange (ETDEWEB)

    Angiolillo, C.; Dranga, R. [Canadian Nuclear Laboratories, Chalk River, Ontario (Canada)

    2015-12-15

    This paper is about the Sudbury Neutrino Observatory (SNO) experiment. SNO achieved a major breakthrough on the study of the behavior of an elementary and enigmatic particle of the universe - the neutrino. The experiment was the result of the synthesis of over 30-years of work on particle physics, astrophysics and nuclear science that saw early germination at Chalk River Laboratories. Preliminary SNO results led to a major leap forward on how to measure sub-atomic phenomena that were never used to this extent before and have also provided new insights into the Standard Model of physics, and indeed in our fundamental understanding of the entire universe.

  8. HGSA DNA day essay contest winner 60 years on: still coding for cutting-edge science.

    Science.gov (United States)

    Yates, Patrick

    2013-08-01

    MESSAGE FROM THE EDUCATION COMMITTEE: In 2013, the Education Committee of the Human Genetics Society of Australasia (HGSA) established the DNA Day Essay Contest in Australia and New Zealand. The contest was first established by the American Society of Human Genetics in 2005 and the HGSA DNA Day Essay Contest is adapted from this contest via a collaborative partnership. The aim of the contest is to engage high school students with important concepts in genetics through literature research and reflection. As 2013 marks the 60th anniversary of the discovery of the double helix of DNA by James Watson and Francis Crick and the 10th anniversary of the first sequencing of the human genome, the essay topic was to choose either of these breakthroughs and explain its broader impact on biotechnology, human health and disease, or our understanding of basic genetics, such as genetic variation or gene expression. The contest attracted 87 entrants in 2013, with the winning essay authored by Patrick Yates, a Year 12 student from Melbourne High School. Further details about the contest including the names and schools of the other finalists can be found at http://www.hgsa-essay.net.au/. The Education Committee would like to thank all the 2013 applicants and encourage students to enter in 2014.

  9. Trash + Creativity = Problem Solved: Award Winners Give Plastic Bottles Second Life

    Science.gov (United States)

    Tech Directions, 2007

    2007-01-01

    Judge Harry T. Roman, an electrical engineer and inventor, has selected the best of the crop in the 2006/2007 Tech Directions Inventors Award Competition. The challenge this year called on students to slow the filling of landfills by devising uses for discarded plastic water, juice, soda, and sports-drink bottles. Judge Roman noted "many common…

  10. Robust logistic regression to narrow down the winner's curse for rare and recessive susceptibility variants.

    Science.gov (United States)

    Kesselmeier, Miriam; Lorenzo Bermejo, Justo

    2017-11-01

    Logistic regression is the most common technique used for genetic case-control association studies. A disadvantage of standard maximum likelihood estimators of the genotype relative risk (GRR) is their strong dependence on outlier subjects, for example, patients diagnosed at unusually young age. Robust methods are available to constrain outlier influence, but they are scarcely used in genetic studies. This article provides a non-intimidating introduction to robust logistic regression, and investigates its benefits and limitations in genetic association studies. We applied the bounded Huber and extended the R package 'robustbase' with the re-descending Hampel functions to down-weight outlier influence. Computer simulations were carried out to assess the type I error rate, mean squared error (MSE) and statistical power according to major characteristics of the genetic study and investigated markers. Simulations were complemented with the analysis of real data. Both standard and robust estimation controlled type I error rates. Standard logistic regression showed the highest power but standard GRR estimates also showed the largest bias and MSE, in particular for associated rare and recessive variants. For illustration, a recessive variant with a true GRR=6.32 and a minor allele frequency=0.05 investigated in a 1000 case/1000 control study by standard logistic regression resulted in power=0.60 and MSE=16.5. The corresponding figures for Huber-based estimation were power=0.51 and MSE=0.53. Overall, Hampel- and Huber-based GRR estimates did not differ much. Robust logistic regression may represent a valuable alternative to standard maximum likelihood estimation when the focus lies on risk prediction rather than identification of susceptibility variants. © The Author 2016. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  11. Shared Roles of Halobacteriovorax and Viruses in Bacterial Mortality: The Environment Dictates the Winner

    Science.gov (United States)

    Chen, H.; Laws, E. A.; Gulig, P. A.; Berhane, T. K.; Martin, J. L.; Williams, H.

    2016-02-01

    Bacteriophages (phages) are considered to be a major contributor to bacterial mortality. Although recent evidence shows a similar role for the predatory bacterium, Halobacteriovorax (HBx), this organism has been largely ignored. We designed controlled laboratory microcosm studies to examine and compare the predation of a virus and an HBx strain on Vibrio vulnificus (Vv), under a range of environmental conditions. Predator-prey models were used to simulate the results and interpolated using Matlab software. The results show that although the HBx and virus both preyed on Vv, the magnitudes of their respective responses were different and were largely driven by environmental conditions. In low nutrient seawater, HBx was highly active in preying on Vv, resulting in a 4.4 log reduction of prey within 40 hours, whereas phage contributed little to bacterial mortality. However, when nutrients were added to the seawater, phage was the more active predator. At moderate levels of nutrient concentrations (DNB 1:10 and DNB 1:100) both predators were active. Both virus and HBx grew well at salt concentrations ranging from 9 to 30 ppt. Phage reproduction was optimized at 30 ppt and also occurred at higher levels at 40 and 45 ppt. HBx, on the other hand, grew best at 9 ppt and did not grow at 40 and 45 ppt. At temperatures between 15 and 37˚C both predators grew well. The impact of predation on Vv was positively correlated with temperature. The collective results of this study suggest that both HBx and phages can play significant roles in bacterial mortality and hence in shaping microbial communities and cycling nutrients. However, whether HBx or phages play the larger role in any circumstance may be orchestrated by environmental conditions. These results warrant reconsideration of the roles of different biological agents and the environment in bacteria mortality.

  12. Multi-period emissions trading in the electricity sector-winners and losers

    International Nuclear Information System (INIS)

    Bode, Sven

    2006-01-01

    In the context of controlling greenhouse gas emissions, the directive on a Europe-wide trading scheme may be perceived as one of the most important milestones in recent years. Prior to its start, however, a number of very specific design features have to be agreed upon. Regarding the allocation of allowances, a distribution (almost) free of charge seems to be the most likely choice. An aspect that has interestingly attracted little attention in the past is the question of how to allocate emission rights over time. The following paper analyses different allocation options in multi-period emissions trading that are currently discussed in the European context. The options are applied for the electricity sector which is simulated over two periods. The paper distinguishes between a market effect of emissions trading and compliance costs for meeting the emission reduction obligation. The market effect results from a price increase which is due to the fact that opportunity costs for using allowances must be considered. It turns out that the electricity sector as a whole gains from the introduction of the instrument due to the increase of the electricity price. With regard to the different allocation options, it is found that utilities have different preferences depending on the fuel used

  13. Emotions, immunity and sport: Winner and loser athlete's profile of fighting sport.

    Science.gov (United States)

    Pesce, Mirko; Fratta, Irene La; Ialenti, Valentina; Patruno, Antonia; Ferrone, Alessio; Franceschelli, Sara; Rizzuto, Alessia; Tatangelo, Raffaella; Campagna, Giovanna; Speranza, Lorenza; Felaco, Mario; Grilli, Alfredo

    2015-05-01

    Several studies have focused on the relationship between hormonal changes and affective states in sporting contexts relating to an agonistic outcome. More recently, pro-inflammatory cytokines have also been successfully associated with affective state modulation. The aim of this study was to investigate whether athletes who won or lost show different levels of steroid hormones (testosterone and cortisol), pro-inflammatory cytokine IL-1β, or expressions of anger and anxiety during six training fights in seasonal competitions down to the main seasonal competition. In 25 male kick-boxing athletes (age±SD, 28.68±5.34), anger states (RS score) and anxiety states (AS score) were assessed by STAXI-2 and STAI-Y, respectively. Cortisol (C), testosterone (T) and IL-1β salivary levels were measured by the ELISA method. The saliva samples were taken in the afternoon, 30min prior to the start and 30min from the end of both simulated and official competitions. The results showed that the RS score, T, T/C ratio salivary levels increased during the season, whereas the AS score, C and IL-1β suggested an opposite trend. Close to an official competition, the RS score, T, T/C ratio and IL-1β salivary concentrations were significantly higher, and then decreased during competition. By contrast, the AS score and C levels significantly increased throughout the official competition. In addition, significant differences were found for hormones and IL-1β concentrations as well as psychometric assessment close to the outcome of an official match. Athletes who lost showed an higher AS score and C level, while those who won were characterized by an higher level during the pre-competition RS score, T, T/C ratio, and IL-1β. Note that these factors were positively and significantly correlated at the pre-official competition time, while in a linear regression analysis, IL-1β, T and T/C ratio concentrations explained 43% of the variance in the RS score observed at the same time (adjusted R(2)=0.43, ANOVA Pperformance. Copyright © 2015 Elsevier Inc. All rights reserved.

  14. And the Winner Is … : Inter-Rater Reliability among Scholarship Assessors

    Science.gov (United States)

    Johnston, Lucy; Schluter, Philip J.

    2017-01-01

    With increasing competition for postgraduate research scholarships, awarding processes demand attention and scrutiny. We examine inter-rater reliability for two prestigious New Zealand scholarships, the Shirtcliffe Fellowship and the Gordon Watson Scholarship. For each scholarship, five assessors (three academic; two non-academic) independently…

  15. Norman Ramsey. Nobel Prize Winner in Physics (1989); Norman Ramsey. Premio Nobel de fisica (1989)

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2003-07-01

    Norman Ramsey (Washington 1915) received the Nobel Prize in Physics (shared with con H. G. Dehmelt and W. Paul) for the development of study techniques for Atomic Physics. This tireless researcher participated in the discovery of the Magnetic Resonance Method for Molecular Emission. He invented the hydrogen maser and the hydrogen atomic clock, in addition to being a profile author. (Author)

  16. Following Zahka: Using Nobel Prize Winners' Speeches and Ideas to Teach Economics

    Science.gov (United States)

    Shanahan, Martin P.; Wilson, John K.; Becker, William E.

    2012-01-01

    Over 20 years ago, the late William Zahka (1990, 1998) outlined how the acceptance speeches of those who received the Nobel Memorial Prize in Economic Science could be used to teach undergraduates. This article updates and expands Zahka's work, identifying some of the issues discussed by recent Nobel Laureates, classifying their speeches by topic…

  17. Video of Christian Skau and Martin Raussen's interview with the Abel Prize Winner John Milnor

    DEFF Research Database (Denmark)

    Skau, Christian

    2011-01-01

    The television interview with Abel Laureate John Milnor that was broadcasted on Norwegian television in June is now available on the Abel Prize multimedia page. John Milnor received the Abel Prize «for pioneering discoveries in topology, geometry and algebra» to quote the Abel Committee. King...... Harald presented the Abel Prize to John Milnor at the award ceremony in Oslo, Norway on 24 May. Before the interview there is a short presentation of the award ceremony. John Milnor is interviewed by Martin Raussen and Christian Skau. The Abel Prize that carries a cash award of NOK 6 million (about EUR...

  18. Radiation risk and nuclear medicine: An interview with a Nobel Prize winner

    Energy Technology Data Exchange (ETDEWEB)

    Yalow, R.S.

    1995-12-01

    In a speech given years ago at the Veterans Administration Medical Center, Bronx, NY, Rosalyn S. Yalow, 1977 Nobel Prize recipient for her invention of radioimmunoassay, made several salient points on the perception of fear or hazards from exposure to low-level radiation and low-level radioactive wastes. For the past three years, Yalow has been concerned with the general fear of radiation. In this interview, Newsline solicited Yalow`s views on public perceptions on radiation risk and what the nuclear medicine community can do to emphasize the fact that, if properly managed, the use of isotopes in medicine and other cases is not dangerous.

  19. And the tax winner is ... A note on endogenous timing in the commodity taxation race

    OpenAIRE

    Hubert Kempf; Grégoire Rota-Graziosi

    2010-01-01

    This note investigates the endogenous choice of leadership in commodity tax competition. We apply an endogenous timing game, where jurisdictions commit themselves to lead or to follow, to the Kanbur and Keen (1993) model. We show that the Subgame Pefect Nash Equilibria (SPNE) correspond to the two Stackelberg situations, yielding to a coordination issue. Selecting an equilibrium by means of the risk-dominance criterion, we prove that the smaller country has to lead. If asymmetry among countri...

  20. A lecture by Saul Perlmutter, winner of the 2011 Nobel prize in physics

    CERN Multimedia

    2011-01-01

    The CNRS National Institute of Nuclear Physics and Particle Physics (IN2P3), Pierre et Marie Curie University and the Laboratory of Nuclear and High-energy Physics (LPNHE) are happy to invite you to a talk by Nobel laureate Saul Perlmutter.   Perlmutter shared the 2011 Nobel prize in physics "for the discovery of the accelerating expansion of the Universe through observations of distant supernovae." He will give a public talk in Paris on 17 December at 5pm: "Supernovae, Dark Energy, and the Accelerating Universe" Amphithéâtre Farabeuf des Cordeliers 21, rue de l’école de Médecine 75006 Paris Free entrance (places are limited) and live translation available.

  1. Werner Forssmann - A Nobel Prize Winner and His Political Attitude before and after 1945.

    Science.gov (United States)

    Packy, Lisa-Maria; Krischel, Matthis; Gross, Dominik

    2016-01-01

    In 1956, the Nobel Prize in Physiology or Medicine was awarded jointly to Werner Forssmann, André Frédéric Cournand and Dickinson W. Richards for their development of cardiac catheterization. Forssmann performed a self-experiment in 1929 by inserting a urethral catheter into his right ventricular cavity via his antecubital vein. Despite his popularity as one of the first German Nobel Laureates after 1945, little is known about Forssmann personally. This contribution aims to close this gap regarding the Nazi period and early post-war Germany. Primary historical sources from Forssmann's private archive were examined, evaluated and interpreted for the first time. Additionally, a comparative analysis based on further archival and secondary sources was performed. Werner Forssmann joined the Nazi Party, the Sturmabteilung (Stormtroopers, SA) and the Nationalsozialistischer Deutscher Ärztebund (Nazi Doctors' Association) in 1932, a year before Hitler's assumption of power. In his autobiography, Forssmann referred to the political situation in passing. However, he expressed his personal thoughts in private letters which he wrote as a medical officer during the war. After World War II, Forssmann underwent denazification and was banned from practicing medicine for 3 years. He did not seem to be averse to Hitler's politics and in some ways expressed his approval. However, correspondence from the 1960s with 2 Jewish colleagues reveals that Forssmann may have changed his attitude toward National Socialism later. Werner Forssmann's political attitudes during the Third Reich and in the post-war era can be characterized as early agreement that gradually changed to a more critical distance to Nazi ideology. In this respect, Forssmann appears to be quite a typical example of a larger proportion of German medical doctors during these eras. © 2016 S. Karger AG, Basel.

  2. Nobel prize winner returns home to tell a fascinating 'Big Science' story

    International Nuclear Information System (INIS)

    Angiolillo, C.; Dranga, R.

    2015-01-01

    This paper is about the Sudbury Neutrino Observatory (SNO) experiment. SNO achieved a major breakthrough on the study of the behavior of an elementary and enigmatic particle of the universe - the neutrino. The experiment was the result of the synthesis of over 30-years of work on particle physics, astrophysics and nuclear science that saw early germination at Chalk River Laboratories. Preliminary SNO results led to a major leap forward on how to measure sub-atomic phenomena that were never used to this extent before and have also provided new insights into the Standard Model of physics, and indeed in our fundamental understanding of the entire universe.

  3. Big Bad Banks? The Winners and Losers From Bank Deregulation in the United States

    NARCIS (Netherlands)

    Beck, T.H.L.; Levine, R.; Levkov, A.

    2009-01-01

    We assess the impact of bank deregulation on the distribution of income in the United States. From the 1970s through the 1990s, most states removed restrictions on intrastate branching, which intensified bank competition and improved bank performance. Exploiting the cross-state, cross-time variation

  4. SpineCor treatment for Juvenile Idiopathic Scoliosis: SOSORT award 2010 winner.

    Science.gov (United States)

    Coillard, Christine; Circo, Alin B; Rivard, Charles H

    2010-11-10

    Juvenile idiopathic scoliosis is a condition used to describe patients who are least 4 years of age but younger than 10 when the deformity is first identified. In these patients, the condition is usually progressive and those that are diagnosed at five years or younger have a high chance of progression to a large curve, with additional pulmonary and cardiac complications. The main form of conservative treatment for juvenile scoliosis is the use of a bracing system. This prospective interventional study was conducted to evaluate the effectiveness of the Dynamic SpineCor orthosis for juvenile idiopathic scoliosis as well as to evaluate the stability of the spine after the weaning point. For this study, 150 juvenile patients were treated by the SpineCor orthosis between 1993 and 2009. Of these, 67 patients had a definite outcome and 83 are still actively being treated. To determine the effectiveness of the brace the OUTCOME criteria recommended by the SRS was used. The results from our study showed that of the 67 patients with a definite outcome, 32.9% corrected their Cobb angle by at least 5° and 10.5% had a stabilization of their Cobb angle. Within the patients with a definite outcome, 37.3% of patients where recommended for surgery before authorized end of treatment. For this group of patients, surgery was postponed. Looking at the stability of the curves 2 years after the end of the treatment, we found 12.5% of the patients continued their correction without the brace being used and 71.4% remained stable. From our study we can clearly see that the effectiveness of the SpineCor orthosis in obtaining and maintaining the neuromuscular integration of the corrective movement can be achieved effectively for juvenile patients. Over 75% of all patients that finished the treatment had remained stable with a few continuing to correct their Cobb angle after the use of the SpineCor orthosis was discontinued. Our conclusion from this study is that the SpineCor orthosis is a very effective method of treatment of juvenile idiopathic scoliosis. The results obtained also indicate that treatment outcomes are better with early bracing. Most encouraging perhaps is the fact that the positive outcome appears to be maintained in the long term, and that surgery can be avoided or at least postponed.

  5. SpineCor treatment for Juvenile Idiopathic Scoliosis: SOSORT award 2010 winner

    Directory of Open Access Journals (Sweden)

    Circo Alin B

    2010-11-01

    Full Text Available Introduction Juvenile idiopathic scoliosis is a condition used to describe patients who are least 4 years of age but younger than 10 when the deformity is first identified. In these patients, the condition is usually progressive and those that are diagnosed at five years or younger have a high chance of progression to a large curve, with additional pulmonary and cardiac complications. The main form of conservative treatment for juvenile scoliosis is the use of a bracing system. This prospective interventional study was conducted to evaluate the effectiveness of the Dynamic SpineCor orthosis for juvenile idiopathic scoliosis as well as to evaluate the stability of the spine after the weaning point. Material and Methods For this study, 150 juvenile patients were treated by the SpineCor orthosis between 1993 and 2009. Of these, 67 patients had a definite outcome and 83 are still actively being treated. To determine the effectiveness of the brace the OUTCOME criteria recommended by the SRS was used. Results The results from our study showed that of the 67 patients with a definite outcome, 32.9% corrected their Cobb angle by at least 5° and 10.5% had a stabilization of their Cobb angle. Within the patients with a definite outcome, 37.3% of patients where recommended for surgery before authorized end of treatment. For this group of patients, surgery was postponed. Looking at the stability of the curves 2 years after the end of the treatment, we found 12.5% of the patients continued their correction without the brace being used and 71.4% remained stable. Discussion From our study we can clearly see that the effectiveness of the SpineCor orthosis in obtaining and maintaining the neuromuscular integration of the corrective movement can be achieved effectively for juvenile patients. Over 75% of all patients that finished the treatment had remained stable with a few continuing to correct their Cobb angle after the use of the SpineCor orthosis was discontinued. Conclusion Our conclusion from this study is that the SpineCor orthosis is a very effective method of treatment of juvenile idiopathic scoliosis. The results obtained also indicate that treatment outcomes are better with early bracing. Most encouraging perhaps is the fact that the positive outcome appears to be maintained in the long term, and that surgery can be avoided or at least postponed.

  6. Teaching and Learning Competent Historical Documentary Making: Lessons from National History Day Winners

    Science.gov (United States)

    Fehn, Bruce R.; Schul, James E.

    2011-01-01

    Today's students grow up in a technological milieu of hand-held computers with high storage capacities, internet access, and the ability to shoot high definition photographs and video. As such, they are empowered to construct representations of the past virtually "on the run." In this article, the authors investigated the historical "and"…

  7. [Ilya Ilich Metchnikov and Paul Ehrlich: 1908 Nobel Prize winners for their research on immunity].

    Science.gov (United States)

    Lokaj, J; John, C

    2008-11-01

    The Nobel Prize in Physiology or Medicine in 1908 was awarded to Ilya I. Mechnikov and Paul Ehrlich for recognition of their work on immunity. Mechnikov have discovered phagocytes and phagocytosis as the basis of natural cellular immunity. His ,,phagocytic theory" is the principle of immunological concept "self and not self" as the prerequisition of physiological inflammation, and selfmaintaining of organism. Ehrlich developed the methods for standardization of antibody activity in immune sera, described neutralizing and complement-depending effect of antibodies and enunciated the ,"ide-chain" theory of the formation of antibodies. Their concept of the key-stone of immunity was different, but they expressed the basic paradigma of immunology: immunity imply the protection of identity and guarantee the integrity of organism. Both are the founders of immunology as the scientific discipline. Discoveries and conceptions of I. Mechnikov and P. Ehrlich exceedingly influenced development of immunology and are also applicable, instructive and suggestive in contemporary immunology and microbiology.

  8. Creativity in Early and Established Career: Insights into Multi-Level Drivers from Nobel Prize Winners

    Science.gov (United States)

    Eubanks, Dawn L.; Palanski, Michael E.; Swart, Juani; Hammond, Michelle M.; Oguntebi, Joy

    2016-01-01

    The freedom to try new things plays a vital role for employees engaging in creative endeavors. This freedom can be influenced by one's relationship with her supervisor, relationship with her team, and various work pressures. One of the first steps to reaching creative output is to have a playful attitude toward work where there is encouragement…

  9. Relative health performance in BRICS over the past 20 years: the winners and losers.

    Science.gov (United States)

    Petrie, Dennis; Tang, Kam Ki

    2014-06-01

    To determine whether the health performance of Brazil, the Russian Federation, India, China and South Africa--the countries known as BRICS--has kept in step with their economic development. Reductions in age- and sex-specific mortality seen in each BRICS country between 1990 and 2011 were measured. These results were compared with those of the best-performing countries in the world and the best-performing countries with similar income levels. We estimated each country's progress in reducing mortality and compared changes in that country's mortality rates against other countries with similar mean incomes to examine changes in avoidable mortality. The relative health performance of the five study countries differed markedly over the study period. Brazil demonstrated fairly even improvement in relative health performance across the different age and sex subgroups that we assessed. India's improvement was more modest and more varied across the subgroups. South Africa and the Russian Federation exhibited large declines in health performance as well as large sex-specific inequalities in health. Although China's levels of avoidable mortality decreased in absolute terms, the level of improvement appeared low in the context of China's economic growth. When evaluating a country's health performance in terms of avoidable mortality, it is useful to compare that performance against the performance of other countries. Such comparison allows any country-specific improvements to be distinguished from general global improvements.

  10. A very special visit to ATLAS: America's Cup Winner Team Alinghi

    CERN Multimedia

    Jenni, P

    It is an honour for ATLAS to frequently welcome in its cavern and the assembly sites VIP visits by Heads of State, Ministers, Directors of Funding Agencies and other political dignitaries. Rarely, however, have we had such an illustrious and competent visitor group as on December 3rd, 2003, when the full Research and Design Team from the Swiss America's Cup Team Alinghi looked at the ATLAS integration work in Halls 180 and 191 and visited Pit-1. The Team was led by 'their' Technical Coordinator Grant Simmer and principal designer Rolf Vrolijk. The Alinghi R&D team spans a very broad range of engineering and management competence; just to list a few of the team's special skills: mechanical and material engineering, electronics and software engineering, sail design, construction management, performance analysis and predictions, and last but not least direct feedback from the actual sailing team (strategist Murray Jones). Amazingly there are a lot of commonalities between Team Alinghi and ATLAS which made...

  11. Winners and losers of state electricity boards reforms an organisational analysis

    Energy Technology Data Exchange (ETDEWEB)

    Ruet, J.

    2001-01-01

    The power sector in India is often described - in newspapers, in official reports, in reform programmes - as too 'poor' in money... and too 'rich' in politicians. These analyses hence propose corporatisation, un-bundling, setting up of regulatory commissions, as a vade mecum. The sole problem is that they have proved insufficient in improving the health of State Electricity Boards (SEBs). The ultimate tool, privatisation, has also been a deceptive one. This paper suggests that the above analyses should be balanced and completed with another element: the internal organisation itself of SEBs has to be questioned, which, surprisingly enough, is not done in the current reforms. This is not done because SEBs actually behave and are organised as administrations, whose objectives are different from those of a public enterprise. This is not done because consultants implicitly regard SEBs as inefficient enterprises. This paper thus enters into the black box of SEBs, and shows why and how the behaviour of its agents is rational, given the administrative system in which they are. It gives some practical ways to change this system, by developing on the 'enterprisation' of SEBs (turning them from bodies with an administration-style way of running into actual public enterprises), a concept which was coined from the reforms in Eastern Europe. But ultimately reforms are not undertaken per se. Their final aim is a better quality and availability to the people. Their impact on various categories of users and stakeholders can be discussed within this framework of enterprisation, to establish on which conditions reforms can be beneficial to everybody but the 'waste consumer'. This article is mainly based on repeated field inquires in Haryana, Andhra Pradesh and Orissa, at different stages of reform. In these States, the reform, far from precluding to analyse what are classical SEBs, brought to light some processes formerly in the dark. This article aims at giving a detailed analysis of the working and the rationality within the 'black box' that SEBs represent for many consultants. Indeed, SEBs are too often described as irrational bodies, and simplistic explanations in terms of 'political interference' or 'lack of credit' are given as reasons. Since the author feels that one cannot reform an organisation without understanding it from within, these rather narrow statements are discussed in section I. The systemic rationality of SEBs which is discussed in section II, shows the way the internal organisation of SEBs itself coherently leads to certain kind of decisions, at the expense of efficiency. It also focuses on how far the various organisational characteristics of SEBs are mutually enforcing. Section III points out that the 'structural reforms' taking place at the moment in India, do not substantially modify this systemic logic. It therefore calls for the very 'enterprisation' of SEBs (turning them from bodies with administrative functioning into actual public enterprises). Finally, all these analyses aim at casting a new light on the debate on privatisation. Section IV primarily shows that enterprisation is a prerequisite to proper privatisation, and that the question of 'whether to privatize or not' is less stringent than the one of 'how to enterprise'. Indeed, privatisation, like any economic tool, has its pros and cons. The very rationale of this article is based on the fact that in the present state of the Indian power sector, privatisation presents many cons, simply because investors are reluctant to bid. Since the push for privatisation is propelled by partly misleading visions of SEBs as being too rich in politicians and too poor in funds, this article attempts to focus on these arguments and their limits. (author)

  12. 77 FR 64851 - Announcement Date Postponed for the Grand Prize Winner Announcement for the America COMPETES...

    Science.gov (United States)

    2012-10-23

    ... for the America COMPETES Reauthorization Act of 2011: Project REACH Homelessness Mobile App Contest...'s Project REACH Homelessness Mobile App Contest, authorized under section 105 of the America... end Veteran homelessness. This notice serves as an update to the original notice affecting only the...

  13. Strategic Decisions & Staff Collaboration Highlight the 2009 Award for Excellence Winners

    Science.gov (United States)

    Becker, J. Thomas; Taylor, Matthew M.; Lewis, Dan; Ertzberger, Michelle

    2009-01-01

    APPA's highest institutional honor, the Award for Excellence (AFE) in Facilities Management, recognizes those educational institutions whose facilities management organizations demonstrate quality in overall operations and effectiveness. Fewer than 40 institutions have received this distinct honor. The Award for Excellence is based on a set of…

  14. When Winners Become Losers: Predicted Nonlinear Responses of Arctic Birds to Increasing Woody Vegetation.

    Directory of Open Access Journals (Sweden)

    Sarah J Thompson

    Full Text Available Climate change is facilitating rapid changes in the composition and distribution of vegetation at northern latitudes, raising questions about the responses of wildlife that rely on arctic ecosystems. One widely observed change occurring in arctic tundra ecosystems is an increasing dominance of deciduous shrub vegetation. Our goals were to examine the tolerance of arctic-nesting bird species to existing gradients of vegetation along the boreal forest-tundra ecotone, to predict the abundance of species across different heights and densities of shrubs, and to identify species that will be most or least responsive to ongoing expansion of shrubs in tundra ecosystems. We conducted 1,208 point counts on 12 study blocks from 2012-2014 in northwestern Alaska, using repeated surveys to account for imperfect detection of birds. We considered the importance of shrub height, density of low and tall shrubs (i.e. shrubs >0.5 m tall, percent of ground cover attributed to shrubs (including dwarf shrubs <0.5 m tall, and percent of herbaceous plant cover in predicting bird abundance. Among 17 species considered, only gray-cheeked thrush (Catharus minimus abundance was associated with the highest values of all shrub metrics in its top predictive model. All other species either declined in abundance in response to one or more shrub metrics or reached a threshold where further increases in shrubs did not contribute to greater abundance. In many instances the relationship between avian abundance and shrubs was nonlinear, with predicted abundance peaking at moderate values of the covariate, then declining at high values. In particular, a large number of species were responsive to increasing values of average shrub height with six species having highest abundance at near-zero values of shrub height and abundance of four other species decreasing once heights reached moderate values (≤ 33 cm. Our findings suggest that increases in shrub cover and density will negatively affect abundance of only a few bird species and may potentially be beneficial for many others. As shrub height increases further, however, a considerable number of tundra bird species will likely find habitat increasingly unsuitable.

  15. Wonder Woman: Eliza Dresang, Winner of the Scholastic Library Publishing Award

    Science.gov (United States)

    Whelan, Debra Lau

    2007-01-01

    This article features Eliza Dresang, an award-winning author, and her achievements. Dresang was responsible for making a radical shift in how teachers and parents understand modern children literature when she wrote her groundbreaking book, "Radical Change." She found the motivation to write this book after realizing how teachers and parents were…

  16. US Baltic Foundation award winners from Estonia are Arvo Pärt and Enn Kunila

    Index Scriptorium Estoniae

    2010-01-01

    Washingtonis toimunud tänavusel U.S Baltic Foundationi auhinnagalal tunnustati kahte eestlast: helilooja Arvo Pärti auhinnaga Baltimaade kuvandi rikastamise eest (Baltic Image Enhancement Award) ja ettevõtjast kunstikollektsionääri Enn Kunilat Baltimaade filantroopiaauhinnaga

  17. Sounds like a winner: voice pitch influences perception of leadership capacity in both men and women.

    Science.gov (United States)

    Klofstad, Casey A; Anderson, Rindy C; Peters, Susan

    2012-07-07

    It is well known that non-human animals respond to information encoded in vocal signals, and the same can be said of humans. Specifically, human voice pitch affects how speakers are perceived. As such, does voice pitch affect how we perceive and select our leaders? To answer this question, we recorded men and women saying 'I urge you to vote for me this November'. Each recording was manipulated digitally to yield a higher- and lower-pitched version of the original. We then asked men and women to vote for either the lower- or higher-pitched version of each voice. Our results show that both men and women select male and female leaders with lower voices. These findings suggest that men and women with lower-pitched voices may be more successful in obtaining positions of leadership. This might also suggest that because women, on average, have higher-pitched voices than men, voice pitch could be a factor that contributes to fewer women holding leadership roles than men. Additionally, while people are free to choose their leaders, these results clearly demonstrate that these choices cannot be understood in isolation from biological influences.

  18. Losers and winners in coral reefs acclimatized to elevated carbon dioxide concentrations

    Science.gov (United States)

    Fabricius, Katharina E.; Langdon, Chris; Uthicke, Sven; Humphrey, Craig; Noonan, Sam; de'Ath, Glenn; Okazaki, Remy; Muehllehner, Nancy; Glas, Martin S.; Lough, Janice M.

    2011-06-01

    Experiments have shown that ocean acidification due to rising atmospheric carbon dioxide concentrations has deleterious effects on the performance of many marine organisms. However, few empirical or modelling studies have addressed the long-term consequences of ocean acidification for marine ecosystems. Here we show that as pH declines from 8.1 to 7.8 (the change expected if atmospheric carbon dioxide concentrations increase from 390 to 750ppm, consistent with some scenarios for the end of this century) some organisms benefit, but many more lose out. We investigated coral reefs, seagrasses and sediments that are acclimatized to low pH at three cool and shallow volcanic carbon dioxide seeps in Papua New Guinea. At reduced pH, we observed reductions in coral diversity, recruitment and abundances of structurally complex framework builders, and shifts in competitive interactions between taxa. However, coral cover remained constant between pH 8.1 and ~7.8, because massive Porites corals established dominance over structural corals, despite low rates of calcification. Reef development ceased below pH 7.7. Our empirical data from this unique field setting confirm model predictions that ocean acidification, together with temperature stress, will probably lead to severely reduced diversity, structural complexity and resilience of Indo-Pacific coral reefs within this century.

  19. Prior contest experience exerts a long-term influence on subsequent winner and loser effects

    Science.gov (United States)

    2011-01-01

    Introduction Animals are capable of using information from recent experiences to modify subsequent behavioral responses. Animals' ability or propensity to modify their behavior in the light of new information has repeatedly been shown to correlate with, or be influenced by, either their intrinsic competitive ability or their dominance experience - an influence which can be long-lasting. Using a mangrove killifish, Kryptolebias marmoratus, as the study organism, we investigated whether and if so how the effect of a winning or a losing experience one day prior to a dyadic contest was modulated by both competitive ability measured two months previously and a winning or losing experience forced on the contestants one month previously. Results Winning/losing experience forced on the fish one month previously affected how they utilized information from their winning/losing experience one day before Test Day: Individuals that were randomly assigned a losing experience one month previously were more susceptible to the influence of their 1-day winning/losing experience than those assigned a winning experience. Competitive ability measured two months previously, winning/losing experience from one month previously and the winning/losing experience received one day previously all significantly influenced the fish's contest behaviors on Test Day, although only 2-month competitive ability significantly influenced escalation duration, indicating that it was still a good index for the fish's competitive ability two months later. Conclusions These results suggest that the value to the fish of information from a recent win or loss depends on the outcome of their past contests and show that contest experience has a long-term effect on contest behavior. PMID:22051441

  20. Winners, Losers, Insiders, and Outsiders: Comparing Hierometer and Sociometer Theories of Self-Regard.

    Science.gov (United States)

    Mahadevan, Nikhila; Gregg, Aiden P; Sedikides, Constantine; de Waal-Andrews, Wendy G

    2016-01-01

    What evolutionary function does self-regard serve? Hierometer theory, introduced here, provides one answer: it helps individuals navigate status hierarchies, which feature zero-sum contests that can be lost as well as won. In particular, self-regard tracks social status to regulate behavioral assertiveness, augmenting or diminishing it to optimize performance in such contests. Hierometer theory also offers a conceptual counterpoint that helps resolve ambiguities in sociometer theory, which offers a complementary account of self-regard's evolutionary function. In two large-scale cross-sectional studies, we operationalized theoretically relevant variables at three distinct levels of analysis, namely, social (relations: status, inclusion), psychological (self-regard: self-esteem, narcissism), and behavioral (strategy: assertiveness, affiliativeness). Correlational and mediational analyses consistently supported hierometer theory, but offered only mixed support for sociometer theory, including when controlling for confounding constructs (anxiety, depression). We interpret our results in terms of a broader agency-communion framework.

  1. Lecture by the winner of the 2007 Nobel Prize for physics

    CERN Multimedia

    2007-01-01

    Professor Albert Fert, who has just been awarded the Nobel Prize for physics for his work on giant magneto-resistance and spintronics, will give a lecture at the University of Geneva on 16 November on this booming field of science. (c) CNRS Photothèque - C. LebedinskyOn 9 October, the 2007 Nobel Prize for physics was jointly awarded to Albert Fert of the CNRS and Peter Grünberg of the Jülich Research Centre for their simultaneous and independent discovery of giant magneto-resistance (GMR) in 1988. This discovery had a significant impact in the fields of information technology and communications as it was rapidly used to develop extremely sensitive hard disk read-out heads that are capable of reading information stored at very high densities, thereby allowing further progress in the miniaturisation of data-storage devices. Since the first GMR read-out head was launched in 1997, the technology has become the standard in the m...

  2. Winners and losers. What are the criteria for success. The service industry

    International Nuclear Information System (INIS)

    Simmons, M.R.

    1996-01-01

    The paper deals with the oil service company strategies. Following themes are discussed: The oil service shake out; active rig count; oil service industry recovery; listed public upstream oil service companies; international spread of public oil service companies; consolidation has created growth for some; hydrocarbon demand on the march; sample of per capita hydrocarbon demand; hydrocarbon demand model; hydrocarbon impact of new demand and replacing depleting base; ''turning on the tap'' era ending; the oil service bubble evaporates; age of the current fleets; illustration of replacement economics; illustration of operating leverage; new era management challenges. 14 figs

  3. From the Performance Principle to the Developmental Principle: Every Kid a Winner?

    Science.gov (United States)

    Ingham, Alan G.; Chase, Melissa A.; Butt, Joanne

    2002-01-01

    Addresses the hegemony of the Prolympic system, especially its effects on children, asserting that it abrogates the liberal democratic promise that all people are entitled to develop their talents to the fullest extent and making suggestions to combine sport psychology and sociology when thinking about a sport pedagogy system oriented to…

  4. And the winner of the Golden CinéGlobe is…

    CERN Multimedia

    Laëtitia Pedroso

    2010-01-01

    Three years after the first CinéGlobe festival, the CERN film club has just organised a second international festival of short films and science documentaries, attended by a host of film-makers and film fans alike. Six special prizes were awarded.   One of the Golden CinéGlobe awards The second Golden CinéGlobe award ceremony was held in the Globe on the evening of Saturday, 20 February. Now something of a magnet for local fans of short films and science documentaries, the CinéGlobe festival has become one of the most successful events organised by a CERN club. "Organising the festival has been a gratifying experience as many people have taken part in and enjoyed the event", says Quentin King, vice-chairman of the CERN film club, Open Your Eyes Films. "Time was our worst enemy. It took us a year to bring the project to fruition but we could have done with another year to refine some of the details". The 18 screenings...

  5. The hidden winners of renewable energy promotion: Insights into sector-specific wage differentials

    International Nuclear Information System (INIS)

    Antoni, Manfred; Janser, Markus; Lehmer, Florian

    2015-01-01

    In light of Germany's energy system transformation, this paper examines differences in employment structures and wage differentials between renewable energy establishments and their sector peers. To do so, we have developed a novel data set by linking company-level information from the German Renewable Energy Federation with administrative establishment-level data from the Institute for Employment Research. Descriptive evidence shows significant differences in wages and several other characteristics between renewable energy establishments and their sector peers. Our estimates give evidence that human capital and other establishment-level characteristics mostly explain the wage differential among manufacturers and energy providers. However, we find a persistent ‘renewable energy wage premium' of more than ten percent in construction/installation activities and architectural/engineering services. We interpret this premium as a positive indirect effect of the promotion of renewable energies for the benefit of employees in renewable energy establishments within these two sectors. - Highlights: • Renewable energy (RE) firms pay considerably more than their non-RE sector peers. • In manufacturing and energy supply, firm attributes explain mainly the wage gap. • In installation, planning and project management one third remains unexplained. • This unexplained rest represents a ‘RE wage premium’ of around 10 percent. • The employees in both sectors are the ‘hidden winners’ of RE promotion.

  6. No clear winner: effects of The Biggest Loser on the stigmatization of obese persons.

    Science.gov (United States)

    Yoo, Jina H

    2013-01-01

    Previous research has largely ignored the question of whether watching reality weight-loss TV shows influences viewers to form a negative obesity stereotype. This study examines antecedents and outcomes of watching The Biggest Loser with the Orientation1-Stimulus-Orientation2-Response (O-S-O-R) model. The study found that individuals who are more concerned with their weight (O1) watch more episodes of The Biggest Loser (S). Meanwhile, consumption of The Biggest Loser leads to greater perceived locus of weight control (O2), indicating that body weight is under personal control. Perceived locus of weight control, in turn, significantly predicts the attribution of obesity to personal responsibility (R). Ultimately, attributing obesity to personal responsibility leads to the formation of anti-fat attitudes (R). This study offers an integrative theoretical framework to investigate media effects on the formation of an obesity stigma by using the O-S-O-R model. The results imply that certain lifestyle transformation media, such as The Biggest Loser, might reinforce the notion that individuals control their own weight and thus further amplify the obesity stigma.

  7. The European Metropolis in the late Twentieth Century: Winners and Losers

    NARCIS (Netherlands)

    P. Clark (Peter)

    2003-01-01

    textabstractThis paper offers a commentary on some of the recent work on globalisation in the context of the European city in the late 20th century. It points out that the current European urban hierarchy has a strong historical dimension. It notes the considerable degree of convergence in the

  8. [Competition between physicians and hospitals--are hospitals the big winners?].

    Science.gov (United States)

    Sobhani, Bidjan; Kersting, Thomas

    2009-01-01

    Competition and cooperation are contradictory aspects of economic systems; in the healthcare system they also govern the process of creation and distribution of value. Both are needed to reach higher levels of efficiency and innovation. Regarding competition as a universal remedy which only has to be applied in higher doses in order to cure the multiple illnesses of the healthcare sector is a single-sided view and does not match economic reality. As politics introduce more and more elements of competition the question arises as to what degree hospitals are in competition with private practice physicians. In contrast to statements of lobbyists we came to the conclusion that the degree of competition between hospitals and physicians is negligible when compared to the vast potential of cooperation.

  9. CiSE Computational Physics Challenge Winner: Electron Wave Packet Propagation in Graphene Nanoribbons

    Science.gov (United States)

    Anton, Steven M.

    2008-04-01

    While graphene has been studied by theoreticians for over half a century, the two dimensional crystal lattice has only recently been realized experimentally. As such, theoretical work in the properties of graphene has exploded. A variety of these properties, which are truly exceptional and unique, have engendered much research into carbon based electronics, of which graphene is generally the most fundamental unit. In this thesis, we seek to characterize basic electronic properties of graphene nanoribbons. We begin with a tight-binding model of graphene and an analysis of the electronic band structure of the infinite sheet and semi-infinite nanoribbons. Also employing the spectral method, we create, inject, and propagate various types of wave packets infinite wires. A key effect that is expected is the so called Zitterbewegung oscillation of the wave packet center. Results are compared to theoretical predictions based on analytical methods rather than numerical simulations.

  10. Winners, Losers, Insiders, and Outsiders: Comparing Hierometer and Sociometer Theories of Self-Regard

    Directory of Open Access Journals (Sweden)

    Nikhila eMahadevan

    2016-03-01

    Full Text Available What evolutionary function does self-regard serve? Hierometer theory, introduced here, provides one answer: it helps individuals navigate status hierarchies, which feature zero-sum contests that can be lost as well as won. In particular, self-regard tracks social status to regulate behavioral assertiveness, augmenting or diminishing it to optimize performance in such contests. Hierometer theory also offers a conceptual counterpoint that helps resolve ambiguities in sociometer theory, which offers a complementary account of self-regard’s evolutionary function. In two large-scale cross-sectional studies, we operationalized theoretically relevant variables at three distinct levels of analysis, namely, social (relations: status, inclusion, psychological (self-regard: self-esteem, narcissism, and behavioral (strategy: assertiveness, affiliativeness. Correlational and mediational analyses consistently supported hierometer theory, but offered only mixed support for sociometer theory, including when controlling for confounding constructs (anxiety, depression. We interpret our results in terms of a broader agency-communion framework.

  11. Performance management excellence among the Malcolm Baldrige National Quality Award Winners in Health Care.

    Science.gov (United States)

    Duarte, Neville T; Goodson, Jane R; Arnold, Edwin W

    2013-01-01

    When carefully constructed, performance management systems can help health care organizations direct their efforts toward strategic goals, high performance, and continuous improvement needed to ensure high-quality patient care and cost control. The effective management of performance is an integral component in hospital and health care systems that are recognized for excellence by the Malcolm Baldrige National Quality Award in Health Care. Using the framework in the 2011-2012 Health Care Criteria for Performance Excellence, this article identifies the best practices in performance management demonstrated by 15 Baldrige recipients. The results show that all of the recipients base their performance management systems on strategic goals, outcomes, or competencies that cascade from the organizational to the individual level. At the individual level, each hospital or health system reinforces the strategic direction with performance evaluations of leaders and employees, including the governing board, based on key outcomes and competencies. Leader evaluations consistently include feedback from internal and external stakeholders, creating a culture of information sharing and performance improvement. The hospitals or health care systems also align their reward systems to promote high performance by emphasizing merit and recognition for contributions. Best practices can provide a guide for leaders in other health systems in developing high-performance work systems.

  12. Alvin C. Kraenzlein, DDS and Walter B. Tewksbury, DDS: Olympic medal winners.

    Science.gov (United States)

    Christen, A G; Christen, J A

    2001-11-01

    As contemporaries, Alvin C. Kraenzlein, and Walter B. Tewksbury had a great deal in common. They were both outstanding athletic performers and each became an intercollegiate record holder in track and field. In 1898, the New York Times reported that the University of Pennsylvania "at present has the best college athletes in the world, its two particular stars being Kraenzlein and Tewksbury." As close friends and college roommates during their student years at the University of Pennsylvania College of Dentistry, these two young men graduated in close succession (Walter, 1899; Alvin, 1900). Between them, Alvin and Walter won nine Olympic medals in Paris in 1900. Ultimately, as dentists and athletes, they individually and corporately left indelible imprints on track and field for all time.

  13. Tryptophan biosynthesis in stramenopiles: eukaryotic winners in the diatom complex chloroplast

    Czech Academy of Sciences Publication Activity Database

    Jiroutová, Kateřina; Horák, Aleš; Bowler, C.; Oborník, Miroslav

    2007-01-01

    Roč. 65, č. 5 (2007), s. 496-511 ISSN 0022-2844 R&D Projects: GA AV ČR IAA500220502 Institutional research plan: CEZ:AV0Z60220518 Keywords : tryptophan synthesis * mosaic origin * diatom * Oomycetes Subject RIV: EB - Genetics ; Molecular Biology Impact factor: 3.234, year: 2007

  14. EU energy-intensive industries and emissions trading: losers becoming winners?

    Energy Technology Data Exchange (ETDEWEB)

    Wettestad, Joergen

    2008-11-15

    The EU Emissions Trading System (ETS) initially treated power producers and energy-intensive industries similarly, despite clear structural differences between these industries regarding pass through of costs and vulnerability to global competition. Hence, the energy-intensive industries could be seen as losing out in the internal distribution. In the January 2008 proposal for a reformed ETS post-2012, a differentiated system was proposed where the energy-intensive industries come out relatively much better. What is the explanation for the change taking place? Although power producers still have a dominant position in the system, the increasing consensus about windfall profits has weakened their standing. Conversely, the energy-intensive industries have become better organised and more active. This balance shift is first and foremost noticeable in several important EU-level stake holder consultation processes. Energy-intensive industries have, however, also successfully utilised the national pathway to exert influence on Brussels policy-making. Finally, growing fear of lax global climate policies and related carbon leakage has strengthened the case of these industries further. The latter dimension indicates that although energy-intensive industries have managed to reduce internal distribution anomalies, external challenges remain. (author). 9 refs

  15. Are PhDs Winners or Losers? Wage Premiums for Doctoral Degrees in Private Sector Employment

    DEFF Research Database (Denmark)

    Pedersen, Heidi Skovgaard

    2016-01-01

    Policy makers expect that increasing shares of PhDs will find employment within the private sector. However, the incentive structure for undertaking PhD education and subsequently seeking private sector employment has not been adequately assessed in the literature. This paper investigates...... to choose private sector employment immediately after award of the PhD degree....

  16. 2011 IEEE Visualization Contest winner: Visualizing unsteady vortical behavior of a centrifugal pump.

    Science.gov (United States)

    Otto, Mathias; Kuhn, Alexander; Engelke, Wito; Theisel, Holger

    2012-01-01

    In the 2011 IEEE Visualization Contest, the dataset represented a high-resolution simulation of a centrifugal pump operating below optimal speed. The goal was to find suitable visualization techniques to identify regions of rotating stall that impede the pump's effectiveness. The winning entry split analysis of the pump into three parts based on the pump's functional behavior. It then applied local and integration-based methods to communicate the unsteady flow behavior in different regions of the dataset. This research formed the basis for a comparison of common vortex extractors and more recent methods. In particular, integration-based methods (separation measures, accumulated scalar fields, particle path lines, and advection textures) are well suited to capture the complex time-dependent flow behavior. This video (http://youtu.be/oD7QuabY0oU) shows simulations of unsteady flow in a centrifugal pump.

  17. Why RCN Nurse of the Year is such an inspiring winner.

    Science.gov (United States)

    2017-05-10

    Remember the name: Melanie Davies, RCN Nurse of the Year 2017 and a truly extraordinary woman. She has transformed care for people with learning disabilities on her ward, driven through changes across her hospital and health board in south Wales, and inspired others to follow suit across the country.

  18. Cold Vs. Heat After Exercise-Is There a Clear Winner for Muscle Soreness.

    Science.gov (United States)

    Petrofsky, Jerrold S; Khowailed, Iman Akef; Lee, Haneul; Berk, Lee; Bains, Gurinder S; Akerkar, Siddhesh; Shah, Jinal; Al-Dabbak, Fuad; Laymon, Mike S

    2015-11-01

    Because of the differences in the exercise type, temperature, and timing of the use of cold and heat after exercise in different studies, there is no clear conclusion as to the efficacy of either modality on reducing delayed onset muscle soreness. One hundred subjects at similar fitness levels were examined. They accomplished leg squats for 15 minutes and heat and cold were applied after or 24 hours after exercise using ThermaCare heat or cold wraps. Measurements obtained were strength, the force to passively move the knee, analog visual pain scales, and blood myoglobin. Control subjects lost 24% strength after exercise. Subjects with heat or cold just after exercise only lost 4% strength (p < 0.01). For strength recovery, cold applied after 24 hours was better than heat at 24 hours. Heat or cold applied after exercise was significantly better to prevent elastic tissue damage (p < 0.01), whereas heat and cold immediately after exercise caused no loss in muscle myoglobin and heat or cold after 24 hours showed no less muscle damage from myoglobin than in control subjects. Myoglobin in the control and heat and cold 24-hour groups averaged 135.1% of the baseline data but averaged 106.1% of baseline in the immediate heat and cold groups. For reducing pain, control subjects showed a significant amount of pain the days after exercise. But cold immediately after exercise or 24 hours later was superior to heat in reducing pain. In conclusion, both cold and heat appear to be efficacious in reducing muscle damage after exercise.

  19. Interview with Xiaoli Wang PhD winner of CACA 2016 Young Investigator Award

    Directory of Open Access Journals (Sweden)

    Xiaoli Wang

    2016-07-01

    Full Text Available Xiaoli Wang is currently an R&D Senior Scientist in Agilent’s HPLC instrument R&D group at Agilent Technologies, Waldbronn, Germany. Prior to this, he was an R&D manager in Agilent’s CrossLab Group in the US focusing on development of novel chromatographic columns. He has a B.S. degree in Chemistry from Peking University, Beijing China and a PhD. degree in Analytical Chemistry from the University of Minnesota in 2006. He started his industrial career in the pharmaceutical industry at AstraZeneca for four years before joining Agilent Technologies in 2010. Recently, he won the prestigious 2016 Young Investigator Award from Chinese American Chromatography Association (CACA. This interview was conducted by Roland J.W. Meesters PhD, Editor-in-Chief of Journal of Applied Bioanalysis.

  20. 2011 IEEE Visualization Contest Winner: Visualizing Unsteady Vortical Behavior of a Centrifugal Pump

    KAUST Repository

    Otto, Mathias

    2012-09-01

    In the 2011 IEEE Visualization Contest, the dataset represented a high-resolution simulation of a centrifugal pump operating below optimal speed. The goal was to find suitable visualization techniques to identify regions of rotating stall that impede the pump\\'s effectiveness. The winning entry split analysis of the pump into three parts based on the pump\\'s functional behavior. It then applied local and integration-based methods to communicate the unsteady flow behavior in different regions of the dataset. This research formed the basis for a comparison of common vortex extractors and more recent methods. In particular, integration-based methods (separation measures, accumulated scalar fields, particle path lines, and advection textures) are well suited to capture the complex time-dependent flow behavior. This video (http://youtu.be/ oD7QuabY0oU) shows simulations of unsteady flow in a centrifugal pump. © 2012 IEEE.

  1. Wheatley Award 2017 Winner: How Physics Can Help Africa Transform, from a Problem to an Opportunity

    Science.gov (United States)

    Turok, Neil

    2017-01-01

    Africa represents the world's greatest untapped pool of scientific and technical talent. The African Institute for Mathematical Sciences (AIMS) is providing outstanding postgraduate training and research opportunities to gifted students across the continent. Its alumni proceed to employment in fields ranging from epidemiology to natural resource management, information technology and mathematical finance, to engineering and pure research in physics and mathematics. Many have already had a major impact in revitalising Africa's universities, in tackling major epidemics, and in raising skills levels in industry and government. AIMS has opened six centres of excellence so far, in South Africa, Senegal, Ghana, Cameroon, Tanzania, and, most recently, Rwanda, and plans to grow to a network of fifteen centres over the next decade. Its 1200 alumni are at the leading edge of Africa's transformation into a knowledge-based society.

  2. The possibilities of a reading of the legal phenomenon from religion: the methodological proposal and the example of the political theology of John Calvin

    Directory of Open Access Journals (Sweden)

    Caetano Dias Corrêa

    2017-05-01

    Full Text Available http://dx.doi.org/10.5007/2177-7055.2017v38n75p189 This paper aims to discuss and try to lay the foundations for an approach to legal phenomenon from a theoretical leather study own religions, given the diverse, and often unexplored, interfaces between law and religion. In this sense, it presents the theoretical frameworks for the proposed approach, which is worth the specificity of the categories developed within the science of religions, taking the religious phenomenon by their own religious and specific aspects, using then John Calvin’s political theology as initial sample analysis.

  3. Biodegradation of endosulfan by mixed bacteria culture strains of ...

    African Journals Online (AJOL)

    Biodegradation of endosulfan by mixed bacteria culture strains of Pseudomonas aeruginosa and Staphylococcus aureus. Nsidibeabasi Calvin Nwokem, Calvin Onyedika Nwokem, Casmir Emmanuel Gimba, Beatrice Nkiruka Iwuala ...

  4. ASB clinical biomechanics award winner 2016: Assessment of gaze stability within 24-48hours post-concussion.

    Science.gov (United States)

    Murray, Nicholas G; D'Amico, Nathan R; Powell, Douglas; Mormile, Megan E; Grimes, Katelyn E; Munkasy, Barry A; Gore, Russell K; Reed-Jones, Rebecca J

    2017-05-01

    Approximately 90% of athletes with concussion experience a certain degree of visual system dysfunction immediately post-concussion. Of these abnormalities, gaze stability deficits are denoted as among the most common. Little research quantitatively explores these variables post-concussion. As such, the purpose of this study was to investigate and compare gaze stability between a control group of healthy non-injured athletes and a group of athletes with concussions 24-48hours post-injury. Ten collegiate NCAA Division I athletes with concussions and ten healthy control collegiate athletes completed two trials of a sport-like antisaccade postural control task, the Wii Fit Soccer Heading Game. During play all participants were instructed to minimize gaze deviations away from a central fixed area. Athletes with concussions were assessed within 24-48 post-concussion while healthy control data were collected during pre-season athletic screening. Raw ocular point of gaze coordinates were tracked with a monocular eye tracking device (240Hz) and motion capture during the postural task to determine the instantaneous gaze coordinates. This data was exported and analyzed using a custom algorithm. Independent t-tests analyzed gaze resultant distance, prosaccade errors, mean vertical velocity, and mean horizontal velocity. Athletes with concussions had significantly greater gaze resultant distance (p=0.006), prosaccade errors (pconcussions had less control of gaze during play of the Wii Fit Soccer Heading Game. This could indicate a gaze stability deficit via potentially reduced cortical inhibition that is present within 24-48hours post-concussion. Copyright © 2017 Elsevier Ltd. All rights reserved.

  5. 2000 Volvo Award winner in biomechanical studies: Monitoring in vivo implant loads with a telemeterized internal spinal fixation device.

    Science.gov (United States)

    Rohlmann, A; Graichen, F; Weber, U; Bergmann, G

    2000-12-01

    Implant loads were measured in 10 patients using telemeterized internal spinal fixation devices. To determine the postoperative temporal course of implant loads. Little information exists regarding the temporal course of loads on internal spinal fixation devices. The telemeterized internal spinal fixator allows the measurement of three force components and three moments acting in the fixator. Implant loads were determined in up to 20 measuring sessions for different activities, including walking, standing, sitting, lying in the supine position, and lifting an extended leg while in the supine position. Implant loads often increased shortly after anterior interbody fusion was performed. Several patients retained the same high level even after fusion had taken place. This explains the reason why screw breakage sometimes occurs more than half a year after implantation. The time of fusion could not be pinpointed from the loading curves. The results show that fixators may be highly loaded even after fusion has occurred. A flexion bending moment acts on the implant even with the body in a relaxed lying position. This means that already shortly after the anterior procedure, the shape of the spine is not neutral and unloaded, but slightly deformed, which loads the fixators. Pedicle screw breakage more than half a year after insertion does not prove that anterior interbody fusion has not occurred.

  6. 1997 Volvo Award winner in biomechanical studies. Kinematic behavior of the porcine lumbar spine: a chronic lesion model.

    Science.gov (United States)

    Kaigle, A M; Holm, S H; Hansson, T H

    1997-12-15

    Experimental models of intervertebral disc and facet joint degeneration were created in vivo in the porcine lumbar spine for studying spinal kinematics, using a dynamic technique. To quantify the changes in spinal kinematics and the stabilizing capacity of the lumbar musculature caused by chronic lesions in the intervertebral disc and facet joints. Segmental kinematics are detrimentally altered by acute injury to passive structures of the motion segment. However, stimulation of the surrounding musculature adds stability to the motion segment. The in vivo kinematics of a degenerated lumbar motion segment and the stabilizing function of the surrounding musculature have not been quantified dynamically. Forty-four pigs were used in six chronic lesions models: sham, disc anulus, disc nucleus, facet capsule, facet joint slit, and facet joint wedge. Three months after injury, an instrumented linkage was used to measure continuously the sagittal kinematics of the L3-L4 motion segment during flexion-extension, with and without stimulation of the lumbar paraspinal musculature. Flexion-extension end point and maximum ranges of motion, and hysteresis were analyzed. Significant alterations in the kinematics caused by chronic lesions were observed, particularly when using the maximum range of motion and when comparing changes in axial translation. Muscular stimulation reduced the hysteresis in the sham, facet capsule, and disc nucleus groups; however, increased hysteresis was observed in the remaining lesion groups. The kinematic behavior of motion segments with chronic lesions was established. The maximum range of motion, which must be measured using a dynamic technique, was a more sensitive parameter for identifying changes in segmental kinematics caused by chronic lesions than was the end range of motion. The lumbar musculature was less efficient overall in stabilizing the motion segment, possibly because of altered mechanisms in the neuromuscular feedback system.

  7. 1997 Volvo Award winner in basic science studies. Immunohistologic markers for age-related changes of human lumbar intervertebral discs.

    Science.gov (United States)

    Nerlich, A G; Schleicher, E D; Boos, N

    1997-12-15

    The authors performed a correlative macroscopic, histologic, and immunohistochemical investigation on human lumbar intervertebral discs using complete motion segment slices, including all age groups and stages of degeneration. To identify markers for age-related changes of human lumbar intervertebral discs. In particular, to investigate changes in the distribution pattern of collagen Types I, II, III, IV, V, VI, IX, and X. In addition, to study posttranslational protein modification by the immunolocalization of N-(carboxylmethyl)lysine (CML), which is regarded as a biomarker for oxidative stress. Data on a correlation of age-related changes in disc morphology and disc matrix composition is sparse. So far, no comprehensive analysis considered a correlation of macroscopic, histologic, and biochemical age-related alterations using complete sections of intervertebral discs (i.e., including nucleus pulposus, anulus fibrosus, endplates, and vertebral bodies). In addition, there is need for specific markers for these disc changes to allow for a better correlation with disc function. After photodocumentation of the macroscopic appearance, 229 sagittal lumbar motion segments obtained from 47 individuals (fetal to 86 years) during routine autopsy were processed for histologic and immunohistochemical analysis. All slices were investigated for histologic alterations of disc degeneration. A randomly selected subset of these specimens (n = 45) was used for a correlative analysis of interstitial collagens and molecular modifications of matrix proteins. The presence of CML-modification of extracellular matrix proteins, mainly collagen, was observed first in the nucleus pulposus of a 13-year-old individual and increased significantly with age. In elderly people, both the nucleus pulposus and the anulus fibrosus showed extensive CML deposition. This CML deposition was accentuated in areas of macroscopic and histologic disc degeneration. After the occurrence of CML in the nucleus pulposus, we found a change in the collagen type pattern. An initial increase in nuclear collagen Types II, III, and VI staining was followed by a loss of collagen Type II, the occurrence of collagen Type I, and the persistence of high collagen Type III and VI levels, which were finally decreased again. The nuclear chondrocytes revealed significant changes in their immediate pericellular matrix, indicating phenotypic changes. Thus, exclusively in the nucleus pulposus of adolescents and young adults a significant proportion of cells positively stained for the basement membrane collagen Type IV. Collagen Type X was expressed by nuclear chondrocytes at a higher age and was associated with advanced degenerative disc alterations. The authors present the first study in which age-related changes are correlated on a macroscopic, histologic, and molecular level using complete sections of lumbar motion segments. They reconfirm the notion that disc degeneration starts as early as in the second decade of life. Therefore, only early prevention of disc damage may inhibit disc degeneration and its sequelae. Phenotypic alterations of nuclear chondrocytes as monitored by collagen Type IV in young adults with minor lesions and collagen Type X in advanced lesions indicate distinct cellular reactions, possibly as a reaction to enhanced oxidative stress. The degree of this oxidative stress is reflected by the CML-staining pattern which, in turn, indicates that the disc undergoes an accumulative stress, possibly leading to altered properties of the collagen fibrils and, thereby, tissue destruction. The deposition of CML proved to be the best marker for ongoing age-related changes in the intervertebral disc.

  8. 2000 Volvo Award winner in clinical studies: Lumbar high-intensity zone and discography in subjects without low back problems.

    Science.gov (United States)

    Carragee, E J; Paragioudakis, S J; Khurana, S

    2000-12-01

    A prospective observational study of patients with low back pain and those without was performed. To investigate the prevalence and significance of a high-intensity zone in a group of patients asymptomatic for low back pain, but who had known risk factors for lumbar disc degeneration. This asymptomatic group was compared with a symptomatic group of patients with respect to the presence of anular high-intensity zone and the pain response with discography. Some authors have estimated the prevalence of a high-intensity zone in a group of symptomatic patients to be 86%. They have reported a strong correlation between a high-intensity zone and positive discography in patients with low back pain. Other investigators have reported evidence either supporting or discounting these findings. Patients with low back pain and those without underwent physical examination, psychometric testing, plain radiograph, magnetic resonance imaging, and discography. The presence of a high-intensity zone, anular disruption, and positive discographic pain then were compared between the two groups. There were strict inclusion criteria for both groups. A total of 109 discs in 42 patients were evaluated in the symptomatic group and compared with 143 discs in 54 patients in the asymptomatic group. The presence of a high-intensity zone was determined by a standardized criteria on T2-weighted magnetic resonance images. Psychometric testing also was administered to each patient before discography. Standard discography was performed on all the patients, and the pain response was recorded using a visual analog scale according to the Walsh et al criteria. The prevalence of a high-intensity zone in the patient populations was 59% in the symptomatic group and 24% in the asymptomatic group. In the symptomatic group, 33 (30.2%) of 109 discs were found to have a high-intensity zone. In the asymptomatic group, 13 of 143 discs were found to have a high-intensity zone. In the symptomatic group, 72.7% of the discs with a high-intensity zone were positive on discography, whereas 38.2% of the discs without a high-intensity zone were positive. In the asymptomatic group, 69.2% of the discs with a high-intensity zone were positive on discography, whereas 10% of the discs without a high-intensity zone were positive. In the patients with normal psychometric testing, 50% of the discs with a high-intensity zone were positive on discography, as compared with 100% positive discography results in patients with abnormal psychometric testing or chronic pain. The presence of a high-intensity zone does not reliably indicate the presence of symptomatic internal disc disruption. Although higher in symptomatic patients, the prevalence of a high-intensity zone in asymptomatic individuals with degenerative disc disease (25%) is too high for meaningful clinical use. When injected during discography, the same percentage of asymptomatic and symptomatic discs with a high-intensity zone were shown to be painful.

  9. 1980 Volvo award winner in basic science. Nutritional pathways of the intervertebral disc. An experimental study using hydrogen washout technique.

    Science.gov (United States)

    Ogata, K; Whiteside, L A

    1981-01-01

    The pathways of material transfer to the intervertebral disc were studied in adult dogs by measuring diffusion of hydrogen molecules in the nucleus pulposus before and after disruption of the route through the annulus fibrosus and before and after disruption of the end-plate route. The interfaces was only in the central two-thirds of one side, caused significantly greater decrease in the rate of hydrogen washout than the disruption of the annulus route. Histologically, the bone-cartilage interface was frequently perforated by marrow cavity and vascular buds. These findings suggest that the end-plate route is a major pathway for material transfer to the intervertebral disc.

  10. Dimensions of Conventionality and Innovation in Film: The Cultural Classification of Blockbusters, Award Winners, and Critics' Favourites

    NARCIS (Netherlands)

    A. Kersten (Annemarie); M.N.M. Verboord (Marc)

    2014-01-01

    textabstractToday's complex film world seems to upset the dual structure corresponding with Bourdieu's categorization of 'restricted' and 'large-scale' fields of cultural production. This article examines how movies in French, Dutch, American and British film fields are classified in terms of

  11. "Anyone Can Make It, but There Can Only Be One Winner": Modelling Neoliberal Learning and Work on Reality Television

    Science.gov (United States)

    Windle, Joel

    2010-01-01

    This article investigates how reality television talent-quest formats model the normative neoliberal worker and learner--roles which are increasingly drawn together. In the age of "life-long learning" and shifting employment demands, new models of the supple, adaptable and willing learner are increasingly important both to meeting…

  12. Girls in Technology Essay Contest Winner Spends a Day in the Life of a Scientist | FNLCR Staging

    Science.gov (United States)

    Sixteen-year-old Celina Paudel solidified her career interest in biomedical engineering after winning a scholarship through the national Girls in Technology (GIT) program. Then, thanks to Rachel Bagni, she got to see what it really means to be a scie

  13. Winners and losers in transition: preferences for redistribution and nostalgia for communism in Eastern Europe / Adam Okulicz- Kozaryn

    Index Scriptorium Estoniae

    Okulicz- Kozaryn, Adam

    2014-01-01

    Artikli teema on üleminekuperioodi võitjad ja kaotajad Ida-Euroopas (sh. Eesti), täpsemalt käsitletakse nostalgiat kommunismi järele. Andmed pärinevad uurimusest „Demokraatia konsolideerumine Kesk- ja Ida-Euroopas 1990-2001”.

  14. Marie and Irene Curie. The first female Nobel Prize winners; Marie en IreneCurie. De eerste vrouwelijke Nobelprijswinnaars

    Energy Technology Data Exchange (ETDEWEB)

    Noordenbos, G. [Joke Smit Instituut voor Vrouwenstudies, Universiteit Leiden, Leiden (Netherlands)

    2003-07-01

    Marie Curie was awarded the Nobel Prize in 1903 and in 1911. Also her daughter, Irene Joliot-Curie, received a Nobel Prize for science in 1935. In this book an overview is given of the academic world at that time: limited access to universities for women, the carriers of both women in physics and their pioneering research and discoveries, the refusal of Marie Curie by the French Academy of Sciences, the awarding of the Nobel Prize and the assignment of Irene Joliot-Curie as the first female minister in France, the impact of the two World Wars, their married and private lives and the constant smear campaign of the press against both women. The lives and works of both women are hold against the light of the present position of women in physical sciences. [Dutch] In 1903, precies honderd jaar geleden, ontving Marie Curie als eerste vrouw de Nobelprijs voor de Wetenschap, gevolgd door een tweede Nobelprijs in 1911. Ook haar dochter Irene Joliot-Curie kreeg de Nobelprijs voor de wetenschap in 1935. Marie and Irene Curie schetst een breed beeld van de academische wereld waarin beide vrouwen zich bewogen: de beperkte toegang van vrouwen tot de universiteit, hun carrisres in de natuurkunde en baanbrekende ontdekkingen, de afwijzing van Marie door de Franse Academie des Sciences, de toekenning van de Nobelprijs en de benoeming van Irene als eerste vrouwelijke minister in Frankrijk, de invloed van de twee Wereldoorlogen, hun huwelijks- en priveleven en de niet aflatende hetze van de pers tegen beiden. In de door mannen gedomineerde wereld van de natuurwetenschappen liep de uitzonderingspositie van beide vrouwen als rode draad door hun curieuze levens. Het leven en werk van de Curies wordt geactualiseerd door deze tegen het licht te houden van de huidige positie van vrouwen in de natuurwetenschappen. Het bereiken van de top van de wetenschap door vrouwen blijkt nog steeds uitzonderlijk.

  15. Glucocorticoid excess and the developmental origins of disease: two decades of testing the hypothesis--2012 Curt Richter Award Winner.

    Science.gov (United States)

    Reynolds, Rebecca M

    2013-01-01

    Low birthweight, a marker of an adverse in utero environment, is associated with cardiometabolic disease and brain disorders in adulthood. The adaptive changes made by the fetus in response to the intra-uterine environment result in permanent changes in physiology, structure and metabolism, a phenomenon termed early life programming. One of the key hypotheses to explain programming, namely over exposure of the developing fetus to glucocorticoids, was proposed nearly two decades ago, following the observation that the fetus was protected from high glucocorticoid levels in the mother by the actions of the placental barrier enzyme, 11β-hydroxysteroid dehydrogenase, which converts active glucocorticoids into inactive products. Numerous mechanistic studies in animal models have been carried out to test this hypothesis using manipulations to increase maternal glucocorticoids. Overall, these have resulted in offspring of lower birthweight, with an activated hypothalamic-pituitary-adrenal (HPA) axis and an adverse metabolic profile and behavioural phenotype in adulthood. Altered glucocorticoid activity or action is a good candidate mechanism in humans to link low birthweight with cardiometabolic and brain disorders. We have carried out detailed studies in men and women showing that high levels of endogenous glucocorticoids, or treatment with exogenous glucocorticoids, is associated with an adverse metabolic profile, increased cardiovascular disease and altered mood and cognitive decline. Our laboratory carried out the first translational studies in humans to test the glucocorticoid hypothesis, firstly demonstrating in studies of adult men and women, that low birthweight was associated with high fasting cortisol levels. We went on to dissect the mechanisms underlying the high fasting cortisol, demonstrating activation of the HPA axis, with increased cortisol responses to stimulation with exogenous adrenocorticotrophin hormone, lack of habituation to the stress of venepuncture, and increased cortisol responses to psychosocial stress. We have developed new dynamic tests to dissect the mechanisms regulating HPA axis central negative feedback sensitivity in humans, and demonstrated that this may be altered in obesity, one component of the metabolic syndrome. There are now studies in humans demonstrating that high circulating levels of maternal cortisol during pregnancy correlate negatively with birthweight, suggesting that excess glucocorticoids can by-pass the placental barrier. Deficiencies in the barrier enzyme, potentially increasing fetal glucocorticoid exposure, can also arise in association with maternal stress, malnutrition and disease, and can be inhibited by consumption of liquorice, which contains glycyrrhizin, an HSD inhibitor. Importantly, studies in humans have now demonstrated that high maternal cortisol in pregnancy and/or inhibition of HSD2 are associated with programmed outcomes in childhood including higher blood pressure, behavioural disorders as well as altered brain structure. We are investigating this further, using novel magnetic resonance imaging techniques to study the developing fetal brain in utero. The translational studies in support of the glucocorticoid hypothesis, and demonstrating that glucocorticoids are both mediators and targets of programming, are exciting and raise the question of whether this information can be used to identify those individuals most at risk of later life disease. In a recent study we showed that alterations in DNA methylation at genes important in regulating cortisol levels, tissue glucocorticoid action, blood pressure and fetal growth, are present in adulthood in association with both early life parameters and cardiometabolic risk factors. These preliminary data add to the limited literature in humans indicating a persisting epigenetic link between early life events and subsequent disease risk. Such findings open novel avenues for further exploration of the contribution of glucocorticoids to later life disease. Copyright © 2012 Elsevier Ltd. All rights reserved.

  16. The Redistributive Impact of Restrictive Measures on EU Members: Winners and Losers from Imposing Sanctions on Russia

    NARCIS (Netherlands)

    Giumelli, Francesco

    2017-01-01

    EU sanctions on Russia created concerns among its members. It is well known that sanctions impose a cost on their targets as well as on the senders, as lamented by European governments, but the costs of EU sanctions on its members have not been fully explored. This article intends to fill this gap

  17. Fine-scale ecological and economic assessment of climate change on olive in the Mediterranean Basin reveals winners and losers

    OpenAIRE

    Ponti, Luigi; Gutierrez, Andrew Paul; Ruti, Paolo Michele; Dell’Aquila, Alessandro

    2014-01-01

    Inability to determine reliably the direction and magnitude of change in natural and agro-ecosystems due to climate change poses considerable challenge to their management. Olive is an ancient ubiquitous crop having considerable ecological and socioeconomic importance in the Mediterranean Basin. We assess the ecological and economic impact of projected 1.8 °C climate warming on olive and its obligate pest, the olive fly. This level of climate warming will have varying impact on olive yield an...

  18. 2016 Writing Contest graduate Winner: Cardiovascular Disease Training for Community Health Workers Serving Native Hawaiians and Other Pacific Peoples.

    Science.gov (United States)

    Moleta, Chace DI; Look, Mele A; Trask-Batti, Mililani K; Mabellos, Tricia; Mau, Marjorie L

    2017-07-01

    To help community health workers (CHW) meet increased demand for their services, it is essential to have data supported strategies for approaches to their training and capacity development. The objective of this paper is to report on the development, implementation, and evaluation of "Heart 101," a cardiovascular disease (CVD) training program, conducted among CHW in Hawai'i who serve Native Hawaiians and other Pacific Peoples (NHPP). Principles from Community-Based Participatory Research provided a framework to develop and implement the 5-hour training curriculum. Developers incorporated teaching strategies shown to be effective among learners that represent the majority of CHW, and included principles of adult learning theory and culture-based education. Training participants completed pre-, post-, and 6-months post-training knowledge tests, as well as demographic and participant satisfaction surveys. Data analysis based on pre- and post-training knowledge tests (n=30) indicated that Heart 101 significantly increased CVD knowledge by 32% (P < .001, t test). Long-term CVD competency measured at six-months post-training (n = 20) was also shown to be significant (P < .001, t test). Analysis of knowledge by subtopic suggested CHW strengths in clinical aspects of CVD and weaknesses in medical terminology and basic science aspects. These results, along with positive participant satisfaction, suggest that a culturally relevant and interactive course is a strong approach for CVD information dissemination to CHW serving NHPP communities, and provides insight on potential areas for special focus in their training. The demonstrated success of Heart 101 has positive implications for the standardization of CHW education and for their professional development.

  19. Bio-inspired feedback-circuit implementation of discrete, free energy optimizing, winner-take-all computations.

    Science.gov (United States)

    Genewein, Tim; Braun, Daniel A

    2016-06-01

    Bayesian inference and bounded rational decision-making require the accumulation of evidence or utility, respectively, to transform a prior belief or strategy into a posterior probability distribution over hypotheses or actions. Crucially, this process cannot be simply realized by independent integrators, since the different hypotheses and actions also compete with each other. In continuous time, this competitive integration process can be described by a special case of the replicator equation. Here we investigate simple analog electric circuits that implement the underlying differential equation under the constraint that we only permit a limited set of building blocks that we regard as biologically interpretable, such as capacitors, resistors, voltage-dependent conductances and voltage- or current-controlled current and voltage sources. The appeal of these circuits is that they intrinsically perform normalization without requiring an explicit divisive normalization. However, even in idealized simulations, we find that these circuits are very sensitive to internal noise as they accumulate error over time. We discuss in how far neural circuits could implement these operations that might provide a generic competitive principle underlying both perception and action.

  20. And the winner is…. The male academy oder: Die ungleichen Auswirkungen universitärer Prekarität

    Directory of Open Access Journals (Sweden)

    Annekathrin Müller

    2016-11-01

    Full Text Available Der vorliegende Essay beleuchtet die ungleichen Auswirkungen von prekären Arbeitsbedingungen an deutschen Universitäten. Dabei vertreten wir die These, dass diese ganz unmittelbar zur Reproduktion sozialer Ungleichheit innerhalb des wissenschaftlichen Feldes beitragen, insofern Frauen und andere Menschen, die weniger privilegiert sind als weiße Cis-Männer mit bildungsbürgerlichem Hintergrund, die akademische Laufbahn in der PostDoc-Phase eher verlassen. Wir plädieren nicht nur für bessere Arbeitsbedingungen – weniger Befristungen, einen Abbau feudaler Strukturen, mehr Dauerstellen, und eine „kurze Vollzeit“ –, die Aufrechterhaltung und den Ausbau von Gleichstellungsmaßnahmen, sondern auch für eine Wissenschaftskultur, die sich vom männlichen Geniemythos abwendet, nicht mehr auf permanente Entgrenzung setzt und kollektive Prozesse in der Produktion wissenschaftlicher Erkenntnisse in Rechnung stellt.

  1. Visual Scanning Training, Limb Activation Treatment, and Prism Adaptation for rehabilitating left neglect: Who is the winner?

    Directory of Open Access Journals (Sweden)

    Konstantinos ePriftis

    2013-07-01

    Full Text Available We compared, for the first time, the overall and differential effects of three of the most widely used left neglect (LN treatments: Visual Scanning Training (VST, Limb Activation Treatment (LAT, and Prism Adaptation (PA. Thirty-three LN patients were assigned in quasi-random order to the three groups (VST, LAT, or PA. Each patient received only one type of treatment. LN patients’ performance on everyday life tasks was assessed four times (over a period of six weeks: A1 and A2 (i.e., the two pre-treatment assessments; A3 and A4 (i.e., the two post-treatment assessments. LN patients in each of the three treatment conditions were treated for the same number of sessions (i.e., 20. The results showed that improvements were present in the majority of the tests assessing the peripersonal space in everyday life activities. Our findings were independent of unspecific factors and lasted for at least two weeks following the end of the treatments. There were no interactions, however, between LN treatments and assessments. We suggest that all three treatments can be considered as valid rehabilitation interventions for LN and could be employed for ameliorating LN signs.

  2. “And the winner is…”: Hierarchies of language competence and fashion sense in Tanzanian beauty pageants

    OpenAIRE

    Billings, Sabrina

    2011-01-01

    This paper discusses how successful Tanzanian beauty contestants mark themselves as educated sophisticates through clusters of semiotic materials. At lower-level and provincial competitions, contestants’ ability to speak ‘pure,’ if non-fluent and non-standard, English helps them achieve victory. This register is coupled with local, often outlandish, interpretations of international fashions and hairstyles. Yet in the capital city, and especially at the national competition, winning contesta...

  3. McJimsey Award Winner: Ideologies of the Shri Meenakshi Goushala: Hindu and Jain Motivations for a Madurai Cow Home

    Directory of Open Access Journals (Sweden)

    Brett Evans

    2013-04-01

    Full Text Available This essay describes and analyzes the motivations underlying the creation and current organization of a recently constructed 'goshala '(cow home in the south Indian city of Madurai.  Drawing on ethnographic fieldwork carried out in 2012, I highlight the divergent visions of the 'goshala'’s purpose and future that were articulated by the institution’s Hindu and Jain members.  Interviews and informal conversations with participants indicate that many individuals conceptualize only one “authentic” tradition of animal homes.  However, within Madurai’s 'goshala 'and likely many others like it, these stakeholders referred to distinctly different traditions.  I argue that Hindu and Jain understandings of 'ahimsa '(nonviolence and the cow vary significantly, and this strongly affects individual expectations of the mission of animal homes.  Utilizing Hobsbawm and Ranger’s framework (1983, I note that the many “invented traditions” of animal homes may be difficult to accommodate within one institution, especially one with a religiously diverse membership.  I further suggest that transparent discussions which clearly indicate an animal home’s goals and mission are necessary and that the outcomes of these discussions should be effectively communicated to the wider community supporting the institution.

  4. 2016 Arte Poster Competition First Place Winner: Circadian Rhythm and UV-Induced Skin Damage: An In Vivo Study.

    Science.gov (United States)

    Guan, Linna; Suggs, Amanda; Ahsanuddin, Sayeeda; Tarrillion, Madeline; Selph, Jacqueline; Lam, Minh; Baron, Elma

    2016-09-01

    Exposure of the skin to ultraviolet (UV) irradiation causes many detrimental effects through mechanisms related to oxidative stress and DNA damage. Excessive oxidative stress can cause apoptosis and cellular dysfunction of epidermal cells leading to cellular senescence and connective tissue degradation. Direct and indirect damage to DNA predisposes the skin to cancer formation. Chronic UV exposure also leads to skin aging manifested as wrinkling, loss of skin tone, and decreased resilience. Fortunately, human skin has several natural mechanisms for combating UV-induced damage. The mechanisms operate on a diurnal rhythm, a cycle that repeats approximately every 24 hours. It is known that the circadian rhythm is involved in many skin physiologic processes, including water regulation and epidermal stem cell function. This study evaluated whether UV damage and the skin's natural mechanisms of inflammation and repair are also affected by circadian rhythm. We looked at UV-induced erythema on seven human subjects irradiated with simulated solar radiation in the morning (at 08:00 h) versus in the afternoon (at 16:00 h). Our data suggest that the same dose of UV radiation induces significantly more inflammation in the morning than in the afternoon. Changes in protein expression relevant to DNA damage, such as xeroderma pigmentosum, complementation group A (XPA), and cyclobutane pyrimidine dimers (CPD) from skin biopsies correlated with our clinical results. Both XPA and CPD levels were higher after the morning UV exposure compared with the afternoon exposure. J Drugs Dermatol. 2016;15(9):1124-1130.

  5. 2015 Arte Poster Competition First Place Winner: Assessing the Correlation Between Patient Anxiety and Satisfaction for Mohs Surgery.

    Science.gov (United States)

    Locke, Maren C; Wilkerson, Eric C; Mistur, Rachel L; Nisar, Mahrukh; Love, W Elliot

    2015-09-01

    Skin cancer and the surgical treatment thereof have the potential to be sources of great anxiety for patients. Examination of patient satisfaction, anxiety, and contributing factors has the potential to provide information surgeons can use to implement practices that have an impact on patient anxiety and satisfaction regarding dermatologic surgery. This study used a prospective interview to catalog patients' anxiety and experiences before and during the surgical process. Our results indicate that several pre- and perioperative factors have the potential to decrease a patient's overall anxiety. Notably, 33% of surgical patients reported a decrease in anxiety from the time of diagnosis until the day of surgery. Factors that contributed to this included a call discussing the diagnosis and what to expect on the day of surgery as well as reading written material or searching the internet for more information regarding the procedure. Furthermore, a call from the physician compared to a call from a nurse or other team member showed a greater effect on decreasing anxiety. During the surgical procedure, our results highlight several factors that can decrease a patient's anxiety. Most notably, eating, watching TV, bringing a guest, and engaging in small talk with surgeon and staff during the procedure subjectively decreased patients' anxiety. In summary, our results suggest that patients respond to a variety of factors to reduce anxiety and that each patient derives relief from anxiety in different manners. Therefore, offering a spectrum of comforting or distracting activities during the Mohs procedure is ideal and may reduce the need for pharmacologic anxiolytics.

  6. Differences in performance indicators among winners and losers of group a of the spanish basketball amateur league (EBA

    Directory of Open Access Journals (Sweden)

    Isabel Parejo

    2013-01-01

    Full Text Available El objetivo de este estudio es identificar las diferencias existentes en los indicadores de rendimiento entre equipos ganadores y perdedores, en función del tipo de partido, en el Grupo A de la Liga Española de Baloncesto Amateur. La muestra del estudio estuvo constituida por 231 partidos (N = 462 casos disputados durante la temporada 2005/2006 por los equipos del Grupo A durante la Fase Regular de la Liga EBA (Española de Baloncesto Amateur. Las variables del estudio fueron los indicadores de rendimiento y las variables secundarias, posesiones de balón y coeficientes de eficacia ofensiva y defensiva. El análisis inferencial entre ganadores y perdedores mostró que existían diferencias significativas en varios de los indicadores de rendimiento y los coeficientes de eficacia en los tres tipos de partido, aumentando el número de indicadores que diferencian a medida que se desequilibran los encuentros. En los partidos equilibrados son los lanzamientos de 2 puntos fallados, los tiros libres anotados, los rebotes defensivos, las asistencias y las faltas personales, así como los coeficientes de eficacia, los que diferencian entre ganadores y perdedores. En los partidos desequilibrados se añaden los lanzamientos de campo anotados, las pérdidas y los tapones efectuados. En el caso de los partidos muy desequilibrados casi todos los indicadores de rendimiento excepto las recuperaciones, los rebotes ofensivos y los lanzamientos de 3 puntos fallados diferencian a los ganadores de los perdedores. Se pone de manifiesto que existen un mayor número de indicadores de rendimiento de media que diferencian a los equipos ganadores de los perdedores con respecto a otras ligas más profesionales, por lo que se puede afirmar que existe mayor heterogeneidad entre el nivel de los equipos que conforman este tipo de ligas amateur.

  7. Mechanisms of Bactericide Resistance in Phytopathogenic Bacteria(Abstracts of the Research by the Winners of the Young Scientist Award)

    OpenAIRE

    Masami, NAKAJIMA; School of Agriculture, Ibaraki University

    2002-01-01

    Bactericides containing copper and streptomycin have been widely used to control bacterial plant diseases. However, the efficacy of copper and streptomycin have been reduced by the development of copper- and streptomycin-resistant bacterial strains. Understanding the mechanism of resistance is necessary for the prevention and management of resistance. In this study, the mechanisms of copper and streptomycin resistance in Pseudomonas syringae pv. actinidiae were analyzed.

  8. Winners, Socially Displaced and Cinderellas: Representations of Race and Social Climbing in the Second Half of the Twentieth Century

    Directory of Open Access Journals (Sweden)

    Pietro Pisano

    2014-01-01

    Full Text Available From the study of articles published in Colombian magazines (particularly Cromos magazine in the second half of the twentieth century, this article proposes the analysis of some representations about upward mobility of black people. Consideration is given to the stories of some characters at different times: the judge Jose Antonio Camacho, the boxer Kid Pambelé, the model Laura Mosquera and the pianist Teresa Gómez. Although they emerged in different professional contexts, narratives about their paths have in common the emphasis on how the class representations articulated with the race and gender ones and were used to show the difficulty for a black person to be inserted in a social context different from the popular sectors, showing both their alleged incompatibility with the values of the middle class as well as the inability to fully integrate into a society dominated by whites.

  9. Calvin et l’Humanisme, «Actes du Symposium d’Amiens et Lille III: 25-26 novembre 2009», organisé par Bénédicte Boudou et Anne-Pascale Pouey-Mounou

    OpenAIRE

    Mastroianni, Michele

    2016-01-01

    Nel moltiplicarsi delle manifestazioni per il centenario calviniano, il Convegno di Amiens e Lille, presenta un interesse particolare per gli studiosi delle discipline umanistiche per avere esaminato la relazione fra Umanesimo e Calvinismo anche al di fuori del campo più propriamente teologico. Difatti, le indagini vertono su «ciò che, nel rapporto di Calvino con la scrittura (e con la Scrittura), come pure con gli umanisti contemporanei, testimonia sia una comprensione umanistica dei testi e...

  10. Biodegradation of Endosulfan by Mixed Bacteria Culture Strains

    African Journals Online (AJOL)

    Nwokem et al.

    Aeruginosa and Staphylococcus Aureus. BIODEGRADATION OF ENDOSULFAN BY MIXED BACTERIA. CULTURE STRAINS OF PSEUDOMONAS AERUGINOSA AND. STAPHYLOCOCCUS AUREUS. Nwokem Nsidibeabasi Calvin1*, Nwokem Calvin Onyedika.2 , Gimba Casmir Emmanuel1 and Iwuala Beatrice Nkiruka1.

  11. Verso, recto, get down to the Vilnius Book Fair / Milda Seputyte

    Index Scriptorium Estoniae

    Seputyte, Milda

    2005-01-01

    Leedus toimuvast raamatumessist, kus osalevad ka kirjanikud teistest riikidest: Niccolo Ammaniti Itaaliast, Jens Christian Grondahl Taanist, Colleen McCullough Austraaliast, Melvin Burgess Suur Britanniast jt.

  12. 310---11 Dec 2009 [ Final version].indd

    African Journals Online (AJOL)

    2009-12-11

    Dec 11, 2009 ... of Calvin's pneumatology, in addition to the already mentioned argument of the individual's concern for ... Gospel and a missionary vision. Calvin stressed two aspects in his pneumatology: (i) The work of the ..... When referring to Paul in the Epistle to the Colossians, Calvin emphasises (Institutes, Book IV, ...

  13. Kategese, kategismusse en die belydenis van geloof in Geneve in ...

    African Journals Online (AJOL)

    In this article the catechetical instruction of the children of the faithful, that Calvin introduced in Geneva, is de scribed. In the first place attention is given to the cate chetical instruction as Calvin and Farel practised it during the years 1536-1538. On his return to Geneva in. 1541 Calvin reorganised the catechetical instruction.

  14. Carbon Tetrachloride Increases Intracellular Calcium in Rat Liver and Hepatocyte Cultures

    Science.gov (United States)

    1986-05-12

    protected from CC14 ’s effects. Scavengers of free radicals and antioxidants such as alpha-tocopherol ( vitamin E), diphenyl-p-phenylenediamine, and...A. L. Melvin, P. Shaw, W. T. Melvin, and M. D. Burke. (1985) Studies on the Maintenance of Cytochrome& P-450 and b5 Monooxygenases and Cytochrome

  15. A Silver Medal Winner at the 13th World Wu Shu Championship 2015 17 Months After Selective Thoracic Fusion for Adolescent Idiopathic Scoliosis: A Case Report.

    Science.gov (United States)

    Chan, Chris Yin Wei; Aziz, Izzuddin; Chai, Fong Wei; Kwan, Mun Keong

    2017-02-15

    Case report. To report the successful rehabilitation and the training progress of an elite high performance martial art exponent after selective thoracic fusion for Adolescent Idiopathic Scoliosis (AIS). Posterior spinal fusion for AIS will result in loss of spinal flexibility. The process of rehabilitation after posterior spinal fusion for AIS remains controversial and there are few reports of return to elite sports performance after posterior spinal fusion for AIS. We report a case of a 25-year-old lady who was a national Wu Shu exponent. She was a Taolu (Exhibition) exponent. She underwent Selective Thoracic Fusion (T4 to T12) using alternate level pedicle screw placement augmented with autogenous local bone graft in June 2014. She commenced her training at 3-month postsurgery and the intensity of her training was increased after 6 months postsurgery. We followed her up to 2 years postsurgery and showed no instrumentation failure or lost of correction. After selective thoracic fusion, her training process consisted of mainly speed training, core strengthening, limb strengthening, and flexibility exercises. At 17 months of postoperation, she participated in 13th World Wu Shu Championship 2015 and won the silver medal. Return to elite high-performance martial arts sports was possible after selective thoracic fusion for AIS. The accelerated and intensive training regime did not lead to any instrumentation failure and complications. 2.

  16. Effects of cortisol on cognition in major depressive disorder, posttraumatic stress disorder and borderline personality disorder - 2014 Curt Richter Award Winner.

    Science.gov (United States)

    Wingenfeld, Katja; Wolf, Oliver T

    2015-01-01

    Stress hormones influence a wide range of cognitive functions, including memory performance and executive function. It is well established that glucocorticoids enhance memory consolidation but impair memory retrieval. While most of the effects have been attributed to glucocorticoid receptors (GR), the importance of mineralocorticoid receptors (MR) has been also emphasized. Dysfunctions in hypothalamic-pituitary-adrenal (HPA) axis have been reported for several mental disorders. While major depressive disorder (MDD) as well as borderline personality disorder (BPD) seem to be characterized by enhanced cortisol release in concert with a reduced feedback sensitivity of the HPA axis, in posttraumatic stress disorder (PTSD) a contrary picture has been reported. Despite the fact that altered GR function has been discussed for these disorders only very few studies have investigated the effects of glucocorticoids on cognitive performance in these patients so far. In a series of studies, we investigated the effects of glucocorticoids on cognition (i.e. declarative memory, working memory and response inhibition) in different mental disorders such as MDD, PTSD and BPD. While in patients with MDD cortisol administration failed to effect memory retrieval, patients with PTSD and BPD showed enhanced rather than impaired memory retrieval after cortisol administration. These results indicate an altered sensitivity to cortisol in these disorders. Results from one of our recent studies in the field of social cognition underline the importance of the MR. We found that emotional empathy was enhanced through stimulation of the MR via fludrocortisone in healthy participants and women with BPD. This review aims to integrate these findings and discuss potential mechanisms and implications. Copyright © 2014 Elsevier Ltd. All rights reserved.

  17. Deep sleep after social stress : NREM sleep slow-wave activity is enhanced in both winners and losers of a conflict

    NARCIS (Netherlands)

    Kamphuis, Jeanine; Lancel, Marike; Koolhaas, Jaap M.; Meerlo, Peter

    Sleep is considered to be a recovery process of prior wakefulness. Not only duration of the waking period affects sleep architecture and sleep EEG, the quality of wakefulness is also highly important. Studies in rats have shown that social defeat stress, in which experimental animals are attacked

  18. 2000 Volvo Award winner in basic science studies: Exogenous tumor necrosis factor-alpha mimics nucleus pulposus-induced neuropathology. Molecular, histologic, and behavioral comparisons in rats.

    Science.gov (United States)

    Igarashi, T; Kikuchi, S; Shubayev, V; Myers, R R

    2000-12-01

    This study tested the hypothesis that the 17-kDa form of tumor necrosis factor-alpha is the pathophysiologic agent expressed by herniated nucleus pulposus in vivo that is primarily responsible for the histologic and behavioral manifestations of experimental sciatica associated with herniated lumbar discs. The authors determined the molecular weight and concentration of active tumor necrosis factor-alpha in rat herniated disc and used exogenous tumor necrosis factor-alpha at the same molecular weight to study its neuropathologic effect on rat nerve root and dorsal root ganglion preparations in vivo. Expressed by herniated nucleus pulposus in culture, tumor necrosis factor-alpha causes neuropathologic injury in nerve roots and neuropathic pain states in which mechanical allodynia is seen in response to peripheral stimuli. Western blotting was used to identify the molecular weight of the operative tumor necrosis factor-alpha protein form, and measures of optical density were used for semiquantitative determination of concentration. Plastic-embedded nerve roots and dorsal root ganglion were used for neuropathologic evaluation, and von Frey stimulation was used to quantify mechanical allodynia. The 17-kDa form of tumor necrosis factor-alpha is expressed by herniated nucleus pulposus at a concentration of approximately 0.48 ng per herniated rat lumbar disc. Exogenous tumor necrosis factor-alpha applied in vivo to rat nerve roots produced neuropathologic changes and behavior deficits that mimicked experimental studies with herniated nucleus pulposus applied to nerve roots. The data reinforce other evidence that tumor necrosis factor-alpha is involved in mechanisms of neuropathic pain.

  19. 2001 Volvo Award Winner in Basic Science Studies: Effect of nutrient supply on the viability of cells from the nucleus pulposus of the intervertebral disc.

    Science.gov (United States)

    Horner, H A; Urban, J P

    2001-12-01

    Disc cell viability was analyzed in relation to nutrient supply and cellular demand in vitro in a diffusion chamber. To determine relations among nutrient supply, nutrient concentrations. and cell viability. Although a fall in nutrient supply has long been thought the cause of disc degeneration in vivo, little information exists about the effects of nutrient levels or supply on cell viability and metabolism. Isolated bovine nucleus cells were cultured in agarose gels in a diffusion chamber up to 13 days. Nutrients were supplied to the open sides of the chamber and diffused through the gel to the center, 12.5 mm away from the nutrient supply, in a configuration analogous to that of the disc in vivo. Profiles of cell viability and concentration of glycosaminoglycans across the chamber were measured in relation to cell density and medium composition. Cells remained viable across the chamber at low cell densities. However, at higher densities, cells in the center of the chamber died. The viable distance from the nutrient supply fell with an increase in cell density. Glucose was a critical nutrient. Survival was also poor at acidic pH (6.0). At 0% oxygen, disc cells survived up to 13 days with no loss of viability, but produced very little proteoglycan. The results support the idea that maximum cell density in the disc is regulated by nutritional constraints, and that a fall in nutrient supply reduces the number of viable cells in the disc and thus leads to degeneration.

  20. 1997 Volvo Award winner in clinical studies. Degenerative lumbar spondylolisthesis with spinal stenosis: a prospective, randomized study comparing decompressive laminectomy and arthrodesis with and without spinal instrumentation.

    Science.gov (United States)

    Fischgrund, J S; Mackay, M; Herkowitz, H N; Brower, R; Montgomery, D M; Kurz, L T

    1997-12-15

    This prospective study analyzed the influence of transpedicular instrumented on the operative treatment of patients with degenerative spondylolisthesis and spinal stenosis. To determine whether the addition of transpedicular instrumented improves the clinical outcome and fusion rate of patients undergoing posterolateral fusion after decompression for spinal stenosis with concomitant degenerative spondylolisthesis. Decompression is often necessary in the treatment of symptomatic patients who have degenerative spondylolisthesis and spinal stenosis. Results of recent studies demonstrated that outcomes are significantly improved if posterolateral arthrodesis is performed at the listhesed level. A meta-analysis of the literature concluded that adjunctive spinal instrumentation for this procedure can enhance the fusion rate, although the effect on clinical outcome remains uncertain. Seventy-six patients who had symptomatic spinal stenosis associated with degenerative lumbar spondylolisthesis were prospectively studied. All patients underwent posterior decompression with concomitant posterolateral intertransverse process arthrodesis. The patients were randomized to a segmental transpedicular instrumented or noninstrumented group. Sixty-seven patients were available for a 2-year follow-up. Clinical outcome was excellent or good in 76% of the patients in whom instrumentation was placed and in 85% of those in whom no instrumentation was placed (P = 0.45). Successful arthrodesis occurred in 82% of the instrumented cases versus 45% of the noninstrumented cases (P = 0.0015). Overall, successful fusion did not influence patient outcome (P = 0.435). In patients undergoing single-level posterolateral fusion for degenerative spondylolisthesis with spinal stenosis, the use of pedicle screws may lead to a higher fusion rate, but clinical outcome shows no improvement in pain in the back and lower limbs.

  1. The 2003 ISMS Practice Prize Winner: Optimizing Rhenania's Direct Marketing Business Through Dynamic Multilevel Modeling (DMLM) in a Multicatalog-Brand Environment

    OpenAIRE

    Ralf Elsner; Manfred Krafft; Arnd Huchzermeier

    2004-01-01

    We introduce Dynamic Multilevel Modeling (DMLM) to a multicatalog-brand environment to determine the optimal frequency, size, and customer segmentation of direct marketing activities. This optimization method leverages multicatalog-brand effects including the utilization of prior customer ordering behavior, maximization of customer value and customer share, and economies of scale and scope in printing and mailing. This enhancement of the original DMLM-approach is called Dynamic Multidimension...

  2. Which Dengue Vaccine Approach Is the Most Promising, and Should We Be Concerned about Enhanced Disease after Vaccination? There Is Only One True Winner.

    Science.gov (United States)

    Halstead, Scott B

    2017-07-17

    The scientific community now possesses information obtained directly from human beings that makes it possible to understand why breakthrough-enhanced dengue virus (DENV) infections occurred in children receiving Sanofi Pasteur's Dengvaxia tetravalent live attenuated vaccine and to predict the possibility of breakthrough-enhanced DENV infections following immunization with two other tetravalent live attenuated vaccines now in phase III testing. Based upon recent research, Dengvaxia, lacking DENV nonstructural protein antigens, did not protect seronegatives because it failed to raise a competent T-cell response and/or antibodies to NS1. It is also possible that chimeric structure does not present the correct virion conformation permitting the development of protective neutralizing antibodies. A premonitory signal shared by the Sanofi Pasteur and the Takeda vaccines was the failure of fully immunized subhuman primates to prevent low-level viremia and/or anamnestic antibody responses to live DENV challenge. The vaccine developed by the National Institute of Allergy and Infectious Diseases (National Institutes of Health [NIH]) has met virtually all of the goals needed to demonstrate preclinical efficacy and safety for humans. Each monovalent vaccine was comprehensively studied for reactogenicity and immunogenicity in human volunteers. Protective immunity in subjects receiving tetravalent candidate vaccines was evidenced by the fact that when vaccinated subjects were given further doses of vaccine or different strains of DENV the result was "solid immunity," a nonviremic and nonanamnestic immune response. Copyright © 2017 Cold Spring Harbor Laboratory Press; all rights reserved.

  3. Using Young Adult Literature to Provide Case Studies for Discussion of Bullying: An Analysis of the 2014 Pura Belpré Award Winner

    Science.gov (United States)

    Cummins, Amy

    2014-01-01

    Analyzing Meg Medina's young adult novel "Yaqui Delgado Wants to Kick Your Ass" (2013) through the lens of multidisciplinary research on school bullying provides a case study in using young adult literature (YAL) to stimulate high school discussions about bullying. Strategies for using anti-bullying YAL and recommendations of additional…

  4. Winner of Young Writer's Competition: How loud is the unquiet mind? William Sargant (1907-88) and British psychiatry in the mid-20th century.

    Science.gov (United States)

    Li Shen Ooi, Joanne

    2012-05-01

    William Walters Sargant (1907-1988) is credited, for better or for worse, with putting physicalist psychiatry on the map--at the expense of the dictum 'primum non nocere' (first do no harm). He was an outspoken supporter and practitioner of what he termed the 'practical rather than philosophical approaches' to the treatment of mental illness. This paper examines Sargant's fascinating career, beginning with the reasons behind lifelong passion for radical psychiatry, then discusses the various physical treatments he pioneered and publicized during his three decades at St Thomas' including prolonged electroconvulsive therapy, insulin coma therapy, dangerous combinations of antidepressants and, most notably, prefrontal leucotomy. His heady mix of dogma and charisma enabled him to get away with flying in the face of evidence-based medicine--but not without courting the considerable controversy and contempt that was to so blacken his reputation posthumously. This paper ends with comments on misguided and misplaced enthusiasm in the history of therapeutics, acknowledgement of Sargant's positive contributions to psychiatry and finally a reminder not to be tempted to pass post hoc judgement on the man or his legacy all too quickly.

  5. Professor Paul Crutzen, the winner of the Nobel prize: The discovery of the ozone hole - knowledge and vision; Nobelpreistraeger Prof. Paul Crutzen: Entdeckung des Ozonlochs - Wissen und Vision

    Energy Technology Data Exchange (ETDEWEB)

    Crutzen, P.; Dellert-Ritter, M.

    1997-02-01

    On 10 December 1995, Professor Crutzen was awarded the Nobel prize for his epoch-making achievements in the field of atmospheric chemistry. This award underlines also Professor Crutzen`s commitment to the protection of the atmosphere. The atmospheric researcher discovered how sensitively the ozone layer reacts to air pollution. His work, together with that of others, led to the ban on ozone-depleting chlorofluorocarbons. As early as in 1970, Professor Crutzen demonstrated that nitrogen oxides react catalytically with ozone. His think tank provided numerous stimuli for further, intense research on atmospheric chemistry, which triggered a debate on the protection of the thinning ozone layer also among politicians. (orig.) [Deutsch] Am 10. Dezember 1995 wurde Prof. Crutzen fuer seine bahnbrechenden Leistungen auf dem Gebiet der Atmosphaerenchemie mit dem Nobelpreis geehrt. Diese Anerkennung unterstreicht auch das Engagement von Prof. Crutzen zum Schutz der Ozonschicht. Der Atmosphaerenforscher Prof. Crutzen entdeckte, wie empfindlich die Ozonschicht auf Luftverunreinigungen reagiert. Seine Arbeiten fuehrten mit zum Verbot der ozonvernichtenden Fluorchlorkohlenwasserstoffe. Bereits 1970 wies Prof. Crutzen nach, dass Stickstoffoxide katalytisch mit Ozon reagieren. Aus der Ideenfabrik von Prof. Crutzen kamen zahlreiche Anregungen fuer weitere intensive Forschungen zur Chemie der Atmosphaere, die auch unter Politikern eine Debatte ueber den Schutz der hauchduennen Ozonschicht ausloeste. (orig.)

  6. ISSLS Prize winner: Increased innervation and sensory nervous system plasticity in a mouse model of low back pain due to intervertebral disc degeneration.

    Science.gov (United States)

    Miyagi, Masayuki; Millecamps, Magali; Danco, Alexander T; Ohtori, Seiji; Takahashi, Kazuhisa; Stone, Laura S

    2014-08-01

    Immunohistochemical and behavioral study using the SPARC (secreted protein, acidic, rich in cysteine)-null mouse model of low back pain (LBP) associated with accelerated intervertebral disc (IVD) degeneration. To determine if behavioral signs of LBP in SPARC-null mice are accompanied by sensory nervous system plasticity. IVD pathology is a significant contributor to chronic LBP. In humans and rodents, decreased expression of SPARC is associated with IVD degeneration. We previously reported that SPARC-null mice exhibit age-dependent behavioral signs of chronic axial LBP and radiating leg pain. SPARC-null and age-matched control young, middle-aged, and old mice (1.5, 6, and 24 mo of age, respectively) were evaluated. Cutaneous hind paw sensitivity to cold, heat, and mechanical stimuli were evaluated as measures of radiating pain. The grip force and tail suspension assays were performed to evaluate axial LBP. Motor impairment was assessed using an accelerating rotarod. IVD innervation was identified by immunohistochemistry targeting the nerve fiber marker PGP9.5 and the sensory neuropeptide calcitonin gene-related peptide (CGRP). Sensory nervous system plasticity was evaluated by quantification of CGRP- and neuropeptide-Y-immunoreactivity (-ir) in dorsal root ganglia neurons and CGRP-ir, GFAP-ir (astrocyte marker), and Iba-1-ir (microglia marker) in the spinal cord. SPARC-null mice developed hypersensitivity to cold, axial discomfort, age-dependent motor impairment, age-dependent increases in sensory innervation in and around the IVDs, age-dependent upregulation of CGRP and neuropeptide-Y in dorsal root ganglia, and age-dependent upregulation of CGRP, microglia, and astrocytes in the spinal cord dorsal horn. Increased innervation of degenerating IVDs by sensory nerve fibers and the neuroplasticity in sensory neurons and spinal cord could contribute to the underlying pathobiology of chronic discogenic LBP. N/A.

  7. Duncan Tanner Essay Prize Winner 2014. Against the 'Sacred Cow': NHS Opposition and the Fellowship for Freedom in Medicine, 1948-72.

    Science.gov (United States)

    Seaton, Andrew

    2015-01-01

    This essay recovers organized opposition to the National Health Service (NHS) by considering the Fellowship for Freedom in Medicine (FFM), a conservative organization of doctors who challenged the 'Sacred Cow' of nationalized healthcare in the 1950s and 1960s. While there has been little interest in anti-NHS politics because of shortcomings in the institution's historiography, this study suggests ways a new history of the service can be written. Central to that project is taking the broader ideological and emotive quality of the NHS seriously, and appreciating the way, for all sides of the political spectrum, as well as the general public, the service has always been a contested symbol of post-war British identity. This essay argues that two NHS 'crises'--panics over costs, and disillusionment within general practice--were not merely disagreements over budgets and pay-packets but politically charged moments infused with conservative anxieties over Britain's post-war trajectory. The FFM imagined the NHS as an economically dangerous bureaucratic machine that crushed medical independence and risked pushing the country towards dictatorship. Allies within the Conservative Party, private health insurance industry, and free-market 'think-tanks' worked with the FFM to challenge defences of both the service's operation and meaning. To appreciate why the NHS remains 'the closest thing the English have to a religion', one must consider the apostates as well as the faithful.

  8. The Princess and the Poor Self-Image: An Analysis of Newbery Medal Winners for Gender Bias and Female Underrepresentation Leading into the Twenty-First Century

    Directory of Open Access Journals (Sweden)

    Melissa A. McCleary

    2014-05-01

    Full Text Available This study analyzes how 12 recent (2000-2011 Newbery Medal-winning books represent gender. The study counts how many of the books’ characters represent progressive or traditional gender roles, how many male and female characters represent each character category (protagonist, antagonist, major, and minor, how many strong female characters are accepted or rejected by their peers, how many characters hold stereotypical gender beliefs about themselves or their peers, and how many works contain balanced feminist perspectives. The study finds equitable female representation, but the study also finds a bias toward traditional male stereotypes. The results indicate a general acceptance of strong female characters and a balanced representation of females, regardless of a historical fiction classification. These results suggest that characters in Newbery Medal-winning books represent gender more equally and less stereotypically compared to characters in works of earlier decades.

  9. Share and share alike or winner take all?: the influence of social value orientation upon coice and recall of negotiation heuristics

    NARCIS (Netherlands)

    de Dreu, C.K.W.; Boles, T.

    1998-01-01

    Two experiments test the hypothesis that social value orientation influences choice and recall of heuristics in individuals preparing for negotiation. Consistent with predictions, Study 1 shows that in the preparation phase, negotiators with a prosocial value orientation choose more cooperative

  10. MO-DE-207B-01: JACK FOWLER JUNIOR INVESTIGATOR COMPETITION WINNER: Between Somatic Mutations and PET-Based Radiomic Features in Non-Small Cell Lung Cancer

    Energy Technology Data Exchange (ETDEWEB)

    Yip, S; Coroller, T; Rios Velazquez, E; Parmar, C; Mak, R; Aerts, H [Brigham and Women’s Hospital, Dana Farber Cancer Institute, and Harvard Medical School, Boston, MA (United States); Kim, J [Brigham and Women’s Hospital, Boston Children’s Hospital and Harvard Medical School, Boston, MA (United States)

    2016-06-15

    Purpose: Although PET-based radiomic features have been proposed to quantify tumor heterogeneity and shown promise in outcome prediction, little is known about their relationship with tumor genetics. This study assessed the association of [{sup 18}F]fluorodeoxyglucose (FDG)-PET-based radiomic features with non-small cell lung cancer (NSCLC) mutations. Methods: 348 NSCLC patients underwent FDG-PET/CT scans before treatment and were tested for genetic mutations. 13% (44/348) and 28% (96/348) patients were found to harbor EGFR (EGFR+) and KRAS (KRAS+) mutations, respectively. We evaluated nineteen PET-based radiomic features quantifying phenotypic traits, and compared them with conventional PET features (metabolic tumor volume (MTV) and maximum-SUV). The association between the feature values and mutation status was evaluated using the Wilcoxcon-rank-sum-test. The ability of each measure to predict mutations was assessed by the area under the receiver operating curve (AUC). Noether’s test was used to determine if the AUCs were significantly from random (AUC=0.50). All p-values were corrected for multiple testing by controlling the false discovery rate (FDR{sub Wilcoxon} and FDR{sub Noether}) of 10%. Results: Eight radiomic features, MTV, and maximum-SUV, were significantly associated with the EGFR mutation (FDR{sub Wilcoxon}=0.01–0.10). However, KRAS+ demonstrated no significantly distinctive imaging features compared to KRAS− (FDR{sub Wilcoxon}≥0.92). EGFR+ and EGFR− were significantly discriminated by conventional PET features (AUC=0.61, FDR{sub Noether}=0.04 for MTV and AUC=0.64, FDR{sub Noether}=0.01 for maximum-SUV). Eight radiomic features were significantly predictive for EGFR+ compared to EGFR− (AUC=0.59–0.67, FDR{sub Noether}=0.0032–0.09). Normalized-inverse-difference-moment outperformed all features in predicting EGFR mutation (AUC=0.67, FDR{sub Noether}=0.0032). Moreover, only the radiomic feature normalized-inverse-difference-moment could significantly predict KRAS+ from EGFR+ (AUC=0.65, FDR{sub Noether}=0.05). All measures failed to predict KRAS+ from KRAS− (AUC=0.50–0.54, FDR{sub Noether}≥0.92). Conclusion: PET imaging features were strongly associated with EGFR mutations in NSCLC. Radiomic features have great potential in predicting EGFR mutations. Our study may help develop a non-invasive imaging biomarker for EGFR mutation. R.M. has consulting interests with Amgen.

  11. A prospective randomized controlled trial of the natural history of idiopathic scoliosis versus treatment with the SpineCor brace. Sosort Award 2011 winner.

    Science.gov (United States)

    Coillard, C; Circo, A B; Rivard, C H

    2014-10-01

    The purpose of this randomized controlled trial was to evaluate the efficacy of the Dynamic SpineCor brace for early idiopathic scoliosis (15°-30°) compared to the natural evolution of the disease. 68 patients participated in this study (32 treated and 36 controls) with at least 5 years follow-up. The inclusion criteria were: 1) high risk of evolution: family history and/or proven progressive; 2) no significant pathological malformation of the spine; 3) initial Cobb angle between 15° and 30°; 4) risser 0, 1 or 2. Assessment of brace efficacy included the percentage of patients who have 5º or less curve progression and the percentage of patients who have 6º or more progression at skeletal maturity. At five-year follow-up a correction was achieved in 50% of treated patient and only in 9.5% of controls, stabilization in 42.3% treated and 47.7% in controls and progression in 26.9% for the treated group and 42.8% for controls. For the control patients we considered as a failure if the Cobb angle worsened by more then 5° from the original angle and the patient then received treatment. The results 5 years after the treatment suggested that the SpineCor brace reduced the probability of the progression of early idiopathic scoliosis comparing with its natural history. Moreover, the positive outcome appears to be maintained in the long term.

  12. Energy Performance and Thermal Comfort of a High Efficiency House: RhOME for denCity, Winner of Solar Decathlon Europe 2014

    Directory of Open Access Journals (Sweden)

    Gabriele Battista

    2015-07-01

    Full Text Available The increase of people living in large cities and the expansion of new urban areas are keys to defining new sustainable models. It is estimated that about 70% of the EU population lives in urban areas, and it is expected to reach 80% by 2030. Consequently, it is important to find a new concept of buildings that can reduce the total energy consumption. The Solar Decathlon is an international university competition, born in 2002, created by the U.S. State Energy Department (DOE. Students are challenged to design and operate a full-scale, innovative and sustainable house able to exploit solar radiation as its sole energy source. The objective of the competition is to promote research and education in sustainable architecture and solar energy fields. This paper presents an overview on the contribution of LIFT (Interdisciplinary Laboratory of Technical Physics of Roma Tre University to the winning project of the Solar Decathlon Europe 2014 competition: The RhOME for denCity. This project consists of a building properly designed to produce a solar-powered house that is cost-effective, energy-efficient, and attractive.

  13. Gerir a dissidência: vencedores e vencidos na espanha franquista Managing dissent: winners and losers in Franco’s Spain

    Directory of Open Access Journals (Sweden)

    Fernando Ampudia de Haro

    2010-01-01

    Full Text Available O objectivo do artigo é oferecer uma perspectiva geral acerca da dicotomia “vencedor/vencido” como resultado do novo equilíbrio de poder que emerge em Espanha após a guerra civil. A administração deste equilíbrio por parte do regime franquista inclui a gestão do contingente dos vencidos. Argumenta-se que a distinção “vencedor/vencido” proporciona o fundamento sociológico necessário que converte a metáfora meta-histórica das “duas Espanhas” numa realidade social durante o franquismo.The aim of this paper is to offer a general perspective on the “victor/vanquished” dichotomy as a result of the new power balance in the period following the Spanish Civil war. The power balance administered by the Franco regime includes, inevitably, the “vanquished” management. I argue that the “victor/vanquished” distinction provides a sociological background to speak about the “two Spains” meta-historical metaphor as a social reality during Francoism.

  14. British Orthodontic Society, Chapman Prize Winner 2003. A novel in vitro culture model to investigate the reaction of the dentine-pulp complex to orthodontic force.

    Science.gov (United States)

    Dhopatkar, A A; Sloan, A J; Rock, W P; Cooper, P R; Smith, A J

    2005-06-01

    To develop a novel mandible slice organ culture model to investigate the effects of externally applied force on the dentine-pulp complex. In vitro organ culture. School of Dentistry, Birmingham, UK. Transverse 2 mm thick sections were cut from the mandibles of five 28-day-old male Wistar rats. Serial sections were used for control and test pairs. Springs made from 0.016-inch and 0.019 x 0.025-inch stainless steel wires were used to apply a 50 g tensile or compressive force, respectively, to test specimens. Control and test specimens were cultured for 5 days in a humidified incubator with 5% CO(2) at 37 degrees C and processed for routine histological investigation. Nine more rats were used to provide control and compression test pairs where the pulps were extirpated after 3 days culture and total RNA isolated for gene expression analysis by reverse transcriptase polymerase chain reaction (RT-PCR). Histology showed the dental and supporting tissues maintained a healthy appearance in the control cultures after culture. Histomorphometric analysis revealed a 20-27% increase in pulp fibroblast density in test specimens compared with controls. Gene expression analyses revealed up-regulation in the test groups of PCNA, c-Myc, Collagen 1alpha, TGF-beta1 and alkaline phosphatase, whilst expression of osteocalcin was reduced. The results demonstrated that the present organ culture technique provides a valuable in vitro experimental model for studying the effects of externally applied forces. These forces stimulated a cellular response in the pulp chamber characterized by altered gene expression and proliferation of fibroblasts; the latter being unaffected by the nature of the force in terms of compression or tension.

  15. Society News: Fellow sets new world record; RAS thesis prize winners; Galileo in the courtyard; Need a room? Society announces new award for early-career researchers

    Science.gov (United States)

    2009-10-01

    Generous sponsorship from Winton Capital Management has made possible two new RAS Awards, to be given annually to postdoctoral researchers who have made outstanding progress in the years immediately after their PhD.

  16. Stress-induced redistribution of immune cells--from barracks to boulevards to battlefields: a tale of three hormones--Curt Richter Award winner.

    Science.gov (United States)

    Dhabhar, Firdaus S; Malarkey, William B; Neri, Eric; McEwen, Bruce S

    2012-09-01

    The surveillance and effector functions of the immune system are critically dependent on the appropriate distribution of immune cells in the body. An acute or short-term stress response induces a rapid and significant redistribution of immune cells among different body compartments. Stress-induced leukocyte redistribution may be a fundamental survival response that directs leukocyte subpopulations to specific target organs during stress, and significantly enhances the speed, efficacy and regulation of an immune response. Immune responses are generally enhanced in compartments (e.g., skin) that are enriched with leukocytes, and suppressed in compartments that are depleted of leukocytes during/following stress. The experiments described here were designed to elucidate the: (1) Time-course, trajectory, and subpopulation-specificity of stress-induced mobilization and trafficking of blood leukocytes. (2) Individual and combined actions of the principal stress hormones, norepinephrine (NE), epinephrine (EPI), and corticosterone (CORT), in mediating mobilization or trafficking of specific leukocyte subpopulations. (3) Effects of stress/stress hormones on adhesion molecule, L-selectin (CD62L), expression by each subpopulation to assess its adhesion/functional/maturation status. Male Sprague Dawley rats were stressed (short-term restraint, 2-120 min), or adrenalectomized and injected with vehicle (VEH), NE, EPI, CORT, or their combinations, and blood was collected for measurement of hormones and flow cytometric quantification of leukocyte subpopulations. Acute stress induced an early increase/mobilization of neutrophils, lymphocytes, helper T cells (Th), cytolytic T cells (CTL), and B cells into the blood, followed by a decrease/trafficking of all cell types out of the blood, except neutrophil numbers that continued to increase. CD62L expression was increased on neutrophils, decreased on Th, CTL, and natural killer (NK) cells, and showed a biphasic decrease on monocytes & B cells, suggesting that CD62L is involved in mediating the redistribution effects of stress. Additionally, we observed significant differences in the direction, magnitude, and subpopulation specificity of the effects of each hormone: NE increased leukocyte numbers, most notably CD62L⁻/⁺ neutrophils and CD62L⁻ B cells. EPI increased monocyte and neutrophil numbers, most notably CD62L⁻/⁺ neutrophils and CD62L⁻ monocytes, but decreased lymphocyte numbers with CD62L⁻/⁺ CTL and CD62L⁺ B cells being especially sensitive. CORT decreased monocyte, lymphocyte, Th, CTL, and B cell numbers with CD62L⁻ and CD62L⁺ cells being equally affected. Thus, naïve (CD62L⁺) vs. memory (CD62L⁻) T cells, classical (CD62L⁺) vs. non-classical (CD62L⁻) monocytes, and similarly distinct functional subsets of other leukocyte populations are differentially mobilized into the blood and trafficked to tissues by stress hormones. Stress hormones orchestrate a large-scale redistribution of immune cells in the body. NE and EPI mobilize immune cells into the bloodstream, and EPI and CORT induce traffic out of the blood possibly to tissue surveillance pathways, lymphoid tissues, and sites of ongoing or de novo immune activation. Immune cell subpopulations appear to show differential sensitivities and redistribution responses to each hormone depending on the type of leukocyte (neutrophil, monocyte or lymphocyte) and its maturation/functional characteristics (e.g., non-classical/resident or classical/inflammatory monocyte, naïve or central/effector memory T cell). Thus, stress hormones could be administered simultaneously or sequentially to induce specific leukocyte subpopulations to be mobilized into the blood, or to traffic from blood to tissues. Stress- or stress hormone-mediated changes in immune cell distribution could be clinically harnessed to: (1) Direct leukocytes to sites of vaccination, wound healing, infection, or cancer and thereby enhance protective immunity. (2) Reduce leukocyte traffic to sites of inflammatory/autoimmune reactions. (3) Sequester immune cells in relatively protected compartments to minimize exposure to cytotoxic treatments like radiation or localized chemotherapy. (4) Measure biological resistance/sensitivity to stress hormones in vivo. In keeping with the guidelines for Richter Award manuscripts, in addition to original data we also present a model and synthesis of findings in the context of the literature on the effects of short-term stress on immune cell distribution and function. Copyright © 2012 Elsevier Ltd. All rights reserved.

  17. WE-DE-BRA-01: SCIENCE COUNCIL JUNIOR INVESTIGATOR COMPETITION WINNER: Acceleration of a Limited-Angle Intrafraction Verification (LIVE) System Using Adaptive Prior Knowledge Based Image Estimation

    Energy Technology Data Exchange (ETDEWEB)

    Zhang, Y; Yin, F; Ren, L [Duke University Medical Center, Durham, NC (United States); Zhang, Y [UT Southwestern Medical Ctr at Dallas, Dallas, TX (United States)

    2016-06-15

    Purpose: To develop an adaptive prior knowledge based image estimation method to reduce the scan angle needed in the LIVE system to reconstruct 4D-CBCT for intrafraction verification. Methods: The LIVE system has been previously proposed to reconstructs 4D volumetric images on-the-fly during arc treatment for intrafraction target verification and dose calculation. This system uses limited-angle beam’s eye view (BEV) MV cine images acquired from the treatment beam together with the orthogonally acquired limited-angle kV projections to reconstruct 4D-CBCT images for target verification during treatment. In this study, we developed an adaptive constrained free-form deformation reconstruction technique in LIVE to further reduce the scanning angle needed to reconstruct the CBCT images. This technique uses free form deformation with energy minimization to deform prior images to estimate 4D-CBCT based on projections acquired in limited angle (orthogonal 6°) during the treatment. Note that the prior images are adaptively updated using the latest CBCT images reconstructed by LIVE during treatment to utilize the continuity of patient motion.The 4D digital extended-cardiac-torso (XCAT) phantom was used to evaluate the efficacy of this technique with LIVE system. A lung patient was simulated with different scenario, including baseline drifts, amplitude change and phase shift. Limited-angle orthogonal kV and beam’s eye view (BEV) MV projections were generated for each scenario. The CBCT reconstructed by these projections were compared with the ground-truth generated in XCAT.Volume-percentage-difference (VPD) and center-of-mass-shift (COMS) were calculated between the reconstructed and the ground-truth tumors to evaluate the reconstruction accuracy. Results: Using orthogonal-view of 6° kV and BEV- MV projections, the VPD/COMS values were 12.7±4.0%/0.7±0.5 mm, 13.0±5.1%/0.8±0.5 mm, and 11.4±5.4%/0.5±0.3 mm for the three scenarios, respectively. Conclusion: The technique enables LIVE to accurately reconstruct 4D-CBCT images using only orthogonal 6° angle, which greatly improves the efficiency and reduces dose of LIVE for intrafraction verification.

  18. The life of Georges Charpak : a mini-exhibition all about the winner of the 1992 Nobel Prize for Physics in the Globe

    CERN Multimedia

    Maximilien Brice

    2005-01-01

    This renowned scientist revolutionised the detection of elementary particles, but is equally interested in other fields, such as medicine and primary science education. Follow the course of his life, a truly scientific and human story, through original manuscripts, archive film, and actual scientific instruments.

  19. Cult of the Sexless Casement with Special Reference to the Novel The Dream of the Celt by Mario Vargas Llosa (Nobel Prize Winner for Literature 2010

    Directory of Open Access Journals (Sweden)

    Jeffrey Dudgeon

    2014-01-01

    Full Text Available The Irish revolutionary Roger Casement, executed in 1916, has spawned an army of books, articles, and news stories, more about his diaries and the authenticity controversy that still surrounds them than about his seminal work encouraging and arming Irish separatism or his humanitarian investigations in the Congo and the Peruvian Amazon. His aura and image in life, and more so in death, was Christ-like. A cult developed that required him to be sexless. The more he was said to be an active homosexual, as graphically revealed in his journals, ironically, the more he was revered as an icon by his Catholic nationalist supporters. The entry of Nobel prizewinning novelist Mario Vargas Llosa to the field and his adoption of a mixed, even contradictory, view of Casement’s sexuality in his Dream of the Celt (2010 has sparked a new round of disputation particularly from Angus Mitchell, the foremost proponent of the diary forgery theory. This emerges in his extensive Field Day Review articles, one of which provides a full history of the controversy. 

  20. WE-DE-BRA-01: SCIENCE COUNCIL JUNIOR INVESTIGATOR COMPETITION WINNER: Acceleration of a Limited-Angle Intrafraction Verification (LIVE) System Using Adaptive Prior Knowledge Based Image Estimation

    International Nuclear Information System (INIS)

    Zhang, Y; Yin, F; Ren, L; Zhang, Y

    2016-01-01

    Purpose: To develop an adaptive prior knowledge based image estimation method to reduce the scan angle needed in the LIVE system to reconstruct 4D-CBCT for intrafraction verification. Methods: The LIVE system has been previously proposed to reconstructs 4D volumetric images on-the-fly during arc treatment for intrafraction target verification and dose calculation. This system uses limited-angle beam’s eye view (BEV) MV cine images acquired from the treatment beam together with the orthogonally acquired limited-angle kV projections to reconstruct 4D-CBCT images for target verification during treatment. In this study, we developed an adaptive constrained free-form deformation reconstruction technique in LIVE to further reduce the scanning angle needed to reconstruct the CBCT images. This technique uses free form deformation with energy minimization to deform prior images to estimate 4D-CBCT based on projections acquired in limited angle (orthogonal 6°) during the treatment. Note that the prior images are adaptively updated using the latest CBCT images reconstructed by LIVE during treatment to utilize the continuity of patient motion.The 4D digital extended-cardiac-torso (XCAT) phantom was used to evaluate the efficacy of this technique with LIVE system. A lung patient was simulated with different scenario, including baseline drifts, amplitude change and phase shift. Limited-angle orthogonal kV and beam’s eye view (BEV) MV projections were generated for each scenario. The CBCT reconstructed by these projections were compared with the ground-truth generated in XCAT.Volume-percentage-difference (VPD) and center-of-mass-shift (COMS) were calculated between the reconstructed and the ground-truth tumors to evaluate the reconstruction accuracy. Results: Using orthogonal-view of 6° kV and BEV- MV projections, the VPD/COMS values were 12.7±4.0%/0.7±0.5 mm, 13.0±5.1%/0.8±0.5 mm, and 11.4±5.4%/0.5±0.3 mm for the three scenarios, respectively. Conclusion: The technique enables LIVE to accurately reconstruct 4D-CBCT images using only orthogonal 6° angle, which greatly improves the efficiency and reduces dose of LIVE for intrafraction verification.

  1. Assessing Values in Historical Fiction Written for Children: A Content Analysis of the Winners of the Scott O'Dell Historical Fiction Award.

    Science.gov (United States)

    Edgington, William D.; Brabham, Edna Greene; Frost, Jami Bice

    1999-01-01

    Considers how teachers engage children in character education and analyzes core values in books winning the Scott O'Dell Historical Fiction Award. Finds that these books are rich sources for examples of core values that are common features of character-education programs. Observes many teachers using short stories and picture books to insert…

  2. Spacelabs Innovative Project Award winner--2008. Megacode simulation workshop and education video--a megatonne of care and Code blue: live and interactive.

    Science.gov (United States)

    Loucks, Lynda; Leskowski, Jessica; Fallis, Wendy

    2010-01-01

    Skill acquisition and knowledge translation of best practices can be successfully facilitated using simulation methods. The 2008 Spacelabs Innovative Project Award was awarded for a unique training workshop that used simulation in the area of cardiac life support and resuscitation to train multiple health care personnel in basic and advanced skills. The megacode simulation workshop and education video was an educational event held in 2007 in Winnipeg, MB, for close to 60 participants and trainers from multiple disciplines across the provinces of Manitoba and Northwestern Ontario. The event included lectures, live simulation of a megacode, and hands-on training in the latest techniques in resuscitation. The goals of this project were to promote efficiency and better outcomes related to resuscitation measures, to foster teamwork, to emphasize the importance of each team member's role, and to improve knowledge and skills in resuscitation. The workshop was filmed to produce a training DVD that could be used for future knowledge enhancement and introductory training of health care personnel. Substantial positive feedback was received and evaluations indicated that participants reported improvement and expansion of their knowledge of advanced cardiac life support. Given their regular participation in cardiac arrest codes and the importance of staying up-to-date on best practice, the workshop was particularly useful to health care staff and nurses working in critical care areas. In addition, those who participate less frequently in cardiac resuscitation will benefit from the educational video for ongoing competency. Through accelerating knowledge translation from the literature to the bedside, it is hoped that this event contributed to improved patient care and outcomes with respect to advanced cardiac life support.

  3. Long-term Shifts in Coral Communities On Shallow to Deep Reef Slopes of Curaçao and Bonaire: Are There Any Winners?

    NARCIS (Netherlands)

    de Bakker, D.M.; Meesters, E.H.; Bak, R.P.M.; Nieuwland, G.; van Duyl, F.C.

    2016-01-01

    Tropical coral reefs are among the most biologically diverse and economically important ecosystems on earth. Nevertheless, we found dramatic changes in coral communities on the reef slopes of Curaçao and Bonaire since 1973. Cover and abundance declined for virtually all coral species. The data show

  4. Physicians for the prevention of nuclear war. A portrayal of the Nobel prize winner. Betrifft: Aerzte gegen den Atomkrieg. Ein Portraet des Friedensnobelpreistraegers

    Energy Technology Data Exchange (ETDEWEB)

    Jogschies, R.

    1986-01-01

    The publication abstracted reports on the history and aims of IPPNW (International Physicians for the Prevention of Nuclear War). In recognition of their continuous and consistent international campaign of enlightenment its 140,000 members were awarded the peace Nobel prize in 1985. Emphasis is placed on the achievements and work of the Western Germany section of ''Physicians for the Prevention of Nuclear War''. The portrait is the first of its kind to comprehensibly acquaint even non-experts with the background, history and difficulties of the medical resistance to the dangers of nuclear war. Neither stopping at national or at political borders the medical hippocratic mission of fighting against a nuclear holocaust has brought about and developed a professional disinterestedness which is not equalled by any other kind of social and moral devotion. The publication analyses the worldwide threatening situation, the forgotten lesson taught by the past and the chances of medical protest. The result pointed out expresses an optimistic view. Chances are good if IPPNW does not only supply us with facts but also sets an example of modern morality. Interesting rudimentary attempts of initation can already be observed with other professions, for example among journalists.

  5. Op ’n mespunt. Die ontvangs van Johannes Calvyn in die denke van Willie Jonker

    Directory of Open Access Journals (Sweden)

    P. Naudé

    2012-02-01

    Full Text Available This paper, originally read as the fourth Willie Jonker commemoration lecture (October 2009, explores how the central tenets of Jonker’s theology have been fundamentally shaped by John Calvin. It is argued that Jonker’s very understanding of Reformed theology is derived from Calvin. Furthermore, on three issues, Calvin plays an important role: Jonker’s insistence on the visible unity of the church, the importance of social ethics, and the church as the people of God superseding the ethnic notion of a volkskerk. The paper concludes with a list of contemporary theological and ethical issues that may be addressed from the Calvin-Jonker line of thinking.

  6. Kuula. Kuu artist Sam Sparro. Kuu plaat / Mart Juur

    Index Scriptorium Estoniae

    Juur, Mart, 1964-

    2008-01-01

    Artistist Sam Sparrost. Heliplaatidest: "Sex And The City" Original Motion Picture Soundtrack, "Maestro: Blue Note Trip", Melvin/Soo/Remmel/Julm "Geografix", Alanis Morrisette "Flavors Of Entanglement", Guillemots "Red"

  7. Sitikas suudles kuud ja muusikat : haikud jazziga / Inna Grünfeldt

    Index Scriptorium Estoniae

    Grünfeldt, Inna, 1961-

    2008-01-01

    Rakvere rahvamaja keldrisaalis toimunud haiku- ja jazziõhtust, kus esinesid kirjanik Andres Ehin, kitarrist Mart Soo ja löökpillimängija Brian Melvin. Ka intervjuu Tokios oma haikukogumiku "Sitikas suudleb kuud" üllitanud Andres Ehiniga

  8. Popmuusika / Valner Valme

    Index Scriptorium Estoniae

    Valme, Valner, 1970-

    2006-01-01

    Uutest heliplaatidest The Vines "Vision Valley", Layo & Bushwacka "Feels Closer", Secret Machines "Ten Silver Drops", Novikov-Unt-Melvin "Painting", Sugababes "Taller In More Ways", The Ipanemas "Samba Is Our Gift", Dynamite Vikings "Seach For Happiness"

  9. 77 FR 27850 - Qualification of Drivers; Exemption Applications; Vision

    Science.gov (United States)

    2012-05-11

    ..., States subject drivers to knowledge and skills tests designed to evaluate their qualifications to operate...), Melvin D. Clark (GA), Jackie K. Cooper (UT), William C. Dempsey, Jr. (MA), Ryan C. Dugan (NY), Donald J...

  10. The Role of Cortical Plasticity in Recovery of Function Following Allogeneic Hand Transplantation

    Science.gov (United States)

    2014-10-01

    NUMBER University of Missouri 205a Melvin H. Marx Building 1416 Carrie Francke Drive Columbia, MO 65211 9...details • Refine devices and techniques used in protocols and conduct pilot tests: o Revised and tested somatosensory stimulation apparatus for face

  11. KSC-04PD-2010

    Science.gov (United States)

    2004-01-01

    KENNEDY SPACE CENTER, FLA. At Gainesville Elementary School, a NASA Explorer School in Gainesville, Ga., astronaut Leland Melvin hands a patch to a student for answering a question. Melvin joined Jim Jennings, deputy associate administrator for Institutions and Asset Management at NASA Headquarters, on the visit to the school to share the new vision for space exploration with the next generation of explorers. Melvin talked about the importance of teamwork and what it takes for mission success. Also visiting was KSC Deputy Director Woodrow Whitlow Jr., who talked with students about our destiny as explorers, NASAs stepping stone approach to exploring Earth, the Moon, Mars and beyond, how space impacts our lives, and how people and machines rely on each other in space. Melvin talked about the importance of teamwork and what it takes for mission success.

  12. HiEnergy Technologies announces scientific advisory board

    CERN Multimedia

    2003-01-01

    HiEnergy has named the physicists on their independent scientific advisory board. They include Nobel laureate Dr. Melvin Schwartz and Dr. Giovanni Fazio, Senior Physicist at the Harvard Smithsonian Centre (1/2 page).

  13. Effects of Increased Commercial Navigation Traffic on Freshwater Mussels in the Upper Mississippi River: Ten-Year Evaluation

    National Research Council Canada - National Science Library

    Miller, Andrew

    2002-01-01

    ... traffic at five historically prominent mussel beds in the upper Mississippi River (UMR). The purpose was to assess effects of increased navigation traffic caused by the newly completed Melvin Price Locks and Dam at Alton, IL...

  14. Respek vir die liturgiese teks: J. Calvyn en J.S. Bach | Schulze | Acta ...

    African Journals Online (AJOL)

    Despite obvious differences in terms of historical and theological aspects between Calvin and Bach, both share a respect for the priority of the Biblical text in worship.The anomaly between Calvin's engagement in the versification of the Psalter and Bach's preference for the literal (rather than a versified) use of the Biblical ...

  15. Calvin’s Theology of Creation and Providence. God’s Care and Human Fragility

    NARCIS (Netherlands)

    van der Kooi, C.

    2016-01-01

    This article describes some of the basic elements of John Calvin's theology of creation and providence by situating them within a trinitarian framework. By using metaphors such as mirror, theatre and garment, Calvin pictured the earth as a generous gift of the Creator within which God shows his

  16. Julma USA sõdurit ootab elu vanglas / Evelyn Kaldoja

    Index Scriptorium Estoniae

    Kaldoja, Evelyn, 1980-

    2011-01-01

    USA sõjavägi hakkab mõistma kohut veebel Calvin Gibbsi üle, keda peetakse afgaani tsiviilisikuid tapnud ja ohvrite laipu rüvetanud jõugu eestvedajaks. Calvin Gibbs eitab kõiki talle esitatud süüdistusi

  17. 77 FR 53248 - Culturally Significant Objects Imported for Exhibition Determinations: “Swiss Treasures: From...

    Science.gov (United States)

    2012-08-31

    ... DEPARTMENT OF STATE [Public Notice 8004] Culturally Significant Objects Imported for Exhibition Determinations: ``Swiss Treasures: From Biblical Papyrus and Parchment to Erasmus, Zwingli, Calvin, and Barth... Parchment to Erasmus, Zwingli, Calvin, and Barth,'' imported from abroad for temporary exhibition within the...

  18. Johannes Calvyn as pedagoog | Schoeman | HTS Teologiese ...

    African Journals Online (AJOL)

    John Calvin as pedagogue Calvin was not only a theologian, but a competent pedagogue as well. He set a high value on education, and promoted it actively, but never systematically committed his views on it to paper. His educational views were not purely educational, but connected to a particular theological view.

  19. History of Higher Education Annual, 1985.

    Science.gov (United States)

    Karp, Alan; And Others

    1985-01-01

    This volume of the History of Higher Education Annual contains five articles. Alan Karp's essay, "John Calvin and the Geneva Academy: Roots of the Board of Trustees," discusses the reoganization and government of the Geneva Academy and Calvin's unsuccessful struggle to establish a church independent of lay control. Institutional…

  20. Die samehang tussen teologiese teorie en praxis: 'n Gevallestudie ...

    African Journals Online (AJOL)

    Analysis of the Institutes of the Christian Religion of John Calvin. Michigan: Baker Bark House. Calvyn, J 1863-1900. Opera quae supersunt omnia; Corpus Refonnatorum; Ed Baum. Cunitz et Reuss. Brunsvigiae: Schwetschke et filium. — 1961. Johannes Calvins Lebenswerk in seinen Briefen. TransI by R Schwarz.

  1. Die priesterskap van die gelowiges soos Calvyn dit gesien het

    Directory of Open Access Journals (Sweden)

    A. D. Pont

    1989-01-01

    Full Text Available The priesthood of all believers as seen by Calvin The Lutheran thesis of the priesthood of all believers was also taken over by John Calvin. The position of this thesis in Calvin’s theology is examined and it is shown that Calvin does not trea t this thesis as a separate statement. A short introduction is given of the main points Calvin explores when he discusses the meaning of the thesis. In the end it is shown that Calvin developed the thesis of the universal priesthood in such a low-key form to preserve the order in the Church and the prime position of the preaching of the gospel.

  2. Enkele opmerkings oor Johannes Calvyn se stellings oor die capita doctrina necessaria

    Directory of Open Access Journals (Sweden)

    A.D. Pont

    1995-09-01

    Full Text Available Some remarks on John Calvin's statements on the capita doctrina necessariaCalvin mentions that there are capita doctrina necessaria in the whole of the church's doctrine. The meaning of the summa religionis is explored in relation to Calvin's concept of the church. It is shown that Calvin sees the church as a pneumatic organism and not, in the first place, as an institute or an organisational unit. This becomes clear when his letter of dedication to the Lutheran pastors in 1556 is also taken in account. Calvin's summa religionis is seen as an argument that needs to be taken in account in contemporary discussions on the doctrinal centre of the church and on church unity.

  3. Low delay and area efficient soft error correction in arbitration logic

    Science.gov (United States)

    Sugawara, Yutaka

    2013-09-10

    There is provided an arbitration logic device for controlling an access to a shared resource. The arbitration logic device comprises at least one storage element, a winner selection logic device, and an error detection logic device. The storage element stores a plurality of requestors' information. The winner selection logic device selects a winner requestor among the requestors based on the requestors' information received from a plurality of requestors. The winner selection logic device selects the winner requestor without checking whether there is the soft error in the winner requestor's information.

  4. 2001 Volvo Award Winner in Clinical Studies: Effects of a media campaign on back pain beliefs and its potential influence on management of low back pain in general practice.

    Science.gov (United States)

    Buchbinder, R; Jolley, D; Wyatt, M

    2001-12-01

    Quasi-experimental, nonrandomized, nonequivalent, parallel group-controlled study involving before and after telephone surveys of the general population and postal surveys of general practitioners was conducted, with an adjacent state used as a control group. To evaluate the effectiveness of a population-based intervention designed to alter beliefs about back pain, influence medical management, and reduce disability and workers' compensation-related costs. A multimedia campaign begun during 1997 in Victoria, Australia, positively advised patients with back pain to stay active and exercise, not to rest for prolonged periods, and to remain at work. The campaign's impact on population beliefs about back pain and fear-avoidance beliefs was measured in telephone surveys, and the effect of the campaign on the potential management of low back pain by general practitioners was assessed by eliciting their likely approach to two hypothetical scenarios in mailed surveys. Demographically identical population groups in Victoria and the control state, New South Wales, were surveyed at three times: before, during, and after intervention in Victoria. The studies were completed by 4730 individuals in the general population and 2556 general practitioners. There were large statistically significant improvements in back pain beliefs over time in Victoria (mean scores on the Back Beliefs Questionnaire, 26.5, 28.4, and 29.7), but not in New South Wales (26.3, 26.2, and 26.3, respectively). Among those who reported back pain during the previous year, fear-avoidance beliefs about physical activity improved significantly in Victoria (mean scores on the Fear-Avoidance Beliefs Questionnaire for physical activity, 14, 12.5, and 11.6), but not in New South Wales (13.3, 13.6, and 12.7, respectively). General practitioners in Victoria reported significant improvements over time in beliefs about back pain management, as compared with their interstate colleagues. There were statistically significant interactions between state and time for 7 of 10 responses on management of acute low back pain, and for 6 of 10 responses on management of subacute low back pain. A population-based strategy of providing positive messages about back pain improves the beliefs of the general population and general practitioners about back pain and appears to influence medical management.

  5. 2001 Volvo Award Winner in Clinical Studies: Lumbar fusion versus nonsurgical treatment for chronic low back pain: a multicenter randomized controlled trial from the Swedish Lumbar Spine Study Group.

    Science.gov (United States)

    Fritzell, P; Hägg, O; Wessberg, P; Nordwall, A

    2001-12-01

    A randomized controlled multicenter study with a 2-year follow-up by an independent observer. To determine whether fusion of the lower lumbar spine could reduce pain and diminish disability more effectively when compared with nonsurgical treatment in patients with severe chronic low back pain (CLBP). The reported results after fusion surgery on patients with CLBP vary considerably, and the evidence of treatment efficacy is weak in the absence of randomized controlled studies. A total of 294 patients referred to 19 spinal centers from 1992 through 1998 were randomized blindly into four treatment groups. Patients aged 25-65 years with CLBP for at least 2 years and with radiologic evidence of disc degeneration at L4-L5, L5-S1, or both were eligible to participate in the study. The surgical group (n=222) included three different fusion techniques, not analyzed separately in this study. Patients in the nonsurgical group (n=72) were treated with different kinds of physical therapy. The surgical group comprised 49.5% men, and the mean age was 43 years. The corresponding figures for the nonsurgical group were 48.6% and 44 years. The patients had suffered from low back pain for a mean of 7.8 and 8.5 years and been on sick leave due to back pain for a mean of 3.2 and 2.9 years, respectively. The Visual Analogue Scale (VAS) was used to measure pain. The Oswestry Low Back Pain Questionnaire, the Million Score and the General Function Score (GFS) were used to measure disability. The Zung Depression Scale was used to measure depressive symptoms. The overall result was assessed by the patient and by an independent observer. Records from the Swedish Social Insurance were used to evaluate work disability. Patients who changed groups were included in the analyses of significance according to the intention-to-treat principle. At the 2-year follow-up 289 of 294 (98%) patients, including 25 who had changed groups, were examined. Back pain was reduced in the surgical group by 33% (64 to 43), compared with 7% (63 to 58) in the nonsurgical group (P=0.0002). Pain improved most during the first 6 months and then gradually deteriorated. Disability according to Oswestry was reduced by 25% (47 to 36) compared with 6% (48 to 46) among nonsurgical patients (P=0.015), according to Million by 28% (64 to 46) compared with 8% (66 to 60) (P=0.004), and accordingtoGFS by 31% (49 to 34) compared with 4% (48 to 46) (P=0.005). The depressive symptoms, according to Zung, were reduced by 20% (39 to 31) in the surgical group compared with 7% (39 to 36) in the nonsurgical group (P=0.123). In the surgical group 63% (122/195) rated themselves as "much better" or "better" compared with 29% (18/62) in the nonsurgical group (P<0.0001). The "net back to work rate" was significantly in favor of surgical treatment, or 36% vs. 13% (P=0.002). The early complication rate in the surgical group was 17%. Lumbar fusion in a well-informed and selected group of patients with severe CLBP can diminish pain and decrease disability more efficiently than commonly used nonsurgical treatment.

  6. A review of the 2001 Volvo Award winner in clinical studies: lumbar fusion versus nonsurgical treatment for chronic low back pain: a multicenter randomized controlled trial from the Swedish lumbar spine study group.

    Science.gov (United States)

    Kwon, Brian; Katz, Jeffrey N; Kim, David H; Jenis, Louis G

    2006-01-15

    The current debate over the efficacy of lumbar fusion for low back pain has not been settled. Fritzell et al published a landmark paper entitled "Lumbar fusion versus nonsurgical treatment for chronic low back pain: a multicenter randomized controlled trial from the Swedish lumbar spine study group." Their goal was to provide objective evidence supporting lumbar fusion. While it was well designed and important to our knowledge base, it has limitations. We set out to review their work in an unbiased yet critical manner. Our goals are to summarize the strengths and weaknesses of the paper, place it in the context of current knowledge, and highlight its significance for present-day practice and research. From technical and study design perspectives, Fritzell et al were able to validate the use of lumbar fusion for the treatment of low back pain. However, their use of "usual nonoperative" care and nonspecific definition of low back pain precluded a truly genuine comparison of operative and nonoperative groups. We commend the Swedish lumbar spine study group and their remarkable efforts; they elevated the sophistication of spine research and spawned many more excellent works to help settle the ongoing controversy on the ideal treatment of low back pain.

  7. 1997 Volvo Award winner in clinical studies. The effect of pedicle screw instrumentation on functional outcome and fusion rates in posterolateral lumbar spinal fusion: a prospective, randomized clinical study.

    Science.gov (United States)

    Thomsen, K; Christensen, F B; Eiskjaer, S P; Hansen, E S; Fruensgaard, S; Bünger, C E

    1997-12-15

    A prospective randomized clinical study. To evaluate supplementary pedicle screw fixation (Cotrel-Dubousset) in posterolateral lumbar spinal fusion. The rationale behind lumbar fusion is to eliminate pathologic motion to relieve pain. To improve fusion rates and to allow reduction, a rigid transpedicular screw fixation may be beneficial, but the positive effect of this may be counter-balanced by an increase in complications. The inclusion criteria were severe, chronic low back pain from spondylolisthesis Grades 1 and 2 or from primary or secondary degenerative segmental instability. One hundred thirty patients were randomly allocated to receive no instrumentation (n = 66) or Cotrel-Dubousset instrumentation (n = 64) in posterolateral lumbar fusion. Variables were registered at the time of surgery and at 1 and 2 years after surgery. Follow-up was achieved in 97.7% of the patients. Fusion rates deduced from plain radiographs were not significantly different between instrumented and noninstrumented groups. The functional outcome assessed by the Dallas Pain Questionnaire improved significantly in both groups, and there were no significant differences in results between the two groups, except for significantly better (P < 0.06) functional outcome in relation to daily activities in the instrumented group when neural decompression had been performed. The global patients' satisfaction was 82% in the instrumented group versus 74% in the noninstrumented group (not significant). Fixation of instrumentation increased operation time, blood loss, and early reoperation rate significantly. Patients experienced only a few minor postoperative complications; none were major. Two infections appeared in the Cotrel-Dubousset group. Significant symptoms from misplacement of pedicle screws were seen in 4.8% of the instrumented patients. Lumbar posterolateral fusion with pedicle screw fixation increases the operation time, blood loss, and reoperation rate, and leads to a significant risk of nerve injury. The functional outcome improves significantly with high patient satisfaction, with or without instrumentation. No significant differences were observed between the two groups in functional outcome and fusion rate. The only gain in functional outcome from instrumentation was found in the daily activity category in patients with supplementary neural decompression. The results of this study do not justify the general use of pedicle screw fixation alone as an adjunct to posterolateral lumbar fusion.

  8. A review of 1985 Volvo Award winner in clinical science: objective assessment of spine function following industrial injury: a prospective study with comparison group and 1-year follow-up.

    Science.gov (United States)

    Rainville, James; Kim, Richard S; Katz, Jeffrey N

    2007-08-15

    It is now 2 decades since Mayer et al published their Volvo Award-winning paper entitled "Objective assessment of spine function following industrial injury: a prospective study with comparison group and one-year follow-up." Their landmark paper reported that return to work rates of patients that underwent a "functional restoration" treatment program were double that of a comparative group of patients that were denied treatment by their insurers. These results were considered extraordinary and inspired both debate and enthusiasm. Our goal is to review this landmark study, report on its strengths and weaknesses, and review the studies that have attempted to replicate this work in other settings. We also highlight its contribution to our current knowledge about the treatment of back pain and disability. The major weaknesses of the paper of Mayer et al are the possibility of selection bias in the development of their cohort of patients and the lack of a true randomized controlled study design. These factors may have inflated the rates of return to work. Regardless, their reported results were robust, and cannot be easily dismissed. During the last 20 years, this treatment model has received considerable study worldwide, and it is generally agreed that it is superior to standard care for reducing work absence in patients with chronic low back pain. Additionally, the concepts underlying functional restoration have been found to be highly relevant to patients with chronic low back pain, medical providers, and disability systems and continue to gain acceptance and integration into the care of patients throughout the industrialized world.

  9. Practical aspects of informative providing organization of educational process in winner of the «Red Banner of Labour» award agro-industrial college of V.I. Vernadsky Crimean Federal University

    Directory of Open Access Journals (Sweden)

    Shengelay M.A.

    2016-12-01

    Full Text Available the article describes the modern stage of evolution of information management of educational process from classical paper-based libraries to modern digital ones. The principles of organization, advantages and disadvantages of web-based electronic information provision are characterized, it is shown how to design a digital library by the educational establishment.

  10. Escaping Adolescence: Sonya Hartnett's "Surrender" as a Gothic Bildungsroman for the Twenty-First Century: Winner of the 2016 Children's Literature in Education Emerging Scholar Award

    Science.gov (United States)

    Kealley, Adam

    2017-01-01

    This paper explores the subversion of the bildungsroman in the young adult novel, "Surrender" (Penguin, Camberwell, 2005), by the Australian author, Sonya Hartnett. It is suggested that, in reinscribing the traditional bildungsroman within a Gothic discourse, this novel reveals the effect on subjectivity that the horrors of postmodernity…

  11. Winner of the Lund Science Award 1992. Thermosensitization induced by step-down heating. A review on heat-induced sensitization to hyperthermia alone or hyperthermia combined with radiation.

    Science.gov (United States)

    Lindegaard, J C

    1992-01-01

    A few minute's exposure to a high temperature (sensitizing treatment, ST) may substantially increase the cytotoxic and the radiosensitizing effect of a subsequent heating at a lower temperature (test treatment, TT). This phenomenon, which is known as step-down heating (SDH) or thermosensitization, has been observed both in cultured cells in vitro and in tumours and normal tissues in vivo. The effect of SDH increases with a lowering of TT temperature, but it is rapidly lost at temperatures very close to 37 degrees C. SDH-induced thermosensitization decays within a few hours, when an interval is inserted between ST and TT. In vitro results suggest an exponential decay of the SDH effect with half times ranging from 1.5- to 3.1 h. The effect of SDH increases with increasing ST time or temperature. For single heating, the Arrhenius plot is biphasic with activation energies of 500-800 and 1200-1700 kJ/mol above and below a break point temperature in the region 42.5-43.0 degrees C, respectively. For SDH, the Arrhenius plot gradually becomes monophasic with increasing severity of ST and it approaches asymptotically to an activation energy of about 400 kJ/mol. The reduction of the activation energy depends on cell survival after the priming ST and not on the specific ST heating time or temperature. SDH strongly enhances hyperthermic radiosensitization with a 5-6-fold reduction of the radiation dose required to achieve tumour control. The thermosensitizing and the radiosensitizing effects of SDH have several features in common. Both effects become more prominent when the TT temperature is decreased and when the ST heating time or temperature increases. In addition, the decay kinetics for both effects are comparable. For heat alone, the effect of SDH in tumour and normal tissue seems to be quantitatively similar. However, the therapeutic ratio may be increased by combining SDH with radiation. Biologically, the critical subcellular targets involved in the SDH effect have not been revealed. However, the ability of SDH to inhibit the clearance of heat-induced aggregation of proteins in the nucleus is interesting. Blockage of the nuclear function by proteins is a central theory in the present molecular biological models for both cell kill by heat and heat radiosensitization. Clinically, SDH may be an advantage since even a short exposure to high temperature increases the effect of an otherwise inadequate heat treatment. The disadvantages are that SDH complicates thermal dose calculations, and may cause unacceptable damage to normal tissue.

  12. ``Models'' CAVEAT EMPTOR!!!: ``Toy Models Too-Often Yield Toy-Results''!!!: Statistics, Polls, Politics, Economics, Elections!!!: GRAPH/Network-Physics: ``Equal-Distribution for All'' TRUMP-ED BEC ``Winner-Take-All'' ``Doctor Livingston I Presume?''

    Science.gov (United States)

    Preibus-Norquist, R. N. C.-Grover; Bush-Romney, G. W.-Willard-Mitt; Dimon, J. P.; Adelson-Koch, Sheldon-Charles-David-Sheldon; Krugman-Axelrod, Paul-David; Siegel, Edward Carl-Ludwig; D. N. C./O. F. P./''47''%/50% Collaboration; R. N. C./G. O. P./''53''%/49% Collaboration; Nyt/Wp/Cnn/Msnbc/Pbs/Npr/Ft Collaboration; Ftn/Fnc/Fox/Wsj/Fbn Collaboration; Lb/Jpmc/Bs/Boa/Ml/Wamu/S&P/Fitch/Moodys/Nmis Collaboration

    2013-03-01

    ``Models''? CAVEAT EMPTOR!!!: ``Toy Models Too-Often Yield Toy-Results''!!!: Goldenfeld[``The Role of Models in Physics'', in Lects.on Phase-Transitions & R.-G.(92)-p.32-33!!!]: statistics(Silver{[NYTimes; Bensinger, ``Math-Geerks Clearly-Defeated Pundits'', LATimes, (11/9/12)])}, polls, politics, economics, elections!!!: GRAPH/network/net/...-PHYSICS Barabasi-Albert[RMP (02)] (r,t)-space VERSUS(???) [Where's the Inverse/ Dual/Integral-Transform???] (Benjamin)Franklin(1795)-Fourier(1795; 1897;1822)-Laplace(1850)-Mellin (1902) Brillouin(1922)-...(k,)-space, {Hubbard [The World According to Wavelets,Peters (96)-p.14!!!/p.246: refs.-F2!!!]},and then (2) Albert-Barabasi[]Bose-Einstein quantum-statistics(BEQS) Bose-Einstein CONDENSATION (BEC) versus Bianconi[pvt.-comm.; arXiv:cond-mat/0204506; ...] -Barabasi [???] Fermi-Dirac

  13. WE-G-18A-01: JUNIOR INVESTIGATOR WINNER - Low-Dose C-Arm Cone-Beam CT with Model-Based Image Reconstruction for High-Quality Guidance of Neurosurgical Intervention

    Energy Technology Data Exchange (ETDEWEB)

    Wang, A; Stayman, J; Otake, Y; Gallia, G; Siewerdsen, J [Johns Hopkins University, Baltimore, MD (United States)

    2014-06-15

    Purpose: To address the challenges of image quality, radiation dose, and reconstruction speed in intraoperative cone-beam CT (CBCT) for neurosurgery by combining model-based image reconstruction (MBIR) with accelerated algorithmic and computational methods. Methods: Preclinical studies involved a mobile C-arm for CBCT imaging of two anthropomorphic head phantoms that included simulated imaging targets (ventricles, soft-tissue structures/bleeds) and neurosurgical procedures (deep brain stimulation (DBS) electrode insertion) for assessment of image quality. The penalized likelihood (PL) framework was used for MBIR, incorporating a statistical model with image regularization via an edgepreserving penalty. To accelerate PL reconstruction, the ordered-subset, separable quadratic surrogates (OS-SQS) algorithm was modified to incorporate Nesterov's method and implemented on a multi-GPU system. A fair comparison of image quality between PL and conventional filtered backprojection (FBP) was performed by selecting reconstruction parameters that provided matched low-contrast spatial resolution. Results: CBCT images of the head phantoms demonstrated that PL reconstruction improved image quality (∼28% higher CNR) even at half the radiation dose (3.3 mGy) compared to FBP. A combination of Nesterov's method and fast projectors yielded a PL reconstruction run-time of 251 sec (cf., 5729 sec for OS-SQS, 13 sec for FBP). Insertion of a DBS electrode resulted in severe metal artifact streaks in FBP reconstructions, whereas PL was intrinsically robust against metal artifact. The combination of noise and artifact was reduced from 32.2 HU in FBP to 9.5 HU in PL, thereby providing better assessment of device placement and potential complications. Conclusion: The methods can be applied to intraoperative CBCT for guidance and verification of neurosurgical procedures (DBS electrode insertion, biopsy, tumor resection) and detection of complications (intracranial hemorrhage). Significant improvement in image quality, dose reduction, and reconstruction time of ∼4 min will enable practical deployment of low-dose C-arm CBCT within the operating room. AAPM Research Seed Funding (2013-2014); NIH Fellowship F32EB017571; Siemens Healthcare (XP Division)

  14. Student Award for Outstanding Research Winner in the Undergraduate Category for the 2017 Society for Biomaterials Annual Meeting and Exposition, April 5-8, 2017, Minneapolis, Minnesota: Development and characterization of stimuli-responsive hydrogel microcarriers for oral protein delivery.

    Science.gov (United States)

    O'Connor, Colleen; Steichen, Stephanie; Peppas, Nicholas A

    2017-05-01

    A family of pH-responsive terpolymers composed of methacrylic acid (MAA), N-vinyl pyrrolidone (NVP), and poly(ethylene glycol) monomethylether monomethacrylate (PEGMMA) have been developed and evaluated for their pH-responsive swelling behavior, protein-loading capabilities, and cytocompatibility. These terpolymer hydrogels, designated as P((MAA-co-NVP)-g-EG), were synthesized with varying PEG chain lengths and monomer feed ratios. The incorporation of MAA into the terpolymer structure was quantified with potentiometric titration. Equilibrium and dynamic swelling studies confirmed the pH-responsive behavior of the hydrogel, with the system remaining collapsed/complexed in acidic pH conditions and swollen/decomplexed in neutral pH conditions. The ability of the hydrogels to partition protein into the swollen network was assessed for two model proteins of varying molecular weight: insulin and porcine growth hormone. Finally, the cytocompatibility of the hydrogels in the presence of two model intestinal cell lines was investigated and confirmed minimal cytotoxicity at and below 2.5 mg/mL. The developed P((MAA-co-NVP)-g-EG) hydrogels exhibit unique properties that could potentially be utilized for drug delivery and separation applications. © 2017 Wiley Periodicals, Inc. J Biomed Mater Res Part A: 105A: 1243-1251, 2017. © 2017 Wiley Periodicals, Inc.

  15. ISSLS Prize winner: Long-term follow-up suggests spinal fusion is associated with increased adjacent segment disc degeneration but without influence on clinical outcome: results of a combined follow-up from 4 randomized controlled trials.

    Science.gov (United States)

    Mannion, Anne F; Leivseth, Gunnar; Brox, Jens-Ivar; Fritzell, Peter; Hägg, Olle; Fairbank, Jeremy C T

    2014-08-01

    Cross-sectional analysis of long-term follow-up (LTFU) data from 4 randomized controlled trials of operative versus nonoperative treatment for chronic low back pain. To examine the influence of spinal fusion on adjacent segment disc space height as an indicator of disc degeneration at LTFU. There is ongoing debate as to whether adjacent segment disc degeneration results from the increased mechanical stress of fusion. Plain standing lateral radiographs were obtained at LTFU (mean, 13 ± 4 yr postrandomization) in 229 of 464 (49%) patients randomized to surgery and 140 of 303 (46%), to nonoperative care. Disc space height and posteroanterior displacement were measured for each lumbar segment using a validated computer-assisted distortion compensated roentgen analysis technique. Values were reported in units of standard deviations above or below age and sex-adjusted normal values. Patient-rated outcomes included the Oswestry Disability Index and pain scales. Radiographs were usable in 355 of 369 (96%) patients (259 fusion and 96 nonoperative treatment). Both treatment groups showed significantly lower values for disc space height of the adjacent segment than norm values. There was a significant difference between treatment groups for the disc space height of the cranial adjacent segment (in both as-treated and intention-to-treat analyses). The mean treatment effect of fusion on adjacent segment disc space height was -0.44 SDs (95% CI, -0.77 to -0.11; P = 0.01; as-treated analysis); there was no group difference for posteroanterior displacement (0.18 SDs, 95% confidence interval, -0.28 to 0.64, P = 0.45). Adjacent level disc space height and posteroanterior displacement were not correlated with Oswestry Disability Index or pain scores at LTFU (r = 0.010-0.05; P > 0.33). Fusion was associated with lower disc space height at the adjacent segment after an average of 13 years of FU. The reduced disc space height had no influence on patient self-rated outcomes (pain or disability). 2.

  16. Increased gait variability may not imply impaired stride-to-stride control of walking in healthy older adults: Winner: 2013 Gait and Clinical Movement Analysis Society Best Paper Award.

    Science.gov (United States)

    Dingwell, Jonathan B; Salinas, Mandy M; Cusumano, Joseph P

    2017-06-01

    Older adults exhibit increased gait variability that is associated with fall history and predicts future falls. It is not known to what extent this increased variability results from increased physiological noise versus a decreased ability to regulate walking movements. To "walk", a person must move a finite distance in finite time, making stride length (L n ) and time (T n ) the fundamental stride variables to define forward walking. Multiple age-related physiological changes increase neuromotor noise, increasing gait variability. If older adults also alter how they regulate their stride variables, this could further exacerbate that variability. We previously developed a Goal Equivalent Manifold (GEM) computational framework specifically to separate these causes of variability. Here, we apply this framework to identify how both young and high-functioning healthy older adults regulate stepping from each stride to the next. Healthy older adults exhibited increased gait variability, independent of walking speed. However, despite this, these healthy older adults also concurrently exhibited no differences (all p>0.50) from young adults either in how their stride variability was distributed relative to the GEM or in how they regulated, from stride to stride, either their basic stepping variables or deviations relative to the GEM. Using a validated computational model, we found these experimental findings were consistent with increased gait variability arising solely from increased neuromotor noise, and not from changes in stride-to-stride control. Thus, age-related increased gait variability likely precedes impaired stepping control. This suggests these changes may in turn precede increased fall risk. Copyright © 2017 Elsevier B.V. All rights reserved.

  17. MedlinePlus: Awards and Recognition

    Science.gov (United States)

    ... winner of the 2005 World Summit on the Information Society Awards for e-health. Winner of the Thomas Reuters/Frank Bradway Rogers Information Advancement Award in 2014 for MedlinePlus Connect and ...

  18. 77 FR 26015 - Announcement of Requirements and Registration for “Seeing My World through a Safer Lens: What...

    Science.gov (United States)

    2012-05-02

    ... outside the scope of their employment should consult their ethics official prior to developing their..., finalists, and winners of the Contest. Information is not collected for commercial marketing. Winners are...

  19. Sexospécificités | Page 196 | CRDI - Centre de recherches pour le ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    -urban South Asia and find fair and sustainable solutions. ... Yoseth Ariza Araύjo, Sarah Olson, and Coll Hutchison, winners of the Student Poster Awards, and Dr Susilowati Tana, Ecohealth Research Presentation Award winner, were all ...

  20. Voting paradoxes and group coherence the condorcet efficiency of voting rules

    CERN Document Server

    Gehrlein, William V

    2011-01-01

    This book argues that strange election outcomes should become less likely as voters' preferences become more mutually coherent. It also focuses on the Condorcet Criterion, which states that pairwise majority rule winner should be chosen as the election winner.

  1. "Be Sickle Smart!" | NIH MedlinePlus the Magazine

    Science.gov (United States)

    ... Table of Contents Singing star and former American Idol winner Ruben Studdard wrote the song,"I Am ... sickle cell disease Recording artist and former American Idol winner Ruben Studdard has made the fight against ...

  2. ATLAS Thesis Awards 2015

    CERN Multimedia

    Biondi, Silvia

    2016-01-01

    Winners of the ATLAS Thesis Award were presented with certificates and glass cubes during a ceremony on Thursday 25 February. The winners also presented their work in front of members of the ATLAS Collaboration. Winners: Javier Montejo Berlingen, Barcelona (Spain), Ruth Pöttgen, Mainz (Germany), Nils Ruthmann, Freiburg (Germany), and Steven Schramm, Toronto (Canada).

  3. Notes on Calvin’s knowledge, use, and misuse of the Church Fathers

    Directory of Open Access Journals (Sweden)

    Johannes van Oort

    2015-09-01

    Full Text Available John Calvin (1509–1564 started his career as a thoroughly trained humanist who possessed, in addition, a thorough knowledge of the Fathers of the Church. This article provides an overview of this particular knowledge. It also focuses on the use Calvin made of the patristic argument in both his instructive and apologetic writings. Some evident cases of Calvin’s misuse of the patres are discussed as well. It is concluded that Calvin’s special patristic knowledge gave his theology its special hallmark and still links authentic Calvinism with the church’s catholic tradition through the ages.

  4. USA sõjaväeluurijad kuulavad süütute mõrvas kahtlustatavat / Evelyn Kaldoja

    Index Scriptorium Estoniae

    Kaldoja, Evelyn, 1980-

    2010-01-01

    USA seersanti Calvin R. Cibbsi kahtlustatakse afgaani tsiviilisikute tapmises, nende kehaosade kogumises trofeedena, kanepi suitsetamises. USA sõjavägi vaatab üle kõiki temaga seotud surmade asjaolusid

  5. Kto jest kto v mire sovremennoi modõ

    Index Scriptorium Estoniae

    2002-01-01

    Tutvustatakse kaasaja kuulsaid moekunstnikke: Alexander McQueen (s. 1970 Londonis), Calvin Klein (1942), Christian Lacroix (1951), Cindy Crawford (1966), Domenico Dolce (1958 Sitsiilias), Stefano Gabbana (1962 Veneetsias). Järgneb

  6. FROGS Report Friends of Granite Summer 1989

    Science.gov (United States)

    FROGS Reports present information on current research relevant to felsic magmatism, including commentaries on problems of current interest. Please contact Calvin Miller (6028B, Vanderbilt University, Nashville, TN 37235) concerning your own research, conferences, and ideas for stimulating commentaries.

  7. Calvyn en die Calvinisme | Engelbrecht | HTS Teologiese Studies ...

    African Journals Online (AJOL)

    Calvinism, the Social Gospel, the rationalistic Orthodoxism, the methodistic Pietism, the Enlightenment, theological Liberalism and modem hermeneutics are broached. Finally, ensuing from this, the most important issues to be adrcssed presently in ...

  8. An ethnobotanical study of medicinal plants used in villages under ...

    African Journals Online (AJOL)

    An ethnobotanical study of medicinal plants used in villages under Jongilanga Tribal Council, Mpumalanga, South Africa. Thilivhali Emmanuel Tshikalange, Boikanyo Calvin Mophuting, James Mahore, Stefan Winterboer, Namrita Lall ...

  9. Conversio Ad Docelitam: Calvyn oor bekering en Christenwees

    Directory of Open Access Journals (Sweden)

    Wim A. Dreyer

    2014-09-01

    Full Text Available Conversio ad docelitam: John Calvin on conversion and being a Christian. This contribution describes John Calvin’s understanding of what it means to be a Christian. When Calvin ‘converted’ to the Reformation in the early 1530s, the term ‘Protestant’ did not exist. There was no systematic body of doctrine or a confession you could put your signature under. So Calvin became a ‘lover of Christ’. The unity with Christ was a central part of his theology but also his personal spirituality. Calvin also understood his own conversion as a ‘conversio subita ad docelitam’, a conversion to a ‘teachable frame of mind’. Calvin’s love for Christ, his love for the Word of God and a teachable frame of mind not only defined his theology, but also his piety and spirituality.

  10. CrossTalk: The Journal of Defense Software Engineering. Volume 21, Number 9

    National Research Council Canada - National Science Library

    Cook, Steve; Lin, Calvin; Chang, Walter; Hansson, Joergen; Feiler, Peter H; Morley, John; Howard, Michael; Pal, Partha; Atighetchi, Michael; Goertzel, Karen M; Cunha, Corey P

    2008-01-01

    .... Calvin Lin, and Walter Chang: Describes an extensible, compiler-based system to ensure that C programs enforce a wide variety of user-defined security policies with a minimum of runtime overhead and disruption to development processes. 2...

  11. Coast Guard Polar Icebreaker Modernization: Background and Issues for Congress

    Science.gov (United States)

    2016-05-27

    subcommittee of the House Transportation and Infrastructure Committee, Vice Admiral John P. Currier, the Vice Commandant of the Coast Guard, testified...55 Calvin Biesecker, “Coast Guard Requests Information On Heavy Polar Icebreaker,” Defense...

  12. 75 FR 44049 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2010-07-27

    ... the twenty-five exemption applications, FMCSA exempts, Calvin R. Adams, Michael R. Amstutz, Clinton R..., Scott D. Endres, Michael H. Hayden, Jarvis D. Hubbell, John T. Jones, Blake A. S. Keeten, Randall L...

  13. The Crow Creek Site (39BF11) Massacre: A Preliminary Report,

    Science.gov (United States)

    1981-02-01

    to individual vertebrae or groups of vertebrae, but nothing was found which suggested ankylosing spondylitis . Classical Marie-Strumple disease has been...preferentially take up 12C over 13C from their immediate environments in order to metabolize energy through three major pathways : C3 (Calvin), C4 (Hatch...Slack), and CAM (Crassulacean Acid Metabolism) (Throughton 1972). Most non- desert plants have the Calvin or C3 pathway with a 3-carbon struc- 300

  14. From Noyon to Geneva

    Directory of Open Access Journals (Sweden)

    W.A. Dreyer

    2010-07-01

    Full Text Available This article contains a brief biography of John Calvin. It serves as an introduction to the publication of the Conventus Reformatus on the occasion of celebrating Calvin’s birth 500 years ago. The article follows Calvin’s life, from his birth in Noyon until his death in Geneva. The focus is on persons and events which had a substantial influence on Calvin. Calvin’s theology is discussed in other contributions in this publication.

  15. Army Medical Imaging System - ARMIS

    Science.gov (United States)

    1992-08-08

    Melvin P. Siedband Frank C. Grenzow Craig A. Heilman James R. Gray Huilian Zhang A ... NTtS CFA?•I " U ; J C l A t j. University of Wisconsin _. I e...Medical Imaging System - ARMIS Contract # 6.AUTHOR(S) Melvin P. Siedband James R. Gray DAMDI7-88C-8058 Frank C. Grenzow Huilian Zhang 63807A Craig A...its use is inconsistent to the people who must manage it. The consistency of the Macin- tosh operating system permits easier staff training as imaging

  16. Consuming the Body of Christ in John Calvin’s Eucharistic Theology

    Directory of Open Access Journals (Sweden)

    Vladimir Drobot

    2015-02-01

    Full Text Available Contemporary Western scholars commenting on Calvin usually concentrate on his use of the concept of communion with Christ as a communion which takes effect solely through the means of grace. The author of this article, however, examines Calvin’s views through the prism of his idea of divine sovereignty - an integral part of his theology. This necessarily diminishes the theological basis for the incarnation, and this comes out clearly in the way Calvin discusses a type of communion with Christ in the Old Testament and outside the Eucharistic sacrament. Primarily, Calvin views the Eucharist as a vivid narrative centering on Christ and His Sacrifice, and only secondarily as an independent reality. The author argues that Calvin did not think that the faithful received the concrete body of Christ in both soul and body during Holy Communion. Calvin’s doctrine of Eucharistic consummation is confined to a spiritual dimension and his use of a kind of realism when discussing the Eucharist should be figuratively understood as a use of metonymy. When Calvin speaks about the Body of Christ in the context of the Eucharist, he metonymically means the life-giving grace of Christ. The Body of Christ is seen by Calvin as a type of conduit which transfers Christ’s spiritual gifts or graces to the faithful. Calvin’s rare statements about the transformation of the body of the communicant should be understood in an eschatological perspective as referring to the resurrection of the body on the Last Day.

  17. The Triune God who speaks: Calvin’s theological hermeneutics

    Directory of Open Access Journals (Sweden)

    J.B. Krohn

    2001-08-01

    Full Text Available The purpose of this article is to make a contribution to the theme of “Calvin as servant of the Word” by exploring some hermeneutical implications of Calvin’s theological commitment to the doctrine of God as Triune. In doing so, it seeks to follow a hermeneutical principle Calvin himself held, that Biblical interpretation had to pass through three distinct but related phases; exegesis (represented by his commentaries, dogmatics (represented by the Institutes, and preaching (represented by his sermons. For Calvin, if any of these phases were omitted, the text would not be interpreted properly, and the message of Scripture would not rightly be applied to the life of the church. The place and importance of the doctrine of the Trinity in Calvin’s theology (often neglected in Calvin scholarship are first explored, followed by displaying the importance Calvin attached to the integration of doctrine into the hermeneutical process (often disregarded by modern-day exegetes, and finally, all three phases of the interpretational process are brought to bear on Calvin’s sermonic treatment of John 1:1-5. Through expository preaching of the Scriptures, hermeneutics finds its completion, and believers will have a personal encounter with God. As such, Calvin will be shown to be a most excellent servant of the Word.

  18. The LSR/2 Optically Coupled Signal Transmission Link.

    Science.gov (United States)

    1979-12-01

    PARK ATTN DR. SHERMAN KARP ATTN DR. MELVIN L. PRICE, MS-44 ARCHITECT BLDG HUNTSVILLE, AL 35807 1400 WILSON BLVD ARLINGTON, VA 22209 ENGINEERING...COMMANDER ATTN EL, ELECTRONICS DIV NAVAL WEAPONS CENTER ATTN COL GERALD P. CHAPMAN ATTN 315, LASER/INFRARED SYS DIV KIRTLAND AFB, NM 87117 ATTN 394

  19. Saudi Arabia: The Fulcrum of U.S. National Security in Southwest Asia.

    Science.gov (United States)

    1988-04-01

    BIBLIOGRAPHY A. REFERENCES CITED Books 1. Campbell, John C. "The Middle East: A House of containment Built on Shifting Sands." National Security Manangment ...Fouad A. "Saudi-American Relations in a Changing World." American-Arab Affairs, Winter 1986-7. 5. Conant, Melvin A. "Recognizing U.S.-Arab

  20. Law of Federal Employment

    Science.gov (United States)

    2000-09-01

    Department of Corrections and Human Resources (MDCHR). Respondent Melvin Hicks, a black man, was hired as a correctional officer at St. Mary’s in...demoted from shift commander to correctional officer for his failure to ensure that his subordinates entered their use of a St. Mary’s vehicle into

  1. Law of Federal Employment. Revised

    Science.gov (United States)

    1998-07-01

    Melvin Hicks, a black man, was hired as a correctional officer at St. Mary’s in August 1978 and was promoted to shift commander, one of six...brawl between inmates that occurred during his shift on March 21. He was later demoted from shift 9-18 commander to correctional officer for

  2. West Indian Gallery

    Science.gov (United States)

    Ramsaran, J. A.

    1975-01-01

    Reviews the poetry of Derek Walcott, a native of the West Indies, whose new volume 'Another Life' more resembles the poet-artists commentary on a gallery of scenes and portraits in Melvin Tolson's 'The Harlem Gallery' than anything else that has come from the English speaking Caribbean in the post-war period. (Author/JM)

  3. Paradoxical Pathways: An Ethnographic Extension of Kohn's Findings on Class and Childrearing

    Science.gov (United States)

    Weininger, Elliot B.; Lareau, Annette

    2009-01-01

    Stratification is a central issue in family research, yet relatively few studies highlight its impact on family processes. Drawing on in-depth interviews (N = 137) and observational data (N = 12), we extend Melvin Kohn's research on childrearing values by examining how parental commitments to self-direction and conformity are enacted in daily…

  4. Development and Validation of Methods for Applying Pharmacokinetic Data in Risk Assessment. Volume 3. Tetrachloroethylene

    Science.gov (United States)

    1990-12-01

    Armstrong Aerospace Medical Research Laboratory, Wright Paterson Air Force Base, and Drs. Melvin Andersen and Michael Cargas , formerly with the Harry G...Department of Labor . Contract 41USC252C3. Ikeda, M. (1977). Metabolism of trichloroethylene and tetrachloroethylene in human subjects. Environ Health

  5. 76 FR 48863 - Renewal of Charter for the Presidential Advisory Council on HIV/AIDS

    Science.gov (United States)

    2011-08-09

    ... on HIV/ AIDS AGENCY: Department of Health and Human Services, Office of the Secretary, Office of the Assistant Secretary for Health, Office of HIV/ AIDS Policy. ACTION: Notice. SUMMARY: The Department of... on HIV/ AIDS (PACHA; the Council) has been renewed. FOR FURTHER INFORMATION CONTACT: Mr. Melvin Joppy...

  6. Luuleõhtu "Sitikas suudleb kuud"

    Index Scriptorium Estoniae

    2009-01-01

    29. okt. toimub Adamson-Ericu muuseumis luuleõhtu, kus esinevad Andres Ehin luule ja häälutustega, Mart Soo kitarril ja Brian Melvin löökriistadel. Üritus toimub Kōkyō Hatanaka (sünd. 1947) näituse "Aasia minu südames. Jaapani klassikaline maal nihonga" raames

  7. 78 FR 22596 - Qualification of Drivers; Exemption Applications; Vision

    Science.gov (United States)

    2013-04-16

    ...) Wesley J. Jenkins (IL) Francisco J. Jimenez (TX) Christopher J. Kane (VT) Kenneth C. Keil (CA) Melvin A. Kleman (OH) Michael Lafferty (ID) Roosevelt Lawson (AL) Eugene R. Lydick (VA) Emanuel N. Malone (VA.... Riendeau (ND) James A. Smith (WA) Clarence L. Swann, Jr. (AL) Michael G. Trueblood (IL) Donald A. Uplinger...

  8. Chinese human smuggling in transit

    NARCIS (Netherlands)

    Soudijn, Melvin Roan Jasper

    2006-01-01

    Kleinschalige mensensmokkelaars beheersen de gehele smokkelroute van China naar de eindbestemming, grootschalige smokkelaars beheersen paradoxaal genoeg slechts een gedeelte van het traject. Dat is een van de conclusies uit de dissertatie “Chinese Smuggling in Transit” van Melvin Soudijn. Het

  9. Proceedings of Cabin Safety Conference and Workshop Held on December 11-14, 1984.

    Science.gov (United States)

    1985-08-01

    DC 20005 National Business Aircraft " ", One Farragut Square South •Washington, DC 20006 "* (202) 783-9000 204 1% -- Erich Feldkirchner Francesco...214) 358-9242 Blagnac, France 31700 6010-3050 Lucien Gormont (61) 93.36.30 William R. Fromme International Technical Staff Melvin Fielder Director of

  10. Trainable Mentally Impaired/Severely Multiply Impaired/Autistic Impaired/Severely Mentally Impaired. Product Evaluation Report 1989-1990.

    Science.gov (United States)

    Claus, Richard N.; And Others

    The evaluation report describes special education services provided to trainable mentally impaired (TMI), autistic impaired (AI), severely multiply impaired (SXI), and severely mentally impaired (SMI) students at and through the Melvin G. Millet Learning Center (Bridgeport, Michigan). The eight program components are described individually and…

  11. Avignoni totaalne teatrifestival / Andres Keil

    Index Scriptorium Estoniae

    Keil, Andres, 1974-

    2007-01-01

    Avignoni teatrifestivalil nähtust. Lähemalt Marc Wolters'i ühemeheteater "Colt Warmers", Chapelle Sainte Claire (Alfred Jarry) "Kuningas Ubu", Herman Hesse "Sidharta" mängituna India teatritrupi poolt, "Movin' Melvin Brown : Me, Ray Charles and Sammy D. Jr" ning Virgine Mirabeau koreograafial tantsuetendus "Shoult I Stay Or..." Art's Fusion esituses

  12. Creativity, Spirituality, and Transcendence: Paths to Integrity and Wisdom in the Mature Self. Publications in Creativity Research.

    Science.gov (United States)

    Miller, Melvin E., Ed.; Cook-Greuter, Susanne R., Ed.

    This book contains 11 papers on creativity, spirituality, and transcendence as paths to integrity and wisdom in the mature self. The book begins with the paper "Introduction--Creativity in Adulthood: Personal Maturity and Openness to Extraordinary Sources of Inspiration" (Susanne R. Cook-Greuter, Melvin E. Miller). The next four papers,…

  13. Promotion of good governance and combating corruption and ...

    African Journals Online (AJOL)

    Melvin Mbao and G.G Komboni criticise the legal regime and institutional arrangements designed to promote good government and to combat corruption and maladministration in Botswana, a country widely acclaimed as Africa's success story. Using internationally accepted benchmarks on good governance and combating ...

  14. H-60A/L Passenger Airbag Protection: Vertical and Horizontal Impact Tests

    Science.gov (United States)

    2013-04-30

    upper attachments points were modified to ensure they did not disconnect during the tests. Tie wraps were used to secure down the release levers and...Melvin, J., Stanaker, R. et al., "Size, Weight and Biomechanical Impact Response Requirements for Adult Size Small Female and Large Male Dummies," SAE

  15. Ängist kirgastumiseni / Aita Kivi

    Index Scriptorium Estoniae

    Kivi, Aita, 1954-

    2000-01-01

    Sisu : Frank McCourt. Jah, on küll; Kaur Kender. Ebanormaalne; Arnon Grunberg. Helesinised esmaspäevad; Melvin Burgess. Saast; Louis de Bernières. Kapten Corelli mandoliin; Jaergen-Frantz Jacobsen. Barbara; Jayne Ann Krentz. Sügavad veed; Enno Tammer. Uppumatu Estonia

  16. Bribery: Greed versus reciprocity

    OpenAIRE

    Gneezy, Uri; Saccardo, Silvia; van Veldhuizen, Roel

    2016-01-01

    It is estimated that a trillion dollars are annually exchanged in bribes, distorting justice and economic efficiency. In a novel experiment, we investigate the drivers of bribery. Two participants compete for a prize; a referee picks the winner. Participants can bribe the referee. When the referee can keep only the winner's bribe, bribes distort her judgment. When the referee keeps the bribes regardless of the winner, bribes no longer influence her judgment. An extra-laboratory experiment in ...

  17. Presidential Green Chemistry Challenge: 2009 Academic Award

    Science.gov (United States)

    Presidential Green Chemistry Challenge 2009 award winner, Professor Krzysztof Matyjaszewski, developed Atom Transfer Radical Polymerization to make polymers with copper catalysts and environmentally friendly reducing agents.

  18. Presidential Green Chemistry Challenge: 2010 Designing Greener Chemicals Award

    Science.gov (United States)

    Presidential Green Chemistry Challenge 2010 award winner, Clarke, developed Natular, a plaster matrix that encapsulates the pesticide spinosad, slowly releasing it into water and effectively controlling mosquito larvae.

  19. Presidential Green Chemistry Challenge: 2014 Designing Greener Chemicals Award

    Science.gov (United States)

    Presidential Green Chemistry Challenge 2014 award winner, The Solberg Company, replaced fluorinated surfactants in its firefighting foam concentrates with a blend of non-fluorinated surfactants and sugars.

  20. Presidential Green Chemistry Challenge: 2001 Small Business Award

    Science.gov (United States)

    Presidential Green Chemistry Challenge 2001 award winner, EDEN Bioscience, discovered and commercialized harpins: nontoxic, naturally occurring, biodegradable proteins that activate a plant's defense and growth mechanisms.

  1. Presidential Green Chemistry Challenge: 2005 Designing Greener Chemicals Award

    Science.gov (United States)

    Presidential Green Chemistry Challenge 2005 award winner, Archer Daniels Midland, developed Archer RC, a nonvolatile, biobased, reactive coalescent that replaces volatile organic coalescents in architectural latex paints.

  2. Presidential Green Chemistry Challenge: 2014 Greener Synthetic Pathways Award

    Science.gov (United States)

    Presidential Green Chemistry Challenge 2014 award winner, Solazyme, engineered microalgae to produce oils tailored to customers’ needs that can mimic or enhance properties of traditional vegetable oils.

  3. Presidential Green Chemistry Challenge: 2007 Greener Reaction Conditions Award

    Science.gov (United States)

    Presidential Green Chemistry Challenge 2007 award winner, Headwaters Technology Innovation, developed a metal nanocatalyst to synthesize hydrogen peroxide directly from hydrogen and oxygen, eliminating hazardous chemicals.

  4. Presidential Green Chemistry Challenge: 2004 Greener Reaction Conditions Award

    Science.gov (United States)

    Presidential Green Chemistry Challenge 2004 award winner, Buckman Laboratories International, developed Optimyze technology, which uses an esterase enzyme to remove sticky contaminants from paper products prior to recycling.

  5. Surgery on Fetus Reduces Complications of Spina Bifida

    Medline Plus

    Full Text Available ... Snapshot of Pregnancy & Infant Development Advances Snapshot of Child Development Advances Snapshot of Adult & Family Health Advances NICHD Nobel Prize Winners Leadership & Other ...

  6. 2004 Small Business Award

    Science.gov (United States)

    Presidential Green Chemistry Challenge 2004 award winner, Jeneil Biosurfactant Company, makes biobased, rhamnolipid surfactants by fermentation that are less toxic and more biodegradable than conventional surfactants.

  7. Chico Pereira, Ganador del Premio Cinematográfico de la Agencia Europea para la Seguridad y la Salud en el Trabajo con el largometraje "El Invierno de Pablo" The Film "Pablo's Winter" of Chico Pereira, Winner of the film award fron the European Agency for Safety and Health at Work

    Directory of Open Access Journals (Sweden)

    María Dolores Limón Tamés

    2012-12-01

    Full Text Available La Agencia Europea para la Seguridad y la Salud en el Trabajo (EU-OSHA organiza cada año el Festival de Cine Documental de Leipzig (DOK, Leipzig en el que se otorga el Premio Cinematográfico "Lugares de Trabajo Saludables" al documental que destaque como promotor del debate y la reflexión entre los ciudadanos europeos sobre la importancia de la seguridad y la salud en el trabajo. Este año 2012, el Premio ha sido otorgado al largometraje "El invierno de Pablo" del director español Chico Pereira, que narra la cruda historia de Pablo, un minero jubilado que trabajó extrayendo cinabrio durante 30 años y que actualmente presenta unos pulmones y un corazón seriamente dañados como consecuencia de la continua exposición al sulfuro de mercurio. En España, la Red Española de Seguridad y Salud en el Trabajo, coordinada por el Instituto Nacional de Seguridad e Higiene en el Trabajo, organizará durante 2013 sesiones de cine forum en la que se podrán visionar las películas ganadoras del Certamen Cinematográfico "Lugares de Trabajo Saludables", como actividad divulgativa para el debate y la promoción de la cultura preventiva.The European Agency for Safety and Health at Work (EU-OSHA is supporting every year the Healthy Workplaces Film Award for the best documentary on work-related topics. The award is presented at the International Leipzig Festival for Documentary and Animated Film (DOK Leipzig. The award honours a documentary film that promotes the importance of workplace health and safety across Europe. The film "Pablo's Winter" won this year the edition, telling the story of a retired miner who had been working during 30 years in an old mercury mine in Spain and currently has his heart and lungs severely damaged as a result of continued exposure to mercury sulfide. In Spain, the Spanish Network of Safety and Health at Work, coordinated by the National Institute of Safety and Health at Work, is organizing during 2013 video screenings of documentary films awarded, as an activity for promoting health and safety at work to encourage preventive culture. Key words: Human Rights, Copyright, authorship, Open Access, Creative Commons.

  8. RSJ/CCCU Article Prize Winner: "The Infanta will marry the person who provides the Peace or the one who gives us the means to continue the War”. The negotiations for the marriage between Infanta María Teresa of Austria and Emperor Leopold I (1654-1657.

    Directory of Open Access Journals (Sweden)

    Rocío Martínez López

    2016-06-01

    Full Text Available Prince Baltasar Carlos’s death in 1646 turned his little sister, María Teresa, into the direct heiress of King Felipe IV of Spain. For this reason, her marriage became a key issue regarding the European politics of the central decades of the seventeenth century. Her marriage with the heir of Emperor Ferdinand III was the option chosen by Felipe IV as the most convenient for his territories as long as there was no male heir for his throne. But the negotiations to achieve that end were far from easy. In this essay, we will examine the negotiations conducted between Madrid and Vienna during the years 1654 and 1657, to arrange the marriage between Infanta María Teresa and the future emperor Leopold I, through the correspondence interchanged between King Felipe IV and his ambassadors in the imperial court..

  9. I. 'Street of twins': multiple births in Cuba II. The Cuban twin registry: an update / twin research reports: cord entanglement; heritability of clubfoot; school separation / twins and twin researchers in the news: reunited at seventy-eight; basketball duo dissolved; delivered holding hands; the better brew; award winners.

    Science.gov (United States)

    Segal, Nancy L; Marcheco-Teruel, Beatriz

    2014-08-01

    I was part of a people-to-people tour of Havana, Cuba during the first week in April 2014. Among the many highlights of that adventure were an informal meeting with Dr Beatriz Marcheco-Teruel, from Cuba's National Center for Medical Genetics, and a visit to the famous 'Street of Twins'. A fortuitous meeting with parents of twins in the fishing town of Jaimanitas was also an extraordinary event. The Cuban experience is followed by summaries of recent twin research, covering umbilical cord entanglement, the heritability of clubfoot and school separation policies for twins. Media reports include twins reunited at age 78, the future of UCLA's twin basketball players, MZ twins born holding hands, a twin conflict over beer and a pair of American Psychological Association honors for Drs Nancy L. Segal and Thomas J. Bouchard, Jr.

  10. Student award winner in the Ph.D. category for the 2013 society for biomaterials annual meeting and exposition, april 10-13, 2013, Boston, Massachusetts : biomaterial-mediated cancer-specific DNA delivery to liver cell cultures using synthetic poly(beta-amino ester)s.

    Science.gov (United States)

    Tzeng, Stephany Y; Higgins, Luke J; Pomper, Martin G; Green, Jordan J

    2013-07-01

    Liver cancer is a leading cause of cancer death. Most patients are treated by arterial injection of chemoembolizing agents, providing a convenient avenue for local treatment by novel therapies, including gene therapy. Poly(beta-amino ester)s (PBAEs) were synthesized and used to form nanoparticles for non-viral transfection of buffalo rat hepatoma (MCA-RH7777) and hepatocyte (BRL-3A) lines with eGFP and luciferase DNA. Hepatoma cells were transfected with up to (98 ± 0.4)% efficacy with no measurable cytotoxicity. Hepatocytes were transfected with as high as (73 ± 0.4)% efficacy with (10 ± 4)% non-specific cytotoxicity. In contrast, positive controls (branched polyethylenimine, Lipofectamine™ 2000, and X-tremeGENE(®) DNA HP) caused 30-90% toxicity in BRL-3A cells at doses required for >50% transfection. Of the 21 optimized PBAE-DNA formulations tested, 12 showed significant specificity for hepatoma cells over hepatocytes in monoculture (p biomaterial-mediated specificity to prevent toxic side-effects on healthy hepatocytes. Copyright © 2013 Wiley Periodicals, Inc.

  11. Student award for outstanding research winner in the Ph.D. category for the 2017 society for biomaterials annual meeting and exposition, april 5-8, 2017, Minneapolis, Minnesota: Characterization of protein interactions with molecularly imprinted hydrogels that possess engineered affinity for high isoelectric point biomarkers.

    Science.gov (United States)

    Clegg, John R; Zhong, Justin X; Irani, Afshan S; Gu, Joann; Spencer, David S; Peppas, Nicholas A

    2017-06-01

    Molecularly imprinted polymers (MIPs) with selective affinity for protein biomarkers could find extensive utility as environmentally robust, cost-efficient biomaterials for diagnostic and therapeutic applications. In order to develop recognitive, synthetic biomaterials for prohibitively expensive protein biomarkers, we have developed a molecular imprinting technique that utilizes structurally similar, analogue proteins. Hydrogel microparticles synthesized by molecular imprinting with trypsin, lysozyme, and cytochrome c possessed an increased affinity for alternate high isoelectric point biomarkers both in isolation and plasma-mimicking adsorption conditions. Imprinted and non-imprinted P(MAA-co-AAm-co-DEAEMA) microgels containing PMAO-PEGMA functionalized polycaprolactone nanoparticles were net-anionic, polydisperse, and irregularly shaped. MIPs and control non-imprinted polymers (NIPs) exhibited regions of Freundlich and BET isotherm adsorption behavior in a range of non-competitive protein solutions, where MIPs exhibited enhanced adsorption capacity in the Freundlich isotherm regions. In a competitive condition, imprinting with analogue templates (trypsin, lysozyme) increased the adsorption capacity of microgels for cytochrome c by 162% and 219%, respectively, as compared to a 122% increase provided by traditional bulk imprinting with cytochrome c. Our results suggest that molecular imprinting with analogue protein templates is a viable synthetic strategy for enhancing hydrogel-biomarker affinity and promoting specific protein adsorption behavior in biological fluids. © 2017 Wiley Periodicals, Inc. J Biomed Mater Res Part A: 105A: 1565-1574, 2017. © 2017 Wiley Periodicals, Inc.

  12. Winner of the society for biomaterials student award in the Ph.D. category for the annual meeting of the society for biomaterials, april 11-14, 2018, Atlanta, GA: Development of a bimodal, in situ crosslinking method to achieve multifactor release from electrospun gelatin.

    Science.gov (United States)

    Kishan, Alysha; Walker, Taneidra; Sears, Nick; Wilems, Thomas; Cosgriff-Hernandez, Elizabeth

    2018-01-17

    To better mimic native tissue microenvironments, current efforts have moved beyond single growth factor delivery to more complex multiple growth factor delivery with distinct release profiles. Electrospun gelatin, a widely investigated drug delivery vehicle, requires postprocessing crosslinking techniques that generate a mesh with uniform crosslinking density, limiting the ability to deliver multiple factors at different rates. Herein, we describe a method to independently control release of multiple factors from a single electrospun gelatin mesh. Two in situ crosslinking modalities, photocrosslinking of methacyrlated gelatin and reactive crosslinking of gelatin with a diisocyanate, are coelectrospun to generate distinct fiber populations with different crosslinking chemistry and density in a single mesh. The photocrosslinked gelatin-methacrylate resulted in a relatively rapid release of a model protein (48 ± 12% at day 1, 96 ± 3% at day 10) due to diffusion of embedded protein from the crosslinked fibers. The reactive crosslinking system displayed a more sustained release (7 ± 5% at day 1, 33 ± 2% at day 10) that was attributed to the conjugation of protein to gelatin with the diisocyanate, requiring degradation of gelatin prior to diffusion out of the fibers. Both modalities displayed tunable release profiles. Subsequent release studies of a cospun mesh with two different crosslinked fiber populations confirmed that the cospun mesh displayed multifactor release with independent release profiles. Overall, this bimodal, in situ crosslinking approach enables the delivery of multiple factors with distinct release kinetics from a single mesh and is expected to have broad utility in tissue engineering. © 2018 Wiley Periodicals, Inc. J Biomed Mater Res Part A, 2018. © 2018 Wiley Periodicals, Inc.

  13. Alasdair

    Directory of Open Access Journals (Sweden)

    Heron

    2012-11-01

    Full Text Available The article aims to investigate the Calvin’s Genevan Service Order. It focuses on the question how the Psalter Calvin shaped the worship of the Reformed Church in Geneva. The article follows the critical edition of the Genevan prayer in Calvini Opera Selecta and in the German Studienausgabe as the two main published editions of the Genevan order with its related texts. The article shows that Calvin adhered to the general line of the Swiss and Upper German Reformations. It explores the understanding of worship reflected in the Genevan Service Order and the specific significance of its musical aspect. The article illustrates why Calvin gave the psalms the place he did in Genevan Reformed worship.

  14. A Biography of Distinguished Scientist Gilbert Newton Lewis (by Edward S. Lewis)

    Science.gov (United States)

    Harris, Reviewed By Harold H.

    1999-11-01

    reminded that quality counts, too. His story deserves much greater recognition (he should have won a Nobel of his own) and I am happy to see the appearance of this biography. On the other hand, it is unfortunate that a better book did not result from the author's heartfelt best intentions. Edward Lewis covers his father's career in barely over 100 pages of uninspiring prose. Ten percent of that is wasted in printing letters from famous scientists, many of them Lewis's students and Nobel laureates, endorsing the greatness of their colleague. Even the title of the book is off-putting: if the subject of a biography is "distinguished", it should not be necessary to make the claim in the title. I also wonder at the price of this slim volume. In the more than fifty years since Lewis died in 1946, nearly all of his students have also died. Even his chemist son had difficulty in finding contemporaries of his father who could provide recollections and original material for the history. The best of his sources is this Journal, which published in January-March issues of 1984 the proceedings of a symposium on the life and work of G. N. Lewis that had been held March 30-31, 1982, in Las Vegas. I recommend those papers, by Derek Davenport, Richard Lewis (G. N.'s other chemist son), John Servos, Melvin Calvin, Glenn Seaborg, Gerald Branch, Leo Brewer, Kenneth Pitzer, Jacob Bigeleisen, Anthony Stranges, Linus Pauling, William Jensen, and Michael Kasha.

  15. Cynthia J. Najdowski: Psi Chi/APA Edwin B. Newman Graduate Research Award

    Science.gov (United States)

    American Psychologist, 2012

    2012-01-01

    Presents a short biography of the winner of the American Psychological Association's Psi Chi/APA Edwin B. Newman Graduate Research Award. The 2012 winner is Cynthia J. Najdowski for an outstanding research paper that examines how jurors' judgments are influenced by a juvenile defendant's confession and status as intellectually disabled. Through…

  16. The Mathematics of Mikhael Gromov

    DEFF Research Database (Denmark)

    Hansen, Vagn Lundsgaard

    2009-01-01

    Laudatio for the Abel Prize winner Mikhael Gromov in Oslo, Norway, March 26, 2009. The lecture is recorded at htttp://media01.smartcom.no/ Microsite/webcast.aspx?eventid=4117......Laudatio for the Abel Prize winner Mikhael Gromov in Oslo, Norway, March 26, 2009. The lecture is recorded at htttp://media01.smartcom.no/ Microsite/webcast.aspx?eventid=4117...

  17. Bethany Ann Teachman: Award for Distinguished Scientific Early Career Contributions to Psychology

    Science.gov (United States)

    American Psychologist, 2012

    2012-01-01

    Presents a short biography of one of the winners of the American Psychological Association's Award for Distinguished Scientific Early Career Contributions to Psychology. The 2012 winner is Bethany Ann Teachman for transformative, translational research integrating social cognition, life-span, and perceptual approaches to investigating clinical…

  18. Performance analysis of the Malaysian elite youth squash players ...

    African Journals Online (AJOL)

    The straight and cross court drives were the most frequent strokes used by both genders, with more on the backhand side. The drop shot and straight drives contributed to most winners for the men and women respectively. Most winners were produced by the players when they occupied the middle areas of the court.

  19. Kenyan farmers discover the Internet | IDRC - International ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    2010-10-20

    Oct 20, 2010 ... With the Internet linking producers to consumers, the farmer is likely to get better value for her/his produce. "The expectation is that DrumNet ... Kenyan journalist Ken Opala is the recent Gold Medal winner of the 2003 Natali Prize — one of the world's leading awards for journalists. He is also the winner of ...

  20. U.S. Coast Guard Cutter Procurement Lessons Impacts on the Offshore Patrol Cutter Program Affordability

    Science.gov (United States)

    2015-12-01

    Guard web page (U.S. Coast Guard, 1996), The Deepwater program was initiated in response to the Deepwater Mission Analysis Report (MAR), approved...program design winners. Retrieved from http://www.informationdissemination.net/2008/02/jhsv-program- desgin - winners.html Gansler, J. S. P. (2012

  1. Market Competition and Efficient Cooperation

    NARCIS (Netherlands)

    Brandts, J.; Riedl, Arno

    2016-01-01

    We find that in market-partners, market experience has adverse effects on the efficiency of cooperation on both market-winner and market-loser pairs. In market-strangers, pairs of market-winners manage to cooperate more efficiently. These results indicate that it is not market experience per se that

  2. 76 FR 66306 - Announcement of Requirements and Registration for Leading Health Indicators App Challenge

    Science.gov (United States)

    2011-10-26

    ... place winner will receive $10,000. The second place winner will receive $3,000. And the third place... liability release will use the following language: By participating in this competition, I agree to assume... Section 508 of the Rehabilitation Act of 1973, and ones that incorporate plain language and health...

  3. Laurie R. Santos: Award for Distinguished Scientific Early Career Contributions to Psychology

    Science.gov (United States)

    American Psychologist, 2012

    2012-01-01

    Presents a short biography of one of the winners of the American Psychological Association's Award for Distinguished Scientific Early Career Contributions to Psychology. The 2012 winner is Laurie R. Santos for creative and insightful investigations of cognition across a broad range of species and psychological domains, illuminating cognitive…

  4. Bernice Lott: Award for Distinguished Senior Career Contributions to Psychology in the Public Interest

    Science.gov (United States)

    American Psychologist, 2012

    2012-01-01

    Presents a short biography of the winner of the American Psychological Association's Award for Distinguished Senior Career Contributions to Psychology in the Public Interest. The 2012 winner is Bernice Lott. Lott's commitment to the public interest has always guided her career, as her groundbreaking research on gender, ethnicity, and race…

  5. Improving carbon fixation pathways

    Energy Technology Data Exchange (ETDEWEB)

    Ducat, DC; Silver, PA

    2012-08-01

    A recent resurgence in basic and applied research on photosynthesis has been driven in part by recognition that fulfilling future food and energy requirements will necessitate improvements in crop carbon-fixation efficiencies. Photosynthesis in traditional terrestrial crops is being reexamined in light of molecular strategies employed by photosynthetic microbes to enhance the activity of the Calvin cycle. Synthetic biology is well-situated to provide original approaches for compartmentalizing and enhancing photosynthetic reactions in a species independent manner. Furthermore, the elucidation of alternative carbon-fixation routes distinct from the Calvin cycle raises possibilities that novel pathways and organisms can be utilized to fix atmospheric carbon dioxide into useful materials.

  6. Johannes Calvyn as pedagoog

    Directory of Open Access Journals (Sweden)

    S. Schoeman

    1991-01-01

    Full Text Available John Calvin as pedagogue Calvin was not only a theologian, but a competent pedagogue as well. He set a high value on education, and promoted it actively, but never systematically committed his views on it to paper. His educational views were not purely educational, but connected to a particular theological view. It is nevertheless possible to construct the broad general principles upon which his educational philosophy is based, from three sources: these are data on his educational activities in Geneva, the educational opinions that appeared in his writings, and the implications of his theological views for education.

  7. Tempus Pro Patient Monitoring System

    Science.gov (United States)

    2015-04-03

    attendees were present at the Kick-off Meeting Mr. Charlie Dean, 711th HPW/FHS Mr. Calvin Griner, AFMSA/SG51 Ms. Pam Logan, AFMSA/SG51 Maj Charles...AFMSA SG5T, (AFMESA) Mr. John Ingram, AFMSA SG5T, AFMESA Mr. John Plaga, 711 HPW/HP Human Factors Engineering Mr. Paul Bailey, AMC SG/SGR Ms. Lynn...were present at the Final Design Review Meeting Mr. Charlie Dean, 711th HPW/FHS Mr. Calvin Griner, AFMSA/SG51 8 Distribution A: Approved for

  8. Adaptive Leadership: Fighting Complexity with Complexity

    Science.gov (United States)

    2014-06-01

    the decisions made at the top of an organization are crucial to the 3 Arjen Boin, The Politics of Crisis Management : Public Leadership Under Pressure...Melvin Stodgill, Handbook of Leadership : A Survey of Theory and Research (New York, NY: Free Press; London, UK: Collier Macmillan, 1974). 4...contemporary crises that did not exist, or more accurately, could not exist in prior decades. Early organizational management theory suggested that

  9. Double-Diffusive Convection in Rotational Shear

    Science.gov (United States)

    2015-03-01

    occurred for approximately one hundred years (Schmitt 1995). An experiment by Stommel, Arons and Blanchard (1956) to determine deep ocean pressure...water density of the bottom layer dropped below density for the upper layer (Stommel, Arons and Blanchard 1956). Melvin Stern (1960) took these 1... Arons , and D. Blanchard, 1956: An oceanographical curiosity: The perpetual salt fountain. Deep Sea Res., 3, 152–153. St. Laurent, L. and R. W

  10. Joint Force Quarterly. Issue 70, 3rd Quarter, July 2013

    Science.gov (United States)

    2013-07-01

    operations (U.S. Navy/ Corbin J. Shea); MV-22B Osprey lands during operations at sea (U.S. Marine Corps/Kyle N. Runnels); and F-35 Lightening II, assigned...Presidency, and John C. Calhoun, Edwin Stanton, Elihu Root, Henry Stimson (in his first stint as Secretary of War), and Melvin Laird overseeing the...former Missile Defense Agency Director Lieu- tenant General Henry A. Obering, USAF, in James W. Canan, “Conversations with Lt. Gen. Henry A. Obering

  11. Semiclassical Strings in Supergravity PFT

    OpenAIRE

    Banerjee, Aritra; Biswas, Sagar; Panigrahi, Kamal L.

    2014-01-01

    Puff field theory (PFT) is an example of a non-local field theory which arises from a novel embedding of D-branes in a Melvin universe. We study several rotating and pulsating string solutions of the F-string equations of motion in the supergravity dual of the PFT. Further, we find a PP-wave geometry from this non-local spacetime by applying a Penrose limit and comment on its similarity with the maximally supersymmetric PP-wave background.

  12. Grief Reporting: A Print Media Content Analysis of the Gander, Newfoundland Air Disaster

    Science.gov (United States)

    1988-03-11

    Press, 1986). McQuail , Denis. Mass Communication Theory . (Beverly Hills, California: Sage Publications, 1984). Mencher, Melvin. News Reporting and...Adversaries. (Boston: Beacon Press, 1970). Rivers, William L. and Wilbur Schramm. Responsibility in Mass Communication . Rev. ed. (New -York, N.Y...NUMBERS Grief Reporting: A Print Media Content Analysis of the Gander, Newfoundland Air Disaster 6. AUTHOR( S ) Captain Barbara Ann Goodno 7. PERFORMING

  13. The Lens of Power: Aerial Reconnaissance and Diplomacy in the Airpower Century

    Science.gov (United States)

    2013-01-01

    Norfolk, Virginia.63 In April 1914, Lieutenants Patrick Bellinger and Melvin Stolz made the first aerial sortie over the port of Veracruz , Mexico...trade partner (PNTR) status based on the PRC’s indignant way of handling the crisis.1380 Other legislators proposed robust improvements in arms sales ...Secretary Powell publicly de-linked Taiwanese arms sales from the EP-3 incident very early, saying he did not want to exacerbate tensions unnecessarily

  14. The Human Operator Simulator. Volume VIII. Applications to Assessment of Operator Loading.

    Science.gov (United States)

    1977-06-14

    N62269-77-C.0109 THE HUMAN OPERATOR SIMULATOR VOLUME Vill,- APPLICATIONS TO ASSESSMENT OF OPERATOR LOADING Floyd A. Glenn Melvin I.’ Strieb Robert Jj...Kristofferson, 1967). Though compelling evidence against this theory of the "psychological moment" has been raised by experiments reported by Allport (1968) and...clearly demonstrated. 31 Is REFERENCES Allport , D.A., Phenomenal simultaneity and the perceptual moment hypo- thesis. British Journal of Psychology

  15. An Algorithm for the Vertical Structure of Aerosol Extinction in the Lowest Kilometer of the Atmosphere: Rev. 1

    Science.gov (United States)

    2017-11-01

    to be used. The statement of sky conditions can contain three pieces of information: the cloud ceiling height (or absence of a cloud ceiling), the...function of altitude. The statement of sky conditions can contain the following pieces of information: cloud ceiling height (or lack of a cloud ceiling...Structure ofAerosol Extinction in the Lowest Kilometerof the Atmosphere: Rev. 1 by Melvin G Heaps and Robert D Johnson US Army Electronics Research and

  16. Butterfly effect and holographic mutual information under external field and spatial noncommutativity

    Energy Technology Data Exchange (ETDEWEB)

    Huang, Wung-Hong; Du, Yi-Hsien [Department of Physics, National Cheng Kung University,No. 1, University Road, Tainan City 701, Taiwan (China)

    2017-02-07

    We apply the transformation of mixing azimuthal and internal coordinate or mixing time and internal coordinate to a stack of N black M-branes to find the Melvin spacetime of a stack of N black D-branes with magnetic or electric flux in string theory, after the Kaluza-Klein reduction. We slightly extend previous formulas to investigate the external magnetic and electric effects on the butterfly effect and holographic mutual information. It shows that the Melvin fields do not modify the scrambling time and will enhance the mutual information. In addition, we also T-dualize and twist a stack of N black D-branes to find a Melvin Universe supported by the flux of the NSNS b-field, which describes a non-comutative spacetime. It also shows that the spatial noncommutativity does not modify the scrambling time and will enhance the mutual information. We also study the corrected mutual information in the backreaction geometry due to the shock wave in our three model spacetimes.

  17. Author Details

    African Journals Online (AJOL)

    Gwandure, Calvin. Vol 42, No 1 (2012) - Articles Violence, Interpersonal Trust and Gullibility in HIV Risk in Africa Abstract · Vol 44, No 4 (2015) - Articles Examining Perceptions of Sexual Harassment among Recent Female Graduates in the Workplace Abstract · Vol 45, No 1 (2015) - Articles Exploring the Challenges of ...

  18. cognitio dei et nostri

    African Journals Online (AJOL)

    wird. Eine Grundfrage der Theologie und des Glaubens ist gestellt. 1.1 Der Textaufbau. Calvin setzt an den Anfang der Institutio von 1536 einen ersten Teil als. Prolegomena. Sie beginnen mit der „summa sacrae doctrinae“, die aus zwei. Teilen besteht, der cognitio dei et nostri. Es ist nun zunächst zu klären, wo der. 1. Prof.

  19. Jiří Strejc a Jan Opsimathes - apoštolové českého kalvinismu

    Czech Academy of Sciences Publication Activity Database

    Kostlán, Antonín

    -, č. 1 (2009), s. 35-55 ISSN 1804-1132 R&D Projects: GA AV ČR IAA800630802 Institutional research plan: CEZ:AV0Z80630520 Keywords : early modern Czech history * intellectual history * calvinism Subject RIV: AB - History

  20. ’Kto Bogu wiernie służy, temu wiek szczęśnie płuzy’. Czech-Polish relations in light of the album amicorum of the Moravian calvinist Jan Opsimathes

    Czech Academy of Sciences Publication Activity Database

    Kostlán, Antonín

    46-47, 22/23 (2009), s. 59-97 ISSN 0231-5955 R&D Projects: GA AV ČR IAA800630802 Institutional research plan: CEZ:AV0Z80630520 Keywords : early modern Czech history * Czech-Polish relations * calvinism Subject RIV: AB - History