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Sample records for wang qing jiao

  1. Honggang Wang

    Indian Academy of Sciences (India)

    Honggang Wang. Articles written in Journal of Genetics. Volume 90 Issue 3 December 2011 pp 409-425 Research Article. Wheat kernel dimensions: how do they contribute to kernel weight at an individual QTL level? Fa Cui Anming Ding Jun Li Chunhua Zhao Xingfeng Li Deshun Feng Xiuqin Wang Lin Wang Jurong Gao ...

  2. Wang-Landau Without Binning

    Science.gov (United States)

    Brown, G.; Nicholson, D.; Odbadrakh, Kh.; Eisenbach, M.; Rusanu, A.

    2012-02-01

    Results are presented for Wang-Landau calculations on a Heisenberg model of BCC Fe that describe the density of states as function defined for all accessible energies instead of a function tabulated at discrete values of the energy. The density of states function described here is an analytic result valid near the ground state supplemented by a polynomial expansion. The probability density of Wang-Landau random walkers is sampled for a fixed density of states, and that probability density can be used to improve the estimated density of states. Methods for evaluating the convergence of the density of states are discussed along with the diffusion behavior of the random walkers. This work was performed at the Oak Ridge National Laboratory, which is managed by UT-Battelle, LLC under Contract No. DE-AC05-00OR22725, and sponsored by the Laboratory Directed Research and Development Program (ORNL), by the Mathematical, Information, and Computational Sciences Division; Office of Advanced Scientific Computing Research (US DOE), and by the Division of Materials Sciences and Engineering; Office of Basic Energy Sciences (US DOE). Computer resources provided by Florida State University.

  3. Such Stuff as Qing Borderlands are Made On

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    David A. Bello

    2017-06-01

    Full Text Available Kwangmin Kim. Borderland Capitalism: Turkestan Produce, Qing Silver, and the Birth of an Eastern Market. Stanford, CA: Stanford University Press, 2016. 299 pp. $65 (cloth. Jonathan Schlesinger. A World Trimmed with Fur: Wild Things, Pristine Places, and the Natural Fringes of Qing Rule. Stanford, CA: Stanford University Press, 2017. 271 pp. $65 (cloth. The titular stuffs, silver and fur, of the two books reviewed here reveal the material basis of the books’ arguments. Nevertheless, the primary resources exploited directly by authors Kwangmin Kim and Jonathan Schlesinger were the ink and paper of the archival documents in languages other than Chinese, most especially in Manchu, that they consulted in the course of their research. In these books’ reliance on non-Chinese sources, Borderland Capitalism and A World Trimmed with Fur are representative of a growing body of Qing scholarship in English that delineates the empire within multilingual parameters that do not marginalize its borderlands. Instead, in these works, borderlands are integrated with central concerns of imperial commerce and imperial identity, as well as linked solidly to pervasive global trade patterns stretching well beyond the already-vast bounds of the Qing Empire. This reorientation is made possible largely because detailed documentation of local borderland dynamics exists, largely in Manchu, for periods of their formation, consolidation, and onset of decline from the mid-seventeenth into the early nineteenth centuries...

  4. Generation of electron beams from a laser-based advanced accelerator at Shanghai Jiao Tong University

    CERN Document Server

    Elsied, Ahmed M M; Li, Song; Mirzaie, Mohammad; Sokollik, Thomas; Zhang, Jie

    2014-01-01

    At Shanghai Jiao Tong University, we have established a research laboratory for advanced acceleration research based on high-power lasers and plasma technologies. In a primary experiment based on the laser wakefield acceleration (LWFA) scheme, multi-hundred MeV electron beams having a reasonable quality are generated using 20-40 TW, 30 femtosecond laser pulses interacting independently with helium, neon, nitrogen and argon gas jet targets. The laser-plasma interaction conditions are optimized for stabilizing the electron beam generation from each type of gas. The electron beam pointing angle stability and divergence angle as well as the energy spectra from each gas jet are measured and compared.

  5. Qing Re Liang Xue Decoction Alleviates Hypercoagulability in Kawasaki Disease

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    Jiao-yang Chen

    2015-01-01

    Full Text Available Objective. Kawasaki disease (KD is a multisystemic autoimmune vasculitis. Intravenous immunoglobulin (IVIG is the first-line treatment for KD. It is unclear whether traditional Chinese medicine (TCM has an effect on KD. We aimed to observe the clinical efficacy of TCM on acute KD via serum interleukin-33 (IL-33 and tumor necrosis factor alpha (TNF-α measurements. Methods. Thirty-one KD patients were treated with Qing Re Liang Xue decoction and Western medicine (integrative medicine treatment group, while 28 KD patients were treated with Western medicine only (Western medicine treatment group. Thirty patients were included in a febrile group and 28 healthy children were included in the control group. Clinical characteristics and laboratory findings were gathered and compared. Serum IL-33 and TNF-α levels were measured by multiplex Luminex assay. Results. The platelet count in the integrative medicine treatment group was significantly lower than that in the Western medicine treatment group. The integrative medicine group had a shorter fever duration and lower IL-33 and TNF-α levels than those in the Western medicine group, but there were no significant differences between the two KD groups after treatment. Conclusion. Qing Re Liang Xue decoction improved the hypercoagulable state of KD patients. Potential myocardial protective effects require further research.

  6. [Effects of Pogostemon cablin on gastrointestinal function of rats with syndrome of damp retention in middle-jiao].

    Science.gov (United States)

    Xu, Wen; Wang, Nan; Ding, Hao-Ran; Xu, Jing-Jing; Qu, Yi-Hui; Pu, Dan; Xiu, Yan-Feng

    2017-12-01

    To investigate the effects of Pogostemon cablin(patchouli) on gastrointestinal function of rats with the syndrome of damp retention in middle-jiao, and explore its therapeutic mechanism. In this study, gastrointestinal function of rats with the syndrome of damp retention in middle-jiao was evaluated by multiple assays including gastric remnant rate, small intestine propelling rate, gastric juice quantity, pepsin activity and gastrointestinal tissue morphology. ELISA was used to detect gastrointestinal hormones including MTL, GAS, VIP and cytokines including TNF-α and interleukin 10 in rat serum. Real-time fluorescent quantitative PCR technique was used to detect relative mRNA expression of AQP3, AQP4 and AQP8 in gastric and colonic tissues to explore the mechanism of P. cablin in treatment of gastrointestinal functions. The results showed that middle and high dose of P. cablin (3.24, 6.48 g•kg⁻¹) could obviously decrease the gastric remnant rate, promote gastric emptying, increase the small intestine propelling rate(Pdamp retention in middle-jiao. The results of the study laid a foundation for clarifying the treatment mechanism of aromatic damp-resolving drugs for indications including damp retention in middle-jiao and transformation failure of spleen. Copyright© by the Chinese Pharmaceutical Association.

  7. Qing-Qi Rickshaw : A Boon Or Bane For Public Transportation? A Study Of Road Traffic Injury Patterns Involving Qing-Qi Rickshaws In Karachi Pakistan.

    Science.gov (United States)

    Muzzammil, Muhammad; Minhas, Muhammad Saeed; Effendi, Jahanzeb; Jahanzeb, Syed; Mughal, Ayesha; Qadir, Abdul

    2017-01-01

    The three-wheeler Qing-qi and Compressed Natural Gas (CNG) auto-rickshaws were introduced in Karachi to meet the transportation demand of the growing population. These vehicles have directly or indirectly been implicated in a number of road traffic violations as well as road accidents. This study aims to describe the crash characteristics and injury patterns for Qing-qi rickshaw occupants and other road users hit by Qing-qi rickshaw in Karachi, Pakistan. An Observational/ Descriptive study was conducted at Accident & Emergency and Orthopaedic Surgery Department, Jinnah Post Graduate Medical Centre, Karachi Pakistan from July 2014 to June 2015.All patients who came with Qing-qi rickshaw accident in Accident & Emergency (A&E) of JPMC were included. Crash characteristics, details of injuries, injury severity parameters and outcome were documented in detailed interviews. Four hundred and eighty-six rickshaw related injuries were noted in road traffic accidents by Qing-gi rickshaw. Age range was 2-85 (43.5±58.68). 350 injured victims were males and 136 were females. By occupation most victims were laborers and daily wage workers (45%) and students (21%). Overloading of vehicle with more than two passengers was found in (28.5%). The most common cause of injury was collision with a moving vehicle (56%), followed by fall from rickshaw. The most common contributing factor was the overloading of rickshaw and roll over on turning (61%). Injury severity on arrival were mild (49%), moderate were (32%), and severe were (19%). Injuries related to head and neck (26%), face (14%), thorax and abdomen (5%), lower extremity and pelvic girdle (31%) and upper extremity (23%) were observed. Qing-qi rickshaw injuries are common and these vehicles are vulnerable to road traffic accidents. Occupants and road users are both at risk of injuries.

  8. Jiao Tai Wan Attenuates Hepatic Lipid Accumulation in Type 2 Diabetes Mellitus

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    Zhaoyi Huang

    2013-01-01

    Full Text Available Jiao Tai Wan (JTW, a Chinese herbal formula containing Rhizoma Coptidis and Cortex Cinnamomi, has been used for diabetic treatment for many years. The aim of this study was to determine the main components in JTW and to investigate the effects of JTW on hepatic lipid accumulation in diabetic rats and humans. JTW extract was prepared and the main components were assayed by HPLC. An animal model of diabetes mellitus was established and JTW was administered intragastrically. In the clinical study, diabetic patients with poor glycemic control were treated with JTW. Blood glucose and lipid parameters, liver histology, hepatic triglyceride content and lipogenic gene expression were examined. Our data demonstrated that JTW significantly improved hyperglycemia, hyperlipidemia and hepatic lipid accumulation in diabetic rats. This was accompanied by the down-regulation of acetyl coenzyme A carboxylase (ACC and fatty acid synthase (FAS protein expressions, and the up-regulation of AMP-activated protein kinase (AMPK and phosphorylated-ACC (pACC protein expressions in the liver tissues. Diabetic patients also exhibited decreases in their hepatic triglyceride content. The results suggest that JTW attenuates hepatic lipid accumulation in diabetic rats and humans. These beneficial effects are possibly associated with the inhibition of lipogenic gene expression in the liver.

  9. Effects of Chinese Materia Medica-Fubao Danggui Jiao on experimental endometriosis.

    Science.gov (United States)

    Sun, Xing; Chen, Lijue; Zeng, Fanbo

    2011-01-01

    The objective of this paper was to investigate the effects of a Chinese Materia Medica variant -Fubao Danggui Jiao (FDJ)-on experimental endometriosis. An endometriosis model was created by virtue of auto-transplantation of endometrial tissue onto rats' abdominal walls. The implants were allowed to grow for 30 days until the successful completion of the model. After that, forty endometriotic rats were randomly divided into four study groups and given different treatments: (1) negative control group (water, 2ml/kg, per os); (2) FDJ-A group (FDJ, 2ml/kg, per os); (3) FDJ-B group (FDJ, 4ml/kg, per os); (4) Danazol group (70mg/kg, per os). After 30 days with treatments, the volumes of endometriotic implants in each rat were measured. The implants and normal uterine horns were removed for routine histological examination. FDJ caused significant decreases in volumes of the surviving endometriotic implants, with two different doses having statistically equivalent effects. Upon histological examination, FDJ was observed to cause regression of epithelium and stroma of endometriotic implants. FDJ had revealed promising therapeutic effects on endometriosis.

  10. The Changing Representation of the Late Qing History in Chinese Film

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    Guo Wu

    2010-10-01

    Full Text Available From the 1950s to the 1990s, Chinese film never ceased to represent the turbulent late Qing history on the screen. The representations, all carrying the mark of their own time, not only tell a story about the late Qing Chinese predicament and dilemma of its modernization, but also reveal the trajectory of the changing ideologies behind their own production. In this sense, the films can be read as both historical and contemporary texts. This article attempts to trace the changing representation by comparing and analyzing major historical films of China from the 1950s to the 1990s, and focuses the discussion on several main themes.

  11. Changming Wang - Journal of Earth System Science | Indian ...

    Indian Academy of Sciences (India)

    Volume 125 Issue 3 April 2016 pp 585-603. Petrogenesis, zircon U–Pb age, and geochemistry of the A-type Mogou syenite, western Henan Province: Implications for Mesozoic tectono-magmatic evolution of the Qinling Orogen · Xinyu He Jionghui Wang Changming Wang Emmanuel John M Carranza Liang Chen Bin Wu.

  12. Human Capital in Qing China: Economic Determinism or a History of Failed Opportunities?

    NARCIS (Netherlands)

    Xu, Y.; Foldvari, P.; van Leeuwen, B.

    2014-01-01

    The traditional education system in Qing China has been widely debated over the past decades. Some have argued it was efficient and furthered economic growth, while others have stressed its inefficient nature, which led to the introduction of the modern education system in the closing decades of the

  13. The Rise of Women's Modern Schooling in Late Qing China (1840-1911)

    Science.gov (United States)

    Liu, Xiaoyi

    2009-01-01

    The rise of women's modern schooling in late Qing China was deemed to be, by the historical trend of modern China, a progress that coincided with China's modernization and national self-strengthening movement after the humiliating defeat of the Opium War. This article is an examination of this process from 1840 to 1911, which had undergone three…

  14. Hunchun, the Qing-Chosŏn Borderland in the Eighteenth Century

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    Seonmin Kim

    2016-02-01

    Full Text Available Based on a murder which emerged near Hunchun in 1749, this study analyzes the varied and complex nature of the Qing-Chosŏn relationship. The local residents residing along the border, local officials guarding the border between both countries, and the Qing emperor and Chosŏn king were all involved in this murder in which Qing subjects were killed by Chosŏn people along the Tumen River. However, this incident was differently perceived in the Tumen River area, Hunchun, Beijing and Seoul, depending on the positions of those who were involved with. The Qing emperor in Beijing and Chosŏn king in Seoul saw the Tumen and Yalu Rivers as an implement to ensure the authority of the suzerain court and the loyalty of tributary court. The control of borders and punishment of trespassers were important elements of the power of the Qing emperor and Chosŏn king. For the residents of this area, the Tumen River area was a trading space in which articles could be purchased based on contacts; meanwhile, for local officials, it was an area in which close cooperation with the officials from the adjacent country was needed in order to implement the orders of the central government. For local residents and officials, the Tumen River was as such a detailed and physical space rather than an abstract and political line. Rather than a space in which the will of the central power was unilaterally conveyed and penetrated, the borderland known as the Tumen River and Hunchun was a space in which various classes of people expressed and negotiated their desires.

  15. Chemical gas-dynamics beyond Wang Chang-Uhlenbeck's kinetics

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    Kolesnichenko, Evgeniy G.; Gorbachev, Yuriy E.

    2014-12-01

    Wang Chang-Uhlenbeck equation does not give possibility to take into account intermolecular processes such as redistribution of the energy among different degrees of freedom. The modification of the generalized Wang Chang-Uhlenbeck equation including such processes is proposed. It allows to study for instance the kinetics of non-radiative transitions. Limitations of this approach are connected with the requirements of absence of polarization of rotational momentum and phases of intermolecular vibrations.

  16. Renewable Energy in China: Xiao Qing Dao Village Power Wind/Diesel Hybrid Pilot Project

    Energy Technology Data Exchange (ETDEWEB)

    2006-01-01

    In 2000, DOE/NREL and the State Power Corporation of China (SPCC) developed a pilot project to electrify Xiao Qing Dao, a small island located in China's Yellow Sea. The project demonstrates the practicality of renewable energy systems for medium-scale, off-grid applications. It consists of four 10 k-W wind turbines connected to a 30-kW diesel generator, a 40-kW inverter and a battery bank.

  17. Rulers and rascals : the politics of gold mining in Mongolian Qing history

    OpenAIRE

    High, Mette; Schlesinger, Jonathan

    2010-01-01

    M1 - Article This article examines the politics of gold mining in the Mongolian cultural region during the Qing period and today. By drawing on archival material and accounts by travellers of the period, the authors situate the current mining boom within its greater historical context. Since the exploration of gold has been surrounded by enduring notions of exclusivity and purity, the article shows how mining for gold has historically been closely related to Mongolian practices of politica...

  18. WANG TILE SIZE IN TERMS OF CIRCULAR PARTICLE DYNAMICS

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    David Šedlbauer

    2017-11-01

    Full Text Available The main advantage of the Wang tiling concept for material engineering is ability to create large material domains with a relatively small set of tiles. Such idea allows both a reduction of computational demands and preserving heterogeneity of a reconstructed media in comparison with traditional cell concepts. This work is dealing with a random heterogeneous material composed of monodisperse circular hard particles within a matrix. The Wang tile sets are generated via algorithm with molecular dynamics and adaptive boundaries approach. Even though previous works proved usefulness of the Wang tiling for material reconstruction, still plenty of questions remain unanswered. In here we would like to provide simulations with emphasis on the overall particle distribution and the ratio of hard disc number to tile size. The results and discussion should followers help with settings of both tile generations and the tiling algorithms when creating samples of various degree of heterogeneity.

  19. [The anatomical concept of Ma Wang Dui archeological artifacts].

    Science.gov (United States)

    Yang, Su-Tso

    2010-01-01

    Amongst the archeological findings of Ma Wang Dui that concern the human anatomy, the first noted was a well-preserved female corpse, which demonstrated superb antiseptic techniques of the ancient Chinese. Also, 14 medical books were excavated and revealed a prototype of human visceral anatomy. The differentiation between small and large intestines was absent, and only the term of "intestine" was mentioned. The term of "triple energizers" was absent, too. However, contexts of surface anatomy were already abundant. Analyzing the terms of relative position, the anatomical position portrayed by the Ma Wang Dui medical texts is very similar to that of modern medicine.

  20. The Qing and Russia in Central Asia : A Comparative Study of Motives for Political Expansion

    OpenAIRE

    Løvold, Thomas Ohren

    2009-01-01

    The Peoples Republic of China’s Xinjiang-Uygur Autonomous Region, or eastern Central Asia, is an area that has recently seen large scale ethnic unrest, as the native Uygurs have protested violently against Chinese domination in the region. This thesis is a discussion of the background for why Xinjiang today is under Chinese rule. To and a half centuries ago, in 1755-59, the Manchu Qing dynasty (1636-1911) conquered Xinjiang and incorporated it into their state, and this conquest contributed s...

  1. "To Feel at Home in the Wonderful World of Modern Science": New Chinese Historiography and Qing Intellectual History.

    Science.gov (United States)

    Sela, Ori

    2017-09-01

    Argument In recent decades a large body of scholarship on the first half of twentieth-century China has successfully shown the ways in which history and historiography had been constructed at the time, as well as the links between history, national identity, education, and politics that was forged during this period. In this paper, I examine Qing intellectual history, in particular that of the mid or "High Qing." I discuss the development of the historiography of this field in the early twentieth century by drawing on the larger developments in historiography; by demonstrating how these developments had shaped Qing intellectual history for later times; by focusing on the historical actors' sense of the importance of "science," being "scientific," and "modernization"; and, by unraveling the intimate connections to older historiographical narratives going back all the way to the eighteenth and nineteenth centuries.

  2. Browse Author Index

    African Journals Online (AJOL)

    Wang, Mao-shan · Wang, Meng · Wang, Ming-Rui · Wang, MQ · Wang, P · Wang, Q · Wang, Qing-cai · Wang, Qing-Hua · Wang, Qinqin · Wang, R · Wang, Rui · Wang, S · Wang, Sha-Sha · Wang, Shijun · Wang, SJ · Wang, Su-Juan · Wang, W · Wang, Wei 4351 - 4400 of 4947 Items >>.

  3. [Contention on the theory of processing techniques of Chinese materia medica in the Ming-Qing period].

    Science.gov (United States)

    Chen, Bin; Jia, Tianzhu

    2015-03-01

    On the basis of the golden stage of development of processing techniques of medicinals in the Song dynasty, the theory and techniques of processing in the Ming-Qing dynasties developed and accomplished further. The knowledge of some physicians on the processing of common medicinal, such as Radix rehmannia and Radixophiopogonis, was questioned, with new idea of processing methods put forward and argued against those insisting traditional ones, marking the progress of the art of processing. By reviewing the contention of technical theory of medicinal processing in the Ming-Qing period, useful references can be provided for the inheritance and development of the traditional art of processing medicinals.

  4. Factors associated with utilization of reproductive healthcare services among migrant women workers in Chong Qing, China.

    Science.gov (United States)

    Su, Shu; Zhang, Fan; Liu, Qin; Wang, Yang; Wen, Jing; Tang, Xiaojun; Zhang, Lei

    2014-10-01

    To investigate the use of reproductive healthcare services among migrant women workers in Chong Qing, China, and provide suggestions to improve the utilization of these services by young women. In a qualitative interview-based study between March, 2013 and June, 2013, personal in-depth interviews were conducted among young women workers, factory doctors, healthcare service providers, and policy-makers in Chong Qing, China. Women workers seldom visited hospitals and did so only when their pain became unbearable. The workers' use of reproductive healthcare services was particularly influenced by the high cost of hospitalization and long waiting periods. Factory doctors could only solve minor problems. Public healthcare providers stated that migrant women had a higher morbidity rate from reproductive tract infections as compared with local women. The policy-makers considered that the health system was beneficial to women's reproductive health; however, few workers had good comprehension of government policies. Migrant women workers are vulnerable owing to lack of reproductive health care. The government and both social and health enterprise should consider the convenience of these women and the affordability of treatments when formulating reproductive healthcare policies. Effective measures should be taken to improve the use of these services by migrant women workers. Copyright © 2014 International Federation of Gynecology and Obstetrics. Published by Elsevier Ireland Ltd. All rights reserved.

  5. The Characters of Leap Years in Qing Calendars (1644-1911)

    Science.gov (United States)

    Lu, Dalong

    In Qing Dynasty (1644-1911) three different calendars had been put into use which titles are Xiyang Xinfa Lishu (Treatise on Astronomy and Calendrical Science according to the New Method in West 1645-1666) Yuzhi Lixiang Kaocheng (Compendium of Calendrical Science and Astronomy compiled by Imperial Order 1725-1742) and Yuzhi Lixiang Kaocheng Houbian (Sequel Compendium of Calendrical Science and Astronomy compiled by Imperial Order 1742-1911). The characters of leap years in the three calendars are different for the last one which is selected the year of 1723 as it epoch and named as Guimao Yuan Li. This calendar is based on the 33-year pattern of leap years (there is a rather exact accord between days and years over this interval with eight days being intercalated per 33 years) and is slightly different from the former two calendars. Therefore the calendars of Qing Dynasty complied by Western Jesuits and Chinese astronomers can be regarded as the remarkable achievements in the history of calendar in the world.

  6. [Study of Paints and Drawing Techniques of Fine Brushwork Yunlong Ripples Painting in Qing Dynasty].

    Science.gov (United States)

    Hao, Sheng-cai; Shi, Ji-long; Wang, Ji-gang; He, Qiu-ju; Qi, Xiao-kun; Zhou, Zhong; Zhou, Wen-hua

    2016-02-01

    In order to study the paints and techniques of decorative patterns of dragon among clouds and water waves, the materials based on a Qing Dynasty meticulous painting were measured by three-dimensional video microscopy, Raman microscopy and energy dispersive X-ray fluorescence spectroscopy. The results showed that the green clothes was firstly colored by Paris green, the decorative patterns of dragon among clouds and water waves were then painted by hematite, the edge was delineated by brass powder at last. The dark yellow area within the decorative patterns was presented due to the interaction of green and red paints. In addition, ultramarine blue was checked in the painting. According to the first synthesized time of ultramarine blue and Paris green, we can make sure the time limit of the painting finished.

  7. Between the Living and the Dead: Trauma Medicine and Forensic Medicine in the Mid-Qing.

    Science.gov (United States)

    Wu, Yi-Li

    2015-03-01

    This paper analyzes the influence of forensic medicine on therapeutic medicine through a case study of Qian Xiuchang and Hu Tingguang, two Chinese doctors who specialized in treating traumatic injuries. During the early nineteenth century, both men compiled medical treatises that sought to improve on a scholarly model of "rectifying bones" articulated in 1742 by the Imperially-Compiled Golden Mirror of the Medical Lineage. Both texts also incorporated information from forensic medicine, including official inquest diagrams and checklists promulgated by the Qing government. I show that they drew on these forensic materials to help address two interlinked medical issues: understanding the effects of injury on different parts of the body, and clarifying the location and form of the body's bones. Overall, I suggest that the exchange of ideas between the realm of therapeutic medicine and forensic medicine was an important epistemological strategy that doctors and officials alike employed to improve their knowledge of the material body.

  8. Protective effect of a Chinese Medicine formula He-Ying-Qing-Re Formula on diabetic retinopathy.

    Science.gov (United States)

    Wang, Leilei; Wang, Ning; Tan, Hor-yue; Zhang, Yinjian; Feng, Yibin

    2015-07-01

    He-Ying-Qing-Re Formula (HF) is a formula modified from "Si-Miao-Yong-An Decoction", a traditional Chinese medical classic emerged in the Qing dynasty and has been reported for treatment of vascular diseases. HF, containing 8 herbs, has been used in local hospital for decades as a complementary method for diabetic retinopathy (DR) with retinal vascular dysfunction. Clinical reports revealed HF could ameliorate vision defects, microaneurysms, hemorrhages and macular edema. The aim of this study is to investigate the anti-DR action of HF and its underlying mechanism experimentally. Chromatographic fingerprinting of HF and rodent model of DR were established; hypoglycemic effect of HF was measured by fasting, random blood glucose and glucose tolerance test; vascular degeneration was measured by retinal digestion; blood-retina-barrier (BRB) permeability was assessed with Evans Blue leakage assay. Advanced glycation end products (AGEs) were measured in vitro and in vivo level; Migration of retinal vascular endothelial cells were determined by wound healing and transwell chamber assays; permeability of endothelial monolayer was monitored with dextran transport. AGEs-related proteins and signaling were measured with immunoblotting and immunohistochemistry. Chlorogenic acid, ferulic acid and arctin were identified as major components in HF; HF suppresses retinal vasculature degeneration and BRB permeability damage without significant inhibition on hyperglycemia; HF reduces in vitro and in vivo formation of AGEs and AGEs-induced migration as well as permeability of retinal vascular endothelial cells. Expression of tight junction proteins Zo-1 and Claudin-1 was increased while activation of AGEs receptor and downstream signaling Akt were suppressed upon HF treatment. HF exhibits protective effect against diabetic retinopathy, which may be associated with inhibition on AGEs and recovery on endothelial dysfunction via modulation of tight junction and AGEs downstream signaling

  9. Control of accuracy in the Wang-Landau algorithm

    Science.gov (United States)

    Barash, L. Yu.; Fadeeva, M. A.; Shchur, L. N.

    2017-10-01

    The Wang-Landau (WL) algorithm has been widely used for simulations in many areas of physics. Our analysis of the WL algorithm explains its properties and shows that the difference of the largest eigenvalue of the transition matrix in the energy space from unity can be used to control the accuracy of estimating the density of states. Analytic expressions for the matrix elements are given in the case of the one-dimensional Ising model. The proposed method is further confirmed by numerical results for the one-dimensional and two-dimensional Ising models and also the two-dimensional Potts model.

  10. THE APPLICATION OF SURVEY IN ER WANG TEMPLE RESTITUTING

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    W. Shuai

    2013-07-01

    Full Text Available Er Wang Temple, in World Heritage Site "Dujiang Weirs and Qingchengshan Mountai", was severely destroyed in Wenchuan earthquake of May 2008. There are several problems at different level in every building, such as structural distortion, foundation displacement, wall fracture, roof damage, etc. The stage was completely collapsed in the earthquake. Tableland the stage situated had a huge crack and slope collapse. This article is for the stage renovation. The survey of damage in earthquake is the basis of Er Wang Temple restituting. Survey including field survey after the earthquake and the measurement and investigation for the remained construction member of the main wood structure. For field survey, the basis of pillars which had not have significantly affects in earthquake could be seem as the reference points for measurement. The investigation of remained main wood construction member, especially the size of the key structures and site and manufacture method of the joints, is the important basis for recovery stage. Our team did our utmost to restore the original appearance of stage in design, materials and craft by various tools, which include measured drawings in different times, old images collection, fine measuring by 3D laser scan, measurement of leftover pieces, logical inference.

  11. Introduction: Paving the Old-New Way from Qing to China.

    Science.gov (United States)

    Sela, Ori

    2017-09-01

    The funeral procession of Sheng Xuanhuai (, 1844-1916) - the renowned Qing scholar-official, financier, and "father of Chinese industrialism" - meandered through the streets of Shanghai on 18 November 1917. The funeral was a grand event, one that was purportedly documented in film, later to be distributed as the first "news short-film" () in China. The North China Herald reported on the event in some detail, at times in rather florid language, and suggested that "the cortege was splendid and impressive, bringing back the days of the Manchu emperors. The ceremonial costumes, the musical instruments and much more of the accoutrements dated back to the days of the Empire" ("Sheng Kung-pao's Funeral," 1917, 467-68). And indeed, the procession included a variety of ritual customs and insignia from Qing (1644-1911) times: imperial banners, ancestral tablets, Buddhist and Daoist priests, paper artifacts, and much more. Simultaneously, nonetheless, other kinds of participants and objects - new and not of imperial pedigree - were part of and intermixed with the older materials: certificates of rank were carried on cars; boy scouts and college students marched alongside the priests; many of the participants arrived by train (mainly from Sheng's hometown, Suzhou); and as the Shanghai portion of the procession ended, it continued by steamer to Suzhou. The conclusion of the North China Herald account, however, seems to have emphasized a dichotomy of old and new rather than a joyful mix of the two: Hundreds of men, dressed in the ancient costume of the old dynasties, bore a strong contrast to the eight behind them, sons of intimate friends of the deceased. They were on horseback and wore high silk hats, frock coats and white breeches tucked in riding boots. Truly the passing of the old and the entering of the new. (Ibid.; emphasis added) This view - the old giving way to the new - was not just an off-hand (Western) journalistic analysis; it was part of a larger discourse about

  12. Ke Wang, a Chinese television soap opera with a message.

    Science.gov (United States)

    Wang, M; Singhal, A

    1992-01-01

    The Chinese soap opera, Ke Wang, was created by Li Xiaoming between August 1989 and June 1990 and produced at a cost of US$4650 per episode. The characters were drawn from everyday ordinary Chinese life: a traditional and open-minded and caring woman, a typical mother who works hard and loves her children, a highly educated upwardly mobile man who divorces his wife, a professor criticized during the Cultural Revolution, a doctor prejudiced against ordinary people, a kind honest man who marries the divorcee, a friend of the divorcee, a man who is optimistic in spite of bad experiences during the Cultural Revolution, and an excellent medical doctor who also resolves conflicts. The program was very popular, even among Communists, because of its value-based content, the real-life nature of the show, the change from highly restricted programming, the elaborate and supportive media coverage, and dialogue which closely matches audience preferences. The show has been aired by over 100 stations to date and has reached a total estimated audience of 550 million. The sale of television sets has increased since the show's appearance. The script reflects the conflicts between traditional and modern Chinese values. Pro-social values and behaviors are learned from the role models depicted; examples are given of immediate social impact. Ke Wang was a by-product of the Beijing Television Arts Center's interest in designing television programs that are relevant to the lives of ordinary people. The 60-minute scripts dealt with issues such as the status of women, social morality, family harmony, class conflict, responsible parenthood, maintenance of traditional culture, volunteerism, child development, and coping with physical disability. The Chinese government hailed Ke Wang as model television and awarded US$20,000 in prize money to the producers. The Chinese government is planning to produce other entertainment-education soap operas, which raises the problem of blatant, political

  13. Passion, Romance, and Qing: The World of Emotions and States of Mind in Peony Pavilion (3 vols.)

    OpenAIRE

    Tan, Tian Yuan; Santangelo, Paolo

    2014-01-01

    Passion, Love, and Qing examines the vitality of Peony Pavilion, the most famous drama in Ming China (1368-1644), through four essays (by Isabella Falaschi, Paolo Santangelo,\\ud Tian Yuan Tan, and Rossella Ferrari) and an extensive Glossary of specific terms and expressions related to the representation of emotions and states of mind. It explores\\ud the evolution and permanence of the universal message about passion or emotions contained in the language of the play. Written in the late Ming, ...

  14. Multiple Walkers in the Wang-Landau Algorithm

    Energy Technology Data Exchange (ETDEWEB)

    Brown, G

    2005-12-28

    The mean cost for converging an estimated density of states using the Wang-Landau algorithm is measured for the Ising and Heisenberg models. The cost increases in a power-law fashion with the number of spins, with an exponent near 3 for one-dimensional models, and closer to 2.4 for two-dimensional models. The effect of multiple, simultaneous walkers on the cost is also measured. For the one-dimensional Ising model the cost can increase with the number of walkers for large systems. For both the Ising and Heisenberg models in two-dimensions, no adverse impact on the cost is observed. Thus multiple walkers is a strategy that should scale well in a parallel computing environment for many models of magnetic materials.

  15. Epidemics in Ming and Qing China: Impacts of changes of climate and economic well-being.

    Science.gov (United States)

    Pei, Qing; Zhang, David D; Li, Guodong; Winterhalder, Bruce; Lee, Harry F

    2015-07-01

    We investigated the mechanism of epidemics with the impacts of climate change and socio-economic fluctuations in the Ming and Qing Dynasties in China (AD 1368-1901). Using long-term and high-quality datasets, this study is the first quantitative research that verifies the 'climate change → economy → epidemics' mechanism in historical China by statistical methods that include correlation analysis, Granger causality analysis, ARX, and Poisson-ARX modeling. The analysis provides the evidences that climate change could only fundamentally lead to the epidemics spread and occurrence, but the depressed economic well-being is the direct trigger of epidemics spread and occurrence at the national and long term scale in historical China. Moreover, statistical modeling shows that economic well-being is more important than population pressure in the mechanism of epidemics. However, population pressure remains a key element in determining the social vulnerability of the epidemics occurrence under climate change. Notably, the findings not only support adaptation theories but also enhance our confidence to address climatic shocks if economic buffering capacity can be promoted steadily. The findings can be a basis for scientists and policymakers in addressing global and regional environmental changes. Copyright © 2015 Elsevier Ltd. All rights reserved.

  16. The Wang-Meng interacting model and the gravitational collapse

    Energy Technology Data Exchange (ETDEWEB)

    Campos, Miguel de [Universidade Federal de Roraima, Boa Vista (Brazil)

    2013-07-01

    Full text: Several alternatives have appear in the literature to supply the accelerated process of universal expansion, and the simplest possibility is to consider the inclusion of a cosmological constant. The inclusion can be realized in both sides of the Einstein field equations, furnishing different physical interpretations in accord with the side of the Einstein field equations where the Λ is added. Considering the inclusion of the cosmological constant in the energy momentum tensor, this additional content is generally interpreted as the energy storage on the vacuum state of all fields in the universe. The inclusion of a vacuum component in the universal fluid furnishes an excellent description of the observed universe, but from the theoretical point of view we do not understand why the vacuum energy is so small and of the same order of magnitude of the matter density (cosmological constant problem). Depending on the point of view of the cosmological constant problem, competing approaches were developed considering a dynamical cosmological 'constant'. A more richer possibility is to consider a non-gravitational interaction models, where the interaction can occur between the dark components, the ordinary matter, and they do not evolve separately. The coupling between dark matter and dark energy has been considered in the literature in a three different ways: dark matter decaying to dark energy; dark energy decaying to dark matter; interacting in both directions. Wang and Meng (CQG 22, 283,2005) considered an alternative to the usual approach for the decay law of the Λ-term assuming the effect of the vacuum in the matter expansion rate. The simple manner adopt by the authors unified several current models that includes a vacuum decaying component interacting with matter content. The vacuum component alters the dynamics of the universal expansion process, then is a natural question: how is the influence of the vacuum energy in the gravitational

  17. Two New Monoterpene Glycosides from Qing Shan Lu Shui Tea with Inhibitory Effects on Leukocyte-Type 12-Lipoxygenase Activity

    Directory of Open Access Journals (Sweden)

    Ding Zhi Fang

    2013-04-01

    Full Text Available We evaluated the inhibitory effect of 12 Chinese teas on leukocyte-type 12-lipoxygenase (LOX activity. Tea catechins such as epigallocatechin gallate have been known to exhibit leukocyte-type 12-LOX inhibition. Qing Shan Lu Shui, which contains lower catechin levels than the other tested teas, suppressed leukocyte-type 12-LOX activity. To characterize the bioactive components of Qing Shan Lu Shui, leukocyte-type 12-LOX inhibitory activity–guided fractionation of the aqueous ethanol extract of the tea was performed, resulting in the isolation of two new monoterpene glycosides: liguroside A (1 and B (2. The structures of compounds 1 and 2 were characterized as (2E,5E-7-hydroperoxy-3,7-dimethyl-2,5-octadienyl-O-(α-L-rhamnopyranosyl-(1″→3′-(4′″-O-trans-p-coumaroyl-β-D-glucopyranoside and (2E,5E-7-hydroperoxy-3,7-dimethyl-2,5-octa-dienyl- O-(α-L-rhamnopyranosyl-(1″→3′-(4′″-O-cis-p-coumaroyl-β-D-glucopyranoside, respectively, based on spectral and chemical evidence. Ligurosides A (1 and B (2 showed inhibitory effects on leukocyte-type 12-LOX activity, with IC50 values of 1.7 and 0.7 μM, respectively.

  18. The ABCs of Chinese Pop: Wang Leehom and the Marketing of a Global Chinese Celebrity

    OpenAIRE

    Grace Wang

    2012-01-01

    How did singer Wang Leehom, a Chinese American raised in the suburbs of New York, end up becoming one of the industry heavyweights of Mandopop (Mandarin-language pop music)? This essay uses Wang as a case study to investigate how discourses of race, market, and belonging are reworked in global contexts. Drawing on Sau-ling Wong’s theoretical insights on transnational processes of race, citizenship, and belonging, it argues that Wang capitalizes on a fluid dynamic of sameness and difference to...

  19. Yue Joseph Wang named Grant A. Dove Professor of Electrical and Computer Engineering

    OpenAIRE

    Owczarski, Mark

    2009-01-01

    Yue Joseph Wang, professor of electrical and computer engineering in the College of Engineering at Virginia Tech, has been named the Grant A. Dove Professor of Electrical and Computer Engineering by the Virginia Tech Board of Visitors.

  20. Cryptanalysis of Wang et al.’s lattice-based key exchange protocol

    Directory of Open Access Journals (Sweden)

    Daya Sagar Gupta

    2016-09-01

    Full Text Available Wang et al. proposed a new hard problem on lattices which is an extension of the small integer solution (SIS on lattices. This new generated hard problem is named to be bilateral in-homogeneous small integer solution (Bi-ISIS. Using the hardness of Bi-ISIS, Wang et al. proposed a new key exchange protocol, which is based on the lattice-based cryptography. In this paper, we signalize that Wang et al.’s lattice-based key exchange protocol is vulnerable to an attack, namely, man-in-the-middle (MITM attack. Through this attack, Eavesdropper can intercept the authenticated messages and communicate the unauthentic messages among the communicating parties.

  1. [Wang Yinglin and his answer to the questions of a Korean physician].

    Science.gov (United States)

    Liang, Y

    2000-04-01

    The book named Da Chaoxianyi Wen (Answer to the Questions of a Korean Physician), written in 1624, recorded the written answers of Wang Yinglin, a Chinese official in the Ming dynasty, to the questions of Yin Zhiwei, a Korean official physician. The 24 A&Qs concerned about the therapy of ordinary diseases, channels and the theories of TCM, etc. The study of this book could not only clarify various questions on the exchanges between Wang and Yin, but also learn more information on the development of Korean medicine at that time.

  2. The effects of Jiao-Tai-Wan on sleep, inflammation and insulin resistance in obesity-resistant rats with chronic partial sleep deprivation.

    Science.gov (United States)

    Zou, Xin; Huang, Wenya; Lu, Fuer; Fang, Ke; Wang, Dingkun; Zhao, Shuyong; Jia, Jiming; Xu, Lijun; Wang, Kaifu; Wang, Nan; Dong, Hui

    2017-03-23

    Jiao-Tai-Wan (JTW), composed of Rhizome Coptidis and Cortex Cinnamomi, is a classical traditional Chinese prescription for treating insomnia. Several in vivo studies have concluded that JTW could exert its therapeutical effect in insomnia rats. However, the specific mechanism is still unclear. The present study aimed to explore the effect of JTW on sleep in obesity-resistant (OR) rats with chronic partial sleep deprivation (PSD) and to clarify its possible mechanism. JTW was prepared and the main components contained in the granules were identified by 3D-High Performance Liquid Chromatography (3D-HPLC) assay. The Male Sprague-Dawley (SD) rats underwent 4 h PSD by environmental noise and the treatment with low and high doses of JTW orally for 4 weeks, respectively. Then sleep structure was analyzed by electroencephalographic (EEG). Inflammation markers including high-sensitivity C reactive protein (hs-CRP), tumor necrosis factor-α (TNF-α) and interleukin-6 (IL-6) levels were examined in the rat plasma. Meanwhile, metabolic parameters as body weight increase rate, fasting plasma glucose (FPG), fasting insulin (FINS) levels and insulin resistance index (HOMA-IR) were measured. The expressions of clock gene cryptochromes (Cry1 and Cry2) and inflammation gene nuclear factor-κB (NF-κB) in peripheral blood monocyte cells (PBMC) were also determined. The result showed that the administration of JTW significantly increased total sleep time and total slow wave sleep (SWS) time in OR rats with PSD. Furthermore, the treatment with JTW reversed the increase in the markers of systemic inflammation and insulin resistance caused by sleep loss. These changes were also associated with the up-regulation of Cry1 mRNA and Cry 2 mRNA and the down-regulation of NF-κB mRNA expression in PBMC. This study suggests that JTW has the beneficial effects of improving sleep, inflammation and insulin sensitivity. The mechanism appears to be related to the modulation of circadian clock and

  3. A Primary Study on the Recording Method of Interior Decoration in Qing Dynasty – A Case Study of Interior Decoration of Jingfu Palace

    Directory of Open Access Journals (Sweden)

    X. Rong

    2017-08-01

    Full Text Available The existing interior decoration of Qing Dynasty is the master of that of each dynasty, with its diversified forms and complicated functions. As early as 1920s, the Rehabilitation Committee of Qing court recorded the interior furnishing in the Forbidden City by using Chinese traditional documentary method. Today, along with the constantly updated techniques, the recording method for the current situation of interior decoration has gradually developed from two-dimensional drawings into digital and comprehensive record. However, the current research results are mostly limited to a single field. This paper takes the digital record and reproduction about the current situation of interior decoration in Jingfu Palace in the Forbidden City as an example. Through the use of photogrammetry, 3D laser scanning, virtual display and other technology and equipment at the forefront of architectural field, it makes qualitative and quantitative record about the interior decoration inside Jingfu Palace. By combing with the interpretation of historical documents, it restores the original design ideas hidden behind the current situation of interior decoration, so as to summarize the best recording and reproducing method of interior decoration of Qing Dynasty.

  4. The Tangdan Copper Mines and the 1733 Earthquake: A Mining Community before the Boom in the Far Southwest of Qing China

    Directory of Open Access Journals (Sweden)

    Nanny Kim

    2014-12-01

    Full Text Available In the official records, copper mines in the southwest of the Qing empire seem to suddenly appear in the late 1730s. In part, this impression is an effect of government attention. Copper, which was the most important metal for casting cash coins, became a pressing concern when imports of Japanese copper dwindled. The government responded by developing domestic resources. Seemingly overnight, Yunnan mines reached impressive levels of productivity and replaced imports. For several decades, the Tangdan mines in northeastern Yunnan supplied most of the copper consumed by the centrally important metropolitan mints. The sudden boom is remarkable and not entirely plausible. This article reassesses the history of Qing-period mining by examining a particular case study. It explores an essay about the Dongchuan earthquake of 1733 that provides a glimpse at the empire’s leading copper mines on the eve of the recorded boom. A close analysis of figures, mining technology, and organizational structures reveals that the mines had been developed by mining entrepreneurs and migrant workers for a considerable period of time outside government attention, operating in a gray zone of unlicensed exploitation. The studied case permits a new assessment of the role of the state and of nonstate players in the industry. Moreover, it throws a new light on the image of Qing society and economy created by the official emphasis on agriculture and the actual role of the nonagrarian sector.

  5. A Primary Study on the Recording Method of Interior Decoration in Qing Dynasty - A Case Study of Interior Decoration of Jingfu Palace

    Science.gov (United States)

    Rong, X.; He, B.; Zhuang, L.

    2017-08-01

    The existing interior decoration of Qing Dynasty is the master of that of each dynasty, with its diversified forms and complicated functions. As early as 1920s, the Rehabilitation Committee of Qing court recorded the interior furnishing in the Forbidden City by using Chinese traditional documentary method. Today, along with the constantly updated techniques, the recording method for the current situation of interior decoration has gradually developed from two-dimensional drawings into digital and comprehensive record. However, the current research results are mostly limited to a single field. This paper takes the digital record and reproduction about the current situation of interior decoration in Jingfu Palace in the Forbidden City as an example. Through the use of photogrammetry, 3D laser scanning, virtual display and other technology and equipment at the forefront of architectural field, it makes qualitative and quantitative record about the interior decoration inside Jingfu Palace. By combing with the interpretation of historical documents, it restores the original design ideas hidden behind the current situation of interior decoration, so as to summarize the best recording and reproducing method of interior decoration of Qing Dynasty.

  6. Wang et al., Afr J Tradit Complement Altern Med. (2016) 13(1):134 ...

    African Journals Online (AJOL)

    PROF ADEWUNMI

    GB30) in patients with sciatica, and specific changes in the brain default network (Li et al., 2012). Wang et al. observed the effect of acupuncture Taichong(LR3) and Hegu(LI4) for mild cognitive impairment. (MCI) and Alzheimer diseases (AD), and ...

  7. New Wang-Landau approach to obtain phase diagrams for multicomponent alloys

    Science.gov (United States)

    Takeuchi, Kazuhito; Tanaka, Ryohei; Yuge, Koretaka

    2017-10-01

    We develop an approach to apply the Wang-Landau algorithm to multicomponent alloys in a semi-grand-canonical ensemble. Although the Wang-Landau algorithm has great advantages over conventional sampling methods, there are few applications to alloys. This is because calculating compositions in a semi-grand-canonical ensemble via the Wang-Landau algorithm requires a multidimensional density of states in terms of total energy and compositions, and constructing it is difficult from the viewpoints of both implementation and computational cost. In this study, we develop a simple approach to calculate the alloy phase diagram based on the Wang-Landau algorithm, and show that a number of one-dimensional densities of states could lead to compositions in a semi-grand-canonical ensemble as a multidimensional density of states could. Finally, we apply the present method to Cu-Au and Pd-Rh alloys and confirm that the present method successfully describes the phase diagram with high efficiency, validity, and accuracy.

  8. Evolution of Water Management in Shanxi and Shaanxi Provinces since the Ming and Qing Dynasties of China

    Directory of Open Access Journals (Sweden)

    Mark Yaolin Wang

    2013-06-01

    Full Text Available This article examines some of the forms of water management in Shanxi [山西] and Shaanxi [陕西] provinces during the Ming and Qing dynasties. Facing serious water shortages and shrinking state power for water management, the local society in Shanxi and Shaanxi took over water management and gradually formed a local self-government system for the water resources. Depending on water management organizations in which the local gentry were the core power, the water rules were based on natural topographic conditions, historical water practices in the locality, traditional moral-ethical ideas, and even water policies and water laws. This water management system played a positive role in mobilizing the participation of members, preventing opportunistic behavior such as free riding and rent seeking, while decreasing the probability of water conflicts and the costs of litigation. However, this water management system was also subject to endemic corruption because of the lack of effective monitoring from the local government. As similar problems appear to exist in China today, this article analyzes the features of this water management system, and examines the problems that faced those systems so as to provide a warning from history for modern society.

  9. Retraction Statement: 'MicroRNA-218 increases cellular sensitivity to Rapamycin via targeting Rictor in cervical cancer' by Li J, Wang J, Wang Y, Qiu H.

    Science.gov (United States)

    2017-02-01

    The above article from APMIS, published online on 24 April 2015 in Wiley Online Library (wileyonlinelibrary.com) and in Volume 123, pp. 562-570, has been retracted by agreement between the authors, the journal Editors in Chief, Professors Bodil Norrild, Ben Vainer and Elisabeth Ralfkiaer, and John Wiley & Sons Ltd. The article has been retracted due to errors in the reported results. In this study, the authors used HeLa and SiHa cell lines to investigate the biological roles of miR-218. However, subsequently it emerged that the two cell lines were contaminated in the laboratory by other unknown cell lines. When repeating the experiments, it was found that the functions of miR-218 were not as significant as had been previously reported, especially its effects on rapamycin sensitivity. Reference Li J, Li X, Wang J, Wang Y, Qiu H. MicroRNA-218 increases cellular sensitivity to Rapamycin via targeting Rictor in cervical cancer. APMIS 2015; 123:562-570. doi: 10.1111/apm.12387. © 2016 APMIS. Published by John Wiley & Sons Ltd.

  10. VizieR Online Data Catalog: Kepler multiple transiting planet systems (Wang+, 2015)

    Science.gov (United States)

    Wang, J.; Fischer, D. A.; Xie, J.-W.; Ciardi, D. R.

    2017-10-01

    The sample of MTPSs remains the same as that in Wang et al. (2014, J/ApJ/783/4). From the NASA Exoplanet Archive (http://exoplanetarchive.ipac.caltech.edu), we select Kepler objects of interest (KOIs) that satisfy the following criteria: (1) disposition of either Candidate or Confirmed; (2) with at least two planet candidates; (3) Kepler magnitude (KP) brighter than 13.5. The above selection criteria resulted in 138 MTPSs in Wang et al. (2014, J/ApJ/783/4). With the updated Exoplanet Archive, the selection criteria resulted in 208 MTPSs. In this paper, we focus on the 138 MTPSs to be consistent with previous work. (4 data files).

  11. Becoming an International Scientist in South Korea: Ho Wang Lee's Research Activity about Epidemic Hemorrhagic Fever.

    Science.gov (United States)

    Shin, Miyoung

    2017-04-01

    In the 1960-70s, South Korea was still in the position of a science latecomer. Although the scientific research environment in South Korea at that time was insufficient, there was a scientist who achieved outcomes that could be recognized internationally while acting in South Korea. He was Ho Wang Lee(1928~ ) who found Hantann Virus that causes epidemic hemorrhagic fever for the first time in the world. It became a clue to identify causative viruses of hemorrhagic diseases that were scattered here and there throughout the world. In addition, these outcomes put Ho Wang Lee on the global center of research into epidemic hemorrhagic fever. This paper examines how a Korean scientist who was in the periphery of virology could go into the central area of virology. Also this article shows the process through which the virus found by Ho Wang Lee was registered with the international academia and he proceeded with follow-up research based on this progress to reach the level at which he generalized epidemic hemorrhagic fever related studies throughout the world. While he was conducting the studies, experimental methods that he had never experienced encountered him as new difficulties. He tried to solve the new difficulties faced in his changed status through devices of cooperation and connection. Ho Wang Lee's growth as a researcher can be seen as well as a view of a researcher that grew from a regional level to an international level and could advance from the area of non-mainstream into the mainstream. This analytic tool is meaningful in that it can be another method of examining the growth process of scientists in South Korea or developing countries.

  12. Morphology and geochemistry of placer gold from Wang River, Lampang Province, Northern Thailand

    Science.gov (United States)

    Lim, D.; Lee, I.

    2011-12-01

    Wang River (Mae Nam Wang) in Lampang Province, Northern Thailand which is surrounded with many lode gold deposits has potential to develop as a placer gold deposit. Gold particles from 10 sites in Wang River range from fine to coarse (electrum or high purity gold with high fineness (1000Au/Au+Ag) levels up to 951 as well as a minor amount of Cu and Hg. Normally, the zoning patterns of Au and Ag are common in placer gold and the high fineness in rim can be explained by either selective extraction of Ag or precipitation of Au. However, there is no significant difference in fineness between core and rim in gold grains in this study even though there are differences in composition among grains. Many cavities are also shown filling with silicate and/or clay mineral in microtextures. These geochemical signatures from microtextures are capable of providing genetic implication. Furthermore, the combination of results such as shape parameter, geochemical signature, and assemblages of heavy minerals can be a useful tool in exploration for gold.

  13. The ABCs of Chinese Pop: Wang Leehom and the Marketing of a Global Chinese Celebrity

    Directory of Open Access Journals (Sweden)

    Grace Wang

    2012-06-01

    Full Text Available How did singer Wang Leehom, a Chinese American raised in the suburbs of New York, end up becoming one of the industry heavyweights of Mandopop (Mandarin-language pop music? This essay uses Wang as a case study to investigate how discourses of race, market, and belonging are reworked in global contexts. Drawing on Sau-ling Wong’s theoretical insights on transnational processes of race, citizenship, and belonging, it argues that Wang capitalizes on a fluid dynamic of sameness and difference to appeal to a heterogeneous Chinese-speaking audience that stretches across China to Taiwan, Hong Kong, Southeast Asia, and the greater Chinese diaspora. Through an examination of the racial and national contexts that frame Wang’s participation in Mandopop, this essay analyzes the particular calibrations of Chineseness that emerge from the singer’s music and public image and the imperfect translation of identities such as Chinese American, Chinese diasporic, and Chinese across diverse linguistic and national communities.

  14. Security analysis of boolean algebra based on Zhang-Wang digital signature scheme

    Science.gov (United States)

    Zheng, Jinbin

    2014-10-01

    In 2005, Zhang and Wang proposed an improvement signature scheme without using one-way hash function and message redundancy. In this paper, we show that this scheme exits potential safety concerns through the analysis of boolean algebra, such as bitwise exclusive-or, and point out that mapping is not one to one between assembly instructions and machine code actually by means of the analysis of the result of the assembly program segment, and which possibly causes safety problems unknown to the software.

  15. Conodont index fossil Hindeodus changxingensis Wang fingers greatest mass extinction event

    Science.gov (United States)

    Metcalfe, I.; Nicoll, R.S.; Wardlaw, B.R.

    2007-01-01

    The marine conodont fossil species, Hindeodus changxingensis Wang, that has a distinctive morphology, is restricted to a very narrow stratigraphic interval essentially from the Permian-Triassic extinction event through the internationally recognized boundary and into the very earliest Triassic. The species is geographically widespread in the Tethyan Region, from Italy to South China, and serves as a characteristic index fossil to reliably identify this short but critical interval that encompasses the greatest mass extinction of life on earth and the boundary between the Paleozoic and Mesozoic Eras. ?? 2007 Nanjing Institute of Geology and Palaeontology, CAS.

  16. Interview with Xiaoli Wang PhD winner of CACA 2016 Young Investigator Award

    Directory of Open Access Journals (Sweden)

    Xiaoli Wang

    2016-07-01

    Full Text Available Xiaoli Wang is currently an R&D Senior Scientist in Agilent’s HPLC instrument R&D group at Agilent Technologies, Waldbronn, Germany. Prior to this, he was an R&D manager in Agilent’s CrossLab Group in the US focusing on development of novel chromatographic columns. He has a B.S. degree in Chemistry from Peking University, Beijing China and a PhD. degree in Analytical Chemistry from the University of Minnesota in 2006. He started his industrial career in the pharmaceutical industry at AstraZeneca for four years before joining Agilent Technologies in 2010. Recently, he won the prestigious 2016 Young Investigator Award from Chinese American Chromatography Association (CACA. This interview was conducted by Roland J.W. Meesters PhD, Editor-in-Chief of Journal of Applied Bioanalysis.

  17. Entropy of diluted antiferromagnetic Ising models on frustrated lattices using the Wang-Landau method.

    Science.gov (United States)

    Shevchenko, Yuriy; Nefedev, Konstantin; Okabe, Yutaka

    2017-05-01

    We use a Monte Carlo simulation to study the diluted antiferromagnetic Ising model on frustrated lattices including the pyrochlore lattice to show the dilution effects. Using the Wang-Landau algorithm, which directly calculates the energy density of states, we accurately calculate the entropy of the system. We discuss the nonmonotonic dilution concentration dependence of residual entropy for the antiferromagnetic Ising model on the pyrochlore lattice, and compare it to the generalized Pauling approximation proposed by Ke et al. [Phys. Rev. Lett. 99, 137203 (2007)PRLTAO0031-900710.1103/PhysRevLett.99.137203]. We also investigate other frustrated systems, the antiferromagnetic Ising model on the triangular lattice and the kagome lattice, demonstrating the difference in the dilution effects between the system on the pyrochlore lattice and that on other frustrated lattices.

  18. Density of states for systems with multiple order parameters: a constrained Wang-Landau method

    Science.gov (United States)

    Chan, Chor-Hoi; Brown, Gregory; Rikvold, Per Arne

    2017-11-01

    A macroscopically constrained Wang-Landau Monte Carlo method was recently proposed to calculate the joint density of states (DOS) for systems with multiple order parameters. Here we demonstrate results for a nearest-neighbor Ising antiferromagnet with ferromagnetic long-range interactions (a model spin-crossover material). Its two relevant order parameters are the magnetization M and the staggered magnetization M s. The joint DOS, g(E, M, M s) where E is the total system energy, is calculated for zero external field and long-range interaction strength, and then obtained for arbitrary values of these two field-like model parameters by a simple transformation of E. Illustrations are shown for several parameter sets.

  19. The organic materials in the Five Northern Provinces' Assembly Hall: disclosing the painting technique of the Qing dynasty painters in civil buildings

    Science.gov (United States)

    Lluveras-Tenorio, A.; Bonaduce, I.; Sabatini, F.; Degano, I.; Blaensdorf, C.; Pouyet, E.; Cotte, M.; Ma, L.; Colombini, M. P.

    2015-11-01

    The beiwusheng huiguan (`Meeting hall of the Five Northern Dynasties') is a building complex from the Qing dynasty (1636-1912 ad) located in Wafangdian, near Ziyang, in the south of the Chinese Province of Shaanxi. Two of the preserved halls are richly decorated with wall paintings dated probably in 1848 ad and representing scenes of the `Romance of the Three Kingdoms' and Confucian moral tales. They are a rare example of well-preserved mural paintings of high artistic value inside civil buildings. The aims of this paper are the chemical characterization and localization of organic materials used as binders and colorants in the wall paintings. A multi-analytical approach, consisting in the combined use of gas chromatographic-mass spectrometric techniques (GC/MS and Py-GC/MS) and high-pressure liquid chromatography with diode array detector (HPLC-DAD), was chosen for these purposes. Proteinaceous materials (animal glue and egg), saccharide material (fruit tree gum) and a siccative oil were identified in different paint layers supplying invaluable information about the painting technique used. Moreover, the analyses of organic dyes allowed identifying indigo and gallic acid in more than one sample adding fundamental information about Chinese artists' techniques in mural paintings, missing from the previous studies. To shed light on the gilding technique, the distribution of the painting materials was achieved by means of synchrotron radiation Fourier transform infrared spectroscopy (SR micro-FTIR) and X-ray fluorescence (SR micro-XRF). The results obtained from the multi-analytical approach enabled us to determine the organic materials both binders and organic colorants used by Chinese artisans, highlighting the high technical level achieved in nineteenth century. The binding media and the organic colorants identified, as well as their distribution, allowed the discussion on the painting technique used by the artists of the Qing dynasty giving information for the

  20. Multi-GPU-based Swendsen-Wang multi-cluster algorithm with reduced data traffic

    Science.gov (United States)

    Komura, Yukihiro

    2015-10-01

    The computational performance of multi-GPU applications can be degraded by the data communication between each GPU. To realize high-speed computation with multiple GPUs, we should minimize the cost of this data communication. In this paper, I propose a multiple GPU computing method for the Swendsen-Wang (SW) multi-cluster algorithm that reduces the data traffic between each GPU. I realize this reduction in data traffic by adjusting the connection information between each GPU in advance. The code is implemented on the large-scale open science TSUBAME 2.5 supercomputer, and its performance is evaluated using a simulation of the three-dimensional Ising model at the critical temperature. The results show that the data communication between each GPU is reduced by 90%, and the number of communications between each GPU decreases by about half. Using 512 GPUs, the computation time is 0.005 ns per spin update at the critical temperature for a total system size of N =40963.

  1. Somatic embryogenesis and enhanced shoot organogenesis in Metabriggsia ovalifolia W. T. Wang

    Science.gov (United States)

    Ouyang, Yao; Chen, Yulu; Lü, Jinfeng; Teixeira da Silva, Jaime A.; Zhang, Xinhua; Ma, Guohua

    2016-01-01

    An efficient protocol providing a dual regeneration pathway via direct shoot organogenesis and somatic embryogenesis for an endangered species, Metabriggsia ovalifolia W. T. Wang, was established from leaf explants. When applied at 2.5 μM, the cytokinins 6-benzyladenine (BA) or thidiazuron (TDZ) and the auxins indole-3-butyric acid (IBA), α-naphthaleneacetic acid (NAA) and indole-3-acetic acid (IAA) could induce shoots when on basal Murashige and Skoog (MS) medium. BA and TDZ could induce more adventitious shoots (19.1 and 31.2/explant, respectively) than NAA (4.6/explant), IBA (5.7/explant) or IAA (6.4/explant). BA and TDZ at 5–10 μM could induce both shoots and somatic embryos. A higher concentration of TDZ (25 μM) induced only somatic embryos (39.8/explant). The same concentration of BA induced both adventitious shoots (23.6/explant) and somatic embryos (9.7/explant). Thus, somatic embryogenesis in this plant needs a high cytokinin concentration (BA; TDZ), as evidenced by histology. Somatic embryos germinated easily when left on the same media, but formed adventitious roots in two weeks on MS supplemented with 0.5 μM NAA, 0.5 μM IBA and 0.1% activated charcoal. Over 93% of plantlets survived following acclimatization and transfer to a mixture of sand and vermiculite (1:1, v/v) in trays. PMID:27090564

  2. Mid-Late Triassic metamorphic event for Changhai meta-sedimentary rocks from the SE Jiao-Liao-Ji Belt, North China Craton: Evidence from monazite U-Th-Pb and muscovite Ar-Ar dating

    Science.gov (United States)

    Liu, Fulai; Wang, Fang; Liou, J. G.; Meng, En; Liu, Jianhui; Yang, Hong; Xiao, Lingling; Cai, Jia; Shi, Jianrong

    2014-11-01

    The precise constraints on the timing of metamorphism of the Changhai metamorphic complex is of great importance considering the prolonged controversial issue of the north margin and the extension of the Sulu-Dabie HP-UHP Belt. While the monazite U-Th-Pb and muscovite 40Ar/39Ar techniques are widely accepted as two of the most powerful dating tools for revealing the thermal histories of medium-low grade metamorphic rocks and precisely constraining the timing of metamorphism. The Changhai metamorphic complex at the SE Jiao-Liao-Ji Belt, North China Craton consists of a variety of pelitic schist and Grt-Ky-bearing paragneiss, and minor quartzite and marble. Analyses of mineral inclusions and back-scattered electric (BSE) images of monazites, combined with LA-ICP-MS U-Th-Pb ages for monazites and 40Ar/39Ar ages for muscovites, provide evidence of the origin and metamorphic age of the Changhai metamorphic complex. Monazites separates from various Grt-Mus schists and Grt-Ky-St-Mus paragneisses exhibit homogeneous BSE images from cores to rims, and contain inclusion assemblages of Grt + Mus + Qtz ± Ctd ± Ky in schist, and Grt + Ky + St + Mus + Pl + Kfs + Qtz inclusions in paragneiss. These inclusion assemblages are very similar to matrix minerals of host rocks, indicating they are metamorphic rather than inherited or detrital in origin. LA-ICP-MS U-Th-Pb dating reveals that monazites of schist and paragneiss have consistent 206Pb/238U ages ranging from 228.1 ± 3.8 to 218.2 ± 3.7 Ma. In contrast, muscovites from various schists show slightly older 40Ar/39Ar plateau ages of 236.1 ± 1.5 to 230.2 ± 1.2 Ma. These geochronological and petrological data conclude that the pelitic sediments have experienced a metamorphic event at the Mid-Late Triassic (236.1-218.2 Ma) rather than the Paleoproterozoic (1950-1850 Ma), commonly regarded as the Precambrian basement for the Jiao-Liao-Ji Belt. Hence, the Changhai metamorphic complex should be considered as a discrete

  3. Tang Wang Ming Mu Granule Attenuates Diabetic Retinopathy in Type 2 Diabetes Rats

    Science.gov (United States)

    Chen, Mingxia; Lv, Haibo; Gan, Jiakuan; Ren, Junguo; Liu, Jianxun

    2017-01-01

    Aims: This study aimed to determine the influence of Tang Wang Ming Mu granule (TWMM) on the diabetic retinopathy of diabetic rats. Methods: Male Wistar rats were divided into seven groups: normal control, diabetes model(DM), diabetes with TWMM (3.6, 7.2, and 14.4 g/kg) treatment, the positive control treatment groups of Qi Ming granules and Calcium dobesilate capsules. All rats were treated for 8 weeks. The levels of body weight, fasting blood glucose (FBG) and glycosylated hemoglobin (HbA1c) in blood were measured to evaluate the antihyperglycemic activity of TWMM. Furthermore, malondialdehyde (MDA), intracellular adhesion molecule-1 (ICAM-1) and vascular endothelial growth factor (VEGF) in serum were measured to study effects of TWMM on oxidative stress and inflammatory in DM2 rats. VEGF, JAK/STAT signaling pathway and SOCS3 in retina was detected by immunohistochemistry. Results: TWMM and the positive control drugs Qi Ming and Calcium dobesilate showed a remarkable suppression of retinal neovascularization and amelioration of retinal internal limiting membrane morphology. Moreover, TWMM significantly decreased HbA1c, MDA, ICAM-1, and VEGF levels in serum of diabetic rats. However, Qi Ming granules showed significantly reduced MDA and VEGF levels (P dobesilate showed significantly reduced MDA and ICAM-1levels (P dobesilate significantly increased SOCS3 in retina. Conclusion: Our data suggest that the diabetic retina protective effect of TWMM might be related to antiinflammatory, antioxidative, upregulation of SOCS3 expression, inhibition of the JAK/STAT/VEGF signaling pathway. PMID:29311988

  4. Tang Wang Ming Mu Granule Attenuates Diabetic Retinopathy in Type 2 Diabetes Rats

    Directory of Open Access Journals (Sweden)

    Mingxia Chen

    2017-12-01

    Full Text Available Aims: This study aimed to determine the influence of Tang Wang Ming Mu granule (TWMM on the diabetic retinopathy of diabetic rats.Methods: Male Wistar rats were divided into seven groups: normal control, diabetes model(DM, diabetes with TWMM (3.6, 7.2, and 14.4 g/kg treatment, the positive control treatment groups of Qi Ming granules and Calcium dobesilate capsules. All rats were treated for 8 weeks. The levels of body weight, fasting blood glucose (FBG and glycosylated hemoglobin (HbA1c in blood were measured to evaluate the antihyperglycemic activity of TWMM. Furthermore, malondialdehyde (MDA, intracellular adhesion molecule-1 (ICAM-1 and vascular endothelial growth factor (VEGF in serum were measured to study effects of TWMM on oxidative stress and inflammatory in DM2 rats. VEGF, JAK/STAT signaling pathway and SOCS3 in retina was detected by immunohistochemistry.Results: TWMM and the positive control drugs Qi Ming and Calcium dobesilate showed a remarkable suppression of retinal neovascularization and amelioration of retinal internal limiting membrane morphology. Moreover, TWMM significantly decreased HbA1c, MDA, ICAM-1, and VEGF levels in serum of diabetic rats. However, Qi Ming granules showed significantly reduced MDA and VEGF levels (P < 0.01, and P < 0.05, respectively, Calcium dobesilate showed significantly reduced MDA and ICAM-1levels (P < 0.01 and P < 0.05, respectively in serum. All drug- treated DM2 rats showed significantly lower levels of VEGF, JAK2, P-JAK2, STAT3, and P-STAT3 in retina than DM group, while TWMM and Calcium dobesilate significantly increased SOCS3 in retina.Conclusion: Our data suggest that the diabetic retina protective effect of TWMM might be related to antiinflammatory, antioxidative, upregulation of SOCS3 expression, inhibition of the JAK/STAT/VEGF signaling pathway.

  5. [Effect of strengthening solar ultraviolet B band irradiation on oat (Avena sativa L. ) yield and its components in Qing Tibetan Plateau].

    Science.gov (United States)

    Wang, Sheng-Yao; Wang, Kun; Zhao, Yong-Lai; Xin, You-Jun

    2009-08-01

    Stratospheric ozone depletion occurs mainly over polar regions during the spring when the solar Ultraviolet B-band (280-315 nm, UV-B) radiation is most intense in a year, but over the Qing Tibetan Plateau region, the highest intensity is from June to September when the amount of UV-B radiation reaching the regions is more than that in the adjacent areas lying in the same latitude by 10%. From June to September is just the time of plant's germination, development, and reproduction in the alpine region. UV-B radiation may alter the reproduction of the forage plant, oat (Avena sativa.), which plays the vital role in developing indigenous herdsman's animal husbandry industry. The responses of oat yield and its components to the enhanced ultraviolet B band irradiation under the field condition were surveyed. The effect shows that the grain yield is decreased significantly by strengthened UV-B irradiation, and at the same time the main consequence is the decrease in both the number of ears per square meter and the number of grains per ear, but the weight of 1 000 grains appears not significantly different. Compared with the same respective location in a spikelet, the grain weight is decreased significantly under the treated condition, mostly because of the decreases in the number of the third and forth floret grain and the grain weight at those respective positions, and the percentage of the first and second floret grain and their weight are evidently approved on the contrary.

  6. Letter to the Editor in response to "Our unrequited love for natural ingredients," by Burdock and Wang.

    Science.gov (United States)

    Harman, Christie L; Taylor, Sean V

    2018-01-01

    This letter is in response to the review article "Our unrequited love for natural ingredients" authored by Burdock and Wang in the September edition of FCT. Our purpose is to clarify the procedure used by the FEMA Expert Panel for the safety evaluation of natural flavor complexes, as well as to note and/or correct inaccuracies that we have identified within the article. Copyright © 2017. Published by Elsevier Ltd.

  7. Becoming an International Scientist in South Korea: Ho Wang Lee’s Research Activity about Epidemic Hemorrhagic Fever

    Directory of Open Access Journals (Sweden)

    Miyoung SHIN

    2017-04-01

    Full Text Available In the 1960-70s, South Korea was still in the position of a science latecomer. Although the scientific research environment in South Korea at that time was insufficient, there was a scientist who achieved outcomes that could be recognized internationally while acting in South Korea. He was Ho Wang Lee(1928~ who found Hantann Virus that causes epidemic hemorrhagic fever for the first time in the world. It became a clue to identify causative viruses of hemorrhagic diseases that were scattered here and there throughout the world. In addition, these outcomes put Ho Wang Lee on the global center of research into epidemic hemorrhagic fever. This paper examines how a Korean scientist who was in the periphery of virology could go into the central area of virology. Also this article shows the process through which the virus found by Ho Wang Lee was registered with the international academia and he proceeded with follow-up research based on this progress to reach the level at which he generalized epidemic hemorrhagic fever related studies throughout the world. While he was conducting the studies, experimental methods that he had never experienced encountered him as new difficulties. He tried to solve the new difficulties faced in his changed status through devices of cooperation and connection. Ho Wang Lee’s growth as a researcher can be seen as well as a view of a researcher that grew from a regional level to an international level and could advance from the area of non-mainstream into the mainstream. This analytic tool is meaningful in that it can be another method of examining the growth process of scientists in South Korea or developing countries.

  8. Fasting Plasma Insulin at 5 Years of Age Predicted Subsequent Weight Increase in Early Childhood over a 5-Year Period-The Da Qing Children Cohort Study.

    Directory of Open Access Journals (Sweden)

    Yan Yan Chen

    Full Text Available The association between hyperinsulinemia and obesity is well known. However, it is uncertain especially in childhood obesity, if initial fasting hyperinsulinemia predicts obesity, or obesity leads to hyperinsulinemia through insulin resistance.To investigate the predictive effect of fasting plasma insulin on subsequent weight change after a 5-year interval in childhood.424 Children from Da Qing city, China, were recruited at 5 years of age and followed up for 5 years. Blood pressure, anthropometric measurements, fasting plasma insulin, glucose and triglycerides were measured at baseline and 5 years later.Fasting plasma insulin at 5 years of age was significantly correlated with change of weight from 5 to 10 years (ΔWeight. Children in the lowest insulin quartile had ΔWeight of 13.08±0.73 kg compare to 18.39±0.86 in the highest insulin quartile (P<0.0001 in boys, and similarly 12.03±0.71 vs 15.80±0.60 kg (P<0.0001 in girls. Multivariate analysis showed that the predictive effect of insulin at 5 years of age on subsequent weight gain over 5 years remained statistically significant even after the adjustment for age, sex, birth weight, TV-viewing time and weight (or body mass index at baseline. By contrast, the initial weight at 5 years of age did not predict subsequent changes in insulin level 5 years later. Children who had both higher fasting insulin and weight at 5 years of age showed much higher levels of systolic blood pressures, fasting plasma glucose, the homeostasis model assessment for insulin resistance (HOMA-IR and triglycerides at 10 years of age.Fasting plasma insulin at 5 years of age predicts weight gain and cardiovascular risk factors 5 year later in Chinese children of early childhood, but the absolute weight at 5 years of age did not predict subsequent change in fasting insulin.

  9. Relation between developmental stage, sensory properties, and volatile content of organically and conventionally grown pac choi (Brassica rapa var. Mei Qing Choi).

    Science.gov (United States)

    Talavera-Bianchi, Martin; Adhikari, Koushik; Chambers, Edgar; Carey, Edward E; Chambers, Delores H

    2010-05-01

    This study was conducted to identify and quantify the sensory characteristics and chemical profile of organically and conventionally grown pac choi (Brassica rapa var. Mei Qing Choi), also called bok choy, at 3 stages of growth (2.5, 4.5, and 6.5 wk). Sensory and instrumental data were correlated using partial least squares regression. Pac choi was grown in late spring. Descriptive sensory analysis was conducted by a highly trained panel and compounds were identified and quantified using a gas chromatograph/mass spectrometer. The findings of the study indicate that the differences in sensory characteristics and chemical profiles among stages of growth are more substantial than the differences between organic and conventional production. Green-unripe, musty/earthy, lettuce, and sweet flavors are representative in pac choi at early stages of growth. When older, pac choi has higher intensities of green-grassy/leafy, bitter, cabbage, and sulfur flavors that are associated with the increase of (Z)-3-hexen-1-ol, octyl acetate, 1-nonanol, 2-decanone, 1-penten-3-ol, linalool, camphor, menthol, isobornyl acetate, geranylacetone, and cedrol compounds. Conventional pac choi was higher than organic pac choi in green overall, bitter, and soapy flavors only at 2.5 wk of age. This may be associated with the presence of (Z)-3-hexenal, 2-hexyn-1-ol, and (E)-2-hexenal compounds. The increased popularity of organic production has amplified the need for research that will help in understanding how this production system affects the final quality of food products. This study suggests that the stage of development has a much larger impact on sensory quality than organic or conventional growing of pac choi. Findings from this study promote consumer choice by showing that comparable sensory quality can be obtained using either production system, making the ultimate choice not only based on sensory quality but consumer choice related to environmental beliefs or economics.

  10. Comment on "Parametric Instability Induced by X-Mode Wave Heating at EISCAT" by Wang et al. (2016)

    Science.gov (United States)

    Blagoveshchenskaya, N. F.; Borisova, T. D.; Yeoman, T. K.

    2017-12-01

    In their recent article Wang et al. (2016) analyzed observations from EISCAT (European Incoherent Scatter) Scientific Association Russian X-mode heating experiments and claimed to explain the potential mechanisms for the parametric decay instability (PDI) and oscillating two-stream instability (OTSI). Wang et al. (2016) claim that they cannot separate the HF-enhanced plasma and ion lines excited by O or X mode in the EISCAT UHF radar spectra. Because of this they distinguished the parametric instability excited by O-/X-mode heating waves according to their different excitation heights. Their reflection heights were determined from ionosonde records, which provide a rough measure of excitation altitudes and cannot be used for the separation of the O- and X-mode effects. The serious limitation in their analysis is the use of a 30 s integration time of the UHF radar data. There are also serious disagreements between their analysis and the real observational facts. The fact is that it is the radical difference in the behavior of the X- and O-mode plasma and ion line spectra derived with a 5 s resolution, which provides the correct separation of the X- and O-mode effects. It is not discussed and explained how the parallel component of the electric field under X-mode heating is generated. Apart from the leakage to the O mode, results by Wang et al. (2016) do not explain the potential mechanisms for PDI and OTSI and add nothing to understanding the physical factors accounting for the parametric instability generated by an X-mode HF pump wave.

  11. ¿Cómo podemos usar el móvil para comunicarnos mediante el pensamiento? Entrevista con Yijun Wang

    Directory of Open Access Journals (Sweden)

    Ángel Correa

    2011-01-01

    Full Text Available Un equipo de neurocientíficos ha desarrollado una interfaz cerebro ordenador basada en un teléfono móvil. Las personas con movilidad reducida podrían beneficiarse de este innovador sistema en un futuro próximo. En el experimento que aparece en la fotografía de portada, el participante utiliza únicamente su pensamiento para marcar un número de teléfono. Ciencia Cognitiva ha entrevistado al Dr. Yijun Wang, ingeniero biomédico de la Universidad de California en San Diego, que trabaja en este proyecto.

  12. 2-(p-Hydroxybenzylindoles - Side Products Formed Upon Cleavage of Indole Derivatives from Carboxylated Wang Polymer - an NMR Study

    Directory of Open Access Journals (Sweden)

    Jarl E.S. Wikberg

    2003-10-01

    Full Text Available Treatment of carboxylated Wang polymer attached to a 2-unsubstituted indole derivative with a trifluoroacetic acid based mixture resulted in a side reaction: p-hydroxybenzylation at the 2-position of the indole ring. The structure of the resulting N-3-aminopropyl-N-benzyl-4-[2-(4-hydroxybenzyl-1H-indol-3-yl]-butyramide trifluoroacetate was ascertained by a full assignment of its 1H- and 13C-NMR spectra. The side reaction could be suppressed by the use of 1,2-ethanedithiol in high concentrations (16 %.

  13. An LC-MS/MS method for the simultaneous determination and pharmacokinetic studies of bergenin, chlorogenic acid and four flavonoids in rat plasma after oral administration of a QingGanSanJie decotion extract.

    Science.gov (United States)

    Zhao, Liang; Qian, Xian; Li, Wuhong; Lv, Lei; Zhang, Hai; Chai, Yifeng; Zhang, Guoqing

    2014-12-01

    A rapid, simple and sensitive, liquid chromatography-tandem mass spectrometry (LC-MS/MS) method was developed and validated for simultaneous determination of bergenin, chlorogenic acid and four flavonoids in a QingGanSanJie preparation in rat plasma. Puerarin was selected as the internal standard (IS). Plasma samples were precipitated with methanol and separated with a reverse phase Agilent Poroshell 120 EC-C18 column using a gradient mobile phase of methanol-water containing 0.1% formic acid (v/v). A triple quadruple mass spectrometer was used for quantification (limit of detection 0.36-5.55 ng/mL). Intra-day and inter-day precisions were within 15% and the average extraction recoveries ranged from 85 to 115% for each analyte. The method allowed simultaneous quantification for the first time of the pharmacokinetics of bergenin, chlorogenic acid and four flavonoids after intragastric administration of a QingGanSanJie extract in Sprague-Dawley rats. It was found that bergenin and chlorogenic acid had typical extravascular administration concentration-time curves; flavonoids had a bimodal distribution improving bioavailability and extending the pharmacodynamics period. Copyright © 2014 John Wiley & Sons, Ltd.

  14. All-atom simulation study of protein PTH(1-34) by using the Wang-Landau sampling method

    Science.gov (United States)

    Kim, Seung-Yeon; Kwak, Wooseop

    2014-12-01

    We perform simulations of the N-terminal 34-residue protein fragment PTH(1-34), consisting of 581 atoms, of the 84-residue human parathyroid hormone by using the all-atom ECEPP/3 force field and the Wang-Landau sampling method. Through a massive high-performance computation, the density of states and the partition function Z( T), as a continuous function of T, are obtained for PTH(1-34). From the continuous partition function Z( T), the partition function zeros of PTH(1-34) are evaluated for the first time. From both the specific heat and the partition function zeros, two characteristic transition temperatures are obtained for the all-atom protein PTH(1-34). The higher transition temperature T 1 and the lower transition temperature T 2 of PTH(1-34) can be interpreted as the collapse temperature T θ and the folding temperature T f , respectively.

  15. Smoke (Paul Auster et Wayne Wang, 1995 : une œuvre à la croisée des arts

    Directory of Open Access Journals (Sweden)

    Delphine Letort

    2011-04-01

    Full Text Available The adaptation of the short story entitled “Auggie Wren’s Christmas Story” (1990 gathered the writer Paul Auster and the director Wayne Wang around a film project that allowed them to share their artistic practices in a collaborative work. This paper examines the question that underpins the narrative of the short-story by grappling with the appropriations of the real in other artistic modes. Paul Auster’s first encounter with the cinema points out the convergence between aural writing and cinematic writing, evoked through the double figure of the writer and that of the tale-teller/photographer in both the film and the short story.L’adaptation de la nouvelle « Auggie Wren’s Christmas Story » (1990 réunit l’écrivain Paul Auster et le réalisateur Wayne Wang autour d’un projet qui leur permit de croiser leurs pratiques artistiques dans un travail de collaboration. Cet article prolonge le questionnement artistique qui sous-tend le récit de la nouvelle en interrogeant les modalités de l’appropriation du réel par d’autres arts. La première rencontre entre Paul Auster et le cinéma met en relief les points de convergence entre écriture verbale et écriture cinématographique, évoqués autour de la double figure de l’écrivain et du conteur/photographe dans le film et dans la nouvelle.

  16. H.E. Professor Wang Liheng, Minister of Aviation of the People's Republic of China, President, China Aerospace Science & Technology Corporation

    CERN Multimedia

    Patrice Loïez

    2001-01-01

    H. E. Professor Wang Liheng, Minister of Aviation, and President, China Aerospace Science & Technology Corporation, People's Republic of China (2nd from left) with (from left to right) Professor Hans Hofer, Professor Roger Cashmore, Research Director for Collider Programmes, Professor Samuel C. C. Ting, CERN and Professor Lei Gang, Secretary to the Minister, September 2001.

  17. 清前期宫廷西洋科学仪器的种类和来源/Types and Sources of Scientific Instruments in the Imperial Court of the Early Qing Dynasty

    Directory of Open Access Journals (Sweden)

    Fuxiang GUO

    2015-12-01

    Since the late Ming and the early Qing Dynasty, a far-reaching wave of cultural exchange was formed by Christian missionaries, with Jesuits as the mainstay. This exchange is different from previous ones in that science becomes the most important medium connecting the west and China. A comprehensive examination of this sino-western exchange shows that if lay communication is believed to be dominated by religion and science, the imperial court was turned into an arena where Chinese emperors utilized western science and techniques. It is for this reason that the Palace Museum has housed a considerable collection of western scientific instruments. This paper presents a comparatively full introduction to the collection and an exploration into the collection process by reviewing documents and physical objects.

  18. All-atom simulation study of protein PTH(1-34) by using the Wang-Landau sampling method

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Seung-Yeon [Korea National University of Transportation, Chungju (Korea, Republic of); Kwak, Woo-Seop [Chosun University, Gwangju (Korea, Republic of)

    2014-12-15

    We perform simulations of the N-terminal 34-residue protein fragment PTH(1-34), consisting of 581 atoms, of the 84-residue human parathyroid hormone by using the all-atom ECEPP/3 force field and the Wang-Landau sampling method. Through a massive high-performance computation, the density of states and the partition function Z(T), as a continuous function of T, are obtained for PTH(1-34). From the continuous partition function Z(T), the partition function zeros of PTH(1-34) are evaluated for the first time. From both the specific heat and the partition function zeros, two characteristic transition temperatures are obtained for the all-atom protein PTH(1-34). The higher transition temperature T{sub 1} and the lower transition temperature T{sub 2} of PTH(1-34) can be interpreted as the collapse temperature T{sub θ} and the folding temperature T{sub f} , respectively.

  19. Wang--Landau algorithm for entropic sampling of arch-based microstates in the volume ensemble of static granular packings

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    D. Slobinsky

    2015-03-01

    Full Text Available We implement the Wang-Landau algorithm to sample with equal probabilities the static configurations of a model granular system. The "non-interacting rigid arch model" used is based on the description of static configurations by means of splitting the assembly of grains into sets of stable arches. This technique allows us to build the entropy as a function of the volume of the packing for large systems. We make a special note of the details that have to be considered when defining the microstates and proposing the moves for the correct sampling in these unusual models. We compare our results with previous exact calculations of the model made at moderate system sizes. The technique opens a new opportunity to calculate the entropy of more complex granular models. Received: 19 January 2015, Accepted: 25 February 2015; Reviewed by: M. Pica Ciamarra, Nanyang Technological University, Singapore; Edited by: C. S. O'Hern; DOI: http://dx.doi.org/10.4279/PIP.070001 Cite as: D Slobinsky, L A Pugnaloni, Papers in Physics 7, 070001 (2015

  20. VizieR Online Data Catalog: Multicolor photometry of 135 star clusters in M31 (Wang+, 2012)

    Science.gov (United States)

    Wang, S.; Ma, J.; Fan, Z.; Wu, Z.; Zhang, T.; Zou, H.; Zhou, X.

    2014-01-01

    The sample of star clusters in this paper is selected from Caldwell et al. (2009, cat. J/AJ/137/94; 2011, cat. J/AJ/141/61). Our multicolor photometric data are from the GALEX FUV and NUV, broadband UBVRI, SDSS ugriz, 15 intermediate-band filters of Beijing-Arizona-Taipei-Connecticut (BATC) Multicolor Sky Survey, and 2MASS JHKs, which constitute the Spectral Energy Distributions (SEDs) covering 1538-20000Å. The M31 field is part of a galaxy calibration program of Beijing-Arizona-Taipei-Connecticut (BATC) Multicolor Sky Survey (Zhou et al., 1995-2005, cat. II/262). The BATC program uses the 60/90cm Schmidt Telescope at the Xinglong Station of the National Astronomical Observatories, Chinese Academy of Sciences (NAOC). This system includes 15 intermediate-band filters, covering a range of wavelength from 3000 to 10000Å (see Fan et al., 1996, cat. J/AJ/112/628, for details). Before 2006 February, a Ford Aerospace 2k*2k thick CCD camera was applied, which has a pixel size of 15μm and a field of view of 58'*58', resulting in a resolution of 1.67"/pixel. After 2006 February, a new 4k*4k CCD with a pixel size of 12μm was used, with a resolution of 1.36"/pixel (Fan et al., 2009RAA.....9..993F). We obtained 143.9hr of imaging of the M31 field covering about 6deg2, consisting of 447 images, through the set of 15 filters in five observing runs from 1995 to 2008, spanning 13 years (see Fan et al., 2009RAA.....9..993F; Wang et al., 2010, cat. J/AJ/139/1438, for details). (3 data files).

  1. Epigenetic battle of the sexes. Comment on: ;Epigenetic game theory: How to compute the epigenetic control of maternal-to-zygotic transition; by Qian Wang et al.

    Science.gov (United States)

    Wu, Song

    2017-03-01

    Qian Wang et al. present an interesting framework, named epigenetic game theory, for modeling sex-based epigenetic dynamics during embryogenesis from a new viewpoint of evolutionary game theory [1]. That is, epigenomes of sperms and oocytes may coordinate through either cooperation or competition, or both, to affect the fitness of embryos. The work uses a set of ordinary differential equations (ODEs) to describe longitudinal trajectories of DNA methylation levels in both parental and maternal gametes and their dependence on each other. The insights gained from this review, i.e. dynamic methylation profiles and their interaction are potentially important to many fields, such as biomedicine and agriculture.

  2. P/Ge-Wang joins P/Slaughter-Burnham and P/Boethin in the club of comets in 1/1 resonance with Jupiter

    Science.gov (United States)

    Benest, Daniel G.

    Three comets are now known to be at or near the 1/1 resonance with Jupiter: P/Slaughter-Burnham, P/Boethin and the newly discovered P/Ge-Wang. Their orbital evolutions are compared, using the elliptic three-dimensional restricted three-body model sun-Jupiter-comet. Although details of the individual orbits differ, the three comets have very similar general dynamical behaviors, and stay during a long time at or near the 1/1 resonance, at least for several thousand years.

  3. Grateloupia tenuis Wang et Luan sp. nov. (Halymeniaceae, Rhodophyta: A New Species from South China Sea Based on Morphological Observation and rbcL Gene Sequences Analysis

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    Ling Yu

    2013-01-01

    Full Text Available Grateloupia tenuis Wang et Luan sp. nov. is a new species described from Lingshui, Hainan Province, South China Sea. Based on the external form and internal structure, combined with rbcL gene sequence analysis, Grateloupia tenuis is distinct from other Grateloupia species as follows: (1 thalli is slippery and cartilaginous in texture; possess fewer branches, relatively slight main axes, and two or three dichotomous branches; (2 cortex is 5-6 layers; medulla is solid when young, but hollow in old branches; reproductive structures are dispersed in main axes of thalli and lower portions of branchlets; exhibits Grateloupia-type auxiliary cell ampullae; (3 the four studied G. tenuis sequences were positioned in a large Grateloupia clade of Halymeniaceae, which included sister group generitype G. filicina with 68 bp differences; G. tenuis was determined to be a sister taxon to the G. catenata, G. ramosissima, G. orientalis, and G. filiformis subclade. The pairwise distances between G. tenuis and these species were 39 to 50 bp. The sequences of G. tenuis differed by 81–108 bp from the sequences of other samples in Grateloupia; there are 114–133 bp changes between G. tenuis and other genera of Halymeniaceae. In final analysis, we considered Grateloupia tenuis Wang et Luan sp. nov. to be a new species of genus Grateloupia.

  4. Grateloupia ramosa Wang & Luan sp. nov. (Halymeniaceae, Rhodophyta), a new species from China based on morphological evidence and comparative rbcL sequences

    Science.gov (United States)

    Cao, Cuicui; Liu, Miao; Guo, Shaoru; Zhao, Dan; Luan, Rixiao; Wang, Hongwei

    2016-03-01

    Grateloupia ramosa Wang & Luan sp. nov. (Halymeniaceae, Rhodophyta) is newly described from Hainan Province, southern China. The organism has the following morphological features: (1) purplish red, cartilaginous and lubricous thalli 5-10 cm in height; (2) compressed percurrent axes bearing abundant branches with opposite arrangement; (3) claw-like apices on top, constricted to 2-4 cm at the base; (4) cortex consisting of 3-6 layers of elliptical or anomalous cells and a medulla covered by compact medullary filaments; (5) reproductive structures distributed throughout the thallus, especially centralized at the bottom of the end portion of the branches; and (6) 4-celled Carpogonial branches and 3-celled auxiliary-cell branches, both of the Grateloupia-type. The morphological diff erences were supported by molecular phylogenetics based on ribulose-1, 5-bisphosphate carboxylase/oxygenase ( rbcL) gene sequence analysis. There was only a 1 bp divergence between specimens collected from Wenchang and Lingshui of Hainan province. The new species was embedded in the large Grateloupia clade of the Halymeniaceae. The pairwise distances between G. ramosa and other species within Grateloupia ranged from 26 to 105 bp, within pairwise distances of 13-111 bp between species of the large genus Grateloupia in Halymeniaceae. Thus, we propose this new species as G. ramosa Wang & Luan sp. nov.

  5. Grateloupia tenuis Wang et Luan sp. nov. (Halymeniaceae, Rhodophyta): a new species from South China Sea based on morphological observation and rbcL gene sequences analysis.

    Science.gov (United States)

    Yu, Ling; Wang, Hongwei; Luan, Rixiao

    2013-01-01

    Grateloupia tenuis Wang et Luan sp. nov. is a new species described from Lingshui, Hainan Province, South China Sea. Based on the external form and internal structure, combined with rbcL gene sequence analysis, Grateloupia tenuis is distinct from other Grateloupia species as follows: (1) thalli is slippery and cartilaginous in texture; possess fewer branches, relatively slight main axes, and two or three dichotomous branches; (2) cortex is 5-6 layers; medulla is solid when young, but hollow in old branches; reproductive structures are dispersed in main axes of thalli and lower portions of branchlets; exhibits Grateloupia-type auxiliary cell ampullae; (3) the four studied G. tenuis sequences were positioned in a large Grateloupia clade of Halymeniaceae, which included sister group generitype G. filicina with 68 bp differences; G. tenuis was determined to be a sister taxon to the G. catenata, G. ramosissima, G. orientalis, and G. filiformis subclade. The pairwise distances between G. tenuis and these species were 39 to 50 bp. The sequences of G. tenuis differed by 81-108 bp from the sequences of other samples in Grateloupia; there are 114-133 bp changes between G. tenuis and other genera of Halymeniaceae. In final analysis, we considered Grateloupia tenuis Wang et Luan sp. nov. to be a new species of genus Grateloupia.

  6. Origin discrimination and quality evaluation of Gastrodiae rhizoma ...

    African Journals Online (AJOL)

    Medicine, Chengdu, 610075, 3Life Science & Engineering College of South-west Jiao-tong University, Chengdu, ... quality control and origin discrimination of Gastrodiae rhizoma. ..... Wang Y, Bai G, Luo G. Identification of nuclear factor-κB.

  7. 王弼《老子注》的詮釋辨證/ Interpretative Dialectics of Wang Bi’s Exegesis of Lao-Tzu

    Directory of Open Access Journals (Sweden)

    Jung-Tao TSAI

    2012-09-01

    Wang Bi, the most prominent scholar of metaphysics of the Wei and Jin Dynasties, was an unprecedented genius throughout the history of Chinese philosophy. In this article, the author examines the brilliant contributions made by Lin Li Zhen, Yu Dun Kang and Rudolf G. Wagner, who are noticed for their research of Exegesis of Lao-Tzu. It is a synthesis of the directions of investigation, approaches, and significant findings they have come up with. Among the three interpretations, Lin focuses on the explanation of Wang’s metaphysic thinking while Yu emphasizes Wang’s secular concerns by proposing the “philosophy of thoroughness” and political holism. As for Wagner, he approaches this work with the views of linguistic philosophy and suggests refined stylistics as interpretative strategy, which functions to enrich the textual contents.

  8. De Hemingway au chinois classique : le travail de la langue de l’écrivain taïwanais Wang Wen-hsing

    Directory of Open Access Journals (Sweden)

    Sandrine Marchand

    2014-04-01

    Full Text Available Dans les années 1970, l’« occidentalisation » de Wang Wen-hsing lui attire les foudres de la critique. On lui reproche, entre autres choses, de mal écrire, d’être incompréhensible et d’écrire dans une langue occidentalisée. Lui-même semble prendre pour modèle son professeur de français, dont le niveau de chinois classique était très élevé. Entre chinois classique, moderne, dialecte de sa région natale (très proche du dialecte de Taïwan, anglais, et français idéalisé, Wang Wen-hsing invente sa propre langue. Dans les manuscrits de son premier roman, il recourt au syllabaire que les enfants utilisent en cours d’apprentissage de la langue chinoise pour remplacer les caractères d’écriture, syllabaire qui disparaît ensuite à la publication. Que nous apprend l’utilisation de ce syllabaire sur le travail créatif de l’auteur ?Wang Wen-hsing est un auteur qui, entre extrême précision et violence, consacre sa vie et toute son énergie au travail de la langue. Quelle langue tente-t-il d’approcher : le chinois normatif des temps anciens, la langue américaine de Hemingway, ou un mélange des deux ?Multilingue à l’intérieur de la langue chinoise moderne, elle-même langue encore proche du chinois classique, abandonné seulement au début du xxe siècle, l’écriture romanesque de Wang Wen-hsing, qui a pour critère de valeur le « tong-shun » (clarté et aisance, est le fruit de l’oralité et d’une langue expérimentale. Ce rapport à la langue vient-il de sa situation d’émigration, de son isolement des milieux politiques et intellectuels, comme cela lui a été reproché lorsque justement on l’accusait d’écrire dans une langue incompréhensible pour le lecteur ? Pourquoi ces romans sont-ils jugés incompréhensibles ? En raison du niveau du lecteur moyen ? Pour des raisons géopolitiques, car il est un émigré en position dominante dans l’île ? Parce que la langue chinoise est dans

  9. A new concept: Epigenetic game theory. Comment on: ;Epigenetic game theory: How to compute the epigenetic control of maternal-to-zygotic transition; by Qian Wang et al.

    Science.gov (United States)

    Zheng, Xiu-Deng; Tao, Yi

    2017-03-01

    The evolutionary significance of the interaction between paternal and maternal genomes in fertilized zygotes is a very interesting and challenging question. Wang et al. developed the concept of epigenetic game theory, and they try to use this concept to explain the interaction between paternal and maternal genomes in fertilized zygotes [1]. They emphasize that the embryogenesis can be considered as an ecological system in which two highly distinct and specialized gametes coordinate through either cooperation or competition, or both, to maximize the fitness of embryos under Darwinian selection. More specifically, they integrate game theory to model the pattern of coordination of paternal genome and maternal genomes mediated by DNA methylation dynamics, and they called this epigenetic game theory.

  10. Effects of Chinese materia medica-fuboa danggui jiao on ...

    African Journals Online (AJOL)

    The implants and normal uterine horns were removed for routine histological examination. FDJ caused significant decreases in volumes of the surviving endometriotic implants, with two different doses having statistically equivalent effects. Upon histological examination, FDJ was observed to cause regression of epithelium ...

  11. The impact of an underground cut-off wall on nutrient dynamics in groundwater in the lower Wang River watershed, China.

    Science.gov (United States)

    Kang, Pingping; Xu, Shiguo

    2017-03-01

    Underground cut-off walls in coastal regions are mainly used to prevent saltwater intrusion, but their impact on nutrient dynamics in groundwater is not clear. In this study, a combined analysis of multiple isotopes ([Formula: see text]) and nitrogen and phosphorus concentrations is used in order to assess the impact of the underground cut-off walls on the nutrient dynamics in groundwater in the lower Wang River watershed, China. Compared with the nitrogen and phosphorus concentrations in groundwater downstream of the underground cut-off walls, high [Formula: see text] and total dissolved nitrogen concentrations and similar concentration levels of [Formula: see text] and total dissolved phosphorus are found in groundwater upstream of the underground cut-off walls. The isotopic data indicated the probable occurrence of denitrification and nitrification processes in groundwater upstream, whereas the fingerprint of these processes was not shown in groundwater downstream. The management of fertilizer application is critical to control nitrogen concentrations in groundwater restricted by the underground cut-off walls.

  12. Evaluation of the grand-canonical partition function using expanded Wang-Landau simulations. III. Impact of combining rules on mixtures properties

    Energy Technology Data Exchange (ETDEWEB)

    Desgranges, Caroline; Delhommelle, Jerome [Department of Chemistry, University of North Dakota, 151 Cornell Street Stop 9024, Grand Forks, North Dakota 58202 (United States)

    2014-03-14

    Combining rules, such as the Lorentz-Berthelot rules, are routinely used to calculate the thermodynamic properties of mixtures using molecular simulations. Here we extend the expanded Wang-Landau simulation approach to determine the impact of the combining rules on the value of the partition function of binary systems, and, in turn, on the phase coexistence and thermodynamics of these mixtures. We study various types of mixtures, ranging from systems of rare gases to biologically and technologically relevant mixtures, such as water-urea and water-carbon dioxide. Comparing the simulation results to the experimental data on mixtures of rare gases allows us to rank the performance of combining rules. We find that the widely used Lorentz-Berthelot rules exhibit the largest deviations from the experimental data, both for the bulk and at coexistence, while the Kong and Waldman-Hagler provide much better alternatives. In particular, in the case of aqueous solutions of urea, we show that the use of the Lorentz-Berthelot rules has a strong impact on the Gibbs free energy of the solute, overshooting the value predicted by the Waldman-Hagler rules by 7%. This result emphasizes the importance of the combining rule for the determination of hydration free energies using molecular simulations.

  13. Evaluation of the grand-canonical partition function using expanded Wang-Landau simulations. III. Impact of combining rules on mixtures properties

    Science.gov (United States)

    Desgranges, Caroline; Delhommelle, Jerome

    2014-03-01

    Combining rules, such as the Lorentz-Berthelot rules, are routinely used to calculate the thermodynamic properties of mixtures using molecular simulations. Here we extend the expanded Wang-Landau simulation approach to determine the impact of the combining rules on the value of the partition function of binary systems, and, in turn, on the phase coexistence and thermodynamics of these mixtures. We study various types of mixtures, ranging from systems of rare gases to biologically and technologically relevant mixtures, such as water-urea and water-carbon dioxide. Comparing the simulation results to the experimental data on mixtures of rare gases allows us to rank the performance of combining rules. We find that the widely used Lorentz-Berthelot rules exhibit the largest deviations from the experimental data, both for the bulk and at coexistence, while the Kong and Waldman-Hagler provide much better alternatives. In particular, in the case of aqueous solutions of urea, we show that the use of the Lorentz-Berthelot rules has a strong impact on the Gibbs free energy of the solute, overshooting the value predicted by the Waldman-Hagler rules by 7%. This result emphasizes the importance of the combining rule for the determination of hydration free energies using molecular simulations.

  14. Game theory in epigenetic reprogramming. Comment on: ;Epigenetic game theory: How to compute the epigenetic control of maternal-to-zygotic transition; by Qian Wang et al.

    Science.gov (United States)

    Hsu, Fei-Man; Chen, Pao-Yang

    2017-03-01

    Von Neumann and Morgenstern published the Theory of Games and Economic Behavior in 1944, describing game theory as a model in which intelligent rational decision-makers manage to find their best strategies in conflict, cooperative or other mutualistic relationships to acquire the greatest benefit [1]. This model was subsequently incorporated in ecology to simulate the ;fitness; of a species during natural selection, designated evolutionary game theory (EGT) [2]. Wang et al. proposed ;epiGame;, taking paternal and maternal genomes as ;intelligent; players that compete, cooperate or both during embryogenesis to maximize the fitness of the embryo [3]. They further extended game theory to an individual or single cell environment. During early zygote development, DNA methylation is reprogrammed such that the paternal genome is demethylated before the maternal genome. After the reset, the blastocyst is re-methylated during embryogenesis. At that time, the paternal and maternal genomes have a conflict of interest related to the expression of their own genes. The proposed epiGame models such interactive regulation between the parental genomes to reach a balance for embryo development (equation (2)).

  15. Retraction statement: 'Formin-like2 regulates Rho/ROCK pathway to promote actin assembly and cell invasion of colorectal cancer' by Yuanfeng Zeng, Huijun Xie, Yudan Qiao, Jianmei Wang, Xiling Zhu, Guoyang He, Yuling Li, Xiaoli Ren, Feifei Wang, Li Liang and Yanqing Ding.

    Science.gov (United States)

    2016-07-01

    The above article in Cancer Science (doi: 10.1111/cas.12768), published online on 26 October 2015 in Wiley Online Library (http://wileyonlinelibrary.com), has been retracted by agreement between the authors, the journal Editor in Chief, Yusuke Nakamura, and Wiley Publishing Asia Pty Ltd. The retraction has been agreed as Panels +C3 and +Y27632 of SW480 Mock shown in Figure 2a appear to have been taken from the same image, Panels + C3 and +Y27632 of HT29 FMNL2 shown in Figure 2a appear to have been taken from the same image, Panels shFMNL2-1 and shmDial1-1 in Figure 3a appear to have been taken from the same image, shFMNL2-2 and shmDial1-2 in Figure 3a appear to have been taken from the same image, Panels of shFMNL2-1 + shmDial1-1 and shFMNL2-1 + shmDial1-2 of +LPA appear to have been taken from the same image, gel bands of FLAG in Figure 4e appear to have been have been manipulated by erasing gel bands. Reference Zeng Y, Xie H, Qiao Y, Wang J, Zhu X, He G, Li Y, Ren X, Wang F, Liang L, Ding Y. Formin-like2 regulates Rho/ROCK pathway to promote actin assembly and cell invasion of colorectal cancer. Cancer Sci 2015; 106: 1385-93. doi: 10.1111/cas.12768. © 2016 The Authors. Cancer Science published by John Wiley & Sons Australia, Ltd on behalf of Japanese Cancer Association.

  16. Analisis senyawa volatil dari ekstrak tanaman yang berpotensi sebagai atraktan parasitoid telur wereng batang coklat, Anagrus nilaparvatae (Pang et Wang (Hymenoptera: Mymaridae

    Directory of Open Access Journals (Sweden)

    Surjani Wonorahardjo

    2015-09-01

    Full Text Available Plants produce volatiles as communication cues intra- or inter- species. Infested plants by herbivores will produce volatiles as indirect defense mechanism that attracts natural enemies of herbivores. Analysis of volatiles compounds produced by rice plant as result of infested brown plant hopper (BPH, Nilaparvata lugens Stâl, was done to identify compounds in the volatiles that potentially can be used as attractant for egg parasitoids of BPH, Anagrus nilaparvatae (Pang et Wang (Hymenoptera: Mymaridae. This research was an early stage to develop formulation of parasitoid attractant. The research activities include volatiles extraction of infested rice stem by BPH eggs using acetone, n-hexane as the extraction solvents; analyses of volatile compounds with GC-MS; and bioassay of parasitoid orientation behavior to the volatiles using olfactometer methods. Extraction methods applied were maceration and continuous extraction followed by concentration. Bioassay on the parasitoid orientation behavior was done by using Y-tube olfactometer and every lot of bioassay using 30 parasitoid females with 3 replicates. The results showed that the volatile compounds of extract of infested rice stem by BPH eggs comprise of 16 components. The highest proportion of the components extracted with acetone is 2-Pentanone, 4-hydroxy-4-methyl (19,9%, while those with n-hexane is Hexanedioic acid, dioctyl ester (65%. A. nilaparvatae showed positive response to the volatiles extracted from infested rice plant by N. lugens eggs. Therefore, the volatiles can be used as an attractant for the egg A. nilaparvatae to support rice pest management.

  17. Using game theory to investigate the epigenetic control mechanisms of embryo development. Comment on: ;Epigenetic game theory: How to compute the epigenetic control of maternal-to-zygotic transition; by Qian Wang et al.

    Science.gov (United States)

    Zhang, Le; Zhang, Shaoxiang

    2017-03-01

    A body of research [1-7] has already shown that epigenetic reprogramming plays a critical role in maintaining the normal development of embryos. However, the mechanistic quantitation of the epigenetic interactions between sperms and oocytes and the related impact on embryo development are still not clear [6,7]. In this study, Wang et al., [8] develop a modeling framework that addresses this question by integrating game theory and the latest discoveries of the epigenetic control of embryo development.

  18. A mathematical view for ordinary differential equation models. Comment on ;Epigenetic game theory: How to compute the epigenetic control of maternal-to-zygotic transition; by Qian Wang et al.

    Science.gov (United States)

    Fu, Guifang

    2017-03-01

    Qian Wang et al. have written an interesting article to propose a modeling framework named epiGame in this issue of Physics of Life Reviews [1]. The epiGame framework models how the methylation state of paternal and maternal genomes regulates the embryogenesis as an ecological system in which two highly distinct and specialized gametes coordinate through either cooperation or competition, or both, to maximize the fitness of embryos. Qian Wang et al. also provide solid simulation studies and real data analysis to validate the correctness of their epiGame framework. The importance of embryo development and fertility mechanism cannot be overemphasized, hence, I think that the present review by Qian Wang et al. will stand as a useful modeling guide for practicing biologists or researchers in fertility health to quantify how sperms and oocytes interact through epigenetic process to determine embryo development. In addition, it will serve as a source of many important references to work in the reproductive biology field.

  19. Topological phase transition in the two-dimensional anisotropic Heisenberg model: A study using the Replica Exchange Wang-Landau sampling

    Science.gov (United States)

    Figueiredo, T. P.; Rocha, J. C. S.; Costa, B. V.

    2017-12-01

    Although the topological Berezinskii-Kosterlitz-Thouless transition was for the first time described by 40 years ago, it is still a matter of discussion. It has been used to explain several experiments in the most diverse physical systems. In contrast with the ordinary continuous phase transitions the BKT-transition does not break any symmetry. However, in some contexts it can easily be confused with other continuous transitions, in general due to an insufficient data analysis. The two-dimensional XY (or sometimes called planar rotator) spin model is the fruit fly model describing the BKT transition. As demonstrated by Bramwell and Holdsworth (1993) the finite-size effects are more important in two-dimensions than in others due to the logarithmic system size dependence of the properties of the system. Closely related is the anisotropic two dimensional Heisenberg model (AH). Although they have the same Hamiltonian the spin variable in the former has only two degrees of freedom while the AH has three. Many works treat the AH model as undergoing a transition in the same universality class as the XY model. However, its characterization as being in the BKT class of universality deserve some investigation. This paper has two goals. First, we describe an analytical evidence showing that the AH model is in the BKT class of universality. Second, we make an extensive simulation, using the numerical Replica Exchange Wang-Landau method that corroborate our analytical calculations. From our simulation we obtain the BKT transition temperature as TBKT = 0 . 6980(10) by monitoring the susceptibility, the two point correlation function and the helicity modulus. We discuss the misuse of the fourth order Binder's cumulant to locate the transition temperature. The specific heat is shown to have a non-critical behavior as expected in the BKT transition. An analysis of the two point correlation function at low temperature, C(r) ∝r - η(T), shows that the exponent, η, is consistent

  20. 黃遵憲對晚清引介日本教育制度及建立西式教育的貢獻 Huang Zunxian’s Contribution to the Introduction of Aspects of the Japanese Education System and the Establishment of Western-style Education in Late Qing China

    Directory of Open Access Journals (Sweden)

    周愚文 Yu-Wen Chou

    2014-06-01

    Full Text Available 晚清兩學制係仿日制,而黃遵憲最先完整介紹並建議仿日。他使日時親身經歷明治維新,藉蒐集文獻、代譯書籍、訪談友人及實地參訪等法撰成《日本雜事詩》與《日本國志》,開研究日本先河,提倡設學興教,鼓勵清仿日變法。後書於甲午戰敗後問世,戊戌維新時,皇帝及變法重臣都讀過。梁啟超將《國志》列為時務學堂必讀之書,倡辦師範教育;盛宣懷創南洋公學,首建師範齋及附設小 學;戊戌時康梁議設各級學堂及京師大學堂以統各省學堂等,均當受黃氏啟迪。但因日持續變革,故不易掌握新況。當制定學制時,他雖未參與但擬藉書喚起朝野正視日本之崛起,對引介日制及建立西式教育實有貢獻。可惜主政者未重視,再派員赴日短期考察,歸國後未參與規劃,報告僅供參考,遂無法設計符合國情的新學制。本文旨在探討黃遵憲對引介日本教育及建立新學制的貢獻。 Huang Zunxian was the first Chinese to compile a description of the Japanese education system and to suggest that China should learn from it. While serving as a Chinese diplomat in Japan, Huang witnessed the Meiji Restoration reforms at first hand. The research and investigations that Huang undertook while in Japan provided the basis for his Poems on Japan and General History of Japan; Huang urged the Qing government to implement educational reforms along Japanese lines. The aim of the present study is to examine the contribution made by Huang Zunxian to the introduction of aspects of the Japanese education system into China during the last years of the Qing Dynasty. Huang’s writings influenced other educational reformers such as Sheng Xuanhuai, Kang Youwei and Liang Qichao. However, the Japanese education system itself continued to evolve during this period, which made it difficult for China to keep upto-date with the latest

  1. Efficacy and adequacy of conventional transbronchial needle aspiration of IASLC stations 4R, 4L and 7 using endobronchial landmarks provided by the Wang nodal mapping system in the staging of lung cancer.

    Science.gov (United States)

    Liu, Qinghua; Han, Songyan; Arias, Sixto; Turner, J Francis; Lee, Hans; Browning, Robert; Wang, Ko-Pen

    2016-01-01

    The role of transbronchial needle aspiration (TBNA) in the diagnosis and staging of lung cancer has been well established. Recently, the efficacy of conventional TBNA in the staging of lung cancer has been enhanced by the use of endobronchial ultrasound (EBUS)-TBNA. Our study sought to evaluate the adequacy of TBNA of International Association for the Study of Lung Cancer (IASLC) stations 4R, 4L and 7 using endobronchial landmarks provided by the Wang nodal mapping system in the staging of lung cancer. We retrospectively analyzed all bronchoscopic cases with conventional TBNA punctures positive for malignancy at our institution from 1 January to 31 October 2014. The endobronchial puncture site was guided by the Wang nodal mapping system. The Wang stations were correlated with the IASLC lymph node map. No endobronchial ultrasound or rapid on-site evaluation was used. Pathological analysis included cytological and histological examination. Diagnosis by histological analysis was obtained in 115 (55.3%) out of 208 puncture sites. The metastatic lymph nodes were distributed at IASLC stations 4R (W1, 3, 5) 46.6 %, 7 (W2, 8, 10) 19.7%, 4L (W4, 6) 11.5%, 11R (W7, W9) 11.1% 11L (W11) 9.6%, 2R (high station W3) 0.5%, and the proximal portion of station 8 (station W10 beyond the middle lobe orifice) 1%. No complications were observed. IASLC station 4R (W1, 3, 5), 7 (W2, 8, 10) and 4L (W4, 6) are adequate for the staging of lung cancer.

  2. Epigenetic information in gametes: Gaming from before fertilization. Comment on ;Epigenetic game theory: How to compute the epigenetic control of maternal-to-zygotic transition; by Qian Wang et al.

    Science.gov (United States)

    Shi, Junchao; Zhang, Xudong; Liu, Ying; Chen, Qi

    2017-03-01

    In their interesting article [1] Wang et al. proposed a mathematical model based on evolutionary game theory [2] to tackle the fundamental question in embryo development, that how sperm and egg interact with each other, through epigenetic processes, to form a zygote and direct successful embryo development. This work is based on the premise that epigenetic reprogramming (referring to the erasure and reconstruction of epigenetic marks, such as DNA methylation and histone modifications) after fertilization might be of paramount importance to maintain the normal development of embryos, a premise we fully agree, given the compelling experimental evidence reported [3]. Wang et al. have specifically chosen to employ the well-studied DNA methylation reprogramming process during mammalian early embryo development, as a basis to develop their mathematical model, namely epigenetic game theory (epiGame). They concluded that the DNA methylation pattern in mammalian early embryo could be formulated and quantified, and their model can be further used to quantify the interactions, such as competition and/or cooperation of expressed genes that maximize the fitness of embryos. The efforts by Wang et al. in quantitatively and systematically analyzing the beginning of life apparently hold value and represent a novel direction for future embryo development research from both theoretical and experimental biologists. On the other hand, we see their theory still at its infancy, because there are plenty more parameters to consider and there are spaces for debates, such as the cases of haploid embryo development [4]. Here, we briefly comment on the dynamic process of epigenetic reprogramming that goes beyond DNA methylation, a dynamic interplay that involves histone modifications, non-coding RNAs, transposable elements et al., as well as the potential input of the various types of 'hereditary' epigenetic information in the gametes - a game that has started before the fertilization.

  3. Using game theory to investigate the epigenetic control mechanisms of embryo development: Comment on: "Epigenetic game theory: How to compute the epigenetic control of maternal-to-zygotic transition" by Qian Wang et al.

    Science.gov (United States)

    Zhang, Le; Zhang, Shaoxiang

    2017-03-01

    A body of research [1-7] has already shown that epigenetic reprogramming plays a critical role in maintaining the normal development of embryos. However, the mechanistic quantitation of the epigenetic interactions between sperms and oocytes and the related impact on embryo development are still not clear [6,7]. In this study, Wang et al., [8] develop a modeling framework that addresses this question by integrating game theory and the latest discoveries of the epigenetic control of embryo development. Copyright © 2017 Elsevier B.V. All rights reserved.

  4. Phase formation of superconducting MgB2 at ambient pressure

    Indian Academy of Sciences (India)

    Unknown

    One of the authors (AT) expresses his gratitude to the. Council of Scientific and Industrial Research, New Delhi, for the award of a junior research fellowship. References. Dhalle M, Toulemonde P, Beneduce C, Musolin N, Decroux M and Flukiger R 2001 Physica C363 155. Feng Qing-rong, Wang Xin, Wang Xin-jie and ...

  5. Responses of plant morphology and seed quality to long-term ...

    African Journals Online (AJOL)

    use

    2011-12-14

    Dec 14, 2011 ... Responses of plant morphology and seed quality to long-term overgrazing in Leymus chinensis. Yu-tong Wang1,2#, Bo Deng1#, Kun Wang and Xin-qing Shao1,2*. 1Institute of Grassland Science, Animal and Technology College, China Agricultural University, Beijing 100093, China. 2National field station ...

  6. Green tea polyphenol induces significant cell death in human lung ...

    African Journals Online (AJOL)

    Green tea polyphenol induces significant cell death in human lung cancer cells. Jie Huang, Fa-jiu Li, Shi Chen, Yi Shi, Xiao-jiang Wang, Chuan-hai Wang, Qing- ..... method for the determination of green and black tea polyphenols in biomatrices by high-performance liquid chromatography with coulometric array detection.

  7. Microsatellite analysis of the genetic relationships between wild and ...

    Indian Academy of Sciences (India)

    the large-scale artificial culture of giant grouper has been. ∗For correspondence. E-mail: lsszy@mail.sysu.edu.cn. Qing Wang and Xiang Wang contributed equally to this work. successfully established in China and other Asian countries, alleviating the fishing pressure on wild populations to some extent (Tupper and Sheriff ...

  8. African Journal of Biotechnology - Vol 11, No 30 (2012)

    African Journals Online (AJOL)

    DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. Chunyan Ji, Chunyan Wang, 7618-7628 ... DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. Jian-feng Liu, Yun-qing Cheng, Kun Yan, Qiang Liu, 7670-7675 ... FULL TEXT DOWNLOAD FULL TEXT. Xiuping Wang, Tianxue Liu, Chaohai Li, Hao Chen, 7676-7685 ...

  9. Journal of Chemical Sciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Chemical Sciences. Gen Hua Wu. Articles written in Journal of Chemical Sciences. Volume 121 Issue 4 July 2009 pp 543-548. Highly sensitive optical chemosensor for the detection of Cu using a rhodamine B spirolatam · Gen Hua Wu Dong Xiang Wang Da Yu Wu Yuan Gao Zhu Qing Wang.

  10. Journal of Genetics | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Characterization of novel polymorphic microsatellite markers from the cDNA library of Japanese scallop Mizuhopecten yessoensis and cross-species amplification in bay scallop Argopecten irradians · Xiang Ying Meng Xiu Li Wang Xiao Li Guo Meng Chen Ying Ming Zhang Hong Yue Wang Ya Qing Chang Xue Mei Qiu.

  11. Retraction: Mohamaden W, Wang H, Guan H, Li J. Effect of potassium oxalate on liver function and kidney tissue of dogs (beagles. Arch biol sci. 2013;65(4:1363-70. DOI: 10.2298/ABS1304363M

    Directory of Open Access Journals (Sweden)

    Editorial

    2015-01-01

    Full Text Available This is a notice of retraction of the article: Effect of potassium oxalate on liver function and kidney tissue of dogs (beagles, published in the Archives of Biological Sciences in 2013, Vol. 65, Issue 4. The Editor-in-Chief has been informed that this paper is a duplicate of an earlier paper: Mohamaden W, Wang H, Guan H, Meng X, Li J. Effect of potassium oxalate injection on serum and kidney tissue of beagle dogs. Life Sci J. 2013;10(2:1537-42. This claim is correct and the results have already been presented in the article published earlier. After confirmation of this fact, the Editor-in-Chief of the Archives of Biological Sciences has decided to retract the paper immediately. We apologize for this error. Link to the retracted article 10.2298/ABS1304363M

  12. Retraction: "Activated K-Ras and INK4a/Arf Deficiency Promote Aggressiveness of Pancreatic Cancer by Induction of EMT Consistent With Cancer Stem Cell Phenotype" by Wang et al.

    Science.gov (United States)

    2016-10-01

    The above article, published online on November 23, 2012 in Wiley Online Library (wileyonlinelibrary.com), has been retracted by agreement between the journal Editor in Chief, Gary S. Stein, and Wiley Periodicals, Inc. The retraction has been agreed following an investigation from Wayne State University involving the first author and the corresponding author that found Figure 4B and C to be inappropriately manipulated and re-labeled. Literature Cited Wang Z, Ali S, Banerjee S, Bao B, Li Y, Azmi AS, Korc M, Sarkar FH. 2013. Activated K-Ras and INK4a/Arf deficiency promote aggressiveness of pancreatic cancer by induction of EMT consistent with cancer stem cell phenotype. J Cell Physiol 228:556-562; doi: 10.1002/jcp.24162. © 2016 Wiley Periodicals, Inc.

  13. Retraction: "Identification of Novel Biomarkers for Pancreatic Cancer Using Integrated Transcriptomics With Functional Pathways Analysis" by Zhang, X., Tong, P., Chen, J., Pei, Z., Zhang, X., Chen, W., Xu, J. and Wang, J.

    Science.gov (United States)

    2017-11-01

    The above article from the Journal of Cellular Physiology, published online on 10 March 2016 in Wiley Online Library as Early View (http://onlinelibrary.wiley.com/enhanced/doi/10.1002/jcp.25353/), has been retracted by agreement between Gary Stein, the journal's Editor-in-Chief, and Wiley Periodicals, Inc. The retraction has been agreed following an investigation at the University of Texas, MD Anderson Cancer Center, which confirmed that the article was submitted and approved for publication by Dr. Jin Wang without acknowledgement of NIH funding received or the consent and authorship of Dr. Ann Killary and Dr. Subrata Sen, with whom the manuscript was originally drafted. © 2016 Wiley Periodicals, Inc.

  14. Retraction: "Down-regulation of Notch-1 and Jagged-1 inhibits prostate cancer cell growth, migration and invasion, and induces apoptosis via inactivation of Akt, mTOR, and NF-κB signaling pathways" by Wang et al.

    Science.gov (United States)

    2016-08-01

    The above article, published online on January 5, 2010 in Wiley Online Library (wileyonlinelibrary.com), has been retracted by agreement between the journal Editor in Chief, Gary S. Stein, and Wiley Periodicals, Inc. The retraction has been agreed following an investigation from Wayne State University involving the first author and the corresponding author that found Figure 5A to be inappropriately manipulated. REFERENCE Wang Z, Li Y, Banerjee S, Kong D, Ahmad A, Nogueira V, Hay N, Sarkar FH. 2010. Down-regulation of Notch-1 and Jagged-1 inhibits prostate cancer cell growth, migration and invasion, and induces apoptosis via inactivation of Akt, mTOR, and NF-κB signaling pathways. J Cell Biochem 109:726-736; doi: 10.1002/jcb.22451. © 2016 Wiley Periodicals, Inc.

  15. Retraction: "Down-regulation of Notch-1 is associated with Akt and FoxM1 in inducing cell growth inhibition and apoptosis in prostate cancer cells" by Wang et al.

    Science.gov (United States)

    2016-08-01

    The above article, published online on July 23, 2010 in Wiley Online Library (wileyonlinelibrary.com), has been retracted by agreement between the journal Editor in Chief, Gary S. Stein, and Wiley Periodicals, Inc. The retraction has been agreed following an investigation from Wayne State University involving the first author and the corresponding author that found Figures 1B and 3A to be inappropriately manipulated. REFERENCE Wang Z, Li Y, Ahmad A, Banerjee S, Azmi AS, Kong D, Wojewoda C, Miele L, Sarkar FH. 2011. Down-regulation of Notch-1 is associated with Akt and FoxM1 in inducing cell growth inhibition and apoptosis in prostate cancer cells. J Cell Biochem 112:78-88; doi: 10.1002/jcb.22770. © 2016 Wiley Periodicals, Inc.

  16. 纲目相彰,史论并见--评秦宗财《明清文化传播与商业互动研究:以徽州出版与徽商为中心》%Clear Outline, Clear History and Criticism---A Review on The Research of Business Interaction and Cultural Transmission in the Ming Qing Dynasty, Center for Huizhou Publishing and Merchants by Dr Qin Zongcai

    Institute of Scientific and Technical Information of China (English)

    刘和文

    2016-01-01

    徽州刻书历史悠久,经宋元时期的发展,明清时期的徽州刻书闻名全国,不断发展壮大而成为全国刻书业的领军,涌现出大批优秀成果。秦宗财博士所著《明清文化传播与商业互动研究:以徽州出版与徽商为中心》,在传播学视角下考证了明清徽州出版的特点与影响,揭示了明清文化传播与商业经济互动的内在机制,既是一部研究价值高的徽学著述,又是一部优秀的研究文化传播之著作。%The engraved book has a long history in Huizhou. After the development of Song and Yuan Dynasty, the engraved book has been well-known throughout the country. Furthermore, it becomes a leader of the book carving industry, appears a large number of outstanding works which has been concerned about research. The Research of Business Interaction and Cultural Transmission in the Ming Qing Dynasty, Center for HuiZhou publishing and merchants by Dr. Qin Zongcai, researches the characteristics and influence of Huizhou publishing industry in the Ming and Qing dynasty under the communication perspective, reveals the interactive mechanism between culture communication and commercial economy. This is full of highly research value both for Hui and cultural transmission Study.

  17. News & Views Evaluation of Projects for Basic Research of Scientific Instruments in 2008 Completed NSFC Former President Tang Ao-qing Passed Away Professor Tang Aoqing and NSFC Carbon Nanotube Film-Based Speaker Developed in Tsinghua University Dinosaur Footprint Fossils Discovered in Xinjiang New Method for Early Cancer Diagnosis New Progress Achieved by NSFC Project in Basic Research of Black Hole Physics New progress in Organic FET 67 NSFC-RFBR Cooperative Projects Approved for 2008 Spin Configuration and Super-exchange Mechanism in Molecular Magnets Observed NSFC Strengthens its Funding in Wenchuan Concerns Go to Disaster's Impact on Economy and Emergency Response Thirty-seven NSFC-KOSEF Cooperative Projects Approved

    Science.gov (United States)

    2008-01-01

    Evaluation of Projects for Basic Research of Scientific Instruments in 2008 Completed NSFC Former President Tang Ao-qing Passed Away Professor Tang Aoqing and NSFC Carbon Nanotube Film-Based Speaker Developed in Tsinghua University Dinosaur Footprint Fossils Discovered in Xinjiang New Method for Early Cancer Diagnosis New Progress Achieved by NSFC Project in Basic Research of Black Hole Physics New progress in Organic FET 67 NSFC-RFBR Cooperative Projects Approved for 2008 Spin Configuration and Super-exchange Mechanism in Molecular Magnets Observed NSFC Strengthens its Funding in Wenchuan Concerns Go to Disaster's Impact on Economy and Emergency Response Thirty-seven NSFC-KOSEF Cooperative Projects Approved

  18. Prognostic value of Notch-1 expression in hepatocellular carcinoma: a meta-analysis

    Directory of Open Access Journals (Sweden)

    Wu T

    2015-10-01

    Full Text Available Tao Wu,1 Min Jiao,1 Li Jing,1 Min-Cong Wang,1 Hai-Feng Sun,2 Qing Li,1 Yi-Yang Bai,1 Yong-Chang Wei,1 Ke-Jun Nan,1 Hui Guo1 1Department of Medical Oncology, The First Affiliated Hospital of Xi’an Jiaotong University, 2Department of Oncology, Shaanxi Cancer Hospital, Xi’an, People’s Republic of China Abstract: Association of Notch-1 expression with prognosis of patients with hepatocellular carcinoma (HCC remains controversial. We conducted a meta-analysis to reevaluate the association of Notch-1 expression with clinicopathological characteristics and prognosis of HCC. PubMed, Embase, Web of Science, and China National Knowledge Infrastructure were searched to look for relevant studies. The association between Notch-1 expression and clinicopathological parameters and overall survival (OS was then reassessed using the meta-analysis for odds ratio (OR or hazard ratio (HR and 95% confidence interval (CI. A total of seven studies, including 810 HCC patients, were eligible for the meta-analysis. Our data showed that high Notch-1 expression was able to predict poor OS (HR 1.50, 95% CI 1.17–1.83, P=0.0001. The pooled OR showed that high Notch-1 expression was significantly associated with tumor metastasis (OR 0.37, 95% CI 0.16–0.86, P=0.02 and tumor size >5 cm (OR 0.48, 95% CI 0.26–0.88, P=0.02. In contrast, there was no association between high Notch-1 expression and tumor differentiation, late TNM stage, tumor number, and portal vein invasion of HCC. In conclusion, Notch-1 overexpression might predict poorer survival and more aggressive behavior in patients with HCC. Keywords: hepatocellular carcinoma, Notch-1, prognosis, clinicopathological features, meta-analysis

  19. Gender Determination using Fingertip Features | Wang | Internet ...

    African Journals Online (AJOL)

    Several previous studies have investigated the gender difference of the fingerprint features. However, regarding to the statistical significance of such differences, inconsistent results have been obtained. To resolve this problem and to develop a method for gender determination, this work proposes and tests three fingertip ...

  20. DONG JIE Zhang, LIANG Wang, ZHON

    Indian Academy of Sciences (India)

    User

    Institute of animal husbandry, Heilongjiang Academy of Agricultural Sciences, Harbin 150086, China. Introduction ... Three fragments of the 5' UTR of the pig Foxn1 gene were obtained by PCR amplification. Primer ... The complete CDS of GATA-1 (NC_010461) and Sp1 (NC_010447) were cloned by RT-PCR. The.

  1. A Presuppositional Approach to Conceptual Schemes | Wang ...

    African Journals Online (AJOL)

    ; for they have been focused too much on the truth-conditional notions of meaning/concepts and translation/interpretation in Tarski's style. It is exactly due to such a Quinean interpretation of the notion of conceptual schemes that the very notion ...

  2. Investigation of hemorheological and analgesic properties of Qing ...

    African Journals Online (AJOL)

    headache, dizziness, and brain concussion sequelae [3, 4]. In a study on treatment of 168 patients with brain injury syndrome, it was reported that QNT had significantly higher therapeutic effects and safety than the western medicine OryzanolR [5]. However, the possible mechanisms involved in this therapeutic effect.

  3. Investigation of hemorheological and analgesic properties of Qing ...

    African Journals Online (AJOL)

    Nao tablet (QNT). Methods: Sixty animals were divided into 6 groups (n = 10 for each group): normal, control, positive and 3 QNT-treated groups (QNT-H, QNT-M, QNT-L). Animals in normal and control groups received normal saline orally, while ...

  4. Public Finance in China since the Late Qing Dynasty

    NARCIS (Netherlands)

    B. Krug (Barbara)

    2008-01-01

    textabstractHow is "public finance" organized in China? Is China’s public finance system different from that of other countries? Can we detect features which link today’s system to the past? Public finance refers to more than annual state budgets and constitutional procedures. It includes foreign

  5. Investigation of hemorheological and analgesic properties of Qing ...

    African Journals Online (AJOL)

    Tropical Journal of Pharmaceutical Research June 2017; 16 (6): 1369-1376 .... mice were sacrificed, and gross changes in liver, heart, spleen, lung, kidney, .... Acute toxicity of QNT. There were no obvious gross changes in the normal group. Spontaneous activity of mice decreased initially, but returned to normal after 2 h.

  6. Epigenetic game theory and its application in plants. Comment on: ;Epigenetic game theory: How to compute the epigenetic control of maternal-to-zygotic transition; by Qian Wang et al.

    Science.gov (United States)

    Zhang, Yuan-Ming; Zhang, Yinghao; Guo, Mingyue

    2017-03-01

    Wang's et al. article [1] is the first to integrate game theory (especially evolutionary game theory) with epigenetic modification of zygotic genomes. They described and assessed a modeling framework based on evolutionary game theory to quantify, how sperms and oocytes interact through epigenetic processes, to determine embryo development. They also studied the internal mechanisms for normal embryo development: 1) evolutionary interactions between DNA methylation of the paternal and maternal genomes, and 2) the application of game theory to formulate and quantify how different genes compete or cooperate to regulate embryogenesis through methylation. Although it is not very comprehensive and profound regarding game theory modeling, this article bridges the gap between evolutionary game theory and the epigenetic control of embryo development by powerful ordinary differential equations (ODEs). The epiGame framework includes four aspects: 1) characterizing how epigenetic game theory works by the strategy matrix, in which the pattern and relative magnitude of the methylation effects on embryogenesis, are described by the cooperation and competition mechanisms, 2) quantifying the game that the direction and degree of P-M interactions over embryo development can be explained by the sign and magnitude of interaction parameters in model (2), 3) modeling epigenetic interactions within the morula, especially for two coupled nonlinear ODEs, with explicit functions in model (4), which provide a good fit to the observed data for the two sexes (adjusted R2 = 0.956), and 4) revealing multifactorial interactions in embryogenesis from the coupled ODEs in model (2) to triplet ODEs in model (6). Clearly, this article extends game theory from evolutionary game theory to epigenetic game theory.

  7. Linear sweep voltammetric studies on the supramolecular complex ...

    Indian Academy of Sciences (India)

    Author Affiliations. Wei Sun1 Na Zhao1 Xueliang Niu1 Yan Wang1 Kui Jiao1. Key Laboratory of Eco-Chemical Engineering of Ministry of Education, College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Qingdao 266042, PR China ...

  8. Photocurrent enhancement of d.c. sputtered copper oxide thin films

    Indian Academy of Sciences (India)

    Unknown

    solar energy converting devices, gas sensors (Jiao et al. 2002; Chowdhuri et al 2003; Liu et al 2003; Wang et al ... through a flow controller with fine adjustments. The oxygen content in the residual amount of air in the ... 8⋅5 mbar by raising the rate of argon flow entering into the chamber in this dynamic sputtering process.

  9. Evidence theory and differential evolution based uncertainty ...

    Indian Academy of Sciences (India)

    Author Affiliations. Hesheng Tang1 2 Yu Su2 Jiao Wang2. State Key Laboratory for Disaster Reduction in Civil Engineering, Tongji University, Shanghai 200092, China; Research Institute of Structural Engineering and Disaster Reduction, College of Civil Engineering, Tongji University, Shanghai 200092, China ...

  10. Isolation and open reading frame 5 gene analysis of porcine ...

    African Journals Online (AJOL)

    ARL

    2012-11-08

    Nov 8, 2012 ... Isolation and open reading frame 5 gene analysis of porcine reproductive and respiratory syndrome virus in. Yunnan Province, China. WANG Qing-lu1, ZHANG Shu-guang1, LI Fu-xiang2, BI Bao-liang1, CHAI Jun1,. WANG Sheng-kui1* and ZHANG Yi-fang1*. 1College of Animal Science and Technology, ...

  11. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science. Jun Wang. Articles written in Bulletin of Materials Science. Volume 29 Issue 1 February 2006 pp 73-76 Composites. Influence of Ce0.68Zr0.32O2 solid solution on depositing -alumina washcoat on FeCrAl foils · Mei-Qing Shen Li-Wei Jia Wen-Long Zhou Jun Wang Ying ...

  12. Genomewide identification, classification and analysis of NAC type ...

    Indian Academy of Sciences (India)

    Xiaojian Peng, Yang Zhao, Xiaoming Li, Min Wu, Wenbo Chai, Lei Sheng, Yu Wang, Qing Dong,. Haiyang Jiang and Beijiu Cheng. J. Genet. 94, 377–390. Table 1. Detailed information of NAC proteins in maize. Gene name. Sequence ID. Chromosome. Size (aa). Mass (da). pI. ZmNAC1. GRMZM2G406204_P01. 1. 664.

  13. Journal of Genetics | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Genetic diversity of bitter taste receptor gene family in Sichuan domestic and Tibetan chicken populations · YUAN SU DIYAN LI UMA GAUR YAN WANG NAN WU BINLONG CHEN HONGXIAN XU HUADONG YIN YAODONG HU QING ZHU · More Details Abstract Fulltext PDF. The sense of bitter taste plays a critical role in ...

  14. New compounds of natural resources in 2008

    African Journals Online (AJOL)

    STORAGESEVER

    2009-09-15

    Sep 15, 2009 ... Review. New compounds of natural resources in 2008. Jinhui Wang1, 2*, Qing Peng1 and Guoyu Li2. 1School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang 110016, P.R. China. 2School of Pharmacy ... peptides from marine sponge. In the microbial area, the.

  15. Heterointegration of Dissimilar Materials

    Science.gov (United States)

    2015-07-28

    Philip Ryan, Li-Peng Wang, Michael Bedzyk, David A. Muller, Long-Qing Chen, Jeremy Levy, and Darrell G. Schlom, Science 324 (5925), 367 (2009). [2...Vurgaftman, J. R. Meyer , J. C. Culbertson, and B. R. Bennett, Appl. Phys. Lett. 82 (25), 4411 (2003). [11] B. R. Bennett, R. Magno, J. B. Boos, W

  16. ‘Quadrilateral’ in Philosophy and Bie-modernism (Comments on Aleš Erjavec’s “Zhuyi: From Absence to Bustle? Some Comments on Wang Jianjiang's Article ‘The Bustle and the Absence of Zhuyi’”

    Directory of Open Access Journals (Sweden)

    Wang Jianjiang

    2017-09-01

    Full Text Available Aleš Erjavec proposed the global philosophical quadrilateral, giving Chinese philosophy, aesthetics, and humanities an expectation. However, the realization of this expectation hinges on the question whether Chinese philosophy as well as aesthetics and the humanities can rid themselves of the staggering level of ‘voice’ and develop their ‘speech’. To make ‘speech’, any nation should have its own idea, theory and Zhuyi. How to overcome the embarrassment that ‘quadrilateral’ expectation implies? Time spatialization and four-phase development theories of the Bie-modern, and great leap forward pause theory have provided an answer. The quadrilateral expectation as shown by Aleš Erjavec, is encountering the antagonism between ‘cosmopolitanism’ and ‘nationalism’. The key to resolving this antagonism is ‘my’ original achievement consisting of ‘Chinese traditional philosophy, Western philosophy, Marxism and I (myself’. Bie-modernism is a Zhuyi of self-regulation, self-renewal and self-transcendence and of their practical implementation.   Article received: May 21, 2017; Article accepted: May 24, 2017; Original scholarly paper How to cite this article: Jianjiang, Wang. "‘Quadrilateral’ in Philosophy and Bie-modernism (Comments on Aleš Erjavec’s “Zhuyi: From Absence to Bustle? Some Comments on Wang Jianjiang's Article ‘The Bustle and the Absence of Zhuyi’”." AM Journal of Art and Media Studies 13 (2017: 123-142. doi: 10.25038/am.v0i13.190

  17. Steroids as an adjunct for reducing the incidence of proliferative vitreoretinopathy after rhegmatogenous retinal detachment surgery: a systematic review and meta-analysis

    Directory of Open Access Journals (Sweden)

    Shi H

    2015-03-01

    Full Text Available Hui Shi,1,2* Tao Guo,3* Peng-Cheng Liu,1 Qian-Yi Wang,1 Ya-Ru Du,1,2 Qing-Yu Liu,1 Meng-Mei He,1 Jun-Ling Liu,1 Jing Yu1 1Department of Ophthalmology, Shanghai Tenth People’s Hospital, School of Medicine, Tongji University, Shanghai, 2Department of First Clinical Medical College, Nanjing Medical University, Nanjing, Jiangsu, 3Department of Ophthalmology, Shanghai Third People’s Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, People’s Republic of China *These authors contributed equally to this work Background: This meta-analysis was performed to determine the effectiveness of steroids as an adjunct following rhegmatogenous retinal detachment (RRD surgery. Methods: RRD patients with or without proliferative vitreoretinopathy (PVR were included. The treatment group included patients in whom steroids were used as an adjunct and a control group in which placebo was used. Only randomized controlled trials were included. We searched the main electronic databases and included studies published until July 2014. PVR odds ratio, visual acuity, retinal reattachment rate, and complications were evaluated in three trials. Results: Three randomized controlled trials were included in the meta-analysis. There was no significant difference in the incidence of postoperative PVR between groups (heterogeneity I2=48%, P=0.14. However, the incidence of postoperative PVR was lower in the treatment group (I2=0%, P<0.0001 than in the control group when a PVR grade C study was excluded. There was no statistically significant difference in postoperative visual acuity between the treatment and control groups (odds ratio -0.18; 95% confidence interval -0.38, 0.02; P=0.08. The two groups had similar results for primary/final retinal reattachment and reoperation rate. There was no significant difference in postoperative intraocular pressure. Conclusion: This systematic review demonstrates that steroids may significantly reduce the incidence of

  18. Comprehensive family therapy: an effective approach for cognitive rehabilitation in schizophrenia

    OpenAIRE

    Cai J; Zhu Y; Zhang W.; Wang Y; Zhang C

    2015-01-01

    Jun Cai,1 Yi Zhu,1 Weibo Zhang,1 Yanfeng Wang,1 Chen Zhang2 1Center for Disease Control and Prevention, Shanghai Mental Health Center, 2Schizophrenia Program, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, People’s Republic of China Background: Antipsychotic medication has limited abilities to improve the cognitive impairments that accompany schizophrenia. Adding psychosocial treatment may result in marked improvements in cognitive funct...

  19. Pattern of cerebral hyperperfusion in Alzheimer's disease and amnestic mild cognitive impairment using voxel-based analysis of 3D arterial spin-labeling imaging: initial experience

    OpenAIRE

    Ding, Bei; Ling,Hua Wei; Huang,Juan; Zhang,Huan; Wang,Tao; Yan,Fu Hua; Zhang,Yong

    2014-01-01

    Bei Ding,1 Hua-wei Ling,1 Yong Zhang,2 Juan Huang,1 Huan Zhang,1 Tao Wang,3 Fu Hua Yan11Department of Radiology, Ruijin Hospital, School of Medicine, Shanghai Jiao Tong University, 2Applied Science Laboratory, GE Healthcare, 3Department of Gerontology, Shanghai Mental Health Center, Shanghai, People's Republic of ChinaPurpose: A three-dimensional (3D) continuous pulse arterial spin labeling (ASL) technique was used to investigate cerebral blood flow (CBF) changes in patients with Alzh...

  20. Surface functionalization of HF-treated silicon nanowires

    Indian Academy of Sciences (India)

    Administrator

    Nath M and Parkinson B A 2006 Adv. Mater. 18 1865. 21. Chen C L, Chen D R, Jiao X L and Wang C Q 2006. Chem. Commun. 4632. 22. Shao M W, Shan Y Y, Wong N B and Lee S T 2005. Adv. Funct. Mater. 15 1478. 23. Park I, Li Z Y, Pisano A P and Willianms R S 2007. Nano Lett. 10 3106. 24. Shir D, Liu B Z, Mohammad ...

  1. [A Brief Description on the origin and evolution of the Section on Eyes in Zheng zhi zhun sheng (Standards for Syndrome Identification and Treatment)].

    Science.gov (United States)

    Chen, Liping

    2014-11-01

    Compiled by Wang Kentang, Zheng zhi zhun sheng (Standards for Syndrome Identification and Treatment) has 11 versions falling into 4 classes: (1) The first xylographic version of Wanli reign system, including the first carved version of Renyin year or 30(th) year of Wanli (1602) of the Ming Dynasty, the Japanese Kanbun Dynasty 1670 version of Tongtuo Book Store version, the version of Yimao year or 14(th) year of Kangxi reign (1675) of the Qing Dynasty from the Jintan Yu's Sanctum, the revised version of Jimao year or 38(th) year of Kangxi reign (1699) of the Qing Dynasty from the Jintan Yu's Sanctum, and the version of the 25(th) year of Guangxu reign (1899) of the Qing Dynasty from the Shancheng Sanctum of Western Shu (Sichuan), altogether 4 versions; (2) The system of Xiujing Sanctum, including the version of Guichou year or the 58(th) year of Qianlong reign (1793) of the Qing Dynasty from the Kim's version of Xiujing Sanctum, the version of Renchen year or the 18(th) year of Guangxu reign (1892) of the Qing Dynasty from the revised version of Shijing Sanctum of Guangzhou, the xylographic version of Jiuxueshan Sanctum of the Qing Dynasty, altogether 3 versions; (3) The system of Compendium of Illustrated Books, referring to the printing version of the Renchen year or 18(th) year of Guangxu reign (1892) from the Printing House of Shanghai Compendium of Illustrated Book; (4) The xylographic version of Daiyue Building system, referring to the version of Jisi year or 14th year of Qianlong reign (1749) of the Qing Dynasty from the Daiyue Building; (5) The system of Jiusitang Sanctum xylographic version of the Qing Dynasty from Jiaxing, referring to the said version; (6) The system of lithographic versions: Hongbaozhai of Shanghai in 1912 and Saoyeshan Sanctum of Shanghai in 1935.

  2. Yi zhi xing jiao yi zhe, fangdichan paomo yu fangdichan zhengce: jian lun zhongguo de fangdichan zhengci

    NARCIS (Netherlands)

    Bao, T.; Wang, Y.

    2011-01-01

    Based on the classical De Long et al (1990), we build a model of housing bubbles to analyze the role of market imperfections (noise traders, liquidity constraint, limited liability and weak property rights protections, etc) and their interactions in the formation of housing bubbles. We show that the

  3. New compounds of natural resources in 2008 | Wang | African ...

    African Journals Online (AJOL)

    Natural products have been the most productive source of new compounds. Hundreds of new compounds are in development. Some of them have pharmaceutical activities, particularly as anticancer and anti-infective agents. Until October, there are 1913 new compounds separated from natural sources in 2008.

  4. A comparison of acidic and enzymatic hydrolysis of rutin | Wang ...

    African Journals Online (AJOL)

    Rutin and its hydrolysis products (isoquercitrin and quercetin) are widely used as important materials in food and pharmaceutical industry. In this study, the effects of various acids and enzymes as catalysts on the hydrolysis reaction of rutin were studied. In comparison with acidic and enzymatic catalysis of rutin, the research ...

  5. Page 1 250 Jihua Wang et al evaluations, an interleaved ...

    Indian Academy of Sciences (India)

    ers are updated along the direction of the subgradient. Numerical results show that the ISG . method converges much faster than a subgradient method, though algorithm convergence has not yet been established. 3.3e Interleaved conjugate gradient method: As mentioned earlier, the dual function is concave, piece-wise ...

  6. Proteomic analysis of human oral verrucous carcinoma | Wang ...

    African Journals Online (AJOL)

    Peptide mass fingerprints (PMFs) obtained by the MALDI-TOF analysis were applied to National Center for Biotechnology Information (NCBI), SWISS-PROT and MSDB databases using Mascot software. Then the 2-DE gel imaging showed that 74, 36 and 31 differential protein spots were found between OVC and OSCC, ...

  7. Rice field for the treatment of pond aquaculture effluents | Wang ...

    African Journals Online (AJOL)

    We conducted an experiment to evaluate the efficiency of rice fields in treating pond aquaculture effluent and its responses to different fertilizer treatments. Four treatments was considered in the experiment: no rice planted as the control (CT); rice planted and no fertilizer input (RE); rice planted and a rate of approximately ...

  8. A rare adverse reaction of sorafenib | Wang | Libyan Journal of ...

    African Journals Online (AJOL)

    It is the only drug approved for use in the systematic treatment of primary HCC, and it offers renewed hope for middle- and late-stage liver cancer patients. Conventional use of sorafenib is 400 mg orally, twice daily, until tumor progression or patient death. The following is a report of a serious episode of skin rash in a liver ...

  9. Impact of Convection on Surface Fluxes Observed During LASP/DYNAMO 2011

    Science.gov (United States)

    2014-12-01

    CONVECTION ON SURFACE FLUXES OBSERVED DURING LASP/ DYNAMO 2011 by Matthew S. Cushanick December 2014 Thesis Advisor: Qing Wang Second Reader...December 2014 Master’s Thesis 4. TITLE AND SUBTITLE 5. FUNDING NUMBERS IMPACT OF CONVECTION ON SURFACE FLUXES OBSERVED DURING LASP/ DYNAMO 2011 6...during the Littoral Air-Sea Processes (LASP)/Dynamics of Madden-Julian Oscillation ( DYNAMO ) experiment. The low-level measurements from the WP-30 are

  10. Journal of Genetics | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Genetics. YOU-LIANG ZHENG. Articles written in Journal of Genetics. Volume 92 Issue 1 April 2013 pp 151-154 Research Note. Identification of 40k -secalin genes · Peng-Fei Qi Qing Chen Thérèse Ouellet Cheng-Xing Le Jia Ai Yu-Ming Wei Ji-Rui Wang You-Liang Zheng · More Details Fulltext ...

  11. Toxoplasmosis complicating lung cancer: a case report

    OpenAIRE

    Lu, Nianhong; Liu, Caihong; Wang, Jiangyuan; Ding, Ying; Ai, Qing

    2015-01-01

    Nianhong Lu, Caihong Liu, Jiangyuan Wang, Ying Ding, Qing Ai Department of Clinical Laboratory, The First Hospital of Jilin University, Changchun, People’s Republic of China Abstract: Toxoplasmosis complicating lung cancer has been described only rarely. Here, we report a case of acute Toxoplasma gondii infection in a patient with squamous lung cancer. A 64-year-old woman was admitted to our hospital with a history of cough of 6 months' duration and chest pain of 1 week&...

  12. AHP 40: Review: CHINA FROM EMPIRE TO NATION-STATE

    Directory of Open Access Journals (Sweden)

    Tristan G Brown

    2016-02-01

    Full Text Available Michael Gibbs Hill's excellent translation of the introduction to Wang Hui's four-volume opus, The Rise of Modern Chinese Thought 现代中 国思想的兴起 provides a substantial contribution to scholars of China and intellectual historians by bringing another of Wang Hui's critical works into English (for other such examples, see Wang and Huters 2003 and 2011. The task of translating could not have been easy, as Wang Hui frequently cites works from Chinese antiquity and translated texts from abroad, making Hill's results truly exceptional. The translation is accessible and painstakingly executed, with many important phrases explained for non-specialists alongside transliterated key terms. The Rise of Modern Chinese Thought demonstrates the need for translation work in the fields of area studies by making the important works of non-English speakers available to Anglophone audiences. As Zhang Yongle pointed out in his review on the work in toto, "It can safely be said that nothing comparable to Wang Hui's work has appeared in China since the late Qing-early Republican period" (Zhang 2010:71. Wang Hui, while exploring the links between China and its past through the country's rich intellectual traditions, manages to deftly discuss China in global terms and historical contexts. Hill's helpful introduction contextualizes Wang's writing style in the zeitgeist of the post Tiananmen period from 1990 to 2010. ...

  13. [The research on the edition of Daquanbencao (Complete Collection of Materia Medica)].

    Science.gov (United States)

    Li, Jian; Zhang, Wei; Zhang, Rui-xian

    2009-07-01

    Zhengleibencao (Classified Materia Medica) had been formed into several kinds of edition systems during its dissemination, among which there was the edition system of Daquanbencao (Complete Collection of Materia Medica). Daquanbencao was originally carved in the Jin dynasty, thereafter it was re-carved in the Yuan, Ming and Qing dynasties so as to form a series of editions such as the edition of Zhenyou in the second year of the Jin dynasty; the edition of the Zongwenshuyuan college in Dade renyan year of the Yuan dynasty; the WANG Qiu's carved edition of Shangyitang hall in the Ming dynasty; the carved edition of Jishanshuyuan, the Jishang mountain college in the Ming dynasty, the reprinted edition of PENG Duan-wu in the Ming dynasty, the supplementary edition of YANG Bi-da in the Qing dynasty;, and the carved edition of KE Feng-shi in the Qing dynasty. Among all the editions, Chongkanjingshizhengleidaquanbencao (Reprinted Classified Daquan Materia Medica from Historical Classics) was the representative one. As a representative of the above editions, the carved edition of WANG took the edition of the Zongwenshuyuan college of the Yuan dynasty as the original edition, but the images picture of materia medica adopted from the edition of Zhenghebencao (Materia Medica of the Zhenghe era).

  14. The effects of the insulin resistance index on the virologic response to entecavir in patients with HBeAg-positive chronic hepatitis B and nonalcoholic fatty liver disease

    Directory of Open Access Journals (Sweden)

    Zhu LY

    2016-08-01

    Full Text Available Li-Yao Zhu,1,* Yu-Gang Wang,2,* Li-Qing Wei,3,* Jian Zhou,1 Wei-Jie Dai,4 Xiao-Yu Zhang5,6 1Department of Hepatology, The Fourth People’s Hospital of Huai’an, Huai’an, Jiangsu, 2Department of Gastroenterology, Shanghai Tongren Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 3Department of Medical Laboratory, The Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, 4Department of Gastroenterology, Huai’an First People’s Hospital, Nanjing Medical University, 5Division of Gastrointestinal Surgery, Department of General Surgery, The Affiliated Huai’an Hospital of Xuzhou Medical College, 6Division of Gastrointestinal Surgery, Department of General Surgery, The Second People’s Hospital of Huai’an, Huai’an, Jiangsu, People’s Republic of China *These authors contributed equally to this work Purpose: To further observe and verify the effect of nonalcoholic fatty liver disease (NAFLD on the response to antiviral therapy in patients with chronic hepatitis B (CHB and investigate the relationship between the virologic response and insulin resistance. Patients and methods: A retrospective study was adopted and 61 NAFLD patients with HBeAg-positive CHB were included as the observation group (group A, and 64 patients with simple CHB were included as the control group (group B. Results: After 12 weeks of treatment with entecavir, the total virologic response rate in group A was statistically significantly lower than that in group B (P<0.05. During weeks 24–96, the difference was not statistically significant (P>0.05. In weeks 48 and 96, there was no significant difference in the HBeAg seroconversion rates between the two groups (P>0.05. In weeks 12 and 24, there was also no significant difference in the alanine transaminase (ALT normalization rate between the two groups (P>0.05. Then, in weeks 48 and 96, the ALT normalization rate of group A was obviously

  15. [Thought of charity-persuasion and the compilation, carving and spread of medical formulary in the Qing Dynasty].

    Science.gov (United States)

    Liu, Xiyang

    2015-09-01

    Since the Song Dynasty, morality books aiming at guiding agaisnst evil and persuading charity, spread widely in the civil society. Many medical issues were categorized as encouraging kindness, hence, the thought of encouraging kindness was gradually infiltrated into the development of medical and health services. For the dissemination of medical knowledge, medical formulary became the favorite to well-doers because of its practicability in curing diseases and saving lives. Therefore, the thought of encouraging kindness infiltrated into the compilation, carving and spread of many medical formularies. The thought of encouraging kindness not only rendered a lot of doctors throw their whole life into the cause, but also attracted groups such as Confucian scholars, officers, scholar-officials and many organizations such as benevolent society, benevolent association, bookshop and publishing house to join in, thus increasing the entities of spreaders, expanding the range for the spread of medical knowledge and promoting the popularization and utilization of medical knowledge in grass-root society and remote area, which was helpful in dealing with the social problems such as shortage of medical resources and its uneven distribution.

  16. Arquitectura, geometría y paisaje en la dinastia Qing y el japón Tokugawa

    OpenAIRE

    Ramírez Juidias, Emilio

    2011-01-01

    Desde tiempos lejanos, una de las preocupaciones del hombre en Asia Oriental ha sido conocer el mundo en el q ue se movía y que le rodeaba. En su afán por aprehenderlo surgieron diversas ciencias, tales como la geometría, la arquitectura, el paisajismo y por supuesto, ligado a todas ellas la geomancia. Este interés constante provocó un intercambio de conocimientos entre diferentes dinastías e incluso entre diversas naciones (China, Japón y Coreo principalmente). Sin embargo no podemos dejar d...

  17. Understanding Korean experiences of online game hype, identity, and the menace of the "Wang-tta".

    OpenAIRE

    Chee, Florence

    2005-01-01

    THEME: Internationalism: Worlds at Play The context South Korea continues to set the pace in the world of online games. The nation is a world leader in broadband penetration rates and has a very high level of online game playing. This study reports on the intricate relationship between the sociocultural factors at work in Korean game communities and the context of how games are received. The original field research reported here adds to current knowledge of the interplay between science, tech...

  18. Wang et al., Afr J Tradit Complement Altern Med. (2016) 13(6):121-129

    African Journals Online (AJOL)

    static quenching. The experimental results of synchronous fluorescence and CD spectra showed that the conformation of BSA was changed in the presence of triptolide. Conclusion: It indicated that triptolide could .... Kollman united atom type charges and Essential polar hydrogen atoms were added as well as waters were ...

  19. Analysis of Optical Variations of BL Lac Object AO 0235+164 Wang ...

    Indian Academy of Sciences (India)

    The author would like to thank Dr. Liu Wenpo from Civil Aviation University of. China for a constructive discussion. He acknowledges the archive data from the. Whole Earth Blazar Telescope (WEBT) consortium. This work is supported by the LangFang Municipal Science and Technology Research and Development Pro-.

  20. Optical Spectra Evolution of BL Lac Objects XW Bi1,∗ , BZ Wang2 ...

    Indian Academy of Sciences (India)

    Abstract. Many quasi-simultaneous optical observations of nine BL. Lac objects are obtained from literature. We study the relationship between the optical spectral index and the luminosity of BL Lac objects, and are tempted to exploit spectral evolution in the optical frequency ranges. Our results show that: (i) The optical ...

  1. JPRS Report, China, Wang Meng’s ’Hard Thin Gruel’.

    Science.gov (United States)

    1992-03-26

    vicissitudes. In these times when we are beset from all sides with calls to make self examinations, to recall past griefs and despise old things, when...where the acupuncture needle goes in, this is the nose of the ox where the ring goes, this is the center of the bull’s-eye. Everyone goes up for

  2. Wang et al., Afr J Tradit Complement Altern Med. (2015) 12(5):118 ...

    African Journals Online (AJOL)

    Proff.Adewunmi

    10.4314/ajtcam.v12i5.16. 121 manipulated for 1 minute with an interval of 10 minutes. Resting-state fMRI scan. The fMRI scanning were carried out in a 3.0 Tesla Signa HDxt MRI scanner (GE Company, Fairfield, America) at First Affiliated Hospital.

  3. Wang et al., Afr J Tradit Complement Altern Med. (2013) 10(2):251 ...

    African Journals Online (AJOL)

    AJTCAM

    Perilla frutescens(L.) is a popular herbaceous plant for its pleasant aroma and taste. Its leaves are delicious ... antibodies were goat anti-mouse-HRP and goat anti-rabbit-HRP (IgG; Pierce, 1:3000). Finally, the PVDF ... buffer(pH 6.0). Sections were cooled at room temperature and incubated in rabbit anti-pAkt Ser473 (1:500, ...

  4. Hiina mõistatus : Wang-Ba ja palju muudki / Erkki Bahovski

    Index Scriptorium Estoniae

    Bahovski, Erkki, 1970-

    2008-01-01

    Artikli autor annab ülevaate Euroopa Välissuhete Nõukogu tegevdirektori Mark Leonardi raamatust "What Does China Think?". Raamatu autori väide on lihtne: selleks, et aru saada maailma poliitikast, tuleb aru saada Hiinas toimuvast

  5. Wang et al., Afr J Tradit Complement Altern Med. (2015) 12(5):89-98 ...

    African Journals Online (AJOL)

    Proff.Adewunmi

    The small intestinal transit rate was calculated as the percentage of the distance traveled by the charcoal meal relative to the total length of the small intestine. Fecal Output Character in Normal Mice. Mice (16 male and 16 female) were randomly divided into four groups (n=8 in each group): normal group and three doses of ...

  6. VizieR Online Data Catalog: AO imaging of KOIs with gas giant planets (Wang+, 2015)

    Science.gov (United States)

    Wang, J.; Fischer, D. A.; Horch, E. P.; Xie, J.-W.

    2017-09-01

    From the NASA Exoplanet Archive (http://exoplanetarchive.ipac.caltech.edu), we select Kepler Objects of Interest (KOIs) that satisfy the following criteria: (1) disposition of either Candidate or Confirmed, (2) stellar effective temperature (Teff) lower than 6500 K, (3) stellar surface gravity (log g) higher than 4.0, (4) Kepler magnitude (KP) brighter than 14th mag, (5) with at least one gas giant planet (3.8 R{earth}=

  7. Computational Thermodynamics of Materials Zi-Kui Liu and Yi Wang

    Energy Technology Data Exchange (ETDEWEB)

    Devanathan, Ram

    2017-02-01

    This authoritative volume introduces the reader to computational thermodynamics and the use of this approach to the design of material properties by tailoring the chemical composition. The text covers applications of this approach, introduces the relevant computational codes, and offers exercises at the end of each chapter. The book has nine chapters and two appendices that provide background material on computer codes. Chapter 1 covers the first and second laws of thermodynamics, introduces the spinodal as the limit of stability, and presents the Gibbs-Duhem equation. Chapter 2 focuses on the Gibbs energy function. Starting with a homogeneous system with a single phase, the authors proceed to phases with variable compositions, and polymer blends. The discussion includes the contributions of external electric and magnetic fields to the Gibbs energy. Chapter 3 deals with phase equilibria in heterogeneous systems, the Gibbs phase rule, and phase diagrams. Chapter 4 briefly covers experimental measurements of thermodynamic properties used as input for thermodynamic modeling by Calculation of Phase Diagrams (CALPHAD). Chapter 5 discusses the use of density functional theory to obtain thermochemical data and fill gaps where experimental data is missing. The reader is introduced to the Vienna Ab Initio Simulation Package (VASP) for density functional theory and the YPHON code for phonon calculations. Chapter 6 introduces the modeling of Gibbs energy of phases with the CALPHAD method. Chapter 7 deals with chemical reactions and the Ellingham diagram for metal-oxide systems and presents the calculation of the maximum reaction rate from equilibrium thermodynamics. Chapter 8 is devoted to electrochemical reactions and Pourbaix diagrams with application examples. Chapter 9 concludes this volume with the application of a model of multiple microstates to Ce and Fe3Pt. CALPHAD modeling is briefly discussed in the context of genomics of materials. The book introduces basic thermodynamic concepts clearly and directs readers to appropriate references for advanced concepts and details of software implementation. The list of references is quite comprehensive. The authors make liberal use of diagrams to illustrate key concepts. The two Appendices at the end discuss software requirements and the file structure, and present templates for special quasi-random structures. There is also a link to download pre-compiled binary files of the YPHON code for Linux or Microsoft Windows systems. The exercises at the end of the chapters assume that the reader has access to VASP, which is not freeware. Readers without access to this code can work on a limited number of exercises. However, results from other first principles codes can be organized in the YPHON format as explained in the Appendix. This book will serve as an excellent reference on computational thermodynamics and the exercises provided at the end of each chapter make it valuable as a graduate level textbook. Reviewer: Ram Devanathan is Acting Director of Earth Systems Science Division, Pacific Northwest National Laboratory, USA.

  8. [The author of Yi du (Medicine Reading) and source and history of its editions].

    Science.gov (United States)

    Wan, S M; Lu, X; Wang, X G

    2017-07-28

    Yi du (Medicine Reading)was a primer of traditional Chinese medicine. The original author was Wang Ji of the Ming Dynasty, and the book was block-printed and published, after the supplement made by Cheng Yingmao of the Qing Dynasty during the reign of Kangxi Emperor of the Qing Dynasty. The editions of the book preserved in Nanjing Library and China Institute for History of Medicine and Medical Literature of China Academy of Chinese Medical Sciences was the original version in the reign of Kangxi Emperor. The edition in Shanghai University of Traditional Chinese Medicine was the amended version of original version in the reign of Kangxi Emperor. The version of Edo Period in the Cabinet Library of National Archives of Japan was the reprinted edition of the amended version of original version in the reign of Kangxi Emperor. The transcript of Mr. Wang Shishan's Medicine Reading of the Qing Dynasty in Nanjing Library and Suzhou Library was the hand-copied version of the original one, with 75 syndromes, including external contraction, internal injuries, woman miscellaneous diseases etc. and all sorts of prescriptions. Cheng Yingmao added his preface, 14 syndromes of children diseases and prescription verse, supplemented general notices, properties of materia medica, pulse manifestations, and revised some texts of pathogenesis to form the 7 volumes. The former 5 volumes of Yi du were in 4-character verses, the 6(th)~7(th) volumes were in 7-character verses, and the pill prescriptions were in prose, which made more convenient for beginners to read, remember, and for recitation.

  9. Neuroprotective effects of salidroside through PI3K/Akt pathway activation in Alzheimer’s disease models

    Directory of Open Access Journals (Sweden)

    Zhang B

    2016-04-01

    Full Text Available Bei Zhang,1,2 Ying Wang,1 Hui Li,1 Ran Xiong,1 Zongbo Zhao,1 Xingkun Chu,2 Qiongqiong Li,1 Suya Sun,1 Shengdi Chen1,2 1Department of Neurology, Institute of Neurology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, People’s Republic of China; 2Laboratory of Neurodegenerative Diseases, The Institute of Health Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai Jiao Tong University School of Medicine, Shanghai, People’s Republic of China Abstract: Alzheimer’s disease (AD is a devastating neurodegenerative disorder characterized by deposits of aggregated amyloid-β (Aβ peptide and neurofibrillary tangles in the brain parenchyma. Despite considerable research to elucidate the pathological mechanisms and identify therapeutic strategies for AD, effective treatments are still lacking. In the present study, we found that salidroside (Sal, a phenylpropanoid glycoside isolated from Rhodiola rosea L., can protect against Aβ-induced neurotoxicity in four transgenic Drosophila AD models. Both longevity and locomotor activity were improved in Sal-fed Drosophila. Sal also decreased Aβ levels and Aβ deposition in brain and ameliorated toxicity in Aβ-treated primary neuronal culture. The neuroprotective effect of Sal was associated with upregulated phosphatidylinositide 3-kinase (PI3K/Akt signaling. Our findings identify a compound that may possess potential therapeutic benefits for AD and other forms of neurodegeneration. Keywords: Alzheimer’s disease, amyloid-β, salidroside, Drosophila, neuroprotective effect

  10. Ratcheting of 316L stainless steel thin wire under tension-torsion loading

    Directory of Open Access Journals (Sweden)

    Sichao Fu

    2016-10-01

    Full Text Available A series of cyclic tension-torsion tests under symmetric shear strain and asymmetric axial stress control in various loading paths are conducted on 100 μm-diameter 316L steel wires applying a micro tensiontorsion fatigue testing apparatus. The ratcheting strain of the thin wire increases with increasing axial mean stress and decreases in a sequence of linear, rhombic and circular paths. The macro-scale based cyclic plastic constitutive models with kinematic hardening rules of the Ohno-Wang (OW and the Chen-Jiao-Kim (C-J-K are evaluated for the thin wire. Comparing with the O-W, the C-J-K predicts more accurately under high axial stress. While the loading path effects on ratcheting for wire specimens are basically simulated, the macro-based models tend to under-estimate the effect of phase difference between axial and torsional loadings and the ratcheting evolution in the initial 50 cycles

  11. Silverization of China during the Ming-Qing Transition (ca. 1550-1700) and the Consequences for Research into the Babylonian Economy

    NARCIS (Netherlands)

    van Leeuwen, Bas; XU, Yi; Kleber, Kristin; Pirngruber, Reinhard

    2016-01-01

    In a recent publication, Prof. Van der Spek (2011) made an intriguing comparison between the flows of silver in the Chinese economy at the end of the Ming dynasty and in Babylonia ca. 400-60 BC. He concluded that in China the expansion of the silver economy worked positively for economic growth,

  12. [Textual research on Guang dong xin yu (New Sayings of Guangdong) quoted in Ben cao gang mu shi yi (Supplements to Compendium of Materia Medica].

    Science.gov (United States)

    Zhang, Ruixian; Zhang, Wei; Li, Jian; Liang, Fei

    2014-05-01

    Altogether 15 terms for Guang dong xin yu (New Sayings of Guangdong) were used in Ben cao gang mu shi yi (Supplements to Compendium of Materia Medica), including Yue yu (Cantonese sayings), Chong yu (Sayings from Insect Drug), Jie yu (Sayings from Crustacean Drug), Xin yu (New Sayings), Yue hai xiang yu (Fragrant Sayings from Cantonese Region), Yue zhi mu yu (Sayings from Plants in Cantonese Annals), Guang dong suo yu (Trivial Sayings from Guangdong), Yue shan lu (Records of Cantonese Mountains), Yue lu (Cantonese Records), Jiao guang lu (Joint Guangdong Records), Yue cao zhi (Records of Cantonese Grasses), Guang guo lu (Records of Guangdong Fruits), Nan yue suo ji (Trivial Records of Southern Canton), Guang zhi (Guangdong Records), Yue zhi (Cantonese Records) etc. dealing with 57 sorts of drugs (with individual overlapping ones), the author of Xin yu was Qu Dajun, a surviving fogy of the Ming Dynasty actively involved in the activities to restore the old dynasty and resist the Qing Dynasty, and was persecuted in the literary inquisition in which his works were burnt so that Zhao Xuemin, when quoting his texts, had to go in a roundabout way.

  13. [Origin and development of hemorrhagic stroke].

    Science.gov (United States)

    Zheng, Guo-Qing; Huang, Pei-Xin

    2005-01-01

    Research works were done on origin and development of the denomination, the acute stage of etiopathogenisis and pathogenesis, therapeutical priniciple and therapeutical methods in hemorrhagic stroke. Stroke was divided into is chemic and hemorrhagic until the end of the Qing dynasty. In 1997, Terminology of Traditional Chinese Medicine Treatment-Disease Part of National Standard formally included the term hemorrhagic stroke. Before 1950s-1960s, the pathogenesis emphasizes the up-stirring of liver, the adverse-rising of both blood and qi. A proper remedy should to subdue the liver yang, calm down the endopathic wind and clear heat. Since 1970s, it has been considered that the disorder is closely related with the spleen and stomach. The focal pathogenesis was blocked passage of the middle jiao, disorder of qi in ascending and descending and the abnormal flow of qi and blood. Since 1980s, it was claimed that hemorrhagic stroke belongs to blood syndrome of TCM. The vital pathogenesis was accumulation of blood stasis in acute stage of hemorrhagic stroke. The key point of therapeutical method was to promote blood circulation to remove blood stasis. In recent years, the theories of endogenous toxic factor, consumption, yin and yang syndrome, and the therapeutical method of antidote, assisting the vital qi, especially the development of common therapeutical methods were developed, with an abundance of differential diagnosis and treatment in hemorrhagic stroke.

  14. Criticality of the random-site Ising model: Metropolis, Swendsen-Wang and Wolff Monte Carlo algorithms

    Directory of Open Access Journals (Sweden)

    D.Ivaneyko

    2005-01-01

    Full Text Available We apply numerical simulations to study of the criticality of the 3D Ising model with random site quenched dilution. The emphasis is given to the issues not being discussed in detail before. In particular, we attempt a comparison of different Monte Carlo techniques, discussing regions of their applicability and advantages/disadvantages depending on the aim of a particular simulation set. Moreover, besides evaluation of the critical indices we estimate the universal ratio Γ+/Γ- for the magnetic susceptibility critical amplitudes. Our estimate Γ+/Γ- = 1.67 ± 0.15 is in a good agreement with the recent MC analysis of the random-bond Ising model giving further support that both random-site and random-bond dilutions lead to the same universality class.

  15. Ada (Trade Name) Compiler Validation Summary Report: Alsys Inc., AlsyCOMP 003, V3.1, Wang PC 280.

    Science.gov (United States)

    1988-06-04

    constructs and that i.t identifies and rejects illegal language constructs. The testing also identifies behaviour that is implementation dependent but...test for which the compiler generates a result that demonstrates nonconformity to the Ada Standard. 1-3 % INTRODUCTION Host The computer on which the...INFORMATION 2.2 IMPLEMENTATION CHARACTERISTICS One of the purposes of validating compilers is to determine the behaviour of a compiler in those areas of the

  16. Equivalence of cooperation indexes. Comment on "Universal scaling for the dilemma strength in evolutionary games" by Z. Wang et al.

    Science.gov (United States)

    Martinez-Vaquero, Luis; Grujić, Jelena; Lenaerts, Tom

    2016-03-01

    Symmetric 2 × 2 games where two players can select between two actions and the payoff depends on what they both choose, provide one of the simplest models to study the evolution of cooperation. The actions are usually called cooperation (C) and defection (D) and the payoffs they receive are R (reward for mutual cooperation), P (punishment for mutual defection), T (temptation to defect) and S (suckers payoff). The relative ordering of these 4 payoff values determines the type of dilemma: Prisoner's Dilemma (PD) when T > R > P > S, Snowdrift with T > R > S > P and Stag-Hunt with R > T > P > S. Within the framework of Darwinian Evolution it is well known that in the PD, where both greed (T > R) and fear (P > S) are present, the evolution of cooperation is an important conundrum [1], requiring the identification of mechanisms to overcome it.

  17. VizieR Online Data Catalog: Transiting Exoplanet Monitoring Project. II. HAT-P-33 (Wang+, 2017)

    Science.gov (United States)

    Wang, Y.-H.; Wang, S.; Liu, H.-G.; Hinse, T. C.; Laughlin, G.; Wu, D.-H.; Zhang, X.; Zhou, X.; Wu, Z.; Zhou, J.-L.; Wittenmyer, R. A.; Eastman, J.; Zhang, H.; Hori, Y.; Narita, N.; Chen, Y.; Ma, J.; Peng, X.; Zhang, T.-M.; Zou, H.; Nie, J.-D.; Zhou, Z.-M.

    2017-10-01

    We have recorded a total of 10 light curves of eight different transits events observed by two telescopes (a 60/90cm Schmidt and a 60cm telescope) at Xinglong Station operated by National Astronomical Observatories of China (NAOC) between 2013 December and 2016 January. Two of the transit events were observed by the two telescopes simultaneously. The first seven transit events were monitored by the 60/90cm Schmidt telescope. It has a 4K*4K CCD with a ~94'*~94' field of view, which gives a pixel scale of 1.38''/pixel. The transit events that occurred on UT 2014 February 27 and UT 2014 March 6 were also simultaneously observed by the 60cm, and the last transit in our sequence was also monitored with this telescope. The 60cm telescope is equipped with a 512*512 CCD and covers a field of view of 17'*17', resulting in a pixel scale of 1.95''/pixel. (3 data files).

  18. 一般論述/Information Science: The Territory and Relations to Computing Disciplines/Bing Wang

    Directory of Open Access Journals (Sweden)

    Bing Wang Bing Wang

    2009-04-01

    Full Text Available The nature of information science (IS as a discipline has been a matter of dispute almost since the day it was created. What is less controversial is the interdisciplinary nature of the IS field, which has close relationships with such fields as librarianship/library science, computing disciplines, communication, and cognitive science. Since 1990s, with the rapid development and widespread application of computing and information technologies, especially the Internet and WWW, the nature, territory and education of the IS field has been constantly changing, and is increasingly tied to Internet-based technologies and connected to knowledge management and data mining. The relationships between IS and computing disciplines are becoming more complicated than ever. In this paper the similarities and differences between IS, computer science, information systems, and information technology field are examined in terms of their definitions, major research topics, primary foci, practice areas for professionals, and educations. The purpose of this paper is to provide some insights into the essence and roles of IS in contemporary academic community.頁次:4-22

  19. VizieR Online Data Catalog: NGC 104, 6121 & 6809 AGB and RGB stars Na abundance (Wang+, 2017)

    Science.gov (United States)

    Wang, Y.; Primas, F.; Charbonnel, C.; van der Swaelmen, M.; Bono, G.; Chantereau, W.; Zhao, G.

    2017-09-01

    The spectra of our sample of AGB and RGB stars in the Galactic globular clusters NGC 104, NGC 6121 and NGC 6809 were obtained with the high-resolution multi-object spectrograph FLAMES, mounted on ESO/VLT-UT2, taking advantage of GIRAFFE for the majority of our sample stars and used the UVES fibres for the brightest objects of each cluster. The basic information of our sample stars are listed in Table 3, including the evolutionary phase, instrument used for observation, coordinates, photometry and barycentric radial velocity. Our Fe abundances were derived from the equivalent widths of Fe lines, while the Na abundances were determined with spectra synthesis. Both FeI and Na abundances have been corrected for the non-LTE effect. In Table 5 we show the derived stellar parameters of our sample stars, and the Na abundances are shown in Table 7. (3 data files).

  20. Hongzhan LIU 1,2, Gaisheng ZHANG 1,*, Junsheng WANG 2, Qingsong BA 1, Huixue CHE 1, Yulong

    OpenAIRE

    Liu, Hongzhan; Zhang, Gaisheng; Wang, Junsheng; BA, Qingsong; CHE, Huixue; Song, Yulong; Zhang, Pengfei; Niu, Na; Wang, Junwei; MA, Shoucai; Chen, Long

    2015-01-01

    Malondialdehyde (MDA), which is thought to be important inducible factor of cell apoptosis if excessively accumulated in cells, is often regarded as a widely used marker of oxidative lipid injury whose concentration varies in response to biotic and abiotic stress. To elucidate the metabolic mechanism of ROS production and scavenging of the male sterility, normal fertility and male sterility wheat, including genetic and physiologically male sterility, by comparing MDA content and antioxidant e...

  1. VizieR Online Data Catalog: Energy levels & transition rates of O-like ions (Wang+, 2017)

    Science.gov (United States)

    Wang, K.; Jonsson, P.; Ekman, J.; Gaigalas, G.; Godefroid, M. R.; Si, R.; Chen, Z. B.; Li, S.; Chen, C. Y.; Yan, J.

    2017-06-01

    Employing two state-of-the-art methods, multiconfiguration Dirac-Hartree-Fock and second-order many-body perturbation theory, the excitation energies and lifetimes for the lowest 200 states of the 2s22p4, 2s2p5, 2p6, 2s22p33s, 2s22p33p, 2s22p33d, 2s2p43s, 2s2p43p, and 2s2p43d configurations, and multipole (electric dipole (E1), magnetic dipole (M1), and electric quadrupole (E2)) transition rates, line strengths, and oscillator strengths among these states are calculated for each O-like ion, from CrXVII to ZnXXIII. Our two data sets are compared with the National Institute of Standards and Technology and CHIANTI compiled values, and previous calculations. The data are accurate enough for identification and deblending of new emission lines from the Sun and other astrophysical sources. The amount of high-accuracy data is significantly increased for the n=3 states of several O-like ions of astrophysical interest, where experimental data are very scarce. (3 data files).

  2. [Investigation on the number of ancient medical books collected in Haiyuan Private Library].

    Science.gov (United States)

    Man, Xue; Liu, Gengsheng

    2015-03-01

    Yang's Haiyuan Private Library in Liaocheng City, Shandong Province, is the only extant one among the four famous private libraries of the Qing dynasty in Northern China. Its collection is ample and graceful and especially rich in rare and secret versions, amounting to over 2 000 kinds, 200- thousand volumes. By sorting out 5 kinds of such collections from the Yang's family catalogue of Liaocheng in Shandong, plus 3 kinds of supplemented catalogue by Wang Shaozeng, the Catalogue of Haiyuan Private Library Collected in Shandong Provincial Library, and catalogues of modern scholars, it can be basically identified that the number of medical collections of Yang's Haiyuan Private Library is 87 kinds. Supposing all kinds contain 112 works, then Haiyuan Private Library totally has 1296 volumes according to the catalogues.

  3. Development of acquired factor V inhibitor after treatment with ceftazidime: a case report and review of the literature

    Directory of Open Access Journals (Sweden)

    Cui QY

    2015-04-01

    Full Text Available Qing-ya Cui,1 Hong-shi Shen,1 Tian-qin Wu,1 Hai-fei Chen,1 Zi-qiang Yu,2 Zhao-yue Wang2 1Department of Hematology, PLA 100th Hospital, 2Jiangsu Institute of Hematology, The First Affiliated Hospital of Soochow University, Suzhou, People’s Republic of China Abstract: We report the case of a 59-year-old Chinese man who showed an asymptomatic coagulation factor V deficiency pattern after second intravenous treatment with ceftazidime. Normal pooled plasma failed to correct the abnormalities in a mixing test, and the presence of factor V inhibitor was confirmed by the Bethesda method. The coagulopathy was not corrected by transfusion of fresh frozen plasma and prothrombin complex concentrate, but rather by treatment with prednisone and withdrawal of dubious drugs. The findings reported here should prompt clinicians to watch for drug-induced coagulation factor deficiency. Keywords: acquired factor V deficiency, coagulopathy, prednisone

  4. Hepatocyte-targeting gene transfer mediated by galactosylated poly(ethylene glycol- graft-polyethylenimine derivative

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    Wang YQ

    2013-03-01

    Full Text Available Yuqiang Wang,1,* Jing Su,2,* Wenwei Cai,3 Ping Lu,3 Lifen Yuan,3 Tuo Jin,2 Shuyan Chen,1 Jing Sheng3 1Department of Geriatrics, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, People’s Republic of China; 2School of Pharmacy, Shanghai Jiao Tong University, Shanghai, People’s Republic of China; 3Department of Geriatrics, Shanghai Ninth People’s Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, People’s Republic of China *Both authors contributed equally to this work Abstract: Biscarbamate cross-linked polyethylenimine derivative (PEI-Et has been reported as a novel nonviral vector for efficient and safe gene transfer in our previous work. However, it had no cell-specificity. To achieve specific delivery of genes to hepatocytes, galactosylated poly(ethylene glycol-graft-polyethylenimine derivative (GPE was prepared through modification of PEI-Et with poly(ethylene glycol and lactobionic acid, bearing a galactose group as a hepatocyte-targeting moiety. The composition of GPE was characterized by proton nuclear magnetic resonance. The weight-average molecular weight of GPE measured with a gel permeation chromatography instrument was 9489 Da, with a polydispersity of 1.44. GPE could effectively condense plasmid DNA (pDNA into nanoparticles. Gel retardation assay showed that GPE/pDNA complexes were completely formed at weigh ratios (w/w over 3. The particle size of GPE/pDNA complexes was 79–100 nm and zeta potential was 6–15 mV, values which were appropriate for cellular uptake. The morphology of GPE/pDNA complexes under atomic force microscopy appeared spherical and uniform in size, with diameters of 53–65 nm. GPE displayed much higher transfection efficiency than commercially available PEI 25 kDa in BRL-3A cell lines. Importantly, GPE showed good hepatocyte specificity. Also, the polymer exhibited significantly lower cytotoxicity compared to PEI 25 kDa at the

  5. Research progress on criteria for discontinuation of EGFR inhibitor therapy

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    Zhuang HQ

    2012-10-01

    Full Text Available Hong-qing Zhuang, Zhi-yong Yuan, Jun Wang, Ping Wang, Lu-jun Zhao, Bai-lin ZhangDepartment of Radiotherapy, Tianjin Medical University Cancer Institute and Hospital, Tianjin Key Laboratory of Cancer Prevention and Therapy, Tianjin Lung Cancer Center, Tianjin, People's Republic of ChinaAbstract: The clinical success of the epidermal growth factor receptor (EGFR tyrosine kinase inhibitors (TKI as therapeutic agents has prompted great interest in their further development and clinical testing for a wide variety of malignancies. However, most studies have focused on the efficacy of TKI, and few studies have been done on the criteria for their discontinuation. The current standard for drug discontinuation is “until progression”, based on change in tumor size. However, tumor size is not related to the gene expression which determines the efficacy of TKI in the final analysis, and it is also difficult to make a thorough and correct prediction based on tumor size when the TKI is discontinued. Nevertheless, clinical evaluation of the criteria for TKI discontinuation is still in its early days. Some promising findings have started to emerge. With the improving knowledge of EGFR and its inhibitors, it is expected that the criteria for discontinuation of EGFR inhibitor therapy will become clearer.Keywords: epidermal growth factor receptor, drug discontinuation, acquired drug-resistance

  6. The 2nd International Conference on Agricultural and Biological Sciences (ABS 2016

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    Lei Pei

    2016-10-01

    Full Text Available Table of contents 01 The influence of soil salt content on the photosynthetic characteristics of spring wheat with trickle irrigation Lei Pei, Zhenhua Wang, Jinzhu Zhang, Wenhao Li 02 Comparing growth of fast-growing and slow-growing endophytes in plants via ergosterol quantification Adeline SY Ting, Yiing Y Chow, Sadequr Rahman 03 Transcriptome and digital gene expression analysis identifies putative triterpene saponin-biosynthetic genes of Panax notoginseng Rongchang Wei 04 Chitosan-assisted isolation and antioxidant evaluation of flavonoids from Sophora japonica L. Zhang Hu, Sidong Li, Chuyan Li, Zijuan Li 05 Two kinds of new characteristics of the ektexine ornamentation of ginkgo pollen Guoxia Wang, Yuzhen Yang, Gang Chen, Qing Luo 06 Analysis of nutrient and medicinal ingredients of Ginkgo pollen in different regions Guoxia Wang, Ruixia Liu, Yuzhen Yang, Lipei Chen 07 Photosynthetic performance of greening seedlings of seven species to drought stress Zhiyang Lie, Tongtong Zhou, Weilong Huang, Li Xue 08 Changes of fluorescence parameters of greening seedlings of seven species under drought stress Jie Li, Zhuomin Wang, Li Xue 09 Mammalian sex hormone affects regeneration capacity and enzymes activity of Triticale L in vitro culture Ismail Bezirganoglu, Pınar Uysal 10 Fractional Fourier entropy increases the recognition rate of fruit type detection Shuihua Wang, Zhihai Lu, Jiquan Yang, Yudong Zhang, John Liu, Ling Wei, Shufang Chen, Preetha Phillips, Zhengchao Dong 11 Banana-peanut intercropping reduces Fusarium wilt disease in banana from enhancing soil bacterial microorganisms and leaf nutrition Hong Li, Xutong Wang, Fengliang Zhao, Guisheng Yang 12 Manganese stress impairs stem ureide nitrogen fixation in yardlong-bean plants in the acidic environment Hong Li 13 A new pest control method for Rhytidodera bowringii Larvae Haijie Huang, Li Zhao, Weijian Huang, Jinhui Wang, Zhongrun Zhang 14 Research on the seed-like Fruits of Subg. Sclarea of

  7. IGF2BP3 as a potential tissue marker for the diagnosis of esophageal high-grade intraepithelial neoplasia

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    Zhang JJ

    2017-08-01

    Full Text Available Jingjing Zhang,1,* Qing Ji,2,* Chunhua Jiao,3,* Lihua Ren,4 Ye Zhao,4 Yanfang Chen,4 Ruihua Shi,4 Yadong Feng4 1State Key Laboratory of Reproductive Medicine, Department of Prenatal Diagnosis, Obstetrics and Gynecology Hospital Affiliated to Nanjing Medical University, Nanjing, 2Department of Emergency, Jingjiang People’s Hospital, Jingjiang, 3Department of Gastroenterology, First Affiliated Hospital with Nanjing Medical University, 4Department of Gastroenterology, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, People’s Republic of China *These authors contributed equally to this work Background: The clinical significance of insulin-like growth factor-II mRNA-binding protein-3 (IGF2BP3 in esophageal high-grade intraepithelial neoplasia (HGIN is not clear. This study was designed to characterize the expression of IGF2BP3 in HGIN. Patients and methods: IGF2BP3 expression was evaluated by Western blot analyses in 12 cases and by immunohistochemistry (IHC in 112 cases. The associations between IGF2BP3 expression in HGIN and the clinicopathological parameters were examined. Results: Moderate to strong IGF2BP3 expression was present in HGIN samples. Using IHC, it was found that IGF2BP3 was positive in 68 (60.71% cases. Intense IHC of IGF2BP3 in HGIN was associated with a deeper lesion depth, and the lesion depth was the only predictor of the positive expression of IGF2BP3. Conclusion: Our results suggested that IGF2BP3 may be a supplementary tissue marker for preoperative diagnosis of HGIN. Keywords: esophageal squamous cell carcinoma, precancerous lesion, immunohistochemistry detection, early diagnosis

  8. Treadmill exercise promotes neuroprotection against cerebral ischemia–reperfusion injury via downregulation of pro-inflammatory mediators

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    Zhang Y

    2016-12-01

    Full Text Available Ying Zhang,1,* Richard Y Cao,2,* Xinling Jia,3,* Qing Li,1 Lei Qiao,1 Guofeng Yan,4 Jian Yang1 1Department of Rehabilitation, 2Laboratory of Immunology, Shanghai Xuhui Central Hospital, Shanghai Clinical Research Center, Chinese Academy of Sciences, 3School of Life sciences, Shanghai University, 4School of Medicine, Shanghai Jiao Tong University, Shanghai, People’s Republic of China *These authors contributed equally to this work Background: Stroke is one of the major causes of morbidity and mortality worldwide, which is associated with serious physical deficits that affect daily living and quality of life and produces immense public health and economic burdens. Both clinical and experimental data suggest that early physical training after ischemic brain injury may reduce the extent of motor dysfunction. However, the exact mechanisms have not been fully elucidated. The aim of this study was to investigate the effects of aerobic exercise on neuroprotection and understand the underlying mechanisms.Materials and methods: Middle cerebral artery occlusion (MCAO was conducted to establish a rat model of cerebral ischemia–reperfusion injury to mimic ischemic stroke. Experimental animals were divided into the following three groups: sham (n=34, MCAO (n=39, and MCAO plus treadmill exercise (n=28. The effects of aerobic exercise intervention on ischemic brain injury were evaluated using functional scoring, histological analysis, and Bio-Plex Protein Assays.Results: Early aerobic exercise intervention was found to improve motor function, prevent death of neuronal cells, and suppress the activation of microglial cells and astrocytes. Furthermore, it was observed that aerobic exercise downregulated the expression of the cytokine interleukin-1β and the chemokine monocyte chemotactic protein-1 after transient MCAO in experimental rats.Conclusion: This study demonstrates that treadmill exercise rehabilitation promotes neuroprotection against cerebral

  9. Next-generation sequence detects ARAP3 as a novel oncogene in papillary thyroid carcinoma

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    Wang QX

    2016-11-01

    Full Text Available Qing-Xuan Wang, En-Dong Chen, Ye-Feng Cai, Yi-Li Zhou, Zhou-Ci Zheng, Ying-Hao Wang, Yi-Xiang Jin, Wen-Xu Jin, Xiao-Hua Zhang, Ou-Chen Wang Department of Oncology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang Province, China Purpose: Thyroid cancer is the most frequent malignancies of the endocrine system, and it has became the fastest growing type of cancer worldwide. Much still remains unknown about the molecular mechanisms of thyroid cancer. Studies have found that some certain relationship between ARAP3 and human cancer. However, the role of ARAP3 in thyroid cancer has not been well explained. This study aimed to investigate the role of ARAP3 gene in papillary thyroid carcinoma. Methods: Whole exon sequence and whole genome sequence of primary papillary thyroid carcinoma (PTC samples and matched adjacent normal thyroid tissue samples were performed and then bioinformatics analysis was carried out. PTC cell lines (TPC1, BCPAP, and KTC-1 with transfection of small interfering RNA were used to investigate the functions of ARAP3 gene, including cell proliferation assay, colony formation assay, migration assay, and invasion assay. Results: Using next-generation sequence and bioinformatics analysis, we found ARAP3 genes may play an important role in thyroid cancer. Downregulation of ARAP3 significantly suppressed PTC cell lines (TPC1, BCPAP, and KTC-1, cell proliferation, colony formation, migration, and invasion. Conclusion: This study indicated that ARAP3 genes have important biological implications and may act as a potentially drugable target in PTC. Keywords: papillary thyroid carcinoma, next-generation sequence, ARAP3, oncogene

  10. Apuntes sobre las nuevas dinámicas de la Oralidad: Escuchando a "Wang-Fo" en el lenguaje hiper-vincular

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    Alexander Díaz

    2008-01-01

    Full Text Available El presente escrito es una reflexión-narración de cómo la oralidad puede hallarse en estado implícito en las comunidades inmersas en la sociedad mediática de consumo. En este mestizaje semiótico de la tradición, la "Cuenteria" alcanza un valor excepcional en Colombia. Existe la evidencia que en las últimas dos décadas, hombres y mujeres de diversos estratos socioeconómicos y niveles de formación académica diferentes, se reúnen a participar de la cultura oral renovada, un paso delante de los medios masivos; tal portento es una alternativa real y viable para la Oralidad.

  11. 圖書館事業與交流/What Cloud Computing Means to Libraries and Information Services/Xiaocan (Lucy Wang, Jie Huang

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    Xiaocan (Lucy Wang, Jie Huang Xiaocan (Lucy Wang, Jie Huang

    2011-10-01

    Full Text Available Cloud computing, as an emerging style of computing that involves various technologies and provides virtual and scalable IT-related services over the Internet, has become a popular topic in the past few years. Much has been written about this concept and its applications in the IT and business fields, but little has been done in the library setting. This paper first introduces cloud computing with respect to its concepts, types, and general applications. The focus is then shifted to what cloud computing might mean to libraries and information services. The impact of cloud computing on the storage of libraries’ digital assets, integrated library systems, libraries’ IT infrastructures, as well as library services and internal work, has been investigated. The paper also explores the potential benefits of incorporating cloud computing in the library environment and points out some concerns and challenges libraries may have. 雲端計算作為一種新興的、利用多元技術來提供基於網路的IT 服務計算模式,在近幾年來已成為熱門話題。許多文章論述了有關雲端計算的概念及其在IT 和商業中的應用模式,但卻少見對其在圖書館領域中運用的闡述。本文首先介紹有關雲端計算的概念、類型,以及一些基本的應用模式。隨後,本文著眼於雲端計算對圖書館和資訊服務的意義,探討雲端計算在圖書館數位資源儲存、整合圖書館系統、圖書館資訊科技的設施建設、圖書館服務和內部作業等方面產生的影響以及圖書館運用雲端計算的潛在效益。本文剖析圖書館採用雲端計算的益處之時,也同時探討可能面臨的一些問題和挑戰。 頁次:166-174

  12. Connecting human behavior and infectious disease spreading. Comment on "Coupled disease-behavior dynamics on complex networks: A review" by Wang et al.

    Science.gov (United States)

    Holme, Petter

    2015-12-01

    Vaccination against measles is one of the great success stories of 20th century medicine. In the USA, before the introduction of the vaccine in 1963, three to four million adolescents were infected annually, around 500 died, around 5000 got serious complications (primarily encephalitis, swelling of the brain), and around 50,000 were hospitalized [7]. With the vaccine, measles virtually vanished and by 2000 it was declared extinct from the USA. This was, however, not the end of the story. There is still a small fraction of parents who do not let their children be vaccinated. The reasons vary-fear of side effects, an aversion of exposing children to something ;unnatural;, and a large number of other ideas. (For a non-academic account of the psychology of vaccination, we recommend Eula Biss's On Immunity[3].) The last few decades, anti-vaccination ideas have been spreading in social media and united people opposing vaccination into something of a movement [4]. In December 2014 there was a first larger outbreak (over 500 cases) of the century, centered around Disneyland (Anaheim, California) [10], and the anti-vaccination movement got much of the blame [4]. This example illustrates how ideas and opinions-that just like diseases are spreading over networks of people-can facilitate outbreaks. The reverse is, thankfully, more common-people, aware of an emerging outbreak, try to lower the chance of contagion by improving hygiene etc., which impedes the outbreak.

  13. Complex free-energy landscapes in biaxial nematic liquid crystals and the role of repulsive interactions: A Wang-Landau study

    Science.gov (United States)

    Kamala Latha, B.; Murthy, K. P. N.; Sastry, V. S. S.

    2017-09-01

    General quadratic Hamiltonian models, describing the interaction between liquid-crystal molecules (typically with D2 h symmetry), take into account couplings between their uniaxial and biaxial tensors. While the attractive contributions arising from interactions between similar tensors of the participating molecules provide for eventual condensation of the respective orders at suitably low temperatures, the role of cross coupling between unlike tensors is not fully appreciated. Our recent study with an advanced Monte Carlo technique (entropic sampling) showed clearly the increasing relevance of this cross term in determining the phase diagram (contravening in some regions of model parameter space), the predictions of mean-field theory, and standard Monte Carlo simulation results. In this context, we investigated the phase diagrams and the nature of the phases therein on two trajectories in the parameter space: one is a line in the interior region of biaxial stability believed to be representative of the real systems, and the second is the extensively investigated parabolic path resulting from the London dispersion approximation. In both cases, we find the destabilizing effect of increased cross-coupling interactions, which invariably result in the formation of local biaxial organizations inhomogeneously distributed. This manifests as a small, but unmistakable, contribution of biaxial order in the uniaxial phase. The free-energy profiles computed in the present study as a function of the two dominant order parameters indicate complex landscapes. On the one hand, these profiles account for the unusual thermal behavior of the biaxial order parameter under significant destabilizing influence from the cross terms. On the other, they also allude to the possibility that in real systems, these complexities might indeed be inhibiting the formation of a low-temperature biaxial order itself—perhaps reflecting the difficulties in their ready realization in the laboratory.

  14. 圖書館事業與交流/Information-Seeking Behavior of Science Faculty under a Challenging Economic Environment/Jiannan Wang

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    Jiannan Wang Jiannan Wang

    2010-10-01

    Full Text Available The history of the Yongle Dadian’s[1] creation, near total destruction, its wanton dispersal, its promising reprinting and possible digitization, is but one example of a fascinating cultural treasure worth studying. As this paper will show, even the partial recovery of an artifact brings to light the significant contribution of a culture, a time, and a people. The author will trace the course of the Yonele Dadian over 600 years. From the original compilation during the fif-teenth century Ming Dynasty to the burning and looting of the prestigious Hanlin Academy where it was held during the 1900 Siege of Peking. The function and rising importance of the Hanlin Academy as a cultural repository of Chinese scholarship will be discussed. In addition, relying on siege diaries and other primary source materials, the author will present what occurred on that fateful day of June 23, 1900 when the Hanlin Academy was reduced to ashes and its contents looted. Lastly, the author will conclude with the recent reclamation efforts of the Yongle Dadian and touch upon the role of libraries as repositories of intellectual heritage and cultural record. 永樂大典的編作起源幾近毀壞,肆意分散的歷史,以及翻印與數位化的可能性,使它成為值得研究的文化寶藏。誠如本文之呈現,即使是部分古籍的修復,也能對文化、時代以及民族作出重要貢獻。作者將追溯永樂大典六百多年的歷史,從十五世紀明朝時原典的編纂,到西元1900年間,北京被圍攻時,永樂大典的貯藏地「翰林書院」被焚燒以及劫掠。本文也將討論翰林書院作為貯藏中國學術成就的功用和重要性。此外,根據北京圍攻的紀錄和其他文獻,作者也將陳述西元1900年6月23日當天翰林書院被焚燒與劫掠的過程。結論中,將討論近來為收復永樂大典所做的努力,以及探討圖書館在貯藏人文遺產和古蹟的角色。 “It is (as difficult as sieving the sand for gold, or scouting the sea for dia-monds.” Yongle Emperor Zhu Di (in preface to Yongle Dadian, 1408. 頁次:82-91

  15. Cytotoxicity enhancement in MDA-MB-231 cells by the combination treatment of tetrahydropalmatine and berberine derived from Corydalis yanhusuo W. T. Wang

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    Yan Zhao

    2014-04-01

    Conclusion: Our findings suggested that the combination of THP and Ber might be beneficial for anti-proliferation of MDA-MB-231 breast cancer cells through a significant synergy effect. [J Intercult Ethnopharmacol 2014; 3(2.000: 68-72

  16. Reply to comment by J.T. Wang and F. Williams on the stability of alkyl halide and related σ * anions

    Science.gov (United States)

    Symons, ]Martyn C. R.

    1980-06-01

    Conditions under which σ * anions (R .-hal) - are likely to be stable with respect to dissociation into R . + hal - are discussed. It is pointed out that if dissociation leads to ? + hal ., then an important factor is the shape of ? rather than that of R ..

  17. The importance of accurately modelling human interactions. Comment on "Coupled disease-behavior dynamics on complex networks: A review" by Z. Wang et al.

    Science.gov (United States)

    Rosati, Dora P.; Molina, Chai; Earn, David J. D.

    2015-12-01

    Human behaviour and disease dynamics can greatly influence each other. In particular, people often engage in self-protective behaviours that affect epidemic patterns (e.g., vaccination, use of barrier precautions, isolation, etc.). Self-protective measures usually have a mitigating effect on an epidemic [16], but can in principle have negative impacts at the population level [12,15,18]. The structure of underlying social and biological contact networks can significantly influence the specific ways in which population-level effects are manifested. Using a different contact network in a disease dynamics model-keeping all else equal-can yield very different epidemic patterns. For example, it has been shown that when individuals imitate their neighbours' vaccination decisions with some probability, this can lead to herd immunity in some networks [9], yet for other networks it can preserve clusters of susceptible individuals that can drive further outbreaks of infectious disease [12].

  18. When did Wang Shoudao Become the Leader of Northwest Security Bureau?%王首道何时任西北保卫局局长一职?

    Institute of Scientific and Technical Information of China (English)

    李亮

    2011-01-01

    据中记载,王首道被任命为西北保卫局局长一职的时间为中共中央到达瓦窑堡后的1935年11月10日,此一记载有误,王首道被任命为西北保卫局局长一职的时间应在1935年11月3日.

  19. SHORT COMMUNICATION SPECTROPHOTOMETRIC ...

    African Journals Online (AJOL)

    SPECTROPHOTOMETRIC DETERMINATION OF TRACE OXALIC ACID WITH. ZIRCONIUM(IV)-DIBROMOCHLOROARSENAZO COMPLEX. Qing-Zhou Zhai*, Xiao-Xia Zhang and Qing-Zhou Liu. Research Center for Nanotechnology, Changchun University of Science and Technology,. Weixing Road, Changchun 130022, ...

  20. Syndrome Differentiation and Treatment of Dysmenorrhea in Fu QingZhu's Obstetrics and Gynecology%《傅青主女科》痛经病辨证论治规律探析

    Institute of Scientific and Technical Information of China (English)

    张立环

    2016-01-01

    傅青主根据痛经症状及月经先后关系,将痛经分为经水忽来忽断时疼时止、经水未来腹先疼、行经后少腹疼痛、经前腹痛吐血、经水将来脐下先疼痛.治疗上注重肝在月经调节中的作用,兼顾脾肾,其用药平和,多入肝、脾、肾经,不主张峻补峻泻.%Fu Qingzhu classified dysmenorrheal into the types: irregular menstruation and the pain came on and off, abdominal pain before the menstruation came, abdominal pain after the menstruation came, abdominal painand spiting blood before the menstruation came, pain under the navel when the menstruation came according to the symptoms of dysmenorrhea and the relationship between the menstruation and dysmenorrhea. He emphasized the roles of the liver played in regulating menstruation, and gave consideration to spleen and kidney; he believed that the therapy should not be reinforce and reduce suddenly, the properties of the herbs used in the therapies were mild, of liver, spleen and kidney meridians.

  1. Integrating subpathway analysis to identify candidate agents for hepatocellular carcinoma

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    Wang J

    2016-03-01

    Full Text Available Jiye Wang,1 Mi Li,2 Yun Wang,3 Xiaoping Liu4 1The Criminal Science and Technology Department, Zhejiang Police College, Hangzhou, Zhejiang Province, 2Department of Nursing, Shandong College of Traditional Chinese Medicine College, Yantai, Shandong Province, 3Office Department of Gastroenterology, The First Affiliated Hospital of Xi’an Jiao Tong University, Xi’an, Shanxi Province, 4Key Laboratory of Systems Biology, Shanghai Institutes for Biological Sciences, Shanghai, People’s Republic of China Abstract: Hepatocellular carcinoma (HCC is the second most common cause of cancer-associated death worldwide, characterized by a high invasiveness and resistance to normal anticancer treatments. The need to develop new therapeutic agents for HCC is urgent. Here, we developed a bioinformatics method to identify potential novel drugs for HCC by integrating HCC-related and drug-affected subpathways. By using the RNA-seq data from the TCGA (The Cancer Genome Atlas database, we first identified 1,763 differentially expressed genes between HCC and normal samples. Next, we identified 104 significant HCC-related subpathways. We also identified the subpathways associated with small molecular drugs in the CMap database. Finally, by integrating HCC-related and drug-affected subpathways, we identified 40 novel small molecular drugs capable of targeting these HCC-involved subpathways. In addition to previously reported agents (ie, calmidazolium, our method also identified potentially novel agents for targeting HCC. We experimentally verified that one of these novel agents, prenylamine, induced HCC cell apoptosis using 3-(4,5-dimethylthiazol-2-yl-2,5-diphenyltetrazolium bromide, an acridine orange/ethidium bromide stain, and electron microscopy. In addition, we found that prenylamine not only affected several classic apoptosis-related proteins, including Bax, Bcl-2, and cytochrome c, but also increased caspase-3 activity. These candidate small molecular drugs

  2. Mechanism and therapeutic effectiveness of nerve growth factor in osteoarthritis pain

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    Shang X

    2017-08-01

    Full Text Available Xiushuai Shang, Zhaofei Wang, Hairong Tao Department of Orthopedic Surgery, Shanghai Key Laboratory of Orthopedic Implant, Shanghai Ninth People’s Hospital, Shanghai JiaoTong University School of Medicine, Shanghai, China Abstract: Osteoarthritis (OA is the most common form of articular joint arthritis and a cause of significant morbidity. In this review, we present the role of nerve growth factor (NGF in pain generation, relationship between NGF and OA pain, and pathogenic factors (interleukin-1β, transforming growth factor-β1, mechanical loading, and adipokines involved in OA development. Since NGF blocking is an efficient way to inhibit OA-associated pain, we summarize four categories of drugs that target NGF/tropomyosin receptor kinase A (TrkA signaling. In addition, we discuss the future of NGF/TrkA antagonists and underline their potential for use in OA pain relief. A better understanding of the causes and treatment of OA will facilitate the development of more effective methods of OA pain management. Keywords: osteoarthritis, pain, nerve growth factor, TRPV1, TrkA 

  3. Small-molecule BH3 mimetic and pan-Bcl-2 inhibitor AT-101 enhances the antitumor efficacy of cisplatin through inhibition of APE1 repair and redox activity in non-small-cell lung cancer

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    Ren T

    2015-06-01

    Full Text Available Tao Ren,1–3,* Jinlu Shan,1,* Mengxia Li,1 Yi Qing,1 Chengyuan Qian,4 Guangjie Wang,5 Qing Li,1,3 Guoshou Lu,1 Chongyi Li,1 Yu Peng,1 Hao Luo,1 Shiheng Zhang,1 Yuxing Yang,1 Yi Cheng,1 Dong Wang,1 Shu-Feng Zhou31Cancer Center, Daping Hospital and Research Institute of Surgery, Third Military Medical University, Chongqing, 2Department of Oncology, The Affiliated Hospital, North Sichuan Medical College, Sichuan, People’s Republic of China; 3Department of Pharmaceutical Sciences, College of Pharmacy, University of South Florida, Tampa, FL, USA; 4Department of Oncology, The 97 Hospital of PLA, Jiangsu, 5Cancer Diagnosis and Treatment Center, Military District General Hospital of Chengdu Military Region, Sichuan, People’s Republic of China*These authors contributed equally to this workAbstract: AT-101 is a BH3 mimetic and pan-Bcl-2 inhibitor that has shown potent anticancer activity in non-small-cell lung cancer (NSCLC in murine models, but failed to show clinical efficacy when used in combination with docetaxel in NSCLC patients. Our recent study has demonstrated that AT-101 enhanced the antitumor effect of cisplatin (CDDP in a murine model of NSCLC via inhibition of the interleukin-6/signal transducer and activator of transcription 3 (STAT3 pathway. This study explored the underlying mechanisms for the enhanced anticancer activity of CDDP by AT-101. Our results show that, when compared with monotherapy, AT-101 significantly enhanced the inhibitory effects of CDDP on proliferation and migration of A549 cells and on tube formation and migration in human umbilical vein endothelial cells. AT-101 promoted the proapoptotic activity of CDDP in A549 cells. AT-101 also enhanced the inhibitory effect of CDDP on DNA repair and redox activities of apurinic/apyrimidinic endonuclease 1 (APE1 in A549 cells. In tumor tissues from nude mice treated with AT-101 plus CDDP or monotherapy, the combination therapy resulted in greater inhibition of angiogenesis and

  4. There is a Significant Relationship Between Computer Attitudes and Library Anxiety Among African American Graduate Students. A review of: Jiao, Qun G., and Anthony J. Onwuegbuzie. “The Impact of Information Technology on Library Anxiety: The Role of Computer Attitudes.” Information Technology & Libraries 23.4 (Dec. 2004: 138 ‐44.

    Directory of Open Access Journals (Sweden)

    Gill Needham

    2007-03-01

    Full Text Available Objective – To investigate whether African American students’ computer attitudes predict levels of library anxiety. Design – A user study in which two instruments were administered to a group of graduate students to measure computer attitudes and library anxiety. Setting – The College of Education at an historically black college and university in the United States of America. Subjects – Ninety ‐four, predominantly female, African American graduate students, ranging in age from 22 ‐62 years old, and enrolled in either a statistics or a measurement course. Methods – Two instruments, the Computer Attitude Scale (CAS and the Library Anxiety Scale (LAS were administered to all the study participants. The Computer Anxiety Scale contains forty Likert ‐type items that assess individuals’ attitudes toward computers and their use. It includes four scales which can be administered separately: 1. Anxiety or fear of computers 2. Confidence in the ability to use computers 3. Liking or enjoying working with computers 4. Computer usefulnessThe LAS contains forty ‐three, 5 ‐point, Likert ‐format items that assess levels of library anxiety experienced by college students. It also has five subscales as follows: 1. Barriers with staff 2. Affective barriers 3. Comfort with the library 4. Knowledge of the library 5. Mechanical barriers Main results – There were twenty correlations between the library anxiety subscale scores and the computer attitude subscale scores. Four of these correlations were statistically significant. Liking or enjoying working with computers was statistically significantly linked to affective barriers, comfort with the library, and knowledge of the library. There was also a statistically significant association between an attitude of computer usefulness and knowledge of the library. Conclusion – These findings suggest that in this group of students there is a medium to strong relationship between computer attitudes and library anxiety.

  5. Development of the scintillator-based probe for fast-ion losses in the HL-2A tokamak

    Science.gov (United States)

    Zhang, Y. P.; Liu, Yi; Luo, X. B.; Isobe, M.; Yuan, G. L.; Liu, Y. Q.; Hua, Y.; Song, X. Y.; Yang, J. W.; Li, X.; Chen, W.; Li, Y.; Yan, L. W.; Song, X. M.; Yang, Q. W.; Duan, X. R.

    2014-05-01

    A new scintillator-based lost fast-ion probe (SLIP) has been developed and operated in the HL-2A tokamak [L. W. Yan, X. R. Duan, X. T. Ding, J. Q. Dong, Q. W. Yang, Yi Liu, X. L. Zou, D. Q. Liu, W. M. Xuan, L. Y. Chen, J. Rao, X. M. Song, Y. Huang, W. C. Mao, Q. M. Wang, Q. Li, Z. Cao, B. Li, J. Y. Cao, G. J. Lei, J. H. Zhang, X. D. Li, W. Chen, J. Chen, C. H. Cui, Z. Y. Cui, Z. C. Deng, Y. B. Dong, B. B. Feng, Q. D. Gao, X. Y. Han, W. Y. Hong, M. Huang, X. Q. Ji, Z. H. Kang, D. F. Kong, T. Lan, G. S. Li, H. J. Li, Qing Li, W. Li, Y. G. Li, A. D. Liu, Z. T. Liu, C. W. Luo, X. H. Mao, Y. D. Pan, J. F. Peng, Z. B. Shi, S. D. Song, X. Y. Song, H. J. Sun, A. K. Wang, M. X. Wang, Y. Q. Wang, W. W. Xiao, Y. F. Xie, L. H. Yao, D. L. Yu, B. S. Yuan, K. J. Zhao, G. W. Zhong, J. Zhou, J. C. Yan, C. X. Yu, C. H. Pan, Y. Liu, and the HL-2A Team, Nucl. Fusion 51, 094016 (2011)] to measure the losses of neutral beam ions. The design of the probe is based on the concept of the α-particle detectors on Tokamak Fusion Test Reactor (TFTR) using scintillator plates. The probe is capable of traveling across an equatorial plane port and sweeping the aperture angle rotationally with respect to the axis of the probe shaft by two step motors, in order to optimize the radial position and the collimator angle. The energy and the pitch angle of the lost fast ions can be simultaneously measured if the two-dimensional image of scintillation light intensity due to the impact of the lost fast ions is detected. Measurements of the fast-ion losses using the probe have been performed during HL-2A neutral beam injection discharges. The clear experimental evidence of enhanced losses of beam ions during disruptions has been obtained by means of the SLIP system. A detailed description of the probe system and the first experimental results are reported.

  6. High-throughput sequencing of 16S rDNA amplicons characterizes bacterial composition in bronchoalveolar lavage fluid in patients with ventilator-associated pneumonia

    Directory of Open Access Journals (Sweden)

    Yang XJ

    2015-08-01

    Full Text Available Xiao-Jun Yang,1,* Yan-Bo Wang,2,3,* Zhi-Wei Zhou,4,* Guo-Wei Wang,2 Xiao-Hong Wang,1 Qing-Fu Liu,1 Shu-Feng Zhou,4 Zhen-Hai Wang2,3 1Department of Intensive Care Unit, 2Neurology Center, General Hospital of Ningxia Medical University, Yinchuan, Ningxia, People’s Republic of China; 3Key Laboratory of Brain Diseases of Ningxia, Yinchuan, Ningxia, People’s Republic of China; 4Department of Pharmaceutical Sciences, College of Pharmacy, University of South Florida, Tampa, FL, USA *These authors contributed equally to this work Abstract: Ventilator-associated pneumonia (VAP is a life-threatening disease that is associated with high rates of morbidity and likely mortality, placing a heavy burden on an individual and society. Currently available diagnostic and therapeutic approaches for VAP treatment are limited, and the prognosis of VAP is poor. The present study aimed to reveal and discriminate the identification of the full spectrum of the pathogens in patients with VAP using high-throughput sequencing approach and analyze the species richness and complexity via alpha and beta diversity analysis. The bronchoalveolar lavage fluid samples were collected from 27 patients with VAP in intensive care unit. The polymerase chain reaction products of the hypervariable regions of 16S rDNA gene in these 27 samples of VAP were sequenced using the 454 GS FLX system. A total of 103,856 pyrosequencing reads and 638 operational taxonomic units were obtained from these 27 samples. There were four dominant phyla, including Proteobacteria, Firmicutes, Actinobacteria, and Bacteroidetes. There were 90 different genera, of which 12 genera occurred in over ten different samples. The top five dominant genera were Streptococcus, Acinetobacter, Limnohabitans, Neisseria, and Corynebacterium, and the most widely distributed genera were Streptococcus, Limnohabitans, and Acinetobacter in these 27 samples. Of note, the mixed profile of causative pathogens was observed. Taken

  7. THE LITHOSPHERIC MAGNETIC FIELD ALONG THE NISHAN-GUYANG PROFILE, CHINA 6 datesYuan Jiehao1; Gu Zuowen1; Chen Bin1; Xu Rugang2; Wang Lie2; Wang Can1 1. Institute of Geophysics, China Earthquake Administration(IGP CEA), yjh810405@163.com 2. Anhui Earthquake Administration

    Science.gov (United States)

    Yuan, J.

    2014-12-01

    In order to research the lithospheric magnetic field and the magnetization structure, the geomagnetic field was surveyed along the Nishan-Guyang profile with 900 km long in the Neimenggu and Shanxi provinces in China. The distance between the adjacent geomagnetic sites is about 7 km along the profile. The geomagnetic data were analyzed, and the lithospheric magnetic field was obtained. Using the upward continuation method, the geomagnetic anomalies in different depths were obtained: the basement anomaly, the upper crust anomaly and the superficial anomaly. Basing on these geomagnetic anomalies, the magnetization structure was obtained by using the software of the ModelVision 11.0. The preliminary results show: (1) The geomagnetic anomalies have good relationship with the local geological structure. (2) The magnetization structure is related to the depth variation of the Curie interface, the values of the magnetic susceptibility, the seismic activity and the tectonic block.

  8. Job burnout and organizational justice among medical interns in Shanghai, People’s Republic of China

    Directory of Open Access Journals (Sweden)

    Jin WM

    2015-08-01

    Full Text Available Wei-Min Jin,1 Ying Zhang,2 Xiao-Ping Wang1 1Department of Neurology, Shanghai General Hospital, 2Department of Neuroscience, Shanghai Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, People’s Republic of ChinaBackground: New challenges are occurring in the medical education in Mainland China, and the main risk is the loss of excellent physician candidates. This is due to lack of respect; a large, strong labor force; relatively low remuneration; unstable relationships between patients and doctors; pressures from the public media; and the possible existence of organizational injustice within the hospital. The study reported here looked at one of the in-hospital risks, psychological job burnout and organizational justice, to identify the possible internal cause–effect relationship at the two major general hospitals both affiliated to Shanghai Jiao Tong University School of Medicine.Objective: The aim of the reported study was to analyze the related factors associated with job burnout in Chinese medical interns in Shanghai and to provide some suggestions to better their occupational development.Methods: A total of 135 medical interns were investigated and assessed by the Organizational Justice Scale and the Maslach Burnout Inventory – General Survey.Results: There was a statistically significant negative correlation between organizational justice and job burnout (r=-0.298, P=0.000, suggesting the existence of job burnout among the participant interns. In particular, emotional exhaustion and cynicism were statistically more significant; the comparison between the N group (from Nanjing and S group (Shanghai showed significant difference in participation and reduced professional efficacy (P<0.05, with reduced professional efficacy in N group more significant than in S group, and participation in S group more significant than in N group.Conclusion: Job burnout existed among Chinese medical interns, and was associated

  9. Ginkgo biloba extract mitigates liver fibrosis and apoptosis by regulating p38 MAPK, NF-κB/IκBα, and Bcl-2/Bax signaling

    Directory of Open Access Journals (Sweden)

    Wang YY

    2015-12-01

    Full Text Available Yuanyuan Wang, Rong Wang, Yujie Wang, Ruqin Peng, Yan Wu, Yongfang Yuan Department of Pharmacy, Shanghai 9th People’s Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, People’s Republic of China Background: Liver fibrosis is the consequence of diverse liver injuries and can eventually develop into liver cirrhosis. Ginkgo biloba extract (GBE is an extract from dried ginkgo leaves that has many pharmacological effects because of its various ingredients and has been shown to be hepatoprotective. Purpose and methods: Aimed to investigate the underlying protective mechanisms of GBE on carbon tetrachloride (CCl4-induced liver fibrosis in rats. Male Sprague Dawley rats were randomly divided into four groups: control group (C, model group (M, low-dose group (L, and high-dose group (H. Liver fibrosis was induced by CCl4 groups M, L, and H: group C was administered saline. In addition, GBE at different doses was used to treat groups L and H. Results: The results of hematoxylin and eosin staining, Masson’s trichrome staining, a liver function index, and a liver fibrosis index showed that GBE application noticeably mitigated fibrosis and improved the function of the liver. The western blotting and immunohistochemistry analyses indicated that GBE reduced liver fibrosis not only by inhibiting p38 MAPK and NF-κBp65 via inhibition of IκBα degradation but also by inhibiting hepatocyte apoptosis via downregulation of Bax, upregulation of Bcl-2, and subsequent inhibition of caspase-3 activation. Inflammation-associated factors and hepatic stellate cell (HSC-activation markers further demonstrated that GBE could effectively inhibit HSC activation and inflammation as a result of its regulation of p38 MAPK and nuclear factor-kappa B/IκBα signaling. Conclusion: Our findings indicated a novel role for GBE in the treatment of liver fibrosis. The potential mechanisms may be associated with the following signaling pathways: 1 the p38 MAPK

  10. FAT10 is associated with the malignancy and drug resistance of non-small cell lung cancer

    Directory of Open Access Journals (Sweden)

    Xue F

    2016-07-01

    Full Text Available Feng Xue,1,2,* Lin Zhu,3,* Qing-wei Meng,1 Liyan Wang,2 Xue-song Chen,1 Yan-bin Zhao,1 Ying Xing,1 Xiao-yun Wang,1 Li Cai1 1The Fourth Department of Medical Oncology, Harbin Medical University Cancer Hospital, 2Department of Medical Oncology, Heilongjiang Provincial Hospital, 3Department of Radiotherapy, Harbin Medical University Cancer Hospital, Harbin, People’s Republic of China *These authors contributed equally to this work Abstract: Lung cancer has become one of the leading causes of cancer mortality worldwide, and non-small-cell lung cancer (NSCLC accounts for ~85% of all lung cancer cases. Currently, platinum-based chemotherapy drugs, including cisplatin and carboplatin, are the most effective treatment for NSCLC. However, the clinical efficacy of chemotherapy is markedly reduced later in the treatment because drug resistance develops during the treatment. Recently, a series of studies has suggested the involvement of FAT10 in the development and malignancy of multiple cancer types. In this study, we focused our research on the function of FAT10 in NSCLC, which has not been previously reported in the literature. We found that the expression levels of FAT10 were elevated in quick chemoresistance NSCLC tissues, and we demonstrated that FAT10 promotes NSCLC cell proliferation, migration, and invasion. Furthermore, the protein levels of FAT10 were elevated in cisplatin- and carboplatin-resistant NSCLC cells, and knockdown of FAT10 reduced the drug resistance of NSCLC cells. In addition, we gained evidence that FAT10 regulates NSCLC malignancy and drug resistance by modulating the activity of the nuclear factor kappa B signaling pathway. Keywords: FAT10, NSCLC, malignancy, drug resistance, NFκB

  11. Yearning for the Lost Paradise: The "Great Unity" (datong and Its Philosophical Interpretations

    Directory of Open Access Journals (Sweden)

    Bart DESSEIN

    2017-01-01

    Full Text Available In the course of China’s history, the term datong (great unity has been interpreted in multiple ways. This article first discusses the concept as understood in the Liji, and then focuses on the way in which the perceived loss of the “great unity” within “all-under-heaven” (tianxia at the end of the Qing dynasty (1644–1911, and the endeavor to reconstruct the empire as a modern nation-state starting in the early twentieth century, informed the way the term datong was interpreted. After discussing the interpretations by Wang Tao (1828–1897, Hong Xiuquan (1813–1864, Kang Youwei (1858–1927, Liang Qichao (1873–1929, Sun Zhongshan (1866–1925, and Mao Zedong (1893–1976, this work concludes with a discussion on how, against the background of the perceived threat of loss of national unity that characterizes the contemporary People’s Republic of China, a New Confucian interpretation is developed.

  12. Toxoplasmosis complicating lung cancer: a case report

    Directory of Open Access Journals (Sweden)

    Lu NH

    2015-01-01

    Full Text Available Nianhong Lu, Caihong Liu, Jiangyuan Wang, Ying Ding, Qing Ai Department of Clinical Laboratory, The First Hospital of Jilin University, Changchun, People’s Republic of China Abstract: Toxoplasmosis complicating lung cancer has been described only rarely. Here, we report a case of acute Toxoplasma gondii infection in a patient with squamous lung cancer. A 64-year-old woman was admitted to our hospital with a history of cough of 6 months' duration and chest pain of 1 week’s duration. Further examination revealed multiple swollen lymph nodes, palpable on the top of the right collarbone and without tenderness. The chest X-ray, bronchoscopy, and computed tomography scan confirmed squamous carcinoma of the right lung. The Wright-stained bronchoalveolar-lavage fluid cytology diagnosis was positive for T. gondii and tachyzoites were detected. All of them were of free type (ectocytic, without intracellular parasites. Serological examination revealed that the anti-T. gondii immunoglobulin (Ig M and IgG antibodies were positive. Unfortunately the patient did not continue treatment and was lost to follow-up. Toxoplasmosis is a life-threatening opportunistic infection in patients with lung cancer. Prompt recognition of T. gondii infection among cancer patients with subsequent targeted treatment of toxoplasmosis could help alleviate symptoms and improve survival. Keywords: lung cancer, Toxoplasma gondii, bronchoalveolar-lavage fluid, tachyzoite

  13. Altered baseline brain activity in children with bipolar disorder during mania state: a resting-state study

    Directory of Open Access Journals (Sweden)

    Lu D

    2014-02-01

    Full Text Available Dali Lu,1 Qing Jiao,2 Yuan Zhong,3,4 Weijia Gao,1 Qian Xiao,1 Xiaoqun Liu,1 Xiaoling Lin,5 Wentao Cheng,6 Lanzhu Luo,6 Chuanjian Xu,3 Guangming Lu,2 Linyan Su1 1Mental Health Institute of the Second Xiangya Hospital, Key Laboratory of Psychiatry and Mental Health of Hunan Province, Central South University, Changsha, People's Republic of China; 2Department of Radiology, Taishan Medical University, Taian, People's Republic of China; 3Department of Medical Imaging, Jinling Hospital, Nanjing University School of Medicine, Nanjing, People's Republic of China; 4School of Psychology, Nanjing Normal University, Nanjing, People's Republic of China; 5School of Nursing of Central South University, Changsha, People's Republic of China; 6Department of Pediatric and Geriatric Psychiatry, Fuzhou Neuropsychiatric Hospital, Fuzhou, People's Republic of China Background: Previous functional magnetic resonance imaging (fMRI studies have shown abnormal functional connectivity in regions involved in emotion processing and regulation in pediatric bipolar disorder (PBD. Recent studies indicate, however, that task-dependent neural changes only represent a small fraction of the brain's total activity. How the brain allocates the majority of its resources at resting state is still unknown. We used the amplitude of low-frequency fluctuation (ALFF method of fMRI to explore the spontaneous neuronal activity in resting state in PBD patients. Methods: Eighteen PBD patients during the mania phase and 18 sex-, age- and education-matched healthy subjects were enrolled in this study and all patients underwent fMRI scanning. The ALFF method was used to compare the resting-state spontaneous neuronal activity between groups. Correlation analysis was performed between the ALFF values and Young Mania Rating Scale scores. Results: Compared with healthy controls, PBD patients presented increased ALFF in bilateral caudate and left pallidum as well as decreased ALFF in left precuneus

  14. Proceedings – Mathematical Sciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Proceedings – Mathematical Sciences. XIAOXIANG JIAO. Articles written in Proceedings – Mathematical Sciences. Volume 118 Issue 3 August 2008 pp 381-388. Holomorphic Two-Spheres in Complex Grassmann Manifold (2, 4) · Xiaowei Xu Xiaoxiang Jiao · More Details Abstract Fulltext PDF.

  15. Maternal high-fat diet during pregnancy and lactation affects hepatic ...

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences; Volume 42; Issue 2 ... Shanghai, China; 3Shanghai Key Laboratory of Children's Environmental Health, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200092, China; 4Department of Gastroenterology, Xinhua Hospital, Shanghai Jiao Tong University ...

  16. On conformal minimal 2-spheres in complex Grassmann manifold G ...

    Indian Academy of Sciences (India)

    They classified the minimal two-spheres immersed in CPn and proved the rigidity theorems of conformal minimal two-spheres in CPn, but some of these properties are not inherited when the ambient space is G(k, n), k ≥ 2. The pseudo- holomorphic two-spheres in G(k, n) were studied by Jiao and Peng [10], Jiao [11] and.

  17. Percutaneous microwave ablation combined with simultaneous transarterial chemoembolization for the treatment of advanced intrahepatic cholangiocarcinoma

    Directory of Open Access Journals (Sweden)

    Yang GW

    2015-05-01

    Full Text Available Guo-Wei Yang,* Qing Zhao,* Sheng Qian, Liang Zhu, Xu-Dong Qu, Wei Zhang, Zhi-Ping Yan, Jie-Min Cheng, Qing-Xin Liu, Rong Liu, Jian-Hua Wang Department of Interventional Radiology, Zhongshan Hospital, Fudan University, Shanghai, People’s Republic of China *These authors contributed equally to this work Aim: To retrospectively evaluate the safety and efficacy of ultrasound-guided percutaneous microwave ablation (MWA combined with simultaneous transarterial chemoembolization (TACE in the treatment of patients with advanced intrahepatic cholangiocarcinoma (ICC.Methods: All patients treated with ultrasound-guided percutaneous MWA combined with simultaneous TACE for advanced ICC at our institution were included. Posttreatment contrast-enhanced computed tomography and/or magnetic resonance imaging were retrieved and reviewed for tumor response to the treatment. Routine laboratory studies, including hematology and liver function tests were collected and analyzed. Procedure-related complications were reviewed and survival rates were analyzed.Results: From January 2011 to December 2014, a total of 26 advanced ICC patients were treated at our single institute with ultrasound-guided percutaneous MWA combined with simultaneous TACE. There were 15 males and eleven females with an average age of 57.9±10.4 years (range, 43–75 years. Of 26 patients, 20 (76.9% patients were newly diagnosed advanced ICC without any treatment, and six (23.1% were recurrent and treated with surgical resection of the original tumor. The complete ablation rate was 92.3% (36/39 lesions for advanced ICC. There were no major complications observed. There was no death directly from the treatment. Median progression-free survival and overall survival were 6.2 and 19.5 months, respectively. The 6-, 12-, and 24-month survival rates were 88.5%, 69.2%, and 61.5%, respectively.Conclusion: The study suggests that ultrasound-guided percutaneous MWA combined with simultaneous TACE

  18. An open-label, flexible-dose study of paliperidone extended-release in Chinese patients with first-onset psychosis

    Directory of Open Access Journals (Sweden)

    Si TM

    2015-01-01

    Full Text Available TianMei Si,1 QingRong Tan,2 KeRang Zhang,3 Yang Wang,4 Qing Rui4 1Peking University Institute of Mental health, Key Laboratory of Mental Health, Ministry of Health (Peking University, Beijing, 2Fourth Military Medical University, First Hospital, Xi’an, 3Shanxi Medical University, First Hospital, Shanxi, 4Janssen Research and Development, Beijing, People’s Republic of China Background: Antipsychotic medications facilitate the improvement of psychotic symptoms in patients with first-episode psychosis. Paliperidone extended-release (pali-ER, an atypical anti­psychotic, was assessed for efficacy and safety in Chinese patients with first-episode psychosis. Methods: In this 8-week, open-label, single-arm, multicenter study, patients with first-episode psychosis (Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition criteria and a Positive and Negative Syndrome Scale (PANSS total score ≥70 were treated with flexible-dose pali-ER tablets (3–12 mg/day. The primary efficacy endpoint was the percentage of patients with an increase of ≥8 points in Personal and Social Performance (PSP score from baseline to day 56 (8 weeks. Secondary endpoints included reduction in PANSS total score, improvement in Clinical Global Impression-Severity score, PSP score, Subjective Well-being under Neuroleptics Scale score, and relationship between duration of untreated psychosis and PANSS or PSP. Incidences of treatment-emergent adverse events were used to evaluate safety.Results: Overall, 283 of 294 patients (96% achieved a ≥8-point increase in PSP (primary endpoint, analysis set. For the secondary efficacy endpoints, 284/306 patients (93% had a ≥30% reduction in PANSS total score; 266/306 patients (87% achieved a ≤3 Clinical Global Impression-Severity scale score, and 218/294 patients (74% had a PSP score ≥71. The Subjective Well-being under Neuroleptics Scale score was improved from a baseline mean of 72.7 to 94.7 at endpoint. There was a

  19. Sequential treatment with AT-101 enhances cisplatin chemosensitivity in human non-small cell lung cancer cells through inhibition of apurinic/apyrimidinic endonuclease 1-activated IL-6/STAT3 signaling pathway

    Directory of Open Access Journals (Sweden)

    Ren T

    2014-12-01

    Full Text Available Tao Ren,1,2,* Jinlu Shan,1,* Yi Qing,1 Chengyuan Qian,1 Qing Li,1 Guoshou Lu,1 Mengxia Li,1 Chongyi Li,1 Yu Peng,1 Hao Luo,1 Shiheng Zhang,1 Weiwei Zhang,1 Dong Wang,1 Shu-Feng Zhou3 1Cancer Center, Daping Hospital and Research Institute of Surgery, Third Military Medical University, Chongqing, People’s Republic of China; 2Oncology Department, The Affiliated Hospital, North Sichuan Medical College, Nanchong, People’s Republic of China; 3Department of Pharmaceutical Sciences, College of Pharmacy, University of South Florida, Tampa, FL, USA *These authors contributed equally to this work Abstract: AT-101, known as R-(–-gossypol, is a potent anticancer agent, but its chemosensitizing effects remain elusive. The present study aimed to examine whether AT-101 could increase the sensitivity of non-small cell lung cancer A549 cells to cisplatin (CDDP and the underlying mechanisms. We evaluated the efficacy of the sequential treatment with AT-101 and CDDP using both in vitro and in vivo models. Our results showed that as compared to AT-101 or CDDP monotherapy, or AT-101 plus CDDP concurrent treatment, the sequential treatment significantly inhibited cell proliferation and migration and induced tumor cell death. Moreover, the efficacy of the sequential treatment was also confirmed in a mouse A549 xenograft model. Our study revealed that AT-101 inhibited the reduced status of apurinic/apyrimidinic endonuclease 1 (APE1 and attenuated APE1-mediated IL-6/STAT3 signaling activation by decreasing IL-6 protein expression; suppressing the STAT3–DNA binding; and reducing the expression of the downstream antiapoptotic proteins Bcl-2 and Bcl-xL. In conclusion, AT-101 enhances the sensitivity of A549 cells to CDDP in vitro and in vivo through the inhibition of APE1-mediated IL-6/STAT3 signaling activation, providing a rationale for the combined use of AT-101 and CDDP in non-small cell lung cancer chemotherapy. Keywords: AT101, NSCLC, cisplatin

  20. Comprehensive family therapy: an effective approach for cognitive rehabilitation in schizophrenia

    Directory of Open Access Journals (Sweden)

    Cai J

    2015-05-01

    Full Text Available Jun Cai,1 Yi Zhu,1 Weibo Zhang,1 Yanfeng Wang,1 Chen Zhang2 1Center for Disease Control and Prevention, Shanghai Mental Health Center, 2Schizophrenia Program, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, People’s Republic of China Background: Antipsychotic medication has limited abilities to improve the cognitive impairments that accompany schizophrenia. Adding psychosocial treatment may result in marked improvements in cognitive function, as compared to antipsychotic treatment alone. We hypothesized that a combination of individual and family interventions may be a useful cognitive rehabilitation paradigm for schizophrenia.  Materials and methods: An 18-month follow-up clinical trial of 256 stabilized patients with schizophrenia at six communities in Shanghai, People’s Republic of China were randomly assigned to into either a comprehensive family therapy (CFT group or a usual daily care (UDC group. The Repeatable Battery for the Assessment of Neuropsychological Status (RBANS and the Positive and Negative Syndrome Scale (PANSS were the primary outcome instruments for this study.  Results: There was no significant difference between the CFT and UDC for all demographic characteristics at the baseline assessment. During the 18-month follow-up observation, changes in RBANS total score indicated that patients undergoing CFT showed greater improvement from baseline to the follow-up assessments in cognitive function than those in the UDC group (F=9.77, P=0.002. Post hoc analysis showed that the CFT group presented with significant differences in the RBANS total score, immediate memory, visuospatial skill, language, attention, and delayed memory sections compared with the UDC after 18 months of follow-up (all P<0.01.Conclusion: Our findings suggest that CFT can be easily adapted and may prove to be an effective approach for improving cognitive function in patients with schizophrenia. Our program

  1. Protective effect of fucoidan from Fucus vesiculosus on liver fibrosis via the TGF-β1/Smad pathway-mediated inhibition of extracellular matrix and autophagy

    Directory of Open Access Journals (Sweden)

    Li J

    2016-02-01

    Full Text Available Jingjing Li,1 Kan Chen,1 Sainan Li,1 Jiao Feng,1 Tong Liu,1 Fan Wang,1 Rong Zhang,1,2 Shizan Xu,1,2 Yuqing Zhou,1,3 Shunfeng Zhou,1,3 Yujing Xia,1 Jie Lu,1 Yingqun Zhou,1 Chuanyong Guo1 1Department of Gastroenterology, Shanghai Tenth People’s Hospital, Tongji University School of Medicine, Shanghai, 2The First Clinical Medical College of Nanjing Medical University, Nanjing, 3Department of Gastroenterology, The First Affiliated Hospital of Soochow University, Suzhou, People’s Republic of China Abstract: Liver fibrosis is a dynamic reversible pathological process in the development of chronic liver disease to cirrhosis. However, the current treatments are not administered for a long term due to their various side effects. Autophagy is initiated to decompose damaged or excess organelles, which had been found to alter the progression of liver fibrosis. In this article, we hypothesized that fucoidan from Fucus vesiculosus may attenuate liver fibrosis in mice by inhibition of the extracellular matrix and autophagy in carbon tetrachloride- and bile duct ligation-induced animal models of liver fibrosis. The results were determined using enzyme-linked immunosorbent assay, quantitative real-time polymerase chain reaction, Western blotting, and immunohistochemical staining. Fucoidan from F. vesiculosus could inhibit the activation of hepatic stellate cells and the formation of extracellular matrix and autophagosomes, and its effect may be associated with the downregulation of transforming growth factor beta 1/Smads pathways. Fucoidan, as an autophagy and transforming growth factor beta 1 inhibitor, could be a promising potential therapeutic agent for liver fibrosis. Keywords: liver cirrhosis, hepatic stellate cells, bile duct ligation

  2. RNA sequencing identifies gene expression profile changes associated with β-estradiol treatment in U2OS osteosarcoma cells

    Directory of Open Access Journals (Sweden)

    Chen B

    2017-07-01

    Full Text Available Bin Chen, Zude Liu, Jidong Zhang, Hantao Wang, Bo Yu Department of Orthopedic Surgery, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, People’s Republic of China Abstract: This study was conducted to identify gene expression profile changes associated with β-estradiol (E2 treatment in U2OS osteosarcoma cells by high-throughput RNA sequencing (RNA-seq. Two U2OS cell samples treated with E2 (15 µmol/L and two untreated control U2OS cell samples were subjected to RNA-seq. Differentially expressed genes (DEGs between the groups were identified, and main biological process enrichment was performed using gene ontology (GO analysis. A protein–protein interaction (PPI network was constructed using Cytoscape based on the Human Protein Reference Database. Finally, NFKB1 expression was confirmed by quantitative real-time polymerase chain reaction (qRT-PCR. The map ratios of the four sequenced samples were >65%. In total, 128 upregulated and 92 downregulated DEGs were identified in E2 samples. After GO enrichment, the downregulated DEGs, such as AKT1, were found to be mainly enriched in cell cycle processes, whereas the upregulated DEGs, such as NFKB1, were involved in the regulation of gene expression. Moreover, AKT1 (degree =117 and NFKB1 (degree =72 were key nodes with the highest degrees in the PPI network. Similarly, the results of qRT-PCR confirmed that E2 upregulated NFKB1 expression. The results suggest that E2 upregulates the expression of NFKB1, ATF7IP, and HDAC5, all of which are involved in the regulation of gene expression and transcription, but downregulates that of TCF7L2, ALCAM, and AKT, which are involved in Wnt receptor signaling through β-catenin and morphogenesis in U2OS osteosarcoma cells. Keywords: differentially expressed genes, Wnt receptor signaling, β-catenin, protein-protein interaction network

  3. Distribution of Bathyarchaeota (MCG) archaea in the South China Sea sediments and implication of its ecological roles

    Science.gov (United States)

    Tiantian, Y.; Wang, F.; MingYang, N.

    2015-12-01

    Tiantian Yu1,2, Mingyang Niu1,2 and Fengping Wang1,2 1State Key Laboratory of Microbial Metabolism, School of Life Sciences and Biotechnology, Shanghai, 200240, China; 2State Key Laboratory of Ocean Engineering, Shanghai Jiao Tong University, Shanghai, 200240, China ABSTRACT: Archaea of Bathyarchaeota Phylum (Miscellaneous Crenarchaeotal Group, MCG) are widespread and abundant in various marine and continental environments. However, very little is understood on the metabolisms and ecological roles of this cosmopolitan sedimentary archaea , partly due to obstacles of cultivation. Bathyarchaeota could be divided into large members of subgroups with potentially high genetic heterogeneity, implying different metabolic capabilities and functions in different subgroups. Here, we report our work on investigating Bathyarchaeota abundance and types of subgroups in the South China Sea(SCS) sediments, aim to understand their ecological roles in the carbon cycling. Bathyarchaeota were found the most dominant archaeal group in the sediments of SCS , most of which belong to subgroups MCG-8, MCG-15, MCG-17 and MCG-3. A new pair of 16S rRNA gene primers was designed as the published primers could not cover MCG-15 and MCG-17, which are the most dominant subgroups in the SCS sediments. Comparing with previous primers which used for quantifying the abundance of Bathyarchaeota via Q-PCR, the new primer revealed about an order of magnitude higher abundance in all South China Sea sediments. The relationship of geochemical parameters and MCG subgroups will further be explored to provide the basis for further understanding the metabolic function and biogeochemical roles of these poor-understood sedimentary archaea.

  4. Expression of phosphatase of regenerating liver-3 is associated with prognosis of Wilms’ tumor

    Directory of Open Access Journals (Sweden)

    Sun F

    2017-01-01

    Full Text Available Fengyin Sun,1 Wenyi Li,2,3 Lie Wang,2 Changfeng Jiao3 1Department of Pediatric Surgery, Qilu Hospital, Shandong University, Jinan, Shandong Province, 2Department of General Surgery, Fuzhou General Hospital of Nanjing Command, PLA, Fuzhou, Fujian Province, 3Department of Vascular Surgery, Xinzhou City People’s Hospital, Xinzhou, Shanxi Province, People’s Republic of China Objective: The current study was undertaken to explore the clinical and prognostic value of phosphatase of regenerating liver-3 (PRL-3 expression in Wilms’ tumor. Methods: Seventy-six patients with Wilms’ tumor in Qilu Hospital from January 2003 to July 2009 were enrolled in the study. Protein expression level of PRL-3 was examined by immunohistochemical staining, and the correlation between PRL-3 expression and histopathological parameters, clinical variables, and outcome of patients with Wilms’ tumor were analyzed. Results: We found that 19% of patients with unfavorable histology had tumor recurrence and 16% of patients died following the operation. PRL-3 was expressed in 15 out of 76 tumors (19% and expressed highly in unfavorable histology Wilms’ tumor (P=0.04. PRL-3 protein expression level was correlated to 2.5-fold increase in recurrence rate of Wilms’ tumor (P=0.06 without any statistically significant difference. However, in favorable histology Wilms’ tumor, PRL-3 expression was correlated to an increase of 3.4-fold in recurrence rate (P=0.03. Conclusion: The expression of PRL-3 protein was correlated with an increased recurrence rate of favorable histology Wilms’ tumor. PRL-3 may serve as a promising biomarker for predicting patients with high risk of Wilms’ tumor. Further investigations are warranted to investigate the clinical function of PRL-3 in Wilms’ tumor. Keywords: Wilms’ tumor, prognosis, tumorigenesis, recurrence

  5. The safety issues and hardware-related complications of deep brain stimulation therapy: a single-center retrospective analysis of 478 patients with Parkinson’s disease

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    Zhang J

    2017-06-01

    Full Text Available Jing Zhang,1,* Tao Wang,1,* Chen-cheng Zhang,1 Kristina Zeljic,2 Shikun Zhan,1 Bo-min Sun,1 Dian-you Li1 1Department of Functional Neurosurgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, 2Institute of Neuroscience, Chinese Academy of Sciences, Shanghai, China *These authors contributed equally to this work Introduction: Deep brain stimulation (DBS is a well-established therapy for the treatment of advanced Parkinson’s disease (PD in patients experiencing motor fluctuations and medication-refractory tremor. Despite the relative tolerability and safety of this procedure, associated complications and unnatural deaths are still unavoidable.Methods: In this study, hardware-related complications and the causes of unnatural death were retrospectively analyzed in 478 patients with PD who were treated with DBS.Results: The results showed a 3-year survival rate of 98.6% and a 5-year survival rate of 96.4% for patients with PD who underwent DBS treatment at the study center. Pneumonia was the cause of death with the highest frequency. Prophylactic antibiotics and steroids or antihistamine drugs were adopted to reduce the risk of infection. Twenty-two patients (4.6% experienced hardware-related complications.Conclusion: Deaths of PD patients who receive DBS are typically unrelated to the disease itself or complications associated with the surgery. Pneumonia, malignant tumors, asphyxia, and multiple-organ failure are the common causes of death. Swallowing-related problems may be the most important clinical symptom in late-stage PD, as they cannot be stabilized or improved by DBS alone, and are potentially lethal. Although prophylactic antibiotics and steroids or antihistamine drugs may reduce the risk of infection, it is imperative to identify high-risk patients for whom a therapeutic approach not requiring an implantable device is more suitable, for example, pallidotomy and potentially transcranial ultrasound. Keywords: motor

  6. ER-positive breast cancer patients with more than three positive nodes or grade 3 tumors are at high risk of late recurrence after 5-year adjuvant endocrine therapy

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    Song F

    2017-10-01

    Full Text Available Fangbin Song,1 Jianbing Zhang,2 Shanbao Li,1 Junyi Wu,1 Tao Jin,1 Jun Qin,1 Ye Wang,1 Min Wang,1 Junming Xu1 1Department of General Surgery, 2Department of Pathology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, People’s Republic of China Purpose: Currently, although several clinical trials available give strong suggestions that extension of endocrine therapy has benefits, the risk level at which patients may benefit from extended endocrine therapy remains uncertain. This study aimed to identify the proportion of patients at a substantial risk of late recurrence after 5-year adjuvant endocrine therapy.Patients and methods: We reviewed 1,056 female patients with primary breast cancer who underwent curative resection between January 2006 and December 2011. Univariate and multivariate analyses were performed using the Cox proportional hazards regression model to identify prognostic factors.Results: A total of 327 eligible patients were eventually enrolled in this study. Among them, 42 (12.8% patients suffered from distant metastasis and 34 (10.4% patients experienced locoregional recurrence after 5-year adjuvant endocrine therapy. In multivariate analysis, patients with more than three positive nodes (hazard ratio [HR] =2.176, 95% CI=1.071–4.421; P=0.032 and histologic grade 3 disease (HR=2.098, 95% CI=1.300–3.385; P=0.002 were significantly associated with high risk of late recurrence. However, only histologic grade 3 (HR=2.212, 95% CI=1.166–4.194; P=0.015 was significantly associated with high risk of distant metastasis.Conclusion: Late relapse after completion of 5-year adjuvant endocrine therapy was still common, and grade 3 and more than three positive nodes were the risk factors of late recurrence, while grade 3 was the only risk factor of late distant metastasis. These patients might benefit from extended endocrine therapy. Keywords: Ki-67, breast neoplasms, prognosis, extended endocrine

  7. Aging-related rotenone-induced neurochemical and behavioral deficits: role of SIRT2 and redox imbalance, and neuroprotection by AK-7

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    Wang X

    2015-05-01

    Full Text Available Xijin Wang,1 Qiang Guan,2 Meihua Wang,1 Liu Yang,1 Jie Bai,1 Zhiqiang Yan,3 Yuhong Zhang,4 Zhenguo Liu11Department of Neurology, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, 2Department of Neurology, Tongji Hospital, Tongji University, 3Shanghai Laboratory Animal Center, Chinese Academy of Sciences, 4Department of Neurology, Shanghai Tenth People’s Hospital, Tongji University, Shanghai, People’s Republic of ChinaAbstract: Aging is one of the strongest risk factors for Parkinson’s disease (PD. SIRT2 has been implicated in the aging process. It is pertinent to investigate the role of SIRT2 in aging-related dopaminergic neurotoxicity and to develop effective therapeutic strategies for PD through the use of aging animals. In this study, we observed that rotenone induced significant behavior abnormality and striatal dopamine depletion in aging rats, while it did not do so in young rats. No significant change in striatal serotonin level was observed in the aging rats after rotenone administration. There was also aging-related rotenone-induced increase in substantia nigra (SN SIRT2 expression in the rats. In addition, there was aging-related rotenone-induced SN malondialdehyde (MDA increase and glutathione (GSH decrease in the rats. No significant changes in cerebellar SIRT2, MDA, or GSH levels were observed in the aging rats after rotenone administration. Striatal dopamine content was significantly inversely correlated with SN SIRT2 expression in the rats. AK-7 significantly diminished striatal dopamine depletion and improved behavior abnormality in the rotenone-treated aging rats. Furthermore, AK-7 significantly decreased MDA content and increased GSH content in the SN of rotenone-treated aging rats. Finally, the effect of AK-7 on dopaminergic neurons and redox imbalance was supported by the results from primary mesencephalic cultures. Our study helps to elucidate the mechanism for the participation of aging

  8. Comment on: "Crustal strength in central Tibet determined from Holocene shoreline deflection around Siling Co" by Xuhua Shi, Eric Kirby, Kevin P. Furlong, Kai Meng, Ruth Robinson and Erchie Wang

    Science.gov (United States)

    England, Philip C.; Walker, Richard T.

    2016-01-01

    Shi et al. (2015) analysed the distributions of elevation of palaeoshorelines around Siling Tso, central Tibet assuming a model in which surface loads are entirely supported by an elastic lid overlying an inviscid fluid. They concluded that the thickness of the elastic lid is 20-30 km and that, for the assumption of an inviscid substrate in this model to be valid, the viscosity of the crust below the elastic lid must be less than 1- 2 ×1019 Pas. Here we relax the assumption of an inviscid lower crust and show that the distribution of shoreline elevations may be explained either by a thick elastic lid or by high viscosity in the lower crust. In the limit of an inviscid lower crust, the thickness of the elastic lid must be greater than 25 to 39 km. If the elastic lid is thinner than this, then the viscosity of the crust beneath must be at least 5 ×1019 to 2 ×1020 Pas, depending on the time interval over which the lake was loaded.

  9. Dissecting genomic imprinting and genetic conflict from a game theory prospective. Comment on: ;Epigenetic game theory: How to compute the epigenetic control of maternal-to-zygotic transition; by Qian Wang et al.

    Science.gov (United States)

    Cui, Yuehua; Yang, Haitao

    2017-03-01

    Epigenetics typically refers to changes in the structure of a chromosome that affect gene activity and expression. Genomic imprinting is a special type of epigenetic phenomenon in which the expression of an allele depends on its parental origin. When an allele inherited from the mother (or father) is imprinted (i.e., silent), it is termed as maternal (or paternal) imprinting. Imprinting is often resulted from DNA methylation and tends to cluster together in the genome [1]. It has been shown to play a key role in many genetic disorders in humans [2]. Imprinting is heritable and undergoes a reprogramming process in gametes before and after fertilization [1]. Sometimes the reprogramming process is not reversible, leading to the loss of imprinting [3]. Although efforts have been made to experimentally or computationally infer imprinting genes, the underlying molecular mechanism that leads to unbalanced allelic expression is still largely unknown.

  10. Robert Bagley, Max Loehr and the Study of Chinese Bronzes, Ithaca, NY: Cornell East Asia Series, 2008, translated by Wang Haicheng, originally published in Chinese in Dushu, November 2010, 126-33.

    Directory of Open Access Journals (Sweden)

    Miao Zhe

    2011-12-01

    Full Text Available This essay reviews Robert Bagley’s intellectual portrait of Max Loehr, one of the founding fathers of the western study of Chinese art. Bagley’s book centers on the prolonged controversy between Loehr and Bernhard Karlgren over the history of ancient Chinese bronzes. Karlgren, an eminent philologist, tried to extract chronological information from a classification of décor motifs, an approach that he and many of his readers considered to be scientific and objective. Failing to detect any pattern of change in his material, he declared that all extant bronzes were made during two or three centuries of artistic stagnation, centuries that merely repeated designs invented in some earlier and more creative period that is unknown to us. Loehr by contrast succeeded in tracing a clear sequence of evolving styles in the same corpus of material. These positions were first staked out in the 1930s; most observers sided with Karlgren until the 1960s, when archaeology confirmed Loehr’s sequence. What makes the controversy interesting and instructive is that the right answer did not come from the approach that to this day strikes most readers as the scientific one, it came from a seemingly subjective and intuitive art-historical analysis. In part Bagley explains this unexpected outcome by showing that science as Karlgren conceived it—a rule-bound and mechanical procedure that excludes intuition and judgment—is a layman’s misconception; in essential ways, he shows, it was Loehr’s approach rather than Karlgren’s that was scientific. At a time when the prestige of the hard sciences continues to inspire attempts to import scientific methods into the humanities, Bagley has illuminating things to say about the real substance of those methods. He also has much to say about artistic invention and intentionality, and he clarifies one of art history’s most constantly used yet most ill-defined concepts, the concept of style, by arguing that it is not an intrinsic property of an object considered in isolation but only a shorthand way of talking about comparisons.

  11. Applications and extensions of epigenetic game theory. Comment on: ;Epigenetic game theory: How to compute the epigenetic control of maternal-to-zygotic transition; by Qian Wang et al.

    Science.gov (United States)

    Wang, Yaqun

    2017-03-01

    The authors are to be congratulated for a thought-provoking article [1], which reviews the epigenetic game theory (epiGame) that utilizes differential equations to study the epigenetic control of embryo development. It is a novel application of evolutionary game theory and provides biology researchers with useful methodologies to address scientific questions related to biological coordination of competition and cooperation.

  12. 圖書館事業與交流/UCDRS and Trend of CollaboratedReal Time Digital Reference Servicesin China/Hanrong Wang; Zhaohui Xie; Carley Knight

    Directory of Open Access Journals (Sweden)

    Hanrong Wang; Zhaohui Xie; Carley Knight Hanrong Wang; Zhaohui Xie; Carley Knight

    2009-10-01

    Full Text Available The development of computer and Internet technologies provides an alternative way for libraries to better serve their patrons. In addition to traditional reference service, online digital reference is becoming more predominant. Real-time digital reference, another form of online digital reference, allows synchronous communication between patrons and librarians. This reference service was developed in China at the beginning of the 21st century. United Combined Digital Reference Service (UCDRS is currently one of the most visited real-time digital reference services in China. Detailed information on the system work flow, the user and the reference librarian experience, as well as document delivery is discussed in this paper. The authors conclude that UCDRS system of China is a firm and solid example of the trend that is becoming the norm for library reference services in China. 電腦和網路技術的發展,提供圖書館在滿足顧客需求時的另一種服務之道。除了傳統的參考服務,線上數位參考服務也越來越受到重視。作為線上數位參考服務形式之一的“即時數位參考服務”,實現讀者與圖書管理員之間的同步溝通。中國從21 世紀初開始使用即時數位參考服務,「聯合數位參考服務與文獻傳遞服務(UCDRS)」是中國目前使用率最高的即時數位參考服務。本文針對「聯合數位參考服務與文獻傳遞服務(UCDRS)」的系統工作流程、使用者和參考館員的經驗與文件傳遞進行了詳細介紹和探討。作者認為「聯合數位參考服務與文獻傳遞服務(UCDRS)」為目前中國圖書館在參考服務的模範,同時它也代表了中國圖書館參考服務未來的發展趨勢。 頁次:107-115

  13. 專論/數位環境的著作權法制思考/賴文智;王文君 | Rethinking Copyright Law System in Digital Environment / Wen-chi Lai;Wen-chun Wang

    Directory of Open Access Journals (Sweden)

    賴文智、王文君

    2007-04-01

    Full Text Available

    本文研究議題為著作權法制面對數位環境衝擊之制度調整思考。本文首先說明數位與網路科技不僅為當代社會著作利用帶來相當多的變化,也使著作權制度面 臨諸多困難議題。藉由對著作權法制發展史與著作權法第1條規定的檢視,本文提出「促進著作流通利用」乃達致著作權法各項立法目的之共同且最主要之途徑(方 法),並嘗試在此脈絡下,檢視合理使用、公開傳輸權、權利管理電子資訊、防盜拷措施的保護及著作權仲介團體條例等制度設計。最終重申並闡釋「促進著作流通 利用」乃是用以檢視著作權制度是否合於當代社會需求之關鍵。

    At first, this paper raises the question on the impacts of Copyright System in digital environment. From reviewing history of Copyright System and Article 1 of Copyright Act, this paper holds that encouraging circulation and use of copyrighted work is main purpose of Copyright Act. This paper describes that facing digital and network technologies, the use of copyrighted work in our society has several changes. These changes, from the point of view that the main purpose of Copyright System is encouraging circulation and use of copyrighted work, make Copyright System facing several difficult issues. Finally, this paper examines several issues of Copyright System, such as, fair use, right of public transmission, electronic rights management information, protection of technological protection measures and Copyright Intermediary Organization Act. Encouraging circulation and use of copyrighted work is always the key of examining whether the Copyright System fit the need of current society.

    頁次:30-38

  14. Comment on "High-temperature soft magnetic properties of antiperovskite nitrides ZnNFe3 and AlNFe3" by Yankun Fu, Shuai Lin, and Bosen Wang, J. Magn. Magn. Mater. 378 (2015) 54-58

    Science.gov (United States)

    Scholz, T.; Leineweber, A.; Dronskowski, R.

    2016-10-01

    The authors of the aforementioned manuscript have recently claimed the synthesis of the ternary nitrides ZnNFe3 (=ZnFe3N) and AlNFe3 (=AlFe3N), ordered substituted variants of the binary phase γ'-Fe4N [1]. While soft ferromagnets of such kind are presently attracting lots of attention, their history dates back for more than half a century. In particular, Al-substituted γ'-Fe4N has already been mentioned in 1961 [2], and the existence of AlFe3N has also been claimed in 2009 [3] from a two-step ammonolysis reaction combining a high-temperature sintering step and a low-temperature nitriding reaction [4]. Nonetheless, one of us had to withdraw the latter claim after finding out, by means of scanning-electron microscopy and elemental mapping, that all samples of "AlFe3N" consisted of an intimate solid mixture of γ'-Fe4N and amorphous Al2O3[5]. From what follows, we have strong reasons to believe that the authors of Ref. [1] overlooked our findings [5] and also did not synthesize ZnFe3N and AlFe3N.

  15. Integrating evolutionary game theory into epigenetic study of embryonic development. Comment on ;Epigenetic game theory: How to compute the epigenetic control of maternal-to-zygotic transition; by Qian Wang et al.

    Science.gov (United States)

    Wang, Zuoheng

    2017-03-01

    DNA methylation is an essential component in the epigenetic regulation of embryonic development, and plays a crucial role in various biological processes, including repression of gene transcription, parent-of-origin genomic imprinting, and X-chromosome inactivation [1-5]. Understanding the epigenetic processes in different stages of embryo development has become an important research topic in the field. It has potential to offer new insight into reproductive medicine and contribute to the improvement of long-term health outcomes.

  16. Virus-mediated chemical changes in rice plants impact the relationship between non-vector planthopper Nilaparvata lugens Stål and its egg parasitoid Anagrus nilaparvatae Pang et Wang.

    Directory of Open Access Journals (Sweden)

    Xiaochan He

    Full Text Available In order to clarify the impacts of southern rice black-streaked dwarf virus (SRBSDV infection on rice plants, rice planthoppers and natural enemies, differences in nutrients and volatile secondary metabolites between infected and healthy rice plants were examined. Furthermore, the impacts of virus-mediated changes in plants on the population growth of non-vector brown planthopper (BPH, Nilaparvata lugens, and the selectivity and parasitic capability of planthopper egg parasitoid Anagrus nilaparvatae were studied. The results showed that rice plants had no significant changes in amino acid and soluble sugar contents after SRBSDV infection, and SRBSDV-infected plants had no significant effect on population growth of non-vector BPH. A. nilaparvatae preferred BPH eggs both in infected and healthy rice plants, and tended to parasitize eggs on infected plants, but it had no significant preference for infected plants or healthy plants. GC-MS analysis showed that tridecylic aldehyde occurred only in rice plants infected with SRBSDV, whereas octanal, undecane, methyl salicylate and hexadecane occurred only in healthy rice plants. However, in tests of behavioral responses to these five volatile substances using a Y-tube olfactometer, A. nilaparvatae did not show obvious selectivity between single volatile substances at different concentrations and liquid paraffin in the control group. The parasitic capability of A. nilaparvatae did not differ between SRBSDV-infected plants and healthy plant seedlings. The results suggested that SRBSDV-infected plants have no significant impacts on the non-vector planthopper and its egg parasitoid, A. nilaparvatae.

  17. Stress reactivity and emotion in premenstrual syndrome

    Directory of Open Access Journals (Sweden)

    Liu Q

    2017-06-01

    Full Text Available Qing Liu,1 Yongshun Wang,2 Cornelis Hermanus van Heck,3 Wei Qiao4 1Department of Nuclear Medicine and Medical PET Center, The Second Hospital of Zhejiang University School of Medicine, Zhejiang University, Hangzhou, 2School of Physical Education and Sport, Huaqiao University, Xiamen, People’s Republic of China; 3DCC, Donders Institute for Neuroscience and Neurocognition, Arnhem, the Netherlands; 4Department of Physical Education, Xiamen Institute of Technology, Xiamen, People’s Republic of China Background: Hormone level fluctuation across the menstrual cycle causes women to experience negative emotions and also affects their mood regulation and stress sensitivity. However, the stress reactivity and emotional variations in women with premenstrual syndrome (PMS, who are especially sensitive to the variations in hormone cycles, have not been explained. Methods: The present study used an electroencephalogram (EEG stress evaluation test, a physiology stress evaluation test, and the positive affect and negative affect scale (PANAS to evaluate the stress reactivity pattern and emotional state of women with PMS. Results: The results showed that women with PMS had higher negative affect and lower positive affect compared with controls. Moreover, under stressful conditions, the women with PMS had a higher alpha activity and a lower respiration rate than the controls. The differences in stress reactivity and emotional states between women with PMS and controls were based on a covariant analysis with menstrual cycle (luteal and follicular phases as the covariate. Conclusion: The results demonstrated that, compared with controls, women suffering from PMS have a continuous abnormality in emotional state and stress reactivity, which was independent of the menstrual cycle. Keywords: premenstrual syndrome, stress reactivity, emotion, EEG stress evaluation test, physiology stress evaluation test

  18. High expression of HEF1 is associated with poor prognosis in urinary bladder carcinoma

    Directory of Open Access Journals (Sweden)

    Zhang Q

    2014-07-01

    Full Text Available Qi Zhang,1 Hui-Ju Wang,2 Da-Hong Zhang,1 Guo-Qing Ru,3 Xu-Jun He,2 Ying-Yu Ma2 1Department of Urology, 2Key Laboratory of Gastroenterology of Zhejiang Province, 3Department of Pathology, Zhejiang Provincial People's Hospital, Hangzhou, People's Republic of China Abstract: Human enhancer of filamentation 1 (HEF1 is a multidomain scaffolding protein that has been thought to play an important role in the tumor progression of various cancers. HEF1 expression has not previously been reported in urinary bladder carcinoma, and little is known about its prognostic significance. The aim of this study was to evaluate the expression patterns of HEF1 in urinary bladder carcinoma and to investigate its prognostic significance. HEF1 expression was analyzed by immunohistochemistry using tissue microarray. A significant relationship between HEF1 expression and sex, tumor size, number of tumors, invasion depth, lymph node metastasis, and distant metastasis was found, and high expression of HEF1 was associated with worse overall survival when compared to low expression of HEF1. Multivariate analysis showed that HEF1 expression was an independent prognostic factor for overall survival in urinary bladder carcinoma. We investigated HEF1 expression in urinary bladder carcinoma and found that high HEF1 expression was associated with advanced stage, large tumor size, and shortened progression-free survival. Although the biologic function of HEF1 in urinary bladder carcinoma remains unknown, the expression of HEF1 can provide new prognostic information for disease progression. Keywords: human enhancer of filamentation 1, progression-free survival, immunohistochemistry, metastasis, bladder cancer

  19. Hyperthermia combined with 5-fluorouracil promoted apoptosis and enhanced thermotolerance in human gastric cancer cell line SGC-7901

    Directory of Open Access Journals (Sweden)

    Liu T

    2015-05-01

    Full Text Available Tao Liu,* Yan-Wei Ye,* A-li Zhu, Zhen Yang, Yang Fu, Chong-Qing Wei, Qi Liu, Chun-Lin Zhao, Guo-Jun Wang, Xie-Fu Zhang Department of Gastrointestinal Surgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, People’s Republic of China *These authors contributed equally to this work Abstract: This study was designed to investigate the proliferation inhibition and apo­ptosis-promoting effect under hyperthermia and chemotherapy treatment, at cellular level. Human gastric cancer cell line SGC-7901 was cultivated with 5-fluorouracil at different temperatures. Cell proliferation and apoptosis were determined, and expression of Bcl-2 and HSP70 was measured at different treatments. Cell survival rates and inhibition rates in chemotherapy group, thermotherapy group, and thermo-chemotherapy group were drastically lower than the control group (P<0.05. For tumor cells in the thermo-chemotherapy group, survival rates and inhibition rates at three different temperatures were all significantly lower than those in chemotherapy group and thermotherapy group (P<0.05. 5-Fluorouracil induced apoptosis of SGC-7901 cells with a strong temperature dependence, which increased gradually with increase in temperature. At 37°C and 43°C there were significant differences between the thermotherapy group and chemotherapy group and between the thermo-chemotherapy group and thermotherapy group (P<0.01. The expression of Bcl-2 was downregulated and HSP70 was upregulated, with increase in temperature in all groups. Cell apoptosis was not significant at 46°C (P>0.05, which was probably due to thermotolerance caused by HSP70 accumulation. These results suggested that hyperthermia combined with 5-fluorouracil had a synergistic effect in promoting apoptosis and enhancing thermotolerance in gastric cancer cell line SGC-7901. Keywords: gastric cancer, thermotherapy, 5-fluorouracil, Bcl-2, HSP70, thermotolerance

  20. Efficacy of percutaneous transluminal renal angioplasty with stent in elderly male patients with atherosclerotic renal artery stenosis

    Directory of Open Access Journals (Sweden)

    Zhao J

    2012-10-01

    Full Text Available Jiahui Zhao, Qingli Cheng, Xiaoying Zhang, Meihua Li, Sheng Liu, Xiaodan WangDepartment of Geriatric Nephrology, Chinese PLA General Hospital, Beijing, ChinaObjectives: Percutaneous transluminal renal angioplasty with stent implantation (PTRAS has become the treatment of choice for atherosclerotic renal artery stenosis (ARAS. This study evaluates the long-term effects of PTRAS on hypertension and renal function in elderly patients with ARAS.Methods: We conducted a retrospective cohort study of all patients who underwent PTRAS in the geriatric division of a tertiary medical center during the period 2003–2010. The clinical data were extracted from the medical records of each patient. Changes in blood pressure, antihypertensive treatment, and estimated glomerular filtration rate were analyzed before and after PTRAS.Results: Eighty-six stents in 81 elderly patients were placed successfully. The average age of the patients was 76.2 years (65–89 years. Mean follow-up was 31.3 months (range 12 –49 months. There was a significant decrease in both systolic and diastolic blood pressure at the third day after the PTRAS procedure and the reduction in blood pressure was constant throughout the follow-up period until 36 months after PTRAS. However, there was no marked benefit to renal function outcome during the follow-up period. The incidence of contrast-induced nephropathy was 9.9% in this study group. The rate of renal artery restenosis was 14.8%. The survival rate was 96.3% for 4 years after the procedure.Conclusion: It is beneficial to control blood pressure in elderly patients with ARAS up to 36 months after a PTRAS procedure. However, their renal function improvement is limited.Keywords: angioplasty, hypertension, renal function, elderly, renal artery stenosis

  1. Evolution of the defensin-like gene family in grass genomes

    Indian Academy of Sciences (India)

    . Jiandong Wu, Xiaolei Jing, Yang Zhao, Qing Dong, Haiyang Jiang and Qing Ma. J. Genet. 95, 53–62. Table 1. Information about DEFL genes in B. distachyon, O. sativa, S. bicolor and Z. mays. Species. Gene name. Gene identifer. ORF (aa).

  2. Chloroquinone Inhibits Cell Proliferation and Induces Apoptosis in ...

    African Journals Online (AJOL)

    Original Research Article. Chloroquinone Inhibits Cell Proliferation and Induces. Apoptosis in Nasopharyngeal Carcinoma Cell Lines. Xin-Qing Yang, Hao Zheng, Qing Ye, Rui-Yu Li* and Yong Chen. Department of Otolaryngology Head and Neck Surgery, Fujian Provincial Clinical College, Fujian Medical University, China.

  3. Find novel dual-agonist drugs for treating type 2 diabetes by means of cheminformatics

    Directory of Open Access Journals (Sweden)

    Liu L

    2013-04-01

    Full Text Available Lei Liu,1 Ying Ma,2 Run-Ling Wang,2 Wei-Ren Xu,3 Shu-Qing Wang,2,5 Kuo-Chen Chou4,5 1PET/CT Center, General Hospital of Tianjin Medical University, Tianjin, People’s Republic of China; 2Tianjin Key Laboratory on Technologies Enabling Development of Clinical Therapeutics and Diagnostics (Theranostics, School of Pharmacy, Tianjin Medical University, Tianjin, People’s Republic of China; 3Tianjin Institute of Pharmaceutical Research (TIPR, Tianjin, People’s Republic of China; 4Center of Excellence in Genomic Medicine Research (CEGMR, King Abdulaziz University, Jeddah, Saudi Arabia; 5Gordon Life Science Institute, Belmont, MA, USA Abstract: The high prevalence of type 2 diabetes mellitus in the world as well as the increasing reports about the adverse side effects of the existing diabetes treatment drugs have made developing new and effective drugs against the disease a very high priority. In this study, we report ten novel compounds found by targeting peroxisome proliferator-activated receptors (PPARs using virtual screening and core hopping approaches. PPARs have drawn increasing attention for developing novel drugs to treat diabetes due to their unique functions in regulating glucose, lipid, and cholesterol metabolism. The reported compounds are featured with dual functions, and hence belong to the category of dual agonists. Compared with the single PPAR agonists, the dual PPAR agonists, formed by combining the lipid benefit of PPARα agonists (such as fibrates and the glycemic advantages of the PPARγ agonists (such as thiazolidinediones, are much more powerful in treating diabetes because they can enhance metabolic effects while minimizing the side effects. This was observed in the studies on molecular dynamics simulations, as well as on absorption, distribution, metabolism, and excretion, that these novel dual agonists not only possessed the same function as ragaglitazar (an investigational drug developed by Novo Nordisk for treating type

  4. Stereotactic body radiation therapy for patients with recurrent pancreatic adenocarcinoma at the abdominal lymph nodes or postoperative stump including pancreatic stump and other stump

    Directory of Open Access Journals (Sweden)

    Zeng XL

    2016-06-01

    Full Text Available Xian-Liang Zeng,* Huan-Huan Wang,* Mao-Bin Meng, Zhi-Qiang Wu, Yong-Chun Song, Hong-Qing Zhuang, Dong Qian, Feng-Tong Li, Lu-Jun Zhao, Zhi-Yong Yuan, Ping Wang Department of Radiation Oncology, Tianjin’s Clinical Research Center for Cancer and Key Laboratory of Cancer Prevention and Therapy, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Tianjin, People’s Republic of China *These authors contributed equally to this work Background and aim: The aim of this study is to evaluate the efficacy and safety of stereotactic body radiation therapy (SBRT using CyberKnife in the treatment of patients with recurrent pancreatic adenocarcinoma at the abdominal lymph node or stump after surgery. Patients and methods: Between October 1, 2006 and May 1, 2015, patients with recurrent pancreatic adenocarcinoma at the abdominal lymph node or stump after surgery were enrolled and treated with SBRT at our hospital. The primary end point was local control rate after SBRT. Secondary end points were overall survival, time to symptom alleviation, and toxicity, assessed using the Common Terminology Criteria for Adverse Events version 4.0. Results: Twenty-four patients with 24 lesions (17 abdominal lymph nodes and seven stumps were treated with SBRT, of which five patients presented with abdominal lymph nodes and synchronous metastases in the liver and lung. The 6-, 12-, and 24-month actuarial local control rates were 95.2%, 83.8%, and 62.1%, respectively. For the entire cohort, the median overall survival from diagnosis and SBRT was 28.9 and 12.2 months, respectively. Symptom alleviation was observed in eleven of 14 patients (78.6% within a median of 8 days (range, 1–14 days after SBRT. Nine patients (37.5% experienced Common Terminology Criteria for Adverse Events version 4.0 grade 1–2 acute toxicities; one patient experienced grade 3 acute toxicity due to thrombocytopenia. Conclusion: SBRT is a safe and

  5. Retraction Statement: "Overexpression of miR-708 and its targets in the childhood common precursor B-cell ALL" by Xue Li, MMed, Dong Li, PhD, Yong Zhuang, MMed, Qing Shi, BSc, Wei Wei, MMed, and Xiuli Ju, MD, PhD.

    Science.gov (United States)

    2017-05-01

    The above article, published online 23 August 2013 in Pediatric Blood and Cancer, Volume 60, Issue 12, December 2013, Pages 2060-2067, has been retracted by agreement among the authors, the journal's Editor-in-Chief, Peter E. Newburger, M.D., and Wiley Periodicals, Inc. The decision to retract was agreed upon following notification that the paper substantially duplicates a prior study already published in Chinese https://www.ncbi.nlm.nih.gov/pubmed/23611221. The authors were not aware that publication in another language would constitute a duplicate publication and, upon being informed of this fact, have agreed to withdraw the paper from Pediatric Blood and Cancer. Reference Li X, Li D, Zhuang Y, Shi Q, Wei W and Ju X. Overexpression of miR-708 and its targets in the childhood common precursor B-cell ALL. Pediatr Blood Cancer. 2013; 60: 2060-2067. doi:10.1002/pbc.24583. © 2017 Wiley Periodicals, Inc.

  6. Minimal surfaces in symmetric spaces with parallel second ...

    Indian Academy of Sciences (India)

    Author Affiliations. XIAOXIANG JIAO1 MINGYAN LI2. School of Mathematical Sciences, University of Chinese Academy of Sciences, Beijing 101408, China; School of Mathematics and Statistics, Zhengzhou University, Zhengzhou 450001, China ...

  7. Research Area 3 - Mathematical Sciences: Multiscale Modeling of the Mechanics of Advanced Energetic Materials Relevant to Detonation Prediction

    Science.gov (United States)

    2015-08-24

    Michael Pernice, , John Bell,, Jed Brown , , Alain Clo, , Jeffrey Connors, , Emil Constantinescu, , Don Estep,, Kate Evans, , Charbel Farhat, , Ammar...Hakim, , Glenn Hammond, , Glen Hansen,, Judith Hill, , Tobin Isaac, , Xiangmin Jiao, , Kirk Jordan, , Dinesh Kaushik,, Efthimios Kaxiras, , Alice Koniges

  8. Reduction of the Bethe–Salpeter wave function: Fermion–scalar ...

    Indian Academy of Sciences (India)

    Author Affiliations. Chen Chong1 Chen Jiao-Kai2. School of Mathematical Sciences, University of Electronic Science and Technology of China, Chengdu 611731, China; School of Physics and Information Science, Shanxi Normal University, Linfen 041004, China ...

  9. Agama Khonghucu Sejarah, Ajaran, dan Keorganisasiannya di Pontianak Kalimantan Barat

    OpenAIRE

    Sulaiman, Sulaiman

    2009-01-01

    Current confucius religion research is performed at Pontianak, West KalimantanProvince. The research shows that confucius religion characteristics which are moretraditional come from their ancestor’s tradition. The History reveals the beginningof confucius religion invoking from traditional belief, which is Ru Jiao. The prophetKhong Zi has finalized Ru Jiao into Confucius religion. Confucius followers belief inone God, Prophet, and holybook, and belief in forefather. The history of confuciusr...

  10. Curcumin modulates the effect of histone modification on the expression of chemokines by type II alveolar epithelial cells in a rat COPD model

    Directory of Open Access Journals (Sweden)

    Gan L

    2016-11-01

    Full Text Available Lixing Gan,1 Chengye Li,2 Jian Wang,1 Xuejun Guo3 1Department of Respiratory Medicine, Shanghai Ninth People’s Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 2Department of Respiratory Medicine, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, 3Department of Respiratory Medicine, Xin Hua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, People’s Republic of China Background: Studies have suggested that histone modification has a positive impact on various aspects associated with the progression of COPD. Histone deacetylase 2 (HDAC2 suppresses proinflammatory gene expression through deacetylation of core histones.Objective: To investigate the effect of histone modification on the expression of chemokines in type II alveolar epithelial cells (AEC II in a rat COPD model and regulation of HDAC2 expression by curcumin in comparison with corticosteroid.Materials and methods: The rat COPD model was established by cigarette smoke exposure and confirmed by histology and pathophysioloy. AEC II were isolated and cultured in vitro from the COPD models and control animals. The cells were treated with curcumin, corticosteroid, or trichostatin A, and messenger RNA (mRNA expression of interleukin-8 (IL-8, monocyte chemoattractant protein-1 (MCP-1, and macrophage inflammatory protein-2α (MIP-2α was assessed by quantitative real-time polymerase chain reaction (RT-PCR. The expression of HDAC2 was measured by Western blot. Chromatin immunoprecipitation was used to detect H3/H4 acetylation and H3K9 methylation in the promoter region of three kinds of chemokine genes (IL-8, MCP-1, and MIP-2α. Results: Compared to the control group, the mRNAs of MCP-1, IL-8, and MIP-2α were upregulated 4.48-fold, 3.14-fold, and 2.83-fold, respectively, in the AEC II from COPD model. The protein expression of HDAC2 in the AEC II from COPD model was significantly lower than from the control group (P<0

  11. Committees

    Science.gov (United States)

    2012-11-01

    Leadership Team of the IAHR Committee for Hydraulic Machinery and Systems Eduard EGUSQUIZA, UPC Barcelona, Spain, Chair François AVELLAN, EPFL-LMH, Switzerland, Past Chair Richard K FISHER, Voith Hydro Inc., USA, Past Chair Fidel ARZOLA, Edelca, Venezuela Michel COUSTON, Alstom Hydro, France Niklas DAHLBÄCKCK, Vatenfall, Sweden Normand DESY, Andritz VA TECH Hydro Ltd., Canada Chisachi KATO, University of Tokyo, Japan Andrei LIPEJ, Turboinstitut, Slovenija Torbjørn NIELSEN, NTNU, Norway Romeo SUSAN-RESIGA, 'Politehnica' University Timisoara, Romania Stefan RIEDELBAUCH, Stuggart University, Germany Albert RUPRECHT, Stuttgart University, Germany Qing-Hua SHI, Dong Fang Electrical Machinery Co., China Geraldo TIAGO, Universidade Federal de Itajubá, Brazil International Advisory Committee Shouqi YUAN (principal) Jiangsu University China QingHua SHI (principal) Dong Fang Electrical Machinery Co. China Fidel ARZOLA EDELCA Venezuela Thomas ASCHENBRENNER Voith Hydro GmbH & Co. KG Germany Anton BERGANT Litostroj Power doo Slovenia B C BHAOYAL Research & Technology Centre India Hermod BREKKE NTNU Norway Stuart COULSON Voith Hydro Inc. USA Paul COOPER Fluid Machinery Research Inc USA V A DEMIANOV Power Machines OJSC Russia Bart van ESCH Technische Universiteit Eindhoven Netherland Arno GEHRER Andritz Hydro Graz Austria Akira GOTO Ebara Corporation Japan Adiel GUINZBURG The Boeing Company USA D-H HELLMANN KSB AG Germany Ashvin HOSANGADI Combustion Research and Flow Technology USA Byung-Sun HWANG Korea Institute of Material Science Korea Toshiaki KANEMOTO Kyushu Institute of Technology Japan Mann-Eung KIM Korean Register of Shipping Korea Jiri KOUTNIK Voith Hydro GmbH & Co. KG Germany Jinkook LEE Eaton Corporation USA Young-Ho LEE Korea Maritime University Korea Woo-Seop LIM Hyosung Goodsprings Inc Korea Jun MATSUI Yokohama National University Japan Kazuyoshi Mitsubishi H I Ltd, Japan MIYAGAWA Christophe NICOLET Power Vision Engineering Srl Switzerland Maryse PAGE Hydro

  12. The Toronto General Hospital Transitional Pain Service: development and implementation of a multidisciplinary program to prevent chronic postsurgical pain

    Directory of Open Access Journals (Sweden)

    Katz J

    2015-10-01

    Full Text Available Joel Katz,1–3 Aliza Weinrib,1,2 Samantha R Fashler,2 Rita Katznelzon,1,3 Bansi R Shah,1 Salima SJ Ladak,1 Jiao Jiang,1 Qing Li,1 Kayla McMillan,1 Daniel Santa Mina,5,6 Kirsten Wentlandt,7 Karen McRae,1,3 Diana Tamir,1,3 Sheldon Lyn,1,3 Marc de Perrot,8 Vivek Rao,9 David Grant,10 Graham Roche-Nagle,11 Sean P Cleary,12 Stefan OP Hofer,13 Ralph Gilbert,14 Duminda Wijeysundera,1,3 Paul Ritvo,15 Tahir Janmohamed,16 Gerald O’Leary,1,3 Hance Clarke1,3 1Department of Anesthesia and Pain Management, Toronto General Hospital, University Health Network, University of Toronto, 2Department of Psychology, York University, 3Department of Anesthesia, University of Toronto, 4Palliative Care, University Health Network, University of Toronto, 5Princess Margaret Cancer Centre, University Health Network, University of Toronto, 6Faculty of Kinesiology and Physical Education, University of Toronto, 7Department of Family and Community Medicine, University of Toronto, 8Division of Thoracic Surgery, Toronto General Hospital, 9Division of Cardiovascular Surgery, Toronto General Hospital, 10Multiorgan Transplant Program, Toronto General Hospital, 11Division of Vascular Surgery, Toronto General Hospital, 12Division of General Surgery, Toronto General Hospital, 13Division of Plastic Surgery, Toronto General Hospital, 14Division of Otolaryngology – Head and Neck Surgery, Toronto General Hospital, 15Department of Kinesiology and Health Science, York University, 16ManagingLife, Toronto, ON, CanadaAbstract: Chronic postsurgical pain (CPSP, an often unanticipated result of necessary and even life-saving procedures, develops in 5–10% of patients one-year after major surgery. Substantial advances have been made in identifying patients at elevated risk of developing CPSP based on perioperative pain, opioid use, and negative affect, including depression, anxiety, pain catastrophizing, and posttraumatic stress disorder-like symptoms. The Transitional Pain Service (TPS at

  13. A review of the genus Serangium Blackburn (Coleoptera, Coccinellidae from China

    Directory of Open Access Journals (Sweden)

    Xingmin Wang

    2011-10-01

    Full Text Available The genus Serangium Blackburn from China is reviewed. The genus Catanella Miyatake is removed from synonymy with Serangium. S. baculum Xiao is transferred to Catanella, as C. baculum (Xiao, comb. n. Twelve species of Serangium are described, keyed and illustrated, including eight new species, S. magnipunctatum Wang & Ren, sp. n., S. trimaculatum Wang & Ren, sp. n., S. centrale Wang & Ren, sp. n., S. leigongicus Wang & Ren, sp. n., S. latilobum Wang & Ren, sp. n., S. digitiforme Wang & Ren, sp. n., S. dulongjiang Wang, Ren & Chen, sp. n., and S. contortum Wang & Ren, sp. n. S. punctum Miyatake is newly recorded from China.

  14. The NCAN gene: schizophrenia susceptibility and cognitive dysfunction

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    Wang P

    2016-11-01

    Full Text Available Peirong Wang,1 Jun Cai,2 Jianliang Ni,1 Jiangtao Zhang,1 Wei Tang,3 Chen Zhang2 1Department of Psychiatry, Tongde Hospital of Zhejiang Province, Hangzhou, Zhejiang, 2Schizophrenia Program, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, 3Wenzhou Kangning Hospital, Wenzhou, Zhejiang, People’s Republic of China Background: Cognitive dysfunction has been recognized as a cardinal feature of schizophrenia. Elucidating the neurobiological substrates of cognitive dysfunction in schizophrenia would help identify the underlying mechanism of this disorder. The rs1064395 single nucleotide polymorphism, within the gene encoding neurocan (NCAN, is reported to be associated with schizophrenia in European populations and may influence brain structure in patients with schizophrenia.Methods: In this study, we aimed to explore whether NCAN rs1064395 confers some risk for schizophrenia and cognitive dysfunction in Han Chinese. We recruited 681 patients with schizophrenia and 699 healthy subjects. Two hundred and fifty-four patients were evaluated according to Repeatable Battery for the Assessment of Neuropsychological Status (RBANS.Results: There were no significant differences in genotype or allele distributions of the rs1064395 polymorphism between the schizophrenia and control groups. Patients showed significantly poorer performance than controls on immediate memory, visuospatial skill, language, attention, delayed memory, and total RBANS score. Patients with the A/A or A/G genotype of rs1064395 had lower scores of immediate memory, visuospatial skill, attention, and total RBANS score than those with the G/G genotype. We performed an expression quantitative trait loci analysis and observed a significant association between rs1064395 and NCAN expression in the frontal (P=0.0022, P=0.022 after Bonferroni correction and cerebellar cortex (P=0.0032, P=0.032 after Bonferroni correction.Conclusion: Our findings indicate

  15. Comparison of dynamic contrast-enhanced magnetic resonance imaging with T2-weighted imaging for preoperative staging of early endometrial carcinoma

    Directory of Open Access Journals (Sweden)

    Zheng L

    2015-07-01

    Full Text Available Linfeng Zheng,1,2 Sujuan Zheng,3 Xiaochun Yuan,1 Xifu Wang,1 Zhuoli Zhang,2 Guixiang Zhang1 1Department of Radiology, Shanghai First People’s Hospital, Shanghai Jiao Tong University, Shanghai, People’s Republic of China; 2Department of Radiology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA; 3Department of Obstetrics and Gynecology, Dengfeng People’s Hospital, Zhengzhou, People’s Republic of China Purpose: This study aimed to compare dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI with T2-weighted imaging (T2WI for the preoperative staging of early endometrial carcinoma. Methods: This retrospective study included 22 subjects with early endometrial carcinoma who underwent 3.0 T MRI examination prior to hysterectomy. DCE-MRI and T2WI were evaluated for the preoperative staging of endometrial carcinoma. The sensitivity, specificity, positive predictive value (PPV, negative predictive value (NPV, and accuracy of DCE-MRI and T2WI were assessed and compared using the revised International Federation of Gynecology and Obstetrics surgical staging guidelines (2009 as the reference standard. Results: Out of the 22 cases of endometrial carcinoma, the use of the reference standard method led to the staging of 14 as IA and eight as IB. The sensitivity, specificity, PPV, NPV, and accuracy of DCE-MRI for preoperative staging were 100% (95% confidence interval: 0.73–1.0, 62.5% (95% CI: 0.26–0.90, 82.4% (95% CI: 0.56–0.95, 100% (95% CI: 0.46–1.0, and 86.4%, respectively, and these values were 85.7% (95% CI: 0.56–0.97, 75% (95% CI: 0.36–0.96, 85.7% (95% CI: 0.56–0.97, 75% (95% CI: 0.36–0.96, and 81.8%, respectively, for T2WI. Thus, the sensitivity and accuracy of DCE-MRI were greater than those of T2WI for preoperative endometrial carcinoma staging. Conclusion: DCE-MRI was more sensitive but less specific than T2WI for the preoperative staging of early endometrial carcinoma. DCE-MRI may serve as a

  16. Expression of Notch 1 receptor associated with tumor aggressiveness in papillary thyroid carcinoma

    Directory of Open Access Journals (Sweden)

    Fu H

    2016-03-01

    Full Text Available Hongliang Fu,1 Chao Ma,1 Wenbin Guan,2 Weiwei Cheng,1 Fang Feng,1 Hui Wang1 1Department of Nuclear Medicine, 2Department of Pathology, Xin Hua Hospital, Shanghai Jiao Tong University, School of Medicine, Shanghai, People’s Republic of China Aim: The aim of this study was to assess if the expression of Notch 1 receptor is associated with tumor aggressiveness in papillary thyroid carcinomas (PTCs.Patients and methods: By searching the electronic medical record system of Xin Hua Hospital, all cases of PTC patients who underwent thyroidectomy in the hospital between 2013 and 2014 were retrieved. Then, the cases of patients who had a history of any other malignancy or whose thyroid tumor specimen was not available for assay were rejected. Finally, 68 cases of PTC patients were obtained. Formalin-fixed paraffin-embedded tissue blocks of these patients were studied by immunohistochemistry to learn the expression of Notch 1 receptor. Meanwhile, the clinical data of these patients including sex, age, size of the tumor, presence of node metastasis or distant metastasis, and presence of capsule invasion and tumor multicentricity were collected. Pearson’s chi-square test or Fisher’s exact test was used for measuring statistical differences in categorical variables. All the statistical tests were two-sided. A P-value <0.05 was considered to be statistically significant.Results: A total of 19 male and 49 female PTC patients with a mean age of 44.8±13.6 years (range 18–78 years were studied. Notch 1 receptor expression was found in 15/68 (22% samples of PTC. The expression of Notch 1 receptor was significantly associated with tumor size (P=0.021, distant metastasis (P=0.008, capsule invasion (P=0.001, tumor multicentricity (P=0.018, and age (P=0.033. However, the expression of Notch 1 receptor was not significantly correlated with node metastasis (P=0.096 and sex (P=0.901.Conclusion: The expression of Notch 1 receptor is associated with tumor

  17. Pattern of cerebral hyperperfusion in Alzheimer's disease and amnestic mild cognitive impairment using voxel-based analysis of 3D arterial spin-labeling imaging: initial experience

    Directory of Open Access Journals (Sweden)

    Ding B

    2014-03-01

    Full Text Available Bei Ding,1 Hua-wei Ling,1 Yong Zhang,2 Juan Huang,1 Huan Zhang,1 Tao Wang,3 Fu Hua Yan11Department of Radiology, Ruijin Hospital, School of Medicine, Shanghai Jiao Tong University, 2Applied Science Laboratory, GE Healthcare, 3Department of Gerontology, Shanghai Mental Health Center, Shanghai, People's Republic of ChinaPurpose: A three-dimensional (3D continuous pulse arterial spin labeling (ASL technique was used to investigate cerebral blood flow (CBF changes in patients with Alzheimer's disease (AD, amnestic mild cognitive impairment (aMCI, and age- and sex-matched healthy controls.Materials and methods: Three groups were recruited for comparison, 24 AD patients, 17 MCI patients, and 21 age- and sex-matched control subjects. Three-dimensional ASL scans covering the entire brain were acquired with a 3.0 T magnetic resonance scanner. Spatial processing was performed with statistical parametric mapping 8. A second-level one-way analysis of variance analysis (threshold at P<0.05 was performed on the preprocessed ASL data. An average whole-brain CBF for each subject was also included as group-level covariates for the perfusion data, to control for individual CBF variations.Results: Significantly increased CBF was detected in bilateral frontal lobes and right temporal subgyral regions in aMCI compared with controls. When comparing AD with aMCI, the major hyperperfusion regions were the right limbic lobe and basal ganglia regions, including the putamen, caudate, lentiform nucleus, and thalamus, and hypoperfusion was found in the left medial frontal lobe, parietal cortex, the right middle temporo-occipital lobe, and particularly, the left anterior cingulate gyrus. We also found decreased CBF in the bilateral temporo-parieto-occipital cortices and left limbic lobe in AD patients, relative to the control group. aMCI subjects showed decreased blood flow in the left occipital lobe, bilateral inferior temporal cortex, and right middle temporal cortex

  18. Epigenomic analysis of lung adenocarcinoma reveals novel DNA methylation patterns associated with smoking

    Directory of Open Access Journals (Sweden)

    Tan Q

    2013-10-01

    Full Text Available Qiang Tan,1,* Guan Wang,1,* Jia Huang,1 Zhengping Ding,1 Qingquan Luo,1 Tony Mok,2 Qian Tao,2 Shun Lu1 1Department of Shanghai Lung Cancer Center, Shanghai Chest Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, People's Republic of China; 2Cancer Epigenetics Laboratory, Department of Clinical Oncology, State Key Laboratory of Oncology in South China, Sir YK Pao Center for Cancer and Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong *These authors contributed equally to this paper Abstract: The importance of epigenetic regulation has been increasingly recognized in the development of cancer. In this study, we investigated the impact of smoking, a major risk factor of lung cancer, on DNA methylation by comparing the genome-wide DNA methylation patterns between lung adenocarcinoma samples from six smokers and six nonsmokers. We identified that smoking-induced DNA methylations were enriched in the calcium signaling and neuroactive ligand receptor signaling pathways, which are closely related to smoking-induced lung cancers. Interestingly, we discovered that two genes in the mitogen-activated protein kinase signaling pathway (RPS6KA3 and ARAF were hypomethylated in smokers but not in nonsmokers. In addition, we found that the smoking-induced lung cancer-specific DNA methylations were mostly enriched in nuclear activities, including regulation of gene expression and chromatin remodeling. Moreover, the smoking-induced hypermethylation could only be seen in lung adenocarcinoma tissue but not in adjacent normal lung tissue. We also used differentially methylated DNA loci to construct a diagnostic model to distinguish smoking-associated lung cancer from nonsmoking lung cancer with a sensitivity of 88.9% and specificity of 83.2%. Our results provided novel evidence to support that smoking can cause dramatic changes in the DNA methylation landscape of lung cancer, suggesting that epigenetic

  19. The prevalence and prognostic significance of KRAS mutation subtypes in lung adenocarcinomas from Chinese populations

    Directory of Open Access Journals (Sweden)

    Zheng DF

    2016-02-01

    Full Text Available Difan Zheng,1,2,* Rui Wang,1,2,* Yang Zhang,1,2 Yunjian Pan,1,2 Xinghua Cheng,3 Chao Cheng,1,2 Shanbo Zheng,1,2 Hang Li,1,2 Ranxia Gong,1,2 Yuan Li,2,4 Xuxia Shen,2,4 Yihua Sun,1,2 Haiquan Chen1–3,51Department of Thoracic Surgery, Fudan University Shanghai Cancer Center, 2Department of Oncology, Shanghai Medical College, Fudan University, 3Shanghai Chest Hospital, Shanghai Jiao Tong University, 4Department of Pathology, Fudan University Shanghai Cancer Center, 5Institutes of Biomedical Sciences, Fudan University, Shanghai, People’s Republic of China*These authors contributed equally to this workBackground: We performed this retrospective study to identify the prevalence of KRAS mutation in Chinese populations and make a comprehensive investigation of the clinicopathological features of KRAS mutation in these patients.Patients and methods: Patients from 2007 to 2013 diagnosed with primary lung adenocarcinoma who received a radical resection were examined for KRAS, EGFR, HER2, BRAF mutations, and ALK, RET, and ROS1 fusions. Clinicopathological features, including sex, age, tumor–lymph node–metastasis stage, tumor differentiation, smoking status, histological subtypes, and survival information were analyzed.Result: KRAS mutation was detected in 113 of 1,368 patients. Nine different subtypes of KRAS mutation were identified in codon 12, codon 13, and codon 61. KRAS mutation was more frequently found in male patients and former/current smoker patients. Tumors with KRAS mutation had poorer differentiation. Invasive mucinous adenocarcinoma predominant and solid predominant subtypes were more frequent in KRAS mutant patients. No statistical significance was found in relapse-free survival or overall survival between patients with KRAS mutation and patients with other mutations.Conclusion: In Chinese populations, we identified KRAS mutation in 8.3% (113/1,368 of the patients with lung adenocarcinoma. KRAS mutation defines a molecular subset of

  20. Photoelectron Spectroscopy Study of [Ta2B6]-: a Hexagonal Bipyramdial Cluster

    Science.gov (United States)

    Jian, Tian; Li, Weili; Romanescu, Constantin; Wang, Lai-Sheng

    2014-06-01

    It has been a long-sought goal in cluster science to discover stable atomic clusters as building blocks for cluster-assembled nanomaterials, as exemplified by the fullerenes and their subsequent bulk syntheses.[1,2] Clusters have also been considered as models to understand bulk properties, providing a bridge between molecular and solid-state chemistry.[3] Herein we report a joint photoelectron spectroscopy and theoretical study on the [Ta2B6]- and [Ta2B6] clusters.[4] The photoelectron spectrum of [Ta2B6]- displays a simple spectral pattern and a large HOMO-LUMO gap, suggesting its high symmetry. Theoretical calculations show that both the neutral and anion are D6h pyramidal. The chemical bonding analyses for [Ta2B6] revealed the nature of the B6 and Ta interactions and uncovered strong covalent bonding between B6 and Ta. The D6h-[TaB6Ta] gaseous cluster is reminiscent of the structural pattern in the ReB6X6Re core in the [(Cp*Re)2B6H4Cl2] and the TiB6Ti motif in the newly synthesized Ti7Rh4Ir2B8 solid-state compound.[5,6] The current work provides an intrinsic link between a gaseous cluster and motifs for solid materials. Continued investigations of the transition-metal boron clusters may lead to the discovery of new structural motifs involving pure boron clusters for the design of novel boride materials. Reference [1] H.W. Kroto, J. R. Heath, S. C. OBrien, R. F. Curl, R. E. Smalley, Nature 1985, 318, 162 - 163. [2] W. Krtschmer, L. D. Lamb, K. Fostiropoulos, D. R. Huffman, Nature 1990, 347, 354 - 358. [3] T. P. Fehlner, J.-F. Halet, J.-Y. Saillard, Molecular Clusters: A Bridge to Solid-State Chemitry, Cambridge University Press, UK, 2007. [4] W. L. Li, L. Xie, T. Jian, C. Romanescu, X. Huang, L.-S. Wang, Angew. Chem. Int. Ed. 2014, 126, 1312 - 1316. [5] B. Le Guennic, H. Jiao, S. Kahlal, J.-Y. Saillard, J.-F. Halet, S. Ghosh, M. Shang, A. M. Beatty, A. L. Rheingold, T. P. Fehlner, J. Am. Chem. Soc. 2004, 126, 3203 - 3217. [6] B. P. T. Fokwa, M. Hermus, Angew

  1. Sex differences in obesity and cognitive function in a cognitively normal aging Chinese Han population

    Directory of Open Access Journals (Sweden)

    Li W

    2017-09-01

    Full Text Available Wei Li,* Qi Qiu,* Lin Sun, Ling Yue, Tao Wang, Xia Li, Shifu Xiao Alzheimer’s Disease and Related Disorders Center, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, People’s Republic of China *These authors contributed equally to this work Background: Sex differences in Alzheimer’s disease and mild cognitive impairment have been well recognized. However, sex differences in cognitive function and obesity in cognitively normal aging Chinese Han population have not attracted much attention. Objective: The aim of this study was to investigate the relationship between sex, obesity, and cognitive function in an elderly Chinese population with normal cognitive function. Subjects and methods: A total of 228 cognitively normal aging participants (males/females =93/135 entered this study. Their general demographic information (sex, age, and education was collected by standardized questionnaire. Apolipoprotein E (APOE genotype and serum lipid levels were measured. The Montreal Cognitive Assessment (MoCA was used to assess participants’ cognitive function. Results: The prevalence of obesity in elderly women (18/133, 13.5% was significantly higher than that in men (5/92, 5.4%, P=0.009. Regression analyses showed that obesity was associated with drinking alcohol (OR =13.695, P=0.045 and triglyceride (OR =1.436, P=0.048 in women and limited to low-density lipoprotein (OR =11.829, P=0.023 in men. Women performed worse on the naming score for MoCA than men (P<0.01. Stepwise linear regression analysis showed that education (t=3.689, P<0.001 and smoking (t=2.031, P=0.045 were related to the score of naming in female, while high-density lipoprotein (t=–2.077, P=0.041 was related to the score of naming in male; however, no correlation was found between body mass index and cognitive function in both male and female (P>0.05. Conclusion: Our finding suggests that there are significant sex differences in obesity and

  2. The efficiency and safety of trastuzumab and lapatinib added to neoadjuvant chemotherapy in Her2-positive breast cancer patients: a randomized meta-analysis

    Directory of Open Access Journals (Sweden)

    Chen ZL

    2016-05-01

    Full Text Available Zhe-Ling Chen, Yan-Wei Shen, Shu-Ting Li, Chun-Li Li, Ling-Xiao Zhang, Jiao Yang, Meng Lv, Ya-Yun Lin, Xin Wang, Jin Yang Department of Medical Oncology, The First Affiliated Hospital of Xi’an Jiaotong University, Xi’an, Shaanxi, People’s Republic of China Background: The addition of human epidermal growth factor receptor 2 (Her2 therapies to neoadjuvant chemotherapy (NAC during treatment of Her2-positive breast cancer has been proposed as an effective way to improve the prognosis. However, the treatment outcomes of adding trastuzumab, lapatinib, or both to NAC were not unequivocal in randomized clinical trials. Based on these data, a meta-analysis was performed. Objective: The main objective was to evaluate the efficiency and safety of trastuzumab and lapatinib added to NAC for treatment of Her2-positive breast cancer. Methods: ClinicalTrials.gov and PubMed were searched for randomized clinical trials that compared trastuzumab, lapatinib, or both, added to NAC. The main endpoint was a pathologically complete response (pCR rate, in breast only or in breast and lymph nodes. The drug safety and the influence of hormone-receptor status, comparing the clinical response and the rate of breast conservation, were evaluated. Results: A total of eight publications were included in the primary analysis, designed as two or three subgroups. The cumulative cases were 2,349 and the analyses of all the clinical trials showed that the pCR rate was significantly higher in the group receiving trastuzumab than that in the group with lapatinib, either in breast only (P=0.001 or in breast and lymph nodes (P=0.0001. Similar results could be seen in comparisons of the combination versus trastuzumab group. Further studies of subgroups divided into hormone receptor-positive or-negative patients showed that the addition of trastuzumab or dual Her2-targeted therapy significantly improved the pCR rate in patients who were hormone-insensitive. Regarding the toxic

  3. Taxonomic review on the subgenus Tripodura Townes (Diptera: Chironomidae: Polypedilum) from China with eleven new species and a supplementary world checklist.

    Science.gov (United States)

    Zhang, Ruilei; Song, Chao; Qi, Xin; Wang, Xinhua

    2016-07-05

    The subgenus Tripodura Townes of Polypedilum Kieffer from China including 26 species is reviewed. Eleven new species, named P. (T.) absensilobum Zhang & Wang sp. n., P. (T.) apiculusetosum Zhang & Wang sp. n., P. (T.) arcuatum Zhang & Wang sp. n., P. (T.) bilamella Zhang & Wang sp. n., P. (T.) conghuaense Zhang & Wang sp. n., P. (T.) dengae Zhang & Wang sp. n., P. (T.) mengmanense Zhang & Wang sp. n., P. (T.) napahaiense Zhang & Wang sp. n., P. (T.) parallelum Zhang & Wang sp. n., P. (T.) pollicium Zhang & Wang sp. n. and P. (T.) trapezium Zhang & Wang sp. n. are described and illustrated based on male imagines. Three species, P. (T.) quadriguttatum Kieffer, P. (T.) unifascia (Tokunaga) and P. (T.) udominutum Niitsuma are firstly recorded in China. A key to known male imagines of Chinese species and an updated world checklist of subgenus Tripodura are presented.

  4. -Stability Approach to Variational Iteration Method for Solving Integral Equations

    Directory of Open Access Journals (Sweden)

    Rhoades BE

    2009-01-01

    Full Text Available We consider -stability definition according to Y. Qing and B. E. Rhoades (2008 and we show that the variational iteration method for solving integral equations is -stable. Finally, we present some text examples to illustrate our result.

  5. Shantang: Charitable Temples in China, Singapore, and Malaysia

    National Research Council Canada - National Science Library

    Tan Chee-Beng

    2012-01-01

    .... Unlike the shantangs as benevolent societies in late Ming and Qing China, the shantangs described in this article not only emphasize charitable activities, they are also temples that honor Song Dafeng as a deity...

  6. Uniqueness of singular solution of semilinear elliptic equation

    Indian Academy of Sciences (India)

    Author Affiliations. Baishun Lai1 2 Qing Luo2. Institute of Contemporary Mathematics, Henan University, Kaifeng 475004, People's Republic of China; School of Mathematics and Information Science, Henan University, Kaifeng 475004, People's Republic of China ...

  7. Download this PDF file

    African Journals Online (AJOL)

    AJTCAM

    Bing Wang1, 2#, Wen Wang1#, Feng Li1#, Zongren Wang1, Jing Ma1*, Gang Zhao2* .... Altra II flow cytometer (Beckman, Los Angles, CA, USA) (Wang et al., 2011b). ..... pathway in brain fat mass- and obesity-associated (FTO) downregulation.

  8. The genus Microserangium Miyatake (Coleoptera, Coccinellidae) from China.

    Science.gov (United States)

    Wang, Xingmin; Slipiński, Adam; Ren, Shunxiang

    2013-01-01

    The genus Microserangium Chapinfrom China is reviewed. Nine species are recognized, including seven new species: M. erythrinum Wang & Ren, sp. n., M. fuscum Wang & Ren, sp. n., M. glossoides Wang & Ren, sp. n., M. shennongensis Wang & Ren, sp. n., M. semilunatum Wang & Ren, sp. n., M. deltoides Wang & Ren, sp. n., M. dactylicum Wang & Ren, sp. n. Male genitalia of M. hainanensis Miyatake, 1961 are described for the first time. All species are described and illustrated. A key and distribution map to the known species from China are given.

  9. The genus Microserangium Miyatake (Coleoptera, Coccinellidae from China

    Directory of Open Access Journals (Sweden)

    Xingmin Wang

    2013-12-01

    Full Text Available The genus Microserangium Chapin from China is reviewed. Nine species are recognized, including seven new species: M. erythrinum Wang & Ren, sp. n., M. fuscum Wang & Ren, sp. n., M. glossoides Wang & Ren, sp. n., M. shennongensis Wang & Ren, sp. n., M. semilunatum Wang & Ren, sp. n., M. deltoides Wang & Ren, sp. n., M. dactylicum Wang & Ren, sp. n. Male genitalia of M. hainanensis Miyatake, 1961 are described for the first time. All species are described and illustrated. A key and distribution map to the known species from China are given.

  10. Differences in reporting of maternal and child health indicators: A comparison between routine and survey data in Guizhou Province, China

    Directory of Open Access Journals (Sweden)

    Du Q

    2012-07-01

    Full Text Available Qing Du,1,2 Øyvind Næss,1,3 Espen Bjertness,1,4 Gonghuan Yang,5 Linhong Wang,6 Bernadette Nirmal Kumar71Institute of Health and Society, University of Oslo, Oslo, Norway; 2Binzhou Medical College, Yantai, China; 3The Norwegian Institute of Public Health, Oslo, Norway; 4Tibet University Medical College, Lhasa, China; 5Chinese Center for Disease Control and Prevention, Beijing, China; 6National Center for Women and Children's Health, Chinese Center for Disease Control and Prevention, Beijing, China; 7Norwegian Center for Minority Health Research, Oslo, NorwayBackground: The quality of routine data, such as the maternal mortality ratio (MMR, infant mortality rate (IMR, and under-five mortality rate (U5MR is often questioned. The objective of this study was to compare routine and survey data on key maternal and child health indicators, including the MMR, IMR, and U5MR in the Guizhou Province of China.Methods: In 2008, an urban area and a rural area in the Guizhou Province were randomly selected. All households in the selected areas were included and, of the total 5466 households therein, 5459 were visited. The response rate was 99.9%. Survey data were collected from mothers (46.0%, fathers (32.5%, grandmothers (11.1%, grandfathers (9.0%, and other caregivers (1.4%. Data from routine records of the health bureaus in selected areas were reviewed for the same indicators. The Chi-square test was used to study the differences between routine data and survey data.Results: We found the differences between the routine and survey data live births in the survey data (68 was fewer than in the routine data (94 in the rural area, while live births in the survey data (106 was larger than in the routine data (96 in the urban area. The IMR was higher in the survey data (51.7 per thousand as compared with routine data (31.6 per thousand. The U5MR was higher (69.0 per thousand in the survey data than in the routine data (42.1 per thousand. Indicators related to the

  11. CHADS2 score has a better predictive value than CHA2DS2-VASc score in elderly patients with atrial fibrillation

    Directory of Open Access Journals (Sweden)

    Xing YL

    2016-07-01

    Full Text Available Yunli Xing, Qing Ma, Xiaoying Ma, Cuiying Wang, Dai Zhang, Ying Sun Department of Geriatrics and Gerontology, Beijing Friendship Hospital, Capital Medical University, Beijing, People’s Republic of China Aim: The study aims to compare the ability of CHA2DS2-VASc (defined as congestive heart failure, hypertension, age ≥75 years [two scores], type 2 diabetes mellitus, previous stroke, transient ischemic attack, or thromboembolism [TE] [doubled], vascular disease, age 65–74 years, and sex category and CHADS2 (defined as congestive heart failure, hypertension, age ≥75 years, type 2 diabetes mellitus, previous stroke [doubled] scores to predict the risk of ischemic stroke (IS or TE among patients with nonvalvular atrial fibrillation (NVAF.Methods: A total of 413 patients with NVAF aged ≥65 years, and not on oral anticoagulants for the previous 6 months, were enrolled in the study. The predictive value of the CHA2DS2-VASc and CHADS2 scores for IS/TE events was evaluated by the Kaplan–Meier method.Results: During a follow-up period of 1.99±1.29 years, 104 (25.2% patients died and 59 (14.3% patients developed IS/TE. The CHADS2 score performed better than the CHA2DS2-VASc score in predicting IS/TE as assessed by c-indexes (0.647 vs 0.615, respectively; P<0.05. Non-CHADS2 risk factors, such as vascular disease and female sex, were not found to be predictive of IS/TE (hazard ratio 1.518, 95% CI: 0.832–2.771; hazard ratio 1.067, 95% CI: 0.599–1.899, respectively. No differences in event rates were found in patients with the CHADS2 scores of 1 and 2 (7.1% vs 7.8%. It was observed that patients with a CHADS2 score of ≥3 were most in need of anticoagulation therapy.Conclusion: In patients with NVAF aged ≥65 years, the CHADS2 score was found to be significantly better in predicting IS/TE events when compared to the CHA2DS2-VASc score. Patients with a CHADS2 score of ≥3 were associated with high risk of IS/TE events. Keywords: NVAF

  12. Effects of paroxetine-mediated inhibition of GRK2 expression on depression and cardiovascular function in patients with myocardial infarction

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    Tian XQ

    2016-09-01

    Full Text Available Xiuqing Tian,1 Qing Wang,1 Rui Guo,2 Lingling Xu,3 Qin M Chen,4 Yinglong Hou1 1Department of Cardiology, Qianfoshan Hospital of Shandong University, Jinan City, 2Department of Physiology, Nanjing University of Chinese Medicine, Nanjing City, 3College of Medicine, Weifang Medical University, Weifang City, People’s Republic of China; 4Department of Pharmacology, College of Medicine, University of Arizona, Tucson, AZ, USA Background: Paroxetine is a selective serotonin reuptake inhibitor utilized in the treatment of depression and anxiety disorders. Recent studies have identified paroxetine as a G protein-coupled receptor kinase-2 (GRK2 inhibitor capable of reversing cardiac dysfunction and remodeling in experimental models of acute myocardial infarction (AMI. We determine the clinical importance of paroxetine on cardiac functions in patients having AMI with depression (AMID in comparison with fluoxetine, an unrelated selective serotonin reuptake inhibitor that does not inhibit GRK2.Methods: Diagnosis of depression was based on the 17-item Hamilton Depression Scale and Self-rating Depression Scale in AMI patients after hospital admission. AMID patients were randomly assigned to paroxetine or fluoxetine for treatment of depression. Heart rate variability and cardiac function were evaluated. GRK2 protein levels were measured using peripheral lymphocytes and Western blot.Results: GRK2 expression in AMID patients was significantly higher than that in AMI patients without depression. In AMID patients, GRK2 levels were positively correlated with the 17-item Hamilton Depression Scale and the Self-rating Depression Scale scores, and negatively correlated with heart rate variability. Treatment of AMID patients with paroxetine significantly reduced the expression of GRK2, normalized the autonomic nervous system function, and improved cardiac performance. In contrast, fluoxetine normalized the autonomic nervous system but did not reduce the expression of

  13. Combination of cetuximab and PP242 synergistically suppress the progression of wild-type KRAS colorectal carcinoma

    Directory of Open Access Journals (Sweden)

    Cheng L

    2015-11-01

    Full Text Available Lei Cheng,1,* Zuguang Xia,2,3,* Xinyu Bian,1 Guangchao Li,4 Jing Hu,1 Ya Cao,5 Qing Wang,1 Xiaoping Qian1 1Comprehensive Cancer Center of Drum-Tower Hospital, Medical School of Nanjing University, Clinical Cancer Institute of Nanjing University, Nanjing, 2Department of Medical Oncology, Fudan University Shanghai Cancer Center, Shanghai, 3Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, 4School of Bioscience and Bioengineering, South China University of Technology, Guangzhou, Guangdong, 5Department of Biological Science and Technology and State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing, People’s Republic of China *These authors contributed equally to this work Abstract: Mammalian target of rapamycin (mTOR has been shown to be overactive in human colorectal cancer, but the first-generation mTOR inhibitor, rapamycin, has failed to show clinical efficacy against colorectal cancer. On the other hand, although the second-generation mTOR inhibitor, PP242, has exerted substantial efficacy, it was revealed that independent inhibition by PP242 was transient, which could lead to positive-feedback loop to EGFR. Using wild-type KRAS colorectal cancer cells as models, we investigate the treatment efficacy of a widely used anti-EGFR monoclonal antibody, cetuximab, and PP242, alone or in combination in vitro and in vivo. Results of cell viability assays confirmed the synergistic inhibitory effect of PP242 and cetuximab on the survival of Caco-2 and HT-29 cells. Moreover, the ability of cancer-cell invasion and proliferation was also significantly inhibited by the combination therapy when compared with cetuximab or PP242 alone. Interestingly, the percentage of CD44-positive cancer cells was substantially decreased by the combination therapy in comparison with PP242 alone through fluorescence-activated cell sorting. The growth of cancer stem-like cell spheres in vitro was

  14. Efficacy of goniosynechialysis for advanced chronic angle-closure glaucoma

    Directory of Open Access Journals (Sweden)

    Qing G

    2012-10-01

    Full Text Available Guoping Qing,1,2 Ningli Wang,1 Dapeng Mu11Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology and Visual Sciences Key Lab, Beijing, China; 2State Key Laboratory of Brain and Cognitive Science, Institute of Biophysics, Chinese Academy of Sciences, Beijing, ChinaPurpose: To evaluate the intraocular pressure (IOP-lowering efficacy of goniosynechialysis (GSL for advanced chronic angle-closure glaucoma (CACG using a simplified slit-lamp technique.Patients and methods: Patients with CACG with one severely affected eye with best-corrected visual acuity below 20/200 and a mildly or functionally unaffected fellow eye were enrolled in this study. All patients underwent ophthalmologic examinations including measurement of visual acuity, best-corrected visual acuity, and IOP; biomicroscopy; specular microscopy; fundus examination; and gonioscopy followed by anterior chamber paracentesis and GSL for nasal peripheral anterior synechiae in the eye with severe CACG.Results: Thirty patients (18 men, 12 women were identified as having CACG with an initial mean IOP of 47.1 ± 6.7 mmHg (range 39–61 mmHg in the severely affected eye. One week after GSL, the mean IOP of the treated eyes decreased to 19.3 ± 2.8 mmHg (range 14–26 mmHg without antiglaucoma medication (average decrease 27.7 ± 6.5 mmHg; range 16–41 mmHg, which was significant (P < 0.00001 compared with baseline. After an average follow-up period of 36.6 ± 1.0 months (range 35–38 months, the mean IOP stabilized at 17.4 ± 2.2 mmHg (range 12–21 mmHg. The nasal angle recess did not close again in any one of the patients during the follow-up period. The average significant (P < 0.00001 decrease in corneal endothelial cell density in the treated eyes was 260 ± 183 cells/mm2 (range 191–328 cells/mm2.Conclusions: Anterior chamber paracentesis and GSL lowers IOP in advanced CACG, though it may lead to mild corneal endothelial cell loss

  15. Comparing the ability of cognitive and affective Theory of Mind in adolescent onset schizophrenia

    Directory of Open Access Journals (Sweden)

    Li D

    2017-03-01

    Full Text Available Dandan Li,1,2,* Xiaosi Li,3,* Fengqiong Yu,1,2 Xingui Chen,2,4 Long Zhang,2,4 Dan Li,2,4 Qiang Wei,2,4 Qing Zhang,1,2 Chunyan Zhu,1,2 Kai Wang1,2,4 1Department of Medical Psychology, Anhui Medical University, Hefei, 2Collaborative Innovation Centre of Neuropsychiatric Disorders and Mental Health, Anhui Province, 3Mental Health Center of Anhui Province, 4Department of Neurology, The First Affiliated Hospital of Anhui Medical University, Hefei, China *These authors contributed equally to this work Background: Evidence in the literature suggests that there is an impairment of social cognition in schizophrenia. Theory of Mind (ToM is defined as one’s ability to understand others’ wishes, beliefs, intentions, and other psychological states and thereby to judge others’ behavior, as an essential component of social cognition. However, there have been limited studies on social cognition, especially ToM in adolescent onset schizophrenia (AOS. The current study aims to investigate ToM abilities in adolescent schizophrenia according to various ToM subcomponents (cognitive ToM and affective ToM and various ToM orders (first order and second order.Methods: This study examines ToM in 35 adolescent schizophrenic patients and 35 healthy adolescents using the “Yoni task” and “Faux Pas Recognition test” to assess their affective and cognitive ToM abilities.Results: In the Yoni task, patients with AOS showed differences in ToM abilities either on a different order or under different conditions. The Faux Pas Recognition task results revealed that AOS patients were not always able to recognize a faux pas or understand complicated emotions under the faux pas scenario. Furthermore, as indicated by the correlation analysis, neither cognitive ToM nor affective ToM was related to the patients’ symptoms, disease duration, dose of medication, or intelligence quotient (IQ.Conclusion: Our findings showed AOS impairment in the performance of ToM tasks. It

  16. Obstructive sleep apnea and endothelial progenitor cells

    Directory of Open Access Journals (Sweden)

    Wang Q

    2013-10-01

    Full Text Available Qing Wang,1,* Qi Wu,2,* Jing Feng,3,4 Xin Sun5 1The Second Respiratory Department of the First People's Hospital of Kunming, Yunnan, People's Republic of China; 2Tianjin Haihe Hospital, Tianjin, People's Republic of China; 3Respiratory Department of Tianjin Medical University General Hospital, Tianjin, People's Republic of China; 4Division of Pulmonary and Critical Care Medicine, Duke University Medical Center, Durham, NC, USA; 5Respiratory Department of Tianjin Haihe Hospital, Tianjin, People's Republic of China *These authors contributed equally to this work Background: Obstructive sleep apnea (OSA occurs in 4% of middle-aged men and 2% of middle-aged women in the general population, and the prevalence is even higher in specific patient groups. OSA is an independent risk factor for a variety of cardiovascular diseases. Endothelial injury could be the pivotal determinant in the development of cardiovascular pathology in OSA. Endothelial damage ultimately represents a dynamic balance between the magnitude of injury and the capacity for repair. Bone marrow–derived endothelial progenitor cells (EPCs within adult peripheral blood present a possible means of vascular maintenance that could home to sites of injury and restore endothelial integrity and normal function. Methods: We summarized pathogenetic mechanisms of OSA and searched for available studies on numbers and functions of EPCs in patients with OSA to explore the potential links between the numbers and functions of EPCs and OSA. In particular, we tried to elucidate the molecular mechanisms of the effects of OSA on EPCs. Conclusion: Intermittent hypoxia cycles and sleep fragmentation are major pathophysiologic characters of OSA. Intermittent hypoxia acts as a trigger of oxidative stress, systemic inflammation, and sympathetic activation. Sleep fragmentation is associated with a burst of sympathetic activation and systemic inflammation. In most studies, a reduction in circulating EPCs has

  17. Simple models based on gamma-glutamyl transpeptidase and platelets for predicting survival in hepatitis B-associated hepatocellular carcinoma

    Directory of Open Access Journals (Sweden)

    Pang Q

    2016-04-01

    Full Text Available Qing Pang, Jian-Bin Bi, Zhi-Xin Wang, Xin-Sen Xu, Kai Qu, Run-Chen Miao, Wei Chen, Yan-Yan Zhou, Chang Liu Department of Hepatobiliary Surgery, the First Affiliated Hospital of Medical College, Xi’an Jiaotong University, Shaanxi Province, People’s Republic of China Background: Several hepatic cirrhosis-derived noninvasive models have been developed to predict the incidence and outcomes of hepatocellular carcinoma (HCC. We aimed to investigate the prognostic significance of the two novel established cirrhosis-associated models based on gamma-glutamyl transpeptidase (GGT and platelets in hepatitis B-associated HCC. Methods: We retrospectively evaluated 182 HCC patients with positive hepatitis B surface antigen who received radical therapy at a single institution between 2002 and 2012. Laboratory data prior to operation were collected to calculate the GGT to platelets ratio (GPR and the S-index. Predictive factors associated with overall survival and recurrence-free survival were assessed using log-rank test and multivariate Cox analysis. Additional analyses were performed after patients were stratified based on cirrhosis status, tumor size, therapy methods, and so forth, to investigate the prognostic significance in different subgroups. Results: During a median follow-up time of 45.0 months, a total of 88 (48.4% patients died and 79 (43.4% patients recurred. The cut-off points for GPR and S-index in predicting death were determined to be 0.76 and 0.56, respectively. Compared with patients with a lower GPR, those with GPR ≥0.76 had a higher probability of cirrhosis and a larger tumor (both P<0.05. GPR and S-index were both found to be significantly associated with survival by univariate log-rank test. Multivariate analysis identified tumor size ≥5 and high level of GPR, but not high Barcelona Clinic Liver Cancer stage or S-index, as independent factors for predicting poor overall survival and recurrence-free survival. Conclusion: The GPR is

  18. Altered spontaneous brain activity pattern in patients with high myopia using amplitude of low-frequency fluctuation: a resting-state fMRI study

    Directory of Open Access Journals (Sweden)

    Huang X

    2016-11-01

    Full Text Available Xin Huang,1,2,* Fu-Qing Zhou,3,* Yu-Xiang Hu,1 Xiao-Xuan Xu,1 Xiong Zhou,4 Yu-Lin Zhong,1 Jun Wang,4 Xiao-Rong Wu1 1Department of Ophthalmology, The First Affiliated Hospital of Nanchang University, Nanchang, 2Department of Ophthalmology, The First People’s Hospital of Jiujiang City, Jiujiang, 3Department of Radiology, The First Affiliated Hospital of Nanchang University, Jiangxi Province Medical Imaging Research Institute, 4Second Department of Respiratory Disease, Jiangxi Provincial People’s Hospital, Nanchang, Jiangxi, People’s Republic of China *These authors contributed equally to this work Objective: Many previous reports have demonstrated significant neural anatomy changes in the brain of high myopic (HM patients, whereas the spontaneous brain activity changes in the HM patients at rest are not well studied. Our objective was to use amplitude of low-frequency fluctuation (ALFF method to investigate the changes in spontaneous brain activity in HM patients and their relationships with clinical features. Methods: A total of 38 patients with HM (17 males and 21 females and 38 healthy controls (HCs (17 males and 21 females closely matched in age, sex, and education underwent resting-state functional magnetic resonance imaging scans. The ALFF method was used to assess local features of spontaneous brain activity. The relationship between the mean ALFF signal values in many brain regions and the clinical features in HM patients was calculated by correlation analysis. Results: Compared with HCs, the HM patients had significantly lower ALFF in the right inferior and middle temporal gyrus, left middle temporal gyrus, left inferior frontal gyrus/putamen, right inferior frontal gyrus/putamen/insula, right middle frontal gyrus, and right inferior parietal lobule and higher ALFF values in the bilateral midcingulate cortex, left postcentral gyrus, and left precuneus/inferior parietal lobule. However, no relationship was found between the mean ALFF

  19. Pepper seed variety identification based on visible/near-infrared spectral technology

    Science.gov (United States)

    Li, Cuiling; Wang, Xiu; Meng, Zhijun; Fan, Pengfei; Cai, Jichen

    2016-11-01

    Pepper is a kind of important fruit vegetable, with the expansion of pepper hybrid planting area, detection of pepper seed purity is especially important. This research used visible/near infrared (VIS/NIR) spectral technology to detect the variety of single pepper seed, and chose hybrid pepper seeds "Zhuo Jiao NO.3", "Zhuo Jiao NO.4" and "Zhuo Jiao NO.5" as research sample. VIS/NIR spectral data of 80 "Zhuo Jiao NO.3", 80 "Zhuo Jiao NO.4" and 80 "Zhuo Jiao NO.5" pepper seeds were collected, and the original spectral data was pretreated with standard normal variable (SNV) transform, first derivative (FD), and Savitzky-Golay (SG) convolution smoothing methods. Principal component analysis (PCA) method was adopted to reduce the dimension of the spectral data and extract principal components, according to the distribution of the first principal component (PC1) along with the second principal component(PC2) in the twodimensional plane, similarly, the distribution of PC1 coupled with the third principal component(PC3), and the distribution of PC2 combined with PC3, distribution areas of three varieties of pepper seeds were divided in each twodimensional plane, and the discriminant accuracy of PCA was tested through observing the distribution area of samples' principal components in validation set. This study combined PCA and linear discriminant analysis (LDA) to identify single pepper seed varieties, results showed that with the FD preprocessing method, the discriminant accuracy of pepper seed varieties was 98% for validation set, it concludes that using VIS/NIR spectral technology is feasible for identification of single pepper seed varieties.

  20. Agama Khonghucu Sejarah, Ajaran, dan Keorganisasiannya di Pontianak Kalimantan Barat

    Directory of Open Access Journals (Sweden)

    Sulaiman Sulaiman

    2009-06-01

    Full Text Available Current confucius religion research is performed at Pontianak, West KalimantanProvince. The research shows that confucius religion characteristics which are moretraditional come from their ancestor’s tradition. The History reveals the beginningof confucius religion invoking from traditional belief, which is Ru Jiao. The prophetKhong Zi has finalized Ru Jiao into Confucius religion. Confucius followers belief inone God, Prophet, and holybook, and belief in forefather. The history of confuciusreligion ever experienced blur period during new regime administration. However,their leader manage to retain their followers through religious organization.Key words : Khonghucu, history, doctrine, organization

  1. Realignments in religion and tensions over identity: Yiguan dao, an example of a “New Religion”

    OpenAIRE

    Micollier, Evelyne

    1998-01-01

    International audience; The restructuring of religious beliefs and practices, and among them, those of “new religions” (xinxing zongjiao) are analysed in terms of tensions over identity in the Taiwanese context. This will be done mainly on the basis of the example of Yiguan dao movement in a comparative perspective, utilising the examples of Tiandi jiao and Xuanyuan jiao. Among the “new religions”, the Yiguan dao (Path of Unity) offers a three-fold interest: firstly, its success—the number of...

  2. Potential Fit to the Department Outweighs Professional Criteria in the Hiring Process in Academic Libraries. A Review of: Wang, Z. & Guarria, C. (2010. Unlocking the mystery: What academic library search committees look for in filling faculty positions. Technical Services Quarterly, 27, 66–86.

    Directory of Open Access Journals (Sweden)

    Yvonne Hultman Özek

    2010-12-01

    Full Text Available Objective – To identify key factors affecting the probability of obtaining an interview and being hired for an academic library position.Design – An online survey was distributed via the following electronic mail lists: ACRL, LITA, COLLIB, METRO, ACQNET, COLLDV, ULS, EQUILIBR, and ALF. The questionnaire was posted via StudentVoice, an assessment survey provider.Setting – Academic libraries in the United States.Subjects – The 242 academic library search committees that responded to the online survey.Methods – The authors reviewed the literature on the hiring process in academic libraries. A questionnaire for an online survey was developed. The instrument contained closed questions with the option to add comments. The survey was available for completion June 3 to June 15, 2008.Main Results – Skills and performance of job requirements were rated as the most important criteria by 90% of the 242 academic library search committees that responded to the survey. Previous academic library experience was rated as essential by 38%. The findings also showed that committees are positive towards hiring recent graduates, and over 90% check references. In addition, 75% of the respondents emphasized the importance of skills in bibliographic instruction (BI, particularly when choosing staff for public services.Furthermore, of the 242 respondents, 47.52%, answering the corresponding question indicated that a relevant cover letter, correct spelling, and declaration of the candidate’s activities over all time periods are crucial aspects.Those in favour of using a weighted scoring system, 37% of 218 respondents, felt that it served as a tool to level the playing field for gathering accurate information, and it also helped to improve the efficiency as well as speed of the hiring process. However, 62.84% of the respondents commented that a weighted scoring system is too prescribed, and some universities did not allow the use of this method. Of 218 respondents, 65% employed evaluation forms after an interview, 38% reported that they would go beyond the applicant’s given references, and 61% felt that the applicant’s potential to fit into the department was important. The “potential fit” criteria scored the highest of these criteria: demonstrated performance of job requirements; cover letter; and knowledge of trends in latest developments in library science (p. 74. Of 211 respondents, 47.39% reported that the average length of the search process was 4 to 6 months. Most respondents perceived the search process as slow.Conclusion – In general, the survey offered an overview of current practices of academic library search committees, which can aid those on the hiring side as well as those who are seeking a job. Based on the results, the authors state that, in addition to all of the job requirements, it is vital to consider the potential fit of the applicant within the department. The hiring of candidates with less experience emphasizes the significance of fitting into the department and can be weighed against selection of individuals with more experience. This conclusion is encouraging for those who have recently graduated from library school.

  3. For Non-expert Clinical Searches, Google Scholar Results are Older with Higher Impact while PubMed Results Offer More Breadth. A Review of: Nourbakhsh, E. F., Nugent, R. F., Wang, H. F., Cevik, C. F., & Nugent, K. (2012. Medical literature searches: A comparison of PubMed and Google Scholar. Health Information and Libraries Journal, 29(3, 214-222.

    Directory of Open Access Journals (Sweden)

    Carol Perryman

    2013-06-01

    Full Text Available Objectives – To compare PubMed and Google Scholar results for content relevance and article qualityDesign – Bibliometric study.Setting – Department of Internal Medicine at Texas Tech University Health Sciences Center.Methods – Four clinical searches were conducted in both PubMed and Google Scholar. Search methods were described as “real world” (p. 216 behaviour, with the searchers familiar with content, though not expert at retrieval techniques. The first 20 results from each search were evaluated forrelevance to the initial question, as well as for quality.Relevance was determined based on one author’s subjective assessment of information in the title and abstract, when available, and then tested by two other authors, with discrepancies discussed and resolved. Items were assigned to one of three categories: relevant, possibly relevant, and not relevant to the question, with reviewer agreement measured using a weighted kappa statistic. The quality of items found to be ‘relevant’ and ‘possibly relevant’ was measured by impact factor ratings from Thomsen Reuters (ISI Web of Knowledge, when available, as well as information obtained by SCOPUS on the number of times items were cited.Main Results – Google Scholar results were judged to be more relevant and of higher quality than results obtained from PubMed. Google Scholar results are also older on average, while PubMed retrieved items from a larger number of unique journals.Conclusion – In agreement with earlier research, the authors recommended that searchers use both PubMed and Google Scholar to improve on the quality and relevance of results. Searches in the two resources identify unique items based upon the ranking algorithms involved.

  4. Use Google Scholar, Scopus and Web of Science for Comprehensive Citation Tracking. A review of: Bakkalbasi, Nisa, Kathleen Bauer, Janis Glover and Lei Wang. “Three Options for Citation Tracking: Google Scholar, Scopus and Web of Science.” Biomedical Digital Libraries 3.7 (2006.

    Directory of Open Access Journals (Sweden)

    Lorie A. Kloda

    2007-09-01

    Full Text Available Objective – To determine whether three competing citation tracking services result in differing citation counts for a known set of articles, and to assess the extent of any differences.Design – Citation analysis, observational study.Setting – Three citation tracking databases: Google Scholar, Scopus and Web of Science. Subjects – Citations from eleven journals each from the disciplines of oncology and condensed matter physics for the years 1993 and 2003.Methods – The researchers selected eleven journals each from the list of journals from Journal Citation Reports 2004 for the categories “Oncology” and “Condensed Matter Physics” using a systematic sampling technique to ensure journals with vary ingimpact factors were included. All references from these 22 journals were retrieved for the years 1993 and 2003 by searching three databases: Web of Science, INSPEC, and PubMed. Only research articles were included for the purpose of the study. From these, a stratified random sample was created to proportionally represent the content of each journal (oncology 1993: 234 references, 2003: 259 references; condensed matter physics 1993: 358 references, 2003: 364 references. In November of 2005, citations counts were obtained for all articles from Web of Science, Scopus and GoogleScholar. Due to the small sample size and skewed distribution of data, non‐parametric tests were conducted to determine whether significant differences existed between sets.Main Results – For 1993, mean citation counts were highest in Web of Science for both oncology (mean = 45.3, SD = 77.4 and condensed matter physics (mean = 22.5, SD= 32.5. For 2003, mean citation counts were higher in Scopus for oncology (mean = 8.9,SD = 12.0, and in Web of Science for condensed matter physics (mean = 3.0, SD =4.0. There was not enough data for the set of citations from Scopus for condensed matter physics for 1993 and it was therefore excluded from analysis. A Friedman test to measure for differences between all remaining groups suggested a significant difference existed, and so pairwise post‐hoc comparisons were performed. The Wilcoxon Signed Ranked tests demonstrated significant differences “in citation counts between all pairs (p Conclusion – The study does not confirm the authors’ hypothesis that differing scholarly coverage would result in different citation counts from the three databases. While there were significant differences in mean citation rates between all pairs of databases except for Google Scholar and Scopus in condensed matter physics for 2003, no one database performed better overall. Different databases performed better for different subjects, as well as for different years, especially Scopus, which only includes references starting in 1996. The results of this study suggest that the best citation database will depend on the years being searched as well as the subject area. For a complete picture of citation behaviour, the authors suggest all three be used.

  5. Chinese Marine Materia Medica. By Huashi Guan and Shuguang Wang. Shanghai Scientific and Technical Publishers, China Ocean Press, and Chemical Industry Press: Shanghai, Beijing, China, 2009; Hardback, 7064 pp; ¥ 2920; ISBN 978-7-5323-9958-1/R•2707; ISBN 978-7-5323-9973-4/R•2708; ISBN 978-7-1220-6012-9

    Directory of Open Access Journals (Sweden)

    Peter Proksch

    2014-01-01

    Full Text Available China is one of the first countries to use marine materia medica for treating diseases. Ancient books on Chinese herbology, such as Shennong Bencaojing (Shennong’s Classic of Materia Medica, Xinxiu Bencao (Newly Revised Materia Medica and Bencao Gangmu (Compendium of Materia Medica, have detailed more than 110 marine herbs and thousands of marine herbal formulas (including those for Chinese food therapy. A great deal of information on marine herbs and their applications in medicine, collected over thousands of years, has provided an important foundation for modern research in the area of marine drugs. Thanks to these records and references, the research and development of modern Chinese marine drugs continue to evolve and mature. Since the middle of the 20th century, special attention has been paid to traditional Chinese medicine, resulting in a significant increase in the number of newly discovered marine herbs. Comprehensive surveys in the past have also created a wealth of data on the pharmacology, chemistry, biology and ecology of marine medicinal bioresources. After thousands of years of research, historical references to traditional marine herbs are scattered throughout ancient books, local chronicles, medical books, or monographs on medicinal herbs. Unfortunately, there is no systematic way to collate or scientifically verify these references. Furthermore, during the last century, scientists around the world have accumulated large quantities of information on marine natural products, but these are also scattered throughout academic books and journals.

  6. Ocean acidification increases the accumulation of toxic phenolic compounds across trophic levels, supplement to: Jin, Peng; Wang, Tifeng; Liu, Nana; Dupont, Sam; Beardall, John; Boyd, Philip W; Riebesell, Ulf; Gao, Kunshan (2015): Ocean acidification increases the accumulation of toxic phenolic compounds across trophic levels. Nature Communications, 6, 8714

    KAUST Repository

    Jin, Peng

    2016-01-01

    Increasing atmospheric CO2 concentrations are causing ocean acidification (OA), altering carbonate chemistry with consequences for marine organisms. Here we show that OA increases by 46-212% the production of phenolic compounds in phytoplankton grown under the elevated CO2 concentrations projected for the end of this century, compared with the ambient CO2 level. At the same time, mitochondrial respiration rate is enhanced under elevated CO2 concentrations by 130-160% in a single species or mixed phytoplankton assemblage. When fed with phytoplankton cells grown under OA, zooplankton assemblages have significantly higher phenolic compound content, by about 28-48%. The functional consequences of the increased accumulation of toxic phenolic compounds in primary and secondary producers have the potential to have profound consequences for marine ecosystem and seafood quality, with the possibility that fishery industries could be influenced as a result of progressive ocean changes.

  7. 熊本城本丸御殿の障壁画-昭君の間,若松の間の復元にちなんで- The wall and sliding door paintings of the Honmaru Goten in Kumamoto Castle -The restoration of pictures in Wang Zhaojun chamber and Pine trees chamber -

    OpenAIRE

    脇坂, 淳

    2005-01-01

    熊本城の本丸御殿が平成19年を目差して復元建造中である。御殿大広間の障壁画も昭君の間と若松の間が復元されることになった。障壁画の復元は国の特別史跡地内にあってはじめてのケースになる。かつての障壁画は明治10年(1877)に建物とともに灰燼に帰した。その絵様は写真も遺されてなく,まったく知られていない。画題と筆者名だけを伝える18世紀後半の「御天守密書」,19世紀前半に杉谷行直によって縮写された昭君の間の天井画,これらのわずかな資料をもとに復元作業は進められている。古来,障壁画制作にはまず小下絵が作られた。それに倣い,往時の障壁画筆者狩野言信の吟味,王昭君が措かれた意味,時代様式などを踏まえ,小下絵の制作にかかる。小下絵に描かれた絵様に再三の検討を重ね,17世紀初頭に描かれた昭君の間と若松の間の絵様復元に至る研究である。 The Honmaru Goten in Kumamoto Castle will be completely restored to its original state in 2007. Consequently, the wall and sliding d...

  8. Comment on “High-temperature soft magnetic properties of antiperovskite nitrides ZnNFe{sub 3} and AlNFe{sub 3}” by Yankun Fu, Shuai Lin, and Bosen Wang, J. Magn. Magn. Mater. 378 (2015) 54–58

    Energy Technology Data Exchange (ETDEWEB)

    Scholz, T. [Chair of Solid-State and Quantum Chemistry, Institute of Inorganic Chemistry, Landoltweg 1, RWTH Aachen University, D-52056 Aachen (Germany); Leineweber, A. [Institute of Materials Science, TU Bergakademie Freiberg, Gustav-Zeuner-Str. 5, D-09599 Freiberg (Germany); Dronskowski, R., E-mail: drons@HAL9000.ac.rwth-aachen.de [Chair of Solid-State and Quantum Chemistry, Institute of Inorganic Chemistry, Landoltweg 1, RWTH Aachen University, D-52056 Aachen (Germany)

    2016-10-15

    The authors of the aforementioned manuscript have recently claimed the synthesis of the ternary nitrides ZnNFe{sub 3} (=ZnFe{sub 3}N) and AlNFe{sub 3} (=AlFe{sub 3}N), ordered substituted variants of the binary phase γ‘-Fe{sub 4}N [1]. While soft ferromagnets of such kind are presently attracting lots of attention, their history dates back for more than half a century. In particular, Al-substituted γ‘-Fe{sub 4}N has already been mentioned in 1961 [2], and the existence of AlFe{sub 3}N has also been claimed in 2009 [3] from a two-step ammonolysis reaction combining a high-temperature sintering step and a low-temperature nitriding reaction [4]. Nonetheless, one of us had to withdraw the latter claim after finding out, by means of scanning-electron microscopy and elemental mapping, that all samples of “AlFe{sub 3}N” consisted of an intimate solid mixture of γ‘-Fe{sub 4}N and amorphous Al{sub 2}O{sub 3}[5]. From what follows, we have strong reasons to believe that the authors of Ref. [1] overlooked our findings [5] and also did not synthesize ZnFe{sub 3}N and AlFe{sub 3}N. - Highlights: • The synthesis of ZnFe{sub 3}N and AlFe{sub 3}N is questioned. • The diffraction data of ZnFe{sub 3}N and AlFe{sub 3}N resemble those of Fe{sub 4}N. • The magnetic data of ZnFe{sub 3}N and AlFe{sub 3}N are compatible with those of Fe{sub 4}N. • There is no physical evidence for the existence of ZnFe{sub 3}N and AlFe{sub 3}N.

  9. Effects of ice storm on forest ecosystem of southern China in 2008 Shaoqiang Wang1, Lei Zhou1, Weimin Ju2, Kun Huang1 1Key Lab of Ecosystem Network Observation and Modeling, Institute of Geographical Sciences and Natural Resources Research, Beijing, 10010

    Science.gov (United States)

    Wang, Shaoqiang

    2014-05-01

    Evidence is mounting that an increase in extreme climate events has begun to occur worldwide during the recent decades, which affect biosphere function and biodiversity. Ecosystems returned to its original structures and functions to maintain its sustainability, which was closely dependent on ecosystem resilience. Understanding the resilience and recovery capacity of ecosystem to extreme climate events is essential to predicting future ecosystem responses to climate change. Given the overwhelming importance of this region in the overall carbon cycle of forest ecosystems in China, south China suffered a destructive ice storm in 2008. In this study, we used the number of freezing day and a process-based model (Boreal Ecosystem Productivity Simulator, BEPS) to characterize the spatial distribution of ice storm region in southeastern China and explore the impacts on carbon cycle of forest ecosystem over the past decade. The ecosystem variables, i.e. Net primary productivity (NPP), Evapotranspiration (ET), and Water use efficiency (WUE, the ratio of NPP to ET) from the outputs of BEPS models were used to detect the resistance and resilience of forest ecosystem in southern China. The pattern of ice storm-induced forest productivity widespread decline was closely related to the number of freezing day during the ice storm period. The NPP of forest area suffered heavy ice storm returned to normal status after five months with high temperature and ample moisture, indicated a high resilience of subtropical forest in China. The long-term changes of forest WUE remain stable, behaving an inherent sensitivity of ecosystem to extreme climate events. In addition, ground visits suggested that the recovery of forest productivity was attributed to rapid growth of understory. Understanding the variability and recovery threshold of ecosystem following extreme climate events help us to better simulate and predict the variability of ecosystem structure and function under current and future climate change.

  10. 專論/品質保證應用在圖書資訊學數位課程發展之行動研究/王梅玲、陳巧倫(Mei-Ling Wang; Ciao-Lun Chen

    Directory of Open Access Journals (Sweden)

    王梅玲、陳巧倫 Mei-Ling Wang; Ciao-Lun Chen

    2009-10-01

    Full Text Available 網際網路促成數位學習發展,如今成為高等教育潮流,美國10 餘所圖書資訊學研究所提供數位碩士學程已培養許多圖書館專業人才。我國公共圖書館與學校圖書館普遍存在許多工作人員未受過專業教育的問題,因此圖書資訊學數位課程與學程長久以來受到期待。本論文基於數位學習品質保證原理,以行動研究方法,探討圖書資訊學數位課程的設計與發展。研究目的包括:(1)探討數位學習品質保證原理與機制;(2)運用品質保證規範以設計數位課程;(3)以行動研究發展圖書資訊學數位學習專班與數位課程;(4)檢討品質保證對數位課程發展之成效。本研究於2007年至2008 年間研發六門數位課程,包括知識組織與資訊取用、研究方法、學校圖書館管理、檔案學研究、圖書資訊學研討與數位圖書館等課程,利用行動研究,規劃與發展課程,並藉課程評鑑回饋修正,最後總結並提出建議。 E-learning is flourishing in higher education due to its ability to lift time and place restrictions from teaching and learning. Because many library staff has not received professional education, more E-learning curricula and programs by Library and Information Science schools is something that many libraries in Taiwan look forward to. Facing demand for E-learning from library staff, the Graduate Institute of Library, Information and Archival Studies (LIAS at National Cheng-Chi University undertook an experimental curriculum project. The purpose of this study was to develop an E-learning master’s program with six E-learning curricula for library staff and instructors in senior high schools in accordance with quality assurance mechanism .The study was conducted as action research with five stages as follows: (a describing the problem and its focus; (b exploring some action options for the problem; (cseeking collaborative partners and discussing; (dundertaking action options: the five lecturers of the LIAS planned and developed six E-learning courses with web-based learning systems; (f evaluation and feedback: six courses were modified according to student learning outcome assessments and course reviews. In 2008, six E-learning courses were developed and program and curricular accreditation was applied for from the Ministry of Education. Six e-learning courses were Information, Organization and Access; Research Methodology; School Library Management; Seminar on Archival Studies; Seminar on Library and Information Science; and Digital Libraries. In addition to describing the planning and implementation of the curriculum, the article also reviews the effectiveness of E-learning teaching and learning, as well as offering final conclusions and recommendations. 頁次:54-65

  11. Reply to the comment by Q.Q. Qiao et al. on ;Cenozoic tectonic deformation and uplift of the South Tian Shan: Implications from magnetostratigraphy and balanced cross-section restoration of the Kuqa depression; by Tao Zhang, Xiaomin Fang, Chunhui Song, Erwin Appel, and Yadong Wang [Tectonophysics, 2014, doi:10.1016/j.tecto.2014.04.044

    Science.gov (United States)

    Zhang, Tao; Fang, Xiaomin; Song, Chunhui; Appel, Erwin; Wang, Yadong

    2017-07-01

    Qiao et al. (2016) commented on our work (Zhang et al., 2014) and rejected our reinterpretation of the magnetostratigraphic results of Huang et al. (2006) and Li et al. (2006), with the results gained using the Dynamic Time Warping Algorithm technique (DTWAT) as their main basis. However, Qiao et al. (2016) did not provide details of their modeling inputs, and, in particular, the parameters they chose for their calculations, where such parameters can have a serious impact upon any results. We therefore performed calculations using the same software (i.e., Qupydon) as Qiao et al. (2016), using reliable parameter settings. The results showed that the ;interesting correlation; of a 6000 minimum cost output completely correlate with the magnetostratigraphic Chrons C18r to C3An.1n ( 40-6 Ma), which is consistent with our reinterpreted magnetostratigraphic results. Furthermore, we summarized previous biostratigraphic studies of nearby areas; the data resulting from this process also supported our reinterpreted magnetostratigraphic correlation. We were therefore able to confirm the revised magnetostratigraphic correlation of Zhang et al. (2014).

  12. Comment on "Cenozoic tectonic deformation and uplift of the South Tian Shan: Implications from magnetostratigraphy and balanced cross-section restoration of the Kuqa depression" by Tao Zhang, Xiaomin Fang, Chunhui Song, Erwin Appel, and Yadong Wang [Tectonophysics, 2014, doi:10.1016/j.tecto.2014.04.044

    Science.gov (United States)

    Qiao, Qingqing; Huang, Baochun; Piper, John D. A.

    2016-10-01

    The recent paper entitled: "Cenozoic tectonic deformation and uplift of the South Tian Shan: Implications from magnetostratigraphy and balanced cross-section restoration of the Kuqa depression" by Zhang et al. [Tectonophysics, 2014, doi:10.1016/j.tecto.2014.04.044] discusses the Cenozoic tectonic deformation and uplift of the South Tianshan Mountains by integrating tectonic investigations, seismostratigraphic analysis and paleomagnetic dating of the thrust-fold belt in the Kuqa Depression at the southern border of the Tianshan. To support their conclusions the authors have reinterpreted a high resolution magnetostratigraphic study of the Kezilenuer Section in a paper entitled "Magnetostratigraphic study of the Kuche Depression, Tarim Basin, and Cenozoic uplift of the Tian Shan Range, Western China" by Huang et al. [Earth and Planetary Science Letters Volume 251, pages 346-364 (2006)]. We note here (i) that apparent conflicts in definition of the Xiyu Formation in the Kuche Depression as proposed by Zhang et al. (2014) require amplification and (ii) argue that their age assignment for the Kezilenuer Section is incorrect and yields an anomalously low sedimentation rate for the infilling of this foreland basin.

  13. Clinical efficacy of percutaneous vertebroplasty combined with intensity-modulated radiotherapy for spinal metastases in patients with NSCLC

    Directory of Open Access Journals (Sweden)

    Li Y

    2015-08-01

    Full Text Available Yi Li,1,2 Yi Qing,1 Zhimin Zhang,3 Mengxia Li,1 Jiaying Xie,1 Ge Wang,1 Dong Wang1 1Department of Cancer Center, Research Institute of Surgery, Daping Hospital, Third Military Medical University, 2Department of Oncology, Beibei Traditional Chinese Medical Hospital, Chongqing, 3Department of Oncology, Wuhan General Hospital of Guangzhou Command, People’s Liberation Army, Wuhan, Hubei, People’s Republic of China Objective: This study aimed to evaluate the safety and efficacy of percutaneous vertebroplasty (PVP combined with intensity-modulated radiotherapy (IMRT for metastatic lesions of patients with non-small-cell lung cancer (NSCLC at centrum vertebrae.Methods: A total of 39 patients with spinal metastatic NSCLC (stage IV were treated with PVP followed by IMRT (30 Gy/10F/2 W for metastatic lesion at centrum vertebrae under local anesthesia. Retrospective analysis was done with medical records and radiological data. The change of visual analog scale (VAS, activities of daily living, and kyphotic angle was measured preoperatively. The presence of complications was assessed preoperatively (baseline at 24 hours, 1 week, and 1, 3, 6, 12, and 24 months postoperatively, or until the patient died or was lost to follow-up. Survival was assessed in the group.Results: A total of 39 consecutive patients were successfully treated with PVP via a translateral approach and IMRT. Their mean VAS score decreased from 7.93±1.09 preoperatively to 4.14±1.15 by the 24-hour postoperative time point and was 3.92±1.23 at 1 week, 4.27±1.93 at 1 month, 3.24±1.35 at 3 months, 2.27±0.96 at 6 months, and 2.59±1.55 at 12 months after the procedure. The mean VAS score at all of the postoperative time points was decreased significantly from the preoperative baseline score (P<0.05. Activities of daily living evaluation showed that the patients had a significantly high life quality after the combined approach (50.9±11.7 vs 82.3±9.9, P<0.05. No severe complications

  14. A taxonomic study on the genus Tectodamaeus Aoki (Acari, Oribatida, Damaeidae, with description of two new species from China

    Directory of Open Access Journals (Sweden)

    Lixia Xie

    2009-09-01

    Full Text Available Two new species of the genus Tectodamaeus from Yunnan and Anhui Province respectively, China are described, Tectodamaeus daliensis sp. n., Tectodamaeus longus sp. n. Nine new combinations, Tectodamaeus costanotus (Wang & Norton comb. n., Tectodamaeus exspinosus (Wang & Norton comb. n., Tectodamaeus wulongensis (Wang & Cui comb. n., Tectodamaeus brevisetus (Wang comb. n., Tectodamaeus spiniger (Wang comb. n., Tectodamaeus exsertus (Wang comb. n., Tectodamaeus yaoi (Wang comb. n., Tectodamaeus furcatus (Wang & Lu comb. n., Tectodamaeus cuii (Wang & Lu comb. n. are presented. The subgenus Damaeus (Tectodamaeus as a genus in the oribatid mite family Damaeidae was reestablished. A key is given to distinguish all the species of the genus. Th e type specimens of the new species are deposited in the Institute of Entomology, Guizhou University (IEGU.

  15. Dirac equation with spin symmetry for the modified Pöschl–Teller ...

    Indian Academy of Sciences (India)

    equipment for the analysis of cultural heritage. 313. Chakraborty A see Sudarshan M. 241. Chandra Hem see Upadhyay Sanjay. 183. Chatterjee J M see Gupta D. 345. Chen Jiao-Kai. Separation of different wave components in the Bethe–Salpeter wave function. 397. Chettle D R. In vivo applications of X-ray fluorescence.

  16. Inhibitory effect of puerarin on proliferation of retinoblastoma cells ...

    African Journals Online (AJOL)

    Wei-Jiao Zhan, Jian-Feng Zhu, Ying Zhang*. Department of Ophthalmology, Linyi People`s Hospital, Linyi, Shandong, 276000, China ... remains a leading cause of death worldwide. [1,2]. Retinoblastoma is a malignant intraocular tumor that affects infants and children [3]. If undiagnosed or untreated, patients with.

  17. Little Fish in a Big Pond: Towards Research Performance Metrics for Smaller Institutions

    Science.gov (United States)

    Kitt, Sharon; Wearne, Jonathan

    2013-01-01

    Each year, institutions eagerly await reports from "Shanghai Jiao Tong University," "Times Higher," "QS," and other organisations that create and publish international rankings of university performance. The metrics included in league tables and rankings--research income, research staff, number of doctoral candidates,…

  18. Identification of a taxol-producing endophytic fungus EFY-36

    African Journals Online (AJOL)

    STORAGESEVER

    2009-06-03

    Jun 3, 2009 ... 1Plant Biotechnology Research Center, Shanghai Key Laboratory of Agrobiotechnology, School of Agriculture and. Biology, Fudan-SJTU-Nottingham Plant Biotechnology R and D Center, Shanghai Jiao Tong University, Shanghai. 200240 .... producing endophytic fungi by restriction enzyme-mediated.

  19. The 2012 Ming K Jeang award for excellence in cell & bioscience.

    Science.gov (United States)

    Shi, Yun-Bo

    2013-05-23

    Three research groups led by Dr. Lixin Feng of Shanghai JiaoTong University School of Medicine, Shanghai, China, Dr. Walter Wahli of University of Lausanne, Lausanne, Switzerland, and Dr. Gutian Xiao of University of Pittsburgh Cancer Institute, Pittsburgh, USA, won the 2012 Ming K Jeang Award for Excellence in Cell & Bioscience.

  20. Keeping Tradition

    NARCIS (Netherlands)

    Zenhong, C.; Buwalda, P.L.

    2011-01-01

    Chinese dumplings such as Jiao Zi and Bao Zi are two of the popular traditional foods in Asia. They are usually made from wheat flour dough (rice flour or starch is sometimes used) that contains fillings. They can be steamed, boiled and fried and are consumed either as a main meal or dessert. As

  1. Methodology, Meaning and Usefulness of Rankings

    Science.gov (United States)

    Williams, Ross

    2008-01-01

    University rankings are having a profound effect on both higher education systems and individual universities. In this paper we outline these effects, discuss the desirable characteristics of a good ranking methodology and document existing practice, with an emphasis on the two main international rankings (Shanghai Jiao Tong and THES-QS). We take…

  2. We'll Support You Ever More!

    Science.gov (United States)

    Gora, Joseph

    2011-01-01

    In this article the author discusses public reaction generated by the Times Higher Education (THE) World University Rankings. He argues that it is not simply that the methodologies adopted by the main rankers -- Times Higher Education (THE), QS and the Shanghai Jiao Tong University -- are diverse and open to the usual interpretation, but there…

  3. Global Status, Intra-Institutional Stratification and Organizational Segmentation: A Time-Dynamic Tobit Analysis of ARWU Position among U.S. Universities

    Science.gov (United States)

    Cantwell, Brendan; Taylor, Barrett J.

    2013-01-01

    Ranking systems such as "The Times Higher Education's World University Rankings" and Shanghai Jiao Tong University's "Academic Rankings of World Universities" simultaneously mark global status and stimulate global academic competition. As international ranking systems have become more prominent, researchers have begun to examine whether global…

  4. Controlling of morphology of Ni/Al-LDHs using microemulsion ...

    Indian Academy of Sciences (India)

    Wintec

    Controlling of morphology of Ni/Al-LDHs using microemulsion- mediated hydrothermal synthesis. YUN ZHAO.. *, FENFEI XIAO and QINGZE JIAO. School of Chemical Engineering and Environment, Beijing Institute of Technology, Beijing 100081, P.R. China. MS received 25 February 2008; revised 18 April 2008. Abstract.

  5. to view fulltext PDF

    Indian Academy of Sciences (India)

    ... wave function: Fermion–scalar case and scalar–scalar case . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Chong Chen and Jiao-Kai Chen. 809. Cluster decay of 112−122Ba isotopes from ground state and as an excited compound system. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .K P Santhosh, P V Subha and B Priyanka.

  6. Entanglement Rate for Gaussian Continuous Variable Beams

    Science.gov (United States)

    2016-08-24

    for Gaussian continuous variable beams Zhi JiaoDeng1,2, Steven JMHabraken1 and FlorianMarquardt1,3 1 Institut für Theoretische Physik II, Friedrich...91058 Erlangen, Germany E-mail: Florian.Marquardt@physik.uni-erlangen.de Keywords: entanglement rate, entangledGaussian beams , optomechanics Abstract

  7. Erratum to: Boson bound states in the β-Fermi–Pasta–Ulam model

    Indian Academy of Sciences (India)

    XIN-GUANG HU1, JU XIANG2,∗. , ZHENG JIAO1, YANG LIU3,. GUO-QIU XIE1 and KE HU4. 1Department of Physics, Huangshan University, Huangshan 245041, Anhui, China. 2Department of Basic Sciences, The First Aeronautical Institute of the Air Force, Xinyang 464000,. Henan, China. 3Department of Basis, Air Force ...

  8. Voltammetric determination of heparin based on its interaction with

    African Journals Online (AJOL)

    a

    For example, Jiao et al. investigated the interaction between some cationic dyes such as azure A, methylene blue and azure B with heparin by absorption spectrophotometry [13]. Sun et al. applied brilliant cresyl blue and neutral red for spectrophotometric determination of heparin [14,. 15]. Liu et al. established a resonance ...

  9. APPLICATION OF o-TOLIDINE AS SUBSTRATE FOR THE ...

    African Journals Online (AJOL)

    *Corresponding author. E-mail: sunwei_1975@public.qd.sd.cn. APPLICATION OF o-TOLIDINE AS SUBSTRATE FOR THE ELECTROCHEMICAL. DETERMINATION OF HEMOGLOBIN OR HYDROGEN PEROXIDE. Wei Sun*, Hong Jiang, Jianghua Zhong and Kui Jiao. College of Chemistry and Molecular Engineering, ...

  10. Response to Comment on "Dilution limits dissolved organic carbon utilization in the deep ocean"

    KAUST Repository

    Arrieta, Jesus

    2015-12-18

    Our recent finding that dilution limits dissolved organic carbon (DOC) utilization in the deep ocean has been criticized based on the common misconception that lability equates to rapid and complete utilization. Even when considering the redefinition of recalcitrant DOC recently proposed by Jiao et al., the dilution hypothesis best explains our experimental observations.

  11. A case report on ATP6V0A4 gene mutation: Forecast of familial ...

    African Journals Online (AJOL)

    A case report on ATP6V0A4 gene mutation: Forecast of familial deafness by genetic investigation in a patient with autosomal recessive distal renal tubular acidosis. Weihua Zheng, Ying Wu* and Wenyan Huang. Shanghai Children's Hospital, Shanghai Jiao Tong University, Shanghai 200062, China. *For correspondence: ...

  12. Tropical Journal of Pharmaceutical Research - Vol 16, No 3 (2017)

    African Journals Online (AJOL)

    Therapeutic effects of Saikosapoin D on bleomycininduced pulmonary fibrosis in mice via regulation of IL- 33/ST2 pathway · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. Jiao Xu, Xiao-hui Miao, Jin-xu Zheng, Ming Ding, Zhi-fang Zhuang, 581-588.

  13. Phase-Resolved Spectra of PSR B0525+21 and PSR B2020+28 JL ...

    Indian Academy of Sciences (India)

    Jiao-Ke (2009)), GDUPS (2009) and NFSC project 10673021. References. Chen, J. L. et al. 2007, Chinese J. Astron. Astrophys., 7, 789. Cordes, J. M. 1978, Astrophys. J., 222, 1006. Kuzmin, A. D., Izvekova, V. A., et al. 1998, Astron. Astropys.

  14. Effective Spectral Indices of Core and Extended Emissions for Radio ...

    Indian Academy of Sciences (India)

    Municipality (No. 11 Sui-Jiao-Ke [2009]), the Guangdong Province Universities and Colleges Pearl River Scholar Funded Scheme (GDUPS) (2009), the Yangcheng. Scholar Funded Scheme (10A027S), the support for Astrophysics Key Subject of. Guangzhou City, and the research fund of Hunan University of Arts and ...

  15. Correlation between the Flux Density and Polarization for Flat ...

    Indian Academy of Sciences (India)

    Education of Guangzhou Municipality (No. 11 Sui-Jiao-Ke 2009), and Guangdong. Province Universities and Colleges Pearl River Scholar Funded Scheme (GDUPS). (2009). This research has made use of data from the University of Michigan Radio. Astronomy Observatory which has been supported by the University of ...

  16. African Journal of Traditional, Complementary and Alternative ...

    African Journals Online (AJOL)

    Effects of Chinese materia medica-fuboa danggui jiao on experimental endometriosis · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. S Xing, C Lijue, Z Fanbo. http://dx.doi.org/10.4314/ajtcam.v8i3.65283 ...

  17. Effects of photoperiod on energy metabolism and thermogenesis in ...

    African Journals Online (AJOL)

    Administrator

    2010-12-27

    1999). Effects of temperature and photoperiod on thermogenesis in plateau pikas (Ochotona curzoniae) and root voles (Microtus oeconomus). J. Comp. Physiol. 169: 77-83. Wang DH, Sun RY, Wang ZW, Liu JS, Chen Z (1996).

  18. China and the New International Order

    DEFF Research Database (Denmark)

    Jiang, Yang

    2009-01-01

    This article reviews the book "China and the New International Order," edited by Wang Gungwu and Zheng Yongnian.......This article reviews the book "China and the New International Order," edited by Wang Gungwu and Zheng Yongnian....

  19. African Journal of Biotechnology - Vol 8, No 8 (2009)

    African Journals Online (AJOL)

    Cloning and analysis of the HMG domains of ten Sox genes from Bombina maxima (Amphibia: Anura) · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. J Wang, N Wang, L Nie ...

  20. Observations of Binary and Millisecond Pulsars at Xinjiang ...

    Indian Academy of Sciences (India)

    2016-01-27

    Jan 27, 2016 ... Author Affiliations. Jingbo Wang1 2 Na Wang1 Jianping Yuan1 Zhiyong Liu1. Xinjiang Astronomical Observatory, CAS, 150, Science 1-Street, Urumqi 830011, China. University of Chinese Academy of Sciences, Beijing 100049, China.

  1. Quantum capacitance of the armchair-edge graphene nanoribbon

    Indian Academy of Sciences (India)

    101, 026803 (2008). [22] P Avouris, Z Chen and V Perebeinos, Nat. Nanotechnol. 2, 60 (2007). [23] L F Mao, X J Li, Z O Wang and J Y Wang, IEEE Electron Device Lett. 29, 1047 (2008). [24] L F Mao, Nanotechnol. 20, 275203 (2009). [25] L F Mao, X J Li, C Y Zhu, Z O Wang, Z H Lu, J F Yang, H W Zhu, Y S Liu and J Y Wang,.

  2. Frontiers in biochip technology

    National Research Council Canada - National Science Library

    Xing, Wan-Li; Cheng, Jing

    2006-01-01

    ... . . . . . . . . . . . . . . . . . . . . . . . . . . . . Haiching Ma, Yuan Wang, Amy S. Pomaybo, and Connie Tsai 2. Improvement of Microarray Technologies for Detecting Single Nucleotide Mismatch...

  3. Choline-based biodegradable ionic liquid catalyst for Mannich-type ...

    Indian Academy of Sciences (India)

    Chem. Sus. Chem. 5 1223; (b) Chen X, Souvanhthong. B, Wang H, Zheng H, Wang X and Huo M 2013 Appl. Catal. B 138–139 161. 12. (a) Zhu A L, Liu R X, Li L J, Li L Y, Wang L and. Wang J J 2009 Catal. Today 200 17; (b) Ilgen F, Ott D,. Kralisch D, Reil C, Palmberger A and Konig B 2009. Green. Chem. 11 1948. 13.

  4. Artificial Oxide Heterostructures with Tunable Band Gap

    Science.gov (United States)

    2016-12-20

    epitaxially grown CaMnO3, Applied Physics Letters , 108, 082902 (2016). 2. Hongwei Wang, Igor V. Solovyev, Wenbin Wang, Xiao Wang, Philip J. Ryan...Based on the above joint experimental and theoretical analysis, in a recently published paper on Applied Physics Letters1 in 2015, we...the improper multiferroicity in h-LuFeO3 films, submitted ro Physics Review Letters , arXiv:1610.00073 [cond-mat.mtrl-sci] 4. Hongwei Wang, Lixin He

  5. Neuroprotective effect of β-asarone against Alzheimer’s disease: regulation of synaptic plasticity by increased expression of SYP and GluR1

    Directory of Open Access Journals (Sweden)

    Liu SJ

    2016-04-01

    Full Text Available Si-jun Liu,1,* Cong Yang,2,* Yue Zhang,2,* Ru-yu Su,2 Jun-li Chen,2 Meng-meng Jiao,2 Hui-fang Chen,2 Na Zheng,2 Si Luo,2 Yun-bo Chen,2 Shi-jian Quan,1 Qi Wang21School of Chinese Materia Medica, 2Institute of Clinical Pharmacology, Guangzhou University of Chinese Medicine, Guangzhou, People’s Republic of China*These authors contributed equally to this workAim: β-asarone, an active component of Acori graminei rhizome, has been reported to have neuroprotective effects in Alzheimer’s disease. As the underlying mechanism is not known, we investigated the neuroprotective effects of β-asarone in an APP/PS1 double transgenic mouse model and in NG108 cells.Materials and methods: APPswe/PS1dE9 double transgenic male mice were randomly assigned to a model group, β-asarone treatment groups (21.2, 42.4, or 84.8 mg/kg/d, or donepezil treatment group (2 mg/kg/d. Donepezil treatment was a positive control, and background- and age-matched wild-type B6 mice were an external control group. β-asarone (95.6% purity was dissolved in 0.8% Tween 80 and administered by gavage once daily for 2.5 months. Control and model animals received an equal volume of vehicle. After 2.5 months of treatment, behavior of all animals was evaluated in a Morris water maze. Expression of synaptophysin (SYP and glutamatergic receptor 1 (G1uR1 in the hippocampus and cortex of the double transgenic mice was assayed by Western blotting. The antagonistic effects of β-asarone against amyloid-β peptide (Aβ were investigated in vitro in the NG108-15 cell line. After 24 hours of incubation, cells were treated with 10 µm Aβ with or without β-asarone at different concentrations (6.25, 12.5, or 25 µM for an additional 36 hours. The cytotoxicity of β-asarone was evaluated by 3-(4,5-dimethylthiazol-2-yl-2,5-diphenyltetrazolium bromide assay of cell viability, and cell morphology was evaluated by bright-field microscopy after 24 hours of treatment. The expression of SYP and GluR1 in

  6. Journal of Genetics | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Genetics. YANG LUO. Articles written in Journal of Genetics. Volume 90 Issue 2 August 2011 pp 339-342 Research Note. Novel vitamin D 1-hydroxylase gene mutations in a Chinese vitamin-D-dependent rickets type I patient · Lihua Cao Fang Liu Yu Wang Jian Ma Shusen Wang Libo Wang ...

  7. Quantitative trait loci mapping and genetic dissection for lint ...

    Indian Academy of Sciences (India)

    2014-08-01

    Aug 1, 2014 ... [Wang M., Li C. and Wang Q. 2014 Quantitative trait loci mapping and genetic dissection for lint percentage in upland cotton (Gossypium hirsutum). J. Genet. ... nents and has high heritability in upland cotton (G. hirsu- tum). Lint percentage ... quality, and disease and insect resistance (Wang 2004). TM-.

  8. AUTHOR INDEX

    Indian Academy of Sciences (India)

    Bhatt H C. Disks around young stellar objects. 19. Bhattacharya Dipankar. Beyond the Chandrasekhar limit: Structure and formation of compact stars. 29 ..... The legacy of S Chandrasekhar (1910–1995). 213. Wang Bao-Yan see Wang Chun-Yan. 759. Wang Chun-Yan. The classification of single travelling wave solutions to ...

  9. Novel vitamin D 1α-hydroxylase gene mutations in a Chinese ...

    Indian Academy of Sciences (India)

    hydroxylase gene mutations in a Chinese vitamin-D-dependent rickets type I patient. Lihua Cao Fang Liu Yu Wang Jian Ma Shusen Wang Libo Wang Yang Zhang Chen Chen Yang Luo Hongwei Ma. Research Note Volume 90 Issue 2 August ...

  10. Microsatellite markers associated with body and carcass weights in ...

    African Journals Online (AJOL)

    enoh

    2012-02-21

    Feb 21, 2012 ... Body weight and carcass traits were under intensive selection for more .... All previous muscles and organs were also calculated as ..... Sel. Evol. J. 38: 85-97. Liu X, Li H, Wang S, Hu X, Gao Y, Wang Q, Li N, Wang Y, Zhang H.

  11. Novel vitamin D 1α-hydroxylase gene mutations in a Chinese ...

    Indian Academy of Sciences (India)

    2011-08-19

    hydroxylase gene mutations in a Chinese vitamin-D-dependent rickets type I patient. LIHUA CAO1, FANG LIU2, YU WANG1, JIAN MA2, SHUSEN WANG1, LIBO WANG2, YANG ZHANG1,. CHEN CHEN1, YANG LUO1∗ and HONGWEI ...

  12. Tropical Journal of Pharmaceutical Research - Vol 15, No 2 (2016)

    African Journals Online (AJOL)

    ... Ligustrazene Derivative by Irritation of Vascular Endothelial Growth Factor Expression in Middle Cerebral Artery Occlusion Rats · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. Zhang Huazheng, Wang Penglong, Ren Liwei, Wang Xiaobo, Li Guoliang, Wang Mina, ...

  13. Proliferative Activity and Neuroprotective Effect of Ligustrazene ...

    African Journals Online (AJOL)

    Proliferative Activity and Neuroprotective Effect of. Ligustrazene Derivative by Irritation of Vascular. Endothelial Growth Factor Expression in Middle Cerebral. Artery Occlusion Rats. Zhang Huazheng1, Wang Penglong2, Ren Liwei1, Wang Xiaobo2, Li Guoliang2,. Wang Mina1, Chu Fuhao2, Gong Yan2, Xu Bing2, Bi Siling1, ...

  14. Cloning and analysis of the HMG domains of ten Sox genes from ...

    African Journals Online (AJOL)

    STORAGESEVER

    2009-04-20

    Apr 20, 2009 ... Full Length Research Paper. Cloning and analysis of the HMG domains of ten Sox genes from Bombina maxima (Amphibia: Anura). Jingjing Wang, Ning Wang and Liu-wang Nie*. The Provincial Key Lab. of the Conservation and Exploitation Research of Biological Resources in Anhui, College of Life.

  15. Evaluation of NF-B Signaling in T Cells

    Science.gov (United States)

    2009-01-01

    Matsumoto, R., D. Wang, M. Blonska, H. Li, M. Kobayashi, B. Pappu , Y. Chen, D. Wang, and X. Lin. 2005. Phosphorylation of CARMA1 plays a critical...2006. Antigen-receptor signaling to nu- clear factor B. Immunity 25: 701–715. 4. Matsumoto, R., D. Wang, M. Blonska, H. Li, M. Kobayashi, B. Pappu

  16. Evaluation of NF-kappaB Signaling in T Cells

    Science.gov (United States)

    2009-01-01

    M. Blonska, H. Li, M. Kobayashi, B. Pappu , Y. Chen, D. Wang, and X. Lin. 2005. Phosphorylation of CARMA1 plays a critical role in T Cell receptor...receptor signaling to nu- clear factor B. Immunity 25: 701–715. 4. Matsumoto, R., D. Wang, M. Blonska, H. Li, M. Kobayashi, B. Pappu , Y. Chen, D. Wang, and

  17. Journal of Genetics | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Genetics. JIAN MA. Articles written in Journal of Genetics. Volume 90 Issue 2 August 2011 pp 339-342 Research Note. Novel vitamin D 1-hydroxylase gene mutations in a Chinese vitamin-D-dependent rickets type I patient · Lihua Cao Fang Liu Yu Wang Jian Ma Shusen Wang Libo Wang Yang ...

  18. Journal of Genetics | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Genetics. SHUSEN WANG. Articles written in Journal of Genetics. Volume 90 Issue 2 August 2011 pp 339-342 Research Note. Novel vitamin D 1-hydroxylase gene mutations in a Chinese vitamin-D-dependent rickets type I patient · Lihua Cao Fang Liu Yu Wang Jian Ma Shusen Wang Libo ...

  19. Comparative study of intestine length, weight and digestibility on ...

    African Journals Online (AJOL)

    Comparative study of intestine length, weight and digestibility on different body weight chickens. HM Yang, W Wang, ZY Wang, J Wang, YJ Cao, YH Chen. Abstract. This experiment was conducted to compare the difference of digestibility on different body weight chickens. Twenty-seven (27) 58-week-old New Yangzhou ...

  20. African Journal of Biotechnology - Vol 12, No 32 (2013)

    African Journals Online (AJOL)

    Comparative study of intestine length, weight and digestibility on different body weight chickens · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. HM Yang, W Wang, ZY Wang, J Wang, YJ Cao, YH Chen ...

  1. Dyamical Systems Theory and Lagrangian Data Assimilation in 4D Geophysical Fluid Dynamics

    Science.gov (United States)

    2017-06-30

    240(2), 166-179. Wang, P. and T. M. Ozgokmen, 2016. Spiral inertial waves radiated from geophysical vortices. Ocean Modelling, 99, 22-42. Wang, P...Environmental Buoyancy-Driven Flows, doi: 10.1007/s l 0652-016-9491-y. Wang, P. and T. M. Ozgokmen, 2015. How do hydrodynamic instabilities affect 3D

  2. A New Discussion of Sino-Korean Relations during the Chosŏn Period

    Directory of Open Access Journals (Sweden)

    Adam Bohnet

    2014-09-01

    Full Text Available Pae Usŏng 배우성, Chosŏn kwa Chunghwa: Chosŏn i kkumkkugo sangsanghan segye wa munmyŏng 조선과 중화: 조선이 꿈꾸고 상상한 세계와 문명 [Chosŏn and Chunghwa: The world and civilization that Chosŏn dreamt and imagined]. Kyŏnggi-do P'aju-si: Tolbegae, 2014. ISBN: 978-89-7199-597-6. In this book, Pae Usŏng, a historian at the University of Seoul, takes a fresh look at the relationship of Chosŏn Korea (1392–1910 with China and that of Chosŏn’s yangban (scholar-officials with Sinitic civilization as a whole. None of Chosŏn’s relationships were more important, or more complicated, than that with China. On the one hand, Chosŏn was in nearly all respects independent from both Ming (1368–1644 and Qing (1644–1912 China. On the other hand, under both the Ming and the Qing, the Chosŏn court sent envoys regularly to Beijing, thereby acknowledging its subservience to China. After the Manchu Qing supplanted the Ming in the mid-eighteenth century, most Chosŏn officials, privately at least, rejected the Qing as an empire controlled by barbarians. Following the Qing conquest, most Chosŏn scholar-officials also asserted that China’s cultural and political traditions had been irreparably lost within China proper, and that Chosŏn was the only remaining heir of the Sinitic tradition. Even so, no Chosŏn person of significance before the late nineteenth century actually called for the removal of Chosŏn from the Sinitic world, no matter how much the legitimacy of the Qing was doubted...

  3. 清代中期社会における奢侈・流行・消費:江南地方を中心として

    OpenAIRE

    則松彰文

    1998-01-01

    Since the mld-18th century (mid-Qing era), as a result of massive consumption the problem of luxurious lifestyle had been highlighted. Particularly in the Jiangnan (江南) area, the tendency of luxurious lifestyle was an accepted idea shared among many intellectuals.In 1781, against the request of the enforcement of sumptuary laws, the emperor (乾隆帝) regarded the trend at the time as a social rage that was virtually impossible to ban by human power.This trend during the mid-Qing era had great inf...

  4. Thermoelectric transport properties of nanostructured FeSb 2 and Ce-based heavy-fermions CeCu and CeAl 3

    Science.gov (United States)

    Pokharel, Mani R.

    the thermal conductivities of nanostructured FeSb2 samples 7. We find a notably large value for Kapitza length at low temperatures indicating the dominance of inter-grain thermal resistance over bulk thermal resistance in determining the thermal properties of FeSb 2. 1Huaizhou Zhao, Mani Pokharel, Gaohua Zhu, Shuo Chen, Kevin Lukas, Qing Jie,Cyril Opeil, Gang Chen, and Zhifeng Ren, Appl. Phys. Lett. 99, 163101 (2011). 2Mani Pokharel, Tulashi Dahal, Zhifeng Ren, and Cyril Opeil, Journal of Alloys and Compounds 609 (2014) 228-232. 3Mani Pokharel, Tulashi Dahal, Zhensong Ren, Peter Czajka, Stephen Wilson, Zhifeng Ren, and Cyril Opeil, Energy Conversion and Management, 87 (2014) 584-588. 4Mani Pokharel, Machhindra Koirala, Huaizhau Zhao, Zhifeng Ren, and Cyril Opeil, J. Low Temp. Phys., 176 (2014) 122-130. 5Mani Pokharel, Huaizhou Zhao, Shuo Chen, Kevin Lukas, Hui Wang, Cyril Opeil1, Gang Chen, and Zhifeng Ren, Nanotechnology 23 (2012) 505402. 6Mani Pokharel, Huaizhou Zhao, Kevin Lukas, Bogdan Mihaila, Zhifeng Ren, and Cyril Opeil, MRS Communications 3 (2013) 31-36. 7Mani Pokharel, Huaizhau Zhao, Zhifeng Ren, and Cyril Opeil, International Journal of Thermal Science, 71 (2013) 32-35.

  5. Psychometric properties of the Anxiety Inventory for Respiratory Disease in patients with COPD in China

    Directory of Open Access Journals (Sweden)

    Dong X

    2016-12-01

    Full Text Available Xiao-Yan Dong,1,* Lan Wang,1,* Yan-Xia Tao,1 Xiu-li Suo,2 Yue-Chuan Li,2 Fang Liu,1 Yue Zhao,1 Qing Zhang1 1School of Nursing, Tianjin Medical University, 2Department of Respiratory Care, Tianjin Chest Hospital, Tianjin, People’s Republic of China *These authors contributed equally to this work Background: Anxiety is a common comorbidity in patients with COPD in China, and it can significantly decrease patients’ quality of life. Almost all anxiety measurements contain somatic items that can overlap with symptoms of COPD and side effects of medicines, which can lead to bias in measuring anxiety in patients with COPD. Therefore, a brief and disease-specific non-somatic anxiety measurement scale, the Anxiety Inventory for Respiratory Disease (AIR, which has been developed and validated in its English version, is needed for patients with COPD in China.Methods: A two-center study was conducted in two tertiary hospitals in Tianjin, China. A total of 181 outpatients with COPD (mean age 67.21±8.10 years, 32.6% women, who met the inclusion and exclusion criteria, were enrolled in the study. Test–retest reliability was examined using intraclass correlation coefficients. The internal consistency was calculated by Cronbach’s α. Content validity was examined using the Content Validity Index (CVI, scale-level CVI/universal agreement, and scale-level CVI/average agreement (S-CVI/Ave. Besides, convergent validity and construct validity were also examined.Results: The AIR-C (AIR-Chinese version scale had high test–retest reliability (intraclass correlation coefficient =0.904 and internal consistency (Cronbach’s α=0.914; the content validity of the AIR-C scale was calculated by CVI, scale-level CVI/universal agreement, and S-CVI/Ave at values of 0.89–1, 0.90, and 0.98, respectively. Meanwhile, the AIR-C scale had good convergent validity, correlating with the Hospital Anxiety and Depression Scale-Anxiety (r=0.81, P<0.01, and there were

  6. Association between CD14 SNP -159 C/T and gastric cancer: an independent case–control study and an updated meta-analysis

    Directory of Open Access Journals (Sweden)

    Gong AM

    2016-07-01

    Full Text Available Ai-Min Gong,1,2,* Xin-Yuan Li,2,* Yi-Qiang Xie,1 Zhan-Dong Jia,3 Yuan-Xin Li,4 Yong-Yan Zou,5 Chang-Qing Xu,2,* Zhen-Yu Wang2,* 1Department of Internal Medicine of Traditional Chinese Medicine, Hainan Medical University, Hainan, 2Department of Pathophysiology, Harbin Medical University, Harbin, 3Department of Nephrology, Ningbo Tradition Chinese Medicine Hospital affiliated to Zhejiang Chinese Medical University, Ningbo, 4The Fifth Department of Acupuncture, 5Department of Nephrology, Jining Tradition Chinese Medicine Hospital, Jining, People’s Republic of China *These authors contributed equally to this work Purpose: The association between CD14 -159C/T polymorphism and the susceptibility to gastric cancer (GC has been reported. However, the results were inconclusive. In the present study, a case–control study and a meta-analysis were performed to assess the possible association between -159C/T in the CD14 gene and GC risk. Patients and methods: Relevant studies were searched in several databases including PubMed, Web of Science, EMBASE, Chinese National Knowledge Infrastructure database, and Wanfang database (last search was performed on December 30, 2015. In addition, a case–control study involving 164 GC cases and 169 controls was also performed in the analysis. Statistical analysis was performed by the software Revman5.3.Results: A total of ten published studies and the present case–control study involving 2,844 GC and 3,983 controls were included for the meta-analysis. The analysis result indicated that the T allele of CD14 -159C/T polymorphism did not confer risk for GC (in our study: [P=0.93]; in the meta-analysis: T vs 2N odds ratio =1.28 and 95% confidence interval (CI =0.95–1.24, [P=0.24]. However, we found a significant association in the recessive model (in our study: TT vs TC+CC [P=0.04]; in the meta-analysis: TT vs TC+CC odds ratio =1.12 and 95% CI =1.01–1.26, [P=0.04]. Furthermore, a subgroup analysis by ethnicity

  7. Psychometric properties of the Physical Activity Scale for the Elderly in Chinese patients with COPD

    Directory of Open Access Journals (Sweden)

    Tao YX

    2016-12-01

    Full Text Available Yan-xia Tao,1,* Lan Wang,1,* Xiao-yan Dong,1 Hong Zheng,2 Ya-shu Zheng,2 Xing-yue Tang,1 Yue Zhao,1 Qing Zhang1 1School of Nursing, Tianjin Medical University, 2Department of Respiratory Care, Tianjin First Center Hospital, Tianjin, People’s Republic of China *These authors contributed equally to this work Background: For patients with COPD, physical activity (PA is recommended as the core component of pulmonary rehabilitation, but there is lack of a validated questionnaire for assessing the PA effectively. Aim: To evaluate the reliability and validity of the Chinese version of Physical Activity Scale for the Elderly (PASE-C in patients with COPD. Methods: A cross-sectional study was conducted with 167 outpatients aged 60 years or older with COPD. Test-retest reliability and internal consistency were calculated by intraclass correlation coefficient (ICC and Cronbach’s coefficient α, respectively. Validity was evaluated by correlation with the International Physical Activity Questionnaire-Short (IPAQ-S, data of pedometer, Self-Efficacy for Managing Chronic Disease 6-Item Scale (SES6, Hospital Anxiety and Depression Scale (HADS, Medical Outcomes Study 36-Item Short Form Health Survey (SF-36, grip strength, and disease characteristics. Results: The PASE-C had an excellent seven-day test-retest reliability (ICC=0.98 and an acceptable internal consistency (Cronbach’s α=0.71. The content validity was supported by an item-content validity index, a scale-content validity index/universal agreement, and a scale-content validity index/average value of 0.70-1, 0.70, and 0.93, respectively. Concurrent validity was tested by correlation with IPAQ-S (r=0.651. Criterion validity was confirmed by correlation with the walking steps (r=0.611 and energy expenditure (r=0.493. For construct validity, PASE-C had correlations with SES6 (r=0.396, HADS for depression (r=-0.234, seven subscales of SF-36 (r=0.182-0.525, grip strength (r=0.341, and disease

  8. Globalization and Chinese Education in the Early 20th Century

    Science.gov (United States)

    Bailey, Paul J.

    2013-01-01

    With China's growing significance in the global economy ever more evident, studies in recent years have highlighted multiple aspects of China's "Globalization" (or global connections) that predate the contemporary period. This article focuses on educational reform in the late Qing and early Republic as a way of illuminating a significant…

  9. Studies of “emaciation ailment” in the Bactrian camel

    African Journals Online (AJOL)

    hope&shola

    2010-12-06

    Dec 6, 2010 ... 1Chong Qing University of Science and Technology, Chongqing 401331, China. 2Lanzhou Institute of Animal Sciences and Veterinary Pharmaceutics of Chinese Academy Agriculture Science, Lanzhou. 730050, China. .... heat of the graphite furnace allows the carbon in the graphite tube to combine with ...

  10. Detrital zircon and apatite fission track data in the Liaoxi basins ...

    Indian Academy of Sciences (India)

    Author Affiliations. Yi Yan1 Xiaoqiong Hu1 Ge Lin1 Weiliang Liu1 Zhengjiang Song2. Key Laboratory of Marginal Sea Geology, Guangzhou Institute of Geochemistry, Chinese Academy of Sciences, Wushan, Guangzhou, 510 640, P. R. China. Tou Tay Oilfield Development Company Limited DaQing, Heilongjiang, 151 300, ...

  11. Effect of recombinant human erythropoietin expressions of apoptosis ...

    African Journals Online (AJOL)

    Effect of recombinant human erythropoietin expressions of apoptosis genes in rats following traumatic brain injury. Xuesong Yuan1*, Xiaoxing Bian1, Wenfeng Wei1, Yin Tang2 and Qing Bao1. 1Department of Neurosurgery, 2Department of Pathology, The Affiliated Wujin Hospital of Jiangsu University, Changzhou. Jiangsu ...

  12. Author Details

    African Journals Online (AJOL)

    Wei, Yong-Qing. Vol 14, No 12 (2015) - Articles Effect of Thiazolidinedione Amide on Insulin Resistance, Creactive Protein and Endothelial Function in Young Women with Polycystic Ovary Syndrome Abstract PDF. ISSN: 1596-9827. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians ...

  13. Ideal shear strength and deformation behaviours of L10 TiAl from ...

    Indian Academy of Sciences (India)

    Author Affiliations. PING-YING TANG1 GUO-HUA HUANG1 QING-LIAN XIE1 JIAN-YING LI1. Key Laboratory of New Electric Functional Materials of Guangxi Colleges and Universities, Guangxi Teachers Education University, Nanning 530023, China ...

  14. DETECTION OF K-RAS AND P53 MUTATIONS IN SPUTUM SAMPLES OF LUNG CANCER PATIENTS USING LASER CAPTURE MICRODISSECTION MICROSCOPE AND MUTATION ANALYSIS

    Science.gov (United States)

    Detection of K-ras and p53 Mutations in Sputum Samples of Lung Cancer Patients Using Laser Capture Microdissection Microscope and Mutation AnalysisPhouthone Keohavong a,*, Wei-Min Gao a, Kui-Cheng Zheng a, Hussam Mady b, Qing Lan c, Mona Melhem b, and Judy Mumford d.<...

  15. 'Kinyarwanda doesn't have a place in communication at our schools ...

    African Journals Online (AJOL)

    ahavugimana

    English in Rwandan schools. Language is more than a tool for communication. Language has been commonly defined as 'a tool or a vehicle for communication' (see Locke 2002; Turuk 2008; Xiao Qing 2000). While we agree to the fact that the primary function of language is communication, this definition may bring some ...

  16. Evaluating "Cat Country": The Humor within Satire

    Science.gov (United States)

    Chang, Chung-chien Karen

    2010-01-01

    Satire, as a mode, is not frequently employed in Chinese narratives. "Cat Country," or "Mao Cheng Ji," written by Lao She (pen name of Shu Qing Chun, 1898--1966) has come under much attack of its literary values. Whereas most critics have no doubt that this work sets out to satirize China through the portrayal of a society of…

  17. The earlier identification of the seedless characteristic of the wampee

    African Journals Online (AJOL)

    Jane

    2010-12-13

    Dec 13, 2010 ... ting the fruit with sugar (Morton, 1987; Pratheung et al.,. 2007). The leaves, roots ... al., 1991). In an effort to identify molecular marker linked to seedless gene, we conducted BSA using several commercial cultivars. Hybrid progeny was identified by .... L and Qing. Y. G of the South China Agricultural Univer-.

  18. Effects of size on mass density and its influence on mechanical and ...

    Indian Academy of Sciences (India)

    Logo of the Indian Academy of Sciences. Indian Academy of Sciences ... QING JIANG2 MUSTAFA SAEED OMAR1. Department of Physics, College of Science, Salahaddin-Erbil University, Erbil 31019, Kurdistan Region, Iraq; Department of Material Science and Engineering, Jilin University, Changchun 130022, China ...

  19. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    pp 379-388 Articles. Isolation and characterization of a gene encoding a polyethylene glycol-induced cysteine protease in common wheat · Qing-Wei ... pp 405-413 Articles. Identification, tissue distribution and evaluation of brain neuropeptide Y gene expression in the Brazilian flounder Paralichthys orbignyanus · Vinicius F ...

  20. Design of the OffWindChina 5 MW Wind Turbine Rotor

    DEFF Research Database (Denmark)

    Sun, Zhenye; Sessarego, Matias; Chen, Jin

    2017-01-01

    The current article describes the conceptual design of a rotor for a 5 MW machine situated at an offshore site in China (OffWindChina). The OffWindChina 5 MW rotor design work was divided into two parts between the Technical University of Denmark (DTU) and the Chong Qing University (CQU). The two...

  1. Your Paper's Title Starts Here:

    African Journals Online (AJOL)

    Hans Neber-Aeschbacher

    2012-06-05

    Jun 5, 2012 ... Petroleum-degrading bacterium JY6 was isolated from petroleum-contaminated soils in DaQing oil field. It was identified as Bacillus cereus based on its morphological, physiological and biochemical characteristics, and analysis of its 16SrRNA gene. Biodegradation function of petroleum and oil.

  2. Unity in variety

    Directory of Open Access Journals (Sweden)

    Anna G. Alyabyeva

    2016-08-01

    Full Text Available Review: Karelina E.K. Istoriya tuvinskoy muzyki ot padenia dinastiyi Tsin i do nashih dney (History of Tuvan music from the downfall of the Qing Dynasty till present day: research / scientific editor Doctor of Art V.N. Yunusov. Moscow: Composer publishing house, 2009. 552 p.

  3. Performing "Chinese-ness" in Singkawang

    NARCIS (Netherlands)

    Ong, C.E.; Ormond, M.E.; Sulianti, Dian

    2017-01-01

    Through an examination of two festivals – Qing Ming and Cap Go Meh – in the town of Singkawang in Indonesian Borneo (Kalimantan), we show how Singkawang-bound Chinese Indonesian tourists and their Singkawang-based relatives produce a diasporic heritage network through ‘moorings’ generated by both

  4. Investigation of properties of rare earth complexes with dibromo-p ...

    Indian Academy of Sciences (India)

    Author Affiliations. Hong-Wen Gao1 Fa-Shui Hong2 Qing-Song Ye2. School of Chemistry and Chemical Engineering, Anhui University, Hefei 230039, P. R. China; Department of Biological Science, Huaibei Coal Teachers College, Huaibei 235000, P. R. China ...

  5. Designing Robust and Resilient Tactical MANETs

    Science.gov (United States)

    2014-09-25

    Multipath Wireless Network, IEEE ISIT 2012. 01-JUL-12, . : , Tzong-Chen Wu, Chia-Hsin Owen Chen, Chung-Wei Chen, Cynthia Kuo, Yan-Hao Lai, Jonathan...Communications. 01-MAY-08, . : , Qing Li , Meiyuan Zhao , Jesse Walker, Yih-Chun Hu, Adrian Perrig, Wade Trappe. SEAR: A Secure Efficient Ad Hoc On Demand Routing

  6. Protein expression of sensory and motor nerves

    National Research Council Canada - National Science Library

    Zhiwu Ren Yu Wang Jiang Peng Li Zhang Wenjing Xu Xiangdang Liang Qing Zhao Shibi Lu

    2012-01-01

    ... of sensory and motor nerves Two.dimensional gel electrophoresis and mass spectrometry*★★☆Zhiwu Ren’,2 Yu Wang’,Jiang Peng’,Li Zhang’,Wenjing Xu’,Xiangdang Liang。,Qing...

  7. 1981 Annual Report of the Center for Naval Analyses.

    Science.gov (United States)

    1981-01-01

    has studied such varied matters as problems of health, education, urban crime, library planning, and national policy toward ocean resource development...1279-1368), the Ming (1368-1644), and the Qing or Manchu (1644-191 1)-tried to meet the challenges posed by sea travel, ocean trade, and foreign ideas

  8. Urbanization in China, ca. 1100–1900

    NARCIS (Netherlands)

    Xu, Y.; van Leeuwen, B.; van Zanden, J.L.

    2015-01-01

    This paper presents new estimates of the development of the urban population andthe urbanization ratio for the period spanning the Song and late Qing dynasties. Urbanizationis viewed, as in much of the economic historical literature on the topic, as an indirectindicator of economic development and

  9. JPRS Report, Near East & South Asia, Bangladesh

    Science.gov (United States)

    1991-08-13

    Qing Palace The Federation Chairman said a total of five lakh people Prime Minister Begum Khaleda Zia on Thursday morning got their cataract operated...ment initiatives for the welfare of the people. Last year, non- monetized channel; the quantity may have to be only $1.8 billion was pledged; this year

  10. 78 FR 55772 - Culturally Significant Object Imported for Exhibition Determinations: “Beauty Revealed: Images of...

    Science.gov (United States)

    2013-09-11

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Culturally Significant Object Imported for Exhibition Determinations: ``Beauty Revealed: Images of Women in...: Images of Women in Qing Dynasty Chinese Painting,'' imported from abroad for temporary exhibition within...

  11. Microorganisms from hands of traditional Chinese medical doctors ...

    African Journals Online (AJOL)

    Microorganisms from hands of traditional Chinese medical doctors in a central hospital environment. Ye Sun, LiXiang Yu, Min Sun, YanQing Tong. Abstract. Background: In a central hospital, the heavy clinical workload makes one to overlook its hazard to health and can to a large extent promote the transmission of ...

  12. Synthetic Polypeptide Derived from Viral Macrophage Inflammatory ...

    African Journals Online (AJOL)

    Bo Xu, Peng Tian, Gui-Jie An, Sha Liu, Xiu-Ying Li, Han-Xiao Sun*, Jing-Gung. Zhou, Qing Ding and Pi-Jin Wei. Institute of Genomic Medicine, College of Pharmacy, Jinan University, Guangzhou 510632, China. *For correspondence: Email: sunhx718@163.com; Tel: +86 - 020-38375022. Received: 18 March 2014. Revised ...

  13. Purifying capability, enzyme activity, and nitrification potentials in December in integrated vertical flow constructed wetland with earthworms and different substrates.

    Science.gov (United States)

    Xu, Defu; Gu, Jiaru; Li, Yingxue; Zhang, Yu; Howard, Alan; Guan, Yidong; Li, Jiuhai; Xu, Hui

    2016-01-01

    The response of purifying capability, enzyme activity, nitrification potentials, and total number of bacteria in the rhizosphere in December to wetland plants, substrates, and earthworms was investigated in integrated vertical flow constructed wetlands (IVFCW). The removal efficiency of total nitrogen (TN), NH4-N, chemical oxygen demand (COD), and total phosphorus (TP) was increased when earthworms were added into IVFCW. A significantly average removal efficiency of N in IVFCW that employed river sand as substrate and in IVFCW that employed a mixture of river sand and Qing sand as substrate was not found. However, the average removal efficiency of P was higher in IVFCW with a mixture of river sand and Qing sand as substrate than in IVFCW with river sand as substrate. Invertase activity in December was higher in IVFCW that used a mixture of river sand and Qing sand as substrate than in IVFCW which used only river sand as substrate. However, urease activity, nitrification potential, and total number of bacteria in December was higher in IVFCW that employed river sand as substrate than in IVFCW with a mixture of river sand and Qing sand as substrate. The addition of earthworms into the integrated vertical flow constructed wetland increased the above-ground biomass, enzyme activity (catalase, urease, and invertase), nitrification potentials, and total number of bacteria in December. The above-ground biomass of wetland plants was significantly positively correlated with urease and nitrification potentials (p nitrification potentials in December, which resulted in improving purifying capability.

  14. Browse Author Index

    African Journals Online (AJOL)

    Meléndez-Camargo, ME · Mellal, Abdallah Abu · Memon, Abdul Hakeem · Memon, AH · Men, Bo · Mena-Rejón, Gonzalo J. Menan, HE · Mendes, Rosemairy L · Meng, Haitao · Meng, OL · Meng, Ping · Meng, Qing-hua · Meng, W · Meng, X · Meng, XH 3801 - 3850 of 6992 Items >>.

  15. Tropical Journal of Pharmaceutical Research - Vol 15, No 5 (2016)

    African Journals Online (AJOL)

    Clinical effects of sirolimus treatment in patients with increased serum creatinine levels after renal transplant · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. Zhen-Hong Pan, Yan-Xuan Zhang, Jun Fang, Qing-Shan Qu, Xin Jiang, Ming Li, 1077-1081.

  16. AI-PING ZHOU

    Indian Academy of Sciences (India)

    Home; Journals; Pramana – Journal of Physics. AI-PING ZHOU. Articles written in Pramana – Journal of Physics. Volume 89 Issue 6 December 2017 pp 82 Research Article. Zakharov equations for viscous flow and their use in the blood clot formation · AI-PING ZHOU XIAO-QING LI · More Details Abstract Fulltext PDF.

  17. Superplasticity and Superplastic Forming: Proceedings of an International Conference on Superplasticity and Superplastic Forming Held in Blaine, Washington on 1-4 August 1988

    Science.gov (United States)

    1988-01-01

    GBD density in random boundaries tends to a stationary value, while in twin boundaries the GBS accumulation takes place. That is why a greater number...Shanghai Jiao Tong University, Shanghai 200030, The People’s Republic of China Abstract In order to determine the role of grain boundary dislocations ( GBDs ...during superplastic deformation, the GBD structures in a fine grained super- duralumin alloy have been investigated by means of transmission electron

  18. OSA Imaging and Applied Optics Congress Support

    Science.gov (United States)

    2017-02-16

    560 Andreas Erdmann Fraunhofer Institute for Integrated $230 Systems and Device Technology IlSB Moti Fridman Bar Ilan University $230 A mal...Society of America, 2016), paper CT4C.3. D. Marx and B. Kern , "Phase Retrieval Implementation for the WFIRST Coronagraph Development Testbed," in...Holographic Display using Digital Micro-mirror Device ," in Imaging and Applied Optics 2016, (Optical Society of America, 2016), paper JW4A.43. S. JIAO

  19. Selective review and commentary on emerging pharmacotherapies for opioid addiction

    OpenAIRE

    Ling, Walter; Mooney, Larissa; Zhao, Min; Nielsen, Suzanne; Torrington, Matthew; Miotto, Karen

    2011-01-01

    Walter Ling1, Larissa Mooney1, Min Zhao2, Suzanne Nielsen1, Matthew Torrington1, Karen Miotto1 1Integrated Substance Abuse Programs, University of California, Los Angeles, CA, USA; 2Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China Abstract: Pharmacotherapies for opioid addiction under active development in the US include lofexidine (primarily for managing withdrawal symptoms) and Probuphine®, a distinctive mode of delivering buprenorphi...

  20. Academic rankings: an approach to a Portuguese ranking

    OpenAIRE

    Bernardino, Pedro; Marques,Rui

    2009-01-01

    The academic rankings are a controversial subject in higher education. However, despite all the criticism, academic rankings are here to stay and more and more different stakeholders use rankings to obtain information about the institutions’ performance. The two most well-known rankings, The Times and the Shanghai Jiao Tong University rankings have different methodologies. The Times ranking is based on peer review, whereas the Shanghai ranking has only quantitative indicators and is mainly ba...

  1. Adipose inflammation: cause or consequence of obesity-related insulin resistance

    OpenAIRE

    Haiyan Xu; Ping Jiao

    2008-01-01

    Ping Jiao, Haiyan XuHallett Center for Diabetes and Endocrinology, Brown Medical School, Providence, RI, USAAbstract: Obesity constitutes a critical risk factor for the development of many life threatening diseases, particularly insulin resistance and type 2 diabetes. Adipose tissue plays an important role in regulating whole body energy homeostatsis and obesity-related insulin resistance. Inflammation has been commonly linked to insulin resistance. Recent studies demonstrated that adipose ti...

  2. A new species of gall midge (Diptera: Cecidomyiidae) attacking jujube, Ziziphus jujuba in China.

    Science.gov (United States)

    Jiao, Ke-Long; Han, Pei-Jin; Yang, Ming-Lu; Xiong, Ren-Ci; Wang, Yuan-Hong; Bu, Wen-Jun

    2017-03-28

    Dasineura jujubifolia Jiao & Bu, sp. nov., a gall midge feeding on jujube, Ziziphus jujuba Miller (Rhamnaceae), a fruit tree cultivated extensively in large areas of China, is described and illustrated based on specimens collected from Alar (Xinjiang, China). The new gall midge species causes rolled leaf galls on Ziziphus jujuba in Northwestern China. Brief notes on the biology of the jujube gall midge are given.

  3. Theoretical study of aromaticity in inorganic tetramer clusters

    Indian Academy of Sciences (India)

    ... Jiao H, Hommes N V E,. Malkina V G and Malkina O L 1997 J. Am. Chem. Soc. 119 12669. 36. (a) Becke A D 1998 Phys. Rev. A38 3098; (b) Lee C,. Yang W and Parr R G 1988 Phys. Rev. B37 785. 37. Schmidt W et al 1993 J. Comput. Chem. 14 1347. 38. Frisch M J et al 1998 GAUSSIAN-98, Gaussian Inc,. Pittsburgh, PA.

  4. New Epigenetic Therapeutic Intervention for Metastatic Breast Cancer

    Science.gov (United States)

    2017-04-01

    AWARD NUMBER: W81XWH-15-1-0043 TITLE:New Epigenetic Therapeutic Intervention for Metastatic Breast Cancer PRINCIPAL INVESTIGATOR: Ming-Ming Zhou... Nutritional Sciences, The University of Kentucky, College of Medicine, Lexington, Kentucky 40506, USA. 2Markey Cancer Center, The University of Kentucky...40506, USA. 9 Key Laboratory of Cell Differentiation and Apoptosis of Chinese Minister of Education , Shanghai Jiao Tong University School of Medicine

  5. The comparison of different daidzein-PLGA nanoparticles in increasing its oral bioavailability

    OpenAIRE

    Ma YR; Zhao XY; Li J; Shen Q

    2012-01-01

    Yiran Ma, Xinyi Zhao, Jian Li, Qi ShenSchool of Pharmacy, Shanghai Jiao Tong University, Shanghai, ChinaAbstract: The aim of this research was to increase the oral bioavailability of daidzein by the formulations of poly(lactic-co-glycolic) acid (PLGA) nanoparticles loaded with daidzein. Amongst the various traditional and novel techniques of preparing daidzein-loaded PLGA nanoparticles, daidzein-loaded phospholipid complexes PLGA nanoparticles and daidzein-loaded cyclodextrin inclusion comple...

  6. Ranking and Mapping the Contributions by Overseas Chinese Strategy Scholars

    DEFF Research Database (Denmark)

    Li, Weiwen; Li, Peter Ping; Shu, Cheng

    2015-01-01

    The authors comment on an article by H. Jiao and colleagues regarding development of a ranking of overseas Chines strategy scholars in terms of their contributions to the strategy research. Topics include selection of 24 business journals ranked by the University of Texas at Dallas...... for their research; identifying authors who had published articles in periodicals such as "Management and Organization Review;" and development of a coding protocol and discussing coding procedure.....

  7. Ultracold Atoms in Optical Lattices

    Science.gov (United States)

    2006-08-15

    Rousset, G. et al. Design of the Nasmyth adaptive optics system ( NAOS ) of the VLT. Proc. SPIE 3353 (Adaptive Optics Technology), 508–516 (1998). 11...ESO) in Chile. We thank the teams who developed and constructed the near-infrared camera CONICA and the AO system NAOS , and especially their...Shanghai Jiao Tong University, 800 Dongchuan Road, Shanghai, 200240, China 2Bussan Nanotech Research Institute, 2-1 Koyadai, Tsukuba, Ibaraki 305-0074

  8. The Role of SIRT1 In Breast Cancer Stem Cells

    Science.gov (United States)

    2016-09-01

    tumorigenesis and 18 resistance to chemotherapy in hepatocellular carcinoma and its expression predicts poor prognosis. Ann Surg Oncol. 2012;19:2011-9...results. Furthermore, specifically knock down SIRT1 expression with SIRT1 small inhibitor RNA significantly reduced SOX-2 protein and slightly...SJ, et al. Expression of DBC1 and SIRT1 is associated with poor prognosis for breast carcinoma . Hum Pathol 2011;42:204-13. 26. Chen X, Sun K, Jiao S

  9. マレーシアにおける華語紙をめぐる政治 : MCA による『南洋商報』買収事件に注目して

    OpenAIRE

    伊賀, 司

    2010-01-01

    This study examines the politics of Chinese media in Malaysia, focusing on a case study of the Nanyang takeover issue. In June 2001, the Malaysian Chinese Association (MCA), one of the major component parties of the Barisan Nasional (BN) ruling coalition, took over a Chinese daily, Nanyang Siang Pau, in the face of vehement opposition from the United Chinese School Committees Association of Malaysia (Dong Jiao Zong), famous Chinese writers, and even a part of MCA. Five years after the takeove...

  10. Monitoring cancer stem cells: insights into clinical oncology

    Directory of Open Access Journals (Sweden)

    Lin SC

    2016-02-01

    Full Text Available ShuChen Lin,1,* YingChun Xu,2,* ZhiHua Gan,1 Kun Han,1 HaiYan Hu,3 Yang Yao,3 MingZhu Huang,4 DaLiu Min1 1Department of Oncology, Shanghai Sixth People’s Hospital East Campus, Shanghai Jiao Tong University, 2Department of Oncology, Renji Hospital, Shanghai Jiao Tong University, 3Department of Oncology, The Sixth People’s Hospital, Shanghai Jiao Tong University, 4Department of Medical Oncology, Cancer Hospital of Fudan University, Shanghai, People’s Republic of China *These authors contributed equally to this work Abstract: Cancer stem cells (CSCs are a small, characteristically distinctive subset of tumor cells responsible for tumor initiation and progression. Several treatment modalities, such as surgery, glycolytic inhibition, driving CSC proliferation, immunotherapy, and hypofractionated radiotherapy, may have the potential to eradicate CSCs. We propose that monitoring CSCs is important in clinical oncology as CSC populations may reflect true treatment response and assist with managing treatment strategies, such as defining optimal chemotherapy cycles, permitting pretreatment cancer surveillance, conducting a comprehensive treatment plan, modifying radiation treatment, and deploying rechallenge chemotherapy. Then, we describe methods for monitoring CSCs. Keywords: cancer stem cells, glycolytic inhibition, watchful waiting, rechallenge, immunotherapy

  11. Advances with microRNAs in Parkinson’s disease research

    Directory of Open Access Journals (Sweden)

    Ma L

    2013-10-01

    Full Text Available Liuqing Ma,1,2,* Liangming Wei,3,* Fei Wu,2,* Zhenhua Hu,2 Zhenguo Liu,1 Weien Yuan2 1Department of Neurology, Xinhua Hospital affiliated with Shanghai JiaoTong University School of Medicine, Shanghai, People’s Republic of China; 2School of Pharmacy, Shanghai JiaoTong University, Shanghai, People’s Republic of China; 3Research Institute of Micro/Nano Science and Technology, Shanghai JiaoTong University, Shanghai, People’s Republic of China *These authors contributed equally to this work Abstract: Parkinson’s disease (PD is the second-most common age-dependent neurodegenerative disorder and is caused by severe degeneration of dopaminergic neurons in the substantia nigra pars compacta. Unfortunately, current treatment only targets symptoms and involves dopamine replacement therapy, which does not counteract progressive degeneration. MicroRNAs (miRNAs are a class of small RNA molecules implicated in post-transcriptional regulation of gene expression during development. Recent studies show that miRNAs are playing an important role in the pathophysiology of PD. miRNA-based therapy is a powerful tool with which to study gene function, investigate the mechanism of the disease, and validate drug targets. In this review, we focus on the recent advances of the use of miRNAs in the pathogenesis of PD. Keywords: miRNA, α-synuclein, LRRK2, miRNA-based therapy, pathophysiology

  12. synthetic approaches

    African Journals Online (AJOL)

    Dr Mdachi

    Avances en Quimica 8: 145-151. Chen J, Zhou L, Tan CK and Yeung Y-Y. 2012 An Enantioselective Approach toward 3,4-Dihydroisocoumarin through the Bromocyclization of Styrene-type. Carboxylic Acids. J. Org. Chem.77: 999-. 1009. Chen P-Y, Wang Y-F, Chen L-Y, Wang G-. L and Wang E-C 2013 Reaction of o-.

  13. Consumer evaluation of imported organic food products in emerging economies in Asia

    OpenAIRE

    Pedersen, Susanne; Aschemann-Witzel, Jessica; Thøgersen, John

    2017-01-01

    Consumer evaluation of imported organic food products in emerging economies in Asia Introduction Consumers in emerging economies such as Thailand and China have started to demand organic food products – mainly due to food safety reasons (Ortega, Wang, Wu, & Hong, 2015; Roitner-Schobesberger, Darnhofer, Somsook, & Vogl, 2008; C. L. Wang, Li, Barnes, & Ahn, 2012; O. Wang, De Steur, Gellynck, & Verbeke, 2015). However, since the domestic organic markets are still not well-establi...

  14. Characteristics and management of Enterobacteriaceae harboring ...

    African Journals Online (AJOL)

    Cite as: Pang F, Jia X-q, Song Z-z, Li Yh, Wang B, Zhao Q-g, Wang C-x, Zhang Y, Wang L-x. Characteristics and management of Enterobacteriaceae harboring IMP-4 or IMP-8 carbapenemase in a tertiary hospital. Afri Health Sci. 2016;16(1): 153-161. http://dx.doi.org/10.4314/ahs.v16i1.21. * Corresponding authors:.

  15. Acta Aerodynamica Sinica,

    Science.gov (United States)

    1986-11-03

    Xttack; by Wang Zixing and Wu Genxing .............................. 110’) On the Investigation of Separated Flow in the lase,-by Bian Yinqui and Dong...1984). 109 Effect of Winglet on Spatial Vortex of a Solid in Rotation at /49 High Angle of Attack Wang Zixing and Wu Genxing (Nanjing Aeronautical...attract the separation vortex of the slender body. 120 References [1] Wu Genxing and Wang Zixing, Symposium of China Society of Mechanics on "Flow

  16. 76 FR 6135 - Ocean Transportation Intermediary License Applicants

    Science.gov (United States)

    2011-02-03

    ..., Inc. (NVO), 17756 Palo Verde Avenue, Cerritos, CA 90703, Officer: James Wang, CFO/CEO/Secretary.... Grannell, President/CEO (Qualifying Individual), Michael Kuhn, Vice President, Sales & Marketing...

  17. 專論/台灣圖書館史數位圖書館建構之研究/王梅玲;蔡明月;陳志銘;柯雲娥;蔡佳縈;陳勇汀;林怡甄 | A Digital Library Pilot Study on Taiwan Libraries' History / Mei-Ling Wang; Ming-Yueh Tsay; Chih-Ming Chen; Yun-Er Ke; Chia-Ying Tsai; Yong-Ting Chen; Yi-Jen Lin

    Directory of Open Access Journals (Sweden)

    王梅玲、蔡明月、陳志銘、柯雲娥、蔡佳縈、陳勇汀、林怡甄

    2008-04-01

    Full Text Available

    圖書館是保存與詮釋人類文化重要的機構,1990 年代開始,網際網路的進步,促成數位圖書館蓬勃發展,有人預測它就是未來的圖書館,因此,圖書館界與教育界積極參與相關研究。台灣地區歷經日據時期、重建 時期、成長時期及茁壯時期四階段,建設許多圖書館,有其豐富的主題與素材值得發展成為數位圖書館。政治大學圖書資訊與檔案學研究所有鑑於此,提出「『台灣 百無圖書館史』數位圖書館」的構想,並獲得政大「發展國際一流大學及頂尖研究中心計畫」經費支持。本研究計畫目的包括:(1探索以台彎圖書館事業史為主 題的數位圖書館建構模式;(2建構數位圖書館以支援圖書資訊學教育與研究;(3研訂圖書館事業史料文獻的Metadata與數位資料格式;(4將圖 書文獻與文物數位化以建構數位館藏;(5發展數位圖書館系統與技術;(6研發數位圖書館網站的瀏覽與檢索功能;(7探討數位圖書館支援數位學習的模 式。計畫成果共研訂六種 Metadata標準:建置746筆數位化資料;以Dspace系統平台,依據需求設計台灣百年圖書館史系統架構與網站,最後提出結論與建議。

    Libraries are important social institutions that preserve and communicate human culture and knowledge. From the beginning of 1990s, the digital library has grown up rapidly based on the progress of the Internet. Libraries and educational institutions should be actively involved in digital library research and development. The Taiwan libraries’ history can be divided into four stages: Japanese occupation period, reconstruction period, growth period and strong period. In these processes, many events and libraries with rich materials that can be developed into a digital library. Graduate Institute of Library, Information and Archival Studies, National Chengchi University, planned the Digital Library Pilot Study on Taiwan Libraries’ History and got the university support. The pilot study objectives include: (1 exploring the digital library model on Taiwan libraries' history; (2 constructing digital library to support education and research in information and library science; (3 developing Metadata standards of library documents and heritage; (4 digitalizing documents and heritage to build digital collections (5 developing digital library systems and technology; (6 researching browsing and search functions of the digital library; (7 exploring the model of the digital library supports e-learning. In this pilot study, we developed six Metadata standards, built 746 digital resources, constructed a digital library system and web site, and proposed the conclusions and suggestions finally.

    頁次:15-38

  18. Erotic Enclaves and Contested Beds: Gardens in Pu Songling’s Chuanqi Tales

    Directory of Open Access Journals (Sweden)

    Lei Jin

    2015-02-01

    Full Text Available Abstract:             This article examines the literary garden depicted by Pu Songling (1640-1715 in his' Liaozhai zhiyi '聊齋誌異 (Liaozhai's records of the strange; 1766. These enchanted, deserted, and haunted gardens function as metaphors for the contested ground on which some key Ming-Qing intellectual issues are debated. The article examines Pu’s depiction of 'qing'情,an important concept reflecting the philosophical and literary trends of the time, and shows that in the process of constructing literary gardens, Pu challenges the intellectual issues of his time and dissolves the boundaries between normal and abnormal, reality and ideal, death and life, and order and disorder.

  19. Artemisinins from folklore to modern medicine--transforming an herbal extract to life-saving drugs.

    Science.gov (United States)

    Weina, P J

    2008-06-01

    The history of the artemisinins from Ge Hong in China during the 4th century, to the re-discovery of the qing hao derivatives in the 1970s, to the explosion of artemisinin derivatives and combinations throughout the world today is a fascinating story. The central and underappreciated role of the United States Army's 'drug company' known as the Division of Experimental Therapeutics at the Walter Reed Army Institute of Research is a story worth relating. From being the first group outside China to extract the active component of qing hao, to leading the work on neurotoxicity of the class in animals, to bringing a Good Manufacturing Practices intravenous formulation to the worldwide market is traced.

  20. Pattern of change in histone 3 lysine 9 acetylation and histone ...

    Indian Academy of Sciences (India)

    Pattern of change in histone 3 lysine 9 acetylation and histone deacetylases in development of zebrafish embryo. Yanning Li Junxia Wang Ying Xie Shufeng Liu Ye ... Wang1 Ying Xie1 Shufeng Liu1 Ye Tian1. Hebei Key Lab of Laboratory Animal, Hebei Medical University, Shijiazhuang 050017, People's Republic of China ...

  1. Journal of Genetics | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    pp 545-550 RESEARCH ARTICLE. Changes of host DNA methylation in domestic chickens infected with Salmonella enterica · FEI WANG JIANCHAO LI QINGHE LI RANRAN LIU MAIQING ZHENG QIAO WANG JIE WEN GUIPING ZHAO · More Details Abstract Fulltext PDF. Cytosine methylation is an effectiveway to ...

  2. Straightforward synthesis of hyperbranched polymer/graphene ...

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science; Volume 35; Issue 5. Straightforward synthesis of hyperbranched polymer/graphene nanocomposites from graphite oxide via in situ grafting from approach. Qiuhong Xu Yiwen Gong Yuan Fang Guohua Jiang Yin Wang Xinke Sun Rijing Wang. Volume 35 Issue 5 October 2012 ...

  3. In vitro pharmacokinetics of sirolimus-coated stent for tracheal stenosis

    African Journals Online (AJOL)

    In vitro pharmacokinetics of sirolimus-coated stent for tracheal stenosis. Shanzuan Wang, Zhengxian Chen, Qunying Lin, Qingyu Lin, Yumei Geng, Suwang Wang. Abstract. Purpose: To investigate the in vitro pharmacokinetics of sirolimus-coated stent for tracheal stenosis. Methods: Naked nickel titanium alloy stent was ...

  4. Optimization of multi-response dynamic systems integrating multiple ...

    African Journals Online (AJOL)

    2016), (2) multiple attribute decision making (MADM) methods based approaches (Tong et al., 2004; Wang and Tong, 2005;. Wang ... the response variables and control factors remain unknown, and therefore, the engineers fail to gain knowledge of professional .... and multiple criteria evaluation of the grey relation model.

  5. Safety of Thyroidectomy at a rural District Hospital in Kenya

    African Journals Online (AJOL)

    2010-01-16

    Jan 16, 2010 ... 55(10):693-702. 12. Sosa JA, Mehta PJ, Wang TS et al. A population-based study of outcomes from thyroidectomy in aging Americans: at what cost? J Am Coll Surg.2008 Jun;206(3):1097-105. 13. Sosa JA, Mehta PJ, Wang TS, et al. Racial disparities in clinical and economic outcomes from thyroidectomy.

  6. Disease: H01073 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available unistically pathogenic for humans. Shewanella infection is associated with a wide clinical spectrum and soft...565779 (description, env_factor) Tsai MS, You HL, Tang YF, Liu JW Shewanella soft...iption, env_factor) Chen YS, Liu YC, Yen MY, Wang JH, Wang JH, Wann SR, Cheng DL Skin and soft-tissue manife

  7. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Volume 31 Issue 2 April 2008 pp 193-195 Nanomaterials. Mesoscale organization of CuO nanoslices: Formation of sphere · Jun Wang Shunxiao Zhang ... Volume 31 Issue 4 August 2008 pp 597-601 Nanomaterials. ZnO nanostructured microspheres and grown structures by thermal treatment · Jun Wang Shunxiao Zhang ...

  8. Lp-dual affine surface area forms of Busemann–Petty type problems

    Indian Academy of Sciences (India)

    Associated with the notion of L p -intersection body which was defined by Haberl, we research L p -dual affine surface area forms of Busemann–Petty type problems. Author Affiliations. Jianye Wang1 Weidong Wang1. Department of Mathematics, China Three Gorges University, Yichang 443002, China. Dates. Manuscript ...

  9. Zingiber officinale cDNA cloning and characterization of a mannose ...

    Indian Academy of Sciences (India)

    Unknown

    Contribution of root respiration to soil respiration in a C3/C4 mixed grassland. 507. Wang Wenbing. Cloning and sequence analysis of the Antheraea pernyi nu- cleopolyhedrovirus gp64 gene. 605. Wang Zhaoyu. Enhancement of resistance to aphids by introducing the snow- drop lectin gene gna into maize plants. 627.

  10. T Cell Gene Therapy to Eradicate Disseminated Breast Cancers

    Science.gov (United States)

    2012-05-01

    and albumin to quantitate absolute white blood cell (WBC) numbers (5-accatgcttttcagctctgg-3/5-tctgcatggaaggtgaatgt-3, 81-bp). Amplifications were at... eggs , most of which were infertile. Hands-on Research Techniques Immunology experiments, mouse model, and biomedical...5. Xiuyang Guo, Liang Dong, Shengpeng Wang, Tingqing Guo, Jianyang Wang, and Changde Lu (2004). Introduction of Foreign Genes into Silkworm Eggs

  11. Two new species of Megistophylla Burmeister (Coleoptera: Scarabaeidae: Melolonthinae) from Taiwan, with notes on the genus.

    Science.gov (United States)

    Li, Chun-Lin; Yang, Ping-Shih; Wang, Chuan-Chan

    2016-06-17

    The genus Megistophylla (Coleoptera: Scarabaeidae: Melolonthinae) was first reported from Taiwan with the descriptions and illustrations of two new species, Megistophylla formosana Wang & Li, new species () and Megistophylla xitoui Li & Wang, new species (). An annotated checklist and modified key for the species in the genus are provided. The information in checklist for each species includes: literature review, synonymy, distribution, and type locality.

  12. Fertigation with domestic wastewater: Uses and implications

    African Journals Online (AJOL)

    Jose Geraldo

    2016-05-18

    May 18, 2016 ... serious problems in ponds, rivers and seas (Wang and. Wang, 2009). Alternatively, to avoid the accumulation of nutrients in the soil, Thongtha et al. ... Smith et al., 2010). In exchange the plant provides carbohydrates from photosynthesis for AMF (Smith et al.,. 2010). The AMFs contributes to the adaptation ...

  13. A new record and two new species of Cryptochironomus Kieffer, 1918 from China (Diptera, Chironomidae).

    Science.gov (United States)

    Yan, Chuncai; Zhao, Guangjun; Liu, Ting; Guo, Qin; Hou, Ziyuan; Wang, Xinhua; Pan, Baoping

    2016-12-19

    Two new species of the genus Cryptochironomus Kieffer, C. maculus Yan & Wang sp. n. and C. protuberans Yan & Wang sp. n. are described and illustrated as adult males. C. albofasciatus (Staeger) is recorded from China for the first time. A key to the males of Cryptochironomus in China is presented and generic diagnosis is emended.

  14. Two new and one newly recorded species of Polypedilum Kieffer 1912 with DNA barcodes from Oriental China (Chironomidae: Diptera).

    Science.gov (United States)

    Yan, Chuncai; Song, Chao; Liu, Ting; Zhao, Guangjun; Hou, Ziyuan; Cao, Wei; Wang, Xinhua

    2017-03-02

    Polypedilum (Tripodura) enshiense Song & Wang sp. n. and P. (Tripodura) jianfengense Song & Wang sp. n. are described and illustrated as male imagines from China. P. (Uresipedilum) paraconvictum Yamamoto, Yamamoto & Hirowatari, 2016 is recorded from China for the first time. Cytochrome coxidase subunit I (COI) sequence of above species are uploaded to Barcode of Life Data Systems (BOLD).

  15. Stability of organic matter in soils of the Belgium Loess Belt upon erosion and deposition

    NARCIS (Netherlands)

    Wang, X.; Cammeraat, E.; Wang, Z.; Govers, G.; Kalbitz, K.

    2011-01-01

    Stability of organic matter in soils of the Belgium Loess Belt upon erosion and deposition X. Wang, L.H. Cammeraat, Z. Wang, G. Govers, K. Kalbitz. Abstract: Soil erosion has significant impacts on terrestrial C dynamics, which removes C from topsoil and continually exposes subsoil that has lower C

  16. Restraint Stress Impairs Glucose Homeostasis Through Altered ...

    African Journals Online (AJOL)

    olayemitoyin

    condition that impairs the balance of the organism physiologically or .... period by a digital scale (Ohaus Scout Pro, Pine. Brook, New ..... White adipose tissue as endocrine organ and its role in obesity. Arch Med Res 2008; 39:715–28. Wang C, Mao X, Wang L, Liu M, Wetzel MD, Guan. KL, Dong LQ, Liu FJ. Adiponectin ...

  17. Evaluation of Resuspension from Propeller Wash in DoD Harbors

    Science.gov (United States)

    2016-09-01

    includes high-capacity lithium -ion batteries is also housed in the laser unit. The second unit is a camera unit with a CCD camera, a compact computer...V.J. Cabelli. 1992. Mapping of Benthic Enrichment Patterns in Narragansett Bay, RI. Estuaries 15:1–17. Wang, B., Q. Liao, H. Bootsma, and P. Wang

  18. Association of HS6ST3 gene polymorphisms with obesity and ...

    Indian Academy of Sciences (India)

    Supplementary data: Association of HS6ST3 gene polymorphisms with obesity and triglycerides: gene × gender interaction. Ke-Sheng Wang, Liang Wang, Xuefeng Liu and Min Zeng. J. Genet. 92, 395–402. Table 1. Associations of 117 SNPs with obesity in the Health ABC and Marshfield samples. Minor. OR Health.

  19. Study of the degree of deuteration on the microhardness of ...

    Indian Academy of Sciences (India)

    Author Affiliations. Baoan Liu1 Shaotao Sun2 Bo Wang1 Xun Sun1 Zhengping Wang1 Xinguang Xu1. State Key Laboratory of Crystal Materials, Shandong University, Jinan 250100, PR China; Administration Center, Shandong Academy of Information and Communication Technology, Jinan 250101, PR China ...

  20. Stabilizing Protein Effects on the Pressure Sensitivity of Fluorescent Gold Nanoclusters

    Science.gov (United States)

    2016-01-13

    Qi-Wei Li, Shui -Hong Li, Wei Ge, Xiao Chen, Hui Jiang, Xue-Mei Wang. Novel in situ biosynthesized fluorescent zinc nanoclusters for specific...synthesis and biological applications. Nano Today. 2011;6:401–418. 17. Wen F, Dong YH, Feng L, Wang S, Zhang SC, Zhang XR. Horseradish peroxidase

  1. Induction of a Pregnancy-Like Mammary Gland Differentiation by Docosapentaenoic Omega-3 Fatty Acid

    Science.gov (United States)

    2010-09-01

    are differentially affected by dietary remediation. Behav Brain Res 152:49-57. 17. Feng , L., Hatten, M.E. and Heintz, N. 1994. Brain lipid-binding...of ER- Yuenian Eric Shi,*† Yiding Chen,‡ Raduwan Dackour,* Louis Potters,* Shui Wang,† Qiang Ding,† Zhaoyi Wang,§ and Yiliang Ellie Liu* From the

  2. Extraction optimization and characterization of polysaccharide ...

    African Journals Online (AJOL)

    characterization and antioxidant activity of sulfated polysaccharide from the red seaweed Gracilaria birdiae. Food Hydrocolloid 2012; 27(27): 287-292. 22. Wang JL, Zhang J, Wang XF, Zhao BT, Wu YQ, Yao J. A comparison study on microwave-assisted extraction of. Artemisia sphaerocephala polysaccharides with.

  3. Evaluation of Resuspension from Propeller Wash in Pearl Harbor and San Diego Bay

    Science.gov (United States)

    2014-07-01

    Wang et al., 2000; 2004), sediment transport for Pearl Harbor, HI (Wang et al., 2009a; 2009b) and TMDL for fecal coliform and Combined Sewage...Sewer Overflows in the Port Washington Narrows and Fecal Coliform Transport in Sinclair and Dyes Inlets, Washington. Prepared by Space and Naval

  4. Three duplication events and variable molecular evolution ...

    Indian Academy of Sciences (India)

    Three duplication events and variable molecular evolution characteristics involved in multiple GGPS genes of six Solanaceae species. FENG LI CHUNYANG WEI CHAN QIAO ZHENXI CHEN PENG WANG PAN WEI RAN WANG LIFENG JIN JUN YANG FUCHENG LIN ZHAOPENG LUO. RESEARCH NOTE Volume 95 Issue ...

  5. Ice thickness, volume and subglacial topography of Urumqi Glacier ...

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Earth System Science; Volume 123; Issue 3. Ice thickness, volume and subglacial topography of Urumqi Glacier No. 1, Tianshan mountains, central Asia, by ground penetrating radar survey. Puyu Wang Zhongqin Li Shuang Jin Ping Zhou Hongbing Yao Wenbin Wang. Volume 123 Issue 3 April ...

  6. BH3-Amine and B(CH3)3-Amine Adducts as Additives for Liquid/Gel Hypergols and Solid Hybrid Rocket Motor Fuels: Property and Performance Predictions

    Science.gov (United States)

    2013-12-01

    Russian Journal of Inorganic Chemistry, 1995, 40, 811–816. Mathis, N. P.; Slocum -Wang, Z.; Felton, L. D.; Michaels, R. S. Development of a Reduced...Dichroism Spectra Using Density-Functional Force- Fields. Journal of Physical Chemistry, 1994, 98, 11623-11627. Stevenson, W. H.; Felton, L. D.; Slocum -Wang

  7. African Journal of Biotechnology - Vol 9, No 32 (2010)

    African Journals Online (AJOL)

    Optimization of fed-batch fermentation for a staphylokinase-hirudin fusion protein in Escherichia coli BL21 · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. G Zhang, G Zhong, X Wang, L Wang, Y Qin, A Yu, 5078-5083 ...

  8. South African Journal of Chemistry - Vol 61 (2008)

    African Journals Online (AJOL)

    Preparation, Structure Characterization and Thermal Decomposition Process of the Dysprosium(III) m-Methylbenzoate 1,10-Phenanthroline Complex · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. S-U Xu, J-J Zhang, N Ren, H-Y Zhang, R-F Wang, S-P Wang, 1-4 ...

  9. Remark on regularity criteria of a weak solution to the 3D MHD equations

    Directory of Open Access Journals (Sweden)

    Jae-Myoung Kim

    2017-04-01

    Full Text Available We study the regularity conditions for a weak solution to 3D MHD equations in a whole space $\\mathbb{R}^3$, based on the papers [C. He, Y. Wang, J. Differential Equations, 238(2007, No. 1, 1–17] and [W. Wang, J. Math. Anal. Appl., 328(2007, No. 2, 1082–1086].

  10. TaqMan Real-Time Polymerase Chain Reaction and ...

    African Journals Online (AJOL)

    TaqMan Real-Time Polymerase Chain Reaction and. Pyrosequencing using Single Nucleotide Polymorphism. Protocol for Rapid Determination of ALDH2 *2 in a Chinese. Population. Ju-yi Li1, Jin-hu Wu2, Yan Zhang2, Xiu-fang Wang2, Jie Jin2 and Yi Wang1*. 1Department of Pharmacy, The Central Hospital of Wuhan, ...

  11. Renius cornutus

    Science.gov (United States)

    Li, Wenjing; Huo, Lizhi; Ahrens, Dirk; Ren, Shunxiang; Wang, Xingmin

    2017-01-01

    A new monotypic genus of Chilocorini, Renius Li & Wang, gen. n. , with a new species R. cornutus Li et Wang, sp. n . is described from Tibet, China. All diagnostic features are illustrated. The relationships with other genera of Chilocorini are discussed and a key to Chinese genera of Chilocorini is provided.

  12. The Religion of Learning English in "English": A Language Educator's Reading

    Science.gov (United States)

    Gao, Xuesong

    2011-01-01

    This essay is my reading of "English," a novel based on author Wang Gang's experiences in Urumqi, Xinjiang Uyghur Autonomous Region, Northwest China during the Cultural Revolution (1966-1976). As a language educator, I was particularly interested in the way that Wang describes learning English in the novel. The essay focuses on three…

  13. Reference: 669 [Arabidopsis Phenome Database[Archive

    Lifescience Database Archive (English)

    Full Text Available psis. 21 3873-82 17933793 2007 Nov Development (Cambridge, England) Chen Jin-Gui|Chen Xiao-Ya|Ellis Brian E|Kwak Su-Hwan|Schiefelbein John|Wang Shucai|Zeng Qingning ... 669 http://metadb.riken.jp/db/SciNetS_ria224i/cria224u4ria224u17933793i Wang Shuca

  14. Mitochondrial DNA analysis reveals a low nucleotide diversity of ...

    African Journals Online (AJOL)

    Mitochondrial DNA analysis reveals a low nucleotide diversity of Caligula japonica in China. ... Mitochondrial DNA analysis reveals a low nucleotide diversity of Caligula japonica in China. Y Li, B Yang, H Wang, R Xia, L Wang, Z Zhang, L Qin, Y Liu ...

  15. Journal of Genetics | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    pp 171-178 Research Article. Cloning, characterization and promoter analysis of common carp hairy/Enhancer-of-split-related gene, her6 · Jing Liu Yong-Hua Sun Na Wang Ya-Ping Wang Zuo-Yan Zhu · More Details Abstract Fulltext PDF. Some members of hairy/Enhancer-of-split-related gene (HES) family have important ...

  16. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science. F Wang. Articles written in Bulletin of Materials Science. Volume 34 Issue 5 August 2011 pp 1033-1037. Synthesis of Mn-doped CeO2 nanorods and their application as humidity sensors · C H Hu C H Xia F Wang M Zhou P F Yin X Y Han · More Details Abstract Fulltext PDF.

  17. Forecasting Demand for KC-135 Sorties: Deploy to Dwell Impacts

    Science.gov (United States)

    2013-06-01

    of fields, ranging from tourism to utility prices. Wang used time series to model tourist arrivals in Hong Kong (Wang, 2004:367). Nogales et al... scripted events comprise part of operational planning, unforeseen events also play a major role. A regression model using operational considerations

  18. Synergistic Action of FOXP3 and TSC1 Pathways During Tumor Progression

    Science.gov (United States)

    2015-10-01

    precancerous lesions in prostate. Cancer Research, 2015 Apr 15;75(8):1714-24. PMID: 25712341. 3. Meredith LJ , Wang CM, Nascimento L, Liu R, Wang L...acute myeloid leukemia. Exp Hematol 34, 1480-1489. 53. Gomez-Curet, I., Perkins , R.S., Bennett, R., Feidler, K.L., Dunn, S.P., and Krueger, L.J. (2006). c

  19. A novel RNA-splicing mutation in TRAPPC2 gene causing X-linked ...

    Indian Academy of Sciences (India)

    Hong Guo1 Xueqing Xu1 Kai Wang1 Bo Zhang1 Guohong Deng2 Yan Wang1 Yun Bai1. Department of Medical Genetics, Third Military Medical University, Gaotanyan St, Chongqing 400038, People's Republic of China; Department of Infectious Diseases, Southwest Hospital, Third Military Medical University, Gaotanyan St, ...

  20. Journal Afrika Statistika ISSN 0852-0305 Distortion risk measures ...

    African Journals Online (AJOL)

    Key words: Coherence; Dependence structure; Distortion function; Risk measure; Risk theory; insurance; Wang ... distribution function (df) F. The DRM of rv X, due to Wang [17], is defined as follows: πψ[X] := ..... Let X1 and X2 be two risks with joint df represented by the Clayton copula Cθ,θ> 0 and Pareto-distributed margins.

  1. Bulletin of the Chemical Society of Ethiopia - Vol 21, No 2 (2007)

    African Journals Online (AJOL)

    GC/MS ANALYSIS OF COAL TAR COMPOSITION PRODUCED FROM COAL PYROLYSIS · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. Jianfang Jiang, Qiyu Wang, Yingyu Wang, Weicheng Tong, Bo Xiao, Bo Xiao, 229-240. http://dx.doi.org/10.4314/bcse.v21i2.

  2. HRD Learning Participation: An Empirical Study of E-Learning Completion

    Science.gov (United States)

    Wang, Greg G.; Foucar-Szocki, Diane; Griffin, Oris

    2006-01-01

    This study offers empirical evidence in HRD e-learning completion. Based on the Learning Participation Theory (LPT) (Wang & Wang, 2004), a study was conducted with U.S. corporate e-learners to explore the determinants of e-learning completion. The results generally confirmed the hypothesis by the LPT that individual, learning process, and…

  3. Bulletin of the Chemical Society of Ethiopia - Vol 22, No 2 (2008)

    African Journals Online (AJOL)

    Potentiometric titration curves of aluminium salt solutions and its species conversion in the hydrolysis-polymerization course · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. Chenyi Wang, Zhiping Han, Ping Wang, Nan Cui, Tingjun Lao, Peiqin Hong.

  4. Arsenic bioleaching in medical realgar ore and arsenic- bearing ...

    African Journals Online (AJOL)

    Wu XH, Sun DH, Zhuang ZX, Wang XR, Gong HF, Hong. JX, Lee FSC. Analysis and leaching characteristics of mercury and arsenic in Chinese medicinal material. Anal. Chim Acta 2002; 2: 311-323. 6. Ning N, Peng Z, Yuan L, Gou B, Zhang T, Wang K. Realgar nano-particles induce apoptosis and necrosis in leukemia cell ...

  5. 75 FR 12748 - Ocean Transportation Intermediary License Applicants

    Science.gov (United States)

    2010-03-17

    ..., Chairman. Qingfeng Wang dba Global Intertrans Logistics, 200 East Norwood Place, San Gabriel, CA 91776-3811, Officer: Qingfeng Wang, Sole Proprietor, (Qualifying Individual). TMO Global Logistics, LLC, 100 10th...: Vicente Memoli, Treasurer, (Qualifying Individual), Rafael Apitz, President. Lama Shipping & Logistics...

  6. Sadhana | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Sadhana. JINTING WANG. Articles written in Sadhana. Volume 41 Issue 8 August 2016 pp 817-823. A closed-form solution for a two-server heterogeneous retrial queue with threshold policy · TIEN VAN DO DENES PAPP RAM CHAKKA JINTING WANG JANOS SZTRIK · More Details Abstract Fulltext PDF.

  7. Targeting Dysregulated Epigenetic Enzymes for Prostate Cancer Treatment

    Science.gov (United States)

    2016-10-01

    decreased protein levels of SIRT2 leads to the inability to down-regulate the hyper -acetylated form of p300. SIRT2-dependent deacetylation of p300...nature06546. 32. Thompson PR, Wang D, Wang L, Fulco M, Pediconi N, Zhang D, et al. Regulation of the p300 HAT domain via a novel activation loop . Nat Struct

  8. Journal of Genetics | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Genetics. ANSI WANG. Articles written in Journal of Genetics. Volume 96 Issue 2 June 2017 pp 313-318 RESEARCHARTICLE. Molecular characterization and expression of the GDF9 gene in New Zealand white rabbits · CAIXIA SUN SHUYU XIE TAO HUANG WEI ZHANG ANSI WANG DAN ...

  9. Harnessing Solar Power: Novel Strategies for Rational Design of Photocatalysts and Photovoltaic Materials

    Science.gov (United States)

    2015-09-01

    Singh, M. Westberg, C. Wang, P. D. Dahlberg, T. Gellen , A. T. Gardiner, R. J. Cogdell and G. S. Engel , “Towards quantification of vibronic coupling in...Publications (published) during reporting period: V. P. Singh, M. Westberg, C. Wang, P. D. Dahlberg, T. Gellen , A. T. Gardiner, R. J. Cogdell and G. S

  10. Dimedone Derivative

    African Journals Online (AJOL)

    cyclohexane-1,3-dione} Plays an. Important Role in Breast Cancer Treatment. Ling-Qin Song1, Hua-Feng Kang1*, Di Liu1, Zhi-Jun Dai1, Jian-Jun He2, Bao-. Feng Wang1, Yang Zhao1, Xi-Jing Wang1 and Wen-Tao Xi1. 1Department of Oncology ...

  11. Arithmetical Fourier and Limit values of elliptic modular functions

    Indian Academy of Sciences (India)

    2

    Information: Corresponding Author's Institution: Institute of Applied Mathematics, Shangluo University. Corresponding Author's Secondary. Institution: First Author: Nianliang Wang, PH.D. First Author Secondary Information: Order of Authors: Nianliang Wang, PH.D .... whose right-hand side is the Fourier series. −. 1 π. ∞. ∑.

  12. Tropical Journal of Pharmaceutical Research - Vol 14, No 3 (2015)

    African Journals Online (AJOL)

    siRNAs Targeting Viral Protein 5: The Major Capsid Protein of Herpes Simplex Virus-1 Affects its Propagation and Cytoskeleton · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. K Ma, F Jin, Q Wang, Z Ren, K Zheng, Y Wang, 391-397.

  13. Physiological roles of plastid terminal oxidase in plant stress ...

    Indian Academy of Sciences (India)

    Besides, the use of PTOX inhibitor to H. pluvialis was shown to cause severe membrane lipid peroxidation with reduced astaxanthin content under stress conditions (Wang ... phosphate deprivation (Moseley et al. 2006; Li et al. 2008;. Wang et al. 2009). Furthermore, an analysis on the promoter of H. pluvialis PTOX gene ...

  14. 5,7-Dimethoxycoumarin inhibits neuronal apoptosis by targeting ...

    African Journals Online (AJOL)

    Stem Cells 2014; 32: 473‑486. 8. Yang B, Ye D, Wang Y. Caspase-3 as a therapeutic target for heart failure. Expert Opin Ther Targets 2013;. 17: 255‑263. 9. Zhang ZN, Li JY, Zhao Y, Wang JQ, Huang C, Fan GQ. Effects of Tongnao Huoluo acupuncture therapy on. Caspase-3 and Bcl‑2 of rats with acute cerebral infarction.

  15. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Effect of heat treatment on structure and magnetic properties of FeCoNi/CNTs nanocomposites · H Q Wu D M Xu Q Wang Y Z Yao Q Y Wang G Q Su · More Details Abstract Fulltext PDF. Fe46Co35Ni19/CNTs nanocomposites have been prepared by an easy two-step route including adsorption and heat treatment processes.

  16. Ocean Spectral Data Assimilation Without Background Error Covariance Matrix

    Science.gov (United States)

    2016-01-01

    533 Chu PC, Wang GH, Chen YC (2002) Japan/East Sea (JES) circulation and thermohaline 534 structure, Part 3, Autocorrelation Functions. J Phys...Oceanogr, 32, 3596-3615. 535 536 Chu PC, Wang GH (2003) Seasonal variability of thermohaline front in the central South China 537 Sea. J Oceanogr, 59

  17. Chinese People’s Liberation Army Missile Unit (Selected Articles)

    Science.gov (United States)

    1986-10-15

    Large Payload Rocket, Photographed by Liu Zibing............. 35 A March of Ten Thousand Miles, by Lo Genxing , Zhang Aiming, Wang Honde, Shuel Yianping...TEN THOUSAND MILES Lo Genxing , Zhang Aiming, Wang Hende, Shei Yianping, Zhong Yiliu, Li Yajuan and Guan Weixing. Testing 39 fir~ Testing Marching off

  18. Pan-genome analysis of Senegalese and Gambian strains of ...

    African Journals Online (AJOL)

    Mbaye

    2016-11-09

    Nov 9, 2016 ... agalactiae: implications for the microbial "pan-genome". Proc. Natl. Acad. Sci. U.S.A 102:13950-13955. Wang DB, Tian B, Zhang ZP, Deng JY, Cui ZQ, Yang RF, Wang XY,. Wei HP, Zhang XE (2012). Rapid detection of Bacillus anthracis spores using a super-paramagnetic lateral-flow immunological.

  19. Expression of miR-126 and its potential function in coronary artery ...

    African Journals Online (AJOL)

    Expression of miR-126 and its potential function in coronary artery disease. Xiaoyan Wang1, Yajun Lian2, Xin Wen3, Jing Guo2, Zhiping Wang2,. Sheng Jiang2, Yaodong Hu2. 1. Department of Ultrasound, Heping Hospital Affiliated to Changzhi Medical College, Changzhi, Shanxi, China. 2. Department of Cardiology ...

  20. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science. HUA WANG. Articles written in Bulletin of Materials Science. Volume 36 Issue 3 June 2013 pp 389-393. Effects of Bi doping on dielectric and ferroelectric properties of PLBZT ferroelectric thin films synthesized by sol–gel processing · Hua Wang Li Liu Ji-Wen Xu Chang-Lai Yuan ...

  1. Journal of Genetics | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    TAO HUANG. Articles written in Journal of Genetics. Volume 96 Issue 1 March 2017 pp 3-8 RESEARCH ARTICLE. Cloning and expression analysis of zygote arrest 1 ( Zar1 ) in New Zealand white rabbits · DAN WANG SHU-YU XIE WEI ZHANG CAI-XIA SUN TAO HUANG AN-SI WANG XUE-LEI HAN GUI-RONG SUN MING ...

  2. Preparation of CuS nanoparticles embedded in poly(vinyl alcohol ...

    Indian Academy of Sciences (India)

    WINTEC

    free chemical route (Gautam et al 2004), microemulsions route (Dong et al 2002), precursor decomposition route. (Ou et al 2005), solid-state reaction route (Ni et al 2003;. Wang et al 2006), sonochemical synthesis (Wang et al. 2002; Xu et al 2006), non-aqueous solution process. (Zhang et al 2006), pickering emulsion route ...

  3. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science. Mingzhi Wang. Articles written in Bulletin of Materials Science. Volume 33 Issue 4 August 2010 pp 401-406 Mechanical Properties. Preparation of Ti3AlC2 by mechanically activated sintering of 3Ti/Al/2C/0.2Sn · Baoyan Liang Mingzhi Wang Xin Han Qin Zhou Xin Li.

  4. African Journal of Biotechnology - Vol 10, No 34 (2011)

    African Journals Online (AJOL)

    Genetic polymorphisms of 17 Y-chromosome STRs in Han population from Henan province of China · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. H Wu, K Wang, L Zhang, X Zhang, L Wang, W Yang, 6362-6371 ...

  5. A New Copper (I) Complex Based on 4-amino-3, 5-bis (3-pyridyl)-1 ...

    Indian Academy of Sciences (India)

    A New Copper(I) Complex Based on 4-amino-3,5-bis(3-pyridyl)-1,2,4-triazole: Synthesis, Crystal Structure, Theoretical Study, Thermal Behavior and Luminescence. CHEN AI-HUA MENG SU-CI ZHOU KAI WANG CONG-CONG ZHAO WEI WANG AI-JIAN QIAN JUN. Regular Article Volume 129 Issue 2 February 2017 pp ...

  6. DNA regulatory motif selection based on support vector machine ...

    African Journals Online (AJOL)

    Administrator

    2011-10-19

    Oct 19, 2011 ... analysis of ChIP-seq data. BMC Bioinformatics, 10: p. 299. Wang C, Wang H, Luo J, Hu Y, Wei L, Duan M, He H (2009). Selenium deficiency impairs host innate immune response and induces susceptibility to Listeria monocytogenes infection. BMC Immunol. 10: p. 55. Zamdborg L, Ma P (2009). Discovery of ...

  7. Conflict Prevention and Confidence Building Measures in the South China Sea

    Science.gov (United States)

    2013-03-01

    Philippines, Malaysia and Brunei. China and Taiwan have the same claim according to the Qing dynasty chronicles in the 19th century and a nine-dashed...their claims, it means the whole South China Sea will be in China’s control. They do not wish any kind of colonization by China to affect their...lives. According to the above direct causes and root causes, this region has formed a consensus among most countries. The previous colonized experience

  8. Clinical investigation of CT-guided ozone-blowing and fumigation ...

    African Journals Online (AJOL)

    STORAGESEVER

    2010-05-31

    May 31, 2010 ... Clinical investigation of CT-guided ozone-blowing and fumigation therapy for the chronic refractory cutaneous sinus and ulcer. Meng-Qi Wei1, Jian-Shou Zhou1, Hai-Tao Liu2, Yuan Yuan1, Jun-Qing Xu1, Yong Yang1, Jin-. Song Zhang1, Yong Peng1* and Yi Huan1*. 1Department of Radiology, Xijing ...

  9. JPRS Report, China.

    Science.gov (United States)

    1990-05-17

    as "Big Feng" (standing 1.82 meters tall and having the stature of a basketball player, Feng is currently vice chairman of ACFLAC, chairman of the...Square in his wheelchair to comfort the fasting students. On one occasion, Ai Qing and Bing Xin [0393 1800] met at Tiananmen Square. With the hunger...governing (under two titles, one is for providing urine-collecting bags and the other for wheelchair pushing). Every time a meeting is con- vened

  10. Preparation of poly(β-L-malic acid)-based charge-conversional nanoconjugates for tumor-specific uptake and cellular delivery

    OpenAIRE

    Zhou Q; Yang T; Qiao Y; Guo S; Zhu L; Wu H.

    2015-01-01

    Qing Zhou,1,* Tiehong Yang,1,* Youbei Qiao,1 Songyan Guo,1 Lin Zhu,2 Hong Wu11Department of Pharmaceutical Analysis, School of Pharmacy, Fourth Military Medical University, Xi’an, People’s Republic of China; 2Department of Pharmaceutical Sciences, Irma Lerma Rangel College of Pharmacy, Texas A&M University Health Science Center, Kingsville, Texas, USA*These authors contributed equally to this workAbstract: In this study, a multifunctional poly(β-L-malic ac...

  11. Awaiting a Spark: How Three Chinese Territorial Disputes Could Jeopardize Peace in Asia

    Science.gov (United States)

    2013-12-01

    bemoaning the lack of agricultural worth of the region that they dubbed a “barren wasteland,” while other officials believed the region served as a...over its seeming lack of agricultural value and the region remained under Qing control not as a tributary, but as a “special administrative zone...resolution.”114 With this in mind, Mark J. Valencia concludes in his essay, “The East China Sea Dispute: Context, Claims, Issues, and Possible Solutions

  12. On Tea Bowl from Jianzhan to Tenmoku: Material Culture and Intangible Culture in Cultural Diffusion

    OpenAIRE

    Jianping Guan

    2014-01-01

    According to precise and scientific literature that recorded, Chinese tea culture has a documented history of more than 1700 years. During which period, Yuan Dynasty was considered a crucial turning-point with great changes. The current tea culture in China is an adoption and innovation of Ming and Qing dynasty, especially in the form of processing technology. For those elements inherited from Tang and Song dynasties, however, they were more directly adopted systematically by Japan. Ever sinc...

  13. Exploration and Evaluation of Nanometer Low-power Multi-core VLSI Computer Architectures

    Science.gov (United States)

    2015-03-01

    Steven Helmer, Andrea Lapiana, Giuseppe Lapiana, Rich Linderman, Tom Renz, John Rooks, Ross Thompson, Lisa Weyna, and Qing Wu. iii 1...a script-based language that most EDA-vendors support called Tool Command Language (Tcl). John Ousterhout invented Tcl while he was a faculty...Integrated Circuit Technology, 2006. ICSICT 󈧊. 8th International Conference on, 2006, pp. 1610-1613. [11] R. Chau, J. Brask, S. Datta, G. Dewey , M

  14. Uyghurs in Xinjiang: United or Divided Against the PRC?

    Science.gov (United States)

    2012-09-01

    Crossroads, 301. 59 Millward, Eurasian Crossroads, 4. 19 suffocating travelers caught without shelter with seasonal sandstorms.60 The Tarim Basin in...the west to east natural gas pipeline, connecting Lunnan in the Tarim Basin to Shanghai, and the rehabilitation of the Tarim River.73 Other...were not allowed to settle permanently in or bring their families to the Tarim Basin .78 Qing authorities did not allow or encouraged Chinese

  15. Spectrally-Temporally Adapted Spectrally Modulated Spectrally Encoded (SMSE) Waveform Design for Coexistent CR-Based SDR Applications

    Science.gov (United States)

    2010-03-01

    under utilized channel resources. This has fueled a flurry of activity to advance communication capability using Cognitive Radio (CR) and Software...metropolitan area networks Specific requirements Part 11: Wireless LAN Medium Access Control ( MAC ) and Physical Layer (PHY) Specifications, 2007. 33...Communications Magazine, 46(4), June 2008. ISSN 0163-6804. 46. Qing Zhao, Ananthram Swami Yunxia Chen, Lang Tong. “Decentralized cog- nitive MAC for

  16. Chinese books on Western calendrical calculations and Japanese calendrical calculators in Edo era

    Science.gov (United States)

    Kobayashi, Tatsuhiko

    2005-06-01

    From the end of Ming to the beginning of Qing China many Western scientific books were translated into Chinese by Jesuit missionaries with cooperation of Chinese intellectuals. The Tokugawa government began to permit the importation of them as an exception to the Shogunate's seclusion policy in 1720. In this paper the author discussed the acceptances of them, especially Chinese books on Western calendrical calculations by Japanese calendrical calculators in 18th-19th centuries.

  17. Browse Author Index

    African Journals Online (AJOL)

    Items 1 - 50 of 284 ... Lara-Riegos, Julio Cesar · Lasić, Dario · Lateefat, Y · Latha, LY · Latha, LY · Lau, MS · Laure, Kouitcheu Mabeku B · Laure B, KM · Laurido, Claudio · Laurido, Claudio · Lavekar, GS · Lawal, IO · Lawal, OA · Lazhar, WB · López-Villegas, EO · Lü, F · Lǚ, Zhong Qing · Leanya, M · León, Karla Isabel Lira-De

  18. Dynamics Days Arizonia 1993. A Workshop held at Tempe, Arizona on 5-9 January 1993

    Science.gov (United States)

    1993-01-09

    ideas of chaos: sensitive dependence on initial conditions, fractals, strange attractors, and the like. The afternoon program featured Dr. Yorke, who... Democritus University of Thrace, Greece), Finite complex dynamical systems dimensional behavior of penetrative convection 31. James Howard (Utah State Univ...CAMBRIDGE, MA 02139 E-mail: NEILG@MEDIA.MIT.EDU JIN-QING FANG PO BOX 275-27 IVAN GJAJA CHINA INST. OF ATOMIC ENERGY UNIVERSITY OF MARYLAND BEIJING, CHINA

  19. The Sino-Russian Strategic Partnership: Prospects and Implications

    Science.gov (United States)

    2003-06-01

    after a period of decline, was replaced by the Manchu dynasty-the Qing. The Manchus were foreigners, and they too proceeded to restore control over...had almost no experience in administering large urban areas and developing modern industry. Although Western businesses existed in China by the...railway network expansion, and even urban architecture that clashed with China’s urban landscape.20 17

  20. The Five Buddha Districts on the Yunnan-Burma Frontier: A Political System Attached to the State

    Directory of Open Access Journals (Sweden)

    Jianxiong Ma

    2013-09-01

    Full Text Available The Five Buddha Districts system prevailed from the 1790s to the 1880s on the frontier between Yunnan, in Southwest China, and the Burmese Kingdom, in the mountainous areas to the west of the Mekong River. Through more than a century of political mobilization, the Lahu communities in this area became an integrated and militarized society, and their culture was reconstructed in the historical context of ethnic conflicts, competition, and cooperation among the Wa, Dai, and Han Chinese settlers. The political elites of the Five Buddha Districts, however, were monks who had escaped the strict orthodoxy of the Qing government to become local chieftains, or rebels, depending on political changes in southern Yunnan. As a centralized polity, the Five Buddha Districts system was attached to the frontier politics of the Qing state before the coming of European colonial powers. The Qing state provided a sociopolitical space for local groups to develop their political ideals between various powerful Dai-Shan chieftains. The negotiation, competition, and cooperation between the Five Buddha leadership and the Qing, Dai chieftains, and neighboring political powers had been thoroughly integrated into the frontier politics of this interdependent society for more than two hundred years. As the history of the Yunnan-Burma frontier formation shows that no mountain space existed to allow the natives to escape from the state through their shifting agriculture, and anarchism was not practiced by the mountain people who were separated from the state, the author argues that a stateless region like James Scott’s “Zomia” did not historically exist in this region.

  1. Reconstructing Order: Post-War Reconstruction after the Taiping Civil War, 1864-1874

    OpenAIRE

    Heselton, Christopher Carlton

    2017-01-01

    In the aftermath of the tumultuous Taiping Civil War (1851-1864), Qing officials began imagining a reconstruction of Chinese post-war society through broad programs that resettled refugees, demobilized the army, and rebuilt temples, roads, and academies. This was an ambitious program and unprecedented in the annals of Chinese history, seeking to radically restore Chinese society through government intervention. At the center of their plans, was an administration, the Reconstruction Bureau, th...

  2. Elizabeth J. Perry, Challenging the Mandate of Heaven. Social Protest and State Power in China

    OpenAIRE

    Rocca, Jean-Louis

    2007-01-01

    This book is in reality a collection of articles and contributions that have been published previously and partially rewritten by the author. An introduction is intended to bring some coherence to the whole. The chapters address various facets of “social protest” (violence between peasant communities, anti-tax revolts, worker agitation) in different historical contexts (the end of the Qing dynasty, the republican era, the socialist period and post-Mao China). A complete panorama is thus offer...

  3. International Workshop on Finite Elements for Microwave Engineering (11th) - FEM2012 Student Support Grants

    Science.gov (United States)

    2015-05-22

    and Qing H. Liu*1 1 Department of Electrical and Computer Engineering, Duke University, Box 90291, Durham, NC 27708 2Departamento de Ciencias e...1 Department of Electrical and Computer Engineering, Duke University, Box 90291, Durham, NC 27708 2Departamento de Ciencias e Ingenieŕıa de la...latest methods can be applied. ∗The authors want to acknowledge the support of Ministerio de Educación y Ciencia of Spain under projects TEC2010-18175

  4. Taxonomic updates and descriptions of four new Lophopini planthopper species (Hemiptera, Fulgoroidea, Lophopidae from Yunnan province, South China

    Directory of Open Access Journals (Sweden)

    Menglin Wang

    2016-03-01

    Full Text Available Taxonomic updates and descriptions of four new species from Yunnan, China are provided: three new species in the genus Pitambara Distant, 1906: P. triremiprocta Wang & Soulier-Perkins, sp. nov., P. impudica Wang & Bourgoin, sp. nov., P. tricorne Wang & Wang, sp. nov., and one new species in the genus Serida Walker, 1857: Serida parenthesisflexuosa Wang & Soulier-Perkins, sp. nov. A new identification key to Pitambara species is provided, as well as to the species of the genus Lacusa Stål, 1862. Lacusa yunnanensis Chou & Huang, 1985 stat. rev. is not considered as a synonym of the species L. fuscofasciata (Stål, 1854 anymore and Lacusa orientalis (Liang, 2000 is transferred to the genus Acothrura Melichar, 1915 as Acothrura orientalis (Liang, 2000 comb. nov.

  5. A hybrid parallel architecture for electrostatic interactions in the simulation of dissipative particle dynamics

    Science.gov (United States)

    Yang, Sheng-Chun; Lu, Zhong-Yuan; Qian, Hu-Jun; Wang, Yong-Lei; Han, Jie-Ping

    2017-11-01

    , which approximately take up most of the total simulation time. Although the parallel method CU-ENUF (Yang et al., 2016) based on GPU has achieved a qualitative leap compared with previous methods in electrostatic interactions computation, the computation capability is limited to the throughput capacity of a single GPU for super-scale simulation system. Therefore, we should look for an effective method to handle the calculation of electrostatic interactions efficiently for a simulation system with super-scale size. Solution method: We constructed a hybrid parallel architecture, in which CPU and GPU are combined to accelerate the electrostatic computation effectively. Firstly, the simulation system is divided into many subtasks via domain-decomposition method. Then MPI (Message Passing Interface) is used to implement the CPU-parallel computation with each computer node corresponding to a particular subtask, and furthermore each subtask in one computer node will be executed in GPU in parallel efficiently. In this hybrid parallel method, the most critical technical problem is how to parallelize a CUNFFT (nonequispaced fast Fourier transform based on CUDA) in the parallel strategy, which is conquered effectively by deep-seated research of basic principles and some algorithm skills. Restrictions: The HP-ENUF is mainly oriented to super-scale system simulations, in which the performance superiority is shown adequately. However, for a small simulation system containing less than 106 particles, the mode of multiple computer nodes has no apparent efficiency advantage or even lower efficiency due to the serious network delay among computer nodes, than the mode of single computer node. References: (1) S.-C. Yang, H.-J. Qian, Z.-Y. Lu, Appl. Comput. Harmon. Anal. 2016, http://dx.doi.org/10.1016/j.acha.2016.04.009. (2) S.-C. Yang, Y.-L. Wang, G.-S. Jiao, H.-J. Qian, Z.-Y. Lu, J. Comput. Chem. 37 (2016) 378. (3) S.-C. Yang, Y.-L. Zhu, H.-J. Qian, Z.-Y. Lu, Appl. Chem. Res. Chin. Univ

  6. Kim Wŏn-haeng’s Intellectual Influences on Hong Tae-yong: The Case of Relations between

    Directory of Open Access Journals (Sweden)

    Login Lok-yin Law

    2015-08-01

    Full Text Available In the 18th century Chosŏn (1392-1910, some scholars, such as Hong Tae-yong (1731-1783 advocated that Chosŏn should learn the advantages of the Qing (1644-1912 society to reform the social structure and government of Chosŏn. The school of these advocates has been known as Pukhak by historians. The intellectual factors of the school of Pukhak’s formation and development have been overlooked by the academia of Chosŏn intellectual history. In fact, Pukhak was closely related to the idea of the school of Nakhak which believed that nature of things was equivalent to humans. Kim Wŏn-haeng, was one of the supporters of Nakhak and Hong Tae-yong was one of the students of Kim. Hong’s thought and writing exposed that his thought was profoundly influenced by Kim Wŏn-haeng. Hong was deemed to be the first prominent scholar of the Pukhak School during the 18th century Chosŏn. Hong and other scholars of Pukhak advocated learning the new knowledge from Qing China even though it was a barbarian society. Therefore, this paper will investigate the intellectual relationships between Hong Tae-yong and Kim Wŏn-haeng to reveal how intellectuals of Nakhak shaped the formation of Pukhak School and exposed the idea of learning from Qing China.

  7. Interlopers at the Fringes of Empire: The Procurators of the Propaganda Fide Papal Congregation in Canton and Macao, 1700-1823

    Directory of Open Access Journals (Sweden)

    Eugenio Menegon

    2017-12-01

    Full Text Available The office of the procurator of the papal Sacred Congregation for the Propagation of the Faith (Sacra Congregatio de Propaganda Fide offers a unique case study of noncommercial interloping in the long eighteenth century in the Pearl River Delta, and reveals the complexity and fluidity of life at the intersection of Asian and European maritime environments in that special human ecosystem. The oceanic infrastructure of the Age of Sail and the Sino-Western trade system in Canton sustained the Catholic missionary enterprise in Asia, and the professional figure of the procurator represented its economic and political linchpin. Procurators were agents connected with both European and Qing imperial formations, yet not directly at their service. They utilized existing maritime trade networks to their own advantage without being integral parts of those networks’ economic mechanisms. All the while, they subverted Qing prohibitions against Christianity. Using sources preserved in Rome, this article offers new insights into the global mechanisms of trade, communication, and religious exchange embodied by the procurators-interlopers and their networks, with significant implications for the history of the Sino-Western trade system, Qing policies toward the West and Christianity, and the history of Asian Catholic missions.

  8. New diagnostic and therapeutic approach to thyroid-associated orbitopathy based on applied kinesiology and homeopathic therapy.

    Science.gov (United States)

    Moncayo, Roy; Moncayo, Helga; Ulmer, Hanno; Kainz, Hartmann

    2004-08-01

    To investigate pathogenetic mechanisms related to the lacrimal and lymphatic glands in patients with thyroid-associated orbitopathy (TAO), and the potential of applied kinesiology diagnosis and homeopathic therapeutic measures. Prospective. Thyroid outpatient unit and a specialized center for complementary medicine (WOMED, Innsbruck; R.M. and H.M.). Thirty-two (32) patients with TAO, 23 with a long-standing disease, and 9 showing discrete initial changes. All patients were euthyroid at the time of the investigation. Clinical investigation was done, using applied kinesiology methods. Departing from normal reacting muscles, both target organs as well as therapeutic measures were tested. Affected organs will produce a therapy localization (TL) that turns a normal muscle tone weak. Using the same approach, specific counteracting therapies (i.e., tonsillitis nosode and lymph mobilizing agents) were tested. Change of lid swelling, of ocular movement discomfort, ocular lock, tonsil reactivity and Traditional Chinese Medicine criteria including tenderness of San Yin Jiao (SP6) and tongue diagnosis were recorded in a graded fashion. Positive TL reactions were found in the submandibular tonsillar structures, the pharyngeal tonsils, the San Yin Jiao point, the lacrimal gland, and with the functional ocular lock test. Both Lymphdiaral (Pascoe, Giessen, Germany) and the homeopathic preparation chronic tonsillitis nosode at a C3 potency (Spagyra, Grödig, Austria) counteracted these changes. Both agents were used therapeutically over 3-6 months, after which all relevant parameters showed improvement. Our study demonstrates the involvement of lymphatic structures and flow in the pathogenesis of TAO. The tenderness of the San Yin Jiao point correlates to the above mentioned changes and should be included in the clinical evaluation of these patients.

  9. PREFACE: Preface

    Science.gov (United States)

    Luo, Qingming; Wang, Lihong V.; Tuchin, Valery V.

    2011-02-01

    )Ruey-Jen Sung, Stanford University (USA)A Dean Sherry, The University of Texas at Dallas (USA)Bruce Tromberg, University of California/Irvine (USA)Fujia Yang, Nottingham University (UK)Jianquan Yao, Tianjin University (China)Yixin Zeng, Sun Yat-sen University Cancer Center (China)Baoyong Zheng, Hua Wei Technologies Corporation, Inc (China) Program CommitteeWei R Chen, University of Central Oklahoma (USA)Zhongping Chen, University of California/Irvine (USA)Arthur Chiou, National Yang-Ming University (Taiwan, China)Frank Y S Chuang, University of California, Davis (USA)Zhihua Ding, Zhejiang University (China)Congwu Du, Brookhaven National Laboratory (USA)Stefan Haacke, Strasbourg University - IPCMS-DON (France)Weiping Han, Agency for Science, Technology and Research (A*STAR) (Singapore)Zheng Huang, University of Colorado Health Sciences Center (USA)Zhiwei Huang, National University of Singapore (Singapore)Steven L Jacques, Oregon Health & Science University (USA)Fu-Jen Kao, National Yang-Ming University (Taiwan, China)Hideaki Koizumi, Hitachi, Ltd (Japan)Xingde Li, Johns Hopkins University (USA)Yong-qing Li, East Carolina University (USA)Chengyi Liu, South China Normal University (China)Hong Liu, University of Oklahoma (USA)Zuhong Lu, Southeast University (China)Dennis L Matthews, University of California/Davis (USA)Avraham Mayevsky, Bar Ilan University (Israel)Stephen P Morgan, University of Nottingham (UK)Shoko Nioka, University of Pennsylvania (USA)Yingtian Pan, State University of New York at Stony Brook (USA)Alexander V Priezzhev, MV Lomonosov Moscow State University (Russia)Jianan Y Qu, The Hongkong University of Science and Technology (Hong Kong, China)Colin J R Sheppard, National University of Singapore (Singapore)Mamoru Tamura, Tsinghua University (China)Sergey Ulyanov, Saratov State University (Russia)Ruikang K Wang, Oregon Health & Science University (USA)Xunbin Wei, Fudan University (China)Da Xing, South China Normal University (China)Haishan Zeng, BC Cancer Research

  10. Numerical simulation of multi-phase phenomena in IVR related processes

    Energy Technology Data Exchange (ETDEWEB)

    Cheng, Xu [Karlsruher Institut fuer Technologie (KIT), Karlsruhe (Germany). Bereich Innovative Reaktorsysteme; Shanghai Jiao Tong Univ. (China). School of Nuclear Science and Engineering

    2016-05-15

    IVR (in-vessel retention) is one of the severe accident mitigation measures, which is widely applied in the advanced light water reactors (LWRs) such as KERENA of AREVA, AP1000 of Westinghouse and CAP1400 of SNPTC, and attracts extensive interests of the German and Chinese nuclear scientists. The ultimate target of IVR is to keep the core melt inside the reactor pressure vessel (RPV) and to provide cooling capability via water flowing outside the RPV, the so called external reactor vessel cooling (ERVC). This paper summarizes some activities ongoing in both KIT and SJTU (Shanghai Jiao Tong University) with a few results examples.

  11. Herbal Weight Loss Pill Overdose: Sibutramine Hidden in Pepper Pill

    OpenAIRE

    Pamukcu Gunaydin, Gul; Dogan, Nurettin Ozgur; Levent, Sevcan; Kurtoglu Celik, Gulhan

    2015-01-01

    Supposedly herbal weight loss pills are sold online and are widely used in the world. Some of these products are found to contain sibutramine by FDA and their sale is prohibited. We report a case of a female patient who presented to the emergency department after taking slimming pills. 17-year-old female patient presented to the emergency room with palpitations, dizziness, anxiety, and insomnia. She stated that she had taken 3 pills named La Jiao Shou Shen for slimming purposes during the day...

  12. Mechanisms Related to Different Generations of gamma’ Precipitation During Continuous Cooling of a Nickel Base Superalloy

    Science.gov (United States)

    2012-04-01

    samples were prepared by a dual-beam FIB instrument (FEI Nova Nanolab 200) system using a Ga ion beam. The ion beam thinning was carried out in multiple...JP, Wang Y, Mills MJ. Scripta Mater 2007;57:767. [10] Wen YH, Simmons JP, Shen C, Woodword C, Wang Y. Acta Mater 2003;51:1123. [11] Wen YH, Wang B...Viswanathan GB, Banerjee R, Singh A, Nag S, Tiley J, Fraser HL. Scripta Mater 2011;65:485. distribution unlimited.

  13. Comment on the level-set method used in ‘Numerical study on mobilization of oil slugs in capillary model with level set approach’

    Directory of Open Access Journals (Sweden)

    Åsmund Ervik

    2016-01-01

    Full Text Available This is a comment on a 2014 paper by Dai and Wang. It is argued that the validation in Dai and Wang's paper is an artifact caused by the boundary conditions of the level-set function, meaning that the effects reported in their paper have little physical relevance. Simulations are presented using Dai and Wang's methods to illustrate this claim. Remarks are made on the choice of boundary conditions for the level-set function, as well as the frequency of reinitialization, both of which are important topics that are sometimes overlooked. A simple criterion is proposed for determining the appropriate reinitialization frequency in simulations of highly viscous flows.

  14. The Duality of Fracture Behavior in a Ca-Based Bulk-Metallic Glass (Postprint)

    Science.gov (United States)

    2011-06-01

    Structural Materials Division ______________________________________ ROBERT T. MARSHALL, Deputy Chief Structural Materials...G.Y. Wang, P.K.. Liaw, O.N. Senkov, and D.B. Miracle: Metall. Mater. Trans. A, 2010, vol. 41A, pp. 1775 79. 17. J.J. Lewandowski and A.L. Greer: Nat...X.K. Xi, D.Q. Zhao, M.X. Pan, W.H. Wang, Y. Wu, and J.J. Lewandowski : Phys. Rev. Lett., 2005, vol. 94, pp. 125510 4. 28. J.J. Lewandowski , W.H. Wang

  15. The Effect of a Winglet on the Spatial Vortex of a Slender Body at High Angle of Attack,

    Science.gov (United States)

    1986-07-07

    OF A SLENDER BODY AT HIGH 0)ANGLE OF ATTACK !,D) toF by ~Wang Zixing, Wu Genxing Approved for public release;L"’J Distribution unlimited. q Ui...ATTACK By: Wang Zixing, Wu Genxing English pages: 12 Source: Konggi Donglixue Xuebao, Vol. 3, Nr. 1, 1985, pp. 49-53 Country of origin: China Translated by...U ~ ~ ’~ IL--c-k. au -ILI . W THE EFFECT OF A WINGLET ON THE SPATIAL VORTEX OF A SLENDER BODY AT HIGH ANGLE OF ATTACK Wang Zixing Wu Genxing

  16. Genome-wide analyses of SWEET family proteins reveal involvement in fruit development and abiotic/biotic stress responses in banana.

    Science.gov (United States)

    Miao, Hongxia; Sun, Peiguang; Liu, Qing; Miao, Yulu; Liu, Juhua; Zhang, Kaixing; Hu, Wei; Zhang, Jianbin; Wang, Jingyi; Wang, Zhuo; Jia, Caihong; Xu, Biyu; Jin, Zhiqiang

    2017-06-14

    Sugars Will Eventually be Exported Transporters (SWEET) are a novel type of sugar transporter that plays crucial roles in multiple biological processes. From banana, for the first time, 25 SWEET genes which could be classified into four subfamilies were identified. Majority of MaSWEETs in each subfamily shared similar gene structures and conserved motifs. Comprehensive transcriptomic analysis of two banana genotypes revealed differential expression patterns of MaSWEETs in different tissues, at various stages of fruit development and ripening, and in response to abiotic and biotic stresses. More than 80% MaSWEETs were highly expressed in BaXi Jiao (BX, Musa acuminata AAA group, cv. Cavendish), in sharp contrast to Fen Jiao (FJ, M. acuminata AAB group) when pseudostem was first emerged. However, MaSWEETs in FJ showed elevated expression under cold, drought, salt, and fungal disease stresses, but not in BX. Interaction networks and co-expression assays further revealed that MaSWEET-mediated networks participate in fruit development signaling and abiotic/biotic stresses, which was strongly activated during early stage of fruit development in BX. This study provides new insights into the complex transcriptional regulation of SWEETs, as well as numerous candidate genes that promote early sugar transport to improve fruit quality and enhance stress resistance in banana.

  17. Multiple imputation was a valid approach to estimate absolute risk from a prediction model based on case-cohort data.

    Science.gov (United States)

    Mühlenbruch, Kristin; Kuxhaus, Olga; di Giuseppe, Romina; Boeing, Heiner; Weikert, Cornelia; Schulze, Matthias B

    2017-04-01

    To compare weighting methods for Cox regression and multiple imputation (MI) in a case-cohort study in the context of risk prediction modeling. Based on the European Prospective Investigation into Cancer and Nutrition Potsdam study, we estimated risk scores to predict incident type-2 diabetes using full cohort data and case-cohort data assuming missing information on waist circumference outside the case-cohort (∼90%). Varying weighting approaches and MI were compared with regard to the calculation of relative risks, absolute risks, and predictive abilities including C-index, the net reclassification improvement, and calibration. The full cohort comprised 21,845 participants, and the case-cohort comprised 2,703 participants. Relative risks were similar across all methods and compatible with full cohort estimates. Absolute risk estimates showed stronger disagreement mainly for Prentice and Self & Prentice weighting. Barlow and Langholz & Jiao weighting methods and MI were in good agreement with full cohort analysis. Predictive abilities were closest to full cohort estimates for MI or for Barlow and Langholz & Jiao weighting. MI seems to be a valid method for deriving or extending a risk prediction model from case-cohort data and might be superior for absolute risk calculation when compared to weighted approaches. Copyright © 2017 The Author(s). Published by Elsevier Inc. All rights reserved.

  18. Effect of Lixujieyu recipe in combination with Five Elements music therapy on chronic fatigue syndrome.

    Science.gov (United States)

    Zhang, Zhenxian; Cai, Zhixing; Yu, Yonghui; Wu, Lili; Zhang, Ye

    2015-12-01

    To observe the clinical effects of the Lixujieyu recipe combined with Five Elements music therapy on chronic fatigue syndrome (CFS) identified as the symptom patterns of liver stagnation and spleen deficiency in terms of Traditional Chinese Medicine. Patients with CFS were randomly divided into treatment group 1 (Lixujieyu recipe combined with Gong-Tune, n = 15); treatment group 2 (Lixujieyu recipe combined with Jiao-Tune, n = 15); treatment group 3 (Lixujieyu recipe combined with Yu-Tune, n = 15); treatment group 4 (Lixujieyu recipe combined with Shang-Tune, n = 15); treatment group 5 (Lixuiievu recipe combined with Zhi-Tune, n = 15); and the control group (Lixujieyu recipe alone, n = 15). Chinese medicine was given twice daily, and music was listened to for 45 minutes daily, 5 days a week. All patients were treated for 4 weeks. Patients were assessed via the Fatigue Scale, the Hamilton Depression Rating Scale, and the Hamilton Anxiety Rating Scale before and after treatment. Treatment groups 1 and 2 had better effects on relieving the symptoms of physical fatigue related to anxiety and depression than the control group (P < 0.05). Lixujieyu recipe combined with Gong-Tune or Jiao-Tune significantly relieved the symptoms of CFS.

  19. Dissolving and biodegradable microneedle technologies for transdermal sustained delivery of drug and vaccine

    Directory of Open Access Journals (Sweden)

    Hong X

    2013-09-01

    Full Text Available Xiaoyun Hong,1,2,* Liangming Wei,3,* Fei Wu,2,* Zaozhan Wu,2 Lizhu Chen,2 Zhenguo Liu,1 Weien Yuan2 1Department of Neurology, Xinhua Hospital, Shanghai, People's Republic of China; 2School of Pharmacy, Shanghai JiaoTong University, Shanghai, People's Republic of China; 3Research Institute of Micro/Nano Science and Technology, Shanghai JiaoTong University, Shanghai, People's Republic of China *These authors contributed equally to this work Abstract: Microneedles were first conceptualized for drug delivery many decades ago, overcoming the shortages and preserving the advantages of hypodermic needle and conventional transdermal drug-delivery systems to some extent. Dissolving and biodegradable microneedle technologies have been used for transdermal sustained deliveries of different drugs and vaccines. This review describes microneedle geometry and the representative dissolving and biodegradable microneedle delivery methods via the skin, followed by the fabricating methods. Finally, this review puts forward some perspectives that require further investigation. Keywords: microneedle, dissolving, biodegradable, sustained release

  20. An Analytical Solution for Predicting the Vibration-Fatigue-Life in Bimodal Random Processes

    Directory of Open Access Journals (Sweden)

    Chaoshuai Han

    2017-01-01

    Full Text Available Predicting the vibration-fatigue-life of engineering structures subjected to random loading is a critical issue for. Frequency methods are generally adopted to deal with this problem. This paper focuses on bimodal spectra methods, including Jiao-Moan method, Fu-Cebon method, and Modified Fu-Cebon method. It has been proven that these three methods can give acceptable fatigue damage results. However, these three bimodal methods do not have analytical solutions. Jiao-Moan method uses an approximate solution, Fu-Cebon method, and Modified Fu-Cebon method needed to be calculated by numerical integration which is obviously not convenient in engineering application. Thus, an analytical solution for predicting the vibration-fatigue-life in bimodal spectra is developed. The accuracy of the analytical solution is compared with numerical integration. The results show that a very good agreement between an analytical solution and numerical integration can be obtained. Finally, case study in offshore structures is conducted and a bandwidth correction factor is computed through using the proposed analytical solution.