WorldWideScience

Sample records for wave response analyses

  1. Wave response analyses of floating crane structure; Crane sen no jobu kozobutsu no haro oto

    Energy Technology Data Exchange (ETDEWEB)

    Nobukawa, H.; Takaki, M.; Kitamura, M.; Ahou, G. [Hiroshima University, Hiroshima (Japan). Faculty of Engineering; Higashimura, M. [Fukada Salvage and Marine Works Co. Ltd., Osaka (Japan)

    1996-12-31

    Identifying a dynamic load acting on a lifted load in a floating crane moving in waves is important for preparing an operation manual for the floating crane. Analyses were made on motions in waves of a floating crane with a lifting load of 3,600 tons, with considerations given to deformation of the crane structure. Discussions were given on a dynamic load acting on a lifted load. If a case that considers elastic deformation in the crane structure is compared with a case that does not consider same in calculating hull motions of the floating crane, the difference between them is small if wave length {lambda} to the ship length L is about 0.5. However, if {lambda}/L is 1.0 and 1.5, the difference grows very large. Therefore, the effect of deformation in the crane structure on hull motions of the floating crane cannot be ignored in these cases. A dynamic load acting on a lifted load that considers deformation in the crane structure is about 5% of lifted weight in a headsea condition in which the wave height is 2 m and {lambda}/L is 1.5. As opposed, an estimated value of a dynamic load when the crane structure is regarded as a rigid body is 13%, which is 2.6 times as great as the case that considers deformation of the crane structure. 3 refs., 17 figs., 1 tab.

  2. ANALYSE OF PULSE WAVE PROPAGATION IN ARTERIES

    Institute of Scientific and Technical Information of China (English)

    PAN Yi-shan; JIA Xiao-bo; CUI Chang-kui; XIAO Xiao-chun

    2006-01-01

    Based upon the blood vessel of being regarded as the elasticity tube, and that the tissue restricts the blood vessel wall, the rule of pulse wave propagation in blood vessel was studied. The viscosity of blood, the elastic modulus of blood vessel, the radius of tube that influenced the pulse wave propagation were analyzed. Comparing the result that considered the viscosity of blood with another result that did not consider the viscosity of blood, we finally discover that the viscosity of blood that influences the pulse wave propagation can not be neglected; and with the accretion of the elastic modulus the speed of propagation augments and the press value of blood stream heightens; when diameter of blood vessel reduces, the press of blood stream also heightens and the speed of pulse wave also augments. These results will contribute to making use of the information of pulse wave to analyse and auxiliarily diagnose some causes of human disease.

  3. Analyses of Current And Wave Forces on Velocity Caps

    DEFF Research Database (Denmark)

    Christensen, Erik Damgaard; Buhrkall, Jeppe; Eskesen, Mark C. D.

    2015-01-01

    ) this paper investigates the current and wave forces on the velocity cap and the vertical cylinder. The Morison’s force model was used in the analyses of the extracted force time series in from the CFD model. Further the distribution of the inlet velocities around the velocity cap was also analyzed in detail...

  4. Wave kinematics and response of slender offshore structures. Vol 5: Wave forces and responses

    Energy Technology Data Exchange (ETDEWEB)

    Pedersen, L.M.; Riber, H.J.

    1999-08-01

    A load measuring system (LMS) and a wave measuring system (WMS) has been used on the North Sea platform Tyra. The LMS consists of an instrumented pipe placed vertically in the crest zone of high and steep waves. The WMS consists of an unique sonar system placed on the sea floor. Simultaneous measurements are carried out of the kinematics of waves and currents and the response of the instrumented pipe during a period of five month in the winter 1994/95. Numerical calculations with LIC22 are carried out of the response of the LMS applying the measured wave and current kinematics. The responses are compared to the measured responses of the LMS. The comparison is based on the statistical main properties of the calculated and measured response as the kinematic field is measured 150 metres away from the instrumented pipe. From the analyses the main parameters (reduced velocity V{sub R} and correlation length l{sub c}) for vortex induced vibrations (VIV) are calibrated and the main environmental conditions for VIV are determined. The hydrodynamic coefficients determining the wave and current forces on slender structures are studied (drag coefficient C{sub D} and added mass coefficient C{sub M}). Further, the effect on the drag coefficient due to air blending in the upper part of the wave is determined. (au)

  5. Springing Response Due to Directional Wave Field Excitation

    DEFF Research Database (Denmark)

    Vidic-Perunovic, Jelena; Jensen, Jørgen Juncher

    2004-01-01

    This paper analyses the wave-induced high-frequency bending moment response of ships, denoted springing. The aim is to predict measured severe springing responses in a large bulk carrier. It is shown that the most important springing contribution is due to the resultant second order excitation...... in multidirectional sea. The incident pressure field from the second order bidirectional wave field is derived, including the non-linear cross-coupling terms between the two wave systems (e.g. wind driven waves and swell). The resulting effect of the super-harmonic cross-coupling interaction terms on the springing...... response is discussed. An example with opposing waves is given, representing probably the 'worst' case for energy exchange between the wave systems. Theoretical predictions of standard deviation of wave- and springing-induced stress amidships are compared with full-scale measurements for a bulk carrier....

  6. Wavelet analyses for stress wave detection of piles

    Institute of Scientific and Technical Information of China (English)

    WANG; Jingtao; (王靖涛)

    2003-01-01

    The theoretical foundation for application of wavelet analysis to pile integrity detection has been presented. The mechanism of spectral variations of reflected pulse from various defects in piles is explained by using the wave scattering theory. The theoretical analyses have been verified through the tests of model piles and a lot of engineering piles. A quantitative evaluation method for estimating damage degree of piles is proposed. The characteristic indexes describing spectrum variations of reflected signals and their critical values are given. They can be used not only to evaluate the damage degree but also to identify the kinds of pile defects.

  7. Analyses of Current And Wave Forces on Velocity Caps

    DEFF Research Database (Denmark)

    Christensen, Erik Damgaard; Buhrkall, Jeppe; Eskesen, Mark C. D.;

    2015-01-01

    Velocity caps are often used in connection with for instance offshore intake sea water for the use of for cooling water for power plants or as a source for desalinization plants. The intakes can also be used for river intakes. The velocity cap is placed on top of a vertical pipe. The vertical pipe......) this paper investigates the current and wave forces on the velocity cap and the vertical cylinder. The Morison’s force model was used in the analyses of the extracted force time series in from the CFD model. Further the distribution of the inlet velocities around the velocity cap was also analyzed in detail...

  8. Analysing students’ response times with classroom response systems

    OpenAIRE

    2016-01-01

    Classroom response systems (‘clickers’ etc.) are well documented as having potential for developing knowledge and engagement in the classroom, so much so that they are ubiquitous, almost passé. The wealth of data gathered from such systems is beginning to be analysed and recent work in the peer instruction community (e.g. Miller et. al, 2014) suggests that in some contexts students answering correctly tend to have the shortest (quickest) response times. Recent work at Kingston University ...

  9. Partial wave analyses of antiproton-proton annihilations in flight

    Energy Technology Data Exchange (ETDEWEB)

    Pychy, Julian; Koch, Helmut; Kopf, Bertram; Wiedner, Ulrich [Institut fuer Experimentalphysik I, Ruhr-Universitaet Bochum (Germany)

    2015-07-01

    To investigate important aspects for the upcoming PANDA experiment, partial wave analyses (PWA) of anti pp-annihilation processes are carried out using data from the Crystal Barrel (LEAR) experiment. A coupled channel analysis of the three reactions resulting in the final states K{sup +}K{sup -}π{sup 0}, π{sup 0}π{sup 0}η and π{sup 0}ηη at a beam momentum of 900 MeV/c is currently in progress. Preliminary results on the determination of resonance contributions and of the spin density matrix (SDM) of different light mesons are presented. The elements of the SDM provide important information about the production process. Furthermore, results of the analyses of the channels ωπ{sup 0}, ωπ{sup 0}η and π{sup +}π{sup -}π{sup 0}π{sup 0} are discussed. These studies are focused on the determination of the contributing angular momenta of the anti pp-system as well as of the SDM of the ω meson. Significant spin-alignment effects depending on the production angle are visible here. These results are compared with those for the φ(1020) in the K{sup +}K{sup -}π{sup 0} channel. All analyses have been performed using PAWIAN, a common, object-oriented and easy-to-use PWA software that is being developed at the Ruhr-Universitaet Bochum. This presentation summarizes recent activities of the Crystal Barrel (LEAR) Collaboration.

  10. Rockslide and Impulse Wave Modelling in the Vajont Reservoir by DEM-CFD Analyses

    Science.gov (United States)

    Zhao, T.; Utili, S.; Crosta, G. B.

    2016-06-01

    This paper investigates the generation of hydrodynamic water waves due to rockslides plunging into a water reservoir. Quasi-3D DEM analyses in plane strain by a coupled DEM-CFD code are adopted to simulate the rockslide from its onset to the impact with the still water and the subsequent generation of the wave. The employed numerical tools and upscaling of hydraulic properties allow predicting a physical response in broad agreement with the observations notwithstanding the assumptions and characteristics of the adopted methods. The results obtained by the DEM-CFD coupled approach are compared to those published in the literature and those presented by Crosta et al. (Landslide spreading, impulse waves and modelling of the Vajont rockslide. Rock mechanics, 2014) in a companion paper obtained through an ALE-FEM method. Analyses performed along two cross sections are representative of the limit conditions of the eastern and western slope sectors. The max rockslide average velocity and the water wave velocity reach ca. 22 and 20 m/s, respectively. The maximum computed run up amounts to ca. 120 and 170 m for the eastern and western lobe cross sections, respectively. These values are reasonably similar to those recorded during the event (i.e. ca. 130 and 190 m, respectively). Therefore, the overall study lays out a possible DEM-CFD framework for the modelling of the generation of the hydrodynamic wave due to the impact of a rapid moving rockslide or rock-debris avalanche.

  11. Tropical response to extratropical eastward propagating waves

    Directory of Open Access Journals (Sweden)

    S. Sridharan

    2015-06-01

    Full Text Available Space–time spectral analysis of ERA-interim winds and temperature at 200 hPa for December 2012–February 2013 shows the presence of eastward propagating waves with period near 18 days in mid-latitude meridional winds at 200 hPa. The 18 day waves of k = 1–2 are dominantly present at latitudes greater than 80°, whereas the waves of k = 3–4 are dominant at 60° of both Northern and Southern Hemispheres. Though the 18 day wave of smaller zonal wavenumbers (k = 1–2 are confined to high latitudes, there is an equatorward propagation of the 18 day wave of k = 4 and 5. The wave amplitude of k = 5 is dominant than that of k = 4 at tropical latitudes. In the Northern Hemisphere (NH, there is a poleward tilt in the phase of the wave of k = 5 at mid-latitudes, as height increases indicating the baroclinic nature of the wave, whereas in the Southern Hemisphere (SH, the wave has barotropic structure as there is no significant phase variation with height. At the NH subtropics, the wave activity is confined to 500–70 hPa with moderate amplitudes. It is reported for the first time that the wave of similar periodicity (18 day and zonal structure (k = 5 as that of extratropical wave disturbance has been observed in tropical OLR, a proxy for tropical convection. We suggest that the selective response of the tropical wave forcing may be due to the lateral forcing of the eastward propagating extratropical wave of similar periodicity and zonal structure.

  12. Analyses of Aircraft Responses to Atmospheric Turbulence

    NARCIS (Netherlands)

    Van Staveren, W.H.J.J.

    2003-01-01

    The response of aircraft to stochastic atmospheric turbulence plays an important role in aircraft-design (load calculations), Flight Control System (FCS) design and flight-simulation (handling qualities research and pilot training). In order to simulate these aircraft responses, an accurate

  13. Analyses of Aircraft Responses to Atmospheric Turbulence

    NARCIS (Netherlands)

    Van Staveren, W.H.J.J.

    2003-01-01

    The response of aircraft to stochastic atmospheric turbulence plays an important role in aircraft-design (load calculations), Flight Control System (FCS) design and flight-simulation (handling qualities research and pilot training). In order to simulate these aircraft responses, an accurate mathemat

  14. Analyses of Aircraft Responses to Atmospheric Turbulence

    OpenAIRE

    Van Staveren, W.H.J.J.

    2003-01-01

    The response of aircraft to stochastic atmospheric turbulence plays an important role in aircraft-design (load calculations), Flight Control System (FCS) design and flight-simulation (handling qualities research and pilot training). In order to simulate these aircraft responses, an accurate mathematical model is required. Two classical models will be discussed in this thesis, that is the Delft University of Technology (DUT) model and the Four Point Aircraft (FPA) model. Although they are well...

  15. The response of interferometric gravitational wave detectors

    CERN Document Server

    Finn, Lee Samuel

    2008-01-01

    The standard derivation of the response of interferometric gravitational wave detectors makes a series of erroneous approximations regarding the coordinate trajectory of the light and the parameterization of the null geodesic it travels along. These errors appear to have remained unrecognized for at least thirty five years. We provide, in full detail, a correct derivation of the response of a single-bounce Michelson interferometer to gravitational waves, compare it to the "standard", but incorrect, derivation, and show where the earlier mistakes were made. By a fortuitous set of circumstances, not generally so, the final result is the same.

  16. Assessment of a geological model by surface wave analyses

    Science.gov (United States)

    Martorana, R.; Capizzi, P.; Avellone, G.; D'Alessandro, A.; Siragusa, R.; Luzio, D.

    2017-02-01

    A set of horizontal to vertical spectral ratio (HVSR) and multichannel analysis of surface waves (MASW) measurements, carried out in the Altavilla Milicia (Sicily) area, is analyzed to test a geological model of the area. Statistical techniques have been used in different stages of the data analysis, to optimize the reliability of the information extracted from geophysical measurements. In particular, cluster analysis algorithms have been implemented to select the time windows of the microseismic signal to be used for calculating the spectral ratio H/V and to identify sets of spectral ratio peaks likely caused by the same underground structures. Using results of reflection seismic lines, typical values of P-wave and S-wave velocity were estimated for each geological formation present in the area. These were used to narrow down the research space of parameters for the HVSR interpretation. MASW profiles have been carried out close to each HVSR measuring point, provided the parameters of the shallower layers for the HVSR models. MASW inversion has been constrained by extrapolating thicknesses from a known stratigraphic sequence. Preliminary 1D seismic models were obtained by adding deeper layers to models that resulted from MASW inversion. These justify the peaks of the HVSR curves due to layers deeper than MASW investigation depth. Furthermore, much deeper layers were included in the HVSR model, as suggested by geological setting and stratigraphic sequence. This choice was made considering that these latter layers do not generate other HVSR peaks and do not significantly affect the misfit. The starting models have been used to limit the starting research space for a more accurate interpretation, made considering the noise as a superposition of Rayleigh and Love waves. Results allowed to recognize four main seismic layers and to associate them to the main stratigraphic successions. The lateral correlation of seismic velocity models, joined with tectonic evidences

  17. Wave kinematics and response of slender offshore structures. Vol 4: Wave kinematics

    Energy Technology Data Exchange (ETDEWEB)

    Riber, H.J.

    1999-08-01

    The kinematics of large surface waves has been measured by means of sonar's placed on the sea floor at the Tyra field. Measurements from the most severe storm are analysed and extreme wave velocity profiles are compared to Stoke wave velocity profiles. Statistical distributions of crest velocity and wave celerity are presented. The analysis shows how the deviation from the Stokes prediction varies with wave heights and steepness. Analyses of the directional wave field leads to the conclusion that the extreme waves are three-dimensional. It is shown that the peculiar kinematics of extreme waves is of great relevance to the design of jacket type structures. (au)

  18. Coupled Mooring Analyses for the WEC-Sim Wave Energy Converter Design Tool: Preprint

    Energy Technology Data Exchange (ETDEWEB)

    Sirnivas, Senu; Yu, Yi-Hsiang; Hall, Matthew; Bosma, Bret

    2016-07-01

    A wave-energy-converter-specific time-domain modeling method (WEC-Sim) was coupled with a lumped-mass-based mooring model (MoorDyn) to improve its mooring dynamics modeling capability. This paper presents a verification and validation study on the coupled numerical method. First, a coupled model was built to simulate a 1/25 model scale floating power system connected to a traditional three-point catenary mooring with an angle of 120 between the lines. The body response and the tension force on the mooring lines at the fairlead in decay tests and under regular and irregular waves were examined. To validate and verify the coupled numerical method, the simulation results were compared to the measurements from a wave tank test and a commercial code (OrcaFlex). Second, a coupled model was built to simulate a two-body point absorber system with a chain-connected catenary system. The influence of the mooring connection on the point absorber was investigated. Overall, the study showed that the coupling of WEC-Sim and the MoorDyn model works reasonably well for simulating a floating system with practical mooring designs and predicting the corresponding dynamic loads on the mooring lines. Further analyses on improving coupling efficiency and the feasibility of applying the numerical method to simulate WEC systems with more complex mooring configuration are still needed.

  19. Coupled Mooring Analyses for the WEC-Sim Wave Energy Converter Design Tool

    Energy Technology Data Exchange (ETDEWEB)

    Sirnivas, Senu; Yu, Yi-Hsiang; Hall, Matthew; Bosma, Bret

    2016-06-24

    A wave-energy-converter-specific time-domain modeling method (WEC-Sim) was coupled with a lumped-mass-based mooring model (MoorDyn) to improve its mooring dynamics modeling capability. This paper presents a verification and validation study on the coupled numerical method. First, a coupled model was built to simulate a 1/25 model scale floating power system connected to a traditional three-point catenary mooring with an angle of 120 between the lines. The body response and the tension force on the mooring lines at the fairlead in decay tests and under regular and irregular waves were examined. To validate and verify the coupled numerical method, the simulation results were compared to the measurements from a wave tank test and a commercial code (OrcaFlex). Second, a coupled model was built to simulate a two-body point absorber system with a chain-connected catenary system. The influence of the mooring connection on the point absorber was investigated. Overall, the study showed that the coupling of WEC-Sim and the MoorDyn model works reasonably well for simulating a floating system with practical mooring designs and predicting the corresponding dynamic loads on the mooring lines. Further analyses on improving coupling efficiency and the feasibility of applying the numerical method to simulate WEC systems with more complex mooring configuration are still needed.

  20. Swash Zone Response under Various Wave Regimes

    DEFF Research Database (Denmark)

    Vicinanza, Diego; Baldock, Tom; Contestabile, Pasquale

    2011-01-01

    The modelling of swash zone (SZ) sediment transport and the resulting morphodynamics have been areas of active research over the last decade. However, many details are still to be understood, whose knowledge will be greatly advanced by the collection of high-quality data under the controlled large......-scale laboratory conditions. The research describes tests carried out in the large wave flume of the Maritime Engineering Laboratory at Catalonia University of Technology, to investigate the SZ under the storm conditions. Its main aim was to compare beach-profile responses for monochromatic waves, monochromatic...

  1. Kinetic full wave analyses of O-X-B mode conversion of EC waves in tokamak plasmas

    Science.gov (United States)

    Fukuyama, Atsushi; Khan, Shabbir Ahmad; Igami, Hiroe; Idei, Hiroshi

    2016-10-01

    For heating and current drive in a high-density plasma of tokamak, especially spherical tokamak, the use of electron Bernstein waves and the O-X-B mode conversion were proposed and experimental observations have been reported. In order to evaluate the power deposition profile and the current drive efficiency, kinetic full wave analysis using an integral form of dielectric tensor has been developed. The incident angle dependence of wave structure and O-X-B mode conversion efficiency is examined using one-dimensional analysis in the major radius direction. Two-dimensional analyses on the horizontal plane and the poloidal plane are also conducted, and the wave structure and the power deposition profile are compared with those of previous analyses using ray tracing method and cold plasma approximation. This work is supported by JSPS KAKENHI Grant Number JP26630471.

  2. Lamb Wave Response of Fatigued Composite Samples

    Science.gov (United States)

    Seale, Michael; Smith, Barry T.; Prosser, William H.; Masters, John E.

    1994-01-01

    Composite materials are being more widely used today by aerospace, automotive, sports equipment, and a number of other commercial industries because of their advantages over conventional metals. Composites have a high strength-to-weight ratio and can be constructed to meet specific design needs. Composite structures are already in use in secondary parts of the Douglas MD-11 and are planned to be used in the new MD-12X. Plans also exist for their use in primary and secondary structures on the Boeing 777. Douglas proposed MD-XX may also incorporate composite materials into primary structures such as the wings and tail. Use of composites in these structures offers weight savings, corrosion resistance, and improved aerodynamics. Additionally, composites have been used to repair cracks in many B-1Bs where traditional repair techniques were not very effective. Plans have also been made to reinforce all of the remaining B-1s with composite materials. Verification of the structural integrity of composite components is needed to insure safe operation of these aerospace vehicles. One aspect of the use of these composites is their response to fatigue. To track this progression of fatigue in aerospace structures, a convenient method to nondestructively monitor this damage needs to be developed. Traditional NDE techniques used on metals are not easily adaptable to composites due to the inhomogeneous and anisotropic nature of these materials. Finding an effective means of nondestructively monitoring fatigue damage is extremely important to the safety and reliability of such structures. Lamb waves offer one method of evaluating these composite materials. As a material is fatigued, the modulus degrades. Since the Lamb wave velocity can be related to the modulus of the material, an effective tool can be developed to monitor fatigue damage in composites by measuring the velocity of these waves. In this work, preliminary studies have been conducted which monitor fatigue damage in

  3. Correlations of $\\boldsymbol{\\pi N}$ Partial Waves for Multi-Reaction Analyses

    CERN Document Server

    Döring, M; Rönchen, D; Workman, R

    2016-01-01

    In the search for missing baryonic resonances, many analyses include data from a variety of pion- and photon-induced reactions. For elastic $\\pi N$ scattering, however, usually the partial waves of the SAID or other groups are fitted, instead of data. We provide the partial-wave covariance matrices needed to perform correlated $\\chi^2$ fits, in which the obtained $\\chi^2$ equals the actual $\\chi^2$ up non-linear and normalization corrections. For any analysis relying on partial waves extracted from elastic pion scattering, this is a prerequisite to assess the significance of resonance signals and to assign any uncertainty on results. The influence of systematic errors is also considered.

  4. Antiplane response of isosceles triangular hill to incident SH waves

    Institute of Scientific and Technical Information of China (English)

    Qiu Faqiang; Liu Diankui

    2005-01-01

    In this paper, antiplane response of an isosceles triangular hill to incident SH waves is studied based on the method of complex function and by using moving coordinate system. The standing wave function, which can satisfy the governing equation and boundary condition, is provided. Furthermore, numerical examples are presented; the influences of wave number and angle of the incident waves and the angle of the hill's peak on ground motion are discussed.

  5. Spiral Wave Dynamics in a Response System Subjected to a Spiral Wave Forcing

    Institute of Scientific and Technical Information of China (English)

    LI Guang-Zhao; CHEN Yong-Qi; TANG Guo-Ning; LIU Jun-Xian

    2011-01-01

    @@ Unidirectional linear error feedback coupling of two excitable medium systems displaying spiral waves is considered.The spiral wave in the response system is thus subjected to a spiral wave forcing.We find that the unidirectional feedback coupling can lead to richer behaviour than the mutual coupling.The spiral wave dynamics in the response system depends on the coupling strength and frequency mismatch.When the coupling strength is small, the feedback coupling induces the drift or meander of the forced spiral wave.When the coupling strength is large enough, the feedback coupling may lead to the transition from spiral wave to anti-target or target-like wave.The generation of anti-target wave in coupled excitable media is observed for the first time.Furthermore, when the coupling strength is strong, the synchronization between two subsystems can be established.%Unidirectional linear error feedback coupling of two excitable medium systems displaying spiral waves is considered. The spiral wave in the response system is thus subjected to a spiral wave forcing. We find that the unidirectional feedback coupling can lead to richer behaviour than the mutual coupling. The spiral wave dynamics in the response system depends on the coupling strength and frequency mismatch. When the coupling strength is small, the feedback coupling induces the drift or meander of the forced spiral wave. When the coupling strength is large enough, the feedback coupling may lead to the transition from spiral wave to anti-target or target-like wave. The generation of anti-target wave in coupled excitable media is observed for the first time. Furthermore,when the coupling strength is strong, the synchronization between two subsystems can be established.

  6. Analyses of embedded wave properties in the CINDY2011/DYNAMO MJO case produced by NICAM.

    Science.gov (United States)

    Miyakawa, T.; Kikuchi, K.

    2015-12-01

    The Madden-Julian Oscillation (MJO) materialize as a complex of tropical waves. It is controversial whether the waves are principally passive responses to the latent heat released by the massive convective envelope, or the wave-dynamics are the essential pillars of the mechanics of the MJO. Either way, it is of interest to identify the respective contributions from various waves in a MJO convective envelope. The combined-Fourier-wavelet-transform technique introduced by Kikuchi (2014) enables us to dissolve the MJO convective envelope into different tropical-wave components and quantify their contributions, at any given time and location. We applied this technique to the outward longwave radiation data observed during the CINDY2011 campaign, as well as to those simulated (Miyakawa et al. 2014) by the global cloud-system resolving model NICAM on the K computer. The MJOs in the model were able to propagate eastward at a similar speed with observation although they underestimated the strong Kelvin-wave signals embedded in the observed MJO, supporting that the waves are principally passive responses to the MJO-scale environment. On the other hand, the MJO eastward propagation was delayed in a simulation that overestimated westward cyclonic disturbances and associated surface latent heat flux near the equator, suggesting that the disturbances embedded in the MJO convective envelope can feedback to the MJO-scale features under certain conditions. Kikuchi, K., 2014: An introduction to combined Fourier-wavelet transform and its application to convectively coupled equatorial waves. Clim. Dyn., 43, 1339-1356. Miyakawa, T., et al. 2014: Madden-Julian Oscillation prediction skill of a new-generation global model, Nature Commun., 5, 3769, doi:10.1038/ncomms4769.

  7. Gravitational wave detector response in terms of spacetime Riemann curvature

    CERN Document Server

    Koop, Michael J

    2013-01-01

    Gravitational wave detectors are typically described as responding to gravitational wave metric perturbations, which are gauge-dependent and --- correspondingly --- unphysical quantities. This is particularly true for ground-based interferometric detectors, like LIGO, space-based detectors, like LISA and its derivatives, spacecraft doppler tracking detectors, and pulsar timing arrays detectors. The description of gravitational waves, and a gravitational wave detector's response, to the unphysical metric perturbation has lead to a proliferation of false analogies and descriptions regarding how these detectors function, and true misunderstandings of the physical character of gravitational waves. Here we provide a fully physical and gauge invariant description of the response of a wide class of gravitational wave detectors in terms of the Riemann curvature, the physical quantity that describes gravitational phenomena in general relativity. In the limit of high frequency gravitational waves, the Riemann curvature...

  8. A Rosetta Stone Relating Conventions In Photo-Meson Partial Wave Analyses

    Energy Technology Data Exchange (ETDEWEB)

    A.M. Sandorfi, B. Dey, A. Sarantsev, L. Tiator, R. Workman

    2012-04-01

    A new generation of complete experiments in pseudoscalar meson photo-production is being pursued at several laboratories. While new data are emerging, there is some confusion regarding definitions of asymmetries and the conventions used in partial wave analyses (PWA). We present expressions for constructing asymmetries as coordinate-system independent ratios of cross sections, along with the names used for these ratios by different PWA groups.

  9. Springing response due to bidirectional wave excitation

    DEFF Research Database (Denmark)

    Vidic-Perunovic, Jelena

    2005-01-01

    theories deal with the unidirectional wave excitation. This is quite standard. The problem is how to include more than one directional wave systems described by a wave spectrum with arbitrary heading. The main objective of the present work has been to account for the additional second-order springing...... a discrepancy with full-scale measurements exists, but worse is that no tendency in the measurement trend is captured. An important source of high frequency springing excitation is undoubtedly missing. The full-scale measurements that are presented in the thesis and have been used for the validation are unique...... because, to the author's knowledge, this is the first time that the wave data were collected simultaneously with stress records on the deck of the ship. This is highly appreciated because one can use the precise input and not only the most probable sea state statistics. The actual picture of the sea waves...

  10. Analyses of demand response in Denmark[Electricity market

    Energy Technology Data Exchange (ETDEWEB)

    Moeller Andersen, F.; Grenaa Jensen, S.; Larsen, Helge V.; Meibom, P.; Ravn, H.; Skytte, K.; Togeby, M.

    2006-10-15

    Due to characteristics of the power system, costs of producing electricity vary considerably over short time intervals. Yet, many consumers do not experience corresponding variations in the price they pay for consuming electricity. The topic of this report is: are consumers willing and able to respond to short-term variations in electricity prices, and if so, what is the social benefit of consumers doing so? Taking Denmark and the Nord Pool market as a case, the report focuses on what is known as short-term consumer flexibility or demand response in the electricity market. With focus on market efficiency, efficient allocation of resources and security of supply, the report describes demand response from a micro-economic perspective and provides empirical observations and case studies. The report aims at evaluating benefits from demand response. However, only elements contributing to an overall value are presented. In addition, the analyses are limited to benefits for society, and costs of obtaining demand response are not considered. (au)

  11. Analyses of demand response in Denmark[Electricity market

    Energy Technology Data Exchange (ETDEWEB)

    Moeller Andersen, F.; Grenaa Jensen, S.; Larsen, Helge V.; Meibom, P.; Ravn, H.; Skytte, K.; Togeby, M.

    2006-10-15

    Due to characteristics of the power system, costs of producing electricity vary considerably over short time intervals. Yet, many consumers do not experience corresponding variations in the price they pay for consuming electricity. The topic of this report is: are consumers willing and able to respond to short-term variations in electricity prices, and if so, what is the social benefit of consumers doing so? Taking Denmark and the Nord Pool market as a case, the report focuses on what is known as short-term consumer flexibility or demand response in the electricity market. With focus on market efficiency, efficient allocation of resources and security of supply, the report describes demand response from a micro-economic perspective and provides empirical observations and case studies. The report aims at evaluating benefits from demand response. However, only elements contributing to an overall value are presented. In addition, the analyses are limited to benefits for society, and costs of obtaining demand response are not considered. (au)

  12. Doppler-cancelled response to VLF gravitational waves

    Science.gov (United States)

    Caporali, A.

    1981-01-01

    The interaction of long periodic gravitational waves with a three link microwave system known as the Doppler Cancelling System is discussed. This system, which was developed for a gravitational redshift experiment, uses one-way and two-way Doppler informatin to construct the beat signal of two reference oscillators moving with respect to each other. The geometric optics approximation is used to derive the frequency shift produced on a light signal propagating in a gravitational wave space-time. The signature left on the Doppler-cancelled beat by burst and continuous gravitational waves is analyzed. A comparison is made between the response to gravitational waves of the Doppler Cancelling System and that of a Doppler tracking system which employs two-way, round-trip radio waves. A three-fold repetition of the gravitational wave form is found to be a common feature of the response functions of both systems. These two functions otherwise exhibit interesting differences.

  13. Evaluation of Hydraulic Response of the Wave Dragon

    DEFF Research Database (Denmark)

    Frigaard, Peter; Kofoed, Jens Peter

    The present study investigates the hydraulic response of the wave energy converter Wave Dragon. This is done by peforming model tests in a wave tank in the Hydraulics & Coastal Engineering Laboratory at Aalborg University. In the model tests a floating scale model (length scale 1:50) of the Wave...... Dragon is subjected to irregular, long crested irregular and short crested sea conditions corresponding to typical situations under which the Wave Dragon will produce power. Furthermore two situations corresponding to extreme storm conditions are tested. The objective of the study is to determine...... the wave induced forces in the moorings and in the junction between the reflectors and the reservoir part, and motions of the Wave Dragon situated in different sea conditions....

  14. Evaluation of Hydraulic Response of the Wave Dragon

    DEFF Research Database (Denmark)

    Frigaard, Peter; Kofoed, Jens Peter

    The present study investigates the hydraulic response of the wave energy converter Wave Dragon. This is done by peforming model tests in a wave tank in the Hydraulics & Coastal Engineering Laboratory at Aalborg University. In the model tests a floating scale model (length scale 1:50) of the Wave...... Dragon is subjected to irregular, long crested irregular and short crested sea conditions corresponding to typical situations under which the Wave Dragon will produce power. Furthermore two situations corresponding to extreme storm conditions are tested. The objective of the study is to determine...... the wave induced forces in the moorings and in the junction between the reflectors and the reservoir part, and motions of the Wave Dragon situated in different sea conditions....

  15. Dynamic Responses of Truss Spar Due to Wave Actions

    Directory of Open Access Journals (Sweden)

    V.J. Kurian

    2013-01-01

    Full Text Available Spar platforms have been used for drilling, production and storage of oil and gas in the offshore deepwater region. The structure is installed at the deepwater locations in the sea and is exposed to continuous action of wind, wave, current and other environmental forces. Wave force constitutes about 70% of the total environmental force and could be considered as the most significant force affecting the dynamic responses needed for the design of these structures. In this study, the dynamic responses of the truss spar due to wave actions including the wave force theories and wave propagation directions are investigated. Numerical simulations are developed to investigate the accuracy of the wave force theories i.e., Morison equation and Diffraction theory, for large structure such as truss spar. The investigation is further expanded to study responses of the truss spar due to variations directions of the wave propagated. The truss spar is modelled as a rigid body with three degrees of freedom restrained by mooring lines. In the simulation, the mass, damping and stiffness matrices are evaluated at every time step. The equations of motion are formulated for the platform dynamic equilibrium and solved by using Newmark Beta method. To compute the wave force for truss spar, which is large compared to the wave length, Diffraction theory was found to be more appropriate. The Morison equation was found applicable only at the high frequency range. Short crested waves resulted in smaller responses in all the motions than that for long crested waves. Hence, it would be appropriate to consider the short crested wave statistics for the optimum design.

  16. Estimation of waves and ship responses using onboard measurements

    DEFF Research Database (Denmark)

    Montazeri, Najmeh

    of measured ship responses, a parametric description of directional wave spectra (a generalised JONSWAP model) and the transfer functions of the ship responses. The difference between the spectral moments of the measured ship responses and the corresponding theoretically calculated moments formulates a cost...... function. A set of wave parameters, characterising the directional wave spectrum, is estimated through an optimisation problem using global search basin with proper constraints. This approach applies a sequential partitioning procedure, which is able to classify swell and wind sea events using wind...

  17. Fertilization response likelihood for the interpretation of leaf analyses

    Directory of Open Access Journals (Sweden)

    Celsemy Eleutério Maia

    2012-04-01

    Full Text Available Leaf analysis is the chemical evaluation of the nutritional status where the nutrient concentrations found in the tissue reflect the nutritional status of the plants. Thus, a correct interpretation of the results of leaf analysis is fundamental for an effective use of this tool. The purpose of this study was to propose and compare the method of Fertilization Response Likelihood (FRL for interpretation of leaf analysis with that of the Diagnosis and Recommendation Integrated System (DRIS. The database consisted of 157 analyses of the N, P, K, Ca, Mg, S, Cu, Fe, Mn, Zn, and B concentrations in coffee leaves, which were divided into two groups: low yield ( 30 bags ha-1. The DRIS indices were calculated using the method proposed by Jones (1981. The fertilization response likelihood was computed based on the approximation of normal distribution. It was found that the Fertilization Response Likelihood (FRL allowed an evaluation of the nutritional status of coffee trees, coinciding with the DRIS-based diagnoses in 84.96 % of the crops.

  18. Extreme wave and wind response predictions

    DEFF Research Database (Denmark)

    Jensen, Jørgen Juncher; Olsen, Anders S.; Mansour, Alaa E.

    2011-01-01

    The aim of the paper is to advocate effective stochastic procedures, based on the First Order Reliability Method (FORM) and Monte Carlo simulations (MCS), for extreme value predictions related to wave and wind-induced loads.Due to the efficient optimization procedures implemented in standard FORM...

  19. Response of massive bodies to gravitational waves

    CERN Document Server

    Hannibal, L; Hannibal, Ludger; Warkall, Jens

    2000-01-01

    The repsonse of a massive body to gravitational waves is decribed on the microscopic level, taking the metric perturbations of the electromagnetic and gravitational forces into account. The effects found substantially differ from those obtained in the commonly used oscillator model. The electromagnetic coupling induces a dominant surface effect, the gravitational coupling gives rise to the excitation of quadrupole modes, but several oredes of magnitude smaller.

  20. Response of thermal ions to electromagnetic ion cyclotron waves

    Science.gov (United States)

    Anderson, B. J.; Fuselier, S. A.

    1994-01-01

    Electromagnetic ion cyclotron waves generated by 10 - 50 keV protons in the Earth's equatorial magnetosphere will interact with the ambient low-energy ions also found in this region. We examine H(+) and He(+) distribution functions from approx. equals 1 to 160 eV using the Hot Plasma Composition Experiment instrument on AMPTE/CCE to investigate the thermal ion response to the waves. A total of 48 intervals were chosen on the basis of electromagnetic ion cyclotron (EMIC) wave activity: 24 with prevalent EMIC waves and 24 with no EMIC waves observed on the orbit. There is a close correlation between EMIC waves and perpendicular heated ion distributions. For protons the perpendicular temperature increase is modest, about 5 eV, and is always observed at 90 deg pitch angles. This is consistent with a nonresonant interaction near the equator. By contrast, He(+) temperatures during EMIC wave events averaged 35 eV and sometimes exceeded 100 eV, indicating stronger interaction with the waves. Furthermore, heated He(+) ions have X-type distributions with maximum fluxes occurring at pitch angles intermediate between field-aligned and perpendicular directions. The X-type He(+) distributions are consistent with a gyroresonant interaction off the equator. The concentration of He(+) relative to H(+) is found to correlate with EMIC wave activity, but it is suggested that the preferential heating of He(+) accounts for the apparent increase in relative He(+) concentration by increasing the proportion of He(+) detected by the ion instrument.

  1. Response of thermal ions to electromagnetic ion cyclotron waves

    Science.gov (United States)

    Anderson, B. J.; Fuselier, S. A.

    1994-10-01

    Electromagnetic ion cyclotron waves generated by 10 - 50 keV protons in the Earth's equatorial magnetosphere will interact with the ambient low-energy ions also found in this region. We examine H(+) and He(+) distribution functions from approx. equals 1 to 160 eV using the Hot Plasma Composition Experiment instrument on AMPTE/CCE to investigate the thermal ion response to the waves. A total of 48 intervals were chosen on the basis of electromagnetic ion cyclotron (EMIC) wave activity: 24 with prevalent EMIC waves and 24 with no EMIC waves observed on the orbit. There is a close correlation between EMIC waves and perpendicular heated ion distributions. For protons the perpendicular temperature increase is modest, about 5 eV, and is always observed at 90 deg pitch angles. This is consistent with a nonresonant interaction near the equator. By contrast, He(+) temperatures during EMIC wave events averaged 35 eV and sometimes exceeded 100 eV, indicating stronger interaction with the waves. Furthermore, heated He(+) ions have X-type distributions with maximum fluxes occurring at pitch angles intermediate between field-aligned and perpendicular directions. The X-type He(+) distributions are consistent with a gyroresonant interaction off the equator. The concentration of He(+) relative to H(+) is found to correlate with EMIC wave activity, but it is suggested that the preferential heating of He(+) accounts for the apparent increase in relative He(+) concentration by increasing the proportion of He(+) detected by the ion instrument.

  2. Evaluation of hydraulic response of the Wave Dragon

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-02-01

    The present study investigates the hydraulic response of the wave energy converter Wave Dragon. This is done by performing model tests in a wave tank in the Hydraulics and Coastal Engineering Laboratory at Aalborg University. In the model tests a floating scale model (length scale 1:50) of the Wave Dragon is subjected to irregular long crested irregular and short crested sea conditions corresponding to typical situations under which the Wave Dragon will produce power. Furthermore two situations corresponding to extreme storm conditions are tested. The objective of the study is to determine the wave induced forces in the moorings and in the junction between the reflectors and the reservoir part, and motions of the Wave Dragon situated in different sea conditions. On the background of the performed model tests and evaluation of the investigated concept is given. The floating model of Wave Dragon demonstrated a good behaviour and was able to collect water in all sea conditions. Motions in seas with up to 5 m significant wave height were reasonable. Though, the heave motion and the pitch motion seemed to be rather large. wave Dragon survived tests in very severe sea conditions with significant wave heights between 10 m and 15 m. This was the case for long crested waves and short crested as well. Some problems were seen while adjusting the crest freeboard to the different sea conditions. The maximum force in the instrumented junction between the reflector and the reservoir part was found to be approximately 30 MN (3.000 ton). Maximum forces in the mooring system were found to be 20 MN, 30 MN and 140 MN, respectively, giving stresses in the order of 1.000 MPa to 4.000 MPa in the pre-designed wires. (au)

  3. Dioxin: exposure-response analyses and risk assessment.

    Science.gov (United States)

    Steenland, Kyle; Deddens, James

    2003-07-01

    Low-levels of dioxin cause cancer in animals. In 1997 dioxin was found to be a human carcinogen by the International Agency for Research on Cancer, based largely on four studies of industrial workers exposed to high levels. Recently there has been interest in estimating human cancer risk at low level environmental exposures. Here we review quantitative exposure-response analyses and risk assessment for low environmental levels based on the largest existing cohort of workers exposed to dioxin (the U.S. NIOSH cohort). We estimate that doubling background levels of exposure, which may occur for example by eating a lot of fish which have accumulated dioxin, will increase lifetime risk of cancer death by 0.1 to 1.0%. In the US the background risk of cancer death by age 75 is 12%, so doubling background levels of dioxin exposure would increase this lifetime risk to somewhere between 12.1 and 13.0%. Our results agree broadly with results from a German cohort, which is the only other cohort for which a quantitative risk assessment has been conducted.

  4. Fast Evaluation of Ship Responses in Waves

    DEFF Research Database (Denmark)

    Jensen, Jørgen Juncher

    2004-01-01

    The aim of the present paper is to provide a rational and efficient procedure able to predict the design wave-induced motions, accelerations and loads with sufficient engineering accuracy in the conceptual design phase and in risk assessment. The procedure relies only on the following main parame...... parameters of the ship: Length, breadth, draught, block coefficient and water plane area together with the operational profile. The formulas are semi-analytical and the calculations can be easily done using a standard spreadsheet program....

  5. Transient Response Model of Standing Wave Piezoelectric Linear Ultrasonic Motor

    Institute of Scientific and Technical Information of China (English)

    SHI Yunlai; CHEN Chao; ZHAO Chunsheng

    2012-01-01

    A transient response model for describing the starting and stopping characteristics of the standing wave piezoelectric linear ultrasonic motor was presented.Based on the contact dynamic model,the kinetic equation of the motor was derived.The starting and stopping characteristics of the standing wave piezoelectric linear ultrasonic motor according to different loads,contact stiffness and inertia mass were described and analyzed,respectively.To validate the transient response model,a standing wave piezoelectric linear ultrasonic motor based on in-plane modes was used to carry out the simulation and experimental study.The corresponding results showed that the simulation of the motor performances based on the proposed model agreed well with the experimental results.This model will helpful to improve the stepping characteristics and the control flexibility of the standing wave piezoelectric linear ultrasonic motor.

  6. Loads and responses for planing craft in waves

    OpenAIRE

    2004-01-01

    Experimental and numerical analysis of loads and responses for planing craft in waves is considered. Extensive experiments have been performed on a planing craft, in full-scale as well as in model scale. The test set-ups and significant results are reviewed. The required resolution in experiments on planing craft in waves, concerning sampling frequencies, filtering and pressure transducer areas, is investigated. The aspects of peak identification in transient signals, fitting of analytical cu...

  7. Hydroelastic response of a floating runway to cnoidal waves

    Energy Technology Data Exchange (ETDEWEB)

    Ertekin, R. C., E-mail: ertekin@hawaii.edu [Department of Ocean and Resources Engineering, University of Hawaii at Manoa, Honolulu, Hawaii 96822 (United States); Xia, Dingwu [Engineering Services, British Petroleum GoM, Houston, Texas 77079 (United States)

    2014-02-15

    The hydroelastic response of mat-type Very Large Floating Structures (VLFSs) to severe sea conditions, such as tsunamis and hurricanes, must be assessed for safety and survivability. An efficient and robust nonlinear hydroelastic model is required to predict accurately the motion of and the dynamic loads on a VLFS due to such large waves. We develop a nonlinear theory to predict the hydroelastic response of a VLFS in the presence of cnoidal waves and compare the predictions with the linear theory that is also developed here. This hydroelastic problem is formulated by directly coupling the structure with the fluid, by use of the Level I Green-Naghdi theory for the fluid motion and the Kirchhoff thin plate theory for the runway. The coupled fluid structure system, together with the appropriate jump conditions are solved in two-dimensions by the finite-difference method. The numerical model is used to study the nonlinear response of a VLFS to storm waves which are modeled by use of the cnoidal-wave theory. Parametric studies show that the nonlinearity of the waves is very important in accurately predicting the dynamic bending moment and wave run-up on a VLFS in high seas.

  8. STEADY STATE RESPONSE ANALYSIS ON HELICAL SPRING IMPACTED BY SHORT WAVE

    Institute of Scientific and Technical Information of China (English)

    FU Chaoxing; WANG Xiulun; WANG Jirong; LIU Dawei

    2006-01-01

    The wave transmission character of helical spring is applied to establish 2-DOF model of impacted vehicle on the wave impact theory. Considering the concrete structure of helical spring,corresponding responses under different impact frequency of the vehicle are imitated. The reason why the vehicle floor overresponds in some special frequency fields is explored based on analyzing the responses. When the impactions are in low frequency, the change of the spring has not been considered, but this does not affect the results. Because the transmission characters of velocity and acceleration are unanimous in helical spring, the responses characters of velocity and acceleration are also unanimous, the only difference is the magnitude, which can make use of acceleration responses to analyse velocity responses.

  9. Propagation effect of gravitational wave on detector response

    CERN Document Server

    Chang, Zhe; Zhao, Zhi-Chao

    2016-01-01

    The response of a detector to gravitational wave is a function of frequency. When the time a photon moving around in the Fabry-Perot cavities is the same order of the period of a gravitational wave, the phase-difference due to the gravitational wave should be an integral along the path. We present a formula description for detector response to gravitational wave with varied frequencies. The LIGO data for GW150914 and GW 151226 are reexamined in this framework. For GW150924, the traveling time of a photon in the LIGO detector is just a bit larger than a half period of the highest frequency of gravitational wave and the similar result is obtained with LIGO and Virgo collaborations. However, we are not always so luck. In the case of GW151226, the time of a photon traveling in the detector is larger than the period of the highest frequency of gravitational wave and the announced signal cannot match well the template with the initial black hole masses 14.2M$_\\odot$ and 7.5M$_\\odot$.

  10. Response of a Doppler canceling system to plane gravitational waves

    Science.gov (United States)

    Caporali, A.

    1982-01-01

    This paper discusses the interaction of long periodic gravitational waves with a three-link microwave system known as the Doppler canceling system. This system, which was developed for a gravitational red-shift experiment, uses one-way and two-way Doppler information to construct the beat signal of two reference oscillators moving with respect to each other. The geometric-optics approximation is used to derive the frequency shift produced on a light signal propagating in a gravitational-wave space-time. The signature left on the Doppler-cancelled beat by bursts and continuous gravitational waves is analyzed. A comparison is made between the response to gravitational waves of the Doppler canceling system and that of a (NASA) Doppler tracking system which employs two-way, round-trip radio waves. A threefold repetition of the gravitational wave form is found to be a common feature of the response functions of both systems. These two functions otherwise exhibit interesting differences.

  11. Response and energy dissipation of rock under stochastic stress waves

    Institute of Scientific and Technical Information of China (English)

    DENG Jian; BIAN Li

    2007-01-01

    The response and energy dissipation of rock under stochastic stress waves were analyzed based on dynamic fracture criterion of brittle materials integrating with Fourier transform methods of spectral analysis When the stochastic stress waves transnut through rocks,the frequency and energy ratio of harmonic components were calculated by analytical and discrete analysis methods.The stress waves in shale, malmstone and liparite were taken as examples to illustrate the proposed analysis methods.The results show the harder the rock, the less absorption of energy,the more the useless elastic waves transmitting through rock, and the narrower the cutoff frequency to fracture rock.When the whole stress energy doubles either by doubling the duration time or byincreasing the amplitude of stress wave, ratio of the energy of elastic waves transmitting through rock to me whole stress energy (i.e.energy dissipation ratio)is decreased to 10%-15%. When doubling the duration time.the cutoff frequency to fracture rock remains constant.However, with the increase of the amplitude of stress wave. the cutoff frequency increases accordingly.

  12. Numerical Analyses of Caisson Breakwaters on Soft Foundations Under Wave Cyclic Loading

    Institute of Scientific and Technical Information of China (English)

    王元战; 焉振; 王禹迟

    2016-01-01

    A caisson breakwater is built on soft foundations after replacing the upper soft layer with sand. This paper presents a dynamic finite element method to investigate the strength degradation and associated pore pressure development of the intercalated soft layer under wave cyclic loading. By combining the undrained shear strength with the empirical formula of overconsolidation clay produced by unloading and the development model of pore pressure, the dynamic degradation law that describes the undrained shear strength as a function of cycle number and stress level is derived. Based on the proposed dynamic degradation law and M-C yield criterion, a dynamic finite element method is numerically implemented to predict changes in undrained shear strength of the intercalated soft layer by using the general-purpose FEM software ABAQUS, and the accuracy of the method is verified. The effects of cycle number and amplitude of the wave force on the degradation of the undrained shear strength of the intercalated soft layer and the associated excess pore pressure response are investigated by analyzing an overall distribution and three typical sections underneath the breakwater. By comparing the undrained shear strength distributions obtained by the static method and the quasi-static method with the undrained shear strength distributions obtained by the dynamic finite element method in the three typical sections, the superiority of the dynamic finite element method in predicting changes in undrained shear strength is demonstrated.

  13. Numerical analyses of caisson breakwaters on soft foundations under wave cyclic loading

    Science.gov (United States)

    Wang, Yuan-zhan; Yan, Zhen; Wang, Yu-chi

    2016-03-01

    A caisson breakwater is built on soft foundations after replacing the upper soft layer with sand. This paper presents a dynamic finite element method to investigate the strength degradation and associated pore pressure development of the intercalated soft layer under wave cyclic loading. By combining the undrained shear strength with the empirical formula of overconsolidation clay produced by unloading and the development model of pore pressure, the dynamic degradation law that describes the undrained shear strength as a function of cycle number and stress level is derived. Based on the proposed dynamic degradation law and M-C yield criterion, a dynamic finite element method is numerically implemented to predict changes in undrained shear strength of the intercalated soft layer by using the general-purpose FEM software ABAQUS, and the accuracy of the method is verified. The effects of cycle number and amplitude of the wave force on the degradation of the undrained shear strength of the intercalated soft layer and the associated excess pore pressure response are investigated by analyzing an overall distribution and three typical sections underneath the breakwater. By comparing the undrained shear strength distributions obtained by the static method and the quasi-static method with the undrained shear strength distributions obtained by the dynamic finite element method in the three typical sections, the superiority of the dynamic finite element method in predicting changes in undrained shear strength is demonstrated.

  14. Response of thermal ions to electromagnetic ion cyclotron waves

    Energy Technology Data Exchange (ETDEWEB)

    Anderson, B.J. [Johns Hopkins Univ., Laurel, MD (United States); Fuselier, S.A. [Lockheed Palo Alto Research Lab., CA (United States)

    1994-10-01

    Electromagnetic ion cyclotron waves generated by 10-50 keV protons in the Earth`s equatorial magnetosphere will interact with the ambient low-energy ions also found in this region. The authors examine H{sup +} and He{sup +} distribution functions from {approx} 1 to 160 eV using the Hot Plasma Composition Experiment instrument on AMPTE/CCE to investigate the thermal ion response to the waves. A total of 48 intervals were chosen on the basis of electromagnetic ion cyclotron (EMIC) wave activity: 24 with prevalent EMIC waves and 24 with no EMIC waves observed on the orbit. There is a close correlation between EMIC waves and perpendicularly heated ion distributions. For protons the perpendicular temperature increase is modest, about 5 eV, and is always observed at 90{degrees} pitch angles. This is consistent with a nonresonant interaction near the equator. By contrast, He{sup +} temperatures during EMIC wave events averaged 35 eV and sometimes exceeded 100 eV, indicating stronger interaction with the waves. Furthermore, heated He{sup +} ions have X-type distributions with maximum fluxes occurring at pitch angles intermediate between field-aligned and perpendicular directions. The X-type He{sup +} distributions are consistent with a gyroresonant interaction off the equator. The concentration of He{sup +} relative to H{sup +} is found to correlate with EMIC wave activity, but it is suggested that the preferential heating of He{sup +} accounts for the apparent increase in relative He{sup +} concentration by increasing the proportion of He{sup +} detected by the ion instrument. 35 refs., 8 figs., 1 tab.

  15. Wave modelling for the North Indian Ocean using MSMR analysed winds

    Digital Repository Service at National Institute of Oceanography (India)

    Vethamony, P.; Sudheesh, K.; Rupali, S.P.; Babu, M.T.; Jayakumar, S.; Saran, A.K.; Basu, S.K.; Kumar, R.; Sarkar, A.

    NCMRWF (National Centre for Medium Range Weather Forecast) winds assimilated with MSMR (Multi-channel Scanning Microwave Radiometer) winds are used as input to MIKE21 Offshore Spectral Wave model (OSW) which takes into account wind induced wave...

  16. Stochastic procedures for extreme wave induced responses in flexible ships

    Directory of Open Access Journals (Sweden)

    Jensen Jørgen Juncher

    2014-12-01

    Full Text Available Different procedures for estimation of the extreme global wave hydroelastic responses in ships are discussed. Firstly, stochastic procedures for application in detailed numerical studies (CFD are outlined. The use of the First Order Reliability Method (FORM to generate critical wave episodes of short duration, less than 1 minute, with prescribed probability content is discussed for use in extreme response predictions including hydroelastic behaviour and slamming load events. The possibility of combining FORM results with Monte Carlo simulations is discussed for faster but still very accurate estimation of extreme responses. Secondly, stochastic procedures using measured time series of responses as input are considered. The Peak-over-Threshold procedure and the Weibull fitting are applied and discussed for the extreme value predictions including possible corrections for clustering effects.

  17. Estimation of waves and ship responses using onboard measurements

    DEFF Research Database (Denmark)

    Montazeri, Najmeh

    This thesis focuses on estimation of waves and ship responses using ship-board measurements. This is useful for development of operational safety and performance efficiency in connection with the broader concept of onboard decision support systems. Estimation of sea state is studied using a set...

  18. Wave Dragon. Test to evaluate hydraulic response. Report phase A

    Energy Technology Data Exchange (ETDEWEB)

    Soerensen, H.C.; Friis-Madsen, E.

    1999-02-01

    Danish Maritime Institute has in the spring 1998 built a model in scale 1:50 of the wave energy converter Wave Dragon. The scale model is based on calculations performed by the inventor Erik Friis-Madsen from the consultant Loewenmark F.R.I. The scale model is tested in the wave tank at Aalborg University, the Hydraulic and Coastal Engineering Laboratory. This report deals with the results from this test (phase A of the test program). The objective of the test series was to get a judgement of the viability of Wave Dragon in extreme sea conditions in the Danish part of the North Sea at a water depth of 30 meters. The test series had to document: The viability of the Wave Dragon in extreme sea conditions up to 100-year waves; the hydraulic response in 7 different sea conditions where forces and movements have been registered. The main findings are: Wave Dragon has the expected behavior, i.e. the converter is able to survive a 100-year storm; An adjustment of the pitch of the converter could improve the energy efficiency; The forces in the mooring system and the junction between wave reflectors and the platform are acceptable. The forces and the movements are registered at 7 different sea conditions. Video recording has been taken during the test. Five of the sea conditions correspond to 'normal' waves in which power will be produced. Two sea conditions correspond to extreme wave situations. The duration of the registration in each sea conditions was approximately 1/2 an hour, i.e. 3.5 hours in scale 1:1. The conclusion is: The planned test series to evaluate the energy performance can start up (phase B of the test program); The energy efficiency is expected to be improved by a slight modification in the geometry of the Wave Dragon. The modifications can include the geometry of the front and the stabilising wing at the rear end of the platform. Further on changes are possible in the stiffness of the junction between the wave reflectors and the platform and

  19. Full-wave Analyses of Scattering of Electromagnetic Wave from the Weakly Ionized Plasma in Plane Geometry

    Institute of Scientific and Technical Information of China (English)

    Song Falun; Cao Jinxiang; Wang Ge

    2005-01-01

    The purpose of the present work is to present a full-wave analysis of scattering from the weakly ionized plasma in the plane geometry. We have yielded an approximate solution in an analytic form to the electromagnetic wave scattering from the weakly ionizsd plasma. In the normal and oblique incidence, the analytic solution works well, as compared with the exact solution and the solution based on the Wenzell-Kramers-Brillouin-Jeffreys (WKBJ) approximation to the uniform density profile.

  20. Forced Gravity Waves and the Tropospheric Response to Convection

    Science.gov (United States)

    Halliday, Oliver; Parker, Doug; Griffiths, Stephen; Stirling, Alison

    2017-04-01

    It has been known for some time that gravity waves facilitate atmospheric adjustment to convective heating. Further, convectively forced gravity waves condition the neighbouring atmosphere for the initiation and / or suppression of convection. Despite this, the radiation of gravity waves in macro-scale models (which are typically forced at the grid-scale, by existing parameterization schemes) is not well understood. We present here theoretical and numerical work directed toward improving our understanding of convectively forced gravity wave effects at the mesoscale. Using the linear hydrostatic equations of motion for an incompressible (but non-Boussinesq) fluid with vertically varying buoyancy frequency, we find a radiating solution to prescribed sensible heating. We then interrogate the spatial and temporal sensitivity of the vertical velocity and potential temperature response to different heating functions, considering the remote and near-field forced response both to steady and pulsed heating. We find that the meso-scale tropospheric response to convection is significantly dependent on the upward radiation characteristics of the gravity waves, which are in turn dependent upon the temporal and spatial structure of the source, and stratification of the domain. Moving from a trapped to upwardly-radiating solution there is a 50% reduction in tropospherically averaged vertical velocity, but significant perturbations persist for up to 4 hours in the far-field. Furthermore, we find the tropospheric adjustment to be sensitive to the horizontal length scale of the heating, observing a 20% reduction in vertical velocity when comparing the response from a 10 km to a 100 km heat source. We assess the implications for parameterization of convection in coarse-grained models in the light of these findings and argue that an idealized 'full-physics' nonlinear simulation of deep convection in the MetUM is qualitatively described by the linear solution: departures are quantified

  1. Most Likely Response Waves for Estimation of Extreme Value Ship Response Statistics

    DEFF Research Database (Denmark)

    Dietz, Jesper Skjoldager; Friis-Hansen, Peter; Jensen, Jørgen Juncher

    2004-01-01

    Fast and accurate methods for estimation of non-linear extreme value ship response statistics using 2D or 3D time-domain codes are of interest. The present study illustrates a new approach using Most Likely Response Waves (MLRW) to estimate the entire non-linear extreme response value distribution...

  2. Determination of the chiral coupling constants c(3) and c(4) in new pp and np partial-wave analyses

    NARCIS (Netherlands)

    Rentmeester, MCM; Timmermans, RGE; de Swart, JJ

    2003-01-01

    As a first result of two new partial-wave analyses, one of the pp and another one of the np scattering data below 500 MeV, we report a study of the long-range chiral two-pion exchange interaction which contains the chiral coupling constants c(1), c(3), and c(4). By using as input a theoretical value

  3. Analysing responses to climate change through the lens of reflexivity.

    Science.gov (United States)

    Davidson, Debra

    2012-12-01

    Sociologists are increasingly directing attention toward social responses to climate change. As is true of any new field of inquiry, theoretical frameworks guiding the research to date have room for improvement. One advance could be achieved through closer engagement with Reflexivity Theory, particularly the work of Margaret Archer, who asks just how individuals come to give attention to certain problems, and formulate responses to them. Individuals vary significantly in regard to their understanding of and concern for anthropogenic climate change, and these standpoints in turn influence commitment to mitigation and adaptation. The emergent social interactions among all such agents in turn influence the morphogenetic trajectories through which social structures will evolve, but the role of 'meta-reflexives' is particularly crucial. Identifying pathways of individual climate change reflexivity can make a valuable contribution to our understanding of the potential for and nature of collective responses. In this paper, I explore climate change reflexivity, with particular attention to climate change meta-reflexives, through a qualitative analysis of personal interviews with residents of two small communities in Alberta, Canada. Applying Reflexivity Theory to this context articulates dimensions of reflexive processing not elaborated in current theoretical treatments, including future outlook and comfort with uncertainty, among others.

  4. The response of superpressure balloons to gravity wave motions

    Science.gov (United States)

    Vincent, R. A.; Hertzog, A.

    2014-04-01

    Superpressure balloons (SPB), which float on constant density (isopycnic) surfaces, provide a unique way of measuring the properties of atmospheric gravity waves (GW) as a function of wave intrinsic frequency. Here we devise a quasi-analytic method of investigating the SPB response to GW motions. It is shown that the results agree well with more rigorous numerical simulations of balloon motions and provide a better understanding of the response of SPB to GW, especially at high frequencies. The methodology is applied to ascertain the accuracy of GW studies using 12 m diameter SPB deployed in the 2010 Concordiasi campaign in the Antarctic. In comparison with the situation in earlier campaigns, the vertical displacements of the SPB were measured directly using GPS. It is shown using a large number of Monte Carlo-type simulations with realistic instrumental noise that important wave parameters, such as momentum flux, phase speed and wavelengths, can be retrieved with good accuracy from SPB observations for intrinsic wave periods greater than ca. 10 min. The noise floor for momentum flux is estimated to be ca. 10-4 mPa.

  5. Linear density response function in the projector augmented wave method

    DEFF Research Database (Denmark)

    Yan, Jun; Mortensen, Jens Jørgen; Jacobsen, Karsten Wedel;

    2011-01-01

    We present an implementation of the linear density response function within the projector-augmented wave method with applications to the linear optical and dielectric properties of both solids, surfaces, and interfaces. The response function is represented in plane waves while the single......-particle eigenstates can be expanded on a real space grid or in atomic-orbital basis for increased efficiency. The exchange-correlation kernel is treated at the level of the adiabatic local density approximation (ALDA) and crystal local field effects are included. The calculated static and dynamical dielectric...... functions of Si, C, SiC, AlP, and GaAs compare well with previous calculations. While optical properties of semiconductors, in particular excitonic effects, are generally not well described by ALDA, we obtain excellent agreement with experiments for the surface loss function of graphene and the Mg(0001...

  6. Local helioseismic and spectroscopic analyses of interactions between acoustic waves and a sunspot

    CERN Document Server

    Rajaguru, S P; Sankarasubramanian, K; Couvidat, S; 10.1088/2041-8205/721/2/L86

    2010-01-01

    Using a high cadence imaging spectropolarimetric observation of a sunspot and its surroundings in magnetically sensitive (FeI 6173 A) and insensitive (FeI 7090 A) upper photospheric absorption lines, we map the instantaneous wave phases and helioseismic travel times as a function of observation height and inclination of magnetic field to the vertical. We confirm the magnetic inclination angle dependent transmission of incident acoustic waves into upward propagating waves, and derive (1) proof that helioseismic travel times receive direction dependent contributions from such waves and hence cause errors in conventional flow inferences, (2) evidences for acoustic wave sources beneath the umbral photosphere, and (3) significant differences in travel times measured from the chosen magnetically sensitive and insensitive spectral lines.

  7. Physics of the Geospace Response to Powerful HF Radio Waves

    Science.gov (United States)

    2012-10-31

    studies of the response of the Earth’s space plasma to high-power HF radio waves from the High-frequency Active Auroral Research Program ( HAARP ...of HF heating and explored to simulate artificial ducts. DMSP- HAARP experiments revealed that HF-created ion outflows and artificial density ducts...in the topside ionosphere appeared faster than predicted by the models, pointing to kinetic (suprathermal) effects. CHAMP/GRACE- HAARP experiments

  8. Numerical Simulation of Seabed Response and Liquefaction due to Non-linear Waves

    Institute of Scientific and Technical Information of China (English)

    ZHANG Jin-feng; ZHANG Qing-he; HAN Tao; QIN Chong-ren

    2005-01-01

    Based on Biot's consolidation theory, a two-dimensional model for computation of the seabed response to waves is presented with the finite element method. Numerical results for different wave conditions are obtained, and the effects of wave non-linearity on the wave-induced seabed response are examined. Moreover, the wave-induced momentary liquefaction in uniform and inhomogeneous seabeds is investigated. It is shown that the wave non-linearity affects the distribution of the wave-induced pore pressure and effective stresses, while the influence of wave non-linearity on the seabed liquefaction potential is not so significant.

  9. Optimal mother wavelet-based Lamb wave analyses and damage detection for composite structures

    Institute of Scientific and Technical Information of China (English)

    Li Fucai; Meng Guang; Ye Lin

    2007-01-01

    With the purpose of on-line structural health monitoring, a transducer network was embedded into composite structure to minimize the influence of surroundings. The intrinsic dispersion characteristic of Lamb wave makes the wavelet transform an effective signal processing method for guided waves. To get high precision in feature extraction, an information entropy-based optimal mother wavelet selection approach was proposed, which was used to choose the most appropriate basis function for particular Lamb wave analysis. By using the embedded sensor network and extracting time-of-flight, delamination in the composite laminate was identified and located. The results demonstrate the effectiveness of the proposed methods.

  10. Hydraulic Response of the Wave Energy Converter Wave Dragon in Nissum Bredning

    DEFF Research Database (Denmark)

    Kofoed, Jens Peter; Frigaard, Peter

    This report deals with the hydraulic performance of the wave energy converter Wave Dragon, Nissum Bredning prototype.......This report deals with the hydraulic performance of the wave energy converter Wave Dragon, Nissum Bredning prototype....

  11. Wave-current interactions in deep water conditions: field measurements and analyses

    Science.gov (United States)

    Rougier, Gilles; Rey, Vincent; Molcard, Anne

    2015-04-01

    The study of wave - current interaction has drawn interest in oceanography, ocean engineering, maritime navigation and for tides or waves power device design. In the context of the hydrodynamics study along the French Mediterranean coast, a current profiler was deployed near Toulon at the south of the "Port Cros" island. This coastal zone is characterized by a steep slope, the water depth varying from tens meters to several thousand meters over few kilometers from the coast. An ambient current, the "Northern Current", coming from the Ligurian sea (area of Genoa, Italy) and following the coast up to Toulon, is present all over the year. Its mean surface velocity is of about 0.30 m/s, its flow rate of about 1.5 Sv. The region is exposed to two dominating winds: the Mistral, coming from North-West, and Eastern winds. Both generate swell and/or wind waves in either following or opposing current conditions with respect to the Northern Current. A current profiler equipped with a wave tracking system (ACPD workhorse from RDI) was deployed from July to October 2014 in deep water conditions (depth of about 500m). The mooring system allowed the ADCP to measure the current profile from the sea surface down to 25m depth, which corresponds more or less to the depth of influence of waves of periods up to 10s. The collected data include energetic wave conditions in either following or opposing current conditions. The current intensity and its vertical profiles have shown a significant temporal variability according to the meteorological conditions. Effects of the wave conditions on the current properties are discussed. ACKNOWLEDGEMENTS This work was supported by the program BOMBYX and the ANR grant No ANR-13-ASTR-0007.

  12. A Study for Visual Realism of Designed Pictures on Computer Screens by Investigation and Brain-Wave Analyses.

    Science.gov (United States)

    Wang, Lan-Ting; Lee, Kun-Chou

    2016-08-01

    In this article, the visual realism of designed pictures on computer screens is studied by investigation and brain-wave analyses. The practical electroencephalogram (EEG) measurement is always time-varying and fluctuating so that conventional statistical techniques are not adequate for analyses. This study proposes a new scheme based on "fingerprinting" to analyze the EEG. Fingerprinting is a technique of probabilistic pattern recognition used in electrical engineering, very like the identification of human fingerprinting in a criminal investigation. The goal of this study was to assess whether subjective preference for pictures could be manifested physiologically by EEG fingerprinting analyses. The most important advantage of the fingerprinting technique is that it does not require accurate measurement. Instead, it uses probabilistic classification. Participants' preference for pictures can be assessed using fingerprinting analyses of physiological EEG measurements.

  13. Autism spectrum disorders and the amplitude of auditory brainstem response wave I.

    Science.gov (United States)

    Santos, Mariline; Marques, Cristina; Nóbrega Pinto, Ana; Fernandes, Raquel; Coutinho, Miguel Bebiano; Almeida E Sousa, Cecília

    2017-04-01

    To determine whether children with autism spectrum disorders (ASDs) have an increased number of wave I abnormal amplitudes in auditory brainstem responses (ABRs) than age- and sex-matched typically developing children. This analytical case-control study compared patients with ASDs between the ages of 2 and 6 years and children who had a language delay not associated with any other pathology. Amplitudes of ABR waves I and V; absolute latencies (ALs) of waves I, III, and V; and interpeak latencies (IPLs) I-III, III-IV, and I-V at 90 dB were compared between ASD patients and normally developing children. The study enrolled 40 children with documented ASDs and 40 age- and sex-matched control subjects. Analyses of the ABR showed that children with ASDs exhibited higher amplitudes of wave 1 than wave V (35%) more frequently than the control group (10%), and this difference between groups reached statistical significance by Chi-squared analysis. There were no significant differences in ALs and IPLs between ASD children and matched controls. To the best of our knowledge, this is the first case-control study testing the amplitudes of ABR wave I in ASD children. The reported results suggest a potential for the use of ABR recordings in children, not only for the clinical assessment of hearing status, but also for the possibility of using amplitude of ABR wave I as an early marker of ASDs allowing earlier diagnosis and intervention. Autism Res 2017. © 2017 International Society for Autism Research, Wiley Periodicals, Inc.

  14. Caisson Movement Caused by Wave Slamming—a Comparison of ABAQUS and FLAC Analyses

    DEFF Research Database (Denmark)

    Andersen, Lars; Burcharth, Hans F.; Andersen, Thomas Lykke;

    2010-01-01

    During wave slamming, caisson movement may occur as a combination of sliding along the caisson–foundation interface and local failure in the foundation and seabed. The paper presents a comparison between different techniques applied to the analysis of this movement. Thus, a finite-difference anal......During wave slamming, caisson movement may occur as a combination of sliding along the caisson–foundation interface and local failure in the foundation and seabed. The paper presents a comparison between different techniques applied to the analysis of this movement. Thus, a finite...

  15. Subshell fitting of relativistic atomic core electron densities for use in QTAIM analyses of ECP-based wave functions.

    Science.gov (United States)

    Keith, Todd A; Frisch, Michael J

    2011-11-17

    Scalar-relativistic, all-electron density functional theory (DFT) calculations were done for free, neutral atoms of all elements of the periodic table using the universal Gaussian basis set. Each core, closed-subshell contribution to a total atomic electron density distribution was separately fitted to a spherical electron density function: a linear combination of s-type Gaussian functions. The resulting core subshell electron densities are useful for systematically and compactly approximating total core electron densities of atoms in molecules, for any atomic core defined in terms of closed subshells. When used to augment the electron density from a wave function based on a calculation using effective core potentials (ECPs) in the Hamiltonian, the atomic core electron densities are sufficient to restore the otherwise-absent electron density maxima at the nuclear positions and eliminate spurious critical points in the neighborhood of the atom, thus enabling quantum theory of atoms in molecules (QTAIM) analyses to be done in the neighborhoods of atoms for which ECPs were used. Comparison of results from QTAIM analyses with all-electron, relativistic and nonrelativistic molecular wave functions validates the use of the atomic core electron densities for augmenting electron densities from ECP-based wave functions. For an atom in a molecule for which a small-core or medium-core ECPs is used, simply representing the core using a simplistic, tightly localized electron density function is actually sufficient to obtain a correct electron density topology and perform QTAIM analyses to obtain at least semiquantitatively meaningful results, but this is often not true when a large-core ECP is used. Comparison of QTAIM results from augmenting ECP-based molecular wave functions with the realistic atomic core electron densities presented here versus augmenting with the limiting case of tight core densities may be useful for diagnosing the reliability of large-core ECP models in

  16. Rapid Response Measurements of Hurricane Waves and Storm Surge

    Science.gov (United States)

    Gravois, U.

    2010-12-01

    Andrew (1992), Katrina (2005), and Ike (2008) are recent examples of extensive damage that resulted from direct hurricane landfall. Some of the worst damages from these hurricanes are caused by wind driven waves and storm surge flooding. The potential for more hurricane disasters like these continues to increase as a result of population growth and real estate development in low elevation coastal regions. Observational measurements of hurricane waves and storm surge play an important role in future mitigation efforts, yet permanent wave buoy moorings and tide stations are more sparse than desired. This research has developed a rapid response method using helicopters to install temporary wave and surge gauges ahead of hurricane landfall. These temporary installations, with target depths from 10-15 m and 1-7 km offshore depending on the local shelf slope, increase the density of measurement points where the worst conditions are expected. The method has progressed to an operational state and has successfully responded to storms Ernesto (2006), Noel (2007), Fay (2008), Gustav (2008), Hanna (2008) and Ike (2008). The temporary gauges are pressure data loggers that measure at 1 Hz continuously for 12 days and are post-processed to extract surge and wave information. For the six storms studied, 45 out of 49 sensors were recovered by boat led scuba diver search teams, with 43 providing useful data for an 88 percent success rate. As part of the 20 sensor Hurricane Gustav response, sensors were also deployed in lakes and bays inLouisiana, east of the Mississippi river delta. Gustav was the largest deployment to date. Generally efforts were scaled back for storms that were not anticipated to be highly destructive. For example, the cumulative total of sensors deployed for Ernesto, Noel, Fay and Hanna was only 20. Measurement locations for Gustav spanned over 800 km of exposed coastline from Louisiana to Florida with sensors in close proximity to landfall near Cocodrie

  17. Full-Wave Analyses of Nano-Electromechanical Systems Integrated Multifunctional Reconfigurable Antennas

    OpenAIRE

    Yuan, Xiaoyan

    2009-01-01

    This thesis work builds upon the theoretical studies and full-wave analysis of radio frequency micro- and nano-electromechanical systems (RF M/NEMS) integrated multi-functional reconfigurable antennas(MRAs). This is a part of the overall M/NEMS research efforts performed in the RF NEMS Laboratory at USU, which includes design, microfabrication, test, and characterization of M/NEMS integrated congitive wireless communication systems (fig. A.1). The thesis work focuses on two MRAs. 1) A tri...

  18. Physical Modelling of an Array of 25 Heaving Wave Energy Converters to Quantify Variation of Response and Wave Conditions

    DEFF Research Database (Denmark)

    2013-01-01

    for the evaluation of array interaction models and environmental scale models. Each wave energy converter unit has a diameter of 0.315 m and power absorption is due to friction of both a power take off system and bearings. Response is measured on all floats and surge force on five floats. Wave gauges are located...

  19. Analyses of the temperature field of traveling-wave rotary ultrasonic motors.

    Science.gov (United States)

    Lu, Xiaolong; Hu, Junhui; Zhao, Chunsheng

    2011-12-01

    In this paper, the transient and steady-state temperature field of a traveling-wave rotary ultrasonic motor is analyzed by the finite element method, based on a theoretical model of power loss of this motor in rated operation. Using this model, the temperature field of this motor is calculated and the effects of the heat conductivity of friction material, motor size, ambient temperature, and pressure on the temperature field are estimated. The calculated temperature distribution and transient temperature change agree with the experimental results. The variation of heat conductivity of the friction material has little effect on the minimum temperature in the motor but this variation seriously affects the maximum temperature in the motor when the heat conductivity of the friction material is lower than 0.5 W/(m°C). Two indices are defined to express the non-uniformity of temperature field and how quickly the temperature field reaches its steady state for traveling-wave ultrasonic motors of different sizes. It is found that traveling-wave ultrasonic motors with different sizes have different nonuniformity of temperature field and take different amounts of time to reach thermal steady state. The maximum temperature rise is lower when the ambient temperature is higher; the maximum temperature increases as the vacuum degree increases and it is not affected by the vacuum degree when the vacuum degree is too high (<10(-3) Pa).

  20. Shock Wave Speed and Transient Response of PE Pipe with Steel-Mesh Reinforcement

    OpenAIRE

    2016-01-01

    A steel mesh can improve the tensile strength and stability of a polyethylene (PE) pipe in a water supply pipeline system. However, it can also cause more severe water hammer hazard due to increasing wave speed. In order to analyze the influence of the steel mesh on the shock wave speed and transient response processes, an improved wave speed formula is proposed by incorporating the equivalent elastic modulus. A field measurement validates the wave speed formula. Moreover, the transient wave ...

  1. Estimations of On-site Directional Wave Spectra from Measured Ship Responses

    DEFF Research Database (Denmark)

    Nielsen, Ulrik Dam

    2006-01-01

    include an quivalence of energy in the governing equations and, as regards the parametric concept, a frequency dependent spreading of the waves is introduced. The paper includes an extensive analysis of full-scale measurements for which the directional wave spectra are estimated by the two ship response......In general, two main concepts can be applied to estimate the on-site directional wave spectrum on the basis of ship response measurements: 1) a parametric method which assumes the wave spectrum to be composed by parameterised wave spectra, or 2) a non-parametric method where the directional wave...

  2. Estimations of On-site Directional Wave Spectra from Measured Ship Responses

    DEFF Research Database (Denmark)

    Nielsen, Ulrik Dam

    2006-01-01

    include an quivalence of energy in the governing equations and, as regards the parametric concept, a frequency dependent spreading of the waves is introduced. The paper includes an extensive analysis of full-scale measurements for which the directional wave spectra are estimated by the two ship response......In general, two main concepts can be applied to estimate the on-site directional wave spectrum on the basis of ship response measurements: 1) a parametric method which assumes the wave spectrum to be composed by parameterised wave spectra, or 2) a non-parametric method where the directional wave...

  3. URANS simulations of ship motion responses in long-crest irregular waves

    Institute of Scientific and Technical Information of China (English)

    沈志荣; 叶海轩; 万德成

    2014-01-01

    In this paper, numerical prediction of ship motion responses in long-crest irregular waves by the URANS-VOF method is presented. A white noise spectrum is applied to generate the incoming waves to evaluate the motion responses. The procedure can replace a decade of simulations in regular wave with one single run to obtain a complete curve of linear motion response, conside-rably reducing computation time. A correction procedure is employed to adjust the wave generation signal based on the wave spe-ctrum and achieves fairly better results in the wave tank. Three ship models with five wave conditions are introduced to validate the method. The computations in this paper are completed by using the solver naoe-FOAM-SJTU, a solver developed for ship and ocean engineering based on the open source code OpenFOAM. The computational motion responses by the irregular wave procedure are compared with the results by regular wave, experiments and strip theory. Transfer functions by irregular wave closely agree with the data obtained in the regular waves, showing negligible difference. The comparison between computational results and experiments also show good agreements. The results better predicted by CFD method than strip theories indicate that this method can compensate for the inaccuracy of the strip theories. The results confirm that the irregular wave procedure is a promising method for the accurate prediction of motion responses with less accuracy loss and higher efficiency compared with the regular wave procedure.

  4. Covariant tensor formalism for partial wave analyses of $\\psi$ decays into $\\gamma\\gamma V$

    OpenAIRE

    Dulat, Sayipjamal; Zou, Bing-Song; Wu, Ji-Min

    2004-01-01

    The double radiative decays $\\psi\\to\\gamma\\gamma V$ with $V\\equiv \\rho,\\omega,\\phi$ have a potential to provide information on the flavor content of any meson resonances (R) with positive charge parity ($C=+$) and mass above 1 GeV through $\\psi\\to\\gamma R \\to\\gamma\\gamma V$. To get the information, one needs both high statistic data and partial wave analysis (PWA). While high statistic data will be available soon at CLEO-c and BES-III, here we provide theoretical PWA formulae for these $\\psi$...

  5. Analyses of electrostatic solitary waves (ESWs) observed by Kaguya near the Moon

    Science.gov (United States)

    Hashimoto, K.; Hashitani, M.; Omura, Y.; Kasahara, Y.; Kojima, H.; Ono, T.; Tsunakawa, H.

    2011-12-01

    In KAGUYA (SELENE) LRS [1], WFC-L [2] observes waveforms of plasma waves in 100Hz-100kHz and a lot of electrostatic solitary waves (ESWs) have been observed. Some results were reported [3]. Although the orthogonal dipole antennas are generally used in the observations, sometimes a pair of monopole antennas were used. We analyze observations mainly by the latter antennas in the present study. Observed waveforms are fitted to ideal ESW waveforms. The waveforms observed by the monopole mode are susceptive to noises and generally they are not similar each other. Since the waveforms observed by the dipole mode are less affected by noises, we re-analyzed the data by fitting these waveforms to the ideal ESW waveforms. The observed ESWs have often components perpendicular to the background magnetic field. This means that the ESW potential structure has two dimensions and they are observed near the generation regions. The propagation velocity, the potential width, the potential depth, etc. of each ESW are also evaluated by comparing the waveforms observed by the monopole antennas. The data fitted to the dipole waveforms are used as references. Acknowledgments: The SELENE project has been organized by the Japan Aerospace Exploration Agency (JAXA). The authors express their thanks to all members of the SELENE project team. References [1] Takayuki Ono, Atsushi Kumamoto, Yasushi Yamaguchi, Atsushi Yamaji, Takao Kobayashi, Yoshiya Kasahara, and Hiroshi Oya, Instrumentation and observation target of the Lunar Radar Sounder (LRS) experiment on-board the SELENE spacecraft, Earth Planets Space, 60, 321-332, 2008. [2] Y. Kasahara, Y. Goto, K. Hashimoto, T. Imachi, A. Kumamoto, T. Ono, and H. Matsumoto, Plasma Wave Observation Using Waveform Capture in the Lunar Radar Sounder on board the SELENE Spacecraft, Earth, Planets and Space, 60, 341-351, 2008. [3] K. Hashimoto, M. Hashitani, Y. Kasahara, Y. Omura, M.N. Nishino, Y. Saito, S. Yokota, T. Ono, H. Tsunakawa, H. Shibuya, M

  6. Forest response to heat waves at the dry timberline

    Science.gov (United States)

    Yakir, D.; Rotenberg, E.; Tatrinov, F.; Ogee, J.; Maseyk, K.

    2012-04-01

    Predictions of climate change consistently indicate continuous warming and drying for the entire Mediterranean basin and other regions during the next century. Investigating forest functioning at the current dry and hot "timberline" has therefore implications for predicting future forest distribution. In such investigations we should consider the forest adjustments to extreme conditions both at the long-term average climate basis, as at the time-scale of episodic extreme events, such as heat waves and droughts. Investigating both aspects in a 45-yr old semi-arid pine forest at the dry timberline (MuSICA) was used to test our understandings of underlying processes, and our ability to account for such differential responses.

  7. Analyses of axisymmetric waves in layered piezoelectric rods and their composites.

    Science.gov (United States)

    Nayfeh, A H; Abdelrahman, W G; Nagy, P B

    2000-10-01

    An exact treatment of the propagation of axisymmetric waves in coaxial anisotropic assembly of piezoelectric rod systems is presented. The rod system consists of an arbitrary number of coaxial layers, each possessing transversely isotropic symmetry properties. The treatment, which is based on the transfer matrix technique, is capable of deriving the dispersion relations for a variety of situations. These include the case of a single rod system that is either embedded in an infinitely extended solid or fluid host or kept free. The procedure is also adapted to derive approximate solutions for the cases of a periodic fiber distribution in a matrix material, which model unidirectional fiber-reinforced composites. The results are numerically illustrated for a widely used piezoelectric-polymer composite. It is seen that piezoelectric coupling can significantly change the morphology of the dispersive behavior of the composite.

  8. A robust approach for analysing dispersion of elastic waves in an orthotropic cylindrical shell

    Science.gov (United States)

    Kaplunov, J.; Nobili, A.

    2017-08-01

    Dispersion of elastic waves in a thin orthotropic cylindrical shell is considered, within the framework of classical 2D Kirchhoff-Love theory. In contrast to direct multi-parametric analysis of the lowest propagating modes, an alternative robust approach is proposed that simply requires evaluation of the evanescent modes (quasi-static edge effect), which, at leading order, do not depend on vibration frequency. A shortened dispersion relation for the propagating modes is then derived by polynomial division and its accuracy is numerically tested against the full Kirchhoff-Love dispersion relation. It is shown that the same shortened relation may be also obtained from a refined dynamic version of the semi-membrane theory for cylindrical shells. The presented results may be relevant for modelling various types of nanotubes which, according to the latest experimental findings, possess strong material anisotropy.

  9. Interferometer responses to gravitational waves: Comparing FINESSE simulations and analytical solutions

    CERN Document Server

    Bond, Charlotte; Freise, Andreas

    2013-01-01

    A comparison of analytic calculations and FINESSE simulations of interferometer responses to gravitational wave strain. The response to a gravitational wave is gradually built up from the effect of modulating a space by a gravitational wave to Sagnac and Michelson interferometers with and without arm cavities. This document details the steps necessary to perform such simulations in FINESSE and explicitly derives the interferometer response equations.

  10. The Core Mouse Response to Infection by Neospora Caninum Defined by Gene Set Enrichment Analyses

    Science.gov (United States)

    Ellis, John; Goodswen, Stephen; Kennedy, Paul J; Bush, Stephen

    2012-01-01

    In this study, the BALB/c and Qs mouse responses to infection by the parasite Neospora caninum were investigated in order to identify host response mechanisms. Investigation was done using gene set (enrichment) analyses of microarray data. GSEA, MANOVA, Romer, subGSE and SAM-GS were used to study the contrasts Neospora strain type, Mouse type (BALB/c and Qs) and time post infection (6 hours post infection and 10 days post infection). The analyses show that the major signal in the core mouse response to infection is from time post infection and can be defined by gene ontology terms Protein Kinase Activity, Cell Proliferation and Transcription Initiation. Several terms linked to signaling, morphogenesis, response and fat metabolism were also identified. At 10 days post infection, genes associated with fatty acid metabolism were identified as up regulated in expression. The value of gene set (enrichment) analyses in the analysis of microarray data is discussed. PMID:23012496

  11. Structural analyses of very large semi-submersibles in waves; Choogata hansensuishiki futai no harochu kozo oto kaiseki

    Energy Technology Data Exchange (ETDEWEB)

    Iijima, K.; Yoshida, K.; Suzuki, H. [The University of Tokyo, Tokyo (Japan)

    1997-08-01

    An analysis method in which the technique of a vehicle obtained when a three-dimensional singular point distribution method and Kagemoto`s mutual interaction theory are combined was expanded for the fluid area was proposed as the structural analysis of very large semi-submersibles in waves. A partial structure method is used for the structure. In a fluid area, the number of unknown quantities appearing in a final expression could be largely reduced by introducing the new concept of a group body. In this process, both hydro-elasticity and hydrodynamic mutual interaction are considered. As a result, floating bodies that could not be previously calculated can be modeled as a three-dimensional frame structure and the response analysis in waves can be carried out without damaging the accuracy. The calculation result is used as the input data required for analyzing the structural fatigue locally during structural design of very large semi-submersibles in the 3,000 (m) class. This study can present a series of procedures between the response analysis of very large floating bodies in waves and the structural design. 11 refs., 14 figs., 1 tab.

  12. Dynamic Response of Coarse Granular Material to Wave Load

    DEFF Research Database (Denmark)

    Ibsen, Lars Bo

    1998-01-01

    The soil beneath vertical breakwaters is subjected to a combination of forces induced by the waves. The forces acting on the soil can be characterized as 1) static load due to submerged weight of the structure, 2) quasi-static forces induced by cyclic wave loading, and 3) wave impact from breakin...

  13. Display depth analyses with the wave aberration for the auto-stereoscopic 3D display

    Science.gov (United States)

    Gao, Xin; Sang, Xinzhu; Yu, Xunbo; Chen, Duo; Chen, Zhidong; Zhang, Wanlu; Yan, Binbin; Yuan, Jinhui; Wang, Kuiru; Yu, Chongxiu; Dou, Wenhua; Xiao, Liquan

    2016-07-01

    Because the aberration severely affects the display performances of the auto-stereoscopic 3D display, the diffraction theory is used to analyze the diffraction field distribution and the display depth through aberration analysis. Based on the proposed method, the display depth of central and marginal reconstructed images is discussed. The experimental results agree with the theoretical analyses. Increasing the viewing distance or decreasing the lens aperture can improve the display depth. Different viewing distances and the LCD with two lens-arrays are used to verify the conclusion.

  14. An Experimental Investigation of the Responses of Classic Spar Platform Subjected to Bi-directional Waves

    Directory of Open Access Journals (Sweden)

    V.J. Kurian

    2015-01-01

    Full Text Available The effect of the bi-directional short-crested waves on the dynamic motion responses of the moored classic spar is demonstrated from the results of the models test in this study. Practically in the design of offshore structures, long-crested or 2-dimensional wave properties that propagated to one direction are considered. Even though such long-crested wave is widely used for the design purposes, it is hardly determined in the real sea. The wind generated sea state in the real sea conditions are indeed well represented by the short-crested waves. Short-crested waves are defined as linear summation of long-crested wave series that propagated to different directions. Hence, the motions of the model were investigated experimentally by conducting the wave tank tests in the wave tank of Offshore Laboratory of Universiti Teknologi PETRONAS. Five groups of bi-directional wave series were defined and exerted on the classic spar model, which fabricated by using steel with scaling factor of 1:100. From the results measured, it was found that similar trends of the responses in term of Response Amplitude Operator (RAO for surge, heave and pitch motions were obtained. Maximum responses of surge, heave and pitch were found due to wave crossing angle 90°, while minimum response was found due to wave crossing angle 135°, respectively. It could be concluded that the wave crossing angle 90° (BD3 gives the widest spreading for short crested waves, while the wave crossing angle 135° (BD4 gives the narrowest spreading for short crested waves.

  15. Coronal Response to an EUV Wave from DEM Analysis

    Science.gov (United States)

    Vanninathan, K.; Veronig, A. M.; Dissauer, K.; Madjarska, M. S.; Hannah, I. G.; Kontar, E. P.

    2015-10-01

    Extreme-Ultraviolet (EUV) waves are globally propagating disturbances that have been observed since the era of the Solar and Heliospheric Observatory/Exteme-ultraviolet Imaging Telescope instrument. Although the kinematics of the wave front and secondary wave components have been widely studied, there is not much known about the generation and plasma properties of the wave. In this paper we discuss the effect of an EUV wave on the local plasma as it passes through the corona. We studied the EUV wave, generated during the 2011 February 15 X-class flare/coronal mass ejection event, using Differential Emission Measure diagnostics. We analyzed regions on the path of the EUV wave and investigated the local density and temperature changes. From our study we have quantitatively confirmed previous results that during wave passage the plasma visible in the Atmospheric Imaging Assembly (AIA) 171 Å channel is getting heated to higher temperatures corresponding to AIA 193 and 211 Å channels. We have calculated an increase of 6%-9% in density and 5%-6% in temperature during the passage of the EUV wave. We have compared the variation in temperature with the adiabatic relationship and have quantitatively demonstrated the phenomenon of heating due to adiabatic compression at the wave front. However, the cooling phase does not follow adiabatic relaxation but shows slow decay indicating slow energy release being triggered by the wave passage. We have also identified that heating is taking place at the front of the wave pulse rather than at the rear. Our results provide support for the case that the event under study here is a compressive fast-mode wave or a shock.

  16. Whales and waves: Humpback whale foraging response and the shoaling of internal waves at Stellwagen Bank

    Science.gov (United States)

    Pineda, Jesús; Starczak, Victoria; Silva, José C. B.; Helfrich, Karl; Thompson, Michael; Wiley, David

    2015-04-01

    We tested the hypothesis that humpback whales aggregate at the southern flank of Stellwagen Bank (SB) in response to internal waves (IWs) generated semidiurnally at Race Point (RP) channel because of the presence of their preferred prey, planktivorous fish, which in turn respond to zooplankton concentrated by the predictable IWs. Analysis of synthetic aperture radar (SAR) images indicates that RP IWs approach the southern flank of SB frequently (˜62% of the images). Published reports of whale sighting data and archived SAR images point to a coarse spatial coincidence between whales and Race Point IWs at SB's southern flank. The responses of whales to IWs were evaluated via sightings and behavior of humpback whales, and IWs were observed in situ by acoustic backscatter and temperature measurements. Modeling of IWs complemented the observations, and results indicate a change of ˜0.4 m/s in current velocity, and ˜1.5 Pa in dynamic pressure near the bottom, which may be sufficient for bottom fish to detect the IWs. However, fish were rare in our acoustic observations, and fish response to the IWs could not be evaluated. RP IWs do not represent the leading edge of the internal tide, and they may have less mass-transport potential than typical coastal IWs. There was large interannual variability in whale sightings at SB's southern flank, with decreases in both numbers of sightings and proportion of sightings where feeding was observed from 2008 to 2013. Coincidence of whales and IWs was inconsistent, and results do not support the hypothesis.

  17. Analysis of the frequency-dependent response to wave forcing in the extratropics

    Directory of Open Access Journals (Sweden)

    A. J. Haklander

    2006-01-01

    Full Text Available A quasigeostrophic model for the frequency-dependent response of the zonal-mean flow to planetary-wave forcing at Northern Hemisphere (NH midlatitudes is applied to 4-D-Var ECMWF analysis data for six extended winter seasons. The theoretical response is a non-linear function of the frequency of the forcing, the thermal damping time α−1, and a scaling parameter µ which includes the aspect ratio of the meridional to the vertical length scale of the response. Regression of the calculated response from the analyses onto the theoretical response yields height-dependent estimates for both α−1 and µ. The thermal damping time estimated from this dynamical model is about 2 days in the troposphere, 7–10 days in the stratosphere, and 2–4 days in the lower mesosphere. For the stratosphere and lower mesosphere, the estimates lie within the range of existing radiative damping time estimates, but for the troposphere they are significantly smaller.

  18. Hydrodynamic responses of a thin floating disk to regular waves

    CERN Document Server

    Yiew, Lucas; Meylan, Michael; French, Ben; Thomas, Giles

    2015-01-01

    Laboratory wave basin measurements of the surge, heave and pitch of a floating plastic disk caused by regular incident waves are presented. The measurements are used to validate two theoretical models: one based on slope-sliding theory and the other on combined potential-flow and thin-plate theories.

  19. Rapid Response: D-Wave Effort Debrief Welcome, Logistics

    Energy Technology Data Exchange (ETDEWEB)

    Eidenbenz, Stephan Johannes [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2016-10-11

    The main objects of this project is to develop a diverse and sizable workforce, community, interest within LANL for D-Wave and Quantum Computing; identify promising application areas/problems for future projects; and complement other D-Wave work at LANL (LDRD DR, ASC).

  20. Coronal response to an EUV wave from DEM analysis

    CERN Document Server

    Vanninathan, K; Dissauer, K; Madjarska, M S; Hannah, I G; Kontar, E P

    2015-01-01

    EUV (Extreme-Ultraviolet) waves are globally propagating disturbances that have been observed since the era of the SoHO/EIT instrument. Although the kinematics of the wave front and secondary wave components have been widely studied, there is not much known about the generation and plasma properties of the wave. In this paper we discuss the effect of an EUV wave on the local plasma as it passes through the corona. We studied the EUV wave, generated during the 2011 February 15 X-class flare/CME event, using Differential Emission Measure diagnostics. We analyzed regions on the path of the EUV wave and investigated the local density and temperature changes. From our study we have quantitatively confirmed previous results that during wave passage the plasma visible in the Atmospheric Imaging Assembly (AIA) 171A channel is getting heated to higher temperatures corresponding to AIA 193A and 211A channels. We have calculated an increase of 6 - 9% in density and 5 - 6% in temperature during the passage of the EUV wav...

  1. ASPECTS REGARDING INTERNATIONAL RESPONSIBILITY BY ANALYSING THE AGENCY RELATIONSHIP BETWEEN THE INTERNATIONAL ORGANIZATION AND THE STATE

    Directory of Open Access Journals (Sweden)

    Ovidiu-Emilian IVĂNESCU

    2016-05-01

    Full Text Available The study analyses the consequences for the responsibility of the organization and the relevant state of an agency relationship between an international organization acting as a principal and a state acting as its agent. It is prouved that an international organization may be responsible for damage caused by the conduct of the state. We can also sustain that the state itself may bear responsability for having established or for not having terminated the agency relationship if it commits wrongful conduct on behalf of the international organization.

  2. Dynamic Response of Stiffened Plates with Holes Subjected to Shock Waves and Fragments

    Institute of Scientific and Technical Information of China (English)

    刘彦; 张庆明; 黄风雷

    2004-01-01

    The power field of shock waves and fragments is analyzed and set up, and the damage modes of stiffened plates are put forward. According to the structural characters of the stiffened plates investigated and the properties of the shock waves and fragments, the experiments on the shock waves acting on the stiffened plates (penetrated and non-penetrated by fragments) are mainly conducted. The dynamic response rules of stiffened plates with holes under shock waves and fragments loading are obtained. The results show that the penetration of fragments into stiffened plates hardly affects their deformation produced by shock waves.

  3. Dynamic Response of Offshore Wind Turbines subjected to Joint Wave and Wind Loads

    DEFF Research Database (Denmark)

    Liu, Weiliang; Chen, Jianbing; Liu, Wenfeng;

    2013-01-01

    into consideration. Wind and wave loads are generated by the physical random models. The aerodynamic loads on blades are calculated by the Blade Element Momentum (BEM) theory, and the wave loads are calculated by the linear theory of wave. The dynamic response of the NREL-5MW wind turbine system is carried out......This paper investigates the dynamic response of offshore wind turbine systems subjected joint wind and wave loads. Relying on the finite element model, Kane’s equation is adopted to consider the rotation of blades. Besides, the generator-torque control and blade-pitch control are taken...

  4. Analyses of the seismic responses of soil layers with deep deposits

    Institute of Scientific and Technical Information of China (English)

    LOU Menglin; LI Yuchun; LI Nansheng

    2007-01-01

    Several typical problems in the seismic response analysis of soil layers with deep deposits have been studied according to the seismic response analysis of the soil layer in the Shanghai region. The problems include the effect of the inclination of the bedrock under the soil layer on the seismic responses of the soil layer, the rationality of the artificial horizontal bedrock boundary in the soil layer, and the effect of the wave velocity of the bedrock and dynamic characteris- tics of the soil media on the seismic responses of the soil layer. Some results are obtained by numerical analysis. In the seismic response analysis, the effect of angle of inclination of the rock surface under the soil layer can be neglected if the angle is not more than two degrees. A significant error will be introduced in the calculation when the artificial horizontal rock surface is assumed in the soil layer according to the shear velocity of the soil media. The elasticity of the solid rock has little influence on the seismic response of the deep soil layer. The field investigation on the soil dynamic property should be paid more attention to.

  5. Are Gene Expression Microarray Analyses Reliable? A Review of Studies of Retinoic Acid Responsive Genes

    Institute of Scientific and Technical Information of China (English)

    PeterJ.vanderSpek; AndreasKremer; LynnMurry; MichaelG.Walker

    2003-01-01

    Microarray analyses of gene expression are widely used,but reports of the same analyses by different groups give widely divergent results,and raise questions regarding reproducibility and reliability.We take as an example recent published reports on microarray experiments that were designed to identify retinoic acid responsive genes.These reports show substantial differences in their results.In this article,we review the methodology,results,and potential causes of differences in these applications of microarrays.Finally,we suggest practices to improve the reliability and reproducibility of microarray experiments.

  6. Are Gene Expression Microarray Analyses Reliable? A Review of Studies of Retinoic Acid Responsive Genes

    Institute of Scientific and Technical Information of China (English)

    Peter J. van der Spek; Andreas Kremer; Lynn Murry; Michael G. Walker

    2003-01-01

    Microarray analyses of gene expression are widely used, but reports of the same analyses by different groups give widely divergent results, and raise questions regarding reproducibility and reliability. We take as an example recent published reports on microarray experiments that were designed to identify retinoic acid responsive genes. These reports show substantial differences in their results. In this article, we review the methodology, results, and potential causes of differences in these applications of microarrays. Finally, we suggest practices to improve the reliability and reproducibility of microarray experiments.

  7. Variable salinity responses of 12 alfalfa genotypes and comparative expression analyses of salt-response genes

    Science.gov (United States)

    Sandhu, Devinder; Cornacchione, Monica V.; Ferreira, Jorge F. S.; Suarez, Donald L.

    2017-01-01

    Twelve alfalfa genotypes that were selected for biomass under salinity, differences in Na and Cl concentrations in shoots and K/Na ratio were evaluated in this long-term salinity experiment. The selected plants were cloned to reduce genetic variability within each genotype. Salt tolerance (ST) index of the genotypes ranged from 0.39 to 1. The most salt-tolerant genotypes SISA14-1 (G03) and AZ-90ST (G10), the top performers for biomass, exhibited the least effect on shoot number and height. SISA14-1 (G03) accumulated low Na and Cl under salinity. Most genotypes exhibited a net reduction in shoot Ca, Mg, P, Fe, and Cu, while Mn and Zn increased under salinity. Salinity reduced foliar area and stomatal conductance; while net photosynthetic rate and transpiration were not affected. Interestingly, salinity increased chlorophyll and antioxidant capacity in most genotypes; however neither parameter correlated well to ST index. Salt-tolerant genotypes showed upregulation of the SOS1, SOS2, SOS3, HKT1, AKT1, NHX1, P5CS1, HSP90.7, HSP81.2, HSP71.1, HSPC025, OTS1, SGF29 and SAL1 genes. Gene expression analyses allowed us to classify genotypes based on their ability to regulate different components of the salt tolerance mechanism. Pyramiding different components of the salt tolerance mechanism may lead to superior salt-tolerant alfalfa genotypes. PMID:28225027

  8. Site response, shallow shear-wave velocity, and wave propagation at the San Jose, California, dense seismic array

    Science.gov (United States)

    Hartzell, S.; Carver, D.; Williams, R.A.; Harmsen, S.; Zerva, A.

    2003-01-01

    Ground-motion records from a 52-element dense seismic array near San Jose, California, are analyzed to obtain site response, shallow shear-wave velocity, and plane-wave propagation characteristics. The array, located on the eastern side of the Santa Clara Valley south of the San Francisco Bay, is sited over the Evergreen basin, a 7-km-deep depression with Miocene and younger deposits. Site response values below 4 Hz are up to a factor of 2 greater when larger, regional records are included in the analysis, due to strong surface-wave development within the Santa Clara Valley. The pattern of site amplification is the same, however, with local or regional events. Site amplification increases away from the eastern edge of the Santa Clara Valley, reaching a maximum over the western edge of the Evergreen basin, where the pre-Cenozoic basement shallows rapidly. Amplification then decreases further to the west. This pattern may be caused by lower shallow shear-wave velocities and thicker Quaternary deposits further from the edge of the Santa Clara Valley and generation/trapping of surface waves above the shallowing basement of the western Evergreen basin. Shear-wave velocities from the inversion of site response spectra based on smaller, local earthquakes compare well with those obtained independently from our seismic reflection/refraction measurements. Velocities from the inversion of site spectra that include larger, regional records do not compare well with these measurements. A mix of local and regional events, however, is appropriate for determination of site response to be used in seismic hazard evaluation, since large damaging events would excite both body and surface waves with a wide range in ray parameters. Frequency-wavenumber, plane-wave analysis is used to determine the backazimuth and apparent velocity of coherent phases at the array. Conventional, high-resolution, and multiple signal characterization f-k power spectra and stacked slowness power spectra are

  9. Biomechanical and Biochemical Cellular Response Due to Shock Waves

    Science.gov (United States)

    2008-12-01

    using shock- wave-induced cavitation . Ultrasound in Medicine and Biology, 29, 1769-1776. Lew, H. L., J. H. Poole, S. Alvarez, and W. Moore, 2005...sheets of adipose derived stem cells to shock waves. A key guideline in the experimental design was to suppress cavitation . To this end we...shock-exposed cells and controls. We attribute this to the absence of cavitation . Time-resolved gene expression revealed that a large

  10. Lateralization of travelling wave response in the hearing organ of bushcrickets.

    Directory of Open Access Journals (Sweden)

    Arun Palghat Udayashankar

    Full Text Available Travelling waves are the physical basis of frequency discrimination in many vertebrate and invertebrate taxa, including mammals, birds, and some insects. In bushcrickets (Tettigoniidae, the crista acustica is the hearing organ that has been shown to use sound-induced travelling waves. Up to now, data on mechanical characteristics of sound-induced travelling waves were only available along the longitudinal (proximal-distal direction. In this study, we use laser Doppler vibrometry to investigate in-vivo radial (anterior-posterior features of travelling waves in the tropical bushcricket Mecopoda elongata. Our results demonstrate that the maximum of sound-induced travelling wave amplitude response is always shifted towards the anterior part of the crista acustica. This lateralization of the travelling wave response induces a tilt in the motion of the crista acustica, which presumably optimizes sensory transduction by exerting a shear motion on the sensory cilia in this hearing organ.

  11. Lateralization of travelling wave response in the hearing organ of bushcrickets.

    Science.gov (United States)

    Palghat Udayashankar, Arun; Kössl, Manfred; Nowotny, Manuela

    2014-01-01

    Travelling waves are the physical basis of frequency discrimination in many vertebrate and invertebrate taxa, including mammals, birds, and some insects. In bushcrickets (Tettigoniidae), the crista acustica is the hearing organ that has been shown to use sound-induced travelling waves. Up to now, data on mechanical characteristics of sound-induced travelling waves were only available along the longitudinal (proximal-distal) direction. In this study, we use laser Doppler vibrometry to investigate in-vivo radial (anterior-posterior) features of travelling waves in the tropical bushcricket Mecopoda elongata. Our results demonstrate that the maximum of sound-induced travelling wave amplitude response is always shifted towards the anterior part of the crista acustica. This lateralization of the travelling wave response induces a tilt in the motion of the crista acustica, which presumably optimizes sensory transduction by exerting a shear motion on the sensory cilia in this hearing organ.

  12. Resonant response of a strong electromagnetic wave beam to a gravitational wave in a static magnetic field

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    Concrete forms of resonant response (ER) for a strongelectromagnetic (EM) wave beam (photon flux) propagating in a static magnetic field to a standing gravitational wave (gravitons) are given, and the corresponding perturbation solutions and resonant conditions are obtained. It is found that perturbed EM fields (PEMFs) contain three new components with frequencies |ωg±ωe| and ωg, respectively. In the case of ωeωg, the PEMFs are manifested as the EM wave beams with frequency ωe and a standing EM wave with ωg. The former and the background EM wave beam (BEMWB) have the same propagating direction, while in the case of ωgωe, all PEMFs are expressed as the standing EM waves with frequency ωg. The resonant response occurs in two cases of ωe=1/2ωg and ωe=ωg only. Then not only the first order perturbed energy fluxes (PEFs) propagating in the same and opposite directions of the BEMWB can be generated, but also radial and tangential PEFs which are perpendicular to the above directions can be produced. This effect might provide a new way for the EM detection of the gravitational waves (GWs). Moreover, the possible schemes of displaying perturbed effects induced by the standing GW with h=10-33-10-35 and λg=0.1 m at the level of the single photon avalanche and in a typicla laboratory dimension are reviewed.

  13. How sex- and age-disaggregated data and gender and generational analyses can improve humanitarian response.

    Science.gov (United States)

    Mazurana, Dyan; Benelli, Prisca; Walker, Peter

    2013-07-01

    Humanitarian aid remains largely driven by anecdote rather than by evidence. The contemporary humanitarian system has significant weaknesses with regard to data collection, analysis, and action at all stages of response to crises involving armed conflict or natural disaster. This paper argues that humanitarian actors can best determine and respond to vulnerabilities and needs if they use sex- and age-disaggregated data (SADD) and gender and generational analyses to help shape their assessments of crises-affected populations. Through case studies, the paper shows how gaps in information on sex and age limit the effectiveness of humanitarian response in all phases of a crisis. The case studies serve to show how proper collection, use, and analysis of SADD enable operational agencies to deliver assistance more effectively and efficiently. The evidence suggests that the employment of SADD and gender and generational analyses assists in saving lives and livelihoods in a crisis.

  14. Intercomparison of fast response commercial gas analysers for nitrous oxide flux measurements under field conditions

    Science.gov (United States)

    Rannik, Ü.; Haapanala, S.; Shurpali, N. J.; Mammarella, I.; Lind, S.; Hyvönen, N.; Peltola, O.; Zahniser, M.; Martikainen, P. J.; Vesala, T.

    2015-01-01

    Four gas analysers capable of measuring nitrous oxide (N2O) concentration at a response time necessary for eddy covariance flux measurements were operated from spring until winter 2011 over a field cultivated with reed canary grass (RCG, Phalaris arundinacea, L.), a perennial bioenergy crop in eastern Finland. The instruments were TGA100A (Campbell Scientific Inc.), CW-TILDAS-CS (Aerodyne Research Inc.), N2O / CO-23d (Los Gatos Research Inc.) and QC-TILDAS-76-CS (Aerodyne Research Inc.). The period with high emissions, lasting for about 2 weeks after fertilization in late May, was characterized by an up to 2 orders of magnitude higher emission, whereas during the rest of the campaign the N2O fluxes were small, from 0.01 to 1 nmol m-2 s-1. Two instruments, CW-TILDAS-CS and N2O / CO-23d, determined the N2O exchange with minor systematic difference throughout the campaign, when operated simultaneously. TGA100A produced the cumulatively highest N2O estimates (with 29% higher values during the period when all instruments were operational). QC-TILDAS-76-CS obtained 36% lower fluxes than CW-TILDAS-CS during the first period, including the emission episode, whereas the correspondence with other instruments during the rest of the campaign was good. The reasons for systematic differences were not identified, suggesting further need for detailed evaluation of instrument performance under field conditions with emphasis on stability, calibration and any other factors that can systematically affect the accuracy of flux measurements. The instrument CW-TILDAS-CS was characterized by the lowest noise level (with a standard deviation of around 0.12 ppb at 10 Hz sampling rate) as compared to N2O / CO-23d and QC-TILDAS-76-CS (around 0.50 ppb) and TGA100A (around 2 ppb). We identified that for all instruments except CW-TILDAS-CS the random error due to instrumental noise was an important source of uncertainty at the 30 min averaging level and the total stochastic error was frequently

  15. Laminate Analyses, Micromechanical Creep Response, and Fatigue Behavior of Polymer Matrix Composite Materials.

    Science.gov (United States)

    1982-12-01

    FATIGUE BEHAVIOR of POLYMER MATRIX COMPOSITE MATERIALS , 4 " .’* .. . . ". ... .. ... . . ~December 1982 41 .. FINAL REPORT .Army Research Office I I...DEPARTMENT REPORT UWME-DR-201-108-1 LAMINATE ANALYSES, MICROMECHANICAL CREEP RESPONSE, AND FATIGUE BEHAVIOR OF POLYMER MATRIX COMPOSITE MATERIALS...Behavior of Polymer Matrix Composite 16 Sept. 1979 - 30 Nov. 1982 Materials 6 PERFORMING ORG. REPORT NUMBER UWME-DR-201-108-1 7. AUTHOR(.) S. CONTRACT

  16. Analysing task design and students' responses to context-based problems through different analytical frameworks

    Science.gov (United States)

    Broman, Karolina; Bernholt, Sascha; Parchmann, Ilka

    2015-05-01

    Background:Context-based learning approaches are used to enhance students' interest in, and knowledge about, science. According to different empirical studies, students' interest is improved by applying these more non-conventional approaches, while effects on learning outcomes are less coherent. Hence, further insights are needed into the structure of context-based problems in comparison to traditional problems, and into students' problem-solving strategies. Therefore, a suitable framework is necessary, both for the analysis of tasks and strategies. Purpose:The aim of this paper is to explore traditional and context-based tasks as well as students' responses to exemplary tasks to identify a suitable framework for future design and analyses of context-based problems. The paper discusses different established frameworks and applies the Higher-Order Cognitive Skills/Lower-Order Cognitive Skills (HOCS/LOCS) taxonomy and the Model of Hierarchical Complexity in Chemistry (MHC-C) to analyse traditional tasks and students' responses. Sample:Upper secondary students (n=236) at the Natural Science Programme, i.e. possible future scientists, are investigated to explore learning outcomes when they solve chemistry tasks, both more conventional as well as context-based chemistry problems. Design and methods:A typical chemistry examination test has been analysed, first the test items in themselves (n=36), and thereafter 236 students' responses to one representative context-based problem. Content analysis using HOCS/LOCS and MHC-C frameworks has been applied to analyse both quantitative and qualitative data, allowing us to describe different problem-solving strategies. Results:The empirical results show that both frameworks are suitable to identify students' strategies, mainly focusing on recall of memorized facts when solving chemistry test items. Almost all test items were also assessing lower order thinking. The combination of frameworks with the chemistry syllabus has been

  17. Wave loads on offshore wind turbines: Accurate tools and structural response

    DEFF Research Database (Denmark)

    Bredmose, Henrik

    2014-01-01

    Can the design models for offshore wind turbine wave loads be improved? And how will that change the overall load picture? Core questions of the Wave Loads project which was finalised in 2013 with two PhD theses, response calculations for jackets and monopiles, a detailed set of experiments and a3D...

  18. Partial wave analyses of J/psi to gamma pi^+ pi^- and gamma pi^0 pi^0

    CERN Document Server

    Ablikim, M

    2006-01-01

    Results are presented on J/psi radiative decays to pi^+pi^- and pi^0pi^0 based on a sample of 58M J/psi events taken with the BESII detector. Partial wave analyses are carried out using the relativistic covariant tensor amplitude method in the 1.0 to 2.3 GeV/c^2 pipi mass range. There are conspicuous peaks due to the f_2(1270) and two 0^++ states in the 1.45 and 1.75 GeV/c^2 mass regions. The first 0^++ state has a mass of 1466\\pm 6\\pm 20 MeV/c^2, a width of 108^{+14}_{-11}\\pm 21 MeV/c^2, and a branching fraction B(J/psi \\to \\gamma f_0(1500) \\to\\gamma \\pi^+\\pi^-) = (0.67\\pm0.02\\pm0.28) \\times 10^{-4}. Spin 0 is strongly preferred over spin 2. The second 0^++ state peaks at 1765^{+4}_{-3}\\pm 12 MeV/c^2 with a width of 145\\pm8\\pm69 MeV/c^2. If this 0^++ is interpreted as coming from f_0(1710), the ratio of its branching fractions to pipi and K\\bar K is 0.41^{+0.11}_{-0.17}.

  19. Linear theory of the response of Na mixing ratio to gravity waves

    Institute of Scientific and Technical Information of China (English)

    XU Jiyao; JI Qiao; WU Mingliang

    2003-01-01

    The influence of gravity waves on the sodium layer is studied by using a linear photochemical-dynamical coupling gravity wave model. The model includes the background photochemistry and the photochemical reactions in the sodium layer. The amplitude and phase difference of the response of sodium mixing ratio to gravity waves are calculated. The results indicate that the lower part of sodium layer is the most sensitive region responding to gravity waves. The perturbation of sodium mixing ratio is in phase with temperature in the lower part of the layer. However, it is out of phase with temperature fluctuation in the upper part.

  20. Wave propagation and site response in the Santa Clara Valley

    Science.gov (United States)

    Fletcher, Joe B.; Boatwright, J.; Lindh, A.G.

    2003-01-01

    Forty-two portable digital instruments were deployed across the Santa Clara Valley from June until early November 1998; this array recorded 14 small and moderate local events and 7 large teleseismic events. We analyze the ground motion from these events to determine station delays and relative site amplification within the Valley. P waves from an event at the southern edge of the valley are early (??t > -0.35 sec) at stations over an axial ridge in the basement interface in the middle of the valley, but late (??t < 0.20 sec) for stations over the Cupertino and Evergreen basins to either side. The S-wave delays are approximately twice as large. Teleseismic P-waves from an M = 7.0 event beneath the Bonin Islands show a similar pattern in travel-time delays. The P waves are amplified by factors of 1.5-3 for frequencies below 2 Hz at stations within either basin, compared with stations on the axial ridge. The P-wave coda appear enhanced at 2-3 sec, but coda Q estimates at frequencies from 0.2 to 1.1 Hz are not markedly different at stations over the basin compared with stations on the ridge with the possible exceptions of consistently high values over the northern end of the Evergreen Basin. We invert the S-wave spectra for site-specific attenuation and amplification from the 14 local events by assuming a common source spectra for each event, 1/r geometrical spreading, and constraining the inversion using the 30-m velocity profile at four stations in the array. The largest amplifications occurred in the 1- to 6-Hz band at stations near the northwest edge of the Evergreen basin. While the highest amplifications occur at stations with the lowest S-wave velocities, the scatter obscures the correlation between velocity and amplification. The stations in the basins are characterized by higher attenuation than the stations on the basement ridge.

  1. Numerical simulation of azimuth electromagnetic wave tool response based on self-adaptive FEM

    Science.gov (United States)

    Li, Hui; Shen, Yi-Ze

    2017-07-01

    Azimuth electromagnetic wave is a new type of electromagnetic prospecting technology. It can detect weak electromagnetic wave signal and realize real-time formation conductivity imaging. For effectively optimizing measurement accuracy of azimuth electromagnetic wave imaging tool, the efficient numerical simulation algorithm is required. In this paper, self-adaptive finite element method (FEM) has been used to investigate the azimuth electromagnetic wave logging tool response by adjusting antenna array system in different geological conditions. Numerical simulation examples show the accuracy and efficiency of the method, and provide physical interpretation of amplitude attenuation and phase shift of electromagnetic wave signal. Meanwhile, the high-accuracy numerical simulation results have great value to azimuth electromagnetic wave imaging tool calibration and data interpretation.

  2. A study on dynamic response of slopes under wave action using simulation tests

    Institute of Scientific and Technical Information of China (English)

    2003-01-01

    After the erection of the Three Gorges Dam, the water level of Yangtze River will reach 175 m, and the average wave crest will be up to 1 m. Therefore the wave action cannot be neglected for the slope stability. Through simulation tests, the waveinduced dynamic response of the slope is analyzed. The soil body is taken as linear elastic body when it has a small deformation under the small wave action. Based on tests, the excess pore pressure and slope displacement under the loading in different wave period are analyzed. The ratio of dynamic strength and static strength to the breaking process of the slope is discussed. It is demonstrated that smaller wave period gives rise to a larger strain of the slope under the same stress. At different depth of water, different weakness effect on the stability of the soil slope is observed and the slope has an adaptability to the wave action to some extent.

  3. Extreme Response Predictions for Jack-up Units in Second Order Stochastic Waves by FORM

    DEFF Research Database (Denmark)

    Jensen, Jørgen Juncher; Capul, Julien

    2006-01-01

    An efficient procedure for derivation of mean outcrossing rates for non-linear wave-induced responses in stationary sea states is presented and applied to an analysis of the horizontal deck sway of a jack-up unit. The procedure is based on the theory of random vibrations and uses the first order...... reliability method (FORM) to estimate the most probable set of wave components in the ocean wave system that will lead to exceedance of a specific response level together with the associated mean outcrossing rate. The procedure bears some resemblance to the Constrained NewWave methodology, but is conceptually......-tic waves, not previously included in the analysis of jack-up units in stochastic seaways....

  4. Investigation of the Air-Wave-Sea Interaction Modes Using an Airborne Doppler Wind Lidar: Analyses of the HRDL Data Taken using DYNAMO

    Science.gov (United States)

    2013-10-07

    Interaction Modes Using an Airborne Doppler Wind Lidar: Analyses of the HRDL data taken using DYNAMO 5a. CONTRACT NUMBER N0001411C0464 5b. GRANT...efficiency of energy, mass and momentum exchange at the bottom and top of the ABL. 15. SUBJECT TERMS DYNAMO , ABL 16. SECURITY CLASSIFICATION OF: 17...Investigation of the Air-Wave-Sea Interaction Modes Using an Airborne Doppler Wind Lidar: Analyses of the HRDL data taken during DYNAMO George

  5. Analytical Solution for Wave-Induced Response of Seabed with Variable Shear Modulus

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    A plane strain analysis based on the generalized Biot's equation is utilized to investigate the wave-induced response of a poro-elastic seabed with variable shear modulus. By employing integral transform and Frobenius methods, the transient and steady solutions for the wave-induced pore water pressure, effective stresses and displacements are analytically derived in detail. Verification is available through the reduction to the simple case of homogeneous seabed. The numerical results indicate that the inclusion of variable shear modulus significantly affects the wave-induced seabed response.

  6. Sources of uncertainty in eddy covariance ozone flux measurements made by dry chemiluminescence fast response analysers

    Directory of Open Access Journals (Sweden)

    J. B. A. Muller

    2009-09-01

    Full Text Available Eddy covariance ozone flux measurements are the most direct way to estimate ozone removal near the surface. Over vegetated surfaces, high quality ozone fluxes are required to probe the underlying processes for which it is necessary to separate the flux into the components of stomatal and non-stomatal deposition. Detailed knowledge of the processes that control non-stomatal deposition is limited and more accurate ozone flux measurements are needed to quantify this component of the deposited flux. We present a systematic intercomparison study of eddy covariance ozone flux measurements made using two fast response dry chemiluminescence analysers. Ozone deposition was measured over a well characterised managed grassland near Edinburgh, Scotland, during August 2007. A data quality control procedure specific to these analysers is introduced. Absolute ozone fluxes were calculated based on the relative signals of the dry chemiluminescence analysers using three different calibration methods and the results are compared for both analysers. It is shown that the error in the fitted parameters required for the flux calculations provides a substantial source of uncertainty in the fluxes. The choice of the calculation method itself can also constitute an uncertainty in the flux as the calculated fluxes by the three methods do not agree within error at all times. This finding highlights the need for a consistent and rigorous approach for comparable data-sets, such as e.g. in flux networks. Ozone fluxes calculated by one of the methods were then used to compare the two analysers in more detail. This systematic analyser comparison reveals half-hourly flux values differing by up to a factor of two at times with the difference in mean hourly flux ranging from 0 to 23% with an error in the mean daily flux of ±12%. The comparison of analysers shows that the agreement in fluxes is excellent for some days but that there is an underlying uncertainty as a result of

  7. Seismic response and damage detection analyses of an instrumented steel moment-framed building

    Science.gov (United States)

    Rodgers, J.E.; Celebi, M.

    2006-01-01

    The seismic performance of steel moment-framed buildings has been of particular interest since brittle fractures were discovered at the beam-column connections in a number of buildings following the M 6.7 Northridge earthquake of January 17, 1994. A case study of the seismic behavior of an extensively instrumented 13-story steel moment frame building located in the greater Los Angeles area of California is described herein. Response studies using frequency domain, joint time-frequency, system identification, and simple damage detection analyses are performed using an extensive strong motion dataset dating from 1971 to the present, supported by engineering drawings and results of postearthquake inspections. These studies show that the building's response is more complex than would be expected from its highly symmetrical geometry. The response is characterized by low damping in the fundamental mode, larger accelerations in the middle and lower stories than at the roof and base, extended periods of vibration after the cessation of strong input shaking, beating in the response, elliptical particle motion, and significant torsion during strong shaking at the top of the concrete piers which extend from the basement to the second floor. The analyses conducted indicate that the response of the structure was elastic in all recorded earthquakes to date, including Northridge. Also, several simple damage detection methods employed did not indicate any structural damage or connection fractures. The combination of a large, real structure and low instrumentation density precluded the application of many recently proposed advanced damage detection methods in this case study. Overall, however, the findings of this study are consistent with the limited code-compliant postearthquake intrusive inspections conducted after the Northridge earthquake, which found no connection fractures or other structural damage. ?? ASCE.

  8. Physiological and transcriptomic analyses reveal a response mechanism to cold stress in Santalum album L. leaves

    Science.gov (United States)

    Zhang, Xinhua; Teixeira da Silva, Jaime A.; Niu, Meiyun; Li, Mingzhi; He, Chunmei; Zhao, Jinhui; Zeng, Songjun; Duan, Jun; Ma, Guohua

    2017-01-01

    Santalum album L. (Indian sandalwood) is an economically important plant species because of its ability to produce highly valued perfume oils. Little is known about the mechanisms by which S. album adapts to low temperatures. In this study, we obtained 100,445,724 raw reads by paired-end sequencing from S. album leaves. Physiological and transcriptomic changes in sandalwood seedlings exposed to 4 °C for 0–48 h were characterized. Cold stress induced the accumulation of malondialdehyde, proline and soluble carbohydrates, and increased the levels of antioxidants. A total of 4,424 differentially expressed genes were responsive to cold, including 3,075 cold-induced and 1,349 cold-repressed genes. When cold stress was prolonged, there was an increase in the expression of cold-responsive genes coding for transporters, responses to stimuli and stress, regulation of defense response, as well as genes related to signal transduction of all phytohormones. Candidate genes in the terpenoid biosynthetic pathway were identified, eight of which were significantly involved in the cold stress response. Gene expression analyses using qRT-PCR showed a peak in the accumulation of SaCBF2 to 4, 50-fold more than control leaves and roots following 12 h and 24 h of cold stress, respectively. The CBF-dependent pathway may play a crucial role in increasing cold tolerance. PMID:28169358

  9. Metabolic and co-expression network-based analyses associated with nitrate response in rice.

    Science.gov (United States)

    Coneva, Viktoriya; Simopoulos, Caitlin; Casaretto, José A; El-Kereamy, Ashraf; Guevara, David R; Cohn, Jonathan; Zhu, Tong; Guo, Lining; Alexander, Danny C; Bi, Yong-Mei; McNicholas, Paul D; Rothstein, Steven J

    2014-12-03

    Understanding gene expression and metabolic re-programming that occur in response to limiting nitrogen (N) conditions in crop plants is crucial for the ongoing progress towards the development of varieties with improved nitrogen use efficiency (NUE). To unravel new details on the molecular and metabolic responses to N availability in a major food crop, we conducted analyses on a weighted gene co-expression network and metabolic profile data obtained from leaves and roots of rice plants adapted to sufficient and limiting N as well as after shifting them to limiting (reduction) and sufficient (induction) N conditions. A gene co-expression network representing clusters of rice genes with similar expression patterns across four nitrogen conditions and two tissue types was generated. The resulting 18 clusters were analyzed for enrichment of significant gene ontology (GO) terms. Four clusters exhibited significant correlation with limiting and reducing nitrate treatments. Among the identified enriched GO terms, those related to nucleoside/nucleotide, purine and ATP binding, defense response, sugar/carbohydrate binding, protein kinase activities, cell-death and cell wall enzymatic activity are enriched. Although a subset of functional categories are more broadly associated with the response of rice organs to limiting N and N reduction, our analyses suggest that N reduction elicits a response distinguishable from that to adaptation to limiting N, particularly in leaves. This observation is further supported by metabolic profiling which shows that several compounds in leaves change proportionally to the nitrate level (i.e. higher in sufficient N vs. limiting N) and respond with even higher levels when the nitrate level is reduced. Notably, these compounds are directly involved in N assimilation, transport, and storage (glutamine, asparagine, glutamate and allantoin) and extend to most amino acids. Based on these data, we hypothesize that plants respond by rapidly mobilizing

  10. The link between genetic variation and variability in vaccine responses: systematic review and meta-analyses.

    Science.gov (United States)

    Posteraro, Brunella; Pastorino, Roberta; Di Giannantonio, Paolo; Ianuale, Carolina; Amore, Rosarita; Ricciardi, Walter; Boccia, Stefania

    2014-03-26

    Although immune response to vaccines can be influenced by several parameters, human genetic variations are thought to strongly influence the variability in vaccine responsiveness. Systematic reviews and meta-analyses are needed to clarify the genetic contribution to this variability, which may affect the efficacy of existing vaccines. We performed a systematic literature search to identify all studies describing the associations of allelic variants or single nucleotide polymorphisms in immune response genes with vaccine responses until July 2013. The studies fulfilling inclusion criteria were meta-analyzed. Thirteen studies (11,686 subjects) evaluated the associations of human leukocyte antigen (HLA) and other immunity gene variations with the responses to single vaccines, including MMR-II (measles and rubella virus), HepB (hepatitis virus), influenza virus, and MenC (serogroup C meningococcus) vaccines. Seven HLA genetic variants were included in the meta-analyses. The pooled ORs showed that DRB1*07 (2.46 [95% CI=1.60-3.77]; P for heterogeneity=0.117; I(2)=49.1%), DQA1*02:01 (2.21 [95% CI=1.22-4.00]; P for heterogeneity=0.995; I(2)=0.0%), DQB1*02:01 (2.03 [95% CI=1.35-3.07]; P for heterogeneity=0.449; I(2)=0.0%), and DQB1*03:03 (3.31 [95% CI=1.12-9.78]; P for heterogeneity=0.188; I(2)=42.4%) were associated with a significant decrease of antibody responses to MMR-II, HepB, and influenza vaccines. The pooled ORs showed that DRB1*13 (0.52 [95% CI=0.32-0.84]; P for heterogeneity=0.001; I(2)=85.1%) and DRB1*13:01 (0.19 [95% CI=0.06-0.58]; P for heterogeneity=0.367; I(2)=0.0%) were associated with a significant increase of antibody responses to the above vaccines. While our findings reinforce the concept that individuals with a particular HLA allelic composition are more likely to respond efficiently to vaccines, future studies should be encouraged to further elucidate the link between genetic variation and variability of the human immune response to vaccines

  11. Response of ocean bottom dwellers exposed to underwater shock waves

    Science.gov (United States)

    Hosseini, S. H. R.; Kaiho, Kunio; Takayama, Kazuyoshi

    2016-01-01

    The paper reports results of experiments to estimate the mortality of ocean bottom dwellers, ostracoda, against underwater shock wave exposures. This study is motivated to verify the possible survival of ocean bottom dwellers, foraminifera, from the devastating underwater shock waves induced mass extinction of marine creatures which took place at giant asteroid impact events. Ocean bottom dwellers under study were ostracoda, the replacement of foraminifera, we readily sampled from ocean bottoms. An analogue experiment was performed on a laboratory scale to estimate the domain and boundary of over-pressures at which marine creatures' mortality occurs. Ostracods were exposed to underwater shock waves generated by the explosion of 100mg PETN pellets in a chamber at shock over-pressures ranging up to 44MPa. Pressure histories were measured simultaneously on 113 samples. We found that bottom dwellers were distinctively killed against overpressures of 12MPa and this value is much higher than the usual shock over-pressure threshold value for marine-creatures having lungs and balloons.

  12. Response spectrum method for extreme wave loading with higher order components of drag force

    Science.gov (United States)

    Reza, Tabeshpour Mohammad; Mani, Fatemi Dezfouli; Mohammad Ali, Dastan Diznab; Saied, Mohajernasab; Saied, Seif Mohammad

    2017-01-01

    Response spectra of fixed offshore structures impacted by extreme waves are investigated based on the higher order components of the nonlinear drag force. In this way, steel jacket platforms are simplified as a mass attached to a light cantilever cylinder and their corresponding deformation response spectra are estimated by utilizing a generalized single degree of freedom system. Based on the wave data recorded in the Persian Gulf region, extreme wave loading conditions corresponding to different return periods are exerted on the offshore structures. Accordingly, the effect of the higher order components of the drag force is considered and compared to the linearized state for different sea surface levels. When the fundamental period of the offshore structure is about one third of the main period of wave loading, the results indicate the linearized drag term is not capable of achieving a reliable deformation response spectrum.

  13. Flutter and Forced Response Analyses of Cascades using a Two-Dimensional Linearized Euler Solver

    Science.gov (United States)

    Reddy, T. S. R.; Srivastava, R.; Mehmed, O.

    1999-01-01

    Flutter and forced response analyses for a cascade of blades in subsonic and transonic flow is presented. The structural model for each blade is a typical section with bending and torsion degrees of freedom. The unsteady aerodynamic forces due to bending and torsion motions. and due to a vortical gust disturbance are obtained by solving unsteady linearized Euler equations. The unsteady linearized equations are obtained by linearizing the unsteady nonlinear equations about the steady flow. The predicted unsteady aerodynamic forces include the effect of steady aerodynamic loading due to airfoil shape, thickness and angle of attack. The aeroelastic equations are solved in the frequency domain by coupling the un- steady aerodynamic forces to the aeroelastic solver MISER. The present unsteady aerodynamic solver showed good correlation with published results for both flutter and forced response predictions. Further improvements are required to use the unsteady aerodynamic solver in a design cycle.

  14. Using complexity theory to analyse the organisational response to resurgent tuberculosis across London.

    Science.gov (United States)

    Trenholm, Susan; Ferlie, Ewan

    2013-09-01

    We employ complexity theory to analyse the English National Health Service (NHS)'s organisational response to resurgent tuberculosis across London. Tennison (2002) suggests that complexity theory could fruitfully explore a healthcare system's response to this complex and emergent phenomenon: we explore this claim here. We also bring in established New Public Management principles to enhance our empirical analysis, which is based on data collected between late 2009 and mid-2011. We find that the operation of complexity theory based features, especially self-organisation, are significantly impacted by the macro context of a New Public Management-based regime which values control, measurement and risk management more than innovation, flexibility and lateral system building. We finally explore limitations and suggest perspectives for further research.

  15. Mediational Analyses of the Effects of Responsive Teaching on the Developmental Functioning of Preschool Children with Disabilities

    Science.gov (United States)

    Karaaslan, Ozcan; Mahoney, Gerald

    2015-01-01

    Mediational analyses were conducted with data from two small randomized control trials of the Responsive Teaching (RT) parent-mediated developmental intervention which used nearly identical intervention and control procedures. The purpose of these analyses was to determine whether or how the changes in maternal responsiveness and children's…

  16. The stimulus-evoked population response in visual cortex of awake monkey is a propagating wave.

    Science.gov (United States)

    Muller, Lyle; Reynaud, Alexandre; Chavane, Frédéric; Destexhe, Alain

    2014-04-28

    Propagating waves occur in many excitable media and were recently found in neural systems from retina to neocortex. While propagating waves are clearly present under anaesthesia, whether they also appear during awake and conscious states remains unclear. One possibility is that these waves are systematically missed in trial-averaged data, due to variability. Here we present a method for detecting propagating waves in noisy multichannel recordings. Applying this method to single-trial voltage-sensitive dye imaging data, we show that the stimulus-evoked population response in primary visual cortex of the awake monkey propagates as a travelling wave, with consistent dynamics across trials. A network model suggests that this reliability is the hallmark of the horizontal fibre network of superficial cortical layers. Propagating waves with similar properties occur independently in secondary visual cortex, but maintain precise phase relations with the waves in primary visual cortex. These results show that, in response to a visual stimulus, propagating waves are systematically evoked in several visual areas, generating a consistent spatiotemporal frame for further neuronal interactions.

  17. The Northern Hemisphere winter stationary wave response to global warming in CMIP5

    Science.gov (United States)

    Simpson, Isla; Seager, Richard; Ting, Mingfang; Shaw, Tiffany

    2015-04-01

    During the Northern Hemisphere winter, models tend to predict a poleward shifting of the zonal mean mid-latitude westerlies under anthropogenic greenhouse gas emissions. Locally, however, changes in the stationary waves tend to dominate, resulting in considerable deviation from this around the longitude circle, with important implications for regional climate change. Past studies have demonstrated diversity in the stationary wave response to global warming and differ in their views of the mechanisms involved in producing it. Here we will explore the stationary wave response to global warming in the CMIP5 dataset and demonstrate a strong consensus on a wavenumber 5 stationary wave response with a particular phasing that contributes to hydroclimate change across North America and Europe, such as wetting on the west coast of the USA, drying in the south west USA and drying in the eastern Mediterranean. The mechanisms responsible for producing this multi-model mean response are explored using a stationary wave model. It is demonstrated that, to first order, it is produced by changes in the zonal mean basic state, in agreement with the majority of previous stationary wave modelling studies. The relative importance of different features of this basic state change such as Arctic amplification, enhanced tropical upper tropospheric warming, stratospheric cooling and their associated zonal mean zonal wind responses will be explored. Through an understanding of the mechanisms involved in this stationary wave response we can begin to assess our confidence in whether the real world will behave as the models do and understand any diversity among the modelled responses.

  18. Responses of Waveform-Selective Absorbing Metasurfaces to Oblique Waves at the Same Frequency.

    Science.gov (United States)

    Wakatsuchi, Hiroki; Gao, Fei; Yagitani, Satoshi; Sievenpiper, Daniel F

    2016-08-12

    Conventional materials vary their electromagnetic properties in response to the frequency of an incoming wave, but these responses generally remain unchanged at the same frequency unless nonlinearity is involved. Waveform-selective metasurfaces, recently developed by integrating several circuit elements with planar subwavelength periodic structures, allowed us to distinguish different waves even at the same frequency depending on how long the waves continued, namely, on their pulse widths. These materials were thus expected to give us an additional degree of freedom to control electromagnetic waves. However, all the past studies were demonstrated with waves at a normal angle only, although in reality electromagnetic waves scatter from various structures or boundaries and therefore illuminate the metasurfaces at oblique angles. Here we study angular dependences of waveform-selective metasurfaces both numerically and experimentally. We demonstrate that, if designed properly, capacitor-based waveform-selective metasurfaces more effectively absorb short pulses than continuous waves (CWs) for a wide range of the incident angle, while inductor-based metasurfaces absorb CWs more strongly. Our study is expected to be usefully exploited for applying the concept of waveform selectivity to a wide range of existing microwave devices to expand their functionalities or performances in response to pulse width as a new capability.

  19. Item response theory analyses of the Cambridge Face Memory Test (CFMT).

    Science.gov (United States)

    Cho, Sun-Joo; Wilmer, Jeremy; Herzmann, Grit; McGugin, Rankin Williams; Fiset, Daniel; Van Gulick, Ana E; Ryan, Kaitlin F; Gauthier, Isabel

    2015-06-01

    We evaluated the psychometric properties of the Cambridge Face Memory Test (CFMT; Duchaine & Nakayama, 2006). First, we assessed the dimensionality of the test with a bifactor exploratory factor analysis (EFA). This EFA analysis revealed a general factor and 3 specific factors clustered by targets of CFMT. However, the 3 specific factors appeared to be minor factors that can be ignored. Second, we fit a unidimensional item response model. This item response model showed that the CFMT items could discriminate individuals at different ability levels and covered a wide range of the ability continuum. We found the CFMT to be particularly precise for a wide range of ability levels. Third, we implemented item response theory (IRT) differential item functioning (DIF) analyses for each gender group and 2 age groups (age ≤ 20 vs. age > 21). This DIF analysis suggested little evidence of consequential differential functioning on the CFMT for these groups, supporting the use of the test to compare older to younger, or male to female, individuals. Fourth, we tested for a gender difference on the latent facial recognition ability with an explanatory item response model. We found a significant but small gender difference on the latent ability for face recognition, which was higher for women than men by 0.184, at age mean 23.2, controlling for linear and quadratic age effects. Finally, we discuss the practical considerations of the use of total scores versus IRT scale scores in applications of the CFMT.

  20. Global transcriptional, physiological and metabolite analyses of Desulfovibrio vulgaris Hildenborough responses to salt adaptation

    Energy Technology Data Exchange (ETDEWEB)

    He, Z.; Zhou, A.; Baidoo, E.; He, Q.; Joachimiak, M. P.; Benke, P.; Phan, R.; Mukhopadhyay, A.; Hemme, C.L.; Huang, K.; Alm, E.J.; Fields, M.W.; Wall, J.; Stahl, D.; Hazen, T.C.; Keasling, J.D.; Arkin, A.P.; Zhou, J.

    2009-12-01

    The response of Desulfovibrio vulgaris Hildenborough to salt adaptation (long-term NaCl exposure) was examined by physiological, global transcriptional, and metabolite analyses. The growth of D. vulgaris was inhibited by high levels of NaCl, and the growth inhibition could be relieved by the addition of exogenous amino acids (e.g., glutamate, alanine, tryptophan) or yeast extract. Salt adaptation induced the expression of genes involved in amino acid biosynthesis and transport, electron transfer, hydrogen oxidation, and general stress responses (e.g., heat shock proteins, phage shock proteins, and oxidative stress response proteins). Genes involved in carbon metabolism, cell motility, and phage structures were repressed. Comparison of transcriptomic profiles of D. vulgaris responses to salt adaptation with those of salt shock (short-term NaCl exposure) showed some similarity as well as a significant difference. Metabolite assays showed that glutamate and alanine were accumulated under salt adaptation, suggesting that they may be used as osmoprotectants in D. vulgaris. A conceptual model is proposed to link the observed results to currently available knowledge for further understanding the mechanisms of D. vulgaris adaptation to elevated NaCl.

  1. Transcriptional and proteomic analyses of two-component response regulators in multidrug-resistant Mycobacterium tuberculosis.

    Science.gov (United States)

    Zhou, Lei; Yang, Liu; Zeng, Xianfei; Danzheng, Jiacuo; Zheng, Qing; Liu, Jiayun; Liu, Feng; Xin, Yijuan; Cheng, Xiaodong; Su, Mingquan; Ma, Yueyun; Hao, Xiaoke

    2015-07-01

    Two-component systems (TCSs) have been reported to exhibit a sensing and responding role under drug stress that induces drug resistance in several bacterial species. However, the relationship between TCSs and multidrug resistance in Mycobacterium tuberculosis has not been comprehensively analysed to date. In this study, 90 M. tuberculosis clinical isolates were analysed using 15-loci mycobacterial interspersed repetitive unit (MIRU)-variable number tandem repeat (VNTR) typing and repetitive extragenic palindromic (rep)-PCR-based DNA fingerprinting. The results showed that all of the isolates were of the Beijing lineage, and strains with a drug-susceptible phenotype had not diverged into similar genotype clusters. Expression analysis of 13 response regulators of TCSs using real-time PCR and tandem mass spectrometry (MS/MS) proteomic analysis demonstrated that four response regulator genes (devR, mtrA, regX3 and Rv3143) were significantly upregulated in multidrug-resistant (MDR) strains compared with the laboratory strain H37Rv as well as drug-susceptible and isoniazid-monoresistant strains (PMycobacterium bovis BCG did not alter its sensitivity to the four antitubercular drugs. This suggests that upregulation of devR, which is common in MDR-TB strains, might be induced by drug stress and hypoxic adaptation following the acquisition of multidrug resistance.

  2. Molecular responses of mouse macrophages to copper and copper oxide nanoparticles inferred from proteomic analyses.

    Science.gov (United States)

    Triboulet, Sarah; Aude-Garcia, Catherine; Carrière, Marie; Diemer, Hélène; Proamer, Fabienne; Habert, Aurélie; Chevallet, Mireille; Collin-Faure, Véronique; Strub, Jean-Marc; Hanau, Daniel; Van Dorsselaer, Alain; Herlin-Boime, Nathalie; Rabilloud, Thierry

    2013-11-01

    The molecular responses of macrophages to copper-based nanoparticles have been investigated via a combination of proteomic and biochemical approaches, using the RAW264.7 cell line as a model. Both metallic copper and copper oxide nanoparticles have been tested, with copper ion and zirconium oxide nanoparticles used as controls. Proteomic analysis highlighted changes in proteins implicated in oxidative stress responses (superoxide dismutases and peroxiredoxins), glutathione biosynthesis, the actomyosin cytoskeleton, and mitochondrial proteins (especially oxidative phosphorylation complex subunits). Validation studies employing functional analyses showed that the increases in glutathione biosynthesis and in mitochondrial complexes observed in the proteomic screen were critical to cell survival upon stress with copper-based nanoparticles; pharmacological inhibition of these two pathways enhanced cell vulnerability to copper-based nanoparticles, but not to copper ions. Furthermore, functional analyses using primary macrophages derived from bone marrow showed a decrease in reduced glutathione levels, a decrease in the mitochondrial transmembrane potential, and inhibition of phagocytosis and of lipopolysaccharide-induced nitric oxide production. However, only a fraction of these effects could be obtained with copper ions. In conclusion, this study showed that macrophage functions are significantly altered by copper-based nanoparticles. Also highlighted are the cellular pathways modulated by cells for survival and the exemplified cross-toxicities that can occur between copper-based nanoparticles and pharmacological agents.

  3. Molecular Responses of Mouse Macrophages to Copper and Copper Oxide Nanoparticles Inferred from Proteomic Analyses*

    Science.gov (United States)

    Triboulet, Sarah; Aude-Garcia, Catherine; Carrière, Marie; Diemer, Hélène; Proamer, Fabienne; Habert, Aurélie; Chevallet, Mireille; Collin-Faure, Véronique; Strub, Jean-Marc; Hanau, Daniel; Van Dorsselaer, Alain; Herlin-Boime, Nathalie; Rabilloud, Thierry

    2013-01-01

    The molecular responses of macrophages to copper-based nanoparticles have been investigated via a combination of proteomic and biochemical approaches, using the RAW264.7 cell line as a model. Both metallic copper and copper oxide nanoparticles have been tested, with copper ion and zirconium oxide nanoparticles used as controls. Proteomic analysis highlighted changes in proteins implicated in oxidative stress responses (superoxide dismutases and peroxiredoxins), glutathione biosynthesis, the actomyosin cytoskeleton, and mitochondrial proteins (especially oxidative phosphorylation complex subunits). Validation studies employing functional analyses showed that the increases in glutathione biosynthesis and in mitochondrial complexes observed in the proteomic screen were critical to cell survival upon stress with copper-based nanoparticles; pharmacological inhibition of these two pathways enhanced cell vulnerability to copper-based nanoparticles, but not to copper ions. Furthermore, functional analyses using primary macrophages derived from bone marrow showed a decrease in reduced glutathione levels, a decrease in the mitochondrial transmembrane potential, and inhibition of phagocytosis and of lipopolysaccharide-induced nitric oxide production. However, only a fraction of these effects could be obtained with copper ions. In conclusion, this study showed that macrophage functions are significantly altered by copper-based nanoparticles. Also highlighted are the cellular pathways modulated by cells for survival and the exemplified cross-toxicities that can occur between copper-based nanoparticles and pharmacological agents. PMID:23882024

  4. Application of the Most Likely Extreme Response Method for Wave Energy Converters: Preprint

    Energy Technology Data Exchange (ETDEWEB)

    Quon, Eliot; Platt, Andrew; Yu, Yi-Hsiang; Lawson, Michael

    2016-07-01

    Extreme loads are often a key cost driver for wave energy converters (WECs). As an alternative to exhaustive Monte Carlo or long-term simulations, the most likely extreme response (MLER) method allows mid- and high-fidelity simulations to be used more efficiently in evaluating WEC response to events at the edges of the design envelope, and is therefore applicable to system design analysis. The study discussed in this paper applies the MLER method to investigate the maximum heave, pitch, and surge force of a point absorber WEC. Most likely extreme waves were obtained from a set of wave statistics data based on spectral analysis and the response amplitude operators (RAOs) of the floating body; the RAOs were computed from a simple radiation-and-diffraction-theory-based numerical model. A weakly nonlinear numerical method and a computational fluid dynamics (CFD) method were then applied to compute the short-term response to the MLER wave. Effects of nonlinear wave and floating body interaction on the WEC under the anticipated 100-year waves were examined by comparing the results from the linearly superimposed RAOs, the weakly nonlinear model, and CFD simulations. Overall, the MLER method was successfully applied. In particular, when coupled to a high-fidelity CFD analysis, the nonlinear fluid dynamics can be readily captured.

  5. Application of the Most Likely Extreme Response Method for Wave Energy Converters

    Energy Technology Data Exchange (ETDEWEB)

    Quon, Eliot; Platt, Andrew; Yu, Yi-Hsiang; Lawson, Michael

    2016-06-24

    Extreme loads are often a key cost driver for wave energy converters (WECs). As an alternative to exhaustive Monte Carlo or long-term simulations, the most likely extreme response (MLER) method allows mid- and high-fidelity simulations to be used more efficiently in evaluating WEC response to events at the edges of the design envelope, and is therefore applicable to system design analysis. The study discussed in this paper applies the MLER method to investigate the maximum heave, pitch, and surge force of a point absorber WEC. Most likely extreme waves were obtained from a set of wave statistics data based on spectral analysis and the response amplitude operators (RAOs) of the floating body; the RAOs were computed from a simple radiation-and-diffraction-theory-based numerical model. A weakly nonlinear numerical method and a computational fluid dynamics (CFD) method were then applied to compute the short-term response to the MLER wave. Effects of nonlinear wave and floating body interaction on the WEC under the anticipated 100-year waves were examined by comparing the results from the linearly superimposed RAOs, the weakly nonlinear model, and CFD simulations. Overall, the MLER method was successfully applied. In particular, when coupled to a high-fidelity CFD analysis, the nonlinear fluid dynamics can be readily captured.

  6. Pulsed response of a traveling-wave tube

    Science.gov (United States)

    May, Brian D.

    1991-01-01

    The consequence of frequency-domain multiple access (FDMA) channelization in a satellite communications system is that the ground- and space-based components are often required to operate at reduced output power to prevent the generation of distortions. However, the components of a time-division multiple access (TDMA) satellite system, such as a traveling-wave tube (TWT), can operate at the highest output power because the channelization technique is relatively insensitive to the distortions resulting from saturated operation. A Hughes 30-GHz TWT was tested to determine the suitability of such a device in a TDMA system. Testing was focused on the ability of the TWT to rise up to full power at the leading edge of TDMA bursts, which were simulated by a pulse train. A Wavetek model 8502A peak power meter was used to display and measure the pulsed signal waveform. Measurements of the TWT output signal rise time indicate that the TWT lengthened the rise time by 10 to 20 nsec. Imposing a modulator turn-on time that precedes the data burst by the TWT rise time is a logical approach to coordinating the traveling-wave tube amplifier and modulator specifications.

  7. Response of surface buoy moorings in steady and wave flows

    Digital Repository Service at National Institute of Oceanography (India)

    Anand, N.M.; Nayak, B.U.; SanilKumar, V.

    as well as for shallow water moorings having three different damping ratios equal to 0.1, 0.2 and 0.3. In all cases considered, as the damping ratio increases the mean square tension response decreases. Tension response spectra of deep water mooring seem...

  8. Stochastic procedures for extreme wave induced responses in flexible ships

    DEFF Research Database (Denmark)

    Jensen, Jørgen Juncher; Andersen, Ingrid Marie Vincent; Seng, Sopheak

    2014-01-01

    estimation of extreme responses. Secondly, stochastic procedures using measured time series of responses as input are considered. The Peak-over-Threshold procedure and the Weibull fitting are applied and discussed for the extreme value predictions including possible corrections for clustering effects....

  9. Summed Parallel Infinite Impulse Response (SPIIR) Filters For Low-Latency Gravitational Wave Detection

    CERN Document Server

    Hooper, Shaun; Luan, Jing; Blair, David; Chen, Yanbei; Wen, Linqing

    2011-01-01

    With the upgrade of current gravitational wave detectors, the first detection of gravitational wave signals is expected to occur in the next decade. Low-latency gravitational wave triggers will be necessary to make fast follow-up electromagnetic observations of events related to their source, e.g., prompt optical emission associated with short gamma-ray bursts. In this paper we present a new time-domain low-latency algorithm for identifying the presence of gravitational waves produced by compact binary coalescence events in noisy detector data. Our method calculates the signal to noise ratio from the summation of a bank of parallel infinite impulse response (IIR) filters. We show that our summed parallel infinite impulse response (SPIIR) method can retrieve the signal to noise ratio to greater than 99% of that produced from the optimal matched filter. We emphasise the benefits of the SPIIR method for advanced detectors, which will require larger template banks.

  10. Rhythmic entrainment source separation: Optimizing analyses of neural responses to rhythmic sensory stimulation.

    Science.gov (United States)

    Cohen, Michael X; Gulbinaite, Rasa

    2017-02-15

    Steady-state evoked potentials (SSEPs) are rhythmic brain responses to rhythmic sensory stimulation, and are often used to study perceptual and attentional processes. We present a data analysis method for maximizing the signal-to-noise ratio of the narrow-band steady-state response in the frequency and time-frequency domains. The method, termed rhythmic entrainment source separation (RESS), is based on denoising source separation approaches that take advantage of the simultaneous but differential projection of neural activity to multiple electrodes or sensors. Our approach is a combination and extension of existing multivariate source separation methods. We demonstrate that RESS performs well on both simulated and empirical data, and outperforms conventional SSEP analysis methods based on selecting electrodes with the strongest SSEP response, as well as several other linear spatial filters. We also discuss the potential confound of overfitting, whereby the filter captures noise in absence of a signal. Matlab scripts are available to replicate and extend our simulations and methods. We conclude with some practical advice for optimizing SSEP data analyses and interpreting the results.

  11. Analysing and combining atmospheric general circulation model simulations forced by prescribed SST. Tropical response

    Energy Technology Data Exchange (ETDEWEB)

    Moron, V. [Universite' de Provence, UFR des sciences geographiques et de l' amenagement, Aix-en-Provence (France); Navarra, A. [Istituto Nazionale di Geofisica e Vulcanologia, Bologna (Italy); Ward, M. N. [University of Oklahoma, Cooperative Institute for Mesoscale Meteorological Studies, Norman OK (United States); Foland, C. K. [Hadley Center for Climate Prediction and Research, Meteorological Office, Bracknell (United Kingdom); Friederichs, P. [Meteorologisches Institute des Universitaet Bonn, Bonn (Germany); Maynard, K.; Polcher, J. [Paris Universite' Pierre et Marie Curie, Paris (France). Centre Nationale de la Recherche Scientifique, Laboratoire de Meteorologie Dynamique, Paris

    2001-08-01

    The ECHAM 3.2 (T21), ECHAM (T30) and LMD (version 6, grid-point resolution with 96 longitudes x 72 latitudes) atmospheric general circulation models were integrated through the period 1961 to 1993 forces with the same observed Sea Surface Temperatures (SSTs) as compiled at the Hadley Centre. Three runs were made for each model starting from different initial conditions. The large-scale tropical inter-annual variability is analysed to give a picture of a skill of each model and of some sort of combination of the three models. To analyse the similarity of model response averaged over the same key regions, several widely-used indices are calculated: Southern Oscillation Index (SOI), large-scale wind shear indices of the boreal summer monsoon in Asia and West Africa and rainfall indices for NE Brazil, Sahel and India. Even for the indices where internal noise is large, some years are consistent amongst all the runs, suggesting inter-annual variability of the strength of SST forcing. Averaging the ensemble mean of the three models (the super-ensemble mean) yields improved skill. When each run is weighted according to its skill, taking three runs from different models instead of three runs of the same model improves the mean skill. There is also some indication that one run of a given model could be better than another, suggesting that persistent anomalies could change its sensitivity to SST. The index approach lacks flexibility to assess whether a model's response to SST has been geographically displaced. It can focus on the first mode in the global tropics, found through singular value decomposition analysis, which is clearly related to El Nino/Southern Oscillation (ENSO) in all seasons. The Observed-Model and Model-Model analyses lead to almost the same patterns, suggesting that the dominant pattern of model response is also the most skilful mode. Seasonal modulation of both skill and spatial patterns (both model and observed) clearly exists with highest skill

  12. Second-harmonic plasma response in diffusion-controlled surface-wave-sustained discharges

    Science.gov (United States)

    Stoev, L.

    2008-05-01

    The formation of nonlinear plasma response at the second harmonic frequency in diffusion controlled surface-wave-sustained discharges is studied theoretically. The study is aimed at estimating theoretically the ratio of the squared amplitudes of the wave field of fundamental frequency and of the resulting - from the nonlinear effects - electric field at the second harmonic frequency. The model presented is intended for further use in discharge diagnostics.

  13. Shock Wave Speed and Transient Response of PE Pipe with Steel-Mesh Reinforcement

    Directory of Open Access Journals (Sweden)

    Wuyi Wan

    2016-01-01

    Full Text Available A steel mesh can improve the tensile strength and stability of a polyethylene (PE pipe in a water supply pipeline system. However, it can also cause more severe water hammer hazard due to increasing wave speed. In order to analyze the influence of the steel mesh on the shock wave speed and transient response processes, an improved wave speed formula is proposed by incorporating the equivalent elastic modulus. A field measurement validates the wave speed formula. Moreover, the transient wave propagation and extreme pressures are simulated and compared by the method of characteristics (MOC for reinforced PE pipes with various steel-mesh densities. Results show that a steel mesh can significantly increase the shock wave speed in a PE pipe and thus can cause severe peak pressure and hydraulic surges in a water supply pipeline system. The proposed wave speed formula can more reasonably evaluate the wave speed and improve the transient simulation of steel-mesh-reinforced PE pipes.

  14. A multichannel frequency response analyser for impedance spectroscopy on power sources

    Directory of Open Access Journals (Sweden)

    DANIEL J. L. BRETT

    2013-06-01

    Full Text Available A low-cost multi-channel frequency response analyser (FRA has been developed based on a DAQ (data acquisition/LabVIEW interface. The system has been tested for electric and electrochemical impedance measurements. This novel association of hardware and software demonstrated performance comparable to a commercial potentiostat / FRA for passive electric circuits. The software has multichannel capabilities with minimal phase shift for 5 channels when operated below 3 kHz. When applied in active (galvanostatic mode in conjunction with a commercial electronic load (by discharging a lead acid battery at 1.5 A the performance was fit for purpose, providing electrochemical information to characterize the performance of the power source.

  15. Effect of follicular wave synchronization on superovulatory response of Girolando embryo donors

    Directory of Open Access Journals (Sweden)

    Joaquim Esquerdo Ferreira

    2014-11-01

    Full Text Available The objective of this study was to evaluate the effect of the follicular wave synchronization method on the superovulatory response of Girolando embryo donors. Seven cows and five heifers were divided into three treatments according to the method of the follicular wave synchronization prior to superovulation. The donors were superovulated with eight FSH decreasing doses, adding 133 mg per animal. The superovulatory response was evaluated using an ultrasound device to quantify the number of corpora lutea. The number and quality of recovered structures were also evaluated. Animal category (cow or heifer and genetic group influenced the superovulatory response, in which heifers showed a greater response (100% in all treatments compared with cows, which showed 85.7%, 57.1% and 57.1% superovulatory response for standing estrus, GnRH and P4 + BE groups, respectively. The genetic group also showed influence on superovulatory response, in which the 3/8 animals had an average of 10.3 corpora lutea per donor compared with the 3/4 animals, which showed 4.9. The follicular wave synchronization treatments did not show differences in superovulatory response, recovered structures and viable structures. The treatment of follicular wave synchronization with GnRH or with P4 + BE can be used in Girolando donors with the same efficiency as the standing estrus group, and 3/8 Girolando heifers respond better to the superovulatory treatment.

  16. Transcriptome analyses of Bactericera cockerelli adults in response to "Candidatus Liberibacter solanacearum" infection.

    Science.gov (United States)

    Nachappa, Punya; Levy, Julien; Tamborindeguy, Cecilia

    2012-10-01

    The potato/tomato psyllid, Bactericera cockerelli (Šulc) is an economically important crop pest that not only causes damage through its feeding but also transmits the bacterium, "Candidatus Liberibacter solanacearum" (CLs), which causes zebra chip disease in potato. There is some information about the phenotypic effects of phytopathogenic bacteria on their insect vectors; however, there are no published reports of the molecular mechanisms underlying phytopathogenic bacteria-insect vector interaction. In order to investigate the effects of CLs infection on B. cockerelli, transcriptomic analyses of CLs-infected and uninfected adult psyllids that were reared on potato were performed. De novo assembly of cDNA sequences generated 136,518 and 109,983 contigs for infected and uninfected insect libraries with an average contig length of 514 bp. BlastX analysis against the NCBI-nr database revealed that 33.33 % had significant matches. Gene ontology data illustrated that the majority of the expressed psyllid genes are involved in metabolic process, biological regulation, binding and catalytic activity. The psyllid transcriptome had an abundance of genes such as vitellogenin, heat shock protein, ejaculatory bulb-specific protein, ferritin, and cytochrome oxidase. Notably absent in the psyllid transcriptome were innate immunity genes induced in response to Gram-negative bacteria (IMD pathway). Several functionally diverse contigs related to symbiotic bacteria including the primary endosymbiont Carsonella ruddii, Wolbachia, and CLs in the psyllid transcriptome were identified. A total of 247 contigs showed differential expression in response to CLs infection including immune and stress-related genes and vitellogenins. Expression analyses of selected psyllid genes were performed on psyllids that were exclusively reared on potato (host of the insects used for RNAseq) and psyllids exclusively reared on tomato (alternative host of psyllids). These genes showed similar expression

  17. Exposure-Response Analyses for Tafenoquine after Administration to Patients with Plasmodium vivax Malaria.

    Science.gov (United States)

    Tenero, David; Green, Justin A; Goyal, Navin

    2015-10-01

    Tafenoquine (TQ), a new 8-aminoquinoline with activity against all stages of the Plasmodium vivax life cycle, is being developed for the radical cure of acute P. vivax malaria in combination with chloroquine. The efficacy and exposure data from a pivotal phase 2b dose-ranging study were used to conduct exposure-response analyses for TQ after administration to subjects with P. vivax malaria. TQ exposure (i.e., area under the concentration-time curve [AUC]) and region (Thailand compared to Peru and Brazil) were found to be statistically significant predictors of clinical response based on multivariate logistic regression analyses. After accounting for region/country, the odds of being relapse free at 6 months increased by approximately 51% (95% confidence intervals [CI], 25%, 82%) for each 25-U increase in AUC above the median value of 54.5 μg · h/ml. TQ exposure was also a significant predictor of the time to relapse of the infection. The final parametric, time-to-event model for the time to relapse, included a Weibull distribution hazard function, AUC, and country as covariates. Based on the model, the risk of relapse decreased by 30% (95% CI, 17% to 42%) for every 25-U increase in AUC. Monte Carlo simulations indicated that the 300-mg dose of TQ would provide an AUC greater than the clinically relevant breakpoint obtained in a classification and regression tree (CART) analysis (56.4 μg · h/ml) in more than 90% of subjects and consequently result in a high probability of being relapse free at 6 months. This model-based approach was critical in selecting an appropriate phase 3 dose. (This study has been registered at ClinicalTrials.gov under registration no. NCT01376167.).

  18. NONLINEAR DYNAMICS RESPONSE OF CASING PIPE UNDER COMBINED WAVE-CURRENT

    Institute of Scientific and Technical Information of China (English)

    TANG You-gang; GU Jia-yang; ZUO Jian-li; MIN Jian-qin

    2005-01-01

    The vortex-induced nonlinear vibration of casing pipes in the deep water was studied considering the loads of current and combined wave-current. The vortex-induced vibration equation of a casing pipe was set up considering the beam mode and Morison's nonlinear fluid loads as well as the vortex-excited loads. The approach of calculating vortex-excited nonlinear vibration by Galerkin's method was proposed. The natural vibration frequencies and modes were obtained, and the response including primary resonance induced by current and the composite resonance under combined wave-current for the 170 m long casing pipe in the 160 m depth of water were investigated. The results show that the dynamics response of casing pipe obviously increases, and the complicated response behaviors of casing pipe are described under combined wave-current.

  19. A hybrid method based upon nonlinear Lamb wave response for locating a delamination in composite laminates.

    Science.gov (United States)

    Yelve, Nitesh P; Mitra, Mira; Mujumdar, P M; Ramadas, C

    2016-08-01

    A new hybrid method based upon nonlinear Lamb wave response in time and frequency domains is introduced to locate a delamination in composite laminates. In Lamb wave based nonlinear method, the presence of damage is shown by the appearance of higher harmonics in the Lamb wave response. The proposed method not only uses this spectral information but also the corresponding temporal response data, for locating the delamination. Thus, the method is termed as a hybrid method. The paper includes formulation of the method and its application to locate a Barely Visible Impact Damage (BVID) induced delamination in a Carbon Fiber Reinforced Polymer (CFRP) laminate. The method gives the damage location fairly well. It is a baseline free method, as it does not need data from the pristine specimen.

  20. Seismic velocity changes of P and S waves associated with the 2011 Tohoku-Oki earthquake (Mw 9.0) as inferred from analyses of repeating earthquakes

    Science.gov (United States)

    Pacheco, Karim; Nishimura, Takeshi; Nakahara, Hisashi

    2017-04-01

    P and S waves radiating from repeating earthquakes are analysed to identify subtle changes in seismic wave velocity associated with the Mw 9.0 Tohoku-Oki earthquake at shallow and deep zones in NE Japan. Accurate measurement of the changes in traveltimes of P and S waves needs high precision of the repeating earthquake's hypocentre parameters, but a large area of NE Japan was damaged so that usual hypocentre relocation methods may not be applicable. Therefore, we develop a new inversion method to simultaneously determine velocity changes of the structure as well as hypocentre parameters of repeating earthquakes. We represent arrival time differences of body waves from a pair of repeating earthquakes occurring before and after a target large earthquake by linear equations of relative locations, origin times and station correction factors, and determine these parameters by using a least-squares method. Arrival time differences at stations for a set of 25 repeating earthquakes are measured by comparing the observed waveforms. Applying the inversion method to these data, we find that traveltime delays up to about 0.04 s for the S wave are widely distributed in NE Japan close to the large slip area of the Tohoku-Oki earthquake. Traveltime delays for P waves are much smaller than those for S waves. The spatial change of traveltime delays are not well correlated with those of strong motions. This implies that the traveltime delays are not caused only in the shallow subsurface. To investigate where the seismic velocity changes occur, we separately analyse the repeating earthquakes occurring in the north and south regions of NE Japan, and observe a spatial shift of large station correction factors for the S wave: large station correction factors estimated from the repeating earthquakes located in the north are shifted to the south area of NE Japan, while those from the repeating earthquakes of the south are shifted to the north area. From comparisons of these spatial

  1. Taking a comparative approach: analysing personality as a multivariate behavioural response across species.

    Directory of Open Access Journals (Sweden)

    Alecia J Carter

    Full Text Available Animal personality, repeatable behaviour through time and across contexts, is ecologically and evolutionarily important as it can account for the exhibition of sub-optimal behaviours. Interspecific comparisons have been suggested as important for understanding the evolution of animal personality; however, these are seldom accomplished due, in part, to the lack of statistical tools for quantifying differences and similarities in behaviour between groups of individuals. We used nine species of closely-related coral reef fishes to investigate the usefulness of ecological community analyses for the analysis of between-species behavioural differences and behavioural heterogeneity. We first documented behavioural carryover across species by observing the fishes' behaviour and measuring their response to a threatening stimulus to quantify boldness. Bold fish spent more time away from the reef and fed more than shy fish. We then used ecological community analysis tools (canonical variate analysis, multi-response permutation procedure, and permutational analysis of multivariate dispersion and identified four 'clusters' of behaviourally similar fishes, and found that the species differ in the behavioural variation expressed; some species are more behaviourally heterogeneous than others. We found that ecological community analysis tools are easily and fruitfully applied to comparative studies of personality and encourage their use by future studies.

  2. Free vibration, wave propagation and tension analyses of a sandwich micro/nano rod subjected to electric potential using strain gradient theory

    Science.gov (United States)

    Arefi, Mohammad; Zenkour, Ashraf M.

    2016-11-01

    Strain gradient theory is used to study free vibration, wave propagation and tension analyses of a sandwich micro/nano rod made of piezoelectric materials under electric potential. The structure is resting on a Pasternak’s foundation medium. Love’s rod model is used for derivation of displacement field. The piezoelectric face sheets are subjected to two-dimensional electric potential including an applied voltage at top of plate and a cosine term along the thickness direction. Hamilton’s principle is used to derive governing equations of motion in terms of axial displacement and electric potential. Three distinct behaviors of the present problem including free vibration, wave propagation and tension analyses are performed. Some important numerical results are presented in detail to capture the effect of materials length scales and applied voltage on the different behaviors of microrod.

  3. Waving goodbye to history? A response to Keith Jenkins

    NARCIS (Netherlands)

    Palladino, P

    1999-01-01

    In response to Purvis and Weatherill, Penelope Corfield reiterates her contention that some women's history is broadening fruitfully into gender history. It is ironic that some feminists should express disapproval of the trend and the nomenclature, when modern feminism itself pioneered the identific

  4. Wave-induced Hydroelastic response of fast monohull ships

    DEFF Research Database (Denmark)

    Jensen, Jørgen Juncher

    1996-01-01

    High-speed ships are weight sensitive structures and high strength steel, aluminium or composites are preferred building materials. it is characteristic for these materials that they result in larger hull flexibility than more conventional materials. Therefore, for large fast ships the lowest...... to the hull flexibility due to the high zero crossing periods associated with the extreme responses....

  5. Waving goodbye to history? A response to Keith Jenkins

    NARCIS (Netherlands)

    Palladino, P

    1999-01-01

    In response to Purvis and Weatherill, Penelope Corfield reiterates her contention that some women's history is broadening fruitfully into gender history. It is ironic that some feminists should express disapproval of the trend and the nomenclature, when modern feminism itself pioneered the identific

  6. Global functional analyses of cellular responses to pore-forming toxins.

    Directory of Open Access Journals (Sweden)

    Cheng-Yuan Kao

    2011-03-01

    Full Text Available Here we present the first global functional analysis of cellular responses to pore-forming toxins (PFTs. PFTs are uniquely important bacterial virulence factors, comprising the single largest class of bacterial protein toxins and being important for the pathogenesis in humans of many Gram positive and Gram negative bacteria. Their mode of action is deceptively simple, poking holes in the plasma membrane of cells. The scattered studies to date of PFT-host cell interactions indicate a handful of genes are involved in cellular defenses to PFTs. How many genes are involved in cellular defenses against PFTs and how cellular defenses are coordinated are unknown. To address these questions, we performed the first genome-wide RNA interference (RNAi screen for genes that, when knocked down, result in hypersensitivity to a PFT. This screen identifies 106 genes (∼0.5% of genome in seven functional groups that protect Caenorhabditis elegans from PFT attack. Interactome analyses of these 106 genes suggest that two previously identified mitogen-activated protein kinase (MAPK pathways, one (p38 studied in detail and the other (JNK not, form a core PFT defense network. Additional microarray, real-time PCR, and functional studies reveal that the JNK MAPK pathway, but not the p38 MAPK pathway, is a key central regulator of PFT-induced transcriptional and functional responses. We find C. elegans activator protein 1 (AP-1; c-jun, c-fos is a downstream target of the JNK-mediated PFT protection pathway, protects C. elegans against both small-pore and large-pore PFTs and protects human cells against a large-pore PFT. This in vivo RNAi genomic study of PFT responses proves that cellular commitment to PFT defenses is enormous, demonstrates the JNK MAPK pathway as a key regulator of transcriptionally-induced PFT defenses, and identifies AP-1 as the first cellular component broadly important for defense against large- and small-pore PFTs.

  7. Trend modelling of wave parameters and application in onboard prediction of ship responses

    DEFF Research Database (Denmark)

    Montazeri, Najmeh; Nielsen, Ulrik Dam; Jensen, J. Juncher

    2015-01-01

    This paper presents a trend analysis for prediction of sea state parameters onboard shipsduring voyages. Given those parameters, a JONSWAP model and also the transfer functions, prediction of wave induced ship responses are thus made. The procedure is tested with full-scale data of an in-service ......This paper presents a trend analysis for prediction of sea state parameters onboard shipsduring voyages. Given those parameters, a JONSWAP model and also the transfer functions, prediction of wave induced ship responses are thus made. The procedure is tested with full-scale data of an in...

  8. Response of waves and coastline evolution to climate variability off the Niger Delta coast during the past 110 years

    Science.gov (United States)

    Dada, Olusegun A.; Li, Guangxue; Qiao, Lulu; Ma, Yanyan; Ding, Dong; Xu, Jishang; Li, Pin; Yang, Jichao

    2016-08-01

    River deltas, low-lying landforms that host critical economic infrastructures and diverse ecosystems as well as high concentrations of human population, are highly vulnerable to the effects of global climate change. In order to understand the wave climate, their potential changes and implication on coastline evolution for environment monitoring and sustainable management of the Niger Delta in the Gulf of Guinea, an investigation was carried out based on offshore wave statistics of an 110-year time series (1900-2010) dataset obtained from the ECMWF ERA-20C atmospheric reanalysis. Results of multivariate regression analyses indicate that interannual mean values of Hs and Tm trends tended to increase over time, especially in the western part of the delta coast, so that they are presently (1980 and 2010) up to 264 mm (300%) and 0.32 s (22%), respectively, higher than 80 years (1900-1930) ago. The maximum directions of the wave have become more westerly (southward) than southerly (westward) by up to 2° (33%) and the mean longshore sediment transport rate has increased by more than 8% over the last 80 years. The linear regression analysis for shoreline changes from 1987 to 2013 shows an erosional trend at the western part of the delta and accretional trends towards eastern part. The relationship between wave climate of the study area and atmospheric circulation using Pearson's correlation shows that the Atlantic Multidecadal Oscillation (AMO), North Atlantic Oscillation (NAO), East Atlantic pattern (EA) and El-Nino/Southern Oscillation (ENSO) Index explain significant proportion of the seasonal and annual wave variabilities compared to other indices. But it is most likely that the combination of these climatic indices acting together or separately constitutes a powerful and effective mechanism responsible for much of the variability of the offshore Niger Delta wave climate. The study concludes that changing wave climate off the Niger Delta has strong implications on the

  9. RANS Simulation of the Heave Response of a Two-Body Floating Point Wave Absorber: Preprint

    Energy Technology Data Exchange (ETDEWEB)

    Yu, Y.; Li, Y.

    2011-03-01

    A preliminary study on a two-body floating wave absorbers is presented in this paper. A Reynolds-Averaged Navier-Stokes computational method is applied for analyzing the hydrodynamic heave response of the absorber in operational wave conditions. The two-body floating wave absorber contains a float section and a submerged reaction section. For validation purposes, our model is first assumed to be locked. The two sections are forced to move together with each other. The locked single body model is used in a heave decay test, where the RANS result is validated with the experimental measurement. For the two-body floating point absorber simulation, the two sections are connected through a mass-spring-damper system, which is applied to simulate the power take-off mechanism under design wave conditions. Overall, the details of the flow around the absorber and its nonlinear interaction with waves are investigated, and the power absorption efficiency of the two-body floating wave absorber in waves with a constant value spring-damper system is examined.

  10. Social Responsibility through the Spanish University Radio Waves

    Directory of Open Access Journals (Sweden)

    Regina Pinto Zúñiga

    2017-01-01

    Full Text Available College radio is built with mechanisms through which students can approach to the labor market, but it is also built as a media in which civil society can take an active part. The objective that we plant is to analyze the need to introduce and preserve the concept of social responsibility in the Spanish university radio stations for attaining the integration between the social system and the university. We designed a methodology based on interviews with those responsible for the Spanish college radio stations that broadcast regularly. Somehow, most of the radio stations analyzed have been incorporating this way of working to their daily basis, making the future professionals in the communication field to contemplate as usual and needed the citizens’ cooperation in order to build the radiophonic speeches, which will revert into a more conciliatory future between people and media.

  11. Analytical solution for wave-induced response of isotropic poro-elastic seabed

    Institute of Scientific and Technical Information of China (English)

    2010-01-01

    By use of separation of variables,the governing equations describing the Biot consolidation model is firstly transformed into a complex coefficient linear homogeneous ordinary differential equation,and the general solution of the horizontal displacement of seabed is constructed by employing a complex wave number,thus,all the explicit analytical solutions of the Biot consolidation model are determined. By comparing with the experimental results and analytical solution of Yamamoto etc. and the analytical solution of Hsu and Jeng,the validity and superiority of the suggested solution are verified. After investigating the influence of seabed depth on the wave-induced response of isotropic poro-elastic seabed based on the present theory,it can be concluded that the influence depth of wave-induced hydrodynamic pressure in the seabed is equal to the wave length.

  12. Crustal and upper mantle S-wave velocity structures across the Taiwan Strait from ambient seismic noise and teleseismic Rayleigh wave analyses

    Science.gov (United States)

    Huang, Y.; Yao, H.; Wu, F. T.; Liang, W.; Huang, B.; Lin, C.; Wen, K.

    2013-12-01

    Although orogeny seems to have stopped in western Taiwan large and small earthquakes do occur in the Taiwan Strait. Limited studies have focused on this region before and were barely within reach for comprehensive projects like TAICRUST and TAIGER for logistical reasons; thus, the overall crustal structures of the Taiwan Strait remain unknown. Time domain empirical Green's function (TDEGF) from ambient seismic noise to determine crustal velocity structure allows us to study an area using station pairs on its periphery. This research aims to resolve 1-D average crustal and upper mantle S-wave velocity (Vs) structures alone paths of several broadband station-pairs across the Taiwan Strait; 5-120 s Rayleigh wave phase velocity dispersion data derived by combining TDEGF and traditional surface wave two-station method (TS). The average Vs structures show significant differences in the upper 15 km as expected. In general, the highest Vs are observed in the coastal area of Mainland China and the lowest Vs appear along the southwest offshore of the Taiwan Island; they differ by about 0.6-1.1 km/s. For different parts of the Strait, the Vs are lower in the middle by about 0.1-0.2 km/s relative to those in the northern and southern parts. The overall crustal thickness is approximately 30 km, much thinner and less variable than under the Taiwan Island.

  13. Dynamic Response of Underground Circular Lining Tunnels Subjected to Incident P Waves

    Directory of Open Access Journals (Sweden)

    Hua Xu

    2014-01-01

    Full Text Available Dynamic stress concentration in tunnels and underground structures during earthquakes often leads to serious structural damage. A series solution of wave equation for dynamic response of underground circular lining tunnels subjected to incident plane P waves is presented by Fourier-Bessel series expansion method in this paper. The deformation and stress fields of the whole medium of surrounding rock and tunnel were obtained by solving the equations of seismic wave propagation in an elastic half space. Based on the assumption of a large circular arc, a series of solutions for dynamic stress were deduced by using a wave function expansion approach for a circular lining tunnel in an elastic half space rock medium subjected to incident plane P waves. Then, the dynamic response of the circular lining tunnel was obtained by solving a series of algebraic equations after imposing its boundary conditions for displacement and stress of the circular lining tunnel. The effects of different factors on circular lining rock tunnels, including incident frequency, incident angle, buried depth, rock conditions, and lining stiffness, were derived and several application examples are presented. The results may provide a good reference for studies on the dynamic response and aseismic design of tunnels and underground structures.

  14. Assessing regional and interspecific variation in threshold responses of forest breeding birds through broad scale analyses.

    Directory of Open Access Journals (Sweden)

    Yntze van der Hoek

    Full Text Available BACKGROUND: Identifying persistence and extinction thresholds in species-habitat relationships is a major focal point of ecological research and conservation. However, one major concern regarding the incorporation of threshold analyses in conservation is the lack of knowledge on the generality and transferability of results across species and regions. We present a multi-region, multi-species approach of modeling threshold responses, which we use to investigate whether threshold effects are similar across species and regions. METHODOLOGY/PRINCIPAL FINDINGS: We modeled local persistence and extinction dynamics of 25 forest-associated breeding birds based on detection/non-detection data, which were derived from repeated breeding bird atlases for the state of Vermont. We did not find threshold responses to be particularly well-supported, with 9 species supporting extinction thresholds and 5 supporting persistence thresholds. This contrasts with a previous study based on breeding bird atlas data from adjacent New York State, which showed that most species support persistence and extinction threshold models (15 and 22 of 25 study species respectively. In addition, species that supported a threshold model in both states had associated average threshold estimates of 61.41% (SE = 6.11, persistence and 66.45% (SE = 9.15, extinction in New York, compared to 51.08% (SE = 10.60, persistence and 73.67% (SE = 5.70, extinction in Vermont. Across species, thresholds were found at 19.45-87.96% forest cover for persistence and 50.82-91.02% for extinction dynamics. CONCLUSIONS/SIGNIFICANCE: Through an approach that allows for broad-scale comparisons of threshold responses, we show that species vary in their threshold responses with regard to habitat amount, and that differences between even nearby regions can be pronounced. We present both ecological and methodological factors that may contribute to the different model results, but propose that

  15. Wave

    DEFF Research Database (Denmark)

    Ibsen, Lars Bo

    2008-01-01

    Estimates for the amount of potential wave energy in the world range from 1-10 TW. The World Energy Council estimates that a potential 2TW of energy is available from the world’s oceans, which is the equivalent of twice the world’s electricity production. Whilst the recoverable resource is many t...

  16. Divergence Between Nonlinear and Equivalent-Linear 1D Site Response Analyses for Different V S Realizations of Typical Clay Sites

    Science.gov (United States)

    Eskandarinejad, Alireza; Jahanandish, Mojtaba; Zafarani, Hamid

    2017-06-01

    Surface ground motions can be obtained via various methods of analysis such as equivalent-linear (EL) and nonlinear (NL) one-dimensional numerical simulations. Selection of analysis method would be a challenging issue due to difficulty of input data preparation. The uncertainty inherent in soil parameters and shear wave velocity has significant impact on the soil surface hazard analysis through amplification function. In the present study, realizations of two clay sites in Shiraz city, southern Iran, along with three hypothetical sites are selected to examine the divergence between EL and NL ground response analyses. Two constitutive models, namely modified hyperbolic Kondner-Zelasko (MKZ) and general quadratic/hyperbolic (GQ/H), are implemented in site response analyses of synthetic profiles generated for reference profiles. The GQ/H model requires user-defined shear strength to simulate soil behavior. Two approaches of shear strength estimation are utilized in the current study. Several issues related to site response analysis are investigated such as effect of shear strength estimation method, input ground-motion intensity, and soil condition on the divergence between EL and NL spectral accelerations. The obtained EL/NL spectral response ratios are presented as a function of either shear strain index or oscillator period for the abovementioned issues. Moreover, 20% difference thresholds of the shear strain index are computed and compared with those from previous researches.

  17. Computational study of human head response to primary blast waves of five levels from three directions.

    Directory of Open Access Journals (Sweden)

    Chenzhi Wang

    Full Text Available Human exposure to blast waves without any fragment impacts can still result in primary blast-induced traumatic brain injury (bTBI. To investigate the mechanical response of human brain to primary blast waves and to identify the injury mechanisms of bTBI, a three-dimensional finite element head model consisting of the scalp, skull, cerebrospinal fluid, nasal cavity, and brain was developed from the imaging data set of a human female. The finite element head model was partially validated and was subjected to the blast waves of five blast intensities from the anterior, right lateral, and posterior directions at a stand-off distance of one meter from the detonation center. Simulation results show that the blast wave directly transmits into the head and causes a pressure wave propagating through the brain tissue. Intracranial pressure (ICP is predicted to have the highest magnitude from a posterior blast wave in comparison with a blast wave from any of the other two directions with same blast intensity. The brain model predicts higher positive pressure at the site proximal to blast wave than that at the distal site. The intracranial pressure wave invariably travels into the posterior fossa and vertebral column, causing high pressures in these regions. The severities of cerebral contusions at different cerebral locations are estimated using an ICP based injury criterion. Von Mises stress prevails in the cortex with a much higher magnitude than in the internal parenchyma. According to an axonal injury criterion based on von Mises stress, axonal injury is not predicted to be a cause of primary brain injury from blasts.

  18. Resonant response of a strong electromagnetic wave beam to a gravitational wave in a static magnetic field

    Institute of Scientific and Technical Information of China (English)

    LI; Fangyu

    2001-01-01

    [1]Gerlach, U. H., Cavity quantum-electrodynamical response to a gravitational wave, Phys. Rev. D, 1992, 46: 1 239.[2]Fortini, P., Gualdi, C., Ortolan, A., Interaction of a gravitational wave with electromagnetic currents, Nuovo Cimento B, 1991,106: 395.[3]Cuomo, D., Franceschetti, G., Panariello, G. et al., Proceeding of International Symposium on Experimental Gravitational Physics, Guangzhou, China (ed. Michelson, F. C.), Singapore: World Scientific, 1992, 262.[4]Logi, W. K., Mickelson, A. R., Electrogravitational conversion cross section in static electromagnetic fields, Phys. Rev. D, 1977, 16: 2 915.[5]Long, H. N., Soa, D. V., Tuan, T. A., The conversion of gravitons into photons in a periodic external electromagnetic field, Phys. Lett. A, 1994, 186: 382.[6]Boccaletti, D., Sabbata, V. D., Fortini, P., Conversion of photons into gravitons and vice versa in a static electromagnetic field, Nuovo Cimento B, 1970, 70: 129.[7]Grishchuk, L. P., Sazhin, M. V., Excitation and detection of standing gravitational waves, Sov. Phys. Jetp, 1975, 41: 787.[8]Gratta, G., Kim, K. J., Melissions, A. et al., Workshop on Beam-Beam and Beam-Radiation Interaction: High Intensity and Nonlinear Effects, Los Angeles, USA (ed. Pellegrini, C.), Singapore: World Scientific, 1992, 70.[9]Chen, P., Palazzi, G. D., Kim, K. J. et al., Workshop on Beam-Beam and Beam-Radiation Interaction: High Intensity and Nonlinear Effects, Los Angeles, USA (ed. Pellegrini, C.), Singapore: World Scientific, 1992, 84.[10]Grishchuk, L. P., Sazhin, M. V., Squeezed quantum states of a harmonic oscillator in the problem of gravitational wave detection. Sov. Phys. Jetp, 1983, 53: 1128.[11]Tang, M. X., Li, F. Y., Luo, J., High frequency gravitational wave of a composite toroidal electrodrynamical resonant system, Acta Physical Sinica, 1997, 6: 161.[12]Li, F. Y., Tang, M. X., Coherent resonant of a strong electromagnetic wave beam to a standing gravitational wave

  19. Analyses on the climate change responses over China under SRES B2 scenario using PRECIS

    Institute of Scientific and Technical Information of China (English)

    XU Yinlong; ZHANG Yong; LIN Erda; LIN Wantao; DONG Wenjie; Richard Jones; David Hassell; Simon Wilson

    2006-01-01

    The PRECIS, a regional climate model system developed at the UK Met Office Hadley Centre for Climate Prediction and Research, which is nested in one-way mode within the HadAM3P, a higher-resolution version of the atmospheric component of the Hadley Centre climate model HadCM3, is employed to simulate the baseline (1961-1990) climate for evaluation of model's capacity of simulating present climate and analyze the future climate change responses in the time-slice of 2071-2100 (2080s) under SRES B2 scenario over China relative to baseline average. It is indicated from the comparison of the simulated baseline climate with in situ observation that PRECIS can simulate the local distribution characteristics of surface air temperature over China quite well; generally speaking, the simulation for precipitation in the north of China and in winter is better than in the south of China and in summer, respectively; the simulation of precipitation in summer is sensitive to topography, and the simulated precipitation values are lower than observations over southeast coastal areas. It is shown from the analyses on the simulated climate change responses in 2080s under SRES B2 scenario relative to baseline that there would be an obvious surface air temperature increase in the north of China relative to that in the south of China, and especially in Northwest China and Northeast China, the amplitude of summer mean surface air temperature increments could reach 5℃; there would be an overall increase of the simulated precipitation in 2080s under SRES B2 scenario over most areas of China, while there would be significant precipitation decreases in South China in winter; there would be obvious precipitation decreases in Northeast China and North China in summer with high surface air temperature increase. However, it presents an obvious precipitation increase over the middle and lower reaches of the Yangtze River in summer.

  20. Analysing vegetation phenology in response to climate change using enhanced bioclimatic indices in Iraq

    Science.gov (United States)

    Daham, Afrah; Han, Dawei; Jolly, William M.; Rico-Ramirez, Miguel

    2017-04-01

    Exchanges of momentum, heat, carbon dioxide, energy, water and mass between the land's surface and the atmosphere are significantly affected by the phenological state of vegetation. Although, most phenology models have the function in analysing and predicting future trends in response to climate change, a bioclimatic index including precipitation in has not been adequately considered in the existing phenology models. In this study a new variable is added to the common set of variables found in the literature review and it is demonstrated how these variables could be combined into an index to quantify the greenness of vegetation throughout the three different years that have been selected (2001, 2006, and 2010). These four selected variables are: Suboptimal (minimum) temperatures, evaporative demand (vapour pressure deficit), photoperiod (daylength), and precipitation. Threshold limits (a lower threshold and an upper threshold) have been set for individual variables, within which the relative phenological performance of the vegetation is assumed to vary from inactive (0) to unconstrained (1). A combined Growing Season Index (GSI) is derived as the product of the four indices. The mean GSI values over twenty one days for the study area during the study period showed a good correlation with the MODerate-resolution Imaging Spectroradiometer (MODIS) and the derived Normalized Difference Vegetation Index (NDVI). The model has been tested for different locations in Iraq (Sulaymaniyah in the north, Wasit in the centre and Basrah in the south) by comparing the model results for these areas with the addition of the precipitation variable and without. The correlation for this model has been improved significantly after adding precipitation as an index in the GSI model. The modified model appears sufficiently robust to reconstruct historical variation as well as to forecast possible future phenological responses to changing climatic conditions. This study is of important value

  1. Extrapolation of extreme response for different mooring line systems of floating wave energy converters

    DEFF Research Database (Denmark)

    Ambühl, Simon; Sterndorff, Martin; Sørensen, John Dalsgaard

    2014-01-01

    Mooring systems for floating wave energy converters (WECs) are a major cost driver. Failure of mooring systems often occurs due to extreme loads. This paper introduces an extrapolation method for extreme response which accounts for the control system of a WEC that controls the loads onto the stru......Mooring systems for floating wave energy converters (WECs) are a major cost driver. Failure of mooring systems often occurs due to extreme loads. This paper introduces an extrapolation method for extreme response which accounts for the control system of a WEC that controls the loads onto...... the structure and the harvested power of the device as well as the fact that extreme loads may occur during operation and not at extreme wave states when the device is in storm protection mode. The extrapolation method is based on shortterm load time series and applied to a case study where up-scaled surge load...

  2. Kinetic features revealed by top-hat electrostatic analysers: numerical simulations and instrument response results

    Science.gov (United States)

    De Marco, Rossana; Marcucci, Maria Federica; Brienza, Daniele; Bruno, Roberto; Consolini, Giuseppe; Perrone, Denise; Valentini, Franceso; Servidio, Sergio; Stabile, Sara; Pezzi, Oreste; Sorriso-Valvo, Luca; Lavraud, Benoit; De Keyser, Johan; Retinò, Alessandro; Fazakerley, Andrew; Wicks, Robert; Vaivads, Andris; Salatti, Mario; Veltri, Pierliugi

    2017-04-01

    Turbulence Heating ObserveR (THOR) is the first mission devoted to study energization, acceleration and heating of turbulent space plasmas, and designed to perform field and particle measurements at kinetic scales in different near-Earth regions and in the solar wind. Solar Orbiter (SolO), together with Solar Probe Plus, will provide the first comprehensive remote and in situ measurements which are critical to establish the fundamental physical links between the Sun's dynamic atmosphere and the turbulent solar wind. The fundamental process of turbulent dissipation is mediated by physical mechanism that occur at a variety of temporal and spatial scales, and most efficiently at the kinetics scales. Hybrid Vlasov-Maxwell simulations of solar-wind turbulence show that kinetic effects manifest as particle beams, production of temperature anisotropies and ring-like modulations, preferential heating of heavy ions. We use a numerical code able to reproduce the response of a typical electrostatic analyzer of top-hat type starting from velocity distribution functions (VDFs) generated by Hybrid Vlasov-Maxwell (HVM) numerical simulations. Here, we show how optimized particle measurements by top-hat analysers can capture the kinetic features injected by turbulence in the VDFs.

  3. Dynamic response of jetting and cementing bucket platform to wave and current loading

    Institute of Scientific and Technical Information of China (English)

    Wang Hu; Wang Deyu

    2006-01-01

    The jetting and cementing bucket platform (JCBP) is a new type offshore oil-drilling platform. This paper aims to establish an analysis method for calculating the dynamic response of this platform. Based on the theory of elastic half space, the dynamic stiffness and damping of the platform's foundation were obtained and attached to the end of the platform's main jackets as a boundary condition. Then using finite element method (FEM), the dynamic response of the platform due to wave and current loading was calculated. Furthermore, the whole platform's finite element model was established and the dynamic response of the platform was calculated. The numerical results demonstrate that the present method by the usage of elastic half space theory and FEM is simple and it is reliable and efficient to calculate dynamic behavior of the platform in response to wave and current loading.

  4. Non-Linear Wave Loads and Ship responses by a time-domain Strip Theory

    DEFF Research Database (Denmark)

    Xia, Jinzhu; Wang, Zhaohui; Jensen, Jørgen Juncher

    1998-01-01

    A non-linear time-domain strip theory for vertical wave loads and ship responses is presented. The theory is generalized from a rigorous linear time-domain strip theory representaton. The hydrodynamic memory effect due to the free surface is approximated by a higher order differential equation...

  5. System Identification of Mistuned Bladed Disks from Traveling Wave Response Measurements

    Science.gov (United States)

    Feiner, D. M.; Griffin, J. H.; Jones, K. W.; Kenyon, J. A.; Mehmed, O.; Kurkov, A. P.

    2003-01-01

    A new approach to modal analysis is presented. By applying this technique to bladed disk system identification methods, one can determine the mistuning in a rotor based on its response to a traveling wave excitation. This allows system identification to be performed under rotating conditions, and thus expands the applicability of existing mistuning identification techniques from integrally bladed rotors to conventional bladed disks.

  6. Response of YBCO/PCBO/YBCO ramp type Josephson junctions to near MM wave irradiation

    NARCIS (Netherlands)

    Terpstra, D.; Gerritsma, G.J.; Rogalla, H.; Gupta, R.; Hu, Q.Y.

    1994-01-01

    A high Tc Josephson device for high frequency detection applications is being developed, consisting of an YBCO/PBCO/YBCO ramp type junction and a broad band log-periodic antenna. In this contribution we present the response of such a device to (near) mm wave irradiation. Shapiro steps have been obse

  7. Wave Dynamic Analysis of the Seismic Response of a Reinforced Concrete Building

    Science.gov (United States)

    Astroza, Rodrigo; Saragoni, G. Rodolfo

    2008-07-01

    This paper evaluates the response of the seven-story instrumented building, Holiday Inn Hotel, during the 1994 Northridge earthquake through the wave propagation dynamic analysis. The building has been instrumented during other earthquakes, the most important of these was the 1971 San Fernando earthquake, where the building was located only 22 [km] from the epicenter and didn't showing structural damage. From the accelerograms analysis is detected the propagation of Rayleigh and soil waves in the building, where the first has a polarized particle motion on a vertical plane and the second has a coupled particle motion in the horizontal plane. Both waves impose their frequencies to the building response, whose fundamental frequency (1.4 [Hz] according to ambient vibration test) is less than the frequencies of the identified waves. Due to the impact that these observations have in the seismic design of buildings, as a first attempt, a simple method is proposed to estimate the drift produced by the propagation of a Rayleigh wave in buildings.

  8. Intertidal sea stars (Pisaster ochraceus) alter body shape in response to wave action.

    Science.gov (United States)

    Hayne, Kurtis J R; Palmer, A Richard

    2013-05-01

    Sea stars are some of the largest mobile animals able to live in the harsh flow environment of wave-exposed, rocky intertidal shores. In addition, some species, such as the northeastern Pacific Pisaster ochraceus, are ecologically significant predators in a broad range of environments, from sheltered lagoons to the most wave-exposed shorelines. How they function and survive under such an extreme range of wave exposures remains a puzzle. Here we examine the ability of P. ochraceus to alter body form in response to variation in flow conditions. We found that sea stars in wave-exposed sites had narrower arms and were lighter per unit arm length than those from sheltered sites. Body form was tightly correlated with maximum velocity of breaking waves across four sites and also varied over time. In addition, field transplant experiments showed that these differences in shape were due primarily to phenotypic plasticity. Sea stars transplanted from a sheltered site to a more wave-exposed site became lighter per unit arm length, and developed narrower arms, after 3 months. The tight correlation between water flow and morphology suggests that wave force must be a significant selective factor acting on body shape. On exposed shores, narrower arms probably reduce both lift and drag in breaking waves. On protected shores, fatter arms may provide more thermal inertia to resist overheating, or more body volume for gametes. Such plastic changes in body shape represent a unique method by which sea stars adapt to spatial, seasonal and possibly short-term variation in flow conditions.

  9. Conditioning effect of transcranial magnetic stimulation evoking motor-evoked potential on V-wave response.

    Science.gov (United States)

    Grosprêtre, Sidney; Martin, Alain

    2014-12-01

    The aim of this study was to examine the collision responsible for the volitional V-wave evoked by supramaximal electrical stimulation of the motor nerve during voluntary contraction. V-wave was conditioned by transcranial magnetic stimulation (TMS) over the motor cortex at several inter-stimuli intervals (ISI) during weak voluntary plantar flexions (n = 10) and at rest for flexor carpi radialis muscle (FCR; n = 6). Conditioning stimulations were induced by TMS with intensity eliciting maximal motor-evoked potential (MEPmax). ISIs used were ranging from -20 to +20 msec depending on muscles tested. The results showed that, for triceps surae muscles, conditioning TMS increased the V-wave amplitude (~ +250%) and the associated mechanical response (~ +30%) during weak voluntary plantar flexion (10% of the maximal voluntary contraction -MVC) for ISIs ranging from +6 to +18 msec. Similar effect was observed at rest for the FCR with ISI ranging from +6 to +12 msec. When the level of force was increased from 10 to 50% MVC or the conditioning TMS intensity was reduced to elicit responses of 50% of MEPmax, a significant decrease in the conditioned V-wave amplitude was observed for the triceps surae muscles, linearly correlated to the changes in MEP amplitude. The slope of this correlation, as well as the electro-mechanical efficiency, was closed to the identity line, indicating that V-wave impact at muscle level seems to be similar to the impact of cortical stimulation. All these results suggest that change in V-wave amplitude is a great index to reflect changes in cortical neural drive addressed to spinal motoneurons.

  10. Nonlinear ionospheric responses to large-amplitude infrasonic-acoustic waves generated by undersea earthquakes

    Science.gov (United States)

    Zettergren, M. D.; Snively, J. B.; Komjathy, A.; Verkhoglyadova, O. P.

    2017-02-01

    Numerical models of ionospheric coupling with the neutral atmosphere are used to investigate perturbations of plasma density, vertically integrated total electron content (TEC), neutral velocity, and neutral temperature associated with large-amplitude acoustic waves generated by the initial ocean surface displacements from strong undersea earthquakes. A simplified source model for the 2011 Tohoku earthquake is constructed from estimates of initial ocean surface responses to approximate the vertical motions over realistic spatial and temporal scales. Resulting TEC perturbations from modeling case studies appear consistent with observational data, reproducing pronounced TEC depletions which are shown to be a consequence of the impacts of nonlinear, dissipating acoustic waves. Thermospheric acoustic compressional velocities are ˜±250-300 m/s, superposed with downward flows of similar amplitudes, and temperature perturbations are ˜300 K, while the dominant wave periodicity in the thermosphere is ˜3-4 min. Results capture acoustic wave processes including reflection, onset of resonance, and nonlinear steepening and dissipation—ultimately leading to the formation of ionospheric TEC depletions "holes"—that are consistent with reported observations. Three additional simulations illustrate the dependence of atmospheric acoustic wave and subsequent ionospheric responses on the surface displacement amplitude, which is varied from the Tohoku case study by factors of 1/100, 1/10, and 2. Collectively, results suggest that TEC depletions may only accompany very-large amplitude thermospheric acoustic waves necessary to induce a nonlinear response, here with saturated compressional velocities ˜200-250 m/s generated by sea surface displacements exceeding ˜1 m occurring over a 3 min time period.

  11. Evaluation of computer programs used for structural analyses of impact response of spent fuel shipping casks

    Energy Technology Data Exchange (ETDEWEB)

    Lewis, B A; Gwinn, K W

    1984-05-01

    This report presents the results of a study of impact analyses of a generic spent-fuel cask. The study compares the use and results of three different finite element computer codes. Seven different cask-like model analyses are considered. The models encompass both linear and nonlinear geometric and material behavior. On the basis of the analyses results, this report recommends what parameters are useful in the comparison of different structural finite element computer programs. 5 references, 36 figures, 11 tables.

  12. Double-side fabrication process and millimeter wave response of intrinsic Josephson junctions

    Institute of Scientific and Technical Information of China (English)

    WU JingBo; YI DongChao; GU ZhengHao; KANG Lin; XU WeiWei; CHEN Jian; WU PeiHeng

    2009-01-01

    We adopted double-side fabrication process to prepare intrinsic Josephson junctions (IJJs) based on Bi2Sr2CaCu2O8-x(BSCCO) single crystals. Using crystal cleavage and double-side argon ion milling, we have successfully fabricated very uniform IJJs with the thickness of single crystal slice less than 200 nm. Using quasi-optical system, the response of the IJJs to millimeter wave radiation was studied. With applied magnetic field perpendicular to a-b plane, we have observed Shapiro steps under millimeter wave radiation, and the Josephson oscillation of each junction was phase-locking.

  13. Response of internal solitary waves to tropical storm Washi in the northwestern South China Sea

    Directory of Open Access Journals (Sweden)

    Z. H. Xu

    2011-11-01

    Full Text Available Based on in-situ time series data from an array of temperature sensors and an acoustic Doppler current profiler on the continental shelf of the northwestern South China Sea, a sequence of internal solitary waves (ISWs were observed during the passage of tropical storm Washi in the summer of 2005, which provided a unique opportunity to investigate the ISW response to the tropical cyclone. The passing tropical storm is found to play an important role in affecting the stratification structure of the water column, and consequently leading to significant variability in the propagating features of the ISWs, such as the polarity reversal and amplitude variations of the waves. The response of the ISWs to Washi can be divided into two stages, direct forcing by the strong wind (during the arrival of Washi and remote forcing via the near-inertial internal waves induced by the tropical storm (after the passage of Washi. The field observations as well as a theoretical analysis suggest that the variations of the ISWs closely coincide with the changing stratification structure and shear currents in accompanied by the typhoon wind and near-inertial waves. This study presents the first observations and analysis of the ISW response to the tropical cyclone in the South China Sea.

  14. Estimation of bending wave intensity in beams using the frequency response technique

    Science.gov (United States)

    Linjama, J.; Lahti, T.

    1992-02-01

    The frequency response approach is applied to the measurement of bending wave intensity, with two or four accelerometers being used. Based on the known structural intensity equations, a comprehensive set of frequency domain expressions is derived for power measurements in a beam. A practical procedure is developed for the general four-transducer method, which allows a usual dual channel FFT analyzer to be employed in multi-channel measurements. The procedure uses the sequential frequency response technique, and is applicable if the situation remains stationary during the data acquisition. In addition, expressions are derived for the determination of the force- and moment-related bending wave power components separately. In a laboratory experiment, the power carried by bending waves was measured in a simple beam, and the methods developed were tested and compared. The frequency response approach was shown to work well in detecting the total power. The estimation of the two bending wave power components, both in the near and the far field, was also demonstrated.

  15. Dynamic Response Analysis for Embedded Large-Cylinder Breakwaters Under Wave Excitation

    Institute of Scientific and Technical Information of China (English)

    王元战; 祝振宇; 周枝荣

    2004-01-01

    A numerical model is developed for dynamic analysis of large-cylinder breakwaters embedded in soft soil. In the model, the large cylinder is taken as a rigid body divided into elements and the soft soil is replaced by discrete 3D nonlinear spring-dashpot systems. The numerical model is used to simulate the dynamic response of a large-cylinder breakwater to breaking wave excitation. The effects of the dynamic stress-strain relationship models of the soil, the radius and embedded depth of the cylinder, the nonlinear behaviors of the soil, and the limit strength condition of the soil on the dynamic responses of the large-cylinder structure are investigated with an example given. It is indicated that the above-mentioned factors have significant effects on the dynamic responses of an embedded large cylinder breakwater under breaking wave excitation.

  16. Seismic responses of a hemispherical alluvial valley to SV Waves: a three-dimensional analytical approximation

    Institute of Scientific and Technical Information of China (English)

    Chenggang Zhao; Jun Dong; Fuping Gao; D.-S.Jeng

    2006-01-01

    An analytical solution to the three-dimensional scattering and diffraction of plane SV-waves by a saturated hemispherical alluvial valley in elastic halfspace is obtained by using Fourier-Bessel series expansion technique.The hemispherical alluvial valley with saturated soil deposits is simulated with Biot's dynamic theory for saturated porous media.The following conclusions based on numerical results can be drawn:(1) there are a significant differences in the seismic response simulation between the previous single-phase models and the present two-phase model;(2)the normalized displacements on the free surface of the alluvial valley depend mainly on the incident wave angles,the dimensionless frequency of the incident SV waves and the porosity of sediments;(3)with the increase of the incident angle,the displacement distributions become more complicated,and the displacements on the free surface of the alluvial valley increase as the porosity of sediments increases.

  17. Retrieval of the P wave reflectivity response from autocorrelation of seismic noise: Jakarta Basin, Indonesia

    Science.gov (United States)

    Saygin, Erdinc; Cummins, Phil R.; Lumley, David

    2017-01-01

    We autocorrelate the continuously recorded seismic wavefield across a dense network of seismometers to map the P wave reflectivity response of the Jakarta Basin, Indonesia. The proximity of this mega city to known active faults and the subduction of the Australian plate, especially when the predominance of masonry construction and thick sedimentary basin fill are considered, suggests that it is a hot spot for seismic risk. In order to understand the type of ground motion that earthquakes might cause in the basin, it is essential to obtain reliable information on its seismic velocity structure. The body wave reflections are sensitive to the sharp velocity contrasts, which makes them useful in seismic imaging. Results show autocorrelograms at different seismic stations with reflected-wave travel time variations, which reflect the variation in basement depth across the thick sedimentary basin. We also confirm the validity of the observed autocorrelation waveforms by conducting a 2-D full waveform modeling.

  18. Analysis for the amplitude oscillatory movements of the ship in response to the incidence wave

    Science.gov (United States)

    Chiţu, M. G.; Zăgan, R.; Manea, E.

    2015-11-01

    Event of major accident navigation near offshore drilling rigs remains unacceptably high, known as the complications arising from the problematic of the general motions of the ship sailing under real sea. Dynamic positioning system is an effective instrument used on board of the ships operating in the extraction of oil and gas in the continental shelf of the seas and oceans, being essential that the personnel on board of the vessel can maintain position and operating point or imposed on a route with high precision. By the adoption of a strict safety in terms of handling and positioning of the vessel in the vicinity of the drilling platform, the risk of accidents can be reduced to a minimum. Possibilities in anticipation amplitudes of the oscillatory movements of the ships navigating in real sea, is a challenge for naval architects and OCTOPUS software is a tool used increasingly more in this respect, complementing navigational facilities offered by dynamic positioning systems. This paper presents a study on the amplitudes of the oscillations categories of supply vessels in severe hydro meteorological conditions of navigation. The study provides information on the RAO (Response Amplitude Operator) response operator of the ship, for the amplitude of the roll movements, in some incident wave systems, interpreted using the energy spectrum Jonswap and whose characteristics are known (significant height of the wave, wave period, pulsation of the wave). Ship responses are analyzed according to different positioning of the ship in relation to the wave front (incident angle ranging from 10 to 10 degree from 0 to 180), highlighting the value of the ship roll motion amplitude. For the study, was used, as a tool for modeling and simulation, the features offered by OCTOPUS software that allows the study of the computerized behavior of the ship on the waves, in the real conditions of navigation. Program library was used for both the vessel itself and navigation modeling

  19. Wave spectral response to sudden changes in wind direction in finite-depth waters

    Science.gov (United States)

    Aijaz, Saima; Rogers, W. Erick; Babanin, Alexander V.

    2016-07-01

    The response of a wind-sea spectrum to sudden changes in wind directions of 180° and 90° is investigated. Numerical simulations using the third-generation wave spectral model SWAN have been undertaken at micro timescales of 30 s and fine spatial resolution of less than 10 m. The results have been validated against the wave data collected during the field campaign at Lake George, Australia. The newly implemented 'ST6' physics in the SWAN model has been evaluated using a selection of bottom-friction terms and the two available functions for the nonlinear energy transfer: (1) exact solution of the nonlinear term (XNL), and (2) discrete interactions approximation (DIA) that parameterizes the nonlinear term. Good agreement of the modelled data is demonstrated directly with the field data and through the known experimental growth curves obtained from the extensive Lake George data set. The modelling results show that of the various combinations of models tested, the ST6/XNL model provides the most reliable computations of integral and spectral wave parameters. When the winds and waves are opposing (180° wind turn), the XNL is nearly twice as fast in the aligning the young wind-sea with the new wind direction than the DIA. In this case, the young wind-sea gradually decouples from the old waves and forms a new secondary peak. Unlike the 180° wind turn, there is no decoupling in the 90° wind turn and the entire spectrum rotates smoothly in the new direction. In both cases, the young wind-sea starts developing in the new wind direction within 10 min of the wind turn for the ST6 while the directional response of the default physics lags behind with a response time that is nearly double of ST6. The modelling results highlight the differences in source term balance among the different models in SWAN. During high wind speeds, the default settings provide a larger contribution from the bottom-friction dissipation than the whitecapping. In contrast, the whitecapping

  20. The vibration of a box-type structure. II - Response to a travelling pressure wave.

    Science.gov (United States)

    Popplewell, N.

    1971-01-01

    A finite element method is formulated for determining the transient response of a box-type structure to a traveling, arbitrarily shaped pressure wave. The method is illustrated by considering an example of practical concern - the sonic boom. The acceleration-time histories of a closed box are compared with those obtained experimentally from a simulated boom. Satisfactory agreement is obtained with only four rectangular elements per individual face and a simplified loading of the box.

  1. Experimental and theoretical studies of spectral alteration in ultrasonic waves resulting from nonlinear elastic response in rock

    Energy Technology Data Exchange (ETDEWEB)

    Johnson, P.A.; McCall, K.R.; Meegan, G.D. Jr.

    1993-01-01

    Experiments in rock show a large nonlinear elastic wave response, far greater than that of gases, liquids and most other solids. The large response is attributed to structural defects in rock including microcracks and grain boundaries. In the earth, a large nonlinear response may be responsible for significant spectral alteration at amplitudes and distances currently considered to be well within the linear elastic regime.

  2. Experimental and theoretical studies of spectral alteration in ultrasonic waves resulting from nonlinear elastic response in rock

    Energy Technology Data Exchange (ETDEWEB)

    Johnson, P.A.; McCall, K.R.; Meegan, G.D. Jr.

    1993-06-01

    Experiments in rock show a large nonlinear elastic wave response, far greater than that of gases, liquids and most other solids. The large response is attributed to structural defects in rock including microcracks and grain boundaries. In the earth, a large nonlinear response may be responsible for significant spectral alteration at amplitudes and distances currently considered to be well within the linear elastic regime.

  3. Experimental and theoretical studies of spectral alteration in ultrasonic waves resulting from nonlinear elastic response in rock

    Energy Technology Data Exchange (ETDEWEB)

    Johnson, P.A.; McCall, K.R.; Meegan, G.D. Jr. [Los Alamos National Lab., NM (United States)

    1993-11-01

    Experiments in rock show a large nonlinear elastic wave response, far greater than that of gases, liquids and most other solids. The large response is attributed to structural defects in rock including microcracks and grain boundaries. In the earth, a large nonlinear response may be responsible for significant spectral alteration at amplitudes and distances currently considered to be well within the linear elastic regime.

  4. Evidence that changes in social cognitions predict changes in self-reported driver behavior: Causal analyses of two-wave panel data.

    Science.gov (United States)

    Elliott, Mark A; Thomson, James A; Robertson, Kirsty; Stephenson, Carry; Wicks, John

    2013-01-01

    Previous research on the theory of planned behavior (TPB) is characterized by cross-sectional tests of the model's proposed causal relationships. In the absence of effective experimental techniques for changing the TPB's cognitive antecedents, the present research aimed to provide a stronger non-experimental test of the model, using causal analyses of two-wave panel data. Two studies of driver behavior were conducted in which naturally occurring within-participant changes in TPB constructs were measured over time, and used to predict corresponding within-participant changes in both intentions and behavior. A two-wave panel design was used in both studies. Study 1 had a one-month gap between baseline and follow-up. At both waves, a convenience sample comprising predominantly university students (N=135) completed questionnaire measures of all TPB cognitions and behavior (compliance with speed limits in urban areas). Cross-lagged multiple regressions and bootstrapping procedures for testing multiple mediators supported all of the relationships proposed by the TPB. These findings were extended in study 2 using a large, non-student sample of speed limit offenders (N=1149), a six-month gap between baseline and follow-up, and a larger number of cognitive antecedents. Participants completed postal questionnaires at both waves to measure all cognitions proposed by the two-component TPB, along with moral norm, anticipated regret, self-identity and speeding on urban roads, country roads, and fast dual carriageways or motorways. Changes in instrumental and affective attitude, descriptive norm, self-efficacy, moral norm, anticipated regret and self-identity predicted changes in intention to speed. Changes in intention and self-efficacy predicted behavior-change. Injunctive norm and perceived controllability did not predict intention or behavior-change. Additionally, direct (unhypothesized) relationships with behavior were found for affective attitude, descriptive norm and

  5. Item response theory analysis of the life orientation test-revised: age and gender differential item functioning analyses.

    Science.gov (United States)

    Steca, Patrizia; Monzani, Dario; Greco, Andrea; Chiesi, Francesca; Primi, Caterina

    2015-06-01

    This study is aimed at testing the measurement properties of the Life Orientation Test-Revised (LOT-R) for the assessment of dispositional optimism by employing item response theory (IRT) analyses. The LOT-R was administered to a large sample of 2,862 Italian adults. First, confirmatory factor analyses demonstrated the theoretical conceptualization of the construct measured by the LOT-R as a single bipolar dimension. Subsequently, IRT analyses for polytomous, ordered response category data were applied to investigate the items' properties. The equivalence of the items across gender and age was assessed by analyzing differential item functioning. Discrimination and severity parameters indicated that all items were able to distinguish people with different levels of optimism and adequately covered the spectrum of the latent trait. Additionally, the LOT-R appears to be gender invariant and, with minor exceptions, age invariant. Results provided evidence that the LOT-R is a reliable and valid measure of dispositional optimism.

  6. Atmospheric Layers in Response to the Propagation of Gravity Waves under Nonisothermal, Wind-shear, and Dissipative Conditions

    OpenAIRE

    Ma, John Z. G.

    2016-01-01

    We study the atmospheric structure in response to the propagation of gravity waves under nonisothermal (nonzero vertical temperature gradient), wind-shear (nonzero vertical zonal/meridional wind speed gradients), and dissipative (nonzero molecular viscosity and thermal conduction) conditions. As an alternative to the “complex wave-frequency” model proposed by Vadas and Fritts, we employ the traditional “complex vertical wave-number” approach to solving an eighth-order complex polynomial dispe...

  7. Frequency-dependent response of a pinned charge-density wave

    Science.gov (United States)

    Vinokur, Valerii; Fogler, Michael

    2003-03-01

    Recent theoretical advances in the theory of collective pinning [M. M. Fogler, Phys. Rev. Lett. 88, 186402 (2002)] enable us to go beyond the usual phenomenology in the theory of a finite-frequency response of a pinned charge-density wave (CDW) and to calculate ω and T dependences of the complex dielectric function without additional assumptions. According to our estimates, in typical electrical experiments on CDW, the dominant process is a thermal activation over atypically shallow barriers. It gives rise to a novel T^3/4-dependence of the linear response, in agreement with the experiment. A close analogy with acoustic attenuation in glassy dielectrics is noted.

  8. Performance of a data-driven technique to changes in wave height and its effect on beach response

    Directory of Open Access Journals (Sweden)

    Jose M. Horrillo-Caraballo

    2016-01-01

    Full Text Available In this study the medium-term response of beach profiles was investigated at two sites: a gently sloping sandy beach and a steeper mixed sand and gravel beach. The former is the Duck site in North Carolina, on the east coast of the USA, which is exposed to Atlantic Ocean swells and storm waves, and the latter is the Milford-on-Sea site at Christchurch Bay, on the south coast of England, which is partially sheltered from Atlantic swells but has a directionally bimodal wave exposure. The data sets comprise detailed bathymetric surveys of beach profiles covering a period of more than 25 years for the Duck site and over 18 years for the Milford-on-Sea site. The structure of the data sets and the data-driven methods are described. Canonical correlation analysis (CCA was used to find linkages between the wave characteristics and beach profiles. The sensitivity of the linkages was investigated by deploying a wave height threshold to filter out the smaller waves incrementally. The results of the analysis indicate that, for the gently sloping sandy beach, waves of all heights are important to the morphological response. For the mixed sand and gravel beach, filtering the smaller waves improves the statistical fit and it suggests that low-height waves do not play a primary role in the medium-term morphological response, which is primarily driven by the intermittent larger storm waves.

  9. Understanding inhibitory mechanisms of lumbar spinal manipulation using H-reflex and F-wave responses: a methodological approach.

    Science.gov (United States)

    Dishman, J Donald; Weber, Kenneth A; Corbin, Roger L; Burke, Jeanmarie R

    2012-09-30

    The purpose of this research was to characterize unique neurophysiologic events following a high velocity, low amplitude (HVLA) spinal manipulation (SM) procedure. Descriptive time series analysis techniques of time plots, outlier detection and autocorrelation functions were applied to time series of tibial nerve H-reflexes that were evoked at 10-s intervals from 100 s before the event until 100 s after three distinct events L5-S1 HVLA SM, or a L5-S1 joint pre-loading procedure, or the control condition. Sixty-six subjects were randomly assigned to three procedures, i.e., 22 time series per group. If the detection of outliers and correlograms revealed a pattern of non-randomness that was only time-locked to a single, specific event in the normalized time series, then an experimental effect would be inferred beyond the inherent variability of H-reflex responses. Tibial nerve F-wave responses were included to determine if any new information about central nervous function following a HVLA SM procedure could be ascertained. Time series analyses of H(max)/M(max) ratios, pre-post L5-S1 HVLA SM, substantiated the hypothesis that the specific aspects of the manipulative thrust lead to a greater attenuation of the H(max)/M(max) ratio as compared to the non-specific aspects related to the postural perturbation and joint pre-loading. The attenuation of the H(max)/M(max) ratio following the HVLA SM procedure was reliable and may hold promise as a translational tool to measure the consistency and accuracy of protocol implementation involving SM in clinical trials research. F-wave responses were not sensitive to mechanical perturbations of the lumbar spine.

  10. Algal Cell Response to Pulsed Waved Stimulation and Its Application to Increase Algal Lipid Production

    Science.gov (United States)

    Savchenko, Oleksandra; Xing, Jida; Yang, Xiaoyan; Gu, Quanrong; Shaheen, Mohamed; Huang, Min; Yu, Xiaojian; Burrell, Robert; Patra, Prabir; Chen, Jie

    2017-01-01

    Generating renewable energy while sequestering CO2 using algae has recently attracted significant research attention, mostly directing towards biological methods such as systems biology, genetic engineering and bio-refining for optimizing algae strains. Other approaches focus on chemical screening to adjust culture conditions or culture media. We report for the first time the physiological changes of algal cells in response to a novel form of mechanical stimulation, or a pulsed wave at the frequency of 1.5 MHz and the duty cycle of 20%. We studied how the pulsed wave can further increase algal lipid production on top of existing biological and chemical methods. Two commonly used algal strains, fresh-water Chlorella vulgaris and seawater Tetraselmis chuii, were selected. We have performed the tests in shake flasks and 1 L spinner-flask bioreactors. Conventional Gravimetric measurements show that up to 20% increase for algal lipid could be achieved after 8 days of stimulation. The total electricity cost needed for the stimulations in a one-liter bioreactor is only one-tenth of a US penny. Gas liquid chromatography shows that the fatty acid composition remains unchanged after pulsed-wave stimulation. Scanning electron microscope results also suggest that pulsed wave stimulation induces shear stress and thus increases algal lipid production. PMID:28186124

  11. Algal Cell Response to Pulsed Waved Stimulation and Its Application to Increase Algal Lipid Production

    Science.gov (United States)

    Savchenko, Oleksandra; Xing, Jida; Yang, Xiaoyan; Gu, Quanrong; Shaheen, Mohamed; Huang, Min; Yu, Xiaojian; Burrell, Robert; Patra, Prabir; Chen, Jie

    2017-02-01

    Generating renewable energy while sequestering CO2 using algae has recently attracted significant research attention, mostly directing towards biological methods such as systems biology, genetic engineering and bio-refining for optimizing algae strains. Other approaches focus on chemical screening to adjust culture conditions or culture media. We report for the first time the physiological changes of algal cells in response to a novel form of mechanical stimulation, or a pulsed wave at the frequency of 1.5 MHz and the duty cycle of 20%. We studied how the pulsed wave can further increase algal lipid production on top of existing biological and chemical methods. Two commonly used algal strains, fresh-water Chlorella vulgaris and seawater Tetraselmis chuii, were selected. We have performed the tests in shake flasks and 1 L spinner-flask bioreactors. Conventional Gravimetric measurements show that up to 20% increase for algal lipid could be achieved after 8 days of stimulation. The total electricity cost needed for the stimulations in a one-liter bioreactor is only one-tenth of a US penny. Gas liquid chromatography shows that the fatty acid composition remains unchanged after pulsed-wave stimulation. Scanning electron microscope results also suggest that pulsed wave stimulation induces shear stress and thus increases algal lipid production.

  12. Proteomic analyses of the response of cyanobacteria to different stress conditions.

    Science.gov (United States)

    Castielli, Ornella; De la Cerda, Berta; Navarro, José A; Hervás, Manuel; De la Rosa, Miguel A

    2009-06-01

    Cyanobacteria are significant contributors to global photosynthetic productivity, thus making it relevant to study how the different environmental stresses can alter their physiological activities. Here, we review the current research work on the response of cyanobacteria to different kinds of stress, mainly focusing on their response to metal stress as studied by using the modern proteomic tools. We also report a proteomic analysis of plastocyanin and cytochrome c(6) deletion mutants of the cyanobacterium Synechocystis sp. PCC 6803 grown under copper or iron deprivation, as compared to wild-type cells, so as to get a further understanding of the metal homeostasis in cyanobacteria and their response to changing environmental conditions.

  13. Enhanced photoacoustic gas analyser response time and impact on accuracy at fast ventilation rates during multiple breath washout.

    Directory of Open Access Journals (Sweden)

    Alex Horsley

    Full Text Available BACKGROUND: The Innocor device contains a highly sensitive photoacoustic gas analyser that has been used to perform multiple breath washout (MBW measurements using very low concentrations of the tracer gas SF6. Use in smaller subjects has been restricted by the requirement for a gas analyser response time of <100 ms, in order to ensure accurate estimation of lung volumes at rapid ventilation rates. METHODS: A series of previously reported and novel enhancements were made to the gas analyser to produce a clinically practical system with a reduced response time. An enhanced lung model system, capable of delivering highly accurate ventilation rates and volumes, was used to assess in vitro accuracy of functional residual capacity (FRC volume calculation and the effects of flow and gas signal alignment on this. RESULTS: 10-90% rise time was reduced from 154 to 88 ms. In an adult/child lung model, accuracy of volume calculation was -0.9 to 2.9% for all measurements, including those with ventilation rate of 30/min and FRC of 0.5 L; for the un-enhanced system, accuracy deteriorated at higher ventilation rates and smaller FRC. In a separate smaller lung model (ventilation rate 60/min, FRC 250 ml, tidal volume 100 ml, mean accuracy of FRC measurement for the enhanced system was minus 0.95% (range -3.8 to 2.0%. Error sensitivity to flow and gas signal alignment was increased by ventilation rate, smaller FRC and slower analyser response time. CONCLUSION: The Innocor analyser can be enhanced to reliably generate highly accurate FRC measurements down at volumes as low as those simulating infant lung settings. Signal alignment is a critical factor. With these enhancements, the Innocor analyser exceeds key technical component recommendations for MBW apparatus.

  14. The phase response and state space of slow wave contractions in the small intestine.

    Science.gov (United States)

    Parsons, Sean P; Huizinga, Jan D

    2017-09-01

    What is the central question of this study? What are the dynamical rules governing interstitial cell of Cajal (ICC)-generated slow wave contractions in the small intestine, as reflected in their phase response curve and state space? What is the main finding and its importance? The phase response curve has a region of phase advance surrounding a phase delay peak. This pattern is important in generating a stable synchrony within the ICC network and is related to the state space of the ICC; in particular, the phase delay peak corresponds to the unstable equilibrium point that threads the ICC's limit cycle. Interstitial cells of Cajal (ICCs) generate electrical oscillations in the gut. Synchronization of the ICC population is required for generation of coherent electrical waves ('slow waves') that cause muscular contraction and thereby move gut content. The phase response curve (PRC) is an experimental measure of the dynamical rules governing a population of oscillators that determine their synchrony and gives an experimental window onto the state space of the oscillator, its dynamical landscape. We measured the PRC of slow wave contractions in the mouse small intestine by the novel combination of diameter mapping and single pulse electrical field stimulation. Phase change (τ) was measured as a function of old phase (ϕ) and distance from the stimulation electrode (d). Plots of τ(ϕ, d) showed an arrowhead-shaped region of phase advance enclosing at its base a phase delay peak. The phase change mirrored the perturbed pattern of contraction waves in response to a pulse. The (ϕ, d) plane is the surface of a displacement tube extending from the limit cycle through state space. To visualize the state space vector field on this tube, latent phase (ϕlat ) was calculated from τ. At the transition from advance to delay, isochrons made boomerang turns before tightening and winding around the phase delay peak corresponding to the unstable equilibrium point that threads the

  15. Selection of the optimum combination of responses for Wave Buoy Analogy - An approach based on local sensitivity analysis

    DEFF Research Database (Denmark)

    Montazeri, Najmeh; Nielsen, Ulrik Dam; Jensen, Jørgen Juncher

    2016-01-01

    One method to estimate the wave spectrum onboard ships is to use measured ship responses. In this method, known also as Wave Buoy Analogy, amongst various responses that are available from sensor measurements, a couple of responses (at least three) are usually utilized. Selec-tion of the best...... combination of ship responses is important. Optimally, this selection should not be implemented manually in onboard applications. Therefore, availability of an automatic response selection procedure would be a great advantage for decision support. In this paper, a local sensitivity analysis is applied...

  16. Prediction of Vertical-Plane Wave Loading and Ship Responses in High Seas

    DEFF Research Database (Denmark)

    Wang, Zhaohui; Xia, Jinzhu; Jensen, Jørgen Juncher

    2000-01-01

    The non-linearities in wave- and slamming-induced rigid-body motions and structural responses of ships such as heave, pitch and vertical bending moments are consistently investigated based on a rational time-domain strip method. A hydrodynamic model for predicting sectional green water force.......From the rather extensive computations and comparisons, it is found that non-linear effects are significant in head and bow waes in the motion-wave resonant region for both heave and pitch motions, bow accelerations and vertical bending moments for two container ships considered, whereas not significant...... for a VLCC. The non-linearities in motions and structural loads of conventional monohull ships seem well predicted by the present non-linear strip theory....

  17. Latent Variable Modelling and Item Response Theory Analyses in Marketing Research

    Directory of Open Access Journals (Sweden)

    Brzezińska Justyna

    2016-12-01

    Full Text Available Item Response Theory (IRT is a modern statistical method using latent variables designed to model the interaction between a subject’s ability and the item level stimuli (difficulty, guessing. Item responses are treated as the outcome (dependent variables, and the examinee’s ability and the items’ characteristics are the latent predictor (independent variables. IRT models the relationship between a respondent’s trait (ability, attitude and the pattern of item responses. Thus, the estimation of individual latent traits can differ even for two individuals with the same total scores. IRT scores can yield additional benefits and this will be discussed in detail. In this paper theory and application with R software with the use of packages designed for modelling IRT will be presented.

  18. A Comparison of Nature Waves and Model Waves with Special Reference to Wave Grouping

    DEFF Research Database (Denmark)

    Burcharth, Hans F.

    This paper represents a comparative analyses of the occurrence of wave grouping in field storm waves and laboratory waves with similar power spectra and wave height distribution.......This paper represents a comparative analyses of the occurrence of wave grouping in field storm waves and laboratory waves with similar power spectra and wave height distribution....

  19. Fully Coupled Three-Dimensional Dynamic Response of a Tension-Leg Platform Floating Wind Turbine in Waves and Wind

    DEFF Research Database (Denmark)

    Kumari Ramachandran, Gireesh Kumar Vasanta; Bredmose, Henrik; Sørensen, Jens Nørkær;

    2014-01-01

    , which is a consequence of the wave-induced rotor dynamics. Loads and coupled responses are predicted for a set of load cases with different wave headings. Further, an advanced aero-elastic code, Flex5, is extended for the TLP wind turbine configuration and the response comparison with the simpler model...... shows a generally good agreement, except for the yaw motion. This deviation is found to be a result of the missing lateral tower flexibility in the simpler model....

  20. Response of a chemical wave to local pulse irradiation in the ruthenium-catalyzed Belousov-Zhabotinsky reaction.

    Science.gov (United States)

    Nakata, Satoshi; Suzuki, Shogo; Ezaki, Takato; Kitahata, Hiroyuki; Nishi, Kei; Nishiura, Yasumasa

    2015-04-14

    The photo-sensitive Belousov-Zhabotinsky (BZ) reaction system was investigated to understand the response of wave propagation to local pulse stimulation in an excitable field. When the chemical wave was irradiated with a bright pulse or a dark pulse, the speed of wave propagation decreased or increased. The timing of pulse irradiation that significantly affected the speed of chemical wave propagation was different with the bright and dark pulses. That is, there is a sensitive point in the chemical wave. The experimental results were qualitatively reproduced by a numerical calculation based on a three-variable Oregonator model that was modified for the photosensitive BZ reaction. These results suggest that the chemical wave is sensitive to the timing of pulse irradiation due to the rates of production of an activator and an inhibitor in the photochemical reaction.

  1. Dignity and cost-effectiveness: analysing the responsibility for decisions in medical ethics.

    Science.gov (United States)

    Robertson, G S

    1984-01-01

    In the operation of a health care system, defining the limits of medical care is the joint responsibility of many parties including clinicians, patients, philosophers and politicians. It is suggested that changes in the potential for prolonging life make it necessary to give doctors guidance which may have to incorporate certain features of utilitarianism, individualism and patient-autonomy. PMID:6502644

  2. Methods for transcriptomic analyses of the porcine host immune response: application to Salmonella infection using microarrays

    Science.gov (United States)

    Technological developments in both the collection and analysis of molecular genetic data over the past few years have provided new opportunities for an improved understanding of the global response to pathogen exposure. Such developments are particularly dramatic for scientists studying the pig, whe...

  3. Tropical cyclones in two atmospheric (re)analyses and their response in two oceanic reanalyses

    Digital Repository Service at National Institute of Oceanography (India)

    Jourdain, N.C.; Barnier, B.; Ferry, N.; Vialard, J.; Menkes, C.E.; Lengaigne, M.; Parent

    Matthieu Lengaigne , Laurent Parent aTropical cyclones in two atmospheric (re in two oceanic reanalyses Nicolas C. Jourdain a,b,⇑, Bernard Barnier b, Nicolas Fe c,f d journal homepage: www.nalyses and their response d, Jérome Vialard c, Christophe E. Menkes c...

  4. Transcriptome Analyses Reveal Candidate Genes Potentially Involved in Al Stress Response in Alfalfa

    Science.gov (United States)

    Liu, Wenxian; Xiong, Conghui; Yan, Longfeng; Zhang, Zhengshe; Ma, Lichao; Wang, Yanrong; Liu, Yajie; Liu, Zhipeng

    2017-01-01

    Alfalfa is the most extensively cultivated forage legume, yet most alfalfa cultivars are not aluminum tolerant, and the molecular mechanisms underlying alfalfa responses to Al stress are largely unknown. In this study, we aimed to understand how alfalfa responds to Al stress by identifying and analyzing Al-stress-responsive genes in alfalfa roots at the whole-genome scale. The transcriptome changes in alfalfa roots under Al stress for 4, 8, or 24 h were analyzed using Illumina high-throughput sequencing platforms. A total of 2464 differentially expressed genes (DEGs) were identified, and most were up-regulated at early (4 h) and/or late (24 h) Al exposure time points rather than at the middle exposure time point (8 h). Metabolic pathway enrichment analysis demonstrated that the DEGs involved in ribosome, protein biosynthesis, and process, the citrate cycle, membrane transport, and hormonal regulation were preferentially enriched and regulated. Biosynthesis inhibition and signal transduction downstream of auxin- and ethylene-mediated signals occur during alfalfa responses to root growth inhibition. The internal Al detoxification mechanisms play important roles in alfalfa roots under Al stress. These findings provide valuable information for identifying and characterizing important components in the Al signaling network in alfalfa and enhance understanding of the molecular mechanisms underlying alfalfa responses to Al stress. PMID:28217130

  5. Statistical properties of coastal long waves analysed through sea-level time-gradient functions: exemplary analysis of the Siracusa, Italy, tide-gauge data

    Science.gov (United States)

    Bressan, L.; Tinti, S.

    2016-01-01

    This study presents a new method to analyse the properties of the sea-level signal recorded by coastal tide gauges in the long wave range that is in a window between wind/storm waves and tides and is typical of several phenomena like local seiches, coastal shelf resonances and tsunamis. The method consists of computing four specific functions based on the time gradient (slope) of the recorded sea level oscillations, namely the instantaneous slope (IS) as well as three more functions based on IS, namely the reconstructed sea level (RSL), the background slope (BS) and the control function (CF). These functions are examined through a traditional spectral fast Fourier transform (FFT) analysis and also through a statistical analysis, showing that they can be characterised by probability distribution functions PDFs such as the Student's t distribution (IS and RSL) and the beta distribution (CF). As an example, the method has been applied to data from the tide-gauge station of Siracusa, Italy.

  6. Analyses of Bifurcations and Stability in a Predator-prey System with Holling Type-IV Functional Response

    Institute of Scientific and Technical Information of China (English)

    Ji-cai Huang; Dong-mei Xiao

    2004-01-01

    In this paper the dynamical behaviors of a predator-prey system with Holling Type-IV functional response are investigated in detail by using the analyses of qualitative method,bifurcation theory,and numerical simulation.The qualitative analyses and numerical simulation for the model indicate that it has a unique stable limit cycle.The bifurcation analyses of the system exhibit static and dynamical bifurcations including saddlenode bifurcation,Hopf bifurcation,homoclinic bifurcation and bifurcation of cusp-type with codimension two(ie,the Bogdanov-Takens bifurcation),and we show the existence of codimension three degenerated equilibrium and the existence of homoclinic orbit by using numerical simulation.

  7. Design and analyses of an ultra-thin flat lens for wave front shaping in the visible

    Energy Technology Data Exchange (ETDEWEB)

    Huang, Kai, E-mail: nianhua110@hotmail.com [Department of Biomedical Engineering, Bioengineering College of Chongqing University, Chongqing University, Chongqing 400044 (China); Li, Yiyan, E-mail: liy10@unlv.nevada.edu [Department of Electrical and Computer Engineering, University of Nevada, Las Vegas, Las Vegas, NV 89154-4026 (United States); Tian, Xuelong, E-mail: xltian@cqu.edu.cn [Department of Biomedical Engineering, Bioengineering College of Chongqing University, Chongqing University, Chongqing 400044 (China); Zeng, Dajun, E-mail: dajunzeng@163.com [Department of Biomedical Engineering, Bioengineering College of Chongqing University, Chongqing University, Chongqing 400044 (China); Gao, Xueli, E-mail: 2455031293@qq.com [Department of Biomedical Engineering, Bioengineering College of Chongqing University, Chongqing University, Chongqing 400044 (China)

    2015-12-04

    An ultra-thin flat lens is proposed for focusing circularly polarized light in the visible range. Anisotropic C-shaped nanoantennas with phase discontinuities are used to form the metasurface of the lens. The phase response of the C-shaped nanoantennas can be manipulated by simply rotating the angle of the unit nanoantenna. A 600 nm incident circularly polarized light is focused by the proposed techniques. Good agreements are observed by using our MoM and a commercial FDTD software package. The computation time spent by using MoM is approximately 10–100 times smaller than using FDTD. All the results show the proposed nanoantenna array has a great potential for nanoscale optical microscopy, solar cell energy conversion enhancement, as well as integrated optical circuits. - Highlights: • Successfully focusing a 600 nm light using a circularly C-shaped nanoantenna array. • The computation time spent by using MoM is approximately 10–100 times smaller than FDTD. • A good agreement is observed using our MoM to the classic FDTD method.

  8. Test method of frequency response based on diamond surface acoustic wave devices

    Institute of Scientific and Technical Information of China (English)

    CHEN Xi-ming; YANG Bao-he; WU Xiao-guo; WU Yi-zhuo

    2011-01-01

    In order to reduce the noises affixed to the signals when testing high frequency devices, a single-port test mode (S11) is used to test frequency response of high frequency (GHz) and dual-port surface acoustic wave devices (SAWDs) in this paper.The feasibility of the test is proved by simulating the Fabry-Perot model. The frequency response of the high-frequency dual-port resonant-type diamond SAWD is measured by S11 and the dual-port test mode (S21), respectively. The results show that the quality factor of the device is 51.29 and the 3 dB bandwidth is 27.8 MHz by S11 -mode measurement, which is better than the S21 mode, and is consistent with the frequency response curve by simulation.

  9. Response of simple quantum systems to different polarizations of gravitational waves in noncommutative phase-space

    CERN Document Server

    Gangopadhyay, Sunandan; Saha, Swarup

    2016-01-01

    Owing to the extreme smallness of any noncommutative scale that may exist in nature, both in the spatial and momentum sector of the quantum phase-space, a credible possibility of their detection lies in the present day gravitational wave detector set-ups, which effectively detects the relative length-scale variations ${\\cal{O}}\\left[10^{-23} \\right]$. With this motivation, we have considered how a free particle and harmonic oscillator in a quantum domain will respond to linearly and circularly polarized gravitational waves if the given phase-space has a noncommutative structure. The results show resonance behaviour in the responses of both free particle and HO systems to GW with both kind of polarizations. We critically analyze all the responses, and their implications in possible detection of noncommutativity. We use the currently available upper-bound estimates on various noncommutative parameters to anticipate the relative size of various response terms. We also argue how the quantum harmonic oscillator sy...

  10. The effect of surface wave propagation on neural responses to vibration in primate glabrous skin.

    Science.gov (United States)

    Manfredi, Louise R; Baker, Andrew T; Elias, Damian O; Dammann, John F; Zielinski, Mark C; Polashock, Vicky S; Bensmaia, Sliman J

    2012-01-01

    Because tactile perception relies on the response of large populations of receptors distributed across the skin, we seek to characterize how a mechanical deformation of the skin at one location affects the skin at another. To this end, we introduce a novel non-contact method to characterize the surface waves produced in the skin under a variety of stimulation conditions. Specifically, we deliver vibrations to the fingertip using a vibratory actuator and measure, using a laser Doppler vibrometer, the surface waves at different distances from the locus of stimulation. First, we show that a vibration applied to the fingertip travels at least the length of the finger and that the rate at which it decays is dependent on stimulus frequency. Furthermore, the resonant frequency of the skin matches the frequency at which a subpopulation of afferents, namely Pacinian afferents, is most sensitive. We show that this skin resonance can lead to a two-fold increase in the strength of the response of a simulated afferent population. Second, the rate at which vibrations propagate across the skin is dependent on the stimulus frequency and plateaus at 7 m/s. The resulting delay in neural activation across locations does not substantially blur the temporal patterning in simulated populations of afferents for frequencies less than 200 Hz, which has important implications about how vibratory frequency is encoded in the responses of somatosensory neurons. Third, we show that, despite the dependence of decay rate and propagation speed on frequency, the waveform of a complex vibration is well preserved as it travels across the skin. Our results suggest, then, that the propagation of surface waves promotes the encoding of spectrally complex vibrations as the entire neural population is exposed to essentially the same stimulus. We also discuss the implications of our results for biomechanical models of the skin.

  11. Geomagnetic and ionospheric response to the arrival of interplanetary shock wave

    Science.gov (United States)

    Belakhovsky, Vladimir; Pilipenko, Vjacheslav; Kozyreva, Olga; Baddeley, Lisa; Sakharov, Yaroslav; Samsonov, Sergey

    2017-04-01

    The magnetosphere and ionosphere response to the arrival of interplanetary shock wave at 24 January 2012 caused by CME was investigated using complex of spacecraft and ground-based instruments. The SSC produce strong increase of the density, temperature, energetic particles fluxes with energies from 40 keV to >2 MeV inside the magnetosphere as seen from the THEMIS, GOES spacecrafts data. The interplanetary shock wave which produce SSC is a not shock wave in the outer magnetosphere (Mf ≈ 0.4) according the THEMIS spacecraft data. SSC produce the substorm development on the night side during prolonged positive Bz-component of IMF and generation of Pc4-5 pulsations on the morning side. On the evening side SSC cause the increase of the TEC (ΔTEC≈ 8-9%), determined by the GPS receivers in Scandinavia. The response was accompanied by the increase of the electron density at the altitudes 100-200 km as seen from the VHF EISCAT radar in Tromso. So the main contribution to TEC increase has the lower part of the ionosphere. Obviously the TEC response is caused the particle precipitation into the ionosphere. It testified by the strong increase of the aurora intensity at different spectrum lines (400-700 nm) which registered by hyperspectral imager NARUSSCA II of the Polar Geophysical institute in Svalbard. The increase of the CNA in Scandinavia and in Svalbard was also registered during SSC. The SSC produce strong increase of the GIC (geomagnetically induced currents) at electric power lines of the Kola Peninsula and Karelia ( 30 A).

  12. The effect of surface wave propagation on neural responses to vibration in primate glabrous skin.

    Directory of Open Access Journals (Sweden)

    Louise R Manfredi

    Full Text Available Because tactile perception relies on the response of large populations of receptors distributed across the skin, we seek to characterize how a mechanical deformation of the skin at one location affects the skin at another. To this end, we introduce a novel non-contact method to characterize the surface waves produced in the skin under a variety of stimulation conditions. Specifically, we deliver vibrations to the fingertip using a vibratory actuator and measure, using a laser Doppler vibrometer, the surface waves at different distances from the locus of stimulation. First, we show that a vibration applied to the fingertip travels at least the length of the finger and that the rate at which it decays is dependent on stimulus frequency. Furthermore, the resonant frequency of the skin matches the frequency at which a subpopulation of afferents, namely Pacinian afferents, is most sensitive. We show that this skin resonance can lead to a two-fold increase in the strength of the response of a simulated afferent population. Second, the rate at which vibrations propagate across the skin is dependent on the stimulus frequency and plateaus at 7 m/s. The resulting delay in neural activation across locations does not substantially blur the temporal patterning in simulated populations of afferents for frequencies less than 200 Hz, which has important implications about how vibratory frequency is encoded in the responses of somatosensory neurons. Third, we show that, despite the dependence of decay rate and propagation speed on frequency, the waveform of a complex vibration is well preserved as it travels across the skin. Our results suggest, then, that the propagation of surface waves promotes the encoding of spectrally complex vibrations as the entire neural population is exposed to essentially the same stimulus. We also discuss the implications of our results for biomechanical models of the skin.

  13. Non-linear wave loads and ship responses by a time-domain strip theory

    DEFF Research Database (Denmark)

    Xia, Jinzhu; Wang, Zhaohui; Jensen, Jørgen Juncher

    1998-01-01

    A non-linear time-domain strip theory for vertical wave loads and ship responses is presented. The theory is generalized from a rigorous linear time-domain strip theory representation. The hydrodynamic memory effect due to the free surface is approximated by a higher order differential equation. ...... and are systematically compared with the experimental results given by Watanabe et al. (1989, J. Soc. Naval Architects Japan, 166) and O’Dea et al. (1992, Proc. 19th Symp. on Naval Hydrodynamics). The agreement between the present predictions and the experiments is very encouraging....

  14. Retrieval of P wave Basin Response from Autocorrelation of Seismic Noise-Jakarta, Indonesia

    Science.gov (United States)

    Saygin, E.; Cummins, P. R.; Lumley, D. E.

    2016-12-01

    Indonesia's capital city, Jakarta, is home to a very large (over 10 million), vulnerable population and is proximate to known active faults, as well as to the subduction of Australian plate, which has a megathrust at abut 300 km distance, as well as intraslab seismicity extending to directly beneath the city. It is also located in a basin filled with a thick layer of unconsolidated and poorly consolidated sediment, which increases the seismic hazard the city is facing. Therefore, the information on the seismic velocity structure of the basin is crucial for increasing our knowledge of the seismic risk. We undertook a passive deployment of broadband seismographs throughout the city over a 3-month interval in 2013-2014, recording ambient seismic noise at over 90 sites for intervals of 1 month or more. Here we consider autocorrelations of the vertical component of the continuously recorded seismic wavefield across this dense network to image the shallow P wave velocity structure of Jakarta, Indonesia. Unlike the surface wave Green's functions used in ambient noise tomography, the vertical-component autocorrelograms are dominated by body wave energy that is potentially sensitive to sharp velocity contrasts, which makes them useful in seismic imaging. Results show autocorrelograms at different seismic stations with travel time variations that largely reflect changes in sediment thickness across the basin. We also confirm the validity our interpretation of the observed autocorrelation waveforms by conducting 2D finite difference full waveform numerical modeling for randomly distributed seismic sources to retrieve the reflection response through autocorrelation.

  15. Study of the filtration performance of a plain wave fabric filter using response surface methodology.

    Science.gov (United States)

    Qian, Fuping; Wang, Haigang

    2010-04-15

    The gas-solid two-phase flows in the plain wave fabric filter were simulated by computational fluid dynamics (CFD) technology, and the warps and wefts of the fabric filter were made of filaments with different dimensions. The numerical solutions were carried out using commercial computational fluid dynamics (CFD) code Fluent 6.1. The filtration performances of the plain wave fabric filter with different geometry parameters and operating condition, including the horizontal distance, the vertical distance and the face velocity were calculated. The effects of geometry parameters and operating condition on filtration efficiency and pressure drop were studied using response surface methodology (RSM) by means of the statistical software (Minitab V14), and two second-order polynomial models were obtained with regard to the effect of the three factors as stated above. Moreover, the models were modified by dismissing the insignificant terms. The results show that the horizontal distance, vertical distance and the face velocity all play an important role in influencing the filtration efficiency and pressure drop of the plane wave fabric filters. The horizontal distance of 3.8 times the fiber diameter, the vertical distance of 4.0 times the fiber diameter and Reynolds number of 0.98 are found to be the optimal conditions to achieve the highest filtration efficiency at the same face velocity, while maintaining an acceptable pressure drop.

  16. Transcriptional and microscopic analyses of citrus stem and root responses to Candidatus Liberibacter asiaticus infection.

    Directory of Open Access Journals (Sweden)

    Valente Aritua

    Full Text Available Huanglongbing (HLB is the most destructive disease that affects citrus worldwide. The disease has been associated with Candidatus Liberibacter. HLB diseased citrus plants develop a multitude of symptoms including zinc and copper deficiencies, blotchy mottle, corky veins, stunting, and twig dieback. Ca. L. asiaticus infection also seriously affects the roots. Previous study focused on gene expression of leaves and fruit to Ca. L. asiaticus infection. In this study, we compared the gene expression levels of stems and roots of healthy plants with those in Ca. L. asiaticus infected plants using microarrays. Affymetrix microarray analysis showed a total of 988 genes were significantly altered in expression, of which 885 were in the stems, and 111 in the roots. Of these, 551 and 56 were up-regulated, while 334 and 55 were down-regulated in the stem and root samples of HLB diseased trees compared to healthy plants, respectively. Dramatic differences in the transcriptional responses were observed between citrus stems and roots to Ca. L. asiaticus infection, with only 8 genes affected in both the roots and stems. The affected genes are involved in diverse cellular functions, including carbohydrate metabolism, cell wall biogenesis, biotic and abiotic stress responses, signaling and transcriptional factors, transportation, cell organization, protein modification and degradation, development, hormone signaling, metal handling, and redox. Microscopy analysis showed the depletion of starch in the roots of the infected plants but not in healthy plants. Collapse and thickening of cell walls were observed in HLB affected roots, but not as severe as in the stems. This study provides insight into the host response of the stems and roots to Ca. L. asiaticus infection.

  17. Proteomic and Physiological Analyses Reveal Putrescine Responses in Roots of Cucumber Stressed by NaCl

    Directory of Open Access Journals (Sweden)

    Yinghui Yuan

    2016-07-01

    Full Text Available Soil salinity is a major environmental constraint that threatens agricultural productivity. Different strategies have been developed to improve crop salt tolerance, among which the effects of polyamines have been well reported. To gain a better understanding of the cucumber (Cucumis sativus L. responses to NaCl and unravel the underlying mechanism of exogenous putrescine (Put alleviating salt-induced damage, comparative proteomic analysis was conducted on cucumber roots treated with NaCl and/or Put for 7 days. The results showed that exogenous Put restored the root growth inhibited by NaCl. 62 differentially expressed proteins implicated in various biological processes were successfully identified by MALDI-TOF/TOF MS. The four largest categories included proteins involved in defense response (24.2%, protein metabolism (24.2%, carbohydrate metabolism (19.4% and amino acid metabolism (14.5%. Exogenous Put up-regulated most identified proteins involved in carbohydrate metabolism, implying an enhancement in energy generation. Proteins involved in defense response and protein metabolism were differently regulated by Put, which indicated the roles of Put in stress resistance and proteome rearrangement. Put also increased the abundance of proteins involved in amino acid metabolism. Meanwhile, physiological analysis showed that Put could further up-regulated the levels of free amino acids in salt stressed-roots. In addition, Put also improved endogenous polyamines contents by regulating the transcription levels of key enzymes in polyamine metabolism. Taken together, these results suggest that Put may alleviate NaCl-induced growth inhibition through degradation of misfolded/damaged proteins, activation of stress defense, and the promotion of carbohydrate metabolism to generate more energy.

  18. The Women Employees within the Frame of Social Responsibility and an Analyse

    Directory of Open Access Journals (Sweden)

    Hulya Cagiran Kendirli

    2015-03-01

    Although Turkey signed CEDAW (Committee on the Elimination of Discrimination against Women which is a legally binding contract and many contracts of ILO which aimed at protecting the equality of men and women, and made some certain laws to protect the equality, it was the 126th country of 130 countries according to the Index of Gender Mainstreaming report published by WEF (World Economic Forum in 2013. In this regard, the need to replace women in the centre of social responsibility projects is inevitable.

  19. Proteomic analyses of iron-responsive, Clp-dependent changes in Staphylococcus aureus

    DEFF Research Database (Denmark)

    Farrand, Allison J; Friedman, David B; Reniere, Michelle L;

    2015-01-01

    Staphylococcus aureus is a frequent human pathogen that is capable of causing a wide range of life-threatening infections. A promising antibacterial target is the Clp proteolytic system, which performs the vital function of maintaining protein turnover within the cell. This system primarily impacts...... the bacterial response to various stresses by degrading specific proteins but can also regulate a number of physiological processes through protein degradation. A critical stress to which S. aureus must adapt during infection of a vertebrate host is nutrient iron limitation. We have previously shown...... of mutants inactivated for components of the Clp protease, including ClpP, ClpC and ClpX, in high- and low-iron conditions. Our results reveal numerous proteins altered in abundance in the clp mutants and provide new insights into the staphylococcal proteolytic network during nutrient iron limitation....

  20. Structural Response of Submerged Air-Backed Plates by Experimental and Numerical Analyses

    Directory of Open Access Journals (Sweden)

    Lloyd Hammond

    2000-01-01

    Full Text Available This paper presents the results of a series of small-scale underwater shock experiments that measured the structural responses of submerged, fully clamped, air-backed, steel plates to a range of high explosive charge sizes. The experimental results were subsequently used to validate a series of simulations using the coupled LS-DYNA/USA finite element/boundary element codes. The modelling exercise was complicated by a significant amount of local cavitation occurring in the fluid adjacent to the plate and difficulties in modelling the boundary conditions of the test plates. The finite element model results satisfactorily predicted the displacement-time history of the plate over a range of shock loadings although a less satisfactory correlation was achieved for the peak velocities. It is expected that the predictive capability of the finite element model will be significantly improved once hydrostatic initialisation can be fully utilised with the LS-DYNA/USA software.

  1. Quantitative proteomic analyses of the response of acidophilic microbial communities to different pH conditions.

    Science.gov (United States)

    Belnap, Christopher P; Pan, Chongle; Denef, Vincent J; Samatova, Nagiza F; Hettich, Robert L; Banfield, Jillian F

    2011-07-01

    Extensive genomic characterization of multi-species acid mine drainage microbial consortia combined with laboratory cultivation has enabled the application of quantitative proteomic analyses at the community level. In this study, quantitative proteomic comparisons were used to functionally characterize laboratory-cultivated acidophilic communities sustained in pH 1.45 or 0.85 conditions. The distributions of all proteins identified for individual organisms indicated biases for either high or low pH, and suggests pH-specific niche partitioning for low abundance bacteria and archaea. Although the proteome of the dominant bacterium, Leptospirillum group II, was largely unaffected by pH treatments, analysis of functional categories indicated proteins involved in amino acid and nucleotide metabolism, as well as cell membrane/envelope biogenesis were overrepresented at high pH. Comparison of specific protein abundances indicates higher pH conditions favor Leptospirillum group III, whereas low pH conditions promote the growth of certain archaea. Thus, quantitative proteomic comparisons revealed distinct differences in community composition and metabolic function of individual organisms during different pH treatments. Proteomic analysis revealed other aspects of community function. Different numbers of phage proteins were identified across biological replicates, indicating stochastic spatial heterogeneity of phage outbreaks. Additionally, proteomic data were used to identify a previously unknown genotypic variant of Leptospirillum group II, an indication of selection for a specific Leptospirillum group II population in laboratory communities. Our results confirm the importance of pH and related geochemical factors in fine-tuning acidophilic microbial community structure and function at the species and strain level, and demonstrate the broad utility of proteomics in laboratory community studies.

  2. Comparative analyses reveal potential uses of Brachypodium distachyon as a model for cold stress responses in temperate grasses

    Directory of Open Access Journals (Sweden)

    Li Chuan

    2012-05-01

    Full Text Available Abstract Background Little is known about the potential of Brachypodium distachyon as a model for low temperature stress responses in Pooideae. The ice recrystallization inhibition protein (IRIP genes, fructosyltransferase (FST genes, and many C-repeat binding factor (CBF genes are Pooideae specific and important in low temperature responses. Here we used comparative analyses to study conservation and evolution of these gene families in B. distachyon to better understand its potential as a model species for agriculturally important temperate grasses. Results Brachypodium distachyon contains cold responsive IRIP genes which have evolved through Brachypodium specific gene family expansions. A large cold responsive CBF3 subfamily was identified in B. distachyon, while CBF4 homologs are absent from the genome. No B. distachyon FST gene homologs encode typical core Pooideae FST-motifs and low temperature induced fructan accumulation was dramatically different in B. distachyon compared to core Pooideae species. Conclusions We conclude that B. distachyon can serve as an interesting model for specific molecular mechanisms involved in low temperature responses in core Pooideae species. However, the evolutionary history of key genes involved in low temperature responses has been different in Brachypodium and core Pooideae species. These differences limit the use of B. distachyon as a model for holistic studies relevant for agricultural core Pooideae species.

  3. Simulation of Electromagnetic Wave Logging Response in Deviated Wells Based on Vector Finite Element Method

    Institute of Scientific and Technical Information of China (English)

    LV Wei-Guo; CHU Zhao-Tan; ZHAO Xiao-Qing; FAN Yu-Xiu; SONG Ruo-Long; HAN Wei

    2009-01-01

    The vector finite element method of tetrahedral elements is used to model 3D electromagnetic wave logging response. The tangential component of the vector field at the mesh edges is used as a degree of freedom to overcome the shortcomings of node-based finite element methods. The algorithm can simulate inhomogeneous media with arbitrary distribution of conductivity and magnetic permeability. The electromagnetic response of well logging tools are studied in dipping bed layers with the borehole and invasion included. In order to simulate realistic logging tools, we take the transmitter antennas consisting of circular wire loops instead of magnetic dipoles. We also investigate the apparent resistivity of inhomogeneous formation for different dip angles.

  4. Study on Short-term Variability of Ship Responses in Waves

    DEFF Research Database (Denmark)

    Nielsen, Ulrik Dam; Iseki, Toshio

    2015-01-01

    Short-term variability of ship responses is investigated by cross-spectrum analysis. In a steady state condition, it is well known that a certain length of sampled data is required for stable results of the spectral analysis. However, the phase lag between responses, in terms of the phase angle...... of the cross-spectra, has not been discussed in detail. Using long stationary time series, the transition of amplitudes and relative phase angles of the cross-spectra has been investigated by iterative analyzes with a few seconds of time shifting. In the results, the short-term variability of the relative...... phase angle was observed. In effect, the variability may compromise the accuracy of the wave buoy analogy....

  5. Response Mechanism for Surface Acoustic Wave Gas Sensors Based on Surface-Adsorption

    Directory of Open Access Journals (Sweden)

    Jiansheng Liu

    2014-04-01

    Full Text Available A theoretical model is established to describe the response mechanism of surface acoustic wave (SAW gas sensors based on physical adsorption on the detector surface. Wohljent’s method is utilized to describe the relationship of sensor output (frequency shift of SAW oscillator and the mass loaded on the detector surface. The Brunauer-Emmett-Teller (BET formula and its improved form are introduced to depict the adsorption behavior of gas on the detector surface. By combining the two methods, we obtain a theoretical model for the response mechanism of SAW gas sensors. By using a commercial SAW gas chromatography (GC analyzer, an experiment is performed to measure the frequency shifts caused by different concentration of dimethyl methylphosphonate (DMMP. The parameters in the model are given by fitting the experimental results and the theoretical curve agrees well with the experimental data.

  6. Analysing and combining atmospheric general circulation model simulations forced by prescribed SST: northern extratropical response

    Directory of Open Access Journals (Sweden)

    K. Maynard

    2001-06-01

    Full Text Available The ECHAM 3.2 (T21, ECHAM 4 (T30 and LMD (version 6, grid-point resolution with 96 longitudes × 72 latitudes atmospheric general circulation models were integrated through the period 1961 to 1993 forced with the same observed Sea Surface Temperatures (SSTs as compiled at the Hadley Centre. Three runs were made for each model starting from different initial conditions. The mid-latitude circulation pattern which maximises the covariance between the simulation and the observations, i.e. the most skilful mode, and the one which maximises the covariance amongst the runs, i.e. the most reproducible mode, is calculated as the leading mode of a Singular Value Decomposition (SVD analysis of observed and simulated Sea Level Pressure (SLP and geopotential height at 500 hPa (Z500 seasonal anomalies. A common response amongst the different models, having different resolution and parametrization should be considered as a more robust atmospheric response to SST than the same response obtained with only one model. A robust skilful mode is found mainly in December-February (DJF, and in June-August (JJA. In DJF, this mode is close to the SST-forced pattern found by Straus and Shukla (2000 over the North Pacific and North America with a wavy out-of-phase between the NE Pacific and the SE US on the one hand and the NE North America on the other. This pattern evolves in a NAO-like pattern over the North Atlantic and Europe (SLP and in a more N-S tripole on the Atlantic and European sector with an out-of-phase between the middle Europe on the one hand and the northern and southern parts on the other (Z500. There are almost no spatial shifts between either field around North America (just a slight eastward shift of the highest absolute heterogeneous correlations for SLP relative to the Z500 ones. The time evolution of the SST-forced mode is moderatly to strongly related to the ENSO/LNSO events but the spread amongst the ensemble of runs is not systematically related

  7. Analysing and combining atmospheric general circulation model simulations forced by prescribed SST. Northern extra tropical response

    Energy Technology Data Exchange (ETDEWEB)

    Moron, V. [Universite' de Provence, UFR des sciences geographiques et de l' amenagement, Aix-en-Provence (France); Navarra, A. [Istituto Nazionale di Geofisica e Vulcanologia, Bologna (Italy); Ward, M. N. [University of Oklahoma, Cooperative Institute for Mesoscale Meteorological Studies, Norman OK (United States); Foland, C. K. [Hadley Center for Climate Prediction and Research, Meteorological Office, Bracknell (United Kingdom); Friederichs, P. [Meteorologisches Institute des Universitaet Bonn, Bonn (Germany); Maynard, K.; Polcher, J. [Paris Universite' Pierre et Marie Curie, Paris (France). Centre Nationale de la Recherche Scientifique, Laboratoire de Meteorologie Dynamique, Paris

    2001-08-01

    The ECHAM 3.2 (T21), ECHAM 4 (T30) and LMD (version 6, grid-point resolution with 96 longitudes x 72 latitudes) atmospheric general circulation models were integrated through the period 1961 to 1993 forced with the same observed Sa Surface Temperatures (SSTs) as compiled at the Hadley Centre. Three runs were made for each model starting from different initial conditions. The mid-latitude circulation pattern which maximises the covariance between the simulation and the observations, i.e. the most skilful mode, and the one which maximises the covariance amongst the runs, i.e. the most reproducible mode, is calculated as the leading mode of a Singular Value Decomposition (SVD) analysis of observed and simulated Sea Level Pressure (SLP) and geo potential height at 500 hPa (Z500) seasonal anomalies. A common response amongst the different models, having different resolution and parametrization should be considered as a more robust atmospheric response to SST than the sam response obtained with only one model A robust skilful mode is found mainly in December-February (DJF), and in June-August (JJA). In DJF, this mode is close to the SST-forced pattern found by Straus nd Shukla (2000) over the North Pacific and North America with a wavy out-of-phase between the NE Pacific and the SE US on the one hand and the NE North America on the other. This pattern evolves in a NAO-like pattern over the North Atlantic and Europe (SLP) and in a more N-S tripote on the Atlantic and European sector with an out-of-phase between the middle Europe on the one hand and the northern and southern parts on the other (Z500). There are almost no spatial shifts between either field around North America (just a slight eastward shift of the highest absolute heterogenous correlations for SLP relative to the Z500 ones). The time evolution of the SST-forced mode is moderately to strongly related to the ENSO/LNSO events but the spread amongst the ensemble of runs is not systematically related at all to

  8. Local increase of anticyclonic wave activity over northern Eurasia under amplified Arctic warming: WAVE ACTIVITY RESPONSE TO ARCTIC MELTING

    Energy Technology Data Exchange (ETDEWEB)

    Xue, Daokai [School of Atmospheric Sciences, Nanjing University, Nanjing China; Lu, Jian [Atmospheric Sciences and Global Change Division, Pacific Northwest National Laboratory, Richland Washington USA; Sun, Lantao [CIRES, University of Colorado Boulder, Boulder Colorado USA; PSD, ESRL, NOAA, Boulder Colorado USA; Chen, Gang [Department of Earth and Atmospheric Sciences, UCLA, Los Angeles California USA; Zhang, Yaocun [School of Atmospheric Sciences, Nanjing University, Nanjing China

    2017-04-10

    In an attempt to resolve the controversy as to whether Arctic sea ice loss leads to more mid-latitude extremes, a metric of finite-amplitude wave activity is adopted to quantify the midlatitude wave activity and its change during the observed period of the drastic Arctic sea ice decline in both ERA Interim reanalysis data and a set of AMIP-type of atmospheric model experiments. Neither the experiment with the trend in the SST or that with the declining trend of Arctic sea ice can simulate the sizable midlatitude-wide reduction in the total wave activity (Ae) observed in the reanalysis, leaving its explanation to the atmospheric internal variability. On the other hand, both the diagnostics of the flux of the local wave activity and the model experiments lend evidence to a possible linkage between the sea ice loss near the Barents and Kara seas and the increasing trend of anticyclonic local wave activity over the northern part of the central Eurasia and the associated impacts on the frequency of temperature extremes.

  9. Wave Data Analysis

    DEFF Research Database (Denmark)

    Alikhani, Amir; Frigaard, Peter; Burcharth, Hans F.

    1998-01-01

    The data collected over the course of the experiment must be analysed and converted into a form suitable for its intended use. Type of analyses range from simple to sophisticated. Depending on the particular experiment and the needs of the researcher. In this study three main part of irregular wave...... data analyses are presented e.g. Time Domain (Statistical) Analyses, Frequency Domain (Spectral) Analyses and Wave Reflection Analyses. Random wave profile and definitions of representative waves, distributions of individual wave height and wave periods and spectra of sea waves are presented....

  10. Cross-species toxicogenomic analyses and phenotypic anchoring in response to groundwater low-level pollution.

    Science.gov (United States)

    Porreca, Immacolata; D'Angelo, Fulvio; Gentilcore, Daniela; Carchia, Emanuele; Amoresano, Angela; Affuso, Andrea; Ceccarelli, Michele; De Luca, Pasquale; Esposito, Libera; Guadagno, Francesco M; Mallardo, Massimo; Nardone, Antonio; Maccarone, Sergio; Pane, Francesca; Scarfò, Marzia; Sordino, Paolo; De Felice, Mario; Ambrosino, Concetta

    2014-12-05

    Comparison of toxicogenomic data facilitates the identification of deregulated gene patterns and maximizes health risk prediction in human. Here, we performed phenotypic anchoring on the effects of acute exposure to low-grade polluted groundwater using mouse and zebrafish. Also, we evaluated two windows of chronic exposure in mouse, starting in utero and at the end of lactation. Bioinformatic analysis of livers microarray data showed that the number of deregulated biofunctions and pathways is higher after acute exposure, compared to the chronic one. It also revealed specific profiles of altered gene expression in all treatments, pointing to stress response/mitochondrial pathways as major players of environmental toxicity. Of note, dysfunction of steroid hormones was also predicted by bioinformatic analysis and verified in both models by traditional approaches, serum estrogens measurement and vitellogenin mRNA determination in mice and zebrafish, respectively. In our report, phenotypic anchoring in two vertebrate model organisms highlights the toxicity of low-grade pollution, with varying susceptibility based on exposure window. The overlay of zebrafish and mice deregulated pathways, more than single genes, is useful in risk identification from chemicals implicated in the observed effects.

  11. Transcriptome analyses of the honeybee response to Nosema ceranae and insecticides.

    Directory of Open Access Journals (Sweden)

    Julie Aufauvre

    Full Text Available Honeybees (Apis mellifera are constantly exposed to a wide variety of environmental stressors such as parasites and pesticides. Among them, Nosema ceranae and neurotoxic insecticides might act in combination and lead to a higher honeybee mortality. We investigated the molecular response of honeybees exposed to N. ceranae, to insecticides (fipronil or imidacloprid, and to a combination of both stressors. Midgut transcriptional changes induced by these stressors were measured in two independent experiments combining a global RNA-Seq transcriptomic approach with the screening of the expression of selected genes by quantitative RT-PCR. Although N. ceranae-insecticide combinations induced a significant increase in honeybee mortality, we observed that they did not lead to a synergistic effect. According to gene expression profiles, chronic exposure to insecticides had no significant impact on detoxifying genes but repressed the expression of immunity-related genes. Honeybees treated with N. ceranae, alone or in combination with an insecticide, showed a strong alteration of midgut immunity together with modifications affecting cuticle coatings and trehalose metabolism. An increasing impact of treatments on gene expression profiles with time was identified suggesting an absence of stress recovery which could be linked to the higher mortality rates observed.

  12. Impact analyses for negative flexural responses (hogging) in railway prestressed concrete sleepers

    Science.gov (United States)

    Kaewunruen, S.; Ishida, T.; Remennikov, AM

    2016-09-01

    By nature, ballast interacts with railway concrete sleepers in order to provide bearing support to track system. Most train-track dynamic models do not consider the degradation of ballast over time. In fact, the ballast degradation causes differential settlement and impact forces acting on partial and unsupported tracks. Furthermore, localised ballast breakages underneath railseat increase the likelihood of centrebound cracks in concrete sleepers due to the unbalanced support under sleepers. This paper presents a dynamic finite element model of a standard-gauge concrete sleeper in a track system, taking into account the tensionless nature of ballast support. The finite element model was calibrated using static and dynamic responses in the past. In this paper, the effects of centre-bound ballast support on the impact behaviours of sleepers are highlighted. In addition, it is the first to demonstrate the dynamic effects of sleeper length on the dynamic design deficiency in concrete sleepers. The outcome of this study will benefit the rail maintenance criteria of track resurfacing in order to restore ballast profile and appropriate sleeper/ballast interaction.

  13. Atmospheric Layers in Response to the Propagation of Gravity Waves under Nonisothermal, Wind-shear, and Dissipative Conditions

    Directory of Open Access Journals (Sweden)

    John Z. G. Ma

    2016-03-01

    Full Text Available We study the atmospheric structure in response to the propagation of gravity waves under nonisothermal (nonzero vertical temperature gradient, wind-shear (nonzero vertical zonal/meridional wind speed gradients, and dissipative (nonzero molecular viscosity and thermal conduction conditions. As an alternative to the “complex wave-frequency” model proposed by Vadas and Fritts, we employ the traditional “complex vertical wave-number” approach to solving an eighth-order complex polynomial dispersion equation. The empirical neutral atmospheric models of NRLMSISE-00 and HWM93 are employed to provide mean-field properties. In response to the propagation of gravity waves, the atmosphere is driven into three sandwich-like layers: the adiabatic layer (0–130 km, the dissipation layer (130–230 km and the pseudo-adiabatic layer (above 230 km. In the lower layer, (extended-Hines’ mode or ordinary dissipative wave modes exist, whereas viscous dissipation and thermal conduction fail to exert perceptible influences; in the middle layer, Hines’ mode ceases to exist, and both ordinary and extraordinary dissipative wave modes flourish; in the top layer, only extraordinary wave modes survive, and dissipations affect the real part of the vertical wavenumber ( m r substantially; however, they contribute little to the imaginary part, which is the vertical growth rate ( m i . We also analyze the transition of Hines’ classical mode to ordinary dissipative wave modes, describe both the upward and downward modes of gravity waves and illustrate nonisothermal and wind-shear effects on the propagation of gravity waves of different modes.

  14. Millimeter-wave response and linewidth of Josephson oscillations in YBa2Cu3O7 step-edge junctions

    DEFF Research Database (Denmark)

    Divin, Yu. Ya.; Andreev, A. V.; Fischer, Gerd Michael

    1993-01-01

    We have studied the response of YBa2Cu3O7 step-edge junctions to low-intensity millimeter-wave radiation in the temperature range from 4 to 80 K. The linewidth of the Josephson oscillations derived from the resonant part of the response at voltages V congruent-to (h/2e)f is shown to be determined...

  15. Response of water temperature to surface wave effects in the Baltic Sea: simulations with the coupled NEMO-WAM model

    Science.gov (United States)

    Alari, Victor; Staneva, Joanna; Breivik, Øyvind; Bidlot, Jean-Raymond; Mogensen, Kristian; Janssen, Peter

    2016-04-01

    The effects of wind waves on the Baltic Sea water temperature has been studied by coupling the hydrodynamical model NEMO with the wave model WAM. The wave forcing terms that have been taken into consideration are: Stokes-Coriolis force, seastate dependent energy flux and sea-state dependent momentum flux. The combined role of these processes as well as their individual contributions on simulated temperature is analysed. The results indicate a pronounced effect of waves on surface temperature, on the distribution of vertical temperature and on upwellinǵs. In northern parts of the Baltic Sea a warming of the surface layer occurs in the wave included simulations. This in turn reduces the cold bias between simulated and measured data. The warming is primarily caused by sea-state dependent energy flux. Wave induced cooling is mostly observed in near coastal areas and is mainly due to Stokes-Coriolis forcing. The latter triggers effect of intensifying upwellings near the coasts, depending on the direction of the wind. The effect of sea-state dependent momentum flux is predominantly to warm the surface layer. During the summer the wave induced water temperature changes were up to 1 °C.

  16. Advanced vapor recognition materials for selective and fast responsive surface acoustic wave sensors: a review.

    Science.gov (United States)

    Afzal, Adeel; Iqbal, Naseer; Mujahid, Adnan; Schirhagl, Romana

    2013-07-17

    The necessity of selectively detecting various organic vapors is primitive not only with respect to regular environmental and industrial hazard monitoring, but also in detecting explosives to combat terrorism and for defense applications. Today, the huge arsenal of micro-sensors has revolutionized the traditional methods of analysis by, e.g. replacing expensive laboratory equipment, and has made the remote screening of atmospheric threats possible. Surface acoustic wave (SAW) sensors - based on piezoelectric crystal resonators - are extremely sensitive to even very small perturbations in the external atmosphere, because the energy associated with the acoustic waves is confined to the crystal surface. Combined with suitably designed molecular recognition materials SAW devices could develop into highly selective and fast responsive miniaturized sensors, which are capable of continuously monitoring a specific organic gas, preferably in the sub-ppm regime. For this purpose, different types of recognition layers ranging from nanostructured metal oxides and carbons to pristine or molecularly imprinted polymers and self-assembled monolayers have been applied in the past decade. We present a critical review of the recent developments in nano- and micro-engineered synthetic recognition materials predominantly used for SAW-based organic vapor sensors. Besides highlighting their potential to realize real-time vapor sensing, their limitations and future perspectives are also discussed.

  17. A time-localized response of wave growth process under turbulent winds

    Directory of Open Access Journals (Sweden)

    Z. Ge

    2007-06-01

    Full Text Available Very short time series (with lengths of approximately 40 s or 5~7 wave periods of wind velocity fluctuations and wave elevation were recorded simultaneously and investigated using the wavelet bispectral analysis. Rapid changes in the wave and wind spectra were detected, which were found to be intimately related to significant energy transfers through transient quadratic wind-wave and wave-wave interactions. A possible pattern of energy exchange between the wind and wave fields was further deduced. In particular, the generation and variation of the strong wave-induced perturbation velocity in the wind can be explained by the strengthening and diminishing of the associated quadratic interactions, which cannot be unveiled by linear theories. On small time scales, the wave-wave quadratic interactions were as active and effective in transferring energy as the wind-wave interactions. The results also showed that the wind turbulence was occasionally effective in transferring energy between the wind and the wave fields, so that the background turbulence in the wind cannot be completely neglected. Although these effects are all possibly significant over short times, the time-localized growth of the wave spectrum may not considerably affect the long-term process of wave development.

  18. Traveling wave effect on the seismic response of a steel arch bridge subjected to near fault ground motions

    Institute of Scientific and Technical Information of China (English)

    Xu Yan; George C Lee

    2007-01-01

    In the 1990s, several major earthquakes occurred throughout the world, with a common observation that near fault ground motion (NFGM) characteristics had a distinct impact on causing damage to civil engineering structures that could not be predicted by using far field ground motions. Since then, seismic responses of structures under NFGMs have been extensively examined, with most of the studies focusing on structures with relatively short fundamental periods, where the traveling wave effect does not need to be considered. However, for long span bridges, especially arch bridges, the traveling wave (only time delay considered) effect may be very distinct and is therefore important. In this paper, the results from a case study on the seismic response of a steel arch bridge under selected NFGMs is presented by considering the traveling wave effect with variable apparent velocities. The effects of fling step and long period pulses of NFGMs on the seismic responses of the arch bridge are also discussed.

  19. CHARADE: A characteristic code for calculating rate-dependent shock-wave response

    Energy Technology Data Exchange (ETDEWEB)

    Johnson, J.N.; Tonks, D.L.

    1991-01-01

    In this report we apply spatially one-dimensional methods and simple shock-tracking techniques to the solution of rate-dependent material response under flat-plate-impact conditions. This method of solution eliminates potential confusion of material dissipation with artificial dissipative effects inherent in finite-difference codes, and thus lends itself to accurate calculation of elastic-plastic deformation, shock-to-detonation transition in solid explosives, and shock-induced structural phase transformation. Equations are presented for rate-dependent thermoelastic-plastic deformation for (100) planar shock-wave propagation in materials of cubic symmetry (or higher). Specific numerical calculations are presented for polycrystalline copper using the mechanical threshold stress model of Follansbee and Kocks with transition to dislocation drag. A listing of the CHARADE (for characteristic rate dependence) code and sample input deck are given. 26 refs., 11 figs.

  20. Numerical Simulation of Dynamic Response of A Net Cage for Flatfish in Waves

    Institute of Scientific and Technical Information of China (English)

    桂福坤; 赵云鹏; 许条建; 关长涛

    2014-01-01

    A numerical model of flatfish cage is built based on the lumped mass method and the principle of rigid body kinematics. To validate the numerical model, a series of physical model tests are conducted in the wave flume. The numerical results correspond well with the data sets from physical model test. The effect of weight of bottom frame, height of fish net and net shape on motion responses of fish cage and tension force on mooring lines is then analyzed. The results indicate that the vertical displacements of float collar and bottom frame decrease with the increase in the weight of bottom frame; the maximum tension force on mooring lines increases with the increasing weight of bottom frame. The inclination angles of float collar and bottom frame decrease with the increasing net height; the maximum tension force increases obviously with the increase of net height.

  1. Numerical simulation of dynamic response of a net cage for flatfish in waves

    Science.gov (United States)

    Gui, Fu-kun; Zhao, Yun-peng; Xu, Tiao-jian; Guan, Chang-tao

    2014-03-01

    A numerical model of flatfish cage is built based on the lumped mass method and the principle of rigid body kinematics. To validate the numerical model, a series of physical model tests are conducted in the wave flume. The numerical results correspond well with the data sets from physical model test. The effect of weight of bottom frame, height of fish net and net shape on motion responses of fish cage and tension force on mooring lines is then analyzed. The results indicate that the vertical displacements of float collar and bottom frame decrease with the increase in the weight of bottom frame; the maximum tension force on mooring lines increases with the increasing weight of bottom frame. The inclination angles of float collar and bottom frame decrease with the increasing net height; the maximum tension force increases obviously with the increase of net height.

  2. Fault zone damage, nonlinear site response, and dynamic triggering associated with seismic waves

    Science.gov (United States)

    Wu, Chunquan

    My dissertation focuses primarily on the following three aspects associated with passing seismic waves in the field of earthquake seismology: temporal changes of fault zone properties, nonlinear site response, and dynamic triggering. I systematically analyze temporal changes of fault zone (FZ) site response along the Karadere-Duzce branch of the North Anatolian fault that ruptured during the 1999 Izmit and Duzce earthquake sequences. These results provide a bridge between the large-amplitude near-instantaneous changes and the lower-amplitude longer-duration variations observed in previous studies. The temporal changes measured from this high-resolution spectral ratio analysis also provide a refinement for the beginning of the longer more gradual process typically observed by analyzing repeating earthquakes. I use the same sliding-window spectral ratio technique to analyze temporal changes in site response associated with the strong ground motion of the Mw6.6 2004 Mid-Niigata earthquake sequence recorded by the borehole stations in Japanese Digital Strong-Motion Seismograph Network (KiK-Net). The results suggest that at a given site the input ground motion plays an important role in controlling both the coseismic change and postseismic recovery in site response. In a follow-up study, I apply the same sliding-window spectral ratio technique to surface and borehole strong motion records at 6 KiK-Net sites, and stack results associated with different earthquakes that produce similar PGAs. In some cases I observe a weak coseismic drop in the peak frequency when the PGA is as small as ˜20--30 Gal, and near instantaneous recovery after the passage of the direct S waves. The percentage of drop in the peak frequency starts to increase with increasing PGA values. A coseismic drop in the peak spectral ratio is also observed at 2 sites. When the PGA is larger than ˜60 Gal to more than 100 Gal, considerably stronger coseismic drops of the peak frequencies are observed

  3. Enhanced Doppler reflectometry power response: physical optics and 2D full wave modelling

    Science.gov (United States)

    Pinzón, J. R.; Happel, T.; Blanco, E.; Conway, G. D.; Estrada, T.; Stroth, U.

    2017-03-01

    The power response of a Doppler reflectometer is investigated by means of the physical optics model; a simple model which considers basic scattering processes at the reflection layer. Apart from linear and saturated scattering regimes, non-linear regimes with an enhanced backscattered power are found. The different regimes are characterized and understood based on analytical calculations. The power response is also studied with two-dimensional full wave simulations, where the enhanced backscattered power regimes are also found in qualitative agreement with the physical optics results. The ordinary and extraordinary modes are compared for the same angle of incidence, with the conclusion that the ordinary mode is better suited for Doppler reflectometry turbulence level measurements due to the linearity of its response. The scattering efficiency is studied and a first approximation to describe it is proposed. At the end, the application of the physical optics results to experimental data analysis is discussed. In particular, a formula to assess the linearity of Doppler reflectometry measurements is provided.

  4. Effects of N on Plant Response to Heat-wave: A Field Study with Prairie Vegetation

    Institute of Scientific and Technical Information of China (English)

    Dan Wang; Scott A. Heckathorn; Kumar Mainali; E. William Hamilton

    2008-01-01

    More intense, more frequent, and longer heat-waves are expected in the future due to global warming, which could have dramatic ecological impacts. Increasing nitrogen (N) availability and its dynamics will likely impact plant responses to heat stress and carbon (C) sequestration in terrestrial ecosystems. This field study examined the effects of N availability on plant response to heat-stress (HS) treatment in naturally-occurring vegetation. HS (5 d at ambient or 40.5 ℃) and N treatments (±N) were applied to 16 1 m2 plots in restored prairie vegetation dominated by Andropogon gerardii (warm-season C4 grass) and Solidago canadensis (warm-season C3 forb). Before, during, and after HS, air, canopy, and soil temperature were monitored; net CO2 assimilation (Pn), quantum yield of photosystem Ⅱ (φPsⅡ), stomatal conductance (gs), and leaf water potential (Ψw) of the dominant species and soil respiration (Rsolf) of each plot were measured daily during HS. One week after HS, plots were harvested, and C% and N% were determined for rhizosphere and bulk soil, and above-ground tissue (green/senescent leaf, stem, and flower). Photosynthetic N-use efficiency (PNUE) and N resorption rate (NRR) were calculated. HS decreased Pn, gs, Ψw, and PNUE for both species, and +N treatment generally increased these variables (±HS), but often slowed their poat-HS recovery. Aboveground biomass tended to decrease with HS in both species (and for green leaf mass in S. canadensis), but decrease with +N for ,4. gerardii and increase with +N for S. canadensis. For A. gerardii, HS tended to decrease N% in green tissues with +N, whereas in S. canadensis, HS increased N% in green leaves.Added N decreased NRR for A. gerardii and HS increased NRR for S. canadensis. These results suggest that heat waves,though transient, could have significant effects on plants, communities, and ecosystem N cycling, and N can influence the effect of heat waves.

  5. Shallow shear-wave velocity profiles and site response characteristics from microtremor array measurements in Metro Manila, the Philippines

    Science.gov (United States)

    Grutas, Rhommel; Yamanaka, Hiroaki

    2012-07-01

    This paper presents the outcome of reconnaissance surveys in metropolitan Manila (Metro Manilla), the Philippines, with the aim of mapping shallow shear-wave velocity structures. Metro Manila is a seismically active and densely populated region that is in need of detailed investigation of the subsurface structures, to assess local site effects in seismic hazard estimation. We conducted microtremor array observations and used the spatial autocorrelation method to estimate the shear-wave profiles at 32 sites in major geological settings in Metro Manila. We applied a hybrid genetic simulated annealing algorithm to invert phase velocity data from the spatial autocorrelation method to generate shear-wave velocity models near the global best-fit solution. The comparison between the inferred shear-wave velocity profiles and PS logging showed good agreement in terms of the fundamental mode of Rayleigh waves and site responses. Then, we utilised the inferred shear-wave velocity profiles to compute the site amplifications with reference to the motion in engineering bedrock. Subsequently, the site amplifications have been grouped, based on NEHRP site classes. The amplification factor has also been compared with the average shear-wave velocity of the upper 30m at each site, to produce a power-law regression equation that can be used as a starting basis for further site-effects evaluation in the metropolis.

  6. Analyse - technologies; Analyse - technologies

    Energy Technology Data Exchange (ETDEWEB)

    Roudil, D.; Chevalier, M.; Cormont, Ph.; Viala, F.; Kopp, Ch.; Peillet, O.; Chatroux, D.; Lausenaz, Y.; Villard, J.F.; Bruel, L.; Berhouet, F.; Chartier, F.; Aubert, M.; Blanchet, P.; Steiner, F.; Puech, M.H.; Bienvenu, Ph.; Noire, M.H.; Bouzon, C.; Schrive, L

    1999-07-01

    In this chapter of the DCC 1999 scientific report, the following theoretical studies are detailed: emulsions characterization by ultrasonics, high resolution wavelength meter, optimization methodology for diffractive and hybrid optic system, reliability for fast switches in power electronics, study of cesium isolation in irradiated fuels, chemical optodes based on evanescent wave absorption, radionuclides (Zirconium 93 and molybdenum 93) determination in irradiated fuels processing effluents, study of viscous liquid ultrafiltration using supercritical CO{sub 2} fluid. (A.L.B.)

  7. Research the dynamical characteristics of slow deformation waves as a rock massif response to explosions during its outworking

    Science.gov (United States)

    Hachay, Olga; Khachay, Oleg; Shipeev, Oleg

    2015-04-01

    As a result of long-term natural geomechanics and geophysical observation data on mines of complex ore rocks, generalization of the non-linear reaction of rock massif to heavy dynamic influences have been established. In addition, pendulum type waves have been observed and the sources of them have been located inside geoblocks of different hierarchic levels (Oparin et al., 2010). At the same time, these waves propagate with wide low (compared with seismic waves) velocity values (Kurlenja et al., 1993; Oparin et al., 2006). Research into the massif state with the use of the dynamic systems theory approach (Naimark et al., 2009; Chulichkov, 2003; Hachay et al., 2010) has been developed to ascertain the criteria of dissipative regimes changing for real rock massifs, which are under heavy man-caused influence. To realize such research we used the data from the seismic record of the Tashtagol mine for the two-year period from June 2006 up to June 2008. We used the space-time coordinates for all dynamic massif event responses, which occurred during that period inside the mine space and for the explosions - values fixed by seismic station energy (Hachay et al., 2010). The phase diagrams of the massif state for the northern and southern parts of the mine space were plotted in coordinates Ev(t) and d(Ev(t))/dt, t - time - in parts of 24 hours, Ev - the dissipated massive seismic energy - in joules. Hachay et al., (2010) analysed the morphology of seismic response phase trajectories on the explosion influences during different serial intervals in the southern part of the mine. In that period, according to data for different explosions in the mine, the majority of the total energy had been injected into the southern part of the mine. Moreover, at the end of 2007, just in the southern part, the strongest rock burst during the whole history of the working mine happened. We developed a new processing method of seismological information in real, which we can use directly in the

  8. Examining the response of larch needle carbohydrates to climate using compound-specific δ13C and concentration analyses

    Science.gov (United States)

    Rinne, Katja T.; Saurer, Matthias; Kirdyanov, Alexander V.; Bryukhanova, Marina V.; Prokushkin, Anatoly S.; Churakova Sidorova, Olga V.; Siegwolf, Rolf T. W.

    2016-04-01

    Little is known about the dynamics of concentrations and carbon isotope ratios of individual carbohydrates in leaves in response to climatic and physiological factors. Improved knowledge of the isotopic ratio in sugars will enhance our understanding of the tree ring isotope ratio and will help to decipher environmental conditions in retrospect more reliably. Carbohydrate samples from larch (Larix gmelinii) needles of two sites in the continuous permafrost zone of Siberia with differing growth conditions were analysed with the Compound-Specific Isotope Analysis (CSIA). We compared concentrations and carbon isotope values (δ13C) of sucrose, fructose, glucose and pinitol combined with phenological data. The results for the variability of the needle carbohydrates show high dynamics with distinct seasonal characteristics between and within the studied years with a clear link to the climatic conditions, particularly vapour pressure deficit. Compound-specific differences in δ13C values as a response to climate were detected. The δ13C of pinitol, which contributes up to 50% of total soluble carbohydrates, was almost invariant during the whole growing season. Our study provides the first in-depth characterization of compound-specific needle carbohydrate isotope variability, identifies involved mechanisms and shows the potential of such results for linking tree physiological responses to different climatic conditions.

  9. Analyses and simulations of the upper ocean's response to Hurricane Felix at the Bermuda Testbed Mooring site: 13-23 August 1995

    Science.gov (United States)

    Zedler, S. E.; Dickey, T. D.; Doney, S. C.; Price, J. F.; Yu, X.; Mellor, G. L.

    2002-12-01

    The center of Hurricane Felix passed 85 km to the southwest of the Bermuda Testbed Mooring (BTM; 31°44'N, 64°10'W) site on 15 August 1995. Data collected in the upper ocean from the BTM during this encounter provide a rare opportunity to investigate the physical processes that occur in a hurricane's wake. Data analyses indicate that the storm caused a large increase in kinetic energy at near-inertial frequencies, internal gravity waves in the thermocline, and inertial pumping, mixed layer deepening, and significant vertical redistribution of heat, with cooling of the upper 30 m and warming at depths of 30-70 m. The temperature evolution was simulated using four one-dimensional mixed layer models: Price-Weller-Pinkel (PWP), K Profile Parameterization (KPP), Mellor-Yamada 2.5 (MY), and a modified version of MY2.5 (MY2). The primary differences in the model results were in their simulations of temperature evolution. In particular, when forced using a drag coefficient that had a linear dependence on wind speed, the KPP model predicted sea surface cooling, mixed layer currents, and the maximum depth of cooling closer to the observations than any of the other models. This was shown to be partly because of a special parameterization for gradient Richardson number (RgKPP) shear instability mixing in response to resolved shear in the interior. The MY2 model predicted more sea surface cooling and greater depth penetration of kinetic energy than the MY model. In the MY2 model the dissipation rate of turbulent kinetic energy is parameterized as a function of a locally defined Richardson number (RgMY2) allowing for a reduction in dissipation rate for stable Richardson numbers (RgMY2) when internal gravity waves are likely to be present. Sensitivity simulations with the PWP model, which has specifically defined mixing procedures, show that most of the heat lost from the upper layer was due to entrainment (parameterized as a function of bulk Richardson number RbPWP), with the

  10. Waves in the Red Sea: Response to monsoonal and mountain gap winds

    KAUST Repository

    Ralston, David K.

    2013-08-01

    An unstructured grid, phase-averaged wave model forced with winds from a high resolution atmospheric model is used to evaluate wind wave conditions in the Red Sea over an approximately 2-year period. The Red Sea lies in a narrow rift valley, and the steep topography surrounding the basin steers the dominant wind patterns and consequently the wave climate. At large scales, the model results indicated that the primary seasonal variability in waves was due to the monsoonal wind reversal. During the winter, monsoon winds from the southeast generated waves with mean significant wave heights in excess of 2. m and mean periods of 8. s in the southern Red Sea, while in the northern part of the basin waves were smaller, shorter period, and from northwest. The zone of convergence of winds and waves typically occurred around 19-20°N, but the location varied between 15 and 21.5°N. During the summer, waves were generally smaller and from the northwest over most of the basin. While the seasonal winds oriented along the axis of the Red Sea drove much of the variability in the waves, the maximum wave heights in the simulations were not due to the monsoonal winds but instead were generated by localized mountain wind jets oriented across the basin (roughly east-west). During the summer, a mountain wind jet from the Tokar Gap enhanced the waves in the region of 18 and 20°N, with monthly mean wave heights exceeding 2. m and maximum wave heights of 14. m during a period when the rest of the Red Sea was relatively calm. Smaller mountain gap wind jets along the northeast coast created large waves during the fall and winter, with a series of jets providing a dominant source of wave energy during these periods. Evaluation of the wave model results against observations from a buoy and satellites found that the spatial resolution of the wind model significantly affected the quality of the wave model results. Wind forcing from a 10-km grid produced higher skills for waves than winds from a

  11. Quantitative analyses at baseline and interim PET evaluation for response assessment and outcome definition in patients with malignant pleural mesothelioma.

    Science.gov (United States)

    Lopci, Egesta; Zucali, Paolo Andrea; Ceresoli, Giovanni Luca; Perrino, Matteo; Giordano, Laura; Gianoncelli, Letizia; Lorenzi, Elena; Gemelli, Maria; Santoro, Armando; Chiti, Arturo

    2015-04-01

    Quantitative analyses on FDG PET for response assessment are increasingly used in clinical studies, particularly with respect to tumours in which radiological assessment is challenging and complete metabolic response is rarely achieved after treatment. A typical example is malignant pleural mesothelioma (MPM), an aggressive tumour originating from mesothelial cells of the pleura. We present our results concerning the use of semiquantitative and quantitative parameters, evaluated at the baseline and interim PET examinations, for the prediction of treatment response and disease outcome in patients with MPM. We retrospectively analysed data derived from 131 patients (88 men, 43 women; mean age 66 years) with MPM who were referred to our institution for treatment between May 2004 and July 2013. Patients were investigated using FDG PET at baseline and after two cycles of pemetrexed-based chemotherapy. Responses were determined using modified RECIST criteria based on the best CT response after treatment. Disease control rate, progression-free survival (PFS) and overall survival (OS) were calculated for the whole population and were correlated with semiquantitative and quantitative parameters evaluated at the baseline and interim PET examinations; these included SUVmax, total lesion glycolysis (TLG), percentage change in SUVmax (ΔSUVmax) and percentage change in TLG (ΔTLG). Disease control was achieved in 84.7 % of the patients, and median PFS and OS for the entire cohort were 7.2 and 14.3 months, respectively. The log-rank test showed a statistically significant difference in PFS between patients with radiological progression and those with partial response (PR) or stable disease (SD) (1.8 vs. 8.6 months, p < 0.001). Baseline SUVmax and TLG showed a statistically significant correlation with PFS and OS (p < 0.001). In the entire population, both ΔSUVmax and ΔTLG were correlated with disease control based on best CT response (p < 0.001). ΔSUVmax was

  12. Quantitative analyses at baseline and interim PET evaluation for response assessment and outcome definition in patients with malignant pleural mesothelioma

    Energy Technology Data Exchange (ETDEWEB)

    Lopci, Egesta; Chiti, Arturo [Humanitas Research Hospital, Nuclear Medicine Department, Rozzano, Milan (Italy); Zucali, Paolo Andrea; Perrino, Matteo; Gianoncelli, Letizia; Lorenzi, Elena; Gemelli, Maria; Santoro, Armando [Humanitas Research Hospital, Oncology, Rozzano (Italy); Ceresoli, Giovanni Luca [Humanitas Gavazzeni, Oncology, Bergamo (Italy); Giordano, Laura [Humanitas Research Hospital, Biostatistics, Rozzano (Italy)

    2015-04-01

    Quantitative analyses on FDG PET for response assessment are increasingly used in clinical studies, particularly with respect to tumours in which radiological assessment is challenging and complete metabolic response is rarely achieved after treatment. A typical example is malignant pleural mesothelioma (MPM), an aggressive tumour originating from mesothelial cells of the pleura. We present our results concerning the use of semiquantitative and quantitative parameters, evaluated at the baseline and interim PET examinations, for the prediction of treatment response and disease outcome in patients with MPM. We retrospectively analysed data derived from 131 patients (88 men, 43 women; mean age 66 years) with MPM who were referred to our institution for treatment between May 2004 and July 2013. Patients were investigated using FDG PET at baseline and after two cycles of pemetrexed-based chemotherapy. Responses were determined using modified RECIST criteria based on the best CT response after treatment. Disease control rate, progression-free survival (PFS) and overall survival (OS) were calculated for the whole population and were correlated with semiquantitative and quantitative parameters evaluated at the baseline and interim PET examinations; these included SUV{sub max}, total lesion glycolysis (TLG), percentage change in SUV{sub max} (ΔSUV{sub max}) and percentage change in TLG (ΔTLG). Disease control was achieved in 84.7 % of the patients, and median PFS and OS for the entire cohort were 7.2 and 14.3 months, respectively. The log-rank test showed a statistically significant difference in PFS between patients with radiological progression and those with partial response (PR) or stable disease (SD) (1.8 vs. 8.6 months, p < 0.001). Baseline SUV{sub max} and TLG showed a statistically significant correlation with PFS and OS (p < 0.001). In the entire population, both ΔSUV{sub max} and ΔTLG were correlated with disease control based on best CT response (p < 0

  13. Observations and analyses of upper ocean responses to tropical storms and hurricanes in the vicinity of Bermuda

    Science.gov (United States)

    Black, W. J.; Dickey, T. D.

    2008-08-01

    A circular region within a radius of 400 km of Bermuda has been struck by 188 tropical storms or hurricanes from 1851 through 2005 and by 20 since 1995. Here we describe new direct and remote sensing observations and analyses of recent events near the Bermuda Testbed Mooring including Hurricane Fabian (2003), Tropical Storm Harvey (2005) and Hurricane Nate (2005). The most impressive upper ocean response of the recent events was produced by Hurricane Fabian when SST cooling exceeded 3.5°C, vertical mixing occurred to a depth of greater than 130 m, and upper ocean currents reached 100 cm s-1. Fabian also triggered an ocean color event visible in SeaWiFS satellite images. Related implications include improved estimates of the roles of tropical cyclones in driving meridional overturning circulation (MOC) and testing of hypotheses concerning warming of the tropical oceans which could cause more intense tropical storms and hurricanes.

  14. Analyses of potential predictive markers and survival data for a response to sunitinib in patients with metastatic renal cell carcinoma.

    Directory of Open Access Journals (Sweden)

    Juana Dornbusch

    Full Text Available BACKGROUND: Patients with metastatic clear cell renal cell carcinoma (ccRCC are frequently treated with tyrosine kinase inhibitors (TKI such as sunitinib. It inhibits angiogenic pathways by mainly targeting the receptors of VEGF and PDGF. In ccRCC, angiogenesis is characterized by the inactivation of the von Hippel-Lindau gene (VHL which in turn leads to the induction of HIF1α target genes such as CA9 and VEGF. Furthermore, the angiogenic phenotype of ccRCC is also reflected by endothelial markers (CD31, CD34 or other tumor-promoting factors like Ki67 or survivin. METHODS: Tissue microarrays from primary tumor specimens of 42 patients with metastatic ccRCC under sunitinib therapy were immunohistochemically stained for selected markers related to angiogenesis. The prognostic and predictive potential of theses markers was assessed on the basis of the objective response rate which was evaluated according to the RECIST criteria after 3, 6, 9 months and after last report (12-54 months of sunitinib treatment. Additionally, VHL copy number and mutation analyses were performed on DNA from cryo-preserved tumor tissues of 20 ccRCC patients. RESULTS: Immunostaining of HIF-1α, CA9, Ki67, CD31, pVEGFR1, VEGFR1 and -2, pPDGFRα and -β was significantly associated with the sunitinib response after 6 and 9 months as well as last report under therapy. Furthermore, HIF-1α, CA9, CD34, VEGFR1 and -3 and PDGRFα showed significant associations with progression-free survival (PFS and overall survival (OS. In multivariate Cox proportional hazards regression analyses high CA9 membrane staining and a response after 9 months were independent prognostic factors for longer OS. Frequently observed copy number loss and mutation of VHL gene lead to altered expression of VHL, HIF-1α, CA9, and VEGF. CONCLUSIONS: Immunoexpression of HIF-1α, CA9, Ki67, CD31, pVEGFR1, VEGFR1 and -2, pPDGFRα and -β in the primary tumors of metastatic ccRCC patients might support the

  15. Why do they not answer and do they really learn? A case study in analysing student response flows in introductory physics using an audience response system

    Science.gov (United States)

    Jääskeläinen, Markku; Lagerkvist, Andreas

    2017-07-01

    In this paper we investigate teaching with a classroom response system in introductory physics with emphasis on two issues. First, we discuss retention between question rounds and the reasons why students avoid answering the question a second time. A question with declining response rate was followed by a question addressing the student reasons for not answering. We find that there appear to be several reasons for the observed decline, and that the students need to be reminded. We argue that small drops are unimportant as the process appears to work despite the drops. Second, we discuss the dynamics of learning in a concept-sequence in electromagnetism, where a majority of the students, despite poor statistics in a first round, manage to answer a followup question correctly. In addition, we analyse the response times for both situations to connect with research on student reasoning on situations with misconception-like answers. From the combination of the answer flows and response time behaviours we find it plausible that conceptual learning occurred during the discussion phase.

  16. World Health Organization Quality-of-Life Scale (WHOQOL-BREF: Analyses Of Their Item Response Theory Properties Based On The Graded Responses Model

    Directory of Open Access Journals (Sweden)

    Shahrum Vahedi

    2010-11-01

    Full Text Available "nObjective: This study has used Item Response Theory (IRT to examine the psychometric properties of Health-Related Quality-of-Life. "nMethod: This investigation is a descriptive- analytic study. Subjects were 370 undergraduate students of nursing and midwifery who were selected from Tabriz University of Medical Sciences. All participants were asked to complete the Farsi version of WHOQOL-BREF. Samejima's graded response model was used for the analyses. "nResults: The results revealed that the discrimination parameters for all items in the four scales were low to moderate. The threshold parameters showed adequate representation of the relevant traits from low to the mean trait level. With the exception of 15, 18, 24 and 26 items, all other items showed low item information function values, and thus relatively high reliability from low trait levels to moderate levels. "nConclusions: The results of this study indicate that although there was general support for the psychometric properties of the WHOQOL-BREF from an IRT perspective, this measure can be further improved. IRT analyses provided useful measurement information and demonstrated to be a better methodological approach for enhancing our knowledge of the functionality of WHOQOL-BREF.

  17. World Health Organization Quality-of-Life Scale (WHOQOL-BREF): Analyses of Their Item Response Theory Properties Based on the Graded Responses Model

    Science.gov (United States)

    2010-01-01

    Objective This study has used Item Response Theory (IRT) to examine the psychometric properties of Health-Related Quality-of-Life. Method This investigation is a descriptive- analytic study. Subjects were 370 undergraduate students of nursing and midwifery who were selected from Tabriz University of Medical Sciences. All participants were asked to complete the Farsi version of WHOQOL-BREF. Samejima's graded response model was used for the analyses. Results The results revealed that the discrimination parameters for all items in the four scales were low to moderate. The threshold parameters showed adequate representation of the relevant traits from low to the mean trait level. With the exception of 15, 18, 24 and 26 items, all other items showed low item information function values, and thus relatively high reliability from low trait levels to moderate levels. Conclusions The results of this study indicate that although there was general support for the psychometric properties of the WHOQOL-BREF from an IRT perspective, this measure can be further improved. IRT analyses provided useful measurement information and demonstrated to be a better methodological approach for enhancing our knowledge of the functionality of WHOQOL-BREF. PMID:22952508

  18. Multiple damage identification and imaging in an aluminum plate using effective Lamb wave response automatic extraction technology

    Science.gov (United States)

    Ouyang, Qinghua; Zhou, Li; Liu, Xiaotong

    2016-04-01

    In order to identify multiple damage in the structure, a method of multiple damage identification and imaging based on the effective Lamb wave response automatic extraction algorithm is proposed. In this method, the detected key area in the structure is divided into a number of subregions, and then, the effective response signals including the structural damage information are automatically extracted from the entire Lamb wave responses which are received by the piezoelectric sensors. Further, the damage index values of every subregion based on the correlation coefficient are calculated using the effective response signals. Finally, the damage identification and imaging are performed using the reconstruction algorithm for probabilistic inspection of damage (RAPID) technique. The experimental research was conducted using an aluminum plate. The experimental results show that the method proposed in this research can quickly and effectively identify the single damage or multiple damage and image the damages clearly in detected area.

  19. Auditory Brainstem Response Wave Amplitude Characteristics as a Diagnostic Tool in Children with Speech Delay with Unknown Causes

    Directory of Open Access Journals (Sweden)

    Susan Abadi

    2016-09-01

    Full Text Available Speech delay with an unknown cause is a problem among children. This diagnosis is the last differential diagnosis after observing normal findings in routine hearing tests. The present study was undertaken to determine whether auditory brainstem responses to click stimuli are different between normally developing children and children suffering from delayed speech with unknown causes. In this cross-sectional study, we compared click auditory brainstem responses between 261 children who were clinically diagnosed with delayed speech with unknown causes based on normal routine auditory test findings and neurological examinations and had >12 months of speech delay (case group and 261 age- and sex-matched normally developing children (control group. Our results indicated that the case group exhibited significantly higher wave amplitude responses to click stimuli (waves I, III, and V than did the control group (P=0.001. These amplitudes were significantly reduced after 1 year (P=0.001; however, they were still significantly higher than those of the control group (P=0.001. The significant differences were seen regardless of the age and the sex of the participants. There were no statistically significant differences between the 2 groups considering the latency of waves I, III, and V. In conclusion, the higher amplitudes of waves I, III, and V, which were observed in the auditory brainstem responses to click stimuli among the patients with speech delay with unknown causes, might be used as a diagnostic tool to track patients’ improvement after treatment.

  20. Transcriptome and network analyses in Saccharomyces cerevisiae reveal that amphotericin B and lactoferrin synergy disrupt metal homeostasis and stress response

    Science.gov (United States)

    Pang, Chi Nam Ignatius; Lai, Yu-Wen; Campbell, Leona T.; Chen, Sharon C.-A.; Carter, Dee A.; Wilkins, Marc R.

    2017-01-01

    Invasive fungal infections are difficult to treat. The few available antifungal drugs have problems with toxicity or efficacy, and resistance is increasing. To overcome these challenges, existing therapies may be enhanced by synergistic combination with another agent. Previously, we found amphotericin B (AMB) and the iron chelator, lactoferrin (LF), were synergistic against a range of different fungal pathogens. This study investigates the mechanism of AMB-LF synergy, using RNA-seq and network analyses. AMB treatment resulted in increased expression of genes involved in iron homeostasis and ATP synthesis. Unexpectedly, AMB-LF treatment did not lead to increased expression of iron and zinc homeostasis genes. However, genes involved in adaptive response to zinc deficiency and oxidative stress had decreased expression. The clustering of co-expressed genes and network analysis revealed that many iron and zinc homeostasis genes are targets of transcription factors Aft1p and Zap1p. The aft1Δ and zap1Δ mutants were hypersensitive to AMB and H2O2, suggesting they are key regulators of the drug response. Mechanistically, AMB-LF synergy could involve AMB affecting the integrity of the cell wall and membrane, permitting LF to disrupt intracellular processes. We suggest that Zap1p- and Aft1p-binding molecules could be combined with existing antifungals to serve as synergistic treatments. PMID:28079179

  1. Shock Wave Response of Iron-based In Situ Metallic Glass Matrix Composites

    Science.gov (United States)

    Khanolkar, Gauri R.; Rauls, Michael B.; Kelly, James P.; Graeve, Olivia A.; Hodge, Andrea M.; Eliasson, Veronica

    2016-03-01

    The response of amorphous steels to shock wave compression has been explored for the first time. Further, the effect of partial devitrification on the shock response of bulk metallic glasses is examined by conducting experiments on two iron-based in situ metallic glass matrix composites, containing varying amounts of crystalline precipitates, both with initial composition Fe49.7Cr17.7Mn1.9Mo7.4W1.6B15.2C3.8Si2.4. The samples, designated SAM2X5-600 and SAM2X5-630, are X-ray amorphous and partially crystalline, respectively, due to differences in sintering parameters during sample preparation. Shock response is determined by making velocity measurements using interferometry techniques at the rear free surface of the samples, which have been subjected to impact from a high-velocity projectile launched from a powder gun. Experiments have yielded results indicating a Hugoniot Elastic Limit (HEL) to be 8.58 ± 0.53 GPa for SAM2X5-600 and 11.76 ± 1.26 GPa for SAM2X5-630. The latter HEL result is higher than elastic limits for any BMG reported in the literature thus far. SAM2X5-600 catastrophically loses post-yield strength whereas SAM2X5-630, while showing some strain-softening, retains strength beyond the HEL. The presence of crystallinity within the amorphous matrix is thus seen to significantly aid in strengthening the material as well as preserving material strength beyond yielding.

  2. Comparative proteomic and physiological analyses reveal the protective effect of exogenous calcium on the germinating soybean response to salt stress.

    Science.gov (United States)

    Yin, Yongqi; Yang, Runqiang; Han, Yongbin; Gu, Zhenxin

    2015-01-15

    suppressed under salt stress condition. According to previous studies, exogenous calcium counters the harmful effect of salt stress and increases the biomass and GABA content of germinating soybeans. Nevertheless, the precise molecular mechanism underlying the role of calcium in resistance to salt stress is still unknown. This paper is the first study employing comparative proteomic and physiological analyses to reveal the protective effect of exogenous calcium in the germinating soybean response to salt stress. Our study links the biological events with proteomic information and provides detailed peptide information on all identified proteins. The functions of those significantly changed proteins are also analyzed. The physiological and comparative proteomic analyses revealed the putative molecular mechanism of exogenous calcium treatment induced salt stress responses. The findings from this paper are beneficial to high GABA-rich germinating soybean biomass. Additionally, these findings also might be applicable to the genetic engineering of soybean plants to improve stress tolerance.

  3. Linear interaction analysis of a shock wave with a turbulent mixing; Analyse d'interaction lineaire d'un choc avec un melange turbulent

    Energy Technology Data Exchange (ETDEWEB)

    Griffond, J. [CEA Bruyeres-le-Chatel, 91 (France)

    2009-08-15

    The linear interaction analysis (LIA) is a theory aimed at predicting the evolution of a small perturbation field interaction with a shock wave. Despite its limited range of validity, it can be used for different applications among which 2 main kinds are of interest for us: the interaction of a shock wave with a perturbation of finite size (bubble, corrugated interface, etc.), and the interaction of shock wave with a statistically homogeneous turbulent mixture. The last configuration is of great interest for the development of turbulence models devoted to compressible mixing. (author)

  4. The Nonlinear Model of the Response of Airglow to Gravity Waves

    Institute of Scientific and Technical Information of China (English)

    J. Y. Xu; H. Gao; A.V. Mikhalev

    2005-01-01

    In this paper, we develope a timodependent, nonlinear, photochemical-dynamical 2-D model which is composed of 3 models: dynamical gravity wave model, middle atmospheric photochemical model, and airglow layer photochemical model. We use the model to study the effect of the gravity wave propagation on the airglow layer. The comparison between the effects of the different wavelength gravity wave on the airglow emission distributions is made. When the vertical wavelength of the gravity wave is close to or is shorter than the thickness of the airglow layer, the gravity wave can make complex structure of the airglow layer, such as the double and multi-peak structures of the airglow layer. However, the gravity wave that has long vertical wavelength can make large scale perturbation of the airglow emission distribution.

  5. Response of Charged Particles in a Storage Ring to Gravitational Waves

    Institute of Scientific and Technical Information of China (English)

    DONG Dong; HUANG Chao-Guang

    2003-01-01

    The influence of gravitational waves on the charged particles in a storage ring is studied. It shows thatthe gravitational waves might be directly detected by monitoring the motion of charged particles in a storage ring. Theangular velocity of the charged particles is continually adjustable by changing the initial energy of particles and thestrength of the magnetic field. This feature is very useful for finding the gravitational waves with different frequencies.

  6. Response of Charged Particles in a Storage Ring to Gravitational Waves

    Institute of Scientific and Technical Information of China (English)

    DONGDong; HUANGChao-Guang

    2003-01-01

    The influence of gravitational waves on the charged particles in a storage ring is studied. It shows that the gravitational waves might be directly detected by monitoring the motion of charged particles in a storage ring. The angular velocity of the charged particles is continually adjustable by changing the initial energy of particles and the strength of the magnetic field. This feature is very useful for finding the gravitational waves with different frequencies.

  7. Furcation Perforation: Periradicular Tissue Response to Biodentine as a Repair Material by Histopathologic and Indirect Immunofluorescence Analyses.

    Science.gov (United States)

    Silva, Lea Assed Bezerra; Pieroni, Karina Alessandra Michelão Grecca; Nelson-Filho, Paulo; Silva, Raquel Assed Bezerra; Hernandéz-Gatón, Patrícia; Lucisano, Marília Pacífico; Paula-Silva, Francisco Wanderley Garcia; de Queiroz, Alexandra Mussolino

    2017-07-01

    The purpose of this study was to evaluate the in vivo response of periradicular tissues after sealing of furcation perforations with Biodentine, mineral trioxide aggregate (MTA), and gutta-percha by means of histopathologic and indirect immunofluorescence analyses. Thirty teeth of 3 dogs were divided into 3 groups: Biodentine (n = 14 teeth), MTA (negative control, n = 10 teeth), and gutta-percha (positive control, n = 6 teeth). After endodontic treatment, perforations were made on the center of the pulp chamber floor and filled with the materials. After 120 days, the animals were killed, and blocks containing the teeth and periradicular tissues were processed histotechnically for histopathologic semiquantitative (new mineralized tissue formation and bone resorption at the perforation site) and quantitative (thickness and area of newly formed mineralized tissue and number of inflammatory cells) analyses and RUNX2 immunofluorescence assay. Data were analyzed by χ(2), Fisher exact test, Mann-Whitney test, one-way analysis of variance, Kruskal-Wallis test, and Dunn posttest (α = 0.05). MTA and Biodentine induced the formation of significantly more new mineralized tissue (P < .0001) than gutta-percha, which did not induce the formation of mineralized tissue in any case. Complete sealing of the perforations was more frequent with MTA, which formed mineralized tissue with greater thickness and area. Biodentine and MTA exhibited no bone resorption in the furcation region, fewer inflammatory cells, and greater RUNX2 immunostaining intensity than gutta-percha. Although MTA presented higher frequency of complete sealing and greater thickness and area of newly formed mineralized tissue, Biodentine also had good histopathologic results and can be considered as an adequate furcation perforation repair material. Copyright © 2017 American Association of Endodontists. Published by Elsevier Inc. All rights reserved.

  8. Geometrical optics response tensors and the transport of the wave energy density

    Energy Technology Data Exchange (ETDEWEB)

    Bornatici, M [INFM, Physics Department ' A. Volta' , University of Pavia, I-27100 Pavia (Italy); Maj, O [INFM, Physics Department, University of Milan, I-20133 Milan (Italy)

    2003-08-01

    Two forms of the transport equation for the wave energy density inherent in two (apparently diverse) formulations of geometrical optics (GO) are discussed on the basis of the relationships among the plane-wave dielectric tensor, the effective dielectric tensor and the effective conductivity tensor. For a generic space- and time-varying medium, a novel relationship between the dielectric tensor and the conductivity tensor is obtained whereupon the equivalence of the two GO formulations is established. The conditions for which either the wave action density or the wave energy density is conserved are discussed.

  9. Calculating Skempton constant of aquifer from volume strain and water level response to seismic waves at Changping seismic station

    Institute of Scientific and Technical Information of China (English)

    YAN Rui; CHEN Yong; GAO Fu-wang; HUANG Fu-qiong

    2008-01-01

    Based on linear poroelastic theory of ideal poroelastic media, we apply the mathematic expression between pore pressure and volume strain for well-aquifer system to analyzing the observed data of water level and volume strain changes aroused by Sumatra Ms8.7 (determined by China Seismic Networks Center) seismic waves at Changping, Beijing, station on December 26, 2004 from both time and frequency domain. The response coefficients of water level fluctuation to volume strain are also calculated when seismic waves were passing through confined aquifer. A method for estimating Skempton constant B is put forward, which provide an approach for understanding of the characteristics of aquifer.

  10. Nonlinear coupling of lower hybrid waves to the kinetic low-frequency plasma response in the auroral ionosphere

    Science.gov (United States)

    Sanbonmatsu, K. Y.; Goldman, M. V.; Newman, D. L.

    A hybrid kinetic-fluid model is developed which is relevant to lower hybrid spikelets observed in the topside auroral ionosphere [Vago et al., 1992; Eriksson et al., 1994]. In contrast to previous fluid models [Shapiro et al., 1995; Tam and Chang, 1995; Seyler, 1994; Shapiro et al., 1993] our linear low frequency plasma response is magnetized and kinetic. Fluid theory is used to incorporate the nonlinear wave coupling. Performing a linear stability analysis, we calculate the growth rate for the modulational instability, driven by a lower hybrid wave pump. We find that both the magnetic and kinetic effects inhibit the modulational instability.

  11. Analyses of Potential Predictive Markers and Response to Targeted Therapy in Patients with Advanced Clear-cell Renal Cell Carcinoma

    Institute of Scientific and Technical Information of China (English)

    Yan Song; Jing Huang; Ling Shan; Hong-Tu Zhang

    2015-01-01

    Background:Vascular endothelial growth factor-targeted agents are standard treatments in advanced clear-cell renal cell carcinoma (ccRCC),but biomarkers of activity are lacking.The aim of this study was to investigate the association of Von Hippel-Lindau (VHL) gene status,vascular endothelial growth factor receptor (VEGFR) or stem cell factor receptor (KIT) expression,and their relationships with characteristics and clinical outcome of advanced ccRCC.Methods:A total of 59 patients who received targeted treatment with sunitinib or pazopanib were evaluated for determination at Cancer Hospital and Institute,Chinese Academy of Medical Sciences between January 2010 and November 2012.Paraffin-embedded tumor samples were collected and status of the VHL gene and expression of VEGFR and KIT were determined by VHL sequence analysis and immunohistochemistry.Clinical-pathological features were collected and efficacy such as response rate and Median progression-free survival (PFS) and ovcrall survival (OS) were calculated and then compared based on expression status.The Chi-square test,the KaplanMeier method,and the Lon-rank test were used for statistical analyses.Results:Of 59 patients,objective responses were observed in 28 patients (47.5%).The median PFS was 13.8 months and median OS was 39.9 months.There was an improved PFS in patients with the following clinical features:Male gender,number of metastatic sites 2 or less,VEGFR-2 positive or KIT positive.Eleven patients (18.6%) had evidence of VHL mutation,with an objective response rate of 45.5%,which showed no difference with patients with no VHL mutation (47.9%).VHL mutation status did not correlate with either overall response rate (P =0.938) or PFS (P =0.277).The PFS was 17.6 months and 22.2 months in VEGFR-2 positive patients and KIT positive patients,respectively,which was significantly longer than that of VEGFR-2 or KIT negative patients (P =0.026 and P =0.043).Conclusion:VHL mutation status could not predict

  12. Analyses of Potential Predictive Markers and Response to Targeted Therapy in Patients with Advanced Clear-cell Renal Cell Carcinoma

    Directory of Open Access Journals (Sweden)

    Yan Song

    2015-01-01

    Full Text Available Background: Vascular endothelial growth factor-targeted agents are standard treatments in advanced clear-cell renal cell carcinoma (ccRCC, but biomarkers of activity are lacking. The aim of this study was to investigate the association of Von Hippel-Lindau (VHL gene status, vascular endothelial growth factor receptor (VEGFR or stem cell factor receptor (KIT expression, and their relationships with characteristics and clinical outcome of advanced ccRCC. Methods: A total of 59 patients who received targeted treatment with sunitinib or pazopanib were evaluated for determination at Cancer Hospital and Institute, Chinese Academy of Medical Sciences between January 2010 and November 2012. Paraffin-embedded tumor samples were collected and status of the VHL gene and expression of VEGFR and KIT were determined by VHL sequence analysis and immunohistochemistry. Clinical-pathological features were collected and efficacy such as response rate and Median progression-free survival (PFS and overall survival (OS were calculated and then compared based on expression status. The Chi-square test, the Kaplan-Meier method, and the Lon-rank test were used for statistical analyses. Results: Of 59 patients, objective responses were observed in 28 patients (47.5%. The median PFS was 13.8 months and median OS was 39.9 months. There was an improved PFS in patients with the following clinical features: Male gender, number of metastatic sites 2 or less, VEGFR-2 positive or KIT positive. Eleven patients (18.6% had evidence of VHL mutation, with an objective response rate of 45.5%, which showed no difference with patients with no VHL mutation (47.9%. VHL mutation status did not correlate with either overall response rate (P = 0.938 or PFS (P = 0.277. The PFS was 17.6 months and 22.2 months in VEGFR-2 positive patients and KIT positive patients, respectively, which was significantly longer than that of VEGFR-2 or KIT negative patients (P = 0.026 and P = 0.043. Conclusion

  13. Modelling of Anti-Tumour Immune Response: Immunocorrective Effect of Weak Centimetre Electromagnetic Waves

    Directory of Open Access Journals (Sweden)

    O. G. Isaeva

    2009-01-01

    Full Text Available We formulate the dynamical model for the anti-tumour immune response based on intercellular cytokine-mediated interactions with the interleukin-2 (IL-2 taken into account. The analysis shows that the expression level of tumour antigens on antigen presenting cells has a distinct influence on the tumour dynamics. At low antigen presentation, a progressive tumour growth takes place to the highest possible value. At high antigen presentation, there is a decrease in tumour size to some value when the dynamical equilibrium between the tumour and the immune system is reached. In the case of the medium antigen presentation, both these regimes can be realized depending on the initial tumour size and the condition of the immune system. A pronounced immunomodulating effect (the suppression of tumour growth and the normalization of IL-2 concentration is established by considering the influence of low-intensity electromagnetic microwaves as a parametric perturbation of the dynamical system. This finding is in qualitative agreement with the recent experimental results on immunocorrective effects of centimetre electromagnetic waves in tumour-bearing mice.

  14. Projected changes in African easterly wave intensity and track in response to greenhouse forcing.

    Science.gov (United States)

    Skinner, Christopher Bryan; Diffenbaugh, Noah S

    2014-05-13

    Synoptic-scale African easterly waves (AEWs) impact weather throughout the greater Atlantic basin. Over the African continent, AEWs are instrumental in initiating and organizing precipitation in the drought-vulnerable Sahel region. AEWs also serve as the precursors to the most intense Atlantic hurricanes, and contribute to the global transport of Saharan dust. Given the relevance of AEWs for the climate of the greater Atlantic basin, we investigate the response of AEWs to increasing greenhouse gas concentrations. Using an ensemble of general circulation models, we find a robust increase in the strength of the winds associated with AEWs along the Intertropical Front in West Africa by the late 21st century of the representative concentration pathway 8.5. AEW energy increases directly due to an increase in baroclinicity associated with an enhanced meridional temperature gradient between the Sahara and Guinea Coast. Further, the pattern of low-level warming supports AEW development by enhancing monsoon flow, resulting in greater convergence and uplift along the Intertropical Front. These changes in energetics result in robust increases in the occurrence of conditions that currently produce AEWs. Given relationships observed in the current climate, such changes in the location of AEW tracks and the magnitude of AEW winds carry implications for the relationship between AEWs and precipitation in the Sahel, the mobilization of Saharan dust, and the likelihood of cyclogenesis in the Atlantic. Our results therefore suggest that changes in AEW characteristics could play a critical role in shaping the response of Atlantic basin climate to future increases in greenhouse gas concentrations.

  15. Topographic effects on seismic response of long-span rigid-frame bridge under SV seismic wave

    Institute of Scientific and Technical Information of China (English)

    WANG Lei; ZHAO Cheng-gang; QU Tie-jun

    2008-01-01

    Seismic ground motions of two neighboring mountains and the free surface between them are calculated under the SV seismic waves with three different incident angles. The results are then taken as the inputs of multi-point seismic excitations for the foundation of a long-span bridge built over the valley in the analysis considering the inte-grated influence of traveling wave and topography. On the basis of a dynamic analytical method, a finite element model is created for the seismic responses of a four-span rigid-frame bridge of 440 m. The pier-top displacement and the pier-bottom internal force of the bridge are calculated. Then the results are compared with those considering traveling-wave effect only. The conclusions can serve as a seismic design reference for the structures located on the complex mountain topography.

  16. Topographic effects on seismic response of long-span rigid-frame bridge under SV seismic wave

    Science.gov (United States)

    Wang, Lei; Zhao, Cheng-Gang; Qu, Tie-Jun

    2008-05-01

    Seismic ground motions of two neighboring mountains and the free surface between them are calculated under the SV seismic waves with three different incident angles. The results are then taken as the inputs of multi-point seismic excitations for the foundation of a long-span bridge built over the valley in the analysis considering the integrated influence of traveling wave and topography. On the basis of a dynamic analytical method, a finite element model is created for the seismic responses of a four-span rigid-frame bridge of 440 m. The pier-top displacement and the pier-bottom internal force of the bridge are calculated. Then the results are compared with those considering traveling-wave effect only. The conclusions can serve as a seismic design reference for the structures located on the complex mountain topography.

  17. Numerical analysis of dynamic response of jacket structures subject to slamming forces by breaking waves

    Directory of Open Access Journals (Sweden)

    Chanjo Woo

    2017-07-01

    Full Text Available The present study numerically analyzed the dynamic behavior of 3D framed structures subject to impulsive slamming forces by violent breaking waves. The structures were modeled using multiple lumped masses for the vertical projections of each member, and the slamming forces from the breaking waves were concentrated on these lumped masses. A numerical algorithm was developed to properly incorporate the slamming forces into a dynamic analysis to numerically determine the structural responses. Then, the validity of the numerical analysis was verified using the results of an existing hydraulic experiment. The numerical and experimental results for various model structures were generally in good agreement. The uncertainties concerning the properties of the breaking waves used in the verification are also discussed here.

  18. Enzyme Activity Dynamics in Response to Climate Change: 2011 Drought-Heat Wave

    Science.gov (United States)

    Extreme weather events such as severe droughts and heat waves may have permanent consequences on soil quality and functioning in agroecosystems. The Southern High Plains (SHP) region of Texas, U.S., a large cotton producing area, experienced a historically extreme drought and heat wave during 2011,...

  19. Automated calculation of anharmonic vibrational contributions to first hyperpolarizabilities: quadratic response functions from vibrational configuration interaction wave functions.

    Science.gov (United States)

    Hansen, Mikkel Bo; Christiansen, Ove; Hättig, Christof

    2009-10-21

    Quadratic response functions are derived and implemented for a vibrational configuration interaction state. Combined electronic and vibrational quadratic response functions are derived using Born-Oppenheimer vibronic product wave functions. Computational tractable expressions are derived for determining the total quadratic response contribution as a sum of contributions involving both electronic and vibrational linear and quadratic response functions. In the general frequency-dependent case this includes a new and more troublesome type of electronic linear response function. Pilot calculations for the FH, H(2)O, CH(2)O, and pyrrole molecules demonstrate the importance of vibrational contributions for accurate comparison to experiment and that the vibrational contributions in some cases can be very large. The calculation of transition properties between vibrational states is combined with sum-over-states expressions for analysis purposes. On the basis of this some simple analysis methods are suggested. Also, a preliminary study of the effect of finite lifetimes on quadratic response functions is presented.

  20. Dynamic Excitation of Monopiles by Steep and Breaking Waves: Experimental and Numerical Study

    DEFF Research Database (Denmark)

    Bredmose, Henrik; Slabiak, Peter; Sahlberg-Nielsen, Lasse;

    2013-01-01

    . The measured data for structural acceleration is analysed with respect to individual wave parameters. It is found that the largest accelerations occur for breaking waves. The measured wave field and structural response are reproduced numerically with a fully nonlinear potential flow solver for the undisturbed...... wave kinematics, combined with a finite element model with Morison-based forcing. A good overall reproduction of the wave field and structural response is achieved for two selected episodes. For some of the waves, however, the numerical response magnitude does not match the observed excitations...

  1. Letter to the editor: The ionospheric response during an interval of Pc5 ULF wave activity

    Directory of Open Access Journals (Sweden)

    M. Lester

    Full Text Available A preliminary analysis of Pc5, ULF wave activity observed with the IMAGE magnetometer array and the EISCAT UHF radar in the post midnight sector indicates that such waves can be caused by the modulation of the ionospheric conductivity as well as the wave electric field. An observed Pc5 pulsation is divided into three separate intervals based upon the EISCAT data. In the first and third, the Pc5 waves are observed only in the measured electron density between 90 and 112 km and maxima in the electron density at these altitudes are attributed to pulsed precipitation of electrons with energies up to 40 keV which result in the height integrated Hall conductivity being pulsed between 10 and 50 S. In the second interval, the Pc5 wave is observed in the F-region ion temperature, electron density and electron temperature but not in the D and E region electron densities. The analysis suggests that the wave during this interval is a coupled Alfven and compressional mode.

    Key words: Ionosphere (electric fields and currents - Magnetospheric physics (magnetosphere-ionosphere interaction; MHD waves and instabilities

  2. Nuclear electromagnetic moments of the ground states of /sup 148/Pm and /sup 210/Bi calculated with phenomenological wave functions derived from analyses of. beta. -decay experiments

    Energy Technology Data Exchange (ETDEWEB)

    Rosso, O.A.; Szybisz, L.

    1983-12-01

    The magnetic dipole and electric quadrupole moments of the ground states of /sup 148/Pm and /sup 210/Bi are evaluated with phenomenological wave functions derived from ..beta..-decay studies published in previous works. It is found that these wave functions account satisfactorily for the experimental data of both nuclear moments of the /sup 210/Bi ground state. In the case of /sup 148/Pm, while the calculated value of the electric quadrupole moment is not inconsistent with the experimental data, a strong disagreement between theory and experiment is found for the magnetic dipole moment. We attribute this failure to the use of a too small configuration space for the expansion of the nuclear wave function of /sup 148/Pm.

  3. Nuclear electromagnetic moments of the ground states of148Pm and210Bi calculated with phenomenological wave functions derived from analyses of β-decay experiments

    Science.gov (United States)

    Rosso, O. A.; Szybisz, L.

    1983-10-01

    The magnetic dipole and electric quadrupole moments of the ground states of148Pm and210Bi are evaluated with phenomenological wave functions derived from β-decay studies published in previous works. It is found that these wave functions account satisfactorily for the experimental data of both nuclear moments of the210Bi ground state. In the case of148Pm, while the calculated value of the electric quadrupole moment is not inconsistent with the experimental data, a strong disagreement between theory and experiment is found for the magnetic dipole moment. We attribute this failure to the use of a too small configuration space for the expansion of the nuclear wave function of148Pm.

  4. SPIRAL DENSITY WAVES IN M81. II. HYDRODYNAMIC SIMULATIONS OF THE GAS RESPONSE TO STELLAR SPIRAL DENSITY WAVES

    Energy Technology Data Exchange (ETDEWEB)

    Wang, Hsiang-Hsu; Lee, Wing-Kit; Taam, Ronald E.; Feng, Chien-Chang; Lin, Lien-Hsuan, E-mail: hhwang@asiaa.sinica.edu.tw [Institute of Astronomy and Astrophysics, Academia Sinica, P.O. Box 23-141, Taipei 10617, Taiwan, ROC (China)

    2015-02-20

    The gas response to the underlying stellar spirals is explored for M81 using unmagnetized hydrodynamic simulations. Constrained within the uncertainty of observations, 18 simulations are carried out to study the effects of self-gravity and to cover the parameter space comprising three different sound speeds and three different arm strengths. The results are confronted with the data observed at wavelengths of 8 μm and 21 cm. In the outer disk, the ring-like structure observed in the 8 μm image is consistent with the response of cold neutral medium with an effective sound speed 7 km s{sup –1}. For the inner disk, the presence of spiral shocks can be understood as a result of 4:1 resonances associated with the warm neutral medium with an effective sound speed 19 km s{sup –1}. Simulations with a single effective sound speed alone cannot simultaneously explain the structures in the outer and inner disks. Instead this justifies the coexistence of cold and warm neutral media in M81. The anomalously high streaming motions observed in the northeast arm and the outward shifted turning points in the iso-velocity contours seen along the southwest arm are interpreted as signatures of interactions with companion galaxies. The level of simulated streaming motions narrows down the uncertainty of the observed arm strength toward larger amplitudes.

  5. Gene expression analyses implicate an alternative splicing program in regulating contractile gene expression and serum response factor activity in mice.

    Directory of Open Access Journals (Sweden)

    Twishasri Dasgupta

    Full Text Available Members of the CUG-BP, Elav-like family (CELF regulate alternative splicing in the heart. In MHC-CELFΔ transgenic mice, CELF splicing activity is inhibited postnatally in heart muscle via expression of a nuclear dominant negative CELF protein under an α-myosin heavy chain promoter. MHC-CELFΔ mice develop dilated cardiomyopathy characterized by alternative splicing defects, enlarged hearts, and severe contractile dysfunction. In this study, gene expression profiles in the hearts of wild type, high- and low-expressing lines of MHC-CELFΔ mice were compared using microarrays. Gene ontology and pathway analyses identified contraction and calcium signaling as the most affected processes. Network analysis revealed that the serum response factor (SRF network is highly affected. Downstream targets of SRF were up-regulated in MHC-CELFΔ mice compared to the wild type, suggesting an increase in SRF activity. Although SRF levels remained unchanged, known inhibitors of SRF activity were down-regulated. Conversely, we found that these inhibitors are up-regulated and downstream SRF targets are down-regulated in the hearts of MCKCUG-BP1 mice, which mildly over-express CELF1 in heart and skeletal muscle. This suggests that changes in SRF activity are a consequence of changes in CELF-mediated regulation rather than a secondary result of compensatory pathways in heart failure. In MHC-CELFΔ males, where the phenotype is only partially penetrant, both alternative splicing changes and down-regulation of inhibitors of SRF correlate with the development of cardiomyopathy. Together, these results strongly support a role for CELF-mediated alternative splicing in the regulation of contractile gene expression, achieved in part through modulating the activity of SRF, a key cardiac transcription factor.

  6. Contrasting responses of urban and rural surface energy budgets to heat waves explain synergies between urban heat islands and heat waves

    Science.gov (United States)

    Li, Dan; Sun, Ting; Liu, Maofeng; Yang, Long; Wang, Linlin; Gao, Zhiqiu

    2015-05-01

    Heat waves (HWs) are projected to become more frequent and last longer over most land areas in the late 21st century, which raises serious public health concerns. Urban residents face higher health risks due to synergies between HWs and urban heat islands (UHIs) (i.e., UHIs are higher under HW conditions). However, the responses of urban and rural surface energy budgets to HWs are still largely unknown. This study analyzes observations from two flux towers in Beijing, China and reveals significant differences between the responses of urban and rural (cropland) ecosystems to HWs. It is found that UHIs increase significantly during HWs, especially during the nighttime, implying synergies between HWs and UHIs. Results indicate that the urban site receives more incoming shortwave radiation and longwave radiation due to HWs as compared to the rural site, resulting in a larger radiative energy input into the urban surface energy budget. Changes in turbulent heat fluxes also diverge strongly for the urban site and the rural site: latent heat fluxes increase more significantly at the rural site due to abundant available water, while sensible heat fluxes and possibly heat storage increase more at the urban site. These comparisons suggest that the contrasting responses of urban and rural surface energy budgets to HWs are responsible for the synergies between HWs and UHIs. As a result, urban mitigation and adaption strategies such as the use of green roofs and white roofs are needed in order to mitigate the impact of these synergies.

  7. Simulation of response of sodium layer to the propagation of gravity wave

    Institute of Scientific and Technical Information of China (English)

    XU Jiyao

    2004-01-01

    A time-dependent two-dimensional photochemical-dynamical coupling gravity wave model of sodium layer is developed, which combines the sodium photochemical theory, a time-dependent two-dimensional atmospheric photochemical model, a two-dimensional gravity wave model, and the International Reference Ionosphere model (IRI-95)with the diabatic process induced by photochemical reactions and the transport of chemical species by gravity waves included. The pseudospectral method is used in the horizontal direction, the finite difference approximations are used in vertical direction z and time t. And FICE method is used to solve the model. The simulation results indicate that intense perturbations of the sodium layer can be induced by the propagation of gravity waves. The results are consistent with the observations.

  8. Comparison of Blood Pressure and Thermal Responses in Rats Exposed to Millimeter Wave Energy or Environmental Heat

    Science.gov (United States)

    2005-12-22

    nerve injury rats exhibit millimeter wave length: potential occupational safety issues relating to surface thermal hyperalgesia on an automated...May 2006 1 Journal Article I Aug 2005 - May 2006 4. TITLE AND SUBTITLE 5a. CONTRACT NUMBER Comparison of Blood Pressure and Thermal Responses in Rats...Z39.18 5-1 •ATEThENTA SHOCK, Vol. 25, No. 6, pp. 625-632, 2006 Approved for Public Release Distribution Unlimited COMPARISON OF BLOOD PRESSURE AND THERMAL

  9. Nondeterministic wave-based methods for low- and mid-frequency response analysis of acoustic field with limited information

    Science.gov (United States)

    Xia, Baizhan; Yin, Hui; Yu, Dejie

    2017-02-01

    The response of the acoustic field, especially for the mid-frequency response, is very sensitive to uncertainties rising from manufacturing/construction tolerances, aggressive environmental factors and unpredictable excitations. To quantify these uncertainties with limited information effectively, two nondeterministic models (the interval model and the hybrid probability-interval model) are introduced. And then, two corresponding nondeterministic numerical methods are developed for the low- and mid-frequency response analysis of the acoustic field under these two nondeterministic models. The first one is the interval perturbation wave-based method (IPWBM) which is proposed to predict the maximal values of the low- and mid-frequency responses of the acoustic field under the interval model. The second one is the hybrid perturbation wave-based method (HPWBM) which is proposed to predict the maximal values of expectations and standard variances of the low- and mid-frequency responses of the acoustic field under the hybrid probability-interval model. The effectiveness and efficiency of the proposed nondeterministic numerical methods for the low- and mid-frequency response analysis of the acoustic field under the interval model and the hybrid probability-interval model are investigated by a numerical example.

  10. On Wave-Ice Interaction in the Arctic Marginal Ice Zone: Dispersion, Attenuation, and Ice Response

    Science.gov (United States)

    2016-06-01

    for forecasting waves in the Arctic and thus many simplifications are necessary. An anecdote, related by Zubov via an earlier publication by...Naval Research Laboratory Stennis Space Center, MS 39529-5004 NRL/MR/7320--16-9676 Approved for public release; distribution is unlimited. On Wave...To) Standard Form 298 (Rev. 8-98) Prescribed by ANSI Std. Z39.18 Public reporting burden for this collection of information is estimated to average 1

  11. All-Atom Molecular-Level Computational Analyses of Polyurea/Fused-Silica Interfacial Decohesion Caused by Impinging Tensile Stress-Waves

    Science.gov (United States)

    2014-01-01

    Interfacial decohesion, Reactive forcefields Paper type Research paper International Journal of Structural Integrity Vol. 5 No. 4, 2014 pp. 339-367 © Emerald ...interaction was conducted to provide additional insight into the outcome of the stress-wave/interface interactions. 4. Results and discussion The main emphasis

  12. Fully Coupled Three-Dimensional Dynamic Response of a TLP Floating Wind Turbine in Waves and Wind

    DEFF Research Database (Denmark)

    Ramachandran, Gireesh Kumar V.R.; Bredmose, Henrik; Sørensen, Jens Nørkær

    2013-01-01

    A dynamic model for a tension-leg platform (TLP) floating offshore wind turbine is proposed. The model includes threedimensional wind and wave loads and the associated structural response. The total system is formulated using 17 degrees of freedom (DOF), 6 for the platform motions and 11 for the ...... and discussed. As a next step (which is not presented here), the dynamic model for the substructure is therefore being coupled to an advanced aero-elastic code Flex5, Øye (1996), which has a higher number of DOFs and a controller module.......A dynamic model for a tension-leg platform (TLP) floating offshore wind turbine is proposed. The model includes threedimensional wind and wave loads and the associated structural response. The total system is formulated using 17 degrees of freedom (DOF), 6 for the platform motions and 11......, including Glauert correction for high values of axial induction factor, dynamic stall, dynamic wake and dynamic yaw. The aerodynamic model takes into account the wind shear and turbulence effects. For a representative geographic location, platform responses are obtained for a set of wind and wave climatic...

  13. Ecosystem Engineering by Plants on Wave-Exposed Intertidal Flats Is Governed by Relationships between Effect and Response Traits.

    Directory of Open Access Journals (Sweden)

    Maike Heuner

    Full Text Available In hydrodynamically stressful environments, some species--known as ecosystem engineers--are able to modify the environment for their own benefit. Little is known however, about the interaction between functional plant traits and ecosystem engineering. We studied the responses of Scirpus tabernaemontani and Scirpus maritimus to wave impact in full-scale flume experiments. Stem density and biomass were used to predict the ecosystem engineering effect of wave attenuation. Also the drag force on plants, their bending angle after wave impact and the stem biomechanical properties were quantified as both responses of stress experienced and effects on ecosystem engineering. We analyzed lignin, cellulose, and silica contents as traits likely effecting stress resistance (avoidance, tolerance. Stem density and biomass were strong predictors for wave attenuation, S. maritimus showing a higher effect than S. tabernaemontani. The drag force and drag force per wet frontal area both differed significantly between the species at shallow water depths (20 cm. At greater depths (35 cm, drag forces and bending angles were significantly higher for S. maritimus than for S. tabernaemontani. However, they do not differ in drag force per wet frontal area due to the larger plant surface of S. maritimus. Stem resistance to breaking and stem flexibility were significantly higher in S. tabernaemontani, having a higher cellulose concentration and a larger cross-section in its basal stem parts. S. maritimus had clearly more lignin and silica contents in the basal stem parts than S. tabernaemontani. We concluded that the effect of biomass seems more relevant for the engineering effect of emergent macrophytes with leaves than species morphology: S. tabernaemontani has avoiding traits with minor effects on wave attenuation; S. maritimus has tolerating traits with larger effects. This implies that ecosystem engineering effects are directly linked with traits affecting species

  14. Maslov shear-waveforms in highly anisotropic shales and implications for shear-wave splitting analyses; Formes d`onde transversales de Maslov dans les argiles fortement anisotropes et implications dans les analyses de birefringence des ondes transversales

    Energy Technology Data Exchange (ETDEWEB)

    Caddick, J. [Leeds Univ. (United Kingdom). Dept. of Earth Sciences; Kendall, J.M.; Raymer, D.G. [Western Geophysical, Middlesex (United Kingdom). Dept. of Earth Sciences

    1998-09-01

    Shales are the most common sedimentary rocks in hydrocarbon environments often forming the source rock and trapping rock for a reservoir. Due to the platy nature of the constituent grains, shales are commonly anisotropic. In this paper we calculate seismic waveforms for highly anisotropic shales using Maslow asymptotic theory (MAT). This theory is an extension of classical ray theory which provides valid waveforms in regions of caustics (wavefront folding) where ray theory amplitudes are unstable. Asymptotic ray theory (ART) is based on the Fermat or geometrical ray which connects the source and receiver. In contrast, the Maslov solution integrates the contributions from neighbouring non-Fermat rays. Ray-paths, travel-times, amplitudes and synthetic seismograms are presented for three highly anisotropic shales using a very simple 1D model comprised of an anisotropic shale overlying an isotropic shale. The ART waveforms fail to account for complex waveform effects due to triplications. In comparison, the MAT waveforms predict nonsingular amplitudes at wavefront cusps and it predicts the diffracted signals from these cusps. A Maslov solution which integrates ray contributions over a single slowness component will break down when rays focus in 3D (at a point rather than along a line). One of the tested shales shows such a point caustic and integration over 2 slowness components is required to remove the amplitude singularity. Finally, we examine the effects of wavefront triplications on Alford rotations which are used to estimate shear-wave splitting. In such cases, the rotation successfully finds the fast shear-wave polarization, but it can be unreliable in its estimate of the time separation. (authors) 21 refs.

  15. Heave-roll-pitch coupled nonlinear internal resonance response of a spar platform considering wave and vortex exciting loads

    Science.gov (United States)

    Li, Wei; Tang, Yougang; Liu, Liqin; Liu, Shuxiao; Cai, Runbo

    2017-04-01

    Many studies have been done on the heave-pitch unstable coupling response for a spar platform by a 2-DOF model. In fact, in addition to the heave and pitch which are in one plane, the nonlinear unstable motion will also occur in roll. From the results of the experiments, the unstable roll motion plays a dominant role in the motion of a spar platform which is much stronger than that of pitch. The objective of this paper is to study 3-DOF coupling response performance of spar platform under wave and vortex-induced force. The nonlinear coupled equations in heave, roll and pitch are established by considering time-varying wet surface and coupling. The first order steady-state response is solved by multi-scales method when the incident wave frequency approaches the heave natural frequency. Numerical integration of the motion equations has been performed to verify the first-order perturbation solution. The results are confirmed by model test. There is a saturation phenomenon associated with heave mode in 3-DOF systems and all extra energy is transferred to roll and pitch. It is observed that sub-harmonic response occurs in roll and pitch when the wave force exceeds a certain value. The energy distribution in roll and pitch is determined by the initial value and damping characteristics of roll and pitch. The energy transfers from heave to pitch and then transfers from pitch to roll. Due to the influence of the low-frequency vortex-excited force, the response of roll is more complicated than that of pitch.

  16. Inverse least-squares modeling of vapor descriptors using polymer-coated surface acoustic wave sensor array responses.

    Science.gov (United States)

    Grate, J W; Patrash, S J; Kaganovet, S N; Abraham, M H; Wise, B M; Gallagher, N B

    2001-11-01

    In previous work, it was shown that, in principle, vapor descriptors could be derived from the responses of an array of polymer-coated acoustic wave devices. This new chemometric classification approach was based on polymer/vapor interactions following the well-established linear solvation energy relationships (LSERs) and the surface acoustic wave (SAW) transducers being mass sensitive. Mathematical derivations were included and were supported by simulations. In this work, an experimental data set of polymer-coated SAW vapor sensors is investigated. The data set includes 20 diverse polymers tested against 18 diverse organic vapors. It is shown that interfacial adsorption can influence the response behavior of sensors with nonpolar polymers in response to hydrogen-bonding vapors; however, in general, most sensor responses are related to vapor interactions with the polymers. It is also shown that polymer-coated SAW sensor responses can be empirically modeled with LSERs, deriving an LSER for each individual sensor based on its responses to the 18 vapors. Inverse least-squares methods are used to develop models that correlate and predict vapor descriptors from sensor array responses. Successful correlations can be developed by multiple linear regression (MLR), principal components regression (PCR), and partial least-squares (PLS) regression. MLR yields the best fits to the training data, however cross-validation shows that prediction of vapor descriptors for vapors not in the training set is significantly more successful using PCR or PLS. In addition, the optimal dimension of the PCR and PLS models supports the dimensionality of the LSER formulation and SAW response models.

  17. Piezoelectric responses of brittle rock mass containing quartz to static stress and exploding stress wave respectively

    Institute of Scientific and Technical Information of China (English)

    WAN Guo-xiang; LI Xi-bing; HONG Liang

    2008-01-01

    The electromagnetic emission (EME) induced from the rock containing piezoelectric materials was investigated under both static stress and exploding stress wave in the view of piezoelectric effect. The results show that the intensity of the EME induced from the rock under static stress increases with increasing stress level and loading rate; the relationship between the amplitude of theme from the rock under different modes of stress wave and elastic parameters and propagation distance was presented. The intensity of the EME relates not only to the strength and elastic moduli of rock masses, but also to the initial damage of the rock. The intensity of EME induced by stress wave reaches the highest at the explosion-center and attenuates with the propagation distance. The intensity of EME increases with increasing the elastic modulus and decreases with increasing initial damage. The results are in good agreement with the experimental results.

  18. Wave kinematics and response of slender offshore structures. Vol 1: Summary report

    Energy Technology Data Exchange (ETDEWEB)

    Ottesen Hansen, N.E.

    1999-08-01

    Full-scale vortex-induced vibrations (VIV) have been measured on an instrumented pipe placed vertically in the crest zone of high and steep waves. The Reynolds numbers were in the range 10{sup 5} to 10{sup 6}. It was found that the vortex-induced vibrations in the wave motion were generated within a reduced velocity range of 4 and 8. The vibrations grew intermittently with the passing waves. The vibrations took place in 2-3 modes simultaneously. One mode, however, dominated over the other. The growth of the simulated VIV using a modal analysis, were consistent with a basic correlation length of 3 diameters for a stationary pipe with a linear growth of the correlation length of 10 diameters for each 0.1 diameter amplitude. (LN)

  19. A special form of electrodynamical response to a gravitational wave: outgoing and imploding photon fluxes

    Institute of Scientific and Technical Information of China (English)

    李芳昱; 苏荀; 龙炳蔚; 唐孟希

    2002-01-01

    We have investigated the interaction of an electromagnetic (EM) wave with a standing gravitational wave (GW)in an external static magnetic field, and obtained concrete forms of first-order perturbative EM energy fluxes. Unlikethe propagating properties of the "left-circular" and "right-circular" waves of the tangential perturbative energy fluxesaround the symmetricalaxis, the radial perturbative energy fluxes are expressed as the outgoing and imploding wavesto the symmetrical axis.We also examine several physical examples and show that this effect can produce very smallbut nonvanishing radial perturbative photon fluxes. This may be useful for EM detection of the high-frequency relicGWs of the GHz region in quintessential inflationary models.

  20. Numerical response analysis of a large mat-type floating structure in regular waves; Matogata choogata futai kozobutsu no haro oto kaiseki

    Energy Technology Data Exchange (ETDEWEB)

    Yasuzawa, Y.; Kagawa, K.; Kitabayashi, K. [Kyushu University, Fukuoka (Japan); Kawano, D. [Mitsubishi Heavy Industries, Ltd., Tokyo (Japan)

    1997-08-01

    The theory and formulation for the numerical response analysis of a large floating structure in regular waves were given. This paper also reports the comparison between the experiment in the Shipping Research Institute in the Minitry of Transport and the result calculated using numerical analytic codes in this study. The effect of the bending rigidity of a floating structure and the wave direction on the dynamic response of a structure was examined by numerical calculation. When the ratio of structure length and incident wavelength (L/{lambda}) is lower, the response amplitude on the transmission side becomes higher in a wave-based response. The hydrodynamic elasticity exerts a dominant influence when L/{lambda} becomes higher. For incident oblique waves, the maximum response does not necessarily appear on the incidence side. Moreover, the response distribution is also complicated. For example, the portion where any flexible amplitude hardly appears exists. A long structure response can be predicted from a short structure response to some degree. They differ in response properties when the ridigity based on the similarity rule largely differs, irrespective of the same L/{lambda}. For higher L/{lambda}, the wave response can be easily predicted when the diffrection force is replaced by the concentrated exciting force on the incidence side. 13 refs., 14 figs., 3 tabs.

  1. Beach Response to Wave Energy Converter Farms Acting as Coastal Defence

    DEFF Research Database (Denmark)

    Mendoza, Edgar; Silva, Rodolfo; Zanuttigh, Barbara

    2014-01-01

    beach maintenance and coastal safety. This may be an opportunity for the multi-purpose use of Wave Energy Converters (WECs) if the foreseen increase of energy demand in coastal areas is also considered. In this paper a group of WECs based on different operating concepts is numerically tested in front...... against new experimental results. The wave field is then used as input for the analytical calculation of the long-shore sediment transport and the coastline trend is estimated by applying the continuity of sediment equation. The characteristics of the selected numerical models give this work a first...

  2. Analytical Models for the Response of the Double-Bottom Structure to Underwater Explosion Based on the Wave Motion Theory

    Directory of Open Access Journals (Sweden)

    Yingyu Chen

    2016-01-01

    Full Text Available The aim of this paper is to apply the elastic wave motion theory and the classical one-dimensional cavitation theory to analyze the response of a typical double-bottom structure subjected to underwater blast. The section-varying bar theory and the general acoustic impedance are introduced to get the simplified analytical models. The double-bottom structure is idealized by the basic unit of three substructures which include the simple panel, the panel with stiffener (T-shaped, and the panel associated with girder (I-shaped. According to the simplified models, the analytical models for the corresponding substructures are set up. By taking the cavitation effect into account, the process of fluid-structure interaction can be thoroughly understood, as well as the stress wave propagation. Good agreement between the analytical solution and the finite element prediction is achieved. On the other hand, the Taylor predictions for the panel associated with girder (I-shaped including the effects of cavitation are invalid, indicating a potential field for the analytical method. The validated analytical models are used to determine the sensitivity of structure response to dimensionless geometric parameters α-k, β-k, and γ-k. Based on the dynamic response of the substructures, we establish the approximate analytical models which are able to predict the response of double-bottom structure to underwater explosion.

  3. Monocular and binocular steady-state flicker VEPs: frequency-response functions to sinusoidal and square-wave luminance modulation.

    Science.gov (United States)

    Nicol, David S; Hamilton, Ruth; Shahani, Uma; McCulloch, Daphne L

    2011-02-01

    Steady-state VEPs to full-field flicker (FFF) using sinusoidally modulated light were compared with those elicited by square-wave modulated light across a wide range of stimulus frequencies with monocular and binocular FFF stimulation. Binocular and monocular VEPs were elicited in 12 adult volunteers to FFF with two modes of temporal modulation: sinusoidal or square-wave (abrupt onset and offset, 50% duty cycle) at ten temporal frequencies ranging from 2.83 to 58.8 Hz. All stimuli had a mean luminance of 100 cd/m(2) with an 80% modulation depth (20-180 cd/m(2)). Response magnitudes at the stimulus frequency (F1) and at the double and triple harmonics (F2 and F3) were compared. For both sinusoidal and square-wave flicker, the FFF-VEP magnitudes at F1 were maximal for 7.52 Hz flicker. F2 was maximal for 5.29 Hz flicker, and F3 magnitudes are largest for flicker stimulation from 3.75 to 7.52 Hz. Square-wave flicker produced significantly larger F1 and F2 magnitudes for slow flicker rates (up to 5.29 Hz for F1; at 2.83 and 3.75 Hz for F2). The F3 magnitudes were larger overall for square-wave flicker. Binocular FFF-VEP magnitudes are larger than those of monocular FFF-VEPs, and the amount of this binocular enhancement is not dependant on the mode of flicker stimulation (mean binocular: monocular ratio 1.41, 95% CI: 1.2-1.6). Binocular enhancement of F1 for 21.3 Hz flicker was increased to a factor of 2.5 (95% CI: 1.8-3.5). In the healthy adult visual system, FFF-VEP magnitudes can be characterized by the frequency-response functions of F1, F2 and F3. Low-frequency roll-off in the FFF-VEP magnitudes is greater for sinusoidal flicker than for square-wave flicker for rates ≤ 5.29 Hz; magnitudes for higher-frequency flicker are similar for the two types of flicker. Binocular FFF-VEPs are larger overall than those recorded monocularly, and this binocular summation is enhanced at 21.3 Hz in the mid-frequency range.

  4. Observations of wave-induced pore pressure gradients and bed level response on a surf zone sandbar

    Science.gov (United States)

    Anderson, Dylan; Cox, Dan; Mieras, Ryan; Puleo, Jack A.; Hsu, Tian-Jian

    2017-06-01

    Horizontal and vertical pressure gradients may be important physical mechanisms contributing to onshore sediment transport beneath steep, near-breaking waves in the surf zone. A barred beach was constructed in a large-scale laboratory wave flume with a fixed profile containing a mobile sediment layer on the crest of the sandbar. Horizontal and vertical pore pressure gradients were obtained by finite differences of measurements from an array of pressure transducers buried within the upper several centimeters of the bed. Colocated observations of erosion depth were made during asymmetric wave trials with wave heights between 0.10 and 0.98 m, consistently resulting in onshore sheet flow sediment transport. The pore pressure gradient vector within the bed exhibited temporal rotations during each wave cycle, directed predominantly upward under the trough and then rapidly rotating onshore and downward as the wavefront passed. The magnitude of the pore pressure gradient during each phase of rotation was correlated with local wave steepness and relative depth. Momentary bed failures as deep as 20 grain diameters were coincident with sharp increases in the onshore-directed pore pressure gradients, but occurred at horizontal pressure gradients less than theoretical critical values for initiation of the motion for compact beds. An expression combining the effects of both horizontal and vertical pore pressure gradients with bed shear stress and soil stability is used to determine that failure of the bed is initiated at nonnegligible values of both forces.Plain Language SummaryThe pressure gradient present within the seabed beneath breaking waves may be an important physical mechanism transporting sediment. A large-scale laboratory was used to replicate realistic surfzone conditions in controlled tests, allowing for horizontal and vertical pressure gradient magnitudes and the resulting sediment bed response to be observed with precise instruments. Contrary to previous studies

  5. The effect of local corticosteroid injection on F-wave conduction velocity and sympathetic skin response in carpal tunnel syndrome.

    Science.gov (United States)

    Deniz, Orhan; Aygül, Recep; Kotan, Dilcan; Ozdemir, Gökhan; Odabaş, Faruk Omer; Kaya, M Dursun; Ulvi, Hızır

    2012-05-01

    The aim of this study was to evaluate the efficacy of steroid injection for the treatment of the carpal tunnel syndrome (CTS), with F-wave parameters and sympathetic skin response (SSR). Seventeen hands of 10 women patients were treated with local steroid injection with 2-month follow-up. All patients underwent single injection into the carpal tunnel. Response to injection was measured nerve conduction studies (NCSs), median nerve F waves, and SSR before and after treatment. To determine the normal values, 42 hands of 21 healthy women were also studied. There was a significant improvement of sensory and motor nerve conduction values when compared to baseline values (P sensory distal latency and the sensory latency differences between the median and the ulnar nerve were improved 35 and 65%, respectively. The maximum, mean F-wave amplitudes and chronodispersion showed a slight improvement with respect to baseline values and controls, but statistical significance was not achieved after treatment. Although no statistically significant improvements were observed in SSR parameters, slightly decreased amplitudes and increased habituation of SSR were noted at the end of the treatment. The present study shows that the local steroid injection results in improvement in NCSs values, but the F-wave parameters were not effectual in short-term outcome of CTS treatment. These findings suggest that the sensory latency differences between the median and the ulnar wrist-to-digit 4 are better parameters in the median nerve recovery after treatment than the median sensory distal latency. Furthermore, the SSR does not seem to be a sensitive method in follow-up of CTS treatment.

  6. Laboratory measurements and theoretical modeling of seismoelectric interface response and coseismic wave fields

    NARCIS (Netherlands)

    Schakel, M.D.; Smeulders, D.M.J.; Slob, E.C.; Heller, H.K.J.

    2011-01-01

    A full-waveform seismoelectric numerical model incorporating the directivity pattern of a pressure source is developed. This model provides predictions of coseismic electric fields and the electromagnetic waves that originate from a fluid/porous-medium interface. An experimental setup in which cosei

  7. Wave kinematics and response of slender offshore structures. Vol 3: Description of measuring systems

    Energy Technology Data Exchange (ETDEWEB)

    Riber, H.J.

    1999-08-01

    The report presents the measuring systems used during the measurements in the North Sea at the Tyra field. The report consists of two parts: (1) Description of the wave measuring systems (WMS); (2) Description of the load mesuring system (LMS). The developed Wave Kinematics Measuring Systems (WMS) is an acoustic system based on the pulsed incoherent Doppler technique. Basically it consists of 4 sonar stations and a control and monitoring station. The sonar stations are positioned at the seabed north of the TCP-A platform in a star configuration with one station surrounded by the other three stations in a fixed distance of 37 m. From the central sonar stations an umbilical is routed to the TCP-A platform where the control and monitoring stations is positioned in the satellite communication room. The measurement periods have been concentrated to periods with storms. It was a special emphasis to measure the wave kinematics of extremely high waves. The LMS is described in terms of geometrical data, structural properties, instrumentation, and other characteristics. (LN)

  8. Effects of delayed nonlinear response on wave packet dynamics in one-dimensional generalized Fibonacci chains

    Energy Technology Data Exchange (ETDEWEB)

    Zhang, Jianxin; Zhang, Zhenjun [Department of Physics and Institute of Theoretical Physics, Nanjing Normal University, Nanjing 210023 (China); Tong, Peiqing, E-mail: pqtong@njnu.edu.cn [Department of Physics and Institute of Theoretical Physics, Nanjing Normal University, Nanjing 210023 (China); Jiangsu Key Laboratory for Numerical Simulation of Large Scale Complex Systems, Nanjing Normal University, Nanjing 210023 (China)

    2013-07-15

    We investigate the spreading of an initially localized wave packet in one-dimensional generalized Fibonacci (GF) lattices by solving numerically the discrete nonlinear Schrödinger equation (DNLSE) with a delayed cubic nonlinear term. It is found that for short delay time, the wave packet is self-trapping in first class of GF lattices, that is, the second moment grows with time, but the corresponding participation number does not grow. However, both the second moment and the participation number grow with time for large delay time. This illuminates that the wave packet is delocalized. For the second class of GF lattices, the dynamic behaviors of wave packet depend on the strength of on-site potential. For a weak on-site potential, the results are similar to the case of the first class. For a strong on-site potential, both the second moment and the participation number does not grow with time in the regime of short delay time. In the regime of large delay time, both the second moment and the participation number exhibit stair-like growth.

  9. Response of wave-dominated and mixed-energy barriers to storms

    NARCIS (Netherlands)

    Masselink, G.; Heteren, S. van

    2014-01-01

    Wave-dominated and mixed-energy barriers are extremely dynamic landforms, responding to processes operating over a spectrum of time scales, ranging from daily-to-monthly fluctuations related to storm and post-storm conditions, to century-to-millennium-scale evolution driven by relative sea-level cha

  10. Haeundae beach in Korea: Seasonal-to-decadal wave statistics and impulsive beach responses to typhoons

    Science.gov (United States)

    Lee, Hee Jun; Do, Jong-Dae; Kim, Sun Sin; Park, Won-Kyung; Jun, Kicheon

    2016-12-01

    Haeundae Beach represents Korean pocket beaches that are currently erosional and dominated by summertime typhoons. The decadal wave characteristics 9 km offshore of Haeundae Beach were analyzed using the WAM model that was validated through the 2007 wave observations. The wave statistics modelled for 1979-2007 indicates that the seasonal mean significant wave height (H s) is highest (0.6-0.7 m) in summer due to typhoons, in contrast to the lowest (around 0.5 m) autumn analog. The wave direction is also pronouncedly seasonal with the principal bearings of SSW and NE in the summer and winter seasons, respectively. The WAM results additionally show that the H s has gradually increased over the region of Haeundae Beach since 1993. Beach profiling during June-November 2014 shows the opposite processes of the typhoon and fair-weather on beach sands. During a typhoon, foreshore sands were eroded and then accumulated as sand bars on the surf zone. In the subsequent fair-weather, the sand bars moved back to the beach resulting in the surf-zone erosion and foreshore accretion. A total of 5 cycles of these beach-wide sand movements yielded a net retreat (up to 20 m) of the shoreline associated with large foreshore erosion. However, the surf zone only slightly accumulated as a result of the sand cycles. This was attributed to the sand escape offshore from the westernmost tip of the beach. The present study may provide an important clue to understanding the erosional processes in Haeundae Beach.

  11. Item Response Theory Analyses of the Parent and Teacher Ratings of the DSM-IV ADHD Rating Scale

    Science.gov (United States)

    Gomez, Rapson

    2008-01-01

    The graded response model (GRM), which is based on item response theory (IRT), was used to evaluate the psychometric properties of the inattention and hyperactivity/impulsivity symptoms in an ADHD rating scale. To accomplish this, parents and teachers completed the DSM-IV ADHD Rating Scale (DARS; Gomez et al., "Journal of Child Psychology and…

  12. Analysing surface runoff and erosion responses to different land uses from the NE of Iberian Peninsula through rainfall simulation

    Science.gov (United States)

    Regüés, David; Arnáez, José; Badía, David; Cerdà, Artemi; Echeverría, María Teresa; Gispert, María; Lana-Renault, Noemí; Lasanta, Teodoro; León, Javier; Nadal-Romero, Estela; Pardini, Giovanni

    2014-05-01

    Rainfall simulation experiments are being used by soil scientists, geomorphologists, and hydrologist to study runoff generation and erosion processes. The use of different apparatus with different rainfall intensities and size of the wetted area contribute to determine the most vulnerable soils and land uses (Cerdá, 1998; Cerdà et al., 2009; Nadal-Romero et al., 2011; Martínez-Murillo et al., 2013; León et al., 2014). This research aims to determine the land uses that yield more sediments and water and to know the factors that control the differences. The information from 152 experiments of rainfall simulation was jointly analysed. Experiments were done in 17 land uses (natural forest, tree plantation, burned forest, scrub, meadows, crops and badlands), with contrasted exposition (north-south), and vegetation cover variety and/or density. These situations were selected from four geographic contexts (NE of Catalonia, high and medium lands from the Ebro valley and Southern range of central Pyrenees) with significant altitude variations, between 90 and 1000 meters above sea level, which represent the heterogeneity of the Mediterranean climate. The use of similar rainfall simulation apparatus, with the same spray nozzle, spraying components and plot size, favours the comparison of the results. A wide spectrum of precipitation intensities was applied, in order to reach surface runoff generation in all cases. Results showed significant differences in runoff amounts and erosion rates, which were mainly associated with land uses, even more than precipitation differences. Runoff coefficient shows an inversed exponential relationship with rainfall intensity, which is the opposite what could be previously expected (Ziadat and Taimeh, 2013). This may be only justified by land use characteristics because a direct effect between runoff generation intensity and soil degradation conditions, with respect vegetation covers features and density, was observed. In fact, even though

  13. Soil carbon response to land-use change: evaluation of a global vegetation model using observational meta-analyses

    Science.gov (United States)

    Nyawira, Sylvia S.; Nabel, Julia E. M. S.; Don, Axel; Brovkin, Victor; Pongratz, Julia

    2016-10-01

    Global model estimates of soil carbon changes from past land-use changes remain uncertain. We develop an approach for evaluating dynamic global vegetation models (DGVMs) against existing observational meta-analyses of soil carbon changes following land-use change. Using the DGVM JSBACH, we perform idealized simulations where the entire globe is covered by one vegetation type, which then undergoes a land-use change to another vegetation type. We select the grid cells that represent the climatic conditions of the meta-analyses and compare the mean simulated soil carbon changes to the meta-analyses. Our simulated results show model agreement with the observational data on the direction of changes in soil carbon for some land-use changes, although the model simulated a generally smaller magnitude of changes. The conversion of crop to forest resulted in soil carbon gain of 10 % compared to a gain of 42 % in the data, whereas the forest-to-crop change resulted in a simulated loss of -15 % compared to -40 %. The model and the observational data disagreed for the conversion of crop to grasslands. The model estimated a small soil carbon loss (-4 %), while observational data indicate a 38 % gain in soil carbon for the same land-use change. These model deviations from the observations are substantially reduced by explicitly accounting for crop harvesting and ignoring burning in grasslands in the model. We conclude that our idealized simulation approach provides an appropriate framework for evaluating DGVMs against meta-analyses and that this evaluation helps to identify the causes of deviation of simulated soil carbon changes from the meta-analyses.

  14. Site response, shallow shear-wave velocity, and damage in Los Gatos, California, from the 1989 Loma Prieta earthquake

    Science.gov (United States)

    Hartzell, S.; Carver, D.; Williams, R.A.

    2001-01-01

    Aftershock records of the 1989 Loma Prieta earthquake are used to calculate site response in the frequency band of 0.5-10 Hz at 24 locations in Los Gatos, California, on the edge of the Santa Clara Valley. Two different methods are used: spectral ratios relative to a reference site on rock and a source/site spectral inversion method. These two methods complement each other and give consistent results. Site amplification factors are compared with surficial geology, thickness of alluvium, shallow shear-wave velocity measurements, and ground deformation and structural damage resulting from the Loma Prieta earthquake. Higher values of site amplification are seen on Quaternary alluvium compared with older Miocene and Cretaceous units of Monterey and Franciscan Formation. However, other more detailed correlations with surficial geology are not evident. A complex pattern of alluvial sediment thickness, caused by crosscutting thrust faults, is interpreted as contributing to the variability in site response and the presence of spectral resonance peaks between 2 and 7 Hz at some sites. Within the range of our field measurements, there is a correlation between lower average shear-wave velocity of the top 30 m and 50% higher values of site amplification. An area of residential homes thrown from their foundations correlates with high site response. This damage may also have been aggravated by local ground deformation. Severe damage to commercial buildings in the business district, however, is attributed to poor masonry construction.

  15. Analyses of biodynamic responses of seated occupants to uncorrelated fore-aft and vertical whole-body vibration

    Science.gov (United States)

    Mandapuram, Santosh; Rakheja, Subhash; Marcotte, Pierre; Boileau, Paul-Émile

    2011-08-01

    The apparent mass and seat-to-head-transmissibility response functions of the seated human body were investigated under exposures to fore-aft ( x), vertical ( z), and combined fore-aft and vertical ( x and z) axis whole-body vibration. The coupling effects of dual-axis vibration were investigated using two different frequency response function estimators based upon the cross- and auto-spectral densities of the response and excitation signals, denoted as H1 and Hv estimators, respectively. The experiments were performed to measure the biodynamic responses to single and uncorrelated dual-axis vibration, and to study the effects of hands support, back support and vibration magnitude on the body interactions with the seatpan and the backrest, characterized in terms of apparent masses and the vibration transmitted to the head. The data were acquired with 9 subjects exposed to two different magnitudes of vibration applied along the individual x- and z-axis (0.25 and 0.4 m/s 2 rms), and along both the axis (0.28 and 0.4 m/s 2 rms along each axis) in the 0.5-20 Hz frequency range. The two methods resulted in identical single-axis responses but considerably different dual-axis responses. The dual-axis responses derived from the Hv estimator revealed notable effects of dual-axis vibration, as they comprised both the direct and cross-axis responses observed under single axis vibration. Such effect, termed as the coupling effect, was not evident in the dual-axis responses derived using the commonly used H1 estimator. The results also revealed significant effects of hands and back support conditions on the coupling effects and the measured responses. The back support constrained the upper body movements and thus showed relatively weaker coupling compared to that observed in the responses without the back support. The effect of hand support was also pronounced under the fore-aft vibration. The results suggest that a better understanding of the seated human body responses to

  16. Propagation of electromagnetic waves in stratified media with nonlinearity in both dielectric and magnetic responses.

    Science.gov (United States)

    Kim, Kihong; Phung, D K; Rotermund, F; Lim, H

    2008-01-21

    We develop a generalized version of the invariant imbedding method, which allows us to solve the electromagnetic wave equations in arbitrarily inhomogeneous stratified media where both the dielectric permittivity and magnetic permeability depend on the strengths of the electric and magnetic fields, in a numerically accurate and efficient manner. We apply our method to a uniform nonlinear slab and find that in the presence of strong external radiation, an initially uniform medium of positive refractive index can spontaneously change into a highly inhomogeneous medium where regions of positive or negative refractive index as well as metallic regions appear. We also study the wave transmission properties of periodic nonlinear media and the influence of nonlinearity on the mode conversion phenomena in inhomogeneous plasmas. We argue that our theory is very useful in the study of the optical properties of a variety of nonlinear media including nonlinear negative index media fabricated using wires and split-ring resonators.

  17. Genome-wide evolutionary response to a heat wave in Drosophila

    Science.gov (United States)

    Rodríguez-Trelles, Francisco; Tarrío, Rosa; Santos, Mauro

    2013-01-01

    Extreme climatic events can substantially affect organismal performance and Darwinian fitness. In April 2011, a strong heat wave struck extensive geographical areas of the world, including Western Europe. At that time, we happened to resume and extend a long-term time series of seasonal genetic data in the widespread fly Drosophila subobscura, which provided a unique opportunity to quantify the intensity of the genetic perturbation caused by the heat wave. We show that the spring 2011 genetic constitution of the populations transiently shifted to summer-like frequencies, and that the magnitude of the genetic anomaly quantitatively matched the temperature anomaly. The results provide compelling evidence that direct effects of rising temperature are driving adaptive evolutionary shifts, and also suggest a strong genetic resilience in this species. PMID:23740296

  18. Fast Response and High Sensitivity ZnO/glass Surface Acoustic Wave Humidity Sensors Using Graphene Oxide Sensing Layer

    Science.gov (United States)

    Xuan, Weipeng; He, Mei; Meng, Nan; He, Xingli; Wang, Wenbo; Chen, Jinkai; Shi, Tianjin; Hasan, Tawfique; Xu, Zhen; Xu, Yang; Luo, J. K.

    2014-11-01

    We report ZnO/glass surface acoustic wave (SAW) humidity sensors with high sensitivity and fast response using graphene oxide sensing layer. The frequency shift of the sensors is exponentially correlated to the humidity change, induced mainly by mass loading effect rather than the complex impedance change of the sensing layer. The SAW sensors show high sensitivity at a broad humidity range from 0.5%RH to 85%RH with SAW humidity sensors, complemented with full humidity range measurement, highlights their potential in a wide range of applications.

  19. Blast Overpressure Studies with Animals and Man: Biological Response to Complex Blast Waves

    Science.gov (United States)

    1993-10-31

    armored vehicle. 4. To investigate the relative importance of the quasi- static pressure rise component of complex waves in I producing trauma by...were to be protected were blocked with a selected I earplug. Each sheep received a preanesthetic intramuscular (IM) injection of atropine sulfate (0.44...ketamine hydrochloride (22 mg/kg), exsanguinated by severing the jugular veins and carotid I arteries, and necropsied. Each animal was assessed for

  20. An analytical stability theory for Faraday waves and the observation of the harmonic surface response

    CERN Document Server

    Müller, H W; Wagner, C; Albers, J; Knorr, K

    1996-01-01

    We present an analytical stability theory for the onset of the Faraday instability, applying over a wide frequency range between shallow water gravity and deep water capillary waves. For sufficiently thin fluid layers the surface is predicted to occur in harmonic rather than subharmonic resonance with the forcing. An experimental confirmation of this result is given. PACS: 47.20.Ma, 47.20.Gv, 47.15.Cb

  1. Numerical Study on Dynamic Response of a Horizontal Layered-Structure Rock Slope under a Normally Incident Sv Wave

    Directory of Open Access Journals (Sweden)

    Zhifa Zhan

    2017-07-01

    Full Text Available Several post-earthquake investigations have indicated that the slope structure plays a leading role in the stability of rock slopes under dynamic loads. In this paper, the dynamic response of a horizontal layered-structure rock slope under harmonic Sv wave is studied by making use of the Fast Lagrangian Analysis of Continua method (FLAC. The suitability of FLAC for studying wave transmission across rock joints is validated through comparison with analytical solutions. After parametric studies on Sv wave transmission across the horizontal layered-structure rock slope, it is found that the acceleration amplification coefficient η, which is defined as the ratio of the acceleration at the monitoring point to the value at the toe, wavily increases with an increase of the height along the slope surface. Meanwhile, the fluctuation weakens with normalized joint stiffness K increasing and enhances with normalized joint spacing ξ increasing. The acceleration amplification coefficient of the slope crest ηcrest does not monotonously increase with the increase of ξ, but decreases with the increase of K. Additionally, ηcrest is more sensitive to ξ compared to K. From the contour figures, it can also be found that the contour figures of η take on rhythm, and the effects of ξ on the acceleration amplification coefficient are more obvious compared to the effects on K.

  2. Characterizing the Long-Period ULF Wave Response to Magnetic Storms

    Science.gov (United States)

    Engebretson, M. J.; Simms, L. E.; Posch, J. L.; Hughes, W. J.

    2002-05-01

    This study presents an analysis of amplitude and bandwidth of long-period ULF wave power observed at several networks of ground magnetometer stations in the western hemisphere, at latitudes from the subauroral zone to the polar caps, during the magnetic storm intervals of September and October 1999, April and October 2000, and March-April 2001 identified by the GEM research community. The magnetometer stations in this study include the polar cap / cusp latitude arrays of MACCS and the U.S. Automated Geophysical Observatories (AGOs), and the auroral / subauroral latitude arrays of CANOPUS and the British Antarctic Survey (BAS) AGOs. Comparison of the long-period pulsations (in the Pc5 frequency range) observed on the ground to the solar wind velocity and solar wind pressure confirms previous results that high solar wind velocity correlates well with increased Pc5-band power. Each storm exhibited narrow-band Pc5 wave activity during the recovery phase, but only in the dawn-noon sector at each site. During the main phase, and at all other local times during the recovery phase, wave activity was broadband.

  3. Wave kinematics and response of slender offshore structures. Vol 2: Recommendation for design

    Energy Technology Data Exchange (ETDEWEB)

    Ottesen Hansen, N.E.

    1999-08-01

    This memorandum comprises a design recommendation for slender structures exposed to wave and current loading in the sea. It is considered as an addendum to DS 499 or the DnV Classification Notes No. 30.5. Slender structures are structures as risers, well conductors, or structures with small diameter members which are dynamically amplified or liable to hydro-elastic vibrations such as vortex induced vibrations, self-excited vibrations and other dynamic phenomena. The newer type of steel platforms have a large number of these members attached to them. The present guideline is motivated by a number of failures of conductors. Some failures took place during drilling are were caused by fatigue which developed due to hydroelastic vibrations. Other failures have been caused by clamped conductors due to strong wave forces. The recommendations are based on full scale field measurements of waves and currents and of instrumented pipes in the North Sea both for high and for low Keulegan-Carpenter numbers. The measurements have been made under realistic storm conditions, which means that the recommendations are fully verified. (au)

  4. The quasi 2 day wave response in TIME-GCM nudged with NOGAPS-ALPHA

    Science.gov (United States)

    Wang, Jack C.; Chang, Loren C.; Yue, Jia; Wang, Wenbin; Siskind, D. E.

    2017-05-01

    The quasi 2 day wave (QTDW) is a traveling planetary wave that can be enhanced rapidly to large amplitudes in the mesosphere and lower thermosphere (MLT) region during the northern winter postsolstice period. In this study, we present five case studies of QTDW events during January and February 2005, 2006 and 2008-2010 by using the Thermosphere-Ionosphere-Mesosphere Electrodynamics-General Circulation Model (TIME-GCM) nudged with the Navy Operational Global Atmospheric Prediction System-Advanced Level Physics High Altitude (NOGAPS-ALPHA) Weather Forecast Model. With NOGAPS-ALPHA introducing more realistic lower atmospheric forcing in TIME-GCM, the QTDW events have successfully been reproduced in the TIME-GCM. The nudged TIME-GCM simulations show good agreement in zonal mean state with the NOGAPS-ALPHA 6 h reanalysis data and the horizontal wind model below the mesopause; however, it has large discrepancies in the tropics above the mesopause. The zonal mean zonal wind in the mesosphere has sharp vertical gradients in the nudged TIME-GCM. The results suggest that the parameterized gravity wave forcing may need to be retuned in the assimilative TIME-GCM.

  5. The influence of cochlear traveling wave and neural adaptation on auditory brainstem responses

    DEFF Research Database (Denmark)

    Junius, D.; Dau, Torsten

    2005-01-01

    The present study investigates the relationship between evoked responses to transient broadband chirps and responses to the same chirps when embedded in longer-duration stimuli. It examines to what extent the responses to the composite stimuli can be explained by a linear superposition of the res...

  6. Investigation of the Air-Wave-Sea Interaction Modes Using an Airborne Doppler Wind Lidar: Analyses of the HRDL Data Taken During DYNAMO

    Science.gov (United States)

    2012-09-30

    an Airborne Doppler Wind Lidar: Analyses of the HRDL data taken during DYNAMO George D. Emmitt Simpson Weather Associates, Inc. 809 E...the DYNAMO field campaign in order to make comparisons with existing airborne DWL measurements (TODWL) and to conduct investigations into the...data could be applied to the shipboard HRDL observations taken during DYNAMO . A second objective was to use the HRDL data and the W band radar data

  7. Analysing local-level responses to migration and urban health in Hillbrow: the Johannesburg Migrant Health Forum.

    Science.gov (United States)

    Vearey, Jo; Thomson, Kirsten; Sommers, Theresa; Sprague, Courtenay

    2017-07-04

    Johannesburg is home to a diverse migrant population and a range of urban health challenges. Locally informed and implemented responses to migration and health that are sensitive to the particular needs of diverse migrant groups are urgently required. In the absence of a coordinated response to migration and health in the city, the Johannesburg Migrant Health Forum (MHF) - an unfunded informal working group of civil society actors - was established in 2008. We assess the impact, contributions and challenges of the MHF on the development of local-level responses to migration and urban health in Johannesburg to date. In this Commentary, we draw on data from participant observation in MHF meetings and activities, a review of core MHF documents, and semi-structured interviews conducted with 15 MHF members.The MHF is contributing to the development of local-level migration and health responses in Johannesburg in three key ways: (1) tracking poor quality or denial of public services to migrants; (2) diverse organisational membership linking the policy process with community experiences; and (3) improving service delivery to migrant clients through participation of diverse service providers and civil society organisations in the Forum. Our findings indicate that the MHF has a vital role to play in supporting the development of appropriate local responses to migration and health in a context of continued - and increasing - migration, and against the backdrop of rising anti-immigrant sentiments.

  8. Datasets for transcriptomic analyses of maize leaves in response to Asian corn borer feeding and/or jasmonic acid

    Science.gov (United States)

    Corn is one of the most widely grown crops throughout the world. However, many corn fields develop pest problems such as corn borers every year that seriously affect its yield and quality. Corn's response to initial insect damage involves a variety of changes to the levels of defensive enzymes, toxi...

  9. South and North: DIF Analyses of University-Student Responses to the Emotional Skills and Competence Questionnaire

    Directory of Open Access Journals (Sweden)

    Bo Molander

    2011-12-01

    Full Text Available In a study of the Emotional Skills and Competence Questionnaire instrument (ESCQ; Takšić, 1998 three samples of university students from Balkan countries (Croatia, Serbia, and Slovenia were contrasted with two samples of university students from Nordic countries (Finland and Sweden. In total, 1978 students participated. Effects of country and gender were obtained from the ESCQ total scores, as well as from the subscale scores. The subsequent analyses of item bias, that is, differential item functioning (DIF, revealed a number of DIF items in pair wise comparisons of the samples, thus creating doubts about the fairness in comparing mean scores. Further analyses of the DIF items showed, however, that most of the item curve functions were uniform, and that effect sizes were low. It was also shown that the number of DIF items depended on which countries were compared. Spearman correlations between measures of number of DIF items and cultural values as measured by World Value Survey data were very high. Implications of these findings for future cross-cultural studies of the ESCQ instrument are discussed.

  10. Immediate Dose-Response Effect of High-Energy Versus Low-Energy Extracorporeal Shock Wave Therapy on Cutaneous Microcirculation.

    Science.gov (United States)

    Kraemer, Robert; Sorg, Heiko; Forstmeier, Vinzent; Knobloch, Karsten; Liodaki, Eirini; Stang, Felix Hagen; Mailaender, Peter; Kisch, Tobias

    2016-12-01

    Elucidation of the precise mechanisms and therapeutic options of extracorporeal shock wave therapy (ESWT) is only at the beginning. Although immediate real-time effects of ESWT on cutaneous hemodynamics have recently been described, the dose response to different ESWT energies in cutaneous microcirculation has never been examined. Thirty-nine Sprague-Dawley rats were randomly assigned to three groups that received either focused high-energy shock waves (group A: total of 1000 impulses, 10 J) to the lower leg of the hind limb, focused low-energy shock waves (group B: total of 300 impulses, 1 J) or placebo shock wave treatment (group C: 0 impulses, 0 J) using a multimodality shock wave delivery system (Duolith SD-1 T-Top, Storz Medical, Tägerwilen, Switzerland). Immediate microcirculatory effects were assessed with the O2C (oxygen to see) system (LEA Medizintechnik, Giessen, Germany) before and for 20 min after application of ESWT. Cutaneous tissue oxygen saturation increased significantly higher after high-energy ESWT than after low-energy and placebo ESWT (A: 29.4% vs. B: 17.3% vs. C: 3.3%; p = 0.003). Capillary blood velocity was significantly higher after high-energy ESWT and lower after low-energy ESWT versus placebo ESWT (group A: 17.8% vs. group B: -22.1% vs. group C: -5.0%, p = 0.045). Post-capillary venous filling pressure was significantly enhanced in the high-energy ESWT group in contrast to the low-energy ESWT and placebo groups (group A: 25% vs. group B: 2% vs. group C: -4%, p = 0.001). Both high-energy and low-energy ESWT affect cutaneous hemodynamics in a standard rat model. High-energy ESWT significantly increases parameters of cutaneous microcirculation immediately after application, resulting in higher tissue oxygen saturation, venous filling pressure and blood velocity, which suggests higher tissue perfusion with enhanced oxygen saturation, in contrast to low-energy as well as placebo ESWT. Low-energy ESWT also increased tissue oxygen

  11. Datasets for transcriptomic analyses of maize leaves in response to Asian corn borer feeding and/or jasmonic acid

    Directory of Open Access Journals (Sweden)

    Yuliang Zhang

    2016-06-01

    Full Text Available Corn is one of the most widely grown crops throughout the world. However, many corn fields develop pest problems such as corn borers every year that seriously affect its yield and quality. Corn′s response to initial insect damage involves a variety of changes to the levels of defensive enzymes, toxins, and communicative volatiles. Such a dramatic change secondary metabolism necessitates the regulation of gene expression at the transcript level. In this paper, we summarized the datasets of the transcriptome of corn plants in response to corn stalk borers (Ostrinia furnacalis and/or methyl jasmonate (MeJA. Altogether, 39, 636 genes were found to be differentially expressed. The sequencing data are available in the NCBI SRA database under accession number SRS965087. Our dataset will provide more scientific and valuable information for future work such as the study of the functions of important genes or proteins and develop new insect-resistant maize varieties.

  12. Study on dynamic response of embedded long span corrugated steel culverts using scaled model shaking table tests and numerical analyses

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    A series of scaled-model shaking table tests and its simulation analyses using dynamic finite element method were performed to clarify the dynamic behaviors and the seismic stability of embedded corrugated steel culverts due to strong earthquakes like the 1995 Hyogoken-nanbu earthquake. The dynamic strains of the embedded culvert models and the seismic soil pressure acting on the models due to sinusoidal and random strong motions were investigated. This study verified that the corrugated culvert model was subjected to dynamic horizontal forces (lateral seismic soil pressure) from the surrounding ground,which caused the large bending strains on the structure; and that the structures do not exceed the allowable plastic deformation and do not collapse completely during strong earthquake like Hyogoken-nanbu earthquake. The results obtained are useful for design and construction of embedded long span corrugated steel culverts in seismic regions.

  13. A Bioinformatics Pipeline for the Analyses of Viral Escape Dynamics and Host Immune Responses during an Infection

    Directory of Open Access Journals (Sweden)

    Preston Leung

    2014-01-01

    Full Text Available Rapidly mutating viruses, such as hepatitis C virus (HCV and HIV, have adopted evolutionary strategies that allow escape from the host immune response via genomic mutations. Recent advances in high-throughput sequencing are reshaping the field of immuno-virology of viral infections, as these allow fast and cheap generation of genomic data. However, due to the large volumes of data generated, a thorough understanding of the biological and immunological significance of such information is often difficult. This paper proposes a pipeline that allows visualization and statistical analysis of viral mutations that are associated with immune escape. Taking next generation sequencing data from longitudinal analysis of HCV viral genomes during a single HCV infection, along with antigen specific T-cell responses detected from the same subject, we demonstrate the applicability of these tools in the context of primary HCV infection. We provide a statistical and visual explanation of the relationship between cooccurring mutations on the viral genome and the parallel adaptive immune response against HCV.

  14. iTRAQ-based quantitative proteomic analyses on the gender-specific responses in mussel Mytilus galloprovincialis to tetrabromobisphenol A.

    Science.gov (United States)

    Ji, Chenglong; Wu, Huifeng; Wei, Lei; Zhao, Jianmin

    2014-12-01

    Tetrabromobisphenol A (TBBPA) accounts for the largest production of brominated flame-retardants (BFRs) along the Laizhou Bay in China and is the most widely used BFR in industrial products. It can induce diverse toxicities including hepatotoxicity, nephrotoxicity, neurotoxicity and endocrine disrupting effects in mammalian and fish models. In this work, we applied iTRAQ-based proteomics to investigate the gender-specific responses in mussel Mytilus galloprovincialis to TBBPA. Thirty-one proteins were differentially expressed in hepatopancreas between male and female mussels, which clearly indicated the biological differences between male and female mussels at the protein level. After exposure of TBBPA (18.4 nmol/L) for one month, a total of 60 proteins were differentially expressed in response to the TBBPA treatment in mussel hepatopancreas, among which 33 and 29 proteins were significantly altered in TBBPA-treated male and female mussel samples, respectively. Only two of the 60 proteins were commonly altered in both male and female mussel samples exposed to TBBPA. Based on KEGG analysis, these differentially expressed proteins of TBBPA-induced effects were assigned to several groups, including cytoskeleton, reproduction and development, metabolism, signal transduction, gene expression, stress response and apoptosis. Overall, results indicated that TBBPA exposure could induce apoptosis, oxidative and immune stresses and disruption in energy, protein and lipid metabolisms in both male and female mussels with different mechanisms. This work suggested that the gender differences should be considered in ecotoxicoproteomics.

  15. Genome-Wide Analyses of the Soybean F-Box Gene Family in Response to Salt Stress.

    Science.gov (United States)

    Jia, Qi; Xiao, Zhi-Xia; Wong, Fuk-Ling; Sun, Song; Liang, Kang-Jing; Lam, Hon-Ming

    2017-04-12

    The F-box family is one of the largest gene families in plants that regulate diverse life processes, including salt responses. However, the knowledge of the soybean F-box genes and their roles in salt tolerance remains limited. Here, we conducted a genome-wide survey of the soybean F-box family, and their expression analysis in response to salinity via in silico analysis of online RNA-sequencing (RNA-seq) data and quantitative reverse-transcription polymerase chain reaction (qRT-PCR) to predict their potential functions. A total of 725 potential F-box proteins encoded by 509 genes were identified and classified into 9 subfamilies. The gene structures, conserved domains and chromosomal distributions were characterized. There are 76 pairs of duplicate genes identified, including genome-wide segmental and tandem duplication events, which lead to the expansion of the number of F-box genes. The in silico expression analysis showed that these genes would be involved in diverse developmental functions and play an important role in salt response. Our qRT-PCR analysis confirmed 12 salt-responding F-box genes. Overall, our results provide useful information on soybean F-box genes, especially their potential roles in salt tolerance.

  16. Turning the tide or surfing the wave? Responsible Research and Innovation, fundamental rights and neoliberal virtues.

    Science.gov (United States)

    Arnaldi, Simone; Gorgoni, Guido

    2016-12-01

    The notion of Responsible Research and Innovation (RRI) has increasingly attracted attention in the academic literature. Up until now, however, the literature has focused on clarifying the principles for which research and innovation are responsible and on examining the conditions that account for managing them responsibly. Little attention has been reserved to exploring the political-economic context in which the notion of RRI has become progressively more prominent. This article tries to address this aspect and suggests some preliminary considerations on the connections between the specific understanding of responsibility in RRI and the framing of responsibility in what has been synthetically defined as 'neoliberalism'. To do so, we try to illustrate how the idea of responsibility has evolved over time so that the specific characteristics of RRI can be better highlighted. These characteristics will then be discussed against the features of neoliberalism and its understanding of responsibility. Eventually, we reaffirm a view of RRI centred on fundamental rights as a possible point of departure between these two perspectives on responsibility.

  17. Integrated expression profiling and ChIP-seq analyses of the growth inhibition response program of the androgen receptor.

    Directory of Open Access Journals (Sweden)

    Biaoyang Lin

    Full Text Available BACKGROUND: The androgen receptor (AR plays important roles in the development of male phenotype and in different human diseases including prostate cancers. The AR can act either as a promoter or a tumor suppressor depending on cell types. The AR proliferative response program has been well studied, but its prohibitive response program has not yet been thoroughly studied. METHODOLOGY/PRINCIPAL FINDINGS: Previous studies found that PC3 cells expressing the wild-type AR inhibit growth and suppress invasion. We applied expression profiling to identify the response program of PC3 cells expressing the AR (PC3-AR under different growth conditions (i.e. with or without androgens and at different concentration of androgens and then applied the newly developed ChIP-seq technology to identify the AR binding regions in the PC3 cancer genome. A surprising finding was that the comparison of MOCK-transfected PC3 cells with AR-transfected cells identified 3,452 differentially expressed genes (two fold cutoff even without the addition of androgens (i.e. in ethanol control, suggesting that a ligand independent activation or extremely low-level androgen activation of the AR. ChIP-Seq analysis revealed 6,629 AR binding regions in the cancer genome of PC3 cells with an FDR (false discovery rate cut off of 0.05. About 22.4% (638 of 2,849 can be mapped to within 2 kb of the transcription start site (TSS. Three novel AR binding motifs were identified in the AR binding regions of PC3-AR cells, and two of them share a core consensus sequence CGAGCTCTTC, which together mapped to 27.3% of AR binding regions (1,808/6,629. In contrast, only about 2.9% (190/6,629 of AR binding sites contains the canonical AR matrix M00481, M00447 and M00962 (from the Transfac database, which is derived mostly from AR proliferative responsive genes in androgen dependent cells. In addition, we identified four top ranking co-occupancy transcription factors in the AR binding regions, which

  18. Exposure–Response Analyses of Asbestos and Lung Cancer Subtypes in a Pooled Analysis of Case–Control Studies

    Science.gov (United States)

    Vermeulen, Roel; Schüz, Joachim; Kromhout, Hans; Pesch, Beate; Peters, Susan; Behrens, Thomas; Portengen, Lützen; Mirabelli, Dario; Gustavsson, Per; Kendzia, Benjamin; Almansa, Josue; Luzon, Veronique; Vlaanderen, Jelle; Stücker, Isabelle; Guida, Florence; Consonni, Dario; Caporaso, Neil; Landi, Maria Teresa; Field, John; Brüske, Irene; Wichmann, Heinz-Erich; Siemiatycki, Jack; Parent, Marie-Elise; Richiardi, Lorenzo; Merletti, Franco; Jöckel, Karl-Heinz; Ahrens, Wolfgang; Pohlabeln, Hermann; Plato, Nils; Tardón, Adonina; Zaridze, David; McLaughlin, John; Demers, Paul; Szeszenia-Dabrowska, Neonila; Lissowska, Jolanta; Rudnai, Peter; Fabianova, Eleonora; Stanescu Dumitru, Rodica; Bencko, Vladimir; Foretova, Lenka; Janout, Vladimir; Boffetta, Paolo; Bueno-de-Mesquita, Bas; Forastiere, Francesco; Brüning, Thomas; Straif, Kurt

    2017-01-01

    Background: Evidence is limited regarding risk and the shape of the exposure–response curve at low asbestos exposure levels. We estimated the exposure–response for occupational asbestos exposure and assessed the joint effect of asbestos exposure and smoking by sex and lung cancer subtype in general population studies. Methods: We pooled 14 case–control studies conducted in 1985–2010 in Europe and Canada, including 17,705 lung cancer cases and 21,813 controls with detailed information on tobacco habits and lifetime occupations. We developed a quantitative job-exposure-matrix to estimate job-, time period-, and region-specific exposure levels. Fiber-years (ff/ml-years) were calculated for each subject by linking the matrix with individual occupational histories. We fit unconditional logistic regression models to estimate odds ratios (ORs), 95% confidence intervals (CIs), and trends. Results: The fully adjusted OR for ever-exposure to asbestos was 1.24 (95% CI, 1.18, 1.31) in men and 1.12 (95% CI, 0.95, 1.31) in women. In men, increasing lung cancer risk was observed with increasing exposure in all smoking categories and for all three major lung cancer subtypes. In women, lung cancer risk for all subtypes was increased in current smokers (ORs ~two-fold). The joint effect of asbestos exposure and smoking did not deviate from multiplicativity among men, and was more than additive among women. Conclusions: Our results in men showed an excess risk of lung cancer and its subtypes at low cumulative exposure levels, with a steeper exposure–response slope in this exposure range than at higher, previously studied levels. (See video abstract at, http://links.lww.com/EDE/B161.) PMID:28141674

  19. Electromagnetic Response of High-Frequency Gravitational Waves by Coupling Open Resonant Cavity

    Institute of Scientific and Technical Information of China (English)

    LI Fang-Yu; CHEN Ying; WANG Ping

    2007-01-01

    We present a new detecting scheme of high-frequency gravitational waves(HFGWs) in the GHz band,the scheme consists of a high-quality-factor open microwave cavity,a static magnetic field passing through the cavity and an electromagnetic (EM)normal mode stored in the cavity.It is found that under the resonant condition firstand second-order perturbation EM effects have almost the same detecting sensitivity to the HFGWs in the GHz band (h~10-26,v~5GHz),but the former contains more information from the HFGWs.We akso provide a very brief review for possible improving way of the sensitivity.This scheme would be Highly complementary to other schemes of detecting the HFGWs.

  20. Impact of Acoustic Standing Waves on Structural Responses: Reverberant Acoustic Testing (RAT) vs. Direct Field Acoustic Testing (DFAT)

    Science.gov (United States)

    Kolaini, Ali R.; Doty, Benjamin; Chang, Zensheu

    2012-01-01

    Loudspeakers have been used for acoustic qualification of spacecraft, reflectors, solar panels, and other acoustically responsive structures for more than a decade. Limited measurements from some of the recent speaker tests used to qualify flight hardware have indicated significant spatial variation of the acoustic field within the test volume. Also structural responses have been reported to differ when similar tests were performed using reverberant chambers. To address the impact of non-uniform acoustic field on structural responses, a series of acoustic tests were performed using a flat panel and a 3-ft cylinder exposed to the field controlled by speakers and repeated in a reverberant chamber. The speaker testing was performed using multi-input-single-output (MISO) and multi-input-multi-output (MIMO) control schemes with and without the test articles. In this paper the spatial variation of the acoustic field due to acoustic standing waves and their impacts on the structural responses in RAT and DFAT (both using MISO and MIMO controls for DFAT) are discussed in some detail.

  1. Highly sensitive and ultrafast response surface acoustic wave humidity sensor based on electrospun polyaniline/poly(vinyl butyral) nanofibers

    Energy Technology Data Exchange (ETDEWEB)

    Lin Qianqian [Department of Polymer Science and Engineering, Cyrus Tang Center for Sensor Materials and Applications, Zhejiang University, MOE Key Laboratory of Macromolecule Synthesis and Functionalization, Hangzhou 310027 (China); Li Yang, E-mail: liyang@zju.edu.cn [Department of Polymer Science and Engineering, Cyrus Tang Center for Sensor Materials and Applications, Zhejiang University, MOE Key Laboratory of Macromolecule Synthesis and Functionalization, Hangzhou 310027 (China); Yang Mujie [Department of Polymer Science and Engineering, Cyrus Tang Center for Sensor Materials and Applications, Zhejiang University, MOE Key Laboratory of Macromolecule Synthesis and Functionalization, Hangzhou 310027 (China)

    2012-10-20

    Highlights: Black-Right-Pointing-Pointer Polyanline/poly(vinyl butyral) nanofibers are prepared by electrospinning. Black-Right-Pointing-Pointer Nanofiber-based SAW humidity sensor show high sensitivity and ultrafast response. Black-Right-Pointing-Pointer The SAW sensor can detect very low humidity. - Abstract: Polyaniline (PANi) composite nanofibers were deposited on surface acoustic wave (SAW) resonator with a central frequency of 433 MHz to construct humidity sensors. Electrospun nanofibers of poly(methyl methacrylate), poly(vinyl pyrrolidone), poly(ethylene oxide), poly(vinylidene fluoride), poly(vinyl butyral) (PVB) were characterized by scanning electron microscopy, and humidity response of corresponding SAW humidity sensors were investigated. The results indicated that PVB was suitable as a matrix to form nanofibers with PANi by electrospinning (ES). Electrospun PANi/PVB nanofibers exhibited a core-sheath structure as revealed by transmittance electron microscopy. Effects of ES collection time on humidity response of SAW sensor based on PANi/PVB nanofibers were examined at room temperature. The composite nanofiber sensor exhibited very high sensitivity of {approx}75 kHz/%RH from 20 to 90%RH, ultrafast response (1 s and 2 s for humidification and desiccation, respectively) and good sensing linearity. Furthermore, the sensor could detect humidity as low as 0.5%RH, suggesting its potentials for low humidity detection. Attempts were done to explain the attractive humidity sensing performance of the sensor by considering conductivity, hydrophilicity, viscoelasticity and morphology of the polymer composite nanofibers.

  2. Physiological and proteomic analyses of leaves from the halophyte Tangut Nitraria reveals diverse response pathways critical for high salinity tolerance

    Directory of Open Access Journals (Sweden)

    Tielong eCheng

    2015-02-01

    Full Text Available Soil salinization poses a serious threat to the environment and agricultural productivity worldwide. Studies on the physiological and molecular mechanisms of salinity tolerance in halophytic plants provide valuable information to enhance their salt tolerance. Tangut Nitraria is a widely distributed halophyte in saline–alkali soil in the northern areas of China. In this study, we used a proteomic approach to investigate the molecular pathways of the high salt tolerance of T. Nitraria. We analyzed the changes in biomass, photosynthesis, and redox-related enzyme activities in T. Nitraria leaves from plant seedlings treated with high salt concentration. Comparative proteomic analysis of the leaves revealed that the expression of 71 proteins was significantly altered after salinity treatments of T. Nitraria. These salinity-responsive proteins were mainly involved in photosynthesis, redox homeostasis, stress/defense, carbohydrate and energy metabolism, protein metabolism, signal transduction, and membrane transport. Results showed that the reduction of photosynthesis under salt stress was attributed to the down-regulation of the enzymes and proteins involved in the light reaction and Calvin cycle. Protein–protein interaction analysis revealed that the proteins involved in redox homeostasis, photosynthesis, and energy metabolism constructed two types of response networks to high salt stress. T. Nitraria plants developed diverse mechanisms for scavenging reactive oxygen species in their leaves to cope with stress induced by high salinity. This study provides important information regarding the salt tolerance of the halophyte T. Nitraria.

  3. Comparative transcriptional and anatomical analyses of tolerant rough lemon and susceptible sweet orange in response to 'Candidatus Liberibacter asiaticus' infection.

    Science.gov (United States)

    Fan, Jing; Chen, Chunxian; Yu, Qibin; Khalaf, Abeer; Achor, Diann S; Brlansky, Ron H; Moore, Gloria A; Li, Zheng-Guo; Gmitter, Frederick G

    2012-11-01

    Although there are no known sources of genetic resistance, some Citrus spp. are reportedly tolerant to huanglongbing (HLB), presumably caused by 'Candidatus Liberibacter asiaticus'. Time-course transcriptional analysis of tolerant rough lemon (Citrus jambhiri) and susceptible sweet orange (C. sinensis) in response to 'Ca. L. asiaticus' infection showed more genes differentially expressed in HLB-affected rough lemon than sweet orange at early stages but substantially fewer at late time points, possibly a critical factor underlying differences in sensitivity to 'Ca. L. asiaticus'. Pathway analysis revealed that stress responses were distinctively modulated in rough lemon and sweet orange. Although microscopic changes (e.g., callose deposition in sieve elements and phloem cell collapse) were found in both infected species, remarkably, phloem transport activity in midribs of source leaves in rough lemon was much less affected by HLB than in sweet orange. The difference in phloem cell transport activities is also implicated in the differential sensitivity to HLB between the two species. The results potentially lead to identification of key genes and the genetic mechanism in rough lemon to restrain disease development and maintain (or recover) phloem transport activity. These potential candidate genes may be used for improving citrus tolerance (or even resistance) to HLB by genetic engineering.

  4. Application of Entropy and Fractal Dimension Analyses to the Pattern Recognition of Contaminated Fish Responses in Aquaculture

    Directory of Open Access Journals (Sweden)

    Harkaitz Eguiraun

    2014-11-01

    Full Text Available The objective of the work was to develop a non-invasive methodology for image acquisition, processing and nonlinear trajectory analysis of the collective fish response to a stochastic event. Object detection and motion estimation were performed by an optical flow algorithm in order to detect moving fish and simultaneously eliminate background, noise and artifacts. The Entropy and the Fractal Dimension (FD of the trajectory followed by the centroids of the groups of fish were calculated using Shannon and permutation Entropy and the Katz, Higuchi and Katz-Castiglioni’s FD algorithms respectively. The methodology was tested on three case groups of European sea bass (Dicentrarchus labrax, two of which were similar (C1 control and C2 tagged fish and very different from the third (C3, tagged fish submerged in methylmercury contaminated water. The results indicate that Shannon entropy and Katz-Castiglioni were the most sensitive algorithms and proved to be promising tools for the non-invasive identification and quantification of differences in fish responses. In conclusion, we believe that this methodology has the potential to be embedded in online/real time architecture for contaminant monitoring programs in the aquaculture industry.

  5. Coordinating metabolite changes with our perception of plant abiotic stress responses: emerging views revealed by integrative-omic analyses.

    Science.gov (United States)

    Radomiljac, Jordan D; Whelan, James; van der Merwe, Margaretha

    2013-09-06

    Metabolic configuration and adaptation under a range of abiotic stresses, including drought, heat, salinity, cold, and nutrient deprivation, are subjected to an intricate span of molecular pathways that work in parallel in order to enhance plant fitness and increase stress tolerance. In recent years, unprecedented advances have been made in identifying and linking different abiotic stresses, and the current challenge in plant molecular biology is deciphering how the signaling responses are integrated and transduced throughout metabolism. Metabolomics have often played a fundamental role in elucidating the distinct and overlapping biochemical changes that occur in plants. However, a far greater understanding and appreciation of the complexity in plant metabolism under specific stress conditions have become apparent when combining metabolomics with other-omic platforms. This review focuses on recent advances made in understanding the global changes occurring in plant metabolism under abiotic stress conditions using metabolite profiling as an integrated discovery platform.

  6. Identification and comparative analyses of myocardial miRNAs involved in the fetal response to maternal obesity

    Science.gov (United States)

    Muralimanoharan, Sribalasubashini; Huffman, Steven; Cox, Laura A.; Nathanielsz, Peter W.; Myatt, Leslie; Nijland, Mark J.

    2013-01-01

    Human and animal studies show that suboptimal intrauterine environments lead to fetal programming, predisposing offspring to disease in later life. Maternal obesity has been shown to program offspring for cardiovascular disease (CVD), diabetes, and obesity. MicroRNAs (miRNAs) are small, noncoding RNA molecules that act as key regulators of numerous cellular processes. Compelling evidence links miRNAs to the control of cardiac development and etiology of cardiac pathology; however, little is known about their role in the fetal cardiac response to maternal obesity. Our aim was to sequence and profile the cardiac miRNAs that are dysregulated in the hearts of baboon fetuses born to high fat/high fructose-diet (HFD) fed mothers for comparison with fetal hearts from mothers eating a regular diet. Eighty miRNAs were differentially expressed. Of those, 55 miRNAs were upregulated and 25 downregulated with HFD. Twenty-two miRNAs were mapped to human; 14 of these miRNAs were previously reported to be dysregulated in experimental or human CVD. We used an Ingenuity Pathway Analysis to integrate miRNA profiling and bioinformatics predictions to determine miRNA-regulated processes and genes potentially involved in fetal programming. We found a correlation between miRNA expression and putative gene targets involved in developmental disorders and CVD. Cellular death, growth, and proliferation were the most affected cellular functions in response to maternal obesity. Thus, the current study reveals significant alterations in cardiac miRNA expression in the fetus of obese baboons. The epigenetic modifications caused by adverse prenatal environment may represent one of the mechanisms underlying fetal programming of CVD. PMID:23922128

  7. Biochemical and proteomic analyses of the physiological response induced by individual housing in gilts provide new potential stress markers.

    Science.gov (United States)

    Marco-Ramell, Anna; Arroyo, Laura; Peña, Raquel; Pato, Raquel; Saco, Yolanda; Fraile, Lorenzo; Bendixen, Emøke; Bassols, Anna

    2016-11-25

    The objective assessment of animal stress and welfare requires proper laboratory biomarkers. In this work, we have analyzed the changes in serum composition in gilts after switching their housing, from pen to individual stalls, which is generally accepted to cause animal discomfort. Blood and saliva samples were collected a day before and up to four days after changing the housing system. Biochemical analyses showed adaptive changes in lipid and protein metabolism after the housing switch, whereas cortisol and muscular markers showed a large variability between animals. 2D-DIGE and iTRAQ proteomic approaches revealed variations in serum protein composition after changing housing and diet of gilts. Both techniques showed alterations in two main homeostatic mechanisms: the innate immune and redox systems. The acute phase proteins haptoglobin, apolipoprotein A-I and α1-antichymotrypsin 3, and the antioxidant enzyme peroxiredoxin 2 were found differentially expressed by 2D-DIGE. Other proteins related to the innate immune system, including lactotransferrin, protegrin 3 and galectin 1 were also identified by iTRAQ, as well as oxidative stress enzymes such as peroxiredoxin 2 and glutathione peroxidase 3. Proteomics also revealed the decrease of apolipoproteins, and the presence of intracellular proteins in serum, which may indicate physical injury to tissues. Housing of gilts in individual stalls and diet change increase lipid and protein catabolism, oxidative stress, activate the innate immune system and cause a certain degree of tissue damage. We propose that valuable assays for stress assessment in gilts may be based on a score composed by a combination of salivary cortisol, lipid metabolites, innate immunity and oxidative stress markers and intracellular proteins.

  8. Performance of the Family Satisfaction with the End-of-Life Care (FAMCARE) measure in an ethnically diverse cohort: psychometric analyses using item response theory.

    Science.gov (United States)

    Teresi, Jeanne A; Ornstein, Katherine; Ocepek-Welikson, Katja; Ramirez, Mildred; Siu, Albert

    2014-02-01

    The Family Satisfaction with End-of-Life Care (FAMCARE) has been used widely among caregivers to individuals with cancer. The aim of this study was to evaluate the psychometric properties of this measure using item response theory (IRT). The analytic sample was comprised of caregivers to 1,983 patients with advanced cancer. Among the patients, 56 % were females, with mean age 59.9 years (s.d. = 11.8), 20 % were non-Hispanic Black. The majority were family members either living with (44 %) or not living with (35 %) the patient. Factor analyses and IRT were used to examine the dimensionality, information, and reliability of the FAMCARE. Although a bi-factor model fit the data slightly better than did a unidimensional model, the loadings on the group factors were very low. Thus, a unidimensional model appears to provide adequate representation for the item set. The reliability estimates, calculated along the satisfaction (theta) continuum, were adequate (>0.80) for all levels of theta for which subjects had scores. Examination of the category response functions from IRT showed overlap in the lower categories with little unique information provided; moreover, the categories were not observed to be interval. Based on these analyses, a three-response category format was recommended: very satisfied, satisfied, and not satisfied. Most information was provided in the range indicative of either dissatisfaction or high satisfaction. These analyses support the use of fewer response categories and provide item parameters that form a basis for developing shorter-form scales. Such a revision has the potential to reduce respondent burden.

  9. An Experimental Study on A Trapezoidal Pendulum Wave Energy Converter in Regular Waves

    Institute of Scientific and Technical Information of China (English)

    王冬姣; 邱守强; 叶家玮

    2015-01-01

    Experimental studies were conducted on a trapezoidal pendulum wave energy converter in regular waves. To obtain the incident wave height, the analytical method (AM) was used to separate the incident and reflected waves propagating in a wave flume by analysing wave records measured at two locations. The response amplitude operator (RAO), primary conversion efficiency and the total conversion efficiency of the wave energy converter were studied; furthermore, the power take-off damping coefficients corresponding to the load resistances in the experiment were also obtained. The findings demonstrate that the natural period for a pendulum wave energy converter is relatively large. A lower load resistance gives rise to a larger damping coefficient. The model shows relatively higher wave energy conversion efficiency in the range of 1.0-1.2 s for the incident wave period. The maximum primary conversion efficiency achieved was 55.5%, and the maximum overall conversion efficiency was 39.4%.

  10. Propagation of waves in shear flows

    CERN Document Server

    Fabrikant, A L

    1998-01-01

    The state of the art in a theory of oscillatory and wave phenomena in hydrodynamical flows is presented in this book. A unified approach is used for waves of different physical origins. A characteristic feature of this approach is that hydrodynamical phenomena are considered in terms of physics; that is, the complement of the conventionally employed formal mathematical approach. Some physical concepts such as wave energy and momentum in a moving fluid are analysed, taking into account induced mean flow. The physical mechanisms responsible for hydrodynamic instability of shear flows are conside

  11. Characterization and novel analyses of acute stress response patterns in a population-based cohort of young adults: influence of gender, smoking, and BMI.

    Science.gov (United States)

    Herbison, Carly E; Henley, David; Marsh, Julie; Atkinson, Helen; Newnham, John P; Matthews, Stephen G; Lye, Stephen J; Pennell, Craig E

    2016-01-01

    Dysregulation of the biological stress response system has been implicated in the development of psychological, metabolic, and cardiovascular disease. Whilst changes in stress response are often quantified as an increase or decrease in cortisol levels, three different patterns of stress response have been reported in the literature for the Trier Social Stress Test (TSST) (reactive-responders (RR), anticipatory-responders (AR) and non-responders (NR)). However, these have never been systematically analyzed in a large population-based cohort. The aims of this study were to examine factors that contribute to TSST variation (gender, oral contraceptive use, menstrual cycle phase, smoking, and BMI) using traditional methods and novel analyses of stress response patterns. We analyzed the acute stress response of 798, 18-year-old participants from a community-based cohort using the TSST. Plasma adrenocorticotrophic hormone, plasma cortisol, and salivary cortisol levels were quantified. RR, AR, and NR patterns comprised 56.6%, 26.2%, and 17.2% of the cohort, respectively. Smokers were more likely to be NR than (RR or AR; adjusted, p stress-response patterns, in addition to other parameters vary with gender, smoking, and BMI. The distribution of these patterns has the potential to vary with adult health and disease and may represent a biomarker for future investigation.

  12. Making Waves: Seismic Waves Activities and Demonstrations

    Science.gov (United States)

    Braile, S. J.; Braile, L. W.

    2011-12-01

    The nature and propagation of seismic waves are fundamental concepts necessary for understanding the exploration of Earth's interior structure and properties, plate tectonics, earthquakes, and seismic hazards. Investigating seismic waves is also an engaging approach to learning basic principles of the physics of waves and wave propagation. Several effective educational activities and demonstrations are available for teaching about seismic waves, including the stretching of a spring to demonstrate elasticity; slinky wave propagation activities for compressional, shear, Rayleigh and Love waves; the human wave activity to demonstrate P- and S- waves in solids and liquids; waves in water in a simple wave tank; seismic wave computer animations; simple shake table demonstrations of model building responses to seismic waves to illustrate earthquake damage to structures; processing and analysis of seismograms using free and easy to use software; and seismic wave simulation software for viewing wave propagation in a spherical Earth. The use of multiple methods for teaching about seismic waves is useful because it provides reinforcement of the fundamental concepts, is adaptable to variable classroom situations and diverse learning styles, and allows one or more methods to be used for authentic assessment. The methods described here have been used effectively with a broad range of audiences, including K-12 students and teachers, undergraduate students in introductory geosciences courses, and geosciences majors.

  13. Comparative Transcriptome and iTRAQ Proteome Analyses of Citrus Root Responses to Candidatus Liberibacter asiaticus Infection.

    Directory of Open Access Journals (Sweden)

    Yun Zhong

    Full Text Available Root samples of 'Sanhu' red tangerine trees infected with and without Candidatus Liberibacter asiaticus (CLas were collected at 50 days post inoculation and subjected to RNA-sequencing and isobaric tags for relative and absolute quantification (iTRAQ to profile the differentially expressed genes (DEGs and proteins (DEPs, respectively. Quantitative real-time PCR was subsequently used to confirm the expression of 16 selected DEGs. Results showed that a total of 3956 genes and 78 proteins were differentially regulated by HLB-infection. Among the most highly up-regulated DEPs were sperm specific protein 411, copper ion binding protein, germin-like proteins, subtilisin-like proteins and serine carboxypeptidase-like 40 proteins whose transcript levels were concomitantly up-regulated as shown by RNA-seq data. Comparison between our results and those of the previously reported showed that known HLB-modulated biological pathways including cell-wall modification, protease-involved protein degradation, carbohydrate metabolism, hormone synthesis and signaling, transcription activities, and stress responses were similarly regulated by HLB infection but different or root-specific changes did exist. The root unique changes included the down-regulation in genes of ubiquitin-dependent protein degradation pathway, secondary metabolism, cytochrome P450s, UDP-glucosyl transferases and pentatricopeptide repeat containing proteins. Notably, nutrient absorption was impaired by HLB-infection as the expression of the genes involved in Fe, Zn, N and P adsorption and transportation were significantly changed. HLB-infection induced some cellular defense responses but simultaneously reduced the biosynthesis of the three major classes of secondary metabolites, many of which are known to have anti-pathogen activities. Genes involved in callose deposition were up-regulated whereas those involved in callose degradation were also up-regulated, indicating that the sieve tube

  14. Experimental study on the response of very large floating structures (VLFS) in wave; Choogata futaishiki kaiyo kozobutsu no harochu oto ni kansuru jikkenteki kenkyu

    Energy Technology Data Exchange (ETDEWEB)

    Ota, M.; Ikegami, H.; Yamaguchi, Y. [Mitsubishi Heavy Industries, Ltd., Tokyo (Japan)

    1997-10-01

    The elastic response of VLFS of 1200m long in wave was studied experimentally using a water tank and integral elastic model of 1/80 scale. As offshore airport, a ultra- thin box type floating structure of 5km long, 1km wide and several meter thick is used, and the effect of elasticity is not negligible for such a structure. The experiment used a water tank of 160m long, 30m wide and 3.1m deep. Supposing a water depth of 20m for real VLFSs, the experiment was carried out mainly in a local shallow water area prepared with a temporary bottom together with that in a deep water area. A simple mooring equipment with a linear spring equivalent to real VLFSs was used. The integral floating model was prepared by not mechanical but welded junction to obtain uniform elasticity. The response in wave showed a complicated 3-D behavior, offering useful data for verification of a behavior estimation method. The response was nearly equal between shallow and deep water areas at the same wave length, and the response amplitude in regular waves was equivalent to the significant amplitude in long and short crested irregular waves. 7 refs., 8 figs., 3 tabs.

  15. Transcriptional response of Desulfatibacillum alkenivorans AK-01 to growth on alkanes: insights from RT-qPCR and microarray analyses.

    Science.gov (United States)

    Herath, Anjumala; Wawrik, Boris; Qin, Yujia; Zhou, Jizhong; Callaghan, Amy V

    2016-05-01

    Microbial transformation of n-alkanes in anaerobic ecosystems plays a pivotal role in biogeochemical carbon cycling and bioremediation, but the requisite genetic machinery is not well elucidated.Desulfatibacillum alkenivorans AK-01 utilizes n-alkanes (C13 to C18) and contains two genomic loci encoding alkylsuccinate synthase (ASS) gene clusters. ASS catalyzes alkane addition to fumarate to form methylalkylsuccinic acids. We hypothesized that the genes in the two clusters would be differentially expressed depending on the alkane substrate utilized for growth. RT-qPCR was used to investigate ass-gene expression across AK-01's known substrate range, and microarray-based transcriptomic analysis served to investigate whole-cell responses to growth on n-hexadecane versus hexadecanoate. RT-qPCR revealed induction of ass gene cluster 1 during growth on all tested alkane substrates, and the transcriptional start sites in cluster 1 were determined via 5'RACE. Induction of ass gene cluster 2 was not observed under the tested conditions. Transcriptomic analysis indicated that the upregulation of genes potentially involved in methylalkylsuccinate metabolism, including methylmalonyl-CoA mutase and a putative carboxyl transferase. These findings provide new directions for studying the transcriptional regulation of genes involved in alkane addition to fumarate, fumarate recycling and the processing of methylalkylsuccinates with regard to isolates, enrichment cultures and ecological datasets.

  16. Self efficacy for fruit, vegetable and water intakes: Expanded and abbreviated scales from item response modeling analyses

    Directory of Open Access Journals (Sweden)

    Cullen Karen W

    2010-03-01

    Full Text Available Abstract Objective To improve an existing measure of fruit and vegetable intake self efficacy by including items that varied on levels of difficulty, and testing a corresponding measure of water intake self efficacy. Design Cross sectional assessment. Items were modified to have easy, moderate and difficult levels of self efficacy. Classical test theory and item response modeling were applied. Setting One middle school at each of seven participating sites (Houston TX, Irvine CA, Philadelphia PA, Pittsburg PA, Portland OR, rural NC, and San Antonio TX. Subjects 714 6th grade students. Results Adding items to reflect level (low, medium, high of self efficacy for fruit and vegetable intake achieved scale reliability and validity comparable to existing scales, but the distribution of items across the latent variable did not improve. Selecting items from among clusters of items at similar levels of difficulty along the latent variable resulted in an abbreviated scale with psychometric characteristics comparable to the full scale, except for reliability. Conclusions The abbreviated scale can reduce participant burden. Additional research is necessary to generate items that better distribute across the latent variable. Additional items may need to tap confidence in overcoming more diverse barriers to dietary intake.

  17. Microarray analyses of inflammation response of human dermal fibroblasts to different strains of Borrelia burgdorferi sensu stricto.

    Directory of Open Access Journals (Sweden)

    Frédéric Schramm

    Full Text Available In Lyme borreliosis, the skin is the key site of bacterial inoculation by the infected tick, and of cutaneous manifestations, erythema migrans and acrodermatitis chronica atrophicans. We explored the role of fibroblasts, the resident cells of the dermis, in the development of the disease. Using microarray experiments, we compared the inflammation of fibroblasts induced by three strains of Borrelia burgdorferi sensu stricto isolated from different environments and stages of Lyme disease: N40 (tick, Pbre (erythema migrans and 1408 (acrodermatitis chronica atrophicans. The three strains exhibited a similar profile of inflammation with strong induction of chemokines (CXCL1 and IL-8 and IL-6 cytokine mainly involved in the chemoattraction of immune cells. Molecules such as TNF-alpha and NF-κB factors, metalloproteinases (MMP-1, -3 and -12 and superoxide dismutase (SOD2, also described in inflammatory and cellular events, were up-regulated. In addition, we showed that tick salivary gland extracts induce a cytotoxic effect on fibroblasts and that OspC, essential in the transmission of Borrelia to the vertebrate host, was not responsible for the secretion of inflammatory molecules by fibroblasts. Tick saliva components could facilitate the early transmission of the disease to the site of injury creating a feeding pit. Later in the development of the disease, Borrelia would intensively multiply in the skin and further disseminate to distant organs.

  18. Analyses of Numerical Responses and Main Life Parameters for Determining the Suppression of Amblyseius cucumeris on Panonychus citri

    Institute of Scientific and Technical Information of China (English)

    ZHANG Yan-xuan; LIN Jian-zhen; JI Jie; CHEN Xie; KANG Yu-mei

    2005-01-01

    In this paper, the numeral response and main parameters of experimental population life table were analyzed for determiningthe suppressing ability of Amblyseius cucumeris on Panonychus citri. The result showed that: (1) Under 21-31 ℃ and 1-9 prey densities/leaf fragment condition, the prey consumptions ofA. cucumeris increased with the temperature or prey density; (2) In 1:3 predator-prey ratio treatment, the suppression ofP. citri (Ro=34.0053; T=19.4369; t=3.8204) was rather weak, it was enhanced as the ratio over 5:30, and the populations ofP. citri in these treatments can be fully controlled within 4-5 days; (3) Under 25±1℃, 80-85% RH and 15L: 9D illumination conditions, the net reproductive rate, mean generation duration and the time for population double increase ofP. citri (Ro=34.0053; T=19.4369; t=3.8204) were higher than those ofA. cucumeris (Ro=21.8750; T=16.8943; t=3.7954). While the intrinsic rate of increase and finite rate of increase of the former (rm=0.1814; λ= 1.1989) were lower than those of the latter (rm=0.1826; λ= 1.2004). These results indicated that A. cucumeris is a desirable bio-control agent to suppress P. citri at lower population stage in citrus orchard.

  19. Colossal thermomagnetic response in chiral d-wave superconductor URu2Si2

    Science.gov (United States)

    Matsuda, Yuji

    The heavy-fermion compound URu2Si2 exhibits unconventional superconductivity at Tc = 1.45 K deep inside the so-called hidden order phase. An intriguing aspect is that this system has been suggested to be a candidate of a chiral d-wave superconductor, and possible Weyl-type topological superconducting states have been discussed recently. Here we report on the observation of a highly unusual Nernst signal due to the superconducting fluctuations above Tc. The Nernst coefficient is anomalously enhanced (by a factor of ~106) as compared with the theoretically expected value of the Gaussian fluctuations. This colossal Nernst effect intimately reflects the highly unusual superconducting state of URu2Si2. The results invoke possible chiral or Berry-phase fluctuations associated with the broken time-reversal symmetry of the superconducting order parameter. In collaboration with T. Yamashita, Y. Shimoyama, H. Sumiyoshi (Kyoto), S. Fujimoto (Osaka), T. Shibauchi (Tokyo), Y. Haga (JAEA), T. D. Matsuda (TMU) , Y. Onuki (Ryukyus), A. Levchenko (Wisconsin-Madison).

  20. Wave-induced response of a floating two-dimensional body with a moonpool

    Science.gov (United States)

    Fredriksen, Arnt G.; Kristiansen, Trygve; Faltinsen, Odd M.

    2015-01-01

    Regular wave-induced behaviour of a floating stationary two-dimensional body with a moonpool is studied. The focus is on resonant piston-mode motion in the moonpool and rigid-body motions. Dedicated two-dimensional experiments have been performed. Two numerical hybrid methods, which have previously been applied to related problems, are further developed. Both numerical methods couple potential and viscous flow. The semi-nonlinear hybrid method uses linear free-surface and body-boundary conditions. The other one uses fully nonlinear free-surface and body-boundary conditions. The harmonic polynomial cell method solves the Laplace equation in the potential flow domain, while the finite volume method solves the Navier–Stokes equations in the viscous flow domain near the body. Results from the two codes are compared with the experimental data. The nonlinear hybrid method compares well with the data, while certain discrepancies are observed for the semi-nonlinear method. In particular, the roll motion is over-predicted by the semi-nonlinear hybrid method. Error sources in the semi-nonlinear hybrid method are discussed. The moonpool strongly affects heave motions in a frequency range around the piston-mode resonance frequency of the moonpool. No resonant water motions occur in the moonpool at the piston-mode resonance frequency. Instead large moonpool motions occur at a heave natural frequency associated with small damping near the piston-mode resonance frequency. PMID:25512594

  1. Threshold response using modulated continuous wave illumination for multilayer 3D optical data storage

    Science.gov (United States)

    Saini, A.; Christenson, C. W.; Khattab, T. A.; Wang, R.; Twieg, R. J.; Singer, K. D.

    2017-01-01

    In order to achieve a high capacity 3D optical data storage medium, a nonlinear or threshold writing process is necessary to localize data in the axial dimension. To this end, commercial multilayer discs use thermal ablation of metal films or phase change materials to realize such a threshold process. This paper addresses a threshold writing mechanism relevant to recently reported fluorescence-based data storage in dye-doped co-extruded multilayer films. To gain understanding of the essential physics, single layer spun coat films were used so that the data is easily accessible by analytical techniques. Data were written by attenuating the fluorescence using nanosecond-range exposure times from a 488 nm continuous wave laser overlapping with the single photon absorption spectrum. The threshold writing process was studied over a range of exposure times and intensities, and with different fluorescent dyes. It was found that all of the dyes have a common temperature threshold where fluorescence begins to attenuate, and the physical nature of the thermal process was investigated.

  2. Kvalitative analyser ..

    DEFF Research Database (Denmark)

    Boolsen, Merete Watt

    bogen forklarer de fundamentale trin i forskningsprocessen og applikerer dem på udvalgte kvalitative analyser: indholdsanalyse, Grounded Theory, argumentationsanalyse og diskursanalyse......bogen forklarer de fundamentale trin i forskningsprocessen og applikerer dem på udvalgte kvalitative analyser: indholdsanalyse, Grounded Theory, argumentationsanalyse og diskursanalyse...

  3. Simulated austral winter response of the Hadley circulation and stationary Rossby wave propagation to a warming climate

    Science.gov (United States)

    Freitas, Ana C. V.; Frederiksen, Jorgen S.; O'Kane, Terence J.; Ambrizzi, Tércio

    2017-07-01

    Ensemble simulations, using both coupled ocean-atmosphere (AOGCM) and atmosphere only (AGCM) general circulation models, are employed to examine the austral winter response of the Hadley circulation (HC) and stationary Rossby wave propagation (SRW) to a warming climate. Changes in the strength and width of the HC are firstly examined in a set of runs with idealized sea surface temperature (SST) perturbations as boundary conditions in the AGCM. Strong and weak SST gradient experiments (SG and WG, respectively) simulate changes in the HC intensity, whereas narrow (5°S-5°N) and wide (30°S-30°N) SST warming experiments simulate changes in the HC width. To examine the combined impact of changes in the strength and width of the HC upon SRW propagation two AOGCM simulations using different scenarios of increasing carbon dioxide (CO2) concentrations are employed. We show that, in contrast to a wide SST warming, the atmospheric simulations with a narrow SST warming produce stronger and very zonally extended Rossby wave sources, leading to stronger and eastward shifted troughs and ridges. Simulations with SST anomalies, either in narrow or wide latitude bands only modify the intensity of the troughs and ridges. SST anomalies outside the narrow latitude band of 5°S-5°N do not significantly affect the spatial pattern of SRW propagation. AOGCM simulations with 1 %/year increasing CO2 concentrations or 4 times preindustrial CO2 levels reveal very similar SRW responses to the atmospheric only simulations with anomalously wider SST warming. Our results suggest that in a warmer climate, the changes in the strength and width of the HC act in concert to significantly alter SRW sources and propagation characteristics.

  4. Simulated austral winter response of the Hadley circulation and stationary Rossby wave propagation to a warming climate

    Science.gov (United States)

    Freitas, Ana C. V.; Frederiksen, Jorgen S.; O'Kane, Terence J.; Ambrizzi, Tércio

    2016-09-01

    Ensemble simulations, using both coupled ocean-atmosphere (AOGCM) and atmosphere only (AGCM) general circulation models, are employed to examine the austral winter response of the Hadley circulation (HC) and stationary Rossby wave propagation (SRW) to a warming climate. Changes in the strength and width of the HC are firstly examined in a set of runs with idealized sea surface temperature (SST) perturbations as boundary conditions in the AGCM. Strong and weak SST gradient experiments (SG and WG, respectively) simulate changes in the HC intensity, whereas narrow (5°S-5°N) and wide (30°S-30°N) SST warming experiments simulate changes in the HC width. To examine the combined impact of changes in the strength and width of the HC upon SRW propagation two AOGCM simulations using different scenarios of increasing carbon dioxide (CO2) concentrations are employed. We show that, in contrast to a wide SST warming, the atmospheric simulations with a narrow SST warming produce stronger and very zonally extended Rossby wave sources, leading to stronger and eastward shifted troughs and ridges. Simulations with SST anomalies, either in narrow or wide latitude bands only modify the intensity of the troughs and ridges. SST anomalies outside the narrow latitude band of 5°S-5°N do not significantly affect the spatial pattern of SRW propagation. AOGCM simulations with 1 %/year increasing CO2 concentrations or 4 times preindustrial CO2 levels reveal very similar SRW responses to the atmospheric only simulations with anomalously wider SST warming. Our results suggest that in a warmer climate, the changes in the strength and width of the HC act in concert to significantly alter SRW sources and propagation characteristics.

  5. Highly sensitive and ultrafast response surface acoustic wave humidity sensor based on electrospun polyaniline/poly(vinyl butyral) nanofibers.

    Science.gov (United States)

    Lin, Qianqian; Li, Yang; Yang, Mujie

    2012-10-20

    Polyaniline (PANi) composite nanofibers were deposited on surface acoustic wave (SAW) resonator with a central frequency of 433 MHz to construct humidity sensors. Electrospun nanofibers of poly(methyl methacrylate), poly(vinyl pyrrolidone), poly(ethylene oxide), poly(vinylidene fluoride), poly(vinyl butyral) (PVB) were characterized by scanning electron microscopy, and humidity response of corresponding SAW humidity sensors were investigated. The results indicated that PVB was suitable as a matrix to form nanofibers with PANi by electrospinning (ES). Electrospun PANi/PVB nanofibers exhibited a core-sheath structure as revealed by transmittance electron microscopy. Effects of ES collection time on humidity response of SAW sensor based on PANi/PVB nanofibers were examined at room temperature. The composite nanofiber sensor exhibited very high sensitivity of ~75kHz/%RH from 20 to 90%RH, ultrafast response (1s and 2s for humidification and desiccation, respectively) and good sensing linearity. Furthermore, the sensor could detect humidity as low as 0.5%RH, suggesting its potentials for low humidity detection. Attempts were done to explain the attractive humidity sensing performance of the sensor by considering conductivity, hydrophilicity, viscoelasticity and morphology of the polymer composite nanofibers. Copyright © 2012 Elsevier B.V. All rights reserved.

  6. Measurement of the I =1 /2 K π S -wave amplitude from Dalitz plot analyses of ηc→K K ¯π in two-photon interactions

    Science.gov (United States)

    Lees, J. P.; Poireau, V.; Tisserand, V.; Grauges, E.; Palano, A.; Eigen, G.; Brown, D. N.; Kolomensky, Yu. G.; Koch, H.; Schroeder, T.; Hearty, C.; Mattison, T. S.; McKenna, J. A.; So, R. Y.; Blinov, V. E.; Buzykaev, A. R.; Druzhinin, V. P.; Golubev, V. B.; Kravchenko, E. A.; Onuchin, A. P.; Serednyakov, S. I.; Skovpen, Yu. I.; Solodov, E. P.; Todyshev, K. Yu.; Lankford, A. J.; Gary, J. W.; Long, O.; Eisner, A. M.; Lockman, W. S.; Panduro Vazquez, W.; Chao, D. S.; Cheng, C. H.; Echenard, B.; Flood, K. T.; Hitlin, D. G.; Kim, J.; Miyashita, T. S.; Ongmongkolkul, P.; Porter, F. C.; Röhrken, M.; Huard, Z.; Meadows, B. T.; Pushpawela, B. G.; Sokoloff, M. D.; Sun, L.; Smith, J. G.; Wagner, S. R.; Bernard, D.; Verderi, M.; Bettoni, D.; Bozzi, C.; Calabrese, R.; Cibinetto, G.; Fioravanti, E.; Garzia, I.; Luppi, E.; Santoro, V.; Calcaterra, A.; de Sangro, R.; Finocchiaro, G.; Martellotti, S.; Patteri, P.; Peruzzi, I. M.; Piccolo, M.; Zallo, A.; Passaggio, S.; Patrignani, C.; Bhuyan, B.; Mallik, U.; Chen, C.; Cochran, J.; Prell, S.; Ahmed, H.; Pennington, M. R.; Gritsan, A. V.; Arnaud, N.; Davier, M.; Le Diberder, F.; Lutz, A. M.; Wormser, G.; Lange, D. J.; Wright, D. M.; Coleman, J. P.; Gabathuler, E.; Hutchcroft, D. E.; Payne, D. J.; Touramanis, C.; Bevan, A. J.; Di Lodovico, F.; Sacco, R.; Cowan, G.; Banerjee, Sw.; Brown, D. N.; Davis, C. L.; Denig, A. G.; Fritsch, M.; Gradl, W.; Griessinger, K.; Hafner, A.; Schubert, K. R.; Barlow, R. J.; Lafferty, G. D.; Cenci, R.; Jawahery, A.; Roberts, D. A.; Cowan, R.; Cheaib, R.; Robertson, S. H.; Dey, B.; Neri, N.; Palombo, F.; Cremaldi, L.; Godang, R.; Summers, D. J.; Taras, P.; De Nardo, G.; Sciacca, C.; Raven, G.; Jessop, C. P.; LoSecco, J. M.; Honscheid, K.; Kass, R.; Gaz, A.; Margoni, M.; Posocco, M.; Rotondo, M.; Simi, G.; Simonetto, F.; Stroili, R.; Akar, S.; Ben-Haim, E.; Bomben, M.; Bonneaud, G. R.; Calderini, G.; Chauveau, J.; Marchiori, G.; Ocariz, J.; Biasini, M.; Manoni, E.; Rossi, A.; Batignani, G.; Bettarini, S.; Carpinelli, M.; Casarosa, G.; Chrzaszcz, M.; Forti, F.; Giorgi, M. A.; Lusiani, A.; Oberhof, B.; Paoloni, E.; Rama, M.; Rizzo, G.; Walsh, J. J.; Smith, A. J. S.; Anulli, F.; Faccini, R.; Ferrarotto, F.; Ferroni, F.; Pilloni, A.; Piredda, G.; Bünger, C.; Dittrich, S.; Grünberg, O.; Heß, M.; Leddig, T.; Voß, C.; Waldi, R.; Adye, T.; Wilson, F. F.; Emery, S.; Hamel de Monchenault, G.; Vasseur, G.; Aston, D.; Cartaro, C.; Convery, M. R.; Dorfan, J.; Dunwoodie, W.; Ebert, M.; Field, R. C.; Fulsom, B. G.; Graham, M. T.; Hast, C.; Innes, W. R.; Kim, P.; Leith, D. W. G. S.; Luitz, S.; Luth, V.; MacFarlane, D. B.; Muller, D. R.; Neal, H.; Ratcliff, B. N.; Roodman, A.; Sullivan, M. K.; Va'vra, J.; Wisniewski, W. J.; Purohit, M. V.; Wilson, J. R.; Randle-Conde, A.; Sekula, S. J.; Bellis, M.; Burchat, P. R.; Puccio, E. M. T.; Alam, M. S.; Ernst, J. A.; Gorodeisky, R.; Guttman, N.; Peimer, D. R.; Soffer, A.; Spanier, S. M.; Ritchie, J. L.; Schwitters, R. F.; Izen, J. M.; Lou, X. C.; Bianchi, F.; De Mori, F.; Filippi, A.; Gamba, D.; Lanceri, L.; Vitale, L.; Martinez-Vidal, F.; Oyanguren, A.; Albert, J.; Beaulieu, A.; Bernlochner, F. U.; King, G. J.; Kowalewski, R.; Lueck, T.; Nugent, I. M.; Roney, J. M.; Tasneem, N.; Gershon, T. J.; Harrison, P. F.; Latham, T. E.; Prepost, R.; Wu, S. L.; BaBar Collaboration

    2016-01-01

    We study the processes γ γ →KS0K±π∓ and γ γ →K+K-π0 using a data sample of 519 fb-1 recorded with the BABAR detector operating at the SLAC PEP-II asymmetric-energy e+e- collider at center-of-mass energies at and near the Υ (n S ) (n =2 , 3, 4) resonances. We observe ηc decays to both final states and perform Dalitz plot analyses using a model-independent partial wave analysis technique. This allows a model-independent measurement of the mass-dependence of the I =1 /2 K π S -wave amplitude and phase. A comparison between the present measurement and those from previous experiments indicates similar behavior for the phase up to a mass of 1.5 GeV /c2. In contrast, the amplitudes show very marked differences. The data require the presence of a new a0(1950 ) resonance with parameters m =1931 ±14 ±22 MeV /c2 and Γ =271 ±22 ±29 MeV .

  7. Study on Short-term Variability of Ship Responses in Waves

    DEFF Research Database (Denmark)

    Iseki, Toshio; Nielsen, Ulrik Dam

    2014-01-01

    Short-term variability of ship responses is investigated from the view point of cross-spectrum analysis. In a steady state condition, it is well known that a certain length of sampled data are required for stable spectral analysis. However, the phase angle of the cross-spectra has not been discus...

  8. An ability approach to within-class curriculum differentiation using student response systems and Web 2.0 technologies: Analysing teachers’ responsiveness

    Directory of Open Access Journals (Sweden)

    Matt Bower

    2012-01-01

    Full Text Available This paper examines teacher responsiveness to an ability approach of within-class curriculum differentiation using technology. Teachers were guided through a series of four workshops designed to enhance their capacity to differentiate the curriculum using Web 2.0 technologies and Student Response Systems. Anderson & Krathwohl’s (2001 Taxonomy of Learning, Teaching and Assessing was used as a framework for the within-class ability differentiation. As a result of the project there was a discernable focusing of teachers’ conceptualisations of differentiation and its value. There were also improvements in teachers’ self-reported ability to differentiate the curriculum, ability to integrate technology into the classroom, and enjoyment of using technology. Considerable variance in teachers’ capacity to differentiate according to student ability using technology was observed, indicating that a differentiated approach to supporting teachers’ development in this area may be required.

  9. Analysis of the impact of the demand response RESIDENS field test on the customer load behaviour; Analyse des Einflusses vom Demand Response RESIDENS-Feldversuch auf das Kundenlastverhalten

    Energy Technology Data Exchange (ETDEWEB)

    Arnoldt, A.; Warweg, O.; Frenzel, S.; Bretschneider, P. [Fraunhofer IOSB, Ilmenau (Germany). Answendungszentrum Systemtechnik; Werner, M.

    2012-07-01

    The project RESIDENS investigates interactions between the technical electrical grid system and the private end customers through demand response, based on interdisciplinary methodology. December 2010 started the field test investigating the customer behavior on time varying tariffs. Significant load displacements between the trail group and the reference group or the standard load profile of the BDEW (former VDEW) can be detected within the preliminary investigations as well as the latest ones. (orig.)

  10. Short-term pressure and temperature MSLB response analyses for large dry containment of the Maanshan nuclear power station

    Energy Technology Data Exchange (ETDEWEB)

    Dai, Liang-Che, E-mail: lcdai@iner.gov.tw; Chen, Yen-Shu; Yuann, Yng-Ruey

    2014-12-15

    Highlights: • The GOTHIC code is used for the PWR dry containment pressure and temperature analysis. • Boundary conditions are hot standby and 102% power main steam line break accidents. • Containment pressure and temperature responses of GOTHIC are similar with FSAR. • The capability of the developed model to perform licensing calculation is assessed. - Abstract: Units 1 and 2 of the Maanshan nuclear power station are the typical Westinghouse three-loop PWR (pressurized water reactor) with large dry containments. In this study, the containment analysis program GOTHIC is adopted for the dry containment pressure and temperature analysis. Free air space and sump of the PWR dry containment are individually modeled as control volumes. The containment spray system and fan cooler unit are also considered in the GOTHIC model. The blowdown mass and energy data of the main steam line break (hot standby condition and various reactor thermal power levels) are tabulated in the Maanshan Final Safety Analysis Report (FSAR) 6.2 which could be used as the boundary conditions for the containment model. The calculated containment pressure and temperature behaviors of the selected cases are in good agreement with the FSAR results. In this study, hot standby and 102% reactor thermal power main steam line break accidents are selected. The calculated peak containment pressure is 323.50 kPag (46.92 psig) for hot standby MSLB, which is a little higher than the FSAR value of 311.92 kPag (45.24 psig). But it is still below the design value of 413.69 kPag (60 psig). The calculated peak vapor temperature inside the containment is 187.0 °C (368.59 F) for 102% reactor thermal power MSLB, which is lower than the FSAR result of 194.42 °C (381.95 F). The effects of the containment spray system and fan cooler units could be clearly observed in the GOTHIC analysis. The calculated containment pressure and temperature behaviors of the selected cases are in good agreement with the FSAR

  11. Analyses between Reproductive Behaviour, Genetic Diversity and Pythium Responsiveness in Zingiber spp. reveal an adaptive significance for hemiclonality

    Directory of Open Access Journals (Sweden)

    Geethu Elizabath Thomas

    2016-12-01

    Full Text Available AbstractMode of reproduction is generally considered to have long-range evolutionary implications on population survival. Because sexual reproduction produces genetically diverse genotypes, this mode of reproduction is predicted to positively influence the success potential of offspring in evolutionary arms race with parasites (Red queen whereas, without segregation and recombination, the obligate asexual multiplication may push a species into extinction due to the steady accumulation of deleterious mutations (Muller’s ratchet. However, the extent of linearity between reproductive strategies, genetic diversity and population fitness, and the contributions of different breeding strategies to population fitness are yet to be understood clearly. Genus Zingiber belonging to the pan-tropic family Zingiberaceae represents a good system to study contributions of different breeding behaviour on genetic diversity and population fitness, as this genus comprises species with contrasting breeding systems. In this study, we analyzed breeding behaviour, amplified fragment length polymorphism (AFLP diversity and response to the soft-rot pathogen Pythium aphanidermatum in 18 natural populations of three wild Zingiber spp.: Z. neesanum, Z. nimmonii and Z. zerumbet, together with the obligately asexual cultivated congener, ginger (Z. officinale. Ginger showed an exceptionally narrow genetic base, and adding to this, all the tested cultivars were uniformly susceptible to soft-rot. Concordant with the postulates of Muller’s ratchet, the background selection may be continuously pushing ginger into the ancestral state, rendering it inefficient in host-pathogen coevolution. Z. neesanum and Z. nimmonii populations were sexual and genetically diverse; however, contrary to Red Queen expectations, the populations were highly susceptible to soft-rot. Z. zerumbet showed a hemiclonal breeding behaviour. The populations inhabiting forest understory were large and

  12. Coastal erosion in response to wave dynamics operative in Sagar Island, Sundarban delta, India

    Institute of Scientific and Technical Information of China (English)

    Barendra PURKAIT

    2009-01-01

    Coastal erosion at Sagar Island of Sunderban delta, India, has been critically studied. The area is in the subtropical humid region. There are mainly three seasons viz: winter, summer and the monsoon. Different wave dynamic parameters were measured from theodolite observations with leveling staff and measuring gauges during lunar days at two sections of the western and eastern parts of the coastal zone during post-and pre-monsoons. A comparative study was made on the erosion/depositional pattern between the two sections in relation to different hydrodynamic parameters prevailing in these two sections. Plane table mapping was carried out to demarcate the different geomorphic units. The marine coastal landforms show dune ridges with intervening flats bordered by gently sloping beach on one side and a flat beach on the other side. The western part of the beach is mainly sandy; whereas the eastern part is silty and clayey with mud bank remnants. Actual field measurements indicate that the coastal dune belt has retreated to the order by about 20 m since 1985. The eastern part of the beach has lowered by about 2 m since 1985 and the western part was raised almost to the same tune. It is observed that accretion in the western and central parts of the beach took place; whereas severe erosion in the eastern part made the beach very narrow with remnants of mud banks and tree roots. Frequent embankment failures, submergence and flooding, beach erosion and siltation at jetties and navigational channels, cyclones and storm surges made this area increasingly vulnerable.

  13. Acceleration Response Mode Decomposition for Quantifying Wave Impact Load in High-Speed Planing Craft

    Science.gov (United States)

    2014-04-01

    valid OMB control number. 1. REPORT DATE 17 APR 2014 2. REPORT TYPE Final 3. DATES COVERED - 4. TITLE AND SUBTITLE ACCELERATION RESPONSE MODE...display a currently valid OMB control number. PLEASE DO NOT RETURN YOUR FORM TO THE ABOVE ADDRESS. 1. REPORT DATE (DD/MM/YY) 17-04-2014 2. REPORT...Science and Engineering ( NISE ) Section 219 research and development program. Acknowledgements The authors would like to thank Dr. Jack L. Price

  14. The transient response of a quantum wave to an instantaneous potential step switching

    Energy Technology Data Exchange (ETDEWEB)

    Delgado, F [Departamento de Quimica-Fisica, Universidad del Pais Vasco, Apdo 644, 48080 Bilbao (Spain); Cruz, H [Departamento de Fisica Basica, Universidad de La Laguna (Spain); Muga, J G [Departamento de Quimica-Fisica, Universidad del Pais Vasco, Apdo 644, 48080 Bilbao (Spain)

    2002-12-06

    The transient response of a stationary state of a quantum particle in a step potential to an instantaneous change in the step height (a simplified model for a sudden bias switch in an electronic semiconductor device) is solved exactly by means of a semianalytical expression. The characteristic times for the transient process up to the new stationary state are identified. A comparison is made between the exact results and an approximate method.

  15. Estimation of S-wave site response in and around Delhi region from weak motion data

    Indian Academy of Sciences (India)

    S K Nath; P Sengupta; S K Srivastav; S N Bhattacharya; R S Dattatrayam; R Prakash; H V Gupta

    2003-09-01

    Site response in and around Delhi is studied using digital seismograms recorded by a thirteen-station VSAT-based 24-bit digital Delhi telemetry network of the India Meteorological Department. Nine local (l ≥ 2.3) and nine regional (l ≥ 3.9) earthquakes are selected for the estimation of site amplification factor using the classical standard spectral ratio for regional events (Ridge Delhi Observatory being the reference station), normalized standard spectral ratio for local events, horizontal-to-vertical spectral ratio or receiver function and the generalized inversion techniques in the frequency range of 0.5 to 7.5 Hz. Site response curves at all the thirteen stations exhibit station to station variation of the site amplification factor reflecting the changes in geologic/geotectonic/soil conditions. A comparison of the site response values obtained by the generalized inversion with those computed using receiver function technique shows a large scatter even though the pattern of the curves remain more or less similar. However, the site effects computed by generalized inversion and standard spectral ratio exhibit a good 1:1 correspondence. The peaks yielded by all the methods have been observed to occur at the same frequencies. It is evident that the softer fluvial deposits of the newer alluvium of the east Yamuna sector show steeper site amplification gradient at lower frequencies, while the greater Delhi experiences moderate site amplification. The variation of site response corroborates the abrupt changes in intensity from one location to another due to local site condition.

  16. Short-Wave Diathermy Pretreatment and Inflammatory Myokine Response After High-Intensity Eccentric Exercise.

    Science.gov (United States)

    Vardiman, John P; Moodie, Nicole; Siedlik, Jacob A; Kudrna, Rebecca A; Graham, Zachary; Gallagher, Philip

    2015-06-01

    Various modalities have been used to pretreat skeletal muscle to attenuate inflammation. To determine the effects of short-wave diathermy (SWD) preheating treatment on inflammation and stress markers after eccentric exercise. Controlled laboratory study. University laboratory setting. Fifteen male (age = 22 ± 4.9 years, height = 179.75 ± 9.56 cm, mass = 82.22 ± 12.67 kg) college-aged students. Seven participants were selected randomly to receive 40 minutes of SWD heat treatment (HT), and 8 participants served as the control (CON) group and rested without SWD. Both groups completed 7 sets of 10 repetitions of a high-intensity eccentric exercise protocol (EEP) at 120% of the 1-repetition maximum (1-RM) leg extension. We biopsied muscles on days 1, 3 (24 hours post-EEP), and 4 (48 hours post-EEP) and collected blood samples on days 1, 2 (4 hours post-EEP), 3, and 4. We determined 1-RM on day 2 (24 hours post-SWD) and measured 1-RM on days 3 and 4. We analyzed the muscle samples for interleukin 6 (IL-6), tumor necrosis factor α, and heat shock protein 70 and the blood for serum creatine kinase. We found a group × time interaction for intramuscular IL-6 levels after SWD (F2,26 = 7.13, P = .003). The IL-6 decreased in HT (F1,6 = 17.8, P = .006), whereas CON showed no change (P > .05). We found a group × time interaction for tumor necrosis factor α levels (F2,26 = 3.71, P = .04), which increased in CON (F2,14 = 7.16, P = .007), but saw no changes for HT (P > .05). No group × time interactions were noted for 1-RM, heat shock protein 70, or creatine kinase (P > .05). The SWD preheating treatment provided a treatment effect for intramuscular inflammatory myokines induced through high-intensity eccentric exercise but did not affect other factors associated with intense exercise and inflammation.

  17. Molecular dynamic study of Shock wave response of bulk amorphous polyvinyl chloride: effect of chain length and force field

    Science.gov (United States)

    Neogi, Anupam; Mitra, Nilanjan

    2015-06-01

    Atomistic molecular dynamics in conjunction with multi-scale shock technique is utilized to investigate shock wave response of bulk amorphous polyvinyl chloride. Dependence of chain length on physical and mechanical behaviour of polymeric material at ambient condition of temperature and pressure are well known but unknown for extreme conditions. Non-reactive force fields PCFF, COMPASS and PCFF+ were used to determine applicability of the force field for the study of the material subjected to shock loads. Several samples of PVC with various chain lengths were subjected to a range of shock compression from 1.5-10.0 km/s. Even though dependence of chain length was observed for lower shock strengths but was not for intense shock loads. The principle Hugoniot points, calculated by applying hydrostatic Rankine-Hugoniot equations and as well as multi-scale shock technique, were compared against LASL experimental shock data, demonstrating superior performance of PCFF+ force-field over PCFF and COMPASS. Shock induced melting characteristic and vibrational spectroscopic study were conducted and compared with experimental data to observe differences in response with relation to different force fields, chain length of the material for different shock intensities.

  18. Probing the momentum-dependent response of the charge density wave phase in TbTe{sub 3} by ultrafast time- and angle-resolved photoemission

    Energy Technology Data Exchange (ETDEWEB)

    Kirchmann, P.S. [Department of Applied Physics, Stanford University, Stanford, CA (United States); Fachbereich Physik, Freie Universitaet Berlin (Germany); Schmitt, F.T.; Moore, R.G.; Chu, J.H.; Ru, N.; Fisher, I.R.; Shen, Z.X. [Department of Applied Physics, Stanford University, Stanford, CA (United States); Bovensiepen, U. [Fachbereich Physik, Freie Universitaet Berlin (Germany); Universitaet Duisburg-Essen, Institut fuer Experimentelle Physik, Duisburg (Germany); Rettig, L.; Krenz, M. [Fachbereich Physik, Freie Universitaet Berlin (Germany); Perfetti, L. [Fachbereich Physik, Freie Universitaet Berlin (Germany); Ecole Polytechnique, Palaiseau (France); Wolf, M. [Fachbereich Physik, Freie Universitaet Berlin (Germany); Fritz-Haber-Institut der Max-Planck-Gesellschaft, Berlin (Germany)

    2010-07-01

    Charge density wave (CDW) systems such as TbTe{sub 3} offer fascinating options for studying the correlation of electrons and the lattice. We investigate the ultrafast response of the charge density wave (CDW) phase in TbTe{sub 3} after femtosecond IR excitation using time- and angle-resolved photoemission. The time-dependent photoemission intensity at the Fermi level yields a characteristic time for the closing of the CDW bandgap. With increasing laser fluence the bandgap closes faster, pointing to an increasing slope of the excited potential energy surface. As function of electron momentum the amplitude of the response increases strongly at the position of the Fermi wave vector k{sub F}. These results vividly demonstrate that the CDW system is most susceptible to electronic excitations near k{sub F} and that these electronic perturbations drive collective excitations of the coupled electron-lattice system.

  19. Friction drive of an SAW motor. Part II: analyses.

    Science.gov (United States)

    Shigematsu, Takashi; Kurosawa, Minoru Kuribayashi

    2008-09-01

    The mechanics of the friction drive of a surface acoustic wave motor were investigated by means of contact mechanics theory. As a means to control the contact condition, the motor's slider had projections on its frictional surface. Assuming the projection was a rigid circular punch and the slider body was an elastic half-space allowed application of contact mechanics formulae to the analyses of the friction drive. Because the projection contacted the Rayleigh wave vibration, the projection's responses were considered dynamic; thus, the dynamics were also analyzed in the same framework of contact mechanics formulae. Moreover, the analyses were applied to measurements of the projection's displacement to examine the detailed mechanics during the friction drive. We calculated the contact/frictional forces based on the measurement and indicated the necessity of further investigation of the surface acoustic wave motor's friction drive, because the usual friction law was unable to explain the measurement.

  20. Integration of Genome-Wide Computation DRE Search, AhR ChIP-chip and Gene Expression Analyses of TCDD-Elicited Responses in the Mouse Liver

    Directory of Open Access Journals (Sweden)

    Matthews Jason

    2011-07-01

    Full Text Available Abstract Background The aryl hydrocarbon receptor (AhR is a ligand-activated transcription factor (TF that mediates responses to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD. Integration of TCDD-induced genome-wide AhR enrichment, differential gene expression and computational dioxin response element (DRE analyses further elucidate the hepatic AhR regulatory network. Results Global ChIP-chip and gene expression analyses were performed on hepatic tissue from immature ovariectomized mice orally gavaged with 30 μg/kg TCDD. ChIP-chip analysis identified 14,446 and 974 AhR enriched regions (1% false discovery rate at 2 and 24 hrs, respectively. Enrichment density was greatest in the proximal promoter, and more specifically, within ± 1.5 kb of a transcriptional start site (TSS. AhR enrichment also occurred distal to a TSS (e.g. intergenic DNA and 3' UTR, extending the potential gene expression regulatory roles of the AhR. Although TF binding site analyses identified over-represented DRE sequences within enriched regions, approximately 50% of all AhR enriched regions lacked a DRE core (5'-GCGTG-3'. Microarray analysis identified 1,896 number of TCDD-responsive genes (|fold change| ≥ 1.5, P1(t > 0.999. Integrating this gene expression data with our ChIP-chip and DRE analyses only identified 625 differentially expressed genes that involved an AhR interaction at a DRE. Functional annotation analysis of differentially regulated genes associated with AhR enrichment identified overrepresented processes related to fatty acid and lipid metabolism and transport, and xenobiotic metabolism, which are consistent with TCDD-elicited steatosis in the mouse liver. Conclusions Details of the AhR regulatory network have been expanded to include AhR-DNA interactions within intragenic and intergenic genomic regions. Moreover, the AhR can interact with DNA independent of a DRE core suggesting there are alternative mechanisms of AhR-mediated gene regulation.

  1. Gene expression profiling and phenotype analyses of S. cerevisiae in response to changing copper reveals six genes with new roles in copper and iron metabolism.

    Science.gov (United States)

    van Bakel, Harm; Strengman, Eric; Wijmenga, Cisca; Holstege, Frank C P

    2005-08-11

    Exhaustive microarray time course analyses of Saccharomyces cerevisiae during copper starvation and copper excess reveal new aspects of metal-induced gene regulation. Aside from identifying targets of established copper- and iron-responsive transcription factors, we find that genes encoding mitochondrial proteins are downregulated and that copper-independent iron transport genes are preferentially upregulated, both during prolonged copper deprivation. The experiments also suggest the presence of a small regulatory iron pool that links copper and iron responses. One hundred twenty-eight genes with putative roles in metal metabolism were further investigated by several systematic phenotype screens. Of the novel phenotypes uncovered, hsp12-Delta and arn1-Delta display increased sensitivity to copper, cyc1-Delta and crr1-Delta show resistance to high copper, vma13-Delta exhibits increased sensitivity to iron deprivation, and pep12-Delta results in reduced growth in high copper and low iron. Besides revealing new components of eukaryotic metal trafficking pathways, the results underscore the previously determined intimate links between iron and copper metabolism and mitochondrial and vacuolar function in metal trafficking. The analyses further suggest that copper starvation can specifically lead to downregulation of respiratory function to preserve iron and copper for other cellular processes.

  2. Benthic reef primary production in response to large amplitude internal waves at the Similan Islands (Andaman Sea, Thailand)

    KAUST Repository

    Jantzen, Carin

    2013-11-29

    Coral reefs are facing rapidly changing environments, but implications for reef ecosystem functioning and important services, such as productivity, are difficult to predict. Comparative investigations on coral reefs that are naturally exposed to differing environmental settings can provide essential information in this context. One prevalent phenomenon regularly introducing alterations in water chemistry into coral reefs are internal waves. This study therefore investigates the effect of large amplitude internal waves (LAIW) on primary productivity in coral reefs at the Similan Islands (Andaman Sea, Thailand). The LAIW-exposed west sides of the islands are subjected to sudden drops in water temperature accompanied by enhanced inorganic nutrient concentrations compared to the sheltered east. At the central island, Ko Miang, east and west reefs are only few hundred meters apart, but feature pronounced differences. On the west lower live coral cover (-38%) coincides with higher turf algae cover (+64%) and growth (+54%) compared to the east side. Turf algae and the reef sand-associated microphytobenthos displayed similar chlorophyll a contents on both island sides, but under LAIW exposure, turf algae exhibited higher net photosynthesis (+23%), whereas the microphytobenthos displayed reduced net and gross photosynthesis (-19% and -26%, respectively) accompanied by lower respiration (-42%). In contrast, the predominant coral Porites lutea showed higher chlorophyll a tissues contents (+42%) on the LAIW-exposed west in response to lower light availability and higher inorganic nutrient concentrations, but net photosynthesis was comparable for both sides. Turf algae were the major primary producers on the west side, whereas microphytobenthos dominated on the east. The overall primary production rate (comprising all main benthic primary producers) was similar on both island sides, which indicates high primary production variability under different environmental conditions.

  3. Benthic reef primary production in response to large amplitude internal waves at the Similan Islands (Andaman Sea, Thailand).

    Science.gov (United States)

    Jantzen, Carin; Schmidt, Gertraud M; Wild, Christian; Roder, Cornelia; Khokiattiwong, Somkiat; Richter, Claudio

    2013-01-01

    Coral reefs are facing rapidly changing environments, but implications for reef ecosystem functioning and important services, such as productivity, are difficult to predict. Comparative investigations on coral reefs that are naturally exposed to differing environmental settings can provide essential information in this context. One prevalent phenomenon regularly introducing alterations in water chemistry into coral reefs are internal waves. This study therefore investigates the effect of large amplitude internal waves (LAIW) on primary productivity in coral reefs at the Similan Islands (Andaman Sea, Thailand). The LAIW-exposed west sides of the islands are subjected to sudden drops in water temperature accompanied by enhanced inorganic nutrient concentrations compared to the sheltered east. At the central island, Ko Miang, east and west reefs are only few hundred meters apart, but feature pronounced differences. On the west lower live coral cover (-38 %) coincides with higher turf algae cover (+64 %) and growth (+54 %) compared to the east side. Turf algae and the reef sand-associated microphytobenthos displayed similar chlorophyll a contents on both island sides, but under LAIW exposure, turf algae exhibited higher net photosynthesis (+23 %), whereas the microphytobenthos displayed reduced net and gross photosynthesis (-19 % and -26 %, respectively) accompanied by lower respiration (-42 %). In contrast, the predominant coral Porites lutea showed higher chlorophyll a tissues contents (+42 %) on the LAIW-exposed west in response to lower light availability and higher inorganic nutrient concentrations, but net photosynthesis was comparable for both sides. Turf algae were the major primary producers on the west side, whereas microphytobenthos dominated on the east. The overall primary production rate (comprising all main benthic primary producers) was similar on both island sides, which indicates high primary production variability under different environmental

  4. On the use of the fictitious wave steepness and related surf-similarity parameters in methods that describe the hydraulic and structural response to waves

    NARCIS (Netherlands)

    Heineke, D.; Verhagen, H.J.

    2007-01-01

    To assess the hydraulic performance of coastal structures - viz. wave run-up, overtopping and reflection - and to evaluate the stability of the armour layers, use is made of the dimensionless surf similarity parameter, as introduced by Battjes (1974). The front side slope of the structure and the wa

  5. On the use of the fictitious wave steepness and related surf-similarity parameters in methods that describe the hydraulic and structural response to waves

    NARCIS (Netherlands)

    Heineke, D.; Verhagen, H.J.

    2007-01-01

    To assess the hydraulic performance of coastal structures - viz. wave run-up, overtopping and reflection - and to evaluate the stability of the armour layers, use is made of the dimensionless surf similarity parameter, as introduced by Battjes (1974). The front side slope of the structure and the

  6. Biomechanical modeling for the response of human thorax to blast waves

    Science.gov (United States)

    Zhou, Jie; Tao, Gang

    2015-08-01

    A simplified finite element model of a human thorax had been developed for probing into the mechanical response in simple and complex blast environments. The human thorax model was first created by CT images with blast loading applied via a coupled arbitrary Lagrangian-Eulerian method, allowing for a variety of loads to be considered. The goal is to analyze the maximum stress distributions of lung tissue and peak inward thorax wall velocity and to know the possible regions and levels of lung injury. In parallel, a mathematical model has been modified from the Lobdell model to investigate the detailed percentage of lung injury at each level. The blast loadings around the human thorax were obtained from the finite element model, and were then applied in the mathematical model as the boundary conditions to predict the normalized work of the human thorax lung. The present results are found in agreement with the modified Bowen curves and the results predicted by Axelsson's model.

  7. Multi-Wave Prospective Examination of the Stress-Reactivity Extension of Response Styles Theory of Depression in High-Risk Children and Early Adolescents

    Science.gov (United States)

    Abela, John R. Z.; Hankin, Benjamin L.; Sheshko, Dana M.; Fishman, Michael B.; Stolow, Darren

    2012-01-01

    The current study tested the stress-reactivity extension of response styles theory of depression (Nolen-Hoeksema "Journal of Abnormal Psychology" 100:569-582, 1991) in a sample of high-risk children and early adolescents from a vulnerability-stress perspective using a multi-wave longitudinal design. In addition, we examined whether obtained…

  8. Screened Raman response in two-dimensional d(x2-y2)-wave superconductors: Relative intensities in different symmetry channels

    DEFF Research Database (Denmark)

    Wenger, F.; Käll, M.

    1997-01-01

    We analyze the Raman-scattering response in a two-dimensional d(x2-y2)-wave superconductor and point out a strong suppression of relative intensity in the screened A(1g) channel compared to the B-1g channel for a generic tight-binding model. This is in contrast with the observed behavior in high...

  9. Estimation of shallow S-wave velocity structure and site response characteristics by microtremor array measurements in Tekirdag region, NW Turkey

    Science.gov (United States)

    Karagoz, Ozlem; Chimoto, Kosuke; Citak, Seckin; Ozel, Oguz; Yamanaka, Hiroaki; Hatayama, Ken

    2015-11-01

    In this study, we aimed to explore the S-wave velocity structure of shallow soils using microtremors in order to estimate site responses in Tekirdag and surrounding areas (NW Turkey). We collected microtremor array data at 44 sites in Tekirdag, Marmara Ereglisi, Corlu, and Muratlı. The phase velocities of Rayleigh waves were estimated from the microtremor data using a Spatial Autocorrelation method. Then, we applied a hybrid genetic simulated annealing algorithm to obtain a 1D S-wave velocity structure at each site. Comparison between the horizontal-to-vertical ratio of microtremors and computed ellipticities of the fundamental mode Rayleigh waves showed good agreement with validation models. The depth of the engineering bedrock changed from 20 to 50 m in the Tekirdag city center and along the coastline with a velocity range of 700-930 m/s, and it ranged between 10 and 65 m in Marmara Ereglisi. The average S-wave velocity of the engineering bedrock was 780 m/s in the region. We obtained average S-wave velocities in the upper 30 m to compare site amplifications. Empirical relationships between the AVs30, the site amplifications, and also average topographic slopes were established for use in future site effects microzonation studies in the region.

  10. The electromagnetic response of human skin in the millimetre and submillimetre wave range

    Energy Technology Data Exchange (ETDEWEB)

    Feldman, Yuri; Puzenko, Alexander; Ben Ishai, Paul; Caduff, Andreas; Davidovich, Issak; Sakran, Fadi; Agranat, Aharon J [Department of Applied Physics, Hebrew University of Jerusalem, Givat Ram, 91904, Jerusalem (Israel)], E-mail: yurif@vms.huji.ac.il

    2009-06-07

    Recent studies of the minute morphology of the skin by optical coherence tomography revealed that the sweat ducts in human skin are helically shaped tubes, filled with a conductive aqueous solution. This, together with the fact that the dielectric permittivity of the dermis is higher than that of the epidermis, brings forward the supposition that as electromagnetic entities, the sweat ducts could be regarded as low Q helical antennas. The implications of this statement were further investigated by electromagnetic simulation and experiment of the in vivo reflectivity of the skin of subjects under varying physiological conditions (Feldman et al 2008 Phys. Rev. Lett. 100 128102). The simulation and experimental results are in a good agreement and both demonstrate that sweat ducts in the skin could indeed behave as low Q antennas. Thus, the skin spectral response in the sub-Terahertz region is governed by the level of activity of the perspiration system and shows the minimum of reflectivity at some frequencies in the frequency band of 75-110 GHz. It is also correlated to physiological stress as manifested by the pulse rate and the systolic blood pressure. As such, it has the potential to become the underlying principle for remote sensing of the physiological parameters and the mental state of the examined subject.

  11. The electromagnetic response of human skin in the millimetre and submillimetre wave range.

    Science.gov (United States)

    Feldman, Yuri; Puzenko, Alexander; Ben Ishai, Paul; Caduff, Andreas; Davidovich, Issak; Sakran, Fadi; Agranat, Aharon J

    2009-06-07

    Recent studies of the minute morphology of the skin by optical coherence tomography revealed that the sweat ducts in human skin are helically shaped tubes, filled with a conductive aqueous solution. This, together with the fact that the dielectric permittivity of the dermis is higher than that of the epidermis, brings forward the supposition that as electromagnetic entities, the sweat ducts could be regarded as low Q helical antennas. The implications of this statement were further investigated by electromagnetic simulation and experiment of the in vivo reflectivity of the skin of subjects under varying physiological conditions (Feldman et al 2008 Phys. Rev. Lett. 100 128102). The simulation and experimental results are in a good agreement and both demonstrate that sweat ducts in the skin could indeed behave as low Q antennas. Thus, the skin spectral response in the sub-Terahertz region is governed by the level of activity of the perspiration system and shows the minimum of reflectivity at some frequencies in the frequency band of 75-110 GHz. It is also correlated to physiological stress as manifested by the pulse rate and the systolic blood pressure. As such, it has the potential to become the underlying principle for remote sensing of the physiological parameters and the mental state of the examined subject.

  12. Roadway dynamic response analysis under mining rockburst condition

    Institute of Scientific and Technical Information of China (English)

    LI Chun-rui; QI Qing-xin; PAN Jun-feng; LAN Hang

    2009-01-01

    In order to determine how a roadway withstands a momentum wave and de-termine the extent of damage to rock surrounding the roadway under different force wave peak impacts, the roadway dynamic response state was analysed using numerical simula-tion method. The roadway's critical peak force wave and fracture region under dynamic wave action were put forward. It is concluded that the method has practical value to road-way support and rockburst prevention.

  13. Propagation of elastic waves in DNA

    Directory of Open Access Journals (Sweden)

    Sunil Mukherjee

    1983-01-01

    Full Text Available The mathematical analyses of longitudinal and torsional elastic waves transmitted along DNA molecule undergoing Brownian motion in solution are presented. Longitudinal vibrations in DNA are shown to be responsible for drug intercalation and breathing. The near neighbor exclusion mode of drug intercalation is explained. Torsional oscillations in DNA are shown to be responsible for conformation transitions from a right handed to a left handed form, depending on sequence specificity in high salt concentration.

  14. Numerical Simulation on Seismic Response of the Filled Joint under High Amplitude Stress Waves Using Finite-Discrete Element Method (FDEM

    Directory of Open Access Journals (Sweden)

    Xiaolin Huang

    2016-12-01

    Full Text Available This paper numerically investigates the seismic response of the filled joint under high amplitude stress waves using the combined finite-discrete element method (FDEM. A thin layer of independent polygonal particles are used to simulate the joint fillings. Each particle is meshed using the Delaunay triangulation scheme and can be crushed when the load exceeds its strength. The propagation of the 1D longitude wave through a single filled joint is studied, considering the influences of the joint thickness and the characteristics of the incident wave, such as the amplitude and frequency. The results show that the filled particles under high amplitude stress waves mainly experience three deformation stages: (i initial compaction stage; (ii crushing stage; and (iii crushing and compaction stage. In the initial compaction stage and crushing and compaction stage, compaction dominates the mechanical behavior of the joint, and the particle area distribution curve varies little. In these stages, the transmission coefficient increases with the increase of the amplitude, i.e., peak particle velocity (PPV, of the incident wave. On the other hand, in the crushing stage, particle crushing plays the dominant role. The particle size distribution curve changes abruptly with the PPV due to the fragments created by the crushing process. This process consumes part of wave energy and reduces the stiffness of the filled joint. The transmission coefficient decreases with increasing PPV in this stage because of the increased amount of energy consumed by crushing. Moreover, with the increase of the frequency of the incident wave, the transmission coefficient decreases and fewer particles can be crushed. Under the same incident wave, the transmission coefficient decreases when the filled thickness increases and the filled particles become more difficult to be crushed.

  15. Examining the response of needle carbohydrates from Siberian larch trees to climate using compound-specific δ(13) C and concentration analyses.

    Science.gov (United States)

    Rinne, K T; Saurer, M; Kirdyanov, A V; Bryukhanova, M V; Prokushkin, A S; Churakova Sidorova, O V; Siegwolf, R T W

    2015-11-01

    Little is known about the dynamics of concentrations and carbon isotope ratios of individual carbohydrates in leaves in response to climatic and physiological factors. Improved knowledge of the isotopic ratio in sugars will enhance our understanding of the tree ring isotope ratio and will help to decipher environmental conditions in retrospect more reliably. Carbohydrate samples from larch (Larix gmelinii) needles of two sites in the continuous permafrost zone of Siberia with differing growth conditions were analysed with the Compound-Specific Isotope Analysis (CSIA). We compared concentrations and carbon isotope values (δ(13) C) of sucrose, fructose, glucose and pinitol combined with phenological data. The results for the variability of the needle carbohydrates show high dynamics with distinct seasonal characteristics between and within the studied years with a clear link to the climatic conditions, particularly vapour pressure deficit. Compound-specific differences in δ(13) C values as a response to climate were detected. The δ(13) C of pinitol, which contributes up to 50% of total soluble carbohydrates, was almost invariant during the whole growing season. Our study provides the first in-depth characterization of compound-specific needle carbohydrate isotope variability, identifies involved mechanisms and shows the potential of such results for linking tree physiological responses to different climatic conditions.

  16. Modelling the optical response of human retinal photoreceptors to plane wave illumination with the finite integration technique

    Science.gov (United States)

    Akhlagh Moayed, Alireza; Dang, Shannon; Ramahi, Omar M.; Bizheva, Kostadinka K.

    2009-02-01

    The early stages of ocular diseases such as Diabetic Retinopathy are manifested by morphological changes in retinal tissue occurring on cellular level. Therefore, a number of ophthalmic diseases can be diagnosed at an early stage by detecting spatial and temporal variations in the scattering profile of retinal tissue. It was recently demonstrated that, OCT can be used to probe the functional response of retinal photoreceptors to external light stimulation [1]-[3]. fUHROCT measures localized differential changes in the retina reflectivity over time resulting from external light stimulation of the retina. Currently the origins of the observed reflectivity changes are not well understood. However, due to the complex nature of retinal physiology using purely experimental approaches in this case is problematic. For example fUHROCT is sensitive to small changes in the refractive index of biological tissue which as demonstrated previously, can result from a number of processes such as membrane hyperpolarization, osmotic swelling, metabolic changes, etc. In this paper, we present a computational model of interaction between photoreceptor cells and optical plane wave based on the Finite Integration Technique (FIT).

  17. Transcriptome analysis reveals the contribution of thermal and the specific effects in cellular response to millimeter wave exposure.

    Science.gov (United States)

    Habauzit, Denis; Le Quément, Catherine; Zhadobov, Maxim; Martin, Catherine; Aubry, Marc; Sauleau, Ronan; Le Dréan, Yves

    2014-01-01

    Radiofrequency radiations constitute a new form of environmental pollution. Among them, millimeter waves (MMW) will be widely used in the near future for high speed communication systems. This study aimed therefore to evaluate the biocompatibility of MMW at 60 GHz. For this purpose, we used a whole gene expression approach to assess the effect of acute 60 GHz exposure on primary cultures of human keratinocytes. Controls were performed to dissociate the electromagnetic from the thermal effect of MMW. Microarray data were validated by RT-PCR, in order to ensure the reproducibility of the results. MMW exposure at 20 mW/cm2, corresponding to the maximum incident power density authorized for public use (local exposure averaged over 1 cm2), led to an increase of temperature and to a strong modification of keratinocyte gene expression (665 genes differentially expressed). Nevertheless, when temperature is artificially maintained constant, no modification in gene expression was observed after MMW exposure. However, a heat shock control did not mimic exactly the MMW effect, suggesting a slight but specific electromagnetic effect under hyperthermia conditions (34 genes differentially expressed). By RT-PCR, we analyzed the time course of the transcriptomic response and 7 genes have been validated as differentially expressed: ADAMTS6, NOG, IL7R, FADD, JUNB, SNAI2 and HIST1H1A. Our data evidenced a specific electromagnetic effect of MMW, which is associated to the cellular response to hyperthermia. This study raises the question of co-exposures associating radiofrequencies and other environmental sources of cellular stress.

  18. Transcriptome analysis reveals the contribution of thermal and the specific effects in cellular response to millimeter wave exposure.

    Directory of Open Access Journals (Sweden)

    Denis Habauzit

    Full Text Available Radiofrequency radiations constitute a new form of environmental pollution. Among them, millimeter waves (MMW will be widely used in the near future for high speed communication systems. This study aimed therefore to evaluate the biocompatibility of MMW at 60 GHz. For this purpose, we used a whole gene expression approach to assess the effect of acute 60 GHz exposure on primary cultures of human keratinocytes. Controls were performed to dissociate the electromagnetic from the thermal effect of MMW. Microarray data were validated by RT-PCR, in order to ensure the reproducibility of the results. MMW exposure at 20 mW/cm2, corresponding to the maximum incident power density authorized for public use (local exposure averaged over 1 cm2, led to an increase of temperature and to a strong modification of keratinocyte gene expression (665 genes differentially expressed. Nevertheless, when temperature is artificially maintained constant, no modification in gene expression was observed after MMW exposure. However, a heat shock control did not mimic exactly the MMW effect, suggesting a slight but specific electromagnetic effect under hyperthermia conditions (34 genes differentially expressed. By RT-PCR, we analyzed the time course of the transcriptomic response and 7 genes have been validated as differentially expressed: ADAMTS6, NOG, IL7R, FADD, JUNB, SNAI2 and HIST1H1A. Our data evidenced a specific electromagnetic effect of MMW, which is associated to the cellular response to hyperthermia. This study raises the question of co-exposures associating radiofrequencies and other environmental sources of cellular stress.

  19. Exposure-Response Analyses of Ramucirumab from Two Randomized, Phase III Trials of Second-line Treatment for Advanced Gastric or Gastroesophageal Junction Cancer.

    Science.gov (United States)

    Tabernero, Josep; Ohtsu, Atsushi; Muro, Kei; Van Cutsem, Eric; Oh, Sang Cheul; Bodoky, György; Shimada, Yasuhiro; Hironaka, Shuichi; Ajani, Jaffer A; Tomasek, Jiri; Safran, Howard; Chandrawansa, Kumari; Hsu, Yanzhi; Heathman, Michael; Khan, Azhar; Ni, Lan; Melemed, Allen S; Gao, Ling; Ferry, David; Fuchs, Charles S

    2017-10-01

    Ramucirumab is an IgG1 monoclonal antibody specific for the vascular endothelial growth factor receptor-2. Ramucirumab, 8 mg/kg every 2 weeks, administered as monotherapy (REGARD) or in combination with paclitaxel (RAINBOW), was safe and effective in patients with previously treated advanced gastric or gastroesophageal junction (GEJ) cancer. We evaluated exposure-efficacy and exposure-safety relationships of ramucirumab from two randomized, placebo-controlled phase III trials. Sparse pharmacokinetic samples were collected, and a population pharmacokinetic analysis was conducted to predict ramucirumab minimum trough concentration at steady state (Cmin,ss). Kaplan-Meier methods and Cox proportional hazards models were used to evaluate the ramucirumab exposure (Cmin,ss)-efficacy relationship to overall survival (OS) and progression-free survival (PFS). Logistic regression analyses were used to evaluate exposure-safety relationships. Analyses included 321 ramucirumab + paclitaxel and 335 placebo + paclitaxel patients from RAINBOW and 72 ramucirumab and 35 placebo patients from REGARD. Exposure-efficacy analysis showed ramucirumab Cmin,ss was a significant predictor of OS and PFS in both trials. Higher ramucirumab exposure was associated with longer OS and PFS. In RAINBOW, grade ≥3 hypertension, leukopenia, and neutropenia, but not febrile neutropenia, significantly correlated with Cmin,ss, with increased exposure leading to increased incidence. Exploratory exposure-response analyses suggest a positive relationship between efficacy and ramucirumab exposure with manageable toxicities at exposures generated from a dose of 8 mg/kg ramucirumab given every 2 weeks for patients with advanced gastric/GEJ cancer. These findings suggest an opportunity to further optimize benefit versus risk profiles of ramucirumab treatment in patients with gastric/GEJ cancer. Mol Cancer Ther; 16(10); 2215-22. ©2017 AACR. ©2017 American Association for Cancer Research.

  20. Age and sex as moderators of the placebo response – an evaluation of systematic reviews and meta-analyses across medicine.

    Science.gov (United States)

    Weimer, Katja; Colloca, Luana; Enck, Paul

    2015-01-01

    Predictors of the placebo response (PR) in randomized controlled trials (RCT) have been searched for ever since RCT have become the standard for testing novel therapies and age and gender are routinely documented data in all trials irrespective of the drug tested, its indication, and the primary and secondary end points chosen. To evaluate whether age and gender have been found to be reliable predictors of the PR across medical subspecialties, we extracted 75 systematic reviews, meta-analyses, and meta-regressions performed in major medical areas (neurology, psychiatry, internal medicine) known for high PR rates. The literature database used contains approximately 2,500 papers on various aspects of the genuine PR. These ‘meta-analyses’ were screened for statistical predictors of the PR across multiple RCT, including age and gender, but also other patient-based and design-based predictors of higher PR rates. Retrieved papers were sorted for areas and disease categories. Only 15 of the 75 analyses noted an effect of younger age to be associated with higher PR, and this was predominantly in psychiatric conditions but not in depression, and internal medicine but not in gastroenterology. Female gender was associated with higher PR in only 3 analyses. Among the patient-based predictors, the most frequently noted factor was lower symptom severity at baseline, and among the design- based factors, it was a randomization ratio that selected more patients to drugs than to placebo, more frequent study visits, and more recent trials that were associated with higher PR rates. While younger age may contribute to the PR in some conditions, sex does not. There is currently no evidence that the PR is different in the elderly. PR are, however, markedly influenced by the symptom severity at baseline, and by the likelihood of receiving active treatment in placebo- controlled trials. © 2014 S. Karger AG, Basel.

  1. Multivariate and phylogenetic analyses assessing the response of bacterial mat communities from an ancient oligotrophic aquatic ecosystem to different scenarios of long-term environmental disturbance.

    Science.gov (United States)

    Pajares, Silvia; Souza, Valeria; Eguiarte, Luis E

    2015-01-01

    Understanding the response of bacterial communities to environmental change is extremely important in predicting the effect of biogeochemical modifications in ecosystem functioning. The Cuatro Cienegas Basin is an ancient oasis in the Mexican Chihuahuan desert that hosts a wide diversity of microbial mats and stromatolites that have survived in extremely oligotrophic pools with nearly constant conditions. However, thus far, the response of these unique microbial communities to long-term environmental disturbances remains unexplored. We therefore studied the compositional stability of these bacterial mat communities by using a replicated (3x) mesocosm experiment: a) Control; b) Fluct: fluctuating temperature; c) 40C: increase to 40 ºC; d) UVplus: artificial increase in UV radiation; and f) UVmin: UV radiation protection. In order to observe the changes in biodiversity, we obtained 16S rRNA gene clone libraries from microbial mats at the end of the experiment (eight months) and analyzed them using multivariate and phylogenetic tools. Sequences were assigned to 13 major lineages, among which Cyanobacteria (38.8%) and Alphaproteobacteria (25.5%) were the most abundant. The less extreme treatments (Control and UVmin) had a more similar composition and distribution of the phylogenetic groups with the natural pools than the most extreme treatments (Fluct, 40C, and UVplus), which showed drastic changes in the community composition and structure, indicating a different community response to each environmental disturbance. An increase in bacterial diversity was found in the UVmin treatment, suggesting that protected environments promote the establishment of complex bacterial communities, while stressful environments reduce diversity and increase the dominance of a few Cyanobacterial OTUs (mainly Leptolyngbya sp) through environmental filtering. Mesocosm experiments using complex bacterial communities, along with multivariate and phylogenetic analyses of molecular data, can

  2. Multivariate and phylogenetic analyses assessing the response of bacterial mat communities from an ancient oligotrophic aquatic ecosystem to different scenarios of long-term environmental disturbance.

    Directory of Open Access Journals (Sweden)

    Silvia Pajares

    Full Text Available Understanding the response of bacterial communities to environmental change is extremely important in predicting the effect of biogeochemical modifications in ecosystem functioning. The Cuatro Cienegas Basin is an ancient oasis in the Mexican Chihuahuan desert that hosts a wide diversity of microbial mats and stromatolites that have survived in extremely oligotrophic pools with nearly constant conditions. However, thus far, the response of these unique microbial communities to long-term environmental disturbances remains unexplored. We therefore studied the compositional stability of these bacterial mat communities by using a replicated (3x mesocosm experiment: a Control; b Fluct: fluctuating temperature; c 40C: increase to 40 ºC; d UVplus: artificial increase in UV radiation; and f UVmin: UV radiation protection. In order to observe the changes in biodiversity, we obtained 16S rRNA gene clone libraries from microbial mats at the end of the experiment (eight months and analyzed them using multivariate and phylogenetic tools. Sequences were assigned to 13 major lineages, among which Cyanobacteria (38.8% and Alphaproteobacteria (25.5% were the most abundant. The less extreme treatments (Control and UVmin had a more similar composition and distribution of the phylogenetic groups with the natural pools than the most extreme treatments (Fluct, 40C, and UVplus, which showed drastic changes in the community composition and structure, indicating a different community response to each environmental disturbance. An increase in bacterial diversity was found in the UVmin treatment, suggesting that protected environments promote the establishment of complex bacterial communities, while stressful environments reduce diversity and increase the dominance of a few Cyanobacterial OTUs (mainly Leptolyngbya sp through environmental filtering. Mesocosm experiments using complex bacterial communities, along with multivariate and phylogenetic analyses of molecular

  3. Dynamic responses of offshore wind turbines subjected to random waves%近海风力发电高塔波浪随机动力响应分析

    Institute of Scientific and Technical Information of China (English)

    徐亚洲; 李杰

    2011-01-01

    Based on stochastic Fourier model of ocean wave, which originates from quasi-laminar wind-wave generation mechanism, probability density evolution method (PDEM) is employed to investigate dynamic response of an offshore wind turbine tower subjected to random wave, and probability density evolution process of the responses, response track with equal probability density function value, mean and standard deviation are presented. Linear wave theory and Morison equation are used to estimate time history of wave forces. The results indicate that PDEM can present time-variant probability density function and response track with the equal probability density function value. The mean and standard deviation calculated by PDEM have a good agreement with ones in terms of Monte Carlo method.%基于拟层流风波生成机制建立的随机Fourier海浪模型,采用概率密度演化理论研究了近海风力发电高塔在随机波浪作用下的动力响应问题,给出了结构响应概率密度函数的时间演化过程、概率密度等值线图及其均值和标准差.其中随机波浪力由线性波浪理论和M0rison公式计算.结果表明,概率密度演化方法可以获得结构波浪动力响应的时变概率密度函数和等概率密度响应轨迹.据此计算的均值及标准差与Monte Carlo计算结果吻合较好.

  4. Storms or cold fronts? What is really responsible for the extreme waves regime in the Colombian Caribbean coast

    Science.gov (United States)

    Otero, L. J.; Ortiz-Royero, J. C.; Ruiz-Merchan, J. K.; Higgins, A. E.; Henriquez, S. A.

    2015-05-01

    On Friday, 7 March 2009, a 200 m-long section of the tourist pier in Puerto Colombia collapsed under the impact of the waves generated by a cold front in the area. The aim of this study is to determine the contribution and importance of cold fronts and storms on extreme waves in different areas of the Colombian Caribbean to determine the degree of the threat posed by the flood processes to which these coastal populations are exposed and the actions to which coastal engineering constructions should be subject. In the calculation of maritime constructions, the most important parameter is the wave's height; therefore, it is necessary to definitively know the design wave height to which a coastal engineering structure should be resistant. This wave height varies according to the return period considered. Using Gumbel's extreme value methodology, the significant height values for the study area were calculated. The methodology was evaluated using data from the re-analysis of the spectral NOAA Wavewatch III (WW3) model for 15 points along the 1600 km of the Colombia Caribbean coast (continental and insular) of the last 15 years. The results demonstrated that the extreme waves caused by tropical cyclones and cold fronts have different effects along the Colombian Caribbean coast. Storms and hurricanes are of greater importance in the Guajira Peninsula (Alta Guajira). In the central area formed by Baja Guajira, Santa Marta, Barranquilla, and Cartagena, the strong influence of cold fronts on extreme waves is evident. On the other hand, in the southern region of the Colombian Caribbean coast, from the Gulf of Morrosquillo to the Gulf of Urabá, even though extreme waves are lower than in the previous regions, extreme waves are dominated mainly by the passage of cold fronts. Extreme waves in the San Andrés and Providencia insular region present a different dynamic from that in the continental area due to its geographic location. The wave heights in the extreme regime are

  5. Storms or cold fronts? What is really responsible for the extreme waves regime in the Colombian Caribbean coast

    Directory of Open Access Journals (Sweden)

    L. J. Otero

    2015-05-01

    Full Text Available On Friday, 7 March 2009, a 200 m-long section of the tourist pier in Puerto Colombia collapsed under the impact of the waves generated by a cold front in the area. The aim of this study is to determine the contribution and importance of cold fronts and storms on extreme waves in different areas of the Colombian Caribbean to determine the degree of the threat posed by the flood processes to which these coastal populations are exposed and the actions to which coastal engineering constructions should be subject. In the calculation of maritime constructions, the most important parameter is the wave's height; therefore, it is necessary to definitively know the design wave height to which a coastal engineering structure should be resistant. This wave height varies according to the return period considered. Using Gumbel's extreme value methodology, the significant height values for the study area were calculated. The methodology was evaluated using data from the re-analysis of the spectral NOAA Wavewatch III (WW3 model for 15 points along the 1600 km of the Colombia Caribbean coast (continental and insular of the last 15 years. The results demonstrated that the extreme waves caused by tropical cyclones and cold fronts have different effects along the Colombian Caribbean coast. Storms and hurricanes are of greater importance in the Guajira Peninsula (Alta Guajira. In the central area formed by Baja Guajira, Santa Marta, Barranquilla, and Cartagena, the strong influence of cold fronts on extreme waves is evident. On the other hand, in the southern region of the Colombian Caribbean coast, from the Gulf of Morrosquillo to the Gulf of Urabá, even though extreme waves are lower than in the previous regions, extreme waves are dominated mainly by the passage of cold fronts. Extreme waves in the San Andrés and Providencia insular region present a different dynamic from that in the continental area due to its geographic location. The wave heights in the

  6. Dynamical Response to the QBO in the Northern Winter Stratosphere: Signatures in Wave Forcing and Eddy Fluxes of Potential Vorticity

    Science.gov (United States)

    White, I. P.; Lu, H.; Mitchell, N. J.

    2015-12-01

    The quasi-biennial oscillation (QBO), a quasi-periodic oscillation of the stratospheric equatorial zonal wind between easterlies and westerlies, is known to affect the stratospheric circulation and transfer anomalies downward into the troposphere via a modulation of the winter polar vortex. However, the exact mechanism(s) governing this remain unclear. In this study, wave-mean-flow interactions associated with this effect, the so-called Holton-Tan effect (HTE), are studied using the ERA-Interim reanalysis dataset. Significant evidence of the HTE in isentropic coordinates is found, with a weaker and warmer polar vortex present when the lower stratospheric QBO is in its easterly phase (QBOe). For the first time, we quantify the QBO modulation of wave propagation, wave-mean-flow interaction and wave decay/growth via a calculation of potential vorticity (PV)-based measures, the zonal-mean momentum budget and up/down-gradient eddy PV fluxes. Stratosphere-troposphere coupling is also investigated with particular focus on the effect of the tropospheric subtropical jet on QBO modulation of the wave activity. In the subtropical to midlatitude lower stratosphere, QBOe is associated with an enhanced upward flux of wave activity across the tropopause, and corresponding wave convergence and wave growth, which leads to a stronger zonal-mean Brewer-Dobson Circulation and consequently a warmer polar region. In the middle stratosphere, QBOe is associated with increased poleward wave propagation, leading to enhanced wave convergence and in-situ wave growth at high latitudes and contributing to the weaker polar vortex. In agreement with recent studies, our results suggest that the critical-line effect cannot fully account for the wave anomalies associated with the HTE. Instead, it is suggestive of a new, additional mechanism that hinges on the QBO-induced meridional circulation effect on the latitudinal positioning of the subtropical jet. Under QBOe, the QBO-induced meridional

  7. Impact of age on aortic wave reflection responses to metaboreflex activation and its relationship with leg lean mass in post-menopausal women.

    Science.gov (United States)

    Figueroa, Arturo; Jaime, Salvador J; Johnson, Sarah A; Alvarez-Alvarado, Stacey; Campbell, Jeremiah C; Feresin, Rafaela G; Elam, Marcus L; Arjmandi, Bahram H

    2015-10-01

    Wave reflection (augmentation pressure [AP] and index [AIx]) is greater in older women than men. Resting AP is a better wave reflection index than AIx in older adults. The negative relationship between wave reflection and lean mass (LM) has been inconsistent. We investigated the impact of age and LM on aortic hemodynamic responses to metaboreflex activation in post-menopausal women. Post-menopausal women, younger and older (n=20 per group) than 60 years, performed 2-min isometric handgrip at 30% of maximal force followed by 3-min post-exercise muscle ischemia (PEMI). We measured carotid-femoral pulse wave velocity (cfPWV) and femoral-ankle PWV (faPWV) at rest, and aortic systolic blood pressure (aSBP), pulse pressure (aPP), AP, AIx, and AIx-adjusted for heart rate (AIx@75) at rest and during PEMI using tonometry. Arm and leg LM were measured by DEXA. Resting cfPWV, aSBP, and aPP were higher, while AIx@75 and leg LM were lower in older than younger women. aSBP and aPP increased similarly during PEMI in both groups. Increases in AP (Ppost-menopausal women. Our findings suggest that the increased AP response to PEMI is related to leg arterial stiffness and muscle loss in older women.

  8. The dynamic response of a hot-wire anemometer: IV. Sine-wave voltage perturbation testing for near-wall hot-wire/film probes and the presence of low-high frequency response characteristics

    Science.gov (United States)

    Teo, C. J.; Khoo, B. C.; Teo, C. J.; Chew, Y. T.

    2001-01-01

    Experiments were performed using the electronic sine-wave voltage-perturbation test to systematically study the frequency responses of near-wall hot-wire probes subjected in turn to varying magnitudes of convective velocity and different effects of wall influence. In addition, quartz-substrate hot-film gauges with various thicknesses of quartz coating were also investigated. Results of the high cut-off frequency obtained using the sine-wave test (fsine) were found to be in fair agreement with those obtained using the square-wave test (fS) both for hot-wire and for hot-film sensors. The sine-wave test response curve exhibited a distinct bulging effect for the hot-film gauges. For the hot-wire sensors, a much weaker bulging effect was also observed. In contrast to fS and fsine, the low frequency response characteristic corresponding to the location of the bulging effect (fbulge) compared much more favourably with the dynamic frequency response (fD) obtained by Khoo et al and Chew et al using a known near-wall fluctuating flow field. Freymuth's theory for non-cylindrical hot-film sensors incorporating the Bellhouse-Schultz model was applied to predict the responses of the hot-film wall gauges when they were subjected to electronic sine-wave testing and dynamic perturbation testing under different parametric conditions. Although it is one-dimensional in nature, the model is capable of predicting most of the trends observed in the present study and previous works by Khoo et al (1998a) and Chew et al (1998a).

  9. Chemical and laboratory analyses oceanographic data collected aboard the Wes Bordelon in the Gulf of Mexico from 2010-08-18 to 2010-08-22 in response to the Deepwater Horizon Oil Spill event (NODC Accession 0074863)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Chemical and laboratory analyses oceanographic data were collected aboard the Wes Bordelon in the Gulf of Mexico from 2010-08-18 to 2010-08-22 in response to the...

  10. Numerical Modeling of a Wave Energy Point Absorber

    DEFF Research Database (Denmark)

    Hernandez, Lorenzo Banos; Frigaard, Peter; Kirkegaard, Poul Henning

    2009-01-01

    The present study deals with numerical modelling of the Wave Star Energy WSE device. Hereby, linear potential theory is applied via a BEM code on the wave hydrodynamics exciting the floaters. Time and frequency domain solutions of the floater response are determined for regular and irregular seas....... Furthermore, these results are used to estimate the power and the energy absorbed by a single oscillating floater. Finally, a latching control strategy is analysed in open-loop configuration for energy maximization....

  11. Streaming patterns in Faraday waves

    CERN Document Server

    Périnet, Nicolas; Urra, Héctor; Mujica, Nicolás; Gordillo, Leonardo

    2016-01-01

    Waves patterns in the Faraday instability have been studied for decades. Besides the rich dynamics that can be observed on the waves at the interface, Faraday waves hide beneath them an elusive range of flow patterns --or streaming patterns-- which have not been studied in detail until now. The streaming patterns are responsible for a net circulation in the flow which are reminiscent of convection cells. In this article, we analyse these streaming flows by conducting experiments in a Faraday-wave setup. To visualize the flows, tracers are used to generate both trajectory maps and to probe the streaming velocity field via Particle Image Velocimetry (PIV). We identify three types of patterns and experimentally show that identical Faraday waves can mask streaming patterns that are qualitatively very different. Next we propose a three-dimensional model that explains streaming flows in quasi-inviscid fluids. We show that the streaming inside the fluid arises from a complex coupling between the bulk and the boundar...

  12. A Method to Retrieve the Multi-Receiver Moho Reflection Response from SH-Wave Scattering Coda in the Radiative Transfer Regime

    Science.gov (United States)

    Hartstra, I.; Wapenaar, C. P. A.

    2015-12-01

    We discuss a method to retrieve the multi-receiver Moho reflection response by interferometry from SH-wave coda in the 0.5-3 Hz frequency range. An image derived from a reflection response with a well defined virtual source would provide deterministic impedance contrasts, which can complement transmission tomography. For an accurate retrieval, cross-correlation interferometry requires the coda wave field to sample the imaging target and isotropically illuminate the receiver array. When these illumination requirements are not or only partially met, the stationary phase cannot be fully captured and artifacts will contaminate the retrieved reflection response. Here we conduct numerical scalar 2D finite difference simulations to investigate the challenging situation in which only shallow crustal earthquake sources illuminate the Moho and the response is recorded by a 2D linear array. We quantify to what extent the prevalence of scatterers in the crust can improve the illumination conditions and thus the retrieval of the Moho reflection. The accuracy of the retrieved reflection is evaluated for two physically different scattering regimes: the Rayleigh and Mie regime. We only use the earlier part of the scattering coda, because we have found that the later diffusive part does not significantly improve the retrieval. The density of the spherical scatterers is varied in order to change the scattering mean free path. This characteristic length scale is calculated for each model with the 2D radiative transfer equation, which is the governing equation in the earlier part of the scattering coda. The experiment is repeated for models of different geological settings derived from existing S-wave tomographies, which vary in Moho depth and reflectivity. The scattering mean free path can be approximated for real data if intrinsic attenuation is known, because the wavenumber-dependent scattering attenuation of the coherent wave amplitude is dependent on the scattering mean free path

  13. The mechanical response of piles with consideration of pile-soil interactions under a periodic wave pressure

    Institute of Scientific and Technical Information of China (English)

    朱峰; 徐卫亚; 王环玲

    2014-01-01

    The pile-soil interaction under wave loads is an extremely complex and difficult issue in engineering. In this study, a physical model test is designed based on the principle of the gravity similarity to obtain time histories of wave forces of unsteady regular waves, and to measure the magnitude and the distribution of wave forces acting on the piles. A numerical model and relevant numerical methods for the pile-soil contact surface are adopted based on the principles of elastic dynamics. For a practical project, the time histories of wave forces on the piles are obtained through physical model tests. The deformations of the piles in the pile-soil interactions and the distribution of the bending moment on the piles are studied. It is shown that, with the increase of the period of wave pressures, the absolute value of the horizontal displacement of the piles increases, the embedment depth of the piles increases, and the scope of influence of soils increases. The change of the bending moment on the piles is consistent with that of its theoretical results, and the proposed numerical method can very well simulate the properties of the piles.

  14. Storms or cold fronts: what is really responsible for the extreme waves regime in the Colombian Caribbean coastal region?

    Science.gov (United States)

    Otero, L. J.; Ortiz-Royero, J. C.; Ruiz-Merchan, J. K.; Higgins, A. E.; Henriquez, S. A.

    2016-02-01

    The aim of this study is to determine the contribution and importance of cold fronts and storms to extreme waves in different areas of the Colombian Caribbean in an attempt to determine the extent of the threat posed by the flood processes to which these coastal populations are exposed. Furthermore, the study wishes to establish the actions to which coastal engineering constructions should be subject. In the calculation of maritime constructions, the most important parameter is the height of the wave. For this reason, it is necessary to establish the design wave height to which a coastal engineering structure should be resistant. This wave height varies according to the return period considered. The significant height values for the areas focused on in the study were calculated in accordance with Gumbel's extreme value methodology. The methodology was evaluated using data from the reanalysis of the spectral National Oceanic and Atmospheric Administration (NOAA) WAVEWATCH III® (WW3) model for 15 points along the 1600 km of the Colombian Caribbean coastline (continental and insular) between the years 1979 and 2009. The results demonstrated that the extreme waves caused by tropical cyclones and those caused by cold fronts have different effects along the Colombian Caribbean coast. Storms and hurricanes are of greater importance in the Guajira Peninsula (Alta Guajira). In the central area (consisting of Baja Guajira, and the cities of Santa Marta, Barranquilla, and Cartagena), the strong impact of cold fronts on extreme waves is evident. However, in the southern region of the Colombian Caribbean coast (ranging from the Gulf of Morrosquillo to the Gulf of Urabá), the extreme values of wave heights are lower than in the previously mentioned regions, despite being dominated mainly by the passage of cold fronts. Extreme waves in the San Andrés and Providencia insular region present a different dynamic from that in the continental area due to their geographic location

  15. Investigation on the Cyclic Response of Superelastic Shape Memory Alloy (SMA Slit Damper Devices Simulated by Quasi-Static Finite Element (FE Analyses

    Directory of Open Access Journals (Sweden)

    Jong Wan Hu

    2014-02-01

    Full Text Available In this paper, the superelastic shape memory alloy (SMA slit damper system as an alternative design approach for steel structures is intended to be evaluated with respect to inelastic behavior simulated by refined finite element (FE analyses. Although the steel slit dampers conventionally used for aseismic design are able to dissipate a considerable amount of energy generated by the plastic yielding of the base materials, large permanent deformation may occur in the entire structure. After strong seismic events, extra damage repair costs are required to restore the original configuration and to replace defective devices with new ones. Innovative slit dampers fabricated by superelastic SMAs that automatically recover their initial conditions only by the removal of stresses without heat treatment are introduced with a view toward mitigating the problem of permanent deformation. The cyclically tested FE models are calibrated to experimental results for the purpose of predicting accurate behavior. This study also focuses on the material constitutive model that is able to reproduce the inherent behavior of superelastic SMA materials by taking phase transformation between austenite and martensite into consideration. The responses of SMA slit dampers are compared to those of steel slit dampers. Axial stress and strain components are also investigated on the FE models under cyclic loading in an effort to validate the adequacy of FE modeling and then to compare between two slit damper systems. It can be shown that SMA slit dampers exhibit many structural advantages in terms of ultimate strength, moderate energy dissipation and recentering capability.

  16. The 26 December 2001 Solar Eruptive Event Responsible for GLE63: III. CME, Shock Waves, and Energetic Particles

    Science.gov (United States)

    Grechnev, V. V.; Kiselev, V. I.; Uralov, A. M.; Klein, K.-L.; Kochanov, A. A.

    2017-08-01

    The SOL2001-12-26 moderate solar eruptive event (GOES importance M7.1, microwaves up to 4000 sfu at 9.4 GHz, coronal mass ejection (CME) speed 1446 km s-1) produced strong fluxes of solar energetic particles and ground-level enhancement (GLE) of cosmic-ray intensity (GLE63). To find a possible reason for the atypically high proton outcome of this event, we study multi-wavelength images and dynamic radio spectra and quantitatively reconcile the findings with each other. An additional eruption probably occurred in the same active region about half an hour before the main eruption. The latter produced two blast-wave-like shocks during the impulsive phase. The two shock waves eventually merged around the radial direction into a single shock traced up to 25 R_{⊙} as a halo ahead of the expanding CME body, in agreement with an interplanetary Type II event recorded by the Radio and Plasma Wave Investigation (WAVES) experiment on the Wind spacecraft. The shape and kinematics of the halo indicate an intermediate regime of the shock between the blast wave and bow shock at these distances. The results show that i) the shock wave appeared during the flare rise and could accelerate particles earlier than usually assumed; ii) the particle event could be amplified by the preceding eruption, which stretched closed structures above the developing CME, facilitated its lift-off and escape of flare-accelerated particles, enabled a higher CME speed and stronger shock ahead; iii) escape of flare-accelerated particles could be additionally facilitated by reconnection of the flux rope, where they were trapped, with a large coronal hole; and iv) the first eruption supplied a rich seed population accelerated by a trailing shock wave.

  17. Questions about elastic waves

    CERN Document Server

    Engelbrecht, Jüri

    2015-01-01

    This book addresses the modelling of mechanical waves by asking the right questions about them and trying to find suitable answers. The questions follow the analytical sequence from elementary understandings to complicated cases, following a step-by-step path towards increased knowledge. The focus is on waves in elastic solids, although some examples also concern non-conservative cases for the sake of completeness. Special attention is paid to the understanding of the influence of microstructure, nonlinearity and internal variables in continua. With the help of many mathematical models for describing waves, physical phenomena concerning wave dispersion, nonlinear effects, emergence of solitary waves, scales and hierarchies of waves as well as the governing physical parameters are analysed. Also, the energy balance in waves and non-conservative models with energy influx are discussed. Finally, all answers are interwoven into the canvas of complexity.

  18. On the response of a water surface to a surface pressure source moving at trans-critical gravity-capillary wave speeds

    Science.gov (United States)

    Masnadi, Naeem; Cho, Yeunwoo; Duncan, James H.; Akylas, Triantaphyllos

    2015-11-01

    The non-linear response of a water free surface to a pressure source moving at speeds near the minimum speed of linear gravity-capillary waves (Cmin ~ 23 cm/s) is investigated with experiments and theory. In the experiments, waves are generated by a vertically oriented air-jet that moves at a constant speed over the water surface in a long tank. The 3-D surface shape behind the air-jet is measured using a cinematic refraction-based technique combined with an LIF technique. At towing speeds just below Cmin, an unsteady pattern is formed where localized depressions periodically appear in pairs and move away from the source along the arms of a downstream V-shaped pattern. This behavior is analogous to the periodic shedding of solitary waves upstream of a source moving at the maximum wave speed in shallow water. The gravity-capillary depressions are rapidly damped by viscosity and their speed-amplitude characteristics closely match those from inviscid calculations of gravity-capillary lumps. The shedding frequency of the lumps in the present experiments increases with both increasing towing speed and air-flow rate. Predictions of this behavior using a model equation that incorporates damping and a quadratic nonlinearity are in good agreement with the experiments. The partial support of the National Science Foundation under grant OCE0751853 is gratefully acknowledged.

  19. Response characteristics of a long life type floating offshore airport in waves. 3rd Report. Response due to short waves and an attempt of active inclination control; Chojumyogata futaishiki kaijo kuko no harochu oto tokusei. Tanhachoiki no oto oyobi shisei seigyo no kokoromi

    Energy Technology Data Exchange (ETDEWEB)

    Hirayama, T.; Ma, N.; Nishio, O.; Sato, N. [Yokohama National University, Yokohama (Japan). Faculty of Engineering

    1996-12-31

    Notice was given on response characteristics in a short wavelength range of a large floating structure for an offshore airport consisting of semi-submersible replaceable type units, and influence of unit lacking. An attempt was also made on performing restoration of inclination change during unit lacking and suppression of long-cycle variation in waves by using air pressure control. The result of a numerical calculation based on a three-dimensional singular point method may be summarized as follows: mass force added vertically on columns in short wavelength range differs in the outer edges and the central part; relatively uniform values are shown in the central part; and interactive interference is recognized in wave forces in the vertical direction, but the influence therefrom decreases as the wave length decreases. Calculations on vertical movements and bending moments in waves were performed by using a mode synthesizing method. The calculations used fluid force which was calculated based on the three-dimensional singular point method utilizing symmetry with respect to each condition for a complete model plus unit lacking and unit lacking plus inclination control. As a result of verifying the calculations by using an experiment, relatively good agreement was achieved in either case. A high-frequency vibration experiment made clear the characteristics of elastic response in the short-wave length range. 14 refs., 14 figs.

  20. Tympanal travelling waves in migratory locusts.

    Science.gov (United States)

    Windmill, James F C; Göpfert, Martin C; Robert, Daniel

    2005-01-01

    Hearing animals, including many vertebrates and insects, have the capacity to analyse the frequency composition of sound. In mammals, frequency analysis relies on the mechanical response of the basilar membrane in the cochlear duct. These vibrations take the form of a slow vibrational wave propagating along the basilar membrane from base to apex. Known as von Békésy's travelling wave, this wave displays amplitude maxima at frequency-specific locations along the basilar membrane, providing a spatial map of the frequency of sound--a tonotopy. In their structure, insect auditory systems may not be as sophisticated at those of mammals, yet some are known to perform sound frequency analysis. In the desert locust, this analysis arises from the mechanical properties of the tympanal membrane. In effect, the spatial decomposition of incident sound into discrete frequency components involves a tympanal travelling wave that funnels mechanical energy to specific tympanal locations, where distinct groups of mechanoreceptor neurones project. Notably, observed tympanal deflections differ from those predicted by drum theory. Although phenomenologically equivalent, von Békésy's and the locust's waves differ in their physical implementation. von Békésy's wave is born from interactions between the anisotropic basilar membrane and the surrounding incompressible fluids, whereas the locust's wave rides on an anisotropic membrane suspended in air. The locust's ear thus combines in one structure the functions of sound reception and frequency decomposition.

  1. Extreme Value Predictions for Wave- and Wind-induced Loads on Floating Offshore Wind Turbines using FORM

    DEFF Research Database (Denmark)

    Joensen, Sunvard; Jensen, Jørgen Juncher; Mansour, Alaa E.

    2007-01-01

    probable wave episodes leading to given re-sponses. As an example the motions of floating foundations for offshore wind turbines are analysed taking into consid-eration both the wave and wind induced loads and con-sidering different mooring systems. The possible large horizontal motions make it important...

  2. Full-Wave Algorithm to Model Effects of Bedding Slopes on the Response of Subsurface Electromagnetic Geophysical Sensors near Unconformities

    CERN Document Server

    Sainath, Kamalesh

    2015-01-01

    We propose a full-wave pseudo-analytical numerical electromagnetic (EM) algorithm to model subsurface induction sensors, traversing planar-layered geological formations of arbitrary EM material anisotropy and loss, which are used, for example, in the exploration of hydrocarbon reserves. Unlike past pseudo-analytical planar-layered modeling algorithms that impose parallelism between the formation's bed junctions however, our method involves judicious employment of Transformation Optics techniques to address challenges related to modeling arbitrarily-oriented, relative slope (i.e., tilting) between said junctions. The algorithm exhibits this flexibility, both with respect to anisotropy in the formation layers as well as junction tilting, via employing special planar slabs that coat each "flattened" (i.e., originally tilted) planar interface, locally redirecting the incident wave within the coating slabs to cause wave fronts to interact with the flattened interfaces as if they were still tilted with a specific, ...

  3. The Wave Dragon

    DEFF Research Database (Denmark)

    Sørensen, H. C.; Hansen, R.; Friis-Madsen, E.

    2000-01-01

    The Wave Dragon is an offshore wave energy converter of the overtopping type, utilizing a patented wave reflector design to focus the waves towards a ramp, and the overtopping is used for electricity production through a set of Kaplan/propeller hydro turbines. During the last 2 years, excessive...... design an testing has been performed on a scale 1:50 model of the Wave Dragon, and on a scale 1:3:5 model turbine. Thus survivability, overtopping, hydraulic response, turbine performance and feasibility have been verified....

  4. Analysis of Standing Waves on GPR Hyperbolic Travel-Time Responses - Case Studies in a Fractured Granitic Rock and a Deteriorating Coastal Structure

    Directory of Open Access Journals (Sweden)

    Yun-Li Chen

    2007-01-01

    Full Text Available Utilizing Ground Penetrating Radar (GPR, emitted electromagnetic (EM standing waves can be generated in underground voids. This phenomenon can be employed for the detection of subterranean voids and fractures when one has a proper understanding of relation between the widest inner length in an underground vacant space and half an EM wavelength. In this study, indoor and outdoor small-scale experiments verified the generation of EM standing waves. These responses were then applied in an arched-top cave covered by a single layer of backfill at Gongzihliao, Taiwan. Further studies were carried out at two other sites, including a fracture located in a granite mountain without regolith on the surface at Kinmen, and a deteriorating fishing port in Nanfangao, northeast Taiwan. Applying a band-pass filter with bandwidth narrower than a typical two-octave bandwidth produced the required standing waves with recognizable positions of minimum amplitude. A hyperbolic travel-time (HTT curve revealing the minimum amplitude, known as standing-wave nodes, indicates the presence of an underground hollow diffractor with the widest inner length in the vacant space being larger than half an EM wavelength. However, a HTT curve without nodal points signifies a hollow object with the widest inner length smaller than half an EM wavelength or an underground solid diffractor. An underground arched-top cave was detected by nodal points in the arc-like curves. When emitting the radar waves toward a wall, the interval of the nodes was used for estimating the wavelength of receiving GPR signals. Identifying the occurrence of nodal points in HTT or HTTlike curves in radargrams may assist the GPR interpreting work for underground tunnels, drainages, cavities, fractures, or solid objects.

  5. Wave Overtopping Characteristics of the Wave Dragon

    DEFF Research Database (Denmark)

    Tedd, James; Kofoed, Jens Peter

    Simulation work has been used extensively with the Wave dragon and other overtopping devices to analyse the power production performance of them and to optimise the structural design and the control strategy. A time domain approach to this is well documented in Jakobsen & Frigaard 1999. Using...... measurements taken from the Wave Dragon Nissum Bredning prototype, some of the previous assumptions have been slightly modified and improved upon, so that the simulation method better represents the reality of what is occurring....

  6. Wave Overtopping Characteristics of the Wave Dragon

    DEFF Research Database (Denmark)

    Tedd, James; Kofoed, Jens Peter

    Simulation work has been used extensively with the Wave dragon and other overtopping devices to analyse the power production performance of them and to optimise the structural design and the control strategy. A time domain approach to this is well documented in Jakobsen & Frigaard 1999. Using...... measurements taken from the Wave Dragon Nissum Bredning prototype, some of the previous assumptions have been slightly modified and improved upon, so that the simulation method better represents the reality of what is occurring....

  7. Rain waves-wind waves interaction application to scatterometry

    Science.gov (United States)

    Kharif, C.; Giovanangeli, J. P.; Bliven, L.

    1989-01-01

    Modulation of a rain wave pattern by longer waves has been studied. An analytical model taking into account capillarity effects and obliquity of short waves has been developed. Modulation rates in wave number and amplitude have been computed. Experiments were carried out in a wave tank. First results agree with theoretical models, but higher values of modulation rates are measured. These results could be taken into account for understanding the radar response from the sea surface during rain.

  8. Human Heart Pulse Wave Responses Measured Simultaneously at Several Sensor Placements by Two MR-Compatible Fibre Optic Methods

    Directory of Open Access Journals (Sweden)

    Teemu Myllylä

    2012-01-01

    Full Text Available This paper presents experimental measurements conducted using two noninvasive fibre optic methods for detecting heart pulse waves in the human body. Both methods can be used in conjunction with magnetic resonance imaging (MRI. For comparison, the paper also performs an MRI-compatible electrocardiogram (ECG measurement. By the simultaneous use of different measurement methods, the propagation of pressure waves generated by each heart pulse can be sensed extensively in different areas of the human body and at different depths, for example, on the chest and forehead and at the fingertip. An accurate determination of a pulse wave allows calculating the pulse transit time (PTT of a particular heart pulse in different parts of the human body. This result can then be used to estimate the pulse wave velocity of blood flow in different places. Both measurement methods are realized using magnetic resonance-compatible fibres, which makes the methods applicable to the MRI environment. One of the developed sensors is an extraordinary accelerometer sensor, while the other one is a more common sensor based on photoplethysmography. All measurements, involving several test patients, were performed both inside and outside an MRI room. Measurements inside the MRI room were conducted using a 3-Tesla strength closed MRI scanner in the Department of Diagnostic Radiology at the Oulu University Hospital.

  9. Structural response analysis of very large floating structures in waves using one-dimensional finite element model; Ichijigen yugen yoso model ni yoru choogata futai no harochu kozo oto kaiseki

    Energy Technology Data Exchange (ETDEWEB)

    Fujikubo, M.; Yao, T.; Oida, H. [Hiroshima University, Hiroshima (Japan). Faculty of Engineering

    1996-12-31

    Formulation was made on a one-dimensional beam finite element which is effective in analyzing structural response of very large floating structures by modeling them on beams on an elastic foundation. This element allows strict solution of vibration response in the beams on the elastic foundation to be calculated efficiently for a case where mass and rigidity change in the longitudinal direction. This analysis method was used to analyze structural response of a large pontoon-type floating structure to investigate mass in the end part for the structural response and the effect of decay while passing the structure. With a pontoon-type floating structure, reduction in bends and bending stress in the end part of the floating structure is important in designing the structure. Reducing the mass in the end part is effective as a means to avoid resonance in these responses and reduce the responses. Increase in rigidity of a floating structure shifts the peak in quasi-static response to lower frequency side, and reduces response in resonance, hence it is advantageous for improving the response. Since incident waves decay while passing through the floating structure, response in the lower wave side decreases. The peak frequency in the quasi-static response also decreases at the end part of the structure in the upper wave side due to decay in wave force. 7 refs., 11 figs., 1 tab.

  10. An Analysis of the Loads on and Dynamic Response of a Floating Flexible Tube in Waves and Currents

    Science.gov (United States)

    2014-05-09

    the tube about 4.57 meters. The CFD code associated with the SolidWorks Flow Simulation tool was applied for this application. Flow Simulation uses...Liquid-Filled Membrane Structure in Waves," Journal of Fluids and Structures, no. 9, pp. 937-956, 1995. [16] SolidWorks , "Flow Simulation 2012...Technical Reference," SolidWorks , 2012. [17] NTNU, "TMR7 Experimental Methods in Marine Hydrodynamics – lecture in week 37," [Online]. Available: http

  11. Investigation of the H reflexes, F waves and sympathetic skin response with electromyography (EMG) in patients with stroke and the determination of the relationship with functional capacity.

    Science.gov (United States)

    Çakır, Tuncay; Evcik, Fatma Deniz; Subaşı, Volkan; Demirdal, Ümit Seçil; Kavuncu, Vural

    2015-09-01

    The purpose of the study was to evaluate the relationship between sympathetic skin responses (SSR), electrodiagnostic reflex activities (F wave, H reflex), and functional capacity in post-stroke patients. The study comprised 40 hemiplegia patients (mean age 57.8 ± 10.9 years) and 40 healthy volunteers (mean age 557 ± 85 years). In electrophysiological studies, SSR, F wave and H reflex were evaluated and for the functional capacities of patients, FIM scores and Brunnstrom stages were calculated. There was no statistical significant difference between SSR latency and amplitude in the hemiplegic and non-hemiplegic extremities of patients (p > 0.05). SSR latency values of patients were higher than those of controls (p < 0.05). Amplitude values of paretic arms were significantly lower than the control group extremities (p < 0.05). There was a significant correlation between SSR amplitude values and FIM scores. A significant increase in H max/M max amplitude rate was detected in the affected side (p < 0.05) and F-wave mean latency values of the affected side were found to be significantly lower in the control group (p < 0.05).

  12. A six-arm olfactometer for analysing olfactory responses of Goniozus legneri Gordh (Hymenoptera: Bethylidae, the larval ectoparasitoid of carob moth

    Directory of Open Access Journals (Sweden)

    M. Aleosfoor

    2014-12-01

    Full Text Available The behavioural responses of Goniozus legneri were investigated in a six-arm olfactometer. Among the different odours examined, carob moth (Ectomyelois ceratoniae Zeller frass elicited the highest olfactory responses, while Ephestisa larvae, which were less suitable hosts, elicited the lowest response. The different preferences to various odours suggest that Goniozus legneri can discriminate among suitable and less suitable insect hosts.

  13. Electron Acoustic Waves and the Search for a Truly Self-Consistent Large-Amplitude Plasma Response

    Science.gov (United States)

    Johnston, Tudor; Afeyan, Bedros

    2003-10-01

    We examine some theoretical nonlinear Vlasov work invoked in connection with recent laser-plasma experiments [1] on Electron Acoustic Waves and their stimulated scatter (SEAS). Earlier work discussed [2-5] is then related to more recent theory [6] used to interpret [1]. All this [2-6] is then related the recent Vlasov-Poisson findings of Afeyan et al. [7] on Kinetic Electrostatic Electron Nonlinear (KEEN) waves. (Part of this work was performed under the auspices of the U.S. Department of Energy under grant number DE-FG03-NA00059.) [1] D.S. Montgomery et al., Phys. Rev. Lett. 87, 155001 (2001), Phys. Plasmas 9, 2311(2002). [2] I.B. Bernstein et al., Phys.Rev. 108, 546 (1957). [3] W.P. Allis, paper no. 3 pp. 21-42, in In Honor of Philip M. Morse, ed. H. Feshbach and K. Ingard, MIT Press, Cambridge, MA, (1969). (Source for V.B. Krapchev and A.K. Ram, Phys. Rev. A, 22, 1229 (1980)). [4] H. Schamel, Phys. Scr. 20, 336 (1979), Phys. Rep. 140, 161 (1986), Phys. Plasmas 7, 4831 (2000). [5] J.P. Holloway and J.J. Dorning, Phys. Lett. A 138, 279 (1989) and Phys. Rev. A 44, 3856 (1991). [6] H. A. Rose and D. A. Russell, Phys. Plasmas 8, 4784 (2001). [7] B. B. Afeyan et al., "Optical Mixing Generated Kinetic Electrostatic Electron Nonlinear (KEEN) Waves", manuscript in preparation and poster at this conference.

  14. Electromagnetic wave energy converter

    Science.gov (United States)

    Bailey, R. L. (Inventor)

    1973-01-01

    Electromagnetic wave energy is converted into electric power with an array of mutually insulated electromagnetic wave absorber elements each responsive to an electric field component of the wave as it impinges thereon. Each element includes a portion tapered in the direction of wave propagation to provide a relatively wideband response spectrum. Each element includes an output for deriving a voltage replica of the electric field variations intercepted by it. Adjacent elements are positioned relative to each other so that an electric field subsists between adjacent elements in response to the impinging wave. The electric field results in a voltage difference between adjacent elements that is fed to a rectifier to derive dc output power.

  15. Short baseline variations in site response and wave-propagation effects and their structural causes: Four examples in and around the santa clara valley, California

    Science.gov (United States)

    Hartzell, S.; Ramirez-Guzman, L.; Carver, D.; Liu, P.

    2010-01-01

    Ground motion records of local and regional events from a portable array are used to investigate the structural causes of variations in ground motion over distances of a few hundred meters to a few kilometers in the sedimentary basin environment of the Santa Clara Valley, California, and its margins. Arrays of portable seismic stations are used to target four study areas with different ground motion patterns: (1) an edge of the alluvial basin extending up onto a marginal ridge (Blossom Hill), (2) a Cenozoic basin with a nearly flat bottom (Cupertino Basin), (3) a long, narrow Cenozoic basin with a steep V profile (Evergreen Basin), and (4) a line perpendicular to the trace of the Hayward fault. Average peak velocities on Blossom Hill from local earthquakes are a factor of 2.5 times higher than nearby valley sites. Three-dimensional (3D) modeling is used to conclude that the majority of the amplification is due to lower shear-wave velocities along a local fault zone (Shannon–Berrocal). Site amplification over the Cupertino Basin in the frequency band 0.5–4 Hz is generally low (less than 2.0 relative to a Mesozoic rock site) and spatially uniform. This response is attributed to the shallow, flat-bottomed shape of the basin and the uniform, flat-laying sedimentary fill. In contrast, site amplification in the Evergreen Basin generally exceeds 3.0 and is attributed to the deep, V-shaped geometry of the basin and younger sedimentary fill. 3D waveform modeling shows the elongated shape of the Evergreen Basin causes more efficient trapping of long-period waves for sources along the long axis of the basin. A low-velocity zone is postulated along the Hayward fault with a width between 100 and 200 m, based on elevated site response along the fault trace and 4.5-Hz fault zone guided waves on the horizontal components of stations near the fault.

  16. Electromagnetic Waves

    DEFF Research Database (Denmark)

    This book is dedicated to various aspects of electromagnetic wave theory and its applications in science and technology. The covered topics include the fundamental physics of electromagnetic waves, theory of electromagnetic wave propagation and scattering, methods of computational analysis...

  17. Response of the Adriatic Sea to an intense cold air outbreak: Dense water dynamics and wave-induced transport

    Science.gov (United States)

    Benetazzo, A.; Bergamasco, A.; Bonaldo, D.; Falcieri, F. M.; Sclavo, M.; Langone, L.; Carniel, S.

    2014-11-01

    The paper describes formation and spreading of dense shelf waters in the Adriatic Sea (North Adriatic Dense Water, NAdDW) during the winter of 2012 as a consequence of an intense and long cold air outbreak of northeasterly Bora winds. As a result, during February 2012 northern Adriatic Sea water temperature dropped to about 6 °C and density exceeded 1030 kg/m3, most likely the maximum value since 1929. NAdDW dynamics has been investigated by means of a 3-D ocean-wave coupled model running on a high resolution and eddy-permitting grid. The numerical experiments have relied on the Coupled-Ocean-Atmosphere-Wave-Sediment-Transport (COAWST) system forced one-way with atmospheric forcings provided by the model COSMO-I7. A suite of observational data has been used to characterize the Bora event and evaluate numerical model performance. At sub-basin scales, the newly formed waters flowing southerly have produced a water renewal of the northern Adriatic, as more than 50% of water volumes have left the basin. Dense waters volume transports, evaluated through different Adriatic cross-sections, have been modulated by tides (damped for the densest water masses) and reached about 1 Sv. The contribution of wave-induced forcings has been quantified and examined, indicating that these represent a major driving mechanism during NAdDW production and spreading phases. This work provides evidence that NAdDW is spread accordingly with two different mechanisms: at early stages of its formation, the wind-driven ocean circulation pushes newly formed waters to leave the northern basin with relatively high speeds (about 0.30 m/s). Later on, remaining NAdDW leaks slowly out (0.09 m/s as average) from the production site. Residence times of dense waters in the north, middle, and south Adriatic Sea are also documented.

  18. ARF6 promotes the formation of Rac1 and WAVE-dependent ventral F-actin rosettes in breast cancer cells in response to epidermal growth factor.

    Directory of Open Access Journals (Sweden)

    Valentina Marchesin

    Full Text Available Coordination between actin cytoskeleton assembly and localized polarization of intracellular trafficking routes is crucial for cancer cell migration. ARF6 has been implicated in the endocytic recycling of surface receptors and membrane components and in actin cytoskeleton remodeling. Here we show that overexpression of an ARF6 fast-cycling mutant in MDA-MB-231 breast cancer-derived cells to mimick ARF6 hyperactivation observed in invasive breast tumors induced a striking rearrangement of the actin cytoskeleton at the ventral cell surface. This phenotype consisted in the formation of dynamic actin-based podosome rosette-like structures expanding outward as wave positive for F-actin and actin cytoskeleton regulatory components including cortactin, Arp2/3 and SCAR/WAVE complexes and upstream Rac1 regulator. Ventral rosette-like structures were similarly induced in MDA-MB-231 cells in response to epidermal growth factor (EGF stimulation and to Rac1 hyperactivation. In addition, interference with ARF6 expression attenuated activation and plasma membrane targeting of Rac1 in response to EGF treatment. Our data suggest a role for ARF6 in linking EGF-receptor signaling to Rac1 recruitment and activation at the plasma membrane to promote breast cancer cell directed migration.

  19. A coatable, light-weight, fast-response nanocomposite sensor for the in situ acquisition of dynamic elastic disturbance: from structural vibration to ultrasonic waves

    Science.gov (United States)

    Zeng, Zhihui; Liu, Menglong; Xu, Hao; Liu, Weijian; Liao, Yaozhong; Jin, Hao; Zhou, Limin; Zhang, Zhong; Su, Zhongqing

    2016-06-01

    Inspired by an innovative sensing philosophy, a light-weight nanocomposite sensor made of a hybrid of carbon black (CB)/polyvinylidene fluoride (PVDF) has been developed. The nanoscalar architecture and percolation characteristics of the hybrid were optimized in order to fulfil the in situ acquisition of dynamic elastic disturbance from low-frequency vibration to high-frequency ultrasonic waves. Dynamic particulate motion induced by elastic disturbance modulates the infrastructure of the CB conductive network in the sensor, with the introduction of the tunneling effect, leading to dynamic alteration in the piezoresistivity measured by the sensor. Electrical analysis, morphological characterization, and static/dynamic electromechanical response interrogation were implemented to advance our insight into the sensing mechanism of the sensor, and meanwhile facilitate understanding of the optimal percolation threshold. At the optimal threshold (˜6.5 wt%), the sensor exhibits high fidelity, a fast response, and high sensitivity to ultrafast elastic disturbance (in an ultrasonic regime up to 400 kHz), yet with an ultralow magnitude (on the order of micrometers). The performance of the sensor was evaluated against a conventional strain gauge and piezoelectric transducer, showing excellent coincidence, yet a much greater gauge factor and frequency-independent piezoresistive behavior. Coatable on a structure and deployable in a large quantity to form a dense sensor network, this nanocomposite sensor has blazed a trail for implementing in situ sensing for vibration- or ultrasonic-wave-based structural health monitoring, by striking a compromise between ‘sensing cost’ and ‘sensing effectiveness’.

  20. The Impact of the Spectral Response of an Achromatic Half-Wave Plate on the Measurement of the Cosmic Microwave Background Polarization

    CERN Document Server

    Bao, C; Baccigalupi, C; Didier, J; Hanany, S; Jaffe, A; Johnson, B R; Leach, S; Matsumura, T; Miller, A; O'Dea, D

    2011-01-01

    We study the impact of the spectral dependence of the linear polarization rotation induced by an achromatic half-wave plate on measurements of cosmic microwave background polarization in the presence of astrophysical foregrounds. We focus on the systematic effects induced on the measurement of inflationary gravitational waves by uncertainties in the polarization and spectral index of Galactic dust. We find that for the experimental configuration and noise levels of the balloon-borne EBEX experiment, which has three frequency bands centered at 150, 250, and 410 GHz, a crude dust subtraction process mitigates systematic effects to below detectable levels for 10% polarized dust and tensor to scalar ratio of as low as r = 0.01. We also study the impact of uncertainties in the spectral response of the instrument. With a top-hat model of the spectral response for each band, characterized by band-center and band-width, and with the same crude dust subtraction process, we find that these parameters need to be determi...

  1. Exposure-response analyses for soluble platinum-salt exposed workers and sensitisation: a retrospective cohort study among newly exposed workers using routinely collected surveillance data

    NARCIS (Netherlands)

    Heederik, Dick; Jacobs, Jose; Samadi, Sadegh; Portengen, Lutzen; van Rooy, Frits; Houba, Remko

    OBJECTIVES: Soluble platinum salts are well known respiratory sensitising agents leading to work related sensitisation in the work environment. No quantitative exposure response relation has been described for soluble platinum salts. The objective of this study was to explore exposure response

  2. Thyroid hormone-regulated gene expression in juvenile mouse liver: identification of thyroid response elements using microarray profiling and in silico analyses

    Directory of Open Access Journals (Sweden)

    Paquette Martin A

    2011-12-01

    Full Text Available Abstract Background Disruption of thyroid hormone signalling can alter growth, development and energy metabolism. Thyroid hormones exert their effects through interactions with thyroid receptors that directly bind thyroid response elements and can alter transcriptional activity of target genes. The effects of short-term thyroid hormone perturbation on hepatic mRNA transcription in juvenile mice were evaluated, with the goal of identifying genes containing active thyroid response elements. Thyroid hormone disruption was induced from postnatal day 12 to 15 by adding goitrogens to dams' drinking water (hypothyroid. A subgroup of thyroid hormone-disrupted pups received intraperitoneal injections of replacement thyroid hormones four hours prior to sacrifice (replacement. An additional group received only thyroid hormones four hours prior to sacrifice (hyperthyroid. Hepatic mRNA was extracted and hybridized to Agilent mouse microarrays. Results Transcriptional profiling enabled the identification of 28 genes that appeared to be under direct thyroid hormone-regulation. The regulatory regions of the genome adjacent to these genes were examined for half-site sequences that resemble known thyroid response elements. A bioinformatics search identified 33 thyroid response elements in the promoter regions of 13 different genes thought to be directly regulated by thyroid hormones. Thyroid response elements found in the promoter regions of Tor1a, 2310003H01Rik, Hect3d and Slc25a45 were further validated by confirming that the thyroid receptor is associated with these sequences in vivo and that it can bind directly to these sequences in vitro. Three different arrangements of thyroid response elements were identified. Some of these thyroid response elements were located far up-stream (> 7 kb of the transcription start site of the regulated gene. Conclusions Transcriptional profiling of thyroid hormone disrupted animals coupled with a novel bioinformatics search

  3. On the wave induced responses for a high-speed hydrofoil catamaran. Part 2. Cabin connected to hull by spring and response to vibration; Suichuyokutsuki kosoku sodotei no harochu oto ni tsuite. 2. Dokuritsu kozogata cabin to yodo oto

    Energy Technology Data Exchange (ETDEWEB)

    Nobukawa, H.; Kitamura, M.; Kawamura, T. [Hiroshima University, Hiroshima (Japan). Faculty of Engineering

    1996-04-10

    A high-speed hydrofoil catamaran under development has such a structure that an independent cabin is mounted on catamaran hulls, the cabin is connected with the hulls by using four soft springs, and hydrofoils are attached to the front and rear of the cabin. The structural design conception was as follows: the self-weight of the cabin is supported by lifting power of the hydrofoils while the boat is cruising; longitudinal motions of the catamaran hulls are absorbed by soft spring struts to make the motions more difficult to be transmitted into the cabin; and vibration excited by engines rotating at high speeds, attached to rear of the catamaran hulls, is not transmitted directly to the cabin structurally. A towing experiment was carried out by using divided models of about 1/10 scale in counter waves and regular waves to investigate their vibration response characteristics in waves. Furthermore, an experimental boat made of aluminum alloy with about 1/3 scale of the design boat was attached with composite structural struts made of springs and rubber parts to perform cruising experiments on an actual sea area. As a result, it was found that vibration excited by main engines in the catamaran hulls is transmitted very little to the cabin. 2 refs., 10 figs., 1 tab.

  4. Non-ionizing radiofrequency electromagnetic waves traversing the head can be used to detect cerebrovascular autoregulation responses.

    Science.gov (United States)

    Oziel, M; Hjouj, M; Gonzalez, C A; Lavee, J; Rubinsky, B

    2016-02-22

    Monitoring changes in non-ionizing radiofrequency electromagnetic waves as they traverse the brain can detect the effects of stimuli employed in cerebrovascular autoregulation (CVA) tests on the brain, without contact and in real time. CVA is a physiological phenomenon of importance to health, used for diagnosis of a number of diseases of the brain with a vascular component. The technology described here is being developed for use in diagnosis of injuries and diseases of the brain in rural and economically underdeveloped parts of the world. A group of nine subjects participated in this pilot clinical evaluation of the technology. Substantial research remains to be done on correlating the measurements with physiology and anatomy.

  5. Estimation of liquid properties by inverse problem analysis based on shear horizontal surface acoustic wave sensor responses

    Science.gov (United States)

    Ueda, Kento; Kondoh, Jun

    2017-07-01

    A shear horizontal surface acoustic wave (SH-SAW) sensor can detect liquid properties, such as viscosity, density, permittivity, and conductivity. The advantage of using the SH-SAW sensors is the simultaneous detection of the mechanical and electrical properties of liquids. In this paper, we proposed a method of estimating the density and viscosity of liquids based on the inverse problem analysis. Glycerol or ethanol aqueous solutions were measured. The estimated and literature values were compared. For glycerol aqueous solutions, when the concentration is low, those values agree well. However, when the concentration is high, those values did not agree because the bulk modulus of glycerin solutions cannot be assumed as constant. On the other hand, as the bulk modulus of ethanol aqueous solutions can be assumed to be the same as that of water, the deviations between those values were small. Therefore, the proposed method is effective when the bulk modulus is assumed as constant.

  6. Circadian waves of expression of the APRR1/TOC1 family of pseudo-response regulators in Arabidopsis thaliana: insight into the plant circadian clock.

    Science.gov (United States)

    Matsushika, A; Makino, S; Kojima, M; Mizuno, T

    2000-09-01

    The Arabidopsis pseudo-response regulator, APRR1, has a unique structural design containing a pseudo-receiver domain and a C-terminal CONSTANS motif. This protein was originally characterized as a presumed component of the His-to-Asp phosphorelay systems in Arabidopsis thaliana. Recently, it was reported that APRR1 is identical to the TOC1 gene product, a mutational lesion of which affects the periods of many circadian rhythms in Arabidopsis plants. TOC1 is believed to be a component of the presumed circadian clock (or central oscillator). Based on these facts, in this study four more genes, each encoding a member of the APRR1/TOC1 family of pseudo-response regulators were identified and characterized with special reference to circadian rhythms. It was found that all these members of the APRR1/TOC1 family (APRR1, APRR3, APRR5, APRR7, and APRR9) are subjected to a circadian rhythm at the level of transcription. Furthermore, in a given 24 h period, the APRR-mRNAs started accumulating sequentially after dawn with 2-3 h intervals in the order of APRR9-->APRR7-->APRR5-->APRR3-->APRR1. These sequential events of transcription, termed 'circadian waves of APRR1/TOCI', were not significantly affected by the photoperiod conditions, if any (e.g. both long and short days), and the expression of APRR9 was first boosted always after dawn. Among these APRRs, in fact, only the expression of APRR9 was rapidly and transiently induced also by white light, whereas such light responses of others were very dull, if any. These results collectively support the view that these members of the APRR1/TOC1 family are together all involved in an as yet unknown mechanism underlying the Arabidopsis circadian clock. Here we propose that the circadian waves of the APRR1/TOC1 family members are most likely a molecular basis of such a biological clock in higher plants.

  7. Live Poultry Exposure and Public Response to Influenza A(H7N9) in Urban and Rural China during Two Epidemic Waves in 2013-2014

    Science.gov (United States)

    Fang, Vicky J.; Li, Fu; Zeng, Lingjia; Wu, Joseph T.; Li, Zhongjie; Leung, Gabriel M.; Yu, Hongjie

    2015-01-01

    Background The novel influenza A(H7N9) virus has caused 2013 spring and 2013–2014 winter waves of human infections since its first emergence in China in March 2013. Exposure to live poultry is a risk factor for H7N9 infection. Public psychobehavioral responses often change during progression of an epidemic. Methods We conducted population-based surveys in southern China to examine human exposure to live poultry, and population psychological response and behavioral changes in the two waves. In Guangzhou, an urban area of Guangdong province, we collected data using telephone surveys with random digit dialing in May-June 2013 and again in December 2013 to January 2014. In Zijin county, a rural area of the same province, we used door-to-door surveys under a stratified sampling design in July 2013 and again in December 2013 to January 2014. All responses were weighted by age and sex to the respective adult populations. Findings Around half of the urban respondents (53.8%) reported having visited LPMs in the previous year in the first survey, around double that reported in the second survey (27.7%). In the rural surveys, around half of the participants reported raising backyard poultry in the past year in the first survey, increasing to 83.2% participants in the second survey. One third of urban subjects supported the permanent closure of LPMs in the first and second surveys, and factors associated with support for closure included female sex, higher level of worry towards H7N9, and worry induced by a hypothetical influenza-like illness. Conclusions Our study indicated high human exposure to live poultry and low support for permanent closure of markets in both urban and rural residents regardless of increased worry during the epidemic. PMID:26367002

  8. Live Poultry Exposure and Public Response to Influenza A(H7N9 in Urban and Rural China during Two Epidemic Waves in 2013-2014.

    Directory of Open Access Journals (Sweden)

    Peng Wu

    Full Text Available The novel influenza A(H7N9 virus has caused 2013 spring and 2013-2014 winter waves of human infections since its first emergence in China in March 2013. Exposure to live poultry is a risk factor for H7N9 infection. Public psychobehavioral responses often change during progression of an epidemic.We conducted population-based surveys in southern China to examine human exposure to live poultry, and population psychological response and behavioral changes in the two waves. In Guangzhou, an urban area of Guangdong province, we collected data using telephone surveys with random digit dialing in May-June 2013 and again in December 2013 to January 2014. In Zijin county, a rural area of the same province, we used door-to-door surveys under a stratified sampling design in July 2013 and again in December 2013 to January 2014. All responses were weighted by age and sex to the respective adult populations.Around half of the urban respondents (53.8% reported having visited LPMs in the previous year in the first survey, around double that reported in the second survey (27.7%. In the rural surveys, around half of the participants reported raising backyard poultry in the past year in the first survey, increasing to 83.2% participants in the second survey. One third of urban subjects supported the permanent closure of LPMs in the first and second surveys, and factors associated with support for closure included female sex, higher level of worry towards H7N9, and worry induced by a hypothetical influenza-like illness.Our study indicated high human exposure to live poultry and low support for permanent closure of markets in both urban and rural residents regardless of increased worry during the epidemic.

  9. Pulsed Wave Doppler Ultrasound Is Useful to Assess Vasomotor Response in Patients with Multiple System Atrophy and Well Correlated with Tilt Table Study

    Directory of Open Access Journals (Sweden)

    Ke-Vin Chang

    2012-01-01

    Full Text Available The study aim was to assess sympathetic vasomotor response (SVR by using pulsed wave Doppler (PWD ultrasound in patients with multiple system atrophy (MSA and correlate with the tilt table study. We recruited 18 male patients and 10 healthy men as controls. The SVR of the radial artery was evaluated by PWD, using inspiratory cough as a provocative maneuver. The response to head-up tilt was studied by a tilt table with simultaneous heart rate and blood pressure recording. The hemodynamic variables were compared between groups, and were examined by correlation analysis. Regarding SVR, MSA patients exhibited a prolonged latency and less heart rate acceleration following inspiratory cough. Compared with the tilt table test, the elevation of heart rate upon SVR was positively correlated to the increase of heart rate after head-up tilt. The correlation analysis indicated that the magnitude of blood pressure drop from supine to upright was positively associated with the SVR latency but negatively correlated with the heart rate changes upon SVR. The present study demonstrated that blunted heart rate response might explain MSA's vulnerability to postural challenge. PWD may be used to predict cardiovascular response to orthostatic stress upon head-up tilt in MSA patients.

  10. Polar Plasma Wave Investigation Data Analysis in the Extended Mission

    Science.gov (United States)

    Gurnett, Donald A.

    2004-01-01

    The low latitude boundary layer (LLBL) is a region where solar wind momentum and energy is transferred to the magnetosphere. Enhanced "broadband" electric plasma waves from less than 5 Hz to 10(exp 5) Hz and magnetic waves from less than 5 Hz to the electron cyclotron frequency are characteristic of the LLBL. Analyses of Polar plasma waves show that these "broadband" waves are actually discrete electrostatic and electromagnetic modes as well as solitary bipolar pulses (electron holes). It is noted that all wave modes can be generated by approx. 100 eV to approx. 10 keV auroral electrons and protons. We will review wave-particle interactions, with focus on cross-diffusion rates and the contributions of such interactions toward the formation of the boundary layer. In summary, we will present a scenario where the global solar wind-magnetosphere interaction is responsible for the auroral zone particle beams, and hence for the generation of plasma waves and the formation of the boundary layer. It is speculated that all planetary magnetospheres will have boundary layers and they will be characterized by similar currents and plasma wave modes.

  11. Systematic review including re-analyses of 1148 individual data sets of central venous pressure as a predictor of fluid responsiveness

    DEFF Research Database (Denmark)

    Eskesen, T G; Wetterslev, M; Perner, A

    2016-01-01

    PURPOSE: Central venous pressure (CVP) has been shown to have poor predictive value for fluid responsiveness in critically ill patients. We aimed to re-evaluate this in a larger sample subgrouped by baseline CVP values. METHODS: In April 2015, we systematically searched and included all clinical...... studies evaluating the value of CVP in predicting fluid responsiveness. We contacted investigators for patient data sets. We subgrouped data as lower (12 mmHg) baseline CVP. RESULTS: We included 51 studies; in the majority, mean/median CVP values were...... in which the lower 95 % CI crossed 0.50. We identified some positive and negative predictive value for fluid responsiveness for specific low and high values of CVP, respectively, but none of the predictive values were above 66 % for any CVPs from 0 to 20 mmHg. There were less data on higher CVPs...

  12. Analysis of Nonlinear Soil-Structure Interaction Effects on the response of Three-Dimensional Frame Structures using a One-Direction Three-ComponentWave Propagation Model

    CERN Document Server

    d'Avila, Maria Paola Santisi

    2016-01-01

    In this paper, a model of one-directional propagation of three-component seismic waves in a nonlinear multilayered soil profile is coupled with a multi-story multi-span frame model to consider, in a simple way, the soil-structure interaction modelled in a finite element scheme. Modeling the three-component wave propagation enables the effects of a soil multiaxial stress state to be taken into account. These reduce soil strength and increase nonlinear effects, compared with the axial stress state. The simultaneous propagation of three components allows the prediction of the incident direction of seismic loading at the ground surface and the analysis of the behavior of a frame structure shaken by a three-component earthquake. A parametric study is carried out to characterize the changes in the ground motion due to dynamic features of the structure, for different incident wavefield properties and soil nonlinear effects. A seismic response depending on parameters such as the frequency content of soil and structur...

  13. Broadband hydroseismograms observed by closed borehole wells in the Kamioka mine, central Japan: Response of pore pressure to seismic waves from 0.05 to 2 Hz

    Science.gov (United States)

    Kano, Yasuyuki; Yanagidani, Takashi

    2006-03-01

    We obtained broadband hydroseismograms by monitoring the pore pressure changes of a rock mass in the Kamioka mine, using borehole wells. The wellhead was sealed to maintain an undrained condition, under which there is no flow of water through the interface between the well and the rock mass. This reduces the wellbore storage effect, which can cause a high-frequency cutoff response for systems of conventional open wells and rock mass. Using these closed borehole wells, 16 hydroseismograms were recorded for earthquakes in a range of magnitudes of 4.5-7.9 and epicentral distances of 1.0°-71.6°. Direct P waves, SV waves converted to P, and Rayleigh phases are clearly observed on the hydroseismograms. The similarity between hydroseismograms and seismograms reveals a clear relationship between radial ground velocity and pore pressure. The relationship is expressed as a zero-order system, which is characterized by no distortion or time lag between the input and output, and the pore pressure has no coupling with shear deformation. These results are consistent with an undrained constitutive relation of linear poroelastic theory and confirm that the relation is valid for the seismic frequency range. We determined in situ values of pore pressure sensitivity to volumetric change of the rock mass, which were then used to estimate in situ Skempton coefficients with values of 0.70-0.85.

  14. Translational head movements of pigeons in response to a rotating pattern: characteristics and tool to analyse mechanisms underlying detection of rotational and translational optical flow.

    Science.gov (United States)

    Nalbach, H O

    1992-01-01

    Pigeons freely standing in the centre of a two-dimensionally textured cylinder not only rotate but also laterally translate their head in response to the pattern sinusoidally oscillating or unidirectionally rotating around their vertical axis. The translational head movement dominates the response at high oscillation frequencies, whereas in a unidirectionally rotating drum head translation declines at about the same rate as the rotational response increases. It is suggested that this is a consequence of charging the 'velocity storage' in the vestibulo-ocular system. Similar to the rotational head movement (opto-collic reflex), the translational head movement is elicited via a wide-field motion sensitive system. The underlying mechanism can be described as vector integration of movement vectors tangential to the pattern rotation. Stimulation of the frontal visual field elicits largest translational responses while rotational responses can be elicited equally well from any azimuthal position of a moving pattern. Experiments where most of the pattern is occluded by a screen and the pigeon is allowed to view the stimulus through one or two windows demonstrate a short-range inhibition and long-range excitation between movement detectors that feed into the rotational system. Furthermore, the results obtained from such types of experiments suggest that the rotational system inhibits the translational system. These mechanisms may help the pigeon to decompose image flow into its translational and rotational components. Because of their translational response to a rotational stimulus, it is concluded, however, that pigeons either generally cannot perfectly perform the task or they need further visual information, like differential image motion, that was not available to them in the paradigms.

  15. Between-Groups Study Designs Demand Between-Groups Analyses: A Response to Hernandez-Reif, Shor-Posner, Baez, Soto, Mendoza, Castillo, Quintero, Perez, and Zhang

    Directory of Open Access Journals (Sweden)

    Christopher A. Moyer

    2009-01-01

    Full Text Available The most recent massage therapy (MT study by Hernandez-Reif et al. displays flaws persistent in this area of research that are attributable to MT researchers’ frequent mistake of using within-group analyses of dependent variables in studies that are purported to be randomized control trials. This practise violates the logic of using randomization to create treatment and control groups, and thereby fails to control for the validity threats of spontaneous remission, placebo effects, and statistical regression. The result is that a clear understanding of what MT can and cannot do is seriously hampered.

  16. Functional analyses of AtCHR12 and AtCHR23 : plant growth responses upon over-expression of chromatin remodeling ATPase genes

    NARCIS (Netherlands)

    Folta, A.

    2015-01-01

    Living organisms have to deal with changing environmental conditions during their whole life cycle. In contrast to animals, plants are sessile organisms. Therefore they have evolved multiple regulatory mechanisms that help them to cope with changing conditions. One of the first responses to stress c

  17. Genome-wide whole blood microRNAome and transcriptome analyses reveal miRNA-mRNA regulated host response to foodborne pathogen Salmonella infection in swine

    Science.gov (United States)

    MicroRNAs (miRNAs) are important regulators of gene expression and play key roles in several biological processes. However, little is known about the role of miRNAs in regulating genes involved in host response to bacterial infection. Here, we present a systematic study of miRNA and mRNA profiles fr...

  18. Re-evaluating a vision-related quality of life questionnaire with item response theory (IRT) and differential item functioning (DIF) analyses.

    NARCIS (Netherlands)

    Nispen, R.M.A. van; Knol, D.L.; Langelaan, M.; Rens, G.H.M.B. van

    2011-01-01

    Background: For the Low Vision Quality Of Life questionnaire (LVQOL) it is unknown whether the psychometric properties are satisfactory when an item response theory (IRT) perspective is considered. This study evaluates some essential psychometric properties of the LVQOL questionnaire in an IRT model

  19. The relationship between zinc intake and serum/plasma zinc concentration in pregnant and lactating women: A systematic review with dose-response meta-analyses

    NARCIS (Netherlands)

    Hall Moran, V.; Skinner, A.L.; Warthon Medina, M.; Patel, S.; Dykes, F.; Souverein, O.W.; Dullemeijer, C.; Lowe, N.M.M.

    2012-01-01

    Recommendations for zinc intake during pregnancy and lactation vary widely across Europe. Using data on zinc intake and biomarkers of zinc status reported in randomized controlled trials (RCTs) and observational studies can provide estimates of dose–response relationships that may be used for underp

  20. Exploring the potential of analysing visual search behaviour data using FROC (free-response receiver operating characteristic) method: an initial study

    Science.gov (United States)

    Dong, Leng; Chen, Yan; Dias, Sarah; Stone, William; Dias, Joseph; Rout, John; Gale, Alastair G.

    2017-03-01

    Visual search techniques and FROC analysis have been widely used in radiology to understand medical image perceptual behaviour and diagnostic performance. The potential of exploiting the advantages of both methodologies is of great interest to medical researchers. In this study, eye tracking data of eight dental practitioners was investigated. The visual search measures and their analyses are considered here. Each participant interpreted 20 dental radiographs which were chosen by an expert dental radiologist. Various eye movement measurements were obtained based on image area of interest (AOI) information. FROC analysis was then carried out by using these eye movement measurements as a direct input source. The performance of FROC methods using different input parameters was tested. The results showed that there were significant differences in FROC measures, based on eye movement data, between groups with different experience levels. Namely, the area under the curve (AUC) score evidenced higher values for experienced group for the measurements of fixation and dwell time. Also, positive correlations were found for AUC scores between the eye movement data conducted FROC and rating based FROC. FROC analysis using eye movement measurements as input variables can act as a potential performance indicator to deliver assessment in medical imaging interpretation and assess training procedures. Visual search data analyses lead to new ways of combining eye movement data and FROC methods to provide an alternative dimension to assess performance and visual search behaviour in the area of medical imaging perceptual tasks.

  1. Interdecadal variations and trends of the Urban Heat Island in Athens (Greece) and its response to heat waves

    Science.gov (United States)

    Founda, D.; Pierros, F.; Petrakis, M.; Zerefos, C.

    2015-07-01

    The study explores the interdecadal and seasonal variability of the urban heat island (UHI) intensity in the city of Athens. Daily air temperature data from a set of urban and surrounding non urban stations over the period 1970-2004 were used. Nighttime and daytime heat island revealed different characteristics as regards the mean amplitude, seasonal variability and temporal variation and trends. The difference of the annual mean air temperature between urban and rural stations exhibited a progressive statistically significant increase over the studied period, with rates equal to + 0.2 °C/decade. A gradual and constant increase of the daytime UHI intensity was detected, in contrast to the nighttime UHI intensity which increases only in summer, after the mid 1980s. UHI phenomenon was found to be related to higher increasing rates of hot days frequency at the urban stations. It was found that the interaction between heat waves and heat island in Athens, results to pronounced amplification of nocturnal UHI intensity under exceptionally hot weather.

  2. Response characteristics of a viscoelastic gel under the co-action of sound waves and an electric field

    Science.gov (United States)

    Tang, Hong; Zhao, Xiaopeng; Wang, Baoxiang; Zhao, Yan

    2006-02-01

    We design a flexible sound tunable sandwiched panel structure, which is composed of a nanoelectrorheological gel layer and two conductive rubber sheets, and experimentally investigate the tunable behaviors of the sound transmitted through the panel. For the frequency range of 380-500 Hz the transmitted sound pressure level (SPL) decreases with the electric field strength Ee, while at about 550-650 Hz the SPL increases with Ee. Within 500-550 Hz a hump appears and the hump apex shifts in the high frequency direction with increase of Ee. Besides this, the phase angle of the transmitted sound wave changes with Ee within these frequency ranges. The weight fraction of particles in the electrorheological gels also influences these observed tunable characteristics. The theoretical calculation based on a vibration-radiation model agrees with the experimental results, qualitatively. It is revealed that the electric field induced viscoelasticity change in the electrorheological gel and hence the vibration-radiation variation on the sandwiched panel is the origin of the phenomenon. The flexible composite electrorheological panel could be used in sound sensitive artificial skins or sound tunable actuators and has potential for use in robots and intelligent structures and systems.

  3. Controlled Low-Pressure Blast-Wave Exposure Causes Distinct Behavioral and Morphological Responses Modelling Mild Traumatic Brain Injury, Post-Traumatic Stress Disorder, and Comorbid Mild Traumatic Brain Injury-Post-Traumatic Stress Disorder.

    Science.gov (United States)

    Zuckerman, Amitai; Ram, Omri; Ifergane, Gal; Matar, Michael A; Sagi, Ram; Ostfeld, Ishay; Hoffman, Jay R; Kaplan, Zeev; Sadot, Oren; Cohen, Hagit

    2017-01-01

    The intense focus in the clinical literature on the mental and neurocognitive sequelae of explosive blast-wave exposure, especially when comorbid with post-traumatic stress-related disorders (PTSD) is justified, and warrants the design of translationally valid animal studies to provide valid complementary basic data. We employed a controlled experimental blast-wave paradigm in which unanesthetized animals were exposed to visual, auditory, olfactory, and tactile effects of an explosive blast-wave produced by exploding a thin copper wire. By combining cognitive-behavioral paradigms and ex vivo brain MRI to assess mild traumatic brain injury (mTBI) phenotype with a validated behavioral model for PTSD, complemented by morphological assessments, this study sought to examine our ability to evaluate the biobehavioral effects of low-intensity blast overpressure on rats, in a translationally valid manner. There were no significant differences between blast- and sham-exposed rats on motor coordination and strength, or sensory function. Whereas most male rats exposed to the blast-wave displayed normal behavioral and cognitive responses, 23.6% of the rats displayed a significant retardation of spatial learning acquisition, fulfilling criteria for mTBI-like responses. In addition, 5.4% of the blast-exposed animals displayed an extreme response in the behavioral tasks used to define PTSD-like criteria, whereas 10.9% of the rats developed both long-lasting and progressively worsening behavioral and cognitive "symptoms," suggesting comorbid PTSD-mTBI-like behavioral and cognitive response patterns. Neither group displayed changes on MRI. Exposure to experimental blast-wave elicited distinct behavioral and morphological responses modelling mTBI-like, PTSD-like, and comorbid mTBI-PTSD-like responses. This experimental animal model can be a useful tool for elucidating neurobiological mechanisms underlying the effects of blast-wave-induced mTBI and PTSD and comorbid mTBI-PTSD.

  4. Comparative physiogenomic analyses of weight loss in response to 2 modes of bariatric surgery: demonstration with candidate neuropsychiatric and cardiometabolic genes.

    Science.gov (United States)

    Seip, Richard L; Papasavas, Pavlos; Stone, Andrea; Thompson, Stephen; Ng, Janet; Tishler, Darren S; Ruaño, Gualberto

    2016-02-01

    Surgical weight loss response is variable, with suboptimal outcomes in some patients. We hypothesized that genetic biomarkers may be related to weight change. We tested 330 single nucleotide polymorphisms (SNPs) in genes relevant to metabolic regulation in 161 patients whose decrease in body mass index (BMI), 1 year after laparoscopic adjustable gastric banding (LAGB) or Roux-en-Y gastric bypass (RYGB), was small (lowest quartile response) or large (highest quartile response). LAGB patients whose BMI decreased≤4.7 or≥10.2 units comprised groups I (n = 43) and II (n = 40), respectively. RYGB patients whose BMI decreased≤13.6 or≥19.8 units comprised groups III (n = 39) and IV (n = 39), respectively. Within each surgery, SNPs with large differences in reference allele frequency (z score>2, corresponding to values displaced 2 standard deviations [SD] from the mean for all SNPs) in low versus high quartiles, were identified. We compared reference allele frequencies, within surgical procedure, using the χ(2) test (using Bonferroni correction for multiple testing). The mean percent excess weight losses (±SD) corresponding to groups I, II, III, and IV were: 16 (±12), 64 (±30), 55 (±16), and 75 (±17), respectively. SNPs with z score>2 were identified in genes involved in LAGB response, lipid metabolic regulation (APOE, rs439401; APOC4, rs2288911), neural processes (DRD3, rs167771; HTR3 B, rs3758987), and xeno- or endobiotic metabolism (CYP3 A4, rs12333983); and for RYGB response, in lipid transport (SCARB1, rs10846744), folate metabolism (MTHFR, rs2066470), regulation of glycolysis in immune cells (HIF1 A, rs1951795), vitamin K cycling (VKORC1, rs2359612), and xeno- or endobiotic metabolism (CYP3 A4, rs2242480). For LAGB response, APOE SNP frequencies were significantly different. With further validation, information derived from patient DNA may be useful to predict surgical weight loss outcomes and guide selection of surgical approach. Copyright © 2016

  5. Spectral characteristics of the nearshore waves off Paradip, India during monsoon and extreme events

    Digital Repository Service at National Institute of Oceanography (India)

    Aboobacker, V.M.; Vethamony, P.; Sudheesh, K.; Rupali, S.P.

    Spectral and statistical wave parameters obtained from the measured time series wave data off Paradip, east coast of India during May 1996-January 1997 were analysed along with MIKE 21 spectral wave model (SW) results. Statistical wave parameters...

  6. Design Process of IDT Aided by Multiphysics FE Analyses

    Directory of Open Access Journals (Sweden)

    A Martowicz

    2016-09-01

    Full Text Available Presented work is devoted to a design process performed for the interdigital transducer, which is a perspective application for the area of structural health monitoring. In order to obtain the desirable characteristic of the transducer fully coupled numerical analyses were performed in ANSYS Multiphysics software. Utilised finite element models considered both structural dynamics and properties of used piezoelectric material. The process of design improvement was preceded by the sensitivity analysis. In order to search for the best electrode pattern selected geometrical features of the transducer were assumed to vary within allowed ranges. The design parameters, which were taken into account, related to the efficiency of proposed transducer design for the emission of acoustic waves in the monitored structure. The search objectives considered the criteria related to the shape of the beampattern and amplitudes of generated Lamb waves. As a result of the optimization procedure, the simultaneous increase of anti-symmetric mode amplitude and the reduction of undesirable symmetric mode amplitude of generated Lamb waves in the direction perpendicular to the transducer fingers was expected. Another aim of the optimization was to minimize the main lobe width and undesirable contribution of both symmetric and anti-symmetric waves in the parallel direction to the transducer fingers. The response surface method and genetic algorithms were used for fast and effective search through the input design domain.

  7. The stationary wave response to a midlatitude SST anomaly in an idealized GCM. [SST (sea surface temperature); GCM (general circulation model)

    Energy Technology Data Exchange (ETDEWEB)

    Ting, M. (Univ. of Colorado, Boulder, CO (United States))

    1991-05-15

    The atmospheric stationary wave response to a midlatitude sea surface temperature (SST) anomaly is examined with an idealized general circulation model (GCM) as well as steady linear model, in a similar way as Ting and Held, for a tropical SST anomaly. The control climate of the GCM is zonally symmetric; this symmetric climate is then perturbed by a monopole SST anomaly centered at 40[degrees]N. Two experiments, with SST anomalies of opposite sign, have been conducted. The stationary response is roughly linear in the sign of the SST anomaly, despite the fact that precipitation shows strong nonlinearity. The linear model, which is in exact linearization of the GCM equations in use, when forced by anomalous heating and transients, reproduces the GCM's stationary response excellently. The low-level transient eddy heat fluxes act to damp the lower level temperature signal. When this damping effect is mimicked by a horizontal thermal diffusion in the linear model, the response to the diabatic heating alone gives a reasonably good simulation of the GCm's anomaly; the effect of the anomalous transient momentum fluxes is relatively small. A crude latent heat parameterization scheme, using an evaporation anomaly that is proportional to the mean air-sea surface moisture difference and including the effects of mean moisture advection, is developed. When the perturbation mixing ratio is approximated by assuming fixed relative humidity and by linearizing the Clausius-Clapeyron equation, the linear model's response, utilizing this latent heat parameterization scheme, gives a useful fit to the GCM's anomalous flow. 22 refs., 94 figs.

  8. Functional analyses of AtCHR12 and AtCHR23 : plant growth responses upon over-expression of chromatin remodeling ATPase genes

    OpenAIRE

    Folta, A.

    2015-01-01

    Living organisms have to deal with changing environmental conditions during their whole life cycle. In contrast to animals, plants are sessile organisms. Therefore they have evolved multiple regulatory mechanisms that help them to cope with changing conditions. One of the first responses to stress conditions is reduction or arrest of growth. Therefore regulation of growth and development is essential to successfully complete their life cycle. To correctly time their development, plants need t...

  9. Systematic review using meta-analyses to estimate dose-response relationships between iodine intake and biomarkers of iodine status in different population groups.

    Science.gov (United States)

    Ristić-Medić, Danijela; Dullemeijer, Carla; Tepsić, Jasna; Petrović-Oggiano, Gordana; Popović, Tamara; Arsić, Aleksandra; Glibetić, Marija; Souverein, Olga W; Collings, Rachel; Cavelaars, Adriënne; de Groot, Lisette; van't Veer, Pieter; Gurinović, Mirjana

    2014-03-01

    The objective of this systematic review was to identify studies investigating iodine intake and biomarkers of iodine status, to assess the data of the selected studies, and to estimate dose-response relationships using meta-analysis. All randomized controlled trials, prospective cohort studies, nested case-control studies, and cross-sectional studies that supplied or measured dietary iodine and measured iodine biomarkers were included. The overall pooled regression coefficient (β) and the standard error of β were calculated by random-effects meta-analysis on a double-log scale, using the calculated intake-status regression coefficient (β) for each individual study. The results of pooled randomized controlled trials indicated that the doubling of dietary iodine intake increased urinary iodine concentrations by 14% in children and adolescents, by 57% in adults and the elderly, and by 81% in pregnant women. The dose-response relationship between iodine intake and biomarkers of iodine status indicated a 12% decrease in thyroid-stimulating hormone and a 31% decrease in thyroglobulin in pregnant women. The model of dose-response quantification used to describe the relationship between iodine intake and biomarkers of iodine status may be useful for providing complementary evidence to support recommendations for iodine intake in different population groups.

  10. On the generation of internal wave modes by surface waves

    Science.gov (United States)

    Harlander, Uwe; Kirschner, Ian; Maas, Christian; Zaussinger, Florian

    2016-04-01

    Internal gravity waves play an important role in the ocean since they transport energy and momentum and the can lead to mixing when they break. Surface waves and internal gravity waves can interact. On the one hand, long internal waves imply a slow varying shear current that modifies the propagation of surface waves. Surface waves generated by the atmosphere can, on the other hand, excite internal waves by nonlinear interaction. Thereby a surface wave packet consisting of two close frequencies can resonate with a low frequency internal wave (Phillips, 1966). From a theoretical point of view, the latter has been studied intensively by using a 2-layer model, i.e. a surface layer with a strong density contrast and an internal layer with a comparable weak density contrast (Ball, 1964; Craig et al., 2010). In the present work we analyse the wave coupling for a continuously stratified fluid using a fully non-linear 2D numerical model (OpenFoam) and compare this with laboratory experiments (see Lewis et al. 1974). Surface wave modes are used as initial condition and the time development of the dominant surface and internal waves are studied by spectral and harmonic analysis. For the simple geometry of a box, the results are compared with analytical spectra of surface and gravity waves. Ball, F.K. 1964: Energy transfer between external and internal gravity waves. J. Fluid Mech. 19, 465. Craig, W., Guyenne, P., Sulem, C. 2010: Coupling between internal and surface waves. Natural Hazards 57, 617-642. Lewis, J.E., Lake, B.M., Ko, D.R.S 1974: On the interaction of internal waves and surfacr gravity waves, J. Fluid Mech. 63, 773-800. Phillips, O.M. 1966: The dynamics of the upper ocean, Cambridge University Press, 336pp.

  11. Broad blockade antibody responses in human volunteers after immunization with a multivalent norovirus VLP candidate vaccine: immunological analyses from a phase I clinical trial.

    Directory of Open Access Journals (Sweden)

    Lisa C Lindesmith

    2015-03-01

    Full Text Available Human noroviruses (NoVs are the primary cause of acute gastroenteritis and are characterized by antigenic variation between genogroups and genotypes and antigenic drift of strains within the predominant GII.4 genotype. In the context of this diversity, an effective NoV vaccine must elicit broadly protective immunity. We used an antibody (Ab binding blockade assay to measure the potential cross-strain protection provided by a multivalent NoV virus-like particle (VLP candidate vaccine in human volunteers.Sera from ten human volunteers immunized with a multivalent NoV VLP vaccine (genotypes GI.1/GII.4 were analyzed for IgG and Ab blockade of VLP interaction with carbohydrate ligand, a potential correlate of protective immunity to NoV infection and illness. Immunization resulted in rapid rises in IgG and blockade Ab titers against both vaccine components and additional VLPs representing diverse strains and genotypes not represented in the vaccine. Importantly, vaccination induced blockade Ab to two novel GII.4 strains not in circulation at the time of vaccination or sample collection. GII.4 cross-reactive blockade Ab titers were more potent than responses against non-GII.4 VLPs, suggesting that previous exposure history to this dominant circulating genotype may impact the vaccine Ab response. Further, antigenic cartography indicated that vaccination preferentially activated preexisting Ab responses to epitopes associated with GII.4.1997. Study interpretations may be limited by the relevance of the surrogate neutralization assay and the number of immunized participants evaluated.Vaccination with a multivalent NoV VLP vaccine induces a broadly blocking Ab response to multiple epitopes within vaccine and non-vaccine NoV strains and to novel antigenic variants not yet circulating at the time of vaccination. These data reveal new information about complex NoV immune responses to both natural exposure and to vaccination, and support the potential

  12. Plasma waves

    CERN Document Server

    Swanson, DG

    1989-01-01

    Plasma Waves discusses the basic development and equations for the many aspects of plasma waves. The book is organized into two major parts, examining both linear and nonlinear plasma waves in the eight chapters it encompasses. After briefly discussing the properties and applications of plasma wave, the book goes on examining the wave types in a cold, magnetized plasma and the general forms of the dispersion relation that characterize the waves and label the various types of solutions. Chapters 3 and 4 analyze the acoustic phenomena through the fluid model of plasma and the kinetic effects. Th

  13. Experiments on the WavePiston, Wave Energy Converter

    DEFF Research Database (Denmark)

    Angelelli, E.; Zanuttigh, B.; Kofoed, Jens Peter

    2011-01-01

    This paper analyses the performance of a new Wave Energy Converter (WEC) of the Oscillating Water Column type (OWC), named WavePiston. This near-shore floating device is composed of plates (i.e. energy collectors) sliding around a cylinder, that is placed perpendicular to the shore. Tests...

  14. Roadway dynamic response analysis under mining rockburst condition

    Energy Technology Data Exchange (ETDEWEB)

    Chun-rui Li; Qing-xin Qi; Jun-feng Pan; Hang Lan [China Coal Research Institute, Beijing (China). Mining Design and Research Institute

    2009-09-15

    In order to determine how a roadway withstands a momentum wave and determine the extent of damage to rock surrounding the roadway under different force wave peak impacts, the roadway dynamic response state was analysed using numerical simulation method. The roadway's critical peak force wave and fracture region under dynamic wave action were put forward. It is concluded that the method has practical value to roadway support and rockburst prevention.The article is based on the anaysis of Xinwen Mining Group's geologic condition of Xiezhuang 4-2 mine. 4 refs., 4 figs., 1 tab.

  15. The tuition fee ‘shock’: Analysing the response of first-year students to a spatially discontinuous policy change in Germany

    DEFF Research Database (Denmark)

    Mitze, Timo Friedel; Burgard, Claudia; Alecke, Björn

    2015-01-01

    variation in tuition fee regimes as a result of a Federal Constitutional Court decision. Our empirical results show that the introduction of tuition fees had a particular impact on student migration. We observe three effects: first, male students show a stronger migration response compared to female...... students. Second, changes in migration behaviour are sensitive to geographical distance. Finally, comparing different types of higher education institutions, we find that the migration effect is larger for universities compared to technical colleges and colleges of arts or music....

  16. The tuition fee ‘shock’: Analysing the response of first-year students to a spatially discontinuous policy change in Germany

    DEFF Research Database (Denmark)

    Mitze, Timo Friedel; Burgard, Claudia; Alecke, Björn

    2015-01-01

    variation in tuition fee regimes as a result of a Federal Constitutional Court decision. Our empirical results show that the introduction of tuition fees had a particular impact on student migration. We observe three effects: first, male students show a stronger migration response compared to female...... students. Second, changes in migration behaviour are sensitive to geographical distance. Finally, comparing different types of higher education institutions, we find that the migration effect is larger for universities compared to technical colleges and colleges of arts or music....

  17. Genome-wide identification, phylogeny, and expression analyses of the 14-3-3 family reveal their involvement in the development, ripening and abiotic stress response in banana

    Directory of Open Access Journals (Sweden)

    meiying li

    2016-09-01

    Full Text Available Plant 14-3-3 proteins act as critical components of various cellular signaling processes and play an important role in regulating multiple physiological processes. However, less information is known about the 14-3-3 gene family in banana. In this study, 25 14-3-3 genes were identified from the banana genome. Based on the evolutionary analysis, banana 14-3-3 proteins were clustered into ε and non-ε groups. Conserved motif analysis showed that all identified banana 14-3-3 genes had the typical 14-3-3 motif. The gene structure of banana 14-3-3 genes showed distinct class-specific divergence between the ε group and the non-ε group. Most banana 14-3-3 genes showed strong transcript accumulation changes during fruit development and postharvest ripening in two banana varieties, indicating that they might be involved in regulating fruit development and ripening. Moreover, some 14-3-3 genes also showed great changes after osmotic, cold, and salt treatments in two banana varieties, suggested their potential role in regulating banana response to abiotic stress. Taken together, this systemic analysis reveals the involvement of banana 14-3-3 genes in fruit development, postharvest ripening, and response to abiotic stress and provides useful information for understanding the functions of 14-3-3 genes in banana.

  18. Comparative Analyses of Response Surface Methodology and Artificial Neural Network on Medium Optimization for Tetraselmis sp. FTC209 Grown under Mixotrophic Condition

    Directory of Open Access Journals (Sweden)

    Mohd Shamzi Mohamed

    2013-01-01

    Full Text Available Mixotrophic metabolism was evaluated as an option to augment the growth and lipid production of marine microalga Tetraselmis sp. FTC 209. In this study, a five-level three-factor central composite design (CCD was implemented in order to enrich the W-30 algal growth medium. Response surface methodology (RSM was employed to model the effect of three medium variables, that is, glucose (organic C source, NaNO3 (primary N source, and yeast extract (supplementary N, amino acids, and vitamins on biomass concentration, Xmax, and lipid yield, Pmax/Xmax. RSM capability was also weighed against an artificial neural network (ANN approach for predicting a composition that would result in maximum lipid productivity, Prlipid. A quadratic regression from RSM and a Levenberg-Marquardt trained ANN network composed of 10 hidden neurons eventually produced comparable results, albeit ANN formulation was observed to yield higher values of response outputs. Finalized glucose (24.05 g/L, NaNO3 (4.70 g/L, and yeast extract (0.93 g/L concentration, affected an increase of Xmax to 12.38 g/L and lipid a accumulation of 195.77 mg/g dcw. This contributed to a lipid productivity of 173.11 mg/L per day in the course of two-week cultivation.

  19. Genome-wide whole blood microRNAome and transcriptome analyses reveal miRNA-mRNA regulated host response to foodborne pathogen Salmonella infection in swine.

    Science.gov (United States)

    Bao, Hua; Kommadath, Arun; Liang, Guanxiang; Sun, Xu; Arantes, Adriano S; Tuggle, Christopher K; Bearson, Shawn M D; Plastow, Graham S; Stothard, Paul; Guan, Le Luo

    2015-07-31

    To understand the role of miRNAs in regulating genes involved in host response to bacterial infection and shedding of foodborne pathogens, a systematic profiling of miRNAs and mRNAs from the whole blood of pigs upon Salmonella challenge was performed. A total of 62 miRNAs were differentially expressed post infection (false discovery rate Salmonella infection. From these networks, miR-214 and miR-331-3p were identified as new candidates potentially associated with Salmonella infection. An miRNA seed sequence analysis suggested that these miRNAs regulate several critical immune-related genes including SLC11A1, PIGE-108A11.3 and VAV2. We showed that challenged pigs had reduced miR-214 expression and increased miR-331-3p expression in the whole blood. Furthermore, the expression of the proposed targets of miR-214 (SLC11A1 and PIGE-108A11.3) increased while that of the proposed target of miR-331-3p (VAV2) decreased following challenge (expression changes confirmed by in vitro assays). Based on these observations, we propose potential roles for miR-214 and miR-331-3p in regulation of immune responses to Salmonella infection.

  20. Genome-Wide Identification, Phylogeny, and Expression Analyses of the 14-3-3 Family Reveal Their Involvement in the Development, Ripening, and Abiotic Stress Response in Banana

    Science.gov (United States)

    Li, Meiying; Ren, Licheng; Xu, Biyu; Yang, Xiaoliang; Xia, Qiyu; He, Pingping; Xiao, Susheng; Guo, Anping; Hu, Wei; Jin, Zhiqiang

    2016-01-01

    Plant 14-3-3 proteins act as critical components of various cellular signaling processes and play an important role in regulating multiple physiological processes. However, less information is known about the 14-3-3 gene family in banana. In this study, 25 14-3-3 genes were identified from the banana genome. Based on the evolutionary analysis, banana 14-3-3 proteins were clustered into ε and non-ε groups. Conserved motif analysis showed that all identified banana 14-3-3 genes had the typical 14-3-3 motif. The gene structure of banana 14-3-3 genes showed distinct class-specific divergence between the ε group and the non-ε group. Most banana 14-3-3 genes showed strong transcript accumulation changes during fruit development and postharvest ripening in two banana varieties, indicating that they might be involved in regulating fruit development and ripening. Moreover, some 14-3-3 genes also showed great changes after osmotic, cold, and salt treatments in two banana varieties, suggested their potential role in regulating banana response to abiotic stress. Taken together, this systemic analysis reveals the involvement of banana 14-3-3 genes in fruit development, postharvest ripening, and response to abiotic stress and provides useful information for understanding the functions of 14-3-3 genes in banana. PMID:27713761