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Sample records for wilson lecture natural

  1. Research of CO2 concentration in naturally ventilated lecture room

    Science.gov (United States)

    Laska, Marta; Dudkiewicz, Edyta

    2017-11-01

    Naturally ventilated buildings especially dedicated for educational purposes need to be design to achieve required level of thermal comfort and indoor air quality. It is crucial in terms of both: health and productivity of the room users. Higher requirements of indoor environment are important due to the level of students concentration, their ability to acquire new knowledge and willingness to interact with the lecturer. The article presents the results of experimental study and surveys undertaken in naturally ventilated lecture room. The data is analysed in terms of CO2 concentration and its possible influence on users. Furthermore the outcome of the research is compared with the CO2 concentration models available in the literature.

  2. Applying natural evolution for solving computational problems - Lecture 2

    CERN Multimedia

    CERN. Geneva

    2017-01-01

    Darwin’s natural evolution theory has inspired computer scientists for solving computational problems. In a similar way to how humans and animals have evolved along millions of years, computational problems can be solved by evolving a population of solutions through generations until a good solution is found. In the first lecture, the fundaments of evolutionary computing (EC) will be described, covering the different phases that the evolutionary process implies. ECJ, a framework for researching in such field, will be also explained. In the second lecture, genetic programming (GP) will be covered. GP is a sub-field of EC where solutions are actual computational programs represented by trees. Bloat control and distributed evaluation will be introduced.

  3. Applying natural evolution for solving computational problems - Lecture 1

    CERN Multimedia

    CERN. Geneva

    2017-01-01

    Darwin’s natural evolution theory has inspired computer scientists for solving computational problems. In a similar way to how humans and animals have evolved along millions of years, computational problems can be solved by evolving a population of solutions through generations until a good solution is found. In the first lecture, the fundaments of evolutionary computing (EC) will be described, covering the different phases that the evolutionary process implies. ECJ, a framework for researching in such field, will be also explained. In the second lecture, genetic programming (GP) will be covered. GP is a sub-field of EC where solutions are actual computational programs represented by trees. Bloat control and distributed evaluation will be introduced.

  4. Wilson Disease

    Science.gov (United States)

    Wilson disease is a rare inherited disorder that prevents your body from getting rid of extra copper. You need ... copper into bile, a digestive fluid. With Wilson disease, the copper builds up in your liver, and ...

  5. Wilson Disease

    Science.gov (United States)

    ... Liver Foundation March of Dimes National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) Wilson Disease Association See all related organizations Publications Order NINDS Publications Definition Wilson disease (WD) is a rare inherited disorder ...

  6. Wilson disease

    Science.gov (United States)

    ... nervous system and peripheral nervous system Copper urine test References Cox DW, Roberts EA. Wilson disease. In: Feldman M, Friedman LS, Brandt LJ, eds. Sleisenger and Fordtran's Gastrointestinal ...

  7. Man and SuperNature. Lecture 12, September 27, 1946

    Science.gov (United States)

    Montessori, Maria

    2015-01-01

    "Man and SuperNature" is a lyrical chapter in the 1946 London course following the emergence of Cosmic Education in Kodaikanal, India. Montessori contrasts the adaptation required of animals for their survival to conscious human adaptation. Animals exist and adapt to nature, but man can alter nature and change the environment.…

  8. [Wilson's disease

    OpenAIRE

    Duclos-Vallée, Jean-Charles; Ichaï, Philippe; Chapuis, Philippe; Misrahi, Micheline; Woimant, France

    2006-01-01

    http://www.huveaux.fr/fr_santesite.asp; Wilson's disease is an autosomal recessive disorder of copper excess. This illness results from mutations of the ATP7B gene chromosome 13. The discovery of the gene allowed a better understanding of cytosolic copper trafficking its relationship with ceruloplasmin synthesis. Symptomatic patients may present with hepatic, neurologic or psychiatric forms. Clinical and phenotypic evidences provide only presumptive arguments for this disease which can be rou...

  9. The CUREA Program at Mount Wilson

    Science.gov (United States)

    Turner, Paula C.; LoPresto, J. C.; Simmons, M.

    2006-12-01

    For fifteen years, Mount Wilson Observatory has been host to a unique educational program designed to introduce undergraduate students of physics and astronomy to elements of observational solar and stellar astrophysics. Founded by faculty members from four-year colleges who dubbed themselves the Consortium for Undergraduate Research and Education in Astronomy (CUREA), the CUREA program is an intensive two-week course in observational astronomy. It includes lectures by astronomers and physicists, observational exercises in both solar and stellar astrophysics, tours of various research facilities on the mountain and in the Los Angeles area, and an observational mini-project designed and executed by each student during the second week of the program. This paper will present the program’s curriculum and goals, a brief history, and examples of observational projects undertaken by recent participants. CUREA is administered by the Mount Wilson Observatory Association, using facilities provided by the Mount Wilson Institute.

  10. The 1999 Lauriston S. Taylor lecture--back to background: natural radiation and radioactivity exposed.

    Science.gov (United States)

    Harley, N H

    2000-08-01

    I am profoundly grateful for being chosen as the twenty-third presenter of the Lauriston S. Taylor Lecture, and I share this honor with a list of distinguished scientists, including my husband, who pay tribute to the premier leader in radiation protection. In 1938, Laurie was working for the National Bureau of Standards and chaired the Advisory Committee on X-ray and Radium Protection, a group of 8 persons, who set the pace for all forthcoming radiation standards. NBS had, since 1913, been standardizing essentially all of the radium offered for sale in the U.S., and the problem arose to revise the handbook on proper conditions for handling radium based on the then current knowledge. This resulted in Handbook 23 (1938) superseding the 1934 work. At the time Laurie was a scientist working in the measurements side of radiation and though he contributed much to that field, his name is inseparably linked with guidance in radiation protection. Today we pay tribute for his leadership that he carried out with intelligence, grace, and personal warmth. My talk today deals mostly with measured data for naturally occurring internal radiation emitters and how these data can be used for predictive purposes in estimating the dose and risk from internal body contamination. This stresses the "and Measurements" part of the Council's title. The topic of this year's NCRP Annual Meeting is "Radiation Protection in Medicine: Contemporary Issues." I believe that physicians and State and Federal agencies will have to cope with complaints following various exposure situations resulting from the cleanup of background radionuclides during closure at nuclear facilities, military use of radioactivity, and occurrences of high natural background in some locations. They will find comfort in the knowledge that existing background radiation data can be the basis for predictions of realistic dose and risk in most situations.

  11. Wilson's disease: current status.

    Science.gov (United States)

    Yarze, J C; Martin, P; Muñoz, S J; Friedman, L S

    1992-06-01

    To review current concepts about the pathogenesis, clinical manifestations, and treatment of Wilson's disease, with an emphasis on recent developments. Published information was identified using MEDLINE and through extensive manual searching of bibliographies in identified sources. The basic biochemical alteration responsible for deranged hepatobiliary copper homeostasis in Wilson's disease has yet to be identified. The gene for Wilson's disease has been mapped to chromosome 13, but the function of its gene product has not yet been determined. The clinical manifestations of Wilson's disease are varied and often nonspecific and include a range of hepatic, neurologic, and psychiatric findings. Penicillamine remains the drug of choice for the treatment of Wilson's disease, but recent experience suggests that trientine and zinc may be safe, effective alternatives. All three drugs are probably safe for use in pregnant patients with Wilson's disease. Liver transplantation is the only effective treatment for Wilsonian fulminant hepatic failure and corrects the underlying metabolic defect. Wilson's disease is a disorder of hepatobiliary copper excretion manifested predominantly by hepatic and neurologic copper toxicosis and inherited in an autosomal recessive pattern. Although the specific underlying biochemical defect remains to be defined, specific therapy is available and usually successful. Maintaining a high index of suspicion is critical in diagnosing this readily treatable inherited disease.

  12. Askey-Wilson polynomial

    NARCIS (Netherlands)

    Koornwinder, T.H.

    2012-01-01

    Askey-Wilson polynomial refers to a four-parameter family of q-hypergeometric orthogonal polynomials which contains all families of classical orthogonal polynomials (in the wide sense) as special or limit cases.

  13. Wilson's Disease Association International

    Science.gov (United States)

    ... Back WDA Membership Latest News & Announcements Wilson's Warriors Events Back The Big WOW 2017 Annual Conference WDA Publications Back Downloads Corporate Sponsorship Forms Membership Forms Resources The Big WOW Newsletters ...

  14. Lecturing the lecturers

    Science.gov (United States)

    Osborne, Jonathan

    2010-02-01

    João Magueijo's article "Cargo-cult training" about the failings of compulsory educational training for lecturers (December 2009 pp16-17) is an illustration of why some university lecturers do need to be educated about education. His argument that we should use lectures because students like them ignores the large body of educational research stating that this is the least effective form of education. It might, as the well-known aphorism states, be a successful means of transferring the notes of the lecturer to the notes of the students without going through the minds of either, but the evidence shows that only 10% of students learn material in this way. Rather, all the educational literature points to the fact that interactive, discursive methods are much more likely to produce learning with understanding.

  15. Woodrow Wilson on Education

    Science.gov (United States)

    Berlin, Isaiah

    2012-01-01

    In this 1960 article Isaiah Berlin compares Woodrow Wilson's emphasis on the need to educate university students for life in the real world with the difference between Oxford "realism" and Cambridge "idealism" in the nineteenth century. Oxford favoured a Wilsonian preference for general education over (but not to the exclusion of) pure…

  16. Wilson Fermions with Four Fermion Interactions

    DEFF Research Database (Denmark)

    Rantaharju, Jarno; Drach, Vincent; Hietanen, Ari

    2015-01-01

    We present a lattice study of a four fermion theory, known as Nambu Jona-Lasinio (NJL) theory, via Wilson fermions. Four fermion interactions naturally occur in several extensions of the Standard Model as a low energy parameterisation of a more fundamental theory. In models of dynamical electrowe...

  17. ACADEMIC TRAINING LECTURE

    CERN Multimedia

    Academic Training; Tel. 73127

    2001-01-01

    ACADEMIC TRAINING LECTURE 1, 2, 3, 4 and 5 October LECTURES FOR POSTGRADUATE STUDENTS From 10:00 hrs - Main Auditorium bldg. 500 1 Introduction to particle accelerators E.J.N. Wilson / CERN-AC , Head of the CERN Accelerator School This new series of lectures is intended for anyone with a technical or scientific background who would like to become familiar with the principles of accelerator design. It is a complement to last year's course and includes new lectures on present day accelerators, and their applications as well as colliders and neutrino factories. Beam dynamics, which was treated at length in last year's course, has been compressed into one lecture, intended as revision for those who followed earlier courses and an introduction for newcomers to the field. The course should not be missed by those who will attend the CAS Intermediate Accelerator School in Seville. 1-10 10:00 Present-day Accelerators 11:00 - Beam Dynamics 2-10 10:00 Accelerating Cavities 11:00 - Non-linear Dynamics 3-10 10:00 E...

  18. Kenneth Wilson and lattice QCD

    CERN Document Server

    Ukawa, Akira

    2015-01-01

    We discuss the physics and computation of lattice QCD, a space-time lattice formulation of quantum chromodynamics, and Kenneth Wilson's seminal role in its development. We start with the fundamental issue of confinement of quarks in the theory of the strong interactions, and discuss how lattice QCD provides a framework for understanding this phenomenon. A conceptual issue with lattice QCD is a conflict of space-time lattice with chiral symmetry of quarks. We discuss how this problem is resolved. Since lattice QCD is a non-linear quantum dynamical system with infinite degrees of freedom, quantities which are analytically calculable are limited. On the other hand, it provides an ideal case of massively parallel numerical computations. We review the long and distinguished history of parallel-architecture supercomputers designed and built for lattice QCD. We discuss algorithmic developments, in particular the difficulties posed by the fermionic nature of quarks, and their resolution. The triad of efforts toward b...

  19. Mowat-Wilson syndrome

    DEFF Research Database (Denmark)

    Engenheiro, E; Møller, R S; Pinto, M

    2008-01-01

    Mowat-Wilson syndrome (MWS) is an autosomal dominant developmental disorder with mental retardation and variable multiple congenital abnormalities due to mutations of the ZEB2 (ZFHX1B) gene at 2q22. MWS was first described in 1998 and the causative gene was delineated in 2001. Since then, 115...... different mutations of ZEB2 have been published in association with this syndrome in 161 individuals. However, recent reports suggest that due to the variability of the congenital abnormalities, this syndrome may still be underdiagnosed. We report two unrelated patients with MWS where the clinical diagnosis...

  20. ACADEMIC TRAINING LECTURE

    CERN Multimedia

    Academic Training; Tel. 73127

    2001-01-01

    1, 2, 3, 4 and 5 October LECTURES FOR POSTGRADUATE STUDENTS From 10:00 hrs - Main Auditorium bldg. 500 1 Introduction to particle accelerators E.J.N. Wilson / CERN-AC , Head of the CERN Accelerator School This new series of lectures is intended for anyone with a technical or scientific background who would like to become familiar with the principles of accelerator design. It is a complement to last year's course and includes new lectures on present day accelerators, and their applications as well as colliders and neutrino factories. Beam dynamics, which was treated at length in last year's course, has been compressed into one lecture, intended as revision for those who followed earlier courses and an introduction for newcomers to the field. The course should not be missed by those who will attend the CAS Intermediate Accelerator School in Seville. 1-10 10:00 Present-day Accelerators 11:00 - Beam Dynamics 2-10 10:00 Accelerating Cavities 11:00 - Non-linear Dynamics 3-10 10:00 Electron Dynamics 11:00 - ...

  1. Wilson loops as precursors

    Energy Technology Data Exchange (ETDEWEB)

    Susskind, Leonard [Department of Physics, Stanford University, Stanford, California 94305-4060 (United States); Toumbas, Nicolaos [Department of Physics, Stanford University, Stanford, California 94305-4060 (United States)

    2000-02-15

    There is substantial evidence that string theory on AdS{sub 5}xS{sub 5} is a holographic theory in which the number of degrees of freedom scales as the area of the boundary in Planck units. Precisely how the theory can describe bulk physics using only surface degrees of freedom is not well understood. A particularly paradoxical situation involves an event deep in the interior of the bulk space. The event must be recorded in the (Schroedinger picture) state vector of the boundary theory long before a signal, such as a gravitational wave, can propagate from the event to the boundary. In a previous paper with Polchinski, we argued that the ''precursor'' operators which carry information stored in the wave during the time when it vanishes in a neighborhood of the boundary are necessarily non-local. In this paper we argue that the precursors cannot be products of local gauge invariant operators such as the energy momentum tensor. In fact gauge theories have a class of intrinsically non-local operators which cannot be built from local gauge invariant objects. These are the Wilson loops. We show that the precursors can be identified with Wilson loops whose spatial size is dictated by the UV-IR connection. (c) 2000 The American Physical Society.

  2. [Jacqueline Wilson. Tracy Beakeri sari] / Krista Kivisalu

    Index Scriptorium Estoniae

    Kivisalu, Krista, 1968-

    2016-01-01

    Tutvustus: Wilson, Jacqueline. Tracy Beakeri lugu. [Tallinn] : Pegasus, 2015 ; Wilson, Jacqueline. Pühadeüllatus. [Tallinn] : Pegasus, c2015 ; Wilson, Jacqueline. Julgusmäng. [Tallinn] : Pegasus, c2015

  3. Wilson's disease and hemochromatosis.

    Science.gov (United States)

    Neimark, Ezequiel; Schilsky, Michael L; Shneider, Benjamin L

    2004-02-01

    Wilson's disease (WD) and hereditary hemochromatosis (HH) are two inherited disorders with potentially devastating and life-threatening complications. Their eminent treatability makes diagnosis in adolescence or young adulthood critical. WD is the result of abnormal copper homeostasis, causing copper overload and end-organ damage. Chelation therapy can be highly efficacious in preventing manifestations of WD. HH is caused by inappropriate absorption of dietary iron, typically as the result of a specific mutation, C282Y, in the HFE gene. End-organ disease from iron accumulation is protean and includes progressive damage of the liver, pancreas, skin, heart, and pituitary. It is important to permit therapeutic phlebotomy to commence before the onset of complications.

  4. Marine natural hazards in coastal zone: observations, analysis and modelling (Plinius Medal Lecture)

    Science.gov (United States)

    Didenkulova, Ira

    2010-05-01

    Giant surface waves approaching the coast frequently cause extensive coastal flooding, destruction of coastal constructions and loss of lives. Such waves can be generated by various phenomena: strong storms and cyclones, underwater earthquakes, high-speed ferries, aerial and submarine landslides. The most famous examples of such events are the catastrophic tsunami in the Indian Ocean, which occurred on 26 December 2004 and hurricane Katrina (28 August 2005) in the Atlantic Ocean. The huge storm in the Baltic Sea on 9 January 2005, which produced unexpectedly long waves in many areas of the Baltic Sea and the influence of unusually high surge created by long waves from high-speed ferries, should also be mentioned as examples of regional marine natural hazards connected with extensive runup of certain types of waves. The processes of wave shoaling and runup for all these different marine natural hazards (tsunami, coastal freak waves, ship waves) are studied based on rigorous solutions of nonlinear shallow-water theory. The key and novel results presented here are: i) parameterization of basic formulas for extreme runup characteristics for bell-shape waves, showing that they weakly depend on the initial wave shape, which is usually unknown in real sea conditions; ii) runup analysis of periodic asymmetric waves with a steep front, as such waves are penetrating inland over large distances and with larger velocities than symmetric waves; iii) statistical analysis of irregular wave runup demonstrating that wave nonlinearity nearshore does not influence on the probability distribution of the velocity of the moving shoreline and its moments, and influences on the vertical displacement of the moving shoreline (runup). Wave runup on convex beaches and in narrow bays, which allow abnormal wave amplification is also discussed. Described analytical results are used for explanation of observed extreme runup of tsunami, freak (sneaker) waves and ship waves on different coasts

  5. Effects of fluids on rock deformation and fault slip: From nature to societal impact (Louis Néel Medal Lecture)

    Science.gov (United States)

    Spiers, Christopher J.

    2017-04-01

    Understanding the effects of fluid-rock interaction on rock and fault mechanical behaviour is central not only to understanding natural tectonic and seismogenic processes, and phenomena such as resource trapping, but also to evaluating the impact of industrial operations in the Earth's crust. These include activities ranging from extraction of geo-energy to geological storage of fuels, CO2 and wastes. For the assessment of both natural and induced geohazards, a physics-based approach to quantifying rock mechanical behaviour is unmissable. Microstructural studies of rocks deformed naturally in the mid and upper crust, or at seismogenic depths in subduction zones, show widespread evidence for brittle deformation (cataclasis), dissolution-precipitation transfer, fluid-related reactions producing weak minerals, and dilatation/cementation of fractures, cracks and pores. In addition, experimental work on rocks and simulated fault gouges has shown that the presence of water strongly influences their mechanical and transport properties. This implies the operation of fluid-assisted deformation mechanisms, such as stress corrosion cracking and diffusive mass transfer (pressure solution). More recently, other fluid-coupled deformation processes have been recognised, in rocks from peridotites and granites to sandstones, limestones and shales. In this lecture, I will give an overview of progress in this area. I will address the physics of pressure solution and stress corrosion cracking and how they contribute to the deformation and compaction of sandstone, carbonate and evaporite rocks in the mid and upper crust, under natural conditions and in the context of deformation caused by geo-resources production and geo-storage. New results on how these processes are affected by pore fluid salinity, gas content and CO2 activity will also be considered, as will data on the effects of mineral-fluid reactions and associated volume changes on rock deformation, fracturing and transport

  6. Treatment of Wilson's disease.

    Science.gov (United States)

    Jabłońska-Kaszewska, Irena; Dabrowska, Ewa; Drobińska Jurowiecka, Anna; Falkiewicz, Bogdan

    2003-08-01

    On the basis of literature review and own experience we presented the method of treatment of Wilson's disease. Causative treatment has been impossible so far, although gene therapy could be real in the future. Nowadays the principle of treatment is the elimination of the excess of easily mobilized copper by chelating agents or blocking the intestinal absorption of copper. Chelation therapy, aimed at mobilizing copper from the affected organs and promoting its excretion in the urine or stool is the most important. The major chelating agent is d-penicillamine, which is quite effective but not without some side effects. Alternative chelating agents such as trientine and tetrathiomolybdate have also been successfully employed. Zinc salts are also of therapeutic value. They promote copper excretion by inducing the synthesis of metallothionein in the intestine, thereby blocking copper absorption from the gut. Zinc salts have almost no side effects. They cannot be used as an initial treatment, but are very effective for maintenance therapy. The chelation therapy is ineffective in patients with acute liver failure with encephalopathy and hemolysis. In these cases, liver transplantation is the only hope for survival. Liver transplantations in patients with dominating psychoneurological symptoms are open to discussion.

  7. Wilson Disease: Case Report

    Directory of Open Access Journals (Sweden)

    Esra Tuğ

    2007-01-01

    Full Text Available Wilson Disease (WD is an autosomal recessive hereditary disease of human copper metabolism, which causes hepatic and neuropsychiatric diseases. Estimated prevalence is 1: 30.000. In WD, ATP7B gene located on chromosome 13 (13q14.3-q21.1, coding the protein for hepatic copper transport and, having an important role in copper metabolism has been affected. Clinical findings in WD are complex and, neurological symptoms such as tremor, disartria and psychiatric disorders, acute liver deficiency, chronic hepatit or cirrhosis may develop. For the last year, 27 years old female patient observed in other medical centre owing to benign positional vertigo applied to our department. Her sister and brother have been diagnosed as WD. No peripheral syptoms of hepatic disease or hepatosplenomegaly existed in our patient. Neurological examination was normal to except for positional tremor. Because our patient had rare clinical features for WD and bad prognosis, presented by us to emphasize necessity of the researched of the most frequent mutations seen in Turkiye.

  8. Genetics Home Reference: Wilson disease

    Science.gov (United States)

    ... 482-93. Review. Citation on PubMed Ferenci P. Pathophysiology and clinical features of Wilson disease. Metab Brain ... newborn screening? New Pages MDA5 deficiency type 2 diabetes mitochondrial complex I deficiency All New & Updated Pages ...

  9. How Is Wilson Disease Inherited?

    Science.gov (United States)

    ... Back WDA Membership Latest News & Announcements Wilson's Warriors Events Back The Big WOW 2017 Annual Conference WDA Publications Back Downloads Corporate Sponsorship Forms Membership Forms Resources The Big WOW Newsletters ...

  10. How Is Wilson Disease Diagnosed?

    Science.gov (United States)

    ... Back WDA Membership Latest News & Announcements Wilson's Warriors Events Back The Big WOW 2017 Annual Conference WDA Publications Back Downloads Corporate Sponsorship Forms Membership Forms Resources The Big WOW Newsletters ...

  11. [Therapy of Wilson disease].

    Science.gov (United States)

    Smolarek, C; Stremmel, W

    1999-04-01

    Wilson disease is a copper storage disease with autosomal-recessive trait that is predominantly a disorder of the adolescent and young adult. Clinical manifestations are dominated by hepatic and/or neurological symptoms. Diagnostic procedures include determination of total serum copper, free serum copper and serum ceruloplamin concentrations as well as urinary copper excretion. Confirmation of diagnosis may be achieved by liver biopsy and histological determination of copper content. The aim of treatment is reduction of tissue copper concentration and detoxification of copper. Drugs applied are the chelating agents. D-penicillamine and trientine, or zinc. The chelating agents induce renal and biliary copper excretion and increased synthesis of metallothionein, which attaches and detoxifies intracellular copper, leading to impaired absorption and binding of excess intracellular copper. Treatment with zinc results in induction of hepatic and intestinal metallothionein synthesis. Regular examinations of the parameters of copper metabolism are necessary in order to control the therapeutic effect. Free copper serum concentrations and urinary copper excretion should reach values below 10 micrograms/dl and 80 micrograms/day, respectively. A significant improvement of clinical symptoms and normalization of parameters of copper metabolism can be expected earliest six months after onset of therapy. Anti-copper treatment may be accompanied by copper-reduced diet. Lifelong therapy is required and provides life-expectancy near to normal. Interruption of treatment leads to reaccumulation of copper, often resulting in fulminant hepatic failure. This can also be observed as initial presentation in 5% of cases (predominant age 12 to 25 years). End stage liver disease and fulminant hepatic failure are indications for liver transplantation by which the genetic defect is phenotypically cured. Here decoppering treatment is no longer required. Whether severe neurological disorders may

  12. [Natural or interactive kinds? The transient mental disorders in Ian Hacking's lectures at the Collège de France (2000-2006)].

    Science.gov (United States)

    Delille, Emmanuel; Kirsch, Marc

    2016-12-01

    The concepts developed by Ian Hacking during his lectures at the Collège de France (2000-2006) have provided an important contribution to the debates within the field of philosophy of psychiatry. Professor at the Chair of Philosophy and History of Scientific Concepts after Michel Foucault, Hacking is the author of a reflection on the classification of mental disorders, which arises from the problem of the natural kinds. In order to explain the case studies developed in Hacking's Paris lectures, we first go back to the definition of a series of concepts, then we discuss the status of his scientific metaphors. Finally we analyze the relationship between the notions, respectively, of "transient mental illness" and "culture-bound syndrome". We emphasize that the latter derives from the Canadian transcultural psychiatry.

  13. Sextet Model with Wilson Fermions

    DEFF Research Database (Denmark)

    Hansen, Martin; Pica, Claudio

    2017-01-01

    We present new results from our ongoing study of the SU(3) sextet model with two flavors in the two-index symmetric representation of the gauge group. In the simulations use unimproved Wilson fermions to investigate the infrared properties of the model. We have previously presented results for th...

  14. G. Terence Wilson: Award for Distinguished Scientific Applications of Psychology.

    Science.gov (United States)

    2014-11-01

    The APA Award for Distinguished Scientific Applications of Psychology is presented to a person who, in the opinion of the Committee on Scientific Awards, has made distinguished theoretical or empirical advances leading to the understanding or amelioration of important practical problems. The 2014 recipient is G. Terence Wilson, who received the award for "his outstanding contributions to the nature and theory of behavior therapy." Wilson's award citation, biography, and a selected bibliography are presented here. PsycINFO Database Record (c) 2014 APA, all rights reserved.

  15. Nambu-Jona-Lasinio model with Wilson fermions

    DEFF Research Database (Denmark)

    Rantaharju, Jarno; Drach, Vincent; Pica, Claudio

    2017-01-01

    We present a lattice study of a Nambu-Jona-Lasinio (NJL) model using Wilson fermions. Four-fermion interactions are a natural part of several extensions of the Standard Model, appearing as a low-energy description of a more fundamental theory. In models of dynamical electroweak symmetry breaking ...

  16. Rodin, Patton, Edison, Wilson, Einstein: Were They Really Learning Disabled?

    Science.gov (United States)

    Adelman, Kimberly A.; Adelman, Howard S.

    1987-01-01

    The practice of posthumously diagnosing historical figures is discussed. Emphasis is on the unsatisfactory nature of evidence found for those diagnosed as learning-disabled or dyslexic and the possibility of other explanations for identified problems. Posthumous diagnoses of Auguste Rodin, George Patton, Thomas Edison, Woodrow Wilson, and Albert…

  17. Online lectures.

    Science.gov (United States)

    Wink, Diane M

    2010-01-01

    In this bimonthly series, the author examines how nurse educators can use Internet and Web-based computer technologies such as search, communication, and collaborative writing tools; social networking and social bookmarking sites; virtual worlds; and Web-based teaching and learning programs. This article describes the creation of lectures that can be embedded in Web-based courses and presentations.

  18. Wilson lines in quantum field theory

    CERN Document Server

    Cherednikov, Igor O; Veken, Frederik F van der

    2014-01-01

    The objective of this book is to get the reader acquainted with theoretical and mathematical foundations of the concept of Wilson loops in the context of modern quantum field theory. It teaches how to perform independently with some elementary calculations on Wilson lines, and shows the recent development of the subject in different important areas of research.

  19. The link between copper and Wilson's disease.

    Science.gov (United States)

    Purchase, Rupert

    2013-01-01

    Wilson's disease (hepatolenticular degeneration) is a rare inherited autosomal recessive disorder of copper metabolism leading to copper accumulation in the liver and extrahepatic organs such as the brain and cornea. Patients may present with combinations of hepatic, neurological and psychiatric symptoms. Copper is the therapeutic target for the treatment of Wilson's disease. But how did copper come to be linked with Wilson's disease? The answer encompasses a study of enzootic neonatal ataxia in lambs in the 1930s, the copper-chelating properties of British Anti-Lewisite, and the chemical analysis for copper of the organs of deceased Wilson's disease patients in the mid-to-late 1940s. Wilson's disease is one of a number of copper-related disorders where loss of copper homeostasis as a result of genetic, nutritional or environmental factors affects human health.

  20. Cognitive impairment in Wilson's disease

    Directory of Open Access Journals (Sweden)

    Norberto Anizio Ferreira Frota

    Full Text Available Abstract Wilson's disease (WD or hepatolenticular degeneration is a rare, genetic and systemic disease, caused by a deficit in the metabolism of copper, leading to its accumulation in different organs, mainly the liver, followed by the central nervous system, especially the basal ganglia. When symptoms begin between the second and third decades of life, approximately 50% of the patients show neurological symptoms. Although dystonia and dysarthria are the most common neurological signs, cognitive changes have been reported since the first cases were described in 1912. Memory change is one of the most common impairments, but other cognitive changes have been reported, including dementia in untreated cases. In this article we review the cognitive changes in WD patients and the occurrence of dementia.

  1. ACADEMIC TRAINING LECTURE

    CERN Multimedia

    Academic Training; Tel. 73127

    2001-01-01

    23, 24, 25, 26 and 27 April REGULAR LECTURE PROGRAMME From 11:00 hrs - Main Auditorium bldg. 500, on 23 April from 11:15 to 12:15 hrs Searches for Dark Matter F. Feinstein / CPPM, Marseille, F The fact that the mass of the visible stars could not account for the gravitational cohesion of the galaxy clusters was the first manifestation of non-radiating matter in the Universe. Since then, many observations imply that most of the matter is indeed dark. Its nature is still unknown and likely to have several contributions. Recent results indicate that most of it may not be composed of normal matter. These lectures will review the experimental methods, which have been developed to unravel this 70-year long mystery and confront their results with the current theoretical framework of cosmology.

  2. Wilson's disease and other neurological copper disorders.

    Science.gov (United States)

    Bandmann, Oliver; Weiss, Karl Heinz; Kaler, Stephen G

    2015-01-01

    The copper metabolism disorder Wilson's disease was first defined in 1912. Wilson's disease can present with hepatic and neurological deficits, including dystonia and parkinsonism. Early-onset presentations in infancy and late-onset manifestations in adults older than 70 years of age are now well recognised. Direct genetic testing for ATP7B mutations are increasingly available to confirm the clinical diagnosis of Wilson's disease, and results from biochemical and genetic prevalence studies suggest that Wilson's disease might be much more common than previously estimated. Early diagnosis of Wilson's disease is crucial to ensure that patients can be started on adequate treatment, but uncertainty remains about the best possible choice of medication. Furthermore, Wilson's disease needs to be differentiated from other conditions that also present clinically with hepatolenticular degeneration or share biochemical abnormalities with Wilson's disease, such as reduced serum ceruloplasmin concentrations. Disordered copper metabolism is also associated with other neurological conditions, including a subtype of axonal neuropathy due to ATP7A mutations and the late-onset neurodegenerative disorders Alzheimer's disease and Parkinson's disease. Copyright © 2015 Elsevier Ltd. All rights reserved.

  3. Geographic variations in Wilson's disease.

    Science.gov (United States)

    Chu, N S; Hung, T P

    1993-07-01

    Certain features of Wilson's disease (WD) in Asia have been found to be different from those in other continents. The higher prevalence rate in Japan is presumably due to a higher consanguinity rate. In Chinese there is a tight linkage between WD and two gene loci for esterase D and retinoblastoma in the long arm of chromosome 13. The high proportion of patients with hepatic presentation accounts for early onset of WD in the Japanese and Chinese series. Skeletal involvement, leg hyperpigmentation, dark complexion, amenorrhea, epileptic seizures, and cerebral white matter degeneration are relatively more common among WD patients in Asia. Excessive copper in the liver appears to have a protective effect against hepatocellular carcinoma and type B hepatitis. Electrophysiological studies suggest widespread functional disturbances of the CNS in WD. Side-effects from penicillamine are rather frequent and often lead to interruption of the therapy. Trien is found to be effective without adverse reactions. Oral zinc therapy may be a suitable alternative for long-term management of WD patients in developing Asian countries.

  4. Animal models of Wilson disease.

    Science.gov (United States)

    Medici, Valentina; Huster, Dominik

    2017-01-01

    Wilson disease (WD) is caused by ATPase copper-transporting beta (ATP7B) mutations and results in copper toxicity in liver and brain. Although the defective gene was identified in 1993, the specific mechanisms underlying copper toxicity and the remarkable phenotypic diversity of the disease are still poorly understood. Animal models harboring defects in the ATP7B homolog have helped to reveal new insights into pathomechanisms of WD. Four rodent models with ATP7B gene defects have been described - the Long-Evans Cinnamon (LEC) rat, inbred mouse models (toxic milk (tx), the Jackson Laboratory toxic milk (tx-j)), and the genetically engineered ATP7B(-/-) (knockout) mouse - all of which develop liver disease to different extents. Copper accumulation in parts of the brain accompanied by some neurologic involvement was revealed in LEC rats and tx/tx-j mice, but the pathology is less severe than human neurologic WD. Several dogs show hepatic copper toxicity resembling WD; however, brain involvement has not been observed and the underlying genetic defect is different. These models are of great value for examination of copper distribution and metabolism, gene expression, and investigation of liver and brain pathology. The availability of disease models is essential for therapeutic interventions such as drug, gene, and cell therapy. Findings made by animal studies may facilitate the development of specific therapies to ameliorate WD progression. © 2017 Elsevier B.V. All rights reserved.

  5. Liver transplantation for Wilson disease

    Science.gov (United States)

    Catana, Andreea M; Medici, Valentina

    2012-01-01

    The aim of this paper is to review the current status of liver transplantation (LT) for Wilson disease (WD), focusing on indications and controversies, especially in patients with neuropsychiatric disease, and on identification of acute liver failure (ALF) cases related to WD. LT remains the treatment of choice for patients with ALF, as initial presentation of WD or when anti-copper agents are stopped, and for patients with chronic liver disease progressed to cirrhosis, unresponsive to chelating medications or not timely treated with copper chelating agents. The indication for LT in WD remains highly debated in patients with progressive neurological deterioration and failure to improve with appropriate medical treatment. In case of Wilsonian ALF, early identification is key as mortality is 100% without emergency LT. As many of the copper metabolism parameters are believed to be less reliable in ALF, simple biochemical tests have been proposed for diagnosis of acute WD with good sensitivity and specificity. LT corrects copper metabolism and complications resulting from WD with excellent 1 and 5 year survival. Living related liver transplantation represents an alternative to deceased donor LT with excellent long-term survival, without disease recurrence. Future options may include hepatocyte transplantation and gene therapy. Although both of these have shown promising results in animal models of WD, prospective human studies are much needed to demonstrate their long-term beneficial effects and their potential to replace the need for medical therapy and LT in patients with WD. PMID:22312450

  6. Genetics Home Reference: Mowat-Wilson syndrome

    Science.gov (United States)

    ... expression, and they typically have friendly and happy personalities. Mowat-Wilson syndrome is often associated with an unusually small head ( microcephaly ), structural brain abnormalities, and intellectual disability ranging from moderate to severe. Speech is absent ...

  7. Eigenvalue distributions of Wilson loops

    Energy Technology Data Exchange (ETDEWEB)

    Lohmayer, Robert

    2010-07-01

    In the first part of this thesis, we focus on the distribution of the eigenvalues of the unitary Wilson loop matrix in the two-dimensional case at arbitrary finite N. To characterize the distribution of the eigenvalues, we introduce three density functions (the ''symmetric'', the ''antisymmetric'', and the ''true'' eigenvalue density) which differ at finite N but possess the same infinite-N limit, exhibiting the Durhuus-Olesen phase transition. Using expansions of determinants and inverse determinants in characters of totally symmetric or totally antisymmetric representations of SU(N), the densities at finite N can be expressed in terms of simple sums involving only dimensions and quadratic Casimir invariants of certain irreducible representations of SU(N), allowing for a numerical computation of the densities at arbitrary N to any desired accuracy. We find that the true eigenvalue density, adding N oscillations to the monotonic symmetric density, is in some sense intermediate between the symmetric and the antisymmetric density, which in turn is given by a sum of N delta peaks located at the zeros of the average of the characteristic polynomial. Furthermore, we show that the dependence on N can be made explicit by deriving integral representations for the resolvents associated to the three eigenvalue densities. Using saddle-point approximations, we confirm that all three densities reduce to the Durhuus-Olesen result in the infinite-N limit. In the second part, we study an exponential form of the multiplicative random complex matrix model introduced by Gudowska-Nowak et al. Varying a parameter which can be identified with the area of the Wilson loop in the unitary case, the region of non-vanishing eigenvalue density of the N-dimensional complex product matrix undergoes a topological change at a transition point in the infinite-N limit. We study the transition by a detailed analysis of the average of the

  8. Fifth Lecture

    Science.gov (United States)

    Montessori, Maria

    2013-01-01

    We include the ninth chapter of "Education and Peace" by Maria Montessori (1949) to draw attention to the relationship between peace and sustainability. Nature is an integral part of peace studies. [Reprinted from "Education and Peace," pages 66-70, copyright © 1972 by Montessori-Pierson Publishing Company.

  9. Industry Lecture 2010

    DEFF Research Database (Denmark)

    Kragh, Helge

    2010-01-01

    Sammendrag af "Industry Lecture", Norsk Kjemisk Selskap, Universitetet i Oslo, givet 15/10 2010.......Sammendrag af "Industry Lecture", Norsk Kjemisk Selskap, Universitetet i Oslo, givet 15/10 2010....

  10. The Nambu Jona-Lasinio model with Wilson fermions

    CERN Document Server

    Rantaharju, Jarno

    2017-01-01

    We present a lattice study of a Nambu Jona-Lasinio (NJL) model using Wilson fermions. Four fermion interactions are a natural part of several extensions of the Standard Model, appearing as a low energy description of a more fundamental theory. In models of dynamical electroweak symmetry breaking they are used to endow the Standard Model fermions with masses. In infrared conformal models these interaction, when sufficiently strong, can alter the dynamics of the fixed point, turning the theory into a (near) conformal model with desirable features for model building. As a first step toward the nonperturbative study of these models, we study the phase space of the ungauged NJL model.

  11. The Wilson Governments Policy Towards ELDO

    Science.gov (United States)

    Baker, R.

    This paper discusses the formation and motivation behind the Wilson government's policy towards ELDO. In particular the December 1965 report for the Minister of Aviation, Roy Jenkins, and the assumptions that it makes about the validity of launchers in general and British involvement in ELDO are examined. This examination sustains the argument that the Wilson government wanted to pull out of ELDO from the beginning, and that the only reason that it did not was because of political damage and financial liability. The examination also helps to illustrate why the UK government actively worked towards the demise of ELDO.

  12. Spectrum of the Wilson Dirac operator at finite lattice spacings

    DEFF Research Database (Denmark)

    Akemann, G.; Damgaard, Poul Henrik; Splittorff, Kim

    2011-01-01

    We consider the effect of discretization errors on the microscopic spectrum of the Wilson Dirac operator using both chiral Perturbation Theory and chiral Random Matrix Theory. A graded chiral Lagrangian is used to evaluate the microscopic spectral density of the Hermitian Wilson Dirac operator...... as well as the distribution of the chirality over the real eigenvalues of the Wilson Dirac operator. It is shown that a chiral Random Matrix Theory for the Wilson Dirac operator reproduces the leading zero-momentum terms of Wilson chiral Perturbation Theory. All results are obtained for fixed index...... of the Wilson Dirac operator. The low-energy constants of Wilson chiral Perturbation theory are shown to be constrained by the Hermiticity properties of the Wilson Dirac operator....

  13. Wilson disease : from clinical to molecular

    NARCIS (Netherlands)

    Houwen, Roderick Henk Johan

    1991-01-01

    Wilson disease is an autosomal recessive copper storage disease. It is characterized by an inability of the liver to; excrete copper into bile and to incorporate copper into ceruloplasmin. This results in a gradual accumulation of copper in the liver and subsequently in the brain and other organs,

  14. Kenneth G Wilson (1936–2013)

    Indian Academy of Sciences (India)

    winner of the 1982 Nobel Prize in Physics. The piece brings out the bare facts of Wilson's life in his own words – very few of them, in fact. No one reading it would realize that he was one of the most celebrated among twentieth-century theoretical physicists for changing the perceptions of strongly interacting systems – either ...

  15. Cora Wilson Stewart: Crusader against Illiteracy.

    Science.gov (United States)

    Nelms, Willie

    This book is a biography of Cora Wilson Stewart, a Rowan County, Kentucky, school superintendent who rose to prominence with the establishment of the Moonlight Schools for adults with low literacy levels in 1911. It presents the details of her Kentucky crusade against illiteracy, then examines the personal part of her life as well as her later…

  16. WILSON'S DISEASE (A report of two cases).

    Science.gov (United States)

    Kanitkar, M; JOSHi, S N; Roy, N Dutta

    1994-01-01

    Two cases of Wilson's disease are reported. First case presented with fulminant hepatic failure and had a fatal outcome. The second had an insiduous onset, neurological manifestations, and is progressing satisfactorily on zinc therapy. Problems in diagnosis and treatment are highlighted.

  17. Intrinsic deficiencies of lectures as a teaching method.

    Science.gov (United States)

    Pale, Predrag

    2013-06-01

    Lectures were, still are and seem to remain a dominant form of teaching, despite an increased research and use of other methods of teaching and leverage of technology aimed at improving teaching results and efficiency. Learning, as the result of a lecture, greatly depends on the subject, the competence and abilities of the lecturer as well as on other transient causes. However, lectures also have some intrinsic deficiencies as a teaching method pertinent to their very nature. In order to fully understand the teaching value of lectures and their role and proper use in educational systems, their deficiencies have been studied in a theoretical analysis from the perspective of cognitive learning theories. Fifteen deficiencies have been identified and clustered in three categories based on root causes of deficiencies: synchronicity problems, time constraint and individual student abilities, needs and knowledge. These findings can be used to adjust expected learning outcomes of lectures, to properly (re)design lecture content and process and to design other learning and teaching activities that would compensate and complement lectures. Recommendations are given on replacing and amending lectures with other instructional methods, amending lectures in the course of delivery with additional content and tools and complementing lectures after delivery with content, tools and activities. Suggestions on the use of information technology that could substitute, reduce or eliminate at least some of the deficiencies are made. Lecture captures seem to be valuable supplement for live lectures compensating in all three categories of deficiencies. Suggestions and directions for further research are given.

  18. A history of altruism focusing on Darwin, Allee and E.O. Wilson.

    Science.gov (United States)

    Domondon, Andrew T

    2013-06-01

    The problem of altruism refers to the apparent difficulty in reconciling the existence of altruists, individuals who reduce their own fitness to increase the fitness of others, with natural selection. A historical and philosophical overview of solutions to this apparent contradiction is presented through a close reading of the key texts of Charles Darwin, Warder C. Allee and Edward O. Wilson. Following an analysis of Darwin's explanation for altruism, I examine the ideas of group selection and kin selection advanced by Allee and Wilson, respectively, Attention is also given to the philosophical implications each associated with their respective solutions. Copyright © 2013 Elsevier Ltd. All rights reserved.

  19. William D. Hamilton's Brazilian lectures and his unpublished model regarding Wynne-Edwards's idea of natural selection. With a note on 'pluralism' and different philosophical approaches to evolution.

    Science.gov (United States)

    Coco, Emanuele

    2016-12-01

    In 1975, the English evolutionist William Donald Hamilton (1936-2000) held in Brazil a series of lectures entitled "Population genetics and social behaviour". The unpublished notes of these conferences-written by Hamilton and recently discovered at the British Library-offer an opportunity to reflect on some of the author's ideas about evolution. The year of the conference is particularly significant, as it took place shortly after the applications of the Price equation with which Hamilton was able to build a model that included several levels of selection. In this paper I mainly analyse the inaugural lecture in which Hamilton proposes a simple model to disprove the hypothesis supported by the British zoologist C. Vero Wynne-Edwards (1906-1997) regarding mechanisms to prevent "over-exploitation of the food supply" in "the interests of the survival of the group". The document presented here is of great historical interest. Not only because manuscript offers a model that-since it was intended for teaching purposes-had never before appeared in the published version, but also because of the general index of the lectures that accompanies it. The latter allows us to make some hypothetical considerations on the relationship and differences between kin-selection, group-selection and inclusive fitness that Hamilton wanted to present to the attentive, well-prepared audience of the foreign university that had invited him.

  20. A Geminoid as Lecturer

    DEFF Research Database (Denmark)

    Abildgaard, Julie Rafn; Schärfe, Henrik

    2012-01-01

    In this paper we report our findings from an experiment with the teleoperated android Geminoid-DK. The geminoid took up the role of a university lecturer and delivered a 45 minute lecture in front of 150 freshmen students at Aalborg University. While considering the role of the geminoid in this e......In this paper we report our findings from an experiment with the teleoperated android Geminoid-DK. The geminoid took up the role of a university lecturer and delivered a 45 minute lecture in front of 150 freshmen students at Aalborg University. While considering the role of the geminoid...

  1. Symmetries of Ginsparg-Wilson Chiral Fermions

    OpenAIRE

    Mandula, Jeffrey E.

    2009-01-01

    The group structure of the variant chiral symmetry discovered by Luscher in the Ginsparg-Wilson description of lattice chiral fermions is analyzed. It is shown that the group contains an infinite number of linearly independent symmetry generators, and the Lie algebra is given explicitly. CP is an automorphism of this extended chiral group, and the CP transformation properties of the symmetry generators are found. The group has an infinite-parameter invariant subgroup, and the factor group, wh...

  2. CLASSICS Kenneth G. Wilson – Biographical

    Indian Academy of Sciences (India)

    science from the United States whom we have covered in Resonance came from small town, non-academic backgrounds. Kenneth Wilson is a notable exception. His father ... I went often to M.I.T. to use their com puter and eat lunch with the M.I.T. theory group, led by Francis Low. In 1962 I went to CERN for a calendar year, ...

  3. Wilson lines in the MHV action

    Science.gov (United States)

    Kotko, P.; Stasto, A. M.

    2017-09-01

    The MHV action is the Yang-Mills action quantized on the light-front, where the two explicit physical gluonic degrees of freedom have been canonically transformed to a new set of fields. This transformation leads to the action with vertices being off-shell continuations of the MHV amplitudes. We show that the solution to the field transformation expressing one of the new fields in terms of the Yang-Mills field is a certain type of the Wilson line. More precisely, it is a straight infinite gauge link with a slope extending to the light-cone minus and the transverse direction. One of the consequences of that fact is that certain MHV vertices reduced partially on-shell are gauge invariant — a fact discovered before using conventional light-front perturbation theory. We also analyze the diagrammatic content of the field transformations leading to the MHV action. We found that the diagrams for the solution to the transformation (given by the Wilson line) and its inverse differ only by light-front energy denominators. Further, we investigate the coordinate space version of the inverse solution to the one given by the Wilson line. We find an explicit expression given by a power series in fields. We also give a geometric interpretation to it by means of a specially defined vector field. Finally, we discuss the fact that the Wilson line solution to the transformation is directly related to the all-like helicity gluon wave function, while the inverse functional is a generating functional for solutions of self-dual Yang-Mills equations.

  4. Insights into the management of Wilson's disease.

    Science.gov (United States)

    Kathawala, Mohmadshakil; Hirschfield, Gideon M

    2017-11-01

    Wilson's disease is a rare, inherited autosomal recessive disease of copper metabolism, in which the causative gene, ATP7B, results in absent or reduced function of the ATP7B transporter important for biliary excretion of copper and incorporation of copper into caeruloplasmin. Affected patients accumulate excessive copper within the liver, brain and other tissues. A disease mainly of children, adolescents and young adults; clinical features vary from the asymptomatic state to chronic liver disease, acute liver failure, and neuropsychiatric manifestations. Diagnosis requires a high index of suspicion and is based on a combination of clinical signs, biochemical tests, hepatic copper content assay and mutation analysis of the ATP7B gene; to date, there are more than 500 mutations of ATP7B in patients with Wilson's disease. Early recognition and treatment can result in an excellent prognosis whereas untreated disease is almost always fatal. Drug therapies include chelating agents, such as penicillamine or trientine, and zinc salts. Liver transplantation is curative correcting the underlying pathophysiology and is traditionally indicated in acute liver failure or end-stage liver disease refractory to medical therapy. This review provides an overview of various aspects of Wilson's disease including molecular basis of the disease, clinical features, diagnostic and management strategies with their current limitations.

  5. The Legacy of G. Wilson Knight

    Directory of Open Access Journals (Sweden)

    Raw Laurence

    2017-06-01

    Full Text Available G. Wilson Knight (1897-1985 was one of the most influential Shakespearean critics of the mid-twentieth century. This piece surveys his work from 1930 until the early 1980s. Much affected by the First World War, he developed a style of criticism based on Christian principles of respect for other people and belief in an all-powerful God. Many of his most famous pieces (in THE WHEEL OF FIRE, for instance argue for human insignificance in an indifferent universe. It is up to all of us as individuals to develop methods of coping with this world. Wilson Knight’s ideas gained particular currency during the Second World War, when Britain’s very future seemed at risk due to the threat of Nazi invasion. Although much derided for his use of transcendent language—especially by his contemporary F. R. Leavis—Wilson Knight’s ideas seem to have acquired new significance in a globalized world, where individuals fight to main their identity in a technology-driven environment.

  6. Ted Wilson passes on the torch

    CERN Multimedia

    2003-01-01

    As part of the Laboratory's outreach programme, the CERN Accelerator School (CAS) brings together students and experienced physicists from all over the world with the aim of promoting the understanding of accelerator physics. As head of the School for 11 years, Ted Wilson became a CERN ambassador to the outside community. He retired in March, handing over the reigns of the CAS to Daniel Brandt. Ted Wilson and his assistant, Suzanne von Wartburg, during an EPAC meeting in 1994.The accelerator schools allowed some time for relaxation in the local surrounding for students as well as for the director of CAS.As a boy, Ted Wilson could have embarked on a career in pop music rather than physics, rubbing shoulders at secondary school in Liverpool with two of the future Beatles. But prefering classical music and answering the call of science, he took the more serious of the two paths, studying physics first at Oxford University then at the Rutherford Laboratory. After a year at CERN and four years at the Rutherford La...

  7. Academic Training Lecture - Regular lecture programme

    CERN Multimedia

    PH Department

    2011-01-01

    Wednesday 28, Thursday 29 and Friday 30 September 2011 Supersymmetric Recipes by Prof. Ben Allanech / University of Cambridge, UK  from 11:00 to 12:00 (Europe/Zurich) at CERN ( Main Auditorium, Bldg. 500 ) In these lectures, I shall describe the theory of supersymmetry accessible to people with a knowledge of basic quantum field theory. The lectures will contain recipes of how to calculate which interactions (and which special relations) are in supersymmetry, without providing detailed proofs of where they come from. We shall also cover: motivation for weak-scale supersymmetry and the minimal supersymmetric standard model.

  8. Lectures on combustion theory

    Energy Technology Data Exchange (ETDEWEB)

    Burstein, S.Z.; Lax, P.D.; Sod, G.A. (eds.)

    1978-09-01

    Eleven lectures are presented on mathematical aspects of combustion: fluid dynamics, deflagrations and detonations, chemical kinetics, gas flows, combustion instability, flame spread above solids, spark ignition engines, burning rate of coal particles and hydrocarbon oxidation. Separate abstracts were prepared for three of the lectures. (DLC)

  9. ACADEMIC TRAINING LECTURE

    CERN Multimedia

    Academic Training; Tel 73127

    2001-01-01

    28, 29, 30, 31 May and 1 June REGULAR LECTURE PROGRAMME From 11:00 hrs - Main Auditorium bldg. 500 Quantum computing and Quantum cryptography T. Hey / University of Southampton, GB, and D. Ross / CERN-TH This course will give both an overview and a detailed introduction to quantum computing and quantum cryptography. The first lecture will survey the field, starting from its origins in Feyman's lecture in 1981. The next three lectures will explain in detail the relevance of Bell states and the workings of Grover's Quantum Search and Shor's quantum factorization algorithms. In addition, an explanation of quantum teleportation will be given. The last lecture will survey the recent progress towards realizing working quantum computers and quantum cryptographic systems.

  10. ACADEMIC TRAINING LECTURE

    CERN Document Server

    Academic Training; Tel. 73127

    2001-01-01

    12, 13, 14, 15 & 16 March REGULAR LECTURE PROGRAMME From 11:00 hrs - Main Auditorium bldg. 500 Telecommunication for the future Rob Parker / CERN-IT Few fields have experienced such a high level of technical advance over the last few decades as that of telecommunications. This lecture series will track the evolution of telecommunications systems since their inception, and consider how technology is likely to advance over the next years. A personal view will also be given of the effect of these innovations on our work and leisure activities.The lecture series will be aimed at an audience with no specific technical knowledge of telecommunications.

  11. Wilson's disease--a rare psychiatric presentation.

    Science.gov (United States)

    Aravind, V K; Krishnaram, V D; Neethiarau, V; Srinivasan, K G

    2009-07-01

    The development of extrapyramidal syndrome characterised by rigidity, bradykinesia, dysphagia and dysarthria in a male individual with four distinct episodes of (mania like) behavioural disturbances with fairly good remission in a time frame of five years, in a male individual, was suspected to develop the neurological manifestations of Wilson's disease and was investigated. In the absence of Kayser-Fleischer ring by slit-lamp examination and with normal copper and ceruloplasmin serum levels, the diagnosis was possible because of the positive findings of the magnetic resonance imaging (MRI) studies and increased 24 hours urinary copper levels with the penicillamine challenge test. The findings and its implications are highlighted and discussed.

  12. Feynman Lectures on Computation

    CERN Document Server

    Feynman, Richard Phillips; Allen, Robin W

    1999-01-01

    "When, in 1984-86, Richard P. Feynman gave his famous course on computation at the California Institute of Technology, he asked Tony Hey to adapt his lecture notes into a book. Although led by Feynman,"

  13. Lectures on Dispersion Theory

    Science.gov (United States)

    Salam, A.

    1956-04-01

    Lectures with mathematical analysis are given on Dispersion Theory and Causality and Dispersion Relations for Pion-nucleon Scattering. The appendix includes the S-matrix in terms of Heisenberg Operators. (F. S.)

  14. Symmetries of Ginsparg-Wilson chiral fermions

    Science.gov (United States)

    Mandula, Jeffrey E.

    2009-10-01

    The group structure of the variant chiral symmetry discovered by Lüscher in the Ginsparg-Wilson description of lattice chiral fermions is analyzed. It is shown that the group contains an infinite number of linearly independent symmetry generators, and the Lie algebra is given explicitly. CP is an automorphism of this extended chiral group, and the CP transformation properties of the symmetry generators are found. The group has an infinite-parameter invariant subgroup, and the factor group, whose elements are its cosets, is isomorphic to the continuum chiral symmetry group. Features of the currents associated with these symmetries are discussed, including the fact that some different, noncommuting symmetry generators lead to the same Noether current. These are universal features of lattice chiral fermions based on the Ginsparg-Wilson relation; they occur in the overlap, domain-wall, and perfect-action formulations. In a solvable example, free overlap fermions, these noncanonical elements of lattice chiral symmetry are related to complex energy singularities that violate reflection positivity and impede continuation to Minkowski space.

  15. Hexagon Wilson Loop OPE and Harmonic Polylogarithms

    CERN Document Server

    Papathanasiou, Georgios

    2013-01-01

    A recent, integrability-based conjecture in the framework of the Wilson loop OPE for N=4 SYM theory, predicts the leading OPE contribution for the hexagon MHV remainder function and NMHV ratio function to all loops, in integral form. We prove that these integrals evaluate to a particular basis of harmonic polylogarithms, at any order in the weak coupling expansion. The proof constitutes an algorithm for the direct computation of the integrals, which we employ in order to obtain the full (N)MHV OPE contribution in question up to 6 loops, and certain parts of it up to 12 loops. We attach computer-readable files with our results, as well as an algorithm implementation which may be readily used to generate higher-loop corrections. The feasibility of obtaining the explicit kinematical dependence of the first term in the OPE in principle at arbitrary loop order, offers promise for the suitability of this approach as a non-perturbative description of Wilson loops/scattering amplitudes.

  16. Wilson Prize Lecture: The Novosibirsk Tau/Charm Factory Project: prospect/status

    Science.gov (United States)

    Skrinsky, Alexander

    2002-04-01

    For a long time at the Budker Institute of Nuclear Physics, we develop step-by-step our electron-electron and electron-positron colliders. Now, the VEPP-4M collider (total energy up to 11 GeV), with a special emphasis on Two-Photon hadron physics, is in operation. The new VEPP-2000 collider, as direct extension of our VEPP-2M collider (which finished its very productive life in 2000) to the energy up to 2 GeV total, should start its commissioning phase in 2002. But our main goal in the field (for quite a few years already) is development and construction of Tau/Charm Factory (VEPP-5 collider). There are 3 main modes of operation foreseen: Maximal luminosity - up to 1 \\cdot 10^34 cm-2 sec-1. For reaching of this ambitious goal we intend to use ``round beam'' approach. The approach will be used and studied at VEPP-2000. Longitudinally polarized collisions (proposed and proved theoretically in Novosibirsk still in 1969) with luminosity 1 \\cdot 10^33 cm-2 sec-1. High monochromaticity option (down to few 10 of keV). Now the new injector complex, which would produce intense low emittance bunches of positrons and electrons (for VEPP-5, VEPP-4M and VEPP-2000 efficient operation) is nearing completion. Fraction of the VEPP-5 tunnel is constructed. We hope, when the VEPP-5 collider would become closer to completion, to attract international collaborators to use unique features of our Tau/Charm Factory.

  17. HFE gene mutations and iron metabolism in Wilson's disease.

    Science.gov (United States)

    Erhardt, Andreas; Hoffmann, Arne; Hefter, Harald; Häussinger, Dieter

    2002-12-01

    There is increasing evidence for an interaction between iron and copper metabolism. Iron indices (ferritin, transferrin saturation [TS], serum iron), liver parameters, the prevalence and significance of C282Y and H63D HFE mutations were studied in 40 unrelated, Caucasian patients with Wilson's disease and 295 healthy controls. Due to specific treatment Wilson's disease was well controlled in all but one patient. The allele frequencies for the C282Y (11.3% vs. 6.2%) and the H63D (18.8% vs. 16.4%) mutation did not differ between patients with Wilson's disease and healthy controls. One patient with C282Y homozygous HH and Wilson's disease was identified showing progressive liver disease despite reasonable venesection and copper chelation therapy. No differences in iron indices and liver values were seen between HFE heterozygous and HFE wildtype patients with Wilson's disease. Higher serum ferritin levels were noticed in patients with Wilson's disease compared to healthy controls (149 +/- 26 microg/l vs. 87 +/- 8 microg/l; P Wilson's disease in order to detect iron overload. HFE mutations other than C282Y homozygosity seem to have no impact on iron indices and liver parameters as long as Wilson's disease is controlled.

  18. Fisher, Wall and Wilson on "Punishment": A Critique

    Science.gov (United States)

    Wilson, P. S.

    1973-01-01

    Discussion based on Wilson on the justification of punishment,'' by M. Fisher and G. Wall, Journal of Moral Education, v1 n3; and The justification of punishment,'' by J. Wilson, British Journal of Educational Studies, v19 pt2. (CB)

  19. U(1) Wilson lattice gauge theories in digital quantum simulators

    Science.gov (United States)

    Muschik, Christine; Heyl, Markus; Martinez, Esteban; Monz, Thomas; Schindler, Philipp; Vogell, Berit; Dalmonte, Marcello; Hauke, Philipp; Blatt, Rainer; Zoller, Peter

    2017-10-01

    Lattice gauge theories describe fundamental phenomena in nature, but calculating their real-time dynamics on classical computers is notoriously difficult. In a recent publication (Martinez et al 2016 Nature 534 516), we proposed and experimentally demonstrated a digital quantum simulation of the paradigmatic Schwinger model, a U(1)-Wilson lattice gauge theory describing the interplay between fermionic matter and gauge bosons. Here, we provide a detailed theoretical analysis of the performance and the potential of this protocol. Our strategy is based on analytically integrating out the gauge bosons, which preserves exact gauge invariance but results in complicated long-range interactions between the matter fields. Trapped-ion platforms are naturally suited to implementing these interactions, allowing for an efficient quantum simulation of the model, with a number of gate operations that scales polynomially with system size. Employing numerical simulations, we illustrate that relevant phenomena can be observed in larger experimental systems, using as an example the production of particle–antiparticle pairs after a quantum quench. We investigate theoretically the robustness of the scheme towards generic error sources, and show that near-future experiments can reach regimes where finite-size effects are insignificant. We also discuss the challenges in quantum simulating the continuum limit of the theory. Using our scheme, fundamental phenomena of lattice gauge theories can be probed using a broad set of experimentally accessible observables, including the entanglement entropy and the vacuum persistence amplitude.

  20. Wilson Dslash Kernel From Lattice QCD Optimization

    Energy Technology Data Exchange (ETDEWEB)

    Joo, Balint [Jefferson Lab, Newport News, VA; Smelyanskiy, Mikhail [Parallel Computing Lab, Intel Corporation, California, USA; Kalamkar, Dhiraj D. [Parallel Computing Lab, Intel Corporation, India; Vaidyanathan, Karthikeyan [Parallel Computing Lab, Intel Corporation, India

    2015-07-01

    Lattice Quantum Chromodynamics (LQCD) is a numerical technique used for calculations in Theoretical Nuclear and High Energy Physics. LQCD is traditionally one of the first applications ported to many new high performance computing architectures and indeed LQCD practitioners have been known to design and build custom LQCD computers. Lattice QCD kernels are frequently used as benchmarks (e.g. 168.wupwise in the SPEC suite) and are generally well understood, and as such are ideal to illustrate several optimization techniques. In this chapter we will detail our work in optimizing the Wilson-Dslash kernels for Intel Xeon Phi, however, as we will show the technique gives excellent performance on regular Xeon Architecture as well.

  1. Diagnosis and treatment of Wilson's disease.

    Science.gov (United States)

    Schilsky, Michael L

    2002-02-01

    Wilson's disease (WD) has moved on from being a recognized syndrome that was uniformly fatal to a curative disease for which the genetic basis has been discovered. Most pediatric patients present with hepatic manifestations, but some may have neurologic or psychiatric features. Clinical and biochemical screening, including liver biopsy for hepatic copper analysis, remain the standard for diagnosis, but haplotype analysis for siblings is now available and should be considered for family screening when possible. Lifelong medical therapy remains the mainstay of treatment, but treatment preferences are changing from penicillamine to alternative agents such as trientine and zinc. OLT remains lifesaving for those with fulminant WD and those in whom initial medical therapy fails. The future will probably see the application of rapid and accurate molecular diagnostic testing for this disorder and new therapeutic modalities such as hepatocyte transplantation, gene replacement therapy, and gene modification.

  2. ABJM Wilson loops in arbitrary representations

    Energy Technology Data Exchange (ETDEWEB)

    Hatsuda, Yasuyuki [Deutsches Elektronen-Synchrotron (DESY), Hamburg (Germany). Theory Group; Tokyo Institute of Technology (Japan). Dept. of Physics; Honda, Masazumi [High Energy Accelerator Research Organization (KEK), Tsukuba, Ibaraki (Japan); Moriyama, Sanefumi [Nagoya Univ. (Japan). Kobayashi Maskawa Inst. and Graduate School of Mathematics; Okuyama, Kazumi [Shinshu Univ., Matsumoto, Nagano (Japan). Dept. of Physics

    2013-06-15

    We study vacuum expectation values (VEVs) of circular half BPS Wilson loops in arbitrary representations in ABJM theory. We find that those in hook representations are reduced to elementary integrations thanks to the Fermi gas formalism, which are accessible from the numerical studies similar to the partition function in the previous studies. For non-hook representations, we show that the VEVs in the grand canonical formalism can be exactly expressed as determinants of those in the hook representations. Using these facts, we can study the instanton effects of the VEVs in various representations. Our results are consistent with the worldsheet instanton effects studied from the topological string and a prescription to include the membrane instanton effects by shifting the chemical potential, which has been successful for the partition function.

  3. Nucleon form factors with light Wilson quarks

    CERN Document Server

    Green, Jeremy; Krieg, Stefan; Meinel, Stefan; Negele, John; Pochinsky, Andrew; Syritsyn, Sergey

    2013-01-01

    We present nucleon observables - primarily isovector vector form factors - from calculations using 2+1 flavors of Wilson quarks. One ensemble is used for a dedicated high-precision study of excited-state effects using five source-sink separations between 0.7 and 1.6 fm. We also present results from a larger set of calculations that include an ensemble with pion mass 149 MeV and box size 5.6 fm, which nearly eliminates the uncertainty associated with extrapolation to the physical pion mass. The results show agreement with experiment for the vector form factors, which occurs only when excited-state contributions are reduced. Finally, we show results from a subset of ensembles that have pion mass 254 MeV with varying temporal and spatial box sizes, which we use for a controlled study of finite-volume effects and a test of the "$m_\\pi L=4$" rule of thumb.

  4. Lecture on beam instabilities

    Energy Technology Data Exchange (ETDEWEB)

    Chao, A.

    1999-12-21

    These lectures treat some of the common collective beam instability effects encountered in accelerators. In choosing the material for these lectures, it is attempted to introduce this subject with a more practical approach, instead of a more theoretical approach starting with first principles. After introducing the terminologies, emphasis will be placed on how to apply the lecture material to perform calculations and to make estimates of various instability effects. In the first half of the lectures, after briefly introducing the concepts of impedance and wake field, the authors will discuss a selected list of formulas for the impedances of various accelerator components. Detailed derivations are omitted, allowing time for the students to think through the process of how to apply the knowledge learned. The list of impedances to be covered include: space charge, resistive wall, resonator, wall roughness, and small perturbation on the vacuum chamber wall. Assuming impedances are known, the second half of the lectures addresses the question of how to calculate the power of beam heating, the growth rates, and the thresholds for a list of selected beam instability effects. Again with minimal detailed derivations, the aim is to introduce a collection of formulas, and apply them to linear as well as circular accelerators. The list of beam instability effects to be covered include: loss factor, beam break-up, BNS damping, bunch lengthening, resistive wall instability, head-tail instability, longitudinal head-tail instability, Landau damping, microwave instability, and mode coupling instability.

  5. Obituary: Peter Robert Wilson, 1929-2007

    Science.gov (United States)

    Snodgrass, Herschel B.

    2009-01-01

    It is with great sadness that I report the passing of Peter Robert Wilson, a well-known and well-loved figure in the solar physics community. Peter was on the faculty of the Department of Applied Mathematics at the University of Sydney for 39 years, and Chair of the department for 24 of these years. He was the author or co-author of more than 80 scientific research papers and a book, Solar and Stellar Activity Cycles (1994), published by Cambridge University Press. He died suddenly of a heart attack, at his home in Glebe, Australia, in the early morning of 11 November 2007. Peter was an organizer of, and participant in, many international conferences and workshops. He traveled extensively, holding visiting appointments at the University of Colorado (JILA), at Cambridge University, at the College de France (Paris), and at the California Institute of Technology [CalTech]. Most of his work was in the field of solar physics, but he also did some work on the philosophy of science and on tides. Peter came from a line of mathematicians. His father, Robert Wilson, immigrated to Australia from Glasgow in 1911, and became a mathematics teacher at Scotch College, a private school in Melbourne. There his name was changed to 'Bill' because 'Bob' was already taken." Peter's enjoyment of this story as characteristic of Australian academia (as any fan of Monty Python would understand) is indicative of his infectious sense of humor. In a similar vein, he claimed ancestry traced back to the eighteenth-century Scottish mathematician Alexander Wilson, Professor of Astronomy at the University of Glasgow. That Wilson is famous in the solar physics community for his discovery, known as the "Wilson Effect," of the photospheric depressions associated with sunspots. Peter himself could not resist writing a paper on this subject, and was delighted when the bait was taken by some less-informed colleagues who chided him for "naming an effect after himself." "Bill" Wilson married Naomi

  6. Albert Einstein memorial lectures

    CERN Document Server

    Mechoulam, Raphael; The Israel Academy for Sciences and Humanities

    2012-01-01

    This volume consists of a selection of the Albert Einstein Memorial Lectures presented annually at the Israel Academy of Sciences and Humanities. Delivered by eminent scientists and scholars, including Nobel laureates, they cover a broad spectrum of subjects in physics, chemistry, life science, mathematics, historiography and social issues. This distinguished memorial lecture series was inaugurated by the Israel Academy of Sciences and Humanities following an international symposium held in Jerusalem in March 1979 to commemorate the centenary of Albert Einstein's birth. Considering that Einstein's interests, activities and influence were not restricted to theoretical physics but spanned broad fields affecting society and the welfare of humankind, it was felt that these memorial lectures should be addressed to scientists, scholars and erudite laypersons rather than to physicists alone.

  7. Lectures on Chevalley groups

    CERN Document Server

    Steinberg, Robert

    2016-01-01

    Robert Steinberg's Lectures on Chevalley Groups were delivered and written during the author's sabbatical visit to Yale University in the 1967-1968 academic year. The work presents the status of the theory of Chevalley groups as it was in the mid-1960s. Much of this material was instrumental in many areas of mathematics, in particular in the theory of algebraic groups and in the subsequent classification of finite groups. This posthumous edition incorporates additions and corrections prepared by the author during his retirement, including a new introductory chapter. A bibliography and editorial notes have also been added. This is a great unsurpassed introduction to the subject of Chevalley groups that influenced generations of mathematicians. I would recommend it to anybody whose interests include group theory. -Efim Zelmanov, University of California, San Diego Robert Steinberg's lectures on Chevalley groups were given at Yale University in 1967. The notes for the lectures contain a wonderful exposition of ...

  8. Lectures for CERN pensioners

    CERN Multimedia

    GS Department

    2009-01-01

    The CERN Medical Service and the Pensioners Association are pleased to invite CERN pensioners to a series of lectures given by professors and specialists from the Teaching Hospitals and the Faculty of Medicine of the University of Geneva on the following topic: PROMOTION OF OPTIMUM BRAIN AGEING The lectures will take place in the Main CERN Auditorium (Building 60) from 2.30 p.m. to 4.30 p.m. on the following dates: Thursday 15 January 2009: Diagnosing and treating Alzheimer’s disease Pr Gabriel GOLD Wednesday 25 February 2009: What is the brain reserve? Speaker’s name to be announced at a later date. The lectures will be given in French, with transparencies in English, and will be followed by a wide-ranging debate with the participants. CERN Medical Service - Pensioners Association - CERN-ESO (GAC-EPA)

  9. Lectures on functor homology

    CERN Document Server

    Touzé, Antoine

    2015-01-01

    This book features a series of lectures that explores three different fields in which functor homology (short for homological algebra in functor categories) has recently played a significant role. For each of these applications, the functor viewpoint provides both essential insights and new methods for tackling difficult mathematical problems. In the lectures by Aurélien Djament, polynomial functors appear as coefficients in the homology of infinite families of classical groups, e.g. general linear groups or symplectic groups, and their stabilization. Djament’s theorem states that this stable homology can be computed using only the homology with trivial coefficients and the manageable functor homology. The series includes an intriguing development of Scorichenko’s unpublished results. The lectures by Wilberd van der Kallen lead to the solution of the general cohomological finite generation problem, extending Hilbert’s fourteenth problem and its solution to the context of cohomology. The focus here is o...

  10. Academic Training Lecture - Regular Programme

    CERN Multimedia

    PH Department

    2011-01-01

    Regular Lecture Programme 9 May 2011 ACT Lectures on Detectors - Inner Tracking Detectors by Pippa Wells (CERN) 10 May 2011 ACT Lectures on Detectors - Calorimeters (2/5) by Philippe Bloch (CERN) 11 May 2011 ACT Lectures on Detectors - Muon systems (3/5) by Kerstin Hoepfner (RWTH Aachen) 12 May 2011 ACT Lectures on Detectors - Particle Identification and Forward Detectors by Peter Krizan (University of Ljubljana and J. Stefan Institute, Ljubljana, Slovenia) 13 May 2011 ACT Lectures on Detectors - Trigger and Data Acquisition (5/5) by Dr. Brian Petersen (CERN) from 11:00 to 12:00 at CERN ( Bldg. 222-R-001 - Filtration Plant )

  11. Lectures in general algebra

    CERN Document Server

    Kurosh, A G; Stark, M; Ulam, S

    1965-01-01

    Lectures in General Algebra is a translation from the Russian and is based on lectures on specialized courses in general algebra at Moscow University. The book starts with the basics of algebra. The text briefly describes the theory of sets, binary relations, equivalence relations, partial ordering, minimum condition, and theorems equivalent to the axiom of choice. The text gives the definition of binary algebraic operation and the concepts of groups, groupoids, and semigroups. The book examines the parallelism between the theory of groups and the theory of rings; such examinations show the

  12. Twenty lectures on thermodynamics

    CERN Document Server

    Buchdahl, H A

    2013-01-01

    Twenty Lectures on Thermodynamics is a course of lectures, parts of which the author has given various times over the last few years. The book gives the readers a bird's eye view of phenomenological and statistical thermodynamics. The book covers many areas in thermodynamics such as states and transition; adiabatic isolation; irreversibility; the first, second, third and Zeroth laws of thermodynamics; entropy and entropy law; the idea of the application of thermodynamics; pseudo-states; the quantum-static al canonical and grand canonical ensembles; and semi-classical gaseous systems. The text

  13. ACADEMIC TRAINING LECTURE

    CERN Multimedia

    Academic Training; Tel. 73127

    2001-01-01

    26, 27, 28 February and 1, 2 March REGULAR LECTURE PROGRAMME From 11:00 hrs - Main Auditorium bldg. 500 Recent Results on CP Violation and B Physics P.F. HARRISON / QMW, London, UK With the advent of the asymmetric B factories in Japan and the US, exciting new results on CP Violation and B Physics are starting to be achieved. In these lectures, we review the existing experimental and phenomenological context of these measurements, we compare and contrast the new experimental facilities and discuss the implications of the recent results on our understanding. Finally we summarise the prospects for future developments.

  14. Queering biology, gutting feminism: A review essay of Gut Feminism by Elizabeth A. Wilson (Durham, NC: Duke University Press, 2015).

    Science.gov (United States)

    Rubin, David A

    2017-07-25

    The author reviews Elizabeth A. Wilson's Gut Feminism (2015), arguing that Wilson's book productively challenges some of feminist theory's most entrenched presuppositions: that social, cultural, and discursive frameworks are opposed and superior to biological ones; that biological matter is flat, sovereign, monolithic, and determining; that depression is more a cultural, historical, and psychological phenomenon than a biochemical and pharmaceutical one (and that these nominative distinctions are stable and natural); and finally, that the belly's ruminations (hunger, ingestion, digestion, peristalsis, diarrhea, constipation, and excretion) give no clue as to the complexities of entanglements between gut, psyche, subjectivity, sociality, and hostility.

  15. Summer Student Lecture Programme

    CERN Multimedia

    2004-01-01

    Main Auditorium, bldg. 500 DATE TIME LECTURER TITLE Monday 2 August 09:15 - 10:00 P. Wells (CERN) The Higgs Saga at LEP 10:15 - 11:00 G. Cowan (Univ. of London) Introduction to Statistics (2/3) 11:15 - 12:00 G. Cowan (Univ. of London) Introduction to Statistics (3/3) DATE TIME LECTURER TITLE Tuesday 3 August 09:15 - 10:00 P. Sphicas (CERN) Trigger and Data Acquisition Systems (1/2) 10:15 - 11:00 R. Jacobsen (LBLN) From Raw Data to Physics Results (1/2) 11:15 - 12:00 R. Jacobsen (LBLN) G. Cowan (University of London) Discussion Session DATE TIME LECTURER TITLE Wednesday 4 August 09:15 - 10:00 P. Sphicas (CERN) Trigger and Data Acquisition Systems (2/2) 10:15 - 11:00 R. Jacobsen (LBLN) From Raw Data to Physics Results (2/2) 11:15 - 12:00 N. Palanque-Delabrouille (CEA) Astroparticle Physics (1/3) DATE TIME LECTURER TITLE Thursday 5 August 09:15 - 10:00 N. Palanque-Delabrouille (CEA) Astroparticle Physics (2/3) 10:15 - 11:00 N. Palanque-Delabrouille (CEA) A...

  16. When Lecturing: Teach!

    Science.gov (United States)

    Aiken, Warren R.

    1980-01-01

    Techniques that can be used to make the lecture method of teaching more effective include using pictures or objects to facilitate memory, using guided fantasies to stimulate students' imagination of processes, and the suggestopedia method for memorizing facts, principles, and vocabulary. (MSE)

  17. Organic Lecture Demonstrations.

    Science.gov (United States)

    Silversmith, Ernest F.

    1988-01-01

    Provides a listing of 35 demonstrations designed to generate interest in organic chemistry and help put points across. Topics include opening lecture; molecular structure and properties; halogenation; nucleophilic substitution, alkenes and dienes, stereochemistry, spectroscopy, alcohols and phenols, aldehydes and ketones; carboxylic acids, amines,…

  18. The Harvey lectures, Series 82

    Energy Technology Data Exchange (ETDEWEB)

    Botstein, D.; Cech, T.R.; Hille, B.; Lodish, H.F.; Majerus, P.W.

    1988-01-01

    The Harvey Lecture Series is published annually and provides reviews of research topics in the biomedical sciences. Eight lectures by investigators are included in the volume representing the most recent work in the major laboratories.

  19. Public Lecture: Human Space Exploration

    CERN Multimedia

    CERN. Geneva

    2015-01-01

    Should you wish to attend to this lecture only (and not the full colloquium), please register here: https://indico.cern.ch/event/386996/registration/ Participants to the full colloquium are automatically registered to the public lectures.

  20. Wine: the increasing risk of a highly vulnerable industry globally to natural disasters and climate change (NH Division Outstanding ECS Award Lecture)

    Science.gov (United States)

    Daniell, James E.; Daniell, Trevor M.; Daniell, Katherine A.; Wenzel, Friedemann; Schäfer, Andreas M.; Kunz, Michael; Kunz-Plapp, Tina; Khazai, Bijan; Girard, Trevor; Burford, Robert

    2017-04-01

    Globally, well over 10 trillion in economic losses and over 10 million deaths can be attributed directly to natural disaster events from floods, earthquakes, storms, volcanoes and climatic effects historically (CATDAT - Daniell et al., 2016). When looking at the most vulnerable industries to natural disasters for each dollar invested the wine industry rates very highly, thus showing the risky and vulnerable nature of the wine business. Some effects of climate change will be shifting climates so that new grape growing areas are discovered and some traditional locations will require a change of grape variety to be planted, or will unsatisfactory for quality grape production. As new grape types are developed, some other grape types will become less viable leading to a global shift relative to the current state of the industry. The wine industry has been shown to have major losses via sudden shocks such as earthquakes in Chile (2010), Christchurch (2011) and Napa (2014) and hail through Burgundy (2012-2014). Wineries are often prone to other major disasters such as flood, storms, frost, fire or disease causing structural failure of assets, and significant production losses. Natural and man-made disasters play a key role in wine industry losses, and the variability of seasonal shifts and sudden natural shocks can often play a major role in the lifecycle and indeed the lifetime of wineries. Lessons learnt from winery disasters and climate impacts in Australia, Chile, New Zealand and USA are used as well as a comparison with those in Europe and other vulnerable centralised industries, such as cheese in Italy (2012 earthquake). For various natural disasters the structural engineering issues associated with wineries are examined with respect to infrastructure such as elevated steel tanks, as well as the importance of planning for earthquakes. The potential risk mitigation solutions are often simple to implement and are cost-effective in reducing significantly the risk

  1. [Wilson's disease and its pharmacological treatment].

    Science.gov (United States)

    Hayashi, Hisao; Suzuki, Rie; Wakusawa, Shinya

    2004-11-01

    Wilson's disease is an inherited copper toxicosis caused by defective putative copper transporting ATPase in the liver. Because of impaired biliary secretion, copper remains in the liver, resulting in chronic hepatic lesions including fatty metamorphosis, chronic hepatitis and cirrhosis. In the latter stage, extrapyramidal syndromes may develop with and without symptomatic hepatic lesions. Acute liver damage associated with hemolysis and deep jaundice may be the first manifestation. The majority of patients show hypoceruloplasminemia, which has been used as a screening test for the disease. A large number of mutations in the ATP7B gene have been reported. Thus, genetic diagnosis might be limitedly used to presymptomatic diagnosis of siblings when mutations are identified in an index patient. Introduction of penicillamine caused a revolution in the treatment of patients. Another chelater, trientine, is now available for those intolerant of penicillamine. Tetrathiomolibdate and zinc acetate are additional alternatives currently being tested. Hypoceruloplasminemia and further reduction after chelation therapy may be associated with iron overload. This complication is closely related with impaired transport of ferrous ion due to ferroxidase deficiency. Noncompliance and teratogenicity are other major concerns because any treatment with the agents listed above is a life long regimen. Despite various side effects of penicillamine, its teratogenicity is negligible. These data indicate that penicillamine is the first choice of drug for this disease.

  2. Systems biology approach to Wilson's disease.

    Science.gov (United States)

    Burkhead, Jason L; Gray, Lawrence W; Lutsenko, Svetlana

    2011-06-01

    Wilson's disease (WD) is a severe disorder of copper misbalance, which manifests with a wide spectrum of liver pathology and/or neurologic and psychiatric symptoms. WD is caused by mutations in a gene encoding a copper-transporting ATPase ATP7B and is accompanied by accumulation of copper in tissues, especially in the liver. Copper-chelation therapy is available for treatment of WD symptoms and is often successful, however, significant challenges remain with respect to timely diagnostics and treatment of the disease. The lack of genotype-phenotype correlation remains unexplained, the causes of fulminant liver failure are not known, and the treatment of neurologic symptoms is only partially successful, underscoring the need for better understanding of WD mechanisms and factors that influence disease manifestations. Recent gene and protein profiling studies in animal models of WD began to uncover cellular processes that are primarily affected by copper accumulation in the liver. The results of such studies, summarized in this review, revealed new molecular players and pathways (cell cycle and cholesterol metabolism, mRNA splicing and nuclear receptor signaling) linked to copper misbalance. A systems biology approach promises to generate a comprehensive view of WD onset and progression, thus helping with a more fine-tune treatment and monitoring of the disorder.

  3. Diagnosis of Wilson's disease: a comprehensive review.

    Science.gov (United States)

    Mak, Chloe M; Lam, Ching-Wan

    2008-01-01

    Wilson's disease is an autosomal recessive disorder of copper metabolism. The culprit gene is ATP7B. The worldwide prevalence is about 1 in 30,000, which may vary by population. Higher prevalence rates were reported using more sensitive screening techniques and pilot population screening. Typical presentations include neuropsychiatric and hepatic dysfunction, whereas atypical presentations are protean. Diagnosis relies on a high clinical suspicion, typical neurological symptoms, presence of Kayser-Fleischer rings, and reduced serum ceruloplasmin concentration. The conventional value of gene mutations. Direct molecular diagnosis remains the most decisive tool. Other tests such as non-ceruloplasmin-bound copper are unreliable. Potential pitfalls and limitations of these diagnostic markers are critically reviewed in this paper. The mainstays of therapy are trientine, penicillamine, and/or zinc. Liver transplantation is lifesaving for those with advanced disease. Ceruloplasmin oxidase activity and serum free-copper concentration should be monitored in patients on long-term de-coppering therapy to prevent iatrogenic copper deficiency.

  4. Mowat-Wilson syndrome: A case report

    Directory of Open Access Journals (Sweden)

    Čuturilo Goran

    2009-01-01

    Full Text Available Introduction. Mowat-Wilson syndrome (MWS is characterised by severe mental retardation and multiple congenital anomalies. Key features for diagnosis are specific facial dysmorphism with uplifted ear lobes and Hirschsprung's disease. Ganglionic disorders of the colon, both the number of ganglion cells and the length of the aganglionic segment vary significantly in these patients. The disease is caused by ZFHX1B gene mutation. The management of MWS is symptomatic. Case outline. We report a four-year old boy with mental retardation, specific facial dysmorphy and multiple anomalies. During prenatal follow-up intrauterine growth retardation was revealed. Karyotype was normal. Clinical findings showed that growth and mental retardation, gastrointestinal disturbance and heart defect were predominant. A gastrostoma was inserted. Hypoganglionosis of the colon caused severe obstipation. He had a severe stenosis of the pulmonary artery and was a candidate for cardiac surgery. There were several attempts to establish diagnosis, but so far, without results. Conclusion. Hirschsprung's disease/hypoganglionosis of the colon associated with other congenital anomalies or mental retardation require evaluation for dysmorphic syndromes. One of them is MWS, presented in this report.

  5. Genetic and environmental modifiers of Wilson disease.

    Science.gov (United States)

    Medici, Valentina; Weiss, Karl-Heinz

    2017-01-01

    Wilson disease (WD) is characterized by remarkable variety in its phenotypic presentation. Patients with WD can present with hepatic, neurologic, and psychiatric symptoms combined in different and unpredictable ways. Importantly, no convincing phenotype-genotype correlation has ever been identified, opening the possibility that other genes, aside from ATPase copper-transporting beta (ATP7B), are involved in the pathogenesis of this condition. In addition, modifier genes, or genes that can affect the expression of other genes, may be involved. Clinical and basic science data indicate that environmental and dietary factors can potentially modify gene expression in WD and, consequently, its clinical presentation and course. In particular, previously studied genes include copper metabolism domain-containing 1 (COMMD1), antioxidant 1 copper chaperone (ATOX1), X-linked inhibitor of apoptosis (XIAP), apolipoprotein E (APOE), hemochromatosis (HFE), and 5,10-methylenetetrahydrofolate reductase (MTHFR). Dietary factors include iron and methyl group donors which could affect methionine metabolism and epigenetic mechanisms of gene expression regulation. Most of the work conducted in this field is in its initial stages but it has the potential to change the diagnosis and treatment of WD. © 2017 Elsevier B.V. All rights reserved.

  6. Wilson's disease and other neurological copper disorders.

    Science.gov (United States)

    Bandmann, Oliver; Weiss, Karl Heinz; Kaler, Stephen G.

    2015-01-01

    Summary The classic copper metabolism disorder, Wilson disease (WD), was first defined in 1912. Both early onset presentations in infancy and late onset manifestations in adults > 70 years are now well recognized. Modern biochemical and genetic prevalence studies suggest that WD may be considerably more common than previously appreciated. Early diagnosis of WD is crucial to ensure that patients can be started on adequate treatment but uncertainty remains about the best possible choice of medication. Direct genetic testing for ATP7B mutations is increasingly available to confirm the clinical diagnosis of WD. WD needs to be differentiated from other conditions that present clinically with hepatolenticular degeneration or share biochemical abnormalities with WD, such as reduced serum cerulo plasmin levels. Disordered copper metabolism is also implied in an increasing number of other neurological conditions, including a subtype of axonal neuropathy due to ATP7A mutations, and the common late-onset neurodegenerative disorders Alzheimer’s disease and Parkinson’s disease. PMID:25496901

  7. Copper removal strategies for Wilson's disease crisis in the ICU.

    Science.gov (United States)

    Reynolds, H V; Talekar, C R; Bellapart, J; Leggett, B A; Boots, R J

    2014-03-01

    Wilson's disease is a rare, inherited, autosomal recessive disorder of copper metabolism which leads to an accumulation of copper in body tissues. If a patient develops a Wilson's crisis, mortality can approach 100%. The treatment of such patients is mostly organ support but a possible treatment goal is to try to rapidly remove copper from their system. We performed a literature search on methods for de-coppering strategies for patients in intensive care with known Wilson's disease. We found 11 case reports where therapeutic plasma exchange was used and six case reports where various forms of albumin dialysis were used as techniques for rapidly reducing serum copper levels. To date, the case reports are encouraging that therapeutic plasma exchange and albumin dialysis can either delay or prevent the need for liver transplantation in patients with fulminant hepatic failure due to Wilson's disease. However, these case reports are mainly in the paediatric or young adult population, thus further studies in adults are warranted.

  8. Wilson — Konovalov Disease: Diagnostic Algorithms and Approaches to Treatment

    Directory of Open Access Journals (Sweden)

    S.L. Melanich

    2015-11-01

    Full Text Available Wilson — Konovalov disease is a hereditary disease characterized by progressive accumulation of copper, mainly affecting liver and brain. It is a rare disease and is often diagnosed on later stages, but it is now becoming more common. The article discusses the features of clinical symptoms, diagnostic algorithm for the diagnosis of Wilson — Konovalov disease. The points of treatment, prevention and prognosis are dwelt.

  9. Ladder exponentiation for generic large symmetric representation Wilson loops

    OpenAIRE

    Correa, Diego; Massolo, Fidel(Instituto de Física La Plata, CONICET, Universidad Nacional de La Plata, C.C. 67, La Plata, 1900, Argentina)

    2015-01-01

    A recent proposal was made for a large representation rank limit for which the expectation values of N = 4 $$ \\mathcal{N}=4 $$ super Yang-Mills Wilson loops are given by the exponential of the 1-loop result. We verify the validity of this exponentiation in the strong coupling limit using the holographic D3-brane description for straight Wilson loops following an arbitrary internal space trajectory.

  10. Taking Charge: Walter Sydney Adams and the Mount Wilson Observatory

    Science.gov (United States)

    Brashear, R.

    2004-12-01

    The growing preeminence of American observational astronomy in the first half of the 20th century is a well-known story and much credit is given to George Ellery Hale and his skill as an observatory-building entrepreneur. But a key figure who has yet to be discussed in great detail is Walter Sydney Adams (1876-1956), Hale's Assistant Director at Mount Wilson Observatory. Due to Hale's illnesses, Adams was Acting Director for much of Hale's tenure, and he became the second Director of Mount Wilson from 1923 to 1946. Behind his New England reserve Adams was instrumental in the growth of Mount Wilson and thus American astronomy in general. Adams was hand-picked by Hale to take charge of stellar spectroscopy work at Yerkes and Mount Wilson and the younger astronomer showed tremendous loyalty to Hale and Hale's vision throughout his career. As Adams assumed the leadership role at Mount Wilson he concentrated on making the observatory a place where researchers worked with great freedom but maintain a high level of cooperation. This paper will concentrate on Adams's early years and look at his growing relationship with Hale and how he came to be the central figure in the early history of Mount Wilson as both a solar and stellar observatory. His education, his years at Dartmouth and Yerkes (including his unfortunate encounter with epsilon Leonis), and his formative years on Mount Wilson are all important in learning how he shaped the direction of Mount Wilson and the development of American astronomy in the first half of the 20th century. This latter history cannot be complete until we bring Adams into better focus.

  11. Public Lectures | Events | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Public and special lectures. Academy Public Lectures · Public and special lectures in Mid-Year and Annual Meetings · Platinum Jubilee Lectures. Academy's annual and mid-year meetings include a special lecture by a senior Fellow in the morning of each meeting day and one public lecture by an eminent person, from ...

  12. Cell therapy to remove excess copper in Wilson's disease.

    Science.gov (United States)

    Gupta, Sanjeev

    2014-05-01

    To achieve permanent correction of Wilson's disease by a cell therapy approach, replacement of diseased hepatocytes with healthy hepatocytes is desirable. There is a physiological requirement for hepatic ATP7B-dependent copper (Cu) transport in bile, which is deficient in Wilson's disease, producing progressive Cu accumulation in the liver or brain with organ damage. The ability to repopulate the liver with healthy hepatocytes raises the possibility of cell therapy in Wilson's disease. Therapeutic principles included reconstitution of bile canalicular network as well as proliferation in transplanted hepatocytes, despite toxic amounts of Cu in the liver. Nonetheless, cell therapy studies in animal models elicited major differences in the mechanisms driving liver repopulation with transplanted hepatocytes in Wilson's disease versus nondiseased settings. Recently, noninvasive imaging was developed to demonstrate Cu removal from the liver, including after cell therapy in Wilson's disease. Such developments will help advance cell/gene therapy approaches, particularly by offering roadmaps for clinical trials in people with Wilson's disease. © 2014 New York Academy of Sciences.

  13. Lectures on Quantum Gravity

    CERN Document Server

    Gomberoff, Andres

    2006-01-01

    The 2002 Pan-American Advanced Studies Institute School on Quantum Gravity was held at the Centro de Estudios Cientificos (CECS),Valdivia, Chile, January 4-14, 2002. The school featured lectures by ten speakers, and was attended by nearly 70 students from over 14 countries. A primary goal was to foster interaction and communication between participants from different cultures, both in the layman’s sense of the term and in terms of approaches to quantum gravity. We hope that the links formed by students and the school will persist throughout their professional lives, continuing to promote interaction and the essential exchange of ideas that drives research forward. This volume contains improved and updated versions of the lectures given at the School. It has been prepared both as a reminder for the participants, and so that these pedagogical introductions can be made available to others who were unable to attend. We expect them to serve students of all ages well.

  14. Lecture 2: Software Security

    CERN Multimedia

    CERN. Geneva

    2013-01-01

    Computer security has been an increasing concern for IT professionals for a number of years, yet despite all the efforts, computer systems and networks remain highly vulnerable to attacks of different kinds. Design flaws and security bugs in the underlying software are among the main reasons for this. This lecture addresses the following question: how to create secure software? The lecture starts with a definition of computer security and an explanation of why it is so difficult to achieve. It then introduces the main security principles (like least-privilege, or defense-in-depth) and discusses security in different phases of the software development cycle. The emphasis is put on the implementation part: most common pitfalls and security bugs are listed, followed by advice on best practice for security development, testing and deployment. Sebastian Lopienski is CERN’s deputy Computer Security Officer. He works on security strategy and policies; offers internal consultancy and audit services; develops and ...

  15. Globe: Lecture series

    CERN Multimedia

    2007-01-01

    The LHC: an accelerator of science This series of lectures is all about understanding the scientific and technological challenges of the phenomenal LHC project and assessing its innovations through their everyday applications. Come and take a sneak preview of the LHC! Communicate: the Grid, a computer of global dimensions François Grey, head of communication in CERN’s Information Technology Department How will it be possible for the 15 million billion bytes of data generated by the LHC every year to be handled and stored by a computer that doesn’t have to be the size of a skyscraper? The computer scientists have the answer: the Grid, which will harness the power of tens of thousands of computers all over the world by creating a network of computers and making them operate as one. >>> Lectures are free and require no specialist knowledge. In french. 
 >>> By reservation only: tel. +41 (0)22 767 76 76

  16. ACADEMIC TRAINING LECTURE

    CERN Multimedia

    Françoise Benz

    2002-01-01

    18, 19, 20, 21, 22 November LECTURE FOR POSTGRADUATE STUDENTS From 11:00 hrs - Main Auditorium bldg. 500 Telling the Truth with Statistics R. Barlow / Univ. of Manchester, UK This course of lectures will cover probability, distributions, fitting, errors and confidence levels, for practising High Energy Physicists who need to use Statistical techniques to express their results. Concentrating on these appropriate specialist techniques means that they can be covered in appropriate depth, while assuming only the knowledge and experience of a typical Particle Physicist. The different definitions of probability will be explained, and it will be appear why this basic subject is so controversial; there are several viewpoints and it is important to understand them all, rather than abusing the adherents of different beliefs. Distributions will be covered: the situations they arise in, their useful properties, and the amazing result of the Central Limit Theorem. Fitting a parametrisation to a set of data is one of the m...

  17. Schnabel Engineering Lecture

    OpenAIRE

    Cording, Edward

    2014-01-01

    Schnabel Engineering is pleased to bring you Dr. Edward J. Cording as our eighth lecturer of this series. Dr. Cording is Professor Emeritus of Civil and Environmental Engineering at the University of Illinois at Urbana-Champaign where he has taught and performed research in geotechnical engineering, focusing on rock mechanics, soil-structure interaction, and underground construction. The field has been his laboratory, on engineering projects; beginning in the 1960's with large deep caverns ...

  18. ACADEMIC TRAINING LECTURE

    CERN Multimedia

    Academic Training; Tel. 73127

    2001-01-01

    9, 10 and 11 May REGULAR LECTURE PROGRAMME From 10:00 to 12:00 hrs on 9 and 10 May and on 11 May from 11:00 to 12:00 hrs - Main Auditorium bldg. 500 Cosmology and Particle Physics K. Olive / CERN-TH A general overview of the standard big bang model will be presented with special emphasis on astro-particle physics. Specific topics will include: Inflation, Baryoogenesis, Nucleosynthesis and Dark Matter.

  19. ACADEMIC TRAINING LECTURE

    CERN Multimedia

    Academic Training; Tel. 73127

    2001-01-01

    2, 3, 4, 5 and 6 April REGULAR LECTURE PROGRAMME From 11:00 hrs - Main Auditorium bldg. 500 New Developments in Supersymmetry S. Raby / CERN-TH Introduction to supersymmetric grand unified theories. An introduction to the MSSM and different mechanisms for supersymmetry breaking. Then the details of SU(5) and SO(10) unification, the new gauge sector beyond the standard model, representations of quarks and leptons. Gauge and Yukawa coupling unification and some predictions.

  20. The video lecture

    OpenAIRE

    Crook, Charles; Schofield, Louise

    2017-01-01

    Vocabulary for describing the structures, roles, and relationships characteristic of traditional, or ‘offline’, education has been seamlessly applied to the designs of ‘online’ education. One example is the lecture, delivered as a video recording. The purpose of this research is to consider the concept of ‘lecture’ as realised in both offline and online contexts. We explore how media differences entail different student experiences and how these differences relate to design decisions associat...

  1. Lectures on LHC physics

    CERN Document Server

    Plehn, Tilman

    2012-01-01

    When we try to advance from a solid knowledge of field theory to LHC physics we usually encounter a frustrating problem: in particular Higgs physics and QCD techniques appear as a impenetrable granite block of phenomenological know-how, common lores, and historically grown intuition what works and what does not. I hope this lecture can drill a few holes into the rock and put you into a position to digest advanced writeups as well as some first research papers on the topic.

  2. B.Gregory Lecture

    CERN Multimedia

    Jacob,M

    1987-01-01

    Troisième série de "Gregory lectures" en mémoire de B.Gregory (1919-1977),DG de 1965 à 1970. La première conférence B.Gregory a été donné par le Prof.V.Weisskopf, son prédécesseur. Chris Greeg (?)de Berkley prend aussi la parole

  3. Lectures on Logic and Computation

    DEFF Research Database (Denmark)

    foundational, introductory and advanced courses, as well as workshops, covering a wide variety of topics within the three areas of interest: Language and Computation, Language and Logic, and Logic and Computation. During two weeks, around 50 courses and 10 workshops are offered to the attendants, each of 1.......5 hours per day during a five days week, with up to seven parallel sessions. ESSLLI also includes a student session (papers and posters by students only, 1.5 hour per day during the two weeks) and four evening lectures by senior scientists in the covered areas. The 6 course notes were carefully reviewed...... and selected. The papers are organized in topical sections on computational complexity, multi-agant systems, natural language processing, strategies in games and formal semantics....

  4. Probing Wilson loops in N=4 Chern–Simons-matter theories at weak coupling

    Directory of Open Access Journals (Sweden)

    Luca Griguolo

    2016-02-01

    Full Text Available For three-dimensional N=4 super-Chern–Simons-matter theories associated to necklace quivers U(N0×U(N1×⋯U(N2r−1, we study at quantum level the two kinds of 1/2 BPS Wilson loop operators recently introduced in arXiv:1506.07614. We perform a two-loop evaluation and find the same result for the two kinds of operators, so moving to higher loops a possible quantum uplift of the classical degeneracy. We also compute the 1/4 BPS bosonic Wilson loop and discuss the quantum version of the cohomological equivalence between fermionic and bosonic Wilson loops. We compare the perturbative result with the Matrix Model prediction and find perfect matching, after identification and remotion of a suitable framing factor. Finally, we discuss the potential appearance of three-loop contributions that might break the classical degeneracy and briefly analyze possible implications on the BPS nature of these operators.

  5. Off-shell amplitudes as boundary integrals of analytically continued Wilson line slope

    Energy Technology Data Exchange (ETDEWEB)

    Kotko, P. [Department of Physics, The Pennsylvania State University,University Park, PA 16802 (United States); Serino, M. [The Henryk Niewodniczański Institute of Nuclear Physics, Polish Academy of Sciences,Radzikowskiego 152, 31-342, Kraków (Poland); Staśto, A.M. [Department of Physics, The Pennsylvania State University,University Park, PA 16802 (United States)

    2016-08-03

    One of the methods to calculate tree-level multi-gluon scattering amplitudes is to use the Berends-Giele recursion relation involving off-shell currents or off-shell amplitudes, if working in the light cone gauge. As shown in recent works using the light-front perturbation theory, solutions to these recursions naturally collapse into gauge invariant and gauge-dependent components, at least for some helicity configurations. In this work, we show that such structure is helicity independent and emerges from analytic properties of matrix elements of Wilson line operators, where the slope of the straight gauge path is shifted in a certain complex direction. This is similar to the procedure leading to the Britto-Cachazo-Feng-Witten (BCFW) recursion, however we apply a complex shift to the Wilson line slope instead of the external momenta. While in the original BCFW procedure the boundary integrals over the complex shift vanish for certain deformations, here they are non-zero and are equal to the off-shell amplitudes. The main result can thus be summarized as follows: we derive a decomposition of a helicity-fixed off-shell current into gauge invariant component given by a matrix element of a straight Wilson line plus a reminder given by a sum of products of gauge invariant and gauge dependent quantities. We give several examples realizing this relation, including the five-point next-to-MHV helicity configuration.

  6. Two lectures on technicolor

    Energy Technology Data Exchange (ETDEWEB)

    Lane, K. [Fermi National Accelerator Lab., Batavia, IL (United States)]|[Boston Univ., MA (United States). Dept. of Physics

    2002-07-01

    These two lectures on technicolor and extended technicolor (ETC) were presented at l'Ecole de GIF at LAPP, Annecy-le-Vieux, France, in September 2001. In Lecture I, the motivation and structure of this theory of dynamical breaking of electroweak and flavor symmetries is summarized. The main phenomenological obstacles to this picture flavor-changing neutral currents, precision electroweak measurements, and the large top-quark mass-are reviewed. Then, their proposed resolutions-walking technicolor and top-color-assisted technicolor are discussed. In Lecture II, a scenario for CP violation is presented based on vacuum alignment for technifermions and quarks. It has the novel feature of CP violating phases that are rational multiples of {pi} to better than one part in 10{sup 10} without fine-tuning of parameters. The scheme thereby avoids light axions and a massless up quark. The mix ng of neutral mesons, the mechanism of top-quark mass generation, and the CP-violating parameters {epsilon} and sin(2{beta}) strongly constrain the form of ETC-generated quark mass matrices. (author)

  7. ACADEMIC TRAINING LECTURE

    CERN Multimedia

    Academic Training; Tel. 73127

    2001-01-01

    5, 6, 7, 8 and 9 March REGULAR LECTURE PROGRAMME From 11:00 hrs - Main Auditorium bldg. 500 Tracking at the LHC K. Safarik / CERN-EP The lecture will start with a short history of particle tracking in high-energy physics. Then we will concentrate on tracking in the LHC experiments. We will discuss various tracking devices proposed for these experiments, dividing them into two large groups: solid state detectors and gas detectors. Their characteristics, as well as their behaviour in different external conditions (i.e. magnetic field, radiation) will be compared. Furthermore, we will turn to the question: how to design a tracker using these various technologies, what are the essential parameters to be taken into account and we will apply these considerations to the proposed the LHC detectors. The last part of the lecture will be devoted to tracking software. We will mention simulation and concentrate on track finding and reconstruction, reviewing different algorithms prototyped for the LHC experiments. We will ...

  8. Most recent Web Lectures

    CERN Multimedia

    Steven Goldfarb

    Web Archives of ATLAS Plenary Sessions, Workshops, Meetings, and Tutorials recorded over the past two years are available via the University of Michigan portal here. Most recent additions include the ROOT Workshop held at CERN on March 26-27, the Physics Analysis Tools Workshop held in Bergen, Norway on April 23-27, and the CTEQ Workshop: "Physics at the LHC: Early Challenges" held at Michigan State University on May 14-15. Viewing requires a standard web browser with RealPlayer plug-in (included in most browsers automatically) and works on any major platform. Lectures can be viewed directly over the web or downloaded locally. In addition, you will find access to a variety of general tutorials and events via the portal. Suggestions for events or tutorials to record in 2007, as well as feedback on existing archives is always welcome. Please contact us at wlap@umich.edu. Thank you and enjoy the lectures! The Michigan Web Lecture Team Tushar Bhatnagar, Steven Goldfarb, Jeremy Herr, Mitch McLachlan, Homer A....

  9. Lectures for CERN pensioners

    CERN Multimedia

    SC Unit

    2008-01-01

    The CERN Medical Service and the Pensioners Association are pleased to invite CERN pensioners to a series of lectures given by professors and specialists from the Teaching Hospitals and the Faculty of Medicine of the University of Geneva on the following topic: PROMOTION OF OPTIMUM BRAIN AGEING The lectures will take place in the Main CERN Auditorium (Building 60) from 2.30 p.m. to 4.30 p.m. on the following dates: Wednesday 12 November 2008: Assessing the extent of brain ageing Dr Dina ZEKRY Friday 12 December 2008: Can memory decline be prevented? Pr Jean-Pierre MICHEL Thursday 15 January 2009: Diagnosing and treating Alzheimer’s disease Pr Gabriel GOLD Wednesday 25 February 2009: What is the brain reserve? Speaker’s name to be announced at a later date The lectures will be given in French, with transparencies in English, and will be followed by a wide-ranging debate with the participants. CERN Medical Service - Pensioners Association - CERN-ESO (GAC-EPA)

  10. Summer Student Lecture Programme

    CERN Multimedia

    2004-01-01

    Main Auditorium, bldg. 500 More Information DATE TIME LECTURER TITLE Wednesday 7 July 09:15 - 10:00 L. Fayard, O. Ullaland, D. Heagerty (CERN) Programme Presentation Workshops presentation Information on Computing Rules 10:15 - 11:00 R. Aymar (CERN) Introduction to CERN (1/2) 11:15 - 12:00 J. Engelen (CERN) Introduction to CERN (2/2) 15:00 - 16:30 H. Menzel (CERN) An Introduction to Radiation Protection DATE TIME LECTURER TITLE Thursday 8 july 09:15 - 10:00 L. Di Lella (CERN) Introduction to Particle Physics (1/4) 10:15 - 11:00 L. Di Lella (CERN) Introduction to Particle Physics (2/4) 11:15 - 12:00 P. Chomaz (GANIL / CERN) Fundamental questions in modern nuclear physics: The challenge of exotic nuclei (1/2) DATE TIME LECTURER TITLE Friday 9 July 09:15 - 10:00 L. Di Lella (CERN) Introduction to Particle Physics (3/4) 10:15 - 11:00 P. Chomaz (GANIL / CERN) Fundamental questions in modern nuclear physics: The challenge of exotic nuclei (2/2) 11:15 - 12:00 P....

  11. Emily Wilson, The Death of Socrates

    OpenAIRE

    Orfanos, Charalampos

    2011-01-01

    Dans ce vif essai d’histoire des idées, le lecteur ne trouvera ni bibliographie ni notes ; il devra se contenter d’un bref index général et de quelques recommandations de lecture judicieusement sélectives et savamment commentées (13 p. de « Further Reading » à la fin du volume, divisées par chapitre). Mais il ne sera pas déçu par ce livre curieux, d’une fraîcheur inouïe, d’une drôlerie rarement égalée par un ouvrage savant. Un seul exemple suffira pour en montrer la vivacité de l’écriture. Da...

  12. Pregnancy in Wilson disease - management and outcome.

    Science.gov (United States)

    Pfeiffenberger, Jan; Beinhardt, Sandra; Gotthardt, Daniel N; Haag, Nicola; Freissmuth, Clarissa; Reuner, Ulrike; Gauss, Annika; Stremmel, Wolfgang; Schilsky, Michael L; Ferenci, Peter; Weiss, Karl Heinz

    2017-08-31

    Introduction Wilson disease (WD) is a rare inherited disorder of copper metabolism causing toxic hepatic and neural copper accumulation. Clinical symptoms vary widely, from asymptomatic disease to acute liver failure or chronic liver disease without or with neuropsychiatric symptoms. Continuation of specific medical treatment for WD is recommended during pregnancy, but reports of pregnancy outcomes in WD patients are sparse. Patients and methods In a retrospective, multicenter study, 282 pregnancies in 136 WD patients were reviewed. Age at disease onset, age at conception and WD-specific treatments were recorded. Maternal complications during pregnancy, rate of spontaneous abortions and birth defects were analyzed with respect to medical treatment during pregnancy. Results Worsening of liver function tests was evident during 16/282 (6%) pregnancies and occurred in undiagnosed patients as well as in those under medical treatment. Liver test abnormalities resolved in all cases after delivery. Aggravation of neurological symptoms during pregnancy was rare (1%) but tended to persist after delivery. The overall spontaneous abortion rate in the study cohort was 73/282 (26%). Patients with an established diagnosis of WD receiving medical treatment experienced significantly fewer spontaneous abortions than patients with undiagnosed WD (Odds ratio: 2.853 [95% CI: 1.634-4.982]). Birth defects occurred in 7/209 (3%) live births. Conclusion Pregnancy in WD patients on anti-copper therapy is safe. The spontaneous abortion rate in treated patients was lower than that in therapy-naive patients. Although the teratogenic potential of copper chelators is a concern, the rate of birth defects in our cohort was low. Treatment for WD should be maintained during pregnancy, and patients should be monitored closely for hepatic and neurologic symptoms. This article is protected by copyright. All rights reserved. © 2017 by the American Association for the Study of Liver Diseases.

  13. From rifting to subduction: the role of inheritance in the Wilson Cycle

    Science.gov (United States)

    Beaussier, Stéphane; Gerya, Taras; Burg, Jean-Pierre

    2017-04-01

    The Wilson Cycle entails that oceans close and reopen. This cycle is a fundamental principle in plate tectonics, inferring continuity from divergence to convergence and that continental rifting takes place along former suture zones. This view questions the role of inherited structures at each stage of the Wilson Cycle. Using the 3D thermo-mechanical code, I3ELVIS (Gerya and Yuen 2007) we present a high-resolution continuous model of the Wilson cycle from continental rifting, breakup and oceanic spreading to convergence and spontaneous subduction initiation. Therefore, all lateral and longitudinal structures of the lithospheres are generated self-consistently and are consequences of the initial continental structure, tectono-magmatic inheritance and material rheology. In the models, subduction systematically initiates off-ridge and is controlled by the convergence-induced swelling of the ridge. Geometry and dynamics of the developing off-ridge subduction is controlled by four main factors: (1) the obliquity of the ridge with respect to the convergence direction; (2) fluid-induced weakening of the oceanic crust; (3) irregularity of ridge and margins inherited from rifting and spreading; (4) strain localization at transform faults formed during ocean floor spreading. Further convergence can lead to obduction of the oceanic crust and segments of ridge after the oceanic lithosphere is entrained into subduction. We show that the main parameters controlling the occurrence and geometry of obducted ophiolite are the convergence rate and the inherited structure of the passive margins and ridge. Our numerical experiments results show the essential role played by inheritance during the Wilson Cycle and are consistent with nature observations such as the tectonic history of the Oman subduction-obduction system. REFERENCES Gerya, T. V., and D. A. Yuen. 2007: "Robust Characteristics Method for Modelling Multiphase Visco-Elasto-Plastic Thermo-Mechanical Problems, Physics of the

  14. Lectures in Micro Meteorology

    DEFF Research Database (Denmark)

    Larsen, Søren Ejling

    This report contains the notes from my lectures on Micro scale meteorology at the Geophysics Department of the Niels Bohr Institute of Copenhagen University. In the period 1993-2012, I was responsible for this course at the University. At the start of the course, I decided that the text books...... available in meteorology at that time did not include enough of the special flavor of micro meteorology that characterized the work of the meteorology group at Risø (presently of the Institute of wind energy of the Danish Technical University). This work was focused on Boundary layer flows and turbulence...

  15. Joseph Mountin Lecture

    Centers for Disease Control (CDC) Podcasts

    2009-10-26

    In this podcast, William H. Foege, MD, MPH delivers the 29th Annual Joseph W. Mountin Lecture. Dr. Foege was a key leader in the smallpox effort and worked as an epidemiologist in the successful eradication campaign in the 1970s. Dr. Foege became chief of the Smallpox Eradication Program at CDC, and was appointed director of CDC in 1977.  Created: 10/26/2009 by Centers for Disease Control and Prevention (CDC).   Date Released: 10/29/2009.

  16. Lectures on electromagnetism

    CERN Document Server

    Das, Ashok

    2013-01-01

    These lecture notes on electromagnetism have evolved from graduate and undergraduate EM theory courses given by the author at the University of Rochester, with the basics presented with clarity and his characteristic attention to detail. The thirteen chapters cover, in logical sequence, topics ranging from electrostatics, magnetostatics and Maxwell's equations to plasmas and radiation. Boundary value problems are treated extensively, as are wave guides, electromagnetic interactions and fields. This second edition comprises many of the topics expanded with more details on the derivation of vari

  17. Lectures in particle physics

    CERN Document Server

    Green, Dan

    1994-01-01

    The aim of this book on particle physics is to present the theory in a simple way. The style and organization of the material is unique in that intuition is employed, not formal theory or the Monte Carlo method. This volume attempts to be more physical and less abstract than other texts without degenerating into a presentation of data without interpretation.This book is based on four courses of lectures conducted at Fermilab. It should prove very useful to advanced undergraduates and graduate students.

  18. ACADEMIC TRAINING LECTURE

    CERN Multimedia

    Academic Training; Tel. 73127

    2001-01-01

    26, 27, 28, 29 and 30 March REGULAR LECTURE PROGRAMME From 11:00 hrs - Main Auditorium bldg. 500 Introduction to General Relativity and Black Holes T. Damour / IHES, Bures-sur-Yvette, F. Conceptual foundations of General Relativity (GR). Uniqueness of GR. Mathematical framework: tensor calculus, Riemannian geometry, connection, 'spin' connection, curvature, Cartan's form calculus. Hilbert-Einstein action, Einstein equations. Weak gravitational fields. Post Newtonian Approximation. Gravitanional Waves. Exact solutions. Killing vectors. Experimental tests. Black Holes: extensions of the Schwarzschild solution; Kerr-Newman holes; no-hair theorems; energtics of black holes; the membrane approach; quantum mechanics of black holes; Bekenstein entropy; Hawking temperature; black holes and string theory.

  19. Lectures in scattering theory

    CERN Document Server

    Sitenko, A G

    1971-01-01

    Lectures in Scattering Theory discusses problems in quantum mechanics and the principles of the non-relativistic theory of potential scattering. This book describes in detail the properties of the scattering matrix and its connection with physically observable quantities. This text presents a stationary formulation of the scattering problem and the wave functions of a particle found in an external field. This book also examines the analytic properties of the scattering matrix, dispersion relations, complex angular moments, as well as the separable representation of the scattering amplitude. Th

  20. The Oskar Klein memorial lectures

    CERN Document Server

    1994-01-01

    The series of Oskar Klein Memorial Lectures is a must-read for those keenly involved or simply interested in exploring the many fascinating aspects of Physics. This volume presents two landmark lectures given by Hans Bethe in October 1990 and Alan H. Guth in June 1991 under the series of Oskar Klein Memorial Lectures. Hans Bethe's lectures dealt with two themes: the astrophysical importance of neutrinos in supernova outbursts and a theoretical account of neutrinos through observations of the neutrino flux from the centre of the sun. Anyone interested in understanding the processes involved in

  1. Lectures on Lie groups

    CERN Document Server

    Hsiang, Wu-Yi

    2017-01-01

    This volume consists of nine lectures on selected topics of Lie group theory. We provide the readers a concise introduction as well as a comprehensive 'tour of revisiting' the remarkable achievements of S Lie, W Killing, É Cartan and H Weyl on structural and classification theory of semi-simple Lie groups, Lie algebras and their representations; and also the wonderful duet of Cartans' theory on Lie groups and symmetric spaces.With the benefit of retrospective hindsight, mainly inspired by the outstanding contribution of H Weyl in the special case of compact connected Lie groups, we develop the above theory via a route quite different from the original methods engaged by most other books.We begin our revisiting with the compact theory which is much simpler than that of the general semi-simple Lie theory; mainly due to the well fittings between the Frobenius-Schur character theory and the maximal tori theorem of É Cartan together with Weyl's reduction (cf. Lectures 1-4). It is a wonderful reality of the Lie t...

  2. ACADEMIC TRAINING LECTURE

    CERN Multimedia

    Academic Training; Tel. 73127

    2001-01-01

    14, 15 and 16 May REGULAR LECTURE PROGRAMME 14, 15 May from 10:00 to 12:00 hrs - Main Auditorium bldg. 500 16 May from 11:00 to 12:00 hrs - Council Chamber, bldg 503 Modern Signal Processing: Wavelets vs. Fourier M. Vetterli / EPFL, Lausanne, CH and UC Berkeley Wavelets have established themselves as an important tool in modern signal processing as well as in applied mathematics. This is linked to several facts, among others: New theoretical advances have been achieved, like new forms of 4 time-frequency bases for signal analysis. Efficient computational algorithms are available. Many applications either used similar ideas, like for example the concept of multiresolution, or took advantage of the unified framework provided by wavelets. This combination of elegant theory, efficient algorithms, and successful applications makes the field of wavelets and signal processing quite exciting. It is the purpose of these lectures to establish the theory necessary to understand wavelets and related constructions. A...

  3. ACADEMIC TRAINING LECTURE

    CERN Multimedia

    Academic Training; Tel. 73127

    2001-01-01

    14, 15 and 16 May REGULAR LECTURE PROGRAMME 14, 15 May from 10:00 to 12:00 hrs - Main Auditorium bldg. 500 16 May from 11:00 to 12:00 hrs - Council Chamber, bldg 503 Modern Signal Processing: Wavelets vs. Fourier M. Vetterli / EPFL, Lausanne, CH and UC Berkeley Wavelets have established themselves as an important tool in modern signal processing as well as in applied mathematics. This is linked to several facts, among others: i. New theoretical advances have been achieved, like new forms of 4 time-frequency bases for signal analysis. ii. Efficient computational algorithms are available. iii. Many applications either used similar ideas, like for example the concept of multiresolution, or took advantage of the unified framework provided by wavelets. This combination of elegant theory, efficient algorithms, and successful applications makes the field of wavelets and signal processing quite exciting. It is the purpose of these lectures to establish the theory necessary to understand wavelets and related construct...

  4. SUMMER STUDENT LECTURE PROGRAMME

    CERN Multimedia

    Françoise Benz

    2002-01-01

    SUMMER STUDENT LECTURE PROGRAMME Main Auditorium, bldg. 500   DATE TIME LECTURER TITLE Monday 29 July 09:15 - 10:00 R. RATTAZZI Beyond the Standard Model (3/3) 10:15 - 11:00 P. WELLS Experimental test of the SM - LEP (3/3) 11:15 - 12:00 P. WELLS Discussion Session 14:00 - 16:00 R. ASSMANN The CLIC Concept for a Future Particle Collider at the Energy Frontier Tuesday 30 July 09:15 - 10:00 F. ANTINORI Heavy Ions (1/2) 10:15 - 12:00 F. DYDAK Neutrino Physics (1&2/4) Wednesday 31 July  09:15 - 10:00 F. ANTINORI Heavy Ions (2/2) 10:15 - 11:00 F. DYDAK Neutrino Physics (3/4) 11:15 - 12:00 F. DYDAK / F. ANTINORI Discussion Session Thursday 1 August 09:15 - 10:00 T. NAKADA CP Violation (1/4) 10:15 - 11:00 F. DYDAK Neutrino Physics (4/4) 11:15 - 12:00 F. BEDESCHI Experimental test of the SM Tevatron (1/2) Friday 2 August 09:15 - 10:00 T. NAKADA CP Violation (2/4) 10:15 ? 11:00 F. BEDESCHI Experimental test of the SM Tevatron (2/2) 11:15 ? 12:00 F. BEDESCHI / T. NAKADA Di...

  5. SUMMER STUDENT LECTURE PROGRAMME

    CERN Multimedia

    Françoise Benz

    2002-01-01

    Main Auditorium, bldg. 500   DATE TIME LECTURER TITLE Monday 5 August 09:15-10:00 F. GIANOTTI LHC Physics (1/3) 10:15-12:00 T. NAKADA CP Violation (3&4/4) Tuesday 6 August 09:15-10:00 F. GIANOTTI LHC Physics (2/3) 10:15-11:00 R. JACOBSEN From Raw Data to Physics Results (1/3) 11:15-12:00 R. JACOBSEN / T. NAKADA Discussion Session Wednesday 7 August 09:15-10:00 F. GIANOTTI LHC Physics (3/3) 10:15-11:00 R. JACOBSEN From Raw Data to Physics Results (2/3) 11:15-12:00 J. LESGOURDES Cosmology (1/4) 14:00-16:00 C. BENVENUTI Basic Science, Society, and Technological Innovation (Council Chamber, bldg. 503) Thursday 8 August 09:15-10:00 J. LESGOURDES Cosmology (2/4) 10:15-11:00 R. JACOBSEN From Raw Data to Physics Results (3/3) 11:15-12:00 J. CARR / J. LESGOURDES Discussion Session Friday 9 August 09:15-11:00 J. LESGOURDES Cosmology (3&4/4) 11:15-12:00 C. JARLSKOG Historic Lecture 14:00-16:00 Course Review Monday 12 August 09:15-12:00 Students Sessi...

  6. Lectures on Quantum Mechanics

    CERN Document Server

    Basdevant, Jean-Louis

    2007-01-01

    Beautifully illustrated and engagingly written, Lectures on Quantum Mechanics presents theoretical physics with a breathtaking array of examples and anecdotes. Basdevant's style is clear and stimulating, in the manner of a brisk classroom lecture that students can follow with ease and enjoyment. Here is a sample of the book's style, from the opening of Chapter 1: "If one were to ask a passer-by to quote a great formula of physics, chances are that the answer would be 'E = mc2'. Nevertheless, the formula 'E=hV' which was written in the same year 1905 by the same Albert Einstein, and which started quantum theory, concerns their daily life considerably more. In fact, of the three watershed years for physics toward the beginning of the 20th century - 1905: the Special Relativity of Einstein, Lorentz and Poincaré; 1915: the General Relativity of Einstein, with its extraordinary reflections on gravitation, space and time; and 1925: the full development of Quantum Mechanics - it is surely the last which has the mos...

  7. Strings in bubbling geometries and dual Wilson loop correlators

    Science.gov (United States)

    Aguilera-Damia, Jeremías; Correa, Diego H.; Fucito, Francesco; Giraldo-Rivera, Victor I.; Morales, Jose F.; Pando Zayas, Leopoldo A.

    2017-12-01

    We consider a fundamental string in a bubbling geometry of arbitrary genus dual to a half-supersymmetric Wilson loop in a general large representation R of the SU( N) gauge group in N=4 Supersymmetric Yang-Mills. We demonstrate, under some mild conditions, that the minimum value of the string classical action for a bubbling geometry of arbitrary genus precisely matches the correlator of a Wilson loop in the fundamental representation and one in a general large representation. We work out the case in which the large representation is given by a rectangular Young tableau, corresponding to a genus one bubbling geometry, explicitly. We also present explicit results in the field theory for a correlator of two Wilson loops: a large one in an arbitrary representation and a "small" one in the fundamental, totally symmetric or totally antisymmetric representation.

  8. Hallazgo del Falarópodo de Wilson (Steganopus Tricolor en Colombia

    Directory of Open Access Journals (Sweden)

    Dugand Armando

    1947-06-01

    Full Text Available La familia de las Falaropódidas (Charadriiformes.-Sub-Orden Charadrii no ha sido señalada todavía en Colombia. Por lo tanto es interesante registrar aquí por primera vez su presencia ocasional en este país con un ejemplar del Falarópodo de Wilson coleccionado cerca de Popayán, que ha llegado a nuestro Instituto como parte de un canje de pieles con el Museo de Historia Natural de la Universidad del Cauca.

  9. BPS Wilson loops in Minkowski spacetime and Euclidean space

    OpenAIRE

    Ouyang, Hao; Wu, Jun-Bao; Zhang, Jia-ju

    2015-01-01

    We give evidence that spacelike BPS Wilson loops do not exist in Minkowski spacetime. We show that spacelike Wilson loops in Minkowski spacetime cannot preserve any supersymmetries, in $d = 4$ $\\mathcal N = 4$ super Yang-Mills theory, $d = 3$ $\\mathcal N = 2$ super Chern-Simons-matter theory, and $d = 3$ $\\mathcal N = 6$ Aharony-Bergman-Jafferis-Maldacena theory. We not only show this using infinite straight lines and circles as examples, but also we give proofs for general curves. We attribu...

  10. ESP Methodology for Science Lecturers.

    Science.gov (United States)

    Rogers, Angela; Mulyana, Cukup

    A program designed to teach university science lecturers in Indonesia how to design and teach one-semester courses in English for special purposes (ESP) is described. The program provided lecturers with training in language teaching methodology and course design. The piloting of the teacher training course, focusing on physics instruction, is…

  11. ACADEMIC TRAINING LECTURE

    CERN Multimedia

    Academic Training; Tel. 73127

    2001-01-01

    8, 9, 10, 11 and 12 October LECTURES FOR POSTGRADUATE STUDENTS From 10:00 hrs - Main Auditorium bldg. 500 Introduction to Field Theory R. Kleiss / University of Nijmegen, NL Starting from the notion of path integrals as developed by Feynman, we discuss field theory in zero spacetime dimensions. The concepts of perturbation expansions, connected amplitudes, Feynman diagrams, classical solutions, renormalization and the effective action are developed. The model is extended to four spacetime dimensions, and the full Feynman rules for relativisitc scalar theory derived. The S matrix and the concept of unitarity are discussed, leading to the amputation rules for S matrix elements from considerations of unitarity. The rules are extended to include particles with spin-1/2 and spin-1. The high-energy behaviour of the theory is discussed as a method to derive the gauge symmetry of the various models.

  12. ACADEMIC TRAINING LECTURE

    CERN Multimedia

    Academic Training; Tel. 73127

    2001-01-01

    11, 12, 13, 14 and 15 June REGULAR LECTURE PROGRAMME From 11:00 hrs - Main Auditorium bldg. 500 What have we learned from LEP J. Ellis / CERN-TH The basic formalism of the Standard Model will be reviewed, and the limited state of our knowledge before the start-up of LEP will be recalled. Neutrino counting at LEP will be compared with astrophysical and cosmological constraints. The interpretation of precision electroweak data will be discussed, including their predictions for the top quark and the Higgs boson, and the hints they offer for the future direction beyond the Standard Model: probably a weakly-interacting theory that may be extrapolated up to a grand unification scale. Topics in QCD and heavy-flavour physics will be discussed briefly, and topics in W physics at greater length. Direct LEP searches for the Higgs boson and supersymmetric particles will be discussed, and the prospects for their discoveries at future accelerators will be previewed.

  13. ACADEMIC TRAINING LECTURE

    CERN Multimedia

    Academic Training; Tel. 73127

    2001-01-01

    19, 20, 21, 22 and 23 February REGULAR LECTURE PROGRAMME From 11:00 hrs - 19, 20 and 21 February Main Auditorium bldg. 500, 22 and 23 February Council Chamber, bldg 503 Introduction to Cryogenic Engineering J.G. Weisend / SLAC, Stanford, USA Cryogenic engineering is an important speciality at CERN. With the construction of LHC, this technology will have an even greater impact on machine operations. The goal of the course is to give people not working in cryogenics an appreciation of the basic principals and problems associated with the field. The course will also provide a foundation for future learning in cryogenics. Topics to be covered will include: properties of cryogenic fluids and materials, refrigeration, cryostat design, instrumentation, safety and propertiesof He II. Examples of working cryogenic systems, many of them from high energy physics, will be presented.

  14. Lectures on LHC physics

    CERN Document Server

    Plehn, Tilman

    2015-01-01

    With the discovery of the Higgs boson, the LHC experiments have closed the most important gap in our understanding of fundamental interactions, confirming that such interactions between elementary particles can be described by quantum field theory, more specifically by a renormalizable gauge theory. This theory is a priori valid for arbitrarily high energy scales and does not require an ultraviolet completion. Yet, when trying to apply the concrete knowledge of quantum field theory to actual LHC physics - in particular to the Higgs sector and certain regimes of QCD - one inevitably encounters an intricate maze of phenomenological know-how, common lore and other, often historically developed intuitions about what works and what doesn’t. These lectures cover three aspects to help understand LHC results in the Higgs sector and in searches for physics beyond the Standard Model: they discuss the many facets of Higgs physics, which is at the core of this significantly expanded second edition; then QCD, to the deg...

  15. Lectures on algebraic statistics

    CERN Document Server

    Drton, Mathias; Sullivant, Seth

    2009-01-01

    How does an algebraic geometer studying secant varieties further the understanding of hypothesis tests in statistics? Why would a statistician working on factor analysis raise open problems about determinantal varieties? Connections of this type are at the heart of the new field of "algebraic statistics". In this field, mathematicians and statisticians come together to solve statistical inference problems using concepts from algebraic geometry as well as related computational and combinatorial techniques. The goal of these lectures is to introduce newcomers from the different camps to algebraic statistics. The introduction will be centered around the following three observations: many important statistical models correspond to algebraic or semi-algebraic sets of parameters; the geometry of these parameter spaces determines the behaviour of widely used statistical inference procedures; computational algebraic geometry can be used to study parameter spaces and other features of statistical models.

  16. ACADEMIC TRAINING LECTURE

    CERN Multimedia

    Academic Training; Tel. 73127

    2001-01-01

    21, 22, 23 November LECTURES FOR POSTGRADUATE STUDENTS From 11:00 hrs - Council Chamber bldg. 503 on 21 November Auditorium, bldg 500 on 22, 23 November Introduction to symmetry breaking phenomena in physics E. Brezin / ENS, Paris, F. The notion of broken symmetries started slowly to emerge in the 19th century. The early studies of Pasteur on the parity asymmetry of life, the studies of Curie on piezoelectricity and on the symmetries of effects versus the symmetry of causes (which clearly excluded spontaneous symmetry breaking), are important historical landmarks. However the possibility of spontaneous symmetry breaking within the usual principles of statistical mechanics, waited for the work of Peierls and Onsager. The whole theory of phase transitions and critical phenomena, as well as the construction of field theoretic models as long distance limit of yet unknown physics, relies nowadays on the concept of criticality associated to spontaneous symmetry breaking. The phenomena of Goldstone bosons, of Meissn...

  17. Göttingen Lectures

    CERN Document Server

    Woyczyński, Wojbor A

    1998-01-01

    These lecture notes are woven around the subject of Burgers' turbulence/KPZ model of interface growth, a study of the nonlinear parabolic equation with random initial data. The analysis is conducted mostly in the space-time domain, with less attention paid to the frequency-domain picture. However, the bibliography contains a more complete information about other directions in the field which over the last decade enjoyed a vigorous expansion. The notes are addressed to a diverse audience, including mathematicians, statisticians, physicists, fluid dynamicists and engineers, and contain both rigorous and heuristic arguments. Because of the multidisciplinary audience, the notes also include a concise exposition of some classical topics in probability theory, such as Brownian motion, Wiener polynomial chaos, etc.

  18. Nanoscopy with Focused Light (Nobel Lecture).

    Science.gov (United States)

    Hell, Stefan W

    2015-07-06

    A picture is worth a thousand words-This doesn't only apply to everyday life but also to the natural sciences. It is, therefore, probably not by chance that the historical beginning of modern natural sciences very much coincides with the invention of light microscopy. S. W. Hell shows in his Nobel Lecture that the diffraction resolution barrier has been overcome by using molecular state transitions (e.g. on/off) to make nearby molecules transiently discernible. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  19. On the chirally rotated Schroedinger functional with Wilson fermions

    Energy Technology Data Exchange (ETDEWEB)

    Gonzalez Lopez, Jenifer

    2011-05-25

    There are many phenomena in nature, which are closely linked to the low energy regime of QCD. From a theoretical point of view, these low energy phenomena can be dealt with only by means of non-perturbative methods. It is the central goal of this thesis to provide a framework for such a nonperturbative renormalization. For that purpose, we employ a 4-dimensional lattice as a regulator of QCD. As a renormalization scheme, we propose a finite volume Schroedinger functional scheme and here in particular, the chirally rotated Schroedinger functional ({chi}SF). We first perform analytical studies of the {chi}SF at tree-level of perturbation theory, in the continuum and on the lattice. We study the eigenvalue spectrum of the continuum Dirac operator, equipped with chirally rotated SF boundary conditions, and derive the corresponding quark propagator. We then determine the tree-level quark propagator on the lattice, employing massless Wilson fermions as a regulator of the theory. Beyond tree-level, all studies are performed in the quenched approximation of QCD, as a first, computationally much simpler step to understand the properties of the newly proposed {chi}SF scheme. One of the main targets of the present work, has been to perform the non-perturbative tuning of the two required coefficients of the {chi}SF scheme, such that a well defined continuum limit can be reached. We demonstrate, as the first main result of this thesis, that the tuning is feasible and that, moreover, physical quantities are insensitive to the particular tuning condition. As in any lattice regularization with SF-like boundary conditions, there are also in the {chi}SF a couple of counterterms at the boundaries, whose coefficients need to be tuned in order to remove the O(a) discretization effects originated at the boundaries. However, besides these boundary O(a) effects, the {chi}SF is expected to be compatible with bulk automatic O(a)-improvement. We show here that, indeed, the scaling behavior

  20. The Challenges of Listening to Academic Lectures for EAP Learners and the Impact of Metacognition on Academic Lecture Listening Comprehension

    Directory of Open Access Journals (Sweden)

    Maryam Rahimirad

    2015-06-01

    Full Text Available Academic listening skill is an indispensable necessity for English for academic purposes (EAP students in English-medium universities and also critical for their future success in comprehending conference lectures. But due to the specific nature of such academic lectures, nonnative students all too often face challenges in getting a full command of this task. This study investigates the challenges of listening to academic lectures and the impact of related metacognitive strategies on academic lecture listening comprehension on a group of Iranian learners in an EAP workshop. Fifteen academic staff who took part in two intact classes at the University of Qom, Iran, were randomly assigned to treatment (N = 8 and control (N = 7 groups. The treatment group received 16 hr of metacognitive strategy instruction based on the models proposed by Vandergrift during academic listening instruction, while the control group was just exposed to academic lectures with no explicit strategy instruction. The academic listening sections of the British International English Language Testing System (IELTS were utilized to measure the listening comprehension of both groups before and after the treatment. The results of the data analysis determined that the experimental group significantly outperformed the control group in the listening posttest. The interviews before and after the treatment revealed details of challenges in academic lecture comprehension and also shed light on the perception of the learners regarding metacognitive strategy instruction and the frequency of main metacognitive strategies used in comprehending academic lectures.

  1. Obituary: Andrew Stephen Wilson, 1947-2008

    Science.gov (United States)

    Veilleux, Sylvain

    2009-01-01

    On 24 May 2008, Andrew Stephen Wilson passed away at the age of 61, in his home in Silver Spring, Maryland, from complications resulting from a painful spinal illness. Andrew was arguably one of the first truly multi-wavelength astronomers of his generation. His scientific work on active galactic nuclei [AGN] spanned the entire electromagnetic spectrum from the radio to the X-rays. Andrew was born in Doncaster, Yorkshire, England, on 26 March 1947. He was the younger of two brothers whose births were separated by the Second World War. His father, Norman, came from a relatively affluent family who were coal merchants. His mother, Mary, came from a less comfortable background, one of seven children, daughter of a skilled cabinet maker/French polisher, who went through a very hard time during the depression. As a teacher, she placed enormous value on hard work and education as a way of gaining advancement in life. When Andrew was four, the family moved to Skipton, a nice market town in the Yorkshire dales. Andrew went to a small village school until age eleven when he entered Ermysted's Grammar School. He was an enthusiastic soccer and cricket player. He never lost his enthusiasm for soccer and supported the local soccer team, Leeds United, for all his life. Andrew also followed the Yorkshire county cricket team. Andrew's interest in astronomy stemmed from the fact that at Ermysted's Grammar School someone donated a four-inch refracting telescope, so he and his friends used to go back in the evenings to investigate the rings of Saturn, the moons of Jupiter, and various nebulae. While an undergraduate at Cambridge, Andrew joined the astronomy club and ground an 8-inch mirror by hand as a part of a telescope that he set up in the backyard of his parents' house. Andrew spent hours observing with this telescope, and it was the wonder of the family. At Cambridge, Andrew obtained his bachelor's degree with first-class honors in 1969. During a short visit in London with his

  2. Alagille Syndrome and Wilson Disease in Siblings: A Diagnostic Conundrum

    Directory of Open Access Journals (Sweden)

    Meghan Amson

    2012-01-01

    Full Text Available The authors describe two siblings, each with a different, rare genetic condition that affects liver function. The index case, the 18-year-old asymptomatic brother of a young man recently diagnosed with Wilson disease, presented for Wilson disease screening and was also found to have abnormal liver function suggestive of cholestasis. However, ceruloplasmin level, 24 h urine copper concentration and liver synthetic function were normal. Further hepatic investigations and genetic mutation analysis were performed, ultimately leading to a diagnosis of Alagille syndrome. He was treated with ursodiol, which resulted in normalization of his liver function tests. Subsequently, he was found to be a carrier for a mutation in the Wilson disease gene, ATP7B. In the present report, the potential implications of being a heterozygote for Wilson disease in the context of Alagille syndrome are discussed. Also stressed is that care must be exercised by the clinician when diagnosing family members who may present with two different disorders closely mimicking one another.

  3. HFE gene mutations and Wilson's disease in Sardinia.

    Science.gov (United States)

    Sorbello, Orazio; Sini, Margherita; Civolani, Alberto; Demelia, Luigi

    2010-03-01

    Hypocaeruloplasminaemia can lead to tissue iron storage in Wilson's disease and the possibility of iron overload in long-term overtreated patients should be considered. The HFE gene encodes a protein that is intimately involved in intestinal iron absorption. The aim of this study was to determine the prevalence of the HFE gene mutation, its role in iron metabolism of Wilson's disease patients and the interplay of therapy in copper and iron homeostasis. The records of 32 patients with Wilson's disease were reviewed for iron and copper indices, HFE gene mutations and liver biopsy. Twenty-six patients were negative for HFE gene mutations and did not present significant alterations of iron metabolism. The HFE mutation was significantly associated with increased hepatic iron content (Pgene wild-type. The HFE gene mutations may be an addictional factor in iron overload in Wilson's disease. Our results showed that an adjustment of dosage of drugs could prevent further iron overload induced by overtreatment only in patients HFE wild-type. 2009. Published by Elsevier Ltd.

  4. Are scattering amplitudes dual to super Wilson loops?

    CERN Document Server

    Belitsky, A V; Sokatchev, E

    2012-01-01

    The MHV scattering amplitudes in planar N=4 SYM are dual to bosonic light-like Wilson loops. We explore various proposals for extending this duality to generic non-MHV amplitudes. The corresponding dual object should have the same symmetries as the scattering amplitudes and be invariant to all loops under the chiral half of the N=4 superconformal symmetry. We analyze the recently introduced supersymmetric extensions of the light-like Wilson loop (formulated in Minkowski space-time) and demonstrate that they have the required symmetry properties at the classical level only, up to terms proportional to field equations of motion. At the quantum level, due to the specific light-cone singularities of the Wilson loop, the equations of motion produce a nontrivial finite contribution which breaks some of the classical symmetries. As a result, the quantum corrections violate the chiral supersymmetry already at one loop, thus invalidating the conjectured duality between Wilson loops and non-MHV scattering amplitudes. W...

  5. BOOK REVIEW: Democracy and Political Life in Nigeria | Wilson ...

    African Journals Online (AJOL)

    In this review of Victor Dike's book - \\"Democracy and Political Life in Nigeria\\", Inam Wilson underscores the author's attempts to draw a connection between Nigeria's chequered political history and her present economic trajectory to explain why Nigeria is today facing numerous sociopolitical and economic challenges, ...

  6. Middle-aged heterozygous carriers of Wilson's disease do not ...

    Indian Academy of Sciences (India)

    or infectious disease were excluded), were chosen as control subjects (CS). All WDHzc were subjected to neurological examination. They were questioned about history of any liver. Keywords. autosomal recessive; ATP7B; copper; heterozygous carrier; phenotype; Wilson's disease. Journal of Genetics, Vol. 89, No.

  7. Municipal Broadband in Wilson, North Carolina: A Study

    Science.gov (United States)

    O'Boyle, Timothy

    2012-01-01

    Relatively little empirical attention has been paid to the political economy of publicly-retailed fiber-optic broadband internet service. To address this gap in the literature, this dissertation examines the history, dynamics and trends in the municipal broadband movement. In specific, Wilson, North Carolina's Greenlight service is examined in…

  8. String theory duals of Wilson loops from Higgsing

    Science.gov (United States)

    Lietti, Marco; Mauri, Andrea; Penati, Silvia; Zhang, Jia-ju

    2017-08-01

    For three-dimensional ABJ(M) theories and N=4 Chern-Simons-matter quiver theories, we construct two sets of 1/2 BPS Wilson loop operators by applying the Higgsing procedure along independent directions of the moduli space, and choosing different massive modes. For theories whose dual M-theory description is known, we also determine the corresponding spectrum of 1/2 BPS M2-brane solutions. We identify the supercharges in M-theory and field theory, as well as the supercharges preserved by M2-/anti-M2-branes and 1/2 BPS Wilson loops. In particular, in N=4 orbifold ABJM theory we find pairs of different 1/2 BPS Wilson loops that preserve exactly the same set of supercharges. In field theory they arise by Higgsing with the choice of either particles or antiparticles, whereas in the dual description they correspond to a pair of M2-/anti-M2-branes localized at different positions in the compact space. This result enlightens the origin of classical Wilson loop degeneracy in these theories, already discussed in arXiv:1506.07614. A discussion on possible scenarios that emerge by comparison with localization results is included.

  9. Anaemia and blood transfusion in the ICU | Wilson | Southern ...

    African Journals Online (AJOL)

    Southern African Journal of Critical Care. Journal Home · ABOUT · Advanced Search · Current Issue · Archives · Journal Home > Vol 20, No 1 (2004) >. Log in or Register to get access to full text downloads. Username, Password, Remember me, or Register. Anaemia and blood transfusion in the ICU. GS Wilson. Abstract.

  10. A Ramanujan-type measure for the Askey-Wilson polynomials

    Science.gov (United States)

    Atakishiyev, Natig M.

    1995-01-01

    A Ramanujan-type representation for the Askey-Wilson q-beta integral, admitting the transformation q to q(exp -1), is obtained. Orthogonality of the Askey-Wilson polynomials with respect to a measure, entering into this representation, is proved. A simple way of evaluating the Askey-Wilson q-beta integral is also given.

  11. Wilson's Panchreston: the inclusive fitness hypothesis of sociobiology re-examined.

    Science.gov (United States)

    Dickemann, M

    1995-01-01

    Of several hypotheses proposed by sociobiologists to explain "homosexuality", the most widely discussed is the inclusive fitness hypothesis, which is examined here in the work of the primary sociobiological proponents, E. O. Wilson, Michael Ruse, and James Weinrich. After reviewing the basic evolutionary concepts of natural selection, adaptation, and inclusive fitness/kin selection, I analyze the inclusive fitness hypotheses of homosexuality, taking as an exemplar the initial statement of E. O. Wilson. The implicit assumptions is this hypothesis are identified: that "homosexuality" is a unitary phenomenon, of direct genetic origin, occurring at similar frequencies across societies and through time, without direct reproductive gain, with therefore must be of genetic advantage to relatives. Each of these implicit assumptions is discussed and assessed in turn. The inclusive fitness hypothesis, derived primarily from current stereotypes about homosexuals in Western society, is found to be misconceived and without scientific merit. A general discussion of the nature-nurture, or essentialist-social-constructionist, controversy as it involves this hypothesis concludes the essay.

  12. Lectures on probability and statistics

    Energy Technology Data Exchange (ETDEWEB)

    Yost, G.P.

    1984-09-01

    These notes are based on a set of statistics lectures delivered at Imperial College to the first-year postgraduate students in High Energy Physics. They are designed for the professional experimental scientist. We begin with the fundamentals of probability theory, in which one makes statements about the set of possible outcomes of an experiment, based upon a complete a priori understanding of the experiment. For example, in a roll of a set of (fair) dice, one understands a priori that any given side of each die is equally likely to turn up. From that, we can calculate the probability of any specified outcome. We finish with the inverse problem, statistics. Here, one begins with a set of actual data (e.g., the outcomes of a number of rolls of the dice), and attempts to make inferences about the state of nature which gave those data (e.g., the likelihood of seeing any given side of any given die turn up). This is a much more difficult problem, of course, and one's solutions often turn out to be unsatisfactory in one respect or another.

  13. The Oskar Klein Memorial Lectures

    CERN Document Server

    1991-01-01

    The Oskar Klein Memorial Lectures, instituted in 1988 and supported by the Royal Swedish Academy of Sciences through its Nobel Committee for Physics, are given at Stockholm University in Sweden, where Oskar Klein was professor in Theoretical Physics 1930-1962.Volume 1 contains the 1988 lectures on "Symmetry and Physics" and "From the Bethe-Hulthén Hypothesis to the Yang-Baxter Equation," given by C N Yang, Nobel Prize winner (1957) and professor at the State University of New York at Stony Brook. The 1989 lectures on "Beyond the Standard Models," referring to models for cosmology and elementar

  14. John Adams Lecture

    CERN Multimedia

    PH Department

    2010-01-01

    13 December 2010 14:30 - Council Chamber, Bldg.503-1-001 Accelerator Breakthroughs, Achievements and Lessons from the Tevatron Collider V. Shiltsev / Fermilab’s Accelerator Physics Centre This year we celebrate the 25th anniversary of the first proton-antiproton collisions in the Tevatron. For two and a half decades the Tevatron at Fermilab (Batavia, IL, USA) was a centerpiece of the US and world’s High Energy Physics as the world’s highest energy particle collider at 1.8 TeV center of mass energy. While funding agencies are deciding on a 3-year extension of the Collider Run II operation through 2014, we – in this 2010 John Adams Lecture - will take a look in exciting story of the Tevatron: the story of long preparations, great expectations, numerous difficulties, years of “blood and sweat”, continuous upgrades, exceeding original goals (by a factor of 400) and high emotions. An accelerator scientist prospective will be given on a wide spectrum o...

  15. SUMMER STUDENT LECTURE PROGRAMME

    CERN Multimedia

    Academic Training; Tel. 73127

    2001-01-01

    Main Auditorium bldg. 500 Date Time Lecturer Title Monday 30 July 9:15 10:15 11:15 G. Guidice / CERN T. Nakada / CERN P. Wells / CERN Beyond the Standard Model (1/3) Violation of Particle Anti-particle Symmetry (3/3) LEP Physics (3/4) Tuesday 31 July 9:15 10:15 11:15 G. Guidice / CERN F. Dydak / CERN P. Wells / CERN P. Lebrun / CERN P. Lebrun / CERN Beyond the Standard Model (2/3) Neutrino Physics (1/4) LEP Physics (4/4) Superconducting Technology for particle accelerators (1/2) Superconducting Technology for particle accelerators (2/2) Wednesday 1 August 9:15 10:15 11:15 G. Guidice / CERN F. Dydak / CERN G. Guidice; P. Wells G. Guidice in main auditorium, P. Wells in TH auditorium) O. Grobner / CERN O. Grobner / CERN Beyond the Standard Model (3/3) Neutrino Physics (2/4) Discussion Session Ultra High Vacuum Technology (1/2) Ultra High Vacuum Technology (2/2) Thursday 2 August 9:15 10:15 11:15 F. Antinori / CERN F. Dydak / CERN J. Aysto / CERN Heavy Ions (1/2) Neutrino Physics (3/4) Isolde Physics O...

  16. ACADEMIC TRAINING LECTURE

    CERN Multimedia

    Academic Training; Tel. 73127

    2002-01-01

    14, 15, 16, 17, 18 January LECTURE SERIES From 11:00 hrs - Auditorium, bldg 500 Superconducting materials suitable for magnets D.C. Larbalestier / Univ. of Wisconsin, USA The range of materials available for superconducting magnets is steadily expanding, even as the choice of material becomes potentially more complex. When virtually all magnets were cooled by helium at ~2-5 K it was easy to separate the domain of Nb-Ti from those of Nb3Sn applications and very little surprise that more than 90% of all magnets are still made from Nb-Ti. But the development of useful conductors of the Bi-Sr-Ca-Cu-O and YBa2Cu3Ox high temperature superconductors, coupled to the recent discovery of the 39 K superconductor MgB2 and the developing availability of cryocoolers suggests that new classes of higher temperature, medium field magnets based on other than Nb-based conductors could become available in the next 5-10 years. My talks will discuss the essential physics and materials science of these 5 classes of material - Nb-Ti...

  17. ACADEMIC TRAINING LECTURE

    CERN Multimedia

    Academic Training; Tel. 73127

    2001-01-01

    14, 15, 16, 17, 18 January LECTURES FOR POSTGRADUATE STUDENTS From 11:00 hrs - Auditorium, bldg 500 Superconducting materials suitable for magnets D.C. Larbalestier / Univ. of Wisconsin, USA The range of materials available for superconducting magnets is steadily expanding, even as the choice of material becomes potentially more complex. When virtually all magnets were cooled by helium at ~2-5 K it was easy to separate the domain of Nb-Ti from those of Nb3Sn applications and very little surprise that more than 90% of all magnets are still made from Nb-Ti. But the development of useful conductors of the Bi-Sr-Ca-Cu-O and YBa2Cu3Ox high temperature superconductors, coupled to the recent discovery of the 39 K superconductor MgB2 and the developing availability of cryocoolers suggests that new classes of higher temperature, medium field magnets based on other than Nb-based conductors could become available in the next 5-10 years. My talks will discuss the essential physics and materials science of these 5 classes...

  18. ACADEMIC TRAINING LECTURE

    CERN Multimedia

    Academic Training; Tel. 73127

    2001-01-01

    27, 28, 29 June and 2, 3 July REGULAR LECTURE PROGRAMME From 11:00 hrs - Council Chamber bldg. 503 on 27, 28, 29 June and Auditorium, bldg 500 on 2, 3 July Particle Identification at the LHC P. Eerola / Lund University, SE The LHC experiments will explore new frontiers of particle physics. To maximize the physics potential of LHC, we need identification of leptons, hadrons, photons and 'invisible' particles. This is realized through reconstruction of electrons and muons, charged particle tracking and identification, b- and tau-tagging, and jet reconstruction. In addition, missing energy has to be measured in order to look for signatures of invisible particles. The experimental conditions posed by the collider, which will be operating at higher energy and luminosity than the present ones, are demanding. A large dynamical range is required in order to measure energies and momenta ranging from below one GeV to several TeVs. The detectors should be able to cope with the 40 MHz collision rate, with a large number ...

  19. SUMMER STUDENT LECTURE PROGRAMME

    CERN Multimedia

    Academic Training; Tel. 73127

    2001-01-01

    Main Auditorium bldg. 500 Date Time Lecturer Title Wednesday 4 July 9:15 10:15 11:15 14:00 15:00 15:45 L. Maiani / CERN L. Maiani / CERN M. Franklin / CERN G. Stevenson M. Diemoz O. Ullaland Introduction to CERN & Particle Physics (1/2) Introduction to CERN & Particle Physics (2/2) Classic Experiments (1/3) CERN Radiation Protection CERN Information on Activities CERN Intro to workshops Thursday 5 July 9:15 10:15 11:15 14:00 15:00 16:30 M. Franklin / CERN M. Franklin / CERN M. Franklin / CERN F. Close F. Close   Classic Experiments (2/3) Classic Experiments (3/3) Discussion session Particle Physics (for non-physics students) (1/4) Particle Physics (for non-physics students) (2/4) Welcome Drink Friday 6 July 9:15 10:15 F. Close F. Close Particle Physics (for non-physics students) (3/4) Particle Physics (for non-physics students) (4/4) Monday 9 July 9:15 10:15 11:15 R. Kleiss / CERN L. Rolandi / CERN L. Rolandi / CERN Fundamental Concepts of Particle Physics (1/6) Big Experime...

  20. SUMMER STUDENT LECTURE PROGRAMME

    CERN Multimedia

    Academic Training; Tel. 73127

    2001-01-01

    Main Auditorium bldg. 500 Date Time Lecturer Title Monday 9 July 9:15 10:15 11:15 R. Kleiss / CERN L. Rolandi / CERN L. Rolandi / CERN Fundamental Concepts of Particle Physics (1/6) Big Experiments Discussion Session Tuesday 10 July 9:15 10:15 11:15 R. Kleiss / CERN R. Kleiss / CERN C. Joram Fundamental Concepts of Particle Physics (2/6) Fundamental Concepts of Particle Physics (3/6) Particle Detectors (1/5) Wednesday 11 July 9:15 10:15 11:15 R. Kleiss / CERN C. Joram / CERN R. Kleiss / C. Joram Fundamental Concepts of Particle Physics (4/6) Particle Detectors (2/5) Discussion Session Thursday 12 July 9:15 10:15 11:15 R. Kleiss / CERN C. Joram / CERN C. Joram / CERN Fundamental Concepts of Particle Physics (5/6) Particle Detectors (3/5) Particle Detectors (4/5) Friday 13 July 9:15 10:15 11:15 R. Kleiss / CERN C. Joram / CERN R. Kleiss / C. Joram Fundamental Concepts of Particle Physics (6/6) Particle Detectors (5/5) Discussion Session Monday 16 July 9:15 10:15 11:15 A. Pich O. Brüning C...

  1. SUMMER STUDENT LECTURE PROGRAMME

    CERN Multimedia

    Françoise Benz

    2002-01-01

    Main Auditorium, bldg. 500   DATE TIME LECTURER TITLE Monday 22 July 09:15 - 10:00 A. PICH Standard Model (6/8) 10:15 - 11:00 J. CARR  Astroparticles (1/3) 11:15 - 12:00 J. SHIERS Computing (1/3) Tuesday 23 July 09:15 - 10:00 A. PICH Standard Model (7/8) 10:15 - 11:00 J. CARR  Astroparticles (2/3) 11:15 - 12:00 J. SHIERS Computing (2/3) Wednesday 24July 09:15 - 10:00 A. PICH Standard Model (8/8) 10:15 - 11:00 J. CARR  Astroparticles (3/3) 11:15 - 12:00 Discussion Session 14:00 - 16:00 O. GROBNER UHV Technology Thursday 25 July (Theory Auditorium) 09:15 - 10:00 R. RATTAZZI Beyond the Standard Model (1/3) (TH) 10:15 - 11:00 P. WELLS Experimental test of the SM - LEP (1/3) (TH) 11:15 - 12:00 J. SHIERS Computing (3/3) (TH) Friday 26 July 09:15 - 10:00 R. RATTAZZI Beyond the Standard Model (2/3) 10:15 - 11:00 P. WELLS Experimental test of the SM - LEP (2/3) 11:15 - 12:00 Discussion Session Monday 29 July 09:15 - 10:00  R...

  2. SUMMER STUDENT LECTURE PROGRAMME

    CERN Multimedia

    Academic Training; Tel. 73127

    2001-01-01

    Main Auditorium bldg. 500 Date Time Lecturer Title Monday 6 August 9:15 10:15 11:15 F. Gianotti / CERN J. Carr / CERN E. Copeland / Centre for Theoretical Physics University of Sussex, UK LHC Physics (1/3) Astroparticle Physics (1/3) Introduction to Cosmology (1/2) Tuesday 7 August 9:15 10:15 11:15 14:00 15:00 F. Gianotti / CERN J. Carr / CERN E. Copeland / Centre for Theoretical Physics University of Sussex, UK LHC Physics (2/3) Astroparticle Physics (2/3) Introduction to Cosmology (2/2) Wednesday 8 August 9:15 10:15 11:15 14:00 15:00 F. Gianotti / CERN J. Carr / CERN J. Carr; F. Gianotti J. Carr in main auditorium F. Gianotti in TH auditorium LHC Physics (2/3) Astroparticle Physics (2/3) Discussion Session Thursday 9 August 9:15 10:15 11:15 G. Veneziano / CERN G. Veneziano; E. Copeland G. Veneziano in main auditorium E. Copeland in TH auditorium Dreams of a Finite Theory (1/2) Student Session (1/3) Discussion Session Friday 10 August 9:15 10:15 11:15 G. Veneziano / CERN L. Okun / CERN Student Se...

  3. Lectures on general relativity

    CERN Document Server

    Papapetrou, Achille

    1974-01-01

    This book is an elaboration of lecture notes for the graduate course on General Rela­ tivity given by the author at Boston University in the spring semester of 1972. It is an introduction to the subject only, as the time available for the course was limited. The author of an introduction to General Relativity is faced from the beginning with the difficult task of choosing which material to include. A general criterion as­ sisting in this choice is provided by the didactic character of the book: Those chapters have to be included in priority, which will be most useful to the reader in enabling him to understand the methods used in General Relativity, the results obtained so far and possibly the problems still to be solved. This criterion is not sufficient to ensure a unique choice. General Relativity has developed to such a degree, that it is impossible to include in an introductory textbook of a reasonable length even a very condensed treatment of all important problems which have been discussed unt...

  4. Public Lectures | Events | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Public and special lectures in Mid-Year and Annual Meetings. Academy Public Lectures · Public and special lectures in Mid-Year and Annual Meetings · Platinum Jubilee Lectures. Single molecule spectroscopy of a single live cell. Kankan Bhattacharyya Pune, 8 November 2015 (81st Annual Meeting). Pulse to planet: ...

  5. [Lecturing--an enduring teaching method].

    Science.gov (United States)

    Eika, Berit; Wichmann-Hansen, Gitte; Høyer, Christian S; Mørcke, Anne Mette

    2008-10-27

    Lecturing is one of the oldest forms of teaching. The lecture is as effective as other teaching formats for transmitting information. One of the major defects of the lecture method is that it tends to induce passive learning. In order to lecture effectively, the lecturer must gain and hold the attention of the audience. Also, the audience should be given a chance to elaborate on the information presented. The list of expedient lecturing skills is long. In this paper we focus on how to effectively open and close a lecture. In addition, we give suggestions to how an audience may be actively engaged.

  6. Exact results for Wilson loops in arbitrary representations

    Energy Technology Data Exchange (ETDEWEB)

    Fiol, Bartomeu; Torrents, Genís [Departament de Física Fonamental i Institut de Ciències del Cosmos, Universitat de Barcelona,Martí i Franquès 1, 08028 Barcelona, Catalonia (Spain)

    2014-01-08

    We compute the exact vacuum expectation value of 1/2 BPS circular Wilson loops of N=4 U(N) super Yang-Mills in arbitrary irreducible representations. By localization arguments, the computation reduces to evaluating certain integrals in a Gaussian matrix model, which we do using the method of orthogonal polynomials. Our results are particularly simple for Wilson loops in antisymmetric representations; in this case, we observe that the final answers admit an expansion where the coefficients are positive integers, and can be written in terms of sums over skew Young diagrams. As an application of our results, we use them to discuss the exact Bremsstrahlung functions associated to the corresponding heavy probes.

  7. Unusual imaging findings in Wilson's disease

    Energy Technology Data Exchange (ETDEWEB)

    Akhan, Okan; Akpinar, Erhan; Oto, Aytekin; Koeroglu, Mert; Oezmen, Mustafa N.; Akata, Deniz [Department of Radiology, Hacettepe University, Sihhiye/Ankara (Turkey); Bijan, Bijan [Abdominal Imaging/MR and Nonvascular Interventional Division, University of California, Davis, California (United States)

    2002-07-01

    We present unusual imaging findings in the liver of a patient with Wilson's disease. On US, the liver contours were irregular and its echogenicity was increased with multiple, small hypo- and hyperechoic nodules. Prominent perihepatic fat layer was noted to be increased in thickness. On CT and MR, multiple, small, enhancing nodules were detected in the liver in the early arterial phase after administration of intravenous contrast material. Biopsy was consistent with chronic parenchymal liver pathology with dysplastic changes but without evidence of hepatocellular carcinoma. To our knowledge, dysplastic nodules enhancing at the arterial phase and thickened perihepatic fat layer have not been previously reported in patients with Wilson's disease. (orig.)

  8. Improved quasi parton distribution through Wilson line renormalization

    Energy Technology Data Exchange (ETDEWEB)

    Chen, Jiunn-Wei [Department of Physics, Center for Theoretical Sciences, and Leung Center for Cosmology and Particle Astrophysics, National Taiwan University, Taipei, 106, Taiwan (China); Center for Theoretical Physics, Massachusetts Institute of Technology, Cambridge, MA 02139 (United States); Ji, Xiangdong [INPAC, Department of Physics and Astronomy, Shanghai Jiao Tong University, Shanghai, 200240 (China); Maryland Center for Fundamental Physics, Department of Physics, University of Maryland, College Park, MD 20742 (United States); Zhang, Jian-Hui, E-mail: jianhui.zhang@physik.uni-regensburg.de [Institut für Theoretische Physik, Universität Regensburg, D-93040 Regensburg (Germany)

    2017-02-15

    Recent developments showed that hadron light-cone parton distributions could be directly extracted from spacelike correlators, known as quasi parton distributions, in the large hadron momentum limit. Unlike the normal light-cone parton distribution, a quasi parton distribution contains ultraviolet (UV) power divergence associated with the Wilson line self energy. We show that to all orders in the coupling expansion, the power divergence can be removed by a “mass” counterterm in the auxiliary z-field formalism, in the same way as the renormalization of power divergence for an open Wilson line. After adding this counterterm, the quasi quark distribution is improved such that it contains at most logarithmic divergences. Based on a simple version of discretized gauge action, we present the one-loop matching kernel between the improved non-singlet quasi quark distribution with a lattice regulator and the corresponding quark distribution in dimensional regularization.

  9. New supersymmetric Wilson loops in ABJ(M) theories

    Energy Technology Data Exchange (ETDEWEB)

    Cardinali, V., E-mail: cardinali@fi.infn.it [Dipartimento di Fisica, Universita di Firenze and INFN Sezione di Firenze, Via G. Sansone 1, 50019 Sesto Fiorentino (Italy); Griguolo, L., E-mail: griguolo@fis.unipr.it [Dipartimento di Fisica, Universita di Parma and INFN Gruppo Collegato di Parma, Viale G.P. Usberti 7/A, 43100 Parma (Italy); Martelloni, G., E-mail: martelloni@fi.infn.it [Dipartimento di Fisica, Universita di Firenze and INFN Sezione di Firenze, Via G. Sansone 1, 50019 Sesto Fiorentino (Italy); Seminara, D., E-mail: seminara@fi.infn.it [Dipartimento di Fisica, Universita di Firenze and INFN Sezione di Firenze, Via G. Sansone 1, 50019 Sesto Fiorentino (Italy)

    2012-12-05

    We present two new families of Wilson loop operators in N=6 supersymmetric Chern-Simons theory. The first one is defined for an arbitrary contour on the three dimensional space and it resembles the Zarembo construction in N=4 SYM. The second one involves arbitrary curves on the two dimensional sphere. In both cases one can add certain scalar and fermionic couplings to the Wilson loop so it preserves at least two supercharges. Some previously known loops, notably the 1/2 BPS circle, belong to this class, but we point out more special cases which were not known before. They could provide further tests of the gauge/gravity correspondence in the ABJ(M) case and interesting observables, exactly computable by localization techniques.

  10. Chromosomenindividualität or Entmischung? The debate between Paolo Della Valle and Edmund B. Wilson.

    Science.gov (United States)

    Volpone, Alessandro

    2015-01-01

    At the beginning of the twentieth century, the Italian cytologist Paolo Della Valle developed a theory of instable chromosomes (teoria dei cromosomi labili). He radically criticized the so-called Sutton-Boveri hypothesis (Martins and Martins, Genetics and Molecular Biology, 22:261-271, 1999), focusing on numerical constancy in the species and individuality. On the basis of bibliographical review and personal observations, he maintained that the chromosomes were neither stable bodies, nor permanent structures, but transitory cellular materials, resulting from the periodical rearrangement of the chromatin during the cell division. German and English-speaking biologists reacted. The paper shows some content of the argumentations used by Thomas H. Montgomery and especially Edmund B. Wilson. The discussion was characterized by the same data which is interpretedby different scholars in different ways. And the point is that no one of them had the decisive test to demonstrate his own point of view. Wilson simply invoked on his behalf a certain 'common sense', defending at least a 'high degree of constancy'. The debate waned along with the reception of Morgan's chromosome theory of heredity, but only the advent of molecular biology definitively stated the nature of chromosomes as permanent structures of the cell.

  11. Chiral symmetry on the lattice with Wilson fermions

    Energy Technology Data Exchange (ETDEWEB)

    Bochicchio, M.; Maiani, L.; Martinelli, G.; Rossi, G.; Testa, M.

    1985-12-16

    The chiral properties of the continuum limit of lattice QCD with Wilson fermions are studied. We show that a partially conserved axial current can be defined, satisfying the usual current algebra requirements. A proper definition of the chiral symmetry order parameter, <0 vertical stroke anti psi psi vertical stroke 0>, is given, and the chiral properties of composite operators are investigated. The implications of our analysis to the lattice determination of non-leptonic weak amplitudes are also discussed. (orig.).

  12. Wilson's disease: an analysis of 28 Brazilian children

    Directory of Open Access Journals (Sweden)

    Rodolpho Truffa Kleine

    2012-01-01

    Full Text Available OBJECTIVES: Clinical-laboratory and evolutionary analysis of twenty-eight patients with Wilson's disease. METHODS: Twenty-eight children (twelve females and sixteen males with Wilson's disease were evaluated retrospectively between 1987 and 2009, with a follow-up of 72 months (1 - 240 months. The clinical, laboratory, and histologic features at diagnosis were recorded at the end of the study. RESULTS: The median age at diagnosis was 11 years (2 - 18 years. Twelve patients were asymptomatic, seven had hepatitis symptoms, five had raised aminotransferase levels, three had hepatomegaly associated with neurological disorders, one had fulminant hepatitis with hemolytic anemia, and six patients presented with a Kayser-Fleischer ring. A histological analysis revealed that six children had chronic hepatitis, seven had cirrhosis, two had steatosis, one had portal fibrosis, and one had massive necrosis. The treatment consisted of D-penicillamine associated with pyridoxine for 26 patients. Adverse effects were observed in the other two patients: one presented with uncontrollable vomiting and the other demonstrated elastosis perforans serpiginosa. At the end of the study, all 26 treated patients were asymptomatic. Twenty-four of the patients were treated with D-penicillamine and pyridoxine, and two were treated with trientine and zinc sulfate. A liver transplant was performed in one patient with fulminant hepatitis, but the final patient died 48 hours after admission to the intensive care unit. CONCLUSIONS: Family screenings associated with early treatment are important in preventing Wilson's disease symptoms and potentially fatal disease progression. The study suggests that Wilson's disease must be ruled out in children older than two years presenting with abnormal levels of hepatic enzymes because of the heterogeneity of symptoms and the encouraging treatment results obtained so far.

  13. Wilson Martins: between the intelligentsia and the university (1951

    Directory of Open Access Journals (Sweden)

    Névio de Campos

    2012-05-01

    Full Text Available Abstract The purpose of this article is to analyze the presence of Ortega y Gasset in the Parana’s State group during the 1950s, especially his influence in the thinking of Wilson Martins, and to emphasize the debate on the ideas of the intellectual and the university. The article discusses about the contributions of this Parana’s thinker on the Parana’s university teaching constituting and organizing process, and emphasizes that the Wilson Martins’ role consisted in promoting the debate on the presence of the intellectual person in modern society, attributing the mission as guardian of the moral and herald of cultural renovation, without forgetting the Brazilian and European political-cultural context as the founding background to higher education. It bases itself on the speech entitled “The rebellion against intelligence and the mission of the university”, that occurred at the University of Parana in 1951, and on the work The History of Brazilian Intelligence, written by Wilson Martins.

  14. The epsilon regime with twisted mass Wilson fermions

    CERN Document Server

    Bar, Oliver; Shindler, Andrea

    2010-01-01

    We investigate the leading lattice spacing effects in mesonic two-point correlators computed with twisted mass Wilson fermions in the epsilon-regime. By generalizing the procedure already introduced for the untwisted Wilson chiral effective theory, we extend the continuum chiral epsilon expansion to twisted mass WChPT. We define different regimes, depending on the relative power counting for the quark masses and the lattice spacing. We explicitly compute, for arbitrary twist angle, the leading O(a^2) corrections appearing at NLO in the so-called GSM^* regime. As in untwisted WChPT, we find that in this situation the impact of explicit chiral symmetry breaking due to lattice artefacts is strongly suppressed. Of particular interest is the case of maximal twist, which corresponds to the setup usually adopted in lattice simulations with twisted mass Wilson fermions. The formulae we obtain can be matched to lattice data to extract physical low energy couplings, and to estimate systematic uncertainties coming from ...

  15. [Wilson disease. A case report and review of the literature].

    Science.gov (United States)

    Alva-Moncayo, Edith; Castro-Tarín, María; González-Serrano, Adolfo

    2011-01-01

    Wilson disease is a problem of cuprum metabolism, with recesive autosomic hereditary transmission and a prevalence of one in 30,000 habitants. The cuprum is deposit in a progressive and irreversible way in the liver and encephalus and it is not liberated with quelant treatment. Neurological manifestations are tremor, disartria, extrapiramidal manifestations or distonia. Ophthalmic exploration shows corneal limb with sign of Kayser-Fleischer. a 15-year-old masculine patient with previous hepatitis outbreak in two times. During the last year he presented distonia, bradicinecious, stiffness and indifference with ictericia. Ophthalmological examination reported Kayser-Fleisher rings. Magnetic resonance of brain showed high dense images in lenticular, pallidus globe and caudate nucleus suggestive of Wilson disease. Ceruloplasmin concentration, cuprum in the liver biopsy confirmed the diagnosis. the importance of the case was the hepatic initial manifestations and two years after presented with inexpressive face, and it was considered a psychiatric disease, but the neurological evaluation and the liver biopsy confirmed the diagnosis of Wilson disease.

  16. Exploring medical student decisions regarding attending live lectures and using recorded lectures.

    Science.gov (United States)

    Gupta, Anmol; Saks, Norma Susswein

    2013-09-01

    Student decisions about lecture attendance are based on anticipated effect on learning. Factors involved in decision-making, the use of recorded lectures and their effect on lecture attendance, all warrant investigation. This study was designed to identify factors in student decisions to attend live lectures, ways in which students use recorded lectures, and if their use affects live lecture attendance. A total of 213 first (M1) and second year (M2) medical students completed a survey about lecture attendance, and rated factors related to decisions to attend live lectures and to utilize recorded lectures. Responses were analyzed overall and by class year and gender. M1 attended a higher percentage of live lectures than M2, while both classes used the same percentage of recorded lectures. Females attended more live lectures, and used a smaller percentage of recorded lectures. The lecturer was a key in attendance decisions. Also considered were the subject and availability of other learning materials. Students use recorded lectures as replacement for live lectures and as supplement to them. Lectures, both live and recorded, are important for student learning. Decisions about lecture placement in the curriculum need to be based on course content and lecturer quality.

  17. A Study of the Use of Twitter by Students for Lecture Engagement and Discussion

    Science.gov (United States)

    Tiernan, Peter

    2014-01-01

    Research indicates that student engagement with lectures, and participation in discussion and debate, greatly improve their learning and experience of University. The nature of some lectures means they can lack opportunities for interaction and active learning. For this reason it can be difficult for some students, especially students new to…

  18. The Mount Wilson-University of California Connection from Hussey and Seares to Mayall and Olin Wilson

    Science.gov (United States)

    Osterbrock, D. E.

    2004-12-01

    George Ellery Hale, who founded Mount Wilson Solar Observatory, first visited Lick Observatory in 1890, soon after his graduation from MIT. After his parents' deaths, when he began openly planning a Yerkes Observatory ``expedition" to California, Hale's friend James E. Keeler, then Lick Observatory Director, invited him (in 1899) to locate it on Mt.Hamilton. Hale thanked him, but replied that sites further south would have more clear weather. He had probably already decided on Mount Wilson. There were many close connections between the University of California and Mount Wilson Observatory from that time right up to the present. W.J. Hussey was the Lick astronomer who carried out the official site survey that confirmed Mount Wilson as the best site. Harold Palmer (UC Astronomy PhD 1903) was the first new staff member Hale hired, but he only lasted a few months. The two main reasons for the continuing connection were the geographical proximity of Pasadena and the Bay Area, and the fact that for many years UC was the outstanding graduate astronomy department in the country, producing numerous well trained observational research astronomers. However in the early years the reasons were more complicated. After Palmer, the next three hired at MWO were Arthur King, the first UC Physics PhD (1903); Harold Babcock, (UC Engineering BS 1907); and F.H. Seares (UC Astronomy BS 1895). Harold Babcock trained his son in astronomy almost from birth, and Horace (UC Astronomy PhD 1938) joined the MWO staff after World War II and became its Director in 1964. Palmer and Edward Fath (UC PhD 1909) were less successful at MWO and soon departed. These and numerous other MWO astronomers with UC backgrounds will be mentioned, and their careers discussed.

  19. Practical strategies for effective lectures.

    Science.gov (United States)

    Lenz, Peter H; McCallister, Jennifer W; Luks, Andrew M; Le, Tao T; Fessler, Henry E

    2015-04-01

    Lecturing is an essential teaching skill for scientists and health care professionals in pulmonary, critical care, and sleep medicine. However, few medical or scientific educators have received training in contemporary techniques or technology for large audience presentation. Interactive lecturing outperforms traditional, passive-style lecturing in educational outcomes, and is being increasingly incorporated into large group presentations. Evidence-based techniques range from the very simple, such as inserting pauses for audience discussion, to more technologically advanced approaches such as electronic audience response systems. Alternative software platforms such as Prezi can overcome some of the visual limits that the ubiquitous PowerPoint imposes on complex scientific narratives, and newer technology formats can help foster the interactive learning environment. Regardless of the technology, adherence to good principles of instructional design, multimedia learning, visualization of quantitative data, and informational public speaking can improve any lecture. The storyline must be clear, logical, and simplified compared with how it might be prepared for scientific publication. Succinct outline and summary slides can provide a roadmap for the audience. Changes of pace, and summaries or other cognitive breaks inserted every 15-20 minutes can renew attention. Graphics that emphasize clear, digestible data graphs or images over tables, and simple, focused tables over text slides, are more readily absorbed. Text slides should minimize words, using simple fonts in colors that contrast to a plain background. Adherence to these well-established principles and addition of some new approaches and technologies will yield an engaging lecture worth attending.

  20. Lectures in synergetics

    CERN Document Server

    Sugakov, Volodymyr I

    1998-01-01

    The world that surrounds us is a complex system of interacting objects. The versatility of the links and interactions brings about the infinite multiplicity of natural phenomena. "Synergetics" studies nonlinear nonequilibrium processes and self-organization phenomena, allowing for description, systematization and generalization of the phenomena that are described by the different branches of natural science: physics, chemistry, biology, as well as sociology and economics. This book introduces the reader to the exciting world of the nonlinear phenomena that are studied in synergetics. The book

  1. Exploring first year students' and their lecturers' constructions of ...

    African Journals Online (AJOL)

    and purpose of reading, and those implicitly accepted as normative by their lecturers. It accounted for the students' difficulties in achieving epistemological access in terms of a conflict of frames: both the students and their teachers failed to recognise each others' constructions about the nature and purpose of `reading for

  2. Eight lectures on theoretical physics

    CERN Document Server

    Planck, Max

    1997-01-01

    In 1909 the great German physicist and Nobel Prize winner Max Planck (1858-1947) delivered a series of eight lectures at Columbia University giving a fascinating overview of the new state of physics, which he had played a crucial role in bringing about. The first, third, fifth, and sixth lectures present his account of the revolutionary developments occasioned when he first applied the quantum hypothesis to blackbody radiation. The reader is given an invaluable opportunity to witness Planck's thought processes both on the level of philosophical principles as well as their application to physi

  3. CFN lectures on functional nanostructures

    CERN Document Server

    Vojta, Matthias; Schön, Gerd

    2011-01-01

    This series of books contains selected and edited lectures from summer schools organized by the Center for Functional nanostructures (C.F.N.) at the University of Karlsruhe. The mission of the C.F.N. is to carry out research in the following areas: nanophotonics, nanoelectronics, molecular nanostructures and nanostructured materials. The aim of the summer schools is mainly to exchange new ideas and illustrate emerging research methodologies through a series of topical, introductory lectures. This is reflected by both the selection of topics addressed in the present volume, nanoelectronics, as well as the tutorial aspect of the contributions.

  4. [The onset of psychiatric disorders and Wilson's disease].

    Science.gov (United States)

    Benhamla, T; Tirouche, Y D; Abaoub-Germain, A; Theodore, F

    2007-12-01

    Wilson's disease is an infrequent, autosomic recessive pathology, resulting from a loss of function of an adenosine triphosphatase (ATP7B or WDNP), secondarily to a change (more than 60 are described currently), insertion or deletion of the ATP7B gene located on the chromosome 13q14.3-q21.1, which involves a reduction or an absence of the transport of copper in the bile and its accumulation in the body, notably the brain. Wilson's disease is transmitted by an autosomic recessive gene located on the long arm of chromosome 13. The prevalence of the heterozygote is evaluated at 1/90 and the homozygote at 1/30,000. Consanguinity, frequent in the socially geographically isolated populations, increases the prevalence of the disease. The toxic quantities of copper, which accumulate in the liver since early childhood and perhaps before, remain concentrated in the body for years. Hence, cytological and histological modifications can be detected in the biopsies, before the appearance of clinical or biological symptoms of hepatic damage. The accumulation of copper in the liver is due to a defect in the biliary excretion of metal and is accompanied invariably by a deficit in ceruloplasmin; protein synthesized from a transferred ATP7B gene, which causes retention of the copper ions in the liver. The detectable cellular anomalies are of two types: hepatic lesions resulting in acute hepatic insufficiency, acute hepatitis and finally advanced cirrhosis and lesions of the central nervous system responsible for the neurological and psychiatric disorders. In approximately 40-50% of the patients, the first manifestation of Wilson's disease affects the central nervous system. Although copper diffuses in the liver towards the blood and then towards other tissues, it has disastrous consequences only in the brain. It can therefore cause either a progressive neurological disease, or psychiatric disorders. Wilson's disease begins in the form of a hepatic, neurological, or psychiatric

  5. Robert R. Wilson Prize for Achievement in the Physics of Particle Accelerators Lecture: Frontiers of FEL Physics and Technology

    Science.gov (United States)

    Madey, John M. J.

    2012-03-01

    For much of the past 40 years, efforts to advance the capabilities of FELs have focussed on the frontiers of operation at high average power and short wavelengths with impressive and gratifying results. But a number of potentially important additional frontiers remain to be explored. I will briefly describe several of the new areas in which we have worked relating to the exploitation of boundary conditions to enhance oscillator phase coherence and stability, the exploitation of phase coherence to reduce the quantum fluctuations in amplitude of the coherent harmonics, the elucidation of the classical Wheeler-Feynman coherent radiation reaction force in single pass radiation sources, the development of the precision, robust high peak and average power optical elements needed for the reliable operation of these sources and the application of these advances to the development of optimized inverse-Compton x-ray and gamma ray sources.

  6. Higher rank ABJM Wilson loops from matrix models

    Energy Technology Data Exchange (ETDEWEB)

    Cookmeyer, Jonathan [Haverford College,370 Lancaster Avenue, Haverford, PA, 19041 (United States); Liu, James T. [Michigan Center for Theoretical Physics, Department of Physics, University of Michigan,450 Church Street, Ann Arbor, MI, 48109 (United States); Zayas, Leopoldo A. Pando [The Abdus Salam International Centre for Theoretical Physics,Strada Costiera 11, Trieste, 34014 (Italy)

    2016-11-21

    We compute the vacuum expectation values of 1/6 supersymmetric Wilson loops in higher dimensional representations of the gauge group in ABJM theory. We present results for the m-symmetric and m-antisymmetric representations by exploiting standard matrix model techniques. At leading order, in the saddle point approximation, our expressions reproduce holographic results from both D6 and D2 branes corresponding to the antisymmetric and symmetric representations, respectively. We also compute 1/N corrections to the leading saddle point results.

  7. Liver imaging findings of Wilson's disease

    Energy Technology Data Exchange (ETDEWEB)

    Akpinar, Erhan [Hacettepe University, Faculty of Medicine, Department of Radiology, 06100 Ankara (Turkey); Akhan, Okan [Hacettepe University, Faculty of Medicine, Department of Radiology, 06100 Ankara (Turkey)]. E-mail: akhano@tr.net

    2007-01-15

    Wilson's disease is a rare, autosomal-recessive inherited disorder of copper metabolism resulting in accumulation of copper in liver. The form of liver disease varies, depending on the severity of the disease at the time of diagnosis and pathological findings include fatty changes, acute hepatitis, chronic active hepatitis, cirrhosis and occasionally fulminant hepatic necrosis. Liver imaging findings reflect a wide range of physiopathological processes of the disease and also demonstrate the associated findings of cirrhosis in cases with advanced disease.

  8. Syndrome parkinsonien secondaire à une maladie de Wilson chez ...

    African Journals Online (AJOL)

    Nous apportons une observation d'un cas de la maladie de Wilson, révélé par un syndrome parkinsonien. Le diagnostic a reposé sur les troubles neuropsychiques, la présence de l'anneau cornéen de Kayser-Fleischer, et les troubles du métabolisme du cuivre. Le scanner cérébral était normal, et l'IRM cérébrale a montré ...

  9. The Wilson flow and the finite temperature phase transition

    Energy Technology Data Exchange (ETDEWEB)

    Wandelt, M. [Department of Mathematics, School of Mathematics and Natural Sciences,Bergische Universität Wuppertal, Gaußstr. 20, 42119 Wuppertal (Germany); Knechtli, F. [Department of Physics, School of Mathematics and Natural Sciences,Bergische Universität Wuppertal, Gaußstr. 20, 42119 Wuppertal (Germany); Günther, M. [Department of Mathematics, School of Mathematics and Natural Sciences,Bergische Universität Wuppertal, Gaußstr. 20, 42119 Wuppertal (Germany)

    2016-10-12

    We consider the determination of the finite temperature phase transition in the Yang-Mills SU(3) gauge theory. We compute the difference of the spatial and temporal energy density at a physical Wilson flow time. This difference is zero in the confined phase and becomes non zero in the deconfined phase. We locate the phase transition by using a new technique based on an exponential smoothing spline. This method is an alternative to the determination of the phase transition based on the Polyakov loop susceptibility and can also be used with dynamical fermions.

  10. B-physics with $N_f=2$ Wilson fermions

    CERN Document Server

    Bernardoni, F; Bulava, J; Della Morte, M; Fritzsch, P; Garron, N; Gerardin, A; Heitger, J; von Hippel, G; Simma, H; Sommer, R

    2014-01-01

    We report the final results of the ALPHA collaboration for some B-physics observables: $f_B$, $f_{B_s}$ and $m_b$. We employ CLS configurations with 2 flavors of $O(a)$ improved Wilson fermions in the sea and pion masses ranging down to 190 MeV. The b-quark is treated in HQET to order $1/m_b$. The renormalization, the matching and the improvement were performed non-perturbatively, and three lattice spacings reaching $a=0.048$ fm are used in the continuum extrapolation.

  11. Dual conformal transformations of smooth holographic Wilson loops

    Energy Technology Data Exchange (ETDEWEB)

    Dekel, Amit [Nordita, KTH Royal Institute of Technology and Stockholm University, Roslagstullsbacken 23, SE-106 91 Stockholm (Sweden)

    2017-01-19

    We study dual conformal transformations of minimal area surfaces in AdS{sub 5}×S{sup 5} corresponding to holographic smooth Wilson loops and some other related observables. To act with dual conformal transformations we map the string solutions to the dual space by means of T-duality, then we apply a conformal transformation and finally T-dualize back to the original space. The transformation maps between string solutions with different boundary contours. The boundary contours of the minimal surfaces are not mapped back to the AdS boundary, and the regularized area of the surface changes.

  12. BACTERIAL BIOFILMS AND INFECTION (LECTURE

    Directory of Open Access Journals (Sweden)

    Chernjavsky VI

    2013-03-01

    Full Text Available The lecture presents published data on the biofilm – a special from of organization of the microflora of the human body, the role of microbial biofilms in the genesis and development of many common diseases. Different mechanisms of antimicrobial resistance development in biofilm are reviewed in the article

  13. Tata lectures on overlap fermions

    CERN Document Server

    Narayanan, R

    2011-01-01

    Overlap formalism deals with the construction of chiral gauge theories on the lattice. These set of lectures provide a pedagogical introduction to the subject with emphasis on chiral anomalies and gauge field topology. Subtleties associated with the generating functional for gauge theories coupled to chiral fermions are discussed.

  14. Koshiba, Tanaka give Nobel lectures

    CERN Multimedia

    2002-01-01

    Masatoshi Kosiba and Koichi Tanaka presented lectures in English on Sunday, touching on topics ranging from particle physics, to teamwork to commemorate their reception of this year's Nobel Prize for Physics and Chemistry. The two will receive their respective prizes in an awards ceremony scheduled for Tuesday (1 page).

  15. Lectures on algebraic model theory

    CERN Document Server

    Hart, Bradd

    2001-01-01

    In recent years, model theory has had remarkable success in solving important problems as well as in shedding new light on our understanding of them. The three lectures collected here present recent developments in three such areas: Anand Pillay on differential fields, Patrick Speissegger on o-minimality and Matthias Clasen and Matthew Valeriote on tame congruence theory.

  16. The Oskar Klein memorial lectures

    CERN Document Server

    Bergström, Lars

    1991-01-01

    This is an invaluable collection of colloquium-type lectures given by some of the most prominent theoretical physicists of today. In a form accessible to the interested general physicist, it covers topics ranging from the use of field-theoretical methods in different contexts via duality symmetries between various field theories, to the Ads/CFT correspondence and cosmology.

  17. Teaching Idioms: Video or Lecture.

    Science.gov (United States)

    Kenyon, Patricia; Daly, Kimberly

    1991-01-01

    A study evaluated the effectiveness of video instruction in teaching the meanings and uses of idioms to 20 deaf adolescents. Students improved their knowledge and use of idioms more when exposed to the video/discussion approach than to the lecture/discussion approach. (DB)

  18. Applied Fluid Mechanics. Lecture Notes.

    Science.gov (United States)

    Gregg, Newton D.

    This set of lecture notes is used as a supplemental text for the teaching of fluid dynamics, as one component of a thermodynamics course for engineering technologists. The major text for the course covered basic fluids concepts such as pressure, mass flow, and specific weight. The objective of this document was to present additional fluids…

  19. On some 1/4 BPS Wilson-'t Hooft loops

    Science.gov (United States)

    Liu, Chang-Yong; Qin, Li

    2015-10-01

    In this paper, we investigate the 1/4 BPS Wilson-'t Hooft loops in N=4 supersymmetric Yang-Mills theory. We use the bulk D3-brane solutions with both electric and magnetic charges on its world-volume to describe some of 1/4 BPS Wilson-'t Hooft loops. The D3-brane supersymmetric solutions are derived form requiring κ-symmetry. We find the two consistent constraints for Killing spinors and calculate the conserved charges of straight 1/4 BPS Wilson-'t Hooft loops and expectation values of circular 1/4 BPS Wilson-'t Hooft loops separately.

  20. Public Lecture: The Odyssey of Voyager

    CERN Multimedia

    CERN. Geneva

    2015-01-01

    Should you wish to attend to this lecture only (and not the full colloquium), please register here: https://indico.cern.ch/event/387001/registration/ Participants to the full colloquium are automatically registered to the public lectures.

  1. Nature Watch

    Indian Academy of Sciences (India)

    ... Lecture Workshops · Refresher Courses · Symposia · Live Streaming. Home; Journals; Resonance – Journal of Science Education; Volume 3; Issue 5. Nature Watch - Thinking Like a Tahr: When Males and Females go their Separate Ways. M D Madhusudan. Feature Article Volume 3 Issue 5 May 1998 pp 43-47 ...

  2. How We Think and Learn. Lecture Series.

    Science.gov (United States)

    National Learning Center, Washington, DC.

    A lecture series was conducted in 1989 to present information on learning theories by learning theorists. This document contains short texts of the lectures; full texts are available on request. In lecture 1, Robert Chase discusses educational reform and Bonnie Guiton examines educational goals from the perspective of White House policy. In…

  3. The Lecture-Discussion Format Revisited.

    Science.gov (United States)

    Bowman, James S.

    1979-01-01

    A new look at the standard lecture/discussion format for the large introductory college course is offered, along with suggestions to upgrade its quality. Foci for improvement include organization of lecture material, teacher-student interaction, lecture delivery, feedback, discussion group supervision, and course evaluation. (JMD)

  4. Holographic Wilson loops, dielectric interfaces, and topological insulators

    Science.gov (United States)

    Estes, John; O'Bannon, Andy; Tsatis, Efstratios; Wrase, Timm

    2013-05-01

    We use holography to study (3+1)-dimensional N=4 supersymmetric SU(Nc) Yang-Mills theory (SYM) in the large-Nc and large-coupling limits, with a (2+1)-dimensional interface where the Yang-Mills coupling or θ angle changes value, or “jumps.” We consider interfaces that either break all supersymmetry or that preserve half of the N=4 supersymmetry thanks to certain operators localized to the interface. Specifically, we compute the expectation values of a straight timelike Wilson line and of a rectangular Wilson loop in the fundamental representation of SU(Nc). The former gives us the self-energy of a heavy test charge while the latter gives us the potential between heavy test charges. A jumping coupling or θ angle acts much like a dielectric interface in electromagnetism: the self-energy or potential includes the effects of image charges. N=4 SYM with a jumping θ angle may also be interpreted as the low-energy effective description of a fractional topological insulator, as we explain in detail. For nonsupersymmetric interfaces, we find that the self-energy and potential are qualitatively similar to those in electromagnetism, despite the differences between N=4 SYM and electromagnetism. For supersymmetric interfaces, we find dramatic differences from electromagnetism which depend sensitively on the coupling of the test charge to the adjoint scalars of N=4 SYM. In particular, we find one special case where a test charge has a vanishing image charge.

  5. [Advances in the molecular diagnosis of Wilson's disease].

    Science.gov (United States)

    Badenas Orquin, Celia

    2011-01-01

    Wilsońs disease is an autosomal recessive disorder characterized by toxic copper accumulation in the liver and subsequently in the brain and other organs. Clinical diagnosis is based on the detection of low serum ceruloplasmin concentrations, increased urinary copper excretion, Kayser-Fleisher rings in the cornea, and/or high copper levels in hepatic tissue. Diagnosis can be difficult when the typical symptoms of the disease are absent, a situation that can lead to a lack of prophylactic therapy in these patients. Molecular study has improved the diagnosis of this disease, even in doubtful cases. The present article outlines the various techniques applied in the molecular diagnosis of Wilson's disease and the most commonly described mutations. Currently, direct sequencing of the ATP7B gene is the most widely used method to detect mutations. Molecular study and identification of ATP7B gene mutations allow diagnosis of individuals with Wilson's disease and their relatives, as well as the possibility of genetic counselling and prenatal and preimplantation genetic diagnosis. Copyright © 2010 Elsevier España, S.L. All rights reserved.

  6. Comments on higher rank Wilson loops in N = 2∗

    Science.gov (United States)

    Liu, James T.; Zayas, Leopoldo A. Pando; Zhou, Shan

    2018-01-01

    For N = 2∗ theory with U( N ) gauge group we evaluate expectation values of Wilson loops in representations described by a rectangular Young tableau with n rows and k columns. The evaluation reduces to a two-matrix model and we explain, using a combination of numerical and analytical techniques, the general properties of the eigen-value distributions in various regimes of parameters ( N, λ , n, k) where λ is the 't Hooft coupling. In the large N limit we present analytic results for the leading and sub-leading contributions. In the particular cases of only one row or one column we reproduce previously known results for the totally symmetry and totally antisymmetric representations. We also extensively discusss the N = 4 limit of the N = 2∗ theory. While establishing these connections we clarify aspects of various orders of limits and how to relax them; we also find it useful to explicitly address details of the genus expansion. As a result, for the totally symmetric Wilson loop we find new contributions that improve the comparison with the dual holographic computation at one loop order in the appropriate regime.

  7. Intestinal expression of metal transporters in Wilson's disease.

    Science.gov (United States)

    Przybyłkowski, Adam; Gromadzka, Grażyna; Wawer, Adriana; Grygorowicz, Tomasz; Cybulska, Anna; Członkowska, Anna

    2013-12-01

    In Wilson's disease (WND), biallelic ATP7B gene mutation is responsible for pathological copper accumulation in the liver, brain and other organs. It has been proposed that copper transporter 1 (CTR1) and the divalent metal transporter 1 (DMT1) translocate copper across the human intestinal epithelium, while Cu-ATPases: ATP7A and ATP7B serve as copper efflux pumps. In this study, we investigated the expression of CTR1, DMT1 and ATP7A in the intestines of both WND patients and healthy controls to examine whether any adaptive mechanisms to systemic copper overload function in the enterocytes. Duodenal biopsy samples were taken from 108 patients with Wilson's disease and from 90 controls. CTR1, DMT1, ATP7A and ATP7B expression was assessed by polymerase chain reaction and Western blot. Duodenal CTR1 mRNA and protein expression was decreased in WND patients in comparison to control subjects, while ATP7A mRNA and protein production was increased. The variable expression of copper transporters may serve as a defense mechanism against systemic copper overload resulting from functional impairment of ATP7B.

  8. Interest rates in quantum finance: the Wilson expansion and Hamiltonian.

    Science.gov (United States)

    Baaquie, Belal E

    2009-10-01

    Interest rate instruments form a major component of the capital markets. The Libor market model (LMM) is the finance industry standard interest rate model for both Libor and Euribor, which are the most important interest rates. The quantum finance formulation of the Libor market model is given in this paper and leads to a key generalization: all the Libors, for different future times, are imperfectly correlated. A key difference between a forward interest rate model and the LMM lies in the fact that the LMM is calibrated directly from the observed market interest rates. The short distance Wilson expansion [Phys. Rev. 179, 1499 (1969)] of a Gaussian quantum field is shown to provide the generalization of Ito calculus; in particular, the Wilson expansion of the Gaussian quantum field A(t,x) driving the Libors yields a derivation of the Libor drift term that incorporates imperfect correlations of the different Libors. The logarithm of Libor phi(t,x) is defined and provides an efficient and compact representation of the quantum field theory of the Libor market model. The Lagrangian and Feynman path integrals of the Libor market model of interest rates are obtained, as well as a derivation given by its Hamiltonian. The Hamiltonian formulation of the martingale condition provides an exact solution for the nonlinear drift of the Libor market model. The quantum finance formulation of the LMM is shown to reduce to the industry standard Bruce-Gatarek-Musiela-Jamshidian model when the forward interest rates are taken to be exactly correlated.

  9. ACADEMIC TRAINING LECTURES-QUESTIONNAIRE

    CERN Multimedia

    Françoise Benz

    2004-01-01

    ACADEMIC TRAINING Françoise Benz tel. 73127 academic.training@cern.ch SUGGEST AND WIN! Its time to plan the 2004-2005 lecture series. From today until March 19 you have the chance to give your contribution to planning for next year's Academic Training Lecture Series. At the web site: http://cern.ch/Academic.Training/questionnaire you will find questionnaires proposing topics in high energy physics, applied physics and science and society. Answering the questionnaire will help ensure that the selected topics are as close as possible to your interests. In particular requests and comments from students will be much appreciated. To encourage your contribution, the AT Committee will reward one lucky winner with a small prize, a 50 CHF coupon for a book purchase at the CERN bookshop.

  10. Lectures on matrix field theory

    CERN Document Server

    Ydri, Badis

    2017-01-01

    These lecture notes provide a systematic introduction to matrix models of quantum field theories with non-commutative and fuzzy geometries. The book initially focuses on the matrix formulation of non-commutative and fuzzy spaces, followed by a description of the non-perturbative treatment of the corresponding field theories. As an example, the phase structure of non-commutative phi-four theory is treated in great detail, with a separate chapter on the multitrace approach. The last chapter offers a general introduction to non-commutative gauge theories, while two appendices round out the text. Primarily written as a self-study guide for postgraduate students – with the aim of pedagogically introducing them to key analytical and numerical tools, as well as useful physical models in applications – these lecture notes will also benefit experienced researchers by providing a reference guide to the fundamentals of non-commutative field theory with an emphasis on matrix models and fuzzy geometries.

  11. La lecture par le jeu

    OpenAIRE

    Gaudin Roy, Marion; Tièche Christinat, Chantal

    2012-01-01

    En tant que maîtresse de classe développement itinérante, je me suis demandé s’il était possible d’apprendre la lecture en jouant. Puis d’autre questions ont suivi : qu’est-ce que la lecture ? Qu’est-ce que le jeu ? Le jeu est perçu comme un loisir voire comme une activité oisive. Il est donc en opposition à l’apprentissage qui est perçu comme difficile et demandant des efforts. Comment se situer en tant qu’enseignante ? A travers ce mémoire, j’ai pu répondre à ces interrogations. Pour...

  12. The Cultural Origins and Play Philosophy of Playworkers: An Interview with Penny Wilson

    Science.gov (United States)

    American Journal of Play, 2009

    2009-01-01

    Penny Wilson is a playworker--one of a group of professionals who facilitate children's play in adventure playgrounds, parks, and other settings, principally in the United Kingdom. Wilson grew up in the Southeast of England and spent much of her childhood playing on the coast near her family home. She studied illustration in art school, settled in…

  13. War, Medicine, and Cultural Diplomacy in the Americas: Frank Wilson and Brazilian cardiology.

    Science.gov (United States)

    Kropf, Simone P; Howell, Joel D

    2017-10-01

    American cultural diplomacy played a key role in the institutionalization of Brazilian cardiology. In 1942, Frank Wilson, an internationally recognized pioneer in electrocardiography, made an extended wartime visit to Rio de Janeiro and São Paulo. The visit was sponsored by the United States Department of State as part of Roosevelt's Good Neighbor Policy and brought Wilson together with a group of physicians who would establish the specialty of cardiology in Brazil. This US cultural and diplomatic initiative strengthened an academic network that was already evolving and would eventually prove to be of benefit to both sides. Latin American physicians began in the 1920s to visit Wilson's laboratory at the University of Michigan, where they established the relationships on which Wilson would build. While affiliation with the "Wilson school" advanced the cause of Brazilian cardiologists who sought to establish themselves as specialists, cooperation with Latin American physicians benefitted Wilson in his pursuit of wider recognition for his innovations in the use of electrocardiography (ECG). Wilson's identity as a scientific ambassador to Latin America helped in legitimating his approach to the clinical application of the ECG. A close examination of Wilson's relationship to Brazilian cardiology demonstrates the role played by science and medicine as a part of wartime cultural diplomacy, as well as the dynamics of the transnational circulation of scientific knowledge and practices. © The Author 2017. Published by Oxford University Press. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  14. "Mens Sana in Corpore Sano": Human Values in Thomas Wilson's "The Arte of Rhetorique."

    Science.gov (United States)

    Luehring, Janet

    In 1553 the work that is touted as the first complete book written in English on rhetoric was published, Thomas Wilson's "Arte of Rhetorique." It became so popular it enjoyed eight printings within its century. Wilson was not a person to translate and read just for knowledge; he believed that knowledge should be imparted to the general…

  15. The Modern First Lady and Public Policy: From Edith Wilson through Hillary Rodham Clinton.

    Science.gov (United States)

    Black, Allida M.

    2001-01-01

    Discusses the role in and influence on public policy of twentieth century First Ladies including Edith Roosevelt, Helen Taft, Ellen Wilson, Edith Wilson, Florence Harding, Lou Henry Hoover, Eleanor Roosevelt, Jacqueline Kennedy, Lady Bird Johnson, Rosalynn Carter, Nancy Reagan, Barbara Bush, and Hillary Rodham Clinton. (CMK)

  16. Long-Term Exclusive Zinc Monotherapy in Symptomatic Wilson Disease : Experience in 17 Patients

    NARCIS (Netherlands)

    Linn, Francisca H. H.; Houwen, Roderick H. J.; van Hattum, Jan; van der Kleij, Stefan; van Erpecum, Karel J.

    2009-01-01

    Exclusive monotherapy with zinc in symptomatic Wilson disease is controversial. Seventeen symptomatic patients with Wilson disease were treated with zinc only. The mean age at diagnosis and start of treatment was 18 years (range 13-26) with approximately half presenting as adolescents. Presentation

  17. Lecture Notes in Lie Groups

    OpenAIRE

    Ivancevic, Vladimir G.; Ivancevic, Tijana T.

    2011-01-01

    These lecture notes in Lie Groups are designed for a 1--semester third year or graduate course in mathematics, physics, engineering, chemistry or biology. This landmark theory of the 20th Century mathematics and physics gives a rigorous foundation to modern dynamics, as well as field and gauge theories in physics, engineering and biomechanics. We give both physical and medical examples of Lie groups. The only necessary background for comprehensive reading of these notes are advanced calculus ...

  18. Lectures in Complex Systems (1991)

    Science.gov (United States)

    1992-08-05

    Grossberg, S., and J. Pepe. "Schizophrenia: Possible Dependence of Associ- ational Span, Bowing, and Primacy vs. Recency on Spiking Threshold." Be...Parameters, Broken Symmetry, and Topology James P. Sethna 243 Meissner Effects and Constraints James P. Sethna 267 1991 Lectures in Complex Systems, SR...two eyes segregate from each other to form layers or columns? The first clues came from the pioneering studies of Hubel and Wiesel on the effects of

  19. Mapping the Universe: The 2010 Russell Lecture

    Science.gov (United States)

    Geller, Margaret J.; Diaferio, Antonaldo; Kurtz, Michael J.

    2011-10-01

    Redshift surveys are a powerful tool of modern cosmology. We discuss two aspects of their power to map the distribution of mass and light in the universe: (1) measuring the mass distribution extending into the infall regions of rich clusters and (2) applying deep redshift surveys to the selection of clusters of galaxies and to the identification of very large structures (Great Walls). We preview the HectoMAP project, a redshift survey with median redshift z = 0.34 covering 50 deg2 to r = 21. We emphasize the importance and power of spectroscopy for exploring and understanding the nature and evolution of structure in the universe. This paper preserves the substance and style of Margaret Geller's 2010 Russell Lecture presented at the May 2011 Boston AAS Meeting.

  20. Circular Wilson loops in defect conformal field theory

    Science.gov (United States)

    Aguilera-Damia, Jeremías; Correa, Diego H.; Giraldo-Rivera, Victor I.

    2017-03-01

    We study a D3-D5 system dual to a conformal field theory with a codimension-one defect that separates regions where the ranks of the gauge groups differ by k. With the help of this additional parameter, as observed by Nagasaki, Tanida and Yamaguchi, one can define a double scaling limit in which the quantum corrections are organized in powers of λ/k 2, which should allow to extrapolate results between weak and strong coupling regimes. In particular we consider a radius R circular Wilson loop placed at a distance L, whose internal space orientation is given by an angle χ. We compute its vacuum expectation value and show that, in the double scaling limit and for small χ and small L/R, weak coupling results can be extrapolated to the strong coupling limit.

  1. The Mount Wilson Optical Shop during the Second World War

    Science.gov (United States)

    Abrahams, P.

    2004-12-01

    During the Second World War, the Optical Shop of Mount Wilson Observatory, located in Pasadena, engaged in a variety of exacting and pioneering ventures in optical design and fabrication. Roof prisms for military optics were produced on a large scale, leading to the production of an instruction manual, for guidance in other workshops. Triple mirrors, or autocollimating corner cubes, were another precision part made in large numbers. Aerial photography was extensively developed. Test procedures for measuring resolution of lenses were researched. Various camera shutters and film sweep mechanisms were devised. The most significant work concerned Schmidt cameras, for possible use in night-time aerial photography. Variations included a solid Schmidt, and the Schmidt Cassegrain, which was fabricated for the first time at MWO. Key figures include Don Hendrix, Roger Hayward, Aden Meinel, and Walter Adams.

  2. Holomorphic variables in magnetized brane models with continuous Wilson lines

    CERN Document Server

    Camara, Pablo G; Dudas, Emilian

    2010-01-01

    We analyze the action of the target-space modular group in toroidal type IIB orientifold compactifications with magnetized D-branes and continuous Wilson lines. The transformation of matter fields agree with that of twisted fields in heterotic compactifications, constituting a check of type I/heterotic duality. We identify the holomorphic N = 1 variables for these compactifications. Matter fields and closed string moduli are both redefined by open string moduli. The redefinition of matter fields can be read directly from the perturbative Yukawa couplings, whereas closed string moduli redefinitions are obtained from D-brane instanton superpotential couplings. The resulting expressions reproduce and generalize, in the presence of internal magnetic fields, previous results in the literature.

  3. Clinical presentation and mutations in Danish patients with Wilson disease

    DEFF Research Database (Denmark)

    Møller, Lisbeth Birk; Horn, Nina; Jeppesen, Tina Dysgaard

    2011-01-01

    consistently indicative of WND, with the exception of the 24-h urine-Cu test, which is always outside the normal range. Mutations were identified in 100% of the screened ATP7B alleles (70 unrelated), including five novel mutations: p.1021K; p.G1158V; p.L1304F; IVS20-2A>G; Ex5_6del. In all, 70% of mutations...... were found in exons 8, 14, 17, 18, and 20. The most frequent mutation, p.H1069Q, comprised 18%. We propose a new and simple model that correlates genotype and age of onset. By assuming that the milder of two mutations is 'functionally dominant' and determines the age of onset, we classified 25....../27 mutations as either severe (age of onset 20 years), and correctly predicted the age of onset in 37/39 patients. This method should be tested in other Wilson populations....

  4. Progressive hip joint subluxation in Saul-Wilson syndrome.

    Science.gov (United States)

    Chinen, Yasutsugu; Kaneshi, Takuya; Kamiya, Takeshi; Hata, Kenichiro; Nishimura, Gen; Kaname, Tadashi

    2015-11-01

    Saul-Wilson syndrome (SWS) is a rare congenital skeletal syndrome characterized by postnatal onset of short stature, relative microcephaly, frontal bossing, prominent eyes with shallow orbits, midface hypoplasia, cataract, and generalized skeletal changes, including spondylar dysplasia, overtubulation of the long bones with metaphyseal flaring and megaepiphyses, coxa valga, elbow deformity, and brachydactyly. We describe a boy with the overall clinical and radiological features fitting the characteristics of SWS, although cataract, elbow deformity, and overt brachydactyly were not seen. He presented with painful hip joint due to hip subluxation in late childhood, which exacerbated with age and ultimately, required surgical intervention. Awareness of this orthopedic complication in SWS is essential in the management of patients with SWS. © 2015 Wiley Periodicals, Inc.

  5. Gravity duals of half-BPS Wilson loops

    Energy Technology Data Exchange (ETDEWEB)

    D' Hoker, Eric; Estes, John; Gutperle, Michael [Department of Physics and Astronomy, University of California, Los Angeles, CA 90095 (United States)

    2007-06-15

    We explicitly construct the fully back-reacted half-BPS solutions in Type IIB supergravity which are dual to Wilson loops with 16 supersymmetries in N = 4 super Yang-Mills. In a first part, we use the methods of a companion paper to derive the exact general solution of the half-BPS equations on the space AdS{sub 2} x S{sup 2} x S{sup 4} x {sigma}, with isometry group SO(2, 1) x SO(3) x SO(5) in terms of two locally harmonic functions on a Riemann surface {sigma} with boundary. These solutions, generally, have varying dilaton and axion, and non-vanishing 3-form fluxes. In a second part, we impose regularity and topology conditions. These non-singular solutions may be parametrized by a genus g {>=} 0 hyperelliptic surface {sigma}, all of whose branch points lie on the real line. Each genus g solution has only a single asymptotic AdS{sub 5} x S{sup 5} region, but exhibits g homology 3-spheres, and an extra g homology 5-spheres, carrying respectively RR 3-form and RR 5-form charges. For genus 0, we recover AdS{sub 5} x S{sup 5} with 3 free parameters, while for genus g {>=} 1, the solution has 2g+5 free parameters. The genus 1 case is studied in detail. Numerical analysis is used to show that the solutions are regular throughout the g = 1 parameter space. Collapse of a branch cut on {sigma} subtending either a homology 3-sphere or a homology 5-sphere is non-singular and yields the genus g-1 solution. This behavior is precisely expected of a proper dual to a Wilson loop in gauge theory.

  6. Results of treatment of Wilson's disease--own observations.

    Science.gov (United States)

    Jabłońska-Kaszewska, Irena; Drobińska-Jurowiecka, Anna; Dabrowska, Ewa; Trocha, Hanna

    2003-08-01

    Causative treatment of genetically determined Wilson's disease (WD) has been impossible so far, although gene therapy could be real in the future. Nowadays the principle of treatment is the elimination of the excess of easily mobilized copper, bound by chelating agents, the most important of which is d-penicillamine, through the kidneys. Blocking of the intestinal absorption of copper by administration of zinc preparations, which additionally induce hepatic metallothionein synthesis, is also possible. The aim of our study was to present own observations and results of treatment of Wilson's disease. During the last 16 years, we have observed 33 patients aged 13-60 (mean age 27 years) with various forms of WD. The studied group consisted of 11 females and 21 males, admitted to hospital or seen at the Specialistic Outpatient Department of Hepatology with various diagnoses. In addition to standard laboratory tests, the levels of ceruloplasmin, serum and urine copper, as well as the activity of some hepatic enzymes, proteins and HBV/HCV infection markers were determined. The patients were also examined by a neurologist and an ophthalmologist, with psychiatric consultation if necessary. Taking into account the overall clinical presentation, the patients were divided into the following groups according to the form of the disease: fulminant, acute, hepatic, hepatic with neurological and psychiatric symptoms, neuropsychiatric, asymptomatic. All the patients were initially treated with d-penicillamine. In most of them, no side effects were observed. The treatment was continued according to the levels of copper excreted with urine (for 10 years at the longest). After obtaining clinical improvement with reduced amount of copper excreted with 24-h urine, we tapered d-penicillamine doses or even discontinued the drug, introducing zinc preparations. In asymptomatic carriers, zinc preparations were used throughout the period of treatment. Early institution of chelation treatment

  7. Currently Clinical Views on Genetics of Wilson's Disease.

    Science.gov (United States)

    Chen, Chen; Shen, Bo; Xiao, Jia-Jia; Wu, Rong; Duff Canning, Sarah Jane; Wang, Xiao-Ping

    2015-07-05

    The objective of this study was to review the research on clinical genetics of Wilson's disease (WD). We searched documents from PubMed and Wanfang databases both in English and Chinese up to 2014 using the keywords WD in combination with genetic, ATP7B gene, gene mutation, genotype, phenotype. Publications about the ATP7B gene and protein function associated with clinical features were selected. Wilson's disease, also named hepatolenticular degeneration, is an autosomal recessive genetic disorder characterized by abnormal copper metabolism caused by mutations to the copper-transporting gene ATP7B. Decreased biliary copper excretion and reduced incorporation of copper into apoceruloplasmin caused by defunctionalization of ATP7B protein lead to accumulation of copper in many tissues and organs, including liver, brain, and cornea, finally resulting in liver disease and extrapyramidal symptoms. It is the most common genetic neurological disorder in the onset of adolescents, second to muscular dystrophy in China. Early diagnosis and medical therapy are of great significance for improving the prognosis of WD patients. However, diagnosis of this disease is usually difficult because of its complicated phenotypes. In the last 10 years, an increasing number of clinical studies have used molecular genetics techniques. Improved diagnosis and prediction of the progression of this disease at the molecular level will aid in the development of more individualized and effective interventions, which is a key to transition from molecular genetic research to the clinical study. Clinical genetics studies are necessary to understand the mechanism underlying WD at the molecular level from the genotype to the phenotype. Clinical genetics research benefits newly emerging medical treatments including stem cell transplantation and gene therapy for WD patients.

  8. natural

    Directory of Open Access Journals (Sweden)

    Elías Gómez Macías

    2006-01-01

    Full Text Available Partiendo de óxido de magnesio comercial se preparó una suspensión acuosa, la cual se secó y calcinó para conferirle estabilidad térmica. El material, tanto fresco como usado, se caracterizó mediante DRX, área superficial BET y SEM-EPMA. El catalizador mostró una matriz de MgO tipo periclasa con CaO en la superficie. Las pruebas de actividad catalítica se efectuaron en lecho fijo empacado con partículas obtenidas mediante prensado, trituración y clasificación del material. El flujo de reactivos consistió en mezclas gas natural-aire por debajo del límite inferior de inflamabilidad. Para diferentes flujos y temperaturas de entrada de la mezcla reactiva, se midieron las concentraciones de CH4, CO2 y CO en los gases de combustión con un analizador de gases tipo infrarrojo no dispersivo (NDIR. Para alcanzar conversión total de metano se requirió aumentar la temperatura de entrada al lecho a medida que se incrementó el flujo de gases reaccionantes. Los resultados obtenidos permiten desarrollar un sistema de combustión catalítica de bajo costo con un material térmicamente estable, que promueva la alta eficiencia en la combustión de gas natural y elimine los problemas de estabilidad, seguridad y de impacto ambiental negativo inherentes a los procesos de combustión térmica convencional.

  9. Lectures

    OpenAIRE

    Ceccaldi, Sylviane; Leménager, Nathalie; Thévenot, Magali

    2010-01-01

    Accès à l’emploi et insertion L'insertion professionnelle des travailleurs handicapés. En France, de 1987 à nos jours Blanc Alain (Dir.)Grenoble, PUG, 2009, 311 p.Collection « Handicap, Vieillissement, Société » Élaboré dans l'entre-deux-guerres, le dispositif d'insertion professionnelle dédié aux travailleurs handicapés a peu évolué : il se caractérise toujours par le triple processus de définition des bénéficiaires, de mise en œuvre d'actions de médiations leur permettant d'accéder à l'empl...

  10. Détermination expérimentale des paramètres de Wilson Experimental Dertermination of Wilson Parameters

    Directory of Open Access Journals (Sweden)

    Monfort J.-P.

    2006-11-01

    Full Text Available La volabilité relative ait; =(yilxil(Y;lxi des constituants d'un mélange binaire a été mesurée à partir d'un nouveau dispositif expérimental, on reporte les données d'équilibre liquide-vapeur obtenues à 45'C de plusieurs binaires : toluène-acétoni-trile, benzène-acétonitrile et benzène-n-heptane. En ajustant à l'équation de Wilson les données expérimentales de «i/; de ces constituants ainsi que des volatilités relatives des constituants des mélanges d'hydrocarbures-alcools, obtenues dans un précédent travail, on calcule les paramètres énergétiques. La prédiction des points de bulle de mélanges binaires et ternaires obtenue à partir de ces paramètres est satisfaisante. La méthode expérimentale ainsi proposée convient particulièrement pour la sélection des solvant extractifs utilisés dans la distillation extractive. From a new expérimental method, relative volatilities aiti = (yilxil(yilxi for a binary mixture are obtained; vapor-liquid equilibrium data are presented for several systems, i.e. toluene-acétonitrile, benzene-acétonitrile and benzene-n-heptane at 45°C. The two adjustable energyparameters of thé Wilson équation, are obtained by adopting thé «,/j data for these binary mixtures and for alcohol-hydrocarbon mixtures previously studied. Theresults obtained in predicting bubble-pressure data for binary and ternary mixtures are consistent with experimental data.

  11. Lecture Notes on Multigrid Methods

    Energy Technology Data Exchange (ETDEWEB)

    Vassilevski, P S

    2010-06-28

    The Lecture Notes are primarily based on a sequence of lectures given by the author while been a Fulbright scholar at 'St. Kliment Ohridski' University of Sofia, Sofia, Bulgaria during the winter semester of 2009-2010 academic year. The notes are somewhat expanded version of the actual one semester class he taught there. The material covered is slightly modified and adapted version of similar topics covered in the author's monograph 'Multilevel Block-Factorization Preconditioners' published in 2008 by Springer. The author tried to keep the notes as self-contained as possible. That is why the lecture notes begin with some basic introductory matrix-vector linear algebra, numerical PDEs (finite element) facts emphasizing the relations between functions in finite dimensional spaces and their coefficient vectors and respective norms. Then, some additional facts on the implementation of finite elements based on relation tables using the popular compressed sparse row (CSR) format are given. Also, typical condition number estimates of stiffness and mass matrices, the global matrix assembly from local element matrices are given as well. Finally, some basic introductory facts about stationary iterative methods, such as Gauss-Seidel and its symmetrized version are presented. The introductory material ends up with the smoothing property of the classical iterative methods and the main definition of two-grid iterative methods. From here on, the second part of the notes begins which deals with the various aspects of the principal TG and the numerous versions of the MG cycles. At the end, in part III, we briefly introduce algebraic versions of MG referred to as AMG, focusing on classes of AMG specialized for finite element matrices.

  12. What is Gravitational Lensing? (LBNL Summer Lecture Series)

    Energy Technology Data Exchange (ETDEWEB)

    Leauthaud, Alexie; Nakajima, Reiko [Berkeley Center for Cosmological Physics

    2009-07-28

    Summer Lecture Series 2009: Gravitational lensing is explained by Einstein's general theory of relativity: galaxies and clusters of galaxies, which are very massive objects, act on spacetime by causing it to become curved. Alexie Leauthaud and Reiko Nakajima, astrophysicists with the Berkeley Center for Cosmological Physics, will discuss how scientists use gravitational lensing to investigate the nature of dark energy and dark matter in the universe.

  13. 2013-2016 Lecture Series

    OpenAIRE

    Scheid, John

    2015-01-01

    The launch in May 2014 of the lecture series delivered by Visiting Professor Jean-Louis Cohen from New York University, opened a new chapter in the history of teaching at the Collège de France, namely that of the Pluri-Annual Visiting Professorships. The new system increases the Collège de France’s freedom of action: it can now invite professors and ask them to teach for relatively long periods of time, even if they choose not to give up the permanent position they hold in another institution...

  14. Lectures on quantum field theory

    CERN Document Server

    Das, Ashok

    2008-01-01

    This book consists of the lectures for a two-semester course on quantum field theory, and as such is presented in a quite informal and personal manner. The course starts with relativistic one-particle systems, and develops the basics of quantum field theory with an analysis of the representations of the Poincaré group. Canonical quantization is carried out for scalar, fermion, Abelian and non-Abelian gauge theories. Covariant quantization of gauge theories is also carried out with a detailed description of the BRST symmetry. The Higgs phenomenon and the standard model of electroweak interactio

  15. Nobel Lecture: Topological quantum matter*

    Science.gov (United States)

    Haldane, F. Duncan M.

    2017-10-01

    Nobel Lecture, presented December 8, 2016, Aula Magna, Stockholm University. I will describe the history and background of three discoveries cited in this Nobel Prize: The "TKNN" topological formula for the integer quantum Hall effect found by David Thouless and collaborators, the Chern insulator or quantum anomalous Hall effect, and its role in the later discovery of time-reversal-invariant topological insulators, and the unexpected topological spin-liquid state of the spin-1 quantum antiferromagnetic chain, which provided an initial example of topological quantum matter. I will summarize how these early beginnings have led to the exciting, and currently extremely active, field of "topological matter."

  16. Mechanics lectures on theoretical physics

    CERN Document Server

    Sommerfeld, Arnold Johannes Wilhelm

    1952-01-01

    Mechanics: Lectures on Theoretical Physics, Volume I covers a general course on theoretical physics. The book discusses the mechanics of a particle; the mechanics of systems; the principle of virtual work; and d'alembert's principle. The text also describes oscillation problems; the kinematics, statics, and dynamics of a rigid body; the theory of relative motion; and the integral variational principles of mechanics. Lagrange's equations for generalized coordinates and the theory of Hamilton are also considered. Physicists, mathematicians, and students taking Physics courses will find the book

  17. Non-dipolar Wilson links for transverse-momentum-dependent wave functions

    Energy Technology Data Exchange (ETDEWEB)

    Li, Hsiang-nan [Institute of Physics, Academia Sinica,Taipei, Taiwan 115 (China); Department of Physics, National Cheng-Kung University,Tainan, Taiwan 701 (China); Department of Physics, National Tsing-Hua University,Hsinchu, Taiwan 300 (China); Wang, Yu-Ming [Institut für Theoretische Teilchenphysik und Kosmologie RWTH Aachen,D-52056 Aachen (Germany); Physik Department T31, James-Franck-Straße, Technische Universität München,D-85748 Garching (Germany)

    2015-06-03

    We propose a new definition of a transverse-momentum-dependent (TMD) wave function with simpler soft subtraction for k{sub T} factorization of hard exclusive processes. The un-subtracted wave function involves two pieces of non-light-like Wilson links oriented in different directions, so that the rapidity singularity appearing in usual k{sub T} factorization is regularized, and the pinched singularity from Wilson-link self-energy corrections is alleviated to a logarithmic one. In particular no soft function is needed, when the two pieces of Wilson links are orthogonal to each other. We show explicitly at one-loop level that the simpler definition with the non-dipolar Wilson links exhibits the same infrared behavior as the one with the dipolar Wilson links and complicated soft subtraction. It is pointed out that both definitions reduce to the naive TMD wave function as the non-light-like Wilson links approach to the light cone. Their equivalence is then extended to all orders by considering the evolution in the Wilson-link rapidity.

  18. Wilson's disease presenting as rapid eye movement sleep behavior disorder: a possible window to early treatment.

    Science.gov (United States)

    Tribl, Gotthard G; Bor-Seng-Shu, Edson; Trindade, Mateus C; Lucato, Leandro T; Teixeira, Manoel J; Barbosa, Egberto R

    2014-09-01

    To describe characteristics of REM sleep behavior disorder in Wilson's disease. Questionnaire-based interviews (patients and relatives), neurological examinations, two-week prospective dream-diary, video-polysomnography, transcranial sonography, MRI. Four Wilson's disease cases with REM sleep behavior disorder were described; three had REM sleep behavior disorder as initial symptom. All showed mesencephalic tegmental/tectal sonographic hyperechogenicities and two presented ponto-mesencephalic tegmental MRI hyperintensities. This first description of REM sleep behavior disorder in Wilson's disease in literature documents REM sleep behavior disorder as a possible presenting symptom of Wilson's disease and adds further evidence to the parallelism of Parkinson's disease and Wilson's disease in phenotype and brainstem topography, which ought to be further studied. REM sleep behavior disorder has prognostic relevance for neurodegeneration in α-synucleinopathies. In Wilson's disease, usefulness of early diagnosis and treatment are already well established. REM sleep behavior disorder in Wilson's disease offers a possible theoretical model for potential early treatment in this extrapyramidal and brainstem paradigm syndrome, previewing the possibility of neuroprotective treatment for REM sleep behavior disorder in "pre-clinical" Parkinson's disease.

  19. Prevalence of ATP7B Gene Mutations in Iranian Patients With Wilson Disease

    OpenAIRE

    Zali, Narges; Mohebbi, Seyed Reza; Esteghamat, Sahar; Chiani, Mohsen; Haghighi, Mahdi Montazer; Hosseini-Asl, Seyed Mohammad-Kazem; Derakhshan, Faramarz; Mohammad-Alizadeh, Amir-Houshang; Malek-Hosseini, Seyed-Ali; Zali, Mohammad Reza

    2011-01-01

    Background Wilson disease (WD) is an autosomal recessive disorder. The WD gene, ATP7B, encodes a copper-transporting ATPase involved in the transport of copper into the plasma protein ceruloplasmin and in excretion of copper from the liver. ATP7B mutations cause copper to accumulate in the liver and brain. Objectives We examined the ATP7B mutation spectrum in Wilson disease patients in Iran. Patients and Methods Genomic DNA was extracted from patients with Wilson disease. The entire coding re...

  20. Web Lectures - ATLAS Overview Week

    CERN Multimedia

    Tushar Bhatnagar; Jeremy Herr; Mitch McLachlan; Homer A. Neal

    2007-01-01

    ATLAS Web Archives Web Archives of the ATLAS Overview Week in Glasgow are now available from the University of Michigan portal here. Archives of ATLAS Plenary Sessions, Workshops, Meetings, and Tutorials recorded over the past two years are available via the University of Michigan Lecture Portal. Other recent additions include the ROOT Workshop held at CERN on March 26-27, the Physics Analysis Tools Workshop held in Bergen, Norway on April 23-27, and the CTEQ Workshop: "Physics at the LHC: Early Challenges" held at Michigan State University on May 14-15. Viewing requires a standard Web browser with RealPlayer plug-in (included in most browsers automatically) and works on any major platform. Lectures can be viewed directly over the Web or downloaded locally. In addition, you will find access to a variety of general tutorials and events via the portal. Feedback & Suggestions Welcome Suggestions for events or tutorials to record in 2007, as well as feedback on existing archives, is always welcome...

  1. Lectures on Geophysical Fluid Dynamics

    Science.gov (United States)

    Samelson, Roger M.

    The fluid kaleidoscope of the Earth's ocean and atmosphere churns and sparkles with jets, gyres, eddies, waves, streams, and cyclones. These vast circulations, essential elements of the physical environment that support human life, are given a special character by the Earth's rotation and by their confinement to a shallow surficial layer, thin relative to the solid Earth in roughly the same proportion as an apple skin is to an apple. Geophysical fluid dynamics exploits this special character to develop a unified theoretical approach to the physics of the ocean and atmosphere.With Lectures on Geophysical Fluid Dynamics, Rick Salmon has added an insightful and provocative volume to the handful of authoritative texts currently available on the subject. The book is intended for first-year graduate students, but advanced students and researchers also will find it useful. It is divided into seven chapters, the first four of these adapted from course lectures. The book is well written and presents a fresh and stimulating perspective that complements existing texts. It would serve equally well either as the main text for a core graduate curriculum or as a supplementary resource for students and teachers seeking new approaches to both classical and contemporary problems. A lively set of footnotes contains many references to very recent work. The printing is attractive, the binding is of high quality, and typographical errors are few.

  2. Lectures on the Topological Vertex

    CERN Document Server

    Mariño, M

    2008-01-01

    In this lectures, I will summarize the approach to Gromov–Witten invariants on toric Calabi–Yau threefolds based on large N dualities. Since the large N duality/topological vertex approach computes Gromov–Witten invariants in terms of Chern–Simons knot and link invariants, Sect. 2 is devoted to a review of these. Section 3 reviews topological strings and Gromov–Witten invariants, and gives some information about the open string case. Section 4 introduces the class of geometries we will deal with, namely toric (noncompact) Calabi–Yau manifolds, and we present a useful graphical way to represent these manifolds which constitutes the geometric core of the theory of the topological vertex. Finally, in Sect. 5, we define the vertex and present some explicit formulae for it and some simple applications. A brief Appendix contains useful information about symmetric polynomials. It has not been possible to present all the relevant background and physical derivations in this set of lectures. However, these...

  3. Do Pictures "Tell" a Thousand Words in Lectures? How Lecturers Vocalise Photographs in Their Presentations

    Science.gov (United States)

    Hallewell, Madeline J.; Lackovic, Natasa

    2017-01-01

    This article explores how 145 photographs collected from 20 PowerPoint lectures in undergraduate psychology at 16 UK universities were integrated with lecturers' speech. Little is currently known about how lecturers refer to the distinct types of photographs included in their presentations. Findings show that only 48 photographs (33%) included in…

  4. The Use of Lecture Recordings in Higher Education: A Review of Institutional, Student, and Lecturer Issues

    Science.gov (United States)

    O'Callaghan, Frances V.; Neumann, David L.; Jones, Liz; Creed, Peter A.

    2017-01-01

    Web-based lecture technologies are being used increasingly in higher education. One widely-used method is the recording of lectures delivered during face-to-face teaching of on-campus courses. The recordings are subsequently made available to students on-line and have been variously referred to as lecture capture, video podcasts, and Lectopia. We…

  5. Improving Lecture Quality through Training in Public Speaking

    Science.gov (United States)

    Mowbray, Robert; Perry, Laura B.

    2015-01-01

    Lecturing is a common instructional format but poor lecturing skills can detract from students' learning experiences and outcomes. As lecturing is essentially a form of public communication, training in public speaking may improve lecture quality. Twelve university lecturers in Malaysia participated in a six-week public speaking skills training…

  6. Peace through Institutions: Woodrow Wilson and the Paris Peace Conference

    Directory of Open Access Journals (Sweden)

    Burak Küntay

    2014-12-01

    Full Text Available As we approach the centennial of World War I, it is fitting to undertake a retrospective, academic review of the institutions devised in the war’s aftermath. The efforts to build and sustain a global order ensuring peace and cooperation in the international community - which ultimately failed with the beginning of a Second World War—constitute telling and timely lessons for world politics today. This paper looks critically at America’s role in World War I, diplomatic talks preceding the signature of the treaty of Versailles, and domestic and international reactions to President Woodrow Wilson’s signature idealism.The paper begins with a historical overview of how World War I began in Europe in an effort to contextualize the entrance of the United States in 1917, two and a half years after the war began. Since Woodrow Wilson originally promoted American neutrality, and U.S. public opinion had mostly favored isolationism until World War I, Wilson’s presidency represents a historic shift in American foreign policy to interventionism and eventually, its post-Cold War “global policeman” status. Assessing the main actors of WWI and America’s role in it serves to frame Woodrow Wilson’s asymmetrical reception within his own country. In the U.S., Wilson’s foreign affairs record is characterized by his intervention in Mexico, his original attempt to remain uninvolved in Europe’s war, and his failed attempt to keep peace after the war. Wilson garnered domestic support for U.S. entrance with his call to “make the world safe for democracy.” Using such overt idealistic rhetoric in the foreign policymaking decision process was novel at the time, but sounds all too familiar today. Post-WWI, Wilson’s fight with Congress and the U.S. not entering into the League of Nations resembles rifts between U.S. administrations and their Congresses in recent times, and it arguably indirectly contributed to the occurrence of the World War II. As U

  7. Elevated copper impairs hepatic nuclear receptor function in Wilson's disease.

    Science.gov (United States)

    Wooton-Kee, Clavia Ruth; Jain, Ajay K; Wagner, Martin; Grusak, Michael A; Finegold, Milton J; Lutsenko, Svetlana; Moore, David D

    2015-09-01

    Wilson's disease (WD) is an autosomal recessive disorder that results in accumulation of copper in the liver as a consequence of mutations in the gene encoding the copper-transporting P-type ATPase (ATP7B). WD is a chronic liver disorder, and individuals with the disease present with a variety of complications, including steatosis, cholestasis, cirrhosis, and liver failure. Similar to patients with WD, Atp7b⁻/⁻ mice have markedly elevated levels of hepatic copper and liver pathology. Previous studies have demonstrated that replacement of zinc in the DNA-binding domain of the estrogen receptor (ER) with copper disrupts specific binding to DNA response elements. Here, we found decreased binding of the nuclear receptors FXR, RXR, HNF4α, and LRH-1 to promoter response elements and decreased mRNA expression of nuclear receptor target genes in Atp7b⁻/⁻ mice, as well as in adult and pediatric WD patients. Excessive hepatic copper has been described in progressive familial cholestasis (PFIC), and we found that similar to individuals with WD, patients with PFIC2 or PFIC3 who have clinically elevated hepatic copper levels exhibit impaired nuclear receptor activity. Together, these data demonstrate that copper-mediated nuclear receptor dysfunction disrupts liver function in WD and potentially in other disorders associated with increased hepatic copper levels.

  8. Update on the clinical management of Wilson's disease.

    Science.gov (United States)

    Hedera, Peter

    2017-01-01

    Wilson's disease (WD), albeit relatively rare, is an important genetic metabolic disease because of highly effective therapies that can be lifesaving. It is a great imitator and requires a high index of suspicion for correct and timely diagnosis. Neurologic, psychiatric and hepatologic problems in WD are very nonspecific, and we discuss the most common clinical phenotypes. The diagnosis remains laboratory based, and here we review the most important challenges and pitfalls in laboratory evaluation of WD, including the emerging role of genetic testing in WD diagnosis. WD is a monogenic disorder but has very high allelic heterogeneity with >500 disease-causing mutations identified, and new insights into phenotype-genotype correlations are also reviewed. The gold standard of therapy is chelation of excessive copper, but many unmet needs exist because of possible clinical deterioration in treated patients and potential adverse effects associated with currently available chelating medications. We also review the most promising novel therapeutic approaches, including chelators targeting specific cell types, cell transplantation and gene therapy.

  9. Outcomes of Hirschsprung's disease associated with Mowat-Wilson syndrome.

    Science.gov (United States)

    Bonnard, Arnaud; Zeidan, Smart; Degas, Vanessa; Viala, Jérome; Baumann, Clarisse; Berrebi, Dominique; Perrusson, Odile; El Ghoneimi, Alaa

    2009-03-01

    Mowat-Wilson syndrome (MWS) is a developmental disorder presenting with mental retardation, delayed motor development, and a wide spectrum of clinical features. Hirschsprung's disease (HD) is associated in almost 50% of cases. This report aims to analyze the course of HD and to evaluate the clinical outcomes of these patients. Between 1997 and 2007, 110 patients presenting with HD were diagnosed and managed in our institution. Five of them presented the association of HD and MWS. Their records were reviewed retrospectively. All of the 5 patients have a genetic disorder specific of MWS (nonsense mutation or deletion on SIP1 gene, locus 2q22). Two patients underwent transanal endorectal pull-through procedure for classic rectosigmoid HD. Three patients were operated on for total colonic aganglionosis using Duhamel procedure. The median follow-up was 4 (range, 0.3-7) years. Only one patient is doing well (rectosigmoid HD). Two patients have a stoma diversion for severe motility disorders. Of the 3 total colonic aganglionosis, one still has repeated episodes of obstruction requiring total parenteral nutrition (TPN). The 2 others still have repeated episodes of enterocolitis. All patients required a prolonged TPN (32.5 months in average). Hirschsprung's disease associated with MWS is a severe condition. Even in case of short segment HD, patients can present motility disorder requiring a prolonged TPN. Physician and surgeon should be aware about the evolution of this rare condition.

  10. A case of spatial neglect dysgraphia in Wilson's Disease.

    Science.gov (United States)

    Auclair, Laurent; Siéroff, Eric; Kocer, Serdar

    2008-01-01

    We report here on a single neuropsychological case study of a young girl, KH, who presented with Wilson's Disease (WD) associated with a peripheral spatial neglect dysgraphia without major problems in the standard clinical tests of spatial neglect. Few studies have demonstrated a visuospatial deficit in WD and to date there has been no report of neglect syndrome arising from WD. However, recent studies have demonstrated that neglect is frequently associated with brain damage including the primary site of WD, the basal ganglia. KHs writing abilities were evaluated just after her admission to the rehabilitation department and 6 months later. The baseline evaluation demonstrated that KH had neglect dysgraphia with verbal stimuli (e.g., words or sentences) although her deficit was less evident in drawing multiple geometric shapes. Six months after the initial evaluation, KH showed evidence of neglect dysgraphia only when writing was associated with a secondary memory task. KHs writing performance is discussed with reference to previous cases of spatial neglect dysgraphia and in the context of spatial neglect. We suggest that the asymmetry between verbal writing and nonverbal drawing disturbances was caused by different attentional loads.

  11. ISRAEL-WILSON-PERJÉS Solutions in Heterotic String Theory

    Science.gov (United States)

    Herrera-Aguilar, Alfredo; Kechkin, Oleg

    We present a simple algorithm to obtain solutions that generalize the Israel-Wilson-Perjés class for the low energy limit of heterotic string theory toroidally compactified from D=d+3 to three dimensions. A remarkable map existing between the Einstein-Maxwell (EM) theory and the theory under consideration allows us to solve directly the equations of motion making use of the matrix Ernst potentials connected with the coset matrix of heterotic string theory.1 For the particular case d=1 (if we put n=6, the resulting theory can be considered as the bosonic part of the action of D=4, N=4 supergravity) we obtain explicitly a dyonic solution in terms of one real 2×2-matrix harmonic function and 2n real constants (n being the number of Abelian vector fields). By studying the asymptotic behavior of the field configurations we define the charges of the system. They satisfy the Bogomol'nyi-Prasad-Sommerfield (BPS) bound.

  12. Improvement Of Wilson Fermions And Twisted Mass Lattice Qcd

    CERN Document Server

    Wu, J M

    2005-01-01

    In order for Wilson fermions to be a competitive option to use in lattice QCD (LQCD) simulations, the large inherent discretization errors starting at O(a) (a being the lattice spacing) have to be removed. This can be accomplished through the Symanizk improvement program, where improvement terms have to be added to both the action and the operators of interest with coefficients appropriately chosen so that the rate of convergence to the continuum limit is quadratic in a. For this to be applicable to numerical simulations, improvement coefficients have to be determined non-perturbatively. A program for doing so has been pioneered by the Alpha collaboration. In this work, an extension of that program is made to improve all bilinear operators in QCD with two, three, and four flavours of non-degenerate quarks. With even numbers of quark flavours, an alternative approach is afforded by twisted mass LQCD (tmLQCD), where O(a) improvement in physical quantities can be achieved automatically at maximal twist. In this ...

  13. Mowat-Wilson syndrome presenting with fever-associated seizures.

    Science.gov (United States)

    Seo, Se Eun; Kim, Se Hee; Lee, Seung Tae; Choi, Jong Rak; Lee, Joon Soo; Kim, Heung Dong; Kang, Hoon-Chul

    2017-12-20

    Mowat-Wilson syndrome (MWS) is a disorder caused by mutations or deletions of the zinc finger E-box-binding homeobox 2 (ZEB2) gene. Diagnosis of MWS can be challenging to neurologists, because its manifestations are diverse and the spectrum of genetic mutations are broad. Here, we describe two patients with MWS who initially showed atypical forms of fever-triggered seizures during childhood. Both had characteristic facial features, cognitive impairment, and genito-urinary anomalies consistent with MWS. By performing targeted next-generation sequencing (NGS) using a gene panel for epilepsy, we were able to identify a nonsense mutation (c.1965C>A) in the ZEB2 gene of one patient and a frameshift mutation (c.2348dupC) in the other patient. Fever-induced seizures can be presenting signs of MWS. MWS should be considered in the differential diagnosis of fever-induced seizures, especially when the patient has distinctive facial features and multiple anomalies, including cardiac, genito-urinary, and eye defects.

  14. Book Review: Cheesman, Nick, Nicholas Farrelly, and Trevor Wilson: Debating Democratization in Myanmar

    Directory of Open Access Journals (Sweden)

    Marco Bünte

    2015-01-01

    Full Text Available Book Review of the edited volume: Cheesman, Nick, Nicholas Farrelly, and Trevor Wilson (eds (2014, Debating Democratization in Myanmar. Singapore: Institute of Southeast Asian Studies, ISBN: 978-981-4519-13-7, 381 pages

  15. Eugene Onegin the Cold War Monument: How Edmund Wilson Quarreled with Vladimir Nabokov

    National Research Council Canada - National Science Library

    Conley, Tim

    2014-01-01

    The tale of how Edmund Wilson quarreled with Vladimir Nabokov over the latter’s 1964 translation of Eugene Onegin can be instructively read as a politically charged event, specifically a “high culture...

  16. Relative exchangeable copper: a promising tool for family screening in Wilson disease.

    Science.gov (United States)

    Trocello, Jean-Marc; El Balkhi, Souleiman; Woimant, France; Girardot-Tinant, Nadège; Chappuis, Philippe; Lloyd, Carla; Poupon, Joël

    2014-04-01

    Family screening is a main step for the diagnosis in Wilson disease. This study was undertaken to evaluate the value of relative exchangeable copper for family screening. Data from family screening were collected from the French National Center of Reference for Wilson disease. Subjects who were first- or second-degree relatives of the index case underwent clinical examination and biological parameters. Of 127 subjects examined, copper abnormalities or low ceruloplasminemia were detected in 21 subjects, corresponding to 5 patients with Wilson disease, 14 heterozygous ATP7B carriers and 2 subjects with no ATP7B mutations. Relative exchangeable copper determination significantly discriminates heterozygous ATP7B carriers and subjects with no ATP7B mutations from WD patients with a cutoff of 15%. Exchangeable copper appears to be a promising tool for family screening in Wilson disease. © 2013 International Parkinson and Movement Disorder Society.

  17. SAFARI 2000 Vegetation and Soils, 1-Deg (Wilson and Henderson-Sellers)

    Data.gov (United States)

    National Aeronautics and Space Administration — This data set contains a subset for southern Africa of Wilson and Henderson-Sellers' Global Vegetation and Soils 1-degree data. The data are available in both ASCII...

  18. Wilson's disease: the 60th anniversary of Walshe's article on treatment with penicillamine.

    Science.gov (United States)

    Teive, Hélio A G; Barbosa, Egberto Reis; Lees, Andrew J

    2017-01-01

    This historical review describes Professor Walshe's seminal contribution to the treatment of Wilson's disease on the 60th anniversary of his pioneering article on penicillamine, the first effective treatment for the condition.

  19. LBA Regional Vegetation and Soils, 1-Degree (Wilson and Henderson-Sellers)

    Data.gov (United States)

    National Aeronautics and Space Administration — This data set is a subset of a global vegetation and soils data set by Wilson and Henderson-Sellers (1985a). The subset was created for the study area of the Large...

  20. LBA Regional Vegetation and Soils, 1-Degree (Wilson and Henderson-Sellers)

    Data.gov (United States)

    National Aeronautics and Space Administration — ABSTRACT: This data set is a subset of a global vegetation and soils data set by Wilson and Henderson-Sellers (1985a). The subset was created for the study area of...

  1. Asymptotic behavior of large polygonal Wilson loops in confining gauge theories

    CERN Document Server

    Pobylitsa, P V

    2016-01-01

    In the framework of effective string theory (EST), the asymptotic behavior of a large Wilson loop in confining gauge theories can be expressed via Laplace determinant with Dirichlet boundary condition on the Wilson contour. For a general polygonal region, Laplace determinant can be computed using the conformal anomaly and Schwarz-Christoffel transformation. One can construct ratios of polygonal Wilson loops whose large-size limit can be expressed via computable Laplace determinants and is independent of the (confining) gauge group. These ratios are computed for hexagon polygons both in EST and by Monte Carlo (MC) lattice simulations for the tree-dimensional lattice Z2 gauge theory (dual to Ising model) near its critical point. For large hexagon Wilson loops a perfect agreement is observed between the asymptotic EST expressions and the lattice MC results.

  2. Mowat-Wilson-syndrom hos tre danske børn

    DEFF Research Database (Denmark)

    Nissen, Karin Bækgaard; Søndergaard, Charlotte; Thelle, Thomas

    2011-01-01

    Mowat-Wilson syndrome (MWS) is an autosomal dominant intellectual disability syndrome characterised by unique facial features and congenital anomalies such as Hirschsprung disease, congenital heart defects, corpus callosum agenesis and urinary tract anomalies. Some cases also present epilepsy...

  3. Students' Perception of Live Lectures' Inherent Disadvantages

    Science.gov (United States)

    Petrovic, Juraj; Pale, Predrag

    2015-01-01

    This paper aims to provide insight into various properties of live lectures from the perspective of sophomore engineering students. In an anonymous online survey conducted at the Faculty of Electrical Engineering and Computing, University of Zagreb, we investigated students' opinions regarding lecture attendance, inherent disadvantages of live…

  4. Digital lecture recording: a cautionary tale.

    Science.gov (United States)

    Johnston, Amy N B; Massa, Helen; Burne, Thomas H J

    2013-01-01

    Increasing application of information technology including web-based lectures and live-lecture recording appears to have many advantages for undergraduate nursing education. These include greater flexibility, opportunity for students to review content on demand and the improved academic management of increasing class sizes without significant increase in physical infrastructure. This study performed a quasi-experimental comparison between two groups of nursing students undertaking their first anatomy and physiology course, where one group was also provided access to streaming of recorded copies of the live lectures and the other did not. For the course in which recorded lectures were available student feedback indicated overwhelming support for such provision with 96% of students having accessed recorded lectures. There was only a weak relationship between access of recorded lectures and overall performance in the course. Interestingly, the nursing students who had access to the recorded lectures demonstrated significantly poorer overall academic performance (P student demographics or other academic input, the data suggests that provision of recorded lectures requires improved and applied time management practices by students and caution on the part of the academic staff involved. Copyright © 2012 Elsevier Ltd. All rights reserved.

  5. Lecture Notes in Statistics. 3rd Semester

    DEFF Research Database (Denmark)

    The lecture note is prepared to meet the requirements of the curriculum for the 3rd smester course in statistics at the Aarhus School of Business.......The lecture note is prepared to meet the requirements of the curriculum for the 3rd smester course in statistics at the Aarhus School of Business....

  6. Extraversion, conscientiousness, goal management and lecturing ...

    African Journals Online (AJOL)

    The lecturing profession is a kind of profession that involves several tasks which must be carried out simultaneously, including, teaching, research, administration and community service. Hence, the ability and individual characteristics of lecturers will be of great importance in determining how to manage and achieve set ...

  7. University Lecturers' Professional Empowerment and Turnover in ...

    African Journals Online (AJOL)

    Hitherto, attention has not been paid to whether professional empowerment of the lecturers explains this phenomenon and whether it can help to curb it. Therefore, this study was conducted to analyse the level of professional empowerment provided to the lecturers and the way it relates to their turnover. Data was collected ...

  8. Individualization in a Lecture Hall Setting.

    Science.gov (United States)

    Halyard, Rebecca A.

    A two-quarter Human Anatomy and Physiology course for health-science students has been developed which incorporates the principles of individualization while maintaining the lecture hall setting. The lecture method contributes the following components to the course: (1) no special equipment or supplies; (2) personal interaction between instructor…

  9. Anthropocentric Video Segmentation for Lecture Webcasts

    Directory of Open Access Journals (Sweden)

    Raul Rojas

    2008-03-01

    Full Text Available Many lecture recording and presentation systems transmit slides or chalkboard content along with a small video of the instructor. As a result, two areas of the screen are competing for the viewer's attention, causing the widely known split-attention effect. Face and body gestures, such as pointing, do not appear in the context of the slides or the board. To eliminate this problem, this article proposes to extract the lecturer from the video stream and paste his or her image onto the board or slide image. As a result, the lecturer acting in front of the board or slides becomes the center of attention. The entire lecture presentation becomes more human-centered. This article presents both an analysis of the underlying psychological problems and an explanation of signal processing techniques that are applied in a concrete system. The presented algorithm is able to extract and overlay the lecturer online and in real time at full video resolution.

  10. Collide@CERN - public lecture

    CERN Multimedia

    2012-01-01

    CERN, the Republic and Canton of Geneva and the City of Geneva are delighted to invite you to a public lecture by Gilles Jobin, first winner of the Collide@CERN Geneva Dance and Performance Artist-in-residence Prize, and his CERN inspiration partner, Joao Pequenao. They will present their work in dance and science at the Globe of Science and Innovation on Wednesday, 23 May 2012 at 7 p.m. (doors open at 6.30 p.m.).   
                                                  Programme 19:00 Opening address by - Professor Rolf-Dieter Heuer, CERN Director-General, - Ariane Koek...

  11. Lecture 3: Web Application Security

    CERN Multimedia

    CERN. Geneva

    2013-01-01

    Computer security has been an increasing concern for IT professionals for a number of years, yet despite all the efforts, computer systems and networks remain highly vulnerable to attacks of different kinds. Design flaws and security bugs in the underlying software are among the main reasons for this. This lecture focuses on security aspects of Web application development. Various vulnerabilities typical to web applications (such as Cross-site scripting, SQL injection, cross-site request forgery etc.) are introduced and discussed. Sebastian Lopienski is CERN’s deputy Computer Security Officer. He works on security strategy and policies; offers internal consultancy and audit services; develops and maintains security tools for vulnerability assessment and intrusion detection; provides training and awareness raising; and does incident investigation and response. During his work at CERN since 2001, Sebastian has had various assignments, including designing and developing software to manage and support servic...

  12. Une lecture anglophone et marxiste.

    Directory of Open Access Journals (Sweden)

    Kevin Cox

    2006-11-01

    Full Text Available Vous m’avez invité 1 à faire une lecture critique du Dictionnaire de la géographie et de l’espace des sociétés . Je pense qu’il s’agit d’un bon ouvrage, très utile, très stimulant et, pour un géographe anglophone, très représentatif. C’est le genre de dictionnaire dont on a besoin. Il s’immerge dans les débats actuels et il est nourri de ces débats. C’est un ouvrage ambitieux qui va au-delà de la simple définition des objets géographiques comme « ville » ou ...

  13. Academic Training Lecture Regular Programme

    CERN Multimedia

    2012-01-01

    Ultra-High Energy Cosmic Rays (1/3), by Maria Teresa Dova (Universidad Nacional de La Plata & CONICET, Argentina).   Wednesday, April 25, 2012 from 11:00 to 12:00 (Europe/Zurich) at CERN (500-1-001 - Main Auditorium ) The origin of the highest energy cosmic rays (UHECR) with energies above 1000 TeV, is still unknown. The discovery of their sources will reveal the engines of the most energetic astrophysical accelerators in the universe. In these lectures we present the recent observational results from HiRes, Telescope Array and Pierre Auger Observatory as well as (some of) the possible astrophysical origins of UHECR. These experiments deal with particle interactions at energies orders of magnitude higher than achieved in terrestrial accelerators. Organised by Luis Alvarez-Gaume.

  14. Lecture notes on diophantine analysis

    CERN Document Server

    Zannier, Umberto

    2014-01-01

    These lecture notes originate from a course delivered at the Scuola Normale in Pisa in 2006. Generally speaking, the prerequisites do not go beyond basic mathematical material and are accessible to many undergraduates. The contents mainly concern diophantine problems on affine curves, in practice describing the integer solutions of equations in two variables. This case historically suggested some major ideas for more general problems. Starting with linear and quadratic equations, the important connections with Diophantine Approximation are presented and Thue's celebrated results are proved in full detail. In later chapters more modern issues on heights of algebraic points are dealt with, and applied to a sharp quantitative treatment of the unit equation. The book also contains several Supplements, hinted exercises and an Appendix on recent work on heights.

  15. Data mining approach to the evaluation of diagnostic tests in Wilson disease

    Science.gov (United States)

    Plutecki, Michal M.; Dądalski, Maciej; Socha, Piotr; Mulawka, Jan J.

    2009-06-01

    The purpose of this paper is to figure out a new, better than so-far-known, evaluation method of diagnostic tests in Wilson disease. In order to find the most interesting classification models various data mining techniques were applied to real, suffering from Wilson disease, set of patients. It occurred that a combination of two classification algorithms with its implementations in Weka environment may significantly increase classification ability.

  16. Determination of low-energy constants of Wilson chiral perturbation theory

    Energy Technology Data Exchange (ETDEWEB)

    Herdoiza, Gregorio [Mainz Univ. (Germany). Inst fuer Kernphysik, PRISMA Cluster of Excellence; Univ. Autonoma de Madrid, Contoblanco (Spain). Dept. de Fisica Teorica; Univ. Autonoma de Madrid (Spain). Inst. de Fisica Teorica UAM/CSIC; Jansen, Karl [Deutsches Elektronen-Synchrotron (DESY), Zeuthen (Germany). John von Neumann-Inst. fuer Computing NIC; Univ. Cyprus, Nicosia (Cyprus). Dept. of Physics; Michael, Chris [Liverpool Univ. (United Kingdom). Theoretical Physics Division; Ottnad, Konstantin; Urbach, Carsten [Bonn Univ. (Germany). Helmholtz-Institut fuer Strahlen und Kernphysik; Univ. Bonn (Germany). Bethe Center for Theoretical Physics; Collaboration: European Twisted Mass Collaboration

    2013-03-15

    By matching Wilson twisted mass lattice QCD determinations of pseudoscalar meson masses to Wilson Chiral Perturbation Theory we determine the low-energy constants W{sub 6}{sup '}, W{sub 8}{sup '} and their linear combination c{sub 2}. We explore the dependence of these low-energy constants on the choice of the lattice action and on the number of dynamical flavours.

  17. The epsilon regime of chiral perturbation theory with Wilson-type fermions

    Energy Technology Data Exchange (ETDEWEB)

    Jansen, K. [Deutsches Elektronen-Synchrotron (DESY), Zeuthen (Germany). John von Neumann-Inst. fuer Computing NIC; Shindler, A. [Liverpool Univ. (United Kingdom). Theoretical Physics Division

    2009-11-15

    In this proceeding contribution we report on the ongoing effort to simulate Wilson-type fermions in the so called epsilon regime of chiral perturbation theory (cPT).We present results for the chiral condensate and the pseudoscalar decay constant obtained with Wilson twisted mass fermions employing two lattice spacings, two different physical volumes and several quark masses. With this set of simulations we make a first attempt to estimate the systematic uncertainties. (orig.)

  18. Wilson Loops and Scattering Amplitudes in Supersymmetric Field and String Theories

    OpenAIRE

    Marmiroli, Daniele

    2012-01-01

    The long-standing problem of finding weak-strong coupling interpolating observables for supersymmetric Chern-Simons theories in three dimensions is analysed from the point of view of BPS Wilson loop operators. Analizziamo l'annoso problema della determinazione di funzioni interpolanti tra i regimi di accoppiamento debole e accoppiamento forte in teorie di Chern-Simons supersimmetriche in tre dimensioni dal punto di vista di operatori di Wilson BPS.

  19. Atomic Absorption Spectrometry in Wilson's Disease and Its Comparison with Other Laboratory Tests and Paraclinical Findings

    OpenAIRE

    Mahjoub, Fatemeh; Fereiduni, Rana; Jahanzad, Isa; Farahmand, Fatemeh; Monajemzadeh, Maryam; Najafi, Mehri

    2012-01-01

    Objective Wilson's disease (WD) is an autosomal recessive disease with genetic abnormality on chromosome 13 causing defect in copper metabolism and increased copper concentration in liver, central nervous system and other organs, which causes different clinical manifestations. The aim of this study was to determine the sensitivity of different clinical and paraclinical tests for diagnosis of Wilson's disease. Methods Paraffin blocks of liver biopsy from 41 children suspicious of WD were colle...

  20. Parton densities in quantum chromodynamics gauge invariance, path-dependence and Wilson lines

    CERN Document Server

    Cherednikov, Igor O

    2016-01-01

    The purpose of this book is to give a systematic pedagogical exposition of the quantitative analysis of Wilson lines and loops in quantum chromodynamics. Using techniques from the previous volume (Wilson Lines in Quantum Field Theory, 2014), ab initio techniques are developed and practical tools for their implementation presented. An emphasis is put on their renormalization and on implications on processes observable at experimental facilities.

  1. Lecture notes for criticality safety

    Energy Technology Data Exchange (ETDEWEB)

    Fullwood, R.

    1992-03-01

    These lecture notes for criticality safety are prepared for the training of Department of Energy supervisory, project management, and administrative staff. Technical training and basic mathematics are assumed. The notes are designed for a two-day course, taught by two lecturers. Video tapes may be used at the options of the instructors. The notes provide all the materials that are necessary but outside reading will assist in the fullest understanding. The course begins with a nuclear physics overview. The reader is led from the macroscopic world into the microscopic world of atoms and the elementary particles that constitute atoms. The particles, their masses and sizes and properties associated with radioactive decay and fission are introduced along with Einstein's mass-energy equivalence. Radioactive decay, nuclear reactions, radiation penetration, shielding and health-effects are discussed to understand protection in case of a criticality accident. Fission, the fission products, particles and energy released are presented to appreciate the dangers of criticality. Nuclear cross sections are introduced to understand the effectiveness of slow neutrons to produce fission. Chain reactors are presented as an economy; effective use of the neutrons from fission leads to more fission resulting in a power reactor or a criticality excursion. The six-factor formula is presented for managing the neutron budget. This leads to concepts of material and geometric buckling which are used in simple calculations to assure safety from criticality. Experimental measurements and computer code calculations of criticality are discussed. To emphasize the reality, historical criticality accidents are presented in a table with major ones discussed to provide lessons-learned. Finally, standards, NRC guides and regulations, and DOE orders relating to criticality protection are presented.

  2. Lecture notes for criticality safety

    Energy Technology Data Exchange (ETDEWEB)

    Fullwood, R.

    1992-03-01

    These lecture notes for criticality safety are prepared for the training of Department of Energy supervisory, project management, and administrative staff. Technical training and basic mathematics are assumed. The notes are designed for a two-day course, taught by two lecturers. Video tapes may be used at the options of the instructors. The notes provide all the materials that are necessary but outside reading will assist in the fullest understanding. The course begins with a nuclear physics overview. The reader is led from the macroscopic world into the microscopic world of atoms and the elementary particles that constitute atoms. The particles, their masses and sizes and properties associated with radioactive decay and fission are introduced along with Einstein`s mass-energy equivalence. Radioactive decay, nuclear reactions, radiation penetration, shielding and health-effects are discussed to understand protection in case of a criticality accident. Fission, the fission products, particles and energy released are presented to appreciate the dangers of criticality. Nuclear cross sections are introduced to understand the effectiveness of slow neutrons to produce fission. Chain reactors are presented as an economy; effective use of the neutrons from fission leads to more fission resulting in a power reactor or a criticality excursion. The six-factor formula is presented for managing the neutron budget. This leads to concepts of material and geometric buckling which are used in simple calculations to assure safety from criticality. Experimental measurements and computer code calculations of criticality are discussed. To emphasize the reality, historical criticality accidents are presented in a table with major ones discussed to provide lessons-learned. Finally, standards, NRC guides and regulations, and DOE orders relating to criticality protection are presented.

  3. Double-winding Wilson loops in the S U (N ) Yang-Mills theory

    Science.gov (United States)

    Matsudo, Ryutaro; Kondo, Kei-Ichi

    2017-11-01

    We consider double-winding, triple-winding, and multiple-winding Wilson loops in the S U (N ) Yang-Mills gauge theory. We examine how the area-law falloff of the vacuum expectation value of a multiple-winding Wilson loop depends on the number of color N . In sharp contrast to the difference-of-areas law recently found for a double-winding S U (2 ) Wilson loop average, we show irrespective of the spacetime dimensionality that a double-winding S U (3 ) Wilson loop follows a novel area law which is neither difference-of-areas nor sum-of-areas law for the area-law falloff and that the difference-of-areas law is excluded and the sum-of-areas law is allowed for S U (N ) (N ≥4 ), provided that the string tension obeys the Casimir scaling for the higher representations. Moreover, we extend these results to arbitrary multiple-winding Wilson loops. Next, we argue that the area law follows a novel law, which is neither sum-of-areas nor difference-of-areas law when N ≥3 . In fact, such a behavior is exactly derived in the S U (N ) Yang-Mills theory in the two-dimensional spacetime. Finally, we introduce new Wilson loops whose averages are expected to follow the difference-of-areas law even in the S U (N ) Yang-Mills theory for N ≥3 .

  4. Mendelism: New Insights from Gregor Mendel's Lectures in Brno.

    Science.gov (United States)

    Zhang, Hui; Chen, Wen; Sun, Kun

    2017-09-01

    Interpretation of Gregor Mendel's work has previously been based on study of his published paper "Experiments in Plant Hybridization." In contrast, the lectures that he gave preceding publication of this work have been largely neglected for more than 150 years. Here, we report on and interpret the content of Mendel's previous two lectures, as they were reported in a local newspaper. We comprehensively reference both the text of his paper and the historical background of his experiments. Our analysis shows that while Mendel had inherited the traditional research program on interspecific hybridization in plants, he introduced the novel method of ratio analysis for representing the variation of unit-characters among offspring of hybrids. His aim was to characterize and explain the developmental features of the distributional pattern of unit-characters in two series of hybrid experiments, using self-crosses and backcrosses with parents. In doing so, he not only answered the question of what the unit-characters were and the nature of their hierarchical classification, but also successfully inferred the numerical principle of unit-character transmission from generation to generation. He also established the nature of the composition and behaviors of reproductive cells from one generation to the next. Here we highlight the evidence from Mendel's lectures, clearly announcing that he had discovered the general law of cross-generation transmission of unit-characters through reproductive cells containing unit-factors. The recovered content of these previous lectures more accurately describes the work he performed with his garden peas than his published paper and shows how he first presented it in Brno. It is thus an invaluable resource for understanding the origin of the science of genetics. Copyright © 2017 by the Genetics Society of America.

  5. Lectures on Higgs Boson Physics in the Standard Model and Beyond

    CERN Document Server

    Wells, James D

    2009-01-01

    These lectures focus on the structure of various Higgs boson theories. Topics in the first lectures include: mass generation in chiral theories, spontaneous symmetry breaking, neutrino masses, perturbative unitarity, vacuum stability, vacuum alignment, flavor changing neutral current solutions with multiple Higgs doublets, analysis of type I theory with Z2 symmetry, and rephasing symmetries. After an Essay on the Hierarchy Problem, additional topics are covered that more directly relate to naturalness of the electroweak theory. Emphasis is on their connection to Higgs boson physics. Topics in these later lectures include: supersymmetry, supersymmetric Higgs sector in the Runge basis, leading-order radiative corrections of supersymmetric light Higgs boson mass, theories of extra dimensions, and radion mixing with the Higgs boson in warped extra dimensions. And finally, one lecture is devoted to Higgs boson connections to the hidden sector.

  6. Dystonic Dysarthria in Wilson Disease: Efficacy of Zolpidem

    Directory of Open Access Journals (Sweden)

    Aurélia Poujois

    2017-10-01

    Full Text Available Wilson disease (WD is a rare genetic disorder characterized by copper overload in the liver and the brain. Neurological presentations are mainly related to the accumulation of copper in the basal ganglia, the brainstem, and the cerebellum. Dysarthria is a frequent symptom, with dystonic, spastic, or parkinsonian components and is usually resistant to medical or voice rehabilitation therapies. Here, we report the case of a patient with WD diagnosed at the age of 12, who presented a severe and constant dysarthria from dystonic origin which was unresponsive to benzodiazepines and anticholinergic drugs. When she was 25-year-old, she tried zolpidem at bedtime for sleeping difficulties and reported a paradoxical effect of this drug on her voice. To confirm the effect of zolpidem on her dystonic dysarthria, we realized a full evaluation of her dysarthria at baseline without zolpidem and after 4 days of treatment by 10 mg twice a day. Lexical access was evaluated by the semantic fluency; dysarthria by the Intelligibility Score, the spontaneous speech and reading rates, the maximum phonation time on the sustained vowel [a] and by a perceptive evaluation. Two hours after the intake of zolpidem, improvement of all the parameters tested, with the exception of the maximum phonation time, was observed. Semantic fluency increased by 59%, the spontaneous speech rate by 88% and the reading rate by 76%. General dystonia remained unchanged and the tolerance of zolpidem was satisfactory. Since then, the patient takes zolpidem 5 mg five times a day, and 4 years later shows persistent improvement in oral communication and a good drug tolerance. In this single-case study, we showed that regular daytime intake of zolpidem could have a persisting effect on a complex dystonic dysarthria that was resistant to usual medical treatments.

  7. Lectures on probability and statistics. Revision

    Energy Technology Data Exchange (ETDEWEB)

    Yost, G.P.

    1985-06-01

    These notes are based on a set of statistics lectures delivered at Imperial College to the first-year postgraduate students in High Energy Physics. They are designed for the professional experimental scientist. They begin with the fundamentals of probability theory, in which one makes statements about the set of possible outcomes of an experiment, based upon a complete a priori understanding of the experiment. For example, in a roll of a set of (fair) dice, one understands a priori that any given side of each die is equally likely to turn up. From that, we can calculate the probabilty of any specified outcome. They finish with the inverse problem, statistics. Here, one begins with a set of actual data (e.g., the outcomes of a number of rolls of the dice), and attempts to make inferences about the state of nature which gave those data (e.g., the likelihood of seeing any given side of any given die turn up). This is a much more difficult problem, of course, and one's solutions often turn out to be unsatisfactory in one respect or another. Hopefully, the reader will come away from these notes with a feel for some of the problems and uncertainties involved. Although there are standard approaches, most of the time there is no cut and dried ''best'' solution - ''best'' according to every criterion.

  8. A survey of first-year biology student opinions regarding live lectures and recorded lectures as learning tools.

    Science.gov (United States)

    Simcock, D C; Chua, W H; Hekman, M; Levin, M T; Brown, S

    2017-03-01

    A cohort of first-year biology students was surveyed regarding their opinions and viewing habits for live and recorded lectures. Most respondents (87%) attended live lectures as a rule (attenders), with 66% attending more than two-thirds of the lectures. In contrast, only 52% accessed recordings and only 13% viewed more than two-thirds of the available recordings. Respondents regarded lectures as efficient for information delivery (75%), and 89% enjoyed live lectures because they were useful for learning (89%), understanding coursework (94%), and keeping up with the subject (93%). Lecture enjoyment was driven less by entertainment (34%) or interaction with the lecturers (47%), although most students preferred an entertaining lecturer to a factual expert (72%). Exam marks were positively correlated with the number of lectures attended (P 0.05). Lecture attenders mostly missed lectures to complete assessments during the same week (68%), whereas nonattenders were more likely to miss lectures due to outside commitments or preference for study from books or recorded lectures (P < 0.001). Recordings were used to replace missed lectures (64%), rather than for revision, and were viewed mostly alone (96%) in one sitting (65%). Only 22% of respondents agreed that some lectures could be replaced by recordings, but 59% agreed with having some videoconference lectures from experts on another campus. Overall, this cohort showed a clear preference for live lectures over recordings, with limited support for synchronous videoconference lectures. Copyright © 2017 the American Physiological Society.

  9. Lectures Abandoned: Active Learning by Active Seminars

    DEFF Research Database (Denmark)

    Christensen, Henrik Bærbak; Corry, Aino Vonge

    2012-01-01

    Traditional lecture-based courses are widely criticised for be- ing less eective in teaching. The question is of course what should replace the lectures and various active learning tech- niques have been suggested and studied. In this paper, we report on our experiences of redesigning a software ......- tive seminars as a replacement of traditional lectures, an activity template for the contents of active seminars, an ac- count on how storytelling supported the seminars, as well as reports on our and the students' experiences....

  10. Paul Dirac lectures at CERN

    CERN Multimedia

    CERN Bulletin

    2010-01-01

    When a group of physicists entered the Main Auditorium, during the evening of 29 June, they felt they had opened a time portal.   Paul Dirac in front of a blackboard showing his formula. ©Sandra Hoogeboom An attentive audience, dressed in early 1900 costumes, were watching a lecture by the elusive Paul Dirac, presenting for the first time his famous formula on the blackboard. Paul Adrien Maurice Dirac (1902-1984) was a British mathematical physicist at Cambridge, and one of the "fathers" of quantum mechanics. When he first wrote it, in 1928, Dirac was not sure what his formula really meant. As demonstrated by Andersson four year later, what Dirac had written on the blackboard was the first definition of a positron, hence he is credited with having anticipated the existence of antimatter. The actor John Kohl performs as Paul Dirac. ©Sandra Hoogeboom What the group of puzzled physicists were really observing when they entered the CERN Auditorium was the shoo...

  11. Lectures on advances in combinatorics

    CERN Document Server

    Ahlswede, Rudolf

    2008-01-01

    The main focus of these lectures is basis extremal problems and inequalities – two sides of the same coin. Additionally they prepare well for approaches and methods useful and applicable in a broader mathematical context. Highlights of the book include a solution to the famous 4m-conjecture of Erdös/Ko/Rado 1938, one of the oldest problems in combinatorial extremal theory, an answer to a question of Erdös (1962) in combinatorial number theory "What is the maximal cardinality of a set of numbers smaller than n with no k+1 of its members pair wise relatively prime?", and the discovery that the AD-inequality implies more general and sharper number theoretical inequalities than for instance Behrend's inequality. Several concepts and problems in the book arise in response to or by rephrasing questions from information theory, computer science, statistical physics. The interdisciplinary character creates an atmosphere rich of incentives for new discoveries and lends Ars Combinatoria a special status in mathemat...

  12. Developing Entrepreneurial Competences in University Lecturers ...

    African Journals Online (AJOL)

    Developing Entrepreneurial Competences in University Lecturers: Obafemi Awolowo University Experience. ... about entrepreneurship, and on how to develop enthusiasm for entrepreneurship among students. Keywords: Entrepreneurship; Competences; Pedagogy; Entrepreneurship education; enterprising mindset ...

  13. Recently Published Lectures and Tutorials for ATLAS

    CERN Multimedia

    J. Herr

    2006-01-01

    As reported in the September 2004 ATLAS eNews, the Web Lecture Archive Project, a collaboration between the University of Michigan and CERN, has developed a synchronized system for recording and publishing educational multimedia presentations, using the Web as medium. The current system, including future developments for the project and the field in general, was recently presented at the CHEP 2006 conference in Mumbai, India. The relevant presentations and papers can be found here: The Web Lecture Archive Project A Web Lecture Capture System with Robotic Speaker Tracking This year, the University of Michigan team has been asked to record and publish all ATLAS Plenary sessions, as well as a large number of Physics and Computing tutorials. A significant amount of this material has already been published and can be accessed via the links below. All lectures can be viewed on any major platform with any common internet browser, either via streaming or local download (for limited bandwidth). Please enjoy the l...

  14. Recently Published Lectures and Tutorials for ATLAS

    CERN Multimedia

    Goldfarb, S.

    2006-01-01

    As reported in the September 2004 ATLAS eNews, the Web Lecture Archive Project, WLAP, a collaboration between the University of Michigan and CERN, has developed a synchronized system for recording and publishing educational multimedia presentations, using the Web as medium. The current system, including future developments for the project and the field in general, was recently presented at the CHEP 2006 conference in Mumbai, India. The relevant presentations and papers can be found here: The Web Lecture Archive Project. A Web Lecture Capture System with Robotic Speaker Tracking This year, the University of Michigan team has been asked to record and publish all ATLAS Plenary sessions, as well as a large number of Physics and Computing tutorials. A significant amount of this material has already been published and can be accessed via the links below. All lectures can be viewed on any major platform with any common internet browser, either via streaming or local download (for limited bandwidth). Please e...

  15. Hadron physics at Fermilab. [Review lectures

    Energy Technology Data Exchange (ETDEWEB)

    Ferbel, T.

    1976-08-30

    Recent experimental results from studies of hadron interactions at Fermilab are surveyed. Elastic, total and charge-exchange cross section measurements, diffractive phenomena, and inclusive production, using nuclear as well as hydrogen targets, are discussed in these lectures.

  16. Genetic Algorithms to Optimizatize Lecturer Assessment's Criteria

    Science.gov (United States)

    Jollyta, Deny; Johan; Hajjah, Alyauma

    2017-12-01

    The lecturer assessment criteria is used as a measurement of the lecturer's performance in a college environment. To determine the value for a criteriais complicated and often leads to doubt. The absence of a standard valuefor each assessment criteria will affect the final results of the assessment and become less presentational data for the leader of college in taking various policies relate to reward and punishment. The Genetic Algorithm comes as an algorithm capable of solving non-linear problems. Using chromosomes in the random initial population, one of the presentations is binary, evaluates the fitness function and uses crossover genetic operator and mutation to obtain the desired crossbreed. It aims to obtain the most optimum criteria values in terms of the fitness function of each chromosome. The training results show that Genetic Algorithm able to produce the optimal values of lecturer assessment criteria so that can be usedby the college as a standard value for lecturer assessment criteria.

  17. Lecture Notes in Statistics. 3rd Semester

    DEFF Research Database (Denmark)

    The lecture note is prepared to meet the requirements for the 3rd semester course in statistics at the Aarhus School of Business. It focuses on multiple regression models, analysis of variance, and log-linear models.......The lecture note is prepared to meet the requirements for the 3rd semester course in statistics at the Aarhus School of Business. It focuses on multiple regression models, analysis of variance, and log-linear models....

  18. Four lectures on legal anthropology - 2008

    OpenAIRE

    Macfarlane, Alan

    2008-01-01

    The lectures were given by Alan Macfarlane to second and third year students in Cambridge university department of social anthropology doing a special paper on Legal Anthropology in February 2008 Four lectures on aspects of legal anthropology. The first on law and justice in Japan; the second on moral panics and terrorism; the third on foundations and history of legal anthropology (part one); the fourth on the same (part two)

  19. Lectures on special topics in legal anthropology

    OpenAIRE

    Macfarlane, Alan

    2008-01-01

    The lectures were given by Alan Macfarlane to second and third year students in Cambridge University department of social anthropology doing a special paper on Legal Anthropology in February 2008. Four lectures on aspects of legal anthropology. The first on law and justice in Japan; the second on moral panics and terrorism; the third on foundations and history of legal anthropology (part one); the fourth on the same (part two)

  20. Educational Effect of Online Lecture using Streaming Technology

    Science.gov (United States)

    Akiyama, Hidenori; Teramoto, Akemi; Kozono, Kazutake

    A conventional lecture on Laser Engineering had been done in a lecture room till 1999. A content using on-demand streaming method was made for an online lecture of Laser Engineering in 2000. The figures and equations used on the conventional lecture and the voice recorded for the online lecture were converted to the real media. Then an online lecture has been provided to students by using a Helix Universal Server. The trial of the online lecture was done only for the students who wanted to take the online lecture course in 2000. The online lectures have been recognized as the credits for graduation by the change of a law since 2001. About 100 students have registered the online lecture of Laser Engineering every year since 2001. Here, three years' questionnaire surveys of the online lecture are summarized, and results of examinations on the conventional lecture for two years and on the online lecture for three years are compared. It is recognized for the lecture of Laser Engineering that the educational effect of the online lecture is comparable to or better than that of the conventional lecture.

  1. The Lecture and Instructional Design: A Contradiction in Terms?

    Science.gov (United States)

    Sweeney, John J.; Reigeluth, Charles M.

    1984-01-01

    Discusses advantages and disadvantages of the lecture method as an instructional form; circumstances where lectures serve a useful purpose; the general lecture model, which includes an introduction, presentation, and summary; and three variations on this general model--interactive, demonstrational, and interactive demonstration lectures. (MBR)

  2. The Impact of Online Lecture Recordings on Student Performance

    Science.gov (United States)

    Williams, Andrew; Birch, Elisa; Hancock, Phil

    2012-01-01

    The use of online lecture recordings as a supplement to physical lectures is an increasingly popular tool at many universities. This paper combines survey data with student record data for students in a "Microeconomics Principles" class to examine the relative effects of lecture attendance and online lecture recordings. The main finding…

  3. Flipped classroom or an active lecture?

    Science.gov (United States)

    Pickering, James D; Roberts, David J H

    2018-01-01

    Recent changes in anatomy education have seen the introduction of flipped classrooms as a replacement to the traditional didactic lecture. This approach utilizes the increasing availability of digital technology to create learning resources that can be accessed prior to attending class, with face-to-face sessions then becoming more student-centered via discussion, collaborative learning, and problem-solving activities. Although this approach may appear intuitive, this viewpoint commentary presents a counter opinion and highlights a simple alternative that utilizes evidence-based active learning approaches as part of the traditional lecture. The active lecture takes the traditional lecture, and (1) ensures the lecture content is relevant and has clear objectives, (2) contains lecture material that is designed according to the latest evidence-base, (3) complements it with additional supplementary material, (4) creates space to check prior understanding and knowledge levels, and (5) utilizes suitable technology to facilitate continual engagement and interaction. Clin. Anat. 31:118-121, 2018. © 2017 Wiley Periodicals, Inc. © 2017 Wiley Periodicals, Inc.

  4. 2000-2001 ACADEMIC TRAINING PROGRAMME 1ST TERM - 11 SEPTEMBER-22 DECEMBER 2000 LECTURE SERIES FOR POSTGRADUATE STUDENTS

    CERN Multimedia

    TRAINING & DEVELOPMENT; Françoise Benz; Tel. 73127

    2000-01-01

    Introduction to Particle Accelerators by E.J.N. Wilson / CERN-AC 11, 12, 13, 14, 15 September 10:00-12:00 - Auditorium 11, 12, 13, 14 and Council Chamber 15 September (early starting time) Introduction to Field Theory by R. Kleiss, Univ. of Nijmegen, NL 23, 24, 25, 26, 27 October 10:00-12:00 - Auditorium (early starting time) Introduction to QCD by B. Webber, Univ. of Cambridge, GB 30, 31 October, 1, 2, 3 November 10:00-12:00 - Auditorium (early starting time) Introduction to the Standard Model by G. Ridolfi (TH-Division) 20, 21, 22, 23 & 24 November 10:00-12:00 - Auditorium (early starting time) Beyond the Standard Model by G. Giudice (TH-Division) 11, 12, 13, 14, 15 December 11:00-12:00 - Auditorium The lectures are open to all those interested, without application. The abstract of the lectures, as well as any change to the above information (title, dates, time, place etc.) will be published in the CERN bulletin, the WWW, and by Notices before each term and for each series of lectures.

  5. Students’ opinions about modern lecture: development path

    Directory of Open Access Journals (Sweden)

    Tatyana A. Astashova

    2017-01-01

    Full Text Available As an objective of the research, the author set the task of identifying students’ opinion and opinion of lecturers about the purpose of the lectures at the university, about the role of the lecturer and preferred form of lectures. As a result of the research, it was necessary to answer the following important questions: What are the objectives of the lecture and the role of the lecturer? Which lectures are more preferable: traditional or interactive? What do lecturers expect from the lecture, do they consider it an advantage or an unnecessary educational activity?The materials were developed for the survey (questionnaire to conduct the research and analyze the results obtained. The students were surveyed before training and after completion of the semester. The study involved 200 students of all areas of Mechanics and Technology Faculty of Novosibirsk State Technical University. Statistical analysis was used for the analysis of the results.As a result, the experiment revealed nonconformity of opinions of students about the purpose of the lecture and the role of a lecturer before the training and after the end of the semester. Lectures, according to students, should help to implement all kinds of practical and independent assignments.Educational standards imply a reduction in the hours of classroom training and an increase in independent work, and the majority of students are not ready (do not want to to study the materials on the topics of discipline completely independently or partially.It revealed a contradiction in opinion, what form of organization of the lecture classes is more interesting to students, which can increase the motivation of the visit and work on the lectures.The technology of designing the educational process in the conditions of the mixed training is proposed, applying the technological map.The technological map is presented in the form of stages of designing the educational process, including recommendations on the use of

  6. Argonne lectures on particles accelerator magnets

    Energy Technology Data Exchange (ETDEWEB)

    Devred, A

    1999-09-01

    The quest for elementary particles has promoted the development of particle accelerators producing beams of increasingly higher energies. In a synchrotron, the particle energy is directly proportional to the product of the machine's radius times the bending magnets' field strength. Present proton experiments at the TeV scale require facilities with circumferences ranging from a few to tens of kilometers and relying on a large number (several hundred to several thousand) high field dipole magnets and high field gradient quadrupole magnets. These electro-magnets use high-current-density, low-critical-temperature superconducting cables and are cooled down at liquid helium temperature. They are among the most costly and the most challenging components of the machine. After explaining what are the various types of accelerator magnets and why they are needed (lecture 1), we briefly recall the origins of superconductivity and we review the parameters of existing superconducting particle accelerators (lecture 2). Then, we review the superconducting materials that are available at industrial scale (chiefly, NbTi and Nb{sub 3}Sn) and we explain in details the manufacturing of NbTi wires and cables (lecture 3). We also present the difficulties of processing and insulating Nb{sub 3}Sn conductors, which so far have limited the use of this material in spite of its superior performances. We continue by discussing the two dimensional current distributions which are the most appropriate for generating pure dipole and quadrupole fields and we explain how these ideal distributions can be approximated by so called cos{theta} and cos 2{theta} coil designs (lecture 4). We also present a few alternative designs which are being investigated and we describe the difficulties of realizing coil ends. Next, we present the mechanical design concepts that are used in existing accelerator magnets (lecture 5) and we describe how the magnets are assembled (lecture 6). Some of the toughest

  7. Envisioning the Transformative Role of IT in Lectures

    Directory of Open Access Journals (Sweden)

    Telmo Zarraonandia

    2013-02-01

    Full Text Available One of the most widely used methods for teaching is the lecture. During the last few decades lecturers and students have taken advantage of the progressive introduction of new technology for supporting these lectures. As this trend is very likely to continue, in this paper we will try to anticipate some possible technology enriched future lecture scenarios. We also present ALFs, a system which aims to improve the communication between participants in a lecture making use of augmented reality techniques.

  8. Nucleon structure in terms of OPE with non-perturbative Wilson coefficients

    Energy Technology Data Exchange (ETDEWEB)

    Bietenholz, W. [Deutsches Elektronen-Synchrotron (DESY), Zeuthen (Germany). John von Neumann-Inst. fuer Computing NIC]|[Regensburg Univ. (Germany). Inst. fuer Physik 1 - Theoretische Physik; Cundy, N.; Goeckeler, M. [Regensburg Univ. (Germany). Inst. fuer Physik 1 - Theoretische Physik; Horsley, R.; Zanotti, J.M. [Edinburgh Univ. (United Kingdom). School of Physics; Perlt, H.; Schiller, A. [Leipzig Univ. (Germany). Inst. fuer Theoretische Physik; Pleiter, D.; Schierholz, G. [Deutsches Elektronen-Synchrotron (DESY), Zeuthen (Germany). John von Neumann-Inst. fuer Computing NIC; Rakow, P.E.L. [Liverpool Univ. (United Kingdom). Theoretical Physics Division, Dept. of Mathematical Sciences

    2008-10-15

    Lattice calculations could boost our understanding of Deep Inelastic Scattering by evaluating moments of the Nucleon Structure Functions. To this end we study the product of electromagnetic currents between quark states. The Operator Product Expansion (OPE) decomposes it into matrix elements of local operators (depending on the quark momenta) and Wilson coefficients (as functions of the larger photon momenta). For consistency with the matrix elements, we evaluate a set of Wilson coefficients non-perturbatively, based on propagators for numerous momentum sources, on a 24{sup 3} x 48 lattice. The use of overlap quarks suppresses unwanted operator mixing and lattice artifacts. Results for the leading Wilson coefficients are extracted by means of Singular Value Decomposition. (orig.)

  9. Atp7b-/- mice as a model for studies of Wilson's disease.

    Science.gov (United States)

    Lutsenko, Svetlana

    2008-12-01

    Wilson's disease is a severe human disorder of copper homoeostasis. The disease is associated with various mutations in the ATP7B gene that encodes a copper-transporting ATPase, and a massive accumulation of copper in the liver and several other tissues. The most frequent disease manifestations include a wide spectrum of liver pathologies as well as neurological and psychiatric abnormalities. A combination of copper chelators and zinc therapy has been used to prevent disease progression; however, accurate and timely diagnosis of the disease remains challenging. Similarly, side effects of treatments are common. To understand better the biochemical and cellular basis of Wilson's disease, several animal models have been developed. This review focuses on genetically engineered Atp7b(-/-) mice and describes the properties of these knockout animals, insights into the disease progression generated using Atp7b(-/-) mice, as well as advantages and limitations of Atp7b(-/-) mice as an experimental model for Wilson's disease.

  10. Direct determination of Wilson coefficients using B 0 → K ∗0 μ + μ - decays

    Science.gov (United States)

    Hurth, T.; Langenbruch, C.; Mahmoudi, F.

    2017-11-01

    A method to directly determine the Wilson coefficients for rare b → s transitions using B 0 → K ∗0 μ + μ - decays in an unbinned maximum likelihood fit is presented. The method has several advantages compared to the conventional determination of the Wilson coefficients from angular observables that are determined in bins of q 2, the square of the mass of the dimuon system. The method uses all experimental information in a more efficient way and automatically accounts for experimental correlations. Performing pseudoexperiments, we show the improved sensitivity of the proposed method for the Wilson coefficients. We also demonstrate that it will be possible to use the method with the combined Run 1 and 2 data sample taken by the LHCb experiment.

  11. Identification of two novel mutations in the ATP7B gene that cause Wilson's disease

    Institute of Scientific and Technical Information of China (English)

    Hong-Wen Zhu; Yu-Min Li; Zhong-Bin Tao; Gang Su; Qiao-Ying Jin; Liang-Tao Zhao; Jia-Rui Zhu; Jun Yan; Tian-Yu Yu; Jie-Xian Ding

    2017-01-01

    Background:Wilson's disease is an autosomal recessive disorder characterized by liver disease and/or neurologic deficits due to copper accumulation and is caused by pathogenic mutations in the ATP7B gene.Methods:Two unrelated Chinese patients born to nonconsanguineous parents who were diagnosed with earlyonset Wiison's disease.DNA sequencing and bioinformation analysis were conducted.Results:We have identified four mutations in two family trios,of which two were novel,namely,c.3028A>G(p.K1010E) and c3992T>G (p.Y1331X),in each patient.Conclusions:Gene testing is playing an important role in diagnosis of Wilson's disease.The early-onset of Wilson's disease is apparently not associated with P-ATPase domain in the ATP7B protein.Our findings further widen the spectrum of mutations involving the ATP7B gene.

  12. Use of zinc-copper metabolic interactions in the treatment of Wilson's disease.

    Science.gov (United States)

    Brewer, G J; Yuzbasiyan-Gurkan, V; Lee, D Y

    1990-10-01

    Zinc acetate is becoming a well-established therapy for the treatment of Wilson's disease. It is excellent for maintenance therapy and for the treatment of the presymptomatic patient. Current evidence suggests that it will also be excellent for the treatment of the pregnant patient. Zinc acts by inducing intestinal cell metallothionein, which binds copper with high affinity, blocking its absorption, and causing its excretion in the stool. We have shown that zinc, even in doses as low as 25 mg daily, negatively affects copper balance. Zinc in doses of 50 mg three times daily, with all doses separated from food, controls the abnormal positive copper balance, blocks uptake of orally administered 64Cu, controls urine and plasma copper, prevents the reaccumulation of hepatic copper, and prevents the development or progression of symptoms of copper toxicosis in Wilson's disease patients. Zinc acetate will probably be licensed in the near future for the treatment of Wilson's disease. We recommend that physicians use urine and plasma copper, and urine zinc, as primary monitoring tools. In contrast to the comfortable situation with maintenance therapy, the initial treatment of acutely ill Wilson's disease patients is not well worked out. Patients with neurological disease often get worse initially on penicillamine, and zinc acts more slowly than is ideal. We have initiated studies of tetrathiomolybdate for this purpose. Studies of biliary secretions of normal subjects suggest that they excrete regulatory (excess) copper packaged in a protease-resistant ceruloplasmin fragment. This fragment is missing in Wilson's disease bile. The gene for Wilson's disease is on chromosome 13, close to the retinoblastoma locus.(ABSTRACT TRUNCATED AT 250 WORDS)

  13. The Clinical Manifestations, Treatment Efficacy and Adverse Drug Reactions in 62 Iranian Child with Wilson Disease

    Directory of Open Access Journals (Sweden)

    Mehri Najafi

    2014-09-01

    Full Text Available Introduction: The Wilson disease is an autosomal recessive disease in which the liver, central nervous system, eyes, blood and other parts of the body involved. Timely diagnosis and appropriate treatment of the disease requires awareness of the clinical presentations of this disease in children.Methods: This case series study included 62 patients with Wilson disease who admitted to children's Medical Center in the years 2012-2003.Results: 56% of patients were male. The average age of diagnosis was 9.73 years old (5-17 years and this was higher in patients with early neurologic symptoms (P = 0.85.( 64.5% of the patients had the hepatic symptoms at the time of diagnosis and the most common type of hepatic involvement was cirrhosis (39.3% and hepatitis (17.5% respectively. 17.7% of the patients also had early neurological symptoms. A positive family history for the Wilson Disease were found in 27.4% of patients. 74.2% of patients had KF ring and the frequency of these symptom was higher in patients with early neurological involvement. 83.9% of patients were treated successfully with D-penicillamine and In 30% of patients, adverse drug reactions were seen.Conclusion: Children with unknown liver disease should be evaluated for Wilson disease and the first-degree relatives of patients should be screened. . D-penicillamine have important side effects, but due to the low cost and the availability is an appropriate drug to treat the Wilson disease..Key words: Wilson Disease, Hepatic Involvement, Neurologic Involvement , KF ring ,D-Penicillamine.

  14. Modeling of the time sharing for lecturers

    Directory of Open Access Journals (Sweden)

    E. Yu. Shakhova

    2017-01-01

    Full Text Available In the context of modernization of the Russian system of higher education, it is necessary to analyze the working time of the university lecturers, taking into account both basic job functions as the university lecturer, and others.The mathematical problem is presented for the optimal working time planning for the university lecturers. The review of the documents, native and foreign works on the study is made. Simulation conditions, based on analysis of the subject area, are defined. Models of optimal working time sharing of the university lecturers («the second half of the day» are developed and implemented in the system MathCAD. Optimal solutions have been obtained.Three problems have been solved:1 to find the optimal time sharing for «the second half of the day» in a certain position of the university lecturer;2 to find the optimal time sharing for «the second half of the day» for all positions of the university lecturers in view of the established model of the academic load differentiation;3 to find the volume value of the non-standardized part of time work in the department for the academic year, taking into account: the established model of an academic load differentiation, distribution of the Faculty number for the positions and the optimal time sharing «the second half of the day» for the university lecturers of the department.Examples are given of the analysis results. The practical application of the research: the developed models can be used when planning the working time of an individual professor in the preparation of the work plan of the university department for the academic year, as well as to conduct a comprehensive analysis of the administrative decisions in the development of local university regulations.

  15. La Enfermedad de Wilson (Primer Caso Costarricense de Enferemedad de Wilson Diagnosticado en Vida Mediante Localización de la Ceruloplasma en el Electroferograma Serico

    OpenAIRE

    Esquivel Herrera, Enrique; Jiménez Porras, Jesús M.; González Leiva, Marco Antonio; Rojas Solano, Luis F.

    2015-01-01

    El neurólogo inglés Kinnier Wilson describió, en 1912, un nuevo síndrome de tipo familiar, caracterizado por degeneración bilateral del núcleo lenticular del cerebro y cirrosis hepática, por lo que a esta entidad nosológica se le denomina hoy en día enfermedad de Wilson o degeneración hepatoZenticular (1 , 2, 3, 4).Es una enfermedad rara, pero no excepcional, que tiene las siguientes manifestaciones clínicas: cirrosis hepática tipo postnecrótico, con daño progresivo del sistema nervioso, que ...

  16. Characteristics of good mathematics lecturers based on students and lecturers perspectives

    Science.gov (United States)

    Hapsari, Trusti; Putri, Dian Permana; Raharjo, Jajo Firman

    2017-05-01

    This study aims to determine the characteristics of good mathematics lecturers based on students' and lecturers' perspectivesand compare the characteristics of good lecturers/ teachers which are in accordance with the findings of some previous studies and the theories. This study is survey study. The Data were collected through questionnaires and interview. The population consists of some mathematics students from the first level through the third level and some mathematics education lecturers of a private university in West Java. Qualitative analysis was undertaken to examine the results of questionnaires and interviews. The finding shows that the characteristic of good mathematics lecturers is inspiring. They can inspire other mathematics lecturers and educators in general. Based on the students and lecturers' perspective, some characteristics of good mathematics lecturers are mastering the materials well, being on time, being objective, understanding the students, presenting the materials with clearly, and being disciplined. Some other characteristic mentioned are: teaching eagerly, being unhurried, being friendly, giving exemplary and preparing the lesson well. These characteristics are not much different from the characteristics described by some previous researchers and some theories of experts, i.e. mastering the subject matters well, pedagogic, and work wholeheartedly.

  17. Reaction Lecture : Text Messaging to Increase Student Engagement in Large-Scale Lectures

    NARCIS (Netherlands)

    Winnips, Koos; Heutink, Joost; Beldhuis, Hans; Greener, S; Rospigliosi, A

    2011-01-01

    By helping to be active during large scale lectures, students remember better what is presented, and can better connect new knowledge to entry knowledge. In large scale lectures with more than 150 students, it is nearly impossible to manage personal, face-to-face discussions and interaction. Based

  18. The Transuranium Elements: Early History (Nobel Lecture)

    Science.gov (United States)

    McMillan, E. M.

    1951-12-12

    In this talk the author tells of the circumstances that led to the discovery of neptunium, the first element beyond uranium, and the partial identification of plutonium, the next one beyond that. The part of the story that lies before 1939 has already been recounted here in the Nobel lectures of Fermi and Hahn. Rather the author starts with the discovery of fission by Hahn and Strassmann. News of this momentous discovery reached Berkeley early in 1939. The staff of the Radiation Laboratory was put into a state of great excitement and several experiments of a nature designed to check and extend the announced results were started, using ionization chambers and pulse amplifiers, cloud chambers, chemical methods, and so forth. The author decided to do an experiment of a very simple kind. When a nucleus of uranium absorbs a neutron and fission takes place, the two resulting fragments fly apart with great violence, sufficient to propel them through air or other matter for some distance. This distance, called the "range", is quantity of some interest, and the author undertook to measure it by observing the depth of penetration of the fission fragments in a stack of thin aluminum foils. The fission fragments came from a thin layer of uranium oxide spread on a sheet of paper, and exposed to neutrons from a beryllium target bombarded by 8 Mev deuterons in the 37-inch cyclotron. The aluminum foils, each with a thickness of about half a milligram per square centimeter, were stacked like the pages of a book in immediate contact with the layer of uranium oxide. After exposure to the neutrons, the sheets of aluminum were separated and examined for radioactivity by means of an ionization chamber. The fission fragments of course are radioactive atoms, and their activity is found where they stop.

  19. Viscosity modeling for ionic liquid solutions by Eyring-Wilson equation

    Directory of Open Access Journals (Sweden)

    He Yang-Chun

    2012-01-01

    Full Text Available A semi-theoretical model based on the classical Eyring’s mixture viscosity equation and the Wilson activity coefficient equation is presented for correlating the viscosity of ionic liquids with solvent systems. The accuracy of the proposed model was verified by comparing calculated and experimental viscosity values from literatures for 49mixtures with total 1560 data points. The results show that the equation similar to the Wilson activity coefficient equation can be well applied to describe the non-ideal term in the Eyring’s mixture viscosity equation. The model has a relatively simple mathematical form and can be easily incorporated into process simulation software.

  20. Vision to Reality: From Robert R. Wilson's Frontier to Leon M. Lederman's Fermilab

    Science.gov (United States)

    Hoddeson, Lilian; Kolb, Adrienne

    We examine the roles of vision and leadership in creating and directing Fermi National Accelerator Laboratory from the late 1960s through the 1980s. The story divides into two administrations having different problems and accomplishments, that of Robert R. Wilson from 1967-1978, which saw the transformation from cornfield to frontier physics facility, and that of Leon M. Lederman from 1979-1989, in which the laboratory evolved into one of the world's major high-energy facilities. Lederman's pragmatic vision of a user-based experimental community helped him to convert the pioneering facility that Wilson had built frugally into a laboratory with a stable scientific, cultural, and funding environment.

  1. La maladie de Wilson chez l'enfant: à propos de 20 cas | Idrissi | Pan ...

    African Journals Online (AJOL)

    La maladie de Wilson ou dégénérescence hépato-lenticulaire est une affection génétique autosomique récessive caractérisée par une accumulation toxique de ... Nous avons réalisé une étude rétrospective portant sur 20 cas de maladie de Wilson colligés au sein du service de pédiatrie du CHU HASSAN II de Fès sur une ...

  2. Wilson's disease: a new gene and an animal model for an old disease.

    Science.gov (United States)

    Cuthbert, J A

    1995-08-01

    Wilson's disease is an autosomal recessive, inherited disorder of copper metabolism. In normal individuals, copper homeostasis is controlled by the balance between intestinal absorption of dietary copper and hepatic excretion of excess copper in bile. In Wilson's disease, hepatic copper is neither excreted in bile nor incorporated into ceruloplasmin and copper accumulates to toxic levels. The Wilson's disease gene (WND) encodes a putative copper-transporting protein that is expressed almost exclusively in the liver. The predicted structure of the protein product is that of a P-type ATPase with striking homology to bacterial copper transporters and the gene product of another inherited disorder of copper metabolism, Menkes' disease. A rat model of Wilson's disease has recently been identified. The Long-Evans Cinnamon (LEC) rat manifests elevated hepatic copper, defective incorporation of copper into ceruloplasmin, and reduced biliary excretion of copper. The rat homologue of the WND is abnormal in LEC rats. Clinical manifestations of Wilson's disease arise directly from copper-induced damage to hepatocytes (hepatic presentation) or indirectly after the release of copper from the liver with subsequent damage to the brain (neuropsychiatric presentation) and other organs. Genetic heterogeneity (different mutations in a single gene) may account for some of the variability in Wilsonian presentations. The diagnosis of Wilson's disease depends on the demonstration of disordered copper metabolism, manifested as elevated urinary and hepatic copper and low ceruloplasmin levels. However, none of the abnormal findings in Wilson's disease is pathognomonic. Genetic diagnosis, in the absence of family studies, is likely to be difficult since many different mutations result in the disease. Management of Wilson's disease involves decreasing excess levels of copper accumulated in the liver, brain, and other organs. Copper chelation therapy, to increase urinary excretion of copper, is

  3. Making Moral Judgments from a World-Historic Standpoint: The Case of Woodrow Wilson.

    Science.gov (United States)

    Fuller, Steve

    This comment reflects on the recent row over Woodrow Wilson's legacy, which has focussed on his undeniable racism. This was in pursuit of a 'Progressive' agenda which paved the way for the United States to become the geopolitical force that it continues to be today. Without necessarily approving of Wilson's particular judgements, I argue that he operated with a 'world-historic' sense of morality characteristic of Realpolitik , a perspective which might be worth considering by those who believe that modern preoccupations with 'race', 'class' and 'gender' will remain part of the sociological firmament indefinitely.ᅟ.

  4. Parton densities in quantum chromodynamics. Gauge invariance, path-dependence, and Wilson lines

    Energy Technology Data Exchange (ETDEWEB)

    Cherednikov, Igor O. [Antwerpen Univ. (Belgium). Dept. Fysica; Veken, Frederik F. van der [CERN, Geneva (Switzerland)

    2017-05-01

    The purpose of this book is to give a systematic pedagogical exposition of the quantitative analysis of Wilson lines and gauge-invariant correlation functions in quantum chromodynamics. Using techniques from the previous volume (Wilson Lines in Quantum Field Theory, 2014), an ab initio methodology is developed and practical tools for its implementation are presented. Emphasis is put on the implications of gauge invariance and path-dependence properties of transverse-momentum dependent parton density functions. The latter are associated with the QCD factorization approach to semi-inclusive hadronic processes, studied at currently operating and planned experimental facilities.

  5. Spitzer observations of the asteroid-comet transition object and potential spacecraft target 107P (4015) Wilson-Harrington

    Science.gov (United States)

    Licandro, J.; Campins, H.; Kelley, M.; Fernández, Y.; Delbó, M.; Reach, W. T.; Groussin, O.; Lamy, P. L.; Toth, I.; A'Hearn, M. F.; Bauer, J. M.; Lowry, S. C.; Fitzsimmons, A.; Lisse, C. M.; Meech, K. J.; Pittichová, J.; Snodgrass, C.; Weaver, H. A.

    2009-12-01

    Context: Near-Earth asteroid-comet transition object 107P/ (4015) Wilson-Harrington is a possible target of the joint European Space Agency (ESA) and Japanese Aerospace Exploration Agency (JAXA) Marco Polo sample return mission. Physical studies of this object are relevant to this mission, and also to understanding its asteroidal or cometary nature. Aims: Our aim is to obtain significant new constraints on the surface thermal properties of this object. Methods: We present mid-infrared photometry in two filters (16 and 22 μm) obtained with NASA's Spitzer Space Telescope on February 12, 2007, and results from the application of the Near Earth Asteroid Thermal Model (NEATM). We obtained high S/N in two mid-IR bands allowing accurate measurements of its thermal emission. Results: We obtain a well constrained beaming parameter (η = 1.39±0.26) and obtain a diameter and geometric albedo of D = 3.46±0.32 km, and pV = 0.059±0.011. We also obtain similar results when we apply this best-fitting thermal model to single-band mid-IR photometry reported by Campins et al. (1995, P&SS, 43, 733), Kraemer et al. (2005, AJ, 130, 2363) and Reach et al. (2007, Icarus, 191, 298). Conclusions: The albedo of 4015 Wilson-Harrington is low, consistent with those of comet nuclei and primitive C-, P-, D-type asteorids. We establish a rough lower limit for the thermal inertia of W-H of 60 Jm-2s-0.5 K-1 when it is at r = 1 AU, which is slightly over the limit of 30 Jm-2 s-0.5 K-1 derived by Groussin et al. (2009, Icarus, 199, 568) for the thermal inertia of the nucleus of comet 22P/Kopff.

  6. The Web-Lecture - a viable alternative to the traditional lecture format?

    Science.gov (United States)

    Meibom, S.

    2004-12-01

    Educational research shows that students learn best in an environment with emphasis on teamwork, problem-solving, and hands-on experience. Still professors spend the majority of their time with students in the traditional lecture-hall setting where the combination of large classes and limited time prevents sufficient student-teacher interaction to foster an active learning environment. Can modern computer technology be used to provide "lecture-type" information to students via the World Wide Web? If so, will that help professors make better and/or different use of their scheduled time with the students? Answering these questions was the main motivation for the Extra-Solar Planet Project. The Extra-Solar Planet Project was designed to test the effectiveness of a lecture available to the student on the World Wide Web (Web-Lecture) and to engage the students in an active learning environment were their use the information presented in the Web-Lecture. The topic of the Web-Lecture was detection of extra-solar planets and the project was implemented into an introductory astronomy course at University of Wisconsin Madison in the spring of 2004. The Web-Lecture was designed to give an interactive presentation of synchronized video, audio and lecture notes. It was created using the eTEACH software developed at the University of Wisconsin Madison School of Engineering. In my talk, I will describe the project, show excerpts of the Web-Lecture, and present assessments of student learning and results of student evaluations of the web-lecture format.

  7. Vocal intensity in lecturers: Results of measurements conducted during lecture sessions

    Directory of Open Access Journals (Sweden)

    Witold Mikulski

    2013-12-01

    Full Text Available Background: Occupational voice users (inter alia: lecturers speak with different levels of vocal intensity. Speakers adjust this intensity knowingly (e.g. to underline the importance of fragments of the speech or unknowingly. The unknown adjustment of voice intensity occurs e.g. in the presence of high acoustic background noise (so-called Lombard effect, but it also results from many other factors: hearing loss, construction of the vocal tract, habits and others. The aim of the article is to confirm the thesis that in similar conditions of acoustic properties of the room different lecturers speak with different levels of vocal intensity. Materials and Methods: The study was conducted in a group of 10 lecturers in the same conference room. A-weighted sound pressure level determined at 1 m from the lecturer's mouth was adopted as a parameter defining the intensity of the lecturer's voice. The levels of all lecturers' voice intensity were compared and evaluated according to the criteria defined in EN ISO 9921. Results: Nine in ten lecturers were speaking with normal voice intensity (60-65 dB and only one full-time university lecturer was speaking with raised voice (66-71 dB. Conclusions: It was found that in the room of the same acoustic conditions the lecturers spoke with different intensities of voice. Some lecturers occasionally, and one all the time spoke with the voice intensity specified by PN-EN ISO 9921 as a raised voice. The results of the preliminary study warrant further studies in a larger group of teachers. Med Pr 2013;64(6:797–804

  8. Interactive lectures: Clickers or personal devices?

    Science.gov (United States)

    Morrell, Lesley J; Joyce, Domino A

    2015-01-01

    Audience response systems ('clickers') are frequently used to promote participation in large lecture classes, and evidence suggests that they convey a number of benefits to students, including improved academic performance and student satisfaction. The limitations of these systems (such as limited access and cost) can be overcome using students' personal electronic devices, such as mobile phones, tablets and laptops together with text message, web- or app-based polling systems. Using questionnaires, we compare student perceptions of clicker and smartphone based polling systems. We find that students prefer interactive lectures generally, but those that used their own device preferred those lectures over lectures using clickers. However, device users were more likely to report using their devices for other purposes (checking email, social media etc.) when they were available to answer polling questions. These students did not feel that this distracted them from the lecture, instead, concerns over the use of smartphones centred around increased battery usage and inclusivity for students without access to suitable technology. Our results suggest that students generally preferred to use their own devices over clickers, and that this may be a sensible way to overcome some of the limitations associated with clickers, although issues surrounding levels of distraction and the implications for retention and recall of information need further investigation.

  9. Interactive lectures: Clickers or personal devices?

    Science.gov (United States)

    Morrell, Lesley J.; Joyce, Domino A.

    2015-01-01

    Audience response systems (‘clickers’) are frequently used to promote participation in large lecture classes, and evidence suggests that they convey a number of benefits to students, including improved academic performance and student satisfaction. The limitations of these systems (such as limited access and cost) can be overcome using students’ personal electronic devices, such as mobile phones, tablets and laptops together with text message, web- or app-based polling systems. Using questionnaires, we compare student perceptions of clicker and smartphone based polling systems. We find that students prefer interactive lectures generally, but those that used their own device preferred those lectures over lectures using clickers. However, device users were more likely to report using their devices for other purposes (checking email, social media etc.) when they were available to answer polling questions. These students did not feel that this distracted them from the lecture, instead, concerns over the use of smartphones centred around increased battery usage and inclusivity for students without access to suitable technology. Our results suggest that students generally preferred to use their own devices over clickers, and that this may be a sensible way to overcome some of the limitations associated with clickers, although issues surrounding levels of distraction and the implications for retention and recall of information need further investigation. PMID:26594327

  10. 76 FR 30963 - Notice of Intent To Prepare an Environmental Impact Statement for the Proposed Wilson Creek Wind...

    Science.gov (United States)

    2011-05-27

    ... would be considered for development if the wind resource in the Atlanta Summit and White Rock areas is... Wilson Creek Wind Project, Lincoln County, NV AGENCY: Bureau of Land Management, Interior. ACTION: Notice... right-of-way (ROW) application submitted by Wilson Creek Power Partners, LLC, for a wind energy...

  11. 78 FR 51735 - Notice of FY 2013 Refugee Social Services Formula Awards to States and Wilson/Fish Alternative...

    Science.gov (United States)

    2013-08-21

    ... to States and Wilson/Fish Alternative Project Grantees AGENCY: Office of Refugee Resettlement, ACF... and Wilson/Fish Alternative Project grantees. The FY 2013 formula allocations for Social Services are.../fdsys/pkg/FR-2013-06-28/pdf/2013-15465.pdf . Statutory Authority: Sections 412(c)(1)(B) of the...

  12. 78 FR 51736 - Notice of FY 2013 Refugee Targeted Assistance Formula Awards to States and Wilson/Fish...

    Science.gov (United States)

    2013-08-21

    ... Awards to States and Wilson/Fish Alternative Project Grantees AGENCY: Office of Refugee Resettlement, ACF... States and Wilson/Fish Alternative Project grantees. DATES: The awards are effective immediately. FOR... at http://www.gpo.gov/fdsys/pkg/FR-2013-06-28/pdf/2013-15465.pdf . Statutory Authority: Section 412(c...

  13. Explicit constructivism: a missing link in ineffective lectures?

    Science.gov (United States)

    Prakash, E S

    2010-06-01

    This study tested the possibility that interactive lectures explicitly based on activating learners' prior knowledge and driven by a series of logical questions might enhance the effectiveness of lectures. A class of 54 students doing the respiratory system course in the second year of the Bachelor of Medicine and Bachelor of Surgery program in my university was randomized to two groups to receive one of two types of lectures, "typical" lectures (n = 28, 18 women and 10 men) or "constructivist" lectures (n = 26, 19 women and 7 men), on the same topic: the regulation of respiration. Student pretest scores in the two groups were comparable (P > 0.1). Students that received the constructivist lectures did much better in the posttest conducted immediately after the lectures (6.8 +/- 3.4 for constructivist lectures vs. 4.2 +/- 2.3 for typical lectures, means +/- SD, P = 0.004). Although both types of lectures were well received, students that received the constructivist lectures appeared to have been more satisfied with their learning experience. However, on a posttest conducted 4 mo later, scores obtained by students in the two groups were not any different (6.9 +/- 3 for constructivist lectures vs. 6.9 +/- 3.7 for typical lectures, P = 0.94). This study adds to the increasing body of evidence that there is a case for the use of interactive lectures that make the construction of knowledge and understanding explicit, easy, and enjoyable to learners.

  14. Lecture 4: April 11, 1927

    Science.gov (United States)

    Montessori, Maria

    2016-01-01

    Using examples from the animal world, Montessori speaks of the natural laws of life and the phases of childhood that are different than that of the adult. The child develops independently of the adult. Montessori says, "The child is the period when man is created," and "The child is a worker." Through work, the child can arrive…

  15. Mathematical omnibus thirty lectures on classic mathematics

    CERN Document Server

    Fuchs, Dmitry; Fuchs, Dmitry

    2007-01-01

    The book consists of thirty lectures on diverse topics, covering much of the mathematical landscape rather than focusing on one area. The reader will learn numerous results that often belong to neither the standard undergraduate nor graduate curriculum and will discover connections between classical and contemporary ideas in algebra, combinatorics, geometry, and topology. The reader's effort will be rewarded in seeing the harmony of each subject. The common thread in the selected subjects is their illustration of the unity and beauty of mathematics. Most lectures contain exercises, and solutions or answers are given to selected exercises. A special feature of the book is an abundance of drawings (more than four hundred), artwork by an accomplished artist, and about a hundred portraits of mathematicians. Almost every lecture contains surprises for even the seasoned researcher.

  16. Professional development of international classroom lecturers

    DEFF Research Database (Denmark)

    Lauridsen, Karen M.

    With a rapidly growing number of students learning and lecturers teaching through a language other than their own first language, there is equally a growing need to consider how lecturers are trained to teach in the international classroom where students have a range of different linguistic...... they provide professional development programmes for the teachers of their international study programmes. Only a small part of them did, and the majority of the programmes were optional. At the same time many lecturers are uncertain as to how they could or should deal with the challenges of the multilingual...... and weaknesses) and discuss their applicability in a wider context. Key words: Professional development; International classroom; English Medium Instruction, Opportunities and challenges Simon, Eszter & Gabriela Pleschová (eds).2013. Teacher Development in Higher Education. Existing Programs, Program Impact...

  17. Optoelectronic lessons as an interdisciplinary lecture

    Science.gov (United States)

    Wu, Dan; Wu, Maocheng; Gu, Jihua

    2017-08-01

    It is noticed that more and more students in college are passionately curious about the optoelectronic technology, since optoelectronic technology has advanced extremely quickly during the last five years and its applications could be found in a lot of domains. The students who are interested in this area may have different educational backgrounds and their majors cover science, engineering, literature and social science, etc. Our course "History of the Optoelectronic Technology" is set up as an interdisciplinary lecture of the "liberal education" at our university, and is available for all students with different academic backgrounds from any departments of our university. The main purpose of the course is to show the interesting and colorful historical aspects of the development of this technology, so that the students from different departments could absorb the academic nourishment they wanted. There are little complex derivations of physical formulas through the whole lecture, but there are still some difficulties about the lecture which is discussed in this paper.

  18. Lectures on formal and rigid geometry

    CERN Document Server

    Bosch, Siegfried

    2014-01-01

    A first version of this work appeared in 2005 as a Preprint of the Collaborative Research Center "Geometrical Structures in Mathematics" at the University of Münster. Its aim was to offer a concise and self-contained 'lecture-style' introduction to the theory of classical rigid geometry established by John Tate, together with the formal algebraic geometry approach launched by Michel Raynaud. These Lectures are now viewed commonly as an ideal means of learning advanced rigid geometry, regardless of the reader's level of background. Despite its parsimonious style, the presentation illustrates a number of key facts even more extensively than any other previous work. This Lecture Notes Volume is a revised and slightly expanded version of the original preprint and has been published at the suggestion of several experts in the field.

  19. Lectures in the history of mathematics

    CERN Document Server

    Bos, Henk J M

    1993-01-01

    "[These lectures] are about themes of the history of mathematics which, for various reasons, are dear to me. The early differential and integral calculus, the work of Christiaan Huygens, and the concept of construction in seventeenth- and eighteenth-century mathematics are the three themes around which much of my research has concentrated and which continue to fascinate me by the insights they offer in the development of that special human activity called mathematics." -from the Introduction This volume contains eleven lectures ranging over a variety of topics in the history of mathematics. The lectures, presented between 1970 and 1987, were delivered in a variety of venues and appeared only in less accessible publications. Those who teach mathematics, as well as mathematics historians, will appreciate this insightful, wide-ranging book.

  20. Darwin's Revolution in Thought: An Illustrated Lecture. Teaching Guide and Videotape.

    Science.gov (United States)

    Gould, Stephen Jay

    "Darwin's Revolution in Thought" is Stephen Jay Gould's definitive treatise on Charles Darwin. This 50-minute classroom edition videotaped lecture is structured in the form of a paradox and three riddles about Darwin's life. Each is designed to shed light on one of the key features of the theory of natural selection, its philosophical…

  1. Centuries of Change: Movement's Many Faces. The Thirtieth Amy Morris Homans Lecture.

    Science.gov (United States)

    Paul, Joan

    1996-01-01

    This Amy Morris Homans Lecture illustrates and interprets the philosophical meanings behind changing movement patterns in the field of physical education, examining the foreign gymnastic or formal era (1820s to the early 20th century), the natural movement era (1900 through the 1930s), and the present period of change, also called the discipline…

  2. On performing concepts during science lectures

    Science.gov (United States)

    Pozzer-Ardenghi, Lilian; Roth, Wolff-Michael

    2007-01-01

    When lecturing, teachers make use of both verbal and nonverbal communication. What is called teaching, therefore, involves not only the words and sentences a teacher utters and writes on the board during a lesson, but also all the hands/arms gestures, body movements, and facial expressions a teacher performs in the classroom. All of these communicative modalities constitute resources that are made available to students for making sense of and learning from lectures. Yet in the literature on teaching science, these other means of communication are little investigated and understood - and, correspondingly, they are undertheorized. The purpose of this position paper is to argue for a different view of concepts in lectures: they are performed simultaneously drawing on and producing multiple resources that are different expressions of the same holistic meaning unit. To support our point, we provide examples from a database of 26 lectures in a 12th-grade biology class, where the human body was the main topic of study. We analyze how different types of resources - including verbal and nonverbal discourse and various material artifacts - interact during lectures. We provide evidence for the unified production of these various sense-making resources during teaching to constitute a meaning unit, and we emphasize particularly the use of gestures and body orientations inside this meaning unit. We suggest that proper analyses of meaning units need to take into account not only language and diagrams but also a lecturer's pointing and depicting gestures, body positions, and the relationships between these different modalities. Scientific knowledge (conceptions) exists in the concurrent display of all sense-making resources, which we, following Vygotsky, understand as forming a unit (identity) of nonidentical entities.

  3. Algorithms and Data Structures (lecture 1)

    CERN Multimedia

    CERN. Geneva

    2018-01-01

    Algorithms have existed, in one form or another, for as long as humanity has. During the second half of the 20th century, the field was revolutionised with the introduction of ever faster computers. In these lectures we discuss how algorithms are designed, how to evaluate their speed, and how to identify areas of improvement in existing algorithms. An algorithm consists of more than just a series of instructions; almost as important is the memory structure of the data on which it operates. A part of the lectures will be dedicated to a discussion of the various ways one can store data in memory, and their advantages and disadvantages.

  4. The McAndrews Leadership Lecture: Origins.

    Science.gov (United States)

    Hamm, Anthony W; Burkhart, Lori A

    2015-12-01

    This article describes the origins and rationale for the McAndrews Leadership Lecture and explains why the American Chiropractic Association honors George and Jerome McAndrews. George and Jerome McAndrews' backgrounds demonstrate their leadership contributions to the chiropractic profession. Jerome McAndrews, a chiropractor, held substantial leadership roles in the chiropractic profession. George McAndrews, a lawyer, administered a permanent injunction forbidding the American Medical Association's restraint of trade toward the chiropractic profession. The American Chiropractic Association has established the McAndrews Leadership Lecture to honor their contributions to the chiropractic profession.

  5. Wilson Disease Protein ATP7B Utilizes Lysosomal Exocytosis to Maintain Copper Homeostasis

    NARCIS (Netherlands)

    Polishchuk, Elena V.; Concilli, Mafalda; Iacobacci, Simona; Chesi, Giancarlo; Pastore, Nunzia; Piccolo, Pasquale; Paladino, Simona; Baldantoni, Daniela; van IJzendoorn, Sven C. D.; Chan, Jefferson; Chang, Christopher J.; Amoresano, Angela; Pane, Francesca; Pucci, Piero; Tarallo, Antonietta; Parenti, Giancarlo; Brunetti-Pierri, Nicola; Settembre, Carmine; Ballabio, Andrea; Polishchuk, Roman S.

    2014-01-01

    Copper is an essential yet toxic metal and its overload causes Wilson disease, a disorder due to mutations in copper transporter ATP7B. To remove excess copper into the bile, ATP7B traffics toward canalicular area of hepatocytes. However, the trafficking mechanisms of ATP7B remain elusive. Here, we

  6. The treatment of Wilson's disease, a rare genetic disorder of copper metabolism.

    Science.gov (United States)

    Purchase, Rupert

    2013-01-01

    Wilson's disease is a rare autosomal recessive disease characterised by the deposition of copper in the brain, liver; cornea, and other organs. The overload of copper inevitably leads to progressive liver and neurological dysfunction. Copper overload in patients with Wilson's disease is caused by impairment to the biliary route for excretion of dietary copper A combination of neurological, psychiatric and hepatic symptoms can make the diagnosis of Wilson's disease challenging. Most symptoms appear in the second and third decades of life. The disease affects between one in 30,000 and one in 100,000 individuals, and is fatal if left untreated. Five drugs are currently available to treat Wilson's disease: British Anti-Lewisite; D-penicillamine; trientine; zinc sulfate or acetate; and ammonium tetrathiomolybdate. Each drug can reduce copper levels and/or transform copper into a metabolically inert and unavailable form in the patient. The discovery and introduction of these five drugs owes more to the inspiration of a few dedicated physicians and agricultural scientists than to the resources of the pharmaceutical industry.

  7. Recent results on the 3-loop heavy flavor Wilson coefficients in deep-inelastic scattering

    Energy Technology Data Exchange (ETDEWEB)

    Bluemlein, J.; Freitas A. de; Raab, C.; Wissbrock, F. [Deutsches Elektronen-Synchrotron (DESY), Zeuthen (Germany); Ablinger, J.; Hasselhuhn, A.; Round, M.; Schneider, C. [Johannes Kepler Univ., Linz (Austria). Research Inst. for Symbolic Computation; Manteuffel, A. von [Mainz Univ. (Germany). PRISMA Cluster of Excellence; Mainz Univ. (Germany). Inst. fuer Physik

    2013-07-15

    We report on recent progress in the calculation of the 3-loop massive Wilson coefficients in deep-inelastic scattering at general values of N for neutral and charged current reactions in the asymptotic region Q{sup 2}>>m{sup 2}.

  8. Face of the giant panda sign in Wilson disease | Chakraborty | SA ...

    African Journals Online (AJOL)

    Wilson disease usually presents with neurological or hepatic manifestations. Magnetic resonance imaging (MRI) of the brain is most informative in diagnosing this disease, especially in patients with neurological features. High T2 signal intensity in the corpus striatum is the most commonly encountered MRI finding. The 'face ...

  9. Converting the H. W. Wilson Company Indexes to an Automated System: A Functional Analysis.

    Science.gov (United States)

    Regazzi, John J.

    1984-01-01

    Description of the computerized information system that supports the editorial and manufacturing processes involved in creation of Wilson's subject indexes and catalogs includes the major subsystems--online data entry, batch input processing, validation and release, file generation and database management, online and offline retrieval, publication…

  10. An anisotropic preconditioning for the Wilson fermion matrix on the lattice

    Energy Technology Data Exchange (ETDEWEB)

    Balint Joo, Robert G. Edwards, Michael J. Peardon

    2010-01-01

    A preconditioning for the Wilson fermion matrix on the lattice is defined which is particularly suited to the case when the temporal lattice spacing is much smaller than the spatial one. Details on the implementation of the scheme are given. The method is tested in numerical studies of QCD on anisotropic lattices.

  11. Spatial Wilson loops in the classical field of high-energy heavy-ion collisions

    NARCIS (Netherlands)

    Petreska, Elena

    2014-01-01

    It has been previously shown numerically that the expectation value of the magnetic Wilson loop at the initial time of a heavy-ion collision exhibits area law scaling. This was obtained for a classical non-Abelian gauge field in the forward light cone and for loops of area $A\\gtrsim 2/Q_s^2$. Here,

  12. Wilson cycle passive margins: Control of orogenic inheritance on continental breakup

    DEFF Research Database (Denmark)

    Petersen, Kenni D.; Schiffer, Christian

    2016-01-01

    Abstract Rifts and passive margins often develop along old suture zones where colliding continents merged during earlier phases of the Wilson cycle. For example, the North Atlantic formed after continental break-up along sutures formed during the Caledonian and Variscan orogenies. Even though suc...... as igneous bodies. The latter is consistent with dipping sub-Moho reflectors often observed in passive margins....

  13. Inside the Sex Ed Studio: An Interview with Susan N. Wilson

    Science.gov (United States)

    Taverner, William J.

    2007-01-01

    "Inside the Sex Ed Studio" profiles leaders in the field of sexuality education. Susan N. Wilson, former Executive Coordinator of the Network for Family Life Education, long-time advocate for sexuality education, and the driving force behind New Jersey's K-12 mandate for comprehensive sexuality education was the first such leader to be…

  14. Calcul des paramètres de l'équation de Wilson. Analyse comparative des représentations d'équilibres liquide-vapeur isothermes par les modèles de Wilson et NRTL Computing Parameters in the Wilson Equation. Comparatrice Analysis of Representations of Isothermal Liquid-Vapor Equilibria by Wilson and Nrtl Models

    Directory of Open Access Journals (Sweden)

    Desplanches H.

    2006-11-01

    Full Text Available Un programme de calcul des paramètres de l'équation de Wilson est mis au point. II utilise une méthode itérative de minimisation des écarts sur la pression et la composition de vapeur ou sur chaque grandeur prise séparément. Les méthodes utilisées sont testées sur neuf équilibres liquide-vapeur isothermes de mélanges binaires à déviations positives ou négatives. Les écarts moyens entre les valeurs expérimentales : - de la pression; - de la composition de la vapeur; - de l'enthalpie libre d'excès; et les valeurs calculées à partir des paramètres de Wilson sont comparés à ceux obtenus d'après le modèle NRTL. A program has been developed for computing the parameters in the Wilson equation. It uses an iterative method of minimizing the differences in pressure and steam composition or in each magnitude token separately. The methods used are tried out on nine isothermal liquid-vapor equilibria of binary mixtures with positive or negative deviations. The mean differences between experimental values of the : - pressure; - vapor composition; - excess free enthalpy; and values computed from Wilson parameters are compared with those obtained from an NRTL model.

  15. Chronologic constraints on the tectonic evolution of the Wilson Lake terrane of the Grenville Province, Canada

    DEFF Research Database (Denmark)

    Reno II, Barry Len; Korhonen, F.J.; Stout, J.H.

    the Grenville Orogen in North America. Many of these terranes record evidence of two orogenies: the Labradorian Orogeny at ca. 1710-1600 Ma, and the Grenville Orogeny at ca. 1080-980 Ma. The rocks in the Wilson Lake terrane are interpreted to have been subjected to peak pressures of ~0.95 GPa and...

  16. Creativity and the Curriculum. Inaugural Professorial Lecture

    Science.gov (United States)

    Wyse, Dominic

    2014-01-01

    Creativity is regarded by many as a vital aspect of the human world, and creative endeavours are seen as a central element of society. Hence student creativity is regarded as a desirable outcome of education. This inaugural professorial lecture examines the place of creativity in education and in national curricula. Beginning with examples of…

  17. Lecturers, students and community members sharing the ...

    African Journals Online (AJOL)

    Lecturers, students and community members sharing the responsibility of assessing project-based poster presentations. ... Active participation in the process of learning rather than transmission of information is prominent in modern higher education contexts. In alignment with this trend, traditional modes of assessment, ...

  18. Engineering Lecturers' Views on CLIL and EMI

    Science.gov (United States)

    Aguilar, Marta

    2017-01-01

    The present study aims to shed some light on how engineering lecturers teaching in English at a Spanish university view their work (teaching goals) within the current European internationalisation trend of offering courses and master programmes in English. A questionnaire where content and language integrated learning (CLIL) and English-medium…

  19. Using Smart phone to record lectures

    OpenAIRE

    Busch, John

    2011-01-01

    Mobile phone recording technology is capable of recording video, even mid range mobile phones are capable of high resolution playback. This action research avails a mobile phone to record lectures for later playback for higher education students. Early evaluation alludes to the resource having a positive impact in the cohort learning experience.

  20. Errors in The Feynman Lectures on Physics

    Indian Academy of Sciences (India)

    IAS Admin

    body-centred cubic lattice, face- centred cubic lattice. We discuss some errors in The Feynman Lectures on Physics related to the concept of symmetry. We also suggest a possible correction to Fig.1.4 of Vol. I. The discussion may be useful for students of crystallography, solid state physics and solid state chemistry. 1.

  1. Movement and Character. Lecture, London, 1946

    Science.gov (United States)

    Montesorri, Maria

    2013-01-01

    Dr. Montessori's words from the 1946 London Lectures describe principles of intelligence and character, the work of the hand, and movement with a purpose as being integral to self-construction. The perfection of movement is spiritual, says Dr. Montessori. Repetition of practical life exercises are exercises in movement with the dignity of human…

  2. Mathematics Lecturing in the Digital Age

    Science.gov (United States)

    Trenholm, Sven; Alcock, Lara; Robinson, Carol L.

    2012-01-01

    In this article, we consider the transformation of tertiary mathematics lecture practice. We undertake a focused examination of the related research with two goals in mind. First, we document this research, reviewing the findings of key studies and noting that reflective pieces on individual practice as well as surveys are more prevalent than…

  3. Lecture notes for Advanced Time Series Analysis

    DEFF Research Database (Denmark)

    Madsen, Henrik; Holst, Jan

    1997-01-01

    A first version of this notes was used at the lectures in Grenoble, and they are now extended and improved (together with Jan Holst), and used in Ph.D. courses on Advanced Time Series Analysis at IMM and at the Department of Mathematical Statistics, University of Lund, 1994, 1997, ...

  4. Lecturing style teaching and student performance

    NARCIS (Netherlands)

    van Klaveren, C.

    2011-01-01

    Teachers in the Netherlands tend to spend less time in front of the class, and often adopt a more personal approach. This allows them to better adjust their lecturing style to the needs of the individual student with the aim of increasing student performance. However, a more personal approach is

  5. Towards Individualized Physiology Lecturing in Africa

    African Journals Online (AJOL)

    Dr Olaleye Samuel

    held clickers or smart phones in a flexible and fast way using instant and complex calculations which enable even in depth analysis to tailor the lecture for that specific student group. A continuous feedback data collection and analysis including monitoring of learned issues through different courses enables quality ...

  6. Academic Training: Summer Student Lecture Programme

    CERN Multimedia

    2004-01-01

    Main Auditorium, bldg. 500 DATE TIME LECTURER TITLE Monday 19 July 09:15 - 10:00 A. PICH (IFIC) The Standard Model (1/8) 10:15 - 11:00 O. ULLALAND (CERN) Detectors (2/5) 11:15 - 12:00 O. ULLALAND (CERN) Detectors (3/5) DATE TIME LECTURER TITLE Tuesday 20 July 09:15 - 10:00 A. PICH (IFIC) The Standard Model (2/8) 10:15 - 11:00 O. ULLALAND (CERN) Detectors (4/5) 11:15 - 12:00 O. ULLALAND (CERN) A. PICH (IFIC) Discussion Session DATE TIME LECTURER TITLE Wednesday 21 July 09:15 - 10:00 A. PICH (IFIC) The Standard Model (3/8) 10:15 - 11:00 A. PICH (IFIC) The Standard Model (4/8) 11:15 - 12:00 O. ULLALAND (CERN) Detectors (5/5) 14:00 - 15:00 R. BRUN (CERN) ROOT: Introduction and Demonstration DATE TIME LECTURER TITLE Thursday 22 July 09:15 - 10:00 A. PICH (IFIC) The Standard Model (5/8) 10:15 - 11:00 C. De La Taille (Laboratoire de l'Accélérateur Linéaire) Introduction to Electronics (1/3) 11:15 - 12:00 A. PICH (IFIC) C. De La Taille (Laboratoi...

  7. Academic Training: Summer Student Lecture Programme

    CERN Multimedia

    2004-01-01

    Main Auditorium, bldg. 500 DATE TIME LECTURER TITLE Monday 26 July 09:15 - 10:00 A. Pich (IFIC) The Standard Model (7/8) 10:15 - 11:00 R. Rattazzi (CERN) Beyond the Standard Model (1/3) 11:15 - 12:00 K. Jacobs (Universität Freiburg) Physics in Hadronic Colliders (1/4) DATE TIME LECTURER TITLE Tuesday 27 July 09:15 - 10:00 A. Pich (IFIC) The Standard Model (8/8) 10:15 - 11:00 R. Rattazzi (CERN) Beyond the Standard Model (2/3) 11:15 - 12:00 R. Rattazzi (CERN) A. Pich (IFIC) Discussion Session DATE TIME LECTURER TITLE Wednesday 28 July 09:15 - 10:00 K. Jacobs (Universität Freiburg) Physics in Hadronic Colliders (2/4) 10:15 - 11:00 K. Jacobs (Universität Freiburg) Physics in Hadronic Colliders (3/4) 11:15 - 12:00 R. Rattazzi (CERN) Beyond the Standard Model (3/3) 14:00 - 15:00 R. Assmann (CERN) The CLIC project DATE TIME LECTURER TITLE Thursday 29 July 09:15 - 10:00 K. Jacobs (Universität Freiburg) Physics in Hadronic ...

  8. Lecturing style teaching and student performance

    NARCIS (Netherlands)

    Van Klaveren, Chris

    Teachers in the Netherlands tend to spend less time in front of the class, and often adopt a more personal approach. This allows them to better adjust their lecturing style to the needs of the individual student with the aim of increasing student performance. However, a more personal approach is

  9. Five Lectures on Radial Basis Functions

    DEFF Research Database (Denmark)

    Powell, Mike J.D.

    2005-01-01

    Professor Mike J. D. Powell spent three weeks at IMM in November - December 2004. During the visit he gave five lectures on radial basis functions. These notes are a TeXified version of his hand-outs, made by Hans Bruun Nielsen, IMM....

  10. Towards Individualized Physiology Lecturing in Africa | Ripatti ...

    African Journals Online (AJOL)

    A continuous feedback data collection and analysis including monitoring of learned issues through different courses enables quality assessment of teaching and ... Several experiments on new ways to have lecture sessions confirm the positive impact on learning and enhanced participation of the students in the university ...

  11. Music during Lectures: Will Students Learn Better?

    Science.gov (United States)

    Dosseville, Fabrice; Laborde, Sylvain; Scelles, Nicolas

    2012-01-01

    We investigated the influence of music during learning on the academic performance of undergraduate students, and more particularly the influence of affects induced by music. Altogether 249 students were involved in the study, divided into a control group and an experimental group. Both groups attended the same videotaped lecture, with the…

  12. PEER INTERACTIONS AND POSITIVE STUDENT-LECTURER ...

    African Journals Online (AJOL)

    This paper sets out to interrogate the role played by peer interactions in the teaching and learning of College Algebra in a classroom setting. It also explores the impact of positive student-lecturer relationship on teaching and learning of College Algebra at the university level and the general improvement of student ...

  13. Facilitating lecturer development and student learning through ...

    African Journals Online (AJOL)

    The aim of the action research project is to improve my own practice as research methodology lecturer to facilitate effective student learning to enable students to become reflective practitioners with responsibility for their own professional development through action research in their own classrooms, and to motivate the ...

  14. KAWA lecture notes on complex hyperbolic geometry

    OpenAIRE

    Rousseau, Erwan

    2016-01-01

    These lecture notes are based on a mini-course given at the fifth KAWA Winter School on March 24-29, 2014 at CIRM, Marseille. They provide an introduction to hyperbolicity of complex algebraic varieties namely the geometry of entire curves, and a description of some recent developments.

  15. Software approach to minimizing problems of student-lecturer ...

    African Journals Online (AJOL)

    Lecturer Interaction in Higher institutions of learning. The Software was developed using PHP and hosted in the University web server, and the interaction between students and their lecturers was compared using both the traditional approaches ...

  16. Inaugural Lecture in the John Adams Memorial Lecture Series John Adams and his times

    CERN Document Server

    Amaldi, Edoardo; CERN. Geneva

    1985-01-01

    The John Adams' Memorial Lecture will be an annual event which in futur years will provide young and promising accelerator engineers and physicists with an opportunity to expose their work in the accelerator field. The inaugural lecture will put the many very important contribution of John Adams into perspective, not only with respect to CERN, but also with respect to the development of high energy physics in the world.

  17. Lectures on Logic and Computation

    DEFF Research Database (Denmark)

    The European Summer School in Logic, Language and Information (ESSLLI) is organized every year by the Association for Logic, Language and Information (FoLLI) in different sites around Europe. The main focus of ESSLLI is on the interface between linguistics, logic and computation. ESSLLI offers...... foundational, introductory and advanced courses, as well as workshops, covering a wide variety of topics within the three areas of interest: Language and Computation, Language and Logic, and Logic and Computation. During two weeks, around 50 courses and 10 workshops are offered to the attendants, each of 1...... and selected. The papers are organized in topical sections on computational complexity, multi-agant systems, natural language processing, strategies in games and formal semantics....

  18. DYSTONIA IN CHILDREN (A LECTURE

    Directory of Open Access Journals (Sweden)

    M. Yu. Bobylova

    2014-01-01

    Full Text Available Distonia is a movement disorder associated with imbalance of excitatory neurotransmitters, and it is characterized by continuous or episodic muscle contraction that forms repetitive stereotyped movements and/or postures. Dystonic hyperkinesia of younger children can be included into the structure of many syndromes that have different etiological factors, prognosis, and treatment. Different clinical variant of dystonia are represented: idiopathic benign dystonia with the onset in the first year of life; dystonia against the background of residual damage to the nervous system; hereditary idiopathic and symptomatic dystonia with various syndromes and metabolic diseases; similar conditions. Diagnostics of dystonia of children requires application of a wide range of examinations, including neuroimaging, continuous video electroencephalographic monitoring, genetic research. Differential diagnosis of dystonia of children is performed regarding various paroxysmal states of childhood of the epileptic and non-epileptic nature.

  19. 3. Aachen users' forum on bioenergy use in cities and rural environment. Lectures; 3. Aachener Anwenderforum: Bioenergie-Nutzung in Stadt und Region. Vortraege

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2007-10-08

    Main topics of the meetings' lectures were: biomass cultivation, agriculture and forestry, fermentation, biogas plants, financing, operation, licensing, cleanup of biogas, biogas cogeneration plants, district heating, feed-in of biogas into the natural gas distribution system. (uke)

  20. Taxonomy of Lecture Note-Taking Skills and Subskills

    Science.gov (United States)

    Al-Musalli, Alaa M.

    2015-01-01

    Note taking (NT) in lectures is as active a skill as listening, which stimulates it, and as challenging as writing, which is the end product. Literature on lecture NT misses an integration of the processes involved in listening with those in NT. In this article, a taxonomy is proposed of lecture NT skills and subskills based on a similar list…

  1. Lecturers' Experience of Using Social Media in Higher Education Courses

    Science.gov (United States)

    Seechaliao, Thapanee

    2015-01-01

    This research paper presents lecturers' experience of using social media in higher education courses. The research methodology used a survey approach. The research instrument was a questionnaire about lecturers' experience of using social media in higher education courses. Thirty-one lecturers completed the questionnaire. The data were scored by…

  2. 45 CFR 73.735-706 - Teaching, lecturing, and speechmaking.

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 1 2010-10-01 2010-10-01 false Teaching, lecturing, and speechmaking. 73.735-706... OF CONDUCT Outside Activities § 73.735-706 Teaching, lecturing, and speechmaking. (a) Employees are encouraged to engage in teaching and lecturing activities which are not part of their official duties when...

  3. Lecturers' discourses about the interplay between language and ...

    African Journals Online (AJOL)

    A discourse-analysis of what lecturers say about student learning is used to discuss some of their dominant understandings of this process. In this article, the two discourses that are discussed reflect lecturers' beliefs about the interplay between language and learning. Lecturers' discourses do not only reflect their classroom ...

  4. Lecture on Female Masturbation Harassed Him, Male Student Says.

    Science.gov (United States)

    Wilson, Robin

    1995-01-01

    A male student in a California State University-Sacramento psychology lecture on female masturbation has filed a sexual harassment complaint, claiming the lecture violated institutional policy by creating an intimidating, hostile, and offensive learning environment. He felt the lecture was inappropriately graphic and political in intent. (MSE)

  5. Engagement of Students with Lectures in Biochemistry and Pharmacology

    Science.gov (United States)

    Davis, Elizabeth Ann; Hodgson, Yvonne; Macaulay, Janet Olwyn

    2012-01-01

    Academic staff at universities have become concerned about the decrease in student attendance at lectures and the implication of this on student achievement and learning. Few studies have measured actual lecture attendance in a coherent or comprehensive way. The aim of this study was to measure actual lecture attendance of students over two year…

  6. Excerpts from the Nobel Lecture of J. Heyrovský

    Indian Academy of Sciences (India)

    Annual Meetings · Mid Year Meetings · Discussion Meetings · Public Lectures · Lecture Workshops · Refresher Courses · Symposia · Live Streaming. Home; Journals; Resonance – Journal of Science Education; Volume 9; Issue 9. Excerpts from the Nobel Lecture of J. Heyrovský. Classics Volume 9 Issue 9 September 2004 ...

  7. Does Instructor's Image Size in Video Lectures Affect Learning Outcomes?

    Science.gov (United States)

    Pi, Z.; Hong, J.; Yang, J.

    2017-01-01

    One of the most commonly used forms of video lectures is a combination of an instructor's image and accompanying lecture slides as a picture-in-picture. As the image size of the instructor varies significantly across video lectures, and so do the learning outcomes associated with this technology, the influence of the instructor's image size should…

  8. Advice for New and Student Lecturers on Probability and Statistics

    Science.gov (United States)

    Larsen, Michael D.

    2006-01-01

    Lecture is a common presentation style that gives instructors a lot of control over topics and time allocation, but can limit active student participation and learning. This article presents some ideas to increase the level of student involvement in lecture. The examples and suggestions are based on the author's experience as a senior lecturer for…

  9. Do-It-Yourself Whiteboard-Style Physics Video Lectures

    Science.gov (United States)

    Douglas, Scott Samuel; Aiken, John Mark; Greco, Edwin; Schatz, Michael; Lin, Shih-Yin

    2017-01-01

    Video lectures are increasingly being used in physics instruction. For example, video lectures can be used to "flip" the classroom, i.e., to deliver, via the Internet, content that is traditionally transmitted by in-class lectures (e.g., presenting concepts, working examples, etc.), thereby freeing up classroom time for more interactive…

  10. Globe Event | Lecture by Cédric Villani | 21 May

    CERN Multimedia

    Globe Info

    2013-01-01

    La naissance des idées - réflexions sur la nature et l’histoire de la mathématique et de la physique, by Cédric Villani.   Globe de la science et de l'innovation Route de Meyrin, 1211 Genève Tuesday 21 May 2013 at 6:00 p.m. The lecture will be in French - Interpreting available in English   Cédric Villani. In this lecture, Cédric Villani will explain what he considers to be the necessary “ingredients” for the birth of new ideas. Clearly a good brain is an essential factor, but that alone is not enough. The researcher must also have access to a wealth of literature, which is now greatly facilitated by the Internet. Motivation is another key component, although we do not really understand what incites it. Intellectual environment and constraints also drive creativity, as do perseverance and chance. An interesting idea has little chance of making a breakthrough w...

  11. Lectures on functional analysis and the Lebesgue integral

    CERN Document Server

    Komornik, Vilmos

    2016-01-01

    This textbook, based on three series of lectures held by the author at the University of Strasbourg, presents functional analysis in a non-traditional way by generalizing elementary theorems of plane geometry to spaces of arbitrary dimension. This approach leads naturally to the basic notions and theorems. Most results are illustrated by the small ℓp spaces. The Lebesgue integral, meanwhile, is treated via the direct approach of Frigyes Riesz, whose constructive definition of measurable functions leads to optimal, clear-cut versions of the classical theorems of Fubini-Tonelli and Radon-Nikodým. Lectures on Functional Analysis and the Lebesgue Integral presents the most important topics for students, with short, elegant proofs. The exposition style follows the Hungarian mathematical tradition of Paul Erdős and others. The order of the first two parts, functional analysis and the Lebesgue integral, may be reversed. In the third and final part they are combined to study various spaces of continuous and integ...

  12. Wilson loops on three-manifolds and their M2-brane duals

    Energy Technology Data Exchange (ETDEWEB)

    Farquet, Daniel; Sparks, James [Mathematical Institute, University of Oxford,Radcliffe Observatory Quarter, Woodstock Road, Oxford OX2 6GG (United Kingdom)

    2014-12-30

    We compute the large N limit of Wilson loop expectation values for a broad class of N=2 supersymmetric gauge theories defined on a general class of background three-manifolds M{sub 3}, diffeomorphic to S{sup 3}. We find a simple closed formula which depends on the background geometry only through a certain supersymmetric Killing vector field. The supergravity dual of such a Wilson loop is an M2-brane wrapping the M-theory circle, together with a complex curve Σ{sub 2} in a self-dual Einstein manifold M{sub 4}, whose conformal boundary is M{sub 3}. We show that the regularized action of this M2-brane also depends only on the supersymmetric Killing vector, precisely reproducing the large N field theory computation.

  13. Eugene Onegin the Cold War Monument: How Edmund Wilson Quarreled with Vladimir Nabokov

    Directory of Open Access Journals (Sweden)

    Tim Conley

    2014-01-01

    Full Text Available The tale of how Edmund Wilson quarreled with Vladimir Nabokov over the latter’s 1964 translation of Eugene Onegin can be instructively read as a politically charged event, specifically a “high culture” allegory of the Cold War. Dissemination of anti-Communist ideals (often in liberal and literary guises was the mandate of the Congress for Cultural Freedom, whose funding and editorial initiatives included the publication of both pre-Revolution Russian literature and, more notoriously, the journal Encounter (1953-1990, where Nabokov’s fiery “Reply” to Wilson appeared. This essay outlines the propaganda value of the Onegin debate within and to Cold War mythology.

  14. New results on the 3-loop heavy flavor Wilson coefficients in deep-inelastic scattering

    Energy Technology Data Exchange (ETDEWEB)

    Ablinger, Jakob; Schneider, Carsten [Johannes Kepler Univ., Linz (Austria). Research Inst. for Symbolic Computation; Bluemlein, Johannes; Freitas, Abilio de; Wissbrock, Fabian [Deutsches Elektronen-Synchrotron (DESY), Zeuthen (Germany); Hasselhuhn, Alexander [Johannes Kepler Univ., Linz (Austria). Research Inst. for Symbolic Computation; Deutsches Elektronen-Synchrotron (DESY), Zeuthen (Germany); Klein, Sebastian [RWTH Aachen Univ. (Germany). Inst. fuer Theoretische Physik E

    2013-01-02

    We report on recent results obtained for the 3-loop heavy flavor Wilson coefficients in deepinelastic scattering (DIS) at general values of the Mellin variable N at larger scales of Q{sup 2}. These concern contributions to the gluonic ladder-topologies, the transition matrix elements in the variable flavor scheme of O(n{sub f}T{sup 2}{sub F}) and O(T{sup 2}{sub F}), and first results on higher 3-loop topologies. The knowledge of the heavy flavor Wilson coefficients at 3-loop order is of importance to extract the parton distribution functions and {alpha}{sub s}(M{sup 2}{sub Z}) in complete NNLO QCD analyses of the world precision data on the structure function F{sub 2}(x,Q{sup 2}).

  15. Ludwik Antoni Birkenmajer and Curtis Wilson on the Origin of Nicholas Copernicus's Heliocentrism.

    Science.gov (United States)

    Goddu, André

    2016-06-01

    What moved Copernicus to switch from the time-honored geocentric to a heliocentric setup for the planetary system? He himself did not explain this momentous move in any detail--his only comments about it suggest that Ptolemy's complete solution to the problem of nonuniform motion, the equant model, led him to propose. Earth's annual motion around the Sun. The most widely accepted accounts of the origin of Copernicus's theory dismiss or dispute any direct relation between the principle of uniform motion and the heliocentric theory. Two scholars, the Polish expert on Copernicus Ludwik Antoni Birkenmajer (1855-1929) and the American historian of astronomy Curtis Wilson (1921-2012), constructed detailed arguments about how Copernicus's rejection of Ptolemy's solution led him to his theory. The principal aim of this essay is to reintroduce Birkenmajer's and Wilson's voices to the discussion of the origin of Copernicus's heliocentrism.

  16. BPS Wilson loops and Bremsstrahlung function in ABJ(M): a two loop analysis

    Energy Technology Data Exchange (ETDEWEB)

    Bianchi, Marco S. [Institut für Physik, Humboldt-Universität zu Berlin,Newtonstraße 15, 12489 Berlin (Germany); Griguolo, Luca [Dipartimento di Fisica e Scienze della Terra, Università di Parmaand INFN Gruppo Collegato di Parma,Viale G.P. Usberti 7/A, 43100 Parma (Italy); Leoni, Matias [Physics Department, FCEyN-UBA & IFIBA-CONICETCiudad Universitaria, Pabellón I, 1428, Buenos Aires (Argentina); Penati, Silvia [Dipartimento di Fisica, Università di Milano-Bicoccaand INFN, Sezione di Milano-Bicocca,Piazza della Scienza 3, I-20126 Milano (Italy); Seminara, Domenico [Dipartimento di Fisica, Università di Firenzeand INFN Sezione di Firenze,via G. Sansone 1, 50019 Sesto Fiorentino (Italy)

    2014-06-19

    We study a family of circular BPS Wilson loops in N=6 super Chern-Simons-matter theories, generalizing the usual 1/2-BPS circle. The scalar and fermionic couplings depend on two deformation parameters and these operators can be considered as the ABJ(M) counterpart of the DGRT latitudes defined in N=4 SYM. We perform a complete two-loop analysis of their vacuum expectation value, discuss the appearance of framing-like phases and propose a general relation with cohomologically equivalent bosonic operators. We make an all-loop proposal for computing the Bremsstrahlung function associated to the 1/2-BPS cusp in terms of these generalized Wilson loops. When applied to our two-loop result it reproduces the known expression. Finally, we comment on the generalization of this proposal to the bosonic 1/6-BPS case.

  17. La “novela canalera” en Carlos Guillermo “Cubena” Wilson

    OpenAIRE

    Pulido Ritter, Luis

    2013-01-01

    En este ensayo, queremos plantear la pregunta sobre si se puede incluir la obra de Carlos Guillermo “Cubena” Wilson en la “novela canalera”, comprendida como subgénero literario cuya temática gira en torno a la construcción del Canal de Panamá. No se trata tampoco de reducir esa obra a este género, porque va más allá de la re-creación de una nación, y de la experiencia de la construcción del Canal. La obra de Wilson es inseparable de una cierta historia concreta marcada por la existencia de P...

  18. Revisiting the dilatation operator of the Wilson-Fisher fixed point

    Energy Technology Data Exchange (ETDEWEB)

    Liendo, Pedro [Deutsches Elektronen-Synchrotron (DESY), Hamburg (Germany). Theory Group

    2017-01-15

    We revisit the order ε dilatation operator of the Wilson-Fisher fixed point obtained by Kehrein, Pismak, and Wegner in light of recent results in conformal field theory. Our approach is algebraic and based only on symmetry principles. The starting point of our analysis is that the first correction to the dilatation operator is a conformal invariant, which implies that its form is fixed up to an infinite set of coefficients associated with the scaling dimensions of higher-spin currents. These coefficients can be fixed using well-known perturbative results, however, they were recently re-obtained using CFT arguments without relying on perturbation theory. Our analysis then implies that all order-ε scaling dimensions of the Wilson-Fisher fixed point can be fixed by symmetry.

  19. Hereditary Multiple Cerebral Cavernous Malformations Associated with Wilson Disease and Multiple Lipomatosis.

    Science.gov (United States)

    Belousova, Olga B; Okishev, Dmitry N; Ignatova, Tatyana M; Balashova, Maria S; Boulygina, Eugenia S

    2017-09-01

    We report on a patient with 2 Mendelian diseases-symptomatic multiple familial cerebral cavernous malformations (FCCMs) and Wilson disease. Genetic analysis revealed single nucleotide polymorphisms in genes CCM2 and CCM3, associated with cavernous malformations, and homozygote mutation in the ATP7B gene, responsible for Wilson disease. FCCMs were symptomatic in 3 generations. The patient also had multiple lipomatosis, which is suggested to be a familial syndrome. In recent years there has been an increasing amount of publications linking FCCMs with other pathology, predominantly with extracranial and intracranial mesenchymal anomalies. The present study is the description of an unusual association between 2 independent hereditary diseases of confirmed genetic origin-a combination that has not been described previously. Copyright © 2017 Elsevier Inc. All rights reserved.

  20. Entanglement entropy of the large $N$ Wilson-Fisher conformal field theory

    CERN Document Server

    Whitsitt, Seth; Sachdev, Subir

    2016-01-01

    We compute the entanglement entropy of the Wilson-Fisher conformal field theory (CFT) in 2+1 dimensions with O($N$) symmetry in the limit of large $N$ for general entanglement geometries. We show that the leading large $N$ result can be obtained from the entanglement entropy of $N$ Gaussian scalar fields with their mass determined by the geometry. For a few geometries, the universal part of the entanglement entropy of the Wilson-Fisher CFT equals that of a CFT of $N$ massless scalar fields. However, in most cases, these CFTs have a distinct universal entanglement entropy even at $N=\\infty$. Notably, for a semi-infinite cylindrical region it scales as $N^0$, in stark contrast to the $N$-linear result of the Gaussian fixed point.

  1. Edward O.Wilson, L’Avenir de la vie, Seuil, Paris, 2003.

    Directory of Open Access Journals (Sweden)

    Stéphane Callens

    2003-05-01

    Full Text Available La notion de biodiversité a été introduite par un biologiste d’Oxford, Norman Myers. Edward O.Wilson avait écrit en 1992 l’ouvrage devenu un classique de la question, The Diversity of Life (ouvrage publié en traduction française : Edward O. Wilson, La diversité de la vie, Paris : Odile Jacob, 1993. Ce nouvel ouvrage, The Future of Life en v.o., ou L’Avenir de la vie en édition française, fait donc le point dix ans après le sommet de Rio qui a introduit la notion de biodiversité à l’échelle p...

  2. [Assessment of vocal intensity in lecturers depending on acoustic properties of lecture rooms].

    Science.gov (United States)

    Mikulski, Witold

    2015-01-01

    Lombard's effect increases the level of vocal intensity in the environment, in which noise occurs. This article presents the results of the author's own study of vocal intensity level and A-weighted sound pressure level of background noise during normal lectures. The aim of the study was to define whether above-mentioned parameters depend on acoustic properties of rooms (classrooms or lecture rooms) and to define how many lectors speak with raised voice. The study was performed in a group of 50 teachers and lecturers in 10 classrooms with cubature of 160-430 m3 and reverberation time of 0.37-1.3 s (group A consisted of 3 rooms which fulfilled, group B consisted of 3 rooms which almost fulfilled and group C consisted of 4 rooms which did not fulfill criteria based on reverberation time (maximum permissible value is 0.6-0.8 s according to PN-B-02151-4:2015). Criteria of raising voice were based on vocal intensity level (maximum value: 65 dB according to EN ISO 9921:2003). The values of above-mentioned parameters were determined from modes of A--weighted sound pressure level distributions during lectures. Great differentiation of vocal intensity level between lectors was found. In classrooms of group A lectors were not using raised voice, in group B--21%, and in group C--60% of lectors were using raised voice. It was observed that acoustic properties of classrooms (defined by reverberation time) exert their effect on lecturer's vocal intensity level (i.e., raising voice), which may contribute to the increased risk of vocal tract illnesses. The occurrence of Lombard's effect in groups of teachers and lecturers, conducting lectures in rooms, was evidenced. This work is available in Open Access model and licensed under a CC BY-NC 3.0 PL license.

  3. Academic Training Lecture Regular Programme: Cloud Computing

    CERN Multimedia

    2012-01-01

    Cloud Computing (1/2), by Belmiro Rodrigues Moreira (LIP Laboratorio de Instrumentacao e Fisica Experimental de Part).   Wednesday, May 30, 2012 from 11:00 to 12:00 (Europe/Zurich) at CERN ( 500-1-001 - Main Auditorium ) Cloud computing, the recent years buzzword for distributed computing, continues to attract and keep the interest of both the computing and business world. These lectures aim at explaining "What is Cloud Computing?" identifying and analyzing it's characteristics, models, and applications. The lectures will explore different "Cloud definitions" given by different authors and use them to introduce the particular concepts. The main cloud models (SaaS, PaaS, IaaS), cloud types (public, private, hybrid), cloud standards and security concerns will be presented. The borders between Cloud Computing and Grid Computing, Server Virtualization, Utility Computing will be discussed and analyzed.

  4. Academic Training: Academic Training Lectures-Questionnaire

    CERN Multimedia

    2004-01-01

    ACADEMIC TRAINING Françoise Benz tel. 73127 academic.training@cern.ch SUGGEST AND WIN! Its time to plan the 2004-2005 lecture series. From today until March 19 you have the chance to give your contribution to planning for next year's Academic Training Lecture Series. At the web site: http://cern.ch/Academic.Training/questionnaire you will find questionnaires proposing topics in high energy physics, applied physics and science and society. Answering the questionnaire will help ensure that the selected topics are as close as possible to your interests. In particular requests and comments from students will be much appreciated. To encourage your contribution, the AT Committee will reward one lucky winner with a small prize, a 50 CHF coupon for a book purchase at the CERN bookshop.

  5. Relativistic heavy-ion physics: three lectures

    CERN Document Server

    McLerran, L

    2007-01-01

    These lectures provide an introduction to the physics issues which are being studied in the collisions of ultrarelativistic heavy ions. The lectures are focused on the production of new states of matter. The quark-gluon plasma is thermal matter which once existed in the Big Bang. The colour glass condensate is a universal form of high energy density gluonic matter which is part of a hadron wavefunction and which controls the high-energy limit of strong interactions. The glasma is matter produced in the collisons of high-energy hadrons which evolves into a quarkgluon plasma. The glasma has interesting topological properties and may be responsible for the early thermalization seen at RHIC. I introduce the student to these topics, discuss results from experiments, and comment upon future opportunities.

  6. Lectures on Flavor Physics and CP Violation

    CERN Document Server

    Grinstein, Benjamín

    2016-12-20

    These lectures on flavor physics are an introduction to the subject. First lec- ture: We discuss the meaning of flavor and the importance of flavor physics in restricting extensions of the Standard Model (SM) of Electroweak interactions. We explain the origin of the KM matrix and how its elements are determined. We discuss FCNC and the GIM mechanism, followed by how a principle of Minimal Flavor Violation leads to SM extensions that are safe as far as FCNC are concerned even if the new physics comes in at low, TeVish scales. This is illustrated by the example of B radiative decays ( b → sγ ). Second lecture: We then turn our attention to CP-violation. We start by presenting neutral meson mixing. Then we consider various CP-asymmetries, culminating in the theoretically clean interference between mixing and decay into CP eigenstates.

  7. Lecture Notes on Topics in Accelerator Physics

    Energy Technology Data Exchange (ETDEWEB)

    Chao, Alex W.

    2002-11-15

    These are lecture notes that cover a selection of topics, some of them under current research, in accelerator physics. I try to derive the results from first principles, although the students are assumed to have an introductory knowledge of the basics. The topics covered are: (1) Panofsky-Wenzel and Planar Wake Theorems; (2) Echo Effect; (3) Crystalline Beam; (4) Fast Ion Instability; (5) Lawson-Woodward Theorem and Laser Acceleration in Free Space; (6) Spin Dynamics and Siberian Snakes; (7) Symplectic Approximation of Maps; (8) Truncated Power Series Algebra; and (9) Lie Algebra Technique for nonlinear Dynamics. The purpose of these lectures is not to elaborate, but to prepare the students so that they can do their own research. Each topic can be read independently of the others.

  8. Biopolymer strategy for the treatment of Wilson´s disease

    Czech Academy of Sciences Publication Activity Database

    Vetrík, Miroslav; Mattová, J.; Macková, Hana; Kučka, Jan; Poučková, P.; Kukačková, Olivia; Brus, Jiří; Eigner-Henke, S.; Sedláček, Ondřej; Šefc, L.; Štěpánek, Petr; Hrubý, Martin

    2018-01-01

    Roč. 273, 10 March (2018), s. 131-138 ISSN 0168-3659 R&D Projects: GA ČR(CZ) GA16-02870S; GA MZd(CZ) NV15-25781A; GA MŠk(CZ) LM2015064; GA MŠk(CZ) LO1507 Institutional support: RVO:61389013 Keywords : Wilson's disease * copper chelators * biopolymers Subject RIV: CD - Macromolecular Chemistry OBOR OECD: Polymer science Impact factor: 7.786, year: 2016

  9. Detailed Project Report and Environmental Assessment, Wilson Branch, Chesterfield County, South Carolina. Revision.

    Science.gov (United States)

    1982-08-27

    Biologist Under the supervision of: Roger L. Banks, Field Supervisor June, 1982 O ,9 6 - - ." . - :-. FISH AND WILDLIFE COORDINATION ACT REPORT WILSON...concur in the findings and recommendations included in the report. Sil y, /.- J6mes A. Timmerman, Jr. */ Executive Director ,,iJr/sa c: Mr. Roger ...scripta River Cooter rpm concinna concinna Li zards Green Anole Anolis carolinensis carolinensis Northerr Fence Lizard 7--To-orus undulatu Six-lined

  10. Imaging findings of liver involvement of Wilson's disease

    Energy Technology Data Exchange (ETDEWEB)

    Akhan, Okan [Hacettepe University, Faculty of Medicine, Department of Radiology, Sihhiye/Ankara (Turkey); Akpinar, Erhan [Hacettepe University, Faculty of Medicine, Department of Radiology, Sihhiye/Ankara (Turkey)], E-mail: erhan.akpinar@gmail.com; Karcaaltincaba, Musturay; Haliloglu, Mithat; Akata, Deniz; Karaosmanoglu, Ali Devrim; Ozmen, Mustafa [Hacettepe University, Faculty of Medicine, Department of Radiology, Sihhiye/Ankara (Turkey)

    2009-01-15

    Purpose: The major purpose of this paper is to outline and correlate US, CT and MR imaging findings of liver in patients with Wilson's disease. Materials and methods: Twenty-eight patients (10 male, 18 female, median age 16) with Wilson's disease were examined with US, CT and MRI. Liver echogenicity, echo pattern, contour irregularity, periportal thickness, perihepatic fat layer thickness, the presence of focal parenchymal lesion, and other associated findings were recorded by US in every patient. CT and MRI were done in 20 and 12 patients, respectively. Results: Contour irregularity was observed in 24 patients and heterogeneous parenchymal echo pattern was seen in 26 patients with US. The presence of increased perihepatic fat layer was observed in eight patients. Severe parenchymal atrophy was seen in all lobes of the liver including caudate in contrast to post-viral chronic liver disease. Nineteen patients had periportal thickening. US showed multiple hyper and/or hypoechoic nodules smaller than 1 cm in 13 patients. MRI demonstrated small nodular hypointense areas on T2-weighted images in five patients. In only one patient these nodules showed contrast enhancement in CT and MR and pathologically proved to be dysplastic nodule. Conclusion: Wilson's disease involving the liver has several unique radiological findings in comparison to other types of cirrhosis. These specific features include multiple nodular lesions in the liver, presence of perihepatic fat layer and normal caudate lobe which is contrary to other types cirrhosis. Liver injury in the Wilson's disease can be defined by imaging modalities, especially by US which we think is the most precise imaging modality to detect early parenchymal changes in the progress of the disease.

  11. Renormalisation of quark bilinears with Nf=2 Wilson fermions and tree-level improved gauge action

    CERN Document Server

    Dimopoulos, P.; Herdoiza, G.; Vladikas, A.; Lubicz, V.; Simula, S.; Papinutto, M.

    2007-01-01

    We present results for the renormalisation constants of bilinear quark operators, using the Nf=2 twisted mass Wilson action at maximal twist (which guarantees automatic O(a) improvement) and the tree-level Symanzik improved gauge action. The scale-independent renormalisation constants are computed with a new method, which makes use of both standard twisted mass and Osterwalder-Seiler fermions. Moreover, the results from an RI-MOM calculation are presented for both scale independent and scale dependent renormalisation constants.

  12. Metal element excretion in 24-h urine in patients with Wilson disease under treatment of D-penicillamine.

    Science.gov (United States)

    Huang, Lisu; Yu, Xiaodan; Zhang, Jun; Liu, Xiaoqing; Zhang, Yongjun; Jiao, Xianting; Yu, Xiaogang

    2012-05-01

    Wilson disease is an inherited autosomal recessive disorder causing copper accumulation and consequent toxicity. D-Penicillamine, a potent metal chelator, is an important therapy for Wilson disease. To investigate the changes of metal elements under the treatment of D-penicillamine, we determined the levels of Cu, Zn, Mg, Ca, Fe, Se, Mn, Pb, Hg, Cd, As, Tl, and Al by ICP-MS in 24-h urine of 115 Wilson disease patients who had received treatment with D: -penicillamine for 1 month to 22 years at maintenance doses, as well as 115 age-matched, healthy controls. The levels of Cu, Mg, Ca, Zn, Hg, Pb, Tl, Cd, and Mn in the 24-h urine of the cases were significantly higher than those of the controls (P elements may be altered in patients with Wilson disease under the treatment of D-penicillamine.

  13. [Academy Lectures, 2013.09.11] 

    OpenAIRE

    Neidich, Warren

    2013-01-01

    The idea of artistic research is a hot topic today, especially in our moment of the information economy and intellectual speculation. The problem is that the word research is bound to specific scientific and reductionist connotations that are connected to its specific methodologies which are at odds with the way art is made. In the lecture entitled “Trans-thinking: Artistic Research in the 21st Century” Neidich will use five examples of his own performative art production created in the four ...

  14. Interactive lectures: Clickers or personal devices?

    OpenAIRE

    Morrell, Lesley J.; Joyce, Domino A

    2015-01-01

    Audience response systems (‘clickers’) are frequently used to promote participation in large lecture classes, and evidence suggests that they convey a number of benefits to students, including improved academic performance and student satisfaction. The limitations of these systems (such as limited access and cost) can be overcome using students’ personal electronic devices, such as mobile phones, tablets and laptops together with text message, web- or app-based polling systems. Using question...

  15. The McAndrews Leadership Lecture: Origins

    OpenAIRE

    Hamm, Anthony W.; Burkhart, Lori A.

    2015-01-01

    Objective This article describes the origins and rationale for the McAndrews Leadership Lecture and explains why the American Chiropractic Association honors George and Jerome McAndrews. Discussion George and Jerome McAndrews? backgrounds demonstrate their leadership contributions to the chiropractic profession. Jerome McAndrews, a chiropractor, held substantial leadership roles in the chiropractic profession. George McAndrews, a lawyer, administered a permanent injunction forbidding the Amer...

  16. Wilson disease protein ATP7B utilizes lysosomal exocytosis to maintain copper homeostasis.

    Science.gov (United States)

    Polishchuk, Elena V; Concilli, Mafalda; Iacobacci, Simona; Chesi, Giancarlo; Pastore, Nunzia; Piccolo, Pasquale; Paladino, Simona; Baldantoni, Daniela; van IJzendoorn, Sven C D; Chan, Jefferson; Chang, Christopher J; Amoresano, Angela; Pane, Francesca; Pucci, Piero; Tarallo, Antonietta; Parenti, Giancarlo; Brunetti-Pierri, Nicola; Settembre, Carmine; Ballabio, Andrea; Polishchuk, Roman S

    2014-06-23

    Copper is an essential yet toxic metal and its overload causes Wilson disease, a disorder due to mutations in copper transporter ATP7B. To remove excess copper into the bile, ATP7B traffics toward canalicular area of hepatocytes. However, the trafficking mechanisms of ATP7B remain elusive. Here, we show that, in response to elevated copper, ATP7B moves from the Golgi to lysosomes and imports metal into their lumen. ATP7B enables lysosomes to undergo exocytosis through the interaction with p62 subunit of dynactin that allows lysosome translocation toward the canalicular pole of hepatocytes. Activation of lysosomal exocytosis stimulates copper clearance from the hepatocytes and rescues the most frequent Wilson-disease-causing ATP7B mutant to the appropriate functional site. Our findings indicate that lysosomes serve as an important intermediate in ATP7B trafficking, whereas lysosomal exocytosis operates as an integral process in copper excretion and hence can be targeted for therapeutic approaches to combat Wilson disease. Copyright © 2014 The Authors. Published by Elsevier Inc. All rights reserved.

  17. Holographic mutual information and distinguishability of Wilson loop and defect operators

    Energy Technology Data Exchange (ETDEWEB)

    Hartnoll, Sean A.; Mahajan, Raghu [Department of Physics, Stanford University, Stanford, CA 94305-4060 (United States)

    2015-02-16

    The mutual information of disconnected regions in large N gauge theories with holographic gravity duals can undergo phase transitions. These occur when connected and disconnected bulk Ryu-Takayanagi surfaces exchange dominance. That is, the bulk ‘soap bubble’ snaps as the boundary regions are drawn apart. We give a gauge-theoretic characterization of this transition: States with and without a certain defect operator insertion — the defect separates the entangled spatial regions — are shown to be perfectly distinguishable if and only if the Ryu-Takayanagi surface is connected. Meanwhile, states with and without a certain Wilson loop insertion — the Wilson loop nontrivially threads the spatial regions — are perfectly distinguishable if and only if the Ryu-Takayanagi surface is disconnected. The quantum relative entropy of two perfectly distinguishable states is infinite. The results are obtained by relating the soap bubble transition to Hawking-Page (deconfinement) transitions in the Rényi entropies, where defect operators and Wilson loops are known to act as order parameters.

  18. Lecture programme The reality of science today

    CERN Multimedia

    2008-01-01

    John Ellis (CERN): Gauguin’s questions in the context of particle physics.John Ellis (CERN) will speak about: Gauguin’s questions in the context of particle physics In a famous painting, Paul Gauguin asked the universal and eternal questions: Where do we come from? What are we? Where are we going? In this lecture, John Ellis will comment on the prospects of particle physics in an attempt to provide elements of answers to these questions. This is the second in the series of lectures organised by the History and Philosophy of Sciences Unit of Geneva University, in collaboration with ASPERA, the European network for astroparticle physics research, which began with a contribution from Dominique Pestre (EHESS and Centre Koyré, Paris). What are the new challenges and realities facing research? What is its place in today’s society? In this series of lectures covering a range of topics, researchers and members of the general public are invited to think about the state of sc...

  19. Recently Published Lectures and Tutorials for ATLAS

    CERN Multimedia

    Herr, J.

    2006-01-01

    As reported in the September 2004 ATLAS eNews, the Web Lecture Archive Project, WLAP, a collaboration between the University of Michigan and CERN, has developed a synchronized system for recording and publishing educational multimedia presentations, using the Web as medium. This year, the University of Michigan team has been asked to record and publish all ATLAS Plenary sessions, as well as a large number of Physics and Computing tutorials. A significant amount of this material has already been published and can be accessed via the links below. The WLAP model is spreading. This summer, the CERN's High School Teachers program has used WLAP's system to record several physics lectures directed toward a broad audience. And a new project called MScribe, which is essentially the WLAP system coupled with an infrared tracking camera, is being used by the University of Michigan to record several University courses this academic year. All lectures can be viewed on any major platform with any common internet browser...

  20. Nursing students' attitudes to biomedical science lectures.

    Science.gov (United States)

    Al-Modhefer, A K; Roe, S

    To explore what first-year nursing students believe to be the preferred characteristics of common foundation programme biomedical science lecturers, and to investigate whether students prefer active or passive learning. Survey and interview methodologies were used to explore the attitudes of a cohort of first-year nursing students at Queen's University Belfast. Questionnaires were distributed among 300 students. Individuals were asked to select five of a list of 14 criteria that they believed characterised the qualities of an effective lecturer. Informal interviews were carried out with five participants who were randomly selected from the sample to investigate which teaching methods were most beneficial in assisting their learning. Nursing students favoured didactic teaching and found interactivity in lectures intimidating. Students preferred to learn biomedical science passively and depended heavily on their instructors. In response to the survey, the authors propose a set of recommendations to enhance the learning process in large classes. This guidance includes giving clear objectives and requirements to students, encouraging active participation, and sustaining student interest through the use of improved teaching aids and innovative techniques.

  1. Academic Training: Summer Student Lecture Programme

    CERN Multimedia

    2004-01-01

    Main Auditorium, bldg. 500 DATE TIME LECTURER TITLE Monday 12 July 09:15 - 10:00 G. Ross (The Rudolf Peierls Centre for Theoretical Physics & CERN) Fundamental Concepts of Particle Physics (1/6) 10:15 - 11:00 O. Bruening (CERN) Accelerators (1/5) 11:15 - 12:00 L. Di Lella (CERN) Introduction to Particle Physics (4/4) DATE TIME LECTURER TITLE Tuesday 13 July 09:15 - 10:00 G. Ross (The Rudolf Peierls Centre for Theoretical Physics & CERN) Fundamental Concepts of Particle Physics (2/6) 10:15 - 11:00 O. Bruening (CERN) Accelerators (2/5) 11:15 - 12:00 O. Bruening (CERN) G. Ross (The Rudolf Peierls Centre for Theoretical Physics & CERN) Discussion Session DATE TIME LECTURER TITLE Wednesday 14 July 09:15 - 10:00 G. Ross (The Rudolf Peierls Centre for Theoretical Physics & CERN) Fundamental Concepts of Particle Physics (3/6) 10:15 - 11:00 O. Bruening (CERN) Accelerators (3/5) 11:15 - 12:00 O. Bruening (CERN) Accelerators (4/5) 14:00 - ...

  2. Lecture programme The reality of science today

    CERN Multimedia

    2007-01-01

    What are the new challenges and realities facing scientific research? What is its place in society today? To answer these questions, the History and Philosophy of Sciences Unit of Geneva University, in collaboration with ASPERA, the European network for astroparticle physics research, has organised a programme of lectures entitled La réalité de la science d’aujourd’hui, enjeux et défis de la diversité. This series of lectures will provide researchers and members of the public with a snapshot of the state of science today from the perspective of laboratories and institutes, and on subjects such as funding policy and technological and legal impact. The first lecture will be given by science historian Dominique Pestre (EHESS & Centre Koyré, Paris), renowned for his contributions to the analysis of science past and present, and notably one of the authors of the work "History of CERN". He will discuss the modern methods of producing scientific knowledge which have been develop...

  3. Video Lecture Capture Technology Helps Students Study without Affecting Attendance in Large Microbiology Lecture Courses

    Directory of Open Access Journals (Sweden)

    Jennifer Lynn McLean

    2016-12-01

    Full Text Available Recording lectures using video lecture capture software and making them available for students to watch anytime, from anywhere, has become a common practice in many universities across many disciplines. The software has become increasingly easy to use and is commonly provided and maintained by higher education institutions. Several studies have reported that students use lecture capture to enhance their learning and study for assessments, as well as to catch up on material they miss when they cannot attend class due to extenuating circumstances. Furthermore, students with disabilities and students from non-English Speaking Backgrounds (NESB may benefit from being able to watch the video lecture captures at their own pace. Yet, the effect of this technology on class attendance remains a controversial topic and largely unexplored in undergraduate microbiology education. Here, we show that when video lecture captures were available in our large enrollment general microbiology courses, attendance did not decrease. In fact, the majority of students reported that having the videos available did not encourage them to skip class, but rather they used them as a study tool. When we surveyed NESB students and nontraditional students about their attitudes toward this technology, they found it helpful for their learning and for keeping up with the material.

  4. The Trieste Lecture of John Stewart Bell

    Science.gov (United States)

    Bassi, Angelo; Carlo Ghirardi, Gian

    2007-03-01

    Delivered at Trieste on the occasion of the 25th Anniversary of the International Centre for Theoretical Physics, 2 November 1989 The video of this lecture is available here. Please see the PDF for the transcript of the lecture. General remarks by Angelo Bassi and GianCarlo Ghirardi During the autumn of 1989 the International Centre for Theoretical Physics, Trieste, celebrated the 25th anniversary of its creation. Among the many prestigious speakers, who delivered extremely interesting lectures on that occasion, was the late John Stewart Bell. All lectures have been recorded on tape. We succeeded in getting a copy of John's lecture. In the lecture, many of the arguments that John had lucidly stressed in his writings appear once more, but there are also extremely interesting new remarks which, to our knowledge, have not been presented elsewhere. In particular he decided, as pointed out by the very choice of the title of his lecture, to call attention to the fact that the theory presents two types of difficulties, which Dirac classified as first and second class. The former are those connected with the so-called macro-objectification problem, the latter with the divergences characterizing relativistic quantum field theories. Bell describes the precise position of Dirac on these problems and he stresses appropriately how, contrary to Dirac's hopes, the steps which have led to a partial overcoming of the second class difficulties have not helped in any way whatsoever to overcome those of the first class. He then proceeds to analyse the origin and development of the Dynamical Reduction Program and draws attention to the problems that still affect it, in particular that of a consistent relativistic generalization. When the two meetings Are there quantum jumps? and On the present status of Quantum Mechanics were organized in Trieste and Losinj (Croatia), on 5 10 September 2005, it occurred to us that this lecture, which has never been published, might represent an

  5. Assessment of vocal intensity in lecturers depending on acoustic properties of lecture rooms

    Directory of Open Access Journals (Sweden)

    Witold Mikulski

    2015-08-01

    Full Text Available Background: Lombard’s effect increases the level of vocal intensity in the environment, in which noise occurs. This article presents the results of the author’s own study of vocal intensity level and A-weighted sound pressure level of background noise during normal lectures. The aim of the study was to define whether above-mentioned parameters depend on acoustic properties of rooms (classrooms or lecture rooms and to define how many lectors speak with raised voice. Material and Methods: The study was performed in a group of 50 teachers and lecturers in 10 classrooms with cubature of 160–430 m3 and reverberation time of 0.37–1.3 s (group A consisted of 3 rooms which fulfilled, group B consisted of 3 rooms which almost fulfilled and group C consisted of 4 rooms which did not fulfill criteria based on reverberation time (maximum permissible value is 0.6–0.8 s according to PN-B-02151-4:2015. Criteria of raising voice were based on vocal intensity level (maximum value: 65 dB according to EN ISO 9921:2003. The values of above-mentioned parameters were determined from modes of A-weighted sound pressure level distributions during lectures. Results: Great differentiation of vocal intensity level between lectors was found. In classrooms of group A lectors were not using raised voice, in group B – 21%, and in group C – 60% of lectors were using raised voice. Conclusions: It was observed that acoustic properties of classrooms (defined by reverberation time exert their effect on lecturer’s vocal intensity level (i.e., raising voice, which may contribute to the increased risk of vocal tract illnesses. The occurrence of Lombard’s effect in groups of teachers and lecturers, conducting lectures in rooms, was evidenced. Med Pr 2015;66(4:487–496

  6. Cerebral neurotransmission in huntington's disease and wilson's disease; Zerebrale Neurotransmission bei Chorea Huntington und Morbus Wilson

    Energy Technology Data Exchange (ETDEWEB)

    Barthel, H.; Sabri, O. [Klinik und Poliklinik fuer Nuklearmedizin, Univ. Leipzig (Germany)

    2002-09-01

    Huntington's disease and Wilson's disease are hereditary disorders with different neuropsychiatric symptoms. In both cases, these symptoms are mainly attributed to functional alterations of neurons, which are located in the basal ganglia. According deficits have been found by investigating the dopaminergic neurotransmission with different PET and SPECT tracers. For both diseases, these deficits revealed to concordantly involve the pre- and postsynaptic compartment. Apart from the dopaminergic system, more recent studies showed alterations of other neurotransmitter systems, like the serotonergic, GABA-ergic and opioide system. Except for scientific studies, nuclear medicine imaging is not regularly required for primary diagnosis of both disorders. In the case of Huntington's disease, however, imaging can be helpful for differential diagnosis to other diseases with similar initial symptoms and to determine the organic manifestation of the gene defect. In addition, neurotransmitter imaging with radiortracers could gain more relevance in the future in supporting decisions on specific treatments or for therapy monitoring in both diseases. (orig.) [German] Bei der Chorea Huntington und dem Morbus Wilson handelt es sich um erbliche Erkrankungen mit unterschiedlicher neuropsychiatrischer Symptomatik, welche im Wesentlichen auf Funktionsstoerungen von im Basalganglienbereich lokalisierten Neuronen zurueckgefuehrt werden. Untersuchungen der dopaminergen Neurotransmission mit verschiedenen PET- und SPECT-Radiopharmaka ergaben dementsprechende Defizite, welche fuer beide Erkrankungen konkordant das prae- und postsynaptische Kompartment betrafen. Juengere Studien deuten darueber hinaus auf Stoerungen anderer Neurotransmitter-Systeme, wie z.B. des serotonergen, GABAergen und Opioid-Systems, hin. Ausserhalb von wissenschaftlichen Fragestellungen ist die nuklearmedizinische Bildgebung bei beiden Erkrankungen in der Primaerdiagnostik eher selten erforderlich. Im

  7. Doença de Wilson em crianças e adolescentes: diagnóstico e tratamento Wilson's disease in children and adolescents: diagnosis and treatment

    Directory of Open Access Journals (Sweden)

    Stephania de Andrade Sócio

    2010-06-01

    Full Text Available OBJETIVO: Descrever as formas de apresentação, as alterações laboratoriais ao diagnóstico e o tratamento de crianças e adolescentes com doença de Wilson. MÉTODOS: Estudo descritivo e retrospectivo de 17 crianças e adolescentes com doença de Wilson atendidos no Ambulatório de Hepatologia Pediátrica do Hospital das Clínicas da Universidade Federal de Minas Gerais no período de 1985 a 2008. Os dados foram coletados dos prontuários e durante as consultas ambulatoriais. RESULTADOS: A idade ao diagnóstico variou de 2,8 a 15,1 anos, com média de 8,8±0,9 anos. A forma de apresentação predominante foi hepática (53%, seguida por assintomáticos provenientes de triagem familiar. O anel de Kayser-Fleischer foi encontrado em 41% dos pacientes. A ceruloplasmina encontrava-se alterada em 15/17 pacientes e o cobre urinário variou de 24 a 1000mcg/24h (mediana: 184mcg/24h. O tratamento instituído foi a D-penicilamina. Observaram-se efeitos colaterais em cinco crianças, sem necessidade de interrupção ou troca da medicação. As respostas clínica e laboratorial, com níveis normais de aminotransferases, foram evidenciadas em 14 pacientes após mediana de 10,7 meses de tratamento. Três crianças morreram (uma por hepatite fulminante e duas com complicações da insuficiência hepática grave, apesar do tratamento. CONCLUSÕES: A doença de Wilson é rara na faixa etária pediátrica. A forma de apresentação predominante é a hepática. Seu diagnóstico se baseia principalmente em dosagem de ceruloplasmina baixa, cobre livre e cobre em urina de 24 horas elevados, mas exige alto grau de suspeição. Apresenta boa resposta e tolerância ao tratamento medicamentoso.OBJECTIVE: To describe clinical symptoms, laboratory findings at diagnosis and treatment of children and adolescents with Wilson's disease. METHODS: This is a descriptive and retrospective study of a series of 17 children and adolescents with Wilson's disease, assited at the

  8. Exploring Lecturers' Perceptions of Learning Management System: An Empirical Study Based on TAM

    Directory of Open Access Journals (Sweden)

    Wei Wei Goh

    2014-06-01

    Full Text Available With the pervasive take-up and presence of digital technologies, learning management system (LMS is popular for its open accessibility and its interactive nature. Implementation of LMS has become part of the strategic plan in higher education institution to enhance the flexibility in teaching and learning. It is essential to explore the perceptions of users in using the LMS in order to inform stakeholders the positive influencing aspects and improve the negative factors in the future. This study investigates the perception of lecturers in using LMS in term of perceived usefulness and perceived ease of use for teaching purposes. Technology Acceptance Model (TAM is used as the research framework to design the questionnaire. An online questionnaire was created to address the research questions. The results reveal that lecturers do not react positively towards perceived ease of use of Moodle for teaching. Lecturers treat Moodle as content repository and do not fully utilize the interactive features in Moodle. It was found that usability issues, interaction and communication issues had a negative impact on the lecturers' perception.

  9. Bioremediation: Hope/Hype for Environmental Cleanup (LBNL Summer Lecture Series)

    Energy Technology Data Exchange (ETDEWEB)

    Hazen, Terry [LBNL, Ecology Dept

    2007-07-18

    Summer Lecture Series 2007: Terry Hazen, Senior Staff Scientists and Head of the LBNL Ecology Department, discusses when it's best to resort to engineered bioremediation of contaminated sites, and when it's best to rely on natural attenuation. Recent advances have greatly broadened the potential applications for bioremediation. At the same time, scientists' knowledge of biogeochemical processes has advanced and they can better gauge how quickly and completely contaminants can be degraded without human intervention.

  10. Paris-Princeton Lectures on Mathematical Finance

    CERN Document Server

    Carmona, René A; Kohatsu-Higa, Arturo; Lasry, Jean-Michel; Lions, Pierre-Louis; Pham, Huyên; Taflin, Erik

    2007-01-01

    The Paris-Princeton Lectures in Financial Mathematics, of which this is the third volume, will, on an annual basis, publish cutting-edge research in self-contained, expository articles from outstanding - established or upcoming! - specialists. The aim is to produce a series of articles that can serve as an introductory reference for research in the field. It arises as a result of frequent exchanges between the finance and financial mathematics groups in Paris and Princeton. The present volume sets standards with articles by René Carmona, Ivar Ekeland/Erik Taflin, Arturo Kohatsu-Higa, Pierre-Louis Lions/Jean-Michel Lasry, and Hyuên Pham.

  11. Erice Lectures on Black Holes and Attractors

    CERN Document Server

    Ferrara, Sergio; Marrani, A

    2008-01-01

    These lectures give an elementary introduction to the subject of four dimensional black holes (BHs) in supergravity and the Attractor Mechanism in the extremal case. Some thermodynamical properties are discussed and some relevant formulae for the critical points of the BH effective potential are given. The case of Maxwell-Einstein-axion-dilaton (super)gravity is discussed in detail. Analogies among BH entropy and multipartite entanglement of qubits in quantum information theory, as well moduli spaces of extremal BH attractors, are also discussed.

  12. Weak interactions at high energies. [Lectures, review

    Energy Technology Data Exchange (ETDEWEB)

    Ellis, J.

    1978-08-01

    Review lectures are presented on the phenomenological implications of the modern spontaneously broken gauge theories of the weak and electromagnetic interactions, and some observations are made about which high energy experiments probe what aspects of gauge theories. Basic quantum chromodynamics phenomenology is covered including momentum dependent effective quark distributions, the transverse momentum cutoff, search for gluons as sources of hadron jets, the status and prospects for the spectroscopy of fundamental fermions and how fermions may be used to probe aspects of the weak and electromagnetic gauge theory, studies of intermediate vector bosons, and miscellaneous possibilities suggested by gauge theories from the Higgs bosons to speculations about proton decay. 187 references. (JFP)

  13. [Academy Lectures, 2013.09.11] 

    OpenAIRE

    Neidich, Warren

    2013-01-01

    2 hr The idea of artistic research is a hot topic today, especially in our moment of the information economy and intellectual speculation. The problem is that the word research is bound to specific scientific and reductionist connotations that are connected to its specific methodologies which are at odds with the way art is made. In the lecture entitled “Trans-thinking: Artistic Research in the 21st Century” Neidich will use five examples of his own performative art production created in t...

  14. Graphene: materials in the Flatland (Nobel lecture).

    Science.gov (United States)

    Novoselov, Kostya S

    2011-07-25

    Much like the world described in Abbott's "Flatland", graphene is a two-dimensional object. And, as "Flatland" is "A Romance of Many Dimensions", graphene is much more than just a flat crystal. It possesses a number of unusual properties which are often unique or superior to those in other materials. In this brief lecture I would like to explain the reason for my (and many other people's) fascination with this material, and invite the reader to share some of the excitement I've experienced while researching it. Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  15. Nobel Lecture: Graphene: Materials in the Flatland

    Science.gov (United States)

    Novoselov, K. S.

    2011-07-01

    Much like the world described in Abbott’s Flatland, graphene is a two-dimensional object. And, as “Flatland” is “a romance of many dimensions,” graphene is much more than just a flat crystal. It possesses a number of unusual properties which are often unique or superior to those in other materials. In this brief lecture I would like to explain the reason for my (and many other people’s) fascination with this material, and invite the reader to share some of the excitement I’ve experienced while researching it.

  16. How Hugh Hampton Young's treatment of President Woodrow Wilson's urinary retention and urosepsis affected the resolution of World War I.

    Science.gov (United States)

    Fogg, Ryan; Kutikov, Alexander; Uzzo, Robert G; Canter, Daniel

    2011-09-01

    President Woodrow Wilson was never able to gain ratification of the Treaty of Versailles, the peace accord to end World War I. Before he could convince the American people of the importance of ratification, Wilson suffered a stroke followed by life threatening urinary sepsis due to urinary retention, and was treated by the father of modern urology, Hugh Hampton Young. The effects of these health problems are examined in the context of their implications on international affairs. Biographical sources and primary documentation of Wilson's physicians were reviewed to determine the effect of Wilson's stroke on his voiding habits. Hugh Hampton Young's evaluation and decision making is examined in depth. In the fall of 1919 President Wilson was recovering from a stroke. Shortly after the stroke his preexisting voiding dysfunction progressed to urinary retention from which urinary sepsis developed. Hugh Hampton Young advised on Wilson's case and counseled patience over surgery. The President began voiding spontaneously and recovered from sepsis. The illness left him severely weakened and unable to mount an aggressive campaign to persuade the U.S. Senate of the importance of ratifying the Treaty of Versailles. His personal physician, Admiral Cary T. Grayson, stated that the President was mentally never the same after the sepsis. Wilson's voiding dysfunction contributed to his inability to win approval for the Treaty of Versailles and the League of Nations. As a result, the United States returned to a policy of isolationism and Europe plunged into 2 decades of upheaval, leading to World War II. Copyright © 2011 American Urological Association Education and Research, Inc. Published by Elsevier Inc. All rights reserved.

  17. Woodrow Wilson's hidden stroke of 1919: the impact of patient-physician confidentiality on United States foreign policy.

    Science.gov (United States)

    Menger, Richard P; Storey, Christopher M; Guthikonda, Bharat; Missios, Symeon; Nanda, Anil; Cooper, John M

    2015-07-01

    World War I catapulted the United States from traditional isolationism to international involvement in a major European conflict. Woodrow Wilson envisaged a permanent American imprint on democracy in world affairs through participation in the League of Nations. Amid these defining events, Wilson suffered a major ischemic stroke on October 2, 1919, which left him incapacitated. What was probably his fourth and most devastating stroke was diagnosed and treated by his friend and personal physician, Admiral Cary Grayson. Grayson, who had tremendous personal and professional loyalty to Wilson, kept the severity of the stroke hidden from Congress, the American people, and even the president himself. During a cabinet briefing, Grayson formally refused to sign a document of disability and was reluctant to address the subject of presidential succession. Wilson was essentially incapacitated and hemiplegic, yet he remained an active president and all messages were relayed directly through his wife, Edith. Patient-physician confidentiality superseded national security amid the backdrop of friendship and political power on the eve of a pivotal juncture in the history of American foreign policy. It was in part because of the absence of Woodrow Wilson's vocal and unwavering support that the United States did not join the League of Nations and distanced itself from the international stage. The League of Nations would later prove powerless without American support and was unable to thwart the rise and advance of Adolf Hitler. Only after World War II did the United States assume its global leadership role and realize Wilson's visionary, yet contentious, groundwork for a Pax Americana. The authors describe Woodrow Wilson's stroke, the historical implications of his health decline, and its impact on United States foreign policy.

  18. Making Globalisation Work – The 2006 Geary Lecture

    OpenAIRE

    Joseph Stiglitz

    2008-01-01

    This paper was delivered as the Geary Lecture 2006 at the Burlington Hotel, Dublin, Ireland on 30 August. The Geary Lecture is organised each year in honour of Professor R. C. Geary (1896–1963) the first Director of The Economic and Social Research Institute and the most eminent Irish Statistician and Economist of the twentieth century. This lecture was organised in association with Penguin Books and The Irish Times.

  19. A brief description of my lectures on Cosmological Parameters

    Science.gov (United States)

    Chincarini, Guido

    2015-12-01

    A brief description is presented of three lectures given by the author at the Cosmology School in Kielce, Poland, in 2015. The first two lectures (and part of the third) were on the possibility of using the observations of Gamma Ray Bursts to estimate the equation of state. The third lecture was used to illustrate the beginning of the redshift surveys, focussing on research that carried out in the 1970s.

  20. LECTURE CANCELLED - Academic Training Lecture: Implications of LHC Data to New Physics (1/3)

    CERN Multimedia

    2013-01-01

    PLEASE NOTE THAT THIS LECTURE IS CANCELLED by Alex Pomarol Clotet (Universitat Autònoma de Barcelona, Spain). Monday, March 18, 2013 from 11:00 to 12:00 (Europe/Zurich) at CERN ( 4-3-006 - TH Conference Room ) More information here.

  1. The work of lecturing in high school chemistry

    Science.gov (United States)

    Hwang, SungWon; Roth, Wolff-Michael

    2013-09-01

    Lecturing is an important aspect of the culture of science education. Perhaps because of the negative associations constructivist educators make with lecturing, little research has been done concerning the generally invisible aspects of the (embodied, lived) work that is required. Traditional research on science lectures focuses on ideas and (mental) concepts that somehow are "gotten across"; and it is interested in identifying verbal content and visual representations science teachers provide. The purpose of this study is to explicitly describe and theorize the living work of lecturing that produces in a societal arena everything from which students can learn. We use two case studies from the chemistry lectures in a tenth-grade Singapore classroom to exemplify the central role of the performative aspects of lecturing. We articulate and exemplify assertions that (a) corporeal performances differentiate and coordinate the contents of lecturing with its pitch, rhythm, and speech volume, and thereby orient students to specific discourse features of chemistry; and (b) corporeal performances differentiate and coordinate layers of talk with prosody, gestures, and body orientation, and thereby make analogies available to students. We conclude that what is visible in lectures (e.g., scientific discourse, analogies) is always the outcome of the (generally unattended to) corporeal labor including gestures, body orientation, and prosodic features (e.g., shifts in pitch) and that this outcome | labor pair constitutes an appropriate unit of understanding lecturing as societal phenomenon.

  2. What Don’t We Know About Interactive Lectures?

    Directory of Open Access Journals (Sweden)

    Roger Murphy

    2010-11-01

    Full Text Available This article considers aspects of lecturer-student interaction within the context of lectures in higher education. In particular it considers ways in which lectures can involve observable interactions between students and lecturers, and how these sometimes involve novel uses of visualisation supported by modern technologies. It goes on to consider the different ways in which interactive lectures can involve the use of new technologies such as voting systems and SMS messaging from mobile telephones. A full range of types of interactive lectures is reviewed, and the article notes the serious lack of research in existence which can inform thinking about what is a very widely used form of teaching throughout higher education. As well as considering the possible implications for students and lecturers of participating in interactive lectures, this article also goes on to consider ways in which this type of educational situation could be subjected to rigorous research investigations. It is argued that such research needs to focus both on the processes of interactive lectures as well as their impact on student learning outcomes.

  3. Wilson Disease

    Science.gov (United States)

    ... people taking zinc usually do not experience side effects, some people may experience stomach upset. A health care provider ... 738–4929 Email: nddic@info.niddk.nih.gov Internet: ... diseases to people with digestive disorders and to their families, health ...

  4. Wilson's Disease

    Science.gov (United States)

    ... healthy nerves, bones, collagen and the skin pigment melanin. Normally, copper is absorbed from your food, and ... you must inherit one copy of the defective gene from each parent. If you receive only one ...

  5. Wilson Disease

    Science.gov (United States)

    ... things psychosis—when a person loses contact with reality Other Signs and Symptoms Other signs and symptoms ... analysis. A 24-hour urine collection will show increased copper in the urine in most patients who ...

  6. Lecture capturing assisted teaching and learning experience

    Science.gov (United States)

    Chen, Li

    2015-03-01

    When it comes to learning, a deep understanding of the material and a broadband of knowledge are equally important. However, provided limited amount of semester time, instructors often find themselves struggling to reach both aspects at the same time and are often forced to make a choice between the two. On one hand, we would like to spend much time to train our students, with demonstrations, step by step guidance and practice, to develop strong critical thinking skills and problem-solving skills. On the other hand, we also would like to cover a wide range of content topics to broaden our students' understanding. In this presentation, we propose a working scheme that may assist to achieve these two goals at the same time without sacrificing either one. With the help of recorded and pre-recorded lectures and other class materials, it allows instructors to spend more class time to focus on developing critical thinking skills and problem-solving skills, and to apply and connect principle knowledge with real life phenomena. It also allows our students to digest the material at a pace they are comfortable with by watching the recorded lectures over and over. Students now have something as a backup to refer to when they have random mistakes and/or missing spots on their notes, and hence take more ownership of their learning. Advanced technology have offered flexibility of how/when the content can be delivered, and have been assisting towards better teaching and learning strategies.

  7. Academic Training Lectures - QCD for Postgraduates

    CERN Multimedia

    Maureen Prola-Tessaur

    2010-01-01

    by Giulia Zanderighi (University of Oxford) Monday 12 to Friday 16 April 2010 From 11:00 to 12:00 - Main Auditorium, Bldg. 500-1-001 Monday 12 - Modern QCD - Lecture 1 Starting from the QCD Lagrangian we will revisit some basic QCD concepts and derive fundamental properties like gauge invariance and isospin symmetry and will discuss the Feynman rules of the theory. We will then focus on the gauge group of QCD and derive the Casimirs CF and CA and some useful color identities. Tuesday 13 - Modern QCD - Lecture 2 We will start discussing the matter content of the theory and revisit the experimental measurements that led to the discovery of quarks. We will then consider a classic QCD observable, the R-ratio, and use it to illustrate the appearance of UV divergences and the need to renormalize the coupling constant of QCD. We will then discuss asymptotic freedom and confinement. Finally, we will examine a case where soft and collinear infrared divergences appear, will discuss the soft approximation in QCD ...

  8. Unitarity violation at the Wilson-Fisher fixed point in 4-epsilon dimensions

    CERN Document Server

    Hogervorst, Matthijs; van Rees, Balt C

    2016-01-01

    We consider the continuation of free and interacting scalar field theory to non-integer spacetime dimension d. We find that the correlation functions in these theories are necessarily incompatible with unitarity (or with reflection positivity in Euclidean signature). In particular, the theories contain negative norm states unless d is a positive integer. These negative norm states can be obtained via the OPE from simple positive norm operators, and are therefore an integral part of the theory. At the Wilson-Fisher fixed point the non-unitarity leads to the existence of complex anomalous dimensions. We demonstrate that they appear already at leading order in the epsilon expansion.

  9. Tricritical point of lattice QCD with Wilson quarks at finite temperature and density

    Science.gov (United States)

    Luo, Xiang-Qian

    2004-11-01

    First principle study of QCD at finite temperature T and chemical potential μ is essential for understanding a wide range of phenomena from heavy-ion collisions to cosmology and neutron stars. However, in the presence of finite density, the critical behavior lattice gauge theory without species doubling, is unknown. At strong coupling, we examine the phase structure on the (μ,T) plane, using Hamiltonian lattice QCD with Wilson fermions. A tricritical point is found, separating the first and second order chiral phase transitions. Such a tricritical point at finite T has not been found in previous work in the Hamiltonian formalism with Kogut-Susskind fermions or naive fermions.

  10. On the amplitude/Wilson loop duality in N=2 SCQCD

    Directory of Open Access Journals (Sweden)

    Marta Leoni

    2015-07-01

    Full Text Available We compute the four-point amplitude with external adjoint particles in N=2 SCQCD at two loops using N=1 superspace Feynman diagrams, extending the results of arXiv:1406.7283. We consider the diagrammatic difference with the corresponding process of N=4 SYM finding a non-vanishing result, which is a non-trivial function of the kinematic variables. This demonstrates that in N=2 SCQCD, even in the sector with external particles in the vector multiplet, the amplitude/Wilson loop duality is inevitably broken at two loops.

  11. Demonstrating Potential of Cell Therapy for Wilson's Disease with the Long-Evans Cinnamon Rat Model

    OpenAIRE

    Jaber, Fadi Luc; Sharma, Yogeshwar; Gupta, Sanjeev

    2017-01-01

    Wilson's disease (WD) is characterized by the inability to excrete copper (Cu) from the body with progressive tissue injury, especially in liver and brain. The molecular defect in WD concerns mutations in ATP7B gene leading to loss of Cu transport from the hepatocyte to the bile canaliculus. While drugs, e.g., Cu chelators, have been available for several decades, these must be taken lifelong, which can be difficult due to issues of compliance or side effects. Many individuals may require liv...

  12. The practice of history: the Smithsons, Colin St John Wilson, and the writing of architectural history

    Directory of Open Access Journals (Sweden)

    Matthew Wells

    2016-06-01

    Full Text Available The purpose of this paper is to explore the type, form, and methodology of history written by practicing architects following the arrival of kunstgeschichte in Britain. Through an analysis of historical writings by Alison and Peter Smithson, and Colin St John Wilson a series of topics are explored including the relationship between history and practice, the use of different narrative structures, and the qualities that a practicing architect can bring to the study of the past. The paper concludes by emphasising that whilst all history is contemporary history, the association between history and its architect-author was not simplistic but a complex interrelationship of position and intention.

  13. Harold Wilson's Efforts at a Negotiated Settlement of the Vietnam War, 1965-67

    OpenAIRE

    Mizumoto, Yoshihiko

    2005-01-01

    This article aims to provide an account of British Prime\\ud Minister Harold Wilson’s diplomatic attempts to settle the\\ud Vietnam War. There are some previous studies discussing his\\ud initiatives in 1965, but little research focussing on his\\ud continuous trials in the following years. Starting with an\\ud analysis of Wilson’s concept of an Anglo-American ‘division of\\ud function’ in Vietnam, this article then examines Anglo-Soviet\\ud summit meetings in 1966-67 and investigates the Wilson-\\ud...

  14. The 1/2 BPS Wilson loop in ABJM theory at two loops

    OpenAIRE

    Bianchi, Marco S.; Giribet, Gaston Enrique; Leoni Olivera, Matías; Penati, Silvia

    2013-01-01

    We compute the expectation value of the 1/2 BPS circular Wilson loop in ABJM theory at two loops in perturbation theory. The result shows perfect agreement with the prediction from localization and the proposed framing factor. Fil: Bianchi, Marco S.. Institut für Physik. Humboldt-Universität zu Berlin; Alemania; Fil: Giribet, Gaston Enrique. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Física de Bue...

  15. B-physics with N{sub f}=2 Wilson fermions

    Energy Technology Data Exchange (ETDEWEB)

    Bernardoni, F.; Simma, H.; Sommer, R. [John von Neumann-Institut fuer Computing NIC/DESY, Zeuthen (Germany)] [and others

    2013-09-15

    We report the final results of the ALPHA collaboration for some B-physics observables: f{sub B}, f{sub B{sub s}} and m{sub b}. We employ CLS configurations with 2 flavors of O(a) improved Wilson fermions in the sea and pion masses ranging down to 190 MeV. The b-quark is treated in HQET to order 1/m{sub b}. The renormalization, the matching and the improvement were performed non-perturbatively, and three lattice spacings reaching a=0.048 fm are used in the continuum extrapolation.

  16. Screening for Wilson disease in acute liver failure: a comparison of currently available diagnostic tests

    DEFF Research Database (Denmark)

    Korman, J.D.; Volenberg, I.; Balko, J.

    2008-01-01

    Acute liver failure (ALF) due to Wilson disease (WD) is invariably fatal without emergency liver transplantation. Therefore, rapid diagnosis of WD should aid prompt transplant listing. To identify the best method for diagnosis of ALF due to WD (ALF-WD), data and serum were collected from 140 ALF...... patients (16 with WD), 29 with other chronic liver diseases and 17 with treated chronic WD. Ceruloplasmin (Cp) was measured by both oxidase activity and nephelometry and serum copper levels by atomic absorption spectroscopy. In patients with ALF, a serum Cp

  17. High-resolution CT findings in Wilson-Mikity syndrome: a case report

    Energy Technology Data Exchange (ETDEWEB)

    Reittner, P.; Fotter, R.; Tillich, M.; Lindbichler, F. [Division of Paediatric Radiology, University Hospital Graz (Austria); Popper, H. [Department of Pathology, University Hospital Graz (Austria); Reiterer, F. [Department of Paediatrics, University Hospital Graz (Austria)

    1998-09-01

    Wilson-Mikity syndrome (WMS), an uncommon cause of respiratory distress presenting after birth, is radiologically characterised by varying degrees of interstitial thickening and bilateral cyst-like foci of hyperinflation. Aetiology and pathogenesis are still unknown. There are few reports of WMS in the paediatric literature and none describing the features and value of high-resolution CT. The purpose of this report is to describe the radiographic findings and high-resolution CT appearance of WMS and to correlate them with the histopathological findings. (orig.) With 3 figs., 6 refs.

  18. A STUDY OF PREDICTION OF DIFFICULT INTUBATION USING MALLAMPATI AND WILSON SCORE CORRELATING WITH CORMACK LEHANE GRADING

    Directory of Open Access Journals (Sweden)

    Vaishali Chandrashekhar

    2015-06-01

    Full Text Available BACKGROUND : This study was carried out to evaluate usefulness of preoperative Mallampati & Wilson’s score grading as a predictor for difficult laryngoscopy & intubation . AIMS : To determine the accuracy of the modified Mallampati test and Wilson score for predicting difficult tracheal intubation and correlation with Cormack Lehane grading . METHODS : This prospective randomized cross sectional Study carried out in 200 patients , posted for surgical procedure under GA with ETT intubation. Preoperative airway assessment using Mallampati grading (MPG & Wilson score done. Conventional anesthesia t echnique followed. Cormack Lehane grading done at laryngoscopy & correlated with previous scores for each patient. RESULTS : A MPG of I/II was found in 140 patients (70% , while 60 patients (30% were class III/IV. 138 patients (69% had a Wilson score of 0 /1 , while 60(30% had a score of 2/3 and 2 patients (1% scored ≥4. One hundred & eighty patients (90% were classified as Cormack - Lehane grade I/II , while 20 patients (10% were considered grade III/IV. Of the 60 patients with a Wilson score of 2/3 , 6 cas es (10% two attempts were required and in 2 cases (3.3% in spite of more than two attempts intubation proved impossible with the conventional laryngoscope , articulated McCoy blade was used. Two patients with a Wilson score ≥4 were intubated with gum elas tic bougie , using articulated McCoy blade. Overall , out of 200 , in 6 patients (3% two attempts of intubation was required and 4 patients (2% intubation required the use of some kind of gadget other than conventional laryngoscope and more than 2 attempts. The correlation between the Cormack - Lehane classification and the number of endotracheal intubation attempts showed that of the 180 patients with I / II grade , 4 patients (1.3% two attempts were required. Of the 20 patients classified as Cormack - Lehane III/IV , 4 cases (20% intubation proved impossible with conventional technique. This

  19. Report made on behalf of the commission of economic affairs, environment and territory about the proposal of law, adopted in second lecture with modifications by the Senate, relative to the electricity and natural gas regulated tariffs; Rapport fait au nom de la Commission des Affaires Economiques, de l'Environnement et du Territoire sur la proposition de loi, adoptee avec modifications par le Senat en deuxieme lecture, relative aux tarifs reglementes d'electricite et de gaz naturel (n.565)

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2008-01-15

    This text is the conclusion of a long parliamentary procedure with several debates about electricity and natural gas prices, for both individual users and companies. The first article of the proposal of law relative to regulated electricity and gas tariffs, is the only one that remains to be discussed, and concerns the households and the companies with a low power consumption. Examined first at the Senate on October 1, 2007, this proposal of law was debated at the House of Commons on December 11, 2007 and modified for one important point: the possibility for households who have made the choice of a de-regulated energy supplier to change back and benefit again of the regulated tariffs. The adoption of this amendment has led to make some adjustments in the proposal of law which are presented in this document. (J.S.)

  20. Automatic Camera Control System for a Distant Lecture with Videoing a Normal Classroom.

    Science.gov (United States)

    Suganuma, Akira; Nishigori, Shuichiro

    The growth of a communication network technology enables students to take part in a distant lecture. Although many lectures are conducted in universities by using Web contents, normal lectures using a blackboard are still held. The latter style lecture is good for a teacher's dynamic explanation. A way to modify it for a distant lecture is to…

  1. Explaining the Unexplainable: Translated Scientific Explanations (TSE) in Public Physics Lectures

    Science.gov (United States)

    Kapon, Shulamit; Ganiel, Uri; Eylon, Bat Sheva

    2010-01-01

    This paper deals with the features and design of explanations in public physics lectures. It presents the findings from a comparative study of three exemplary public physics lectures, given by practicing physicists who are acknowledged as excellent public lecturers. The study uses three different perspectives: the lecture, the lecturer, and the…

  2. USE OF MULTIPLE RESPONSE QUESTIONS (MRQS DURING LECTURE SESSIONS AS A TOOL TO ENHANCE LEARNING

    Directory of Open Access Journals (Sweden)

    Rosh

    2015-12-01

    Full Text Available INTRODUCTION Lecture classes are time tested solid method of teaching and have lot of advantages and few disadvantages. The main drawback is its unidirectional monotonous nature and many a time students fail to concentrate and understand especially when the sessions are long, and from the students’ point of view, many are boring too. Lecture sessions are still continued because of its various advantages. There are many methods tried to improve efficacy and effectiveness of lecture sessions including reinforcement, questions and discussions. There are many studies incorporating multiple choice questions (MCQs in lecture sessions for this purpose, with positive results. These sessions evoke creative thinking and enhance learning. For this purpose MCQs are to be prepared with care considering the areas to be covered. In order to make lecture classes more impressive, interesting and effective, we tried introducing a short multiple response session in between, along with some rewards for correct responses in terms of study materials. AIMS AND OBJECTIVES To study the impact of incorporation of MRQs during theory sessions to enhance the efficacy of teaching- learning process MATERIAL AND METHODS Study was conducted in a private medical college in Calicut. We surveyed 169 MBBS students initially with questionnaire covering various aspects of a lecture classes in general. For the next 6 months we incorporated MRQs in routine theory classes. Survey was then conducted again on the same group using same questionnaire and the results were compared. Scores were given according to performance, a maximum of 5 per question. RESULTS After 6 months the data showed substantial improvement in the understanding pattern of students. The average score regarding the usefulness increased from 3.57 to 3.91. After the intervention a substantial number agreed that the sessions have become more interesting, the score changed from 2.99 to 3.87. This also increased the

  3. [Jena philosophies of nature around 1800].

    Science.gov (United States)

    Breidbach, O

    2000-01-01

    This paper describes the situation and the outline of positions in philosophy of nature in Jena about 1800, in focusing on research other than the key figures Schelling and Hegel. In 1789, Schelling introduced philosophy of nature into the course program of Jena University. Already in 1800, two young scientists--a mathematician (Fischer) and a physiologist--reacted, announcing lectures on Schellingian topics. But only in late 1802, younger philosophers offered courses on those topics. From 1802 onwards, lectures were announced by Schad, Krause, Henrici, Hegel, Oken and the botanist Schelver. Apart from the Fisher lecture from 1800, the program of these presentations was based on Schellingian principles. Analyses of the ideas of Schad, Krause and Schelver show that, about 1800, philosophy of nature in Jena conserved basic ideas of the early philosophy of nature of Schelling. Thus, philosophy of nature in this period of Jena University seemed to follow just one line of reasoning.

  4. Construction of the international system of Versailles, according to the doctrine of Woodrow Wilson

    Directory of Open Access Journals (Sweden)

    MSc. Albulena Halili

    2011-12-01

    Full Text Available Mapping of the international system after the First World War took place in the Conference of Versailles, where a peace treaty was negotiated to end this war, and would reshape the world order. The key role in negotiating peace was handed to the United States of America, and its President Woodrow Wilson. This paper aims to elaborate the doctrine of US President Wilson, presented through the Fourteen Points, which were the basis for the international system that was created after First World War. Two of Wilson’s Fourteen Points, which are the object of study in this paper, had the most important impact on international relations, thereby transforming into international law principles, respected to this day: the right of the people for self-determination, which led to the destruction of multi-national empires, and the creation of a association of nations, which resulted in the establishment of the League of Nations, a predecessor of United Nations. The methodological approach used in this paper is analytical-theoretical, and is based on contemporary literature. It aims to identify the strong and weak sides of this doctrine, and its influence in the establishment of the Versailles international system, which only lasted twenty years. Conclusions from this paper are that the Fourteen Points not only served for the mapping of the Versailles international system but also for the establishment of preceding international systems. Many of those principles are the foundation of contemporary international relations

  5. The role of calculated non-caeruloplasmin-bound copper in Wilson's disease.

    Science.gov (United States)

    Duncan, Andrew; Yacoubian, Calum; Beetham, Robert; Catchpole, Anthony; Bullock, David

    2017-11-01

    Background US and European guidelines suggest the use of calculated non-caeruloplasmin-bound copper (free copper index) for the diagnosis and management of Wilson's Disease. However, there is concern that the required analytical measurements of caeruloplasmin and copper may not be sufficiently robust at the concentrations usually found. Methods Aliquots of six plasma specimens were sent to laboratories participating in the UK National External Quality Assessment Scheme for copper and caeruloplasmin. The variability of these two reported measurements and the calculated non-caeruloplasmin-bound copper concentrations were compared. The variability of caeruloplasmin reference ranges quoted by laboratories was also investigated. Results No laboratories use the required enzymatic methods in the calculation of non-caeruloplasmin-bound copper. The interlaboratory variations in caeruloplasmin concentrations and calculated non-caeruloplasmin-bound copper concentrations were very considerable so making clinical interpretation unreliable. Wide differences in the caeruloplasmin reference ranges used were also found. Conclusions Such variations of the calculated non-caeruloplasmin-bound copper concentrations and the predominant use of immunological methods for measuring caeruloplasmin preclude a clinical role for this calculated value in the investigation of Wilson's disease.

  6. Wilson's disease: the importance of measuring serum caeruloplasmin non-immunologically.

    Science.gov (United States)

    Walshe, J M

    2003-03-01

    Wilson's disease should be considered as a possible diagnosis in any child, adolescent or young adult with liver damage without other explanation, especially when haemolysis is present. However, it may also present in adolescents or young adults with neurological signs confined to the motor system. The first diagnostic screening test is the estimation of the serum caeruloplasmin and total serum copper concentrations, with calculation of the serum non-caeruloplasmin-bound ('free') copper. Serum caeruloplasmin, which contains copper, is best determined by measurement of its oxidase activity, as the immunonephelometric method measures both caeruloplasmin and the biologically inactive apo-form. Diagnosis may be confirmed by an elevated urinary copper excretion. All close relatives of an identified patient must be screened and, where doubt persists, investigation of the Wilson's gene at chromosome 13q14.3 can be employed. Lifelong follow-up studies are best conducted in a specialist centre. Compliance with chelating therapy (penicillamine or trientine) or administration of the metal antagonist tetrathiomolybdate or zinc is monitored by determination of the serum 'free' copper, which should be maintained at or near 1.6 micromol/L (10 microg/100 mL). Side-effects of therapy are detected by the estimation of urinary total protein, full blood count and erythrocyte sedimentation rate, clotting factors and liver function tests.

  7. [Diagnosis and therapy of inheritable liver diseases: hemochromatisis, Wilson's disease and alpha-1-antitrypsin deficiency].

    Science.gov (United States)

    Strassburg, Ch P

    2005-01-19

    The recent years have seen significant progress in the area of genetically determined liver diseases. For hereditary hemochromatosis, Wilson's disease and alpha-1 antitrypsin deficiency the underlying genetic defects have been described and well characterized. Although a direct relationship between genetic defect and disease manifestation exists genetic test only have a limited diagnostic usefulness which requires exact knowledge of the underlying molecular pathology. The classical C282Y and H63D mutations of the HFE gene only show a penetrance of 10-20% in hemochromatosis and are not useful for population screening. Genetic screening for ATP7B (Wilson's disease) and alpha-1 antitrypsin deficiency variants is limited by the existence of a plethora of individual mutations. Genetic tests are mainly restricted to the counseling of families in whom these diseases are present. Foremost the diagnosis of the three diseases is reached by clinical, biochemical and in some instances also histological means which are supplemented and confirmed by the use of appropriate genetic tests.

  8. D-penicillamine-induced ANA (+) ANCA (+) vasculitis in pediatric patients with Wilson's disease.

    Science.gov (United States)

    Lee, Yeonhee; Lee, Sang Taek; Cho, Heeyeon

    2016-05-01

    Anti-neutrophil cytoplasmic antibodies (ANCA) are associated with systemic vasculitis. The pathophysiology of ANCA-associated vasculitis (AAV) has not been clearly proven, and drug-induced ANCA-associated vasculitis has been reported. Wilson's disease is an inborn error of copper metabolism caused by a mutation in the copper transporting gene ATP7B, and traditional treatment is based on copper chelation with agents such as D-penicillamine. There have been rare reports that prolonged D-penicillamine therapy might cause adverse renal events such as membranous nephropathy and minimal change disease, but it is questionable if D-penicillamine induces ANCA-associated vasculitis. We describe 2 patients with Wilson's disease treated with D-penicillamine who presented with ANCA (+) vasculitis and renal involvement. The 2 patients also showed positive results for antinuclear antibody (ANA). Their kidney biopsy findings were compatible with crescentic/necrotizing glomerulonephritis, pauci-immune type. After diagnosis of AAV, D-penicillamine was stopped. Patients were then treated with plasmapheresis and immunosuppressants, including methylprednisolone pulse therapy and intravenous cyclophosphamide. One patient progressed to end-stage renal disease and the other showed persistent proteinuria. These cases suggest that D-penicillamine may induce ANA (+) ANCA (+) vasculitis with severe renal involvement in pediatric patients, and plasmapheresis combined with immunosuppressant should be considered.

  9. Wilson loops in heavy ion collisions and their calculation in AdS/CFT

    CERN Document Server

    Liu, H; Wiedemann, Urs Achim; Liu, Hong; Rajagopal, Krishna; Wiedemann, Urs Achim

    2007-01-01

    Expectation values of Wilson loops define the nonperturbative properties of the hot medium produced in heavy ion collisions that arise in the analysis of both radiative parton energy loss and quarkonium suppression. We use the AdS/CFT correspondence to calculate the expectation values of such Wilson loops in the strongly coupled plasma of N=4 super Yang-Mills (SYM) theory, allowing for the possibility that the plasma may be moving with some collective flow velocity as is the case in heavy ion collisions. We obtain the N=4 SYM values of the jet quenching parameter $\\hat q$, which describes the energy loss of a hard parton in QCD, and of the velocity-dependence of the quark-antiquark screening length for a moving dipole as a function of the angle between its velocity and its orientation. We show that if the quark-gluon plasma is flowing with velocity v_f at an angle theta with respect to the trajectory of a hard parton, the jet quenching parameter $\\hat q$ is modified by a factor gamma_f(1-v_f cos theta), and s...

  10. Characterization of toxic conditions above Wilson's Creek National Battlefield Park, Missouri

    Science.gov (United States)

    Pulley, T.S.; Nimmo, D.W.R.; Tessari, J.D.

    1998-01-01

    Wilson's Creek has an extensive history of toxicity from both point and nonpoint sources. Seven-day chronic daphnid (Ceriodaphnia dubia) bioassays identified one toxic site in the Wilson's Creek watershed. Procedures for the characterization phase of a Toxicity Identification Evaluation (TIE) were modified for chronic assessment and performed on four water samples from the toxic site. The characterization involved chemical/physical alterations of samples, combined with bioassays, to help in identification of the class(es) of toxicants; followed by chemical analyses. To help understand the additivity of mixtures, toxic units were derived. Successive samples contained concentrations of copper, cadmium, nickel and zinc that literature values describe as being chronically toxic to daphnids. Summed chronic toxic units for these values greatly exceeded ambient toxic units, and more than accounted for observed toxicity. Substantial fluctuations in water quality occurred over the five sampling periods of the characterization studies and a Test of Methods, June through August, 1991. This variability illustrates the difficulty in detecting and documenting nonpoint sources of pollution. Tests using living organisms, in conjunction with toxicity identification methods, on samples taken over time appear to be appropriate for detecting acute and chronic toxicity in areas impacted by intermittent point and nonpoint-source toxicity.

  11. Rheumatic fever in Ireland: the role of Dr Monica Lea Wilson (1889-1971).

    Science.gov (United States)

    Ward, O Conor

    2013-02-01

    In 1869 William Stokes pointed out that the severity of rheumatic fever in Dublin had declined over recent decades. Similar worldwide decline led to the closure of many internationally famous rheumatic fever centres. The discovery by Robert Collis that rheumatic fever was a sequel to haemolytic streptococcal infection and the subsequent discovery of penicillin accelerated the decline. St Gabriel's Hospital in Dublin opened in 1951 under the clinical direction of Dr Monica Lea Wilson. Contrary to contemporary medical opinion a regimen of very prolonged bed rest was enforced. From 1961 the family doctors became concerned at the adverse psychological effects of the unnecessarily prolonged hospital stay. Twenty-seven of the 56 inpatients were re-assessed. None of them showed any evidence of active rheumatic fever and their parents took them home. The hospital closed in 1968. Dr Lea Wilson distanced herself from mainstream medicine and she is best remembered for having presented an unrecognized Caravaggio painting to the Jesuit Order in recognition of their pastoral support at the time of the controversial assassination in 1920 of her husband Percival, an Inspector in the Royal Irish Constabulary.

  12. Spectral properties of the Wilson-Dirac operator and random matrix theory

    Science.gov (United States)

    Kieburg, Mario; Verbaarschot, Jacobus J. M.; Zafeiropoulos, Savvas

    2013-11-01

    Random matrix theory has been successfully applied to lattice quantum chromodynamics. In particular, a great deal of progress has been made on the understanding, numerically as well as analytically, of the spectral properties of the Wilson-Dirac operator. In this paper, we study the infrared spectrum of the Wilson-Dirac operator via random matrix theory including the three leading order a2 correction terms that appear in the corresponding chiral Lagrangian. A derivation of the joint probability density of the eigenvalues is presented. This result is used to calculate the density of the complex eigenvalues, the density of the real eigenvalues, and the distribution of the chiralities over the real eigenvalues. A detailed discussion of these quantities shows how each low-energy constant affects the spectrum. Especially we consider the limit of small and large (which is almost the mean field limit) lattice spacing. Comparisons with Monte Carlo simulations of the random matrix theory show a perfect agreement with the analytical predictions. Furthermore we present some quantities which can be easily used for comparison of lattice data and the analytical results.

  13. Daily survival rate and habitat characteristics of nests of Wilson's Plover

    Science.gov (United States)

    Zinsser, Elizabeth; Sanders, Felicia J.; Gerard, Patrick D.; Jodice, Patrick G.R.

    2017-01-01

    We assessed habitat characteristics and measured daily survival rate of 72 nests of Charadrius wilsonia (Wilson's Plover) during 2012 and 2013 on South Island and Sand Island on the central coast of South Carolina. At both study areas, nest sites were located at slightly higher elevations (i.e., small platforms of sand) relative to randomly selected nearby unused sites, and nests at each study area also appeared to be situated to enhance crypsis and/or vigilance. Daily survival rate (DSR) of nests ranged from 0.969 to 0.988 among study sites and years, and the probability of nest survival ranged from 0.405 to 0.764. Flooding and predation were the most common causes of nest failure at both sites. At South Island, DSR was most strongly related to maximum tide height, which suggests that flooding and overwash may be common causes of nest loss for Wilson's Plovers at these study sites. The difference in model results between the 2 nearby study sites may be partially due to more-frequent flooding at Sand Island because of some underlying yet unmeasured physiographic feature. Remaining data gaps for the species include regional assessments of nest and chick survival and habitat requirements during chick rearing.

  14. Schwarzschild radius from Monte Carlo calculation of the Wilson loop in supersymmetric matrix quantum mechanics.

    Science.gov (United States)

    Hanada, Masanori; Miwa, Akitsugu; Nishimura, Jun; Takeuchi, Shingo

    2009-05-08

    In the string-gauge duality it is important to understand how the space-time geometry is encoded in gauge theory observables. We address this issue in the case of the D0-brane system at finite temperature T. Based on the duality, the temporal Wilson loop W in gauge theory is expected to contain the information of the Schwarzschild radius RSch of the dual black hole geometry as log(W)=RSch/(2pialpha'T). This translates to the power-law behavior log(W)=1.89(T/lambda 1/3)-3/5, where lambda is the 't Hooft coupling constant. We calculate the Wilson loop on the gauge theory side in the strongly coupled regime by performing Monte Carlo simulations of supersymmetric matrix quantum mechanics with 16 supercharges. The results reproduce the expected power-law behavior up to a constant shift, which is explainable as alpha' corrections on the gravity side. Our conclusion also demonstrates manifestly the fuzzball picture of black holes.

  15. Islands as model systems in ecology and evolution: prospects fifty years after MacArthur-Wilson.

    Science.gov (United States)

    Warren, Ben H; Simberloff, Daniel; Ricklefs, Robert E; Aguilée, Robin; Condamine, Fabien L; Gravel, Dominique; Morlon, Hélène; Mouquet, Nicolas; Rosindell, James; Casquet, Juliane; Conti, Elena; Cornuault, Josselin; Fernández-Palacios, José María; Hengl, Tomislav; Norder, Sietze J; Rijsdijk, Kenneth F; Sanmartín, Isabel; Strasberg, Dominique; Triantis, Kostas A; Valente, Luis M; Whittaker, Robert J; Gillespie, Rosemary G; Emerson, Brent C; Thébaud, Christophe

    2015-02-01

    The study of islands as model systems has played an important role in the development of evolutionary and ecological theory. The 50th anniversary of MacArthur and Wilson's (December 1963) article, 'An equilibrium theory of insular zoogeography', was a recent milestone for this theme. Since 1963, island systems have provided new insights into the formation of ecological communities. Here, building on such developments, we highlight prospects for research on islands to improve our understanding of the ecology and evolution of communities in general. Throughout, we emphasise how attributes of islands combine to provide unusual research opportunities, the implications of which stretch far beyond islands. Molecular tools and increasing data acquisition now permit re-assessment of some fundamental issues that interested MacArthur and Wilson. These include the formation of ecological networks, species abundance distributions, and the contribution of evolution to community assembly. We also extend our prospects to other fields of ecology and evolution - understanding ecosystem functioning, speciation and diversification - frequently employing assets of oceanic islands in inferring the geographic area within which evolution has occurred, and potential barriers to gene flow. Although island-based theory is continually being enriched, incorporating non-equilibrium dynamics is identified as a major challenge for the future. © 2014 John Wiley & Sons Ltd/CNRS.

  16. The neurotoxicity of iron, copper and manganese in Parkinson's and Wilson's diseases.

    Science.gov (United States)

    Dusek, Petr; Roos, Per M; Litwin, Tomasz; Schneider, Susanne A; Flaten, Trond Peder; Aaseth, Jan

    2015-01-01

    Impaired cellular homeostasis of metals, particularly of Cu, Fe and Mn may trigger neurodegeneration through various mechanisms, notably induction of oxidative stress, promotion of α-synuclein aggregation and fibril formation, activation of microglial cells leading to inflammation and impaired production of metalloproteins. In this article we review available studies concerning Fe, Cu and Mn in Parkinson's disease and Wilson's disease. In Parkinson's disease local dysregulation of iron metabolism in the substantia nigra (SN) seems to be related to neurodegeneration with an increase in SN iron concentration, accompanied by decreased SN Cu and ceruloplasmin concentrations and increased free Cu concentrations and decreased ferroxidase activity in the cerebrospinal fluid. Available data in Wilson's disease suggest that substantial increases in CNS Cu concentrations persist for a long time during chelating treatment and that local accumulation of Fe in certain brain nuclei may occur during the course of the disease. Consequences for chelating treatment strategies are discussed. Copyright © 2014 Elsevier GmbH. All rights reserved.

  17. On the large N limit, Wilson Loops, Confinement and Composite Antisymmetric Tensor Field theories

    CERN Document Server

    Castro, C

    2004-01-01

    A novel approach to evaluate the Wilson loops asociated with a $ SU ( \\infty )$ gauge theory in terms of pure string degrees of freedom is presented. It is based on the Guendelman-Nissimov-Pacheva formulation of composite antisymmetric tensor field theories of area (volume ) preserving diffeomorphisms which admit $p$-brane solutions and which provide a $new$ route to scale symmetry breaking and confinement in Yang-Mills theory. The quantum effects are discussed and we evaluate the vacuum expectation values (vev) of the Wilson loops in the large $N$ limit of the $quenched$ reduced $SU(N)$ Yang-Mills theory in terms of a path integral involving pure string degrees of freedom. The $quenched$ approximation is necessary to avoid a crumpling of the string world-sheet giving rise to very large Hausdorff dimensions as pointed out by Olesen. The approach is also consistent with the recent results based on the AdS/CFT correspondence and dual QCD models (dual Higgs model with dual Dirac strings ). More general Loop wav...

  18. Theological presuppositions of the evolutionary epic: From Robert Chambers to E. O. Wilson.

    Science.gov (United States)

    Megill, Allan

    2016-08-01

    We can trace the "evolutionary epic" (named by E. O. Wilson, 1978) back to earlier writers, beginning with Robert Chambers (1844). Its basic elements are: fixation on seeing human history as rooted in biology; an aspiration toward telling the whole history of humankind (in its essential features); and insistence on the overall coherence of the projected narrative. The claim to coherence depends on assuming either that the universe possesses an "embedded rationality," or that it is guided by divine purpose. This article proposes the term "idealism" to refer to these two assumptions taken together, for in practice they were closely linked. Nietzsche (1881) was perhaps the first thinker to point out the evolutionary epic's dependence on such an idealism, and he also pointed out that the assumptions of embedded rationality and of divine purpose are closely connected. Darwin's theory of descent with modification (1859) was sharply inconsistent with these assumptions: he was not an "idealist" in the sense indicated here, and not a proponent of the evolutionary epic. Proclaiming his "materialism," Wilson (1978) failed to acknowledge that the epic depends on idealist assumptions; other adherents of the genre (M. Dowd, L. Rue) resurrect (knowingly or not) its theological roots. Copyright © 2015 Elsevier Ltd. All rights reserved.

  19. Direct determination of Wilson coefficients using $B^0\\to K^{*0}\\mu^+\\mu^-$ decays arXiv

    CERN Document Server

    Hurth, T.; Mahmoudi, F.

    A method to directly determine the Wilson coefficients for rare $b\\to s$ transitions using $B^0\\to K^{*0}\\mu^+\\mu^-$ decays in an unbinned maximum likelihood fit is presented. The method has several advantages compared to the conventional determination of the Wilson coefficients from angular observables that are determined in bins of $q^2$, the square of the mass of the dimuon system. The method uses all experimental information in an optimal way and automatically accounts for experimental correlations. Performing pseudoexperiments, we show the improved sensitivity of the proposed method for the Wilson coefficients. We also demonstrate that it will be possible to use the method with the combined Run 1 and 2 data sample taken by the LHCb experiment.

  20. Local anomaly cancellation in heterotic E{sub 8} x E{sub 8} orbifold compactifications with Wilson line backgrounds

    Energy Technology Data Exchange (ETDEWEB)

    Walter, M.G.A.

    2004-02-01

    We consider several examples of a special class of heterotic compactifications, i.e. heterotic E{sub 8} x E{sub 8} orbifolds with Wilson line backgrounds. By developing a local perspective we show that a brane world like picture emerges. As an important result we prove that the local massless spectrum at such a brane can always be traced back to the global spectrum of a (different) orbifold without Wilson lines. One particular implication of this result is that the use of (discrete) Wilson lines for the construction of phenomenologically interesting models has to be rethought. We show that stringy constraints render the brane spectra consistent. Using our local picture we are able to compute the local anomalies appearing at the different branes for our examples and show that they can all be cancelled by a local version of the Green-Schwarz mechanism at the same time. (orig.)