WorldWideScience

Sample records for vu106 mek-fm 2006-01

  1. Temperature, salinity and other variables collected from discrete sample and profile observations using CTD, bottle and other instruments from the KNORR in the South Pacific Ocean from 2006-01-30 to 2006-03-14 (NODC Accession 0115593)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — NODC Accession 0115593 includes chemical, discrete sample, physical and profile data collected from KNORR in the South Pacific Ocean from 2006-01-30 to 2006-03-14...

  2. AT013L01: WHOI cruise 013 leg 01 aboard the R/V Atlantis from 2006-01-17 - 2006-01-31 (NODC Accession 0041585)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Post-cruise download of raw data from shipboard computer(s) as furnished by the Woods Hole Oceanographic Institution Shipboard Scientific Support Group and archived...

  3. Multibeam collection for KN182L10: Multibeam data collected aboard Knorr from 2006-01-04 to 2006-01-25, departing from Manzanillo, Mexico and returning to Punta Arenas, Chile

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This data set is part of a larger set of data called the Multibeam Bathymetry Database (MBBDB) where other similar data can be found at...

  4. Multibeam collection for AT13: Multibeam data collected aboard Atlantis from 2006-01-18 to 2006-01-31, departing from Woods Hole, MA and returning to Woods Hole, MA

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This data set is part of a larger set of data called the Multibeam Bathymetry Database (MBBDB) where other similar data can be found at...

  5. Multibeam collection for AMAT01RR: Multibeam data collected aboard Roger Revelle from 2006-01-05 to 2006-01-17, departing from San Diego, CA and returning to Papeete, French Polynesia

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This data set is part of a larger set of data called the Multibeam Bathymetry Database (MBBDB) where other similar data can be found at...

  6. Physical and profile data collected aboard the F.G. Walton Smith during cruise WS0603 in the Gulf of Mexico and North Atlantic Ocean from 2006-01-17 to 2006-01-25 (NCEI Accession 0140561)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — NCEI Accession 0140561 includes physical and profile data collected aboard the F.G. Walton Smith during cruise WS0603 in the Gulf of Mexico and North Atlantic Ocean...

  7. Multibeam collection for TN189: Multibeam data collected aboard Thomas G. Thompson from 2006-01-21 to 2006-01-28, departing from Puerto Ayora, Ecuador and returning to Puerto Ayora, Ecuador

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This data set is part of a larger set of data called the Multibeam Bathymetry Database (MBBDB) where other similar data can be found at...

  8. CIGS Thin Film Solar Cells, phase 2 Uppsala University Final report 2006-01-01 - 2007-06-14

    Energy Technology Data Exchange (ETDEWEB)

    Edoff, Marika (Thin Film Solar Cell group, Dep. Technical Sciences, Uppsala Univ., P.O. Box 534, SE-751 21 Uppsala (Sweden)) (and others)

    2007-06-15

    The project CIGS Thin Film Solar Cells, phase 2 has been going on for 18,5 months and was interrupted in advance on the 14th of June, 2007. The decision to shorten the period was taken by the board of the Swedish Energy Agency the 14th of February. It was decided to reevaluate and re-direct the financial support to the group. A new project, CIGS Thin Film Solar Cells, phase 3, superseded this project and will go on for the initially planned project period (until 2009-12-31). During the project much of the focus has been on research on Cd-free buffer layers, with an emphasis on the interface properties between the CIGS and the buffer layer. (CIGS is a commonly used acronym for Cu(In,Ga)Se{sub 2}, which is the active absorption layer in this type of solar cells) The combination of high quality CIGS and the new buffer layers has been another field of interest. CIGS solar cell module development and computer modelling of solar cells and modules has been the third major research area. The results show that the group still holds a position as one of the leaders in the world in this field. The 18.5 % efficient Cd-free solar cell, which was obtained and independently confirmed is only one percent away from the world record and in addition it is Cd-free using a Zn(O,S) buffer layer (the world record from NREL contains Cd). By alloying ZnO with MgO instead of ZnS almost equally good results can be achieved. During the last half year an 18.1 % cell has been measured with a (Zn,Mg)O buffer layer. Solar cell module technology includes several research issues, both fundamental as e.g. modelling of cell voltage and losses as a function of distance from interconnect to interconnect, but also more development as e.g. encapsulation routines. The harsh environment test (damp heat test) run at 85 deg C and 85 % relative humidity for 1000 hours was passed for both a small (12.5x12.5 cm2) and a large (27.5x30 cm2) module within the degradation limits stated by the IEC standards, using an edge seal technology

  9. National Centers for Environmental Prediction (NCEP) Regional Ocean Forecast System (ROFS) model output from 2006-01 (NODC Accession 0002660)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Regional Ocean Forecast System (ROFS) has been developed jointly by the Ocean Modeling Branch of the National Weather Service's Environmental Modeling Center,...

  10. mos119_0601c.tif-- Side scan sonar image from survey effort HMPR-119-2006-01c in the Olympic Coast national marine sanctuary.

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This side scan sonar imagery of the sea floor (120-210 m water depths) was mosaiced from acoustic data collected in April 2006 aboard the NOAA ship McArthurII. A...

  11. mos119_0601b.tif-- Side scan sonar image from survey effort HMPR-119-2006-01b in the Olympic Coast national marine sanctuary.

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This side scan sonar imagery of the sea floor (110-310 m water depths) was mosaiced from acoustic data collected in April 2006 aboard the NOAA ship McArthurII. A...

  12. mos119_0601d.tif-- Side scan sonar image from survey effort HMPR-119-2006-01d in the Olympic Coast national marine sanctuary.

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This side scan sonar imagery of the sea floor (140-260 m water depths) was mosaiced from acoustic data collected in April 2006 aboard the NOAA ship McArthurII. A...

  13. KN182L11: WHOI cruise 182 leg 11 aboard the R/V Knorr from 2006-01-28 - 2006-03-14 (NODC Accession 0041583)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Post-cruise download of raw data from shipboard computer(s) as furnished by the Woods Hole Oceanographic Institution Shipboard Scientific Support Group and archived...

  14. mos119_0601a.tif-- Side scan sonar image from survey effort HMPR-119-2006-01a in the Olympic Coast national marine sanctuary.

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This side scan sonar imagery of the sea floor (90-270 m water depths) was mosaiced from acoustic data collected in April 2006 aboard the NOAA ship McArthurII.A Klein...

  15. Effects of Fusion Zone Size on Failure Modes and Performance of Advanced High Strength Steel Spot Welds (2006-01-0531)

    Energy Technology Data Exchange (ETDEWEB)

    Sun, Xin; Stephens, Elizabeth V.; Khaleel, Mohammad A.

    2007-03-01

    This paper examines the effects of fusion zone size on failure modes, static strength and energy absorption of resistance spot welds (RSW) of advanced high strength steels (AHSS). DP800 and TRIP800 spot welds are considered. The main failure modes for spot welds are nugget pullout and interfacial fracture. Partial interfacial fracture is also observed. The critical fusion zone sizes to ensure nugget pull-out failure mode are developed for both DP800 and TRIP800 using the limit load based analytical model and the micro-hardness measurements of the weld cross sections. Static weld strength tests using cross tension samples were performed on the joint populations with controlled fusion zone sizes. The resulted peak load and energy absorption levels associated with each failure mode were studied using statistical data analysis tools. The results in this study show that the conventional weld size of 4 t1/2 can not produce nugget pullout mode for both the DP800 and TRIP800 materials. The results also suggest that performance based spot weld acceptance criteria should be developed for different AHSS spot welds.

  16. hab119_0601a -- Habitat polygons for HMPR-119-2006-01a survey in Olympic Coast national marine sanctuary.

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Benthic habitat polygon coverages are being created for the Olympic Coast national marine sanctuary (OCNMS).ROV, towed camera sled, bathymetry data, sedimentary...

  17. Physical and meteorological data from the Scripps Institution of Oceanography (SIO) Coastal Data Information Program (CDIP) stations from 2006-01-01 to 2006-12-31 (NODC Accession 0111915)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The data contain raw and processed values concerning wave size and direction, energy spectral data (both original and processed), and, where available, sea surface...

  18. Multibeam collection for AHI-06-01: Multibeam data collected aboard Ahi from 2006-01-12 to 2006-02-04, departing from Honolulu, HI and returning to Pago Pago, American Samoa

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This data set is part of a larger set of data called the Multibeam Bathymetry Database (MBBDB) where other similar data can be found at...

  19. Physical and meteorological delayed-mode full-resolution data from the Tropical Atmosphere Ocean (TAO) array in the Equatorial Pacific from 2006-01-15 to 2008-08-11 (NODC Accession 0125936)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Tropical Atmosphere Ocean (TAO) array of moored buoys spans the tropical Pacific. Moorings within the array measure surface meteorological and upper-ocean...

  20. Temperature and salinity profile data collected from CTD casts by NOAA Ship BAY HYDROGRAPHER in the Chesapeake Bay during survey operations along the NE US coast from 2006-01-05 to 2006-08-28 (NCEI Accession 0014614)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Pressure, salinity, and temperature data were collected from CTD casts from the NOAA Survey Vessel BAY HYDROGRAPHER. Data were collected in the Chesapeake Bay from...

  1. Real-Time XBT Data assembled by US NOAA Atlantic Oceanographic Meteorological Laboratory (AOML) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted, 01/16/2006 - 01/22/2006 (NODC Accession 0002502)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — These data represent data collected from the Shipboard Environmental (data) Acquisition System (SEAS), a program developed by National Oceanic and Atmospheric...

  2. NOAA Coral Reef Watch Monthly 25 km Ocean Acidification Product Suite from 2006-01-01 to 2006-12-31 covering the Greater Caribbean Region (NCEI Accession 0075254)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The NOAA Coral Reef Watch Experimental Ocean Acidification Product Suite (OAPS) offers an important synthesis of satellite and modeled environmental datasets to...

  3. Multibeam collection for KN182L11: Multibeam data collected aboard Knorr from 2006-01-29 to 2006-03-14, departing from Punta Arenas, Chile and returning to Valparaiso, Chile

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This data set is part of a larger set of data called the Multibeam Bathymetry Database (MBBDB) where other similar data can be found at...

  4. Real-Time XBT Data assembled by US NOAA Atlantic Oceanographic Meteorological Laboratory (AOML) for the Global Temperature-Salinity Profile Program (GTSPP) and submitted, 01/23/2006 - 01/29/2006 (NODC Accession 0002513)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — These data represent data collected from the Shipboard Environmental (data) Acquisition System (SEAS), a program developed by National Oceanic and Atmospheric...

  5. Final Report for CRADA Agreement , AL-C-2006-01 with Microsens Biotechnologies: Detection of the Abnormal Prion Protein in Blood by Improving the Extraction of this Protein

    Energy Technology Data Exchange (ETDEWEB)

    Schmerr, Mary Jo

    2009-03-31

    Several conditions were examined to optimize the extraction protocol using Seprion beads for the abnormal prion protein. Different combinations of water, hexafluro-2-propanol and formic acid were used. The results of these extraction protocols showed that the magnetic beads coated with Seprion reagents were subject to degradation, themselves, when the extraction conditions that would solubilize the abnormal prion protein were used. These compounds caused interference in the immunoassay for the abnormal prion protein and rendered these protocols incompatible with the assay systems. In an attempt to overcome this problem, another approach was then used. The coated beads were used as an integral part of the assay platform. After washing away denaturing agents, the beads with the 'captured' abnormal prion were incubated directly in the immunoassay, followed by analysis by the capillary electrophoresis. When a capillary electrophoresis electro-kinetic separation was attempted, the beads disturbed the analysis making it impossible to interpret. A pressure separation method was then developed for capillary electrophoresis analysis. When 20 samples, 5 of which were positive were analyzed, the assay identified 4 of the 5 positives and had no false positives. When a larger number of samples were analyzed the results were not as good - there were false positives and false negatives. It was then observed that the amount of beads that were loaded was dependent upon how long the beads were allowed to settle before loading them into the capillary. This resulted in unacceptable variations in the results and explained that when large numbers of samples were evaluated the results were not consistent. Because the technical difficulties with using the Seprion beads could not be overcome at this time, another approach is underway that is outside of the scope of this CRADA. No further agreements have been developed. Because the results were not favorable, no manuscripts were written nor intellectual property developed.

  6. Physical profile data collected by NOAA Ship Ronald H. Brown and NOAA Ship KA'IMIMOANA during the year 2006 in the equatorial Pacific Ocean, 2006-01 to 2006-11 (NCEI Accession 0012641)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — CTD data were collected in the equatorial Pacific Ocean, during 2006, to service the TAO/TRITON array, a network of deep ocean moored buoys to support research and...

  7. Physical data collected from Seaglider SG016 during Labrador Sea, April 2005 in the Labrador Sea deployed from 2005-04-06 to 2006-01-01 (NODC Accession 0111845)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Seaglider is a buoyancy driven autonomous underwater vehicle (AUV) developed by scientists and engineers at the University of Washington's School of Oceanography and...

  8. Partial pressure (or fugacity) of carbon dioxide, salinity and other variables collected from underway - surface observations using Barometric pressure sensor, Carbon dioxide (CO2) gas analyzer and other instruments from the EXPLORER OF THE SEAS in the Caribbean Sea, Gulf of Mexico and others from 2006-01-15 to 2006-12-24 (NODC Accession 0109925)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — NODC Accession 0109925 includes biological, chemical, meteorological, physical and underway - surface data collected from EXPLORER OF THE SEAS in the Caribbean Sea,...

  9. Digital collection of photographic surveys of beach profiles and animals taken as part of the Beach Watch program at Pillar Point/Maverick's (segment 3-35), California from 2006-01-21 to 2007-04-13 (NODC Accession 0037170)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — NOAA's Gulf of the Farallones National Marine Sanctuary (GFNMS) Beach Watch Program, administered by the Farallones Marine Sanctuary Association (FMSA), is a...

  10. Dissolved inorganic carbon, alkalinity, temperature, salinity and other variables collected from discrete sample and profile observations using Alkalinity titrator, CTD and other instruments from the AURORA AUSTRALIS in the Indian Ocean from 2006-01-02 to 2006-03-12 (NODC Accession 0109922)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — NODC Accession 0109922 includes biological, chemical, discrete sample, meteorological, physical and profile data collected from AURORA AUSTRALIS in the Indian Ocean...

  11. Dissolved inorganic carbon, pH, alkalinity, temperature, salinity and other variables collected from discrete sample and profile observations using Alkalinity titrator, CTD and other instruments from the MIRAI in the East China Sea (Tung Hai), North Pacific Ocean and others from 2005-10-31 to 2006-01-30 (NODC Accession 0109919)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — NODC Accession 0109919 includes chemical, discrete sample, physical and profile data collected from MIRAI in the East China Sea (Tung Hai), North Pacific Ocean,...

  12. Dissolved inorganic carbon, pH, alkalinity, temperature, salinity and other variables collected from discrete sample and profile observations using CTD, Coulometer for DIC measurement and other instruments from the KEIFU MARU in the North Pacific Ocean, Philippine Sea and South Pacific Ocean from 2006-01-18 to 2006-02-06 (NODC Accession 0112328)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — NODC Accession 0112328 includes biological, chemical, discrete sample, physical and profile data collected from KEIFU MARU in the North Pacific Ocean, Philippine Sea...

  13. Dissolved inorganic carbon, pH, alkalinity, temperature, salinity and other variables collected from discrete sample and profile observations using CTD, Coulometer for DIC measurement and other instruments from the Ryofu Maru II in the North Pacific Ocean, Philippine Sea and South Pacific Ocean from 2006-01-13 to 2006-02-22 (NODC Accession 0112290)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — NODC Accession 0112290 includes biological, chemical, discrete sample, physical and profile data collected from Ryofu Maru II in the North Pacific Ocean, Philippine...

  14. Partial pressure (or fugacity) of carbon dioxide, salinity and other variables collected from Surface underway observations using Carbon dioxide (CO2) gas analyzer, Shower head chamber equilibrator for autonomous carbon dioxide (CO2) measurement and other instruments from LAURENCE M. GOULD in the South Atlantic Ocean, South Pacific Ocean and Southern Oceans from 2006-01-02 to 2006-12-26 (NCEI Accession 0148764)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — NCEI Accession 0148764 includes Surface underway data collected from LAURENCE M. GOULD in the South Atlantic Ocean, South Pacific Ocean and Southern Oceans (> 60...

  15. Partial pressure (or fugacity) of carbon dioxide, salinity and other variables collected from Surface underway observations using Carbon dioxide (CO2) gas analyzer, Shower head chamber equilibrator for autonomous carbon dioxide (CO2) measurement and other instruments from LAURENCE M. GOULD in the South Atlantic Ocean, South Pacific Ocean and Southern Oceans from 2006-01-01 to 2006-12-27 (NCEI Accession 0144535)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — NCEI Accession 0144535 includes Surface underway data collected from LAURENCE M. GOULD in the South Atlantic Ocean, South Pacific Ocean and Southern Oceans (> 60...

  16. 房颤并发脑栓塞50例临床分析与护理

    Institute of Scientific and Technical Information of China (English)

    付冬丽; 范波胜

    2011-01-01

    @@ 房颤患者极易发生左心房内的附壁血栓脱落,随血流进人颅内动脉,导致脑栓塞发生[1].我科2006-01~2010-05共收治房颤所致脑栓塞患者40例,经精心护理,效果满意,现报告如下.

  17. 阴式辅助腹腔镜在子宫腺肌瘤误诊为子宫肌瘤剔除术中的应用4例分析

    Institute of Scientific and Technical Information of China (English)

    姚利萍

    2011-01-01

    @@ 2006-01-2010-05我院共行腹腔镜子宫肌瘤剔除术(LM)148例,其中4例系子宫腺肌瘤术前误诊为子宫肌瘤,施行阴式辅助腹腔镜子宫腺肌瘤剔除术,效果良好,报道如下.

  18. XIAP as a Molecular Target for Therapeutic Intervention in Prostate Cancer

    Science.gov (United States)

    2006-10-01

    Molecular Cell 21, 775–785, March 17, 2006 ª2006 Elsevier Inc. DOI 10.1016/j.molcel.2006.01.033XIAP Is a Copper Binding Protein Deregulated in Wilson’s...level and activity of XIAP and provide an additional Molecular Cell 776Figure 1. Altered Expression of XIAP in Cop- per Toxicosis Disorders (A...induced to shift by the addition of cop- per was w6 hr (Figure 2B). Quantitative real-time PCR Molecular Cell 778Figure 3. The XIAP Mobility Shift Is

  19. 五瓣法联合筋膜皮瓣整复四肢蹼状瘢痕挛缩31例

    Institute of Scientific and Technical Information of China (English)

    刘文剑; 付建华

    2011-01-01

    @@ 蹼状瘢痕挛缩是整形外科常见的畸形,多见于腋窝、肘窝、腘窝及其他部位,影响肢体的外形和功能.笔者于2006-01至2010-05采用五瓣法联合筋膜皮瓣整复四肢蹼状瘢痕挛缩31例,手术简便,效果满意.

  20. 亚急性甲状腺炎48例分析

    Institute of Scientific and Technical Information of China (English)

    王浩霆

    2010-01-01

    @@ 亚急性甲状腺炎(简称亚甲炎)又称De quervain甲状腺炎,肉芽肿性甲状腺炎,巨细胞性甲状腺炎,其临床表现各异,易被误诊、漏诊.我科2006-01/2009-06共收治亚急性甲状腺炎48例,取得了满意疗效,现分析如下.

  1. 误诊为腔隙性脑梗死的脊髓型颈椎病12例分析

    Institute of Scientific and Technical Information of China (English)

    关海森; 王黎明; 范波胜

    2011-01-01

    @@ 现将我院2006-01~2011-05曾被误诊为腔隙性脑梗死的脊髓型颈椎病12例报告如下. 1 资料和方法 1.1 一般资料 本组12例患者中男7例,女5例,年龄50~75岁,平均63岁.职业:驾驶员4例,教师2例,打字员2例,行政人员2例,农民工2例,误诊时间3个月~1 a.

  2. The reconstruction principle of bone structure%骨结构的重建理念

    Institute of Scientific and Technical Information of China (English)

    张文贤; 李盛华

    2011-01-01

    背景:在骨折治疗原则上,主要体现在从生物学和机械力学两方面进行骨结构重建,把生物固定与机械固定,髓内固定与髓外固定相结合.目的:介绍骨折治疗、骨结构重建理念的发展历程和研究进展.方法:应用计算机检索中国期刊全文数据库(CNKI:2006-01/2011-05)、Pubmed数据库和Medline database(2006-01/2011-05)数据库有关骨结构的重建理念的文章,检索词分别为"骨结构,重建,理念"和"bone structure,rebuild,principle",语言分别设定为中文和英文.结果与结论:共收集30篇有关骨结构的重建理念的文章,排除重复或类似的同一研究,14篇符合综述要求.骨折的治疗理念已经由机械力学固定体系逐渐转向生物学固定体系.骨折治疗必须着重于寻求骨折稳固和软组织完整之间的一种平衡,植入物和器械设计明显改善.近年来,又出现了数字化虚拟人体技术、生物力学有限元理论、创伤控制论、骨质疏松的药理学研究、用组织工程学理论和技术修复创伤缺损等.总的来说,骨结构重建的理念就是患者为中心,在宏观与微观的层次上选择骨折治疗最合理的方法,引导和促进骨的愈合、功能恢复.%BACKGROUND: In principle, fracture treatment mainly focuses on bone remodeling from the biological and mechanical aspectsto combine mechanical fixation with biological fixation as well as combine intramedullary fixation with extramedullary fixation.OBJECTIVE: To introduce the principle development of fracture treatment and bone remodeling.METHODS: A computer-based search of CNKI (2006-01/2011-05) and PubMed (2006-01/2011-05) for bone remodelingarticles using the keywords of “bone structure, rebuild, principle” in Chinese and English, respectively.RESULTS AND CONCLUSION: In 30 collected articles, 14 were included in result analysis. The treatment concept of fractureshas been gradually changed from mechanical fixation system to

  3. 急性心肌梗死患者发病前状态与预后关系分析%Analysis of Relationship of Premorbid Condition and Prognosis of Patients with Acute Cardiac Infarction

    Institute of Scientific and Technical Information of China (English)

    李民; 赵施竹

    2007-01-01

    随机抽取本院2003-01~2006-01收治的急性心肌梗死(AMI)患者300例,探讨其对AMI患者预后的影响。1对象和方法1.1对象均有患者发病前的活动或非活动状态。诊断符合下列条件中的2条:(1)典型的胸痛或胸部不适〉30min;(2)心肌酶值超过正常上限2倍;(3)心电图新出现性Q波或有特征性ST-T改变;(4)冠状动脉造影证实。

  4. 诱导性多能干细胞在神经系统疾病中的研究与应用%Research and application of induced pluripotent stem cells in nervous system diseases

    Institute of Scientific and Technical Information of China (English)

    李家速; 姚忠祥

    2011-01-01

    BACKGROUND: Induced pluripotent stem cells (iPSCs) can differentiate into many kinds of expected neural cells to treat nervous system diseases which lack of neural cells, and play a relevant functional role. Recently, lots of encouraging progresses have been made. How to improve the efficiency and ensure graft substitute security, and be better applied to the clinical research has become a hot spot.OBJECTIVE: To review the recent research and application of iPSCs in Parkinson's disease, spinal cord injury, motor neuron disease and other nervous system diseases.METHODS: We searched PubMed database (2006-01/2010-09) using "induced pluripotent stem cells, neurological diseases" as research words, and searched the Chinese Biomedical Literature Database (2006-01/2010-09) using "induced pluripotent stem cells" as the key words.RESULTS AND CONCLUSION: A total of 149 articles on induced pluripotent stem cells were collected, including 17 Chinese articles, and 132 English articles. By reading the title and summary, articles that have nothing to do with this article and those with repetitive content were excluded. Finally, a total of 25 articles were reviewed. The iPSCs as a potential new treatment can be used as donor cells and diseases of the carrier, and have greatly potential value in Parkinson's disease, spinal cord injury, muscular atrophy motor neurons and other nervous system diseases. Basic and clinical researches have made great achievements, but induction efficiency and transplantation safety are still major obstacles to its application and development.%背景:诱导性多能干细胞可转化为各种期望的神经细胞,替代神经系统疾病损伤或缺失的神经细胞,发挥相应的功能作用,目前已经取得了可喜的进展.如何提高其诱导效率,保证移植替代的安全性,将其更好的应用到临床已成为研究热点.目的:就近年来诱导性多能干细胞在帕金森病、脊髓损伤、运动神经元病等神经系统疾病

  5. Ionosphere-Thermosphere Coupling and Energy Partitioning During Two HSS Events

    Science.gov (United States)

    Verkhoglyadova, Olga; Mannucci, Anthony; Meng, Xing; Tsurutani, Bruce; Mlynczak, Martin; Hunt, Linda; Redmon, Robert; Green, Janet

    2015-04-01

    We analyze external driving of the ionosphere-thermosphere (IT) system during two CIR-HSS events, on 29 April - 4 May 2011 and on 8-12 May 2012. By studying similar CIR-HSS events in the same phase of a solar cycle and the same season we aim to understand differences and similarities in the magnetosphere-IT coupling caused by external driving and other factors (pre-conditioning or driving from below). We focus on understanding energy and momentum transfer (with solar wind coupling functions, Joule heating, nitric oxide (NO) infrared cooling radiation and energetic particle precipitation) and corresponding energy partitioning in the IT system. We utilize observations from DMSP, POES/MEPED and TIMED/SABER. We use the Global Ionosphere-Thermosphere Model (GITM, Ridley et al., 2006) with different driving inputs to understand the IT response. We outline a physics-based approach for forecasting moderate to intense storms in the Earth's upper atmosphere caused by solar wind disturbances. Ridley, A. J., Y. Deng, and G. Toth (2006), The global ionosphere-thermosphere model, Journal of Atmospheric and Solar-Terrestrial Physics, 68(8), 839-864, doi:10.1016/j.jastp.2006.01.008.

  6. The Children's Games: The Role of Teacher in its Constitution

    Directory of Open Access Journals (Sweden)

    Graziela Pereira da Conceição

    2008-04-01

    Full Text Available This report is fruit of observations, registrations and of direct actions with the children and has as objective socializes some of our experiences and reflections as a trainee of the course of Pedagogy, semester 2006/01 of the Federal University of Santa Catarina. Our training was accomplished with the group 3B, in the period vespertino, constituted by 9 children, of the 1 year-old age group and 7 months to 2 years and 7 months, being 3 boys and 6 girls. The training had in the participant observation a road for the approach to the infantile universes, with the intention of contemplating about the organization of the daily of the children, as they link, as it works and what does in those spaces offered to them. Through written registrations and photographic we tried to build a sensitive and attentive glance to the several manners of being, of acting and of living the children's childhood inside of the institution of infantile education. These registrations allowed to know us the children's group and they orientated our roads for propositions that guaranteed the children's rights, your needs, interests, desires and wills.

  7. 碘伏与碘甘油对比治疗冠周炎的临床观察%Clinical Observation about Distinction of Therapeutic Effect in Pericoronitis Treated by Iodophors and Iodoglycerin

    Institute of Scientific and Technical Information of China (English)

    郑新

    2007-01-01

    目的 观察0.5%碘伏液与碘甘油用于智齿冠周炎治疗的临床效果.方法 选择本院口腔科2006-01~2006-12进行冠周炎治疗60例.随机分成两组,比较治疗效果.观察组(碘伏组)30例,对照组(碘甘油组)30例.结果 观察组有效率93%.轻度感染4例,中度感染23例,重度感染3例.对照组有效率73%,轻度感染7例,中度感染21例,重度感染2例.结论 0.5%碘伏液可作为冠周炎治疗首选的一种方法,在控制炎症,消除肿胀,减少分泌物方面优于碘甘油.

  8. 2006-2009年河北省城乡居民伤害监测%Surveillance of Injury Among Residents in Hebei Province, 2006-2009

    Institute of Scientific and Technical Information of China (English)

    栗华; 张中朝; 朱俊卿; 张敬一; 刘春霞; 齐静兵

    2011-01-01

    目的 了解河北省城乡居民伤害状况和危害程度,为制定有效的干预措施提供科学依据.方法 资料来源于秦皇岛市、藁城市各3家不同级别伤害监测哨点医院急诊室.对2006-01-01/2009-12-31首次就诊于哨点医院的伤害患者资料进行分析.结果 2006-01-01/2009-12-31共收集81154例伤害病例,男女性别比为2.17:1;前6位伤害病例的原因依次是机动车车祸(28.14%)、钝器伤(23.26%)、跌倒/坠落(22.25%)、刀/锐器伤(9.14%)、中毒(7.54%)和非机动车车祸(5.65%);中毒是农村老年女性的第1位伤害原因(36.84%),钝器伤是15~19岁年龄组最主要的伤害原因;溺水、窒息/悬吊、火器伤、烧烫伤和中毒造成的严重程度较重;伤害部位以头部为主;伤害发生时间有一定规律性;自残/自杀造成的伤害病例81.49%需观察或住院或转院.结论 河北省2006-2009年居民伤害以机动车车祸、钝器伤、跌倒/坠落、刀/锐器伤和中毒为主,青壮年是高发人群,应加强伤害的预防控制工作.%Objective To understand the prevalence and degree of injury among residents in urban and rural area in Hebei and provide scientific eyidence to conduct effective interventions. Methods The surveiUance was conducted among the injury patients seeking medical care for the first time in 6 hospitals in Qinhuangdao and Gaocheng from January 1,2006 to December 31 ,2009. Results Totally 81 154 injury cases were surveyed. The male to female ratio of the cases was 2. 17 : 1. The first six injuries were the traffic injury by motor vehicles (28. 14% ) , blunt injury (23. 26% ) , falling injury ( 22. 25% ) , sharp instrument injury (9. 14% ) , poisoning (7. 54% ) and the traffic injury by non - motor vehicles (5. 65) . The poisoning was the first injury cause of elderly females in rural area (36. 84% ). Blunt injury was the most important injury in age group of 15 - 19 years old. Drowning, asphyxia or hanging, gun shot, fire

  9. Application of nano-silver materials in gynecological diseases%纳米银材料在妇科疾病中的应用

    Institute of Scientific and Technical Information of China (English)

    王芳; 毛熙光

    2011-01-01

    目的:分析比较纳米银凝胶对不同程度、不同类型阴道炎及宫颈糜烂的治疗效果,及高频电波刀环切术结合纳米银与单纯高频电波刀在妇科疾病中的应用效果.方法:以 "纳米银;纳米银凝胶;阴道炎;宫颈炎"为检索词,索2006-01/2010-12相关文章.纳入与纳米银凝胶治疗阴道炎相关研究文献;排除重复研究或Meta分析类文章.以25篇文献为主进行分析.结果:纳米银凝胶是采用先进的纳米技术,单质银制成粒径约25 nm左右粒子,于其量子效应、小尺寸效应和极大的比表面积特性,于吸收,果较好.纳米银凝胶可在阴道和宫颈部位形成层保护膜,而杀灭致病微生物.可减少阴道排液及缩短阴道排液时间.结论:纳米银制剂具有安全、广谱、高效的抗菌、杀菌作用,于为患者接受,纳米银的生物安全性还有待进一步研究.%OBJECTIVE: To analyze the effects of nano-silver gel on vaginitis and cervical erosion at different levels and different types, and to compare the efficacy of LEEP combined with nano-silver and simple LEEP in treatment of gynecological diseases.METHODS: Relevant articles published in 2006-01/2010-12 were searched using "nano-silver; nano-silver gel; vaginitis;cervicitis" as keywords. Repetitive articles and Meta-analysis were excluded. Twenty-five articles were included.RESULTS: Nano-silver gel is prepared by advanced nanotechnology, about 25 nm in diameter, and characterized as quantum effect, small size effect and large su rface area, easy to be absorbed. Nano-silver gel can form a protective membrane in the vaginal and cervical parts, which can kill pathogenic microorganisms, reduce vaginal discharge and shorten the time of vaginal discharge.CONCLUSION: The nano-silver preparation is safe with broad-spectrum and highly effective antibacterial and sterilization, which is easy for patients. However, the biological safety of nano-silver has yet needed further studies.

  10. Rehabilitative treatment of aphasia: study and application%失语症的康复治疗:研究与应用

    Institute of Scientific and Technical Information of China (English)

    孙会芳; 倪朝民

    2006-01-01

    目的:探讨失语症的言语语言治疗、药物治疗和影响治疗效果的因素.资料来源:应用计算机检索Pubmed数据库2000-01/2006-01期间的有关失语症方面的文献.检索词为"aphasia,anomia,treat,treatment,therapy,cure,heal",并限定文章语言种类为English.同时计算机检索CNKI 2000-01/2006-01期间的有关失语症方面的文献.检索词为"失语,治疗",并限定文章语言种类为中文.资料选择:共检索300余篇文献进行筛选.以近3年内研究内容相关且发表在权威杂志上的文章优先,选择了以失语症治疗为主要研究内容的文献24篇.资料提炼:将资料进行分类,其中19篇是关于言语语言治疗的文献,5篇是关于药物治疗的文献.资料综合:言语语言治疗和药物治疗是治疗失语症的主要方法.言语语言治疗主要包括刺激法、阻断去除法、认知心理学的方法、计算机辅助治疗和小组治疗等.但言语语言治疗的有效性尚有争议.药物治疗主要有溴隐停、右苯丙胺、吡拉西坦和中药治疗等.药物治疗虽对失语的恢复有帮助,但治疗机制还不确切.影响失语症恢复的因素很多,发病时失语的严重程度是最主要的因素,失语症的类型,患者的职业,受教育程度,及社会支持等都对言语的恢复有影响.结论:①失语症的治疗强度与其康复效果有关系.要选择合理的治疗方法还需进一步的研究.②药物治疗的效果虽已被证明有效,但适用范围广、副作用小的药物开发还有待于进一步的研究.③治疗时需要综合考虑可能影响康复效果的各种因素来制定个性化的治疗方案.

  11. Coupled THMC modelling of single fractures in novaculite and granite for DECOVALEX-2015

    Science.gov (United States)

    Bond, A.; Chittenden, N.; Fedors, R. W.; Lang, P. S.; McDermott, C.; Neretnieks, I. E.; Pan, P.; Šembara, J.; Brusky, I.; Watanabe, N.; Lu, R.; Yasuhara, H.

    2015-12-01

    topography. References [1] doi:10.1016/j.epsl.2006.01.046 [2] doi:10.1016/j.apgeochem.2011.07.005

  12. CERES BiDirectional Scans (BDS) data in HDF (CER_BDS_Aqua-FM3_Edition2)

    Science.gov (United States)

    Wielicki, Bruce A. (Principal Investigator)

    Each BiDirectional Scans (BDS) data product contains twenty-four hours of Level-1b data for each CERES scanner instrument mounted on each spacecraft. The BDS includes samples taken in normal and short Earth scan elevation profiles in both fixed and rotating azimuth scan modes (including space, internal calibration, and solar calibration views). The BDS contains Level-0 raw (unconverted) science and instrument data as well as the geolocated converted science and instrument data. The BDS contains additional data not found in the Level-0 input file, including converted satellite position and velocity data, celestial data, converted digital status data, and parameters used in the radiance count conversion equations. The following CERES BDS data sets are currently available: CER_BDS_TRMM-PFM_Edition1 CER_BDS_Terra-FM1_Edition1 CER_BDS_Terra-FM2_Edition1 CER_BDS_Terra-FM1_Edition2 CER_BDS_Terra-FM2_Edition2 CER_BDS_Aqua-FM3_Edition1 CER_BDS_Aqua-FM4_Edition1 CER_BDS_Aqua-FM3_Edition2 CER_BDS_Aqua-FM4_Edition2 CER_BDS_Aqua-FM3_Edition1-CV CER_BDS_Aqua-FM4_Edition1-CV CER_BDS_Terra-FM1_Edition1-CV CER_BDS_Terra-FM2_Edition1-CV. [Location=GLOBAL] [Temporal_Coverage: Start_Date=1997-12-27; Stop_Date=2006-01-01] [Spatial_Coverage: Southernmost_Latitude=-90; Northernmost_Latitude=90; Westernmost_Longitude=-180; Easternmost_Longitude=180] [Data_Resolution: Temporal_Resolution=1 day; Temporal_Resolution_Range=Daily - < Weekly].

  13. CERES BiDirectional Scans (BDS) data in HDF (CER_BDS_Terra-FM1_Edition2)

    Science.gov (United States)

    Wielicki, Bruce A. (Principal Investigator)

    Each BiDirectional Scans (BDS) data product contains twenty-four hours of Level-1b data for each CERES scanner instrument mounted on each spacecraft. The BDS includes samples taken in normal and short Earth scan elevation profiles in both fixed and rotating azimuth scan modes (including space, internal calibration, and solar calibration views). The BDS contains Level-0 raw (unconverted) science and instrument data as well as the geolocated converted science and instrument data. The BDS contains additional data not found in the Level-0 input file, including converted satellite position and velocity data, celestial data, converted digital status data, and parameters used in the radiance count conversion equations. The following CERES BDS data sets are currently available: CER_BDS_TRMM-PFM_Edition1 CER_BDS_Terra-FM1_Edition1 CER_BDS_Terra-FM2_Edition1 CER_BDS_Terra-FM1_Edition2 CER_BDS_Terra-FM2_Edition2 CER_BDS_Aqua-FM3_Edition1 CER_BDS_Aqua-FM4_Edition1 CER_BDS_Aqua-FM3_Edition2 CER_BDS_Aqua-FM4_Edition2 CER_BDS_Aqua-FM3_Edition1-CV CER_BDS_Aqua-FM4_Edition1-CV CER_BDS_Terra-FM1_Edition1-CV CER_BDS_Terra-FM2_Edition1-CV. [Location=GLOBAL] [Temporal_Coverage: Start_Date=1997-12-27; Stop_Date=2006-01-01] [Spatial_Coverage: Southernmost_Latitude=-90; Northernmost_Latitude=90; Westernmost_Longitude=-180; Easternmost_Longitude=180] [Data_Resolution: Temporal_Resolution=1 day; Temporal_Resolution_Range=Daily - < Weekly].

  14. CERES BiDirectional Scans (BDS) data in HDF (CER_BDS_Terra-FM2_Edition2)

    Science.gov (United States)

    Wielicki, Bruce A. (Principal Investigator)

    Each BiDirectional Scans (BDS) data product contains twenty-four hours of Level-1b data for each CERES scanner instrument mounted on each spacecraft. The BDS includes samples taken in normal and short Earth scan elevation profiles in both fixed and rotating azimuth scan modes (including space, internal calibration, and solar calibration views). The BDS contains Level-0 raw (unconverted) science and instrument data as well as the geolocated converted science and instrument data. The BDS contains additional data not found in the Level-0 input file, including converted satellite position and velocity data, celestial data, converted digital status data, and parameters used in the radiance count conversion equations. The following CERES BDS data sets are currently available: CER_BDS_TRMM-PFM_Edition1 CER_BDS_Terra-FM1_Edition1 CER_BDS_Terra-FM2_Edition1 CER_BDS_Terra-FM1_Edition2 CER_BDS_Terra-FM2_Edition2 CER_BDS_Aqua-FM3_Edition1 CER_BDS_Aqua-FM4_Edition1 CER_BDS_Aqua-FM3_Edition2 CER_BDS_Aqua-FM4_Edition2 CER_BDS_Aqua-FM3_Edition1-CV CER_BDS_Aqua-FM4_Edition1-CV CER_BDS_Terra-FM1_Edition1-CV CER_BDS_Terra-FM2_Edition1-CV. [Location=GLOBAL] [Temporal_Coverage: Start_Date=1997-12-27; Stop_Date=2006-01-01] [Spatial_Coverage: Southernmost_Latitude=-90; Northernmost_Latitude=90; Westernmost_Longitude=-180; Easternmost_Longitude=180] [Data_Resolution: Temporal_Resolution=1 day; Temporal_Resolution_Range=Daily - < Weekly].

  15. Chiropractic with new theoretical system for vertebral disease rehabilitation%美式脊椎矫正学为脊椎疾病康复干预注入新的内容与活力

    Institute of Scientific and Technical Information of China (English)

    郭明; 董安立; 刘芳龄

    2007-01-01

    目的:阐述美式脊椎矫正学(Chiropractic)的发展史与现状,从人体健康的平衡观、整体观及脊椎、脊柱的力学结构方面介绍脊椎矫正学的理论体系.方法:查阅关于美式脊椎矫正学的国外3部著作,同时检索2002-10/2006-01中国期刊全文网关于美式脊椎矫正学的相关文献,检索词为"美式脊椎矫正".结果:脊椎矫正学的主要目标是针对人体脊椎功能异常和/或与神经系统的关系,找出并恢复位移异常的脊椎,去除对神经系统的影响,使身体回到健康自然的状态.其主要治疗特点是针对性强,无创伤,无痛苦,疗效显著,安全系数高,是绿色疗法、纯自然疗法.结论:脊椎矫正学从人体健康的平衡观、整体观出发,对脊椎、脊柱的力学结构进一步重新认识,从而对脊椎、脊柱常见病、多发病已经形成了自己独到的理论体系,以及相应的诊疗方法,这些理论和方法过去和现在已经被越来越多的临床实践所证实.

  16. Effects of intracameral cefuroxime injection on the prophylaxis of endophthalmitis after cataract surgeries:a Meta-analysis%前房内注入头孢呋辛预防白内障术后眼内炎的Meta分析

    Institute of Scientific and Technical Information of China (English)

    吴晓玉; 蒋林志

    2015-01-01

    AIM: To evaluate the effects of intracameral cefuroxime injection on the prophylaxis of postoperative endophthalmitis after cataract surgeries, and compare endophthalmitis conditions between intracameral cefuroxime injection group and no intervention control group, using Meta analysis to search literatures at home and abroad. METHODS: By searching through Pubmed, the Cochrane Library, EMBASE, QVIP, CNKI, Wanfang, the literatures published from January 1 st 2006 to January 31 rd 2015 were collected. The data in five literatures about the effects of intracameral cefuroxime injection on the prophylaxis of endophthalmitis after cataract surgeries were analyzed. By extracting data, incidence of endophthalmitis after cataract surgeries with taking the preventive measures or not taking was compared by Review Manager 5. 2. Adopting fixed effect model, values of odds ratio ( OR) and 95% Confidence Interval ( 95% CI ) were recorded and compared, analyzed sensitivity analysis, excluded heterogeneity and calculated outcomes. RESULTS: After comparing the incidence of endophthalmitis from intracameral cefuroxime injection group and control group, the result was statistically significant [OR=0. 11 (P  方法:检索国内外数据库如 Pubmed、The Cochrane Library、EMBASE、维普中文科技期刊数据库、中国知网、万方数据库经审稿人审核发表选取2006-01-01/2015-01-31的关于前房内注入头孢呋辛与对照组无干预措施对白内障术后眼内炎预防作用的文章,共纳入5篇文献,通过提取数据,观察采取与未采取该预防措施后白内障术后眼内炎的发病率,应用Review Manager 5.2软件,采用固定效应模型,统计比较OR值和95%CI,进行敏感性分析,排除异质性,得出结果。  结果:Meta分析比较前房内注入头孢呋辛与对照组,以白内障术后眼内炎的发病率作为指标,统计结果差异有明显的统计学意义( OR=0.11,95%CI=0.07~0.18,P  结论:前房内注入

  17. Clinical observation of orbicularis muscle shortening improved treatment for senile entropion%眼轮匝肌缩短改良术治疗老年性下眼睑内翻的疗效观察

    Institute of Scientific and Technical Information of China (English)

    张小战; 李鹏

    2014-01-01

    To analyze the clinical results of orbicularis muscle shortening surgery and eyelid skin orbicularis muscle resection for senile entropion. ●METHODS: From January 01, 2006 to December 31, 2012, senile patients with lower eyelid were divided into two groups according to different surgical methods. Group A with the orbicularis muscle shortening improved operation in 20 cases (38 eyes), group B used the eyelid skin orbicularis muscle resection in 21 cases (36 eyes). The effects of surgery were followed-up postoperatively. ●RESULTS: Patients were followed up for 1 - 2a, 20 patients ( 38 eyes ) in group A were cured without recurrence; 7 eyes recurred in group B, the recurrence rate was 19%, the recurrence rate after surgery both groups were statistically significant (P ●CONCLUSlON: The effect of orbicularis muscle shortening improved operation for senile entropion is good and stable.%目的:分析比较眼轮匝肌缩短改良术和眼睑皮肤轮匝肌切除术治疗老年性下睑内翻的临床效果。  方法:对2006-01-01/2012-12-31收治的老年性下睑内翻患者,按手术方法不同分为两组:A 组采用眼轮匝肌缩短改良术,20例38眼;B 组采用眼睑皮肤轮匝肌切除术,21例36眼。术后坚持随访,观察术后效果。  结果:术后随访1~2a,A 组20例38眼均治愈,未见复发;B 组治愈16例29眼,治愈率81%,未愈5例7眼,未愈率19%,复发7眼,复发率19%,两组手术后治愈率、未愈率、复发率的差异均具有统计学意义(P  结论:对于老年性下睑内翻患者行眼轮匝肌缩短改良矫治手术,治疗效果良好稳定。

  18. 糖尿病患者应用临床护理路径的效果评价

    Institute of Scientific and Technical Information of China (English)

    曹利琴; 冯志香; 崔麟

    2008-01-01

    随着糖尿病(D iabetes m ellitus,DM)发病率的不断上升,作为一种慢性全身性疾病,患者对疾病的态度及其对治疗的经过认识对DM的控制有极大影响。临床护理路径是一种制定好的计划,它的功能是用图表的形式提供有时间和有效的照顾,使治疗、护理有序,减少漏项,缩短住院时间,提高护理质量。糖尿病教育是一切治疗的基础[1]。借鉴美国护理学者在护理管理模式中应用临床路径对患者实施整体护理的做法[2],我们老年病科对40例DM患者应用临床护理路径进行管理,效果较好,现总结如下。表1两组DM患者接受健康教育后的效果比较(x-±s)组别平均住院天数(d)平均住院费用(元)患者满意度(分)血糖(mmol/L)(空腹)(餐后)路径组(n=40)9.04±2.88 2 832.63±788.61 10.65±1.50 6.17±5.17 6.80±4.57对照组(n=40)13.68±4.16b3 815.22±1 862.76b7.83±1.45b7.46±1.53 7.56±2.67 bP<0.01vs路径组1资料与方法1.1对象:2004-01~2006-01,在我科确诊的80例DM患者随机分为两组,路径组40例,...

  19. Past changes of landscape due to increased dynamics of erosion processes in the Bezděz-Doksy region (Czech Republic)

    Science.gov (United States)

    Vysloužilová, Barbora; Dreslerová, Dagmar; Kozáková, Radka; Poništiak, Štefan; Chuman, Tomáš; Šefrna, Luděk

    2016-04-01

    . Quantifying prehistoric soil erosion - A review of soil loss methods and their application to a Celtic square enclosure (Viereckschanze) in Southern Germany. Geoarchaeology 22, 873-889. doi:10.1002/gea.20199 Peeters, I., Rommens, T., Verstraeten, G., Govers, G., Van Rompaey, A., Poesen, J., Van Oost, K., 2006. Reconstructing ancient topography through erosion modelling. Geomorphology 78, 250-264. doi:10.1016/j.geomorph.2006.01.033

  20. CERES Single Satellite Footprint, TOA and Surface Fluxes, Clouds (SSF) data in HDF (CER_SSF_Aqua-FM3-MODIS_Edition2A)

    Science.gov (United States)

    Wielicki, Bruce A. (Principal Investigator)

    _Date=2006-01-01] [Spatial_Coverage: Southernmost_Latitude=-90; Northernmost_Latitude=90; Westernmost_Longitude=-180; Easternmost_Longitude=180] [Data_Resolution: Temporal_Resolution=1 hour; Temporal_Resolution_Range=Hourly - < Daily].

  1. CERES ERBE-like Instantaneous TOA Estimates (ES-8) in HDF (CER_ES8_Terra-FM2_Edition2)

    Science.gov (United States)

    Wielicki, Bruce A. (Principal Investigator)

    The ES-8 archival data product contains a 24-hour, single-satellite, instantaneous view of scanner fluxes at the top-of-atmosphere (TOA) reduced from spacecraft altitude unfiltered radiances using Earth Radiation Budget Experiment (ERBE) scanner Inversion algorithms and the ERBE shortwave (SW) and longwave (LW) Angular Distribution Models (ADMs). The ES-8 also includes the total (TOT), SW, LW, and window (WN) channel radiometric data; SW, LW, and WN unfiltered radiance values; and the ERBE scene identification for each measurement. These data are organized according to the CERES 3.3-second scan into 6.6-second records. As long as there is one valid scanner measurement within a record, the ES-8 record will be generated. The following CERES ES8 data sets are currently available: CER_ES8_TRMM-PFM_Edition1 CER_ES8_TRMM-PFM_Edition2 CER_ES8_TRMM-PFM_Transient-Ops2 CER_ES8_Terra-FM1_Edition1 CER_ES8_Terra-FM2_Edition1 CER_ES8_Terra-FM1_Edition2 CER_ES8_Terra-FM2_Edition2 CER_ES8_Aqua-FM3_Edition1 CER_ES8_Aqua-FM4_Edition1 CER_ES8_Aqua-FM3_Edition2 CER_ES8_Aqua-FM4_Edition2 CER_ES8_Aqua-FM3_Edition1-CV CER_ES8_Aqua-FM4_Edition1-CV CER_ES8_Terra-FM1_Edition1-CV CER_ES8_Terra-FM1_Edition1-CV. [Location=GLOBAL] [Temporal_Coverage: Start_Date=1997-12-27; Stop_Date=2006-01-01] [Spatial_Coverage: Southernmost_Latitude=-90; Northernmost_Latitude=90; Westernmost_Longitude=-180; Easternmost_Longitude=180] [Data_Resolution: Temporal_Resolution=1 day; Temporal_Resolution_Range=Daily - < Weekly].

  2. CERES ERBE-like Instantaneous TOA Estimates (ES-8) in HDF (CER_ES8_Terra-FM1_Edition2)

    Science.gov (United States)

    Wielicki, Bruce A. (Principal Investigator)

    The ES-8 archival data product contains a 24-hour, single-satellite, instantaneous view of scanner fluxes at the top-of-atmosphere (TOA) reduced from spacecraft altitude unfiltered radiances using Earth Radiation Budget Experiment (ERBE) scanner Inversion algorithms and the ERBE shortwave (SW) and longwave (LW) Angular Distribution Models (ADMs). The ES-8 also includes the total (TOT), SW, LW, and window (WN) channel radiometric data; SW, LW, and WN unfiltered radiance values; and the ERBE scene identification for each measurement. These data are organized according to the CERES 3.3-second scan into 6.6-second records. As long as there is one valid scanner measurement within a record, the ES-8 record will be generated. The following CERES ES8 data sets are currently available: CER_ES8_TRMM-PFM_Edition1 CER_ES8_TRMM-PFM_Edition2 CER_ES8_TRMM-PFM_Transient-Ops2 CER_ES8_Terra-FM1_Edition1 CER_ES8_Terra-FM2_Edition1 CER_ES8_Terra-FM1_Edition2 CER_ES8_Terra-FM2_Edition2 CER_ES8_Aqua-FM3_Edition1 CER_ES8_Aqua-FM4_Edition1 CER_ES8_Aqua-FM3_Edition2 CER_ES8_Aqua-FM4_Edition2 CER_ES8_Aqua-FM3_Edition1-CV CER_ES8_Aqua-FM4_Edition1-CV CER_ES8_Terra-FM1_Edition1-CV CER_ES8_Terra-FM1_Edition1-CV. [Location=GLOBAL] [Temporal_Coverage: Start_Date=1997-12-27; Stop_Date=2006-01-01] [Spatial_Coverage: Southernmost_Latitude=-90; Northernmost_Latitude=90; Westernmost_Longitude=-180; Easternmost_Longitude=180] [Data_Resolution: Temporal_Resolution=1 day; Temporal_Resolution_Range=Daily - < Weekly].

  3. CERES Single Satellite Footprint, TOA and Surface Fluxes, Clouds (SSF) data in HDF (CER_SSF_Aqua-FM4-MODIS_Ed2A-NoSW)

    Science.gov (United States)

    Wielicki, Bruce A. (Principal Investigator)

    _Date=2006-01-01] [Spatial_Coverage: Southernmost_Latitude=-90; Northernmost_Latitude=90; Westernmost_Longitude=-180; Easternmost_Longitude=180] [Data_Resolution: Temporal_Resolution=1 hour; Temporal_Resolution_Range=Hourly - < Daily].

  4. Neurotransmitters and neural stem cell differentiation%神经递质与神经干细胞分化

    Institute of Scientific and Technical Information of China (English)

    王立君; 姚晓辉

    2008-01-01

    学术背景:干细胞的自我更新、增殖和分化主要依赖于周围特殊的微环境.神经递质不仅介导神经元之间和神经元与效应器之间的信息传递,其作为细胞外环境中的一员,也参与神经干细胞的增殖与分化.目的:深入认识几种重要的神经递质对神经干细胞分化的影响.检索策略:由该论文的研究人员应用计算机榆索Pubmed数据库1998-01/2006-01的相关文献,检索词"nerval stem cells,differentiation,neurotransimitters",并限定文章语言种类为English.同时计算机检索中国期刊全文数据库1998-01/2006-01的相关文献,检索词"神经干细胞,分化,神经递质",并限定文章语言种类为中文.共榆索到94篇文献,对资料进行初审,纳入标准:①文章所述内容应与神经递质及神经干细胞分化密切相关.②同一领域选择近期发表或在权威杂志上发表的文章.排除标准:①重复性研究.②Meta分析.文献评价:文献的来源主要是通过对神经递质在神经干细胞分化中的重要作用进行汇总分析.所选用的30篇文献中,1篇为综述,其余均为临床或基础实验研究.资料综合:神经递质是神经元合成的化学物质,起着传导信息的作用.谷氨酸作为中枢神经系统一种主要的兴奋性递质,对突触信息的传递和贮存、突触可塑性的形成和维持产生重要影响.氨基丁酸是脑内含量较高的抑制性神经递质.介导大约30%~40%中枢神经系统神经元的功能,此外还具有自分泌/旁分泌功能.乙酰胆碱可通过激活α-7样烟碱乙酰胆碱受体导致原代培养新生大鼠嗅球细胞神经突起过度生长.一氧化氮广泛参与神经细胞的存活、分化和可塑性的发生.在成体脊髓、脑干和一些脑区.甘氨酸受体通过突触后细胞膜Cl通透性而起到突触后抑制作用.结论:神经递质作为细胞"微环境"的一部分,与神经干细胞的分化密切

  5. Research on mitochondrial DNA mutations and clinical feature of suspected leber hereditary optic neuropathy%疑似LHON患者mtDNA突变规律及临床研究

    Institute of Scientific and Technical Information of China (English)

    解世朋; 石慧君; 常永业; 王浩; 张铭连

    2013-01-01

    目的:研究临床疑似Leber遗传性视神经病变(Leber's hereditary optic neuropathy,LHON)患者的mtDNA突变规律及临床表现.方法:对2006-01/2012-01就诊于邢台市眼科医院符合病例入选标准的175例患者,按是否有家族史分为对照组及观察组,对照组患者口服维生素B1片、甲钴胺片治疗,观察组患者加用注射用甲泼尼龙琥珀酸钠,对两组患者抽取静脉血,进行mtDNA 11778,3460,14484三个原发突变位点及相关突变热点进行检测,分析其发病年龄、突变率、突变位点、logMAR最佳矫正视力.结果:观察组:男78例,女34例,年龄8~42(平均23±4.5)岁,mtDNA突变阴性者59例(52.7%),mtDNA突变阳性者53例(47.3%),其中G11778A突变41例(36.6%),T14484C突变5例(4.5%),G3460A 突变2例(1.8%),另外尚有G15927A突变1例,A15951G突变1例,G11696A突变1例,G11778A+G11696A突变 1例,G11778A+G3316A突变1例.mtDNA突变阴性者平均logMAR视力为1.11±0.31.对照组:男46例,女17例,年龄7~44(平均18±6.5)岁,G11778突变53例(84.1%),T14484C突变8例(12.7%),G3460A突变2例(3.2%),平均logMAR视力为1.13±0.32.结论:疑似LHON患者发病年龄较LHON患者偏大,mtDNA突变G11778A占多数,存在多个mtDNA同时突变及其它mtDNA位点突变;对糖皮质激素治疗不敏感,最佳矫正logMAR视力在1.1左右.

  6. Follow-up of the posterior cruciate ligament injury treated by arthroscopic reconstruction of ligament advanced reinforcement system%LARS人工韧带关节镜下移植治疗膝关节后交叉韧带损伤的随访效果分析

    Institute of Scientific and Technical Information of China (English)

    吴宇黎; 吴海山; 李晓华; 钱齐荣

    2007-01-01

    目的:观察经关节镜下行LARS(ligament advanced reinforcement system)人工韧带移植重建膝关节后交叉韧带损伤患者膝关节功能的治疗结果.方法:选择2004-08/2006-01在上海长征医院骨科关节外科因膝关节后交叉韧带损伤行关节镜下LARS人工韧带重建手术的患者15例,均为运动损伤,所有患者均知情同意.全部病例予以LARS人工韧带(法国LARS公司制造,型号:PPLY 110)进行后交叉韧带重建或加强手术,LARS人工韧带的主要材料为高韧性的聚酯纤维(聚对苯二甲酸乙二醇脂),组织相容性好,由于其特殊的编制方式,胶原纤维和血管内皮细胞可长入其中.术后静脉常规使用抗生素1 d,返回病房后即开始使用CPM机予以被动活动,术后3 d扶拐下地行走,2个月时恢复正常的活动或体育训练.术后1,2,6,12,24个月随访,检查膝关节的稳定程度、活动范围及疼痛部位.按Lysholm膝关节评分系统评估膝关节功能,满分为100分,84分以上为膝关节功能正常,66~84分为尚可,低于65分较差.结果:15例患者全部进入结果分析,无脱落.①15例患者随访6~24个月,其中6~12个月10例,12~18个月2例,18~24个月3例,平均11个月.所有患膝不稳定症状消失,关节功能良好,伸屈度0°~(130±10.2)°.所有病例均于术后2个月左右恢复正常体育活动,无急慢性滑膜炎出现.②患者术后末次随访时的Lysholm膝关节评分显著高于术前(85.5±2.33,45.2±1.23,t=9.547,P<0.01).结论:LARS人工韧带具有以下特点:①适用于术后早期康复干预,早期自主运动者.②术后膝关节功能恢复快.③无并发症出现,组织相容性好.④为运动性损伤膝关节后交叉韧带损伤重建较为理想和安全的移植材料.

  7. Endoscopic posterior cruciate ligament reconstruction using achilles tendon allografts: single-bundle versus double-bundle%关节镜下异体跟腱单双束重建后交叉韧带的随机对照

    Institute of Scientific and Technical Information of China (English)

    张其亮; 滕学仁

    2011-01-01

    ligament reconstruction and its long-term effects need to be further investigated.%背景:关节镜下重建后交叉韧带主要有单束重建和双束重建两种方式.目的:随机对比应用异体跟腱单双束重建后交叉韧带损伤的临床疗效.方法:选择青岛市市立医院骨科2006-01/2009-01的后交叉韧带损伤患者共70例,随机分为单束重建组和双束重建组,分别行异体跟腱单束重建及双束重建.结果与结论:术后顺利完成康复计划并获得随访的病例共52例.双束重建组手术时间较单束重建组长,行关节腔穿刺的病例数较单束重建组多(P 0.05).说明与单束重建比较,双束重建后的早期临床疗效无明显提高,且双束重建的手术创伤大,手术时间长,术后关节肿胀重,故不推荐作为首选手术方式,其远期疗效优待进一步观察.

  8. 干细胞移植治疗脊髓损伤的研究进展%Advances of stem cells transplantation for spinal cord injury

    Institute of Scientific and Technical Information of China (English)

    刘长路; 吴岩

    2011-01-01

    背景:干细胞移植作为治疗脊髓损伤最具前景的方法,已经在大量的动物实验和临床试验中得到证实.目的:综述干细胞移植治疗脊髓损伤的相关研究进展.方法:应用计算机检索2006-01/2010-12中国知网、Medline数据库相关文章,中文检索词"干细胞,脊髓损伤,细胞移植",英文检索词"stem cells,spinal cord injury,cells transplantation",共检索到文献494篇,最终纳入符合标准的文献24篇.结果与结论:研究发现,移植的干细胞可以在脊髓内迁移、分化为神经元并分泌神经营养物质,促进神经组织的修复,改善神经功能.胚胎干细胞最早用于治疗脊髓损伤,但潜在的致瘤性等成为其临床应用的障碍;神经干细胞理论上是治疗脊髓损伤的首选干细胞,由于分离纯化技术要求严格,费用昂贵等使其在研究中进展缓慢;骨髓间充质干细胞来源丰富、取材方便,可行自体移植,避开了伦理学和移植后排斥等问题,目前被认为是一种理想的自体干细胞移植来源.随着细胞联合移植、基因修饰及组织工程支架移植治疗脊髓损伤的研究不断取得进展,许旺细胞、嗅鞘细胞的应用范围和治疗效果也得到提升.%BACKGROUND: Stem cell transplantation as the most promising treatment for spinal cord injury, has been confirmed in a large number of animal experiments and clinical trials. OBJECTIVE: To review the related research progress of stem cell transplantation for spinal cord injury. METHORDS: A computer-based online search of related articles were performed in CNKI and Medline database published from January 2006 to December 2010, with the key words of “Stem cells; Spinal cord injury; Cells transplantation” in Chinese and English, respectively. 494 articles were collected, and 24 were included. RESULTS AND CONCLUSION: Studies show that transplanted cells can migrate, differentiate into neurons and secrete neural nutrients to promote nerve

  9. 发展中国家教学医院的白内障手术服务%Cataract surgery services in a teaching hospital in a developing country

    Institute of Scientific and Technical Information of China (English)

    Ifeoma R Ezegwui

    2009-01-01

    目的:总结发展中国家教学医院的白内障手术现状,探讨怎样在减少白内障致盲率方面达到视觉2020计划的目标.方法:通过计算机化白内障手术病例表收集从2006-01/12期间在我院手术的成人白内障病例资料.不包括外伤性白内障.应用SSPS 11.0版本分析数据.结果:在研究期间,3名眼科医生对67眼实施白内障手术.囊外白内障摘除联合后房人工晶状体植入术占95.5%.12wk随访期间,74.5%患者的最好视力为6/6-6/18,13.7%<6/18- 6/60,11.8%<6/60.结论:在尼日利亚这样的发展中国家的教学医院中,白内障手术的比率很低.这就需要提高大多数眼科医生工作的教学医院的白内障手术服务.在教学医院中实施的白内障手术应该是低成本或免费的.大量的手术是很好的锻炼,将带来好的效果.%AIM: To review the cataract surgery services in a teaching hospital in a developing country with a view to assessing how a teaching hospital can contribute to achieving the goals of the Vision 2020 programme with respect to decreasing cataract blindness.METHODS: The computerised cataract surgery record form was used to collect data on adult cataract surgery performed at Enugu State University of Sciences and Technology (ESUT) Teaching Hospital Parklane, Enugu, Nigeria over a 12 month-period (from January 2006 to December 2006). Traumatic cataracts were excluded. Data was analyzed using SSPS version 11.0.RESULTS: A total of 67 eyes had cataract operation during the study period. Three ophthalmologists did these. Majority (95.5%) had ab-externo extracapsular cataract extraction with posterior chamber intraocular lens implanted (ECCE + PC-IOL). At 12 weeks of follow up post operatively, 74.5% had best corrected vision of 6/6-6/18, 13.7% had <6/18-6/60 while 11.8% had <6/60. CONCLUSION: The volume of cataract surgeries performed in a teaching hospital in a developing country like Nigeria is low. There is need for improved service

  10. Research progress on induced efficiency and methods of induced pluripotent stem cells%诱导性多能干细胞诱导效率和方法的研究进展

    Institute of Scientific and Technical Information of China (English)

    张恩欢; 胡智兴; 李玛琳

    2011-01-01

    背景:将多能性基因导入人或动物成体细胞内,使其重编程为具有发育多潜能的干细胞,这类细胞被称为诱导性多潜能干细胞或诱导性多能干细胞.目前,有关诱导性多能干细胞的研究进展非常迅速.目的:综述诱导性多能干细胞在转化效率及优化诱导方法等方面的研究进展.方法:应用计算机检索Medline数据库(http://www.ncbi.nlm.nih.gov/Pubmed),检索时间范围为2006-01/2010-07,检索词为"induced pluripotent stem cells",限定文章语言为English.共检索1 831篇文献,选用其中57篇进行综述.结果与结论:诱导性多能干细胞的研究对生命科学产生了十分重大而深远的影响,成为干细胞领域新的研究热点,并在细胞重编程机制、诱导效率的提高、诱导方法的改进、细胞来源的扩大及向功能细胞的分化等方面取得了许多重要的进展.这些研究成果为最终的诱导性多能干细胞技术应用于临床细胞替代治疗奠定基础.%BACKGROUND: Induced pluripotent stem cells (iPS) is a type of pluripotent stem cell artificially derived from human or animal adult somatic cells which were transfected with certain pluripotency genes. At present, the researches on induced pluripotent stem cells have made great progresses. OBJECTIVE: to review the research progress in the conversion efficiency and optimization of induction methods in iPS cells. METHODS: A computer-based online search of Medline database (http://www.ncbi.nlm.nih.gov/Pubmed) from January 2006 to July 2010 was performed with the key words of “induced pluripotent stem cells” in English. The literatures were limited to English language. totally 1 831 literatures were retrieved, 57 documents of which were involved for summarization. RESULTS AND CONCLUSION: The researches on iPS cells have a great and far-reaching impact on life science, which makes it become a hot issue in stem cell field. And some rapid progresses have been made in i

  11. Stem cell transplantation for treating ischemic stroke%干细胞移植在缺血性脑卒中治疗中的应用

    Institute of Scientific and Technical Information of China (English)

    陈娟

    2012-01-01

    BACKGROUND: Ischemic cenebrovascular disease is a serious hazard to human health, which can not be treated effectively at present. How to promote recovery of impaired neural functions for patients with ischemic cerebrovascular disease is the study focus.OBJECTIVE: To explore the literature data trends in the study of stem cell transplantation for treating ischemic stroke by using search and the depth of analysis capabilities of CNKI database.DESIGN: Bibliometric data analysisDATA RETRIEVAL: A search of related literature of stem cell transplantation for treating ischemic stroke was performed in CNKI database using the key words of "stem cells" "transplantation" and "cerebral ischemia" during 2006-01 to 2011-12. The retrieval results were analyzed, and the trends were described in words and graphics.SELECTION CRITERIA: Inclusive criteria: Basic research and clinical application of stem cell transplantation for treating ischemic stroke. Exclusive criteria: (1) Literature has nothing to do with the purpose of this review. (2) Duplicated research literature. (3) Journal's own information. (4) Unpublished papers. (5) The article needs to be retrieved by phone or manual searches. (6) Year book.MAIN OUTCOME MEASUREMENTS: The literatures were analyzed by published year, literature number, subject category, research institutions, source journals, literature citations, literature download frequency, associated literature, distribution of the author, distribution of the funding and major keywords. Additionally, the stem cells from different sources were compared in treating ischemic stroke.RESULTS: A total of 231 research literatures related to stem cell transplantation for treating ischemic stroke were retrieved in CNKI during 2006 to 2011. The number of papers was fluctuated in the past 6 years. Most literatures were published in 2007 and 2009. Bone marrow mesenchymal stem cells, neural stem cells, and amniotic mesenchymal stem cells are the major cells in the study

  12. Space motion sickness: The sensory motor controls and cardiovascular correlation

    Science.gov (United States)

    Souvestre, Philippe A.; Blaber, Andrew P.; Landrock, Clinton K.

    impacts on core regulatory sensory motor and cognitive mechanisms. Static postural analysis provides specific central neurophysiological markers that can reliably identify PDS occurrence among classic peripheral musculoskeletal and spinal data [C. Landrock, P.A. Souvestre, Static postural analysis: a methodology to assess gravity related sensory motor controls' status for astronauts, 2006-01-2298, 36th SAE-ICES]. Many astronauts experience PFOI and recent research has implicated altered autonomic cardiovascular regulation caused by microgravity. HRV measurements have been used to determine if some pre-flight autonomic indicators relating to PFOI may exist by differentiating parasympathetic and sympathetic activity. ResultsThis review suggests a new approach to SMS mitigation based on specific neurophysiological assessment criteria. While SMS may not be a "unique diagnosis", it should be treated as result, or symptom of, the condition space adaptation syndrome (SAS), which can be shown to be a unique diagnosis. This methodology can identify and measure brain functional status in specific areas during pre-flight and post-flight examinations. This could provide further understanding on why, how and when SMS and PFOI might occur in Astronauts, and lead to criteria that predict susceptibility to SMS. An additional test component is presented that relates to using static central sensory-motor data towards understanding SMS and OI occurrence. Recent investigations indicate relationship between HRV autonomic indicators with Motion Sickness [B. Cheung, K. Hoffer, R. Heskin, A. Smith, Physiological and behavioral responses to an exposure to pitch illusion in the simulator, Aviation Space, 2004; Y. Yokota, M. Aoki, K. Mizuta, Y. Ito, N. Isu, Motion sickness susceptibility associated with visually induced postural instability and cardiac autonomic responses in healthy subjects, Acta Oto-laryngological, 2005]. It is found that astronauts with lower sympatho-vagal balance and higher

  13. 普通外科3种生物材料国际发展态势:基于汤森路透Web of Science数据库的文献计量结果分析%International development trends of three kinds of biological materials used in general surgery: A bibliometric analysis based on Web of Science database

    Institute of Scientific and Technical Information of China (English)

    李洪秀; 李航宇; 赵作伟; 鞠培新; 朴仁京; 南今娘

    2012-01-01

    损组织、器官或增进其功能的新型材料,己成为研究人工器官和医疗器械的基础学科.目的:对普通外科3 大类生物材料,即腹壁修复材料、缝合材料以及止血材料进行文献计量学分析,评估该领域学术文献的总体趋势,为在该领域进行深入研究提供参考.设计:不同检索式的文献计量学分析.资料提取:以"surgery(普通外科),patch(补片),suture material(缝合材料),hemostasis material OR hemostatic material OR hemostasia material(止血材料)"为关键词,检索汤森路透Web of Science数据库2006-01/2010-12 的相关文献,将分析结果及资料导出,以文字和图表的形式描述.学科类别中选择普通外科,将结果导出并分析.纳入标准:纳入研究原著、综述、技术进展、会议录、编者的信和社论;排除会议摘要、书本章节、新闻、需手工检索和电话检索的文献.主要数据的判定指标:以相关文献的国家地区分布,基金资助情况,文献类型分析,高被引文章分析,发表年份分布,发文量较多的机构分析为结果分析判定指标.结果:Web of Science 数据库收录的关于普通外科生物材料的文献中,以补片材料为主,文献量1 302 篇.在补片材料、缝合材料和止血材料的研究中以美国的发文量最多,分别为395 篇、199 篇和144 篇.而中国在这3 个领域的研究在国际上有重要地位.结论:近几年来生物材料的研究趋于成熟,发文量稳定并且呈逐渐上升趋势,补片材料是目前生物材料领域研究的热点.

  14. Shallow Moho with aseismic upper crust and deep Moho with seismic lower crust beneath the Japanese Islands obtained by seismic tomography using data from dense seismic network

    Science.gov (United States)

    Matsubara, Makoto; Obara, Kazushige

    2015-04-01

    subduction in southwest Japan. Science 296, 1679-1681. Shiomi, K., K. Obara, and H. Sato (2006) Moho depth variation beneath southwestern Japan revealed from the velocity structure based on receiver function inversion , Tectonophysics, 420, 205-221, doi:10.1016/j.tecto.2006.01.017. Shiomi, K., M. Matsubara, Y. Ito, and K. Obara (2008) Simple relationship between seismic activity along Philippine Sea slab and geometry of oceanic Moho beneath southwest Japan, Geophys. J. Int., 173, 1018-1029.

  15. Effects of Ni-Cr based porcelain-fused-to-metal crown on periodontal tissue%镍铬合金烤瓷冠修复对牙周组织的影响

    Institute of Scientific and Technical Information of China (English)

    李榕卿; 阚洪霞; 郑宗富

    2009-01-01

    depth, sulcus bleeding index, and levels of C reactive protein and tumor necrosis factor-α were significantly greater in affected teeth than in control teeth (P < 0.05).CONCLUSION: Ni-Cr alloy PFM crown produces some harmful effects on periodontal tissue.%背景:随着金属烤瓷技术的出现,镍铬合金成为应用最广泛的非贵金属类金属烤瓷用航?镍铬合金烤瓷冠金属边缘主要与牙龈接触,因此它对牙周组织可能有一定影响.目的:了解镍铬合金烤瓷冠对患牙牙周组织的影响.设计、时间及地点:回顾性病例分析,病例来自2006-01/2007-01解放军南京军区福州总院四七六临床部口腔科.对象:采用镍铬合金烤瓷冠进行上颌切牙修复的患者19例,共23颗患牙,年龄(32.5±10.8)岁.选择健康的对侧同名牙作为对照.方法:所有临床操作均由同一位医生进行,在修复体制作过程中,严格遵守口腔修复原则.常规牙体预备,排龈线排龈,均为唇侧龈下肩台0.5 mm,圆凹形肩台厚度为0.5 mm.硅橡胶印模材取模,制作临时冠.全冠制作时,尽量恢复其正常的生理解剖外形,牙冠轴面突度的增加不超过0.2 mm.永久件粘结.主要观察指标:在镍铬合金烤瓷冠戴入6~9个月后复诊,进行牙周临床检查,分别采集患牙及对照牙的龈沟液并定量,在实验室对龈沟液中的C-反应蛋白和肿瘤坏死因子α水平进行检测.结果:符合临床合格要求的镍铬合金烤瓷冠修复后,患牙的菌斑指数没有明显改变,但龈沟液量、探诊深度、龈沟内出血指数、龉狄耗贑-反应蛋白和肿瘤坏死因子α水平明显高于健康牙(P<0.05).结论:镍铬合金烤瓷冠对患牙的牙周组织有一定的不良影响.

  16. Nano-hydroxyapatite/collagen composited with recombinant human bone morphogenetic protein-2 and titanium membrane in repairing peripheral bone defects of instant dental implants%胶原基纳米骨复合重组人骨形成蛋白2及钛膜修复即刻钛种植体周围骨缺损

    Institute of Scientific and Technical Information of China (English)

    刘冰; 陈鹏; 王忠义; 柯杰; 李晓华; 汪正文

    2009-01-01

    bone to Ti implant were investigated by radiography,bone density measurement and histological examinations.RESULTS:All the bone wounds were full of new bone at 12 weeks,the Ti implants were steady and the osseointegration was good.In the nHAC+rhBMP-2 and nHAC+rhBMP-2+Ti membrane groups,new bone formed and maturated earlier.In the nHAC +Ti membrane,blank control,and nHAC + rhBMP-2 +Ti membrane groups,new bone formed well below Ti membrane and the alveolar crest was plump.In the nHAC + rhBMP-2 +Ti membrane group,new bone formed earliest with the most quantity and the alveolar crest was the plumpest.By 12 weeks,the bone density had achieved the same level as the autologous cancellous bone transplantation,but the alveolar crest was plumper compared to the positive control group.In addition,bone mass was much more.Bone formed slowest in the blank control group and fastest in the positive control group with the crest of ridge being slightly absorbed.CONCLUSION:nHAC is a new good bone graft material in repairing peripheral bone defects of instant implant,especially compositing with rhBMP-2 and/or Ti membrane.A round method to repair the surrounding bone defect of instant implant should be selected according to the specific situation in the clinic.%背景:影响即刻种植术成功的主要因素是种植体大小、形状往往与拔牙创不相适合,不能形成种植体与拔牙创的紧密接触,解决这一影响因素的方法多采用诱导骨再生膜技术或应用植骨材料.目的:观察胶原基纳米骨(nanohydroxyapatite/collogen,nHAC)复合重组入骨形成蚩白2(recombinant human bone morphogenetic protein-2,rhBMP-2)及钛膜修复即刻钛种植体周围骨缺损的效果.设计、时间及地点:随机对照动物实验,于2005-01/2006-01在解放军第四军医大学中心实验室完成.材料:宝鸡有色金属研究院提供的纯钛材料制成直径2mm,长10mm,螺距0.4mm,带自攻式螺纹的钉状螺旋种植体,无穿龈部分.西安中邦钛

  17. ATX-LPA生物学功能及其在乳腺癌中的研究进展%Biological function of ATX-LPA axis and its progress in cancer

    Institute of Scientific and Technical Information of China (English)

    邵营波; 刘慧

    2015-01-01

    OBJECTIVE To summarize the recent advances in the biological function of ATX-LPA axis and its association with breast cancer.METHODS The PubMed and CNKI database from Jan.2006 to Apr.2014 were filtered by search teams " breast cancer,autotaxin,lysophosphatidic acid".Exclusion criteria:non breast cancer and non ATX-LPA.Inclusion criterion:Recent literature about the biological function of ATX-LPA axis.Latest advances regards to some of the key findings of ATX-LPA signalling axis in breast cancer.Totally 45 literatures were enrolled in the study according to the criterions.RESULTS The ATX-LPA signaling axis acts on a series of high-affinity cell surface G protein-coupled receptors (GPCRs),leading to diverse biological actions.Many subsequent studies have combined to establish an important function for the ATX-LPA axis in mammary tumourigenesis,metastasis and drug resistance,suggesting that the ATX-LPA signalling axis is a novel target in breast cancer.The focus of researches now turn to understanding the mechanisms by which ATX and LPA promote mammary tumourigenesis,metastasis and and drug resistance.Researches about the inhibitors and monoclonal antibodies in the above-mentioned mechanisms have achieved some improvements in laboratory and clinical studies.CONCLUSIONS The biological function of ATX-LPA signaling axis in mammary tumourigenesis,metastasis and drug resistance has been confirmed,more laboratory studies are needed to provide powerful evidence to clarify detailed mechanism between ATX-LPA signaling axis and breast cancer.Targeting the ATX-LPA signalling axis for drug development may further improve the outcomes in patients of breast cancer.%目的 总结近年来关于自分泌运动因子-溶血磷脂酸(autotaxin-lysophosphatidic acid,ATX-LPA)生物学功能及其在乳腺癌中的研究进展.方法 应用PubMed和CNKI期刊全文数据库检索系统,以“乳腺肿瘤、自分泌运动因子、溶血磷脂酸”为关键词,检索2006-01-2014-04

  18. Proteinuria in patients with primary aldosteronism%原发性醛固酮增多症患者蛋白尿情况分析

    Institute of Scientific and Technical Information of China (English)

    李南方; 马轩; 王红梅; 李娟; 王新国

    2013-01-01

    目的 调查原发性醛固酮增多症(PA)与原发性高血压(EH)患者蛋白尿检出率的差异,并分析PA患者蛋白尿可能的危险因素.方法 收集新疆维吾尔自治区人民医院高血压中心2006-01-2010-01因临床特征高度怀疑为PA,且排除睡眠呼吸暂停综合征、嗜铬细胞瘤等其他类型继发性高血压并行24 h尿蛋白定量检测的患者401例.患者均经坐位肾素活性及醛固酮测定并计算血浆醛固酮与肾素活性比值(ARR)初筛、盐水负荷试验或卡托普利试验这一诊断流程,最终确诊PA患者155例为PA组,排除PA患者246例为EH组.分析两组尿蛋白、蛋白尿检出率的差异,并采用多元线性回归模型分析PA患者蛋白尿可能的危险因素.结果 与EH患者相比,PA患者的24 h尿蛋白[(1.99±0.37)比(1.85±0.34)g/24 h,P<0.01]、蛋白尿的检出率(14.2%比6.5%,P=0.01)明显增高.进一步用Logistic模型校正年龄、性别及高血压病程后,PA患者蛋白尿检出率仍然高于高血压患者(P=0.031),且PA患者蛋白尿的风险增高(OR 2.152).在PA患者中,校正年龄、高血压病程、血压及血浆肾素活性后,血浆醛固酮是蛋白尿的危险因素(β=0.232,P=0.021).结论 PA患者尿蛋白及蛋白尿检出率较高,增高的醛固酮是其主要致病因素.%Objective To study the proteinuria detection rate in patients with primary aldosteronism (PA) and essential hypertension (EH) , and to explore the possible risk factors for proteinuria in patients with PA. Methods From the hypertension department of People's Hospital of Xinjiang Uygur Autonomous Region between January 2006 and January 2010, a total of 401 inpatients were selected, who were highly suspected of PA without sleep apnea syndrome, pheochromocytoma or any other secondary hypertension. All the subjects underwent 24-hour urinary protein quantitative detection, serum aldosterone concentration and plasma renin activity (PRA) detection at the sitting position

  19. Comparison of Serum Zinc and Copper levels in Children and adolescents with Intractable and Controlled Epilepsy

    Directory of Open Access Journals (Sweden)

    Zeynab KHERADMAND

    2014-07-01

    -Melegy N. Blood levels of trace elements, electrolytes, and oxidative stress/antioxidant systems in epileptic patients. J Pharmacol Sci 2004;96:465-473.Dudek FE. Zinc and epileptogenesis. Epilepsy Curr 2001; 1:66-70.Mathie A, Sutton GL, Clarke CE, Veale EL. Zinc and copper: pharmacological probes and endogenous  modulators of neuronal excitability. Pharmacol Ther. 2006;111(3:567-83. Epub 2006/01/18.Schrauzer GN. Selenomethionine and Selenium Yeast: Appropriate Forms of Selenium for Use in Infant Formulas and Nutritional Supplements. Journal of medicinal food 1998;1(3:201-6.Seven M, Basaran SY, Cengiz M, Unal S. Deficiency of selenium and zinc as a causative factor For idiopathic intractable epilepsy. Epilepsy Research 2013;104 :35-39.

  20. Metal-to-metal hip surface arthroplasty in 63 cases A follow-up assessment%金属对金属髋关节表面置换63例随访评价

    Institute of Scientific and Technical Information of China (English)

    徐卫东; 陈刚; 李甲; 徐凌; 梁志民

    2008-01-01

    involved in the follow-up. There were no cases of dislocation, deep venous embolism, deep infection or neurovascular complications that required further treatment. The mean Harris score was 38 points before operation and significantly increased to 90 points after operation. Two patients appeared a 2-mm crevice below acetabular prostheses, which disappeared 6 months after arthroplasty. Acetabular or femoral prostheses removal, or local osteolysis was detectable.CONCLUSION: Metal-on-metal hip surface arthroplasty has excellent early effects on young and active patients. The arthroplasty potentially offers the ultimate bone preservation and better restoration of hip articulation function in patients, without specific biocompatibility.%背景:随着制作假体T艺和于术技术的改进,髋关节表面置换后假体早期松动和股骨颈骨折等情况很少发生,能得到更佳的髋关节活动功能.目的:观察髋关节表面置换后材料与宿主的生物相容性及髋关节功能恢复情况.设计、时间及地点:回顾性病例分析,于2006-01/2007-08在解放军第二军医大学长海医院骨科进行.对象:52例髋关节疾病患者完成63侧髋关节表面置换,其中11例患者做了一期双侧置换.女25例,男27例,平均年龄47.6岁.方法:假体由Zimmer公司提供,髋关节以标准4mm厚非骨水泥型髋臼(金属臼杯厚3.7mm,外覆0.3mm等离子钛涂层)进行重建.髋臼杯是大直径、半圆形(165°),外覆等离子钛涂层用以非骨水泥固定.采用后外侧入路,髋臼假体均放置在髋关节解剖中心的位置,且覆盖髋臼假体面积超过90%以上.主要观察指标:①记录置换后脱位、感染等材料与宿主的生物相容性反应.②置换后1,3,6,12个月及其后每年一次采用Harris髋关节评分系统进行功能评估.③影像学资料按照DeLee和Charnley描述的区域,记录髋臼杯周围厚度>1mm的放射线可透区.结果:①所有患者均得到随访,没有发生脱位、没

  1. Comparison of knee joint function following total knee arthroplasty with fixed platform versus rotating platform high-flexion prostheses%人工膝关节固定平台高屈曲假体与旋转平台高屈曲假体置换后膝关节功能的比较

    Institute of Scientific and Technical Information of China (English)

    刘军; 曹建刚; 田孟强; 王磊; 孙云波

    2008-01-01

    背景:膝关节假体早期设计的目的是为了改善膝关节患者的严霞疼痛.随着假体设计的不断改进,已经出现了具有良好屈曲功能的高屈曲膝关节假体.目的:比较应用固定平台高屈曲假体与旋转平台高屈曲假体行全膝关节置换后临床疗效的差异.设计:以患者为研究对象的非随机化同期对照观察.对象:2006-01/12在天津市人民医院骨关节科接受全膝关节置换的34例重度骨性关节炎患者(50膝).方法:34例患者巾16例(25膝)接受固定平台高屈曲膝假体置换,所用假体为美国捷迈公司提供LPS flexion假体;18例(25膝)接受旋转平台高屈曲膝假体置换术,所用假体为美国强生公司提供PFC sigma RPF假体.主要观察指标:对患者术前、术后两周、术后1,3,6个月的膝关竹功能按HSS评分标准进行评分,并观察术后6个月膝关节屈曲度.结果:34例均完成治疗和6个月的随访.旋转平台高屈曲假体组术后2周膝关节HSS评分高于固定平台高屈曲假体组(尸0.05).术后6个月膝关节屈曲度两组比较无显著差异[(130.4±15.2)°vs(129.9±13.8)°,P>0.05].结论:固定平台高屈曲假体与旋转平台高屈曲假体行全膝关节置换治疗重度膝关节骨性关节炎的早期疗效基本相同.%BACKGROUND:Early knee ioint prosthesis is used to relieve severe pain of patients.With continuous modification,the knee joint prosthesis with high flexion has developed.OBJECTIVE:To compare the clinical outcome between fixed platform high—flexion prosthesis and rotating platform high-flexion prosthesis following total knee arthroplasty.DESIGN:Non-randomized concurrent control trial of patients.PARTICIPANTS:Thirty-four patients(50 knees)with severe osteoarthritis underwent total knee replacement in Department of Bone and Joint,Tianjin Union Medicine Center from January to December 2006.METHODS:Of 34 patients,16(25 knees)underwent fixed platform high

  2. 胚胎肝干细胞癌变实验%Potential of carcinogenesis from hepatic progenitor cells in hepatocellular carcinoma

    Institute of Scientific and Technical Information of China (English)

    吴昌雄; 郑进方; 粱力建

    2009-01-01

    groups (P > 0.05). About 17.1% of HCCs stained positively for SRY and none of CCCs was positive for SRY in the experimental group. Most of the SRY-positive HCCs expressed GST-P and alpha-fetoprotein, but did not expressed cytokeratin 19. All of CCCs expressed cytokeratin 19 in the cytoplasm, but did not expressed GST-P and alpha-fetoprotein. CONCLUSION: Hepatic progenitor cells have malignant potential in the diethylnitrosamine model of hepatocarcinogenesis, and maintain the immature characteristics of embryonic hepatic stem cells, and still express glutathione-S-transferase and alpha-fetoprotein.%背景:目前针对肝癌是起源于成熟肝细胞的去分化还是肝干细胞的成熟受阻这一问题仍存在争议.目的:观察胚胎肝干细胞癌变的可能性.设计、时间和地点:随机对照动物实验,于2006-01/12在中山大学动物实验中心完成.材料:6~8周龄BALB/c雌性小鼠70只,体质量20~25 g,随机分为3组:空白对照组10只、模型组30只、实验组30只.另取孕14 d胎鼠用于制备胚胎肝细胞.方法:3组小鼠麻醉后均行2/3肝切除.模型组诱导肝癌,在饮水中加入100 μg/L二乙基亚硝胺,连续饮用12周.实验组在诱导肝癌的基础上行肝干细胞移植,即分离的胚胎肝细胞经肠系膜静脉注射到肝脏,每只小鼠移植1×106个细胞.空白对照组仅行肝干细胞移植,同时饮正常水.6个月后处死小鼠,制备肝脏标本,取肝癌结节做连续切片进行指标检测.主要观察指标:采用免疫组化或免疫荧光方法检测Y染色体性别决定区域蛋白、甲胎蛋白、胎盘型谷胱苷肽转移酶或细胞角蛋白19的表达,以分析肝癌的细胞来源和特征.结果:6个月后,实验组有8只小鼠成功诱癌,其中7只为肝细胞性肝癌,1只为胆管细胞性肝癌;模型组有7只小鼠成功诱癌,其中6只为肝细胞性肝癌,1只为胆管细胞性肝癌;两组诱癌率、肿瘤病理类型比较均无明显差异(P>0.05).实验组17

  3. 腺相关病毒介导转化生长因子β1和血管内皮生长因子联合转染促进糖尿病溃疡愈合的生物学效应%Biological effects of co-transfection of transforming growth factor beta 1 and vascular endothelial growth factor mediated by adeno-associated virus on promoting the dermal ulcer healing in diabetes mellitus

    Institute of Scientific and Technical Information of China (English)

    赛佳明; 张慧琴

    2006-01-01

    背景:糖尿病患者溃疡创面难愈合,目前认为是由糖尿病患者创面微循环障碍以及内源性生长因子含量降低等因素所造成.目的:观察腺相关病毒介导转化生长因子β1(AAV-TGFβ1)和血管内皮生长因子(AAV-VEGF)联合转基因治疗促进糖尿病皮肤溃疡愈合的生物学效应.设计:随机对照动物实验.单位:青岛大学医学院和青岛大学医学院附属医院.材料:实验于2004-07/2006-01在青岛大学医学院附属医院妇科实验室进行.选用成年健康大白兔24只,单纯随机分为联合转基因组和对照组各12只.方法:①采用耳缘静脉注入四氧嘧啶(130 mg/kg)建立糖尿病模型,并通过手术方法建立溃疡创面.②联合转基因组创面局部浸润注射AAV-TGFβ1和AAV-VEGF(9×106/mL病毒颗粒);对照组注射生理盐水.主要观察指标:①术后1个月,通过聚合酶链反应检测愈合组织中转化生长因子β1和血管内皮生长因子基因的转录水平.(②术后3周,用微循环显微镜计数创缘毛细血管密度值.③术后6个月通过蛋白凝胶电泳和半干电转移法对Ⅰ、Ⅲ型胶原进行分离及免疫印迹检测.④术后1 d,1,2,3周,1,2,3,4,5,6个月时测定溃疡愈合组织中胶原含量.⑤术后观测创面愈合厚度、颜色、质地.结果:24只兔全部进入结果分析.①联合转基因组转化生长因子β1和血管内皮生长因子基因转录表达增多.②联合转基因组创缘毛细血管密度值高于对照组[(19.18±3.56),(6.43±1.52)个/mm2,P<0.05].③联合转基因组愈合组织中胶原含量均增多(P<0.05),而且Ⅰ型和Ⅲ型胶原构成比中Ⅰ型胶原的比例增加.④在转染后1 d,联合转基因组与对照组溃疡愈合组织中的胶原含量接近(P>0.05).此后,联合转基因组胶原含量均高于对照组(P<0.05).⑤对照组溃疡愈合明显滞后,愈合质量差.结论:AAV-TGFβ1和AAV-VEGF可联合高效转染糖尿病兔耳皮肤溃疡创面,

  4. 兔骨髓源单个核细胞诱导血管内皮祖细胞修复尿道缺损%Bone marrow mononuclear cells-differentiated vascular endothelial progenitor cells for urethral defect repair in rabbits

    Institute of Scientific and Technical Information of China (English)

    张谦; 单岩; 李泸平; 范应中; 王家祥

    2008-01-01

    surgery,paraffin sections of urethral tissue were made.MAIN OUTCOME MEASURES: Identification of cellular morphology; vascular regeneration of urethral tissue after urethral defect repair.RESULTS: After surgery,rabbit bone marrow mononuclear cells adhesively grew in vitro.Four days later,these cells exhibited rapid clone-like growth.Ten days later,they had typical slabstone-like change,presenting with strip-shaped and bundle-shaped growth.The phenotype of cultured cells gradually turned from CD34+/CD 133+/CD31+ to CD34+/CD 1337CD31+.At weeks 4 and 12 after surgery,the number of regenerate,d blood capillaries in the urethral tissue was significantly greater in the EPC repair group than in the model group (t=-9.034 to 5.985,P < 0.01).CONCLUSION: Rabbit bone marrow mononuclear cells-differentiated EPCs can apparently improve local blood circulation in the urethral defect repair.%背景:如何解决尿道替代修复材料来源和改善新尿道的血液供应已成为尿道修复与重建研究的瓶颈问题.目的:观察血管内皮祖细胞对尿道缺损修复后改善新尿道组织血液循环的效果.设计、时间及地点:组织工程体内实验,于2006-01/2008-02在郑州大学第一附属医院外总实验室完成.材料:3~5月龄雄性日本大耳白兔13只,1只用于制各骨髓源单个核细胞,剩余12只随机分为细胞修复组8只,模型组4只.方法:无菌抽取兔两侧髂前上嵴骨髓,Percoll法贴壁分离培养单个核细胞,加入含VEGF、bFGF的培养基进行体外诱导分化,待细胞长满培养瓶底后胰蛋白酶消化传代.两组兔均建立尿道缺损模型,将脱细胞处理的无菌新鲜人羊膜修剪成1 cm2 置于尿道缺损处,用0/6DG线将其两端分别与尿道残端连续缝合,形成抹道.细胞修复组将传至第3代的兔骨髓源单个核细胞浓度调整至1010 L-1,注射于新尿道两端的吻合口处,每处0.1 mL,0/6DG线间断缝合皮下组织覆盖成形后的尿道,并在近吻合口处和新

  5. 汉族人群血管紧张素转换酶基因插入/缺失(I/D)的遗传多态性%Genetic polymorphism of angiotensin-converting enzyme gene insertion/deletion in Chinese Han population

    Institute of Scientific and Technical Information of China (English)

    高纯; 顾国浩; 夏正

    2006-01-01

    lost 287-base pair Alu repeat sequence. ②The frequencies of genotype Ⅱ, ID and DD were 46.1%, 41.5% and 12.4% respectively, with an allelic frequency of 66.8% for allele Ⅰ and 33.2% for allele D. ③The distribution of ACE genotype was similar between Japanese and Han nationality crowd, both presenting that type Ⅱ was commonly seen and type DD was the least; ID was mostly found in European and American crowd, but Ⅱ was little found. There was racial diversify of frequency of the distribution of ACE genotype among individuals of Han nationality and Japanese as well as Europeans and Americans. Compared with other nationalities, allele Ⅰ of individuals of Han nationality was significantly higher than that of above nationalities (χ2=105.55,P < 0.01), but allele D was obviously lower (χ2=87.54,P < 0.01). CONCLUSION: ACE gene polymorphism has racial diversify. To know genetic features of ACE gene polymorphism of individuals of different na tionalities is the basis and prerequisite to study the correlation of ACE gene I/D polymorphism with diseases.%背景:血管紧张素转换酶是肾素-血管紧张素-醛固酮系统的重要组成部分,血管紧张素转换酶基因第16内含子内存在一个287 bp的Alu序列的插入/缺失(I/D)多态性,与心血管疾病、IgA肾病等疾病的发生具有一定的相关性.目的:分析汉族人群血管紧张素转换酶基因插入/缺失(I/D)多态性的分布,并与已知的其他种族人群进行比较.设计:以健康汉族人为观察对象的观察性实验.单位:江苏省临床免疫学重点实验室,苏州大学附属第一医院检验科,江苏大学医学技术学院检验系.对象:受检者为2005-12/2006-01 苏州大学附属第一医院门诊健康体检者241名,男152名,女89名,平均年龄(27±8)岁,均为无血缘关系的苏州地区汉族人,经临床及实验室检查确认排除肝、肾、内分泌、心脑血管疾病.方法:应用聚合酶链反应检测了241名汉族

  6. Effect of retaining articular capsule in total hip arthroplasty through posterior approach on hip stability%经后侧入路人工全髋关节置换保留关节囊对关节稳定性的影响

    Institute of Scientific and Technical Information of China (English)

    吴慧敏; 何爱咏

    2008-01-01

    : Operation time, bleeding volume and hip dislocation after THA. RESULTS: The operation time and bleeding volume were lower in the retaining group than in the routine group (P < 0.05). After THA, hip dislocation did not occur in any patients in the retaining group but occur in 2 patients (6.2%) in the routine group. Statistical tests could not be performed due to less data, resulting in no statistical significance.CONCLUSION: There has been no precise conclusion about the effects of retaining articular capsule or not on hip stability.But retaining articular capsule shortens operation time, reduces intrao-perative bleeding, unable raise operation risk, and re-establishes hip soft tissue balance.%背景:关节囊韧带能够引导关节面的正常运动和限制过度运动的作用,尤为重要的是阻止任何非生理的位移发牛,足稳定髋关节的重要静力结构.既往认为在人工全髋关节置换中应该常规切除关节囊.目的:观察后侧入路人工全髋关节置换过程中保留关节囊结构维持关节稳定性的影响.设计、时间及地点:病例对照实验,2005-01/2006-12在中南大学湘雅二医院骨科住院行人工全髋关节置换治疗61例股骨颈骨折患者的回顾性分析.对象:2006-01/12行人工全髋关节置换保留修复关节囊的29例患者为保留组.2005-01/12行人工全髋关节置换常规切除部分关节囊的32例患者为常规组.两组患者在病例选择,假体选择项目上基线一致,术后处理一致.方法:股骨近端大转子上钻4个孔.用1-0可吸收缝线把上半部分关节囊瓣和原关节囊前上方部分缝合后,再与股骨颁基底部作褥式缝合,缝线暂不打结:另一缝线同样将关节囊瓣下半部分与原关节囊前下方部分缝合后于股骨颈基底下办两个骨孔穿出,外旋下肢.打结缝线,冉修补被切断的外旋肌群.缝合前后可以缓慢屈髋90°和全伸膝位股骨内旋45°,体会关节囊缝合后对加强关节后方稳定的

  7. 红外线对慢性萎缩性胃炎大鼠治疗作用的研究%Effects of infrared rays on chronic atrophic gastritis in rats

    Institute of Scientific and Technical Information of China (English)

    邵雪辉; 王建国; 杨跃平; 戴洁; 薄爱华

    2008-01-01

    钠为干燥粉剂批号为890720,北京市芳草医药化工研制公司生产,使用蒸馏水配制药物.红外线灯(220 V、200 W)由河北北方学院设备科购买.方法: 实验于2005-06/2006-01在河北北方学院实验中心(省级实验室)完成.①实验干预:大鼠常规标准颗粒饲料饲养1周后,其中8只作为正常对照组,其余动物进行造模, 即采用水杨酸钠、乙醇灌胃,刺激大鼠胃黏膜,并结合劳累、饥饱失常等多因素方法连续造模8周,建立慢性萎缩性胃炎大鼠模型.随机取5只进行胃黏膜病理组织学检查,确认模型成功后,将造模动物随机分成非治疗组及红外线治疗组,每组11只.红外线治疗组用220 V,200 W的红外线灯,波长0.76~1.5 μm,垂直照射大鼠胃部投影区,1次/d,10 min/次,连续照射20 d.非治疗组及正常对照组常规饲养.②实验评估:大鼠造模后1,4,9,12周进行体质量检测,并在光镜下观察各组大鼠胃黏膜的炎细胞浸润及胃黏膜厚度变化.主要观察指标:①大鼠体质量变化. ②胃黏膜病理组织学观察结果.结果: 纳入大鼠30只均进入结果分析.①大鼠体质量变化:造模大鼠从第4周末开始,非治疗组及红外线治疗组体质量增长百分率较正常对照组逐渐下降,差异有显著学意义(P < 0.05).②胃黏膜病理组织学观察结果:非治疗组大鼠胃黏膜变薄,光镜下可见胃黏膜层腺体萎缩,炎细胞浸润,部分标本伴有肠上皮化生.红外线治疗组大鼠胃黏膜明显厚于非治疗组,差异有显著性意义(P < 0.01),炎细胞少于非治疗组,差异有显著性意义(P < 0.05),细胞形态、结构、体积均恢复或接近正常.结论:红外线治疗可减轻慢性萎缩性胃炎模型大鼠胃黏膜变薄及炎细胞浸润,并有一定的治疗效果.

  8. 情感障碍患者关联性负变实验观察%A contingent negative variation study in patients with affective disorder

    Institute of Scientific and Technical Information of China (English)

    路英智; 宗文斌; 任清涛; 蒲金玉

    2006-01-01

    背景:关联性负变是与精神医学和心理学关系最为密切的一种脑诱发电位.目的:探讨情感障碍患者与正常成人在关联性负变检测中的不同表现.设计:病例-对照实验.单位:山东省淄博市精神病医院功能科.对象:选择2005-02/2006-01在山东省淄博市第五人民医院就诊和住院的情感障碍患者29例,男14例,女15例,监护人均知情同意,所有患者均符合精神病诊断与分类手册DSM-Ⅳ的躁狂抑郁症诊断标准.将情感障碍患者按入院时的精神状态分为躁狂相和抑郁相2组.躁狂相组11例,Bech-Rataelson躁狂量表评分大于16分.抑郁相组18例,分为单相(目前抑郁以往无躁狂)11例及双相(目前抑郁有过躁狂)7例,汉密顿抑郁量表评分大于24分.选择27例身心健康的医院职工作为对照组,男14例,女13例,年龄21~53岁,平均年龄(32.5±5.9)岁,3组受试者年龄、性别差异无显著性.方法:实验在屏蔽的隔音室中进行,被试者坐于软椅上,双眼向前看一目的物,在实验过程中,保持清醒.记录电极用8 mm铂金头皮电极,位置参照国际脑电图学会10/20标准.颅顶有效电极置于Cz,参考电极置于右乳突.两眉中点上2 cm处接地.关联性负变波形用函数记录仪描记.标准的关联性负变模式由光信号及短声信号组成.闪光灯和扬声器置于被试者正后方,被试者双耳接受短声信号后,即用右手指按手握式电键,瞬时切断短声.从同步光信号发出开始,全程持续2 500 ms为一次关联性负变记录,每20次叠加为一轮实验.每例被试者接受2轮实验,实验结束后,以20μV标准电压输入上述系统作同样次数叠加处理,作为波幅测量标准.主要观察指标:各组受试者的关联性负变的潜伏期、波幅B、指令信号前负相期待波面积、指令信号后负变化面积.结果:纳入患者56例全部进入结果分析.躁狂相组患者关联性负变波幅B较对照组高[(22

  9. 斑点免疫结合法测定卵黄抗体的活性%Dot-immunobinding assay for the activity of egg yolk anibody

    Institute of Scientific and Technical Information of China (English)

    阮光萍; 安梅; 王桂华; 叶蕾; 邓淑芬

    2007-01-01

    背景:哺乳动物产生的抗体和鸡产生的卵黄抗体在物理、生物活性方面存在差异.卵黄抗体能耐酸耐热,可口服用来防治动物和人类的肠内感染疾病,且对发展常规的诊断免疫实验有益.传统的ELISA法检测卵黄抗体比斑点免疫结合法费时.目的:应用斑点免疫结合法检测卵黄抗体的稳定性.设计:开放性实验.单位:解放军成都军区昆明总医院输血科.材料:实验于2006-01/06在解放军成都军区昆明总医院完成.选取30周龄的白色莱杭母鸡2只,以HLA-A*0201α链作为抗原,纯化抗原的总蛋白浓度0.04 g/L,相对分子质量为32 000(自行制备);硝酸纤维素膜(进口分装);脱脂奶粉(安怡产品,批号20051220);DAB(博士德公司);辛酸(上海星火化工厂生产);硫酸铵(汕头市光华化学厂生产).方法:①抗原HLA-A*0201α链以总蛋白浓度0.04 g/L纯化后,进行鸡卵黄抗体的纯化,采用SDS-PAGE电泳检测卵黄抗体的纯化结果.②1μL抗原被点样在硝酸纤维素膜的中心,于37℃孵箱中烤干,浸于1 mL的PBST中,37℃孵箱90 r/min封闭振荡15 min,重新更换1 mL的PBST,加入一抗卵黄抗体,终浓度为10 mg/L.在37℃孵箱振荡30 min后,硝酸纤维素膜用PBST洗3次.加入二抗标记HRP的鼠抗鸡卵黄抗体,孵育30 min后,硝酸纤维素膜用PBST洗3次,通过用DAB试剂孵育来显色.阳性反应产生一个深棕色的斑点,表明卵黄抗体具有较好的活性;斑点变浅表明失去部分活性;斑点消失表明失去全部活性.根据斑点的灰度值变化对照标准样品,可计算卵黄抗体剩余的百分活性.③卵黄抗体用磷酸盐缓冲液调整为1,0.1,0.01 g/L 3种蛋白浓度,室温下放置4个月,每个月分别从各种浓度的样品中取10μg,采用斑点免疫结合法检测卵黄抗体室温稳定性.④卵黄抗体分别置于7个EP管,100 μL/管,编号1~7.1~3号管用1 mol/L的HCL分别调整pH值为5,3,2;4~6号管用1 mol/L

  10. Separation of high-class alkanols and high-class eicosanoic acids in sugar cane wax and activity of reducing blood cholesterol%蔗蜡高级烷酸和高级烷醇分离与降胆固醇的作用

    Institute of Scientific and Technical Information of China (English)

    刘方欣; 张玉诺; 李晓愚; 谢娟; 王敏; 刘先俊

    2007-01-01

    背景:甘蔗蜡作为制糖工业的副产品,在非医药方面已有广泛的用途.有实验证实,甘蔗蜡在降低血胆固醇方面具有良好的作用,但其效应及适用于医药应用的甘蔗蜡的分离手段有待进一步研究.目的:从国产甘蔗蜡中分离适合医药用途的高级烷酸混合物、高级烷醇混合物,并观察其对高脂血症模型大鼠的降胆固醇作用.设计:随机对照动物实验.单位:重庆康尔威药业股份有限公司药物研究所.材料:实验于2005-04/2006-01在重庆康尔威药业股份有限公司药物研究所完成.选用65只成年Wistar雌性大白鼠,体质量180~220 g,鼠龄3,~6个月,SPF级,由重庆中药研究院实验动物中心提供.粗甘蔗蜡购自北京嘉德鸿盛生物化学科技有限公司.26C醇、28C醇、30C醇、32C醇和28C酸、30C酸、32C酸、34C酸为Sigma产品(气相色谱标准品).其余试剂为国产分析纯级.方法:①将粗甘蔗蜡通过乙醇等有机溶剂反复提取后成为精制甘蔗蜡,进一步通过皂化、加钙等,将高级烷酸混合物与高级烷醇混合物分离.用气相色谱分析其主要成分,高级烷醇混合物主要分析C26、C28、C30和C32,高级烷酸混合物主要分析C26、C28、C30和C32.②按照参考文献叙述的方法,将大白鼠适应性饲养3d后,随机摸球法分为空白组(n=10)和实验组(n=55),断尾采血,自动生化分析仪测定所有大鼠三酰甘油、总胆固醇与高密度脂蛋白胆固醇.空白组给予普通颗粒饲料,实验组给予高脂饲料(猪油质量分数0.1、蛋黄粉质量分数0.1、胆固醇质量分数0.01、猪胆盐质量分数0.002、普通饲料质量分数0.788)[3],自由摄食与饮水.7 d后尾尖再次采血测定三酰甘油、总胆固醇与高密度脂蛋白胆固醇.按血清三酰甘油的高低随机将实验组大白鼠分为5个亚组:阴性对照组、高级烷醇低剂量组、高级烷醇高剂量组、高级烷酸低剂量组、