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Sample records for wingate army depot

  1. Master Environmental Plan: Fort Wingate Depot Activity, Gallup, New Mexico

    Energy Technology Data Exchange (ETDEWEB)

    Biang, C.A.; Yuen, C.R.; Biang, R.P.; Antonopoulos, A.A.; Ditmars, J.D.

    1990-12-01

    The master environmental plan is based on an environmental assessment of the areas requiring environmental evaluation (AREEs) at Fort Wingate Depot Activity near Gallup, New Mexico. The Fort Wingate Depot Activity is slated for closure under the Base Closure and Realignment Act, Public Law 100--526. The MEP assesses the current status, describes additional data requirements, recommends actions for the sites, and establishes a priority order for actions. The plan was developed so that actions comply with hazardous waste and water quality regulations of the State of New Mexico and applicable federal regulations. It contains a brief history of the site, relevant geological and hydrological information, and a description of the current status for each AREE along with a discussion of the available site-specific data that pertain to existing or potential contamination and the impact on the environment. 35 refs., 27 figs., 23 tabs.

  2. Evaluation of Sierra Army Depot Groundwater Contamination

    National Research Council Canada - National Science Library

    Granetto, Paul

    1997-01-01

    ...), September 28, 1996. The Congressional conferees were concerned about allegations from a group of investors that the Army precipitously and abruptly changed its position on permits and applications to develop water...

  3. Analysis of Tobyhanna Army Depot's Radio Frequency Identification (RFID) Pilot Program: RFID as an Asset Management Tool

    National Research Council Canada - National Science Library

    Miertschin, Keith W; Forrest, Brian D

    2005-01-01

    ...) used for inventory and asset management at the Tobyhanna Army Maintenance Depot. Tobyhanna Army Depot recently partnered with WhereNet Corporation for a pilot program to incorporate a real-time locating system that uses RFID...

  4. Geochemical evidence of groundwater flow paths and the fate and transport of constituents of concern in the alluvial aquifer at Fort Wingate Depot Activity, New Mexico, 2009

    Science.gov (United States)

    Robertson, Andrew J.; Henry, David W.; Langman, Jeffery B.

    2013-01-01

    As part of an environmental investigation at Fort Wingate Depot Activity, New Mexico, the U.S. Geological Survey, in cooperation with the U.S. Army Corps of Engineers, interpreted aqueous geochemical concentrations to better understand the groundwater flow paths and the fate and transport of constituents of concern in the alluvial aquifer underlying the study area. The fine-grained nature of the alluvial matrix creates a highly heterogeneous environment, which adds to the difficulty of characterizing the flow of groundwater and the fate of aqueous constituents of concern. The analysis of the groundwater geochemical data collected in October 2009 provides evidence that is used to identify four groundwater flow paths and their extent in the aquifer and indicates the dominant attenuation processes for the constituents of concern. The extent and interaction of groundwater flow paths were delineated by the major ion concentrations and their relations to each other. Four areas of groundwater recharge to the study area were identified based on groundwater elevations, hydrogeologic characteristics, and geochemical and isotopic evidence. One source of recharge enters the study area from the saturated alluvial deposits underlying the South Fork of the Puerco River to the north of the study area. A second source of recharge is shown to originate from a leaky cistern containing production water from the San Andres-Glorieta aquifer. The other two sources of recharge are shown to enter the study area from the south: one from an arroyo valley draining an area to the south and one from hill-front recharge that passes under the reported release of perchlorate and explosive constituents. The spatial extent and interaction of groundwater originating from these various sources along identified flow paths affect the persistence and attenuation of constituents of concern. It was determined that groundwater originating in the area of a former explosives’ wash-out operation and an

  5. Trip Reports. Hazardous Waste Minimization and Control at Army Depots

    Science.gov (United States)

    1989-08-01

    regulations because it processes aircraft. Most depot personel expressed the belief that control technology is too expensive and may not be practicable because...perldot, gloss beads, and plastic. A few depots W use some sood as a blasting media, but It is being phased out as a remlt of helth conrns. A da base... technology . Letterkenny is interested in recycling chromium rinse water. These efforts are potential projects under the current Task Order. Tobyhanna’s

  6. Base Closure and Realignment Act (BRAC) Cleanup Plan, Sacramento Army Depot, Sacramento, California

    Science.gov (United States)

    1995-10-01

    deal.BeetStaffWirtier one point, Sacrampnto developer The Sacramento Army Depot is "I came and said This is thlMarvin " Buzz " Oafea talked to a a...class of persistent, board-spectrum insecticides, that linger in the environment and accumulate in the food chain. Among them are DDT, aldrin , dieldrin

  7. Planning Documents Known Releases SWMUs Tooele Army Depot Tooele, Utah. Volume 1: Corrective Measures Study Work Plan

    National Research Council Canada - National Science Library

    2000-01-01

    ...) at Tooele Army Depot (TEAD; formerly the North Area), Tooele, Utah. The CMS Work Plan addresses seven of the nine SWMUs that were identified in the Phase II Resource Conservation and Recovery Act (RCRA...

  8. Artificial intelligence technology assessment for the US Army Depot System Command

    Energy Technology Data Exchange (ETDEWEB)

    Pennock, K A

    1991-07-01

    This assessment of artificial intelligence (AI) has been prepared for the US Army's Depot System Command (DESCOM) by Pacific Northwest Laboratory. The report describes several of the more promising AI technologies, focusing primarily on knowledge-based systems because they have been more successful in commercial applications than any other AI technique. The report also identifies potential Depot applications in the areas of procedural support, scheduling and planning, automated inspection, training, diagnostics, and robotic systems. One of the principal objectives of the report is to help decisionmakers within DESCOM to evaluate AI as a possible tool for solving individual depot problems. The report identifies a number of factors that should be considered in such evaluations. 22 refs.

  9. Fifteen Years of Web Based Data Management at Tooele Army Depot

    Science.gov (United States)

    2012-03-28

    And, Tooele Army Depot Goes Online Following an EPA audit of nine federal  facilities, Tooele Army Depot ( TEAD )  proactively begins the process of...District contracted with  Synectics to provide an innovative solution  allowing  TEAD  stakeholders to access the same  data the prime contractor was...Ellin, do you know llle project Suzan Hughes document for Parson’s TEAD SVYMU-58 Certified All the Data in One Place Laboratories & Contractors Legend

  10. Tooele Army Depot - South Area Suspected Release Units. RCRA Facility Investigation - Phase 2, for SWMUs 1, 25, and 27

    National Research Council Canada - National Science Library

    Kamp, Susan; Tate, D. J; Zigich, Daniel; Moss, Pamela; Warner, Alan; Leslie, Mark; Bieniulis, Carol

    1995-01-01

    ... Waste Management Units (SWMUs) 1 and 25 and an RFI-Phase I program to determine the presence or absence of contamination at SWMU 37 at Tooele Army Depot South Area (TEAD-S), near Tooele, Utah. SWMUs 1 and 25...

  11. Disposal of chemical agents and munitions stored at Anniston Army Depot, Anniston, Alabama

    Energy Technology Data Exchange (ETDEWEB)

    Hunsaker, D.B. Jr.; Zimmerman, G.P.; Hillsman, E.L.; Miller, R.L.; Schoepfle, G.M.; Johnson, R.O.; Tolbert, V.R.; Kroodsma, R.L.; Rickert, L.W.; Rogers, G.O.; Staub, W.P.

    1990-09-01

    The purpose of this Phase I report is to examined the proposed implementation of on-site disposal at Anniston Army Depot (ANAD) in light of more detailed and more recent data than those included in the Final Programmatic Environmental Impact Statement (EPEIS). Two principal issues are addressed: (1) whether or not the new data would result in identification of on-site disposal at ANAD as the environmentally preferred alternative (using the same selection method and data analysis tools as in the FPEIS), and (2) whether or not the new data indicate the presence of significant environmental resources that could be affected by on-site disposal at ANAD. In addition, a status report is presented on the maturity of the disposal technology (and now it could affect on-site disposal at ANAD). Inclusion of these more recent data into the FPEIS decision method resulted in confirmation of on-site disposal for ANAD. No unique resources with the potential to prevent or delay implementation of on-site disposal at ANAD have been identified. A review of the technology status identified four principal technology developments that have occurred since publication of the FPEIS and should be of value in the implementation of on-site disposal at ANAD: the disposal of nonlethal agent at Pine Bluff Arsenal, located near Pine Bluff, Arkansas; construction and testing of facilities for disposal of stored lethal agent at Johnston Atoll, located about 1300 km (800 miles) southwest of Hawaii in the Pacific Ocean; lethal agent disposal tests at the chemical agent pilot plant operations at Tooele Army Depot, located near Salt Lake City, Utah; and equipment advances. 18 references, 13 figs., 10 tabs.

  12. Audit Report on the Sacramento Army Depot Internal Review and Audit Compliance Office's "Audits of Warranties, Quality Deficiency Reports, and Reports of Discrepancies"

    National Research Council Canada - National Science Library

    1992-01-01

    The Sacramento Army Depot (SAAD) Internal Review and Audit Compliance Office (Internal Review) issued an audit report, "Audit of Warranties, Quality Deficiency Reports, and Reports of Discrepancies," on July 20, 1990...

  13. Changes Are Needed to the Army Contract with Sikorsky to Use Existing DoD Inventory and Control Costs at the Corpus Christi Army Depot

    Science.gov (United States)

    2011-11-03

    contingency stock for requirements outside the CCAD/Sikorsky contract. 6 The DoD EMALL is a full-service eCommerce site, which strives to be the single...Acquisition System,” DoDI, 4151.21, “Public-Private Partnerships for Depot-Level Maintenance,” and DoD 4140.1-R require full costs and benefits be...LMP, which prevented the Army from achieving the expected benefits from LMP. Furthermore, GAO Report No. GAO-11-139, “Additional Oversight and

  14. BIA Wingate High School WWTF, Fort Wingate, NM: NN0020958

    Science.gov (United States)

    NPDES Permit and Fact Sheet explaining EPA's action under the Clean Water Act to issue NPDES Permit No. NN0020958 to Bureau of Indian Affairs (BIA) Wingate High School Wastewater Treatment Lagoon, Fort Wingate, NM.

  15. CHAWS user`s guide: System description and standard operating procedures, Lexington-Blue Grass Army Depot

    Energy Technology Data Exchange (ETDEWEB)

    Martins, S.A.; Shinn, J.H. [eds.

    1993-05-01

    The Chemical Hazard Warning System (CHAWS) is designed to collect meteorological data and to display, in real time, the dispersion of hazardous chemicals that may result from an accidental release. Meteorological sensors have been placed strategically around the Lexington-Blue Grass Army Depot and are used to calculate direction and hazard distance for the release. Based on these data, arrows depicting the release direction and distance traveled are graphically displayed on a computer screen showing a site map of the facility. The objectives of CHAWS are as follows: To determine the trajectory of the center of mass of released material from the measured wind field; to calculate the dispersion of the released material based on the measured lateral turbulence intensity (sigma theta); to determine the height of the mixing zone by measurement of the inversion height and wind profiles up to an altitude of about 1 km at sites that have SODAR units installed; to archive meteorological data for potential use in climatological descriptions for emergency planning; to archive air-quality data for preparation of compliance reports; and to provide access to the data for near real time hazard analysis purposes. CHAWS sites are located at the Pine Bluff Arsenal, Arkansas, Edgewood area of Aberdeen Proving Ground, Maryland, Tooele Depot, Utah, Lexington-Blue Grass Depot, Kentucky, and Johnston Island in the Pacific. The systems vary between sites with different features and various types of hardware. The basic system, however, is the same. Nonetheless, we have tailored the manuals to the equipment found at each site.

  16. A WINGATE TEST

    Directory of Open Access Journals (Sweden)

    TP Souza-Junior

    2014-10-01

    Full Text Available Reactive oxygen species are produced during anaerobic exercise mostly by Fe ions released into plasma and endothelial/muscle xanthine oxidase activation that generates uric acid (UA as the endpoint metabolite. Paradoxically, UA is considered a major antioxidant by virtue of being able to chelate pro-oxidative iron ions. This work aimed to evaluate the relationship between UA and plasma markers of oxidative stress following the exhaustive Wingate test. Plasma samples of 17 male undergraduate students were collected before, 5 and 60 min after maximal anaerobic effort for the measurement of total iron, haem iron, UA, ferric-reducing antioxidant activity in plasma (FRAP, and malondialdehyde (MDA, biomarker of lipoperoxidation. Iron and FRAP showed similar kinetics in plasma, demonstrating an adequate pro-/antioxidant balance immediately after exercise and during the recovery period (5–60 min. Slight variations of haem iron concentrations did not support a relevant contribution of rhabdomyolysis or haemolysis for iron overload following exercise. UA concentration did not vary immediately after exercise but rather increased 29% during the recovery period. Unaltered MDA levels were concomitantly measured. We propose that delayed UA accumulation in plasma is an auxiliary antioxidant response to post-exercise (iron-mediated oxidative stress, and the high correlation between total UA and FRAP in plasma (R-Square = 0.636; p = 0.00582 supports this hypothesis.

  17. Pengelolaan Jaringan Internet Dengan Proxy Wingate

    OpenAIRE

    Winarti, Titin

    2004-01-01

    Proxy adalah bagian dari protokol yang berfungsi sebagai link untuk host tunggal atau sebagai link untuk beberapa host antarajaringan dan jaringan lain. Proxy wingate adalah software yang digunakan untuk berbagi koneksi internet melalui satu alamat IPyang terintegrasi ke internet.

  18. PENGELOLAAN JARINGAN INTERNET DENGAN PROXY WINGATE

    OpenAIRE

    Titin Winarti

    2005-01-01

    Proxy adalah bagian dari protokol yang berfungsi sebagai link untuk host tunggal atau sebagai link untuk beberapa host antarajaringan dan jaringan lain. Proxy wingate adalah software yang digunakan untuk berbagi koneksi internet melalui satu alamat IPyang terintegrasi ke internet.

  19. PENGELOLAAN JARINGAN INTERNET DENGAN PROXY WINGATE

    Directory of Open Access Journals (Sweden)

    Titin Winarti

    2005-01-01

    Full Text Available Proxy adalah bagian dari protokol yang berfungsi sebagai link untuk host tunggal atau sebagai link untuk beberapa host antarajaringan dan jaringan lain. Proxy wingate adalah software yang digunakan untuk berbagi koneksi internet melalui satu alamat IPyang terintegrasi ke internet.

  20. Army Business Transformation: The Utility of Using Corporate Business Models within the Institutional Army

    National Research Council Canada - National Science Library

    Bailer, Jr., John J

    2007-01-01

    .... Through a survey of the literature of published corporate business plans and models, military reports, Army depot case studies, and comparative analysis of emerging computer software technology...

  1. Enhanced Preliminary Assessment Report: Fort Wingate Depot Activity Gallup, New Mexico

    Science.gov (United States)

    1990-03-01

    drying beds suspected of holding contaminated sediments and soils. No liquid effluent is presently discharged to the surface drainage system from the...continuously when mine effluent was pumped into it. Effluent from the city of Gallup wastewater treatment system and discharge from bedrock units also...stenciling, removing Solvents, carbon tetrachloride, rusty bomb fins, refusing TNT shells 501 Boiler plant Tannin , sodium phosphate dusts I 503 Bomb

  2. Risperidone (depot) for schizophrenia.

    Science.gov (United States)

    Sampson, Stephanie; Hosalli, Prakash; Furtado, Vivek A; Davis, John M

    2016-04-14

    Risperidone is the first new generation antipsychotic drug made available in a long-acting injection formulation. To examine the effects of depot risperidone for treatment of schizophrenia or related psychoses in comparison with placebo, no treatment or other antipsychotic medication.To critically appraise and summarise current evidence on the resource use, cost and cost-effectiveness of risperidone (depot) for schizophrenia. We searched the Cochrane Schizophrenia Group's Register (December 2002, 2012, and October 28, 2015). We also checked the references of all included studies, and contacted industry and authors of included studies. Randomised clinical trials comparing depot risperidone with other treatments for people with schizophrenia and/or schizophrenia-like psychoses. Two review authors independently selected trials, assessed trial quality and extracted data. For dichotomous data, we calculated the risk ratio (RR), with 95% confidence interval (CI). For continuous data, we calculated mean differences (MD). We assessed risk of bias for included studies and created 'Summary of findings' tables using GRADE. Twelve studies, with a total of 5723 participants were randomised to the following comparison treatments: Risperidone depot versus placebo Outcomes of relapse and improvement in mental state were neither measured or reported. In terms of other primary outcomes, more people receiving placebo left the study early by 12 weeks (1 RCT, n=400, RR 0.74 95% CI 0.63 to 0.88, very low quality evidence), experienced severe adverse events in short term (1 RCT, n=400, RR 0.59 95% CI 0.38 to 0.93, very low quality evidence). There was however, no difference in levels of weight gain between groups (1 RCT, n=400, RR 2.11 95% CI 0.48 to 9.18, very low quality evidence). Risperidone depot versus general oral antipsychotics The outcome of improvement in mental state was not presented due to high levels of attrition, nor were levels of severe adverse events explicitly reported

  3. Allometric Scaling of Wingate Anaerobic Power Test Scores in Women

    Science.gov (United States)

    Hetzler, Ronald K.; Stickley, Christopher D.; Kimura, Iris F.

    2011-01-01

    In this study, we developed allometric exponents for scaling Wingate anaerobic test (WAnT) power data that are reflective in controlling for body mass (BM) and lean body mass (LBM) and established a normative WAnT data set for college-age women. One hundred women completed a standard WAnT. Allometric exponents and percentile ranks for peak (PP)…

  4. Ursula Wingate. The Effectiveness of Different Learner Dictionaries ...

    African Journals Online (AJOL)

    rbr

    Investigation into the Use of Dictionaries for Reading Comprehension by Inter- mediate Learners of German. 2002, X + 301 pp. ... empirical research conducted in dictionary use. Ursula Wingate is responsible for the ... Her expertise in applied linguistics and in learning strategies has been a particular asset in this research.

  5. Wingate, Ursula (2015). Academic Literacy and Student Diversity

    African Journals Online (AJOL)

    Wingate, Ursula (2015). Academic Literacy and Student Diversity: The Case of Inclusive Practice. Bristol: Multilingual Matters. Reviewed by Thengani H. Ngwenya*. Book review. * Prof. Thengani H. Ngwenya is Director of the Centre for Excellence in Learning and Teaching of the. Durban University of Technology, Durban, ...

  6. Depot Maintenance: Executed Workload and Maintenance Operations at DOD Depots

    Science.gov (United States)

    2017-02-03

    software. This enclosure provides detailed information about each of the 17 depots on executed workload, personnel, capital investments, process...services’ depots from fiscal year 2012 through 2015, and provides detailed information for each of the 17 depots, on executed workload, personnel...Depot Maintenance: Additional Information Needed to Meet DOD’s Core Capability Reporting Requirements, GAO-13-194 (Washington, D.C.: Feb. 11, 2013

  7. Army Logistician. Volume 40, Issue 1, January-February 2008

    Science.gov (United States)

    2008-02-01

    published in Army Logistician or similar venues both inside and outside the Depart- ment of Defense. Enlightened members and stew - ards of the...Army does business at its depots. Gold Prize recipients were— • The Joint Manufacturing and Technology Cen- ter at Rock Island, Illinois, for...avoidance of almost $4 million. • Tobyhanna Army Depot, Pennsylvania, for work on the AN/TPQ-36 Firefinder radar antenna. Silver Prize recipients were

  8. Evolving the Army’s Government-Owned Contractor-Operated (GOCO) Facilities Business Model

    Science.gov (United States)

    2011-03-11

    two are GOGOs, Tooele Army Depot ( TEAD ) and Anniston Army Depot (ANAD), and the other two are GOCO‟s, Hawthorne Army Ammunition (HWAAD) and Holston...Making-the-Military-More-Efficient. (accessed January 27, 2011) 15 Kathy Anderson, “ TEAD Participates in Special Installation Pilot Study”, May 26...2010 http://www.army.mil/-news/2010/05/26/39847- tead -participates-in-special-installation-pilot-study/ (accessed February, 27 2011) 16 Ibid. 21

  9. Makahiki+WattDepot

    DEFF Research Database (Denmark)

    Johnson, Philip M.; Xu, Yongwen; Brewer, Robert S.

    2013-01-01

    Satisfying the radically different requirements and operating assumptions of the next generation smart grid requires new kinds of software that enable research and experimentation into the ways that electrical energy production and consumption can be collected, analyzed, visualized, and provided ......, Django, Memcache). In this paper, we detail the novel features of WattDepot and Makahiki, our experiences using them for research and education, and additional ways they can be used for next generation energy research and education....

  10. Wingate Test is a Strong Predictor of 1500m Performance in Elite Speed Skaters

    NARCIS (Netherlands)

    Hofman, Nico; Orie, Jac; Hoozemans, Marco J M; Foster Jr., Carl; de Koning, Jos J

    2017-01-01

    Wingate test scores are strongly associated with anaerobic capacity in athletes involved in speed-endurance sports. In speed skating Wingate results are known to predict performance cross-sectionally, but have not been investigated relative to their ability to predict performance longitudinally.

  11. Function Point Analysis Depot

    Science.gov (United States)

    Muniz, R.; Martinez, El; Szafran, J.; Dalton, A.

    2011-01-01

    The Function Point Analysis (FPA) Depot is a web application originally designed by one of the NE-C3 branch's engineers, Jamie Szafran, and created specifically for the Software Development team of the Launch Control Systems (LCS) project. The application consists of evaluating the work of each developer to be able to get a real estimate of the hours that is going to be assigned to a specific task of development. The Architect Team had made design change requests for the depot to change the schema of the application's information; that information, changed in the database, needed to be changed in the graphical user interface (GUI) (written in Ruby on Rails (RoR and the web service/server side in Java to match the database changes. These changes were made by two interns from NE-C, Ricardo Muniz from NE-C3, who made all the schema changes for the GUI in RoR and Edwin Martinez, from NE-C2, who made all the changes in the Java side.

  12. Isometric knee extensor fatigue following a Wingate test: peripheral and central mechanisms.

    Science.gov (United States)

    Fernandez-del-Olmo, M; Rodriguez, F A; Marquez, G; Iglesias, X; Marina, M; Benitez, A; Vallejo, L; Acero, R M

    2013-02-01

    Central and peripheral fatigue have been explored during and after running or cycling exercises. However, the fatigue mechanisms associated with a short maximal cycling exercise (30 s Wingate test) have not been investigated. In this study, 10 volunteer subjects performed several isometric voluntary contractions using the leg muscle extensors before and after two bouts of cycling at 25% of maximal power output and two bouts of Wingate tests. Transcranial magnetic stimulation (TMS) and electrical motor nerve stimulation (NM) were applied at rest and during the voluntary contractions. Maximal voluntary contraction (MVC), voluntary activation (VA), twitch amplitude evoked by electrical nerve stimulation, M wave and motor potential evoked by TMS (MEP) were recorded. MVC, VA and twitch amplitude evoked at rest by NM decreased significantly after the first and second Wingate tests, indicating central and peripheral fatigue. MVC and VA, but not the twitch amplitude evoked by NM, recovered before the second Wingate test. These results suggest that the Wingate test results in a decrease in MVC associated with peripheral and central fatigue. While the peripheral fatigue is associated with an intramuscular impairment, the central fatigue seems to be the main reason for the Wingate test-induced impairment of MVC. © 2011 John Wiley & Sons A/S.

  13. Wingate Test as a Strong Predictor of 1500-m Performance in Elite Speed Skaters.

    Science.gov (United States)

    Hofman, Nico; Orie, Jac; Hoozemans, Marco J M; Foster, Carl; de Koning, Jos J

    2017-11-01

    Wingate test scores are strongly associated with anaerobic capacity in athletes involved in speed-endurance sports. In speed skating Wingate results are known to predict performance cross-sectionally but have not been investigated relative to their ability to predict performance longitudinally. To investigate whether Wingate tests performed during summer training are predictive of 1500-m speed-skating performance the subsequent winter in elite speed skaters. Wingate test results from the summer training periods and 1500-m performances during the subsequent winter were analyzed over a 3-y period in 5 female and 8 male elite (Olympic, World Championship, and World Cup medalists) speed skaters. Regression analyses using generalized estimating equations (GEE) were used to estimate the relationship between Wingate test variables and 1500-m speed-skating performance. Wingate peak power (PP) and mean power (MP) were used to predict 1500-m time and 400-m lap times. Improvements of 1 W/kg on PP and MP in women predict improvements of -0.75 s and -2.05 s, respectively, on 1500-m time (World Record 110.85 s). In men, improvements in PP and MP were associated with performance improvements of -0.92 s and -2.32 s on 1500-m time per 1 W/kg (World Record 101.04 s). Wingate test results achieved during the summer training period are a good predictor of improvements in 1500-m speed-skating performance during the subsequent winter. For the smallest worthwhile improvement in 1500-m performance, a gain in PP and MP of 2.1% and 1.4% (0.38 and 0.14 W/kg) for females and 1.2% and 0.9% (0.29 and 0.12 W/kg) for males is needed.

  14. Postactivation potentiation effect of overloaded cycling on subsequent cycling Wingate performance.

    Science.gov (United States)

    Doma, Kenji; Leicht, Anthony S; Schumann, Moritz; Nagata, Akinori; Senzaki, Kazuma; Woods, Carl E

    2018-01-04

    This study examined the postactivation potentiation effects of overloaded cycling on subsequent Wingate performance. Twenty anaerobic-trained men took part in this study. The participants were randomly allocated to complete three testing sessions separated by 7 days. Each week, participants either undertook a control session (CON) consisting of a sub-maximal cycling warm-up protocol followed by a Wingate test, or separate sessions involving an overloaded 10-second cycling PAP protocol followed by a Wingate test at 5 (T5) or 10 (T10) minutes, post-PAP protocol. Power outputs, cadence, total work, fatigue rate, heart rate and capillary lactate measures were recorded from each Wingate test. Measures were compared between these sessions and between sessions that generated the greatest peak power output (Bestpeak- P) and mean power output (Bestmean-P) via repeated measures ANOVA with effect sizes (ES) also calculated. A significantly greater mean power output, total work and lactate level were exhibited during the T10 condition compared to the CON condition (p cycling protocol increased power output and lactate measures in anaerobic-trained men during a 30-second, Wingate test. Overloaded cycling enhances subsequent anaerobic performance and is therefore likely to provide greater training stimuli for anaerobically trained individuals.

  15. The 1991 Department of the Army Service Response Force exercise: Procedural Guide SRFX-91

    Energy Technology Data Exchange (ETDEWEB)

    Madore, M.A.; Thomson, R.S.; Haffenden, R.A.; Baldwin, T.E.; Meleski, S.A.

    1991-09-01

    This procedural guide was written to assist the US Army in planning for a chemical emergency exercise at Tooele Army Depot in Utah. The roles of various members of the emergency response community are described for various accident scenarios, and the relationships between the various responders are identified. For the June 1991 exercise at Tooele, the emergency response community includes the command structure at Tooele Army Depot; the US Army Service Response Force and other Department of Defense agencies; emergency response personnel from Tooele, Salt Lake, and Utah counties and municipal governments; the Utah Comprehensive Emergency Management Agency and other state agencies; and various federal agencies.

  16. Neural adaptations after short-term wingate-based high-intensity interval training

    Science.gov (United States)

    Vera-Ibañez, Antonio; Colomer-Poveda, David; Romero-Arenas, Salvador; Viñuela-García, Manuel; Márquez, Gonzalo

    2017-01-01

    Objectives: This study examined the neural adaptations associated with a low-volume Wingate-based High Intensity Interval Training (HIIT). Methods: Fourteen recreationally trained males were divided into an experimental (HIIT) and a control group to determine whether a short-term (4 weeks) Wingate-based HIIT program could alter the Hoffmann (H-) reflex, volitional (V-) wave and maximum voluntary contraction (MVC) of the plantar-flexor muscles, and the peak power achieved during a Wingate test. Results: Absolute and relative peak power increased in the HIIT group (ABS_Ppeak: +14.7%, P=0.001; and REL_Ppeak: +15.0%, P=0.001), but not in the control group (ABS_Ppeak: P=0.466; and REL_Ppeak: P=0.493). However, no significant changes were found in the MVC (P>0.05 for both groups). There was a significant increase in H-reflex size after HIIT (+24.5%, P=0.004), while it remained unchanged in the control group (P=0.134). No significant changes were observed either in the V-wave or in the Vwave/Mwave ratio (P>0.05 for both groups). Conclusion: The Wingate-based training led to an increased peak power together with a higher spinal excitability. However, no changes were found either in the volitional wave or in the MVC, indicating a lack of adaptation in the central motor drive. PMID:29199186

  17. Space Transportation Infrastructure Supported By Propellant Depots

    Science.gov (United States)

    Smitherman, David; Woodcock, Gordon

    2011-01-01

    A space transportation infrastructure is described that utilizes propellant depots to support all foreseeable missions in the Earth-Moon vicinity and deep space out to Mars. The infrastructure utilizes current expendable launch vehicles such as the Delta IV Heavy, Atlas V, and Falcon 9, for all crew, cargo, and propellant launches to orbit. Propellant launches are made to a Low-Earth-Orbit (LEO) Depot and an Earth-Moon Lagrange Point 1 (L1) Depot to support new reusable in-space transportation vehicles. The LEO Depot supports missions to Geosynchronous Earth Orbit (GEO) for satellite servicing, and to L1 for L1 Depot missions. The L1 Depot supports Lunar, Earth-Sun L2 (ESL2), Asteroid, and Mars missions. A Mars Orbital Depot is also described to support ongoing Mars missions. New concepts for vehicle designs are presented that can be launched on current 5-meter diameter expendable launch vehicles. These new reusable vehicle concepts include a LEO Depot, L1 Depot, and Mars Orbital Depot based on International Space Station (ISS) heritage hardware. The high-energy depots at L1 and Mars orbit are compatible with, but do not require, electric propulsion tug use for propellant and/or cargo delivery. New reusable in-space crew transportation vehicles include a Crew Transfer Vehicle (CTV) for crew transportation between the LEO Depot and the L1 Depot, a new reusable Lunar Lander for crew transportation between the L1 Depot and the lunar surface, and a Deep Space Habitat (DSH) to support crew missions from the L1 Depot to ESL2, Asteroid, and Mars destinations. A 6 meter diameter Mars lander concept is presented that can be launched without a fairing based on the Delta IV heavy Payload Planners Guide, which indicates feasibility of a 6.5 meter fairing. This lander would evolve to re-usable operations when propellant production is established on Mars. Figure 1 provides a summary of the possible missions this infrastructure can support. Summary mission profiles are presented

  18. Storage depot for radioactive material

    International Nuclear Information System (INIS)

    Szulinski, M.J.

    1983-01-01

    Vertical drilling of cylindrical holes in the soil, and the lining of such holes, provides storage vaults called caissons. A guarded depot is provided with a plurality of such caissons covered by shielded closures preventing radiation from penetrating through any linear gap to the atmosphere. The heat generated by the radioactive material is dissipated through the vertical liner of the well into the adjacent soil and thus to the ground surface so that most of the heat from the radioactive material is dissipated into the atmosphere in a manner involving no significant amount of biologically harmful radiation. The passive cooling of the radioactive material without reliance upon pumps, personnel, or other factor which might fail, constitutes one of the most advantageous features of this system. Moreover this system is resistant to damage from tornadoes or earthquakes. Hermetically sealed containers of radioactive material may be positioned in the caissons. Loading vehicles can travel throughout the depot to permit great flexibility of loading and unloading radioactive materials. Radioactive material can be shifted to a more closely spaced caisson after ageing sufficiently to generate much less heat. The quantity of material stored in a caisson is restricted by the average capacity for heat dissipation of the soil adjacent such caisson

  19. Historic Properties Report: Sierra Army Depot, Herlong, California.

    Science.gov (United States)

    1984-07-01

    documented in accordance with Documentation Level I of these standards. In cases where standard measured drawings are unable to record sig - nificant features...NERLONG. CALIFORNIA 96113 PLY O November 8, 1983 Intelligence Office Melvvn Green & Associates, Inc. 690 North Sepulveda Boulevard Suite 120 El

  20. Implementation of Plastic Media Blasting (PMB) at US Army Depots

    Science.gov (United States)

    1988-01-01

    Corporation (Fort Worth, TX) NMER: New Mexico Engineering Research (Albuquerque, NM) AFWAL: Materials Laboratory Wright-Patterson Air Force Base (Dayton...aS*𔃿m~*.5r)f rI=im.I @ .A =ei -- ni 40M no I-1 C4 ~ In .I" i l -V -61 - 5inu,.. on o n*(f5 nini nmi not -P i’s% -IF* *P. -0s’ *7S* (5I r 1^o="ff r...lU~ EN M MT i4 PoeNM. I 184C TURCO PRODUCTS. INC. 9 7300 BOLSA AVENUE. WESTMINSTER. CALIFORNIA 92664-3000 * 7141890-300 TURCO BLAST MEDIA Plastic Media

  1. TIME-OF-DAY EFFECTS ON EMG PARAMETERS DURING THE WINGATE TEST IN BOYS

    Directory of Open Access Journals (Sweden)

    Hichem Souissi

    2012-09-01

    Full Text Available In boys, muscle power and strength fluctuate with time-of-day with morning nadirs and afternoon maximum values. However, the exact underlying mechanisms of this daily variation are not studied yet. Thus, the purpose of this study was to examine the time-of-day effects on electromyographic (EMG parameters changes during a Wingate test in boys. Twenty-two boys performed a 30-s Wingate test (measurement of muscle power and fatigue at 07:00 and 17:00-h on separate days. Surface EMG activity was recorded in the Vastus lateralis, rectus femoris and vastus medialis muscles throughout the test and analyzed over a 5-s span. The root-mean-square (RMS and mean-power-frequency (MPF were calculated. Neuromuscular efficiency (NME was estimated from the ratio of power to RMS. Muscle power (8.22 ± 0.92 vs. 8.75 ± 0.99 W·kg-1 for peak power and 6.96 ± 0. 72 vs. 7.31 ± 0.77 W·kg-1 for mean power, p < 0.001 and fatigue (30.27 ± 7.98 vs. 34.5 ± 10. 15 %, p < 0.05 during the Wingate test increased significantly from morning to evening. Likewise, MPF (102.14 ± 18.15 vs. 92.38 ± 12.39 Hz during the first 5-s, p < 0.001 and NME (4.78 ± 1.7 vs. 3.88 ± 0.79 W·mV-1 during the first 5-s, p < 0.001 were higher in the evening than the morning; but no significant time-of-day effect was noticed for RMS. Taken together, these results suggest that peripheral mechanisms are more likely the cause of the child's diurnal variations of muscle power and fatigue during the Wingate test

  2. DEPOT database: Reference manual and user's guide

    International Nuclear Information System (INIS)

    Clancey, P.; Logg, C.

    1991-03-01

    DEPOT has been developed to provide tracking for the Stanford Linear Collider (SLC) control system equipment. For each piece of equipment entered into the database, complete location, service, maintenance, modification, certification, and radiation exposure histories can be maintained. To facilitate data entry accuracy, efficiency, and consistency, barcoding technology has been used extensively. DEPOT has been an important tool in improving the reliability of the microsystems controlling SLC. This document describes the components of the DEPOT database, the elements in the database records, and the use of the supporting programs for entering data, searching the database, and producing reports from the information

  3. Locating Depots for Capacitated Vehicle Routing

    DEFF Research Database (Denmark)

    Gørtz, Inge Li; Nagarajan, Viswanath

    2011-01-01

    We study a location-routing problem in the context of capacitated vehicle routing. The input to k-LocVRP is a set of demand locations in a metric space and a fleet of k vehicles each of capacity Q. The objective is to locate k depots, one for each vehicle, and compute routes for the vehicles so t...

  4. Depot medroxyprogesterone injectable contraception at the ...

    African Journals Online (AJOL)

    the introduction of post-abortal and puerperal administrations of depot medroxyprogesterone acetate and its new formulation; depo sub-Q provera in all our .... disease, uterine fibroids, ectopic pregnancy, iron- deficiency anemia and ovarian .... contraception. Clinical Gynaecologic Endocrinology and. Infertility. 15th ed.

  5. Techno-economic analysis of decentralized biomass processing depots.

    Science.gov (United States)

    Lamers, Patrick; Roni, Mohammad S; Tumuluru, Jaya S; Jacobson, Jacob J; Cafferty, Kara G; Hansen, Jason K; Kenney, Kevin; Teymouri, Farzaneh; Bals, Bryan

    2015-10-01

    Decentralized biomass processing facilities, known as biomass depots, may be necessary to achieve feedstock cost, quantity, and quality required to grow the future U.S. bioeconomy. In this paper, we assess three distinct depot configurations for technical difference and economic performance. The depot designs were chosen to compare and contrast a suite of capabilities that a depot could perform ranging from conventional pelleting to sophisticated pretreatment technologies. Our economic analyses indicate that depot processing costs are likely to range from ∼US$30 to US$63 per dry metric tonne (Mg), depending upon the specific technology implemented and the energy consumption for processing equipment such as grinders and dryers. We conclude that the benefits of integrating depots into the overall biomass feedstock supply chain will outweigh depot processing costs and that incorporation of this technology should be aggressively pursued. Copyright © 2015. Published by Elsevier Ltd.

  6. Test-Retest Reliability of the 20-sec Wingate Test to Assess Anaerobic Power in Children with Cerebral Palsy

    NARCIS (Netherlands)

    Dallmeijer, Annet J.; Scholtes, Vanessa A. B.; Brehm, Merel-Anne; Becher, Jules G.

    2013-01-01

    Objective: The aim of this study was to determine the test-retest reliability of the 20-sec Wingate anaerobic test in children with cerebral palsy. Design: Participants were 22 ambulant children with cerebral palsy, with Gross Motor Function Classification System levels I (limitations in advanced

  7. Test-retest reliability of the 20-sec Wingate test to assess anaerobic power in children with cerebral palsy

    NARCIS (Netherlands)

    Dallmeijer, A.J.; Scholtes, V.A.B.; Brehm, M.A.; Becher, J.G.

    2013-01-01

    OBJECTIVE: The aim of this study was to determine the test-retest reliability of the 20-sec Wingate anaerobic test in children with cerebral palsy. DESIGN: Participants were 22 ambulant children with cerebral palsy, with Gross Motor Function Classification System levels I (limitations in advanced

  8. Army AL&T, January-March 2008

    Science.gov (United States)

    2008-03-01

    12/18/2007 12:25 PM Page 70 facility, Tooele Army Depot ( TEAD ) in Tooele, UT, as well as from DAC. These activities maintain a skilled staff of... TEAD have developed robotic vehicles for antipersonnel mine clearance, lifting towers for security surveillance and com- munications systems used by...plosive device threat grew, CAAA and TEAD were both called upon to pro- duce armored cabs for M939 series trucks. In FY02, DAC devel- oped AMMOHELP, an

  9. Building for Peace: U.S. Army Engineers in Europe 1945-1991

    Science.gov (United States)

    2005-01-01

    designated the 507th Engineer Shop Company) was attache~ to the. depot. This unit’s mission was to repair and maintain mec ~amcal equ1pment for the Army...Sverdrup Medal established in memory of distinguished military engineer Maj. Gen. Lei £ Sverdrup. The award recognized Rhoades’ extraordinary

  10. Oxygen uptake during Wingate tests for arms and legs in swimmers and water polo players

    Directory of Open Access Journals (Sweden)

    Colantonio Emilson

    2003-01-01

    Full Text Available OBJECTIVE: The aim of the present study is to compare the values of the maximal oxygen uptake (O2 max during two consecutive bouts in Wingate tests for arms and legs in swimmers (S and water polo players (WP. METHODS: Sample - seven national level athletes (4 S and 3 WP, age 17,90 ± 2,14 years, body mass 71,41 ± 6,84 kg, height 176,65 ± 7,02 cm, % body fat 13,23 ± 4,18. Two Wingate bouts with 30 sec each with 3 min interval between them, for arms and legs in alternated days. Oxygen uptake: breath-by-breath using the gas analysis system K4 b² Cosmed. Statistical analysis: Wilcoxon test for dependent variables and Kolmogorov-Smirnov test for independent variables. RESULTS: The mean values found at the O2 peak (PO2, mean power (MP and peak power (PP for each bout of the Wingate test, for arms and legs. For Arms: PO2 = 55.16 ± 5.72 ml.kg-1.min-1, MP = 5.28 ± 0.59 watts.kg-1 and PP = 6.71 ± 0.88 watts.kg-1 got in the first bout (1st Arms and PO2 = 60.12 ± 6.10 ml.kg-1.min-1, MP = 5.03 ± 0.40 watts.kg-1 and PP = 6.25 ± 0.51 watts.kg-1, got in the second bout (2nd Arms. For legs: PO2 = 55.66 ± 6.85 ml.kg-1.min-1, MP = 4.75 ± 1.79 watts.kg-1 and PP = 7.44 ± 1.96 watts.kg-1 got in the first bout (1st Legs and PO2 = 62.09 ± 5.99 ml.kg-1.min-1, MP = 4.28 ± 1.47 watts.kg-1 and PP = 6.68 ± 1.63 watts.kg-1 got in the second bout (2nd Legs. DISCUSSION AND CONCLUSION: All variables studied did not present significant difference among arms and legs, as much the first as the second bout for arms for PO2 (p < 0.05. There was no difference between the PM mean values of the first and the second bout. But the mean of the second bout of legs was significant smaller than the first bout (p < 0.05. For the PP variable there was no difference among the mean values to the first and second bout as much for arms as for legs. It looks like to exist larger magnitude to O2 adjustment for arms than legs, that could be associated to specific demands to which S

  11. Aferição das cargas a aplicar a nadadores no teste Wingate em cicloergómetro

    Directory of Open Access Journals (Sweden)

    Susana Maria Soares

    2013-12-01

    Full Text Available O teste Wingate parece ser o teste padrão para avaliar o potencial anaeróbio, implicando a aplicação de uma carga de resistência cujo valor é uma percentagem do peso corporal do sujeito a avaliar. O objetivo do presente estudo foi o de determinar a carga de resistência, expressa em percentagem do peso corporal, a aplicar a nadadores no teste Wingate realizado em cicloergómetro. A amostra foi constituída por sete nadadores e sete nadadoras. Para aferir a carga ótima de resistência a aplicar a cada nadador foi realizado um pré-teste de nx10s, com um intervalo de 15min entre cada repetição. A resistência aplicada em cada repetição foi de 7.5% do peso corporal, aumentada em frações de 0.5%. A carga de resistência ótima determinada no pré-teste foi aplicada no teste Wingate tal como determinada e incrementada e subtraída em 0.5% do peso corporal, tendo-se verificado uma relação não-linear entre a potência e a carga externa. A carga de resistência ótima a aplicar no teste Wingate foi superior ao valor padrão de 7.5%, quer para os nadadores (9.50 ± 0.65%, quer para as nadadoras (9.86 ± 1.18%.

  12. Effect of anaerobic bout using wingate cycle ergometer on pressure pain threshold in normal individuals

    Directory of Open Access Journals (Sweden)

    Ajit Dabholkar

    2017-01-01

    Full Text Available Introduction: Published studies reveal that incremental graded and short term anaerobic exercise lead to an increase in beta-endorphin levels, the extent correlating with the lactate concentration. Beta- endorphin can be released into the circulation from the pituitary gland or can project into areas of the brain through nerve fibers. Exercise of sufficient intensity and duration has been demonstrated to increase circulating Beta-endorphin levels. Thus, our study investigates the effect of anaerobic activity on pressure pain threshold (PPT in normal individuals. Materials and Methods: Normal individuals (N = 30 between the age group of 20-30 years were recruited for this study. The subjects performed an anaerobic bout on Monark Wingate cycle egometer. A pre and post assessment of PPT was evaluated. Data Analysis: Graphpad Instat 3 software program was used for statistical analysis. A paired't' test was done to analyse the level of statistical significance between the pre and post PPT. Results: Study revealed that post anaerobic bout there was statistical significant difference between pre and post PPT in quadriceps, Mean 14.41,95% CI[12.95,15.87], Mean 16.73,95% CI[15.06,18.40] & (P value 0.0411 and gastrocnemius,Mean 13.56, 95% CI[12.18,14.93], Mean 15.55,95% CI[13.94,17.16] & (P value <0.0001. Conclusion: The study emphasizes the influence of pain modulation after an anaerobic bout.

  13. ACUTE EFFECTS OF THREE DIFFERENT STRETCHING PROTOCOLS ON THE WINGATE TEST PERFORMANCE

    Directory of Open Access Journals (Sweden)

    Bruno L. Franco

    2012-03-01

    Full Text Available The purpose of this study was to examine the acute effects of different stretching exercises on the performance of the traditional Wingate test (WT. Fifteen male participants performed five WT; one for familiarization (FT, and the remaining four after no stretching (NS, static stretching (SS, dynamic stretching (DS, and proprioceptive neuromuscular facilitation (PNF. Stretches were targeted for the hamstrings, quadriceps, and calf muscles. Peak power (PP, mean power (MP, and the time to reach PP (TP were calculated. The MP was significantly lower when comparing the DS (7.7 ± 0.9 W/kg to the PNF (7.3 ± 0.9 W/kg condition (p < 0.05. For PP, significant differences were observed between more comparisons, with PNF stretching providing the lowest result. A consistent increase of TP was observed after all stretching exercises when compared to NS. The results suggest the type of stretching, or no stretching, should be considered by those who seek higher performance and practice sports that use maximal anaerobic power.

  14. Fatty acid composition of fat depots in wintering Canada geese

    Science.gov (United States)

    Austin, J.E.

    1993-01-01

    I determined the fatty acid composition of subcutaneous, abdominal, visceral, and leg saddle depots in adult female Canada Geese (Branta canadensis) wintering in north-central Missouri during October 1984-March 1985. Mean levels of C14:0, C16:0, C16:1, C18:0, C18:1, C18:2, and C18:3 generally were highest in the subcutaneous and abdominal depots. The ratio of saturated to unsaturated fats was highest in the leg saddle depot and lowest in the abdominal depot. I also assessed the differences among sexes, seasons, and years in fatty acid composition of abdominal fat depots in adult geese collected during October-March, 1985-1987. Adult females had consistently higher levels of C14:0 in abdominal depots than males. Fatty acid composition of the abdominal depot differed among years but not by season. In the abdominal depot, C14:0, C16:0, C16:1, and C18:1 were higher in 1986-1987 compared with the previous two years, whereas C18:3 was highest in 1984-1985. Differences among years reflected changes in winter diet. Fatty acids of wintering geese were similar to those previously found in breeding Canada Geese.

  15. Architecture Study for a Fuel Depot Supplied from Lunar Resources

    Science.gov (United States)

    Perrin, Thomas M.

    2016-01-01

    Heretofore, discussions of space fuel depots assumed the depots would be supplied from Earth. However, the confirmation of deposits of water ice at the lunar poles in 2009 suggests the possibility of supplying a space depot with liquid hydrogen/liquid oxygen produced from lunar ice. This architecture study sought to determine the optimum architecture for a fuel depot supplied from lunar resources. Four factors - the location of propellant processing (on the Moon or on the depot), the location of the depot (on the Moon, or at L1, GEO, or LEO), the location of propellant transfer (L1, GEO, or LEO), and the method of propellant transfer (bulk fuel or canister exchange) were combined to identify 18 potential architectures. Two design reference missions (DRMs) - a satellite servicing mission and a cargo mission to Mars - were used to create demand for propellants, while a third DRM - a propellant delivery mission - was used to examine supply issues. The architectures were depicted graphically in a network diagram with individual segments representing the movement of propellant from the Moon to the depot, and from the depot to the customer.

  16. Stock Funding of Depot Level Reparables: Win, Lose, or Draw?

    Science.gov (United States)

    1993-06-04

    trends Identified, Based on this analysis, it appears that the stook funiding of depot level reparables in adversely affauting •qulpmnnt availability...Deborah A. Elliot, "The Effect of Defense Management Revlow Decision 904. Stook Funding of Depot Level Reparables, on Cash Flow within the Reparable

  17. Peak Expiratory Flow Rate in Petroleum Depot Workers and Petrol ...

    African Journals Online (AJOL)

    Peak Expiratory Flow Rate (PEFR) values in litres per minute were determined in petrol depot loaders, petrol station attendants and in control subjects. The PEFR values were 315 ± 94, 386 + 91 and 529 + 94 litres/min. in depot workers, petrol attendants and control subjects respectively. The value in the control subjects ...

  18. Ligand Depot: a data warehouse for ligands bound to macromolecules.

    Science.gov (United States)

    Feng, Zukang; Chen, Li; Maddula, Himabindu; Akcan, Ozgur; Oughtred, Rose; Berman, Helen M; Westbrook, John

    2004-09-01

    Ligand Depot is an integrated data resource for finding information about small molecules bound to proteins and nucleic acids. The initial release (version 1.0, November, 2003) focuses on providing chemical and structural information for small molecules found as part of the structures deposited in the Protein Data Bank. Ligand Depot accepts keyword-based queries and also provides a graphical interface for performing chemical substructure searches. A wide variety of web resources that contain information on small molecules may also be accessed through Ligand Depot. Ligand Depot is available at http://ligand-depot.rutgers.edu/. Version 1.0 supports multiple operating systems including Windows, Unix, Linux and the Macintosh operating system. The current drawing tool works in Internet Explorer, Netscape and Mozilla on Windows, Unix and Linux.

  19. Celtic steel - an evaluation of depot finds

    Energy Technology Data Exchange (ETDEWEB)

    Presslinger, H.; Mayr, M. [Vereinigte Oesterreichische Eisen- und Stahlwerke AG (VOeST)-Alpine Industrieanlagenbau GmbH, Linz (Austria)

    2001-08-01

    In the course of archaeological excavations on the Gruendberg in Linz/Austria, several depots containing a total of 45 steel objects were discovered. These depots had been set up around 100 before Christ (BC). 25 objects were used to take samples for metallographic and microanalytical investigations. In the exercise of his trade, the Celtic smith could resort to different steel grades: non-alloyed, carbon alloyed, phosphorus alloyed. The technique applied was that of fire-forging single pieces of steel - which had previously been widened by hammering - to give flat bars showing a multi-layer structure. For workpieces with special requirements with regard both to hardness and to toughness, a number of carefully selected flat bars with differing contents of alloying metals were bonded by forge welding, which produced a compound material. Hardening by cold working as well as by torquing was already known to these Celtic craftsmen. To obtain tools with a hard edge and a tough core, cementation was used. (orig.)

  20. The effect of passive versus active recovery on power output over six repeated wingate sprints.

    Science.gov (United States)

    Lopez, Egla-Irina D; Smoliga, James M; Zavorsky, Gerald S

    2014-12-01

    The aim of this study was to examine the effect of active versus passive recovery on 6 repeated Wingate tests (30-s all-out cycling sprints on a Velotron ergometer). Fifteen healthy participants aged 29 (SD = 8) years old (body mass index = 23 [3] kg/m(2)) participated in 3 sprint interval training sessions separated by 3 to 7 days between each session during a period of 1 month. The 1st visit was familiarization to 6 cycling sprints; the 2nd and 3rd visits involved a warm-up followed by 6 30-s cycling sprints. Each sprint was followed by 4 min of passive (resting still on the ergometer) or active recovery (pedaling at 1.1 W/kg). The same recovery was used within each visit, and recovery type was randomized between visits. Active recovery resulted in a 0.6 W/kg lower peak power output in the second sprint (95% confidence interval [CI] [ - 0.2, - 0.8 W/kg], effect size = 0.50, p recovery. There was little difference between fatigue index, total work, or accumulated work between the 2 recovery conditions. Passive recovery is beneficial when only 2 sprints are completed, whereas active recovery better maintains average power output compared with passive recovery when several sprints are performed sequentially (partial eta squared between conditions for multiple sprints = .38).

  1. [SLEEP OF ELITE YOUNG ATHLETE AT THE ACADEMY FOR SPORT EXCELLENCE AT THE WINGATE INSTITUTE].

    Science.gov (United States)

    Navot Mintzer, Dalya; Shargal, Eyal; Fuxman, Yair; Wissblat, Dorit; Baharav, Anda

    2016-06-01

    Sleep duration and quality have a critical role in cognitive and athletic performances. A relationship was demonstrated between sleep deprivation, reduced performance and elevated injury risk. The recommended sleep duration for teenagers is at least 9 hours a day but most sleep less. To estimate sleep duration among elite adolescent athletes at the Academy for Sport Excellence at the Wingate Institute, by quantifying the changes after joining the academy and the relation to school performances and the usage of medical services. Data from medical records, including sleep screening questionnaires and a number of the athletes' medical appointments were analyzed. Athletes reported that sleep duration was less than recommended before joining the academy. After joining the academy the average sleep duration decreased (7.37 vs 7.7 hours, P = 0.05) and daytime sleepiness was elevated (13/24 v 11/24 Epworth-Sleepiness-Scale (ESS), P = 0.002). Correlations between changes in sleep duration and changes in school achievements before and after joining the academy were demonstrated (P = 0.027). No correlation was found between sleep duration at the academy and usage of medical services. Elite adolescent athletes do not sleep enough and are tired during the day. Reduction in sleep duration and elevation in sleepiness were observed with the transition to practice, study and life at the Academy for Sport Excellence. In accordance with previous studies, our findings showed elite young athletes are in a state of continuous sleep deprivation that interferes with their school achievements. Further research is needed to evaluate the importance of sleep duration and quality in performance for the health of young athletes.

  2. Disposal of chemical agents and munitions stored at Umatilla Depot Activity, Hermiston, Oregon

    Energy Technology Data Exchange (ETDEWEB)

    Zimmerman, G.P.; Hillsman, E.L.; Johnson, R.O.; Miller, R.L.; Patton, T.G.; Schoepfle, G.M.; Tolbert, V.R.; Feldman, D.L.; Hunsaker, D.B. Jr.; Kroodsma, R.L.; Morrissey, J.; Rickert, L.W.; Staub, W.P.; West, D.C.

    1993-02-01

    The Umatilla Depot Activity (UMDA) near Hermiston, Oregon, is one of eight US Army installations in the continental United States where lethal unitary chemical agents and munitions are stored, and where destruction of agents and munitions is proposed under the Chemical Stockpile Disposal Program (CSDP). The chemical agent inventory at UMDA consists of 11.6%, by weight, of the total US stockpile. The destruction of the stockpile is necessary to eliminate the risk to the public from continued storage and to dispose of obsolete and leaking munitions. In 1988 the US Army issued a Final Programmatic Environmental Impact Statement (FPEIS) for the CSDP that identified on-site disposal of agents and munitions as the environmentally preferred alternative (i.e., the alternative with the least potential to cause significant adverse impacts), using a method based on five measures of risk for potential human health and ecosystem/environmental effects; the effectiveness and adequacy of emergency preparedness capabilities also played a key role in the FPEIS selection methodology. In some instances, the FPEIS included generic data and assumptions that were developed to allow a consistent comparison of potential impacts among programmatic alternatives and did not include detailed conditions at each of the eight installations. The purpose of this Phase 1 report is to examine the proposed implementation of on-site disposal at UMDA in light of more recent and more detailed data than those included in the FPEIS. Specifically, this Phase 1 report is intended to either confirm or reject the validity of on-site disposal for the UMDA stockpile. Using the same computation methods as in the FPEIS, new population data were used to compute potential fatalities from hypothetical disposal accidents. Results indicate that onsite disposal is clearly preferable to either continued storage at UMDA or transportation of the UMDA stockpile to another depot for disposal.

  3. Fat Depots, Free Fatty Acids, and Dyslipidemia

    Directory of Open Access Journals (Sweden)

    Jon O. Ebbert

    2013-02-01

    Full Text Available Body fat deposition and excess free fatty acid (FFA metabolism contribute to dyslipidemia and the adverse health consequences of obesity. Individuals with upper body obesity have impaired functioning of adipocytes, the primary fatty acid storage site. Excess visceral fat is strongly associated with impaired suppression of FFA release in response to insulin, as well as with hypertriglyceridemia and low concentrations of high density lipoprotein (HDL cholesterol. High FFA concentrations can induce insulin resistance in muscle and liver. Furthermore, failure of hyperinsulinemia to normally suppress FFA is associated with impaired carbohydrate oxidation and muscle glucose storage, reduced hepatic insulin clearance and elevated triglycerides. Understanding the impact of body fat distribution on FFA metabolism and dyslipidemia is critical for determining the link between overweight and obesity and cardiovascular disease risk. In the current review, we will explore the relationship between adipose tissue, body fat depots, and FFA metabolism.

  4. Locating Depots for Capacitated Vehicle Routing

    DEFF Research Database (Denmark)

    Gørtz, Inge Li; Nagarajan, Viswanath

    2016-01-01

    depots, one for each vehicle, and compute routes for the vehicles so that all demands are satisfied and the total cost is minimized. Our main result is a constant-factor approximation algorithm for k-LocVRP. In obtaining this result, we introduce a common generalization of the k-median and minimum...... spanning tree problems (called k median forest), which might be of independent interest. We give a local-search based (3+ε)-approximation algorithm for k median forest, which leads to a (12+ε)-approximation algorithm for k-LocVRP, for any constant ε>0.......We study a location-routing problem in the context of capacitated vehicle routing. The input to the k-location capacitated vehicle routing problem (k-LocVRP) consists of a set of demand locations in a metric space and a fleet of k identical vehicles, each of capacity Q. The objective is to locate k...

  5. Examination of adipose depot-specific PPAR moieties

    International Nuclear Information System (INIS)

    Dodson, M.V.; Vierck, J.L.; Hausman, G.J.; Guan, L.L.; Fernyhough, M.E.; Poulos, S.P.; Mir, P.S.; Jiang, Z.

    2010-01-01

    Molecular mechanisms of peroxisome proliferator activated receptors (PPARs) are being defined rapidly, as illustrated by the volume of papers published. Much of the research is directed towards a clinical end-point/application; however, the non-homogeneous nature of adipose depots in laboratory animals is spurring similar research in domestic meat animals (such as beef cattle). Moreover, the size of adipose depots in meat animals remains an attractive feature for using them to obtain cells for PPAR research. Examination of meat-animal depot-specific PPAR moieties may provide novel information about adipocyte regulation that might be extrapolated to all animals.

  6. DEPOT database: Reference manual and user's guide

    Energy Technology Data Exchange (ETDEWEB)

    Clancey, P.; Logg, C.

    1991-03-01

    DEPOT has been developed to provide tracking for the Stanford Linear Collider (SLC) control system equipment. For each piece of equipment entered into the database, complete location, service, maintenance, modification, certification, and radiation exposure histories can be maintained. To facilitate data entry accuracy, efficiency, and consistency, barcoding technology has been used extensively. DEPOT has been an important tool in improving the reliability of the microsystems controlling SLC. This document describes the components of the DEPOT database, the elements in the database records, and the use of the supporting programs for entering data, searching the database, and producing reports from the information.

  7. Influence of selected phases of the menstrual cycle on performance in Special judo fitness test and Wingate test

    Directory of Open Access Journals (Sweden)

    Miloš Štefanovský

    2016-09-01

    Full Text Available Background: Several scientific papers in recent years dealt with the menstrual cycle and its impact on female sport performance. No differences have been found in aerobic performance, but the results of the studies dealing with the influence of the menstrual cycle on anaerobic performance are often controversial. Objective: The aim of this study was to verify the effect of selected phases of the menstrual cycle on anaerobic performance of judokas in the Wingate test and Special judo fitness test. Methods: The research sample was composed of 8 young female judokas (age 18.14 ± 3.44 years; body weight 63.86 ± 10.42 kg; height 165.43 ± 5.09 cm; judo practice 11.14 ± 3.13 years. The observed parameters in the Wingate test were as follows: a anaerobic peak power; b anaerobic capacity; c fatigue index; d blood lactate in the 5th minute after completing the test. In Special judo fitness test (SJFT we measured the following parameters: a number of throws in the first period; b second period; c third period; d total number of throws; e SJFT index. For the processing and evaluation of obtained data, we used the non-parametric Wilcoxon t-test and effect sizes are described by Cohen's d. Results: No significant changes have been observed in any of those parameters in the Wingate test and Special judo fitness test due to changes of menstrual phases, except of number of throws in the first 15-s period of the Special judo fitness test with better performance in luteal phase (p = .03; Cohen's d = 1.149. Conclusion: Better anaerobic performance in luteal phase could be a result of potential larger phosphocreatine and adenosine triphosphate stores, which can have a positive effect on high intensity specific judo performance.

  8. ANISOTROPY-BASED INCLINATION CORRECTION FOR THE MOENAVE FORMATION AND WINGATE SANDSTONE: IMPLICATIONS FOR COLORADO PLATEAU ROTATION

    Directory of Open Access Journals (Sweden)

    Andrea eMcCall

    2014-07-01

    Full Text Available The ~ 201 Ma paleopole for North America at the Triassic-Jurassic boundary is observed in two widely different locations; one paleopole is determined from the Mesozoic rift basins in eastern North America and the other from the Colorado Plateau in the southwestern United States. A large discrepancy in paleopole positions from these two localities has been attributed to large amounts of clockwise vertical axis rotation of the Colorado Plateau (>10º combined with inclination shallowing of the paleomagnetism. The sedimentary inclinations of the eastern North American basins have been corrected for shallowing, but the Colorado Plateau inclinations have not. Simple vertical axis rotation of the Colorado Plateau is not enough to bring the two paleopoles into agreement. This study of the Moenave and Wingate Formations was conducted to correct Colorado Plateau inclinations using their high field isothermal remanent anisotropy. The Moenave Formation and laterally equivalent Wingate Sandstone, which span the Triassic-Jurassic boundary, were sampled in southern Utah and northern Arizona. Thermal demagnetization isolated a characteristic remanence carried by hematite from 20 sites. High field (5 T isothermal remanent anisotropy indicated shallowing of the characteristic remanence with an average flattening factor of f=0.69. An inclination-corrected paleopole for the Moenave and Wingate Formations is located at 62.5˚N 69.9˚E (α95=5.5˚ and is shifted northward by 2.9˚ with respect to the uncorrected paleopole. When the inclination corrected paleopole is rotated counterclockwise 9.7º about an Euler pole local to the Colorado Plateau, it is statistically indistinguishable from the inclination-corrected paleopole from the eastern North American rift basins. Rotation of the uncorrected paleopole does not bring it into statistical agreement with rift basin paleopole, therefore an inclination shallowing correction is necessary to support rotation of the

  9. Examination of relationship between 30 second wingate test performance and spirometric respiratory functions in young adults

    Directory of Open Access Journals (Sweden)

    C Arslan

    2009-07-01

    Full Text Available Objective: This work has been planed to investigate whether the correlation between one of the important component of the sports performance spirometric respiratory function (SRF and 30 s Wingate Test (WT parameters of young adults who have different physical fitness level. Materials and Methods: This work included a total of 166 subjects those are 98 young boys (20.30±1.93 and 68 young girls (19.65±2.18. The subjects were divided into two groups namely regular exercises group (EG who make a regular exercises during 4.0±1.50 years and sedentary groups (SG. Both group’s subjects have similar age, height, weight and body mass index (BMI kg/m2. All the subjects were performed spirometric respiratory function test and WT power performance test. Statistical analyses were performed by SPSS computer program and the groups were compared to each other by using Independent Samples t test calculation and the correlation relation levels were calculated by using linear regression analysis. Results: In the view of physical peculiarities, it has not been found any difference between research groups that EG and SG (P>0.05. In the meaning of the measured spirometric respiratory functions and WT power performance, with the advantage of making regular sports, according to SG groups, the boys and girls EG groups showed differences (P<0.05. The correlational relationship between the spirometric and WT power parameters; it has been observed significant correlation between peak power (PP, mean power (MP, peak power/weight (PP/Wkg, mean power/weight (MP/Wkg form WT parameters and VC, FVC, FEV1, FEV1/FVC (% FEF25-75, PEF and MVV form respiration function (P<0.05 and P<0.001. On the other hand, it has not been found any significant correlation between WT anaerobic fatigue index (AFI % and respiratory functions (P<0.05. Conclusion: In this work, the tested spirometric respiratory functions have got an active role in the WT power parameters. It has been confirmed that

  10. Vertical Jumping Tests versus Wingate Anaerobic Test in Female Volleyball Players: The Role of Age

    Directory of Open Access Journals (Sweden)

    Pantelis Theodoros Nikolaidis

    2016-02-01

    Full Text Available Single and continuous vertical jumping tests, as well as the Wingate anaerobic test (WAnT, are commonly used to assess the short-term muscle power of female volleyball players; however, the relationship among these tests has not been studied adequately. Thus, the aim of the present study was to examine the relationship of single and continuous vertical jumps with the WAnT in female volleyball players. Seventy adolescent (age 16.0 ± 1.0 years, body mass 62.5 ± 7.1 kg, height 170.4 ± 6.1 cm, body fat 24.2% ± 4.3% and 108 adult female volleyball players (age 24.8 ± 5.2 years, body mass 66.5 ± 8.7 kg, height 173.2 ± 7.4 cm, body fat 22.0% ± 5.1% performed the squat jump (SJ, countermovement jump (CMJ, Abalakov jump (AJ, 30 s Bosco test and WAnT (peak power, Ppeak; mean power, Pmean. Mean power in the Bosco test was correlated (low to large magnitude with Pmean of the WAnT (r = 0.27, p = 0.030 in adolescents versus r = 0.56, p < 0.001 in adults. SJ, CMJ and AJ also correlated with Ppeak (0.28 ≤ r ≤ 0.46 in adolescents versus 0.58 ≤ r ≤ 0.61 in adults and with Pmean (0.43 ≤ r ≤ 0.51 versus 0.67 ≤ r ≤ 0.71, respectively of the WAnT (p < 0.05. In summary, the impact of the Bosco test and WAnT on muscle power varied, especially in the younger age group. Single jumping tests had larger correlations with WAnT in adults than in adolescent volleyball players. These findings should be taken into account by volleyball coaches and fitness trainers during the assessment of short-term muscle power of their athletes.

  11. Inventory Accuracy at the Defense Depot, Columbus, Ohio

    National Research Council Canada - National Science Library

    Lane, F

    1997-01-01

    We identified issues on the accuracy of inventory reporting for materiel stored at the Defense Depot, Columbus, Ohio during our overall audit of the inventory accounts in the FY 1996 Defense Business...

  12. Air Force Depot Maintenance: Analysis of Its Financial Operations

    National Research Council Canada - National Science Library

    1999-01-01

    The Air Force depot maintenance activity group is part of the Air Force Working Capital Fund, a revolving fund that relies on sales revenue rather than direct congressional appropriations to finance its operations...

  13. Expandable Cryogenic Tankage for On Orbit Depot Storage, Phase I

    Data.gov (United States)

    National Aeronautics and Space Administration — The proposed expandable depot storage tanks would make it possible to have an on-orbit tank larger in volume than any existing or planned launch vehicles. The size...

  14. Analysis of Light Armored Vehicle Depot Level Maintenance

    National Research Council Canada - National Science Library

    Mullins, Michael; Adams, Troy; Simms, Robert

    2005-01-01

    An analysis of Light Armored Vehicle (LAV) Depot Level Maintenance is conducted to examine the scheduled maintenance cycle and processes in order to determine potential inefficiencies related to cost or time...

  15. Radiological Final Status Survey of the Hammond Depot, Hammond, Indiana

    Energy Technology Data Exchange (ETDEWEB)

    T.J. Vitkus

    2008-04-07

    ORISE conducted extensive scoping, characterization, and final status surveys of land areas and structures at the DNSC’s Hammond Depot located in Hammond, Indiana in multiple phases during 2005, 2006 and 2007.

  16. Spatial Analysis of Depots for Advanced Biomass Processing

    Energy Technology Data Exchange (ETDEWEB)

    Hilliard, Michael R. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Brandt, Craig C. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Webb, Erin [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Sokhansanj, Shahabaddine [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Eaton, Laurence M. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Martinez Gonzalez, Maria I. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)

    2014-09-01

    The objective of this work was to perform a spatial analysis of the total feedstock cost at the conversion reactor for biomass supplied by a conventional system and an advanced system with depots to densify biomass into pellets. From these cost estimates, the conditions (feedstock cost and availability) for which advanced processing depots make it possible to achieve cost and volume targets can be identified.

  17. Army Medical Imaging System - ARMIS

    Science.gov (United States)

    1992-08-08

    Melvin P. Siedband Frank C. Grenzow Craig A. Heilman James R. Gray Huilian Zhang A ... NTtS CFA?•I " U ; J C l A t j. University of Wisconsin _. I e...Medical Imaging System - ARMIS Contract # 6.AUTHOR(S) Melvin P. Siedband James R. Gray DAMDI7-88C-8058 Frank C. Grenzow Huilian Zhang 63807A Craig A...its use is inconsistent to the people who must manage it. The consistency of the Macin- tosh operating system permits easier staff training as imaging

  18. Administration: Army Congressional Fellowship Program

    National Research Council Canada - National Science Library

    2000-01-01

    This printing publishes a new Army Regulation. This regulation presents the policies and procedures under which the Army manages the Army Congressional Fellowship Program and supplements applicable Department...

  19. Army medical imaging system: ARMIS

    International Nuclear Information System (INIS)

    Siedband, M.P.; Kramp, D.C.

    1987-01-01

    Recent advances of stimulable phosphor screens, data cards using optical storage means, and new personal computers with image processing capability have made possible the design of economical filmless medical imaging systems. The addition of communication links means that remote interpretation of images is also possible. The Army Medical Imaging System uses stimulable phosphor screens, digital readout, a small computer, an optical digital data card device, and a DIN/PACS link. Up to 200 images can be stored in the computer hard disk for rapid recall and reading by the radiologist. The computer permits image processing, annotation, insertion of text, and control of the system. Each device contains an image storage RAM and communicates with the computer via the small computer systems interface. Data compression is used to reduce the required storage capacity and transmission times of the 1-mB images. The credit card-size optical data cards replace film and can store 12 or more images. The data cards can be read on an independent viewer. The research is supported by the U.S. Army Biomedical Research and Development Laboratory

  20. Thermal Examination of an Orbiting Cryogenic Fuel Depot

    Science.gov (United States)

    Hull, Patrick V.; Canfield, Steven L.; Carrington, Connie; Fikes, John

    2002-01-01

    For many years NASA has been interested in the storage and transfer of cryogenic fuels in space. Lunar, L2 and other chemical propulsive space vehicle missions now have staged refueling needs that a fuel depot would satisfy. The depot considered is located in lower earth orbit. Many considerations must go into designing and building such a station. Multi-layer insulation systems, thermal shielding and low conductive structural supports are the principal means of protecting the system from excessive heat loss due to boiloff. This study focuses on the thermal losses associated with storing LH2 in a passively cooled fuel depot in a lower earth equatorial orbit. The corresponding examination looks at several configurations of the fuel depot. An analytical model has been developed to determine the thermal advantages and disadvantages of three different fuel depot configurations. Each of the systems consists of three Boeing rocket bodies arranged in various configurations. The first two configurations are gravity gradient stabilized while the third one is a spin-stabilized concept. Each concept was chosen for self-righting capabilities as well as the fuel settling capabilities, however the purpose of this paper is to prove which of the three concepts is the most efficient passively cooled system. The specific areas to be discussed are the heating time from the fusion temperature to the vaporization temperature and the amount of boiloff for a specific number of orbits. Each of the previous points is compared using various sun exposed surface areas of the tanks.

  1. Architecture Study for a Fuel Depot Supplied from Lunar Assets

    Science.gov (United States)

    Perrin, Thomas M.; Casler, James G.

    2016-01-01

    This architecture study sought to determine the optimum architecture for a fuel depot supplied from lunar assets. Four factors - the location of propellant processing (on the Moon or on the depot), the depot location (on the Moon, L1, GEO, or LEO), the propellant transfer location (L1, GEO, or LEO), and the propellant transfer method (bulk fuel or canister exchange) were combined to identify 18 candidate architectures. Two design reference missions (DRMs) - a commercial satellite servicing mission and a Government cargo mission to Mars - created demand for propellants, while a propellant delivery DRM examined supply issues. The study concluded Earth-Moon L1 is the best location for an orbiting depot. For all architectures, propellant boiloff was less than anticipated, and was far overshadowed by delta-v requirements and resulting fuel consumption. Bulk transfer is the most flexible for both the supplier and customer. However, since canister exchange bypasses the transfer of bulk cryogens and necessary chilldown losses, canister exchange shows promise and merits further investigation. Overall, this work indicates propellant consumption and loss is an essential factor in assessing fuel depot architectures.

  2. Medical professionals convicted of accessing child pornography--presumptive lifetime prohibition on paediatric practice? Health Care Complaints Commission v Wingate.

    Science.gov (United States)

    Shats, Kathy; Faunce, Thomas

    2008-05-01

    Health Care Complaints Commission v Wingate [2007] NSWCA 326 concerns an appeal from the New South Wales Medical Tribunal regarding its findings on professional misconduct outside the practice of medicine in relation to a doctor convicted of possessing child pornography. The latest in a number of cases on this issue in Australia, it highlights the complexity of such decisions before medical tribunals and boards, as well as the diversity of approaches taken. Considering both this case and the recent Medical Practitioners Board of Victoria case of Re Stephanopoulos [2006] MPBV 12, this column argues that Australian tribunals and medical boards may not yet have achieved the right balance here in terms of protecting public safety and the reputation of the profession as a whole. It makes the case for a position statement from Australian professional bodies to create a presumption of a lifetime prohibition on paediatric practice after a medical professional has been convicted of accessing child pornography.

  3. Pengembangan Merek dan Pengkajian Strategi Pemasaran di Depot Rasa Suka Kediri

    OpenAIRE

    Raharjo, Rini; Surjani, Rosita Meitha; Rinawiyanti, Esti Dwi

    2013-01-01

    Depot Rasa Suka is a culinary business that provides a variety of Indonesian dishes. However people still do not know and yet loyal to Depot Rasa Suka due to the unavailability of parking space, quite a long serving time, hot room, less attractive promotion and room design. Therefore Depot Rasa Suka need to devise strategies to develop brands through brand equity analysis and improvement of brand elements as well as designing a marketing strategies. The goal of this research is to make Depot ...

  4. Chemical Stockpile Disposal Program: Review and comment on the Phase 1 environmental report for the Pueblo Depot Activity, Pueblo, Colorado

    International Nuclear Information System (INIS)

    Olshansky, S.J.; Krummel, J.R.; Policastro, A.J.; McGinnis, L.D.

    1994-03-01

    As part of the Chemical Stockpile Disposal Program, an independent review is presented of the US Army Phase I environmental report for the disposal of chemical agents and munitions stored at the Pueblo Depot Activity (PUDA) in Pueblo, Colorado. The Phase I report addresses new and additional concerns not incorporated in the final programmatic environmental impact statement (FPEIS). These concerns are addressed by examining site-specific data for the PUDA. On the basis of our review of the Phase I report, we concluded that on-site meteorological data from December 1988 to June 1992 appear to be of insufficient quality to have been used instead of the off-site Pueblo airport data. No additional meteorological data have been collected since June 1992. The Phase I report briefly mentions problems with the air pollution control system. These problems will likely require the systems to be upgraded at the Johnston Atoll site and at each of the other depots in the continental United States. Without such improvements, the probability of accidents during start-up and shutdown would likely increase. The Army has a lessons-learned program to incorporate improvements into the design of future facilities. The Phase I report does not make any design change commitments. These issues need to be fully evaluated and resolved before any final conclusion concerning the adequacy of the decision in the FPEIS can be made with respect to the PUDA. With the exception of this issue, the inclusion of other more detailed site-specific data in the Phase I report does not change the decision reached in the FPEIS (which favored on-site disposal at the PUDA). We recommend that site-specific data on water, ecological, socioeconomic, and cultural resources and emergency planning and preparedness be considered explicitly in the site-specific EIS decision-making process

  5. Disposal of chemical agents and munitions stored at Umatilla Depot Activity, Hermiston, Oregon. Final Phase 1 environmental report

    Energy Technology Data Exchange (ETDEWEB)

    Zimmerman, G.P.; Hillsman, E.L.; Johnson, R.O.; Miller, R.L.; Patton, T.G.; Schoepfle, G.M.; Tolbert, V.R.; Feldman, D.L.; Hunsaker, D.B. Jr.; Kroodsma, R.L.; Morrissey, J.; Rickert, L.W.; Staub, W.P.; West, D.C.

    1993-02-01

    The Umatilla Depot Activity (UMDA) near Hermiston, Oregon, is one of eight US Army installations in the continental United States where lethal unitary chemical agents and munitions are stored, and where destruction of agents and munitions is proposed under the Chemical Stockpile Disposal Program (CSDP). The chemical agent inventory at UMDA consists of 11.6%, by weight, of the total US stockpile. The destruction of the stockpile is necessary to eliminate the risk to the public from continued storage and to dispose of obsolete and leaking munitions. In 1988 the US Army issued a Final Programmatic Environmental Impact Statement (FPEIS) for the CSDP that identified on-site disposal of agents and munitions as the environmentally preferred alternative (i.e., the alternative with the least potential to cause significant adverse impacts), using a method based on five measures of risk for potential human health and ecosystem/environmental effects; the effectiveness and adequacy of emergency preparedness capabilities also played a key role in the FPEIS selection methodology. In some instances, the FPEIS included generic data and assumptions that were developed to allow a consistent comparison of potential impacts among programmatic alternatives and did not include detailed conditions at each of the eight installations. The purpose of this Phase 1 report is to examine the proposed implementation of on-site disposal at UMDA in light of more recent and more detailed data than those included in the FPEIS. Specifically, this Phase 1 report is intended to either confirm or reject the validity of on-site disposal for the UMDA stockpile. Using the same computation methods as in the FPEIS, new population data were used to compute potential fatalities from hypothetical disposal accidents. Results indicate that onsite disposal is clearly preferable to either continued storage at UMDA or transportation of the UMDA stockpile to another depot for disposal.

  6. Computer-aided acquisition and logistics support (CALS): Concept of Operations for Depot Maintenance

    Energy Technology Data Exchange (ETDEWEB)

    Bourgeois, N.C.; Greer, D.K.

    1993-04-01

    This CALS Concept of Operations for Depot Maintenance provides the foundation strategy and the near term tactical plan for CALS implementation in the depot maintenance environment. The user requirements enumerated and the overarching architecture outlined serve as the primary framework for implementation planning. The seamless integration of depot maintenance business processes and supporting information systems with the emerging global CALS environment will be critical to the efficient realization of depot user's information requirements, and as, such will be a fundamental theme in depot implementations.

  7. Technology requirements for an orbiting fuel depot - A necessary element of a space infrastructure

    Science.gov (United States)

    Stubbs, R. M.; Corban, R. R.; Willoughby, A. J.

    1988-01-01

    Advanced planning within NASA has identified several bold space exploration initiatives. The successful implementation of these missions will require a supporting space infrastructure which would include a fuel depot, an orbiting facility to store, transfer and process large quantities of cryogenic fluids. In order to adequately plan the technology development programs required to enable the construction and operation of a fuel depot, a multidisciplinary workshop was convened to assess critical technologies and their state of maturity. Since technology requirements depend strongly on the depot design assumptions, several depot concepts are presented with their effect of criticality ratings. Over 70 depot-related technology areas are addressed.

  8. Technology requirements for an orbiting fuel depot: A necessary element of a space infrastructure

    Science.gov (United States)

    Stubbs, R. M.; Corban, R. R.; Willoughby, A. J.

    1988-01-01

    Advanced planning within NASA has identified several bold space exploration initiatives. The successful implementation of these missions will require a supporting space infrastructure which would include a fuel depot, an orbiting facility to store, transfer and process large quantities of cryogenic fluids. In order to adequately plan the technology development programs required to enable the construction and operation of a fuel depot, a multidisciplinary workshop was convened to assess critical technologies and their state of maturity. Since technology requirements depend strongly on the depot design assumptions, several depot concepts are presented with their effect on criticality ratings. Over 70 depot-related technology areas are addressed.

  9. Redistributing Stock in Library Systems with a Depot

    NARCIS (Netherlands)

    van der Heide, Gerlach; Roodbergen, Kees Jan; van Foreest, Nicky

    Public library organizations often utilize depots for carrying out shipments to libraries in case of stock-outs and for storing low demand rental items at low cost. Similar systems may be employed by rental companies for other rental products such as tools, DVDs, and jewelry. Since shipments deplete

  10. Locoregional cancer therapy using polymer-based drug depots

    NARCIS (Netherlands)

    Ramazani, F.; van Nostrum, C.F.; Storm, Gerrit; Kiessling, F.; Lammers, Twan Gerardus Gertudis Maria; Hennink, W.E.; Kok, R.J.

    2016-01-01

    Locoregional delivery of anticancer drugs is an attractive approach to minimize adverse effects associated with intravenous chemotherapy. Polymer-based drug depots injected or implanted intratumorally or adjacent to the tumor can provide long-term local drug exposure. This review highlights studies

  11. Contraception with depot medroxy progesterone acetate (DMPA) in ...

    African Journals Online (AJOL)

    Clinical experience with depot medroxy progesterone acetate (DMPA) at the family planning clinic of the University of Port Harcourt Teaching Hospital st st between 1 of January 2004 and 31 of December 2013 is presented. This was a descriptive retrospective study aimed at establishing the acceptance, safety and ...

  12. Simultaneously Recovering Rolling Stock Schedules and Depot Plans Under Disruption

    DEFF Research Database (Denmark)

    Haahr, Jørgen Thorlund; Lusby, Richard Martin; Larsen, Jesper

    2015-01-01

    In this paper we consider two important railway optimization problems. In particular, we focus on the Rolling Stock Rescheduling problem and the Depot Replanning problem, respectively. We present an integrated framework for solving these two problems simultaneously, and show that it is fast enoug...

  13. Multiple-Depot Integrated Vehicle and Crew Scheduling

    NARCIS (Netherlands)

    D. Huisman (Dennis); R. Freling (Richard); A.P.M. Wagelmans (Albert)

    2003-01-01

    textabstractThis paper presents two different models and algorithms for integrated vehicle and crew scheduling in the multiple-depot case. The algorithms are both based on a combination of column generation and Lagrangian relaxation. Furthermore, we compare those integrated approaches with each

  14. Whole tree transportation system for timber processing depots

    Science.gov (United States)

    John Lancaster; Tom Gallagher; Tim  McDonald; Dana Mitchell

    2016-01-01

    The growing demand for alternative energy has led those who are interested in producing sustainable energy from renewable timber to devise new concepts to satisfy those demands. The concept of timber processing depots, where whole stem trees will be delivered for future processing into wood products and high quality energy fuel, has led to the re-evaluation of our...

  15. Training Needs Analysis for Bus Depot Managers at GSRTC

    Science.gov (United States)

    Shah, Hardik; Gopal, Raj

    2012-01-01

    Purpose: With rapid industrialization and population growth in the urban and rural areas in India, the demand for public transport has risen sharply. In the fast changing scenario in the public transit sector, the role of a bus depot manager (DM) has also undergone substantial transformation. This paper aims to identify and gauge the…

  16. An Archeological Overview and Management Plan for Tooele Army Depot North and South

    Science.gov (United States)

    1984-03-29

    and chukar, both introduced gamebirds, sage grouse, mourning dove, black-billed magpie , common raven, and numerous species of waitrfowl and other...searching for Gunnison’ s murderers . Use of the Rush and Tooele Valleys by the military continued sporadically through the end of the Civil War (Mercer 1961...other small rodents (Fautin 1946, Durrant 1952). Common resident or breeding bird species include magpie , common crow, rock dove, common night hawk

  17. The MTA UXO Survey and Target Recovery on Lake Erie at the Former Erie Army Depot

    Science.gov (United States)

    2009-12-01

    4.3 40 3 0.118 0.4 105mm ? 6.0 14.0 40 90mm North Horizontal Sand / clay bottom -90mm APHE , unfuzed TR35-22 TRU-258 329187.06 4606840.41 4.3 45 -3... APHE , unfuzed T Horizontal Sand / clay bottom T Horizontal Sand / clay bottom T NA Hard clay, contact below 2 feet, not recover T NA Hard clay, contact...management, respiratory support (ventilator), prevention of secondary infections (pneumonia, urinary tract, etc.) and nursing care. Site Specific

  18. Community Environmental Response Facilitation Act (CERFA) Report, Sacramento Army Depot, Sacramento, California

    Science.gov (United States)

    1994-04-01

    REFER TO NAP #) Map Number: 48197R EPA ID Number: CAD983592080 Facility: BUZZ OATES ENTERPRIZES Address: 8615 ELDER CREEK RD City: SACRAMENTO Zip...pesticides such as DDT, Aldrin -Dieldrin, and the herbicide 2,4,5-T. 2. Request Office of Legal Counsel verify the exemption from CERCLA for routine

  19. Tooele Army Depot-North Area Suspected Releases SWMUs. Volume 2, Appendices A - J. Revision

    Science.gov (United States)

    1993-12-01

    e 00 .16E r oo CA96 96a > o;,> p > > dnA WS" FAa - - -~ -~ - .- - ~ - - - - - - C- C- C- - C- C- C- -C A- - a a...1 SAO 1.310 1.01 UkL sAm P/Il/OIt Gi Wtte MuSa Xf. 12.309 6.IMO E Null P/lum I ultroumm uam 12.600 9.21 UK WAS /AI/I l Cysloeule MPK Rio 2.440 2.139...standing for at least five minutes, a 26-mi portion of the extract was filtered throuh a 0.45 jun Nuclepore filter and into a 25-mi crverte, and the

  20. Tooele Army Depot Revised Final Site-Wide Ecological Risk Assessment. Volume IV.

    Science.gov (United States)

    1998-02-01

    o © Q , ©. ©. z S z z O O ig§i§§!sgi§s!is!! sissi &gs|§i © ■* © ©© — ©^ — ^ÄÄ _ QOODOODSSD299 ©z^zz^^zSS^S22©ltH...rare and/or endangered plants. The field reconnaissance to be conducted by walking or driving survey. 2. Any rare/endangered plants discovered during...Methodology used was as described in the task list. Each of the sites was visited by automobile, and the sites were surveyed by walking through the

  1. Tooele Army Depot-North Area Suspected Releases SWMUs. Phase 1 RFI report. Volume 1. Text

    Science.gov (United States)

    1993-12-01

    279 gallons of waste generated (Fisher, 1993). 5.20.1.2. The facility contains pumps, a distillation unit, a condenser, and associated equipment for...system followed by a distillation unit. The still bottoms are drummed and temporarily stored in a fenced satellite area which is a bermed concrete pad...storage tank C)Aboveground storage tank / s, 3i I - //- so ad N) K ~ ST I, IMI Ii I,006 1080 /7W 20/ omw 3 /32.3 006007 359 C012 MAITENNC ARE 1030 7600

  2. Sierra Army Depot, Phase 1, Remedial Investigation/Feasibility Study, Lassen County, California. Final Remedial Investigation

    Science.gov (United States)

    1991-10-01

    Arsenic 6.200 ug/g 29- vmr -1990 JS11 Barium 264.700 uglg 29-mar-1990 4S11 Barium 233.100 uglg 29-mar-1990 JS11 Motybdenum 2.500 uglg 29-mar-l99 4S11... sports activities such as hunting or fishing are allowed on base; 7) areas are restricted by base commander as "off limits" and 8) ambient outdoor 3

  3. Tooele Army Depot Revised Final Site-Wide Ecological Risk Assessment. Volume I.

    Science.gov (United States)

    1998-02-01

    Sambucus caerulea Family: Chenopodiaceae Atriplex canescens Atriplex confertifotia Atriplex falcata Atriplex gardneri Atriplex rosea Atriplex...Family: Malvaceae Sphaeralcea coccinea ssp. dissecta Sphaeralcea grossulariaefolia Family: Onagraceae Oenothera caespitosa Oenothera biennis Family

  4. Demonstration Testing of Plastic Media Blasting (PMB) at LetterKenny Army Depot.

    Science.gov (United States)

    1989-01-10

    particularly desirable for various types of aucomat~ed PMB equipment. 11.2 Alternativa Depaintinz Methods There are several alternative depainting methods...1988. 15. "Flashblast - The Light That Cleans," Tom Johnson, Popular Science, p.82 ff, July 1982. 14-i 16. "Flashlamp Depainting System," Final Report

  5. Case Study: Structural Evaluation of Steel Truss Aircraft Hangars at Corpus Christi Army Depot, Texas

    National Research Council Canada - National Science Library

    Al-Chaar, Ghassan

    1999-01-01

    .... Engineering analysis of such structures currently in use can identify structural vulnerabilities, and retrofit schemes may be developed to reduce or eliminate these vulnerabilities to severe wind loads...

  6. Sympathetic denervation of one white fat depot changes norepinephrine content and turnover in intact white and brown fat depots

    Science.gov (United States)

    Harris, Ruth B.S.

    2013-01-01

    It is well established that the sympathetic nervous system regulates adipocyte metabolism and recently it has been reported that sensory afferents from white fat overlap anatomically with sympathetic efferents to white fat. The studies described here characterize the response of intact fat pads to selective sympathectomy (local 6-hydroxydopamine injections) of inguinal (ING) or epididymal (EPI) fat in male NIH Swiss mice and provide in vivo evidence for communication between individual white and brown fat depots. The contralateral ING pad, both EPI pads, perirenal and mesenteric pads were significantly enlarged four weeks after denervating one ING pad, but only intrascapular brown fat (IBAT) increased when both ING pads were denervated. Denervation of one or both EPI pad had no effect on fat depot weights. In an additional experiment, NE turnover was inhibited in ING, retroperitoneal, mesenteric and IBAT two days after denervation of both EPI or of both ING pads. NE content was reduced to 10-30% of control values in all fat depots. There was no relation between early changes in NE turnover and fat pad weight 4 weeks after denervation, even though the reduction in NE content of intact fat pads was maintained. These data demonstrate that there is communication among individual fat pads, presumably through central integration of activity of sensory afferent and sympathetic efferent fibers,that changes sympathetic drive to white adipose tissue in a unified manner. In specific situations, removal of sympathetic efferents to one pad induces a compensatory enlargement of other intact depots. PMID:22513494

  7. Inflammatory characteristics of distinct abdominal adipose tissue depots relate differently to metabolic risk factors for cardiovascular disease Distinct fat depots and vascular risk factors

    NARCIS (Netherlands)

    Kranendonk, Mariette E. G.; van Herwaarden, Joost A.; Stupkova, Tereza; de Jager, Wilco; Vink, Aryan; Moll, Frans L.; Kalkhoven, Eric; Visseren, Frank L. J.

    Objective: Abdominal obesity is associated with insulin resistance and metabolic syndrome. However, specific contributions of distinct adipose tissue (AT) depots to metabolic complications of obesity are still unclear. In this study, the inflammatory profile of four distinct abdominal AT-depots and

  8. Radiological Final Status Survey of the Hammond Depot, Hammond, Indiana

    International Nuclear Information System (INIS)

    Vitkus, T.J.

    2008-01-01

    ORISE conducted extensive scoping, characterization, and final status surveys of land areas and structures at the DNSC's Hammond Depot located in Hammond, Indiana in multiple phases during 2005, 2006 and 2007. This report provides a detailed discussion of the radiological survey planning, survey implementation, remediation, and the results for these activities supporting the conclusion that radioactive contamination previously identified at the Hammond Depot (HD) has been reduced to levels such that the site may be released without radiological restrictions. The objective of the radiological final status survey (FSS) was to obtain the data necessary to demonstrate compliance with the U.S. Nuclear Regulatory Commission (NRC)-approved site-specific derived concentration guideline levels (DCGLs) for both structural surfaces and outdoor areas (ORISE 2006a and NRC 2007). The DCGLs were modeled such that any residual licensed material would not exceed the NRC's basic dose limit for license termination of 25 millirem per year (mrem/y)

  9. Complexity and Army Transformation

    Science.gov (United States)

    Calhoun, Mark T.

    On 12 Octther 1999, the U.S. Army began a journey down a new path to innovation, when General Eric Shinseki presented his vision of Army Transformation at the 45th annual meeting of the Association of the United States Army. In this speech, General Shinseki described the Army as an organization consisting of heavy forces with excellent staying power but poor strategic responsiveness, light forces with excellent responsiveness but poor staying power, and a logistics system with an excessively large footprint. His proposed solution, a comprehensive change of the Army resulting in full-spectrum dominance and strategic responsiveness, would occur so quickly as to "be unnerving to some." [Shinseki. 1999] While this prediction has turned out in some ways to be true, it is not necessarily the speed of change that is unnerving to many of the people studying Army Transformation.

  10. [Treatment of Adult Schizophrenic Patients With Depot Antipsychotics].

    Science.gov (United States)

    Jaramillo González, Luis Eduardo; Gómez Restrepo, Carlos; García Valencia, Jenny; de la Hoz Bradford, Ana María; Ávila-Guerra, Mauricio; Bohórquez Peñaranda, Adriana

    2014-01-01

    To determine the indications of long-acting antipsychotic injection and what its effectiveness and safety in adult patients with schizophrenia during the treatment maintenance phase. A clinical practice guideline was elaborated under the parameters of the Methodological Guide of the Ministerio de Salud y Protección Social to identify, synthesize and evaluate the evidence and make recommendations about the treatment and follow-up of adult patients with schizophrenia. The evidence of NICE guide 82 was adopted and updated. The evidence was presented to the Guideline Developing Group and recommendations, employing the GRADE system, were produced. The literature review shows that the evidence has moderate to low quality. 8 articles were used. The risk of relapse was lower with depot risperidone and paliperidone palmitate when compared with placebo. For the risk of hospitalizations comparing depot antipsychotics (APD) versus oral AP, the result is inconclusive. Globally the second-generation APD had a lower risk of discontinuation when compared with placebo. The second generation AP had higher risk of extrapyramidal syndromes than placebo, as in the use of antiparkinsonian. The comparison of second-generation AP injections versus placebo showed an increased risk of early weight gain. The use of depot antipsychotics in the maintenance phase of adult patients diagnosed with schizophrenia is recommended if there is no adherence to oral antipsychotics as the patient's preference. It is not recommended depot antipsychotics in the acute phase of schizophrenia in adults. Copyright © 2014 Asociación Colombiana de Psiquiatría. Publicado por Elsevier España. All rights reserved.

  11. The Home Depot Upgrades its Corporate Building Prototype

    Energy Technology Data Exchange (ETDEWEB)

    none,

    2013-03-01

    The Home Depot partnered with the Department of Energy (DOE) to develop and implement solutions to build new, low-energy buildings that are at least 50% below Standard 90.1-2007 of the American Society of Heating, Refrigerating, and Air-Conditioning Engineers (ASHRAE), the American National Standards Institute (ANSI), and the Illuminating Engineering Society of North America (IESNA) as part of DOE’s Commercial Building Partnerships (CBP) Program.

  12. Discovering the Army's Core Competencies

    National Research Council Canada - National Science Library

    Rudesheim, Frederick

    2001-01-01

    This paper seeks to answer the question, "Has the Army correctly identified its core competencies to ensure the Army can adequately respond to the national military strategy?" FM 1, The Army (Prototype Draft...

  13. Army Maintenance System Transformation

    National Research Council Canada - National Science Library

    Gilbertson, Frank V

    2006-01-01

    .... Used in conjunction with pertinent historical data and developed with Army transformation goals in mind, General Systems thinking can provide the framework for guiding maintenance transformation...

  14. Effects of acute creatine supplementation on iron homeostasis and uric acid-based antioxidant capacity of plasma after wingate test

    Directory of Open Access Journals (Sweden)

    Barros Marcelo P

    2012-06-01

    Full Text Available Abstract Background Dietary creatine has been largely used as an ergogenic aid to improve strength and athletic performance, especially in short-term and high energy-demanding anaerobic exercise. Recent findings have also suggested a possible antioxidant role for creatine in muscle tissues during exercise. Here we evaluate the effects of a 1-week regimen of 20 g/day creatine supplementation on the plasma antioxidant capacity, free and heme iron content, and uric acid and lipid peroxidation levels of young subjects (23.1 ± 5.8 years old immediately before and 5 and 60 min after the exhaustive Wingate test. Results Maximum anaerobic power was improved by acute creatine supplementation (10.5 %, but it was accompanied by a 2.4-fold increase in pro-oxidant free iron ions in the plasma. However, potential iron-driven oxidative insult was adequately counterbalanced by proportional increases in antioxidant ferric-reducing activity in plasma (FRAP, leading to unaltered lipid peroxidation levels. Interestingly, the FRAP index, found to be highly dependent on uric acid levels in the placebo group, also had an additional contribution from other circulating metabolites in creatine-fed subjects. Conclusions Our data suggest that acute creatine supplementation improved the anaerobic performance of athletes and limited short-term oxidative insults, since creatine-induced iron overload was efficiently circumvented by acquired FRAP capacity attributed to: overproduction of uric acid in energy-depleted muscles (as an end-product of purine metabolism and a powerful iron chelating agent and inherent antioxidant activity of creatine.

  15. Fatty acid composition of subcutaneous and visceral fat depots in New Zealand White rabbits

    Directory of Open Access Journals (Sweden)

    P. Y. Yonkova

    2017-09-01

    Full Text Available The aim of this study was to identify the differences in the fatty acid composition of subcutaneous and visceral fat depots in healthy New Zealand White rabbits. Twelve clinically healthy rabbits with an average weight of 3.00±0.03 kg were used. The fatty acid composition of interscapular, inguinal, pericardial, perirenal and omental fat depots was determined by gas chromatography. The palmitic (C16:0 and linoleic (C18:2 acids, followed by oleic acid (C18:1 prevailed in all fat depots. The highest percentage of palmitic acid (C16:0 was detected in subcutaneous depots: inguinal (41.05±1.80% and interscapular (38.30±0.73%, whereas the highest percentage of linoleic acid (C18:2 was found in the visceral depots: perirenal (44.26±0.96% and pericardial (42.77±1.19%. Among the saturated fatty acids, myristic (C14:0 and stearic acid (C18:0 were established in higher content in subcutaneous depots than in visceral ones. Palmitoleic acid (C16:1 content in the pericardial fat depot was 10.63±2.60%, while in the interscapular, perirenal, omental and inguinal FD it was almost twice lower (Р<0.001. In the omental depot, α-linolenic acid (C18:3 content was significantly higher only vs the interscapular depot (P<0.05. The high content of saturated fatty acids in the subcutaneous depots determined their higher atherogenic and saturation index, unlike visceral ones, where a significantly higher content of unsaturated fatty acids was reported. Differences in fatty acid composition of subcutaneous and visceral fat depots proved the specific metabolism in each of them. On the other hand, this led to differences in the nutritional value of various parts of rabbit carcass.

  16. Cellular Responses and Tissue Depots for Nanoformulated Antiretroviral Therapy.

    Directory of Open Access Journals (Sweden)

    Andrea L Martinez-Skinner

    Full Text Available Long-acting nanoformulated antiretroviral therapy (nanoART induces a range of innate immune migratory, phagocytic and secretory cell functions that perpetuate drug depots. While recycling endosomes serve as the macrophage subcellular depots, little is known of the dynamics of nanoART-cell interactions. To this end, we assessed temporal leukocyte responses, drug uptake and distribution following both intraperitoneal and intramuscular injection of nanoformulated atazanavir (nanoATV. Local inflammatory responses heralded drug distribution to peritoneal cell populations, regional lymph nodes, spleen and liver. This proceeded for three days in male Balb/c mice. NanoATV-induced changes in myeloid populations were assessed by fluorescence-activated cell sorting (FACS with CD45, CD3, CD11b, F4/80, and GR-1 antibodies. The localization of nanoATV within leukocyte cell subsets was determined by confocal microscopy. Combined FACS and ultra-performance liquid chromatography tandem mass-spectrometry assays determined nanoATV carriages by cell-based vehicles. A robust granulocyte, but not peritoneal macrophage nanoATV response paralleled zymosan A treatment. ATV levels were highest at sites of injection in peritoneal or muscle macrophages, dependent on the injection site. The spleen and liver served as nanoATV tissue depots while drug levels in lymph nodes were higher than those recorded in plasma. Dual polymer and cell labeling demonstrated a nearly exclusive drug reservoir in macrophages within the liver and spleen. Overall, nanoART induces innate immune responses coincident with rapid tissue macrophage distribution. Taken together, these works provide avenues for therapeutic development designed towards chemical eradication of human immunodeficiency viral infection.

  17. Mechanisms and Metabolic Implications of Regional Differences among Fat Depots

    Science.gov (United States)

    Zhu, Yi; Karagiannides, Iordanes; Pothoulakis, Charalabos; Jensen, Michael D.; Kirkland, James L.

    2014-01-01

    Fat distribution is closely linked to metabolic disease risk. Distribution varies with sex, genetic background, disease state, certain drugs and hormones, development, and aging. Preadipocyte replication and differentiation, developmental gene expression, susceptibility to apoptosis and cellular senescence, vascularity, inflammatory cell infiltration, and adipokine secretion vary among depots, as do fatty-acid handling and mechanisms of enlargement with positive-energy and loss with negative-energy balance. How interdepot differences in these molecular, cellular, and pathophysiological properties are related is incompletely understood. Whether fat redistribution causes metabolic disease or whether it is a marker of underlying processes that are primarily responsible is an open question. PMID:23583168

  18. Comparison of heuristic approaches for the multiple depot vehicle scheduling problem

    NARCIS (Netherlands)

    A.S. Pepin; G. Desaulniers (Guy); A. Hertz (Alain); D. Huisman (Dennis)

    2006-01-01

    textabstractGiven a set of timetabled tasks, the multi-depot vehicle scheduling problem is a well-known problem that consists of determining least-cost schedules for vehicles assigned to several depots such that each task is accomplished exactly once by a vehicle. In this paper, we propose to

  19. Adipose tissue in muscle : a novel depot similar in size to visceral adipose tissue

    NARCIS (Netherlands)

    Gallagher, Dympna; Kuznia, Patrick; Heshka, Stanley; Albu, Jeanine; Heymsfield, Steven B; Goodpaster, Bret H; Visser, Marjolein; Harris, Tamara B

    BACKGROUND: The manner in which fat depot volumes and distributions, particularly the adipose tissue (AT) between the muscles, vary by race is unknown. OBJECTIVE: The objective was to quantify a previously unstudied and novel intermuscular AT (IMAT) depot and subcutaneous AT, visceral AT (VAT), and

  20. Treating allergic rhinitis with depot-steroid injections increase risk of osteoporosis and diabetes

    DEFF Research Database (Denmark)

    Aasbjerg, Kristian; Torp-Pedersen, Christian; Vaag, Allan

    2013-01-01

    In Denmark, 23% of the adult population have allergic rhinitis. We have previously demonstrated that a majority of hay fever patients are treated with depot-steroid injections in violation of the guidelines. It has been hypothesised that 1-2 annual depot-steroid injections are not harmful...

  1. A hybrid metaheuristic algorithm for the multi-depot covering tour vehicle routing problem

    NARCIS (Netherlands)

    Allahyari, S.; Salari, M.; Vigo, D.

    2015-01-01

    We propose a generalization of themulti-depot capacitated vehicle routing problem where the assumption of visiting each customer does not hold. In this problem, called the Multi-Depot Covering Tour Vehicle Routing Problem (MDCTVRP), the demand of each customer could be satisfied in two different

  2. Modeling and Solving the Multi-depot Vehicle Routing Problem with Time Window by Considering the Flexible end Depot in Each Route

    Directory of Open Access Journals (Sweden)

    Mohammad Mirabi

    2016-11-01

    Full Text Available This paper considers the multi-depot vehicle routing problem with time window in which each vehicle starts from a depot and there is no need to return to its primary depot after serving customers. The mathematical model which is developed by new approach aims to minimizing the transportation cost including the travelled distance, the latest and the earliest arrival time penalties. Furthermore, in order to reduce the problem searching space, a novel GA clustering method is developed. Finally, Experiments are run on number problems of varying depots and time window, and customer sizes. The method is compared to two other clustering techniques, fuzzy C means (FCM and K-means algorithm. Experimental results show the robustness and effectiveness of the proposed algorithm.

  3. Measuring Customer Satisfaction of Depot Maintenance: An Analysis of Customer Satisfaction of F/A-18 Maintenance at Naval Aviation Depot North Island, CA

    National Research Council Canada - National Science Library

    Forsyth, Brian

    1997-01-01

    .... A key focus of commercial practices is delivering customer satisfaction. To this extent, it is imperative that DoD depots understand and properly measure their customer's concerns if they wish to improve their performance...

  4. Artificial immune algorithm for multi-depot vehicle scheduling problems

    Science.gov (United States)

    Wu, Zhongyi; Wang, Donggen; Xia, Linyuan; Chen, Xiaoling

    2008-10-01

    In the fast-developing logistics and supply chain management fields, one of the key problems in the decision support system is that how to arrange, for a lot of customers and suppliers, the supplier-to-customer assignment and produce a detailed supply schedule under a set of constraints. Solutions to the multi-depot vehicle scheduling problems (MDVRP) help in solving this problem in case of transportation applications. The objective of the MDVSP is to minimize the total distance covered by all vehicles, which can be considered as delivery costs or time consumption. The MDVSP is one of nondeterministic polynomial-time hard (NP-hard) problem which cannot be solved to optimality within polynomial bounded computational time. Many different approaches have been developed to tackle MDVSP, such as exact algorithm (EA), one-stage approach (OSA), two-phase heuristic method (TPHM), tabu search algorithm (TSA), genetic algorithm (GA) and hierarchical multiplex structure (HIMS). Most of the methods mentioned above are time consuming and have high risk to result in local optimum. In this paper, a new search algorithm is proposed to solve MDVSP based on Artificial Immune Systems (AIS), which are inspirited by vertebrate immune systems. The proposed AIS algorithm is tested with 30 customers and 6 vehicles located in 3 depots. Experimental results show that the artificial immune system algorithm is an effective and efficient method for solving MDVSP problems.

  5. Toward Army Maneuver Transformation

    National Research Council Canada - National Science Library

    O'Brien, Charles B

    2006-01-01

    ..., can be satisfied to form the nucleus of land domain Force Application formations. This branch will be responsive to the needs of the joint force in Unified Action by adjusting the institutional inputs to force development of Army Maneuver Forces...

  6. Army Public Service Advertising.

    Science.gov (United States)

    1982-12-01

    publicists who are ever searching for economical forums through which to communicate Army viewpoints. The majority of interview and information programs...Guard to obtain public service time on stations which normally 48 reject regular Army requests. There is evidence that National Guard publicists have... Audiovisual Agency at Norton Air Force Base where it is dubbed on a C-type audio cassette and mailed directly to eighty-four radio stations. The cost of

  7. The Institutional Army, FY1975-FY2002

    National Research Council Canada - National Science Library

    Brinkerhoff, John

    2002-01-01

    This report examines the Army's mission and functions to determine a useful way to report and analyze the Institutional Army-that part of the Army that supports the Title 10 responsibilities of the Army...

  8. Index to Army Times 1992.

    Science.gov (United States)

    1993-02-01

    shortages. Army Times; June 1, 1992; 52("): p. 22. CHEMICAL WARFARE--CLOTHING Overprotective . Army Times; July 27, 1992; 52(53): p. 49. CHEMICAL WARFARE...Army Times; Nov. 30, 1992; 53(18): p. 26. CHILD ABUSE Allowance would help keep victimized families afloat. Army Times; May 18, 1992; 52(42): p. 11... CHILD ABUSE--COMPENSATION Benefits for abuse victims OK’d. Army Times; Oct. 19, 1992; 53(12): p. 26. CHILD ABUSE--GERMANY Germany: More child abuse? Army

  9. Army aeromedical crash rates.

    Science.gov (United States)

    De Lorenzo, R A; Freid, R L; Villarin, A R

    1999-02-01

    Safety is a principal concern for everyone in aviation, including those in military and civilian aeromedical programs. The U.S. Army flies thousands of helicopter missions each year, including many aeromedical flights. The comparison between Army general and aeromedical aviation crash data provides a benchmark for establishing patterns in aeromedical safety and may be useful for similar programs examining safety profiles. To determine the crash rates of Army aeromedical rotary-wing (helicopter) programs and compare them with crash rates in Army general aviation. Retrospective review of safety data from 1987 to 1995. Crashes or mishaps are categorized into three classes: A, B, and C. Class A reflects the most serious mishap and involves loss of life or aircraft destruction, whereas classes B and C represent lesser but still significant mishaps. Crash rates are compared on a year-by-year basis and are reported as events per 100,000 flight hours. Statistical analysis was performed by the z test with Yates' correction, with significance set at p crash rate was 1.86 compared with the aeromedical rate of 2.02. The mean general class A to C crash rate was 7.37 compared with the aeromedical rate of 7.44. Between 1992 and 1995, there were 3 years when the Army aeromedical program suffered no class A mishaps. Differences between study groups are statistically significant, but they are interpreted conservatively given the very low incidence of mishaps in both groups. Both rates are comparable with published civilian mishap rates. There is a very low overall incidence of crashes in both groups. There may be no practical difference between Army general and aeromedical aviation mishap rates. Furthermore, Army crash rates are comparable with published civilian mishap rates.

  10. Couches Minces de Titanate de Baryum Par Depot Organometallique

    Science.gov (United States)

    Ousi Benomar, Wahib

    1993-01-01

    Nous avons demontre la possibilite de realiser des couches minces de titanate de baryum par depot organometallique. Les films sont obtenus apres dissolution d'organometalliques choisis dans un solvant et une cuisson a une temperature determinee par thermogravimetrie. Apres un second traitement thermique a des temperatures plus elevees, les echantillons presentent une structure polycristalline tetragonale; les cristallites sont observes par microscopie electronique a balayage. La mesure de la constante dielectrique a permis de mettre en evidence une transition de phase de la structure tetragonale a la structure cubique a une temperature d'environ 125^circC. Les mesures d'indice ont ete effectuees. On note une augmentation de l'indice de refraction des films avec la temperature indiquant une meilleure densification des films. Nous avons aussi montre qu'il etait possible d'utiliser ce materiau en tant que guide d'onde optique pour pouvoir exploiter ses proprietes electrooptiques dans l'avenir.

  11. MODELING OF HIGH STORAGE SHEET DEPOT WITH PLANT SIMULATION

    Directory of Open Access Journals (Sweden)

    Andrzej Jardzioch

    2013-03-01

    Full Text Available Manufacturing processes are becoming increasingly automated. Introduction of innovative solutions often necessitate processing very large number of signals from various devices. Correctness tests of the components configuration becomes a compiled operation requiring vast expenditure of time and knowledge. The models may be a mathematical reflection of the actual object. Many actions can be computer-assisted to varying degree. One example is construction of simulation models. These can also be simulation models developed in advanced software. The stages of creating a model may be purely random. This paper aims at a closer analysis of the simulation model based on the high storage sheet depot modeling using Plant Simulation software. The results of analysis can be used for optimization, but this stage is a separate issue.

  12. Fatty acid composition of subcutaneous and visceral fat depots in New Zealand White rabbits

    OpenAIRE

    P. Y. Yonkova; G. S. Mihaylova; S. S. Ribarski; V. Doichev; R. Dimitrov; M. G. Stefanov

    2017-01-01

    The aim of this study was to identify the differences in the fatty acid composition of subcutaneous and visceral fat depots in healthy New Zealand White rabbits. Twelve clinically healthy rabbits with an average weight of 3.00±0.03 kg were used. The fatty acid composition of interscapular, inguinal, pericardial, perirenal and omental fat depots was determined by gas chromatography. The palmitic (C16:0) and linoleic (C18:2) acids, followed by oleic acid (C18:1) prevailed in all fat depots. The...

  13. The Linehaul-Feeder Vehicle Routing Problem with Virtual Depots and Time Windows

    Directory of Open Access Journals (Sweden)

    Huey-Kuo Chen

    2011-01-01

    Full Text Available This paper addresses the linehaul-feeder vehicle routing problem with virtual depots and time windows (LFVRPTW. Small and large vehicles deliver services to customers within time constraints; small vehicles en route may reload commodities from either the physical depot or from the larger vehicle at a virtual depot before continuing onward. A two-stage solution heuristic involving Tabu search is proposed to solve this problem. The test results show that the LFVRPTW performs better than the vehicle routing problem with time windows in terms of both objective value and the number of small vehicles dispatched.

  14. The Genetics of Brown Adipocyte Induction in White Fat Depots

    Directory of Open Access Journals (Sweden)

    Leslie P. Kozak

    2011-10-01

    Full Text Available Evidence that adult humans have functional brown adipose tissue has stirred interest in the possibility that the impressive effectiveness of induction of brown adipocytes to reduce obesity in mice may be translated to the human condition. A major focus recently on the identification of signaling and transcription factor that stimulate the induction of brown adipocytes has come from transgenic and gene KO models. However, these models have created a very complex picture of the regulatory mechanisms for brown fat induction. In this review insights into the critical regulatory pathways involved in brown adipocyte induction in the retroperitoneal fat depot of mice are described from quantitative trait locus analysis of allelic variability determining Ucp1 levels and brown adipocyte induction in A/J vs B6 mice. The key observation is that recombinant genotypes, found in recombinant inbred stains and backcross and intercross progeny , show transgressive variation for Ucp1 mRNA levels. These genetic crosses also show that the levels of Ucp1 mRNA are determined by interactions that control the levels of PPARα, PGC-1α and type 2 deiodinase and that each factor is controlled by a subset of QTLs that also control Ucp1expression. These results indicate that induction of Ucp1 in the retroperitoneal fat depot involves synergy between signaling and transcription factors that vary depending upon the environmental conditions. Inherent in this model is the idea that there is a high level of redundancy that can involve any factor with the potential to influence expression of the core factors, PPARα, PGC-1a and DIO2.

  15. Transformation of the Romanian Army

    National Research Council Canada - National Science Library

    Rus, Cristian

    2006-01-01

    .... By employing the Army Force Management and the Universal Joint Task List the study examines the development of the Romanian Army's current and programmed capabilities and identifies capability gaps...

  16. The Army's Occupational Analysis Program

    National Research Council Canada - National Science Library

    1996-01-01

    .... The OA Program is to be the Army's center of excellence for job analysis and design. The program is in a transition period, adapting its procedures and methods to meet the needs of today's fast-paced Army...

  17. Index to Army Times 1989

    Science.gov (United States)

    1992-08-01

    COMPETITIONS Those winning Golden Knights. Army Times; Sept. 4, 1989; 50(4): p. 2. GOVERNMENT RENTAL HOUSING PROGRAM ( GRHP ) New housing scheme. Army...Army Times; Apr. 3, 1989; 49(34): p. 17. GRHP SEE GOVERNMENT RENTAL HOUSING PROGRAM ( GRHP ) GUIDED MISSILES Countries try to keep Leaks from going

  18. The Numerical Investigation of Temperature and Velocity Distribution in the High-Bay Depot

    Directory of Open Access Journals (Sweden)

    Xuehong Wu

    2014-07-01

    Full Text Available High-bay depot plays an important role in the storage industry. Due to large and high space of high-bay depot, it is difficult to make temperature distribution uniform, which will influence the storage time of raw materials. In this paper, the aim is to find the reasonable air supply and energy-saving method; a supply-air method of high-bay depot is investigated as an example. The results show the radius and spacing of the supply-air inlet have great influence on temperature distribution. The temperature nonuniformity coefficient of summer is smaller than that of winter. The investigated results can provide a theoretical reference for the high-bay depot design and economic operation.

  19. An Archeological Overview and Management Plan for the Pueblo Depot Activity, Pueblo County, Colorado.

    Science.gov (United States)

    1984-10-01

    Denver, CO. Rippeteau, Bruce. 1977. 5LA1115: Hackberry Springs, a Colorado Millenial Source. Office of the State Archaeologist Publication Series No 9...AD-Ai59 239 AN ARCHEOLOGICAL OVERVIEW AND MANAGEMENT PLAN FOR THE 1/2 PUEBLO DEPOT ACTIVI.(U) WOODWARD-CLYDE CONSULTANTS WALNUT CREEK CR R KNUDSON 81...7 --- Final /Report No. 19 October 1, 1984 CJ 0 An Archeological Overview and Management Plan for the Pueblo Depot Activity, Pueblo County, Colorado

  20. Differential screening identifies transcripts with depot-dependent expression in white adipose tissues

    Directory of Open Access Journals (Sweden)

    Zhou Shengli

    2008-08-01

    Full Text Available Abstract Background The co-morbidities of obesity are tied to location of excess fat in the intra-abdominal as compared to subcutaneous white adipose tissue (WAT depot. Genes distinctly expressed in WAT depots may impart depot-dependent physiological functions. To identify such genes, we prepared subtractive cDNA libraries from murine subcutaneous (SC or intra-abdominal epididymal (EP white adipocytes. Results Differential screening and qPCR validation identified 7 transcripts with 2.5-fold or greater enrichment in EP vs. SC adipocytes. Boc, a component of the hedgehog signaling pathway demonstrated highest enrichment (~12-fold in EP adipocytes. We also identified a dramatic enrichment in SC adipocytes vs. EP adipocytes and in SC WAT vs. EP WAT for transcript(s for the major urinary proteins (Mups, small secreted proteins with pheromone functions that are members of the lipocalin family. Expression of Boc and Mup transcript was further assessed in murine tissues, adipogenesis models, and obesity. qPCR analysis reveals that EP WAT is a major site of expression of Boc transcript. Furthermore, Boc transcript expression decreased in obese EP WAT with a concomitant upregulation of Boc transcript in the obese SC WAT depot. Assessment of the Boc binding partner Cdon in adipose tissue and cell fractions thereof, revealed transcript expression similar to Boc; suggestive of a role for the Boc-Cdon axis in WAT depot function. Mup transcripts were predominantly expressed in liver and in the SC and RP WAT depots and increased several thousand-fold during differentiation of primary murine preadipocytes to adipocytes. Mup transcripts were also markedly reduced in SC WAT and liver of ob/ob genetically obese mice compared to wild type. Conclusion Further assessment of WAT depot-enriched transcripts may uncover distinctions in WAT depot gene expression that illuminate the physiological impact of regional adiposity.

  1. Paliperidone palmitate three-month depot formulation: a helpful innovation with practical pitfalls.

    Science.gov (United States)

    Hope, Judith D; Keks, Nicholas A

    2018-04-01

    Paliperidone palmitate is now available as a three-month depot injection. This paper will review the pharmacokinetics, pharmacodynamics, efficacy and tolerability, as well as practical issues and pitfalls for clinicians with this innovative treatment for schizophrenia. The three-month depot formulation of paliperidone for the treatment of schizophrenia is not a new compound. The nanocrystalline structure of the three-month formulation is larger and takes longer to disperse than the one-month formulation, hence its extended depot action. As expected, it is non-inferior to one-month depot paliperidone, and superior to placebo, for the treatment of schizophrenia. The side effect profile of three-month paliperidone is identical to the one-month formulation. The relapse rate on treatment is low, and the median time to relapse after ceasing the drug is 395 days. An understanding of half-life and kinetics is crucial for clinicians using this compound, and the loading strategy is important to ensure effectiveness. There are significant challenges: ensuring timely administration and switching a three-month depot treatment to another antipsychotic may be problematic. Paliperidone palmitate three-month depot injection represents an advance for both convenience and effectiveness in the long term psychopharmacological treatment of schizophrenia.

  2. Army Sustainability Report 2010

    Science.gov (United States)

    2011-09-01

    Antonio. The buffer objectives are to protect endangered species, primarily the Golden Cheeked Warbler , through off-site mitigation, and to acquire...water projects, including solar powered and standalone water filtration systems. In 2009, the Army worked with East African Community partner nations

  3. 1998 Army Modernization Plan

    Science.gov (United States)

    1998-01-01

    System (APKWS) guided munition (to complement the Hydra -70 family of rockets and supplement HELLFIRE) to provide a lower cost, more capable means of...and confirmation of biological and chemical warfare agents and toxins . Veterinary Services The Army Veterinary Corps is the DoD executive agent for

  4. Developing the Army Pentathlete

    National Research Council Canada - National Science Library

    McElroy, Kevin

    2007-01-01

    .... How will they do it, and where will they find the personnel to fill the job?. The Army is forced to deal with insurgency in Iraq, a type of engagement they have not dedicated training to since the end of Vietnam...

  5. Differential sympathetic outflow to adipose depots is required for visceral fat loss in response to calorie restriction

    OpenAIRE

    Sipe, L M; Yang, C; Ephrem, J; Garren, E; Hirsh, J; Deppmann, C D

    2017-01-01

    The sympathetic nervous system (SNS) regulates energy homeostasis in part by governing fatty acid liberation from adipose tissue. We first examined whether SNS activity toward discrete adipose depots changes in response to a weight loss diet in mice. We found that SNS activity toward each adipose depot is unique in timing, pattern of activation, and habituation with the most dramatic contrast between visceral and subcutaneous adipose depots. Sympathetic drive toward visceral epididymal adipos...

  6. Performance Gains of Propellant Management Devices for Liquid Hydrogen Depots

    Science.gov (United States)

    Hartwig, Jason W.; McQuillen, John B.; Chato, David J.

    2013-01-01

    This paper presents background, experimental design, and preliminary experimental results for the liquid hydrogen bubble point tests conducted at the Cryogenic Components Cell 7 facility at the NASA Glenn Research Center in Cleveland, Ohio. The purpose of the test series was to investigate the parameters that affect liquid acquisition device (LAD) performance in a liquid hydrogen (LH2) propellant tank, to mitigate risk in the final design of the LAD for the Cryogenic Propellant Storage and Transfer Technology Demonstration Mission, and to provide insight into optimal LAD operation for future LH2 depots. Preliminary test results show an increase in performance and screen retention over the low reference LH2 bubble point value for a 325 2300 screen in three separate ways, thus improving fundamental LH2 LAD performance. By using a finer mesh screen, operating at a colder liquid temperature, and pressurizing with a noncondensible pressurant gas, a significant increase in margin is achieved in bubble point pressure for LH2 screen channel LADs.

  7. ATTITUDES OF SHOP FLOOR EMPLOYEES TOWARD WOMEN MANAGERS IN FUEL DEPOTS: A CASE OF THE FUEL DEPOTS IN LUBUMBASHI, DEMOCRATIC REPUBLIC OF THE CONGO

    Directory of Open Access Journals (Sweden)

    Stephen N. M. Nzuve

    2014-12-01

    Full Text Available The International Labour Organization and all organizations of human rights advocate against any form of negative attitude in employment based on gender, its terms, promotion and relations. Shop floor employees play a very important role in the daily advancement and profitability of an organisation. The purpose of this study was to establish the attitude of shop floor employees toward women managers in fuel depots in Lubumbashi, Democratic Republic of the Congo. The study adopted a descriptive survey design with the population consisting of one hundred and ninety three (193 shop floor employees. A semi structured questionnaire was used to collect primary data. In total one hundred and twenty one (121 shop floor employees responded yielding a response rate of sixty three percent (63%. The findings of this study indicate that a negative attitude toward woman managers is prevalent in the Fuel Depots of Lubumbashi, Democratic Republic of the Congo. At the fuel depots, the number of women working was less than a third of the males. In spite of this, women managers are rated higher in management qualities and are considered to be more honest, diligent, compassionate, creative and intelligent when compared to their male counterparts. The study recommends a culture change among employees in fuel depots in Lubumbashi in order to enable them perceive women as equal partners at the work place.

  8. Army Programs: Army Finance and Accounting Quality Assurance Program

    National Research Council Canada - National Science Library

    1988-01-01

    This regulation discusses the primary responsibilities of commanders and staff officers at installation and higher levels for execution of the Army Finance and Accounting Quality Assurance (QA) Program...

  9. Army Efficiency Initiatives

    Science.gov (United States)

    2011-04-28

    Service College Fellows. The views expressed in this student academic research paper are those of the author and do not reflect the official policy...this student academic research paper are those of the author and do not reflect the official policy or position of the Department of the Army...for procrastination . Nothing worries rational human beings more than the great unknown or even an element of uncertainty regarding the future. To

  10. Army Equipment Modernization Plan

    Science.gov (United States)

    2013-01-01

    Vehicle (LEMV). Provides sustainment to LEMV Airship 1 operations achieving Initial Operating Capability and fully mission capable status in OEF and...builds additional airships and configurable ISR / communications payloads. • Funded $163M in FY12 for 350 of the Gen3 Electronic Control Units for...Intelligence Package High Altitude Long Endurance ( airship ) High Band COMINT Table of Contents 59 www.g8.army.mil HBCT HCCC HEMTT HEMTT-LHS HET HF HIIDE

  11. The Army Profession: A Narrative

    Science.gov (United States)

    2013-05-23

    profile cases of alleged misconduct” were symptomatic of “a much larger issue affecting the armed forces.”9 In the Associated Press, Lolita Baldor ...of-misconduct-among-high-level-military-leaders?lite (accessed January 02, 2013). 10Lolita C. Baldor , "US Army Brigadier General Jeffrey Sinclair to...Science: An Academic Discipline." Army Magazine, no. 5 (May 2005): 14-15. Baldor , Lolita C. and Michael Biesecker. "US Army Brigadier General

  12. Distinct Adipose Depots from Mice Differentially Respond to a High-Fat, High-Salt Diet.

    Science.gov (United States)

    DeClercq, Vanessa C; Goldsby, Jennifer S; McMurray, David N; Chapkin, Robert S

    2016-06-01

    Dietary factors such as high-sodium or high-fat (HF) diets have been shown to induce a proinflammatory phenotype. However, there is limited information with respect to how microenvironments of distinct intra-abdominal adipose depots respond to the combination of a high-salt, HF diet. We tested the hypothesis that HF feeding would cause changes in distinct adipose depots, which would be further amplified by the addition of high salt to the diet. Twenty-seven male C57BL6 mice were fed an HF diet (60% of kcal from fat), an HF + high-salt diet (4% wt:wt), a control diet [low-fat (LF);10% of kcal from fat], or an LF + high-salt diet for 12 wk. The main sources of fat in the diets were corn oil and lard. Adipokines in serum and released from adipose tissue organ cultures were measured by immunoassays. QIAGEN's Ingenuity Pathway Analysis was used to perform functional analysis of the RNA-sequencing data from distinct adipose depots. Diet-induced obesity resulted in a classical inflammatory phenotype characterized by increased concentrations of circulating inflammatory mediators (38-56%) and reduced adiponectin concentrations (27%). However, high-salt feeding did not exacerbate the HF diet-induced changes in adipokines and cytokines. Leptin and interleukin-6 were differentially released from adipose depots and HF feeding impaired adiponectin and resistin secretion across all 3 depots (34-48% and 45-83%, respectively). The addition of high salt to the HF diet did not further modulate secretion in cultured adipose tissue experiments. Although gene expression data from RNA sequencing indicated a >4.3-fold upregulation of integrin αX (Itgax) with HF feeding in all 3 depots, markers of cellular function were differentially expressed in response to diet across depots. Collectively, these findings highlight the role of distinct adipose depots in mice in the development of obesity and emphasize the importance of selecting specific depots to study the effects of therapeutic

  13. Index to Army Times, 1993

    Science.gov (United States)

    1994-02-01

    13): p. 37. AH-64 (HELICOPTER)--COCKPIT CANOPY Plastic covers to shield Apaches. Army Times; Aug. 16, 1993; 54(3): p. 35. AH-64 (HELICOPTER...prepares for radical surgery . Army Times; Jan. 4, 1993; 53(23): p. 26. Reform could sound death knell for CHAMPUS. Army Times; Aug. 2, 1993; 54(1): p...p. 6. FEDERAL TORT CLAIMS ACT Court upholds malpractice ban. Army Times; Mar. 8, 1993; 53(32): p. 17. FERES DOCTRINE Court upholds malpractice ban

  14. Index to Army Times 1988

    Science.gov (United States)

    1992-08-01

    p. 7. Teams will strike at child abuse problems . Army Times; Mar. 21, 1988; 48(31): p. 27. CHILD CARE CENTERS SEE DAY CARE CENTERS CHILD MOLESTING ...COMPUTER PROGRAM LANGUAGE) Ada works well in hellfire tests. Army Times; Ju 6󈨜 48(43): p. 34. ADATS SEE AIR DEFENSE ANTITANK SYSTEM (ADATS) O3 ADOPT ...A-SCHOOL PROGRAM Adopt -a-school. Army Times; May 9, 1988; 48(39): p. 27. ADOPTION AID PROGRAM Adoption reimbursement under way. Army Times; Aug. 8

  15. Depo-Provera (depot medroxyprogesterone acetate) use after bariatric surgery.

    Science.gov (United States)

    Lam, Clarissa; Murthy, Amitasrigowri S

    2016-01-01

    In the US, obesity rates are increasing greatly. The Centers for Disease Control and Prevention estimates that 68.5% of Americans, including 63.9% of adult women older than 20 years, are overweight (body mass index between 25 kg/m 2 and 29.9 kg/m 2 ) or obese (body mass index >30 kg/m 2 ). In light of this, it is not surprising that the rates of bariatric surgery have also been increasing. When considering the metabolic changes associated with both bariatric surgery and contraceptive use, in combination with the unique medical considerations of obese women, it is indisputable that clear guidelines are needed when counseling obese patients of reproductive age after bariatric surgery. In this literature review, we focus on depot medroxyprogesterone acetate (DMPA) and the implications of its use in obese women, preweight and postweight loss following bariatric surgery. Both DMPA use and bariatric surgery are known to cause bone loss, but it is still unclear whether there is an additive effect of the two factors on bone loss and whether either of these factors directly leads to an increased risk of bone fracture. The current consensus guidelines do not impose a restriction on the use of DMPA after bariatric surgery. DMPA use is associated with weight gain, and it is unclear whether weight loss blunting occurs with the use of DMPA after bariatric surgery. Prior studies had demonstrated an association with weight gain in adolescents, and therefore, those prescribing DMPA use after bariatric surgery in adolescents should proceed with caution. Adult women do not have a similar response to the use of DMPA. DMPA use has rarely been associated with increased risk of venous thromboembolism (VTE). The obesity-associated increase in VTE should be mitigated by surgically induced weight loss. The concurrent use of DMPA in the post bariatric surgical period should not further increase the risk of VTE.

  16. Tooele Army Depot - South Area Suspected Release Units. RCRA Facility Investigation - Phase 2, for SWMUs 1, 25, and 27

    Science.gov (United States)

    1995-11-01

    Disposal Pits in SWMU 1 .................. 4-32 4.1-5 SWMU 1 Open Trench with 4.2-Inch Mortars (IDF-89) .............. 4-35 4.1-6 SWMU 1 Open Trench...Thermite (Fe2O3 + Al) with nitrate, sulfur, Incendiary Mix and binder Ml Thickener Mixed aluminum soap Incendiary (Napalm) (50% coconut oil acids...representative over the 3-week period. Total suspended particulates (TSP) and metals were collected using 4-inch diameter quartz fiber filters. The filters were

  17. Examining a Paradigm Shift in Organic Depot-Level Software Maintenance for Army Communications and Electronics Equipment

    Science.gov (United States)

    2015-05-30

    supports software and system testing using common processes for early detection of software faults and defects. • Software Acquisition Support—SEC...support required for a particular system . Question 10: Please indicate your level of agreement to the following statements: • Q10a. CECOM SEC APG is... system program manager at APG who might seek support from CERDEC in lieu of CECOM if significant challenges manifested themselves, or inconvenience

  18. Tooele Army Depot Revised Final Site-Wide Ecological Risk Assessment. Volume II (Appendices A through D)

    National Research Council Canada - National Science Library

    1998-01-01

    Partial Contents: Biological Surveys, Vegetation Species, Biological profiles, Historic Soil, Sediment Data, Hazard Quotients, Soil Sample, Qualitative Survey, WIldlife, Mammal, Community SImilarity, Vegetation Sample...

  19. Final Memorandum on Remedial-Action Objectives for Operable Units 4-10. Tooele Army Depot-North Area

    Science.gov (United States)

    1992-12-01

    aeration, bioremediation , low-temperature air stripping, vitrification, aeration, and soil washing "* Capping of contaminated soils and rerouting...such as soil vitrification or bioremediation "* Institutional controls "* No action Groundwater: "* Containment "• On-site removal, treatment, and...Endrija ketone Cis-l.3-dichlorcpropent Endosulfan sulfate Acetic acid Gamma c!.:ýýrdane Vinyl Chloride (Chlorocthene) Heptachior Cbloroethane

  20. Planning Documents Known Releases SWMUs Tooele Army Depot Tooele, Utah. Volume 1: Corrective Measures Study Work Plan

    Science.gov (United States)

    2000-02-01

    volumes of contaminated soil. Rotary kilns equipped with an afterburner, quench, and air pollution control system are the commercial incinerators most...commonly used to destroy constituents in soil. The rotary kiln is a refractory-lined, slightly inclined, rotating cylinder that serves as a combustion...width and paving with asphalt or a soil cement cover. Paving the arroyo could provide vehicle access to the interior of the landfill for inspection

  1. Tooele Army Depot Revised Final Site-Wide Ecological Risk Assessment. Volume II (Appendices A through D).

    Science.gov (United States)

    1998-02-01

    and prairie dogs . In addition to small- and medium-sized mammals, the ferruginous hawk will also feed on reptiles, insects, and small birds. Only a...valleys and grasslands, and is often found in association with prairie dog communities. The owl’s population appears to have declined across its...Name Knst Environment & Infrastructure Signature ’ö ■: ■’.. FEELD DATA FORM 1.2i\\*&^<i:.m$m#?>. QUALITATIVE SURVEY/RELATIVE ABUNDANCE

  2. Sierra Army Depot, Phase 1, Remedial Investigation/Feasibility Study, Lassen County, California. Appendices G-Q

    Science.gov (United States)

    1991-10-01

    were not reproduced by rat studies. Other cancers such as of the testicles , renal adenoma and lung adenoma have also been found in TCE testing (Maltoni...carcinogen) by the inhalation and oral routes (USEPA 1990b). Q3-1 3Lung Cancer There have been a number of epidemiological studies in humans which...indicate that chronic inhalation exposure to arsenic is associated with increased risk of lung cancer (USEPA 1984, ATSDR 1989). As with many

  3. The U.S. Army Occupational and Environmental Medicine Residency at Aberdeen Proving Ground, Maryland: 1960-1996.

    Science.gov (United States)

    Gaydos, Joel C; Mallon, Timothy M; Rice, William A

    2016-11-01

    heightened interest in environmental protection and restoration of military installations, and in the threats posed by nuclear, biological and chemical weapons. Additionally, President Reagan initiated a military buildup that brought new health risks to soldiers who would use and maintain modern equipment. Army OEM physicians were required to possess competencies in many areas, to include depots in the Army industrial base, occupational health for the soldier for exposures like carbon monoxide in armored vehicles, military unique exposures like those from chemical threat agents, and environmental medicine to assess health risks on contaminated U.S. military sites and from exposures of deployed forces. These offered interesting OEM training opportunities that challenged residents in the program and helped recruit new residents. The strength of the first Army OEM residency was that it was part of a dynamic cycle that consisted of identifying and defining Army OEM needs, training physicians to meet those needs and assigning residency graduates to positions where they would have a positive impact. This paradigm can be used as the basis for contemporary assessments of the Army's need for uniformed OEM physicians and a uniformed OEM residency program. Reprint & Copyright © 2016 Association of Military Surgeons of the U.S.

  4. Distinct developmental signatures of human abdominal and gluteal subcutaneous adipose tissue depots.

    Science.gov (United States)

    Karastergiou, Kalypso; Fried, Susan K; Xie, Hui; Lee, Mi-Jeong; Divoux, Adeline; Rosencrantz, Marcus A; Chang, R Jeffrey; Smith, Steven R

    2013-01-01

    Fat distribution differs in men and women, but in both sexes, a predominantly gluteal-femoral compared with abdominal (central) fat distribution is associated with lower metabolic risk. Differences in cellular characteristics and metabolic functions of these depots have been described, but the molecular mechanisms involved are not understood. Our objective was to identify depot- and sex-dependent differences in gene expression in human abdominal and gluteal sc adipose tissues. Abdominal and gluteal adipose tissue aspirates were obtained from 14 premenopausal women [age 27.5 ± 7.0 yr, body mass index (BMI) 27.3 ± 6.2 kg/m(2), and waist-to-hip ratio 0.82 ± 0.04] and 21 men (age 29.7±7.4 yr, BMI 27.2 ± 4.5 kg/m(2), and waist-to-hip ratio 0.91 ± 0.07) and transcriptomes were analyzed using Illumina microarrays. Expression of selected genes was determined in isolated adipocytes and stromal vascular fractions from each depot, and in in vitro cultures before and after adipogenic differentiation. A total of 284 genes were differentially expressed between the abdominal and gluteal depot, either specifically in males (n = 66) or females (n = 159) or in both sexes (n = 59). Most notably, gene ontology and pathway analysis identified homeobox genes (HOXA2, HOXA3, HOXA4, HOXA5, HOXA9, HOXB7, HOXB8, HOXC8, and IRX2) that were down-regulated in the gluteal depot in both sexes (P = 2 × 10(-10)). Conversely, HOXA10 was up-regulated in gluteal tissue and HOXC13 was detected exclusively in this depot. These differences were independent of BMI, were present in both adipocytes and stromal vascular fractions of adipose tissue, and were retained throughout in vitro differentiation. We conclude that developmentally programmed differences may contribute to the distinct phenotypic characteristics of peripheral fat.

  5. Crossfit training changes brain-derived neurotrophic factor and irisin levels at rest, after wingate and progressive tests, and improves aerobic capacity and body composition of young physically active men and women.

    Science.gov (United States)

    Murawska-Cialowicz, E; Wojna, J; Zuwala-Jagiello, J

    2015-12-01

    Brain-derived neurotrophic factor (BDNF) is a protein that stimulates processes of neurogenesis, the survival of neurons and microglia, stimulates neuroplasticity, and takes part in the differentiation of cells developed in the hippocampus. BDNF is also released from skeletal muscles during exercise and can facilitate cross-talk between the nervous and muscular system. Irisin, the exercise hormone, is also released from skeletal muscles and is involved in oxidation processes in the organism. It is a vital issue from the point of view of prophylaxis and treatment through exercise of age-related diseases (e.g. senile dementia), obesity, type-2 diabetes. The aim of the study was to assess the changes in BDNF and irisin levels in young people after a 3-month CrossFit training program. At baseline and after the training, levels of BDNF and irisin were assayed before and after Wingate and progressive tests. Physical performance, body mass and composition, and muscle circumferences were also measured. There were noted: an improvement in aerobic capacity, an increase in VO2max, a reduction in adipose tissue percentage in women and an increase in LBM in all subjects. After CrossFit training the resting BDNF level increased significantly in all subjects while the resting level of irisin decreased in women, without changes in men. The resting level of BDNF at baseline was higher in men than in women. At baseline we observed an increased level of BDNF in women after Wingate and progressive tests, but in men only after the progressive test. After 3 months of CrossFit training the level of BDNF increased in all subjects, and also was higher in men than in women. In women we did not observe significant differences after both tests in comparison to rest. After the training BDNF was lower in men after Wingate and progressive tests than at rest. At baseline irisin level decreased in women after the Wingate and progressive tests. Changes in men were not observed after both tests

  6. A fluorescence-based assay for octreotide in kinetic release from depot formulations

    Directory of Open Access Journals (Sweden)

    Luiz Henrique Guerreiro

    2012-01-01

    Full Text Available Here we report the validation of a derivatization method that makes use of fluorescamine as a selective reactant for the quantitative analysis of peptide and protein drugs in the dissolution profile from depot formulations. Typical current methods require separation of the nano/microparticles and time-consuming chromatographic runs. In this study we report a method which can be conducted without the need for complete physical separation of the particles or removal of the unreacted probe. This method was used here for the analysis of the release profile of octreotide in a depot formulation, with results in excellent agreement with reported chromatographic assays.

  7. Depo-Provera (depot medroxyprogesterone acetate use after bariatric surgery

    Directory of Open Access Journals (Sweden)

    Lam C

    2016-09-01

    Full Text Available Clarissa Lam,1 Amitasrigowri S Murthy2,3 1New York University School of Medicine, 2Department of Obstetrics and Gynecology, Bellevue Hospital Center, New York University School of Medicine, 3New York University Langone Medical Center, New York, NY, USA Abstract: In the US, obesity rates are increasing greatly. The Centers for Disease Control and Prevention estimates that 68.5% of Americans, including 63.9% of adult women older than 20 years, are overweight (body mass index between 25 kg/m2 and 29.9 kg/m2 or obese (body mass index >30 kg/m2. In light of this, it is not surprising that the rates of bariatric surgery have also been increasing. When considering the metabolic changes associated with both bariatric surgery and contraceptive use, in combination with the unique medical considerations of obese women, it is indisputable that clear guidelines are needed when counseling obese patients of reproductive age after bariatric surgery. In this literature review, we focus on depot medroxyprogesterone acetate (DMPA and the implications of its use in obese women, preweight and postweight loss following bariatric surgery. Both DMPA use and bariatric surgery are known to cause bone loss, but it is still unclear whether there is an additive effect of the two factors on bone loss and whether either of these factors directly leads to an increased risk of bone fracture. The current consensus guidelines do not impose a restriction on the use of DMPA after bariatric surgery. DMPA use is associated with weight gain, and it is unclear whether weight loss blunting occurs with the use of DMPA after bariatric surgery. Prior studies had demonstrated an association with weight gain in adolescents, and therefore, those prescribing DMPA use after bariatric surgery in adolescents should proceed with caution. Adult women do not have a similar response to the use of DMPA. DMPA use has rarely been associated with increased risk of venous thromboembolism (VTE. The

  8. Male bovine GH transgenic mice have decreased adiposity with an adipose depot-specific increase in immune cell populations.

    Science.gov (United States)

    Benencia, Fabian; Harshman, Stephanie; Duran-Ortiz, Silvana; Lubbers, Ellen R; List, Edward O; Householder, Lara; Al-Naeeli, Mawadda; Liang, Xiaoyu; Welch, Lonnie; Kopchick, John J; Berryman, Darlene E

    2015-05-01

    White adipose tissue (WAT) is composed of mature adipocytes and a stromal vascular fraction (SVF), which contains a variety of cells, including immune cells that vary among the different WAT depots. Growth hormone (GH) impacts immune function and adiposity in an adipose depot-specific manner. However, its effects on WAT immune cell populations remain unstudied. Bovine GH transgenic (bGH) mice are commonly used to study the in vivo effects of GH. These giant mice have an excess of GH action, impaired glucose metabolism, decreased adiposity, increased lean mass, and a shortened lifespan. Therefore, the purpose of this study was to characterize the WAT depot-specific differences in immune cell populations in the presence of excess GH in vivo. Three WAT depots were assessed: inguinal (sc), epididymal (EPI), and mesenteric (MES). Subcutaneous and MES bGH WAT depots showed a significantly higher number of total SVF cells, yet only MES bGH WAT had higher leukocyte counts compared with control samples. By means of flow cytometry analysis of the SVF, we detected greater macrophage and regulatory T-cell infiltration in sc and MES bGH WAT depots compared with controls. However, no differences were observed in the EPI WAT depot. RNA-sequencing confirmed significant alterations in pathways related to T-cell infiltration and activation in the sc depot with fewer significant changes in the EPI bGH WAT depot. These findings collectively point to a previously unrecognized role for GH in influencing the distribution of WAT immune cell populations in a depot-specific manner.

  9. Multicenter clinical trial of leuprolide acetate depot (Luphere depot 3.75 mg for efficacy and safety in girls with central precocious puberty

    Directory of Open Access Journals (Sweden)

    You Jin Kim

    2013-12-01

    Full Text Available PurposeWe evaluated the efficacy, safety and psychological aspect of monthly administrations of the gonadotropin-releasing hormone agonists (GnRHa, leuprolide acetate depot (Luphere depot 3.75 mg, in patients with precocious puberty.MethodsA total of 54 girls with central precocious puberty were administered with leuprolide acetate (Luphere depot 3.75 mg every four weeks over 24 weeks. We evaluated the percentage of children exhibiting a suppressed luteinizing hormone (LH response to GnRH (LH peak≤3 IU/L, peak LH/follicle stimulating hormone (FSH ratio of GnRH stimulation test less than 1, change in bone age/chronologic age ratio, change in the Tanner stage and change in eating habit and psychological aspect.Results(1 The percentage of children exhibiting a suppressed LH response to GnRH, defined as an LH peak≤3 IU/L at 24 weeks was 96.3 % (52/54. (2 The percentage of children exhibiting peak LH/FSH ratio<1 at 24 weeks of the study was 94.4 % (51/54. (3 The ratio of bone age and chronological age significantly declined from 1.27±0.07 to 1.24±0.01 after the 6 months of the study. (4 The mean Tanner stage manifested a significant change 2.3±0.48 at baseline, down to 1.70±0.61 at 24 weeks. (5 Based on the questionnaires, the score for eating habits showed a significant change from the baseline 34.0±6.8 to 31.3±6.8. (6 The psychological assessment did not exhibit a significant difference except with scores for sociability, problem behavior total score and other problems.ConclusionThe leuprolide 3.75 mg (Luphere depot is useful and safety for treating children with central precocious puberty.

  10. 76 FR 66282 - Army Educational Advisory Committee

    Science.gov (United States)

    2011-10-26

    ... Committee: U.S. Army War College Subcommittee of the Army Education Advisory Committee. Dates of Meeting: November 15, 2011. Place of Meeting: U.S. Army War College, 122 Forbes Avenue, Carlisle, PA, Command... issues and matters related to the continued growth and development of the United States Army War College...

  11. 76 FR 72914 - Army Educational Advisory Committee

    Science.gov (United States)

    2011-11-28

    ...: U.S. Army War College Subcommittee of the Army Education Advisory Committee. Dates of Meeting: December 14, 2011. Place of Meeting: U.S. Army War College, 122 Forbes Avenue, Carlisle, PA, Command... issues and matters related to the continued growth and development of the United States Army War College...

  12. The effect of 10 days of intermittent fasting on Wingate anaerobic power and prolonged high-intensity time-to-exhaustion cycling performance.

    Science.gov (United States)

    Naharudin, Mohamed Nashrudin Bin; Yusof, Ashril

    2018-02-27

    Many physically active individuals have undertaken intermittent fasting to reduce their daily caloric intake. However, abstaining from meals for a specific length of time may lead to the acute disturbance of highly carbohydrate-dependent exercise performance. The purpose of this study was to observe the effect of 10 days of intermittent fasting on high-intensity type exercises, Wingate anaerobic (WT) and prolonged high-intensity time-to-exhaustion (HIT) cycling test. Twenty participants were randomised into an intermittent fasting (FAS) and a control group (CON). One day after baseline data collection on Day-0 where participants consumed their recommended daily caloric intake (FAS = 2500 ± 143 kcal day -1 ; CON = 2492 ± 20 kcal day -1 ) served over a course of five meals, the FAS group consumed only four meals where 40% was restricted by the omission of lunch (FAS = 1500 ± 55 kcal day -1 ). This diet was then continued for 10 days. Data on exercise performance and other dependent variables were collected on Day-2, -4, -6, -8 and -10. A reduction in WT power in the FAS group was observed on Day-2 (821.74 ± 66.07 W) compared to Day-0 (847.63 ± 95.94 W) with a moderate effect size (p intermittent fasting must exceed 10 days to ensure that high-intensity performance does not deteriorate because this length of time seems to be required for effective adaptation to the new dietary regimen.

  13. Effects of Creatine and Sodium Bicarbonate Coingestion on Multiple Indices of Mechanical Power Output During Repeated Wingate Tests in Trained Men.

    Science.gov (United States)

    Griffen, Corbin; Rogerson, David; Ranchordas, Mayur; Ruddock, Alan

    2015-06-01

    This study investigated the effects of creatine and sodium bicarbonate coingestion on mechanical power during repeated sprints. Nine well-trained men (age = 21.6 ± 0.9 yr, stature = 1.82 ± 0.05 m, body mass = 80.1 ±12.8 kg) participated in a double-blind, placebo-controlled, counterbalanced, crossover study using six 10-s repeated Wingate tests. Participants ingested either a placebo (0.5 g·kg(-1) of maltodextrin), 20 g·d(-1) of creatine monohydrate + placebo, 0.3 g·kg(-1) of sodium bicarbonate + placebo, or coingestion + placebo for 7 days, with a 7-day washout between conditions. Participants were randomized into two groups with a differential counterbalanced order. Creatine conditions were ordered first and last. Indices of mechanical power output (W), total work (J) and fatigue index (W·s(-1)) were measured during each test and analyzed using the magnitude of differences between groups in relation to the smallest worthwhile change in performance. Compared with placebo, both creatine (effect size (ES) = 0.37-0.83) and sodium bicarbonate (ES = 0.22-0.46) reported meaningful improvements on indices of mechanical power output. Coingestion provided small meaningful improvements on indices of mechanical power output (W) compared with sodium bicarbonate (ES = 0.28-0.41), but not when compared with creatine (ES = -0.21-0.14). Coingestion provided a small meaningful improvement in total work (J; ES = 0.24) compared with creatine. Fatigue index (W·s(-1)) was impaired in all conditions compared with placebo. In conclusion, there was no meaningful additive effect of creatine and sodium bicarbonate coingestion on mechanical power during repeated sprints.

  14. Pharmacodynamic effects of depot-medroxyprogesterone acetate (DMPA) administered to lactating women on their male infants

    NARCIS (Netherlands)

    Virutamasen, P; Leepipatpaiboon, S; Kriengsinyot, R; Vichaidith, P; Muia, PN; SekaddeKigondu, CB; Mati, JKG; Forest, MG; Dikkeschei, LD; Wolthers, BG; dArcangues, C

    Normal postpartum women, who had a spontaneous vaginal delivery of one full-term male infant, free of congenital abnormalities and other diseases, were recruited for this study. Thirteen women received 150 mg depot-medroxyprogesterone acetate (DMPA), intramuscularly on days 42 + 1 and 126 + 1

  15. Intrinsic differences in adipocyte precursor cells from different white fat depots

    DEFF Research Database (Denmark)

    Macotela, Yazmín; Emanuelli, Brice; Mori, Marcelo A

    2012-01-01

    Obesity and body fat distribution are important risk factors for the development of type 2 diabetes and metabolic syndrome. Evidence has accumulated that this risk is related to intrinsic differences in behavior of adipocytes in different fat depots. In the current study, we demonstrate that adip......, differentiation properties, and responses to environmental/genetic factors. Regulation of these populations may provide a new target for the treatment and prevention of obesity and its metabolic complications.......Obesity and body fat distribution are important risk factors for the development of type 2 diabetes and metabolic syndrome. Evidence has accumulated that this risk is related to intrinsic differences in behavior of adipocytes in different fat depots. In the current study, we demonstrate...... is higher in obesity-prone C57BL/6 mice than obesity-resistant 129 mice, and the number in both depots is increased by up to 270% by exposure of mice to high-fat diet. Thus, APCs from visceral and subcutaneous depots are dynamic populations, which have intrinsic differences in gene expression...

  16. D:epot Medroxyprogesterone Acetate (Depo-Provlera) as a Contrac ...

    African Journals Online (AJOL)

    1971-07-17

    Jul 17, 1971 ... Experience with depot medroxyprogesterone acetate as a contraceptive preparation in 7335 patients for a total of. 38 714 months over a 3-year period is described. The discontinuation rate was 18'3% and the failure rate 0'35 per 100 women-years of use. This compares very well with all other methods of ...

  17. Population Pharmacokinetic Modeling of a Subcutaneous Depot for GnRH Antagonist Degarelix

    DEFF Research Database (Denmark)

    Tornøe, Christoffer Wenzel; Agersø, Henrik; Nielsen, Henrik Aalborg

    2004-01-01

    Purpose. The objective of this study is to develop a population pharmacokinetic (PK) model that describes the subcutaneous (SC) depot formation of gonadotropin-releasing hormone ( GnRH) antagonist degarelix, which is being developed for treatment of prostate cancer, exhibiting dose-volume and dose...

  18. Population pharmacokinetic modeling of a subcutaneous depot for GnRH antagonist degarelix

    DEFF Research Database (Denmark)

    Tornøe, Christoffer Wenzel; Agersø, Henrik; Nielsen, Henrik Aalborg

    Purpose. The objective of this study is to develop a population pharmacokinetic (PK) model that describes the subcutaneous (SC) depot formation of gonadotropin-releasing hormone (GnRH) antagonist degarelix, which is being developed for treatment of prostate cancer, exhibiting dose-volume and dose...

  19. Fatty acid profile of three adipose depots in seven Spanish breeds of suckling kids.

    Science.gov (United States)

    Horcada, A; Ripoll, G; Alcalde, M J; Sañudo, C; Teixeira, A; Panea, B

    2012-10-01

    Intramuscular, subcutaneous and kidney knob fat depot fatty acid profiles were studied in 104 male suckling kids from seven Spanish breeds: Blanca Andaluza, Blanca Celtibérica, Moncaína, Negra Serrana-Castiza, Pirenaica, Malagueña and Murciano-Granadina. Kids were raised in the traditional production system on mother's milk and slaughtered at around 7kg live weight. Differences were observed between dairy (Malagueña) and meat breeds (Blanca Andaluza, Blanca Celtibérica, Moncaína, Negra Serrana-Castiza, and Pirenaica). Malagueña showed higher monounsaturated and conjugated linoleic fatty acid levels than the other breeds. Highest percentages of saturated fatty acids were observed in meat breeds. For intramuscular fat depot, the range for desirable fatty acids was 66.16-72.27% was. The influence of breed on fatty acid profiles of intramuscular, subcutaneous and kidney knob fat depots studied was evident. Intramuscular fat depot is proposed as a differentiating factor between dairy and meat breed goat kids, but not between meat breed kids. Copyright © 2012 Elsevier Ltd. All rights reserved.

  20. Clay Nanoparticles Elicit Long-Term Immune Responses by Forming Biodegradable Depots for Sustained Antigen Stimulation.

    Science.gov (United States)

    Chen, Weiyu; Zuo, Huali; Li, Bei; Duan, Chengcheng; Rolfe, Barbara; Zhang, Bing; Mahony, Timothy J; Xu, Zhi Ping

    2018-04-14

    Nanomaterials have been widely tested as new generation vaccine adjuvants, but few evoke efficient immunoreactions. Clay nanoparticles, for example, layered double hydroxide (LDH) and hectorite (HEC) nanoparticles, have shown their potent adjuvanticity in generating effective and durable immune responses. However, the mechanism by which clay nanoadjuvants stimulate the immune system is not well understood. Here, it is demonstrated that LDH and HEC-antigen complexes form loose agglomerates in culture medium/serum. They also form nodules with loose structures in tissue after subcutaneous injection, where they act as a depot for up to 35 d. More importantly, clay nanoparticles actively and continuously recruit immune cells into the depot for up to one month, and stimulate stronger immune responses than FDA-approved adjuvants, Alum and QuilA. Sustained antigen release is also observed in clay nanoparticle depots, with 50-60% antigen released after 35 d. In contrast, Alum-antigen complexes show minimal antigen release from the depot. Importantly, LDH and HEC are more effective than QuilA and Alum in promoting memory T-cell proliferation. These findings suggest that both clay nanoadjuvants can serve as active vaccine platforms for sustained and potent immune responses. © 2018 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  1. Fatty acid composition of beef steers as affected by diet and fat depot

    African Journals Online (AJOL)

    Mapiye, C, Dr

    2015-10-09

    Oct 9, 2015 ... BHP composition of beef products should therefore include feeding designer diets and exploiting fat depot ..... performance and meat quality may therefore include feeding SS and 15% DDGS in forage-based diets and ... Eds: Hobson, P.N. & Stewart, C.S., Academic and Professional, London, UK. pp.

  2. 33 CFR 334.1244 - Puget Sound, Manchester Fuel Depot, Manchester, Washington; naval restricted area.

    Science.gov (United States)

    2010-07-01

    ... northern shoreline of the Manchester Fuel Depot at latitude 47°33′55″ North, longitude 122°31′55″, West... lights, which are mounted on poles at the end of the main fuel pier on the south side of Orchard Point at...

  3. Inoculation of weaned pigs with E. coli reduces depots of vitamin E

    DEFF Research Database (Denmark)

    Lauridsen, Charlotte; Vestergaard, Ellen-Margrethe; Højsgaard, Søren

    2011-01-01

    This study was designed to investigate the effect of vitamin E supplementation on vitamin E depots and immune responses in weaned pigs after an E. coli inoculation. The design was a 2 × 2 factorial with vitamin E supplementation (150 mg/kg RRR-α-tocopheryl acetate versus a control diet containing...

  4. Design of PLGA-based depot delivery systems for biopharmaceuticals prepared by spray drying

    DEFF Research Database (Denmark)

    Wan, Feng; Yang, Mingshi

    2016-01-01

    , a one-step, continuous microencapsulation process, for manufacturing of PLGA-based depot microparticle systems with a focus on the recent efforts on understanding of the role of nozzle design in the microencapsulation of proteins/peptides, and the effect of critical solvent properties and process...

  5. Inflammation and race and gender differences in computerized tomography-measured adipose depots

    NARCIS (Netherlands)

    Beasley, L.E.; Koster, A.; Newman, A.B.; Javaid, M.K.; Ferucci, L.; Kritchevsky, S.B.; Kuller, L.H.; Pahor, M.; Visser, M.; Rubin, S.M.; Goodpaster, B.H.; Everhart, J.E.; Harris, T.B.

    2009-01-01

    A growing body of evidence has consistently shown a correlation between obesity and chronic subclinical inflammation. It is unclear whether the size of specific adipose depots is more closely associated with concentrations of inflammatory markers than overall adiposity. This study investigated the

  6. 76 FR 56406 - Science and Technology Reinvention Laboratory Demonstration Project; Department of the Army; Army...

    Science.gov (United States)

    2011-09-13

    ... DEPARTMENT OF DEFENSE Office of the Secretary Science and Technology Reinvention Laboratory Demonstration Project; Department of the Army; Army Research, Development and Engineering Command; Tank... Berry, U. S. Army Tank Automotive Research, Development and Engineering Center (TARDEC), 6501 East 11...

  7. Nanosized sustained-release drug depots fabricated using modified tri-axial electrospinning.

    Science.gov (United States)

    Yang, Guang-Zhi; Li, Jiao-Jiao; Yu, Deng-Guang; He, Mei-Feng; Yang, Jun-He; Williams, Gareth R

    2017-04-15

    Nanoscale drug depots, comprising a drug reservoir surrounded by a carrier membrane, are much sought after in contemporary pharmaceutical research. Using cellulose acetate (CA) as a filament-forming polymeric matrix and ferulic acid (FA) as a model drug, nanoscale drug depots in the form of core-shell fibers were designed and fabricated using a modified tri-axial electrospinning process. This employed a solvent mixture as the outer working fluid, as a result of which a robust and continuous preparation process could be achieved. The fiber-based depots had a linear morphology, smooth surfaces, and an average diameter of 0.62±0.07μm. Electron microscopy data showed them to have clear core-shell structures, with the FA encapsulated inside a CA shell. X-ray diffraction and IR spectroscopy results verified that FA was present in the crystalline physical form. In vitro dissolution tests revealed that the fibers were able to provide close to zero-order release over 36h, with no initial burst release and minimal tailing-off. The release properties of the depot systems were much improved over monolithic CA/FA fibers, which exhibited a significant burst release and also considerable tailing-off at the end of the release experiment. Here we thus demonstrate the concept of using modified tri-axial electrospinning to design and develop new types of heterogeneous nanoscale biomaterials. Nanoscale drug depots with a drug reservoir surrounded by a carrier are highly attractive in biomedicine. A cellulose acetate based drug depot was investigated in detail, starting with the design of the nanostructure, and moving through its fabrication using a modified tri-axial electrospinning process and a series of characterizations. The core-shell fiber-based drug depots can provide a more sustained release profile with no initial burst effect and less tailing-off than equivalent monolithic drug-loaded fibers. The drug release mechanisms are also distinct in the two systems. This proof

  8. Implementation of Geographical Information System for Bacteriological Contamination Analysis on Refill Drinking Water Depot (Study in Tembalang District)

    Science.gov (United States)

    Rahmitha, Amelia; Utami, Endang Sri; Sitohang, Marya Yenita

    2018-02-01

    People used refilled-drinking-water for household and food stall because its efficient and low cost. Based on Indonesian Health Ministry regulation, it should not have any coliform bacteria. This study aimed to describe the bacteriological contamination of refilled drinking water using geographical information system (GIS). In this research, it was used an analytic observational method. The samples were from all available (37) depots in Tembalang district, one form each depot took used a sterile bottle. Contamination of bacteria was identified by Most Probable Number (MPN) method lactose broth media, Mac Conkey media, and IMVIC media. The depot samples were then plotted on (GIS). This study showed 95% samples were not feasible to consume since they contamined coliform. All sub-district had one that contaminated by coliform, 75% sub-districts had depots that contaminated Escherichia coli, while 55% sub-districts had depots that contaminated with other bacteria. The internal risk factors of the contamination were the absence of hygiene-sanitation worthy certificate (95%), depots location near to pollution sources (5%), and the misused of UV light. The external risk factor was lack of quality control that was not as the sterilization from office health Semarang city. Policy reinforcement should be done to all of the depots.

  9. Christian Contributions to Army Values

    National Research Council Canada - National Science Library

    D'Emma, Gregory

    2000-01-01

    .... The Army trains the soldier's body through physical training and combining arms training events designed to build physical strength and endurance so that the soldier will be physically capable...

  10. Social Structures Affecting Army Performance

    National Research Council Canada - National Science Library

    Segal, David R

    2007-01-01

    The Center for Research on Military Organization undertook a multi-year research program on the impact of social change on the performance of Army units and of Soldiers after the end of the Cold War...

  11. Lessons from Army System Developments

    National Research Council Canada - National Science Library

    Lucas, William A; Rhoades, Richard G

    2007-01-01

    This paper documents the results of a multi-year Army Materiel Command-sponsored research project which employed a structured case study approach to examine the history and processes that had resulted...

  12. Racial Extremism in the Army

    National Research Council Canada - National Science Library

    Hudson, Walter M

    1998-01-01

    ... modem phenomenon of "skinheads." I then discuss the history of white supremacist extremism in the Army, culminating in the December, 1995 murders of two black civilians by soldiers assigned to the 82d Airborne Division at Fort Bragg, North Carolina...

  13. Transforming the Army Sustaining Base

    National Research Council Canada - National Science Library

    Nobles, Danny

    2000-01-01

    The Army has embarked on its transformation venture. The goal is to provide an agile, but lethal force that is capable of rapid deployment to any area of the world where America's interests are threatened...

  14. The Army's Distribution of Labor: New Force Structure and Missions for the Army National Guard

    National Research Council Canada - National Science Library

    Roberson, Melvin

    1997-01-01

    This Strategy Research Project recommends a new Army National Guard (ARNG) force structure which will successfully accomplish current missions and serve the Total Army's requirements for the future...

  15. Department of Defense Materiel Distribution System Study. Volume 3, Book 5. Appendix D-3. Depot Cost and Capacity

    Science.gov (United States)

    1978-07-01

    maintenance interface. 2> Variable Cost a. Standard Depot Cost (1) The result of joining the historical depot cost and workload daca as described...79 4 100 50 SO 100 source: „,,«„ StU(Jy Group daca cau respQnse Oepot-specific responses weighted by shipment cub e per depot. V...of floor area which must be dedicated to the travel path, and the necessity for keeping this path clear of standing objects at all ’:i:r..;S. 6.61

  16. How to Build Democratic Armies

    Science.gov (United States)

    2011-12-01

    influence is also considerable in the postcolonial and post–civil war settings, but in the others the project of building demo- cratic armies is usually...Germany, yemen, South Africa table. external influence is considerable in postcolonial and post–civil war settings, but in the others building...Most often, postcolonial armies are not built from scratch but are built on the foundations of the armed forces left behind by the colonial power

  17. Financial Reporting Procedures for Defense Distribution Depots - Defense Logistics Agency Business Area of the Defense Business Operations Fund

    National Research Council Canada - National Science Library

    Young, Shelton

    1994-01-01

    In our audit of the FY 1993 Financial Statements for the Distribution Depots--Defense Logistics Agency Business Mea of the Defense Business Operations Fund, we evaluated procedures and controls used...

  18. To Ensure the Integrity of the Cryogenic Propellant Depot Tank Within the Expected Radiation and Space Debris Environment Project

    Data.gov (United States)

    National Aeronautics and Space Administration — We intend to develop the technology for lightweight composite structure suitable for both cryogenic fuel depot storage as well as human in-space habitat. These will...

  19. Maternal obesity programs increased leptin gene expression in rat male offspring via epigenetic modifications in a depot-specific manner

    Directory of Open Access Journals (Sweden)

    Simon Lecoutre

    2017-08-01

    Conclusions: Consistent with the DOHaD hypothesis, persistent epigenetic remodeling occurs at regulatory regions especially within intergenic sequences, linked to higher leptin gene expression in adult HF offspring in a depot-specific manner.

  20. Diversity Issues in the Army as Perceived by Army Students at the United States Army War College

    National Research Council Canada - National Science Library

    Webster, Cecil

    1997-01-01

    ..., welfare, and other related programs. In recognizing this diversity, this paper identifies some diversity issues within the Army, analyzes the perception of those diversity issues by the resident Army students in the USAWC Class of 1997...

  1. Comparative analysis of field ration for military personnel of the ukrainian army and armies of other countries worldwide

    OpenAIRE

    M. Mardar; M. Hkrupalo; M. Stateva

    2017-01-01

    For the purpose of improvement of the Ukrainian nutritional standards this Article provides comparative analysis of field rations of different countries worldwide to make a proposal on improvement of food-stuff assortment in food ration for military personnel in the Armed Forces of Ukraine, Army of USA, the British Army, Army of Germany, Army of Italy, Army of Canada, Army of France, Army of Belarus, Army of Armenia. In accordance with the comparative analysis it was established that ration c...

  2. Depot-medication compliance for patients with psychotic disorders: the importance of illness insight and treatment motivation.

    Science.gov (United States)

    Noordraven, Ernst L; Wierdsma, André I; Blanken, Peter; Bloemendaal, Anthony Ft; Mulder, Cornelis L

    2016-01-01

    Noncompliance is a major problem for patients with a psychotic disorder. Two important risk factors for noncompliance that have a severe negative impact on treatment outcomes are impaired illness insight and lack of motivation. Our cross-sectional study explored how they are related to each other and their compliance with depot medication. Interviews were conducted in 169 outpatients with a psychotic disorder taking depot medication. Four patient groups were defined based on low or high illness insight and on low or high motivation. The associations between depot-medication compliance, motivation, and insight were illustrated using generalized linear models. Generalized linear model showed a significant interaction effect between motivation and insight. Patients with poor insight and high motivation for treatment were more compliant (94%) (95% confidence interval [CI]: 1.821, 3.489) with their depot medication than patients with poor insight and low motivation (61%) (95% CI: 0.288, 0.615). Patients with both insight and high motivation for treatment were less compliant (73%) (95% CI: 0.719, 1.315) than those with poor insight and high motivation. Motivation for treatment was more strongly associated with depot-medication compliance than with illness insight. Being motivated to take medication, whether to get better or for other reasons, may be a more important factor than having illness insight in terms of improving depot-medication compliance. Possible implications for clinical practice are discussed.

  3. Differential sympathetic outflow to adipose depots is required for visceral fat loss in response to calorie restriction.

    Science.gov (United States)

    Sipe, L M; Yang, C; Ephrem, J; Garren, E; Hirsh, J; Deppmann, C D

    2017-04-10

    The sympathetic nervous system (SNS) regulates energy homeostasis in part by governing fatty acid liberation from adipose tissue. We first examined whether SNS activity toward discrete adipose depots changes in response to a weight loss diet in mice. We found that SNS activity toward each adipose depot is unique in timing, pattern of activation, and habituation with the most dramatic contrast between visceral and subcutaneous adipose depots. Sympathetic drive toward visceral epididymal adipose is more than doubled early in weight loss and then suppressed later in the diet when weight loss plateaued. Coincident with the decline in SNS activity toward visceral adipose is an increase in activity toward subcutaneous depots indicating a switch in lipolytic sources. In response to calorie restriction, SNS activity toward retroperitoneal and brown adipose depots is unaffected. Finally, pharmacological blockage of sympathetic activity on adipose tissue using the β3-adrenergic receptor antagonist, SR59230a, suppressed loss of visceral adipose mass in response to diet. These findings indicate that SNS activity toward discrete adipose depots is dynamic and potentially hierarchical. This pattern of sympathetic activation is required for energy liberation and loss of adipose tissue in response to calorie-restricted diet.

  4. Understanding of empty container movement: A study on a bottleneck at an off-dock depot

    Science.gov (United States)

    Zain, Rosmaizura Mohd; Rahman, Mohd Nizam Ab; Nopiah, Zulkifli Mohd; Saibani, Nizaroyani

    2014-09-01

    Port not only function as connections between marine and land transportation but also as core business areas. In a port terminal, available space is limited, but the influx of container is growing. The off-dock depot is one of the key supply chain players that hold empty containers in the inventory. Therefore, this paper aims to identify the main factors of bottlenecks or congestion that hinder the rapid movement of empty containers from the off-dock depot to the customers. Thirty interviews were conducted with individuals who are key players in the container supply chain. The data were analyzed using Atlas.ti software and the analytic hierarchy process to rank the priority factors of bottlenecks. Findings show that several pertinent factors act as barriers to the key players in the container movement in the day-to-day operations. In future studies, strategies to overcome fragmentation in the container supply chain and logistics must be determined.

  5. Optimizing the Shunting Schedule of Electric Multiple Units Depot Using an Enhanced Particle Swarm Optimization Algorithm

    Directory of Open Access Journals (Sweden)

    Jiaxi Wang

    2016-01-01

    Full Text Available The shunting schedule of electric multiple units depot (SSED is one of the essential plans for high-speed train maintenance activities. This paper presents a 0-1 programming model to address the problem of determining an optimal SSED through automatic computing. The objective of the model is to minimize the number of shunting movements and the constraints include track occupation conflicts, shunting routes conflicts, time durations of maintenance processes, and shunting running time. An enhanced particle swarm optimization (EPSO algorithm is proposed to solve the optimization problem. Finally, an empirical study from Shanghai South EMU Depot is carried out to illustrate the model and EPSO algorithm. The optimization results indicate that the proposed method is valid for the SSED problem and that the EPSO algorithm outperforms the traditional PSO algorithm on the aspect of optimality.

  6. On the multiple depots vehicle routing problem with heterogeneous fleet capacity and velocity

    Science.gov (United States)

    Hanum, F.; Hartono, A. P.; Bakhtiar, T.

    2018-03-01

    This current manuscript concerns with the optimization problem arising in a route determination of products distribution. The problem is formulated in the form of multiple depots and time windowed vehicle routing problem with heterogeneous capacity and velocity of fleet. Model includes a number of constraints such as route continuity, multiple depots availability and serving time in addition to generic constraints. In dealing with the unique feature of heterogeneous velocity, we generate a number of velocity profiles along the road segments, which then converted into traveling-time tables. An illustrative example of rice distribution among villages by bureau of logistics is provided. Exact approach is utilized to determine the optimal solution in term of vehicle routes and starting time of service.

  7. Give us back our field army! The Dutch army leadership and the operational planning during the interwar years

    NARCIS (Netherlands)

    Amersfoort, H.; Amersfoort, H.; Klinkert, W.

    2011-01-01

    The 1922 Army Reform Bill reduced the Dutch army to a militia. During the period between the two World Wars Dutch army leadership sought to rebuild an army that in several repects (organization, armement, doctrine) could be compared to the armies of great powers like France and Germany. The army

  8. Internal Controls over Army Selective Reenlistment Bonuses

    National Research Council Canada - National Science Library

    Granetto, Paul J; Marsh, Patricia; Neville, Douglas P; Powell, Joseph A; Penn, Lusk; Ward, Brett; Quimby, Donovan; Vega, Lisa; James, Jason; Matthews, Henry

    2008-01-01

    ...) is the Army's computerized retention system for enlisted personnel. It contains all the reenlistment data required to document the retention of Army Service members, including tracking selective reenlistment bonuses (SRBs...

  9. Army Forces for Operations Other Than War

    National Research Council Canada - National Science Library

    Sortor, Ronald

    1997-01-01

    ... contingencies influence the readiness and availability of Army forces to deploy to an MRC? We examine OOTW missions performed by the Army since 1975 and plans for possible future operations in order to define force requirements for OOTW...

  10. Obesity associated disease risk: the role of inherent differences and location of adipose depots.

    Science.gov (United States)

    Hill, Jessica H; Solt, Claudia; Foster, Michelle T

    2018-03-16

    Obesity and associated metabolic co-morbidities are a worldwide public health problem. Negative health outcomes associated with obesity, however, do not arise from excessive adiposity alone. Rather, deleterious outcomes of adipose tissue accumulation are a result of how adipocytes are distributed to individual regions in the body. Due to our increased understanding of the dynamic relationship that exists between specific adipose depots and disease risk, an accurate characterization of total body adiposity as well as location is required to properly evaluate a population's disease risk. Specifically, distinctive tissue depots within the body include the lower body, upper body and abdominal (deep and superficial) subcutaneous regions, as well as visceral (mesenteric and omental) regions. Upper body and visceral adipose tissues are highly associated with metabolic dysfunction and chronic disease development, whereas lower body gluteofemoral subcutaneous adipose tissue imparts protection against diet-induced metabolic derangement. Each adipose depot functions distinctly as an endocrine organ hence it has a different level of impact on health outcomes. Effluent from adipose tissue can modulate the functions of other tissues, whilst receiving differential communication from the rest of the body via central nervous system innervation, metabolites and other signaling molecules. More so, adipose depots contain a diverse reservoir of tissue-resident immune cells that play an integral part in both maintaining tissue homeostasis, as well as propagating metabolically-induced inflammation. Overall, the conceptualization of obesity and associated risks needs updating to reflect the complexities of obesity. We review adipose tissue characteristics that are linked to deleterious or beneficial adipose tissue distributions.

  11. HALF-DOSE DEPOT TRIPTORELIN COMPARABLE TO REDUCED DAILY BUSERELIN: A RANDOMIZED CLINICAL TRIAL

    Directory of Open Access Journals (Sweden)

    L. Safdarian

    2007-09-01

    Full Text Available Pituitary suppression by depot GnRH agonist may be excessive for ovarian stimulation. This study compares the efficacy of a single half-dose depot triptorelin and reduced-dose daily buserelin in a long protocol ICSI/ET. METHODS: A total of 182 patients were randomized into two groups using sealed envelopes. Pituitary desensitization was obtained in group 1 (91 patients with half-dose (1.87 mg depot triptorelin in the mid-luteal phase of their menstrual cycle, and in group 2 (91 patients with standard daily dose (0.5 mg buserelin, which was then reduced to 0.25 mg at the start of human menopausal gonadotropin (HMG stimulation. RESULTS: No significant differences were found among those who received HCG in terms of clinical pregnancy rate (34.4% in both groups, implantation rate (14.8% in group 1 versus 11.1% in group 2, fertilization rate (93.3 versus 95.6%, poor response rate (11.1 versus 6.7%, and miscarriage rate (11.1 versus 7.8%. No significant differences were seen in number of HMG ampoules used, follicles at HCG administration, and oocytes retrieved. The number of days of stimulation was significantly reduced in group 2 (11.2 +/- 1.8 in group 1 versus 10.6 +/- 1.9, p = 0.030. CONCLUSION: A half-dose of depot triptorelin can be successfully used in ovarian stimulation instead of reduced-dose daily buserelin, with more patient comfort and reduced stress and cost of injections.

  12. Study of Using Excess Stock to Reduce Naval Aviation Depot-Level Repairable Piece Part Backorders

    Science.gov (United States)

    2016-12-01

    large retail store with a small shopping list of only automotive parts. The volume of automotive parts available on the shelf is only a fraction of...the overall store inventory, and the specific nature of the shopping list renders the non- automotive inventory moot. The pool of candidate matches is...DEPOT-LEVEL REPAIRABLE PIECE PART BACKORDERS December 2016 By: Jennifer L. Custard Quentin E. Lease Jan D. Schotman Advisors: Geraldo

  13. Cortisol response in healthy and diseased dogs after stimulation with a depot formulation of synthetic ACTH

    OpenAIRE

    Sieber-Ruckstuhl, N S; Burkhardt, W A; Hofer-Inteeworn, N; Riond, B; Rast, I T; Hofmann-Lehmann, R; Reusch, C E; Boretti, F S

    2015-01-01

    BACKGROUND The ACTH stimulation test is used to evaluate the adrenocortical reserve. Recently, the availability of the synthetic ACTH formulation was limited, causing major problems in clinical practice. OBJECTIVES The objective of this study was to evaluate poststimulation peak cortisol concentrations and the duration of the stimulatory effect of a depot ACTH preparation in dogs. ANIMALS Twenty-two healthy dogs, 10 dogs with suspected hypoadrenocorticism (HA) and 15 dogs with suspected ...

  14. Control of Adipocyte Differentiation in Different Fat Depots; Implications for Pathophysiology or Therapy

    Directory of Open Access Journals (Sweden)

    Xiuquan eMa

    2015-01-01

    Full Text Available Adipocyte differentiation and its impact on restriction or expansion of particular adipose tissue depots has physiological and pathophysiological significance in view of the different functions of these depots. Brown or beige fat [BAT] expansion can enhance thermogenesis, lipid oxidation, insulin sensitivity and glucose tolerance; conversely expanded visceral fat [VAT] is associated with insulin resistance, low grade inflammation, dyslipidaemia and cardiometabolic risk. The largest depot, subcutaneous white fat [WAT], has important beneficial characteristics including storage of lipid out of harms way and secretion of adipokines, especially leptin and adiponectin, with positive metabolic effects including lipid oxidation, energy utilisation, enhanced insulin action and an anti-inflammatory role. The absence of these functions in lipodystrophies leads to major metabolic disturbances. An ability to expand WAT adipocyte differentiation would seem an important defence mechanism against the detrimental effects of energy excess and limit harmful accumulation of lipid in ectopic sites, such as liver and muscle.Adipocyte differentiation involves a transcriptional cascade with PPARg being most important in WAT but less so in VAT, with increased angiogenesis also critical. The transcription factor, Islet1, is fairly specific to VAT and in vitro inhibits adipocyte differentiation. The physiological importance of Islet1 requires further study. Basic control of differentiation is similar in BAT but important differences include the effect of PGC-1a on mitochondrial biosynthesis and upregulation of UCP1; also PRDM16 plays a pivotal role in expression of the BAT phenotype.Modulation of the capacity or function of these different adipose tissue depots, by altering adipocyte differentiation or other means, holds promise for interventions that can be helpful in human disease, particularly cardiometabolic disorders associated with the world wide explosion of

  15. Moisture mapping of aeronautical museum depot and galleries by IR thermography

    OpenAIRE

    Ristić, Slavica; Polić-Radovanović, Suzana; Jegdić, Bore; Ristić, Radovan; Radojković, Bojana

    2012-01-01

    The paper presents the results of moisture detection in the depot and galleries of the Aeronautical Museum in Belgrade. The moisture and changeable temperature conditions are the main causes for corrosion in historical buildings and museum artifacts. The main purpose of the tests was to determine these conditions in the museum where very important metal artifacts are exhibited and deposed, including the only surviving example of the Fiat G50 aircraft, by applying passive IR thermography. The ...

  16. The relationship between fat depot-specific preadipocyte differentiation and metabolic syndrome in obese women

    Directory of Open Access Journals (Sweden)

    N V Mazurina

    2013-03-01

    Full Text Available Реферат по материалам статьи The relationship between fat depot-specific preadipocyte differentiation and metabolic syndrome in obese women. Park HТ, Lee ES, Cheon EP, Lee DR, Yang K-S, Kim YT, Hur JY, Kim SH, Lee KW, Kim T. Clinical Endocrinology 2012; 76, 59-66.

  17. AUTOMATED DETECTION OF OIL DEPOTS FROM HIGH RESOLUTION IMAGES: A NEW PERSPECTIVE

    Directory of Open Access Journals (Sweden)

    A. O. Ok

    2015-03-01

    Full Text Available This paper presents an original approach to identify oil depots from single high resolution aerial/satellite images in an automated manner. The new approach considers the symmetric nature of circular oil depots, and it computes the radial symmetry in a unique way. An automated thresholding method to focus on circular regions and a new measure to verify circles are proposed. Experiments are performed on six GeoEye-1 test images. Besides, we perform tests on 16 Google Earth images of an industrial test site acquired in a time series manner (between the years 1995 and 2012. The results reveal that our approach is capable of detecting circle objects in very different/difficult images. We computed an overall performance of 95.8% for the GeoEye-1 dataset. The time series investigation reveals that our approach is robust enough to locate oil depots in industrial environments under varying illumination and environmental conditions. The overall performance is computed as 89.4% for the Google Earth dataset, and this result secures the success of our approach compared to a state-of-the-art approach.

  18. 32 CFR 651.5 - Army policies.

    Science.gov (United States)

    2010-07-01

    ... defense. The Army is expected to manage those aspects of the environment affected by Army activities... important environmental resources, and the capacity of Army decisions to influence those effects in a... project planning and decision-making. Efficiency will be promoted through the following: (1) Awareness and...

  19. 76 FR 12087 - Army Educational Advisory Committee

    Science.gov (United States)

    2011-03-04

    ...: U.S. Army War College Subcommittee of the Army Education Advisory Committee. Dates of Meeting: March 24, 2011. Place of Meeting: U.S. Army War College, 122 Forbes Avenue, Carlisle, PA, Command... faculty; table and examine online College issues; assess resident and distance education programs, self...

  20. 75 FR 7255 - Army Educational Advisory Committee

    Science.gov (United States)

    2010-02-18

    ... Committee: U.S. Army War College Subcommittee of the Army Education Advisory Committee. Date of Meeting: March 11, 2010. Place of Meeting: U.S. Army War College, 122 Forbes Avenue, Carlisle, PA, Command...; table and examine online College issues; assess resident and distance education programs, self- study...

  1. Employment-based reinforcement of adherence to depot naltrexone in unemployed opioid-dependent adults: a randomized controlled trial.

    Science.gov (United States)

    Everly, Jeffrey J; DeFulio, Anthony; Koffarnus, Mikhail N; Leoutsakos, Jeannie-Marie S; Donlin, Wendy D; Aklin, Will M; Umbricht, Annie; Fingerhood, Michael; Bigelow, George E; Silverman, Kenneth

    2011-07-01

    Naltrexone can be used to treat opioid dependence, but patients refuse to take it. Extended-release depot formulations may improve adherence, but long-term adherence rates to depot naltrexone are not known. This study determined long-term rates of adherence to depot naltrexone and whether employment-based reinforcement can improve adherence. Participants who were inducted onto oral naltrexone were assigned randomly to contingency (n = 18) or prescription (n = 17) groups. Participants were offered six depot naltrexone injections and invited to work at the therapeutic workplace on week days for 26 weeks, where they earned stipends for participating in job skills training. Contingency participants were required to accept naltrexone injections to maintain workplace access and to maintain maximum pay. Prescription participants could work independently of whether they accepted injections. The therapeutic workplace, a model employment-based intervention for drug addiction and unemployment. Opioid-dependent unemployed adults. Depot naltrexone injections accepted and opiate-negative urine samples. Contingency participants accepted significantly more naltrexone injections than prescription participants (81% versus 42%), and were more likely to accept all injections (66% versus 35%). At monthly assessments (with missing urine samples imputed as positive), the groups provided similar percentages of samples negative for opiates (74% versus 62%) and for cocaine (56% versus 54%). Opiate-positive samples were more likely when samples were also positive for cocaine. Employment-based reinforcement can maintain adherence to depot naltrexone. Future research should determine whether persistent cocaine use compromises naltrexone's effect on opiate use. Workplaces may be useful for promoting sustained adherence to depot naltrexone. © 2011 The Authors, Addiction © 2011 Society for the Study of Addiction.

  2. Characterization of stromal vascular fraction and adipose stem cells from subcutaneous, preperitoneal and visceral morbidly obese human adipose tissue depots.

    Science.gov (United States)

    Silva, Karina Ribeiro; Côrtes, Isis; Liechocki, Sally; Carneiro, João Regis Ivar; Souza, Antônio Augusto Peixoto; Borojevic, Radovan; Maya-Monteiro, Clarissa Menezes; Baptista, Leandra Santos

    2017-01-01

    The pathological condition of obesity is accompanied by a dysfunctional adipose tissue. We postulate that subcutaneous, preperitoneal and visceral obese abdominal white adipose tissue depots could have stromal vascular fractions (SVF) with distinct composition and adipose stem cells (ASC) that would differentially account for the pathogenesis of obesity. In order to evaluate the distribution of SVF subpopulations, samples of subcutaneous, preperitoneal and visceral adipose tissues from morbidly obese women (n = 12, BMI: 46.2±5.1 kg/m2) were collected during bariatric surgery, enzymatically digested and analyzed by flow cytometry (n = 12). ASC from all depots were evaluated for morphology, surface expression, ability to accumulate lipid after induction and cytokine secretion (n = 3). A high content of preadipocytes was found in the SVF of subcutaneous depot (p = 0.0178). ASC from the three depots had similar fibroblastoid morphology with a homogeneous expression of CD34, CD146, CD105, CD73 and CD90. ASC from the visceral depot secreted the highest levels of IL-6, MCP-1 and G-CSF (p = 0.0278). Interestingly, preperitoneal ASC under lipid accumulation stimulus showed the lowest levels of all the secreted cytokines, except for adiponectin that was enhanced (p = 0.0278). ASC from preperitoneal adipose tissue revealed the less pro-inflammatory properties, although it is an internal adipose depot. Conversely, ASC from visceral adipose tissue are the most pro-inflammatory. Therefore, ASC from subcutaneous, visceral and preperitoneal adipose depots could differentially contribute to the chronic inflammatory scenario of obesity.

  3. The Army word recognition system

    Science.gov (United States)

    Hadden, David R.; Haratz, David

    1977-01-01

    The application of speech recognition technology in the Army command and control area is presented. The problems associated with this program are described as well as as its relevance in terms of the man/machine interactions, voice inflexions, and the amount of training needed to interact with and utilize the automated system.

  4. The Army and Team Learning

    Science.gov (United States)

    2008-05-01

    synthesis of the knowledge, skills and experiences gained through the synergy of the three domains of the Army Leader...Inventory Article by MAJ 1 1 CPT Letter Response to Grant Log Art. 0 "Logistocrat" Article Asymetric Sustainment Article 1 1 Response Letter to Nov 02 Art

  5. Army Transformation to Expeditionary Formations

    National Research Council Canada - National Science Library

    Bryson, Jeff

    2008-01-01

    This thesis explores the path of transformation in the U.S. Army from its inception in the late 1990s by then Chief of Staff GEN Eric Shinseki to the Interim Brigade Combat Team and through Operations Enduring and Iraqi Freedom...

  6. Drug Abuse in the Army.

    Science.gov (United States)

    The essay discusses the growth of drug abuse in the Army, actions that have been taken to control the problem, and planned or proposed actions to...and supervisory personnel of the Drug Abuse Control Division in the Office of the Deputy Chief of Staff for Personnel, Headquarters, Department of

  7. Inverting the Army Intelligence Pyramid

    Science.gov (United States)

    2011-05-19

    Counterinsurgency, Company Intelligence Support Team, COIST, HUMINT, SIGINT, MASINT, OSINT 16. SECURITY CLASSIFICATION OF: (U) 17. LIMITATION OF...intelligence ( OSINT ), signals intelligence (SIGINT), and technical intelligence (TECHINT).14 11...new ways to support the needs of commanders, especially company-level commanders. The slow-moving and complex framework of the Army acquisition system

  8. 2012 Center for Army Leadership Annual Survey of Army Leadership (CASAL): Army Civilian Leaders

    Science.gov (United States)

    2013-05-23

    PLEASE DO NOT RETURN YOUR FORM TO THE ABOVE ADDRESS. 1. REPORT DATE (DD-MM-YYYY) 23-05-2013 2. REPORT TYPE Technical Report 3. DATES COVERED...VDAS_ArmyPostureStatement/2011/information_p apers /PostedDocument.asp?id=210 United States Office of Personnel Management (2012). Federal employee viewpoint survey

  9. 77 FR 9633 - Army National Cemeteries Advisory Commission (ANCAC)

    Science.gov (United States)

    2012-02-17

    ... DEPARTMENT OF DEFENSE Department of the Army Army National Cemeteries Advisory Commission (ANCAC) AGENCY: Department of the Army, DoD. ACTION: Notice of open committee meeting. SUMMARY: Pursuant to the...), the Department of the Army announces the following committee meeting: Name of Committee: Army National...

  10. Eradicating hepatitis C virus ameliorates insulin resistance without change in adipose depots.

    Science.gov (United States)

    Milner, K-L; Jenkins, A B; Trenell, M; Tid-Ang, J; Samocha-Bonet, D; Weltman, M; Xu, A; George, J; Chisholm, D J

    2014-05-01

    Chronic hepatitis C (CHC) is associated with lipid-related changes and insulin resistance; the latter predicts response to antiviral therapy, liver disease progression and the risk of diabetes. We sought to determine whether insulin sensitivity improves following CHC viral eradication after antiviral therapy and whether this is accompanied by changes in fat depots or adipokine levels. We compared 8 normoglycaemic men with CHC (genotype 1 or 3) before and at least 6 months post viral eradication and 15 hepatitis C antibody negative controls using an intravenous glucose tolerance test and two-step hyperinsulinaemic-euglycaemic clamp with [6,6-(2) H2 ] glucose to assess peripheral and hepatic insulin sensitivity. Magnetic resonance imaging and spectroscopy quantified abdominal fat compartments, liver and intramyocellular lipid. Peripheral insulin sensitivity improved (glucose infusion rate during high-dose insulin increased from 10.1 ± 1.6 to 12 ± 2.1 mg/kg/min/, P = 0.025), with no change in hepatic insulin response following successful viral eradication, without any accompanying change in muscle, liver or abdominal fat depots. There was corresponding improvement in incremental glycaemic response to intravenous glucose (pretreatment: 62.1 ± 8.3 vs post-treatment: 56.1 ± 8.5 mm, P = 0.008). Insulin sensitivity after viral clearance was comparable to matched controls without CHC. Post therapy, liver enzyme levels decreased but, interestingly, levels of glucagon, fatty acid-binding protein and lipocalin-2 remained elevated. Eradication of the hepatitis C virus improves insulin sensitivity without alteration in fat depots, adipokine or glucagon levels, consistent with a direct link of the virus with insulin resistance. © 2013 John Wiley & Sons Ltd.

  11. Cortisol Response in Healthy and Diseased Dogs after Stimulation with a Depot Formulation of Synthetic ACTH.

    Science.gov (United States)

    Sieber-Ruckstuhl, N S; Burkhardt, W A; Hofer-Inteeworn, N; Riond, B; Rast, I T; Hofmann-Lehmann, R; Reusch, C E; Boretti, F S

    2015-01-01

    The ACTH stimulation test is used to evaluate the adrenocortical reserve. Recently, the availability of the synthetic ACTH formulation was limited, causing major problems in clinical practice. The objective of this study was to evaluate poststimulation peak cortisol concentrations and the duration of the stimulatory effect of a depot ACTH preparation in dogs. Twenty-two healthy dogs, 10 dogs with suspected hypoadrenocorticism (HA) and 15 dogs with suspected hyperadrenocorticism (HC). Prospective study. An ACTH stimulation test using a synthetic depot tetracosactide, administered intramuscularly (5 μg/kg or at least 0.1 mL) was performed. Blood samples for determination of cortisol were taken immediately before and 1, 2, 3, 4, 6, and 24 hours after stimulation. Peak cortisol concentrations were reached after 2-4 hours in all dogs. Cortisol concentrations 1 hour after stimulation were >9 μg/dL in all healthy dogs and >5 μg/dL in all dogs in which HA was excluded. None of the dogs with HA showed a cortisol-increase above the detection-limit of the assay. After 6 hours, cortisol concentrations had decreased in the healthy and HC group and were back to baseline after 24 hours. The depot formulation can be used in place of the short-acting ACTH to evaluate the adrenocortical reserve. Blood for peak cortisol concentrations should be drawn 3 hours after stimulation in cases in which HC is suspected; in HA-suspected cases, blood sampling can take place after 1 hour. As the stimulatory effect is gone after 24 hours, interference with other hormonal tests is unlikely after that time. Copyright © 2015 The Authors. Journal of Veterinary Internal Medicine published by Wiley Periodicals, Inc. on behalf of the American College of Veterinary Internal Medicine.

  12. Direct evidence of brown adipocytes in different fat depots in children.

    Directory of Open Access Journals (Sweden)

    Denise Rockstroh

    Full Text Available Recent studies suggested the persistence of brown adipocytes in adult humans, as opposed to being exclusively present in infancy. In this study, we investigated the presence of brown-like adipocytes in adipose tissue (AT samples of children and adolescents aged 0 to 18 years and evaluated the association with age, location, and obesity. For this, we analysed AT samples from 131 children and 23 adults by histological, immunohistochemical and expression analyses. We detected brown-like and UCP1 positive adipocytes in 10.3% of 87 lean children (aged 0.3 to 10.7 years and in one overweight infant, whereas we did not find brown adipocytes in obese children or adults. In our samples, the brown-like adipocytes were interspersed within white AT of perirenal, visceral and also subcutaneous depots. Samples with brown-like adipocytes showed an increased expression of UCP1 (>200fold, PRDM16 (2.8fold, PGC1α and CIDEA while other brown/beige selective markers, such as PAT2, P2RX5, ZIC1, LHX8, TMEM26, HOXC9 and TBX1 were not significantly different between UCP1 positive and negative samples. We identified a positive correlation between UCP1 and PRDM16 within UCP1 positive samples, but not with any other brown/beige marker. In addition, we observed significantly increased PRDM16 and PAT2 expression in subcutaneous and visceral AT samples with high UCP1 expression in adults. Our data indicate that brown-like adipocytes are present well beyond infancy in subcutaneous depots of non-obese children. The presence was not restricted to typical perirenal locations, but they were also interspersed within WAT of visceral and subcutaneous depots.

  13. PENGARUH PENGOLAHAN AIR DI DEPOT AIR MINUM ISI ULANG DALAM MENORMALKAN DERAJAT KEASAMAN (pH)

    OpenAIRE

    Athena Athena; Sukar Sukar; Hendro M.; D. Anwar M.

    2012-01-01

    In 2003, it had been performed a study to assess drinking water quality produced by drinking water refill depot (AMIU) in Jabotabek. The objective of the study is to evaluate the effect of drinking water treatment process of the AMIU in normalizing of acidity level, especially for pH parameter. Water pH level is necessary to assess in line with the determination  of its use, for household use as drinking water or for the AMIU for raw material. According to laboratory analysis result, it can b...

  14. Pengaruh Pengolahan Air Di Depot Air Minum Isi Ulang Dalam Menormalkan Derajat Keasaman (Ph)

    OpenAIRE

    Athena, Athena; Sukar, Sukar; M., Hendro; M., D. Anwar

    2005-01-01

    In 2003, it had been performed a study to assess drinking water quality produced by drinking water refill depot (AMIU) in Jabotabek. The objective of the study is to evaluate the effect of drinking water treatment process of the AMIU in normalizing of acidity level, especially for pH parameter. Water pH level is necessary to assess in line with the determination of its use, for household use as drinking water or for the AMIU for raw material. According to laboratory analysis result, it can b...

  15. Using Genetic Algorithm For Winter Maintenance Operations: Multi Depot K-Chinese Postman Problem

    Directory of Open Access Journals (Sweden)

    İbrahim Zeki Akyurt

    2015-02-01

    Full Text Available In this study, the assignment and routing problem of one of Istanbul’s winter maintenance activities, salt pouring, was scrutinized. The starting point of the study considers the high cost of winter maintenance work, a shrinking assigned budget, high numbers of vehicles and streets to service that the increase in difficulty to solve the problem due to their high numbers. In this respect, the problem was modeled as multi depot k-Chinese postman problem, a type of arc routing problem. This mathematical model was solved by genetic algorithm. For comparison, the current solution, Clarke and Wright Algorithm and Sweep Algorithm were used.

  16. Anaphylaxis Triggered by Benzyl Benzoate in a Preparation of Depot Testosterone Undecanoate

    Directory of Open Access Journals (Sweden)

    Gregory S. Y. Ong

    2012-01-01

    Full Text Available We report the first case of an anaphylactic reaction to Reandron 1000 (depot testosterone undecanoate with a castor oil and benzyl benzoate vehicle. While considered to have a favourable safety profile, serious complications such as oil embolism and anaphylaxis can occur. In our patient, skin testing identified benzyl benzoate to be the trigger, with no reaction to castor oil or testosterone undecanoate components. As benzyl benzoate exists in multiple pharmaceuticals, foods, and cosmetics, individual components of pharmaceuticals should be tested when investigating drug allergies. Doctors should be alert to the potential for serious reactions to any of the components of Reandron 1000.

  17. KANDUNGAN Pb, Cd, Hg DALAM AIR MINUM DARI DEPOT AIR MINUM ISI ULANG DI JAKARTA, TANGERANG, DAN BEKASI

    Directory of Open Access Journals (Sweden)

    Athena Athena

    2012-11-01

    Full Text Available A study on chemical quality of drinking water from reffil depots was done in Jakarta, Tangerang, and Bekasi in 2003 to determine the contents of heavy metals such as lead (Pb, cadmium, (Cd, and Mercury (Hg. A total of 38 refill depots was selected as samples. Data were collected by water sampling collection and water analysis, and interview with operators and association personal using questionairs. Water samples were analyzed using Atomic Absorption Spectrophotometer (AAS to examine the contents of their heavy metals based on raw water and drinking water standards. The results showed that the treatment processed were filtration and disinfection. However, the contents of heavy metals in the two types of water samples still complied with the standards stated in Health Ministerial Decree no 906 in the year 2002.   Keywords: heavy metals, drinking water, drinking water refill depots

  18. Comparison of human adipose-derived stem cells isolated from subcutaneous, omental, and intrathoracic adipose tissue depots for regenerative applications.

    Science.gov (United States)

    Russo, Valerio; Yu, Claire; Belliveau, Paul; Hamilton, Andrew; Flynn, Lauren E

    2014-02-01

    Adipose tissue is an abundant source of multipotent progenitor cells that have shown promise in regenerative medicine. In humans, fat is primarily distributed in the subcutaneous and visceral depots, which have varying biochemical and functional properties. In most studies to date, subcutaneous adipose tissue has been investigated as the adipose-derived stem cell (ASC) source. In this study, we sought to develop a broader understanding of the influence of specific adipose tissue depots on the isolated ASC populations through a systematic comparison of donor-matched abdominal subcutaneous fat and omentum, and donor-matched pericardial adipose tissue and thymic remnant samples. We found depot-dependent and donor-dependent variability in the yield, viability, immunophenotype, clonogenic potential, doubling time, and adipogenic and osteogenic differentiation capacities of the ASC populations. More specifically, ASCs isolated from both intrathoracic depots had a longer average doubling time and a significantly higher proportion of CD34(+) cells at passage 2, as compared with cells isolated from subcutaneous fat or the omentum. Furthermore, ASCs from subcutaneous and pericardial adipose tissue demonstrated enhanced adipogenic differentiation capacity, whereas ASCs isolated from the omentum displayed the highest levels of osteogenic markers in culture. Through cell culture analysis under hypoxic (5% O(2)) conditions, oxygen tension was shown to be a key mediator of colony-forming unit-fibroblast number and osteogenesis for all depots. Overall, our results suggest that depot selection is an important factor to consider when applying ASCs in tissue-specific cell-based regenerative therapies, and also highlight pericardial adipose tissue as a potential new ASC source.

  19. Army Contract Writing System (ACWS)

    Science.gov (United States)

    2016-03-01

    2016 Major Automated Information System Annual Report Army Contract Writing System (ACWS) Defense Acquisition Management Information Retrieval...Military Construction MS - Milestone N/A - Not Applicable O&S - Operating and Support OSD - Office of the Secretary of Defense PB - President’s...Budget RDT&E - Research, Development, Test, and Evaluation SAE - Service Acquisition Executive TBD - To Be Determined TY - Then Year U.S.C- United

  20. The Marketability of Army Officers

    Science.gov (United States)

    1992-04-14

    capital ( Nussbaum , 1988).I I I I 1 19 I Governmental measures at the state level which foster job training include the California Employment Training I...Plight. Business Month, 133 (1) : 50-51. Nussbaum , B. 1988. Needed: Human Capital. Business Week, 3070: 100-103. Novack, J. 1991. Back to civy street...The second son of Howell J. and Martha Malham, he graduated from Memorial High School, Houston, I Texas, in May 1976 and entered the United States Army

  1. 2011 Army Strategic Planning Guidance

    Science.gov (United States)

    2011-03-25

    TESI ) of 22,000 Soldiers, the Army’s total force by the end of the mid-term period is programmed to be 520K (AC). We will achieve a more...dwell ratios, extending TESI authority to adequately man deploying units and sustain the All-Volunteer Force, right-sizing the generating force, and... TESI Temporary End-Strength Increase WMD Weapons of Mass Destruction 2011 ARMY STRATEGIC PLANNING GUIDANCE Page 19 2011

  2. Acquisition: Army Claims Service Military Interdepartmental Purchase Requests

    National Research Council Canada - National Science Library

    2002-01-01

    .... The Army Claims Service supports the Army and the Judge Advocate General Corps by managing the Army claims system, which includes processing tort and personnel claims, and recovering funds owed...

  3. Issues and Insights from the Army Technology Seminar Game

    National Research Council Canada - National Science Library

    Darilek, Richard

    2001-01-01

    ...). The AAN goals were to link Army XXI to a long-term vision of the Army extending well into the 21st century and to ensure that this vision informed evolving Army research and development requirements...

  4. Controls Over Army Real Property Financial Reporting

    Science.gov (United States)

    2008-03-28

    Controls Over Army Real Property Financial Reporting Report No. D-2008-072 March 28, 2008 Report Documentation Page Form...COVERED 00-00-2008 to 00-00-2008 4. TITLE AND SUBTITLE Controls Over Army Real Property Financial Reporting 5a. CONTRACT NUMBER 5b. GRANT NUMBER...DIRECTOR, DEFENSE FINANCE AND ACCOUNTING SERVICE SUBJECT: Report on Controls Over Army Real Property Financial Reporting ( Report No. D-2008-072

  5. Design of Hybrid Gels Based on Gellan-Cholesterol Derivative and P90G Liposomes for Drug Depot Applications

    Directory of Open Access Journals (Sweden)

    Nicole Zoratto

    2017-05-01

    Full Text Available Gels are extensively studied in the drug delivery field because of their potential benefits in therapeutics. Depot gel systems fall in this area, and the interest in their development has been focused on long-lasting, biocompatible, and resorbable delivery devices. The present work describes a new class of hybrid gels that stem from the interaction between liposomes based on P90G phospholipid and the cholesterol derivative of the polysaccharide gellan. The mechanical properties of these gels and the delivery profiles of the anti-inflammatory model drug diclofenac embedded in such systems confirmed the suitability of these hybrid gels as a good candidate for drug depot applications.

  6. A constructive heuristic for time-dependent multi-depot vehicle routing problem with time-windows and heterogeneous fleet

    Directory of Open Access Journals (Sweden)

    Behrouz Afshar-Nadjafi

    2017-01-01

    Full Text Available In this paper, we consider the time-dependent multi-depot vehicle routing problem. The objective is to minimize the total heterogeneous fleet cost assuming that the travel time between locations depends on the departure time. Also, hard time window constraints for the customers and limitation on maximum number of the vehicles in depots must be satisfied. The problem is formulated as a mixed integer programming model. A constructive heuristic procedure is proposed for the problem. Also, the efficiency of the proposed algorithm is evaluated on 180 test problems. The obtained computational results indicate that the procedure is capable to obtain a satisfying solution.

  7. 2013 CENTER FOR ARMY LEADERSHIP ANNUAL SURVEY OF ARMY LEADERSHIP (CASAL): MAIN FINDINGS

    Science.gov (United States)

    2014-04-30

    Leadership Requirements Model and Leader Effectiveness Implicit leadership theory (Eden & Leviatan, 1975; Yukl, 2002) indicates followers’ perceptions...Department of the Army. Eden, D. & Leviatan, U. (1975). Implicit leadership theory as a determinant of the factor structure underlying supervisory...2013 CENTER FOR ARMY LEADERSHIP ANNUAL SURVEY OF ARMY LEADERSHIP (CASAL): MAIN FINDINGS TECHNICAL REPORT 2014-01 Ryan

  8. Addressing Deficiencies in Army Civilian Leader Development

    National Research Council Canada - National Science Library

    Keller, Jonathan S

    2008-01-01

    .... A well managed, comparable, and integrated Army leader training, education, and development framework, designed to create shared and combined developmental experiences, is essential for growing...

  9. Relationships between rodent white adipose fat pads and human white adipose fat depots

    Directory of Open Access Journals (Sweden)

    Daniella E. Chusyd

    2016-04-01

    Full Text Available The objective of this review was to compare and contrast the physiological and metabolic profiles of rodent white adipose fat pads with white adipose fat depots in humans. Human fat distribution and its metabolic consequences have received extensive attention, but much of what has been tested in translational research has relied heavily on rodents. Unfortunately, the validity of using rodent fat pads as a model of human adiposity has received less attention. There is a surprisingly lack of studies demonstrating an analogous relationship between rodent and human adiposity on obesity-related comorbidities. Therefore, we aimed to compare known similarities and disparities in terms of white adipose tissue development and distribution, sexual dimorphism, weight loss, adipokine secretion, and aging. While the literature supports the notion that many similarities exist between rodents and humans, notable differences emerge related to fat deposition and function of white adipose tissue. Thus, further research is warranted to more carefully define the strengths and limitations of rodent white adipose tissue as a model for humans, with a particular emphasis on comparable fat depots, such as mesenteric fat.

  10. SeqDepot: streamlined database of biological sequences and precomputed features.

    Science.gov (United States)

    Ulrich, Luke E; Zhulin, Igor B

    2014-01-15

    Assembling and/or producing integrated knowledge of sequence features continues to be an onerous and redundant task despite a large number of existing resources. We have developed SeqDepot-a novel database that focuses solely on two primary goals: (i) assimilating known primary sequences with predicted feature data and (ii) providing the most simple and straightforward means to procure and readily use this information. Access to >28.5 million sequences and 300 million features is provided through a well-documented and flexible RESTful interface that supports fetching specific data subsets, bulk queries, visualization and searching by MD5 digests or external database identifiers. We have also developed an HTML5/JavaScript web application exemplifying how to interact with SeqDepot and Perl/Python scripts for use with local processing pipelines. Freely available on the web at http://seqdepot.net/. RESTaccess via http://seqdepot.net/api/v1. Database files and scripts maybe downloaded from http://seqdepot.net/download.

  11. A two-stage approach to the depot shunting driver assignment problem with workload balance considerations.

    Science.gov (United States)

    Wang, Jiaxi; Gronalt, Manfred; Sun, Yan

    2017-01-01

    Due to its environmentally sustainable and energy-saving characteristics, railway transportation nowadays plays a fundamental role in delivering passengers and goods. Emerged in the area of transportation planning, the crew (workforce) sizing problem and the crew scheduling problem have been attached great importance by the railway industry and the scientific community. In this paper, we aim to solve the two problems by proposing a novel two-stage optimization approach in the context of the electric multiple units (EMU) depot shunting driver assignment problem. Given a predefined depot shunting schedule, the first stage of the approach focuses on determining an optimal size of shunting drivers. While the second stage is formulated as a bi-objective optimization model, in which we comprehensively consider the objectives of minimizing the total walking distance and maximizing the workload balance. Then we combine the normalized normal constraint method with a modified Pareto filter algorithm to obtain Pareto solutions for the bi-objective optimization problem. Furthermore, we conduct a series of numerical experiments to demonstrate the proposed approach. Based on the computational results, the regression analysis yield a driver size predictor and the sensitivity analysis give some interesting insights that are useful for decision makers.

  12. A Fuzzy Goal Programming for a Multi-Depot Distribution Problem

    Science.gov (United States)

    Nunkaew, Wuttinan; Phruksaphanrat, Busaba

    2010-10-01

    A fuzzy goal programming model for solving a Multi-Depot Distribution Problem (MDDP) is proposed in this research. This effective proposed model is applied for solving in the first step of Assignment First-Routing Second (AFRS) approach. Practically, a basic transportation model is firstly chosen to solve this kind of problem in the assignment step. After that the Vehicle Routing Problem (VRP) model is used to compute the delivery cost in the routing step. However, in the basic transportation model, only depot to customer relationship is concerned. In addition, the consideration of customer to customer relationship should also be considered since this relationship exists in the routing step. Both considerations of relationships are solved using Preemptive Fuzzy Goal Programming (P-FGP). The first fuzzy goal is set by a total transportation cost and the second fuzzy goal is set by a satisfactory level of the overall independence value. A case study is used for describing the effectiveness of the proposed model. Results from the proposed model are compared with the basic transportation model that has previously been used in this company. The proposed model can reduce the actual delivery cost in the routing step owing to the better result in the assignment step. Defining fuzzy goals by membership functions are more realistic than crisps. Furthermore, flexibility to adjust goals and an acceptable satisfactory level for decision maker can also be increased and the optimal solution can be obtained.

  13. The disposal of low and intermediate-level radioactive wastes: the Elstow Storage Depot

    International Nuclear Information System (INIS)

    1983-10-01

    This document explains the role of NIREX (Nuclear Industry Radioactive Waste Executive) in planning for the safe disposal of low and intermediate-level radioactive wastes and outlines the plans for the investigation and possible development of a new shallow repository at the CEGB's Elstow Storage Depot, Bedfordshire. The site is conveniently located and is situated on a suitable geologic formation, the Oxford Clay. The next step is for NIREX to undertake site investigations and assess in detail the site's suitability. On the basis of this assessment NIREX will either confirm its interest in the site or reject it as unsuitable. If the site proves to be adequate for the development of a shallow repository then NIREX will seek the necessary planning approvals and authorisations for such a development. The development would involve the construction of new buildings and a programme of trench excavation, waste positioning and trench closure. Existing tenants at the Depot will be accommodated as far as possible. The existing road and rail networks would be used for delivering the packaged wastes. In designing and operating any repository the safety of the public and workforce, both now and in the future, will be of paramount importance. (author)

  14. A two-stage approach to the depot shunting driver assignment problem with workload balance considerations.

    Directory of Open Access Journals (Sweden)

    Jiaxi Wang

    Full Text Available Due to its environmentally sustainable and energy-saving characteristics, railway transportation nowadays plays a fundamental role in delivering passengers and goods. Emerged in the area of transportation planning, the crew (workforce sizing problem and the crew scheduling problem have been attached great importance by the railway industry and the scientific community. In this paper, we aim to solve the two problems by proposing a novel two-stage optimization approach in the context of the electric multiple units (EMU depot shunting driver assignment problem. Given a predefined depot shunting schedule, the first stage of the approach focuses on determining an optimal size of shunting drivers. While the second stage is formulated as a bi-objective optimization model, in which we comprehensively consider the objectives of minimizing the total walking distance and maximizing the workload balance. Then we combine the normalized normal constraint method with a modified Pareto filter algorithm to obtain Pareto solutions for the bi-objective optimization problem. Furthermore, we conduct a series of numerical experiments to demonstrate the proposed approach. Based on the computational results, the regression analysis yield a driver size predictor and the sensitivity analysis give some interesting insights that are useful for decision makers.

  15. The multi-depot electric vehicle location routing problem with time windows

    Directory of Open Access Journals (Sweden)

    Juan Camilo Paz

    2018-01-01

    Full Text Available In this paper, the Multi-Depot Electric Vehicle Location Routing Problem with Time Windows (MDVLRP is addressed. This problem is an extension of the MDVLRP, where electric vehicles are used instead of internal combustion engine vehicles. The recent development of this model is explained by the advantages of this technology, such as the diminution of carbon dioxide emissions, and the support that they can provide to the design of the logistic and energy-support structure of electric vehicle fleets. There are many models that extend the classical VRP model to take electric vehicles into consideration, but the multi-depot case for location-routing models has not been worked out yet. Moreover, we consider the availability of two energy supply technologies: the “Plug-in” Conventional Charge technology, and Battery Swapping Stations; options in which the recharging time is a function of the amount of energy to charge and a fixed time, respectively. Three models are proposed: one for each of the technologies mentioned above, and another in which both options are taken in consideration. The models were solved for small scale instances using C++ and Cplex 12.5. The results show that the models can be used to design logistic and energy-support structures, and compare the performance of the different options of energy supply, as well as measure the impact of these decisions on the overall distance traveled or other optimization objectives that could be worked on in the future.

  16. Sexual Assault: Better Resource Management Needed to Improve Prevention and Response in the Army National Guard and Army Reserve

    Science.gov (United States)

    2017-02-01

    the commanding officer of an accused servicemember. 21Army Regulation 600-20 defines sexual harassment as a form of gender discrimination that...SEXUAL ASSAULT Better Resource Management Needed to Improve Prevention and Response in the Army National Guard and Army...Resource Management Needed to Improve Prevention and Response in the Army National Guard and Army Reserve What GAO Found The Army National Guard

  17. Suicide Attempts in the United States Army

    Science.gov (United States)

    Ursano, Robert J.; Kessler, Ronald C.; Stein, Murray B.; Naifeh, James A.; Aliaga, Pablo A.; Fullerton, Carol S.; Sampson, Nancy A.; Kao, Tzu-Cheg; Colpe, Lisa J.; Schoenbaum, Michael; Cox, Kenneth L.; Heeringa, Steven G.

    2015-01-01

    Importance The U.S. Army suicide attempt rate increased sharply during the wars in Afghanistan and Iraq. Comprehensive research on this important health outcome has been hampered by a lack of integration among Army administrative data systems. Objective To identify risk factors for Regular Army suicide attempts during the years 2004–2009 using data from the Army Study to Assess Risk and Resilience in Servicemembers (Army STARRS). Design, Setting, and Participants There were 9,791 medically documented suicide attempts among Regular Army soldiers during the study period. Individual-level person-month records from Army and Department of Defense administrative data systems were analyzed to identify socio-demographic, service-related, and mental health risk factors distinguishing suicide attempt cases from an equal-probability control sample of 183,826 person-months. Main Outcome and Measures Suicide attempts were identified using Department of Defense Suicide Event Report records and ICD-9 E95x diagnostic codes. Predictor variables were constructed from Army personnel and medical records. Results Enlisted soldiers accounted for 98.6% of all suicide attempts, with an overall rate of 377/100,000 person-years, versus 27.9/100,000 person-years for officers. Significant multivariate predictors among enlisted soldiers included socio-demographic characteristics (female gender, older age at Army entry, younger current age, low education, non-hispanic white), short length of service, never or previously deployed, and the presence and recency of mental health diagnoses. Among officers, only socio-demographic characteristics (female gender, older age at Army entry, younger current age, and low education) and the presence and recency of mental health diagnoses were significant. Conclusions and Relevance Results represent the most comprehensive accounting of U.S. Army suicide attempts to date and reveal unique risk profiles for enlisted soldiers and officers, and highlighting the

  18. A Multi-Depot Two-Echelon Vehicle Routing Problem with Delivery Options Arising in the Last Mile Distribution

    NARCIS (Netherlands)

    Zhou, Lin; Baldacci, Roberto; Vigo, Daniele; Wang, Xu

    2018-01-01

    In this paper, we introduce a new city logistics problem arising in the last mile distribution of e-commerce. The problem involves two levels of routing problems. The first requires a design of the routes for a vehicle fleet located at the depots to transport the customer demands to a subset of the

  19. Double stimuli-responsive polymer systems: How to use crosstalk between pH- and thermosensitivity for drug depots

    Czech Academy of Sciences Publication Activity Database

    Bogomolova, Anna; Kaberov, Leonid; Sedláček, Ondřej; Filippov, Sergey K.; Štěpánek, Petr; Král, V.; Wang, X. Y.; Liu, S. L.; Ye, X. D.; Hrubý, Martin

    2016-01-01

    Roč. 84, November (2016), s. 54-64 ISSN 0014-3057 R&D Projects: GA MŠk(CZ) LH14292; GA ČR(CZ) GC15-10527J Institutional support: RVO:61389013 Keywords : drug depot formulation * double responsive system * pH-responsive polymer Subject RIV: CC - Organic Chemistry Impact factor: 3.531, year: 2016

  20. Distribution of ganglionic sympathetic neurons supplying the subcutaneous, perirenal and mesentery fat tissue depots in the pig.

    Science.gov (United States)

    Czaja, Krzysztof; Kraeling, Robert; Klimczuk, Magdalena; Franke-Radowiecka, Amelia; Sienkiewicz, Waldemar; Lakomy, Mirosław

    2002-01-01

    Previous morphological studies revealed that the adipose tissue is innervated by adrenergic nerve fibers. Furthermore, physiological studies showed that the metabolism of adipose tissue is controlled by the adrenergic component of the nervous system. However, nothing is known on the sources of innervation of different fat tissue depots. Therefore, we decided to study the distribution of ganglionic sympathetic neurons innervating adipose tissue in the pig by means of a retrograde tracing method. We used 9 male and 9 female pigs of approximately 50 kg body weight. The retrograde tracer, Fast Blue (FB), was injected into the subcutaneous, perirenal and mesentery fat tissue depots. Results of the present study showed that numerous centers of the sympathetic nervous system innervate adipose tissue in the pig. FB+ neurons projecting to the subcutaneous fat tissue were placed in the thoraco-lumbar region of the sympathetic chain ganglia (SChG). However, neurons supplying perirenal and mesentery fat tissue depots were found in both the SChG and prevertebral ganglia (PVG). We conclude that different adipose tissue depots (subcutaneous, perirenal and mesentery) have different sources of innervation and that there is no significant difference in the distribution of neurons innervating adipose tissue in male and female pigs.

  1. After the Spring: Reforming Arab Armies

    Science.gov (United States)

    2014-09-01

    Arab region, and intercultural communication . She was previously assigned to the North Atlantic Treaty Organization (NATO) Defence College and the...and provides solutions to strategic Army issues affecting the national security community . The Peacekeeping and Stability Operations Institute...concern topics having strategic implications for the Army, the Department of Defense, and the larger national security community . In addition to its

  2. Army industrial, landscaping, and agricultural water use

    Energy Technology Data Exchange (ETDEWEB)

    Stoughton, Kate McMordie [Pacific Northwest National Laboratory (PNNL), Richland, WA (United States); Loper, Susan A. [Pacific Northwest National Laboratory (PNNL), Richland, WA (United States); Boyd, Brian K. [Pacific Northwest National Laboratory (PNNL), Richland, WA (United States)

    2014-09-18

    The Pacific Northwest National Laboratory conducted a task for the Deputy Assistant Secretary of the Army to quantify the Army’s ILA water use and to help improve the data quality and installation water reporting in the Army Energy and Water Reporting System.

  3. 32 CFR 631.14 - Army policy.

    Science.gov (United States)

    2010-07-01

    ...) Soldiers, military and/or Department of the Army Civilian (DAC) police performing off-installation... areas OCONUS. (b) Military and/or DAC police assigned to off-installation operations have the sole... under the command of, U.S. Army superiors. Military and DAC police may come to the aid of civilian law...

  4. Sustained analgesic effect of clonidine co-polymer depot in a porcine incisional pain model

    Directory of Open Access Journals (Sweden)

    Wilsey JT

    2018-04-01

    Full Text Available Jared T Wilsey, Julie H Block Medtronic Spine Division, Memphis, TN, USA Background: Previous research suggests that the α2 adrenergic agonist clonidine, a centrally acting analgesic and antihypertensive, may also have direct effects on peripheral pain generators. However, aqueous injections are limited by rapid systemic absorption leading to off target effects and a brief analgesic duration of action. Purpose: The aim of this study was to examine the efficacy of a sustained-release clonidine depot, placed in the wound bed, in a pig incisional pain model. Methods: The depot was a 15 mm ×5 mm ×0.3 mm poly(lactide-co-caprolactone polymer film containing 3% (w/w clonidine HCl (MDT3. Fifty-two young adult mix Landrace pigs (9–11 kg were divided into seven groups. All subjects received a 6 cm, full-thickness, linear incision into the left lateral flank. Group 1 served as a Sham control group (Sham, n=8. Group 2 received three placebo strips (PBO, n=8, placed end-to-end in the subcutaneous wound bed before wound closure. Group 3 received one MDT3 and two PBO (n=8, Group 4 received two MDT3 and one PBO (n=8, and Group 5 received three MDT3 (n=8. Positive control groups received peri-incisional injections of bupivacaine solution (Group 6, 30 mg/day bupivacaine, n=8 or clonidine solution (Group 7, 225 µg/day, n=4. Results: The surgical procedure was associated with significant peri-incisional tactile allodynia. There was a dose-dependent effect of MDT3 in partially reversing the peri-incisional tactile allodynia, with maximum pain relief relative to Sham at 72 hours. Daily injections of bupivacaine (30 mg, but not clonidine (up to 225 µg, completely reversed allodynia within 48 hours. There was a statistically significant correlation between the dose of MDT3 and cumulative withdrawal threshold from 4 hours through the conclusion of the study on day 7. Conclusion: These data suggest that a sustained-release clonidine depot may be a

  5. Why the Combined Field Army?

    Science.gov (United States)

    1989-03-31

    COMBINED FIELD ARMY A September 1988 article in the Wall Street Journal points out the arenas of change underway on the Korean peninsula.16 Many important...with superior results. ENDNOTES 16. Susan Moffat, "Koreans Demanding Equality on Defense", The Wall Street Journal ., 28 September 1988,p20. 17. This...p46. 20. Roh Address, p6. 21. Susan Moffat, " In Korea, Reunification is a Family Matter", The Wall Street Journal , 23 January 1989, pAl0. 22. Bunge

  6. US Army blood program: 2025 and beyond.

    Science.gov (United States)

    Gonzales, Richard; Taylor, Audra L; Atkinson, Andrew J; Malloy, Wilbur W; Macdonald, Victor W; Cap, Andrew P

    2016-03-01

    In preparing to support the Army in 2025 and beyond, the Army Blood Program remains actively engaged with the research and advanced development of blood products and medical technology to improve blood safety and efficacy in conjunction with the US Army Medical Research and Materiel Command. National and International Blood Bank authorities have noted that the US Army research and development efforts in providing new blood products and improving blood safety operate on the cutting edge of technology and are transformational for the global blood industry. Over the past 14 years, the Army has transformed how blood support is provided and improved the survival rate of casualties. Almost every product or process developed by or for the military has found an application in treating civilian patients. Conflicts have many unwanted consequences; however, in times of conflict, one positive aspect is the identification of novel solutions to improve the safety and efficacy of the blood supply. © 2015 AABB.

  7. Improving Inventory Management and Supply Chain of Diesel Fuel in Pertamina 5 Main Depots

    Directory of Open Access Journals (Sweden)

    Togar M Simatupang

    2012-01-01

    Full Text Available Planning Operation subdivision at PT Pertamina has to generate supply decisions includingmain depot to supply, supply point and transportation mode. However, the variability inplanning a supply schedule renders the process of determining a supply decision asineffective. The last assessment on uncertainties was done at 2006 and has not beenconsidered during decision making process. On the other hand, the result of this researchindicates that the uncertainty level is too high to be ignored and the poor informationexchange between the regional offices and the head office decreases the Planning Operation’sability to create plans that covers the company condition. This paper proposes an appropriatesafety stock to withstand the uncertainties and a supply scheduling process that also considersuncertainties by using Monte-Carlo Simulation with random numbers to simulate the events inthe upcoming period.Key words: inventory management, distribution planning, managing uncertainties, montecarlosimulation

  8. An Efficient and Benign Antimicrobial Depot Based on Silver-Infused MoS2.

    Science.gov (United States)

    Cao, Fangfang; Ju, Enguo; Zhang, Yan; Wang, Zhenzhen; Liu, Chaoqun; Li, Wei; Huang, Yanyan; Dong, Kai; Ren, Jinsong; Qu, Xiaogang

    2017-05-23

    Silver nanoparticles (AgNPs) have been used as a broad-spectrum antimicrobial agent, whose toxicity originates from the localized release of Ag + ions. However, the residual AgNPs core could generate potential risk to humans and waste of noble metals. Herein, we infused the cysteine-modified molybdenum disulfide with minimum Ag + ions and coated with a layer of cationic polyelectrolyte to construct an efficient and benign antimicrobial depot. The system exhibited much enhanced broad-spectrum antibacterial activity compared with an equivalent amount of silver nitrate, owing to its increasing accessibility of released Ag + to the cell walls of microorganisms. More importantly, the antibacterial system could be successfully applied to treat wound infection, while retaining high antibacterial activities, exhibiting negligible biotoxicity and avoiding the waste of Ag.

  9. Study on Multi-Depot Collaborative Transportation Problem of Milk-Run Pattern

    Directory of Open Access Journals (Sweden)

    Lou Zhenkai

    2016-01-01

    Full Text Available Analyze the relevance between Milk Run mode and collaborative transportation problem, put forward collaborative transportation problem of multiple-depot on Milk Run mode under the supply and demand separate nodes, consider the value of transport and transport costs, introduce the concept of node - arc flow, by comparing the size of traffic flow determine nodes collection, and then constructed multi-transport model of the problem. Considering one-way pickup and delivery closed, construct two-stage algorithm model, use dynamic programming recursive solution to determine the best route to pick up, and then solving delivery routing problem with different start and return point based on geometric method of Cosine. Finally use a numerical example illustrates the effectiveness of the algorithm and reasonable model.

  10. ERTS-1 DCS technical support provided by Wallops Station. [ground truth stations and DCP repair depot

    Science.gov (United States)

    Smith, R.

    1975-01-01

    Wallops Station accepted the tasks of providing ground truth to several ERTS investigators, operating a DCP repair depot, designing and building an airborne DCP Data Acquisition System, and providing aircraft underflight support for several other investigators. Additionally, the data bank is generally available for use by ERTS and other investigators that have a scientific interest in data pertaining to the Chesapeake Bay area. Working with DCS has provided a means of evaluating the system as a data collection device possibly applicable to ongoing Earth Resources Program activities in the Chesapeake Bay area as well as providing useful data and services to other ERTS investigators. The two areas of technical support provided by Wallops, ground truth stations and repair for DCPs, are briefly discussed.

  11. LEUPRORELIN ACETATE DEPOT (ELIGARD IN THE TREATMENT OF PROSTATE CANCER: WHAT DO PATIENTS WIN?

    Directory of Open Access Journals (Sweden)

    V. B. Matveev

    2014-08-01

    Full Text Available Eligard (leupropelin acetate, Atrigel delivery system is a synthetic analogue of luteinizing-hormone-realizing hormone (LHRH, which causes a rapid reduction in the level of testosterone to the concentration comparable with that after surgical castration. Eligard demonstrated a considerable advantage over other LHRH analogues in the depth of androgenic suppression and in the frequency of transient increases in testosterone levels at the beginning and during therapy. Eligard is available as 1-, 3-, and 6-month depot formulations, which allows a flexible approach to be applied to individually making up a therapy regimen. Eligard is as effective as castration therapy techniques. Treatment with this drug shows the low frequency of side effects and is well tolerated by patients.

  12. LEUPRORELIN ACETATE DEPOT (ELIGARD IN THE TREATMENT OF PROSTATE CANCER: WHAT DO PATIENTS WIN?

    Directory of Open Access Journals (Sweden)

    V. B. Matveev

    2010-01-01

    Full Text Available Eligard (leupropelin acetate, Atrigel delivery system is a synthetic analogue of luteinizing-hormone-realizing hormone (LHRH, which causes a rapid reduction in the level of testosterone to the concentration comparable with that after surgical castration. Eligard demonstrated a considerable advantage over other LHRH analogues in the depth of androgenic suppression and in the frequency of transient increases in testosterone levels at the beginning and during therapy. Eligard is available as 1-, 3-, and 6-month depot formulations, which allows a flexible approach to be applied to individually making up a therapy regimen. Eligard is as effective as castration therapy techniques. Treatment with this drug shows the low frequency of side effects and is well tolerated by patients.

  13. Leuprolide Acetate 1-Month Depot for Central Precocious Puberty: Hormonal Suppression and Recovery

    Directory of Open Access Journals (Sweden)

    Neely EKirk

    2011-01-01

    Full Text Available Methods. This prospective US multicenter trial of leuprolide acetate 1-month depot (7.5–15 mg for central precocious puberty utilized an open-label treatment period, long-term follow-up, and adult callback. Forty-nine females Results. Subjects were treated for years. Mean peak GnRH-stimulated LH and FSH were prepubertal after the first dose and remained suppressed throughout treatment. During treatment, mean estradiol decreased to the limit of detection and mean testosterone decreased but remained above prepubertal norms. During posttreatment follow-up ( years, all patients achieved a pubertal hormonal response within 1 year and menses were reported in all females ≥12 years old. No impairment of reproductive function was observed at adulthood (mean age: 24.8 years.

  14. Location and multi-depot vehicle routing for emergency vehicles using tour coverage and random sampling

    Directory of Open Access Journals (Sweden)

    Alireza Goli

    2015-09-01

    Full Text Available Distribution and optimum allocation of emergency resources are the most important tasks, which need to be accomplished during crisis. When a natural disaster such as earthquake, flood, etc. takes place, it is necessary to deliver rescue efforts as quickly as possible. Therefore, it is important to find optimum location and distribution of emergency relief resources. When a natural disaster occurs, it is not possible to reach some damaged areas. In this paper, location and multi-depot vehicle routing for emergency vehicles using tour coverage and random sampling is investigated. In this study, there is no need to visit all the places and some demand points receive their needs from the nearest possible location. The proposed study is implemented for some randomly generated numbers in different sizes. The preliminary results indicate that the proposed method was capable of reaching desirable solutions in reasonable amount of time.

  15. A case of mental retardation with paraphilia treated with depot leuprorelin.

    Science.gov (United States)

    Park, Woo Sung; Kim, Kyung Min; Jung, Yong Woo; Lim, Myung Ho

    2014-09-01

    Paraphilia is a psychiatric disease that has been difficult to cure. However, recently developed therapeutic methods hold promise. The patient was a 20-yr-old male with chief complaints of continuous masturbation, genital exposure, and aggressive behavior that started 2 yr ago. We administered leuprorelin 3.6 mg intramuscular injection per month, a depot gonadotrophin-releasing hormone analogue, to this patient who a severe mentally retardation with paraphilia. The clinical global impression (CGI)-severity, CGI-improvement and aberrant behavior checklist were performed. After one month, we observed significant improvement in symptoms, such as decreases of abnormal sexual behavior and sexual desire. The GnRH analogues are suggested to be used as an alternative or supplementary therapeutic method for sexual offenders after clinical studies.

  16. Developing a model for assessing biomass processing technologies within a local biomass processing depot.

    Science.gov (United States)

    Bals, Bryan D; Dale, Bruce E

    2012-02-01

    One solution to the supply chain challenges of cellulosic biofuels is a network of local biomass processing depots (LBPDs) that can produce stable, dense, intermediate commodities and valuable co-products prior to shipping to a refinery. A techno-economic model of an LBPD facility that could incorporate multiple technologies and products was developed in Microsoft Excel to be used to economically and environmentally evaluate potential LBPD systems. In this study, three technologies (ammonia fiber expansion or AFEX™ pretreatment, fast pyrolysis, and leaf protein processing) were assessed for profitability. Pyrolysis was slightly profitable under the base conditions, leaf protein processing was highly unprofitable, and AFEX was profitable if biomass drying was not required. This model can be adapted to multiple feedstocks and end uses, including both economic and environmental modeling. Copyright © 2011 Elsevier Ltd. All rights reserved.

  17. Stretch-Triggered Drug Delivery from Wearable Elastomer Films Containing Therapeutic Depots.

    Science.gov (United States)

    Di, Jin; Yao, Shanshan; Ye, Yanqi; Cui, Zheng; Yu, Jicheng; Ghosh, Tushar K; Zhu, Yong; Gu, Zhen

    2015-09-22

    Mechanical force-based stimulus provides a simple and easily accessible manner for spatiotemporally controlled drug delivery. Here we describe a wearable, tensile strain-triggered drug delivery device consisting of a stretchable elastomer and microgel depots containing drug loaded nanoparticles. By applying a tensile strain to the elastomer film, the release of drug from the microdepot is promoted due to the enlarged surface area for diffusion and Poisson's ratio-induced compression on the microdepot. Correspondingly, both sustained drug release by daily body motions and pulsatile release by intentional administration can be conveniently achieved. Our work demonstrated that the tensile strain, applied to the stretchable device, facilitated release of therapeutics from microdepots for anticancer and antibacterial treatments. Moreover, polymeric microneedles were further integrated with the stretch-responsive device for transcutaneous delivery of insulin and regulation of blood glucose levels of chemically induced type 1 diabetic mice.

  18. 77 FR 40030 - Army Science Board Summer Study Meeting

    Science.gov (United States)

    2012-07-06

    ... studies: Strategic Direction for Army Science and Technology and Small Unit Data to Decisions. Proposed Agenda: Thursday 26 July 2012: 1530-1630--The study results for Strategic Direction for Army Science and... DEPARTMENT OF DEFENSE Department of the Army Army Science Board Summer Study Meeting AGENCY...

  19. 75 FR 19302 - Radiation Sources on Army Land

    Science.gov (United States)

    2010-04-14

    ... DEPARTMENT OF DEFENSE Department of the Army 32 CFR Part 655 RIN 0702-AA58 [Docket No. USA-2008-0001] Radiation Sources on Army Land AGENCY: Department of the Army, DoD. ACTION: Proposed rule; request for comments. SUMMARY: The Department of the Army proposes to revise its regulations concerning...

  20. 76 FR 6692 - Radiation Sources on Army Land

    Science.gov (United States)

    2011-02-08

    ... DEPARTMENT OF DEFENSE Department of the Army 32 CFR Part 655 [Docket No. USA-2008-0001] RIN 0702-AA58 Radiation Sources on Army Land AGENCY: Department of the Army, DoD. ACTION: Final rule. SUMMARY: The Department of the Army is finalizing revisions to its regulation concerning radiation sources on...

  1. 77 FR 4026 - Army Education Advisory Subcommittee Meeting Notice

    Science.gov (United States)

    2012-01-26

    ... DEPARTMENT OF DEFENSE Department of the Army Army Education Advisory Subcommittee Meeting Notice... Visitors, U.S. Army War College Subcommittee. Date of Meeting: February 23, 2012. Place of Meeting: U.S. Army War College, 122 Forbes Avenue, Carlisle, PA, Command Conference Room, Root Hall, Carlisle...

  2. 77 FR 27209 - Army Education Advisory Subcommittee Meeting Notice

    Science.gov (United States)

    2012-05-09

    ... DEPARTMENT OF DEFENSE Department of the Army Army Education Advisory Subcommittee Meeting Notice...: Board of Visitors, U.S. Army War College Subcommittee. Date of Meeting: May 31, 2012. Place of Meeting: U.S. Army War College, 122 Forbes Avenue, Carlisle, PA, Command Conference Room, Root Hall, Carlisle...

  3. 78 FR 23759 - Army Education Advisory Subcommittee Meeting Notice

    Science.gov (United States)

    2013-04-22

    ... DEPARTMENT OF DEFENSE Department of the Army Army Education Advisory Subcommittee Meeting Notice... Visitors, U.S. Army War College Subcommittee. Dates of Meeting: May 16, 2013. Place of Meeting: U.S. Army War College, 122 Forbes Avenue, Carlisle, PA, Command Conference Room, Root Hall, Carlisle Barracks...

  4. [Job stress in locomotive attendants in a locomotive depot and related influencing factors].

    Science.gov (United States)

    Kang, L; Jia, X C; Lu, F; Zhou, W H; Chen, R

    2017-10-20

    Objective: To investigate the current status of job stress in locomotive attendants in a locomotive depot and related influencing factors. Methods: From 2012 to 2013, cluster sampling was used to select 1500 locomotive attendants in a locomotive depot in Zhengzhou Railway Bureau as respondents.The contents of the investigation included general data and occupational information.A job satisfaction questionnaire was used to investigate the degree of satisfaction, a depression scale was used to investigate the frequency of symptoms, and a daily stress scale was used to investigate the frequency of fatigue and stress. Results: There was a significant difference in depression score between locomotive attendants with different ages, working years, degrees of education, working situations of spouse, total monthly family incomes, numbers of times of attendanceat night, monthly numbers of times of attendance,ormonthly attendance times( P job satisfaction score between locomotive attendants with different ages,working years, degrees of education, working situations of spouse, total monthly family incomes, numbers of times of attendance at night, monthly attendance times,or ways to work( P job satisfaction( β =1.546)and monthly number of times of attendance,working years,attendance time at night,and degree of education were negatively correlated with job satisfaction( β =-0.185,-0.097,-0.020,and -1.106); monthly number of times of attendance andcommute time were positively correlated with depression( β =0.243 and 0.029); attendance time at night,working situation of spouse,commute time,monthly number of times of attendance,degree of education,and working years were positively correlated with daily stress( β =0.006,0.473,0.010,0.043,0.585, and 0.028). Conclusion: Number of times of attendance, attendance time,working years,and spouse are influencing factors for job stress in locomotive attendants. Improvement in work process and care for their personal life help to reduce

  5. N-Palmitoylethanolamine depot injection increased its tissue levels and those of other acylethanolamide lipids

    Directory of Open Access Journals (Sweden)

    Grillo SL

    2013-08-01

    Full Text Available Stephanie L Grillo,1,* Jantana Keereetaweep,2,* Michael A Grillo,1 Kent D Chapman,2 Peter Koulen1–3 1Vision Research Center, Department of Ophthalmology, School of Medicine, University of Missouri – Kansas City, Kansas City, MO, USA; 2University of North Texas, Center for Plant Lipid Research, Department of Biological Sciences, Denton, TX, USA; 3Department of Basic Medical Science, School of Medicine, University of Missouri – Kansas City, Kansas City, MO, USA *These authors contributed equally to this work Abstract: N-Palmitoylethanolamine (NAE 16:0 is an endogenous lipid signaling molecule that has limited water solubility, and its action is short-lived due to its rapid metabolism. This poses a problem for use in vivo as oral administration requires a high concentration for significant levels to reach target tissues, and injection of the compound in a dimethyl sulfoxide- or ethanol-based vehicle is usually not desirable during long-term treatment. A depot injection of NAE 16:0 was successfully emulsified in sterile corn oil (10 mg/kg and administered in young DBA/2 mice in order to elevate baseline levels of NAE 16:0 in target tissues. NAE 16:0 levels were increased in various tissues, particularly in the retina, 24 and 48 hours following injections. Increases ranged between 22% and 215% (above basal levels in blood serum, heart, brain, and retina and induced an entourage effect by increasing levels of other 18 carbon N-Acylethanolamines (NAEs, which ranged between 31% and 117% above baseline. These results indicate that NAE 16:0 can be used as a depot preparation, avoiding the use of inadequate vehicles, and can provide the basis for designing tissue-specific dosing regimens for therapies involving NAEs and related compounds. Keywords: cannabinoid receptor, vanilloid receptor, DBA/2 mice, lipid extraction, gas chromatography, mass spectrometry

  6. Army Hearing Program Talking Points Calendar Year 2016

    Science.gov (United States)

    2017-09-12

    provides summary information regarding the prevalence of hearing injury experienced by U.S. Army Soldiers in 2016. Soldiers who completed a DD Form...broken out by Service component and will be updated annually. TOTAL ARMY STATISTICS FOR CY16 24% of Soldiers have some degree of hearing...loss: 21% Active Duty 27% Army National Guard 28% Army Reserve 5% of Soldiers have a clinically significant hearing loss: 4% Active Duty 8% Army

  7. Army Hearing Program Status Report Quarter 2 Fiscal Year 2017

    Science.gov (United States)

    2017-07-01

    U.S. Army Publ ic Heal th Center Army Hearing Program Status Report Q2 FY17 Clinical Public Health and Epidemiology Directorate Army ...Hearing Division General Medical: 500A July 2017 Approved for public release; distribution unlimited Army Hearing Program Status Report, Q2FY17...56               INTRODUCTION The Army Hearing Program Status Report (AHPSR) is a component of the Public Health

  8. Improving Army Basic Research: Report of an Expert Panel on the Future of Army Laboratories

    Science.gov (United States)

    2012-01-01

    university-affiliated research center UCLA University of California, Los Angeles USACE U.S. Army Corps of Engineers VCSA Vice Chief of Staff of the Army WTC ...Capabilities Development, who provides recommendations to the one-star Warfighter Techni- cal Council ( WTC ). The WTC is co-chaired by the HQDA Director for...Service]-level members from Army laboratories, RDECs, and TRADOC Force Operating Capability leads. Results of both TD and WTC reviews are provided

  9. Atomic Army: the roles of the U.S. Army in America's nuclear endeavors

    OpenAIRE

    Womack, Seth M.

    2014-01-01

    Approved for public release; distribution is unlimited This thesis examines the roles of the U.S. Army in America’s nuclear undertakings. Since 1942, when the Army took responsibility for managing the Manhattan Project, the Army has made many important contributions to America’s nuclear endeavors. Its earliest nuclear roles included developing and employing America’s first nuclear weapons, executing nuclear counterproliferation missions, investigating the effects of nuclear weapons, and su...

  10. Genome-wide profiling of peroxisome proliferator-activated receptor γ in primary epididymal, inguinal, and brown adipocytes reveals depot-selective binding correlated with gene expression

    DEFF Research Database (Denmark)

    Siersbæk, Majken; Loft, Anne; Jørgensen, Mads Malik Aagaard

    2012-01-01

    epididymal, inguinal, and brown adipose tissues. While these PPARγ binding profiles are overall similar, there are clear depot-selective binding sites. Most PPARγ binding sites previously mapped in 3T3-L1 adipocytes can also be detected in primary adipocytes, but there are a large number of PPARγ binding...... sites that are specific to the primary cells, and these tend to be located in closed chromatin regions in 3T3-L1 adipocytes. The depot-selective binding of PPARγ is associated with highly depot-specific gene expression. This indicates that PPARγ plays a role in the induction of genes characteristic...... of different adipocyte lineages and that preadipocytes from different depots are differentially preprogrammed to permit PPARγ lineage-specific recruitment even when differentiated in vitro....

  11. Combined high dose vitamin C and E increases oxidative stress and visceral fat mass in rats treated by depot-medroxyprogesterone acetate

    Directory of Open Access Journals (Sweden)

    Endang Sri Wahyuni

    2016-12-01

    Conclusion: DMPA treatment induces oxidative stress in visceral fat. Combined high dose vitamin C and E increases oxidative stress and visceral fat mass in rats treated by depot-medroxyprogesterone acetate.

  12. Adesão ao tratamento e hospitalizações entre pacientes que realizam aplicações de Flufenazina Depot Adhesión al tratamiento y hospitalización entre pacientes que realizan aplicaciones de Flufenazina Depot Compliance with treatment and hospitalization among patients using Flufenazine Depot

    Directory of Open Access Journals (Sweden)

    José Menna Oliveira

    2003-08-01

    Full Text Available OBJETIVOS: Os autores revisam a bibliografia sobre medicação depot e apresentam dados referentes à adesão ao tratamento e hospitalizações entre os pacientes que realizam aplicações de enantato de flufenazina em regime ambulatorial no Hospital Espírita de Pelotas. MÉTODO: Analisaram-se os prontuários de pacientes que foram incluídos no regime depot anteriormente a maio de 2001 e que realizaram pelo menos uma aplicação entre maio de 2001 e junho de 2002, quanto à adesão ao tratamento e eventuais hospitalizações. RESULTADOS: De um total de 100 pacientes, 66 permaneciam em regime depot ao término do período estudado. Destes, 40 (61% apresentavam boa adesão ao tratamento, enquanto 26 (39% apresentavam má adesão. Houve um total de 25 pacientes que sofreram hospitalizações, entre os quais a maioria não estava em tratamento no término do estudo ou apresentava má adesão. Entre os pacientes procedentes do mesmo bairro em que se situa o hospital, 10 (67% apresentavam boa adesão em comparação com 30 pacientes (59% procedentes de bairros distintos. DISCUSSÃO: O número de hospitalizações variou visivelmente, conforme a permanência ou não em tratamento e a adesão ao mesmo. Pacientes provenientes de bairros distantes do hospital tenderam a apresentar pior adesão ao tratamento. CONCLUSÕES: É possível que pacientes em regime de aplicação depot residentes próximos ao local de aplicação beneficiem-se mais do tratamento que aqueles residentes em locais distantes. São necessários mais estudos comparando administrações depot com VO em termos de adesão e investigando fatores preditores de boa adesão ao tratamento.OBJETIVOS: Los autores revisan la bibliografía sobre medicación depot y presentan datos referentes a la adhesión al tratamiento y hospitalizaciones entre los pacientes que realizan aplicaciones de enantato de flufenazina en régimen ambulatorio en el Hospital Espiritista de Pelotas. MÉTODO: Fueron

  13. Developing an Army Market Research Index in Support of Army Recruiting

    National Research Council Canada - National Science Library

    Morath, Ray

    2001-01-01

    .... Generating appropriate market research for the Army requires first cataloguing the existing market research databases and identifying the critical questions that are not answered by current research...

  14. Army's drinking water surveillance program

    International Nuclear Information System (INIS)

    Sneeringer, P.V.; Belkin, F.; Straffon, N.; Costick, S.A.

    1977-01-01

    In 1976 a total of 827 water sources from Army installations throughout the world were sampled and analyzed for 53 chemical constituents and physical parameters. Medically significant contaminants included radiation measurements, heavy metals, fluoride, nitrate, and pesticides. Radiological activity appeared to vary with geographic location; a majority being from water sources in the western part of the U.S. No results for tritium were found to exceed the health-reference limit. Confirmatory analyses for radium-226 identified 3 groundwater sources as exceeding the limit; one was attributed to natural activity and the other sources are currently being investigated. Of the metals considered to be medically significant, mercury, chromium, lead, cadmium, silver, barium and arsenic were found in amounts within health level limits. Nitrate levels exceeding the health limit were confirmed for 2 drinking water sources

  15. Contrasting Cellularity and Fatty Acid Composition in Fat Depots from Alentejana and Barrosã Bovine Breeds Fed High and Low Forage Diets

    Science.gov (United States)

    Costa, Ana S.H.; Lopes, Paula A.; Estevão, Marta; Martins, Susana V.; Alves, Susana P.; Pinto, Rui M.A.; Pissarra, Hugo; Correia, Jorge J.; Pinho, Mário; Fontes, Carlos M.G.A.; Prates, José A.M.

    2012-01-01

    During the finishing phase of bovines, large amounts of subcutaneous and visceral fats are deposited leading to production inefficiencies with major impact on meat quality. A better understanding of the cellularity features of the main fat depots could provide strategies for adipose tissue manipulation. This study assessed the effect of feeding diets with distinct forage to concentrate ratios on the cellularity of two fat depots of beef cattle and their implications on the fatty acid profile. Thus, two phylogenetically distant Portuguese bovine breeds, Alentejana and Barrosã, were selected. The results did not show differences in subcutaneous fat deposition nor in visceral fat depots partitioning. Plasma adipokines concentration failed to show a consistent relationship with fatness, as leptin remained constant in all experimental groups, whereas interleukin-6 was influenced by breed. Fat depot seems to determine the area and number of adipocytes, with larger adipocytes and a lower number of cells in subcutaneous fat than in mesenteric fat. Neither breed nor diet influenced adipocytes area and number. The contents of total fatty acids, partial sums of fatty acids and conjugated linoleic acid isomeric profile were affected by breed and fat depot. The incorporation of saturated fatty acids (SFA), trans fatty acids, polyunsaturated fatty acids (PUFA) and branched chain fatty acids (BCFA) was higher in mesenteric fat depot, whereas subcutaneous fat depot had greater percentages of monounsaturated fatty acids (MUFA). In addition, SFA and MUFA proportions seem to be breed-related. In spite of the less relevant role of diet, the percentages of PUFA and BCFA were influenced by this factor. Under these experimental conditions, the effect of fat depot on cellularity and fatty acid composition prevails over breed or diet, as reinforced by the principal component analysis. PMID:22253565

  16. Preliminary Assessment/Site Investigation: Tooele Army Depot, Utah. Volume 1. North Area and Facilities at Hill Air Force Base. Appendixes

    Science.gov (United States)

    1988-12-01

    A 2-ftrophen@l 2NF 400 -0 * 4-hag Nhel ANF 350 r -a.10r0-*cr*SoI 4CL3C 400-------------------------- * pentgao2rophoe -C 350 GA fhencl PFE ?;,OG1T15...m -RI) Very LOose 5 blows/ft or less Loose 6-i0 blows/ft Medium Dense 11-30 blows/ft Dense 31-50 blows/ft Very Dense 51 blows/ft or more ( Clay . Slit...30 blows/ft Dense 31-50 blows/ft Very Dense 51 blows/ft or more ( Clay , Slit. Od Coubintions) ConsistenIcy Descriptive Very Soft 3 blows/ft or less

  17. Results of a Microbial Weathering Study of Composted Explosives-Contaminated Soil Obtained from the Umatilla Army Depot Activity, Umatilla, Oregon

    National Research Council Canada - National Science Library

    Broder, M

    1998-01-01

    ... and 26.4 ppb of HMX and RDX, respectively. These results suggest that these explosives were not fully mineralized. However, the concentrations leached were well below the state of Oregon's action limit of 30 ppm.

  18. Energy Assessment at Army Installations in Germany: Campbell Barracks - Heidelberg, Coleman Barracks - Manheim, Katterbach Barracks - Ansbach, Storch Barracks - Illesheim, and U.S. Depot - Germersheim

    Science.gov (United States)

    2009-06-01

    report are not to be used for advertising , publication, or promotional purposes. Citation of trade names does not constitute an official endorsement or...113 75 Positioning of modules in an open space – PV-system ......................................................113 76 Large door at old Nike Bldg...Germersheim BE #3US – Reduce door size Bldgs 7938 and 7941 Existing conditions In two of the old Nike Storage Bldgs (7938 and 7941), there are three

  19. Tooele Army Depot - South Area Suspected Releases Units RCRA Facility Investigation - Phase II for SWMUs 1, 25, and 37. Appendices: D-M

    Science.gov (United States)

    1995-11-01

    Moquin) Stanley Shad-scale Atriplex rosea L. Shad-scale, Saltbrush Ceratoides lanata (Pursh) Howell Winter Fat [=Eurotia lanata] Kochia americana Watson...Primrose Family Cenothera caespitosa Nuttall Evening-Primrose Oenothera biennis L. Common Evening Primrose Geraniaceae Geranium Family Erodium cicutarium

  20. Results of a Study Investigating the Plant Uptake of Explosive Residues From Compost of Explosives-Contaminated Soil Obtained from the Umatilla Army Depot Activity

    Science.gov (United States)

    1998-11-01

    brown color due to the presence of humic compounds, tannin resins, and other organic acids. These compounds represented the water-soluble fraction of...recovery of mercury from spiked samples. 3.3 Seawaters, brines, and industrial effluents high in chlorides require additional permanganate (as much as 25...whether the carbon measurement is made on a sewage plant effluent , industrial waste, or on water taken directly from the stream. In this light

  1. Transport and Fate of Nitroaromatic and Nitramine Explosives in Soil from Open Burning/Open Detonation Operations: Anniston Army Depot (AAD)

    Science.gov (United States)

    1993-12-01

    entitled Toxicity of Selected Munitions and Munition-Contaminated soil to the Earthworm Eisenia foetida ). 7 In task 3, soil/water extracts were prepared...R.S. Wentsel. Toxicity of Selected Munitions and Munition- Contaminated Soil on the Earthworm ( Eisenia FoetidIa); Technical Report ERDEC-TR-037, April

  2. Site Safety and Health Plan (SSHP) for a Transportable Incineration System (TIS) at the Savanna Army Depot Activity (SADA), Washout Lagoon Area. Appendices

    Science.gov (United States)

    1991-03-08

    Corporation Page 1 of 4 PRODUCT: Acetylene L-4559-E 3 April 1987 THRESHOLD LIMIT VALUE: Acetylene - Simple asphyxiant ACGIH 1986-87; Acetone, 750ppm ACGIH...Reasonably expected constituents of the fume would include: complex oxides of .iron, manganese, s-4liqon, titanium. Fluorides would also be present...7631-86-9 5 3 TITANIUM OXIDE 13463-67-7 15 10,20 STEL** FLUORIDES 2.5(as F) 2.5 (as F) *CL - Ceiling Limit **STEL - Short Term Exposure Limit Gaseous

  3. Phase II RCRA Facility Investigation Report, Tooele Army Depot-North Area, Group A, Suspected Releases SWMUs; Volume 2 - Appendices A-K

    National Research Council Canada - National Science Library

    1997-01-01

    ... field activities were conducted, and descriptions of sample collection, handling, and shipping procedures. The Phase II RFI field activities were conducted without significant deviation from the project work plans prepared for this investigation...

  4. The Hereptofauna of Letterkenny Army Depot, South-Central Pennsylvania: A Starting Point to the Long-Term Monitoring and Management of Amphibians and Reptiles

    Science.gov (United States)

    2010-06-01

    77°42’W. this holding is composed of mild hills and valleys that range 180 to 309 m in elevation with a variety of wetlands such as creeks...sector of the installation at the base of North Mountain along the Kittatinny ridge of the Blue Mountain range . federal protec- tion, and the...Nerodia sipedon Y Y N Y Storeria dekayi Y Y N N Storeria occipitomaculata Y Y N N Thamnophis sauritus Y Y N Y Thamnophis sirtalis Y Y Y Y Thamnophis

  5. Operational Army Reserve Implications for Organizational Health

    National Research Council Canada - National Science Library

    Dahms, Jonathan A

    2007-01-01

    The Army Reserve has been in a constant state of mobilization since 1995 with the advent of the Bosnia crisis and the pace of mobilization increased exponentially after the terrorist attacks of September 11, 2001...

  6. Trust and Dialogue in the Army Profession

    National Research Council Canada - National Science Library

    Lewis, III, James M

    2008-01-01

    .... Trust binds the Army together as a cohesive unit. Unfortunately, in the Officer Corps there is the perception of a serious erosion of trust that may be reaching dangerously dysfunctional levels...

  7. US Army Cultural Obstacles to Transformational Leadership

    National Research Council Canada - National Science Library

    Combs, Peggy C

    2007-01-01

    ...." Although these words sound like a direct lift of the current 2007 Army Posture statement, which discusses the "pentathlete" leader, they were written by the 33rd CSA, General Dennis Reimer, in 1999...

  8. Characterizing Extreme Environments for Army Testing

    National Research Council Canada - National Science Library

    Harmon, R. S; King, W. C; Palka, Eugene J; Gilewitch, Daniel A

    2004-01-01

    Army Regulation (AR) 70-38 publishes standards for temperature and humidity in different environments, but there are other important environmental features such as general climate, terrain character, and biological...

  9. Accelerated Logistics: Streamlining the Army's Supply Chain

    National Research Council Canada - National Science Library

    Wang, Mark

    2000-01-01

    ...) initiative, the Army has dramatically streamlined its supply chain, cutting order and ship times for repair parts by nearly two-thirds nationwide and over 75 percent at several of the major Forces Command (FORSCOM) installations...

  10. A Pilotless Army in the Megalopolis

    National Research Council Canada - National Science Library

    Wegner, Robert

    2004-01-01

    This monograph answers the question, "Can unmanned aerial vehicles (UAVs) supplant manned United States Army attack and reconnaissance helicopters in the conduct of future urban operations" and the answer is, "not completely...

  11. Transformation and the Army School System

    National Research Council Canada - National Science Library

    Shanley, Michael G; Crowley, James C; Lewis, Matthew W; Masi, Ralph; Straus, Susan G; Leuschner, Kristin J; Hartman, Steven; Stockly, Sue

    2005-01-01

    .... The study recommends that the Army adopt private-sector models in developing interactive media instruction, develop a more effective local school system to better meet future unit training needs...

  12. An Ant Colony Optimization algorithm for solving the fixed destination multi-depot multiple traveling salesman problem with non-random parameters

    Science.gov (United States)

    Ramadhani, T.; Hertono, G. F.; Handari, B. D.

    2017-07-01

    The Multiple Traveling Salesman Problem (MTSP) is the extension of the Traveling Salesman Problem (TSP) in which the shortest routes of m salesmen all of which start and finish in a single city (depot) will be determined. If there is more than one depot and salesmen start from and return to the same depot, then the problem is called Fixed Destination Multi-depot Multiple Traveling Salesman Problem (MMTSP). In this paper, MMTSP will be solved using the Ant Colony Optimization (ACO) algorithm. ACO is a metaheuristic optimization algorithm which is derived from the behavior of ants in finding the shortest route(s) from the anthill to a form of nourishment. In solving the MMTSP, the algorithm is observed with respect to different chosen cities as depots and non-randomly three parameters of MMTSP: m, K, L, those represents the number of salesmen, the fewest cities that must be visited by a salesman, and the most number of cities that can be visited by a salesman, respectively. The implementation is observed with four dataset from TSPLIB. The results show that the different chosen cities as depots and the three parameters of MMTSP, in which m is the most important parameter, affect the solution.

  13. The Utility of Ada for Army Modeling

    Science.gov (United States)

    1990-04-10

    34 Ada " for Ada Lovelace (1815-1851), a mathematician who worked with Charles Babbage on his difference and analytic engines.9 Later in 1979, the HOLWG...OF ADA FOR ARMY MODELING BY COLONEL MICHAEL L. YOCOM DISTRIBUTION STATEMENT A: Approved for publie releases distribution is unlimited. 1% LF-, EC TE...TITLE (ad Subtitle) a. TYPE OF REPORT & PERIOD COVERED The Utility of Ada for Army Modeling Individual Study Project 6 PERFORMING ORG. REPORT NUMBER

  14. Making Weapons for the Terracotta Army

    OpenAIRE

    Marcos Martinón-Torres; Xiuzhen Janice Li; Andrew Bevan; Yin Xia; Zhao Kun; Thilo Rehren

    2011-01-01

    The Terracotta Army of the First Emperor of China is one of the most emblematic archaeological sites in the world. Many questions remain about the logistics of technology, standardisation and labour organisation behind the creation of such a colossal construction in just a few decades over 2,000 years ago. An ongoing research project co-ordinated between the UCL Institute of Archaeology and the Emperor Qin Shihang's Terracotta Army Museum is beginning to address some of these questions. This ...

  15. Decisive Army Strategic and Expeditionary Maneuver

    Science.gov (United States)

    2015-05-01

    Committee organized under the Federal Advisory Committee Act. The purpose of the study was to help update the Army’s strategy and doctrine around the...acquisition systems ( SCADA ), a new security paradigm will be needed for access control. To illustrate these points, in large commercial enterprise...Lift Update ,” PowerPoint Presentation, 5 December 2013. 6. Army Capabilities Integration Center (ARCIC), Unified Quest 2013: Deep Future Wargame

  16. Department of the Army Installation Restoration Program

    International Nuclear Information System (INIS)

    Anderson, A.W.

    1988-01-01

    The Army's Installation Restoration Program (IRP) was established in 1975 in response to regulatory action at several installations where past disposal practices had caused contamination of streams and groundwater. The need to decontaminate excess Army-owned real estate also was considered in early IRP activities. A variety of site types have been discovered on Army installations. The major site types evaluated to date include: contaminated soil areas, landfills, lagoons, buildings, burning grounds, sumps, pits, storage tanks, sewage treatment plants, storage pads, industrial wastewater treatment plants, and salvage yards. Twenty Army installations have been proposed for or listed on the National Priorities List (NPL). The need for taking action at hazardous waste sites, however, is based on threats they pose to human health, welfare or the environment. Sites do not have to be on the SPL in order to be cleaned up through IRP activities. All of the sites that caused Army installations to be proposed for the NPL are being evaluated and cleaned up. In addition, all Army properties have been or will be assessed and where needed they will be addressed by the IRP

  17. Fat depot-specific gene signature and ECM remodeling of Sca1(high) adipose-derived stem cells.

    Science.gov (United States)

    Tokunaga, Masakuni; Inoue, Mayumi; Jiang, Yibin; Barnes, Richard H; Buchner, David A; Chun, Tae-Hwa

    2014-06-01

    Stem cell antigen-1 (Sca1 or Ly6A/E) is a cell surface marker that is widely expressed in mesenchymal stem cells, including adipose-derived stem cells (ASCs). We hypothesized that the fat depot-specific gene signature of Sca1(high) ASCs may play the major role in defining adipose tissue function and extracellular matrix (ECM) remodeling in a depot-specific manner. Herein we aimed to characterize the unique gene signature and ECM remodeling of Sca1(high) ASCs isolated from subcutaneous (inguinal) and visceral (epididymal) adipose tissues. Sca1(high) ASCs are found in the adventitia and perivascular areas of adipose tissues. Sca1(high) ASCs purified with magnetic-activated cell sorting (MACS) demonstrate dendrite or round shape with the higher expression of cytokines and chemokines (e.g., Il6, Cxcl1) and the lower expression of a glucose transporter (Glut1). Subcutaneous and visceral fat-derived Sca1(high) ASCs particularly differ in the gene expressions of adhesion and ECM molecules. While the expression of the major membrane-type collagenase (MMP14) is comparable between the groups, the expressions of secreted collagenases (MMP8 and MMP13) are higher in visceral Sca1(high) ASCs than in subcutaneous ASCs. Consistently, slow but focal MMP-dependent collagenolysis was observed with subcutaneous adipose tissue-derived vascular stromal cells, whereas rapid and bulk collagenolysis was observed with visceral adipose tissue-derived cells in MMP-dependent and -independent manners. These results suggest that the fat depot-specific gene signatures of ASCs may contribute to the distinct patterns of ECM remodeling and adipose function in different fat depots. Copyright © 2014 International Society of Matrix Biology. Published by Elsevier B.V. All rights reserved.

  18. Endurance exercise training induces fat depot-specific differences in basal autophagic activity

    International Nuclear Information System (INIS)

    Tanaka, Goki; Kato, Hisashi; Izawa, Tetsuya

    2015-01-01

    The purpose of this study was to uncover the effect of exercise training on the expression of autophagy marker proteins in epididymal white adipose tissue (eWAT), inguinal WAT (iWAT), and the stromal vascular fraction (SVF) collected from eWAT. Male Wistar rats aged 4–5 weeks were randomly divided into two groups, sedentary control (n = 7) and exercise-trained (n = 7). Rats in the exercise-trained group were exercised on a treadmill set at a 5° incline 5 days/week for 9 weeks. We determined that the expression levels of an autophagosome-associating form of microtubule-associated protein 1 light chain 3 (LC3)-II and of p62 were significantly higher in eWAT from exercise-trained than from control rats, while those of adipose-specific deletion of autophagy-related protein (ATG7) and lysosomal-associated membrane protein type 2A (LAMP2a) showed no difference between groups. However, in iWAT, the expression levels of LC3-II and ATG7 were significantly higher in exercise-trained than in control rats. The expression of p62 was highly correlated with that of peroxisome proliferator-activated receptor γ (PPARγ), a master regulator of adipogenesis and lipid metabolism, in both WAT types (eWAT, r = 0.856, P < 0.05; iWAT, r = 0.762, P < 0.05), whereas LC3-II and PPARγ levels were highly correlated in eWAT (r = 0.765, P < 0.05) but not in iWAT (r = −0.306, ns). In SVF, the expression levels of LC3II, ATG7, and LAMP2a were significantly higher in exercise-trained than in control rats. These results suggest that exercise training suppresses basal autophagy activity in eWAT, but that this activity is enhanced in iWAT and SVF collected from eWAT. Thus, the adaptation of basal autophagic activity following exercise training exhibits fat depot-specific differences. - Highlights: • Autophagy has been associated with obesity and associated diseases. • We examined exercise-associated rat white adipose tissue (WAT) autophagy markers. • Exercise increased

  19. Endurance exercise training induces fat depot-specific differences in basal autophagic activity

    Energy Technology Data Exchange (ETDEWEB)

    Tanaka, Goki; Kato, Hisashi; Izawa, Tetsuya, E-mail: tizawa@mail.doshisha.ac.jp

    2015-10-23

    The purpose of this study was to uncover the effect of exercise training on the expression of autophagy marker proteins in epididymal white adipose tissue (eWAT), inguinal WAT (iWAT), and the stromal vascular fraction (SVF) collected from eWAT. Male Wistar rats aged 4–5 weeks were randomly divided into two groups, sedentary control (n = 7) and exercise-trained (n = 7). Rats in the exercise-trained group were exercised on a treadmill set at a 5° incline 5 days/week for 9 weeks. We determined that the expression levels of an autophagosome-associating form of microtubule-associated protein 1 light chain 3 (LC3)-II and of p62 were significantly higher in eWAT from exercise-trained than from control rats, while those of adipose-specific deletion of autophagy-related protein (ATG7) and lysosomal-associated membrane protein type 2A (LAMP2a) showed no difference between groups. However, in iWAT, the expression levels of LC3-II and ATG7 were significantly higher in exercise-trained than in control rats. The expression of p62 was highly correlated with that of peroxisome proliferator-activated receptor γ (PPARγ), a master regulator of adipogenesis and lipid metabolism, in both WAT types (eWAT, r = 0.856, P < 0.05; iWAT, r = 0.762, P < 0.05), whereas LC3-II and PPARγ levels were highly correlated in eWAT (r = 0.765, P < 0.05) but not in iWAT (r = −0.306, ns). In SVF, the expression levels of LC3II, ATG7, and LAMP2a were significantly higher in exercise-trained than in control rats. These results suggest that exercise training suppresses basal autophagy activity in eWAT, but that this activity is enhanced in iWAT and SVF collected from eWAT. Thus, the adaptation of basal autophagic activity following exercise training exhibits fat depot-specific differences. - Highlights: • Autophagy has been associated with obesity and associated diseases. • We examined exercise-associated rat white adipose tissue (WAT) autophagy markers. • Exercise increased

  20. Quantification of abdominal fat depots in rats and mice during obesity and weight loss interventions.

    Directory of Open Access Journals (Sweden)

    Bhanu Prakash Kn

    Full Text Available BACKGROUND & AIMS: Obesity is a leading healthcare issue contributing to metabolic diseases. There is a great interest in non-invasive approaches for quantitating abdominal fat in obese animals and humans. In this work, we propose an automated method to distinguish and quantify subcutaneous and visceral adipose tissues (SAT and VAT in rodents during obesity and weight loss interventions. We have also investigated the influence of different magnetic resonance sequences and sources of variability in quantification of fat depots. MATERIALS AND METHODS: High-fat diet fed rodents were utilized for investigating the changes during obesity, exercise, and calorie restriction interventions (N = 7/cohort. Imaging was performed on a 7T Bruker ClinScan scanner using fast spin echo (FSE and Dixon imaging methods to estimate the fat depots. Finally, we quantified the SAT and VAT volumes between the L1-L5 lumbar vertebrae using the proposed automatic hybrid geodesic region-based curve evolution algorithm. RESULTS: Significant changes in SAT and VAT volumes (p<0.01 were observed between the pre- and post-intervention measurements. The SAT and VAT were 44.22±9%, 21.06±1.35% for control, -17.33±3.07%, -15.09±1.11% for exercise, and 18.56±2.05%, -3.9±0.96% for calorie restriction cohorts, respectively. The fat quantification correlation between FSE (with and without water suppression sequences and Dixon for SAT and VAT were 0.9709, 0.9803 and 0.9955, 0.9840 respectively. The algorithm significantly reduced the computation time from 100 sec/slice to 25 sec/slice. The pre-processing, data-derived contour placement and avoidance of strong background-image boundary improved the convergence accuracy of the proposed algorithm. CONCLUSIONS: We developed a fully automatic segmentation algorithm to quantitate SAT and VAT from abdominal images of rodents, which can support large cohort studies. We additionally identified the influence of non-algorithmic variables

  1. Randomised controlled single-blind study of conventional versus depot mydriatic drug delivery prior to cataract surgery

    Directory of Open Access Journals (Sweden)

    Madge Simon

    2006-11-01

    Full Text Available Abstract Background A prerequisite for safe cataract surgery is an adequately dilated pupil. The authors conducted a trial to assess the efficacy (in terms of pupil diameter of a depot method of pre-operative pupil dilatation, as compared with repeated instillations of drops (which is time-consuming for the nursing staff and uncomfortable for the patient. Methods A prospective randomised masked trial was conducted comprising 130 patients with no significant ocular history undergoing elective clear corneal phacoemulsification. 65 patients had mydriatic drops (Tropicamide 1%, Phenylephrine 2.5%, Diclofenac sodium 0.1% instilled prior to surgery, 65 had a wick soaked in the same drop mixture placed in the inferior fornix. Horizontal pupil diameters were recorded on a millimetre scale immediately prior to surgery. Results There was no significant difference in pupil size between the two groups (p = 0.255, Student's t-test. Conclusion There was no significant difference between the mydriasis obtained with the depot system compared with conventional drop application. Use of a depot mydriatic delivery system appears to be a safe and efficient method of drug delivery. Trial Registration International Standard Randomised Controlled Trial Number Register ISRCTN78047760

  2. Increasing Responsiveness of the Army Rapid Acquisition Process: The Army Rapid Equipping Force

    Science.gov (United States)

    2011-06-01

    74 Rodney Spann , REF Logistics Management Division Brief, 29 March 2010, Slide 2. 75 Dickson, U.S. Army Rapid Equipping Force 2002-2007 Booklet, 82...speech at the Sorbonne, Paris, April 23, 1910. Spann , Rodney, REF Logistics Management Division Brief, Slide 2, 29 March 2010. U.S. Army 20 th

  3. Atomic Army: The Roles of the U.S. Army in America’s Nuclear Endeavors

    Science.gov (United States)

    2014-09-01

    ROAD Reorganization Objectives Army Division ROK Republic of Korea SACEUR Supreme Allied Commander, Europe SADM Special Atomic Demolition Munitions...been able to construct a nuclear bomb without the contributions of dedicated and ingenious civilian scientists, engineers, and technicians or the...Reorganization Objectives Army Division ( ROAD ).369 ROADs typically consisted of three brigades armed with both nuclear and conventional weapons, and they

  4. A Dutch mass army? Dutch liberal ideas and practices to enlarge the army, 1914-1922

    NARCIS (Netherlands)

    Klinkert, W.

    2011-01-01

    In August 1914, the Dutch government called up its citizens to enlist voluntarily in the army. This call-up failed. In 1915, the government tried to enlarge the army significantly by law. This attempt succeeded partially. At the end of the war, under threat of a leftwing revolution, the Netherlands

  5. 2014 Center for Army Leadership Annual Survey of Army Leadership (CASAL): Military Leader Findings

    Science.gov (United States)

    2015-09-22

    quality of military leadership . Implicit leadership theory (Eden & Leviatan, 1975; Yukl, 7 The...Eden, D., & Leviatan, U. (1975). Implicit leadership theory as a determinant of the factor structure underlying supervisory behavior scales. Journal...2014 CENTER FOR ARMY LEADERSHIP ANNUAL SURVEY OF ARMY LEADERSHIP (CASAL): MILITARY LEADER FINDINGS TECHNICAL REPORT 2015-01

  6. Disposal of chemical agents and munitions stored at Pueblo Depot Activity, Colorado. Final, Phase 1: Environmental report

    Energy Technology Data Exchange (ETDEWEB)

    Terry, J.W.; Blasing, T.J.; Ensminger, J.T.; Johnson, R.O.; Schexnayder, S.M.; Shor, J.T.; Staub, W.P.; Tolbert, V.R.; Zimmerman, G.P.

    1995-04-01

    Under the Chemical Stockpile Disposal Program (CSDP), the US Army proposes to dispose of lethal chemical agents and munitions stored at eight existing Army installations in the continental United States. In 1988, the US Army issued the final programmatic environmental impact statement (FPEIS) for the CSDP. The FPEIS and the subsequent Record of Decision (ROD) identified an on-site disposal process as the preferred method for destruction of the stockpile. That is, the FPEIS determined the environmentally preferred alternative to be on-site disposal in high-temperature incinerators, while the ROD selected this alternative for implementation as the preferred method for destruction of the stockpile. In this Phase I report, the overall CSDP decision regarding disposal of the PUDA Stockpile is subjected to further analyses, and its validity at PUDA is reviewed with newer, more detailed data than those providing the basis for the conclusions in the FPEIS. The findings of this Phase I report will be factored into the scope of a site-specific environmental impact statement to be prepared for the destruction of the PUDA stockpile. The focus of this Phase I report is on those data identified as having the potential to alter the Army`s previous decision regarding disposal of the PUDA stockpile; however, several other factors beyond the scope of this Phase I report must also be acknowledged to have the potential to change or modify the Army`s decisions regarding PUDA.

  7. Scaling up depot medroxyprogesterone acetate (DMPA): a systematic literature review illustrating the AIDED model.

    Science.gov (United States)

    Curry, Leslie; Taylor, Lauren; Pallas, Sarah Wood; Cherlin, Emily; Pérez-Escamilla, Rafael; Bradley, Elizabeth H

    2013-08-02

    Use of depot medroxyprogesterone acetate (DMPA), often known by the brand name Depo-Provera, has increased globally, particularly in multiple low- and middle-income countries (LMICs). As a reproductive health technology that has scaled up in diverse contexts, DMPA is an exemplar product innovation with which to illustrate the utility of the AIDED model for scaling up family health innovations. We conducted a systematic review of the enabling factors and barriers to scaling up DMPA use in LMICs. We searched 11 electronic databases for academic literature published through January 2013 (n = 284 articles), and grey literature from major health organizations. We applied exclusion criteria to identify relevant articles from peer-reviewed (n = 10) and grey literature (n = 9), extracting data on scale up of DMPA in 13 countries. We then mapped the resulting factors to the five AIDED model components: ASSESS, INNOVATE, DEVELOP, ENGAGE, and DEVOLVE. The final sample of sources included studies representing variation in geographies and methodologies. We identified 15 enabling factors and 10 barriers to dissemination, diffusion, scale up, and/or sustainability of DMPA use. The greatest number of factors were mapped to the ASSESS, DEVELOP, and ENGAGE components. Findings offer early empirical support for the AIDED model, and provide insights into scale up of DMPA that may be relevant for other family planning product innovations.

  8. ANALISIS HIGIENE SANITASI DEPOT AIR MINUM ISI ULANG (DAMIU DI SEKITAR UNIVERSITAS ISLAM RIAU

    Directory of Open Access Journals (Sweden)

    Fitri Mairizki

    2017-10-01

    Full Text Available The existence of Drinking Water Refill Depot (DAMIU continues to increase appropriate with the dynamics of community needs for drinking water that has good quality and safe for consumption. Although it had a low price, not all DAMIU product guaranteed safety. DAMIU  as  an alternative choice to fulfill the community needs for drinking water becomes a risk that harmful to health if consumers did  not pay attention in DAMIU hygiene and sanitation. Therefore, the purpose of this study was to analyze hygiene and sanitation of  DAMIU building, equipment and operator. The type of this research was descriptive research.The data obtained in this study was primary data in the form of observation using checklist sheet. The data was presented in tabular form and discussed descriptively. In general, hygiene and sanitation of DAMIU building and equipment were good but the sanitation facilities still minimals, the wash basin for operators and its tools were not available. There were  several of operators hygiene must be considered. All operators did not using special uniform for work, did not conducting periodic medical examinations and did not have sertificate of hygiene sanitation course.

  9. Behavior of Particle Depots in Molten Silicon During Float-Zone Growth in Strong Magnetic Fields

    Science.gov (United States)

    Jauss, T.; Croell, A.; SorgenFrei, T.; Azizi, M.; Reimann, C.; Friedrich, J.; Volz, M. P.

    2014-01-01

    Solar cells made from directionally solidified silicon cover 57% of the photovoltaic industry's market [1]. One major issue during directional solidification of silicon is the precipitation of foreign phase particles. These particles, mainly SiC and Si3N4, are precipitated from the dissolved crucible coating, which is made of silicon nitride, and the dissolution of carbon monoxide from the furnace atmosphere. Due to their hardness and size of several hundred micrometers, those particles can lead to severe problems during the wire sawing process for wafering the ingots. Additionally, SiC particles can act as a shunt, short circuiting the solar cell. Even if the particles are too small to disturb the wafering process, they can lead to a grit structure of silicon micro grains and serve as sources for dislocations. All of this lowers the yield of solar cells and reduces the performance of cells and modules. We studied the behaviour of SiC particle depots during float-zone growth under an oxide skin, and strong static magnetic fields. For high field strengths of 3T and above and an oxide layer on the sample surface, convection is sufficiently suppressed to create a diffusive like regime, with strongly dampened convection [2, 3]. To investigate the difference between atomically rough phase boundaries and facetted growth, samples with [100] and [111] orientation were processed.

  10. Human and Mouse Hematopoietic Stem Cells Are a Depot for Dormant Mycobacterium tuberculosis.

    Directory of Open Access Journals (Sweden)

    Julia Tornack

    Full Text Available An estimated third of the world's population is latently infected with Mycobacterium tuberculosis (Mtb, with no clinical signs of tuberculosis (TB, but lifelong risk of reactivation to active disease. The niches of persisting bacteria during latent TB infection remain unclear. We detect Mtb DNA in peripheral blood selectively in long-term repopulating pluripotent hematopoietic stem cells (LT-pHSCs as well as in mesenchymal stem cells from latently infected human donors. In mice infected with low numbers of Mtb, that do not develop active disease we, again, find LT-pHSCs selectively infected with Mtb. In human and mouse LT-pHSCs Mtb are stressed or dormant, non-replicating bacteria. Intratracheal injection of Mtb-infected human and mouse LT-pHSCs into immune-deficient mice resuscitates Mtb to replicating bacteria within the lung, accompanied by signs of active infection. We conclude that LT-pHSCs, together with MSCs of Mtb-infected humans and mice serve as a hitherto unappreciated quiescent cellular depot for Mtb during latent TB infection.

  11. Patient-reported outcomes with lanreotide Autogel/Depot for carcinoid syndrome: An international observational study.

    Science.gov (United States)

    Ruszniewski, Philippe; Valle, Juan W; Lombard-Bohas, Catherine; Cuthbertson, Daniel J; Perros, Petros; Holubec, Luboš; Delle Fave, Gianfranco; Smith, Denis; Niccoli, Patricia; Maisonobe, Pascal; Atlan, Philippe; Caplin, Martyn E

    2016-05-01

    Lanreotide Autogel/Depot effectively controls symptoms in patients with carcinoid syndrome associated with neuroendocrine tumours. Data on patient-reported outcomes are sparse. To evaluate the effect of lanreotide on patient-reported outcomes (PROs) with carcinoid syndrome. This was an international, open-label, observational study of adults with neuroendocrine tumours and history of diarrhoea, receiving lanreotide for >3 months for relief of carcinoid syndrome symptoms. The primary PRO measure was satisfaction with diarrhoea control. Secondary PRO measures included severity, change in symptoms and impact on daily life of diarrhoea; and patient satisfaction with flushing control. Of 273 patients enrolled, 76% were 'completely' or 'rather' satisfied with diarrhoea control; 79% reported improvement in diarrhoea with lanreotide. The proportion of patients with 'mild', 'minimal', or 'no diarrhoea' increased from 33% before treatment to 75% during treatment; 75% were unconcerned about the impact of diarrhoea on daily life. Satisfaction with flushing control amongst patients with significant flushing at treatment initiation was 73%. Lanreotide treatment was associated with improvements in symptoms as well as a range of PROs in patients with neuroendocrine tumours and carcinoid syndrome (ClinicalTrials.gov: NCT01234168). Copyright © 2016 The Authors. Published by Elsevier Ltd.. All rights reserved.

  12. Enhanced intelligent water drops algorithm for multi-depot vehicle routing problem.

    Science.gov (United States)

    Ezugwu, Absalom E; Akutsah, Francis; Olusanya, Micheal O; Adewumi, Aderemi O

    2018-01-01

    The intelligent water drop algorithm is a swarm-based metaheuristic algorithm, inspired by the characteristics of water drops in the river and the environmental changes resulting from the action of the flowing river. Since its appearance as an alternative stochastic optimization method, the algorithm has found applications in solving a wide range of combinatorial and functional optimization problems. This paper presents an improved intelligent water drop algorithm for solving multi-depot vehicle routing problems. A simulated annealing algorithm was introduced into the proposed algorithm as a local search metaheuristic to prevent the intelligent water drop algorithm from getting trapped into local minima and also improve its solution quality. In addition, some of the potential problematic issues associated with using simulated annealing that include high computational runtime and exponential calculation of the probability of acceptance criteria, are investigated. The exponential calculation of the probability of acceptance criteria for the simulated annealing based techniques is computationally expensive. Therefore, in order to maximize the performance of the intelligent water drop algorithm using simulated annealing, a better way of calculating the probability of acceptance criteria is considered. The performance of the proposed hybrid algorithm is evaluated by using 33 standard test problems, with the results obtained compared with the solutions offered by four well-known techniques from the subject literature. Experimental results and statistical tests show that the new method possesses outstanding performance in terms of solution quality and runtime consumed. In addition, the proposed algorithm is suitable for solving large-scale problems.

  13. RISK MANAGEMENT AND RISK COMMUNICATION IN MOZAMBIQUE: THE CASE OF ARMS AND AMMUNITION DEPOTS OF MALHAZINE

    Directory of Open Access Journals (Sweden)

    Luca Bussotti

    2017-12-01

    Full Text Available Risk management and risk communication affect everybody’s daily life. Local authorities have the duty to manage public structures, to inform civilians of the risks coming from these structures, to implement prophylaxis procedures. Military storage sites are fully included in this category. This article presents – through a qualitative methodology based on risk analysis – how risk management and communication in weapons and ammunition warehouses is managed in a “partially free” country, using as a case-study, the Malhazine depot in Mozambique, which resulted in more than 100 deaths. In 2007, an extraordinary accident related to the management of obsolete conventional weapons occurred at the Malazhine warehouse. In this circumstance, the Mozambican Government adopted a policy of classifying the information “highly confidential”. This policy aimed at obscuring facts and responsibilities by hiding the causes of such a huge tragedy. This article concludes with the consideration that a high level of confidentiality in treating issues of public interest, such as the one kept in regard to Malhazine, does not help public authorities to effectively manage and prevent similar risks from occurring again, with resulting negative impacts on local populations.

  14. Assessing Army Professional Forums Metrics for Effectiveness and Impact

    National Research Council Canada - National Science Library

    Cianciolo, Anna T; Heiden, Charles G; Prevou, Michael I

    2006-01-01

    ... meet the challenges brought on by Army transformation. Army professional forums (APFs), powered by advances in collaborative toolsets and multimedia presentation software, provide a means for leader self-development and professional growth...

  15. The Impact of Artillery Precision Munitions on Army Strategic Objectives

    National Research Council Canada - National Science Library

    Kays, Michael J

    2006-01-01

    ... the past. The Army Strategic Planning Guidance, 2005, describes why and how the Army must change. It outlines the nature of future threats, with particular emphasis on the asymmetrical threats of today...

  16. An Identification of Interpersonal Skills for Building Army Civilian Leaders

    National Research Council Canada - National Science Library

    Elliott, Kari A; Erickson, Michael D; Fowler, Edward T; Gieseking, John K; Weiss, Mary P

    2006-01-01

    ... by Army civilian leaders. Thirty-eight (38) Army civilian managers from four leadership levels completed questionnaires and participated in face-to-face interviews describing the important interpersonal skills that were necessary...

  17. Nanotechnology Laboratory Collaborates with Army to Develop Botulism Vaccine | FNLCR

    Science.gov (United States)

    The Nanotechnology Characterization Laboratory (NCL) is collaborating with the Army to develop a candidate vaccine against botulism. Under a collaboration agreement between the National Cancer Institute and the U.S. Army Medical Research Institute of

  18. 2007 Posture Statement, Army Reserve: An Operational Force

    National Research Council Canada - National Science Library

    Stultz, Jack C

    2007-01-01

    The 2007 Army Reserve Posture Statement describes how the Army Reserve continues to transform from a strategic reserve to an operational force, meeting today's challenges as it better prepares for future uncertainties...

  19. Role Of The Army In Modern Pakistan

    Directory of Open Access Journals (Sweden)

    Vladislav Viktorovich Vorobiev

    2014-01-01

    Full Text Available The article studies the political development of the country in the modern period. Special attention is paid to the position of the army and its role in the Pakistani society. The article explores in detail the processes of gradual distancing of the army from politics and strengthening of civil society institutions. It is the first time in the Pakistani history that the civilian government managed to complete its full five-year constitutional term. Meanwhile, the country has been advancing on the path to democracy even after the elections 2013: a new civilian government has been formed in Pakistan. As compared with the previous phases of the country's development, the status of the army has considerably changed, evolved from "guiding force" to "shadow" guarantee of democratic development. The process has been largely encouraged by popular among officers feeling of tiredness: many of them are not ready to take power into their own hands and committed to their strictly constitutional duties. Despite this recent positive trend, the army continues to enjoy great authority in the society, often brokers political crisis and helps civilian authorities in settling such pressing problems as, for example, fight against extremism. The military will exert influence on government unless civil authorities are able to resist the current challenges and settle the actual problems. The role of "power broker" fully serves the interests of the top army brass.

  20. ROLE OF THE ARMY IN MODERN PAKISTAN

    Directory of Open Access Journals (Sweden)

    Vladislav Viktorovich Vorobiev

    2014-01-01

    Full Text Available The article studies the political development of the country in the modern period. Special attention is paid to the position of the army and its role in the Pakistani society. The article explores in detail the processes of gradual distancing of the army from politics and strengthening of civil society institutions. It is the first time in the Pakistani history that the civilian government managed to complete its full five-year constitutional term. Meanwhile, the country has been advancing on the path to democracy even after the elections 2013: a new civilian government has been formed in Pakistan. As compared with the previous phases of the country's development, the status of the army has considerably changed, evolved from "guiding force" to "shadow" guarantee of democratic development. The process has been largely encouraged by popular among officers feeling of tiredness: many of them are not ready to take power into their own hands and committed to their strictly constitutional duties. Despite this recent positive trend, the army continues to enjoy great authority in the society, often brokers political crisis and helps civilian authorities in settling such pressing problems as, for example, fight against extremism. The military will exert influence on government unless civil authorities are able to resist the current challenges and settle the actual problems. The role of "power broker" fully serves the interests of the top army brass.

  1. Evaluation of the US Army fallout prediction model

    International Nuclear Information System (INIS)

    Pernick, A.; Levanon, I.

    1987-01-01

    The US Army fallout prediction method was evaluated against an advanced fallout prediction model--SIMFIC (Simplified Fallout Interpretive Code). The danger zone areas of the US Army method were found to be significantly greater (up to a factor of 8) than the areas of corresponding radiation hazard as predicted by SIMFIC. Nonetheless, because the US Army's method predicts danger zone lengths that are commonly shorter than the corresponding hot line distances of SIMFIC, the US Army's method is not reliably conservative

  2. Predictors of suicide and accident death in the Army Study to Assess Risk and Resilience in Servicemembers (Army STARRS): results from the Army Study to Assess Risk and Resilience in Servicemembers (Army STARRS).

    Science.gov (United States)

    Schoenbaum, Michael; Kessler, Ronald C; Gilman, Stephen E; Colpe, Lisa J; Heeringa, Steven G; Stein, Murray B; Ursano, Robert J; Cox, Kenneth L

    2014-05-01

    The Army Study to Assess Risk and Resilience in Servicemembers (Army STARRS) is a multicomponent study designed to generate actionable recommendations to reduce Army suicides and increase knowledge of risk and resilience factors for suicidality. To present data on prevalence, trends, and basic sociodemographic and Army experience correlates of suicides and accident deaths among active duty Regular Army soldiers between January 1, 2004, and December 31, 2009, and thereby establish a foundation for future Army STARRS investigations. Analysis of trends and predictors of suicide and accident deaths using Army and Department of Defense administrative data systems. Participants were all members of the US Regular Army serving at any time between 2004 and 2009. Death by suicide or accident during active Army service. The suicide rate rose between 2004 and 2009 among never deployed and currently and previously deployed Regular Army soldiers. The accident death rate fell sharply among currently deployed soldiers, remained constant among the previously deployed, and trended upward among the never deployed. Increased suicide risk was associated with being a man (or a woman during deployment), white race/ethnicity, junior enlisted rank, recent demotion, and current or previous deployment. Sociodemographic and Army experience predictors were generally similar for suicides and accident deaths. Time trends in these predictors and in the Army's increased use of accession waivers (which relaxed some qualifications for new soldiers) do not explain the rise in Army suicides. Predictors of Army suicides were largely similar to those reported elsewhere for civilians, although some predictors distinct to Army service emerged that deserve more in-depth analysis. The existence of a time trend in suicide risk among never-deployed soldiers argues indirectly against the view that exposure to combat-related trauma is the exclusive cause of the increase in Army suicides.

  3. 30 Brigade Combat Teams: Is the Army too Small

    Science.gov (United States)

    2016-12-01

    the cost of inflation (Belasco 2015). Figure 1 depicts the impact of the BCA on the Army. The dark blue line shows funding...ABSTRACT (maximum 200 words) The purpose of this thesis is to determine the impact of a contingency operation on Army dwell time. The Department of... impact of a contingency operation on Army dwell time. The Department of Defense (DOD) goal for the active Army is for every one year a unit

  4. Human Capital Analytics to Manage the Army Officer Population

    Science.gov (United States)

    2017-06-09

    HUMAN CAPITAL ANALYTICS TO MANAGE THE ARMY OFFICER POPULATION A thesis presented to the Faculty of the U.S. Army Command and...From - To) AUG 2016 – JUNE 2017 4. TITLE AND SUBTITLE Human Capital Analytics to Manage the Army Officer Population 5a. CONTRACT NUMBER 5b...Analytics to manage the Army’s officer population . Human Capital Analytics has reduced the uncertanty associated with civilian sector HR polices and

  5. The Army Budget: FY 00/01 President's Budget. Assistant Secretary of the Army for Financial Management and Comptroller

    National Research Council Canada - National Science Library

    1999-01-01

    ...) 697-6241, DSN 227- 6241. Its purpose is to provide the Army leadership, OSD and members of Congress and their staffs a reference to the Army's FY2000/2001 biennial Budget Request (President's Budget...

  6. U.S. Army Research Laboratory Annual Review 2011

    Science.gov (United States)

    2011-12-01

    Specialty Dr. Jan W. Andzelm ...................................... Multiscale Modeling of Macromolecules and Polymers Dr. Howard E. Brandt ...Gurganus brief Maj. Gen. Nick Justice on ARL’s new experimental technique using DIC during the 2010 Army Science Conference. U.S. Army Research Laboratory 2800 Powder Mill Road • Adelphi, MD 20783-1197 www.arl.army.mil

  7. Prime Power: Filling the Army’s Electric Power Gap

    Science.gov (United States)

    1989-01-01

    standards throughout the world. 3-5 The Army’s prime power requirements of necessity include frequency conversion equipment, transformers, and...ManuaL l01-10-1, pp. 1-43. 2 Electric Load Data Seven U.S. Army Bases, Office of the Chief of Engineers, Department of Army Contract No. DACA -73-68-C

  8. Climate Assessment for Army Enterprise Planning Fact Sheet

    Science.gov (United States)

    2017-11-30

    or private organizations . Outcomes of DOD SERDP program climate change investments are being leveraged and adapted to Army enterprise process...Software Estimating Resistance and Resilience of Military Lands Using Vegetation Indices Tech report Climate Change Vulnerability of Army...TITLE: Climate Assessment for Army Enterprise Planning SUBMITTING ORGANIZATION : ERDC STO START YEAR / END YEAR: FY14-FY17 1. NARRATIVE

  9. Drug abuse control and the Salvation Army.

    Science.gov (United States)

    Gauntlett, S L

    1991-01-01

    The Salvation Army has been involved in the control of drug abuse since it was founded over 120 years ago, when alcohol was the predominant concern. Today, alcohol is still the most commonly abused substance, but the Salvation Army is increasingly tackling other forms of substance abuse as well. High priority is given to prevention of all levels and by all means through a network of over 200 specialized rehabilitation centres throughout the world, in addition to programmes within hostels for the homeless, where there is a high proportion of alcohol and other substance abusers. The Salvation Army endeavours to help drug-dependent persons to abstain from using drugs and achieve a healthy and happy life. It is of the view that, as drug dependence is usually a manifestation of deeper needs, the spiritual component is vital in dealing with drug abuse of all types.

  10. Fatty acid profiles and iodine value correlations between 4 carcass fat depots from pigs fed varied combinations of ractopamine and energy.

    Science.gov (United States)

    Wiegand, B R; Hinson, R B; Ritter, M J; Carr, S N; Allee, G L

    2011-11-01

    A total of 54 finishing barrows (initial BW = 99.8 ± 5.1 kg; PIC C22 × 337) reared in individual pens were allotted to 1 of 6 dietary treatments in a 2 × 3 factorial arrangement of treatments with 2 levels of ractopamine (0 and 7.4 mg/kg) and 3 levels of dietary energy (high: 3,537, medium: 3,369, and low: 3,317 kcal/kg of ME) to determine the effects of feeding ractopamine and various dietary energy levels on the fatty acid profile of 4 carcass fat depots (jowl, belly, subcutaneous loin, and intramuscular) and the predictive relationships of calculated iodine value (IV) between these 4 fat depots. Carcasses were sampled for fat tissues at the anterior tip of the jowl, posterior to the sternum on the belly edge, three-quarters the distance around the LM (subcutaneous fat; SC), and within the LM (intramuscular fat; IMF). Feeding ractopamine diets reduced (P ractopamine diets increased (P ractopamine diets shifted the fatty acid profile from SFA to MUFA in the SC depot. Feeding ractopamine diets did not change belly fat profiles, thus avoiding the potential negative effect of softening belly fat, which is detrimental to processing value. The IV of one fat depot may not be a good indication of IV of other fat depots because of weak correlation coefficients and the apparent influence of dietary treatment.

  11. Army Energy and Water Reporting System Assessment

    Energy Technology Data Exchange (ETDEWEB)

    Deprez, Peggy C.; Giardinelli, Michael J.; Burke, John S.; Connell, Linda M.

    2011-09-01

    There are many areas of desired improvement for the Army Energy and Water Reporting System. The purpose of system is to serve as a data repository for collecting information from energy managers, which is then compiled into an annual energy report. This document summarizes reported shortcomings of the system and provides several alternative approaches for improving application usability and adding functionality. The U.S. Army has been using Army Energy and Water Reporting System (AEWRS) for many years to collect and compile energy data from installations for facilitating compliance with Federal and Department of Defense energy management program reporting requirements. In this analysis, staff from Pacific Northwest National Laboratory found that substantial opportunities exist to expand AEWRS functions to better assist the Army to effectively manage energy programs. Army leadership must decide if it wants to invest in expanding AEWRS capabilities as a web-based, enterprise-wide tool for improving the Army Energy and Water Management Program or simply maintaining a bottom-up reporting tool. This report looks at both improving system functionality from an operational perspective and increasing user-friendliness, but also as a tool for potential improvements to increase program effectiveness. The authors of this report recommend focusing on making the system easier for energy managers to input accurate data as the top priority for improving AEWRS. The next major focus of improvement would be improved reporting. The AEWRS user interface is dated and not user friendly, and a new system is recommended. While there are relatively minor improvements that could be made to the existing system to make it easier to use, significant improvements will be achieved with a user-friendly interface, new architecture, and a design that permits scalability and reliability. An expanded data set would naturally have need of additional requirements gathering and a focus on integrating

  12. The use of depot-medroxyprogesterone acetate in contraception and its potential impact on skeletal health.

    Science.gov (United States)

    Guilbert, Edith R; Brown, Jacques P; Kaunitz, Andrew M; Wagner, Marie-Soleil; Bérubé, Jocelyn; Charbonneau, Louise; Francoeur, Diane; Gilbert, Andrée; Gilbert, François; Roy, Geneviève; Senikas, Vyta; Jacob, Robert; Morin, Réal

    2009-03-01

    In the fall of 2007, the controversy about the contraceptive use of depot-medroxyprogesterone acetate (DMPA) and its potential impact on skeletal health reached the media in the province of Quebec, Canada, thereby becoming a matter of concern for the lay public and physicians. In order to discuss this subject openly, the National Institute of Public Health of Quebec (INSPQ) organized a scientific meeting on February 15, 2008, with targeted physicians delegated by their medical associations in the fields of general practice, obstetrics and gynaecology, rheumatology, orthopaedic surgery, physiatry and endocrinology. Participants reviewed the scientific literature using the study classification method according to the level of evidence, reviewed published guidelines of medical societies and organizations on the subject and reached a consensus position. This manuscript presents a review of the literature and describes the consensus position of the targeted medical associations. The consensus position adopted by all the targeted medical associations determined that DMPA was a cost-effective contraceptive option that must be considered in the light of the clinical situation and preference of each woman. Candidates for injectable contraception should be informed that the use of DMPA is associated with a slight decrease in bone mineral density (BMD), which is largely, if not completely, reversible. There should not be an absolute limit to the length of time that the DMPA contraceptive is used, regardless of the woman's age. Monitoring BMD is not recommended among users of DMPA for contraceptive purposes. Finally, the consensus statement declared that, although supplements of calcium and vitamin D are beneficial for skeletal health for women in general, such supplementation should not be recommended solely based on a woman's use of DMPA. Given the scientific evidences, DMPA use remains a valid contraceptive option for women. Its potential impact on BMD must be balanced

  13. The Lipid-Droplet Proteome Reveals that Droplets Are a Protein-Storage Depot

    Energy Technology Data Exchange (ETDEWEB)

    Cermelli, Silvia; Guo, Yi; Gross, Steven P.; Welte, Michael

    2006-09-19

    Lipid droplets are ubiquitous organelles that are among the basic building blocks of eukaryotic cells. Despite central roles for cholesterol homeostasis and lipid metabolism, their function and protein composition are poorly understood. Results: We purified lipid droplets from Drosophila embryos and analyzed the associated proteins by capillary LC-MS-MS. Important functional groups include enzymes involved in lipid metabolism, signaling molecules, and proteins related to membrane trafficking. Unexpectedly, histones H2A, H2Av, and H2B were present. Using biochemistry, genetics, real-time imaging, and cell biology, we confirm that roughly 50% of certain embryonic histones are physically attached to lipid droplets, a localization conserved in other fly species. Histone association with droplets starts during oogenesis and is prominent in early embryos, but it is undetectable in later stages or in cultured cells. Histones on droplets are not irreversibly trapped; quantitation of droplet histone levels and transplantation experiments suggest that histones are transferred from droplets to nuclei as development proceeds. When this maternal store of histones is unavailable because lipid droplets are mislocalized, zygotic histone production starts prematurely. Conclusions: Because we uncover a striking proteomic similarity of Drosophila droplets to mammalian lipid droplets, Drosophila likely provides a good model for understanding droplet function in general. Our analysis also reveals a new function for these organelles; the massive nature of histone association with droplets and its developmental time-course suggest that droplets sequester maternally provided proteins until they are needed. We propose that lipid droplets can serve as transient storage depots for proteins that lack appropriate binding partners in the cell. Such sequestration may provide a general cellular strategy for handling excess proteins.

  14. Adipose tissue endocannabinoid system gene expression: depot differences and effects of diet and exercise

    Directory of Open Access Journals (Sweden)

    Yang Rongze

    2011-10-01

    Full Text Available Abstract Background Alterations of endocannabinoid system in adipose tissue play an important role in lipid regulation and metabolic dysfunction associated with obesity. The purpose of this study was to determine whether gene expression levels of cannabinoid type 1 receptor (CB1 and fatty acid amide hydrolase (FAAH are different in subcutaneous abdominal and gluteal adipose tissue, and whether hypocaloric diet and aerobic exercise influence subcutaneous adipose tissue CB1 and FAAH gene expression in obese women. Methods Thirty overweight or obese, middle-aged women (BMI = 34.3 ± 0.8 kg/m2, age = 59 ± 1 years underwent one of three 20-week weight loss interventions: caloric restriction only (CR, N = 9, caloric restriction plus moderate-intensity aerobic exercise (CRM, 45-50% HRR, N = 13, or caloric restriction plus vigorous-intensity aerobic exercise (CRV, 70-75% HRR, N = 8. Subcutaneous abdominal and gluteal adipose tissue samples were collected before and after the interventions to measure CB1 and FAAH gene expression. Results At baseline, FAAH gene expression was higher in abdominal, compared to gluteal adipose tissue (2.08 ± 0.11 vs. 1.78 ± 0.10, expressed as target gene/β-actin mRNA ratio × 10-3, P Conclusions There are depot differences in subcutaneous adipose tissue endocannabinoid system gene expression in obese individuals. Aerobic exercise training may preferentially modulate abdominal adipose tissue endocannabinoid-related gene expression during dietary weight loss. Trial Registration ClinicalTrials.gov: NCT00664729.

  15. Depot-specific differences in fat mass expansion in WT and ob/ob mice.

    Science.gov (United States)

    Wang, Xinxia; Yu, Caihua; Feng, Jie; Chen, Jin; Jiang, Qin; Kuang, Shihuan; Wang, Yizhen

    2017-07-11

    The study was designed to investigate the cellular mechanisms underlying the differential fat expansion in different fat depots in wild type (WT) and ob/ob (OB) mice. At 6 weeks old, no differences in fat mass were found between SAT and VAT in WT mice, while O-SAT showed significantly higher weight than that of O-VAT. The average adipocyte size of SAT (~ 4133.47 μm2) was smaller than that of VAT (~ 7438.91 μm2) in OB mice. O-SAT preadipocytes gained higher triglyceride contents and higher levels of PPARγ and C/EBPα than did O-VAT preadipocytes upon in vitro differentiation. W-SAT and W-VAT displayed no significant differences in fatty acid uptake, while 1.36 fold significantly higher fatty acid uptake was found in O-SAT compared to O-VAT. Approximately 52% of the radioactivity recovered in cellular lipids was found in TAG in O-SAT, which was significantly higher than the other three adipocyte types. Significantly more radiolabelled oleic acid was β-oxidized to CO2 in adipocytes from O-VAT than that from O-SAT. ATP production was significantly lower in W-SAT compared with W-VAT, whereas no significantly ATP level was observed between O-SAT and O-VAT. Expression of UCP-1 in SAT from either WT or OB mice was significantly higher than the counterpart of VAT, which demonstrated higher uncoupled respiration and lower oxidative phosphorylation in SAT. Together, a combined increase in adipogenesis and FA uptake, and decreases in β-oxidation and ATP production, contributed to greater expansion of SAT compared to VAT in obese mice.

  16. Depot-Specific Changes in Fat Metabolism with Aging in a Type 2 Diabetic Animal Model.

    Science.gov (United States)

    Park, Se Eun; Park, Cheol-Young; Choi, Jung Mook; Chang, Eugene; Rhee, Eun-Jung; Lee, Won-Young; Oh, Ki Won; Park, Sung Woo; Kang, Eun Seok; Lee, Hyun Chul; Cha, Bong Soo

    2016-01-01

    Visceral fat accretion is a hallmark of aging and is associated with aging-induced metabolic dysfunction. PPARγ agonist was reported to improve insulin sensitivity by redistributing fat from visceral fat to subcutaneous fat. The purpose of this study was to investigate the underlying mechanisms by which aging affects adipose tissue remodeling in a type 2 diabetic animal model and through which PPARγ activation modulates aging-related fat tissue distribution. At the ages of 21, 31 and 43 weeks, OLETF rats as an animal model of type 2 diabetes were evaluated for aging-related effects on adipose tissue metabolism in subcutaneous and visceral fat depots. During aging, the ratio of visceral fat weight to subcutaneous fat weight (V/S ratio) increased. Aging significantly increased the mRNA expression of genes involved in lipogenesis such as lipoprotein lipase, fatty acid binding protein aP2, lipin 1, and diacylglycerol acyltransferase 1, which were more prominent in visceral fat than subcutaneous fat. The mRNA expression of adipose triglyceride lipase, which is involved in basal lipolysis and fatty acid recycling, was also increased, more in visceral fat compared to subcutaneous fat during aging. The mRNA levels of the genes associated with lipid oxidation were increased, whereas the mRNA levels of genes associated with energy expenditure showed no significant change during aging. PPARγ agonist treatment in OLETF rats resulted in fat redistribution with a decreasing V/S ratio and improved glucose intolerance. The genes involved in lipogenesis decreased in visceral fat of the PPARγ agonist-treated rats. During aging, fat distribution was changed by stimulating lipid uptake and esterification in visceral fat rather than subcutaneous fat, and by altering the lipid oxidation.

  17. US Army primary radiation standards complex

    International Nuclear Information System (INIS)

    Rogers, S.C.

    1993-01-01

    This paper describes the U.S. Army Primary Radiation Standards Complex (PRSC) to be constructed at Redstone Arsenal, Alabama. The missions of the organizations to be located in the PRSC are described. The health physics review of the facility design is discussed. The radiation sources to be available in the PRSC and the resulting measurement capabilities of the Army Primary Standards Laboratory Nucleonics section are specified. Influence of the National Voluntary Laboratory Accrediation Program (NVLAP) accreditation criteria on facility design and source selection is illustrated

  18. A comparative study of cross sectional anatomy and computer tomography of perirenal fat depots in New Zealand White rabbits

    International Nuclear Information System (INIS)

    Yonkova, P.; Dimitrov, R.; Toneva, J.; Zapryanova, D.

    2010-01-01

    CT is a contemporary non-invasive imaging technique that gains an increasing importance for in vivo investigations of subcutaneous and visceral fat. The purpose of this investigation was to describe the topography and anatomy imaging features of perirenal fat depots at the level of both kidneys in clinically healthy New Zealand White rabbits that attained slaughter weight. The CT consecutive transverse scans from the last thoracic to the fifth lumbar vertebrae showed that in rabbits, perirenal fat appeared as a homogeneous hypodense structure at the background of denser shadows of lumbar and abdominal muscles, kidneys and abdominal organs. Perirenal fat depot exhibited a soft tissue density with average attenuation of −120.97±4.73 HU. On CT scans, the largest dimensions of the perirenal fat depot were 1.3±0.01 cm at the level of the right kidneys cranial pole; 1.96 cm in the plane where the right renal hilus was visualized; 1.66±0.08 cm at the level of the right kidneys caudal pole; 1.10±0.18 cm in the plane where the left renal hilus was visualized and 1.06±0.15 cm at the level of the left kidneys caudal pole. No subcutaneous fat deposits in the abdominal area were seen. Results obtained in the present study could be used as basic information for various anatomy investigations of rabbits as well as experimental designs for study of obesity in animals and humans. (author)

  19. Factors predicting health behaviors among Army Reserve, active duty Army, and civilian hospital employees.

    Science.gov (United States)

    Wynd, Christine A; Ryan-Wenger, Nancy A

    2004-12-01

    This study identified health-risk and health-promoting behaviors in military and civilian personnel employed in hospitals. Intrinsic self-motivation and extrinsic organizational workplace factors were examined as predictors of health behaviors. Because reservists represent a blend of military and civilian lifestyles, descriptive analyses focused on comparing Army Reserve personnel (n = 199) with active duty Army (n = 218) and civilian employees (n = 193), for a total sample of 610. Self-motivation and social support were significant factors contributing to the adoption of health-promoting behaviors; however, organizational workplace cultures were inconsistent predictors of health among the three groups. Only the active Army subgroup identified a hierarchical culture as having an influence on health promotion, possibly because of the Army's mandatory physical fitness and weight control standards. Social support and self-motivation are essential to promoting health among employees, thus hospital commanders and chief executive officers should encourage strategies that enhance and reward these behaviors.

  20. Army Business Transformation: The Utility of Using Corporate Business Models within the Institutional Army

    National Research Council Canada - National Science Library

    Bailer, Jr., John J

    2007-01-01

    .... This study finds that working corporate models, such as Lean Six Sigma (LSS), are available which are already enabling the transformation of a very specific aspect within the institutional Army...

  1. Simulation and Animation of the Cherry Point, North Carolina Naval Aviation Depot Proposed Engine Blade and Vane Rework Facility

    Science.gov (United States)

    1988-11-10

    mg ’ ilel Ex::;erirrent f ile is given a ",.E" e>:.-Aension. Once...selecting option KE...’:> > , or <F.>. Ecape returns the user t.,-, the Main Menu. CHERRY FOINT NAVAL AVIATION DEPOT ANIMATION MENU GD TO CINEMA MENU...t. 1~~~~~C ’.K T ’ FOE(7D;- OPT I ON?:" : MH=;:8 1 ’ jK’rgs. 1 LY’ 1 7)K: MG RE E’’ 1 71-16 MAs $ SF0R D" 1 ,(𔄁t) MtS’ $FE MAGENTA": * 47:,-; MAIt

  2. A multi-objective Pareto ant colony algorithm for the Multi-Depot Vehicle Routing problem with Backhauls

    Directory of Open Access Journals (Sweden)

    Jhon Jairo Santa Chávez

    2016-01-01

    Full Text Available This paper presents a multiobjective ant colony algorithm for the Multi-Depot Vehicle Routing Problem with Backhauls (MDVRPB where three objectives of traveled distance, traveling times and total consumption of energy are minimized. An ant colony algorithm is proposed to solve the MDVRPB. The solution scheme allows one to find a set of ordered solutions in Pareto fronts by considering the concept of dominance. The effectiveness of the proposed approach is examined by considering a set of instances adapted from the literature. The computational results show high quality results within short computing times.

  3. Feasibility Study of Economics and Performance of Wind Turbine Generators at the Newport Indiana Chemical Depot Site

    Energy Technology Data Exchange (ETDEWEB)

    Roberts, Joseph Owen [National Renewable Energy Lab. (NREL), Golden, CO (United States); Mosey, Gail [National Renewable Energy Lab. (NREL), Golden, CO (United States)

    2013-11-01

    The U.S. Environmental Protection Agency (EPA), in accordance with the RE-Powering America's Land initiative, selected the Newport Indiana Chemical Depot site in Newport, Indiana, for a feasibility study of renewable energy production. The National Renewable Energy Laboratory (NREL) was contacted to provide technical assistance for this project. The purpose of this report is to assess the sitefor possible wind turbine electrical generator installation and estimate the cost, performance, and site impacts of different wind energy options. In addition, the report recommends financing options that could assist in the implementation of a wind system at the site.

  4. External Collaboration in Army Science and Technology: The Army’s Research Alliances

    Science.gov (United States)

    2013-09-01

    to execute and link neuroscience based research from multiple levels to produce advances in fundamental science and technology, demonstrate and...network science, and cognitive neuroscience .”19 The ICT, first funded in 1999, was first established “with a multi-year contract from the U.S. Army...frontiers of knowledge. In 2011 the Army Research Office awarded eight MURIs. The topics included quantum science, biologics, nanotechnology and atomic

  5. Army Strong: Equipped, Trained and Ready. Final Report of the 2010 Army Acquisition Review

    Science.gov (United States)

    2011-01-01

    Army, Executive Officer John R. Cason , Senior Acquisition Policy Advisor Hye Sun Miller, Executive Assistant The panel also received support...Panel Executive Officer • John Cason , Acquisition Policy Advisor, ASA(ALT) • Hye Sun Miller, Executive Assistant The Panel also received support...34Service Contracting," Office of the Assistant Secretary of the Army, Acquisition, Logistics and Technology, email to John R. Cason , 26 October 2010

  6. Evaluating Mobile Device Ownership and Usage in the U.S. Army: Implications for Army Training

    Science.gov (United States)

    2014-07-01

    Mercado University of Central Florida Randall D. Spain U.S. Army Research Institute July 2014 United States Army...NUMBER 633007 6. AUTHOR(S) Joseph E. Mercado ; Randall D. Spain 5c. PROJECT NUMBER A792 5d. TASK NUMBER 5e...13. SUPPLEMENTARY NOTES Subject Matter POC and Subject Matter Expert: Joseph E. Mercado 14. ABSTRACT (Maximum 200 words): As the U.S

  7. Predictors of Suicide and Accident Death in the Army Study to Assess Risk and Resilience in Servicemembers (Army STARRS)

    Science.gov (United States)

    Schoenbaum, Michael; Kessler, Ronald C.; Gilman, Stephen E.; Colpe, Lisa J.; Heeringa, Steven G.; Stein, Murray B.; Ursano, Robert J.; Cox, Kenneth L.

    2014-01-01

    IMPORTANCE The Army Study to Assess Risk and Resilience in Servicemembers (Army STARRS) is a multicomponent study designed to generate actionable recommendations to reduce Army suicides and increase knowledge of risk and resilience factors for suicidality. OBJECTIVES To present data on prevalence, trends, and basic sociodemographic and Army experience correlates of suicides and accident deaths among active duty Regular Army soldiers between January 1, 2004, and December 31, 2009, and thereby establish a foundation for future Army STARRS investigations. DESIGN, SETTING, AND PARTICIPANTS Analysis of trends and predictors of suicide and accident deaths using Army and Department of Defense administrative data systems. Participants were all members of the US Regular Army serving at any time between 2004 and 2009. MAIN OUTCOMES AND MEASURES Death by suicide or accident during active Army service. RESULTS The suicide rate rose between 2004 and 2009 among never deployed and currently and previously deployed Regular Army soldiers. The accident death rate fell sharply among currently deployed soldiers, remained constant among the previously deployed, and trended upward among the never deployed. Increased suicide risk was associated with being a man (or a woman during deployment), white race/ethnicity, junior enlisted rank, recent demotion, and current or previous deployment. Sociodemographic and Army experience predictors were generally similar for suicides and accident deaths. Time trends in these predictors and in the Army’s increased use of accession waivers (which relaxed some qualifications for new soldiers) do not explain the rise in Army suicides. CONCLUSIONS AND RELEVANCE Predictors of Army suicides were largely similar to those reported elsewhere for civilians, although some predictors distinct to Army service emerged that deserve more in-depth analysis. The existence of a time trend in suicide risk among never-deployed soldiers argues indirectly against the view

  8. Design of the Army Study to Assess Risk and Resilience in Servicemembers (Army STARRS).

    Science.gov (United States)

    Kessler, Ronald C; Colpe, Lisa J; Fullerton, Carol S; Gebler, Nancy; Naifeh, James A; Nock, Matthew K; Sampson, Nancy A; Schoenbaum, Michael; Zaslavsky, Alan M; Stein, Murray B; Ursano, Robert J; Heeringa, Steven G

    2013-12-01

    The Army Study to Assess Risk and Resilience in Servicemembers (Army STARRS) is a multi-component epidemiological and neurobiological study designed to generate actionable evidence-based recommendations to reduce US Army suicides and increase basic knowledge about the determinants of suicidality. This report presents an overview of the designs of the six components of the Army STARRS. These include: an integrated analysis of the Historical Administrative Data Study (HADS) designed to provide data on significant administrative predictors of suicides among the more than 1.6 million soldiers on active duty in 2004-2009; retrospective case-control studies of suicide attempts and fatalities; separate large-scale cross-sectional studies of new soldiers (i.e. those just beginning Basic Combat Training [BCT], who completed self-administered questionnaires [SAQs] and neurocognitive tests and provided blood samples) and soldiers exclusive of those in BCT (who completed SAQs); a pre-post deployment study of soldiers in three Brigade Combat Teams about to deploy to Afghanistan (who completed SAQs and provided blood samples) followed multiple times after returning from deployment; and a platform for following up Army STARRS participants who have returned to civilian life. Department of Defense/Army administrative data records are linked with SAQ data to examine prospective associations between self-reports and subsequent suicidality. The presentation closes with a discussion of the methodological advantages of cross-component coordination. Copyright © 2013 John Wiley & Sons, Ltd.

  9. Field procedures in the Army Study to Assess Risk and Resilience in Servicemembers (Army STARRS).

    Science.gov (United States)

    Heeringa, Steven G; Gebler, Nancy; Colpe, Lisa J; Fullerton, Carol S; Hwang, Irving; Kessler, Ronald C; Naifeh, James A; Nock, Matthew K; Sampson, Nancy A; Schoenbaum, Michael; Zaslavsky, Alan M; Stein, Murray B; Ursano, Robert J

    2013-12-01

    The Army Study to Assess Risk and Resilience in Servicemembers (Army STARRS) is a multi-component epidemiological and neurobiological study of unprecedented size and complexity designed to generate actionable evidence-based recommendations to reduce US Army suicides and increase basic knowledge about determinants of suicidality by carrying out coordinated component studies. A number of major logistical challenges were faced in implementing these studies. The current report presents an overview of the approaches taken to meet these challenges, with a special focus on the field procedures used to implement the component studies. As detailed in the paper, these challenges were addressed at the onset of the initiative by establishing an Executive Committee, a Data Coordination Center (the Survey Research Center [SRC] at the University of Michigan), and study-specific design and analysis teams that worked with staff on instrumentation and field procedures. SRC staff, in turn, worked with the Office of the Deputy Under Secretary of the Army (ODUSA) and local Army Points of Contact (POCs) to address logistical issues and facilitate data collection. These structures, coupled with careful fieldworker training, supervision, and piloting, contributed to the major Army STARRS data collection efforts having higher response rates than previous large-scale studies of comparable military samples. Copyright © 2013 John Wiley & Sons, Ltd.

  10. Transforming the Army with Mission Command

    Science.gov (United States)

    2015-06-12

    inevitable change that is the dominant factor in society today. No sensible decision can be made any longer without taking into account not only the...commitment that are hallmarks of an Army Professional. Build the comprehensive physical, mental, emotional , and spiritual resiliency of our Soldiers

  11. The Army Wants More Family Physicians.

    Science.gov (United States)

    1988-03-23

    Pfieffer , U.S. Office of the Surgeon General of the Army, Washington D.C., 8 February 1988. 3. American Medical Association, The Directory of...unit surgeon did not prepare him for the myriad skin deseases, diarrheal syndromes , fevers, and other problems. Despite the excellent efforts in the

  12. The all Volunteer Army: Impact on Readines

    Science.gov (United States)

    1979-06-08

    directing traffic at busy installations to flying UH-l helicopters. Of the 377 enlisted military occupational specialties in the Army today, about... childish and unimportant. Military sanitation reasons for shorter hair are the normal responses to the question of longer hair. Rarely, if ever, are the

  13. The Army Ethic-Inchoate but Sufficient

    Science.gov (United States)

    2015-06-12

    Army really cares why a Soldier does the right thing and whether the decision came from compulsion or fear or by accident. An aspirational ethic must...its approach, Soldiers will respond negatively. It takes time to introduce, train, and see the profession buy in to something new, especially an

  14. The Army's Role in Nation Building

    National Research Council Canada - National Science Library

    Edmonds, Mark L

    2009-01-01

    ... should be and how to execute this task. The tasks associated with nation building are part of the Army's core competencies under the auspices of 'Stability Operations', and are now cited in doctrine in the recently published Field Manual 3-07...

  15. Reuse of Waste Oil at Army Installations.

    Science.gov (United States)

    1982-09-01

    Thousands of gallons ot used crankcase oil are The Toxic Substance Control Act (PL 94-4,0) bulned each year ii Army boilers. Before an instal- regulates...ATTN: Chief. SwGAS-L ATTN: ATZLCA-SA ATTN: Chief. SWGCO-M Los Angeles 90053 Ft. Lee, VA 23801 ATTN: Chief. SPLED-E ATTN: DRXMC-U (2) San Francisco

  16. Public Reporting and a More Sustainable Army

    Science.gov (United States)

    2009-04-01

    CorporateRegister.com maintains on its website a global directory of corporate social responsibility (CSR), sustainability, and environmental reports. The...CSR corporate social responsibility CW Civil Works CWA Clean Water Act DA Department of the Army DLA Defense Logistics Agency DoD Department of

  17. Comparative Transcriptome Analysis of Adipose Tissues Reveals that ECM-Receptor Interaction Is Involved in the Depot-Specific Adipogenesis in Cattle.

    Directory of Open Access Journals (Sweden)

    Hyun-Jeong Lee

    Full Text Available Adipocytes mainly function as energy storage and endocrine cells. Adipose tissues showed the biological and genetic difference based on their depots. The difference of adipocytes between depots might be influenced by the inherent genetic programing for adipogenesis. We used RNA-seq technique to investigate the transcriptomes in 3 adipose tissues of omental (O, subcutaneous (S and intramuscular (I fats in cattle. Sequence reads were obtained from Illumina HiSeq2000 and mapped to the bovine genome using Tophat2. Differentially expressed genes (DEG between adipose tissues were detected by EdgeR. We identified 5797, 2156, and 5455 DEGs in the comparison between OI, OS, and IS respectively and also found 5657 DEGs in the comparison between the intramuscular and the combined omental and subcutaneous fats (C (FDR<0.01. Depot specifically up- and down- regulated DEGs were 853 in S, 48 in I, and 979 in O. The numbers of DEGs and functional annotation studies suggested that I had the different genetic profile compared to other two adipose tissues. In I, DEGs involved in the developmental process (eg. EGR2, FAS, and KLF7 were up-regulated and those in the immune system process were down-regulated. Many DEGs from the adipose tissues were enriched in the various GO terms of developmental process and KEGG pathway analysis showed that the ECM-receptor interaction was one of commonly enriched pathways in all of the 3 adipose tissues and also functioned as a sub-pathway of other enriched pathways. However, genes involved in the ECM-receptor interaction were differentially regulated depending on the depots. Collagens, main ECM constituents, were significantly up-regulated in S and integrins, transmembrane receptors, were up-regulated in I. Different laminins were up-regulated in the different depots. This comparative transcriptome analysis of three adipose tissues suggested that the interactions between ECM components and transmembrane receptors of fat cells

  18. Cost-Effectiveness of Financial Incentives to Promote Adherence to Depot Antipsychotic Medication: Economic Evaluation of a Cluster-Randomised Controlled Trial.

    Directory of Open Access Journals (Sweden)

    Catherine Henderson

    Full Text Available Offering a modest financial incentive to people with psychosis can promote adherence to depot antipsychotic medication, but the cost-effectiveness of this approach has not been examined.Economic evaluation within a pragmatic cluster-randomised controlled trial. 141 patients under the care of 73 teams (clusters were randomised to intervention or control; 138 patients with diagnoses of schizophrenia, schizo-affective disorder or bipolar disorder participated. Intervention participants received £15 per depot injection over 12 months, additional to usual acute, mental and community primary health services. The control group received usual health services. Main outcome measures: incremental cost per 20% increase in adherence to depot antipsychotic medication; incremental cost of 'good' adherence (defined as taking at least 95% of the prescribed number of depot medications over the intervention period.Economic and outcome data for baseline and 12-month follow-up were available for 117 participants. The adjusted difference in adherence between groups was 12.2% (73.4% control vs. 85.6% intervention; the adjusted costs difference was £598 (95% CI -£4,533, £5,730. The extra cost per patient to increase adherence to depot medications by 20% was £982 (95% CI -£8,020, £14,000. The extra cost per patient of achieving 'good' adherence was £2,950 (CI -£19,400, £27,800. Probability of cost-effectiveness exceeded 97.5% at willingness-to-pay values of £14,000 for a 20% increase in adherence and £27,800 for good adherence.Offering a modest financial incentive to people with psychosis is cost-effective in promoting adherence to depot antipsychotic medication. Direct healthcare costs (including costs of the financial incentive are unlikely to be increased by this intervention.ISRCTN.com 77769281.

  19. United States Army Annual Financial Statement FY00. The Army in Transformation Responsive to the Needs of the Nation

    Science.gov (United States)

    2000-01-01

    United States Army Annual Financial Statement “The Army in Transformation—Responsive to the Needs of the Nation” The picture of the digitized soldier...mailing the postage paid comment card enclosed at the back of this report. “The Army in Transformation —Responsive to the Needs of the Nation” “The...Army in Transformation —Responsive to the Needs of the Nation” “The Army in Transformation—Responsive to the Needs of the Nation” Table of Contents FY00

  20. Vanadate impedes adipogenesis in mesenchymal stem cells derived from different depots within bone.

    Directory of Open Access Journals (Sweden)

    Frans Alexander Jacobs

    2016-08-01

    Full Text Available Glucocorticoid induced osteoporosis (GIO is associated with an increase in bone marrow adiposity which skews the differentiation of mesenchymal stem cell (MSC progenitors away from osteoblastogenesis and towards adipogenesis. We have previously found that vanadate, a non-specific protein tyrosine phosphatase inhibitor, prevents GIO in rats, but it was unclear whether vanadate directly influenced adipogenesis in bone-derived MSCs. For the present study, we investigated the effect of vanadate on adipogenesis in primary rat MSCs derived from bone marrow (bmMSCs and from the proximal end of the femur (pfMSCs. By passage 3 after isolation, both cell populations expressed the MSC cell surface markers CD90 and CD106, but not the haematopoietic marker CD45. However, although variable, expression of the fibroblast marker CD26 was higher in pfMSCs than in bmMSCs. Differentiation studies using osteogenic and adipogenic induction media (OM and AM, respectively demonstrated that pfMSCs rapidly accumulated lipid droplets within 1 week of exposure to AM, while bmMSCs isolated from the same femur only formed lipid droplets after 3 weeks of AM treatment. Conversely, pfMSCs exposed to OM produced mineralized extracellular matrix (ECM after 3 weeks, compared to 1 week for OM-treated bmMSCs. Vanadate (10 µM added to AM resulted in a significant reduction in AM-induced intracellular lipid accumulation and expression of adipogenic gene markers (PPARγ2, aP2, adipsin in both pfMSCs and bmMSCs. Pharmacological concentrations of glucocorticoids (1 µM alone did not induce lipid accumulation in either bmMSCs or pfMSCs, but resulted in significant cell death in pfMSCs. Our findings demonstrate the existence of at least two fundamentally different MSC depots within the femur, and highlights the presence of MSCs capable of rapid adipogenesis within the proximal femur, an area prone to osteoporotic fractures. In addition, our results suggest that the increased bone marrow

  1. Formulation optimization of long-acting depot injection of aripiprazole by using D-optimal mixture design.

    Science.gov (United States)

    Nahata, Tushar; Saini, T R

    2009-01-01

    Non-adherence to medication specifications is a major cause for poor outcomes in the therapy of schizophrenia. In situ implantable preparation of aripiprazole, an atypical antipsychotic drug, was intended with the aim to improve the patient compliance and to offer an effective antipsychotic drug therapy. D-optimal mixture design was employed to design and optimize long-acting depot injection of aripiprazole using polylactide-co-glycolide (PLGA) 50:50, 75:25, 85:15, and cholesterol as release rate-retarding material. Desirability technique was used for the optimization of formulation. Predicted optimized formulation was experimentally validated, and it was found that the developed formulation releases the drug for a 14-day time period. The optimized formulation showed that the cholesterol-containing formulation exhibits a better drug release profile. The pharmacokinetic studies confirmed that the developed cholesterol-based depot formulation was capable of releasing the drug for a time period of more than 14 days. The implant formulation was sterilized by gamma radiation and ethylene oxide sterilization method. The D-optimal mixture design was proved to be an efficient technique for the formulation optimization.

  2. Where does hydrolysis of nandrolone decanoate occur in the human body after release from an oil depot?

    Science.gov (United States)

    Kalicharan, R W; Bout, M R; Oussoren, C; Vromans, H

    2016-12-30

    Long-term therapy of nandrolone (N) is recommended to increase mineral density and muscle strength. Using a parenteral sustained release drug formulation with nandrolone decanoate (ND), therapeutic N levels can be achieved and maintained. Until now, it is unknown if hydrolysis of ND into N occurs in tissue at the injection site or after systemic absorption. Therefore, hydrolysis studies were conducted to investigate the location and rate of ND hydrolysis after its release from the oil depot. ND hydrolysis was studied in porcine tissues, to mimic the human muscular and subcutaneous tissues. Additionally, the ND hydrolysis was studied in human whole blood, plasma and serum at a concentration range of 23.3-233.3μM. ND hydrolysis only occurred in human whole blood. The hydrolysis did not start immediately, but after a lag time. The mean lag time for all studied concentrations was 34.9±2.5min. Because of a slow penetration into tissue, hydrolysis of ND is found to be very low in surrounding tissue. Therefore the local generation of the active compound is clinically irrelevant. It is argued that after injection of the oil depot, ND molecules will be transported via the lymphatic system towards lymph nodes. From here, it will enter the central circulation and within half an hour it will hydrolyse to the active N compound. Copyright © 2016 Elsevier B.V. All rights reserved.

  3. The Army Family Team Building Program: Facilitating a Transformative Learning Process--An Intrinsic Case Study

    Science.gov (United States)

    Gall, Joseph A.

    2009-01-01

    This study sought to understand how the Army Family Team Building program influences self-reliance and self-sufficiency in Army spouses as they integrate into the Army community. The purpose of the Army Family Team Building program is to empower Army spouses with knowledge and skills, which foster well-being and improve quality of life. The…

  4. Expression of Genes Related to Prostaglandin Synthesis or Signaling in Human Subcutaneous and Omental Adipose Tissue: Depot Differences and Modulation by Adipogenesis

    Directory of Open Access Journals (Sweden)

    Andréanne Michaud

    2014-01-01

    Full Text Available Objectives. (1 To examine depot-specific PGE2 and PGF2α release and mRNA expression of enzymes or receptors involved in PG synthesis or signaling in human adipose tissues; (2 to identify changes in expression of these transcripts through preadipocyte differentiation; and (3 to examine associations between adipose tissue mRNA expression of these transcripts and adiposity measurements. Methods. Fat samples were obtained surgically in women. PGE2 and PGF2α release by preadipocytes and adipose tissue explants was measured. Expression levels of mRNA coding for enzymes or receptors involved in PG synthesis or signaling were measured by RT-PCR. Results. Cultured preadipocytes and explants from omental fat released more PGE2 and PGF2α than those from the subcutaneous depot and the corresponding transcripts showed consistent depot differences. Following preadipocyte differentiation, expression of PLA2G16 and PTGER3 mRNA was significantly increased whereas COX-1, COX-2, PTGIS, and PTGES mRNA abundance were decreased in both compartments (P≤0.01 for all. Transcripts that were stimulated during adipogenesis were those that correlated best with adiposity measurements. Conclusion. Cells from the omental fat compartment release more PGE2 and PGF2α than those from the subcutaneous depot. Obesity modulates expression of PG-synthesizing enzymes and PG receptors which likely occurs through adipogenesis-induced changes in expression of these transcripts.

  5. The fatty acid profile of fat depots from Santa Inês sheep fed spineless cactus (Opuntia ficus-indica Mill.).

    Science.gov (United States)

    Costa, Roberto G; Almeida, Michelly DA; Cruz, George Rodrigo B; Beltrão Filho, Edvaldo M; Ribeiro, Neila L; Madruga, Marta S; Queiroga, Rita de Cássia Re

    2017-10-01

    Fat is the tissue that varies most in animals from both a quantitative and distribution perspective. It plays a fundamental biological role as energy storage during food scarcity. Renal, pelvic and internal fat are deposited first. These fats are used to identify fatty acid profiles that may be considered beneficial or unhealthy. The aim of this study is to evaluate the fatty acid profile of fat depots in Santa Inês sheep finished in confinement with spineless cactus in their diets. The treatments included increasing levels of spineless cactus (Opuntia fícus-indica Mill.): T1 = 0%, T2 = 30%, T3 = 50%, and T4 = 70%. The diets significantly affected the adipose depots. The orthogonal contrast between the diet with no cactus (control) and the other diets indicates that the quantity of saturated fatty acids decreased and that the levels of mono-unsaturated and polyunsaturated fatty acids increased in animals fed spineless cactus. The use of spineless cactus in the diets of Santa Inês sheep affects the lipid profile of their fat depots, reducing the quantity of saturated fatty acids and increasing the quantity of mono-unsaturated and polyunsaturated fatty acids. The fatty acid profile of the fat depots indicates that these fats can be used to formulate meat products and add economic and nutritional value to such products, which increases sheep farmers' incomes. © 2017 Society of Chemical Industry. © 2017 Society of Chemical Industry.

  6. Three cases of anaphylaxis following injection of a depot corticosteroid with evidence of IgE sensitization to macrogols rather than the active steroid

    DEFF Research Database (Denmark)

    Brandt, Nicolaj; Garvey, Lene H; Bindslev-Jensen, Ulla

    2017-01-01

    We present three cases with anaphylaxis after injection of a depot corticosteroid. First, the steroid was suspected as the elicitor, but after evaluation the excipient macrogol was found to be the elicitor. One of the patients had reactions to several unrelated drugs. Increased awareness of anaph...

  7. Ethical acceptability of offering financial incentives for taking antipsychotic depot medication: Patients' and clinicians' perspectives after a 12-month randomized controlled trial

    NARCIS (Netherlands)

    E.L. Noordraven (Ernst); M.H.N. Schermer (Maartje); P. Blanken (Peter); C.L. Mulder (Niels); A.I. Wierdsma (André)

    2017-01-01

    textabstractBackground: A randomized controlled trial 'Money for Medication'(M4M) was conducted in which patients were offered financial incentives for taking antipsychotic depot medication. This study assessed the attitudes and ethical considerations of patients and clinicians who participated in

  8. Making Weapons for the Terracotta Army

    Directory of Open Access Journals (Sweden)

    Marcos Martinón-Torres

    2011-10-01

    Full Text Available The Terracotta Army of the First Emperor of China is one of the most emblematic archaeological sites in the world. Many questions remain about the logistics of technology, standardisation and labour organisation behind the creation of such a colossal construction in just a few decades over 2,000 years ago. An ongoing research project co-ordinated between the UCL Institute of Archaeology and the Emperor Qin Shihang's Terracotta Army Museum is beginning to address some of these questions. This paper outlines some results of the typological, metric, microscopic, chemical and spatial analyses of the 40,000 bronze weapons recovered with the Terracotta Warriors. Thanks to a holistic approach developed specifically for this project, it is possible to reveal remarkable aspects of the organisation of the Qin workforce in production cells, of the standardisation, efficiency and quality-control procedures employed, and of the sophisticated technical knowledge of the weapon-makers.

  9. Automation impact study of Army Training Management

    Energy Technology Data Exchange (ETDEWEB)

    Sanquist, T.F.; Schuller, C.R.; McCallum, M.C.; Underwood, J.A.; Bettin, P.J.; King, J.L.; Melber, B.D.; Hostick, C.J.; Seaver, D.A.

    1988-01-01

    The main objectives of this impact study were to identify the potential cost savings associated with automated Army Training Management (TM), and to perform a cost-benefit analysis for an Army-wide automated TM system. A subsidiary goal was to establish baseline data for an independent evaluation of a prototype Integrated Training Management System (ITMS), to be tested in the fall of 1988. A structured analysis of TM doctrine was performed for comparison with empirical data gathered in a job analysis survey of selected units of the 9ID (MTZ) at Ft. Lewis, Washington. These observations will be extended to other units in subsequent surveys. The survey data concerning staffing levels and amount of labor expended on eight distinct TM tasks were analyzed in a cost effectiveness model. The main results of the surveys and cost effectiveness modelling are summarized. 18 figs., 47 tabs.

  10. Automation impact study of Army Training Management

    International Nuclear Information System (INIS)

    Sanquist, T.F.; Schuller, C.R.; McCallum, M.C.; Underwood, J.A.; Bettin, P.J.; King, J.L.; Melber, B.D.; Hostick, C.J.; Seaver, D.A.

    1988-01-01

    The main objectives of this impact study were to identify the potential cost savings associated with automated Army Training Management (TM), and to perform a cost-benefit analysis for an Army-wide automated TM system. A subsidiary goal was to establish baseline data for an independent evaluation of a prototype Integrated Training Management System (ITMS), to be tested in the fall of 1988. A structured analysis of TM doctrine was performed for comparison with empirical data gathered in a job analysis survey of selected units of the 9ID (MTZ) at Ft. Lewis, Washington. These observations will be extended to other units in subsequent surveys. The survey data concerning staffing levels and amount of labor expended on eight distinct TM tasks were analyzed in a cost effectiveness model. The main results of the surveys and cost effectiveness modelling are summarized. 18 figs., 47 tabs

  11. Electronic Warfare in Army Models - A Survey.

    Science.gov (United States)

    1980-08-01

    CCM) PROVING GROUND TENIAS SAMJAM EIEM SPREAD SPECTRUM US ARMY ELECTRONIC FOREIGN SCIENCE & OFFICE OF MISSILE WARFARE LAB (EWL) TECHNOLOGY CENTER...IPAR MULTIRADAR SPREAD SPECTRUM ECMFUZ IRSS OTOALOC TAC ZINGERS EIEM ITF PATCOM TAM EOCM SIM FAC MGM-H4D RFSS TENIAS GTSF MG(-H4H ROLJAM ZAP I HMSM MSL...USAFAS TRASANA USAPAS TCF ASD WPAFU TENIAS ______ ___ ECAC _________ WAR EAGLE _________CATRADA WARRANT am________ 3DBDM ZAP 1 ____________ MEW EWL ZAP 2

  12. Enhancing Army Joint Force Headquarters Capabilities

    Science.gov (United States)

    2010-01-01

    insights, advice, and support. We also would like to thank Colonel James Dickens , Army Forces Command, and Lieutenant Colonel Ted Crisco, Combined Arms... Dickens (2004a, 2004b). 17 An important point is that the individual ground and air commanders change over time (because of duty shifts or...Division G3, 1st Cavalry Division, “Task Force Baghdad: Operation Iraq Freedom II,” undated briefing. Arnas, Neyla, Charles Barry, and Robert B. Oakley

  13. Assessing the Assignment Policy for Army Women

    Science.gov (United States)

    2007-01-01

    OSD Office of the Secretary of Defense PST private security team PSYOP psychological operations ROE rules of engagement RPG rocket-propelled grenade...were snipers, RPGs [rocket-propelled grenades], and all at one time. So the convoy commander goes up the road to the box. The special- ist is in the...The Impact of Pregnancy on U.S. Army Readiness, Maxwell Air Force Base, Ala.: Air Command and Staff College, April 1999. As of February 11, 2007

  14. Should there be an Australian Army Association?

    Science.gov (United States)

    2006-12-15

    of the United States Army BAFF British Armed Forces Federation BCOF British Commonwealth Occupation Forces CAD Canadian Dollars CDA Conference of...Federation ( BAFF ) 7. The Canadian Infantry Association 23 8. The Royal Canadian Armoured Corps Association 9. The Canadian Association of Veterans in...surprising that these associations and the focus of their objects have high degrees of similarity.2 The British Armed Forces Federation ( BAFF ) is a

  15. The Army’s Local Economic Effects

    Science.gov (United States)

    2015-01-01

    Cole Sutera, Christopher Skeels The Army’s Local Economic Effects C O R P O R A T I O N Limited Print and Electronic Distribution Rights This...these components would also be reduced. Decreasing Army spending, soldiers, and government civilian positions will produce broad economic effects in...and the ripple effects , or “backward linkages,” that it supports. This report presents findings from RAND Arroyo Center research on the economic

  16. Counter - Drug: Mandate for the Army.

    Science.gov (United States)

    1991-03-01

    active and reserve forces, and restart the Military Assistance Training Advisor ( MATA ) course at Fort Bragg. (5) Provide positive examples of CONUS...reduced or no charge, and at either US or host country sites. Develop a CONUS-based training course for source country security forces (El Salvador ...JAG Judge Advocate General JRTC Joint Readiness Training Center JTF joint task force LEA law enforcement agency MACOM major Army command MATA Military

  17. PEOPLE’S LIBERATION ARMY AFTER NEXT

    Science.gov (United States)

    2000-08-01

    Zhu Rongji Says Joint Stock System is not Panacea for Rescuing State-Owned Enterprises,” Sing Tao Jih Pao, Hong Kong, December 23, 1997, p. A2. 135...Yang, “Jiang Zemin, Zhu Rongji Issue New Army Regulation,” China Daily (Internet version), July 13, 1999, FBIS OW1307033099. 33. Pei Fang. 34. Rocket...ocean monitoring ( haiyang jianshi) network for detecting and tracking naval activities, to include carrier battle groups and submarines. Development of

  18. Getting It Right: Revamping Army Talent Management

    Science.gov (United States)

    2015-06-01

    CEO Ralph Cordiner stressed the importance of decentralization and management development throughout the organization. During his reign, GE started...innovative company with impressive workforce productivity. Sullivan also stresses in the case study that each of Facebook’s unique talent management...professionals, the millennials . A. RETENTION The Army uses two robust training and college education pipelines to create its officer supply between the

  19. Army Communicator. Volume 35, Number 2

    Science.gov (United States)

    2010-01-01

    quenched-spark transmitters. The SCR-49 pack radio set could be disassembled into several components and transported by two or three Army mules . The...Although signaling meth - ods have changed radically since Myer’s day, he would be enormously proud that the Signal Corps he founded one hundred and...Wireless telegraph saw limited use, but radio sets were very bulky, heavy, and thus less mobile than wire-based meth - ods. Moreover, their signals

  20. Tactics of the Soviet Army Regiment

    Science.gov (United States)

    1979-05-14

    brasis for such a non- specific Threat. The US Army Combined Arms Combat Develop- ments Activity (CACDA) has made plans to augment this effort with...withdrawal can occur when: 0 Conducting economy of force measures. . To gain time. * To realign or "tidy-up" the battlefield. . To make available...combat power in that narrowed area. The remainder of the division would conduct economy of force measures in the rest of the zone. The attacking forces

  1. Army Reserve Capabilities-Based Prioritization Study

    Science.gov (United States)

    2008-08-15

    journal databases such as JSTOR , ABI Inform, Proquest, and Emerald; syllabi for courses in strategic management and planning at Harvard, MIT, Wharton, and...methodology for prioritization. • Secure, database repository of appropriate bins, criteria or metrics for prioritization. • Reproducible...Prioritization PPBC/SRG Initial POM Database turned over to Army Budget TGM Issued ARB Final POM/BES Decisions Price/Rate Changes Other Fact-of-Life Changes

  2. Readiness Reporting for an Adaptive Army

    Science.gov (United States)

    2013-01-01

    bring clarity and fixity to the “‘denominator,”’ i.e., the standards against which readiness is compared, particularly with regard to the meaning of FSO...definition, institutionalization, and fixity , and linking those emerging needs from the next demand signal more formally to the documents...recommendation, the Army above all would have to do the following: • Modify the readiness reporting system and AR 220-1 so as to bring clarity and fixity

  3. Fostering Creative Thinking in the Institutional Army

    Science.gov (United States)

    2016-06-10

    leadership, more specifically the US Army, identified developing creative thinkers as an essential component to the concept of winning in a complex world...Director, Graduate Degree Programs Robert F. Baumann, Ph.D. The opinions and conclusions expressed herein are those of the student author and do not...concept of winning in a complex world. This is the case because the complexity of the security environment requires agile and adaptive leaders. In order

  4. Operational, Social, and Religious Influences upon the Army Chaplain Field Manual, 1926-1952

    National Research Council Canada - National Science Library

    Nay, Robert

    2008-01-01

    The early formulation of the Army Chaplain Field Manual reveals the Army Chaplaincy struggling with individuals using the Army Chaplain Field Manual to further their social and religious beliefs upon other chaplains...

  5. Army Drawdown and Restructuring: Background and Issues for Congress

    Science.gov (United States)

    2013-01-03

    worn-out leftovers from World War II.”9 The low personnel and equipment readiness levels in 1950 became apparent during the initially weak U.S. military...the Vietnam War in 1968, the Army grew to over 1,570,000 men and women . The conscripted Army of the Vietnam War had a disproportionate...these numbers. Characterizing the Pacific region, the Army notes three of the world’s largest economies (United States, China , Japan); four of the

  6. Army Communicator. Volume 33, Number 4, Fall 2008

    Science.gov (United States)

    2008-01-01

    Wein, SPC Evan D. Marcy, SPC Kevin Doheny 10 MG Stevenson explains operational capabilities for the future Paul Wein 12 Project Mananger Mobile...DOD 314) at Augusta, Ga. 30901 and add~ional mailing offices. POSTMASTER: Send address changes to Army Communicator, U.S. Army Signal Center, Fort...elements. The content does not necessarily reflect the official U.S. Army position and does not change or supersede any information in other offi:ial

  7. Army General Fund Adjustments Not Adequately Documented or Supported

    Science.gov (United States)

    2016-07-26

    audit of the FY 1991 Army financial statements.6 The Army indicated in its FY 2008 Statement of Assurance on Internal Controls7 that this material...Accounting Service Indianapolis (DFAS Indianapolis) did not adequately support $2.8 trillion in third quarter journal voucher (JV) adjustments and...statements were unreliable and lacked an adequate audit trail. Furthermore, DoD and Army managers could not rely on the data in their accounting

  8. Closing the Candor Chasm: The Missing Element of Army Professionalism

    Science.gov (United States)

    2013-09-01

    Don M. Snider, Major Paul Oh, and Major Kevin Toner , October 2009. 2. The Army Officers’ Professional Ethic—Past, Present, and Fu- ture, by Colonel...Government Printing Office, October 2006. ____________. Army Mentorship Handbook. Roslyn, VA: Head- quarters Department of the Army Printing Office, January...Washington, DC: Head- quarters Department of the Navy Printing Office, June 1986. ____________. Training and Doctrine Command (TRADOC), The

  9. How Big Should the Army Be Considerations for Congress

    Science.gov (United States)

    2016-09-02

    How Big Should the Army Be? Considerations for Congress Lawrence Kapp, Coordinator Specialist in Military Manpower Policy Andrew Feickert... the Army Be? Considerations for Congress Congressional Research Service 2 Figure 1. Army End Strength, FY1989-2016 Source: Defense Manpower Data...strength increase—as well as what component—it is difficult to ascertain the impact on readiness. An important factor is that of operational tempo. If the

  10. Leptin deficiency-induced obesity affects the density of mast cells in abdominal fat depots and lymph nodes in mice.

    Science.gov (United States)

    Altintas, Mehmet M; Nayer, Behzad; Walford, Eric C; Johnson, Kevin B; Gaidosh, Gabriel; Reiser, Jochen; De La Cruz-Munoz, Nestor; Ortega, Luis M; Nayer, Ali

    2012-02-07

    Mast cells are implicated in the pathogenesis of obesity and insulin resistance. Here, we explored the effects of leptin deficiency-induced obesity on the density of mast cells in metabolic (abdominal fat depots, skeletal muscle, and liver) and lymphatic (abdominal lymph nodes, spleen, and thymus) organs. Fourteen-week-old male leptin-deficient ob/ob mice and their controls fed a standard chow were studied. Tissue sections were stained with toluidine blue to determine the density of mast cells. CD117/c-kit protein expression analysis was also carried out. Furthermore, mast cells containing immunoreactive tumor necrosis factor-α (TNF-α), a proinflammatory cytokine involved in obesity-linked insulin resistance, were identified by immunostaining. ob/ob mice demonstrated adiposity and insulin resistance. In abdominal fat depots, mast cells were distributed differentially. While most prevalent in subcutaneous fat in controls, mast cells were most abundant in epididymal fat in ob/ob mice. Leptin deficiency-induced obesity was accompanied by a 20-fold increase in the density of mast cells in epididymal fat, but a 13-fold decrease in subcutaneous fat. This finding was confirmed by CD117/c-kit protein expression analysis. Furthermore, we found that a subset of mast cells in epididymal and subcutaneous fat were immunoreactive for TNF-α. The proportion of mast cells immunoreactive for TNF-α was higher in epididymal than in subcutaneous fat in both ob/ob and control mice. Mast cells were also distributed differentially in retroperitoneal, mesenteric, and inguinal lymph nodes. In both ob/ob mice and lean controls, mast cells were more prevalent in retroperitoneal than in mesenteric and inguinal lymph nodes. Leptin deficiency-induced obesity was accompanied by increased mast cell density in all lymph node stations examined. No significant difference in the density of mast cells in skeletal muscle, liver, spleen, and thymus was noted between ob/ob and control mice. This study

  11. Leptin deficiency-induced obesity affects the density of mast cells in abdominal fat depots and lymph nodes in mice

    Directory of Open Access Journals (Sweden)

    Altintas Mehmet M

    2012-02-01

    Full Text Available Abstract Background Mast cells are implicated in the pathogenesis of obesity and insulin resistance. Here, we explored the effects of leptin deficiency-induced obesity on the density of mast cells in metabolic (abdominal fat depots, skeletal muscle, and liver and lymphatic (abdominal lymph nodes, spleen, and thymus organs. Fourteen-week-old male leptin-deficient ob/ob mice and their controls fed a standard chow were studied. Tissue sections were stained with toluidine blue to determine the density of mast cells. CD117/c-kit protein expression analysis was also carried out. Furthermore, mast cells containing immunoreactive tumor necrosis factor-α (TNF-α, a proinflammatory cytokine involved in obesity-linked insulin resistance, were identified by immunostaining. Results ob/ob mice demonstrated adiposity and insulin resistance. In abdominal fat depots, mast cells were distributed differentially. While most prevalent in subcutaneous fat in controls, mast cells were most abundant in epididymal fat in ob/ob mice. Leptin deficiency-induced obesity was accompanied by a 20-fold increase in the density of mast cells in epididymal fat, but a 13-fold decrease in subcutaneous fat. This finding was confirmed by CD117/c-kit protein expression analysis. Furthermore, we found that a subset of mast cells in epididymal and subcutaneous fat were immunoreactive for TNF-α. The proportion of mast cells immunoreactive for TNF-α was higher in epididymal than in subcutaneous fat in both ob/ob and control mice. Mast cells were also distributed differentially in retroperitoneal, mesenteric, and inguinal lymph nodes. In both ob/ob mice and lean controls, mast cells were more prevalent in retroperitoneal than in mesenteric and inguinal lymph nodes. Leptin deficiency-induced obesity was accompanied by increased mast cell density in all lymph node stations examined. No significant difference in the density of mast cells in skeletal muscle, liver, spleen, and thymus was

  12. An integrative transcriptomic approach to identify depot differences in genes and microRNAs in adipose tissues from high fat fed mice

    Science.gov (United States)

    Wijayatunga, Nadeeja N.; Pahlavani, Mandana; Kalupahana, Nishan S.; Kottapalli, Kameswara Rao; Gunaratne, Preethi H.; Coarfa, Cristian; Ramalingam, Latha; Moustaid-Moussa, Naima

    2018-01-01

    Obesity contributes to metabolic disorders such as diabetes and cardiovascular disease. Characterization of differences between the main adipose tissue depots, white (WAT) [including subcutaneous (SAT) and visceral adipose tissue (VAT)] and brown adipose tissue (BAT) helps to identify their roles in obesity. Thus, we studied depot-specific differences in whole transcriptome and miRNA profiles of SAT, VAT and BAT from high fat diet (HFD/45% of calories from fat) fed mice using RNA sequencing and small RNA-Seq. Using quantitative real-time polymerase chain reaction, we validated depot-specific differences in endoplasmic reticulum (ER) stress related genes and miRNAs using mice fed a HFD vs. low fat diet (LFD/10% of calories from fat). According to the transcriptomic analysis, lipogenesis, adipogenesis, inflammation, endoplasmic reticulum (ER) stress and unfolded protein response (UPR) were higher in VAT compared to BAT, whereas energy expenditure, fatty acid oxidation and oxidative phosphorylation were higher in BAT than in VAT of the HFD fed mice. In contrast to BAT, ER stress marker genes were significantly upregulated in VAT of HFD fed mice than the LFD fed mice. For the first time, we report depot specific differences in ER stress related miRNAs including; downregulation of miR-125b-5p, upregulation miR-143-3p, and miR-222-3p in VAT following HFD and upregulation of miR-30c-2-3p only in BAT following a HFD in mice than the LFD mice. In conclusion, HFD differentially regulates miRNAs and genes in different adipose depots with significant induction of genes related to lipogenesis, adipogenesis, inflammation, ER stress, and UPR in WAT compared to BAT. PMID:29507687

  13. Speaking With One Voice: Army Relations With Congress

    National Research Council Canada - National Science Library

    Ellis, Ronnie

    2003-01-01

    .... By formally incorporating its strategic communications efforts with Congressional liaison offices, the Army will not only speak with one voice on appropriations and authorization issues, but it will...

  14. Management: The Missing Link to Army Leadership Doctrine

    National Research Council Canada - National Science Library

    Flemming, Lee

    2003-01-01

    .... There are numerous applications for management in today's Army to include the developing Operational Career Fields, budget and procurement management, garrison activities, logistics sustainment, and acquisitions...

  15. Army ASSIP System of Systems Test Metrics Task

    National Research Council Canada - National Science Library

    Sledge, Carol A

    2006-01-01

    The Army Strategic Software Improvement Program goal is to dramatically improve the acquisition of software- intensive systems by focusing on acquisition programs, people, and production/sustainment...

  16. Army Secure Operating System: Information Security for Real Time Systems

    National Research Council Canada - National Science Library

    Anderson, Eric

    1984-01-01

    .... ASOS will support real time applications software coded in Ada. In addition, ASOS will incorporate information security technology to protect classified data processed by Army tactical systems...

  17. The Future Army National Guard: Easing Contemporary Challenges of Transformation

    National Research Council Canada - National Science Library

    Fuhr, Daniel J

    2006-01-01

    .... However, deliberate efforts can bring about timely, positive adaptation. This paper explores the factors bearing on cultural changes that will speed effective transformation in the Army National Guard...

  18. An Identification of Interpersonal Skills for Building Army Civilian Leaders

    National Research Council Canada - National Science Library

    Elliott, Kari A; Erickson, Michael D; Fowler, Edward T; Gieseking, John K; Weiss, Mary P

    2006-01-01

    .... This project expands the findings from the 2003 Army Training and Leadership Development Panel, Communication Task Force initiative, which identified a perceived gap in interpersonal skills exhibited...

  19. Integrating Bill of Materials Data Into the Armys Enterprise Resource Planning Systems

    Science.gov (United States)

    2016-05-17

    57 Army Sustainment November–December 2015 As the Army moves to an en-terprise resource planning ... Resource Planning Systems  By LeQuan M. Hylton TOOLS The fielding of Global Combat Support System–Army has changed the way the Army manages bill...Army), and the Army Enterprise System Integration Program (AE- SIP), BOM data is enterprise -level master data designed to be used to- gether and

  20. Mobilization of the Army National Guard and Army Reserve: Historical Perspective and the Vietnam War

    Science.gov (United States)

    1984-09-07

    31st, 37th, 40th, 43rd 44th, 45th, and 47th) and three of the 20 RCT’s (196th, 278th, and 296th). The induction strength of the eight divisions, as a...Department Hob Plan, 1923; War Department Mob Plan, 1924; War Department General Mob Plan, 1928; War Department Mob Plan, 1933; Protective Mob Plan, 1938...Guard and Army Reserve in any operation AS large as Vietnam. The Regular Army was not organized to .: induct a war without mobilization of the

  1. Prepare the Army for War. A Historical Overview of the Army Training and Doctrine Command, 1973 - 1993

    Science.gov (United States)

    1993-01-01

    Italy and the United States. Upon approval by the U.S. Army Chief of Staff, planning began immediately, and the first discussions were held in Rome in...4-11. Romjue, John L. The Army of Excellence: The Development of the 1980s Army. TRADOC Historical Monograph Series. Office of the Command Historia ...45, 46, 76, 80bilateral exchange with, 88, 89 Poland, 115, 118, 120, 121 Rome , Italy, 86 Post-conflict operations, 142, 146 Roundout brigades, 128

  2. Force Structure: Capabilities and Cost of Army Modular Force Remain Uncertain

    National Research Council Canada - National Science Library

    2006-01-01

    .... The Army's goals for increasing combat power while introducing predictability in deployments for its soldiers are important, and the Army leadership in headquarters, military and civilian staffs...

  3. Comparative analysis of field ration for military personnel of the ukrainian army and armies of other countries worldwide

    Directory of Open Access Journals (Sweden)

    M. Mardar

    2017-04-01

    Full Text Available For the purpose of improvement of the Ukrainian nutritional standards this Article provides comparative analysis of field rations of different countries worldwide to make a proposal on improvement of food-stuff assortment in food ration for military personnel in the Armed Forces of Ukraine, Army of USA, the British Army, Army of Germany, Army of Italy, Army of Canada, Army of France, Army of Belarus, Army of Armenia. In accordance with the comparative analysis it was established that ration composition used for the Armed Forces of Ukraine military personnel lags behind developed countries of the world both in nutrition arrangement and in nutrient composition, especially in relation to assortment and variety of ration food-stuff. Moreover, a field ration is strictly unified and doesn’t consider individual needs of military personnel in calories, proteins, fats, carbohydrates, food fibers. Selection of individual field ration takes to account only age of military personnel, i. e. individual needs related to nutrition composition such as physical abilities, level of physical activity, gender, type of occupation before military conscription and etc. are not consideredThe obtained results confirms practicability of assortment products assortment included to field rations for the purpose to correct nutrition rations towards optimal balance for military efficiency of army, adaptation of military personnel to physical and psychological loads.

  4. Maternal obesity programs increased leptin gene expression in rat male offspring via epigenetic modifications in a depot-specific manner.

    Science.gov (United States)

    Lecoutre, Simon; Oger, Frederik; Pourpe, Charlène; Butruille, Laura; Marousez, Lucie; Dickes-Coopman, Anne; Laborie, Christine; Guinez, Céline; Lesage, Jean; Vieau, Didier; Junien, Claudine; Eberlé, Delphine; Gabory, Anne; Eeckhoute, Jérôme; Breton, Christophe

    2017-08-01

    According to the Developmental Origin of Health and Disease (DOHaD) concept, maternal obesity and accelerated growth in neonates predispose offspring to white adipose tissue (WAT) accumulation. In rodents, adipogenesis mainly develops during lactation. The mechanisms underlying the phenomenon known as developmental programming remain elusive. We previously reported that adult rat offspring from high-fat diet-fed dams (called HF) exhibited hypertrophic adipocyte, hyperleptinemia and increased leptin mRNA levels in a depot-specific manner. We hypothesized that leptin upregulation occurs via epigenetic malprogramming, which takes place early during development of WAT. As a first step, we identified in silico two potential enhancers located upstream and downstream of the leptin transcription start site that exhibit strong dynamic epigenomic remodeling during adipocyte differentiation. We then focused on epigenetic modifications (methylation, hydroxymethylation, and histone modifications) of the promoter and the two potential enhancers regulating leptin gene expression in perirenal (pWAT) and inguinal (iWAT) fat pads of HF offspring during lactation (postnatal days 12 (PND12) and 21 (PND21)) and in adulthood. PND12 is an active period for epigenomic remodeling in both deposits especially in the upstream enhancer, consistent with leptin gene induction during adipogenesis. Unlike iWAT, some of these epigenetic marks were still observable in pWAT of weaned HF offspring. Retained marks were only visible in pWAT of 9-month-old HF rats that showed a persistent "expandable" phenotype. Consistent with the DOHaD hypothesis, persistent epigenetic remodeling occurs at regulatory regions especially within intergenic sequences, linked to higher leptin gene expression in adult HF offspring in a depot-specific manner.

  5. Nonfatal Suicidal Behaviors in U.S. Army Administrative Records, 2004-2009: Results from the Army Study to Assess Risk and Resilience in Servicemembers (Army STARRS).

    Science.gov (United States)

    Ursano, Robert J; Kessler, Ronald C; Heeringa, Steven G; Cox, Kenneth L; Naifeh, James A; Fullerton, Carol S; Sampson, Nancy A; Kao, Tzu-Cheg; Aliaga, Pablo A; Vegella, Patti; Mash, Holly Herberman; Buckley, Christina; Colpe, Lisa J; Schoenbaum, Michael; Stein, Murray B

    2015-01-01

    Although the U.S. Army suicide rate is known to have risen sharply over the past decade, information about medically documented, nonfatal suicidal behaviors is far more limited. Here we examine trends and sociodemographic correlates of suicide attempts, suspicious injuries, and suicide ideation among regular Army soldiers. Data come from the Army Study to Assess Risk and Resilience in Servicemembers (Army STARRS) Historical Administrative Data Study (HADS), which integrates administrative records for all soldiers on active duty during the years 2004 through 2009 (n = 1.66 million). We identified 21,740 unique regular Army soldiers with a nonfatal suicidal event documented at some point during the HADS study period. There were substantial increases in the annual incidence rates of suicide attempts (179-400/100,000 person-years) and suicide ideation (557-830/100,000 person-years), but not suspicious injuries. Using hierarchical classification rules to identify the first instance of each soldier's most severe behavior, we found increased risk of all outcomes among those who were female, non-Hispanic White, never married, lower-ranking enlisted, less educated, and of younger age when entering Army service. These sociodemographic associations significantly differed across outcomes, despite some patterns that appear similar. Results provide a broad overview of nonfatal suicidal trends in the U.S. Army during 2004 through 2009 and demonstrate that integration of multiple administrative data systems enriches analysis of the predictors of such events.

  6. Lifetime Suicidal Behaviors and Career Characteristics Among U.S. Army Soldiers: Results from the Army Study to Assess Risk and Resilience in Servicemembers (Army STARRS).

    Science.gov (United States)

    Millner, Alexander J; Ursano, Robert J; Hwang, Irving; King, Andrew J; Naifeh, James A; Sampson, Nancy A; Zaslavsky, Alan M; Stein, Murray B; Kessler, Ronald C; Nock, Matthew K

    2018-04-01

    The current report presents data on lifetime prevalence of suicide ideation and nonfatal attempts as reported by the large representative sample of U.S. Army soldiers who participated in the Consolidated All-Army Survey of the Army Study to Assess Risk and Resilience in Servicemembers (N = 29,982). We also examine associations of key Army career characteristics with these outcomes. Prevalence estimates for lifetime suicide ideation are 12.7% among men and 20.1% among women, and for lifetime suicide attempts are 2.5% and 5.1%, respectively. Retrospective age-of-onset reports suggest that 53.4%-70% of these outcomes had preenlistment onsets. Results revealed that, for both men and women, being in the Regular Army, compared with being in the National Guard or Army Reserve, and being in an enlisted rank, compared with being an officer, is associated with increased risk of suicidal behaviors and that this elevated risk is present both before and after joining the Army. © 2017 The American Association of Suicidology.

  7. Nonfatal Suicidal Behaviors in U.S. Army Administrative Records, 2004–2009: Results from the Army Study to Assess Risk and Resilience in Servicemembers (Army STARRS)

    Science.gov (United States)

    Ursano, Robert J.; Kessler, Ronald C.; Heeringa, Steven G.; Cox, Kenneth L.; Naifeh, James A.; Fullerton, Carol S.; Sampson, Nancy A.; Kao, Tzu-Cheg; Aliaga, Pablo A.; Vegella, Patti; Mash, Holly Herberman; Buckley, Christina; Colpe, Lisa J.; Schoenbaum, Michael; Stein, Murray B.

    2015-01-01

    Objective Although the U.S. Army suicide rate is known to have risen sharply over the past decade, information about medically documented, nonfatal suicidal behaviors is far more limited. Here we examine trends and sociodemographic correlates of suicide attempts, suspicious injuries, and suicide ideation among regular Army soldiers. Methods Data come from the Army Study to Assess Risk and Resilience in Servicemembers (Army STARRS) Historical Administrative Data Study (HADS), which integrates administrative records for all soldiers on active duty during the years 2004 through 2009 (n = 1.66 million). Results We identified 21,740 unique regular Army soldiers with a nonfatal suicidal event documented at some point during the HADS study period. There were substantial increases in the annual incidence rates of suicide attempts (179–400/100,000 person-years) and suicide ideation (557–830/100,000 person-years), but not suspicious injuries. Using hierarchical classification rules to identify the first instance of each soldier's most severe behavior, we found increased risk of all outcomes among those who were female, non-Hispanic White, never married, lower-ranking enlisted, less educated, and of younger age when entering Army service. These sociodemographic associations significantly differed across outcomes, despite some patterns that appear similar. Conclusion Results provide a broad overview of nonfatal suicidal trends in the U.S. Army during 2004 through 2009 and demonstrate that integration of multiple administrative data systems enriches analysis of the predictors of such events. PMID:26168022

  8. Commentary on "The Army Study to Assess Risk and Resilience in Servicemembers (Army STARRS)": Army STARRS: a Framingham-like study of psychological health risk factors in soldiers.

    Science.gov (United States)

    Ressler, Kerry J; Schoomaker, Eric B

    2014-01-01

    Although historically the Army suicide rate has been significantly lower than the civilian rate, in 2004, the suicide and accidental death rates began trending upward. By 2008, the Army suicide rate had risen above the national average (20.2 per 100,000). In 2009, 160 active duty Soldiers took their lives, making suicide the third leading cause of death among the Army population. If accidental death, frequently the result of high-risk behavior, is included, then more Soldiers died by their own actions than in combat in 2009. The Army Study to Assess Risk and Resilience in Servicemembers (Army STARRS) was thus created in 2009 to begin to address these problems. The Army STARRS project is a large consortium of seven different studies to develop data-driven methods for mitigating or preventing suicide behaviors and improving the overall mental health and behavioral functioning of Army Soldiers during and after their Army service. The first research articles from the Army STARRS project were published in late 2013 and early 2014. This work has already begun to outline important facets of risk in the military, and it is helping to drive an empirically derived approach to improvements in understanding mental disorders and risk behavior and to improve prevention and support of mental health and resilience. The Framingham Heart Study, started in the 1940s, marked a watershed event in utilizing large cross-sectional and prospective longitudinal collaborative research to identify and understand risk factors for cardiovascular disease. The Army STARRS project, through its collaborative, prospective, and robust innovative design and implementation, may provide the beginning of a similar scientific cohort in mental disorders. The work of this project will help understand biological and psychological aspects of military service, including those leading to suicide. When coupled with timely feedback to Army leadership, it permits near real-time steps to diagnose, mitigate, and

  9. 2015 Center for Army Leadership Annual Survey of Army Leadership (CASAL): Military Leader Findings

    Science.gov (United States)

    2016-07-01

    sports , and competitions; and recognition, awards, and incentives to motivate subordinates. Ineffective Mitigation of Workload Stress. The themes for the...Assignment Practices The assignment process is a mechanism by which the Army can utilize leadership talent and deliberately develop leadership skills...Commissioned Officer Professional Development and Career Management). Assignments are one of several aspects of how organizations employ talent

  10. Child Abuse and Neglect United States Army U.S. Army Central Registry (1989-1996)

    Science.gov (United States)

    1998-03-31

    This report is an analysis of the child abuse and neglect cases that have been recorded in the Army Central Registry between 1989-1996. The following...were 30,551 initial substantiated cases of child abuse and neglect, or an average of about 3,80 cases per year. There were 2,336 subsequent incidents

  11. A quantification of the physiological demands of the army emergency responder in the Australian army.

    Science.gov (United States)

    Tofari, Paul J; Laing Treloar, Alison K; Silk, Aaron J

    2013-05-01

    The Australian Defence Force is reviewing the physical demands of all employment categories in the Australian Army to establish valid and legally defensible assessments. The current assessments, performed in physical training attire, are not specific to job demands. Moreover, the fitness standards decrease based on age and are lower for females, and as job requirements are constant, these assessments are counterintuitive. With regard to the Army Emergency Responder employment category, tasks of physical demand in the present study were selected through consultation with subject-matter experts. Participants consisted of 10 qualified Army Emergency Responder soldiers and three noncareer firefighters under instruction. Real-life firefighting scenarios were witnessed by researchers and helped form task simulations allowing measurement of heart rate and oxygen consumption. Peak oxygen consumption ranged from 21.8 ± 3.8 to 40.0 ± 3.4 mL kg(-1) min(-1) during cutting activities and a search and rescue task, respectively, representing values similar to or higher than the current entry standards. Manual handling tasks were also assessed, with the heaviest measured being two soldiers lifting a 37.7-kg Utility Trunk to 150 cm. The findings provide a quantitative assessment of the physiological demands of Army Emergency Responders, and highlight the need for change in current fitness assessments. Reprint & Copyright © 2013 Association of Military Surgeons of the U.S.

  12. Pre-retirement education programme for Nigerian army personnel ...

    African Journals Online (AJOL)

    This study examines and describes the need for pre-retirement education programme for Nigerian Army personnel in 1 Mechanised Division, Kaduna. An investigation was carried out into the contents of such pre-retirement programme. A sample of 78 male and female army personnel was purposively selected from the ...

  13. Army Response Letter & Analysis - signed January 19, 2001

    Science.gov (United States)

    A response to the letter, which requested a review of the proposed decision by the Army Corps of Engineers Baltimore District to issue four Department of the Army permits to Baltimore County (3 permits) and Anne Arundel County (1 permit), MD.

  14. Netherlands Army Long Range Anti Armour Study - Status Report

    NARCIS (Netherlands)

    Schagen, P.A.B. van

    1989-01-01

    At the end of the nineties the munition for the TOW weapon system in use at The Netherlands army, has to be replaced. The Life of Type of The Tow carrier ends in 2005. The long range anti armour study is to gain insight into the possibilities and limitations for the Netherlands army to deploy future

  15. Army Drawdown and Restructuring: Background and Issues for Congress

    Science.gov (United States)

    2014-02-28

    as “worn-out leftovers from World War II.” The low personnel and equipment readiness levels in Army Drawdown and Restructuring: Background and...grew to over 1,570,000 men and women . The conscripted Army of the Vietnam War had a disproportionate representation of lower-income and non- college

  16. A Preliminary Anthropometry Standard for Australian Army Equipment Evaluation

    Science.gov (United States)

    2014-08-01

    UNCLASSIFIED UNCLASSIFIED A Preliminary Anthropometry Standard for Australian Army Equipment Evaluation Mark Edwards, Alistair Furnell...Jemma Coleman and Sheena Davis Land Division Defence Science and Technology Organisation DSTO-TR-3006 ABSTRACT Anthropometry is the...Preliminary Anthropometry Standard for Australian Defence Force Army Equipment Evaluation Executive Summary Anthropometry is the

  17. Army Sustainment. Volume 41, Issue 5, September-October 2009

    Science.gov (United States)

    2009-10-01

    indeed end and that the United States would emerge from it as the only superpower on the planet . And yet the peace dividend at the end of the Cold War...Army 21 and its sup- porting vision, Log 21, presented design-of-the-future prospects, with the Army beginning to invest heav - ily in these

  18. An Organizational Climate Assessment of the Army Contracting Workforce

    Science.gov (United States)

    2016-12-01

    within high quality relationships are psychological safety, which focuses on learning from failures, and the other concerning perceived organizational ...measurement and interpretation of organizational climate. The Journal of Psychology , 145(2), 93–109. U.S. Army Acquisition Corps. (2011, May). Defense...NAVAL POSTGRADUATE SCHOOL MONTEREY, CALIFORNIA MBA PROFESSIONAL REPORT AN ORGANIZATIONAL CLIMATE ASSESSMENT OF THE ARMY CONTRACTING WORKFORCE

  19. A Candidate Army Energy and Water Management Strategy

    National Research Council Canada - National Science Library

    Fournier, Donald F; Westervelt, Eileen T

    2004-01-01

    .... This work augments on-going energy and water management initiatives within the Army by developing a new candidate Army level strategy that responds to anticipated legislation; reflects current DOD and DA requirements, vision, and values in light of the current world situation; incorporates sound science and management principles; and organizes and focuses efforts into an integrated program.

  20. Army Medicine’s Role in Strength & Resilience

    Science.gov (United States)

    2011-01-24

    Resiliency Programs Physical Mental Spiritual Army Wellness Center Comprehensive Soldier Fitness Resiliency UNCLASSIFIED Comprehensive Pain ...Management  Evidence-Based Complimentary and Alternative Therapeutic Modes  Acupuncture  Biofeedback  Yoga  Meditation  Standardizes Pain Management...UNCLASSIFIED Army Strong More than a Slogan… the Key to Resilience Report Documentation Page Form ApprovedOMB No. 0704-0188 Public reporting burden

  1. 1980 Summer Study on Statistical Techniques in Army Testing.

    Science.gov (United States)

    1980-07-01

    WASHINGTON, D. C. 20310 f ARMY CIENCE BOARD 1980 SUMMER STUDY ON STATISTICAL TECHNIQUES IN ARMY TESTING JULY 1980 DTICS ELECTE NOV 2 5 1980 B _STRI...statisticians is adequate, and in some cases, excellent. In the areas of education and the dissemination of information, the Study Group found that the

  2. The Advance on Rome of the Fifth Army

    Science.gov (United States)

    2011-01-01

    and Mis. SENTINELLA, SALERIA and PILOCCO on 30 May with GOUMS ar riving before CARPINETO. Relief of the 88th Infantry Division in the NORMA ...southern GARIGLIANO front iso lated. The Fourteenth German Army Headquarters was destroyed and the German Army Group Headquarters seriously damaged

  3. Arms Transfers to the Irish Republican Army.

    Science.gov (United States)

    1987-06-01

    TERMS (Continue on ,everse of necesmary and identify by block numbe... VELD GROUP SUB-GROUP KEY WORDS: Irish Republican Army, IRA, Arms Transfers...Lrm,- r-t ." - ’,...... .. a farmhouse In -cun.y An+r:m. ."," S-t The arms were ingeniously hidden. A furniture van with a secret compartment capable...McMahon, William Westerlund, and Francis M. Larkin] and two from Ireland ’ Henry Hillick and James Conlon], were charged :n 2" with shipping 175 semi

  4. White Paper 1983: The Army Family

    Science.gov (United States)

    1983-08-15

    support. 4 "+1° I t I " I j The advent of the All Volunteer Force caused the Army’s leaders to address military personnel policies from a new...Children Children w/ Teens Gone Retirement 36.3% 16.6% 37.5% 9.3% 0.2% 17 24 18 30 20 35 36 50 51 59 60 i FIGURE 6 7 I - - .-, *L II...remarriage in their families. Another significant change has been delayed or foregone childbearing . Birthrates in the United States have declined

  5. Study of Army Design Hover Criteria

    Science.gov (United States)

    2017-09-01

    capability for U.S. Army helicopters? This question was answered in 1970 by Robert Bellaire and Lieutenant William Bousman for the development of the...helicopters? This question was answered in 1970 by Robert Bellaire and Lieutenant William Bousman for the development of the Army’s 2nd generation of...MAX Figure 15. California 0 10 20 30 40 50 60 70 80 90 100 WIN SPR SUM AUT Seasons Pe rc en t H og e MIN AVG MAX Figure 16. California

  6. Fiscal Year 2011 United States Army Annual Financial Report. America’s Army: At a Strategic Crossroads

    Science.gov (United States)

    2011-01-01

    effective. Comprehensive efforts are being aggresively engaged to reform the Army’s procurement methods with the following goal: to develop and...Research and Development Center; (3) the Army Medical Research and Materiel Command laboratories; and, (4) the Army Research Institute for Behavioral and

  7. The Transition From "Be All You Can Be" to "An Army of One" - Strategic Outreach Campaigns for Recruiting America's All-Volunteer Army and Army Reserve

    National Research Council Canada - National Science Library

    Sawyer, Jayson D

    2005-01-01

    ... in sufficient quantity and quality to man the force. The unveiling of this latest Strategic Outreach program primarily directed by the outgoing Secretary of the Army Honorable Louis Caldera in conjunction with the support...

  8. Optimal construction of army ant living bridges.

    Science.gov (United States)

    Graham, Jason M; Kao, Albert B; Wilhelm, Dylana A; Garnier, Simon

    2017-12-21

    Integrating the costs and benefits of collective behaviors is a fundamental challenge to understanding the evolution of group living. These costs and benefits can rarely be quantified simultaneously due to the complexity of the interactions within the group, or even compared to each other because of the absence of common metrics between them. The construction of 'living bridges' by New World army ants - which they use to shorten their foraging trails - is a unique example of a collective behavior where costs and benefits have been experimentally measured and related to each other. As a result, it is possible to make quantitative predictions about when and how the behavior will be observed. In this paper, we extend a previous mathematical model of these costs and benefits to much broader domain of applicability. Specifically, we exhibit a procedure for analyzing the optimal formation, and final configuration, of army ant living bridges given a means to express the geometrical configuration of foraging path obstructions. Using this procedure, we provide experimentally testable predictions of the final bridge position, as well as the optimal formation process for certain cases, for a wide range of scenarios, which more closely resemble common terrain obstacles that ants encounter in nature. As such, our framework offers a rare benchmark for determining the evolutionary pressures governing the evolution of a naturally occurring collective animal behavior. Copyright © 2017 Elsevier Ltd. All rights reserved.

  9. Prior Mental Disorders and Lifetime Suicidal Behaviors Among US Army Soldiers in the Army Study to Assess Risk and Resilience in Servicemembers (Army STARRS).

    Science.gov (United States)

    Millner, Alexander J; Ursano, Robert J; Hwang, Irving; J King, Andrew; Naifeh, James A; Sampson, Nancy A; Zaslavsky, Alan M; Stein, Murray B; Kessler, Ronald C; Nock, Matthew K

    2017-09-19

    We report on associations of retrospectively reported temporally prior mental disorders and Army career characteristics with subsequent first onset of suicidal behaviors in a large, representative sample of US Army soldiers who participated in the Consolidated All-Army Survey of the Army Study to Assess Risk and Resilience in Servicemembers (N = 29,982). Results reveal that among men and women, all self-reported lifetime disorders measured (some assessed with screening scales) are associated with subsequent onset of suicide ideation. Among men, three disorders characterized by agitation and impulsiveness (intermittent explosive disorder, panic disorder, and substance disorders) predict the transition from suicide ideation to attempt. For both men and women, being in the Regular Army (vs. National Guard or Army Reserve) predicts suicide attempts in the total sample. For men, a history of deployment and junior rank are predictors of suicide attempts after adjusting for preenlistment disorders but not accounting for pre- and postenlistment disorders, suggesting that postenlistment disorders account for some of the increased suicide risk among these career characteristics. Overall, these results highlight associations between mental disorders and suicidal behaviors, but underscore limitations predicting which people with ideation attempt suicide. © 2017 The American Association of Suicidology.

  10. 78 FR 21919 - Finding of No Significant Impact and Final Programmatic Environmental Assessment for Army 2020...

    Science.gov (United States)

    2013-04-12

    ... DEPARTMENT OF DEFENSE Department of the Army Finding of No Significant Impact and Final Programmatic Environmental Assessment for Army 2020 Force Structure Realignment AGENCY: Department of the Army, DoD. ACTION: Notice of Availability. SUMMARY: The Department of the Army announces the availability...

  11. 32 CFR 553.7 - Design and layout of Army national cemeteries.

    Science.gov (United States)

    2010-07-01

    ... 32 National Defense 3 2010-07-01 2010-07-01 true Design and layout of Army national cemeteries... RESERVATIONS AND NATIONAL CEMETERIES ARMY NATIONAL CEMETERIES § 553.7 Design and layout of Army national cemeteries. (a) General cemetery layout plans, landscape planting plans and gravesite layout plans for Army...

  12. The watershed-scale optimized and rearranged landscape design (WORLD) model and local biomass processing depots for sustainable biofuel production: Integrated life cycle assessments

    Energy Technology Data Exchange (ETDEWEB)

    Eranki, Pragnya L.; Manowitz, David H.; Bals, Bryan D.; Izaurralde, Roberto C.; Kim, Seungdo; Dale, Bruce E.

    2013-07-23

    An array of feedstock is being evaluated as potential raw material for cellulosic biofuel production. Thorough assessments are required in regional landscape settings before these feedstocks can be cultivated and sustainable management practices can be implemented. On the processing side, a potential solution to the logistical challenges of large biorefi neries is provided by a network of distributed processing facilities called local biomass processing depots. A large-scale cellulosic ethanol industry is likely to emerge soon in the United States. We have the opportunity to influence the sustainability of this emerging industry. The watershed-scale optimized and rearranged landscape design (WORLD) model estimates land allocations for different cellulosic feedstocks at biorefinery scale without displacing current animal nutrition requirements. This model also incorporates a network of the aforementioned depots. An integrated life cycle assessment is then conducted over the unified system of optimized feedstock production, processing, and associated transport operations to evaluate net energy yields (NEYs) and environmental impacts.

  13. Monitoring and documentation of side effects from depot antipsychotic medication: an interdisciplinary audit of practice in a regional mental health service.

    LENUS (Irish Health Repository)

    Cleary, A

    2012-01-01

    The aim of this audit was to review current practice within a rural mental health service area on the monitoring and documentation of side effects of antipsychotic depot medication. Following a review of the literature on best practice internationally, an evidence based audit tool was adapted. A sample of 60 case files, care plans and prescriptions were audited between January and May 2010. This represented 31% of the total number of service users receiving depot injections in the mental health service region (n=181). The audit results revealed that most service users had an annual documented medical review and a documented prescription. However, only 5 (8%) case notes examined had documentation recorded describing the condition of the injection site and alternation of the injection site was recorded in only 28 (47%) case notes. No case notes examined had written consent to commence treatment recorded, and only 3 (5%) of case notes had documented that information on the depot injection and side effects was given. In 57 (95%) of case notes no documentation of recorded information on the depot and on side effects was given. Documentation of physical observations and tests revealed that 58% of cases had full blood count, liver function tests, thyroid function tests and fasting lipids recorded. All other tests (i.e. temperature, pulse, respirations, blood pressure, ECG) were recorded in less than 50% of cases. Prolactin levels were not recorded in any case. The lack of written consent was partly attributed to lack of recording of consent. The failure to monitor and record some\\r\

  14. Incorporating Maritime Stakeholder Perspectives for Implementing an ‘Inland-Depots-for-Empty-Containers’ System Using an Analytic Hierarchy Process

    OpenAIRE

    Neha Mittal; Maria Boilé; Alok Baveja; Sotiris Theofanis

    2013-01-01

    Container movement involves several stakeholders where each group is focused on achieving its own objectives. By actively considering the perspective of different maritime stakeholders, this paper identifies a set of implementation strategies and prioritizes them to successfully implement an ‘Inland-Depots-for-Empty-Containers’ (IDEC) system in a region. It builds on the authors’ earlier work that developed and evaluated an IDEC system to minimize the overall system costs associated wit...

  15. The Army study to assess risk and resilience in servicemembers (Army STARRS).

    Science.gov (United States)

    Ursano, Robert J; Colpe, Lisa J; Heeringa, Steven G; Kessler, Ronald C; Schoenbaum, Michael; Stein, Murray B

    2014-01-01

    IMPORTANCE/OBJECTIVE: Although the suicide rate in the U.S. Army has traditionally been below age-gender matched civilian rates, it has climbed steadily since the beginning of the Iraq and Afghanistan conflicts and since 2008 has exceeded the demographically matched civilian rate. The Army Study to Assess Risk and Resilience in Servicemembers (Army STARRS) is a multicomponent epidemiological and neurobiological study designed to generate actionable evidence-based recommendations to reduce Army suicides and increase knowledge about risk and resilience factors for suicidality and its psychopathological correlates. This paper presents an overview of the Army STARRS component study designs and of recent findings. DESIGN/SETTING/PARTICIPANTS/INTERVENTION: Army STARRS includes six main component studies: (1) the Historical Administrative Data Study (HADS) of Army and Department of Defense (DoD) administrative data systems (including records of suicidal behaviors) for all soldiers on active duty 2004-2009 aimed at finding administrative record predictors of suicides; (2) retrospective case-control studies of fatal and nonfatal suicidal behaviors (each planned to have n = 150 cases and n = 300 controls); (3) a study of new soldiers (n = 50,765 completed surveys) assessed just before beginning basic combat training (BCT) with self-administered questionnaires (SAQ), neurocognitive tests, and blood samples; (4) a cross-sectional study of approximately 35,000 (completed SAQs) soldiers representative of all other (i.e., exclusive of BCT) active duty soldiers; (5) a pre-post deployment study (with blood samples) of soldiers in brigade combat teams about to deploy to Afghanistan (n = 9,421 completed baseline surveys), with sub-samples assessed again one, three, and nine months after returning from deployment; and (6) a pilot study to follow-up SAQ respondents transitioning to civilian life. Army/DoD administrative data are being linked prospectively to the large-scale survey

  16. [Medical research in the US Armed Forces (Report 3). The US Army].

    Science.gov (United States)

    Agapitov, A A; Aleĭnikov, S I; Bolekhan, V I; Ivchenko, I V; Krassiĭ, A B; Nagibovich, O A; Petrov, S V; Rezvantsev, M V; Soldatov, E A; Shalakhin, R A; Sheppli, E V

    2012-12-01

    The US Army. The present article is the third part of the review dedicated to organization and management of medical research in the US Armed Forces. The first and the second parts have been published in the previous issuses of the journal. Specifically this article is dedicated to organization and management of medical research in the US Army. It is shown that in the US Army the medical and biological research is conducted and coordinated by the special US Army Medical Research and Materiel Command. The following units are successively presented: US Army Institute of Surgical Research, US Army Medical Research Institute of Chemical Defense, US Army Medical Research Institute of Infectious Diseases, US Army Research Institute of Environmental Medicine, Walter Reed Army Institute of Research, US Army Aeromedical Research Laboratory, Armed Forces Institute of Regenerative Medicine. The particular research programs conducting in the above mentioned institutions are presented.

  17. Effect of Buprenorphine Weekly Depot (CAM2038) and Hydromorphone Blockade in Individuals With Opioid Use Disorder: A Randomized Clinical Trial.

    Science.gov (United States)

    Walsh, Sharon L; Comer, Sandra D; Lofwall, Michelle R; Vince, Bradley; Levy-Cooperman, Naama; Kelsh, Debra; Coe, Marion A; Jones, Jermaine D; Nuzzo, Paul A; Tiberg, Fredrik; Sheldon, Behshad; Kim, Sonnie

    2017-09-01

    Buprenorphine is an efficacious, widely used treatment for opioid use disorder (OUD). Daily oral transmucosal formulations can be associated with misuse, diversion, and nonadherence; these limitations may be obviated by a sustained release formulation. To evaluate the ability of a novel, weekly, subcutaneous buprenorphine depot formulation, CAM2038, to block euphorigenic opioid effects and suppress opioid withdrawal in non-treatment-seeking individuals with OUD. This multisite, double-blind, randomized within-patient study was conducted at 3 controlled inpatient research facilities. It involved 47 adults with DSM-V moderate-to-severe OUD. The study was conducted from October 12, 2015 (first patient enrolled), to April 21, 2016 (last patient visit). A total of five 3-day test sessions evaluated the response to hydromorphone (0, 6, and 18 mg intramuscular in random order; 1 dose/session/day). After the first 3-day session (ie, qualification phase), participants were randomized to either CAM2038 weekly at 24 mg (n = 22) or 32 mg (n = 25); the assigned CAM2038 dose was given twice, 1 week apart (day 0 and 7). Four sets of sessions were conducted after randomization (days 1-3, 4-6, 8-10, and 11-13). The primary end point was maximum rating on the visual analog scale for drug liking. Secondary end points included other visual analog scale (eg, high and desire to use), opioid withdrawal scales, and physiological and pharmacokinetic outcomes. A total of 46 of 47 randomized participants (mean [SD] age, 35.5 [9] years; 76% male [n = 35]) completed the study. Both weekly CAM2038 doses produced immediate and sustained blockade of hydromorphone effects (liking maximum effect, CAM2038, 24 mg: effect size, 0.813; P withdrawal (Clinical Opiate Withdrawal Scale, CAM2038, 24 mg: effect size, 0.617; P opioid blockade and withdrawal suppression. The results support the use of this depot formulation for treatment initiation and stabilization of patients with OUD, with

  18. Differential Development of Inflammation and Insulin Resistance in Different Adipose Tissue Depots Along Aging in Wistar Rats: Effects of Caloric Restriction.

    Science.gov (United States)

    Sierra Rojas, Johanna X; García-San Frutos, Miriam; Horrillo, Daniel; Lauzurica, Nuria; Oliveros, Eva; Carrascosa, Jose María; Fernández-Agulló, Teresa; Ros, Manuel

    2016-03-01

    The prevalence of insulin resistance and type 2 diabetes increases with aging and these disorders are associated with inflammation. Insulin resistance and inflammation do not develop at the same time in all tissues. Adipose tissue is one of the tissues where inflammation and insulin resistance are established earlier during aging. Nevertheless, the existence of different fat depots states the possibility of differential roles for these depots in the development of age-associated inflammation and insulin resistance. To explore this, we analyzed insulin signaling and inflammation in epididymal, perirenal, subcutaneous, and brown adipose tissues during aging in Wistar rats. Although all tissues showed signs of inflammation and insulin resistance with aging, epididymal fat was the first to develop signs of inflammation and insulin resistance along aging among white fat tissues. Subcutaneous adipose tissue presented the lowest degree of inflammation and insulin resistance that developed latter with age. Brown adipose tissue also presented latter insulin resistance and inflammation but with lower signs of macrophage infiltration. Caloric restriction ameliorated insulin resistance and inflammation in all tissues, being more effective in subcutaneous and brown adipose tissues. These data demonstrate differential susceptibility of the different adipose depots to the development of age-associated insulin resistance and inflammation. © The Author 2015. Published by Oxford University Press on behalf of The Gerontological Society of America. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  19. Designing and implementing the Army Nursing Leader Academy.

    Science.gov (United States)

    Dunemn, Kathleen; Hopkins-Chadwick, Denise L; Connally, Tina; Bramley, Kelly

    2011-01-01

    In 2008, the Chief of the Army Nurse Corps directed a thorough review of existing training programs available to and provided for Army Nursing personnel for the development of full-spectrum leaders for Army Nursing. The review provided the gap analysis necessary to restructure courses provided by the Department of Nursing Science at the Army Medical Department Center and School. This new grouping of courses is referred to as the Army Nursing Leader Academy. The Army Nursing Leader Academy is the first of its kind in that it addresses career-long learning of all Army Nursing by focusing on building skills, knowledge, and behaviors to produce sustainable, full-spectrum leaders. The Nursing Leader Academy consists of a series of sequential nurse leader development courses combined with a web based resource center. Grounded in the Patient CaringTouch System, guided by nurse competencies, and gauged by the Leader Capabilities Map, the Nursing Leader Academy provides learning that is relevant and timely designed to reinforce enterprise values and culture to ensure readiness for successive roles and positions. Full implementation of the Nursing Leader Academy will include the evidence-based elements of formal schooling, coaching, self-development, functional/technical (competency attainment), and professional experiences.

  20. The Army rolls through Indianapolis: Fieldwork at the Virtual Army Experience

    Directory of Open Access Journals (Sweden)

    Robertson Allen

    2009-03-01

    Full Text Available This essay takes an ethnographic look at the individuals and institutions associated with the development, production, and implementation of the Virtual Army Experience (VAE, a mobile mission simulator that travels across the United States to venues such as state fairs and air shows. As an explicit aid to Army recruitment and interaction with the public, the VAE is an interesting nexus point that often channels public anxieties surrounding the medium of the video game and its role in the militarization of society. Here, I present my own experience of doing ethnography at this site, describing how it is received by visitors and interpreted by its employees. By means of the example of the VAE, I argue that polarizing media reports and academic criticisms that pit the processes of militarization against critical reflection of those processes are counterproductive and result in silencing more nuanced and thoughtful critical reflection that is already present at sites such as the VAE.

  1. US Army Research Laboratory and University of Notre Dame Distributed Sensing: Hardware Overview

    Science.gov (United States)

    2017-11-01

    ARL-TR-8199 ● NOV 2017 US Army Research Laboratory US Army Research Laboratory and University of Notre Dame Distributed Sensing...US Army Research Laboratory US Army Research Laboratory and University of Notre Dame Distributed Sensing: Hardware Overview by Roger P...TITLE AND SUBTITLE US Army Research Laboratory and University of Notre Dame Distributed Sensing: Hardware Overview 5a. CONTRACT NUMBER 5b. GRANT

  2. Building A Better Force: Regular Army / Reserve Components Integration In The Army Chemical Corps

    Science.gov (United States)

    2016-05-26

    Fort Hood , TX, CPT Mike Larmore cased the colors of the 46th Chemical Company for the last time, signifying its inactivation from the Regular Army... Joshua E. Kastenberg, Shaping US Military Law: Governing a Constitutional Military, (Surrey, England: Ashgate, 2014), 204-5, accessed December 28, 2015...Kastenberg, Joshua E. Shaping US Military Law: Governing a Constitutional Military. Surrey, England: Ashgate, 2014. Accessed December 28, 2015

  3. US Colored Troops: A Model for US Army Foreign Army Development and Organization

    Science.gov (United States)

    Over the course of the Civil War, 186,000 former slaves and freedmen of African descent served in the Union Army designated as US Colored Troops...procedures, recruited, raised, trained, and organized a predominantly uneducated force for military service. The United States Colored Troops was a...force built from a population considered second class inhabitants at best, property at worst. Besides the color barrier, the white populace, government

  4. Netherlands Army Long Range Anti Armour Study - Status Report

    OpenAIRE

    Schagen, P.A.B. van

    1989-01-01

    At the end of the nineties the munition for the TOW weapon system in use at The Netherlands army, has to be replaced. The Life of Type of The Tow carrier ends in 2005. The long range anti armour study is to gain insight into the possibilities and limitations for the Netherlands army to deploy future (time period 1995-2000) weapon systems in the long range anti armour battle. The first study results are expected at the end of 1989. The study is sponsored by the Netherlands army and is carried ...

  5. Iron elevation and adipose tissue remodeling in the epididymal depot of a mouse model of polygenic obesity.

    Directory of Open Access Journals (Sweden)

    Xiaoya Ma

    Full Text Available Iron dysregulation is a potential contributor to the pathology of obesity-related metabolic complications. KK/HIJ (KK mice, a polygenic obese mouse model, have elevated serum iron levels. A subset of KK male mice display a bronzing of epididymal adipose tissue (eAT associated with >100-fold (p0.05. The eAT histology revealed iron retention, macrophage clustering, tissue fibrosis, cell death as well as accumulation of HIF-2α in the high iron eAT. qPCR showed significantly decreased Lep (leptin and AdipoQ (adiponectin, whereas Tnfα (tumor necrosis factor α, and Slc40a1 (ferroportin were up-regulated in HI (p<0.05. Elevated HIF-2α, oxidative stress and local insulin signaling loss was also observed.Our data suggest that deposition of iron in adipose tissue is limited to the epididymal depot in male KK mice. A robust adipose tissue remodeling is concomitant with the high iron concentration, which causes local adipose tissue insulin resistance.

  6. Safety and tolerability of depot medroxyprogesterone acetate among HIV-infected women on antiretroviral therapy: ACTG A5093.

    Science.gov (United States)

    Watts, D Heather; Park, Jeong-Gun; Cohn, Susan E; Yu, Song; Hitti, Jane; Stek, Alice; Clax, Pamela A; Muderspach, Laila; Lertora, Juan J L

    2008-02-01

    Concomitant use of antiretroviral (ARV) and hormonal contraceptives may change the metabolism of each and the resulting safety profiles. We evaluated the safety and tolerability of depot medroxyprogesterone acetate (DMPA) among women on ARV. HIV-infected women on selected ARV regimens or no ARV were administered DMPA 150 mg intramuscularly and evaluated for 12 weeks for adverse events, changes in CD4+ count and HIV RNA levels, and ovulation. Seventy evaluable subjects were included, 16 on nucleoside only or no ARV, 21 on nelfinavir-containing regimens, 17 on efavirenz-containing regimens and 16 on nevirapine-containing regimens. Nine Grade 3 or 4 adverse events occurred in seven subjects; none were judged related to DMPA. The most common findings possibly related to DMPA were abnormal vaginal bleeding (nine, 12.7%), headache (three, 4.2%), abdominal pain, mood changes, insomnia, anorexia and fatigue, each occurring in two (2.9%) subjects. No significant changes in CD4+ count or HIV RNA levels occurred with DMPA. No evidence of ovulation was detected, and no pregnancies occurred. The clinical profile associated with DMPA administration in HIV-infected women, most on ARV, appears similar to that seen in HIV-uninfected women. DMPA prevented ovulation and did not affect CD4+ counts or HIV RNA levels. In concert with previously published DMPA/ARV interaction data, these data suggest that DMPA can be used safely by HIV-infected women on the ARV studied.

  7. Rats and rabbits as pharmacokinetic screening tools for long acting intramuscular depots: Case study with paliperidone palmitate suspension.

    Science.gov (United States)

    Patel, Harilal; Patel, Prakash; Modi, Nirav; Patel, Pinakin; Wagh, Yogesh; George, Alex; Desai, Nirmal; Srinivas, Nuggehally R

    2018-04-12

    1. Development of prodrug of paliperidone (9-hydroxyrisperidone) long-acting intramuscular injection has enabled delivery over 4-week time period with improved compliance. 2. Key aim of work was to establish a reliable preclinical model which may potentially serve as a screening tool for judging the pharmacokinetics of paliperidone formulation(s) prior to human clinical work. 3. Sparse sampling composite study was used in rats, (Wistar/Sprague-Dawley (n = 10)). A serial blood sampling study design was used in rabbits (n = 4). Animals received intramuscular injection of paliperidone palmitate in the thigh muscle at dose of 16 (rats) and 4.5 mg/kg (rabbits). Samples were drawn in rats (retro-orbital sinus) and rabbits (central ear artery) and analysed for paliperidone using LC-MS/MS assay. The plasma data was subjected to pharmacokinetic analysis. 4. Following intramuscular injection of depot formulation in Wistar/SD rats and rabbits, absorption of paliperidone was slow and gradual with median value of T max occurring on day 7. The exposures (i.e., AUC (0-28) days) were 18597 (Wistar), 21865 (SD) and 18120 (rabbits) ng.h/mL, in Wistar, SD and rabbits, respectively. The clearance was slow and supported long half-life (8-10 days). 5. Either one of the two models can serve as a research tool for establishing pharmacokinetics of paliperidone formulation(s).

  8. LRP5 regulates human body fat distribution by modulating adipose progenitor biology in a dose- and depot-specific fashion.

    Science.gov (United States)

    Loh, Nellie Y; Neville, Matt J; Marinou, Kyriakoula; Hardcastle, Sarah A; Fielding, Barbara A; Duncan, Emma L; McCarthy, Mark I; Tobias, Jonathan H; Gregson, Celia L; Karpe, Fredrik; Christodoulides, Constantinos

    2015-02-03

    Common variants in WNT pathway genes have been associated with bone mass and fat distribution, the latter predicting diabetes and cardiovascular disease risk. Rare mutations in the WNT co-receptors LRP5 and LRP6 are similarly associated with bone and cardiometabolic disorders. We investigated the role of LRP5 in human adipose tissue. Subjects with gain-of-function LRP5 mutations and high bone mass had enhanced lower-body fat accumulation. Reciprocally, a low bone mineral density-associated common LRP5 allele correlated with increased abdominal adiposity. Ex vivo LRP5 expression was higher in abdominal versus gluteal adipocyte progenitors. Equivalent knockdown of LRP5 in both progenitor types dose-dependently impaired β-catenin signaling and led to distinct biological outcomes: diminished gluteal and enhanced abdominal adipogenesis. These data highlight how depot differences in WNT/β-catenin pathway activity modulate human fat distribution via effects on adipocyte progenitor biology. They also identify LRP5 as a potential pharmacologic target for the treatment of cardiometabolic disorders. Copyright © 2015 The Authors. Published by Elsevier Inc. All rights reserved.

  9. Oil fuel delivery optimization for multi product and multi depot: the case of petrol station replenishment problem (PSRP)

    Science.gov (United States)

    Surjandari, Isti; Rachman, Amar; Dianawati, Fauzia; Wibowo, R. Pramono

    2011-10-01

    With the Oil and Gas Law No. 22 of 2001, national and foreign private enterprises can invest in all sectors of Oil and Gas in Indonesia. In anticipation of this free competition, Pertamina, as a state-owned enterprises, which previously had monopolized the oil and gas business activities in Indonesia, should be able to improve services as well as the efficiency in order to compete in the free market, especially in terms of cost efficiency of fuel distribution to gas station (SPBU). To optimize the distribution activity, it is necessary to design a scheduling system and its fuel delivery routes daily to every SPBU. The determination of routes and scheduling delivery of fuel to the SPBU can be modeled as a Petrol Station Replenishment Problem (PSRP) with the multi-depot, multi-product, time windows and split deliveries, which in this study will be completed by the Tabu Search algorithm (TS). This study was conducted in the area of Bandung, the capital of West Java province, which is a big city and the neighboring city of Jakarta, the capital city of Indonesia. By using the fuel delivery data for one day, the results showed a decrease of 16.38% of the distance of the route compared to the current conditions, which impacted on the reduction of distribution costs and decrease the number of total trips by 5.22% and 3.83%.

  10. Improving beef hamburger quality and fatty acid profiles through dietary manipulation and exploitation of fat depot heterogeneity.

    Science.gov (United States)

    Mapiye, Cletos; Aalhus, Jennifer L; Vahmani, Payam; Rolland, David C; McAllister, Timothy A; Block, Hushton C; Uttaro, Bethany; Proctor, Spencer D; Dugan, Michael E R

    2014-01-01

    Hamburger is the most consumed beef product in North America, but lacks in nutritional appeal due to its high fat content and high proportion of saturated fatty acids (SFA). Objectives of the present study were to improve the FA profiles of hamburgers made with perirenal fat (PRF) and subcutaneous fat (SCF) when feeding steers different diets along with examining differences in sensory attributes and oxidative stability. Diets included a control diet containing 70:30 red clover silage: barley based concentrate, a diet containing sunflower-seed (SS) substituted for barley, and diets containing SS with 15% wheat dried distillers' grain with solubles (DDGS-15) or 30% DDGS (DDGS-30). Hamburgers were made from triceps brachii and either PRF or SCF (80:20 w/w). Perirenal fat versus SCF hamburgers FA had 14.3% more (P 0.05), but feeding DDGS-30 diet reduced the proportions of (P fat depots offers an opportunity to differentially enhance beef hamburgers with 18:2n-6 biohydrogenation products (i.e., t11-18:1) with potential human health benefits without compromising their sensory attributes and oxidative stability during retail display.

  11. Inspector General, DoD, Oversight of the Army Audit Agency Audit of the FY 2000 Army Working Capital Fund Financial Statements

    National Research Council Canada - National Science Library

    2001-01-01

    Our objectives were to oversee the Army Audit Agency audit of the FY 2000 Department of the Army Working Capital Fund financial statements to verify whether we can rely on their work and to determine...

  12. Mercenaries in the Army of Hellenistic Athens

    Directory of Open Access Journals (Sweden)

    Igor V. Vostrikov

    2017-11-01

    Full Text Available This article interests in history of armed forces of the antiquity states, their structure, deployment order, the organization of command, evolution of arms, policy strokes, action of armies in the military conflicts, and to their use in internal political fight, as well as to involvement of mercenaries. During the Classical Period of Greek history big fame was gained by armed forces of Athens and Sparta. Athens in the 5th century BC was at the peak of power and pursued active foreign policy which was in many respects supported by powerful army and fleet. The reason of traditionally high interest in history of Athens of the Classical Period including the armed forces history of the polis also lies in it. However Athens and their armed forces suffered a serious loss and got beaten in the Peloponnese war and the final decline of political and military power of Athens occurred after defeat in Lamian war therefore military activity of the polis sharply decreases. Therefore the history of Hellenistic period Athens gets much less attention. Proceeding from it, the purpose of article consists in a research of the role of mercenaries in armed forces of Athens in the period of Hellenism. The leading method of this research is the comparative-historical method allowing tracking mercenaries hire by Athens during the specified period on the basis of a complex sources use. The main research results consist in identification of an order and features of the hired contingents use, their places in armed forces of the polis. Materials of article can be useful to the further scientific research regarding the history of Athens and military ancient history as well as to creating educational and handbooks on this perspective.

  13. Army Medical Department Leaders in Military Operations Other Than War

    National Research Council Canada - National Science Library

    Sadlon, Gary

    2000-01-01

    .... Likewise, the Army Medical Department (AMEDD) must insure its leaders, specifically those selected to deploy world-wide, have a more diverse skill set that enables them to fully operate within the full spectrum of scenarios...

  14. Resourcing Army Transformation: Solid Plan or House of Cards?

    National Research Council Canada - National Science Library

    Brimberry, Darrell

    2007-01-01

    .... We are also an army that is embarking on a monumental transformation effort. This ambitious plan to modernize and reorganize the force will take 30 plus years and over 210 billion dollars to complete...

  15. The Strategic Effect of Army Civilian Workplace Injuries and Illnesses

    National Research Council Canada - National Science Library

    Koucheravy, Richard J

    2008-01-01

    .... Lately, the Army has improved safety and embedded a more effective safety culture, but it has not improved its program for reducing civilian accident costs or returning injured workers to the workplace...

  16. Thinking Strategically About Army Strategic Leadership: Revolution or Evolution

    National Research Council Canada - National Science Library

    Boyce, Lisa

    2000-01-01

    The 1999 Senior Leadership Seminar held at George Mason University on 10 September 1999 brought together key senior Army leaders and civilian leadership experts from academia and industry to discuss...

  17. U.S. Army High Energy Laser (HEL) technology program

    Science.gov (United States)

    Lavan, Michael J.; Wachs, John J.

    2011-11-01

    The US Army is investing in Solid State Laser (SSL) technology to assess counter rocket, artillery, and mortar (C-RAM) and counter unmanned aerial vehicle (C-UAV) capabilities of solid state based HEL systems, as well as other potential applications for HELs of interest to the Army. The Army HEL program thrust areas are systematically moving the technology forward toward weaponization, including solid state laser technologies, advances in beam control technology, and conducting major demonstrations. The High Energy Laser Mobile Demonstrator (HELMD) will be a major step toward demonstrating HEL weapon capability to the soldier. The US Army will continue to pursue technologies that enable more compact systems compatible with, for example, a Stryker tactical vehicle as a crucial part of our strategy to provide a capability to the warfighter that can maneuver with the force.

  18. Integrating Language and Cultural Knowledge into the Army Officer Corps

    National Research Council Canada - National Science Library

    Purser, Jennifer L

    2008-01-01

    .... By promoting the acquisition of culture and language comprehension before individuals become commissioned, the Army can save both time and money in training officers to prepare for the COIN fight...

  19. The Army and the Endangered Species Act: Who's Endangering Whom?

    National Research Council Canada - National Science Library

    Diner, David N

    1993-01-01

    Mankind is causing a mass extinction of plant and animal species. The Army, as steward of 25 million acres of public lands, is being asked to play an increasingly decisive role in recovering endangered species...

  20. U.S. Army War College Key Strategic Issues List

    National Research Council Canada - National Science Library

    2008-01-01

    The Key Strategic Issues List (KSIL) offers military and civilian researchers a ready reference of topics that are of particular interest to the Department of the Army and the Department of Defense...

  1. Assessing Army Professional Forums Metrics for Effectiveness and Impact

    National Research Council Canada - National Science Library

    Cianciolo, Anna T; Heiden, Charles G; Prevou, Michael I

    2006-01-01

    .... Establishing such checks enhances the organizational impact of the initiative. The APF assessment framework developed in the present research enables the assessment of APFs during the early stages of the Army knowledge-management initiative.

  2. Branding: A Strategy for Manning an All-Volunteer Army

    National Research Council Canada - National Science Library

    Keeter, John M

    2008-01-01

    .... The ability to man the Army and realize the vision of a "quality" force is challenged not only by the impacts of a protracted war on the attitudes of the youth, and their influencers, but also...

  3. Military Personnel Strengths in the Army National Guard

    National Research Council Canada - National Science Library

    Stewart, Derek

    2002-01-01

    The accuracy of reported personnel strength and training participation rates has a direct impact on the reliability of the Army National Guard's budget and the allocation of funds to individual states...

  4. Determining Attributes Contributing to Success in Army Civil Schooling (ACS)

    National Research Council Canada - National Science Library

    Ottinger, Maurice A

    2006-01-01

    ...) in the Army and Defense Comptrollership Program Classes of 1998-2005 at Syracuse University which represent a specialized aspect of ACS where participants follow substantially the same program and earn the same degrees...

  5. The Army's Procurement and Conditional Acceptance of Medium Tactical Vehicles

    National Research Council Canada - National Science Library

    Jolliffe, Richard B; Burton, Bruce A; Meling, John E; Klein, Kevin W; Hoyt, James A; Harrigan, Celia J; Dismukes, Tracey E; Dameron, Roberta; Kwan, Michael Y; Sankhla, Chandra P; Milner, Jillisa H

    2007-01-01

    Who Should Read This Report and Why? Contracting officers and contract administrators should read this report because it discusses the Army's practices for conditional acceptance and first inspection acceptance of the vehicles. Background...

  6. Revolution in Business Affairs: Strategic Business Alliances in Army Transformation

    National Research Council Canada - National Science Library

    Bliss, Gary

    2002-01-01

    .... What commercial business practices could assist the Army in its Transformation? Can Strategic Business Alliances between the government and contractors help forge a winning team to aid in the Transformation effort?

  7. U.S. Army Medical Research Institute of Infectious Diseases

    Science.gov (United States)

    ... in the U.S. Army Medical Research Institute of Infectious Diseases (USAMRIID). The dedicated members of the USAMRIID staff ... military personnel and civilians from the threat of infectious diseases. We participate in support of emerging disease investigations, ...

  8. Qualitative and Quantitative Analysis for US Army Recruiting Input Allocation

    National Research Council Canada - National Science Library

    Brence, John

    2004-01-01

    .... An objective study of the quantitative and qualitative aspects of recruiting is necessary to meet the future needs of the Army, in light of strong possibilities of recruiting resource reduction...

  9. US Army Corps of Engineers Reachback Operations Center

    Data.gov (United States)

    Federal Laboratory Consortium — Providing Relevant Solutions to the Armed Forces and the NationThe USACE Reachback Operation Center at the U.S. Army Engineer Research and Development Center (ERDC)...

  10. Using Venture Capital to Improve Army Research and Development

    National Research Council Canada - National Science Library

    Held, Bruce

    2000-01-01

    ...) while keeping current equipment relevant and affordable. This issue paper introduces the idea that the Army should fund some of its technology development through a private venture capital organization...

  11. Army Facilities Management: A New Strategy for a New Environment

    Science.gov (United States)

    1990-01-01

    the private sector and the DoD. Army’s regulations and guidance governing facilities management are not in harmony with the DoD’s general policy of decentralizing as much responsibility and authority as possible.

  12. The Army's Future Combat Systems Program and Alternatives

    National Research Council Canada - National Science Library

    Lussier, Frances M

    2006-01-01

    .... To address concerns about the armored vehicle fleet's aging and the difficulties involved in transporting it as well as to equip the Army more suitably to conduct operations overseas on short notice...

  13. U.S. Army Recruiting: Problems and Fixes

    National Research Council Canada - National Science Library

    Jones, Reuben

    1999-01-01

    .... The real problem might rest with the Army's inability to develop a holistic accession strategy, to institute program modernization, to provide outstanding customer service, and to embrace change of outdated procedures...

  14. A Work Environment Climate Assessment of an Army Acquisition Center

    National Research Council Canada - National Science Library

    Doelling, Michael C; Kalapacs, Jenni J

    2005-01-01

    .... The goal of this Joint Applied Project was to identify organizational climate characteristics of the Army Acquisition Center to provide supervisors with data on the extent to which employees perceive...

  15. U.S. Army War College Guide to Strategy

    National Research Council Canada - National Science Library

    Cerami, Joseph

    2001-01-01

    For more than 3 decades, the Army War College Department of National Security and Strategy has faced the challenge of educating future strategic leaders on the subject of national security, or grand strategy...

  16. Army Transformation and Digitization - Training and Resource Challenges

    National Research Council Canada - National Science Library

    Ferrell, Robert

    2002-01-01

    .... A changing world order, diminishing resources and rapid and continuous advances in technology are the driving forces behind the Army's transformation campaign and the redesign of the force to the Force XXI concept...

  17. Power and Energy Architecture for Army Advanced Energy Initiative

    National Research Council Canada - National Science Library

    Shaffer, Edward C; Massie, Darrell D; Cross, James B

    2006-01-01

    ... technologies for the Army. The current P&E architecture is an amalgam of independent programs, which traditionally have been developed in stovepipe organizations, and often as an afterthought to the development of other advanced technologies...

  18. An Overdue Post-Cold War Army Structure

    National Research Council Canada - National Science Library

    Dixon, Michael

    2004-01-01

    ...). The Army has rapidly aligned itself with the Department of Defense (DoD) Transformation plan and is aggressively identifying and building required capabilities now in support of the Global War on Terrrorism (GWOT...

  19. The system development of consequence analysis for army nuclear accident

    International Nuclear Information System (INIS)

    Yuan Wei; Zuo Li; Chen Xianbo; Qu Yantao; Yang Hongwei

    2014-01-01

    Through the analysis of the assessment technique and the function characteristics of related system, domestic nuclear facilities accident consequence, assessment technique for army nuclear accident consequence was studied and the difference between the two evaluation methods were also compared. On this basis, the function, the application and the optimization of a software system that was developed for army was discussed. All of these will provide suggestion for the nuclear weapon accident consequence assessment. (authors)

  20. Army Logistician. Volume 36, Issue 6, November-December 2004

    Science.gov (United States)

    2004-12-01

    soldier, an Army or D efense civilian, or a contra ctor—you need not only to stay abreast of what is happening in Army and Defense logistics but also...movement would hit even stronger defenses than the ones currently to their front—which happened with the defenses of Rich- mond, Virginia, and Atlanta... Pocahontas , Iowa. TDA Unit (Large). Area Maintenance Support Activity 57 (Ground), Belton, Missouri. MTOE Company Without Property Book. 216th