WorldWideScience

Sample records for w71 type 5-2

  1. 75 FR 43564 - TA-W-71,483, Continental Airlines, Inc., Reservations Division, Houston, TX; TA-W-71,483A...

    Science.gov (United States)

    2010-07-26

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF LABOR Employment and Training Administration TA-W-71,483, Continental Airlines, Inc., Reservations Division, Houston, TX; TA-W-71,483A, Continental Airlines, Inc., Reservations Division, Tampa, FL; TA-W-71,483B...

  2. 75 FR 66794 - Notice of Affirmative Determination Regarding Application for Reconsideration: TA-W-71,572...

    Science.gov (United States)

    2010-10-29

    ... Reconsideration: TA-W-71,572, Severstal Wheeling, Inc., a Subsidiary of Severstal North America, Inc., Martins Ferry, OH; TA-W-71,572A, Severstal Wheeling, Inc., a Subsidiary of Severstal North America, Inc., Yorkville, OH; TA-W-71,572B, Severstal Wheeling, Inc., a Subsidiary of Severstal North America, Inc., Mingo...

  3. A human osteosarcoma cell line expressing herpes simplex type-1 thymidine kinase: studies with radiolabeled (E)-5-(2-iodovinyl)-2'-fluoro-2'-deoxyuridine

    Energy Technology Data Exchange (ETDEWEB)

    Morin, Kevin W. [Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, T6G 2N8 (Canada); Duan Weili [Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, T6G 2N8 (Canada); Knaus, Edward E. [Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, T6G 2N8 (Canada); McEwan, Alexander J.B. [Department of Radiology and Diagnostic Imaging, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, T6G 2N8 (Canada); Wiebe, Leonard I. [Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, T6G 2N8 (Canada)]. E-mail: leonard.wiebe@ualberta.ca

    2005-07-01

    Introduction: (E)-5-(2-Iodovinyl)-2'-fluoro-2'-deoxyuridine (IVFRU) is a pyrimidine nucleoside analogue that accumulates selectively in murine cells expressing herpes simplex type-1 thymidine kinase (HSV-1 TK). The uptake of [{sup 125}I]IVFRU in human 143B osteosarcoma cells transduced with a retroviral vector bearing the HSV-1 TK gene (143B-LTK cells) is now reported. Methods: HSV-1 TK gene expression in 143B-LTK cells was confirmed by Western blotting and reverse transcriptase (RT)-PCR. Cell and subcellular uptake of [{sup 125}I]IVFRU was determined in cell culture, and whole body biodistribution after intravenous injection of [{sup 125}I]IVFRU was determined using nude mice bearing implanted 143B or 143B-LTK tumors. Results: Although IVFRU was less toxic to the human cell line expressing HSV-1 TK (143B-LTK) than ganciclovir, both IVFRU and ganciclovir were not toxic to the cell line not expressing HSV-1 TK (143B). When cells were exposed to [{sup 125}I]IVFRU in vitro, only the 143B-LTK cells accumulated radioactivity. The acid-soluble fraction from 143B-LTK cell lysates contained 8-fold greater activity than the acid-insoluble fraction after an 8-h exposure to [{sup 125}I]IVFRU. Biodistribution of [{sup 125}I]IVFRU in nude mice bearing subcutaneous 143B and 143B-LTK tumors revealed widespread distribution of the nucleoside in vivo but with specific localization in 143B-LTK tumors. Conclusion: The underlying biochemical process of metabolic entrapment of IVFRU in human osteosarcoma cells expressing HSV-1 TK is responsible for selective localization in these cells. The differences in subcellular distribution into the nucleic acid fraction, and in cytotoxicity, reflect the importance of cell type and lineage as determinants of the performance of gene imaging radiopharmaceuticals.

  4. Imaging of Herpes Simplex Virus Type 1 Thymidine Kinase Gene Expression with Radiolabeled 5-(2-iodovinyl)-2'-deoxyuridine (IVDU) in Liver by Hydrodynamic-based Procedure

    Energy Technology Data Exchange (ETDEWEB)

    Song, In Ho; Lee, Tae Sup; Kang, Joo Hyun; Lee, Yong Jin; Kim, Kwang Il; An, Gwang Il; Chung, Wee Sup; Cheon, Gi Jeong; Choi, Chang Woon; Lim, Sang Moo [Korea Institute of Radiological and Medical Sciences, Seoul (Korea, Republic of)

    2009-10-15

    Hydrodynamic-based procedure is a simple and effective gene delivery method to lead a high gene expression in liver tissue. Non-invasive imaging reporter gene system has been used widely with herpes simplex virus type 1 thymidine kinase (HSV1-tk) and its various substrates. In the present study, we investigated to image the expression of HSV1-tk gene with 5-(2-iodovinyl)-2'-deoxyuridine (IVDU) in mouse liver by the hydrodynamicbased procedure. HSV1-tk or enhanced green fluorescence protein (EGFP) encoded plasmid DNA was transferred into the mouse liver by hydrodynamic injection. At 24 h post-injection, RT-PCR, biodistribution, fluorescence imaging, nuclear imaging and digital wholebody autoradiography (DWBA) were performed to confirm transferred gene expression. In RT-PCR assay using mRNA from the mouse liver, specific bands of HSV1-tk and EGFP gene were observed in HSV1-tk and EGFP expressing plasmid injected mouse, respectively. Higher uptake of radiolabeled IVDU was exhibited in liver of HSV1-tk gene transferred mouse by biodistribution study. In fluorescence imaging, the liver showed specific fluorescence signal in EGFP gene transferred mouse. Gamma-camera image and DWBA results showed that radiolabeled IVDU was accumulated in the liver of HSV1-tk gene transferred mouse. In this study, hydrodynamic-based procedure was effective in liver-specific gene delivery and it could be quantified with molecular imaging methods. Therefore, co-expression of HSV1-tk reporter gene and target gene by hydrodynamic-based procedure is expected to be a useful method for the evaluation of the target gene expression level with radiolabeled IVDU.

  5. 10 CFR 960.5-2-3 - Meteorology.

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 4 2010-01-01 2010-01-01 false Meteorology. 960.5-2-3 Section 960.5-2-3 Energy DEPARTMENT OF ENERGY GENERAL GUIDELINES FOR THE PRELIMINARY SCREENING OF POTENTIAL SITES FOR A NUCLEAR WASTE REPOSITORY Preclosure Guidelines Preclosure Radiological Safety § 960.5-2-3 Meteorology. (a) Qualifying...

  6. 10 CFR 960.5-2-8 - Surface characteristics.

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 4 2010-01-01 2010-01-01 false Surface characteristics. 960.5-2-8 Section 960.5-2-8... Closure § 960.5-2-8 Surface characteristics. (a) Qualifying condition. The site shall be located such that, considering the surface characteristics and conditions of the site and surrounding area, including surface...

  7. 10 CFR 960.5-2-5 - Environmental quality.

    Science.gov (United States)

    2010-01-01

    ... environmental factors. (c) Potentially adverse conditions. (1) Projected major conflict with applicable Federal... 10 Energy 4 2010-01-01 2010-01-01 false Environmental quality. 960.5-2-5 Section 960.5-2-5 Energy... REPOSITORY Preclosure Guidelines Environment, Socioeconomics, and Transportation § 960.5-2-5 Environmental...

  8. 5 CFR 5.2 - Investigation and evaluations.

    Science.gov (United States)

    2010-01-01

    ... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false Investigation and evaluations. 5.2 Section 5.2 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE RULES REGULATIONS, INVESTIGATION, AND ENFORCEMENT (RULE V) § 5.2 Investigation and evaluations. The Director may secure effective...

  9. 10 CFR 960.5-2-10 - Hydrology.

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 4 2010-01-01 2010-01-01 false Hydrology. 960.5-2-10 Section 960.5-2-10 Energy DEPARTMENT OF ENERGY GENERAL GUIDELINES FOR THE PRELIMINARY SCREENING OF POTENTIAL SITES FOR A NUCLEAR WASTE... Hydrology. (a) Qualifying condition. The site shall be located such that the geohydrologic setting of the...

  10. 40 CFR 204.5-2 - National security exemptions.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 24 2010-07-01 2010-07-01 false National security exemptions. 204.5-2... PROGRAMS NOISE EMISSION STANDARDS FOR CONSTRUCTION EQUIPMENT General Provisions § 204.5-2 National security... for a national security exemption is required. (c) For purposes of section 11(d) of the Act, any...

  11. 40 CFR 205.5-2 - National security exemptions.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 24 2010-07-01 2010-07-01 false National security exemptions. 205.5-2... PROGRAMS TRANSPORTATION EQUIPMENT NOISE EMISSION CONTROLS General Provisions § 205.5-2 National security... a national security exemption is required. (c) For purposes of section 11(d) of the Act, any...

  12. 10 CFR 960.5-2-9 - Rock characteristics.

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 4 2010-01-01 2010-01-01 false Rock characteristics. 960.5-2-9 Section 960.5-2-9 Energy... Rock characteristics. (a) Qualifying condition. The site shall be located such that (1) the thickness and lateral extent and the characteristics and composition of the host rock will be suitable for...

  13. The quantum Hall effect at 5/2 filling factor.

    Science.gov (United States)

    Willett, R L

    2013-07-01

    Experimental discovery of a quantized Hall state at 5/2 filling factor presented an enigmatic finding in an established field of study that has remained an open issue for more than twenty years. In this review we first examine the experimental requirements for observing this state and outline the initial theoretical implications and predictions. We will then follow the chronology of experimental studies over the years and present the theoretical developments as they pertain to experiments, directed at sets of issues. These topics will include theoretical and experimental examination of the spin properties at 5/2; is the state spin polarized? What properties of the higher Landau levels promote development of the 5/2 state, what other correlation effects are observed there, and what are their interactions with the 5/2 state? The 5/2 state is not a robust example of the fractional quantum Hall effect: what experimental and material developments have allowed enhancement of the effect? Theoretical developments from initial pictures have promoted the possibility that 5/2 excitations are exceptional; do they obey non-abelian statistics? The proposed experiments to determine this and their executions in various forms will be presented: this is the heart of this review. Experimental examination of the 5/2 excitations through interference measurements will be reviewed in some detail, focusing on recent results that demonstrate consistency with the picture of non-abelian charges. The implications of this in the more general physics picture is that the 5/2 excitations, shown to be non-abelian, should exhibit the properties of Majorana operators. This will be the topic of the last review section.

  14. Hyperon resonances with spin-5/2 in kaon photoproduction

    Science.gov (United States)

    Nurussalam, A. I.; Mart, T.

    2017-07-01

    The effects of spin-5/2 hyperon resonances have been investigated in the photoproduction of kaon γp → K+Λ. To this end, we used the previously constructed isobar model and included a number of hyperon resonances in the u-channel of the background terms to investigated the effect of spin-5/2 hyperon resonances. To construct the vertex we followed the prescription of Pascalutsa, whereas to model the high-spin propagator we have adopted the recipe of Vrancx. We regularized the u-channel in order to avoid the singularity, since numerically the value of Mandelstam variable u could be zero. By minimizing the value of χ2 we have improved the consistency of the model to the experimental data, especially in the case of the cross-section and polarization observables. We have found that the spin-5/2 hyperon resonances contribute significantly to the kaon photoproduction process, especially in the backward directions.

  15. 36 CFR 5.2 - Alcoholic beverages; sale of intoxicants.

    Science.gov (United States)

    2010-07-01

    ... 36 Parks, Forests, and Public Property 1 2010-07-01 2010-07-01 false Alcoholic beverages; sale of... INTERIOR COMMERCIAL AND PRIVATE OPERATIONS § 5.2 Alcoholic beverages; sale of intoxicants. (a) The sale of alcoholic, spirituous, vinous, or fermented liquor, containing more than 1 percent of alcohol by weight...

  16. The Mars Climate Database (MCD version 5.2)

    Science.gov (United States)

    Millour, E.; Forget, F.; Spiga, A.; Navarro, T.; Madeleine, J.-B.; Montabone, L.; Pottier, A.; Lefevre, F.; Montmessin, F.; Chaufray, J.-Y.; Lopez-Valverde, M. A.; Gonzalez-Galindo, F.; Lewis, S. R.; Read, P. L.; Huot, J.-P.; Desjean, M.-C.; MCD/GCM development Team

    2015-10-01

    The Mars Climate Database (MCD) is a database of meteorological fields derived from General Circulation Model (GCM) numerical simulations of the Martian atmosphere and validated using available observational data. The MCD includes complementary post-processing schemes such as high spatial resolution interpolation of environmental data and means of reconstructing the variability thereof. We have just completed (March 2015) the generation of a new version of the MCD, MCD version 5.2

  17. Progress report on first year of WP5.2. Including detailed description of planned research for WP 5.2

    Energy Technology Data Exchange (ETDEWEB)

    Ellemers, N.; Van Dijk, E.; Terwel, B.; De Vries, G. [Leiden University, Leiden (Netherlands)

    2010-10-15

    This document contains the progress report on the first half year of the CATO-2 WP5.2 PhD project 'Framing effects in communication about CCS'. In the first few months a literature study has been conducted, both on (factors that influence) public perceptions and acceptance of CCS, and on framing. In the last two month, a first study was designed. This study consists of an experiment designed to examine how framing a company's involvement in CCS in terms of economic benefits and/or CSR of the organization affects the corporate image, trust, and perceived 'greenwashing' (deceit). Furthermore, this experiment serves to test the quality of newly developed questionnaires to measure these variables. In addition, this document contains a detailed description of the research planned for WP5.2 written by senior (CATO-2) researchers from January 2010 on. The objective of the research planned for WP5.2 is to examine whether framing of communications by an organization can improve the perceived credibility and trustworthiness of the organization and the information provided. This issue will be examined by a combination of experimental studies and a survey-type study.

  18. Tribological resistance of high speed steel HS 6-5-2 remelted with electric arc

    Directory of Open Access Journals (Sweden)

    A. Dziedzic

    2009-07-01

    Full Text Available The intensity of tribological wear of the high speed steel HS 6-5-2 remelted with the GTAW method has been compared to the heat treatment steel in a conventional way. Moreover, the types of the wear appeared during the friction. The tribiological research, were done in the technically dry friction conditions on a testing machine of the pin-on-disc T-01M. The smallest intensity of wear was shown by the high speed steel remelted with the parameters leading to obtain the biggest speed of cooling of the molten metal. The main wear type appearing during the research, was the abrasion and adhesive wear.

  19. RJHS Vol 5(2) SOS.cdr

    African Journals Online (AJOL)

    ABEOLUGBENGAS

    reactivity associated ... up-regulated in the exchange vs conducting villi (p = 0.0001), irrespective of the pregnancy type and HIV status. ... Lymphatic vascular endothelial hyaluronan receptor-1 immunoexpression in placenta of HIV infected.

  20. Mixed spin-3/2 and spin-5/2 Ising system on the Bethe lattice

    Energy Technology Data Exchange (ETDEWEB)

    Albayrak, Erhan [Erciyes University, Department of Physics, 38039 Kayseri (Turkey)]. E-mail: albayrak@erciyes.edu.tr; Yigit, Ali [Erciyes University, Department of Physics, 38039 Kayseri (Turkey)

    2006-04-24

    In order to study the critical behaviors of the half-integer mixed spin-3/2 and spin-5/2 Blume-Capel Ising ferrimagnetic system, we have used the exact recursion relations on the Bethe lattice. The system was studied for the coordination numbers with q=3, 4, 5 and 6, and the obtained phase diagrams are illustrated on the (kT{sub c}/|J|,D{sub A}/|J|) plane for constant values of D{sub B}/|J|, the reduced crystal field of the sublattice with spin-5/2, and on the (kT{sub c}/|J|,D{sub B}/|J|) plane for constant values of D{sub A}/|J|, the reduced crystal field of the sublattice with spin-3/2, for q=3 only, since the cases corresponding to q=4, 5 and 6 reproduce results similar to the case for q=3. In addition we have also presented the phase diagram with equal strengths of the crystal fields for q=3, 4, 5 and 6. Besides the second- and first-order phase transitions, the system also exhibits compensation temperatures for appropriate values of the crystal fields. In this mixed spin system while the second-order phase transition lines never cut the reduced crystal field axes as in the single spin type spin-3/2 and spin-5/2 Ising models separately, the first-order phase transition lines never connect to the second-order phase transition lines and they end at the critical points, therefore the system does not give any tricritical points. In addition to this, this mixed-spin model exhibits one or two compensation temperatures depending on the values of the crystal fields, as a result the compensation temperature lines show reentrant behavior.

  1. Probing bulk physics in the 5/2 fractional quantum Hall effect using the Corbino geometry

    Science.gov (United States)

    Schmidt, Benjamin; Bennaceur, Keyan; Bilodeau, Simon; Gaucher, Samuel; Lilly, Michael; Reno, John; Pfeiffer, Loren; West, Ken; Reulet, Bertrand; Gervais, Guillaume

    We present two- and four-point Corbino geometry transport measurements in the second Landau level in GaAs/AlGaAs heterostructures. By avoiding edge transport, we are able to directly probe the physics of the bulk quasiparticles in fractional quantum Hall (FQH) states including 5/2. Our highest-quality sample shows stripe and bubble phases in high Landau levels, and most importantly well-resolved FQH minima in the second Landau level. We report Arrhenius-type fits to the activated conductance, and find that σ0 agrees well with theory and existing Hall geometry data in the first Landau level, but not in the second Landau level. We will discuss the advantages the Corbino geometry could bring to various experiments designed to detect the non-Abelian entropy at 5/2, and our progress towards realizing those schemes. The results of these experiments could complement interferometry and other edge-based measurements by providing direct evidence for non-Abelian behaviour of the bulk quasiparticles. Sandia National Laboratories is a multi-program laboratory managed and operated by Sandia Corporation, a wholly owned subsidiary of Lockheed Martin Corporation, for the U.S. Department of Energy's National Nuclear Security Administration under Contract DE-AC04-94AL8500.

  2. 7,8,15,16-tetraoxa-dispiro[5.2.5.2]hexadecane-3-carboxylic acid derivatives and their antimalarial activity

    Directory of Open Access Journals (Sweden)

    BOGDAN SOLAJA

    2004-11-01

    Full Text Available Several C2 symmetrical mixed tetraoxanes were prepared starting from a gemdihydroperoxide and a ketone. The obtained tetraoxanes showed pronounced antimalarial activity against P. falciparum chloroquine resistant W2 and chloroquine susceptible D6 strains, with N-(2-dimethylaminoethyl-7,8,15,16-tetraoxa-dispiro[5.2.5.2] hexadecane-3-carboxamide being as active as artemisinin.

  3. Mixed spin-2 and spin-5/2 Blume-Capel model

    Energy Technology Data Exchange (ETDEWEB)

    Yigit, A. [Erciyes University, Department of Physics, 38039 Kayseri (Turkey); Albayrak, E. [Erciyes University, Department of Physics, 38039 Kayseri (Turkey)], E-mail: albayrak@erciyes.edu.tr

    2008-01-21

    The influence of increasing the coordination number q on the phase diagrams of the mixed spin-2 and spin-5/2 Blume-Capel Ising ferrimagnetic system with two crystal-field interactions, D{sub A} for spin-2 and D{sub B} for spin-5/2 , is investigated on the Bethe lattice by using the exact recursion equations. The phase diagrams are obtained for the case with equal crystal field strengths when q=3, 4 and 6 on the (kT/|J|,D/|J|) planes and for the case with unequal crystal field strengths on the (kT/|J|,D{sub A}/|J|) and (kT/|J|,D{sub B}/|J|) planes for various values of D{sub B}/|J| and D{sub A}/|J|, respectively, for q=4 and 6. Besides the second-order lines, the model presents three types of first-order phase transition lines; one of them ends on the compensation lines (q=3), the other one ends at a critical end point (q=4) and last one terminates at a tricritical point (q=6) for the case with equal crystal field strengths. In this case we have also observed up to four compensation temperatures when q=6. Besides the second-order, tricritical and compensation lines, the system presents two types of the first-order lines one of them ending at a tricritical point and the other one ending at an isolated point when unequal crystal field values are taken.

  4. UV and cold tolerance of a pigment-producing Antarctic Janthinobacterium sp. Ant5-2

    KAUST Repository

    Mojib, Nazia

    2013-03-20

    In this paper, we describe the UV and cold tolerance of a purple violet pigment (PVP)-producing Antarctic bacterium, Janthinobacterium sp. Ant5-2 (PVP+) and compared its physiological adaptations with a pigmentless mutant strain (PVP-). A spontaneous deletion of vioA that codes for tryptophan monooxygenase, the first gene involved in the biosynthesis of PVP was found in PVP- strain. The PVP- culture exhibited significantly reduced survival during exponential and stationary growth phase following exposure to UVB (320 nm) and UVC (254 nm) (dose range: 0-300 J/m2) when compared to wild-type (PVP+) cultures. In addition, upon biochemical inhibition of pigment synthesis by 2(5H)-furanone, wild-type PVP+ cultures exhibited approximately 50-fold growth reduction at a higher dose (300 J/m2) of UV. Increased resistance to UV was observed upon inducing starvation state in both PVP+ and PVP- cultures. There was 80 % (SD = ±8) reduction in extrapolymeric substance (EPS) production in the PVP- cultures along with a compromised survival to freeze-thaw cycles when compared to the PVP+ cultures. Perhaps synthesis of PVP and EPS are among the key adaptive features that define the survival of this bacterium in Antarctic extreme conditions, especially during austral summer months. © 2013 Springer Japan.

  5. UV and cold tolerance of a pigment-producing Antarctic Janthinobacterium sp. Ant5-2.

    Science.gov (United States)

    Mojib, Nazia; Farhoomand, Amin; Andersen, Dale T; Bej, Asim K

    2013-05-01

    In this paper, we describe the UV and cold tolerance of a purple violet pigment (PVP)-producing Antarctic bacterium, Janthinobacterium sp. Ant5-2 (PVP(+)) and compared its physiological adaptations with a pigmentless mutant strain (PVP(-)). A spontaneous deletion of vioA that codes for tryptophan monooxygenase, the first gene involved in the biosynthesis of PVP was found in PVP(-) strain. The PVP(-) culture exhibited significantly reduced survival during exponential and stationary growth phase following exposure to UVB (320 nm) and UVC (254 nm) (dose range: 0-300 J/m²) when compared to wild-type (PVP(+)) cultures. In addition, upon biochemical inhibition of pigment synthesis by 2(5H)-furanone, wild-type PVP(+) cultures exhibited approximately 50-fold growth reduction at a higher dose (300 J/m²) of UV. Increased resistance to UV was observed upon inducing starvation state in both PVP(+) and PVP(-) cultures. There was 80% (SD = ±8) reduction in extrapolymeric substance (EPS) production in the PVP(-) cultures along with a compromised survival to freeze-thaw cycles when compared to the PVP(+) cultures. Perhaps synthesis of PVP and EPS are among the key adaptive features that define the survival of this bacterium in Antarctic extreme conditions, especially during austral summer months.

  6. Overview and Evaluation of the Community Multiscale Air Quality (CMAQ) Modeling System Version 5.2

    Science.gov (United States)

    A new version of the Community Multiscale Air Quality (CMAQ) model, version 5.2 (CMAQv5.2), is currently being developed, with a planned release date in 2017. The new model includes numerous updates from the previous version of the model (CMAQv5.1). Specific updates include a new...

  7. Competing ν = 5/2 fractional quantum Hall states in confined geometry.

    Science.gov (United States)

    Fu, Hailong; Wang, Pengjie; Shan, Pujia; Xiong, Lin; Pfeiffer, Loren N; West, Ken; Kastner, Marc A; Lin, Xi

    2016-11-01

    Some theories predict that the filling factor 5/2 fractional quantum Hall state can exhibit non-Abelian statistics, which makes it a candidate for fault-tolerant topological quantum computation. Although the non-Abelian Pfaffian state and its particle-hole conjugate, the anti-Pfaffian state, are the most plausible wave functions for the 5/2 state, there are a number of alternatives with either Abelian or non-Abelian statistics. Recent experiments suggest that the tunneling exponents are more consistent with an Abelian state rather than a non-Abelian state. Here, we present edge-current-tunneling experiments in geometrically confined quantum point contacts, which indicate that Abelian and non-Abelian states compete at filling factor 5/2. Our results are consistent with a transition from an Abelian state to a non-Abelian state in a single quantum point contact when the confinement is tuned. Our observation suggests that there is an intrinsic non-Abelian 5/2 ground state but that the appropriate confinement is necessary to maintain it. This observation is important not only for understanding the physics of the 5/2 state but also for the design of future topological quantum computation devices.

  8. The October 20, 2006 Manyas (ML=5.2 and October 24, 2006 Gemlik (ML=5.2 earthquakes in the Marmara region (NW Turkey: ground motion characteristics

    Directory of Open Access Journals (Sweden)

    Esref Yalcinkaya

    2015-03-01

    Full Text Available In this study, we analyze the ground motion characteristics of October 20, 2006 Manyas (ML=5.2 and October 24, 2006 Gemlik (ML=5.2 earthquakes. Both earthquakes occurred on the southern branch of the North Anatolian Fault Zone in Marmara region, which has a lower seismic hazard relative to the northern branch. The two events are the largest earthquakes on the southern branch recorded by a modern and vast seismological network; therefore their records are valuable to evaluate seismic risk of the region and the understanding of physics of wave propagation. The analysis show that the attenuation of PGAs is very similar for two earthquakes, but they are not represented by the empirical relation obtained for earthquakes occurred on the northern branch. The waveforms of the Gemlik earthquake recorded by BYTNet array indicate an EW rupture orientation with right-lateral slip which fits to the general character of the southern branch. Ground motions at the stations located within basin are strongly influenced by the presence of locally induced surface waves resulting in lengthening of significant shaking duration with respect to a nearby ridge site. Surface wave characteristics are very similar for the Manyas and Gemlik earthquakes, but variations are observed on components which may be related to 3D basin geometry. Resonance frequencies of the surface waves generated within basin are very close to the 1D site resonances at the stations obtained from H/V ratios of S waves. The resonance frequency is about 0.2 Hz within the large Bursa Plain, whereas it increases to about 0.9 Hz within the smaller Gemlik Plain.

  9. 10 CFR 960.5-2-1 - Population density and distribution.

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 4 2010-01-01 2010-01-01 false Population density and distribution. 960.5-2-1 Section 960... Population density and distribution. (a) Qualifying condition. The site shall be located such that, during... specified in § 960.5-1(a)(1). (b) Favorable conditions. (1) A low population density in the general region...

  10. PHASIM, a sophisticated phased array antenna software simulator implemented in MATLAB 5.2

    NARCIS (Netherlands)

    Keizer, W.P.M.N.

    1999-01-01

    A sophisticated phased array simulator software package for the design and analysis of planar phased array antennas is presented. This simulator is coded in MATLAB version 5.2. Using MATLAB, numerical engineering problems can be solved in a fraction of time of time required by programs coded in

  11. Landau Level Mixing and the Ground State of the ν=5/2 Quantum Hall Effect.

    Science.gov (United States)

    Rezayi, Edward H

    2017-07-14

    Inter-Landau-level transitions break particle hole symmetry and will choose either the Pfaffian or the anti-Pfaffian state as the absolute ground state at 5/2 filling of the fractional quantum Hall effect. An approach based on truncating the Hilbert space has favored the anti-Pfaffian. A second approach based on an effective Hamiltonian produced the Pfaffian. In this Letter, perturbation theory is applied to finite sizes without bias to any specific pseudopotential component. This method also singles out the anti-Pfaffian. A critical piece of the effective Hamiltonian, which was absent in previous studies, reverts the ground state at 5/2 to the anti-Pfaffian.

  12. Modified Sierpinski Gasket Patch Antenna for UMTS and 2.4/5.2 WLAN

    Directory of Open Access Journals (Sweden)

    Y. E. Ali

    2013-05-01

    Full Text Available A modified Sierpinski Gasket fractal antenna for multiband application is proposed in this paper. The modified ground plane and the microstrip feed are used to obtain the wider bandwidth at the resonance frequency. The antenna is designed and printed on two layers FR-4 substrate (ϵr=4.4 and h=1.6 mm to cover the UMTS and 2.4/5.2 WLAN. The radiation pattern of the proposed antenna is similar to an omnidirectional. The proposed antenna has maximum gain of 1.88, 1.6, 4.31 dB at 2, 2.4, 5.2 GHz, respectively The properties of the antenna such as return losses, radiation pattern, input resistance and gain are determined via numerical CST Microwave Studio 2010 software.

  13. Attainment of ?5-2-1-0? obesity recommendations in preschool-aged children

    OpenAIRE

    Khalsa, Amrik Singh; Kharofa, Roohi; Ollberding, Nicholas J.; Bishop, Laurie; Copeland, Kristen A.

    2017-01-01

    Obesity prevention guidelines recommend children eat ??5 servings of fruits and vegetables, view ??2?h of screen time, participate in 1?h of physical activity, and consume 0 sugar-sweetened beverages daily, commonly known as ?5-2-1-0?. We sought to determine: the extent to which preschool-aged children attending child care meet these guidelines, predictors of attainment, and associations of attainment with weight status. We analyzed in 2016, 24-hour dietary, physical activity, and screen time...

  14. 16QAM transmission with 5.2 bits/s/Hz spectral efficiency over transoceanic distance.

    Science.gov (United States)

    Zhang, H; Cai, J-X; Batshon, H G; Davidson, C R; Sun, Y; Mazurczyk, M; Foursa, D G; Pilipetskii, A; Mohs, G; Bergano, Neal S

    2012-05-21

    We transmit 160 x 100 G PDM RZ 16 QAM channels with 5.2 bits/s/Hz spectral efficiency over 6,860 km. There are more than 3 billion 16 QAM symbols, i.e., 12 billion bits, processed in total. Using coded modulation and iterative decoding between a MAP decoder and an LDPC based FEC all channels are decoded with no remaining errors.

  15. Neutron occupancy of 0d5/2 orbital in 24O

    Directory of Open Access Journals (Sweden)

    Tshoo K.

    2014-03-01

    Full Text Available The partial one-neutron removal cross section of 24O leading to the first excited state in 23O has been measured to be 65.7 ± 5.3 mb with a proton target in inverse kinematics at the beam energy of 62 MeV/nucleon. The decay energy spectrum of the neutron unbound state of 23O was reconstructed from the measured four momenta of 22O and the emitted neutron. A sharp peak was observed at Edecay = 48 ± 3 keV, confirming the previous measurements. The measured partial longitudinal momentum distribution of 23O* showed the d-wave knockout character, providing a support for the Jπ assignment of 5/2+ for this state. The spectroscopic factor for the neutrons in 0d5/2 orbital was deduced, for the first time, to be C2S(0d5/2 = 3.7 ± 0.3 (preliminary by comparing with the result of Glauber model. The relatively large spectroscopic factor supports the N = 16 shell closure in the neutron drip-line nucleus 24O.

  16. 17 CFR 240.10b5-2 - Duties of trust or confidence in misappropriation insider trading cases.

    Science.gov (United States)

    2010-04-01

    ... in misappropriation insider trading cases. 240.10b5-2 Section 240.10b5-2 Commodity and Securities... Devices and Contrivances § 240.10b5-2 Duties of trust or confidence in misappropriation insider trading... of insider trading under Section 10(b) of the Act and Rule 10b-5. The law of insider trading is...

  17. Diaquabis[5-(2-pyridyltetrazolato-κ2N1,N5]iron(II

    Directory of Open Access Journals (Sweden)

    Min Hu

    2009-04-01

    Full Text Available The title complex, [Fe(C6H4N52(H2O2], was synthesized by the reaction of ferrous sulfate with 5-(2-pyridyl-2H-tetrazole (HL. The FeII atom, located on a crystallographic center of inversion, is coordinated by four N-atom donors from two planar trans-related deprotonated L ligands and two O atoms from two axial water molecules in a distorted octahedral geometry. The FeII mononuclear units are further connected by intermolecular O—H...N and C—H...O hydrogen-bonding interactions, forming a three-dimensional framework.

  18. Spin 3/2 and 5/2 nucleon resonances in kaon electroproduction

    Energy Technology Data Exchange (ETDEWEB)

    Mart, T. [Departemen Fisika, FMIPA, Universitas Indonesia, Kampus UI Depok (Indonesia)

    2016-04-19

    We have analyzed the available kaon electroproduction data by using the field theoretical approach involving spin 3/2 and 5/2 nucleon resonances. To this end we extend our previous isobar model for photoproduction to the finite Q{sup 2} region by making use of different electromagnetic form factors. The result indicates that kaon electroproduction data can be nicely described by the photoproduction isobar model, provided that the inserted electromagnetic form factors in all electromagnetic vertices are constructed from a combination of dipole and exponential form factors is included in all electromagnetic vertices.

  19. P5.2-8 Technical guide to map and describe wildland-urban interfaces (WUIs)

    OpenAIRE

    Lampin-Maillet, C.; Bouillon, C.; Long, M; Morge, D.; Jappiot, M.; Herrero, G.; Galiana, L.; Mantzavelas, A.

    2009-01-01

    This guide presents a method for wildland-urban interface mapping, applied to large areas, at a large scale. This method can be adapted easily to specific situations observed in different European countries. The guide is based on a combination of four housing configuration types and three types of horizontal structure of vegetation. Twelve wildland-urban interface types have been produced. It is particularly well adapted to the French environment, but the method has also been well adapted (an...

  20. Computation of Estonian CORS data using Bernese 5.2 and Gipsy 6.4 softwares

    Science.gov (United States)

    Kollo, Karin; Kall, Tarmo; Liibusk, Aive

    2017-04-01

    GNSS permanent station network in Estonia (ESTREF) was established already in 2007. In 2014-15 extensive reconstruction of ESTREF was carried out, including the establishment of 18 new stations, change of the hardware in CORS stations as well as establishing GNSS-RTK service for the whole Estonia. For GNSS-RTK service one needs precise coordinates in well-defined reference frame, i.e., ETRS89. For long time stability of stations and time-series analysis the re-processing of Estonian CORS data is ongoing. We re-process data from 2007 until 2015 with program Bernese GNSS 5.2 (Dach, 2015). For the set of ESTREF stations established in 2007, we perform as well computations with GIPSY 6.4 software (Ries et al., 2015). In the computations daily GPS-only solution was used. For precise orbits, final products from CODE (CODE analysis centre at the Astronomical Institute of the University of Bern) and JPL (Jet Propulsion Laboratory) for Bernese and GIPSY solutions were used, respectively. The cut-off angle was set to 10 degrees in order to avoid near-field multipath influence. In GIPSY, precise point positioning method with fixing ambiguities was used. Bernese calculations were performed based on double difference processing. Antenna phase centers were modelled based on igs08.atx and epnc_08.atx files. Vienna mapping function was used for mapping tropospheric delays. For the GIPSY solution, the higher order ionospheric term was modelled based on IRI-2012b model. For the Bernese solution higher order ionospheric term was neglected. FES2004 ocean tide loading model was used for the both computation strategies. As a result, two solutions using different scientific GNSS computation programs were obtained. The results from Bernese and GIPSY solutions were compared, using station repeatability values, RMS and coordinate differences. KEYWORDS: GNSS reference station network, Bernese GNSS 5.2, Gipsy 6.4, Estonia. References: Dach, R., S. Lutz, P. Walser, P. Fridez (Eds); 2015

  1. Orphan Spins in the S =5/2 Antiferromagnet CaFe2O4

    Science.gov (United States)

    Stock, C.; Rodriguez, E. E.; Lee, N.; Demmel, F.; Fouquet, P.; Laver, M.; Niedermayer, Ch.; Su, Y.; Nemkovski, K.; Green, M. A.; Rodriguez-Rivera, J. A.; Kim, J. W.; Zhang, L.; Cheong, S.-W.

    2017-12-01

    CaFe2O4 is an anisotropic S =5/2 antiferromagnet with two competing A (↑↑↓↓) and B (↑↓↑↓) magnetic order parameters separated by static antiphase boundaries at low temperatures. Neutron diffraction and bulk susceptibility measurements, show that the spins near these boundaries are weakly correlated and a carry an uncompensated ferromagnetic moment that can be tuned with a magnetic field. Spectroscopic measurements find these spins are bound with excitation energies less than the bulk magnetic spin waves and resemble the spectra from isolated spin clusters. Localized bound orphaned spins separate the two competing magnetic order parameters in CaFe2 O4 .

  2. Solitary Magnons in the S =5/2 Antiferromagnet CaFe2O4

    Science.gov (United States)

    Stock, C.; Rodriguez, E. E.; Lee, N.; Green, M. A.; Demmel, F.; Ewings, R. A.; Fouquet, P.; Laver, M.; Niedermayer, Ch.; Su, Y.; Nemkovski, K.; Rodriguez-Rivera, J. A.; Cheong, S.-W.

    2016-07-01

    CaFe2O4 is a S =5/2 anisotropic antiferromagnet based upon zig-zag chains having two competing magnetic structures, denoted as the A (↑↑↓↓) and B (↑↓↑↓) phases, which differ by the c -axis stacking of ferromagnetic stripes. We apply neutron scattering to demonstrate that the competing A and B phase order parameters result in magnetic antiphase boundaries along c which freeze on the time scale of ˜1 ns at the onset of magnetic order at 200 K. Using high resolution neutron spectroscopy, we find quantized spin wave levels and measure 9 such excitations localized in regions ˜1 - 2 c -axis lattice constants in size. We discuss these in the context of solitary magnons predicted to exist in anisotropic systems. The magnetic anisotropy affords both competing A +B orders as well as localization of spin excitations in a classical magnet.

  3. Orphan Spins in the S=5/2 Antiferromagnet CaFe_{2}O_{4}.

    Science.gov (United States)

    Stock, C; Rodriguez, E E; Lee, N; Demmel, F; Fouquet, P; Laver, M; Niedermayer, Ch; Su, Y; Nemkovski, K; Green, M A; Rodriguez-Rivera, J A; Kim, J W; Zhang, L; Cheong, S-W

    2017-12-22

    CaFe_{2}O_{4} is an anisotropic S=5/2 antiferromagnet with two competing A (↑↑↓↓) and B (↑↓↑↓) magnetic order parameters separated by static antiphase boundaries at low temperatures. Neutron diffraction and bulk susceptibility measurements, show that the spins near these boundaries are weakly correlated and a carry an uncompensated ferromagnetic moment that can be tuned with a magnetic field. Spectroscopic measurements find these spins are bound with excitation energies less than the bulk magnetic spin waves and resemble the spectra from isolated spin clusters. Localized bound orphaned spins separate the two competing magnetic order parameters in CaFe_{2}O_{4}.

  4. Aftershock Study of the 2014 Duncan, Arizona Mw = 5.2 Earthquake Using Local Seismic Data

    Science.gov (United States)

    Dorn, K. M.; Young, J.; Barstow, N.; Peavey, H.; Braunmiller, J.

    2016-12-01

    On June 29, 2014, at 4:59:35.4 UTC, a Mw = 5.2 earthquake struck near Duncan, just west of the Arizona-New Mexico border. This event is the strongest instrumentally recorded earthquake yet in southeastern Arizona, which experiences low seismicity due to slow roughly east-west-trending extension in the transition zone between the Basin and Range region and the stable Colorado Plateau to the north. An approximately 15-by-20-km-wide temporary network of four short-period and two broadband seismometers was deployed to study the aftershock sequence, as the nearest permanent stations are located over one hundred kilometers away. We used the BRTT Antelope "dbdetect" and "dbgrassoc" tools to obtain locations for about 10,000 aftershocks from July 8 through August 28, 2014, when at least four local stations were operational. Our preliminary results suggest that most of the activity occurred in a north-south-elongated area, within 32.57-32.64° N and 109.11-109.15° W and about 4-7 km deep. We have not observed distinct event migrations, but found several event clusters within the aftershock region that were active for short time periods, implying a complex pattern of strain release. The aftershock sequence has continued for more than two years after the mainshock event.

  5. Solitary Magnons in the S=5/2 Antiferromagnet CaFe_{2}O_{4}.

    Science.gov (United States)

    Stock, C; Rodriguez, E E; Lee, N; Green, M A; Demmel, F; Ewings, R A; Fouquet, P; Laver, M; Niedermayer, Ch; Su, Y; Nemkovski, K; Rodriguez-Rivera, J A; Cheong, S-W

    2016-07-01

    CaFe_{2}O_{4} is a S=5/2 anisotropic antiferromagnet based upon zig-zag chains having two competing magnetic structures, denoted as the A (↑↑↓↓) and B (↑↓↑↓) phases, which differ by the c-axis stacking of ferromagnetic stripes. We apply neutron scattering to demonstrate that the competing A and B phase order parameters result in magnetic antiphase boundaries along c which freeze on the time scale of ∼1  ns at the onset of magnetic order at 200 K. Using high resolution neutron spectroscopy, we find quantized spin wave levels and measure 9 such excitations localized in regions ∼1-2 c-axis lattice constants in size. We discuss these in the context of solitary magnons predicted to exist in anisotropic systems. The magnetic anisotropy affords both competing A+B orders as well as localization of spin excitations in a classical magnet.

  6. 5-(2-amimo-4-styryl pyrimidine-4-yl-4-methoxybenzofuran-6-ol

    Directory of Open Access Journals (Sweden)

    Atteyat A Labib

    2013-05-01

    Full Text Available This study describes the organic synthesis of 5-(2-amimo-4-styryl pyrimidine-4-yl-4-methoxy benzofuran-6-ol (SPBF as an example of a benzofuran derivative used as a new series of amyloid imaging agents. These benzofuran derivatives may be useful amyloid imaging agents for detecting B-amyloid plagues in the brain of Alzheimer’s disease. The precursor is 1-[6-hydroxy-4-methoxybenzofuran-5-yl]-phenyl butadiene ketone, which react with guanidine hydrochloride. The purification process was done via crystallization using solvent ethanol. The overall yield was 75% and the structure of the synthesized compound was confirmed by correct analytical and spectral data. Also, The synthesized compound was labeled with radioactive iodine -125 via electrophilic substitution reaction, in the presence of iodogen as an oxidizing agent, the labeling process was carried out at 95oC for 20min. The radiochemical yield was determined by using a thin layer chromatography and the yield was equal to 80%. Preliminary an in-vivo study examined normal mice after intravenous injection through the tail vein and the data showed the labeling compound was quickly cleared from most body organs. The radioiodinated compound showed high brain uptake.The results of this study suggest that radioiodinated (SPBF may be useful as a brain imaging agents.

  7. LAPUR5.2 Verification and User's Manual

    Energy Technology Data Exchange (ETDEWEB)

    Escriva, A.

    2001-02-26

    This report documents a series of programming upgrades to increase the available number of thermal-hydraulic regions (i.e., channels) and other parameters in LAPUR. LAPUR, a computer program in FORTRAN, is a mathematical description of the core of a boiling water reactor. Its two linked modules, LAPURX and LAPURW, respectively solve the steady state governing equations for the coolant and fuel and the dynamic equations for the coolant, fuel, and neutron field in the frequency domain. General implementation descriptions are followed by a detailed description of input and output parameters of LAPURX and LAPURW. Sample inputs are included and stability benchmarks are noted. The original version of LAPUR was limited to seven channels; the current version, LAPUR 5.2, has been verified with up to 200 channels, each of which can have its own axial and radial power shape. Other significant parameter upgrade is the calculation of the transfer functions for up to 100 frequencies. All code dimensions are now parameterized and can be increased if necessary.

  8. Expression of CK7, Cam 5.2 and Ber-Ep4 in cutaneous squamous cell carcinoma.

    Science.gov (United States)

    Clarke, Loren E; Conway, Andrea B; Warner, Nicole M; Barnwell, Patricia N; Sceppa, Jennifer; Helm, Klaus F

    2013-07-01

    Cytokeratin 7 (CK7) and Cam 5.2 are often used to differentiate extramammary Paget's disease (EPD) from squamous cell carcinoma (SCC) in situ because they are generally considered to be expressed in the former but not in the latter. However, we have encountered CK7+ and Cam 5.2+ SCCs. We evaluated CK7, Cam 5.2 and Ber-Ep4 expression in SCC and EPD. We found significant CK7 and Cam 5.2 positivity in SCCs, particularly in those with a pagetoid pattern. Only one case expressed Ber-Ep4. We conclude that CK7 and Cam 5.2 expression may occur in SCC. A panel including Ber-Ep4 is advisable for immunohistochemical differentiation of EPD from SCC. © 2013 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  9. Inhibition of 3,5,2',4'-Tetrahydroxychalcone on Production of Uric Acid in Hypoxanthine-Induced Hyperuricemic Mice.

    Science.gov (United States)

    Niu, Yanfen; Zhou, Yuanfang; Lin, Hua; Gao, Li-Hui; Xiong, Wenyong; Zhu, Huajie; Zou, Cheng-Gang; Li, Ling

    2018-01-01

    The mechanism of 3,5,2',4'-tetrahydroxychalcone on lowing urate level is still unknown. Here we investigated the effects of 3,5,2',4'-tetrahydroxychalcone on urate levels, xanthine oxidase/xanthine dehydrogenase (XOD/XDH) activities in hypoxanthine-induced hyperuricemic mice, as well as the effects of 3,5,2',4'-tetrahydroxychalcone on the mRNA expression levels and content of phosphoribosyl pyrophosphate synthetase (PRPS), phosphoribosyl pyrophosphate amidotransferase (PRPPAT) and hypoxanthine-guanine phosphoribosyl transferase (HGPRT). Our results demonstrated that 3,5,2',4'-tetrahydroxychalcone (1.0, 2.0, and 4.0 mg/kg) reduced the uric acid levels in serum of the hyperuricemic mice in dose- and time-dependent manners. The activities of XOD/XDH in serum and liver were also significantly inhibited by 3,5,2',4'-tetrahydroxychalcone; In addition, 3,5,2',4'-tetrahydroxychalcone decreased the mRNA expression of HGPRT in brain and content of PRPS and PRPPAT in liver. These findings demonstrated that 3,5,2',4'-tetrahydroxychalcone suppresses uric acid production by affecting the critical enzymes, XOD/XDH, PRPS, PRPPAT and HGPRT in purine nucleotide metabolism.

  10. Monte Carlo simulation of compensation behavior for a mixed spin-5/2 and spin-7/2 Ising system with crystal field interaction

    Science.gov (United States)

    Bahlagui, T.; Bouda, H.; El Kenz, A.; Bahmad, L.; Benyoussef, A.

    2017-10-01

    Monte Carlo simulation has been carried out to study the magnetization of the mixed spin-5/2 and spin-7/2 Ising ferrimagnetic model on a square lattice with periodic boundary conditions. The total magnetization and the magnetizations of the two sublattices under the effects of exchange interactions and the crystal field anisotropy are studied. The ground-state diagrams are constructed. We obtained different types for the thermal dependence of magnetization. Compensation points where the global magnetization of the system vanishes have been detected for appropriate values of the system parameters.

  11. NOAA Climate Data Record (CDR) of Sea Surface Temperature (SST) from AVHRR Pathfinder, Version 5.2

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The AVHRR Pathfinder Version 5.2 Sea Surface Temperature data set (PFV52) is a collection of global, twice-daily 4km sea surface temperature data produced in a...

  12. Localization of Gunfire from Multiple Shooters (ARO Research Topic 5.2, Information Processing and Fusion; STIR Program)

    Science.gov (United States)

    2016-03-03

    2015 Approved for Public Release; Distribution Unlimited Final Report: Localization of Gunfire from Multiple Shooters (ARO Research Topic 5.2... Research Topic 5.2, Information Processing & Fusion; STIR Program) Report Title Soldier-wearable gunfire detection systems (SW-GDS) are important for...AGENCY NAME(S) AND ADDRESS (ES) U.S. Army Research Office P.O. Box 12211 Research Triangle Park, NC 27709-2211 gunfire localization, time of arrival

  13. The influence of conventional tempering on the tribiological resistance of the high speed steel HS 6-5-2 remelted with electric arc

    Directory of Open Access Journals (Sweden)

    A. Dziedzic

    2010-04-01

    Full Text Available The influence of the conventional tempering has been defined in the paper in two different temperatures 560C and 600C on the intensity of tribological wear of the high speed steel HS 6-5-2 remelted with the electric arc. The influence of tempering on the intensity of wear for the steel has been tested with the single and overlapping remeltings. Moreover, the types of the tribological wear appeared during the friction. The tribiological research, were done in the technically dry friction conditions on a testing machine of the pin-on-disc T-01M. Conducting the conventional process of tempering after the remelting with the electric arc, causes the decrease of the intensity of the tribological wear. The smallest intensity of tribiological wear after tempering was observed in the high speed steel HS 6-5-2 with the single remelting of the current 70 A. The main wear type appearing during the research was the abrasion and adhesive wear.

  14. Redetermination of metarossite, CaV5+2O6·2H2O

    Directory of Open Access Journals (Sweden)

    Anaïs Kobsch

    2016-09-01

    Full Text Available The crystal structure of metarossite, ideally CaV2O6·2H2O [chemical name: calcium divanadium(V hexaoxide dihydrate], was first determined using precession photographs, with fixed isotropic displacement parameters and without locating the positions of the H atoms, leading to a reliability factor R = 0.11 [Kelsey & Barnes (1960. Can. Mineral. 6, 448–466]. This communication reports a structure redetermination of this mineral on the basis of single-crystal X-ray diffraction data of a natural sample from the Blue Cap mine, San Juan County, Utah, USA (R1 = 0.036. Our study not only confirms the structural topology reported in the previous study, but also makes possible the refinement of all non-H atoms with anisotropic displacement parameters and all H atoms located. The metarossite structure is characterized by chains of edge-sharing [CaO8] polyhedra parallel to [100] that are themselves connected by chains of alternating [VO5] trigonal bipyramids parallel to [010]. The two H2O molecules are bonded to Ca. Analysis of the displacement parameters show that the [VO5] chains librate around [010]. In addition, we measured the Raman spectrum of metarossite and compared it with IR and Raman data previously reported. Moreover, heating of metarossite led to a loss of water, which results in a transformation to the brannerite-type structure, CaV2O6, implying a possible dehydration pathway for the compounds M2+V2O6·xH2O, with M = Cu, Cd, Mg or Mn, and x = 2 or 4.

  15. Antena doble banda alimentada por proximidad para aplicaciones de WLAN en 2.4 y 5.2 GHz

    National Research Council Canada - National Science Library

    Rodriguez Avila, Dandys; Gonzalez Gutierrez, Elyu; Coto Mederos, Michel; Morante Rizo, Francisco R

    2014-01-01

    .... El dispositivo trabaja en las bandas de 2.4 (2.4-2.485 GHz) y 5.2 (5.15-5.35 GHz) de Will. Para alcanzar la operacion en doble frecuencia, se ha realizado una ranura en forma de herradura en el centro del parche...

  16. Quasiparticle agglomerates and environmental effects in the fractional quantum Hall edge states at ν = 5/2

    Energy Technology Data Exchange (ETDEWEB)

    Braggio, A. [SPIN-CNR, Via Dodecaneso 33, 16146 Genova (Italy); Carrega, M. [NEST, Istituto Nanoscienze-CNR, and Scuola Normale Superiore, I-56126, Pisa (Italy); Ferraro, D.; Magnoli, N. [Dipartimento di Fisica, Università di Genova, Via Dodecaneso 33, 16146 Genova, Italy and INFN, Via Dodecaneso 33, 16146, Genova (Italy); Sassetti, M. [Dipartimento di Fisica, Università di Genova, Via Dodecaneso 33, 16146 Genova, Italy and SPIN-CNR, Via Dodecaneso 33, 16146 Genova (Italy)

    2013-12-04

    We discuss how the presence of environmental effects and quasiparticle agglomerates could better reconcile the edge states theories with the experimental observations for the case of ν = 5/2. The Pfaffian and the anti-Pfaffian models will be compared in connection with experimental results identifying the latter as the best candidate.

  17. Irradiation Effect of Argon Ion on Interfacial Structure Fe(2nm/Si(tsi=0.5-2 nm Multilayer thin Film

    Directory of Open Access Journals (Sweden)

    S. Purwanto

    2010-04-01

    Full Text Available Investigation includes formation of interfacial structure of Fe(2nm/Si(tSi= 0.5-2 nm multilayer thin film and the behavior of antiferromagnetic coupling between Fe layers due to Argon ion irradiation was investigated. [Fe(2nm/Si]30 multilayers (MLs with a thickness of Si spacer 0.5 - 2 nanometer were prepared on n-type (100 Si substrate by the helicon plasma sputtering method. Irradiation were performed using 400keV Ar ion to investigate the behavior of magnetic properties of the Fe/Si MLs. The magnetization measurements of Fe/Si MLs after 400keV Ar ion irradiation show the degradation of antiferromagnetic behavior of Fe layers depend on the ion doses. The Magnetoresistance (MR measurements using by Four Point Probe (FPP method also confirm that MR ratio decrease after ion irradiation. X-ray diffraction (XRD patterns indicate that the intensity of a satellite peak induced by a superlattice structure does not change within the range of ion dose. These results imply that the surface of interface structures after ion irradiation become rough although the layer structures are maintained. Therefore, it is considered that the MR properties of Fe/Si MLs also are due to the metallic superlattice structures such as Fe/Cr and Co/Cu MLs.

  18. The influence of remelting parameters of the electric arc and conventional tempering on the tribological resistance of high speed steel HS 6-5-2

    Directory of Open Access Journals (Sweden)

    A. Dziedzic

    2011-07-01

    Full Text Available The present thesis depicts the results of the research of tribological high speed steel HS 6-5-2 remelted with the electric arc. Steel was remelted with different parameters. The amperage of electric arc was changed, the scanning speed was changed and the single, overlapping remeltings were used. There was also the influence of conventional tempering defined, which was conducted after remelting on the tribological resistance of hardened steel. For the previously mentioned processing variants, the intensity of tribological wear was defined and the linear wear were presented, and the friction coefficients. The type of tribological wear was also given, present during the friction, technically dry, of the hardened steel. The lower intensity of tribological wear was received for the single remelting by electric arc of 50 and 70A. Using the overlapping remeltings for the strengening of the surface layer of the high speed steel HS 6-5-2 causes the increase of the intensity of tribological wear in comparison to the steel with the single remelting. The conventional tempering leads to the decrease of the intensity of tribological wear.

  19. Generation of induced pluripotent stem cells (iPSCs from a Bernard–Soulier syndrome patient carrying a W71R mutation in the GPIX gene

    Directory of Open Access Journals (Sweden)

    Lourdes Lopez-Onieva

    2016-05-01

    Full Text Available We generated an induced pluripotent stem cell (iPSC line from a Bernard–Soulier Syndrome (BSS patient carrying the mutation p.Trp71Arg in the GPIX locus (BSS1-PBMC-iPS4F4. Peripheral blood mononuclear cells (PBMCs were reprogrammed using heat sensitive non-integrative Sendai viruses containing the reprogramming factors Oct3/4, SOX2, KLF4 and c-MYC. Successful silencing of the exogenous reprogramming factors was checked by RT-PCR. Characterization of BSS1-PBMC-iPS4F4 included mutation analysis of GPIX locus, Short Tandem Repeats (STR profiling, alkaline phosphatase enzymatic activity, analysis of conventional pluripotency-associated factors at mRNA and protein level and in vivo differentiation studies. BSS1-PBMC-iPS4F4 will provide a powerful tool to study BSS.

  20. Evaluation of dimensional stability of Iralgin and Alginoplast alginates after disinfection by sodium hypochlorite (5.2% with immersion and spraying methods

    Directory of Open Access Journals (Sweden)

    Vojdani M

    2006-01-01

    Full Text Available Background and Aim: Infection control is an integral part of dentistry and dental impressions are considered an important issue in cross contamination. The aim of this study was to investigate the dimensional stability of two irreversible hydrocolloid materials, Alginoplast and Iralgin after disinfection with 5.2% sodium hypochlorite, used with immersion and spraying methods. Material and Methods: In this experimental study, impressions were made of a master mandibular arch (Typodont containing three stainless steel inserts on the occlucal surface of both mandibular first molars and in the lingual surface of the mandibular central incisors, which served as reference marks for making measurements. Two types of irreversible hydrocolloid (Iralgin and Alginoplast were tested. 5.2% sodium hypochlorite was used in two methods of spraying and immersion to disinfect the samples. The control group was not disinfected. Casts were made of type III gypsum. Stone casts were measured with a Nikon profile projector.Kruskall-Wallis and Mann-Witney test were used for statistical analysis using p<0.05 as the limit of significance. Results: Casts prepared from Alginoplast disinfected by spraying method, were 0.38 % larger in anteroposterior and 0.06% smaller in cross arch dimensions, whereas those prepared from Alginoplast immersed in hypochlorite were 0.47% larger in anteroposterior and 0.11% smaller in cross arch dimensions. Casts made from Iralgin were smaller after both methods of disinfecting, (0.01% smaller in anteroposterior and 0.001% smaller in cross-arch dimensions after spraying and 0.04% smaller in anteroposterior and 0.03% smaller in cross-arch dimensions after immersing in sodium hypochlorite. Conclusion: Alginoplast and Iralgin impressions can be immersed or sprayed for disinfection without compromising the accuracy needed for diagnostic and opposing casts, as well as removable partial denture construction.

  1. A stability study of asteroid families near the 3:1 and 5:2 resonance with Jupiter

    Science.gov (United States)

    Hahn, G.; Lagerkvist, C.-I.; Lindblad, B. A.

    1993-06-01

    The stability and homogeneity of three asteroid families from Lindblad's list (1992) are studied using numerical integration techniques. These families include the Maria family, which lies close to the 3:1 mean motion resonance with Jupiter, the Oppavia-Gefion, and Dora families which are close to the 5:2 resonance. The study is based on a simplified solar system model, which takes into account the perturbations only by Jupiter and Saturn, and Everhart's variable stepsize integrator RA15. Preliminary results indicate that the stability of the orbits of all family members are not affected by the proximity to the 3:1 and 5:2 mean motion resonance with Jupiter.

  2. Magnetic properties and Binder cumulants of a mixed spin-2 and spin-5/2 Ising diamond chain

    Science.gov (United States)

    Jabar, A.; Masrour, R.; Benyoussef, A.; Hamedoun, M.

    2017-11-01

    The mixed spin-2 and spin-5/2 Ising diamond chain is studied using Monte Carlo simulation. The thermal variation of magnetization and magnetic susceptibilities are obtained in diamond chain. The values of transition temperatures of a mixed spin-2 and spin-5/2 Ising diamond chain have been obtained for different sizes of system N, for different crystal field and for different exchange interactions. The Binder cumulant of magnetization 〈M〉 is investigated. The magnetization with the crystal field and the exchange interaction has been established. The magnetic hysteresis cycle is determined for different values of the crystal field, exchange interactions and temperatures. The system presents the superparamagnetic behavior for a fixed crystal field and temperature value.

  3. Co-oligomers Based on 2-Methoxy, 5-(2’-ethylhexyloxy) phenylene and Thienylenevinylene for Organic Solar Cells

    OpenAIRE

    A. El Alamy; mohamed bouzzine; Hamidi, M.; Bouachrine, M.

    2016-01-01

    Thanks to their optoelectronic properties and specific applications such as organic solar cells, the research on the lower band gap of organic p-conjugated materials encompassing both polymers and oligomers have been widely studied over the last years. The control of the band gap of these materials is a research issue of ongoing interest. In this study, theoretical study using the DFT method on four oligomers based on 2-methoxy, 5-(2’-ethylhexyloxy) phenylene and thienylenevinylene is reporte...

  4. Quality Assurance statistics for AVHRR Pathfinder Version 5.2 L3-Collated (L3C) sea surface temperature in global and selected regions (NODC Accession 0111871)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — These quality monitoring data for Pathfinder Version 5.2 (PFV5.2) Sea Surface Temperature (SST) are based on the concept of a Rich Inventory developed by the...

  5. Thermoelectric behaviour of (Bi 0.5Sb 0.5) 2Te 3 semiconducting alloy thin films

    Science.gov (United States)

    Damodara Das, V.; Chandra Mallik, Ramesh

    2001-10-01

    The Jain-Verma theory has been applied to the thermoelectric data of vacuum flash-evaporated and annealed polycrystalline thin films of (Bi 0.5Sb 0.5) 2Te 3 alloys of different thicknesses to study the nature of principal carrier scattering mechanism and also to know the extent of other scattering mechanisms, simultaneously. It is found that the value of the energy dependent scattering index parameter lies between -0.45 and -0.4. This indicates that, even though the principal scattering mechanism in the films is the normal lattice scattering, other scattering like 'impurity' scattering, surface scattering and grain boundary scattering may be present.

  6. Magnetic correlations in the 2D S=5/2 honeycomb antiferromagnet MnPS3

    DEFF Research Database (Denmark)

    Rønnow, H.M.; Wildes, A.R.; Bramwell, S.T.

    2000-01-01

    MnPS3 is a quasi-2D S = 5/2 antiferromagnet on a honeycomb lattice. Using an energy integrating neutron scattering technique, we have measured the structure factor S(k) of the instantaneous magnetic fluctuations. The temperature dependence of the correlation length xi follows the Kosterlitz-Thoul......-Thouless prediction with parameters that are consistently described by a Heisenberg system with inter plane coupling J'/'J = 1/405 and weak xy-anisotropy. (C) 2000 Elsevier Science B.V. All rights reserved....

  7. DETERMINATION OF OPTIMAL CONTOURS OF OPEN PIT MINE DURING OIL SHALE EXPLOITATION, BY MINEX 5.2.3. PROGRAM

    Directory of Open Access Journals (Sweden)

    Miroslav Ignjatović

    2013-04-01

    Full Text Available By examination and determination of optimal solution of technological processes of exploitation and oil shale processing from Aleksinac site and with adopted technical solution and exploitation of oil shale, derived a technical solution that optimize contour of the newly defined open pit mine. In the world, this problem is solved by using a computer program that has become the established standard for quick and efficient solution for this problem. One of the computer’s program, which can be used for determination of the optimal contours of open pit mines is Minex 5.2.3. program, produced in Australia in the Surpac Minex Group Pty Ltd Company, which is applied at the Mining and Metallurgy Institute Bor (no. of licenses are SSI - 24765 and SSI - 24766. In this study, authors performed 11 optimization of deposit geo - models in Minex 5.2.3. based on the tests results, performed in a laboratory for soil mechanics of Mining and Metallurgy Institute, Bor, on samples from the site of Aleksinac deposits.

  8. Acute 5-(2-aminopropyl)benzofuran (5-APB) intoxication and fatality: a case report with postmortem concentrations.

    Science.gov (United States)

    McIntyre, Iain M; Gary, Ray D; Trochta, Amber; Stolberg, Susan; Stabley, Robert

    2015-03-01

    A 20-year-old man, a college student, became unresponsive in front of his girlfriend. He was known to consume alcohol and take an unknown drug at some point while in attendance at a local music festival earlier in the day/evening. Upon arrival of emergency personnel, he was noted to be asystolic and apneic. Despite aggressive medical intervention by emergency personnel and at a local hospital emergency room, he was pronounced deceased within 1.25 h of initial medical attention. Postmortem blood initially screened positive for methamphetamine by ELISA. An alkaline drug screen detected 5-(2-aminopropyl)benzofuran (5-APB) which was subsequently confirmed and quantified by a specific GC-MS SIM analysis following solid-phase extraction. Concentrations were determined in the peripheral blood (2.5 mg/L), central blood (2.9 mg/L), liver (16 mg/kg), vitreous (1.3 mg/L), urine (23 mg/L) and gastric contents (6 mg). No other common amphetamine-like compound was detected, although 5-(2-aminopropyl)-2,3-dihydrobenzofuran (5-APDB) was presumptively identified in both peripheral blood and urine. Alcohol, the only other drug identified, was confirmed at a concentration of 0.02% (w/v). © The Author 2014. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  9. Gauge fields emerging from time-reversal symmetry breaking for spin-5/2 fermions in a honeycomb lattice

    Energy Technology Data Exchange (ETDEWEB)

    Szirmai, G.; Szirmai, E. [ICFO-Institut de Ciencies Fotoniques, Mediterranean Technology Park, E-08860 Castelldefels (Barcelona) (Spain); Research Institute for Solid State Physics and Optics, P.O. Box 49, H-1525 Budapest (Hungary); Zamora, A. [ICFO-Institut de Ciencies Fotoniques, Mediterranean Technology Park, E-08860 Castelldefels (Barcelona) (Spain); Lewenstein, M. [ICFO-Institut de Ciencies Fotoniques, Mediterranean Technology Park, E-08860 Castelldefels (Barcelona) (Spain); ICREA-Institucio Catalana de Recerca i Estudis Avancats, Lluis Companys 23, E-08010 Barcelona (Spain)

    2011-07-15

    We propose an experimentally feasible setup with ultracold alkaline-earth-metal atoms to simulate the dynamics of U(1) lattice gauge theories in 2 + 1 dimensions with a Chern-Simons term. To this end we consider the ground-state properties of spin-5/2 alkaline-earth-metal fermions in a honeycomb lattice. We use the Gutzwiller projected variational approach in the strongly repulsive regime in the case of filling 1/6. The ground state of the system is a chiral spin-liquid state with 2{pi}/3 flux per plaquette, which violates time-reversal invariance. We demonstrate that due to the breaking of time-reversal symmetry the system exhibits quantum Hall effect and chiral edge states. We relate the experimentally accessible spin fluctuations to the emerging gauge-field dynamics. We discuss also properties of the lowest energy competing orders.

  10. Detection of zero anisotropy at 5.2 AU during the November 1998 solar particle event: Ulysses Anisotropy Telescopes observations

    Directory of Open Access Journals (Sweden)

    S. Dalla

    Full Text Available For the first time during the mission, the Anisotropy Telescopes instrument on board the Ulysses spacecraft measured constant zero anisotropy of protons in the 1.3-2.2 MeV energy range, for a period lasting more than three days. This measurement was made during the energetic particle event taking place at Ulysses between 25 November and 15 December 1998, an event characterised by constant high proton fluxes within a region delimited by two interplanetary forward shocks, at a distance of 5.2 AU from the Sun and heliographic latitude of 17°S. We present the ATs results for this event and discuss their possible interpretation and their relevance to the issue of intercalibration of the two telescopes.

    Key words: Interplanetary physics (energetic particles - Solar physics, astrophysics and astronomy (energetic particles - Space plasma physics (instruments and techniques

  11. Magic wavelengths for the 7s1/2-6d3/2,5/2 transitions in Ra+

    Science.gov (United States)

    Wu, Xiao-Mei; Li, Cheng-Bin; Tang, Yong-Bo; Shi, Ting-Yun

    2016-09-01

    The dynamic polarizabilities of the 7s and 6d states of Ra+ are calculated using a relativistic core polarization potential method. The magic wavelengths of the 7s1/2-6d3/2,5/2 transitions are identified. Comparing to the common radio-frequency (RF) ion traps, using the laser field at the magic wavelength to trap the ion could suppress the frequency uncertainty caused by the micromotion of the ion, and would not affect the transition frequency measurements. The heating rates of the ion and the powers of the laser for the ion trapping are estimated, which would benefit the possible precision measurements based on all-optical trapped Ra+. Project supported by the National Basic Research Program of China (Grant No. 2012CB821305) and the National Natural Science Foundation of China (Grant Nos. 91336211 and 11504094).

  12. Phase transformation of PZST-86/14-5-2Nb ceramic under quasi-static loading conditions.

    Energy Technology Data Exchange (ETDEWEB)

    Broome, Scott Thomas; Scofield, Timothy W.; Montgomery, Stephen Tedford; Bauer, Stephen J.; Hofer, John H.

    2010-02-01

    Specimens of poled and unpoled PZST ceramic were tested under hydrostatic loading conditions at temperatures of -55, 25, and 75 C. The objective of this experimental study was to obtain the electro-mechanical properties of the ceramic and the criteria of FE (Ferroelectric) to AFE (Antiferroelectric) phase transformations of the PZST ceramic to aid grain-scale modeling efforts in developing and testing realistic response models for use in simulation codes. As seen in previous studies, the poled ceramic from PZST undergoes anisotropic deformation during the transition from a FE to an AFE phase at -55 C. Warmer temperature tests exhibit anisotropic deformation in both the FE and AFE phase. The phase transformation is permanent at -55 C for all ceramics tests, whereas the transformation can be completely reversed at 25 and 75 C. The change in the phase transformation pressures at different temperatures were practically identical for both unpoled and poled PZST specimens. Bulk modulus for both poled and unpoled material was lowest in the FE phase, intermediate in the transition phase, and highest in the AFE phase. Additionally, bulk modulus varies with temperature in that PZST is stiffer as temperature decreases. Results from one poled-biased test for PZST and four poled-biased tests from PNZT 95/5-2Nb are presented. A bias of 1kV did not show noticeable differences in phase transformation pressure for the PZST material. However, with PNZT 95/5-2Nb phase transformation pressure increased with increasing voltage bias up to 4.5kV.

  13. (Z-5-(2,4-Dihydroxybenzylidenethiazolidine-2,4-dione Prevents UVB-Induced Melanogenesis and Wrinkle Formation through Suppressing Oxidative Stress in HRM-2 Hairless Mice

    Directory of Open Access Journals (Sweden)

    Bonggi Lee

    2016-01-01

    Full Text Available Background. Uncontrolled melanogenesis and wrinkle formation are an indication of photoaging. Our previous studies demonstrated that (Z-5-(2,4-dihydroxybenzylidenethiazolidine-2,4-dione (MHY498 inhibited tyrosinase activity and melanogenesis in vitro. Objective. To examine in vivo effects of MHY498 as an antiaging compound on UVB-induced melanogenesis and wrinkle formation, we topically applied MHY498 on dorsal skin of HRM-2 hairless mice. Methods. Using histological analysis, we evaluated effects of MHY498 on melanogenesis and wrinkle formation after UVB exposure. In addition, related molecular signaling pathways were examined using western blotting, fluorometric assay, and enzyme-linked immunosorbent assay. Results. MHY498 suppressed UVB-induced melanogenesis by inhibiting phosphorylation of CREB and translocation of MITF protein into the nucleus, which are key factors for tyrosinase expression. Consistently, tyrosinase protein levels were notably reduced in the dorsal skin of the hairless mice by MHY498 treatment. Furthermore, MHY498 inhibited UVB-induced wrinkle formation and collagen fiber destruction by increasing type 1 procollagen concentration and decreasing protein expression levels of MMPs, which play an essential role in collagen fiber degradation. As a mechanism, MHY498 notably ameliorated UVB-induced oxidative stress and NF-κB activation in the dermal skin of the hairless mice. Conclusion. Our study suggests that MHY498 can be used as a therapeutic or cosmetic agent for preventing uncontrolled melanogenesis and wrinkle formation.

  14. Fatal intoxication with 3-methyl-N-methylcathinone (3-MMC) and 5-(2-aminopropyl)benzofuran (5-APB).

    Science.gov (United States)

    Adamowicz, Piotr; Zuba, Dariusz; Byrska, Bogumiła

    2014-12-01

    The emergence of a large number of new psychoactive substances (NPSs) in recent years poses a serious problem to clinical and forensic toxicologists. Here we report a patient who administrated ca. 500mg of 3-MMC (3-methyl-N-methylcathinone) and 400mg of 5-APB (5-(2-aminopropyl)benzofuran) in combination with 80g of ethyl alcohol. The clinical manifestations included agitation, seizures, hypertension, tachycardia, hyperthermia and bradycardia. The patient did not recover and died around 4h after the use of drugs. The cause of death was acute cardiovascular collapse that occurred following mixed intoxication with NPSs and alcohol. Toxicological analysis of post-mortem blood revealed 3-MMC and 5-APB in concentrations of 1.6μg/mL and 5.6μg/mL, respectively. Moreover, the serum alcohol concentration was 1.4g/L in ante-mortem sample collected 1h after admission to the hospital. This is the first report on blood concentration of 3-MMC and 5-APB in fatal intoxication. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

  15. Co-oligomers Based on 2-Methoxy, 5-(2’-ethylhexyloxy phenylene and Thienylenevinylene for Organic Solar Cells

    Directory of Open Access Journals (Sweden)

    A. El Alamy

    2016-07-01

    Full Text Available Thanks to their optoelectronic properties and specific applications such as organic solar cells, the research on the lower band gap of organic p-conjugated materials encompassing both polymers and oligomers have been widely studied over the last years. The control of the band gap of these materials is a research issue of ongoing interest. In this study, theoretical study using the DFT method on four oligomers based on 2-methoxy, 5-(2’-ethylhexyloxy phenylene and thienylenevinylene is reported. The theoretical ground-state geometry and electronic structure of the studied molecules were obtained by the DFT method at the B3LYP level with a 6–31G (d basis set. Theoretical knowledge of the highest occupied molecular orbital (HOMO, the lowest unoccupied molecular orbital (LUMO energy levels the gap energy (Eg and the open-circuit voltage (Voc of the studied compounds are calculated and discussed. The results of this work suggest these materials as a good candidate for organic solar cells.  DOI: http://dx.doi.org/10.17807/orbital.v8i3.800

  16. A theoretical study on 2-chloro-5-(2-hydroxyethyl-4-methoxy-6-methylpyrimidine by DFT/ab initio calculations

    Directory of Open Access Journals (Sweden)

    Gümüs Hacer Pir

    2015-06-01

    Full Text Available Quantum chemical calculations have been performed to study the molecular geometry, 1H and 13C NMR chemical shifts, conformational, natural bond orbital (NBO and nonlinear optical (NLO properties of the 2-chloro-5-(2-hydroxyethyl-4- methoxy-6-methylpyrimidine molecule in the ground state using DFT and HF methods with 6-311++G(d,p basis set. The optimized geometric parameters and 1H and 13C NMR chemical shifts have been compared with the experimental values of the title molecule. The results of the calculations show excellent agreement between the experimental and calculated frequencies at B3LYP/6-311++G(d,p level. In order to provide a full understanding of the properties of the title molecule in the context of molecular orbital picture, the highest occupied molecular energy level (EHOMO, the lowest unoccupied molecular energy level (ELUMO, the energy difference (DE between EHOMO and ELUMO, electronegativity (χ, hardness (η and softness (S have been calculated using B3LYP/6-311++G(d,p and HF/6-311++G(d,p levels. The calculated HOMO and LUMO energies show that the charge transfer occurs within the title molecule.

  17. Satellite thermal IR and atmospheric radon anomalies associated with the Haripur earthquake (Oct 2010; Mw 5.2), Pakistan

    Science.gov (United States)

    Awais, Muhammad; Barkat, Adnan; Ali, Aamir; Rehman, Khaista; Ali Zafar, Waqar; Iqbal, Talat

    2017-12-01

    The recent scientific progress in the context of earthquake forecasting reveals some key physical processes related to seismic activity. The lithosphere-atmosphere-ionosphere coupling model provides a comprehensive mechanism to understand the underlying key physical processes. In this study, a precursory analysis was conducted for the shallow, moderate-magnitude Haripur earthquake (Oct 2010; Mw 5.2) bounded by two major water reservoirs, highlighting its significance. This precursory analysis was performed using the land surface temperature (LST) extracted from satellite (MODIS) thermal infrared data and atmospheric radon concentration recorded at Islamabad and Murree stations using radon monitors. A significant change in LST (4-8 °C) was observed in the epicentral region 6 days prior to this event. In addition, a comparison was made between daily and five-year-averaged LST that further supports our results. The radon concentration also showed anomalous behavior 3-4 days prior to this particular event with crucial meteorological indicators in the safe limit. This abnormal behavior of both precursors prior to this event proposes a possible correlation with the local seismic activity. Moreover, the higher amplitude of radon anomaly at the nearest station (Islamabad) is also validating its local cause. The results presented in this study are very encouraging and stimulate the idea of earthquake forecasting using multi-precursory approach.

  18. The discovery of six Ly{alpha} emitters near a radio galaxy at z {approx} 5.2

    Energy Technology Data Exchange (ETDEWEB)

    Venemans, B P; Rottgering, H A; Overzier, R A; Miley, G K; De Breuck, C; Kurk, J D; van Breugel, W; Carilli, C L; Ford, H; Heckman, T; McCarthy, P; Pentericci, L

    2004-09-15

    The authors present the results of narrow-band and broad-band imaging with the Very Large Telescope of the field surrounding the radio galaxy TN J0924-2201 at z = 5.2. 14 candidate Ly{alpha} emitters with an observed equivalent width of at least 124 {angstrom} were detected. Spectroscopy of 8 of these objects revealed 6 having redshifts similar to that of the radio galaxy. The density of emitters near the radio galaxy is a factor 3-4 higher than in the field, and comparable to the density of Ly{alpha} emitters in the protocluster 1338-1942 at z = 4.1. The Ly{alpha} emitters near TN J0924-2201 could therefore be part of a structure that will evolve into a 10{sup 15} M{sub {circle_dot}} cluster. These observations confirm that substantial clustering of Ly{alpha} emitters occur at z > 5 and strengthen the idea that radio galaxies in the early Universe pinpoint regions of high density.

  19. Molecular weight dependent charge carrier mobility in poly(3,3' '-dioctyl-2,2':5',2' '-terthiophene).

    Science.gov (United States)

    Verilhac, Jean-Marie; Pokrop, Rafal; LeBlevennec, Gilles; Kulszewicz-Bajer, Irena; Buga, Katarzyna; Zagorska, Malgorzata; Sadki, Said; Pron, Adam

    2006-07-13

    Poly(3,3' '-dioctyl-2,2':5',2' '-terthiophene), a polymer recently used for the fabrication of organic field effect transistors, has been fractionated into five fractions distinctly differing in their molecular weights (Mn), with the goal of determining the influence of the degree of polymerization (DPn) on its principal physicochemical parameters. It has been demonstrated that within the Mn range studied (from 1.5 kDa to 10.5 kDa by SEC), corresponding to DPn from 10 to 38, the polymer band gap steadily decreases with growing molecular weight, which is clearly manifested by an increasing bathochromic shift of the band originating from the pi-pi* transition. The same trend is observed for the HOMO level, determined from the onset of the p-doping in cyclic voltammetry, which shifts from -5.10 eV to -4.90 eV for the lowest and the highest molecular weight fractions, respectively. The most pronounced influence of DPn has been found for the charge carriers' mobility-one of the most important parameters of field effect transistors (FETs) fabricated from this polymer. A fourfold increase in DPn results in an increase of the carriers' mobility by more than 3 orders of magnitude. Comparison of these results with those obtained for fractionated regioregular poly(3-hexylthiophene) shows a strikingly similar behavior of both polymers with respect to the molecular weight.

  20. A SPITZER MIPS STUDY OF 2.5-2.0 M{sub Sun} STARS IN SCORPIUS-CENTAURUS

    Energy Technology Data Exchange (ETDEWEB)

    Chen, Christine H.; Bitner, Martin [Space Telescope Science Institute, 3700 San Martin Drive, Baltimore, MD 21218 (United States); Pecaut, Mark; Mamajek, Eric E. [Department of Physics and Astronomy, University of Rochester, Rochester, NY 14627 (United States); Su, Kate Y. L., E-mail: cchen@stsci.edu [Steward Observatory, University of Arizona, 933 North Cherry Avenue, Tucson, AZ 85721 (United States)

    2012-09-10

    We have obtained Spitzer Space Telescope Multiband Imaging Photometer for Spitzer (MIPS) 24 {mu}m and 70 {mu}m observations of 215 nearby, Hipparcos B- and A-type common proper-motion single and binary systems in the nearest OB association, Scorpius-Centaurus. Combining our MIPS observations with those of other ScoCen stars in the literature, we estimate 24 {mu}m B+A-type disk fractions of 17/67 (25{sup +6}{sub -5}%), 36/131 (27{sup +4}{sub -4}%), and 23/95 (24{sup +5}{sub -4}%) for Upper Scorpius ({approx}11 Myr), Upper Centaurus Lupus ({approx}15 Myr), and Lower Centaurus Crux ({approx}17 Myr), respectively, somewhat smaller disk fractions than previously obtained for F- and G-type members. We confirm previous IRAS excess detections and present new discoveries of 51 protoplanetary and debris disk systems, with fractional infrared luminosities ranging from L{sub IR}/L{sub *} = 10{sup -6} to 10{sup -2} and grain temperatures ranging from T{sub gr} = 40 to 300 K. In addition, we confirm that the 24 {mu}m and 70 {mu}m excesses (or fractional infrared luminosities) around B+A-type stars are smaller than those measured toward F+G-type stars and hypothesize that the observed disk property dependence on stellar mass may be the result of a higher stellar companion fraction around B- and A-type stars at 10-200 AU. Finally, we note that the majority of the ScoCen 24 {mu}m excess sources also possess 12 {mu}m excess, indicating that Earth-like planets may be forming via collisions in the terrestrial planet zone at {approx}10-100 Myr.

  1. Effectiveness of the cross-compliance standard 5.2 'buffer strips' on protecting freshwater against diffuse nitrogen pollution

    Directory of Open Access Journals (Sweden)

    Bruna Gumiero

    2016-02-01

    Full Text Available Sette Fasce Tampone, realizzate secondo le indicazioni tecniche contenute nello standard di condizionalità 5.2, in diversi ambiti e contesti climatici, sono state monitorate per un periodo biennale, al fine di quantificare la loro efficienza nella rimozione di azoto inorganico disciolto. Tale azoto è costituito per lo più da molecole di azoto nitrico che vengono veicolate principalmente tramite deflussi sub-superficiali da zone soggette a diverse pratiche colturali verso i corpi idrici superficiali adiacenti. Ad eccezione di due casi: i siti di Lodi e Metaponto, in tutti i sistemi monitorati è stata confermata la presenza di deflussi trasversali ai sistemi tampone, permanenti o temporanei, in grado di veicolare inquinanti e con portate variabili fra 919 e 8.590 m3/anno per 100 m lineari di FT. Le differenze di portata sono imputabili principalmente alla diversa superficie dei bacini agricoli afferenti ai sistemi tampone, che nei casi analizzati occupano superfici variabili fra il 3,6 ed il 33,3% del bacino agricolo. Sulla base dei bilanci di massa è emerso che dai campi coltivati giungono ai sistemi tampone percentuali variabili fra l’1,6 ed il 29,4% dell’azoto inorganico applicato. Ad eccezione dei sistemi in cui i maggiori deflussi non hanno alcuna interazione con la rizosfera (deflussi profondi oppure non attraversano la Fascia Tampone, in tutti gli altri siti si registra un effetto di riduzione dell’azoto fra entrata ed uscita, con percentuali variabili fra il 33 ed il 62 %. Percentuali di abbattimento non elevate sono giustificate dallo scarso grado di maturazione dei siti monitorati, in molti casi recentemente convertiti a Fascia Tampone. Ancora una volta si conferma l’estrema eterogeneità delle risposte di questi sistemi ed il ruolo prioritario delle forzanti idrologiche nel determinarne l’efficacia.Seven buffer strips (BS adjacent to fresh water bodies, realized according to the technical data contained in the standard 5.2

  2. Semivolatile POA and parameterized total combustion SOA in CMAQv5.2: impacts on source strength and partitioning

    Directory of Open Access Journals (Sweden)

    B. N. Murphy

    2017-09-01

    Full Text Available Mounting evidence from field and laboratory observations coupled with atmospheric model analyses shows that primary combustion emissions of organic compounds dynamically partition between the vapor and particulate phases, especially as near-source emissions dilute and cool to ambient conditions. The most recent version of the Community Multiscale Air Quality model version 5.2 (CMAQv5.2 accounts for the semivolatile partitioning and gas-phase aging of these primary organic aerosol (POA compounds consistent with experimentally derived parameterizations. We also include a new surrogate species, potential secondary organic aerosol from combustion emissions (pcSOA, which provides a representation of the secondary organic aerosol (SOA from anthropogenic combustion sources that could be missing from current chemical transport model predictions. The reasons for this missing mass likely include the following: (1 unspeciated semivolatile and intermediate volatility organic compound (SVOC and IVOC, respectively emissions missing from current inventories, (2 multigenerational aging of organic vapor products from known SOA precursors (e.g., toluene, alkanes, (3 underestimation of SOA yields due to vapor wall losses in smog chamber experiments, and (4 reversible organic compounds–water interactions and/or aqueous-phase processing of known organic vapor emissions. CMAQ predicts the spatially averaged contribution of pcSOA to OA surface concentrations in the continental United States to be 38.6 and 23.6 % in the 2011 winter and summer, respectively. Whereas many past modeling studies focused on a particular measurement campaign, season, location, or model configuration, we endeavor to evaluate the model and important uncertain parameters with a comprehensive set of United States-based model runs using multiple horizontal scales (4 and 12 km, gas-phase chemical mechanisms, and seasons and years. The model with representation of semivolatile POA

  3. Stimulation of the faecal excretion of 2,4,5,2',4',5'-hexachlorobiphenyl in rats by squalane.

    Science.gov (United States)

    Richter, E; Schäfer, S G; Fichtl, B

    1983-06-01

    Faecal excretion of 2,4,5,2',4',5'-hexachlorobiphenyl (6-CB) was followed for 19 weeks in rats fed a control diet, or a squalane-supplemented diet, for up to 17 weeks. In 3 d after a single oral dose of 8 mg/kg of 6-CB, 20% dose was excreted in faeces as unchanged 6-CB, which probably represents that not-absorbed. From day 4 to 133 only an additional 2-4% dose was excreted in faeces by control animals. Addition of 8% squalane to the diet 2, 6 and 15 weeks after dosing resulted in a five-fold increase of daily 6-CB excretion in faeces independent of the time of beginning the treatment. Total excretion of 6-CB in faeces from day 4 to 133 was 3.6, 6-7 and 9.3% dose after 4, 13 and 17 weeks of squalane treatment, respectively. No adverse effects of long-term squalane treatment on body-weight gain, feed efficiency and organ weights were observed. Plasma cholesterol and triglycerides were significantly lowered. Independent of the duration of treatment, the livers of rats fed the squalane-supplemented diet contained 40-50 micrograms/g squalane. Within the limits of detection no squalane could be found in lungs, kidneys, abdominal fat, spleen and blood. It is concluded that 6-CB elimination can be enhanced by oral treatment with squalane even a long time after uptake of the poison. As there was no alteration in the tissue distribution of 6-CB, the 6-CB excreted after squalane treatment probably originates from all tissues.

  4. VizieR Online Data Catalog: The Million Quasars (Milliquas) catalog (V5.2) (Flesch, 2017)

    Science.gov (United States)

    Flesch, E. W.

    2017-08-01

    This is a compendium of 607,208 type-I QSOs and AGN, largely complete from the literature to 5-August-2017, including the release of SDSS-DR14. Also included are ~1.35M high-confidence (80%+ likelihood) quasar candidates from the NBCKDE, NBCKDE-v3, XDQSO, AllWISE and Peters photometric quasar catalogs (citations in Note 7 below) and from all-sky radio/X-ray associated objects which are calculated here. Type-II and Bl Lac objects are also included, bringing the total count to 1,998,464. Changes from version 5.1 are: (1) SDSS-DR14 and SDSS-DR14Q have been added, using the processing rules from the Half Million Quasars catalog (HMQ: Flesch 2015PASA...32...10F). (2) WISE quasar candidates have been added from Secrest et al, 2015, Cat. J/ApJS/221/12; these are ~430K candidates over the whole sky for which 2-color optical objects were found within a 2-arcsec radius. They have been processed into pQSOs from calibration against the SDSS-DR12Q multi-class superset, and photometric redshifts obtained using the four-color based method from the HMQ appendix 2. The four colors used were B-R, R-W1, W1-W2 & W2-W3. (3) Type-II narrow emission-line galaxies, (NELGs, class='N') are added as the luminosity class corresponding to the type-I AGN galaxies. High-luminosity type-II NLAGN (class='K') correspond to the type-I quasars. The NLAGN/NELG divider is the same luminosity/psf function which separates QSOs from AGNs. Type-II NELGs include unquantified contamination by LINERs and probably a few starbursts which eluded removal, so it serves as a catch-all category presented for completeness, rather than as a strict type-II class. (4) Small publications to 5 August 2017 have been added. (5) Positional fixes (of about 2 arcsec) have been applied to ~150 objects. Low-confidence or questionable objects (so deemed by their researchers) are not included in Milliquas. Additional quality cuts can be applied as detailed in Flesch 2015PASA...32...10F). Multiple lensed images are excluded and

  5. AVHRR Pathfinder Version 5.2 Level 3 Collated (L3C) Global 4km Sea Surface Temperature for 1981-2012

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The AVHRR Pathfinder Version 5.2 Sea Surface Temperature data set (PFV52) is a collection of global, twice-daily 4km sea surface temperature data produced in a...

  6. Enclosure from DOE letter dated 7/20/07 - Table 5-2, Isotopic Compositions of Rocky Flats Plutonium and Uranium

    Science.gov (United States)

    This enclosure from a DOE letter to EPA regarding a waste container disposed at the WIPP from the Advanced Mixed Waste Treatment Project includes Table 5-2, Isotopic Compositions of Rocky Flats Plutonium and Uranium.

  7. Synthesis of a Library of 1,5,2-Dithiazepine 1,1-Dioxides. Part 1: A One-Pot Sulfonylation/Thia-Michael Protocol

    OpenAIRE

    Zang, Qin; Zhou, Aihua; Javed, Salim; Maity, Pradip K.; Knudtson, Chris A.; Bi, Danse; Hastings, Jared J.; Basha, Fatima Z.; Hanson, Paul R.

    2012-01-01

    A novel one-pot sulfonylation/intramolecular thia-Michael protocol is reported for the synthesis of 1,5,2-dithiazepine 1,1-dioxides. Sulfonylation between cysteine ethyl ester/cysteamine and 2-chloroethanesulfonyl chloride, followed by in situ intramolecular thia-Michael addition, was achieved and afforded the titled 1,5,2-dithiazepine-1,1-dioxide scaffolds. Diversification was demonstrated for future library synthesis.

  8. Climate change alters low flows in Europe under global warming of 1.5, 2, and 3 °C

    Science.gov (United States)

    Marx, Andreas; Kumar, Rohini; Thober, Stephan; Rakovec, Oldrich; Wanders, Niko; Zink, Matthias; Wood, Eric F.; Pan, Ming; Sheffield, Justin; Samaniego, Luis

    2018-02-01

    There is growing evidence that climate change will alter water availability in Europe. Here, we investigate how hydrological low flows are affected under different levels of future global warming (i.e. 1.5, 2, and 3 K with respect to the pre-industrial period) in rivers with a contributing area of more than 1000 km2. The analysis is based on a multi-model ensemble of 45 hydrological simulations based on three representative concentration pathways (RCP2.6, RCP6.0, RCP8.5), five Coupled Model Intercomparison Project Phase 5 (CMIP5) general circulation models (GCMs: GFDL-ESM2M, HadGEM2-ES, IPSL-CM5A-LR, MIROC-ESM-CHEM, NorESM1-M) and three state-of-the-art hydrological models (HMs: mHM, Noah-MP, and PCR-GLOBWB). High-resolution model results are available at a spatial resolution of 5 km across the pan-European domain at a daily temporal resolution. Low river flow is described as the percentile of daily streamflow that is exceeded 90 % of the time. It is determined separately for each GCM/HM combination and warming scenario. The results show that the low-flow change signal amplifies with increasing warming levels. Low flows decrease in the Mediterranean region, while they increase in the Alpine and Northern regions. In the Mediterranean, the level of warming amplifies the signal from -12 % under 1.5 K, compared to the baseline period 1971-2000, to -35 % under global warming of 3 K, largely due to the projected decreases in annual precipitation. In contrast, the signal is amplified from +22 (1.5 K) to +45 % (3 K) in the Alpine region due to changes in snow accumulation. The changes in low flows are significant for regions with relatively large change signals and under higher levels of warming. However, it is not possible to distinguish climate-induced differences in low flows between 1.5 and 2 K warming because of (1) the large inter-annual variability which prevents distinguishing statistical estimates of period-averaged changes for a given GCM/HM combination, and (2

  9. Semivolatile POA and parameterized total combustion SOA in CMAQv5.2: impacts on source strength and partitioning

    Energy Technology Data Exchange (ETDEWEB)

    Murphy, Benjamin N.; Woody, Matthew C.; Jimenez, J. L.; Carlton, A. G.; Hayes, Patrick; Liu, Shang; Ng, Nga L.; Russell, Lynn M.; Setyan, Ari; Xu, Lu; Young, Jeff; Zaveri, Rahul A.; Zhang, Qi; Pye, Havala O.

    2017-09-20

    Mounting evidence from field and laboratory observations coupled with atmospheric model analyses show that primary combustion emissions of organic compounds dynamically partition between the vapor and particulate phases, espe-cially as near-source emissions dilute and cool to ambient conditions. The most recent version of the Community Multiscale Air Quality (CMAQ) Model v5.2 accounts for the semivolatile partitioning and gas-phase aging of these primary organic aerosol (POA) compounds consistent with experimentally derived parameterizations. We also include a new surrogate species, potential secondary organic aerosol from combustion emissions (pcSOA), which provides a representation of the SOA from an-thropogenic combustion sources that could be missing from current chemical transport model predictions. The reasons for this missing mass likely include the following: 1) unspeciated semivolatile and intermediate volatility organic compound (SVOC and IVOC, respectively) emissions missing from current inventories, 2) multigenerational aging of organic vapor products from known SOA precursors (e.g. toluene, alkanes, etc), 3) underestimation of SOA yields due to vapor wall losses in smog chamber experiments, and 4) reversible organic-water interactions and/or aqueous-phase processing of known organic vapor emissions. CMAQ predicts the spatially-averaged contribution of pcSOA to OA surface concentrations in the continental United States to be 38.6% and 23.6% in the 2011 winter and summer, respectively. Whereas many past modeling studies focused on a particular measurement campaign, season, location, or model configuration, we endeavor to evaluate the model and important uncertain parameters with a comprehensive set of United States-based model runs using multiple horizontal scales (4 km and 12 km), gas-phase chemical mechanisms, seasons and years. The model with representation of semivolatile POA improves predictions of hourly OA observations over the traditional

  10. FY 2009 Annual Report of Joule Software Metric SC GG 3.1/2.5.2, Improve Computational Science Capabilities

    Energy Technology Data Exchange (ETDEWEB)

    Kothe, Douglas B [ORNL; Roche, Kenneth J [ORNL; Kendall, Ricky A [ORNL

    2010-01-01

    The Joule Software Metric for Computational Effectiveness is established by Public Authorizations PL 95-91, Department of Energy Organization Act, and PL 103-62, Government Performance and Results Act. The U.S. Office of Management and Budget (OMB) oversees the preparation and administration of the President s budget; evaluates the effectiveness of agency programs, policies, and procedures; assesses competing funding demands across agencies; and sets the funding priorities for the federal government. The OMB has the power of audit and exercises this right annually for each federal agency. According to the Government Performance and Results Act of 1993 (GPRA), federal agencies are required to develop three planning and performance documents: 1.Strategic Plan: a broad, 3 year outlook; 2.Annual Performance Plan: a focused, 1 year outlook of annual goals and objectives that is reflected in the annual budget request (What results can the agency deliver as part of its public funding?); and 3.Performance and Accountability Report: an annual report that details the previous fiscal year performance (What results did the agency produce in return for its public funding?). OMB uses its Performance Assessment Rating Tool (PART) to perform evaluations. PART has seven worksheets for seven types of agency functions. The function of Research and Development (R&D) programs is included. R&D programs are assessed on the following criteria: Does the R&D program perform a clear role? Has the program set valid long term and annual goals? Is the program well managed? Is the program achieving the results set forth in its GPRA documents? In Fiscal Year (FY) 2003, the Department of Energy Office of Science (DOE SC-1) worked directly with OMB to come to a consensus on an appropriate set of performance measures consistent with PART requirements. The scientific performance expectations of these requirements reach the scope of work conducted at the DOE national laboratories. The Joule system

  11. Type inference for correspondence types

    DEFF Research Database (Denmark)

    Hüttel, Hans; Gordon, Andy; Hansen, Rene Rydhof

    2009-01-01

    We present a correspondence type/effect system for authenticity in a π-calculus with polarized channels, dependent pair types and effect terms and show how one may, given a process P and an a priori type environment E, generate constraints that are formulae in the Alternating Least Fixed......-Point (ALFP) logic. We then show how a reasonable model of the generated constraints yields a type/effect assignment such that P becomes well-typed with respect to E if and only if this is possible. The formulae generated satisfy a finite model property; a system of constraints is satisfiable if and only...... if it has a finite model. As a consequence, we obtain the result that type/effect inference in our system is polynomial-time decidable....

  12. Updating cover type maps using sequential indicator simulation

    NARCIS (Netherlands)

    Magnussen, S.; Bruin, de S.

    2003-01-01

    Maximum posterior probability (MAP) maps of forest inventory (FI) cover type classes were produced from a maximum likelihood (ML) classified TM image and 5% (2%) systematic reference sampling of actual cover types for of nine 2 x 2 kin study sites in New Brunswick, Canada. MAP cover type maps were

  13. Blood Types

    Science.gov (United States)

    ... maternity. Learn About Blood Blood Facts and Statistics Blood Components Whole Blood and Red Blood Cells Platelets Plasma ... About Blood Blood Facts and Statistics Blood Types Blood Components What Happens to Donated Blood Blood and Diversity ...

  14. Effect of the Austempering Process on the Microstructure and Mechanical Properties of 27MnCrB5-2 Steel

    Directory of Open Access Journals (Sweden)

    Morri A.

    2017-06-01

    Full Text Available The effect of austempering parameters on the microstructure and mechanical properties of 27MnCrB5-2 steel has been investigated by means of: dilatometric, microstructural and fractographic analyses; tensile and Charpy V-notch (CVN impact tests at room temperature and a low temperature.

  15. Impacts of climate change on European hydrology at 1.5, 2 and 3 degrees mean global warming above preindustrial level

    NARCIS (Netherlands)

    Donnelly, Chantal; Greuell, Wouter; Andersson, Jafet; Gerten, Dieter; Pisacane, Giovanna; Roudier, Philippe; Ludwig, Fulco

    2017-01-01

    Impacts of climate change at 1.5, 2 and 3 °C mean global warming above preindustrial level are investigated and compared for runoff, discharge and snowpack in Europe. Ensembles of climate projections representing each of the warming levels were assembled to describe the hydro-meteorological climate

  16. QTL list: skc5.2 [PGDBj Registered plant list, Marker list, QTL list, Plant DB link and Genome analysis methods[Archive

    Lifescience Database Archive (English)

    Full Text Available QT77158 Solanum lycopersicum Solanaceae skc5.2 K+ concentrations in stems under co...ntrol conditions the K+ concentrations (mmole per Kg of dry weight) in stems 4,6 ... Chr05 31.01 14.07 ... 10.1007/s00122-008-0720-8 18251001

  17. Relationship between Adherence to Individual Goals within the 5-2-1-0 Guidelines for Obesity Prevention and Number of PACER Laps in Adolescents

    Science.gov (United States)

    Cho, Kibum; Jones, Emily; Lilly, Christa; Bulger, Sean; Braga, Luciana; Elliott, Eloise

    2017-01-01

    Background: The purpose of this study was to evaluate the relationship between adolescents' adherence to the 5-2-1-0 goals and the number of completed Progressive Cardiovascular Endurance Run (PACER) laps. Methods: Participants included 1792 students aged 10 to 16 years who were randomly selected across 9 data collection periods between 2012 and…

  18. Looking for ΔI=5/2 amplitude components in B→ππ and B→ρρ experiments

    Science.gov (United States)

    Botella, F. J.; London, David; Silva, João P.

    2006-04-01

    We discuss how experiments measuring B→ππ and B→ρρ may be used to search for a ΔI=5/2 amplitude component. This component could be the explanation for a recent (albeit very tentative) hint from B(B¯)→ρρ decays that the isospin triangles do not close.

  19. Wayfinding the Live 5-2-1-0 Initiative-At the Intersection between Systems Thinking and Community-Based Childhood Obesity Prevention.

    Science.gov (United States)

    Amed, Shazhan; Shea, Stephanie; Pinkney, Susan; Wharf Higgins, Joan; Naylor, Patti-Jean

    2016-06-21

    Childhood obesity is complex and requires a 'systems approach' that collectively engages across multiple community settings. Sustainable Childhood Obesity Prevention through Community Engagement (SCOPE) has implemented Live 5-2-1-0-a multi-sector, multi-component childhood obesity prevention initiative informed by systems thinking and participatory research via an innovative knowledge translation (KT) model (RE-FRAME). This paper describes the protocol for implementing and evaluating RE-FRAME in two 'existing' (>2 years of implementation) and two 'new' Live 5-2-1-0 communities to understand how to facilitate and sustain systems/community-level change. In this mixed-methods study, RE-FRAME was implemented via online resources, webinars, a backbone organization (SCOPE) coordinating the initiative, and a linking system supporting KT. Qualitative and quantitative data were collected using surveys and stakeholder interviews, analyzed using thematic analysis and descriptive statistics, respectively. Existing communities described the consistency of Live 5-2-1-0 and extensive local partnerships/champions as catalysts for synergistic community-wide action; new communities felt that the simplicity of the message combined with the transfer of experiential learning would inform their own strategies and policies/programs to broadly disseminate Live 5-2-1-0. RE-FRAME effectively guided the refinement of the initiative and provided a framework upon which evaluation results described how to implement a community-based systems approach to childhood obesity prevention.

  20. Study of the deformation-driving νd5/2 orbital in 6728Ni39 using one-neutron transfer reactions

    Directory of Open Access Journals (Sweden)

    J. Diriken

    2014-09-01

    Full Text Available The νg9/2,d5/2,s1/2 orbitals are assumed to be responsible for the swift onset of collectivity observed in the region below 68Ni. Especially the single-particle energies and strengths of these orbitals are of importance. We studied such properties in the nearby 67Ni nucleus, by performing a (d,p-experiment in inverse kinematics employing a post-accelerated radioactive ion beam (RIB at the REX-ISOLDE facility. The experiment was performed at an energy of 2.95 MeV/u using a combination of the T-REX particle detectors, the Miniball γ-detection array and a newly-developed delayed-correlation technique as to investigate μs-isomers. Angular distributions of the ground state and multiple excited states in 67Ni were obtained and compared with DWBA cross-section calculations, leading to the identification of positive-parity states with substantial νg9/2 (1007 keV and νd5/2 (2207 keV and 3277 keV single-particle strengths up to an excitation energy of 5.8 MeV. 50% of the νd5/2 single-particle strength relative to the νg9/2-orbital is concentrated in and shared between the first two observed 5/2+ levels. A comparison with extended Shell Model calculations and equivalent (3He, d studies in the region around 9040Zr50 highlights similarities for the strength of the negative-parity pf and positive-parity g9/2 state, but differences are observed for the d5/2 single-particle strength.

  1. The Prevalence of Four Types of Childhood Maltreatment in Denmark

    DEFF Research Database (Denmark)

    Christoffersen, Mogens Nygaard; Armour, Cherie; Lasgaard, Mathias

    2013-01-01

    Objectives. To estimate the prevalence of four types of childhood maltreatment in Denmark while taking into considerations how each of the types of maltreatment vary as a function of gender of child-protection status. Methods. Data were collected from a Danish national study conducted by The Danish...... abuse (5.2%), physical abuse (5.2%) and sexual abuse (3.5%). All trauma types were experienced by a greater percentage of females compared to males with the exception of physical abuse and all trauma types were experienced by a greater percentage of children given child-protection status....

  2. Preclinical pharmacokinetic characterization of 2-(4-(4-(5-(2-phenyl-5-(trifluoromethyl)oxazole-4-carboxamido)-1H-benzo[d]imidazol-2-yl)phenyl)cyclohexyl) acetic acid, a novel DGAT-1 inhibitor.

    Science.gov (United States)

    Kwak, Eun-Young; Im, So Hee; Seo, Hyewon; Cho, Woon-Ki; Lee, Ye-Lim; Woo, Jaechun; Ahn, Sunjoo; Ahn, Sung-Hoon; Kwak, Hyun Jung; Ahn, Jin Hee; Bae, Myung Ae; Song, Jin Sook

    2014-05-01

    1. A novel diacylglyceride acyltransferase-1 (DGAT-1) inhibitor, 2-(4-(4-(5-(2-phenyl-5-(trifluoromethyl) oxazole-4-carboxamido)-1H-benzo[d]imidazol-2-yl)phenyl)cyclohexyl) acetic acid (KR-69232), was synthesized for a potential therapeutic use against several metabolic disorders, such as obesity, insulin resistance, and type II diabetes, characterized by excessive triglycerides (TGs) in the blood. 2. The half-lives against phase I metabolism were measured as 75.3 ± 20.9 min and over 120 min in rat and human liver microsomes, respectively. In Caco-2 cell monolayers, extremely low permeability (99.8%). 3. With the intravenous administration of KR-69232 in rats (1, 2, and 5 mg/kg), non-linear kinetics were observed at the highest dose, with significantly higher systemic clearance, higher volume of distribution, and lower dose-normalized AUC. Following oral administration, it exhibited low bioavailability (<10%) and was absorbed slowly (T(max), 3.8-5.2 h) over the dose range. We also confirmed that considerable KR-69232 remained in the intestine at T(max), demonstrating its limited absorption into the systemic circulation.

  3. Type Tricks

    DEFF Research Database (Denmark)

    Beier, Sofie

    2017-01-01

    Type Tricks’ is about typographical rules and the underlying structure of the work process in the design of new typefaces. In that way, it is both a reference book and a user manual. In an illustrative format, it presents the different stages of type design in an easily accessible manner. Being...... their time at school. It’s the perfect reference book. The book contains a number of essential tricks that designers need to know and understand. The typographic guidelines are difficult to remember, but with this book you don’t have to remember every single one of them....

  4. Klebsiella Typing

    DEFF Research Database (Denmark)

    Hansen, D S; Skov, R; Benedí, J.V.

    2002-01-01

    OBJECTIVE: To compare pulsed-field gel electrophoresis (PFGE) typing and O:K-serotyping of Klebsiella in two different epidemiological settings. METHODS: One hundred and four bacteremia isolates without known epidemiological relation and 47 isolates from an outbreak in a neonatal intensive care...

  5. A UWOC system based on a 6 m/5.2 Gbps 680 nm vertical-cavity surface-emitting laser

    Science.gov (United States)

    Li, Chung-Yi; Tsai, Wen-Shing

    2018-02-01

    This study proves that an underwater wireless optical communication (UWOC) based on a 6 m/5.2 Gbps 68 nm vertical-cavity surface-emitting laser (VCSEL)-based system is superior to a 405 nm UWOC system. This UWOC application is the first to use a VCSEL at approximately 680 nm. The experiment also proved that a 680 nm VCSEL has the same transmission distance as that of an approximately 405 nm laser diode. The 680 nm VCSEL has a 5.2 Gbps high transmission rate and can transmit up to 6 m. Thus, the setup is the best alternative solution for high-speed UWOC applications.

  6. C-H and P-C(Ph) activation competitive processes caused by interaction with the solvate [cis-Pt(C6F5)2(thf)2].

    Science.gov (United States)

    Berenguer, Jesús R; Bernechea, María; Lalinde, Elena

    2007-06-21

    The study of the reaction between the ethylene [Pt(eta-H2C = CH2)(PPh3)2] or alkyne [Pt(eta2-HC [triple bond] CR)(PPh3)2] (R = SiMe3 1, Bu(t) 2) complexes with [cis-Pt(C6F5)2(thf)2] (thf = tetrahydrofuran) has enabled us to observe the existence of competitive processes between the activation of a P-C(Ph) bond on the PPh3 ligand, to give the binuclear derivative [cis-(C6F5)2Pt(mu-Ph)(mu-PPh2)Pt(PPh3)] 3, and the activation of a C-H bond of the unsaturated group, to give the corresponding (mu-hydride)(mu-vinyl) [cis, cis-(PPh3)2Pt(mu-H)(mu-1kappaC(alpha):eta2-CH = CH2)Pt(C6F5)2] 4 or (mu-hydride)(mu-alkynyl) [cis,cis-(PPh3)2Pt(mu-H)(mu-1kappaC(alpha):eta2-C [triple bond]CR)Pt(C6F5)2] (R = SiMe3 5, Bu(t) 6) compounds, respectively. The monitoring of these reactions by NMR spectroscopy has allowed us to detect several intermediates, and to propose a mechanism for the C-H bond activation. In addition, the structures of the (muo-hydride)(mu-alkynyl) complex 5 and the unprecedented (mu-hydride)(mu-vinyl) derivative 4 have been obtained by X-ray crystallographic analyses.

  7. Activation of SO2 with [(η(5) -C5 Me5 )2 Ln(THF)2 ] (Ln=Eu, Yb) leading to dithionite and sulfinate complexes.

    Science.gov (United States)

    Klementyeva, Svetlana V; Gamer, Michael T; Schmidt, Anna-Corina; Meyer, Karsten; Konchenko, Sergey N; Roesky, Peter W

    2014-10-13

    The reaction of decamethylytterbocene [(η(5) -C5 Me5 )2 Yb(THF)2 ] with SO2 at low temperature gave two new compounds, namely, the Yb(III) dithionite/sulfinate complex [{(η(5) -C5 Me5 )2 Yb(μ3 ,1κ(2) O(1,3) ,2κ(3) O(2,2',4) -S2 O4 )}2 {(η(5) -C5 Me5 )Yb(μ,1κO,2κO'-C5 Me5 SO2 )}2 ] (1) and the Yb(III) dithionite complex [{(η(5) -C5 Me5 )2 Yb}2 (μ,1κ(2) O(1,3) ,2κ(2) O(2,4) -S2 O4 )] (2). After extraction of 1, the mixture was heated to give the dinuclear tetrasulfinate complex [{(η(5) -C5 Me5 )Yb}2 (μ,κO,κO'-C5 Me5 SO2 )4 ] (3 a). In contrast, from the reaction of [(η(5) -C5 Me5 )2 Eu(THF)2 ] with SO2 only the tetrasulfinate complex [{(η(5) -C5 Me5 )Eu}2 (μ,κO,κO'-C5 Me5 SO2 )4 ] (3 b) was isolated. Two major reaction pathways were observed: 1) reductive coupling of two SO2 molecules to form the dithionite anion S2 O4 (2-) ; and 2) nucleophilic attack of one metallocene C5 Me5 ligand on the sulfur atom of SO2 . The compounds presented are the first dithionite and sulfinate complexes of the f-elements. © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  8. Synthesis, spectral analysis and pharmacological study of N'- substituted-2-(5-((2,4-dimethylphenoxymethyl-1,3,4-oxadiazol-2-ylthioacetohydrazides

    Directory of Open Access Journals (Sweden)

    Shahid Rasool

    Full Text Available ABSTRACT A series of molecules bearing multiple functional groups were synthesized to study their antibiotic effect against Gram-positive and Gram-negative bacteria and lipoxygenase activity as well. 2,4-Dimethylcarbolic acid (1 was refluxed with ethyl 2-bromoacetate to synthesize ethyl 2-(2,4-dimethylphenoxyacetate (2. Compound 2 was converted to the corresponding hydrazide 3, again on refluxing with hydrazine. The compound 5-((2,4-dimethylphenoxymethyl-1,3,4-oxadiazol-2-thiol (4 was synthesized by the reaction of 3 and CS2 in the presence of KOH. Compound 4 was further converted to the corresponding ester 5 and then 2-(5-((2,4-dimethylphenoxymethyl-1,3,4-oxadiazol-2-ylthioacetohydrazide (6. The final molecules N'-substituted-2-(5-((2,4-dimethylphenoxymethyl-1,3,4-oxadiazol-2-ylthioacetohydrazide, 8a-m, bearing ether, 1,3,4-oxadiazole, thioether, hydrazone and azomethine functional groups were synthesized by stirring the aryl carboxaldehydes 7a-m with 6 in methanol at room temperature. The depicted structures of all synthesized molecules were corroborated by IR, 1H-NMR and EIMS spectral data analysis. 8m and 8i showed substantial antibacterial activity and lipoxygenase inhibitory activity, respectively.

  9. Alkynyldiphenylphosphine d8 (Pt, Rh, Ir) complexes: contrasting behavior toward cis-[Pt(C6F5)2(THF)2].

    Science.gov (United States)

    Berenguer, Jesús R; Bernechea, María; Forniés, Juan; García, Ana; Lalinde, Elena; Moreno, M Teresa

    2004-12-13

    The synthesis and characterization of a series of mononuclear d(8) complexes with at least two P-coordinated alkynylphosphine ligands and their reactivity toward cis-[Pt(C(6)F(5))(2)(THF)(2)] are reported. The cationic [Pt(C(6)F(5))(PPh(2)C triple-bond CPh)(3)](CF(3)SO(3)), 1, [M(COD)(PPh(2)C triple-bond CPh)(2)](ClO(4)) (M = Rh, 2, and Ir, 3), and neutral [Pt(o-C(6)H(4)E(2))(PPh(2)C triple-bond CPh)(2)] (E = O, 6, and S, 7) complexes have been prepared, and the crystal structures of 1, 2, and 7.CH(3)COCH(3) have been determined by X-ray crystallography. The course of the reactions of the mononuclear complexes 1-3, 6, and 7 with cis-[Pt(C(6)F(5))(2)(THF)(2)] is strongly influenced by the metal and the ligands. Thus, treatment of 1 with 1 equiv of cis-[Pt(C(6)F(5))(2)(THF)(2)] gives the double inserted cationic product [Pt(C(6)F(5))(S)mu-(C(Ph)=C(PPh(2))C(PPh(2))=C(Ph)(C(6)F(5)))Pt(C(6)F(5))(PPh(2)C triple-bond CPh)](CF(3)SO(3)) (S = THF, H(2)O), 8 (S = H(2)O, X-ray), which evolves in solution to the mononuclear complex [(C(6)F(5))(PPh(2)C triple-bond CPh)Pt(C(10)H(4)-1-C(6)F(5)-4-Ph-2,3-kappaPP'(PPh(2))(2))](CF(3) SO(3)), 9 (X-ray), containing a 1-pentafluorophenyl-2,3-bis(diphenylphosphine)-4-phenylnaphthalene ligand, formed by annulation of a phenyl group and loss of the Pt(C(6)F(5)) unit. However, analogous reactions using 2 or 3 as precursors afford mixtures of complexes, from which we have characterized by X-ray crystallography the alkynylphosphine oxide compound [(C(6)F(5))(2)Pt(mu-kappaO:eta(2)-PPh(2)(O)C triple-bond CPh)](2), 10, in the reaction with the iridium complex (3). Complexes 6 and 7, which contain additional potential bridging donor atoms (O, S), react with cis-[Pt(C(6)F(5))(2)(THF)(2)] in the appropriate molar ratio (1:1 or 1:2) to give homo- bi- or trinuclear [Pt(PPh(2)C triple-bond CPh)(mu-kappaE-o-C(6)H(4)E(2))(mu-kappaP:eta(2)-PPh(2)C triple-bond CPh)Pt(C(6)F(5))(2)] (E = O, 11, and S, 12) and [(Pt(mu(3)-kappa(2)EE'-o-C(6)H(4)E(2))(mu

  10. Oxo Complexes of Tungstenocene via Oxidation of (W(Eta(5)-C5H5)2(OCH3) (CH3)) and Related Reactions: Synthesis, Structural Characterization, and Photodisproportionation of the Spin Paired d(1)-d(1) Oxo Bridged Dimer ((W(Eta(5)-C5H5)2(CH3))2(Mu-O))2(+) and Synthesis and Charaterization of the d(0) Terminal Oxo Complex (W(Eta(5)-C5H5)2(O)(CH3))(+)

    Science.gov (United States)

    1993-02-15

    of I is followed by loss of a methoxy radical and formation of an intermediate aquo complex , but conversion of this to 22+ must be more complex than a...simple condensation. One possibility is that hydrogen atom loss for the aquo complex generates a 17 electron hydroxy 2.omplex which forms 22+ by...Interim June 1 1_99 0 to June 1, 1993 IlI., ANU 5UtJIILOxo Complexes of Tungstenocene via Oxidation $-FUNOING NUMBERS of [w(n 5 -C5 H5 ) 2 (OCH 3

  11. Phase Diagram of the ν=5/2 Fractional Quantum Hall Effect: Effects of Landau-Level Mixing and Nonzero Width

    Directory of Open Access Journals (Sweden)

    Kiryl Pakrouski

    2015-04-01

    Full Text Available Interesting non-Abelian states, e.g., the Moore-Read Pfaffian and the anti-Pfaffian, offer candidate descriptions of the ν=5/2 fractional quantum Hall state. But, the significant controversy surrounding the nature of the ν=5/2 state has been hampered by the fact that the competition between these and other states is affected by small parameter changes. To study the phase diagram of the ν=5/2 state, we numerically diagonalize a comprehensive effective Hamiltonian describing the fractional quantum Hall effect of electrons under realistic conditions in GaAs semiconductors. The effective Hamiltonian takes Landau-level mixing into account to lowest order perturbatively in κ, the ratio of the Coulomb energy scale to the cyclotron gap. We also incorporate the nonzero width w of the quantum-well and subband mixing. We find the ground state in both the torus and spherical geometries as a function of κ and w. To sort out the nontrivial competition between candidate ground states, we analyze the following four criteria: its overlap with trial wave functions, the magnitude of energy gaps, the sign of the expectation value of an order parameter for particle-hole symmetry breaking, and the entanglement spectrum. We conclude that the ground state is in the universality class of the Moore-Read Pfaffian state, rather than the anti-Pfaffian, for κ<κ_{c}(w, where κ_{c}(w is a w-dependent critical value 0.6≲κ_{c}(w≲1. We observe that both Landau-level mixing and nonzero width suppress the excitation gap, but Landau-level mixing has a larger effect in this regard. Our findings have important implications for the identification of non-Abelian fractional quantum Hall states.

  12. An Optimized Synthesis, Molecular Structure and Characterization of Benzylic Derivatives of 1,2,4-Triazin-3,5(2H,4H-dione

    Directory of Open Access Journals (Sweden)

    Long-Chih Hwang

    2017-11-01

    Full Text Available 4-Benzyl-1,2,4-triazin-3,5(2H,4H-dione (3-benzyl-6-azauracil, 2, and 2,4-dibenzyl-1,2,4-triazin-3,5(2H,4H-dione (1,3-dibenzyl-6-azauracil, 3 were synthesized by the reaction of 1,2,4-triazin-3,5(2H,4H-dione (6-azauracil, 1 with benzyl bromide and potassium carbonate in dry acetone via the 18-crown-6-ether catalysis. In these reaction methods, we developed more convenient and efficient methodologies to afford compounds 2 and 3 in good yields. These compounds were characterized by 1H- and 13C-NMR, MS spectrum, IR spectroscopy and elemental analysis. The structure of 2 was verified by 2D-NMR measurements, including gHSQC and gHMBC measurements. A single-crystal X-ray diffraction experiment indicated that compound 3, with the molecular formula C17H15N3O2, crystallized from a CH3OH/CH2Cl2 diffusion solvent system in a monoclinic space group P21/c with a = 13.7844(13, b = 8.5691(8, c = 13.0527(12 Å, β = 105.961(2°, V = 1482.3(2 Å3, Z = 4, resulting in a density Dcalc of 1.314 g/cm3. The crystal structure of compound 3 is tightly stabilized by contact with five other molecules from the six short contacts formed by intermolecular C−O···H−Car, C−H···Car, and weakly π···π stacking interactions. The dihedral angle 31.90° is formed by the mean planes of the benzene rings of the N-2 and N-4 benzyl groups.

  13. Stability of the 5/2 fractional quantum Hall state in a Corbino disc sample with in-plane electric fields

    Science.gov (United States)

    Zhu, Zheyi; Wang, Pengjie; Fu, Hailong; Pfeiffer, L. N.; West, K. W.; Du, Rui-Rui; Lin, Xi

    2018-01-01

    Among the various geometries to study the fractional quantum Hall effect in two dimensional electron gas, the Corbino disc owns the advantage to probe the bulk properties directly. In this work we explore the influence of in-plane electric fields on the stability of the 5/2 fractional quantum Hall state realized in Corbino geometry. The effect of weak electric fields is investigated at ultra-low temperatures in order to compare with a theoretical proposal of enhanced Pfaffian state under weak electric fields.

  14. Tetrahedral-Atom Zincophosphate Structures. Zinc Diethyl Phosphate, Zn(02P(OC2H5)2)2x, a One-Dimensional Inorganic "Polymer"

    Science.gov (United States)

    1993-02-15

    The synthesis, structure and some properties of a new, anhydrous, zinc ethyl phosphate are described. 00 Zn(0 2P-(OC 2H5 )2)2 (ZnPOEt) crystallizes in...chains of vertex-linked zinc -oxygen andS cphosphorus-oxygen tetrahedra forming "four-rings": two of the phosphate P-O vertices are coordinated to ethyl...synthesi structure, and %&= Properts of a new, ahYdrou, zinc ethyl phosphate an cred. Za(o P-.. (OC2Hs)132 (ZaPOEt) crystallime in the monochnic $pc

  15. 25 Tb/s transmission over 5,530 km using 16QAM at 5.2 b/s/Hz spectral efficiency.

    Science.gov (United States)

    Cai, J-X; Batshon, H G; Zhang, H; Davidson, C R; Sun, Y; Mazurczyk, M; Foursa, D G; Sinkin, O; Pilipetskii, A; Mohs, G; Bergano, Neal S

    2013-01-28

    We transmit 250x100G PDM RZ-16QAM channels with 5.2 b/s/Hz spectral efficiency over 5,530 km using single-stage C-band EDFAs equalized to 40 nm. We use single parity check coded modulation and all channels are decoded with no errors after iterative decoding between a MAP decoder and an LDPC based FEC algorithm. We also observe that the optimum power spectral density is nearly independent of SE, signal baud rate or modulation format in a dispersion uncompensated system.

  16. Electrical behaviour of hydridofluorides of potassium-calcium KCaH{sub 3-x}F{sub x} with x = 1, 1.5, 2, 2.5

    Energy Technology Data Exchange (ETDEWEB)

    Bouamrane, A., E-mail: ahmed.bouamrane@insa-lyon.f [Universite de Lyon, INSA-Lyon, LGCIE, 20 Avenue Albert Einstein, 34, avenue des Arts, Coulomb2, F-69621 Villeurbanne (France); Soulie, J.-Ph. [Ilika Technologies Ltd, Southampton (United Kingdom); Sassi, Z. [Universite de Lyon, INSA-Lyon, AMPERE UMR CNRS 5005, F-69621 (France)

    2009-08-12

    This paper reports the results of the electrical conductivity measurements for KCaH{sub 3-x}F{sub x} series with (x = 1, 1.5, 2, 2.5) in the temperature range 298-503 K. The activation energy of the electrical conductivity for the studied compounds depends on hydrogen amount and Reau's criteria. Differential thermal analysis curves were measured in the same temperature range 298-503 K. Possible correspondence between preferential order given by X-ray diffraction, thermal behaviour and electrical properties are discussed.

  17. Flowrate testing of the bag filter LANCS-BOP 6CPVC-1.5-2SPVC (LANCS Industries) at 1 psig

    Energy Technology Data Exchange (ETDEWEB)

    Moore, Murray E. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Currie, Karissa Lyn [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Berg, Charlotte Katherine [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2016-09-13

    The air flowrate through a flexible HEPA grade filter (Part LANCS-BOP 6CPVC-1.5-2SPVC www.lancsindustries.com) was measured at 48 ALPM for a differential pressure drop of 1.0 psig (28 inWC, 7.0 kPa). These filters are rated by the manufacturer to have a flowrate of 3 ALPM at a differential pressure drop of 1 inWC (0.25 kPa). The Los Alamos National Laboratory Aerosol Engineering Facility used one of their test rigs (originally developed to measure the pressure drop in capsule HEPA filters) to measure the airflow through the LANCS bag filter.

  18. Carrier transport and luminescence properties of nanocomposites of poly[2-methoxy-5-(2-ethyl hexyloxy)-p-phenylene vinylene] and dehydrated nanotubes titanic acid.

    Science.gov (United States)

    Zhang, Ting; Xu, Zheng; Liu, Ran; Teng, Feng; Wang, Yongsheng; Xu, Xurong

    2007-12-01

    The carrier transport capability and luminescence efficiency of poly(2-methoxy-5-(2-ethyl hexyloxy)-p-phenylene vinylene) (MEH-PPV) films are enhanced by doping with dehydrated nanotubed titanic acid (DNTA). MEH-PPV molecules, either wrapped on the outer surface of or encapsulated into DNTA pores, have a more open, straighter conformation than undoped molecules, which induces a longer conjugated backbone and stronger interchain interactions, thereby, enhancing carrier mobility. MEH-PPV molecules within DNTA pores have higher exciton recombination efficiency owing to quantum confinement and the antenna effect.

  19. Synthesis and Antimicrobial and Antioxidant Activities of Some New 5-(2-Methyl-1H-indol-3-yl-1,3,4-oxadiazol-2-amine Derivatives

    Directory of Open Access Journals (Sweden)

    Anand R. Saundane

    2013-01-01

    Full Text Available A series of 5-(2-methyl-1H-indol-3-yl-1,3,4-oxadiazol-2-amine derivatives (3–5 were synthesized. These previously unknown compounds were characterized by spectral studies and elemental analysis. These compounds were evaluated for their antimicrobial and antioxidant activities. Among all the compounds tested 5d exhibited promising antibacterial, antifungal, radical scavenging, and ferric ions (Fe3+ reducing antioxidant power (FRAP activities, whereas the compounds 3b, 4c, and 5e exhibited good FRAP and metal chelating activities. In general compounds containing chloro and methyl substituent exhibited better antimicrobial and antioxidant activities.

  20. Response times of Cassini/INCA > 5.2 keV ENAs and Voyager ions in the heliosheath over the solar cycle

    Science.gov (United States)

    Dialynas, K.; Krimigis, S. M.; Mitchell, D. G.; Decker, R. B.; Roelof, E. C.

    2017-09-01

    Both a magnetosphere-like tail and a bubble model of the heliosphere were posited by E. N. Parker in 1961. Recently, we showed that heliosheath ions are the source of > 5.2 keV Energetic Neutral Atoms (ENA), whose images of the heliosphere exhibit a rough nose to anti-nose (tail) global symmetry that resembles a diamagnetic bubble. The comparison between energetic neutral atom (ENA) global images of the helioshphere obtained with the Ion and Neutral Camera (INCA) on board Cassini and ions measured in-situ by the Low Energy Charged Particle experiment (LECP) on board Voyager 1 and 2 (V1/V2) in overlapping energy bands over an 11-year period shows that the heliosphere responds promptly, within ∼2-3 years, to outward propagating solar wind changes in both the nose and tail directions. Here we focus on the recovery of solar cycle 24 and the response times of > 5.2 keV ENAs to show that this ∼2-3-year time delay is consistent with a “tail” of ∼80-120 AU. This preliminary rough calculation is generally consistent with lower energy ENA data (E < 6 keV, from the IBEX-Lo and IBEX-Hi) and is supported by recent modelling of the heliosphere.

  1. Types of hormone therapy

    Science.gov (United States)

    ... your doctor for regular checkups when taking HT. Alternative Names HRT- types; Estrogen replacement therapy - types; ERT- types of hormone therapy; Hormone replacement therapy - types; Menopause - types of hormone therapy; HT - types; Menopausal hormone ...

  2. Bis(2-{5-[(2-carboxyphenylsulfanylmethyl]-2,4-dimethylbenzylsulfanyl}benzoato-κ2O,O′bis(pyridine-κNiron(II

    Directory of Open Access Journals (Sweden)

    Yu-Min Xu

    2011-02-01

    Full Text Available The title compound, [Fe(C24H21O4S22(C5H5N2], has 2 symmetry. The FeII cation is located on a twofold rotation axis and is O,O′-chelated by two 2-{5-[(2-carboxyphenylsulfanylmethyl]-2,4-dimethylbenzylsulfanyl}benzoate anions and further coordinated by two pyridine ligands in a distorted octahedral geometry. In the anion, the terminal benzene rings are oriented at dihedral angles of 63.81 (14 and 84.50 (14° with respect to the central benzene ring. Intermolecular O—H...O and C—H...O hydrogen bonding is present in the crystal structure.

  3. Structural studies of advanced functional materials by synchrotron-based x-ray absorption spectroscopy: BL5.2 at SLRI, Thailand

    Science.gov (United States)

    Kidkhunthod, Pinit

    2017-09-01

    This paper highlights the use of the x-ray absorption spectroscopy (XAS) as a local structural tool unlike x-ray diffraction for selected atoms in advanced functional materials including energy storage materials, dielectric materials and thermoelectric materials. The information concerning the oxidation states and local atomic structure around probing atoms will be revealed using x-ray absorption near edge structure (XANES) and extended x-ray absorption fine structure (EXAFS). The XAS beamline: BL5.2 at the Synchrotron Light Research Institute (SLRI) (public organization), Thailand, and its characteristic including available of measured energy ranges, examples of measured spectra of Mg, S and Ti K-edge XAS are also presented. In addition, in situ XAS set up and experiment carried out at this beamline are also outlined. Invited talk at 5th Thailand International Nanotechnology Conference (Nano Thailand-2016), 27-29 November 2016, Nakhon Ratchasima, Thailand.

  4. Nuclear structure beyond the neutron drip line: The lowest energy states in 9He via their T=5/2 isobaric analogs in 9Li

    Directory of Open Access Journals (Sweden)

    E. Uberseder

    2016-03-01

    Full Text Available The level structure of the very neutron rich and unbound 9He nucleus has been the subject of significant experimental and theoretical study. Many recent works have claimed that the two lowest energy 9He states exist with spins Jπ=1/2+ and Jπ=1/2− and widths on the order of 100–200 keV. These findings cannot be reconciled with our contemporary understanding of nuclear structure. The present work is the first high-resolution study with low statistical uncertainty of the relevant excitation energy range in the 8He+n system, performed via a search for the T=5/2 isobaric analog states in 9Li populated through 8He+p elastic scattering. The present data show no indication of any narrow structures. Instead, we find evidence for a broad Jπ=1/2+ state in 9He located approximately 3 MeV above the neutron decay threshold.

  5. Enantioselective synthesis of tricyclic amino acid derivatives based on a rigid 4-azatricyclo[5.2.1.02,6]decane skeleton

    Directory of Open Access Journals (Sweden)

    Matthias Breuning

    2009-12-01

    Full Text Available An enantioselective route to four tricyclic amino acids and N-tosylamides, composed of a central norbornane framework with a 2-endo,3-endo-annelated pyrrolidine ring and a 5-endo-C1 or -C2 side chain, has been developed. A key intermediate was the chiral, N-Boc-protected ketone (1R,2S,6S,7R-4-azatricyclo[5.2.1.02,6]decan-8-one, available from inexpensive endo-carbic anhydride in five steps and 47% yield. The rigid scaffold makes these amino acid derivatives promising candidates for β-turn-inducing building blocks in peptidomimetics and for chiral auxiliaries in asymmetric organocatalysis.

  6. Inactivation of contaminated fungi and antioxidant effects of peach (Prunus persica L. Batsch cv Dangeumdo) by 0.5-2 kGy gamma irradiation

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Kyoung-Hee; Kim, Mi-Seon [Department of Food and Nutrition, Chungnam National University, Daejeon 305-764 (Korea, Republic of); Kim, Hong-Gi [Department of Applied Biology, Chungnam National University, Daejeon 305-764 (Korea, Republic of); Yook, Hong-Sun, E-mail: yhsuny@naver.co [Department of Food and Nutrition, Chungnam National University, Daejeon 305-764 (Korea, Republic of)

    2010-04-15

    The effect of gamma irradiation (0.5-2 kGy) on the physicochemical properties of peaches was investigated during a 6-day storage at 20+-3 deg. C. Gamma irradiation is able to inactivate the four pathogens, namely Botrytis cinerea, Penicillium expansum, Rhizopus stolonifer var. stolonifer and Monilinia fructicola in peaches. Hardness significantly decreased with the increment of irradiation dose level whereas soluble solid and total polyphenol contents increased with increment of irradiation dose level. 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical-scavenging activity of the irradiated peach was higher than that of control, and its activity increased with increment of irradiation dose level. These results suggest that gamma irradiation of peaches improved antioxidant activity, but dramatically affects the hardness throughout the entire storage time.

  7. Inactivation of contaminated fungi and antioxidant effects of peach ( Prunus persica L. Batsch cv Dangeumdo) by 0.5-2 kGy gamma irradiation

    Science.gov (United States)

    Kim, Kyoung-Hee; Kim, Mi-Seon; Kim, Hong-Gi; Yook, Hong-Sun

    2010-04-01

    The effect of gamma irradiation (0.5-2 kGy) on the physicochemical properties of peaches was investigated during a 6-day storage at 20±3 °C. Gamma irradiation is able to inactivate the four pathogens, namely Botrytis cinerea, Penicillium expansum, Rhizopus stolonifer var. stolonifer and Monilinia fructicola in peaches. Hardness significantly decreased with the increment of irradiation dose level whereas soluble solid and total polyphenol contents increased with increment of irradiation dose level. 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical-scavenging activity of the irradiated peach was higher than that of control, and its activity increased with increment of irradiation dose level. These results suggest that gamma irradiation of peaches improved antioxidant activity, but dramatically affects the hardness throughout the entire storage time.

  8. Memory effect in a junction-like CdS nanocomposite/conducting polymer poly[2-methoxy-5-(2-ethylhexyloxy)1,4-phenylene-vinylene] heterostructure

    Science.gov (United States)

    Mondal, S. P.; Reddy, V. S.; Das, S.; Dhar, A.; Ray, S. K.

    2008-05-01

    The operation of a nonvolatile memory device is demonstrated using junction-like CdS nanocomposites embedded in a polymer matrix. The capacitance-voltage characteristics of Al/conducting polymer poly[2-methoxy-5-(2-ethylhexyloxy)-1,4-phenylene-vinylene]/CdS nanocomposites in a polyvinyl alcohol matrix/indium tin oxide device exhibit hysteresis, which is attributed to the trapping, storage, and emission of holes in the quantized valence band energy levels of isolated CdS nanoneedles. The characteristics at different operating frequencies show that the hysteresis is due to trapping of charge carriers in CdS nanocomposites rather than in the interfacial states. The memory behavior in the inorganic/organic heterostructure is explained on the basis of a simple energy band diagram.

  9. Benign proliferative nipple duct lesions frequently contain CAM 5.2 and anti-cytokeratin 7 immunoreactive cells in the overlying epidermis.

    Science.gov (United States)

    Zeng, Z; Melamed, J; Symmans, P J; Cangiarella, J F; Shapiro, R L; Peralta, H; Symmans, W F

    1999-11-01

    Benign proliferative nipple duct lesions (PNDLs) pose a diagnostic problem for clinicians and pathologists. Clinically, they may be associated with skin changes typically present in Paget's disease of the nipple. The identification of numerous scattered cells in the epidermis that are immunoreactive for low-molecular-weight cytokeratin may lead to further confusion with Paget's disease. We studied the nipple epidermis in nine cases of PNDL and compared them with 26 histologically normal nipples from mastectomy specimens. CAM 5.2 and anticytokeratin 7 (CK7) immunoreactive cells were identified in the epidermis of seven of nine nipples associated with PNDL. The cytokeratin-positive cells appeared cytologically benign and were dispersed singly (scattered in seven of seven cases and frequent in four of seven cases) or formed small aggregates with occasional tubular structures (three of seven cases) in the basal and middle layers of the epidermis. In two of seven cases, these epidermal immunoreactive cells showed continuity with the underlying PNDL, suggesting the spread or continuation of lesional cells to the epidermis. Dispersed single immunoreactive cells were identified in small numbers (scattered) in the basal layer of the epidermis in 12 of 26 normal nipples and more frequently in 1 of 12 cases. In all cases, the intraepidermal cells were negative for carcinoembryonic antigen (CEA) and Her-2/neu. We conclude that intraepidermal CAM 5.2 and anti-CK7 immunoreactive cells, which are normally present in the nipple epidermis, may proliferate and form aggregates when there is an underlying PNDL. The presence of these cells does not imply Paget's disease when the intraepidermal cells have a bland cytologic appearance, fail to overexpress Her-2/neu, and there is no carcinoma within the PNDL or elsewhere in the breast.

  10. 5-(2-Carboxyethenyl) isatin derivative induces G{sub 2}/M cell cycle arrest and apoptosis in human leukemia K562 cells

    Energy Technology Data Exchange (ETDEWEB)

    Zhou, Yao; Zhao, Hong-Ye; Han, Kai-Lin; Yang, Yao; Song, Bin-Bin; Guo, Qian-Nan [Key Laboratory of Industrial Microbiology, Ministry of Education, College of Biotechnology, Tianjin University of Science and Technology, Tianjin 300457 (China); Tianjin Key Laboratory of Industry Microbiology, College of Biotechnology, Tianjin University of Science and Technology, Tianjin 300457 (China); Fan, Zhen-Chuan [Key Laboratory of Food Nutrition and Safety (Tianjin University of Science and Technology), Ministry of Education, Tianjin 300457 (China); Obesita and Algaegen LLC, College Station, TX 77845 (United States); Zhang, Yong-Min [Université Pierre et Marie Curie-Paris 6, Institut Parisien de Chimie Moléculaire UMR CNRS 8232, 4 Place Jussieu, 75005 Paris (France); Teng, Yu-Ou, E-mail: tyo201485@tust.edu.cn [Key Laboratory of Industrial Microbiology, Ministry of Education, College of Biotechnology, Tianjin University of Science and Technology, Tianjin 300457 (China); Tianjin Key Laboratory of Industry Microbiology, College of Biotechnology, Tianjin University of Science and Technology, Tianjin 300457 (China); Yu, Peng, E-mail: yupeng@tust.edu.cn [Key Laboratory of Industrial Microbiology, Ministry of Education, College of Biotechnology, Tianjin University of Science and Technology, Tianjin 300457 (China); Tianjin Key Laboratory of Industry Microbiology, College of Biotechnology, Tianjin University of Science and Technology, Tianjin 300457 (China)

    2014-08-08

    Highlights: • 5-(2-Carboxyethenyl) isatin derivative (HKL 2H) inhibited K562’s proliferation. • HKL 2H caused the morphology change of G{sub 2}/M phase arrest and typical apoptosis. • HKL 2H induced G2/M cell cycle phase arrest in K562 cells. • HKL 2H induced apoptosis in K562 cells through the mitochondrial pathway. - Abstract: Our previous study successfully identified that the novel isatin derivative (E)-methyl 3-(1-(4-methoxybenzyl)-2,3-dioxoindolin-5-yl) acrylate (HKL 2H) acts as an anticancer agent at an inhibitory concentration (IC{sub 50}) level of 3 nM. In this study, the molecular mechanism how HKL 2H induces cytotoxic activity in the human chronic myelogenous leukemia K562 cells was investigated. Flow cytometric analysis showed that the cells were arrested in the G{sub 2}/M phase and accumulated subsequently in the sub-G{sub 1} phase in the presence of HKL 2H. HKL 2H treatment down-regulated the expressions of CDK1 and cyclin B but up-regulated the level of phosphorylated CDK1. Annexin-V staining and the classic DNA ladder studies showed that HKL 2H induced the apoptosis of K562 cells. Our study further showed that HKL 2H treatment caused the dissipation of mitochondrial membrane potential, activated caspase-3 and lowered the Bcl-2/Bax ratio in K562 cells, suggesting that the HKL 2H-causing programmed cell death of K562 cells was caused via the mitochondrial apoptotic pathway. Taken together, our data demonstrated that HKL 2H, a 5-(2-carboxyethenyl) isatin derivative, notably induces G{sub 2}/M cell cycle arrest and mitochondrial-mediated apoptosis in K562 cells, indicating that this compound could be a promising anticancer candidate for further investigation.

  11. Synthesis and crystal structures of 7-bromo-5-(2‧-chloro)phenyl-3-hydroxy-1-methyl-1,2-dihydro-3H-1,4-benzodiazepin-2-one and 7-bromo-5-(2‧-chloro)phenyl-1-hexyl-1,2,4,5-tetrahydro-3H-1,4-benzodiazepin-2,3-dione

    Science.gov (United States)

    Kravtsov, Victor Ch.; Fonari, Marina S.; Gdaniec, Мaria; Pavlovsky, Victor I.; Andronati, Sergei A.; Semenishyna, Ekaterina A.

    2012-06-01

    Treatment of 7-bromo-5-(2'-chloro)phenyl-3-hydroxy-1,2-dihydro-3H-1,4-benzodiazepin-2-one (1) with methyl or hexyl tosylate resulted in 7-bromo-5-(2'-chloro)phenyl-3-hydroxy-1-methyl-1,2-dihydro-3H-1,4-benzodiazepin-2-one (2) and 7-bromo-5-(2'-chloro)phenyl-1-hexyl-1,2,4,5-tetrahydro-3H-1,4-benzodiazepin-2,3-dione (3). As confirmed by X-ray crystallography, the two products differ not only in the identity of the alkyl substituent in position 1 of the benzodiazepine fragment but also crystallize in different molecular forms resulting from proton migration. This alteration of the molecular structure leads to a significant change in the conformation of the central molecular fragment and influences the assembly mode in the crystal. In 3, centrosymmetric dimers formed via a pair of Nsbnd H⋯O hydrogen bonds are further linked into chains via Csbnd Br⋯Odbnd C halogen bond interaction. In turn in 2 there are two symmetry independent molecules, each giving a different set of intermolecular interactions. One of the molecules forms a dimer via Osbnd H⋯O interactions whereas the second one generates chain via Csbnd Br⋯Odbnd C halogen bond that is also assisted by a weak Osbnd H⋯Br hydrogen bond.

  12. Typed Operational Semantics for Dependent Record Types

    Directory of Open Access Journals (Sweden)

    Yangyue Feng

    2011-03-01

    Full Text Available Typed operational semantics is a method developed by H. Goguen to prove meta-theoretic properties of type systems. This paper studies the metatheory of a type system with dependent record types, using the approach of typed operational semantics. In particular, the metatheoretical properties we have proved include strong normalisation, Church-Rosser and subject reduction.

  13. Characterization of non-classical Csbnd Br⋯π interactions in (E)-1,3-dibromo-5-(2-(ferrocenyl)vinyl)benzene and related derivatives of ferrocene

    Science.gov (United States)

    Shukla, Rahul; Panini, Piyush; McAdam, C. John; Robinson, Brian H.; Simpson, Jim; Tagg, Tei; Chopra, Deepak

    2017-03-01

    Amongst the halogens, the involvement of bromine atoms in various types of intermolecular interactions is comparatively the least studied. In this manuscript, we report the formation of Csbnd Br⋯π interactions, with the π-rings being the cyclopentadienyl (Cp) rings of a ferrocene molecule in a newly synthesized compound (E)-1,3-dibromo-5-(2-(ferrocenyl)vinyl)benzene. We have also performed a detailed quantitative analysis on Csbnd Br⋯π interactions observed in the synthesized molecule and in several related molecules found in the Cambridge Structure Database (CSD) showing the presence of these interactions. A topological analysis based upon QTAIM theory and electrostatic potential ESP mapped on the Hirshfeld surface of these molecules confirm that these interactions are better described as "halogen bonds" wherein the electropositive region (σ-hole) on the Br-atom interacts with the electronegative region over the Cp-ring of the ferrocene. Further, the electronegative region on the bromine atom (perpendicular to the Csbnd Br bond) was observed to be involved in the formation of highly directional Csbnd H⋯Br interactions with the ∠Csbnd Br⋯H close to 90°. Thus the bromine atom is acting as both a "halogen bond donor" and "hydrogen bond acceptor" in the crystal packing with the two interactions being mutually orthogonal.

  14. The Use of Nanoclays to Modify the Morphology and Photoluminescence of Electrospun Poly(9-vinylcarbazole)/Poly[2-methoxy-5-(2'-ethylhexyloxy)-1,4-phenylenevinylene] Blend Fibers

    Science.gov (United States)

    Balderas, Jesús-Uriel; Falcony, Ciro; Jiménez, Gloria-Lesly; Garzón, Amanda-Stephanie; Mondragón, Margarita

    2015-04-01

    The morphology and photoluminescence properties of electrospun poly(9-vinylcarbazole) (PVK)/poly[2-methoxy-5-(2'-ethylhexyloxy)-1,4-phenylenevinylene] (MEH-PPV) blend fibers, which were loaded with either halloysite clay nanotubes (HNTs) or an organically modified montmorillonite (OMMT) clay, were studied by scanning electron microscopy, transmission electron microscopy, and fluorescence spectroscopy. A concentration range of 0-30 wt.% was used for the clays, while the MEH-PPV concentration was fixed at 0.5 wt.%. Both clays, especially the OMMT clay, increased the phase separation of the components in the electrospun PVK/MEH-PPV blend fibers. This was attributed to their selective localization on the polymer phases. The HNTs and OMMT clay also increased energy transfer to the lowest energy states of MEH-PPV generated during electrospinning, and modified the amount of the partially overlapping conformation of carbazole groups (p-PVK) that constrained the aggregation of the PVK chains. These changes resulted in an increased emission from p-PVK, which varied depending on the type and concentration of the clay.

  15. Facts about Type 2

    Medline Plus

    Full Text Available ... In Honor Become a Member En Español Type 1 Type 2 About Us Online Community Meal Planning ... Basics Home Symptoms Diagnosis America's Diabetes Challenge Type 1 Type 2 Facts About Type 2 Enroll in ...

  16. Electronic and stereochemical characterizations of the photoinduced intermediates of nitrosyl complexes of metal (S = 5/2)-substituted hemoproteins trapped at low temperature.

    Science.gov (United States)

    Hori, H; Ikeda-Saito, M; Lang, G; Yonetani, T

    1990-09-05

    Low temperature photolysis of nitric oxide from the nitrosyl complexes of ferric myoglobin (NO-Fe(III)Mb) and manganese(II)-porphyrin-substituted myoglobin (NO-Mn(II)Mb) was examined by electron paramagnetic resonance (EPR) spectroscopy in order to elucidate the electronic and structural natures of the photoinduced intermediates of these hemoprotein-ligand complexes trapped at low temperature. The photoproduct of NO-Fe(III)Mb at 5 K exhibited entirely new X-band EPR absorptions in the magnetic field strength from 0 to 0.4 tesla. The widespread absorption together with distinct, sharp zero-field absorption was consistently observed in the photoproduct of the isoelectronic NO-Mn(II)Mb. These novel ERP signals indicate a spin-coupled pair with an effective spin of S = 2 between the high spin metal center (S = 5/2) and the photodissociated NO (S = 1/2) trapped adjacent to the metal center. On the other hand, the photolyzed form of nitrosyl complexes of Fe(III)- and Mn(II)-Glycera hemoglobins, in which the distal histidine of Mb is replaced by a leucyl residue, exhibited somewhat broader EPR absorptions similar to those of the corresponding native Fe(III)- or unliganded Mn(II)-Glycera hemoglobins, respectively, indicating that the photodissociated NO molecule moved farther away from the metal center in the heme pocket. These observations show the importance of the interaction of the distal residue with the ligand in determining the nature of the photolyzed states.

  17. Synthesis, experimental, theoretical characterization and biological activities of 4-ethyl-5-(2-hydroxyphenyl)-2H-1,2,4-triazole-3(4H)-thione

    Science.gov (United States)

    Koparir, Metin; Orek, Cahit; Koparir, Pelin; Sarac, Kamiran

    2013-03-01

    This work presents the characterization of 4-ethyl-5-(2-hydroxyphenyl)-2H-1,2,4-triazole-3(4H)-thione (III) by quantum chemical calculations and spectral techniques. The molecular geometry, vibrational frequencies and gauge including atomic orbital (GIAO) 1H and 13C NMR chemical shift values of III in the ground state have been calculated using the density functional method (B3LYP) with the 6-31G(d) basis set. The calculated results show that the optimized geometry can well reproduce the crystal structure, and the theoretical vibrational frequencies and chemical shift values show good agreement with experimental values. To determine conformational flexibility, the molecular energy profile of the title compound was obtained by DFT calculations with respect to the selected torsion angle, which was varied from -180° to +180° in steps of 10°. The energetic behavior of III in solvent media was examined using the B3LYP method with the 6-31G(d) basis set by applying the Onsager and the polarizable continuum model (PCM). The predicted nonlinear optical properties of III are greater than ones of urea. In addition, DFT calculations of molecular electrostatic potentials and frontier molecular orbitals of III were carried out at the B3LYP/6-31G(d) level of theory. The title compound was screened for antibacterial, antifungal and antioxidant activities.

  18. Two year follow-up of astigmatism after phacoemulsification with adjusted and unadjusted sutured versus sutureless 5.2 mm superior scleral incisions.

    Science.gov (United States)

    Lyhne, N; Corydon, L

    1998-12-01

    To evaluate changes in astigmatism 6 months to 2 years after 5.2 mm superior scleral incision phacoemulsification using 3 closures. Department of Ophthalmology, Vejle Hospital, Vejle, Denmark. This long-term follow-up study included 75 consecutive phacoemulsification patients who were randomly allocated to 1 of 3 incision closures: 1 intraoperatively adjusted cross suture, 1 unadjusted cross suture, no suture. Postoperative astigmatism after 1 and 2 years was evaluated by keratometric cylinder, induced astigmatism (Naeser's polar values), induced cylinder (Jaffe's vector analysis), and vector decomposition (Olsen). The data were compared with 1 week values. In the previous study, median astigmatism after 6 months was similar in all 3 groups, but only the sutureless group showed early stability. Significant against-the-rule (ATR) changes were seen in the sutured cases (P suture group exhibited stability after 6 months, while the unadjusted-suture group showed a further tendency to change ATR. At 2 years, median ranges of astigmatism were -0.49 to -0.90 diopter (D) (Naeser), 0.77 to 1.02 D (Jaffe), and 96% to 98% ATR (Olsen). The intergroup differences were not statistically significant. Two year follow-up confirmed that sutureless closure led to early astigmatism stability. Using a suture prolonged the postoperative period of astigmatism instability, and if used without intraoperative adjustment, a tendency toward a less predictable outcome persisted after 2 years.

  19. 5.2-GHz RF Power Harvester in 0.18-/spl mu/m CMOS for Implantable Intraocular Pressure Monitoring

    KAUST Repository

    Ouda, Mahmoud H.

    2013-04-17

    A first fully integrated 5.2-GHz CMOS-based RF power harvester with an on-chip antenna is presented in this paper. The design is optimized for sensors implanted inside the eye to wirelessly monitor the intraocular pressure of glaucoma patients. It includes a five-stage RF rectifier with an on-chip antenna, a dc voltage limiter, two voltage sensors, a low dropout voltage regulator, and MOSCAP based on-chip storage. The chip has been designed and fabricated in a standard 0.18-μm CMOS technology. To emulate the eye environment in measurements, a custom test setup is developed that comprises Plexiglass cavities filled with saline solution. Measurements in this setup show that the proposed chip can be charged to 1 V wirelessly from a 5-W transmitter 3 cm away from the harvester chip. The energy that is stored on the 5-nF on-chip MOSCAP when charged to 1 V is 2.5 nJ, which is sufficient to drive an arbitrary 100-μW load for 9 μs at regulated 0.8 V. Simulated efficiency of the rectifier is 42% at -7 dBm of input power.

  20. Enhancement of optical gain and amplified spontaneous emission due to waveguide geometry in the conjugated polymer poly[2-methoxy-5-(2'-ethylhexyloxy)-p-phenylene vinylene

    Science.gov (United States)

    Lampert, Zach E.; Papanikolas, John M.; Lewis Reynolds, C.

    2013-02-01

    We report enhanced amplified spontaneous emission (ASE) and optical gain performance in a conjugated polymer (CP)-based thin film waveguide (WG) Si(100)/SiO2/poly[2-methoxy-5-(2'-ethylhexyloxy)-p-phenylene vinylene] (MEH-PPV) by encapsulating the active layer with a transparent dielectric film of poly(methyl methacrylate) (PMMA). With index matched SiO2 and PMMA claddings, symmetric WGs are formed that exhibit increased mode confinement and reduced propagation loss enabling lower ASE threshold (40%) and higher optical gain (50%) compared to Si(100)/SiO2/MEH-PPV/air asymmetric WGs. An extremely large net gain coefficient of 500 cm-1 is achieved under picosecond pulse excitation, which is >4× larger than values previously reported in the literature. Fabrication of symmetric WGs requires no complex processing techniques, thus offering a simple, low-cost approach for effectively controlling the ASE behavior of CP-based WGs and related optical devices.

  1. Critical phenomena in a mixed spin-3/2 and spin-5/2 Ising ferro-ferrimagnetic system in a longitudinal magnetic field

    Science.gov (United States)

    De La Espriella, N.; Madera, J. C.; Buendía, G. M.

    2017-11-01

    We apply Monte Carlo simulation techniques to study the magnetic behavior of a mixed Ising system on a square lattice, where spins SA = ± 3 / 2, ± 1 / 2 alternate with spins σB = ± 5 / 2, ± 3 / 2, ± 1 / 2 in two interpenetrating sublattices A and B, respectively. The Hamiltonian of the system contains an exchange interaction between nearest neighbors and a longitudinal magnetic field. In order to understand the differences between a mixed Ising system with competing interactions with one with cooperating ones, we study both cases, the ferrimagnetic and the ferromagnetic exchange interactions. We calculate the dependence of the total magnetization, the sublattice magnetizations, the energy, and the magnetic susceptibility, with the magnetic field, and their temperature dependence for a fixed field. We found that under the influence of the magnetic field the ferrimagnetic system presents an interesting phenomena associated with a reversal of the sublattice magnetizations at low temperatures. We found that our system has no compensation temperatures. In both, the ferri and the antiferromagnetic cases, the magnetic field smooths the transition between the ordered and the paramagnetic phase. Finally we present a phase diagram with the critical temperatures in terms of the magnetic field for the ferri and ferromagnetic cases.

  2. Critical and compensation behavior of a mixed spin-5/2 and spin-3/2 Ising antiferromagnetic system in a core/shell nanowire

    Science.gov (United States)

    Alzate-Cardona, J. D.; Barrero-Moreno, M. C.; Restrepo-Parra, E.

    2017-11-01

    In this work, Monte Carlo simulations based on metropolis algorithm were performed to study the critical and compensation temperatures of a core-shell nanowire with spins S=+/-\\frac{5}{2}, +/-\\frac{3}{2}, +/-\\frac{1}{2} and σ=+/-\\frac{3}{2}, +/-\\frac{1}{2} , respectively, considering an Ising antiferromagnetic system. The influence of nearest neighbors exchange interactions and crystal field anisotropy on the critical and compensation behaviors of the system has been analyzed. The effects of the nanowire height in the critical and compensation temperatures were evaluated. The results show that, for a system with given values of exchange interaction constants and crystal field anisotropy, a compensation point only appears if two requirements are satisfied. First, the weight of the core magnetization in the total magnetization must be greater than the weight of the shell magnetization at zero temperature. And second, the exchange constant of shell ions must be greater than a certain value. This value is, at the same time, greater than the exchange constant of core ions. The critical and compensation temperatures are very sensitive to variations in the exchange constant of the shell ions and core ions, respectively, while the crystal field anisotropy affects both temperatures.

  3. Antimicrobial activity of PVP from an Antarctic bacterium, Janthinobacterium sp. Ant5-2, on multi-drug and methicillin resistant Staphylococcus aureus

    KAUST Repository

    Huang, Jonathan P.

    2012-04-11

    Multiple drug resistant (MDR) and methicillin-resistant Staphylococcus aureus (MRSA) have become increasingly prevalent as a community acquired infection. As a result limited treatment options are available with conventional synthetic antibiotics. Bioprospecting natural products with potent antimicrobial activity show promise for developing new drugs against this pathogen. In this study, we have investigated the antimicrobial activity of a purple violet pigment (PVP) from an Antarctic bacterium, Janthinobacterium sp. Ant5-2 on 15 clinical MDR and MRSA strains. The colorimetric resazurin assay was employed to determine the minimum inhibitory concentration (MIC90) of PVP against MDR and MRSA. The MIC90 ranged between 1.57 µg/mL and 3.13 µg/mL, which are significantly lower than many antimicrobials tested from natural sources against this pathogen. The spectrophotometrically determined growth analysis and total microscopic counts using Live/dead® BacLight™ fluorescent stain exhibited a steady decrease in viability of both MDR and MRSA cultures following treatment with PVP at the MIC levels. In silico predictive molecular docking study revealed that PVP could be a DNA-targeting minor groove binding antimicrobial compound. The continued development of novel antimicrobials derived from natural sources with the combination of a suite of conventional antibiotics could stem the rising pandemic of MDR and MRSA along with other deadly microbial pathogens.

  4. Structural properties and bonding nature of 3-methyl-4-phenyl-5-(2-pyridyl)-1,2,4-triazole single crystal

    Energy Technology Data Exchange (ETDEWEB)

    Reshak, Ali Hussain, E-mail: maalidph@yahoo.com [Institute of Physical Biology-South Bohemia University, Nove Hrady 37333 (Czech Republic); School of Material Engineering, Malaysia University of Perlis, P.O. Box 77, d/a Pejabat Pos Besar, 01007 Kangar, Perlis (Malaysia); Stys, Dalibor [Institute of Physical Biology-South Bohemia University, Nove Hrady 37333 (Czech Republic); Auluck, S. [National Physical Laboratory, Dr. K S Krishnan Marg, New Delhi 110012 (India); Kityk, I.V. [Electrical Engineering Department, Technological University of Czestochowa, Al.Armii Krajowej 17/19, Czestochowa (Poland); Kamarudin, H. [School of Material Engineering, Malaysia University of Perlis, P.O. Box 77, d/a Pejabat Pos Besar, 01007 Kangar, Perlis (Malaysia)

    2011-10-17

    Highlights: {yields} The atomic positions were optimized. {yields} The optimization done by minimization of the forces. {yields} The crystal possess direct gap. - Abstract: The atomic positions of 3-methyl-4-phenyl-5-(2-pyridyl)-1,2,4-triazole single crystal taken from the X-ray diffraction data obtained by Liu et al. were optimized by minimization of the forces acting on the atoms using a full potential linear augmented plane wave method within density-functional theory. The local density approximation (LDA) by Ceperley-Alder (CA) exchange-correlation potential was applied. The full potential calculations show that the valence band maximum (VBM) and conduction band minimum (CBM) are located at {Gamma} point of the Brillouin zone resulting in a direct energy gap of 3.4 eV for the original experimental structure and 3.2 eV for the optimized structure. The upper VB is formed mainly by C, H, and N atoms while the lower CB has mainly C and H atoms. We present an analysis of the partial densities of states which gives useful information on hybridization and the orbital character of the states. We have calculated the bond lengths and angles, a good agreement with the experimental data were found. The origin of the chemical bonding and the electronic charge density contour in the (1 0 0) and (1 1 0) planes were analyzed.

  5. The intense starburst HDF 850.1 in a galaxy overdensity at z ≈ 5.2 in the Hubble Deep Field.

    Science.gov (United States)

    Walter, Fabian; Decarli, Roberto; Carilli, Chris; Bertoldi, Frank; Cox, Pierre; Da Cunha, Elisabete; Daddi, Emanuele; Dickinson, Mark; Downes, Dennis; Elbaz, David; Ellis, Richard; Hodge, Jacqueline; Neri, Roberto; Riechers, Dominik A; Weiss, Axel; Bell, Eric; Dannerbauer, Helmut; Krips, Melanie; Krumholz, Mark; Lentati, Lindley; Maiolino, Roberto; Menten, Karl; Rix, Hans-Walter; Robertson, Brant; Spinrad, Hyron; Stark, Dan P; Stern, Daniel

    2012-06-13

    The Hubble Deep Field provides one of the deepest multiwavelength views of the distant Universe and has led to the detection of thousands of galaxies seen throughout cosmic time. An early map of the Hubble Deep Field at a wavelength of 850 micrometres, which is sensitive to dust emission powered by star formation, revealed the brightest source in the field, dubbed HDF 850.1 (ref. 2). For more than a decade, and despite significant efforts, no counterpart was found at shorter wavelengths, and it was not possible to determine its redshift, size or mass. Here we report a redshift of z = 5.183 for HDF 850.1, from a millimetre-wave molecular line scan. This places HDF 850.1 in a galaxy overdensity at z ≈ 5.2, corresponding to a cosmic age of only 1.1 billion years after the Big Bang. This redshift is significantly higher than earlier estimates and higher than those of most of the hundreds of submillimetre-bright galaxies identified so far. The source has a star-formation rate of 850 solar masses per year and is spatially resolved on scales of 5 kiloparsecs, with an implied dynamical mass of about 1.3 × 10(11) solar masses, a significant fraction of which is present in the form of molecular gas. Despite our accurate determination of redshift and position, a counterpart emitting starlight remains elusive.

  6. A 5.2GHz, 0.5mW RF powered wireless sensor with dual on-chip antennas for implantable intraocular pressure monitoring

    KAUST Repository

    Arsalan, Muhammad

    2013-06-01

    For the first time a single chip implantable wireless sensor system for Intraocular Pressure Monitoring (IOPM) is presented. This system-on-chip (SoC) is battery-free and harvests energy from incoming RF signals. The chip is self-contained and does not require external components or bond wires to function. This 1.4mm3 SoC has separate 2.4GHz-transmit and 5.2GHz-receive antennas, an energy harvesting module, a temperature sensor, a 7-bit TIQ Flash ADC, a 4-bit RFID, a power management and control unit, and a VCO transmitter. The chip is fabricated in a standard 6-metal 0.18μm CMOS process and is designed to work with a post-processed MEMS pressure sensor. It consumes 513μW of peak power and when implanted inside the eye, it is designed to communicate with an external reader using on-off keying (OOK). © 2013 IEEE.

  7. Facile metalation of Hbzq by [cis-Pt(C6F5)2(thf)2]: a route to a pentafluorophenyl benzoquinolate solvate complex that easily coordinates terminal alkynes. Spectroscopic and optical properties.

    Science.gov (United States)

    Berenguer, Jesús R; Lalinde, Elena; Moreno, M Teresa; Sánchez, Sergio; Torroba, Javier

    2012-11-05

    A new neutral cyclometalated platinum(II) solvate complex [cis-Pt(bzq)(C(6)F(5))(acetone)] (1) has been prepared by easy C-H activation of 7,8-benzo[h]quinoline on the coordination sphere of [cis-Pt(C(6)F(5))(2)(thf)(2)] (thf = tetrahydrofuran). The study of the reaction pathway has led us to the preparation of the bis(Hbzq) product [cis-Pt(C(6)F(5))(2)(Hbzq)(2)] (2) and the benzoquinoline-benzoquinolate derivative [Pt(bzq)(C(6)F(5))(Hbzq)] (3). This latter complex has been characterized by X-ray diffraction, showing the occurrence of π···π intermolecular stacking interactions associated to the deprotonated bzq units. The acetone molecule in [cis-Pt(bzq)(C(6)F(5))(acetone)] can be easily displaced by alkynes, allowing the synthesis of the first reported η(2)-alkyne-cycloplatinate complexes [Pt(bzq)(C(6)F(5))(η(2)-RC≡CR')] (R = H, R' = Ph 4, (t)Bu 5, Fc 6; R = R' = Ph 7), which have been fully characterized spectroscopically and by DFT studies. These alkyne complexes are only moderately stable in solution, and all attempts to obtain crystals suitable for X-ray diffraction were fruitless. Nevertheless, in the case of the ferrocenyl derivative, crystals of complex [Pt(κN:η(2)-bzq-C≡CFc)(C(6)F(5))(μ-κC(α):η(2)-C≡CFc)Pt(bzq)(C(6)F(5))] (8), containing an unusual alkynyl-functionalized benzoquinoline chelate ligand, were systematically obtained. All complexes (except those containing the ferrocenyl fragment) present emissive properties in solution and solid state (77 K), related, in general, with intraligand (bzq) excited states with some mixing (3)MLCT character, as supported by theoretical calculations. In solid state at room temperature, aggregation induced emission (AIE) is observed likely generated by intermolecular π···π stacking, as supporting by DFT calculations on 3(2). Interestingly, both types of excited states ((3)IL/(3)MLCT and AIE) seem to be close in energy in complexes 1 and 3, which show a significant luminescent thermochromism

  8. Electronic band structure, Fermi surface, and elastic properties of polymorphs of the 5.2 K iron-free superconductor SrPt2As2 from first-principles calculations

    Science.gov (United States)

    Shein, I. R.; Ivanovskii, A. L.

    2011-03-01

    By means of first-principles calculations, we studied in detail the structural, elastic, and electronic properties of the tetragonal CaBe2Ge2-type 5.2 K superconductor SrPt2As2 in comparison with two hypothetical SrPt2As2 polymorphs with ThCr2Si2-type structures, which differ in the atomic configurations of the [Pt2As2] (or [As2Pt2]) blocks. We found that CaBe2Ge2-type SrPt2As2 is a unique system with near-Fermi bands of a complicated character and an “intermediate”-type Fermi surface, which consists of electronic pockets having a cylinderlike [two-dimensional (2D)] topology (typical of 122 FeAs phases) together with 3D-like electronic and hole pockets, which are characteristic of ThCr2Si2-like iron-free low-Tc superconductors. Our analysis revealed that, as distinct from ThCr2Si2-like 122 phases, other features of CaBe2Ge2-like SrPt2As2 are as follows: (1) There are essential differences in the contributions from [Pt2As2] and [As2Pt2] blocks to the near-Fermi region; conduction is anisotropic and occurs mainly in the [Pt2As2] blocks. (2) A 3D system of strong covalent Pt-As bonds is formed (inside and between [Pt2As2] and [As2Pt2] blocks), which is responsible for enhanced stability of this polymorph. (3) There is essential charge anisotropy between adjacent [Pt2As2] and [As2Pt2] blocks. We also predict that CaBe2Ge2-like SrPt2As2 is a mechanically stable and relatively soft material with high compressibility, which will behave in a ductile manner. In contrast, the ThCr2Si2-type SrPt2As2 polymorphs, which contain only [Pt2As2] or [As2Pt2] blocks, are less stable, have Fermi surfaces of a multisheet three-dimensional type like the ThCr2Si2-like iron-free 122 phases, and therefore will be ductile materials with high elastic anisotropy. Based on our data for the three simplest SrPt2As2 polymorphs we assume that there may exist a family of higher-order polytypes, which can be formed as a result of various stackings of the two main types of building blocks ([Pt2As2

  9. Efectividad Del 2-Bromo-5-(2-Bromo-2-Nitrovinil)-Furano en formulación oleosa en el tratamiento de la metritis puerperal en vacas (Effetiveness of 2-Bromo-5-(2-Bromo-2-Nitrovinil)-Furano oleaginous formulation in the treatment of puerperal metritis in cattle)

    OpenAIRE

    Hernández Barreto, Miguel A.; Silveira Prado, Enrique A; Antonio Martínez del Pino; Oraida González García

    2006-01-01

    El ensayo se realizó en 46 hembras bovinas que presentaron síntomas clínicos evidentes de metritis puerperal séptica, a las cuales se le aplicó aleatoriamente por vía transcervical, previa evacuación del contenido uterino por vía rectal, uno de los siguientes esquemas de tratamiento: tetraciclina amortiguada o el producto vinil-furánico 2-bromo-5-(2-bromo-2-nitrovinil)-furano (denominado G-1) al 0,15g% en aceite vegetal. Se compararon en ambos grupos la recuperación clínico-reproductiva, fecu...

  10. Multi-model ensemble projections of European river floods and high flows at 1.5, 2, and 3 degrees global warming

    Science.gov (United States)

    Thober, Stephan; Kumar, Rohini; Wanders, Niko; Marx, Andreas; Pan, Ming; Rakovec, Oldrich; Samaniego, Luis; Sheffield, Justin; Wood, Eric F.; Zink, Matthias

    2018-01-01

    Severe river floods often result in huge economic losses and fatalities. Since 1980, almost 1500 such events have been reported in Europe. This study investigates climate change impacts on European floods under 1.5, 2, and 3 K global warming. The impacts are assessed employing a multi-model ensemble containing three hydrologic models (HMs: mHM, Noah-MP, PCR-GLOBWB) forced by five CMIP5 general circulation models (GCMs) under three Representative Concentration Pathways (RCPs 2.6, 6.0, and 8.5). This multi-model ensemble is unprecedented with respect to the combination of its size (45 realisations) and its spatial resolution, which is 5 km over the entirety of Europe. Climate change impacts are quantified for high flows and flood events, represented by 10% exceedance probability and annual maxima of daily streamflow, respectively. The multi-model ensemble points to the Mediterranean region as a hotspot of changes with significant decrements in high flows from ‑11% at 1.5 K up to ‑30% at 3 K global warming mainly resulting from reduced precipitation. Small changes (climate variability, downscaling technique, and hydrologic model parameters, the contribution by the GCMs to the overall uncertainties of the ensemble is in general higher than that by the HMs. The latter, however, have a substantial share in the Mediterranean and Scandinavia. Adaptation measures for limiting the impacts of global warming could be similar under 1.5 K and 2 K global warming, but have to account for significantly higher changes under 3 K global warming.

  11. Morphology of the spectral resonance structure of the electromagnetic background noise in the range of 0.1–4 Hz at L = 5.2

    Directory of Open Access Journals (Sweden)

    A. G. Yahnin

    2003-03-01

    Full Text Available Continuous observations of fluctuations of the geomagnetic field at Sodankylä Geophysical Observatory (L = 5.2 were used for a comprehensive morphological study of the spectral resonance structure (SRS seen in the background electromagnetic noise in the frequency range of 0.1–4.0 Hz. It is shown that the occurrence rate of SRS is higher in the nighttime than in the daytime. The occurrence rate is higher in winter than in summer. The SRS frequencies and the difference between neighbouring eigenfrequencies (the frequency scale increase towards nighttime and decrease towards daytime. Both frequency scale and occurrence rate exhibit a clear tendency to decrease from minimum to maximum of the solar activity cycle. It is found that the occurrence rate of SRS decreases when geomagnetic activity increases. The SRS is believed to be a consequence of a resonator for Alfvén waves, which is suggested to exist in the upper ionosphere. According to the theory of the ionospheric Alfvén resonator (IAR, characteristics of SRS crucially depend on electron density in the F-layer maximum, as well as on the altitudinal scale of the density decay above the maximum.We compared the SRS morphological properties with predictions of the IAR theory. The ionospheric parameters needed for calculation were obtained from the ionosphere model (IRI-95, as well as from measurements made with the ionosonde in Sodankylä. We conclude that, indeed, the main morphological properties of SRS are explained on the basis of the IAR theory. The measured parameters of SRS can be used for improving the ionospheric models.Key words. Ionosphere (auroral ionosphere; wave propagation – Radio Science (electromagnetic noise and interference

  12. Morphology of the spectral resonance structure of the electromagnetic background noise in the range of 0.1–4 Hz at L = 5.2

    Directory of Open Access Journals (Sweden)

    J. Manninen

    Full Text Available Continuous observations of fluctuations of the geomagnetic field at Sodankylä Geophysical Observatory (L = 5.2 were used for a comprehensive morphological study of the spectral resonance structure (SRS seen in the background electromagnetic noise in the frequency range of 0.1–4.0 Hz. It is shown that the occurrence rate of SRS is higher in the nighttime than in the daytime. The occurrence rate is higher in winter than in summer. The SRS frequencies and the difference between neighbouring eigenfrequencies (the frequency scale increase towards nighttime and decrease towards daytime. Both frequency scale and occurrence rate exhibit a clear tendency to decrease from minimum to maximum of the solar activity cycle. It is found that the occurrence rate of SRS decreases when geomagnetic activity increases. The SRS is believed to be a consequence of a resonator for Alfvén waves, which is suggested to exist in the upper ionosphere. According to the theory of the ionospheric Alfvén resonator (IAR, characteristics of SRS crucially depend on electron density in the F-layer maximum, as well as on the altitudinal scale of the density decay above the maximum.We compared the SRS morphological properties with predictions of the IAR theory. The ionospheric parameters needed for calculation were obtained from the ionosphere model (IRI-95, as well as from measurements made with the ionosonde in Sodankylä. We conclude that, indeed, the main morphological properties of SRS are explained on the basis of the IAR theory. The measured parameters of SRS can be used for improving the ionospheric models.Key words. Ionosphere (auroral ionosphere; wave propagation – Radio Science (electromagnetic noise and interference

  13. Hydrostatic, uniaxial, and triaxial compression tests on unpoled "Chem-prep" PZT 95/5-2Nb ceramic within temperature range of -55 to 75 degrees C.

    Energy Technology Data Exchange (ETDEWEB)

    Zeuch, David Henry; Montgomery, Stephen Tedford; Lee, Moo Yul; Hofer, John H.

    2003-10-01

    Sandia is currently developing a lead-zirconate-titanate ceramic 95/5-2Nb (or PNZT) from chemically prepared ('chem-prep') precursor powders. Previous PNZT ceramic was fabricated from the powders prepared using a 'mixed-oxide' process. The specimens of unpoled PNZT ceramic from batch HF803 were tested under hydrostatic, uniaxial, and constant stress difference loading conditions within the temperature range of -55 to 75 C and pressures to 500 MPa. The objective of this experimental study was to obtain mechanical properties and phase relationships so that the grain-scale modeling effort can develop and test its models and codes using realistic parameters. The stress-strain behavior of 'chem-prep' PNZT under different loading paths was found to be similar to that of 'mixed-oxide' PNZT. The phase transformation from ferroelectric to antiferroelectric occurs in unpoled ceramic with abrupt increase in volumetric strain of about 0.7 % when the maximum compressive stress, regardless of loading paths, equals the hydrostatic pressure at which the transformation otherwise takes place. The stress-volumetric strain relationship of the ceramic undergoing a phase transformation was analyzed quantitatively using a linear regression analysis. The pressure (P{sub T1}{sup H}) required for the onset of phase transformation with respect to temperature is represented by the best-fit line, P{sub T1}{sup H} (MPa) = 227 + 0.76 T (C). We also confirmed that increasing shear stress lowers the mean stress and the volumetric strain required to trigger phase transformation. At the lower bound (-55 C) of the tested temperature range, the phase transformation is permanent and irreversible. However, at the upper bound (75 C), the phase transformation is completely reversible as the stress causing phase transformation is removed.

  14. Thermochemical properties of exo-tricyclo[5.2.1.0(2,6)]decane (JP-10 jet fuel) and derived tricyclodecyl radicals.

    Science.gov (United States)

    Hudzik, Jason M; Asatryan, Rubik; Bozzelli, Joseph W

    2010-09-09

    exo-Tricyclo[5.2.1.0(2,6)]decane (TCD) or exo-tetrahydrodicyclopentadiene is the principal component of the high-energy density hydrocarbon fuel commonly identified as JP-10. Thermodynamic parameters for the parent TCD molecule and of all the tricyclodecyl radicals corresponding to the loss of hydrogen atoms from different carbons sites (TCD-Ri with i indicating the given carbon center) are determined using several density functional theory and G3MP2B3 and CBS-QB3 higher level composite computational chemistry methods. Five isodesmic work reactions, three involving bridged hydrocarbon reference molecules with similar ring strains, are employed to produce a cancelation of systematic calculation errors in evaluation of standard, gas-phase formation enthalpies at 298 K. Delta(f)H degrees (298) for TCD is found to be -19.5 +/- 1.3 kcal mol(-1), which is several kcal mol(-1) lower than the commonly used values. C(i)-H bond energies for corresponding TCD carbon sites are evaluated as follows: TCD-R1, 107.2; TCD-R2, 100.1; TCD-R3, 98.0; TCD-R4, 98.5; TCD-R9, 98.7; TCD-R10, 104.1 kcal mol(-1). Results from use of five different DFT methods are in very good agreement with composite level values for all work reactions used for the radicals. The exo and endo isomers of TCD are both determined to have chair and boat conformers.

  15. Synthesis and antifungal activity of 2-azetidinonyl-5-(2-benzoylphenoxy)methyl-1,3,4-oxadiazoles against seed-borne pathogens of Eleusine coracana (L.) Gaertn.

    Science.gov (United States)

    Khanum, Shaukath A; Shashikanth, Sheena; Sathyanarayana, Syagadadu Giriyanna; Lokesh, Siddalingaiah; Deepak, Saligrama A

    2009-07-01

    Finger millet is a major food crop as well as feed and fodder for livestock, especially in regions of southern India. A sturdy crop to fluctuating environmental conditions, it can be cultivated in all seasons of the year. Leaf, neck and finger blast caused by Pyricularia grisea Sacc. and Bipolaris setariae (Saw.) Shoem, as well as leaf spot disease, Bipolaris nodulosa (Berk & M.A.Curtis) Shoem, are major production constraints in southern India. Apart from environmental conditions, the use of harvested seeds by farmers is a major reason for disease prevalence. Benzophenone analogues have been investigated for controlling phytopathogenic fungi. In addition, the most important applications of azetidin-2-ones are as antibiotics. Based on this information, the present study was conducted to explore the antifungal activity of integrated 2-azetidinonyl and 1,3,4-oxadiazoles moieties into a benzophenone framework. A simple high-yielding method for the integration of heterocyclic rings, namely 2-azetidinonyl, at the benzophenone nucleus has been achieved, starting from substituted 2-hydroxybenzophenones under mild conditions on a wet solid surface using microwave irradiation. In the present study, an array of newly synthesised compounds, 2-azetidinonyl-5-(2-benzoylphenoxy)methyl-1,3,4-oxadiazoles, were screened for their antifungal property against blast and leaf spot causing fungi associated with the seeds of finger millet, cv. Indof-9. Two of the newly synthesised compounds showed promising effects in depleting the incidence of seed-borne pathogenic fungi of finger millet. The suppression of Pyricularia grisea and Bipolaris setariae resulted in enhanced seed germination and seedling growth. (c) 2009 Society of Chemical Industry.

  16. Nebulized 0.5, 2.5 and 5 ml L-epinephrine for post-extubation stridor in children: a prospective, randomized, double-blind clinical trial.

    Science.gov (United States)

    da Silva, Paulo Sérgio Lucas; Fonseca, Marcelo Cunio Machado; Iglesias, Simone Brasil Oliveira; Junior, Emílio Lopes; de Aguiar, Vânia Euzébio; de Carvalho, Werther Brunow

    2012-02-01

    Nebulized L-epinephrine has been recommended for the treatment of viral croup. However, the few studies assessing its effect on post-extubation stridor (PES) have shown conflicting results. We compared the efficacy and safety of nebulized L-epinephrine at three different doses for the treatment of PES. We conducted a prospective, randomized, double-blind trial including all consecutive children with a PES score of ≥4 (Westley score). The primary efficacy outcome was change in PES score at 40 min. A reduction of ≥2 points in stridor score was defined as clinically significant. A total of 96 patients were randomly assigned to receive one of three doses of nebulized L-epinephrine upon achieving a PES score of 4 or more following extubation. Stridor score and vital signs were recorded before treatment, and at 20, 40, 60 and 180 min after nebulization. Baseline characteristics were similar among all study groups. No significant difference was detected among the treatments based on change in Westley score by intent-to-treat analysis. In addition, the difference in the number of patients who clinically improved among the treatment groups was not significant (p = 0.54). Patients receiving 5 ml nebulized epinephrine had a significant increase of systolic and diastolic blood pressure at 40 and 180 min. Nebulized L-epinephrine at doses of 0.5, 2.5 and 5 ml demonstrated a lack of dose response in effect on PES and a modestly clinically significant increase in undesired side effects (heart rate and blood pressure) at higher doses.

  17. The red-phase of poly[2-methoxy-5-(2-ethylhexyloxy)-1,4-phenylenevinylene] (MEH-PPV): a disordered HJ-aggregate.

    Science.gov (United States)

    Yamagata, Hajime; Hestand, Nicholas J; Spano, Frank C; Köhler, Anna; Scharsich, Christina; Hoffmann, Sebastian T; Bässler, Heinz

    2013-09-21

    The ratio of the 0-0 to 0-1 peak intensities in the photoluminescence (PL) spectrum of red-phase poly[2-methoxy-5-(2-ethylhexyloxy)-1,4-phenylenevinylene], better known as MEH-PPV, is significantly enhanced relative to the disordered blue-phase and is practically temperature independent in the range from T = 5 K to 180 K. The PL lifetime is similarly temperature independent. The measured trends are accounted for by modeling red-phase MEH-PPV as disordered π-stacks of elongated chains. Using the HJ-aggregate Hamiltonian expanded to include site disorder amongst electrons and holes, the absorption and PL spectra of cofacial MEH-PPV dimers are calculated. The PL 0-0/0-1 line strength ratio directly responds to the competition between intrachain interactions which promote J-aggregate-like behavior (enhanced PL ratio) and interchain interactions which promote H-aggregate-like behavior (attenuated PL ratio). In MEH-PPV aggregates, J-like behavior is favored by a relatively large intrachain exciton bandwidth--roughly an order of magnitude greater than the interchain bandwidth--and the presence of disorder. The latter is essential for allowing 0-0 emission at low temperatures, which is otherwise symmetry forbidden. For Gaussian disorder distributions consistent with the measured (inhomogeneous) line widths of the vibronic peaks in the absorption spectrum, calculations show that the 0-0 peak maintains its dominance over the 0-1 peak, with the PL ratio and radiative lifetime practically independent of temperature, in excellent agreement with experiment. Interestingly, interchain interactions lead only to about a 30% drop in the PL ratio, suggesting that the MEH-PPV π-stacks--and strongly disordered HJ-aggregates in general--can masquerade as single (elongated) chains. Our results may have important applications to other emissive conjugated polymers such as the β-phase of polyfluorenes.

  18. Compact Planar Ultrawideband Antennas with 3.5/5.2/5.8 GHz Triple Band-Notched Characteristics for Internet of Things Applications.

    Science.gov (United States)

    Dong, Jian; Li, Qianqian; Deng, Lianwen

    2017-02-10

    Ultrawideband (UWB) antennas, as core devices in high-speed wireless communication, are widely applied to mobile handsets, wireless sensor networks, and Internet of Things (IoT). A compact printed monopole antenna for UWB applications with triple band-notched characteristics is proposed in this paper. The antenna has a very compact size of 10 x 16 mm2 and is composed of a square slotted radiation patch and a narrow rectangular ground plane on the back of the substrate. First, by etching a pair of inverted T-shaped slots at the bottom of the radiation patch, one notched band at 5-6 GHz for rejecting the Wireless Local Area Network (WLAN) is generated. Then, by cutting a comb-shaped slot on the top of the radiation patch, a second notched band for rejecting 3.5 GHz Worldwide Interoperability for Microwave Access (WiMAX) is obtained. Further, by cutting a pair of rectangular slots and a C-shaped slot as well as adding a pair of small square parasitic patches at the center of the radiating patch, two separate notched bands for rejecting 5.2 GHz lower WLAN and 5.8 GHz upper WLAN are realized, respectively. Additionally, by integrating the slotted radiation patch with the narrow rectangular ground plane, an enhanced impedance bandwidth can be achieved, especially at the higher band. The antenna consists of linear symmetrical sections only and is easy for fabrication and fine-tuning. The measured results show that the designed antenna provides a wide impedance bandwidth of 150% from 2.12 to 14.80 GHz for VSWR good frequency-domain and time-domain performances at desired UWB frequencies and be an attractive candidate for portable IoT applications.

  19. Refining types using type guards in TypeScript

    NARCIS (Netherlands)

    de Wolff, Ivo Gabe; Hage, J.

    2017-01-01

    We discuss two adaptations of the implementation of type guards and narrowing in the TypeScript compiler. The first is an improvement on the original syntax-directed implementation, and has now replaced the original one in the TypeScript compiler. It is specifically suited for the scenario in which

  20. Guarded dependent type theory with coinductive types

    DEFF Research Database (Denmark)

    Bizjak, Aleš; Grathwohl, Hans Bugge; Clouston, Ranald

    2015-01-01

    We present guarded dependent type theory, gDTT, an extensional dependent type theory with a later' modality and clock quantifiers for programming and proving with guarded recursive and coinductive types. The later modality is used to ensure the productivity of recursive definitions in a modular...... functor rules for the later modality considered in earlier work, and are crucial for programming and proving with dependent types. We show soundness of the type theory with respect to a denotational model....

  1. Facts about Type 2

    Medline Plus

    Full Text Available ... Text Size: A A A Listen En Español Facts About Type 2 Type 2 diabetes is the ... 2, In this section Diabetes Basics Type 2 Facts About Type 2 Recently Diagnosed Treatment and Care ...

  2. Refinement Types for TypeScript

    OpenAIRE

    Vekris, Panagiotis; Cosman, Benjamin; Jhala, Ranjit

    2016-01-01

    We present Refined TypeScript (RSC), a lightweight refinement type system for TypeScript, that enables static verification of higher-order, imperative programs. We develop a formal core of RSC that delineates the interaction between refinement types and mutability. Next, we extend the core to account for the imperative and dynamic features of TypeScript. Finally, we evaluate RSC on a set of real world benchmarks, including parts of the Octane benchmarks, D3, Transducers, and the TypeScript co...

  3. The antiproliferative function of violacein-like purple violet pigment (PVP) from an Antarctic Janthinobacterium sp. Ant5-2 in UV-induced 2237 fibrosarcoma

    Science.gov (United States)

    Mojib, Nazia; Nasti, Tahseen H.; Andersen, Dale T.; Attigada, Venkatram R.; Hoover, Richard B.; Yusuf, Nabiha; Bej, Asim K.

    2013-01-01

    Background In this study, we have investigated the chemotherapeutic potential of a purple violet pigment (PVP), which was isolated from a previously undescribed Antarctic Janthinobacterium sp. (Ant5-2), against murine UV-induced 2237 fibrosarcoma and B16F10 melanoma cells. Methods The 2237, B16F10, C50, and NIH3T3 cells were treated with PVP at different doses and for different times, and their proliferation and viability were detected by 3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyltetrazolium bromide (MTT) assay. Cell cycle arrest induced by PVP in 2237 fibrosarcoma cells was assessed by flow cytometry and expression analysis of cell cycle regulatory proteins were done by Western blot. Apoptosis induced by PVP in 2237 cells was observed by annexin-V/propidium iodide double staining flow cytometry assay and fluorescence microscopy. To further determine the molecular mechanism of apoptosis induced by PVP, the changes in expression of Bcl-2, Bax and cytochrome c were detected by Western blot. The loss of mitochondrial membrane potential in PVP treated 2237 cells was assessed by staining with JC-1 dye following flow cytometry. Caspase-3, Caspase-9 and PARP cleavage were analyzed by Western blot and Caspase-3 and -9 activities were measured by colorimetric assays. Results In vitro treatment of murine 2237 cells with the PVP resulted in decreased cell viability (13–79%) in a time (24–72 h) and dose (0.1–1 μM)-dependent manner. The PVP-induced growth inhibition in 2237 cells was associated with both G0/G1 and G2/M phase arrest accompanied with decrease in the expression of cyclin dependent kinases (Cdks) and simultaneous increase in the expression of cyclin dependent kinase inhibitors (Cdki) – Cip1/p21 and Kip1/p27. Further, we observed a significant increase in the apoptosis of the 2237 fibrosarcoma cells which was associated with an increased expression of pro-apoptotic protein Bax, decreased expression of anti-apoptotic proteins Bcl-2, disruption of

  4. Compact Planar Ultrawideband Antennas with 3.5/5.2/5.8 GHz Triple Band-Notched Characteristics for Internet of Things Applications

    Directory of Open Access Journals (Sweden)

    Jian Dong

    2017-02-01

    Full Text Available Ultrawideband (UWB antennas, as core devices in high-speed wireless communication, are widely applied to mobile handsets, wireless sensor networks, and Internet of Things (IoT. A compact printed monopole antenna for UWB applications with triple band-notched characteristics is proposed in this paper. The antenna has a very compact size of 10 x 16 mm2 and is composed of a square slotted radiation patch and a narrow rectangular ground plane on the back of the substrate. First, by etching a pair of inverted T-shaped slots at the bottom of the radiation patch, one notched band at 5-6 GHz for rejecting the Wireless Local Area Network (WLAN is generated. Then, by cutting a comb-shaped slot on the top of the radiation patch, a second notched band for rejecting 3.5 GHz Worldwide Interoperability for Microwave Access (WiMAX is obtained. Further, by cutting a pair of rectangular slots and a C-shaped slot as well as adding a pair of small square parasitic patches at the center of the radiating patch, two separate notched bands for rejecting 5.2 GHz lower WLAN and 5.8 GHz upper WLAN are realized, respectively. Additionally, by integrating the slotted radiation patch with the narrow rectangular ground plane, an enhanced impedance bandwidth can be achieved, especially at the higher band. The antenna consists of linear symmetrical sections only and is easy for fabrication and fine-tuning. The measured results show that the designed antenna provides a wide impedance bandwidth of 150% from 2.12 to 14.80 GHz for VSWR < 2, except for three notched bands of 3.36–4.16, 4.92–5.36, and 5.68–6.0 GHz. Additionally, the antenna exhibits nearly omnidirectional radiation characteristics, low gain at the stopbands, and flat group delay over the whole UWB except at the stopbands. Simulated and experimental results show that the proposed antenna can provide good frequency-domain and time-domain performances at desired UWB frequencies and be an attractive candidate for

  5. Facts about Type 2

    Medline Plus

    Full Text Available ... Alert Day Diabetes Basics Home Symptoms Diagnosis America's Diabetes Challenge Type 1 Type 2 Facts About Type 2 Enroll in ... Where Do I Begin With Type2? Living With Type 1 Diabetes Enroll in the Living WIth Type 2 Diabetes ...

  6. metabolic control of type-2 diabetic patients commonly treated with ...

    African Journals Online (AJOL)

    Kateee

    2003-04-01

    Apr 1, 2003 ... of type 2 diabetes do not sustain glycaemic control. Objective: To assess metabolic control in type 2 diabetic patients predominantly treated with .... 1 (3.2). 5 (5.1). Alcohol consumption: • Yes (%). 23 (37.1)**. 5(21.7). 18 (46.2)a. 17(14.5). 2 (6.5). 15(17.4). Treatment. • Diet & exercise. 8(12.9). 2(8.7). 6(15.4).

  7. Synthesis of new N-benzoxazole and N-benzothiazole derivatives of 3-(4-substituted phenyl) aminoisoxazol-5(2H)-ones and comparison of their base induced rearrangement

    Energy Technology Data Exchange (ETDEWEB)

    Khalafy, Jabbar; Marjani, Ahmad Poursattar; Ebrahimlo, Ali Reza Molla [Urmia University, Urmia (Iran, Islamic Republic of). Dept. of Chemistry]. E-mail: jkhalafi@yahoo.com

    2006-05-15

    3-Arylaminoisoxazol-5(2H)-ones, substituted on nitrogen with benzoxazole and benzothiazole groups react with triethylamine in ethanol under reflux to afford the corresponding indole and imidazobenzothiazole derivatives, respectively. (author)

  8. Synthesis of new N-Benzoxazole and N-Benzothiazole derivatives of 3-(4-Substituted- phenylaminoisoxazol-5(2H-ones and comparison of their base induced rearrangement

    Directory of Open Access Journals (Sweden)

    Khalafy Jabbar

    2006-01-01

    Full Text Available 3-Arylaminoisoxazol-5(2H-ones, substituted on nitrogen with benzoxazole and benzothiazole groups react with triethylamine in ethanol under reflux to afford the corresponding indole and imidazobenzothiazole derivatives, respectively.

  9. Climate change alters low flows in Europe under global warming of 1.5, 2, and 3 °C

    Directory of Open Access Journals (Sweden)

    A. Marx

    2018-02-01

    Full Text Available There is growing evidence that climate change will alter water availability in Europe. Here, we investigate how hydrological low flows are affected under different levels of future global warming (i.e. 1.5, 2, and 3 K with respect to the pre-industrial period in rivers with a contributing area of more than 1000 km2. The analysis is based on a multi-model ensemble of 45 hydrological simulations based on three representative concentration pathways (RCP2.6, RCP6.0, RCP8.5, five Coupled Model Intercomparison Project Phase 5 (CMIP5 general circulation models (GCMs: GFDL-ESM2M, HadGEM2-ES, IPSL-CM5A-LR, MIROC-ESM-CHEM, NorESM1-M and three state-of-the-art hydrological models (HMs: mHM, Noah-MP, and PCR-GLOBWB. High-resolution model results are available at a spatial resolution of 5 km across the pan-European domain at a daily temporal resolution. Low river flow is described as the percentile of daily streamflow that is exceeded 90 % of the time. It is determined separately for each GCM/HM combination and warming scenario. The results show that the low-flow change signal amplifies with increasing warming levels. Low flows decrease in the Mediterranean region, while they increase in the Alpine and Northern regions. In the Mediterranean, the level of warming amplifies the signal from −12 % under 1.5 K, compared to the baseline period 1971–2000, to −35 % under global warming of 3 K, largely due to the projected decreases in annual precipitation. In contrast, the signal is amplified from +22 (1.5 K to +45 % (3 K in the Alpine region due to changes in snow accumulation. The changes in low flows are significant for regions with relatively large change signals and under higher levels of warming. However, it is not possible to distinguish climate-induced differences in low flows between 1.5 and 2 K warming because of (1 the large inter-annual variability which prevents distinguishing statistical estimates of period

  10. Bond Energies and Thermochemical Properties of Ring-Opened Diradicals and Carbenes of exo-Tricyclo[5.2.1.0(2,6)]decane.

    Science.gov (United States)

    Hudzik, Jason M; Castillo, Álvaro; Bozzelli, Joseph W

    2015-09-24

    Exo-tricyclo[5.2.1.0(2,6)]decane (TCD) or exo-tetrahydrodicyclopentadiene is an interesting strained ring compound and the single-component high-energy density hydrocarbon fuel known as JP-10. Important initial reactions of TCD at high temperatures could cleave a strained carbon-carbon (C-C) bond in the ring system creating diradicals also constrained by the remaining ring system. This study determines the thermochemical properties of these diradicals (TCD-H2 mJ-nJ where m and n correspond to the cleaved carbons sites) including the carbon-carbon bond dissociation energy (C-C BDE) corresponding to the cleaved TCD site. Thermochemical properties including enthalpies (ΔH°f298), entropies (S(T)), heat capacities (Cp(T)), and C-H and C-C BDEs for the parent (TCD-H2 m-n), radical (TCD-H2 mJ-n and m-nJ), diradical (TCD-H2 mJ-nJ), and carbene (TCD-H2 mJJ-n and m-nJJ) species are determined. Structures, vibrational frequencies, moments of inertia, and internal rotor potentials are calculated at the B3LYP/6-31G(d,p) level of theory. Standard enthalpies of formation in the gas phase for the TCD-H2 m-n parent and radical species are determined using the B3LYP density functional theory and the higher level G3MP2B3 and CBS-QB3 composite methods. For singlet and triplet TCD diradicals and carbenes, M06-2X, ωB97X-D, and CCSD(T) methods are included in the analysis to determine ΔH°f298 values. The C-C BDEs are further calculated using CASMP2(2,2)/aug-cc-pvtz//CASSCF(2,2)/cc-pvtz and with the CASMP2 energies extrapolated to the complete basis set limit. The bond energies calculated with these methods are shown to be comparable to the other calculation methods. Isodesmic work reactions are used for enthalpy analysis of these compounds for effective cancelation of systematic errors arising from ring strain. C-C BDEs range from 77.4 to 84.6 kcal mol(-1) for TCD diradical singlet species. C-H BDEs for the parent TCD-H2 m-n carbon sites range from 93 to 101 kcal mol(-1) with a

  11. The Last Interglacial-Glacial cycle (MIS 5-2) re-examined based on long proxy records from central and northern Europe

    Science.gov (United States)

    Helmens, Karin F.

    2014-02-01

    Current multi-proxy studies on a long sediment sequence preserved at Sokli (N Finland), i.e. in the central area of Fennoscandian glaciations, are drastically changing classic ideas of glaciations, vegetation and climate in northern Europe during the Late Pleistocene. The sediments in the Sokli basin have escaped major glacial erosion due to non-typical bedrock conditions. In this review, the Sokli record is compared in great detail with other long proxy records from central, temperate and northern, boreal Europe. These comprise the classic records of La Grande Pile (E France) and Oerel (N Germany) and more recently obtained records from Horoszki Duże (E Poland) and Lake Yamozero (NW Russia). The focus of the review is on pollen, lithology and macrofossil- and insect-based temperature inferences. The long records are further compared with recent proxy data from nearby terrestrial sites as well as with the rapidly accumulating high-resolution proxy data from the ocean realm. The comparison allows a re-examination of the environmental history and climate evolution of the Last Interglacial-Glacial (LI-G) cycle (MIS 5-2). It shows that environmental and climate conditions during MIS 5 (ca 130-70 ka BP) were distinctly different from those during MIS 4-2 (ca 70-15 ka BP). MIS 5 is characterized by three long forested intervals (broadly corresponding to MIS 5e, 5c, 5a), both in temperate and northern boreal Europe. These mild periods were interrupted by two short, relatively cold and dry intervals (MIS 5d and 5b) with mountain-centered glaciation in Fennoscandia. Millennial scale climate events were superimposed upon these longer lasting climate fluctuations. The time interval encompassing MIS 4-2 shows open vegetation. It is characterized by two glacial maxima (MIS 4 and 2) with sub-continental scale glaciation over northern Europe and dry conditions in strongly continental eastern European settings. High amplitude climate oscillations of millennial duration

  12. Syntheses and Characterization of W(NC6F5)F5- and W2(NC6F5)2F9- Salts and Computational Studies of the W(NR)F5- (R = H, F, CH3, CF3, C6H5, C6F5) and W2(NC6F5)2F9- Anions.

    Science.gov (United States)

    Turnbull, Douglas; Wetmore, Stacey D; Gerken, Michael

    2017-10-16

    Convenient preparative routes to fluorido[(pentafluorophenyl)imido]tungstate(VI) salts have been developed. The reaction of WF6·NC5H5 or [N(CH3)4][WF7] with C6F5NH2 results in quantitative formation of the C5H5NH+ or N(CH3)4+ salt of the W(NC6F5)F5- anion, respectively. The dissolution of [C5H5NH][W(NC6F5)F5] in anhydrous HF results in the formation of [C5H5NH][W2(NC6F5)2F9]. These salts have been comprehensively characterized in the solid state by X-ray crystallography and Raman spectroscopy and in solution by 19F and 1H NMR spectroscopy. The crystal structures of the W(NC6F5)F5- salts reveal conformational differences in the anions, and the 19F NMR spectra of these salts in CH3CN reveal coupling of the axial fluorido ligand to the 14N nucleus of the imido ligand. In addition, density functional theory (DFT-B3LYP) calculations have been performed on a series of W(NR)F5- anions (R = H, F, CH3, CF3, C6H5, C6F5) and the W2(NC6F5)2F9- anion, including gas-phase geometry optimizations, vibrational frequencies, molecular orbitals, and natural bond orbital (NBO) analyses.

  13. Crystal structures of two decavanadates(V with pentaaquamanganese(II pendant groups: (NMe42[V10O28{Mn(H2O5}2]·5H2O and [NH3C(CH2OH3]2[V10O28{Mn(H2O5}2]·2H2O

    Directory of Open Access Journals (Sweden)

    Maurício P. Franco

    2015-02-01

    Full Text Available Two heterometallic decavanadate(V compounds, bis(tetramethylammonium decaaquadi-μ4-oxido-tetra-μ3-oxido-hexadeca-μ2-oxido-hexaoxidodimanganese(IIdecavanadate(V pentahydrate, (Me4N2[V10O28{Mn(H2O5}2]·5H2O, A, and bis{[tris(hydroxymethylmethyl]ammonium} decaaquadi-μ4-oxido-tetra-μ3-oxido-hexadeca-μ2-oxido-hexaoxidodimanganese(IIdecavanadate(V dihydrate, [NH3C(CH2OH3]2[V10O28{Mn(H2O5}2]·2H2O, B, have been synthesized under mild reaction conditions in an aqueous medium. Both polyanions present two [Mn(OH25]2+ complex units bound to the decavanadate cluster through oxide bridges. In A, the decavanadate unit has 2/m symmetry, whereas in B it has twofold symmetry. Apart from this, the main differences between A and B rest on the organic cations, tetramethylammonium and [tris(hydroxymethylmethyl]ammonium, respectively, and on the number and arrangement of the water molecules of crystallization. In both compounds, the H atoms from the coordinating water molecules participate in extensive three-dimensional hydrogen-bonding networks, which link the cluster units both directly and through solvent molecules and, in B, through the `tris' cation hydroxyl groups. The cation in B also participates in N—H...O hydrogen bonds. A number of C—H...O interactions are also observed in both structures.

  14. Personality disorder types proposed for DSM-5.

    Science.gov (United States)

    Skodol, Andrew E; Bender, Donna S; Morey, Leslie C; Clark, Lee Anna; Oldham, John M; Alarcon, Renato D; Krueger, Robert F; Verheul, Roel; Bell, Carl C; Siever, Larry J

    2011-04-01

    The Personality and Personality Disorders Work Group has proposed five specific personality disorder (PD) types for DSM-5, to be rated on a dimension of fit: antisocial/psychopathic, avoidant, borderline, obsessive-compulsive, and schizotypal. Each type is identified by core impairments in personality functioning, pathological personality traits, and common symptomatic behaviors. The other DSM-IV-TR PDs and the large residual category of personality disorder not otherwise specified (PDNOS) will be represented solely by the core impairments combined with specification by individuals' unique sets of personality traits. This proposal has three main features: (1) a reduction in the number of specified types from 10 to 5; (2) description of the types in a narrative format that combines typical deficits in self and interpersonal functioning and particular configurations of traits and behaviors; and (3) a dimensional rating of the degree to which a patient matches each type. An explanation of these modifications in approach to diagnosing PD types and their justifications--including excessive co-morbidity among DSM-IV-TR PDs, limited validity for some existing types, lack of specificity in the definition of PD, instability of current PD criteria sets, and arbitrary diagnostic thresholds--are the subjects of this review.

  15. Facts about Type 2

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    Full Text Available ... Where Do I Begin With Type2? Living With Type 1 Diabetes Enroll in the Living WIth Type 2 Diabetes ... Low-Calorie Sweeteners Sugar and Desserts Fitness Exercise & Type 1 Diabetes Get Started Safely Get And Stay Fit Types ...

  16. Facts about Type 2

    Medline Plus

    Full Text Available ... Patient Education Materials — Taking Care of Type 2 Diabetes This two-page introduction to type 2 diabetes is in ... Forecast® magazine: lp-type-2, In this section Diabetes Basics Type 2 Facts About Type 2 Recently Diagnosed Treatment and ...

  17. Type Inference with Inequalities

    DEFF Research Database (Denmark)

    Schwartzbach, Michael Ignatieff

    1991-01-01

    Type inference can be phrased as constraint-solving over types. We consider an implicitly typed language equipped with recursive types, multiple inheritance, 1st order parametric polymorphism, and assignments. Type correctness is expressed as satisfiability of a possibly infinite collection...

  18. Distinct types of eigenvector localization in networks

    Science.gov (United States)

    Pastor-Satorras, Romualdo; Castellano, Claudio

    2016-01-01

    The spectral properties of the adjacency matrix provide a trove of information about the structure and function of complex networks. In particular, the largest eigenvalue and its associated principal eigenvector are crucial in the understanding of nodes’ centrality and the unfolding of dynamical processes. Here we show that two distinct types of localization of the principal eigenvector may occur in heterogeneous networks. For synthetic networks with degree distribution P(q) ~ q-γ, localization occurs on the largest hub if γ > 5/2 for γ centrality based on the non-backtracking matrix.

  19. Facts about Type 2

    Medline Plus

    Full Text Available ... a Member Donate Now! One Time Monthly In Memory In Honor Become a Member En Español Type 1 Type ... Diagnosing Diabetes and Learning About Prediabetes Type 2 Diabetes Risk Test Lower ...

  20. Types of Physical Activity

    Science.gov (United States)

    ... basics Types of physical activity Types of physical activity Not sure what kinds of physical activity you should do? Well, you need three main types of activity . They are aerobic (sometimes called "cardio"), muscle-strengthening , ...

  1. Guarded Cubical Type Theory

    DEFF Research Database (Denmark)

    Birkedal, Lars; Bizjak, Aleš; Clouston, Ranald

    2016-01-01

    terms. CTT provides a computational interpretation of functional extensionality, enjoys canonicity for the natural numbers type, and is conjectured to support decidable type-checking. Our new type theory, guarded cubical type theory (GCTT), provides a computational interpretation of extensionality......This paper improves the treatment of equality in guarded dependent type theory (GDTT), by combining it with cubical type theory (CTT). GDTT is an extensional type theory with guarded recursive types, which are useful for building models of program logics, and for programming and reasoning...... with coinductive types. We wish to implement GDTT with decidable type checking, while still supporting non-trivial equality proofs that reason about the extensions of guarded recursive constructions. CTT is a variation of Martin-L\\"of type theory in which the identity type is replaced by abstract paths between...

  2. Facts about Type 2

    Medline Plus

    Full Text Available ... Ways to Give Close Are You at Risk? Home Prevention Diagnosing Diabetes and Learning About Prediabetes Type ... To Know Your Risk Alert Day Diabetes Basics Home Symptoms Diagnosis America's Diabetes Challenge Type 1 Type ...

  3. Facts about Type 2

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    Full Text Available ... Type 2 About Us Online Community Meal Planning Sign In Search: Search More Sites Search ≡ Are You ... Your Risk Alert Day Diabetes Basics Home Symptoms Diagnosis America's Diabetes Challenge Type 1 Type 2 Facts ...

  4. Types of Blood Donations

    Science.gov (United States)

    ... Cell Plasma Platelets Red Cells What blood donation type is best for me? **If you do not ... a whole blood donation is recommended** Blood Donation Types: Volunteer Donations The standard or most common type ...

  5. Types of Breast Pumps

    Science.gov (United States)

    ... Health and Consumer Devices Consumer Products Breast Pumps Types of Breast Pumps Share Tweet Linkedin Pin it ... a nipple and used for feeding a baby. Types of Breast Pumps There are three basic types ...

  6. Type 1 diabetes

    Science.gov (United States)

    Insulin-dependent diabetes; Juvenile onset diabetes; Diabetes - type 1; High blood sugar - type 1 diabetes ... Type 1 diabetes can occur at any age. It is most often diagnosed in children, adolescents, or young adults. Insulin is ...

  7. Types of Diabetes

    Science.gov (United States)

    ... Dental Problems Diabetes & Sexual & Urologic Problems What is Diabetes? Diabetes is a disease that occurs when your ... is serious. What are the different types of diabetes? The most common types of diabetes are type ...

  8. Facts about Type 2

    Medline Plus

    Full Text Available ... Forecast® magazine: lp-type-2, In this section Diabetes Basics Type 2 Facts About Type 2 Recently Diagnosed Treatment and Care Blood Glucose Control Complications Medication Doctors, ...

  9. Facts about Type 2

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    Full Text Available ... a Member Donate Now! One Time Monthly In Memory In Honor Become a Member En Español Type 1 Type ... Type 2 Diabetes Risk Test Lower Your Risk Healthy Eating Overweight Smoking High ...

  10. Facts about Type 2

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    Full Text Available ... En Español Type 1 Type 2 About Us Online Community Meal Planning Sign In Search: Search More ... Diagnosing Diabetes and Learning About Prediabetes Type 2 Diabetes Risk Test Lower ...

  11. Facts about Type 2

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    Full Text Available ... Nutrient Content Claims Understanding Carbohydrates Types of Carbohydrates Carbohydrate Counting Make Your Carbs Count Glycemic Index Low-Calorie Sweeteners Sugar and Desserts Fitness Exercise & Type 1 Diabetes Get Started Safely Get And Stay Fit Types ...

  12. Concrete Types for TypeScript

    OpenAIRE

    Richards, Gregor; Zappa Nardelli, Francesco; Vitek, Jan

    2015-01-01

    Typescript extends JavaScript with optional type annotations that are, by design, unsound and, that the Typescript compiler discards as it emits code. This design point preserves programming idioms developers are familiar with, and allows them to leave their legacy code unchanged, while offering a measure of static error checking in parts of the program that have type annotations. We present an alternative design for TypeScript, one where it is possible to support the same degree of dynamism,...

  13. Structural and magnetic characterization of the one-dimensional S = 5/2 antiferromagnetic chain system SrMn(VO4)(OH)

    CERN Document Server

    Sanjeewa, Liurukara D; McGuire, Michael A; McMillen, Colin D; Cao, Huibo; Kolis, Joseph W

    2016-01-01

    The descloizite-type compound, SrMn(VO4)(OH), was synthesized as large single crystals using a high-temperature high-pressure hydrothermal technique. X-ray single crystal structure analysis reveals that the material crystallizes in the acentric orthorhombic space group of P212121. The structure exhibits a one-dimensional feature, with MnO4 chains propagating along the a-axis which are interconnected by VO4 tetrahedra. Raman and infrared spectra were obtained to identify the fundamental vanadate and hydroxide vibrational modes. Magnetization data reveal a broad maximum at approximately 80 K, arising from one-dimensional magnetic correlations with intrachain exchange constant of J/kB = 9.97(3) K between nearest Mn neighbors and a canted antiferromagnetic behavior below TN = 30 K. Single crystal neutron diffraction at 4 K yielded a magnetic structure solution in the lower symmetry of the magnetic space group P21 with two unique chains displaying antiferromagnetically ordered Mn moments oriented nearly perpendicu...

  14. Crystal structures of (Z)-5-[2-(benzo[b]thio-phen-2-yl)-1-(3,5-di-meth-oxy-phen-yl)ethen-yl]-1H-tetra-zole and (Z)-5-[2-(benzo[b]thio-phen-3-yl)-1-(3,4,5-tri-meth-oxy-phen-yl)ethen-yl]-1H-tetra-zole.

    Science.gov (United States)

    Penthala, Narsimha Reddy; Yadlapalli, Jaishankar K B; Parkin, Sean; Crooks, Peter A

    2016-05-01

    (Z)-5-[2-(Benzo[b]thio-phen-2-yl)-1-(3,5-di-meth-oxy-phen-yl)ethen-yl]-1H-tetrazole methanol monosolvate, C19H16N4O2S·CH3OH, (I), was prepared by the reaction of (Z)-3-(benzo[b]thio-phen-2-yl)-2-(3,5-di-meth-oxy-phen-yl)acrylo-nitrile with tri-butyl-tin azide via a [3 + 2]cyclo-addition azide condensation reaction. The structurally related compound (Z)-5-[2-(benzo[b]thio-phen-3-yl)-1-(3,4,5-tri-meth-oxy-phen-yl)ethen-yl]-1H-tetra-zole, C20H18N4O3S, (II), was prepared by the reaction of (Z)-3-(benzo[b]thio-phen-3-yl)-2-(3,4,5-tri-meth-oxy-phen-yl)acrylo-nitrile with tri-butyl-tin azide. Crystals of (I) have two mol-ecules in the asymmetric unit (Z' = 2), whereas crystals of (II) have Z' = 1. The benzo-thio-phene rings in (I) and (II) are almost planar, with r.m.s deviations from the mean plane of 0.0084 and 0.0037 Å in (I) and 0.0084 Å in (II). The tetra-zole rings of (I) and (II) make dihedral angles with the mean planes of the benzo-thio-phene rings of 88.81 (13) and 88.92 (13)° in (I), and 60.94 (6)° in (II). The di-meth-oxy-phenyl and tri-meth-oxy-phenyl rings make dihedral angles with the benzo-thio-phene rings of 23.91 (8) and 24.99 (8)° in (I) and 84.47 (3)° in (II). In both structures, mol-ecules are linked into hydrogen-bonded chains. In (I), these chains involve both tetra-zole and methanol, and are parallel to the b axis. In (II), mol-ecules are linked into chains parallel to the a axis by N-H⋯N hydrogen bonds between adjacent tetra-zole rings.

  15. Types and Automata

    DEFF Research Database (Denmark)

    Schwartzbach, Michael Ignatieff; Meineche Smidt, Erik

    A hierarchical type system for imperative programming languages gives rise to various computational problems, such as type equivalence, type ordering, etc. We present a particular class of finite automata which are shown to be isomorphic to type equations. All the relevant type concepts turn out...... to have well-known automata analogues, such as language equality, language inclusion, etc. This provides optimal or best known algorithms for the type system, by a process of translating type equations to automata, solving the analogous problem, and translating the result back to type equations. Apart...... from suggesting an implementation, this connection lends a certain naturality to our type system. We also introduce a very general form of extended (recursive) type equations which are explained in terms of (monotone) alternating automata. Since types are simply equationally defined trees...

  16. Guarded Cubical Type Theory

    DEFF Research Database (Denmark)

    Birkedal, Lars; Bizjak, Aleš; Clouston, Ranald

    2016-01-01

    types. This further expands the foundations of CTT as a basis for formalisation in mathematics and computer science. We present examples to demonstrate the expressivity of our type theory, all of which have been checked using a prototype type-checker implementation, and present semantics in a presheaf......This paper improves the treatment of equality in guarded dependent type theory (GDTT), by combining it with cubical type theory (CTT). GDTT is an extensional type theory with guarded recursive types, which are useful for building models of program logics, and for programming and reasoning...... with coinductive types. We wish to implement GDTT with decidable type-checking, while still supporting non-trivial equality proofs that reason about the extensions of guarded recursive constructions. CTT is a variation of Martin-L\\"of type theory in which the identity type is replaced by abstract paths between...

  17. Type I Versus Type II Endometrial Cancer

    DEFF Research Database (Denmark)

    Noer, Mette Calundann; Antonsen, Sofie Leisby; Ottesen, Bent

    2018-01-01

    OBJECTIVE: Two distinct types of endometrial carcinoma (EC) with different etiology, tumor characteristics, and prognosis are recognized. We investigated if the prognostic impact of comorbidity varies between these 2 types of EC. Furthermore, we studied if the recently developed ovarian cancer...

  18. Lightening Global Types

    Directory of Open Access Journals (Sweden)

    Tzu-chun Chen

    2014-06-01

    Full Text Available Global session types prevent participants from waiting for never coming messages. Some interactions take place just for the purpose of informing receivers that some message will never arrive or the session is terminated. By decomposing a big global type into several light global types, one can avoid such kind of redundant interactions. Lightening global types gives us cleaner global types, which keep all necessary communications. This work proposes a framework which allows to easily decompose global types into light global types, preserving the interaction sequences of the original ones but for redundant interactions.

  19. Quaternary tin(IV) antimony(III) sulfide decorated with lanthanum(III) ethylenediamine complexes: [La(en)4SbSnS5]2 x 0.5 H2O.

    Science.gov (United States)

    Feng, Mei-Ling; Ye, Dong; Huang, Xiao-Ying

    2009-09-07

    A quaternary tin(IV) antimony(III) sulfide decorated by lanthanum(III) ethylenediamine complexes, namely, [La(en)(4)SbSnS(5)](2) x 0.5 H(2)O (1; en = ethylenediamine), has been solvothermally synthesized and structurally, thermally, and optically characterized. Its structure features an isolated hexanuclear molecule of [La(en)(4)SbSnS(5)](2). The intermolecule hydrogen-bond interactions result in a three-dimensional supramolecular network, which remains intact upon dehydration.

  20. Verification of the computer code ATHLET in the framework of the external verification group ATHLET BETHSY test 5.2c - total loss of feedwater. Final report; Verifikation des ATHLET-Rechenprogramms im Rahmen der externen Verifikationsgruppe ATHLET BETHSY Test 5.2c - Totalverlust des Speisewassers. Abschlussbericht

    Energy Technology Data Exchange (ETDEWEB)

    Krepper, E.; Schaefer, F. [Forschungszentrum Rossendorf e.V. (FZR) (Germany). Inst. fuer Sicherheitsforschung

    1998-08-01

    In the framework of the external validation of the thermohydraulic code ATHLET Mod 1.1 Cycle D, which has been developed by the GRS, post test analyses of two experiments were done, which were performed at the French integral test facility BETHSY. The BETHSY experiment 5.2c investigates the accident procedures in case of a total loss of feedwater at the steam generator secondary side. In such an accident the emergency cooling of the reactor core with primary bleed and feed, the behaviour of the steam generators in case of dry out and the long time behaviour of the test facility are special subjects of interest. During the experiment the high pressure injection system, the hydroaccumulators and the low pressure injection system were available. The evaluation of the calculated results shows, that all main phenomena can be calculated in a good quality compared with the experiment. Resulting from various calculations it should be noticed that the quality of the results strongly depends on the modelling of the heat losses of the facility, which were partly compensated by the trace heating. This trace heating was changed several times in the experiment to compensate the changing heat losses. The exact modelling of the resulting heat losses has a strong influence on the course of the whole transient. In this test the unsufficient modelling of the resulting heat losses may be the reason for deviations of the calculated transient from the observed transient. The results shows, that the safety relevant statement of the experiment could be reproduced by the code ATHLET. (orig.) [Deutsch] Im Rahmen der externen Validierung des von der Gesellschaft fuer Anlagen- und Reaktorsicherheit entwickelten Stoerfallcodes ATHLET, der in der Version Mod 1.1 Cycle D vorlag, wurden zwei Experimente nachgerechnet und analysiert, die an der franzoesischen Versuchsanlage BETHSY durchgefuehrt wurden. Das Experiment 5.2c dient der Untersuchung der Notfallprozeduren beim Totalausfall der

  1. Classifying carcinogenic substances for the limitation of emission concentrations according to no. 5.2.7.1.1 of TA Luft amendment (draft); Klassierung krebserzeugender Stoffe zur Begrenzung der Massenkonzentration im Abgas nach der Nr. 5.2.7.1.1 der TA Luft-Novelle (Entwurf)

    Energy Technology Data Exchange (ETDEWEB)

    Schneider, K.; Schuhmacher-Wolz, U.; Oltmanns, J.; Hassauer, M. [FoBiG Forschungs- und Beratungsinstitut Gefahrstoffe GmbH, Freiburg im Breisgau (Germany)

    2002-07-01

    In the German Ordinance TA Luft carcinogenic substances are assigned to three classes with differing maximum emission concentrations. Assignment is according to the carcinogenic potency of the relevant substances (acryl amide, acrylonitrile, arsenic, benzene, bromoethane, 1,3-butadiene, cadmium, chromium, cobalt, 1,2-dichloroethane, dinitrotoluenes, ethylene oxide, asbestos, man-made mineral fibres, nickel, o-toluidine, propylene oxide, pyrolysis products, styrene oxide, trichloroethylene, vinyl chloride, 4-vinyl-1,2-cyclohexene diepoxide, antimony trioxide, crystalline silicium dioxide, butanone oxime). After developing a methodological approach proposals for the assignment of the substances to emission classes have been worked out and discussed in a scientific working group. The classifications and the underlying rationales have been documented in monographs. For the assessment of carcinogenic potency published unit risk estimates have been used or, if not available, derived within the project. Cancer potency estimates have been scrutinized in relation to their quality. Using unit risk estimates 16 out of 23 substances could be evaluated according to their potency and have been assigned to the respective emission class in No. 5.2.7.1.1, TA Luft (draft). In case of 7 substances without reliable potency estimates screening methods (T25, CEL{sub min}), allowing only a rough consideration of cancer potency in the higher dose range have been applied to come to a preliminary assignment to emission classes. For man-made mineral fibres a potency consideration in relation to asbestos fibres has been carried out. (orig.) [German] Krebserzeugende Stoffe werden in der novellierten TA Luft (Entwurf) in drei Klassen mit jeweils unteschiedlichen maximalen Emissions-Massenkonzentrationen eingeordnet. Diese Zuordnung erfolgte unter Beruecksichtigung der kanzerogenen Wirkstaerke der betrachteten emissionsrelevanten Stoffe (Acrylamid, Acrylnitril, Arsen, Benzol, Bromethan, 1

  2. Tectonic interpretation of the source of the 2011 M{sub w} 5.2 Lorca earthquake and its surface effects; Interpretacion tectonica de la fuente del terremoto de Lorca de 2011 (M{sub w} 5,2) y sus efectos superficiales

    Energy Technology Data Exchange (ETDEWEB)

    Martinez-Diaz, J. J.; Alvarez-Gomez, J. A.; Garcia-Mayordomo, J.; Insua-Arevalo, J. M.; Martinez-Gonzalez, F.; Rodriguez-Peces, M. J.

    2012-11-01

    On 11 May 2011 a 5.2 M{sub w} earthquake struck the city of Lorca (south-east Spain), causing huge damage. The aim of this paper is to analyse and interpret the geological source of the earthquake in order to explain its location, size and surface effects. We have studied in detail the tectonic structure of the epicentral region, the spatial distribution of the seismic sequence and the distribution and characteristics of the damage and earthquake-triggered debris and rock falls. Combining all this information we provide a synoptic view of the genesis and the effects of the earthquake and discuss the implications of this event in the context of the seismic hazard of the adjacent Alhama de Murcia fault (FAM) segments according to Coulomb failure stress modelling. The seismotectonic characteristics of the earthquake, the local structure of the epicentral area, and the location and amount of surface deformation are consistent with the asymmetric (southward propagating) rupture of a section of the FAM up to 7 km in length. Nevertheless, most of the energy was released in a complex structure coinciding with the Matalauva duplex located to the SW of the hypocentre. This rupture produced a pulse of NW-SE strong ground motion (normal to the FAM), with its maximum amplitude located to the south-west of the seismic sequence. This explains the directionality effects observed in the distribution of the rock-falls and building damage. The concentration of the worst of the damage on the northern slopes of the Sierra de la Pena Rubia is consistent with this seismotectonic scenario. (Author) 50 refs.

  3. Type checking with open type functions

    DEFF Research Database (Denmark)

    Schrijvers, Tom; Jones, Simon Peyton; Chakravarty, Manual

    2008-01-01

    We report on an extension of Haskell with open type-level functions and equality constraints that unifies earlier work on GADTs, functional dependencies, and associated types. The contribution of the paper is that we identify and characterise the key technical challenge of entailment checking......; and we give a novel, decidable, sound, and complete algorithm to solve it, together with some practically-important variants. Our system is implemented in GHC, and is already in active use....

  4. Type Systems for Bigraphs

    DEFF Research Database (Denmark)

    Elsborg, Ebbe; Hildebrandt, Thomas; Sangiorgi, Davide

    We propose a novel and uniform approach to type systems for (process) calculi, which roughly pushes the challenge of designing type systems and proving properties about them to the meta-model of bigraphs. Concretely, we propose to define type systems for the term language for bigraphs, which...... of controls and a set of reaction rules, collectively a bigraphical reactive system (BRS). Possible advantages of developing bigraphical type systems include: a deeper understanding of a type system itself and its properties; transfer of the type systems to the concrete family of calculi that the BRS models......; and the possibility of modularly adapting the type systems to extensions of the BRS (with new controls). As proof of concept we present a model of a pi-calculus, develop an i/o-type system with subtyping on this model, prove crucial properties (including subject reduction) for this type system, and transfer...

  5. Multiparty Asynchronous Session Types

    DEFF Research Database (Denmark)

    Honda, Kohei; Yoshida, Nobuko; Carbone, Marco

    2016-01-01

    . This work extends the foregoing theories of binary session types to multiparty, asynchronous sessions, which often arise in practical communication-centered applications. Presented as a typed calculus for mobile processes, the theory introduces a new notion of types in which interactions involving multiple......Communication is a central elements in software development. As a potential typed foundation for structured communication-centered programming, session types have been studied over the past decade for a wide range of process calculi and programming languages, focusing on binary (two-party) sessions...... peers are directly abstracted as a global scenario. Global types retain the friendly type syntax of binary session types while specifying dependencies and capturing complex causal chains of multiparty asynchronous interactions. A global type plays the role of a shared agreement among communication peers...

  6. Mapping of the proton drip-line up to Z = 20: Observation of the T Z = - {5}/{2} series 23Si, 27S, 31Ar and 35Ca

    Science.gov (United States)

    Langevin, M.; Mueller, A. C.; Guillemaud-Mueller, D.; Saint-Laurent, M. G.; Anne, R.; Bernas, M.; Galin, J.; Guerreau, D.; Jacmart, J. C.; Hoath, S. D.; Naulin, F.; Pougheon, F.; Quiniou, E.; Détraz, C.

    1986-07-01

    The series of four T Z = - {5}/{2} nuclei, 23Si, 27S, 31Ar and 35Ca, predicted to be bound or nearly bound against one- or two-proton emission is observed. The experimental evidence comes from direct identification of the magnetically separated products from interactions of 77 {MeV}/{u}40Ca projectiles with a nickel target.

  7. Investigations of neutron-rich nuclei at the dripline through their analogue states : The cases of $^{10}$Li - $^{10}$Be (T=2) and $^{17}$C - $^{17}$N (T=5/2)

    CERN Multimedia

    2002-01-01

    We propose to study the elastic resonance scattering reactions $^{9}$Li+p and $^{16}$C+p to investigate the energies, spins and parities of the lowest T=2 states in $^{10}$Be and the T=5/2 states in $^{17}$N. These are analogue states of the ground states and first excited states in $^{10}$Li and $^{17}$C.

  8. 2-Amino-N-{4-[5-(2-phenanthrenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]-phenyl} Acetamide (OSU-03012), a Celecoxib Derivative, Directly Targets p21-Activated Kinase

    National Research Council Canada - National Science Library

    Leonardo M. Porchia; Marcy Guerra; Yu-Chieh Wang; Yunlong Zhang; Allan V. Espinosa; Motoo Shinohara; Samuel K. Kulp; Lawrence S. Kirschner; Motoyasu Saji; Ching-Shih Chen; Matthew D. Ringel

    2007-01-01

    ...). We hypothesized that reduced PAK activity was involved in the effects of 2-amino- N -{4-[5-(2-phenanthrenyl)-3-(trifluoromethyl)-1 H -pyrazol-1-yl]-phenyl} acetamide (OSU-03012), a previously characterized PDK1 inhibitor derived from celecoxib...

  9. The effects of structural and microenvironmental disorder on the electronic properties of poly[2-methoxy,5-(2 '-ethyl-hexoxy)-1,4-phenylene vinylene] (MEH-PPV) and related oligomers

    NARCIS (Netherlands)

    Wachsmann-Hogiu, S; Peteanu, LA; Liu, LA; Yaron, DJ; Wildeman, J

    2003-01-01

    In this study, electroabsorption (Stark) spectroscopy is used to determine the trace of the change in polarizability (tr (Delta x) over bar) and the absolute value of the change in dipole moment (/Delta(mu) over right arrow/) of the electroluminescent polymer poly [2-methoxy,5-(2'-ethyl-hexoxy)-

  10. Synthesis of some novel 4-aza-tricyclo[5.2.2.0 2,6 ]undecane-3,5,8-triones from 2-trimethylsilyloxy-1,3-cyclohexadiene and 1-methoxy-1,3-cyclohexadiene

    Directory of Open Access Journals (Sweden)

    Hosapalya Thimmaiah Srinivasa

    2012-01-01

    Full Text Available The synthesis and characterization of nine novel Diels-Alder cycloadducts: the 4-aza-tricyclo[5.2.2.0 2,6] undecane-3,5,8-triones using 2-trimethylsilyloxy-1,3-cyclohexadiene and 1-methoxy-1,3-cyclohexadiene is reported. The isolated yields of the pure cycloadducts range between 75 to 95%.

  11. Rhodium-catalyzed [5 + 2 + 1] cycloaddition of ene-vinylcyclopropanes and CO: reaction design, development, application in natural product synthesis, and inspiration for developing new reactions for synthesis of eight-membered carbocycles.

    Science.gov (United States)

    Wang, Yi; Yu, Zhi-Xiang

    2015-08-18

    Practical syntheses of natural products and their analogues with eight-membered carbocyclic skeletons are important for medicinal and biological investigations. However, methods and strategies to construct the eight-membered carbocycles are limited. Therefore, developing new methods to synthesize the eight-membered carbocycles is highly desired. In this Account, we describe our development of three rhodium-catalyzed cycloadditions for the construction of the eight-membered carbocycles, which have great potential in addressing the challenges in the synthesis of medium-sized ring systems. The first reaction described in this Account is our computationally designed rhodium-catalyzed two-component [5 + 2 + 1] cycloaddition of ene-vinylcyclopropanes (ene-VCPs) and CO for the diastereoselective construction of bi- and tricyclic cyclooctenones. The design of this reaction is based on the hypothesis that the C(sp(3))-C(sp(3)) reductive elimination of the eight-membered rhodacycle intermediate generated from the rhodium-catalyzed cyclopropane cleavage and alkene insertion, giving Wender's [5 + 2] cycloadduct, is not easy. Under CO atmosphere, CO insertion may occur rapidly, converting the eight-membered rhodacycle into a nine-membered rhodacycle, which then undergoes an easy C(sp(2))-C(sp(3)) reductive elimination process and furnishes the [5 + 2 + 1] product. This hypothesis was supported by our preliminary DFT studies and also served as inspiration for the development of two [7 + 1] cycloadditions: the [7 + 1] cycloaddition of buta-1,3-dienylcyclopropanes (BDCPs) and CO for the construction of cyclooctadienones, and the benzo/[7 + 1] cycloaddition of cyclopropyl-benzocyclobutenes (CP-BCBs) and CO to synthesize the benzocyclooctenones. The efficiency of these rhodium-catalyzed cycloadditions can be revealed by the application in natural product synthesis. Two eight-membered ring-containing natural products, (±)-asterisca-3(15),6-diene and (+)-asteriscanolide, have been

  12. Facts about Type 2

    Medline Plus

    Full Text Available ... Index Low-Calorie Sweeteners Sugar and Desserts Fitness Exercise & Type 1 Diabetes Get Started Safely Get And Stay Fit Types of Activity Weight Loss Assess Your Lifestyle Getting Started Food Choices In ...

  13. Facts about Type 2

    Medline Plus

    Full Text Available ... Student Resources History of Diabetes Resources for School Projects How to Reference Our Site Diabetes Basics Myths ... to later on. Some groups have a higher risk for developing type 2 diabetes than others. Type ...

  14. Types of Dementia

    Science.gov (United States)

    ... A A Share Plus on Google Plus Alzheimer's & Dementia alz.org | IHaveAlz Overview What Is Dementia Types ... local chapter Join our online community Types of Dementia Dementia is a general term for loss of ...

  15. Facts about Type 2

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    Full Text Available ... Nutrient Content Claims Understanding Carbohydrates Types of Carbohydrates Carbohydrate Counting Make Your Carbs Count Glycemic Index Low-Calorie Sweeteners Sugar and Desserts Fitness Exercise & Type 1 Diabetes Get Started Safely Get And ...

  16. Facts about Type 2

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    Full Text Available ... Professional Books Patient Access to Research Student Resources History of Diabetes Resources for School Projects How to Reference ... Basics Symptoms Type 1 Type 2 Gestational Myths Statistics Common ... of Events Local Offices Volunteer Opportunities Signature Events Camps ...

  17. Facts about Type 2

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    Full Text Available ... Living with Diabetes Home Recently Diagnosed Where Do I Begin With Type2? Living With Type 1 Diabetes ... Heart-Healthy Foods Holiday Meal Planning What Can I Eat? Making Healthy Food Choices Diabetes Superfoods Non- ...

  18. Facts about Type 2

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    Full Text Available ... Enroll in the Living WIth Type 2 Diabetes Program Gestational What is Gestational Diabetes? How to Treat ... Enroll in the Living WIth Type 2 Diabetes Program In It Together We Can Help Center for ...

  19. Facts about Type 2

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    Full Text Available ... Your Risk Risk Test Alert Day Prediabetes My Health Advisor Tools to Know Your Risk Diabetes Basics Symptoms Type 1 Type 2 Gestational Myths Statistics Common Terms Genetics Living With Diabetes ...

  20. Types of Ulcerative Colitis

    Science.gov (United States)

    ... Colitis? > Types of Ulcerative Colitis Types of Ulcerative Colitis Email Print + Share If you are diagnosed with ... abdomen may occur in active disease. Left-sided Colitis Continuous inflammation that begins at the rectum and ...

  1. Facts about Type 2

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    Full Text Available ... Medicaid & CHIP For Parents & Kids Safe at School Everyday Life Children and Type 2 Diabetes Know Your ... Index Low-Calorie Sweeteners Sugar and Desserts Fitness Exercise & Type 1 Diabetes Get Started Safely Get And ...

  2. Types of Anesthesia

    Science.gov (United States)

    ... to Your Parents - or Other Adults Types of Anesthesia KidsHealth > For Teens > Types of Anesthesia Print A ... I Get? en español Tipos de anestesia About Anesthesia Anesthesia is broken down into three main categories: ...

  3. Facts about Type 2

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    Full Text Available ... Know Your Risk Alert Day Diabetes Basics Home Symptoms Diagnosis America's Diabetes Challenge Type 1 Type 2 Facts ... Online Community Site Menu Are You at Risk? Diagnosis Lower Your Risk Risk Test Alert Day Prediabetes ...

  4. Facts about Type 2

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    Full Text Available ... Americans/Pacific Islanders, as well as the aged population. Patient Education Materials — Taking Care of Type 2 ... 1 Type 2 Gestational Myths Statistics Common Terms Genetics Living With Diabetes Recently Diagnosed Treatment & Care Complications ...

  5. Preventing Type 2 Diabetes

    Science.gov (United States)

    ... Problems Diabetes & Sexual & Urologic Problems Preventing Type 2 Diabetes Perhaps you have learned that you have a ... I lower my chances of developing type 2 diabetes? Research such as the Diabetes Prevention Program shows ...

  6. Facts about Type 2

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    Full Text Available ... Fit Types of Activity Weight Loss Assess Your Lifestyle Getting Started Food Choices In My Community Home ... glucose levels normal. Type 2 is treated with lifestyle changes, oral medications (pills), and insulin. When glucose ...

  7. Facts about Type 2

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    Full Text Available ... People Working to Stop Diabetes Common Terms Diabetes Statistics Infographics Living with Diabetes Home Recently Diagnosed Where ... Basics Symptoms Type 1 Type 2 Gestational Myths Statistics Common Terms Genetics Living With Diabetes Recently Diagnosed ...

  8. Facts about Type 2

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    Full Text Available ... to Know Your Risk Diabetes Basics Symptoms Type 1 Type 2 Gestational Myths Statistics Common Terms Genetics Living With Diabetes Recently Diagnosed Treatment & Care Complications Health Insurance For Parents & Kids Know ...

  9. Type 1 Diabetes

    Science.gov (United States)

    ... develop in adults. Despite active research, type 1 diabetes has no cure. Treatment focuses on managing blood sugar levels with insulin, diet and lifestyle to prevent complications. Symptoms Type 1 diabetes signs and symptoms can appear relatively suddenly and ...

  10. Facts about Type 2

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    Full Text Available ... diagnosed. Diabetes causes more deaths a year than breast cancer and AIDS combined. Your gift today will help ... Basics Symptoms Type 1 Type 2 Gestational Myths Statistics Common Terms Genetics Living With Diabetes Recently Diagnosed ...

  11. Type 2 diabetes

    Science.gov (United States)

    ... diabetes; Oral hypoglycemic - type 2 diabetes; High blood sugar - type 2 diabetes ... mmol/L) 2 hours after drinking a special sugar drink. Diabetes screening is recommended for: Overweight children who have ...

  12. Different Types of Lupus

    Science.gov (United States)

    ... Twitter Facebook Pinterest Email Print Different types of lupus Lupus Foundation of America September 18, 2017 Resource ... lupus. Learn more about each type below. Systemic lupus erythematosus Systemic lupus is the most common form ...

  13. Types of Stem Cells

    Science.gov (United States)

    ... Stem Cell Glossary Search Toggle Nav Types of Stem Cells Stem cells are the foundation from which all ... Learn About Stem Cells > Types of Stem Cells Stem cells Stem cells are the foundation for every organ ...

  14. Facts about Type 2

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    Full Text Available ... Español Type 1 Type 2 About Us Online Community Meal Planning Sign In Search: Search More Sites ... Basics Living with Diabetes Food & Fitness In My Community Advocacy Research & Practice Ways to Give Close Are ...

  15. Unlocking Personality Type.

    Science.gov (United States)

    Tieger, Paul D.

    2002-01-01

    This article examines some of the intricacies of personality types and their effect on career choices. Proposes that knowing students' Myers-Briggs personality types can help school counselors guide them down the right career path. (GCP)

  16. Dynamically typed languages

    OpenAIRE

    Tratt, Laurence

    2009-01-01

    Dynamically typed languages such as Python and Ruby have experienced a rapid grown in popularity in recent times. However, there is much confusion as to what makes these languages interesting relative to statically typed languages, and little knowledge of their rich history. In this chapter I explore the general topic of dynamically typed languages, how they differ from statically typed languages, their history, and their defining features.

  17. Diabetes, Type 1

    OpenAIRE

    Riazi, Afsane; Bradley, Clare

    2000-01-01

    This chapter provides an overview of the role of psychological stress in Type 1 diabetes. Studies relating to stress and Type 1 diabetes onset and control, as well as the evidence relating to stress management training in people with Type 1 diabetes are discussed.

  18. Diabetes Type 2

    Science.gov (United States)

    Diabetes means your blood glucose, or blood sugar, levels are too high. With type 2 diabetes, the more common type, your body does not ... You have a higher risk of type 2 diabetes if you are older, have obesity, have a ...

  19. Facts about Type 2

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    Full Text Available ... Your Risk Diabetes Basics Symptoms Type 1 Type 2 Gestational Myths Statistics Common Terms Genetics Living With Diabetes Recently Diagnosed Treatment & Care Complications Health Insurance For Parents & Kids Know Your ... Type 2 Diabetes Program Food & Fitness Food Recipes Planning Meals ...

  20. Type 1 Diabetes Facts

    Science.gov (United States)

    ... Contact Us Donate Events More Type 1 Diabetes Facts Type 1 diabetes (T1D) is an autoimmune disease ... of T1D The Complexity of Diagnosing T1D T1D Facts Insulin Types and Usage T1D Treatments Sign up ...

  1. Facts about Type 2

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    Full Text Available ... Home Prevention Diagnosing Diabetes and Learning About Prediabetes Type 2 Diabetes Risk Test Lower Your Risk Healthy Eating Overweight ... About Type 2 Enroll in the Living WIth Type 2 Diabetes Program Gestational What is Gestational Diabetes? How to ...

  2. Osteogenesis imperfecta type V

    DEFF Research Database (Denmark)

    Rauch, Frank; Moffatt, Pierre; Cheung, Moira

    2013-01-01

    Osteogenesis imperfecta (OI) type V is an autosomal dominant bone fragility disorder that we had described a decade ago. Recent research has shown that OI type V is caused by a recurrent c.-14C>T mutation in IFITM5. In the present study, we assessed all patients diagnosed with OI type V at our in...

  3. Tension Type Headache: Evaluation of Chronic Type

    Directory of Open Access Journals (Sweden)

    Ömer Karadaş

    2013-11-01

    Full Text Available Tension type headache(TTH which is a primary headache has episodic and chronic forms. Episodic TTH (ETTH can also be frequent-type and non-frequent-type. According to population-based studies, annual prevalence rates are 38.3% for ETTH and 2.2% for chronic TTH (CTTH. Patients can shift between the sub-groups of TTH. In particular, patients with ETTH are at risk of developing CTTH. Peripheral and central nociceptive mechanism are thought to be responsible in occurrence of TTH. Psychiatric disorders are frequently associated with TTH. Although basic and combined analgesics are used in acute treatment and antidepresants are used in prophylaxis, new treatment modalities are needed.

  4. Improving Precision of Types

    DEFF Research Database (Denmark)

    Winther, Johnni

    mixing of unrelated types. Secondly, we present an improvement of the type checking algorithm in Java which enables the compiler to detect and ease the use of a common programming idiom called guarded casts. Thirdly, we present an improvement of the precision with which classes generated by a parser......Types in programming languages provide a powerful tool for the programmer to document the code so that a large aspect of the intent can not only be presented to fellow programmers but also be checked automatically by compilers. The precision with which types model the behavior of programs...... is crucial to the quality of these automated checks, and in this thesis we present three different improvements to the precision of types in three different aspects of the Java programming language. First we show how to extend the type system in Java with a new type which enables the detection of unintended...

  5. Instant HTMl5 2D platformer

    CERN Document Server

    Temple, Aidan

    2013-01-01

    Filled with practical, step-by-step instructions and clear explanations for the most important and useful tasks. The step-by-step approach taken by this book will show you how to develop a 2D HTML5 platformer-based game that you will be able to publish to multiple devices.This book is great for anyone who has an interest in HTML5 games development, and who already has a basic to intermediate grasp on both the HTML markup and JavaScript programming languages. Therefore, due to this requirement, the book will not discuss the inner workings of either of these languages but will instead attempt to

  6. Implementing VMware Horizon View 5.2

    CERN Document Server

    Ventresco, Jason

    2013-01-01

    A step-by-step tutorial covering all components of the View Horizon suite in detail, to ensure that you can utilize all features of the platform, and discover all of the possible ways that it can be used within your own environment.If you are a newcomer in system administration, and you wish to implement a small to midsized Horizon View environment, then this book is for you. It will also benefit individuals who wish to administrate and manage Horizon View more efficiently or are studying for the VCP5-DT.

  7. 42 CFR 5.2 - Definitions.

    Science.gov (United States)

    2010-10-01

    ... health services to inmates in a U.S. penal or correctional institution (under section 323 of the Act) or a State correctional institution; (5) a Public Health Service medical facility (used in connection... and any other officer or employee of the Department to whom the authority involved has been delegated...

  8. D5.2 Numerical tools

    DEFF Research Database (Denmark)

    Møhlenberg, Flemming; Christensen, Erik Damgaard

    2015-01-01

    . The planning and design of MUPS in MERMAID has therefore not only involved standard engineering methods, but also advanced numerical tools, that can enable a detailed understanding of the environment and the interactions between the MUP and the surrounding water environments. The intention of this report...... is to summarise the advanced methods developed and used during MERMAID to support the planning and design of MUP’s and form a guideline and inspiration to planners on how to meet the challenges that turns up during design of such structures....

  9. 29 CFR 5.2 - Definitions.

    Science.gov (United States)

    2010-07-01

    ... pits, job headquarters, tool yards, etc., of a commercial or material supplier, which are established by a supplier of materials for the project before opening of bids and not on the site of the work as... guarantees from the United States is employed regardless of any contractual relationship alleged to exist...

  10. Synthesis of 2-(5-Nitropyrid-2-yl-3-(4-substitutedphenylaminoisoxazol-5(2H-ones and Their Rearrangements to Imidazo[1,2-a]- pyridines and Indoles with Triethylamine

    Directory of Open Access Journals (Sweden)

    K. Akbari Dilmaghani

    2002-12-01

    Full Text Available 3-(4-Substitutedphenylaminoisoxazol-5(2H-ones, substituted on nitrogen with a nitropyridine group, react with triethylamine to give imidazo[1,2-a]pyridines and indoles. With 4-bromophenyl and 4-methylphenyl group substituents only imidazopyridines are formed, but the 4-methoxyphenyl derivative gave a 3:1 mixture of the corresponding imidazo[1,2-a]pyridine and 2-pyridylaminoindole, respectively.

  11. The dominance of the ν(0d5/2) 2 configuration in the N = 8 shell in 12Be from the breakup reaction on a proton target at intermediate energy

    Science.gov (United States)

    Chung, Le Xuan; Bertulani, Carlos A.; Egelhof, Peter; Ilieva, Stoyanka; Khoa, Dao T.; Kiselev, Oleg A.

    2017-11-01

    The momentum distribution of 11Be fragments produced by the breakup of 12Be interacting with a proton target at 700.5 MeV/u energy has been measured at GSI Darmstadt. To obtain the structure information on the anomaly of the N = 8 neutron shell, the momentum distribution of 11Be fragments from the one-neutron knockout 12Be (p , pn) reaction, measured in inverse kinematics, has been analysed in the distorted wave impulse approximation (DWIA) based on a quasi-free scattering scenario. The DWIA analysis shows a surprisingly strong contribution of the neutron 0d5/2 orbital in 12Be to the transverse momentum distribution of the 11Be fragments. The single-neutron 0d5/2 spectroscopic factor deduced from the present knock-out data is 1.39(10), which is significantly larger than that deduced recently from data of 12Be breakup on a carbon target. This result provides a strong experimental evidence for the dominance of the neutron ν(0d5/2) 2 configuration in the ground state of 12Be.

  12. Guarded Type Promotion

    DEFF Research Database (Denmark)

    Winther, Johnni

    2011-01-01

    In Java, explicit casts are ubiquitous since they bridge the gap between compile-time and runtime type safety. Since casts potentially throw a ClassCastException, many programmers use a defensive programming style of guarded casts. In this programming style casts are protected by a preceding...... in a Java 6 compiler. Through our extensive testing of real-life code we show that guarded casts account for approximately one fourth of all casts and that Guarded Type Promotion can eliminate the need for 95 percent of these guarded casts....... conditional using the instanceof operator and thus the cast type is redundantly mentioned twice. We propose a new typing rule for Java called Guarded Type Promotion aimed at eliminating the need for the explicit casts when guarded. This new typing rule is backward compatible and has been fully implemented...

  13. Types of biological variables.

    Science.gov (United States)

    Mayya, Shreemathi S; Monteiro, Ashma D; Ganapathy, Sachit

    2017-06-01

    Identification and description of variables used in any study is a necessary component in biomedical research. Statistical analyses rely on the type of variables that are involved in the study. In this short article, we introduce the different types of biological variables. A researcher has to be familiar with the type of variable he/she is dealing with in his/her research to decide about appropriate graphs/diagrams, summary measures and statistical analysis.

  14. Mastering TypeScript

    CERN Document Server

    Rozentals, Nathan

    2015-01-01

    Whether you are a JavaScript developer aiming to learn TypeScript, or an experienced TypeScript developer wanting to take your skills to the next level, this book is for you. From basic to advanced language constructs, test-driven development, and object-oriented techniques, you will learn how to get the most out of the TypeScript language.

  15. Type II universal spacetimes

    Science.gov (United States)

    Hervik, S.; Málek, T.; Pravda, V.; Pravdová, A.

    2015-12-01

    We study type II universal metrics of the Lorentzian signature. These metrics simultaneously solve vacuum field equations of all theories of gravitation with the Lagrangian being a polynomial curvature invariant constructed from the metric, the Riemann tensor and its covariant derivatives of an arbitrary order. We provide examples of type II universal metrics for all composite number dimensions. On the other hand, we have no examples for prime number dimensions and we prove the non-existence of type II universal spacetimes in five dimensions. We also present type II vacuum solutions of selected classes of gravitational theories, such as Lovelock, quadratic and L({{Riemann}}) gravities.

  16. TypeScript revealed

    CERN Document Server

    Maharry, Dan

    2013-01-01

    TypeScript Revealed is a quick 100-page guide to Anders Hejlsberg's new take on JavaScript. With this brief, fast-paced introduction to TypeScript, .NET, Web and Windows 8 application developers who are already familiar with JavaScript will easily get up to speed with TypeScript and decide whether or not to start incorporating it into their own development. TypeScript is 'JavaScript for Application-scale development'; a superset of JavaScript that brings to it an additional object-oriented-like syntax familiar to .NET programmers that compiles down into simple, clean JavaScript that any browse

  17. Facts about Type 2

    Medline Plus

    Full Text Available ... Nutrient Content Claims Understanding Carbohydrates Types of Carbohydrates Carbohydrate Counting Make Your Carbs Count Glycemic Index Low-Calorie Sweeteners Sugar and Desserts Fitness Exercise & ...

  18. Facts about Type 2

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    Full Text Available ... most common form of diabetes. In type 2 diabetes, your body does not use insulin properly. This is called ... Help Enroll in the Living WIth Type 2 Diabetes Program Food & Fitness Food Recipes Planning Meals What Can I Eat Weight Loss Fitness In My Community Calendar of Events ...

  19. Facts about Type 2

    Medline Plus

    Full Text Available ... Diabetes This two-page introduction to type 2 diabetes is in PDF format so you can download it, print it, and hand it out to patients. You can also download the Spanish version. Last Reviewed: ... magazine: lp-type-2, . In this section ...

  20. Facts about Type 2

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    Full Text Available ... Type 2 Diabetes Program donate en -- #GiveForDiabetes - givefordiabetes.html #GiveForDiabetes Every 21 seconds, someone is diagnosed with ... Donate Today We Can Help - we-can-help.html Chat Online Chat Closed engagement en -- Free Type ...

  1. Facts about Type 2

    Medline Plus

    Full Text Available Donate Today! Become a Member Donate Now! One Time Monthly In Memory In Honor Become a Member En Español Type 1 Type 2 About Us ... Month® American Diabetes Association Alert Day® Become a Member Advocacy Home Take Action Advocacy Priorities 2018 State ...

  2. Facts about Type 2

    Medline Plus

    Full Text Available ... Americans/Pacific Islanders, as well as the aged population. Patient Education Materials — Taking Care of Type 2 Diabetes This two-page introduction to type 2 diabetes is in PDF format so you can download it, print it, ...

  3. Facts about Type 2

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    Full Text Available ... Research Leaders World's Largest Diabetes Meeting Recent Advances Type 1 Research Highlights Research Excellence Honorees How We Fund Research ... steps you take Help change the conversation about type 2 diabetes. ... With Us Register for diabetes news, research and food & fitness tips. Email: Sign Up Thank ...

  4. Facts about Type 2

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    Full Text Available ... Membership Please Join Us in the Fight for a Cure Your tax-deductible gift today can fund ... A A Listen En Español Facts About Type 2 Type 2 diabetes is the most common form ...

  5. Facts about Type 2

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    Full Text Available ... 2383) Give by Mail Close www.diabetes.org > Diabetes Basics > Type 2 Share: Print Page Text Size: A A A ... 2 diabetes is the most common form of diabetes. In type 2 diabetes, your body does not use insulin properly. ...

  6. Facts about Type 2

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    Full Text Available ... blood glucose levels may hurt your eyes, kidneys, nerves or heart. Some people with type 2 can ... type 2 diabetes. Shopdiabetes.org: Your Stress-Free System for Family Dinners! - 2017-03-book-oclock-scramble. ...

  7. Flash-Type Discrimination

    Science.gov (United States)

    Koshak, William J.

    2010-01-01

    This viewgraph presentation describes the significant progress made in the flash-type discrimination algorithm development. The contents include: 1) Highlights of Progress for GLM-R3 Flash-Type discrimination Algorithm Development; 2) Maximum Group Area (MGA) Data; 3) Retrieval Errors from Simulations; and 4) Preliminary Global-scale Retrieval.

  8. Diabetes Type 1

    Science.gov (United States)

    Diabetes means your blood glucose, or blood sugar, levels are too high. With type 1 diabetes, your pancreas does not make insulin. Insulin is ... kidneys, nerves, and gums and teeth. Type 1 diabetes happens most often in children and young adults ...

  9. Beyond Type D personality

    DEFF Research Database (Denmark)

    Pelle, Aline J; Pedersen, Susanne S.; Szabó, Balázs M

    2009-01-01

    Type D personality has been associated with impaired health status in chronic heart failure (CHF), but other psychological factors may also be important.......Type D personality has been associated with impaired health status in chronic heart failure (CHF), but other psychological factors may also be important....

  10. Types of Foreign Aid

    DEFF Research Database (Denmark)

    Bjørnskov, Christian

    Foreign aid is given for many purposes and different intentions, yet most studies treat aid flows as a unitary concept. This paper uses factor analysis to separate aid flows into different types. The main types can be interpreted as aid for economic purposes, social purposes, and reconstruction...

  11. Facts about Type 2

    Medline Plus

    Full Text Available ... Count Glycemic Index Low-Calorie Sweeteners Sugar and Desserts Fitness Exercise & Type 1 Diabetes Get Started Safely Get And Stay Fit Types of Activity Weight Loss Assess Your Lifestyle Getting Started Food Choices In My Community Home Find Your Local ...

  12. Facts about Type 2

    Medline Plus

    Full Text Available Donate Today! Become a Member Donate Now! One Time Monthly In Memory In Honor Become a Member En Español Type 1 Type 2 About Us ... Month® American Diabetes Association Alert Day® Become a Member Advocacy Home Take Action Advocacy Priorities State Priorities ...

  13. Typing polymorphic recursion

    OpenAIRE

    Figueiredo, Lucília Camarão de; Camarão, Carlos

    2001-01-01

    This paper discusses some advantages of supporting polymorphic recursión in programming languages and describes a decidable type inference algorithm for typing polymorphic and possibly mutually recursive definitions, using Haskell to provide an executable high level specification of the algorithm.

  14. Facts about Type 2

    Medline Plus

    Full Text Available Donate Today! Become a Member Donate Now! One Time Monthly In Memory In Honor Become a Member En Español Type 1 Type 2 About Us Online Community Meal Planning Sign In Search: Search More Sites Search ≡ Are You At Risk? Diabetes Basics Living with Diabetes ...

  15. Action Type Deontic Logic

    DEFF Research Database (Denmark)

    Bentzen, Martin Mose

    2014-01-01

    are evaluated with respect to the benchmark cases. After that follows an informal introduction to the ideas behind the formal semantics, focussing on the distinction between action types and action tokens. Then the syntax and semantics of Action Type Deontic Logic is presented and it is shown to meet...

  16. Blood-type distribution

    Science.gov (United States)

    Kim, Beom Jun; Myeong Lee, Dong; Hun Lee, Sung; Gim, Wan-Suk

    2007-01-01

    We statistically verify the Hardy-Weinberg principle in genetics by investigating the independence of ABO-blood types of married couples. The allelic frequencies derived from the phenotypic frequencies in ethnic groups via the Hardy-Weinberg principle are used to define a genetic distance (called the blood distance in this work) between two groups. The blood distances are compared with the geographic distances, and then used to construct a network of ethnic groups. We also investigate the relationship between the ABO blood types and the human personalities, gauged by the Myers-Briggs-type indicator (MBTI) psychological test. The statistical χ2-test reveals the independence between the blood types and MBTI results with an exception of type B males. A psychological implication is discussed.

  17. Personality types of entrepreneurs.

    Science.gov (United States)

    Müller, Günter F; Gappisch, Cathrin

    2005-06-01

    85 German entrepreneurs were psychometrically assessed on 12 primary trait characteristics. The sample consisted of 49 men and 36 women whose mean age was 45.6 yr. (SD= 10.3). Occupational domains were production (40%) and services (60%). The mean duration of entrepreneurship within these domains was 13.1 yr. (SD=9.3). By factor analysis five personality types of entrepreneurs could be identified: Creative Acquisitor, Controlled Perseverator, Distant Achiever, Rational Manager, and Egocentric Agitator. These types correspond with types found in research by Miner and with the Myer-Briggs Indicator. In addition, correlations between general type potential and both job and life satisfaction of entrepreneurs were found. The results are discussed with regard to intercultural stability of personality types and implications for research and application.

  18. Types Of Christian Tourism

    Directory of Open Access Journals (Sweden)

    Cornelia Petroman

    2015-10-01

    Full Text Available Christian tourism is asub-type of tourism where pilgrims travel alone or in group as missionaries orpilgrims or to spend their free time to recollect; it attracts a large numberof travellers. Christian tourism can be practiced by religious young people,missionaries, participants to religious convents, amateurs of religiouscruises, religious camps, visitors of religious attractions, religiousadventurers. Christian tourism can be considered a sub-type of religioustourism because of the large number of people involved in this type of tourismworldwide. Christian tourism as a sub-category of religious tourism coversthree main sub-types: traditional pilgrimage practiced by most world religions,missionary travel to different areas in the world, and confessional voyage. Thestructure of hospitality industry is common to all types of tourism but, fortraditional pilgrimage, there must be special places for the pilgrims to sleep,eat and pray, because they belong, in most cases, to the medium-income touristcategory.

  19. Diabetes mellitus type 1

    OpenAIRE

    Tøraasen, Lisa Vangen; Al-Sultan, Zainab

    2014-01-01

    Hvert år blir rundt 600 nordmenn diagnostisert med sykdommen diabetes type 1, og Norge er et av landene i verden med størst andel av barnediabetes. I dag er det 15 000- 20 000 personer i Norge som har diabetes type 1, og antall barn som får diabetes har fordoblet seg de siste 30 årene (Diabetesforbundet, 2014). Problemstillingen vår gikk ut på hvordan sykepleiere kan veilede og undervise ungdom med nyoppdaget diabetes type på sykehus. Ut i fra litteraturstudiet har vi arbeidet oss frem for å ...

  20. Diabetes mellitus type 1

    OpenAIRE

    Tøraasen, Lisa Vangen; Al-Sultan, Zainab

    2014-01-01

    Bacheloroppgave i sykepleie, 2014 Hvert år blir rundt 600 nordmenn diagnostisert med sykdommen diabetes type 1, og Norge er et av landene i verden med størst andel av barnediabetes. I dag er det 15 000- 20 000 personer i Norge som har diabetes type 1, og antall barn som får diabetes har fordoblet seg de siste 30 årene (Diabetesforbundet, 2014). Problemstillingen vår gikk ut på hvordan sykepleiere kan veilede og undervise ungdom med nyoppdaget diabetes type på sykehus. Ut i fra litteraturst...

  1. Type 2 diabetes models

    DEFF Research Database (Denmark)

    Gram, Dorte Xenia

    2012-01-01

    This chapter deals with type 2 diabetes in vivo models and techniques suitable for testing new anti-diabetic compounds. In particular, the testing of TRP antagonist for beneficial effects against type 2 diabetes is considered. There are many choices of both in vitro techniques and in vivo models......, impaired glucose tolerance, impaired insulin secretion, and insulin resistance in vivo and should, thus, be sufficient to demonstrate preclinical proof of concept of a TRP antagonist in type 2 diabetes in rodents. The experiments are suggestions and could be replaced or supplemented by others....

  2. Griscelli syndrome type-3

    Directory of Open Access Journals (Sweden)

    Bela J Shah

    2016-01-01

    Full Text Available Griscelli syndrome (GS is a rare autosomal recessive multisystem disorder of pigmentary dilution of skin, silver gray hair, variable immunodeficiency, neurological impairment, and abnormal accumulation of melanosomes in melanocytes. GS type 3 is characterized by hypomelanosis with no immunological and neurological manifestation. Prognosis is very good in type 3 GS and usually require no active intervention, as opposed to type 1 and 2 where early diagnosis and treatment plays a crucial role in patient's survival. The characteristic phenotypic appearance, especially the pigment dilution of the patient's hair, is emphasized here.

  3. Synthesis and Characterization of Bis-benzyl and Bis-allyl Complexes of Titanium(III) and Vanadium(III); Catalytic Isomerization of Alkenes with CpV(η3-C3H5)2

    NARCIS (Netherlands)

    Nieman, J.; Pattiasina, J.W.; Teuben, J.H.

    1984-01-01

    Reactions of CpTiCl2 (Cp = η5-C5H5) with RMgX (X = Cl, Br) yield the complexes CpTiR2 (R = CH2Ph, η3-C3H5). The complex Cp*Ti(η3-C3H5)2 (Cp* = η5-C5Me5) was prepared analogously from Cp*TiCl2(THF). CpVCl2(PEt3)2 and Cp´VCl2(PEt3)2 (Cp´ = η5-C5H4Me) were used for the preparation of CpV(CH2Ph)2,

  4. Search for neutral Higgs bosons in the multi-$b$-jet topology in 5.2fb$^{-1}$ of $p\\bar{p}$ collisions at $\\sqrt{s} = 1.96$ TeV

    Energy Technology Data Exchange (ETDEWEB)

    Abazov, Victor Mukhamedovich; /Dubna, JINR; Abbott, Braden Keim; /Oklahoma U.; Acharya, Bannanje Sripath; /Tata Inst.; Adams, Mark Raymond; /Illinois U., Chicago; Adams, Todd; /Florida State U.; Alexeev, Guennadi D.; /Dubna, JINR; Alkhazov, Georgiy D.; /St. Petersburg, INP; Alton, Andrew K.; /Michigan U. /Augustana Coll., Sioux Falls; Alverson, George O.; /Northeastern U.; Alves, Gilvan Augusto; /Rio de Janeiro, CBPF; Ancu, Lucian Stefan; /Nijmegen U. /Fermilab

    2010-11-01

    Data recorded by the D0 experiment at the Fermilab Tevatron Collider are analyzed to search for neutral Higgs bosons produced in association with b quarks. The search is performed in the three-b-quark channel using multijet-triggered events corresponding to an integrated luminosity of 5.2 fb{sup -1}. In the absence of any significant excess above background, limits are set on the cross section multiplied by the branching ratio in the Higgs boson mass range 90 to 300 GeV, extending the excluded regions in the parameter space of the minimal supersymmetric standard model.

  5. Facts about Type 2

    Medline Plus

    Full Text Available ... and Learning About Prediabetes Type 2 Diabetes Risk Test Lower Your Risk Healthy Eating Overweight Smoking High ... You at Risk? Diagnosis Lower Your Risk Risk Test Alert Day Prediabetes My Health Advisor Tools to ...

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    Full Text Available ... Eye Complications Neuropathy Foot Complications DKA (Ketoacidosis) & Ketones Kidney Disease (Nephropathy) Gastroparesis Mental Health Step On Up ... high blood glucose levels may hurt your eyes, kidneys, nerves or heart. Some people with type 2 ...

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  8. Facts about Type 2

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    Full Text Available ... form of diabetes. In type 2 diabetes, your body does not use insulin properly. This is called insulin resistance. At first, the ... Loss Fitness In My Community Calendar of Events ...

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    Full Text Available ... Care Blood Glucose Testing Medication Doctors, Nurses & More Oral Health & Hygiene Women A1C Insulin Pregnancy 8 Tips ... normal. Type 2 is treated with lifestyle changes, oral medications (pills), and insulin. When glucose builds up ...

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    Full Text Available ... Index Low-Calorie Sweeteners Sugar and Desserts Fitness Exercise & Type 1 Diabetes Get Started Safely Get And ... Diabetes causes more deaths a year than breast cancer and AIDS combined. Your gift today will help ...

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    Full Text Available ... Diets Meal Planning for Vegetarian Diets Cook with Heart-Healthy Foods Holiday Meal Planning What Can I ... levels may hurt your eyes, kidneys, nerves or heart. Some people with type 2 can control their ...

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  20. Facts about Type 2

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  3. Facts about Type 2

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  4. Facts about Type 2

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    Full Text Available ... Index Low-Calorie Sweeteners Sugar and Desserts Fitness Exercise & Type 1 Diabetes Get Started Safely Get And ... State Priorities Federal Priorities Advocacy Accomplishments Legal Advocacy Health Disparities Hometown Advocacy Easy Advocacy Checklists for Association ...

  5. Facts about Type 2

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    Full Text Available ... Test Lower Your Risk Healthy Eating Overweight Smoking High Blood Pressure Physical Activity High Blood Glucose My Health Advisor Tools To Know Your Risk Alert Day Diabetes Basics Home Symptoms Diagnosis America's Diabetes Challenge Type ...

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  9. Recommended Types of Sunglasses

    Science.gov (United States)

    ... Eyes? Recommended Types of Sunglasses Leer en Español: Tipos Recomendados de Anteojos de Sol Dec. 12, 2015 ... is linked to cataracts and eye growths, including cancer. UVB radiation is considered more dangerous to the ...

  10. Facts about Type 2

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    Full Text Available ... Health Insurance Update The Health Insurance Marketplace Health Insurance From an Employer Options for the Uninsured Medicare Medicaid & CHIP For Parents & Kids Safe at School Everyday Life Children and Type 2 Diabetes Know Your Rights ...

  16. Facts about Type 2

    Medline Plus

    Full Text Available ... seconds someone new is diagnosed. Diabetes causes more deaths a year than breast cancer and AIDS combined. ... as well as the aged population. Patient Education Materials — Taking Care of Type 2 Diabetes This two- ...

  17. Types of Hearing Aids

    Science.gov (United States)

    ... Consumer Devices Consumer Products Hearing Aids Types of Hearing Aids Share Tweet Linkedin Pin it More sharing ... are some features for hearing aids? What are hearing aids? Hearing aids are sound-amplifying devices designed ...

  18. Facts about Type 2

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    Full Text Available ... to Give Close Are You at Risk? Home Prevention Diagnosing Diabetes and Learning About Prediabetes Type 2 ... Dinners! A year of delicious meals to help prevent and manage diabetes. Healthy Recipes: Build a Better ...

  19. Facts about Type 2

    Medline Plus

    Full Text Available ... Get And Stay Fit Types of Activity Weight Loss Assess Your Lifestyle Getting Started Food Choices In ... Recipes Planning Meals What Can I Eat Weight Loss Fitness In My Community Calendar of Events Local ...

  20. Facts about Type 2

    Medline Plus

    Full Text Available ... Doctors, Nurses & More Oral Health & Hygiene Women A1C Insulin Pregnancy 8 Tips for Caregivers Health Insurance Health ... type 2 diabetes, your body does not use insulin properly. This is called insulin resistance. At first, ...

  1. Facts about Type 2

    Medline Plus

    Full Text Available ... a Member Donate Now! One Time Monthly In Memory In Honor Become a Member En Español Type ... time Give monthly Give in honor Give in memory Donate Now Why Give? Nearly 30 million battle ...

  2. Making Type Inference Practical

    DEFF Research Database (Denmark)

    Schwartzbach, Michael Ignatieff; Oxhøj, Nicholas; Palsberg, Jens

    1992-01-01

    We present the implementation of a type inference algorithm for untyped object-oriented programs with inheritance, assignments, and late binding. The algorithm significantly improves our previous one, presented at OOPSLA'91, since it can handle collection classes, such as List, in a useful way. Abo......, the complexity has been dramatically improved, from exponential time to low polynomial time. The implementation uses the techniques of incremental graph construction and constraint template instantiation to avoid representing intermediate results, doing superfluous work, and recomputing type information....... Experiments indicate that the implementation type checks as much as 100 lines pr. second. This results in a mature product, on which a number of tools can be based, for example a safety tool, an image compression tool, a code optimization tool, and an annotation tool. This may make type inference for object...

  3. Facts about Type 2

    Medline Plus

    Full Text Available ... Up Treatment & Care Blood Glucose Testing Medication Doctors, Nurses & More Oral Health & Hygiene Women A1C Insulin Pregnancy ... and Care Blood Glucose Control Complications Medication Doctors, Nurses & More Enroll in the Living With Type 2 ...

  4. Facts about Type 2

    Medline Plus

    Full Text Available ... and Learning About Prediabetes Type 2 Diabetes Risk Test Lower Your Risk Healthy Eating Overweight Smoking High ... excused. 86 million Americans have prediabetes. Take the test. Know where you stand. More from diabetes.org ...

  5. Type 1 diabetes

    DEFF Research Database (Denmark)

    Green, Anders; Kyvik, Kirsten Ohm

    2001-01-01

    Prediction of Type 1 diabetes at individual level is relevant for any possible intervention before clinical disease develops. Currently available markers of Type 1 diabetes include genetic specificities and immune markers, in addition to a positive family history. This chapter reviews the measures...... and methods of importance in predicting Type 1 diabetes. Based on numerical examples it is demonstrated that available markers have a low level of performance, even when combined. Even so, combined marker information may allow for the identification of the large majority of the general population who...... is at very low disease risk. The impact at population level of predicting Type 1 diabetes varies between societies because the performance of markers depends on levels of disease risk and distribution of markers within a population. The incorporation of the influence of non-genetic etiological factors may...

  6. Description of vegetation types

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This document provides descriptions of five vegetation types found in Iowa- oak savannah, mature hardwoods, floodplain woods, scrub woods, and riparian woods. Oak...

  7. Facts about Type 2

    Medline Plus

    Full Text Available ... Type 2 About Us Online Community Meal Planning Sign In Search: Search More Sites Search ≡ Are You ... diabetes news, research and food & fitness tips. Email: Sign Up Thank you for signing up ' + ' '); $('.survey-form'). ...

  8. Tissue types (image)

    Science.gov (United States)

    ... are 4 basic types of tissue: connective tissue, epithelial tissue, muscle tissue, and nervous tissue. Connective tissue supports ... binds them together (bone, blood, and lymph tissues). Epithelial tissue provides a covering (skin, the linings of the ...

  9. Facts about Type 2

    Medline Plus

    Full Text Available ... of Diabetes Research & Practice Home We Are Research Leaders World's Largest Diabetes Meeting Recent Advances Type 1 ... year of delicious meals to help prevent and manage diabetes. Ways to Give: Dress Up Your Donations - ...

  10. Facts about Type 2

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    Full Text Available ... WIth Type 2 Diabetes Program In It Together We Can Help Center for Information Legal Assistance Success Stories ... Offer. Double your impact to save lives. Donate We Can Help - we-can-help.html Chat Online Chat ...

  11. Facts about Type 2

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    Full Text Available ... Facebook Twitter Pinterest Youtube Instagram Diabetes Stops Here Blog Online Community Site Menu Are You at Risk? ... in the Living WIth Type 2 Diabetes Program Food & Fitness Food Recipes Planning Meals What Can I ...

  12. Facts about Type 2

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    Full Text Available ... of Diabetes Research & Practice Home We Are Research Leaders World's Largest Diabetes Meeting Recent Advances Type 1 ... Call to Congress Research & Practice We Are Research Leaders We Support Your Doctor Student Resources Patient Access ...

  13. Additional Types of Neuropathy

    Science.gov (United States)

    ... Camp Fundraising Events Step Out Walk to Stop Diabetes Tour de Cure Father of the Year Stop Diabetes at School ... Forecast Stop Diabetes Step Out: Walk to Stop Diabetes Tour de Cure Living With Type 2 Diabetes Recipes for Healthy ...

  14. Facts about Type 2

    Science.gov (United States)

    ... Camp Fundraising Events Step Out Walk to Stop Diabetes Tour de Cure Father of the Year Stop Diabetes at School ... Forecast Stop Diabetes Step Out: Walk to Stop Diabetes Tour de Cure Living With Type 2 Diabetes Recipes for Healthy ...

  15. Facts about Type 2

    Medline Plus

    Full Text Available ... not use insulin properly. This is called insulin resistance. At first, the pancreas makes extra insulin to ... as well as the aged population. Patient Education Materials — Taking Care of Type 2 Diabetes This two- ...

  16. Facts about Type 2

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    Full Text Available ... www.diabetes.org > Diabetes Basics > Type 2 Share: Print Page Text Size: A A A Listen En ... in PDF format so you can download it, print it, and hand it out to patients. You ...

  17. Types of Funerals

    Science.gov (United States)

    ... Funeral Terms and Contact Information Related Items Every family is different, and not everyone wants the same type of funeral. Funeral practices are influenced by religious and cultural traditions, costs, and personal preferences. These factors help determine ...

  18. Facts about Type 2

    Medline Plus

    Full Text Available ... of Diabetes Diabetes Myths A Day in the Life of Diabetes Famous People Working to Stop Diabetes ... CHIP For Parents & Kids Safe at School Everyday Life Children and Type 2 Diabetes Know Your Rights ...

  19. Facts about Type 2

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    Full Text Available ... Basics Living with Diabetes Food & Fitness In My Community Advocacy Research & Practice Ways to Give Close Are You at Risk? Home Prevention Diagnosing Diabetes and Learning About Prediabetes Type 2 Diabetes Risk Test Lower ...

  20. Facts about Type 2

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    Full Text Available ... Diagnosed Treatment and Care Blood Glucose Control Complications Medication Doctors, Nurses & More Enroll in the Living With Type 2 Diabetes Program donate en -- Match – Donate Now - match-donate- ...

  1. Facts about Type 2

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    Full Text Available ... is Gestational Diabetes? How to Treat Gestational Diabetes Genetics of Diabetes Diabetes Myths A Day in the ... 1 Type 2 Gestational Myths Statistics Common Terms Genetics Living With Diabetes Recently Diagnosed Treatment & Care Complications ...

  2. Facts about Type 2

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    Full Text Available ... or heart. Some people with type 2 can control their blood glucose with healthy eating and being ... 2 Recently Diagnosed Treatment and Care Blood Glucose Control Complications Medication Doctors, Nurses & More Enroll in the ...

  3. Facts about Type 2

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    Full Text Available ... Medicare Medicaid & CHIP For Parents & Kids Safe at School Everyday Life Children and Type 2 Diabetes Know ... Cure Father of the Year Stop Diabetes at School Tour de Cure Women's Series Destination Races Do- ...

  4. Facts about Type 2

    Medline Plus

    Full Text Available ... make enough insulin to keep your blood glucose levels normal. Type 2 is treated with lifestyle changes, ... starved for energy. Over time, high blood glucose levels may hurt your eyes, kidneys, nerves or heart. ...

  5. Facts about Type 2

    Medline Plus

    Full Text Available ... to Give Close Are You at Risk? Home Prevention Diagnosing Diabetes and Learning About Prediabetes Type 2 ... Dinners! A year of delicious meals to help prevent and manage diabetes. Ask the Experts: Learn to ...

  6. Facts about Type 2

    Medline Plus

    Full Text Available ... Diabetes Research & Practice Home We Are Research Leaders World's Largest Diabetes Meeting Recent Advances Type 1 Research ... new is diagnosed. Diabetes causes more deaths a year than breast cancer and AIDS combined. Your gift ...

  7. Facts about Type 2

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    Full Text Available ... Type 2 Diabetes Know Your Rights Employment Discrimination Health Care Professionals Law Enforcement Driver's License For Lawyers Food & ... Terms Genetics Living With Diabetes Recently Diagnosed Treatment & Care Complications Health Insurance For Parents & Kids Know Your Rights We ...

  8. Facts about Type 2

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    Full Text Available ... and Learning About Prediabetes Type 2 Diabetes Risk Test Lower Your Risk Healthy Eating Overweight Smoking High Blood Pressure Physical Activity High Blood Glucose My Health ...

  9. Type 1 diabetes

    OpenAIRE

    Atkinson, Mark A; Eisenbarth, George S; Michels, Aaron W

    2013-01-01

    Over the past decade, knowledge of the pathogenesis and natural history of type 1 diabetes has grown substantially, particularly with regard to disease prediction and heterogeneity, pancreatic pathology, and epidemiology. Technological improvements in insulin pumps and continuous glucose monitors help patients with type 1 diabetes manage the challenge of lifelong insulin administration. Agents that show promise for averting debilitating disease-associated complications have also been identifi...

  10. Type E botulism.

    Science.gov (United States)

    Horowitz, B Zane

    2010-11-01

    There are seven known serotypes of botulism, designated A through G; almost all human cases of botulism are caused by types A, B, and E. Botulism type E is the predominant serotype causing disease associated with native Arctic foods. In the circumpolar regions of the world, the coastal soils are rich in botulism type E, and consumption of fish and marine animals in these areas are the sources of clusters of botulism. Unlike spores of type A and B, botulism type E can withstand freezing down to 3.5°C. Alaskan native fermentation of fish heads, fish eggs, and beaver tail allow proper anaerobic conditions for botulinum toxin to be elaborated from Clostridium botulinum. The consumption of whale meat, "muktuk" has also been associated with outbreaks of botulism in Alaska and the Canadian Arctic. Elsewhere in the Arctic regions, type E botulism has been associated with Norwegian "rakfisk" prepared by a process similar to fermented Alaskan foods. Outbreaks in Egypt with the salted gray mullet "faseikh", in Israel and New York linked to salted uneviscerated whitefish "kapchunka", in Iran from eating "ashbal" an uncooked salmon, and in Japan with "izushi" a traditional fermented fish preserved in rice have occurred. Importation of vacuum-packed whitefish from Alaska and Canada has also been associated with sporadic cases of botulism type E in Europe. In March 2010, the Center for Disease Control and Prevention released the heptavalent antitoxin (H-BAT) for use in the USA, under an Investigational New Drug program, as the preferred treatment for food-borne botulism, including type E, which had not been covered by the bivalent antitoxin, the prior approved antitoxin product in the USA.

  11. Type extension trees

    DEFF Research Database (Denmark)

    Jaeger, Manfred

    2006-01-01

    We introduce type extension trees as a formal representation language for complex combinatorial features of relational data. Based on a very simple syntax this language provides a unified framework for expressing features as diverse as embedded subgraphs on the one hand, and marginal counts of at...... of attribute values on the other. We show by various examples how many existing relational data mining techniques can be expressed as the problem of constructing a type extension tree and a discriminant function....

  12. Neurofibromatosis type 2

    OpenAIRE

    Evans, D; Sainio, M; Baser, M

    2000-01-01

    Neurofibromatosis type 2 is an often devastating autosomal dominant disorder which, until relatively recently, was confused with its more common namesake neurofibromatosis type 1. Subjects who inherit a mutated allele of the NF2 gene inevitably develop schwannomas, affecting particularly the superior vestibular branch of the 8th cranial nerve, usually bilaterally. Meningiomas and other benign central nervous system tumours such as ependymomas are other common features. Much of the morbidity f...

  13. 2-Methylpyridinium/pyridinium 5-(2,4-dinitrophenyl)-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-olates as potent anticonvulsant agents—synthesis and crystal structure

    Energy Technology Data Exchange (ETDEWEB)

    Mangaiyarkarasi, G.; Kalaivani, D., E-mail: kalaivbalaj@yahoo.co.in [Affiliated to Bharathidasan University, Post Graduate and Research Department of Chemistry, Seethalakshmi Ramaswami College, Tiruchirappalli-620 002 (India)

    2013-12-15

    The molecular salt, 2-methylpyridinium 5-(2,4-dinitrophenyl)-2,6-dioxo-1,2,3,6-tetrahydropy-rimidin-4-olate) (I), is prepared from the ethanolic solution of 1-chloro-2,4-dinitrobenzene, pyrimidine-2,4,6-(1H,3H,5H)-trione (barbituric acid) and 2-methylpyridine at room temperature, and the molecular salt, pyridinium 5-(2,4-dinitrophenyl)-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-olate (II), is prepared from the same reactants, by dissolving them in hot DMSO and ethanol mixture at 70°C. The structures of I and II are characterized by visible, IR, {sup 1}H-NMR, {sup 13}C-NMR and elemental analysis and confirmed by single crystal X-ray analysis. Both the salts crystallize in triclinic crystal system with sp. gr. P-bar1. They possess noticeable anticonvulsant activity even at low concentration (25 mg/kg). Acute toxicity studies of these complexes indicate that LD{sub 50} values are greater than 1500 mg/kg and the tested animals do not show any behavioural changes.

  14. Type 4 cardiorenal syndrome.

    Science.gov (United States)

    Pinheiro da Silva, Ana Luísa; Vaz da Silva, Manuel Joaquim

    2016-11-01

    The Acute Dialysis Quality Initiative consensus conference proposed a classification of cardiorenal syndrome (CRS), aiming for a better delineation of each subtype. Although the exact pathophysiology of type 4 CRS is not completely understood, the mechanisms involved are probably multifactorial. There is growing evidence that oxidative stress is a major connector in the development and progression of type 4 CRS. Giving its complexity, poor prognosis and increasing incidence, type 4 CRS is becoming a significant public health problem. Patients with chronic kidney disease are particularly predisposed to cardiac dysfunction, due to the high prevalence of traditional cardiovascular risk factors in this population, but the contribution of risk factors specific to chronic kidney disease should also be taken into account. Much remains to be elucidated about type 4 CRS: despite progress over the last decade, there are still significant questions regarding its pathophysiology and there is as yet no specific therapy. A better understanding of the mechanisms involved may provide potential targets for intervention. The present review will provide a brief description of the definition, epidemiology, diagnosis, prognosis, biomarkers and management strategies of type 4 CRS, and the pathophysiological mechanisms and risk factors presumably involved in its development will be particularly highlighted. Copyright © 2016 Sociedade Portuguesa de Cardiologia. Publicado por Elsevier España, S.L.U. All rights reserved.

  15. Congenital fiber type disproportion.

    Science.gov (United States)

    Kissiedu, Juliana; Prayson, Richard A

    2016-04-01

    Type I muscle fiber atrophy in childhood can be encountered in a variety of neuromuscular disorders. Congenital fiber type disproportion (CFTD) is one such condition which presents as a nonprogressive muscle weakness. The diagnosis is often made after excluding other differential diagnostic considerations. We present a 2-year-9-month-old full term boy who presented at 2 months with an inability to turn his head to the right. Over the next couple of years, he showed signs of muscle weakness, broad based gait and a positive Gower's sign. He had normal levels of creatine kinase and normal electromyography. A biopsy of the vastus lateralis showed a marked variation in muscle fiber type. The adenosine triphosphate (ATP)-ase stains highlighted a marked type I muscle atrophy with rare scattered atrophic type II muscle fibers. No abnormalities were observed on the nicotinamide adenine dinucleotide (NADH), succinate dehydrogenase (SDH) or cytochrome oxidase stained sections. Ragged red fibers were not present on the trichrome stain. Abnormalities of glycogen or lipid deposition were not observed on the periodic acid-Schiff or Oil-Red-O stains. Immunostaining for muscular dystrophy associated proteins showed normal staining. Ultrastructural examination showed a normal arrangement of myofilaments, and a normal number and morphology for mitochondria. A diagnosis of CFTD was made after excluding other causes of type I atrophy including congenital myopathy. The lack of specific clinical and genetic disorder associated with CFTD suggests that it is a spectrum of a disease process and represents a diagnosis of exclusion. Copyright © 2015 Elsevier Ltd. All rights reserved.

  16. Brauer type embedding problems

    CERN Document Server

    Ledet, Arne

    2005-01-01

    This monograph is concerned with Galois theoretical embedding problems of so-called Brauer type with a focus on 2-groups and on finding explicit criteria for solvability and explicit constructions of the solutions. The advantage of considering Brauer type embedding problems is their comparatively simple condition for solvability in the form of an obstruction in the Brauer group of the ground field. This book presupposes knowledge of classical Galois theory and the attendant algebra. Before considering questions of reducing the embedding problems and reformulating the solvability criteria, the

  17. Type Inference for Session Types in the Pi-Calculus

    DEFF Research Database (Denmark)

    Graversen, Eva Fajstrup; Harbo, Jacob Buchreitz; Huttel, Hans

    2014-01-01

    In this paper we present a direct algorithm for session type inference for the π-calculus. Type inference for session types has previously been achieved by either imposing limitations and restriction on the π-calculus, or by reducing the type inference problem to that for linear types. Our approach...

  18. Crystal structure and biological evaluation of 4-methylmorpholin-4-ium 1,3-dimethyl-2,6-dioxo-5-(2,4,6-trinitrophenyl-1,2,3,6-tetrahydropyrimidin-4-olate

    Directory of Open Access Journals (Sweden)

    Jeganathan Gomathi

    2015-06-01

    Full Text Available The title molecular salt, C5H12NO+·C12H8N5O9− [common name: 4-methylmorpholin-4-ium 1,3-dimethyl-5-(2,4,6-trinitrophenylbarbiturate], possesses noticeable anticonvulsant and hypnotic activity. In the anion, the 1,3-dimethylbarbituric acid ring and the symmetrically substituted trinitrophenyl ring, linked via a C—C bond, are not coplanar but subtend an angle of 44.88 (7°. The six-membered ring of the 4-methylmorpholin-4-ium cation has a chair conformation. In the crystal, the cation and anion are linked via an N—H...O hydrogen bond. The cation–anion units are linked by a number of C—H...O hydrogen bonds, forming a three-dimensional network.

  19. Measurement of νμ-induced charged-current neutral pion production cross sections on mineral oil at Eν∈0.5-2.0GeV

    Science.gov (United States)

    Aguilar-Arevalo, A. A.; Anderson, C. E.; Bazarko, A. O.; Brice, S. J.; Brown, B. C.; Bugel, L.; Cao, J.; Coney, L.; Conrad, J. M.; Cox, D. C.; Curioni, A.; Dharmapalan, R.; Djurcic, Z.; Finley, D. A.; Fleming, B. T.; Ford, R.; Garcia, F. G.; Garvey, G. T.; Grange, J.; Green, C.; Green, J. A.; Hart, T. L.; Hawker, E.; Imlay, R.; Johnson, R. A.; Karagiorgi, G.; Kasper, P.; Katori, T.; Kobilarcik, T.; Kourbanis, I.; Koutsoliotas, S.; Laird, E. M.; Linden, S. K.; Link, J. M.; Liu, Y.; Liu, Y.; Louis, W. C.; Mahn, K. B. M.; Marsh, W.; Mauger, C.; McGary, V. T.; McGregor, G.; Metcalf, W.; Meyers, P. D.; Mills, F.; Mills, G. B.; Monroe, J.; Moore, C. D.; Mousseau, J.; Nelson, R. H.; Nienaber, P.; Nowak, J. A.; Osmanov, B.; Ouedraogo, S.; Patterson, R. B.; Pavlovic, Z.; Perevalov, D.; Polly, C. C.; Prebys, E.; Raaf, J. L.; Ray, H.; Roe, B. P.; Russell, A. D.; Sandberg, V.; Schirato, R.; Schmitz, D.; Shaevitz, M. H.; Shoemaker, F. C.; Smith, D.; Soderberg, M.; Sorel, M.; Spentzouris, P.; Spitz, J.; Stancu, I.; Stefanski, R. J.; Sung, M.; Tanaka, H. A.; Tayloe, R.; Tzanov, M.; van de Water, R. G.; Wascko, M. O.; White, D. H.; Wilking, M. J.; Yang, H. J.; Zeller, G. P.; Zimmerman, E. D.

    2011-03-01

    Using a custom 3-Čerenkov ring fitter, we report cross sections for νμ-induced charged-current single π0 production on mineral oil (CH2) from a sample of 5810 candidate events with 57% signal purity over an energy range of 0.5-2.0 GeV. This includes measurements of the absolute total cross section as a function of neutrino energy, and flux-averaged differential cross sections measured in terms of Q2, μ- kinematics, and π0 kinematics. The sample yields a flux-averaged total cross section of (9.2±0.3stat±1.5syst)×10-39cm2/CH2 at mean neutrino energy of 0.965 GeV.

  20. Probabilidades de transición para niveles 2S1/2, 2P1/2,3/2 y 2D3/2,5/2 del átomo de talio

    OpenAIRE

    Alonso Medina, Aurelia

    1996-01-01

    Se han calculado las probabilidades de transición radiativas para 203 líneas que se originan en los niveles ns 2 Si /2, np 2 Pi /2 , 3 /2 y nd 2D3/2 , 5 /2 del átomo TII. Las partes radiales de las funciones de onda se han calculado utilizando un potencial efectivo que incluye los efectos de polarización del "core", efectos relativistas y el tamaño finito del núcleo, considerándose también el efecto de polarización del " core" en el elemento de la matriz de transición. Las vidas med...

  1. Drying temperature effects on electrical and optical properties of poly[2-methoxy-5-(2’-ethyl-hexyloxy)-1,4-phenylene vinylene] (MEH-PPV) thin film

    Energy Technology Data Exchange (ETDEWEB)

    Azhar, N. E. A., E-mail: najwaezira@yahoo.com; Affendi, I. H. H., E-mail: irmahidayanti.halim@gmail.com; Shafura, A. K., E-mail: shafura@ymail.com; Shariffudin, S. S., E-mail: sobihana@gmail.com [NANO-ElecTronic Centre, Faculty of Electrical Engineering, Universiti Teknologi MARA (UiTM), 40450 Shah Alam, Selangor (Malaysia); Alrokayan, Salman A. H., E-mail: dr.salman@alrokayan.com; Khan, Haseeb A., E-mail: khan-haseeb@yahoo.com [Research Chair of Targeting and Treatment of Cancer Using Nanoparticles Department of Biochemistry, College of Science, King Saud University (KSU), 245 Riyadh 11454 (Saudi Arabia); Rusop, M., E-mail: rusop@salam.uitm.edu.my [NANO-ElecTronic Centre, Faculty of Electrical Engineering, Universiti Teknologi MARA (UiTM), 40450 Shah Alam, Selangor (Malaysia); NANO-SciTech Centre, Institute of Science, Universiti Teknologi MARA (UiTM), Shah Alam, Selangor (Malaysia)

    2016-07-06

    Temperature effects on electrical and optical properties of a representative semiconducting polymer, poly[2-methoxy-5-(2’-ethyl-hexyloxy)-1,4-phenylene vinylene] (MEH-PPV), has recently attracted much attention. The MEH-PPV thin films were deposited at different drying temperature (anneal temperature) using spin-coating technique. The spin coating technique was used to produce uniform film onto large area. The MEH-PPV was dissolved in toluene solution to exhibits different optical and electrical properties. The absorption coefficient and bandgap was measured using UV-Visible-NIR (UV-VIS-NIR). The bandgap of MEH-PPV was effect by the thickness of thin films. For electrical properties, two-point probe was used to characterize the current-voltage measurement. The current-voltage measurement shows that the MEH-PPV thin films become more conductive at high temperature. This study will provide better performance and suitable for optoelectronic device especially OLEDs applications.

  2. Atomic frequency reference at 1033 nm for ytterbium (Yb)-doped fiber lasers and applications exploiting a rubidium (Rb) 5S_1/2 to 4D_5/2 one-colour two-photon transition

    Science.gov (United States)

    Roy, Ritayan; Condylis, Paul C.; Johnathan, Yik Jinen; Hessmo, Björn

    2017-04-01

    We demonstrate a two-photon transition of rubidium (Rb) atoms from the ground state (5$S_{1/2}$) to the excited state (4$D_{5/2}$), using a home-built ytterbium (Yb)-doped fiber amplifier at 1033 nm. This is the first demonstration of an atomic frequency reference at 1033 nm as well as of a one-colour two-photon transition for the above energy levels. A simple optical setup is presented for the two-photon transition fluorescence spectroscopy, which is useful for frequency stabilization for a broad class of lasers. This spectroscopy has potential applications in the fiber laser industry as a frequency reference, particularly for the Yb-doped fiber lasers. This two-photon transition also has applications in atomic physics as a background- free high- resolution atom detection and for quantum communication, which is outlined in this article.

  3. Synthesis and Evaluation of in Vitro Biological Activity of 4-Substituted Arylpiperazine Derivatives of 1,7,8,9-Tetrachloro-10,10-dimethoxy-4-azatricyclo[5.2.1.02,6]dec-8-ene-3,5-dione

    Directory of Open Access Journals (Sweden)

    David Collu

    2009-12-01

    Full Text Available A series of twenty arylpiperazine derivatives of 1,7,8,9-tetrachloro-10,10-dimethoxy-4-azatricyclo[5.2.1.02,6]dec-8-ene-3,5-dione have been prepared. These derivatives were tested in vitro with the aim of identifying novel lead compounds active against emergent and re-emergent human and cattle infectious diseases (AIDS, hepatitis B and C, tuberculosis, bovine viral diarrhea. In particular, these compounds were evaluated in vitro against representatives of different virus classes, such as a HIV-1 (Retrovirus, a HBV (Hepadnavirus and the single-stranded RNA+ viruses Yellow fever virus (YFV and Bovine viral diarrhea virus (BVDV, both belonging to the Flaviridae. Compounds 2c, 2g and 3d showed a modest activity against CVB-2. The molecular structures of the starting imide 1 and one of propyl-piperazine derivatives, 3b, have been determined by an X-ray crystallography study.

  4. Facts about Type 2

    Medline Plus

    Full Text Available ... Are You At Risk? Diabetes Basics Living with Diabetes Food & Fitness In My Community Advocacy Research & Practice Ways to ... Help Enroll in the Living WIth Type 2 Diabetes Program Food & Fitness Food Recipes Planning Meals What Can I Eat ...

  5. Facts about Type 2

    Medline Plus

    Full Text Available ... type 2 diabetes. Shopdiabetes.org: Your Stress-Free System for Family Dinners! - 2017-03-book-oclock-scramble.html Shopdiabetes.org Your Stress-Free System for Family Dinners! A year of delicious meals ...

  6. Plaque Type Eryrhema Nodosum

    Directory of Open Access Journals (Sweden)

    Radha Mittal

    1987-01-01

    Full Text Available Three young females developed plaque type erythema nodosum. The underlying causes in them were tuberculosis chest, recurrent furunculosis and malaria respectively. All the three cases were under treatment at the time of development of erythema nodosum plaques and the onset was acute.

  7. Tension-type headache

    DEFF Research Database (Denmark)

    Bendtsen, Lars; Jensen, Rigmor

    2009-01-01

    The substantial societal and individual burdens associated with tension-type headache (TTH) constitute a previously overlooked major public health issue. TTH is prevalent, affecting up to 78% of the general population, and 3% suffer from chronic TTH. Pericranial myofascial nociception probably...

  8. Facts about Type 2

    Medline Plus

    Full Text Available ... 1 Type 2 About Us Online Community Meal Planning Sign In Search: Search More Sites Search ≡ Are ... Fitness Home Food MyFoodAdvisor Recipes Association Cookbook Recipes Planning Meals Diabetes Meal Plans Create Your Plate Gluten ...

  9. [DISEASES AND ITS TYPES].

    Science.gov (United States)

    Carmona, Manuel Domínguez

    2014-01-01

    With this conference, I intend to define what is the disease and its types explaining the criteria for classification according to different points of view, as the etiologic, teleological, social impact, spatial and temporal distribution, production mechanisms, risk factors, which affects organs, etc. As there are diseases that do not exist dedicate a final chapter of this dissertation to develop them.

  10. Facts about Type 2

    Medline Plus

    Full Text Available ... Diabetes causes more deaths a year than breast cancer and AIDS combined. Your gift today will help us get closer to ... normal. Type 2 is treated with lifestyle changes, oral medications (pills), and insulin. When glucose builds up ...

  11. Facts about Type 2

    Medline Plus

    Full Text Available ... Asian Americans/Pacific Islanders, as well as the aged population. Patient Education Materials — Taking Care of Type ... Diabetes Association Alert Day® Advocacy Take Action Advocacy Priorities News & Events The Cost of Diabetes Advocate Toolkit ...

  12. Facts about Type 2

    Medline Plus

    Full Text Available ... Last Edited: October 27, 2015 Articles from Diabetes Forecast® magazine: lp-type-2, . In this section Diabetes ... Use and Privacy Policy « American Diabetes Association Diabetes Forecast Stop Diabetes Step Out: Walk to Stop Diabetes ...

  13. Facts about Type 2

    Medline Plus

    Full Text Available ... Risk Healthy Eating Overweight Smoking High Blood Pressure Physical Activity High Blood Glucose My Health Advisor Tools To ... Plate Gluten Free Diets Meal Planning for Vegetarian Diets Cook with Heart-Healthy ... Desserts Fitness Exercise & Type 1 Diabetes Get Started Safely Get And ...

  14. Facts about Type 2

    Medline Plus

    Full Text Available ... you may need to later on. Some groups have a higher risk for developing type 2 diabetes ... Online Chat Closed engagement en -- So…Do You Have Prediabetes? - 2017-01-ad-council.html So…Do ...

  15. Facts about Type 2

    Medline Plus

    Full Text Available ... Right away, your cells may be starved for energy. Over time, high blood glucose levels may hurt your eyes, kidneys, nerves or heart. Some people with type 2 can control their blood glucose with healthy eating and being active. But, your doctor may need ...

  16. Type 2 Diabetes

    Science.gov (United States)

    ... growth and obesity — increases the risk of diabetes. Complications Type 2 diabetes can be easy to ignore, especially in the ... can help prevent these complications. Although long-term complications of diabetes develop gradually, they can eventually be disabling or ...

  17. Facts about Type 2

    Medline Plus

    Full Text Available ... Diabetes causes more deaths a year than breast cancer and AIDS combined. Your gift today will help us get closer to curing ... Type 2 is treated with lifestyle changes, oral medications (pills), and insulin. When glucose builds up ...

  18. Type 1 Diabetes Facts

    Science.gov (United States)

    ... Type 1 Diabetes (T1D) Back Close What Is Diabetes? Causes of T1D The Complexity of Diagnosing T1D T1D ... about Insulin and T1D Learn More What Is Diabetes? Causes of T1D The Complexity of Diagnosing T1D T1D ...

  19. [C4 type photosynthesis].

    Science.gov (United States)

    Drozak, Anna; Wasilewska, Wioleta; Buczyńska, Alicja; Romanowska, Elzbieta

    2012-01-01

    C4 photosynthesis includes several anatomical and biochemical modifications that allow plants to concentrate CO2 at the site of Rubisco. The photorespiratory pathway is repressed in C4 plants, since the rates of photosynthesis and biomass production are increased. This is an adaptation to high light intensities, high temperatures and dryness. C4 plants contain two distinct types of photosynthetic cells, mesophyll and bundle sheath. The processes of assimilation and reduction of CO2 are separated spatiality and catayzed by two different enzymes. Only the bundle sheath chloroplasts perform the reactions of the Calvin-Benson cycle with the help of the Rubisco enzyme present exclusively in this cell type. The primary CO2 fixation occurs in mesophyll cells through the action of the phosphoenolpyruvate carboxylase. The light-dependent reactions of the photosynthesis occur exclusively in the latter cell type. These differences in photochemistry lead to distinct redox profiles in both types of cells. C4 plants are divided into three biochemical subtypes on the basis of differences in the mechanisms of decarboxylation of the C4 acids. C4 plants will provide the main source of food for humans and animals in the nearest decade.

  20. Gesture Types for Functions

    Science.gov (United States)

    Herbert, Sandra

    2012-01-01

    This paper reports on the different gesture types employed by twenty-three Year 10 students as they endeavoured to explain their understanding of rate of change associated with the functions resulting from two different computer simulations. These gestures also have application to revealing students' understanding of functions. However,…

  1. Types of Heart Block

    Science.gov (United States)

    ... defects. Acquired heart block is more common than congenital heart block. Damage to the heart muscle or its electrical system causes acquired heart block. Diseases, surgery, or medicines can cause this damage. The three types of heart block are first degree, second degree, ...

  2. Facts about Type 2

    Medline Plus

    Full Text Available ... Care Blood Glucose Testing Medication Doctors, Nurses & More Oral Health & Hygiene Women A1C Insulin Pregnancy 8 Tips for ... But, your doctor may need to also prescribe oral medications or insulin to help you meet your target blood glucose levels. Type 2 usually gets worse ... Health Advisor Tools to Know Your Risk Diabetes Basics ...

  3. TypeScript essentials

    CERN Document Server

    Nance, Christopher

    2014-01-01

    The book introduces the TypeScript language and its features to anyone looking to develop rich web applications. Whether you are new to web development or are an experienced engineer with strong JavaScript skills, this book will get you writing code quickly. A basic understanding of JavaScript and its language features are necessary for this book.

  4. Types of Timberland Ownership

    Science.gov (United States)

    William C. Siegel

    1999-01-01

    The form of ownership in which you hold your woodland is important from a tax standpoint. Further, if your forest property is structured as a business, the type of business organization chosen also has significant tax implications. Additionally, non-tax factors bear on choosing an ownership and/or business format. These include forest management goals, size of the...

  5. Types of Blood Donations

    Science.gov (United States)

    ... a Successful Donation Donation FAQs Types of Donations Power Red Platelets Plasma Autologous and Directed First Time Donors The Fear of Needles LGBTQ+ Donors Blood Donor Community SleevesUp Games Facebook Avatars and Badges Banners eCards Leaders Save Lives High school and college students can ...

  6. Facts about Type 2

    Medline Plus

    Full Text Available ... first, you may need to later on. Some groups have a higher risk for developing type 2 ... function (data) { $('#survey-errors').remove(); $('.survey-form .form-group .survey-alert-wrap').remove(); if (data.submitSurveyResponse.success == ' ...

  7. Type 1 narcolepsy

    DEFF Research Database (Denmark)

    Degn, Matilda; Kornum, Birgitte Rahbek

    2015-01-01

    Type 1 narcolepsy is a sleep disorder characterized by excessive daytime sleepiness with unintentional sleep attacks and cataplexy. The disorder is caused by a loss of hypocretinergic neurons in the brain. The specific loss of these neurons in narcolepsy is thought to result from an autoimmune...

  8. Facts about Type 2

    Medline Plus

    Full Text Available ... Camp Fundraising Events Step Out Walk to Stop Diabetes Tour de Cure Father of the Year Stop Diabetes at School ... Forecast Stop Diabetes Step Out: Walk to Stop Diabetes Tour de Cure Living With Type 2 Diabetes Recipes for Healthy ...

  9. Facts about Type 2

    Medline Plus

    Full Text Available ... Diabetes causes more deaths a year than breast cancer and AIDS combined. Your gift today will help us get closer ... time, high blood glucose levels may hurt your eyes, kidneys, nerves or heart. Some people with type 2 ...

  10. Compositional data types

    DEFF Research Database (Denmark)

    Bahr, Patrick; Hvitved, Tom

    2011-01-01

    -cut fusion style deforestation which yields considerable speedups. We demonstrate our framework in the setting of compiler construction, and moreover, we compare compositional data types with generic programming techniques and show that both are comparable in run-time performance and expressivity while our...

  11. Facts about Type 2

    Medline Plus

    Full Text Available ... donate en -- Match – Donate Now - match-donate-now.html Match – Donate Now Make your year-end donation ... Donate Today We Can Help - we-can-help.html Chat Online Chat Closed engagement en -- Free Type ...

  12. Teaching to the Type

    Science.gov (United States)

    Tucker, Maggie

    2008-01-01

    Before she became an art teacher, the author relates that she worked at a graphic design agency and there she learned to fully appreciate typefaces and how they influence messages. In the years that she taught middle school art, the author has incorporated some basics of type design into her graphics unit, along with calligraphy, printmaking, and…

  13. Facts about Type 2

    Medline Plus

    Full Text Available ... My Community Advocacy Research & Practice Ways to Give Close Are You at Risk? Home Prevention Diagnosing Diabetes and Learning About Prediabetes Type 2 Diabetes Risk Test Lower Your Risk Healthy Eating Overweight Smoking High Blood Pressure Physical Activity High Blood Glucose My Health Advisor ...

  14. Facts about Type 2

    Medline Plus

    Full Text Available ... conversation about type 2 diabetes. Shopdiabetes.org: Your Stress-Free System for Family Dinners! - 2017-03-book-oclock-scramble.html Shopdiabetes.org Your Stress-Free System for Family Dinners! A year of ...

  15. Glutaric Acidemia Type 1

    OpenAIRE

    Hedlund, Gary L.; Longo, Nicola; Pasquali, Marzia

    2006-01-01

    Glutaric acidemias comprise different disorders resulting in an increased urinary excretion of glutaric acid. Glutaric acidemia type 1 (GA-1) is an autosomal recessive disorder of lysine, hydroxylysine, and tryptophan metabolism caused by deficiency of glutaryl-CoA dehydrogenase. It results in the accumulation of 3-hydroxyglutaric and glutaric acid. Affected patients can present with brain atrophy and macrocephaly and with acute dystonia secondary to striatal degeneration in most cases trigge...

  16. Conditional Belief Types

    Science.gov (United States)

    2016-04-19

    1994) and Heifetz and Mongin (2001). The axioms in such languages are analogous to the axioms on set-theoretic operators. However, the modal logic...Fagin and Halpern, 1994) that allows the description of expectations, by introducing a strong inference rule ( Heifetz and Mongin, 2001), or by...502. Heifetz , A. and P. Mongin (2001), “Probability logic for type spaces,” Games and Economic Behavior, 35, 31–53. Keynes, J. M. (1921), A Treatise

  17. Type Families with Class, Type Classes with Family

    DEFF Research Database (Denmark)

    Serrano, Alejandro; Hage, Jurriaan; Bahr, Patrick

    2015-01-01

    Type classes and type families are key ingredients in Haskell programming. Type classes were introduced to deal with ad-hoc polymorphism, although with the introduction of functional dependencies, their use expanded to type-level programming. Type families also allow encoding type-level functions......, now as rewrite rules. This paper looks at the interplay of type classes and type families, and how to deal with shortcomings in both of them. Furthermore, we show how to use families to simulate classes at the type level. However, type families alone are not enough for simulating a central feature...... of type classes: elaboration, that is, generating code from the derivation of a rewriting. We look at ways to solve this problem in current Haskell, and propose an extension to allow elaboration during the rewriting phase....

  18. Relative rates of biosynthesis of collagen type I, type V and type VI in calf cornea.

    OpenAIRE

    Kern, P.; Menasche, M.; Robert, L

    1991-01-01

    The biosynthesis of type I, type V and type VI collagens was studied by incubation of calf corneas in vitro with [3H]proline as a marker. Pepsin-solubilized collagen types were isolated by salt fractionation and quantified by SDS/PAGE. Expressed as proportions of the total hydroxyproline solubilized, corneal stroma comprised 75% type I, 8% type V and 17% type VI collagen. The rates of [3H]proline incorporation, linear up to 24 h for each collagen type, were highest for type VI collagen and lo...

  19. The human anti-HIV antibodies 2F5, 2G12, and PG9 differ in their susceptibility to proteolytic degradation: down-regulation of endogenous serine and cysteine proteinase activities could improve antibody production in plant-based expression platforms.

    Science.gov (United States)

    Niemer, Melanie; Mehofer, Ulrich; Torres Acosta, Juan Antonio; Verdianz, Maria; Henkel, Theresa; Loos, Andreas; Strasser, Richard; Maresch, Daniel; Rademacher, Thomas; Steinkellner, Herta; Mach, Lukas

    2014-04-01

    The tobacco-related species Nicotiana benthamiana has recently emerged as a promising host for the manufacturing of protein therapeutics. However, the production of recombinant proteins in N. benthamiana is frequently hampered by undesired proteolysis. Here, we show that the expression of the human anti-HIV antibodies 2F5, 2G12, and PG9 in N. benthamiana leaves leads to the accumulation of discrete heavy chain-derived degradation products of 30-40 kDa. Incubation of purified 2F5 with N. benthamiana intercellular fluid resulted in rapid conversion into the 40-kDa fragment, whereas 2G12 proved largely resistant to degradation. Such a differential susceptibility to proteolytic attack was also observed when these two antibodies were exposed to various types of proteinases in vitro. While serine and cysteine proteinases are both capable of generating the 40-kDa 2F5 fragment, the 30-kDa polypeptide is most readily obtained by treatment with the latter class of enzymes. The principal cleavage sites reside within the antigen-binding domain, the VH -CH 1 linker segment and the hinge region of the antibodies. Collectively, these results indicate that down-regulation of endogenous serine and cysteine proteinase activities could be used to improve the performance of plant-based expression platforms destined for the production of biopharmaceuticals. Copyright © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  20. Composing and decomposing data types

    DEFF Research Database (Denmark)

    Bahr, Patrick

    2014-01-01

    data types and to define extensible functions on data types in an ad hoc manner. The implementation makes essential use of closed type families in Haskell. The use of closed type families instead of type classes comes with a set of trade-offs, which we review in detail. Finally, we show that our......Wouter Swierstra's data types à la carte is a technique to modularise data type definitions in Haskell. We give an alternative implementation of data types à la carte that offers more flexibility in composing and decomposing data types. To achieve this, we refine the subtyping constraint, which...... is at the centre of data types à la carte. On the one hand this refinement is more general, allowing subtypings that intuitively should hold but were not derivable beforehand. This aspect of our implementation removes previous restrictions on how data types can be combined. On the other hand our refinement is more...

  1. Type-2 Fuzzy Curve Model

    Science.gov (United States)

    Adesah, R. S.; Zakaria, R.; Wahab, A. F.; Talibe, A.

    2017-09-01

    The paper discusses about the formulation of type-2 fuzzy curve model. The generalization is carried out due to the existence of complex uncertainty which cannot be represented with classical type-1 fuzzy set. Hence, type-2 fuzzy set is proposed to define this type of complex uncertainty. Based on the complex uncertainty of data, fuzzy set theory type-2 with fuzzy number type-2 concept is used to represent the data with complex uncertainty. This process re-defines the data as type-2 fuzzy data which is also the result obtained by generalizing type-1 fuzzy data. Therefore, B-spline function is chosen to show the development of type-2 B-spline curve model via generalization. It is then followed by a number of processes, i.e. fuzzification, reduction and defuzzification are defined to model type-2 fuzzy B-spline curve to obtain a crisp type-2 fuzzy curve.

  2. Diabetes Mellitus Type 1

    OpenAIRE

    Trydal, Kari

    2015-01-01

    Hvert år får rundt 300 barn og 600 voksne diabetes mellitus type 1, og til sammen har rundt 28 000 personer denne sykdommen i Norge i dag. Det er en kronisk metabolsk sykdom, med en absolutt insulinmangel. Gjennom litteratur og forskning er det vist, at for å forebygge senkomplikasjoner, trenger pasienten informasjon, undervisning og praktisk veiledning når det gjelder medisinering, kosthold og fysisk aktivitet, og motivering til å mestre sykdommen. I praksis vil sykepleier spille en aktiv ro...

  3. Representing Session Types

    DEFF Research Database (Denmark)

    Bock, Peter Brottveit; Murawska, Agata; Bruni, Alessandro

    2016-01-01

    In this paper we propose a logical foundation of processes and their focused normal forms. We use a linear meta-language based on substructural operational semantics to describe focused forms of processes, and compare them to standard π-calculus processes with their respective operational semanti....... The overall goal of this research is to understand how to reason about processes, multiparty communication and global types, and how to mechanize properties such as deadlock freeness and liveness. We are also interested in establishing the limitations of this approach....

  4. Laryngeal cleft type 1

    Directory of Open Access Journals (Sweden)

    Danilo de Assis Pereira

    2015-06-01

    Full Text Available The clinical itinerary and the institution of conservative therapy in a case of laryngeal cleft type 1 refers to a child born by cesarean section, Apgar 9 and 10, a history of placental nd abruption in the 2 month of pregnancy, with respiratory nd distress on the 2 day of life and difficulty in breast feeding mothers. Presented evidence of aspiration pneumonia. The videodeglutogram showed aspiration of large amounts of material contrasted during swallowing. In bronchoscopy was visualized formation of threadlike small slit making the diagnosis of laryngeal cleft. We then decided, by institution of conservative treatment with enteral nutrition training and thickened with swallowing.

  5. Type 1 autoimmune pancreatitis

    Directory of Open Access Journals (Sweden)

    Zen Yoh

    2011-12-01

    Full Text Available Abstract Before the concept of autoimmune pancreatitis (AIP was established, this form of pancreatitis had been recognized as lymphoplasmacytic sclerosing pancreatitis or non-alcoholic duct destructive chronic pancreatitis based on unique histological features. With the discovery in 2001 that serum IgG4 concentrations are specifically elevated in AIP patients, this emerging entity has been more widely accepted. Classical cases of AIP are now called type 1 as another distinct subtype (type 2 AIP has been identified. Type 1 AIP, which accounts for 2% of chronic pancreatitis cases, predominantly affects adult males. Patients usually present with obstructive jaundice due to enlargement of the pancreatic head or thickening of the lower bile duct wall. Pancreatic cancer is the leading differential diagnosis for which serological, imaging, and histological examinations need to be considered. Serologically, an elevated level of IgG4 is the most sensitive and specific finding. Imaging features include irregular narrowing of the pancreatic duct, diffuse or focal enlargement of the pancreas, a peri-pancreatic capsule-like rim, and enhancement at the late phase of contrast-enhanced images. Biopsy or surgical specimens show diffuse lymphoplasmacytic infiltration containing many IgG4+ plasma cells, storiform fibrosis, and obliterative phlebitis. A dramatic response to steroid therapy is another characteristic, and serological or radiological effects are normally identified within the first 2 or 3 weeks. Type 1 AIP is estimated as a pancreatic manifestation of systemic IgG4-related disease based on the fact that synchronous or metachronous lesions can develop in multiple organs (e.g. bile duct, salivary/lacrimal glands, retroperitoneum, artery, lung, and kidney and those lesions are histologically identical irrespective of the organ of origin. Several potential autoantigens have been identified so far. A Th2-dominant immune reaction and the activation of

  6. Marine Bromophenol Derivative 3,4-Dibromo-5-(2-bromo-3,4-dihydroxy-6-isopropoxymethyl benzylbenzene-1,2-diol Protects Hepatocytes from Lipid-Induced Cell Damage and Insulin Resistance via PTP1B Inhibition

    Directory of Open Access Journals (Sweden)

    Jiao Luo

    2015-07-01

    Full Text Available 3,4-Dibromo-5-(2-bromo-3,4-dihydroxy-6-isopropoxymethyl benzylbenzene-1,2-diol (HPN is a bromophenol derivative from the marine red alga Rhodomela confervoides. We have previously found that HPN exerted an anti-hyperglycemic property in db/db mouse model. In the present study, we found that HPN could protect HepG2 cells against palmitate (PA-induced cell death. Data also showed that HPN inhibited cell death mainly by blocking the cell apoptosis. Further studies demonstrated that HPN (especially at 1.0 μM significantly restored insulin-stimulated tyrosine phosphorylation of IR and IRS1/2, and inhibited the PTP1B expression level in HepG2 cells. Furthermore, the expression of Akt was activated by HPN, and glucose uptake was significantly increased in PA-treated HepG2 cells. Our results suggest that HPN could protect hepatocytes from lipid-induced cell damage and insulin resistance via PTP1B inhibition. Thus, HPN can be considered to have potential for the development of anti-diabetic agent that could protect both hepatic cell mass and function.

  7. Search for the standard model Higgs boson in the ZH->vvbb channel in 5.2 fb-1 of p-pbar collisions at sqrt(s)=1.96 TeV

    Energy Technology Data Exchange (ETDEWEB)

    Abazov, V.M.; /Dubna, JINR; Abbott, B.; /Oklahoma U.; Abolins, M.; /Michigan State U.; Acharya, B.S.; /Tata Inst.; Adams, M.; /Illinois U., Chicago; Adams, T.; /Florida State U.; Aguilo, E.; /Simon Fraser U. /York U., Canada; Alexeev, G.D.; /Dubna, JINR; Alkhazov, G.; /St. Petersburg, INP; Alton, A.; /Michigan State U.; Alverson, G.; /Northeastern U. /Rio de Janeiro, CBPF

    2009-12-01

    A search is performed for the standard model Higgs boson in 5.2 fb{sup -1} of p{bar p} collisions at {radical}s = 1.96 TeV, collected with the D0 detector at the Fermilab Tevatron Collider. The final state considered is a pair of b jets and large missing transverse energy, as expected from p{bar p} {yields} ZH {yields} {nu}{bar {nu}}b{bar b} production. The search is also sensitive to the WH {yields} {ell}{nu}b{bar b} channel when the charged lepton is not identified. For a Higgs boson mass of 115 GeV, a limit is set at the 95% C.L. on the cross section multiplied by branching fraction for (p{bar p} {yields} (Z/W)H) x (H {yields} b{bar b}) that is a factor of 3.7 larger than the standard model value, consistent with the factor of 4.6 expected.

  8. Controlling Morphology and Aggregation in Semiconducting Polymers: The Role of Solvents on Lasing Emission in Poly[2-methoxy-5-(2'-ethyl-hexyloxy)-1,4-phenylene-vinylene].

    Science.gov (United States)

    Liu, Minghuan; Liu, Yonggang; Peng, Zenghui; Yang, Chengliang; Mu, Quanquan; Cao, Zhaoliang; Ma, Ji; Xuan, Li

    2017-06-29

    Systematic experiments were performed to investigate solvent-dependent morphology and aggregation of the semiconducting polymer film poly[2-methoxy-5-(2'-ethyl-hexyloxy)-1,4-phenylene-vinylene] (MEH-PPV), which was span-cast from nonaromatic strong polarity solvents tetrahydrofuran (THF), trichloromethane (TCM) and aromatic weak polarity solvents chlorobenzene (CB), toluene, and p-xylene. The results indicated that the conformation of the spin-cast MEH-PPV films with weak aggregation such as THF and TCM demonstrated excellent lasing emission performances because of inhibiting the fluorescence quenching induced by bi-molecule process. The Atomic Force Microscope (AFM) images confirmed the distinct morphologies of the spin-cast MEH-PPV films. The amplified spontaneous emission (ASE) was investigated in a simple asymmetric slab planar waveguide structure by methods of variable stripe length (VSL) and shifting excitation stripe (SES). The amplified spontaneous emission (ASE) experiments confirmed the distinct polymer chain conformation. The conformation, which preserved from the spin-cast process, indicated the distinct interactions between solvents and MEH-PPV polymer chains. The pure film spectra were performed to confirm the effect of distinct conformation on the material energy level. This work provides insights into the morphology and aggregation effect of the spin-cast polymer films on the performances of lasers.

  9. Employing the plasmonic effect of the Ag-graphene composite for enhancing light harvesting and photoluminescence quenching efficiency of poly[2-methoxy-5-(2-ethylhexyloxy)-1,4-phenylene-vinylene].

    Science.gov (United States)

    Ran, Chenxin; Wang, Minqiang; Gao, Weiyin; Yang, Zhi; Deng, Jianping; Ding, Jijun; Song, Xiaohui

    2014-03-14

    In this work, we report that the Ag-graphene composite (AGC) can effectively enhance the light harvesting and photoluminescence (PL) quenching efficiency of poly[2-methoxy-5-(2-ethylhexyloxy)-1,4-phenylene-vinylene] (MEH-PPV). Loading the AGC on MEH-PPV leads to improved light absorption ability and PL quenching efficiency, which is due to the strong interaction between localized surface plasmon resonance (LSPR)-activated Ag nanoparticles and the MEH-PPV molecule. Control experiment reveals that the combination of graphene and Ag nanoparticles achieves superior light absorptivity and PL quenching ability compared with individual graphene and Ag NPs. The exponential shape of the Stern-Volmer plot implies that both Ag and graphene in the AGC can offer the quenching pathway for the PL quenching process. We also found that the AGC with a broader LSPR absorption range is competitive in enhancing the light absorption ability and PL quenching efficiency of the MEH-PPV-AGC composite, because it can expand LSPR-induced light harvesting and PL quenching response to a wider absorption range.

  10. Discovery of a Clinical Stage Multi Kinase Inhibitor Sodium (E)-2-{2-Methoxy-5-[(2′, 4′, 6′-trimethoxystyrylsulfonyl)methyl]phenylamino}acetate (ON 01910.Na): Synthesis, Structure Activity Relationship and Biological Activity

    Science.gov (United States)

    Reddy, M.V. Ramana; Venkatapuram, Padmavathi; Mallireddigari, Muralidhar R; Pallela, Venkat R; Cosenza, Stephen C; Robell, Kimberly A; Akula, Balaiah; Hoffman, Benjamin S; Reddy, E. Premkumar

    2011-01-01

    Cyclin D proteins are elevated in many cancer cells and targeted deletion of Cyclin D1 gene in the mammary tissues protects mice from breast cancer. Accordingly, there is an increasing awareness of this novel non-enzymatic target for cancer therapeutics. We have developed novel, non-alkylating styryl benzyl sulfones that induce cell death in wide variety of cancer cells without affecting the proliferation and survival of normal cells. The development of derivatized Styryl Benzyl Sulfones followed logically from a tumor cell cytotoxicity screen performed in our laboratory that did not have an a priori target profile. Modifications of some of the precursor molecules led to lead optimization with regard to tumor cell cytotoxicity. In this report we describe the synthesis and structure-activity relationships of novel, non-alkylating (E) styryl benzyl sulfones, and the development of the novel anti-cancer agent sodium (E)-2-{2-methoxy-5-[(2′,4′,6′-trimethoxystyrylsulfonyl)methyl]phenylamino}-acetate (ON 01910.Na), which is in Phase III trials for myelodysplastic syndromes (MDS) associated with aberrant expression of cyclin D proteins. PMID:21812421

  11. Moment Contribution Capacity of Tendon Prestressed Partial on Concrete Beam-column Joint Interior According to Provisions ACI 318-2008 Chapter 21.5.2.5(c Due to Cyclic Lateral Loads

    Directory of Open Access Journals (Sweden)

    Astawa Made Dharma

    2016-01-01

    Full Text Available This research designed a partial prestressed concrete beam-column with reinforced concrete interior joint, using square columns of 400/400 mm, reinforcement 6 D16 + 4D13, section beam 250/400 mm, tensile reinforcement 5 D13, compression reinforcement 3 D13 + 2 strand tendon D12,7 mm , and joint without plastic hinge, then tested in laboratory with lateral cyclic loads on peak column, static axial load 1120 kN on the centre column, to get the tendon capacity to assume positive and negative bending moments due to lateral load, according to provisions of ACI 318-2008 part 21.5.2.5 (c. Test results showed that the moment tendon contribution on beam section, in the tensile area, the positive and negative moment both on the left side or the right side column are all qualified ( 25 %. As for the negative moment, either left or right side column are all qualified (4.0. Although the contribution of positive moment capacity tendon in compression areas does not qualify, in overall, the reliability and ductility of the structure qualify.

  12. Spinocerebellar ataxia type 7.

    Science.gov (United States)

    Martin, Jean-Jacques

    2012-01-01

    Spinocerebellar ataxia type 7 (SCA7) is associated with progressive blindness, dominant transmission, and marked anticipation. SCA7 represents one of the polyglutamine expansion diseases with increase of CAG repeats. The gene maps to chromosome 3p12-p21.1. Normal values of CAG repeats range from 4 to 18. The SCA7 gene encodes a protein of largely unknown function, called ataxin-7. SCA7 is reported in many countries and ethnic groups. Its phenotypic expression depends on the number of expanded repeats. The infantile phenotype is very severe, with more than 100 repeats. The classic type has 50 to 55 repeats and is characterized by a combination of visual and ataxic disturbances lasting for 20-40 years.When the number of CAG repeats is between 36 and 43, the evolution is much slower, with few or no retinal abnormalities. A CAG repeat number from 18 to 35 is asymptomatic but predisposes to the development of the disorder when expanding to the pathological range through transmission. The diagnosis is made by molecular genetics. The neuropathology of the disorder includes atrophy of the spinocerebellar pathways, pyramidal tracts, and motor nuclei in the brainstem and spinal cord, a cone-rod sytrophy of the retina, and ataxin-7 immunoreactive neuronal intranuclear inclusions. The neuropathological features vary as a function of the number of CAG repeats. Present research deals mainly with the study of ataxin-7 in transfected neural cells and transgenic mouse models. 2012 Elsevier B.V. All rights reserved.

  13. Session Types at the Mirror

    Directory of Open Access Journals (Sweden)

    Luca Padovani

    2009-12-01

    Full Text Available We (redefine session types as projections of process behaviors with respect to the communication channels they use. In this setting, we give session types a semantics based on fair testing. The outcome is a unified theory of behavioral types that shares common aspects with conversation types and that encompass features of both dyadic and multi-party session types. The point of view we provide sheds light on the nature of session types and gives us a chance to reason about them in a framework where every notion, from well-typedness to the subtyping relation between session types, is semantically -rather than syntactically- grounded.

  14. Efficient Type Representation in TAL

    Science.gov (United States)

    Chen, Juan

    2009-01-01

    Certifying compilers generate proofs for low-level code that guarantee safety properties of the code. Type information is an essential part of safety proofs. But the size of type information remains a concern for certifying compilers in practice. This paper demonstrates type representation techniques in a large-scale compiler that achieves both concise type information and efficient type checking. In our 200,000-line certifying compiler, the size of type information is about 36% of the size of pure code and data for our benchmarks, the best result to the best of our knowledge. The type checking time is about 2% of the compilation time.

  15. Type 1 Tyrosinaemia

    LENUS (Irish Health Repository)

    Mannion, MA

    2016-06-01

    Tyrosinaemia type 1 (TYR1, OMIM# 276700) is a rare autosomal recessive disease that results from an enzyme defect that leads to a deficiency in fumarylacetoacetase (FAH)1. We present 3 cases of TYR1 in the Irish population over a 9 year period, the only cases known to have been diagnosed in Ireland since 1989. The common presenting symptom was hypoglycaemia and the diagnosis was made by the identification of the pathognomonic biomarker succinylacetone on urine organic acid analysis. We discuss the clinical presentation, biochemical and genetic results including one novel mutation. We also highlight the importance of early initiation of Nitisinone (NTBC), which reduces the complications of TYR1 and the incidence of liver transplantation in this population2.

  16. Type 2 diabetes mellitus

    DEFF Research Database (Denmark)

    DeFronzo, Ralph A; Ferrannini, Ele; Groop, Leif

    2015-01-01

    comorbidities), owing to hyperglycaemia and individual components of the insulin resistance (metabolic) syndrome. Environmental factors (for example, obesity, an unhealthy diet and physical inactivity) and genetic factors contribute to the multiple pathophysiological disturbances that are responsible...... for impaired glucose homeostasis in T2DM. Insulin resistance and impaired insulin secretion remain the core defects in T2DM, but at least six other pathophysiological abnormalities contribute to the dysregulation of glucose metabolism. The multiple pathogenetic disturbances present in T2DM dictate......Type 2 diabetes mellitus (T2DM) is an expanding global health problem, closely linked to the epidemic of obesity. Individuals with T2DM are at high risk for both microvascular complications (including retinopathy, nephropathy and neuropathy) and macrovascular complications (such as cardiovascular...

  17. Enteroendocrine cell types revisited

    DEFF Research Database (Denmark)

    Engelstoft, Maja S; Egerod, Kristoffer Lihme; Lund, Mari L

    2013-01-01

    The GI-tract is profoundly involved in the control of metabolism through peptide hormones secreted from enteroendocrine cells scattered throughout the gut mucosa. A large number of recently generated transgenic reporter mice have allowed for direct characterization of biochemical and cell...... biological properties of these previously highly elusive enteroendocrine cells. In particular the surprisingly broad co-expression of six functionally related hormones in the intestinal enteroendocrine cells indicates that it should be possible to control not only the hormone secretion but also the type...... and number of enteroendocrine cells. However, this will require a more deep understanding of the factors controlling differentiation, gene expression and specification of the enteroendocrine cells during their weekly renewal from progenitor cells in the crypts of the mucosa....

  18. Mechanoluminescent Contact Type Sensor

    Directory of Open Access Journals (Sweden)

    A. K. Yefremov

    2017-01-01

    Full Text Available Mechanoluminescent sensing elements convert mechanical stress into optical radiation. Advantages of such sensors are the ability to generate an optical signal, solid-state, simple structure, and resistance to electromagnetic interference. Mechanoluminescent sensor implementations can possess the concentrated and distributed sensitivity, thereby allowing us to detect the field of mechanical stresses distributed across the area and in volume. Most modern semiconductor photo-detectors can detect mechanoluminescent radiation, so there are no difficulties to provide its detection when designing the mechanoluminescent sensing devices. Mechanoluminescent substances have especial sensitivity to shock loads, and this effect can be used to create a fuse the structure of which includes a target contact type sensor with a photosensitive actuator. The paper briefly describes the theoretical basics of mechanoluminiscence: a light signal emerges from the interaction of crystalline phosphor luminescence centers with electrically charged dislocations, moving due to the deformation of the crystal. A mathematical model of the mechanoluminescent conversion is represented as a functional interaction between parameters of the mechanical shock excitation and the sensor light emission. Examples of computing the optical mechanoluminescent output signal depending on the duration and peak level of impulse load are given. It is shown that the luminous flux, generated by mechanoluminescent sensing element when there is an ammunition-target collision causes the current emerging in photo-detector (photodiode that is sufficient for a typical actuator of the fuse train to operate. The potential possibility to create a contact target type sensor based on the light-sensitive mechanoluminescent sensor was proved by the calculation and simulation results.

  19. Type 1 diabetes mellitus.

    Science.gov (United States)

    Katsarou, Anastasia; Gudbjörnsdottir, Soffia; Rawshani, Araz; Dabelea, Dana; Bonifacio, Ezio; Anderson, Barbara J; Jacobsen, Laura M; Schatz, Desmond A; Lernmark, Åke

    2017-03-30

    Type 1 diabetes mellitus (T1DM), also known as autoimmune diabetes, is a chronic disease characterized by insulin deficiency due to pancreatic β-cell loss and leads to hyperglycaemia. Although the age of symptomatic onset is usually during childhood or adolescence, symptoms can sometimes develop much later. Although the aetiology of T1DM is not completely understood, the pathogenesis of the disease is thought to involve T cell-mediated destruction of β-cells. Islet-targeting autoantibodies that target insulin, 65 kDa glutamic acid decarboxylase, insulinoma-associated protein 2 and zinc transporter 8 - all of which are proteins associated with secretory granules in β-cells - are biomarkers of T1DM-associated autoimmunity that are found months to years before symptom onset, and can be used to identify and study individuals who are at risk of developing T1DM. The type of autoantibody that appears first depends on the environmental trigger and on genetic factors. The pathogenesis of T1DM can be divided into three stages depending on the absence or presence of hyperglycaemia and hyperglycaemia-associated symptoms (such as polyuria and thirst). A cure is not available, and patients depend on lifelong insulin injections; novel approaches to insulin treatment, such as insulin pumps, continuous glucose monitoring and hybrid closed-loop systems, are in development. Although intensive glycaemic control has reduced the incidence of microvascular and macrovascular complications, the majority of patients with T1DM are still developing these complications. Major research efforts are needed to achieve early diagnosis, prevent β-cell loss and develop better treatment options to improve the quality of life and prognosis of those affected.

  20. Pregnancy in women with type 1 diabetes

    DEFF Research Database (Denmark)

    Colstrup, Miriam; Mathiesen, Elisabeth R; Damm, Peter

    2013-01-01

    Abstract Objective: In 1989 the St. Vincent declaration set a five-year target for approximating outcomes of pregnancies in women with diabetes to those of the background population. We investigated and quantified the risk of adverse pregnancy outcomes in pregnant women with type 1 diabetes (T1DM......) to evaluate if the goals of the 1989 St. Vincent Declaration have been obtained concerning foetal and neonatal complications. Methods: Twelve population-based studies published within the last 10 years with in total 14 099 women with T1DM and 4 035 373 women from the background population were identified....... The prevalence of four foetal and neonatal complications was compared. Results: In women with T1DM versus the background population, congenital malformations occurred in 5.0% (2.2-9.0) (weighted mean and range) versus 2.1% (1.5-2.9), relative risk (RR) = 2.4, perinatal mortality in 2.7% (2.0-6.6) versus 0.72% (0...

  1. ÿþM i c r o s o f t W o r d - a a m , 2 0 0 9 , v o l . 8 , N o . 1 , 5 2

    African Journals Online (AJOL)

    ÿþE m m a n u e l A m e h

    2008-08-29

    Aug 29, 2008 ... Abstract. Background: Type 2 diabetes (T2D) is a major cause of chronic kidney disease. Control of hypertension and the use of angiotensin converting enzyme inhibitors (ACEI) and/or angiotensin II receptor blockers especially in those with proteinuria have been shown to protect against chronic kidney ...

  2. Object-Oriented Type Systems

    DEFF Research Database (Denmark)

    Schwartzbach, Michael Ignatieff; Palsberg, Jens

    Object-Oriented Type Systems Jens Palsberg and Michael I. Schwartzbach Aarhus University, Denmark Type systems are required to ensure reliability and efficiency of software. For object-oriented languages, typing is an especially challenging problem because of inheritance, assignment, and late...... binding. Existing languages employ different type systems, and it can be difficult to compare, evaluate and improve them, since there is currently no uniform theory for such languages. This book provides such a theory. The authors review the type systems of Simula, Smalltalk, C++ and Eiffel and present...... a type system that generalizes and explains them. The theory is based on an idealized object-oriented language called BOPL (Basic Object Programming Language), containing common features of the above languages. A type system, type inference algorithm, and typings of inheritance and genericity...

  3. Object-Oriented Type Systems

    DEFF Research Database (Denmark)

    Schwartzbach, Michael Ignatieff; Palsberg, Jens

    a type system that generalizes and explains them. The theory is based on an idealized object-oriented language called BOPL (Basic Object Programming Language), containing common features of the above languages. A type system, type inference algorithm, and typings of inheritance and genericity...... binding. Existing languages employ different type systems, and it can be difficult to compare, evaluate and improve them, since there is currently no uniform theory for such languages. This book provides such a theory. The authors review the type systems of Simula, Smalltalk, C++ and Eiffel and present......Object-Oriented Type Systems Jens Palsberg and Michael I. Schwartzbach Aarhus University, Denmark Type systems are required to ensure reliability and efficiency of software. For object-oriented languages, typing is an especially challenging problem because of inheritance, assignment, and late...

  4. Session Types at the Mirror

    OpenAIRE

    Luca Padovani

    2009-01-01

    We (re)define session types as projections of process behaviors with respect to the communication channels they use. In this setting, we give session types a semantics based on fair testing. The outcome is a unified theory of behavioral types that shares common aspects with conversation types and that encompass features of both dyadic and multi-party session types. The point of view we provide sheds light on the nature of session types and gives us a chance to reason about them in a framework...

  5. [Type I cryoglobulinemia].

    Science.gov (United States)

    Höffkes, H G; Weber, F; Helmchen, U; Friedmann, B; Kribben, A; Uppenkamp, M; Philipp, T

    1995-07-14

    For 2 years a 52-year-old man had repeated bouts of purpura, arthralgia and fever. He was known to have abnormal monoclonal gammaglobulins, type IgG-lambda and vasculitis when he had another bout with acute renal failure and necrotizing ulcers in the legs. Several laboratory tests were abnormal: erythrocyte sedimentation rate (122 mm), haemoglobin level (9.1 g/dl), white cell count (32,000/microliters), platelet count (562,000/microliters), creatinine level (4.1 mg/dl) and liver enzyme activities. He also had proteinuria (4.5 g daily) and nephritic urinary sediments. The immunoglobulin was subtype IgG3, and a cryoglobulinaemia was also present. Total complement level (CH 50) was not measurable. Bone marrow aspirate revealed plasmocytoma infiltration, and renal biopsy demonstrated necrotizing arteritis, as well as granular subendothelial deposits of IgG and complement. After three plasma separations and initiation of the first treatment cycle with a four-day infusion of vincristine, doxorubicin and dexamethasone the creatinine concentration fell to within the normal range and the necroses healed slowly. No cryoglobulin activity has been demonstrable over the past 24 months.

  6. Tornado type wind turbines

    Science.gov (United States)

    Hsu, Cheng-Ting

    1984-01-01

    A tornado type wind turbine has a vertically disposed wind collecting tower with spaced apart inner and outer walls and a central bore. The upper end of the tower is open while the lower end of the structure is in communication with a wind intake chamber. An opening in the wind chamber is positioned over a turbine which is in driving communication with an electrical generator. An opening between the inner and outer walls at the lower end of the tower permits radially flowing air to enter the space between the inner and outer walls while a vertically disposed opening in the wind collecting tower permits tangentially flowing air to enter the central bore. A porous portion of the inner wall permits the radially flowing air to interact with the tangentially flowing air so as to create an intensified vortex flow which exits out of the top opening of the tower so as to create a low pressure core and thus draw air through the opening of the wind intake chamber so as to drive the turbine.

  7. Neurofibromatosis Type II

    Directory of Open Access Journals (Sweden)

    Akram Kasiri Ghahi

    2003-08-01

    Full Text Available Neurofibromatosis type 2 (NF2 is an inherited disease which is mainly characterized by the development of multiple schwannomas and meningiomas.  Incidence of the disease is about 1 in 60,000. Affected individuals inevitably develop schwannomas, typically affecting both auditory-vestibular nerve which lead in hearing loss and deafness. The majority of patients present with hearing loss, which is usually unilateral at onset and may be accompanied or preceded by tinnitus. Vestibular schwannomas may also cause dizziness or imbalance as a first symptom. Nausea, vomiting or true vertigo are rare symptoms, except in late-stage disease. NF II is caused by a defect in the gene that normally gives rise to a product called Merlin or Schwannomin, located on chromosome 22. Diagnosis is based on clinical and neuroimaging studies. Presymptomatic genetic testing is an integral part of the management of NF2 families. Prenatal diagnosis and pre-implantation genetic diagnosis is possible.

  8. Organ Type and Waiting Time

    Science.gov (United States)

    ... Your Child Adjust Camps Resources LIVING DONATION Facts Types Being a Living Donor About the Operation Financing Living Donation Home / Before The Transplant / About Organ Allocation / Organ Type & Waiting Time Organ Facts Heart ...

  9. Object-Oriented Type Systems

    DEFF Research Database (Denmark)

    Schwartzbach, Michael Ignatieff; Palsberg, Jens

    a type system that generalizes and explains them. The theory is based on an idealized object-oriented language called BOPL (Basic Object Programming Language), containing common features of the above languages. A type system, type inference algorithm, and typings of inheritance and genericity...... are provided for BOPL. Throughout, the results are related to the languages on which BOPL is based. This text offers advanced undergraduates and professional software developers a sound understanding of the key aspects of object-oriented type systems. All algorithms are implemented in a freely available......Object-Oriented Type Systems Jens Palsberg and Michael I. Schwartzbach Aarhus University, Denmark Type systems are required to ensure reliability and efficiency of software. For object-oriented languages, typing is an especially challenging problem because of inheritance, assignment, and late...

  10. Object-Oriented Type Systems

    DEFF Research Database (Denmark)

    Schwartzbach, Michael Ignatieff; Palsberg, Jens

    are provided for BOPL. Throughout, the results are related to the languages on which BOPL is based. This text offers advanced undergraduates and professional software developers a sound understanding of the key aspects of object-oriented type systems. All algorithms are implemented in a freely available......Object-Oriented Type Systems Jens Palsberg and Michael I. Schwartzbach Aarhus University, Denmark Type systems are required to ensure reliability and efficiency of software. For object-oriented languages, typing is an especially challenging problem because of inheritance, assignment, and late...... a type system that generalizes and explains them. The theory is based on an idealized object-oriented language called BOPL (Basic Object Programming Language), containing common features of the above languages. A type system, type inference algorithm, and typings of inheritance and genericity...

  11. Treatise on intuitionistic type theory

    CERN Document Server

    Granström, Johan Georg

    2011-01-01

    Intuitionistic type theory can be described, somewhat boldly, as a fulfillment of the dream of a universal language for science.  In particular, intuitionistic type theory is a foundation for mathematics and a programming language.

  12. Types of health care providers

    Science.gov (United States)

    ... Supplements Videos & Tools Español You Are Here: Home → Medical Encyclopedia → Types of health care providers URL of this page: //medlineplus.gov/ency/article/001933.htm Types of health care providers To ...

  13. Object-Oriented Type Systems

    DEFF Research Database (Denmark)

    Schwartzbach, Michael Ignatieff; Palsberg, Jens

    a type system that generalizes and explains them. The theory is based on an idealized object-oriented language called BOPL (Basic Object Programming Language), containing common features of the above languages. A type system, type inference algorithm, and typings of inheritance and genericity......Object-Oriented Type Systems Jens Palsberg and Michael I. Schwartzbach Aarhus University, Denmark Type systems are required to ensure reliability and efficiency of software. For object-oriented languages, typing is an especially challenging problem because of inheritance, assignment, and late...... are provided for BOPL. Throughout, the results are related to the languages on which BOPL is based. This text offers advanced undergraduates and professional software developers a sound understanding of the key aspects of object-oriented type systems. All algorithms are implemented in a freely available...

  14. Lectin typing of Campylobacter concisus

    DEFF Research Database (Denmark)

    Aabenhus, Rune Munck; Hynes, Sean O; Permin, Henrik

    2002-01-01

    A total of 44 clinical isolates and the type strain of the putative pathogen Campylobacter concisus were grouped based on their reactions with plant lectins. The optimized lectin typing system used C. concisus strains proteolytically pretreated and subsequently typed by using a panel of four...... lectins. The system grouped all 45 strains into 13 lectin reaction patterns, leaving no strain untypeable due to autoagglutination. Lectin types were both stable and reproducible....

  15. Type inference for COBOL systems

    NARCIS (Netherlands)

    A. van Deursen (Arie); L.M.F. Moonen (Leon)

    1998-01-01

    textabstractTypes are a good starting point for various software reengineering tasks. Unfortunately, programs requiring reengineering most desperately are written in languages without an adequate type system (such as COBOL). To solve this problem, we propose a method of automated type inference

  16. Case 22:Type II diabetes

    Science.gov (United States)

    Diabetes mellitus is characterized by elevated blood glucose levels. It is composed of two types depending on the pathogenesis. Type I diabetes is characterized by insulin deficiency and usually has its onset during childhood or teenage years. This is also called ketosis-prone diabetes. Type II diab...

  17. Exploring legacy systems using types

    NARCIS (Netherlands)

    A. van Deursen (Arie); L.M.F. Moonen (Leon)

    2000-01-01

    textabstractWe show how hypertext-based program understanding tools can achieve new levels of abstraction by using inferred type information for cases where the subject software system is written in a weakly typed language. We propose TypeExplorer, a tool for browsing COBOL legacy systems based on

  18. Synthesis of nanocrystalline Ba(MnTi) xFe 12-2 xO 19 powders by the sol-gel combustion method in citrate acid-metal nitrates system ( x=0, 0.5, 1.0, 1.5, 2.0)

    Science.gov (United States)

    Hong, Y. S.; Ho, C. M.; Hsu, H. Y.; Liu, C. T.

    2004-08-01

    Nano-size M-type hexaferrites Ba(MnTi) xFe 12-2 xO 19 powders are synthesized by using the sol-gel combustion method in nitrate citric acid systems. The spectra of FTIR, TGA, and DSC indicate that citric acid and nitrate ion were decomposed at the temperature between 170°C and 200°C. The largest exothermic peaks at 180-270°C, which are due to the combustion reaction between decomposed citric acid and nitrate, were observed in DSC curves. The X-ray diffraction patterns of Ba(MnTi) xFe 12-2 xO 19 annealed above 800°C manifest that all the species have hexagonal crystal structure with lattice constants of a=5.89-5.91 and c=23.11-23.28 Å. TEM observation of as-burnt powders of Ba(MnTi)Fe 12O 19 shows the powder particles have an average particle size of 50 nm. Magnetic hysteresis loop measurements of the series Ba(MnTi) xFe 12-2 xO 19, x=0.5-2.0, exhibit that the saturation magnetization ( Ms), the remanent magnetization ( Mr) and the coercitivity ( Hc) of compounds depend strongly on the chemical composition of materials. The maxium values of Ms (67.6 emu/g) and Mr (32.7 emu/g) of this series of compounds were found at x=1.0; however, the values of Hc and the areas of magnetic hysteresis loop of compounds decrease with increasing the value of x.

  19. Magnetoelastic Generator Type Transducer

    Directory of Open Access Journals (Sweden)

    A. K. Efremov

    2014-01-01

    Full Text Available Some issues relating to usage of magnetoelectric generator type transducers as the means of measuring intense dynamic loads and as a sensitive element of fuse contact target sensor (CTS are considered. Particular attention is paid to the magnetoanisotropic transducer (MAT, the principle of operation of which is based on the change of the magnetic field form caused by the applied mechanical load leading to the appearance of EMF in the output winding. The MAT, especially monolithic, has such advantages as high strength, reliability, endurance and design simplicity.The functional transducer schemes have been analyzed and for the first time it was shown that there is a possibility of using a version with only one output winding arranged in the magnetic conductor made of magnetically soft material such as structural steel. A mathematical model of transducer is proposed showing that the input signal formed by the external load is proportional to its derivative. With a sufficiently large time constant of the electric circuit and the implementation of a number of additional conditions the transducer may function as an integrator. By that it becomes possible to measure the parameters of dynamic processes having the duration of a few to tens of microseconds. Unlike the traditional transducers such as piezoelectric the output signal is not “masked” by the natural oscillations.The mechanism of the generator effect was considered leading to the “piezomagnetodynamic” model, which includes a number of phenomenological parameters. Some corresponding experimentally derived hysteresis curves are presented. Their vertical shift quantifies the generator effect and does not depend on the intensity of the magnetic field.As an example of practical application of the MAT some results of evaluation of the dynamic force characteristic of the heading part of a piezoelectric fuse are presented. The MAT was also used for the evaluation of back effects of the bullet

  20. Bioimpedance phase angle indicates catabolism in Type 2 diabetes.

    Science.gov (United States)

    Dittmar, M; Reber, H; Kahaly, G J

    2015-09-01

    Body cell mass is directly proportional to the bioimpedance phase-angle which is an indicator of the amount of electrical charge that cell membranes can hold and is an index of cellular health and function. To evaluate whether the bioimpedance phase angle is relevant for indicating catabolism in people with diabetes and whether it discriminates between people with diabetes receiving different types of therapy. A cross-sectional study was performed in 182 people with Type 2 diabetes and 107 age- and BMI-matched control subjects. The phase angle was measured at 5, 50 and 100 kHz using multifrequency bioimpedance analysis. The phase angles were compared among different diabetes therapy groups (untreated patients with diabetes, patients receiving oral antidiabetic drugs and patients receiving insulin therapy). The phase angle at 100 kHz strongly correlated with total body potassium (r = 0.70, P = 0.001), and was therefore a good indicator of body cell mass. The phase angle at 100 kHz discriminated more strongly between patients with Type 2 diabetes and control subjects than did the phase angle at 50 kHz. Compared with control subjects, patients with Type 2 diabetes had a smaller phase angle at 100 kHz (men: 5.2° vs. 4.5°, P measurement for assessing catabolic state in people with diabetes. © 2015 The Authors. Diabetic Medicine © 2015 Diabetes UK.

  1. Typing is writing: Linguistic properties modulate typing execution.

    Science.gov (United States)

    Pinet, Svetlana; Ziegler, Johannes C; Alario, F-Xavier

    2016-12-01

    Typing is becoming our preferred way of writing. Perhaps because of the relative recency of this change, very few studies have investigated typing from a psycholinguistic perspective. In addition, and despite obvious similarities between typing and handwriting, typing research has remained rather disconnected from handwriting research. The current study aimed at bridging this gap by evaluating how typing is affected by a number of psycholinguistic variables defined at the word, syllable, and letter levels. In a writing-to-dictation task, we assessed typing performance by measuring response accuracy, onset latencies - an index of response preparation and initiation - and interkeystroke intervals (IKIs) - an index of response execution processes. The lexical and sublexical factors revealed a composite pattern of effects. Lexical frequency improved response latencies and accuracy, while bigram frequency speeded up IKIs. Sound-spelling consistency improved latencies, but had an inhibitory effect on IKI. IKIs were also longer at syllable boundaries. Together, our findings can be fit within a framework for typed production that combines the previously developed theories of spelling and typing execution. At their interface, we highlight the need for an intermediate hierarchical stage, perhaps in the form of a graphemic buffer for typing.

  2. Object-Oriented Type Systems

    DEFF Research Database (Denmark)

    Schwartzbach, Michael Ignatieff; Palsberg, Jens

    are provided for BOPL. Throughout, the results are related to the languages on which BOPL is based. This text offers advanced undergraduates and professional software developers a sound understanding of the key aspects of object-oriented type systems. All algorithms are implemented in a freely available......Object-Oriented Type Systems Jens Palsberg and Michael I. Schwartzbach Aarhus University, Denmark Type systems are required to ensure reliability and efficiency of software. For object-oriented languages, typing is an especially challenging problem because of inheritance, assignment, and late...... binding. Existing languages employ different type systems, and it can be difficult to compare, evaluate and improve them, since there is currently no uniform theory for such languages. This book provides such a theory. The authors review the type systems of Simula, Smalltalk, C++ and Eiffel and present...

  3. Early onset type 2 diabetes

    DEFF Research Database (Denmark)

    Bo, A; Thomsen, R W; Nielsen, J S

    2017-01-01

    was more frequent and meeting physical activity recommendations less likely in persons with early-onset type 2 DM. CONCLUSIONS: We found a clear age-gradient, with increasing prevalence of clinical and behavioural risk factors the younger the onset age of type 2 DM. Younger persons with early-onset type 2......AIM: To examine the association between early onset of type 2 diabetes (DM) and clinical and behavioural risk factors for later diabetes complications. METHODS: We conducted a cross-sectional study of 5115 persons with incident type 2 DM enrolled during 2010-2015 in the Danish Centre for Strategic...... Research in Type 2 Diabetes-cohort. We compared risk factors at time of diagnosis among those diagnosed at ≤45 years (early-onset) with diagnosis age 46-55, 56-65 (average-onset = reference), 66-75, and >75 years (late-onset). Prevalence ratios (PRs) were computed using Poisson regression. RESULTS: Poor...

  4. Object-Oriented Type Systems

    DEFF Research Database (Denmark)

    Schwartzbach, Michael Ignatieff; Palsberg, Jens

    Object-Oriented Type Systems Jens Palsberg and Michael I. Schwartzbach Aarhus University, Denmark Type systems are required to ensure reliability and efficiency of software. For object-oriented languages, typing is an especially challenging problem because of inheritance, assignment, and late...... are provided for BOPL. Throughout, the results are related to the languages on which BOPL is based. This text offers advanced undergraduates and professional software developers a sound understanding of the key aspects of object-oriented type systems. All algorithms are implemented in a freely available...... binding. Existing languages employ different type systems, and it can be difficult to compare, evaluate and improve them, since there is currently no uniform theory for such languages. This book provides such a theory. The authors review the type systems of Simula, Smalltalk, C++ and Eiffel and present...

  5. Types for BioAmbients

    Directory of Open Access Journals (Sweden)

    Sara Capecchi

    2010-02-01

    Full Text Available The BioAmbients calculus is a process algebra suitable for representing compartmentalization, molecular localization and movements between compartments. In this paper we enrich this calculus with a static type system classifying each ambient with group types specifying the kind of compartments in which the ambient can stay. The type system ensures that, in a well-typed process, ambients cannot be nested in a way that violates the type hierarchy. Exploiting the information given by the group types, we also extend the operational semantics of BioAmbients with rules signalling errors that may derive from undesired ambients' moves (i.e. merging incompatible tissues. Thus, the signal of errors can help the modeller to detect and locate unwanted situations that may arise in a biological system, and give practical hints on how to avoid the undesired behaviour.

  6. Object-Oriented Type Inference

    DEFF Research Database (Denmark)

    Schwartzbach, Michael Ignatieff; Palsberg, Jens

    1991-01-01

    We present a new approach to inferring types in untyped object-oriented programs with inheritance, assignments, and late binding. It guarantees that all messages are understood, annotates the program with type information, allows polymorphic methods, and can be used as the basis of an op-timizing......-timizing compiler. Types are finite sets of classes and subtyping is set inclusion. Using a trace graph, our algorithm constructs a set of conditional type constraints and computes the least solution by least fixed-point derivation....

  7. Management of type IIb dyslipidemia.

    Science.gov (United States)

    Arai, Hidenori; Ishibashi, Shun; Bujo, Hideaki; Hayashi, Toshio; Yokoyama, Shinji; Oikawa, Shinichi; Kobayashi, Junji; Shirai, Kohji; Ota, Takao; Yamashita, Shizuya; Gotoda, Takanari; Harada-Shiba, Mariko; Sone, Hirohito; Eto, Masaaki; Suzuki, Hiroaki; Yamada, Nobuhiro

    2012-01-01

    Although the Japan Atherosclerosis Society guideline for the diagnosis and prevention of atherosclerosis cardiovascular diseases for the Japanese population provides targets for low-density lipoprotein (LDL) cholesterol, triglycerides, and high-density lipoprotein (HDL) cholesterol to prevent cardiovascular disease in patients with dyslipidemia, there is no guideline specifically targeting the treatment of type IIb dyslipidemia, which is one of the most common types of dyslipidemia, along with type IIa and type IV dyslipidemia. Type IIb dyslipidemia is important because it sometimes accompanies atherogenic lipid profiles, such as small, dense LDL, remnants, low HDL cholesterolemia. It is also associated with type 2 diabetes mellitus, metabolic syndrome, and chronic kidney disease (CKD), and most patients with familial combined hyperlipidemia (FCHL) show this phenotype; therefore, it is assumed that patients with type IIb dyslipidemia have a high risk for cardiovascular disease. Thus, the management of type IIb dyslipidemia is very important for the prevention of cardiovascular disease, so we have attempted to provide a guideline for the management of type IIb dyslipidemia.

  8. Type-safe pattern combinators

    DEFF Research Database (Denmark)

    Rhiger, Morten

    2009-01-01

    Macros still haven't made their way into typed higher-order programming languages such as Haskell and Standard ML. Therefore, to extend the expressiveness of Haskell or Standard ML, one must express new linguistic features in terms of functions that fit within the static type systems of these lan......Macros still haven't made their way into typed higher-order programming languages such as Haskell and Standard ML. Therefore, to extend the expressiveness of Haskell or Standard ML, one must express new linguistic features in terms of functions that fit within the static type systems...

  9. Florence Nightingale: her personality type.

    Science.gov (United States)

    Dossey, Barbara M

    2010-03-01

    This article casts new and refreshing light on Florence Nightingale's life and work by examining her personality type. Using the theory-based Myers-Briggs Type Indicator (MBTI), the author examines Nightingale's personality type and reveals that she was an introverted-intuitive-thinking-judging type. The merit of using the MBTI is that it allows us to more clearly understand three major areas of Nightingale's life that have been partially unacknowledged or misunderstood: her spiritual development as a practicing mystic, her management of her chronic illness to maintain her prodigious work output, and her chosen strategies to transform her visionary ideas into new health care and social realities.

  10. Equations of the mixed type

    CERN Document Server

    Bitsadze, A V

    1963-01-01

    Equations of the Mixed Type compiles a series of lectures on certain fundamental questions in the theory of equations of mixed type. This book investigates the series of problems concerning linear partial differential equations of the second order in two variables, and possessing the property that the type of the equation changes either on the boundary of or inside the considered domain. Topics covered include general remarks on linear partial differential equations of mixed type; study of the solutions of second order hyperbolic equations with initial conditions given along the lines of parab

  11. A Type System for Tom

    Directory of Open Access Journals (Sweden)

    Claude Kirchner

    2010-03-01

    Full Text Available Extending a given language with new dedicated features is a general and quite used approach to make the programming language more adapted to problems. Being closer to the application, this leads to less programming flaws and easier maintenance. But of course one would still like to perform program analysis on these kinds of extended languages, in particular type checking and inference. In this case one has to make the typing of the extended features compatible with the ones in the starting language. The Tom programming language is a typical example of such a situation as it consists of an extension of Java that adds pattern matching, more particularly associative pattern matching, and reduction strategies. This paper presents a type system with subtyping for Tom, that is compatible with Java's type system, and that performs both type checking and type inference. We propose an algorithm that checks if all patterns of a Tom program are well-typed. In addition, we propose an algorithm based on equality and subtyping constraints that infers types of variables occurring in a pattern. Both algorithms are exemplified and the proposed type system is showed to be sound and complete.

  12. Safety Analysis versus Type Inference with Partial Types

    DEFF Research Database (Denmark)

    Schwartzbach, Michael Ignatieff; Palsberg, Jens

    1992-01-01

    Safety analysis is an algorithm for determining if a term in an untyped lambda calculus with constants is safe, i.e., if it does not cause an error during evaluation. This ambition is also shared by algorithms for type inference. Safety analysis and type inference are based on rather different...... perspectives, however. Safety analysis is global in that it can only analyze a complete program. In contrast, type inference is local in that it can analyze pieces of a program in isolation. In this paper we prove that safety analysis is sound, relative to both a strict and a lazy operational semantics. We...... also prove that safety analysis accepts strictly more safe lambda terms than does type inference for simple types. The latter result demonstrates that global program analysis can be more precise than local ones....

  13. Types of subtalar joint facets.

    Science.gov (United States)

    Jung, Min-Ho; Choi, Byoung Young; Lee, Ji Yong; Han, Chang Sung; Lee, Jin Suk; Yang, Young Chul; Cho, Byung Pil

    2015-08-01

    Articular facets of the clinical subtalar joint (CSTJ) were analyzed using a total of 118 (right 57, left 61) dry, paired calcanei and tali from 68 Korean adult cadavers. The CSTJ facets were classified into the following three types depending on their continuity: type A, all three facets are separated; type B, the anterior and middle facets are partially connected; and type C, the anterior and middle facets are fused to form a single facet. The continuity between the anterior and middle facets was represented by the degree of separation (DS), which ranged between 2.00 (type A) and 1.00 (type C). Type A was most common (39.0 %) in calcanei and rarest (11.0 %) in tali. Matching of calcaneus-talus pairs yielded five combined types: A-A (11.0 %), A-B (28.0 %), B-B (18.6 %), B-C (13.6 %), and C-C (28.8 %). The mean DS was slightly greater in calcanei (1.53) than in tali (1.32), and decreased in the order of types A-A, A-B, B-B, B-C, and C-C. The intersecting angles between the anterior and middle facets, which are related to the mobility of the CSTJ, were inversely related to the DS. These findings indicate that the anterior and middle facets are fused more frequently in tali than in calcanei, and combinations of different CSTJ facet types (A-B, B-C) exist over 40 % of feet. Our results indicate that types with a smaller DS (such as B-C and C-C) are relatively mobile but less stable compared to those with a greater DS (such as A-A and A-B).

  14. The Temperament Types of Nursing Administrators in Hospital Nursing Service.

    Science.gov (United States)

    1984-05-01

    INTJ 3 1.56 ENFP 9 4.68 ENFJ 8 4.16 ENTP 5 2.60 ISFJ 7 3.64 ESTP 1 0.52 I SFP 1 0.52 a.INTP 0 0.00 ESFP 0 0.00 INFP 0 0.00 ISTP 0 0.00...Stated Administrative Position* Type 1 2 3 4 5 6 7 8 ESTJ 30 12 12 1 6 2 2 1 ISTJ 6 4 6 1 1 2 ENTJ 6 2 5 1 1 ESFJ 1 5 6 * INFJ I INTJ 1 1 ENFP 4 1 3 1...others develop. INTJ - Logical, critical, decisive innovator of ideas; . A serious, intent, highly independent, concerned with organization, determined and

  15. Adenocarcinoma of the urinary bladder, mesonephroid type: a rare case

    Directory of Open Access Journals (Sweden)

    Mahmoud Abbas

    2013-02-01

    Full Text Available Primary adenocarcinoma of the urinary bladder is a rare disease. It occurs in 0.5-2% of all bladder cancers and is discussed as the malignant counterpart of nephrogenic adenomas. We report a 46-year-old white female presented with gross hematuria for clinical examination. Histopathology revealed pT2, Pn1, L1, G2 adenocarcinoma of the bladder and carcinoma in situ according to the TNM classification. Computed tomography scan diagnostic was unremarkable. Patients with adenocarcinoma of the urinary bladder should be treated vigorously and without time delay. Only 7 cases of adenocarcinoma in the urinary bladder (mesonephroid have been described until now. We present a case of clear cell adenocarcinoma of the urinary bladder, mesonephroid type that early diagnosed and till now 3 months after the cystectomy without symptoms and without complications.

  16. Brauer algebras of type B

    NARCIS (Netherlands)

    Cohen, A.M.; Liu, S.

    2015-01-01

    For each n ≥ 1, we define an algebra having many properties that one might expect to hold for a Brauer algebra of type Bn. It is defined by means of a presentation by generators and relations. We show that this algebra is a subalgebra of the Brauer algebra of type Dn+1 and point out a cellular

  17. Diabetes Type 1 - Multiple Languages

    Science.gov (United States)

    ... Are Here: Home → Multiple Languages → All Health Topics → Diabetes Type 1 URL of this page: https://medlineplus.gov/languages/ ... V W XYZ List of All Topics All Diabetes Type 1 - Multiple Languages To use the sharing features on ...

  18. Linear contextual modal type theory

    DEFF Research Database (Denmark)

    Schack-Nielsen, Anders; Schürmann, Carsten

    Abstract. When one implements a logical framework based on linear type theory, for example the Celf system [?], one is immediately con- fronted with questions about their equational theory and how to deal with logic variables. In this paper, we propose linear contextual modal type theory that gives...

  19. Type 1 Diabetes and Sleep.

    Science.gov (United States)

    Farabi, Sarah S

    2016-02-01

    IN BRIEF In people with type 1 diabetes, sleep may be disrupted as a result of both behavioral and physiological aspects of diabetes and its management. This sleep disruption may negatively affect disease progression and development of complications. This review highlights key research findings regarding sleep in people with type 1 diabetes.

  20. Type 1 Diabetes and Sleep

    OpenAIRE

    Farabi, Sarah S.

    2016-01-01

    IN BRIEF In people with type 1 diabetes, sleep may be disrupted as a result of both behavioral and physiological aspects of diabetes and its management. This sleep disruption may negatively affect disease progression and development of complications. This review highlights key research findings regarding sleep in people with type 1 diabetes.

  1. Type-Directed Partial Evaluation

    DEFF Research Database (Denmark)

    Danvy, Olivier

    1998-01-01

    Type-directed partial evaluation uses a normalization function to achieve partial evaluation. These lecture notes review its background, foundations, practice, and applications. Of specific interest is the modular technique of offline and online type-directed partial evaluation in Standard ML of ...

  2. Type studies in Basidiomycetes. X

    NARCIS (Netherlands)

    Singer, R.

    1961-01-01

    For the first time a systematic study of the types and authentic specimens of agarics and boletes preserved in the Persoon Herbarium has been carried out. Some aspects of the possibilities of type analysis with regard to specimens over 130 year old are discussed. 137 species were analyzed. The

  3. Classification of Building Object Types

    DEFF Research Database (Denmark)

    Jørgensen, Kaj Asbjørn

    2011-01-01

    be managed by software applications and on the basis of building models. Classification systems with taxonomies of building object types have many application opportunities but can still be beneficial in data exchange between building construction partners. However, this will be performed by new methods...... and in strong connection with databases holding a wide range of object types....

  4. of Nigerian Type 2 diabetic

    African Journals Online (AJOL)

    degrees of generalized and central/abdominal fat, implying a greater risk of developing Type 2 DM in view of the relationship between body fat distribution and insulin resistance. Long term prospective studies are needed to define anthropometric indices predictive of the development of Type 2 DM, as well as its relation to ...

  5. Interpretations of Recursive Type Definitions

    DEFF Research Database (Denmark)

    Schwartzbach, Michael Ignatieff

    1992-01-01

    A system of hierarchical imperative types is extended to allow infinite values. The general structure of value assignments to types in the context of a hierarchy is considered, and it is shown that both a minimal and a maximal value assignment exist. We give two different characterizations of int...

  6. Type-Directed Partial Evaluation

    DEFF Research Database (Denmark)

    Danvy, Olivier

    1998-01-01

    Type-directed partial evaluation uses a normalization function to achieve partial evaluation. These lecture notes review its background, foundations, practice, and applications. Of specific interest is the modular technique of offline and online type-directed partial evaluation in Standard ML...

  7. Types of Managed Care Plans

    Science.gov (United States)

    ... Involved in Your Community Healthy Children > Family Life > Medical Home > Health Insurance > Types of Managed Care Plans Family Life Listen Español Text Size Email Print Share Types of Managed Care Plans Page Content Article Body ​Managed care plans have agreements with certain ...

  8. Intersection Types and Related Systems

    Directory of Open Access Journals (Sweden)

    Paweł Parys

    2017-02-01

    Full Text Available We present a new approach to the following meta-problem: given a quantitative property of trees, design a type system such that the desired property for the tree generated by an infinitary ground lambda-term corresponds to some property of a derivation of a type for this lambda-term, in this type system. Our approach is presented in the particular case of the language finiteness problem for nondeterministic higher-order recursion schemes (HORSes: given a nondeterministic HORS, decide whether the set of all finite trees generated by this HORS is finite. We give a type system such that the HORS can generate a tree of an arbitrarily large finite size if and only if in the type system we can obtain derivations that are arbitrarily large, in an appropriate sense; the latter condition can be easily decided.

  9. Textural properties of low-fat set-type yoghurt depending on mTG addition

    Directory of Open Access Journals (Sweden)

    Lívia Darnay

    2016-07-01

    Full Text Available Our aim was to determine how 0.5-2 U/g non-inactivated mTG affects the pH development and apparent viscosity during fermentation. Furthermore we wished to examine how the enzyme addition could change protein structure, gel strength and sensory characteristics by healthy low-fat set-type yoghurt product. Therefore commercial mTG enzyme preparation was added in different concentrations (0.5-2.0 U/g, in 0.5 U/g steps to 1.5 % bovine milk simultaneously with DVS starter culture. Our study revealed that enzyme dosage (0.5-2 U/g protein had no impact on pH development and apparent viscosity during fermentation when manufacturing low-fat (1.5 % set-type yoghurt. The addition of mTG contributed to 38 % more whey retention with incorporation of β-casein, and caused 44 % higher gel strength up to a level of 1 U/g protein.

  10. Definitions of histocompatibility typing terms.

    Science.gov (United States)

    Nunes, Eduardo; Heslop, Helen; Fernandez-Vina, Marcelo; Taves, Cynthia; Wagenknecht, Dawn R; Eisenbrey, A Bradley; Fischer, Gottfried; Poulton, Kay; Wacker, Kara; Hurley, Carolyn Katovich; Noreen, Harriet; Sacchi, Nicoletta

    2011-12-01

    Histocompatibility testing for stem cell and solid organ transplantation has become increasingly complex as newly discovered HLA alleles are described. HLA typing assignments reported by laboratories are used by physicians and donor registries for matching donors and recipients. To communicate effectively, a common language for histocompatibility terms should be established. In early 2010, representatives from Clinical, Registry, and Histocompatibility organizations joined together as the Harmonization of Histocompatibility Typing Terms Working Group to define a consensual language for laboratories, physicians, and registries to communicate histocompatibility typing information. The Working Group defined terms for HLA typing resolution, HLA matching, and a format for reporting HLA assignments. In addition, definitions of verification typing and extended typing were addressed. The original draft of the Definitions of Histocompatibility Typing Terms was disseminated to colleagues from each organization to gain feedback and create a collaborative document. Commentary gathered during this 90-day review period were discussed and implemented for preparation of this report. Histocompatibility testing continues to evolve; thus, the definitions agreed on today probably will require refinement and perhaps additional terminology in the future.

  11. P-type gallium nitride

    Science.gov (United States)

    Rubin, M.; Newman, N.; Fu, T.; Ross, J.; Chan, J.

    1997-08-12

    Several methods have been found to make p-type gallium nitride. P-type gallium nitride has long been sought for electronic devices. N-type gallium nitride is readily available. Discovery of p-type gallium nitride and the methods for making it will enable its use in ultraviolet and blue light-emitting diodes and lasers. pGaN will further enable blue photocathode elements to be made. Molecular beam epitaxy on substrates held at the proper temperatures, assisted by a nitrogen beam of the proper energy produced several types of p-type GaN with hole concentrations of about 5{times}10{sup 11} /cm{sup 3} and hole mobilities of about 500 cm{sup 2} /V-sec, measured at 250 K. P-type GaN can be formed of unintentionally-doped material or can be doped with magnesium by diffusion, ion implantation, or co-evaporation. When applicable, the nitrogen can be substituted with other group III elements such as Al. 9 figs.

  12. Wild type measles virus attenuation independent of type I IFN

    Directory of Open Access Journals (Sweden)

    Horvat Branka

    2008-02-01

    Full Text Available Abstract Background Measles virus attenuation has been historically performed by adaptation to cell culture. The current dogma is that attenuated virus strains induce more type I IFN and are more resistant to IFN-induced protection than wild type (wt. Results The adaptation of a measles virus isolate (G954-PBL by 13 passages in Vero cells induced a strong attenuation of this strain in vivo. The adapted virus (G954-V13 differs from its parental strain by only 5 amino acids (4 in P/V/C and 1 in the M gene. While a vaccine strain, Edmonston Zagreb, could replicate equally well in various primate cells, both G954 strains exhibited restriction to the specific cell type used initially for their propagation. Surprisingly, we observed that both G954 strains induced type I IFN, the wt strain inducing even more than the attenuated ones, particularly in human plasmacytoid Dendritic Cells. Type I IFN-induced protection from the infection of both G954 strains depended on the cell type analyzed, being less efficient in the cells used to grow the viral strain. Conclusion Thus, mutations in M and P/V/C proteins can critically affect MV pathogenicity, cellular tropism and lead to virus attenuation without interfering with the α/β IFN system.

  13. CT findings of muscular dystrophy; Limb girdle type (LG), myotonic type (MYD) and Duchenne type (DMD)

    Energy Technology Data Exchange (ETDEWEB)

    Saitoh, Hiroshi (Tokushima Univ. (Japan). School of Medicine)

    1991-07-01

    CT scans of muscles in patients with limb girdle type (LG), myotonic type (MYD) and Duchenne type (DMD) dystrophies were obtained at five different body levels: the neck, L3 vertebral body, pelvic girdle, thigh and lower leg. CT numbers, cross sectional areas (CSA) and %CSA of muscle or fat were evaluated in each muscle. The characteristic CT patterns for each type of muscular dystrophy were obtained. Compared with DMD, the gracilis and soleus were more severely damaged in LG and the biceps femoris remained relatively preserved among the hamstrings. In addition, the multifidus of the neck and sternocleidomastoid also were more severely damaged in MYD. This study suggests that CT scan will be useful in the differential diagnosis of these types of muscular dystrophy as well as in planning appropriate rehabilitation and detecting damaged muscles. (author).

  14. Modalities in homotopy type theory

    DEFF Research Database (Denmark)

    Rijke, Egbert; Shulman, Michael; Spitters, Bas

    2017-01-01

    Univalent homotopy type theory (HoTT) may be seen as a language for the category of ∞-groupoids. It is being developed as a new foundation for mathematics and as an internal language for (elementary) higher toposes. We develop the theory of factorization systems, reflective subuniverses......, and modalities in homotopy type theory, including their construction using a "localization" higher inductive type. This produces in particular the (n-connected, n-truncated) factorization system as well as internal presentations of subtoposes, through lex modalities. We also develop the semantics...

  15. Type Inference of Turbo Pascal

    DEFF Research Database (Denmark)

    Hougaard, Ole Ildsgaard; Schwartzbach, Michael I; Askari, Hosein

    1995-01-01

    Type inference is generally thought of as being an exclusive property of the functional programming paradigm. We argue that such a feature may be of significant benefit for also standard imperative languages. We present a working tool (available by WWW) providing these benefits for a full version...... of Turbo Pascal. It has the form of a preprocessor that analyzes programs in which the type annotations are only partial or even absent. The resulting program has full type annotations, will be accepted by the standard Turbo Pascal compiler, and has polymorphic use of procedures resolved by means of code...

  16. User Types in Online Applications

    Directory of Open Access Journals (Sweden)

    Ion IVAN

    2011-08-01

    Full Text Available Online applications are presented in the context of information society. Online applications characteristics are analyzed. Quality characteristics are presented in relation to online applications users. Types of users for AVIO application are presented. Use cases for AVIO application are identified. The limitations of AVIO application are defined. Types of users in online applications are identified. The threedimensional matrix of access to the online application resources is built. The user type-oriented database is structured. Access management of the fields related to the database tables is analyzed. The classification of online applications users is done.

  17. Nanomaterial cytotoxicity is composition, size, and cell type dependent.

    Science.gov (United States)

    Sohaebuddin, Syed K; Thevenot, Paul T; Baker, David; Eaton, John W; Tang, Liping

    2010-08-21

    Despite intensive research efforts, reports of cellular responses to nanomaterials are often inconsistent and even contradictory. Additionally, relationships between the responding cell type and nanomaterial properties are not well understood. Using three model cell lines representing different physiological compartments and nanomaterials of different compositions and sizes, we have systematically investigated the influence of nanomaterial properties on the degrees and pathways of cytotoxicity. In this study, we selected nanomaterials of different compositions (TiO2 and SiO2 nanoparticles, and multi-wall carbon nanotubes [MWCNTs]) with differing size (MWCNTs of different diameters 50 nm; but same length 0.5-2 microm) to analyze the effects of composition and size on toxicity to 3T3 fibroblasts, RAW 264.7 macrophages, and telomerase-immortalized (hT) bronchiolar epithelial cells. Following characterization of nanomaterial properties in PBS and serum containing solutions, cells were exposed to nanomaterials of differing compositions and sizes, with cytotoxicity monitored through reduction in mitochondrial activity. In addition to cytotoxicity, the cellular response to nanomaterials was characterized by quantifying generation of reactive oxygen species, lysosomal membrane destabilization and mitochondrial permeability. The effect of these responses on cellular fate - apoptosis or necrosis - was then analyzed. Nanomaterial toxicity was variable based on exposed cell type and dependent on nanomaterial composition and size. In addition, nanomaterial exposure led to cell type dependent intracellular responses resulting in unique breakdown of cellular functions for each nanomaterial: cell combination. Nanomaterials induce cell specific responses resulting in variable toxicity and subsequent cell fate based on the type of exposed cell. Our results indicate that the composition and size of nanomaterials as well as the target cell type are critical determinants of

  18. Florence Nightingale. Her personality type.

    Science.gov (United States)

    Dossey, B M

    1998-06-01

    The purpose of this article is to cast new and refreshing light on Florence Nightingale's life and work by examining her personality type. Using the theory-based Myers-Briggs Type Indicator (MBTI), the author examines Nightingale's personality type and reveals that she was an introverted-intuitive-thinking-judging (INTJ) type. The merit of using the MBTI is that it allows us to more clearly understand three major areas of Nightingale's life that have been partially unacknowledged or misunderstood: her spiritual development as a practicing mystic, her management of her chronic illness to maintain her prodigious work output, and her chosen strategies to transform her visionary ideas into new health care and social realities.

  19. Allegheny County Soil Type Areas

    Data.gov (United States)

    Allegheny County / City of Pittsburgh / Western PA Regional Data Center — This dataset contains soil type and soil classification, by area. Additional info at: http://mcdc.cas.psu.edu/datawiz.htm;...

  20. Forest Cover Types - Direct Download

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This map layer portrays general forest cover types for the United States. Data were derived from Advanced Very High Resolution Radiometer (AVHRR) composite images...

  1. UX Ori-Type Stars

    Science.gov (United States)

    Grinin, V.

    2017-06-01

    The brief review of the properties of the UX Ori type stars is presented. A special attention is given to the results of the Crimean program of the multi-year photometric and polarimetric observations of these stars.

  2. Distinguishing among electron injection types

    Science.gov (United States)

    Feynman, J.

    1987-01-01

    Three types of electron injections taking place in the near-earth region of the magnetotail have been distinguished previously using SCATHA particle and field data. Defining characteristics are given here for each type of event, and the positions of the magnetosphere where they are expected to occur are discussed. These three event types can be difficult to distinguish in data sets that are more limited than the SCATHA set that carried instruments detecting magnetic fields and charged particles over an energy range from eVs to MeVs. It is suggested that determining the magnetospheric regions at which each of these event types occurs will considerably clarify the phenomenological description of substorms available for theoretical analysis.

  3. Lepromatous leprosy of histoid type

    Directory of Open Access Journals (Sweden)

    Annigeri S

    2007-01-01

    Full Text Available Histoid leprosy is a variant of lepromatous leprosy, which develops as a result of resistance to dapsone monotherapy. Here we report two cases of lepromatous leprosy of histoid type, one with typical and another with atypical presentations.

  4. Type 2 Diabetes Risk Test

    Science.gov (United States)

    ... Camp Fundraising Events Step Out Walk to Stop Diabetes Tour de Cure Father of the Year Stop Diabetes at School ... Forecast Stop Diabetes Step Out: Walk to Stop Diabetes Tour de Cure Living With Type 2 Diabetes Recipes for Healthy ...

  5. Living with Type 1 Diabetes

    Science.gov (United States)

    ... Camp Fundraising Events Step Out Walk to Stop Diabetes Tour de Cure Father of the Year Stop Diabetes at School ... Forecast Stop Diabetes Step Out: Walk to Stop Diabetes Tour de Cure Living With Type 2 Diabetes Recipes for Healthy ...

  6. Pneumococcal Disease: Types of Infection

    Science.gov (United States)

    ... Many different bacteria, viruses, and even fungi can cause pneumonia. Pneumococcus is one of the most common causes of severe pneumonia. Besides pneumonia, pneumococcus can cause other types of ...

  7. [Sport and type 1 diabetes].

    Science.gov (United States)

    Büsser, C; Meyer, P; Philippe, J; Jornayvaz, F R

    2013-06-05

    Physical activity is recognised to be an efficient measure in improving glycemic control in the treatment of type 2 diabetes. This evidence is lacking in type I diabetes but type 1I diabetics benefit from the same advantages like the general population. For many type I diabetics, especially younger patients, sport represents an important modality in the treatment of their disease but also of their quality of life. However, this is often a challenge for the patient as well as for the physician regarding the metabolic consequences (hypo- but also hyperglycemia) which can appear in relation with physical activity. There are existing general recommendations concerning the intake of carbohydrates and the reduction of insulin doses but those have to be adapted individually for each patient and depend significantly on different sports and on the intensity of sport.

  8. Exercise and Type 2 Diabetes

    OpenAIRE

    Colberg, Sheri R.; Sigal, Ronald J.; Fernhall, Bo; Regensteiner, Judith G.; Blissmer, Bryan J.; Rubin, Richard R.; Chasan-Taber, Lisa; Albright, Ann L.; Braun, Barry

    2010-01-01

    Although physical activity (PA) is a key element in the prevention and management of type 2 diabetes, many with this chronic disease do not become or remain regularly active. High-quality studies establishing the importance of exercise and fitness in diabetes were lacking until recently, but it is now well established that participation in regular PA improves blood glucose control and can prevent or delay type 2 diabetes, along with positively affecting lipids, blood pressure, cardiovascular ...

  9. Recent advances in autoimmune pancreatitis: type 1 and type 2.

    Science.gov (United States)

    Kamisawa, Terumi; Chari, Suresh T; Lerch, Markus M; Kim, Myung-Hwan; Gress, Thomas M; Shimosegawa, Tooru

    2013-09-01

    Autoimmune pancreatitis (AIP) is a form of chronic pancreatitis characterised clinically by frequent presentation with obstructive jaundice, histologically by a lymphoplasmacytic infiltrate with fibrosis, and therapeutically by a dramatic response to steroids. When so defined, AIP can be sub-classified into two subtypes, 1 and 2. Recent international consensus diagnostic criteria for AIP have been developed for diagnosis of both forms of AIP. Type 1 AIP is the pancreatic manifestation of a multiorgan disease, recently named IgG4-related disease. Little is known about the pathogenesis of either form of AIP. Despite frequent association of type 1 AIP with elevated serum IgG4 levels and infiltration with IgG4-positive plasma cells, it is unlikely that IgG4 plays a pathogenic role in AIP. Type 1 AIP responds to steroids, but there needs to be consensus on treatment regimens for induction and therapeutic end points. Relapses are common, but can be reduced by long-term use of low-dose steroids. Recent reports suggest that immunomodulators (azathioprine, 6-mercaptopurine and mycophenolate mofetil), as well biological agents (the antibody to CD20, rituximab) may have a role in maintaining remission in relapsing type 1 AIP. Future studies should clarify the best management options for treatment of relapses and maintenance of remission. Type 2 AIP is a pancreas-specific disorder not associated with IgG4. It presents in younger individuals equally with obstructive jaundice and pancreatitis. The inflammatory process responds to steroid therapy; relapses are uncommon. The clinical spectrum and long-term outcomes of medically treated type 2 AIP are still being evaluated.

  10. Total photoabsorption cross section on nuclei measured in energy range 0.5-2.6 GeV; Misura della sezione d`urto di fotoassorbimento tra 0.5 e 2.6 GeV su nuclei ed analisi dei dati

    Energy Technology Data Exchange (ETDEWEB)

    Mirazita, M. [INFN, Laboratori Nazionali di Frascati, Rome (Italy)

    1998-03-01

    The total photoabsorption cross section on several nuclei has been measured in the energy range 0.5 - 2.6 GeV. Nuclear data show a significant reduction of the absorption strength with respect to the free nucleon case suggesting a shadowing effect at low energies.

  11. On the impedance of galvanic cells XXV. The double-layer capacitance of the dropping mercury electrode in 1 M HCl, 7.5 M HCl and 5.2 M HClO4 and the kinetic parameters of the hydrogen electrode reaction as a function of temperature in these solutions

    NARCIS (Netherlands)

    Dekker, B.G.; Sluyters-Rehbach, M.; Sluyters, J.H.

    The impedance of the dropping mercury electrode in aqueous solutions in 1 M HCl, 7.5 M HCl and 5.2 M HClO4, saturated with hydrogen at one atmosphere was measured at temperatures between −39° and +72° both in and outside the potential region where the electrode reaction, e+H+ H2,

  12. Completeness in Hybrid Type Theory

    DEFF Research Database (Denmark)

    Areces, Carlos; Blackburn, Patrick Rowan; Huertas, Antonia

    2014-01-01

    found in propositional and first-order hybrid logic, and (as is usual inhybrid logic) we automatically obtain a wide range of completeness results for stronger logics and languages. Our approach is deliberately low-tech. We don’t, for example, make use of Montague’s intensional type s, or Fitting......We show that basic hybridization (adding nominals and @ operators) makes it possible to give straightforward Henkin-style completeness proofs even when the modal logic being hybridized is higher-order. The key ideas are to add nominals as expressions of type t, and to extend to arbitrary types...... the way we interpret @i in propositional and first-order hybrid logic. This means: interpret @iαa , where αa is an expression of any type a , as an expression of type a that rigidly returns the value that αa receives at the i-world. The axiomatization and completeness proofs are generalizations of those...

  13. Different collagen types define two types of idiopathic epiretinal membranes

    OpenAIRE

    Kritzenberger, Michaela; Junglas, Benjamin; Framme, Carsten; Helbig, Horst; Gabel, Veit-Peter; Fuchshofer, Rudolf; Tamm, Ernst R; Hillenkamp, Jost

    2011-01-01

    Abstract Aims: To identify differences in extracellular matrix contents between idiopathic epiretinal membranes (IEM) of cellophane macular reflex (CMRM) or preretinal macular fibrosis (PMFM) type. Methods and results: IEM were analyzed by light and quantitative transmission electron microscopy, immunohistochemistry, and Western blotting. Substantial differences between CMRM and PMFM were observed regarding the nature of extracellular fibrils. In CMRM, the fibrils were thin with...

  14. Boston type I keratoprosthesis: Review.

    Science.gov (United States)

    Magalhães, Fernanda Pedreira; Sousa, Luciene Barbosa de; Oliveira, Lauro Augusto de

    2012-01-01

    Regardless of significant progress in the field of corneal transplantation to treat corneal opacification, some cases of corneal blindness still present a poor prognosis for conventional penetrating keratoplasty. In patients with repeated graft failure and/or with severe ocular surface disease, the Boston type I keratoprosthesis (type I BKPro) has become a viable option. Modifications in its design and postoperative management have improved the long-term outcomes of visual acuity, retention, and postoperative infection rates. These advances made the type I BKPro be considered a safe alternative for visual rehabilitation in many patients with corneal pathologies. However, postoperative handle of chronic comorbidities, such as glaucoma, is still critical for preserving the visual gains achieved with BKPro.

  15. Boston type I keratoprosthesis: Review

    Directory of Open Access Journals (Sweden)

    Fernanda Pedreira Magalhães

    2012-06-01

    Full Text Available Regardless of significant progress in the field of corneal transplantation to treat corneal opacification, some cases of corneal blindness still present a poor prognosis for conventional penetrating keratoplasty. In patients with repeated graft failure and/or with severe ocular surface disease, the Boston type I keratoprosthesis (type I BKPro has become a viable option. Modifications in its design and postoperative management have improved the long-term outcomes of visual acuity, retention, and postoperative infection rates. These advances made the type I BKPro be considered a safe alternative for visual rehabilitation in many patients with corneal pathologies. However, postoperative handle of chronic comorbidities, such as glaucoma, is still critical for preserving the visual gains achieved with BKPro.

  16. Glucagon and type 2 diabetes

    DEFF Research Database (Denmark)

    Lund, Asger; Bagger, Jonatan I; Christensen, Mikkel

    2014-01-01

    In normal physiology, glucagon from pancreatic alpha cells plays an important role in maintaining glucose homeostasis via its regulatory effect on hepatic glucose production. Patients with type 2 diabetes suffer from fasting and postprandial hyperglucagonemia, which stimulate hepatic glucose...... production and, thus, contribute to the hyperglycemia characterizing these patients. Although this has been known for years, research focusing on alpha cell (patho)physiology has historically been dwarfed by research on beta cells and insulin. Today the mechanisms behind type 2 diabetic hyperglucagonemia...... or antagonization of the glucagon receptor constitutes potentially effective treatment strategies for patients with type 2 diabetes. In this review, we focus on the regulation of glucagon secretion by the incretin hormones glucagon-like peptide-1 (GLP-1) and GIP. Furthermore, potential advantages and limitations...

  17. Bianchi-type string cosmology

    CERN Document Server

    Batakis, N A

    1995-01-01

    Bianchi-type string cosmology involves generalizations of the FRW backgrounds with three transitive spacelike Killing symmetries, but without any a priori assumption of isotropy in the 3D sections of homogeneity. With emphasis on those cases with diagonal metrics and vanishing cosmological constant which which have not been previously examined in the literature, the present findings allow an overview and the classification of all Bianchi-type backgrounds. These string solutions (at least to lowest order in alpha prime) offer prototypes for the study of spatial anisotropy and its impact on the dynamics of the early universe.

  18. Operational Semantics of Termination Types

    DEFF Research Database (Denmark)

    Nielson, Flemming; Nielson, Hanne Riis

    1996-01-01

    and algebraic data types. The well-founded orderings are defined by pattern matching against the definition of the algebraic data types. We prove that the analysis is semantically sound with respect to a big-step (or natural) operational semantics. We compare our approach based on operational semantics to one...... based on denotational semantics and we identify the need for extending the semantic universe with low constructs whose sole purpose is to facilitate the proof. For dealing with partial correctness it suffices to consider approximations that are less defined than the desired fixed points; for dealing...

  19. Type-2 fuzzy granular models

    CERN Document Server

    Sanchez, Mauricio A; Castro, Juan R

    2017-01-01

    In this book, a series of granular algorithms are proposed. A nature inspired granular algorithm based on Newtonian gravitational forces is proposed. A series of methods for the formation of higher-type information granules represented by Interval Type-2 Fuzzy Sets are also shown, via multiple approaches, such as Coefficient of Variation, principle of justifiable granularity, uncertainty-based information concept, and numerical evidence based. And a fuzzy granular application comparison is given as to demonstrate the differences in how uncertainty affects the performance of fuzzy information granules.

  20. Five types of organizational strategy

    DEFF Research Database (Denmark)

    Steensen, Elmer Fly

    2014-01-01

    Models in the strategy field defining the strategy concept emphasize schools of thought or strategy perspectives, but not how to define the idiosyncratic composition of an organization’s strategy content. Based on a literature review in which meanings have been attached to the concept, this paper...... presents a new model including five types of organizational strategy. The model emphasizes that key influencers may make heterogeneous contributions to an organization’s strategy and also that significant effects may result from interaction between types of strategy....