Estudio del streaming de audio y vídeo sobre redes heterogéneas

OpenAIRE

Gómez Cruz, María del Carmen

2009-01-01

Las operadoras han encontrado nichos de negocio en la integración de múltiples servicios avanzados, como pueden ser Voz sobre IP, Vídeos bajo demanda, datos de alta capacidad, distribución de televisión de alta definición, etc. Esto supone una adaptación constante de sus redes de comunicación de banda ancha para soportar mayores anchos de banda, con mayor alcance, con menores pérdidas, en definitiva con mayores prestaciones; y promueve el desarrollo por parte de los fabricantes de audio y víd...

LA VOZ DEL ALUMNADO: SU SILENCIO Y LA CULTURA PROFESIONALISTA

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Paula Escobedo Peiro

2017-01-01

Full Text Available El artículo que presentamos se centra en el estudio realizado en una escuela de Educación Infantil y Primaria. El objetivo de dicho estudio es conocer la voz del alumnado en el centro, y sobre todo entender por qué en una escuela que intenta transformarse para ser más intercultural e inclusiva, la voz del alumna - do queda silenciada. Metodológicamente se trata de un estudio de caso, en el que mediante grupos de discusión, entrevistas y observación participante tra - tamos de comprender las perspectivas de los participantes en profundidad. Los principales resultados apuntan a la cultura profesionalista de los maestros y las maestras, como un aspecto que influye negativamente en la participación de las familias y del alumnado. Además, el hecho de escuchar la voz del alumnado, nos permite tener una visión más completa del centro y conocer algunas de las contradicciones que se dan en la práctica. Como conclusiones, destacamos la importancia de rescatar la voz del alumnado y fomentar su participación activa en el centro, no solo para crear una escuela más participativa y democrática, sino también para obtener una mirada más completa de la institución.

Investigation on possible risks to human health by exposure to the radiation of electromagnetic waves produced by the radio communications; Investigacion sobre posibles riesgos a la salud humana por exposicion a la radiacion de ondas electromagneticas producidas por las radiocomunicaciones

Energy Technology Data Exchange (ETDEWEB)

Garcia Hernandez, Carlos Felipe; Ibarguengoytia Gonzalez, Pablo Hector; Flores Garcia, Andres; Franco Campos, Laura Elena [Instituto de Investigaciones Electricas, Cuernavaca, Morelos (Mexico)

2011-06-13

This verification procedure is based on a research work on the possible risks to human health by exposure to the radiation of electromagnetic waves produced by the radio communications, cases of study: cellular telephony, radio digital troncalized and wireless telephony IP of Voice on IP (wireless local area network). The revision of all the international standards and the applicable national standardization was included, as well as the verification of fulfillment. [Spanish] Este procedimiento de verificacion esta basado en un trabajo de investigacion sobre posibles riesgos a la salud humana por exposicion a la radiacion de ondas electromagneticas producidas por la radiocomunicaciones, casos de estudio: telefonia celular, radio troncalizado digital y telefonia IP inalambrica de Voz sobre IP (red de area local inalambrica). Se incluyo la revision de todos los estandares internacionales y de la normatividad nacional aplicable, asi como la verificacion de cumplimiento.

La mujer en "La Voz del Interior" representaciones de género de 1973-1983 The Woman in "La Voz del Interior" Gender Representations 1973-1983

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Marta Palacio

2011-12-01

Full Text Available Este ensayo presenta un análisis discursivo de las representaciones de género sobre la mujer contenidas en La Voz del Interior, periódico de la Ciudad de Córdoba, en algunos ejemplares publicados durante dos períodos socio-políticos cotejados: el breve período democrático de 1973-1976 y el período de la dictadura militar de 1976-1983.This paper presents a discursive analysis of gender representations on women in La Voz del Interior, the newspaper of the city of Córdoba, in some issues published during two socio-political compared periods, the brief democratic period 1973-1976 and the period of the military dictatorship of 1976-1983.

Health disorders and teachers' voices: a workers' health issue Alteraciones de la salud y de la voz del profesor, un asunto de salud del trabajador Alterações da saúde e a voz do professor, uma questão de saúde do trabalhador

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Liliana Amorim Alves

2009-08-01

Full Text Available Environmental and/or work risk factors, lack of basic knowledge related to voice, its incorrect use, and a defective vocal model can lead teachers to develop occupational dysphonia. This study aimed to analyze studies focusing on occupational vocal disorders through a literature review. Articles published over a period of 11 years in periodicals indexed in the ScieLO library were searched according to predetermined inclusion and exclusion criteria. Twenty articles related to teachers' vocal occupational disorders were found. We argue that intense vocal use should not harm professionals; the voice has to be pleasant to the speaker and correctly produced. The conclusion is that there is a scarcity of articles available at the studied library relating to teachers' voice disorders. Further studies need to be developed and disseminated so as to increase knowledge in the subject.Factores de riesgos ambientales y/o referentes a la organización laboral, ausencia de nociones básicas sobre la voz, su uso incorrecto y presencia de modelo vocal deficiente pueden llevar al profesor a presentar disfonía relacionada al trabajo. El objetivo de este estudio fue analizar publicaciones sobre alteraciones vocales provenientes del trabajo, a través de revisión de literatura sobre el tema propuesto. Como método, se buscó artículos de periódicos indexados en la biblioteca virtual Scielo, por un período de once años, obedeciendo a criterios de inclusión y exclusión predeterminados. Fueron encontrados 20 artículos que contemplaron alteraciones vocales de los profesores provenientes del trabajo. Se discute, aquí, que el uso vocal intenso no debe propiciar perjuicios a la profesión; la voz debe ser agradable al sujeto y producida correctamente; concluyéndose que hay pocos artículos vehiculados en la biblioteca investigada relacionados a las alteraciones vocales del profesor, provenientes del uso de la voz en el trabajo. Nuevas investigaciones deben ser

Comparação dos tempos de geração e digitação de laudos radiológicos entre um sistema eletrônico baseado em voz sobre IP (VoIP e um sistema tradicional baseado em papel Comparison between the time required to generate and type radiology reports by means of VoIP-based system and a traditional paper-based system

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Dácio Miranda Ferreira

2010-02-01

Full Text Available OBJETIVO: Comparar os tempos de geração e digitação de laudos radiológicos entre um sistema eletrônico baseado na tecnologia de voz sobre o protocolo de internet (VoIP e o sistema tradicional, em que o radiologista escreve o laudo à mão. MATERIAIS E MÉTODOS: Foi necessário modelar, construir e implantar o sistema eletrônico proposto, capaz de gravar o laudo em formato de áudio digital, e compará-lo com o tradicional já existente. Por meio de formulários, radiologistas e digitadores anotaram os tempos de geração e digitação dos laudos nos dois sistemas. RESULTADOS: Comparadas as médias dos tempos entre os sistemas, o eletrônico apresentou redução de 20% (p = 0,0410 do tempo médio de geração do laudo em comparação com o sistema tradicional. O tradicional foi mais eficiente em relação ao tempo de digitação, uma vez que a média de tempo do eletrônico foi três vezes maior (p OBJECTIVE: To compare the time required for generation and typing of radiology reports by means of an electronic system based on the technology of voice over internet protocol (VoIP and the traditional system, in which the report is handwritten by the radiologist. MATERIALS AND METHODS: It was necessary to model, build and deploy the proposed electronic system, capable of recording the reports in a digital audio format and comparing it with the traditional method. Radiologists and transcriptionists recorded the reports generation and typing times for both systems, using appropriate forms. RESULTS: When the mean times between both systems were compared, those from the electronic system presented a reduction of 20% (p = 0.0410 in the report generation time as compared with the traditional method. On the other hand, the traditional method was more efficient with respect to typing time, as the mean typing time with the electronic system was three times longer (p < 0.0001. CONCLUSION: The results demonstrated a statistically significant difference

Redes convergentes

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Ángela Marcela Mejía Fajardo

2004-01-01

Full Text Available Las redes convergentes o redes de multiservicio hacen referencia a la integración de los servicios de voz, datos y video sobre una sola red basada en IP como protocolo de nivel de red. En este artículo se presenta la integración de servicios de voz sobre redes IP (VoIP como ejemplo de red convergente. La arquitectura de esta red está constituida básicamente, por el media gateway, el controlador de media gateway, el gateway de señalización y el gatekeeper. Las redes de convergencia han tenido y tendrán aún dificultades técnicas qué superar ya que los distintos servicios por ofrecer tienen diferentes características y requerimientos de red, por tanto es importante hablar aquí de ingeniería de tráfico y mecanismos que garanticen calidades de servicio.

Human rights treatment in La Voz de Galicia/Tratamiento de derechos humanos en La Voz de Galicia

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Dra. Mercedes Román Portas

2009-01-01

Full Text Available Abstract: This article summarizes the results of an investigation pertaining to “Human Rights and the Written Press.” The project resulted from a collaborative effort between teachers from the Universidad Complutense de Madrid and the Universidad de Vigo in response to an accord established by the Fundacion Ciudadania y Valores. The general goal of this project is to employ quantitative content analysis methods to analyze the types of human rights-related press information received by readers of the regional newspaper, La Voz de Galicia. The specific objective of the research project was to study the level of interest that exists among readers regarding human rights reporting in La Voz de Galicia. The investigators demonstrate the quantitative frequency of contents reported in this newspaper related to human rights by presenting the analytical results of topics grouped by four select articles pertaining to the Universal Human Rights Declaration.Resumen: Este trabajo es fruto de un proyecto más amplio de investigación ya finalizado. La Fundación Ciudadanía y Valores estableció un acuerdo con un equipo de investigación integrado por profesores de la Universidad Complutense de Madrid y la Universidad de Vigo para realizar un primer informe sobre “Derechos Humanos y prensa escrita”. El objetivo global de este artículo consiste en analizar, mediante análisis de contenidos cuantitativos, el discurso mediático que los lectores del diario regional La Voz de Galicia, recibe de este periódico en relación con determinados aspectos de los derechos humanos. Los objetivos específicos de la investigación se centraron en estudiar el grado de interés que existe por los derechos humanos en este diario regional. Es decir, el grado de presencia de contenidos vinculados a este concepto. Al final del texto se presentan los resultados del análisis de los tópicos agrupados por los cuatro artículos de la Declaración Universal de Derechos

LA VOZ EN EL DISCURSO ACADÉMICO

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Nicolás Polo Figueroa

2012-06-01

Full Text Available En aras del positivismo imperante en las aulas académicas, el término voz estaba proscrito del discurso académico. El escritor solo podía hablar en la forma impersonal se; la voz del colectivo científico al que le prestaba la voz. Gracias a renovados vientos en las ciencias humanas, la intersubjetividad en el discurso académico ha salido del clóset; los académicos están dejando oír su propia voz, aunque son muy conscientes de que tras esta hay una sinfonía de voces: la colectiva, la intersubjetiva, la social y la discursiva. Una mirada a estas es el objeto de esta comunicación.

PROPUESTA INICIAL PARA EL DESARROLLO DE UNA METODOLOGÍA PARA LA IMPLEMENTACIÓN DE IPTv6 SOBRE IMS

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Jean Paul Granados Cárdenas

2013-09-01

Full Text Available La televisión digital ha evolucionado continuamente desde su presentación digital terrestre (DVB-T, pasando por el estándar satelital (DVB-S hasta llegar a su presentación actual conocida como IPTV (Internet Protocolo Television que ofrece múltiples servicios multimedia tales como voz, video y datos, transportados con ciertos niveles de calidad de servicio, seguridad, interactividad y confianza gracias a la utilización de la pila de protocolos TCP/IP. En tal sentido el artículo pone a disposición de la comunidad académica una propuesta  metodológica inicial que pretende servir de guía en la implementación de este tipo de sistemas sobre una plataforma de libre distribución conocida como IMS (IP Multimedia Subsystem para redes de área local tipo IPv6.

Estudio comparativo de los Códecs de voz para comunicaciones de Voip utilizando teléfonos inteligentes - caso de estudio Universidad Católica de Cuenca sede Azogues

OpenAIRE

Ortega Ortega, Martín Educardo

2015-01-01

Este trabajo de investigación presenta un estudio comparativo de los códecs de voz para comunicaciones de VoIP en la Universidad Católica de Cuenca Sede Azogues, mediante la aplicación de diferentes escenarios reales de pruebas utilizando teléfonos móviles celulares inteligentes con cuentas SIP registradas en aplicaciones softphones y configuradas con la dirección IP interna del servidor de VoIP cuando la conexión sea a través de la red WLAN interna del campus universitario,...

Voz cantada e a constituição da relação mãe-bebê

OpenAIRE

Mello,Enio Lopes; Maia,Suzana Magalhães; Andrada e Silva,Marta Assumpção de

2009-01-01

TEMA: refletir sobre uma faceta da constituição da relação mãe-bebê, que se fez presente no uso criativo da voz cantada da mãe, na comunicação com o seu bebê. PROCEDIMENTOS: o único sujeito desse estudo é uma mãe, que se submeteu a oito sessões de terapias corporais associadas à emissão da voz cantada, sempre dirigidas ao bebê; as sessões transcorreram com a possibilidade de expressão livre pela fala e gesto da mãe e a escuta do terapeuta. RESULTADOS: o quadro que a mãe apresentava em relação...

Distúrbio de voz e trabalho docente

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Léslie Piccolotto Ferreira

Full Text Available RESUMO Objetivo: analisar a associação entre distúrbio de voz e capacidade para o trabalho em docentes da rede municipal de ensino de São Paulo. Métodos: professoras que buscaram atendimento fonoaudiológico, com queixa de alteração vocal; e professoras selecionadas sem queixa, expostas ao mesmo ambiente de trabalho, passaram por avaliação perceptivo-auditiva da voz; preenchimento dos protocolos Índice de Capacidade para o trabalho e Condição de Produção Vocal do Professor; e avaliação perceptivo-visual da laringe. Foram classificadas como Caso as que tinham alteração na avaliação perceptivo-auditiva e em pregas vocais (167 e Controle as sem alterações nas avaliações (105. Resultados: a capacidade para o trabalho esteve entre baixa e moderada entre os casos (67,4% e entre boa e ótima (66,6% nas professoras do controle (escore total. Houve associação estatística em duas dimensões do ICT, apontando que as docentes com distúrbio de voz apresentaram quase três vezes mais chance de perder capacidade para o trabalho e que quanto pior a perda da capacidade, mais forte é a associação com o distúrbio de voz. Conclusão: há associação entre o distúrbio de voz e as dimensões capacidade atual para o trabalho comparada com a melhor de toda vida, indicando que os sujeitos que apresentaram distúrbio de voz estavam em sua pior capacidade para trabalhar, e perda estimada para o trabalho por causa de doenças, indicando que quanto maior a perda da capacidade para o trabalho, mais forte é a relação com o distúrbio de voz, independente da idade.

LA VOZ ARTICULADA O PALABRA EN LA TRANSMISIÓN Y ADQUISICIÓN DE CONOCIMIENTOS

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Dahirys Mora Mora

2014-03-01

Full Text Available El éxito de la clase depende de que los estudiantes entiendan y obedezcan las órdenes y explicaciones del profesor, pues mediante su voz articulada o palabra él organiza y dirige la transmisión y adquisición de conocimientos, el desarrollo de habilidades y destrezas, así como sentimientos, convicciones y particularidades de la voluntad y el carácter. Para este propósito el mismo debe poseer una amplia cultura sobre la voz humana, sus características, funcionamiento y las potencialidades con que cuenta su aparato de fonación para hacer un uso adecuado y óptimo durante la dirección del proceso de enseñanza aprendizaje. El presente trabajo está destinado a los docentes en formación de las carreras pedagógicas, en especial a los de Español-Literatura, que deben distinguirse por ser un modelo lingüístico.

Representar la muerte : Un análisis de las técnicas narrativas en La voz dormida, de Dulce Chacón

OpenAIRE

Vidhall, Martin

2015-01-01

El propósito de esta tesina es ampliar los conocimientos sobre la narrativa de Dulce Chacón al analizar cómo la aplicación de técnicas narrativas en La voz dormida refuerza la impresión trágica y triste de la muerte de Hortensia, una de las protagonistas de la novela. Para llevar a cabo el objetivo se ha identificado las técnicas narrativas más frecuentes e importantes para la presentación de los sucesos relacionados con la trama de Hortensia. El análisis demuestra que La voz dormida tiene un...

Sistema de navegación automática controlada por voz para una silla de ruedas

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Marcelo Arévalo Luzuriaga

2010-12-01

Full Text Available Español:El objetivo principal del presente proyecto fue desarrollar un sistema autónomo capaz de movilizar a personas discapacitadas parapléjicas sobre una silla de ruedas, utilizando un simple comando o instrucción de voz.El sistema de control del navegador está basado en un microcontrolador tipo PIC 16f877A como elemento maestro del comando y de 2 microcontroladores esclavos para la ejecución del reconocimiento de voz y manejo de los actuadores. El microcontrolador RCS 300 realiza el almacenamiento y reconocimiento de los comandos de voz utilizados para el control del equipo.Este equipo posee también la alternativa de un comando manual mediante un joystick ubicado en la parte frontal de la silla, siendo esta función una de las 15 posibilidades de trabajo que posee el equipo, así mismo el sistema está dotado con un conjunto de 6 sensores ultrasónicos programables que entran a funcionar en el modo autónomo y sirven de seguridad al hablante ante posibles colisiones con obstáculos en todo su perímetro y también abismos que encuentre durante su trayectoria.

Distúrbio de voz em professores: autorreferência, avaliação perceptiva da voz e das pregas vocais Voice disorders in teachers: self-report, auditory-perceptive assessment of voice and vocal fold assessment

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Maria Fabiana Bonfim de Lima-Silva

2012-12-01

Full Text Available OBJETIVO: Analisar a presença do distúrbio de voz em professores na concordância entre autorreferência, avaliação perceptiva da voz e das pregas vocais. MÉTODOS: Deste estudo transversal, participaram 60 professores de duas escolas públicas de ensino fundamental e médio. Após responderem questionário de autopercepção (Condição de Produção Vocal do Professor - CPV-P para caracterização da amostra e levantamento de dados sobre autorreferência ao distúrbio de voz, foram submetidos à coleta de amostra de fala e exame nasofibrolaringoscópico. Para classificar as vozes, três juízes fonoaudiólogos utilizaram à escala GRBASI e, para pregas vocais (PPVV, um otorrinolaringologista descreveu as alterações encontradas. Os dados foram analisados descritivamente, e a seguir submetidos a testes de associação. RESULTADOS: No questionário, 63,3% dos participantes referiram ter ou ter tido distúrbio de voz. Do total, 43,3% foram diagnosticados com alteração em voz e 46,7%, em prega vocal. Não houve associação entre autorreferência e avaliação da voz, nem entre autorreferência e avaliação de PPVV, com registro de concordância baixa entre as três avaliações. Porém, houve associação entre a avaliação da voz e de PPVV, com concordância intermediária entre elas. CONCLUSÃO: Há maior autorreferência a distúrbio de voz do que o constatado pela avaliação perceptiva da voz e das pregas vocais. A concordância intermediária entre as duas avaliações prediz a necessidade da realização de pelo menos uma delas por ocasião da triagem em professores.PURPOSE: To analyze the presence of voice disorders in teachers in agreement between self-report, auditory-perceptive assessment of voice quality and vocal fold assessment. METHODS: The subjects of this cross-sectional study were 60 public elementary, middle and high-school teachers. After answering a self-awareness questionnaire (Voice Production Conditions of

La insustancia de la voz

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Isabelle Morin

2009-07-01

Full Text Available La voz es el punto primitivo deinserción del deseo del Otro. Apartir de este dato fundamentalIsabelle Morin intenta respondera la pregunta planteada por Lacanrespecto a lo que ocurre con la pulsiónal final del análisis. La autorapropone que, al final del análisis, elanalizante se encuentra, así sea porun momento, con una extraccióndel a minúscula del objeto, su sustanciagozante para dejar el objetovoz al desnudo. Esta insustancia delobjeto es interrogada a partir detestimonios de los músicos GlennGould y Pascal Dusapin, quieneshan buscado extraer el sonido de lamúsica para reducirla a la letra.Palabras clave: voz, sonido, insustancia,extracción de goce, objeto a.

Telefonía IP (ToIP): principios fundamentales, arquitectura y aspecto regulatorio en el Ecuador

OpenAIRE

Narváez García, William Fernando; Ugalde Peña, Pablo Esteban

2006-01-01

En este documento, hemos tratado de explicar el funcionamiento de la telefonía IP dentro de poco, comenzamos hablando con una introducción al tema al comentar sobre la actual tendencia a la conocida como patrón ALL-IP. Luego hemos visto conveniente hacer un comentario acerca de la evolución de las telecomunicaciones desde sus primeros pasos con Guillermo Marconi hasta nuestros días con la ToIP. De modo que existe un concepto claro de lo que la ToIP significa, en primer lugar se explica ...

¿Crees que tu voz es única?

OpenAIRE

Cerdà Massó, Ramon

2011-01-01

Desde el punto de vista forense —o, más exactamente, criminalístico—, la unicidad de la voz no se puede dilucidar como la experiencia cotidiana, de manera intuitiva. Lo ideal sería establecer qué rasgos digitalmente identificados conforman la voz de cada uno, incluso por encima de alteraciones voluntarias o inconscientes debidas a cambios ambientales o a trastornos biológicos. Mientras esto se ha conseguido desde hace años por lo que respecta a rasgos generales, necesarios para la identificac...

Desarrollo de la competencia prosódica en la lectura en voz alta: importancia de las pausas

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Aintzane Etxebarria

2016-01-01

Full Text Available En los últimos años se ha constatado un aumento de estudios sobre los elemen - tos prosódicos del texto (tono, pausas, etc., que defienden la necesidad de trabajar estos componentes de la competencia comuni - cativa oral para mejorar la comprensión de los textos leídos en voz alta. Con el objetivo de estudiar las pausas como elementos que estructuran el discurso, en este estudio se computan los tipos de pausas, se identifican algunos aspectos a trabajar y, por último, se especifica el peso de algunas variables como las lenguas maternas, el género y la proce - dencia en la realización de las pausas den - tro de estructuras indivisibles. Para ello se ha realizado un experimento a partir de un texto periodístico, leído en voz alta, sobre un corpus de 100 informantes vascos bilingües con edades comprendidas entre los 18 y 25 años, y estudiantes de las Escuelas de Ma - gisterio de la UPV/EHU. Del estudio estadís - tico de los datos se concluye que los tipos de pausas más empleados por los jóvenes lecto - res son las silenciosas, que la posición de las pausas a menudo es incorrecta y que las len - guas maternas influyen significativamente en este hecho.

La voz del amauta en el poema Llamado a algunos doctores (Huk Doctorkunaman Qayay

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Rolando Álvarez

2011-07-01

Full Text Available En este trabajo, se pretende establecer, algunas relaciones que el poema de José María Arguedas, Llamado a algunos doctores, construye con determinados rasgos del pensamiento mostrado por el autor en Todas las sangres, Los ríos profundos, Warma Kuyay y El zorro de arriba y el zorro de abajo; así como en la mesa redonda sobre Todas las sangres de junio de 1965. Se intenta encontrar, en la voz poética, la voz del amauta, en la forma en que el poeta expresa su relación con la naturaleza y con lo divino. This paper seeks to establish some relationships that the poem of Jose Maria Arguedas, Llamado a algunos doctores, established with certain features of the thought expressed by the author in Todas las sangres, Los ríos profundos, Warma Kuyay and El zorro de arriba y el zorro de abajo; as well the roundtable of june of 1965 about Todas las sangres. It tries to find the poetic voice in the voice of amauta in the way the poet expresses his relationship with nature and the divine.

Violência e apagamento da voz indígena no Brasil - O caso Yanomami

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Priscila Maria de Barros Borges

2016-03-01

Full Text Available O presente texto apresenta discussão sobre a lacuna na História Oficial brasileira que corresponde à voz indígena, ainda hoje silenciada. Pretende demonstrar que este silenciamento foi/é construído através de violências de várias ordens ao longo da constituição de nossa historiografia. Na atualidade as diversas minorias têm promovido um movimento de contar sua própria versão da História, através da publicação de livros e produção de documentários. Entre os povos indígenas não é diferente, exemplo disso é o livro A queda do céu, assinado pelo xamã e líder yanomami Davi Kopenawa em parceria com o antropólogo Bruce Albert. A obra A queda do céu, é aqui brevemente interpretada à luz dos conceitos de memória e testemunho, dando destaque à necessidade de que a voz indígena seja disseminada e ouvida, principalmente entre a sociedade não-indígena.

SOBRE A INTERFERÊNCIA NECESSÁRIA DA VOZ NA LEI : O EXEMPLO DA TRAGÉDIA ANTIGA

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Jean-Michel Vivès

2013-02-01

Full Text Available Nessa conferência, proferida especialmente pelo autor a convite da Comissão Científica do Colóquio Internacional « A Psicanálise e a Lei »  é abordada a estrutura da tragédia antiga retomada a partir do entendimento que dela faz Claudel, na medida em que destaca a sua dimensão essencialmente vocal. Partindo da definição dada, pelo citado poeta, da tragédia como um  « long cri devant une tombe mal fermée », o autor procura dela tirar todas as consequências para pensar as questões referentes à voz e a lei naquilo que diz respeito à clinica psicanalítica. Leva ainda em consideração as contribuições de Nietzsche, acerca do nascimento da tragédia, e de Loraux que também chama a atenção para a dimensão vocal da tragédia, pondo em Nessa conferência, proferida especialmente pelo autor a convite da Comissão Científica do Colóquio Internacional « A Psicanálise e a Lei »  é abordada a estrutura da tragédia antiga retomada a partir do entendimento que dela faz Claudel, na medida em que destaca a sua dimensão essencialmente vocal. Partindo da definição dada, pelo citado poeta, da tragédia como um  « long cri devant une tombe mal fermée », o autor procura dela tirar todas as consequências para pensar as questões referentes à voz e a lei naquilo que diz respeito à clinica psicanalítica. Leva ainda em consideração as contribuições de Nietzsche, acerca do nascimento da tragédia, e de Loraux que também chama a atenção para a dimensão vocal da tragédia, pondo em evidencia sua dimensão política. O tratamento dessas questões levam o autor a formular a hipótese: a instauração e a relação à lei, que é uma das questões essenciais apresentadas pela tragédia, não poderia ser pensada ao redor de sua relação à voz ?

La periferia: voz y sentido en los estudios urbanos

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Daniel Hiernaux

2004-01-01

Full Text Available En este trabajo exploramos la voz ‘periferia’ el contexto latinoamericano: cómo cambia tiempo que el fenómeno denotado se transforma y cómo agrega nuevos componentes en el diálogo entre la palabra y el fenómeno. Por ser una voz reciente, también revisamos otras voces emparentadas (‘arrabal’ y ‘suburbio’, reconstruyendo el uso y sentido cada una de ellas y la sustitución de unas otras hasta que aparece la palabra ‘periferia’. La expansión de las metrópolis y la constitución de amplios espacios periféricos sido de mucho interés en los estudios urbanos. No obstante, hay numerosos aspectos poco analizados. En el primer apartado revisamos voces antecedentes. Luego reconstruimos contexto en el que se comienza a referir territorio de expansión de la ciudad con palabra ‘periferia’, así como sus implicaciones en cuanto al sentido de la voz. En el apartado siguiente analizamos las dimensiones que incorporó la voz ‘periferia’ en relación procesos urbanos; para terminar con los desafíos actuales en torno a ese territorio las formas de nombrarlo

Perda da voz em professores e não professores Voice loss in teachers and non-teachers

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Kelly Park

2009-01-01

Full Text Available OBJETIVO: Verificar a percepção de professores e não-professores sobre as implicações de uma eventual perda de voz. MÉTODOS: Participaram 205 indivíduos sendo 105 professores e 100 não professores entre 23 a 65 anos, 106 mulheres e 99 homens. Foi aplicado um questionário contendo quatro perguntas referentes a uma eventual perda de visão, audição, voz e deambulação e o grau de impacto inferido (de 0 a 4. RESULTADOS: Para o grupo de professores, não enxergar gerou o maior impacto negativo (média de 3,8, seguido por não andar (média de 3,7, não ter voz (média de 3,7 e não ouvir (média de 3,6. Para o grupo de não-professores, não enxergar também gerou o maior impacto negativo (média de 3,4, seguido por não andar (média de 3,0; não ouvir (média de 2,2 e não ter voz (média de 2,0. Em relação ao maior impacto de uma eventual perda da voz, professores indicaram prejuízos no trabalho, relacionamento social e atividades rotineiras e, no grupo de não professores, nas atividades rotineiras, trabalho, relacionamento social e manifestações das emoções. CONCLUSÕES: Os professores valorizam sua voz de modo diverso dos não-professores e ambos os grupos avaliam a perda da voz como algo que não acarreta consequências negativas. Apesar de o professor perceber mais o impacto de um eventual problema de voz do que o não-professor, os sentimentos em relação à perda da voz foram muito semelhantes nos dois grupos.PURPOSE: To investigate teachers' and non-teachers' perception regarding the implications of an eventual loss of voice. METHODS: Participated in the study 205 individuals (106 women and 99 men, 105 teachers and 100 non-teachers, with ages varying from 23 to 65 years old. The participants were asked to answer a questionnaire with four questions regarding an eventual loss of vision, hearing, voice and deambulation, and the inferred impact degree (from 0 to 4. RESULTS: For the teachers group, not being able to see

Reseña de Carrasco Bengoa (Ed.) (2014). Con voz propia. La economía feminista como apuesta teórica y política

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Medina-Vicent, Maria

2015-01-01

Con voz propia. La economía feminista como apuesta teórica y política, es una obra coordinada por Cristina Carrasco y compuesta de nueve capítulos, donde diferentes autoras aportan su visión sobre la teoría económica feminista, subrayando su potencial crítico para cuestionar patriarcado y capitalismo 

Os sentidos atribuídos à voz por mulheres após a menopausa The meanings attributed to the voice by menopause women

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Maria Aparecida Miranda de Paula Machado

2005-04-01

Full Text Available OBJETIVO: Analisar os sentidos atribuídos à voz por mulheres após a menopausa. MÉTODOS: Foram coletados dados de 148 mulheres nos prontuários médicos, entre fevereiro de 2000 e outubro de 2001, no Programa da Saúde da Mulher no Climatério, do ambulatório de ginecologia de um hospital na cidade de Curitiba, Estado do Paraná. Dentre a população total foram selecionadas intencionalmente 30 mulheres entre 48 e 59 anos, que não se consideravam profissionais da voz, no mínimo há 12 meses em amenorréia, e que foram entrevistadas com um roteiro temático, constituído de questões semi-estruturadas. Cada entrevista foi gravada e transcrita. A descrição, análise e interpretação foram fundamentadas pelas representações sociais, por meio do discurso do sujeito coletivo, com aproximações à hermenêutica-dialética. RESULTADOS: Os 27 discursos coletivos estruturados denotaram o relacionamento da voz às características biológicas, psicológicas e aspectos sociais do cotidiano, com a identificação de mudanças vocais no decorrer da vida. CONCLUSÕES: Foi possível observar representações sociais de natureza comunicacional e funcional, que salientaram a voz como elemento de constituição da identidade pessoal, concebida na pertinência social. A pesquisa sugere novas investigações fundamentadas nas ciências sociais, simultâneas aos estudos epidemiológicos, e a necessidade de se refletir sobre o processo de terapêutica vocal aplicado sobre uma laringe mais vulnerável, além de priorizar uma proposta de assistência integral à mulher no climatério, com enfoque sobre a saúde da voz.OBJECTIVE: To analyze the meanings attributed to the voice by menopausal women. METHODS: Data were collected from 148 medical records of women seen in the Climacteric Women Health Program of the Irmandade Santa Casa de Misericórdia Gynecology Outpatient Clinic in Curitiba, Brazil, between February 2000 and October 2001. Of them, 30 women aged

Estudio de verificación biométrica de voz

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Aguirrezabala Agustín, Marta

2015-01-01

En este proyecto estudia la posibilidad de realizar una verificación de locutor por medio de la biometría de voz. En primer lugar se obtendrán las características principales de la voz, que serían los coeficientes MFCC, partiendo de una base de datos de diferentes locutores con 10 muestras por cada locutor. Con estos resultados se procederá a la creación de los clasificadores con los que luego testearemos y haremos la verificación. Como resultado final obtendremos un sistema capaz de...

Voz e qualidade de vida de pacientes tratados de câncer avançado de laringe

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Vaneli de Cassia Colombo Rossi

2013-01-01

Resumo: OBJETIVO: Avaliar qualidade de vida e voz de pacientes tratados de câncer avançado de laringe por laringectomia total ou quimioradioterapia exclusiva com preservação de órgão. MATERIAL E MÉTODOS: 30 pacientes tratados de câncer avançado de laringe livres da doença há pelo menos quatro anos: dez laringectomizados totais sem produção de voz esofágica (SVE); dez laringectomizados totais com voz traqueoesofágica (VTE) e dez com voz laríngea. A qualidade de vida foi mensurada pelos protoco...

Voz y blasón del cuerpo femenino

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Rafael Humberto Moreno Durán

1992-05-01

Full Text Available Gracias a la eufonía descubrí el placer y así, gozosamente, arrastrado, por un acento cálido y perturbador, me sumergí en los dominios de la concupiscencia. Y es tal vez esto lo que explica por qué la voz -sólo una forma particular, profunda, tórrida- se ha convertido en mi estímulo más entrañable y recurrente. Porque decir voz es tanto como decir oralidad. Y oralidad no sólo es expresión sino también cópula, pues el lenguaje mismo tiene su origen en el ámbito de lo sexual. ¿Acaso el verbo no se hizo carne? ¿Acaso semántica no viene de semen? Hablar es engendrar.

Qualidade de vida relacionada à voz de professores: uma revisão sistemática exploratória da literatura

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Tânia Maestrelli Ribas

2014-03-01

Full Text Available O objetivo deste estudo foi verificar, por meio de uma revisão sistemática de literatura, os estudos existentes sobre qualidade de vida relacionada à voz de professores. Foram selecionados artigos, nas seguintes bases de dados: Education Resources Information Center ( ERIC, LILACS, PUBMED Central (PMC e SCIELO. Foram empregados os unitermos ‘qualidade de vida’ e ‘voz’ e seus correspondentes na língua inglesa. Foram aceitos artigos em inglês, português ou espanhol, sem determinação quanto ao período de publicação. Para a seleção dos artigos foram previamente estabelecidos critérios de inclusão e exclusão e aplicados os Testes de Relevância I e II. Os artigos foram incluídos de acordo com formulários padronizados. A busca inicial resultou em 315 artigos. O processo de análise envolveu leitura de títulos, resumos e textos completos; sendo que apenas 13 artigos preencheram os critérios de inclusão, envolvendo estudos de qualidade de vida relacionada à voz de professores dos diversos níveis de ensino (infantil, fundamental, médio e superior e de escolas públicas e privadas. O QVV foi o instrumento mais utilizado com professores; sendo o domínio físico deste instrumento o que impactou de forma mais negativa na qualidade de vida relacionada à voz no que se refere a falar forte em ambientes ruidosos e o ar acabar rápido e precisar respirar muitas vezes enquanto fala. Houve certa dificuldade no momento das análises dos artigos, uma vez que não apresentaram padronização de técnicas e critérios semelhantes. Há necessidade de aumento dos estudos de qualidade de vida relacionada à voz do professor nos diferentes níveis de ensino e tipos de escolas.

Qualidade de vida em voz na doença pulmonar crônica

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Bruna Franciele da Trindade Gonçalves

2015-12-01

Full Text Available RESUMO: Objetivo: analisar a qualidade de vida relacionada à voz autorreferida por indivíduos com doença pulmonar crônica. Métodos: estudo transversal, exploratório, quantitativo, com informações obtidas a partir da aplicação de questionário de qualidade de vida em voz em usuários de um ambulatório de fisioterapia integrado em hospital universitário no interior do Rio Grande do Sul, no período de março a novembro de 2012. Resultados: participaram 19 sujeitos, 12 (63,20% do sexo masculino e 7 (36,80% do sexo feminino. Sobre a faixa etária, 14 (73,70% eram adultos e cinco (26,30% idosos, sendo essa diferença estatisticamente significante. Quanto à doença pulmonar crônica, dez (52,60% tinham bronquiectasia, seis (31,60% doença pulmonar obstrutiva crônica e três (15,80% asma. A média do questionário Qualidade de Vida em Voz Total foi de 85,8 ± 5,8 pontos. Não houve diferença estatística entre os três domínios do questionário e as variáveis sexo, idade e diagnóstico médico. Conclusão: predomínio percentual do sexo masculino e faixa etária adulta-meia idade, sendo essa última estatisticamente significante e diagnóstico médico de bronquiectasia. A média do questionário total foi de 85,8 ± 5,8 pontos. Não foram encontradas significância estatística na comparação do domínios do questionário com as variáveis sexo, idade e doença pulmonar. Tal fato pode ser explicado pela elaboração de estratégias de comunicação como forma de minimizar os efeitos da doença pulmonar na produção vocal. Sugere-se a realização de outras pesquisas abordando o mesmo tema, porém com amostras maiores a fim de verificar a significância estatística das variáveis estudadas.

Condicionamento vocal individualizado para profissionais da voz cantada - relato de casos

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Mara Behlau

2014-10-01

Full Text Available Este estudo tem como tema o desenvolvimento de programas de condicionamento vocal individualizado para a demanda específica de três profissionais da voz cantada. Trata-se de um relato de caso de três profissionais da voz cantada: uma cantora e atriz de teatro musical brasileiro, um cantor sertanejo e um cantor de roque. Os três indivíduos foram submetidos à avaliação fonoaudiológica, apresentando queixas relacionadas a cansaço e fadiga após uso da voz e/ou aperfeiçoamento vocal e realizaram avaliação otorrinolaringológica prévia. Os três pacientes estavam em processo de terapia fonoaudiológica, sendo uma das etapas o desenvolvimento de um programa de condicionamento vocal individualizado, de acordo com a demanda, necessidade e disponibilidade de cada sujeito. A cantora e atriz de teatro musical brasileiro aderiu facilmente à proposta personalizada de condicionamento vocal, pois sentia os ganhos de realização uma mobilização fisiológica antes de passar para a técnica-artística que já executava. O cantor sertanejo aderiu facilmente ao programa de condicionamento vocal individualizado, sem nenhuma dificuldade, e relatou extrema melhora em seu conforto e desempenho vocal durante o canto com os exercícios selecionados. O cantor de roque apresentou maior flexibilização de trato vocal, estabilidade da emissão no canto, ampliação da tessitura vocal, maior precisão articulatória e redução da constrição global excessiva após dar início ao programa de condicionamento vocal individualizado.O condicionamento vocal individualizado mostra efeitos positivos, principalmente para os profissionais da voz, pois os indivíduos trabalham exatamente sob a demanda que será utilizada com o uso profissional da voz,com exercícios específicos e direcionados para suas necessidades.

“Sou feito de palavras”: A(s voz(es narrativa(s em O Inominável de Samuel Beckett

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Lucianno Gatti

2016-02-01

Full Text Available O artigo discute a questão da voz narrativa no romance O inominável de Samuel Beckett. Com base em estudos genéticos da composição do romance, discute-se a função literária de temas como a crítica à linguagem e à consciência, assim como suas consequências para se pensar o gênero do romance. O artigo retoma então uma discussão sobre realismo em textos de Adorno e Lukács com o intuito de debater a centralidade da fábula, sua estrutura temporal e a relação da forma com a experiência histórica. Por fim, tentaremos retomar essas questões a partir da análise de um momento específico do romance de Beckett. Com isso, as questões teóricas anteriormente expostas deverão ganhar concretude no esforço de elucidar problemas da composição do romance, como o feitio episódico do conjunto, a identidade da voz narrativa, a especificidade do monólogo interior e a confluência entre narrativa e reflexão.

Estudio de la tecnología VoIP a través de Elastix

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Perera Domínguez, José Álvaro

2013-01-01

Estudio sobre cómo encaja la tecnología IP en el mundo de la telefonía para ver qué ventajas e inconvenientes supone cada posible solución a un problema, y elegir la mejor. Estudi sobre l'encaix de la tecnologia IP en el món de la telefonia per veure quins avantatges i inconvenients suposa cada possible solució a un problema, i triar la millor.

Avaliação dos fatores de risco para distúrbios de voz em professores e análise acústica vocal como instrumento de avaliação epidemiológica

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Raquel Aparecida Pizolato

2013-08-01

Full Text Available OBJETIVO: avaliar fatores de risco para disfonia em professores e associá-los compresença de alteração vocal. MÉTODO: 102 professores(81 mulheres e 21 homens selecionados aleatoriamente de 11 escolas do município de Piracicaba/SP, com média de idade de 42,48 anos. Um questionário sobre aspectos do ambiente e organização do trabalho, comportamento vocal, estilo de vida e sinais e sintomas de alterações vocais foi aplicado.Uma análise acústica da voz foi realizada e as variáveis avaliadas dependentes foram Frequência Fundamental e a Intensidade média vocal. Foram realizadas associações entre as variáveis do questionário com a frequência fundamental e a intensidade média e utilizaram-se os testes estatísticos: Qui-quadrado, Exato de Fisher e cálculo do OddsRatio e este é um estudo clínico prospectivo. RESULTADOS: os indivíduos do sexo masculino tiveram menos chance de apresentarem frequência fundamental da voz alterada do que o gênero feminino (p<0,0001. As professoras que lecionavam para o ensino fundamental II e médio tiveram menos chance de apresentar alteração da frequência fundamental da voz do que aquelas que lecionavam para o ensino fundamental (p=0,04. O ruído ambiente teve associação significante com a alteração da intensidade média da voz (p=0,02. CONCLUSÃO: fatores como o sexo feminino lecionar para o ensino primário e estar exposto ao ruído do ambiente de trabalho foram considerados indicadores de risco para distúrbios da voz em professores.

La cara auditiva: El reconocimiento de las personas a través de la voz

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Alba Mónica Casado Ramos

2014-04-01

Full Text Available Cuando escuchamos a alguien hablar, aunque no lo veamos ni conozcamos, obtenemos diferentes tipos de información a partir de su voz: su mensaje lingüístico, su estado emocional y también, por extraño que parezca, una imagen de sus características físicas, una especie de “cara auditiva”. Si el hablante es alguien conocido, podemos además saber quién es, es decir, podemos identificarlo únicamente por la idiosincrasia de su voz. Cuando voz y cara aparecen juntas, la información obtenida a partir de ambas modalidades sensoriales se integra para crear una imagen global y completa del hablante.

Opinião dos pais sobre a voz, características de comportamento e de personalidade de seus filhos Parents opinion on the voice and on behavior and personality characteristics of their children

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Angela von Fritsch

2011-02-01

Full Text Available OBJETIVO: verificar como os pais percebem e descrevem seus filhos com relação à voz e às características de comportamento e personalidade. MÉTODOS: participaram do estudo 66 pais de crianças entre 6 e 9 anos, de ambos os sexos, os quais responderam a um questionário com 28 questões que investigavam características de voz, comportamento e personalidade de seus filhos. RESULTADOS: os resultados indicaram que a maioria dos pais (90,9% se mostra satisfeita com o som da voz de seu filho(a. Somente 9,1% dos pais caracterizaram a voz de seu filho como sendo pior que a das demais crianças e 31,8% achou que seu filho(a fala muito mais se comparado aos colegas. Aproximadamente um quarto (22,7% dos pais observou que o volume de voz utilizado por seus filhos é aumentado. Os pais que caracterizaram seus filhos como sendo mais falantes também perceberam a voz deles como sendo mais aguda (p=0,013. O volume de voz aumentado mostrou correlação positiva com agitação (p=0,044, inquietação (p=0,005, sociabilidade (p=0,021, menos quantidade de horas dormidas (p=0,013 e extroversão (p=0,014. Crianças caracterizadas como sendo mais calmas (p=0,011 e menos argumentativas (p=0,044 são também menos falantes na comparação com outras crianças. CONCLUSÃO: em geral, os pais parecem perceber características vocais em seus filhos, têm forte tendência a considerar seus filhos sensíveis, observadores e exigentes quanto a si mesmos, além de perceberem relação entre volume de voz e características de comportamento e personalidade.PURPOSE: to check how parents perceive and describe their children with 'regard to their voice and behavior and personality traits. METHODS: the study involved the participation of 66 parents of children between 6 and 9 year old, from both genders, who answered a questionnaire with 28 questions addressing voice, behavior and personality traits of their children. RESULTS: results indicated that the majority of the parents

Efectos de la posición corporal y la sedación en la calidad de la voz

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Oishi Konari, Miriam Natsuki

2015-01-01

En el ámbito de la Otorrinolaringología, existe una situación en donde la voz juega un papel importante para tomar una decisión intraoperatoria: durante la cirugía de tiroplastia de medialización de la cuerda vocal. Tras la realización de numerosas tiroplastias de medialización con anestesia local y sedación en nuestro Servicio de Otorrinolaringología, sospechamos que el test de voz intraoperatorio no era fiable ya que la voz obtenida durante el mismo no era la misma que la obtenida por el...

Normatização de medidas acústicas da voz normal

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Araújo Simone Adad

2002-01-01

Full Text Available Introdução: A análise acústica da voz com o avanço da tecnologia digital surge como um exame complementar promissor para aumentar a precisão diagnóstica em laringologia. Objetivo: Normatização das medidas acústicas de freqüência fundamental, perturbação e ruído na voz normal de brasileiros dos sexos masculino e feminino. Forma de estudo: Clínico prospectivo. Material e Método: Pesquisa no período de março a agosto de 1997, no Ambulatório de Otorrinolaringologia do Hospital das Clínicas da Faculdade de Medicina de Ribeirão Preto da Universidade de São Paulo, com 80 voluntários da cidade de Ribeirão Preto e região, sendo 40 do sexo masculino e 40 do feminino, selecionados por meio de triagem, foram realizadas gravações digitais dos fonemas /a/, /e/ e /i/, originando uma amostra de 240 sinais acústicos submetidos ao Programa de Análise Acústica da Voz, desenvolvido na Escola de Engenharia de São Carlos da Universidade de São Paulo com obtenção das medidas acústicas. Resultados: Foram obtidos valores médios em relação a sexo e fonemas das medidas de: Freqüência fundamental, Jitter (Directional Perturbation Factor, Perturbation Variation Index, Jitter Ratio, Jitter Factor, Period Perturbation Quotient, Shimmer (Directional Perturbation Factor, Amplitude Variation Index, Amplitude Perturbation Quotient, Spectral Noise Level, Harmonic-to-noise ratio, Harmonic-to-noise ratio cepstrum, Normalized Noise Energy e Breathiness ratio. Conclusão: A normatização das medidas acústicas é necessária para conhecer melhor a voz normal. Os valores obtidos são compatíveis em sua grande maioria com à literatura existente.

Em torno da luz cristalina: clara voz de Pedro Salinas

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Cristiano Moreira

2015-06-01

Full Text Available http://dx.doi.org/10.5007/2176-8552.2016n20p147 O texto que segue pretende ler a poesia de Pedro Salinas e Jorge Guillén diante de uma perspectiva que faz da voz uma iluminação e uma resistência diante do tempo histórico e da predominância de uma leitura simples das imagens. Assim, alguns poemas escolhidos permitem uma leitura contemporânea a respeito da voz, seguindo o conceito de Stimmung recuperado por Giorgio Agamben e as lições de poesia de Paul Valéry, e formam aspectos imprescindíveis para ler a poesia destes poetas. Ao manter em sua produção uma conversação com seus predecessores, Pedro Salinas joga com o logos e faz da phoné matéria prima para sua obra.

SISTEMA DE CONTROL DE UN MANIPULADOR MECÁNICO POR DETECCIÓN DE VOZ

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Javier Darío Barrios Cárdenas

2013-01-01

Full Text Available En este trabajo se presenta el diseño e implementación del sistema de control de un manipulador mecánico por detección de voz, para la asistencia a discapacitados. Está conformado por un circuito de reconocimiento de voz que convierte las palabras en datos binarios que se guardan en una memoria RAM y al mismo tiempo se procesan por medio de un microcontrolador para que puedan ser visualizados en una pantalla LCD y enviados a través de un cable de datos al circuito de control de un manipulador mecánico quien ejecuta las órdenes producto del reconocimiento.

La inclusión educativa desde la voz de madres de estudiantes con Trastornos del Espectro Autista en una muestra chilena

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Marcela Villegas Otárola

2014-12-01

Full Text Available El objetivo del estudio es mostrar la perspectiva de madres chilenas sobre la inclusión educativa de sus hijos escolarizados en centros de educación primaria, quienes presentan un Trastorno del Espectro Autista. Se recogen evidencias, desde la voz de las familias, que pueden servir como punto de partida para reflexionar sobre cómo avanzar hacia una educación más inclusiva y cómo contribuir a mejorar los apoyos que se brindan a estudiantes con discapacidad. El estudio se enmarca en un paradigma cualitativo de investigación, utilizando entrevistas no estructuradas para acceder a la información. Se ha contado con la participación de ocho madres chilenas de la Región de Valparaíso. Los resultados muestran que la valoración de la escolarización está estrechamente relacionada con el bienestar emocional, ámbito al que se le otorga mayor relevancia que al de los resultados académicos. Se destaca la importancia de los apoyos adaptados a las necesidades del sistema familiar.

Revisión de los modelos de producción de voz después de una laringectomía total: opciones de calidad de voz

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Roberto Fernández-Baillo

2011-12-01

Full Text Available El paciente laringectomizado es aquel que debido a un proceso cancerígeno ha sido sometido a una intervención quirúrgica cuyo resultado es la extirpación total de la laringe. Como consecuencia de esta operación el paciente sufre una serie de modificaciones anatómicas que conllevan la alteración y/o pérdida de determinadas funciones. Siendo la pérdida de la voz, y por tanto de la comunicación oral, la limitación principal a la que se enfrentan estos pacientes. Es por ello, que el proceso de tratamiento y rehabilitación post-quirúrgico tiene como uno de sus objetivos principales el restablecimiento de la comunicación oral. Para ello se deberá dotar al paciente de una nueva fuente de sonido (neo-glotis, la cual tendrá que suplir o emular la función vibratoria anteriormente realizada por glotis laríngea. El objetivo de este trabajo es analizar desde una perspectiva biomecánica y acústicas los distintos tipos de voces que pueden representar una opción para el paciente laringectomizado. Se pretende mostrar las ventajas y limitaciones de cada modelo de producción, de una forma clara y objetiva, comprensible tanto para el clínico como para el paciente, con el fin de orientar en la toma de decisiones. Finalmente se realiza un análisis acústico de la voz de cuatro pacientes femeninos laringectomizadas. Cada muestra de voz se corresponde con un modelo de producción diferente: laringe artificial, prótesis fonatoria y erigmofonía.

Instrumentos aplicados en la evaluación de la voz en profesores: estudio bibliográfico

OpenAIRE

Serey,Jazmín Pérez; Araya,Virna Ortiz

2013-01-01

El objetivo de este trabajo es realizar un estudio bibliográfico focalizado en los instrumentos que se utilizan para evaluar de forma objetiva y cualitativa la voz en profesores. Se realizó un levantamiento bibliográfico de las publicaciones catalogadas en Pubmed y Scielo durante los últimos 5 años, que tuvieran relación con la evaluación de la voz en profesores. Los instrumentos utilizados en los 15 artículos encontrados muestran que un 80% de los estudios ocupan cuestionarios, 40% realiza e...

Escutando a voz de Meschonnic

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Cristina Henrique da Costa

2013-10-01

Full Text Available http://dx.doi.org/10.5007/2176-8552.2013n15p75 O presente artigo procura analisar alguns aspectos da argumentação de Henri Meschonnic em Critique du rythme, tentando mostrar que ela se apóia na decisão de não dissociação entre os diversos registros discursivos habitualmente separados uns dos outros. Tenta-se aqui compreender de que modo esta decisão, que não está a serviço de um estilo literário, e sim de uma ideia diretriz – a do sujeito, desenvolve-se eficientemente. É porque o sujeito está na fonte dos discursos que ele necessariamente tem expressão em diversos gêneros. Da mesma forma, por ser a condição de possibilidade de todo discurso sobre o sujeito, só a decisão de continuidade entre a fala teórica, a tomada crítica e o pensamento poético é capaz de tornar audível a função organizadora subjetiva dentro da linguagem. Desta maneira, o próprio discurso de Meschonnic sustém-se ao mesmo tempo num esforço de crítica das idéias preconcebidas sobre a linguagem e a poesia, e num esforço teórico-poético para repensar o discurso e o sentido. Sob este ângulo, são então abordadas as noções poéticas de ritmo, de oralidade e de voz, tentando o artigo mostrar a grande originalidade e o poder de transformação que tais noções imprimem ao olhar da teoria literária sobre si mesma. Palavras chave: ritmo – discurso – historicidade – sujeito.   Résumé Le présent article cherche à analyser quelques aspects de l’argumentation d’Henri Meschonnic dans Critique du rythme, en essayant de montrer qu’elle repose sur la décision de la non dissociation entre différents registres discursifs habituellement séparés. On tente de comprendre ici sous quel mode cette décision, qui n’est pas au service d’un style littéraire, mais au service d’une idée directrice - celle du sujet, déploie son efficacité. C’est parce que le sujet est à la source des discours, qu’il ne peut que se décliner en

Correlação da qualidade de vida e voz com atividade profissional Correlation between voice and life quality and occupation

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Ana Lúcia Spina

2009-04-01

Full Text Available As disfonias podem comprometer a qualidade da comunicação e, por conseqüência, a relação social do indivíduo e assim afetar sua qualidade de vida. Existe hoje necessidade de protocolos objetivos para avaliação da qualidade vocal que mensurem suas implicações na qualidade de vida do paciente. OBJETIVOS: Relacionar qualidade de vida e voz com o grau de disfonia e o uso profissional da voz em um grupo de pacientes disfônicos. MATERIAL E MÉTODO: Realizou-se estudo clínico prospectivo aplicando-se protocolo internacional para avaliar a qualidade de vida e voz em um grupo de pacientes disfônicos. Realizou-se tratamento estatístico dos resultados considerando-se não-distinção entre profissionais da voz e não-profissionais da voz e, em seguida, considerando-se esta distinção profissional. RESULTADOS: A disfonia afetou a qualidade de vida em todos os indivíduos. Não houve diferença estatística entre os grupos, profissionais da voz e não-profissionais da voz, quanto ao grau de disfonia. Houve correlação entre qualidade de vida e grau de disfonia, no entanto, considerando-se os grupos separadamente, esta correlação foi significativa apenas no grupo de sujeitos não-profissionais da voz. CONCLUSÃO: A disfonia afetou a qualidade de vida em todos os sujeitos independente do uso profissional da voz.Dysphonia may impair the quality of communication and social relations of people, thereby directly affecting quality of life. It is common knowledge amongst professionals involved with the treatment of voice disorders the need for objective protocols to evaluate voice quality and measure its impact on the individual's quality of life. AIM: To associate life quality with the degree of dysphonia and professional voice use in a group of dysphonic patients. MATERIALS AND METHODS: A prospective clinical study was undertaken with a group of dysphonic patients using an internationally validated voice-related quality-of-life protocol. A

La crisis de la escuela en la formación de la juventud: La voz de los estudiantes universitarios

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José Manuel Juárez Núñez

2014-01-01

Full Text Available Este artículo da la voz a los alumnos, actores centrales sin duda del acto educativo, que tratan de releer su experiencia escolar vivida a lo largo de sus años de escolares ayudándose de las teorías analizadas, aprendidas, y asimiladas en el transcurso del módulo “Educación y Cultura” de la carrera de Sociología. Es también un intento de poner en práctica los conocimientos construidos a lo largo no sólo de este trimestre, sino de los diferentes módulos cursados en la carrera, de manera que puedan hacer un alto en el camino y reflexionar sobre el camino escolar recorrido. Muestra la crisis de la escolaridad vivida por ellos mismos y reflexionada a partir de los conocimientos adquiridos en su recorrido universitario.

Identification of a major IP5 kinase in Cryptococcus neoformans confirms that PP-IP5/IP7, not IP6, is essential for virulence

OpenAIRE

Li, Cecilia; Lev, Sophie; Saiardi, Adolfo; Desmarini, Desmarini; Sorrell, Tania C.; Djordjevic, Julianne T.

2016-01-01

Fungal inositol polyphosphate (IP) kinases catalyse phosphorylation of IP3 to inositol pyrophosphate, PP-IP5/IP7, which is essential for virulence of Cryptococcus neoformans. Cryptococcal Kcs1 converts IP6 to PP-IP5/IP7, but the kinase converting IP5 to IP6 is unknown. Deletion of a putative IP5 kinase-encoding gene (IPK1) alone (ipk1?), and in combination with KCS1 (ipk1?kcs1?), profoundly reduced virulence in mice. However, deletion of KCS1 and IPK1 had a greater impact on virulence attenua...

Servicios de voz para la gestión de la información

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Díez Carrera, Carmen

1996-12-01

Full Text Available Voice facilities are one of the most innovative means of access to information systems, based on computer processing of it, in order to achieve systems of speech recognition and synthesis. This article analyses it in its physiological, physical and linguistic aspects as well as computer processing. It finishes with a collection of application examples.

Los servicios de voz constituyen uno de los medios más novedosos de acceso a los sistemas de información, basados en el tratamiento informático de la misma para conseguir sistemas de reconocimiento y síntesis de voz. El presente artículo la analiza en sus diversos aspectos -fisiológico, físico y lingüístico-, su tratamiento informático y concluye con un muestrario de aplicaciones.

Informação, educação e comunicação em saúde: análise das concepções dos coordenadores das campanhas de voz no distrito federal

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Rodrigo Dornelas

2014-03-01

Full Text Available Objetivo: compreender e discutir as concepções de informação, educação e comunicação (IEC em saúde dos fonoaudiólogos que coordenaram e desenvolveram as campanhas de voz em Brasília, nos anos 2009 e 2010.Métodos: pesquisa qualitativa que utilizou roteiro de perguntas semiestruturado que tratava da organização da campanha da voz em Brasília. As entrevistas foram realizadas com os organizadores das campanhas da voz nos anos de 2009 e 2010, totalizando 08 entrevistas. O material das entrevistas foram gravados e posteriormente transcritos, para a análise foram seguidas as etapas da Análise de Conteúdo (AC. A discussão foi efetuada com base no referencial teórico de informação, educação e comunicação em saúde.Resultados: a Informação em Saúde é vista como a descrição do funcionamento do aparelho fonador e não como dados disparadores necessários para o planejamento e execução de ações eficazes para a campanha; a Educação em Saúde, como repasse de informações e não como um processo de construção coletivo a respeito dos cuidados necessários para o bem estar vocal; e, a Comunicação em saúde, limita-se aos espaços da mídia e não como estratégia de construção de comunicação partindo do conhecimento da população a respeito do assunto.Conclusão: o conceito IEC está presente na campanha de voz em Brasília, porém a concepção que a cerca por parte dos responsáveis pela execução e elaboração das ações está longe de um consenso. A dificuldade em falar sobre informação, educação e comunicação em saúde reflete na fragilidade teórica em que a campanha de voz está ancorada.

VEZ E VOZ NA LINGUAGEM: O SUJEITO SOB O EFEITO DE SUA FALA SINTOMÁTICA

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Maria Francisca Lier-DeVitto

2010-01-01

Full Text Available “Vez e voz na linguagem” é expressão que refere a condição na qual o sujeito falante supõe poder controlar a própria fala. Este texto procura problematizar a inversão imaginária produzida pela presença de sintoma na fala, numa reflexão que coloca em cena o efeito “social” – de marginalização/isolamento – que se produz na escuta do outro e o efeito de “destituição subjetiva” – de perda de vez e voz – que se produz na escuta do próprio falante. Afasias e demências – quadros clínicos que incidem na velhice – são discutidas de um ponto de vista lingüístico e são traçadas diferenças relativas às manifestações sintomáticas e seus efeitos subjetivos. Nessa perspectiva é que se apresentam, de um lado, a “clínica de linguagem” como espaço de tomar a vez e a voz e, de outro lado, o de “centros de convivência” como espaços privilegiados de inclusão social. Palavras-chave: afasia; demência; linguagem.

Fatores de risco e emocionais na voz de professores com e sem queixas vocais

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Denise Batista da Costa

2013-08-01

Full Text Available OBJETIVO: analisar a interferência dos fatores de riscos e emocionais na voz de professores com e sem queixa. MÉTODO: a amostra foi composta de 44 professores. Utilizou-se uma ficha com dados pessoais e profissionais, três questionários referentes aos aspectos vocais e dois questionários para dados relacionados à emoção, sobretudo ansiedade, além da coleta de voz para análise perceptivo-auditiva. Os grupos foram divididos a partir do número de sintomas relatados, estabelecendo um número de 22 voluntários no grupo de Professores Sem Queixa (PSQ e 22 no grupo Professores Com Queixas (PCQ, sendo deste grupo, os indivíduos que relataram mais de três sintomas vocais. Os dados foram analisados estatisticamente. RESULTADOS: a média do número de sintomas descritos no QSSV foi de 5,7 (±2,8 para os PCQ e de 0,8 (±0,9 para os PSQ. Os PSQ referiram uma melhor autoavaliação vocal (p= 0,01 e os PCQ afirmaram possuir um maior comprometimento em sua voz (p= 0,001. O grupo PSQ obteve os maiores valores nos escores do QVV-Físico (p=0,0007 e QVV-Total (p= 0,0006. Os PCQ obtiveram maiores valores no IDV-Total (p=0,0003 e IDV-Orgânico (p=0,0006, e um maior comprometimento emocional, com SRQ de 5,7 (±3,9 e IDATE 42,5 (±12,7. A partir da avaliação perceptivo-auditiva, os PCQ apresentaram um desvio vocal moderado com presença de rugosidade, soprosidade e tensão na voz, enquanto os PSQ evidenciam um desvio leve em todos os parâmetros. CONCLUSÃO: os professores com queixas vocais estão expostos a mais fatores de riscos, além de relatarem mais sintomas e comprometimento vocais, bem como emocionais.

As Campanhas da Voz no percurso da Informação, Educação e Comunicação em Saúde – uma (revisão reflexiva.

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Rodrigo Dornelas do CARMO

2014-12-01

Full Text Available A Campanha da Voz proposta pela Sociedade Brasileira de Fonoaudiologia (SBFa é uma ação estratégica em Saúde que tem como objetivo promover os cuidados com a voz junto à população. Surgiu com um enfoque na prevenção, a partir do aumento da incidência de câncer de laringe na população brasileira, sendo que atualmente aborda diversos temas e estratégias na busca pela Promoção da Saúde, representando, portanto uma importante ação educativa promovida no âmbito da Fonoaudiologia e da Saúde Coletiva, e que embora muito valorizada pelos fonoaudiólogos, ainda tem sido pouco estudada. Neste sentido, este artigo tem como objetivo realizar uma revisão crítica reflexiva sobre as campanhas da voz promovidas pela Sociedade Brasileira de Fonoaudiologia (SBFa no contexto da Informação, Educação e Comunicação em Saúde. Entender os reflexos da campanha está relacionado à possibilidade de modificação das estratégias pedagógicas utilizadas, sustentada pela instrumentalização teórica estabelecida. Isso demonstra a necessidade de uma maior instrumentalização por parte dos profissionais envolvidos neste processo para que possa garantir a qualidade da proposta de uma campanha em saúde. Neste sentido a revisão dos conceitos trabalhados e a forma como são colocados à população nos direciona ao real objetivo das campanhas de saúde, ligado à promoção da saúde, refletindo na qualidade de vida da população.

Qualidade de vida relacionada à voz de professores universitários Voice-related quality of life of university teachers

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Mariana Zerbetto Fabrício

2010-04-01

Full Text Available OBJETIVO: observar a qualidade de vida relacionada à voz dos docentes da Faculdade de Medicina de Ribeirão Preto da Universidade de São Paulo (FMRP-USP, além de descrever seus conhecimentos referentes à saúde vocal, fornecendo assim, dados que possam motivar futuras ações para prevenção e tratamento da disfonia. MÉTODOS: foram utilizados o Protocolo de Qualidade de Vida em Voz (QVV e um questionário que investigou sintomas vocais, uso da voz e atitudes diante dos sintomas. RESULTADOS: registrou-se que 82% dos docentes participantes atingiram escores iguais a 100 para o domínio sócio-emocional, 38% para o domínio físico e 38% para o escore total. Uma grande parte (31% considera sua voz "muito boa", mas deve-se considerar que 26% dos entrevistados não avaliaram sua voz. Com relação às atitudes que os docentes tomam frente a um problema vocal, 53% relatam diminuir o uso da voz. Os sintomas de maior incidência relatados pelos docentes foram garganta seca, tosse e perda de voz. CONCLUSÃO: o presente estudo mostrou relatos de satisfação vocal e alto índice de qualidade de vida, porém observou-se uma prevalência elevada de sintomas vocais, demonstrando a necessidade de ações preventivas e de orientação vocal para esses professores.PURPOSE: to observe the voice-related quality of life of teachers from the Ribeirão Preto Medical School, University of São Paulo (FMRP/USP, to describe their knowledge on vocal health, and to provide data that can motivate future actions for preventing and treating dysphonia. METHODS: data collection instrument was Quality of Life and Voice Protocol (QLV. It was also used a questionnaire that investigated vocal symptoms, vocal use and attitudes before the symptoms. RESULTS: 82% of the teachers who participated in the survey achieved scores equal to 100 for the socio-emotional domain, 38% for the physical domain and 38% for the total score. A large portion (31% believe his voice "very good

Algumas anedotas sobre Demóstenes: uma releitura

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Maddalena Vallozza

2013-06-01

Full Text Available Muitas das anedotas sobre Demóstenes estão relacionados a seus problemas de voz e a suas dificuldades no momento da hypokrisis. Eu proponho uma reinterpretação das páginas em que eles nos são transmitidos: de Quintiliano (11, 3, a principal testemunha, a Cícero (Orator 26 e 56-58, Brutus 142, De Oratore I 261 e III 213, do autor da seção sobre Demóstenes nas Vidas dos Dez Oradores (844 d-845 b à Vida de Demóstene, de Plutarco. Com base nisso, particularmente graças a Plutarco, que cita Hermipo e Demétrio de Fáleros, é possível formular a hipótese de que a tradição nasceu no Perípato, na área de interesses pela hypokrisis que demonstram o perdido Perì hypokríseos de Teofrasto e os fragmentos da Retórica de Demétrio de Fáleros.

HISTÓRIAS DE CRIANÇAS COM DEFICIÊNCIA: POR UM JORNALISMO QUE NARRA E DÁ VOZ

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Giselle Freire Borges Coelho

2017-06-01

Full Text Available Este artigo propõe discussões sobre como, por meio da compreensão de narrativas míticas, dialógicas e produtoras de conhecimento, seremos capazes de contar histórias e tecer narrativas mais humanas e ternas no exercício do jornalismo. As narrativas míticas são histórias compartilhadas por toda a humanidade na tentativa de significar e dar respostas às questões humanas mais profundas. Argumenta-se, então, como as narrativas jornalísticas, a exemplo das míticas, podem tornar visíveis questões importantes como o reconhecimento das crianças com deficiência de modo inclusivo, com o objetivo de exercer real influência em nossa sociedade, e criar uma realidade, mais justa e igualitária, baseada no princípio do respeito às diferenças. Tendo como base teórica o pensamento de Carl Jung, Joseph Campbell, Karen Armstrong, Hannah Arendt, Martin Buber e Cremilda Medina, o texto traz indicações de como cultivar a compreensão na prática do jornalismo. Tomamos, como exemplo, os textos da jornalista Eliane Brum que quebram o paradigma do jornalismo tradicional, alterando seu foco e dando voz às pessoas antes esquecidas, narrando com afeto o que é estar vivo e afirmando o protagonismo e a importância de cada ser humano. São analisadas, ainda, duas matérias da Revista Crescer sobre crianças com deficiências.

VoIP Security

OpenAIRE

Fontanini, Piero

2008-01-01

VOIP or Voice Over Internet Protocol is a common term for phone service over IP based networks. There are much information about VoIP and some of how VoIP can be secured. There is however no standard for VoIP and no general solution for VoIP Security. The security in VoIP systems today are often non existing or in best case weak and often based on proprietary solutions. This master thesis investigates threats to VoIP system and describes existing alternatives for securing Vo...

A campanha da voz em dois jornais brasileiros de grande circulação The voice campaign in the two major Brazilian newspapers

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Regina Zanella Penteado

2002-12-01

Full Text Available Na sociedade atual, os meios de comunicação de massa produzem, selecionam, excluem e transformam aspectos da realidade reproduzindo-a parcialmente e formando a opinião pública. Na área da saúde, os meios de comunicação são destacados para a educação e promoção da saúde da população. Isso conduz à reflexão sobre a mediação da realidade exercida pelos meios de comunicação e como os temas da saúde são abordados na mídia. OBJETIVO: Analisar as notícias sobre a Campanha da Voz nos jornais de grande circulação. MÉTODO: Análise Documental das notícias sobre a Campanha da Voz publicadas nos jornais "O Estado de S. Paulo" e "Folha de S. Paulo", entre 13 e 20/04/2002. A análise considera aspectos quantitativos e qualitativos das reportagens e leva em conta a sua contribuição para processos educativos condizentes com a promoção da saúde. RESULTADOS: Somente a "Folha" publicou duas reportagens sobre a campanha. Evidenciam-se recursos apelativos dramáticos e a ênfase na doença. As abordagens de caráter comportamental, normatizador, tecnicista e tecnológico referenciam a prevenção e tratamento. Há reforço de estereótipos e banalização da complexidade das ações das especialidades envolvidas. Discute-se aspectos destas especialidades e das concepções que as fundamentam, bem como do processo de produção da notícia implicado nas problemáticas evidenciadas. CONCLUSÃO: Em se tratando da Campanha da Voz, as notícias publicadas pouco contribuem para a construção de processos educativos em saúde condizentes com a promoção da saúde. Maiores estudos devem ser feitos acerca do papel dos meios de comunicação junto à promoção da saúde da população.In today society mass communication produces, selects, excludes and transforms reality, thus reproducing it partially and forming public opinion. In the area of health communication means should bring education and promotion of public health. This makes us

Securing VoIP keeping your VoIP network safe

CERN Document Server

(Bud) Bates, Regis J Jr

2015-01-01

Securing VoIP: Keeping Your VoIP Network Safe will show you how to take the initiative to prevent hackers from recording and exploiting your company's secrets. Drawing upon years of practical experience and using numerous examples and case studies, technology guru Bud Bates discusses the business realities that necessitate VoIP system security and the threats to VoIP over both wire and wireless networks. He also provides essential guidance on how to conduct system security audits and how to integrate your existing IT security plan with your VoIP system and security plans, helping you prevent

Impact of artefact removal on ChIP quality metrics in ChIP-seq and ChIP-exo data.

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Thomas Samuel Carroll

2014-04-01

Full Text Available With the advent of ChIP-seq multiplexing technologies and the subsequent increase in ChIP-seq throughput, the development of working standards for the quality assessment of ChIP-seq studies has received significant attention. The ENCODE consortium’s large scale analysis of transcription factor binding and epigenetic marks as well as concordant work on ChIP-seq by other laboratories has established a new generation of ChIP-seq quality control measures. The use of these metrics alongside common processing steps has however not been evaluated. In this study, we investigate the effects of blacklisting and removal of duplicated reads on established metrics of ChIP-seq quality and show that the interpretation of these metrics is highly dependent on the ChIP-seq preprocessing steps applied. Further to this we perform the first investigation of the use of these metrics for ChIP-exo data and make recommendations for the adaptation of the NSC statistic to allow for the assessment of ChIP-exo efficiency.

Evaluación del impacto de los mecanismos de control de error en la calidad de servicio de telefonía IP basado en Asterisk sobre una red inalámbrica de banda ancha en la provincia de Tayacaja - Huancavelica

OpenAIRE

Rosario Villarreal, Marco Aurelio

2014-01-01

En la presente tesis de maestría de telecomunicaciones titulada “Evaluación del Impacto de los Mecanismos de Control de Error en la Calidad de Servicio de Telefonía IP basado en Asterisk sobre una Red Inalámbrica de Banda Ancha en la Provincia de Tayacaja - Huancavelica” se describe el proceso y los elementos de la transmisión de VoIP en las redes LAN inalámbricas, se evalúa los diversos mecanismos de control de error existentes y particularmente se indica el más adecuado para la red LAN ina...

APROXIMACIÓN DE LA CALIDAD DE VOZ Y COBERTURA EN UNA RED GSM DE EMERGENCIA

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Elvis Eduardo Gaona García

2014-01-01

Full Text Available En este documento se muestran los resultados obtenidos al medir los parámetros de calidad de voz en una solución propuesta de telecomunicaciones para la atención de desastres en situaciones de emergencia, haciendo uso de software libre para interconectar llamadas, protocolos de comunicaciones empleados en las redes GSM (Global System Mobile en la banda DCS-1800 (Digital Cellular Service - 1800MHz, que facilita el uso de cualquier terminal móvil comercial, utilizando un USRP (Universal Software Radio Peripheral en conjunto con sistema de telefonía IP basado en Asterisk. El USRP se encarga de emular la operación de una BTS (Base Transceiver Station al ejecutar las funciones de un PBX (Private Branch Exchange, permitiendo la coordinación de las entidades responsables de responder y atender este tipo de emergencias. Las mediciones del desempeño de la red se realizaron a partir de tres parámetros probabilísticos: GoS (Grade of service, DCR (Dropped Call Rate y MOS (Mean Opinion Score. Con el uso de 8 terminales y escogiendo un GoS del 2% se generó un tráfico de hasta 3,6 Erlang. Esta medición se realizó empleando modelos probabilísticos de Erlang B. Se realiza el comparativo de la cobertura de la red aplicando el modelo Okumura-Hata sin el uso de amplificadores.

Tratamento dos distúrbios da voz na doença de Parkinson: o método Lee Silverman

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Dias Alice Estevo

2003-01-01

Full Text Available Alterações discretas na qualidade da voz e da articulação podem ser observadas em fases relativamente iniciais da doença de Parkinson (DP. As alterações da voz e da fala na DP constituem, em conjunto, o que se denomina disartria hipocinética ou disartrofonia e caracterizam-se por monotonia e redução da intensidade da voz, articulação imprecisa e distúrbios do ritmo. Recentemente, foram relatados resultados favoráveis através de método de tratamento intensivo e dirigido especificamente para o tratamento da voz na DP, denominado Lee Silverman Voice Treatment (LSVT®. O objetivo essencial desse método é aumentar a intensidade vocal através do incremento do esforço fonatório. O presente estudo teve por objetivo a caracterização das anormalidades vocais (qualidade vocal, padrão articulatório e inteligibilidade em um grupo de pacientes com DP e a avaliação da resposta terapêutica obtida pela administração do método Lee Silverman. A comparação dos dados de análise acústica, bem como da análise perceptivo-auditiva nos períodos pré e pós-tratamento mostraram modificações estatisticamente significantes após o tratamento. Embora o padrão articulatório tenha se mantido impreciso, os benefícios obtidos pelo tratamento na melhora da qualidade vocal e, sobretudo, na intensidade vocal favoreceram a qualidade da comunicação oral, reduziram os sintomas negativos e adequaram a qualidade vocal às necessidades pessoais e sociais dos indivíduos.

A pesquisa em técnica vocal, voz e canto em Práticas Interpretativas no Brasil: Análise dos resumos das dissertações

Directory of Open Access Journals (Sweden)

Fábio Miguel

2015-06-01

Full Text Available Discorre-se acerca de uma das partes do trabalho “A pesquisa em técnica vocal, voz e canto: estado da arte” realizada em 2012-2014 pelo GEPPEVOZIA (Grupo de Estudo, Prática e Pesquisa em Voz do Instituto de Artes da UNESP em que objetivamos conhecer o estado da arte na temática técnica vocal, voz e canto em diferentes áreas do conhecimento. Apresentaremos os resultados da análise da pesquisa nas áreas de Música e Artes a partir dos resumos de dissertações de Mestrado que tratam dessa questão. A busca no portal da CAPES deu-se por palavras-chave. Focalizamos, neste texto, a análise dos resumos cujos estudos estão relacionados direta ou indiretamente a práticas interpretativas. Os resumos apresentam algumas inconsistências em sua elaboração, contudo é possível, ao examiná-los, perceber quais são as tendências dos pesquisadores na área de voz.

Localitzador Gràfic de Direccions IP 'IpLocInspector'

OpenAIRE

Ordóñez Chapado, Miguel

2006-01-01

En aquest treball s'ha desenvolupat una aplicació capaç de localitzar adreces IP. En este trabajo se ha desarrollado una aplicación capaz de localizar direcciones IP. In this work an application was developed capable of locating IP addresses.

Construcción macrotextual y cancionero amoroso (Un acercamiento analítico a "La voz a ti debida" de Pedro Salinas)

OpenAIRE

Corencia Cruz, Joaquín

2008-01-01

La tesis Construcción macrotextual y cancionero amoroso. Unacercamiento analítico a La voz a ti debida de Pedro Salinas. Fue leídapor Joaquín Corencia Cruz en la Sala de Juntas de la Facultad deFilología de la Universidad de Valencia (España) el 7 de noviembre de2008.El trabajo investigador se desarrolla a lo largo de nuevecapítulos. En el primero se produce una introducción a la tesisrevisando desde la trayectoria vital y profesional de Pedro Salinas acómo el macrotexto poético de La voz se ...

Voz antipasiva en lenguas nominativo-acusativas. El caso del purépecha

OpenAIRE

Chamoreau, Claudine

2008-01-01

International audience; Tradicionalmente, la voz antipasiva ha sido asociada con las lenguas ergativo-absolutivas (Silverstein 1976; Dayley 1990; Cooreman 1994: 50; Dixon 1994:144 y 147), y sólo pocos autores han mencionado su presencia en las lenguas nominativo-acusativas (Heath 1976: 210; Givón 2001 [1984]: 168; Bogard 1999, 2008; Nouguier Voisin 2002, 2005; Polinsky 2005: 438). El objetivo de este trabajo es mostrar la existencia de construcciones antipasivas en purépecha, lengua nominativ...

Voz cantada e a constituição da relação mãe-bebê Singing voice and the constitution of mother/baby relationship

Directory of Open Access Journals (Sweden)

Enio Lopes Mello

2009-03-01

Full Text Available TEMA: refletir sobre uma faceta da constituição da relação mãe-bebê, que se fez presente no uso criativo da voz cantada da mãe, na comunicação com o seu bebê. PROCEDIMENTOS: o único sujeito desse estudo é uma mãe, que se submeteu a oito sessões de terapias corporais associadas à emissão da voz cantada, sempre dirigidas ao bebê; as sessões transcorreram com a possibilidade de expressão livre pela fala e gesto da mãe e a escuta do terapeuta. RESULTADOS: o quadro que a mãe apresentava em relação ao seu bebê, no início do tratamento, se encaixa na descrição de depressão pós-parto. Após as sessões, a mãe conseguiu estabelecer contato com seu bebê, de modo prazeroso; por meio da emissão da voz cantada, ela estabeleceu a primeira forma de comunicação e não mais apresentou o quadro de dor e perda da voz. CONCLUSÃO: a possibilidade de reconhecimento, do bebê por sua mãe, teve a corporeidade como aliada, na conjunção dos corpos da mãe e do bebê, o que favoreceu o estabelecimento de uma comunicação com sintonia de ritmos, por meio da entoação de música cantada, que levou à constituição do bebê enquanto pessoa integrada.BACKGROUND: to address one aspect of mother/baby relationship, that arises from the use of singing voice in their communicative process. PROCEDURE: the subject of this case study is a mother who undergoes eight sessions of body therapy (massage and exercises associated to the utterance of singing voice, always directed to the baby; the sessions offered the possibility of free expression through the mother's use of gestures and speech along with the therapist' listening. RESULTS: in the beginning of treatment, the reaction of the mother towards her baby fits precisely in postpartum depression description. After the sessions, she was able to keep a most pleasant contact with her baby; by means of the singing voice, she has got the first way of communication with her child and either pain or

Medios y Salud Pública: La voz de los adolescentes

Directory of Open Access Journals (Sweden)

Luz Neira Parra

2002-05-01

Full Text Available El presente trabajo es una parte del Informe Regional Venezolano de la investigación "Medios y Salud Pública: La Voz de los Adolescentes", Proyecto COMSALUD, auspiciado por la Organización Panamericana de la Salud (OPS, la Federación Latinoamericana de Facultades de Comunicación Social (FELAFACS y la Organización de las Naciones Unidas. Fue realizado entre septiembre del 2001 y abril del 2002 en base al protocolo acordado por las 12 instituciones universitarias participantes de acuerdo a la planificación pautada en la ciudad de Ibarra, Ecuador en junio del 2001. La Universidad del Zulia, de Maracaibo, Venezuela, viene participando en el proyecto COMSALUD desde 19977con el "Estudio comparativo de mensajes relacionados con la salud en los medios masivos Latinoamericanos". En base al proyecto presentado por la OPS, esta etapa de la investigación se realizó por medio de la técnica de los grupos focales (investigación cualitativa a poblaciones de adolescentes de las áreas urbanas y y rurales del estado Zulia. Se realizaron 16 grupos focales en los cuales se convocaron adolescentes distribuidos por sexo, en dos grupos de edades y procedentes de los estratos socioeconómicos medio y bajo. Partiendo de la concepción de que los medios de comunicación social son una poderosa herrramienta de intervención social y como tal vehículos estratégicos para la difusión de mensajes sobre salud tendientes a incidir en el nivel de información y las actitudes de las audiencias a quienes van dirigidos. El propósito de la investigación es utilizar los resultados como insumos para el desarrollo de políticas públicas que propicien el diseño de programas de comunicación y salud dirigidos a adolescentes.

AVALIAÇÃO DA ORIENTAÇÃO SISTEMATIZADA NA REABILITAÇÃO DA VOZ DE PACIENTES LARINGECTOMIZADOS

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Olga Maimoni Aguillar

Full Text Available Nenhuma cirurgia realizada atualmente produz mais profundas alterações fisiológicas e psíquicas que a laringectomia. Estas pessoas, após a cirurgia, vêem-se impossibilitadas de falar, respiram através da traqueostomia, tem alteração do olfato e do paladar e, na maioria das vezes, suspeitam de que possuem câncer. O propósito deste trabalho, é testar o método de aprendizagem da voz esofágica com a finalidade de ajudar a reabilitação do paciente laringectomizado. Concluímos que o método utilizado para adquirir a voz esofágica teve resultados satisfatórios; que o enfermeiro é profissional capaz de orientar esse aprendizado e que além do problema de comunicação, muitos outros afligem o paciente laringectomizado.

Voz e disfunção temporomandibular em professores Voice and temporomandibular joint disorders in teachers

Directory of Open Access Journals (Sweden)

Ilza Maria Machado

2009-12-01

Full Text Available OBJETIVO: verificar a presença e possível correlação entre alteração vocal e DTM, em professores, a partir de dados de avaliação autorreferida, fonoaudiológica, otorrinolaringológica e odontológica. MÉTODOS: participaram deste estudo, 29 professores de uma escola de rede pública do ensino fundamental e médio do município de Sorocaba - SP. Os professores responderam questionário para levantamento de alteração vocal, e de disfunção temporomandibular (DTM. Foram realizadas quatro avaliações: perceptivo-auditiva; otorrinolaringológica; motricidade orofacial e odontológica. A menção a três ou mais sintomas no questionário determinou "presença" de queixa de voz e de DTM. As avaliações: perceptivo-auditiva e otorrinolaringológica concluíram a "ausência" e "presença" de alteração de voz e de laringe. Nas avaliações da motricidade orofacial e odontológica foi considerada DTM quando registrados três ou mais sinais e/ou sintomas, sendo indispensável à presença de dor. Na análise estatística dos dados, foram empregados: teste de Igualdade de Duas Proporções, teste exato de Fisher e de concordância Kappa. RESULTADOS: dentre os participantes, 82,8% fizeram autorreferência à alteração vocal e 62,1% de sintomas de DTM; 51,7% apresentaram alteração de voz na avaliação otorrinolaringológica e 65,5%, alteração de DTM na avaliação odontológica. Na comparação da avaliação de alteração de voz e DTM foi registrada correlação significante presente na avaliação perceptivo-auditiva da voz e de motricidade orofacial para DTM, e com tendência a significância na aplicação do questionário. CONCLUSÃO: os resultados apontam na direção de confirmar a presença de alteração de voz e DTM no grupo de professores pesquisado e correlação entre os mesmos.PURPOSE: to check the presence and possible correlation between vocal disorders and temporomandibular joint disorders (TMJD in teachers, from self

Evaluation of IP Portfolios

DEFF Research Database (Denmark)

Søberg, Peder Veng

2009-01-01

As a result of an inquiry concerning how to evaluate IP (intellectual property) portfolios in order to enable the best possible use of IP resources within organizations, an IP evaluation approach primarily applicable for patents and utility models is developed. The developed approach is useful...... of the organization owning the IP....

Musicalidade e transmissao da voz: James, John e Lucia Joyce // Musicality and transmission of the voice: James, John and Lucia Joyce

Directory of Open Access Journals (Sweden)

Renata Mattos

2012-06-01

Full Text Available Este artigo tem como objetivo trabalhar a temática da voz, da música e do traço em James Joyce, seu pai John e sua filha Lucia com o intuito de pensar as diferentes saídas possíveis face à questão do sintoma da carência paterna, seja pela elevação ao sinthoma pela escrita de uma obra literária no caso de Joyce, seja pela tentativa de manejo da voz através da dança, no caso de Lucia. Propomos tomar a escrita de James Joyce naquilo que ela nos oferece para pensar a relação entre uma escrita possível da voz e a invocação ao Pai, detendo-nos na transmissão da voz efetuada nestas três gerações da família Joyce, no que cada um deles pôde, de maneiras singulares, criar face ao real. // The aim of this paper is to work the thematic of the voice, the music and the trait in James Joyce, his father John and his daughter Lucia in order to think about the question of the elevation of the symptom of the lack of the father through the writing of James Joyce in his literary work as well as though the relation of Lucia with the dance. Our proposal is to reflect about the writing of Joyce to think about the relation between a possible writing of the voice and the invocation to the Father, as well as the transmission of the voice made in these three generations of the Joyce family in what each one of them could, in different ways, create guided by the real.

PVM and IP multicast

Energy Technology Data Exchange (ETDEWEB)

Dunigan, T.H.; Hall, K.A.

1996-12-01

This report describes a 1994 demonstration implementation of PVM that uses IP multicast. PVM`s one-to-many unicast implementation of its pvm{_}mcast() function is replaced with reliable IP multicast. Performance of PVM using IP multicast over local and wide-area networks is measured and compared with the original unicast implementation. Current limitations of IP multicast are noted.

A voz desenhada e a vez colorida da infância

OpenAIRE

Martins, Teresa Alexandra Fonseca Moreira Lobo

2009-01-01

Dissertação de mestrado em Estudos da Criança (área de especialização em Tecnologias da Informação e Comunicação) "A voz desenhada e a vez colorida da Infância" constitui uma análise sociológica do desenho infantil. A Sociologia da Infância possibilita uma maior visibilidade à infância e, os desenhos das crianças são considerados como formas de expressão simbólica - de um grupo social do tipo geracional. A "tela" onde conjuntamente desenhamos, assenta em metodologias participativas ...

Mobile IP and protocol authentication extension

OpenAIRE

Nguyen, Phuc V.

2011-01-01

Mobile IP is an open standard, defined by the Internet Engineering Task Force (IETF) RFC 3220. By using Mobile IP, you can keep the same IP address, stay connected, and maintain ongoing applications while roaming between IP networks. Mobile IP is scalable for the Internet because it is based on IP - any media that can support IP can support Mobile IP.

Impact of genome assembly status on ChIP-Seq and ChIP-PET data mapping

Directory of Open Access Journals (Sweden)

Sachs Laurent

2009-12-01

Full Text Available Abstract Background ChIP-Seq and ChIP-PET can potentially be used with any genome for genome wide profiling of protein-DNA interaction sites. Unfortunately, it is probable that most genome assemblies will never reach the quality of the human genome assembly. Therefore, it remains to be determined whether ChIP-Seq and ChIP-PET are practicable with genome sequences other than a few (e.g. human and mouse. Findings Here, we used in silico simulations to assess the impact of completeness or fragmentation of genome assemblies on ChIP-Seq and ChIP-PET data mapping. Conclusions Most currently published genome assemblies are suitable for mapping the short sequence tags produced by ChIP-Seq or ChIP-PET.

ejIP: A TCP/IP Stack for Embedded Java

DEFF Research Database (Denmark)

Schoeberl, Martin

2011-01-01

present the design and implementation of a network stack written entirely in Java. This implementation serves as an example how to implement system functions in a safe language and gives evidence that Java can be used for operating system related functionality. The described TCP/IP stack ejIP has already...

La voz del alumnado y la inclusión educativa: una aproximación democrática radical para el aprendizaje intergeneracional

Directory of Open Access Journals (Sweden)

Michael Fielding

2011-01-01

Full Text Available El ámbito de la voz del alumnado ha tenido un amplio abanico de desarrollos en los últimos veinte años, pero existen problemas sin resolver, principalmente los problemas de inclusión. Frente a las distorsiones endémicas de los enfoques educativos dominantes neoliberales y basados en el mercado, se propone una alternativa más generosa y humana, centrada en la persona y en la comunidad democrática. Sugiero diez elementos teóricos que proporcionan un marco inicial para la voz del alumnado, para la inclusión y para promover el aprendizaje intergeneracional como tarea central de la democracia entendida como forma de vida.

APLIKASI SERVER VIRTUAL IP UNTUK MIKROKONTROLER

OpenAIRE

Ashari, Ahmad

2008-01-01

Selama ini mikrokontroler yang terhubung ke satu komputer hanya dapat diakses melalui satu IP saja, padahal kebanyakan sistem operasi sekarang dapat memperjanjikan lebih dari satu IP untuk setiap komputer dalam bentuk virtual IP. Penelitian ini mengkaji pemanfaatan virtual IP dari IP aliasing pada sistem operasi Linux sebagai Server Virtual IP untuk mikrokontroler. Prinsip dasar Server Virtual IP adalah pembuatan Virtual Host pada masing-masing IP untuk memproses paket-paket data dan menerjem...

Comparing genome-wide chromatin profiles using ChIP-chip or ChIP-seq

NARCIS (Netherlands)

Johannes, Frank; Wardenaar, Rene; Colomé Tatché, Maria; Mousson, Florence; de Graaf, Petra; Mokry, Michal; Guryev, Victor; Timmers, H. Th. Marc; Cuppen, Edwin; Jansen, Ritsert C.; Bateman, Alex

2010-01-01

Motivation: ChIP-chip and ChIP-seq technologies provide genomewide measurements of various types of chromatin marks at an unprecedented resolution. With ChIP samples collected from different tissue types and/ or individuals, we can now begin to characterize stochastic or systematic changes in

De reescrituras y obsesiones. La cicatriz y La voz de Mallick (1981, de Pedro Casariego Córdoba

Directory of Open Access Journals (Sweden)

Raúl Díaz Rosales

2012-01-01

Full Text Available En este trabajo se presenta una breve introducción a la recepción de la obra de Pedro Casariego Córdoba, así como a sus coordenadas estéticas, donde se establece su legado literario como una obsesión de ciertos elementos que vertebran su escritura. En el análisis del libro de poemas La voz de Mallick y la obra de teatro La cicatriz (de 1981 ambas, se constatará este hecho, al ser ambas creaciones dos visiones de un mismo tema: la liberación del condenado a través del amor. This paper focuses on the reception of Pedro Casariego Córdoba’s work, including his aesthetic coordinates, where he establishes his literary legacy as well as the obsession about some elements that build his writings. In the analysis of the poem La voz de Mallick and the play La cicatriz (both written in 1981, this fact will be proved, being these two creations visions of the same theme: the convicted’s liberation with the help of love.

Comparing genome-wide chromatin profiles using ChIP-chip or ChIP-seq

NARCIS (Netherlands)

Johannes, F.; Wardenaar, R.; Colome-Tatche, M.; Mousson, F.; de Graaf, P.; Mokry, M.; Guryev, V.; Timmers, H.T.; Cuppen, E.; Jansen, R.

2010-01-01

MOTIVATION: ChIP-chip and ChIP-seq technologies provide genome-wide measurements of various types of chromatin marks at an unprecedented resolution. With ChIP samples collected from different tissue types and/or individuals, we can now begin to characterize stochastic or systematic changes in

A FILOSOFIA DOS JOVENS SOBRE O SER JOVEM: UMA PESQUISA SOCIOPOÉTICA

Directory of Open Access Journals (Sweden)

Cristianne Teixeira Carneiro

2015-02-01

Full Text Available Objetivou-se conhecer os modos de pensar dos jovens de um curso técnico em enfermagem de um colégio técnico federal sobre “o que é ser jovem?”. A pesquisa se insere no paradigma qualitativo de investigação utilizando a Sociopoética, foi realizada com 11 jovens que cursavam o ensino médio concomitante ao técnico em enfermagem em 2013. Os jovens problematizaram a dimensão do tempo de espera para o mundo adulto, mostrando que não há um único modo de ser jovem e nem de se tornar adulto, pois para eles os ritos de passagem eram: casamento, saída da casa dos pais, o ingresso em um colégio técnico federal e o início dos estágios do curso técnico em enfermagem, demonstrando que esse momento não é fixo e nem demarcado. Eles também relataram jeitos de ser jovem em bandos que agem de modo diferente. Discutiram o tempo e a liberdade, ressaltando o quanto a rotina do jovem está relacionada à escola. Essa pesquisa possibilitou a oportunidade de reflexão sobre os conceitos sobre jovens, muitas vezes cristalizados numa sociedade que raramente leva em consideração a voz de quem mais entende sobre si mesmo, ou seja, do próprio sujeito que tem a experiência e vivencia a juventude.

Implementasi Sistem IP PBX menggunakan Briker

Directory of Open Access Journals (Sweden)

DWI ARYANTA

2017-06-01

Full Text Available Abstrak VoIP (Voice over Internet Protocol adalah komunikasi suara jarak jauh yang digunakan melalui jaringan IP. Pada penelitian ini dirancang sistem IP PBX dengan menggunakan teknologi berbasis VoIP. IP PBX adalah perangkat switching komunikasi telepon dan data berbasis teknologi Internet Protocol (IP yang mengendalikan ekstension telepon analog maupun ekstension IP Phone. Software VirtualBox digunakan dengan tujuan agar lebih memudahkan dalam sistem pengoperasian Linux yang dimana program untuk membuat IP PBX adalah menggunakan Briker yang bekerja pada Operating System Linux 2.6. Setelah proses penginstalan Briker pada Virtualbox dilakukan implementasi jaringan IP PBX. Setelah mengimplementasikan jaringan IP PBX sesuai dengan topologi, kemudian melakukan pengujian success call rate dan analisis Quality of Service (QoS. Pengukuran QoS menggunakan parameter jitter, delay, dan packet loss yang dihasilkan dalam sistem IP PBX ini. Nilai jitter sesama user Briker (baik pada smartphone maupun komputer mempunyai rata-rata berada pada nilai 16,77 ms. Sedangkan nilai packetloss yang didapat pada saat terdapat pada saat user 1 sebagai pemanggil telepon adalah 0%. Sedangkan persentase packet loss pada saat user 1 sebagai penerima telepon adalah 0,01%. Nilai delay pada saat berkomunikasi antar user berada pada 11,75 ms. Secara keseluruhan nilai yang didapatkan melalui penelitian ini, dimana hasil pengujian parameter-parameter QOS sesuai dengan standar yang telah direkomendasikan oleh ITU dan didapatkan nilai QoS dengan hasil “baik”. Kata Kunci : Briker, VoIP, QoS, IP PBX, Smartphone. Abstract VoIP (Voice over Internet Protocol is a long-distance voice communications over IP networks are used. In this study, IP PBX systems designed using VoIP -based technologies. IP PBX is a telephone switching device and data communication technology-based Internet Protocol (IP which controls the analog phone extensions and IP Phone extensions. VirtualBox software is

La educación física en la voz de los estudiantes de secundaria. Un estudio de caso

Directory of Open Access Journals (Sweden)

Didier Fernando Gaviria Cortes

2016-01-01

Full Text Available Tener en cuenta la voz del estudiante es relevante y útil en el proceso educativo, ya que integra la teo- ría y la práctica, da al estudiantado la oportunidad de participar en su propio aprendizaje y crea condiciones y posibilidades para que los estudiantes desarrollen o afiancen su propio sentido de ser. De allí que el objetivo principal del presente estudio fue identificar y analizar las creencias y percepciones de los estudiantes de secun- daria sobre la asignatura de educación física. La inves- tigación es cualitativa y su diseño es un estudio de caso en una institución educativa de Medellín-Colombia; se valoró su gusto por la asignatura, lo que aprenden en la clase y la importancia que le asignan. También fue incluido el proceso didáctico, la interacción y comporta- miento del profesorado. Las estrategias de recolección de información que se utilizaron fueron el cuestionario, la observación y el grupo focal. Los resultados muestran que el estudiantado construye una visión clásica sobre la clase de educación física: diversión, práctica, cambio de rutina respecto a otras asignaturas; e incluye aspectos relacionados con la salud y el aprendizaje de los depor- tes. Como conclusión, se encontró que uno de los mayo- res problemas a los que se enfrenta la educación física es la percepción del estudiantado, quienes reducen su participación en las clases a los componentes motrices, desconociendo la posibilidad de una educación física más humana, más integral.

In vitro synthesis and purification of PhIP-deoxyguanosine and PhIP-DNA oligomer covalent complexes

Energy Technology Data Exchange (ETDEWEB)

Freeman, J.

1994-12-01

2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) is a heterocyclic amine compound formed when meats are cooked at high temperatures. PhIP damages DNA by forming covalent complexes with DNA carcinogen. In an effort to understand how the binding of PhIP to DNA may cause cancer, it is important to characterize the structures of PhIP-damaged DNA molecules. Our HPLC data support fluorescence and {sup 32}P Post-labeling studies which indicate the formation of several species of 2{prime}deoxyguanosine-(dG) or oligodeoxynucleotide-PhIP adducts. The reaction of PhIP with dG resulted in a reddish precipitate that was likely the major adduct, N-(deoxyguanosin-8-yl)-PhIP (dG-C8-PhIP) adduct, with a more polar adduct fraction remaining in the supernatant. Reversed-phase HPLC analysis of the adducts in the supernatant revealed the existence of species of much shorter retention times than the dG-C8-PhIP adduct, confirming that these species are more polar than dG-C8-PhIP. At least four adducts were formed in the reaction of PhIP with DNA oligomer. HPLC analysis of the PhIP-DNA oligomer supernatant after butanol extractions revealed four unresolved peaks which spectra had maximum wavelengths between 340 and 360 nm. Though adduct peaks were not completely resolved, there was {approximately}3 minutes interval between the DNA oligomer peak and the adduct peaks. Furthermore, fluorescence emission data of the DNA oligomer-PhIP adduct solution show heterogeneous binding. The more polar PhIP adducts were fraction-collected and their structures will be solved by nuclear magnetic resonance or x-ray crystallography.

Ensuring Software IP Cleanliness

OpenAIRE

Mahshad Koohgoli; Richard Mayer

2007-01-01

At many points in the life of a software enterprise, determination of intellectual property (IP) cleanliness becomes critical. The value of an enterprise that develops and sells software may depend on how clean the software is from the IP perspective. This article examines various methods of ensuring software IP cleanliness and discusses some of the benefits and shortcomings of current solutions.

Gevaar VoIP voor telecomsector overdreven

NARCIS (Netherlands)

Deventer, M.O. van; Wegberg, M. van

2004-01-01

Het is een hype Voice-over-IP (VoIP) voor te stellen als een ontwrichtende technologie die de telecomindustrie ingrijpend zal veranderen. Maar hoe ontwrichtend is VoIP eigenlijk? Oskar van Deventer en Marc van Wegberg analyseren drie vormen van VoIP en laten zien dat alleen ‘VoIP-chat’ potentieel

Space Network IP Services (SNIS): An Architecture for Supporting Low Earth Orbiting IP Satellite Missions

Science.gov (United States)

Israel, David J.

2005-01-01

The NASA Space Network (SN) supports a variety of missions using the Tracking and Data Relay Satellite System (TDRSS), which includes ground stations in White Sands, New Mexico and Guam. A Space Network IP Services (SNIS) architecture is being developed to support future users with requirements for end-to-end Internet Protocol (IP) communications. This architecture will support all IP protocols, including Mobile IP, over TDRSS Single Access, Multiple Access, and Demand Access Radio Frequency (RF) links. This paper will describe this architecture and how it can enable Low Earth Orbiting IP satellite missions.

Ensuring Software IP Cleanliness

Directory of Open Access Journals (Sweden)

Mahshad Koohgoli

2007-12-01

Full Text Available At many points in the life of a software enterprise, determination of intellectual property (IP cleanliness becomes critical. The value of an enterprise that develops and sells software may depend on how clean the software is from the IP perspective. This article examines various methods of ensuring software IP cleanliness and discusses some of the benefits and shortcomings of current solutions.

Autoavaliação vocal e qualidade de vida em voz de indivíduos hipertensos Self-perception vocal and quality of life in the hypertensive individuals

Directory of Open Access Journals (Sweden)

Vanessa Veis Ribeiro

2013-02-01

Full Text Available OBJETIVO: obter dados de autoavaliação vocal e qualidade de vida em voz de indivíduos hipertensos MÉTODO: trata-se de estudo transversal, exploratório e descritivo. Participaram 84 indivíduos, 33 homens e 51 mulheres, de 54 a 87 anos (média de 68 anos que foram divididos em: Grupo Pesquisa (GP - 42 indivíduos portadores de hipertensão arterial e que recebiam tratamento medicamentoso específico para a doença há pelo menos um ano; Grupo Controle (GC: 42 indivíduos não hipertensos e com bom estado de saúde geral autorreferido. Todos os participantes responderam a um questionário composto por perguntas objetivas sobre autoavaliação vocal e ao protocolo Qualidade de Vida em Voz (QVV. RESULTADOS: não foram observadas diferenças quanto à autoavaliação vocal de indivíduos do GP e GC (p=0,075. Os escores médios totais obtidos no QVV também foram semelhantes entre os grupos (p=0,080. Houve diferença entre os grupos quanto à autopercepção do sintoma de "voz fraca", que teve maior ocorrência no GP (p=0,015. CONCLUSÃO: a utilização de medicamentos específicos para a hipertensão não promoveu diferenças na autoavaliação vocal e na qualidade de vida do grupo estudado, com exceção da percepção de "voz fraca". Indivíduos hipertensos e não hipertensos apresentaram escores abaixo do que se espera para sujeitos com vozes saudáveis e sem queixas vocais.PURPOSE: to get data of vocal self-assessment and voice quality of life in hypertensive individuals. METHOD: this is a cross-sectional, exploratory and descriptive study. There were 84 individuals ,33 men and 51 women, 54 to 87 years (68 years-old average who were divided into: Study Group (SG - 42 individuals with hypertension and receiving specific drug treatment for this disease for at least one year; Control Group (CG: 42 non-hypertensive individuals with good self-reported general health. All participants answered a questionnaire with questions about vocal self

Implementasi Protokol Keamanan TLS pada Aplikasi Layanan Komunikasi Suara Melalui Jaringan TCP/IP (VoIP)

OpenAIRE

Hariady, Ricky

2011-01-01

Saat ini layanan komunikasi suara melalui jaringan TCP/IP atau yang lebih dikenal dengan VoIP (Voice over IP) telah semakin banyak digunakan, namun teknologi VoIP yang ada saat ini masih rentan terhadap penyadapan ataupun pencurian data. Sementara protokol kriptografi TLS (Transport Layer Security) telah teruji dan banyak digunakan untuk mengamankan komunikasi melalui internet seperti pada layanan email dan web. Dengan mengimplementasikan protokol TLS pada sebuah aplikasi Vo...

Pessoa em Bethânia: os versos do desassossego na voz do encantamento

OpenAIRE

Barros, Andre Luiz Calsone

2013-01-01

Pessoa em Bethânia tem por tema a recriação dos versos de Caeiro no espetáculo Rosa dos Ventos O Show Encantado, tendo por intérprete Maria Bethânia. O corpus é o Poema VIII de Alberto Caeiro, heterônimo de Fernando Pessoa, da obra O Guardador de Rebanhos (1911 1912), transformado em roteiro dramáticomusical e tornado performance no espetáculo Rosa dos Ventos. Reinterpretado por meio da voz, do corpo, da música e dos mais variados recursos cênicos, o poema de Fernando ...

Voz del docente como herramienta principal de comunicación en el aula

OpenAIRE

Botella Quirant, María Teresa; Esteve-Faubel, José-María

2016-01-01

En todas las titulaciones cuyo uno de los campos laborales de los egresados es entre otros, dedicarse a la docencia, se observa la carencia dentro de los planes de estudio, de la más mínima formación en la herramienta principal que esos futuros profesionales docentes van a usar para enseñar: la voz. En cada grado de cada Facultad, hay un gran empeño en que domine los recursos técnicos de la materia correspondiente. Además, los egresados tienen que realizar un máster que les aproxime al mundo ...

Foundations of hardware IP protection

CERN Document Server

Torres, Lionel

2017-01-01

This book provides a comprehensive and up-to-date guide to the design of security-hardened, hardware intellectual property (IP). Readers will learn how IP can be threatened, as well as protected, by using means such as hardware obfuscation/camouflaging, watermarking, fingerprinting (PUF), functional locking, remote activation, hidden transmission of data, hardware Trojan detection, protection against hardware Trojan, use of secure element, ultra-lightweight cryptography, and digital rights management. This book serves as a single-source reference to design space exploration of hardware security and IP protection. · Provides readers with a comprehensive overview of hardware intellectual property (IP) security, describing threat models and presenting means of protection, from integrated circuit layout to digital rights management of IP; · Enables readers to transpose techniques fundamental to digital rights management (DRM) to the realm of hardware IP security; · Introduce designers to the concept of salutar...

Los servicios públicos domiciliarios en Colombia a la luz del modelo de Salida, voz y libertad de Albert Hirschman

Directory of Open Access Journals (Sweden)

Germán Valencia

2006-12-01

Full Text Available En la década de 1990 los servicios públicos domiciliarios en Colombia pasaron por una reforma importante: se permitió la entrada del sector privado y se le dio participación a los usuarios en la vigilancia y control de estos servicios. Pero, dada la dimensión colectiva y el carácter monopólico que tienen la mayoría de estos servicios, fue necesario introducir una serie de mecanismos institucionales que permitieran al usuario defender su bienestar. El artículo analiza, a través del modelo de Salida, voz y lealtad propuesto por Albert O. Hirschman, los desarrollos institucionales, mostrando los avances y carencias que tiene el sistema en este sentido. El trabajo enfatiza en la opción de Voz como la única defensa real que tienen los usuarios ante fallas en el sistema y presenta algunas propuestas de reformas.

Análise qualitativa do relato de mães com sintomatologia depressiva participantes do projeto Ipê

OpenAIRE

Marina Valente Guimarães Cecchini

2010-01-01

Este estudo faz parte do projeto temático Ipê; uma pesquisa longitudinal sobre depressão pós-parto (DPP), suas possíveis causas e conseqüências para a interação mãebebê e para o desenvolvimento infantil. As participantes do Ipê são atendidas pelo sistema único de saúde (SUS) da região do Butantã, em São Paulo, e foram entrevistadas em diversos momentos, inclusive no terceiro trimestre de gestação. As díades mãe-bebê foram avaliadas dois dias após o parto, no terceiro e no quarto mês de idade ...

Disfonias: relação S/Z e tipos de voz Dysphonias: S/Z ratio and types of voice

Directory of Open Access Journals (Sweden)

Carla Aparecida Cielo

2008-12-01

Full Text Available OBJETIVO: verificar o resultado da relação s/z e do tipo de voz em pacientes com diagnóstico de disfonias orgânico-funcionais (DOF e disfonias funcionais por uso incorreto da voz (DFUIV, bem como a ocorrência das diferentes patologias dentro das DOF. MÉTODOS: 70 indivíduos, de ambos os sexos, entre cinco e 65 anos de idade, atendidos numa clínica-escola, cadastrados em Banco de Dados, entre 1998 e 2006, com DOF e DFUIV, ambos classificados em três subgrupos: casos em que a relação s/z indicava hipercontração, normalidade, e falta de coaptação das pregas vocais durante a fonação. Os tipos de voz foram classificados conforme a ocorrência em: sem alteração; ruidosa; ruidosa, comprimida e/ou apresentando alteração de f0h; ruidosa e/ou apresentando alteração de f0h; e comprimida. RESULTADOS: ocorrência significativa de DOF e de DOF com nódulos vocais; nas DOF e DFUIV, ocorrência significante de relação s/z normal com tempos isolados de /s/ e /z/ abaixo do normal e voz ruidosa. CONCLUSÕES: O resultado da relação s/z foi estatisticamente significativo a favor da faixa de normalidade estabelecida, tanto nos pacientes com diagnóstico de DOF, quanto naqueles com DFUIV, sendo que, em ambos os grupos de pacientes, a voz ruidosa foi a mais freqüente. Dentro das DOF, os nódulos vocais foram significativamente mais freqüentes do que as demais patologias.PURPOSE: to check the result of s/z ratio and types of voice in patients with diagnosis of organic-functional dysphonias (DOF and functional dysphonias by incorrect use of voice (DFUIV, as well as the occurrence of the various pathologies within the DOF. METHODS: 70 subjects of both genders, between 5 and 65 years old, seen in a clinic-school, registered in a data bank from 1998 to 2006, with DOF and DFUIV, both classified in three sub-groups: cases in which the s/z ratio indicated hypercontraction, normality and lack of coaptation of the vocal folds during phonation

Producciones narrativo-visuales y voz de los y las estudiantes: indagación sobre los significados de participación en niños, niñas y jóvenes en escuelas municipales en Chile

Directory of Open Access Journals (Sweden)

Mauricio López Cruz

2015-11-01

Full Text Available La plena participación de los y las estudiantes es un aspecto clave de la inclusión educativa, y sin embargo, son pocos los estudios que aborden esta dimensión de la inclusión desde la perspectiva de los estudiantes. El presente artículo se propone indagar en los significados sobre participación en estudiantes de enseñanza básica y media de la Región Metropolitana de Chile, con el propósito de aportar elementos para una revisión crítica de las políticas de integración escolar e inclusión educativa. Se presentan dos estudios en los que se trabajó con construcción de narraciones visuales, utilizando fotoelicitación y fotografía participativa como estrategias metodológicas para explorar la voz de los y las estudiantes. Los resultados que se presentan se basan en el análisis de las categorías "aprender y colaborar con otros" y "espacios de inclusión y exclusión", las que representan los significados de mayor relevancia a partir de la indagación de tres dimensiones conceptuales: sentirse parte, ser escuchado y tomar decisiones. El espacio escolar no aparece como un espacio significativo en el que los estudiantes se sientan parte y la convivencia parece tensionada entre el compañerismo y el maltrato. Estos resultados subrayan la importancia de la participación como diálogo, colaboración y apoyo mutuo. URN: http://nbn-resolving.de/urn:nbn:de:0114-fqs160149

A performance da voz e a subjetividade na poesia contemporânea

Directory of Open Access Journals (Sweden)

Olliver Mariano Rosa e Goiandira Ortiz de Camargo

2013-10-01

Full Text Available http://dx.doi.org/10.5007/2176-8552.2013n15p205 Neste artigo, tratamos da relação que se estabelece entre o sujeito leitor e a subjetividade configurada no poema contemporâneo. Para isso, consideramos a performance vocal como instrumento de compreensão do texto poético, a despeito de hoje preponderar o uso do suporte impresso para sua publicação. Acreditamos que, na medida em que a feitura do poema implica a manipulação da materialidade sonora da palavra, a sua leitura precisa recorrer à escuta de uma voz, ainda que apenas como virtualidade. Constatamos, no entanto, que a realização vocal não dá a conhecer apenas o ritmo, o andamento e a entoação do verso; por meio dela, evidencia-se a presença da subjetividade que se manifesta na composição lírica. Nesse ponto, torna-se importante a observação de que a poesia abriga no mundo contemporâneo uma diversidade de configurações dadas por um sujeito criador múltiplo. Considerando isso, tomamos para estudo poemas de poetas contemporâneos, três portugueses, Fiama Hasse Pais Brandão, Ana Luísa Amaral e Manuel de Freitas, e três brasileiros, Francisco Alvim, Neide Archanjo e Claudia Roquette-Pinto. Com base na leitura desses poemas, propomos uma classificação das diferentes ocorrências do princípio subjetivo. Verificamos, por fim, de que forma a performance da voz entra em jogo com essas ocorrências. OBS: Olliver Mariano Rosa é bolsista do CNPq.

IPs

African Journals Online (AJOL)

Fr. Ikenga

special rights to the under-privileged IPs based on their culture, religion and .... and exploitation of natural resources, political determination and autonomy, .... supportive and sustaining.33Balancing individualism and communalism will avoid ...

An insight to the automatic categorization of speakers according to sex and its application to the detection of voice pathologies: A comparative study

Directory of Open Access Journals (Sweden)

Jorge Andrés Gómez-García

2016-01-01

Full Text Available Una categorización automática de los hablantes de acuerdo con su sexo mejora el rendimiento de un detector automático de patologías de voz. Esto se fundamenta en hallazgos que demuestran diferencias perceptuales, acústicas y anatómicas en voces masculinas y femeninas. En particular, este trabajo persigue dos objetivos: 1 diseñar un sistema que discrimine automáticamente el sexo de hablantes utilizando habla normofónica y patológica, 2 estudiar la influencia que este detector de sexo tiene sobre el acierto de un posterior detector de patologías de voz. La parametrización del detector automático de sexo se basa en MFCC aplicados sobre señales de voz; y MFCC aplicados a formas de onda glotal junto a parámetros que modelan el tracto vocal. Las formas de onda glotal se extraen de la voz a través de un filtrado inverso iterativo en celosía. En cuanto al detector de patologías, una parametrización MFCC se aplica a señales de voz. La clasificación, tanto en los detectores de sexo como de patología, se lleva a cabo con técnicas del estado del arte basadas en modelos de base universal. Experimentos son realizados sobre la base de datos Saarbrücken empleando la fonación sostenida de la vocal /a/. Los resultados indican que el sexo del hablante puede ser discriminado automáticamente utilizando habla normofónica y patológica, obteniendo una precisión de hasta un 95%. Por otra parte, al incluir información a priori sobre el sexo del hablante se produce una mejora de alrededor del 2% de rendimiento absoluto en EER, en tareas de detección de patología.

VoIP Accessibility: A Usability Study of Voice over Internet Protocol (VoIP) Systems and A Survey of VoIP Users with Vision Loss

Science.gov (United States)

Packer, Jaclyn; Reuschel, William

2018-01-01

Introduction: Accessibility of Voice over Internet Protocol (VoIP) systems was tested with a hands-on usability study and an online survey of VoIP users who are visually impaired. The survey examined the importance of common VoIP features, and both methods assessed difficulty in using those features. Methods: The usability test included four paid…

Offloading IP Flows onto Lambda-Connections

NARCIS (Netherlands)

Fioreze, Tiago; Oude Wolbers, Mattijs; van de Meent, R.; Pras, Aiko

2007-01-01

Optical networks are capable of switching IP traffic via lambda connections. In this way, big IP flows that overload the regular IP routing level may be moved to the optical level, where they get better Quality of Service (QoS). At the same time, the IP routing level is off-loaded and can serve

Mobile IP: Security & application

NARCIS (Netherlands)

Tuquerres, G.; Salvador, M.R.; Sprenkels, Ron

1999-01-01

As required in the TGS Mobile IP Advanced Module, this paper presents a survey of common security threats which mobile IP networks are exposed to as well as some proposed solutions to deal with such threats.

Voice over IP Security

CERN Document Server

Keromytis, Angelos D

2011-01-01

Voice over IP (VoIP) and Internet Multimedia Subsystem technologies (IMS) are rapidly being adopted by consumers, enterprises, governments and militaries. These technologies offer higher flexibility and more features than traditional telephony (PSTN) infrastructures, as well as the potential for lower cost through equipment consolidation and, for the consumer market, new business models. However, VoIP systems also represent a higher complexity in terms of architecture, protocols and implementation, with a corresponding increase in the potential for misuse. In this book, the authors examine the

Challenges Regarding IP Core Functional Reliability

Science.gov (United States)

Berg, Melanie D.; LaBel, Kenneth A.

2017-01-01

For many years, intellectual property (IP) cores have been incorporated into field programmable gate array (FPGA) and application specific integrated circuit (ASIC) design flows. However, the usage of large complex IP cores were limited within products that required a high level of reliability. This is no longer the case. IP core insertion has become mainstream including their use in highly reliable products. Due to limited visibility and control, challenges exist when using IP cores and subsequently compromise product reliability. We discuss challenges and suggest potential solutions to critical application IP insertion.

IP Infrastructure Geolocation

Science.gov (United States)

2015-03-01

by non-commercial enti- ties. HostiP is a community-driven geolocation service. It provides an Application Pro- gramming Interface ( API ) for...NAVAL POSTGRADUATE SCHOOL MONTEREY, CALIFORNIA THESIS IP INFRASTRUCTURE GEOLOCATION Thesis Advisor: Second Reader: by Guan Yan Cai March...FUNDING NUMBERS IP INFRASTRUCfURE GEOLOCATION N66001-2250-59231 6. AUTHOR(S) Guan Yan Cai 7. PERFORMING ORGANIZATION NAME(S) AND AOORESS(ES) 9

Mobile-ip Aeronautical Network Simulation Study

Science.gov (United States)

Ivancic, William D.; Tran, Diepchi T.

2001-01-01

NASA is interested in applying mobile Internet protocol (mobile-ip) technologies to its space and aeronautics programs. In particular, mobile-ip will play a major role in the Advanced Aeronautic Transportation Technology (AATT), the Weather Information Communication (WINCOMM), and the Small Aircraft Transportation System (SATS) aeronautics programs. This report presents the results of a simulation study of mobile-ip for an aeronautical network. The study was performed to determine the performance of the transmission control protocol (TCP) in a mobile-ip environment and to gain an understanding of how long delays, handoffs, and noisy channels affect mobile-ip performance.

Environmentální aspekty provozu vozů na CNG

OpenAIRE

Raiskup, Martin

2016-01-01

Tato bakalářská práce je zaměřená na téma environmentální aspekty provozu vozů na CNG. Nejprve je představen zemní plyn jako palivo pro spalovací motory. Jsou zhodnoceny jeho výhody a nevýhody. Dále jsou popsány jednotlivé spalovací systémy a komponenty motoru na stlačený zemní plyn. Hlavní část práce je zaměřená na ekologii. Je popsán vliv na životní prostředí u spalování stlačeného zemního plynu v porovnání s konvenčními palivy. Toto porovnání je provedeno také podle objektivnější Well to W...

Subtype-selective regulation of IP(3) receptors by thimerosal via cysteine residues within the IP(3)-binding core and suppressor domain.

Science.gov (United States)

Khan, Samir A; Rossi, Ana M; Riley, Andrew M; Potter, Barry V L; Taylor, Colin W

2013-04-15

IP(3)R (IP(3) [inositol 1,4,5-trisphosphate] receptors) and ryanodine receptors are the most widely expressed intracellular Ca(2+) channels and both are regulated by thiol reagents. In DT40 cells stably expressing single subtypes of mammalian IP(3)R, low concentrations of thimerosal (also known as thiomersal), which oxidizes thiols to form a thiomercurylethyl complex, increased the sensitivity of IP(3)-evoked Ca(2+) release via IP(3)R1 and IP(3)R2, but inhibited IP(3)R3. Activation of IP(3)R is initiated by IP(3) binding to the IBC (IP(3)-binding core; residues 224-604) and proceeds via re-arrangement of an interface between the IBC and SD (suppressor domain; residues 1-223). Thimerosal (100 μM) stimulated IP(3) binding to the isolated NT (N-terminal; residues 1-604) of IP(3)R1 and IP(3)R2, but not to that of IP(3)R3. Binding of a competitive antagonist (heparin) or partial agonist (dimeric-IP(3)) to NT1 was unaffected by thiomersal, suggesting that the effect of thimerosal is specifically related to IP(3)R activation. IP(3) binding to NT1 in which all cysteine residues were replaced by alanine was insensitive to thimerosal, so too were NT1 in which cysteine residues were replaced in either the SD or IBC. This demonstrates that thimerosal interacts directly with cysteine in both the SD and IBC. Chimaeric proteins in which the SD of the IP(3)R was replaced by the structurally related A domain of a ryanodine receptor were functional, but thimerosal inhibited both IP(3) binding to the chimaeric NT and IP(3)-evoked Ca(2+) release from the chimaeric IP(3)R. This is the first systematic analysis of the effects of a thiol reagent on each IP(3)R subtype. We conclude that thimerosal selectively sensitizes IP(3)R1 and IP(3)R2 to IP(3) by modifying cysteine residues within both the SD and IBC and thereby stabilizing an active conformation of the receptor.

Subtype-selective regulation of IP3 receptors by thimerosal via cysteine residues within the IP3-binding core and suppressor domain

Science.gov (United States)

Khan, Samir A.; Rossi, Ana M.; Riley, Andrew M.; Potter, Barry V. L.; Taylor, Colin W.

2013-01-01

IP3R (IP3 [inositol 1,4,5-trisphosphate] receptors) and ryanodine receptors are the most widely expressed intracellular Ca2+ channels and both are regulated by thiol reagents. In DT40 cells stably expressing single subtypes of mammalian IP3R, low concentrations of thimerosal (also known as thiomersal), which oxidizes thiols to form a thiomercurylethyl complex, increased the sensitivity of IP3-evoked Ca2+ release via IP3R1 and IP3R2, but inhibited IP3R3. Activation of IP3R is initiated by IP3 binding to the IBC (IP3-binding core; residues 224–604) and proceeds via re-arrangement of an interface between the IBC and SD (suppressor domain; residues 1–223). Thimerosal (100 μM) stimulated IP3 binding to the isolated NT (N-terminal; residues 1–604) of IP3R1 and IP3R2, but not to that of IP3R3. Binding of a competitive antagonist (heparin) or partial agonist (dimeric-IP3) to NT1 was unaffected by thiomersal, suggesting that the effect of thimerosal is specifically related to IP3R activation. IP3 binding to NT1 in which all cysteine residues were replaced by alanine was insensitive to thimerosal, so too were NT1 in which cysteine residues were replaced in either the SD or IBC. This demonstrates that thimerosal interacts directly with cysteine in both the SD and IBC. Chimaeric proteins in which the SD of the IP3R was replaced by the structurally related A domain of a ryanodine receptor were functional, but thimerosal inhibited both IP3 binding to the chimaeric NT and IP3-evoked Ca2+ release from the chimaeric IP3R. This is the first systematic analysis of the effects of a thiol reagent on each IP3R subtype. We conclude that thimerosal selectively sensitizes IP3R1 and IP3R2 to IP3 by modifying cysteine residues within both the SD and IBC and thereby stabilizing an active conformation of the receptor. PMID:23282150

Algo sobre ortografía de azoemia

Directory of Open Access Journals (Sweden)

Roberto Restrepo

1948-03-01

Full Text Available -Le faltó una h. Así exclamó un colega cuando en su presencia escribí azoemia y como nada cuesta dar la razón a los demás cuando otros están en su presencia (aunque luégo en privado se la quitemos, accedí a su corrección. Pero luégo, apartándome del corrillo, le pregunté: -¿ y por qué escribe usted azohemia? -Porque en su componente entra una palabra griega que significa sangre, que es la misma que entra en la voz hemorragia. -No colega -le contesté-o Esa creencia errada debe abandonarse. Aunque ciertamente la voz griega haima (sangre entra como componente en la voz azoemia, debe tenerse en cuenta que dicho componente no pide la h sino cuando es inicial, como hemorragia, hemofilia, hematemesis, etc., pero no en los demás casos. Así, usted escribe anemia, leucemia, toxemia, glicemia, etc.; y nadie ha tenido la ocurrencia de ponerles h. intermedia a estos vocablos. Pero si esta razón dejare alguna duda, téngase en cuenta que la e intermedia de azoemia no es la hai de hoima, sino la e de ázoe, y así tendremos que escribir azoe-mia, ya que a nadie se le ha ocurrido escribir aeohe para llamar al nitrógeno.

Applying a gaming approach to IP strategy.

Science.gov (United States)

Gasnier, Arnaud; Vandamme, Luc

2010-02-01

Adopting an appropriate IP strategy is an important but complex area, particularly in the pharmaceutical and biotechnology sectors, in which aspects such as regulatory submissions, high competitive activity, and public health and safety information requirements limit the amount of information that can be protected effectively through secrecy. As a result, and considering the existing time limits for patent protection, decisions on how to approach IP in these sectors must be made with knowledge of the options and consequences of IP positioning. Because of the specialized nature of IP, it is necessary to impart knowledge regarding the options and impact of IP to decision-makers, whether at the level of inventors, marketers or strategic business managers. This feature review provides some insight on IP strategy, with a focus on the use of a new 'gaming' approach for transferring the skills and understanding needed to make informed IP-related decisions; the game Patentopolis is discussed as an example of such an approach. Patentopolis involves interactive activities with IP-related business decisions, including the exploitation and enforcement of IP rights, and can be used to gain knowledge on the impact of adopting different IP strategies.

Vaccines and IP Rights: A Multifaceted Relationship.

Science.gov (United States)

Durell, Karen

2016-01-01

Just as there are many forms of vaccines and components to vaccines-particular compositions, delivery systems, components, and distribution networks-there are a variety of intellectual property (IP) protections applicable for vaccines. IP rights such as patent, copyright, trademarks, plant breeders' rights, and trade secrets may all be applicable to vaccines. Thus, discussion of IP rights and vaccines should not begin and end with the application of one IP right to a vaccine. The discussion should engage considerations of multiple IP rights applicable to a vaccine and how these can be utilized in an integrated manner in a strategy aimed at supporting the development and distribution of the vaccine. Such an approach to IP rights to vaccines allows for the integrated rights to be considered in light of the justifications for protecting vaccines with IP rights, as well as the issues relating to specific IP rights for vaccines, such as compulsory license regimes, available humanitarian purpose IP credits, etc. To view vaccines as the subject of multiple IP protections involves a refocusing, but the outcome can provide significant benefits for vaccine development and distribution.

Extending Tactical Fleet Communications Through VoIP

Science.gov (United States)

2014-09-01

corporate world , the military is leveraging VoIP communication solutions as well. Shore commands like Tactical Training Group Pacific use VoIP for...VoIP fuzzing (e.g., Asteroid , PROTOS, Sip-Proxy)  VoIP signaling manipulation (e.g., IAXAuthJack, IAXHangup, SIP-Kill)  VoIP media...as well, but instead of just matching the information to rules, it compares synchronization information between the protocols to determine if the

Hardware IP security and trust

CERN Document Server

Bhunia, Swarup; Tehranipoor, Mark

2017-01-01

This book provides an overview of current Intellectual Property (IP) based System-on-Chip (SoC) design methodology and highlights how security of IP can be compromised at various stages in the overall SoC design-fabrication-deployment cycle. Readers will gain a comprehensive understanding of the security vulnerabilities of different types of IPs. This book would enable readers to overcome these vulnerabilities through an efficient combination of proactive countermeasures and design-for-security solutions, as well as a wide variety of IP security and trust assessment and validation techniques. This book serves as a single-source of reference for system designers and practitioners for designing secure, reliable and trustworthy SoCs.

Presence in the IP multimedia subsystem

NARCIS (Netherlands)

Lin, L.; Liotta, A.

2007-01-01

With an ever increasing penetration of Internet Protocol (IP) technologies, the wireless industry is evolving the mobile core network towards all-IP network. The IP Multimedia Subsystem (IMS) is a standardised Next Generation Network (NGN) architectural framework defined by the 3rd Generation

Performance of VoIP on HSDPA

DEFF Research Database (Denmark)

Wang, Bang; Pedersen, Klaus I.; Kolding, Troels E.

2005-01-01

This paper provides packet scheduler design and performance simulations for running VoIP services over high-speed downlink packet access (HSDPA) in WCDMA. The main challenge of supporting VoIP service on HSDPA is the tight delay requirement combined with the small VoIP packet size. A packet...... scheduler design incorporating VoIP packet aggregation and user multiplexing is proposed and the VoIP capacity is studied for a macro-cellular environment. Results are obtained for different delay budgets and packet scheduling settings, using either blind round robin or a slightly modified version...... of proportional fair scheduling. For proportional fair scheduling with code-multiplexing of 4-users, the downlink VoIP cell capacity on HSDPA is found to be in the range 72-104 users depending on whether the delay budget for the Node-B scheduling and user reception equals 80 ms or 150 ms, respectively....

Coralistas amadores: auto-imagem, dificuldades e sintomas na voz cantada Amateur choir singers: self-image, difficulties and symptoms of the singing voice

Directory of Open Access Journals (Sweden)

Ana Cristina de Castro Coelho

2013-04-01

Full Text Available OBJETIVO: conhecer a auto-imagem, dificuldades e presença de sintomas negativos após o canto em coralistas amadores com diferentes classificações vocais, idades e experiência. MÉTODO: cento e vinte e cinco cantores responderam a um questionário que abordou dados de identificação, informações sobre a auto-imagem da voz cantada, dificuldades apresentadas no canto e ocorrência ou não de sintomas vocais após o canto. RESULTADOS: a comparação por naipes evidenciou maior dificuldade na emissão de sons agudos para os contraltos e baixos, maior dificuldade na emissão graves para os sopranos, maior dificuldade na transição de registro grave para agudo para os baixos, e maior cansaço vocal para os contraltos. Na divisão por idade, tanto adultos jovens e adultos referiram maior soprosidade do que os idosos. Os adultos referiram melhor intensidade vocal do que adultos jovens. Os adultos jovens consideraram seu timbre de voz adequado mais frequentemente do que adultos. Em relação à experiência, os cantores menos experientes referiram percepção de voz rouca em maior número do que os cantores mais experientes, que referiram apresentar intensidade adequada durante o canto em maior número do que os demais. Cantores menos experientes referiram maior ocorrência de rouquidão após o canto do que cantores mais experientes. CONCLUSÃO: as dificuldades encontradas no canto estão atreladas ao naipe, e não dependem da idade e nem da experiência. Sintomas estão relacionados ao naipe e ao grau de experiência com o canto. A auto-imagem vocal negativa também está relacionada ao naipe e ao nível de experiência, sendo que a auto-imagem positiva é mais comum em cantores experientes.PURPOSE: to evaluate vocal self-perception, difficulties and presence of negative symptoms after singing of amateur choir singers of different vocal classifications, age and experience. METHOD: one hundred and twenty five singers answered a questionnaire

Measuring the impostor phenomenon: a comparison of Clance's IP Scale and Harvey's I-P Scale.

Science.gov (United States)

Holmes, S W; Kertay, L; Adamson, L B; Holland, C L; Clance, P R

1993-02-01

Many of the discrepancies reported to date in empirical investigations of the impostor phenomenon (IP) may be due in part to (a) the use of different methods for identifying individuals suffering from this syndrome (impostors), (b) the common use of a median split procedure to classify subjects and (c) the fact that subjects in many studies were drawn from impostor-prone samples. In this study, we compared the scores of independently identified impostors and nonimpostors on two instruments designed to measure the IP: Harvey's I-P Scale and Clance's IP Scale. The results suggest that Clance's scale may be the more sensitive and reliable instrument. Cutoff score suggestions for both instruments are offered.

A comparison of the microstructure and properties of the IPS Empress 2 and the IPS Empress glass-ceramics.

Science.gov (United States)

Höland, W; Schweiger, M; Frank, M; Rheinberger, V

2000-01-01

The aim of this report is to analyze the microstructures of glass-ceramics of the IPS Empress 2 and IPS Empress systems by scanning electron microscopy. The main properties of the glass-ceramics were determined and compared to each other. The flexural strength of the pressed glass-ceramic (core material) was improved by a factor of more than three for IPS Empress 2 (lithium disilicate glass-ceramic) in comparison with IPS Empress (leucite glass-ceramic). For the fracture toughness, the K(IC) value was measured as 3.3 +/- 0.3 MPa. m(0.5) for IPS Empress 2 and 1.3 +/- 0.1 MPa. m(0.5) for IPS Empress. Abrasion behavior, chemical durability, and optical properties such as translucency of all glass-ceramics fulfill the dental standards. The authors concluded that IPS Empress 2 can be used to fabricate 3-unit bridges up to the second premolar. Copyright 2000 John Wiley & Sons, Inc.

ChIP-PIT: Enhancing the Analysis of ChIP-Seq Data Using Convex-Relaxed Pair-Wise Interaction Tensor Decomposition.

Science.gov (United States)

Zhu, Lin; Guo, Wei-Li; Deng, Su-Ping; Huang, De-Shuang

2016-01-01

In recent years, thanks to the efforts of individual scientists and research consortiums, a huge amount of chromatin immunoprecipitation followed by high-throughput sequencing (ChIP-seq) experimental data have been accumulated. Instead of investigating them independently, several recent studies have convincingly demonstrated that a wealth of scientific insights can be gained by integrative analysis of these ChIP-seq data. However, when used for the purpose of integrative analysis, a serious drawback of current ChIP-seq technique is that it is still expensive and time-consuming to generate ChIP-seq datasets of high standard. Most researchers are therefore unable to obtain complete ChIP-seq data for several TFs in a wide variety of cell lines, which considerably limits the understanding of transcriptional regulation pattern. In this paper, we propose a novel method called ChIP-PIT to overcome the aforementioned limitation. In ChIP-PIT, ChIP-seq data corresponding to a diverse collection of cell types, TFs and genes are fused together using the three-mode pair-wise interaction tensor (PIT) model, and the prediction of unperformed ChIP-seq experimental results is formulated as a tensor completion problem. Computationally, we propose efficient first-order method based on extensions of coordinate descent method to learn the optimal solution of ChIP-PIT, which makes it particularly suitable for the analysis of massive scale ChIP-seq data. Experimental evaluation the ENCODE data illustrate the usefulness of the proposed model.

Outbreak of Ips nitidus and Ips shangrila in northeastern margin of the Tibetan Plateau

Czech Academy of Sciences Publication Activity Database

Jakuš, R.; Kalinová, Blanka; Hoskovec, Michal; Knížek, M.; Schlyter, F.; Sun, J.-H.; Zhang, Q. H.

2011-01-01

Roč. 89, - (2011), s. 111-117 ISSN 1436-1566 R&D Projects: GA MŠk ME 860 Institutional research plan: CEZ:AV0Z40550506 Keywords : Ips shangrila * Ips nitidus * pheromone s * GCxGC-TOFMS Subject RIV: CC - Organic Chemistry

Voice over IP in Wireless Heterogeneous Networks

DEFF Research Database (Denmark)

Fathi, Hanane; Chakraborty, Shyam; Prasad, Ramjee

with the deployment of wireless heterogeneous systems, both speech and data traffic are carrried over wireless links by the same IP-based packet-switched infrastructure. However, this combination faces some challenges due to the inherent properties of the wireless network. The requirements for good quality VoIP...... communications are difficult to achieve in a time-varying environment due to channel errors and traffic congestion and across different systems. The provision of VoIP in wireless heterogeneous networks requires a set of time-efficient control mechanisms to support a VoIP session with acceptable quality....... The focus of Voice over IP in Wierless Heterogeneous Networks is on mechanisms that affect the VoIP user satisfaction  while not explicitly involved in the media session. This relates to the extra delays introduced by the security and the signaling protocols used to set up an authorized VoIP session...

Chromatin immunoprecipitation (ChIP) of plant transcription factors followed by sequencing (ChIP-SEQ) or hybridization to whole genome arrays (ChIP-CHIP)

NARCIS (Netherlands)

Kaufmann, K.; Muiño, J.M.; Østerås, M.; Farinelli, L.; Krajewski, P.; Angenent, G.C.

2010-01-01

Chromatin immunoprecipitation (ChIP) is a powerful technique to study interactions between transcription factors (TFs) and DNA in vivo. For genome-wide de novo discovery of TF-binding sites, the DNA that is obtained in ChIP experiments needs to be processed for sequence identification. The sequences

77 FR 33227 - Assessment Questionnaire-IP Sector Specific Agency Risk Self Assessment Tool (IP-SSARSAT)

Science.gov (United States)

2012-06-05

... DEPARTMENT OF HOMELAND SECURITY [Docket No. DHS-2011-0069] Assessment Questionnaire--IP Sector... comments concerning new Information Collection Request--Assessment Questionnaire--IP Sector Specific Agency... http://www.regulations.gov , including any personal information provided. OMB is particularly...

Inositol hexakisphosphate (IP6) generated by IP5K mediates cullin-COP9 signalosome interactions and CRL function.

Science.gov (United States)

Scherer, Paul C; Ding, Yan; Liu, Zhiqing; Xu, Jing; Mao, Haibin; Barrow, James C; Wei, Ning; Zheng, Ning; Snyder, Solomon H; Rao, Feng

2016-03-29

The family of cullin-RING E3 Ligases (CRLs) and the constitutive photomorphogenesis 9 (COP9) signalosome (CSN) form dynamic complexes that mediate ubiquitylation of 20% of the proteome, yet regulation of their assembly/disassembly remains poorly understood. Inositol polyphosphates are highly conserved signaling molecules implicated in diverse cellular processes. We now report that inositol hexakisphosphate (IP6) is a major physiologic determinant of the CRL-CSN interface, which includes a hitherto unidentified electrostatic interaction between the N-terminal acidic tail of CSN subunit 2 (CSN2) and a conserved basic canyon on cullins. IP6, with an EC50 of 20 nM, acts as an intermolecular "glue," increasing cullin-CSN2 binding affinity by 30-fold, thereby promoting assembly of the inactive CRL-CSN complexes. The IP6 synthase, Ins(1,3,4,5,6)P5 2-kinase (IPPK/IP5K) binds to cullins. Depleting IP5K increases the percentage of neddylated, active Cul1 and Cul4A, and decreases levels of the Cul1/4A substrates p27 and p21. Besides dysregulating CRL-mediated cell proliferation and UV-induced apoptosis, IP5K depletion potentiates by 28-fold the cytotoxic effect of the neddylation inhibitor MLN4924. Thus, IP5K and IP6 are evolutionarily conserved components of the CRL-CSN system and are potential targets for cancer therapy in conjunction with MLN4924.

IP Security für Linux

OpenAIRE

Parthey, Mirko

2001-01-01

Die Nutzung des Internet für sicherheitskritische Anwendungen erfordert kryptographische Schutzmechanismen. IP Security (IPsec) definiert dafür geeignete Protokolle. Diese Arbeit gibt einen Überblick über IPsec. Eine IPsec-Implementierung für Linux (FreeS/WAN) wird auf Erweiterbarkeit und Praxistauglichkeit untersucht. Using the Internet in security-critical areas requires cryptographic protection, for which IP Security (IPsec) defines suitable protocols. This paper gives an overview of IP...

La débil Europa: consideraciones críticas sobre la política exterior de la Unión

Directory of Open Access Journals (Sweden)

Víctor C. Pascual Planchuelo

2009-07-01

Full Text Available Este trabajo tiene como objetivo analizar la Política Exterior de la Unión Europea. Para ello se revisa la orientación general de todos los países miembros, sus agendas diplomáticas y posturas geoestratégicas. En un contexto global en el que la Unión Europea desempeña un rol de simple observador, sin posibilidad de ejercer un poder decisorio sobre los aspectos fundamentales de la política internacional, la única opción válida es la de reforzar la Política Exterior. La Unión Europea tiene la obligación de hablar ante el mundo con una sola voz, y no delegar los temas de defensa y seguridad al aliado de costumbre, los Estados Unidos.

REFLEXIÓN SOBRE LA DIGNIDAD DEL NIÑO Y NIÑA

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Esperanza Del Niño Jesús Cabrera Díaz

2017-12-01

Full Text Available El presente artículo de reflexión es producto de la revisión de la tesis de grado del doctorado titulada “dilemas Bioéticos en las prácticas discursivas de psicoterapeutas que atienden el maltrato infantil”, y realiza una deliberación sobre la dignidad de niños y niñas. Parte de los conceptos de dignidad propios de Grecia y Roma, donde la dignidad es propia del varón por origen aristocrático, o dada por el desempeño en un cargo público. En este ambiente, el concepto de dignidad es impensable para los niños y niñas. Este concepto surge simultáneamente con el de pater familiae, en el mismo contexto. Para el pater familiae, el niño o niña es un objeto-propiedad del adulto, sin reconocimiento como ser humano con dignidad y respeto. Es un niño o niña subordinado al adulto, sin voz, sin posibilidad alguna de tomar decisiones o de ser considerado un ser humano. Este acervo cultural sobre dignidad y de niño o niña, históricamente permea la cultura occidental y llega hasta nuestros días. Por lo anterior, se plantea la necesidad de reflexionar sobre la dignidad del niño o niña, transformar la cultura para que el niño o niña sea considerado un ser digno, perteneciente a la especie humana, con igual dignidad a la del adulto. Desde la Bioética, este cambio conceptual sobre lo que es un niño o niña, lleva a la expresión cotidiana de valorar, respetar, dignificar al niño o niña, a través de la escucha, el diálogo, el consenso, el acuerdo, la participación activa en toda decisión que le compete.

PEMBELAJARAN IPS DALAM REALITA DI ERA KTSP: STUDI EKSPLORASI PELAKSANAAN PEMBELAJARAN IPS PADA JENJANG SMP DI KABUPATEN PATI

Directory of Open Access Journals (Sweden)

Edi Sutrisna

2011-10-01

Full Text Available Application of KTSP as a curriculum based on competency requires the implementation of strategies and methods that can deliver a number of learners achieving a particular competence. IPS as a subject who has a noble purpose, namely to prepare students to be good citizens, should be taught to students through appropriate strategies and methods by utilizing various media sources and learning. Most social studies teachers still promote the use of expository strategies in presenting lessons of Social Science education and the use of resources and learning media are minimal. Environment, as a laboratory of IPS is not utilized properly.The study shows that most teachers still tend to use expository teaching strategies, use of resources and learning media that are less varied, and integrated approaches to teaching social studies can not be realized by the teachers due to various constraints.   Keywords: learning, IPS, junior school, KTSP   Penerapan KTSP sebagai kurikulum berbasis kompetensi membutuhkan penerapan strategi dan metode yang dapat memberikan sejumlah peserta didik mencapai kompetensi tertentu. IPS sebagai subjek yang memiliki tujuan mulia, yaitu untuk mempersiapkan siswa untuk menjadi warga negara yang baik, harus diajarkan kepada siswa melalui strategi yang tepat dan metode dengan memanfaatkan berbagai sumber media dan pembelajaran. Kebanyakan guru IPS masih menggunakan strategi ekspositori dalam menyajikan meteri pelajaran IPS dengan menggunakan sumber daya dan media pembelajaran yang minimal. Lingkungan sekitar, sebagai laboratorium IPS tidak digunakan menunjukkan pembelajaran yang baik. Kebanyakan guru masih cenderung untuk menggunakan strategi pengajaran ekspositori, penggunaan sumber daya dan media pembelajaran yang kurang bervariasi, dan pendekatan terpadu untuk mengajar IPS, sehingga tidak dapat direalisasikan oleh para guru karena berbagai kendala.   Kata kunci: pembelajaran, IPS, SMP, KTSP  

CORRELAÇÃO ENTRE PUBLICAÇÕES CIENTÍFICAS E PATENTES COM CÉLULAS-TRONCO PLURIPOTENTE INDUZIDAS (iPS: BASES PARA UMA PROSPECÇÃO TECNOLÓGICA

Directory of Open Access Journals (Sweden)

Maria Acelina Carvalho

2014-12-01

Full Text Available A reprogramação de células somáticas para uma célula pluripotente indiferenciada, com características de uma célula-tronco embrionária (CTE, é um dos avanços promissores no campo da biologia celular na última década. O objetivo desse trabalho foi reunir informações como base de uma prospecção tecnológica prévia sobre o tema células-tronco pluripotente induzidas (iPS e verificar se existe correlação entre o número de publicações científicas e número de patentes na referida área. Foram pesquisadas patentes depositadas no EPO, USPTO e INPI e publicações científicas na base de dados Web of Science com a finalidade de realizar a correlação entre a quantidade de publicações científicas e o número de patentes depositados por ano e por países .A Organização Mundial de Propriedade Intelectual (WO seguida dos Estados Unidos e China detém os maiores números de patentes depositadas envolvendo iPS. Observa-se que as patentes envolvendo iPS aparecem a partir de 2007 com uma única patente japonesa registrada no INPI. Os EUA lidera o número de publicações científicas sobre iPS com 1.679 publicações na base de dados Web of Science.

Analysis of Handoff Mechanisms in Mobile IP

Science.gov (United States)

Jayaraj, Maria Nadine Simonel; Issac, Biju; Haldar, Manas Kumar

2011-06-01

One of the most important challenges in mobile Internet Protocol (IP) is to provide service for a mobile node to maintain its connectivity to network when it moves from one domain to another. IP is responsible for routing packets across network. The first major version of IP is the Internet Protocol version 4 (IPv4). It is one of the dominant protocols relevant to wireless network. Later a newer version of IP called the IPv6 was proposed. Mobile IPv6 is mainly introduced for the purpose of mobility. Mobility management enables network to locate roaming nodes in order to deliver packets and maintain connections with them when moving into new domains. Handoff occurs when a mobile node moves from one network to another. It is a key factor of mobility because a mobile node can trigger several handoffs during a session. This paper briefly explains on mobile IP and its handoff issues, along with the drawbacks of mobile IP.

Direct reduction of N-acetoxy-PhIP by tea polyphenols: a possible mechanism for chemoprevention against PhIP-DNA adduct formation

International Nuclear Information System (INIS)

Lin Dongxin; Thompson, Patricia A.; Teitel, Candee; Chen Junshi; Kadlubar, Fred F.

2003-01-01

The chemopreventive effect of tea against 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)-DNA adduct formation and its mechanism were studied. Rats were exposed to freshly prepared aqueous extracts of green tea (3% (w/v)) as the sole source of drinking water for 10 days prior to administration with a single dose of PhIP (10 mg/kg body weight) by oral gavage. PhIP-DNA adducts in the liver, colon, heart, and lung were measured using the 32 P-postlabelling technique. Rats pre-treated with tea and given PhIP 20 h before sacrifice had significantly reduced levels of PhIP-DNA adducts as compared with controls given PhIP alone. The possible mechanism of protective effect of tea on PhIP-DNA adduct formation was then examined in vitro. It was found that an aqueous extract of green and black tea, mixtures of green and black tea polyphenols, as well as purified polyphenols could strongly inhibit the DNA binding of N-acetoxy-PhIP, a putative ultimate carcinogen of PhIP formed in vivo via metabolic activation. Among these, epigallocatechin gallate was exceptionally potent. HPLC analyses of these incubation mixtures containing N-acetoxy-PhIP and the tea polyphenols each revealed the production of the parent amine, PhIP, indicating the involvement of a redox mechanism. In view of the presence of relatively high levels of tea polyphenols in rat and human plasma after ingestion of tea, this study suggests that direct reduction of the ultimate carcinogen N-acetoxy-PhIP by tea polyphenols is likely to be involved in the mechanism of chemoprotection of tea against this carcinogen

A voz dos cientistas críticos

Directory of Open Access Journals (Sweden)

Lewgoy Flavio

2000-01-01

Full Text Available A polêmica sobre os organismos geneticamente modificados (OGMs é complexa, envolvendo poderosos interesses econômicos, bem como aspectos éticos, legais, emocionais e científicos. Os últimos são abordados neste artigo. Os cientistas do grupo `triunfalista' afirmam que os OGMs e produtos derivados são seguros para o meio ambiente e não oferecem maiores riscos à saúde que os similares não modificados geneticamente. Isto é contestado pelos cientistas `críticos', motivados pela escassez de estudos sobre impactos ambientais e toxicidade dos OGMs, e que apontam falhas em testes efetuados pelas empresas donas das patentes dos transgênicos. Questionam, ainda, o estado atual do processo de transgenia, pouco preciso, o que, aliado ao desconhecimento das funções de 97% do genoma, pode acarretar efeitos imprevistos, com riscos ainda não avaliados sobre o meio ambiente e a saúde pública, por exemplo, a transferência de genes alienígenas para outras espécies, o surgimento de toxinas, a criação de novos vírus, o impacto sobre insetos benéficos e a biodiversidade, em geral. Já há exemplos desses efeitos.

IP3 levels and their modulation FY fusicoccin measured by a novel [3H] IP3 binding assay

International Nuclear Information System (INIS)

Aducci, P.; Marra, M.

1990-01-01

A recently developed sensitive assay based on the binding reaction of IP3 to bovine adrenal preparations has been utilized for determining the level of endogenous inositol-1,4,5 trisphosphate (IP3) in maize roots and coleoptiles. The amount of IP3 found in these tissues ranges from 0.1 to 1.0 nmol g-1 fresh weight. Reproducible results were obtained with extracts of tissues from a same harvest, while they showed a 2-3 fold variation when different batches of plantlets were compared. The fungal phytotoxin fusicoccin (FC) known to affect several physiological processes in higher plants, increases the level of IP3 in coleoptiles. This observation suggests that IP3 might be involved in the transduction of the FC encoded signal from its receptors at the plasmalemma level to the cell machinery

Controle Social: a dinâmica da Teoria da Saída, Voz e Lealdade no Contexto da Administração Pública Brasileira (Social Control: The Dynamics of theTheory of Output, voice and Loyalty in the Contexto of the Brazilian Public Administration

Directory of Open Access Journals (Sweden)

Fernanda Rodrigues da Silva

2017-10-01

Full Text Available Resumo: Em linhas gerais este artigo objetivou desenvolver uma sistematização conceitual das diferentes contribuições científicas disponíveis sobre “Controle Social”. De modo específico este estudo propôs-se a trazer para o debate da Administração Pública leituras diferenciadas que dialogam com a dinâmica da teoria da Saída, Voz e Lealdade defendida por Hirschman (1973 vivenciada no contexto brasileiro do Controle Social. Com base nos resultados das concepções teóricas aferidas percebe-se que, quando diante das decisões políticas a serem tomadas o Estado ou mesmo a sociedade tornam-se indiferentes, há a predominância do mecanismo da Saída. Quando ocorre o inverso, ou seja, a participação nas decisões políticas, na esfera pública, exercita-se o mecanismo da Voz, nesta pesquisa, denominado como Gestão Social. E quando o Estado exerce uma boa governança e a sociedade desempenha a cidadania crítica e consciente, a Lealdade entra em cena no sistema democrática do país e, consequentemente, efetiva-se o Controle Social. Palavras-chave: Saída. Voz. Lealdade.Abstract: In general, this research aimed to develop a conceptual systematization of the different scientific contributions available on “Social Control”. Specifically, this study aimed to bring to the Public Administration debate differentiated readings that dialogue with the dynamics of the theory of Output, Voice and Loyalty defended by Hirschman (1973 experienced in the Brazilian context of Social Control. According to the results of the theoretical conceptions, it is possible to realize that when the political decisions to be taken the State or even society become indifferent, there is a predominance of the mechanism of Output. When the reverse occurs, that is, participation in political decisions, in the public sphere, the Voice mechanism is exercised, in this research, called Social Management. And when the State exercises good governance and the society

No queremos una sola voz

Directory of Open Access Journals (Sweden)

Lourdes Barrezueta

2015-01-01

Full Text Available Comunicación y Género, acopia trabajos que vinculan a la mujer y la comunicación y sus esfuerzos por no ser consideradas inferiores. Del libro a la pantalla, acerca a algunas reflexiones sobre el proceso que lleva del libro a la pantalla por la polémica que despierta la adaptación de las novelas, puesto que muchos señalan que la trama se ve desfigurada. Se agregan varios temas sobre el cine. En "Días de Radio", se plantea el que a pesar de la censura y los problemas económicos que deben enfrentar, las radios populares de América Latina, siguen ganando espacios, de su desarrollo depende una mayor profundización de la democracia. Tema de debate es Estrategias comunicativas en Chiapas y Haití. Se añaden dos entrevistas a un caricaturista brasileño y a un corresponsal de guerra muy prestigiado.

Intellectual Property and Strategic Agreements (IP/SA) | FNLCR

Science.gov (United States)

What does IP/SA handle? IP/SA handles all invention issues including patents and copyrights. All employee inventionreports are filed through the IP/SA office for all activities under the OTS contract.Additionally,&nbs

Opportunities for IP  in Communications Beyond 3G

DEFF Research Database (Denmark)

Nielsen, Thomas Toftegaard; Jacobsen, Rune H.

2005-01-01

Future communication will be based on TCP/IP as common network and transport layers to provide global connectivity to users and applications. IP is used to provide ubiquitous access across different access networks and exploits the benefits of a common connectivity layer while reducing the cost...... of operation and maintenance of the network. This paper discusses the opportunities for IP in the evolution towards a future broadband, all-IP mobile communication network. In particular, we argue for three opportunities for the future: Interworking access technologies over IP, IP layer transparency...

Sobre el héroe geminado en Tolstói y Cervantes

Directory of Open Access Journals (Sweden)

Olga Svetlakova

2016-01-01

Full Text Available A partir del concepto de Bajtín de cronotopo, este trabajo se propone distinguir un dibujo cronotópico particular en la imagen geminada de Pierre/Andréi en Guerra y paz de Tolstói, comparándola con el héroe geminado Sancho/don Quijote de Cervantes. En Pierre y Andréi, así como en don Quijote y Sancho, se correlaciona y se contrapone la voz de todo el ser, que supera por mucho lo humano y lo individual, y también la voz del “yo” singular, distanciado en su pensamiento trágico.

Mobile IP

NARCIS (Netherlands)

Heijenk, Geert; Sallent, S.; Pras, Aiko

1999-01-01

The Internet is growing exponentially, both in the amount of traffic carried, and in the amount of hosts connected. IP technology is becoming more and more important, in company networks (Intranets), and also in the core networks for the next generation mobile networks. Further, wireless access to

Migración de redes de voz IPv4 a IPv6

Directory of Open Access Journals (Sweden)

Octavio Salcedo

2012-03-01

Full Text Available This article discusses the current state of voice networks and IP networks running on version 6, and the different architectures that can be implemented. The results analyze the benefits of voice over IP networks with version 6 over version 4 and its influence on the quality of service, from measuring and evaluating outstanding parametersdelay, jitter and packet loss.

SISTEMAS MULTIMEDIA BASADOS EN PROTOCOLO IP IMS APLICADOS A SERVICIOS LTE DE 4G

Directory of Open Access Journals (Sweden)

Edgar Alfonso Cipagauta Pedraza

2013-01-01

Full Text Available Este artículo presenta de una manera sencilla, el sistema creado para soportar los servicios de multimedia dentro de red de nueva generación (NGN llamada IP Multimedia Subsystem (IMS a la vez que se explica su relación con la tecnología Long Term Evolution (LTE definida por el 3GPP en su release 8. IMS se trata de una arquitectura integrada en el núcleo de red para ofrecer servicios multimediales de audio y video sobre una infraestructura. Entonces ahora, los servicios prestados pasarán a ser ofrecidos a través de IP IMS y será la piedra angular en donde estos servicios se generarán y se ofrecerán. LTE es sin duda un impulsor de IMS, pero hay otros factores que empiezan a favorecer y a plantear un modelo de negocio favorable para la arquitectura multimedia. IMS está orientado a habilitar la convergencia de servicios, combinando el crecimiento de la Internet con el de las comunicaciones móviles, desde cualquier ubicación y método de forma continua y permanente.

Continuously Connected With Mobile IP

Science.gov (United States)

2002-01-01

Cisco Systems developed Cisco Mobile Networks, making IP devices mobile. With this innovation, a Cisco router and its connected IP devices can roam across network boundaries and connection types. Because a mobile user is able to keep the same IP address while roaming, a live IP connection can be maintained without interruption. Glenn Research Center jointly tested the technology with Cisco, and is working to use it on low-earth-orbiting research craft. With Cisco's Mobile Networks functionality now available in Cisco IOS Software release 12.2(4)T, the commercial advantages and benefits are numerous. The technology can be applied to public safety, military/homeland security, emergency management services, railroad and shipping systems, and the automotive industry. It will allow ambulances, police, firemen, and the U.S. Coast Guard to stay connected to their networks while on the move. In the wireless battlefield, the technology will provide rapid infrastructure deployment for U.S. national defense. Airline, train, and cruise passengers utilizing Cisco Mobile Networks can fly all around the world with a continuous Internet connection. Cisco IOS(R) Software is a registered trademark of Cisco Systems.

Análisis comparativo de distintas toolkits para el reconocimiento biométrico de personas mediante voz

OpenAIRE

Ruíz, Silvia; Miranda, Ernesto; Herlein, Mauro; Etchart, Graciela; Alvez, Carlos E.

2017-01-01

El objetivo de este trabajo es realizar un análisis comparativo de distintas toolkits para el reconocimiento biométrico de personas mediante voz. Hoy en día los sistemas de identificación de personas se han convertido en una necesidad para la sociedad. A medida que avanza la tecnología y la aplicación de la misma en entornos tanto de ocio como de seguridad, la evolución en desarrollo biométrico es muy grande. Los sistemas de identificación o verificación tradicionales (tarjetas o claves) se h...

75 FR 13235 - IP-Enabled Services

Science.gov (United States)

2010-03-19

... FEDERAL COMMUNICATIONS COMMISSION 47 CFR Part 63 [WC Docket No. 04-36; FCC 09-40] IP-Enabled Services AGENCY: Federal Communications Commission ACTION: Final rule; announcement of effective date... Internet Protocol (VoIP) service the discontinuance obligations that apply to domestic non-dominant...

Agency IP Data

Data.gov (United States)

National Aeronautics and Space Administration — Public data set for NASA Agency Intellectual Property (IP). The distribution contains both Patent information as well as General Release of Open Source Software.

A PEC 65 E O PLANEJAMENTO URBANO NO BRASIL: Um recorte sobre a inobservância dos direitos da sociedade civil em questões de meio ambiente nas estratégias de governo

Directory of Open Access Journals (Sweden)

Ingrid Elena Schnoor

2017-02-01

Full Text Available A Avaliação de Impacto Ambiental (AIA é o instrumento-modelo vigente que auxilia no planejamento e na tomada de decisão sobre empreendimentos que impactem negativamente o meio ambiente. É um instrumento técnico-racional, a ser aplicado sobre situações complexas. Mesmo sendo vital para a gestão da ação antrópica sobre os recursos e sobre o meio ambiente no planeta, por sua idade, (surgiu nos anos 60 do século XX, está, ainda, em processo de desenvolvimento e amadurecimento. E, por seu caráter regulador que impõe dificuldades ao avanço de empreendimentos econômicos, incomoda. Se a forma de avaliar (linear e contínua não dialoga com os problemas decorrentes (complexos, isto pode levar a um resultado tendencioso e incompleto, passível de questionamento sobre sua eficácia. É o que se tem visto. Este artigo expõe a Proposta de Emenda Constitucional, PEC 65/2012, em tramitação para aprovação, cujo texto tenta anular a eficácia da AIA e calar a voz da sociedade, fazendo um breve recorte histórico para mostrar os riscos de tal aprovação se concretizar.

Research of future network with multi-layer IP address

Science.gov (United States)

Li, Guoling; Long, Zhaohua; Wei, Ziqiang

2018-04-01

The shortage of IP addresses and the scalability of routing systems [1] are challenges for the Internet. The idea of dividing existing IP addresses between identities and locations is one of the important research directions. This paper proposed a new decimal network architecture based on IPv9 [11], and decimal network IP address from E.164 principle of traditional telecommunication network, the IP address level, which helps to achieve separation and identification and location of IP address, IP address form a multilayer network structure, routing scalability problem in remission at the same time, to solve the problem of IPv4 address depletion. On the basis of IPv9, a new decimal network architecture is proposed, and the IP address of the decimal network draws on the E.164 principle of the traditional telecommunication network, and the IP addresses are hierarchically divided, which helps to realize the identification and location separation of IP addresses, the formation of multi-layer IP address network structure, while easing the scalability of the routing system to find a way out of IPv4 address exhausted. In addition to modifying DNS [10] simply and adding the function of digital domain, a DDNS [12] is formed. At the same time, a gateway device is added, that is, IPV9 gateway. The original backbone network and user network are unchanged.

IP Address Management Principles and Practice

CERN Document Server

Rooney, Timothy

2010-01-01

This book will be the first covering the subject of IP address management (IPAM). The practice of IPAM includes the application of network management disciplines to IP address space and associated network services, namely DHCP (Dynamic Host Configuration Protocol) and DNS (Domain Name System). The consequence of inaccurately configuring DHCP is that end users may not be able to obtain IP addresses to access the network. Without proper DNS configuration, usability of the network will greatly suffer as the name-to-address lookup process may fail. Imagine having to navigate to a website or send a

Operational Space Weather Products at IPS

Science.gov (United States)

Neudegg, D.; Steward, G.; Marshall, R.; Terkildsen, M.; Kennewell, J.; Patterson, G.; Panwar, R.

2008-12-01

IPS Radio and Space Services operates an extensive network (IPSNET) of monitoring stations and observatories within the Australasian and Antarctic regions to gather information on the space environment. This includes ionosondes, magnetometers, GPS-ISM, oblique HF sounding, riometers, and solar radio and optical telescopes. IPS exchanges this information with similar organisations world-wide. The Regional Warning Centre (RWC) is the Australian Space Forecast Centre (ASFC) and it utilizes this data to provide products and services to support customer operations. A wide range of customers use IPS services including; defence force and emergency services using HF radio communications and surveillance systems, organisations involved in geophysical exploration and pipeline cathodic protection, GPS users in aviation. Subscriptions to the alerts, warnings, forecasts and reports regarding the solar, geophysical and ionospheric conditions are distributed by email and Special Message Service (SMS). IPS also develops and markets widely used PC software prediction tools for HF radio skywave and surface wave (ASAPS/GWPS) and provides consultancy services for system planning.

La mirada social en la prensa: Concepción Arenal

Directory of Open Access Journals (Sweden)

Simón Palmer, María del Carmen

2014-06-01

Full Text Available In La Voz de la Caridad Concepción Arenal set out her views on a series of social problems that remain current even today, although though they have not received as much attention as those relating to women, prisoners, or poverty.Concepción Arenal dejó en La Voz de la Caridad, sus opiniones sobre una serie de problemas sociales que, aún hoy, siguen de plena actualidad aunque no han merecido tanta atención como los referentes a la mujer, los presos o la pobreza.

A bulimia nervosa como fator de risco para distúrbios da voz: artigo de revisão Bulimia nervosa as a risk factor for voice disorders: literature review

Directory of Open Access Journals (Sweden)

Patricia Balata

2008-06-01

Full Text Available A bulimia nervosa é um tipo de transtorno alimentar que tem início na adolescência e que apresenta uma variedade de sintomas, dentre estes, os episódios recorrentes de vômitos que acometem a cavidade oral, podendo alcançar a laringe de forma semelhante ao refluxo gastroesofágico, ocasionando alterações laríngeas e distúrbios na voz. OBJETIVO: Este trabalho teve como objetivo investigar através da revista da literatura os estudos que relacionassem a BN como fator de risco para os distúrbios da voz. RESULTADOS: Dos noventa e três artigos levantados, vinte e três foram usados como base para esta revisão, dentre os quais, apenas três referem-se à BN com fator etiológico de alterações na voz em mulheres adultas, não sendo encontrado nenhum trabalho referindo esta relação em adolescentes bulímicos. CONCLUSÃO: Faz-se necessária a observância de sinais e sintomas laríngeos e vocais que possam estar relacionados à BN, em especial nos adolescentes cuja voz passa por significativas mudanças quando do período da muda vocal.Bulimia nervosa (BN is a type of feeding disorder that starts in adolescence and presents a variety of symptoms, recurrent vomiting in the oral cavity that may reach down to the larynx - similarly to gastro-esophageal reflux, causing laryngeal and voice disorder alterations. AIM: These studies aimed at surveying the literature and investigate the studies that considered BN a risk factor for voice disorders. RESULTS: of the ninety three papers we found, twenty-three were used as a basis for this review, among them, only three discuss BN as an etiology factor associated with voice changes in adult women, and we did not find any paper associating this with bulimic teenagers. CONCLUSION: It is necessary to observe laryngeal and vocal signs and symptoms associated with BN, especially in teenagers whose voices are going through a period of change.

Parallel factor ChIP provides essential internal control for quantitative differential ChIP-seq.

Science.gov (United States)

Guertin, Michael J; Cullen, Amy E; Markowetz, Florian; Holding, Andrew N

2018-04-17

A key challenge in quantitative ChIP combined with high-throughput sequencing (ChIP-seq) is the normalization of data in the presence of genome-wide changes in occupancy. Analysis-based normalization methods were developed for transcriptomic data and these are dependent on the underlying assumption that total transcription does not change between conditions. For genome-wide changes in transcription factor (TF) binding, these assumptions do not hold true. The challenges in normalization are confounded by experimental variability during sample preparation, processing and recovery. We present a novel normalization strategy utilizing an internal standard of unchanged peaks for reference. Our method can be readily applied to monitor genome-wide changes by ChIP-seq that are otherwise lost or misrepresented through analytical normalization. We compare our approach to normalization by total read depth and two alternative methods that utilize external experimental controls to study TF binding. We successfully resolve the key challenges in quantitative ChIP-seq analysis and demonstrate its application by monitoring the loss of Estrogen Receptor-alpha (ER) binding upon fulvestrant treatment, ER binding in response to estrodiol, ER mediated change in H4K12 acetylation and profiling ER binding in patient-derived xenographs. This is supported by an adaptable pipeline to normalize and quantify differential TF binding genome-wide and generate metrics for differential binding at individual sites.

Dynamic Mobile IP routers in ad hoc networks

NARCIS (Netherlands)

Kock, B.A.; Schmidt, J.R.

2005-01-01

This paper describes a concept combining mobile IP and ad hoc routing to create a robust mobile network. In this network all nodes are mobile and globally and locally reachable under the same IP address. Essential for implementing this network are the dynamic mobile IP routers. They act as gateways

VoIP over WLAN

OpenAIRE

Nikkari, Joni

2007-01-01

Tässä opinnäytetyössä tutkitaan VoIP over WLAN -tekniikan mahdollisuuksia nykyaikaisessa käyttöympäristössä, sekä yritysmaailman että kotikäyttäjän näkökulmasta. Toimiakseen VoWLAN tarvitsee kaksi eri tekniikkaa: langattoman lähiverkon sekä WLAN-puhelimen, joka perustuu VoIP-tekniikkaan.; WLAN:ssa tietoliikenne kulkee normaalin kaapeloinnin sijasta radiotaajuuksia käyttämällä. Standardina toimii IEEE 802.11, joka määrittelee WLAN-verkkojen toiminnan. Standardia on kehitetty jatkuvasti, ja si...

Protection against cancer by dietary IP6 and inositol.

Science.gov (United States)

Vucenik, Ivana; Shamsuddin, AbulKalam M

2006-01-01

Inositol hexaphosphate (IP(6)) is a naturally occurring polyphosphorylated carbohydrate, abundantly present in many plant sources and in certain high-fiber diets, such as cereals and legumes. In addition to being found in plants, IP(6) is contained in almost all mammalian cells, although in much smaller amounts, where it is important in regulating vital cellular functions such as signal transduction, cell proliferation, and differentiation. For a long time IP(6) has been recognized as a natural antioxidant. Recently IP(6) has received much attention for its role in cancer prevention and control of experimental tumor growth, progression, and metastasis. In addition, IP(6) possesses other significant benefits for human health, such as the ability to enhance immune system, prevent pathological calcification and kidney stone formation, lower elevated serum cholesterol, and reduce pathological platelet activity. In this review we show the efficacy and discuss some of the molecular mechanisms that govern the action of this dietary agent. Exogenously administered IP(6) is rapidly taken up into cells and dephosphorylated to lower inositol phosphates, which further affect signal transduction pathways resulting in cell cycle arrest. A striking anticancer action of IP(6) was demonstrated in different experimental models. In addition to reducing cell proliferation, IP(6) also induces differentiation of malignant cells. Enhanced immunity and antioxidant properties also contribute to tumor cell destruction. Preliminary studies in humans show that IP(6) and inositol, the precursor molecule of IP(6), appear to enhance the anticancer effect of conventional chemotherapy, control cancer metastases, and improve quality of life. Because it is abundantly present in regular diet, efficiently absorbed from the gastrointestinal tract, and safe, IP(6) + inositol holds great promise in our strategies for cancer prevention and therapy. There is clearly enough evidence to justify the

Ifabiyi, IP

African Journals Online (AJOL)

Ifabiyi, IP. Vol 11, No 1 (2013) - Articles Analysis of the Impacts of Rainfall Variability on Public Water Supply in Ilorin, Nigeria Abstract. ISSN: 2006-7003. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's Partners · Terms and Conditions of ...

La voz en la tribuna (El verbo apasionado de Jorge Eliécer Gaitán

Directory of Open Access Journals (Sweden)

Carlos José Reyes

2009-05-01

Full Text Available El uso de la voz humana comoun medio de comunicación einducción frente a la comunidad,se ha desarrollado desde las primerascivilizaciones. Sócrates creóen Grecia la primera escuela deoratoria. En Colombia, uno de lospolíticos y oradores públicos quemás utilizó la oratoria, con su vozvibrante y emotiva, fue el caudilloliberal Jorge Eliécer Gaitán, quienencontró las palabras, los acentos,giros y expresiones adecuadaspara comunicarse con ampliossectores populares. La fuerza desu movimiento lo hubiera llevadoa la presidencia, de no ser por suasesinato, el 9 de abril de 1948.Palabras clave: oratoria, pueblo, a lacarga, mamola, reconquista.

Técnicas de detección de la frecuencia fundamental de la voz en entornos reales

OpenAIRE

Silva Zambrano, María Manuela; Romo Romero, Harold Armando; Ramírez Viáfara, Jesús Mauricio; Galvis Zambrano, Diana María

2017-01-01

Introducción: El artículo de revisión se desarrolló  como parte de un trabajo de maestría en  la Universidad del Cauca durante el año 2017, buscó encontrar los métodos de detección de la frecuencia fundamental de la voz más propicios para implementar en entornos reales, como parte de una solución para mejorar la comunicación de las personas con discapacidad auditiva e incluirlas en la sociedad, ya que la mayoría de las propuestas sólo plantean mejorar el canal de comunicación en el que la per...

La participación del alumnado en los procesos de formación y mejora docente. Una mirada a través de los discursos de orientadores y asesores de formación

Directory of Open Access Journals (Sweden)

Noelia Ceballos López

2014-01-01

Full Text Available Las ideas que en este artículo aparecen se enmarcan en el desarrollo de una tesis doctoral que tiene como objetivo último reflexionar acerca de cómo podemos incorporar, en los procesos de formación inicial y permanente del profesorado, la voz y participación del alumnado como elemento constitutivo de la práctica docente habitual. Para ello, hemos realizado entrevistas semiestructuradas a asesores de los centros de formación y a orientadores educativos de Cantabria, con la intención de acceder a su espacio teórico y de significado en este campo. Entre las principales conclusiones destacamos la necesidad de incorporar a los procesos de formación docentes la reflexión sobre el propio concepto de participación y voz del alumnado así como sobre el sentido y alcance de las experiencias que bajo esta idea se desarrollan actualmente en los centros educativos. Al mismo tiempo, concluimos que la participación y voz del alumnado puede ser considerado una herramienta de mejora escolar que ayude a los docentes a pensar sobre su práctica pedagógica en la construcción de una nueva cultura profesional docente que defiende la democracia Esto supone por tanto, un cambio en cómo se concibe la formación docente y el papel que asesores y orientadores tienen en él.

Factores ambientales y hábitos vocales en docentes y funcionarios de pre-escolar con alteraciones de voz

OpenAIRE

Barreto, Deisy Paola; Cháux Ramos, Oriana Mireya; Estrada Rangel, Monica Andrea; Sánchez Morales, Jenifer; Moreno Angarita, Marisol; Camargo Mendoza, Maryluz

2012-01-01

Objetivo Determinar la relación existente entre los hábitos vocales y condiciones ambientales/ ocupacionales, con la presencia de alteraciones vocales (disfonía) en docentes y funcionarios de centros sociales de educación inicial. Método Estudio descriptivo transversal en una población de 198 sujetos, que se llevó a cabo en tres fases. Fase 1: Identificación de los sujetos con mayor riesgo de presentar una alteración vocal. Fase 2: Observación-análisis del uso de la voz y los hábitos vocales...

Split degenerate states and stable p+ip phases from holography

Energy Technology Data Exchange (ETDEWEB)

Nie, Zhang-Yu; Zeng, Hui [Kunming University of Science and Technology, Kunming (China); Key Laboratory of Theoretical Physics, Institute of Theoretical Physics, Chinese Academy of Sciences, Beijing (China); Pan, Qiyuan [Hunan Normal Univ., Key Lab. of Low Dimensional Quantum Structures and Quantum Control of Ministry of Education, and Synergetic Innovation Center for Quantum Effects and Applications, Dept. of Physics, Changsha (China); Zeng, Hua-Bi [Yangzhou University, College of Physics Science and Technology, Yangzhou, Jiangsu (China); National Central University, Department of Physics, Chungli (China)

2017-02-15

In this paper, we investigate the p+ip superfluid phases in the complex vector field holographic p-wave model. We find that in the probe limit, the p+ip phase and the p-wave phase are equally stable, hence the p and ip orders can be mixed with an arbitrary ratio to form more general p+λip phases, which are also equally stable with the p-wave and p+ip phases. As a result, the system possesses a degenerate thermal state in the superfluid region. We further study the case on considering the back-reaction on the metric, and we find that the degenerate ground states will be separated into p-wave and p+ip phases, and the p-wave phase is more stable. Finally, due to the different critical temperature of the zeroth order phase transitions from p-wave and p+ip phases to the normal phase, there is a temperature region where the p+ip phase exists but the p-wave phase does not. In this region we find the stable holographic p+ip phase for the first time. (orig.)

IP- -: A Reduced Internet Protocol for Optical Packet Networking

Science.gov (United States)

Ohta, Masataka; Fujikawa, Kenji

IP- - is proposed as an Internet Protocol suitable for optical packet networking. As optical routers require much faster control than electric ones and lack of optical buffers other than those by fiber delay lines requires fixed time control, Internet Protocols must be at least as simple as IPv4 and much simpler than IPv6. IP- - also addresses issues of IP address space exhaustion and IP routing table explosion.

Covert Channels in SIP for VoIP Signalling

Science.gov (United States)

Mazurczyk, Wojciech; Szczypiorski, Krzysztof

In this paper, we evaluate available steganographic techniques for SIP (Session Initiation Protocol) that can be used for creating covert channels during signaling phase of VoIP (Voice over IP) call. Apart from characterizing existing steganographic methods we provide new insights by introducing new techniques. We also estimate amount of data that can be transferred in signalling messages for typical IP telephony call.

DiffServ resource management in IP-based radio access networks

NARCIS (Netherlands)

Heijenk, Geert; Karagiannis, Georgios; Rexhepi, Vlora; Westberg, Lars; prof.dr. Prasad, R.; prof.dr. Bach Andersen, J.

2001-01-01

The increasing popularity of the Internet, the flexibility of IP, and the wide deployment of IP technologies, as well as the growth of mobile communications have driven the development of IP-based solutions for wireless networking. The introduction of IP-based transport in Radio Access Networks

A fast neutron detector with IP by track measurement

International Nuclear Information System (INIS)

Miao Zhengqiang; Yang Jun; Zhang Qiang; Zhao Xiangfeng; Wang Daohua

2004-01-01

Imaging Plate(IP) is very sensitive to electric particles, especially to heavy ions. As we know, the recoiling protons are produced while fast neutrons scattered in light material containing hydrogen. When the recoiling proton enters in the sensitive layer of IP, a track will be recorded by IP. In this paper, a fast neutron detector based on IP and (n, p) reaction is described in detail, the detector's efficiency is studied also. (authors)

Análisis multivariado y QFD como herramientas para escuchar la voz del cliente y mejorar la calidad del servicio

OpenAIRE

Gutiérrez Pulido,Humberto; Gutiérrez González,Porfirio; Garibay López,Cecilia; Díaz Caldera,Lizbeth

2014-01-01

Las organizaciones del sector servicios contribuyen con un alto porcentaje del producto interno bruto de las principales economías del mundo, esto genera la necesidad de buscar alternativas para mejorar los procesos de este sector. Es reconocido que escuchar la voz del cliente es un buen punto de partida para evaluar la calidad de un servicio. Es frecuente que se busque escuchar al cliente aplicando algún cuestionario o encuestas. Sin embargo, debido a los múltiples ítems de las encuestas, es...

Security risks in IP telephony

OpenAIRE

Řezáč, Filip; Vozňák, Miroslav

2010-01-01

This paper deals with VoIP communication security and various techniques of VoIP attacks. We divided these threats in several categories according to their specific behaviour and their impact on the affected system. We also tried to find effective methods to prevent or mitigate these attacks. We focused our work on Spam over Internet Telephony (SPIT) as a real threat for the future. We have developed both a tool generating SPIT attacks and AntiSPIT tool defending communication systems against...

Engineering of radioimmunoassay (RIA) IP10.1

International Nuclear Information System (INIS)

Hari Nurcahyadi

2010-01-01

Engineering of Radioimmunoassay (RIA) IP10.1 is an innovative by PRPN - BATAN in 2010. Innovations made to the device IP10.1 RIA is the sample changer system, sample changer system on the device RIA IP10.1 applied 2 linear axis system (X, Z) with AC servo motor. In the RIA IP10.1 also use 5 pieces of the detector, so the enumeration process 50 (Fifty) sample is expected to be faster. Like its predecessor, The whole enumeration, data collection procedures and mechanisms operating within this system is entirely controlled by a PC via an electronic module. Electronics module consists of a high voltage module, amplifier and signal processor module, the module enumerators, low-voltage module, the module driver motor controller and a USB interface. The data acquisition and communication system using a USB port with the computer. (author)

iTAR: a web server for identifying target genes of transcription factors using ChIP-seq or ChIP-chip data.

Science.gov (United States)

Yang, Chia-Chun; Andrews, Erik H; Chen, Min-Hsuan; Wang, Wan-Yu; Chen, Jeremy J W; Gerstein, Mark; Liu, Chun-Chi; Cheng, Chao

2016-08-12

Chromatin immunoprecipitation followed by massively parallel DNA sequencing (ChIP-seq) or microarray hybridization (ChIP-chip) has been widely used to determine the genomic occupation of transcription factors (TFs). We have previously developed a probabilistic method, called TIP (Target Identification from Profiles), to identify TF target genes using ChIP-seq/ChIP-chip data. To achieve high specificity, TIP applies a conservative method to estimate significance of target genes, with the trade-off being a relatively low sensitivity of target gene identification compared to other methods. Additionally, TIP's output does not render binding-peak locations or intensity, information highly useful for visualization and general experimental biological use, while the variability of ChIP-seq/ChIP-chip file formats has made input into TIP more difficult than desired. To improve upon these facets, here we present are fined TIP with key extensions. First, it implements a Gaussian mixture model for p-value estimation, increasing target gene identification sensitivity and more accurately capturing the shape of TF binding profile distributions. Second, it enables the incorporation of TF binding-peak data by identifying their locations in significant target gene promoter regions and quantifies their strengths. Finally, for full ease of implementation we have incorporated it into a web server ( http://syslab3.nchu.edu.tw/iTAR/ ) that enables flexibility of input file format, can be used across multiple species and genome assembly versions, and is freely available for public use. The web server additionally performs GO enrichment analysis for the identified target genes to reveal the potential function of the corresponding TF. The iTAR web server provides a user-friendly interface and supports target gene identification in seven species, ranging from yeast to human. To facilitate investigating the quality of ChIP-seq/ChIP-chip data, the web server generates the chart of the

An IP-10 (CXCL10)-Derived Peptide Inhibits Angiogenesis

Science.gov (United States)

Yates-Binder, Cecelia C.; Rodgers, Margaret; Jaynes, Jesse; Wells, Alan; Bodnar, Richard J.; Turner, Timothy

2012-01-01

Angiogenesis plays a critical role in processes such as organ development, wound healing, and tumor growth. It requires well-orchestrated integration of soluble and matrix factors and timely recognition of such signals to regulate this process. Previous work has shown that newly forming vessels express the chemokine receptor CXC receptor 3 (CXCR3) and, activation by its ligand IP-10 (CXCL10), both inhibits development of new vasculature and causes regression of newly formed vessels. To identify and develop new therapeutic agents to limit or reverse pathological angiogenesis, we identified a 21 amino acid fragment of IP-10, spanning the α-helical domain residues 77–98, that mimic the actions of the whole IP-10 molecule on endothelial cells. Treatment of the endothelial cells with the 22 amino acid fragment referred to as IP-10p significantly inhibited VEGF-induced endothelial motility and tube formation in vitro, properties critical for angiogenesis. Using a Matrigel plug assay in vivo, we demonstrate that IP-10p both prevented vessel formation and induced involution of nascent vessels. CXCR3 neutralizing antibody was able to block the inhibitory effects of the IP-10p, demonstrating specificity of the peptide. Inhibition of endothelial function by IP-10p was similar to that described for IP-10, secondary to CXCR3-mediated increase in cAMP production, activation of PKA inhibiting cell migration, and inhibition of VEGF-mediated m-calpain activation. IP-10p provides a novel therapeutic agent that inhibits endothelial cell function thus, allowing for the modulation of angiogenesis. PMID:22815829

The ChIP-Seq tools and web server: a resource for analyzing ChIP-seq and other types of genomic data.

Science.gov (United States)

Ambrosini, Giovanna; Dreos, René; Kumar, Sunil; Bucher, Philipp

2016-11-18

ChIP-seq and related high-throughput chromatin profilig assays generate ever increasing volumes of highly valuable biological data. To make sense out of it, biologists need versatile, efficient and user-friendly tools for access, visualization and itegrative analysis of such data. Here we present the ChIP-Seq command line tools and web server, implementing basic algorithms for ChIP-seq data analysis starting with a read alignment file. The tools are optimized for memory-efficiency and speed thus allowing for processing of large data volumes on inexpensive hardware. The web interface provides access to a large database of public data. The ChIP-Seq tools have a modular and interoperable design in that the output from one application can serve as input to another one. Complex and innovative tasks can thus be achieved by running several tools in a cascade. The various ChIP-Seq command line tools and web services either complement or compare favorably to related bioinformatics resources in terms of computational efficiency, ease of access to public data and interoperability with other web-based tools. The ChIP-Seq server is accessible at http://ccg.vital-it.ch/chipseq/ .

In Silico Pooling of ChIP-seq Control Experiments

Science.gov (United States)

Sun, Guannan; Srinivasan, Rajini; Lopez-Anido, Camila; Hung, Holly A.; Svaren, John; Keleş, Sündüz

2014-01-01

As next generation sequencing technologies are becoming more economical, large-scale ChIP-seq studies are enabling the investigation of the roles of transcription factor binding and epigenome on phenotypic variation. Studying such variation requires individual level ChIP-seq experiments. Standard designs for ChIP-seq experiments employ a paired control per ChIP-seq sample. Genomic coverage for control experiments is often sacrificed to increase the resources for ChIP samples. However, the quality of ChIP-enriched regions identifiable from a ChIP-seq experiment depends on the quality and the coverage of the control experiments. Insufficient coverage leads to loss of power in detecting enrichment. We investigate the effect of in silico pooling of control samples within multiple biological replicates, multiple treatment conditions, and multiple cell lines and tissues across multiple datasets with varying levels of genomic coverage. Our computational studies suggest guidelines for performing in silico pooling of control experiments. Using vast amounts of ENCODE data, we show that pairwise correlations between control samples originating from multiple biological replicates, treatments, and cell lines/tissues can be grouped into two classes representing whether or not in silico pooling leads to power gain in detecting enrichment between the ChIP and the control samples. Our findings have important implications for multiplexing samples. PMID:25380244

Security of IP Telephony in Ecuador: Online Analysis

Directory of Open Access Journals (Sweden)

José Estrada

2016-06-01

Full Text Available Telephony is a global service and thus telephone networks have been a coveted target for criminals. Now that voice can be transported over IP and that multiple services are integrated in a convergent model through Internet, there are more incentives to attack and more attackers. Moreover, the development of open source telephone applications has encouraged the massive use of IP telephony, but not an increased awareness about embedded security risks. Due to the current and intensive adoption of IP telephony systems in Ecuador, we conducted an exploration based on public information to obtain statistics about telephone systems connected to Internet in Ecuador. Additionally, using a deliberately vulnerable IP telephony system, we collected more data to do a preliminary analysis of threats to such systems. We found that hundreds of telephone systems were publicly available on the Internet and using outdated versions of Asterisk-based applications. We also found thousands of malicious interactions on the IP telephony system we deployed on the Internet.

Presence in the IP Multimedia Subsystem

Directory of Open Access Journals (Sweden)

Ling Lin

2007-01-01

Full Text Available With an ever increasing penetration of Internet Protocol (IP technologies, the wireless industry is evolving the mobile core network towards all-IP network. The IP Multimedia Subsystem (IMS is a standardised Next Generation Network (NGN architectural framework defined by the 3rd Generation Partnership Project (3GPP to bridge the gap between circuit-switched and packet-switched networks and consolidate both sides into on single all-IP network for all services. In this paper, we provide an insight into the limitation of the presence service, one of the fundamental building blocks of the IMS. Our prototype-based study is unique of its kind and helps identifying the factors which limit the scalability of the current version of the presence service (3GPP TS 23.141 version 7.2.0 Release 7 [1], which will in turn dramatically limit the performance of advanced IMS services. We argue that the client-server paradigm behind the current IMS architecture does not suite the requirements of the IMS system, which defies the very purpose of its introduction. We finally elaborate on possible avenues for addressing this problem.

On-line Monitoring of VoIP Quality Using IPFIX

Directory of Open Access Journals (Sweden)

Petr Matousek

2014-01-01

Full Text Available The main goal of VoIP services is to provide a reliable and high-quality voice transmission over packet networks. In order to prove the quality of VoIP transmission, several approaches were designed. In our approach, we are concerned about on-line monitoring of RTP and RTCP traffic. Based on these data, we are able to compute main VoIP quality metrics including jitter, delay, packet loss, and finally R-factor and MOS values. This technique of VoIP quality measuring can be directly incorporated into IPFIX monitoring framework where an IPFIX probe analyses RTP/RTCP packets, computes VoIP quality metrics, and adds these metrics into extended IPFIX flow records. Then, these extended data are stored in a central IPFIX monitoring system called collector where can be used for monitoring purposes. This paper presents a functional implementation of IPFIX plugin for VoIP quality measurement and compares the results with results obtained by other tools.

Estudo empírico do desempenho dos modelos de gestão de filas FIFO, WFQ e CBWFQ em sistemas reais

OpenAIRE

Sousa, Celso; Fonte, Alexandre

2017-01-01

As aplicações multimédia (e.g., voz ou vídeo) exigem às redes IP um serviço de comunicação com baixa latência, baixas taxas de perdas de pacotes, e requisitos mínimos de largura de banda. Diferentes arquiteturas de Qualidade de Serviço (QoS) foram propostas e desenvolvidas por dois grupos do IETF, o modelo IntServ e o modelo, um pouco mais recente, DiffServ. Os fabricantes de equipamento de rede adotaram as suas próprias implementações destes modelos nos seus equipamentos de encaminhamento IP...

Diseño de un sistema de telefonía IP y plan de empresa para su comercialización

OpenAIRE

Ramal Morcillo, David

2005-01-01

En los últimos años se ha iniciado lo que está destinado a ser una revolución tecnológica y funcional en los servicios de telefonía: la telefonía sobre las redes IP. Por otro lado los modelos de negocio basados en software libre comienzan a desarrollarse y obtener resultados lucrativos. Los dos representan oportunidades para la creación de nuevos negocios. El objetivo de este Proyecto Final de Carrera es demostrar la viabilidad del negocio y la tecnológica de la empresa Innocom. Innocom o...

Mobility management in mobile IP

Science.gov (United States)

Medidi, Sirisha; Golshani, Forouzan

2002-07-01

There is an emerging interest in integrating mobile wireless communication with the Internet based on the Ipv6 technology. Many issues introduced by the mobility of users arise when such an integration is attempted. This paper addresses the problem of mobility management, i.e., that of tracking the current IP addresses of mobile terminals and sustaining active IP connections as mobiles move. The paper presents some architectural and mobility management options for integrating wireless access to the Internet. We then present performance results for Mobile IPv4, route optimization and Mobile IPv6.

Capturing value from Intellectual Property (IP) in a global environment

DEFF Research Database (Denmark)

Alcácer, Juan; Beukel, Karin; Cassiman, Bruno

2017-01-01

Globalization should provide firms with an opportunity to leverage their know-how and reputation across countries to create value. However, it remains challenging for them to actually capture that value using traditional Intellectual Property (IP) tools. In this paper, we document the strong growth...... in patents, trademarks, and industrial designs used by firms to protect their IP globally. We then show that IP protection remains fragmented; the quality of IP applications might be questionable; and developing a comprehensive IP footprint worldwide is very costly. Growing numbers of applications...

Voz do cantor lírico e coordenação motora: uma intervenção baseada em Piret e Béziers Lyric singer voice and motor coordination: an intervention based on Piret and Béziers

Directory of Open Access Journals (Sweden)

Enio Lopes Mello

2009-01-01

Full Text Available OBJETIVO: Investigar os efeitos da aplicação de um Programa de Desenvolvimento da Coordenação Motora, baseado em Piret e Béziers, na voz do cantor lírico. MÉTODOS: Cinco cantores líricos profissionais executaram uma ária de ópera, de livre escolha, que foi filmada. Em seguida responderam a uma questão sobre a propriocepção ao cantar. Durante um mês submeteram-se ao Programa de Desenvolvimento da Coordenação Motora e ao final gravaram novamente a mesma ária e responderam a mesma questão. As filmagens foram enviadas para nove juizes profissionais (três fonoaudiólogos, três fisioterapeutas e três professores de canto que avaliaram a integração corpo e voz dos cantores por meio de análise perceptivo-auditiva e visual. Os cantores, após assistirem às duas filmagens, fizeram outra auto-avaliação. RESULTADOS: Na avaliação dos juízes: as duas sopranos, a mezzo-soprano e o baixo melhoraram a projeção da voz; o tenor melhorou a ressonância e o baixo melhorou também a respiração; com exceção do baixo todos ficaram com os gestos mais livres. Segundo relato dos cantores, os exercícios garantiram maior percepção da tensão muscular durante o canto e isso possibilitou melhor controle dos gestos. CONCLUSÃO: De acordo com a avaliação subjetiva os ajustes posturais, oriundos da execução dos exercícios da coordenação motora, provavelmente garantiram abertura da caixa torácica e melhoraram as condições da respiração dos cantores, durante o canto; este fato pode ter favorecido a verticalização da ressonância e a projeção da voz.PURPOSE: To investigate the effects of the application of a Motor Coordination Development Program, based on Piret and Béziers, on the voice of lyric singers. METHODS: Five professional lyric singers performed an opera aria of their choice, which was filmed. Next, they answered a question regarding their proprioception when singing. They were submitted to the Motor Coordination

Using VoIP to compete.

Science.gov (United States)

Werbach, Kevin

2005-09-01

Internet telephony, or VoIP, is rapidly replacing the conventional kind. This year, for the first time, U.S. companies bought more new Internet-phone connections than standard lines. The major driver behind this change is cost. But VoIP isn't just a new technology for making old-fashioned calls cheaper, says consultant Kevin Werbach. It is fundamentally changing how companies use voice communications. What makes VoIP so powerful is that it turns voice into digital data packets that can be stored, copied, combined with other data, and distributed to virtually any device that connects to the Internet. And it makes it simple to provide all the functionality of a corporate phone-call features, directories, security-to anyone anywhere there's broadband access. That fosters new kinds of businesses such as virtual call centers, where widely dispersed agents work at all hours from their homes. The most successful early adopters, says Werbach, will focus more on achieving business objectives than on saving money. They will also consider how to push VoIP capabilities out to the extended organization, making use of everyone as a resource. Deployment may be incremental, but companies should be thinking about where VoIP could take them. Executives should ask what they could do if, on demand, they could bring all their employees, customers, suppliers, and partners together in a virtual room, with shared access to every modern communications and computing channel. They should take a fresh look at their business processes to find points at which richer and more customizable communications could eliminate bottlenecks and enhance quality. The important dividing line won't be between those who deploy Vol P and those who don't, or even between early adopters and laggards. It will be between those who see Vol P as just a new way to do the same old things and those who use itto rethink their entire businesses.

Study of transmitting electric power utility communications in IP network. Transmission of existing electric power utility communications in best effort type IP network under delay constraint; Denryokuyo tsushin kaisen no IP mo eno shuyo kento. Chien jikan seiyakuka ni okeru best effort gata IP mo eno kison denryokuyo tsushin kaisen no shuyo

Energy Technology Data Exchange (ETDEWEB)

Miyake, H.

2000-07-01

Since IP network does best effort behavior fundamentally, it always generates delay time and delay variation. For this reason, IP network has been unsuitable to transmit real time data such as a voice. However, in recent years, the technologies which transmit real time data in IP network, e.g. VoIP, have spread. If it is possible to transmit the existing electric power utility communications in IP network using these technologies, total network cost can be reduced by the reduction of required bandwidth and the simplification of communication network systems. In this report, it is examined quantitatively whether end-end delay time of the existing electric power utility communications, e.g. on-line, telephone, carrier relay, CDT (cyclic digital transmission equipment), video conference, ITV(industrial television), is within their permission delay time when they are transmitted in the best effort type IP network. (author)

Enabling new e-health business models by converging IP-based and non-IP-based home networks

OpenAIRE

Hartog, F.T.H. den; Tijmes, M.R.; Cramer, E.R.; Noorbergen, A.

2013-01-01

Current efforts in extending the Internet are focused on achieving full support of services and user-centric content from sectors such as energy management, education, and e-health. Until recently, these sectors typically developed their own communication infrastructure and systems, leading to point solutions, often built on non-IP technologies. We describe a demonstrator that shows how a non-IP supporting Continua-certified health device, such as a weighing scale, can be unlocked for use by ...

HPC Access Using KVM over IP

Science.gov (United States)

2007-06-08

Lightwave VDE /200 KVM-over-Fiber (Keyboard, Video and Mouse) devices installed throughout the TARDEC campus. Implementation of this system required...development effort through the pursuit of an Army-funded Phase-II Small Business Innovative Research (SBIR) effort with IP Video Systems (formerly known as...visualization capabilities of a DoD High- Performance Computing facility, many advanced features are necessary. TARDEC-HPC’s SBIR with IP Video Systems

IP3 stimulates CA++ efflux from fusogenic carrot protoplasts

International Nuclear Information System (INIS)

Rincon, M.; Boss, W.F.

1986-01-01

Polyphosphoinositide breakdown plays an important role in signal transduction in animal cells (Berridge and Irvine, 1984, Nature, 312:315). Upon stimulation, phospholipase C hydrolyzes phosphatidylinositol 4,5-bisphosphate to inositol 1,4,5-trisphosphate (IP 3 ) and diacylglycerol both of which act as cellular second messengers. IP 3 mobilizes Ca ++ from internal stores, hence the cytosolic free Ca ++ concentration increases and those physiological activities regulated by Ca ++ are stimulated. To test if plant cells also responded to IP 3 , Ca ++ efflux studies were done with fusogenic carrot protoplasts released in EGTA. The protoplasts were preloaded with 45 Ca ++ placed in a Ca ++ -free medium, and efflux determined as 45 Ca ++ loss from the protoplasts. IP 3 (10-20μM) caused enhanced 45 Ca ++ efflux and the response was sustained for at least 15 min. In plants, as in animals, the observed IP 3 -enhanced 45 Ca ++ efflux suggested that IP 3 released Ca ++ from internal stores, and the increased free cytosolic Ca ++ activated Ca ++ pumping mechanisms which restored the Ca ++ concentration in the cytosol to the normal level

Voz e olhar em Ensaio sobre a cegueira

Directory of Open Access Journals (Sweden)

Heloisa Caldas

2008-01-01

Full Text Available This paper tries to consider the author José Saramago's writing as one which transmits, beyond meaning and imagination, real effects. Such transmission is due to the way this writer treats meaning emptiness. It is based in his book Blindness(SARAMAGO, 1995 commenting the presence of the voice and the look as objects, in the Lacanian sense of the term. According to Lacan, these objects are usually associated, articulated to the desire of the Other and fundamental to the subject in its first appearance. The issue is, therefore, to study the sublimation of these objects distinguishing them from the way they appear in the neurotic and perverse fantasy. That would be a lesson that art creation could give to the object treatment in the psychoanalytical experience.

Voz y voto: participación política y calidad de la democracia en México

Directory of Open Access Journals (Sweden)

Claudio A. HOLZNER

2009-11-01

Full Text Available RESUMEN: La igualdad intrínseca de cada ciudadano es una suposición fundamental de cualquier sistema democrático. Por esto, cualquier evaluación de la calidad de la democracia tiene que considerar la «igualdad de voz», o sea, el grado en que los ciudadanos tienen oportunidades más o menos iguales de participar en la toma de decisiones colectivas. Este ensayo hace una evaluación de la calidad de la democracia en México con especial atención a las desigualdades que existen en la participación política de ciudadanos con niveles de ingresos altos y bajos. Los pobres en México votan menos y participan menos que los ciudadanos de mayores recursos económicos en actividades políticas dirigidas directamente a los gobernantes. Cuando participan tienden a hacerlo en actividades con poca capacidad de comunicar información sobre sus preferencias o de presionar a las autoridades, produciendo las condiciones para que los gobiernos no respondan por igual a las demandas de todos los grupos sociales.ABSTRACT: Because intrinsic equality of each citizen is a fundamental assumption of democracies, any assessments of the quality of democracy must consider the equality of political voice, that is whether a political system provides citizens with more or less equal opportunities to participate in collective decisions. This essay examines patterns of political participation in Mexico to assess whether there are systematic inequalities in the abilities of Mexicans from different income groups to exercise their voice in the political process. The evidence shows that the poor in Mexico vote less often and participate less frequently in government-directed political acts than the wealthy. When they do participate, the poor do so in activities which have little capacity to inform about their needs and preferences, and with little capacity to put pressure on government officials. This creates conditions for governments to not be responsive to or representative

Heterogeneous IP Ecosystem enabling Reuse (HIER)

Science.gov (United States)

2017-03-22

HIER project, DARPA also established additional concepts in the formation of the Common Heterogeneous Integration and IP Reuse Strategies (CHIPS...would need a major change to  business model to offer  Hard  or Soft IP – So CHIPS program can be a better fit to these firms • DoD‐Contractor IP pricing

Mobile IP: state of the art report

NARCIS (Netherlands)

Karagiannis, Georgios; Heijenk, Geert

Due to roaming, a mobile device may change its network attachment each time it moves to a new link. This might cause a disruption for the Internet data packets that have to reach the mobile node. Mobile IP is a protocol, developed by the Mobile IP Internet Engineering Task Force (IETF) working

Quantitative analysis of macro-ARG using IP system

International Nuclear Information System (INIS)

Nakajima, Eiichi; Kawai, Kenji; Furuta, Yoshitake

1997-01-01

Recent progress in imaging plate (IP) system allow us to analyze autoradiographic images quantitatively. In the 'whole-body autoradiography', a method clarify the distribution of radioisotope or labeled compounds in the tissues and organs in a freeze-dried whole-body section of small animals such as rats and mice, the sections are pressed against a IP for exposure and the IP is scanned by Bio-Imaging Analyzer (Fuji Photo Film Co., Ltd) and a digital autoradiographic image is given. Quantitative data concerning the activity in different tissues can be obtained using an isotope scale as a reference source. Fading effect, application of IP system for distribution of receptor binding ARG, analysis of radio-spots on TLC and radioactive concentration in liquid such as blood are also discussed. (author)

Internetworking with TCP/IP

CERN Document Server

Comer, Douglas E

2014-01-01

An internationally best-selling, conceptual introduction to the TCP/IP protocols and Internetworking, this book interweaves a clear discussion of fundamentals and scientific principles with details and examples drawn from the latest technologies. Leading author Douglas Comer covers layering and packet formats for all the Internet protocols, includingTCP, IPv4, IPv6, DHCP, and DNS. In addition, the text explains new trends in Internet systems, including packet classification, Software Defined Networking (SDN), and mesh protocols used in The Internet of Things. The text is appropriate for individuals interested in learning more about TCP/IP protocols, Internet architecture, and current networking technologies, as well as engineers who build network systems. It is suitable for junior to graduate-level courses in Computer Networks, Data Networks, Network Protocols, and Internetworking.

Qualification of Type IP-2, Type IP-3 and Type A packages for radioactive liquid shipments

International Nuclear Information System (INIS)

Marcu, L.; Sullivan, G.; Lo, K.K.

2006-01-01

Commercial products such as pails, drums or bulk containers can be used for radioactive materials transportation if they can be shown to meet the regulatory requirements. Ontario Power Generation (OPG) has successfully tested and qualified several off-the-shelf containers as Type IP-2, Type IP-3 and Type A packages for liquids in accordance with the International and Canadian Regulations. This paper describes the testing and qualification of these commercial products, and discusses the problems encountered and lessons learned during this process. (author)

An Attacker-Defender Model for IP-Based Networks

National Research Council Canada - National Science Library

Barkley, Timothy R

2008-01-01

.... Because IP flows are defined essentially in terms of origin-destination (O-D) pairs, we represent IP traffic engineering as a multi-commodity flow problem in which each O-D pair is treated as a separate commodity...

The wavy Mutation Maps to the Inositol 1,4,5-Trisphosphate 3-Kinase 2 (IP3K2) Gene of Drosophila and Interacts with IP3R to Affect Wing Development.

Science.gov (United States)

Dean, Derek M; Maroja, Luana S; Cottrill, Sarah; Bomkamp, Brent E; Westervelt, Kathleen A; Deitcher, David L

2015-11-27

Inositol 1,4,5-trisphosphate (IP3) regulates a host of biological processes from egg activation to cell death. When IP3-specific receptors (IP3Rs) bind to IP3, they release calcium from the ER into the cytoplasm, triggering a variety of cell type- and developmental stage-specific responses. Alternatively, inositol polyphosphate kinases can phosphorylate IP3; this limits IP3R activation by reducing IP3 levels, and also generates new signaling molecules altogether. These divergent pathways draw from the same IP3 pool yet cause very different cellular responses. Therefore, controlling the relative rates of IP3R activation vs. phosphorylation of IP3 is essential for proper cell functioning. Establishing a model system that sensitively reports the net output of IP3 signaling is crucial for identifying the controlling genes. Here we report that mutant alleles of wavy (wy), a classic locus of the fruit fly Drosophila melanogaster, map to IP3 3-kinase 2 (IP3K2), a member of the inositol polyphosphate kinase gene family. Mutations in wy disrupt wing structure in a highly specific pattern. RNAi experiments using GAL4 and GAL80(ts) indicated that IP3K2 function is required in the wing discs of early pupae for normal wing development. Gradations in the severity of the wy phenotype provide high-resolution readouts of IP3K2 function and of overall IP3 signaling, giving this system strong potential as a model for further study of the IP3 signaling network. In proof of concept, a dominant modifier screen revealed that mutations in IP3R strongly suppress the wy phenotype, suggesting that the wy phenotype results from reduced IP4 levels, and/or excessive IP3R signaling. Copyright © 2016 Dean et al.

The wavy Mutation Maps to the Inositol 1,4,5-Trisphosphate 3-Kinase 2 (IP3K2 Gene of Drosophila and Interacts with IP3R to Affect Wing Development

Directory of Open Access Journals (Sweden)

Derek M. Dean

2016-02-01

Full Text Available Inositol 1,4,5-trisphosphate (IP3 regulates a host of biological processes from egg activation to cell death. When IP3-specific receptors (IP3Rs bind to IP3, they release calcium from the ER into the cytoplasm, triggering a variety of cell type- and developmental stage-specific responses. Alternatively, inositol polyphosphate kinases can phosphorylate IP3; this limits IP3R activation by reducing IP3 levels, and also generates new signaling molecules altogether. These divergent pathways draw from the same IP3 pool yet cause very different cellular responses. Therefore, controlling the relative rates of IP3R activation vs. phosphorylation of IP3 is essential for proper cell functioning. Establishing a model system that sensitively reports the net output of IP3 signaling is crucial for identifying the controlling genes. Here we report that mutant alleles of wavy (wy, a classic locus of the fruit fly Drosophila melanogaster, map to IP3 3-kinase 2 (IP3K2, a member of the inositol polyphosphate kinase gene family. Mutations in wy disrupt wing structure in a highly specific pattern. RNAi experiments using GAL4 and GAL80ts indicated that IP3K2 function is required in the wing discs of early pupae for normal wing development. Gradations in the severity of the wy phenotype provide high-resolution readouts of IP3K2 function and of overall IP3 signaling, giving this system strong potential as a model for further study of the IP3 signaling network. In proof of concept, a dominant modifier screen revealed that mutations in IP3R strongly suppress the wy phenotype, suggesting that the wy phenotype results from reduced IP4 levels, and/or excessive IP3R signaling.

Understanding Innovative Potential (IP) in an ICT Context

DEFF Research Database (Denmark)

Rai, Sudhanshu

a dynamic perspective in its conception, operation and instantiation. I conclude this paper with insights on what I call the dynamic IP threshold arguing that being dynamic cannot be seen as a point in time but a threshold existing over time. I then discuss some implications. I suggest that firms need...... to consider IP as a long term investment not only in human capital but in the way the human capital is allowed to engage with new ideas. I suggest IP can be build using institutional logics that enable openness and collegiality....

Voice over IP in the Local Exchange: A Case Study

OpenAIRE

Weiss, Martin B. H.; Kim, Hak-Ju

2001-01-01

There have been a small number of cost studies of Voice over IP (VoIP) in the academic literature. Generally, they have been for abstract networks, have not been focused on the public switched telephone network, or they have not included the operating costs. This paper presents the operating cost portion of our ongoing research project comparing circuit-switched and IP network costs for an existing local exchange carrier. We have found that (1) The operating cost differential between IP and c...

Security Risks in IP Telephony

Directory of Open Access Journals (Sweden)

Filip Rezac

2010-01-01

Full Text Available This paper deals with VoIP communication security and various techniques of VoIP attacks. We divided these threats in several categories according to their specific behaviour and their impact on the affected system. We also tried to find effective methods to prevent or mitigate these attacks. We focused our work on Spam over Internet Telephony (SPIT as a real threat for the future. We have developed both a tool generating SPIT attacks and AntiSPIT tool defending communication systems against SPIT attacks. AntiSPIT represents an effective protection based on statistical blacklist and works without participation of the called party which is a significant advantage.

Biografía de un cimarrón de Miguel Barnet. La construcción de una voz

Directory of Open Access Journals (Sweden)

Rossana Nofal

2016-04-01

Full Text Available El texto Biografía de un cimarrón del autor cubano Miguel Barnet pertenece a ese ámbito de prácticas discursivas que ha quedado marginado del canon literario. El artículo pretende describir cuáles son las estrategias a las que ha apelado el autor para construir en la escritura una voz oral.   The text Biografía de un cimarrón by the Cuban author Miguel Barnet belongs to that area of reflective practices that has remained on the margins of literary canon. The article attempts to discover the strategies to which the author has appealed in order to construct an oral voice in the writing.

Ade-Ojo, IP

African Journals Online (AJOL)

Ade-Ojo, IP. Vol 40, No 2 (2013) - Articles Myasthenia gravis following chicken pox infection in a Nigerian primary school girl. Abstract PDF. ISSN: 0302-4660. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's Partners · Terms and Conditions ...

Análisis y resultados sobre el uso de la telefonía IP en las Pymes de Cartagena, Bolívar - Colombia

Directory of Open Access Journals (Sweden)

Damián E. Barrios Castillo

2013-12-01

Full Text Available En la ciudad de Cartagena, Colombia, existe un mercado tecnológico que se puede considerar todavía virgen, teniendo en cuenta que la mayoría del producto interno bruto de la ciudad depende de las pequeña y medianas empresas situadas en ella. Uno de estos mercados es el de la Telefonía IP. Realizando un ejercicio de investigación, donde el principal propósito fue identificar cuantas PYMES en la ciudad han implementado en su infraestructura de comunicación la telefonía IP y comprobar que tanto conocimiento se tiene al respecto de esta tecnología y como estas empresas dentro de sus áreas de TI visualizan la utilización de este servicio, buscando así dar indicios de viabilidad de proyectos este sector dentro de la ciudad. Para dar cumplimiento a este objetivo, se planteó una investigación de tipo descriptivo, utilizando la encuesta como técnica de recolección de información para el análisis de la situación real y actual de la telefonía IP en diferentes sectores empresariales. Con los resultados obtenidos se pretende dar a conocer el estado real de esta tecnología en la ciudad y proponer estrategias que permitan la incorporación de la misma en las PYMES.

Mobile location services over the next generation IP core network

DEFF Research Database (Denmark)

Thongthammachart, Saowanee; Olesen, Henning

2003-01-01

network is changing from circuit-switched to packet-switched technology and evolving to an IP core network based on IPv6. The IP core network will allow all IP devices to be connected seamlessly. Due to the movement detection mechanism of Mobile IPv6, mobile terminals will periodically update....... The concept of mobile location services over the next generation IP networks is described. We also discuss the effectiveness of the short-range wireless network regarding a mobile user's position inside buildings and hotspot areas....

La ciudad nos habla

Directory of Open Access Journals (Sweden)

Alfredo Palacios Barra

2014-05-01

La ciudad adquiría allí su lenguaje y su voz se adhería al uso ordenado y humanamente habitable de su urbanidad. ¿Qué duda cabe, entonces, sobre la urgencia de rescatar esa concepción integral de esa Ciudad a escala humana?

Os Corpos que Dançaram suas Vozes

Directory of Open Access Journals (Sweden)

Gisela Reis Biancalana

2016-01-01

Full Text Available O artigo faz uma reflexão sobre a relevância da voz entendida como corpo em movimento. Este entendimento é, primeiramente, pensado à luz dos pressupostos de autores das artes cênicas, teatro e dança. Em seguida, foi lançada uma proposta de processo criador em dança que considerou a colaboração dos performers em seu percurso. A obra de dança foi desenvolvida com atores e teve a voz como principal elemento propulsor. Este trabalho buscou discutir um possível encaminhamento voltado para a pedagogia vocal de performers da cena.

Reflexões sobre uma nova historiografia literária na América LatinaDOI:10.5007/2175-8026.2010n59p113

Directory of Open Access Journals (Sweden)

Eduardo Faria Coutinho

2010-03-01

Full Text Available Com a contribuição de correntes do pensamento como a Desconstrução, a Nova História e os chamados Estudos Culturais e Pós-Coloniais, a Historiografia Literária vem sofrendo, nas últimas décadas, considerável transformação, que se faz sentir pelo questionamento de alguns de seus pilares tradicionais, como as noções de “progressão linear”, “nação”, “idioma” e “literariedade”. Na América Latina, onde a historiografia literária sempre tomou por base os modelos europeus, e deixou de lado a produção de grande parte da população, como os indígenas e africanos, a questão vem inquietando diversos estudiosos, e já deu margem à criação de Histórias Literárias de alto teor inovativo, que dão voz a esses grupos, até então silenciados. Este trabalho consiste numa reflexão sobre esta nova historiografia literária na América Latina, e sobre o papel que ela vem desempenhando no campo dos estudos latino-americanos e de Literatura Comparada de maneira geral.

Biobjective VoIP Service Management in Cloud Infrastructure

Directory of Open Access Journals (Sweden)

Jorge M. Cortés-Mendoza

2016-01-01

Full Text Available Voice over Internet Protocol (VoIP allows communication of voice and/or data over the internet in less expensive and reliable manner than traditional ISDN systems. This solution typically allows flexible interconnection between organization and companies on any domains. Cloud VoIP solutions can offer even cheaper and scalable service when virtualized telephone infrastructure is used in the most efficient way. Scheduling and load balancing algorithms are fundamental parts of this approach. Unfortunately, VoIP scheduling techniques do not take into account uncertainty in dynamic and unpredictable cloud environments. In this paper, we formulate the problem of scheduling of VoIP services in distributed cloud environments and propose a new model for biobjective optimization. We consider the special case of the on-line nonclairvoyant dynamic bin-packing problem and discuss solutions for provider cost and quality of service optimization. We propose twenty call allocation strategies and evaluate their performance by comprehensive simulation analysis on real workload considering six months of the MIXvoip company service.

Limitations and possibilities of low cell number ChIP-seq

Directory of Open Access Journals (Sweden)

Gilfillan Gregor D

2012-11-01

Full Text Available Abstract Background Chromatin immunoprecipitation coupled with high-throughput DNA sequencing (ChIP-seq offers high resolution, genome-wide analysis of DNA-protein interactions. However, current standard methods require abundant starting material in the range of 1–20 million cells per immunoprecipitation, and remain a bottleneck to the acquisition of biologically relevant epigenetic data. Using a ChIP-seq protocol optimised for low cell numbers (down to 100,000 cells / IP, we examined the performance of the ChIP-seq technique on a series of decreasing cell numbers. Results We present an enhanced native ChIP-seq method tailored to low cell numbers that represents a 200-fold reduction in input requirements over existing protocols. The protocol was tested over a range of starting cell numbers covering three orders of magnitude, enabling determination of the lower limit of the technique. At low input cell numbers, increased levels of unmapped and duplicate reads reduce the number of unique reads generated, and can drive up sequencing costs and affect sensitivity if ChIP is attempted from too few cells. Conclusions The optimised method presented here considerably reduces the input requirements for performing native ChIP-seq. It extends the applicability of the technique to isolated primary cells and rare cell populations (e.g. biobank samples, stem cells, and in many cases will alleviate the need for cell culture and any associated alteration of epigenetic marks. However, this study highlights a challenge inherent to ChIP-seq from low cell numbers: as cell input numbers fall, levels of unmapped sequence reads and PCR-generated duplicate reads rise. We discuss a number of solutions to overcome the effects of reducing cell number that may aid further improvements to ChIP performance.

A survey of IP over ATM architectures

Energy Technology Data Exchange (ETDEWEB)

Chen, H.; Tsang, R.; Brandt, J.; Hutchins, J.

1997-07-01

Over the past decade, the Internet has burgeoned into a worldwide information highway consisting of approximately 5 million hosts on over 45,000 interconnected networks. This unprecedented growth, together with the introduction of multimedia workstations, has spurred the development of innovative applications that require high speed, low latency, and real-time transport. Today`s Internet can neither scale in its bandwidth nor guarantee the Quality of Services (QoS) necessary to meet these performance requirements. Many network researchers propose to use the Asynchronous Transfer Mode (ATM) technology as the underlying infrastructure for the next generation of workgroup, campus, and enterprise IP networks. Since ATM is significantly different from today`s legacy network technologies, efficient implementation of IP over ATM is especially challenging. This tutorial paper covers several existing proposals that integrate IP over ATM.

Secure IP mobility management for VANET

CERN Document Server

Taha, Sanaa

2013-01-01

This brief presents the challenges and solutions for VANETs' security and privacy problems occurring in mobility management protocols including Mobile IPv6 (MIPv6), Proxy MIPv6 (PMIPv6), and Network Mobility (NEMO). The authors give an overview of the concept of the vehicular IP-address configurations as the prerequisite step to achieve mobility management for VANETs, and review the current security and privacy schemes applied in the three mobility management protocols. Throughout the brief, the authors propose new schemes and protocols to increase the security of IP addresses within VANETs in

A voz das crianças sobre sua educação escolar no Rio Grande do Norte

Directory of Open Access Journals (Sweden)

Cristine Tinoco da Cunha Lima Rosado

2010-08-01

Full Text Available Quais as concepções das crianças acerca do seu direito ao Ensino Fundamental, como etapa obrigatória da educação básica? Que avaliações são feitas pelas crianças sobre a escola de Ensino Fundamental, quanto a sua finalidade, prática pedagógica e aquisições proporcionadas aos seus destinatários notadamente no que concerne à alfabetização? São questões de pesquisa que nortearam a elaboração deste trabalho. Visando respondê-las, trabalhamos com 20 crianças dos anos iniciais do ensino fundamental de duas escolas: uma estadual e outra municipal, tendo, como eixo fundante da pesquisa, a fala das crianças acerca do seu contexto escolar. Como resultado inicial, alertamos os atores da dinâmica escolar a lançarem um olhar mais acurado para o que dizem as crianças e como delineiam o seu lócus principal de aprendizagens sistematizadas.

La agenda temática sobre Educación en la prensa digital: las TIC entre otros temas

Directory of Open Access Journals (Sweden)

Juan Antonio GAITÁN MOYA

2007-01-01

Full Text Available Se analiza en este artículo los temas presentes en la Agenda sobre Educación en los periódicos de ámbito nacional ABC, El País, El Mundo y La Razón, y en los diarios de ámbito regional El Correo, La Voz de Galicia y La Vanguardia. En el análisis aparecen treinta y dos temas relativos a la Educación, entre los cuales los más destacados son la reforma educativa, la violencia escolar, la religión en la escuela, la oferta docente y no lectiva, la demanda de infraestructura y el aumento de la inmigración, las TIC, la financiación de la educación, la calidad escolar y el fracaso escolar, las lenguas y los nacionalismos y la investigación. Entre otras cuestiones se da cuenta del orden de importancia de los temas referidos según su frecuencia de aparición, contenidos y orden de ocurrencia.

Secure Protocol and IP Core for Configuration of Networking Hardware IPs in the Smart Grid

Directory of Open Access Journals (Sweden)

Marcelo Urbina

2018-02-01

Full Text Available Nowadays, the incorporation and constant evolution of communication networks in the electricity sector have given rise to the so-called Smart Grid, which is why it is necessary to have devices that are capable of managing new communication protocols, guaranteeing the strict requirements of processing required by the electricity sector. In this context, intelligent electronic devices (IEDs with network architectures are currently available to meet the communication, real-time processing and interoperability requirements of the Smart Grid. The new generation IEDs include an Field Programmable Gate Array (FPGA, to support specialized networking switching architectures for the electric sector, as the IEEE 1588-aware High-availability Seamless Redundancy/Parallel Redundancy Protocol (HSR/PRP. Another advantage to using an FPGA is the ability to update or reconfigure the design to support new requirements that are being raised to the standards (IEC 61850. The update of the architecture implemented in the FPGA can be done remotely, but it is necessary to establish a cyber security mechanism since the communication link generates vulnerability in the case the attacker gains physical access to the network. The research presented in this paper proposes a secure protocol and Intellectual Property (IP core for configuring and monitoring the networking IPs implemented in a Field Programmable Gate Array (FPGA. The FPGA based implementation proposed overcomes this issue using a light Layer-2 protocol fully implemented on hardware and protected by strong cryptographic algorithms (AES-GCM, defined in the IEC 61850-90-5 standard. The proposed secure protocol and IP core are applicable in any field where remote configuration over Ethernet is required for IP cores in FPGAs. In this paper, the proposal is validated in communications hardware for Smart Grids.

Intellectual Property and Strategic Agreements (IP/SA) | FNLCR Staging

Science.gov (United States)

IP/SA handles all invention issues including patents and copyrights. All employee inventionreports are filed through the IP/SA office for all activities under the OTS contract.Additionally,request for assignment ofcopyri

Prognostic value of CtIP/RBBP8 expression in breast cancer

International Nuclear Information System (INIS)

Soria-Bretones, Isabel; Sáez, Carmen; Ruíz-Borrego, Manuel; Japón, Miguel A; Huertas, Pablo

2013-01-01

CtIP/RBBP8 is a multifunctional protein involved in transcription, DNA replication, DNA repair by homologous recombination and the G1 and G2 checkpoints. Its multiple roles are controlled by its interaction with several specific factors, including the tumor suppressor proteins BRCA1 and retinoblastoma. Both its functions and interactors point to a putative oncogenic potential of CtIP/RBBP8 loss. However, CtIP/RBBP8 relevance in breast tumor appearance, development, and prognosis has yet to be established. We performed a retrospective analysis of CtIP/RBBP8 and RB1 levels by immunohistochemistry using 384 paraffin-embedded breast cancer biopsies obtained during tumor removal surgery. We have observed that low or no expression of CtIP/RBBP8 correlates with high-grade breast cancer and with nodal metastasis. Reduction on CtIP/RBBP8 is most common in hormone receptor (HR)-negative, HER2-positive, and basal-like tumors. We observed lower levels of RB1 on those tumors with reduced CtIP/RBBP8 levels. On luminal tumors, decreased but not absence of CtIP/RBBP8 levels correlate with increased disease-free survival when treated with a combination of hormone, radio, and chemo therapies

Integrating QoS and security functions in an IP-VPN gateway

Science.gov (United States)

Fan, Kuo-Pao; Chang, Shu-Hsin; Lin, Kuan-Ming; Pen, Mau-Jy

2001-10-01

IP-based Virtual Private Network becomes more and more popular. It can not only reduce the enterprise communication cost but also increase the revenue of the service provider. The common IP-VPN application types include Intranet VPN, Extranet VPN, and remote access VPN. For the large IP-VPN market, some vendors develop dedicated IP-VPN devices; while some vendors add the VPN functions into their existing network equipment such as router, access gateway, etc. The functions in the IP-VPN device include security, QoS, and management. The common security functions supported are IPSec (IP Security), IKE (Internet Key Exchange), and Firewall. The QoS functions include bandwidth control and packet scheduling. In the management component, policy-based network management is under standardization in IETF. In this paper, we discuss issues on how to integrate the QoS and security functions in an IP-VPN Gateway. We propose three approaches to do this. They are (1) perform Qos first (2) perform IPSec first and (3) reserve fixed bandwidth for IPSec. We also compare the advantages and disadvantages of the three proposed approaches.

China's Indigenous IP Policies -- Here to Stay?

OpenAIRE

Prud'homme, Dan

2013-01-01

In 2010 and 2011, foreign businesses and governments welcomed measures believed to dramatically reform a highly controversial branch of China’s indigenous innovation policy which provided government procurement preferences to applicants who can meet restrictive indigenous intellectual property (IP) rights requirements. However, this article describes specific examples of (what can be labeled) China’s “indigenous IP policy” that are still very much in force, in particular several programs link...

Internetiside VoIP sobib ka ettevõtteile / Valdur Laid

Index Scriptorium Estoniae

Laid, Valdur, 1969-

2005-01-01

Ilmunud ka: Delovõje Vedomosti 8. juuni lk. 19. Kommunikatsiooni liikumisest internetti ehk IP-võrku ning selle võimalustest ettevõtjaile. Vt. samas: Väikefirmade IP-lahendus jõuab aasta lõpus massturule

O jornal A Voz da Escola: escritas dos alunos do Colégio Elementar Souza Lobo (Porto Alegre/RS - 1934/1940 - The journal A Voz da Escola: written by children of the Elementary School Souza Lobo (Porto Alegre/RS - 1934/1940

Directory of Open Access Journals (Sweden)

Maria Helena Camara Bastos

2013-04-01

Full Text Available O artigo aborda as escritas de alunos do ensino primário do Colégio Elementar Souza Lobo (Porto Alegre/RS, publicadas no jornal A Voz da Escola (1934-1940, como prática de formação pessoal, cívica e religiosa, de aprendizagem da moral ou da civilidade. Busca-se analisar os discursos veiculados, os processos de subjetivação e suas influências nos modos como as crianças, na faixa etária de 10 a 12 anos, pensavam, agiam e se expressavam nos espaços de construção de suas identidades. Insere-se nas práticas de escritas escolares e infantis, especialmente na interface da História da Educação e da história da cultura escrita, que analisa a produção, difusão, conservação e o uso dos objetos escritos, em suas várias modalidades. Os exemplares do periódico são tomados como lócus privilegiado para adentrarmos no cotidiano de uma escola primária, da década de 1930, isto é, o universo escolar e toda uma rede paralela de significações.Palavras-chaves: escrita infantil, jornal escolar, periódico estudantil, cultura escolar. THE JOURNAL A VOZ DA ESCOLA: WRITTEN BY CHILDREN OF THE ELEMENTARY SCHOOL SOUZA LOBO (PORTO ALEGRE/RS - 1934/1940 Abstract The article discusses the writings of primary school pupils of the Elementary School Souza Lobo (Porto Alegre/RS, published in the newspaper A Voz da Escola (1934-1940, as a practice of civic, religious and personal formation, learning of moral or civic education. It aims to analyze conveyed discourses, subjective processes and their influence in way children, aged 10-12, thought, acted and expressed themselves in spaces of construction of their identities. It is inset in the practice of school and children’s writings, especially in the interface of the history of education and the history of written culture, which analyze the production, distribution, conservation and the usage of written objects in their several forms. Copies of the journal are taken as a privileged place in order

All-IP-Ethernet architecture for real-time sensor-fusion processing

Science.gov (United States)

Hiraki, Kei; Inaba, Mary; Tezuka, Hiroshi; Tomari, Hisanobu; Koizumi, Kenichi; Kondo, Shuya

2016-03-01

Serendipter is a device that distinguishes and selects very rare particles and cells from huge amount of population. We are currently designing and constructing information processing system for a Serendipter. The information processing system for Serendipter is a kind of sensor-fusion system but with much more difficulties: To fulfill these requirements, we adopt All IP based architecture: All IP-Ethernet based data processing system consists of (1) sensor/detector directly output data as IP-Ethernet packet stream, (2) single Ethernet/TCP/IP streams by a L2 100Gbps Ethernet switch, (3) An FPGA board with 100Gbps Ethernet I/F connected to the switch and a Xeon based server. Circuits in the FPGA include 100Gbps Ethernet MAC, buffers and preprocessing, and real-time Deep learning circuits using multi-layer neural networks. Proposed All-IP architecture solves existing problem to construct large-scale sensor-fusion systems.

IP validation in remote microelectronics testing

Science.gov (United States)

Osseiran, Adam; Eshraghian, Kamran; Lachowicz, Stefan; Zhao, Xiaoli; Jeffery, Roger; Robins, Michael

2004-03-01

This paper presents the test and validation of FPGA based IP using the concept of remote testing. It demonstrates how a virtual tester environment based on a powerful, networked Integrated Circuit testing facility, aimed to complement the emerging Australian microelectronics based research and development, can be employed to perform the tasks beyond the standard IC test. IC testing in production consists in verifying the tested products and eliminating defective parts. Defects could have a number of different causes, including process defects, process migration and IP design and implementation errors. One of the challenges in semiconductor testing is that while current fault models are used to represent likely faults (stuck-at, delay, etc.) in a global context, they do not account for all possible defects. Research in this field keeps growing but the high cost of ATE is preventing a large community from accessing test and verification equipment to validate innovative IP designs. For these reasons a world class networked IC teletest facility has been established in Australia under the support of the Commonwealth government. The facility is based on a state-of-the-art semiconductor tester operating as a virtual centre spanning Australia and accessible internationally. Through a novel approach the teletest network provides virtual access to the tester on which the DUT has previously been placed. The tester software is then accessible as if the designer is sitting next to the tester. This paper presents the approach used to test and validate FPGA based IPs using this remote test approach.

Unjuk Kerja IP PBX Asterisk dan FreeSWITCH pada Topologi Bertingkat di Jaringan Kampus

Directory of Open Access Journals (Sweden)

Iwan Setiawan

2017-08-01

Full Text Available Internet Protocol-based Private Branch Exchange (IP PBX diperlukan untuk menghubungkan panggilan antar perangkat komunikasi Voice over Internet Protocol (VoIP di sebuah jaringan lokal (LAN. Dengan adanya IP PBX, layanan VoIP dapat disediakan di atas jaringan data/IP yang sudah tergelar. Penelitian ini kami lakukan untuk mengetahui unjuk kerja VoIP pada dua IP PBX yang menggunakan perangkat lunak server Asterisk dan FreeSWITCH. Kami merancang sebuah arsitektur jaringan eksperimen yang diadaptasi dari topologi bertingkat pada jaringan kampus (CAN di lokasi penelitian dengan hierarki perangkat yang terdiri dari core switch, distribution switch, dan access switch. Kedua IP PBX ditempatkan pada hierarki yang berbeda pada topologi jaringan tersebut agar dapat diketahui pengaruhnya terhadap unjuk kerja VoIP. Konsep eksperimen ini diharapkan dapat menjadi salah satu dasar untuk mendesain arsitektur IP PBX secara terpusat dan tersebar pada jaringan kampus. Unjuk kerja VoIP kami ukur dengan parameter-parameter Quality of Service (QoS dan Quality of Experience (QoE. Selain itu, kami juga mengukur konsumsi prosesor dan memori yang dipakai oleh perangkat lunak server VoIP pada saat komunikasi terjadi. Pengukuran dilakukan dengan skenario phone-to-phone pada jaringan eksperimen yang terhubung ke jaringan kampus aktif. Hasil penelitian menunjukkan bahwa penempatan IP PBX di hierarki yang berbeda pada topologi jaringan berpengaruh terhadap unjuk kerja VoIP khususnya pada IP PBX Asterisk. Ketika dibandingkan, unjuk kerja IP PBX FreeSWITCH dalam hal QoS dan QoE sedikit lebih baik daripada Asterisk pada rerata latensi/delay, jitter, Mean Opinion Score (MOS, dan konsumsi memori yaitu 41,012 ms, 0,060 ms, 5, dan 1 % untuk IP PBX 1 serta 41,016 ms, 0,066 ms, 5, dan 0,5 % untuk IP PBX 2

Voice over IP phone calls from your smartphone

CERN Multimedia

2014-01-01

All CERN users do have a Lync account (see here) and can use Instant Messaging, presence and other features. In addition, if your number is activated on Lync IP Phone(1) system then you can make standard phone calls from your computer (Windows/Mac).   Recently, we upgraded the infrastructure to Lync 2013. One of the major features is the possibility to make Voice over IP phone calls from a smartphone using your CERN standard phone number (not mobile!). Install Lync 2013 on iPhone/iPad, Android or Windows Phone, connect to WiFi network and make phone calls as if you were in your office. There will be no roaming charges because you will be using WiFi to connect to CERN phone system(2). Register here to the presentation on Tuesday 29 April at 11 a.m. in the Technical Training Center and see the most exciting features of Lync 2013.   Looking forward to seeing you! The Lync team (1) How to register on Lync IP Phone system: http://information-technology.web.cern.ch/book/lync-ip-phone-serv...

Validation of the Spanish version of the Irrational Procrastination Scale (IPS.

Directory of Open Access Journals (Sweden)

Georgina Guilera

Full Text Available The present study is centered in adapting and validating a Spanish version of the Irrational Procrastination Scale (IPS. The sample consists of 365 adults aged 18-77 years (M = 37.70, SD = 12.64. Participants were administered two measures of procrastination, the IPS and the Decisional Procrastination Questionnaire, as well as the Big Five Inventory, and the Satisfaction With Life Scale. First, the factor and replication analysis revealed that the internal structure of the scale is clearly one-dimensional, supporting the idea that IPS seems to measure general procrastination as a single trait. Second, the internal consistency is satisfactory as is the temporal stability of the IPS scores. Third, the correlations encountered between the IPS scores and other measures of procrastination, personality traits and satisfaction with life are all in the expected direction and magnitude. Finally, consistent with previous research, procrastination is related to age, with the youngest being the most procrastinating group. This study represents the first attempt in adapting and validating the IPS measure of procrastination into Spanish. Results suggest that the Spanish version of the IPS offers valid and reliable scores when applied to adult population.

RIDES: Robust Intrusion Detection System for IP-Based Ubiquitous Sensor Networks.

Science.gov (United States)

Amin, Syed Obaid; Siddiqui, Muhammad Shoaib; Hong, Choong Seon; Lee, Sungwon

2009-01-01

The IP-based Ubiquitous Sensor Network (IP-USN) is an effort to build the "Internet of things". By utilizing IP for low power networks, we can benefit from existing well established tools and technologies of IP networks. Along with many other unresolved issues, securing IP-USN is of great concern for researchers so that future market satisfaction and demands can be met. Without proper security measures, both reactive and proactive, it is hard to envisage an IP-USN realm. In this paper we present a design of an IDS (Intrusion Detection System) called RIDES (Robust Intrusion DEtection System) for IP-USN. RIDES is a hybrid intrusion detection system, which incorporates both Signature and Anomaly based intrusion detection components. For signature based intrusion detection this paper only discusses the implementation of distributed pattern matching algorithm with the help of signature-code, a dynamically created attack-signature identifier. Other aspects, such as creation of rules are not discussed. On the other hand, for anomaly based detection we propose a scoring classifier based on the SPC (Statistical Process Control) technique called CUSUM charts. We also investigate the settings and their effects on the performance of related parameters for both of the components.

Validation of the Spanish version of the Irrational Procrastination Scale (IPS)

Science.gov (United States)

Guilera, Georgina; Penelo, Eva; Morin, Christopher; Steel, Piers; Gómez-Benito, Juana

2018-01-01

The present study is centered in adapting and validating a Spanish version of the Irrational Procrastination Scale (IPS). The sample consists of 365 adults aged 18–77 years (M = 37.70, SD = 12.64). Participants were administered two measures of procrastination, the IPS and the Decisional Procrastination Questionnaire, as well as the Big Five Inventory, and the Satisfaction With Life Scale. First, the factor and replication analysis revealed that the internal structure of the scale is clearly one-dimensional, supporting the idea that IPS seems to measure general procrastination as a single trait. Second, the internal consistency is satisfactory as is the temporal stability of the IPS scores. Third, the correlations encountered between the IPS scores and other measures of procrastination, personality traits and satisfaction with life are all in the expected direction and magnitude. Finally, consistent with previous research, procrastination is related to age, with the youngest being the most procrastinating group. This study represents the first attempt in adapting and validating the IPS measure of procrastination into Spanish. Results suggest that the Spanish version of the IPS offers valid and reliable scores when applied to adult population. PMID:29304119

Validation of the Spanish version of the Irrational Procrastination Scale (IPS).

Science.gov (United States)

Guilera, Georgina; Barrios, Maite; Penelo, Eva; Morin, Christopher; Steel, Piers; Gómez-Benito, Juana

2018-01-01

The present study is centered in adapting and validating a Spanish version of the Irrational Procrastination Scale (IPS). The sample consists of 365 adults aged 18-77 years (M = 37.70, SD = 12.64). Participants were administered two measures of procrastination, the IPS and the Decisional Procrastination Questionnaire, as well as the Big Five Inventory, and the Satisfaction With Life Scale. First, the factor and replication analysis revealed that the internal structure of the scale is clearly one-dimensional, supporting the idea that IPS seems to measure general procrastination as a single trait. Second, the internal consistency is satisfactory as is the temporal stability of the IPS scores. Third, the correlations encountered between the IPS scores and other measures of procrastination, personality traits and satisfaction with life are all in the expected direction and magnitude. Finally, consistent with previous research, procrastination is related to age, with the youngest being the most procrastinating group. This study represents the first attempt in adapting and validating the IPS measure of procrastination into Spanish. Results suggest that the Spanish version of the IPS offers valid and reliable scores when applied to adult population.

ELISA-based assay for IP-10 detection from filter paper samples

DEFF Research Database (Denmark)

Drabe, Camilla Heldbjerg; Blauenfeldt, Thomas; Ruhwald, Morten

2014-01-01

IP-10 is a small pro-inflammatory chemokine secreted primarily from monocytes and fibroblasts. Alterations in IP-10 levels have been associated with inflammatory conditions including viral and bacterial infections, immune dysfunction, and tumor development. IP-10 is increasingly recognized as a b...... as a biomarker that predicts severity of various diseases and can be used in the immunodiagnostics of Mycobacterium tuberculosis and cytomegalovirus infection. Here, we describe an ELISA-based method to detect IP-10 from dried blood and plasma spot samples....

Design of IP Camera Access Control Protocol by Utilizing Hierarchical Group Key

Directory of Open Access Journals (Sweden)

Jungho Kang

2015-08-01

Full Text Available Unlike CCTV, security video surveillance devices, which we have generally known about, IP cameras which are connected to a network either with or without wire, provide monitoring services through a built-in web-server. Due to the fact that IP cameras can use a network such as the Internet, multiple IP cameras can be installed at a long distance and each IP camera can utilize the function of a web server individually. Even though IP cameras have this kind of advantage, it has difficulties in access control management and weakness in user certification, too. Particularly, because the market of IP cameras did not begin to be realized a long while ago, systems which are systematized from the perspective of security have not been built up yet. Additionally, it contains severe weaknesses in terms of access authority to the IP camera web server, certification of users, and certification of IP cameras which are newly installed within a network, etc. This research grouped IP cameras hierarchically to manage them systematically, and provided access control and data confidentiality between groups by utilizing group keys. In addition, IP cameras and users are certified by using PKI-based certification, and weak points of security such as confidentiality and integrity, etc., are improved by encrypting passwords. Thus, this research presents specific protocols of the entire process and proved through experiments that this method can be actually applied.

An ethernet/IP security review with intrusion detection applications

International Nuclear Information System (INIS)

Laughter, S. A.; Williams, R. D.

2006-01-01

Supervisory Control and Data Acquisition (SCADA) and automation networks, used throughout utility and manufacturing applications, have their own specific set of operational and security requirements when compared to corporate networks. The modern climate of heightened national security and awareness of terrorist threats has made the security of these systems of prime concern. There is a need to understand the vulnerabilities of these systems and how to monitor and protect them. Ethernet/IP is a member of a family of protocols based on the Control and Information Protocol (CIP). Ethernet/IP allows automation systems to be utilized on and integrated with traditional TCP/IP networks, facilitating integration of these networks with corporate systems and even the Internet. A review of the CIP protocol and the additions Ethernet/IP makes to it has been done to reveal the kind of attacks made possible through the protocol. A set of rules for the SNORT Intrusion Detection software is developed based on the results of the security review. These can be used to monitor, and possibly actively protect, a SCADA or automation network that utilizes Ethernet/IP in its infrastructure. (authors)

CATCHprofiles: Clustering and Alignment Tool for ChIP Profiles

DEFF Research Database (Denmark)

G. G. Nielsen, Fiona; Galschiøt Markus, Kasper; Møllegaard Friborg, Rune

2012-01-01

IP-profiling data and detect potentially meaningful patterns, the areas of enrichment must be aligned and clustered, which is an algorithmically and computationally challenging task. We have developed CATCHprofiles, a novel tool for exhaustive pattern detection in ChIP profiling data. CATCHprofiles is built upon...... a computationally efficient implementation for the exhaustive alignment and hierarchical clustering of ChIP profiling data. The tool features a graphical interface for examination and browsing of the clustering results. CATCHprofiles requires no prior knowledge about functional sites, detects known binding patterns...... it an invaluable tool for explorative research based on ChIP profiling data. CATCHprofiles and the CATCH algorithm run on all platforms and is available for free through the CATCH website: http://catch.cmbi.ru.nl/. User support is available by subscribing to the mailing list catch-users@bioinformatics.org....

Numerical study of IP3-induced Ca2+ spiral pattern evolution

International Nuclear Information System (INIS)

Tang Jun; Ma Jun; Yi Ming; Jia Ya

2008-01-01

The effect of change in concentration of messenger molecule inositol 1,4,5-trisphosphate (IP 3 ) on intracellular Ca 2+ spiral pattern evolution is studied numerically. The results indicate that when the IP 3 concentration decreases from 0.27 μM, a physiologically reasonable value, to different values, the spiral centre drifts to the edge of the medium and disappears for a small enough IP 3 concentration. The instability of spiral pattern can be understood in terms of excitability-change controlled by the IP 3 concentration. On the other hand, when the IP 3 concentration increases from 0.27 μM, a homogeneous area with a high Ca 2+ concentration emerges and competes with the spiral pattern. A high enough IP 3 concentration can lead the homogeneous area to occupy the whole medium. The instability of spiral pattern is ascribed to the change in stability of a stationary state with a high Ca 2+ concentration. (general)

Application of Mobile-ip to Space and Aeronautical Networks

Science.gov (United States)

Leung, Kent; Shell, Dan; Ivancic, William D.; Stewart, David H.; Bell, Terry L.; Kachmar, Brian A.

2001-01-01

The National Aeronautics and Space Administration (NASA) is interested in applying mobile Internet protocol (mobile-ip) technologies to its space and aeronautics programs. In particular, mobile-ip will play a major role in the Advanced Aeronautic Transportation Technology (AAT-F), the Weather Information Communication (WINCOMM), and the Small Aircraft Transportation System (SATS) aeronautics programs. This paper describes mobile-ip and mobile routers--in particular, the features, capabilities, and initial performance of the mobile router are presented. The application of mobile-router technology to NASA's space and aeronautics programs is also discussed.

Un lunfardismo en Canarias? Algunas observaciones sobre la etimologìa de pibe

Directory of Open Access Journals (Sweden)

Beatriz Gómez-Pablos

1999-12-01

Full Text Available La etimología de la palabra pibe, chico, muchacho, ha dado lugar a numerosas cuestiones y nu­ merosas respuestas por parte de los lexicógrafos. Si se consultan diccionarios de argentinismos se comprobará. que todos ellos señalan el origen italiano de esta voz, pasando en muchos casos por la explicación lunfarda del término. Si se estudian diccionarios españoles podrán observarse diversas opciones: algunos se inclinan por el portugués, otros por el catalán, ninguno de ellos le atribuye etimología italiana. Si se acude entonces a diccionarios de portugués se leerá que este término procede del castellano, y así sucesivamente. Huelga decir que por el conocido fenómeno del plagio lexicográfico, muchas veces las respuestas son idénticas y presentan sólo de vez en cuando matices o informaciones suplementarias que pueden resultar de interés. Naturalmente, existen diccionarios que no ofrecen la etimologia sino marcas de uso y marcas regionales, en parte coincidentes pero en parte también contradictorias. Sobre estos aspectos deseamos hacer algunas observaciones.

Mathematical Representation of VoIP Connection Delay

Directory of Open Access Journals (Sweden)

M. Halas

2007-09-01

Full Text Available The main topic of this article is to define mathematical formulation of VoIP connection delay model. It handles about all partial delay components, the mechanism of their generation, facilities and their mathematical formulation. Thereafter based on mathematical formulation of all partial delay components, the final mathematical model of whole VoIP call delay is created. In conclusion of this article the results of the designed mathematical model are compared with the experimentally gained results.

The Regulatory Challenges and Opportunities of IP Telephony: Perspective on Malaysia

OpenAIRE

Md Khaled Shukran

2011-01-01

IP telephony is a transmission of voice and data over Packet Switched IP Networks and it has become a key issue in the telecommunication industry worldwide because of its higher efficiency and cheapest call rate. Hence, most of the countries in the world set up their telecommunication platform on IP based network as a fast revenue generating sources. Though Malaysia is on the way forward on IP based platform but the growth is not reached at satisfactory level due to the absence of effective r...

Evaluation and Investigation of the Delay in VoIP Networks

Directory of Open Access Journals (Sweden)

V. Janata

2011-06-01

Full Text Available The paper is focused mainly on the delay problems, which considerably influence the final quality of connections in VoIP (Voice over IP networks. The paper provides a detailed exploration of the nature and mechanisms of the delay. The main purpose of the investigation was an attempt to formulate a mathematical model of delay in the VoIP network and its subsequent analysis by laboratory data.

Modeling ChIP sequencing in silico with applications.

Directory of Open Access Journals (Sweden)

Zhengdong D Zhang

2008-08-01

Full Text Available ChIP sequencing (ChIP-seq is a new method for genomewide mapping of protein binding sites on DNA. It has generated much excitement in functional genomics. To score data and determine adequate sequencing depth, both the genomic background and the binding sites must be properly modeled. To develop a computational foundation to tackle these issues, we first performed a study to characterize the observed statistical nature of this new type of high-throughput data. By linking sequence tags into clusters, we show that there are two components to the distribution of tag counts observed in a number of recent experiments: an initial power-law distribution and a subsequent long right tail. Then we develop in silico ChIP-seq, a computational method to simulate the experimental outcome by placing tags onto the genome according to particular assumed distributions for the actual binding sites and for the background genomic sequence. In contrast to current assumptions, our results show that both the background and the binding sites need to have a markedly nonuniform distribution in order to correctly model the observed ChIP-seq data, with, for instance, the background tag counts modeled by a gamma distribution. On the basis of these results, we extend an existing scoring approach by using a more realistic genomic-background model. This enables us to identify transcription-factor binding sites in ChIP-seq data in a statistically rigorous fashion.

Perfil dos profissionais da voz com queixas vocais atendidos em um centro terciário de saúde Profile of voice professionals seen in a tertiary health center

Directory of Open Access Journals (Sweden)

Felipe Sartor Guimarães Fortes

2007-02-01

Full Text Available As laringopatias relacionadas ao trabalho acarretam conseqüências para os profissionais da voz. OBJETIVO: Analisar o perfil destes profissionais atendidos em um hospital terciário. FORMA DE ESTUDO: Estudo de coorte histórica longitudinal. MATERIAL E MÉTODOS: Análise retrospectiva de prontuários. Os diagnósticos foram fornecidos através de videoestrobolaringoscopia. RESULTADOS: Foram atendidos 163 pacientes (119 do sexo feminino, 44 do sexo masculino, idade média de 36,5 anos. Em relação aos grupos profissionais, encontramos profissionais da voz falada (vendedores, professores, telemarketing, recepcionistas, atores e profissionais de saúde e da voz cantada. Os diagnósticos foram: alteração estrutural mínima (33%, nódulos (22%, edema de Reinke (10% e pólipos (6%. Foi observada correlação com tabagismo (p=0,002, sexo (p=0,004 e idade (pWork-related laryngopathy may have negative consequences for voice professionals. AIM: To analyze the profile of voice professionals seen in a tertiary level hospital. STUDY DESIGN: a longitudinal historical cohort. METHODS: A retrospective analysis of patient files. Diagnosis was reached using videostroboscopy. RESULTS: 163 patients (119 females and 44 males were seen. The mean age was 36.5 years. Professionals included spoken voice users (salesman, teachers, telemarketers, receptionists, health professionals and singers. The most frequent diagnoses were: minor structural changes (33%, nodules (22%, Reinke’s edema (10%, and polyps (6%. A correlation was observed between smoking, age and gender; there was an association between smoking and Reinke’s edema, leucoplasia and tabagism, females and Reinke’s edema, nodules and minor structural changes, and also between patients aged over 40 years and Reinke’s edema, and patients under 40 with nodules, laryngitis, and minor structural changes. Symptoms lasted more than 6 months in 74% of patients. CONCLUSION: The profile of voice professionals

Standardization efforts in IP telephony

Science.gov (United States)

Sengodan, Senthil; Bansal, Raj

1999-11-01

The recent interest in IP telephony has led to a tremendous increase of standardization activities in the area. The three main standards bodies in the area of IP telephony are the International Telecommunication Union's (ITU-T) Study Group (SG) 16, the Internet Engineering Task Force (IETF) and the European Telecommunication Standards Institute's (ETSI) TIPHON project. In addition, forums such as the International Multimedia Teleconferencing Consortium (IMTC), the Intelligent Network Forum (INF), the International Softswitch Consortium (ISC), the Electronic Computer Telephony Forum (ECTF), and the MIT's Internet Telephony Consortium (ITC) are looking into various other aspects that aim at the growth of this industry. This paper describes the main tasks (completed and in progress) undertaken by these organizations. In describing such work, an overview of the underlying technology is also provided.

Extraction Of Electronic Evidence From VoIP: Identification & Analysis Of Digital Speech

Directory of Open Access Journals (Sweden)

David Irwin

2012-09-01

Full Text Available The Voice over Internet Protocol (VoIP is increasing in popularity as a cost effective and efficient means of making telephone calls via the Internet. However, VoIP may also be an attractive method of communication to criminals as their true identity may be hidden and voice and video communications are encrypted as they are deployed across the Internet. This produces in a new set of challenges for forensic analysts compared with traditional wire-tapping of the Public Switched Telephone Network (PSTN infrastructure, which is not applicable to VoIP. Therefore, other methods of recovering electronic evidence from VoIP are required.  This research investigates the analysis and recovery of digitised human, which persists in computer memory after a VoIP call.This paper proposes a proof of concept how remnants of digitised human speech from a VoIP call may be identified within a forensic memory capture based on how the human voice is detected via a microphone and encoded to a digital format using the sound card of your personal computer. This digital format is unencrypted whist processed in Random Access Memory (RAM before it is passed to the VoIP application for encryption and  transmission over the Internet. Similarly, an incoming encrypted VoIP call is decrypted by the VoIP application and passes through RAM unencrypted in order to be played via the speaker output.A series of controlled tests were undertaken whereby RAM captures were analysed for remnants of digital speech after a VoIP audio call with known conversation. The identification and analysis of digital speech from RAM attempts to construct an automatic process for the identification and subsequent reconstruction of the audio content of a VoIP call.

O uso da voz e do tablet em narrativas de histórias

Directory of Open Access Journals (Sweden)

Lucirene Andréa Catini Lanzi

2013-08-01

Full Text Available Introdução: Esse estudo parte de atividades desenvolvidas numa biblioteca escolar na cidade de Marília - SP.Objetivo: Abordar o uso da voz e do tablet nas narrativas de histórias.Metodologia: O livro escolhido pela contadora de histórias para essa experiencia foi A menina do Narizinho Arrebitado de Monteiro Lobato, o primeiro livro brasileiro a ganar uma versão interativa para o dispositivo tablet.Resultados: Observou-se nessa atividade como um dispositivo digital entusiasma as crianças, sendo ele uma nova forma de interação com histórias contadas. Com recursos sedutores e fáceis de usar, os tablets proporcionam à leitura níveis de dinamismo e interatividade até aqui impensáveis.Conclusões: Com os resultados dessa pesquisa, conclui-se que os recursos audiovisuais possibilitam interação e dinamismo, proporcionando entusiasmo nos ouvintes; sendo uma ação prazerosa e diversificada que possibilita ao profissional o uso de novas ferramentas para estimular o gosto em ouvir histórias, compartilhá-las e frequentar uma biblioteca escolar.

A Reactive and Cycle-True IP Emulator for MPSoC Exploration

DEFF Research Database (Denmark)

Mahadevan, Shankar; Angiolini, Federico; Sparsø, Jens

2008-01-01

The design of MultiProcessor Systems-on-Chip (MPSoC) emphasizes intellectual-property (IP)-based communication-centric approaches. Therefore, for the optimization of the MPSoC interconnect, the designer must develop traffic models that realistically capture the application behavior as executing...... on the IP core. In this paper, we introduce a Reactive IP Emulator (RIPE) that enables an effective emulation of the IP-core behavior in multiple environments, including bit and cycle-true simulation. The RIPE is built as a multithreaded abstract instruction-set processor, and it can generate reactive...

RIDES: Robust Intrusion Detection System for IP-Based Ubiquitous Sensor Networks

Directory of Open Access Journals (Sweden)

Sungwon Lee

2009-05-01

Full Text Available TheIP-based Ubiquitous Sensor Network (IP-USN is an effort to build the “Internet of things”. By utilizing IP for low power networks, we can benefit from existing well established tools and technologies of IP networks. Along with many other unresolved issues, securing IP-USN is of great concern for researchers so that future market satisfaction and demands can be met. Without proper security measures, both reactive and proactive, it is hard to envisage an IP-USN realm. In this paper we present a design of an IDS (Intrusion Detection System called RIDES (Robust Intrusion DEtection System for IP-USN. RIDES is a hybrid intrusion detection system, which incorporates both Signature and Anomaly based intrusion detection components. For signature based intrusion detection this paper only discusses the implementation of distributed pattern matching algorithm with the help of signature-code, a dynamically created attack-signature identifier. Other aspects, such as creation of rules are not discussed. On the other hand, for anomaly based detection we propose a scoring classifier based on the SPC (Statistical Process Control technique called CUSUM charts. We also investigate the settings and their effects on the performance of related parameters for both of the components.

VoIP under the EU regulatory framework : preventing foreclosure?

NARCIS (Netherlands)

Sadowski, B.M.; Straathof, B.

2005-01-01

In June 2004, the European Commission (EC) issued an "Information and Consultation Document" (European Commission 2004) that discussed how the Regulatory Framework of the European Union (EU) should be adapted to accommodate Voice over IP (VoIP) and invited relevant parties to comment on the

On the implementation of IP protection using biometrics based information hiding and firewall

Science.gov (United States)

Basu, Abhishek; Nandy, Kingshuk; Banerjee, Avishek; Giri, Supratick; Sarkar, Souvik; Sarkar, Subir Kumar

2016-02-01

System-on-chip-based design style creates a revolution in very large scale integration industry with design efficiency, operating speed and development time. To support this process, reuse and exchange of components are essential in electronic form called intellectual property (IP). This, however, increases the possibility of encroachment of IP of the design. So copyright protection of IP against piracy is the most important concern for IP vendors. The existing solutions for IP protection are still not secure enough with flexibility, cost, etc. This paper proposes an information-hiding-based solution for IP protection by embedding a biometric copyright information and firewall inside an IP in the form of a finite state machine with unique configuration. The scheme first introduces biometric signature-based copyright as ownership proof. Second, firewall interrupts the normal functionality of IP at the end of the user time period. The experimental outcomes of field-programmable-gate-array implementation illustrate the efficiency of the proposed method.

On the Cryptographic Features of a VoIP Service

Directory of Open Access Journals (Sweden)

Dimitrios Alvanos

2018-01-01

Full Text Available Security issues of typical Voice over Internet Protocol (VoIP applications are studied in this paper; in particular, the open source Linphone application is being used as a case study. An experimental analysis indicates that protecting signalling data with the TLS protocol, which unfortunately is not always the default option, is needed to alleviate several security concerns. Moreover, towards improving security, it is shown that a VoIP application may operate over a virtual private network without significantly degrading the overall performance. The conclusions of this study provide useful insights to the usage of any VoIP application.

La pérdida de la voz en los maestros, una lectura desde el psicoanálisis

Directory of Open Access Journals (Sweden)

Carlos Alberto Abril Martínez

2009-05-01

Full Text Available Los docentes asumen por encargodel Otro social la función de culminarel proceso de integración de losindividuos más jóvenes a la cultura.Este proceso se ve obstaculizadopor la transformación de pautasrelacionales, la confusión en losroles y por la ausencia del deseode aprender en los estudiantes.Frente a ello se instaura el malestardocente, forma indefinida de dolorpsíquico que afecta la funciónlaboral. Uno de sus síntomas es laafonía. Desde el psicoanálisis, setrata de pensar una posible hipótesisexplicativa de esta situación,con el reconocimiento de que solola apuesta por la palabra puedegenerar un cambio en la posiciónsubjetiva del maestro frente a laexigencia cultural.Palabras clave: malestar docente,objeto voz, sujeto, institución,inhibición.

Análise acústica da voz captada na faringe próximo à fonte glótica através de microfone acoplado ao fibrolaringoscópio Acoustic analysis of voice captured in the pharynx above the glottic source through a microphone on a laryngo-fiberscope

Directory of Open Access Journals (Sweden)

Erica E. Fukuyama

2001-01-01

Full Text Available Objetivo: O objetivo deste trabalho foi estudar a voz próximo à sua fonte produtora, as pregas vocais, através de um microfone miniaturizado de aparelho auditivo que foi adaptado para ser acoplado à extremidade de um fibrolaringoscópio, permitindo a captação da voz durante a laringoscopia direta. Forma de estudo: Experimental. Material e Método: A voz foi estudada em um grupo de 50 indivíduos, 25 homens e 25 mulheres sem doenças, através de um programa de análise acústica MDVP (Multi-Dimensional Voice Program do laboratório de voz Computerized Speech Lab, Model 4300B, da Kay Elemetrics. Amostras de vogais sustentadas /a/, /i/ e /u/ foram captadas de três formas diferentes, primeiramente com um microfone comum externo a 15 cm da boca, em segundo lugar com o microfone especial na faringe a 1,5 cm acima das pregas vocais e por último com o microfone especial externamente a 2 cm da boca. Doze parâmetros acústicos relacionados a freqüência fundamental, amplitude e ruído de cada uma das vogais foram comparadas estatisticamente conforme à sua forma de captação. Resultados: Os resultados mostraram diferenças estatisticamente significativas entre a voz captada pelo microfone comum externo e o microfone especial, em relação à freqüência fundamental, aos parâmetros de variação de periodicidade de freqüência, amplitude e ruído. Conclusão: A diferença do som da fonte glótica do som da voz externa pode mostrar as modificações sofridas pela voz no decorrer da passagem pelo trato vocal.Aim: The aim of the present study is to examine the voice to its acoustic source - the vocal folds - with a miniature hearing-aid microphone coupled to the extremity of a laryngo-fiberscope allowing the voice to be captured during direct laryngoscopy. Study design: Experimental. Material and Method: The voice of 50 individuals - 25 males and 25 females bearing no pathologies - was collected by the Multi-Dimensional Voice Program (MDVP by

IP and resistivity survey at the INEL cold test pit

International Nuclear Information System (INIS)

Frangos, W.

1997-01-01

Induced polarization (IP) is a technique for detection of diffuse occurrences of metallic material. The Idaho National Laboratory (INEL) Cold Test Pit (CTP) has been carefully constructed to simulate stored hazardous waste occurrences. IP and resistivity surveys of the CTP show a very strong IP response and a modest resistivity response associated with the simulated waste. Several false positive resistivity anomalies are noted. 2-D inversion of the data accurately determine the lateral limits of the waste zone. The depth of burial indicated is deeper than reported by the construction engineers. Limited depth extent is recognized, in distinction to results from other, resistivity-based, methods, but it also appears too deep. IP holds promise as a method for locating buried waste

Computational Methods for ChIP-seq Data Analysis and Applications

KAUST Repository

Ashoor, Haitham

2017-04-25

The development of Chromatin immunoprecipitation followed by sequencing (ChIP-seq) technology has enabled the construction of genome-wide maps of protein-DNA interaction. Such maps provide information about transcriptional regulation at the epigenetic level (histone modifications and histone variants) and at the level of transcription factor (TF) activity. This dissertation presents novel computational methods for ChIP-seq data analysis and applications. The work of this dissertation addresses four main challenges. First, I address the problem of detecting histone modifications from ChIP-seq cancer samples. The presence of copy number variations (CNVs) in cancer samples results in statistical biases that lead to inaccurate predictions when standard methods are used. To overcome this issue I developed HMCan, a specially designed algorithm to handle ChIP-seq cancer data by accounting for the presence of CNVs. When using ChIP-seq data from cancer cells, HMCan demonstrates unbiased and accurate predictions compared to the standard state of the art methods. Second, I address the problem of identifying changes in histone modifications between two ChIP-seq samples with different genetic backgrounds (for example cancer vs. normal). In addition to CNVs, different antibody efficiency between samples and presence of samples replicates are challenges for this problem. To overcome these issues, I developed the HMCan-diff algorithm as an extension to HMCan. HMCan-diff implements robust normalization methods to address the challenges listed above. HMCan-diff significantly outperforms another state of the art methods on data containing cancer samples. Third, I investigate and analyze predictions of different methods for enhancer prediction based on ChIP-seq data. The analysis shows that predictions generated by different methods are poorly overlapping. To overcome this issue, I developed DENdb, a database that integrates enhancer predictions from different methods. DENdb also

IP over optical multicasting for large-scale video delivery

Science.gov (United States)

Jin, Yaohui; Hu, Weisheng; Sun, Weiqiang; Guo, Wei

2007-11-01

In the IPTV systems, multicasting will play a crucial role in the delivery of high-quality video services, which can significantly improve bandwidth efficiency. However, the scalability and the signal quality of current IPTV can barely compete with the existing broadcast digital TV systems since it is difficult to implement large-scale multicasting with end-to-end guaranteed quality of service (QoS) in packet-switched IP network. China 3TNet project aimed to build a high performance broadband trial network to support large-scale concurrent streaming media and interactive multimedia services. The innovative idea of 3TNet is that an automatic switched optical networks (ASON) with the capability of dynamic point-to-multipoint (P2MP) connections replaces the conventional IP multicasting network in the transport core, while the edge remains an IP multicasting network. In this paper, we will introduce the network architecture and discuss challenges in such IP over Optical multicasting for video delivery.

Photometric studies of δ Scuti stars. I. IP Virginis

Science.gov (United States)

Joner, Michael D.; Hintz, Eric G.; Collier, Matthew W.

1998-01-01

We report 15 new times of maximum light for the δ Scuti star IP Virginis (formerly known as SA 106‐1024). An analysis of all times of maximum light indicates that IP Vir has been decreasing in period at a constant rate of − days day−1. Evidence is also presented that IP Vir is a double‐mode variable with a period ratio of . This period ratio predicts a [Fe/H] value of −0.3. From photometric (uvbyβ) observations, we find a foreground reddening of .008 mag and a metallicity of [Fe/H] = +0.05. It is shown that [Fe/H] = −0.3 is most likely the correct value. Intrinsic ‐ and c1‐values, plotted in a model atmosphere grid, indicate a mean effective temperature, K, and a mean surface gravity, . All of these physical parameters support Landolt's initial conclusion that IP Vir is an ordinary δ Sct star.

Functional-logic simulation of IP-blocks dose functional failures

Directory of Open Access Journals (Sweden)

Vyacheslav M. Barbashov

2017-11-01

Full Text Available The technique of functional-logical simulation of System-on-Chip (SoC total dose radiation failures is presented based on fuzzy logic sets theory. An analysis of the capabilities of this approach for IP-blocks radiation behavior is carried out along with the analysis of operating modes under irradiation influence on IP-blocks radiation behavior. The following elements of this technique application for simulation of dose radiation failures of various types of IP-units are studied: logical elements, memory units and cells, processors. Examples of criterial membership functions and operability functions construction are given for these IP-units and for various critical parameters characterizing their failures. It is shown that when modeling total dose failures it is necessary to take into account the influence of the functional mode on the model parameters. The technique proposed allows improving the reliability of the SoC radiation hardness estimation, also for the purpose of solving the problems of information security of electronic devices.

The psisub(IPS)-LAS relation for extragalactic radio sources

International Nuclear Information System (INIS)

Banhatti, D.G.

1984-01-01

Metre-wavelength interplanetary scintillation (IPS) observations give the overall angular sizes psi of scintillating compact structures in radio sources. From 326.5-MHz IPS data for a sample of faint (Ooty) radio sources, log psi versus log (largest angular size) is seen, on average, to have a slope 0.2, significantly less than one. A similar trend is seen from 81.5-MHz IPS data for a sample of strong, powerful (3CR) double sources, although the slope is 0.4 and the mean psi about four times larger. The difference in slopes is due mainly to the large spread in the redshifts of the 3CR sources compared to the expected narrow range for the Ooty sources, while the difference in mean psi values is due to the different methods of determining psi for the two samples, the different frequencies used for the IPS observations and the different mean LAS values. (author)

CtIP Mutations Cause Seckel and Jawad Syndromes.

Directory of Open Access Journals (Sweden)

Per Qvist

2011-10-01

Full Text Available Seckel syndrome is a recessively inherited dwarfism disorder characterized by microcephaly and a unique head profile. Genetically, it constitutes a heterogeneous condition, with several loci mapped (SCKL1-5 but only three disease genes identified: the ATR, CENPJ, and CEP152 genes that control cellular responses to DNA damage. We previously mapped a Seckel syndrome locus to chromosome 18p11.31-q11.2 (SCKL2. Here, we report two mutations in the CtIP (RBBP8 gene within this locus that result in expression of C-terminally truncated forms of CtIP. We propose that these mutations are the molecular cause of the disease observed in the previously described SCKL2 family and in an additional unrelated family diagnosed with a similar form of congenital microcephaly termed Jawad syndrome. While an exonic frameshift mutation was found in the Jawad family, the SCKL2 family carries a splicing mutation that yields a dominant-negative form of CtIP. Further characterization of cell lines derived from the SCKL2 family revealed defective DNA damage induced formation of single-stranded DNA, a critical co-factor for ATR activation. Accordingly, SCKL2 cells present a lowered apoptopic threshold and hypersensitivity to DNA damage. Notably, over-expression of a comparable truncated CtIP variant in non-Seckel cells recapitulates SCKL2 cellular phenotypes in a dose-dependent manner. This work thus identifies CtIP as a disease gene for Seckel and Jawad syndromes and defines a new type of genetic disease mechanism in which a dominant negative mutation yields a recessively inherited disorder.

Internet Protocol-Hybrid Opto-Electronic Ring Network (IP-HORNET): A Novel Internet Protocol-Over-Wavelength Division Multiplexing (IP-Over-WDM) Multiple-Access Metropolitan Area Network (MAN)

Science.gov (United States)

2003-04-01

IP-HORNET, Metropolitan Optical Networks 16. PRICE CODE 17. SECURITY CLASSIFICATION OF REPORT UNCLASSIFIED 18. SECURITY CLASSIFICATION...OF THIS PAGE UNCLASSIFIED 19. SECURITY CLASSIFICATION OF ABSTRACT UNCLASSIFIED 20. LIMITATION OF ABSTRACT UL NSN 7540-01-280-5500...Gemelos, and L. G. Kazovsky, “CSMA/CA MAC protocols for IP-HORNET: An IP over WDM metropolitan area ring netowrk ,” in Proceedings of GLOBE- COM’00

Esquema de redundancia y distribución de carga de alta disponibilidad para la prestación de telefonía ip usando sip (junio 2009)

OpenAIRE

PARRA L., ANDRÉS; GUERRERO, FABIO G.

2010-01-01

En este artículo se presenta un esquema de distribución de carga y redundancia en la infraestructura de un ISP (Internet Service Provider) para la prestación de servicios de telefonía IP (ITSPs) sobre Internet usando el protocolo SIP (Session Initiation Protocol) garantizando niveles de acceso al servicio similares a la PSTN (Public Switched Telephone Network) y brindando una infraestructura de red escalable. La solución se plantea en tres partes: redundancia del servicio y distribución de ca...

Enabling IP Header Compression in COTS Routers via Frame Relay on a Simplex Link

Science.gov (United States)

Nguyen, Sam P.; Pang, Jackson; Clare, Loren P.; Cheng, Michael K.

2010-01-01

NASA is moving toward a networkcentric communications architecture and, in particular, is building toward use of Internet Protocol (IP) in space. The use of IP is motivated by its ubiquitous application in many communications networks and in available commercial off-the-shelf (COTS) technology. The Constellation Program intends to fit two or more voice (over IP) channels on both the forward link to, and the return link from, the Orion Crew Exploration Vehicle (CEV) during all mission phases. Efficient bandwidth utilization of the links is key for voice applications. In Voice over IP (VoIP), the IP packets are limited to small sizes to keep voice latency at a minimum. The common voice codec used in VoIP is G.729. This new algorithm produces voice audio at 8 kbps and in packets of 10-milliseconds duration. Constellation has designed the VoIP communications stack to use the combination of IP/UDP/RTP protocols where IP carries a 20-byte header, UDP (User Datagram Protocol) carries an 8-byte header, and RTP (Real Time Transport Protocol) carries a 12-byte header. The protocol headers total 40 bytes and are equal in length to a 40-byte G.729 payload, doubling the VoIP latency. Since much of the IP/UDP/RTP header information does not change from IP packet to IP packet, IP/UDP/RTP header compression can avoid transmission of much redundant data as well as reduce VoIP latency. The benefits of IP header compression are more pronounced at low data rate links such as the forward and return links during CEV launch. IP/UDP/RTP header compression codecs are well supported by many COTS routers. A common interface to the COTS routers is through frame relay. However, enabling IP header compression over frame relay, according to industry standard (Frame Relay IP Header Compression Agreement FRF.20), requires a duplex link and negotiations between the compressor router and the decompressor router. In Constellation, each forward to and return link from the CEV in space is treated

Efficient IP Traffic over Optical Network Based on Wavelength Translation Switching

DEFF Research Database (Denmark)

Jha, Vikas; Kalia, Kartik; Chowdhary, Bhawani Shankar

2016-01-01

With the advent of TCP/IP protocol suite the overall era of communication technologies had been redefined. Now, we can’t ignore the presence of huge amount of IP traffic; data, voice or video increasing day by day creating more pressure on existing communicating media and supporting back bone....... With the humongous popularity of Internet the overall traffic on Internet has the same story. Focusing on transmission of IP traffic in an optical network with signals remaining in their optical nature generated at particular wavelength, proposed is the switching of optically generated IP packets through optical...... cross connects based on translation of wavelength when an IP packet is crossing the optical cross connect. Adding the concepts of layer 3 routing protocols along with the wavelength translation scheme, will help in spanning the overall optical network for a larger area....

Capturing value from IP in a global environment

DEFF Research Database (Denmark)

Alcacer, Juan; Beukel, Karin; Cassiman, Bruno

Executive Summary The authors argue that challenges to capturing value from know-how and reputation through the use of different IP tools will be an increasingly important matter of strategy for global enterprises. This has important implications for management practice. Global enterprises...... will need to combine different institutional, market and non-market mechanisms. The precise combination of tools will depend on the local and regional institutional and market conditions. Abstract: This paper documents the strong growth in tools used by firms to protect their intellectual property (IP......), develop their know-how, and build and maintain their reputation globally during the last decades. We focus on three tools: patents, trademarks, and industrial designs. We find that, although most IP applications come from a few countries (the United States, European Union, Japan, China, and South Korea...

Solar Type II Radio Bursts and IP Type II Events

Science.gov (United States)

Cane, H. V.; Erickson, W. C.

2005-01-01

We have examined radio data from the WAVES experiment on the Wind spacecraft in conjunction with ground-based data in order to investigate the relationship between the shocks responsible for metric type II radio bursts and the shocks in front of coronal mass ejections (CMEs). The bow shocks of fast, large CMEs are strong interplanetary (IP) shocks, and the associated radio emissions often consist of single broad bands starting below approx. 4 MHz; such emissions were previously called IP type II events. In contrast, metric type II bursts are usually narrowbanded and display two harmonically related bands. In addition to displaying complete dynamic spectra for a number of events, we also analyze the 135 WAVES 1 - 14 MHz slow-drift time periods in 2001-2003. We find that most of the periods contain multiple phenomena, which we divide into three groups: metric type II extensions, IP type II events, and blobs and bands. About half of the WAVES listings include probable extensions of metric type II radio bursts, but in more than half of these events, there were also other slow-drift features. In the 3 yr study period, there were 31 IP type II events; these were associated with the very fastest CMEs. The most common form of activity in the WAVES events, blobs and bands in the frequency range between 1 and 8 MHz, fall below an envelope consistent with the early signatures of an IP type II event. However, most of this activity lasts only a few tens of minutes, whereas IP type II events last for many hours. In this study we find many examples in the radio data of two shock-like phenomena with different characteristics that occur simultaneously in the metric and decametric/hectometric bands, and no clear example of a metric type II burst that extends continuously down in frequency to become an IP type II event. The simplest interpretation is that metric type II bursts, unlike IP type II events, are not caused by shocks driven in front of CMEs.

The role of calsenilin/DREAM/KChIP3 in contextual fear conditioning.

Science.gov (United States)

Alexander, Jon C; McDermott, Carmel M; Tunur, Tumay; Rands, Vicky; Stelly, Claire; Karhson, Debra; Bowlby, Mark R; An, W Frank; Sweatt, J David; Schrader, Laura A

2009-03-01

Potassium channel interacting proteins (KChIPs) are members of a family of calcium binding proteins that interact with Kv4 potassium (K(+)) channel primary subunits and also act as transcription factors. The Kv4 subunit is a primary K(+) channel pore-forming subunit, which contributes to the somatic and dendritic A-type currents throughout the nervous system. These A-type currents play a key role in the regulation of neuronal excitability and dendritic processing of incoming synaptic information. KChIP3 is also known as calsenilin and as the transcription factor, downstream regulatory element antagonist modulator (DREAM), which regulates a number of genes including prodynorphin. KChIP3 and Kv4 primary channel subunits are highly expressed in hippocampus, an area of the brain important for learning and memory. Through its various functions, KChIP3 may play a role in the regulation of synaptic plasticity and learning and memory. We evaluated the role of KChIP3 in a hippocampus-dependent memory task, contextual fear conditioning. Male KChIP3 knockout (KO) mice showed significantly enhanced memory 24 hours after training as measured by percent freezing. In addition, we found that membrane association and interaction with Kv4.2 of KChIP3 protein was significantly decreased and nuclear KChIP3 expression was increased six hours after the fear conditioning training paradigm with no significant change in KChIP3 mRNA. In addition, prodynorphin mRNA expression was significantly decreased six hours after fear conditioning training in wild-type (WT) but not in KO animals. These data suggest a role for regulation of gene expression by KChIP3/DREAM/calsenilin in consolidation of contextual fear conditioning memories.

Research on TCP/IP network communication based on Node.js

Science.gov (United States)

Huang, Jing; Cai, Lixiong

2018-04-01

In the face of big data, long connection and high synchronization, TCP/IP network communication will cause performance bottlenecks due to its blocking multi-threading service model. This paper presents a method of TCP/IP network communication protocol based on Node.js. On the basis of analyzing the characteristics of Node.js architecture and asynchronous non-blocking I/O model, the principle of its efficiency is discussed, and then compare and analyze the network communication model of TCP/IP protocol to expound the reasons why TCP/IP protocol stack is widely used in network communication. Finally, according to the large data and high concurrency in the large-scale grape growing environment monitoring process, a TCP server design based on Node.js is completed. The results show that the example runs stably and efficiently.

MICROSOFT DYNAMICS CRM IN CISCO IP TELEFONIJA

OpenAIRE

Knez, Margareta

2011-01-01

Microsoft Dynamics CRM je le ena od mnogih rešitev CRM, ki se iz dneva v dan bolj izpopolnjuje in postaja prijaznejša za uporabnike. Na trgu je še mnogo drugih konkurenčnih rešitev programskega orodja CRM. Tako je tudi Ciscova IP-telefonija le ena od mnogih ponudnikov te tehnologije. IP-telefonija bo počasi spodrinila navadno telefonsko linijo, saj je veliko cenejša in ponuja še mnogo dodatnih funkcionalnosti. Le lepa beseda in dobra komunikacija sta potrebni, da stranko zadovoljimo in...

A Novel Addressing Scheme for PMIPv6 Based Global IP-WSNs

Directory of Open Access Journals (Sweden)

Md. Motaharul Islam

2011-08-01

Full Text Available IP based Wireless Sensor Networks (IP-WSNs are being used in healthcare, home automation, industrial control and agricultural monitoring. In most of these applications global addressing of individual IP-WSN nodes and layer-three routing for mobility enabled IP-WSN with special attention to reliability, energy efficiency and end to end delay minimization are a few of the major issues to be addressed. Most of the routing protocols in WSN are based on layer-two approaches. For reliability and end to end communication enhancement the necessity of layer-three routing for IP-WSNs is generating significant attention among the research community, but due to the hurdle of maintaining routing state and other communication overhead, it was not possible to introduce a layer-three routing protocol for IP-WSNs. To address this issue we propose in this paper a global addressing scheme and layer-three based hierarchical routing protocol. The proposed addressing and routing approach focuses on all the above mentioned issues. Simulation results show that the proposed addressing and routing approach significantly enhances the reliability, energy efficiency and end to end delay minimization. We also present architecture, message formats and different routing scenarios in this paper.

A novel addressing scheme for PMIPv6 based global IP-WSNs.

Science.gov (United States)

Islam, Md Motaharul; Huh, Eui-Nam

2011-01-01

IP based Wireless Sensor Networks (IP-WSNs) are being used in healthcare, home automation, industrial control and agricultural monitoring. In most of these applications global addressing of individual IP-WSN nodes and layer-three routing for mobility enabled IP-WSN with special attention to reliability, energy efficiency and end to end delay minimization are a few of the major issues to be addressed. Most of the routing protocols in WSN are based on layer-two approaches. For reliability and end to end communication enhancement the necessity of layer-three routing for IP-WSNs is generating significant attention among the research community, but due to the hurdle of maintaining routing state and other communication overhead, it was not possible to introduce a layer-three routing protocol for IP-WSNs. To address this issue we propose in this paper a global addressing scheme and layer-three based hierarchical routing protocol. The proposed addressing and routing approach focuses on all the above mentioned issues. Simulation results show that the proposed addressing and routing approach significantly enhances the reliability, energy efficiency and end to end delay minimization. We also present architecture, message formats and different routing scenarios in this paper.

Review Report on the Design of In-Pile Test Section(IPS)

International Nuclear Information System (INIS)

Lee, Jong Min; Park, Kook Nam; Shim, Bong Sik; Lee, Chung Young; Chi, Dae Young; Park, Su Ki; Ahn, Sung Ho; Kim, Young Ki; Lee, Kye Hong; Kim, Kwan Hyun

2009-01-01

The In-Pile Test Section(IPS) accommodating fuel pins has loaded IR-1 hole in HANARO has double pressure vessel for the design conditions of 350 deg. C, 17.5 MPa and is composed of outer assembly and inner assembly. Dummy fuel, dummy fuel supports and Top flange are the main components in inner assembly and inner pressure vessel, outer pressure vessel and head are the components in outer assembly. The IPS at current status has dummy fuels and confirm the requirements for the IPS design improvements during the design, manufacturing and installation process. Head, Top Flange, Instrumentation Feed through, Lifting Eye, Fuel Carrier Leg, Retainer and Nozzle cover are the main parts that the design needs to be changed. This report suggest the needs for the IPS design modification and it would be reflected to the new IPS design which would accommodating test fuel pins

Review Report on the Design of In-Pile Test Section(IPS)

Energy Technology Data Exchange (ETDEWEB)

Lee, Jong Min; Park, Kook Nam; Shim, Bong Sik; Lee, Chung Young; Chi, Dae Young; Park, Su Ki; Ahn, Sung Ho; Kim, Young Ki; Lee, Kye Hong; Kim, Kwan Hyun

2009-01-15

The In-Pile Test Section(IPS) accommodating fuel pins has loaded IR-1 hole in HANARO has double pressure vessel for the design conditions of 350 deg. C, 17.5 MPa and is composed of outer assembly and inner assembly. Dummy fuel, dummy fuel supports and Top flange are the main components in inner assembly and inner pressure vessel, outer pressure vessel and head are the components in outer assembly. The IPS at current status has dummy fuels and confirm the requirements for the IPS design improvements during the design, manufacturing and installation process. Head, Top Flange, Instrumentation Feed through, Lifting Eye, Fuel Carrier Leg, Retainer and Nozzle cover are the main parts that the design needs to be changed. This report suggest the needs for the IPS design modification and it would be reflected to the new IPS design which would accommodating test fuel pins.

Aspects of the epidemiology of intestinal parasitosis (IP) in children ...

African Journals Online (AJOL)

Aspects of the epidemiology of intestinal parasitosis (IP) in children: ... Conclusion: The low level of knowledge, practices and perceptions of mothers concerning IP is a major cause for ... EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT

Perspectivas sobre la comunicación

Directory of Open Access Journals (Sweden)

María Luisa Naranjo Pereira

2005-01-01

Full Text Available Existen diversas teorías, enfoques y modelos de comunicación; de cada uno de ellos pueden rescatarse aspectos de gran valor para el logro de una comunicación eficaz. Este documento presenta una revisión de esos aspectos, para que se pueda comprender mejor y enriquecer uno de los procesos más importantes para el ser humano: el proceso de comunicación. Este es un ensayo en el cual se da a conocer la posición de la autora sobre el tema abordado. Se rescata el acento del enfoque humanista en la relación humana y en las etapas donde se desarrolla. A partir de la comunicación pragmática, se analizan los axiomas comunicacionales en que se fundamenta y lo que se conoce como patologías de esos axiomas. Además se revisan las principales características que distinguen la asertividad en la comunicación y las distintas formas de manipulación que la entorpecen. Del enfoque de Virginia Satir, se presentan los diversos aspectos de la comunicación, tanto funcional como disfuncional y los modelos de comunicación propuestos por esta autora. Se revisan aspectos importantes del enfoque de la comunicación educativa, tales como el control de la distancia, la voz y el cuerpo, las palabras y el situacional; así como los elementos que bloquean el proceso de comunicación y las sugerencias acerca de formas correctas de escuchar. Además, se hace referencia a la necesidad de emplear procesos educativos más holísticos y constructivistas y una comunicación-interrelación horizontal y con equidad.

76 FR 81955 - Assessment Questionnaire-IP Sector Specific Agency Risk Self Assessment Tool (IP-SSARSAT)

Science.gov (United States)

2011-12-29

... DEPARTMENT OF HOMELAND SECURITY [Docket No. DHS-2011-0069] Assessment Questionnaire--IP Sector... will be posted without alteration at http://www.regulations.gov , including any personal information... managers often volunteer to conduct an automated self risk assessment. The requested questionnaire...

Searching CLEF-IP by Strategy

NARCIS (Netherlands)

W. Alink (Wouter); R. Cornacchia (Roberto); A.P. de Vries (Arjen)

2010-01-01

htmlabstractTasks performed by intellectual property specialists are often ad hoc, and continuously require new approaches to search a collection of documents. We therefore investigate the benets of a visual `search strategy builder' to allow IP search experts to express their approach to

Single-tube linear DNA amplification (LinDA) for robust ChIP-seq

NARCIS (Netherlands)

Shankaranarayanan, P.; Mendoza-Parra, M.A.; Walia, M.; Wang, L.; Li, N.; Trindade, L.M.; Gronemeyer, H.

2011-01-01

Genome-wide profiling of transcription factors based on massive parallel sequencing of immunoprecipitated chromatin (ChIP-seq) requires nanogram amounts of DNA. Here we describe a high-fidelity, single-tube linear DNA amplification method (LinDA) for ChIP-seq and reChIP-seq with picogram DNA amounts

A Novel Smart Meter Controlling System with Dynamic IP Addresses

DEFF Research Database (Denmark)

Manembu, Pinrolinvic; Welang, Brammy; Kalua Lapu, Aditya

2017-01-01

Smart meters are the electronic devices for measuring energy consumption in real time. Usually, static public IP addresses are allocated to realize the point-to-point (P2P) communication and remote controlling for smart metering systems. This, however, restricts the wide deployment of smart meters......, due to the deficiency of public IP resources. This paper proposes a novel subscription-based communication architecture for the support of dynamic IP addresses and group controlling of smart meters. The paper evaluates the proposed architecture by comparing the traditional P2P architecture...

OSI and TCP/IP

Science.gov (United States)

Randolph, Lynwood P.

1994-01-01

The Open Systems Interconnection Transmission Control Protocol/Internet Protocol (OSI TCP/IP) and the Government Open Systems Interconnection Profile (GOSIP) are compared and described in terms of Federal internetworking. The organization and functions of the Federal Internetworking Requirements Panel (FIRP) are discussed and the panel's conclusions and recommendations with respect to the standards and implementation of the National Information Infrastructure (NII) are presented.

Quantitative ChIP-Seq Normalization Reveals Global Modulation of the Epigenome

Directory of Open Access Journals (Sweden)

David A. Orlando

2014-11-01

Full Text Available Epigenomic profiling by chromatin immunoprecipitation coupled with massively parallel DNA sequencing (ChIP-seq is a prevailing methodology used to investigate chromatin-based regulation in biological systems such as human disease, but the lack of an empirical methodology to enable normalization among experiments has limited the precision and usefulness of this technique. Here, we describe a method called ChIP with reference exogenous genome (ChIP-Rx that allows one to perform genome-wide quantitative comparisons of histone modification status across cell populations using defined quantities of a reference epigenome. ChIP-Rx enables the discovery and quantification of dynamic epigenomic profiles across mammalian cells that would otherwise remain hidden using traditional normalization methods. We demonstrate the utility of this method for measuring epigenomic changes following chemical perturbations and show how reference normalization of ChIP-seq experiments enables the discovery of disease-relevant changes in histone modification occupancy.

Real-time services in IP network architectures

Science.gov (United States)

Gilardi, Antonella

1996-12-01

The worldwide internet system seems to be the success key for the provision of real time multimedia services to both residential and business users and someone says that in such a way broadband networks will have a reason to exist. This new class of applications that use multiple media (voice, video and data) impose constraints to the global network nowadays consisting of subnets with various data links. The attention will be focused on the interconnection of IP non ATM and ATM networks. IETF and ATM forum are currently involved in the developing specifications suited to adapt the connectionless IP protocol to the connection oriented ATM protocol. First of all the link between the ATM and the IP service model has to be set in order to match the QoS and traffic requirements defined in the relative environment. A further significant topic is represented by the mapping of IP resource reservation model onto the ATM signalling and in the end it is necessary to define how the routing works when there are QoS parameters associated. This paper, considering only unicast applications, will examine the above issues taking as a starting point the situation where an host launches as call set up request with the relevant QoS and traffic descriptor and at some point a router at the edge of the ATM network has to decide how forwarding and request in order to establish an end to end link with the right capabilities. The aim is to compare the proposals emerging from different standard bodies to point out convergency or incompatibility.

The Incredibly Long-Lived SN 2005ip

Science.gov (United States)

Fox, Ori

2016-10-01

Type IIn supernovae (SNe IIn) are defined by their relatively narrow spectral line features associated with a dense circumstellar medium (CSM) formed by the progenitor star. The nature of the progenitor and mass loss remains relatively unknown. Shock interaction with the dense CSM can often result in significant UV emission for several years post-explosion, thereby probing the CSM characteristics, progenitor mass loss history and, ultimately, the progenitor itself. The Type IIn SN 2005ip proves to be one of the most interesting and well-studied targets within this subclass. Compared to all other supernovae, SN 2005ip is the most luminous for its age. Now more than 11 years post-explosion, the SN has released >10^51 erg throughout its lifetime as the forward shock continues to collide with a dense CSM. Here we propose HST/STIS-MAMA UV observations of SN 2005ip to investigate the massive CSM. When accounting for the shock travel time, these observations will probe material lost from the progenitor more than 1000 years prior to the explosion. We already have a single HST/STIS spectrum of SN 2005ip from 2014, which was obtained while the shock was still within a higher mass regime. With just 5 orbits, a second spectrum will allow us to directly trace the evolution of the CSM and produce new constraints on the pre-SN mass-loss history. Coinciding with Cycle 24's UV Initiative, this program offers new insight regarding both the progenitor and explosion characteristics of the SN IIn subclass.

Sate-of-the-art IP switching router architecture using SFQ technology

International Nuclear Information System (INIS)

Miyaho, N.; Miyahara, K.; Yamazaki, A.

2006-01-01

Taking the recent trend of rapid IP traffic increasing and QoS in the Internet into account, we propose an innovative IP router architecture from the viewpoint of minimum switching delay, switching capacity, QoS assurance for the next generation Internet services. We examined the IP router performance using superconductivity device simulator (WinS) assuming the future-generation Nb junction process and confirmed more than 300 GHz clock operation. For the evaluation of a novel IP switch architecture, we effectively apply the SFQ circuits using Josephson junctions to an extremely restricted function block in the switching node and a conventional semiconductor technology is also applied for the rest parts of the other function blocks inside it

LMIP/AAA: Local Authentication, Authorization and Accounting (AAA) Protocol for Mobile IP

Science.gov (United States)

Chenait, Manel

Mobile IP represents a simple and scalable global mobility solution. However, it inhibits various vulnerabilities to malicious attacks and, therefore, requires the integration of appropriate security services. In this paper, we discuss two authentication schemes suggested for Mobile IP: standard authentication and Mobile IP/AAA authentication. In order to provide Mobile IP roaming services including identity verication, we propose an improvement to Mobile/AAA authentication scheme by applying a local politic key management in each domain, hence we reduce hando latency by avoiding the involvement of AAA infrastructure during mobile node roaming.

IPS observation system for the Miyun 50 m radio telescope and its commissioning observation

International Nuclear Information System (INIS)

Zhu Xinying; Zhang Xizhen; Zhang Hongbo; Kong Deqing; Qu Huipeng

2012-01-01

Ground-based observation of Interplanetary Scintillation (IPS) is an important approach for monitoring solar wind. A ground-based IPS observation system has been newly implemented on a 50 m radio telescope at Miyun station, managed by the National Astronomical Observatories, Chinese Academy of Sciences. This observation system has been constructed for the purpose of observing solar wind speed and the associated scintillation index by using the normalized cross-spectrum of a simultaneous dual-frequency IPS measurement. The system consists of a universal dual-frequency front-end and a dual-channel multi-function back-end specially designed for IPS. After careful calibration and testing, IPS observations on source 3C 273B and 3C 279 have been successfully carried out. The preliminary observation results show that this newly-developed observation system is capable of performing IPS observation. The system's sensitivity for IPS observation can reach over 0.3 Jy in terms of an IPS polarization correlator with 4 MHz bandwidth and 2 s integration time. (research papers)

Controlling applied to information processing: quality management applied to IP projects and IP services; Informationsverarbeitungs-Controlling: Qualitaetsmanagement fuer IV-Projekte und fuer IV-Service

Energy Technology Data Exchange (ETDEWEB)

Becker, B. [Vereinigung Deutscher Elektrizitaetswerke e.V. (VDEW), Frankfurt am Main (Germany); Beckers, F. [Isar-Amperwerke AG, Muenchen (Germany); Dewald, N. [Bayernwerk AG, Muenchen (Germany); Hauffe, P. [Pfalzwerke AG, Ludwigshafen am Rhein (Germany); Hein, F. [EVS AG Stuttgart (Germany); Hoederath, M. [Vereinigte Elektrizitaetswerke Westfalen AG (VEW), Dortmund (Germany); Seyen, R. [Staedtische Werke Nuernberg GmbH (Germany)

1998-01-12

The working group on information processing (IP) basics (in German: `IV-Grundlagen`) has prepared this contribution dealing with controlling applied to information processing. This new report, on the one hand, takes into consideration the role of the organizational IP unit as one offering its services to all sections of a company. On the other hand, information processing as an operational infrastructure influencing all business processes becomes increasingly important with respect to the competitiveness of the EVU. Therefore, quality management applied to IP projects and IP services must support this development. (orig./RHM) [Deutsch] Der VDEW Arbeitskreis `IV-Grundlagen` hat einen Beitrag zum Controlling fuer die Informationsverarbeitung erstellt. Hier geht zum einen die Rolle der Organisationseinheit IV als Dienstleister fuer alle Unternehmensbereiche ein. Zum anderen gewinnt die Informationsverarbeitung als betriebliche Infrastruktur fuer alle Geschaeftsprozesse zunehmende Bedeutung fuer die Wettbewerbsfaehigkeit der EVU. Das Qualitaetsmanagement fuer IV-Projekte und fuer IV-Service muss dies unterstuetzen. (orig./RHM)

Diseño del Sistema Integral de Medicion de Gestion (SIMEG de la IPS del Instituto de Seguros Sociales

Directory of Open Access Journals (Sweden)

Paula Bernal Gelvis

2000-12-01

Full Text Available Este articulo presenta los resultados obtenidos en la monografia "Diserio del Sistema Integral de Medici6n de la Gestión (SIMEG en la Institución prestadora de servicios (IPS del Instituto de Seguros Sociales (ISS"; en la que -utilizando la inferencia deductiva-, se plantea el SIMEG como una herramienta administrativa para la evaluación y el monitoreo de la gestión. Para el diseño de esta herramienta, en primera instancia se realiza un acercamiento teórico a la metodología recurriendo a diversas fuentes bibliográficas (Iibros, artículos, publicaciones en Internet, panelistas, seminarios, etc. para determinar el estado del arte del Balanced Scorecard y las metodologías analoqas tales como el SIMEG; y en segundo lugar, se construye un marco conceptual sobre el objeto de estudio, la Institución prestadora de servicios (IPS del ISS, a través del establecimiento del marco legal, el análisis situacional y la recolección de información interna (administrativa, estratégica. presupuestal, financiera, contable, estadistica, etc.. De esta manera se logra una aproximaci6n te6rica al Sistema integral de medición de la gestión, SIMEG, que proporcione las herramientas necesarias para comprender la magnitud y el alcance de la metodología que se pretende implementar. Finalmente se describe paso a paso el proceso metodológico utilizado en su implantación en la IPS del ISS y, por ultimo, se plantean sugerencias con el objeto de asegurar el éxito en dicho proceso.

Practical guidelines for the comprehensive analysis of ChIP-seq data.

Directory of Open Access Journals (Sweden)

Timothy Bailey

Full Text Available Mapping the chromosomal locations of transcription factors, nucleosomes, histone modifications, chromatin remodeling enzymes, chaperones, and polymerases is one of the key tasks of modern biology, as evidenced by the Encyclopedia of DNA Elements (ENCODE Project. To this end, chromatin immunoprecipitation followed by high-throughput sequencing (ChIP-seq is the standard methodology. Mapping such protein-DNA interactions in vivo using ChIP-seq presents multiple challenges not only in sample preparation and sequencing but also for computational analysis. Here, we present step-by-step guidelines for the computational analysis of ChIP-seq data. We address all the major steps in the analysis of ChIP-seq data: sequencing depth selection, quality checking, mapping, data normalization, assessment of reproducibility, peak calling, differential binding analysis, controlling the false discovery rate, peak annotation, visualization, and motif analysis. At each step in our guidelines we discuss some of the software tools most frequently used. We also highlight the challenges and problems associated with each step in ChIP-seq data analysis. We present a concise workflow for the analysis of ChIP-seq data in Figure 1 that complements and expands on the recommendations of the ENCODE and modENCODE projects. Each step in the workflow is described in detail in the following sections.

The extended TRIP supporting VoIP routing reservation with distributed QoS

Science.gov (United States)

Wang, Furong; Wu, Ye

2004-04-01

In this paper, an existing protocol, i.e. TRIP (Telephony Routing over IP) is developed to provide distributed QoS when making resource reservations for VoIP services such as H.323, SIP. Enhanced LSs (location servers) are deployed in ITADs (IP Telephony Administrative Domains) to take in charge of intra-domain routing policy because of small propagation price. It is an easy way to find an IP telephone route for intra-domain VoIP media association and simultaneously possess intra-domain load balancing features. For those routing reservations bridging domains, inter-domain routing policy is responsible for finding the shortest inter-domain route with enough resources. I propose the routing preference policy based on QoS price when the session traffic is shaped by a token bucket, related QoS messages, and message cooperation.

IP cores design from specifications to production modeling, verification, optimization, and protection

CERN Document Server

Mohamed, Khaled Salah

2016-01-01

This book describes the life cycle process of IP cores, from specification to production, including IP modeling, verification, optimization, and protection. Various trade-offs in the design process are discussed, including  those associated with many of the most common memory cores, controller IPs  and system-on-chip (SoC) buses. Readers will also benefit from the author’s practical coverage of new verification methodologies. such as bug localization, UVM, and scan-chain.  A SoC case study is presented to compare traditional verification with the new verification methodologies. ·         Discusses the entire life cycle process of IP cores, from specification to production, including IP modeling, verification, optimization, and protection; ·         Introduce a deep introduction for Verilog for both implementation and verification point of view.  ·         Demonstrates how to use IP in applications such as memory controllers and SoC buses. ·         Describes a new ver...

Longevity and clinical performance of IPS-Empress ceramic restorations--a literature review.

Science.gov (United States)

El-Mowafy, Omar; Brochu, Jean-François

2002-04-01

A literature review of longevity and clinical performance of IPS-Empress restorations is presented. A MEDLINE search was conducted in fall 2000. Selection criteria were set so as to identify suitable clinical trials that were published in full and that had lasted more than 2 years. A total of 6 clinical trials on the performance of IPS-Empress inlays and onlays and a total of 3 clinical trials on the performance of IPS-Empress crowns were identified. Survival rates for IPS-Empress inlays and onlays ranged from 96% at 4.5 years to 91% at 7 years; most failures were due to bulk fracture. IPS-Empress crowns had a survival rate ranging from 92% to 99% at 3 to 3.5 years; crown failure was also mainly due to fracture. Dentists should inform their patients about these survival rates when offering such treatment. The use of IPS-Empress crowns in the posterior of the mouth is not recommended until the results of more long-term clinical trials are available.

Data exploration, quality control and statistical analysis of ChIP-exo/nexus experiments.

Science.gov (United States)

Welch, Rene; Chung, Dongjun; Grass, Jeffrey; Landick, Robert; Keles, Sündüz

2017-09-06

ChIP-exo/nexus experiments rely on innovative modifications of the commonly used ChIP-seq protocol for high resolution mapping of transcription factor binding sites. Although many aspects of the ChIP-exo data analysis are similar to those of ChIP-seq, these high throughput experiments pose a number of unique quality control and analysis challenges. We develop a novel statistical quality control pipeline and accompanying R/Bioconductor package, ChIPexoQual, to enable exploration and analysis of ChIP-exo and related experiments. ChIPexoQual evaluates a number of key issues including strand imbalance, library complexity, and signal enrichment of data. Assessment of these features are facilitated through diagnostic plots and summary statistics computed over regions of the genome with varying levels of coverage. We evaluated our QC pipeline with both large collections of public ChIP-exo/nexus data and multiple, new ChIP-exo datasets from Escherichia coli. ChIPexoQual analysis of these datasets resulted in guidelines for using these QC metrics across a wide range of sequencing depths and provided further insights for modelling ChIP-exo data. © The Author(s) 2017. Published by Oxford University Press on behalf of Nucleic Acids Research.

Briefer assessment of social network drinking: A test of the Important People Instrument-5 (IP-5).

Science.gov (United States)

Hallgren, Kevin A; Barnett, Nancy P

2016-12-01

The Important People instrument (IP; Longabaugh et al., 2010) is one of the most commonly used measures of social network drinking. Although its reliability and validity are well-supported, the length of the instrument may limit its use in many settings. The present study evaluated whether a briefer, 5-person version of the IP (IP-5) adequately reproduces scores from the full IP. College freshmen (N = 1,053) reported their own past-month drinking, alcohol-related consequences, and information about drinking in their close social networks at baseline and 1 year later. From this we derived network members' drinking frequency, percentage of drinkers, and percentage of heavy drinkers, assessed for up to 10 (full IP) or 5 (IP-5) network members. We first modeled the expected concordance between full-IP scores and scores from simulated shorter IP instruments by sampling smaller subsets of network members from full IP data. Then, using quasi-experimental methods, we administered the full IP and IP-5 and compared the 2 instruments' score distributions and concurrent and year-lagged associations with participants' alcohol consumption and consequences. Most of the full-IP variance was reproduced from simulated shorter versions of the IP (ICCs ≥ 0.80). The full IP and IP-5 yielded similar score distributions, concurrent associations with drinking (r = 0.22 to 0.52), and year-lagged associations with drinking. The IP-5 retains most of the information about social network drinking from the full IP. The shorter instrument may be useful in clinical and research settings that require frequent measure administration, yielding greater temporal resolution for monitoring social network drinking. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

Real-time resource availability signaling in IP multimedia subsystem networks

NARCIS (Netherlands)

Ozcelebi, T.; Radovanovic, I.; Sengupta, D.

2008-01-01

IP Multimedia Subsystem (IMS) allows the use of unlicensed, non-dedicated and nondeterministic access networks for delivering IP multimedia services. Providing end-to-end Quality-of-Service (QoS) for resource demanding real-time services (e.g. real-time multimedia) over such networks is a

Web-based IP telephony penetration system evaluating level of protection from attacks and threats

OpenAIRE

Vozňák, Miroslav; Řezáč, Filip

2011-01-01

This article deals with detection of threats in IP telephony, the authors developed a penetration testing system that is able to check up the level of protection from security threats in IP telephony. SIP is being widely used in building VoIP networks. Unlike the traditional telephone networks VoIP networks does not have a closed communication which makes communication medium vulnerable to all kinds of attacks from the in truders. The SIP server is a key component of VoIP infrastr...

Implementasi Server VoIP Berbasis SIP Pada LAN Nirkabel

Directory of Open Access Journals (Sweden)

Mohammad Shoffa Al Arofat

2013-03-01

Full Text Available Voice over Internet Protocol (VoIP merupakan teknologi yang memungkinkan percakapan suara jarak jauh melalui protokol internet. Dalam telekomunikasi, diperlukan teknologi pensinyalan yang berguna untuk membangun, mengawasi, dan melepas hubungan antara dua titik. Salah satu teknologi pensinyalan yang banyak digunakan untuk VoIP adalah Session Initiation Protocol, dengan implementasinya yang berupa perangkat lunak Open SIP Server. Selain pensinyalan, ada beberapa parameter yang perlu diperhatikan dalam implementasi VoIP, yaitu Mean Opinion Score (MOS, network impairment, dan bandwidth. Pengujian dilakukan terhadap enam codec, yaitu G.722, PCMA, PCMU, Speex, GSM, dan BV16. Berdasarkan hasil analisis dapat diambil kesimpulan bahwa codec yang menggunakan bandwidth paling rendah adalah Speex (27,12 kbps; Rata-rata delay yang dihasilkan oleh sipdroid lebih baik daripada jitsi.

Examples of modelling IP in AEM data: synthetic and real data

DEFF Research Database (Denmark)

Viezzoli, Andrea; Kaminskiy, Vladislav; Fiandaca, Gianluca

There have been multiple evidences in the literature in the past several years of what has been referred to as IP effect in the Time Domain Airborne EM data (TDEM). This phenomenon is known to be responsible for incorrect inversion modelling of electrical resistivity, lower interpreted depth...... of investigation and lost information about chargeability of the subsurface as well as about other valuable parameters. Historically there have been many suggestions to account for the IP effect using the Cole-Cole model. In current paper we are showing the possibility to extract IP information from airborne TDEM...... with both high electrical conductivity and in resistive environments. Furthermore, modelling of IP effects allows corrected resistivity models. The Amakinskaya kimberlite pipe results highlight the relevance of chargeability for kimberlite exploration....

Analisis Kualitas VoIP pada SCTP Menggunakan ECN dan AQM

Directory of Open Access Journals (Sweden)

La Surimi

2015-07-01

Abstract VoIP is the real time applications that are highly dependent on the quality of  delay and jitter, which it is difficult to be met by protocol that has reliable data transfer feature and  congestion control such as TCP. On the other hand the use of UDP that has no congestion control make chance of causing congestion in the network is very large. The use of SCTP as an alternative protocol was also not able to accommodate the weaknesses of TCP and UDP. Some research shows that repairs or modifications to the SCTP congestion control mechanism is needed. The Use of ECN and AQM in some studies show that these two mechanisms can reduce delay and jitter. This study tested the quality of VoIP over SCTP with ECN and AVQ, in NS2. Simulations carried out by independent replication technique, and the results showed that ECN and AVQ can increase the value of MOS VoIP calls significantly in non ideal network scenarios. This study also did comparison of SCTP MOS that uses ECN and AVQ with MOS values VoIP using TCP and UDP. The result showed that SCTP with ECN and AVQ outperform TCP but can not surpass UDP yet.   Keywords— VoIP, SCTP, ECN, AQM,AVQ.

VoIP interconnection ; between Internet, Cable, Mobile and Fixed Worlds

NARCIS (Netherlands)

Deventer, M.O. van; Keesmaat, I.

2005-01-01

Four worlds on their own that hardly interconnect; All use SIP, but differently - Internet world - Mobile world - Cable world - Fixed world - At most, only basic voice service will interoperate between those worlds In recent years, VoIP/multimedia services (VoIP: Voice over Internet Protocol) have

Protecting LHC IP1/IP5 Components Against Radiation Resulting from Colliding Beam Interactions

CERN Document Server

Mokhov, N V; Kerby, J S; Strait, J B

2003-01-01

Beam-induced energy deposition in the LHC high luminosity interaction region (IR) components due to both pp collisions and beam loss in the IR vicinity is a significant challenge for the design of the high luminosity insertions. It was shown in our previous studies that a set of absorbers would reduce both the peak power density and total heat load to tolerable levels. In this paper the results of further optimization and comprehensive MARS calculations are summarized for the LHC lattice, version 6.4, for the updated IP1 and IP5 layouts and a baseline pp-collision source term. Power density, power dissipation, particle fluxes and spectra, accumulated dose and residual dose rates are studied in the components of the inner triplets including their TAS absorbers, the TAN neutral beam absorbers, separation dipoles, and quadrupoles of the outer triplets and possible collimators there. Results are given for the nominal luminosity of 1034 cm-2 s-1. The current design is proved to provide the best safety margin under...

Analysis of ChIP-seq Data in R/Bioconductor.

Science.gov (United States)

de Santiago, Ines; Carroll, Thomas

2018-01-01

The development of novel high-throughput sequencing methods for ChIP (chromatin immunoprecipitation) has provided a very powerful tool to study gene regulation in multiple conditions at unprecedented resolution and scale. Proactive quality-control and appropriate data analysis techniques are of critical importance to extract the most meaningful results from the data. Over the last years, an array of R/Bioconductor tools has been developed allowing researchers to process and analyze ChIP-seq data. This chapter provides an overview of the methods available to analyze ChIP-seq data based primarily on software packages from the open-source Bioconductor project. Protocols described in this chapter cover basic steps including data alignment, peak calling, quality control and data visualization, as well as more complex methods such as the identification of differentially bound regions and functional analyses to annotate regulatory regions. The steps in the data analysis process were demonstrated on publicly available data sets and will serve as a demonstration of the computational procedures routinely used for the analysis of ChIP-seq data in R/Bioconductor, from which readers can construct their own analysis pipelines.

A Learning-Based Approach for IP Geolocation

Science.gov (United States)

Eriksson, Brian; Barford, Paul; Sommers, Joel; Nowak, Robert

The ability to pinpoint the geographic location of IP hosts is compelling for applications such as on-line advertising and network attack diagnosis. While prior methods can accurately identify the location of hosts in some regions of the Internet, they produce erroneous results when the delay or topology measurement on which they are based is limited. The hypothesis of our work is that the accuracy of IP geolocation can be improved through the creation of a flexible analytic framework that accommodates different types of geolocation information. In this paper, we describe a new framework for IP geolocation that reduces to a machine-learning classification problem. Our methodology considers a set of lightweight measurements from a set of known monitors to a target, and then classifies the location of that target based on the most probable geographic region given probability densities learned from a training set. For this study, we employ a Naive Bayes framework that has low computational complexity and enables additional environmental information to be easily added to enhance the classification process. To demonstrate the feasibility and accuracy of our approach, we test IP geolocation on over 16,000 routers given ping measurements from 78 monitors with known geographic placement. Our results show that the simple application of our method improves geolocation accuracy for over 96% of the nodes identified in our data set, with on average accuracy 70 miles closer to the true geographic location versus prior constraint-based geolocation. These results highlight the promise of our method and indicate how future expansion of the classifier can lead to further improvements in geolocation accuracy.

POLÍTICAS PÚBLICAS E A VOZ DAS CRIANÇAS

Directory of Open Access Journals (Sweden)

Silvia Helena Vieira Cruz

2017-04-01

Full Text Available O artigo parte dos pressupostos de que as crianças têm direito e são competentes para falar sobre as suas experiências e de que conhecer suas perspectivas sobre suas experiências educacionais enriquece e amplia o nosso conhecimento sobre elas. As falas produzidas em várias pesquisas que ouviram crianças no Brasil informam, dentre muitas outras coisas que: fazer amigos e brincar é o que mais apreciam; uma alimentação saborosa é muito importante; a boa professora é sensível às suas demandas e não grita nem castiga; não gostam das tarefas que lhes tomam tanto tempo da rotina; e, no caso das crianças negras, enfrentam problemas para construir uma boa imagem de si. São indicações fundamentais para políticas voltadas a essa etapa da educação, como políticas de formação inicial e continuada de professores, de currículo, de construção e reforma de prédios escolares, aquisição de brinquedos e livros infantis.

Optimal use of tandem biotin and V5 tags in ChIP assays

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Krpic Sanja

2009-02-01

Full Text Available Abstract Background Chromatin immunoprecipitation (ChIP assays coupled to genome arrays (Chip-on-chip or massive parallel sequencing (ChIP-seq lead to the genome wide identification of binding sites of chromatin associated proteins. However, the highly variable quality of antibodies and the availability of epitopes in crosslinked chromatin can compromise genomic ChIP outcomes. Epitope tags have often been used as more reliable alternatives. In addition, we have employed protein in vivo biotinylation tagging as a very high affinity alternative to antibodies. In this paper we describe the optimization of biotinylation tagging for ChIP and its coupling to a known epitope tag in providing a reliable and efficient alternative to antibodies. Results Using the biotin tagged erythroid transcription factor GATA-1 as example, we describe several optimization steps for the application of the high affinity biotin streptavidin system in ChIP. We find that the omission of SDS during sonication, the use of fish skin gelatin as blocking agent and choice of streptavidin beads can lead to significantly improved ChIP enrichments and lower background compared to antibodies. We also show that the V5 epitope tag performs equally well under the conditions worked out for streptavidin ChIP and that it may suffer less from the effects of formaldehyde crosslinking. Conclusion The combined use of the very high affinity biotin tag with the less sensitive to crosslinking V5 tag provides for a flexible ChIP platform with potential implications in ChIP sequencing outcomes.

Optimal use of tandem biotin and V5 tags in ChIP assays

Science.gov (United States)

Kolodziej, Katarzyna E; Pourfarzad, Farzin; de Boer, Ernie; Krpic, Sanja; Grosveld, Frank; Strouboulis, John

2009-01-01

Background Chromatin immunoprecipitation (ChIP) assays coupled to genome arrays (Chip-on-chip) or massive parallel sequencing (ChIP-seq) lead to the genome wide identification of binding sites of chromatin associated proteins. However, the highly variable quality of antibodies and the availability of epitopes in crosslinked chromatin can compromise genomic ChIP outcomes. Epitope tags have often been used as more reliable alternatives. In addition, we have employed protein in vivo biotinylation tagging as a very high affinity alternative to antibodies. In this paper we describe the optimization of biotinylation tagging for ChIP and its coupling to a known epitope tag in providing a reliable and efficient alternative to antibodies. Results Using the biotin tagged erythroid transcription factor GATA-1 as example, we describe several optimization steps for the application of the high affinity biotin streptavidin system in ChIP. We find that the omission of SDS during sonication, the use of fish skin gelatin as blocking agent and choice of streptavidin beads can lead to significantly improved ChIP enrichments and lower background compared to antibodies. We also show that the V5 epitope tag performs equally well under the conditions worked out for streptavidin ChIP and that it may suffer less from the effects of formaldehyde crosslinking. Conclusion The combined use of the very high affinity biotin tag with the less sensitive to crosslinking V5 tag provides for a flexible ChIP platform with potential implications in ChIP sequencing outcomes. PMID:19196479

EXPERIENCIAS DE GUERRA DESDE LA VOZ DE LAS MUJERES

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Elsa Blair

2003-01-01

Full Text Available El articulo recoge algunas reflexiones en tormo al trabajode campo realizado con mujeres excombatientes de diversos grupos armados colombianos en el marco de la investigación Mujeres en tiempos de guerra: una mirada a lo femenino en el contexto de los grupos armados colombianos. A partir de una concepción de la guerra como construcción cultural, las autoras interrogan los efectos de la misma sobre su identidad femenina, esto es, lo que la guerra ha representado para ellas como mujeres y los efectos que ha tenido en términos de su identidad genérica. Tras una reflexión inicia en torno a los desafíos éticos planteados por el trabajo de campo, las autoras abordan la problemática de la identidad de género a través de dos vías: por una parte, los campos o "nudos¿ temáticos que amarran las narraciones de mujeres entrevistadas -la familia, la maternidad y los hijos, las relaciones con los "otros", las experiencias de muerte y el dolor de la guerra-; y por otra, la forma particular en que ellas construyen sus relatos sobre su experiencia como combatientes. Por último, a partir de esa mirada analítica sobre la manera como estas mujeres han vivido y significado su experiencia como guerreras, las autoras plantean, algunas conclusiones preliminares en torno a dicha problemática.

Emancipating Intellectual Property from Proprietarianism: Drahos, Foucault, and a Quasi-Genealogy of IP

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Wendyl Luna

2018-01-01

Full Text Available This paper argues that Peter Drahos undertakes a partial Foucauldian genealogy by emancipating intellectual property (IP from proprietarianism. He demonstrates the dominance of proprietarianism in IP by drawing sample practices from trademark, copyright, and patent laws, and then seeks to displace the proprietarian dominance with instrumentalism, which reconstitutes IP as a “liberty-intruding privilege.” Ironically, despite doing a genealogy, Drahos does not eradicate sovereignty altogether as Michel Foucault insists, but instead determines IP as a “sovereignty mechanism” that has a “sovereignty effect.” After explaining what Foucauldian genealogy is, the paper will explain how Drahos undertakes a genealogy of IP, while highlighting the limitations of Drahos’ analysis from a Foucauldian perspective.

IP-10 release assays in the diagnosis of tuberculosis infection

DEFF Research Database (Denmark)

Ruhwald, Morten; Aabye, Martine G; Ravn, Pernille

2012-01-01

The current state-of-the-art tests for infection with Mycobacterium tuberculosis - the IFN-γ release assays - rely on accurate measurement of the cytokine IFN-γ. Many other potential biomarkers are expressed in concert with IFN-γ, and IP-10 in particular has shown promising results. IP-10...

EQuIP-ped for Success

Science.gov (United States)

Ewing, Molly

2015-01-01

The Educators Evaluating the Quality of Instructional Products (EQuIP) Rubric for science is a new tool for science educators that provides criteria by which to examine the alignment and overall quality of lessons and units with respect to the "Next Generation Science Standards" ("NGSS"). The rubric criteria are divided into…

(S)-(+)-Ipsdienol: Interspecific Inhibition of Ips latidens (LeConte) by Ips pini (Say) (Coleoptera: Scolytidae)

Science.gov (United States)

Daniel R. Miller; John H. Borden

1992-01-01

In south-central British Columbia, the attraction of Ips latidens (LeConte) to its pheromone, ipsenol, was inhibited by (S)-(+)-ipsdienol, a pheromone for I. pini (Say). (R)-(-)-Ipsdienol had no effect on I. latidens. (S)-(+)-lpsdienol probably plays a role in interspecific communication between the two species...

Analisis Data Digital Evidence pada Layanan Voice Over Internet Protocol (VoIP

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Muhamad Arsad Adam

2016-11-01

Full Text Available Teknologi  VoIP  (Voice  Over  Internet  Protocol merupakan  teknologi  yang  mampu  melewatkan  panggilan  suara, video  dan  data  dalam  jaringan  IP.  Voice  over  Internet  Protocol (VoIP  dalam  teknologi  komunikasi  cukup  signifikan  sehingga tidak  terlepas  dari  kejahatan  cybercrime,  Teknologi  VoIP  dapat disalahgunakan  untuk  melakukan  tindakan  kejahatan  jarak  jauh sehingga  diperlukan  langkah-langkah  investigasi  jika  terjadi masalah.  Menemukan  artefact  pada  Infrastruktur  VoIP merupakan tantangan tersendiri. WireSharks salah satu tool yang digunakan  dalam  investigasi  ini.  Metode  yang  digunakan  adalah DFIF  yang  terdiri  tahapan  adalah  Collection,  Examination, Analysis, dan Report and Documentation. Investigasi pada layanan VoIP  dapat  berhasil  dilakukan  dengan  menemukan  data  digital evidence  di  layer  5.  Tujuan  Penelitian  ini  yaitu  Mengetahui Karakteristik Data Digital berupa suara pada layanan Voice Over IP  dan  Menganalisis  Data  Digital  berupa  suara  pada  layanan Voice Over IP. Hasil dari penelitian ini barang bukti digital yang berupa  percakapan  yang  dapat  dipertanggungjawabkan  dalam pengadilan..Kata kunci— Data, Evidence, Forensik,Network, VoIP

Influência de doses crescentes de chumbo sobre o teor e o conteúdo de nutrientes e Pb em mudas de ipê-roxo (Tabebuia impetiginosa (Mart. Standl. Influence of increasing lead levels on nutrient and Pb content and accumulation in ipê-roxo (Tabebuia impetiginosa (Mart. Standl. seedlings

Directory of Open Access Journals (Sweden)

Haroldo Nogueira de Paiva

2003-04-01

Full Text Available O efeito da aplicação de chumbo sobre o teor e o conteúdo de nutrientes e Pb na raiz, no caule e nas folhas de mudas de ipê-roxo (Tabebuia impetiginosa (Mart. Standl. foi estudado em um experimento realizado em casa de vegetação do Departamento de Ciência do Solo da Universidade Federal de Lavras. As mudas foram cultivadas em solução nutritiva de Clark e submetidas a doses crescentes de Pb: 0, 48, 96, 192 e 288 mimol/l. O experimento foi conduzido em delineamento estatístico de blocos ao acaso, e após 60 dias de exposição ao metal pesado foram feitas avaliações do teor e do conteúdo de macro, micronutrientes e chumbo na matéria seca de raiz, caule e folha. Os resultados mostraram que a aplicação de chumbo aumentou o teor de P e praticamente não afetou os teores de S, Ca e Mg nas mudas. De modo geral os teores de Cu, Fe e Mn sofreram redução, o teor de Zn não foi afetado, enquanto o conteúdo de macro e de micronutrientes sofreu redução. O teor de Pb na matéria seca de raiz, caule e folha aumentou com as doses aplicadas, principalmente na raiz, e se mostrou pouco móvel nas plantas analisadas.The effect of lead application on nutrient and Pb content and accumulation in ipê-roxo (Tabebuia impetiginosa (Mart. Standl. seedlings was studied in an experiment conducted under greenhouse conditions at the Soil Science Department of the Federal University of Lavras. The seedlings were cultivated in Clark nutrient solution and submitted to increasing Pb levels: 0, 48, 96, 192 and 288 mumol/l. The experiment was arranged in a randomized block design and after 60 days of exposure to the heavy metals, evaluations of macro and micronutrient and lead content and accumulation in the root, stem and leaf dry matter were made. The results showed that lead application increased P content and practically did not affect S, Ca and Mg contents. Cu, Fe and Mn contents, in general, presented a reduction; Zn content was not affected while macro

Impact of time-domain IP pulse length on measured data and inverted models

DEFF Research Database (Denmark)

Olsson, P. I.; Fiandaca, G.; Dahlin, T.

2015-01-01

The duration of time domain (TD) induced polarization (IP) current injections has significant impact on the acquired IP data as well as on the inversion models, if the standard evaluation procedure is followed. However, it is still possible to retrieve similar inversion models if the waveform...... of the injected current and the IP response waveform are included in the inversion. The on-time also generally affects the signal-tonoise ratio (SNR) where an increased on-time gives higher SNR for the IP data....

A Brazilian version of the "Children's Interview for Psychiatric Syndromes" (ChIPS A versão brasileira do "Children's Interview for Psychiatric Syndromes" (ChIPS

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Isabella G. S. de Souza

2009-01-01

Full Text Available OBJETIVE: The advance of research in child and adolescent psychiatry in Brazil heavily depends on the existence of instruments for the investigation of psychiatric syndromes adapted to Brazilian Portuguese. METHODS: This article describes a careful process of translation of the Children's Interview for Psychiatric Syndromes for the purpose of use in research in Brazil. The Children's Interview for Psychiatric Syndromes has a version for parents (P-ChIPs and a version for children (ChIPS. In this article, the sections of P-ChIPS referring to attention-deficit hyperactivity disorder, oppositional-defiant disorder, conduct disorder, mania/hypomania, anorexia nervosa, bulimia nervosa and psychotic disorders were translated to Brazilian Portuguese. The sections of the ChIPS referring to substance use disorders, social anxiety disorder, specific phobias, obsessive-compulsive disorder, generalized anxiety disoder, separation anxiety disorder, post-traumatic disorders and depression/dysthimia were also adapted. Each section was translated by two independent translators and later discussed in a committee composed of experts in the field of Psychiatry and a professional of the field of linguistics. RESULT: A final version containing an interview for the main psychiatric syndromes was defined. CONCLUSION: The translated P-ChIPS is a helpful instrument in children and adolescent clinical evaluation.OBJETIVO: O avanço em pesquisa em psiquiatria da infância e adolescência no Brasil depende da existência de instrumentos para a investigação de síndromes psiquiátricas adaptadas à Língua Portuguesa. Este artigo descreve um cuidadoso processo de tradução do Children´s Interview for Psychiatric Syndromes para o uso em pesquisa no Brasil. MÉTODOS: O Children´s Interview for Psychiatric Syndromes tem uma versão para pais (P-ChIPs e uma versão para as crianças (ChIPs. Nesse artigo, as seções do P-ChIPs referentes ao transtorno do déficit de aten

Personality characteristics of Serbian male wheelchair and professional basketball players [Charakteristika osobnosti srbských basketbalistů-vozíčkářů a profesionálních basketbalistů

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Fadilj Eminović

2012-06-01

.[VÝCHODISKA: Sport jak sociální fenomén může mít velmi pozitivní vliv na zdraví a sociální situaci osob s postižením, které jej provozují. Velmi důležité místo mezi aktivitami postižených sportovců mohou zaujímat kolektivní sporty. CÍLE: Studie měla tyto cíle – a prošetřit charakteristiku osobnosti profesionálních basketbalistů a basketbalistů-vozíčkářů; b porovnat tyto charakteristiky dvou druhů sportovců. METODIKA: Pro účely této studie profesionální basketbalisté (N = 29 a basketbalisté-vozíčkáři (N = 25 vyplnili dotazník Cattell 16PF, v němž jsou ohodnoceny charakteristiky osobnosti. Rozdíly mezi oběma skupinami účastníků byly spočteny pomocí t-testu pro malé vzorky. VÝSLEDKY: Výsledky prokázaly výskyt rozdílů mezi oběma skupinami ve vyjádření určitých forem chování v rámci určitých dimenzí osobnosti. Basketbalisté-vozíčkáři zaznamenali vyšší skóre u faktoru M – roztržitost (t = –1,889; p = 0,046, což znamená, že se více za bývají sami sebou a svým vnitřním duševním stavem. Basketbalisté-vozíčkáři zaznamenali nižší skóre u faktorů C – emocionální stabilita (t = 2,097; p = 0,041, E – dominance (t = 3,530; p = 0,001, F – živost (t = 2,658; p = 0,010 a N – odloučenost (t = 2,527; p = 0,015. ZÁVĚRY: Basketbalisté-vozíčkáři jsou ve srovnání s profesionálními basketbalisty více emocionální; mají nižší sebeúctu, jsou méně připravení na týmovou práci a spolupráci; jsou naivní a skromní. Na základě těchto výsledků musejí trenéři, kteří pracují s basketbalisty-vozíčkáři, přizpůsobit své tréninkové metody, zejména ti trenéři, kteří dříve pracovali s hráči bez postižení. Vliv trenérů může také podnítit eventuální změny v některých z výše uvedených charakteristik basketbalistů-vozíčkářů žádoucím směrem.

Considerations on VoIP Throughput in 802.11 Networks

Directory of Open Access Journals (Sweden)

POTORAC, A. D.

2009-10-01

Full Text Available Voice data packets have to arrive at the destination in time, with a defined cadence and with low and constant delay in order to allow the real time voice reconstruction. From this point of view, transmitting voice over IP networks is the most sensitive category of applications, especially when wireless medium is involved. The paper discusses the possibilities of transmitting the maximum number of simultaneous voice streams over 802.11 wireless networks considering the main factors which impact with VoIP throughput, in a basic scenario. Starting from a proposed communication model, the number of simultaneous possible VoIP sessions is calculated, taking into consideration the contribution of the protocol overheads, the security overheads, the PHY level timings and the CODEC proprieties. Numerical results are generated and compared.

Multiformat decoder for a DSP-based IP set-top box

Science.gov (United States)

Pescador, F.; Garrido, M. J.; Sanz, C.; Juárez, E.; Samper, D.; Antoniello, R.

2007-05-01

Internet Protocol Set-Top Boxes (IP STBs) based on single-processor architectures have been recently introduced in the market. In this paper, the implementation of an MPEG-4 SP/ASP video decoder for a multi-format IP STB based on a TMS320DM641 DSP is presented. An initial decoder for PC platform was fully tested and ported to the DSP. Using this code an optimization process was started achieving a 90% speedup. This process allows real-time MPEG-4 SP/ASP decoding. The MPEG-4 decoder has been integrated in an IP STB and tested in a real environment using DVD movies and TV channels with excellent results.

Threshold-based generic scheme for encrypted and tunneled Voice Flows Detection over IP Networks

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M. Mazhar U. Rathore

2015-07-01

Full Text Available VoIP usage is rapidly growing due to its cost effectiveness, dramatic functionality over the traditional telephone network and its compatibility with public switched telephone network (PSTN. In some countries, like Pakistan, the commercial usage of VoIP is prohibited. Internet service providers (ISPs and telecommunication authorities are interested in detecting VoIP calls to either block or prioritize them. So detection of VoIP calls is important for both types of authorities. Signature-based, port-based, and pattern-based VoIP detection techniques are inefficient due to complex and confidential security and tunneling mechanisms used by VoIP. In this paper, we propose a generic, robust, efficient, and practically implementable statistical analysis-based solution to identify encrypted, non-encrypted, or tunneled VoIP media (voice flows using threshold values of flow statistical parameters. We have made a comparison with existing techniques and evaluated our system with respect to accuracy and efficiency. Our system has 97.54% direct rate and .00015% false positive rate.

PENGGUNAAN METODE SIMULASI DALAM PEMBELAJARAN KETERAMPILAN LITERASI INFORMASI IPS BAGI MAHASISWA PGSD

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Ana Nurhasanah

2016-06-01

Full Text Available Abstrak. Mata pelajaran IPS di Sekolah Dasar dikembangkan sebagai mata pelajaran terintegrasi atau integrative social studies, bukan sebagai pendidikan disiplin ilmu. Tantangan yang dihadapi peserta didik saat ini adalah banyak dan beragamnya masalah-masalah sosial yang harus dihadapi dalam kehidupan sehari-hari, oleh sebab itu pembelajaran IPS bertujuan untuk  mengembangkan keterampilan sosial. Namun, mengingat perkembangan siswa SD yang masih dalam tingkat berpikir kongkrit maka disarankan pembelajaran IPS SD menggunakan contoh-contoh masalah sosial yang kongkrit dan yang  mungkin melibatkan pengalaman-pengalaman siswa SD secara langsung. Namun dalam kenyataannya berdasarkan wawancara pada guru-guru SD di kota Serang masih banyak ditemukan kesulitan dalam mengajarkan IPS. Hal ini menunjukan bahwa kemampuan guru-guru di SD belum sesuai dengan tuntutan tujuan pembelajaran IPS. Oleh sebab itu penting kiranya mahasiswa PGSD semester V sebagai calon tenaga pendidik dibekali pengalaman dengan metode simulasi guna mengembangkan literasi informasi pada pembelajaran IPS yang menunjang pada pengembangan karir profesionalnya nanti. Kata kunci: metode simulasi, literasi informasi IPS, dan mahasiswa  Abstract. Social studies in elementary school subjects developed as an integrated or integrative social studies, not as educational disciplines. The challenges facing students today are many and varied social problems that must be faced in everyday life, so learning IPS aims to develop social skills. However, considering the development of elementary school students who are still in the level of concrete thinking it is advisable elementary social studies learning using examples of concrete social problems and that may involve experiences elementary students directly. But in reality based on the interviews of the teachers in the city of Serang there are still many difficulties in teaching social studies. This shows that the ability of teachers in primary

Pressurisation of IP-SOFC technology for second generation hybrid application

Energy Technology Data Exchange (ETDEWEB)

Jones, L.

2005-07-01

The Integrated Planar Solid Oxide Fuel Cell (IP-SOFC) technology developed by Rolls-Royce plc is a hybrid fuel cell technology considered highly suitable for the distributed power generation market. This report presents the results of a project to examine the technical viability of the IP-SOFC technology and some of the associated hybrid system component technologies under pressurised conditions and to investigate the validity of the predicted pressurisation phenomena. The work included: identification of critical material specifications, construction processes, control parameters, etc; the design and commissioning of two pressurised IP-SOFC test rigs at Rolls Royce in Derby; testing two multi-bundle strips at high temperature and atmospheric pressure; testing an active IP-SOFC bundle at high temperature and pressure; testing an experimental steam reforming unit at high temperature and pressure; testing a novel low pressure drop, off-gas combustor concept under atmospheric and pressurised conditions; design studies to identify key parameters affecting the successful integration and packaging of the fuel cell stack with certain associated hybrid components; and designing a hybrid system experimental verification rig. Significant progress was made in addressing the development challenges associated with the IP-SOFC of leakage, performance, durability, yield and geometry, the reaction rate of steam reforming and emissions from the off-gas combustor. Recommendations for future work are made.

Myricetin stimulates the absorption of the pro-carcinogen PhIP

NARCIS (Netherlands)

Schutte, M.E.; Sandt, J.J.M. van de; Alink, G.M.; Groten, J.P.; Rietjens, I.M.C.M.

2006-01-01

The effect of the flavonoid myricetin on the transport of the pro-carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) through differentiated Caco-2 monolayers, a model for the intestinal epithelium, is described. Myricetin causes an increase of the transport of PhIP from the apical to

Universal Space IP Transparent Proxy, Phase II

Data.gov (United States)

National Aeronautics and Space Administration — Communications applications are strategically moving toward Internet Protocol-based architectures and technologies. Despite IP's huge potential, (e.g. cost...

47 CFR 64.606 - VRS and IP Relay provider and TRS program certification.

Science.gov (United States)

2010-10-01

... 47 Telecommunication 3 2010-10-01 2010-10-01 false VRS and IP Relay provider and TRS program... Services and Related Customer Premises Equipment for Persons With Disabilities § 64.606 VRS and IP Relay... including notification in the Federal Register. (2) VRS and IP Relay provider. Any entity desiring to...

Novel characteristics of CtIP at damage-induced foci following the initiation of DNA end resection

International Nuclear Information System (INIS)

Fujisawa, Hiroshi; Fujimori, Akira; Okayasu, Ryuichi; Uesaka, Mitsuru; Yajima, Hirohiko

2015-01-01

Highlights: • CtIP becomes hyperphosphorylated and forms foci following cell irradiation. • CtIP accumulates in foci subsequent to the peak of hyperphosphorylation. • CtIP is maintained in a hypophosphorylated state at later times. • CtIP is continuously recruited to DNA double strand breaks downstream of resection. • CtIP presumably have a distinct role following the initiation of resection. - Abstract: Homologous recombination (HR) is a major repair pathway for DNA double strand breaks (DSBs), and end resection, which generates a 3′-single strand DNA tail at the DSB, is an early step in the process. Resection is initiated by the Mre11 nuclease together with CtIP. Here, we describe novel characteristics of CtIP at DSBs. At early times following exposure of human cells to ionizing radiation, CtIP localized to the DSB, became hyperphosphorylated and formed foci in an ATM-dependent manner. At later times, when the initiation of resection had occurred, CtIP foci persist but CtIP is maintained in a hypophosphorylated state, which is dependent on ATM and ATR. Exposure to cycloheximide revealed that CtIP turns over at DSB sites downstream of resection. Our findings provide strong evidence that CtIP is continuously recruited to DSBs downstream of both the initiation and extension step of resection, strongly suggesting that CtIP has functions in addition to promoting the initiation of resection during HR

Analisis Unjuk Kerja Aplikasi VoIP Call Android di Jaringan MANET [Performance Analysis of VoIP Call Application Android in MANET (Mobile Ad Hoc Network

Directory of Open Access Journals (Sweden)

Ryan Ari Setyawan

2015-06-01

Full Text Available Penelitian ini bertujuan menganalisis kinerja aplikasi  VoIP call android di jaringan MANET (mobile ad hoc network.  Hasil pengujian menunjukan bahwa aplikasi VoIP call android dapat digunakan di jaringan MANET. Delay yang dihasilkan paling besar di pengujian indoor dengan jarak 11-15 meter yakni sebesar 0,014624811 seconds. Packet loss yang dihasilkan pada range 1%-2% sedangkan standar packet loss yang ditetapkan oleh CISCO untuk layanan aplikasi VoIP adalah < 5%. Jitter yang dihasilkan yakni antara 0,01-0,06 seconds sedangkan standar yang ditetapkan oleh CISCO adalah ≤ 30 ms atau 0,03 seconds. Throughput yang dihasilkan pada proses pengujian yakni antar 161 kbps-481 kbps. *****This study aims to analyze the performance of VOIP call android application in the MANET (mobile ad hoc network. The results showed that VoIP applications could be implemented in MANET network. The highest  delay is produced in indoor testing  with distance of 11-15 meters,  which is equal to 0.014624811 seconds. Packet loss is generated in the range of 1% -2%, while packet loss standards set by Cisco for VoIP application services are <5%. The jitter is between 0.01 to 0.06 seconds, while the standard set by CISCO is ≤ 30 ms or 0.03 seconds. Throughput generated in the testing process is between 161 kbps-481 kbps.

Architecture and Design of IP Broadcasting System Using Passive Optical Network

Science.gov (United States)

Ikeda, Hiroki; Sugawa, Jun; Ashi, Yoshihiro; Sakamoto, Kenichi

We propose an IP broadcasting system architecture using passive optical networks (PON) utilizing the optical broadcast links of a PON with a downstream bandwidth allocation algorithm to provide a multi-channel IP broadcasting service to home subscribers on single broadband IP network infrastructures. We introduce the design and adaptation of the optical broadcast links to effectively broadcast video contents to home subscribers. We present a performance analysis that includes the downstream bandwidth utilization efficiency of the broadcast link and the bandwidth control of the IP broadcasting and Internet data. Our analysis and simulation results show that the proposed system can provide 100 HDTV channels to every user over fiber lines. We also propose an IPTV channel selection mechanism in an ONT by selecting a broadcast stream. We developed and evaluated a prototype that can achieve a 15-msec IPTV channel selection speed.

VoIP for Telerehabilitation: A Pilot Usability Study for HIPAA Compliance

Directory of Open Access Journals (Sweden)

Valerie R. Watzlaf

2012-06-01

Full Text Available Consumer-based, free Voice and video over the Internet Protocol (VoIP software systems such as Skype and others are used by health care providers to deliver telerehabilitation and other health-related services to clients. Privacy and security applications as well as HIPAA compliance within these protocols have been questioned by practitioners, health information managers, and other healthcare entities. This pilot usability study examined whether four respondents who used the top three, free consumer-based, VoIP software systems perceived these VoIP technologies to be private, secure, and HIPAA compliant;  most did not.  While the pilot study limitations include the number of respondents and systems assessed, the protocol can be applied to future research and replicated for instructional purposes.  Recommendations are provided for VoIP companies, providers, and users. 

CMT: a constrained multi-level thresholding approach for ChIP-Seq data analysis.

Directory of Open Access Journals (Sweden)

Iman Rezaeian

Full Text Available Genome-wide profiling of DNA-binding proteins using ChIP-Seq has emerged as an alternative to ChIP-chip methods. ChIP-Seq technology offers many advantages over ChIP-chip arrays, including but not limited to less noise, higher resolution, and more coverage. Several algorithms have been developed to take advantage of these abilities and find enriched regions by analyzing ChIP-Seq data. However, the complexity of analyzing various patterns of ChIP-Seq signals still needs the development of new algorithms. Most current algorithms use various heuristics to detect regions accurately. However, despite how many formulations are available, it is still difficult to accurately determine individual peaks corresponding to each binding event. We developed Constrained Multi-level Thresholding (CMT, an algorithm used to detect enriched regions on ChIP-Seq data. CMT employs a constraint-based module that can target regions within a specific range. We show that CMT has higher accuracy in detecting enriched regions (peaks by objectively assessing its performance relative to other previously proposed peak finders. This is shown by testing three algorithms on the well-known FoxA1 Data set, four transcription factors (with a total of six antibodies for Drosophila melanogaster and the H3K4ac antibody dataset.

Automatic Classification of Attacks on IP Telephony

Directory of Open Access Journals (Sweden)

Jakub Safarik

2013-01-01

Full Text Available This article proposes an algorithm for automatic analysis of attack data in IP telephony network with a neural network. Data for the analysis is gathered from variable monitoring application running in the network. These monitoring systems are a typical part of nowadays network. Information from them is usually used after attack. It is possible to use an automatic classification of IP telephony attacks for nearly real-time classification and counter attack or mitigation of potential attacks. The classification use proposed neural network, and the article covers design of a neural network and its practical implementation. It contains also methods for neural network learning and data gathering functions from honeypot application.

PERSPECTIVA DE NIÑOS Y NIÑAS DE TRANSICIÓN SOBRE NATURALEZA

Directory of Open Access Journals (Sweden)

Natalia Silva Garnica

2015-12-01

Full Text Available Se exploró la perspectiva de niños y niñas de transición sobre naturaleza.   Más específicamente se indagó cómo definen la naturaleza y el medio ambiente y qué sentimientos les genera. Participaron 49 niños y niñas entre los cinco y siete años de edad de dos instituciones de educación formal en el contexto urbano y se usaron diversas  herramientas  que  atendieron  la  expresión  oral,  escrita  y  gráfica.    Los resultados  muestran  que  los  niños  y  las  niñas  de  transición  tienden  a  definir  la naturaleza como elementos aislados, en su mayoría bióticos, que es confuso para ellos si los seres humanos hacemos parte de la naturaleza, que para ellos la naturaleza está a la vez cerca pero lejos y que medio ambiente es un concepto difícil de definir a esta edad. Manifestaron  sentimientos  positivos  frente  a  la  naturaleza  (emoción,  curiosidad, alegría, evidenciando biofilia en la primera infancia en el contexto citadino.   Las herramientas que capturan la voz de los niños resultaron siendo muy informativas pues muestran una perspectiva más dinámica y compleja.   Los resultados demuestran que niños y niñas de transición tienen una perspectiva clara sobre naturaleza y señalan algunos aspectos por fortalecer, en particular abordar más explícitamente la diversidad biológica y ambiental y reconocer que los humanos somos parte integral de ella y lo que esto implica

Automated Integration of Dedicated Hardwired IP Cores in Heterogeneous MPSoCs Designed with ESPAM

Directory of Open Access Journals (Sweden)

Ed Deprettere

2008-06-01

Full Text Available This paper presents a methodology and techniques for automated integration of dedicated hardwired (HW IP cores into heterogeneous multiprocessor systems. We propose an IP core integration approach based on an HW module generation that consists of a wrapper around a predefined IP core. This approach has been implemented in a tool called ESPAM for automated multiprocessor system design, programming, and implementation. In order to keep high performance of the integrated IP cores, the structure of the IP core wrapper is devised in a way that adequately represents and efficiently implements the main characteristics of the formal model of computation, namely, Kahn process networks, we use as an underlying programming model in ESPAM. We present details about the structure of the HW module, the supported types of IP cores, and the minimum interfaces these IP cores have to provide in order to allow automated integration in heterogeneous multiprocessor systems generated by ESPAM. The ESPAM design flow, the multiprocessor platforms we consider, and the underlying programming (KPN model are introduced as well. Furthermore, we present the efficiency of our approach by applying our methodology and ESPAM tool to automatically generate, implement, and program heterogeneous multiprocessor systems that integrate dedicated IP cores and execute real-life applications.

Cibermedios: Opinión de los lectores

Directory of Open Access Journals (Sweden)

Natalia Raimondo

2009-03-01

Full Text Available Se pretende sumar una voz más a la reflexión sobre aquellas mutaciones que conciernen a las alteraciones de la relación que los periódicos digitales establecen con sus lectores. La interactividad es lo más importante. Comentar, opinar y calificar un contenido es más significativo que consumir un texto.

Spojení s dynamickou IP adresou

Czech Academy of Sciences Publication Activity Database

Papík, Martin; Hodboď, J.

2013-01-01

Roč. 47, č. 2 (2013), s. 60-61 ISSN 1211-0906 R&D Projects: GA ČR GA13-02149S Institutional support: RVO:67985556 Keywords : dynamical IP adress * dynamic DNS * web services Subject RIV: JC - Computer Hardware ; Software

IP-telefon säästab oluliselt sidekulusid / Kristjan Otsmann

Index Scriptorium Estoniae

Otsmann, Kristjan, 1971-

2005-01-01

Telekomifirma Norby Telecomi poolt pakutavast IP-telefonist ehk helistamisest läbi Interneti, millega saab vähendada sidekulusid mitmeid kordi. Erinevatest internetipõhise kõnesidelahenduse lisateenustest. Vt. samas: Saaremaa Spa Hotellid säästab tuhandeid kroone kuus [intervjuu Saaremaa Spa Hotellide IT-juhiga Andri Võrguga]; Kuus olulist tööd enne IP-lahenduse tellimist

Software for rapid time dependent ChIP-sequencing analysis (TDCA).

Science.gov (United States)

Myschyshyn, Mike; Farren-Dai, Marco; Chuang, Tien-Jui; Vocadlo, David

2017-11-25

Chromatin immunoprecipitation followed by DNA sequencing (ChIP-seq) and associated methods are widely used to define the genome wide distribution of chromatin associated proteins, post-translational epigenetic marks, and modifications found on DNA bases. An area of emerging interest is to study time dependent changes in the distribution of such proteins and marks by using serial ChIP-seq experiments performed in a time resolved manner. Despite such time resolved studies becoming increasingly common, software to facilitate analysis of such data in a robust automated manner is limited. We have designed software called Time-Dependent ChIP-Sequencing Analyser (TDCA), which is the first program to automate analysis of time-dependent ChIP-seq data by fitting to sigmoidal curves. We provide users with guidance for experimental design of TDCA for modeling of time course (TC) ChIP-seq data using two simulated data sets. Furthermore, we demonstrate that this fitting strategy is widely applicable by showing that automated analysis of three previously published TC data sets accurately recapitulates key findings reported in these studies. Using each of these data sets, we highlight how biologically relevant findings can be readily obtained by exploiting TDCA to yield intuitive parameters that describe behavior at either a single locus or sets of loci. TDCA enables customizable analysis of user input aligned DNA sequencing data, coupled with graphical outputs in the form of publication-ready figures that describe behavior at either individual loci or sets of loci sharing common traits defined by the user. TDCA accepts sequencing data as standard binary alignment map (BAM) files and loci of interest in browser extensible data (BED) file format. TDCA accurately models the number of sequencing reads, or coverage, at loci from TC ChIP-seq studies or conceptually related TC sequencing experiments. TC experiments are reduced to intuitive parametric values that facilitate biologically

In-Pile Section(IPS) Inner Assembly Manufacturing Report

International Nuclear Information System (INIS)

Lee, Jong Min; Shim, Bong Sik; Lee, Chung Yong

2009-12-01

The objective of this report is to present the manufacturing, assembling and testing process of IPS Inner Assembly used in Fuel Test Loop(FTL) pre-operation test. The majority of the manufactured components are test fuels, inner assembly structures and subsidiary tools that is needed during the assembly process. In addition, Mock-up test for the welding and brazing is included at this stage. Lower structure, such as test fuels, fuel carrier legs are assembled and following structures, such as fuel carrier stem in the middle structure, top flange in the top structure are assembled together each other. To Verify the Reactor Coolant Pressure Boundary(RCPB) function in IPS Inner Assembly helium leak test and hydraulic test is performed with its acceptance criteria. According to the ASME III code Authorized Nuclear Inspector(ANI) is required during the hydraulic test. As-built measurement and insulation resistance test are performed to the structures and instrumentations after the test process. All requirements are satisfied and the IPS Inner Assembly was loaded in HANARO IR-1 hole in September 25, 2009

Introduction to IP address management

CERN Document Server

Rooney, Tim

2010-01-01

"The book begins with a basic overview of IP networking, followed by chapters describing each of the three core IPAM technologies: IPv4 and IPv6 addressing, DHCP, and DNS. The next three chapters describe IPAM management techniques and practice, followed by chapters on IPv4-IPv6 co-existence, security and the IPAM business case"--

Increasing supported VoIP flows in WMNs through link-based aggregation

CSIR Research Space (South Africa)

Olwal, T

2008-10-01

Full Text Available As Voice over IP (VoIP) becomes a reality, service providers will be able to offer the service to remote and over populated areas that currently are not or are only partially reached by available Public Switched Telephone Network (PSTN...

Performance Analysis of the Mobile IP Protocol (RFC 3344 and Related RFCS)

Science.gov (United States)

2006-12-01

field of 9 identifies the ICMP message as an adverstisement . Code Mobile IP home agents and foreign agents use the value of 16 to prevent any nodes...ANALYSIS OF THE MOBILE IP PROTOCOL (RFC 3344 AND RELATED RFCS) by Chin Chin Ng December 2006 Thesis Co-Advisors: George W. Dinolt J. D...December 2006 3. REPORT TYPE AND DATES COVERED Master’s Thesis 4. TITLE AND SUBTITLE Performance Analysis of the Mobile IP Protocol (RFC 3344 and

[Two years clinical observation of a kind of castable ceramic--IPS Empress].

Science.gov (United States)

Liu, Y; Li, Y; Nie, Y

1999-03-01

We used this material in clinic since 1995. Discussion on the prosthetic effects of the above-mentioned material to spreat it clinically. Through half to two years clinical observations to evaluate the effect of IPS Empress crowns in anterior teeth and inlays in posteriors. and Prosthesis made of this kind of material IPS Empress is one kind of excellent all-ceramic prosthetic material. IPS Empress also could be used in post crowns and the clinical effect was satisfactory.

POESÍA CORPORAL/DANZA VERBAL: UNA LECTURA COMPARADA DE HNUY ILLA

Directory of Open Access Journals (Sweden)

Iratxe Retolaza

2014-10-01

Full Text Available El espectáculo Hnuy illa (2008, coproducción de Kukai-Tanttaka, se articuló en la intersección entre danza y poesía. Este espectáculo de danza está basado en el imaginario poético del escritor vasco Joseba Sarrionandia. Consideramos que esta transferencia cultural del texto poético al texto coreográfico, nos ofrece un marco interpretativo muy apropiado para poder reflexionar sobre las representaciones del cuerpo y de la voz. ¿Cómo se presenta y representa el cuerpo en el texto poético? ¿Cómo se presenta y representa la voz en el texto coreográfico? ¿Cómo se transfiere esa presencia y representación corporal a la danza?

GMI-IPS: Python Processing Software for Aircraft Campaigns

Science.gov (United States)

Damon, M. R.; Strode, S. A.; Steenrod, S. D.; Prather, M. J.

2018-01-01

NASA's Atmospheric Tomography Mission (ATom) seeks to understand the impact of anthropogenic air pollution on gases in the Earth's atmosphere. Four flight campaigns are being deployed on a seasonal basis to establish a continuous global-scale data set intended to improve the representation of chemically reactive gases in global atmospheric chemistry models. The Global Modeling Initiative (GMI), is creating chemical transport simulations on a global scale for each of the ATom flight campaigns. To meet the computational demands required to translate the GMI simulation data to grids associated with the flights from the ATom campaigns, the GMI ICARTT Processing Software (GMI-IPS) has been developed and is providing key functionality for data processing and analysis in this ongoing effort. The GMI-IPS is written in Python and provides computational kernels for data interpolation and visualization tasks on GMI simulation data. A key feature of the GMI-IPS, is its ability to read ICARTT files, a text-based file format for airborne instrument data, and extract the required flight information that defines regional and temporal grid parameters associated with an ATom flight. Perhaps most importantly, the GMI-IPS creates ICARTT files containing GMI simulated data, which are used in collaboration with ATom instrument teams and other modeling groups. The initial main task of the GMI-IPS is to interpolate GMI model data to the finer temporal resolution (1-10 seconds) of a given flight. The model data includes basic fields such as temperature and pressure, but the main focus of this effort is to provide species concentrations of chemical gases for ATom flights. The software, which uses parallel computation techniques for data intensive tasks, linearly interpolates each of the model fields to the time resolution of the flight. The temporally interpolated data is then saved to disk, and is used to create additional derived quantities. In order to translate the GMI model data to the

Firewall for Dynamic IP Address in Mobile IPv6

Science.gov (United States)

Qiu, Ying; Bao, Feng; Zhou, Jianying

Mobile communication is becoming the mainstream with the rapid growth of mobile devices penetrating our daily life. More and more mobile devices such as mobile phones, personal digital assistants, notebooks etc, are capable of Internet access. Mobile devices frequently change their communication IP addresses in mobile IPv6 network following its current attached domain. This raises a big challenge for building firewall for mobile devices. The conventional firewalls are primarily based on IPv4 networks where the security criteria are specified only to the fixed IP addresses or subnets, which apparently do not apply to mobile IPv6. In this paper we propose three solutions for mobile IPv6 firewall. Our approaches make the firewall adaptive to dynamic IP addresses in mobile IPv6 network. They have different expense and weight corresponding to different degree of universality. The paper focuses the study more from practical aspect.

Application Filters for TCP/IP Industrial Automation Protocols

Science.gov (United States)

Batista, Aguinaldo B.; Kobayashi, Tiago H.; Medeiros, João Paulo S.; Brito, Agostinho M.; Motta Pires, Paulo S.

The use of firewalls is a common approach usually meant to secure Automation Technology (AT) from Information Technology (TI) networks. This work proposes a filtering system for TCP/IP-based automation networks in which only certain kind of industrial traffic is permitted. All network traffic which does not conform with a proper industrial protocol pattern or with specific rules for its actions is supposed to be abnormal and must be blocked. As a case study, we developed a seventh layer firewall application with the ability of blocking spurious traffic, using an IP packet queueing engine and a regular expression library.

Encrypted IP video communication system

Science.gov (United States)

Bogdan, Apetrechioaie; Luminiţa, Mateescu

2010-11-01

Digital video transmission is a permanent subject of development, research and improvement. This field of research has an exponentially growing market in civil, surveillance, security and military aplications. A lot of solutions: FPGA, ASIC, DSP have been used for this purpose. The paper presents the implementation of an encrypted, IP based, video communication system having a competitive performance/cost ratio .

Determination of alpha particle detection efficiency of an imaging plate (IP) detector

International Nuclear Information System (INIS)

Rahman, N.M; Iida, Takao; Yamazawa, Hiromi; Moriizumi, Jun

2006-01-01

In order to determine the detection efficiency of the imaging plate (IP) detector, the true radioactivity of the alpha particles, which sampled in the collection media, should be known. The true radioactivity could be accurately predicted with the help of the reference alpha spectrometer measurement. The detection efficiency calculated for the IP was estimated with the theoretical curve and the experimental data. It is assumed that the air sample contained the decay products of both 222 Rn and 220 Rn series, the most significant sources of alpha particles. The present study estimated the detection efficiency of the IP as 39.3% with an uncertainty of 2.9 that is well enough to confirm the future use of the IP as a radiation detector. Experimental materials and methods are described. (S.Y.)

ChIP-exo interrogation of Crp, DNA, and RNAP holoenzyme interactions

DEFF Research Database (Denmark)

Latif, Haythem; Federowicz, Stephen; Ebrahim, Ali

2018-01-01

Numerous in vitro studies have yielded a refined picture of the structural and molecular associations between Cyclic-AMP receptor protein (Crp), the DNA motif, and RNA polymerase (RNAP) holoenzyme. In this study, high-resolution ChIP-exonuclease (ChIP-exo) was applied to study Crp binding in vivo...

Inhibition by salmeterol and cilomilast of fluticasone-enhanced IP-10 release in airway epithelial cells.

Science.gov (United States)

Reddy, P J; Aksoy, Mark O; Yang, Yi; Li, Xiu Xia; Ji, Rong; Kelsen, Steven G

2008-02-01

The CXC chemokines, IP-10/CXCL10 and IL-8/CXCL8, play a role in obstructive lung disease by attracting Th1/Tc1 lymphocytes and neutrophils, respectively. Inhaled corticosteroids (ICS) and long acting beta 2-agonists (LABA) are widely used. However, their effect(s) on the release of IP-10 and IL-8 by airway epithelial cells are poorly understood. This study examined the effects of fluticasone, salmeterol, and agents which raise intracellular cAMP (cilomilast and db-cAMP) on the expression of IP-10 and IL-8 protein and mRNA. Studies were performed in cultured human airway epithelial cells during cytokine-stimulated IP-10 and IL-8 release. Cytokine treatment (TNF-alpha, IL-1beta and IFN-gamma) increased IP-10 and IL-8 protein and mRNA levels. Fluticasone (0.1 nM to 1 microM) increased IP-10 but reduced IL-8 protein release without changing IP-10 mRNA levels assessed by real time RT-PCR. The combination of salmeterol (1 micro M) and cilomilast (1-10 mu M) reduced IP-10 but had no effect on IL-8 protein. Salmeterol alone (1 micro M) and db-cAMP alone (1 mM) antagonised the effects of fluticasone on IP-10 but not IL-8 protein. In human airway epithelial cells, inhibition by salmeterol of fluticasone-enhanced IP-10 release may be an important therapeutic effect of the LABA/ICS combination not present when the two drugs are used separately.

A Review on Hot-IP Finding Methods and Its Application in Early DDoS Target Detection

Directory of Open Access Journals (Sweden)

Xuan Dau Hoang

2016-10-01

Full Text Available On the high-speed connections of the Internet or computer networks, the IP (Internet Protocol packet traffic passing through the network is extremely high, and that makes it difficult for network monitoring and attack detection applications. This paper reviews methods to find the high-occurrence-frequency elements in the data stream and applies the most efficient methods to find Hot-IPs that are high-frequency IP addresses of IP packets passing through the network. Fast finding of Hot-IPs in the IP packet stream can be effectively used in early detection of DDoS (Distributed Denial of Service attack targets and spreading sources of network worms. Research results show that the Count-Min method gives the best overall performance for Hot-IP detection thanks to its low computational complexity, low space requirement and fast processing speed. We also propose an early detection model of DDoS attack targets based on Hot-IP finding, which can be deployed on the target network routers.

Inference of hierarchical regulatory network of estrogen-dependent breast cancer through ChIP-based data

Directory of Open Access Journals (Sweden)

Parvin Jeffrey

2010-12-01

Full Text Available Abstract Background Global profiling of in vivo protein-DNA interactions using ChIP-based technologies has evolved rapidly in recent years. Although many genome-wide studies have identified thousands of ERα binding sites and have revealed the associated transcription factor (TF partners, such as AP1, FOXA1 and CEBP, little is known about ERα associated hierarchical transcriptional regulatory networks. Results In this study, we applied computational approaches to analyze three public available ChIP-based datasets: ChIP-seq, ChIP-PET and ChIP-chip, and to investigate the hierarchical regulatory network for ERα and ERα partner TFs regulation in estrogen-dependent breast cancer MCF7 cells. 16 common TFs and two common new TF partners (RORA and PITX2 were found among ChIP-seq, ChIP-chip and ChIP-PET datasets. The regulatory networks were constructed by scanning the ChIP-peak region with TF specific position weight matrix (PWM. A permutation test was performed to test the reliability of each connection of the network. We then used DREM software to perform gene ontology function analysis on the common genes. We found that FOS, PITX2, RORA and FOXA1 were involved in the up-regulated genes. We also conducted the ERα and Pol-II ChIP-seq experiments in tamoxifen resistance MCF7 cells (denoted as MCF7-T in this study and compared the difference between MCF7 and MCF7-T cells. The result showed very little overlap between these two cells in terms of targeted genes (21.2% of common genes and targeted TFs (25% of common TFs. The significant dissimilarity may indicate totally different transcriptional regulatory mechanisms between these two cancer cells. Conclusions Our study uncovers new estrogen-mediated regulatory networks by mining three ChIP-based data in MCF7 cells and ChIP-seq data in MCF7-T cells. We compared the different ChIP-based technologies as well as different breast cancer cells. Our computational analytical approach may guide biologists to

Saúde vocal do professor: intervenção fonoaudiológica na atenção primária à saúde

Directory of Open Access Journals (Sweden)

Ivana Arrais de Lavor Navarro Xavier

2013-08-01

Full Text Available OBJETIVO: apresentar uma ação de promoção a saúde vocal dos professores de três escolas municipais situadas no Distrito Sanitário III, em Recife-PE, no âmbito da Atenção Primária à Saúde - APS. MÉTODO: foi aplicado um questionário sobre o histórico vocal dos professores e realizadas seis oficinas de voz, com o intuito de sensibilizar os docentes sobre a importância dos cuidados com a voz e incentivar a prática dos exercícios vocais preventivamente como ação cotidiana dentro do processo de trabalho. Por fim, foi aplicado um questionário para avaliar a percepção dos docentes em relação às oficinas. RESULTADOS: as educadoras encontravam-se na faixa etária de 17-55 anos, tinham 10,4 anos em média de exercício profissional e 96,3% relatou a percepção de problemas com a voz ou fala, sendo que quanto maior a frequência de aparecimento do problema, maior era o tempo de exercício profissional, a jornada de trabalho e a idade. Os depoimentos foram positivos em relação às oficinas, sendo que 80% das docentes referiu melhora no desempenho profissional e 93,3% afirmou que continuará realizando os exercícios, mas apontaram a falta de tempo como principal dificuldade para realização dos exercícios rotineiramente. CONCLUSÃO: estes resultados identificam a importância da introdução de ações voltadas à saúde do professor com o intuito de amenizar os efeitos do trabalho sobre sua saúde, e a inserção do fonoaudiólogo na APS a fim de facilitar estas ações na prática cotidiana. A utilização do espaço escolar permite configurá-lo como espaço social para tomada de consciência, reflexão, discussão sobre as condições de trabalho e como um ambiente saudável.

Multiplexed ChIP-Seq Using Direct Nucleosome Barcoding: A Tool for High-Throughput Chromatin Analysis.

Science.gov (United States)

Chabbert, Christophe D; Adjalley, Sophie H; Steinmetz, Lars M; Pelechano, Vicent

2018-01-01

Chromatin immunoprecipitation followed by sequencing (ChIP-Seq) or microarray hybridization (ChIP-on-chip) are standard methods for the study of transcription factor binding sites and histone chemical modifications. However, these approaches only allow profiling of a single factor or protein modification at a time.In this chapter, we present Bar-ChIP, a higher throughput version of ChIP-Seq that relies on the direct ligation of molecular barcodes to chromatin fragments. Bar-ChIP enables the concurrent profiling of multiple DNA-protein interactions and is therefore amenable to experimental scale-up, without the need for any robotic instrumentation.

Intelligent Advanced Communications IP Telephony Feasibility for the U.S. Navy (DVD)

National Research Council Canada - National Science Library

Binns, Todd D; Naas, Bill

2007-01-01

...: 2 DVD-ROMs; 4 3/4 in.; 2.68 GB. ABSTRACT: The purpose of this research paper is to research technologies and solutions supporting the communications infrastructure necessary to implement an integrated VoIP (IP telephony...

Vítimas e culpadas: representações sociais sobre mulheres que vivem com HIV

Directory of Open Access Journals (Sweden)

Bruna Alessandra Costa e Silva Panarra

2017-09-01

Full Text Available Introdução: Objetivou-se apreender as representações sociais de profissionais de saúde sobre mulheres que vivem com HIV. Materiais e Métodos: Pesquisa qualitativa e descritiva, com base na Teoria das Representações Sociais. Realizou-se entrevistas com 37 profissionais de serviços de referência em HIV de Belém-Pará, no período de setembro de 2012 a junho 2013. Resultados: O corpus foi submetido à análise pelo software Alceste gerando cinco classes, dentre estas: representações sociais dos profissionais de saúde sobre pessoas que vivem com HIV. Discussão: Os léxicos ilustrativos da classe apontaram a vitimização e a culpabilização da mulher com HIV. Há conteúdos positivos e negativos, dependendo do modo de contaminação. Conclusões: O HIV desperta sentimentos negativos: pena, revolta e culpa. As mulheres são categorizadas e julgadas pelos profissionais, podendo ser vítimas ou culpadas. Há necessidade de políticas de educação permanente aos profissionais de saúde sobre o HIV para que possam desconstruir tais conteúdos. Como citar este artigo: Panarra BACS, Teixeira E, Palmeira IP, Rodrigues ILA, Ferreira AMR. Vítimas e culpadas: representações sociais sobre mulheres que vivem com HIV. Rev Cuid. 2017; 8(3: 1887-98. http:/dx.doi.org/10.15649/cuidarte.v8i3.451

Post-translational inhibition of IP-10 secretion in IEC by probiotic bacteria: impact on chronic inflammation.

Directory of Open Access Journals (Sweden)

Gabriele Hoermannsperger

Full Text Available BACKGROUND: Clinical and experimental studies suggest that the probiotic mixture VSL#3 has protective activities in the context of inflammatory bowel disease (IBD. The aim of the study was to reveal bacterial strain-specific molecular mechanisms underlying the anti-inflammatory potential of VSL#3 in intestinal epithelial cells (IEC. METHODOLOGY/PRINCIPAL FINDINGS: VSL#3 inhibited TNF-induced secretion of the T-cell chemokine interferon-inducible protein (IP-10 in Mode-K cells. Lactobacillus casei (L. casei cell surface proteins were identified as active anti-inflammatory components of VSL#3. Interestingly, L. casei failed to block TNF-induced IP-10 promoter activity or IP-10 gene transcription at the mRNA expression level but completely inhibited IP-10 protein secretion as well as IP-10-mediated T-cell transmigration. Kinetic studies, pulse-chase experiments and the use of a pharmacological inhibitor for the export machinery (brefeldin A showed that L. casei did not impair initial IP-10 production but decreased intracellular IP-10 protein stability as a result of blocked IP-10 secretion. Although L. casei induced IP-10 ubiquitination, the inhibition of proteasomal or lysosomal degradation did not prevent the loss of intracellular IP-10. Most important for the mechanistic understanding, the inhibition of vesicular trafficking by 3-methyladenine (3-MA inhibited IP-10 but not IL-6 expression, mimicking the inhibitory effects of L. casei. These findings suggest that L. casei impairs vesicular pathways important for the secretion of IP-10, followed by subsequent degradation of the proinflammatory chemokine. Feeding studies in TNF(DeltaARE and IL-10(-/- mice revealed a compartimentalized protection of VSL#3 on the development of cecal but not on ileal or colonic inflammation. Consistent with reduced tissue pathology in IL-10(-/- mice, IP-10 protein expression was reduced in primary epithelial cells. CONCLUSIONS/SIGNIFICANCE: We demonstrate segment

Triazolophostins: a library of novel and potent agonists of IP3 receptors

OpenAIRE

Vibhute, Amol M; Konieczny, Vera; Taylor, Colin William; Sureshan, Kana M

2015-01-01

IP3 receptors are channels that mediate the release of Ca2+ from the intracellular stores of cells stimulated by hormones or neurotransmitters. Adenophostin A (AdA) is the most potent agonist of IP3 receptors, with the β-anomeric adenine contributing to the increased potency. The potency of AdA and its stability towards the enzymes that degrade IP3 have aroused interest in AdA analogs for biological studies. The complex structure of AdA poses problems that have necessitated optimization of sy...

Developing VoIP Honeypots: a Preliminary Investigation into Malfeasant Activity

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Craig Valli

2010-06-01

Full Text Available 30 years ago PABX systems were compromised by hackers wanting to make long distance calls at some other entities expense. This activity faded as telephony became cheaper and PABX systems had countermeasures installed to overcome attacks. Now the world has moved onto the provision of telephony via broadband enabled Voice over Internet Protocol (VoIP with this service now being provided as a replacement for conventional fixed wire telephony by major telecommunication providers worldwide. Due to increasing bandwidth it is possible for systems to support multiple voice connections simultaneously. The networked nature of the Internet allows for attackers of these VoIP systems to enumerate and potentially attack and compromise a wide range of vulnerable systems. This paper is an outline of preliminary research into malfeasant VoIP activity on the Internet.

Which IP Strategies Do Young Highly Innovative Firms Choose

DEFF Research Database (Denmark)

Veugelers, Reinhilde; Schneider, Cédric

2018-01-01

This paper describes and analyzes the strategies of young highly innovative companies to appropriate the returns from their innovations. Upon controlling for other firm and industry characteristics, we show that firms combining a young age and small scale with a high R&D intensive profile are mor...... likely to use intellectual property (IP), specifically combining formal and informal appropriation mechanisms. They are especially more likely to choose secrecy in combination with formal IP. This holds primarily when they introduce more radical innovations new to the market....

A simple method to quantitate IP-10 in dried blood and plasma spots.

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Martine G Aabye

Full Text Available BACKGROUND: Antigen specific release of IP-10 is an established marker for infection with M.tuberculosis. Compared to IFN-γ, IP-10 is released in 100-fold higher concentrations enabling the development of novel assays for detection. Dried blood spots are a convenient sample for high throughput newborn screening. AIM: To develop a robust and sensitive ELISA-based assay for IP-10 detection in plasma, dried blood spots (DBS and dried plasma spots (DPS; to validate the ELISA in clinically relevant samples; and to assess the performance of the assay for detection of Cytomegalovirus (CMV and M.tuberculosis specific immune responses. METHOD: We raised mice and rat monoclonal antibodies against human IP-10 and developed an ELISA. The assay was validated and applied to the detection of CMV and M.tuberculosis specific responses in 18 patients with immune reactivity towards M.tuberculosis and 32 healthy controls of which 22 had immune reactivity towards CMV and none towards M.tuberculosis. We compared the performance of this new assay to IFN-γ. RESULTS: The ELISA was reliable for IP-10 detection in both plasma and filter paper samples. The linear range of the ELISA was 2.5-600 pg/ml. IFN-γ was not readily detectable in DPS samples. IP-10 was stabile in filter paper samples for at least 4 weeks at 37 °C. The correlation between IP-10 detected in plasma, DPS and DBS samples was excellent (r(2>0.97. CONCLUSIONS: This newly developed assay is reliable for IP-10 quantification in plasma, DBS and DPS samples from antigen stimulated and non-stimulated whole blood. The filter paper assays enable easy sample acquisition and transport at ambient temperature e.g. via the postal system. The system can potentially simplify diagnostic assays for M.tuberculosis and CMV infection.

Redox routes to substitution of aluminum(III): synthesis and characterization of (IP-)2AlX (IP = α-iminopyridine, X = Cl, Me, SMe, S2CNMe2, C≡CPh, N3, SPh, NHPh).

Science.gov (United States)

Myers, Thomas W; Holmes, Alexandra L; Berben, Louise A

2012-08-20

Redox active ligands are shown to facilitate a variety of group transfer reactions at redox inert aluminum(III). Disulfides can be used as a two-electron group transfer reagent, and we show that (IP(-))(2)AlSR can be formed by reaction of [(THF)(6)Na][(IP(2-))(2)Al] (1c) with disulfides RSSR (where X = C(S)NMe(2), 4; SMe, 5). In a more general redox route to substitution of aluminum bis(iminopyridine) complexes, we report zinc(II) salts as a group transfer reagent. Reaction of [((R)IP(2-))(2)Al](-) (R = H, 1c; Me, 1d) with ZnX(2) affords ((R)IP(-))(2)AlX (where IP = iminopyridine, R = H, and X = Cl, 2; CCPh, 6; N(3), 7; SPh, 8; or R = Me and X = NHPh, 9). Single crystal X-ray diffraction analysis of the complexes reveal that each of the five coordinate complexes reported here has a trigonal bipyramidal geometry with τ = 0.668 - 0.858. We observed a correlation between the greatest deviations from ideal trigonal bipyramidal symmetry (lowest τ values), the bond lengths consistent with smallest degree of ligand reduction, and the least polarizable X ligand in (IP(-))(2)AlX. Complex 4 is six-coordinate and is best described as distorted octahedral. Variable temperature magnetic susceptibility measurements indicate that each of the complexes 3-9 has a biradical electronic structure similar to previously reported 2. Magnetic exchange coupling constants in the range J = -94 to -212 cm(-1) were fit to the data for 2-9 to describe the energy of antiferromagnetic interaction between ligand radicals assuming a spin Hamiltonian of the form Ĥ = -2JŜ(L(1))·Ŝ(L(2)). The strongest coupling occurs when the angle between the ligand planes is smallest, presumably to afford good overlap with the Al-X σ* orbital. Electrochemical properties of the complexes were probed using cyclic voltammetry and each of 3-9 displayed a reversible two-electron reduction and two quasi-reversible one-electron oxidation processes. The energy of the ligand based redox processes for 2-9 differ by

Considerações teóricas sobre a relação entre respiração oral e disfonia Theoretical considerations on the relationship between mouth breathing and dysphonia

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Juliana Gomes Tavares

2008-01-01

Full Text Available Sabe-se que a respiração oral pode ocasionar diversas alterações ósseas, posturais, musculares e funcionais, como também, alterações na qualidade e/ou comportamento vocal. Estas alterações podem comprometer a comunicação oral, na qual a voz não consegue desempenhar seu papel básico de transmissão da mensagem verbal e emocional do indivíduo. O indivíduo com respiração oral pode apresentar ressonância nasalizada e a voz pode apresentar alterações no traço de sonoridade, hiper ou hiponasal, ou rouca. A partir de pesquisa nas bases de dados LILACS, SciELO, livros, revistas especializadas sobre o tema, buscamos fazer uma revisão na literatura sobre a relação entre respiração oral e disfonia, analisando a influência das alterações causadas pela respiração oral na qualidade e/ou comportamento vocal. No entanto, foi possível observar que a respiração oral promove uma série de alterações estruturais significativas que refletem nas funções estomatognáticas, interferindo também na fonação. Contudo, poucos autores relatam a possível correlação entre esses dois parâmetros (respiração oral e disfonia.It is known that mouth breathing can lead to several bone, postural, muscular and functional alterations, and also changes on vocal quality and/or vocal behavior. These alterations can compromise oral communication, in which the voice cannot perform its basic role on the transmission of an individual's verbal and emotional message. Individuals with mouth breathing can present hiper or hiponasal resonance, changes on voicing features and hoarseness. From researches on LILACS and SciELO databases, books and specialized magazines about the subject, it was carried a literature review about the relationship between mouth breathing and dysphonia, analyzing the influence of alterations caused by mouth breathing on vocal quality and/or vocal behavior. It was possible observe that mouth breathing promotes several

Model-Based Learning Environment Based on The Concept IPS School-Based Management

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Hamid Darmadi

2017-03-01

Full Text Available The results showed: (1 learning model IPS-oriented environment can grow and not you love the cultural values of the area as a basis for the development of national culture, (2 community participation, and the role of government in implementing learning model of IPS-based environment provides a positive impact for the improvement of management school resources, (3 learning model IPS-based environment effectively creating a way of life together peacefully, increase the intensity of togetherness and mutual respect (4 learning model IPS-based environment can improve student learning outcomes, (5 there are differences in the expression of attitudes and results learning among students who are located in the area of conflict with students who are outside the area of conflict (6 analysis of the scale of attitudes among school students da SMA result rewards high school students to the values of unity and nation, respect for diversity and peaceful coexistence, It is recommended that the Department of Education authority as an institution of Trustees and the development of social and cultural values in the province can apply IPS learning model based environments.

IP-I0 BASED IMMUNOLOGICAL MONITORING

DEFF Research Database (Denmark)

2008-01-01

The present invention relates to an immunological method and, more particularly, a method for measuring cell-mediated immune reactivity (CMI) in mammals based on the production of IP-10.The invention further discloses an assay and a kit for measuring CMI to an antigen using whole blood or other...

ß-Phellandrene: Kairomone for Pine Engraver, Ips pini (Say) (Coleoptera: Scolytidae)

Science.gov (United States)

Daniel R. Miller; John H. Borden

1990-01-01

The responses of Ips pini (Scolytidae) to multiple-funnel traps baited with the pheromone, ipsdienol, and various monoterpenes were determined in stands of lodgepole pine in southern and central British Columbia. Ips pini was attracted to both ipsdienol and ß-phellandrene, demonstrating that ß-phellandrene is a kairomone for this...

Functional role of EF-hands 3 and 4 in membrane-binding of KChIP1

Indian Academy of Sciences (India)

Prakash

type KChIP1, truncated KChIP1 exhibited lower lipid-binding capability. Compared with wild-type KChIP1, increasing membrane permeability by the use of digitonin caused a marked .... with sonication, the supernatant (soluble protein fractions).

Cyclic ADP-ribose and IP3 mediate abscisic acid-induced isoflavone accumulation in soybean sprouts

International Nuclear Information System (INIS)

Jiao, Caifeng; Yang, Runqiang; Gu, Zhenxin

2016-01-01

In this study, the roles of ABA-cADPR-Ca 2+ and ABA-IP3-Ca 2+ signaling pathways in UV-B-induced isoflavone accumulation in soybean sprouts were investigated. Results showed that abscisic acid (ABA) up regulated cyclic ADP-ribose (cADPR) and inositol 1,4,5-trisphosphate (IP3) levels in soybean sprouts under UV-B radiation. Furthermore, cADPR and IP3, as second messengers of UV-B-triggered ABA, induced isoflavone accumulation by up-regulating proteins and genes expression and activity of isoflavone biosynthetic-enzymes (chalcone synthase, CHS; isoflavone synthase, IFS). After Ca 2+ was chelated by EGTA, isoflavone content decreased. Overall, ABA-induced cADPR and IP3 up regulated isoflavone accumulation which was mediated by Ca 2+ signaling via enhancing the expression of proteins and genes participating in isoflavone biosynthesis in soybean sprouts under UV-B radiation. - Highlights: • UV-B-induced cADPR and IP3 synthesis was mediated by ABA. • cADPR and IP3 were involved in UV-B-ABA-induced isoflavone accumulation. • cADPR and IP3-induced isoflavone accumulation may be mediated by Ca 2+ . • ABA, cADPR, IP3 and Ca 2+ could activate proteins expression of CHS and IFS.

A novel fusion protein of IP10-scFv retains antibody specificity and chemokine function

International Nuclear Information System (INIS)

Guo Junqing; Chen Liu; Ai Hongwu; Jing Jiannian; Zhou Jiyong; Zhang Chuyu; You Shangyou

2004-01-01

We combined the specificity of tumor-specific antibody with the chemokine function of interferon-γ inducible protein 10 (IP-10) to recruit immune effector cells in the vicinity of tumor cells. A novel fusion protein of IP10-scFv was constructed by fusing mouse IP-10 to V H region of single-chain Fv fragment (scFv) against acidic isoferritin (AIF), and expressed in NS0 murine myeloma cells. The IP10-scFv fusion protein was shown to maintain the specificity of the antiAIF scFv with similar affinity constant, and bind to the human hepatocarcinoma SMMC 7721 cells secreting AIF as well as the activated mouse T lymphocytes expressing CXCR3 receptor. Furthermore, the IP10-scFv protein either in solution or bound on the surface of SMMC 7721 cells induced significant chemotaxis of mouse T cells in vitro. The results indicate that the IP10-scFv fusion protein possesses both bioactivities of the tumor-specific antibody and IP-10 chemokine, suggesting its possibility to induce an enhanced immune response against the residual tumor cells in vivo

Riscos ocupacionais na legislação trabalhista brasileira: destaque para aqueles relativos à saúde e à voz do professor Occupational risks in the Brazilian labor legislation: highlight on those related to teacher's health and voice

Directory of Open Access Journals (Sweden)

Emilse Aparecida Merlin Servilha

2010-12-01

Full Text Available OBJETIVO: Analisar a legislação a respeito de riscos ocupacionais, com destaque para aqueles relacionados à saúde e à voz do professor. MÉTODOS: Trata-se de pesquisa bibliográfica, de caráter qualitativo, que considerou as políticas públicas sobre Saúde e Segurança no Trabalho. As Normas Regulamentadoras foram lidas e seus conteúdos analisados e organizados por categorias, com recorte para aqueles referentes ao ambiente escolar. RESULTADOS: As 33 normas focalizam os fatores de risco, níveis de tolerância e controle para saúde e segurança no trabalho. Os agentes ambientais nocivos são múltiplos e suas especificidades, como concentração e frequência, determinam o nível de tolerância à exposição. Na escola, os riscos ambientais como ruído, poeira, temperatura e iluminação inadequadas, dentre outros, estão presentes, porém em grau leve. O tratamento acústico, de iluminação e de ventilação é indicado para controle desses riscos. Os documentos mostram situações de agravos à saúde dos trabalhadores em graus de risco muito maiores do que aqueles da docência. Não há explicitação de fatores inerentes à organização do trabalho e os cuidados com a voz limitam-se à profissão de teleoperador, o que pode servir de referência para o professor. CONCLUSÃO: A legislação trabalhista é ampla ao abarcar a diversidade de condições de trabalho e garantir a saúde dos trabalhadores. A docência apresenta riscos ocupacionais à saúde mais leves do que outras profissões; contudo, os fatores organizacionais do trabalho, assim como os distúrbios de voz, muito frequentes na docência, carecem de maior atenção da legislação no Brasil.PURPOSE: To analyze the legislation regarding occupational risks, highlighting those related to teacher's health and voice. METHODS: A bibliographic search of qualitative nature regarding the public policies about Health and Security at Work was carried out. The Regulatory

Implementación y comparación de algoritmos basados en técnicas biométricas de voz para reconocimiento de locutor en colaboración con la empresa IECISA

OpenAIRE

Ugarte Echeverría, María Elísabe

2010-01-01

Este proyecto fin de carrera se enmarca en el área de procesado de señal, y tiene como objetivo obtener un sistema de reconocimiento de locutores. Esta técnica biométrica está fundamentada en las características de la voz de cada individuo. El modelado de las voces se realiza utilizando mezclas gaussianas y la caracterización está basada en escala Mel. Ingeniería de Telecomunicación Telekomunikazio Ingeniaritza

Cell-type specificity of ChIP-predicted transcription factor binding sites

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Håndstad Tony

2012-08-01

Full Text Available Abstract Background Context-dependent transcription factor (TF binding is one reason for differences in gene expression patterns between different cellular states. Chromatin immunoprecipitation followed by high-throughput sequencing (ChIP-seq identifies genome-wide TF binding sites for one particular context—the cells used in the experiment. But can such ChIP-seq data predict TF binding in other cellular contexts and is it possible to distinguish context-dependent from ubiquitous TF binding? Results We compared ChIP-seq data on TF binding for multiple TFs in two different cell types and found that on average only a third of ChIP-seq peak regions are common to both cell types. Expectedly, common peaks occur more frequently in certain genomic contexts, such as CpG-rich promoters, whereas chromatin differences characterize cell-type specific TF binding. We also find, however, that genotype differences between the cell types can explain differences in binding. Moreover, ChIP-seq signal intensity and peak clustering are the strongest predictors of common peaks. Compared with strong peaks located in regions containing peaks for multiple transcription factors, weak and isolated peaks are less common between the cell types and are less associated with data that indicate regulatory activity. Conclusions Together, the results suggest that experimental noise is prevalent among weak peaks, whereas strong and clustered peaks represent high-confidence binding events that often occur in other cellular contexts. Nevertheless, 30-40% of the strongest and most clustered peaks show context-dependent regulation. We show that by combining signal intensity with additional data—ranging from context independent information such as binding site conservation and position weight matrix scores to context dependent chromatin structure—we can predict whether a ChIP-seq peak is likely to be present in other cellular contexts.

Evaluation of VoIP QoS Performance in Wireless Mesh Networks

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Mohammad Tariq Meeran

2017-07-01

Full Text Available The main focus of this research article is the evaluation of selected voice over Internet protocol (VoIP solutions in wireless mesh network (WMN scenarios. While WMNs have self-healing, self-forming, and dynamic topology features, they still pose challenges for the implementation of multimedia applications such as voice in various scenarios. Therefore, various solutions to make WMN more suitable for VoIP application have been proposed in the scientific literature. In this work, we have extensively explored a set of applicable scenarios by conducting experiments by means of a network simulator. The following scenarios were selected as the most representatives for performance evaluation: first responders, flooded village, remote village, and platoon deployment. Each selected scenario has been studied under six sub-scenarios corresponding to various combinations of the IEEE 802.11g, 802.11n, 802.11s, and 802.11e standards; the G.711 and G.729 codecs; and the ad hoc on demand distance vector (AODV and hybrid wireless mesh protocol (HWMP routing protocols. The results in terms of quality of service (measured with the mean opinion score rating scale, supported by the analysis of delay, jitter and packet loss, show that 802.11g integration with both VoIP codecs and AODV routing protocol results in better VoIP performance as compared to most other scenarios. In case of 802.11g integration with 802.11s, VoIP performance decreases as compared to the other sub-scenarios without 802.11s. The results also show that 802.11n integration with 802.11e decreases VoIP performance in larger deployments. We conclude the paper with some recommendations in terms of combinations of those standards and protocols with a view to achieve a higher quality of service for the given scenarios.

«Somos petróleo»

OpenAIRE

Drum, Duskin

2017-01-01

Resumen «Somos petróleo» es un experimento de práctica-como-investigación creado para indagar sobre la manera como los norteamericanos conceptualizan sus relaciones con el petróleo. Durante el performance los participantes leyeron en voz alta emulaciones del testimonio diplomático Gwich'in sobre ser pueblo caribú. En las emulaciones, el texto es el mismo salvo que se reemplaza la palabra «caribú» por «petróleo». Los Gwich'in son un pueblo indígena cuyas tierras de origen se sitúan en el nores...

Programmable genetic algorithm IP core for sensing and surveillance applications

Science.gov (United States)

Katkoori, Srinivas; Fernando, Pradeep; Sankaran, Hariharan; Stoica, Adrian; Keymeulen, Didier; Zebulum, Ricardo

2009-05-01

Real-time evolvable systems are possible with a hardware implementation of Genetic Algorithms (GA). We report the design of an IP core that implements a general purpose GA engine which has been successfully synthesized and verified on a Xilinx Virtex II Pro FPGA Device (XC2VP30). The placed and routed IP core has an area utilization of only 13% and clock speed of 50MHz. The GA core can be customized in terms of the population size, number of generations, cross-over and mutation rates, and the random number generator seed. The GA engine can be tailored to a given application by interfacing with the application specific fitness evaluation module as well as the required storage memory (to store the current and new populations). The core is soft in nature i.e., a gate-level netlist is provided which can be readily integrated with the user's system. The GA IP core can be readily used in FPGA based platforms for space and military applications (for e.g., surveillance, target tracking). The main advantages of the IP core are its programmability, small footprint, and low power consumption. Examples of concept systems in sensing and surveillance domains will be presented.

Fish the ChIPs: a pipeline for automated genomic annotation of ChIP-Seq data

Directory of Open Access Journals (Sweden)

Minucci Saverio

2011-10-01

Full Text Available Abstract Background High-throughput sequencing is generating massive amounts of data at a pace that largely exceeds the throughput of data analysis routines. Here we introduce Fish the ChIPs (FC, a computational pipeline aimed at a broad public of users and designed to perform complete ChIP-Seq data analysis of an unlimited number of samples, thus increasing throughput, reproducibility and saving time. Results Starting from short read sequences, FC performs the following steps: 1 quality controls, 2 alignment to a reference genome, 3 peak calling, 4 genomic annotation, 5 generation of raw signal tracks for visualization on the UCSC and IGV genome browsers. FC exploits some of the fastest and most effective tools today available. Installation on a Mac platform requires very basic computational skills while configuration and usage are supported by a user-friendly graphic user interface. Alternatively, FC can be compiled from the source code on any Unix machine and then run with the possibility of customizing each single parameter through a simple configuration text file that can be generated using a dedicated user-friendly web-form. Considering the execution time, FC can be run on a desktop machine, even though the use of a computer cluster is recommended for analyses of large batches of data. FC is perfectly suited to work with data coming from Illumina Solexa Genome Analyzers or ABI SOLiD and its usage can potentially be extended to any sequencing platform. Conclusions Compared to existing tools, FC has two main advantages that make it suitable for a broad range of users. First of all, it can be installed and run by wet biologists on a Mac machine. Besides it can handle an unlimited number of samples, being convenient for large analyses. In this context, computational biologists can increase reproducibility of their ChIP-Seq data analyses while saving time for downstream analyses. Reviewers This article was reviewed by Gavin Huttley, George

IP-10 is a potential biomarker of cystic fibrosis acute pulmonary exacerbations.

Directory of Open Access Journals (Sweden)

George M Solomon

Full Text Available Cystic fibrosis (CF is characterized by acute pulmonary exacerbations (APE. The CF nasal airway exhibits a similar ion transport defect as the lung, and colonization, infection, and inflammation within the nasal passages are common among CF patients. Nasal lavage fluid (NLF is a minimally invasive means to collect upper airway samples.We collected NLF at the onset and resolution of CF APE and compared a 27-plex cytokine profile to stable CF outpatients and normal controls. We also tested IP-10 levels in the bronchoalveolar lavage fluid (BALF of CF patients. Well-differentiated murine sinonasal monolayers were exposed to bacterial stimulus, and IP-10 levels were measured to test epithelial secretion.Subjects hospitalized for APE had elevated IP-10 (2582 pg/mL [95% CL of mean: 818,8165], N=13 which significantly decreased (647 pg/mL [357,1174], P<0.05, N =13 following antimicrobial therapy. Stable CF outpatients exhibited intermediately elevated levels (680 pg/mL [281,1644], N=13 that were less than CF inpatients upon admission (P=0.056 but not significantly different than normal controls (342 pg/mL [110,1061]; P=0.3, N=10. IP-10 was significantly increased in CF BALF (2673 pg/mL [1306,5458], N=10 compared to healthy post-lung transplant patients (8.4 pg/mL [0.03,2172], N=5, P<0.001. IP-10 levels from well-differentiated CF murine nasal epithelial monolayers exposed to Pseudomonas PAO-1 bacteria-free prep or LPS (100 nM apically for 24 hours were significantly elevated (1159 ± 147, P<0.001 for PAO-1; 1373 ± 191, P<0.001 for LPS vs. 305 ± 68 for vehicle controls. Human sino-nasal epithelial cells derived from CF patients had a similar response to LPS (34% increase, P<0.05, N=6.IP-10 is elevated in the nasal lavage of CF patients with APE and responds to antimicrobial therapy. IP-10 is induced by airway epithelia following stimulation with bacterial pathogens in a murine model. Additional research regarding IP-10 as a potential biomarker is

KChIP2 genotype dependence of transient outward current (Ito) properties in cardiomyocytes isolated from male and female mice.

Science.gov (United States)

Waldschmidt, Lara; Junkereit, Vera; Bähring, Robert

2017-01-01

The transient outward current (Ito) in cardiomyocytes is largely mediated by Kv4 channels associated with Kv Channel Interacting Protein 2 (KChIP2). A knockout model has documented the critical role of KChIP2 in Ito expression. The present study was conducted to characterize in both sexes the dependence of Ito properties, including current magnitude, inactivation kinetics, recovery from inactivation and voltage dependence of inactivation, on the number of functional KChIP2 alleles. For this purpose we performed whole-cell patch-clamp experiments on isolated left ventricular cardiomyocytes from male and female mice which had different KChIP2 genotypes; i.e., wild-type (KChIP2+/+), heterozygous knockout (KChIP2+/-) or complete knockout of KChIP2 (KChIP2-/-). We found in both sexes a KChIP2 gene dosage effect (i.e., a proportionality between number of alleles and phenotype) on Ito magnitude, however, concerning other Ito properties, KChIP2+/- resembled KChIP2+/+. Only in the total absence of KChIP2 (KChIP2-/-) we observed a slowing of Ito kinetics, a slowing of recovery from inactivation and a negative shift of a portion of the voltage dependence of inactivation. In a minor fraction of KChIP2-/- myocytes Ito was completely lost. The distinct KChIP2 genotype dependences of Ito magnitude and inactivation kinetics, respectively, seen in cardiomyocytes were reproduced with two-electrode voltage-clamp experiments on Xenopus oocytes expressing Kv4.2 and different amounts of KChIP2. Our results corroborate the critical role of KChIP2 in controlling Ito properties. They demonstrate that the Kv4.2/KChIP2 interaction in cardiomyocytes is highly dynamic, with a clear KChIP2 gene dosage effect on Kv4 channel surface expression but not on inactivation gating.

How to Use FASTLANEs to Protect IP Networks

National Research Council Canada - National Science Library

Robson, Christopher L

2006-01-01

.... By using appropriate configuration and taking full advantage of new IP technologies and successful network encryption FASTLANE devices, interconnecting individual agency networks into a common...

FANCD2 Binds CtIP and Regulates DNA-End Resection during DNA Interstrand Crosslink Repair

Directory of Open Access Journals (Sweden)

Junya Unno

2014-05-01

Full Text Available The Fanconi anemia (FA pathway is critically involved in the maintenance of hematopoietic stem cells and the suppression of carcinogenesis. A key FA protein, FANCD2, is monoubiquitinated and accumulates in chromatin in response to DNA interstrand crosslinks (ICLs, where it coordinates DNA repair through mechanisms that are still poorly understood. Here, we report that CtIP protein directly interacts with FANCD2. A region spanning amino acids 166 to 273 of CtIP and monoubiquitination of FANCD2 are both essential for the FANCD2-CtIP interaction and mitomycin C (MMC-induced CtIP foci. Remarkably, both FANCD2 and CtIP are critical for MMC-induced RPA2 hyperphosphorylation, an event that accompanies end resection of double-strand breaks. Collectively, our results reveal a role of monoubiquitinated FANCD2 in end resection that depends on its binding to CtIP during ICL repair.

Influence of Security Mechanisms on the Quality of Service of VoIP

Science.gov (United States)

Backs, Peter; Pohlmann, Norbert

While Voice over IP (VoIP) is advancing rapidly in the telecommunications market, the interest to protect the data transmitted by this new service is also rising. However, in contrast to other internet services such as email or HTTP, VoIP is real-time media, and therefore must meet a special requirement referred to as Quality-of-Service to provide a comfortable flow of speech. Speech quality is worsened when transmitted over the network due to delays in transmission or loss of packets. Often, voice quality is at a level that even prevents comprehensive dialog. Therefore, an administrator who is to setup a VoIP infrastructure might consider avoiding additional decreases in voice quality resulting from security mechanisms, and might leave internet telephony unprotected as a result. The inspiration for this paper is to illustrate that security mechanisms have negligible impact on speech quality and should in fact be encouraged.

Value-Based Billing in a 3G IP Services Environment

OpenAIRE

Ryan, Conor; Donnelly, William; de Leastar, Eamonn; Cloney, James

2002-01-01

The proliferation of IP-based services has resulted in a paradigm shift away from traditional flat-rat, single service billing to content and usage based billing for composed service sets. The Information Societies Technology (IST) FORM project has prototyped an accounting and billing solution for IP-based telecommunications services. A key element of the solution is the IPDR Network Data Management - Usage specification. This paper presents the FORM development of a federated accounting and ...

TCP/IP Communication System for Controlling a Vehicular Traffic Intersection

Directory of Open Access Journals (Sweden)

Pedraza-Martínez Luis Fernando

2013-10-01

Full Text Available This paper describes the development of a prototype of a vehicular traffic controller, whose system of communication is based on the TCP/IP protocol, in order to re- motely monitor and control the operation of traffic lights for a vehicular intersection. The results show the times of communication between the central and the traffic controller. The conclusions highlight the importance of using the TCP/IP protocol in traffic light systems.

Comparação de hábitos de bem estar vocal entre cantores líricos e populares A comparison between vocal habits of lyric and popular singers

Directory of Open Access Journals (Sweden)

Ana Paula Dassie-Leite

2011-02-01

Full Text Available OBJETIVO: comparar hábitos de bem estar vocal entre cantores líricos e populares. MÉTODOS: foi realizado um trabalho exploratório descritivo, com a participação de 30 cantores líricos e 30 populares, estudantes da Universidade Livre de Música. Todos responderam um questionário com 13 questões objetivas sobre hábitos vocais e utilização profissional da voz. Os dados foram tabulados e analisados estatisticamente RESULTADOS: cantores líricos e populares têm hábitos semelhantes de alimentação, tabagismo, etilismo e uso de drogas recreacionais. Cantores populares têm menos horas de sono/repouso ao dia, sendo esta uma diferença estatisticamente significante. Este grupo também se diferenciou dos cantores líricos por terem, em sua maioria, outro trabalho com a utilização profissional da voz falada. Também foi estatisticamente significante a maior carga horária no uso da voz cantada em líricos, bem como o maior uso de recursos considerados mitos para melhorar a voz. Cantores populares conhecem menos o trabalho fonoaudiológico junto aos profissionais da voz. Os cantores líricos aquecem a voz com maior frequência em relação aos populares, embora este segundo grupo, tenha demonstrado que este hábito tem sido adquirido. Tanto cantores líricos quanto populares não desaquecem a voz sistematicamente, depois da atividade profissional. CONCLUSÃO: Cantores líricos e populares com formação musical específica têm, em geral, hábitos de bem estar vocal semelhantes e diferenciam-se principalmente em relação à carga horária de trabalho semanal, à utilização de mitos na tentativa de melhorar a voz, ao conhecimento sobre o trabalho fonoaudiológico e à prática de aquecimento e desaquecimento vocal.PURPOSE: to compare vocal welfare habits of lyric and popular singers. METHODS: it is a descriptive exploratory work, with the participation of 30 lyrical singers and 30 popular singers. All answered a questionnaire with 13

Potassium Channel Interacting Protein 2 (KChIP2) is not a transcriptional regulator of cardiac electrical remodeling

DEFF Research Database (Denmark)

Winther, Sine V; Tuomainen, Tomi; Borup, Rehannah

2016-01-01

The heart-failure relevant Potassium Channel Interacting Protein 2 (KChIP2) augments CaV1.2 and KV4.3. KChIP3 represses CaV1.2 transcription in cardiomyocytes via interaction with regulatory DNA elements. Hence, we tested nuclear presence of KChIP2 and if KChIP2 translocates into the nucleus...... intracellular Ca(2+) concentration. Neither increasing nor decreasing intracellular Ca(2+) concentrations caused translocation of KChIP2. Microarray analysis did not identify relief of transcriptional repression in murine KChIP2(-/-) heart samples. We conclude that although there is a baseline presence of KCh...

Enginyeria de tràfic en xarxes de transport òptiques per a entorns d'àrea metropolitana (RPR) i de gran abast (ASON)

OpenAIRE

Spadaro, Salvatore

2005-01-01

La arquitectura de las redes de transporte actuales está basada en la tecnología de transporte SDH (Synchronous Digital Hierarchy). Las redes SDH se han diseñado y están optimizadas básicamente para el transporte del tráfico de voz. Actualmente, se está experimentando un crecimiento exponencial del volumen de tráfico de datos. Este crecimiento se debe a que el protocolo IP se está consolidando como capa de integración para servicios múltiples, algunos de ellos con requerimientos de Calidad de...

Análise acústica e perceptivo-auditiva da voz de atores e não atores masculinos: long term average spectrum e o "formante do ator"

OpenAIRE

Master, Suely [UNIFESP

2005-01-01

O conhecimento das diferenças entre as vozes de atores e não atores, nos seus aspectos perceptivos e acústicos - especialmente por meio do Long-term average spectrum - podem contribuir para o re-direcionamento tanto da avaliação quanto da preparação vocal destes que buscam uma técnica vocal econômica e eficiente, os atores. Não há em nosso meio estudos da voz de atores utilizando o LTAS o objetivo do presente estudo é estabelecer as diferenças entre as vozes de atores e não atores nas loudnes...

A novel fusion protein of IP10-scFv retains antibody specificity and chemokine function

Energy Technology Data Exchange (ETDEWEB)

Junqing, Guo; Liu, Chen; Hongwu, Ai; Jiannian, Jing; Jiyong, Zhou; Chuyu, Zhang; Shangyou, You

2004-07-23

We combined the specificity of tumor-specific antibody with the chemokine function of interferon-{gamma} inducible protein 10 (IP-10) to recruit immune effector cells in the vicinity of tumor cells. A novel fusion protein of IP10-scFv was constructed by fusing mouse IP-10 to V{sub H} region of single-chain Fv fragment (scFv) against acidic isoferritin (AIF), and expressed in NS0 murine myeloma cells. The IP10-scFv fusion protein was shown to maintain the specificity of the antiAIF scFv with similar affinity constant, and bind to the human hepatocarcinoma SMMC 7721 cells secreting AIF as well as the activated mouse T lymphocytes expressing CXCR3 receptor. Furthermore, the IP10-scFv protein either in solution or bound on the surface of SMMC 7721 cells induced significant chemotaxis of mouse T cells in vitro. The results indicate that the IP10-scFv fusion protein possesses both bioactivities of the tumor-specific antibody and IP-10 chemokine, suggesting its possibility to induce an enhanced immune response against the residual tumor cells in vivo.

Triazolophostins: a library of novel and potent agonists of IP3 receptors.

Science.gov (United States)

Vibhute, Amol M; Konieczny, Vera; Taylor, Colin W; Sureshan, Kana M

2015-06-28

IP3 receptors are channels that mediate the release of Ca(2+) from the intracellular stores of cells stimulated by hormones or neurotransmitters. Adenophostin A (AdA) is the most potent agonist of IP3 receptors, with the β-anomeric adenine contributing to the increased potency. The potency of AdA and its stability towards the enzymes that degrade IP3 have aroused interest in AdA analogs for biological studies. The complex structure of AdA poses problems that have necessitated optimization of synthetic conditions for each analog. Such lengthy one-at-a-time syntheses limit access to AdA analogs. We have addressed this problem by synthesizing a library of triazole-based AdA analogs, triazolophostins, by employing click chemistry. An advanced intermediate having all the necessary phosphates and a β-azide at the anomeric position was reacted with various alkynes under Cu(i) catalysis to yield triazoles, which upon deprotection gave triazolophostins. All eleven triazolophostins synthesized are more potent than IP3 and some are equipotent with AdA in functional analyses of IP3 receptors. We show that a triazole ring can replace adenine without compromising the potency of AdA and provide facile routes to novel AdA analogs.

Impact of VoIP and QoS on Open and Distance Learning

Directory of Open Access Journals (Sweden)

Sanjay JASOLA

2006-07-01

Full Text Available Voice over Internet Protocol (VoIP is becoming a reality in many organizations. The potential for mobility in voice over wi-fi networks will derive demand for the technology. Wireless VoIP is poised to rival VoIP as an alternative telephony tool. Internet has been used to transport data in the form of packet. In the past, Internet did not support any kind of sophisticated quality of service (QoS mechanism. Although the type of service (TOS field in the Internet protocol (IP header has been existing and has been allowing the differentiated treatment of packets, it was never really used on a large scale. The voice is sensitive to delay and jitter so bandwidth must be guaranteed while transporting it. With the extensive use of Internet for carrying voice, there is a need to add QoS functionality in it. QoS with reference to VoIP has been discussed in the paper. Limited bandwidth and network latency are the issues which need to be considered while using wireless LAN for packetized voice data. Efforts of standards like 802.11e which will take care of these issues, have also been explored. The impact of these technologies on distance education has also been explored in the paper.

DNA-binding proteins regulating pIP501 transfer and replication

Directory of Open Access Journals (Sweden)

Elisabeth Grohmann

2016-08-01

Full Text Available pIP501 is a Gram-positive broad-host-range model plasmid intensively used for studying plasmid replication and conjugative transfer. It is a multiple antibiotic resistance plasmid frequently found in clinical Enterococcus faecalis and Enterococcus faecium isolates. Replication of pIP501 proceeds unidirectionally by a theta mechanism. The minimal replicon of pIP501 is composed of the repR gene encoding the essential rate-limiting replication initiator protein RepR and the origin of replication, oriR, located downstream of repR. RepR is similar to RepE of related streptococcal plasmid pAMβ1, which has been shown to possess RNase activity cleaving free RNA molecules in close proximity of the initiation site of DNA synthesis. Replication of pIP501 is controlled by the concerted action of a small protein, CopR, and an antisense RNA, RNAIII. CopR has a dual role: It acts as transcriptional repressor at the repR promoter and prevents convergent transcription of RNAIII and repR mRNA (RNAII, thereby indirectly increasing RNAIII synthesis. CopR binds asymmetrically as a dimer at two consecutive binding sites upstream of and overlapping with the repR promoter. RNAIII induces transcriptional attenuation within the leader region of the repR mRNA (RNAII. Deletion of either control component causes a 10- to 20-fold increase of plasmid copy number, while simultaneous deletions have no additional effect. Conjugative transfer of pIP501 depends on a type IV secretion system (T4SS encoded in a single operon. Its transfer host-range is considerably broad, as it has been transferred to virtually all Gram-positive bacteria including filamentous streptomycetes and even the Gram-negative Escherichia coli. Expression of the 15 genes encoding the T4SS is tightly controlled by binding of the relaxase TraA, the transfer initiator protein, to the operon promoter, which overlaps with the origin of transfer (oriT. The T4SS operon encodes the DNA-binding proteins TraJ (VirD4

The Verb Always Leaves IP in V2 Clauses

DEFF Research Database (Denmark)

Schwartz, Bonnie D.; Vikner, Sten

2007-01-01

The verb second (V2) phenomenon, as it is found in the Germanic languages, has been the focus of much attention within recent syntactic research. In most of the literature on V2, it is assumed that the verb in all V2 clauses has moved to a head position outside IP, e.g. Cº. In Schwartz & Vikner...... (1989) we claimed that all V2 clauses were CPs, and we referred to this analysis as the 'traditional' analysis. In this paper we shall call it the 'V2 outside IP' analysis, and by using this term we want to convey that although in what follows we will adhere to the view that the verb moves to Cº, any...... analysis in which the verb moves into an Xº which is the sister of IP may be compatible with what we say here. Various alternatives to this analysis have been explored in the literature, and here we will address two in particular: One alternative is that there is an asymmetry between subject...

Bio-EdIP: An automatic approach for in vitro cell confluence images quantification.

Science.gov (United States)

Cardona, Andrés; Ariza-Jiménez, Leandro; Uribe, Diego; Arroyave, Johanna C; Galeano, July; Cortés-Mancera, Fabian M

2017-07-01

Cell imaging is a widely-employed technique to analyze multiple biological processes. Therefore, simple, accurate and quantitative tools are needed to understand cellular events. For this purpose, Bio-EdIP was developed as a user-friendly tool to quantify confluence levels using cell culture images. The proposed algorithm combines a pre-processing step with subsequent stages that involve local processing techniques and a morphological reconstruction-based segmentation algorithm. Segmentation performance was assessed in three constructed image sets, comparing F-measure scores and AUC values (ROC analysis) for Bio-EdIP, its previous version and TScratch. Furthermore, segmentation results were compared with published algorithms using eight public benchmarks. Bio-EdIP automatically segmented cell-free regions from images of in vitro cell culture. Based on mean F-measure scores and ROC analysis, Bio-EdIP conserved a high performance regardless of image characteristics of the constructed dataset, when compared with its previous version and TScratch. Although acquisition quality of the public dataset affected Bio-EdIP segmentation, performance was better in two out of eight public sets. Bio-EdIP is a user-friendly interface, which is useful for the automatic analysis of confluence levels and cell growth processes using in vitro cell culture images. Here, we also presented new manually annotated data for algorithms evaluation. Copyright © 2017 Elsevier B.V. All rights reserved.

The Spacelab IPS Star Simulator

Science.gov (United States)

Wessling, Francis C., III

The cost of doing business in space is very high. If errors occur while in orbit the costs grow and desired scientific data may be corrupted or even lost. The Spacelab Instrument Pointing System (IPS) Star Simulator is a unique test bed that allows star trackers to interface with simulated stars in a laboratory before going into orbit. This hardware-in-the loop testing of equipment on earth increases the probability of success while in space. The IPS Star Simulator provides three fields of view 2.55 x 2.55 degrees each for input into star trackers. The fields of view are produced on three separate monitors. Each monitor has 4096 x 4096 addressable points and can display 50 stars (pixels) maximum at a given time. The pixel refresh rate is 1000 Hz. The spectral output is approximately 550 nm. The available relative visual magnitude range is 2 to 8 visual magnitudes. The star size is less than 100 arc seconds. The minimum star movement is less than 5 arc seconds and the relative position accuracy is approximately 40 arc seconds. The purpose of this paper is to describe the LPS Star Simulator design and to provide an operational scenario so others may gain from the approach and possible use of the system.

Dental anomalies in 14 patients with IP: clinical and radiological analysis and review.

Science.gov (United States)

Santa-Maria, Fernanda D; Mariath, Luiza Monteavaro; Poziomczyk, Cláudia S; Maahs, Marcia A P; Rosa, Rafael F M; Zen, Paulo R G; Schüller-Faccini, Lavínia; Kiszewski, Ana Elisa

2017-06-01

Current knowledge on dental anomalies in patients with incontinentia pigmenti (IP) has been obtained by examining case reports; however, an overall characterization of such alterations remains lacking. The objective of this study was to determine the frequency, type and location of dental alterations in IP using a case series. Fourteen patients (9 children and 5 adults) with a clinical diagnosis of IP who presented dental anomalies were included in this study. All patients were administered a clinical questionnaire, dental examination and radiological investigation. In the present case series, agenesis of primary dentition was present in 60 % of patients and agenesis of permanent tooth was present in 92.8 % of patients. Most cases were missing at least 6 teeth. Second molar agenesis was present in 13 patients (92.8 %). Anomalies in dental crowns occurred in 71.4 % of cases, and the central incisor was most frequently affected. Two adult patients still had primary teeth. Malocclusion was found in 10 patients (71.4 %). High-arched palate was observed in 7 (50 %) patients. Patients with IP present alterations in both primary and permanent dentition. Because the agenesis of permanent teeth is more common, primary teeth are not always replaced. In addition, the durability of primary dentition appears to be greater in IP. This study shows that patients with IP experience significant loss of teeth, especially in permanent dentition, and have an increased risk of high-arched palate compared to the general population. Prophylactic care of primary teeth in IP is relevant for improving functional and aesthetic outcomes until dental prostheses are implanted.

Pre-equilibrium Longitudinal Flow in the IP-Glasma Framework for Pb+Pb Collisions at the LHC

Science.gov (United States)

McDonald, Scott; Shen, Chun; Fillion-Gourdeau, François; Jeon, Sangyong; Gale, Charles

2017-08-01

In this work, we debut a new implementation of IP-Glasma and quantify the pre-equilibrium longitudinal flow in the IP-Glasma framework. The saturation physics based IP-Glasma model naturally provides a non-zero initial longitudinal flow through its pre-equilibrium Yang-Mills evolution. A hybrid IP-Glasma+MUSIC+UrQMD frame-work is employed to test this new implementation against experimental data and to make further predictions about hadronic flow observables in Pb+Pb collisions at 5.02 TeV. Finally, the non-zero pre-equilibrium longitudinal flow of the IP-Glasma model is quantified, and its origin is briefly discussed.

IP-10 can be measured in dried plasma spots in patients with chronic hepatitis C infection

DEFF Research Database (Denmark)

Ruhwald, Morten; Andersen, Ellen Sloth; Christensen, Peer Brehm

2012-01-01

The chemokine IP-10 (CXCL10) is a candidate marker for hepatitis C virus (HCV) fibrosis monitoring. The aim of this proof-of-concept study is to assess if IP-10 measurements from dried plasma spots (DPS) are accurate in HCV-infected patients with either minimal or significant fibrosis. We measured...... IP-10 levels in plasma and DPS of 21 HCV-infected patients with cirrhosis and 19 patients with no/little fibrosis (determined with FibroScan). Cirrhotic patients had significantly higher levels of IP-10 compared to patients with minimal fibrosis. DPS and plasma measurements of IP-10 are comparable...

Legal Protection on IP Cores for System-on-Chip Designs

Science.gov (United States)

Kinoshita, Takahiko

The current semiconductor industry has shifted from vertical integrated model to horizontal specialization model in term of integrated circuit manufacturing. In this circumstance, IP cores as solutions for System-on-Chip (SoC) have become increasingly important for semiconductor business. This paper examines to what extent IP cores of SoC effectively can be protected by current intellectual property system including integrated circuit layout design law, patent law, design law, copyright law and unfair competition prevention act.

PERBANDINGAN KINERJA IP SEC DAN SSL

Directory of Open Access Journals (Sweden)

Dessyanto Boedi P

2015-04-01

Full Text Available Ipsec (IP Security and SSL (Secure Socket Layer is the most widely used techniques to secure data communications over the Internet. Both of these techniques has advantages and disadvantages of each. The purpose of this study is to present an analysis of the two techniques above in terms of security and performance.

[Clinical application of IPS-empress 2 pressable all-ceramic crowns].

Science.gov (United States)

Wang, Ai-jun; He, Xiao-ming; Liu, Li-xia; Zhang, Chao-biao; Zhang, Min; Shen, Bei-yong

2007-02-01

To evaluate the clinical prosthetic effect of IPS-Empress 2 pressahie ceramic crowns. 198 teeth of 70 patients were restored with IPS-Empress 2 pressahie ceramic crowns. The patients were asked to return in one week and every half year. The clinical prosthetic effect was evaluated. Through follow-up of 3-38 months, the veneer porcelain crowns of 3 teeth were broken. 2 crowns fall off due to teeth fracture, gingivitis occurred in 2 teeth, pulpitis or periapical periodontitis occurred in 3 teeth. The shades of 3 crowns were darkening. The prosthetic effect of 185 teeth was satisfied. The rate of satisfaction was 93.4%. IPS-Empress 2 pressable all-ceramic crown has the advantages of aesthetic effect, good hiocompatihility and simple fabrication. But its strength is not enough for posterior teeth and it can not cover the deep color of non-vital teeth and metal materials.

Human iPS Cell-Derived Germ Cells: Current Status and Clinical Potential

Directory of Open Access Journals (Sweden)

Tetsuya Ishii

2014-10-01

Full Text Available Recently, fertile spermatozoa and oocytes were generated from mouse induced pluripotent (iPS cells using a combined in vitro and in vivo induction system. With regard to germ cell induction from human iPS cells, progress has been made particularly in the male germline, demonstrating in vitro generation of haploid, round spermatids. Although iPS-derived germ cells are expected to be developed to yield a form of assisted reproductive technology (ART that can address unmet reproductive needs, genetic and/or epigenetic instabilities abound in iPS cell generation and germ cell induction. In addition, there is still room to improve the induction protocol in the female germline. However, rapid advances in stem cell research are likely to make such obstacles surmountable, potentially translating induced germ cells into the clinical setting in the immediate future. This review examines the current status of the induction of germ cells from human iPS cells and discusses the clinical potential, as well as future directions.

DIVERSITY in binding, regulation, and evolution revealed from high-throughput ChIP.

Science.gov (United States)

Mitra, Sneha; Biswas, Anushua; Narlikar, Leelavati

2018-04-23

Genome-wide in vivo protein-DNA interactions are routinely mapped using high-throughput chromatin immunoprecipitation (ChIP). ChIP-reported regions are typically investigated for enriched sequence-motifs, which are likely to model the DNA-binding specificity of the profiled protein and/or of co-occurring proteins. However, simple enrichment analyses can miss insights into the binding-activity of the protein. Note that ChIP reports regions making direct contact with the protein as well as those binding through intermediaries. For example, consider a ChIP experiment targeting protein X, which binds DNA at its cognate sites, but simultaneously interacts with four other proteins. Each of these proteins also binds to its own specific cognate sites along distant parts of the genome, a scenario consistent with the current view of transcriptional hubs and chromatin loops. Since ChIP will pull down all X-associated regions, the final reported data will be a union of five distinct sets of regions, each containing binding sites of one of the five proteins, respectively. Characterizing all five different motifs and the corresponding sets is important to interpret the ChIP experiment and ultimately, the role of X in regulation. We present diversity which attempts exactly this: it partitions the data so that each partition can be characterized with its own de novo motif. Diversity uses a Bayesian approach to identify the optimal number of motifs and the associated partitions, which together explain the entire dataset. This is in contrast to standard motif finders, which report motifs individually enriched in the data, but do not necessarily explain all reported regions. We show that the different motifs and associated regions identified by diversity give insights into the various complexes that may be forming along the chromatin, something that has so far not been attempted from ChIP data. Webserver at http://diversity.ncl.res.in/; standalone (Mac OS X/Linux) from https

SignalSpider: Probabilistic pattern discovery on multiple normalized ChIP-Seq signal profiles

KAUST Repository

Wong, Kachun; Li, Yue; Peng, Chengbin; Zhang, Zhaolei

2014-01-01

Motivation: Chromatin immunoprecipitation (ChIP) followed by high-throughput sequencing (ChIP-Seq) measures the genome-wide occupancy of transcription factors in vivo. Different combinations of DNA-binding protein occupancies may result in a gene

Immunocytochemical evidence for co-expression of Type III IP3 receptor with signaling components of bitter taste transduction

Directory of Open Access Journals (Sweden)

Kinnamon Sue C

2001-04-01

Full Text Available Abstract Background Taste receptor cells are responsible for transducing chemical stimuli into electrical signals that lead to the sense of taste. An important second messenger in taste transduction is IP3, which is involved in both bitter and sweet transduction pathways. Several components of the bitter transduction pathway have been identified, including the T2R/TRB taste receptors, phospholipase C β2, and the G protein subunits α-gustducin, β3, and γ13. However, the identity of the IP3 receptor subtype in this pathway is not known. In the present study we used immunocytochemistry on rodent taste tissue to identify the IP3 receptors expressed in taste cells and to examine taste bud expression patterns for IP3R3. Results Antibodies against Type I, II, and III IP3 receptors were tested on sections of rat and mouse circumvallate papillae. Robust cytoplasmic labeling for the Type III IP3 receptor (IP3R3 was found in a large subset of taste cells in both species. In contrast, little or no immunoreactivity was seen with antibodies against the Type I or Type II IP3 receptors. To investigate the potential role of IP3R3 in bitter taste transduction, we used double-label immunocytochemistry to determine whether IP3R3 is expressed in the same subset of cells expressing other bitter signaling components. IP3R3 immunoreactive taste cells were also immunoreactive for PLCβ2 and γ13. Alpha-gustducin immunoreactivity was present in a subset of IP3R3, PLCβ2, and γ13 positive cells. Conclusions IP3R3 is the dominant form of the IP3 receptor expressed in taste cells and our data suggest it plays an important role in bitter taste transduction.

Synthesis and evaluation of p-iodo-phentermine (IP) as a brain perfusion imaging agent

International Nuclear Information System (INIS)

Kizuka, H.; Elmaleh, D.R.; Brownell, G.L.; Strauss, H.W.

1985-01-01

rho-( 123 I and 131 I) iodo α,α-dimethylphenethylamine (rho-iodophentermine, IP) as the α-methylated analogue of iodoamphetamine has been prepared. It is hoped that this methyl substitution will increase the lipophilicity of the agent, enhance resistance to metabolism by monoamine oxidase, and will result in increased initial uptake and slower washout from the brain as compared to N-isopropyl-rho-( 123 I) iodoamphetamine. IP was prepared by diazotization of rho-aminophentermine followed by decomposition of the diazonium salt with KI. Radioiodinated IP was prepared either by the solid-phase isotopic exchange reaction or by decomposition of the piperidinotriazene derivative with a radiochemical yield of 40-60%. Biodistribution of 131 I-IP in rats showed brain uptake in the range of 1.7% dose g -1 at 5, 30 and 60 min. Imaging studies with 123 I-IP in dogs showed high brain extraction and slow washout of activity. (author)

Using the MDCT thick slab MinIP method for the follow-up of pulmonary emphysema.

Science.gov (United States)

Lan, Hai; Nishitani, Hiromu; Nishihara, Sadamitsu; Ueno, Junji; Takao, Shoichiro; Iwamoto, Seiji; Kawanaka, Takashi; Mahmut, Mawlan; Qingge, Si

2011-08-01

The purpose of this study was to evaluate the usefulness of thick slab minimum intensity projection (MinIP) as a follow-up method in patients with pulmonary emphysema. This method was used to determine the presence or absence of changes over time in the lung field based on multi-detector-row CT (MDCT) data. Among patients diagnosed with pulmonary emphysema who underwent 16-MDCT (slice thickness, 1 mm) twice at an interval of 6 months or more, 12 patients without changes in the lung field and 14 with clear changes in the lung field were selected as subjects. An image interpretation experiment was performed by five image interpreters. Pulmonary emphysema was followed up using two types of thick slab MinIP (thick slab MinIP 1 and 2) and multi-planar reformation (MPR), and the results of image interpretation were evaluated by receiver operating characteristic (ROC) analysis. In addition, the time required for image interpretation was compared among the three follow-up methods. The area under the ROC curve (Az) was 0.794 for thick slab MinIP 1, 0.778 for the thick slab MinIP 2, and 0.759 for MPR, showing no significant differences among the three methods. Individual differences in each item were significantly more marked for MPR than for thick slab MinIP. The time required for image interpretation was around 18 seconds for thick slab MinIP 1, 11 seconds for thick slab MinIP 2, and approximately 127 seconds for MPR, showing significant differences among the three methods. There were no significant differences in the results of image interpretation regarding the presence or absence of changes in the lung fields between thick slab MinIP and MPR. However, thick slab MinIP showed a shorter image interpretation time and smaller individual differences in the results among image interpreters than MPR, suggesting the usefulness of this method for determining the presence or absence of changes with time in the lung fields of patients with pulmonary emphysema.

An Installation of IPS Bypass Line at the Fuel Test Loop

Energy Technology Data Exchange (ETDEWEB)

Choi, Ho Young; Ahn, G. H.; Lee, M.; Kim, M. S.; Cho, S. H.; Han, J. S.; Hur, S. O. [KAERI, Daejeon (Korea, Republic of)

2010-12-15

The Fuel Test Loop(FTL) was installed for the national goal of self-supporting technology in the field of design and construction of nuclear power plant. The FTL with the fuel irradiation equipment is essential in developing, improving and inspecting the fuel of CANDU type or PWR type nuclear power plant. The FTL should be operated at the same conditions of commercial nuclear power plant such as temperature, pressure, flow rate, neutron flux and so on. Starting designing in December 2001, the FTL was installed from March 2007 to August 2008. Especially the In Pile Section(IPS) was installed at IR1 hole in August 2008. Until September 2009 after loading the test fuel, a series of power escalation tests (LSD, CSB1, CSB2, HSB, HOP) were conducted. And it was operated at the condition of CSB2 for the 8 cycles from October 2009 to July 2010. But it could not be normally operated in early 2010, because the high radiation released from irradiated materials due to the worn down bearing of main cooling pump. So, we removed the IPS and installed a newly designed IPS bypass line to prevent increasing high radiation. In this report we will present preliminary works, main works processes, devices of making work environments, a designing and manufacturing of IPS bypass line and a rack of IPS, installing know-hows, problems and solutions broke out during the work etc. We believe that our efforts to complete successful installing and operating of the FTL system will contribute for the efficient utilization of HANARO

Protocol: methodology for chromatin immunoprecipitation (ChIP in Chlamydomonas reinhardtii

Directory of Open Access Journals (Sweden)

Strenkert Daniela

2011-11-01

Full Text Available Abstract We report on a detailed chromatin immunoprecipitation (ChIP protocol for the unicellular green alga Chlamydomonas reinhardtii. The protocol is suitable for the analysis of nucleosome occupancy, histone modifications and transcription factor binding sites at the level of mononucleosomes for targeted and genome-wide studies. We describe the optimization of conditions for crosslinking, chromatin fragmentation and antibody titer determination and provide recommendations and an example for the normalization of ChIP results as determined by real-time PCR.

TCP/IP Network Administration

CERN Document Server

Hunt, Craig

2002-01-01

This complete guide to setting up and running a TCP/IP network is essential for network administrators, and invaluable for users of home systems that access the Internet. The book starts with the fundamentals -- what protocols do and how they work, how addresses and routing are used to move data through the network, how to set up your network connection -- and then covers, in detail, everything you need to know to exchange information via the Internet. Included are discussions on advanced routing protocols (RIPv2, OSPF, and BGP) and the gated software package that implements them, a tutorial

Quantitative analysis of intraneuronal transport in human iPS neurons

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Haruko Nakamura

2015-08-01

Full Text Available Induced pluripotent stem (iPS cells are promising tools to investigate disease mechanism and develop new drugs. Intraneuronal transport, which is fundamental for neuronal survival and function, is vulnerable to various pharmacological and chemical agents and is disrupted in some neurodegenerative disorders. We applied a quantification method for axonal transport by counting CM-DiI–labeled particles traveling along the neurite, which allowed us to monitor and quantitate, for the first time, intraneuronal transport in human neurons differentiated from iPS cells (iCell neurons. We evaluated the acute effects of several anti-neoplastic agents that have been previously shown to affect intraneuronal transport. Vincristine, paclitaxel and oxaliplatin decreased the number of moving particle along neurites. Cisplatin, however, produced no effect on intraneuronal transport, which is in contrast to our previous report indicating that it inhibits transport in chick dorsal root ganglion neurons. Our system may be a useful method for assessing intraneuronal transport and neurotoxicity in human iPS neurons.

A short-term clinical evaluation of IPS Empress 2 crowns.

Science.gov (United States)

Toksavul, Suna; Toman, Muhittin

2007-01-01

The aim of this study was to evaluate the clinical performance of all-ceramic crowns made with the IPS Empress 2 system after an observation period of 12 to 60 months. Seventy-nine IPS Empress 2 crowns were placed in 21 patients. The all-ceramic crowns were evaluated clinically, radiographically, and using clinical photographs. The evaluations took place at baseline (2 days after cementation) and at 6-month intervals for 12 to 60 months. Survival rate of the crowns was determined using Kaplan-Meier statistical analysis. Based on the US Public Health Service criteria, 95.24% of the crowns were rated satisfactory after a mean follow-up period of 58 months. Fracture was registered in only 1 crown. One endodontically treated tooth failed as a result of fracture at the cervical margin area. In this in vivo study, IPS Empress 2 crowns exhibited a satisfactory clinical performance during an observation period ranging from 12 to 60 months.

[Microstructure and mechanical property of a new IPS-Empress 2 dental glass-ceramic].

Science.gov (United States)

Luo, Xiao-ping; Watts, D C; Wilson, N H F; Silsons, N; Cheng, Ya-qin

2005-03-01

To investigate the microstructure and mechanical properties of a new IPS-Empress 2 dental glass-ceramic. AFM, SEM and XRD were used to analyze the microstructure and crystal phase of IPS-Empress 2 glass-ceramic. The flexural strength and fracture toughness were tested using 3-point bending method and indentation method respectively. IPS-Empress 2 glass-ceramic mainly consisted of lithium disilicate crystal, lithium phosphate and glass matrix, which formed a continuous interlocking structure. The crystal phases were not changed before and after hot-pressed treatment. AFM showed nucleating agent particles of different sizes distributed on the highly polished ceramic surface. The strength and fracture toughness were 300 MPa and 3.1 MPam(1/2). The high strength and fracture toughness of IPS-Empress 2 glass ceramic are attributed to the fine lithium disilicate crystalline, interlocking microstructure and crack deflection.

Compact Modbus TCP/IP protocol for data acquisition systems based on limited hardware resources

Science.gov (United States)

Bai, Q.; Jin, B.; Wang, D.; Wang, Y.; Liu, X.

2018-04-01

The Modbus TCP/IP has been a standard industry communication protocol and widely utilized for establishing sensor-cloud platforms on the Internet. However, numerous existing data acquisition systems built on traditional single-chip microcontrollers without sufficient resources cannot support it, because the complete Modbus TCP/IP protocol always works dependent on a full operating system which occupies abundant hardware resources. Hence, a compact Modbus TCP/IP protocol is proposed in this work to make it run efficiently and stably even on a resource-limited hardware platform. Firstly, the Modbus TCP/IP protocol stack is analyzed and the refined protocol suite is rebuilt by streamlining the typical TCP/IP suite. Then, specific implementation of every hierarchical layer is respectively presented in detail according to the protocol structure. Besides, the compact protocol is implemented in a traditional microprocessor to validate the feasibility of the scheme. Finally, the performance of the proposed scenario is assessed. The experimental results demonstrate that message packets match the frame format of Modbus TCP/IP protocol and the average bandwidth reaches to 1.15 Mbps. The compact protocol operates stably even based on a traditional microcontroller with only 4-kB RAM and 12-MHz system clock, and no communication congestion or frequent packet loss occurs.

A voz de gestores municipais sobre o acesso à saúde nas práticas de gestão

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Bela Feiman Sapiertein Silva

2013-08-01

Full Text Available O acesso universal aos serviços de saúde é um desafio para a gestão municipal numa sociedade em que apresenta a saúde como mercadoria e privilegia o indivíduo consumidor em detrimento do cidadão. O estudo teve como objetivo reconhecer as representações sociais presentes na narrativa das práticas dos gestores municipais de saúde de uma microrregião do sudeste do Brasil sobre o acesso aos serviços de saúde. Trata-se de pesquisa qualitativa mediante entrevista com 16 gestores. Na análise, utilizou-se a técnica do Discurso do Sujeito Coletivo, com o auxílio do programa Qualiquantisoft. Identificaram-se quatro Ideias Centrais: articulação interfederativa; reorganização da porta de entrada; atendimento ao usuário; e, fragilidade para a garantia de acesso. Constatou-se que a qualidade, resolutividade, aproximação com as necessidades do usuário e organização das redes de atenção são pouco expressas, o que reflete um entendimento que não leva em consideração o 'acesso de qualidade e resolutivo'. Compreende-se que a impotência apresentada pelos gestores para gerar mudanças e a falta de participação da sociedade e dos trabalhadores na gestão fortalecem a supremacia dos interesses do mercado e contribuem para a garantia de um 'acesso limitado' e a manutenção do modelo de atenção hegemônico.

Leukotriene B4 (LTB4) induces formation of inositol-phosphates (IP's) in rat peritoneal polymorphonuclear leukocytes (PMN's)

International Nuclear Information System (INIS)

Chi-Rosso, G.; Crooke, S.T.; Mong, S.

1986-01-01

LTB 4 induced rapid breakdown of prelabeled inositol-phospholipids (PI) in rat PMN. Formation of [ 3 H]-inositol-trisphosphate ([ 3 H]-IP 3 ) was rapid, with a peak of 250-300% of the control level, after 5-15 sec of stimulation with LTB 4 . Accumulation of [ 3 H]-inositol-bisphosphate ([ 3 H]-IP 2 ) was rapid, peaking after 30 sec of stimulation. [ 3 H]-inositol-monophosphate ([ 3 H]-IP 1 ) accumulated gradually in the presence of LiCl. The kinetics of [ 3 H]-IP 3 , [ 3 H]-IP 2 and [ 3 H]-IP 1 accumulation suggested that LTB 4 may interact with receptors in PMNs, activate phospholipase C which, in turn, induces hydrolysis of PI. The agonist activities of several LTB 4 analogs were employed to investigate the structure activity relationship of LTB 4 receptor mediated activation of PI hydrolysis. Increases in [ 3 H]-IP 3 formation were dependent upon the concentration of LTB 4 and the agonist analogs. The rank order potency of these analogs were equivalent to that of the pharmacological activity of LTB 4 agonists in the chemotaxis assay. Furthermore, the Islet activation protein (IAP) inhibited LTB 4 induced [ 3 H]-IP 3 formation. The tumor promoting phorbomyristate ester also inhibited LTB 4 induced [ 3 H]-IP 3 formation. These results suggest LTB 4 may interact with receptors in rat PMNs, activate G/sub i/ protein regulated phospholipase C and induce [ 3 H]-IP 3 formation

A educação vocal na infância: a importância da voz no currículo da Educação Infantil na Galiza

OpenAIRE

CASAL DE LA FUENTE, LUCIA

2014-01-01

Publicación derivada da Memoria para a Colación do Grao en Licenciada en Psicopedagoxía "A formación vocal na Educación Infantil" VII Colóquio Luso-Brasileiro & I Colóquio Luso-Afro-Brasileiro de Questões Curriculares Diversos são os trabalhos que envolvem as dificuldades que tem o professorado no momento de controlar a emissão fluída e sã da sua voz (Segura, 2009; Fiuza, 1996), arma principal para o exercício do seu labor diário. Isto pode ser explicado, em parte, pela ausente ou...

Efeito do ruído na voz de educadoras de instituições de educação infantil

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Marcia Simões-Zenari

2012-08-01

Full Text Available OBJETIVO: Avaliar a associação entre níveis de ruído presentes em centros de educação infantil e alterações vocais em educadoras. MÉTODOS: Estudo transversal com 28 educadoras de três instituições de educação infantil de São Paulo, SP, em 2009. Os níveis de pressão sonora foram mensurados segundo a Associação Brasileira de Normas Técnicas, com uso de medidor de nível de pressão sonora. As médias foram classificadas de acordo com os níveis de conforto, desconforto e dano auditivo propostos pela Organização Panamericana de Saúde. As educadoras tiveram a voz avaliada com: autoavaliação com escala analógica visual, avaliação perceptivo-auditiva com escala GRBAS e análise acústica com o programa Praat. Estatística descritiva e teste do qui-quadrado, com 10% de significância devido ao tamanho da amostra, foram usados para análise da associação entre ruído e avaliação vocal. RESULTADOS: As educadoras possuíam idades entre 21 e 56 anos. A média de ruído foi 72,7 dB, considerado dano 2. A autoavaliação vocal das profissionais apresentou média de 5,1 na escala, considerada alteração moderada. Na avaliação perceptivo-auditiva, 74% apresentaram alteração vocal, principalmente rouquidão; destas, 52% foram consideradas alterações leves. A maior parte apresentou frequência fundamental abaixo do esperado na avaliação acústica. Médias de jitter, shimmer e proporção harmônico-ruído estavam alteradas. Presença de ruído entre os harmônicos associou-se a alteração vocal. CONCLUSÕES: Há associação entre presença de ruído entre harmônicos e alteração vocal, com elevados níveis de ruído. Apesar de a maioria das educadoras ter apresentado voz alterada em grau leve, a autoavaliação mostrou alteração moderada, provavelmente pela dificuldade de projeção.

Perfil da saúde vocal de cantores amadores de igreja evangélica Vocal health profile of amateur singers from an evangelical church

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Thaise Marcela Mota Barreto

2011-06-01

Full Text Available OBJETIVO: Investigar o perfil de saúde vocal de cantores amadores de louvores evangélicos com relação a queixas, hábitos e dificuldades vocais vivenciados durante a prática do canto em indivíduos dos gêneros masculino e feminino. MÉTODOS: Participaram 55 sujeitos, com idade entre 18 e 50 anos, os quais responderam a um questionário auto-aplicável sobre identificação de hábitos vocais e possíveis queixas de voz falada e cantada. RESULTADOS: Os cantores religiosos evangélicos amadores relataram queixas relacionadas à voz, tais como rouquidão constante (43,6%, pigarro constante (43,6%, falhas na voz (34,5%, perda de voz (18,1%, garganta seca (18,1%, voz fraca (14,5% e dor no pescoço e na nuca (12,7%. Durante a atividade de canto, as queixas mais reportadas foram as de dificuldades de alcançar notas agudas (45,4%, rouquidão (30,9% e falhas na voz (29%. Os hábitos vocais expostos pelos cantores foram os relativos a falar muito (63,6%, ingerir gelado habitualmente em excesso (43,6%, falar alto (40% e gritar com frequência (20%. Com relação à variável gênero, foram observadas diferenças significativas entre os grupos, relacionadas às variáveis falhas na voz, consumo de gelados e falar alto. CONCLUSÃO: Os cantores religiosos amadores, de ambos os gêneros, apresentam percentual expressivo de queixas e hábitos vocais que podem estar associados à falta de informações sobre os hábitos saudáveis de produção vocal e que podem contribuir para o desenvolvimento de alterações laríngeas e disfonia.PURPOSE: To investigate the vocal health profile of male and female gospel amateur singers regarding vocal complaints, habits and difficulties during singing practice. METHODS: Participants were 55 subjects with ages between 18 and 50 years, who answered a self-assessment questionnaire regarding the identification of vocal habits and possible complaints of spoken and sung voice. RESULTS: Amateur gospel singers reported vocal

Dietary Chemoprevention of PhIP Induced Carcinogenesis in Male Fischer 344 Rats with Tomato and Broccoli

Science.gov (United States)

Canene-Adams, Kirstie; Sfanos, Karen S.; Liang, Chung-Tiang; Yegnasubramanian, Srinivasan; Nelson, William G.; Brayton, Cory; De Marzo, Angelo M.

2013-01-01

The heterocyclic amine, 2-amino-1-methyl-6-phenylimidazo[4,5-B]pyridine (PhIP), found in meats cooked at high temperatures, has been implicated in epidemiological and rodent studies for causing breast, prostate, and colorectal cancers. A previous animal study using a xenograft model has shown that whole tomato and broccoli, when eaten in combination, exhibit a marked effect on tumor reduction compared to when eaten alone. Our aim was to determine if PhIP-induced carcinogenesis can be prevented by dietary consumption of whole tomato + broccoli powders. Male Fischer 344 rats (n = 45) were randomized into the following treatment groups: control (AIN93G diet), PhIP (200 ppm in AIN93G diet for the first 20 weeks of the study), or tomato + broccoli + PhIP (mixed in AIN93G diet at 10% each and fed with PhIP for 20 weeks, and then without PhIP for 32 weeks). Study animals were monitored for 52 weeks and were euthanized as necessary based on a set of criteria for health status and tumor burden. Although there appeared to be some hepatic and intestinal toxicity due to the combination of PhIP and tomato + broccoli, these rodents had improved survival and reduced incidence and/or severity of PhIP-induced neoplastic lesions compared to the PhIP-alone treated group. Rats eating tomato + broccoli exhibited a marked decrease in the number and size of cribiform prostatic intraepitheilial neoplasia/carcinoma in situ (cribiform PIN/CIS) lesions and in the incidence of invasive intestinal adenocarcinomas and skin carcinomas. Although the apparent toxic effects of combined PhIP and tomato + broccoli need additional study, the results of this study support the hypothesis that a diet rich in tomato and broccoli can reduce or prevent dietary carcinogen-induced cancers. PMID:24312188

Normalization and experimental design for ChIP-chip data

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Alekseyenko Artyom A

2007-06-01

Full Text Available Abstract Background Chromatin immunoprecipitation on tiling arrays (ChIP-chip has been widely used to investigate the DNA binding sites for a variety of proteins on a genome-wide scale. However, several issues in the processing and analysis of ChIP-chip data have not been resolved fully, including the effect of background (mock control subtraction and normalization within and across arrays. Results The binding profiles of Drosophila male-specific lethal (MSL complex on a tiling array provide a unique opportunity for investigating these topics, as it is known to bind on the X chromosome but not on the autosomes. These large bound and control regions on the same array allow clear evaluation of analytical methods. We introduce a novel normalization scheme specifically designed for ChIP-chip data from dual-channel arrays and demonstrate that this step is critical for correcting systematic dye-bias that may exist in the data. Subtraction of the mock (non-specific antibody or no antibody control data is generally needed to eliminate the bias, but appropriate normalization obviates the need for mock experiments and increases the correlation among replicates. The idea underlying the normalization can be used subsequently to estimate the background noise level in each array for normalization across arrays. We demonstrate the effectiveness of the methods with the MSL complex binding data and other publicly available data. Conclusion Proper normalization is essential for ChIP-chip experiments. The proposed normalization technique can correct systematic errors and compensate for the lack of mock control data, thus reducing the experimental cost and producing more accurate results.

Extraction of Electronic Evidence from VoIP: Forensic Analysis of A Virtual Hard Disk Vs RAM

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david irwin

2011-03-01

Full Text Available The popularity of Voice over the Internet Protocol (VoIP is increasing as the cost savings and ease of use is realised by a wide range of home and corporate users. However, the technology is also attractive to criminals. This is because VoIP is a global telephony service, in which it is difficult to verify the user’s identification. The security of placing such calls may also be appealing to criminals, as many implementations use strong encryption to secure both the voice payload as well as to control messages making monitoring such VoIP calls difficult since conventional methods such as wire-tapping is not applicable to VoIP calls. Therefore, other methods of recovering electronic evidence and information from VoIP are required.  This research looks at what protocol evidence remains after a VoIP call has taken place examining both a virtual hard disk and the Random Access Memory (RAM. This paper proposes a set of identifiable credentials based on packet header information contained within the VoIP protocol stack. A series of controlled tests were undertaken whereby these credentials were forensically searched for on a virtual machine which was used to make the VoIP call. This experiment was then repeated by a search for the same protocol credentials within the RAM.

A Study on IP Network Recovery through Routing Protocols

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K. Karthik

2016-09-01

Full Text Available Internet has taken major role in our communication infrastructure. Such that requirement of internet availability and reliability has increasing accordingly. The major network failure reasons are failure of node and failure of link among the nodes. This can reduce the performance of major applications in an IP networks. The network recovery should be fast enough so that service interruption of link or node failure. The new path taken by the diverted traffic can be computed either at the time of failures or before failures. These mechanisms are known as Reactive and Proactive protocols respectively. In this paper, we surveyed reactive and proactive protocols mechanisms for IP network recovery.

Experimental evaluation of the IP multimedia subsystem

NARCIS (Netherlands)

Oredope, A.; Liotta, A.; Yang, K.; Tyrode-Goilo, D.H.; Magedanz, T.; Mauro Madeira, E.R.M.; Dini, P.

2005-01-01

The IP Multimedia Subsystem (IMS) is the latest framework for a seamless conversion of the ordinary Internet with mobile cellular systems. As such it has the backing of all major companies since it aims to offer a unified solution to integrated mobile services, including mechanisms for security,

Changepoint detection techniques for VoIP traffic

NARCIS (Netherlands)

Mandjes, M.; Zuraniewski, P.W.

2013-01-01

The control of communication networks critically relies on procedures capable of detecting unanticipated load changes. In this chapter we present an overview of such techniques, in a setting in which each connection consumes roughly the same amount of bandwidth (with VoIP as a leading example). For

Changepoint Detection Techniques for VoIP Traffic

NARCIS (Netherlands)

Mandjes, M.; Żuraniewski, P.; Biersack, E.; Callegari, C.; Matijasevic, M.

2013-01-01

The control of communication networks critically relies on procedures capable of detecting unanticipated load changes. In this chapter we present an overview of such techniques, in a setting in which each connection consumes roughly the same amount of bandwidth (with VoIP as a leading example). For

Optimal use of tandem biotin and V5 tags in ChIP assays

NARCIS (Netherlands)

K.E. Kolodziej (Katarzyna); F. Pourfarzad, F. (Farzin); E. de Boer (Ernie); S. Krpic (Sanja); F.G. Grosveld (Frank); J. Strouboulis (John)

2009-01-01

textabstractBackground: Chromatin immunoprecipitation (ChIP) assays coupled to genome arrays (Chip-on-chip) or massive parallel sequencing (ChIP-seq) lead to the genome wide identification of binding sites of chromatin associated proteins. However, the highly variable quality of antibodies and the

Improvement of CPU time of Linear Discriminant Function based on MNM criterion by IP

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Shuichi Shinmura

2014-05-01

Full Text Available Revised IP-OLDF (optimal linear discriminant function by integer programming is a linear discriminant function to minimize the number of misclassifications (NM of training samples by integer programming (IP. However, IP requires large computation (CPU time. In this paper, it is proposed how to reduce CPU time by using linear programming (LP. In the first phase, Revised LP-OLDF is applied to all cases, and all cases are categorized into two groups: those that are classified correctly or those that are not classified by support vectors (SVs. In the second phase, Revised IP-OLDF is applied to the misclassified cases by SVs. This method is called Revised IPLP-OLDF.In this research, it is evaluated whether NM of Revised IPLP-OLDF is good estimate of the minimum number of misclassifications (MNM by Revised IP-OLDF. Four kinds of the real data—Iris data, Swiss bank note data, student data, and CPD data—are used as training samples. Four kinds of 20,000 re-sampling cases generated from these data are used as the evaluation samples. There are a total of 149 models of all combinations of independent variables by these data. NMs and CPU times of the 149 models are compared with Revised IPLP-OLDF and Revised IP-OLDF. The following results are obtained: 1 Revised IPLP-OLDF significantly improves CPU time. 2 In the case of training samples, all 149 NMs of Revised IPLP-OLDF are equal to the MNM of Revised IP-OLDF. 3 In the case of evaluation samples, most NMs of Revised IPLP-OLDF are equal to NM of Revised IP-OLDF. 4 Generalization abilities of both discriminant functions are concluded to be high, because the difference between the error rates of training and evaluation samples are almost within 2%.   Therefore, Revised IPLP-OLDF is recommended for the analysis of big data instead of Revised IP-OLDF. Next, Revised IPLP-OLDF is compared with LDF and logistic regression by 100-fold cross validation using 100 re-sampling samples. Means of error rates of

Lessons Learned from resolving massive IPS database change for SPADES+

International Nuclear Information System (INIS)

Kim, Jin-Soo

2016-01-01

Safety Parameter Display and Evaluation System+ (SPADES+) was implemented to meet the requirements for Safety Parameter Display System (SPDS) which are related to TMI Action Plan requirements. SPADES+ monitors continuously the critical safety function during normal, abnormal, and emergency operation mode and generates the alarm output to the alarm server when the tolerance related to safety functions are not satisfied. The alarm algorithm for critical safety function is performed in the NSSS Application Software (NAPS) server of the Information Process System (IPS) and the calculation result will be displayed on the flat panel display (FPD) of the IPS. SPADES+ provides the critical variable to the control room operators to aid them in rapidly and reliable determining the safety status of the plant. Many database point ID names (518 points) were changed. POINT_ID is used in the programming source code, the related documents such as SDS and SRS, and Graphic database. To reduce human errors, computer program and office program’s Macro are used. Though the automatic methods are used for changing POINT_IDs, it takes lots of time to resolve for editing the change list except for making computerized solutions. In IPS, there are many more programs than SPADES+ and over 30,000 POINT_IDs are in IPS database. Changing POINT_IDs could be a burden to software engineers. In case of Ovation system database, there is the Alias field to prevent this kind of problem. The Alias is a kind of secondary key in database

Adjusting the IP $\\beta$ Functions in RHIC

CERN Document Server

Wittmer, W; Pilat, F; Ptitsyn, V; Van Zeijts, J

2004-01-01

The beta functions at the IP can be adjusted without perturbation of other optics functions via several approaches. In this paper we describe a scheme based on a vector knob, which assigns fixed values to the different tuning quadrupoles and scales them by a common multiplier. The values for the knob vector were calculated for a lattice without any errors using MADX. Previous studies for the LHC [1] have shown that this approach can meet the design goals. A specific feature of the RHIC lattice is the nested power supply system. To cope with the resulting problems a detailed response matrix analysis has been carried out and different sets of knobs were calculated and compared. The knobs were tested at RHIC during the 2004 run and preliminary results are discussed. Simultaneously a new approach to measure the beam sizes of both colliding beams at the IP, based on the tunability provided by the knobs, was developed and tested.

Classifier fusion for VoIP attacks classification

Science.gov (United States)

Safarik, Jakub; Rezac, Filip

2017-05-01

SIP is one of the most successful protocols in the field of IP telephony communication. It establishes and manages VoIP calls. As the number of SIP implementation rises, we can expect a higher number of attacks on the communication system in the near future. This work aims at malicious SIP traffic classification. A number of various machine learning algorithms have been developed for attack classification. The paper presents a comparison of current research and the use of classifier fusion method leading to a potential decrease in classification error rate. Use of classifier combination makes a more robust solution without difficulties that may affect single algorithms. Different voting schemes, combination rules, and classifiers are discussed to improve the overall performance. All classifiers have been trained on real malicious traffic. The concept of traffic monitoring depends on the network of honeypot nodes. These honeypots run in several networks spread in different locations. Separation of honeypots allows us to gain an independent and trustworthy attack information.

Host based internet protocol (IP) packet analysis to enhance network security

International Nuclear Information System (INIS)

Ahmad, T.; Ahmad, S.Z.; Yasin, M.M.

2007-01-01

Data communication in a computer network environment is facing serious security threats from numerous sources such as viruses, worms, Zombies etc. These threats can be broadly characterized as internal or external security threats. Internal threats are mainly attributed to sneaker-nets, utility modems and unauthorized users, which can be minimized by skillful network administration, password management and optimum usage policy definition. The external threats need more serious attention as these attacks are mostly coming from public networks such as Internet. Frequency and complexity of such attacks is much higher as compared to internal attacks. This paper presents a host based network layer screening of external and internal IP packets for logging, analyzing and real-time detection of possible IP spoofing and Denial of Service attacks. This work can also be used in tuning security rules definition for gateway firewalls. Software has been developed which intercepts IP traffic and analyses it with respect to integrity and origin of I P packet. The received IP packets are parsed and analyzed for possible signs of intrusion. The results show that by watching and categorizing composition of various transport protocol such as TCP, UDP, ICMP and others along with verifying the origin of received IP packet can help in devising real-time firewall rule and blocking possible external attack. This is highly desirable for fighting against zero day attacks and can result in a better Mean Time between Failures (MTBF) to increase the survivability of computer network. Used in a right context, packet screening and filtering can be a useful tool for provision of reliable and stable network services. (author)

Ataxia-telangiectasia mutated (ATM) deficiency decreases reprogramming efficiency and leads to genomic instability in iPS cells

Energy Technology Data Exchange (ETDEWEB)

Kinoshita, Taisuke [Department of Cell Differentiation, The Sakaguchi Laboratory, School of Medicine, Keio University, Tokyo 160-8582 (Japan); Nagamatsu, Go, E-mail: gonag@sc.itc.keio.ac.jp [Department of Cell Differentiation, The Sakaguchi Laboratory, School of Medicine, Keio University, Tokyo 160-8582 (Japan); Precursory Research for Embryonic Science and Technology, Japan Science and Technology Agency, Kawaguchi, Saitama 332-0012 (Japan); Kosaka, Takeo [Department of Urology, School of Medicine, Keio University, Tokyo 160-8582 (Japan); Takubo, Keiyo [Department of Cell Differentiation, The Sakaguchi Laboratory, School of Medicine, Keio University, Tokyo 160-8582 (Japan); Hotta, Akitsu [Precursory Research for Embryonic Science and Technology, Japan Science and Technology Agency, Kawaguchi, Saitama 332-0012 (Japan); Department of Reprogramming Science, Center for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto (Japan); Ellis, James [Ontario Human iPS Cell Facility, Molecular Genetics, University of Toronto, Developmental and Stem Cell Biology, SickKids, Toronto, Canada MG1L7 (Canada); Suda, Toshio, E-mail: sudato@sc.itc.keio.ac.jp [Department of Cell Differentiation, The Sakaguchi Laboratory, School of Medicine, Keio University, Tokyo 160-8582 (Japan)

2011-04-08

Highlights: {yields} iPS cells were induced with a fluorescence monitoring system. {yields} ATM-deficient tail-tip fibroblasts exhibited quite a low reprogramming efficiency. {yields} iPS cells obtained from ATM-deficient cells had pluripotent cell characteristics. {yields} ATM-deficient iPS cells had abnormal chromosomes, which were accumulated in culture. -- Abstract: During cell division, one of the major features of somatic cell reprogramming by defined factors, cells are potentially exposed to DNA damage. Inactivation of the tumor suppressor gene p53 raised reprogramming efficiency but resulted in an increased number of abnormal chromosomes in established iPS cells. Ataxia-telangiectasia mutated (ATM), which is critical in the cellular response to DNA double-strand breaks, may also play an important role during reprogramming. To clarify the function of ATM in somatic cell reprogramming, we investigated reprogramming in ATM-deficient (ATM-KO) tail-tip fibroblasts (TTFs). Although reprogramming efficiency was greatly reduced in ATM-KO TTFs, ATM-KO iPS cells were successfully generated and showed the same proliferation activity as WT iPS cells. ATM-KO iPS cells had a gene expression profile similar to ES cells and WT iPS cells, and had the capacity to differentiate into all three germ layers. On the other hand, ATM-KO iPS cells accumulated abnormal genome structures upon continuous passages. Even with the abnormal karyotype, ATM-KO iPS cells retained pluripotent cell characteristics for at least 20 passages. These data indicate that ATM does participate in the reprogramming process, although its role is not essential.

Ataxia-telangiectasia mutated (ATM) deficiency decreases reprogramming efficiency and leads to genomic instability in iPS cells

International Nuclear Information System (INIS)

Kinoshita, Taisuke; Nagamatsu, Go; Kosaka, Takeo; Takubo, Keiyo; Hotta, Akitsu; Ellis, James; Suda, Toshio

2011-01-01

Highlights: → iPS cells were induced with a fluorescence monitoring system. → ATM-deficient tail-tip fibroblasts exhibited quite a low reprogramming efficiency. → iPS cells obtained from ATM-deficient cells had pluripotent cell characteristics. → ATM-deficient iPS cells had abnormal chromosomes, which were accumulated in culture. -- Abstract: During cell division, one of the major features of somatic cell reprogramming by defined factors, cells are potentially exposed to DNA damage. Inactivation of the tumor suppressor gene p53 raised reprogramming efficiency but resulted in an increased number of abnormal chromosomes in established iPS cells. Ataxia-telangiectasia mutated (ATM), which is critical in the cellular response to DNA double-strand breaks, may also play an important role during reprogramming. To clarify the function of ATM in somatic cell reprogramming, we investigated reprogramming in ATM-deficient (ATM-KO) tail-tip fibroblasts (TTFs). Although reprogramming efficiency was greatly reduced in ATM-KO TTFs, ATM-KO iPS cells were successfully generated and showed the same proliferation activity as WT iPS cells. ATM-KO iPS cells had a gene expression profile similar to ES cells and WT iPS cells, and had the capacity to differentiate into all three germ layers. On the other hand, ATM-KO iPS cells accumulated abnormal genome structures upon continuous passages. Even with the abnormal karyotype, ATM-KO iPS cells retained pluripotent cell characteristics for at least 20 passages. These data indicate that ATM does participate in the reprogramming process, although its role is not essential.

Nos debemos a la tierra. El Campesino y la creación de una voz para el campo, 1958-1962

Directory of Open Access Journals (Sweden)

Soraya Maite Yie Garzón

2016-01-01

Full Text Available El artículo analiza los lenguajes y contenidos del semanario El Campesino, con el fin de establecer la forma como se materializó el esfuerzo de un sector de la elite política y eclesial del país en el comportamiento político de la población rural colombiana al inicio del Frente Nacional —1958-1962—. Argumentamos que tal esfuerzo implicó: primero, interpelar a diferentes individuos como miembros del “campesinado colombiano”, procurando moldear la voz de este sector como un sujeto político particular; segundo, difundir una narrativa según la cual los distintos sectores de la nación están vinculados entre sí a través de una cadena de deudas morales; y, tercero, hacer de los campesinos objeto de una triple interpelación (como cristianos, ciudadanos colombianos y productores agrícolas.

Periodontal response to all-ceramic crowns (IPS Empress) in general practice.

Science.gov (United States)

Al-Wahadni, A M; Mansour, Y; Khader, Y

2006-02-01

The purpose of this study was to investigate the periodontal response to the presence of all-ceramic crowns (IPS Empress) in general practice patients. The convenience sample included 82 IPS Empress crowns placed in 64 patients. These crowns had been in place for an average of 16.27 (SD 9.26) months and ranged from 6.2 to 48.87 months at the time of clinical examination. Periodontal health status (as determined by dental plaque, gingival health status, periodontal pockets) was assessed around all crowned teeth and around matched contralateral teeth by one calibrated examiner. Periodontal indices utilized included the Plaque Index (PI), Gingival Index (GI) and pocket depth (PD) with calibrated probes graduated in millimetres. Plaque, gingival and PD values for crowned teeth were compared with those for control teeth using Wilcoxon signed-rank test for each clinical parameters. Chi-square was used to test the significance of the difference in their distribution between crowns and control teeth. Statistically, PI (0.35), GI (0.41) and mean PD scores (1.42) of IPS Empress crowned teeth compared less favourably with scores of the control teeth (0.27, 0.23 and 0.86 respectively). Teeth with IPS Empress crowns had poorer periodontal health and more clinically evident plaque than uncrowned teeth.

Combining multiple ChIP-seq peak detection systems using combinatorial fusion.

Science.gov (United States)

Schweikert, Christina; Brown, Stuart; Tang, Zuojian; Smith, Phillip R; Hsu, D Frank

2012-01-01

Due to the recent rapid development in ChIP-seq technologies, which uses high-throughput next-generation DNA sequencing to identify the targets of Chromatin Immunoprecipitation, there is an increasing amount of sequencing data being generated that provides us with greater opportunity to analyze genome-wide protein-DNA interactions. In particular, we are interested in evaluating and enhancing computational and statistical techniques for locating protein binding sites. Many peak detection systems have been developed; in this study, we utilize the following six: CisGenome, MACS, PeakSeq, QuEST, SISSRs, and TRLocator. We define two methods to merge and rescore the regions of two peak detection systems and analyze the performance based on average precision and coverage of transcription start sites. The results indicate that ChIP-seq peak detection can be improved by fusion using score or rank combination. Our method of combination and fusion analysis would provide a means for generic assessment of available technologies and systems and assist researchers in choosing an appropriate system (or fusion method) for analyzing ChIP-seq data. This analysis offers an alternate approach for increasing true positive rates, while decreasing false positive rates and hence improving the ChIP-seq peak identification process.

The effect of zirconia on flexural strength of IPS Empress 2 ceramic

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Kermanshah H

2007-06-01

Full Text Available Background and Aim: All ceramic, inlay-retained resin bonded fixed partial denture is a conservative method for replacement of missing teeth, because of minimal tooth reduction. The connector between the retainer and the pontic is the weak point of these bridges. Reinforcement of ceramic core will increase the clinical longevity. The aim of this study was to determine the effect of zirconia on flexural strength of IPS Empress 2 core ceramic.Materials and Methods: In this experimental in vitro study, twenty eight bar shape specimens (17´3.1´3.1 mm were made of four different materials: (1 Slip casting in-ceram alumina core (control group (2 Hot-pressed lithium disilicate core ceramic (IPS Empress 2 (3 IPS Empress 2 with cosmopost (zirconia post inserted longitudinally in the center of the bar (4 IPS Empress 2 with cosmopost (zirconia post inserted longitudinally in bottom of the bar. Specimens were subjected to three-point flexure loading with the span of 15mm, at a cross-head speed of 0.5 mm/min. Failure loads were recorded and analyzed using one-way ANOVA and Tomhane Post-hoc tests and p<0.05 was set as the level of significance. Fractured surfaces were then observed by scanning electron microscope (SEM. Four additional samples were made as the third group, and zirconia-IPS interface was observed by SEM before fracture.Results: Mean values and standard deviations of three point flexural strengths of groups 1 to 4, were: 378.4±44.6, 258.6±27.5, 144.3±51.7, 230±22.3 MPa respectively. All the groups were statistically different from each other (P<0.05, except groups 2 and 4. The flexural strengths of groups 2, 3, 4 were significantly lower than group 1. Group 3 had the lowest flexural strength. SEM analysis showed that the initiated cracks propagated in the interface of zirconia post and IPS Empress 2 ceramic.Conclusion: Based on the results of this study, inserting zirconia post (cosmopost in IPS Empress 2 ceramic does not reinforce all

Evolution of the PI - Productivity Index; Evolucao do IP - Indice de Produtividade

Energy Technology Data Exchange (ETDEWEB)

Feitosa, Gilvan Soares [Petroleo Brasileiro S.A. (PETROBRAS), Rio de Janeiro, RJ (Brazil)

2012-07-01

The productivity index (PI), the most direct and widely used measure of a well productivity, is defined as the ratio of oil-well rate to the associated pressure drawdown - from average reservoir pressure to bottom hole-flowing-well pressure. It is known that the actual value of PI can only be attained at pseudosteady-state condition, which requires a lot of time (days, or even months), what is not practical for most well tests. For this reason, PI is often obtained from short transient flow test, which gives usually an overestimate of the actual PI. How larger than the actual value is the transient PI? This paper investigates the PI evolution, from the earlier transient well's production period up to the pseudosteady-state flow establishment, under single-phase flow, and later on, as pressure drops below saturation pressure and then oil and gas flow through the reservoir to the well. For analysis of PI during the transient period is defined a dimensionless PI (IP{sub D}), as the ratio of the time-dependent transient PI (IP{sub t}), to the constant pseudosteady-state PI (IP{sub pss}). For transient radial flow, IP{sub D} is developed as a function of dimensionless time, t{sub DA}, and depends on the stabilized drainage area, the Dietz shape factor, the skin factor and the well radius. It is shown that transient PI (IP{sub t}) is always greater than the actual PI (IP{sub pss}) and decreases monotonically with time. At the infinite-acting end IPt reaches the smallest value, which is the closest to the actual pseudosteady-state PI, in the range of 1 to 60% higher, for a broad range of shape factors. The more eccentric the well in the drainage area the more IP{sub t} departs from the actual PI. It is presented a couple of reservoir-limit well test field-cases, where the well was produced long enough until a pseudosteady-state flow was established. Its results, among others, illustrate and substantiate the main theoretical developments of this work. (author)

Capturing value from IP in a global environment

DEFF Research Database (Denmark)

Alcacer, Juan; Beukel, Karin; Cassiman, Bruno

section. Global companies will need to organize cross-functional value capture teams focused on appropriating value from their know-how and reputation by combining different institutional, market, and non-market tools, depending on the institutional and business environment in a particular region.......This paper documents the strong growth in tools used by firms to protect their intellectual property (IP), develop their know-how, and build and maintain their reputation globally. We focus on three tools that have become increasingly important in the last several decades: patents, trademarks...... experiencing the most growth. These trends in applications are less evident when we study which applications are actually granted. For example, the shift in IP activity toward middle-income countries and Asia is less pronounced, and the most developed countries still lead globally. Moreover, there seems...

Analyzátor kvality hovorů VoIP

OpenAIRE

Basel, Martin

2014-01-01

Tato bakalářská práce se zabývá metodami pro hodnocení kvality hovorů VoIP. Je zde vysvětlen rozbor protokolu RTP/RTCP a následné počítání statistik potřebných pro určení kvality hovorů. V této práci je také popsána metoda, která byla implementována do pluginů pro sondu FlowMon. Budete zde seznámeni s výsledky a s porovnáním s ostatními programy. This bachelor's thesis focuses on methods for evaluating quality of VoIP calls. You can read about analysis of RTP/RTCP packets and use this know...

Predictive IP controller for robust position control of linear servo system.

Science.gov (United States)

Lu, Shaowu; Zhou, Fengxing; Ma, Yajie; Tang, Xiaoqi

2016-07-01

Position control is a typical application of linear servo system. In this paper, to reduce the system overshoot, an integral plus proportional (IP) controller is used in the position control implementation. To further improve the control performance, a gain-tuning IP controller based on a generalized predictive control (GPC) law is proposed. Firstly, to represent the dynamics of the position loop, a second-order linear model is used and its model parameters are estimated on-line by using a recursive least squares method. Secondly, based on the GPC law, an optimal control sequence is obtained by using receding horizon, then directly supplies the IP controller with the corresponding control parameters in the real operations. Finally, simulation and experimental results are presented to show the efficiency of proposed scheme. Copyright © 2016 ISA. Published by Elsevier Ltd. All rights reserved.

HPeak: an HMM-based algorithm for defining read-enriched regions in ChIP-Seq data

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Maher Christopher A

2010-07-01

Full Text Available Abstract Background Protein-DNA interaction constitutes a basic mechanism for the genetic regulation of target gene expression. Deciphering this mechanism has been a daunting task due to the difficulty in characterizing protein-bound DNA on a large scale. A powerful technique has recently emerged that couples chromatin immunoprecipitation (ChIP with next-generation sequencing, (ChIP-Seq. This technique provides a direct survey of the cistrom of transcription factors and other chromatin-associated proteins. In order to realize the full potential of this technique, increasingly sophisticated statistical algorithms have been developed to analyze the massive amount of data generated by this method. Results Here we introduce HPeak, a Hidden Markov model (HMM-based Peak-finding algorithm for analyzing ChIP-Seq data to identify protein-interacting genomic regions. In contrast to the majority of available ChIP-Seq analysis software packages, HPeak is a model-based approach allowing for rigorous statistical inference. This approach enables HPeak to accurately infer genomic regions enriched with sequence reads by assuming realistic probability distributions, in conjunction with a novel weighting scheme on the sequencing read coverage. Conclusions Using biologically relevant data collections, we found that HPeak showed a higher prevalence of the expected transcription factor binding motifs in ChIP-enriched sequences relative to the control sequences when compared to other currently available ChIP-Seq analysis approaches. Additionally, in comparison to the ChIP-chip assay, ChIP-Seq provides higher resolution along with improved sensitivity and specificity of binding site detection. Additional file and the HPeak program are freely available at http://www.sph.umich.edu/csg/qin/HPeak.

A comparison of interferon-γ and IP-10 for the diagnosis of tuberculosis

DEFF Research Database (Denmark)

Holm, Line Lindebo; Rose, Michala Vaaben; Kimaro, Godfather

2014-01-01

OBJECTIVE: Interferon-γ and IP-10 release assays are diagnostic tests for tuberculosis infection. We have compared the accuracy of IP-10 and QuantiFERON-TB Gold In-tube [QFT-IT] in Tanzanian children suspected of having active tuberculosis (TB). METHODS: Hospitalized Tanzanian children...

Accounting for immunoprecipitation efficiencies in the statistical analysis of ChIP-seq data

NARCIS (Netherlands)

Bao, Yanchun; Vinciotti, Veronica; Wit, Ernst; 't Hoen, Peter A C

2013-01-01

Background: ImmunoPrecipitation (IP) efficiencies may vary largely between different antibodies and between repeated experiments with the same antibody. These differences have a large impact on the quality of ChIP-seq data: a more efficient experiment will necessarily lead to a higher signal to

Unusual Father-to-Daughter Transmission of Incontinentia Pigmenti Due to Mosaicism in IP Males.

Science.gov (United States)

Fusco, Francesca; Conte, Matilde Immacolata; Diociaiuti, Andrea; Bigoni, Stefania; Branda, Maria Francesca; Ferlini, Alessandra; El Hachem, Maya; Ursini, Matilde Valeria

2017-09-01

Incontinentia pigmenti (IP; Online Mendelian Inheritance in Man catalog #308300) is an X-linked dominant ectodermal disorder caused by mutations of the inhibitor of κ polypeptide gene enchancer in B cells, kinase γ ( IKBKG )/ nuclear factor κB, essential modulator ( NEMO ) gene. Hemizygous IKBKG/NEMO loss-of-function (LoF) mutations are lethal in males, thus patients are female, and the disease is always transmitted from an IP-affected mother to her daughter. We present 2 families with father-to-daughter transmission of IP and provide for the first time molecular evidence that the combination of somatic and germ-line mosaicism for IKBKG/NEMO loss of function mutations in IP males resulted in the transmission of the disease to a female child. We searched for the IKBKG/NEMO mutant allele in blood, urine, skin, and sperm DNA and found that the 2 fathers were somatic and germ-line mosaics for the p.Gln132×mutation or the exon 4-10 deletion of IKBKG/NEMO , respectively. The highest level of IKBKG/NEMO mutant cells was detected in the sperm, which might explain the recurrence of the disease. We therefore recommend careful clinical evaluation in IP male cases and the genetic investigation in sperm DNA to ensure correct genetic counseling and prevent the risk of paternal transmission of IP. Copyright © 2017 by the American Academy of Pediatrics.

Teaching Network Security with IP Darkspace Data

Science.gov (United States)

Zseby, Tanja; Iglesias Vázquez, Félix; King, Alistair; Claffy, K. C.

2016-01-01

This paper presents a network security laboratory project for teaching network traffic anomaly detection methods to electrical engineering students. The project design follows a research-oriented teaching principle, enabling students to make their own discoveries in real network traffic, using data captured from a large IP darkspace monitor…

High throughput mutagenesis for identification of residues regulating human prostacyclin (hIP) receptor expression and function.

Science.gov (United States)

Bill, Anke; Rosethorne, Elizabeth M; Kent, Toby C; Fawcett, Lindsay; Burchell, Lynn; van Diepen, Michiel T; Marelli, Anthony; Batalov, Sergey; Miraglia, Loren; Orth, Anthony P; Renaud, Nicole A; Charlton, Steven J; Gosling, Martin; Gaither, L Alex; Groot-Kormelink, Paul J

2014-01-01

The human prostacyclin receptor (hIP receptor) is a seven-transmembrane G protein-coupled receptor (GPCR) that plays a critical role in vascular smooth muscle relaxation and platelet aggregation. hIP receptor dysfunction has been implicated in numerous cardiovascular abnormalities, including myocardial infarction, hypertension, thrombosis and atherosclerosis. Genomic sequencing has discovered several genetic variations in the PTGIR gene coding for hIP receptor, however, its structure-function relationship has not been sufficiently explored. Here we set out to investigate the applicability of high throughput random mutagenesis to study the structure-function relationship of hIP receptor. While chemical mutagenesis was not suitable to generate a mutagenesis library with sufficient coverage, our data demonstrate error-prone PCR (epPCR) mediated mutagenesis as a valuable method for the unbiased screening of residues regulating hIP receptor function and expression. Here we describe the generation and functional characterization of an epPCR derived mutagenesis library compromising >4000 mutants of the hIP receptor. We introduce next generation sequencing as a useful tool to validate the quality of mutagenesis libraries by providing information about the coverage, mutation rate and mutational bias. We identified 18 mutants of the hIP receptor that were expressed at the cell surface, but demonstrated impaired receptor function. A total of 38 non-synonymous mutations were identified within the coding region of the hIP receptor, mapping to 36 distinct residues, including several mutations previously reported to affect the signaling of the hIP receptor. Thus, our data demonstrates epPCR mediated random mutagenesis as a valuable and practical method to study the structure-function relationship of GPCRs.

High throughput mutagenesis for identification of residues regulating human prostacyclin (hIP receptor expression and function.

Directory of Open Access Journals (Sweden)

Anke Bill

Full Text Available The human prostacyclin receptor (hIP receptor is a seven-transmembrane G protein-coupled receptor (GPCR that plays a critical role in vascular smooth muscle relaxation and platelet aggregation. hIP receptor dysfunction has been implicated in numerous cardiovascular abnormalities, including myocardial infarction, hypertension, thrombosis and atherosclerosis. Genomic sequencing has discovered several genetic variations in the PTGIR gene coding for hIP receptor, however, its structure-function relationship has not been sufficiently explored. Here we set out to investigate the applicability of high throughput random mutagenesis to study the structure-function relationship of hIP receptor. While chemical mutagenesis was not suitable to generate a mutagenesis library with sufficient coverage, our data demonstrate error-prone PCR (epPCR mediated mutagenesis as a valuable method for the unbiased screening of residues regulating hIP receptor function and expression. Here we describe the generation and functional characterization of an epPCR derived mutagenesis library compromising >4000 mutants of the hIP receptor. We introduce next generation sequencing as a useful tool to validate the quality of mutagenesis libraries by providing information about the coverage, mutation rate and mutational bias. We identified 18 mutants of the hIP receptor that were expressed at the cell surface, but demonstrated impaired receptor function. A total of 38 non-synonymous mutations were identified within the coding region of the hIP receptor, mapping to 36 distinct residues, including several mutations previously reported to affect the signaling of the hIP receptor. Thus, our data demonstrates epPCR mediated random mutagenesis as a valuable and practical method to study the structure-function relationship of GPCRs.

Drogadição e atos infracionais na voz do adolescente em conflito com a lei

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Sandra Eni Fernandes Nunes Pereira

Full Text Available Por meio das abordagens sistêmica e psicossocial, o presente estudo tem como objetivo descrever e discutir a relação entre os níveis de dependência relacional das drogas e a prática de atos infracionais entre os jovens, na perspectiva do adolescente em conflito com a lei. As informações foram coletadas por entrevistas semi-estruturadas, aplicadas em 29 adolescentes, autores de infração, da Vara da Infância e Juventude de Brasília. O método de análise refere-se à análise de conteúdo do tipo construtivo-interpretativo. Os resultados apontam várias conexões entre os níveis de dependência relacional das drogas (efeitos, crenças, relações afetivas, pares, provedores, fornecedores e a prática de infrações. Os diferentes níveis de dependência identificados na voz dos adolescentes mostram a multiplicidade e complexidade das relações entre a drogadição e a prática de atos infracionais entre jovens e, portanto, a necessidade de um trabalho de intervenção em rede.

Doenças das crianças goianas no século XIX. Os registros de óbitos do Hospital de Caridade São Pedro de Alcântara

OpenAIRE

Sônia Maria de Magalhães; Elias Nazareno

2013-01-01

Recuperar a história da infância no Brasil constitui-se numa tarefa árdua empreendida pelos historiadores desde as últimas décadas do século XX. As pesquisas desenvolvidas buscam dar voz aos meninos e meninas por intermédio da pesquisa e da revalorização do documento histórico. Apesar dos grandes avanços, pouco se conhece sobre os jogos e brincadeiras, a literatura infantil, a saúde e a educação. Deste modo, este estudo propende a municiar subsídios sobre as doenças e a alimentação das crianç...

A simple method to quantitate IP-10 in dried blood and plasma spots

DEFF Research Database (Denmark)

Aabye, Martine G; Eugen-Olsen, Jesper; Werlinrud, Anne Marie

2012-01-01

Antigen specific release of IP-10 is an established marker for infection with M.tuberculosis. Compared to IFN-γ, IP-10 is released in 100-fold higher concentrations enabling the development of novel assays for detection. Dried blood spots are a convenient sample for high throughput newborn...

Joint modeling of ChIP-seq data via a Markov random field model

NARCIS (Netherlands)

Bao, Yanchun; Vinciotti, Veronica; Wit, Ernst; 't Hoen, Peter A C

Chromatin ImmunoPrecipitation-sequencing (ChIP-seq) experiments have now become routine in biology for the detection of protein-binding sites. In this paper, we present a Markov random field model for the joint analysis of multiple ChIP-seq experiments. The proposed model naturally accounts for

Security Analysis System to Detect Threats on a SIP VoIP Infrasctructure Elements

Directory of Open Access Journals (Sweden)

Filip Rezac

2011-01-01

Full Text Available SIP PBX is definitely the alpha and omega of any IP telephony infrastructure and frequently also provides other services than those related to VoIP traffic. These exchanges are, however, very often the target of attacks by external actors. The article describes a system that was developed on VSB-TU Ostrava as a testing tool to verify if the target VoIP PBX is adequately secured and protected against any real threats. The system tests the SIP element for several usually occurring attacks and it compiles evaluation of its overall security on the basis of successfully or unsuccessfully penetrations. The article describes the applications and algorithms that are used by system and the conclusion consists recommendations and guidelines to ensure effective protection against VoIP PBX threats. The system is designed as an open-source web application, thus allowing independent access and is fully extensible to other test modules.

Pulse to pulse beam trajectory determination at the IP

International Nuclear Information System (INIS)

Koska, W.; Wagner, S.

1988-01-01

It has long been known that a precise measurement of the SLC beam trajectory through the IP region is vital both from a machine and a detector point of view. One of the primary techniques used to maximize luminosity is the measurement of the deflection angle of one beam produced by the electromagnetic interaction with the other beam. In order to implement this procedure a pair of precision Beam Position Monitors (BPMs) were installed within the Final Triplet of quadrapoles on each side of the IP. Before the IP BPMs could be used to measure beam-beam deflection, a series of measurements were made of the coefficients which relate the setting of an orbit correction magnet to the position of the beam at a particular BPM (R 12 s). The purpose was to expose any problems such as misconnected cables, etc., by comparing the measured R 12 s with theoretical predictions from the model of the Final Focus region. A technique developed that uses position measurements in the long BPMs to determine a three parameter fit to the beam trajectory at the IP. The three parameters in the fit are the beam position, the incoming angle and the deflection angle. The result was very successful and allows the observation of beam-beam deflection even under marginal conditions. The purpose of this memo is to clear up the technical points and to demonstrate that the simplicity of the fit should allow the implementation of this procedure at the micro level, where it could provide trajectory information in real time which would go a long way toward making it useful as a fast feedback tool and in addition allow easy real time access to beam position data by the Mark II

Validation of DAB2IP methylation and its relative significance in predicting outcome in renal cell carcinoma

Science.gov (United States)

Zhao, Liang-Yun; Kapur, Payal; Wu, Kai-Jie; Wang, Bin; Yu, Yan-Hong; Liao, Bing; He, Da-Lin; Chen, Wei; Margulis, Vitaly; Hsieh, Jer-Tsong; Luo, Jun-Hang

2016-01-01

We have recently reported tumor suppressive role of DAB2IP in RCC development. In this study, We identified one CpG methylation biomarker (DAB2IP CpG1) located UTSS of DAB2IP that was associated with poor overall survival in a cohort of 318 ccRCC patients from the Cancer Genome Atlas (TCGA). We further validated the prognostic accuracy of DAB2IP CpG methylation by pyrosequencing quantitative methylation assay in 224 ccRCC patients from multiple Chinese centers (MCHC set), and 239 patients from University of Texas Southwestern Medical Center at Dallas (UTSW set) by using FFPE samples. DAB2IP CpG1 can predict the overall survival of patients in TCGA, MCHC, and UTSW sets independent of patient age, Fuhrman grade and TNM stage (all p<0.05). DAB2IP CpG1 successfully categorized patients into high-risk and low-risk groups with significant differences of clinical outcome in respective clinical subsets, regardless of age, sex, grade, stage, or race (HR: 1.63-7.83; all p<0.05). The detection of DAB2IP CpG1 methylation was minimally affected by ITH in ccRCC. DAB2IP mRNA expression was regulated by DNA methylation in vitro. DAB2IP CpG1 methylation is a practical and repeatable biomarker for ccRCC, which can provide prognostic value that complements the current staging system. PMID:27129174

Poema sujo: dois tempos, dois sujeitos num corpo lírico = Dirty poem: two times, two subjects in a lyrical body

Directory of Open Access Journals (Sweden)

Assis, Maria do Socorro Pereira de

2011-01-01

Full Text Available O Poema sujo, de Ferreira Gullar, é o corpo lírico sobre o qual especulamos a existência da voz de um sujeito histórico transubstanciada numa linguagem que acolhe o passado e o presente no mesmo instante. Essa voz possui a aparência do real, sem sê-lo; nela há signos que atestam o objeto temporal situado, ao mesmo tempo em que o fazem eterno. No encontro do regime estético da arte proposto por Jacques Ranciére, com a ideia de memória engajada – síntese teórica de proposições de Jean Paul Sartre e Paul Ricoeur – discutimos o duplo caráter desse poema que tem sido visto apenas como memorialístico, afirmando o dasein de uma poética de amalgamento de pensamento e linguagem

Global IP6K1 deletion enhances temperature modulated energy expenditure which reduces carbohydrate and fat induced weight gain

Directory of Open Access Journals (Sweden)

Qingzhang Zhu

2017-01-01

Full Text Available Objective: IP6 kinases (IP6Ks regulate cell metabolism and survival. Mice with global (IP6K1-KO or adipocyte-specific (AdKO deletion of IP6K1 are protected from diet induced obesity (DIO at ambient (23 °C temperature. AdKO mice are lean primarily due to increased AMPK mediated thermogenic energy expenditure (EE. Thus, at thermoneutral (30 °C temperature, high fat diet (HFD-fed AdKO mice expend energy and gain body weight, similar to control mice. IP6K1 is ubiquitously expressed; thus, it is critical to determine to what extent the lean phenotype of global IP6K1-KO mice depends on environmental temperature. Furthermore, it is not known whether IP6K1 regulates AMPK mediated EE in cells, which do not express UCP1. Methods: Q-NMR, GTT, food intake, EE, QRT-PCR, histology, mitochondrial oxygen consumption rate (OCR, fatty acid metabolism assays, and immunoblot studies were conducted in IP6K1-KO and WT mice or cells. Results: Global IP6K1 deletion mediated enhancement in EE is impaired albeit not abolished at 30 °C. As a result, IP6K1-KO mice are protected from DIO, insulin resistance, and fatty liver even at 30 °C. Like AdKO, IP6K1-KO mice display enhanced adipose tissue browning. However, unlike AdKO mice, thermoneutrality only partly abolishes browning in IP6K1-KO mice. Cold (5 °C exposure enhances carbohydrate expenditure, whereas 23 °C and 30 °C promote fat oxidation in HFD-KO mice. Furthermore, IP6K1 deletion diminishes cellular fat accumulation via activation of the AMPK signaling pathway. Conclusions: Global deletion of IP6K1 ameliorates obesity and insulin resistance irrespective of the environmental temperature conditions, which strengthens its validity as an anti-obesity target. Keywords: IP6K, Obesity, Diabetes, Energy expenditure, β-oxidation