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Sample records for winner mary lad

  1. Marie and Irene Curie. The first female Nobel Prize winners; Marie en IreneCurie. De eerste vrouwelijke Nobelprijswinnaars

    Energy Technology Data Exchange (ETDEWEB)

    Noordenbos, G. [Joke Smit Instituut voor Vrouwenstudies, Universiteit Leiden, Leiden (Netherlands)

    2003-07-01

    Marie Curie was awarded the Nobel Prize in 1903 and in 1911. Also her daughter, Irene Joliot-Curie, received a Nobel Prize for science in 1935. In this book an overview is given of the academic world at that time: limited access to universities for women, the carriers of both women in physics and their pioneering research and discoveries, the refusal of Marie Curie by the French Academy of Sciences, the awarding of the Nobel Prize and the assignment of Irene Joliot-Curie as the first female minister in France, the impact of the two World Wars, their married and private lives and the constant smear campaign of the press against both women. The lives and works of both women are hold against the light of the present position of women in physical sciences. [Dutch] In 1903, precies honderd jaar geleden, ontving Marie Curie als eerste vrouw de Nobelprijs voor de Wetenschap, gevolgd door een tweede Nobelprijs in 1911. Ook haar dochter Irene Joliot-Curie kreeg de Nobelprijs voor de wetenschap in 1935. Marie and Irene Curie schetst een breed beeld van de academische wereld waarin beide vrouwen zich bewogen: de beperkte toegang van vrouwen tot de universiteit, hun carrisres in de natuurkunde en baanbrekende ontdekkingen, de afwijzing van Marie door de Franse Academie des Sciences, de toekenning van de Nobelprijs en de benoeming van Irene als eerste vrouwelijke minister in Frankrijk, de invloed van de twee Wereldoorlogen, hun huwelijks- en priveleven en de niet aflatende hetze van de pers tegen beiden. In de door mannen gedomineerde wereld van de natuurwetenschappen liep de uitzonderingspositie van beide vrouwen als rode draad door hun curieuze levens. Het leven en werk van de Curies wordt geactualiseerd door deze tegen het licht te houden van de huidige positie van vrouwen in de natuurwetenschappen. Het bereiken van de top van de wetenschap door vrouwen blijkt nog steeds uitzonderlijk.

  2. Marie Curie. Marie Curie

    Energy Technology Data Exchange (ETDEWEB)

    Ksoll, P.; Voegtle, F.

    1988-01-01

    The book describes the private life and scientific career of the winner of two Nobel prizes. By presenting excerpts from her letters and photographs, the authors succeed in conveying a comprehensive picture of the personality of a woman of outstanding achievement in all areas.

  3. Marie Curie; Marie Curie

    Energy Technology Data Exchange (ETDEWEB)

    Quinn, S.

    1996-04-01

    Marie Curie was an exceptional woman. Twice crowned by the Nobel price, a first time in 1903 with her husband and Henri Becquerel for the radioactivity discovery, and the second time in 1911 for a chemistry Nobel price, for the discovery and characterization of the radium element. With the Marie Curie`s life, it is the radioactivity history which is talked here; Rutherford, Einstein, Perrin, Langevin, Bohr and some others take their place in this atomic physics novel; a well-informed biography is presented here with a solid scientific documentation, a very serious work, indeed. (N.C.).

  4. Laboratory Astrophysics Division of the AAS (LAD)

    Science.gov (United States)

    Salama, Farid; Drake, R. P.; Federman, S. R.; Haxton, W. C.; Savin, D. W.

    2012-01-01

    The purpose of the Laboratory Astrophysics Division (LAD) is to advance our understanding of the Universe through the promotion of fundamental theoretical and experimental research into the underlying processes that drive the Cosmos. LAD represents all areas of astrophysics and planetary sciences. The first new AAS Division in more than 30 years, the LAD traces its history back to the recommendation from the scientific community via the White Paper from the 2006 NASA-sponsored Laboratory Astrophysics Workshop. This recommendation was endorsed by the Astronomy and Astrophysics Advisory Committee (AAAC), which advises the National Science Foundation (NSF), the National Aeronautics and Space Administration (NASA), and the U.S. Department of Energy (DOE) on selected issues within the fields of astronomy and astrophysics that are of mutual interest and concern to the agencies. In January 2007, at the 209th AAS meeting, the AAS Council set up a Steering Committee to formulate Bylaws for a Working Group on Laboratory Astrophysics (WGLA). The AAS Council formally established the WGLA with a five-year mandate in May 2007, at the 210th AAS meeting. From 2008 through 2012, the WGLA annually sponsored Meetings in-a-Meeting at the AAS Summer Meetings. In May 2011, at the 218th AAS meeting, the AAS Council voted to convert the WGLA, at the end of its mandate, into a Division of the AAS and requested draft Bylaws from the Steering Committee. In January 2012, at the 219th AAS Meeting, the AAS Council formally approved the Bylaws and the creation of the LAD. The inaugural gathering and the first business meeting of the LAD were held at the 220th AAS meeting in Anchorage in June 2012. You can learn more about LAD by visiting its website at http://lad.aas.org/ and by subscribing to its mailing list.

  5. Laboratory Astrophysics Division of The AAS (LAD)

    Science.gov (United States)

    Salama, Farid; Drake, R. P.; Federman, S. R.; Haxton, W. C.; Savin, D. W.

    2012-10-01

    The purpose of the Laboratory Astrophysics Division (LAD) is to advance our understanding of the Universe through the promotion of fundamental theoretical and experimental research into the underlying processes that drive the Cosmos. LAD represents all areas of astrophysics and planetary sciences. The first new AAS Division in more than 30 years, the LAD traces its history back to the recommendation from the scientific community via the White Paper from the 2006 NASA-sponsored Laboratory Astrophysics Workshop. This recommendation was endorsed by the Astronomy and Astrophysics Advisory Committee (AAAC), which advises the National Science Foundation (NSF), the National Aeronautics and Space Administration (NASA), and the U.S. Department of Energy (DOE) on selected issues within the fields of astronomy and astrophysics that are of mutual interest and concern to the agencies. In January 2007, at the 209th AAS meeting, the AAS Council set up a Steering Committee to formulate Bylaws for a Working Group on Laboratory Astrophysics (WGLA). The AAS Council formally established the WGLA with a five-year mandate in May 2007, at the 210th AAS meeting. From 2008 through 2012, the WGLA annually sponsored Meetings in-a-Meeting at the AAS Summer Meetings. In May 2011, at the 218th AAS meeting, the AAS Council voted to convert the WGLA, at the end of its mandate, into a Division of the AAS and requested draft Bylaws from the Steering Committee. In January 2012, at the 219th AAS Meeting, the AAS Council formally approved the Bylaws and the creation of the LAD. The inaugural gathering and the first business meeting of the LAD were held at the 220th AAS meeting in Anchorage in June 2012. You can learn more about LAD by visiting its website at http://lad.aas.org/ and by subscribing to its mailing list.

  6. Marie Curie; Marie Curie

    Energy Technology Data Exchange (ETDEWEB)

    Lemire, L

    2001-07-01

    This book presents the biography of Marie Curie who has been the very first woman appointed professor at the Sorbonne university (Paris, France). She discovered thorium radioactivity and identified with Pierre Curie, his husband, the polonium in 1898. She isolated the radium in 1910 with A. Debierne. (J.S.)

  7. Marie Curie; Marie Curie

    Energy Technology Data Exchange (ETDEWEB)

    Trotereau, J.

    2011-07-01

    The legend has only retained from Marie Curie (1867-1934) the image of a hard and brilliant worker, pioneer in the radioactivity domain, and who awarded twice the Nobel Price. Behind the scientist, there is a women, Marya Salomea Sklodowska, the 'Polish', who was considered during some time as an 'alien', an 'atheistic intellectual', an 'emancipated women'. When she died alone in July 1934, after an exhausting life of labour, her funeral led to no official ceremony or speech. This small book summarizes the biography of the most famous female scientist in the world

  8. Photowalk contest winners

    CERN Multimedia

    Roberto Cantoni

    2010-01-01

    The local winners of the global particle physics Photowalk have been announced by the five participating laboratories. At CERN, Diego Giol and Christian Stephani were the jury’s favourites, and their photos will now go forward to the global vote, competing against the local winners from DESY in Germany, Fermilab in the US, KEK in Japan and TRIUMF in Canada. Two prizes are to be awarded, one selected by a global jury, the other by popular vote – it’s time to get voting!   Diego Giol #1 The global winners of the Photowalk contest will be revealed by the second week of October, but the local CERN winners were announced last week. After three weeks of work, two meetings of the jury and three successive selections, 20 photos were chosen from the 792 entries. The three highest-ranked will participate in the final competition. The public can vote for their favourite photos on the interactions.org website until 8 October. Only two photographers took the three winning photo...

  9. Marie Curie

    International Nuclear Information System (INIS)

    Ksoll, P.; Voegtle, F.

    1988-01-01

    The book describes the private life and scientific career of the winner of two Nobel prizes. By presenting excerpts from her letters and photographs, the authors succeed in conveying a comprehensive picture of the personality of a woman of outstanding achievement in all areas. (DG) [de

  10. Everyone is a winner

    DEFF Research Database (Denmark)

    Reuben, Ernesto; Tyran, Jean-Robert

    2010-01-01

    We test if cooperation is promoted by rank-order competition between groups in which all groups can be ranked first, i.e. when everyone can be a winner. This type of rank-order competition has the advantage that it can eliminate the negative externality a group's performance imposes on other groups....... However, it has the disadvantage that incentives to outperform others are absent, and therefore it does not eliminate equilibria where all groups cooperate at an equal but low level. We find that all-can-win competition produces a universal increase in cooperation and benefits a majority of individuals...

  11. Marie Curie

    International Nuclear Information System (INIS)

    Quinn, S.

    1996-04-01

    Marie Curie was an exceptional woman. Twice crowned by the Nobel price, a first time in 1903 with her husband and Henri Becquerel for the radioactivity discovery, and the second time in 1911 for a chemistry Nobel price, for the discovery and characterization of the radium element. With the Marie Curie's life, it is the radioactivity history which is talked here; Rutherford, Einstein, Perrin, Langevin, Bohr and some others take their place in this atomic physics novel; a well-informed biography is presented here with a solid scientific documentation, a very serious work, indeed. (N.C.)

  12. Marie Curie

    International Nuclear Information System (INIS)

    Lemire, L.

    2001-01-01

    This book presents the biography of Marie Curie who has been the very first woman appointed professor at the Sorbonne university (Paris, France). She discovered thorium radioactivity and identified with Pierre Curie, his husband, the polonium in 1898. She isolated the radium in 1910 with A. Debierne. (J.S.)

  13. [Women in natural sciences--Nobel Prize winners].

    Science.gov (United States)

    Zuskin, Eugenija; Mustajbegović, Jadranka; Lipozencić, Jasna; Kolcić, Ivana; Spoljar-Vrzina, Sanja; Polasek, Ozren

    2006-01-01

    Alfred Bernhard Nobel was the founder of the Nobel Foundation, which has been awarding world-known scientists since 1901, for their contribution to the welfare of mankind. The life and accomplishments of Alfred Bernhard Nobel are described as well as scientific achivements of 11 women, Nobel prize winners in the field of physics, chemistry, physiology and/or medicine. They are Marie Sklodowska Curie, Maria Goeppert Mayer, Irene Joliot-Curie, Dorothy Crowfoot Hodgkin, Gerty Theresa Radnitz Cori, Rosalyn Sussman Yalow, Barbara McClintock, Rita Levi-Montalcini, Gertrude Elion, Christine Nusslein-Volhard and Linda B. Buck.

  14. Marie Curie

    International Nuclear Information System (INIS)

    Trotereau, J.

    2011-01-01

    The legend has only retained from Marie Curie (1867-1934) the image of a hard and brilliant worker, pioneer in the radioactivity domain, and who awarded twice the Nobel Price. Behind the scientist, there is a women, Marya Salomea Sklodowska, the 'Polish', who was considered during some time as an 'alien', an 'atheistic intellectual', an 'emancipated women'. When she died alone in July 1934, after an exhausting life of labour, her funeral led to no official ceremony or speech. This small book summarizes the biography of the most famous female scientist in the world

  15. Right ventricular function assessment in single LAD lesion patients ...

    African Journals Online (AJOL)

    Rania Gaber

    2015-10-09

    Oct 9, 2015 ... Abstract Background: Strain and strain rate imaging is currently the most popular echocardio- graphic technique that reveals subclinical myocardial damage, and data are not available on this imaging method with regard to assessing right ventricular involvement in single LAD lesion. Aim: To evaluate right ...

  16. LADS: Optimizing Data Transfers using Layout-Aware Data Scheduling

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Youngjae [ORNL; Atchley, Scott [ORNL; Vallee, Geoffroy R [ORNL; Shipman, Galen M [ORNL

    2015-01-01

    While future terabit networks hold the promise of signifi- cantly improving big-data motion among geographically distributed data centers, significant challenges must be overcome even on today s 100 gigabit networks to real- ize end-to-end performance. Multiple bottlenecks exist along the end-to-end path from source to sink. Data stor- age infrastructure at both the source and sink and its in- terplay with the wide-area network are increasingly the bottleneck to achieving high performance. In this paper, we identify the issues that lead to congestion on the path of an end-to-end data transfer in the terabit network en- vironment, and we present a new bulk data movement framework called LADS for terabit networks. LADS ex- ploits the underlying storage layout at each endpoint to maximize throughput without negatively impacting the performance of shared storage resources for other users. LADS also uses the Common Communication Interface (CCI) in lieu of the sockets interface to use zero-copy, OS-bypass hardware when available. It can further im- prove data transfer performance under congestion on the end systems using buffering at the source using flash storage. With our evaluations, we show that LADS can avoid congested storage elements within the shared stor- age resource, improving I/O bandwidth, and data transfer rates across the high speed networks.

  17. Breast Cancer Startup Challenge winners

    Science.gov (United States)

    Ten winners of a world-wide competition to bring emerging breast cancer research technologies to market faster were announced today by the Avon Foundation for Women, in partnership with NCI and the Center for Advancing Innovation (CAI). Avon is providing

  18. "Lights on at the end of the party": are lads' mags mainstreaming dangerous sexism?

    Science.gov (United States)

    Horvath, Miranda A H; Hegarty, Peter; Tyler, Suzannah; Mansfield, Sophie

    2012-11-01

    Research has suggested that some magazines targeted at young men - lads' mags - are normalizing extreme sexist views by presenting those views in a mainstream context. Consistent with this view, young men in Study 1 (n = 90) identified more with derogatory quotes about women drawn from recent lads' mags, and from interviews with convicted rapists, when those quotes were attributed to lads' mags, than when they were attributed to convicted rapists. In Study 2, 40 young women and men could not reliably judge the source of those same quotes. While these participants sometimes voiced the belief that the content of lads' mags was 'normal' while rapists' talk was 'extreme', they categorized quotes from both sources as derogatory with equal frequency. Jointly, the two studies show an overlap in the content of convicted rapists' talk and the contents of contemporary lads' mags, and suggest that the framing of such content within lads' mags may normalize it for young men. ©2011 The British Psychological Society.

  19. The Transitional Legend of Winners

    Directory of Open Access Journals (Sweden)

    Ivan Kovačević

    2016-03-01

    Full Text Available During 2006 a number of stories that featured the motive of great gain under dramatic circumstances were repeatedly told in betting-houses in Kragujevac, a town in Serbia. The main character of these legends is an empoverished victim of transition who, thanks to luck and help of friends, wins a great sum of money betting. Besides describing the preceding transitional "fall" of the winner (getting fired, failing in private enterprise, the legends describe his economical and social prosperity initiated by capital gained through betting (starting succesfull enterprises, buying good shares. Diachronically following other "sudden wealth" legends this transitional legend speaks about the establishing of a new system of values that, in the categories of social promotion, makes up for the old principles that marked the period of socialism.

  20. And now, for the winners.

    CERN Multimedia

    Alizée Dauvergne

    2010-01-01

    The Computer Security Day held on 10 June was a success. There were eight presentations, with some forty people attending each session.     The presentation videos can be viewed on Indico. The computer security team’s new website is now up and running, with a wealth of useful information and advice. Go to http://cern.ch/Computer.Security.     The quiz attracted 130 participants, and the answers have now been posted on line! The quiz winners are: Lars Aprin, Richard Baud, Thibaut Bernard, Brice Copy, Daniele de Ruschi, Sébastien Gadrat, Amanda Garcia Munoz, Stephen Gowdy, Joni Hahkala, Joseph Izen, Ryszard Erazm Jurga, Jukka Klem, Danila Oleynik, Ian Pong, Pascal Serge Roguet, Jani Tapani Taskinen, Jan Therhaag, Yves Thurel, Adrian Vogel, Thomas White. Well done to all! If you haven’t done so already, you should soon be getting your prize (i.e. a book, a T-shirt or a bag, etc.).  

  1. Marie Sklodowska Curie

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education. Marie Sklodowska Curie. Articles written in Resonance – Journal of Science Education. Volume 6 Issue 3 March 2001 pp 94-96 Classics. Rays Emitted by Compounds of Uranium and of Thorium · Marie Sklodowska Curie · More Details Fulltext PDF ...

  2. Mary M Mader

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education. Mary M Mader. Articles written in Resonance – Journal of Science Education. Volume 2 Issue 1 January 1997 pp 53-59 General Article. Fostering Creativity in Students A Short Synthesis Project for the Organic Chemistry Laboratory · Mary M Mader Charles A ...

  3. Marie Skoldowska Curie

    Indian Academy of Sciences (India)

    editors

    Becquerel had already established that uranium rays could discharge an electroscope. Initially, Marie's assignment was to measure the power of ionization of these rays. Unlike Roentgen and Becquerel who used photographic plates and fluorescent screens to study these rays, Marie employed a different technique, which.

  4. The Song Stuck in My Head Phenomenon: A Melodic Din in the LAD?

    Science.gov (United States)

    Murphey, Tim

    1990-01-01

    Focuses on the relationship between involuntary verbal rehearsal, Piaget's egocentric speech, Vygotsky's inner speech, and the song stuck in my head phenomena. It is hypothesized that song may act as a Language Acquisition Device (LAD) activator or be a strategy of the LAD in the ontogenetic development of language. (28 references) (Author/VWL)

  5. Why do winners keep winning? Androgen mediation of winner but not loser effects in cichlid fish

    Science.gov (United States)

    Oliveira, Rui F.; Silva, Ana; Canário, Adelino V.M.

    2009-01-01

    Animal conflicts are influenced by social experience such that a previous winning experience increases the probability of winning the next agonistic interaction, whereas a previous losing experience has the opposite effect. Since androgens respond to social interactions, increasing in winners and decreasing in losers, we hypothesized that socially induced transient changes in androgen levels could be a causal mediator of winner/loser effects. To test this hypothesis, we staged fights between dyads of size-matched males of the Mozambique tilapia (Oreochromis mossambicus). After the first contest, winners were treated with the anti-androgen cyproterone acetate and losers were supplemented with 11-ketotestosterone. Two hours after the end of the first fight, two contests were staged simultaneously between the winner of the first fight and a naive male and between the loser of first fight and another naive male. The majority (88%) of control winners also won the second interaction, whereas the majority of control losers (87%) lost their second fight, thus confirming the presence of winner/loser effects in this species. As predicted, the success of anti-androgen-treated winners in the second fight decreased significantly to chance levels (44%), but the success of androgenized losers (19%) did not show a significant increase. In summary, the treatment with anti-androgen blocks the winner effect, whereas androgen administration fails to reverse the loser effect, suggesting an involvement of androgens on the winner but not on the loser effect. PMID:19324741

  6. And the winners were... Innovation Awards

    CERN Document Server

    2003-01-01

    The winners of the 2003 Economist innovation awards included Tim Berners-Lee for the WWW and Dr. Damadian for his suggestion that NMR could be used as a medical detection device for cancer (1/2 page).

  7. Everyone Is a Winner

    DEFF Research Database (Denmark)

    Reuben, Ernesto; Tyran, Jean-Robert

    In this paper, we study the effectiveness of intergroup competition in promoting cooperative behavior. We focus on intergroup competition that is non-rival in the sense that everyone can be a winner. This type of competition does not give groups an incentive to outcompete others. However, in spit...

  8. Queen Mary Two Step

    OpenAIRE

    Melin, Mats H.

    2007-01-01

    n/a Dance devised by Mats Melin in October 2007 whilst teaching Ceilidh dancing on board the cruise ship Queen Mary 2 crossing the Atlantic from Southampton to New York and back with the Ian Muir Sound from Prestwick. The segment of music featured is from Ian Muir Scottish Dance Band's recording of an Eva Three step.

  9. Fajonyomi, Mary Grace

    African Journals Online (AJOL)

    Fajonyomi, Mary Grace. Vol 10, No 2 (2002) - Articles Reorientation of the Value System of the Nigerian Adolescents through Guidance and Counselling Abstract. ISSN: 1117-1421. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's Partners ...

  10. Avangardistid Moskvas / Mari Sobolev

    Index Scriptorium Estoniae

    Sobolev, Mari, 1968-

    2000-01-01

    Valdek Alberi ja Taave Tuutma videoinstallatsioonist "Think different" näitusel "Salon 2000" Moskva Kunstnike Keskmajas 16.-26. III. Kuraator Mari Sobolev. Eesti väljapaneku vastukajast ja Jüri Arrakust, kelle maalid olid näitusel "Balti meistrid", ajalehes "Kommersant". Moskva kunstinäitustest.

  11. Marie Curie: scientific entrepreneur

    Energy Technology Data Exchange (ETDEWEB)

    Boudia, S. [Curie Muesum, Paris (France)

    1998-12-01

    Marie Curie is best known for her discovery of radium one hundred years ago this month, but she also worked closely with industry in developing methods to make and monitor radioactive material, as Soraya Boudia explains. One hundred years ago this month, on 28 December 1898, Pierre Curie, Marie Sklodowska-Curie and Gustave Bemont published a paper in Comptes-rendus - the journal of the French Academy of Sciences. In the paper they announced that they had discovered a new element with astonishing properties: radium. But for one of the authors, Marie Curie, the paper was more than just the result of outstanding work: it showed that a woman could succeed in what was then very much a male-dominated scientific world. Having arrived in Paris from Poland in 1891, Marie Curie became the first woman in France to obtain a PhD in physics, the first woman to win a Nobel prize and the first woman to teach at the Sorbonne. She also helped to found a new scientific discipline: the study of radioactivity. She became an icon and a role-model for other women to follow, someone who succeeded - despite many difficulties - in imposing herself on the world of science. Although Curie's life story is a familiar and well documented one, there is one side to her that is less well known: her interaction with industry. As well as training many nuclear physicists and radiochemists in her laboratory, she also became a scientific pioneer in industrial collaboration. In this article the author describes this side of Marie Curie. (UK)

  12. Marie Curie: scientific entrepreneur

    International Nuclear Information System (INIS)

    Boudia, S.

    1998-01-01

    Marie Curie is best known for her discovery of radium one hundred years ago this month, but she also worked closely with industry in developing methods to make and monitor radioactive material, as Soraya Boudia explains. One hundred years ago this month, on 28 December 1898, Pierre Curie, Marie Sklodowska-Curie and Gustave Bemont published a paper in Comptes-rendus - the journal of the French Academy of Sciences. In the paper they announced that they had discovered a new element with astonishing properties: radium. But for one of the authors, Marie Curie, the paper was more than just the result of outstanding work: it showed that a woman could succeed in what was then very much a male-dominated scientific world. Having arrived in Paris from Poland in 1891, Marie Curie became the first woman in France to obtain a PhD in physics, the first woman to win a Nobel prize and the first woman to teach at the Sorbonne. She also helped to found a new scientific discipline: the study of radioactivity. She became an icon and a role-model for other women to follow, someone who succeeded - despite many difficulties - in imposing herself on the world of science. Although Curie's life story is a familiar and well documented one, there is one side to her that is less well known: her interaction with industry. As well as training many nuclear physicists and radiochemists in her laboratory, she also became a scientific pioneer in industrial collaboration. In this article the author describes this side of Marie Curie. (UK)

  13. Calcium regulation of EGF-induced ERK5 activation: role of Lad1-MEKK2 interaction.

    Directory of Open Access Journals (Sweden)

    Zhong Yao

    Full Text Available The ERK5 cascade is a MAPK pathway that transmits both mitogenic and stress signals, yet its mechanism of activation is not fully understood. Using intracellular calcium modifiers, we found that ERK5 activation by EGF is inhibited both by the depletion and elevation of intracellular calcium levels. This calcium effect was found to occur upstream of MEKK2, which is the MAP3K of the ERK5 cascade. Co-immunoprecipitation revealed that EGF increases MEKK2 binding to the adaptor protein Lad1, and this interaction was reduced by the intracellular calcium modifiers, indicating that a proper calcium concentration is required for the interactions and transmission of EGF signals to ERK5. In vitro binding assays revealed that the proper calcium concentration is required for a direct binding of MEKK2 to Lad1. The binding of these proteins is not affected by c-Src-mediated phosphorylation on Lad1, but slightly affects the Tyr phosphorylation of MEKK2, suggesting that the interaction with Lad1 is necessary for full Tyr phosphorylation of MEKK2. In addition, we found that changes in calcium levels affect the EGF-induced nuclear translocation of MEKK2 and thereby its effect on the nuclear ERK5 activity. Taken together, these findings suggest that calcium is required for EGF-induced ERK5 activation, and this effect is probably mediated by securing proper interaction of MEKK2 with the upstream adaptor protein Lad1.

  14. Klassika & ekskremendid / Mari Sobolev

    Index Scriptorium Estoniae

    Sobolev, Mari, 1968-

    2002-01-01

    20.-21. aprillil toimus Pärnus 8. Fideo- ja Vilmifestival alapealkirjaga "Eksperimendid ja klassika". Peakorraldaja Rael Artel. Rami Raski filmist "Legowitz 1999" (soome rühmitus Vivid), läti filmist "Love, death & television", Concordia ülikooli ("Ülemus") ja Academia Grata (portreefilmid Asta Isakist, Andrus Joonasest jm.) programmist, Kadriann Kibuse ja Liina Paakspuu filmist "Urban Obsessions", Mirja-Mari Smidti ja Allan Tõnissoo videost, Marianne Männi koomiksitest kataloogis

  15. Rape culture, lad culture and everyday sexism: researching, conceptualizing and politicizing new mediations of gender and sexual violence

    OpenAIRE

    Phipps, Alison; Ringrose, Jessica; Renold, Emma; Jackson, Carolyn

    2017-01-01

    Introduction to Special Issue of Journal of Gender Studies entitled Rape culture, lad culture and everyday sexism: Researching, conceptualizing and politicizing new mediations of gender and sexual violence.

  16. Winners of student essay contest receive awards

    Science.gov (United States)

    1999-01-01

    At the Apollo/Saturn V Center, George Meguiar (center left) and George English (center right) present scholarships to two students who entered an essay contest in conjunction with the 30th Anniversary of Apollo 11. The winners shown are Kyla Davis Horn, of Cocoa Beach, and Kyle Rukaczewski, of Satellite Beach. A third winner, Jason Gagnon, of Viera, was unable to attend. Meguiar and English head the Apollo 11 Commemoration Association which sponsored the contest in conjunction with Florida Today newspaper. The presentation was made at the Apollo/Saturn V Center during an anniversary banquet that honored all the people who made the Apollo Program possible. Special guests included former Apollo astronauts Neil Armstrong, Edwin 'Buzz' Aldrin, Gene Cernan and Walt Cunningham, who shared their experiences with the audience.

  17. More Than a Magazine: Exploring the Links Between Lads' Mags, Rape Myth Acceptance, and Rape Proclivity.

    Science.gov (United States)

    Romero-Sánchez, Mónica; Toro-García, Virginia; Horvath, Miranda A H; Megías, Jesús L

    2015-06-03

    Exposure to some magazines aimed at young male readers-lads' mags-has recently been associated with behaviors and attitudes that are derogatory toward women, including sexual violence. In the present study, a group of Spanish adult men was exposed to the covers of a lads' mag while a second group was exposed to the covers of a neutral magazine. Results showed that, compared with participants in the second group, participants who were exposed to covers of lads' mags who also showed high rape myth acceptance and legitimized the consumption of such magazines reported higher rape proclivity in a hypothetical situation. These findings suggest the need to further explore the possible detrimental effects of some sexualized media that are widely accepted in many Western countries. © The Author(s) 2015.

  18. Identifying Winners and Losers in Transportation

    OpenAIRE

    David Levinson

    2002-01-01

    This paper explores the issues surrounding transportation equity for effects both external and internal to transportation. Several examples of transportation "improvements" imposing transportation costs on more individuals than who are benefited are provided. Beyond counting the number of winners and losers, several quantitative measures of equity are suggested. To that end, transportation benefit cost analyses should include an "Equity Impact Statement". This statement would consider the dis...

  19. CERN welcomes Intel Science Fair winners

    CERN Multimedia

    Katarina Anthony

    2012-01-01

    This June, CERN welcomed twelve gifted young scientists aged 15-18 for a week-long visit of the Laboratory. These talented students were the winners of a special award co-funded by CERN and Intel, given yearly at the Intel International Science and Engineering Fair (ISEF).   The CERN award winners at the Intel ISEF 2012 Special Awards Ceremony. © Society for Science & the Public (SSP). The CERN award was set up back in 2009 as an opportunity to bring some of the best and brightest young minds to the Laboratory. The award winners are selected from among 1,500 talented students participating in ISEF – the world's largest pre-university science competition, in which students compete for more than €3 million in awards. “CERN gave an award – which was obviously this trip – to students studying physics, maths, electrical engineering and computer science,” says Benjamin Craig Bartlett, 17, from South Carolina, USA, wh...

  20. Mary, dogma, and psychoanalysis.

    Science.gov (United States)

    Todd, E H

    1985-06-01

    Why does Mary hold her prominent place in Catholic theology to the extent that five specific dogmas have developed around her? Psychoanalytic theory suggests dogma arises out of the psychic needs of people and psychic needs of people are expressed in dogma. The early views of Erich Fromm, a disciple of Freud, are presented to demonstrate that Marian dogma arose from the psychic needs of the people. The views of both Catholic and Protestant thinkers are presented, as well as theological and psychiatric views.

  1. Whatever Happened to Mary Ellen?

    Science.gov (United States)

    Lazoritz, Stephen

    1990-01-01

    The case of Mary Ellen, whose maltreatment as a child began the organized response to child abuse in the United States, is reviewed. The paper emphasizes Mary Ellen's rescue from her stepmother, her life after intervention, and her meaningful and productive life as a wife and mother. (JDD)

  2. Winners and Losers of Danish Football

    DEFF Research Database (Denmark)

    Storm, Rasmus K.

    performance outputs in relation to key factors of this function. The approach reflected represents a sociological supplement to the ordinary performance benchmarks often used in sports economics, revealing FC København and Brøndby IF as the main winners and AGF and Akademisk Boldklub (AB) as main losers......This paper deals with European and Danish soccer and its commercialization focusing on the Danish male first tier clubs. Based on the systems theoretical argument that sport serves as a mirror system in (late-) modern society, the Danish football clubs are measured against a simple matrix of main...

  3. Robotic Software Integration Using MARIE

    Directory of Open Access Journals (Sweden)

    Carle Côté

    2006-03-01

    Full Text Available This paper presents MARIE, a middleware framework oriented towards developing and integrating new and existing software for robotic systems. By using a generic communication framework, MARIE aims to create a flexible distributed component system that allows robotics developers to share software programs and algorithms, and design prototypes rapidly based on their own integration needs. The use of MARIE is illustrated with the design of a socially interactive autonomous mobile robot platform capable of map building, localization, navigation, tasks scheduling, sound source localization, tracking and separation, speech recognition and generation, visual tracking, message reading and graphical interaction using a touch screen interface.

  4. The Longhorn Array Database (LAD): an open-source, MIAME compliant implementation of the Stanford Microarray Database (SMD).

    Science.gov (United States)

    Killion, Patrick J; Sherlock, Gavin; Iyer, Vishwanath R

    2003-08-20

    The power of microarray analysis can be realized only if data is systematically archived and linked to biological annotations as well as analysis algorithms. The Longhorn Array Database (LAD) is a MIAME compliant microarray database that operates on PostgreSQL and Linux. It is a fully open source version of the Stanford Microarray Database (SMD), one of the largest microarray databases. LAD is available at http://www.longhornarraydatabase.org Our development of LAD provides a simple, free, open, reliable and proven solution for storage and analysis of two-color microarray data.

  5. The Longhorn Array Database (LAD: An Open-Source, MIAME compliant implementation of the Stanford Microarray Database (SMD

    Directory of Open Access Journals (Sweden)

    Iyer Vishwanath R

    2003-08-01

    Full Text Available Abstract Background The power of microarray analysis can be realized only if data is systematically archived and linked to biological annotations as well as analysis algorithms. Description The Longhorn Array Database (LAD is a MIAME compliant microarray database that operates on PostgreSQL and Linux. It is a fully open source version of the Stanford Microarray Database (SMD, one of the largest microarray databases. LAD is available at http://www.longhornarraydatabase.org Conclusions Our development of LAD provides a simple, free, open, reliable and proven solution for storage and analysis of two-color microarray data.

  6. Microarray data visualization and analysis with the Longhorn Array Database (LAD).

    Science.gov (United States)

    Killion, Patrick J; Iyer, Vishwanath R

    2004-12-01

    The wide availability and use of DNA microarrays has brought the power of whole-genome functional characterization to a large variety of research environments. Microarrays, however, also introduce significant infrastructural and analytical concerns with respect to the long-term warehousing, annotation, and visualization of immense data sets. The Longhorn Array Database (LAD) is a MIAME-compliant microarray database that operates on PostgreSQL and Linux. It is a free and completely open-source software solution, and provides a systematic and proven environment in which vast experiment sets can be safely archived, securely accessed, biologically annotated, quantitatively analyzed, and visually explored. This unit provides the complete set of information needed to successfully deploy, configure, and use LAD for the purposes of two-color DNA microarray analysis and visualization.

  7. Research on verification and validation strategy of detonation fluid dynamics code of LAD2D

    Science.gov (United States)

    Wang, R. L.; Liang, X.; Liu, X. Z.

    2017-07-01

    The verification and validation (V&V) is an important approach in the software quality assurance of code in complex engineering application. Reasonable and efficient V&V strategy can achieve twice the result with half the effort. This article introduces the software-Lagrangian adaptive hydrodynamics code in 2D space (LAD2D), which is self-developed software in detonation CFD with plastic-elastic structure. The V&V strategy of this detonation CFD code is presented based on the foundation of V&V methodology for scientific software. The basic framework of the module verification and the function validation is proposed, composing the detonation fluid dynamics model V&V strategy of LAD2D.

  8. Lad os lære af nutidens private ledere - ikke fortidens

    DEFF Research Database (Denmark)

    Torfing, Jacob

    2017-01-01

    Hvis vi endelig skal lære af den private sektor en gang til, så lad os dog lære af de bedste i klassen i stedet for at kigge i bakspejlet og genopfinde ledelsestænkning fra 60’erne og 70’erne, skriver professor Jacob Torfing.......Hvis vi endelig skal lære af den private sektor en gang til, så lad os dog lære af de bedste i klassen i stedet for at kigge i bakspejlet og genopfinde ledelsestænkning fra 60’erne og 70’erne, skriver professor Jacob Torfing....

  9. Google Science Fair winner visits CERN

    CERN Multimedia

    Katarina Anthony

    2012-01-01

    Google Science Fair Grand Prize winner Brittany Michelle Wenger today wrapped up a day-and-a-half's visit of the CERN site. Her winning project uses an artificial neural network to diagnose breast cancer – a non-invasive technique with significant potential for use in hospitals.   Brittany Michelle Wenger at CERN's SM18 Hall. Besides winning a $50,000 scholarship from Google and work experience opportunities with some of the contest hosts, Brittany was offered a personal tour of CERN. “This visit has just been incredible,” she says. “I got to speak with [CERN's Director for Accelerators and Technology] Steve Myers about some of the medical applications and technologies coming out of the LHC experiments and how they can be used to treat cancer. We talked about proton therapy and hadron therapy, which could really change the way patients are treated, improving success rates and making treatment not such an excruciating process. That ...

  10. 2016 Federal Green Challenge Award Winners in the Southeast Region

    Science.gov (United States)

    2016 FGC award winners in the Southeast are: the Department of Human Services’ U.S. Citizenship and Immigration Services Southeast Regional Office and Department of Energy’s East Tennessee Technology Park.

  11. Winners and losers of IWRM in Tanzania

    Directory of Open Access Journals (Sweden)

    Barbara van Koppen,

    2016-10-01

    Full Text Available This paper focuses on the application of the concept of Integrated Water Resources Management (IWRM in Tanzania. It asks: how did IWRM affect the rural and fast-growing majority of smallholder farmersʼ access to water which contributes directly to poverty alleviation and employment creation in a country where poverty and joblessness are high? Around 1990, there were both a strong government-led infrastructure development agenda and IWRM ingredients in place, including cost-recovery of state services aligning with the Structural Adjustment Programmes, water management according to basin boundaries and the dormant colonial water rights (permits system. After the 1990s, the World Bank and other donors promoted IWRM with a strong focus on hydroelectric power development, River Basin Water Boards, transformation of the water right system into a taxation tool, and assessment of environmental flows. These practices became formalised in the National Water Policy (2002 and in the Water Resources Management Act (2009. Activities in the name of IWRM came to be closely associated with the post-2008 surge in large-scale land and water deals. Analysing 25 years of IWRM, the paper identifies the processes and identities of the losers (smallholders and – at least partially – the government and the winners (large-scale water users, including recent investors. We conclude that, overall, IWRM harmed smallholdersʼ access to water and rendered them more vulnerable to poverty and unemployment.

  12. Marie Curie: Physicist and Woman

    Science.gov (United States)

    Howes, Ruth

    Marie Sklodowska was born in Warsaw on November 7, 1867. Girls were not allowed to attend college in Poland, so Marie found a well-paying post as a governess in rural village which she held for three years while helping her older sister complete medical school in Paris. Then Marie moved to Paris and graduated first in her class at the Sorbonne with a master's degree in physics in 1893. In 1895, she married the talented young physicist, Pierre Curie. Marie decided to investigate the radioactive components of the mineral pitchblende for her dissertation. The work involved chemical analysis of a ton of material in an unheated shed. Pierre joined her and at the end of 1898, the Curies announced the discovery of radium and polonium. Through 1899, Marie labored to measure the atomic weight of radium. In 1903, Marie earned her doctorate, the first for a woman in France, and the Curies split the Nobel Prize in Physics with Henri Becquerel. They became widely known, besieged by the press and frequently invited to make presentations and be awarded honors. They hated fame and both suffered bad health. In April, 1906, Pierre Curie was struck by a wagon and killed instantly. Marie was left as a single mother with two young daughters. Fortunately, the Sorbonne hired her to fill Pierre's position. In 1911, she was rejected for membership in the French Academy of Science because she was a woman. Also in 1911, she was accused of having an affair with a married French physicist Paul Langevin. The resulting scandal hit the press and brought angry mobs to her home. In the middle of this hullaballoo, she was informed that she had won a second Nobel Prize, this time in Chemistry. When World War I broke out, Marie mounted x-ray units on cars and became a heroine. She visited the United States in 1921 where President Harding presented her with a gram of radium. She continued her scientific studies in spite of declining health until her death in 1934. Professor Emerita.

  13. Logical Analysis of Data (LAD model for the early diagnosis of acute ischemic stroke

    Directory of Open Access Journals (Sweden)

    Hoehn Gerard

    2008-07-01

    Full Text Available Abstract Background Strokes are a leading cause of morbidity and the first cause of adult disability in the United States. Currently, no biomarkers are being used clinically to diagnose acute ischemic stroke. A diagnostic test using a blood sample from a patient would potentially be beneficial in treating the disease. Results A classification approach is described for differentiating between proteomic samples of stroke patients and controls, and a second novel predictive model is developed for predicting the severity of stroke as measured by the National Institutes of Health Stroke Scale (NIHSS. The models were constructed by applying the Logical Analysis of Data (LAD methodology to the mass peak profiles of 48 stroke patients and 32 controls. The classification model was shown to have an accuracy of 75% when tested on an independent validation set of 35 stroke patients and 25 controls, while the predictive model exhibited superior performance when compared to alternative algorithms. In spite of their high accuracy, both models are extremely simple and were developed using a common set consisting of only 3 peaks. Conclusion We have successfully identified 3 biomarkers that can detect ischemic stroke with an accuracy of 75%. The performance of the classification model on the validation set and on cross-validation does not deteriorate significantly when compared to that on the training set, indicating the robustness of the model. As in the case of the LAD classification model, the results of the predictive model validate the function constructed on our support-set for approximating the severity scores of stroke patients. The correlation and root mean absolute error of the LAD predictive model are consistently superior to those of the other algorithms used (Support vector machines, C4.5 decision trees, Logistic regression and Multilayer perceptron.

  14. Mary Shelley: Teaching and Learning through "Frankenstein"

    Science.gov (United States)

    Girard, Theresa M.

    2009-01-01

    In the writing of "Frankenstein", Mary Shelley was able to change the course of women's learning, forever. Her life started from an elite standpoint as the child of Mary Wollstonecraft and William Godwin. As such, she was destined to grow to be a major influence in the world. Mary Shelley's formative years were spent with her father and his many…

  15. Louis Leakey and Mary Leakey

    Indian Academy of Sciences (India)

    Permanent link: https://www.ias.ac.in/article/fulltext/reso/020/08/0667-0679. Keywords. Palaeoanthropology; human evolution; Louis Leakey; Mary Leakey; Africa; Olduvai gorge; fossil hominids. Author Affiliations. Rajan Gaur1. Department of Anthropology, Panjab University, Sector 14, Chandigarh UT 160 014, India ...

  16. Charcot-Marie-Tooth Disease

    Science.gov (United States)

    Charcot-Marie-Tooth disease (CMT) is a group of genetic nerve disorders. It is named after the three doctors who first identified it. ... a nerve biopsy. There is no cure. The disease can be so mild you don't realize ...

  17. Mary Slessor Journal of Medicine

    African Journals Online (AJOL)

    The Mary Slessor Journal of Medicine (MJSM) publishes original research papers, review articles, case reports and short communications on any aspect of health and tropical diseases. All papers are refereed by independent assessors. Vol 9, No 1 (2009). DOWNLOAD FULL TEXT Open Access DOWNLOAD FULL TEXT ...

  18. CERNland/Prince of Asturias competition winners tour CERN

    CERN Multimedia

    Katarina Anthony

    2014-01-01

    Last week, the Laboratory rolled out the red carpet for the six young winners of the CERNland/Prince of Asturias competition. From a visit of the CMS detector to dessert with the Director-General, these young talents were given the full VIP treatment. Nothing less would do for our winners!   The competition's youngest winners study the CMS detector. For the CERNland/Prince of Asturias competition winners, Easter 2014 would be unforgettable. Besides visits to all the main CERN landmarks, they attended an award ceremony in the Main Building in their honour. Among the audience were CERN Director-General, Rolf Heuer, the Permanent Representative of Spain to the United Nations Office at Geneva, Ana Maria Menendez Perez, and the Director of the Prince of Asturias Foundation, Teresa Sanjurjo González. The ceremony was also an opportunity for the CERN community to interact with the young winners. “They brought with them such heartfelt enthusiasm,” says CERN&am...

  19. Charcot-Marie-Tooth disease.

    LENUS (Irish Health Repository)

    Reilly, Mary M

    2011-03-01

    Charcot-Marie-Tooth (CMT) disease is the commonest inherited neuromuscular disorder affecting at least 1 in 2,500. Over the last two decades, there have been rapid advances in understanding the molecular basis for many forms of CMT with more than 30 causative genes now described. This has made obtaining an accurate genetic diagnosis possible but at times challenging for clinicians. This review aims to provide a simple, pragmatic approach to diagnosing CMT from a clinician\\'s perspective.

  20. The Role of Lad Magazines in Priming Men's Chronic and Temporary Appearance-Related Schemata: An Investigation of Longitudinal and Experimental Findings

    Science.gov (United States)

    Aubrey, Jennifer Stevens; Taylor, Laramie D.

    2009-01-01

    We present a program of research investigating the effects of lad magazines on male body self-consciousness and appearance anxiety. Study 1, based on panel data from undergraduate men, showed that lad magazine exposure in Year 1 predicted body self-consciousness in Year 2. Study 2 was an experiment that showed that men assigned to view objectified…

  1. Winners & Sinners: What's Hot and What's Not in Alumni Merchandising.

    Science.gov (United States)

    Larson, Wendy Ann

    1990-01-01

    A large part of any merchandising program is picking products that will sell. Sixty alumni professionals were asked about their ideas. Some of the winners included a watch with the institution's seal, a windsock, and athletic shoes. Some of the losers included a sweater and a commemorative plate. (MLW)

  2. Hybrid All-Pay and Winner-Pay Contests

    DEFF Research Database (Denmark)

    Lagerlöf, Johan

    2017-01-01

    In many contests in economic and political life, both all-pay and winner-pay expenditures matter for winning. This paper studies such hybrid contests under symmetry and asymmetry. The symmetric model is very general but still yields a simple closed-form solution. More contestants tend to lead to ...

  3. Steven MacCall: Winner of LJ's 2010 Teaching Award

    Science.gov (United States)

    Berry, John N., III

    2010-01-01

    This article profiles Steven L. MacCall, winner of "Library Journal's" 2010 Teaching Award. An associate professor at the School of Library and Information Studies (SLIS) at the University of Alabama, Tuscaloosa, MacCall was nominated by Kathie Popadin, known as "Kpop" to the members of her cohort in the online MLIS program at SLIS. Sixteen of…

  4. 40 CFR 105.15 - How are award winners recognized?

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 21 2010-07-01 2010-07-01 false How are award winners recognized? 105.15 Section 105.15 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) WATER... ceremony as recognition for an outstanding technological achievement or an innovative process, method or...

  5. Winners of the 2017 IDRC Doctoral Research Awards | IDRC ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    2017-11-30

    Nov 30, 2017 ... Michelle Savard, a 2016 awardee, hands out a certificate for the completion of an entrepreneurial training program that she arranged for war-affected single mothers in Uganda. IDRC is pleased to announce the winners of the 2017 IDRC Doctoral Research Awards. Awardees will conduct field research in ...

  6. Näitused / Mari Sobolev

    Index Scriptorium Estoniae

    Sobolev, Mari, 1968-

    1998-01-01

    Rotermanni soolaladu. "Elektrokardiogramm" (tegevuskunsti üritus); Vaal-galerii. Antoni T̉pies "Litograafiaid aastatest 1973-1995"; Mari Kadanik, Eero Barndõk, Rain Ader "Pildid" (maalid); Paldiski Põhikool. "Niemenlautta ja Hugo Simbergi fotod" (soome kunstniku fotode koopiad, pildistatud enne 1915. a.; Kullo lastegalerii. Neli uut näitust.(lastekunst); Arhitektuurimuuseum. Arnold Matteus - Tartu linna arhitekt (juubelinäitus), Alvar Aalto "Kolm objekti Eestis"; Linnagalerii Tallinnas. "Valge" (ruumi- ja moekunsti näitus); Sammas-galerii. Jüri Jegorow "Insect" (arvutigraafika); Endla Teatri palmisaal. "Muzik in der Kunst" (Tallinna kunstitudengite näitus); Eesti Rahvusraamatukogu. Õie Kütt "Uued ja vanad ehted"

  7. On Mary Wollstonecraft's Protofeminist Thought

    OpenAIRE

    Brajković, Lidija

    2015-01-01

    Mary Wollstonecraft is an 18th century author whose name and ideas still echo in feminist world. She advocated a change in approach to education for women which would lead to their better position in society and would end an oppression to which they were exposed. Wollstonecraft's life was turbulent and gave her plenty of material to observe and discuss the position of women, starting from her own family and later love affairs. Also, she felt the atmosphere of some great social events such as ...

  8. Marie Underile pühendatakse konverents

    Index Scriptorium Estoniae

    2008-01-01

    Tartus Eesti Kirjandusmuuseumis toimuvast Marie Underi 125. sünniaastapäevale pühendatud konverentsist ja näitusest "Kunsti Marie Underi kodust". Vt. ka Keel ja Kirjandus, nr. 4, 2008, lk. 317; Looming, nr. 4, 2008, lk. 635; Keel ja Kirjandus, nr. 7, lk. 570-572

  9. Mary Anne Chambers | IDRC - International Development Research ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    A former Member of Provincial Parliament, Mary Anne served as Minister of Training, Colleges and Universities, and Minister of Children and Youth Services in the Government of Ontario. She is also a former senior vice-president of Scotiabank. A graduate of the University of Toronto, Mary Anne has received honorary ...

  10. Mary Seacole: global nurse extraordinaire.

    Science.gov (United States)

    Staring-Derks, Corry; Staring, Jeroen; Anionwu, Elizabeth N

    2015-03-01

    A discussion of recently discovered literature that reveals how after the Crimean War ended in 1856, Jamaican nurse, doctress and entrepreneur Mary Seacole travelled more widely and gained further international recognition than had previously been appreciated. New findings demonstrate that Seacole's international charitable and business activities were reported more widely than realised. Recently discovered literature uncovers her networking and strategic skills in various social milieus. A former Scutari nurse and 39 other women, offered their service to Seacole to nurse British soldiers in India. Newspapers also reported the medal she had been awarded from the Turkish government. Discussion paper. Digitized 19th-century newspaper reports, and 1857 Dutch and 1858 French translations of Seacole's autobiography and a recently discovered handwritten letter dated 1 October 1857 from Seacole to Sir Henry Storks, at the time Secretary for Military Correspondence at the War Office, London. Awareness of the findings affords a more thorough understanding of the scope and diversity of nursing history. This can provide valuable role models for the 21st century generations of competent and self-confident healthcare professionals. The new evidence offers further testimony that Seacole can truly be considered as one such figurehead. British and international primary sources reveal Mary Seacole as an historical and charismatic global phenomenon, more than had been previously realised. © 2014 John Wiley & Sons Ltd.

  11. Recovery of distal coronary flow reserve in LAD and LCx after Y-Graft intervention assessed by transthoracic echocardiography

    Science.gov (United States)

    2010-01-01

    Background Y- graft (Y-G) is a graft formed by the Left Internal Mammary Artery (LIMA) connected to the Left Anterior Descending Artery (LAD) and by a free Right Internal Mammary Artery (RIMA) connected to LIMA and to a Marginal artery of Left Circumflex Artery (LCx). Aim of the work was to study the flow of this graft during a six months follow-up to assess whether the graft was able to meet the request of all the left coronary circulation, and to assess whether it could be done by evaluation of coronary flow reserve (CFR). Methods In 13 consecutive patients submitted to Y-G (13 men), CFR was measured in distal LAD and in distal LCx from 1 week after , every two months, up to six months after operation (a total of 8 tests for each patient) by means of transthoracic echocardiography (TTE) and Adenosine infusion (140 mcg/kg/min for 3-6 min). A Sequoia 256, Acuson-Siemens, was used. Contrast was used when necessary (Levovist 300 mg/ml solution at a rate of 0,5-1 ml/min). Max coronary flow diastolic velocity post-/pre-test ≥2 was considered normal CFR. Results Coronary arteriography revealed patency of both branches of Y-G after six months. Accuracy of TTE was 100% for LAD and 85% for LCx. Feasibility was 100% for LAD and 85% for LCx. CFR improved from baseline in LAD (2.21 ± 0.5 to 2.6 ± 0.5, p = 0.03) and in LCx (1.7 ± 1 to 2.12 ± 1, p = 0.05). CFR was under normal at baseline in 30% of patients vs 8% after six months in LAD (p = 0.027), and in 69% of patients vs 30% after six months in LCx (p = 0.066). Conclusion CFR in Y-G is sometimes reduced in both left territories postoperatively but it improves at six months follow-up. A follow-up can be done non-invasively by TTE and CFR evaluation. PMID:20716357

  12. Plastic evolution behavior of H340LAD-Z steel by an optical method

    International Nuclear Information System (INIS)

    Guo, Nan; Liang, Jin; Yu, Qiang; Qian, Boxing

    2017-01-01

    An optical method based on digital image correlation (DIC) technology was proposed to measure the plastic evolution of the high-strength low alloy steel H340LAD-Z. The basic principle of DIC technology is introduced, and then, the use of a 3D deformation measurement system and electronic universal testing machine to dynamically measure plastic evolution during the tensile yield stage is described. Through the full-field full-process measurement of plastic deformation during the yield stage in the 0°, 45° and 90° loading directions, the plastic evolution law was revealed. The results demonstrate that the proposed 3D DIC method can accurately reveal the starting and ending times for plastic evolution. The specimens in the three directions exhibit different plastic evolution behaviors, although they have similar yield strengths and yield times. The specimens in the 45° and 90° loading directions began to enter plastic deformation from bottom to top and the plastic area was maintained in a constant deformed state, while the evolution behavior in the 0° direction transited from both sides to the middle and plastic deformation was uneven. It is important to study plastic evolution of a metal sheet to determine the material properties and to provide an accurate basis for finite element modeling.

  13. Simultaneous denitrification and phosphorus removal by Agrobacterium sp. LAD9 under varying oxygen concentration.

    Science.gov (United States)

    Ma, Tao; Chen, Qian; Gui, Mengyao; Li, Can; Ni, Jinren

    2016-04-01

    Although efficient aerobic denitrification has received increasing attention, few studies have been made on simultaneous denitrification and phosphorus removal (SDPR) under aerobic condition. In this study, SDPR by an efficient aerobic denitrifier, Agrobacterium sp. LAD9, was firstly demonstrated. High nitrate and phosphorus removal rates of 7.50 and 1.02 mg L(-1) h(-1) were achieved in wide range of O2 concentration from 5.92 to 20.02 mg L(-1). The N2O production would be inhibited as O2 concentration exceeded 11.06 mg L(-1), while the phosphorus removal efficiency would be generally improved with increasing O2 concentration. (15)N mass spectrometry revealed that nitrogen removal accorded with the typical aerobic denitrification pathway, while (31)P nuclear magnetic resonance spectroscopy ((31)P NMR) indicated the fate of phosphorus to cells, extracellular polymeric substances (EPS), and polyphosphate (poly-P) of the denitrifier. EPS acted as a reservoir of phosphorus and the transformation of poly-P was dynamic and depended on initial orthophosphate (ortho-P) content. The aerobic SDPR would greatly simplify the conventional wastewater treatment processes which required separated considerations of nitrogen and phosphorus removal.

  14. Alert with destruction of stratospheric ozone: 95 Nobel Prize Winners

    International Nuclear Information System (INIS)

    Santamaria, J.; Zurita, E.

    1995-01-01

    After briefly summarizing the discoveries of the 95 Nobel Prize Winners in Chemistry related to the threats to the ozone layer by chemical pollutants, we make a soft presentation of the overall problem of stratospheric ozone, starting with the destructive catalytic cycles of the pollutant-based free radicals, following with the diffusion mathematical models in Atmospheric Chemistry, and ending with the increasing annual drama of the ozone hole in the Antarctica. (Author)

  15. Spring Research Festival and NICBR Collaboration Winners Announced | Poster

    Science.gov (United States)

    By Carolynne Keenan, Contributing Writer, and Ashley DeVine, Staff Writer The winners of the 2014 Spring Research Festival (SRF), held May 7 and 8, were recognized on July 2, and included 20 NCI at Frederick researchers: Matthew Anderson, Victor Ayala, Matt Bess, Cristina Bergamaschi, Charlotte Choi, Rami Doueiri, Laura Guasch Pamies, Diana Haines, Saadia Iftikhar, Maria Kaltcheva, Wojciech Kasprzak, Balamurugan Kuppusamy, James Lautenberger, George Lountos, Megan Mounts, Uma Mudunuri, Martha Sklavos, Gloriana Shelton, Alex Sorum, and Shea Wright.

  16. Louisiana SIP: LAC 33:III Ch 2132. Stage II Vapor Recovery Systems for Control of Vehicle Refuelling Emissions at Gasoline Dispensing Facilities; SIP effective 2011-08-04 (LAd34) and 2016-02-29 (LAd47) to 2017-09-27

    Science.gov (United States)

    Louisiana SIP: LAC 33:III Ch 2132. Stage II Vapor Recovery Systems for Control of Vehicle Refuelling Emissions at Gasoline Dispensing Facilities; SIP effective 2011-08-04 (LAd34) and 2016-02-29 (LAd47) to 2017-09-27

  17. Marie Curie during ORT6

    Science.gov (United States)

    2003-01-01

    Marie Curie sits on the lander petal prior to deployment during the pre launch Operations Readiness Test (ORT) 6.Pathfinder, a low-cost Discovery mission, is the first of a new fleet of spacecraft that are planned to explore Mars over thenext ten years. Mars Global Surveyor, already en route, arrives at Mars on September 11 to begin a two year orbital reconnaissance of the planet's composition, topography, and climate. Additional orbiters and landers will follow every 26 months.The Jet Propulsion Laboratory, Pasadena, CA, developed and manages the Mars Pathfinder mission for NASA's Office of Space Science, Washington, D.C. JPL is an operating division of the California Institute of Technology (Caltech). The Imager for Mars Pathfinder (IMP) was developed by the University of Arizona Lunar and Planetary Laboratory under contract to JPL. Peter Smith is the Principal Investigator.

  18. Marie Curie during ORT4

    Science.gov (United States)

    2003-01-01

    Marie Curie rover drives down the rear ramp during Operational Readiness Test (ORT) 4.Pathfinder, a low-cost Discovery mission, is the first of a new fleet of spacecraft that are planned to explore Mars over thenext ten years. Mars Global Surveyor, already en route, arrives at Mars on September 11 to begin a two year orbital reconnaissance of the planet's composition, topography, and climate. Additional orbiters and landers will follow every 26 months.The Jet Propulsion Laboratory, Pasadena, CA, developed and manages the Mars Pathfinder mission for NASA's Office of Space Science, Washington, D.C. JPL is an operating division of the California Institute of Technology (Caltech). The Imager for Mars Pathfinder (IMP) was developed by the University of Arizona Lunar and Planetary Laboratory under contract to JPL. Peter Smith is the Principal Investigator.

  19. Jean-Marie Dufour 1937-2007

    CERN Multimedia

    2007-01-01

    Jean-Marie Dufour, who was head of the CERN Legal Service from 1974 until his retirement in 2001, passed away on 8 July. Following his arrival at CERN in 1966 during the crucial phase of expansion of the Laboratory’s site, Jean-Marie Dufour ensured that CERN’s rules were applied while taking part in essential stages of the Organization’s development. With his fine mind and erudition, Jean-Marie Dufour, a staunch European devoted to the CERN cause, has left his mark on the Legal Service. The Service will publish a tribute to him in a forthcoming issue of the Bulletin.

  20. Radium, Marie Curie and modern science.

    Science.gov (United States)

    Langevin-Joliot, H

    1998-11-01

    In 1898, the discovery of two new elements, polonium and radium, reawakened interest in the topic of uranic rays discovered 2 years before by H. Becquerel. Radioactivity, a name coined by Marie Curie, became a major research field for decades. The contrasting personalities of Pierre Curie, already a first-rank physicist, and of the young Marie Curie-Sklodowska as they undertook their common work are described. It is shown how a well-chosen quantitative method and a systematic approach combining physics and chemistry led to the discovery within less than 1 year. The special role of radium and the determination of its atomic weight by Marie Curie followed by her long-term program for accumulating pure radium salts are emphasized. The first woman with a full professorship at a French University, Marie Curie created and managed the Radium Institute.

  1. Mary Loli Martínez-Aldama

    Indian Academy of Sciences (India)

    2016-01-27

    Aldama. Articles written in Journal of Astrophysics and Astronomy. Volume 36 Issue 4 December 2015 pp 457-465 Review. Observations of the Ca I I IR Triplet in High Luminosity Quasars: Exploring the Sample · Mary Loli ...

  2. Radikaalsus muuseumi kaitsva teki all / Mari Sobolev

    Index Scriptorium Estoniae

    Sobolev, Mari, 1968-

    2004-01-01

    Rotermanni soolalaos avatud Marco (Marko) Laimre isiknäituse "Küsimused ja vastused" puhul 13. IV toimunud konverentsist. Johannes Saare, Eha Komissarovi, Hanno Soansi, Anders Härmi ja Mari Sobolevi ettekannetest

  3. Google Science Fair 2012 : Grand Prize Winner Brittany Wenger

    CERN Multimedia

    Maximilien Brice

    2012-01-01

    17-18 age category AND Grand Prize Winner: Brittany Wenger (USA)—“Global Neural Network Cloud Service for Breast Cancer.” Brittany’s project harnesses the power of the cloud to help doctors accurately diagnose breast cancer. Brittany built an application that compares individual test results to an extensive dataset stored in the cloud, allowing doctors to assess tumors using a minimally-invasive procedure. Brittany Michelle Wenger, and her mother, passed through the CERN Control Centre accompanied by Mike Lamont, CERN Beams Department, Operation Group Leader.

  4. "Mary Hartman, Mary Hartman"; A New Genre of Prosocial Programming, or Just Another Soap Opera?

    Science.gov (United States)

    Surlin, Stuart H.; Maloof, Mary C.

    This paper discusses the wide appeal, and the effect on the viewing audience, of traditional television soap operas. It reports on a comparison of role interactions, topics discussed by the characters, and types of topics and problems presented on the television program "Mary Hartman, Mary Hartman" with those presented on two traditional…

  5. "Mary Hartman, Mary Hartman": An Analysis of Satire as a Violation of Soap Opera Stereotypes.

    Science.gov (United States)

    Gaulard, Joan M.

    The soap opera "Mary Hartman, Mary Hartman" presents an interesting new genre in television, as it defies the conventional standards and stereotypes associated with daytime drama. The central character is not a dependent victim but a survivor who indicates to her viewers the concept which advertisers and media management have of them. A…

  6. The extent of myocardium at Risk for LAD, RCA and LCx using contrast enhanced SSFP and T2-weighted imaging

    DEFF Research Database (Denmark)

    Nordlund, D.; Heiberg, E.; Carlsson, Marcus

    2015-01-01

    (12 excluded due to missing data, 53 due to inability to detect MaR) were included. Late gadolinium enhancement (LGE) imaging was used to assess infarct size. Imaging was performed on systems from three different vendors (Siemens, Philips, GE) and data was analyzed by a core laboratory. Culprit vessel...... was determined using angiography. Results: Average size of MaR was greater for LAD (CE-SSFP: 44+/-10%, T2w: 44+/-9% of the left ventricle [LV], p-value LV) and RCA (CE-SSFP: 31+/-7%, T2w: 30+/-8% of the LV). A comparison of coronary perfusion...

  7. The Google Science Fair winner comes to CERN

    CERN Multimedia

    CERN Bulletin

    2011-01-01

    Shree Bose, the Google Science Fair Grand Prize winner, will come to CERN for a three-day internship. She is looking forward to it and hopes to sit in the CERN Control Room, and to learn more about ALICE and in general the work going on here right now.   Google Science Fair winners Lauren Hodge (left) Shree Bose (middle) and Naomi Shah (right). (Image Copyright Google) Despite her young age, Shree Bose is already an experienced researcher. Indeed, she has already been awarded prestigious prizes in various science fairs and competitions. Aged 17, she found a way to improve ovarian cancer treatment for patients when they have built up a resistance to certain chemotherapy drugs. The project won the Grand Prize at the Google Science Fair, and together with an amazing 10-day trip to the Galapagos Islands with National Geographic Expeditions, she also won a trip to CERN. “Shree will visit several experimental sites here and will sit next to our physicists and engineers, in the CCC an...

  8. Nobel prize-winner Heinrich Rohrer visits CERN

    CERN Multimedia

    2008-01-01

    The Nobel prize-winner Heinrich Rohrer met young scientists on a recent visit to the Laboratory. From left to right: Xavier Gréhant (CERN Openlab), Ewa Stanecka (ATLAS), Magda Kowalska (ISOLDE), Heinrich Rohrer, Stéphanie Beauceron (CMS) and Ana Gago Da Silva (UNOSAT).Heinrich Rohrer, who shared the 1986 Nobel prize for physics with Gerd Binnig for the design of the scanning tunnelling microscope, visited CERN on 25 June. Welcomed by the Director-General, Robert Aymar, he visited the ATLAS cavern and control room, the Computer Centre, the Unosat project, the Antimatter Decelerator and ISOLDE. At the end of his visit, he voiced his admiration for CERN and its personnel. As a renowned Nobel prize-winner Heinrich Rohrer has the opportunity to pass on his experience and enthusiasm to young scientists. During the evening meal, at which he met five young physicists and computer scientists, who were delighted with the chance to talk to him, he stressed the importance for re...

  9. Wins, winning and winners: the commercial advertising of lottery gambling.

    Science.gov (United States)

    McMullan, John L; Miller, Delthia

    2009-09-01

    This study analyzed a sample of 920 lottery ads that were placed or played in Atlantic Canada from January 2005 to December 2006. A content analysis, involving quantitative and qualitative techniques, was conducted to examine the design features, exposure profiles and focal messages of these ads and to explore the connections between lottery advertising and consumer culture. We found that there was an "ethos of winning" in these commercials that provided the embedded words, signs, myths, and symbols surrounding lottery gambling and conveyed a powerful imagery of plentitude and certitude in a world of potential loss where there was little reference to the actual odds of winning. The tangible and emotional qualities in the ads were especially inviting to young people creating a positive orientation to wins, winning and winners, and lottery products that, in turn, reinforced this form of gambling as part of youthful consumption practices. We concluded that enticing people with the prospects of huge jackpots, attractive consumer goods and easy wins, showcasing top prize winners, and providing dubious depictions that winning is life-changing was narrow and misleading and exploited some of the factors associated with at-risk gambling.

  10. CHARCOT-MARIE-TOOTH DISEASE

    Directory of Open Access Journals (Sweden)

    Lea Leonardis

    2003-09-01

    Full Text Available Background. Charcot-Marie-Tooth (CMT disease is a common inherited disorder of the peripheral nervous system. In our paper, different types of CMT are described with their typical clinical pictures, electrophysiological signs and molecular genetic studies. CMT is classified as demyelinative and axonal type and distal motor neuronopathy.Conclusions. CMT can be of autosomal dominant, recessive and X-linked inheritance. The most frequent form of CMT is the result of the dominantly inherited duplication of chromosome 17p11.2 and is marked as CMT1A. The same group involves also rare patients with point mutation in the peripheral myelin protein-22 gene. CMT1B is associated with point mutations in protein zero gene. CMT1C is linked to chromosome 16p13.1–12.3. Patients with point mutations in early growth response 2 gene (EGR2 are included in group CMT1D. The disease can be also inhereted X-linked (CMTX with the mutations in connexin-32 gene. In autosomal recessive inherited demyelinating polyneuropathies (CMT4, mutations are found in the myotubularin-related protein-2 (CMT4B, N-myc downstream-regulated gene 1 (CMT4D, EGR2 (CMT4E, and in the periaksin (CMT4F genes. In axonal inherited neuropathy, mutations are found in KIF1beta (CMT2A and in light neurofilament (CMT2E genes, other forms map to different chromosomal loci (CMT2B, CMT2D, CMT2F. Some suggestions for the diagnostic procedures of patients with CMT are given.

  11. Marie and Pierre Curie. Life in extremes

    International Nuclear Information System (INIS)

    Roethlein, Brigitte

    2008-01-01

    In Paris in 1894, two young physicists fall in love: Marie Sklodowska and Pierre Curie. They get married and make great contributions to science, research radioactivity and discover new chemical elements. The marriage of Marie and Pierre Curie is quite modern: They work together as equals, share their thoughts and pursue their plans together as partners. They share an absolute interest in science, a love of nature, and a sceptic attitude towards the sophisticated society of the Belle Epoque. They are together 24 hours a day with hardly ever any disagreement. Whenever one of them is ill - which is quite often because of the high level of radioactivity in their laboratory -, the other will nurse him or her. After only twelve years of mutual love, Pierre Curie dies. Marie raises their two daughters on her own and continues her research. In 1911, she will be the first scientist that ever gets a second Nobel Prize. (orig.) [de

  12. Engineering international relations / Maris Riekstins ; interv. Talis Saule Archdeacon

    Index Scriptorium Estoniae

    Riekstins, Maris

    2008-01-01

    Läti annab peatselt Läänemeremaade Nõukogu eesistuja teatepulga üle Taanile. Läti välisminister Maris Riekstins Läänemeremaade Nõukogu teemadest ning suhetest Venemaaga. Maris Riekstins'i CV

  13. Remembering Mary Tyler Moore | MedlinPlus Magazine

    Science.gov (United States)

    ... Remembering Mary Tyler Moore Follow us NIH MedlinePlus Magazine Remembers Mary Tyler Moore A little more than ... helped launch the first issue of NIH MedlinePlus magazine on Capitol Hill. The award-winning actress and ...

  14. MaRIE Undulator & XFEL Systems

    Energy Technology Data Exchange (ETDEWEB)

    Nguyen, Dinh Cong [Los Alamos National Laboratory; Marksteiner, Quinn R. [Los Alamos National Laboratory; Anisimov, Petr Mikhaylovich [Los Alamos National Laboratory; Buechler, Cynthia Eileen [Los Alamos National Laboratory

    2015-03-23

    The 22 slides in this presentation treat the subject under the following headings: MaRIE XFEL Performance Parameters, Input Electron Beam Parameters, Undulator Design, Genesis Simulations, Risks, and Summary It is concluded that time-dependent Genesis simulations show the MaRIE XFEL can deliver the number of photons within the required bandwidth, provided a number of assumptions are met; the highest risks are associated with the electron beam driving the XFEL undulator; and risks associated with the undulator and/or distributed seeding technique may be evaluated or retired by performing early validation experiments.

  15. Characterizing and modelling persistence in the number of lottery winners

    Science.gov (United States)

    Antonio, Fernando J.; Mendes, Renio S.; Itami, Andreia S.; Picoli, Sergio

    2015-06-01

    Lottery is the most famous branch among all the games of chance. By analysing data from Mega-Sena, the major lottery in Brazil, we investigated the presence of persistent behaviour in the time series of the number of winners. We found that the demand for tickets grew collectively as an exponential driven by the size of the accumulated jackpot. Finally, we identified that a stochastic model grounded on the rolling-over feature of lotteries can generate correlations qualitatively similar to those observed empirically. The model is consistent with the idea that the growth in the number of bets, motivated by the size of the expected jackpot, is a mechanism generator of correlations in an apparently random scenario.

  16. CERN visit for a Norwegian Prize-winner

    CERN Multimedia

    2002-01-01

    One of the prize-winners of the Contest «Life in the Universe», the final of which was held at CERN during the Science and Technology Week in November 2001 (See Bulletin n°47/2002), came to CERN to receive his prize last June. The 15-year old Norwegian Ivar Marthinusen won a two-day visit to the Laboratory. He poses on the picture surrounded by his CERN's guardian angels: from left to right, Frank Tecker and Georges-Henry Hemelsoet from PS, Tommy Eriksson from AD, Sandrine Sanchez from the Visits Service, Ivar Mathinusen with his parents, Egil Lillestol (CERN/EP), Jens Vigen from the Library, Régine Chareyron from the Visits Service, Richard Jacobsson (CERN/EP) and Sophie Baillard from the Visits Service.

  17. Maris Jesse üks 34st maailma tervise-otsustajast / Maris Jesse

    Index Scriptorium Estoniae

    Jesse, Maris, 1968-

    2009-01-01

    21. mail Eesti esindajana Maailma Terviseorganisatsiooni täitevkogu liikmeks kinnitatud Maris Jesse vastab küsimustele, mis puudutavad tema tööd uuel ametikohal, valitsuskriisi Eestis, suhtumist proua Evelin Ilvese meditsiiniteemalistesse seisukohtadesse

  18. Women in History--Mary Seacole

    Science.gov (United States)

    Harmer, Bonnie

    2005-01-01

    Born in Jamaica in 1805, Mary Seacole (nee Grant), was the daughter of a Black Creole boarding house owner and a Scottish Army officer. Like many Creole doctress women, Seacole was taught African herbal medicine arts from her mother. In addition to understanding traditional herbal medicine, she gleaned an understanding of Western medicine from the…

  19. Mary Wollstonecraft and Catharine Macaulay on Education

    Science.gov (United States)

    Frazer, Elizabeth

    2011-01-01

    Catharine Macaulay and Mary Wollstonecraft are linked by intellectual and political bonds; for both, education is a philosophical and political preoccupation in its own right, and also interacts with philosophical questions of morality, social power, theology, truth and human action. Macaulay's philosophical and political engagements with Hobbes,…

  20. Visions of Mary Wollstonecraft: Implications for Education.

    Science.gov (United States)

    Manus, Alice L.

    This paper discusses the educational and social philosophy of Mary Wollstonecraft, an English writer of the 18th century. Her works included "Vindication of the Rights of Man," and her best know work, "Vindication of the Rights of Woman" which was published in 1792 and consisted of the first sustained argument for female…

  1. Navodnenija v umah zactroishtshikov / Maris Kuuda

    Index Scriptorium Estoniae

    Kuuda, Maris

    2007-01-01

    Kohalikel omavalitsustel pole piisavalt hoobasid sundida arendajaid üleujutusohuga arvestama. Pärnusse hotelli September rajajad (arhitektid Emil Urbel, Andrus Mark) arvestavad ujutusohuga. Arvamust avaldavad Rene Reisner, Mari Sepp, Ülo Sults, Karri Tiigisoon, Indrek Rannik, Mark Soosaar, Tiiu Pärn, Merle Looring, Rita Sepp, Kaspar Alles

  2. Ervin Pütsepa auhind Mari Laanemetsale

    Index Scriptorium Estoniae

    2011-01-01

    Ervin Pütsepa kunstiteaduse aastapreemia monograafia "Lääne modernismi ja nõukogude avangardi vahel. Mitteametlik kunst Eestis 1969-1978" eest. Saksakeelne monograafia põhineb Mari Laanemetsa Humboldti ülikoolis 2008. a. kaitstud doktoritööl

  3. Mary Elizabeth Hickox Mandels, 90, bioenergy leader

    Directory of Open Access Journals (Sweden)

    Eveleigh Douglas E

    2009-09-01

    Full Text Available Abstract Mary E H Mandels, who spearheaded the US Army's national bioconversion studies for four decades and was an early proponent of conversion of waste biomass to readily bioconvertible sugars for the production of chemicals and transportation fuels such as ethanol, died 17 February 2008 at Natick, MA, USA. She was 90.

  4. Classroom Instruction: The Influences of Marie Clay

    Science.gov (United States)

    McNaughton, Stuart

    2014-01-01

    Marie Clay's body of work has influenced classroom instruction in direct and indirect ways, through large overarching themes in our pedagogical content knowledge as well as specific smart practices. This paper focuses on her the contributions to our thinking about instruction which come from two broad theoretical concepts; emergent literacy…

  5. Bon appetite! / Mari-Liis Rebane

    Index Scriptorium Estoniae

    Rebane, Mari-Liis

    2009-01-01

    Pimedate Ööde 13. filmifestivali alafestivali Animated Dreams täispikki animafilme: Austraalia "Mary ja Max" (režissöör Elliot, Adam), Rootsi-Taani-Norra "Metropia" (režissöör Tarik Saleh), Iisraeli-Austraalia "9,99 dollarit" (režissöör Tatia Rosenthal)

  6. Mari Trentinjan : Muzhtshina jejo smerti / Bernard Lavillier

    Index Scriptorium Estoniae

    Lavillier, Bernard

    2003-01-01

    Prantsuse näitlejanna Marie Trintignant'iga (41) suri 1. augustil Prantsusmaal oma elukaaslase, ansambli "Noir Desire" liidri Bertrand Cantat' poolt Vilniuses talle tekitatud trauma tagajärjel. Näitlejanna eludraama. Järgneb 5. jaan. 2004, lk. 16-18 : ill

  7. Marie Sklodowska Curie (1867-1934)

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 6; Issue 3. Marie Sklodowska Curie (1867-1934). Featured Scientist Volume 6 Issue 3 March 2001 pp 98-98. Fulltext. Click here to view fulltext PDF. Permanent link: http://www.ias.ac.in/article/fulltext/reso/006/03/0098-0098. Resonance – Journal of ...

  8. Early Onset Charcot-Marie-Tooth Disease

    Directory of Open Access Journals (Sweden)

    J Gordon Millichap

    2005-06-01

    Full Text Available The clinical signs and genetic analysis of early-onset Charcot-Marie-Tooth disease (CMT in a 2-year-old boy and members of his family are reported from the Academic Medical Center, Amsterdam, and Sophia Children’s Hospital, Rotterdam, the Netherlands.

  9. Growth variation and heritability in a second-generation Eucalyptus urophylla progeny test at Lad Krating Plantation, Chachoengsao province, Thailand

    Directory of Open Access Journals (Sweden)

    Lucky Nhlanhla Dlamini

    2017-06-01

    Full Text Available In Thailand, Eucalyptus urophylla was introduced with the main purpose of supplying raw material for pulp and chip wood production. The demand for genetically improved seed is increasing to support high productivity plantation establishment. One of the tree improvement activities established to meet the high demand for improved seed was a second generation progeny test at Lad Krating Plantation, Thailand to provide the best material for the successful plantation program. The aim of the current study was to compare growth variation of the first and second generation of Eucalyptus urophylla progeny that could provide information on suitable families for improved quality seed. The progeny test comprised the best 45 half-sib families selected from 80 half-sib families of the first-generation progeny test. The design of the progeny test was a randomized and complete block design (16 trees/plot × 45 plots/block × 9 blocks, with 4 rows of 4 trees at a spacing of 2 m × 1 m. Growth was assessed at age 3 yr. The average height and diameter at breast height over bark (DBH, was 13.72 m, and 8.75 cm, respectively. There were highly significant (p < 0.01 differences among provenances and families in both height and DBH. The individual heritability values for height and DBH were 0.48 and 0.60, respectively. The family heritability values for height and DBH were 0.98 and 0.99, respectively. These 45 half-sib families proved to be genetically superior ensuring higher productivity and contributing to the success of the Forest Industry Organization plantation at Lad Krating.

  10. Winner-take-all in a phase oscillator system with adaptation.

    Science.gov (United States)

    Burylko, Oleksandr; Kazanovich, Yakov; Borisyuk, Roman

    2018-01-11

    We consider a system of generalized phase oscillators with a central element and radial connections. In contrast to conventional phase oscillators of the Kuramoto type, the dynamic variables in our system include not only the phase of each oscillator but also the natural frequency of the central oscillator, and the connection strengths from the peripheral oscillators to the central oscillator. With appropriate parameter values the system demonstrates winner-take-all behavior in terms of the competition between peripheral oscillators for the synchronization with the central oscillator. Conditions for the winner-take-all regime are derived for stationary and non-stationary types of system dynamics. Bifurcation analysis of the transition from stationary to non-stationary winner-take-all dynamics is presented. A new bifurcation type called a Saddle Node on Invariant Torus (SNIT) bifurcation was observed and is described in detail. Computer simulations of the system allow an optimal choice of parameters for winner-take-all implementation.

  11. Mast cell lines HMC-1 and LAD2 in comparison with mature human skin mast cells--drastically reduced levels of tryptase and chymase in mast cell lines.

    Science.gov (United States)

    Guhl, Sven; Babina, Magda; Neou, Angelos; Zuberbier, Torsten; Artuc, Metin

    2010-09-01

    To circumvent the costly isolation procedure associated with tissue mast cells (MC), two human MC lines, i.e. HMC-1 and LAD2, are frequently employed, but their relation to mature MC is unknown. Here, we quantitatively assessed their expression of MC markers in direct comparison to skin MC (sMC). sMC expressed all lineage markers at highest and HMC-1 cells at lowest levels. LAD2 cells expressed comparable high-affinity IgE receptor alpha (FcepsilonRIalpha) and FcepsilonRIgamma but less FcepsilonRIbeta than sMC and displayed slightly reduced, but robust FcepsilonRI-mediated histamine release. Only minor differences were found for total histamine content and c-Kit expression. Huge, and to this level unexpected, differences were found for MC tryptase and chymase, with sMC > LAD2 > HMC-1. Taken together, HMC-1 cells represent very immature malignantly transformed MC, whereas LAD2 cells can be considered intermediately differentiated. Because of the minute levels of MC proteases, MC lines can serve as surrogates of tissue MC to a limited degree only.

  12. Neuronal Networks with NMDARs and Lateral Inhibition Implement Winner-Takes-All

    Directory of Open Access Journals (Sweden)

    Patrick A Shoemaker

    2015-02-01

    Full Text Available A neural circuit that relies on the electrical properties of NMDA synaptic receptors is shown by numerical and theoretical analysis to be capable of realizing the winner-takes-all function, a powerful computational primitive that is often attributed to biological nervous systems. This biophysically-plausible model employs global lateral inhibition in a simple feedback arrangement. As its inputs increase, high-gain and then bi- or multi-stable equilibrium states may be assumed in which there is significant depolarization of a single neuron and hyperpolarization or very weak depolarization of other neurons in the network. The state of the winning neuron conveys analog information about its input. The winner-takes-all characteristic depends on the nonmonotonic current-voltage relation of NMDA receptor ion channels, as well as neural thresholding, and the gain and nature of the inhibitory feedback. Dynamical regimes vary with input strength. Fixed points may become unstable as the network enters a winner-takes-all regime, which can lead to entrained oscillations. Under some conditions, oscillatory behavior can be interpreted as winner-takes-all in nature. Stable winner-takes-all behavior is typically recovered as inputs increase further, but with still larger inputs, the winner-takes-all characteristic is ultimately lost. Network stability may be enhanced by biologically plausible mechanisms.

  13. Unsupervised Feature Learning With Winner-Takes-All Based STDP

    Directory of Open Access Journals (Sweden)

    Paul Ferré

    2018-04-01

    Full Text Available We present a novel strategy for unsupervised feature learning in image applications inspired by the Spike-Timing-Dependent-Plasticity (STDP biological learning rule. We show equivalence between rank order coding Leaky-Integrate-and-Fire neurons and ReLU artificial neurons when applied to non-temporal data. We apply this to images using rank-order coding, which allows us to perform a full network simulation with a single feed-forward pass using GPU hardware. Next we introduce a binary STDP learning rule compatible with training on batches of images. Two mechanisms to stabilize the training are also presented : a Winner-Takes-All (WTA framework which selects the most relevant patches to learn from along the spatial dimensions, and a simple feature-wise normalization as homeostatic process. This learning process allows us to train multi-layer architectures of convolutional sparse features. We apply our method to extract features from the MNIST, ETH80, CIFAR-10, and STL-10 datasets and show that these features are relevant for classification. We finally compare these results with several other state of the art unsupervised learning methods.

  14. Route de Meyrin-CERN: and the winner is...

    CERN Multimedia

    2012-01-01

    Last night, CERN’s engagement with society took an important step forward with the unveiling of the winner of the architectural competition for the Route de Meyrin between CERN’s entrances A and B. The winning entry is a project entitled “Metaphoros”, entered by Studio Bürgi of Ticino.   Metaphoros was selected by a jury, of which I was a member, from an impressive range of proposals from around the world. It will be some time before construction gets underway, but anyone who’d like a forward look at how the gateway to CERN will look from 2014 can visit an exhibition in the Globe opening today and running until 28 January. The exhibition focuses on the winning entry, but also has a place for the runners-up, and for the Cosmic Rings of CERN proposal for buildings and landscaping around the Globe, which, subject to external funding, will merge seamlessly with Metaphoros as the next phase in the redevelopment of CERN’s public sp...

  15. Mary Somerville and the world of science

    CERN Document Server

    Chapman, Allan

    2015-01-01

    Mary Somerville (1780-1872), after whom Somerville College Oxford was named, was the first woman scientist to win an international reputation entirely in her own right, rather than through association with a scientific brother or father. She was active in astronomy, one of the most demanding areas of science of the day, and flourished in the unique British tradition of Grand Amateurs, who paid their own way and were not affiliated with any academic institution. Mary Somerville was to science what Jane Austen was to literature and Frances Trollope to travel writing. Allan Chapman’s vivid account brings to light the story of an exceptional woman, whose achievements in a field dominated by men deserve to be very widely known.

  16. Neutrophil to lymphocyte ratio is associated with proximal/middle segment of the LAD lesions in patients with ST segment elevation infarction

    Directory of Open Access Journals (Sweden)

    Ozlem Arican Ozluk

    2017-01-01

    Full Text Available Introduction: Neutrophil to lymphocyte ratio (NLR was revaled to have a close relation with atherosclerotic cardiovascular disease. The relationship between NLR and culprit plaque localization has never been studied. Aim of the study : To evaluate the association between NLR and unstable plaque localization of left anterior descending artery (LAD in anterior miyocardial infarction patients. Material and methods : Patients admitted to our hospital with acute anterior STEMI were included. Fifhy-eight patients who have single-vessel disease at LAD and their hematological parameters were analyzed retrospectively. Proximal segment of LAD lesions were groupped as Group I and mid segment of the LAD lesion groupped as Group II. The groups were compared according to their NLR and other parameters. Results : Between group I (n = 41, mean age 52.5 ±12.7 and group II (n = 17, mean ages 52.0 ±10.8; NLR, were significantly higher in group I compared to the group II (6.9 ±5.6 vs. 3.3 ±2.0, p = 0.01. In group I, left ventricular ejection fraction (LVEF was significantly lower (p = 0.02. In correlation analyzes, NLR was positively correlated with CK MB (r = 0.32, p = 0.01 and negatively correlated with LVEF (r = –0.28, p = 0.03. Conclusions : The present study demonstrated that anterior myocardial infarction patients with high NLR had a greater possibility having proximal culprit lesion on the LAD. Therefore NLR can be used as a useful tool to culprit plaque localization in patients with acute miyocardial infarction patients.

  17. The light and brilliancy of Marie Curie

    International Nuclear Information System (INIS)

    The paper describes the life and work of Marie Curie, from her childhood to her death (at nearly 67 years), and including her marriage to Pierre Curie. The scientific work, by the Curies, leading to the discovery of polonium and radium is described, as well as the making of radium chloride. The importance of the Curies' work to theoretical science is briefly discussed, and the effects of radioactivity on the Curies is touched upon. (U.K.)

  18. Women who Worked with Marie Curie.

    Science.gov (United States)

    Pigeard-Micault, Natalie

    2015-06-01

    Marie Curie directed a research laboratory for 28 years. Between 1906 and 1934, forty five women worked under her guidance. Some were, and are, well-known in their own countries as their first woman full professor such as Ellen Gleditsch or Margaret von Wrangel, but for twenty eight of them, who were often French, nothing has ever been written. The strong presence of women in Marie Curie's laboratory has often been highlighted and has been considered as an exception, and the result of deliberate choice. Of course, these women did not choose this workplace by accident. They knew its director was a woman, a laureate of one, and after 1911, two Nobel Prizes, who was leading a well-equipped laboratory with an important radioactive source. But how did Marie Curie selected her collaborators among the many applications she received? Was her choice influenced by gender? A prosopographical research based on genealogical researches and new sources explains this presence contextually and sheds light on several questions : where did these women come from, what were their social and geographic origins, did they occupy any specific cultural or technical area inside Curie's lab, what future did they have after the laboratory? Through their lives, we can question the existence, or not, of a one profile of the female researcher in scientific areas in France.

  19. Jean-Marie Dufour 1937-2007

    CERN Multimedia

    2007-01-01

    Picture taken by Rudiger Voss in the Legal Service LibraryJean-Marie Dufour, CERN Legal Advisor from 1974 until his retirement in 2001, passed away on 8 July. For us, his colleagues in the Legal Service, Jean-Marie was a tutor and a reference, who passed on to us his passion for the practice of law in an intergovernmental organisation. As a boss, his abiding managerial quality was his unstinting loyalty to his collaborators. Jean-Marie joined CERN in 1966 and for the next 35 years was to be the guardian of the Laboratory’s rules. This was his view of the Organization: "...I have discovered [at CERN] a fascinating universe driven by two forces: science and Europe; a world of physicists and engineers who, encouraged by the States of Europe, run a remarkable Laboratory, where Europeans have achieved reconciliation and restored the grand tradition of European physics, attracting physicists from around the world; a Laboratory that transcends not only the fro...

  20. Marie and Pierre Curie. Life in extremes; Marie and Pierre Curie. Leben in Extremen

    Energy Technology Data Exchange (ETDEWEB)

    Roethlein, Brigitte

    2008-07-01

    In Paris in 1894, two young physicists fall in love: Marie Sklodowska and Pierre Curie. They get married and make great contributions to science, research radioactivity and discover new chemical elements. The marriage of Marie and Pierre Curie is quite modern: They work together as equals, share their thoughts and pursue their plans together as partners. They share an absolute interest in science, a love of nature, and a sceptic attitude towards the sophisticated society of the Belle Epoque. They are together 24 hours a day with hardly ever any disagreement. Whenever one of them is ill - which is quite often because of the high level of radioactivity in their laboratory -, the other will nurse him or her. After only twelve years of mutual love, Pierre Curie dies. Marie raises their two daughters on her own and continues her research. In 1911, she will be the first scientist that ever gets a second Nobel Prize. (orig.) [German] Im Paris des Jahres 1894 verlieben sich zwei junge Physiker: Marie Sklodowska und Pierre Curie. Sie heiraten und leisten gemeinsam Grosses fuer die Wissenschaft, erforschen die Radioaktivitaet und entdecken neue chemische Elemente. Zusammen erhalten sie den Nobelpreis. Marie und Pierre Curie fuehren eine Ehe, die ihrer Zeit weit voraus ist: Sie arbeiten gleichberechtigt miteinander, teilen ihre Gedanken und verfolgen ihre Plaene gemeinsam. Beiden eigen ist die absolute wissenschaftliche Neugier, die Liebe zur Natur und die Skepsis gegenueber der mondaenen Gesellschaft der Belle Epoque. Fast jeden Tag sind sie rund um die Uhr zusammen, dabei gibt es selten Spannungen. Wenn einer von beiden gesundheitliche Probleme hat - und das haben sie wegen der radioaktiven Belastung im Labor oft - ist der andere fuer ihn da und pflegt ihn. Nach nur zwoelf gemeinsamen Jahren der Liebe und Arbeit stirbt Pierre Curie. Marie zieht ihre beiden Toechter alleine gross und fuehrt die Forschungen weiter. 1911 erhaelt sie als erster Mensch zum zweiten Mal den

  1. Farewell Jean-Marie Good Luck Eva Welcome back Franz

    CERN Multimedia

    2001-01-01

    At the farewell reception offered by the Director-General, Professor Luciano Maiani, on the occasion of Jean-Marie Dufour's retirement from CERN, three generations of CERN Legal Counsel met. From right to left: Jean-Marie Dufour, who retires on 30 November 2001, after 35 years of service. Eva-Maria Gröniger-Voss, who takes over from Jean-Marie Dufour on 1st December 2001. Ambassador Franz Schmid, CERN Legal Counsel from 1971 to 1974.

  2. Salivary hormones and anxiety in winners and losers of an international judo competition.

    Science.gov (United States)

    Papacosta, Elena; Nassis, George P; Gleeson, Michael

    2016-01-01

    The purpose of this study was to investigate the responses of salivary hormones and salivary secretory immunoglobulin A (SIgA) and anxiety in winners and losers during an international judo competition. Twenty-three trained, male, national-level judo athletes provided three saliva samples during a competition day: morning, in anticipation of competition after an overnight fast, mid-competition, and post-competition within 15 min post-fight for determination of salivary cortisol, salivary testosterone, salivary testosterone/cortisol ratio, SIgA absolute concentrations, SIgA secretion rate and saliva flow rate. The competitive state anxiety inventory questionnaire was completed by the athletes (n = 12) after the first saliva collection for determination of somatic anxiety, cognitive anxiety and self-confidence. Winners were considered 1-3 ranking place (n = 12) and losers (n = 11) below third place in each weight category. Winners presented higher anticipatory salivary cortisol concentrations (p = 0.03) and a lower mid-competition salivary testosterone/cortisol ratio (p = 0.003) compared with losers with no differences for salivary testosterone. Winners tended to have higher SIgA secretion rates (p = 0.07) and higher saliva flow rates (p = 0.009) at mid-competition. Higher levels of cognitive anxiety (p = 0.02) were observed in the winners, without differences according to the outcome in somatic anxiety and self-confidence. The results suggest that winners experienced higher levels of physiological arousal and better psychological preparedness in the morning, and as the competition progressed, the winners were able to control their stress response better.

  3. Simulated ocean acidification reveals winners and losers in coastal phytoplankton

    Science.gov (United States)

    Alvarez-Fernandez, Santiago; Hornick, Thomas; Stuhr, Annegret; Riebesell, Ulf

    2017-01-01

    The oceans absorb ~25% of the annual anthropogenic CO2 emissions. This causes a shift in the marine carbonate chemistry termed ocean acidification (OA). OA is expected to influence metabolic processes in phytoplankton species but it is unclear how the combination of individual physiological changes alters the structure of entire phytoplankton communities. To investigate this, we deployed ten pelagic mesocosms (volume ~50 m3) for 113 days at the west coast of Sweden and simulated OA (pCO2 = 760 μatm) in five of them while the other five served as controls (380 μatm). We found: (1) Bulk chlorophyll a concentration and 10 out of 16 investigated phytoplankton groups were significantly and mostly positively affected by elevated CO2 concentrations. However, CO2 effects on abundance or biomass were generally subtle and present only during certain succession stages. (2) Some of the CO2-affected phytoplankton groups seemed to respond directly to altered carbonate chemistry (e.g. diatoms) while others (e.g. Synechococcus) were more likely to be indirectly affected through CO2 sensitive competitors or grazers. (3) Picoeukaryotic phytoplankton (0.2–2 μm) showed the clearest and relatively strong positive CO2 responses during several succession stages. We attribute this not only to a CO2 fertilization of their photosynthetic apparatus but also to an increased nutrient competitiveness under acidified (i.e. low pH) conditions. The stimulating influence of high CO2/low pH on picoeukaryote abundance observed in this experiment is strikingly consistent with results from previous studies, suggesting that picoeukaryotes are among the winners in a future ocean. PMID:29190760

  4. Interview with 2018 Hooke medal winner Andrew McAinsh.

    Science.gov (United States)

    2018-03-14

    Andrew McAinsh received his PhD from the University of Cambridge, UK, working in the laboratory of Steve Jackson on DNA damage and repair mechanisms in yeast. He then joined the laboratory of Peter Sorger as a Jane Coffin Childs Fellow to work as a post-doc on kinetochore biology at the Massachusetts Institute of Technology, Boston, USA. In 2005, he returned to the UK to establish his independent laboratory at the Marie Curie Research Institute, Surrey, before moving to the University of Warwick in 2009 to co-found the Centre for Mechanochemical Cell Biology (CMCB). Subsequently, Andrew was appointed Professor of Cell Biology and became a Wellcome Senior Investigator, and was awarded a Royal Society Wolfson Research Merit Award. He co-directs the MRC Doctoral Training Partnership in Interdisciplinary Biomedical Research, and in 2017 became Head of Division of Biomedical Sciences at Warwick Medical School. Andrew is interested in understanding how the chromosomal multi-protein complex, the kinetochore, ensures error-free chromosome segregation. He is the recipient of the 2018 Hooke medal, established to recognize an emerging leader in cell biology. The Hooke medal is awarded at the annual spring meeting of the British Society for Cell Biology (BSCB). © 2018. Published by The Company of Biologists Ltd.

  5. Mari Martin - vahelüli looja ja kandja vahel / Mari Martin ; intervjueerinud Tanel Veenre

    Index Scriptorium Estoniae

    Martin, Mari, 1983-

    2009-01-01

    Kalamari Promotioni tegevjuht, Tartu Ülikoolis majandust õppiv Mari Martin oma esimestest sammudest moemaailmas, kaubamärkide ReUse RePublic (premeeriti noorte äriideede võistlusel "Ajujaht 2009" 175000 krooniga) ja Tallinn Dolls loomisest, eesti disaineritest, unistustest seoses eesti disainiga

  6. Strange bedfellows: Cervantes and Mary Wollstonecraft Shelley

    Directory of Open Access Journals (Sweden)

    Alfredo Moro

    2017-11-01

    Full Text Available Miguel de Cervantes and Mary Shelley do seem, at first sight, two strange bedfellows. Notwithstanding the evident differences between the narrative of both authors, the English novelist showed a notable interest for the life and works of Miguel de Cervantes throughout her literary career. This article intends to offer a precise portrait of the Cervantean interests of the author of Frankenstein, tracing these through her personal correspondence, her narrative production, and finally, through her contribution to the realm of Cervantean studies: Shelley’s Life of Cervantes (1837, published in Dyonisius Lardner’s Cabinet Cyclopaedia.

  7. Maris polarization in neutron-rich nuclei

    Science.gov (United States)

    Shubhchintak; Bertulani, C. A.; Aumann, T.

    2018-03-01

    We present a theoretical study of the Maris polarization effect and its application in quasi-free reactions to assess information on the structure of exotic nuclei. In particular, we explore the dependence of the polarization effect on neutron excess and neutron-skin thickness. We discuss the uncertainties in the calculations of triple differential cross sections and of analyzing powers due the choices of various nucleon-nucleon interactions and optical potentials and the limitations of the method. Our study implies that polarization variables in (p, 2p) reactions in inverse kinematics can be an effective probe of single-particle structure of nuclei in radioactive-beam facilities.

  8. Marie Curie's contribution to Medical Physics.

    Science.gov (United States)

    Jean-Claude, Rosenwald; Nüsslin, Fridtjof

    2013-09-01

    On occasion of its 50th anniversary, the International Organization for Medical Physics (IOMP) from now on is going to celebrate annually an International Day of Medical Physics for which the 7th November, the birthday of Marie Sklodowska Curie, a most exceptional character in science at all and a pioneer of medical physics, has been chosen. This article briefly outlines her outstanding personality, sketches her fundamental discovery of radioactivity and emphasizes the impact of her various achievements on the development of medical physics at large. © 2013 Published by Elsevier Ltd on behalf of Associazione Italiana di Fisica Medica.

  9. Gifts from Mary Ainsworth and John Bowlby.

    Science.gov (United States)

    Crittenden, Patricia M

    2017-07-01

    Attachment theory has developed over many decades - and continues to develop. Its roots lie in several seminal publications of John Bowlby (the basis of attachment theory) and Mary D. S. Ainsworth (the notion of individual differences in attachment). This paper identifies the prescient contributions of these early publications and two processes (a long-term dialogue and reflection on discrepancy) that underlay emergent theory. Because I was a student of Ainsworth when both attachment theory and individual differences in attachment organization were becoming better known, I offer some of my recollections of that period, suggesting how that period may have affected current work in attachment.

  10. The life and legacy of Marie Curie.

    OpenAIRE

    Rockwell, Sara

    2003-01-01

    Marie Curie was a remarkable woman whose discoveries broke new ground in physics and chemistry and also opened the door for advances in engineering, biology, and medicine. She broke new ground for women in science: she was, for example, the first woman to receive a doctor of science degree in France, the first woman to win Nobel Prize, the first woman to lecture at the Sorbonne, the first person to win two Nobel Prizes, and the first Nobel Laureate whose child also won a Nobel Prize. Her life...

  11. In honour of Marie Sklodowska-Curie

    International Nuclear Information System (INIS)

    Karlik, Berta

    1967-01-01

    This year marks the hundredth anniversary of the birth in Poland of Marie Sklodowska-Curie, originator of the word 'radioactivity', whose early research in the subject has had far-reaching consequences for the nuclear sciences. The Government of Poland's arrangements for marking the occasion include an international symposium, restoration of her house in Warsaw, publications and films, and the Agency is happy to collaborate. This article, from a distinguished Austrian scientist, indicates how her work was carried out in an atmosphere of co-operation between scientists of many nations

  12. Pediatric Charcot-Marie-Tooth disease.

    Science.gov (United States)

    Jani-Acsadi, Agnes; Ounpuu, Sylvia; Pierz, Kristan; Acsadi, Gyula

    2015-06-01

    Heritable diseases of the peripheral nerves (Charcot-Marie-Tooth disease [CMT]) affect the motor units and sensory nerves, and they are among the most prevalent genetic conditions in the pediatric patient population. The typical clinical presentation includes distal muscle weakness and atrophy, but the severity and progression are largely variable. Improvements in supportive treatment have led to better preservation of patients' motor functions. More than 80 genes have been associated with CMT. These genetic discoveries, along with the developments of cellular and transgenic disease models, have allowed clinicians to better understand the disease mechanisms, which should lead to more specific treatments. Copyright © 2015 Elsevier Inc. All rights reserved.

  13. Friendship in the Life and Work of Mary Wollstonecraft: The Making of a Liberal Feminist Tradition

    DEFF Research Database (Denmark)

    Pedersen, Joyce Senders

    2008-01-01

    Mary Wollstonecrafts venskaber placeres indenfor en liberal fortolkningstradition . Udgivelsesdato: Spring 2008......Mary Wollstonecrafts venskaber placeres indenfor en liberal fortolkningstradition . Udgivelsesdato: Spring 2008...

  14. Marie and Pierre Curie and radium: history, mystery, and discovery.

    Science.gov (United States)

    Mould, R F

    1999-09-01

    Commencing with Marie Curie's early life in Poland and the discovery of radium in the rue l'Homond "shed" in Paris in 1898, this paper includes some little known facts. It ends with some unusual uses of and claims for radium, and finally, because Medical Physics is an American journal, details are included of Marie Curie's two visits to the USA.

  15. Mari Koger : "Arhitekte on palju. Tuleb leida õige" / Gitte Hint

    Index Scriptorium Estoniae

    Hint, Gitte

    2003-01-01

    Mari Koger (sünd. 1973) kodu kujundamisest, planeerimisest, valgustusest, värvidest, suhtlemisest kliendiga. Mari Kogerist, loetletud tema tehtud ühiskondlike ruumide sisekujundused aastast 2002. M. Koger töötab Boom.ee OÜ-s. Ill.: M. Kogeri värv. portree

  16. Eisma sadamahoone = Eisma port building / Mari Kurismaa ; kommenteerinud Krista Aren

    Index Scriptorium Estoniae

    Kurismaa, Mari, 1956-

    2015-01-01

    Eluruumid Eisma sadamahoones (Eisma küla, Vihula vald, Lääne-Virumaa). Sisekujunduse autorid Mari Kurismaa, Indrek Allmann; arhitekt Indrek Allmann (AB Pluss). Eesti Sisearhitektide Liidu aastapreemia 2014/2015 parima kodu eest. Lühidalt Mari Kurismaast ja Indrek Allmannist

  17. Spaces of Modernism: Ljubica Marić in Context

    Czech Academy of Sciences Publication Activity Database

    Bajgarová, Jitka

    2010-01-01

    Roč. 47, č. 1 (2010), s. 109-111 ISSN 0018-7003. [Spaces of Modernism: Ljubica Marić in Context. Beograd, 05.11.2009-07.11.2009] Institutional research plan: CEZ:AV0Z90580513 Keywords : Ljubica Marić * Serbian composer Subject RIV: AL - Art, Architecture, Cultural Heritage

  18. Causes of Charcot-Marie-Tooth Disease (CMT)

    Science.gov (United States)

    ... for MDA Blog Donate Search MDA.org Close Charcot-Marie-Tooth Disease (CMT) Share print email share facebook twitter ... More than 30 genes have been implicated in Charcot-Marie-Tooth disease (CMT). In different types of CMT, peripheral ...

  19. Can We Predict the Winner in a Market with Network Effects? Competition in Cryptocurrency Market

    Directory of Open Access Journals (Sweden)

    Neil Gandal

    2016-07-01

    Full Text Available We analyze how network effects affect competition in the nascent cryptocurrency market. We do so by examining early dynamics of exchange rates among different cryptocurrencies. While Bitcoin essentially dominates this market, our data suggest no evidence of a winner-take-all effect early in the market. Indeed, for a relatively long period, a few other cryptocurrencies competing with Bitcoin (the early industry leader appreciated much more quickly than Bitcoin. The data in this period are consistent with the use of cryptocurrencies as financial assets (popularized by Bitcoin, and not consistent with winner-take-all dynamics. Toward the end of our sample, however, things change dramatically. Bitcoin appreciates against the USD, while other currencies depreciate against the USD. The data in this period are consistent with strong network effects and winner-take-all dynamics. This trend continues at the time of writing.

  20. Genomic insights into metabolic potentials of two simultaneous aerobic denitrification and phosphorus removal bacteria Achromobacter sp. GAD3 and Agrobacterium sp. LAD9.

    Science.gov (United States)

    Liu, Shufeng; Chen, Qian; Ma, Tao; Wang, Ming; Ni, Jinren

    2018-02-01

    Bacteria capable of simultaneous aerobic denitrification and phosphorus removal (SADPR) are promising to establish novel one-stage wastewater treatment systems. Nevertheless, insights into metabolic potentials of SADPR related bacteria are limited. Here, comprehensive metabolic models of two efficient SADPR bacteria Achromobacter sp. GAD3 and Agrobacterium sp. LAD9 were yielded for the first time by high-throughput genome sequencing. With succinate as the preferred carbon source, both strains employed a complete TCA cycle as the major carbon metabolism for various organic acids and complex carbon oxidation potentials. Complete and truncated aerobic denitrification routes were confirmed in GAD3 and LAD9, respectively, facilitated by all major components of electron transfer chain via oxidative phosphorylation. Comparative genome analysis revealed distinctive ecological niches involved in denitrifying potential among different phylogenetic clades within Achromobacter and Agrobacterium. Excellent phosphorus removal capacities were contributed by inorganic phosphate uptake, polyphosphate synthesis and phosphonate metabolism. Additionally, the physiology of GAD3/LAD9 is different to that displayed by most available polyphosphate accumulating organisms (PAOs), and reveals both strains to be more versatile, carrying out diverse organics degradation potentials and outstanding SADPR capacity within a single organism. The functional explorations of SADPR bacteria broaden their significant application prospects in concurrent carbon and nutrients removal aerobically. © FEMS 2018. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  1. Roadmap to MaRIE March 2015

    Energy Technology Data Exchange (ETDEWEB)

    Barnes, Cris William [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2015-03-30

    Los Alamos National Laboratory’s proposed MaRIE facility is slated to introduce the world’s highest energy hard x-ray free electron laser (XFEL). As the light source for the Matter-Radiation Interactions in Extremes experimental facility (MaRIE), the 42-keV XFEL, with bursts of x-ray pulses at gigahertz repetition for studying fast dynamical processes, will help accelerate discovery and design of the advanced materials needed to meet 21st-century national security and energy security challenges. Yet the science of free-electron lasers has a long and distinguished history at Los Alamos National Laboratory (LANL), where for nearly four decades Los Alamos scientists have been performing research, design, development, and collaboration work in FEL science. The work at Los Alamos has evolved from low-gain amplifier and oscillator FEL development to highbrightness photoinjector development, and later, self-amplified spontaneous emission (SASE) and high-gain amplifier FEL development.

  2. Assessing and identifying transitional losers and winners in the Serbian society

    Directory of Open Access Journals (Sweden)

    Trifunović Vesna

    2012-01-01

    Full Text Available This paper presents ways to assess and evaluate losers and winners in the Serbian transitional society, through several concrete examples. Therefore, the paper is a follow-up of the manuscript published in the previous Bulletin of Institute of ethnography, and fits into the theoretical framework already stated. The main indicator of a variety of assessment regarding losers and winners is found among comments made by visitors of relevant Internet web sites, referring to news about societal problems and issues during the process of post-socialist transformation. These are directly linked with a phenomenon of losing or winning in transition, such as unemployment, poverty, criminal, success, failure, wealth, and power. Hence, news from two internet sites "Blic" i "B92" served as a source, while their visitors ‘commentaries to the particular news served in the analysis. Specific news was used to define a particular problem or issue, and the commentaries were seen as reactions to the news. The commentaries contain readers’ attitudes, assessment of particular issues and discourses overview. These comments were chosen based on whether they refer directly to the problem of losing/winning in transition, and on their diversity regarding assessment of the problem itself. At the same time, posted texts on the mentioned sites were not unbiased, and they can also serve to identify losers and winners of transition. Defining a category of losers or winners in transition is a complex issue of various interpretations and constructions, making thus a discrepancy in attributed meanings among the members of Serbian society. Controversy and contradictions in expressed attitudes about losers and winners, as well as understanding of these categories, could be explained by various aspects and outlooks held. In brief, an existing particular social heteroglossia, assumes many different readings and attitudes regarding the categories, caused by various factors. The

  3. Louisiana SIP: LAC 33:III Ch 2147. Limiting Volatile Organic Compound (VOC) Emissions from Reactor Processes and Distillation Operations in Synthetic Organic Chemical manufacturing Industry (SOCMI); SIP effective 2011-08-04 (LAd34) to 2017-09-27

    Science.gov (United States)

    Louisiana SIP: LAC 33:III Ch 2147. Limiting Volatile Organic Compound (VOC) Emissions from Reactor Processes and Distillation Operations in Synthetic Organic Chemical manufacturing Industry (SOCMI); SIP effective 2011-08-04 (LAd34) to 2017-09-27

  4. Lad os slagte Udkantsdanmark

    DEFF Research Database (Denmark)

    Høst, Jeppe Engset

    2015-01-01

    En ny journalistisk genre har ramt os. Det er udkantsgotikken. Med dramatiske historier om forfald, armod og affolkning, fortælles der vidt og bredt om landsbydød og masseflugt fra udkanten. Historierne har masser af saftige ord, er rige på associationer, og vinklingen rummer dødskampen, som...

  5. Leukocyte Adhesion Deficiency (LAD)

    Science.gov (United States)

    ... Publications Help Archive Site Map Información en español Employee Information Connect with NIAID Facebook Twitter Linkedin Google+ Youtube Flickr Instagram Pinterest Email Website Policies & Notices ...

  6. The life and legacy of Marie Curie.

    Science.gov (United States)

    Rockwell, Sara

    2003-01-01

    Marie Curie was a remarkable woman whose discoveries broke new ground in physics and chemistry and also opened the door for advances in engineering, biology, and medicine. She broke new ground for women in science: she was, for example, the first woman to receive a doctor of science degree in France, the first woman to win Nobel Prize, the first woman to lecture at the Sorbonne, the first person to win two Nobel Prizes, and the first Nobel Laureate whose child also won a Nobel Prize. Her life offers insights into the changing role of women in science and academia over the past century. It also offers examples of many ways in which scientists can, and should, work to improve the educational programs and career opportunities available to those who follow in their footsteps.

  7. Charcot-Marie-Tooth disease in Denmark

    DEFF Research Database (Denmark)

    Vaeth, Signe; Vaeth, Michael; Andersen, Henning

    2017-01-01

    OBJECTIVES: Charcot-Marie-Tooth disease (CMT) is the most common inherited disorder of the peripheral nervous system, yet no studies have compared the mortality in patients with CMT with that of the general population, and prevalence estimates vary considerably. We performed a nationwide register....... The prevalence was estimated by 31 December 2012, and the incidence rate was calculated based on data from 1988 to 2012. We calculated a standardised mortality ratio (SMR) and an absolute excess mortality rate (AER) stratified according to age categories and disease duration. RESULTS: A total of 1534 patients...... a significantly higher SMR in cases below 50 years of age, and in cases with disease duration of more than 10 years. CONCLUSIONS: We found a reduced life expectancy among patients diagnosed with CMT. To our knowledge, this is the first study of CMT to use nationwide register-based data, and the first to report...

  8. Michel Marie e a poesia do olhar

    OpenAIRE

    - FAMECOS/PUCRS, Eduardo Portanova

    2008-01-01

    Professor da Universidade Sorbonne (III) e autor de livros já incorporados à cultura cinematográfica no âmbito acadêmico, como “Dicionário teórico e crítico de cinema” e “A estética do filme”, ambos em coautoria com Jacques Aumont, Michel Marie pode ser considerado, hoje, um dos principais teóricos franceses e mundiais da história do cinema. Acaba, ainda, de lançar, junto com Laurent Jullier, “Lires les images de cinéma”, pela Larousse, no qual apresenta as ferramentas da análise fílmica, con...

  9. Mariátegui: un marxista nietzscheano

    Directory of Open Access Journals (Sweden)

    Alfonso Ibáñez

    2001-01-01

    Full Text Available En la conmemoración de la muerte de Nietzsche, ocurrida hace un siglo, conviene tener muy en cuenta su recepción entre nosotros. Es el caso de José Carlos Mariátegui, quien desde posiciones que se podrían ver como antagónicas a las del pensador alemán, hace una asimilación original de motivos nietzscheanos dentro de su concepción revolucionaria. A tal punto que se podría decir que su “marxismo nietzscheano” es el que le posibilita la elaboración del proyecto de un “socialismo indoamericano”. ¿De la confrontación con la “filosofía del martillo” surgirán nuevas propuestas alternativas en el milenio que inauguramos?

  10. Update on Charcot-Marie-Tooth Disease

    Science.gov (United States)

    Patzkó, Ágnes; Shy, Michael E.

    2011-01-01

    Charcot-Marie-Tooth disease (CMT) disease encompasses a genetically heterogeneous group of inherited neuropathies, also known as hereditary motor and sensory neuropathies. CMT results from mutations in more than 40 genes expressed in Schwann cells and neurons causing overlapping phenotypes. The classic CMT phenotype reflects length-dependent axonal degeneration characterized by distal sensory loss and weakness, deep tendon reflex abnormalities, and skeletal deformities. Recent articles have provided insight into the molecular pathogenesis of CMT, which, for the first time, suggest potential therapeutic targets. Although there are currently no effective medications for CMT, multiple clinical trials are ongoing or being planned. This review will focus on the underlying pathomechanisms and diagnostic approaches of CMT and discuss the emerging therapeutic strategies. PMID:21080241

  11. Winners and Losers in the Finfish Trade on Mafia Island: A Value ...

    African Journals Online (AJOL)

    Winners and Losers in the Finfish Trade on Mafia Island: A Value Chain Analysis. 153 further achieved for some actors in the chain by reducing its length. There is growing concern regarding the continued deprivation of the fishing communities and the need to improve their livelihoods and livelihood diversification. The.

  12. Winners of the First 1960 Televised Presidential Debate between Kennedy and Nixon.

    Science.gov (United States)

    Kraus, Sidney

    1996-01-01

    Reviews the events, studies, and comments (from 1960 to the present) regarding the controversial question of who won the first 1960 televised debate between John F. Kennedy and Richard M. Nixon. Supports the view that, for television viewers, Kennedy was the winner, whereas radio listeners gave Nixon the edge. (SR)

  13. The Great Unknown: Daniel Handler Interviews National Book Award-Winner Judy Blundell

    Science.gov (United States)

    Handler, Daniel

    2009-01-01

    This article presents an interview with National Book Award-winner Judy Blundell. For nearly 20 years, Blundell has toiled in anonymity, turning out more than 100 mysteries, romances, and media tie-ins under various pen names, such as Jude Watson. But in mid-November, the writer-for-hire was suddenly shoved into the spotlight. That's when "What I…

  14. "the winners" and "the losers" in a globalized world: the case of Amazon rainforest

    OpenAIRE

    Majewska, N.

    2012-01-01

    The present paper by using the approach of "the winners" and "the losers" both in economy and environment emphasizes the multiple outcomes that can emerge as a result of interaction between the eager will of profit over the need to protect the environment. The case of the "Amazonian rainforest from Brazil" was taken as an illustrative example

  15. ACCE/ACS National Educator and Leader of the Year Winners: AEC Congratulates These Outstanding Educators

    Science.gov (United States)

    Australian Educational Computing, 2012

    2012-01-01

    This article presents the ACCE/ACS National Educator and Leader of the Year winners. Anne Mirtschin is the recipient of the ACCE/ACS 2012 Educator of the Year Award. Mirtschin is an innovative teacher at Hawkesdale P-12 College a small rural school that is isolated culturally and geographically. She uses online tools and technology to create…

  16. Thirty Years After: The Lives of Former Winners of Mathematical Olympiads.

    Science.gov (United States)

    Karp, Alexander

    2002-01-01

    This follow-up study surveyed earlier winners of the St. Petersburg (Russia) mathematical Olympiad in 1991 (n=58) and 2001 (n=30). Findings are detailed concerning respondents' academic degrees, employment, publications, schools attended, and perceived quality of mathematical education. Respondents' views about education were conservative and…

  17. National Academic Award Winners over Time: Their Family Situation, Education and Interpersonal Relations

    Science.gov (United States)

    Sekowski, Andrzej; Siekanska, Malgorzata

    2008-01-01

    The article presents the results of a study focusing on the family situation, education and interpersonal relations of adults (26-35 years old) who in their adolescence (16-19 years old) displayed exceptional giftedness. One group of those surveyed were national academic award winners (90). The control group consisted of 90 people of no…

  18. Marie Curie and Mildred Dresselhaus, inspirations to women in science

    Science.gov (United States)

    Murray, Cherry

    The physics community lost the celebrated physicist Mildred Dresselhaus on February 20, 2017. Millie was originally scheduled to give this talk describing how fascination with Marie Curie's biography propelled her into science at a young age. I will talk about the many parallels I see between the two pioneers: Marie Curie, born in 1867, who was an inspiration to a young Millie, and Millie, born in 1930, who was an inspiration to me, as well as many more women and men in science. I will also describe some of Millie's research in condensed matter physics making use of radioactivity and the heritage of Marie Curie.

  19. Ämari baas sobib USA-le ja brittidele

    Index Scriptorium Estoniae

    2013-01-01

    Eelmisel nädalal Eestit külastanud USA ja Ühendkuningriigi sõjalised esindajad NATO juures kindralleitnandid David R. Hogg ja Christopher Harper kinnitasid, et on valmis oma lennukeid Ämari baasist opereerima

  20. Marie Curie's Doctoral Thesis: Prelude to a Nobel Prize.

    Science.gov (United States)

    Wolke, Robert L.

    1988-01-01

    Traces the life and research techniques of Marie Curie's doctoral dissertation leading to the discovery and purification of radium from ore. Reexamines the discoveries of other scientists that helped lead to this separation. (ML)

  1. A bust of Marie Sklodowska Curie at CERN

    CERN Multimedia

    CERN PhotoLab

    1979-01-01

    The Polish Deputy Minister of Energy and Nuclear Power, J. Felicki, presented the Directors General with a bust of Mme Marie Sklodowska Curie on behalf of physicists of Poland (CERN Courier 19 (1979) 164).

  2. Marie Curie: In the laboratory and on the battlefield

    International Nuclear Information System (INIS)

    Badash, Lawrence

    2003-01-01

    This year is the centennial of the Nobel Prize in Physics shared by Henri Becquerel and the Curies for their pioneering work on radioactivity. But Marie Curie's contribution to the medical use of x rays is not widely known

  3. A jolly good call for Marie Curie Fellows

    CERN Multimedia

    2009-01-01

    A new funding opportunity to train young researchers has just been announced by the European Commission. One of the calls within FP7 Marie Curie Actions requests proposals for Initial Training Network (ITN) projects, with a deadline of 22 December 2009. Project proposals are strongly encouraged at CERN and authors can receive support and guidance from the Marie Curie Steering Group. Winnie Wong: "I wouldn’t have considered a PhD if I hadn’t been a Marie Curie fellow" Dan Savu: "It’s the best of both worlds: training plus working in an international organisation" ITN projects have one key aim: training. Academic and industrial partners work together to form a network to recruit and train Marie Curie Fellows. Fellows are young researchers (typically PhD-level) from any country who combine project-based research with tailor-made training programmes, ...

  4. Exploring the Universe with John Milton and Mary Shelley.

    Science.gov (United States)

    Poston, David

    1989-01-01

    Presents an approach to teaching John Milton's "Paradise Lost" in conjunction with Mary Shelley's "Frankenstein." Notes that a study of these works stimulates vigorous discussions on theological and moral issues, human nature, and the cultural past and future. (MM)

  5. Deployment of Autonomous GPS Stations in Marie Byrd Land, Antartica

    Science.gov (United States)

    Donnellan, A.; Luyendyk, B.; Smith, M.; Dace, G.

    1999-01-01

    During the 1998-1999 Antarctic field season, we installed three autonomous GPS stations in Marie Byrd Land, West Antarctica to measure glacio-isostatic rebound and rates of spreading across the West Antartic Rift System.

  6. ODYSSEY MARS MARIE CALIBRATED DATA V1.0

    Data.gov (United States)

    National Aeronautics and Space Administration — The MARIE (Martian Radiation Environment Experiment), aboard the 2001 Mars Odyssey spacecraft, was launched on April 7, 2001, and arrived at Mars on October 24,...

  7. Need sinihallid veised... : Marie Under ja Villem Ridala / Ruth Mirov

    Index Scriptorium Estoniae

    Mirov, Ruth, 1928-

    2008-01-01

    Vaadeldakse kahte ühest ja samast muistendist - merest tõusnud lehmakarjast - inspireeritud ballaadi: Marie Underi "Merilehmi" (ilm. kogus "Õnnevarjutus", 1929) ja Villem Ridala "Sinist karja" (ilm. kogus "Sinine kari", 1930)

  8. Anne-Marie Sargueil: ilu on kasulik / intervjueerinud Emilie Toomela

    Index Scriptorium Estoniae

    Sargueil, Anne-Marie

    2015-01-01

    Prantsuse Disainiinstituudi juht Anne-Marie Sargueil rääkis prantsuse ja skandinaavia disainist, prantslaste disainieelistustest, uutest suundadest disaini valdkonnas, Eesti Tarbekunsti- ja Disainimuuseumis avatud näitusest "20 prantsuse disainiikooni"

  9. Else-Marie Osmundsen: Workers' Education and the Environment.

    Science.gov (United States)

    Labour Education, 1991

    1991-01-01

    Else-Marie Osmundsen, manager of an International Labour Office project, "Workers' Education and the Environment," discusses the importance of union participation in environmental programs. She describes the implementation of the project in the Caribbean. (JOW)

  10. Mary Tyler Moore Helps Launch NIH MedlinePlus Magazine

    Science.gov (United States)

    ... Issues Mary Tyler Moore Helps Launch NIH MedlinePlus Magazine Past Issues / Winter 2007 Table of Contents For ... Javascript on. Among those attending the NIH MedlinePlus magazine launch on Capitol Hill were (l-r) NIH ...

  11. ODYSSEY MARS MARIE REFORMATTED RAW DATA V1.0

    Data.gov (United States)

    National Aeronautics and Space Administration — The MARIE (Martian Radiation Environment Experiment), aboard the 2001 Mars Odyssey spacecraft, was launched on April 7, 2001, and arrived at Mars on October 24,...

  12. Raamatukogu esisele kerkib kevadel Marie Underi kuju / Andres Eilart

    Index Scriptorium Estoniae

    Eilart, Andres

    2009-01-01

    Skulptor Mati Karminil ja arhitekt Tiit Trummalil valmib valgest marmorist mälestusmärk Marie Underile. Kuju püstitatakse 2010. a. kevadel Eesti Rahvusraamatukogu ette. Alale on kavandatud ka veekaskaadid

  13. Effects of stem cell factor on hypoxia-inducible factor 1 alpha accumulation in human acute myeloid leukaemia and LAD2 mast cells.

    Directory of Open Access Journals (Sweden)

    Bernhard F Gibbs

    Full Text Available Stem cell factor (SCF is a hematopoietic growth factor that exerts its activity by signalling through the tyrosine kinase receptor known as Kit or CD117. SCF-Kit signalling is crucial for the survival, proliferation and differentiation of hematopoietic cells of myeloid lineage. Furthermore, since myeloid leukaemia cells express the Kit receptor, SCF may play an important role in myeloid leukaemia progression too. However, the mechanisms of this pathophysiological effect remain unclear. Recent evidence shows that SCF triggers accumulation of the inducible alpha subunit of hypoxia-inducible factor 1 (HIF-1 in hematopoietic cells--a transcription complex that plays a pivotal role in cellular adaptation to low oxygen availability. However, it is unknown how SCF impacts on HIF-1α accumulation in human myeloid leukaemia and mast cells. Here we show that SCF induces HIF-1α accumulation in THP-1 human myeloid leukaemia cells but not in LAD2 mast cells. We demonstrated that LAD2 cells have a more robust glutathione (GSH-dependent antioxidative system compared to THP-1 cells and are therefore protected against the actions of ROS generated in an SCF-dependent manner. BSO-induced GSH depletion led to a significant decrease in HIF-1α prolyl hydroxylase (PHD activity in THP-1 cells and to near attenuation of it in LAD2 cells. In THP-1 cells, SCF-induced HIF-1α accumulation is controlled via ERK, PI3 kinase/PKC-δ/mTOR-dependent and to a certain extent by redox-dependent mechanisms. These results demonstrate for the first time an important cross-talk of signalling pathways associated with HIF-1 activation--an important stage of the myeloid leukaemia cell life cycle.

  14. Thoroughly Post-Modern Mary. A Biographic Narrative Interview With Mary Gergen

    Directory of Open Access Journals (Sweden)

    Kip Jones

    2004-09-01

    Full Text Available Method: The Biographic Narrative Interpretive Method (Prue CHAMBERLAYNE, Joanna BORNAT & Tom WENGRAF, 2000; Tom WENGRAF 2001; Gabriele ROSENTHAL 2004; Kip JONES 2004 uses an interview technique in the form of a single, initial narrative-inducing question (minimalist-passive, for example, "Tell me the story of your life," to elicit an extensive, uninterrupted narration. This shift encompasses willingness on the part of the researcher to cede "control" of the interview scene to the interviewee and assume the posture of active listener/audience participant. A follow-up sub-session can then be used to ask additional questions, but based only on what the interviewee has said in the first interview and using her/his words and phrases in the same order. Through hypothesising how the lived life informs the told story, the case history is then finally constructed from the two separate threads of the "lived life" and the "told story." In this paper, the "lived life" and "told story" are presented in a "raw" form with the further involvement of the reader in mind. The story has not been "analysed" by the interviewer, but left open and transparent. Still, the production of the story becomes the creative output and social construction of both the storyteller and the interviewer (the performer and the audience and, in this case particularly, one story of many stories that could have been told by the person interviewed. Routine facts are often back-grounded by the narrator through the use of this method in favour of spontaneity in the storytelling and the creation of meaningful life metaphors. In this way, the personal journey to "who the interviewee is today" is described, rather than merely a list of accomplishments. The Lived Life: Mary GERGEN (née McCANNEY was born in 1938. The first part of her childhood was spent in the small town of Balaton, Minnesota. She subsequently moved with her family to Minneapolis when she was 12. She attended a suburban middle

  15. A commentary on ‘Little Hooliganz: The Inside Story of Glamorous Lads, Football Hooligans and Post-Subculturalism’ by Professor Steve Redhead

    OpenAIRE

    Pearson, Dr Geoff

    2011-01-01

    Issue 8(2) of this Journal included the article, ‘Little Hooliganz: The Inside Story of Glamorous Lads, Football Hooligans and Post-Subculturalism’ by Prof Steve Redhead. The author is professor of Sport and Media Cultures at the Chelsea School, Brighton University, and has been carrying out research on football fan sub-cultures, including but not limited to the issue of ‘football hooliganism’, for over 20 years. He describes his work on hooliganism as part of the ‘cluster’ of postmodern sub-...

  16. Referrals to the Marie Curie nursing service in North Yorkshire.

    Science.gov (United States)

    Hanratty, B; Feather, J; Ward, C

    2000-01-01

    District and Marie Curie nurses participated in a small-scale study to describe referrals to a Marie Curie service in one English health district over a 3-month period. The number of new patients referred was small; they were geographically clustered and had widely differing life expectancies. Anecdotal reports of difficulties with the 'Nurselink' referral system were not confirmed, and in situations where the system was in operation, Marie Curie nurses were more likely to speak directly to the referring nurse. The most frequently cited reason for referral was general nursing needs; however, Marie Curie nurses felt that they were most often involved to provide family support. These findings suggest that there may not be a shared understanding of the Marie Curie nurse's role, and that equity in community palliative nursing care merits examination. Defining and publicizing the role of the Marie Curie nurse, providing guidance for referrals and prioritizing communication between professionals are proposed not only to enhance the service locally but to ensure that the service is available to all. This article illustrates the value of research to identify ways to improve service delivery.

  17. The Comparison Between Two Surgical Methods for Left Internal Mammary Artery (LIMA) Anastomosis on Left Anterior Descending (LAD) Artery in Patients with Severe Diffuse Lesions: Short to Mid-Term Results.

    Science.gov (United States)

    Zarrabi, Khalil; Dehghani, Pooyan; Abdi Ardekani, Alireza; Zarrabi, Mohammad Amin; Zolghadrasli, Abdoali

    2015-01-01

    Coronary artery disease is the leading cause of death worldwide. In this study, we compared two surgical methods of left internal mammary artery (LIMA) anastomosis on left anterior descending (LAD) artery in patients with severe diffuse lesions. A total of 40 patients were included in our study and randomly assigned into two groups. In group A, after a long arteriotomy on LAD, the posterior surface of left internal mammary artery (LIMA) was opened by the same length and was anastomosed along the LAD course through normal and diseased parts. In group B instead of complete opening of LAD, a small arteriotomy was done only in areas where the wall of the vessel was nearly normal (especially the anterolateral wall), and LIMA was anastomosed to these areas in a sequential (Jump) method. The patients were then followed for post-operation results. The two groups showed equal results regarding early mortality, post-operation bleeding, and infection, pleural and pericardial effusion. There were two cases of myocardial infarction (MI) in group A with one mortality after 18 months, while no MI was reported in group B. Group B demonstrated significantly superior results regarding the rise in ejection fraction and the improvement in functional class. In this study it was demonstrated that diffuse coronary artery lesions of LAD should be preferably operated using LIMA with the sequential-jump anastomoses method and the surgeon should avoid long arteriotomy with single long anastomosis because of lower chance of long-term patency.

  18. The Comparison Between Two Surgical Methods for Left Internal Mammary Artery (LIMA Anastomosis on Left Anterior Descending (LAD Artery in Patients with Severe Diffuse Lesions: Short to Mid-Term Results.

    Directory of Open Access Journals (Sweden)

    Khalil Zarrabi

    2015-06-01

    Full Text Available Coronary artery disease is the leading cause of death worldwide. In this study, we compared two surgical methods of left internal mammary artery (LIMA anastomosis on left anterior descending (LAD artery in patients with severe diffuse lesions. A total of 40 patients were included in our study and randomly assigned into two groups. In group A, after a long arteriotomy on LAD, the posterior surface of left internal mammary artery (LIMA was opened by the same length and was anastomosed along the LAD course through normal and diseased parts. In group B instead of complete opening of LAD, a small arteriotomy was done only in areas where the wall of the vessel was nearly normal (especially the anterolateral wall, and LIMA was anastomosed to these areas in a sequential (Jump method. The patients were then followed for post-operation results. The two groups showed equal results regarding early mortality, post-operation bleeding, and infection, pleural and pericardial effusion. There were two cases of myocardial infarction (MI in group A with one mortality after 18 months, while no MI was reported in group B. Group B demonstrated significantly superior results regarding the rise in ejection fraction and the improvement in functional class. In this study it was demonstrated that diffuse coronary artery lesions of LAD should be preferably operated using LIMA with the sequential-jump anastomoses method and the surgeon should avoid long arteriotomy with single long anastomosis because of lower chance of long-term patency.

  19. Biased Random-Key Genetic Algorithms for the Winner Determination Problem in Combinatorial Auctions.

    Science.gov (United States)

    de Andrade, Carlos Eduardo; Toso, Rodrigo Franco; Resende, Mauricio G C; Miyazawa, Flávio Keidi

    2015-01-01

    In this paper we address the problem of picking a subset of bids in a general combinatorial auction so as to maximize the overall profit using the first-price model. This winner determination problem assumes that a single bidding round is held to determine both the winners and prices to be paid. We introduce six variants of biased random-key genetic algorithms for this problem. Three of them use a novel initialization technique that makes use of solutions of intermediate linear programming relaxations of an exact mixed integer linear programming model as initial chromosomes of the population. An experimental evaluation compares the effectiveness of the proposed algorithms with the standard mixed linear integer programming formulation, a specialized exact algorithm, and the best-performing heuristics proposed for this problem. The proposed algorithms are competitive and offer strong results, mainly for large-scale auctions.

  20. Forecasting a winner for Malaysian Cup 2013 using soccer simulation model

    Science.gov (United States)

    Yusof, Muhammad Mat; Fauzee, Mohd Soffian Omar; Latif, Rozita Abdul

    2014-07-01

    This paper investigates through soccer simulation the calculation of the probability for each team winning Malaysia Cup 2013. Our methodology used here is we predict the outcomes of individual matches and then we simulate the Malaysia Cup 2013 tournament 5000 times. As match outcomes are always a matter of uncertainty, statistical model, in particular a double Poisson model is used to predict the number of goals scored and conceded for each team. Maximum likelihood estimation is use to measure the attacking strength and defensive weakness for each team. Based on our simulation result, LionXII has a higher probability in becoming the winner, followed by Selangor, ATM, JDT and Kelantan. Meanwhile, T-Team, Negeri Sembilan and Felda United have lower probabilities to win Malaysia Cup 2013. In summary, we find that the probability for each team becominga winner is small, indicating that the level of competitive balance in Malaysia Cup 2013 is quite high.

  1. Hierarchical Winner-Take-All Particle Swarm Optimization Social Network for Neural Model Fitting

    Science.gov (United States)

    Coventry, Brandon S.; Parthasarathy, Aravindakshan; Sommer, Alexandra L.; Bartlett, Edward L.

    2016-01-01

    Particle swarm optimization (PSO) has gained widespread use as a general mathematical programming paradigm and seen use in a wide variety of optimization and machine learning problems. In this work, we introduce a new variant on the PSO social network and apply this method to the inverse problem of input parameter selection from recorded auditory neuron tuning curves. The topology of a PSO social network is a major contributor to optimization success. Here we propose a new social network which draws influence from winner-take-all coding found in visual cortical neurons. We show that the winner-take-all network performs exceptionally well on optimization problems with greater than 5 dimensions and runs at a lower iteration count as compared to other PSO topologies. Finally we show that this variant of PSO is able to recreate auditory frequency tuning curves and modulation transfer functions, making it a potentially useful tool for computational neuroscience models. PMID:27726048

  2. Highlights from e-EPS: the 2015 EPS High Energy Physics Prize winners

    CERN Multimedia

    Thomas Lohse, e-EPS News

    2015-01-01

    The EPS High Energy Physics Division announces the winners of its 2015 prizes, which will be awarded at the Europhysics Conference on High-Energy Physics (EPS-HEP 2015), Vienna (Austria) 22−29 July. Many people from CERN were among the winners.   The 2015 High Energy and Particle Physics Prize, for an outstanding contribution to High Energy Physics, is awarded to James D. Bjorken “for his prediction of scaling behaviour in the structure of the proton that led to a new understanding of the b interaction”, and to Guido Altarelli, Yuri L. Dokshitzer, Lev Lipatov, and Giorgio Parisi “for developing a probabilistic field theory framework for the dynamics of quarks and gluons, enabling a quantitative understanding of high-energy collisions involving hadrons”. The 2015 Giuseppe and Vanna Cocconi Prize, for an outstanding contribution to Particle Astrophysics and Cosmology in the past 15 years, is awarded to Francis Halzen “for his visiona...

  3. Ecotoxicological characterisation and ecofriendlier alternative formulations of a commercial herbicide (Winner Top®)

    OpenAIRE

    Queirós, Libânia Sofia Seixas

    2016-01-01

    Tem-se assistido a um uso potencialmente abusivo de produtos fitofarmacêuticos, com consequentes efeitos ambientais. Assim, o desenvolvimento de produtos mais eficazes e amigos do ambiente é um dos grandes desafios da atualidade. Neste contexto, este trabalho teve como principais objetivos: (i) avaliar a toxicidade dos formulantes ou adjuvantes utilizados nas formulações dos produtos comerciais, utilizando um herbicida modelo (Winner Top®), de forma a verificar se a designação destes ingredie...

  4. The result's dynamic of winners of men's open world powerlifting championships

    OpenAIRE

    Kotendzhy, L.; Stetsenko, A.

    2009-01-01

    The research is devoted to the problem of world mens powerlifting development. Performance of the winners of world mens powerlifting championships was analyzed, that enables to extend the notion of the laws of development and prospects of powerlifting. Productivity of world champions in powerlifting among men tends to body height. It testifi es to a permanent state of development of powerlifting. Dynamics of outcomes of world champions can depend on different factors.

  5. Recognizing 21. century citizenship: 1997 federal energy and water management award winners

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-12-31

    Energy is a luxury that no one can afford to waste, and many Federal government agencies are becoming increasingly aware of the importance of using energy wisely. Thoughtful use of energy resources is important, not only to meet agency goals, but because energy efficiency helps improve air quality. Sound facility management offers huge savings that affect the agency`s bottom line, the environment, and workplace quality. Hard work, innovation, and vision are characteristic of those who pursue energy efficiency. That is why the Department of Energy, Federal Energy Management Program (FEMP) is proud to salute the winners of the 1997 Federal Energy and Water Management Award. The 1997 winners represent the kind of 21st century thinking that will help achieve widespread Federal energy efficiency. In one year, the winners, through a combination of public and private partnerships, saved more than $100 million and 9.8 trillion Btu by actively identifying and implementing energy efficiency, water conservation, and renewable energy projects. The contributions of these individuals, small groups, and organizations are presented in this report.

  6. Join the CERN ISEF special award winners | 16 June - 3 p.m.

    CERN Multimedia

    2016-01-01

    Come and join the CERN ISEF special award winners at their lightning talks session on 16 June at 3.00 p.m. in the main auditorium.   The 2016 Intel ISEF CERN special award winners on stage with the selection committee on 17 May 2016 in Phoenix, Arizona, USA. (Picture: Society for Science and the Public) Between 11 and 17 June 2016, the ten finalists of the Intel International Science and Engineering Fair (ISEF) who won the CERN Special Award, will visit CERN to partake in various educational lectures. ISEF is the world's largest international pre-college science competition, with approximately 1,700 high school students from more than 75 countries taking part. They will present their projects in short 5 minutes lightning talks' sessions at the main auditorium on Thursday 16 June at 3 p.m. The award winners would be also very happy to have a chance to interact and discuss with you af...

  7. The conceptualization of winners and losers of transition in popular culture

    Directory of Open Access Journals (Sweden)

    Vesna Trifunović

    2016-02-01

    Full Text Available This paper is about the reconstruction of social presentations (picture, vision of losers and winners of transition based on the products of the popular culture such as the domestic TV series. The given picture was considered in the context of the 1990s, when those TV series were filmed and aired (broadcast, which means that they are typical, primarily, for the period of the so-called first transition. The analysis meant the abstracting one of the dominant themes in both TV series which refers to a certain family of ordinary people, faced with the everyday problems of the time their time, and those problems being mainly existential ones. The identification of the messages about losers and winners of transition, which was being sent through these TV series, was later continued by establishing a formula based on which the mentioned theme (subject was structured, and in the end completed by putting in connection the perceived oppostitions via semiotic square. The conceptualization of losers and winners of transition, which is the result of this paper, in no way implies that this vision of theirs is the only and the dominant one in this society. On the other hand, it certainly exists (existed in the given moment and context and as such it came to surface through domestic TV series as the product of popular culture, through which often widespread and popular attitudes of a society are expressed.

  8. Wingless signaling regulates winner/loser status in Minute cell competition.

    Science.gov (United States)

    Akai, Nanami; Igaki, Tatsushi; Ohsawa, Shizue

    2018-03-01

    Cells heterozygously mutant for a ribosomal protein gene, called Minute/+ mutants, are eliminated from epithelium by cell competition when surrounded by wild-type cells. Whereas several factors that regulate Minute cell competition have been identified, the mechanisms how winner/loser status is determined and thereby triggers cell competition are still elusive. To address this, we established two assay systems for Minute cell competition, namely (i) the CORE (competitive elimination of RpS3-RNAi-expressing cells) system in which RpS3-RNAi-expressing wing pouch cells are eliminated from wild-type wing disc and (ii) the SURE (supercompetition of RpS3-expressing clones in RpS3/+ tissue) system in which RpS3-over-expressing clones generated in RpS3/+ wing disc outcompete surrounding RpS3/+ cells. An ectopic over-expression screen using the CORE system identified Wg signaling as a critical regulator of Minute cell competition. Activation of Wg signaling in loser cells suppressed their elimination, whereas down-regulation of Wg signaling in loser cells enhanced their elimination. Furthermore, using the SURE system, we found that down-regulation of Wg signaling in winner cells suppressed elimination of neighboring losers. Our observations suggest that cellular Wg signaling activity is crucial for determining winner/loser status and thereby triggering Minute cell competition. © 2018 Molecular Biology Society of Japan and John Wiley & Sons Australia, Ltd.

  9. An Organizational Model for Excellence in Healthcare Delivery: Evidence From Winners of the Baldrige Quality Award.

    Science.gov (United States)

    Griffith, John R

    Winners of the Baldrige National Quality Award in healthcare have documented top quartile clinical outcomes and patient satisfaction across a variety of American communities and a full spectrum of care. Their results also show high levels of satisfaction among physicians, nurses, and other workers, as well as effective financial performance. The managerial methods they use-collectively, the Baldrige model-are consistent with organizational theory literature and are found across all winners. The winners have sustained excellence after winning and expanded it by acquisition of other healthcare organizations.The model differs substantially from traditional management approaches in healthcare delivery. It is a comprehensive program that emphasizes a shared focus on excellence, systematically responsive management, evidence-based medicine, multidimensional measures and negotiated goals, improvement of work processes, thorough training, and extensive rewards. The model could be expanded on a much larger scale. Doing so successfully would substantially improve the quality and cost of healthcare, as well as the satisfaction and commitment of care providers and other staff. The opportunity deserves further study and trial by large healthcare delivery systems, insurers, and consulting companies.

  10. Imitating winner or sympathizing loser? Quadratic effects on cooperative behavior in prisoners' dilemma games

    Science.gov (United States)

    Lu, Peng

    2015-10-01

    Cooperation is vital in human societies and therefore is widely investigated in the evolutionary game theory. Varieties of mechanisms have been proposed to overcome temptation and promote cooperation. Existing studies usually believe that agents are rational, but irrationalism such as emotions and feelings matters as well. Winner and loser are defined by their payoffs. In addition to admiring and imitating winners, the mechanism of sympathizing and imitating losers is introduced into the model as an alternative action rule, and each one plays the prisoners' dilemma game with eight neighbors under the influence of both irrationalism and rationalism. Rationalism refers to imitating winner to get highest payoff, and irrationalism means that people sympathize and adopt the actions of losers. As it is widely recognized that temptation reduces cooperation, this study focuses on the effect of sympathy on cooperation within a certain group or society. If it overcomes temptation that leads to defection, sympathy will be a powerful mechanism to promote cooperative behavior. Simulation results indicate that sympathy and temptation shares similar quadratic relationships with cooperation. Both sympathy and temptation undermine cooperation below their thresholds, and they both promote cooperation above their thresholds. Temptation not only reduces cooperation but also promote it as temptation goes beyond the threshold. Although sympathy is a good merit or human nature that is beneficial to society, a crisis or collapse of cooperation is inevitable when the sympathy propensity is relatively smaller. After cooperation reaches a minimal bottom, it then rises increasingly and dramatically, which brings a much brighter future of the society.

  11. Auditory function in children with Charcot-Marie-Tooth disease.

    Science.gov (United States)

    Rance, Gary; Ryan, Monique M; Bayliss, Kristen; Gill, Kathryn; O'Sullivan, Caitlin; Whitechurch, Marny

    2012-05-01

    The peripheral manifestations of the inherited neuropathies are increasingly well characterized, but their effects upon cranial nerve function are not well understood. Hearing loss is recognized in a minority of children with this condition, but has not previously been systemically studied. A clear understanding of the prevalence and degree of auditory difficulties in this population is important as hearing impairment can impact upon speech/language development, social interaction ability and educational progress. The aim of this study was to investigate auditory pathway function, speech perception ability and everyday listening and communication in a group of school-aged children with inherited neuropathies. Twenty-six children with Charcot-Marie-Tooth disease confirmed by genetic testing and physical examination participated. Eighteen had demyelinating neuropathies (Charcot-Marie-Tooth type 1) and eight had the axonal form (Charcot-Marie-Tooth type 2). While each subject had normal or near-normal sound detection, individuals in both disease groups showed electrophysiological evidence of auditory neuropathy with delayed or low amplitude auditory brainstem responses. Auditory perception was also affected, with >60% of subjects with Charcot-Marie-Tooth type 1 and >85% of Charcot-Marie-Tooth type 2 suffering impaired processing of auditory temporal (timing) cues and/or abnormal speech understanding in everyday listening conditions.

  12. Recent advances in Charcot-Marie-Tooth disease.

    Science.gov (United States)

    Baets, Jonathan; De Jonghe, Peter; Timmerman, Vincent

    2014-10-01

    This article focuses on recent advances in Charcot-Marie-Tooth disease, in particular additions to the genetic spectrum, novel paradigms in molecular techniques and an update on therapeutic strategies. Several new Charcot-Marie-Tooth disease-causing genes have been recently identified, further enlarging the genetic diversity and phenotypic variability, including: SBF1, DHTKD1, TFG, MARS, HARS, HINT1, TRIM1, AIFM1, PDK3 and GNB4. The increasing availability and affordability of next-generation sequencing technologies has ramped up gene discovery and drastically changed genetic screening strategies. All large-scale trials studying the effect of ascorbic acid in Charcot-Marie-Tooth 1A have now been completed and were negative. Efforts have been made to design more robust outcome-measures for clinical trials. Promising results with lonaprisan, curcumin and histone deacetylase 6 inhibitors have been obtained in animal models. Charcot-Marie-Tooth is the most common form of inherited peripheral neuropathy and represents the most prevalent hereditary neuromuscular disorder. The genetic spectrum spans more than 70 genes. Gene discovery has been revolutionized recently by new high-throughput molecular technologies. In addition, the phenotypic diversity has grown tremendously. This is a major challenge for geneticists and neurologists. No effective therapy is available for Charcot-Marie-Tooth. Several large trials with ascorbic acid were negative but research into novel compounds continues.

  13. Põhja-Eesti Regionaalhaigla X-korpus = North-Estonian Regional Hospital X-wing / Mari Kurismaa ; intervjueerinud Margit Mutso

    Index Scriptorium Estoniae

    Kurismaa, Mari, 1956-

    2011-01-01

    Tallinnas Sütiste tee 19 asuva haigla juurdeehitise sisekujundusest. Sisearhitekt Mari Kurismaa (Stuudio Kurismaa OÜ). Arhitektid Indrek Suigusaar, Vivian Oruvee (AB Pluss OÜ). Infograafika autor Mari Kaljuste

  14. Jean-Marie Dufour receives the Legion of Honour

    CERN Multimedia

    2001-01-01

    French Ambassador Philippe Petit (left) presents the cross of Knight of the Légion d'Honneur to Jean-Marie Dufour. On Friday 22 June, Jean-Marie Dufour, Head of CERN's Legal Service, was made Knight of the Legion of Honour by Ambassador Philippe Petit, at a ceremony held at the Permanent Mission of France in Geneva. Ambassador Petit is Permanent Representative of France at the United Nations and French delegate at CERN. He was awarded the decoration in recognition of his services. He has played an active part in all the great stages of CERN's development, in fact, ranging from its scientific programmes, to its establishment in its Host States, Switzerland and France, and its opening up to the wider world. The ceremony took place in the presence of Professor Luciano Maiani. The award is an honour to CERN, and the Organization takes this opportunity to convey its friendliest congratulations to Jean-Marie Dufour, a committed European.

  15. [Marie Heiberg. Üks naine kurbade silmadega] / Marko Mägi

    Index Scriptorium Estoniae

    Mägi, Marko

    2010-01-01

    Arvustus: Heiberg, Marie. Üks naine kurbade silmadega : Eesti luuletaja Marie Heibergi õnne ja valu, rõõmu ja mure lugu kirjades / [koostajad Iivi Lepik, Kirsten Simmo]. Tallinn : Eesti Teatri- ja Muusikamuuseum : SE & JS, 2010

  16. [Charcot-Marie-Tooth disease and bilateral vitritis].

    Science.gov (United States)

    Anaya-Pava, E J; Cárdenas-Hernández, R I

    2015-04-01

    We describe a patient diagnosed with Charcot-Marie-Tooth disease, with a 4 months history of bilateral decreased visual acuity and floaters. On examination, he had severe bilateral vitreous opacity and sectoral diffuse vascular sheathing. It could not be linked to some underlying aetiology and did not respond to oral steroids. Publications relating to ocular findings in patients with Charcot-Marie-Tooth disease exclude bilateral vitritis. In this case we were unable to test the association with another disease as the cause of vitritis. Copyright © 2013 Sociedad Española de Oftalmología. Published by Elsevier España, S.L.U. All rights reserved.

  17. Fast block matching algorithm based on the winner-update strategy.

    Science.gov (United States)

    Chen, Y S; Hung, Y P; Fuh, C S

    2001-01-01

    Block matching is a widely used method for stereo vision, visual tracking, and video compression. Many fast algorithms for block matching have been proposed in the past, but most of them do not guarantee that the match found is the globally optimal match in a search range. This paper presents a new fast algorithm based on the winner-update strategy which utilizes an ascending lower bound list of the matching error to determine the temporary winner. Two lower bound lists derived by using partial distance and by using Minkowski's inequality are described. The basic idea of the winner-update strategy is to avoid, at each search position, the costly computation of the matching error when there exists a lower bound larger than the global minimum matching error. The proposed algorithm can significantly speed up the computation of the block matching because: 1) computational cost of the lower bound we use is less than that of the matching error itself; 2) an element in the ascending lower bound list will be calculated only when its preceding element has already been smaller than the minimum matching error computed so far; 3) for many search positions, only the first several lower bounds in the list need to be calculated. Our experiments have shown that, when applying to motion vector estimation for several widely-used test videos, 92% to 98% of operations can be saved while still guaranteeing the global optimality. Moreover, the proposed algorithm can be easily modified either to meet the limited time requirement or to provide an ordered list of best candidate matches. Our source codes of the proposed algorithm are available at http://smart.iis.sinica.edu.tw/html/winup.html.

  18. Romanticism or Reality? An Exploration of Frances Mary Hendry's "Chandra."

    Science.gov (United States)

    Johnson, Jilaine

    This paper singles out a novel written for children about India, "Chandra" (1995) by Frances Mary Hendry, as a powerful and useful novel to present to today's 11 to 14 year old students. The paper contends that the novel allows students to explore and consider different value systems, challenges them to become aware of prejudice and the…

  19. Mary E. Hall: Dawn of the Professional School Librarian

    Science.gov (United States)

    Alto, Teresa

    2012-01-01

    A century ago, a woman named Mary E. Hall convinced school leaders of the need for the professional school librarian--a librarian who cultivated a love of reading, academic achievement, and independent learning skills. After graduating from New York City's Pratt Institute Library School in 1895, Hall developed her vision for the high school…

  20. Rosie Carpe and the Virgin Mary: Modelling Modern Motherhood

    Directory of Open Access Journals (Sweden)

    Pauline Eaton

    2016-06-01

    Full Text Available Marie NDiaye’s 2001 novel, Rosie Carpe, incorporates, as one of its several instances of parenting failure, the narrative of the decline of a single mother from adequacy to abuse. This narrative, which is the focus of this article, might be said to put flesh on the bones of Julia Kristeva’s deconstruction of the Virgin Mary in her 1980s essay ‘Stabat Mater’. Kristeva saw the Marian model as out of date but she interrogated its enduring power and its continuing influence on our cultural perceptions of maternity. NDiaye’s eponymous Rosie realises she is pregnant but has no idea how this has come about. Rosie is not represented as a woman who has a religious faith but she decides to accept her child as a holy miracle. This article analyses how the ‘mythology’ of the Virgin Mary, and other biblical intertext, is woven into the narrative of Rosie’s experience of motherhood, so as to counterpoint and illuminate Rosie’s bleak and raw inner experience of maternity, an experience which, while confirming that Rosie is not, and never could have been, a modern Virgin Mary nevertheless refreshes the human stories at the root of the Christian narrative.

  1. 2016-2017 Travel Expense Reports for Mary Anne Chambers ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    chantal taylor

    Purpose: Board meetings. Date(s):. 2017-03-19 to 2017-03-22. Destination(s):. Ottawa. Airfare: $121.05. Other. Transportation: $51.92. Accommodation: $926.48. Meals and. Incidentals: $190.40. Other: $0.00. Total: $1,289.85. Comments: 2016-2017 Travel Expense Reports for Mary. Anne Chambers, Governor ...

  2. 2017-2018 Travel Expense Reports for Mary Anne Chambers ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Chantal Taylor

    Ottawa. Airfare: $563.72. Other. Transportation: $74.26. Accommodation: $0.00. Meals and. Incidentals: $46.17. Other: $30.00. Total: $714.15. Comments: From residence in Thornhill, Ontario. 2017-2018 Travel Expense Reports for Mary. Anne Chambers, Governor, Chairperson of the. Human Resources Committee.

  3. 2016-2017 Travel Expense Reports for Mary Anne Chambers ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Beata Bialic

    Purpose: Board meetings. Date(s):. 2016-11-20 to 2016-11-23. Destination(s):. Ottawa. Airfare: $445.14. Other. Transportation: $29.05. Accommodation: $786.80. Meals and. Incidentals: $76.79. Other: $0.00. Total: $1,337.78. Comments: 2016-2017 Travel Expense Reports for Mary. Anne Chambers, Governor, Chairperson ...

  4. 2016-2017 Travel Expense Reports for Mary Anne Chambers ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Beata Bialic

    Date(s):. 2016-08-14 to 2016-08-23. Destination(s):. Peru/Colombia. Airfare: $3,484.87. Other. Transportation: $0.00. Accommodation: $1,942.21. Meals and. Incidentals: $395.27. Other: $75.50. Total: $5,897.85. Comments: 2016-2017 Travel Expense Reports for Mary. Anne Chambers, Governor, Chairperson of the.

  5. 2017-2018 Travel Expense Reports for Mary Anne Chambers ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Chantal Taylor

    Ottawa. Airfare: $368.41. Other. Transportation: $69.95. Accommodation: $542.79. Meals and. Incidentals: $164.42. Other: $0.00. Total: $1,145.57. Comments: From residence in Thornhill, Ontario. 2017-2018 Travel Expense Reports for Mary. Anne Chambers, Governor, Chairperson of the. Human Resources Committee.

  6. 2016-2017 Travel Expense Reports for Mary Anne Chambers ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Beata Bialic

    Date(s):. 2016-07-06. Destination(s):. Ottawa. Airfare: $482.11. Other. Transportation: $64.30. Accommodation: $0.00. Meals and. Incidentals: $25.28. Other: $0.00. Total: $571.69. Comments: 2016-2017 Travel Expense Reports for Mary. Anne Chambers, Governor, Chairperson of the. Human Resources Committee.

  7. Charcot-Marie-Tooth disease type 1A

    DEFF Research Database (Denmark)

    Hertz, Jens Michael; Børglum, A D; Brandt, C A

    1994-01-01

    Charcot-Marie-Tooth disease type 1A (CMT1A) is an autosomal dominant peripheral neuropathy associated with a DNA duplication on chromosome 17p11.2-p12 in the majority of cases. Most of the sporadic cases are due to a de novo duplication. We have screened for this duplication in 11 Danish patients...

  8. MRI of congenital Foix-Chavany-Marie syndrome

    Energy Technology Data Exchange (ETDEWEB)

    Cellerini, M. [Cattedra di Neuroraliologia, Univ. di Firenze (Italy); Mascalchi, M. [Cattedra di Radiologia, Univ. di Pisa (Italy); Salvi, F. [Div. di Neurologia, Ospedale Bellario, Bologna (Italy); Muscas, G.C. [Dipt. di Scienze Neurologiche e Psichiatriche, Univ. di Firenze (Italy); Dal Pozzo, G. [Cattedra di Neuroraliologia, Univ. di Firenze (Italy)

    1995-06-01

    MRI findings of bilateral central macrogyria allowed the diagnosis of a congenital variant of Foix-Chavany-Marie syndrome in four patients aged between 13 and 32 years, with facio-pharyngo-glosso-masticatory central diplegia, mental retardation and seizures. (orig.)

  9. In Memoriam: Emerita Professor Mary Esther Kropp Dakubu | Osam ...

    African Journals Online (AJOL)

    2016-11-17

    From 2011 to 2016, she was the Editor-In-Chief of the Ghana Journal of Linguistics. She also co-edited the six volume series Studies in the Languages of the Volta Basin published by the Department of Linguistics, University of Ghana. Prof. Mary Esther Kropp Dakubu passed away on November 17, 2016, in Boston, MA, ...

  10. Naine : masin või loom? / Maris Palgi

    Index Scriptorium Estoniae

    Palgi, Maris

    2007-01-01

    Eero Taltsi, Margus Kiisi, Maia Mölleri, Kaie Luige, Eva Orava ja Maris Palgi projektist "Maine-loom, naine-masin", mida tutvustati 2006. a. Moostes üritusel "Postsovkhoz 6", 2007. a. jaanuaris-veebruaris Tartu Kunstimajas ja Tartu Tampere Majas. Näitused avati E. Taltsi ja M. Kiisi loeng-performance'itega

  11. Lift as You Climb: A Profile of President Mary Vosevich

    Science.gov (United States)

    Blumenthal, Anita

    2012-01-01

    "My thumb got me into this!" declares the new APPA President Mary Vosevich when asked how she entered the field of educational facilities management. It was 1984, and Vosevich, a Midwest native, was working at Monsanto in St. Louis as a research biologist, having earned her B.S. in horticulture/agriculture from the University of…

  12. A Day in the Life of Mary Cassatt.

    Science.gov (United States)

    Stoppel, Julie

    2002-01-01

    Offers a way to present art history to classroom students where the art teacher pretends to be an artist. Focuses on a lesson where the teacher pretended to be Mary Cassatt. States that the students used pastels when drawing their artwork, in conjunction with the art history lesson. (CMK)

  13. 2017-2018 Travel Expense Reports for Mary Anne Chambers ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Chantal Taylor

    Purpose: Board Meetings. Date(s):. 2017-11-19 to 2017-11-24. Destination(s):. Ottawa. Airfare: $607.68. Other. Transportation: $107.05. Accommodation: $1,064.06. Meals and. Incidentals: $406.62. Other: $0.00. Total: $2,185.41. Comments: From residence in Thornhill, Ontario. 2017-2018 Travel Expense Reports for Mary.

  14. Marie Stopes International Child Spacing Clinics in Malawi

    African Journals Online (AJOL)

    programme, male involvement has the following basic aspects: Initiation of dialogue on child spacing within the ... that men feel that child spacing is also their concern and service providers feel men are not outsiders. ... pioneering work of Marie Stopes in caring for women in the poor communities of London by extending the ...

  15. From security to attachment : Mary Ainsworth's contribution to attachment theory

    NARCIS (Netherlands)

    Rosmalen, Lenette (Lenny) van

    2015-01-01

    Even though John Bowlby (1907-1990) is generally regarded as the founder of attachment theory, Mary Ainsworth’s (1913-1999) contribution is considerable and goes beyond the design of the Strange Situation Procedure and the introduction of maternal sensitivity as decisive for a secure attachment

  16. 2017-2018 Travel Expense Reports for Mary Anne Chambers ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Chantal Taylor

    Purpose: Represent IDRC at Rideau Hall event. Date(s):. 2017-06-05. Destination(s):. Ottawa. Airfare: $788.71. Other. Transportation: $0.00. Accommodation: $0.00. Meals and. Incidentals: $0.00. Other: $0.00. Total: $788.71. Comments: From residence in Thornhill, Ontario. 2017-2018 Travel Expense Reports for Mary.

  17. Eesti NATO ukselävel / Mari-Ann Kelam

    Index Scriptorium Estoniae

    Kelam, Mari-Ann, 1946-

    2002-01-01

    Seda, et NATO liitumisläbirääkimistele kutsutavate seas on ka Eesti, saab veel tänagi pidada üheks meie iseseisva riikluse suursaavutuseks, kui mitte imeks, kirjutab Riigikogu liige Mari-Ann Kelam. Autor: Isamaaliit. Parlamendisaadik

  18. Reklaamid nagu kino / Jean Marie Bouriscot ; interv.Valner Valme

    Index Scriptorium Estoniae

    Bouriscot, Jean Marie

    2001-01-01

    Sakala keskuses toimus reedel 6. korda reklaamiõgijate öö, kus näidati reklaamiklippe Jean Marie Bouriscotþ kogust. Kogu omanik polnud küll seekord ise kohal, kuid vastas siiski ajakirjaniku küsimustele oma huviala kohta

  19. Molecular Diagnosis of Charcot-Marie Tooth Disease

    Directory of Open Access Journals (Sweden)

    J. Gordon Millichap

    2002-02-01

    Full Text Available The frequency of mutations in certain genes in 153 unrelated patients with Charcot-Marie-Tooth disease (CMT was determined by DNA sequencing before clinical testing at the Departments of Molecular and Human Genetics and Pediatrics, Baylor College of Medicine, Houston, TX, and other centers.

  20. Mother and child. A psychobiographical portrait of Mary Cassatt.

    Science.gov (United States)

    Zerbe, K J

    1987-01-01

    The noted American impressionist, Mary Cassatt is remembered for her intimate portrayal of women, children, and the mother-child relationship. In this paper I have attempted to highlight some of the psychological forces impinging upon the artist, feeling that the artist's work is highly overdetermined. Mention was made of some of the difficulties that a psychobiographical study engenders. Nevertheless, it is hoped that such a study leads to enhanced understanding and appreciation of the artist, her work, and her rich inner world. An examination of the artist's life indicates that difficulties in the family of origin impinged upon her and deeply influenced her work. The loss of several siblings during critical developmental subphases may have produced intense survival guilt in Mary, motivating her to "recreate" her siblings on canvas and to devote her life to care of survivors. Lack of confirmation of Mary's talents by her father may have hindered her development, propelling the child toward a profoundly libidinalized and enmeshed relationship with the mother. Mary's intense relationship with her mother may have led the artist to develop particular stylistic nuances in her productions, contributed to her inability to become a wife and mother herself, and led to frequent episodes of depression. A case was made that Mary suffered from narcissistic disturbance, never completing the recognition of herself as a person outside of the orbit of her mother. Finally, the role of Edgar Degas in the artist's life was described. He seems to have played a major role in the evolution of Mary's style as well as being an important influence in her making a partial separation from her mother in adulthood. In spite of Mary's deep personal suffering, she was able to epitomize in her paintings the most tender and nurturant of relationships. By painting the mother-child theme, she sublimated her own wishes to become a mother as creator of art. Within her family system, she appropriated

  1. Marie Sklodowska-Curie, polonium, radium and radiochemistry; Marie Sklodowska Curie, le polonium, le radium et la radiochimie

    Energy Technology Data Exchange (ETDEWEB)

    Guillaumont, R. [Paris-11 Univ., 91 - Orsay (France)

    2011-05-15

    In this work, the author describes how the methodology developed by Marie Curie in discovering polonium and radium has contributed to greater scientific discoveries and how these discoveries have played a great part in the development of science in general and have particularly enriched chemistry. (O.M.)

  2. Age and sex differences in game-related statistics which discriminate winners from losers in elite basketball games

    Directory of Open Access Journals (Sweden)

    Haruhiko Madarame

    2018-02-01

    Full Text Available Abstract AIMS To advance knowledge of long-term development of basketball players, this study investigated age and sex differences in game-related statistics which discriminate winners from losers in World Basketball Championships held after the 2010 rule change. METHODS A total of 935 games from six categories (under-17, under-19 and open age for both men and women were analyzed. All games were classified into three types (balanced, unbalanced and very unbalanced according to point differential by a k-means cluster analysis. A discriminant analysis was performed to identify game-related statistics which discriminate winners from losers in each game type. An absolute value of a structural coefficient (SC equal to or above 0.30 was considered relevant for the discrimination. RESULTS In balanced games, assists discriminated winners from losers in open games (men, |SC| = 0.32; women, |SC| = 0.34, whereas successful free throws did so in under-17 games (men, |SC| = 0.30; women, |SC| = 0.31. Successful 2-point field goals discriminated winners from losers only in women’s games (under-19, |SC| = 0.38; open, |SC| = 0.36. CONCLUSION There were three novel findings in balanced games: 1 successful free throws but not assists discriminated winners from losers in under-17 games; 2 successful 2-point field goals discriminated winners from losers in women’s games but not in men’s games; and 3 discriminating power of successful 3-point field goals was extremely small in women’s games. These results may be related to the new rules for the shot clock and the 3-point distance.

  3. Mechanisms of Winner-Take-All and Group Selection in Neuronal Spiking Networks.

    Science.gov (United States)

    Chen, Yanqing

    2017-01-01

    A major function of central nervous systems is to discriminate different categories or types of sensory input. Neuronal networks accomplish such tasks by learning different sensory maps at several stages of neural hierarchy, such that different neurons fire selectively to reflect different internal or external patterns and states. The exact mechanisms of such map formation processes in the brain are not completely understood. Here we study the mechanism by which a simple recurrent/reentrant neuronal network accomplish group selection and discrimination to different inputs in order to generate sensory maps. We describe the conditions and mechanism of transition from a rhythmic epileptic state (in which all neurons fire synchronized and indiscriminately to any input) to a winner-take-all state in which only a subset of neurons fire for a specific input. We prove an analytic condition under which a stable bump solution and a winner-take-all state can emerge from the local recurrent excitation-inhibition interactions in a three-layer spiking network with distinct excitatory and inhibitory populations, and demonstrate the importance of surround inhibitory connection topology on the stability of dynamic patterns in spiking neural network.

  4. Technical and physical analysis of the 2014 FIFA World Cup Brazil: winners vs. losers.

    Science.gov (United States)

    Rumpf, Michael C; Silva, Joao R; Hertzog, Maxime; Farooq, Abdulaziz; Nassis, George

    2017-10-01

    The purpose of the present study was to investigate the technical and physical performance parameters that distinguish between teams winning and losing matches in the 2014 FIFA World Cup Brazil. Data were derived from the FIFA website and from live-statistics provided during each game of the world cup. Twelve physical (such as total distance covered in meters (TD), TD in distinct locomotor categories: low-intensity running (LIR; 14 km/h)) and 21 technical parameters (total passes, short-, medium- and long-distance passes, total pass completion rate, dangerous attacks, attacking attempts, delivery in penalty area, ball possession, goals, goals from set-pieces, goals per shot on goal, defending saves, shots, shots on goal, shot accuracy, set-pieces, crosses, corners, clearances, yellow cards) were analyzed. Forty-two games in which a winner and consequently a loser were presented after 90 minutes of game time were investigated with independent t-tests. A binary-logistic regression was utilized to investigate whether the significant variables predicted success of the winning teams. The winning teams scored significantly (PTechnical performance related to goal scoring parameters play a decisive role in World Cup games. Furthermore, scoring efficacy from open-play as well as from set-pieces are crucial to win matches in a World Cup tournament. At this level, physical performance was not the factor to discriminate between winners and losers.

  5. Meet the winner artists of Accelerate@CERN Taiwan | 3 February

    CERN Multimedia

    2016-01-01

    The winners of Accelerate@CERN Taiwan are WenChi Su (left) and Pei-Ying Lin (right). Accelerate@CERN is the country-specific, one-month research award for artists who have never been in a science laboratory before. Accelerate@CERN Taiwan, is funded by the Ministry of Culture for Taiwan. From within thirty outstanding applicants, the winners of Accelerate@CERN Taiwan are WenChi Su - dancer and choreographer - and Pei-Ying Lin - digital artist. This is the first opportunity for two talented artists to work and research together on the joint creation of a new dance project which engages with the digital realm and is inspired by the world of particle physics. In the past month they have been exploring CERN together, and now they are working on their project. Meet the artists on Wednesday 3 February at 4:30 p.m. in Restaurant 1. For more information on Accelerate@CERN, see here. Follow the artists blog to know what they have been doing for the past month at CERN.

  6. Winners and losers: analysing post-disaster spatial economic demand shift.

    Science.gov (United States)

    Xiao, Yu; Nilawar, Uttara

    2013-10-01

    Disasters produce winners and losers. This paper evaluates such winners and losers in a spatial context. The hypothesis is that, because of severe damage to the core disaster area and the constraints associated with the cost of transportation, economic demand would shift to the immediate edge of the disaster zone where either minor or no damage is observed. Empirical analysis of growth patterns in counties/parishes in the states of Alabama, Louisiana, and Mississippi in the United States after Hurricane Katrina (August 2005) verified the spatial demand shift hypothesis. The study found that the post-Katrina core disaster area became a 'doughnut hole' of low income and employment growth, surrounded by a ring of high growth counties/parishes on the edge of the hole. The short-run adjustment in growth rates may have altered permanently the spatial distribution of employment and income both at the core and in the areas at the edge. © 2013 The Author(s). Disasters © Overseas Development Institute, 2013.

  7. A reversal of fortunes: climate change 'winners' and 'losers' in Antarctic Peninsula penguins.

    Science.gov (United States)

    Clucas, Gemma V; Dunn, Michael J; Dyke, Gareth; Emslie, Steven D; Naveen, Ron; Polito, Michael J; Pybus, Oliver G; Rogers, Alex D; Hart, Tom

    2014-06-12

    Climate change is a major threat to global biodiversity. Antarctic ecosystems are no exception. Investigating past species responses to climatic events can distinguish natural from anthropogenic impacts. Climate change produces 'winners', species that benefit from these events and 'losers', species that decline or become extinct. Using molecular techniques, we assess the demographic history and population structure of Pygoscelis penguins in the Scotia Arc related to climate warming after the Last Glacial Maximum (LGM). All three pygoscelid penguins responded positively to post-LGM warming by expanding from glacial refugia, with those breeding at higher latitudes expanding most. Northern (Pygoscelis papua papua) and Southern (Pygoscelis papua ellsworthii) gentoo sub-species likely diverged during the LGM. Comparing historical responses with the literature on current trends, we see Southern gentoo penguins are responding to current warming as they did during post-LGM warming, expanding their range southwards. Conversely, Adélie and chinstrap penguins are experiencing a 'reversal of fortunes' as they are now declining in the Antarctic Peninsula, the opposite of their response to post-LGM warming. This suggests current climate warming has decoupled historic population responses in the Antarctic Peninsula, favoring generalist gentoo penguins as climate change 'winners', while Adélie and chinstrap penguins have become climate change 'losers'.

  8. THE SEMANTICS OF BIRD DENOMINATIONS IN THE MARI LANGUAGE

    Directory of Open Access Journals (Sweden)

    Kristina Yuzieva

    2012-01-01

    Full Text Available This paper presents an analysis of the semantics of bird denominations in Mari: an attempt is made to define the factors, or features, motivating bird denominations. Analysis is based on a set of words of inner origin that are part of the corpus of bird names compiled by the author. The results show that the ornithonomy of the Mari language, created over centuries, constitutes a well-shaped system. It reflects a variety of features associated with the appearance, way of life of the birds, sounds they produce, etc. Many bird terms reflect features of appearance. It is interesting to note that the names of birds not seen for some reason may relate to the characteristics of the birds’ voices. In some cases, terms are based on a combination of features.In dialects, different names for same birds may occur, as observed in the sources.

  9. Novel Cytotoxic Phenanthrenequinone from Odontioda Marie Noel ‘Velano’

    OpenAIRE

    増田, 裕子; 鈴木, 龍一郎; 坂上, 宏; Umemura, Naoki; 白瀧, 義明

    2012-01-01

    A new phenanthrenequinone, 5-hydroxy-2,3-dimethoxy-1,4-phenanthrenequinone (1), was isolated along with a known 9,10-dihydrophenanthrenequinone, ephemeranthoquinone B (2) from an MeOH extract of Odontioda Marie Noel ‘Velano’ through bioassay-guided fractionation. Their structures were elucidated by spectroscopic analysis, and the compounds were tested for in vitro cytotoxic activity. The compounds showed slightly higher cytotoxicity in human oral squamous cell carcinoma and leukemic cell line...

  10. Restaging Hysteria: Mary Wigman as Writer and Dancer

    OpenAIRE

    Laura A. McLary

    2003-01-01

    Mary Wigman was not only a leading proponent of the early twentieth-century Expressionist dance movement, but also a writer of poetry and short poetic prose. Despite her assertion that dance was beyond language, she wrote often about dance in an attempt to articulate the kinesthetic experience of dance through languages. This interdisciplinary study explores the intersection of dance and writing for Wigman, focusing on gender coding in writing and dance within the context of early twentieth-c...

  11. From security to attachment: Mary Ainsworth's contribution to attachment theory

    OpenAIRE

    Rosmalen, Lenette (Lenny) van

    2015-01-01

    Even though John Bowlby (1907-1990) is generally regarded as the founder of attachment theory, Mary Ainsworth’s (1913-1999) contribution is considerable and goes beyond the design of the Strange Situation Procedure and the introduction of maternal sensitivity as decisive for a secure attachment relationship. Ainsworth worked in Toronto with William Blatz (1895-1964) for almost two decades before she moved to London and worked with Bowlby in 1950. Ainsworth was heavily influenced by Blatz and ...

  12. Baltika kvartal = Baltika Quarter / Maris Kerge, Kadri Kerge

    Index Scriptorium Estoniae

    Kerge, Maris

    2010-01-01

    Rekonstrueeritud Baltika tööstushoonest: Moetänavast ja AS Baltika büroodest. Projekteerija, sisearhitektuur büroode osas: Studio 3 (4 arhitekti), büroo Kolm Pluss Üks (9 arhitekti). Sisearhitektuur Moetänava osas: Pekka Porkanen, Maris Kerge, Ott Kangur, Maire Milder, Lembit-Kaur Stöör, Ülo-Tarmo Stöör, Lauri Eltermaa, Pärtel Eelma. Projekt: 2007-2009, valmis: 2009

  13. Revisiting Mary Daly: Towards a quadripartite theological and philosophical paradigm

    Directory of Open Access Journals (Sweden)

    Hannelie Wood

    2015-06-01

    Full Text Available I was a tenderfoot in feminist discourse when I started my research on patriarchy, feminism, and Mary Daly. In my thesis, one aspect I engaged was Daly’s battle with gender issues in Christian theology. From the beginning I was troubled by Mary Daly’s views on God, men, and women in her discourse on Christianity. Daly undoubtedly contributed to the discussion on gender issues in the Christian faith, but her focus on androcentrism and her interpretations of Scripture led her to abandon the Christian faith. Mary Daly has written extensively on patriarchy as it is found in religion – particularly in the Christian faith – and how it filters through society. In her critique of patriarchy she set her course to dismantle the facade of a patriarchal and misogynistic God as the root of patriarchy. Daly did not see any positive qualities of the Christian faith and completely rejected other interpretations of a God whose person embraces both male and female qualities. Against this background I will evaluate Daly’s post-Christian feminist theological and philosophical paradigm. I propose that Daly has a quadripartite theological and philosophical paradigm wherein there are four main players. The ‘Who is who’ in Daly’s quadripartite patriarchal theological and philosophical paradigm are the patriarchal male, the patriarchal female, the patriarchal God and the biophilic woman.

  14. A different voice: Mary Hays's the Memoirs of Emma Courtney.

    Science.gov (United States)

    Sharma, A

    2001-01-01

    Mary Hays wrote in the decade of the 1790s, a period of intense creative flowering in England. Writing in a period enshrined to the works of the canonical Wordsworth and Coleridge, Hays explored through her Jacobinical novel, The Memoirs of Emma Courtney, the contentious relationship between self and society. Like other Jacobin women writers - Elizabeth Inchbald, Charlotte Smith and Mary Wollstonecraft - Mary Hays too used her novel to explode the insidious connection between education and gender construction. Emma Courtney is a landmark novel that wrestles with the paradigm of decorum and propriety which disallows women from voicing their aspirations. In the process, Hays merges the plots of the domestic novel of courtship and love with the novel of ideas to create a searing portrait of women's intellectual confinement and psychic dissonance in a society that only projects them in terms of their gender construction. Memoirs of Emma Courtney is a remarkable novel in its depiction of the emotional imbalance created by thwarted desire: intellectual and sexual.

  15. The Pasteurization of Marie Curie: A (meta)biographical experiment.

    Science.gov (United States)

    Wirtén, Eva Hemmungs

    2015-08-01

    Biographies of scientists occupy a liminal space, highly popular with general readers but questioned in academia. Nonetheless, in recent years, historians of science have not only embraced the genre with more enthusiasm and less guilt, they have also turned to the metabiography in order to renew the study and story of scientists' roles. This essay focuses on Marie Curie, the world's most famous female scientist, in order to unpack some of the theoretical and methodological claims of the science biography, and especially to address the sexing mechanisms at play in the construction of the biographical subject. Pierre Curie (1923), Marie's biography of her husband Pierre, paid tribute to her dead husband and collaborator, but also allowed Curie a legitimate outlet to construct her own persona and legacy. Categories such as personhood, person, and persona are not only central to the biography genre but also are essential to the sense of self and self-fashioning of scientists. Looking at how Marie Curie negotiated these categories in Pierre Curie not only gives new insight into Curie's self-fashioning strategies but may also shed some light on the more general analytical lacunae of the science biography.

  16. Trans-Colonial Collaboration and Slave Narrative: Mary Prince Revisited

    Directory of Open Access Journals (Sweden)

    Michelle Gadpaille

    2011-10-01

    Full Text Available In 1831 in London, two formidable women met: Mary Prince, an ex-slave from Bermuda, who had crossed the Atlantic to a qualified freedom, and Susanna Strickland, an English writer. The narrative that emerged from this meeting was The History of Mary Prince, which played a role in the fight for slave emancipation in the British Empire. Prince disappeared once the battle was won, while Strickland emigrated to Upper Canada and, as Susanna Moodie, became an often quoted 19th century Canadian writer. Prince dictated, Strickland copied, and the whole was lightly edited by Thomas Pringle, the anti-slavery publisher at whose house the meeting took place. This is the standard account. In contesting this version, the paper aims to reinstate Moodie as co-creator of the collaborative Mary Prince text by considering multiple accounts of the meeting with Prince and to place the work in the context of Moodie’s pre- and post-emigration oeuvre on both sides of the Atlantic.

  17. Can We Tell Winners and Losers Apart? : Social and Cultural Effects on Facial Expressions of Children and Adults in Games

    NARCIS (Netherlands)

    Mui, Hoi Ching; Goudbeek, Martijn; Swerts, Marc; Freitas-magalhães, A

    2015-01-01

    Can we tell winners and losers apart, on the basis of their facial expressions? In this chapter, we investigate the effects of social and cultural factors on expressions associated with winning and losing in games. Eight-year-olds and adults, who were either Dutch or Chinese, played games alone or

  18. An Evaluation of the Trends of Realism in Caldecott Winner and First Honor Books 1966-1986.

    Science.gov (United States)

    Smith, John A., Jr.; Napier, Georgia

    To determine if there were any consistent tendencies toward the abstract or toward impressionism in the illustration of children's books between the years 1966 and 1986, a study examined the illustrations of Caldecott winners and Honor books. The study replicated John Stewig's study (using his evaluation instrument) of the same topic which covered…

  19. Measuring Excellence: A Closer Look at Malcolm Baldrige National Quality Award Winners in the Manufacturing Category

    Directory of Open Access Journals (Sweden)

    Brian Cazzell

    2009-05-01

    Full Text Available The Malcolm Baldrige National Quality Award is the nation’s highest quality award. The application and review process is outlined in this work. The objective of this study was to examine the five previous winners in the Manufacturing category and to establish a firm conclusion about the award’s impact. The impact of the award was examined in several categories including financial performance, market share, and employee productivity. This study explored the accomplishments of each company and compared the common factors they shared with one another. It was found that all five companies experienced tremendous financial growth on average of 100% in either sales or revenue as a result of their dedication to quality which ultimately led to winning the MBNQA.

  20. GRASP with Hybrid Path Relinking for Bi-Objective Winner Determination in Combinatorial Transportation Auctions

    Directory of Open Access Journals (Sweden)

    Tobias Buer

    2010-10-01

    Full Text Available The procurement of transportation services via large-scale combinatorial auctions involves a couple of complex decisions whose outcome highly influences the performance of the tender process. This paper examines the shipper's task of selecting a subset of the submitted bids which efficiently trades off total procurement cost against expected carrier performance. To solve this bi-objective winner determination problem, we propose a Pareto-based greedy randomized adaptive search procedure (GRASP. As a post-optimizer we use a path relinking procedure which is hybridized with branch-and-bound. Several variants of this algorithm are evaluated by means of artificial test instances which comply with important real-world characteristics. The two best variants prove superior to a previously published Pareto-based evolutionary algorithm.

  1. Using transactional analysis to improve clinical and educational supervision: the Drama and Winner's triangles.

    Science.gov (United States)

    McKimm, Judy; Forrest, Kirsty

    2010-05-01

    The supervisor-trainee relationship is fundamental in ensuring the best continuing education for all trainees. One of the key skills of supervision is being able to communicate effectively; however, this is sometimes difficult. In this article we explore how two transactional analysis models, the Drama and Winner's triangles, can help supervisors work and communicate more effectively with trainees. All supervisors will have had a 'heartsink moment' before meeting a known trainee. The models can be used to explain these situations and what exactly is happening to the communication. The models provide methods of breaking free from these frustrating encounters and moving on with the relationship with your trainee. The models also help us understand the ways in which we can easily be pulled into games and offer insight into our own behaviours and relationships, not only with trainees, but also with patients, carers and colleagues. Real life scenarios are used throughout to explain the models.

  2. Self-deception's adaptive value: effects of positive thinking and the winner effect.

    Science.gov (United States)

    Lopez, Jason Kido; Fuxjager, Matthew J

    2012-03-01

    There is a puzzle about why self-deception, a process that obscures the truth, is so pervasive in human behavior given that tracking the truth seems important for our survival and reproduction. William von Hippel and Robert Trivers argue that, despite appearances, there is good reason to think that self-deception is an adaptation by arguing: (1) self-deception leads to a positive self-perception and (2) a positive self-perception increases an individual's fitness. D.S. Neil Van Leeuwen, however, gives persuasive arguments against both steps. In response, we will defend both propositions, thereby supporting the conclusion that self-deception indeed has adaptive value. The first premise will be bolstered by a survey of the philosophical literature and empirical work on self-deception, whereas the second will be strengthened by empirical research on a behavioral phenomenon known as the winner effect. Copyright © 2011 Elsevier Inc. All rights reserved.

  3. Quality in the 21st century perspectives from ASQ Feigenbaum medal winners

    CERN Document Server

    Saraiva, Pedro

    2016-01-01

    This book is a compilation of perspectives provided by several winners of the ASQ Feigenbaum Medal, which is awarded each year to an individual under the age of 35 who has made a significant contribution to the field of Quality. As such, it serves as a valuable reference book in this area. It is primarily based on the medalists’ vision to "refresh" and "re-think" the quality concepts that have been used over the past century and the future development of the topic. Maximizing readers’ understanding of the ways in which Quality is created, it provides insights from pioneers in this field from around the globe and anticipates how and what Quality will be in the future, as well as how people and organizations can benefit from it today.

  4. The Stock Performance of C. Everett Koop Award Winners Compared With the Standard & Poor's 500 Index

    Science.gov (United States)

    Goetzel, Ron Z.; Fabius, Raymond; Fabius, Dan; Roemer, Enid C.; Thornton, Nicole; Kelly, Rebecca K.; Pelletier, Kenneth R.

    2016-01-01

    Objective: To explore the link between companies investing in the health and well-being programs of their employees and stock market performance. Methods: Stock performance of C. Everett Koop National Health Award winners (n = 26) was measured over time and compared with the average performance of companies comprising the Standard and Poor's (S&P) 500 Index. Results: The Koop Award portfolio outperformed the S&P 500 Index. In the 14-year period tracked (2000–2014), Koop Award winners’ stock values appreciated by 325% compared with the market average appreciation of 105%. Conclusions: This study supports prior and ongoing research demonstrating a higher market valuation—an affirmation of business success by Wall Street investors—of socially responsible companies that invest in the health and well-being of their workers when compared with other publicly traded firms. PMID:26716843

  5. An Analysis of the Symptomatic Domains Most Relevant to Charcot Marie Tooth Neuropathy (CMT) Patients

    Science.gov (United States)

    2017-06-09

    Charcot Marie Tooth Disease (CMT); Hereditary Sensory and Motor Neuropathy; Nerve Compression Syndromes; Tooth Diseases; Congenital Abnormalities; Genetic Diseases, Inborn; Heredodegenerative Disorders, Nervous System

  6. Novel cytotoxic phenanthrenequinone from Odontioda Marie Noel 'Velano'.

    Science.gov (United States)

    Masuda, Yuko; Suzuki, Ryuichiro; Sakagami, Hiroshi; Umemura, Naoki; Shirataki, Yoshiaki

    2012-01-01

    A new phenanthrenequinone, 5-hydroxy-2,3-dimethoxy-1,4-phenanthrenequinone (1), was isolated along with a known 9,10-dihydrophenanthrenequinone, ephemeranthoquinone B (2) from an MeOH extract of Odontioda Marie Noel 'Velano' through bioassay-guided fractionation. Their structures were elucidated by spectroscopic analysis, and the compounds were tested for in vitro cytotoxic activity. The compounds showed slightly higher cytotoxicity in human oral squamous cell carcinoma and leukemic cell lines as compared with human oral normal cells. The results suggest that apoptosis may not be involved in the cytotoxicity induction.

  7. Making space for Wollstonecraft: Mary Barker's A Welsh Story

    OpenAIRE

    Chadwick, Mary

    2017-01-01

    As Jane Aaron observes, as a setting for novels of sensibility and domestic fiction, Wales ‘could prove attractive to the Romantic radical, disillusioned by the restrictions and artifice of contemporary English culture.’ This certainly appears to be true of Mary Barker (1774–1853) who published the almost forgotten A Welsh Story in 1798. As its title suggests, Barker’s text is an example of ‘Wales-related fiction’, Andrew Davies’s umbrella term for the fashionable Romantic novels which set so...

  8. Uus kuum Eesti disain / Silvia Pärmann, Maris Takk

    Index Scriptorium Estoniae

    Pärmann, Silvia

    2015-01-01

    Karl Tauli disainitud taburet "Ämblu", Aap Piho puidust ümmargune laud, Marit Ilisoni tekkmantlid kollektsioonist "Longing for Sleep/Magada tahaks", Narma vaibakollektsioon "OPEN 2015/16" (disainerid Monika Järg, Kaidi Ploomipuu), Annike Laigo vaibakollektsioon "XX", Kairi Katmanni vaip "Storytellers", Valhalla Factory kollektsiooni "Daydreamers" ripptool, Raili Keivi betoonist ja portselanist nõudekollektsioon, Tarmo Luisu valgusti "Kassett", Stella Soomlaisi käekotid, Karin Kallase ja Erik Pasti (Stuudio Nahk) disainitud jalatsid, käekotid ja ehted, Kuula + Jylhä jalatsikollektsioon, Mokoko (disainer Mari Maripuu) nahast aksessuaarid

  9. The ascent of Mary Somerville in 19th century society

    CERN Document Server

    Strickland, Elisabetta

    2016-01-01

    This biography traces the life and work of Mary Fairfax Somerville, whose extraordinary mathematical talent only came to light through fortuitous circumstances. Barely taught to read and write as a child, all the science she learned and mastered was self taught. In this delightful narrative the author takes up the challenge of discovering how Somerville came to be one of the most outstanding British women scientists and, furthermore, a popular writer. Particular attention is paid to the gender aspects of Somerville's success in what was, to put it mildly, a predominantly male domain.

  10. Leaching and solvent extraction at Mary Kathleen Uranium Ltd

    International Nuclear Information System (INIS)

    Richmond, G.D.

    1978-01-01

    Mary Kathleen Uranium Ltd. recommenced operations in early 1976 following a twelve year period of care and maintenance. Several sections of the plant were modified or completely changed for the second operation. The most important change was the replacement of ion exchange with solvent extraction as the means of purifying and upgrading uranium rich solutions. Most of the problems experienced in the solvent extraction system originate from the leach liquor which has a strong tendency to form stable emulsions. This has been countered by some careful control of leaching conditions and by closer observation of operations in the solvent extraction area. Most problems have now been resolved and plant recoveries are quite satisfactory

  11. Remembering Joan (Jan) Mary Anderson (1932-2015).

    Science.gov (United States)

    Chow, Wah Soon; Horton, Peter; Barrett, Martin; Osmond, Charles Barry

    2016-08-01

    Joan Mary Anderson, known to most people as Jan, was born on May 12, 1932 in Dunedin, New Zealand. She died on August 28, 2015 in Canberra, Australia. To celebrate her life, we present here a brief biography, some comments on her discoveries in photosynthesis during a career spanning more than half a century, and reminiscences from family and friends. We remember this wonderful person who had an unflagging curiosity, creative ability to think laterally, enthusiasm, passion, generosity and love of color and culture.

  12. Humble Courage:Kierkegaard on Abraham and Mary

    OpenAIRE

    Carlisle, Clare Louise

    2016-01-01

    This article presents a new interpretation of Kierkegaard’s Fear and Trembling that focuses on the comparison between Abraham and Mary in this text. The readings of Genesis 22 and Luke 1 offered by Kierkegaard’s pseudonym Johannes de silentio develop a poetic reconstruction of the biblical characters by imagining their inwardness. In both cases, the inwardness of faith is depicted as ‘humble courage’, a virtue that involves silence and listening. The article argues that it is this virtue, and...

  13. Charcot-Marie-Tooth disease complicating type 2 diabetes.

    LENUS (Irish Health Repository)

    Win, Htet Htet Ne

    2012-02-01

    Although both conditions are relatively common, there are very few descriptions of type 2 diabetes mellitus coexisting with Charcot-Marie-Tooth disease (CMT). This case report and literature review describes a 53-year-old Irish man who presented with type 2 diabetes and significant neuropathy, and who was subsequently diagnosed with CMT type 1A. This case report will also discuss how to differentiate diabetic neuropathy from a progressive hereditary neuropathy and how coexistence aggravates the progression of neuropathy thus necessitating early diagnosis.

  14. Charcot-marie-tooth disease complicating type 2 diabetes.

    LENUS (Irish Health Repository)

    Win, Htet Htet Ne

    2011-07-01

    Although both conditions are relatively common, there are very few descriptions of type 2 diabetes mellitus coexisting with Charcot-Marie-Tooth disease (CMT). This case report and literature review describes a 53-year-old Irish man who presented with type 2 diabetes and significant neuropathy, and who was subsequently diagnosed with CMT type 1A. This case report will also discuss how to differentiate diabetic neuropathy from a progressive hereditary neuropathy and how coexistence aggravates the progression of neuropathy thus necessitating early diagnosis.

  15. Mary Anne Chambers | CRDI - Centre de recherches pour le ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Ancienne députée à l'Assemblée législative de l'Ontario, Mary Anne a été ministre de la Formation, des Collèges et des Universités ainsi que ministre des Services à l'enfance et à la jeunesse au gouvernement de l'Ontario. Elle a en outre occupé le poste de vice-présidente principale à la Banque Scotia. Diplômée de ...

  16. The contribution of women to radiobiology: Marie Curie and beyond☆

    OpenAIRE

    Gasinska, Anna

    2015-01-01

    Marie Sklodowska-Curie, an extraordinary woman, a Polish scientist who lived and worked in France, led to the development of nuclear energy and the treatment of cancer. She was the laureate of two Nobel Prizes, the first woman in Europe who obtained the degree of Doctor of Science and opened the way for women to enter fields which had been previously reserved for men only. As a result of her determination and her love of freedom, she has become an icon for many female scientists active in rad...

  17. The medical applications of the discoveries of Marie Sklodowska-Curie; Les applications medicales des decouvertes de Marie Sklodowska-Curie

    Energy Technology Data Exchange (ETDEWEB)

    Krawczyk, M. [Universite de medecine de Varsovie (Poland)

    2011-05-15

    In this work, the author indicates what have been the applications of the discoveries of Marie Curie in the field of medicine and how these discoveries have contributed in particular to the development of oncologic radiotherapy. (O.M.)

  18. Phenotypic spectrum of dynamin 2 mutations in Charcot-Marie-Tooth neuropathy

    NARCIS (Netherlands)

    Claeys, Kristl G.; Züchner, Stephan; Kennerson, Marina; Berciano, José; Garcia, Antonio; Verhoeven, Kristien; Storey, Elsdon; Merory, John R.; Bienfait, Henriette M. E.; Lammens, Martin; Nelis, Eva; Baets, Jonathan; de Vriendt, Els; Berneman, Zwi N.; de Veuster, Ilse; Vance, Jefferey M.; Nicholson, Garth; Timmerman, Vincent; de Jonghe, Peter

    2009-01-01

    Dominant intermediate Charcot-Marie-Tooth neuropathy type B is caused by mutations in dynamin 2. We studied the clinical, haematological, electrophysiological and sural nerve biopsy findings in 34 patients belonging to six unrelated dominant intermediate Charcot-Marie-Tooth neuropathy type B

  19. Special Workshop of Marie Curie Fellows on Research and Training in Physics and Technology

    CERN Multimedia

    Patrice Loiez

    2002-01-01

    Photo 0210006_07a: Prof. L. Maiani, Director General of CERN. Addressing the Marie Curie Worshop held at CERN 3-4 October 2002. Title of this talk:"Function of Large-scale Facilities and Centres of Excellence". Photo 0210006_14a: Prof. L. Maiani, Director General of CERN. Addressing the Marie Curie Worshop held at CERN 3-4 October 2002. Title of this talk:"Function of Large-scale Facilities and Centres of Excellence". Photo 0210006_22: Dr. David Plane (CERN) introducing Dr. Theodore Papazoglou from the European Commission. Addressing the Marie Curie Worshop held at CERN 3-4 October 2002. Title of this talk:"Marie Curie Fellowships in the 6th Framework Programme". Photo 0210006_28a: Dr. Nora Brambilla, Vice-President of Marie Curie Fellow Association, INFN and Dept. of Physics, University of Milan. Addressing the Marie-Curie Worshop held at CERN 3-4 October 2002. Title of this talk:"Marie Curie Fellows Association". Photo 0210006_29a: Dr. Nora Brambilla, Vice-President of Marie Curie Fellow Association, INFN a...

  20. Using the "Mary Tyler Moore Show" as a Feminist Teaching Tool

    Science.gov (United States)

    Jule, Allyson

    2010-01-01

    This paper explores the use of "The Mary Tyler Moore Show" as a teaching tool used with a group of final-year undergraduate students who gathered together last academic year (2007-8) to explore Women in Leadership, as part of a Communications course. The research focus was: How can the use of "The Mary Tyler Moore Show" (a…

  1. Mari Kurismaa : "Kodu kujundamine vajab isiklikku põhjust" / Gitte Hint

    Index Scriptorium Estoniae

    Hint, Gitte

    2004-01-01

    Mari Kurismaa (sünd. 1956) värvide valikust, kodu kujundamisest, praegusest arhitektuurist ja sisearhitektuurist. Mari Kurismaast, autasud (2002. a. Mies van der Rohe preemia EALi-poolne nominent Jaak Huimerinna ja Indrek Saareperaga Järve Selveri projekti töögrupis). Ill.: neli värv. portreed M. Kurismaast

  2. ‘Het witte spook van Mesdag’. De bruid van Matthijs Maris opnieuw bezien’

    NARCIS (Netherlands)

    Bionda, R.W.A.

    2013-01-01

    The Bride (1867-'68) by Matthijs Maris in The Mesdag Collection is without doubt one of his most intriguing early works. Though he defensively described it as only a 'sketch' which he could not bring to a satisfying end, Maris considered this fairly large piece as quite important. Regardless of its

  3. Phenotypic spectrum of dynamin 2 mutations in Charcot-Marie-Tooth neuropathy.

    NARCIS (Netherlands)

    Claeys, K.G.; Zuchner, S.; Kennerson, M.; Berciano, J.; Garcia, A.; Verhoeven, K.; Storey, E.; Merory, J.R.; Bienfait, H.M.; Lammens, M.M.Y.; Nelis, E.; Baets, J.; Vriendt, E. De; Berneman, Z.N.; Veuster, I. De; Vance, J.M.; Nicholson, G.; Timmerman, V.; Jonghe, P. de

    2009-01-01

    Dominant intermediate Charcot-Marie-Tooth neuropathy type B is caused by mutations in dynamin 2. We studied the clinical, haematological, electrophysiological and sural nerve biopsy findings in 34 patients belonging to six unrelated dominant intermediate Charcot-Marie-Tooth neuropathy type B

  4. Quality-of-life in Charcot-Marie-Tooth disease: the patient's perspective.

    Science.gov (United States)

    Johnson, Nicholas E; Heatwole, Chad R; Dilek, Nuran; Sowden, Janet; Kirk, Callyn A; Shereff, Denise; Shy, Michael E; Herrmann, David N

    2014-11-01

    This study determines the impact of symptoms associated with Charcot-Marie-Tooth disease on quality-of-life. Charcot-Marie-Tooth patients in the Inherited Neuropathies Consortium Rare Diseases Clinical Research Network Contact Registry were surveyed. The survey inquired about 214 symptoms and 20 themes previously identified as important to Charcot-Marie-Tooth patients through patient interviews. Symptom population impact was calculated as the prevalence multiplied by the relative importance of each symptom identified. Prevalence and symptom impact were analyzed by age, symptom duration, gender, Charcot-Marie-Tooth type, and employment status. 407 participants returned the survey, identifying foot and ankle weakness (99.7%) and impaired balance (98.6%) as the most prevalent themes. Foot and ankle weakness and limitations with mobility were the themes with the highest impact. Both symptom prevalence and impact gradually increased with age and symptom duration. Several themes were more prevalent in women with Charcot-Marie-Tooth, including activity limitations, pain, fatigue, hip-thigh weakness, and gastrointestinal issues. All of the themes, except emotional or body image issues, were more prevalent among unemployed individuals. There were minimal differences in symptom prevalence between Charcot-Marie-Tooth types. There are multiple symptoms that impact Charcot-Marie-Tooth quality-of-life in adults. These symptoms have different levels of importance, are readily recognized by patients, and represent critical areas of Charcot-Marie-Tooth health. Copyright © 2014 Elsevier B.V. All rights reserved.

  5. 33 CFR 207.441 - St. Marys Falls Canal and Locks, Mich.; security.

    Science.gov (United States)

    2010-07-01

    ... embarking or debarking from vessels while transiting the locks: (1) The master or mate and not more than... company officials will be permitted to embark at the locks if they are in possession of a letter addressed to the Area Engineer, St. Marys Falls Canal, Sault Ste. Marie, Michigan, from the vessel's master...

  6. The thrill of victory and the agony of defeat: spontaneous expressions of medal winners of the 2004 Athens Olympic Games.

    Science.gov (United States)

    Matsumoto, David; Willingham, Bob

    2006-09-01

    Facial behaviors of medal winners of the judo competition at the 2004 Athens Olympic Games were coded with P. Ekman and W. V. Friesen's (1978) Facial Affect Coding System (FACS) and interpreted using their Emotion FACS dictionary. Winners' spontaneous expressions were captured immediately when they completed medal matches, when they received their medal from a dignitary, and when they posed on the podium. The 84 athletes who contributed expressions came from 35 countries. The findings strongly supported the notion that expressions occur in relation to emotionally evocative contexts in people of all cultures, that these expressions correspond to the facial expressions of emotion considered to be universal, that expressions provide information that can reliably differentiate the antecedent situations that produced them, and that expressions that occur without inhibition are different than those that occur in social and interactive settings. ((c) 2006 APA, all rights reserved).

  7. Lad mig kildre dit subjektiveringspunkt!

    DEFF Research Database (Denmark)

    Krejsler, John B.

    2014-01-01

    John Benedicto Krejsler byder på en alternativ vinkel på den professionelle kærlighed. Han har fokus på forandringen i lærerpraksis som følge af de lærendes mange muligheder for at shoppe rundt mellem læringstilbud, der frister med at opfylde deres selvprojekter. Han beskriver, hvorledes den prof...

  8. Local Area Defense (LAD) Demonstration

    Science.gov (United States)

    2004-09-01

    very personal threat. In the insurance industry, there is a different perspective to the hotel industry . If I were in Calvert County, Maryland, it would...industry, I would go to the caucus gathering places such as the hotel industry , Hospitality Association for hotels, (slide) Capabilities of the private

  9. Marie Curie nurses: enabling patients with cancer to die at home.

    Science.gov (United States)

    Higginson, Irene J; Wilkinson, Susie

    2002-05-01

    Marie Curie Cancer Care established its nursing service in 1958; however, the service has had little formal evaluation. This study aimed to describe and evaluate the care provided by Marie Curie nurse, and in particular to determine whether patients in their care remained and died at home. Two existing data sets were used: data on all patients referred to the Marie Curie Nursing Services in 147 areas of England, Wales, Scotland and Northern Ireland for 26 months, and data on cancer death registrations in England. A request for a Marie Curie nurse was made for 26,632 patients, 97% of whom had cancer and 11% of whom lived alone. The amount of care provided varied enormously (Marie Curie nurses facilitated home death for many patients. Services need to ensure that mechanisms are in place to achieve data collection. Rigorous prospective evaluation is needed in the future.

  10. Winners, losers, and posers: The effect of power poses on testosterone and risk-taking following competition.

    Science.gov (United States)

    Smith, Kristopher M; Apicella, Coren L

    2017-06-01

    A contribution to a special issue on Hormones and Human Competition. The effect of postural power displays (i.e. power poses) on hormone levels and decision-making has recently been challenged. While Carney et al. (2010) found that holding brief postural displays of power leads to increased testosterone, decreased cortisol and greater economic risk taking, this failed to replicate in a recent high-powered study (Ranehill et al. 2015). It has been put forward that subtle differences in social context may account for the differences in results. Power displays naturally occur within the context of competitions, as do changes in hormones, and researchers have yet to examine the effects of poses within this ecologically relevant context. Using a large sample of 247 male participants, natural winners and losers of a physical competition were randomly assigned to hold a low, neutral or high-power postural display. We found no main effect of pose type on testosterone, cortisol, risk or feelings of power. Winners assigned to a high-power pose had a relative, albeit small, rise in testosterone compared to winners who held neutral or low-power poses. For losers, we found little evidence that high-power poses lead to increased testosterone relative to those holding neutral or low-powered poses. If anything, the reverse was observed - losers had a reduction in testosterone after holding high-power poses. To the extent that changes in testosterone modulate social behaviors adaptively, it is possible that the relative reduction in testosterone observed in losers taking high-powered poses is designed to inhibit further "winner-like" behavior that could result in continued defeat and harm. Still, effects were small, multiple comparisons were made, and the results ran counter to our predictions. We thus treat these conclusions as preliminary. Copyright © 2016 Elsevier Inc. All rights reserved.

  11. Angles of Refraction: The Letters of Mary Delany

    Directory of Open Access Journals (Sweden)

    Eleonora Chiavetta

    2014-04-01

    Full Text Available Mary Delany (1700-1788 is particularly famous for her paper-cuttings or ‘mosaicks’ based on botanical subjects. A very lively woman of fashion, she was close to Queen Charlotte and one of the Bluestocking Ladies. She left a vivid portrait of life and society in eighteenth century England and Ireland in the six volumes of her Autobiography and Letters, edited in 1861 by her descendant Lady Llanover. Her autobiography is made up of 18 letters sent to her most intimate friend, Margaret Cavendish, Duchess of Portland. The first letter is dated 1740, but in this, as in the following ones, Mrs. Delany narrates her past life to her friend, starting from the early years of her life, describing her unhappy marriage, financial difficulties as a widow, and family relationships. Along with these ‘autobiographical’ letters, other letters written by her to her sister Ann are introduced, which date to the periods of life Mrs. Delany is dealing with. The aim of this paper is to focus on the textual, linguistic and content differences between the two letter types, and analyse how the identity of Mary Delany is differently constructed and perceived in the explicit autobiographical letters addressed to the Duchess of Portland, and the ones written to her sister. 

  12. Taking Stock: Marie Nimier’s Textual Cabinet of Curiosities

    Directory of Open Access Journals (Sweden)

    Adrienne Angelo

    2014-01-01

    Full Text Available In many life-writing projects, the seemingly innocuous description of heteroclite objects and how those objects are stored and recalled in fact plays an important role in demonstrating their importance to the process of memory work. At once the lingering traces of one’s past and also an aggregation of stories evoked by an examination of them, these curios focus attention on the relationship between the individual and the storage of memories. This article will focus on certain collectibles, collections and collectors that appear throughout the fictional, autobiographical and autofictional world that Marie Nimier has scripted to date. This textual cabinet of curiosities and the act of collecting more generally serve as a trope to connect memory with materiality, despite the numerous narrative voices that Nimier assumes—voices that move from a first-person “Marie Nimier” to an unnamed, although clearly identifiable first-person and even float between genders. Despite this nominal and narrational fluidity, objects function to guarantee recognition, both for the reader, and, especially, for the author herself. What is at stake in this intertextual assemblage of objects is not only the roles that they play in allowing the narrator to revisit past traumas and loss, but also in connecting the author’s presence to other, more fictionalized voices that above all signify the primacy of life-writing in her corpus.

  13. Mary, a Pipeline to Aid Discovery of Optical Transients

    Science.gov (United States)

    Andreoni, I.; Jacobs, C.; Hegarty, S.; Pritchard, T.; Cooke, J.; Ryder, S.

    2017-09-01

    The ability to quickly detect transient sources in optical images and trigger multi-wavelength follow up is key for the discovery of fast transients. These include events rare and difficult to detect such as kilonovae, supernova shock breakout, and `orphan' Gamma-ray Burst afterglows. We present the Mary pipeline, a (mostly) automated tool to discover transients during high-cadenced observations with the Dark Energy Camera at Cerro Tololo Inter-American Observatory (CTIO). The observations are part of the `Deeper Wider Faster' programme, a multi-facility, multi-wavelength programme designed to discover fast transients, including counterparts to Fast Radio Bursts and gravitational waves. Our tests of the Mary pipeline on Dark Energy Camera images return a false positive rate of 2.2% and a missed fraction of 3.4% obtained in less than 2 min, which proves the pipeline to be suitable for rapid and high-quality transient searches. The pipeline can be adapted to search for transients in data obtained with imagers other than Dark Energy Camera.

  14. Marie Nimier, au cœur du silence

    Directory of Open Access Journals (Sweden)

    Joëlle Papillon

    2012-01-01

    Full Text Available Dans La Reine du silence, Marie Nimier se confronte à la figure de son père, l’écrivain Roger Nimier, mort lorsqu’elle avait cinq ans. Elle y montre le poids qui pèse sur l’enfant d’écrivain, mais aussi celui de l’héritage du secret familial et de l’injonction au silence. La difficulté de l’élaboration de son récit de filiation se révèle dans les constants recommencements et reformulations, qui constituent la marque de la tension angoissante entre l’obligation de dire et celle de taire. In La Reine du silence, Marie Nimier confronts her father’s memory – the writer Roger Nimier, who died when she was five years old. The novel describes the burden of being a writer’s child, along with that of inheriting family secrets and submitting to a code of silence. The difficulty of recounting her relationship with her late father is evidenced by the narrator’s numerous “false starts” and her constant rewritings. The hesitant nature of the narration captures an anguish born of two irreconcilable obligations : the need to put things into words and the pressure to remain silent.

  15. Charcot-Marie-Tooth disease: genetic and rehabilitation aspects

    Directory of Open Access Journals (Sweden)

    Mariana CEVEI

    2008-05-01

    Full Text Available Charcot-Marie-Tooth hereditary motor and sensory neuropathy refers to a group of disorders characterized by a chronic motor and sensory polyneuropathy. Typical cases have distal muscle weakness and peroneal atrophy often associated with mild to moderate sensory loss, depressed tendon reflexes, and pes cavus. Hereditary neuropathies are categorized by mode of inheritance and chromosomal locus. The diagnosis is based on family history, characteristic findings on physical examination, EMG, nerve conduction velocity testing, and occasionally on nerve biopsy. The disorder shows allelic and non-allelic genetic heterogeneity, thus mutations of different genes leading to the same clinical features. Also, different mutations of the same gene may lead to different phenotypes. Molecular genetic testing is available in clinical laboratories for diagnosis of 7 subtypes of the disease. Genetic counseling and risk assessment depend on the inheritance. We present two cases with Charcot-Marie-Tooth type 1 and type 2 respectively. There is no cure for the disorder, although physical therapy and moderate activity are often recommended to maintain muscle strength and endurance.

  16. A lecture by Saul Perlmutter, winner of the 2011 Nobel prize in physics

    CERN Multimedia

    2011-01-01

    The CNRS National Institute of Nuclear Physics and Particle Physics (IN2P3), Pierre et Marie Curie University and the Laboratory of Nuclear and High-energy Physics (LPNHE) are happy to invite you to a talk by Nobel laureate Saul Perlmutter.   Perlmutter shared the 2011 Nobel prize in physics "for the discovery of the accelerating expansion of the Universe through observations of distant supernovae." He will give a public talk in Paris on 17 December at 5pm: "Supernovae, Dark Energy, and the Accelerating Universe" Amphithéâtre Farabeuf des Cordeliers 21, rue de l’école de Médecine 75006 Paris Free entrance (places are limited) and live translation available.

  17. Antoni Quintana-Mari (1907-1998): A Pioneer of the Use of History of Science in Science Education

    Science.gov (United States)

    Roca-Rosell, Antoni; Grapi-Vilumara, Pere

    2010-01-01

    In the early 1930s, the young Antoni Quintana-Mari undertook some research on Antoni de Marti i Franques, one of the most prominent Catalan scientists of the Enlightenment. This scientist worked in Tarragona, where Quintana-Mari lived. Quintana-Mari learnt about Marti i Franques from Josep Estalella, his teacher of physics and chemistry at the…

  18. Learning and Stabilization of Winner-Take-All DynamicsThrough Interacting Excitatory and Inhibitory Plasticity

    Directory of Open Access Journals (Sweden)

    Jonathan eBinas

    2014-07-01

    Full Text Available Winner-Take-All (WTA networks are recurrently connected populations of excitatory and inhibitory neurons that represent promising candidate microcircuits for implementing cortical computation. WTAs can perform powerful computations, ranging from signal-restoration to state-dependent processing. However, such networks require fine-tuned connectivity parameters to keep the network dynamics within stable operating regimes. In this article, we show how such stability can emerge autonomously through an interaction of biologically plausible plasticity mechanisms that operate simultaneously on all excitatory and inhibitory synapses of the network. A weight-dependent plasticity rule is derived from the triplet spike-timing dependent plasticity model, and its stabilization properties in the mean-field case are analyzed using contraction theory. Our main result provides simple constraints on the plasticity rule parameters, rather than on the weights themselves, which guarantee stable WTA behavior. The plastic network we present is able to adapt to changing input conditions, and to dynamically adjust its gain, therefore exhibiting self-stabilization mechanisms that are crucial for maintaining stable operation in large networks of interconnected subunits. We show how distributed neural assemblies can adjust their parameters for stable WTA function autonomously while respecting anatomical constraints on neural wiring.

  19. Versatile Networks of Simulated Spiking Neurons Displaying Winner-Take-All Behavior

    Directory of Open Access Journals (Sweden)

    Yanqing eChen

    2013-03-01

    Full Text Available We describe simulations of large-scale networks of excitatory and inhibitory spiking neurons that can generate dynamically stable winner-take-all (WTA behavior. The network connectivity is a variant of center-surround architecture that we call center-annular-surround (CAS. In this architecture each neuron is excited by nearby neighbors and inhibited by more distant neighbors in an annular-surround region. The neural units of these networks simulate conductance-based spiking neurons that interact via mechanisms susceptible to both short-term synaptic plasticity and STDP. We show that such CAS networks display robust WTA behavior unlike the center-surround networks and other control architectures that we have studied. We find that a large-scale network of spiking neurons with separate populations of excitatory and inhibitory neurons can give rise to smooth maps of sensory input. In addition, we show that a humanoid Brain-Based-Device (BBD under the control of a spiking WTA neural network can learn to reach to target positions in its visual field, thus demonstrating the acquisition of sensorimotor coordination.

  20. Winners and losers: Ecological and biogeochemical changes in a warming ocean

    Science.gov (United States)

    Dutkiewicz, S.; Scott, J. R.; Follows, M. J.

    2013-04-01

    We employ a marine ecosystem model, with diverse and flexible phytoplankton communities, coupled to an Earth system model of intermediate complexity to explore mechanisms that will alter the biogeography and productivity of phytoplankton populations in a warming world. Simple theoretical frameworks and sensitivity experiments reveal that ecological and biogeochemical changes are driven by a balance between two impacts of a warming climate: higher metabolic rates (the "direct" effect), and changes in the supply of limiting nutrients and altered light environments (the "indirect" effect). On globally integrated productivity, the two effects compensate to a large degree. Regionally, the competition between effects is more complicated; patterns of productivity changes are different between high and low latitudes and are also regulated by how the supply of the limiting nutrient changes. These complex regional patterns are also found in the changes to broad phytoplankton functional groups. On the finer ecological scale of diversity within functional groups, we find that ranges of some phytoplankton types are reduced, while those of others (potentially minor players in the present ocean) expand. Combined change in areal extent of range and in regionally available nutrients leads to global "winners and losers." The model suggests that the strongest and most robust signal of the warming ocean is likely to be the large turnover in local phytoplankton community composition.

  1. Winners of the Skylab Student Program at Marshall Space Flight Center

    Science.gov (United States)

    1972-01-01

    One of the most successful of the Skylab educational efforts was the Skylab Student Project. A nationwide scientific competition was sponsored by the National Science Teachers Association and the National Aeronautics and Space Administration (NASA) in which secondary students were encouraged to submit proposals for experiments to be conducted on Skylan in Earth orbit the following year. After the official announcement of this project, over 4,000 students responded with 3,409 proposals. The winning 25 students, along with their parents and sponsor teachers, visited Marshall Space Flight Center (MSFC), the lead center for Skylab, where they met with scientists and engineers, participated in design reviews for their experiments, and toured MSFC facilities. Of the 25 students, 6 did not see their experiments conducted on Skylab because the experiments were not compatible with Skylab hardware and timelines. Of the 19 remaining, 11 experiments required the manufacture of additional equipment. This photograph is a group shot of the 25 winners, parents, and sponsors when they met for the first time on the steps of Building 4200 at MSFC in the Spring of 1972.

  2. Selective positive-negative feedback produces the winner-take-all competition in recurrent neural networks.

    Science.gov (United States)

    Li, Shuai; Liu, Bo; Li, Yangming

    2013-02-01

    The winner-take-all (WTA) competition is widely observed in both inanimate and biological media and society. Many mathematical models are proposed to describe the phenomena discovered in different fields. These models are capable of demonstrating the WTA competition. However, they are often very complicated due to the compromise with experimental realities in the particular fields; it is often difficult to explain the underlying mechanism of such a competition from the perspective of feedback based on those sophisticate models. In this paper, we make steps in that direction and present a simple model, which produces the WTA competition by taking advantage of selective positive-negative feedback through the interaction of neurons via p-norm. Compared to existing models, this model has an explicit explanation of the competition mechanism. The ultimate convergence behavior of this model is proven analytically. The convergence rate is discussed and simulations are conducted in both static and dynamic competition scenarios. Both theoretical and numerical results validate the effectiveness of the dynamic equation in describing the nonlinear phenomena of WTA competition.

  3. STDP Installs in Winner-Take-All Circuits an Online Approximation to Hidden Markov Model Learning

    Science.gov (United States)

    Kappel, David; Nessler, Bernhard; Maass, Wolfgang

    2014-01-01

    In order to cross a street without being run over, we need to be able to extract very fast hidden causes of dynamically changing multi-modal sensory stimuli, and to predict their future evolution. We show here that a generic cortical microcircuit motif, pyramidal cells with lateral excitation and inhibition, provides the basis for this difficult but all-important information processing capability. This capability emerges in the presence of noise automatically through effects of STDP on connections between pyramidal cells in Winner-Take-All circuits with lateral excitation. In fact, one can show that these motifs endow cortical microcircuits with functional properties of a hidden Markov model, a generic model for solving such tasks through probabilistic inference. Whereas in engineering applications this model is adapted to specific tasks through offline learning, we show here that a major portion of the functionality of hidden Markov models arises already from online applications of STDP, without any supervision or rewards. We demonstrate the emergent computing capabilities of the model through several computer simulations. The full power of hidden Markov model learning can be attained through reward-gated STDP. This is due to the fact that these mechanisms enable a rejection sampling approximation to theoretically optimal learning. We investigate the possible performance gain that can be achieved with this more accurate learning method for an artificial grammar task. PMID:24675787

  4. "Inhumanly brought back to life and misery": Mary Wollstonecraft, Frankenstein, and the Royal Humane Society.

    Science.gov (United States)

    Williams, C

    2001-01-01

    While thorough investigation of many aspects of contemporary scientific developments and Mary Shelley's personal history have provided illuminating contexts for the study of Frankenstein, the activities of the Royal Humane Society, and other bodies and individuals who pioneered and publicized resuscitation techniques, have been comparatively neglected. Here we find a richly documented, highly conspicuous area of scientific endeavour, which generated much excitement in life and literature from the last quarter of the eighteenth century onwards. There are three major points of contact with Frankenstein: Victor Frankenstein's revival of dead tissue to make his creature; the frequent occurrences of unconsciousness and asphyxia, both in the novel and in Mary Shelley's family during the period leading up to its composition, and the widely differing degrees of competence and success with which they are treated; and the possibility that resuscitative techniques were used to revive Mary Shelley's mother, Mary Wollstonecraft, after a suicide attempt. The impact on Frankenstein of Mary Shelley's lifelong distress at the role she played in bringing about her mother's death in childbirth has been thoroughly canvassed by other critics, notably Anne Mellor, but the thought that Mary Shelley, who was herself conceived after her mother's second suicide attempt, might be, in a sense, a child of the dead adds a further turn to the Gothic screw. This study traces a hitherto unexplored intersection between Mary Shelley's first novel and her family history, as well as showing how it launches a formidable attack on the shady ethics and inconsiderate arrogance of some early resuscitators.

  5. Hand weakness in Charcot-Marie-Tooth disease 1X.

    LENUS (Irish Health Repository)

    Arthur-Farraj, P J

    2012-07-01

    There have been suggestions from previous studies that patients with Charcot-Marie-Tooth disease (CMT) have weaker dominant hand muscles. Since all studies to date have included a heterogeneous group of CMT patients we decided to analyse hand strength in 43 patients with CMT1X. We recorded handedness and the MRC scores for the first dorsal interosseous and abductor pollicis brevis muscles, median and ulnar nerve compound motor action potentials and conduction velocities in dominant and non-dominant hands. Twenty-two CMT1X patients (51%) had a weaker dominant hand; none had a stronger dominant hand. Mean MRC scores were significantly higher for first dorsal interosseous and abductor pollicis brevis in non-dominant hands compared to dominant hands. Median nerve compound motor action potentials were significantly reduced in dominant compared to non-dominant hands. We conclude that the dominant hand is weaker than the non-dominant hand in patients with CMT1X.

  6. Mari Paz Corominas. "Sola en lugares de agua"

    OpenAIRE

    Asins, Consuelo

    1999-01-01

    Una canción suena en los tocadiscos de medio mundo; "sittin'on" (1). La voz que se escucha murió el año pasado. Otis Reding perdió la vida en un accidente de aviación sin saber que la última canción que grababa se convertiría en un su-per-ventas en 1968, y en un clásico que se alargaría hasta acariciar los oídos del 2000. 1968, México, Olimpiadas y Mari paz Corominas, la primera mujer española que consiguió llegar a una final olímpica en natación. Las hadas o las brujas quisieron que el 68 fu...

  7. The lives of Mary Foote: painter and Jungian.

    Science.gov (United States)

    Trousdell, Richard

    2016-11-01

    Mary Foote (1872-1968) was a successful early twentieth century American artist who suddenly closed her New York studio in 1926 to go to Zurich to study with Jung. There she joined his 'Interpretation of Visions' seminars (1930-1934), which she recorded and edited. This work won Jung's praise and his friendship, but all too often Foote was seen merely as a secretary or background figure. Deirdre Bair's biography of Jung suggested that Foote's life and work deserved fuller study, if only to rebalance our view of Jung's early women followers. This paper takes up that work to ask how Foote's early life and career led to her important work in preserving and describing Jung's earliest attempts to apply his theories to clinical practice. © 2016, The Society of Analytical Psychology.

  8. Migration and Metamorphosis in Marie Ndiaye's Trois Femmes Puissantes

    Directory of Open Access Journals (Sweden)

    Deborah B. Gaensbauer

    2014-01-01

    Full Text Available In her 2009 Goncourt-Prize-winning novel, Trois femmes puissantes ( Three Strong Women, Marie Ndiaye experiments with a polyphonic, semi-fantastical rendering of identity-threatening displacements experienced by three women from different socio-geographic backgrounds. In a brief "Counterpoint" at the end of each of the novel's three sections--a narrative take on the musical technique employed by Ndiaye to introduce new focalizations and unexpected turns of events that complicate interpretations of the characters' behavior--each of the women is perceived as metamorphosed into a bird or a birdlike persona. This essay examines the innovative embedding of the shape-shifts in Trois femmes puissantes in both harrowing socio-political realities and the ambiguities of the fantastic and superstition to convey the dehumanizing, unequal power relations governing contemporary women's migration struggles.

  9. Prospective Study of Muscle Cramps in Charcot Marie Tooth Disease

    Science.gov (United States)

    Johnson, Nicholas E; Sowden, Janet; Dilek, Nuran; Eichinger, Katy; Burns, Joshua; McDermott, Michael P; Shy, Michael E.; Herrmann, David N

    2016-01-01

    Introduction This study aims to assess the frequency, location, severity, duration, and fluctuation over time of muscle cramps in Charcot Marie Tooth Disease (CMT). Methods Inherited Neuropathies Consortium Contact Registry participants recorded the occurrence and characteristics of muscle cramps using an 11-question survey administered three times over 8-weeks. Results One hundred and ten adult patients with CMT completed the survey. Weekly cramp frequency was 9.3 (SD 12.3) and 23% had daily muscle cramps. Twenty-two percent reported a significant impact on quality of life. Over 8-weeks, the daily frequency and severity of muscle cramps did not change significantly. Conclusions Patients with CMT have muscle cramps that vary little over an eight-week period, and may interfere with quality of life. These data may be useful in the planning of clinical trials of agents to treat adults with CMT-associated muscle cramps. PMID:25042364

  10. The war of thrones: Elisabeth and Mary Stuart

    Directory of Open Access Journals (Sweden)

    José Renato Ferraz da Silveira

    2013-11-01

    Full Text Available By means of literature research, this article seeks to analyze the historical time of Queen Elisabeth regarding, in particular, the clash with the Scottish queen Mary Stuart. We selected - as cutouts for analysis - conflicts, paradoxes and tensions that underlie the search for legality and legitimacy. In the eternal struggle for power, the characters are faced with political life and death, the rise and decay, the glory and failure, which are inevitable and constitutive stages of the game of thrones. In this study, under a realistic bias, we discuss the triad - conquest maintenance and fall from power - about the shocking and devastating meaning of politic as tragedy in the pursuit of order and harmony in the face of chaos and instability is always present.

  11. Marie Curie: the Curie Institute in Senegal to Nuclear Physics

    Science.gov (United States)

    Gueye, Paul

    Sub-Saharan Africa is not a place where one will look first when radioactivity or nuclear physics is mentioned. Conducting forefront research at the international stage at US national facilities such as the Thomas Jefferson National Accelerator Facility in Virginia or the National Superconducting Cyclotron Facility/Facility for Rare Isotope Beams in Michigan does not point to Historically Black Colleges either. The two are actually intrinsically connected as my personal journey from my early exposure to radiation at the Curie Institute at the LeDantec Hospital in Senegal lead me to Hampton University. The former, through one of my uncles, catapulted me into a nuclear physics PhD while the latter houses the only nuclear physics program at an HBCU to date that has established itself as one of the premier programs in the nation. This talk will review the impact of Marie Curie in my life as a nuclear physicist.

  12. Noncompaction Cardiomyopathy with Charcot-Marie-Tooth Disease

    Directory of Open Access Journals (Sweden)

    Sherif Ali Eltawansy

    2015-01-01

    Full Text Available We report a case of a 53-year-old female presenting with a new-onset heart failure that was contributed secondary to noncompaction cardiomyopathy. The diagnosis was made by echocardiogram and confirmed by cardiac MRI. Noncompaction cardiomyopathy (also known as ventricular hypertrabeculation is a newly discovered disease. It is considered to be congenital (genetic cardiomyopathy. It is usually associated with genetic disorders and that could explain the genetic pathogenesis of the non-compaction cardiomyopathy. Our case had a history of Charcot-Marie-Tooth disease. There is a high incidence of arrhythmia and embolic complications. The treatment usually consists of the medical management, defibrillator placement, and lifelong anticoagulation. Heart transplantation will be the last resort.

  13. Rehabilitation of the Mary Kathleen uranium mining and processing site

    International Nuclear Information System (INIS)

    Ward, T.A.

    1985-09-01

    A detailed plan for the rehabilitation of the Mary Kathleen mining and processing site was developed prior to the closure of operations in late 1982. The plan was based on three basic principles of: making all areas safe for public access; removing all structures which could deteriorate and become unsightly or unsafe with time; and encouraging natural revegetation on erosion resistant surfaces. The aim was to leave the site in a safe and satisfactory condition, consistent with future land use in the area, requiring no foreseeable ongoing maintenance and a minimum of precautionary monitoring. When the programme has been completed, the only constraint on future land use will be the need to control building construction in the tailings/ evaporation, dumps and mine areas as a precaution against possible exposure to radon daughters. Appropriate radiation and water quality monitoring programmes were incorporated in the plan

  14. Rehabilitation of the Mary Kathleen uranium mine site after closure

    International Nuclear Information System (INIS)

    Ward, T.A.; Flannagan, J.C.; Hubery, R.W.

    1983-01-01

    The Mary Kathleen uranium mine and treatment plant ceased operation in late 1982 and a plan for the closure and rehabilitation of the area was developed. The object of the plan is to make all areas safe, remove all non-permanent structures and encourage natural revegetation. The plan has been accepted by the Queensland Mines Department. The mine pit will be left stable, inaccessible to vehicles, and containing about 50 metres of water. Mine waste and borrow areas will be contoured, ripped and seeded to encourage revegetation. The treatment plant area will be cleared of all equipment and light structures, decontaminated and revegetated. The evaporation ponds will be dried out, precipitate and contaminated soil will be removed to the tailings dam, and the area will be contoured and revegetated. The tailings will be covered with one metre of waste rock and boreholes will be used to recover groundwater containing salts for storage in the pit

  15. Mariátegui, Vallejo y la literatura peruana

    OpenAIRE

    Pérez, Alberto Julián

    2007-01-01

    Para enriquecer y superar la comprensión eurocéntrica histórica del fenómeno americano es preciso indagar en la reflexión que sobre éste realizan los propios pensadores de América. En este ocasión, nuestra particular elección ha recaído en José Carlos Mariátegui (1895-1930) y su obra Siete ensayos de interpretación de la realidad peruana (1928). Si bien su pensamiento fue poco formal, estuvo enriquecido por intuiciones y observaciones que aún esperan su oportunidad de tener un papel activo en...

  16. Mary Beard, The Parthenon, Cambridge, Harvard University Press, 2010

    OpenAIRE

    Çelik, Zeynep

    2017-01-01

    À la lumière de récents débats concernant les antiquités, notamment avec la réouverture du Musée de l’Acropole à Athènes, cette édition révisée de l’ouvrage de Mary Beard sur le Parthénon paru en 2002 se montre encore plus percutante que l’originale. Destiné à un large public, y compris des touristes, l’ouvrage livre un panorama fascinant qui englobe architecture, archéologie, histoire culturelle, contextes politiques changeants et la construction de mythes. Partant des histoires anciennes de...

  17. Therapeutic options in Charcot-Marie-Tooth diseases.

    Science.gov (United States)

    Mathis, Stéphane; Magy, Laurent; Vallat, Jean-Michel

    2015-04-01

    Charcot-Marie-Tooth (CMT) diseases represent a heterogeneous genetic disorder (more than 80 genes are implicated in these inherited neuropathies), but sharing a similar phenotype. In recent years, advances in molecular genetics and molecular biology, and also the development of various animal models of CMT, have led to a better understanding. Taken together, this knowledge represents a prerequisite for the development of future therapies in CMT, and in peripheral nervous system disorders in general. The efficacy of various substances has been shown in vitro and also in vivo (in animal models); but, no significant positive effect has yet been confirmed in humans. However, some of these trials are still in development, and we may expect positive results in the future. Although CMT is still an incurable disease, symptomatic treatments (physiotherapy, surgery, analgesic, etc.) are crucial to improve the quality of life of CMT patients.

  18. Charcot-Marie-Tooth: are you testing for proteinuria?

    Science.gov (United States)

    De Rechter, Stéphanie; De Waele, Liesbeth; Levtchenko, Elena; Mekahli, Djalila

    2015-01-01

    Charcot-Marie-Tooth disease (CMT) is a clinically and genetically heterogeneous group of inherited disorders affecting motor and sensory nerves of the peripheral nervous system. CMT has been reported to be associated with renal diseases, mostly focal segmental glomerulosclerosis (FSGS). However, it was unknown whether these two clinical manifestations represent one common underlying disorder or separate disease entities. Several reports have shown a high prevalence of mutations (75%) in the inverted formin gene (INF2) in patients with CMT-associated glomerulopathy, suggesting that these mutations are a common cause of the dual phenotype. For this reason, we strongly suggest to screen for proteinuria in CMT patients, in order to identify patients with this renal-neurologic phenotype in an early stage, and to perform genetic testing for INF2 mutations. Copyright © 2014 European Paediatric Neurology Society. Published by Elsevier Ltd. All rights reserved.

  19. Progress in treatment of Charcot-Marie-Tooth disease

    Directory of Open Access Journals (Sweden)

    Ru-xu ZHANG

    2017-09-01

    Full Text Available Charcot-Marie-Tooth disease (CMT comprises a group of monogenic inherited peripheral neuropathies with highly clinical and genetic heterogeneity, more than 80 causative genes have been cloned at present. Usually starts in childhood or juvinile period, the main clinical manifestations include progressive length.dependent muscle weakness and atrophy, sensory loss, areflexia and pes cavus. Although there is no specific treatment to reverse the natural disease course of CMT, symptomatic treatments such as rehabilitation, orthopedic surgery and medication can improve the overall fitness and life quality of CMT patients. Targeted treatments based on pathogenesis study is expected to provide precise therapy for CMT patients. This paper aims to make a review of the clinical application of symptomatic treatments and progress of target therapy researches in different CMT subtypes. DOI: 10.3969/j.issn.1672-6731.2017.08.003

  20. Winners and losers of national and global efforts to reconcile agricultural intensification and biodiversity conservation.

    Science.gov (United States)

    Egli, Lukas; Meyer, Carsten; Scherber, Christoph; Kreft, Holger; Tscharntke, Teja

    2018-05-01

    Closing yield gaps within existing croplands, and thereby avoiding further habitat conversions, is a prominently and controversially discussed strategy to meet the rising demand for agricultural products, while minimizing biodiversity impacts. The agricultural intensification associated with such a strategy poses additional threats to biodiversity within agricultural landscapes. The uneven spatial distribution of both yield gaps and biodiversity provides opportunities for reconciling agricultural intensification and biodiversity conservation through spatially optimized intensification. Here, we integrate distribution and habitat information for almost 20,000 vertebrate species with land-cover and land-use datasets. We estimate that projected agricultural intensification between 2000 and 2040 would reduce the global biodiversity value of agricultural lands by 11%, relative to 2000. Contrasting these projections with spatial land-use optimization scenarios reveals that 88% of projected biodiversity loss could be avoided through globally coordinated land-use planning, implying huge efficiency gains through international cooperation. However, global-scale optimization also implies a highly uneven distribution of costs and benefits, resulting in distinct "winners and losers" in terms of national economic development, food security, food sovereignty or conservation. Given conflicting national interests and lacking effective governance mechanisms to guarantee equitable compensation of losers, multinational land-use optimization seems politically unlikely. In turn, 61% of projected biodiversity loss could be avoided through nationally focused optimization, and 33% through optimization within just 10 countries. Targeted efforts to improve the capacity for integrated land-use planning for sustainable intensification especially in these countries, including the strengthening of institutions that can arbitrate subnational land-use conflicts, may offer an effective, yet

  1. Aspectos históricos da visita de Marie Sklodowska Curie a Belo Horizonte

    Directory of Open Access Journals (Sweden)

    Cássius Klay Nascimento

    2011-01-01

    Full Text Available In the year 2011 it is celebrated the Marie Sklodowska Curie Nobel Prize centenary and the International Year of Chemistry. However, it is not generally known that Marie Sklodowska Curie, one of the greatest scientists of all time, visited Belo Horizonte, state of Minas Gerais, Brazil. She arrived by train at Belo Horizonte city on 16 August 1926, coming from Rio de Janeiro and accompanied by her daughter Irène Joliot-Curie. The scientists visited the Institute of Radium of Belo Horizonte. The approach in this work emphasizes the presence of Marie Sklodowska Curie in Belo Horizonte, exploring the admiration and respect that people had for her.

  2. Mouse model for Charcot Marie-Tooth as a tool to better understand the disease

    OpenAIRE

    Barneo Muñoz, Manuela

    2016-01-01

    Introducción La enfermedad de Charcot-Marie-Tooth (CMT) es uno de los trastornos neurológicos hereditarios más comunes que afecta a 17-40 de cada 100.000 personas según poblaciones; concretamente esta cifra se sitúa en 28 personas de cada 100.000 en España. La enfermedad recibe el nombre de los tres médicos que la identificaron por primera vez en 1886; Jean-Marie Charcot y Pierre Marie en París, Francia y Howard Henry Tooth en Cambridge, Inglaterra. La enfermedad de CMT, también conocida c...

  3. Igal mõisal on oma lugu / Mari-Ann Remmel

    Index Scriptorium Estoniae

    Remmel, Mari-Ann

    2008-01-01

    Kirjastuselt "Tänapäev" ilmus raamat "Mõisalegendid. Harjumaa", koostaja Mari-Ann Remmel, kujundaja Angelika Schneider. Kogumik sisaldab ka ajaloolist ning genealoogilist teavet mõisahoonete ning -omanike kohta

  4. On the Turn of Two Millennia (60 Years of the Mari Archaeological Expedition

    Directory of Open Access Journals (Sweden)

    Nikitin Valeriy V.,

    2017-03-01

    Full Text Available The article is dedicated to the 60th Anniversary of the Mari Archaeological Expedition and summarizes the two decades of its studies (1996-2016 into the early cultures of the Mari region, starting from the era of the original settlement (Mesolithic, through the Neolithic-Eneolithic, Bronze Age, Early Iron Age and up to the Middle Ages. The expedition studied stations and settlements of primitive cultures, as well as unfortified and fortified settlements and necropolises. Special studies focused on formation and development of the early Mari culture, as well as the material and spiritual culture of the medieval Mari. The expedition continues its survey exploration in order to identify new archaeological sites. During the reported period, twelve monographs were published and three monographs prepared based on the expedition’s materials.

  5. Understanding Employment Discrimination Law: Clarifying Disparate Treatment Analysis after St. Mary's Honor Center V. Hicks

    National Research Council Canada - National Science Library

    Miller, Thomas D

    1994-01-01

    In St. Mary's Honor Center v Hicks, a bitterly divided Supreme Court clashed over the extent and nature of the plaintiff's final burden of persuasion under the McDonnell Douglas Corporation v Green...

  6. Läbi legendide William Shakespeare'i poole / Maris Peters

    Index Scriptorium Estoniae

    Peters, Maris

    2010-01-01

    Tutvustus: Wells, Stanley. Kas on tõsi, et Shakespeare ...? / tõlkinud Maris Peters. Tallinn : Argo, 2010. Raamat William Shakespeare kohta käivatest legendidest, kuuldustest ja teooriatest ning tema teoste autorsusest

  7. Kirjanike aed Nõmme-Rahumäel / Elle-Mari Talivee

    Index Scriptorium Estoniae

    Talivee, Elle-Mari, 1974-

    2016-01-01

    Artur Adsoni ja Marie Underi Rahumäele Vabaduse puiestee ja Veere tänava nurgale ehitatud eramust (arhitekt Edgar Johan Kuusik) ning krundile rajatud iluaiast. Aastast 1944 elasid seal Friedebert ja Elo Tuglas

  8. Surface Elevation and Ice Thickness, Western Marie Byrd Land, Antarctica, Version 1

    Data.gov (United States)

    National Aeronautics and Space Administration — This data set provides surface elevation and ice thickness data for a portion of the Marie Byrd Land sector of West Antarctica, including the Ford Ranges, the...

  9. Mary Loli Martínez-Aldama - Indian Academy of Sciences

    Indian Academy of Sciences (India)

    2016-01-27

    Aldama. Articles written in Journal of Astrophysics and Astronomy. Volume 36 Issue 4 December 2015 pp 457-465 Review. Observations of the Ca I I IR Triplet in High Luminosity Quasars: Exploring the Sample · Mary Loli ...

  10. Precipitation and stream water stable isotope data from the Marys River, Oregon in water year 2015.

    Data.gov (United States)

    U.S. Environmental Protection Agency — Water stable isotope data collected from a range of streams throughout the Marys River basin in water year 2015, and precipitation data collected within the basin at...

  11. Saukas ja Karusoo tõid Marie Underi elu teatrilavale / Andres Laasik

    Index Scriptorium Estoniae

    Laasik, Andres, 1960-2016

    2006-01-01

    20. nov. Kumu auditooriumis esietendunud Ühenduse R.A.A.A.M teatriprojekt "Under" poetess Marie Underist. Lavastajad Merle Karusoo ja Raimo Pass, kunstnik Jaagup Roomet, helilooja Urmas Lattikas, peaosas Katrin Saukas

  12. Ooperi valem : Mari Vihmandi "Armastuse valem" / Evi Arujärv

    Index Scriptorium Estoniae

    Arujärv, Evi, 1953-

    2009-01-01

    Argentiina kirjaniku Esther Vilari romaani "Nina Glucksteini matemaatika" ainetel valminud Mari Vihmandi ooperist "Armastuse valem", libreto Maimu Berg, lavastaja Liis Kolle, tantsu- ja liikumisseaded Ana Mondini. Esietendus 17. oktoobril 2008 Rahvusooperis Estonia

  13. Robert Bresson, Mariano Barroso, Paskaljevich, Mary Harron, David Trueba, Lars von Trier, Liv Ullmann, Zhang Yimou

    OpenAIRE

    La madriguera

    2000-01-01

    La madriguera (2000). Robert Bresson, Mariano Barroso, Paskaljevich, Mary Harron, David Trueba, Lars von Trier, Liv Ullmann, Zhang Yimou. Ediciones de intervención cultural S.L. http://hdl.handle.net/10251/41911. 80 80 33

  14. Mary as Mother in the Flores de Mayo in Poblacion, Oslob

    Directory of Open Access Journals (Sweden)

    Patricia Marion Y. Lopez

    2016-06-01

    Full Text Available The paper reflects on the meanings of the Flores de Mayo ritual as performed in a town on the southeastern coast of Cebu through the examination of Mary as a “semantically open” symbol. The essay illustrates how ideas about Mary are constructed through the discourse of the Church and are in turn, reinforced through a Church-instituted and regulated ritual. An analysis of selected elements of the ritual however, reveals that the symbol of Mary has the potential to hold “other” kinds of meanings that slip in between “official” and “unofficial” discourses, highlighting how Mary continues to be a negotiated field between church authorities and the popular faithful.

  15. Marie-4: A High-Recall, Self-Improving Web Crawler That Finds Images Using Captions

    OpenAIRE

    Rowe, Neil C.

    2002-01-01

    Marie-4, a Web crawler and caption filter, searches the Web to find image captions and the associated image objects. It uses a broad set of criteria to yield higher recall than competing systems, which generally focus on high precision.

  16. The Mesoscale Science of the Matter-Radiation Interactions in Extremes (MaRIE) project

    Energy Technology Data Exchange (ETDEWEB)

    Kippen, Karen Elizabeth [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Montoya, Donald Raymond [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2017-08-17

    The National Nuclear Security Administration (NNSA) requires the ability to understand and test how material structures, defects, and interfaces determine performance in extreme environments such as in nuclear weapons. To do this, MaRIE will be an x-ray source that is laser-like and brilliant with very fl exible and fast pulses to see at weapons-relevant time scales, and with high enough energy to study critical materials. The Department of Energy (DOE) has determined there is a mission need for MaRIE to deliver this capability. MaRIE can use some of the existing infrastructure of the Los Alamos Neutron Science Center (LANSCE) and its accelerator capability. MaRIE will be built as a strategic partnership of DOE national laboratories and university collaborators.

  17. Tarvo Hanno Varres, Mari-Leen Kiipli / Merilin Talumaa, Hanno Soans, Tatjana Kozlova-Johannes

    Index Scriptorium Estoniae

    Talumaa, Merilin, 1986-

    2015-01-01

    Vaatluse alla on võetud Tarvo Hanno Varrese heli- ja videoinstallatsioon "Lindistav põrand" (2015) ja heli- ja videoteos "Betweenland" (2014) ning Mari-Leen Kiipli fotoseeria "The school of dreams" (2012-2015)

  18. Charcot Marie Tooth disease type 4J with complex central nervous system features.

    Science.gov (United States)

    Orengo, James P; Khemani, Pravin; Day, John W; Li, Jun; Siskind, Carly E

    2018-02-01

    We describe a family with Charcot Marie Tooth disease type 4J presenting with features of Charcot Marie Tooth disease plus parkinsonism and aphemia. Genetic testing found two variants in the FIG4 gene: c.122T>C (p.I41T) - the most common Charcot Marie Tooth disease type 4J variant - and c.1949-10T>G (intronic). Proband fibroblasts showed absent FIG4 protein on western blot, and skipping of exon 18 by RT-PCR. As most patients with Charcot Marie Tooth disease type 4J do not have central nervous system deficits, we postulate the intronic variant and I41T mutation together are causing loss of FIG4 protein and subsequently the central nervous system findings in our family.

  19. De novo PMP2 mutations in families with type 1 Charcot-Marie-Tooth disease.

    Science.gov (United States)

    Motley, William W; Palaima, Paulius; Yum, Sabrina W; Gonzalez, Michael A; Tao, Feifei; Wanschitz, Julia V; Strickland, Alleene V; Löscher, Wolfgang N; De Vriendt, Els; Koppi, Stefan; Medne, Livija; Janecke, Andreas R; Jordanova, Albena; Zuchner, Stephan; Scherer, Steven S

    2016-06-01

    We performed whole exome sequencing on a patient with Charcot-Marie-Tooth disease type 1 and identified a de novo mutation in PMP2, the gene that encodes the myelin P2 protein. This mutation (p.Ile52Thr) was passed from the proband to his one affected son, and segregates with clinical and electrophysiological evidence of demyelinating neuropathy. We then screened a cohort of 136 European probands with uncharacterized genetic cause of Charcot-Marie-Tooth disease and identified another family with Charcot-Marie-Tooth disease type 1 that has a mutation affecting an adjacent amino acid (p.Thr51Pro), which segregates with disease. Our genetic and clinical findings in these kindred demonstrate that dominant PMP2 mutations cause Charcot-Marie-Tooth disease type 1. © The Author (2016). Published by Oxford University Press on behalf of the Guarantors of Brain. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  20. Ernest Orlando Lawrence Awards Ceremony for 2011 Award Winners (Presentations, including remarks by Energy Secretary, Dr. Steven Chu)

    International Nuclear Information System (INIS)

    Chu, Steven

    2012-01-01

    The winners for 2011 of the Department of Energy's Ernest Orlando Lawrence Award were recognized in a ceremony held May 21, 2012. Dr. Steven Chu and others spoke of the importance of the accomplishments and the prestigious history of the award. The recipients of the Ernest Orlando Lawrence Award for 2011 are: Riccardo Betti (University of Rochester); Paul C. Canfield (Ames Laboratory); Mark B. Chadwick (Los Alamos National Laboratory); David E. Chavez (Los Alamos National Laboratory); Amit Goyal (Oak Ridge National Laboratory); Thomas P. Guilderson (Lawrence Livermore National Laboratory); Lois Curfman McInnes (Argonne National Laboratory); Bernard Matthew Poelker (Thomas Jeffereson National Accelerator Facility); and Barry F. Smith (Argonne National Laboratory).

  1. The seminal role played by Pierre Marie in Neurology and Internal Medicine

    Directory of Open Access Journals (Sweden)

    Gustavo M Almeida

    2015-10-01

    Full Text Available The authors review the most important contributions of Pierre Marie to the elucidation and description of several neurological diseases, such as Charcot-Marie-Tooth’s disease and hereditary cerebellar ataxia, as well as his contributions to Internal Medicine, including his pioneering studies on acromegaly, ankylosing spondylitis, and hypertrophic pulmonary osteoarthropathy. His works led to incontestable advances in the medical sciences that transcended his time.

  2. A vertente editorial do projeto socialista de Mariátegui

    OpenAIRE

    Streich, Ricardo Neves

    2012-01-01

    Este artigo se propôe a analisar as características centrais da proposta socialista concebida pelo peruano José Carlos Mariátegui por meio de suas diversas iniciativas editoriais.ABSTRACT: This article aims to analyze the main aspects of the socialist approach conceived by the Peruvian José Carlos Mariátegui through his publishing initiatives in this political project.KEYWORDS: MARIÁTEGUI, LATIN-AMERICA SOCIALISM, AMAUTA MAGAZINE.

  3. X-linked Charcot-Marie-Tooth disease predominates in a cohort of multiethnic Malaysian patients.

    Science.gov (United States)

    Shahrizaila, Nortina; Samulong, Sarimah; Tey, Shelisa; Suan, Liaw Chiew; Meng, Lao Kah; Goh, Khean Jin; Ahmad-Annuar, Azlina

    2014-02-01

    Data regarding Charcot-Marie-Tooth disease is lacking in Southeast Asian populations. We investigated the frequency of the common genetic mutations in a multiethnic Malaysian cohort. Patients with features of Charcot-Marie-Tooth disease or hereditary liability to pressure palsies were investigated for PMP22 duplication, deletion, and point mutations and GJB1, MPZ, and MFN2 point mutations. Over a period of 3 years, we identified 25 index patients. A genetic diagnosis was reached in 60%. The most common were point mutations in GJB1, accounting for X-linked Charcot-Marie-Tooth disease (24% of the total patient population), followed by PMP22 duplication causing Charcot-Marie-Tooth disease type 1A (20%). We also discovered 2 novel GJB1 mutations, c.521C>T (Proline174Leucine) and c.220G>A (Valine74Methionine). X-linked Charcot-Marie-Tooth disease was found to predominate in our patient cohort. We also found a better phenotype/genotype correlation when applying a more recently recommended genetic approach to Charcot-Marie-Tooth disease. Copyright © 2013 Wiley Periodicals, Inc.

  4. Genetic epidemiology of Charcot-Marie-Tooth disease.

    Science.gov (United States)

    Braathen, G J

    2012-01-01

    Charcot-Marie-Tooth disease (CMT) is the most common inherited disorder of the peripheral nervous system. The frequency of different CMT genotypes has been estimated in clinic populations, but prevalence data from the general population is lacking. Point mutations in the mitofusin 2 (MFN2) gene has been identified exclusively in Charcot-Marie-Tooth disease type 2 (CMT2), and in a single family with intermediate CMT. MFN2 point mutations are probably the most common cause of CMT2. The CMT phenotype caused by mutation in the myelin protein zero (MPZ) gene varies considerably, from early onset and severe forms to late onset and milder forms. The mechanism is not well understood. The myelin protein zero (P(0) ) mediates adhesion in the spiral wraps of the Schwann cell's myelin sheath. X-linked Charcot-Marie Tooth disease (CMTX) is caused by mutations in the connexin32 (cx32) gene that encodes a polypeptide which is arranged in hexameric array and form gap junctions. Estimate prevalence of CMT. Estimate frequency of Peripheral Myelin Protein 22 (PMP22) duplication and point mutations, insertions and deletions in Cx32, Early growth response 2 (EGR2), MFN2, MPZ, PMP22 and Small integral membrane protein of lysosome/late endosome (SIMPLE) genes. Description of novel mutations in Cx32, MFN2 and MPZ. Description of de novo mutations in MFN2. Our population based genetic epidemiological survey included persons with CMT residing in eastern Akershus County, Norway. The participants were interviewed and examined by one geneticist/neurologist, and classified clinically, neurophysiologically and genetically. Two-hundred and thirty-two consecutive unselected and unrelated CMT families with available DNA from all regions in Norway were included in the MFN2 study. We screened for point mutations in the MFN2 gene. We describe four novel mutations, two in the connexin32 gene and two in the MPZ gene. A total of 245 affected from 116 CMT families from the general population of eastern

  5. La fuga negata. Marie Luise Kaschnitz e il nazismo

    Directory of Open Access Journals (Sweden)

    Lucia Mor

    2014-10-01

    Full Text Available Nel gennaio del 1946 la scrittrice tedesca Marie Luise Kaschnitz pubblica sulla neonata rivista “Die Wandlung” (Il cambiamento il saggio Von der Schuld (Sulla colpa nel quale reagisce, a pochi mesi dalla fine della guerra, alle accuse rivolte da più parti ai Tedeschi di aver consentito al nazismo di trascinare il mondo nella tragedia della Seconda Guerra Mondiale. Le pagine della Kaschnitz sono un documento dimenticato del dibattito, ad oggi inconcluso, sul tema della colpa dei Tedeschi che non opposero resistenza al regime di Adolf Hitler: esse non sono recuperate per decidere sulla condanna o sull’assoluzione della scrittrice e di chi con lei si definì ‘vigliacco’ per aver taciuto, bensì per cercare di comprendere le cause dal punto di vista umano del fenomeno della Innere Emigration, causato dal potere paralizzante esercitato dal regime del terrore, che chiuse ai più ogni via di fuga concreta e, soprattutto, la via della coscienza.

  6. Princess Marie Bonaparte, Edgar Allan Poe, and psychobiography.

    Science.gov (United States)

    Warner, S L

    1991-01-01

    Princess Marie Bonaparte was a colorful yet mysterious member of Freud's inner circle of psychoanalysis. In analysis with Freud beginning in 1925 (she was then 45 years old), she became a lay analyst and writer of many papers and books. Her most ambitious task was a 700-page psychobiography of Edgar Allan Poe that was first published in French in 1933. She was fascinated by Poe's gothic stories--with the return to life of dead persons and the eerie, unexpected turns of events. Her fascination with Poe can be traced to the similarity of their early traumatic life experiences. Bonaparte had lost her mother a month after her birth. Poe's father deserted the family when Edgar was two years old, and his mother died of tuberculosis when he was three. Poe's stories helped him to accommodate to these early traumatic losses. Bonaparte vicariously shared in Poe's loss and the fantasies of the return of the deceased parent in his stories. She was sensitive and empathetic to Poe's inner world because her inner world was similar. The result of this psychological fit between Poe and Bonaparte was her psychobiography, The Life and Works of Edgar Allan Poe. It was a milestone in psychobiography but limited in its psychological scope by its strong emphasis on early childhood trauma. Nevertheless it proved Bonaparte a bona fide creative psychoanalyst and not a dilettante propped up by her friendship with Freud.

  7. Trading Places: Mary Shelley’s Argument with Domestic Space

    Directory of Open Access Journals (Sweden)

    Eve M. Lynch

    2013-04-01

    Full Text Available When Mary Shelley began writing The Last Man in 1824 in the wake of her husband Percy Bysshe Shelley’s untimely death, she drew from her close circle of family and friends as models for her main characters. Although it is tempting to view this novel as an autobiographical expiation of the profound sorrow that overwhelmed Shelley at her husband’s death, to do so is to underestimate her prescient political insight and to risk overlooking the complex implications of class and rank that suffuse the position of the narrator, Lionel Verney. While Shelley’s emotions give a passionate appeal to this novel, her intellectual ideas infuse the novel’s powerful critique of British governance. The Last Man is narrated in a political framework in which war and the clash of empires, parliamentary and republican conflict, turbulent revolution, and social and political corruption arrange the fates of the characters. In addition, the plague that silently and invisibly takes over Western Europe and England serves as a spectral process of corrosive malignity from outside, ensnaring all efforts to fix a domestic English system that is collapsing around individuals and the collective.

  8. Charcot-Marie-Tooth Disease Type 2B

    Directory of Open Access Journals (Sweden)

    Şenay Durdu

    2009-06-01

    Full Text Available Chatcot-Marie-Tooth (CMT is also known as peroneal muscular atrophy and hereditary motor-sensory neuropathy (HMSN. It is the most commonly encountered inherited peripheral neuropathy. Actually, CMT is not a single disease, but is a group of disorders with similar symptoms. CMT type 2 is the second most common form after CMT type1. Symptoms usually begin in childhood or early adulthood. Mostly the peripheral nerves of the lower extremities and occasionaly upper extremities may be affected. Motor nerve involvoment induces distal muscle weakness and atrophy in the lower extremities that may result in foot deformities known as foot drop, pes cavus, pes planus, hammer toe etc. As a result of sensorial nevre degeneration, callus, recurrent foot ulcers, osteonecrosis, osteolysis and spontaneous amputation may accompany the disease. The speed of nerve conduction is not changed in the EMG, but axonal type sensorymotor semptoms that lead to a decrease of amplitude. We report here a 55 year old man with recurrent foot ulcers for 33 years and self amputations, whose EMG findings suggest acsonal neuropathy and who also has a 20 year - old son with similar complaints.

  9. Sleep disorders in Charcot-Marie-Tooth disease type 1.

    Science.gov (United States)

    Boentert, Matthias; Knop, Katharina; Schuhmacher, Christine; Gess, Burkhard; Okegwo, Angelika; Young, Peter

    2014-03-01

    Obstructive sleep apnoea (OSA) and restless legs syndrome (RLS) have been reported in Charcot-Marie-Tooth disease (CMT) type 1A and axonal subtypes of CMT, respectively. The aim of this case-control study was to investigate both prevalence and severity of OSA, RLS and periodic limb movements in sleep (PLMS) in adult patients with genetically proven CMT1. 61 patients with CMT1 and 61 insomnic control subjects were matched for age, sex, and Body Mass Index. Neurological disability in patients with CMT was assessed using the Functional Disability Scale (FDS). RLS diagnosis was based on a screening questionnaire and structured clinical interviews. All participants underwent overnight polysomnography. OSA was present in 37.7% of patients with CMT1 and 4.9% of controls (psleep quality. In addition to known risk factors, CMT may predispose to OSA. RLS is highly prevalent not only in axonal subtypes of CMT but also in primarily demyelinating subforms of CMT. PLMS are common in CMT1, but do not significantly impair sleep quality.

  10. Restaging Hysteria: Mary Wigman as Writer and Dancer

    Directory of Open Access Journals (Sweden)

    Laura A. McLary

    2003-06-01

    Full Text Available Mary Wigman was not only a leading proponent of the early twentieth-century Expressionist dance movement, but also a writer of poetry and short poetic prose. Despite her assertion that dance was beyond language, she wrote often about dance in an attempt to articulate the kinesthetic experience of dance through languages. This interdisciplinary study explores the intersection of dance and writing for Wigman, focusing on gender coding in writing and dance within the context of early twentieth-century dialogues. Despite the pervasive equation of (feminine hysteria with dance and (masculine subjectivity with authorship, Wigman engaged in both activities. I argue that Wigman is able to reclaim and redefine the "hysteria" of the dance experience through writing about dance. In her dance poetry, the act of looking at herself in a mirror as she dances allows Wigman to circumvent the traditional objectification through the male gaze experienced by the female dancer. Through the act of writing, Wigman asserts her subjectivity, taking control of the out-of-body experience of dance creation.

  11. Municipio Mariño Estado Nueva Esparta

    Directory of Open Access Journals (Sweden)

    María Medina

    2008-01-01

    Full Text Available Se caracteriza la gastronomía típica margariteña como atractivo turístico del Municipio Mariño, sus componentes: restaurantes, autores, platos y promoción. Para formular recomendaciones que permitan su aprovechamiento. Los fundamentos teóricos se basan en el área turismo y gastronomía, y su importancia para la actividad. La metodología es descriptiva y su diseño es de campo. Como conclusión se tiene que la situación actual de la gastronomía típica margariteña como atractivo turístico del municipio se caracteriza por la falta de información y promoción, la cual no se está aprovechando como atractivo turístico debido a la falta de conocimiento sobre la gastronomía típica margariteña y donde además en los restaurantes del municipio se están modificando las recetas originales.

  12. The contribution of women to radiobiology: Marie Curie and beyond.

    Science.gov (United States)

    Gasinska, Anna

    2016-01-01

    Marie Sklodowska-Curie, an extraordinary woman, a Polish scientist who lived and worked in France, led to the development of nuclear energy and the treatment of cancer. She was the laureate of two Nobel Prizes, the first woman in Europe who obtained the degree of Doctor of Science and opened the way for women to enter fields which had been previously reserved for men only. As a result of her determination and her love of freedom, she has become an icon for many female scientists active in radiation sciences. They are successors of Maria Curie and without the results of their work, improvement in radiation oncology will not be possible. Many of them shared some elements of Maria Curie's biography, like high ethical and moral standards, passionate dedication to work, strong family values, and scientific collaboration with their husbands. The significance of Tikvah Alper, Alma Howard, Shirley Hornsey, Juliana Denekamp, Helen Evans, Eleanor Blakely, Elizabeth L. Travis, Fiona Stewart, Andree Dutreix, Catharine West, Peggy Olive, Ingela Turesson, Penny Jeggo, Irena Szumiel, Eleonor Blakely, Sara Rockwell and Carmel Mothersill contribution to radiation oncology is presented. All the above mentioned ladies made significant contribution to the development of radiotherapy (RT) and more efficient cancer treatment. Due to their studies, new schedules of RT and new types of ionizing radiation have been applied, lowering the incidence of normal tissue toxicity. Their achievements herald a future of personalized medicine.

  13. Understanding Employment Discrimination Law: Clarifying Disparate Treatment Analysis after St. Mary’s Honor Center V. Hicks

    Science.gov (United States)

    1994-04-01

    was a correctional officer at St. Mary’s before his promotion to shift commander, a supervisory position, in 1980. In 1983, MDCHR investigated the...also ordered the correctional officer who escorted the injured inmate to the hospital to write a report on the incident. On March 24, Powell submitted...Mary’s terminated Hicks on June 7. In contrast, St. Mary’s did not discipline Arthur Turney, a white correctional officer , for insubordination to his

  14. Maris Jesse: loodan südamest, et ükski haigla ei pikenda järjekordi / Maris Jesse ; intervjueerinud Liisa Past

    Index Scriptorium Estoniae

    Jesse, Maris, 1968-

    2009-01-01

    Tervishoiuspetsialist, Tervise Arengu Instituudi juht Maris Jesse vastab küsimustele, mis puudutavad haiglavõrgu arengukava võimalikku ümbertegemist, tervishoiusüsteemis olevaid kokkuhoiukohti, HIV-nakkuse levikut ning meetmeid selle piiramiseks ja ennetamiseks majanduskriisi tingimustes, samuti reformi vajalikkust ravkindlustuses

  15. Panna Marie Příborská. Studie k lokálnímu mariánskému kultu

    Czech Academy of Sciences Publication Activity Database

    Císaríková, Klára; Maňas, V.

    2008-01-01

    Roč. 60, č. 3 (2008), s. 255-268 ISSN 0323-2581 Institutional research plan: CEZ:AV0Z90580513 Keywords : the Virgin Mary * the pilgrim place * Příbor Subject RIV: AC - Archeology, Anthropology, Ethnology

  16. Phenotypic Variability of Childhood Charcot-Marie-Tooth Disease.

    Science.gov (United States)

    Cornett, Kayla M D; Menezes, Manoj P; Bray, Paula; Halaki, Mark; Shy, Rosemary R; Yum, Sabrina W; Estilow, Timothy; Moroni, Isabella; Foscan, Maria; Pagliano, Emanuela; Pareyson, Davide; Laurá, Matilde; Bhandari, Trupti; Muntoni, Francesco; Reilly, Mary M; Finkel, Richard S; Sowden, Janet; Eichinger, Katy J; Herrmann, David N; Shy, Michael E; Burns, Joshua

    2016-06-01

    Disease severity of childhood Charcot-Marie-Tooth disease (CMT) has not been extensively characterized, either within or between types of CMT to date. To assess the variability of disease severity in a large cohort of children and adolescents with CMT. A cross-sectional study was conducted among 520 children and adolescents aged 3 to 20 years at 8 universities and hospitals involved in the Inherited Neuropathies Consortium between August 6, 2009, and July 31, 2014, in Australia, Italy, the United Kingdom, and the United States. Data analysis was conducted from August 1, 2014, to December 1, 2015. Scores on the Charcot-Marie-Tooth Disease Pediatric Scale (CMTPedS), a well-validated unidimensional clinical outcome measure to assess disease severity. This instrument includes 11 items assessing fine and gross motor function, sensation, and balance to produce a total score ranging from 0 (unaffected) to 44 (severely affected). Among the 520 participants (274 males) aged 3 to 20 years, CMT type 1A (CMT1A) was the most prevalent type (252 [48.5%]), followed by CMT2A (31 [6.0%]), CMT1B (15 [2.9%]), CMT4C (13 [2.5%]), and CMTX1 (10 [1.9%]). Disease severity ranged from 1 to 44 points on the CMTPedS (mean [SD], 21.5 [8.9]), with ankle dorsiflexion strength and functional hand dexterity test being most affected. Participants with CMT1B (mean [SD] CMTPedS score, 24.0 [7.4]), CMT2A (29.7 [7.1]), and CMT4C (29.8 [8.6]) were more severely affected than those with CMT1A (18.9 [7.7]) and CMTX1 (males: 15.3 [7.7]; females: 13.0 [3.6]) (P < .05). Scores on the CMTPedS tended to worsen principally during childhood (ages, 3-10 years) for participants with CMT4C and CMTX1 and predominantly during adolescence for those with CMT1B and CMT2A (ages, 11-20 years), while CMT1A worsened consistently throughout childhood and adolescence. For individual items, participants with CMT4C recorded more affected functional dexterity test scores than did those with all other types of CMT (P

  17. Images of Marie Curie: How Reputational Entrepreneurs Shape Iconic Identities

    Directory of Open Access Journals (Sweden)

    Lisa Alaimo

    2018-03-01

    Full Text Available Marie Curie holds iconic status both within the scientific community and in the wider cultural imagination and collective memory. The first woman to be awarded a Nobel Prize and the only woman to achieve such an honor twice, Curie is widely celebrated as a female pioneer in the sciences and is held up as a model for all, but particularly women, to emulate. She is revered not only as a ground-breaking scientist, but also as a devoted wife and mother who fostered intellectual passion in her own children, one of whom became the second woman to be honored with the Nobel Prize in Science. Echoing Eva Hemmungs Wirten, we argue that the evolution of Curie’s status over time offers an opportunity to use meta-biography to understand the layered nature of her reputation. We draw on Gary Alan Fine’s theory of reputational entrepreneurship to understand her legacy as a product of collective historical memory. Curie’s legacy was not pre-determined by the fact that she was a successful scientist; in fact, she was shunned by the public in France in 1911 after it was revealed that she, a widow, had engaged in an affair with a fellow married scientist. A meta-biographical analysis reveals considerable effort was put into reputation building by her Curie herself, her commercial sponsor, and family members. To ignore the earlier iterations of her reputation is to underestimate the challenges she faced as a woman in male-dominated science and in a society that judged her by a sexual double standard. Meta-biography, in conjunction with theories of intellectual reputation building and collective memory, allows us to unearth the complicated layers of Curie’s story. It also tells us a great deal about the [sexist] society in which Curie and her supporters had to forge her reputation.

  18. Correlations between silicic volcanic rocks of the St Mary's Islands (southwestern India) and eastern Madagascar

    DEFF Research Database (Denmark)

    Melluso, Leone; Sheth, Hetu C.; Mahoney, John J.

    2009-01-01

    The St Mary's, Islands (southwestern India) expose silicic volcanic and sub-volcanic rocks (rhyolites and granophyric dacites) emplaced contemporaneously with the Cretaceous igneous province of Madagascar, roughly 88-90 Ma ago. I he St Mary's Islands rocks have phenocrysts of plagioclase, clinopy......The St Mary's, Islands (southwestern India) expose silicic volcanic and sub-volcanic rocks (rhyolites and granophyric dacites) emplaced contemporaneously with the Cretaceous igneous province of Madagascar, roughly 88-90 Ma ago. I he St Mary's Islands rocks have phenocrysts of plagioclase...... and isotopic Compositions very close to those of rhyolites exposed between Vatomandry Ilaka and Mananjary in eastern Madagascar, and are distinctly different from rhyolites front other sectors of the Madagascan province. We therefore postulate that the St Mary's and the Vatomandry-Ilaka Mananjary silicic rock...... outcrops were adjacent before the Late Cretaceous rifting that split Madagascar from India, If so, they provide a valuable tool to check and aid traditional Cretaceous India Madagascar reconstructions based on palaeomagnetism, matching Precambrian geological features, and geometric fitting of continental...

  19. A novel recurrent neural network with one neuron and finite-time convergence for k-winners-take-all operation.

    Science.gov (United States)

    Liu, Qingshan; Dang, Chuangyin; Cao, Jinde

    2010-07-01

    In this paper, based on a one-neuron recurrent neural network, a novel k-winners-take-all ( k -WTA) network is proposed. Finite time convergence of the proposed neural network is proved using the Lyapunov method. The k-WTA operation is first converted equivalently into a linear programming problem. Then, a one-neuron recurrent neural network is proposed to get the kth or (k+1)th largest inputs of the k-WTA problem. Furthermore, a k-WTA network is designed based on the proposed neural network to perform the k-WTA operation. Compared with the existing k-WTA networks, the proposed network has simple structure and finite time convergence. In addition, simulation results on numerical examples show the effectiveness and performance of the proposed k-WTA network.

  20. Biomechanical effects of sensorimotor orthoses in adults with Charcot-Marie-Tooth disease.

    Science.gov (United States)

    Wegener, Caleb; Wegener, Katrin; Smith, Richard; Schott, Karl-Heinz; Burns, Joshua

    2016-08-01

    Charcot-Marie-Tooth disease is an inherited neuropathy causing progressive weakness, foot deformity and difficulty walking. Clinical anecdotes suggest orthoses designed on the 'sensorimotor' paradigm are beneficial for improving gait in Charcot-Marie-Tooth disease. Investigate the effect of sensorimotor orthoses on in-shoe and lower limb biomechanics in adults with Charcot-Marie-Tooth disease. Randomised, repeated-measures, exploratory study. Eight males and two females with Charcot-Marie-Tooth disease aged 31-68 years fitted with pedorthic shoes and custom-made sensorimotor orthoses were randomly tested at baseline and after 4 weeks of adaptation. In-shoe three-dimensional multi-segment foot and lower limb kinematics and kinetics were collected as were plantar pressures, electromyography and self-reported comfort, stability, cushioning and preference. Compared to the shoe only condition, sensorimotor orthoses increased midfoot eversion and plantarflexion, increased ankle eversion and produced small but significant changes at the knee and hip indicating increased internal rotation. The orthoses increased medial ground reaction forces and increased pressure at the heel, midfoot and toes. There were minimal effects on electromyography. The sensorimotor orthoses were rated higher for comfort, cushioning, stability and preference. Sensorimotor orthoses produced changes in kinematic, kinetic and pressure variables in adults with Charcot-Marie-Tooth disease and were regarded as more comfortable, cushioned and stable during walking. In this study, the walking ability of patients with Charcot-Marie-Tooth disease improved with the use of foot orthoses designed according to the sensorimotor paradigm. However, the mechanism of action appears to be primarily mechanical in origin. Randomised controlled trials are necessary to evaluate the long-term patient-reported outcomes of sensorimotor orthoses. © The International Society for Prosthetics and Orthotics 2015.

  1. ReUse Republic annab mõistele "uuskasutus" uue tähenduse / Tanel Veenre, Mari Klein

    Index Scriptorium Estoniae

    Veenre, Tanel, 1977-

    2009-01-01

    Moe- ja disainiagentuuri KalaMari uuest kaubamärgist ReUse Republic. Tegu on seisma jäänud brändirõivaste ümberdisainimise ja (uus)kasutusega. Projekti looja Mari Martin, kaasatud 15 eesti disainerit

  2. 77 FR 43644 - Culturally Significant Objects Imported for Exhibition Determinations: “Byzantine Art in the Mary...

    Science.gov (United States)

    2012-07-25

    ... Determinations: ``Byzantine Art in the Mary and Michael Jaharis Galleries of Greek, Roman and Byzantine Art... determine that the objects to be included in the exhibition ``Byzantine Art in the Mary and Michael Jaharis Galleries of Greek, Roman and Byzantine Art'' imported from abroad for temporary exhibition within the...

  3. Rundum artist-run space and its elusive form / Hanna Laura Kaljo, Mari-Leen Kiipli, Kulla Laas ... [jt.

    Index Scriptorium Estoniae

    2015-01-01

    Rundum on 2013. a septembris Tallinnas loodud liikuv loominguline platvorm, mille eesmärgiks on suhestuda erinevate kohtadega, reageerida tühikutele Eesti loomemaastikus ning uurida sealjuures ka omaalgatuslike praktikate võimalikkust kohalikus kontekstis. Vestlusringis Rundumi algatajad Mari-Leen Kiipli, Kulla Laas, Aap Tepper, Mari Volens, Kristina Õllek

  4. Winter Fish Populations in Probable Locations of Air Bubblers in the St. Marys River-Lake Superior Area

    Science.gov (United States)

    1980-09-01

    March, 1980 ........... ............................. .33 vi LIST OF TABL-S (CONCLUDLD) Number Page II Mean Densities of Zoobenthic Macroinvertebrates in... Zoobenthic Macroinvertebrates in Fonar Grab Samples Collected at Station 2 from the St. Marys River, 1979-1980 ......... ........................ .36 13 Mean...Densities of Zoobenthic Macroinvertebrates in Ponar Grab Samples Collected at Station 3 from the St. Marys River, 1979-1980

  5. Mary Queen of Scots as Feminine and National Icon: Depictions in Film and Fiction

    OpenAIRE

    Ágústsdóttir, Ingibjörg

    2013-01-01

    This article focuses on twentieth and twenty-first century depictions of Mary Queen of Scots in film and fiction. It examines the ways in which Mary’s story is presented and in what manner the myths surrounding her personality and actions are either upheld or deconstructed. While the article demonstrates that modern portrayals of Mary tend to follow the long tradition of seeing her as a version of femininity, Mary’s position as a symbol of the victimization of Scotland by England is also disc...

  6. José Carlos Mariátegui y la reforma universitaria

    OpenAIRE

    Melis, Antonio

    2015-01-01

    En una carta de 1927 al escritor Enrique Espinoza (Samuel Glusberg), quien le había solicitado sus datos biográficos, José Carlos Mariátegui escribía, entre otras cosas: "soy un autodidacta [ . . . ] en Europa frecuenté algunos cursos libremente, pero sin decidirme nunca a perder mi carácter extra-universitario y tal vez si hasta anti-universitario". Esta colocación peculiar de Mariátegui, sin embargo, no había impedido, antes bien había tal vez favorecido, su interés precoz y agudo hacia los...

  7. Learning to Honour Their Body and Blood : pilgrims on the Path of Mary Magdalene

    OpenAIRE

    Fedele, Anna

    2006-01-01

    This article describes the beliefs and some of the ritual practices of a group of female pilgrims visiting places in France and Catalonia that they associate with the figure of Mary Magdalene. It pays particular attention to the pilgrim’s process of learning ways to relate to her own body and to her menstrual cycle. Drawing elements from neo-paganism these women reinterpret the meaning of Christian symbols and places. They consider Mary Magdalene both as a forerunner of feminism and as a mode...

  8. Aspectos históricos da visita de Marie Sklodowska Curie a Belo Horizonte

    OpenAIRE

    Nascimento, Cássius Klay; Braga, João Pedro

    2011-01-01

    In the year 2011 it is celebrated the Marie Sklodowska Curie Nobel Prize centenary and the International Year of Chemistry. However, it is not generally known that Marie Sklodowska Curie, one of the greatest scientists of all time, visited Belo Horizonte, state of Minas Gerais, Brazil. She arrived by train at Belo Horizonte city on 16 August 1926, coming from Rio de Janeiro and accompanied by her daughter Irène Joliot-Curie. The scientists visited the Institute of Radium of Belo Horizonte. Th...

  9. 'BRS Mari': nova cultivar de pimenta dedo-de-moça para processamento 'BRS Mari': new hot pepper cultivar for processing

    Directory of Open Access Journals (Sweden)

    Sabrina Isabel C de Carvalho

    2009-12-01

    Full Text Available 'BRS Mari' é uma nova cultivar de pimenta dedo-de-moça desenvolvida para uso múltiplo, como produto in natura, processada na forma de molho líquido ou desidratada em flocos, moída junto com as sementes, para a produção de pimenta tipo 'calabresa'. A cv. 'BRS Mari' foi desenvolvida a partir da população 'CNPH 0039' por meio de seis ciclos de seleção massal com autofecundação controlada. A nova cultivar apresenta plantas de polinização aberta com hábito de crescimento intermediário, com aproximadamente 90 cm de altura e 1,25 m de largura, com resistência múltipla a doenças, com destaque para o virus Pepper Yellow Mosaic Virus (PepYMV e nematóide das galhas (Meloidogyne javanica, resistência mediana ao oídio (Oidium sicula, mancha bacteriana (Xanthomonas spp. e antracnose (Colletotrichum spp.. A colheita dos frutos tem início cerca de 70 dias após o transplante. Nas condições da região Centro-Oeste, 'BRS Mari' apresentou boa uniformidade de planta, ótima qualidade de fruto e grande potencial produtivo, alcançando 35 t ha-1 em seis meses, quando cultivada no espaçamento de 1 m entre plantas e 1,5 m entre linhas. Os frutos são alongados e pendentes, típicos do tipo dedo-de-moça, com passagem de coloração verde claro, amarelo com antocianina e laranja quando imaturos e vermelho intenso quando maduros, com aproximadamente 6,0 cm de comprimento, 1,4 cm de largura e cerca de 1,7 mm de espessura da parede. A principal característica da 'BRS Mari' é o elevado teor de capsaicina, aproximadamente 90.000 SHU (Unidades de Calor Scoville, mais elevado quando comparada com outras cultivares do mesmo grupo.'BRS Mari' is a new hot pepper cultivar suitable for processing as sauce or dehydrated flakes, ordinarily known in Brazil as 'calabresa' type, as well as for fresh market. Hot pepper cv. 'BRS Mari' was obtained from population 'CNPH 0039', through six cycles of mass selection with controlled selfing of selected plants. The

  10. REGARDS PRISMATIQUES DES PERSONNAGES DE MARIE NDIAYE (COMÉDIE CLASSIQUE ET LADIVINE (Prismatic looks of the characters of Marie NDiaye (Comédie classique and Ladivine

    Directory of Open Access Journals (Sweden)

    Andreea-Madalina Neamtu Voicu

    2015-06-01

    Full Text Available Among the oddities that populate the literary world of Marie NDiaye, there is one aspect that plays on the subjectivity of the perspective. This is something that binds two novels of Marie NDiaye apparently totally different. Comédie classique (1987 is written in the first person, with one focalizer who attributes words, gestures, thoughts to those around him. In Ladivine (2013, the writer multiplies voices and glances: there are five perspectives that alternate. Each focalizer works like a prism that breaks the reader’s vision of the characters. The image of the protagonists is therefore built on the tension between the vision of oneself and others, between the desire to appear and the sometimes opaque reality, between the visible and the invisible.

  11. A Rasch Analysis of the Charcot-Marie-Tooth Neuropathy Score (CMTNS) in a Cohort of Charcot-Marie-Tooth Type 1A Patients.

    Science.gov (United States)

    Wang, Wenjia; Guedj, Mickaël; Bertrand, Viviane; Foucquier, Julie; Jouve, Elisabeth; Commenges, Daniel; Proust-Lima, Cécile; Murphy, Niall P; Blin, Olivier; Magy, Laurent; Cohen, Daniel; Attarian, Shahram

    2017-01-01

    The Charcot-Marie-Tooth Neuropathy Score (CMTNS) was developed as a main efficacy endpoint for application in clinical trials of Charcot-Marie-Tooth disease type 1A (CMT1A). However, the sensitivity of the CMTNS for measuring disease severity and progression in CMT1A patients has been questioned. Here, we applied a Rasch analysis in a French cohort of patients to evaluate the psychometrical properties of the CMTNS. Overall, our analysis supports the validity of the CMTNS for application to CMT1A patients though with some limitations such as certain items of the CMTNS being more suitable for moderate to severe forms of the disease, and some items being disordered. We suggest that additional items and/or categories be considered to better assess mild-to-moderate patients.

  12. A Rasch Analysis of the Charcot-Marie-Tooth Neuropathy Score (CMTNS in a Cohort of Charcot-Marie-Tooth Type 1A Patients.

    Directory of Open Access Journals (Sweden)

    Wenjia Wang

    Full Text Available The Charcot-Marie-Tooth Neuropathy Score (CMTNS was developed as a main efficacy endpoint for application in clinical trials of Charcot-Marie-Tooth disease type 1A (CMT1A. However, the sensitivity of the CMTNS for measuring disease severity and progression in CMT1A patients has been questioned. Here, we applied a Rasch analysis in a French cohort of patients to evaluate the psychometrical properties of the CMTNS. Overall, our analysis supports the validity of the CMTNS for application to CMT1A patients though with some limitations such as certain items of the CMTNS being more suitable for moderate to severe forms of the disease, and some items being disordered. We suggest that additional items and/or categories be considered to better assess mild-to-moderate patients.

  13. TOURISM PLANNING OPPORTUNITIES FOR THE SALT LAKES OF OCNELE MARI AND OCNIŢA

    Directory of Open Access Journals (Sweden)

    POPESCU ANTOANETA-CARINA

    2012-03-01

    Full Text Available Tourism Planning Opportunities for The Salt Lakes of Ocnele Mari and Ocniţa. Ocnele Mari used to be a popular balneal tourism destination in the Southern region of Romania, Oltenia. Due to the hilly climate and the two balneal establishments of Ocnele Mari and Ocniţa, tourists could find the necessary natural cure factors for rheumatic and cardiovascular diseases. However, the salt from Ocnele Mari was also used for industrial purposes, being extracted through solution mining, which proved to be detrimental to the environment. Salt underground dissolution caused land subsidence and landslide in the area, together with the formation of large salt lakes. Security became an issue, the number of tourists diminished and the balneal equipment became obsolete because of lack of modernization investment. Under these circumstances, on the basis of field work, we have reached the conclusion that a better planning of the resort and of the salt lakes would contribute to the economic development of the region.

  14. Mari Koger : avatud magamistoaga korter pööningukorrusel / Gitte Hint

    Index Scriptorium Estoniae

    Hint, Gitte

    2003-01-01

    Korter Nõmmel renoveeritud puumajas (arhitekt Hannes Niineväli). Sisearhitekt Mari Koger, tema kommentaarid. Söögilaua alumiiniumist valatud jalgade autor on Taavi Aunre. Söögilauda valgustab Alberto Meda ja Paolo Rizzatto disainitud lamp Titania. Ill.: plaan, 8 värv. vaadet

  15. Mary Carroll Craig Bradford: Providing Opportunities to Colorado's Women and Children through Suffrage and Education

    Science.gov (United States)

    Caldwell, Heather Kleinpeter

    2009-01-01

    This dissertation is a historical biography on the life, suffrage and educational contributions of Mary Carroll Craig Bradford, a wife, mother, suffragist, teacher and educational administrator in the state of Colorado. The purpose of this dissertation was to find out exactly what Bradford's contributions were to her state. The initial observation…

  16. The Gendering of Albert Einstein and Marie Curie in Children's Biographies: Some Tensions

    Science.gov (United States)

    Wilson, Rachel E.; Jarrard, Amber R.; Tippins, Deborah J.

    2009-01-01

    Few twentieth century scientists have generated as much interest as Albert Einstein and Marie Currie. Their lives are centrally depicted in numerous children's biographies of famous scientists. Yet their stories reflect interesting paradoxes and tacit sets of unexplored sociocultural assumptions about gender in science education and the larger…

  17. Rediscovering the Art of Developmental Therapy: An Interview with Mary M. Wood

    Science.gov (United States)

    Teagarden, James M.; Kaff, Marilyn S.; Zabel, Robert H.

    2013-01-01

    Dr. Mary Margaret Wood is best known for developing psychoeducational programs that integrate mental health and special education interventions for children with emotional and behavioral disorders (EBD). Developmental Therapy (DT) includes comprehensive assessment of student behavior, communication, social, and cognitive development,…

  18. Sisters in Restaurant Success: A history of The Maramor, Mary Love's Tea Room

    OpenAIRE

    Jan Whitaker

    2017-01-01

    In 1920, Mary Love opened The Maramor, a tea room style restaurant in Columbus, Ohio that quickly become recognized as one of the country's fine restaurants. Her career is intertwined with the rise of home economics college programs, helping women gain a new-born confidence that was used to dominate the restaurant and catering industry.

  19. Mary Cassatt: Celebrating Everyday Life. Teacher's Guide. School Arts: Looking/Learning.

    Science.gov (United States)

    Denker, Eric

    Mary Cassatt's paintings and graphics depict the world of 19th-century women, mothers, and children. Her exploration of intimate domestic life is informed by an unsurpassed ability to capture the natural, sometimes awkward poses of her figures and her refusal to "prettify" her subjects. This teaching guide gives an overview of Cassatt's…

  20. Mary Mitchell Slessor (1848 – 1915) and Her Impact on the ...

    African Journals Online (AJOL)

    1848-12-02

    Born December 2, 1848 in Gilcomston, Aberdeen, Scotland, MARY Mitchell Slessor, a five foot, red haired Scottish Missionary who pioneered her way into the jungles of Africa was undoubtedly one of the most outstanding missionaries who made tremendous contributions to evangelism, charity work, educational and ...

  1. Mary Wollstonecraft, Margaret Fuller, and Angelina Grimke: Symbolic Convergence and a Nascent Rhetorical Vision.

    Science.gov (United States)

    Huxman, Susan Schultz

    1996-01-01

    Invites rhetorical critics to reappraise the way they study discreet social movements and pay isolated tribute to woman's rights figures. Examines how Mary Wollstonecraft, Margaret Fuller, and Angelina Grimke each co-opted the ideational and stylistic rhetorical characteristics of pre-existing social movements (the enlightenment,…

  2. Mary Wollstonecraft's "Rational Education" Agenda and the Status of Women in Eighteenth Century England.

    Science.gov (United States)

    Roberts, Leonard H.

    This paper describes the life of Mary Wollstonecraft, the pioneer feminist, author, and educator in 18th century England and how the influences of rational education caused her to be an advocate of women's education beyond social deportment and menial activities. Wollstonecraft believed that education should be built on strengthening a women's…

  3. Rhetorcizing Alienation: Mary Wollstonecraft and the Rhetorical Construction of Women's Oppression.

    Science.gov (United States)

    Griffin, Cindy L.

    1994-01-01

    Advances a "rhetoricized" conception of alienation through the work of Mary Wollstonecraft, a British feminist writing in the 1790s. Suggests that alienation is a discursive problem posed by the interpolation of women throughout history and the reification of those interpolations over time. Shows how alienation functions as a critical…

  4. Women's Emancipation through Education: The Radical Agenda of Mary Wollstonecraft (1759-1797).

    Science.gov (United States)

    Roberts, Leonard H.; Pollman, Mary Jo

    Two hundred years ago, Mary Wollstonecraft, the English women's rights pioneer, published her immortal work: "A Vindication of the Rights of Woman." In it she placed much of the blame for women's inferior political, intellectual, and social status on "faulty education." In "Vindication," she offered a number of…

  5. Women, Education and the Material Body Politic in Mary Wollstonecraft's "Vindications"

    Science.gov (United States)

    Bernath, Elizabeth

    2016-01-01

    This paper discusses Mary Wollstonecraft's "A Vindication of the Rights of Woman: With Strictures on Political and Moral Subjects" and "A Vindication of the Rights of Men" as books of philosophy about rational materialism. Based on an analysis of Lockean thought, as applied to the possibility of women's development of reason,…

  6. Kunsti kuumtöötlus Läti aladel / Mari Sobolev

    Index Scriptorium Estoniae

    Sobolev, Mari, 1968-

    2004-01-01

    Pedvale vabaõhumuuseumis toimunud rahvusvahelisest workshop'ist teemal "Kompost", mille tulemusi presenteeriti 6. VIII 2004. Ignas Kazakeviciuse, Jurate Rakeviciute, Diana Dimzha-Dime, Ule Björn Gundermanni, Remo Randveri, Maris Grosbahsi, Andrus Joonase töödest

  7. Living Proof: What Helen Keller, Marilyn Monroe, and Marie Curie Have in Common.

    Science.gov (United States)

    Saul, E. Wendy

    1986-01-01

    Examines biographies of Marie Curie written for children and discusses two types of distortions: simple misrepresentations of fact and selective retelling of the past. It is concluded that biographies of minority or female success should deal specifically with strategies used by the hero or heroine to combat prejudice. (EM)

  8. Strangers and Orphans: Knowledge and Mutuality in Mary Shelley's "Frankenstein"

    Science.gov (United States)

    Gomez, Claudia Rozas

    2013-01-01

    Paulo Freire consistently upheld humanization and mutuality as educational ideals. This article argues that conceptualizations of knowledge and how knowledge is sought and produced play a role in fostering humanization and mutuality in educational contexts. Drawing on Mary Shelley's novel "Frankenstein," this article focuses on the…

  9. Sotsiaalset kaitset võib vajada igaüks / Maris Jesse, Anu Toots, Tõnis Kõiv

    Index Scriptorium Estoniae

    Jesse, Maris, 1968-

    2009-01-01

    Sotsiaalpoliitika asjatundjad Eesti sotsiaalsüsteemi probleemidest ja arenguteedest. Vestlusringist võtsid osa Tervise Arengu Instituudi direktor Maris Jesse, Tallinna Ülikooli riigiteaduste instituudi võrdleva halduspoliitika professor Anu Toots ja Riigikogu sotsiaalkomisjoni liige Tõnis Kõiv. Vestlusringi juhtis RiTO peatoimetaja Helle Ruusing

  10. Women in History: Mary Parker Follett--A Leadership Theorist Ahead of Her Time

    Science.gov (United States)

    Gaspar, Sandy

    2004-01-01

    This article profiles Mary Parker Follet, a management and leadership voice in the 1920s and 30s who was far ahead of her time. Throughout her lifetime, Follet refused to accept the dualities and dichotomies that threatened to divide individuals and organizations. In her book, "The New State," Follet argued that group organization and…

  11. Response to Marie Paz Morales' ``Influence of culture and language sensitive physics on science attitude achievement''

    Science.gov (United States)

    Cole, Mikel Walker

    2015-12-01

    This response to Marie Paz Morales' "Influence of culture and language sensitive physics on science attitude achievement" explores the ideas of culturally responsive pedagogy and critical literacy to examine some implications for culturally responsive science instruction implicit in the original manuscript.

  12. From Mary Virginia Gaver to the CLASS Research Summit: A Journey toward Causality and Student Success

    Science.gov (United States)

    Soulen, Rita R.

    2016-01-01

    Mary Virginia Gaver conducted the first correlational research in the field of school libraries. Many in the field trace the beginning of the search for proof that effective school libraries impact student learning to her study published just over fifty years ago. While conducting her study she developed measures of the effectiveness of school…

  13. Welcoming the Sunlight: A Conversation with Mary Kay Zabel and Robert Zabel

    Science.gov (United States)

    Teagarden, James; Kaff, Marilyn

    2018-01-01

    Professors Emeriti Mary Kay and Robert Zabel share their reflections on their long and productive careers working with students and teachers. Their respective careers share much of the same history and complement each other. The Zabels share their advice with those entering the field and the challenges they see for the education of students with…

  14. Women, Education and the Material Body Politic in Mary Wollstonecraft's "Vindications"

    Science.gov (United States)

    Bernath, Elizabeth

    2016-01-01

    This paper discusses Mary Wollstonecraft's "A Vindication of the Rights of Woman: With Strictures on Political and Moral Subjects" and "A Vindication of the Rights of Men" as books of philosophy about rational materialism. Based on an analysis of Lockean thought, as applied to the possibility of women's development of reason,…

  15. Muuga / Mary von Grünewaldt ; tõlk. Mati Sirkel

    Index Scriptorium Estoniae

    Grünewaldt, Mary von

    2004-01-01

    Leo Zoegelt ostetud Muuga mõisahoone korrastamisest ja uue hoone ehitamisest C. T. von Neffi kunstikogu paigutamise tarbeks. Tütre mälestused. Tõlgitud raamatust: Skizzen und Bilder aus dem Leben Carl Timoleon von Neff / Mary von Grünewaldt. Darmstadt, 1887

  16. Neuromuscular Hip Dysplasia in Charcot-Marie-Tooth Disease Type 1A

    Science.gov (United States)

    Bamford, Nigel S.; White, Klane K.; Robinett, Stephanie A.; Otto, Randolph K.; Gospe, Sidney M., Jr.

    2009-01-01

    Charcot-Marie-Tooth disease (CMT) is one of the most common inherited neurological disorders, affecting 36 in 100,000 people. CMT type 1A (hereditary motor and sensory neuropathy) is the most frequent form of this disease, affecting 60 to 80% of the CMT population, but its diagnosis may be delayed because of inconsistent clinical signs and…

  17. Making Socialists: Mary Bridges Adams and the Fight for Knowledge and Power, 1855-1939

    Science.gov (United States)

    Weiler, Kathleen

    2012-01-01

    This article presents a review of "Making socialists: Mary Bridges Adams and the fight for knowledge and power, 1855-1939," by Jane Martin. Jane Martin has explored the history of late-nineteenth-century and early-twentieth century-British women educational activists in numerous publications over the past two decades. Her first book,…

  18. Re-Birthing the Monstrous: James Whale's (Mis)Reading of Mary Shelley's "Frankenstein."

    Science.gov (United States)

    Picart, Caroline Joan S.

    1998-01-01

    Contributes to scholarship on film and feminism by showing how James Whale's film attempts to excise or severely delimit the disturbing critique of the Romantic politics of gender in Mary Shelley's novel "Frankenstein." Discusses parthenogenesis, showing how the novel critiques the Romantic rhetorical reconstructions of masculine…

  19. Migrating to the City: Negotiating Gender and Race in Marie Arana's "Lima Nights"

    Science.gov (United States)

    Heredia, Juanita

    2016-01-01

    This article examines Peruvian-American Marie Arana's second novel "Lima Nights" (2008) in which she represents Amazonian indigenous migrations to Lima, Peru during and after the Shining Path civil war years (1986-2006). As part of a generation of transnational US Latina authors in the post-2000 period, Arana recovers the image of the…

  20. Hairy Mary: Natal Government Railways 2-8-2 (Tanic Tender ...

    African Journals Online (AJOL)

    Hairy Mary: Natal Government Railways. 2-8-2 (Tanic Tender Locomotive Havelock) won J.A. Hattingh*. This locomotive was actually a Havelock tank. Tender-Locomotive with the wheel arrangement of 2-8-2. It was designed in 1887 and built in the. Durban workshops. Itwas the first locomotive to be built in South Africa.

  1. Mary Lincoln's Madness: Understanding the Factors that Influence the Diagnosis and Treatment of Bipolar Disorder

    Science.gov (United States)

    Dick, Carina; Renes, Susan L.; Strange, Anthony T.

    2010-01-01

    Mary Lincoln, wife of President Abraham Lincoln, lived a tragic life. Beginning with the death of her mother when she was a little girl, Mrs. Lincoln experienced a number of family deaths, including three brothers, three sons, and the murder of her beloved husband while she sat by his side. In addition to tragedy, Mrs. Lincoln suffered from poor…

  2. Online Opportunist: Mary Ellen Icaza--Montgomery County Public Libraries, Rockville, MD

    Science.gov (United States)

    Library Journal, 2004

    2004-01-01

    When Mary Ellen Icaza became Electronic Services Librarian at Montgomery County Public Libraries, she noticed that the readers' services information on the library web site was invisible, even to librarians. "And if staff can't find it," she says, "customers can't." She set out to help people find that material-and to turn a…

  3. Manifest Destiny's Child: Mary Hazelton Blanchard Wade and the Literature of American Empire

    Science.gov (United States)

    Tunc, Tanfer Emin

    2017-01-01

    This article discusses how, following in the footsteps of United States imperial children's writers Jacob Abbott and Edward Stratemeyer, Mary Hazelton Blanchard Wade (1860-1936), the original author of the "Our Little Cousins" series (1901-1905), contributed to the American culture of empire. Wade was one of the most prolific and popular…

  4. Difficulties in teaching electromagnetism: an eight year experience at Pierre and Marie Curie University

    Directory of Open Access Journals (Sweden)

    H. Roussel

    2012-07-01

    Full Text Available We will begin by outlining the details of how electromagnetics are taught in the  electrical engineering program offered at Pierre and Marie Curie University (a French example from the undergraduate to the Masters degree levels.  We will also discuss how our methods are and should be adapted to teach waves propagation without discouraging students.

  5. Response to Marie Paz Morales' "Influence of Culture and Language Sensitive Physics on Science Attitude Achievement"

    Science.gov (United States)

    Cole, Mikel Walker

    2015-01-01

    This response to Marie Paz Morales' "Influence of culture and language sensitive physics on science attitude achievement" explores the ideas of culturally responsive pedagogy and critical literacy to examine some implications for culturally responsive science instruction implicit in the original manuscript. [For "Influence of…

  6. On the Differentiation of Mari and Permic Place Names in the Vetluga-Vyatka Interfluve Area

    Directory of Open Access Journals (Sweden)

    Alexander L. Pustyakov

    2014-12-01

    Full Text Available The article presents an analysis of place names of the Vetluga-Vyatka interfluve area containing lexemes that can be of either Mari or Permic origin. The paper focuses on the roots shVr, vazh ~ vozh which are frequent in the toponymy of the area, and some names ingluding the lexical component vad / vod / vot. The author establishes the linguistic attribution of the place names in question and suggests possible etymologies for the roots, determiners and names on the whole. In addition to the etymological analysis, the author shows the importance of some general and special principles of toponymic studies as applied to the differentiation of Mari and Permic place names of the Vetluga-Vyatka interfluve area. The author concludes that among the place names containing the component shVr there are those of both Mari and Permic origin, the latter being concentrated in the North-East of the Republic of Mari-El and in the adjacent districts of Kirov region. The author argues that the root vozh was not active in Udmurt toponymy when Udmurt clan groups lived on the right bank of the Vyatka. The article also suggests new hypotheses concerning the origin of some place names containing vad / vod / vot which used to be explained referring to the Komi language.

  7. Uus nobelist : prantslane Jean-Marie Gustave Le Clézio / Kaarel Kressa

    Index Scriptorium Estoniae

    Kressa, Kaarel, 1983-

    2008-01-01

    Nobeli kirjandusauhind 2008 - prantsuse romaanikirjanik Jean-Marie Gustave Le Clézio. Sisaldab autori eesti keelde tõlgitud teoste annotatsioone: Päev, mil Beaumont tegi tutvust oma valuga : [novell] / tlk. Merike Riives (kogumikust Prantsuse novell, 1973); Kõrb / tlk. Kristiina Ross (Eesti Raamat, 1990); Diego ja Frida / tlk. Sirje Keevallik (Kunst, 2007)

  8. Charcot-Marie-Tooth disease: frequency of genetic subtypes and guidelines for genetic testing.

    LENUS (Irish Health Repository)

    Murphy, Sinead M

    2012-07-01

    Charcot-Marie-Tooth disease (CMT) is a clinically and genetically heterogeneous group of diseases with approximately 45 different causative genes described. The aims of this study were to determine the frequency of different genes in a large cohort of patients with CMT and devise guidelines for genetic testing in practice.

  9. 75 FR 22436 - Michael Williams-Control Exemption-St. Maries River Railroad, Inc.

    Science.gov (United States)

    2010-04-28

    ... DEPARTMENT OF TRANSPORTATION Surface Transportation Board [Docket No. FD 35365] Michael Williams-Control Exemption-St. Maries River Railroad, Inc. Michael Williams (applicant),\\1\\ a noncarrier, has filed..., LLC, by Williams Group, Inc. (WG).\\2\\ Applicant currently controls two Class III railroads through...

  10. A SONG TO MARY CHAR ES Stage productions are products of a ...

    African Journals Online (AJOL)

    Tracie1

    Stage productions are products of a theatre menu prepared by the arts of the theatre. Each art of the theatre ..... Kilbride and several others oppose the invitation; painting a faint picture of what the Calabar people are like. ... Act Five tells of Mary Charles return to the Irish. Sisters of Charity in ublin, her preparation to leave for.

  11. The association of uranium and skarn development in the Mary Kathleen area, Queensland

    International Nuclear Information System (INIS)

    Cruikshank, B.I.; Ferguson, J.; Derrick, G.M.

    1980-01-01

    The genesis of both the Mary Kathleen orebody and the garnet-rich skarns appears to be related to the release of the residual, hydrous phase of the crystallising Burstall Granite and associated rhyolite dykes. The fluid introduced many elements, including uranium, into the metasomatic system and possibly remobilised others. Decomposition of carbonate during alteration of marble gave rise to fluids rich in CO 2 ; it appears likely that these fluids transported uranium and the rare-earth elements to a suitable site of deposition, in this case an open-textured conglomerate. Deposition of uraninite and retrograde reaction of garnet to rare-earth-bearing allanite probably occurred during a period of decreasing CO 2 content of the metasomatic-mineralising fluid. The Cahill Formation in the Pine Creek Geosyncline lacks the high temperature skarn-type uranium enrichment found in the Mary Kathleen area, despite the similarity in metamorphic grade and the development of juxtaposed uranium-enriched granitoids. The main difference in lithology in the uranium host formation in the two areas is the predominance of and calcsilicate rocks in the Mary Kathleen area. The calcareous units in the Cahill Formation are volumetrically small compared with those in the Corella Formation at Mary Kathleen. Other differences between the two areas possibly relate to the compositions of the initial fluids associated with the granitoids and to their interaction with host rocks, as well as the involvement of connate hydrous solutions

  12. Magic Women on the Margins: Ec-Centric Models in Mary Poppins and Ms Wiz

    Science.gov (United States)

    Valverde, Cristina Perez

    2009-01-01

    This paper offers a comparative analysis of two characters belonging to the tradition of empowered "spinster" in children's fiction, namely Mary Poppins and Ms Wiz, from the perspective of gender politics and child/adult interactions. A distinction is made between the figure portrayed in P. L. Travers' texts and the Disney film starring Julie…

  13. Walt Disney Meets Mary Daly: Invention, Imagination, and the Construction of Community.

    Science.gov (United States)

    Covino, William A.

    2000-01-01

    Posits Walt Disney as an influential sorcerer in the process of integrating the real world into Disney's synthetic universe, and Mary Daly's work "Wickedary" as a work that constructs an alternative "magic kingdom" through an insistence on an anti-patriarchal lexicon. (NH)

  14. The design and research of anti-color-noise chaos M-ary communication system

    International Nuclear Information System (INIS)

    Fu, Yongqing; Li, Xingyuan; Li, Yanan; Zhang, Lin

    2016-01-01

    Previously a novel chaos M-ary digital communication method based on spatiotemporal chaos Hamilton oscillator has been proposed. Without chaos synchronization circumstance, it has performance improvement in bandwidth efficiency, transmission efficiency and anti-white-noise performance compared with traditional communication method. In this paper, the channel noise influence on chaotic modulation signals and the construction problem of anti-color-noise chaotic M-ary communication system are studied. The formula of zone partition demodulator’s boundary in additive white Gaussian noise is derived, besides, the problem about how to determine the boundary of zone partition demodulator in additive color noise is deeply studied; Then an approach on constructing anti-color-noise chaos M-ary communication system is proposed, in which a pre-distortion filter is added after the chaos baseband modulator in the transmitter and whitening filter is added before zone partition demodulator in the receiver. Finally, the chaos M-ary communication system based on Hamilton oscillator is constructed and simulated in different channel noise. The result shows that the proposed method in this paper can improve the anti-color-noise performance of the whole communication system compared with the former system, and it has better anti-fading and resisting disturbance performance than Quadrature Phase Shift Keying system.

  15. The Marie Curie Actions at CERN – reaching out beyond particle physics and Europe

    CERN Multimedia

    EU Projects Office

    2014-01-01

    The European Commission’s Marie Curie Actions have been a pillar of the EU Framework Programmes for several decades as a means of promoting career development and enhancing mobility of researchers in Europe. This corresponds nicely to one of CERN’s main missions: to train the next generation of scientists and engineers.   The European Commissioner for Education, Culture, Multilingualism, Sport, Media and Youth, Androulla Vassiliou (centre) met the Marie Curie Fellows on her visit to CERN in April 2013. CERN has been pleased to be a major player in the Marie Curie Actions under the Sixth and Seventh Framework Programmes (FP6 from 2002 to 2006 and FP7 from 2007 to 2013), being one of the most successful participants in Europe. Under FP7, CERN was ranked first in Switzerland and fifth in Europe against stiff competition in terms of overall funding. Participation was in all of the Marie Curie Actions: Initial Training Networks, Industry-Academia Partnership Pathways, IRSES, CO...

  16. Golden Girl: Mary Lai Reflects as She Marks Her 50th Anniversary.

    Science.gov (United States)

    Iwanowski, Jay

    1996-01-01

    The career and administrative style of Mary M. Lai, who celebrates her 50th year as chief financial officer at Long Island University (New York), are discussed. Her perspectives on change in higher education and in the institution during that time, the administrator's role, current challenges for financial officers, and the college environment as…

  17. Life as the Middle Child: A Conversation With Mary Margaret Kerr

    Science.gov (United States)

    Teagarden, James M.; Zabel, Robert H.; Kaff, Marilyn S.

    2015-01-01

    As part of an ongoing oral history project, a conversation was held with Dr. Mary Margaret Kerr on the past, present, and possible future of the field of providing services to children with emotional-behavioral disorders. Dr. Wood stresses the increasing importance of providing an interdisciplinary approach to meet the needs for children or, as…

  18. Mari sangari päeva sõnum / Jaak Prozes ; interv. Livia Viitol

    Index Scriptorium Estoniae

    Prozes, Jaak, 1965-

    2006-01-01

    Fenno-Ugria Hõimukeskuse juhataja ja Eestimaa Rahvaste Ühenduse juht soome-ugri rahvaste olukorrast Venemaal ja rahvusseltside tegevusest Eestis. Aprilli lõpul tähistasid marid oma rahvuspüha - mari sangari päeva. Pärimuse põhjal langes maride rahvuskangelane Boltu̧ võitluses oma rahva vabaduse eest 26. aprillil 1556

  19. Marie Underi ühe luuletuse ümber / August Eelmäe

    Index Scriptorium Estoniae

    Eelmäe, August, 1931-

    2003-01-01

    Marie Underi luuletusest "Me ootame" ja selle vaheredaktsioonist, avaldatud pealkirjaga "Üks päev" (Oma Maa, 1947, nr. 2). Ilmunud ka kogumikus: Eelmäe, August. Kõned ja kirjatööd. Tallinn : Underi ja Tuglase Kirjanduskeskus, 2006, lk. 56-71

  20. Late onset axonal Charcot-Marie-Tooth phenotype caused by a novel myelin protein zero mutation

    NARCIS (Netherlands)

    Bienfait, H. M. E.; Faber, C. G.; Baas, F.; Gabreëls-Festen, A. A. W. M.; Koelman, J. H. T. M.; Hoogendijk, J. E.; Verschuuren, J. J.; Wokke, J. H. J.; de Visser, M.

    2006-01-01

    A late onset axonal Charcot-Marie-Tooth phenotype is described, resulting from a novel mutation in the myelin protein zero (MPZ) gene. Comparative computer modelling of the three dimensional structure of the MPZ protein predicts that this mutation does not cause a significant structural change. The

  1. Allied-Signal's Mary Good Analyzes New Threats to Chemical Profession.

    Science.gov (United States)

    Chemical and Engineering News, 1986

    1986-01-01

    Recounts an interview with chemist, educator, and executive Mary Good. Opinions are expressed about the status of basic research in chemistry, the relationship of chemical research to several federal agencies, the value of education in chemistry, and the perceptions of the public regarding the chemical community, particularly the health risks. (TW)

  2. Uned, mida mujal ei näe / Heilika Võsu ; interv. Mari Laaniste

    Index Scriptorium Estoniae

    Võsu, Heilika

    2007-01-01

    PÖFFi animafilmide festivali "Animated Dreams" (21.-25. XI kinos Sõprus), mis on seekord pühendatud Nukufilmi 50. juubelile, tutvustab festivali peakorraldaja. Võistluskavas on Eestist Kaspar Jancise "Maraton" ja Mari-Liis Bassovskaja - Jelena Girlini "Kleit". Lisatud festivali kava

  3. Attracting Talented Researchers to Ireland: A review of The European Marie Curie Programme

    OpenAIRE

    GIORDANI, SILVIA

    2007-01-01

    PUBLISHED The purpose of this publication is to illustrate how researchers in academia and industry in Ireland have successfully secured funding from Europe in the Marie Curie Programme and to highlight the impact this has had in furthering their R&D ambitions.

  4. Sisters in Restaurant Success: A history of The Maramor, Mary Love's Tea Room

    Directory of Open Access Journals (Sweden)

    Jan Whitaker

    2017-02-01

    Full Text Available In 1920, Mary Love opened The Maramor, a tea room style restaurant in Columbus, Ohio that quickly become recognized as one of the country's fine restaurants. Her career is intertwined with the rise of home economics college programs, helping women gain a new-born confidence that was used to dominate the restaurant and catering industry.

  5. Pedagogies and Literacies, Disentangling the Historical Threads: An Interview with Bill Cope and Mary Kalantzis

    Science.gov (United States)

    Cope, Bill; Kalantzis, Mary; Smith, Anna

    2018-01-01

    In this discussion with educational researchers and New London Group conveners, Bill Cope and Mary Kalantzis, we discuss the origins, life, and future of the New London Group's multiliteracies framework. We reflect on the initial goals the group had over 20 years ago for more equitable schooling opportunities, and what is yet to be done to reach…

  6. Hand involvement in children with Charcot-Marie-Tooth disease type 1A

    NARCIS (Netherlands)

    Burns, Joshua; Bray, Paula; Cross, Lauren A.; North, Kathryn N.; Ryan, Monique M.; Ouvrier, Robert A.

    2008-01-01

    Charcot-Marie-Tooth disease type 1A (CMT1A), a demyelinating neuropathy characterised by progressive length-dependent muscle weakness and atrophy, is thought to affect the foot and leg first followed some time later by hand weakness and dysfunction. We aimed to characterise hand Strength, function

  7. Hip Subluxation, first clinical manifestation in a boy with illness of Charcot Marie Tooth

    International Nuclear Information System (INIS)

    Marin Nino, Jorge Enrique; Rosselli Cock, Pablo

    2005-01-01

    Charcot-Marie-Tooth disease is a motor and sensitive neuropathy characterized by limb atrophy and weakness, cavus feet and in some cases acetabular dysplasia. We present a case of bilateral hip subluxation caused by this disease, which needed surgical correction

  8. Effective cauda equina decompression in two siblings with Charcot-Marie-Tooth disease type 1B

    NARCIS (Netherlands)

    van Doormaal, Tristan P C; van Ruissen, Fred; Miller, Kai J; Hoogendijk, Jessica E

    2016-01-01

    Two siblings with Charcot-Marie-Tooth (CMT) 1B due to a c.517G>C (p.Gly173Arg) mutation in the MPZ gene both developed an acute cauda syndrome with unbearable back pain radiating to both legs, progressive muscle weakness of the legs, and saddle hypesthesia with fecal and urinary incontinence. MRI

  9. Charcot-Marie-tooth disease presenting in a young Nigerian male: A ...

    African Journals Online (AJOL)

    Background: Charcot-Marie-Tooth disease is a heterogeneous group of inherited peripheral neuropathy. It has various genetic and phenotypic characteristics and can be a significant cause of morbidity with severe disabling consequences. Often the diagnosis may be missed. It is not commonly encountered in Nigerian ...

  10. Charcot-Marie-Tooth disease due to a de novo mutation of the RAB7 gene

    NARCIS (Netherlands)

    Meggouh, F.; Bienfait, H. M. E.; Weterman, M. A. J.; de Visser, M.; Baas, F.

    2006-01-01

    We report a 32-year-old patient with Charcot-Marie-Tooth (CMT2B) including foot ulcerations. Genetic analysis identified a de novo mutation in the small GTP-ase late endosomal RAB7 gene, consisting of a c.471G>C, p.Lys157Asn missense mutation. This observation strongly supports the hypothesis that

  11. Motor axon loss is associated with hand dysfunction in Charcot-Marie-Tooth disease 1a.

    NARCIS (Netherlands)

    Videler, A.J.; Dijk, J.P. van; Beelen, A.; Visser, M. de; Nollet, F.; Schaik, I.N. van

    2008-01-01

    BACKGROUND: Charcot Marie Tooth type 1a (CMT1a) is a primarily demyelinating neuropathy, characterized by slowly progressive muscle weakness, atrophy, and sensory loss, and is most pronounced in both feet and hands. There is increasing evidence that muscle weakness is determined by motor axonal

  12. Risk of fracture in patients with Charcot-Marie-Tooth disease

    NARCIS (Netherlands)

    Pouwels, Sander; de Boer, Anthonius; Leufkens, Hubert G M; Weber, Wim E J; Cooper, Cyrus; de Vries, Frank

    2014-01-01

    INTRODUCTION: In this study we evaluated fracture risk in patients with Charcot-Marie-Tooth (CMT) disease. METHODS: We conducted a retrospective cohort study using the UK Clinical Practice Research Datalink (1987-2012). Each patient with CMT disease was matched with up to 6 patients without a

  13. Spatially detailed quantification of metal loading for decision making: Metal mass loading to American fork and Mary Ellen Gulch, Utah

    Science.gov (United States)

    Kimball, B.A.; Runkel, R.L.

    2009-01-01

    Effective remediation requires an understanding of the relative contributions of metals from all sources in a catchment, and that understanding must be based on a spatially detailed quantification of metal loading. A traditional approach to quantifying metal loading has been to measure discharge and chemistry at a catchment outlet. This approach can quantify annual loading and the temporal changes in load, but does not provide the needed spatial detail to evaluate specific sources, which is needed to support remediation decisions. A catchment or massloading approach provides spatial detail by combining tracer-injection and synoptic-sampling methods to quantify loading. Examples of studies in American Fork, Utah, and its tributary Mary Ellen Gulch illustrate this different approach. The mass-loading study in American Fork treated Mary Ellen Gulch as a single inflow. From that point of view, Mary Ellen Gulch was one of the greatest sources of Fe, Mn, Zn, and colloidal Pb loads to American Fork. But when Mary Ellen Gulch was evaluated in a separate catchment study, the detailed locations of metal loading were identified, and the extent of metal attenuation upstream from the mouth of Mary Ellen Gulch was quantified. The net, instantaneous load measured at the mouth of Mary Ellen Gulch for remediation planning would greatly underestimate the contributions of principal sources within the catchment. Extending the detailed sampling downstream from Mary Ellen Gulch indicated the possibility of diffuse groundwater inflow from Mary Ellen Gulch to American Fork. Comparing loads for Mary Ellen Gulch in the two studies indicates that metal loads could be substantially underestimated for planning purposes without the detailed catchment approach for the low-flow conditions in these studies. A mass-loading approach provides both the needed quantification of metal loading and the spatial detail to guide remediation decisions that would be the most effective in the catchments

  14. David Bowie and the Art of Slow Innovation: A Fast-Second Winner Strategy for Biotechnology and Precision Medicine Global Development.

    Science.gov (United States)

    Özdemir, Vural; Patrinos, George P

    2017-11-01

    Original ideas and innovation cannot always be ordered like a courier service and delivered fresh to our desk at 9 am. Yet, most creativity-based organizations, careers, and professions, science and biotechnology innovation included, emphasize the speed as the prevailing ideology. But a narrow focus on speed has several and overlooked shortcomings. For example, it does not offer the opportunity to draw from, and stitch together disparate concepts and practices for truly disruptive innovation. Preventing false starts, learning from others' or our own mistakes, and customizing innovations for local community needs are difficult in a speed-hungry innovation ecosystem. We introduce a new strategy, the Fast-Second Winner, specifically in relation to global development of biotechnologies and precision medicine. This à la carte global development strategy envisions a midstream entry into the innovation ecosystem. Moreover, we draw from the works of the late David Bowie who defied rigid classifications as an artist and prolific innovator, and introduce the concept and practice of slow innovation that bodes well with the Fast-Second Winner strategy. A type of slow innovation, the Fast-Second Winner is actually fast and sustainable in the long term, and efficient by reducing false starts in new precision medicine application contexts and geographies, learning from other innovators' failures, and shaping innovations for the local community needs. The establishment of Centers for Fast-Second Innovation (CFSIs), and their funding, for example, by crowdfunding and other innovative mechanisms, could be timely for omics and precision medicine global development. If precision medicine is about tailoring drug treatments and various health interventions to individuals, we suggest to start from tailoring new ideas, and focus not only on how much we innovate but also what and how we innovate. In principle, the Fast-Second Winner can be applied to omics and other biotechnology

  15. A little helps a lot The overall winners of this year's Nursing Standard Nurse of the Year awards have enhanced the lives of hundreds of African children.

    Science.gov (United States)

    Moore, Alison

    2003-11-05

    This year's overall Nurse 2003 award is unusual in that there are two winners, Clare McKenzie and Pauline Stratton. Sadly Ms Stratton receives the award posthumously as she died earlier this year in an accident while visiting the award-winning project in Malawi. The nurses, from the North Cumbria Acute Hospitals NHS Trust, won the Robert Tiffany International award and overall prize for their collaboration with Malawian nurses.

  16. Congregations of the Children of Mary among female students of secondary schools in the Tarnów diocese

    Directory of Open Access Journals (Sweden)

    Edward Kabat

    1996-12-01

    Full Text Available Congregations of the Children of Mary were religious communities inextricably connected with the Sodality of Our Lady. The Sodality came into being through the Society of Jesus. At the request of the Father General Claudius Aquaviva, in 1584 Pope Gregory XIII issued a papal bull "Omnipotens Dei", in which he established the first Sodality of the Blessed Virgin Mary at the Collegio Romano. The Congregation of the Children of Mary was founded in Tarnów at the Ursuline Sisters' establishment (1877, who ran secondary schools until 1939.

  17. Statistical correction of the Winner's Curse explains replication variability in quantitative trait genome-wide association studies.

    Directory of Open Access Journals (Sweden)

    Cameron Palmer

    2017-07-01

    Full Text Available Genome-wide association studies (GWAS have identified hundreds of SNPs responsible for variation in human quantitative traits. However, genome-wide-significant associations often fail to replicate across independent cohorts, in apparent inconsistency with their apparent strong effects in discovery cohorts. This limited success of replication raises pervasive questions about the utility of the GWAS field. We identify all 332 studies of quantitative traits from the NHGRI-EBI GWAS Database with attempted replication. We find that the majority of studies provide insufficient data to evaluate replication rates. The remaining papers replicate significantly worse than expected (p < 10-14, even when adjusting for regression-to-the-mean of effect size between discovery- and replication-cohorts termed the Winner's Curse (p < 10-16. We show this is due in part to misreporting replication cohort-size as a maximum number, rather than per-locus one. In 39 studies accurately reporting per-locus cohort-size for attempted replication of 707 loci in samples with similar ancestry, replication rate matched expectation (predicted 458, observed 457, p = 0.94. In contrast, ancestry differences between replication and discovery (13 studies, 385 loci cause the most highly-powered decile of loci to replicate worse than expected, due to difference in linkage disequilibrium.

  18. Fine-scale ecological and economic assessment of climate change on olive in the Mediterranean Basin reveals winners and losers

    Science.gov (United States)

    Ponti, Luigi; Gutierrez, Andrew Paul; Ruti, Paolo Michele; Dell’Aquila, Alessandro

    2014-01-01

    The Mediterranean Basin is a climate and biodiversity hot spot, and climate change threatens agro-ecosystems such as olive, an ancient drought-tolerant crop of considerable ecological and socioeconomic importance. Climate change will impact the interactions of olive and the obligate olive fruit fly (Bactrocera oleae), and alter the economics of olive culture across the Basin. We estimate the effects of climate change on the dynamics and interaction of olive and the fly using physiologically based demographic models in a geographic information system context as driven by daily climate change scenario weather. A regional climate model that includes fine-scale representation of the effects of topography and the influence of the Mediterranean Sea on regional climate was used to scale the global climate data. The system model for olive/olive fly was used as the production function in our economic analysis, replacing the commonly used production-damage control function. Climate warming will affect olive yield and fly infestation levels across the Basin, resulting in economic winners and losers at the local and regional scales. At the local scale, profitability of small olive farms in many marginal areas of Europe and elsewhere in the Basin will decrease, leading to increased abandonment. These marginal farms are critical to conserving soil, maintaining biodiversity, and reducing fire risk in these areas. Our fine-scale bioeconomic approach provides a realistic prototype for assessing climate change impacts in other Mediterranean agro-ecosystems facing extant and new invasive pests. PMID:24706833

  19. Fine-scale ecological and economic assessment of climate change on olive in the Mediterranean Basin reveals winners and losers.

    Science.gov (United States)

    Ponti, Luigi; Gutierrez, Andrew Paul; Ruti, Paolo Michele; Dell'Aquila, Alessandro

    2014-04-15

    The Mediterranean Basin is a climate and biodiversity hot spot, and climate change threatens agro-ecosystems such as olive, an ancient drought-tolerant crop of considerable ecological and socioeconomic importance. Climate change will impact the interactions of olive and the obligate olive fruit fly (Bactrocera oleae), and alter the economics of olive culture across the Basin. We estimate the effects of climate change on the dynamics and interaction of olive and the fly using physiologically based demographic models in a geographic information system context as driven by daily climate change scenario weather. A regional climate model that includes fine-scale representation of the effects of topography and the influence of the Mediterranean Sea on regional climate was used to scale the global climate data. The system model for olive/olive fly was used as the production function in our economic analysis, replacing the commonly used production-damage control function. Climate warming will affect olive yield and fly infestation levels across the Basin, resulting in economic winners and losers at the local and regional scales. At the local scale, profitability of small olive farms in many marginal areas of Europe and elsewhere in the Basin will decrease, leading to increased abandonment. These marginal farms are critical to conserving soil, maintaining biodiversity, and reducing fire risk in these areas. Our fine-scale bioeconomic approach provides a realistic prototype for assessing climate change impacts in other Mediterranean agro-ecosystems facing extant and new invasive pests.

  20. ALS5/SPG11/KIAA1840 mutations cause autosomal recessive axonal Charcot-Marie-Tooth disease.

    Science.gov (United States)

    Montecchiani, Celeste; Pedace, Lucia; Lo Giudice, Temistocle; Casella, Antonella; Mearini, Marzia; Gaudiello, Fabrizio; Pedroso, José L; Terracciano, Chiara; Caltagirone, Carlo; Massa, Roberto; St George-Hyslop, Peter H; Barsottini, Orlando G P; Kawarai, Toshitaka; Orlacchio, Antonio

    2016-01-01

    Charcot-Marie-Tooth disease is a group of hereditary peripheral neuropathies that share clinical characteristics of progressive distal muscle weakness and atrophy, foot deformities, distal sensory loss, as well as diminished tendon reflexes. Hundreds of causative DNA changes have been found, but much of the genetic basis of the disease is still unexplained. Mutations in the ALS5/SPG11/KIAA1840 gene are a frequent cause of autosomal recessive hereditary spastic paraplegia with thin corpus callosum and peripheral axonal neuropathy, and account for ∼ 40% of autosomal recessive juvenile amyotrophic lateral sclerosis. The overlap of axonal Charcot-Marie-Tooth disease with both diseases, as well as the common autosomal recessive inheritance pattern of thin corpus callosum and axonal Charcot-Marie-Tooth disease in three related patients, prompted us to analyse the ALS5/SPG11/KIAA1840 gene in affected individuals with autosomal recessive axonal Charcot-Marie-Tooth disease. We investigated 28 unrelated families with autosomal recessive axonal Charcot-Marie-Tooth disease defined by clinical, electrophysiological, as well as pathological evaluation. Besides, we screened for all the known genes related to axonal autosomal recessive Charcot-Marie-Tooth disease (CMT2A2/HMSN2A2/MFN2, CMT2B1/LMNA, CMT2B2/MED25, CMT2B5/NEFL, ARCMT2F/dHMN2B/HSPB1, CMT2K/GDAP1, CMT2P/LRSAM1, CMT2R/TRIM2, CMT2S/IGHMBP2, CMT2T/HSJ1, CMTRID/COX6A1, ARAN-NM/HINT and GAN/GAN), for the genes related to autosomal recessive hereditary spastic paraplegia with thin corpus callosum and axonal peripheral neuropathy (SPG7/PGN, SPG15/ZFYVE26, SPG21/ACP33, SPG35/FA2H, SPG46/GBA2, SPG55/C12orf65 and SPG56/CYP2U1), as well as for the causative gene of peripheral neuropathy with or without agenesis of the corpus callosum (SLC12A6). Mitochondrial disorders related to Charcot-Marie-Tooth disease type 2 were also excluded by sequencing POLG and TYMP genes. An additional locus for autosomal recessive Charcot-Marie

  1. Environmental review of the Mary Kathleen uranium minesite, Northwest Queensland

    International Nuclear Information System (INIS)

    Costelloe, M.T.; Lottermoser, B.G.; Ashley, P.M.

    1999-01-01

    Full text: The Mary Kathleen uranium deposit, in northwest Queensland, was discovered in 1954 and mined in 19561963 and 1976-1982. Rehabilitation of the site was completed in 1985 and the work won an award for environmental excellence. In 1999 gamma-ray data, plus stream sediment, soil, rock chip, mineral efflorescence, vegetation and water samples were collected from selected sites to assist in the examination of the current environmental status of the rehabilitated area. This paper presents preliminary results and interpretations. In the Mark Kathleen open pit, skarn type U-Th-REE mineralisation is hosted in amphibolite grade metamorphosed calc-silicate, mafic to intermediate igneous and sedimentary rocks. Remnant ore zones are composed of medium to coarse grained garnet and clinopyroxene, with accessory allanite, plagioclase, pyrrhotite, chalcopyrite and uraninite. Later retrograde alteration to chlorite, calcite, sericite, epidote and scapolite occurs. Fine grained uraninite is enclosed in allanite, and is partly replaced by metamict products nd traces of galena. Elevated gamma-ray readings in the open pit correspond to exposed ore lenses, the former haul road and abandoned ore stockpiles (up to 16 mSv/year). Surficial oxidation of ore and adjacent sulphide-bearing calc-silicate rocks has led to contemporary precipitation of yellow, orange, green and white mineral efflorescences on the pit walls. Wallrock oxidation of reactive sulphides (mainly pyrrhotite breakdown) produces acidic solutions, however, buffering reactions of these fluids with gangue calc-silicates and carbonate phases prevent low pH conditions from developing. The open pit lake is approximately 40m deep and contains saline (0.15%) surface waters which are Ca-, SO 4 -rich with elevated Cu, Fe, Mn, Ni, U and Zn at a pH of 6.11. Waste rock piles are up to 30m thick and have been covered by a thin veneer of benign waste. However, there are high radiation levels on several waste rock piles (up to 20

  2. Identificação diferencial de Rhodococcus equi e Dietzia maris em bubalinos Differential identification of Rhodococcus equi and Dietzia maris in buffaloes

    Directory of Open Access Journals (Sweden)

    L.R. Viana

    2009-08-01

    Full Text Available Foram analisados 24 isolados bacterianos oriundos de leite e pele de búfalas (Bubalus bubalis, os quais foram previamente identificados como Rhodococcus equi com o auxílio de fenotipia concisa. Testes fenotípicos complementares e ferramentas moleculares foram utilizados com o objetivo de caracterizar esses isolados, bem como diferenciá-los de outros microrganismos intimamente relacionados. Observaram-se três fenótipos distintos, porém a identificação dos isolados foi inconclusiva. Apenas um dos isolados foi comprovado como sendo R. equi com a realização da PCR espécie-específica, sequenciamento e análise dos fragmentos de DNA. Os demais isolados só foram identificados pelo sequenciamento de fragmento do gene que codifica a região 16S do rRNA universal de bactérias, indicando tratar-se de Dietzia maris. O perfil de susceptibilidade aos antimicrobianos revelou maior resistência dos isolados de D. maris para oxacilina (96% e rifampicina (87%. O isolado de R. equi apresentou resistência à amicacina, oxacilina, penicilina, rifampicina e tetraciclina. Alerta-se para o risco da incorreta identificação dos isolados baseados em testes fenotípicos concisos e para a necessidade de utilização de testes complementares para diferenciação entre R. equi e D. maris.Twenty-four bacterial isolates from milk and skin of buffalo females (Bubalus bubalis, which previously had been identified as Rhodococcus equi by using a restricted number of phenotypical tests for bacterial characterization, were analyzed. The goal of this study was to perform the characterization of these isolates, as well as the differentiation of other microorganisms closely related by using additional phenotypical tests and molecular tools. Based on the phenotypical results, three different biotypes were obtained. However, the identification of the isolates was inconclusive. Only one of the isolates was confirmed as R. equi by the PCR specifically for this species, as

  3. Marcel Mariën’s 'Woman Ajar'. A case of minor photography?

    Directory of Open Access Journals (Sweden)

    Mieke Bleyen

    2010-12-01

    Full Text Available

     

    Abstract (E: This paper examines Woman Ajar (1985, a late, largely forgotten photo book by Marcel Mariën, one of the key figures of Belgian post war surrealism. Representing the female body as fragmented and alienated by small objects, Mariën’s photographs balance between the private (amateurish and the public (professional and explores the fragile border between art and pornography. In addition, there is a sense of belatedness in them, which makes them particularly hard to label. This paper proposes the concept of minor photography, borrowed from Gilles Deleuze and Felix Guattari’s concept of a minor literature, as a valuable tool to approach Marcel Mariën’s work, which risks slipping through art history’s net.

    Abstract (F: Cet article examine Woman Ajar (1985, un livre de photographie tardif et largement oublié de Marcel Mariën, l’une des figures clés du surréalisme belge d’après-guerre. Représentant le corps féminin comme fragmenté et aliéné par de petits objets, les photographies de Mariën balancent entre les sphères privée (amateur et publique (professionnelle et explorent la frontière fragile entre l’art et la pornographie. En outre, il y a en elles un sens de la tardiveté, qui les rend particulièrement difficiles à étiqueter. Cet article propose le concept de photographie mineure, emprunté au concept de littérature mineure avancé par Gilles Deleuze et Félix Guattari, comme un outil précieux permettant d’approcher l’œuvre de Marcel Mariën, qui court le risque de glisser au travers du filet de l’histoire de l’art.

  4. Entretiens avec Marie Raynal, Redactrice em chef de Diversitè - France. Interview with Marie Raynal, editor of Diversité - France

    Directory of Open Access Journals (Sweden)

    Abramowicz, Anete

    2009-11-01

    Full Text Available A Revista Eletrônica de Educação teve o privilégio de entrevistar Marie Raynal, que apesar de muitas atividades nos concedeu um tempo para nos responder. Marie Raynal é Responsável pelo Departamento Ville-Ecole-Intégration (Cidade-Escola-Integração em Montrouge, França e Redatora Chefe (rédactrice em chef da Revista Diversité que é um dos únicos periódicos da educação na França que acolhe artigos sobre a diversidade social. Em 2003 foi criado o departamento “Ville & Education” sob a coordenação de Marie Raynal. Este departamento tem por missão acompanhar todos os atores da educação (professores, quadros da educação, coletividades, associações, etc. que tem por encargo - durante e fora do tempo escolar - as crianças e os jovens em situação de fragilidade, especialmente aqueles que vivem nos bairros da política da cidade, àqueles que se destacam por uma educação prioritária, os recém chegados na França e as crianças nômades. No conjunto destas questões, este departamento é considerado como expert nacional. Este departamento possui três revistas e uma carta de informação, entre elas está a revista trimestral em Ciências Sociais, a Diversité.The Revista Eletrônica de Educação (Electronic Journal of Education has the privilege to interview Marie Raynal, which although having many activities, dedicated us time to answer it. Marie Raynal is head of the Département de Ville-Ecole-Intégration (Department of City-School-Integration in Montrouge, France and Chief editor of the journal Diversité, which includes articles on social diversity. In 2003, the department "Ville & Education" is created under the authority of Marie Raynal. Its mission is to accompany all education members (teachers, education managers, communities, associations, etc. that are in charge, during and after school time, children and youth in situations of fragility, including those living in neighborhood of the city policy, those

  5. Pahede koht on ajaloo prügikastis! Kas ikka on? / Andres Maimik, Maris Jesse ; intervjueerinud Sigrid Kõiv

    Index Scriptorium Estoniae

    Maimik, Andres, 1970-

    2009-01-01

    Proua Evelin Ilves tegi ettepaneku, et arstid võiksid inimesi innustada isikliku eeskujuga ja viia ennast tervislikku vormi. Filmimees Andres Maimik ja terviseedendaja Maris Jesse arutavad, kas on võimalik pahelisi eluviise välja juurida

  6. Mida arvatakse omavalitsustes koolivõrgu optimeerimisest? / Mart Järvik, Maris Liiders, Peeter Aas, Kaarin Veinbergs

    Index Scriptorium Estoniae

    2012-01-01

    Arvamust avaldasid Järvakandi vallavanem, Raplamaa omavalitsuste liidu esimees Mart Järvik, Harju maavalitsuse haridus- ja sotsiaalosakonna juhataja Maris Liiders, Põlva maavalitsuse haridus- ja sotsiaalosakonna juhataja Peeter Aas, Ida-Viru maavalitsuse haridus- ja sotsiaalosakonna juhataja Kaarin Veinbergs

  7. [Mari Uusküla. Basic colour terms in Finno-Ugric and Slavonic Languages] / Galina Paramei

    Index Scriptorium Estoniae

    Paramei, Galina

    2010-01-01

    Arvustus: Uusküla, Mari. Basic colour terms in Finno-ugric and Slavonic languages: myths and facts. Tartu : Tartu University Press, 2008. Dissertationes linguisticae Universitatis Tartuensis, 1406-5657 ; 9

  8. Mirzam C. Pérez, The Comedia of Virginity: Mary and the Politics of Seventeenth-Century Spanish Theater

    Directory of Open Access Journals (Sweden)

    Natalia Fernández

    2016-01-01

    Full Text Available Reseña de Mirzam C. Pérez, The Comedia of Virginity: Mary and the Politics of Seventeenth-Century Spanish Theater, Waco (Texas, Baylor University Press, 2012, 173 pp. ISBN: 9781602586451.

  9. Armastus kui vale(m) : Mari Vihmandi ooperi "Armastuse valem" lavastusest Estonias / Ester Võsu ja Kristel Pappel

    Index Scriptorium Estoniae

    Võsu, Ester, 1975-

    2009-01-01

    Argentiina kirjaniku Esther Vilari romaani "Nina Glucksteini matemaatika" ainetel valminud Mari Vihmandi ooperist "Armastuse valem", libreto Maimu Berg, lavastaja Liis Kolle, tantsu- ja liikumisseaded Ana Mondini. Esietendus 17. oktoobril 2008 Rahvusooperis Estonia

  10. Mitochondrial DNA analysis on remains of a putative son of Louis XVI, King of France and Marie-Antoinette.

    Science.gov (United States)

    Jehaes, E; Decorte, R; Peneau, A; Petrie, J H; Boiry, P A; Gilissen, A; Moisan, J P; Van den Berghe, H; Pascal, O; Cassiman, J J

    1998-01-01

    Carl Wilhelm Naundorff was buried in 1845 in Delft as Louis Charles, Duc de Normandie, 'Louis XVII'. However, the son of Louis XVI and Marie-Antoinette-Louis XVII--officially died in the Temple of Paris in 1795. In order to resolve the identity of Naundorff, mitochondrial DNA (mtDNA) D-loop sequences of his remains were compared with the sequences obtained from the hairs of two sisters of Marie-Antoinette, Marie-Antoinette herself, and with the sequences obtained from DNA samples of two living maternal relatives. The mtDNA sequence of a bone sample from Naundorff showed two nucleotide differences from the sequences of the three sisters and four differences from the sequences of living maternal relatives. Based on this evidence it becomes very unlikely that Naundroff is the son of Marie-Antoinette.

  11. Joep van Gennip, Vefie Poels en Marie-Antoinette Willemsen (eds., Creatie en recreatie. Cultuur en ontspanning in het kloosterleven

    Directory of Open Access Journals (Sweden)

    Thomas Quartier

    2017-06-01

    Full Text Available Joep van Gennip, Vefie Poels en Marie-Antoinette Willemsen (eds., Creatie en recreatie. Cultuur en ontspanning in het kloosterleven (Hilversum: Verloren, 2014, 234 pp., isbn 978 908 704 469 5.

  12. [Mari Laanemets. Zwischen westlicher Moderne und sowjetischer Avantgarde. Inofizielle Kunst in Estland 1969-1978] / Mara Traumane

    Index Scriptorium Estoniae

    Traumane, Mara

    2013-01-01

    Arvustus: Laanemets, Mari. Zwischen westlicher Moderne und sowjetischer Avantgarde. Inofizielle Kunst in Estland 1969-1978. (Humboldt-Schriften zur Kunst- und Bildgeschichte, Bd. 14.9 Berlin: Gebr. Mann 2011

  13. Controversial Questions of the Early Neolithic Studies in the Mari Volga Region

    Directory of Open Access Journals (Sweden)

    Vybornov A.A.

    2017-03-01

    Full Text Available The article considers some debatable questions of cultural identity, origin and correlation between the different Neolithic sites in the territory of the Mari Volga region, located at the junction of forest-steppe Volga River, Sura River and Lower Kama areas as well as the Upper Volga. The Early Neolithic of this region is characterized by presence of pottery without ornamentation and stroke ware. In the Late Neolithic, the sites with the pottery of Kama culture and of pit-comb type were spread there. The author suggests his own version of development of Neolithic cultures in this region, based on typological approaches and the results of radiocarbon dating and technological analysis of the pottery. Spread of ware without ornamentation seems to be preceding the stroke ware, and both traditions in the Mari land were under the cultural impact of the forest-steppe Volga population.

  14. The ties that bind: Soil surveyor William Edgar Tharp and oceanographic cartographer Marie Tharp

    Science.gov (United States)

    Landa, Edward R.

    The link between soil science and geology is personified in the American father and daughter: soil surveyor William Edgar Tharp (1870-1959) and oceanographic cartographer Marie Tharp (1920-2006). From 1904 to 1935, W.E. Tharp mapped soils in 14 states for the US Department of Agriculture, and campaigned during the late 1920s-early 1930s to raise awareness of the high rates of soil erosion from croplands. The lifestyle of the federal soil surveyor in the United States during the early 20th century involved frequent household moves, and it played a formative role in Marie Tharp’s childhood. Her path to a career in geology was molded by this family experience, by mentors encountered in the classroom, and by social barriers that faced women scientists of that era.

  15. I Want to Believe: A Short Psychobiography of Mary Baker Eddy.

    Science.gov (United States)

    Dean, Taylor Wilson

    2016-01-01

    The 18th and 19th centuries were beset with new religious movements in the United States: Shakers, Latter Day Saints, Millerites, and Seventh Day Adventists to name a few. One group, Christian Science, held radically different views than their counterparts and their origins lay in the most unlikely of places, a perpetually ill and poor woman from New Hampshire. Much has been said about Mary Baker Eddy: some say that she was a prophet, others that she was a fraud. Herein no such judgments are made. This study seeks to look into the life of Mary Baker Eddy from a psychological lens in the hopes that insight can be gained into the founding of the First Church of Jesus Christ Scientist and perhaps to allay the binary of Mrs. Eddy as either prophet or fanatic.

  16. Flower Power: Desire, Gender, and Folk Belief in the Joycean Mary Garden

    Directory of Open Access Journals (Sweden)

    Christin Mulligan

    2017-06-01

    Full Text Available Robert Brazeau and Derek Gladwin’s Eco-Joyce (2014 largely overlooks a historical basis for ecocritical thought. The absence of a historicist view requires consideration not only of the natural world but folk botany, such as the Mary Garden that is a phantom presence in A Portrait of the Artist as a Young Man as well as in “Nausicaa” and “Penelope” in Ulysses and Finnegans Wake. The undergrowth of the garden reconfigures human action and subtly predicts it with its compendium of theological and devotional meanings for the burgeoning sexuality expressed by Gerty MacDowell and Issy Earwicker as well as the mature longing of Molly Bloom. This essay will establish a fresh Deleuzian paradigm of Becoming-Flower to demonstrate how the Mary Garden blooms to present new perspectives on Catholicism, eros, and gender identity in Joyce’s major works.

  17. Mining Cultures and Mary Cults: Where the Sacred and Profane Meet.

    Science.gov (United States)

    Munday, Pat

    2016-01-01

    Our Lady of the Rockies (OLR) is a ninety-foot-tall statue of the Virgin Mary overlooking Butte, Montana, from its perch high atop the Continental Divide. In the popularized account, OLR is a uniquely local undertaking reflecting the community's character and pride. Yet OLR is far more than this, for it taps into a rich vein of cultural and spiritual tradition. As Mircea Eliade pointed out, the notion of the earth as female pervaded early Western civilizations. Mines were like the vagina of the earth, leading to the womb where metallic ores waxed like embryos. Accordingly, miners purified themselves through various rites to amend their violation. OLR began as a plan for a small, private altar. With the collapse of Butte's copper mining economy, unemployed miners rallied around the idea of building a major shrine to the Virgin Mary that would help restore the city's culture and economy.

  18. Charcot-Marie-Tooth disease masquerading as acute demyelinating encephalomyelitis-like illness.

    Science.gov (United States)

    Kim, Gun-Ha; Kim, Kyoung Min; Suh, Sang-Il; Ki, Chang-Seok; Eun, Baik-Lin

    2014-07-01

    X-linked Charcot-Marie-Tooth disease (CMTX1) is a clinically heterogeneous hereditary motor and sensory neuropathy with X-linked transmission. Common clinical manifestations of CMTX1 disease, as in other forms of Charcot-Marie-Tooth (CMT) disease, are distal muscle wasting and weakness, hyporeflexia, distal sensory disturbance, and foot deformities. Mutations in the connexin-32 gene (gap junction protein β1 [GJB1]) are responsible for CMTX1 disease. In this report, we describe a patient with CMTX1 disease presenting with recurrent attacks of transient and episodic acute demyelinating encephalomyelitis (ADEM)-like symptoms without previous signs of lower extremity weakness or foot deformities; the patient, as well as his asymptomatic mother, exhibited a novel GJB1 mutation (p.Met1Ile). Differential diagnosis of recurrent and transient ADEM-like illness, if unexplained, should include the possibility of CMTX1 disease. Copyright © 2014 by the American Academy of Pediatrics.

  19. Umbilical metastasis (Sister Mary Joseph's nodule diagnosed by fine-needle aspiration

    Directory of Open Access Journals (Sweden)

    Tatomirović Željka

    2004-01-01

    Full Text Available Sister Mary Joseph’s nodule is the eponym for metastatic involvement of the umbilicus. This less common entity is the sign of disseminated malignant disease, mainly of digestive and gynecologic origin, and is associated with a poor prognosis. A case of Sister Mary Joseph’s nodule in a 76-year-old woman in whom the umbilical metastasis was the first sign of malignant disease in presented. The diagnosis of metastatic adenocarcinoma was established by fine needle aspiration cytology of the umbilical nodule. Radiological and ultrasonographic investigation disclosed carcinoma of the gallbladder with pancreas, stomach, and colon invasion as well as peritoneal dissemination. The diagnosis was confirmed by exploratory laparatomy and histological examination of the excised umbilical nodule.

  20. De Novo duplication in Charcot-Marie-Tooth Type 1A

    Energy Technology Data Exchange (ETDEWEB)

    Mandich, P.; Bellone, E.; Ajmar, F. [and others

    1996-09-01

    We read with interest the paper on {open_quotes}Prevalence and Origin of De Novo Duplications in Charcot-Marie-Tooth Disease Type 1A: First Report of a De Novo Duplication with a Maternal Origin,{close_quotes}. They reported their experience with 10 sporadic cases of Charcot-Marie-Tooth type 1A (CMT1A) in which it was demonstrated that the disease had arisen as the result of a de novo duplication. They analyzed the de novo-duplication families by using microsatellite markers and identified the parental origin of the duplication in eight cases. In one family the duplication was of maternal origin, whereas in the remaining seven cases it was of paternal origin. The authors concluded that their report was the first evidence of a de novo duplication of maternal origin, suggesting that this is not a phenomenon associated solely with male meiosis. 7 refs.

  1. [Marie Curie, née Maria Sklodowska (1867-1934)--contribution to the development of radiology].

    Science.gov (United States)

    Babić, Rade R; Babić, Gordana Stanković

    2011-01-01

    Marie Curie, née Maria Sklodowska, was born on November 7, 1867 in Warsaw (Poland). She suffered from leukaemia and died on June 4, 1934. She was buried with full honours at Pantheon. Marie Curie and her husband Pierre Curie discovered the radioactive elements Polonium (84Po210), Thorium (90Th232) and Radium (88Ra226). Marie Curie introduced the term radioactivity into science. She was the first woman who got Ph.D. in France, the first woman professor at Sorbonne, Paris and Medical Academy. Of all the women who have ever won the Nobel Prize, Marie Curie was the only who received it twice. During World War I Marie Curie designed a mobile x-ray room "radiologic car". Marie Curie had an x-ray machine installed into a car and demonstrated how to use its dynamo for electric power production necessary for the x-ray machine to work. She had 20 cars with moving radiological lab made and trained 150 people to work on them. She brought something radically new into military medicine--mobile x-ray diagnostics. With the discovery of radioactive elements a new medical branch, radiotherapy, was developed.

  2. Un conflicto matrimonial en el siglo XVIII: Henri de Vaucocour y Marie Boutinaud

    Directory of Open Access Journals (Sweden)

    Stéphane Minvielle

    2013-12-01

    Full Text Available El matrimonio en 1741 de dos miembros de la baja nobleza del suroeste de Francia, Henri de Vaucocour y Marie Boutinaud, desembocó, a partir de 1751, en un proceso judicial de separación. Los fondos documentales conservados sirven para analizar un conflicto matrimonial, las relaciones entre esposos, y las múltiples facetas de la violencia doméstica en la Francia del siglo XVIII

  3. Mary Wollstonecraft Shelley's Frankenstein, or the modern Prometheus: a psychological study of unrepaired shame.

    Science.gov (United States)

    Severino, Sally K; Morrison, Nancy K

    2013-01-01

    Mary Wollstonecraft Shelley's modern Prometheus shows us the eternal punishment of unrepaired shame--eternal entrapment within the shame triangle of victim, perpetrator and rescuer. This paper describes how Shelley's insight--that lack of love creates a monster living in shame--is being confirmed by neuroscience and how this is exemplified in two characters--the creature and Victor Frankenstein. Additionally, it delineates how pastoral counselors can help those suffering from unrepaired shame

  4. Rapports 2017-2018 sur les frais de voyage pour Mary Anne ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Chantal Taylor

    Billet d'avion. 368.41 $. Frais de transport au sol ou autrement. 69.95 $. Frais de logement. 542.79 $. Repas et frais divers. 164.42 $. Autre frais. 0.00 $. Total. 1 145.57 $. Commentaires. À partir de sa résidence à Thornhill, Ontario. Rapports 2017-2018 sur les frais de voyage pour. Mary Anne Chambers, gouverneur, ...

  5. Reversing Eve’s curse: Mary Magdalene Pilgrims and the creative ritualization of menstruation

    OpenAIRE

    Fedele, A.

    2014-01-01

    This article is about the creative ritual practices of a group of Spanish and Catalan pilgrims who visit French shrines dedicated to Saint Mary Magdalene. Raised and educated in Catholic families, these women describe themselves as being part of the worldwide Goddess movement and do not consider their theories and rituals to be in conflict with Christian values. During their pilgrimages they celebrate rituals in shrines that they feel were unjustly monopolized by the “Church”. The pilgrims se...

  6. Rapport de frais de 2017-2018 pour Mary Anne Chambers | CRDI ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Rapport de frais de 2017-2018 pour Mary Anne Chambers. Total des frais de déplacement : CAD$17,362.55. Réunion du Conseil des gouverneurs. 19 novembre 2017 au 24 novembre 2017. CAD$2,185.41. Réunions au CRDI 1 novembre 2017 CAD$714.15. Constatation de l'impact de la recherche en Afrique de l'Est.

  7. The persuasive power of a mother's breast: the most desperate act of the Virgin Mary's Advocacy

    OpenAIRE

    Ryan, Salvador

    2002-01-01

    Depictions of the Madonna and Child, which for centuries have adorned Catholic churches and burial grounds, tend to evoke warm responses from the majority who choose to behold what appears to be an idyllic and peaceful scene. A variation of this theme, such as the portrayal of the Virgin Mary breast-feeding her Divine Son, although less common, has also claimed great popularity among iconographers from the first centuries of Christianity. However, some popular late-medieval interpretations of...

  8. Maria Carolina and Marie Antoinette: Sisters and Queens in the mirror of Jacobin Public Opinion

    Directory of Open Access Journals (Sweden)

    Cinzia Recca

    2014-09-01

    Full Text Available Marie Antoinette of Franceand Maria Carolina of Naples, both consorts, contributed to a flourishing of matronage, reproducing conceptions of royal femininity that embraced both the private and public roles they were expected to fulfil. However, while the political role of the first Queen has been largely reconsidered, her sister Maria Carolina has not yet been adjudicated impartially. This is somewhat curious, because Maria Carolina inherited from her sister the same disregard towards the Revolution and this, as perceived by the Jacobins, was duly proposed in their acrimonious criticism of her political role. This paper aims to focus on this criticism, analysing how the charges against Maria Carolina in the post-French revolutionary period, were a political duplication of the Jacobin attacks on Marie Antoinette from 1791 onwards. From this point of view, the paper will focus on the portrait of Maria Carolina in 1793 revolutionary Parisby Giuseppe Gorani, an Italian Jacobin noble. His Mémoires Secrets – where Maria Carolina was represented as a wicked woman in the same terms previously employed to denounce her sister Marie Antoinette by the French Republicans – was well known across Italy. This subject dominated the main pamphlets and brochures published in Naples in 1799, during the brief duration of the Neapolitan Republic, because it legitimised the rebellion against the monarchy. After the fall of the Neapolitan Republic, the political attacks on Maria Carolina continued likewise in France, where many Neapolitan patriots were obliged to flee. Analysing  Giuseppe Gorani’s Mémoires we gather that the portrait of Marie Antoinette’s sister was painted according to the main stereotypes of  French revolutionary political culture.

  9. The Historical Threshold : Crisis, Ritual and Liminality in Sofia Coppola’s Marie-Antoinette (2006

    Directory of Open Access Journals (Sweden)

    Anna Backman Rogers

    2012-10-01

    Full Text Available Marie Antoinette does not pertain to any of the narrative tropes and standards set by the conventional historical drama. Rather, it is a film about the politicisation of the female body. Its focus on the rite of passage of a young girl into adulthood in an extreme situation is, in effect, highly political both in its effort to convey a specifically female subjectivity and in its eschewal of a more traditional treatment of its subject matter.

  10. The Historical Threshold : Crisis, Ritual and Liminality in Sofia Coppola’s Marie-Antoinette (2006)

    OpenAIRE

    Anna Backman Rogers

    2012-01-01

    Marie Antoinette does not pertain to any of the narrative tropes and standards set by the conventional historical drama. Rather, it is a film about the politicisation of the female body. Its focus on the rite of passage of a young girl into adulthood in an extreme situation is, in effect, highly political both in its effort to convey a specifically female subjectivity and in its eschewal of a more traditional treatment of its subject matter.

  11. Feeling vs vorm. White label : Under Marie. Kuula / DJ Pickney Tiger

    Index Scriptorium Estoniae

    DJ Pickney Tiger, pseud., 1970-

    2007-01-01

    Rockansambli Chungin and the Strap-On-Faggots ja soome punkbändi Rejects kontserdist Tallinnas Reggae Baaris. Heliplaadist: Under Marie "1. What What? 2. What What?". Heliplaatidest: Zahir "Green means go", Ry Cooder "My name is Buddy", Ladysmith Black Mambazo "Warner Bros. Collection", Macy Gray "Big", Nneka "Victim of Truth", "Grinderman", Stooges "The Weirdness", "The Good, The Bad and the Queen", Marco Di Marco "In New York, My Poetry", Kaiser Chiefs "Yours Truly, Angry Mob", Mika "Life in cartoon motion"

  12. HDAC6 is a therapeutic target in mutant GARS-induced Charcot-Marie-Tooth disease.

    Science.gov (United States)

    Benoy, Veronick; Van Helleputte, Lawrence; Prior, Robert; d'Ydewalle, Constantin; Haeck, Wanda; Geens, Natasja; Scheveneels, Wendy; Schevenels, Begga; Cader, M Zameel; Talbot, Kevin; Kozikowski, Alan P; Vanden Berghe, Pieter; Van Damme, Philip; Robberecht, Wim; Van Den Bosch, Ludo

    2018-02-05

    Peripheral nerve axons require a well-organized axonal microtubule network for efficient transport to ensure the constant crosstalk between soma and synapse. Mutations in more than 80 different genes cause Charcot-Marie-Tooth disease, which is the most common inherited disorder affecting peripheral nerves. This genetic heterogeneity has hampered the development of therapeutics for Charcot-Marie-Tooth disease. The aim of this study was to explore whether histone deacetylase 6 (HDAC6) can serve as a therapeutic target focusing on the mutant glycyl-tRNA synthetase (GlyRS/GARS)-induced peripheral neuropathy. Peripheral nerves and dorsal root ganglia from the C201R mutant Gars mouse model showed reduced acetylated α-tubulin levels. In primary dorsal root ganglion neurons, mutant GlyRS affected neurite length and disrupted normal mitochondrial transport. We demonstrated that GlyRS co-immunoprecipitated with HDAC6 and that this interaction was blocked by tubastatin A, a selective inhibitor of the deacetylating function of HDAC6. Moreover, HDAC6 inhibition restored mitochondrial axonal transport in mutant GlyRS-expressing neurons. Systemic delivery of a specific HDAC6 inhibitor increased α-tubulin acetylation in peripheral nerves and partially restored nerve conduction and motor behaviour in mutant Gars mice. Our study demonstrates that α-tubulin deacetylation and disrupted axonal transport may represent a common pathogenic mechanism underlying Charcot-Marie-Tooth disease and it broadens the therapeutic potential of selective HDAC6 inhibition to other genetic forms of axonal Charcot-Marie-Tooth disease. © The Author(s) (2018). Published by Oxford University Press on behalf of the Guarantors of Brain.

  13. Refined genetic mapping of X-linked Charcot-Marie-Tooth neuropathy

    Energy Technology Data Exchange (ETDEWEB)

    Fain, P.R.; Barker, D.F.; Chance, P.F. (Univ. of Utah, School of Medicine, Salt Lake City, UT (United States))

    1994-02-01

    Genetic linkage studies were conducted in four multigenerational families with X-linked Charcot-Marie-Tooth disease (CMTX), using 12 highly polymorphic short-tandem-repeat markers for the pericentromeric region of the X Chromosome. Pairwise linkage analysis with individual markers confirmed tight linkage of CMTX to the pericentromeric region in each family. Multipoint analyses strongly support the order DXS337-CMTX-DXS441-(DXS56, PGK1). 38 refs., 2 figs., 1 tab.

  14. Charcot-Marie-Tooth disease and posterior scleritis: a case report Doença de Charcot-Marie-Tooth e esclerite posterior: relato de caso

    Directory of Open Access Journals (Sweden)

    Elisabeth N. Martins

    2000-10-01

    Full Text Available Purpose: To describe the unusual association of Charcot-Marie-Tooth disease (CMTD and posterior scleritis. Methods: Case report of a 16-year-old female with decreased visual acuity and pain in both eyes. Results: Ophthalmologic examination showed a posterior scleritis, confirmed by ultrasound and angiofluoresceinography. Foot deformities and sensory dysfunction were identified in the patient and some of her relatives. The diagnosis of CMTD in this patient was confirmed by eletrophysiologic studies. Conclusions: The association of posterior scleritis in a patient with CMTD has never been reported. This is also the first description of an inflammatory ocular disease in these patients.Objetivo: Descrever a associação entre doença de Charcot-Marie-Tooth (DCMT e esclerite posterior. Metodologia: Relato de caso de uma paciente do sexo feminino, 16 anos de idade, com baixa de acuidade visual e dor em ambos os olhos. Resultados: O exame oftalmológico revelou esclerite posterior, observada também por ultra-som e angiofluoresceinografia. Deformidades de pernas e pés foram identificadas na paciente e em seus familiares. O diagnóstico de DCMT na paciente estudada foi confirmado por estudos eletrofisiológicos. Conclusões: A presença de esclerite posterior em paciente com DCMT não é descrita na literatura, não se encontrando também relatos de outras doenças oculares inflamatórias, nestes pacientes.

  15. Mariátegui e a ocidentalização da política Mariátegui and the occidentalization of politics

    Directory of Open Access Journals (Sweden)

    Ricardo Melgar Bao

    2007-05-01

    Full Text Available A contribuição de Mariátegui para pensar o socialismo na América Latina é resgatada por meio das críticas à marginalização cultural e política dos povos não-ocidentais, bem como do particular uso que deu ao marxismo, acentuando-lhe as características universais através da apropriação cultural dos diversos contextos. Palavras-chave: América Latina. Oriente. Ocidente. Marxismo. Socialismo. Civilização. Cultura. Identidade. The contribution of Mariátequi for the view of socialism in Latin America is recovered not only through the criticism of the cultural and political marginal position of the non-western people but also through the particular way he used marxism, reinforcing its universal characteristics by the cultural appropriation of different cultural contexts. Keywords: Latin America. East. West. Marxism. Socialism. Civilization. Culture. Identity.

  16. The monster within: Mary Shelley's Frankenstein and a patient's fears of childbirth and mothering.

    Science.gov (United States)

    Almond, B R

    1998-08-01

    This paper explores the fantasy, widespread among women, of giving birth to a monster, particularly a psychological monster. The author hypothesises two central intrapsychic issues underlying these fears: monsters are viewed as 'incest babies' or as reflections of maternal aggression--evil, destructive parts of the mother passed on to the infant. Shame about femaleness is postulated as a third factor in the fear of producing something monstrous. Mary Shelley's novel, 'Frankenstein', is an iconic literary representation of these themes. The author presents and discusses some psychobiographical material about Mary Shelley, speculating on her motives for writing this novel and tracing the intrapsychic concerns about incest and aggression as reflected in the novel itself. Some recent feminist and psychoanalytic critical readings of 'Frankenstein' are referenced as they reflect on the novel's concern with themes of female sexuality and procreation. Clinical material from the author's own practice is presented to illustrate these fears, so similar to those with which Mary Shelley was dealing. A discussion, citing some relevant literature, follows.

  17. Brace modification improves aerobic performance in Charcot-Marie-Tooth disease: a single-subject design.

    Science.gov (United States)

    Bean, J; Walsh, A; Frontera, W

    2001-08-01

    Ankle-foot orthoses (AFOs) can lower energy expenditure in patients with hemiplegia by 10%-13%. Review of the lower motor injury literature reveals insufficient physiologic evidence supporting the use or modification of AFOs in patients with lower motor neuron injury and, specifically, progressive conditions such as Charcot-Marie-Tooth disease. We sought to test the hypothesis that optimal AFOs would improve submaximal aerobic performance and submaximal perceived exertion, while producing no change in maximal aerobic capacity. In an individual with Charcot-Marie-Tooth disease, a single-subject design study was used. An A-B-A design was used, with "A" corresponding to use of the patient's old AFOs and "B" corresponding to the newly prescribed AFOs. The subject underwent treadmill exercise tolerance testing using a modified Balke protocol. Indirect calorimetry was used to measure oxygen consumption per unit time (VO2), and the Borg scale was used to measure perceived exertion. At the same submaximal exercise intensities, VO2, rate-pressure product, and perceived exertion were all reduced when using the modified AFOs. Additionally, these conditions allowed the subject to conduct the treadmill exercise test 20% longer. Maximal VO2 remained constant under all conditions. Optimizing the AFO prescription in a patient with Charcot-Marie-Tooth disease can enhance physiologic performance and perceived exertion at submaximal activity levels. Larger controlled trials are necessary to further demonstrate such benefits in patients with progressive neuropathy and other causes of lower motor neuron injury.

  18. Analysis of Factors and Development Potential of Economic Clusters by Economic Activities in Mari El Republic

    Directory of Open Access Journals (Sweden)

    Viktor Aleksandrovich Golovin

    2017-12-01

    Full Text Available This article analyzes the factors that drive the development of economic clusters in Mari El Republic (Russia. This analysis allowed to reveal the potential of those clusters further development. I consider a shift-share method as one of the major methods to identify the factors that determine the expansion of economic clusters. The author proposes the modification of shift-share method using relative performance indicators to evaluate the intensity and qualitaty of clustering processes in the region. The article presents the results of empirical research of the economy of Mari El Republic by shift-share method (2005–2015 years in the context of economic activities according to the Federal State Statistics Service. After the analysis of three basic indicators, the leading and lagging economic activities were revealed for the period of 10 years. I paid special attention to the analysis of clustering potential of the Mari El Republic in the context of economic activities based on the Clustering Potential Index. This analysis shows promising economic activities and industries that may form cluster. The author discusses the compliance and possible conflicts of two methods used in the study. Further research of this field can focus on the of system analysis and identifying specific companies and production chains that form the basis of clustering

  19. Mary Shelley's Frankenstein: exploring neuroscience, nature, and nurture in the novel and the films.

    Science.gov (United States)

    Ginn, Sheryl R

    2013-01-01

    The story of Victor Frankenstein's quest to conquer death produced a legacy that has endured for almost 200 years. Powerful in its condemnation of the scientist's quest to achieve knowledge at any cost, Mary Shelley's Frankenstein is one of the most enduring novels of all time. It has never been out of print and has been translated to both stage and screen many times since its "birth." Numerous novels, short stories, and scripts have drawn upon Shelley's primary theme: the creation of a living organism from the dead, dying, and decaying body parts of human beings. Although Mary does not provide details of the animation process, particularly in her first edition, the process has been explored with a great deal of imagination and originality in the various cinematic portrayals of the story. Equally important as the theme of the scientist's quest for knowledge is the role that a creator plays in the life of its creation. Mary Shelley's novel pondered on how rejection would affect the offspring of such "unnatural" origins. In keeping with the "scientific" basis of the Creature's birth, cinematic portrayals attempted to provide a scientific rationale for the Creature's descent into madness and its evil behavior. From Robert Florey's initial script for the 1931 film directed by James Whale to the more recent films and television series, an abnormal brain is considered to be the cause of the madness and malignity of the Creature. © 2013 Elsevier B.V. All rights reserved.

  20. XAS studies of the effectiveness of iron chelating treatments of Mary Rose timbers

    Energy Technology Data Exchange (ETDEWEB)

    Berko, A; Schofield, E J; Chadwick, A V [School of Physical Sciences, University of Kent, CT2 7NR (United Kingdom); Smith, A D [STFC Daresbury Laboratory, Warrington, Cheshire, WA4 4AD (United Kingdom); Jones, A M [The Mary Rose Trust, HM Naval Base, Portsmouth, PO1 3LX (United Kingdom); Mosselmans, J F W, E-mail: a.berko@kent.ac.u [Diamond Light Source, Didcot, OX11 0DE (United Kingdom)

    2009-11-15

    The oxidation of sulfur in marine archaeological timbers under museum storage conditions is a recently identified problem, particularly for major artefacts such as historic ships excavated from the seabed. Recent work on the Vasa has stressed the role of iron in catalysing the oxidative degradation of the wood cellulose and the polyethylene glycols used to restore mechanical integrity to the timbers. In developing new treatment protocols for the long term preservation of Henry VIII of England's flagship, the Mary Rose, we are investigating the potential of chelating agents to neutralise and remove the iron products from the ships timbers. We have explored the use of aqueous solutions of chelating agents of calcium phytate, ethylenediaminetetraacetic acid (EDTA), diethylenetriaminepentaacetic acid (DTPA) and ammonium citrate to extract the iron compounds. All of these solutions exhibit some level of iron removal; however the key is to find the most effective concentration at pH of around 7 of the reagent solution, to minimise the treatment time and find the most cost-effective treatment for the whole of the Mary Rose hull. Fe K-edge XAFS data from samples of Mary Rose timbers, before and after treatment by the chelating agents mentioned has been collected. The data collected provide valuable insights into the effectiveness of the treatment solutions.

  1. Marie Sklodowska-Curie: teacher, mentor, research center founder, and '' la Patronne ''

    International Nuclear Information System (INIS)

    Hoffman, D.C.

    2011-01-01

    This year (2011) marks the 100 th Anniversary of the award of the Nobel Prize in Chemistry to Marie Sklodowska-Curie for her discoveries of radium and polonium and her studies of their properties. The United Nations has proclaimed 2011 as the '' International Year of Chemistry '', partly in recognition of this 100 th anniversary. A resolution of the Sejm of the Republic of Poland has also established 2011 as the Year of Maria Sklodowska-Curie. Marie Curie has been celebrated this year by a host of prestigious societies and in many countries all around the world for winning Nobel Prizes in both Physics (1903), for the discovery of radioactivity together with husband Pierre Curie and Henri Becquerel, and Chemistry (1911). She was the first woman to win Nobel Prizes in both Physics and Chemistry and the only one to date to win prizes in both physics and chemistry. Also remarkable was that after Pierre Curie's tragic and untimely death in 1906, she was put in charge of his lectures and laboratory, thus marking the first time in France that a woman occupied such a prestigious academic position, and opening the way for other women to follow. The current article will focus on some of the other notable accomplishments of Marie Curie that are not as commonly recognized, including her organizational and persuasive abilities, and her unique contributions as a teacher, mentor, research center founder, and laboratory '' la Patronne ''. (author)

  2. Climate change winners: receding ice fields facilitate colony expansion and altered dynamics in an Adélie penguin metapopulation.

    Science.gov (United States)

    LaRue, Michelle A; Ainley, David G; Swanson, Matt; Dugger, Katie M; Lyver, Phil O'B; Barton, Kerry; Ballard, Grant

    2013-01-01

    There will be winners and losers as climate change alters the habitats of polar organisms. For an Adélie penguin (Pygoscelis adeliae) colony on Beaufort Island (Beaufort), part of a cluster of colonies in the southern Ross Sea, we report a recent population increase in response to increased nesting habitat as glaciers have receded. Emigration rates of birds banded as chicks on Beaufort to colonies on nearby Ross Island decreased after 2005 as available habitat on Beaufort increased, leading to altered dynamics of the metapopulation. Using aerial photography beginning in 1958 and modern satellite imagery, we measured change in area of available nesting habitat and population size of the Beaufort colony. Population size varied with available habitat, and both increased rapidly since the 1990s. In accord with glacial retreat, summer temperatures at nearby McMurdo Station increased by ~0.50 °C per decade since the mid-1980s. Although the Ross Sea is likely to be the last ocean with an intact ecosystem, the recent retreat of ice fields at Beaufort that resulted in increased breeding habitat exemplifies a process that has been underway in the Ross Sea during the entire Holocene. Furthermore, our results are in line with predictions that major ice shelves and glaciers will retreat rapidly elsewhere in the Antarctic, potentially leading to increased breeding habitat for Adélie penguins. Results further indicated that satellite imagery may be used to estimate large changes in Adélie penguin populations, facilitating our understanding of metapopulation dynamics and environmental factors that influence regional populations.

  3. Climate change winners: receding ice fields facilitate colony expansion and altered dynamics in an Adélie penguin metapopulation.

    Directory of Open Access Journals (Sweden)

    Michelle A LaRue

    Full Text Available There will be winners and losers as climate change alters the habitats of polar organisms. For an Adélie penguin (Pygoscelis adeliae colony on Beaufort Island (Beaufort, part of a cluster of colonies in the southern Ross Sea, we report a recent population increase in response to increased nesting habitat as glaciers have receded. Emigration rates of birds banded as chicks on Beaufort to colonies on nearby Ross Island decreased after 2005 as available habitat on Beaufort increased, leading to altered dynamics of the metapopulation. Using aerial photography beginning in 1958 and modern satellite imagery, we measured change in area of available nesting habitat and population size of the Beaufort colony. Population size varied with available habitat, and both increased rapidly since the 1990s. In accord with glacial retreat, summer temperatures at nearby McMurdo Station increased by ~0.50 °C per decade since the mid-1980s. Although the Ross Sea is likely to be the last ocean with an intact ecosystem, the recent retreat of ice fields at Beaufort that resulted in increased breeding habitat exemplifies a process that has been underway in the Ross Sea during the entire Holocene. Furthermore, our results are in line with predictions that major ice shelves and glaciers will retreat rapidly elsewhere in the Antarctic, potentially leading to increased breeding habitat for Adélie penguins. Results further indicated that satellite imagery may be used to estimate large changes in Adélie penguin populations, facilitating our understanding of metapopulation dynamics and environmental factors that influence regional populations.

  4. Mutations in the MORC2 gene cause axonal Charcot-Marie-Tooth disease.

    Science.gov (United States)

    Sevilla, Teresa; Lupo, Vincenzo; Martínez-Rubio, Dolores; Sancho, Paula; Sivera, Rafael; Chumillas, María J; García-Romero, Mar; Pascual-Pascual, Samuel I; Muelas, Nuria; Dopazo, Joaquín; Vílchez, Juan J; Palau, Francesc; Espinós, Carmen

    2016-01-01

    Charcot-Marie-Tooth disease (CMT) is a complex disorder with wide genetic heterogeneity. Here we present a new axonal Charcot-Marie-Tooth disease form, associated with the gene microrchidia family CW-type zinc finger 2 (MORC2). Whole-exome sequencing in a family with autosomal dominant segregation identified the novel MORC2 p.R190W change in four patients. Further mutational screening in our axonal Charcot-Marie-Tooth disease clinical series detected two additional sporadic cases, one patient who also carried the same MORC2 p.R190W mutation and another patient that harboured a MORC2 p.S25L mutation. Genetic and in silico studies strongly supported the pathogenicity of these sequence variants. The phenotype was variable and included patients with congenital or infantile onset, as well as others whose symptoms started in the second decade. The patients with early onset developed a spinal muscular atrophy-like picture, whereas in the later onset cases, the initial symptoms were cramps, distal weakness and sensory impairment. Weakness and atrophy progressed in a random and asymmetric fashion and involved limb girdle muscles, leading to a severe incapacity in adulthood. Sensory loss was always prominent and proportional to disease severity. Electrophysiological studies were consistent with an asymmetric axonal motor and sensory neuropathy, while fasciculations and myokymia were recorded rather frequently by needle electromyography. Sural nerve biopsy revealed pronounced multifocal depletion of myelinated fibres with some regenerative clusters and occasional small onion bulbs. Morc2 is expressed in both axons and Schwann cells of mouse peripheral nerve. Different roles in biological processes have been described for MORC2. As the silencing of Charcot-Marie-Tooth disease genes have been associated with DNA damage response, it is tempting to speculate that a deregulation of this pathway may be linked to the axonal degeneration observed in MORC2 neuropathy, thus adding a

  5. Deep sleep after social stress: NREM sleep slow-wave activity is enhanced in both winners and losers of a conflict.

    Science.gov (United States)

    Kamphuis, Jeanine; Lancel, Marike; Koolhaas, Jaap M; Meerlo, Peter

    2015-07-01

    Sleep is considered to be a recovery process of prior wakefulness. Not only duration of the waking period affects sleep architecture and sleep EEG, the quality of wakefulness is also highly important. Studies in rats have shown that social defeat stress, in which experimental animals are attacked and defeated by a dominant conspecific, is followed by an acute increase in NREM sleep EEG slow wave activity (SWA). However, it is not known whether this effect is specific for the stress of social defeat or a result of the conflict per se. In the present experiment, we examined how sleep is affected in both the winners and losers of a social conflict. Sleep-wake patterns and sleep EEG were recorded in male wild-type Groningen rats that were subjected to 1h of social conflict in the middle of the light phase. All animals were confronted with a conspecific of similar aggression level and the conflict took place in a neutral arena where both individuals had an equal chance to either win or lose the conflict. NREM sleep SWA was significantly increased after the social conflict compared to baseline values and a gentle stimulation control condition. REM sleep was significantly suppressed in the first hours after the conflict. Winners and losers did not differ significantly in NREM sleep time, NREM sleep SWA and REM sleep time immediately after the conflict. Losers tended to have slightly more NREM sleep later in the recovery period. This study shows that in rats a social conflict with an unpredictable outcome has quantitatively and qualitatively largely similar acute effects on subsequent sleep in winners and losers. Copyright © 2015 Elsevier Inc. All rights reserved.

  6. Strahhovka bez granits / Viktoria Ladõnskaja

    Index Scriptorium Estoniae

    Ladõnskaja, Viktoria, 1981-

    2004-01-01

    Eesti liitumisel Euroopa Liiduga hakkavad liikluskindlustuse poliisid kehtima ka teiste riikide territooriumil võttes endale nn. rohelise kaardi funktsioonid, see põhjustab tariifide ligi kümneprotsendilise tõusu

  7. Winners and losers in flexible labor markets: the fate of women with chronic illness in contrasting policy environments--Sweden and Britain

    DEFF Research Database (Denmark)

    Burström, Bo; Holland, Paula; Diderichsen, Finn

    2003-01-01

    This study compares employment rates among men and women with and without chronic illness in the contrasting policy environments of Britain and Sweden, through analysis of household surveys for 1979-1995. Professional and managerial groups were winners in both countries, including during recession...... unskilled manual workers in Britain. British women with a chronic illness in the 1990s had less than half the employment rates of healthy women. Such social inequalities were much smaller and less consistent in Sweden, where the impact of illness was softened for all social groups. In Britain, workless men...

  8. Project winners - Ademe

    International Nuclear Information System (INIS)

    2015-01-01

    The French agency of environment and energy management (Ademe) is the operator in charge of innovation for accelerating the ecological and environmental transition. A credit of 3.3 billion euros is allocated to this goal in the framework of forward-looking investment. This budget aims at financing innovative projects of any size with the objective of developing tomorrow's industries. The projects cover the following topics: 1 - carbon-free energies and green chemistry: renewable energy sources (marine, solar, wind and geothermal energies), green chemistry and energy challenges (bio-resources, buildings, energy storage, hydrogen, CO 2 capture, storage and valorization, industry and agriculture), 2 - smart grids, 3 - circular economy (wastes and industrial ecology, sites and soils cleansing, water and biodiversity), 4 - future vehicles: road vehicle (mobility and logistics, electric-powered vehicles and charging facilities, hybrid and thermal engines, vehicles lightering, heavy-duty vehicles), rail and maritime transport. This document presents the financing system, a report of the previous investment campaign (2014), and the list of retained projects for the 2015 investment program

  9. Agribusiness Career Exploration Winner

    Science.gov (United States)

    Gutshall, Bill

    1976-01-01

    Describes the planning, development, status, and instructional materials used in a career awaremess program in agribusiness in Chillicothe, Missouri. The four classes in the program and the results of an appraisal are also described. (HD)

  10. Winner Take All

    DEFF Research Database (Denmark)

    Giacomin, Valeria

    focusing on collaboration across distant locations, to the dynamics of competition. The analysis concludes that: (i) clusters interact and advance through the exchange of knowledge on a shared institutional platform; (ii) competition emerges when players from one location increase their influence over...... the institutional platform to gain control over knowledge generation and transmission; and (iii) the comparative evaluation of business environments and their political risk complement location specificity in assessing cluster competitiveness.......Historically, agricultural crops have been transferred from their native locations to climatically similar ones. In the case of palm oil, the new location (Southeast Asia) outcompeted the native one (West Africa), thanks to a superior cluster organizational structure inherited from rubber...

  11. Be a Winner!

    Science.gov (United States)

    Rudolph, Marty

    1991-01-01

    Describes a step-by-step process for writing a winning application for the U.S. Department of Education Elementary (or Secondary) School Recognition Program. Underscores the importance of faculty involvement. Explains the application process, covering brainstorming, administrative questions, the first and final drafts, and use of various readers.…

  12. A rat model of Charcot-Marie-Tooth disease 1A recapitulates disease variability and supplies biomarkers of axonal loss in patients.

    Science.gov (United States)

    Fledrich, Robert; Schlotter-Weigel, Beate; Schnizer, Tuuli J; Wichert, Sven P; Stassart, Ruth M; Meyer zu Hörste, Gerd; Klink, Axel; Weiss, Bernhard G; Haag, Uwe; Walter, Maggie C; Rautenstrauss, Bernd; Paulus, Walter; Rossner, Moritz J; Sereda, Michael W

    2012-01-01

    Charcot-Marie-Tooth disease is the most common inherited neuropathy and a duplication of the peripheral myelin protein 22 gene causes the most frequent subform Charcot-Marie-Tooth 1A. Patients develop a slowly progressive dysmyelinating and demyelinating peripheral neuropathy and distally pronounced muscle atrophy. The amount of axonal loss determines disease severity. Although patients share an identical monogenetic defect, the disease progression is strikingly variable and the impending disease course can not be predicted in individual patients. Despite promising experimental data, recent therapy trials have failed. Established clinical outcome measures are thought to be too insensitive to detect amelioration within trials. Surrogate biomarkers of disease severity in Charcot-Marie-Tooth 1A are thus urgently needed. Peripheral myelin protein 22 transgenic rats harbouring additional copies of the peripheral myelin protein 22 gene ('Charcot-Marie-Tooth rats'), which were kept on an outbred background mimic disease hallmarks and phenocopy the variable disease severity of patients with Charcot-Marie-Tooth 1A. Hence, we used the Charcot-Marie-Tooth rat to dissect prospective and surrogate markers of disease severity derived from sciatic nerve and skin tissue messenger RNA extracts. Gene set enrichment analysis of sciatic nerve transcriptomes revealed that dysregulation of lipid metabolism associated genes such as peroxisome proliferator-activated receptor gamma constitutes a modifier of present and future disease severity. Importantly, we directly validated disease severity markers from the Charcot-Marie-Tooth rats in 46 patients with Charcot-Marie-Tooth 1A. Our data suggest that the combination of age and cutaneous messenger RNA levels of glutathione S-transferase theta 2 and cathepsin A composes a strong indicator of disease severity in patients with Charcot-Marie-Tooth 1A, as quantified by the Charcot-Marie-Tooth Neuropathy Score. This translational approach

  13. Marys Lake 69/115-kV transmission line upgrade and substation expansion projects

    International Nuclear Information System (INIS)

    1996-05-01

    Western Area Power Administration (Western) and the Platte River Power Authority (Platte River) propose to upgrade portions of the existing electric transmission and substation system that serves the Town of Estes Park, Colorado. The existing transmission lines between the Estes Power Plant Switchyard and the Marys Lake Substation include a 115,000 volt (115-kV) line and 69,000 volt (69-kV) line. Approximately one mile is a double-circuit 115/69-kV line on steel lattice structures, and approximately two miles consists of separate single-circuit 115-kV and a 69-kV lines, constructed on wood H-Frame structures. Both lines were constructed in 1951 by the US Bureau of Reclamation. The existing transmission lines are on rights-of-way (ROW) that vary from 75 feet to 120 feet and are owned by Western. There are 48 landowners adjacent to the existing ROW. All of the houses were built adjacent to the existing ROW after the transmission lines were constructed. Upgrading the existing 69-kV transmission line between the Marys Lake Substation and the Estes Power Plant Switchyard to 115-kV and expanding the Marys Lake Substation was identified as the most effective way in which to improve electric service to Estes Park. The primary purpose and need of the proposed project is to improve the reliability of electric service to the Town of Estes Park. Lack of reliability has been a historical concern, and reliability will always be less than desired until physical improvements are made to the electrical facilities serving Estes Park

  14. Marys Lake 69/115-kV transmission line upgrade and substation expansion projects

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-05-01

    Western Area Power Administration (Western) and the Platte River Power Authority (Platte River) propose to upgrade portions of the existing electric transmission and substation system that serves the Town of Estes Park, Colorado. The existing transmission lines between the Estes Power Plant Switchyard and the Marys Lake Substation include a 115,000 volt (115-kV) line and 69,000 volt (69-kV) line. Approximately one mile is a double-circuit 115/69-kV line on steel lattice structures, and approximately two miles consists of separate single-circuit 115-kV and a 69-kV lines, constructed on wood H-Frame structures. Both lines were constructed in 1951 by the US Bureau of Reclamation. The existing transmission lines are on rights-of-way (ROW) that vary from 75 feet to 120 feet and are owned by Western. There are 48 landowners adjacent to the existing ROW. All of the houses were built adjacent to the existing ROW after the transmission lines were constructed. Upgrading the existing 69-kV transmission line between the Marys Lake Substation and the Estes Power Plant Switchyard to 115-kV and expanding the Marys Lake Substation was identified as the most effective way in which to improve electric service to Estes Park. The primary purpose and need of the proposed project is to improve the reliability of electric service to the Town of Estes Park. Lack of reliability has been a historical concern, and reliability will always be less than desired until physical improvements are made to the electrical facilities serving Estes Park.

  15. The Gdap1 knockout mouse mechanistically links redox control to Charcot-Marie-Tooth disease.

    Science.gov (United States)

    Niemann, Axel; Huber, Nina; Wagner, Konstanze M; Somandin, Christian; Horn, Michael; Lebrun-Julien, Frédéric; Angst, Brigitte; Pereira, Jorge A; Halfter, Hartmut; Welzl, Hans; Feltri, M Laura; Wrabetz, Lawrence; Young, Peter; Wessig, Carsten; Toyka, Klaus V; Suter, Ueli

    2014-03-01

    The ganglioside-induced differentiation-associated protein 1 (GDAP1) is a mitochondrial fission factor and mutations in GDAP1 cause Charcot-Marie-Tooth disease. We found that Gdap1 knockout mice (Gdap1(-/-)), mimicking genetic alterations of patients suffering from severe forms of Charcot-Marie-Tooth disease, develop an age-related, hypomyelinating peripheral neuropathy. Ablation of Gdap1 expression in Schwann cells recapitulates this phenotype. Additionally, intra-axonal mitochondria of peripheral neurons are larger in Gdap1(-/-) mice and mitochondrial transport is impaired in cultured sensory neurons of Gdap1(-/-) mice compared with controls. These changes in mitochondrial morphology and dynamics also influence mitochondrial biogenesis. We demonstrate that mitochondrial DNA biogenesis and content is increased in the peripheral nervous system but not in the central nervous system of Gdap1(-/-) mice compared with control littermates. In search for a molecular mechanism we turned to the paralogue of GDAP1, GDAP1L1, which is mainly expressed in the unaffected central nervous system. GDAP1L1 responds to elevated levels of oxidized glutathione by translocating from the cytosol to mitochondria, where it inserts into the mitochondrial outer membrane. This translocation is necessary to substitute for loss of GDAP1 expression. Accordingly, more GDAP1L1 was associated with mitochondria in the spinal cord of aged Gdap1(-/-) mice compared with controls. Our findings demonstrate that Charcot-Marie-Tooth disease caused by mutations in GDAP1 leads to mild, persistent oxidative stress in the peripheral nervous system, which can be compensated by GDAP1L1 in the unaffected central nervous system. We conclude that members of the GDAP1 family are responsive and protective against stress associated with increased levels of oxidized glutathione.

  16. The Unintended Consequences of Technological Change: Winners and Losers from GM Technologies and the Policy Response in the Organic Food Market

    Directory of Open Access Journals (Sweden)

    Stuart Smyth

    2015-06-01

    Full Text Available It is often said that innovations create winners and losers. All innovations are somewhat disruptive, but some have more distributed effects. We have a sense of who the winners are and how much they gain. Yet, how much do losers actually lose? Organic farmers frequently like to publicly announce that they are the losers following the commercialization of genetically modified (GM crops, yet consumers in search of non-GM products have helped increase demand for organic products, something that would not have occurred in the absence of GM crops. Are organic farmers really losers? This article lays out the argument that were it not for the commercialization of GM crop varieties in the mid-1990s, organic production and food sectors would not be at the level they enjoy today. That is, the commercialization of GM crops has made the organic industry better off than had GM crops not been commercialized. Theoretical modelling of the organic benefits is complemented by supportive market data. The article concludes that in spite of numerous vocal offerings about the adverse impacts suffered by the organic industry due to GM crop production, the organic industry has gained significantly from that which they vociferously criticize.

  17. Differences in certain features of the basketball game of players in the final game, against the criteria: The winner/loser

    Directory of Open Access Journals (Sweden)

    Rubin Pavle

    2013-01-01

    Full Text Available This paper focuses on the characteristics of the game (applied technical and tactical activity for attack realisation, shooting performance, position of players in team, the segment of the field where the ball is received and where the shot is made from in the final matches of top three club competitions. The aim of this study was to determine whether there are differences in observed characteristics of the basketball game between teams separated by the winner/loser criteria. The sample consisted of all matches of the final games of three league competitions (American professional (NBA league, the Euro-league and the Serbian Super-league played in the season 2011/12. By applying multivariate statistical procedures in the monitored segment application of technical and tactical activities of players, it was observed that the winning team, unlike the defeated team, significantly featured a technical - tactical element of shooting, while in the defeated teams (as opposed to the winners elements of action were dominant: dribbling, penetration, shot and dribbling, jump stop, fake, shot. Higher percentage of using only shooting (without the requirement for other elements of attack used to create an opportunity for the eventual shot realization can point primarily to the successful organization of the attacks (in this case - the winning team. As for the position of players in the team, with the teams that won in the monitored matches, statistically significant was the dominance of the forwards in relation to the defeated teams, which featured more centers in the offense attempts.

  18. Marie Darrieussecq, Rapporto di polizia. Le accuse di plagio e altri metodi di controllo della scrittura

    Directory of Open Access Journals (Sweden)

    Niccolò Scaffai

    2012-04-01

    Full Text Available Something strange happened to Marie Darrieussecq. It wasn’t that she was born in France, in Bayonne, in 1969. Or that she is a writer (in addition to being a scholar of literature and psychoanalyst who has published works of fiction, autobiographical short stories and literary essays. There is nothing strange about that. What is strange is that half of her novels have been considered, by various readers and by other writers, «imitations», «copies», «psychic plagiarism», and even «manuscript theft».

  19. Mariátegui, el escritor vanguardista contemporáneo

    Directory of Open Access Journals (Sweden)

    Álvaro Campuzano Arteta

    2005-10-01

    Full Text Available Este ensayo rememora el encuentro ocurrido a inicios del siglo XX entre la literatura vanguardista y el socialismo. Recorriendo un camino que va de los comentarios de José Carlos Mariátegui sobre el cine de Charlie Chaplin, a la exploración de la narrativa vanguardista de Martín Adán, la reflexión aquí propuesta se funda en el pensamiento de Walter Benjamin. Para la elaboración de este trabajo se han desarrollado algunas de las secciones de una tesis de maestría escrita para el Dartmouth College.

  20. Geothermal heating project at St. Mary's Hospital, Pierre, South Dakota. Final report

    Energy Technology Data Exchange (ETDEWEB)

    1984-12-01

    St. Mary's Hospital, Pierre, South Dakota, with the assistance of the US Department of Energy, drilled a 2176 ft well into the Madison Aquifer ot secure 108/sup 0/F artesian flow water at 385 gpm (475 psig shut-in pressure). The objective was to provide heat for domestic hot water and to space heat 163,768 sq. ft. Cost savings for the first three years were significant and, with the exception of a shutdown to replace some corroded pipe, the system has operated reliably and continuously for the last four years.

  1. The recommissioning of the treatment plant at Mary Kathleen Uranium Ltd

    International Nuclear Information System (INIS)

    Thomas, J.

    1978-01-01

    The recommissioning of the plant at Mary Kathleen involved several distinct phases. The previous plant process was modified significantly, the plant capacity was increased by the addition of new equipment and the existing equipment was in most cases overhauled. This equipment was either reused in its original duty or relocated. Maintenance requirements after the plant was commissioned were high because of the amount of modified equipment and also because some old items of equipment were deliberately not overhauled during recommissioning. The equipment that was overhauled has operated reliably. However some new equipment has not been as satisfactory

  2. Psychometrics evaluation of Charcot-Marie-Tooth Neuropathy Score (CMTNSv2) second version, using Rasch analysis.

    Science.gov (United States)

    Sadjadi, Reza; Reilly, Mary M; Shy, Michael E; Pareyson, Davide; Laura, Matilde; Murphy, Sinead; Feely, Shawna M E; Grider, Tiffany; Bacon, Chelsea; Piscosquito, Giuseppe; Calabrese, Daniela; Burns, Ted M

    2014-09-01

    Charcot-Marie-Tooth Neuropathy Score second version (CMTNSv2) is a validated clinical outcome measure developed for use in clinical trials to monitor disease impairment and progression in affected CMT patients. Currently, all items of CMTNSv2 have identical contribution to the total score. We used Rasch analysis to further explore psychometric properties of CMTNSv2, and in particular, category response functioning, and their weight on the overall disease progression. Weighted category responses represent a more accurate estimate of actual values measuring disease severity and therefore could potentially be used in improving the current version. © 2014 Peripheral Nerve Society.

  3. The cult of St Mary Magdalene de' Pazii in Baroque-era Krakow

    Directory of Open Access Journals (Sweden)

    Jan Małecki

    1998-12-01

    Full Text Available In the second half of the 17th century Krakow entered a period of decline. Following the great epidemic of 1651-1652 and the havoc wrought by a tragic war with Sweden, the city struggled to rise from the ruins. One may find it hard to believe that the churches were promptly rebuilt, and the construction of new temples, which were frequently magnificent and artistically impressive, was quick. The period was marked with the worship of Catherina de' Pazzi (whose religious name is Mary Magdalene, a Florence Carmelite nun.

  4. Mary Ellen Avery’s Research Career- Remembrance of Things Past

    Directory of Open Access Journals (Sweden)

    John Steven Torday

    2014-04-01

    Full Text Available Mary Ellen Avery’s research is recognized as a milestone in biomedical research. She had discovered the underlying cause of Hyaline Membrane Disease, surfactant deficiency, fostering ever more vigorous efforts to reduce neonatal mortality in the burgeoning practice of Neonatology. Neonatology is the only clinical discipline that began as an experiment, making it a model for biomedical research. Avery knew that the concerted effort to treat preterm newborns could potentially do more harm than good, violating her oath to Hippocrates, if not held to the highest scientific standards. She remained true to that pledge throughout her career, as recounted in this Review.

  5. Low-sampling-rate M-ary multiple access UWB communications in multipath channels

    KAUST Repository

    Alkhodary, Mohammad T.

    2015-08-31

    The desirable characteristics of ultra-wideband (UWB) technology are challenged by formidable sampling frequency, performance degradation in the presence of multi-user interference, and complexity of the receiver due to the channel estimation process. In this paper, a low-rate-sampling technique is used to implement M-ary multiple access UWB communications, in both the detection and channel estimation stages. A novel approach is used for multiple-access-interference (MAI) cancelation for the purpose of channel estimation. Results show reasonable performance of the proposed receiver for different number of users operating many times below Nyquist rate.

  6. La maladie de charcot-marie-tooth de type i (CMT1) | Adoukonou ...

    African Journals Online (AJOL)

    La maladie de Charcot-Marie-Tooth de type 1 (CMT1) est la neuropathie héréditaire la plus fréquente ; il en existe plusieurs formes ou sous-types. La littérature foisonne de données récentes grâce surtout aux avancées des analyses de biologie moléculaire et aux études corrélatives des données cliniques, ...

  7. Malignant melanoma and Charcot-Marie-Tooth disease: A further case

    Energy Technology Data Exchange (ETDEWEB)

    Manoukian, S.; Briscioli, V.; Lalatta, F. [Instituti Clinici di Perfezionamento, Milan (Italy)

    1997-01-20

    In a previous issue of this journal, Greene et al. described 2 patients with Charcot-Marie-Tooth (CMT) disease who later developed cutaneous malignant melanoma. Although the development of the two diseases in the same patient may have occurred by chance, the authors raised the possibility of a shared neural crest defect or a genetic linkage. Among the patients reported by Greene et al., one had a dominant form of CMT. The patient`s mother and brother were similarly affected. A paternal aunt died of melanoma. The second patient had a neuronal type of CMT. His brother showed the same disease, but the parents were not examined. 7 refs.

  8. Intermediate Charcot-Marie-Tooth disease: an electrophysiological reappraisal and systematic review.

    Science.gov (United States)

    Berciano, José; García, Antonio; Gallardo, Elena; Peeters, Kristien; Pelayo-Negro, Ana L; Álvarez-Paradelo, Silvia; Gazulla, José; Martínez-Tames, Miriam; Infante, Jon; Jordanova, Albena

    2017-08-01

    Charcot-Marie-Tooth disease (CMT) is the most frequent form of inherited neuropathy with great variety of phenotypes, inheritance patterns, and causative genes. According to median motor nerve conduction velocity (MNCV), CMT is divided into demyelinating (CMT1) with MNCV below 38 m/s, axonal (CMT2) with MNCV above 38 m/s, and intermediate CMT with MNCV between 25 and 45 m/s. In each category, transmission may be autosomal dominant, autosomal recessive, or X-linked. The nosology of intermediate CMT is controversial because of concerns about electrophysiological delimitation. A systematic computer-based literature search was conducted on PubMed, using the following MeSH: (1) intermediate Charcot-Marie-Tooth; (2) X-linked intermediate Charcot-Marie-Tooth; and (3) X-linked Charcot-Marie-Tooth and electrophysiology. We retrieved 225 articles reporting X-linked CMT or intermediate CMT with electrophysiological information. After eligibility, 156 papers were used for this review. In assessing median MNCV, compound muscle action potential (CMAP) amplitudes were taken into account. In cases with attenuated CMAP and wherever possible, proximal median MNCV was used for accurate definition of conduction slowing in the intermediate range. In the vast majority of males with X-linked CMT associated with GJB1 mutation (CMTX1), median MNCV was intermediate. CMT associated with DRP2 mutation is another well-documented X-linked intermediate disorder. Autosomal dominant intermediate CMT (DI-CMT) encompasses 11 different types; six of them with assigned phenotype MIM number and the remaining five being unnumbered. Based on available electrophysiological information, we wonder if DI-CMTA should be reclassified within CMT2. Autosomal recessive intermediate CMT (RI-CMT) covers four numbered MIM phenotypes though, in accordance with reported electrophysiology, two of them (RI-CMTB and RI-CMTD) should probably be reclassified within AR-CMT2. We conclude that intermediate CMT is a complex

  9. Atypical presentation of Charcot-Marie-Tooth disease 1A: A case report.

    Science.gov (United States)

    Kulkarni, Shilpa D; Sayed, Rafat; Garg, Meenal; Patil, Varsha A

    2015-11-01

    Charcot-Marie-Tooth (CMT) 1A is the most common form of CMT disease and is characterized by duplication of Peripheral myelin protein 22 (PMP22) gene. We report a boy with genetically confirmed CMT1A disease having clinical involvement of hypoglossal and glossopharyngeal nerves, as well as asymmetrical and primarily upper limb involvement. These atypical features widen the clinical spectrum of CMT1A, leading to interesting observations about PMP22 gene related disorders and varied clinical expression of similar genetic mutations. Copyright © 2015 Elsevier B.V. All rights reserved.

  10. Marie Sktodowska Curie a metallurgist: her study of magnetic properties of quenched steels (1894-1897); Marie Sklodowska Curie metallurgiste: etude des proprietes magnetiques des aciers trempes (1894-1897)

    Energy Technology Data Exchange (ETDEWEB)

    Hardouin Duparc, Olivier

    2012-02-15

    Marie Sktodowska Curie's first scientific work, and her first two papers, dealt with the study of the magnetic properties of quenched steels as a function of their chemistry and their quenching treatment. It lasted three years and was instrumental in her meeting Pierre Curie, then a specialist in solid state magnetism. Knowledge of iron and steels, although already complicated was still far from perfect. Marie learned to use many samples of different chemistry provided by several manufacturers. This sense of systematic study proved essential when she started to investigate the possible emission of uranic rays by various materials. (author)

  11. La tesis de Mariátegui sobre el carácter feudal de la economía colonial peruana Mariátegui's thesis on the feudal character of Peruvian colonial economy

    Directory of Open Access Journals (Sweden)

    David Sobrevilla

    2010-06-01

    Full Text Available José Carlos Mariátegui, en su "Esquema de la evolución económica" [del Perú], el primero de los 7 ensayos (1928, consideró que la economía colonial peruana era feudal. En nuestro libro El marxismo de Mariátegui y su aplicación a los '7 ensayos (2005', manifestamos que con la información disponible hoy, tal afirmación se había tornado insostenible. Por su parte, Antonio Melis señaló que la caracterización de Mariátegui podía ser discutida. En este artículo se examinan las observaciones planteadas por Melis. Se considera en primer lugar la posición de A. G. Frank, así como las reacciones que suscitó. Se exponen a continuación las razones en contra de la tesis de Mariátegui sobre el carácter feudal de la economía peruana colonial. Se examina luego la tesis de Ruggiero Romano sobre el feudalismo en general y sobre el iberoamericano en particular. Se realiza, por último, una consideración final.José Carlos Mariátegui, in his "Outline of economic evolution" [Peru], the first of the 7 ensayos (1928, considered Peru's colonial economy was feudal. In our book Mariátegui's Marxism and its application to '7 ensayos' (2005, we said that the information available today, such a claim had become untenable. For his part, Antonio Melis said Mariátegui's characterization could be discussed. This article discusses the observation raised by Melis. It considers the position of A. G. Frank, as well as the reactions to it. Then the reasons against Mariátegui's thesis are also considered. The thesis on feudalism in general and the Latin American one in particular is examined by Ruggiero Romano. A final one consideration is done as a conclusion.

  12. Clio goes roller-skating: Images of Memory in some poems by Mary Kennan Herbert Clio goes roller-skating: Images de la mémoire dans quelques poèmes de Mary Kennan Herbert

    Directory of Open Access Journals (Sweden)

    Jennifer Kilgore

    2009-11-01

    Full Text Available A few words about Mary Kennan HerbertMary Kennan Herbert is a writer with midwestern roots. She was born in 1938 in St. Louis, Missouri, and spent most of her childhood there. During her adolescent years she lived in Tennessee. She obtained a University degree in art from Peabody College in Nashville. In New York, she pursued a career as editor in a publishing house until the 1980s, when a merger ended her job security. After several attempts at working for different publishers, she started s...

  13. Tectonomorphic evolution of Marie Byrd Land - Implications for Cenozoic rifting activity and onset of West Antarctic glaciation

    Science.gov (United States)

    Spiegel, Cornelia; Lindow, Julia; Kamp, Peter J. J.; Meisel, Ove; Mukasa, Samuel; Lisker, Frank; Kuhn, Gerhard; Gohl, Karsten

    2016-10-01

    The West Antarctic Rift System is one of the largest continental rifts on Earth. Because it is obscured by the West Antarctic Ice Sheet, its evolution is still poorly understood. Here we present the first low-temperature thermochronology data from eastern Marie Byrd Land, an area that stretches 1000 km along the rift system, in order to shed light on its development. Furthermore, we petrographically analysed glacially transported detritus deposited in the marine realm, offshore Marie Byrd Land, to augment the data available from the limited terrestrial exposures. Our data provide information about the subglacial geology, and the tectonic and morphologic history of the rift system. Dominant lithologies of coastal Marie Byrd Land are igneous rocks that intruded (presumably early Paleozoic) low-grade meta-sedimentary rocks. No evidence was found for un-metamorphosed sedimentary rocks exposed beneath the ice. According to the thermochronology data, rifting occurred in two episodes. The earlier occurred between 100 and 60 Ma and led to widespread tectonic denudation and block faulting over large areas of Marie Byrd Land. The later episode started during the Early Oligocene and was confined to western Pine Island Bay area. This Oligocene tectonic activity may be linked kinematically to previously described rift structures reaching into Bellingshausen Sea and beneath Pine Island Glacier, all assumed to be of Cenozoic age. However, our data provide the first direct evidence for Cenozoic tectonic activity along the rift system outside the Ross Sea area. Furthermore, we tentatively suggest that uplift of the Marie Byrd Land dome only started at 20 Ma; that is, nearly 10 Ma later than previously assumed. The Marie Byrd Land dome is the only extensive part of continental West Antarctica elevated above sea level. Since the formation of a continental ice sheet requires a significant area of emergent land, our data, although only based on few samples, imply that extensive

  14. Voice and Body: Emotional Proximity and Physical Distance in Marie de France’s ‘Laustic’

    OpenAIRE

    Zisa, Jessica

    2015-01-01

    Through the lens of feminist theoretical questions and gender studies, this paper explores the relationship between voice and body and the emotional and physical distance that occurs between genders in Marie de France’s Laustic. As a medieval woman writer, Marie provides a textual space to examine the emotional closeness and psychological distance that occurs within the patriarchal structure that delineates gender relations within the convention of marriage. This lai or poetic narrative artic...

  15. La puissance du regard chez Marie-Claire Blais: de la honte à l’affirmation de soi

    Directory of Open Access Journals (Sweden)

    Eva Pich Ponce

    2009-04-01

    Full Text Available In Marie-Claire Blais’ first novels, the images of eyes and glances acquire a great significance. They highlight the character’srelationships, conformism or rebelliousness. The other’s constant gaze arouses feelings of shame and remorse in the character whichis being observed. This article will illustrate how Marie-Claire Blais’ portrayals of eyes and glances allow her to draw attention tothe character’s relationships and to denounce the dramatic consequences the notions of guilt and shame have in the searchof individual identity.

  16. Marie Underist, P. Mustapääst ja 1920. aastate ballaadidest. On Marie Under, P. Mustapää, and Ballads of the 1920s

    Directory of Open Access Journals (Sweden)

    Satu Grünthal

    2012-04-01

    Full Text Available The purpose of this article is to discuss the poetic relations between two neighbouring countries with a particular emphasis on the ballad. For both Estonian and Finnish poetry, the 1920s were a productive and interesting period for the writing of ballads. I will focus my inquiry on two poets, Marie Under and P. Mustapää. Closer analysis will be carried out of one motif, the self-sacrificing woman, which is found in the ballads of both poets, particularly in view of the importance of these ballad themes in the context of the art and social life of the 1920s. From the perspective of comparing Finnish and Estonian literature, it is interesting to examine common features and reciprocal influences in their ballads. For Finnish poet Martti Haavio, whose pen name was P. Mustapää, Estonian poetry of the 1920s was an important source of inspiration and models, a fact that he emphasized especially in his memoirs, and which was also expressed mainly in his later poetry. Marie Under held an important place among the Estonian poets who inspired P. Mustapää; in the article this is demonstrated through a thorough analysis of P. Mustapää’s poem „Under the Laurel Trees” („Varjossa laakerien”. The poem moves on two levels. On the one hand, its content is the poet`s childhood memory, on the other – as is so often characteristic of P. Mustapää, the poem treats metapoetically of the process of how poetry and art are born, and of the wonder of creation. Both Marie Under and P. Mustapää wrote many ballads, and in addition, P. Mustapää used ballad motifs in many of his other poems. In the article, the motif of the self-sacrificing woman is discussed with respect to the works of both poets. Closer examination is given to P. Mustapää’s poem „The White Lady of Haapsalu”, a poem that contains ballad material, and to Under’s ballad „The Birth of Naissaar”, with additional comments on her ballads „False Foot”(„Ebajalg” and

  17. THE DEAD-LIVING-MOTHER: MARIE BONAPARTE'S INTERPRETATION OF EDGAR ALLAN POE'S SHORT STORIES.

    Science.gov (United States)

    Obaid, Francisco Pizarro

    2016-06-01

    Princess Marie Bonaparte is an important figure in the history of psychoanalysis, remembered for her crucial role in arranging Freud's escape to safety in London from Nazi Vienna, in 1938. This paper connects us to Bonaparte's work on Poe's short stories. Founded on concepts of Freudian theory and an exhaustive review of the biographical facts, Marie Bonaparte concluded that the works of Edgar Allan Poe drew their most powerful inspirational force from the psychological consequences of the early death of the poet's mother. In Bonaparte's approach, which was powerfully influenced by her recognition of the impact of the death of her own mother when she was born-an understanding she gained in her analysis with Freud-the thesis of the dead-living-mother achieved the status of a paradigmatic key to analyze and understand Poe's literary legacy. This paper explores the background and support of this hypothesis and reviews Bonaparte's interpretation of Poe's most notable short stories, in which extraordinary female figures feature in the narrative.

  18. Monological Drama to Reshape the Northern Irish Identity: A Night in November by Marie Jones

    Directory of Open Access Journals (Sweden)

    Virginie Privas

    2010-03-01

    Full Text Available In this contemporary one-man theatre play, Marie Jones’s character, Kenneth McCallister, is prompted to break free from the prejudices in and against Northern Ireland. Indeed, the playwright aims at finding new ways to deconstruct the preconceived idea that there are two different identities in Northern Ireland closely linked to the division between two religious communities. Instead, she seeks connections, even with the Irish who migrated (the diasporic dimension, though, is not to be discussed within this paper. The author explores this possibility through the psychological evolution of a Northern Irish Protestant who comes to lack references in terms of identity. On stage, he recalls the events that launched him on a quest to redefine his identity, an identity in which his religious denomination is taken into account but is not the only community marker. Marie Jones eventually offers an insight into what being and feeling Irish means for someone who has always lived as a Protestant in Northern Ireland. Monologue and the notion of “frontiers” (be they social, political, geographical, historical or theatrical that emerge only to be destroyed, are some of the theatrical devices she resorts to in order to voice her aim in  this experimental play which ultimately proposes to reshape the contours of Northern Irish drama about the Troubles.

  19. Book presentation followed by discussion: "HEP - still an unfeminine profession?" with Mary K Gaillard

    CERN Multimedia

    CERN. Geneva; Gaillard, Mary K

    2016-01-01

    In 1981 Mary K Gaillard became the first woman on the physics faculty at the University of California at Berkeley. Her career as a theoretical physicist spanned the period from the inception — in the late 1960s and early 1970s — of what is now known as the Standard Model of particle physics and its experimental confirmation, culminating with the discovery of the Higgs particle in 2012. Her book A Singularly Unfeminine Profession recounts Gaillard's experiences as a woman in a very male-dominated field, while tracing the development of the Standard Model as she witnessed it and participated in it. Following the book presentation, Prof. Valerie Gibson from the University of Cambridge will comment on her own journey and how it is to be a woman in the world of physics today during a discussion round with P.E.Mary K Gaillard and the audience. The discussion round will be moderated by Geneviève Guinot, the CERN Diversity Programme Leader. Coffee will be served at 3:30pm. Th...

  20. Marie Curie, les femmes et la science, d'hier à aujourd'hui

    CERN Multimedia

    CERN. Geneva; Mariotti, Chiara; Vicinanza, Domenico

    2017-01-01

    Marie Curie, les femmes et la science, d'hier à aujourd'hui Conférence par Hélène Langevin-Joliot Avec la participation de l'Echo du Reculet de Thoiry. L'enregistrement et la liste d'attente sont déjà complets... Mais il n'est pas rare que des personnes réservent et ne viennent pas. Nous réassignerons les places libérées selon la règle "premier arrivé, premier inscrit". Au vu de la forte demande, la conférence sera également disponible en vidéoconférence : lien d'accès "webcast" disponible en bas de cette page. Hélène Langevin-Joliot, directrice de recherche émérite en physique nucléaire fondamentale au CNRS à Orsay, est aussi la fille de Frédéric et Irène Joliot-Curie (prix Nobel de chimie en 1935) et la petite-fille de Pierre Curie (prix Nobel de physique en 1903) et de Marie Curie (prix Nobel de physique en 1903 et prix Nobel de chimie en 1911). Hélène Langevin-Joliot nous parlera de sa vie scientifique, de l’histoire extraordinai...