WorldWideScience

Sample records for voluntary fertility regulation

  1. Regulating bodily integrity: cosmetic surgery and voluntary limb amputation.

    Science.gov (United States)

    Kennedy, Aileen

    2012-12-01

    Cosmetic surgery and voluntary limb amputation share a number of features. Both procedures are patient-driven forms of body shaping that can only be performed by surgeons, and therefore the procedures require the imprimatur of the medical profession to be lawful. Both invoke identity construction as a central legitimating factor that renders the procedures therapeutic. The legal regulation of surgery is subsumed within general principles regulating medical practice, where autonomy and consent are constituted as fundamental authorising principles. The legitimacy of consent to surgical intervention operates unevenly in relation to these two forms of surgery. Amputation of healthy limbs is presumed to be non-therapeutic. Capacity is closely interrogated and minutely scrutinised. Consent to cosmetic surgery, by contrast, is presumed to be a valid expression of autonomy and self-determination.

  2. Benefits of voluntary industry standards: The triumph of experience over regulation

    Energy Technology Data Exchange (ETDEWEB)

    O`Leary, J.T. [National Mining Association, Washington, DC (United States)

    1996-12-31

    Voluntary international standards for mining machinery may gradually replace many national regulations. The days of establishing voluntary standards nation by nation, inhibiting the important flow of international trade, could be numbered. This does not mean that nations will cease domestic regulatory activities within their boundaries, but rulemaking will pay considerable attention to voluntary international standards and will likely strive for compatibility with voluntary international standards. International standards setting bodies are developing standards for machine safety. When these standards are complete and adopted, some nations will require machinery to comport with them. International commerce in products that do not conform to these voluntary international standards may be discouraged.

  3. Suprachiasmatic vasopressin and the circadian regulation of voluntary locomotor behavior.

    Science.gov (United States)

    Cormier, Holly C; Della-Maggiore, Valeria; Karatsoreos, Ilia N; Koletar, Margaret M; Ralph, Martin R

    2015-01-01

    A role for arginine vasopressin in the circadian regulation of voluntary locomotor behavior (wheel running activity) was investigated in the golden hamster, Mesocricetus auratus. Spontaneous nocturnal running was suppressed in a dose-dependent manner by systemic injections of vasopressin, and also in a concentration-dependent manner by microinjections directly into the hypothalamic suprachiasmatic nucleus. Pre-injections of a vasopressin V1 receptor antagonist into the nucleus reduced the suppression of behavior by vasopressin. Ethogram analyses revealed that peripheral drug injections predominantly increased grooming, flank marking, and sleep-related behaviors. Central injections did not induce sleep, but increased grooming and periods of 'quiet vigilance' (awake but not moving). Nocturnal behavioral profiles following either peripheral or central injections were similar to those shown by untreated animals in the hour prior to the onset of nocturnal wheel running. Site control vasopressin injections into the medial preoptic area or periaqueductal gray increased flank marking and grooming, but had no significant effect on locomotion, suggesting behavioral specificity of a vasopressin target near the suprachiasmatic nucleus. Both peripheral and central administration increased FOS-like immunoreactivity in the retinorecipient core of the suprachiasmatic nucleus. The distribution of FOS-positive cells overlapped the calbindin subregion, but was more extensive, and most calbindin-positive cells did not co-express FOS. We propose a model of temporal behavioral regulation wherein voluntary behavior, such as nocturnal locomotor activity, is inhibited by the activity of neurons in the suprachiasmatic ventrolateral core that project to the posterior hypothalamus and are driven by rhythmic vasopressin input from the dorsomedial shell.

  4. Regulation of animal experimentation: Canada's program of voluntary control.

    Science.gov (United States)

    Rowsell, H C

    1986-01-01

    The Canadian Council on Animal Care (CCAC), is an autonomous advisory and supervisory body responsible for surveillance of experimental animal care and use in Canada's universities, government laboratories and pharmaceutical houses. Its 20-organization membership includes representatives of government, industry, academia and the humane movement. CCAC's voluntary peer review program depends heavily on institutional animal care committees who evaluate the ethical aspects of animal study protocols, and provide day-to-day surveillance of animal care. Its scientific teams, each of which also includes an appointee of the Canadian Federation of Humane Societies (CFHS), conduct assessments based on CCAC's "Guide to the Care and Use of Experimental Animals" (Volume 1, 1980; Volume 2, 1984). Canada's two major funding agencies, the Medical Research Council (MRC) and the Natural Sciences and Engineering Research Council (NSERC), have recently stated that, in the event of an institution's continued non-compliance with CCAC requirements, sanctions may include the "freezing or withdrawal of any or all research programs funded by either or both Research Councils in an institution". This presentation describes the CCAC program of voluntary peer review and examines historic aspects of animal issues in Canada, from that country's early reliance on the fur trade, to today's almost defunct harp seal fishery, from Banting and Best's discovery of insulin, to development of the pacemaker.

  5. Some cultural factors affecting costs of fertility regulation.

    Science.gov (United States)

    Nag, M

    1984-01-01

    This paper presents a framework of the costs or constraints in the use of fertility regulation, reviews the existing knowledge on the subject in a cross-cultural context, and indicates the need for further studies. It is suggested that the apparent contradiction noted in fertility surveys between a couple's desire to have no more children or to postpone the next birth and actual behavior can be explained by the costs involved in the use of fertility regulation methods. The costs of fertility regulation can be broadly classified into 4 categories: 1) physical/health (disruption of menstrual cycle, side effects and health hazards of contraceptive methods, perceived health hazards based on ethno-physical concepts, and sacrifice of sexual pleasure); 2) psychic (violation of sexual modesty and human dignity, conflict with religious beliefs; 3) social opinion (challenges to spouse and sex role expectations, challenges to social influence group); and 4) economic (money, time). The economic costs of fertility regulation to individuals vary greatly according to the presence or absence of public sector family planning programs. A substantial part of these costs could be eliminated by national and international programs. So far, no study has focused on the costs of fertility regulation and factors affecting them. A methodology that combines elements of both a questionnaire survey and anthropological investigation and collects data on both the individual and community levels may be most amenable to assessing the impact of costs on the use or nonuse of fertility regulation.

  6. Neural Networks Involved in Voluntary and Involuntary Vocal Pitch Regulation in Experienced Singers

    Science.gov (United States)

    Zarate, Jean Mary; Wood, Sean; Zatorre, Robert J.

    2010-01-01

    In an fMRI experiment, we tested experienced singers with singing tasks to investigate neural correlates of voluntary and involuntary vocal pitch regulation. We shifted the pitch of auditory feedback (plus or minus 25 or 200 cents), and singers either: (1) ignored the shift and maintained their vocal pitch or (2) changed their vocal pitch to…

  7. Voluntary emotion regulation in anorexia nervosa: A preliminary emotion-modulated startle investigation.

    Science.gov (United States)

    Racine, Sarah E; Forbush, Kelsie T; Wildes, Jennifer E; Hagan, Kelsey E; Pollack, Lauren O; May, Casey

    2016-06-01

    Emotion regulation difficulties are implicated in the development and maintenance of anorexia nervosa (AN). However, research has been limited by an almost exclusive reliance on self-report. This study is the first to use the emotion-modulated startle paradigm (EMSP) to investigate emotional reactivity and voluntary emotion regulation in individuals with AN. Twenty women with AN viewed negative, positive, neutral, and food images and were asked to enhance, suppress, or maintain their emotional responses mid-way through picture presentation. Startle eyeblink magnitudes in response to startle probes administered prior, and subsequent, to regulation instructions indexed emotional reactivity and regulation, respectively. On emotional reactivity trials, startle magnitudes were greater for negative, positive, and food images, compared to neutral images. Participants had difficulty suppressing startle responses to negative and food images, as indicated by non-significant suppress-maintain comparisons. In contrast, startle responses to enhance and suppress cues during presentation of pleasant images were comparable and significantly lower than maintain cues. Findings converge with self-report data to suggest that patients with AN have difficulties with voluntary emotion regulation. The EMSP may be a promising trans-diagnostic method for examining emotion regulation difficulties that underlie risk for eating disorders and other psychiatric conditions.

  8. Regulation of male fertility by X-linked genes.

    Science.gov (United States)

    Zheng, Ke; Yang, Fang; Wang, Peijing Jeremy

    2010-01-01

    Infertility is a worldwide reproductive health problem, affecting men and women about equally. Mouse genetic studies demonstrate that more than 200 genes specifically or predominantly regulate fertility. However, few genetic causes of infertility in humans have been identified. Here, we focus on the regulation of male fertility by X-linked, germ cell-specific genes. Previous genomic studies reveal that the mammalian X chromosome is enriched for genes expressed in early spermatogenesis. Recent genetic studies in mice show that X-linked, germ cell-specific genes, such as A-kinase anchor protein 4 (Akap4), nuclear RNA export factor 2 (Nxf2), TBP-associated factor 7l (Taf7l), and testis-expressed gene 11 (Tex11), indeed play important roles in the regulation of male fertility. Moreover, we find that the Taf7l Tex11 double-mutant males exhibit much more severe defects in meiosis than either single mutant, suggesting that these 2 X-linked genes regulate male meiosis synergistically. The X-linked, germ cell-specific genes are particularly attractive in the study of male infertility in humans. Because males are hemizygous for X-linked genes, loss-of-function mutations in the single-copy X-linked genes, unlike in autosomal genes, would not be masked by a normal allele. The genetic studies of X-linked, germ cell-specific genes in mice have laid a foundation for mutational analysis of their human orthologues in infertile men.

  9. Immunization to regulate fertility: biological and cultural frameworks.

    Science.gov (United States)

    Schrater, A F

    1995-09-01

    Deliberate immunization to control fertility differs from that to control disease. Those differences can be discussed within various frameworks, e.g., intent, recipient population, biological bases, and immunological targets. Others include differing perspectives of developers, providers and users, and rights of the state to impose programs of control. Almost all of the differences are grounded in the social, economic, and gendered aspects of societies. The intent of providing a fertility-regulating vaccine is to prevent pregnancy. In theory, men as well as women could receive such vaccines; in reality, most are designed for women. Traditional vaccines are intended to prevent disease and are generally given to susceptible individuals whether male or female, child or adult. The biological bases of contraceptive vaccines are molecules specific to reproduction. The immune response generated by most anti-fertility vaccines is directed toward 'self', one's own cells and molecules. In contrast, the bases of traditional vaccines are materials derived from non-self, disease-causing microorganisms; the immunological targets are those microorganisms or their toxic products. From a developer perspective vaccines that regulate fertility differ little from those that control disease; both prevent a particular condition. Developers cite these advantages to contraceptive vaccines: non-invasive, no serious side-effects, easy to use, reduced patient failure, and long-lasting but naturally reversible. Because anti-fertility vaccines have been tested only in small-scale clinical trials, information on user reactions and experiences is limited. Not surprisingly, the perspectives of women's health advocates and of potential users (mostly women) often differ markedly from those of developers. Women cite as disadvantages the cryptic nature of immunity which leaves one without an obvious signal for the beginning of protection (against pregnancy) and its decline, and the inability to 'turn

  10. Voluntary Environmental Governance Arrangements

    NARCIS (Netherlands)

    van der Heijden, J.

    2012-01-01

    Voluntary environmental governance arrangements have focal attention in studies on environmental policy, regulation and governance. The four major debates in the contemporary literature on voluntary environmental governance arrangements are studied. The literature falls short of sufficiently

  11. Voluntary Environmental Governance Arrangements

    NARCIS (Netherlands)

    van der Heijden, J.

    2012-01-01

    Voluntary environmental governance arrangements have focal attention in studies on environmental policy, regulation and governance. The four major debates in the contemporary literature on voluntary environmental governance arrangements are studied. The literature falls short of sufficiently specify

  12. Monsoon oscillations regulate fertility of the Red Sea

    KAUST Repository

    Raitsos, Dionysios E.

    2015-02-16

    Tropical ocean ecosystems are predicted to become warmer, more saline, and less fertile in a future Earth. The Red Sea, one of the warmest and most saline environments in the world, may afford insights into the function of the tropical ocean ecosystem in a changing planet. We show that the concentration of chlorophyll and the duration of the phytoplankton growing season in the Red Sea are controlled by the strength of the winter Arabian monsoon (through horizontal advection of fertile waters from the Indian Ocean). Furthermore, and contrary to expectation, in the last decade (1998-2010) the winter Red Sea phytoplankton biomass has increased by 75% during prolonged positive phases of the Multivariate El Niño-Southern Oscillation Index. A new mechanism is reported, revealing the synergy of monsoon and climate in regulating Red Sea greenness. © 2015 The Authors.

  13. Centrifugal regulation of task-relevant somatosensory signals to trigger a voluntary movement.

    Science.gov (United States)

    Kida, Tetsuo; Wasaka, Toshiaki; Nakata, Hiroki; Kakigi, Ryusuke

    2006-03-01

    Many previous papers have reported the modulation of somatosensory evoked potentials (SEPs) during voluntary movement, but the locus and mechanism underlying the movement-induced centrifugal modulation of the SEPs elicited by a task-relevant somatosensory stimulus still remain unclear. We investigated the centrifugal modulation of the SEPs elicited by a task-relevant somatosensory stimulus which triggers a voluntary movement in a forewarned reaction time task. A pair of warning (S1: auditory) and imperative stimuli (S2: somatosensory) was presented with a 1 s interstimulus interval. Subjects were instructed to respond by moving the hand ipsilateral or contralateral to the somatosensory stimulation which elicits the SEPs. In four experiments, the locus and selectivity of the SEPs' modulation, the contribution of cutaneous afferents and the effect of contraction magnitude were examined, respectively. A control condition where subjects had no task to perform was compared to several task conditions. The amplitude of the frontal N30, parietal P30, and central P25 was decreased and that of the long latency P80 and N140 was increased when the somatosensory stimuli triggered a voluntary movement of the stimulated finger compared to the control condition. The N60 decreased with the movement of any finger. These results were considered to be caused by the centrifugal influence of neuronal activity which occurs before a somatosensory imperative stimulus. The present findings did not support the hypothesis that the inhibition of afferent inputs by descending motor commands can occur at subcortical levels. A higher contraction magnitude produced a further attenuation of the amplitude of the frontal N30, while it decreased the enhancement of the P80. Moreover, the modulation of neuronal responses seems to result mainly from the modulation of cutaneous afferents, especially from the moved body parts. In conclusion, the short- and long-latency somatosensory neuronal activities

  14. Environmental Stewardship: How Semiconductor Suppliers Help toMeet Energy-Efficiency Regulations and Voluntary Specifications inChina

    Energy Technology Data Exchange (ETDEWEB)

    Aizhen, Li; Fanara, Andrew; Fridley, David; Merriman, Louise; Ju,Jeff

    2007-01-15

    Recognizing the role that semiconductor suppliers can playin meeting energy-efficiency regulations and voluntary specifications,this paper provides an overview of Chinese policies and implementingbodies; a discussion of current programs, their goals, and effectiveness;and possible steps that can be taken tomeet these energy-efficiencyrequirements while also meeting products' high performance and costgoals.

  15. Effects of the plant growth regulator, chlormequat, on mammalian fertility.

    Science.gov (United States)

    Sørensen, Martin T; Danielsen, Viggo

    2006-02-01

    This paper summarizes the consequences of exposure to chlormequat, a plant growth regulator, on reproduction in mammals. Plant growth regulators are chemicals used to manipulate plant growth, flowering and fruit yield. In grain crops, plant growth regulators are applied to promote sturdier growth and reduce the risk of lodging. Chlormequat is the most common plant growth regulator. Maximum residue limits of chlormequat in food products are 10 mg/kg in oat and pear, 3 mg/kg in wheat and rye, and 0.5 mg/kg in milk. In Denmark, results from experiments with pigs in the late 1980s showed sows that display impaired reproduction, mainly impaired oestrus, when fed grain from crop treated with chlormequat. Subsequently, the advisory body to the Danish pig industry recommended limiting the use of grain (maximum 30% of diet energy) from crop treated with chlormequat given to breeding stock due to the risk of reproduction problems. More recently, experiments have been conducted to evaluate the influence of chlormequat-treated wheat crop on reproductive function in male and female mice. These experiments showed that epididymal spermatozoa from mice on feed or water containing chlormequat had compromised fertilizing competence in vitro, while reproduction in female mice was not compromised. The estimated intake of chlormequat in the pig (0.0023 mg/kg bw/day) and the mouse (0.024 mg/kg bw/day) experiments was below the acceptable daily intake of 0.05 mg/kg bw/day. Reports from the industry do not show any effects at these low levels.

  16. Lin28a regulates germ cell pool size and fertility.

    Science.gov (United States)

    Shinoda, Gen; De Soysa, T Yvanka; Seligson, Marc T; Yabuuchi, Akiko; Fujiwara, Yuko; Huang, Pei Yi; Hagan, John P; Gregory, Richard I; Moss, Eric G; Daley, George Q

    2013-05-01

    Overexpression of LIN28A is associated with human germ cell tumors and promotes primordial germ cell (PGC) development from embryonic stem cells in vitro and in chimeric mice. Knockdown of Lin28a inhibits PGC development in vitro, but how constitutional Lin28a deficiency affects the mammalian reproductive system in vivo remains unknown. Here, we generated Lin28a knockout (KO) mice and found that Lin28a deficiency compromises the size of the germ cell pool in both males and females by affecting PGC proliferation during embryogenesis. Interestingly however, in Lin28a KO males, the germ cell pool partially recovers during postnatal expansion, while fertility remains impaired in both males and females mated to wild-type mice. Embryonic overexpression of let-7, a microRNA negatively regulated by Lin28a, reduces the germ cell pool, corroborating the role of the Lin28a/let-7 axis in regulating the germ lineage. Copyright © 2013 AlphaMed Press.

  17. Future regulation of fertility banking in the UK.

    Science.gov (United States)

    Hartshorne, Geraldine

    2003-05-01

    The storage of embryos and mature gametes is regulated by the Human Fertilisation and Embryology Authority (HFEA) and the laboratories concerned are generally in assisted conception centres. The HFEA does not regulate storage of immature gametes, such as oocytes in ovarian cortex, where no mature gametes are present. Under the Department of Health Code of Practice on Tissue Banking, since 1 April 2003, immature gametes must be stored in accredited tissue banks only. Most IVF units are unable to comply with this code, and many have stopped storing ovarian tissue. In the future, when patients request transplantation of tissue stored in non-accredited banks, individual Trusts will decide whether it is safe to be used. The Department of Health Code of Practice does not apply to mature gametes and embryos. Consequently, these may now be stored in conditions less stringent than those of other tissues used therapeutically. However, an EU directive covering all banked tissues used in therapy, specifically including gametes, embryos and stem cells, may soon eliminate this inconsistency. The standards used in fertility banking must therefore be improved if current practice in embryo and gamete cryopreservation is to continue. This article examines the present situation and the issues raised.

  18. Telemetric analysis of haemodynamic regulation during voluntary exercise training in mouse models

    Science.gov (United States)

    Danson, E. J.; Zhang, M. H.; Casadei, B.; Paterson, D. J.; Channon, K. M.

    2017-01-01

    Regular physical exercise reduces the risk of cardiovascular disease and improves outcome in patients with cardiovascular diseases. The dynamic changes in blood pressure and heart rate with acute exercise are independently predictive of prognosis. Quantification of the haemodynamic response to exercise training in genetically modified mouse models may provide insight into the molecular mechanisms underlying the beneficial effects of exercise. We describe, for the first time, the use of radiotelemetry to provide continuous blood pressure monitoring in C57BL/6J mice during a programme of voluntary wheel exercise with continuous simultaneous recording and analysis of wheel rotations and beat-by-beat haemodynamic parameters. We define distinct haemodynamic profiles at rest, during normal cage activity and during episodes of voluntary wheel running. We show that whilst cage activity is associated with significant rises both in blood pressure and in heart rate, voluntary wheel running leads to a further substantial rise in heart rate with only a small increment in blood pressure. With 5 weeks of chronic exercise training, resting heart rate progressively falls, but heart rate during episodes of wheel running initially increases. In contrast, there are minimal changes in blood pressure in response to chronic exercise training. Finally, we have quantified the acute changes in heart rate at the onset of and recovery from individual episodes of wheel running, revealing that changes in heart rate are extremely rapid and that the peak rate of change of heart rate increases with chronic exercise training. The results of this study have important implications for the use of genetically modified mouse models to investigate the beneficial haemodynamic effects of chronic exercise on blood pressure and cardiovascular diseases. PMID:21824998

  19. Role of the Dorsal Medial Habenula in the Regulation of Voluntary Activity, Motor Function, Hedonic State, and Primary Reinforcement

    Science.gov (United States)

    Hsu, Yun-Wei A.; Wang, Si D.; Wang, Shirong; Morton, Glenn; Zariwala, Hatim A.; de la Iglesia, Horacio O.

    2014-01-01

    The habenular complex in the epithalamus consists of distinct regions with diverse neuronal populations. Past studies have suggested a role for the habenula in voluntary exercise motivation and reinforcement of intracranial self-stimulation but have not assigned these effects to specific habenula subnuclei. Here, we have developed a genetic model in which neurons of the dorsal medial habenula (dMHb) are developmentally eliminated, via tissue-specific deletion of the transcription factor Pou4f1 (Brn3a). Mice with dMHb lesions perform poorly in motivation-based locomotor behaviors, such as voluntary wheel running and the accelerating rotarod, but show only minor abnormalities in gait and balance and exhibit normal levels of basal locomotion. These mice also show deficits in sucrose preference, but not in the forced swim test, two measures of depression-related phenotypes in rodents. We have also used Cre recombinase-mediated expression of channelrhodopsin-2 and halorhodopsin to activate dMHb neurons or silence their output in freely moving mice, respectively. Optical activation of the dMHb in vivo supports intracranial self-stimulation, showing that dMHb activity is intrinsically reinforcing, whereas optical silencing of dMHb outputs is aversive. Together, our findings demonstrate that the dMHb is involved in exercise motivation and the regulation of hedonic state, and is part of an intrinsic reinforcement circuit. PMID:25143617

  20. Role of the dorsal medial habenula in the regulation of voluntary activity, motor function, hedonic state, and primary reinforcement.

    Science.gov (United States)

    Hsu, Yun-Wei A; Wang, Si D; Wang, Shirong; Morton, Glenn; Zariwala, Hatim A; de la Iglesia, Horacio O; Turner, Eric E

    2014-08-20

    The habenular complex in the epithalamus consists of distinct regions with diverse neuronal populations. Past studies have suggested a role for the habenula in voluntary exercise motivation and reinforcement of intracranial self-stimulation but have not assigned these effects to specific habenula subnuclei. Here, we have developed a genetic model in which neurons of the dorsal medial habenula (dMHb) are developmentally eliminated, via tissue-specific deletion of the transcription factor Pou4f1 (Brn3a). Mice with dMHb lesions perform poorly in motivation-based locomotor behaviors, such as voluntary wheel running and the accelerating rotarod, but show only minor abnormalities in gait and balance and exhibit normal levels of basal locomotion. These mice also show deficits in sucrose preference, but not in the forced swim test, two measures of depression-related phenotypes in rodents. We have also used Cre recombinase-mediated expression of channelrhodopsin-2 and halorhodopsin to activate dMHb neurons or silence their output in freely moving mice, respectively. Optical activation of the dMHb in vivo supports intracranial self-stimulation, showing that dMHb activity is intrinsically reinforcing, whereas optical silencing of dMHb outputs is aversive. Together, our findings demonstrate that the dMHb is involved in exercise motivation and the regulation of hedonic state, and is part of an intrinsic reinforcement circuit.

  1. Differential regulation of MeCP2 and PP1 in passive or voluntary administration of cocaine or food.

    Science.gov (United States)

    Bodetto, Sarah Pol; Romieu, Pascal; Sartori, Maxime; Tesone-Coelho, Carolina; Majchrzak, Monique; Barbelivien, Alexandra; Zwiller, Jean; Anglard, Patrick

    2014-12-01

    Cocaine exposure induces changes in the expression of numerous genes, in part through epigenetic modifications. We have initially shown that cocaine increases the expression of the chromatin remodeling protein methyl-CpG binding protein 2 (MeCP2) and characterized the protein phosphatase-1Cβ (PP1Cβ) gene, as repressed by passive i.p. cocaine injections through a Mecp2-mediated mechanism involving de novo DNA methylation. Both proteins being involved in learning and memory processes, we investigated whether voluntary cocaine administration would similarly affect their expression using an operant self-administration paradigm. Passive and voluntary i.v. cocaine intake was found to induce Mecp2 and to repress PP1Cβ in the prefrontal cortex and the caudate putamen. This observation is consistent with the role of Mecp2 acting as a transcriptional repressor of PP1Cβ and shows that passive intake was sufficient to alter their expression. Surprisingly, striking differences were observed under the same conditions in food-restricted rats tested for food pellet delivery. In the prefrontal cortex and throughout the striatum, both proteins were induced by food operant conditioning, but remained unaffected by passive food delivery. Although cocaine and food activate a common reward circuit, changes observed in the expression of other genes such as reelin and GAD67 provide new insights into molecular mechanisms differentiating neuroadaptations triggered by each reinforcer. The identification of hitherto unknown genes differentially regulated by drugs of abuse and a natural reinforcer should improve our understanding of how two rewarding stimuli differ in their ability to drive behavior.

  2. Fibroblast growth factor 21 has no direct role in regulating fertility in female mice

    Directory of Open Access Journals (Sweden)

    Garima Singhal

    2016-08-01

    Conclusions: We conclude that FGF21 is not a direct physiological regulator of fertility in mice. The infertility observed in FGF21 overexpressing mice is likely driven by the increased energy expenditure and consequent excess calorie requirements resulting from high FGF21 levels.

  3. Additional nitrogen fertilization at heading time of rice down-regulates cellulose synthesis in seed endosperm.

    Science.gov (United States)

    Midorikawa, Keiko; Kuroda, Masaharu; Terauchi, Kaede; Hoshi, Masako; Ikenaga, Sachiko; Ishimaru, Yoshiro; Abe, Keiko; Asakura, Tomiko

    2014-01-01

    The balance between carbon and nitrogen is a key determinant of seed storage components, and thus, is of great importance to rice and other seed-based food crops. To clarify the influence of the rhizosphere carbon/nitrogen balance during the maturation stage of several seed components, transcriptome analysis was performed on the seeds from rice plants that were provided additional nitrogen fertilization at heading time. As a result, it was assessed that genes associated with molecular processes such as photosynthesis, trehalose metabolism, carbon fixation, amino acid metabolism, and cell wall metabolism were differentially expressed. Moreover, cellulose and sucrose synthases, which are involved in cellulose synthesis, were down-regulated. Therefore, we compared cellulose content of mature seeds that were treated with additional nitrogen fertilization with those from control plants using calcofluor staining. In these experiments, cellulose content in endosperm from plants receiving additional nitrogen fertilization was less than that in control endosperm. Other starch synthesis-related genes such as starch synthase 1, starch phosphorylase 2, and branching enzyme 3 were also down-regulated, whereas some α-amylase and β-amylase genes were up-regulated. On the other hand, mRNA expression of amino acid biosynthesis-related molecules was up-regulated. Moreover, additional nitrogen fertilization caused accumulation of storage proteins and up-regulated Cys-poor prolamin mRNA expression. These data suggest that additional nitrogen fertilization at heading time changes the expression of some storage substance-related genes and reduces cellulose levels in endosperm.

  4. Genetics of mammalian meiosis: regulation, dynamics and impact on fertility.

    Science.gov (United States)

    Handel, Mary Ann; Schimenti, John C

    2010-02-01

    Meiosis is an essential stage in gamete formation in all sexually reproducing organisms. Studies of mutations in model organisms and of human haplotype patterns are leading to a clearer understanding of how meiosis has adapted from yeast to humans, the genes that control the dynamics of chromosomes during meiosis, and how meiosis is tied to gametic success. Genetic disruptions and meiotic errors have important roles in infertility and the aetiology of developmental defects, especially aneuploidy. An understanding of the regulation of meiosis, coupled with advances in genomics, may ultimately allow us to diagnose the causes of meiosis-based infertilities, more wisely apply assisted reproductive technologies, and derive functional germ cells.

  5. Voluntary exercise prevents colonic inflammation in high-fat diet-induced obese mice by up-regulating PPAR-γ activity

    Energy Technology Data Exchange (ETDEWEB)

    Liu, Wei-Xin, E-mail: weixinliu@yahoo.com [Department of Gastroenterology, First Affiliated Hospital of China Medical University, Shenyang 110001, Liaoning (China); Wang, Ting; Zhou, Feng; Wang, Ying; Xing, Jun-Wei; Zhang, Shen [Department of Gastroenterology, First Affiliated Hospital of China Medical University, Shenyang 110001, Liaoning (China); Gu, Shou-Zhi [Department of Anatomy, Seirei Christopher College, Hamamatsu 433-8558 (Japan); Sang, Li-Xuan [Department of Cadre Ward II, First Affiliated Hospital of China Medical University, Shenyang 110001, Liaoning (China); Dai, Cong [Department of Gastroenterology, First Affiliated Hospital of China Medical University, Shenyang 110001, Liaoning (China); Wang, Hai-Lan [Guangdong Province Hospital for Occupational Disease Prevention and Treatment, Guangzhou 510300, Guangdong (China)

    2015-04-10

    Obesity is associated with increased colonic inflammation, which elevates the risk of colon cancer. Although exercise exerts anti-inflammatory actions in multiple chronic diseases associated with inflammation, it is unknown whether this strategy prevents colonic inflammation in obesity. We hypothesized that voluntary exercise would suppress colonic inflammation in high-fat diet (HFD)-induced obesity by modulation of peroxisome proliferator-activated receptor (PPAR)-γ. Male C57Bl/6J mice fed either a control diet (6.5% fat, CON) or a high-fat diet (24% fat, HFD) were divided into sedentary, voluntary exercise or voluntary exercise with PPAR-γ antagonist GW9662 (10 mg/kg/day). All interventions took place for 12 weeks. Compared with CON-sedentary group, HFD-sedentary mice gained significantly more body weight and exhibited metabolic disorders. Molecular studies revealed that HFD-sedentary mice had increased expression of inflammatory mediators and activation of nuclear factor (NF)-κB in the colons, which were associated with decreased expression and activity of PPAR-γ. Voluntary exercise markedly attenuated body weight gain, improved metabolic disorders, and normalized the expression of inflammatory mediators and activation of NF-κB in the colons in HFD-mice while having no effects in CON-animals. Moreover, voluntary exercise significantly increased expression and activity of PPAR-γ in the colons in both HFD- and CON-animals. However, all of these beneficial effects induced by voluntary exercise were abolished by GW9662, which inhibited expression and activity of PPAR-γ. The results suggest that decreased PPAR-γ activity in the colon of HFD-induced obesity may facilitate the inflammatory response and colon carcinogenesis. Voluntary exercise prevents colonic inflammation in HFD-induced obesity by up-regulating PPAR-γ activity. - Highlights: • Obesity down-regulates PPAR-γ in the colon. • Down-regulated colonic PPAR-γ may facilitate inflammatory

  6. Towards an integrated design of voluntary approaches and standardization processes: An analysis of issues and trends in the Italian regulation on ground coupled heat pumps

    Energy Technology Data Exchange (ETDEWEB)

    Rizzi, Francesco, E-mail: f.rizzi@sssup.it [Scuola Superiore Sant' Anna - Istituto di Management, P.zza Martiri della Liberta 33, 56127 Pisa (Italy); Frey, Marco, E-mail: frey@sssup.it [Scuola Superiore Sant' Anna - Istituto di Management, P.zza Martiri della Liberta 33, 56127 Pisa (Italy); Iraldo, Fabio, E-mail: f.iraldo@sssup.it [Scuola Superiore Sant' Anna - Istituto di Management, P.zza Martiri della Liberta 33, 56127 Pisa (Italy)

    2011-09-15

    Highlights: {yields} We investigate GCHP regulation development from an entrepreneurial perspective. {yields} Threats in booming market orient entrepreneurs toward green management. {yields} Command and control regulation is not sufficient to guarantee market sustainability. {yields} Voluntary regulation encourage best performers to invest in long-term strategies. {yields} Bottom-up regulation design advances integration of process and product standards. - Abstract: Despite the lack of specific incentives, ground coupled heat pump (GCHP) installations are booming in Italy both in the private and public sectors. Such rapid growth is coupled with increasing concern for environmental and technical performances since no comprehensive regulation and reliable standards currently exist. This paper discusses potential schemes aimed at balancing mandatory and voluntary requirements by using SWOT-based techniques and examining the opinions of sectoral leaders. The analysis suggests that standardization and voluntary schemes are perceived as efficient and effective tools to encourage the greening of Italian GCHP-SMEs in the short-term while laying the foundations for sustainable policies in the longer run. A potential scheme is discussed that was simulated by reflecting the supply-side of the market, and which involves process and product standards.

  7. [IMPACT OF INDIVIDUAL PERSONALITY FEATURES ON ABILITY TO VOLUNTARY REGULATION OF EXPRESSION EEG ALPHA AND BETA FREQUENCIES].

    Science.gov (United States)

    Aslanyan, E V; Kiroy, V N; Stoletniy, A S; Lazurenko, D M; Bahtin, O M; Minyaeva, N R; Kiroy, R I

    2015-05-01

    The ability to voluntary control severity of alpha- and beta-2 frequency bands in the parietal and frontal cortical areas was investigated at 17 volunteers using biofeedback. The impact of different personality traits on the effectiveness of control was evaluated. According to the data, it was easier task to decrease expression beta-2 frequency in the frontal cortex than to decline the power of alpha frequency in the parietal cortex. The effectiveness of voluntary control of brain activity is influenced by personality features as extraversion, psychoticism, neuroticism, mobility and steadiness of nerve processes, level of person anxiety.

  8. The Self-Regulation Effect of Fertility Status on Inbreeding Aversion: When Fertile, Disgust Increases more in Response to Descriptions of One's Own than of Others' Inbreeding

    Directory of Open Access Journals (Sweden)

    Jan Antfolk

    2014-07-01

    Full Text Available The ovulatory shift modulates emotions related to female sexuality. Because fertility status only affects the individual's own opportunity cost, the adaptive value of this shift is expected to stem from self-regulation. To test this assumption we asked women to contemplate various inbreeding descriptions: 1 they themselves having sex with male relatives; 2 their sister having sex with their common male relatives; and 3 an unrelated woman having sex with her male relatives (in 1, but not 2 and 3, negative fitness consequences are affected by the participant's fertility. We dichotomized the dependent variable disgust (ceiling vs. non-ceiling and analyzed the interaction between fertility status and description type. The ovulatory shift was stronger in descriptions where they themselves were described as engaging in inbreeding. A smaller increase was also found in reactions to others engaging in inbreeding. We explain the latter effect as due to self-reflection.

  9. Voluntary Slavery

    Directory of Open Access Journals (Sweden)

    Danny Frederick

    2014-06-01

    Full Text Available The permissibility of actions depends upon facts about the flourishing and separateness of persons. Persons differ from other creatures in having the task of discovering for themselves, by conjecture and refutation, what sort of life will fulfil them. Compulsory slavery impermissibly prevents some persons from pursuing this task. However, many people may conjecture that they are natural slaves. Some of these conjectures may turn out to be correct. In consequence, voluntary slavery, in which one person welcomes the duty to fulfil all the commands of another, is permissible. Life-long voluntary slavery contracts are impermissible because of human fallibility; but fixed-term slavery contracts should be legally enforceable. Each person has the temporarily alienable moral right to direct her own life.

  10. Voluntary Slavery

    Directory of Open Access Journals (Sweden)

    Danny Frederick

    2014-06-01

    Full Text Available The permissibility of actions depends upon facts about the flourishing and separateness of persons. Persons differ from other creatures in having the task of discovering for themselves, by conjecture and refutation, what sort of life will fulfil them. Compulsory slavery impermissibly prevents some persons from pursuing this task. However, many people may conjecture that they are natural slaves. Some of these conjectures may turn out to be correct. In consequence, voluntary slavery, in which one person welcomes the duty to fulfil all the commands of another, is permissible. Life-long voluntary slavery contracts are impermissible because of human fallibility; but fixed-term slavery contracts should be legally enforceable. Each person has the temporarily alienable moral right to direct her own life.

  11. Cytisine modulates chronic voluntary ethanol consumption and ethanol-induced striatal up-regulation of ΔFosB in mice.

    Science.gov (United States)

    Sajja, Ravi Kiran; Rahman, Shafiqur

    2013-06-01

    Chronic administration of ethanol induces persistent accumulation of ΔFosB, an important transcription factor, in the midbrain dopamine system. This process underlies the progression to addiction. Previously, we have shown that cytisine, a neuronal nicotinic acetylcholine receptor (nAChR) partial agonist, reduces various ethanol-drinking behaviors and ethanol-induced striatal dopamine function. However, the effects of cytisine on chronic ethanol drinking and ethanol-induced up-regulation of striatal ΔFosB are not known. Therefore, we examined the effects of cytisine on chronic voluntary ethanol consumption and associated striatal ΔFosB up-regulation in C57BL/6J mice using behavioral and biochemical methods. Following the chronic voluntary consumption of 15% (v/v) ethanol under a 24-h two-bottle choice intermittent access (IA; 3 sessions/week) or continuous access (CA; 24 h/d and 7 d/week) paradigm, mice received repeated intraperitoneal injections of saline or cytisine (0.5 or 3.0 mg/kg). Ethanol and water intake were monitored for 24 h post-treatment. Pretreatment with cytisine (0.5 or 1.5 mg/kg) significantly reduced ethanol consumption and preference in both paradigms at 2 h and 24 h post-treatment. The ΔFosB levels in the ventral and dorsal striatum were determined by Western blotting 18-24 h after the last point of ethanol access. In addition, cytisine (0.5 mg/kg) significantly attenuated up-regulation of ΔFosB in the ventral and dorsal striatum following chronic ethanol consumption in IA and CA paradigms. The results indicate that cytisine modulates chronic voluntary ethanol consumption and reduces ethanol-induced up-regulation of striatal ΔFosB. Further, the data suggest a critical role of nAChRs in chronic ethanol-induced neurochemical adaptations associated with ethanol addiction.

  12. KATNAL1 regulation of sertoli cell microtubule dynamics is essential for spermiogenesis and male fertility.

    Directory of Open Access Journals (Sweden)

    Lee B Smith

    Full Text Available Spermatogenesis is a complex process reliant upon interactions between germ cells (GC and supporting somatic cells. Testicular Sertoli cells (SC support GCs during maturation through physical attachment, the provision of nutrients, and protection from immunological attack. This role is facilitated by an active cytoskeleton of parallel microtubule arrays that permit transport of nutrients to GCs, as well as translocation of spermatids through the seminiferous epithelium during maturation. It is well established that chemical perturbation of SC microtubule remodelling leads to premature GC exfoliation demonstrating that microtubule remodelling is an essential component of male fertility, yet the genes responsible for this process remain unknown. Using a random ENU mutagenesis approach, we have identified a novel mouse line displaying male-specific infertility, due to a point mutation in the highly conserved ATPase domain of the novel KATANIN p60-related microtubule severing protein Katanin p60 subunit A-like1 (KATNAL1. We demonstrate that Katnal1 is expressed in testicular Sertoli cells (SC from 15.5 days post-coitum (dpc and that, consistent with chemical disruption models, loss of function of KATNAL1 leads to male-specific infertility through disruption of SC microtubule dynamics and premature exfoliation of spermatids from the seminiferous epithelium. The identification of KATNAL1 as an essential regulator of male fertility provides a significant novel entry point into advancing our understanding of how SC microtubule dynamics promotes male fertility. Such information will have resonance both for future treatment of male fertility and the development of non-hormonal male contraceptives.

  13. Effect of bio-regulator and foliar fertilizers on chemical composition and yield of soybean.

    Science.gov (United States)

    Piccinin, Gleberson Guillen; Braccini, Alessandro Lucca; da Silva, Luiz Henrique; Mariucci, Giovanna Emanuêlle Gonçalves; Suzukawa, Andréia Kazumi; Dan, Lilian Gomes de Morais; Tonin, Telmo António

    2013-11-15

    Current study evaluates the effects of bio-regulator associated with foliar fertilizers on the yield components, productivity and chemical composition of soybean. The experimental design was entirely randomized blocks, with four replications. The treatments consisted of: T1-absolute control, T2-application of 0.25 L h(-1) Stimulate in R1 stage of development, T3-application of 0.25 L h(-1) Stimulate and 3 L h(-1) Sett in R1, T4-application of 0.25 L h(-1) Stimulate and 3 L h(-1) Sett in R1 and 0.25 L h(-1) Stimulate and 2 L h(-1) Mover in R5.1; T5-application of 0.25 L h(-1) Stimulate and 3 L h(-1) Sett in R1 and 2 L h(-1) Mover in R5.1, T6-application of 3 L h(-1) Sett in R1 and 0.25 L h(-1) Stimulate and 2 L h(-1) Mover in R5.1 and T7-application of 0.25 L h(-1) Stimulate and 2 L h(-1) Mover in R1. Application of Sett and Mover is a potentially efficient handling as it favors the soybean agronomic performance in R1 stage. Chemical composition of processed grains has influence with applying bio-regulator and foliar fertilizers.

  14. [[Trends in marriage and fertility in Japan: major findings from the Tenth Japanese National Fertility Survey

    Science.gov (United States)

    Atoh, M; Takahashi, S; Nakano, E; Watanabe, Y; Kojima, H; Kaneko, R

    1993-10-01

    The authors review trends in marriage and fertility in Japan, using data from the 1993 Japanese National Fertility Survey. Information is included on age at marriage, arranged and voluntary marriages, length of time from initial meeting to marriage, changes in age at marriage, fertility, socioeconomic differentials in fertility, and fertility preferences. (SUMMARY IN ENG)

  15. The role of women's employment programmes in influencing fertility regulation in rural Bangladesh.

    Science.gov (United States)

    Mahmud, S

    1994-01-01

    This study compares fertility control among women participating in income-generation programs and among a socioeconomically similar comparison group in Bangladesh. Interviews were conducted among a sample of about 100 currently married women from each of four income-generation programs in Bangladesh: the government's Women's Program of the Bangladesh Rural Development Board (BRDB), the Women's Entrepreneurship Development Program of Bangladesh's Small and Cottage Industries Corporation (BSCIC), the Grameen Bank, and the Bangladesh Rural Advancement Committee (BRAC) Women's Program. There were 417 women in the sample and 389 women in the comparison group. These programs provided credit to women for activities, such as paddy husking and poultry keeping. The BSCIC did not provide any direct or indirect family planning input. The BRDB encouraged women to use modern contraceptives. The Grameen and BRAC educated participants about the benefits of small families. Three groups, with the exception of BRAC, used women's groups. The sample group had almost eight times the average household income of the comparison group. About 20% of the sample group were engaged in nontraditional activities. Almost 20% worked outside the home. 18% were engaged in wage work. Over 40% worked more than 5 hours per day. 75% were members of informal groups. The sample and comparison groups differed in the context of productive work and contraceptive use. Multivariate findings show strong support for the direct and significant effect of employment programs on fertility-regulating behavior of poor respondents. Nongovernmental groups with a women's group approach were more effective in raising income levels and physical mobility. The BSCIC had much lower contraceptive prevalence. Program participants had higher sterilization rates, but actual fertility was also higher.

  16. How do mineral fertilization and plant growth regulators affect yield and morphology of naked oat?

    Directory of Open Access Journals (Sweden)

    Robert Witkowicz

    2010-09-01

    Full Text Available Oat (Avena sativa var. nuda is of an increasing interest in many parts of the world. This is why plant breeders have developed forms that are morphologically different from the current ones, such as naked, dwarf or with an increased 1000-grain-weight. In three experiments conducted at two sites, the influence of phosphorus (P and potassium (K fertilizers, spray application of urea and spray application of plant growth regulators (PGRs Promalin (gibberellins + cytokinin and Moddus (cimectacarps on the yield and morphological traits of different oat forms were studied. At a better site, only genotype statistically influenced oat grain yield. At a poorer site, apart from genotype there were statistically significant responses to P and K fertilizers and to the application of Moddus (especially in the experiment with a dwarf cultivar. The internode and panicle length were modified mostly by cimectacarps, which shortened specific internodes, but not the panicle. The PGR Promalin had no significant effect on oat stem morphology.

  17. FGF signaling supports Drosophila fertility by regulating development of ovarian muscle tissues.

    Science.gov (United States)

    Irizarry, Jihyun; Stathopoulos, Angelike

    2015-08-01

    The thisbe (ths) gene encodes a Drosophila fibroblast growth factor (FGF), and mutant females are viable but sterile suggesting a link between FGF signaling and fertility. Ovaries exhibit abnormal morphology including lack of epithelial sheaths and muscle tissues that surround ovarioles. Here we investigated how FGF influences Drosophila ovary morphogenesis and identified several roles. Heartless (Htl) FGF receptor was found to be expressed within somatic cells at the larval and pupal stages, and phenotypes were uncovered using RNAi. Differentiation of terminal filament cells was affected, but this effect did not alter the ovariole number. In addition, proliferation of epithelial sheath progenitors, the apical cells, was decreased in both htl and ths mutants, while ectopic expression of the Ths ligand led to these cells' over-proliferation suggesting that FGF signaling supports ovarian muscle sheath formation by controlling apical cell number in the developing gonad. Additionally, live imaging of adult ovaries was used to show that htl RNAi mutants, hypomorphic mutants in which epithelial sheaths are present, exhibit abnormal muscle contractions. Collectively, our results demonstrate that proper formation of ovarian muscle tissues is regulated by FGF signaling in the larval and pupal stages through control of apical cell proliferation and is required to support fertility.

  18. Enhancing crop yield with the use of N-based fertilizers co-applied with plant hormones or growth regulators.

    Science.gov (United States)

    Zaman, Mohammad; Kurepin, Leonid V; Catto, Warwick; Pharis, Richard P

    2015-07-01

    Crop yield, vegetative or reproductive, depends on access to an adequate supply of essential mineral nutrients. At the same time, a crop plant's growth and development, and thus yield, also depend on in situ production of plant hormones. Thus optimizing mineral nutrition and providing supplemental hormones are two mechanisms for gaining appreciable yield increases. Optimizing the mineral nutrient supply is a common and accepted agricultural practice, but the co-application of nitrogen-based fertilizers with plant hormones or plant growth regulators is relatively uncommon. Our review discusses possible uses of plant hormones (gibberellins, auxins, cytokinins, abscisic acid and ethylene) and specific growth regulators (glycine betaine and polyamines) to enhance and optimize crop yield when co-applied with nitrogen-based fertilizers. We conclude that use of growth-active gibberellins, together with a nitrogen-based fertilizer, can result in appreciable and significant additive increases in shoot dry biomass of crops, including forage crops growing under low-temperature conditions. There may also be a potential for use of an auxin or cytokinin, together with a nitrogen-based fertilizer, for obtaining additive increases in dry shoot biomass and/or reproductive yield. Further research, though, is needed to determine the potential of co-application of nitrogen-based fertilizers with abscisic acid, ethylene and other growth regulators.

  19. 14 CFR 234.7 - Voluntary reporting.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 4 2010-01-01 2010-01-01 false Voluntary reporting. 234.7 Section 234.7 Aeronautics and Space OFFICE OF THE SECRETARY, DEPARTMENT OF TRANSPORTATION (AVIATION PROCEEDINGS) ECONOMIC REGULATIONS AIRLINE SERVICE QUALITY PERFORMANCE REPORTS § 234.7 Voluntary reporting. (a) In addition to the...

  20. Regulation proposal for voluntary energy efficiency labelling of commercial buildings; Regulamentacao de etiquetagem voluntaria de nivel de eficiencia energetica de edificios comerciais e publicos

    Energy Technology Data Exchange (ETDEWEB)

    Lamberts, Roberto; Goulart, Solange; Carlo, Joyce; Westphal, Fernando [Universidade Federal de Santa Catarina (UFSC/LabEEE), Florianopolis, SC (Brazil). Lab. de Eficiencia Energetica em Edificacoes], e-mail: lamberts@ecv.ufsc.br, e-mail: solange@labeee.ufsc.br, e-mail: joyce@labeee.ufsc.br, e-mail: fernando@labeee.ufsc.br

    2006-07-01

    Despite of Brazil not being between the major world energy consumers, the consumption of electricity has significantly increased in the late years. The National Energy Balance of 2005, published by the Brazilian Ministry of Energy, showed an increasing of the participation of electricity in the final energy consumption of 15.7% in 2002 to 16.2% in 2004. Initially, a brief review of the initiatives taken by Brazilian Government aiming to limit and control the energy consumption in buildings is presented. Then, the regulation proposal containing the technical requirements to classify the energy efficiency level of buildings is shown. The purpose of this voluntary regulation is to provide conditions to certify the energy efficiency level of Brazilian buildings (commercial and public). It specifies the methods for energy efficiency rating of buildings and includes requirements to attend energy conservation measures in three main issues: lighting system; air conditioning system and envelope. The regulation applies to large buildings (minimum total area of 500 m{sup 2} or when the energy demand is greater than or equal to 2,3 kV, including: Conditioned buildings; Partially conditioned buildings and Naturally ventilated buildings. (author)

  1. The endocytic recycling regulator EHD1 is essential for spermatogenesis and male fertility in mice

    Directory of Open Access Journals (Sweden)

    Hess Rex A

    2010-04-01

    Full Text Available Abstract Background The C-terminal Eps15 homology domain-containing protein 1 (EHD1 is ubiquitously expressed and regulates the endocytic trafficking and recycling of membrane components and several transmembrane receptors. To elucidate the function of EHD1 in mammalian development, we generated Ehd1-/- mice using a Cre/loxP system. Results Both male and female Ehd1-/- mice survived at sub-Mendelian ratios. A proportion of Ehd1-/- mice were viable and showed smaller size at birth, which continued into adulthood. Ehd1-/- adult males were infertile and displayed decreased testis size, whereas Ehd1-/- females were fertile. In situ hybridization and immunohistochemistry of developing wildtype mouse testes revealed EHD1 expression in most cells of the seminiferous epithelia. Histopathology revealed abnormal spermatogenesis in the seminiferous tubules and the absence of mature spermatozoa in the epididymides of Ehd1-/- males. Seminiferous tubules showed disruption of the normal spermatogenic cycle with abnormal acrosomal development on round spermatids, clumping of acrosomes, misaligned spermatids and the absence of normal elongated spermatids in Ehd1-/- males. Light and electron microscopy analyses indicated that elongated spermatids were abnormally phagocytosed by Sertoli cells in Ehd1-/- mice. Conclusions Contrary to a previous report, these results demonstrate an important role for EHD1 in pre- and post-natal development with a specific role in spermatogenesis.

  2. Male fertility and apoptosis in normal spermatogenesis are regulated by vacuolar-ATPase isoform a2.

    Science.gov (United States)

    Jaiswal, Mukesh K; Agrawal, Varkha; Katara, Gajendra K; Pamarthy, Sahithi; Kulshrestha, Arpita; Chaouat, Gerard; Gilman-Sachs, Alice; Beaman, Kenneth D

    2015-11-01

    The a2 isoform of vacuolar-ATPase (ATP6V0A2, referred to as a2V) is required for normal spermatogenesis and maturation of sperm. Treatment of male mice with anti-a2V disturbs the testicular cytokine/chemokine balance and leads to severe deficiencies of spermatogenesis. The aim of the present study was to investigate the role of a2V in male fertility and in the regulation of apoptotic pathways required for normal spermatogenesis in mice. To study the role of a2V single dose of anti-a2V monoclonal antibody or mouse IgG isotype (3μg/animal) was injected i.p. into males on alternate days for 10 days. The expression of sperm maturation-related molecules and pro-apoptotic molecules was measured by real-time PCR or immunohistochemistry in control and anti-a2V-treated testes. The caspase levels and their activity were measured by western blot and fluorometry. We found that the expression of the sperm maturation-related molecules SPAM1, ADAM1, and ADAM2 was significantly decreased in testes from anti-a2V-treated males. The expression of pro-apoptotic molecules (Bax, p53, and p21) and molecules involved in the intrinsic pathway of apoptosis (caspase-9, caspase-3, and PARP), which are crucial for normal spermatogenesis was significantly reduced in testes from anti-a2V-treated males compared with the control. The total ATP level was significantly lower in anti-a2V-treated testes. The data provide novel evidence showing that a2V can regulate the apoptotic pathways, an essential testicular feature, and is necessary for efficient spermatogenesis.

  3. Finding the Right Touch: Extending the Right-Touch Regulation Approach to the Accreditation of Voluntary Registers

    Science.gov (United States)

    Bilton, Douglas; Cayton, Harry

    2013-01-01

    What is "right-touch regulation"? In this article we explain why the Professional Standards Authority for Health and Social Care (the Authority) has focussed much of its policy work in recent times on seeking an answer to this question, and why it wants to know. We explain why the Authority's predecessor body, the Council for Healthcare Regulatory…

  4. Voluntary Service System (VSS)

    Data.gov (United States)

    Department of Veterans Affairs — Voluntary Service System (VSS) is a national-level application which replaced the site-based Voluntary Timekeeping System (VTK). VTK was used for many years at the...

  5. Application of herbicides as growth regulators of emerald Zoysia grass fertilized with nitrogen

    Directory of Open Access Journals (Sweden)

    Raíssa Pereira Dinalli

    2015-07-01

    Full Text Available Nitrogen (N is essential for nutrition and for the maintenance of the intense green color of lawns. However, this element affects shoot growth and, therefore, mowing frequency, which is a key factor of lawn-maintenance costs. Accordingly, this study aimed to evaluate the use of nitrogen fertilization in combination with the use of potential herbicides as growth regulators to promote the maintenance of the high visual (intense green and nutritional quality of lawns of emerald Zoysia (Zoysia japonica Steud. grown in Ultisol soil while reducing their leaf growth. The experiment was conducted at the Teaching, Research and Extension Education Farm (Fazenda de Ensino, Pesquisa e Extensão of São Paulo State University (Universidade Estadual Paulista Júlio de Mesquita Filho, UNESP, Ilha Solteira Campus/ São Paulo (SP, from June/2012 to June/2013. The experimental design consisted of randomized blocks with 20 treatments established in a 5 x 4 factorial arrangement with four replicates, including four herbicides (glyphosate, imazaquin, imazethapyr, and metsulfuron-methyl, applied at doses of 200, 420, 80, and 140 g ha-1 active ingredient (a.i., respectively and a control (without herbicide, and four N doses (0, 5, 10, and 20 g m-2, split into five applications delivered throughout the year. The following items were evaluated: length, LCI (leaf chlorophyll index, leaf dry matter production and leaf N concentration and the percentage of phytotoxicity on lawn grass shoots. Doses from 10 to 20 g m-2 N provided sufficient N concentrations to maintain the emerald Zoysia. The herbicides metsulfuron-methyl and glyphosate were superior in the control of lawn leaf growth. While the former was phytotoxic, the latter had no effect on the aesthetic quality of the lawn, standing out as an herbicide that may be used at a dose of 200 g ha-1 toregulate the growth of emerald Zoysia.

  6. The Application of Billings for Fertility Regulation Method during the Period of Breastfeeding

    Institute of Scientific and Technical Information of China (English)

    金碧华; 姜国珠; 潘琢如; 颜洁敏; 彭守静; 陆仁康

    1999-01-01

    In order to adopt Billings Method for fertility regulation during the period of breast-feeding,cervical mucus was observed and monitored in 61 breast-feeding mothers.Urine estrogen and/or pregnanediol were/was measured in 15 breast feeding mothers.Observations on cervical mucus during 244 months were collected.The type of dry or no mucus was observed in 75.27% fully breast-feeding mothers.Constant unchanging mucus was ob-served in 69.39% partially breast-feeding mothers.Developmental changing mucus was observed in 79.25% of mothers bottle-feeding their infants.According to the record on cervical mucus within 6months postpartum,97.14% of the cervical mucus was consistent with normal menstrual cycles.Urine estrogen and /or pregnanediol were/was measured in 15 breast-feeding mothers.The level of estrogen in urine averaged 0.08 μmol/24 h in fully breast feeding mothers and 0.14 μmol/24 h in partially breast-feeding mothers.The peak level averaged 0.21 pmol/24 h in bottle-feeding mothers.The pregnanediol level was determined to confirm ovulation in bottle-feeding mothers.The average levels of cut off and the period of ovutation in 6bottle feeding mother were 7 μmol/24 h and 9 μmol/24 h respectively.Measurement of urine estrogen and pregnanediot level all matched with cervical mucus appearances.Conclusion: Billings Method is a simple,scientific method for contraception without side-effects during breast-feeding period.

  7. Easterlin's fertility theory and population adjustment and regulation in rural China.

    Science.gov (United States)

    Li, J

    1997-01-01

    The author considers some approaches which could be used to solve China's rural population problems through integrating Easterlin's fertility theory and certain characteristics of changes in China's rural population fertility. American demographer R.A. Easterlin conceptualized the meaning of fertility revolution with consideration of the overall modernization process. His theory is described. However, both effective family planning policies and attention to the impact of non-policy factors upon fertility changes are needed to resolve China's rural population problems. Community development and women's participation in Luo Chuan and Yong Shou, Shaanxi Province; the establishment of a social security support system for the elderly in Shandong Province; collective economy and rural urbanization in Southern Jiangsu Province; and improving the quality of family planning technical services are discussed.

  8. Management, regulation and environmental impacts of nitrogen fertilization in northwestern Europe under the Nitrates Directive

    DEFF Research Database (Denmark)

    van Grinsven, H.J.M.; ten Berge, H.F.M.; Dalgaard, Tommy;

    2012-01-01

    . Issues of concern and improvement of the implementation of the NiD are accounting for the fertilizer value of nitrogen in manure, and relating application limits for total nitrogen (N) to potential crop yield and N removal. The most significant environmental effect of the implementation of the NiD since....... This decrease is less prominent for groundwater in view of delayed response of nitrate in deep aquifers. In spite of improved fertilization practices, the southeast of the Netherlands, the Flemish Region and Brittany remain to be regions of major concern in view of a combination of a high nitrogen surplus, high...... reporting period for the NiD (2004–2007) and results of the MITERRA-EUROPE model. Implementation of the NiD in the considered member states is fairly comparable regarding restrictions for where and when to apply fertilizer and manure, but very different regarding application limits for N fertilization...

  9. Insights into the Regulation of Rhizosphere Bacterial Communities by Application of Bio-organic Fertilizer in Pseudostellaria heterophylla Monoculture Regime

    Directory of Open Access Journals (Sweden)

    Linkun Wu

    2016-11-01

    Full Text Available The biomass and quality of Pseudostellariae heterophylla suffers a significant decline under monoculture. Since rhizosphere microbiome plays crucial roles in soil health, deep pyrosequencing combined with qPCR was applied to characterize the composition and structure of soil bacterial community under monoculture and different amendments. The results showed compared with the first-year planted (FP, second-year monoculture of P. heterophylla (SP led to a significant decline in yield and resulted in a significant increase in Fusarium oxysporum but a decline in Burkholderia spp. Bio-organic fertilizer (MT formulated by combining antagonistic bacteria with organic matter could significantly promote the yield by regulating rhizosphere bacterial community. However, organic fertilizer (MO without antagonistic bacteria could not suppress Fusarium wilt. Multivariate statistics analysis showed a distinct separation between the healthy samples (FP and MT and the unhealthy samples (SP and MO, suggesting a strong relationship between soil microbial community and plant performance. Furthermore, we found the application of bio-organic fertilizer MT could significantly increase the bacterial community diversity and restructure microbial community with relatively fewer pathogenic F. oxysporum and more beneficial Burkholderia spp. In conclusion, the application of novel bio-organic fertilizer could effectively suppress Fusarium wilt by enriching the antagonistic bacteria and enhancing the bacterial diversity.

  10. [Effects of nitrogen regulators on fertilizer nitrogen transformation in meadow cinnamon soil and on pakchoi growth].

    Science.gov (United States)

    Sun, Zhi-Mei; Zhang, Kuo; Liu, Jian-Tao; Si, Huan-Sen; Wang, Yan-Qun

    2012-09-01

    Soil incubation test and pot experiment were conducted to investigate the effects of dicyandiamide (DCD) and its combination with nano-carbon on the transformation of fertilizers (urea and ammonium bicarbonate) nitrogen (N) in meadow cinnamon soil, a typical soil type in North China Plain, and on the growth of pakchoi (Brassica chinensis). In the first two weeks after applying urea and ammonium bicarbonate, the soil NH4+-N and NO3(-)-N contents varied greatly, but little variation was observed since then. The effects of the applied fertilizer N on the pakchoi growth and its N use efficiency differed significantly at early growth stages, but had little difference at harvesting stage. The DCD inhibited the transformation of the fertilizer N (especially ammonium bicarbonate N) into nitrate markedly, and this effect increased with increasing DCD dose. Under the conditions of our experiment, the optimal application rate of DCD was 1.0-1.5% of applied fertilize N, which could increase the pakchoi yield significantly, improve the leaf color, decrease the plant nitrate contents, and increase the fertilizer N use efficiency. The combination of DCD and nano-carbon exerted a synergistic effect on inhibiting soil ammonium oxidation, and also, promoted the pakchoi growth and N utilization at early growth stages significantly and decreased the plant nitrate level at harvesting stage.

  11. The Clinical Study on Effect of a Combination of Mifepristone with Misoprostol on Late Luteal Fertility Regulation

    Institute of Scientific and Technical Information of China (English)

    杨婕; 桂幼伦; 郑娥香; 贺昌海

    2002-01-01

    Objective To investigate the efficacy, safety and acceptability of mifepristone com-bined with misoprostol used for late luteal fertility regulationtreatment cycles in total. Subjects were planned to receive treatment with 25 mg ofmifepristone, Q12 h × 4 orally for five days prior to expected menstruation followedby 400 μg of misoprostol 48 h later for up to six cycles.Results There were 13 pregnancies in the 267 treatment cycles and among them com-plete abortion and continuing pregnancy occurred in 7 and 6 cycles respectively. So theoverall pregnancy rate was 4. 87% (13/267) and the rate of continuing pregnancywas 2. 25% (6/267), while the failure rate per pregnant cycle was 46. 15% (6/13).In treatment cycles the vaginal bleeding patterns changed insignificantly as comparedwith those in control cycles.Conclusion The efficacy, compliance and acceptability of the regimen should befurther improved when it was administered for late luteal fertility regulation.

  12. Flower synchrony, growth and yield enhancement of small type bitter gourd (Momordica charantia L.) through plant growth regulators and NPK fertilization.

    Science.gov (United States)

    Mia, Baset M A; Islam, Md Serajul; Miah, Md Yunus; Das, M R; Khan, H I

    2014-02-01

    Assessment of growth regulator and NPK fertilization effects are important tools for flower stimulation and yield improvement in cucurbits. This investigation demonstrates the comparative male-female flower induction and fruit yield of small sized bitter gourd treated with NPK fertilizers and plant growth regulators. Namely, two experiments having three replicates were conducted in a Randomized Complete Block Design (RCBD) with NPK fertilization and plant growth regulators-GA3, NAA and Ethophon application on small sized bitter gourd-genotype BG5 at the research field of the Bangabandhu Sheikh Mujibur Rahman Agricultural University (BSMRAU). In experiment 1, different doses of NPK fertilizers comprised of 10 treatments and in that of experiment 2, different levels of plant growth regulators indicated 10 treatments. The results indicated that application of different doses of NPK fertilizer and plant growth regulators significantly (< or = 0.05) influenced over the flower initiation and fruit setting. The application of N90-P45-K60 fertilizer along with Ethophon spraying resulted in the better yield of small sized bitter gourd.

  13. 78 FR 71476 - Authority for Voluntary Withholding on Other Payments

    Science.gov (United States)

    2013-11-29

    ...)(3) authorizes the Secretary to provide regulations for withholding from (A) remuneration for... AGENCY: Internal Revenue Service (IRS), Treasury. ACTION: Temporary regulations. SUMMARY: This document contains temporary regulations under the Internal Revenue Code (Code) relating to voluntary withholding...

  14. Germ-Cell-Specific Inflammasome Component NLRP14 Negatively Regulates Cytosolic Nucleic Acid Sensing to Promote Fertilization.

    Science.gov (United States)

    Abe, Takayuki; Lee, Albert; Sitharam, Ramaswami; Kesner, Jordan; Rabadan, Raul; Shapira, Sagi D

    2017-04-18

    Cytosolic sensing of nucleic acids initiates tightly regulated programs to limit infection. Oocyte fertilization represents a scenario wherein inappropriate responses to exogenous yet non-pathogen-derived nucleic acids would have negative consequences. We hypothesized that germ cells express negative regulators of nucleic acid sensing (NAS) in steady state and applied an integrated data-mining and functional genomics approach to identify a rheostat of DNA and RNA sensing-the inflammasome component NLRP14. We demonstrated that NLRP14 interacted physically with the nucleic acid sensing pathway and targeted TBK1 (TANK binding kinase 1) for ubiquitination and degradation. We further mapped domains in NLRP14 and TBK1 that mediated the inhibitory function. Finally, we identified a human nonsense germline variant associated with male sterility that results in loss of NLRP14 function and hyper-responsiveness to nucleic acids. The discovery points to a mechanism of nucleic acid sensing regulation that may be of particular importance in fertilization. Copyright © 2017 Elsevier Inc. All rights reserved.

  15. [The Influence of the Functioning of Brain Regulatory Systems onto the Voluntary Regulation of Cognitive Performance in Children. Report 2. Neuropsychological and Electrophysiological Assessment of Brain Regulatory Functions in Children Aged 10-12 with Learning Difficulties].

    Science.gov (United States)

    Semenova, O A; Machinskaya, R I

    2015-01-01

    A total number of 172 children aged 10-12 were electrophysiologically and neuropsychologically assessed in order to analyze the influence of the functioning of brain regulatory systems onto the voluntary regulation of cognitive performance during the preteen years. EEG patterns associated with the nonoptimal functioning of brain regulatory systems, particularly fronto-thalamic, limbic and fronto-striatal structures were significantly more often observed in children with learning and behavioral difficulties, as compared to the control group. Neuropsychological assessment showed that the nonoptimal functioning of different brain regulatory systems specifically affect the voluntary regulation of cognitive performance. Children with EEG patterns of fronto-thalamic nonoptimal functioning demonstrated poor voluntary regulation such as impulsiveness and difficulties in continuing the same algorithms. Children with EEG patterns of limbic nonoptimal functioning showed a less pronounced executive dysfunction manifested only in poor switching between program units within a task. Children with EEG patterns of fronto-striatal nonoptimal functioning struggled with such executive dysfunctions as motor and tactile perseverations and emotional-motivational deviations such as poor motivation and communicative skills.

  16. Effects of cereal breakfasts on postprandial glucose, appetite regulation and voluntary energy intake at a subsequent standardized lunch; focusing on rye products

    Directory of Open Access Journals (Sweden)

    Björck Inger ME

    2011-01-01

    Full Text Available Abstract Background Rye products have been demonstrated to lower the acute insulin demand, induce a low and prolonged blood glucose response (high Glycemic Profile, GP and reduce subclinical inflammation. These products may therefore contribute to a lowered risk of obesity, type 2 diabetes and cardio vascular disease. The objective of the present paper was to evaluate the mechanism for a reduced postprandial insulin demand with rye products, and to explore possible appetite regulating properties. Methods 10 healthy subjects were served breakfast meals (50 g of available starch with endosperm- or whole grain rye breads, with and without lactic acid, boiled whole grain rye- (RK or wheat (WK kernels, or white wheat bread reference (WWB in random order in a cross-over design. Plasma concentrations of glucose, ghrelin, serum insulin, free fatty acids, adiponectin, breath hydrogen excretion (H2, and subjective satiety was evaluated during the postprandial phase. 270 min after the breakfast, an ad lib lunch buffet was served and the voluntary energy intake (EI was registered. Results All rye products and WK induced lower insulinemic indices (II than WWB. A lower incremental insulin peak following breakfast correlated with a lower EI at lunch (r = 0.38. A low II was related to improved satiety in the early postprandial phase (fullness AUC 0-60 min, r = -0.36. RK induced a higher GP compared to WWB and WK. A higher GP was related to a lowered desire to eat before lunch (AUC 210-270 and to a lower concentration of ghrelin in the late postprandial phase after breakfast (270 min, r = -0.29 and -0.29, which in turn was related to a lower voluntary EI (r = 0.43 and 0.33. The RK breakfast improved satiety in the early postprandial phase (0-60 min compared to WWB, and induced a lower EI at lunch (-16%. A high content of indigestible carbohydrates in the breakfast products was related to improved satiety (0-60 min, r = 0.68 for fullness, and a higher breath H2

  17. Fertilization competence of the egg-coating envelope is regulated by direct interaction of dicalcin and gp41, the Xenopus laevis ZP3.

    Science.gov (United States)

    Miwa, Naofumi; Ogawa, Motoyuki; Hanaue, Mayu; Takamatsu, Ken

    2015-08-05

    Fertilization begins with species-restricted interaction of sperm and the egg-coating envelope, which includes a three-dimensional meshwork of filaments composed of glycoproteins (called ZP proteins). Growing evidence has unveiled the molecular nature of ZP proteins; however, the structural property conferring fertilization competence to the egg-coating envelope remains unknown. Here, we show the molecular mechanism that mediates direct interaction between dicalcin, a novel fertilization-suppressive ZP protein-associated protein, and gp41, a Xenopus laevis ortholog of mammalian ZP3, and subsequently demonstrate the structural basis of the envelope for fertilization competence. The interactive regions between dicalcin and gp41 comprised five and nine amino acid residues within dicalcin and twenty-three within gp41 [corrected]. Synthetic peptides corresponding to these regions dramatically affected fertilization: treatment with dicalcin- or gp41-derived peptides decreased or increased fertilization rates, respectively. Prior application of these peptides caused distinct alterations in the in vivo lectin-staining pattern of the envelope as well. Transmission electron microscopy analysis revealed that the dicalcin-derived peptide induced the formation of a well-organized meshwork, whereas the gp41-derived peptide caused the formation of a significantly disorganized meshwork. These findings indicated that the fertilization competence of the egg-coating envelope is crucially regulated by the direct interaction between dicalcin and gp41.

  18. Physiological Basis of Photosynthetic Function and Senescence of Rice Leaves as Regulated by Controlled-Release Nitrogen Fertilizer

    Institute of Scientific and Technical Information of China (English)

    NIE Jun; ZHENG Sheng-xian; DAI Pin-gan; XIAO Jian; YI Guo-ying

    2005-01-01

    The physiological mechanism of photosynthetic function and senescence of rice leaves was studied by using early rice variety Baliangyou 100 and late rice variety Weiyou 46, treated with controlled-release nitrogen fertilizer (CRNF), urea and no nitrogen fertilizer. CRNF showed obvious effects on delaying the senescence and prolonging photosynthetic function duration of rice leaves. Compared with urea, CRNF could significantly increase the chlorophyll content of functional leaves in both early and late rice varieties, and this difference between the treatments became larger as rice growth progressed; CRNF increased the activities of active oxygen scavenging enzymes super oxide dismutase (SOD) and peroxidase (POD), and decreased the accumulation amount of malondialdehyde (MDA) in functional leaves during leaf aging; Photosynthetic rate of functional leaves in CRNF treatment was significantly higher than that in urea treatment. The result also indicated that CRNF could effectively regulate the contents of indole-3-acetic acid (IAA) and abscisic acid (ABA) in functional leaves; IAA content was higher and ABA content was lower in CRNF treatment than those in urea treatment. Therefore, application of CRNF could increase the rice yield significantly due to these physiological changes in the functional leaves.

  19. Adaptive Regulation of Testis Gene Expression and Control of Male Fertility by the Drosophila Harpin RNA Pathway

    Science.gov (United States)

    Wen, Jiayu; Duan, Hong; Bejarano, Fernando; Okamura, Katsutomo; Fabian, Lacramioara; Brill, Julie A.; Bortolamiol-Becet, Diane; Martin, Raquel; Ruby, J. Graham; Lai, Eric C.

    2014-01-01

    SUMMARY Although endogenous siRNAs (endo-siRNAs) have been described in many species, still little is known about their endogenous utility. Here, we show that Drosophila hairpin RNAs (hpRNAs) generate an endo-siRNA class with predominant expression in testes. Although hpRNAs are universally recently evolved, we identify highly complementary protein-coding targets for all hpRNAs. Importantly, we find broad evidence for evolutionary divergences that preferentially maintain compensatory pairing between hpRNAs and targets, serving as first evidence for adaptive selection for siRNA-mediated target regulation in metazoans. We demonstrate organismal impact of hpRNA activity, since knockout of hpRNA1 derepresses its target ATP synthase-β in testes and compromises spermatogenesis and male fertility. Moreover, we reveal surprising male-specific impact of RNAi factors on germ cell development and fertility, consistent with testis-directed function of the hpRNA pathway. Finally, the collected hpRNA loci chronicle an evolutionary timeline that reflects their origins from prospective target genes, mirroring a strategy described for plant miRNAs. PMID:25544562

  20. Proteomics of spermatogenesis: from protein lists to understanding the regulation of male fertility and infertility

    Institute of Scientific and Technical Information of China (English)

    Xiaoyan Huang; Jiahao Sha

    2011-01-01

    Proteomic technologies have undergone significant development in recent years, which has led to extensive advances in protein research. Currently, proteomic approaches have been applied to many scientific areas, including basic research, various disease and malignant tumour diagnostics, biomarker discovery and other therapeutic applications. In addition, proteomics-driven research articles examining reproductive biology and medicine are becoming increasingly common. The key challenge for this field is to move from lists of identified proteins to obtaining biological information regarding protein function. The present article reviews the available scientific literature related to spermatogenesis. In addition, this study uses two-dimensional electrophoresis mass spectrometry (2DE-MS) and liquid chromatography (LC)-MS to construct a series of proteome profiles describing spermatogenesis. This large-scale identification of proteins provides a rich resource for elucidating the mechanisms underlying male fertility and infertility.

  1. Modified super-long down-regulation protocol improves fertilization and pregnancy in patients with poor ovarian responses

    Institute of Scientific and Technical Information of China (English)

    ZHANG Hui-juan; SONG Xue-ru; L(U) Rui; XUE Feng-xia

    2012-01-01

    Background The successful end-point of in vitro fertilization (IVF) treatment is for a woman to give live birth.This outcome is based on various factors including adequate number of retrieved eggs.Failure to recruit adequate follicles,from which the eggs are retrieved,is called a "poor response".How to improve the clinical pregnancy rates of poor responders was one of the tough problems for IVF.Methods The study involved 51 patients who responded poorly to high dose gonadotropin treatment in their previous cycles at our reproductive center,between April 2010 and February 2012.The previous cycle (group A) received routine long protocol; the subsequent cycle (group B) received modified super-long down-regulation protocol.The primary outcome of the study was the number of oocytes fertilized.The increase in the pregnancy rate was the secondary outcome.Differences between the groups were assessed by using Student's t test and x2 test where appropriate.Results The patients' average age was (36.64±3.85) years.The mean duration of ovarian stimulation cycles of the group A patients was longer than those of the group B patients.The total dose of follicle-stimulating hormone (FSH) was significantly lower in the subsequent cycle.The peak value of serum estradiol on human chorionic gonadotrophin (hCG) day was lower in group A as compared with group B.The number of metaphase Ⅱ oocytes recovered was significantly higher in group B.The cleavage rate in group A was significantly lower than in group B,49 patients in group B reached embryo transfer stage,while 46 patients in group A reached this stage.Patients in group B received significantly more embryos per transfer as compared with group A.More pregnancies and more clinical pregnancies with fetal heart activity were achieved in group B.Conclusions This comparative trial shows that poor responder women undergoing repeated assisted reproduction treatment using modified super-long down-regulation protocol achieve more oocytes

  2. A young Drosophila duplicate gene plays essential roles in spermatogenesis by regulating several Y-linked male fertility genes.

    Directory of Open Access Journals (Sweden)

    Yun Ding

    Full Text Available Gene duplication is supposed to be the major source for genetic innovations. However, how a new duplicate gene acquires functions by integrating into a pathway and results in adaptively important phenotypes has remained largely unknown. Here, we investigated the biological roles and the underlying molecular mechanism of the young kep1 gene family in the Drosophila melanogaster species subgroup to understand the origin and evolution of new genes with new functions. Sequence and expression analysis demonstrates that one of the new duplicates, nsr (novel spermatogenesis regulator, exhibits positive selection signals and novel subcellular localization pattern. Targeted mutagenesis and whole-transcriptome sequencing analysis provide evidence that nsr is required for male reproduction associated with sperm individualization, coiling, and structural integrity of the sperm axoneme via regulation of several Y chromosome fertility genes post-transcriptionally. The absence of nsr-like expression pattern and the presence of the corresponding cis-regulatory elements of the parental gene kep1 in the pre-duplication species Drosophila yakuba indicate that kep1 might not be ancestrally required for male functions and that nsr possibly has experienced the neofunctionalization process, facilitated by changes of trans-regulatory repertories. These findings not only present a comprehensive picture about the evolution of a new duplicate gene but also show that recently originated duplicate genes can acquire multiple biological roles and establish novel functional pathways by regulating essential genes.

  3. NARROW AND ROLLED LEAF 2 regulates leaf shape, male fertility, and seed size in rice

    Institute of Scientific and Technical Information of China (English)

    Shuangshuang Zhao; Lei Zhao; Fengxia Liu; Yongzhen Wu; Zuofeng Zhu; Chuanqing Sun; Lubin Tan

    2016-01-01

    Grain yield in rice (Oryza sativa L.) is closely related to leaf and flower development. Coordinative regulation of leaf, pollen, and seed development in rice as a critical biological and agricultural question should be addressed. Here we identified two allelic rice mutants with narrow and semi-rolled leaves, named narrow and rolled leaf 2-1 (nrl2-1) and nrl2-2. Map-based molecular cloning revealed that NRL2 encodes a novel protein with unknown biochemical function. The mutation of NRL2 caused pleiotropic effects, including a reduction in the number of longitudinal veins, defective abaxial sclerenchymatous cell differentiation, abnormal tape-tum degeneration and microspore development, and the formation of more slender seeds compared with the wild type (WT). The NRL2 protein interacted with Rolling-leaf (RL14), causing the leaves of the nrl2 mutants to have a higher cellulose content and lower lignin content than the WT, which may have been related to sclerenchymatous cell differentia-tion and tapetum degeneration. Thus, this gene is an essential developmental regulator controlling fundamental cellular and developmental processes, serving as a potential breeding target for high-yielding rice cultivars.

  4. Rethinking voluntary euthanasia.

    Science.gov (United States)

    Stoyles, Byron J; Costreie, Sorin

    2013-12-01

    Our goal in this article is to explicate the way, and the extent to which, euthanasia can be voluntary from both the perspective of the patient and the perspective of the health care providers involved in the patient's care. More significantly, we aim to challenge the way in which those engaged in ongoing philosophical debates regarding the morality of euthanasia draw distinctions between voluntary, involuntary, and nonvoluntary euthanasia on the grounds that drawing the distinctions in the traditional manner (1) fails to reflect what is important from the patient's perspective and (2) fails to reflect the significance of health care providers' interests, including their autonomy and integrity.

  5. Voluntary Public Unemployment Insurance

    DEFF Research Database (Denmark)

    O. Parsons, Donald; Tranæs, Torben; Bie Lilleør, Helene

    Denmark has drawn much attention for its active labor market policies, but is almost unique in offering a voluntary public unemployment insurance program requiring a significant premium payment. A safety net program – a less generous, means-tested social assistance plan – completes the system...

  6. Nitrogen Fertilizer and Growth Regulator Impacts on Tuber Deformity, Rot, and Yield for Russet Potatoes

    Directory of Open Access Journals (Sweden)

    Mark S. Reiter

    2012-01-01

    Full Text Available Potatoes (Solanum tuberosum are an important high-value commodity for producers in the Mid-Atlantic Region. Current production recommendations were based on white potatoes, and practices for Russet potatoes have not been researched in this region. The objective of this study was to test impacts of N rate (0, 67, 134, 201, and 268 kg N ha−1, N application timing (100% applied with planter, 2-way split (30% with planter and 70% band applied approximately 30 days after planting at dragoff, and three-way split (30% with planter, 50% band applied prior to drag-off, and 20% band applied at first sight of bloom, and additions of the growth regulator maleic hydrazide (MH-30. We tested “Goldrush” and “Norkotah” Russet potato varieties on marketability, total yield, tuber deformity, and tuber soft rot incidence for sandy loam soils in the Mid-Atlantic. Overall, year variations were significant with substantial rots (up to 86.5% occurring in year 3. Maleic hydrazide and N application timing had little consistent effect on any tested parameter. Nitrogen rate and variety factors had the greatest impacts on deformity, tuber rots, and yields for Russet potatoes in the Mid-Atlantic Region with 134 kg N ha−1 producing the highest total yields in 2009 and 2010. If tuber rots can be controlled, both “Goldrush” and “Norkotah” are acceptable varieties under the Mid-Atlantic production practices.

  7. 5 CFR 630.1014 - Movement between voluntary leave bank programs.

    Science.gov (United States)

    2010-01-01

    ... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false Movement between voluntary leave bank programs. 630.1014 Section 630.1014 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS ABSENCE AND LEAVE Voluntary Leave Bank Program § 630.1014 Movement between voluntary leave...

  8. 5 CFR 630.1016 - Termination of a voluntary leave bank program.

    Science.gov (United States)

    2010-01-01

    ... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false Termination of a voluntary leave bank program. 630.1016 Section 630.1016 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS ABSENCE AND LEAVE Voluntary Leave Bank Program § 630.1016 Termination of a voluntary leave...

  9. 78 FR 71542 - Authority for Voluntary Withholding on Other Payments

    Science.gov (United States)

    2013-11-29

    ...)(3) authorizes the Secretary to provide regulations for withholding from (A) remuneration for... proposed rulemaking by cross reference to temporary regulations. SUMMARY: This document contains proposed regulations under the Internal Revenue Code (Code) relating to voluntary withholding agreements. In the Rules...

  10. Fertility incentives and disincentives.

    Science.gov (United States)

    Financioglu, N

    1984-06-01

    Some 40 countries use some form of incentives and disincentives in support of population policies, about half with the aim of reducing fertility and half with the aim of increasing it. These schemes range from limitations on tax and family allowances or maternity benefits after a given family size has been reached to payments to acceptors of fertility control methods. Some schemes aim to eliminate or reduce the cost and inconvenience people may face in achieving their fertility preferences, whereas others contain an element of deterrence. It is difficult to isolate and measure the impact of incentives on fertility from the effects of other factors such as family planning service availability or modernization. Studies in pronatalist countries suggest that incentive schemes produce short-term fertility increases without a change in average family size. Monetary incentives must be constantly increased to keep pace with inflation, placing a heavy burden on government budgets. Administrative capacity to operate the scheme is critical in terms of both manpower and efficient systems for record keeping, monitoring, and close supervision to prevent abuse. There is also considerable debate on the moral and ethical implications of incentives and disincentives as policy tools. Incentives offered for the acceptance of a particular fertility control method potentially contravene the principle of voluntary and informed consent. In addition, the relative value of the reward is greater for those in the lower income groups. The discriminatory nature of certain types of incentives and disincentives is illustrated by measures introduced in Singapore that give highest priority in school enrollment to the children of highly educated mothers with 2-3 children. This ruling is expected to further intensify the controversy surrounding incentive and disincentive schemes.

  11. Regulation of Mitochondrial Genome Inheritance by Autophagy and Ubiquitin-Proteasome System: Implications for Health, Fitness, and Fertility

    Directory of Open Access Journals (Sweden)

    Won-Hee Song

    2014-01-01

    Full Text Available Mitochondria, the energy-generating organelles, play a role in numerous cellular functions including adenosine triphosphate (ATP production, cellular homeostasis, and apoptosis. Maternal inheritance of mitochondria and mitochondrial DNA (mtDNA is universally observed in humans and most animals. In general, high levels of mitochondrial heteroplasmy might contribute to a detrimental effect on fitness and disease resistance. Therefore, a disposal of the sperm-derived mitochondria inside fertilized oocytes assures normal preimplantation embryo development. Here we summarize the current research and knowledge concerning the role of autophagic pathway and ubiquitin-proteasome-dependent proteolysis in sperm mitophagy in mammals, including humans. Current data indicate that sperm mitophagy inside the fertilized oocyte could occur along multiple degradation routes converging on autophagic clearance of paternal mitochondria. The influence of assisted reproductive therapies (ART such as intracytoplasmic sperm injection (ICSI, mitochondrial replacement (MR, and assisted fertilization of oocytes from patients of advanced reproductive age on mitochondrial function, inheritance, and fitness and for the development and health of ART babies will be of particular interest to clinical audiences. Altogether, the study of sperm mitophagy after fertilization has implications in the timing of evolution and developmental and reproductive biology and in human health, fitness, and management of mitochondrial disease.

  12. Regulation of mitochondrial genome inheritance by autophagy and ubiquitin-proteasome system: implications for health, fitness, and fertility.

    Science.gov (United States)

    Song, Won-Hee; Ballard, John William Oman; Yi, Young-Joo; Sutovsky, Peter

    2014-01-01

    Mitochondria, the energy-generating organelles, play a role in numerous cellular functions including adenosine triphosphate (ATP) production, cellular homeostasis, and apoptosis. Maternal inheritance of mitochondria and mitochondrial DNA (mtDNA) is universally observed in humans and most animals. In general, high levels of mitochondrial heteroplasmy might contribute to a detrimental effect on fitness and disease resistance. Therefore, a disposal of the sperm-derived mitochondria inside fertilized oocytes assures normal preimplantation embryo development. Here we summarize the current research and knowledge concerning the role of autophagic pathway and ubiquitin-proteasome-dependent proteolysis in sperm mitophagy in mammals, including humans. Current data indicate that sperm mitophagy inside the fertilized oocyte could occur along multiple degradation routes converging on autophagic clearance of paternal mitochondria. The influence of assisted reproductive therapies (ART) such as intracytoplasmic sperm injection (ICSI), mitochondrial replacement (MR), and assisted fertilization of oocytes from patients of advanced reproductive age on mitochondrial function, inheritance, and fitness and for the development and health of ART babies will be of particular interest to clinical audiences. Altogether, the study of sperm mitophagy after fertilization has implications in the timing of evolution and developmental and reproductive biology and in human health, fitness, and management of mitochondrial disease.

  13. Fertility Awareness

    Science.gov (United States)

    ... I Help Someone Who's Being Bullied? Volunteering Fertility Awareness KidsHealth > For Teens > Fertility Awareness Print A A A What's in this article? ... español Monitoreo de fertilidad What Is It? Fertility awareness is a way to prevent pregnancy by not ...

  14. Aurora-A is a critical regulator of microtubule assembly and nuclear activity in mouse oocytes, fertilized eggs, and early embryos.

    Science.gov (United States)

    Yao, Li-Juan; Zhong, Zhi-Sheng; Zhang, Li-Sheng; Chen, Da-Yuan; Schatten, Heide; Sun, Qing-Yuan

    2004-05-01

    Aurora-A is a serine/threonine protein kinase that plays a role in cell-cycle regulation. The activity of this kinase has been shown to be required for regulating multiple stages of mitotic progression in somatic cells. In this study, the changes in aurora-;A expression were revealed in mouse oocytes using Western blotting. The subcellular localization of aurora-A during oocyte meiotic maturation, fertilization, and early cleavages as well as after antibody microinjection or microtubule assembly perturbance was studied with confocal microscopy. The quantity of aurora-A protein was high in the germinal vesicle (GV) and metaphase II (MII) oocytes and remained stable during other meiotic maturation stages. Aurora-A concentrated in the GV before meiosis resumption, in the pronuclei of fertilized eggs, and in the nuclei of early embryo blastomeres. Aurora-A was localized to the spindle poles of the meiotic spindle from the metaphase I (MI) stage to metaphase II stage. During early embryo development, aurora-A was found in association with the mitotic spindle poles. Aurora-A was not found in the spindle region when colchicine or staurosporine was used to inhibit microtubule organization, while it accumulated as several dots in the cytoplasm after taxol treatment. Aurora-A antibody microinjection decreased the rate of germinal vesicle breakdown (GVBD) and distorted MI spindle organization. Our results indicate that aurora-A is a critical regulator of cell-cycle progression and microtubule organization during mouse oocyte meiotic maturation, fertilization, and early embryo cleavage.

  15. Voluntary Simplicity: A Lifestyle Option.

    Science.gov (United States)

    Pestle, Ruth E.

    This guide provides practical ideas for incorporating the concept of voluntary simplicity into home economics classes. Discussed in the first chapter are the need to study voluntary simplicity, its potential contributions to home economics, and techniques and a questionnaire for measuring student attitudes toward the concept. The remaining…

  16. Operant Variability and Voluntary Action

    Science.gov (United States)

    Neuringer, Allen; Jensen, Greg

    2010-01-01

    A behavior-based theory identified 2 characteristics of voluntary acts. The first, extensively explored in operant-conditioning experiments, is that voluntary responses produce the reinforcers that control them. This bidirectional relationship--in which reinforcer depends on response and response on reinforcer--demonstrates the functional nature…

  17. Toward voluntary parenthood.

    Science.gov (United States)

    Scarr, S

    2000-06-01

    David Lykken's proposal to license married parents for child rearing, and to deny the same opportunity to single and inept parents, springs from his deep concern for millions of youngsters cruelly subjected to abusive and neglectful rearing circumstances. Children from such inadequate homes grow up to have high rates of school failure, criminality, and drug addiction. The problem is clear, but Lykken's remedies of mandated marriage and parental licensure are unacceptable in U.S. society, where our reproductive rights are fortunately protected by our Constitution. As a devoted proponent of reproductive rights, I propose a legally and morally acceptable proposal to the same end. Increasing women's effective control of reproduction and moving toward entirely voluntary parenthood will accomplish the same goals without compromising our civil liberties.

  18. Regulation of Mitochondrial Genome Inheritance by Autophagy and Ubiquitin-Proteasome System: Implications for Health, Fitness, and Fertility

    OpenAIRE

    Won-Hee Song; John William Oman Ballard; Young-Joo Yi; Peter Sutovsky

    2014-01-01

    Mitochondria, the energy-generating organelles, play a role in numerous cellular functions including adenosine triphosphate (ATP) production, cellular homeostasis, and apoptosis. Maternal inheritance of mitochondria and mitochondrial DNA (mtDNA) is universally observed in humans and most animals. In general, high levels of mitochondrial heteroplasmy might contribute to a detrimental effect on fitness and disease resistance. Therefore, a disposal of the sperm-derived mitochondria inside fertil...

  19. Explorations of mechanisms regulating ectomycorrhizal colonization of boron-fertilized pine: Quarterly report, 8/20/86-3/31/87

    Energy Technology Data Exchange (ETDEWEB)

    Garrett, H.E.

    1987-01-01

    Shortleaf pine seedings were inoculated with Pisolithus tinctorius had extensive ectomycorrhizal development throughout the root system. Fructose, glucose, sucrose, pinitol, and myoinositol were extracted and quantitated from roots. Sucrose accounted for about one-third of the total sugar content. In general, mycorrhizal roots contained significantly higher concentrations of total carbohydrates than nonmycorrhizal roots. Amont individual sugars identified, the concentrations of pinitol, fructose, glucose and sucrose were especially affected by ectomycorrhizal development and/or boron(B) fertilization. Mycorrhizal root systems contained greater concentrations of fructose than nonmycorrhizal root systems irrespective of method of B fertilization. Similarly, pinitol, glucose, and sucrose were typically more prevalent in mycorrhizal root systems although exceptions were found. Within mycorrhizal treatments, significant interactions were observed between method of B application and the concentration of individual sugars. In mycorrhizal plants, foliar + soil and soil application treatments yielded the greatest increases in individual sugars. Individual sugars in nonmycorrhizal roots were affected less by B fertilization than in mycorrhizal roots. Significant increases were, however, observed in fructose with either foliar + soil or soil-applied B, in glucose with foliar-applied B, and in sucrose with soil-applied B. 23 refs., 1 fig., 1 tab.

  20. APPLICATION OF FREQUENCY SPEED REGULATION TO FERTILIZER PRODUCTION PLANT%变频调速技术在化肥生产装置中的应用

    Institute of Scientific and Technical Information of China (English)

    聂志华

    2012-01-01

    To analyze technically the speed regulation,start-up and energy saving of frequency converter and introduce the actual application example of the technology of frequency speed regulation in fertilizer production plant;aiming at the common problems in the application of such technology the resolutions proposed.%对变频器的调速、启动、节能三个方面进行技术分析,介绍变频调速技术在化肥生产装置中的应用实例,针对变频调速技术应用中的常见问题,提出解决措施。

  1. C13C4.5/Spinster, an evolutionarily conserved protein that regulates fertility in C. elegans through a lysosome-mediated lipid metabolism process.

    Science.gov (United States)

    Han, Mei; Chang, Hao; Zhang, Peng; Chen, Tao; Zhao, Yanhua; Zhang, Yongdeng; Liu, Pingsheng; Xu, Tao; Xu, Pingyong

    2013-05-01

    Lipid droplets, which are conserved across almost all species, are cytoplasmic organelles used to store neutral lipids. Identification of lipid droplet regulators will be conducive to resolving obesity and other fat-associated diseases. In this paper, we selected 11 candidates that might be associated with lipid metabolism in Caenorhabditis elegans. Using a BODIPY 493/503-based flow cytometry screen, 6 negative and 3 positive regulators of fat content were identified. We selected one negative regulator of lipid content, C13C4.5, for future study. C13C4.5 was mainly expressed in the worm intestine. We found that this gene was important for maintaining the metabolism of lipid droplets. Biochemical results revealed that 50% of triacylglycerol (TAG) was lost in C13C4.5 knockout worms. Stimulated Raman scattering (SRS) signals in C13C4.5 mutants showed only 49.6% of the fat content in the proximal intestinal region and 86.3% in the distal intestinal region compared with wild type animals. The mean values of lipid droplet size and intensity in C13C4.5 knockout animals were found to be significantly decreased compared with those in wild type worms. The LMP-1-labeled membrane structures in worm intestines were also enlarged in C13C4.5 mutant animals. Finally, fertility defects were found in C13C4.5(ok2087) mutants. Taken together, these results indicate that C13C4.5 may regulate the fertility of C. elegans by changing the size and fat content of lipid droplets by interfering with lysosomal morphology and function.

  2. Natural fertility in the Philippines.

    Science.gov (United States)

    Aquino, E G

    1982-01-01

    The hypothesis that modernization trends in the Philippines led to an increase in fecundity and natural fertility between 1953-1972 was tested, using data from the 1973 National Demographic Survey. More specifically, it was hypothesized that increases in education, income levels, urbanization, female labor force participation, and other factors exerted a positive influence on the population's health and nutritional status and increased the risk of pregnancy by diminishing the strength of sexual taboos and by decreasing the incidence of breastfeeding. These changes, in turn, had a positive impact on natural fertility. Natural fertility was defined as marital fertility in the absence of specific efforts to control fertility. The use of natural fertility instead of fecundity allowed for the influence of behavioral patterns, such as breastfeeding and sexual taboos, on fertility. Period analysis of age specific marital fertility rates for each 5 year period between 1953-72 and cohort analysis of age specific marital fertility rates for the birth cohorts, aged 55-59, 50-54, 45-49, 40-44, and 35-39 in 1973 were undertaken. The effect of fertility control was determined by using an index derived from an equation provided by Coale and Trussell. Findings of both the period and cohort analysis supported the hypothesis. Period analysis revealed that natural fertility increased between 1953-57 and 1969-72 by 10% and that the greatest increase occurred during the 1950s when Philippine society experienced major modernization changes. The increases in natural fertility were accompanied by corresponding increases in fertility regulation in each time period. These trends tended to cancel each other out and resulted in a relatively stable total marital fertility rate throughout the time period. Cohort analysis revealed that only the total marital fertility rate of the youngest cohort was influenced by fertility regulation. The level of natural fertility for all cohorts as a group

  3. Analyzing voluntary medical incident reports.

    Science.gov (United States)

    Gong, Yang; Richardson, James; Zhijian, Luan; Alafaireet, Patricia; Yoo, Illhoi

    2008-11-06

    Voluntary medical incident reports lacking consistency and accuracy impede the ultimate use of the reports for patient safety research. To improve this, two coders examined harm score usage in a voluntary medical incident reporting system where the harm scores were selected from a predefined list by different reporters. The two coders inter-rater agreement percent was 82%. The major categories and reviewed harm score jointly demonstrate that this process is critical and necessary in preparing the voluntary reports for further content and semantics analysis.

  4. Management, regulation and environmental impacts of nitrogen fertilization in northwestern Europe under the Nitrates Directive; a benchmark study

    Science.gov (United States)

    van Grinsven, H. J. M.; ten Berge, H. F. M.; Dalgaard, T.; Fraters, B.; Durand, P.; Hart, A.; Hofman, G.; Jacobsen, B. H.; Lalor, S. T. J.; Lesschen, J. P.; Osterburg, B.; Richards, K. G.; Techen, A.-K.; Vertès, F.; Webb, J.; Willems, W. J.

    2012-12-01

    Implementation of the Nitrates Directive (NiD) and its environmental impacts were compared for member states in the northwest of the European Union (Ireland, United Kingdom, Denmark, the Netherlands, Belgium, Northern France and Germany). The main sources of data were national reports for the third reporting period for the NiD (2004-2007) and results of the MITERRA-EUROPE model. Implementation of the NiD in the considered member states is fairly comparable regarding restrictions for where and when to apply fertilizer and manure, but very different regarding application limits for N fertilization. Issues of concern and improvement of the implementation of the NiD are accounting for the fertilizer value of nitrogen in manure, and relating application limits for total nitrogen (N) to potential crop yield and N removal. The most significant environmental effect of the implementation of the NiD since 1995 is a major contribution to the decrease of the soil N balance (N surplus), particularly in Belgium, Denmark, Ireland, the Netherlands and the United Kingdom. This decrease is accompanied by a modest decrease of nitrate concentrations since 2000 in fresh surface waters in most countries. This decrease is less prominent for groundwater in view of delayed response of nitrate in deep aquifers. In spite of improved fertilization practices, the southeast of the Netherlands, the Flemish Region and Brittany remain to be regions of major concern in view of a combination of a high nitrogen surplus, high leaching fractions to groundwater and tenacious exceedance of the water quality standards. On average the gross N balance in 2008 for the seven member states in EUROSTAT and in national reports was about 20 kg N ha-1 yr-1 lower than by MITERRA. The major cause is higher estimates of N removal in national reports which can amount to more than 50 kg N ha-1 yr-1. Differences between procedures in member states to assess nitrogen balances and water quality and a lack of cross

  5. Management, regulation and environmental impacts of nitrogen fertilization in northwestern Europe under the Nitrates Directive; a benchmark study

    Directory of Open Access Journals (Sweden)

    H. J. M. van Grinsven

    2012-12-01

    Full Text Available Implementation of the Nitrates Directive (NiD and its environmental impacts were compared for member states in the northwest of the European Union (Ireland, United Kingdom, Denmark, the Netherlands, Belgium, Northern France and Germany. The main sources of data were national reports for the third reporting period for the NiD (2004–2007 and results of the MITERRA-EUROPE model. Implementation of the NiD in the considered member states is fairly comparable regarding restrictions for where and when to apply fertilizer and manure, but very different regarding application limits for N fertilization. Issues of concern and improvement of the implementation of the NiD are accounting for the fertilizer value of nitrogen in manure, and relating application limits for total nitrogen (N to potential crop yield and N removal. The most significant environmental effect of the implementation of the NiD since 1995 is a major contribution to the decrease of the soil N balance (N surplus, particularly in Belgium, Denmark, Ireland, the Netherlands and the United Kingdom. This decrease is accompanied by a modest decrease of nitrate concentrations since 2000 in fresh surface waters in most countries. This decrease is less prominent for groundwater in view of delayed response of nitrate in deep aquifers. In spite of improved fertilization practices, the southeast of the Netherlands, the Flemish Region and Brittany remain to be regions of major concern in view of a combination of a high nitrogen surplus, high leaching fractions to groundwater and tenacious exceedance of the water quality standards. On average the gross N balance in 2008 for the seven member states in EUROSTAT and in national reports was about 20 kg N ha−1 yr−1 lower than by MITERRA. The major cause is higher estimates of N removal in national reports which can amount to more than 50 kg N ha−1 yr−1. Differences between procedures in member states to

  6. Management, regulation and environmental impacts of nitrogen fertilization in Northwestern Europe under the Nitrates Directive; a benchmark study

    Directory of Open Access Journals (Sweden)

    H. J. M. van Grinsven

    2012-06-01

    Full Text Available Implementation of the Nitrates Directive (NiD and its environmental impacts were compared for member states in the Northwest of the European Union (Ireland, UK, Denmark, The Netherlands, Belgium, Northern France and Germany. The main sources of data were national reports for the third reporting period for the NiD (2004–2007 and results of the MITERRA-EUROPE model. Implementation of the NiD in the considered member states is fairly comparable regarding restrictions for where and when to apply fertilizer and manure, but very different regarding application limits for N fertilization. Issues of concern and improvement of the implementation of the NiD are accounting for the fertilizer value of nitrogen in manure, and relating application limits for total nitrogen (N to potential crop yield and N removal. The most significant environmental effect of the implementation of the NiD since 1995 is a major contribution to the decrease of the soil N balance (N surplus, particularly in Belgium, Denmark, Ireland, The Netherlands and the UK. This decrease is accompanied by a modest decrease of nitrate concentrations since 2000 in fresh surface waters in most countries. This decrease is less prominent for groundwater in view of delayed response of nitrate in deep aquifers. In spite of improved fertilization practices, the southeast of The Netherlands, the Flemish Region and Brittany remain to be regions of major concern in view of a combination of a high nitrogen surplus, high leaching fractions to groundwater and tenacious exceedance of the water quality standards. On average the gross N balance in 2008 for the seven member states in EUROSTAT and in national reports was about 20 kg N ha−1 lower than by MITERRA. The major cause is higher estimates of N removal in national reports which can amount to more than 50kg N ha−1. Differences between procedures in member states to assess nitrogen balances and water quality and a lack of cross

  7. The Notion of Voluntary Unemployment.

    Science.gov (United States)

    Standing, Guy

    1981-01-01

    Considers the distinction between voluntary and involuntary unemployment by analyzing six behavioral characteristics attributed to groups of workers suspected of indulging in the former, and the labor market mechanisms supposedly encouraging them. (Author/CT)

  8. Participation of epididymal cysteine-rich secretory proteins in sperm-egg fusion and their potential use for male fertility regulation

    Institute of Scientific and Technical Information of China (English)

    Debora J. Cohen; Vanina G. Da Ros; Dolores Busso; Diego A. Ellerman; Julieta A. Maldera; Nadia Goldweic; Patricia S. Cuasnicú

    2007-01-01

    Rat protein DE is an androgen-dependent cysteine-rich secretory protein (CRISP) synthesized by proximal epididymal regions. DE, also known as CRISP- 1, is localized on the equatorial segment of acrosome-reacted spermatozoa and participates in gamete fusion through binding to egg complementary sites. Immunization of rats with DE inhibits fertility and sperm fusion ability, suggesting that DE represents a good epididymal contraceptive target.Recombinant DE fragments and synthetic peptides revealed that DE binds to the egg via a 12-amino acid region of an evolutionarily conserved motif, Signature 2 (S2). The ability of other CRISP to bind to the rat egg was correlated with their S2 amino acid sequences. Although testicular protein Tpx-1 (CRISP-2) was capable of binding to rodent eggs,human epididymal AEG-related protein (ARP) and helothermine (from lizard saliva) were not. The S2 region presented only two substitutions in Tpx-1 and four in ARP and helothermine, compared with the DE S2, suggesting that this amino acid sequence was relevant for egg interaction. Studies with Tpx-1 and anti-Tpx-1 revealed the participation of this protein in gamete fusion through binding to complementary sites in the egg. In competition studies, DE reduced binding of Tpx- 1 dose-dependently, indicating that both CRISP share the egg complementary sites. That anti-DE and anti-Tpx-1 inhibit sperm-egg fusion while recognizing only the corresponding proteins, suggests functional cooperation between these homologous CRISP to ensure fertilization success. These results increase our understanding of the molecular mechanisms of gamete fusion and contribute to the development of new and safer fertility regulating methods.

  9. A plasma membrane zinc transporter from ¤Medicago truncatula¤ is up-regulated in roots by Zn fertilization, yet down-regulated by arbuscular mycorrhizal colonization

    DEFF Research Database (Denmark)

    Burleigh, S.H.; Kristensen, B.K.; Bechmann, I.E.

    2003-01-01

    , but not in leaves of M. truncatula and, in contrast to all other plant Zn transporters characterized thus far, MtZIP2 was up-regulated in roots by Zn fertilization. Expression was highest in roots exposed to a toxic level of Zn. MtZIP2 expression was also examined in the roots of M. truncatula when colonized...... by the obligate plant symbiont, arbuscular mycorrhizal (AM) fungi, since AM fungi are renowned for their ability to supply plants with mineral nutrients, including Zn. Expression was downregulated in the roots of the mycorrhizal plants and was associated with a reduced level of Zn within the host plant tissues....

  10. Voluntary agreements as instruments for international environmental policy; Frivillege avtaler som internasjonalt miljoepolitisk verkemiddel

    Energy Technology Data Exchange (ETDEWEB)

    Torvanger, Asbjoern

    1997-12-31

    According to this report, voluntary agreements have a potential as instruments for environmental policy. Such agreements can be national or international. Through an international voluntary agreement the authorities in one country may make contracts with factories in another country about emission reductions against some kind of compensation. A supranational organisation of voluntary agreements may ensure equal environmental political conditions for factories in different countries and be a useful means for the regulation of environmental problems of regional or global extent. It is most realistic to establish a supranational system of voluntary agreements in a group of countries that have already institutionalized their relations, such as the European Union. 14 refs., 1 table

  11. The challenges of adopting voluntary health, safety and environment measures for manufactured nanomaterials

    DEFF Research Database (Denmark)

    Hansen, Steffen Foss; Tickner, J.

    2007-01-01

    This article explores the use of voluntary environmental programs in the United States in the past, and applies the lessons learned from these experiences to the regulation of nanomaterials. The authors found that the key elements of any voluntary environmental program should be incentives...

  12. 5 CFR 630.1015 - Movement between voluntary leave bank and leave transfer programs.

    Science.gov (United States)

    2010-01-01

    ... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false Movement between voluntary leave bank and leave transfer programs. 630.1015 Section 630.1015 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS ABSENCE AND LEAVE Voluntary Leave Bank Program § 630.1015...

  13. 5 CFR 630.1013 - Participation in voluntary leave transfer and leave bank programs.

    Science.gov (United States)

    2010-01-01

    ... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false Participation in voluntary leave transfer and leave bank programs. 630.1013 Section 630.1013 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS ABSENCE AND LEAVE Voluntary Leave Bank Program § 630.1013...

  14. 14 CFR 234.10 - Voluntary disclosure of on-time performance codes.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 4 2010-01-01 2010-01-01 false Voluntary disclosure of on-time performance codes. 234.10 Section 234.10 Aeronautics and Space OFFICE OF THE SECRETARY, DEPARTMENT OF TRANSPORTATION (AVIATION PROCEEDINGS) ECONOMIC REGULATIONS AIRLINE SERVICE QUALITY PERFORMANCE REPORTS § 234.10 Voluntary...

  15. 78 FR 48413 - Proposed Information Collection; Comment Request; Voluntary Self-Disclosure of Violations of the...

    Science.gov (United States)

    2013-08-08

    ... Bureau of Industry and Security Proposed Information Collection; Comment Request; Voluntary Self- Disclosure of Violations of the Export Administration Regulations AGENCY: Bureau of Industry and Security... an investigation or prosecution is necessary and to reach a settlement with violators. Voluntary self...

  16. Comparing Voluntary and Mandatory Gameplay

    Directory of Open Access Journals (Sweden)

    Esther Kuindersma

    2016-09-01

    Full Text Available Gameplay is commonly considered to be a voluntary activity. Game designers generally believe that voluntary gameplay is essentially different from mandatory gameplay. Such a belief may be a challenge for serious games, as instruction is usually mandatory. The article describes the outcomes of two experiments on the impact of voluntariness on the learning effect and enjoyment of a serious game. In the first experiment freedom of choosing to play a serious game was studied, with participants who had volunteered to participate. The results suggested that, contrary to the opinion of many game designers, being required to play a serious game does not automatically take the fun out of the game. The second experiment had voluntary participants and mandatory participants, who had to participate as part of a homework assignment. The outcomes show that mandatory participants enjoyed the game as much as the voluntary participants, even if they had to play the game for a minimum required time. These studies indicate that mandatory gameplay does not reduce enjoyment and learning effect.

  17. Voluntary organisation and adult education

    Directory of Open Access Journals (Sweden)

    Konrad Elsdon

    1998-12-01

    Full Text Available The author starts by offering a definition of voluntary organisations. He then discusses their importance and role, focusing on the issue of adult education wi­ thin these organisations. He also wells upon learning and change of voluntary organisation members, making use of the results of a study he conducted together with his collaborators. One of their fin­dings has been that voluntary organisati­ons, due to their organisational targets li­ke painting, singing or caring for people in need, lead their members to learning, i.e. essentially content learning. Moreo­ver, voluntary organisations offer a fair number of opportunities for social lear­ning and change. ln spite of the fact that the respondents were mostly not aware of the outcomes of their learning and change, careful listeners conducting the interview made them understand the im­portance of the learning they had gone through. The author concludes by poin­ ting out that formal education of adults can get its inspiration in learning in voluntary organisations. On the other hand, such learning would benefit greatly from findings and methods of formal education of adults.

  18. Does prolonged pituitary down-regulation with gonadotropin-releasing hormone agonist improve the live-birth rate in in vitro fertilization treatment?

    Science.gov (United States)

    Ren, Jianzhi; Sha, Aiguo; Han, Dongmei; Li, Ping; Geng, Jie; Ma, Chaihui

    2014-07-01

    To evaluate the effects of a prolonged duration of gonadotropin-releasing hormone agonist (GnRH-a) in pituitary down-regulation for controlled ovarian hyperstimulation (COH) on the live-birth rate in nonendometriotic women undergoing in vitro fertilization and embryo transfer (IVF-ET). Retrospective cohort study. University-affiliated hospital. Normogonadotropic women undergoing IVF. Three hundred seventy-eight patients receiving a prolonged pituitary down-regulation with GnRH-a before ovarian stimulation and 422 patients receiving a GnRH-a long protocol. Live-birth rate per fresh ET. In comparison with the long protocol, the prolonged down-regulation protocol required a higher total dose of gonadotropins. A lower serum luteinizing hormone (LH) level on the starting day of gonadotropin and the day of human chorionic gonadotropin (hCG) and a fewer number of oocytes and embryos were observed in the prolonged down-regulation protocol. However, the duration of stimulation and number of high-quality embryos were comparable between the two groups. A statistically significantly higher implantation rate (50.27% vs. 39.69%), clinical pregnancy rate (64.02% vs. 56.87%) and live-birth rate per fresh transfer cycle (55.56% vs. 45.73%) were observed in the prolonged protocol. Prolonged down-regulation in a GnRH-a protocol might increase the live-birth rates in normogonadotropic women. Copyright © 2014 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.

  19. 31 CFR 800.402 - Contents of voluntary notice.

    Science.gov (United States)

    2010-07-01

    ... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false Contents of voluntary notice. 800.402 Section 800.402 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) OFFICE...; and (D) Employer identification number or other domestic tax or corporate identification number. (d...

  20. The Histone Deacetylase SIRT1 Controls Male Fertility in Mice Through Regulation of Hypothalamic-Pituitary Gonadotropin Signaling

    NARCIS (Netherlands)

    Teerds, K.J.; Kolthur-Seerharam, U.; Rooij, de D.G.

    2009-01-01

    Sirtuins (SIRTs) are class-III NAD-dependent histone deacetylases (HDACs) that regulate various physiological processes. Inactivation of SIRT1 in the mouse leads to male sterility, but the molecular mechanisms responsible for this phenotype have not been determined. Here we show that fetal testis de

  1. The Histone Deacetylase SIRT1 Controls Male Fertility in Mice Through Regulation of Hypothalamic-Pituitary Gonadotropin Signaling

    NARCIS (Netherlands)

    Teerds, K.J.; Kolthur-Seerharam, U.; Rooij, de D.G.

    2009-01-01

    Sirtuins (SIRTs) are class-III NAD-dependent histone deacetylases (HDACs) that regulate various physiological processes. Inactivation of SIRT1 in the mouse leads to male sterility, but the molecular mechanisms responsible for this phenotype have not been determined. Here we show that fetal testis

  2. The Testis-Enriched Histone Demethylase, KDM4D, Regulates Methylation of Histone H3 Lysine 9 During Spermatogenesis in the Mouse but Is Dispensable for Fertility1

    Science.gov (United States)

    Iwamori, Naoki; Zhao, Ming; Meistrich, Marvin L.; Matzuk, Martin M.

    2011-01-01

    Epigenetic modifications, and methylation of histones in particular, dynamically change during spermatogenesis. Among various methylations of histone H3, methylation of histone H3 lysine 9 (H3K9) and its regulation are essential for spermatogenesis. Trimethytransferases as well as dimethyltransferase are required for meiotic progression. In addition, didemethylase of H3K9 is also critical for spermatogenesis through transcriptional regulation of spermatid-specific genes. However, the requirement for demethylation of trimethylated H3K9 (H3K9me3) during spermatogenesis remains to be elucidated. Here, we report the targeted disruption of KDM4D, a testis-enriched tridemethylase of H3K9. Kdm4d-null mice are viable and fertile and do not show any obvious phenotype. However, H3K9me3 accumulates significantly in Kdm4d-null round spermatids, and the distribution of methylated H3K9 in germ cells is dramatically changed. Nevertheless, the progression of spermatogenesis and the number of spermatozoa are normal, likely secondary to the earlier nuclear localization of another H3K9 tridemethylase, KDM4B, in Kdm4d-null elongating spermatids. These results suggest that demethylation of H3K9me3 in round spermatids is dispensable for spermatogenesis but that possible defects in Kdm4d-null elongating spermatids could be rescued by functional redundancy of the KDM4B demethylase. PMID:21293030

  3. Methodology for classification of commercial edification and of service according to the regulation for voluntary tagging of the energy efficiency level of commercial, services and public buildings - economic evaluation of the simulated and classified models; Metodologia para classificacao de edificacao comercial e de servico conforme a regulamentacao para etiquetagem voluntaria do nivel de eficiencia energetica de edificios comerciais, de servicos e publicos - avaliacao economica dos modelos simulados e classificados

    Energy Technology Data Exchange (ETDEWEB)

    Baptista, Norma do Nascimento; Rovere, Emilio Lebre La [Universidade Federal do Rio de Janeiro (UFRJ), RJ (Brazil). Coordenacao dos Programas de Pos-Graduacao de Engenharia (COPPE). Programa de Planejamento Energetico], e-mail: normabaptista@ppe.ufrj.br, e-mail: emilio@ppe.ufrj.br

    2008-07-01

    This article presents the methodology developed for determination of energy performance and the classification in accordance with the Regulation for the Voluntary Tagging of the Efficiency Level of commercial, services and public edifications. The methodology applies to commercial and service edification, specifically for offices and schools purposes.

  4. Responses of two grass species to plant growth regulators, fertilizer N, chelated Fe, salinity and water stress

    OpenAIRE

    Nabati, Daryoosh A.

    1991-01-01

    A series of studies were initiated to investigate growth responses of Kentucky bluegrass (Poa praetensis L.) and creeping bentgrass (Agrostis palustris Huds.) to foliar applications of two plant growth regulators (PGR) and/or chelated Fe (Na Fe diethylene triamine pentaacetate). Environmental variables considered were N levels, soil moisture regimes, and saline irrigations The two materials investigated for PGR properties were a commercial product called Roots (a cold-water extract of seaw...

  5. Voluntary euthanasia: a utilitarian perspective.

    Science.gov (United States)

    Singer, Peter

    2003-10-01

    Belgium legalised voluntary euthanasia in 2002, thus ending the long isolation of the Netherlands as the only country in which doctors could openly give lethal injections to patients who have requested help in dying. Meanwhile in Oregon, in the United States, doctors may prescribe drugs for terminally ill patients, who can use them to end their life--if they are able to swallow and digest them. But despite President Bush's oft-repeated statements that his philosophy is to 'trust individuals to make the right decisions' and his opposition to 'distant bureaucracies', his administration is doing its best to prevent Oregonians acting in accordance with a law that its voters have twice ratified. The situation regarding voluntary euthanasia around the world is therefore very much in flux. This essay reviews ethical arguments regarding voluntary euthanasia and physician-assisted suicide from a utilitarian perspective. I shall begin by asking why it is normally wrong to kill an innocent person, and whether these reasons apply to aiding a person who, when rational and competent, asks to be killed or given the means to commit suicide. Then I shall consider more specific utilitarian arguments for and against permitting voluntary euthanasia.

  6. Social Cohesion and Voluntary Associations

    Science.gov (United States)

    Heuser, Brian L.

    2005-01-01

    Voluntary organizations exert great influence over how social norms and ethical codes are guided into action. As such, they have a significant impact on societal levels of social cohesion. Although social capital involves generalized trust becoming manifest as spontaneous sociability, social cohesion is determined by how that sociability is…

  7. Voluntary Incentive Early Retirement Programs.

    Science.gov (United States)

    Research Dialogues, 1988

    1988-01-01

    Arrangements in educational institutions for voluntary early retirement programs are discussed. Retirement at any age can be a profound and stressful lifetime change; and it can also represent a welcome transition into newly satisfying and rewarding opportunities. The focus is on: mandatory retirement (exceptions and the new meaning of "early");…

  8. Voluntary disclosure: Evidence from UK

    NARCIS (Netherlands)

    N.S. Zourarakis (Nicolaos)

    2009-01-01

    textabstractThis paper investigates the voluntary disclosure of Intellectual Capital (IC) of British firms and provides some evidence on an unexplored area of the literature; that of the association of Corporate Governance (CG) with IC disclosure. Inconsistent with expectations, the results show tha

  9. Voluntary sterilization in Serbia: Unmet need?

    OpenAIRE

    Rašević Mirjana M.

    2002-01-01

    Is voluntary sterilization as a birth control method accepted in Serbia? This is certainly a question that is being imposed for research, regardless of the fact that voluntary sterilization is neither accessible nor promoted. Most importantly because there is no understanding in the social nor political sphere for legalization of voluntary sterilization as a form of birth control, apart from the clear necessity for this, first, step. They are: the recognition that voluntary sterilization is a...

  10. 16 CFR 1031.7 - Commission support of voluntary standards activities.

    Science.gov (United States)

    2010-01-01

    ... or subsidizing technical assistance, including research, health science data, and engineering support.... (5) Providing assistance on methods of disseminating information and education about the voluntary... conflicting State and local regulations. (8) Monitoring the number and market share of products conforming...

  11. 75 FR 43486 - Proposed Information Collection; Comment Request; Voluntary Self-Disclosure of Antiboycott...

    Science.gov (United States)

    2010-07-26

    ... Bureau of Industry and Security Proposed Information Collection; Comment Request; Voluntary Self- Disclosure of Antiboycott Violations AGENCY: Bureau of Industry and Security, Commerce ACTION: Notice... Regulations (EAR) by providing a method for industry to voluntarily self-disclose antiboycott violations...

  12. 22 CFR 513.210 - Voluntary exclusion.

    Science.gov (United States)

    2010-04-01

    ... 22 Foreign Relations 2 2010-04-01 2010-04-01 true Voluntary exclusion. 513.210 Section 513.210... GOVERNMENTWIDE REQUIREMENTS FOR DRUG-FREE WORKPLACE (GRANTS) Effect of Action § 513.210 Voluntary exclusion. Persons who accept voluntary exclusions under § 513.315 are excluded in accordance with the terms of...

  13. Effective Phytoextraction of Cadmium (Cd) with Increasing Concentration of Total Phenolics and Free Proline in Cannabis sativa (L) Plant Under Various Treatments of Fertilizers, Plant Growth Regulators and Sodium Salt.

    Science.gov (United States)

    Ahmad, Ayaz; Hadi, Fazal; Ali, Nasir

    2015-01-01

    The comparative effect of fertilizers (NPK), plant growth regulators (GA3, IAA, Zeatin) and sodium chloride (NaCl) on Cd phytoaccumulation, proline and phenolics production in Cannabis sativa was evaluated. Proline and phenolices were correlated with Cd contents in plant. Cd significantly reduced the plant growth. Fertilizers application (in combination) most significantly increased the growth (19 cm root and 47 cm shoot) on Cd contaminated soil. All treatments increased the Cd contents in plant tissues. This increase was highly significant in fertilizers treated plants (1101, 121 and 544 ppm in roots, stem and leaves respectively). Significantly positive correlation was found between Cd concentration and dry biomass of root (R2=0.7511) and leaves (R2=0.5524). All treatments significantly increased the proline and total phenolics and maximum was recorded in NaCl treated plants followed by fertilizers. Proline was higher in roots while phenolics in leaves. The correlation between proline and phenolics was positive in leaf (R2=0.8439) and root (R2=0.5191). Proline and phenolics showed positive correlation with Cd concentration in plant. Conclusively, fertilizers in combination seem to be the better option for Cd phytoextraction. Further investigation is suggested to study the role of phenolics and proline in Cd phytoextraction.

  14. International Voluntary Renewable Energy Markets (Presentation)

    Energy Technology Data Exchange (ETDEWEB)

    Heeter, J.

    2012-06-01

    This presentation provides an overview of international voluntary renewable energy markets, with a focus on the United States and Europe. The voluntary renewable energy market is the market in which consumers and institutions purchase renewable energy to match their electricity needs on a voluntary basis. In 2010, the U.S. voluntary market was estimated at 35 terawatt-hours (TWh) compared to 300 TWh in the European market, though key differences exist. On a customer basis, Australia has historically had the largest number of customers, pricing for voluntary certificates remains low, at less than $1 megawatt-hour, though prices depend on technology.

  15. Effects of Different Fertilizer Rates, Planting Density and Plant Growth Regulators on Yield of Soybean Cultivar Tiedou 68%肥密化控对铁豆68号产量的影响

    Institute of Scientific and Technical Information of China (English)

    董友魁; 刘德恒; 韩艳红

    2015-01-01

    采用正交试验对影响铁豆68号产量的密度、施肥量、叶面喷肥、化控次数4因素进行研究,结果表明,对大豆新品种铁豆68号产量影响的顺序是:施肥量、密度、叶面喷肥、化控次数;铁豆68号最理想的栽培技术模式是密度1.1万株/667m2,施肥量为20 kg/667m2,叶面喷肥1次,化控次数1次。%In order to examine the effects of planting density, fertilization rates, foliar application and times of plant growth regulator application during the growing period of soybean cultivar Tiedou 68, the orthogonal experimental design was used to carry out data analysis. The result indicated that the order of cultivation practices on soybean new variety Tiedou 68 was: fertilization rate, planting density, foliar application and times of plant growth regulator application. The ideal cultural pattern of cultivar Tiedou 68 was planting density of 11 000/667m2, fertilization rate of 20 kg/667m2, and one time of foliar and plant growth regulator application.

  16. Offloading social care responsibilities: recent experiences of local voluntary organisations in a remote urban centre in British Columbia, Canada.

    Science.gov (United States)

    Hanlon, Neil; Rosenberg, Mark; Clasby, Rachael

    2007-07-01

    Services offered by voluntary organisations are an integral but often overlooked component of health and social care. Of late, there has been a renewed interest in voluntary welfare provision as a viable alternative to state and market. Recent developments in welfare provision in Canada appear to have brought greater social care roles for the voluntary sector at the same time as new and arguably more restrictive funding and accountability mechanisms are being imposed by different arms of the state. To explore these issues more closely, the present paper examines the impressions and experiences of voluntary and formal sector providers of services for senior citizens and people with disabilities in a remote urban centre (population less than 100 000) in the interior of British Columbia, Canada. Two important operational pressures provide the context of the analysis: (1) reform of provincial government funding and regulation of voluntary services; and (2) the restructuring of welfare provision, especially in the areas of health care and social services. The authors found evidence of an escalating incursion of the state into local voluntary sector affairs that needs to be understood in the context of long-standing institutional links between government and 'professional' voluntary welfare provision in British Columbia. The results point to three important directions in contemporary local voluntary provision: (1) an emerging ethos of accountability, efficiency and competition in voluntary provision; (2) increasing pressure to centralise volunteer services; and consequently, (3) the potential erosion of flexibility and personalisation that are seen to characterise the voluntary sector.

  17. Regulating effect of strategy of irrigation and fertilization on the formation of quality of wheat%水肥运筹对小麦品质形成的调控效应

    Institute of Scientific and Technical Information of China (English)

    毛凤梧; 赵会杰; 徐立新; 郭宏祥; 杨新志

    2001-01-01

    A study was conducted on the regulating effect of strategy of irrigation and fertilization on the quality of wheat.The results indicated that the strategy of irrigation and fertilization had evident effect on the quality of wheat.With the same amount of nitrogen fertilizer application,deferring top-dressing time,spraying nitrogen fertilizer as well as irrigation during grain-filling stage could enhance the nitrogen metabolism in grain and improve the quality of wheat.%试验结果表明,水肥运筹对小麦品质形成具有明显的调节效应.在相同的施氮量条件下,推迟追氮时期、灌浆期喷氮和浇灌浆水等措施均可增强小麦生育后期的氮代谢转化能力,有利于改善小麦品质.

  18. Status and Trends in the U.S. Voluntary Green Power Market (2012 Data)

    Energy Technology Data Exchange (ETDEWEB)

    Heeter, J. [National Renewable Energy Lab. (NREL), Golden, CO (United States); Nicholas, T. [National Renewable Energy Lab. (NREL), Golden, CO (United States)

    2013-10-01

    The "voluntary" or "green power" market is that in which consumers and institutions voluntarily purchase renewable energy to match all or part of their electricity needs. Voluntary action provides a revenue stream for renewable energy projects and raises consumer awareness of the benefits of renewable energy. There are numerous ways consumers and institutions can purchase renewable energy. Historically, the voluntary market has consisted of three market sectors: (1) utility green pricing programs (in states with regulated electricity markets), (2) competitive suppliers (in states with restructured electricity markets), and (3) unbundled renewable electricity certificate (REC) markets, where RECs are purchased by consumers separately from electricity ("unbundled").

  19. Status and Trends in U.S. Compliance and Voluntary Renewable Energy Certificate Markets (2010 Data)

    Energy Technology Data Exchange (ETDEWEB)

    Heeter, Jenny [National Renewable Energy Lab. (NREL), Golden, CO (United States); Bird, Lori [National Renewable Energy Lab. (NREL), Golden, CO (United States)

    2011-10-01

    The "voluntary" or "green power" market is that in which consumers and institutions voluntarily purchase renewable energy to match all or part of their electricity needs. Voluntary action provides a revenue stream for renewable energy projects and raises consumer awareness of the benefits of renewable energy. There are numerous ways consumers and institutions can purchase renewable energy. Historically, the voluntary market has consisted of three market sectors: (1) utility green pricing programs (in states with regulated electricity markets), (2) competitive suppliers (in states with restructured electricity markets), and (3) unbundled renewable electricity certificate (REC) markets, where RECs are purchased by consumers separately from electricity ("unbundled").

  20. 78 FR 49382 - Voluntary Education Programs

    Science.gov (United States)

    2013-08-14

    ... English, reading, writing, speaking, mathematics, and computer skills that are essential to successful job... education advisor: Education Services Specialist, Education Services Officer (ESO), Voluntary...

  1. Dynamics of Voluntary Cough Maneuvers

    Science.gov (United States)

    Naire, Shailesh

    2008-11-01

    Voluntary cough maneuvers are characterized by transient peak expiratory flows (PEF) exceeding the maximum expiratory flow-volume (MEFV) curve. In some cases, these flows can be well in excess of the MEFV, generally referred to as supramaximal flows. Understanding the flow-structure interaction involved in these maneuvers is the main goal of this work. We present a simple theoretical model for investigating the dynamics of voluntary cough and forced expiratory maneuvers. The core modeling idea is based on a 1-D model of high Reynolds number flow through flexible-walled tubes. The model incorporates key ingredients involved in these maneuvers: the expiratory effort generated by the abdominal and expiratory muscles, the glottis and the flexibility and compliance of the lung airways. Variations in these allow investigation of the expiratory flows generated by a variety of single cough maneuvers. The model successfully reproduces PEF which is shown to depend on the cough generation protocol, the glottis reopening time and the compliance of the airways. The particular highlight is in simulating supramaximal PEF for very compliant tubes. The flow-structure interaction mechanisms behind these are discussed. The wave speed theory of flow limitation is used to characterize the PEF. Existing hypotheses of the origin of PEF, from cough and forced expiration experiments, are also tested using this model.

  2. Application of Chemical Regulating Technology for Utilization of Water and Fertilizer in Dry-land Agriculture%化学调控技术在旱地水肥利用中的应用进展

    Institute of Scientific and Technical Information of China (English)

    杨培岭; 廖人宽; 任树梅; 李云开

    2013-01-01

    The issue on the theme of efficient utilization of water and fertilizer in dry-land agriculture was discussed.The mechanism of action of three typical chemical agents (soil conditioner-PAM,water retaining agent-SAP,antitranspirant-FA) in regulation of water and fertilizer and its application methods were introduced.Research of chemical regulating technology on four important parts were emphatically reviewed (enhancement of the accumulation of water and fertilizer,improvement of the soil and water conservation,improvement of the utilization of crop to water and fertilizer,increasing of the crop yield and quality) in dry-land agriculture production.Finally,the future important research directions were proposed.%围绕旱地农业生产中的水肥资源高效利用展开讨论,主要介绍了以3种典型化学调控制剂(土壤改良剂PAM、土壤保水剂SAP和蒸腾抑制剂FA)为代表的化学调控技术在旱地农业水肥资源利用方面的调控机制和应用方法,重点对化学调控技术在旱地农业生产中的增强水肥保蓄、提高坡地水土保持、改善作物水肥利用性能及提升作物品质和产量4个重要环节上的应用研究进行了综述,最后提出未来化学调控技术在旱地农业中应用的重点研究方向.

  3. 75 FR 47504 - Voluntary Education Programs

    Science.gov (United States)

    2010-08-06

    ... America. TTT helps relieve teacher shortages, especially in math, science, special education, and other... of the Secretary 32 CFR Part 68 RIN 0790-AI50 Voluntary Education Programs AGENCY: Office of the... for the operation of voluntary education programs within DoD. Included are: Procedures for Service...

  4. Pedagogical Aspects of Voluntary School Work

    Science.gov (United States)

    Mária Jármai, Erzsébet; Palányi, Ildikó Zsupanekné

    2015-01-01

    The economic importance of voluntary work has been exceedingly appreciated in the last few decades. This is not surprising at all, because it is highly profitable according to the related estimated data. There are 115,9 million people doing voluntary work only in Europe, which means that they would create the world's 7th biggest economy with EUR…

  5. Changing Dynamics in the Voluntary Market (Presentation)

    Energy Technology Data Exchange (ETDEWEB)

    Heeter, J.

    2014-12-01

    Voluntary green power markets are those in which consumers and institutions voluntarily purchase renewable energy to match their electricity needs. This presentation, presented at the Renewable Energy Markets Conference in December 2014, outlines the voluntary market in 2013, including community choice aggregation and community solar.

  6. 12 CFR 546.4 - Voluntary dissolution.

    Science.gov (United States)

    2010-01-01

    ... 12 Banks and Banking 5 2010-01-01 2010-01-01 false Voluntary dissolution. 546.4 Section 546.4... ASSOCIATIONS-MERGER, DISSOLUTION, REORGANIZATION, AND CONVERSION § 546.4 Voluntary dissolution. A Federal savings association's board of directors may propose a plan for dissolution of the association. The plan...

  7. Between voluntary agreement and legislation

    DEFF Research Database (Denmark)

    Gwozdz, Wencke; Hedegaard, Liselotte; Reisch, Lucia

    2009-01-01

    Voluntary agreements and self-imposed standards are broadly applied to restrict the influence food advertising exerts on children’s food choices – yet their effects are unknown. The current project will therefore investigate whether and, if yes, how the Danish Code for Responsible Food Marketing...... Communication towards Children (hereafter: CODE) – with its dependence on a supportive institutional environment and acceptance of as well as dynamics between involved key stakeholders like consumers, political actors and firms – contributes to fighting the obesity pandemic.Thus, we explore within this article...... what information about the process of implementing the CODE as well as about the evolved dynamics between key stakeholders is already available. Here, the recently published report of the PolMark project sheds light on the dynamics between the key stakeholders in relation to the current Danish...

  8. Regulation of water and fertilizer in banana cultivation in Nanning City%南宁市香蕉栽培水肥调控技术应用研究

    Institute of Scientific and Technical Information of China (English)

    欧桂兰; 陆丹; 刘厚铭

    2011-01-01

    [目的]研究水肥调控对香蕉生产的影响,探索节水、节肥的栽培技术,以提高香蕉种植的经济效益.[方法]通过田间试验,从水肥调控人手,探讨水肥一体化滴灌施肥、喷水带灌溉加人工撒肥、传统的畦沟灌溉施肥3种水肥管理方式对香蕉生长的影响,并对3种灌溉施肥方式下的经济效益进行比较分析.[结果]在一个香蕉生长周期,与传统的畦沟灌溉施肥相比,水肥一体化滴灌技术每公顷节水2788.1~3164.2 t、节肥3582.1~5977.6 kg、节本增效17810.05~44806.15元;喷水带灌溉加人工撒肥每公顷节水2716.4 t、节肥3582.1 kg、节本增效20005.95元.[结论]水肥一体化滴灌施肥和喷水带灌溉加人工撒肥两种灌溉施肥方式均有节水、节肥、增效作用,不同种植人群可根据具体情况选择不同的方式种植香蕉.%The effects of different water and fertilizer regulation practices on banana production were studied in order to find out a water and fertilizer saving cultivation technology and to increase the economic benefits from banana crop. [Method]Three treatments, viz., (1) integrated drip irrigation and fertilizer management; (2) irrigation with water-spraying belt and artificial fertilization; (3) ridge fertilization (traditional management), were used under field conditions and e-conomic benefits were compared. [Result]During one crop cycle of banana, 2788.1-3164.2 t/ha water and 3582.1-5977.6 kg/ha fertilizer were saved in treatment 1 compared to treatment 3, which resulted in economic benefits of 17810.05 - 44806.15 Yuan/ha. Treatment 2 saved 2716.4 t/ha water and 3582.1 kg/ha fertilizer and resulted in economic benefits of 20005.95 Yuan/ha compared to treatment 3. [ Conclusion Jtreatments 1 and 2 both saved water and fertilizer and increased economic benefits from banana production in Nanning City. It was recommended to choose suitable water and fertilizer regulation practices according to local

  9. The effect of phosphate solubilizing microbe producing growth regulators on soil phosphate, growth and yield of maize and fertilizer efficiency on Ultisol

    Directory of Open Access Journals (Sweden)

    Betty Natalie Fitriatin

    2014-04-01

    Full Text Available Ultisol is soil that have problem of soil acidity, low organic matter and low available macro nutrient in particularly low P availability. This is only small part of phosphorus is available for plant because most of the phosphate was still present in the soil were fixed by soil colloids. Some soil microbes are known phosphate solubilizing microbes have capability to dissolve phosphate that transform of P fixed into the soluble P. The field experiment conducted at Jatinangor, West Java Indonesia to determine the effect of PSM on phosphate solubility, growth and yield of maize and phosphorus fertilizer efficiency. Design experiment of Randomized Block Design (RBD was used in field experiment, consisted of two factors and three replications. Phosphate solubilizing microbe as the first factor consisted four levels i.e without, phosphate solubilizing bacteria (PSB, phosphate solubilizing fungi (PSF, mixture of PSB and PSF. While the second factor was P fertilizer consists five levels (0%, 25%, 50%, 75% and 100% doses of recomendation. The results of the field experiment showed that application of phosphate solubilizing microbes significantly improve the yield of maize in Ultisol Jatinangor, but did not significantly affect on soil P, available soil P, phosphatase and P uptake of plants. Application of a mixture of PSB and PSF better effect on soil available P and yield of maize. Phospate fertilizer dosing at a dose of 25 % , 50 % , 75 % and 100 % recommendations increased available soil P. Fertilizer of P could inhibit the activity of phosphatases. Phosphate fertilizer with dose 50 % recommendation gave better effect on soil P and yield of maize.

  10. Fertilization in northern forests

    DEFF Research Database (Denmark)

    Hedwall, Per Ola; Gong, Peichen; Ingerslev, Morten

    2014-01-01

    resources into food, health and industrial products and energy. Fertilization in Sweden and Finland is currently practiced by extensive fertilization regimens where nitrogen fertilizers are applied once, or up to three times, during a rotation period, mainly in mature forest. This type of fertilization...

  11. AN ECONOMETRIC APPROACH ABOUT VOLUNTARY TURNOVER

    Directory of Open Access Journals (Sweden)

    ADALET EREN

    2013-06-01

    Full Text Available This study analyzes individual and organizational variables that affect voluntary turnover are determined in the special defence and security companies. A binomial logistic regression model is used to estimate voluntary turnover.  Binomial Logistic regression, reliability test (scale alfa, variance (ANOVA, Post-hoc/Tukey, correlation (Pearson and other basic statistical techniques  with SPSS 13 statistical packet program was used in the analyzes ofresearch data. The study finds that; situation of suppose working, number of child, number of death child, number of home’s moving, support of rent, total monthly income of household, last work’s region, number of prizes, affect voluntary turnover are determined.

  12. Malthus to Modernity: England’s First Fertility Transition, 1760-1800

    OpenAIRE

    Clark, Gregory; Cummins, Neil

    2010-01-01

    English fertility history is generally regarded as having been composed of two re-gimes: an era of unregulated marital fertility, from at least 1540 to 1890, then the modern era, with regulated marital fertility, lower for higher social classes. We show there were in fact three fertility regimes in England: a Malthusian regime which lasted from at least 1500 until 1780, where fertility was substantially higher for the rich, an intermediate regime from 1780 to 1890 with fertility undifferenti...

  13. Molecular, cellular, and physiological determinants of bull fertility

    OpenAIRE

    PARISI, Alexis Marie; THOMPSON, Shannon Kate; Kaya, Abdullah; MEMİLİ, Erdoğan

    2014-01-01

    Bull fertility, defined as the ability of the spermatozoon to fertilize and activate the ovum and then support embryonic and even fetal development, is a crucial factor influencing animal reproduction and production efficiency. Despite significant influences of fertility on herd genetic improvement and efficient cattle production, the mechanisms regulating this phenotype and reliable biomarkers associated with bull fertility are poorly defined. Specifically, there is a broad lack of knowledge...

  14. Negative emotional outcomes attenuate sense of agency over voluntary actions.

    Science.gov (United States)

    Yoshie, Michiko; Haggard, Patrick

    2013-10-21

    Sense of agency (SoA) refers to the feeling that one's voluntary actions produce external sensory events [1, 2]. Several psychological theories hypothesized links between SoA and affective evaluation [3-6]. For example, people tend to attribute positive outcomes to their own actions, perhaps reflecting high-level narrative processes that enhance self-esteem [3]. Here we provide the first evidence that such emotional modulations also involve changes in the low-level sensorimotor basis of agency. The intentional binding paradigm [1] was used to quantify the subjective temporal compression between a voluntary action and its sensory consequences, providing an implicit measure of SoA. Emotional valence of action outcomes was manipulated by following participants' key-press actions with negative or positive emotional vocalizations [7], or neutral sounds. We found that intentional binding was reduced for negative compared to positive or neutral outcomes. Discriminant analyses identified a change in time perception of both actions and their negative outcomes, demonstrating that the experience of action itself is subject to affective modulation. A small binding benefit was also found for positive action outcomes. Emotional modulation of SoA may contribute to regulating social behavior. Correctly tracking the valenced effects of one's voluntary actions on other people could underlie successful social interactions.

  15. Characterization of aurora-a in porcine oocytes and early embryos implies its functional roles in the regulation of meiotic maturation, fertilization and cleavage.

    Science.gov (United States)

    Yao, Li-Juan; Sun, Qing-Yuan

    2005-02-01

    Aurora-A is a serine/threonine protein kinase that plays important regulatory roles during mitotic cell cycle progression. In this study, Aurora-A expression, subcellular localization, and possible functions during porcine oocyte meiotic maturation, fertilization and early embryonic cleavage were studied by using Western blot, confocal microscopy and drug treatments. The quantity of Aurora-A protein remained stable during porcine oocyte meiotic maturation. Confocal microscopy revealed that Aurora-A distributed abundantly in the nucleus at the germinal vesicle stage. After germinal vesicle breakdown, Aurora-A concentrated around the condensed chromosomes and the metaphase I spindle, and finally, Aurora-A was associated with spindle poles during the formation of the metaphase II spindle. Aurora-A concentrated in the pronuclei in fertilized eggs. Aurora-A was not found in the spindle region when colchicine or staurosporine was used to inhibit microtubule organization, while it accumulated as several dots in the cytoplasm after taxol treatment. In conclusion, Aurora-A may be a multifunctional kinase that plays pivotal regulatory roles in microtubule assembly during porcine oocyte meiotic maturation, fertilization and early embryonic mitosis.

  16. Anticipatory signatures of voluntary memory suppression.

    Science.gov (United States)

    Hanslmayr, Simon; Leipold, Philipp; Pastötter, Bernhard; Bäuml, Karl-Heinz

    2009-03-04

    Voluntary memory suppression can keep unwanted memories from entering consciousness, inducing later forgetting of the information. In the present study, we searched for the existence of anticipatory processes, mediating such voluntary memory suppression. Using the think/no-think paradigm, subjects received a cue whether to prepare to think of a previously studied cue-target pair or whether to not let a previously studied cue-target pair enter consciousness. Examining event-related potentials, we identified two electrophysiological processes of voluntary memory suppression: (1) an early anticipatory process operating before the memory cue for a to-be-suppressed memory was provided, and (2) a later process operating after memory cue presentation. Both ERP effects were due to a decreased right frontal and left parietal positivity. They were positively related and predicted later forgetting. The results point to the existence of anticipatory processes, mediating voluntary memory suppression.

  17. Pedagogical Aspects of Voluntary School Work

    Directory of Open Access Journals (Sweden)

    Mária Jármai Erzsébet

    2015-03-01

    Full Text Available The economic importance of voluntary work has been exceedingly appreciated in the last few decades. This is not surprising at all, because it is highly profitable according to the related estimated data. There are 115,9 million people doing voluntary work only in Europe, which means that they would create the world's 7th biggest economy with EUR 282 billion value creation if they formed an individual state. The organizations know that voluntary work has several advantages apart from the economic benefits. It is profitable both for the society and for the individuals as well. Several researches have proven that voluntary work positively influences the development of the personality, because the key-competencies - such as: co-operation, empathy, solidarity, conflict handling, problem solving, etc. - expected in the labor market can be improved.

  18. Managing voluntary turnover through challenging assignments

    NARCIS (Netherlands)

    Preenen, P.T.Y.; Pater, I.E. de; Vianen, A.E.M. van; Keijzer, L.

    2011-01-01

    This study examines employees' challenging assignments as manageable means to reduce turnover intentions, job search behaviors, and voluntary turnover. Results indicate that challenging assignments are negatively related to turnover intentions and job search behaviors and that these relationships

  19. Corticospinal excitability in human voluntary movement

    NARCIS (Netherlands)

    Elswijk, G.A.F. van

    2008-01-01

    The research described in this thesis addressed the neurophysiologic changes in the human corticospinal system during preparation and execution of voluntary hand movements. The experiments involved transcranial magnetic stimulation (TMS) of the motor cortex combined with electromyography (EMG) and e

  20. Contemplated Suicide Among Voluntary and Involuntary Retirees

    Science.gov (United States)

    Peretti, Peter O.; Wilson, Cedric

    1978-01-01

    This study explored anomic and egoistic dimensions of contemplated suicide among voluntary and involuntary retired males. Results indicated a direct relationship between anomie and egoism on the one hand, and contemplation of suicide on the other. (Author)

  1. A Free Market Requires Voluntary Actions

    DEFF Research Database (Denmark)

    Sløk-Madsen, Stefan Kirkegaard

    are essential to the construct of consumer sovereignty. Understanding the degree of voluntary actions in a given commercial setting has implications for both business strategy and policy making. This paper thus aims to contribute to explain why restricted markets become crony capitalism.......This paper draws attention to the importance of the understanding of voluntary actions in the free market construct. Failing to understand the role of voluntary actions in the free market construct will often result in discussions of capitalism versus socialism focusing on asset ownership...... and not consumer sovereignty. I argue that asset ownership is less important than true consumer sovereignty, which again is the essential argument for why capitalism is the superior mode of resource allocation and social organization. The paper analyzes how our understanding of markets and voluntary actions...

  2. Contemplated Suicide Among Voluntary and Involuntary Retirees

    Science.gov (United States)

    Peretti, Peter O.; Wilson, Cedric

    1978-01-01

    This study explored anomic and egoistic dimensions of contemplated suicide among voluntary and involuntary retired males. Results indicated a direct relationship between anomie and egoism on the one hand, and contemplation of suicide on the other. (Author)

  3. A rapprochement of the operant-conditioning and awareness views of biofeedback training: the role of discrimination in voluntary control.

    Science.gov (United States)

    Plotkin, W B

    1981-09-01

    In order to adequately evaluate Cott, Pavloski and Black's claim that the discrimination of a physiological response is not necessary for the voluntary control of that response, this commentary presents a set of formal articulations and clarifications of intentional action, voluntary control, discrimination, awareness, and physiological response. It is concluded on logical grounds that Cott et al. are necessarily mistaken and that the conceptual foundations of the issue have not been clearly articulated heretofore. Based upon this discussion, a rapprochement is offered of the operant conditioning and awareness views of biofeedback training, demonstrating that the awareness view is essentially a tautology that aids us in understanding what is meant by "voluntary control of the physiological response." Finally, the issue of mediation in biofeedback-augmented self-regulation is reconceptualized and it is argued that the search for a "neurophysiological mechanism" of voluntary control is meaningless, reflecting a misappropriation of the concept of voluntary control.

  4. Pull factors of Finland and voluntary work

    OpenAIRE

    Jurvakainen, Janika

    2016-01-01

    This thesis studies pull factors of Finland and voluntary work. The aim of this study is to understand the pull factors of Finland from the perspective of young travelers. Which pull factors attract to choose Finland as their destination? In addition, which pull factors attract young travelers to participate in international voluntary work? The commissioner of this thesis is Allianssi Youth Exchange. The thesis is research-based and includes a quantitative Webropol survey and some qualit...

  5. 47 CFR 80.310 - Watch required by voluntary vessels.

    Science.gov (United States)

    2010-10-01

    ... Watches § 80.310 Watch required by voluntary vessels. Voluntary vessels not equipped with DSC must.... Voluntary vessels equipped with VHF-DSC equipment must maintain a watch on 2182 kHz and on either 156.525... used to communicate. Voluntary vessels equipped with MF-HF DSC equipment must have the radio turned...

  6. Status and Trends in U.S. Compliance and Voluntary Renewable Energy Certificate Markets (2010 Data)

    Energy Technology Data Exchange (ETDEWEB)

    Heeter, J.; Bird, L.

    2011-10-01

    This report documents the status and trends of 'compliance'--renewable energy certificate (REC) markets used to meet state renewable portfolio standard (RPS) requirements--and 'voluntary' markets--those in which consumers and institutions purchase renewable energy to match their electricity needs on a voluntary basis. Today, 29 states and the District of Columbia have an RPS, more than half of all U.S. electricity customers have an option to purchase some type of green power product directly from a retail electricity provider, and all consumers have the option to purchase RECs. This report documents REC activities and trends in the United States. The compliance REC market analysis includes analysis of REC trading, regional REC markets, REC tracking systems, types of compliance RECs, compliance REC pricing trends, and an overview of compliance with RPS polices. The voluntary REC analysis presents data and analysis on voluntary market sales and customer participation, products and premiums, green pricing marketing and administrative expenses, voluntary REC pricing, and the voluntary carbon offsets market. The report concludes with a discussion of upcoming guidance from the Federal Trade Commission on green marketing claims, the emergence of community solar programs, and the potential impact of Dodd-Frank regulations on the REC market.

  7. [Thyroid gland and fertility].

    Science.gov (United States)

    Andreeva, P

    2014-01-01

    It is well-known that the thyroid hormones are associated with a number of aspects of the human reproduction. Both states, hyperthyroidism and hypothyroidism, have significant effect on the estrogen and androgen metabolism, the menstrual function and on fertility. The role of thyroid hormones (TH) during infertility has been little exploited. Interesting facts are that TH deficiency is more common in women with polycystic ovary syndrome (PCOS) and in certain cases with unexplained infertility. There are very few studies on the effect and paracrine regulation of TH and its receptors in the female reproductive tract. This report provides an overview of the most common thyroid disorders and their impact on ovarian function and reproductive performance in women as well as in cases with infertility and the implementation of assisted reproductive technologies (ART).

  8. Cancer and fertility : strategies to preserve fertility

    NARCIS (Netherlands)

    Diedrich, K.; Fauser, B. C. J. M.; Devroey, P.

    2011-01-01

    Fertility preservation is a key component of cancer management in young people. The Fourth Evian Annual Reproduction Workshop Meeting was held in April 2009 to discuss cancer and fertility in young adults. Specialists in oncology, assisted reproduction, embryology and clinical genetics presented pub

  9. Cancer and fertility : strategies to preserve fertility

    NARCIS (Netherlands)

    Diedrich, K.; Fauser, B. C. J. M.; Devroey, P.

    Fertility preservation is a key component of cancer management in young people. The Fourth Evian Annual Reproduction Workshop Meeting was held in April 2009 to discuss cancer and fertility in young adults. Specialists in oncology, assisted reproduction, embryology and clinical genetics presented

  10. Voluntary control of human jaw stiffness.

    Science.gov (United States)

    Shiller, Douglas M; Houle, Guillaume; Ostry, David J

    2005-09-01

    Recent studies of human arm movement have suggested that the control of stiffness may be important both for maintaining stability and for achieving differences in movement accuracy. In the present study, we have examined the voluntary control of postural stiffness in 3D in the human jaw. The goal is to address the possible role of stiffness control in both stabilizing the jaw and in achieving the differential precision requirements of speech sounds. We previously showed that patterns of kinematic variability in speech are systematically related to the stiffness of the jaw. If the nervous system uses stiffness control as a means to regulate kinematic variation in speech, it should also be possible to show that subjects can voluntarily modify jaw stiffness. Using a robotic device, a series of force pulses was applied to the jaw to elicit changes in stiffness to resist displacement. Three orthogonal directions and three magnitudes of forces were tested. In all conditions, subjects increased the magnitude of jaw stiffness to resist the effects of the applied forces. Apart from the horizontal direction, greater increases in stiffness were observed when larger forces were applied. Moreover, subjects differentially increased jaw stiffness along a vertical axis to counteract disturbances in this direction. The observed changes in the magnitude of stiffness in different directions suggest an ability to control the pattern of stiffness of the jaw. The results are interpreted as evidence that jaw stiffness can be adjusted voluntarily, and thus may play a role in stabilizing the jaw and in controlling movement variation in the orofacial system.

  11. Age and Fertility

    Science.gov (United States)

    ... method of assisted reproduction that involves combining an egg with sperm in a laboratory dish. If the egg fertilizes ... produced by the testes that fertilize a woman’s egg. The sperm head carries genetic material (chromosomes), the midpiece produces ...

  12. Plant fertilizer poisoning

    Science.gov (United States)

    Plant fertilizers and household plant foods are used to improve plant growth. Poisoning can occur if someone swallows these products. Plant fertilizers are mildly poisonous if small amounts are swallowed. ...

  13. Fertility Clinic Success Rates

    Science.gov (United States)

    ... and Autism 2013 Assisted Reproductive Technology Fertility Clinic Success Rates Report Recommend on Facebook Tweet Share Compartir 2013 ART Fertility Clinic Success Rates Report [PDF - 1MB] Bookmarks and thumbnails are ...

  14. In vitro fertilization (IVF)

    Science.gov (United States)

    ... medlineplus.gov/ency/article/007279.htm In vitro fertilization (IVF) To use the sharing features on this page, please enable JavaScript. In vitro fertilization (IVF) is the joining of a woman's egg ...

  15. Molecular aspects of mammalian fertilization

    Institute of Scientific and Technical Information of China (English)

    Hector Serrano; Dolores Garcia-Suarez

    2001-01-01

    Mammalian fertilization is a highly regulated process, much of which are not clearly understood. Here we present some information in order to elaborate a working hypothesis for this process, beginning with the sperm modifications in the epidydimis up to sperm and egg plasmalemma interaction and fusion. We also discuss the still poorly understood capacitation process, the phenomenon of sperm chemo-attraction that brings the capacitated sperm to interact with the oocyte vestments and certain aspects of the acrosome reaction.

  16. Voluntary attention increases perceived spatial frequency.

    Science.gov (United States)

    Abrams, Jared; Barbot, Antoine; Carrasco, Marisa

    2010-08-01

    Voluntary covert attention selects relevant sensory information for prioritized processing. The behavioral and neural consequences of such selection have been extensively documented, but its phenomenology has received little empirical investigation. Involuntary attention increases perceived spatial frequency (Gobell & Carrasco, 2005), but involuntary attention can differ from voluntary attention in its effects on performance in tasks mediated by spatial resolution (Yeshurun, Montagna, & Carrasco, 2008). Therefore, we ask whether voluntary attention affects the subjective appearance of spatial frequency--a fundamental dimension of visual perception underlying spatial resolution. We used a demanding rapid serial visual presentation task to direct voluntary attention and measured perceived spatial frequency at the attended and unattended locations. Attention increased the perceived spatial frequency of suprathreshold stimuli and also improved performance on a concurrent orientation discrimination task. In the control experiment, we ruled out response bias as an alternative account by using a lengthened interstimulus interval, which allows observers to disengage attention from the cued location. In contrast to the main experiment, the observers showed neither increased perceived spatial frequency nor improved orientation discrimination at the attended location. Thus, this study establishes that voluntary attention increases perceived spatial frequency. This phenomenological consequence links behavioral and neurophysiological studies on the effects of attention.

  17. Cancer and fertility: strategies to preserve fertility.

    Science.gov (United States)

    Diedrich, K; Fauser, B C J M; Devroey, P

    2011-03-01

    Fertility preservation is a key component of cancer management in young people. The Fourth Evian Annual Reproduction Workshop Meeting was held in April 2009 to discuss cancer and fertility in young adults. Specialists in oncology, assisted reproduction, embryology and clinical genetics presented published data and ongoing research on cancer and fertility, with particular focus on strategies to preserve fertility. This report is based on the expert presentations and group discussions, supplemented with publications from literature searches and the authors' knowledge. Fertility preservation should be considered for all young people undergoing potentially gonadotoxic cancer treatment. A variety of options are required to facilitate safe and effective fertility preservation for individual patients. Sperm banking is a simple and low-cost intervention. Embryo cryopreservation is the only established method of female fertility preservation. Oocyte cryopreservation offers a useful option for women without a male partner. Emergency ovarian stimulation and cryopreservation of ovarian tissue (followed by tissue transplantation or in-vitro maturation of oocytes) are experimental techniques for women who require urgent cancer treatment. Further prospective studies are required to validate cryopreservation of oocytes and ovarian tissue, in-vitro maturation of oocytes and new vitrification techniques and to identify any long-term sequelae of slow freezing of embryos.

  18. 41 CFR 105-68.640 - May a settlement include a voluntary exclusion?

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false May a settlement include a voluntary exclusion? 105-68.640 Section 105-68.640 Public Contracts and Property Management Federal Property Management Regulations System (Continued) GENERAL SERVICES ADMINISTRATION...

  19. 75 FR 28780 - Proposed Information Collection; Comment Request; Procedure for Voluntary Self-Disclosure of...

    Science.gov (United States)

    2010-05-24

    ... Self-Disclosure of Violations of the Export Administration Regulations AGENCY: Bureau of Industry and... investigation or prosecution is necessary and to reach a settlement with violators. Voluntary self-disclosure of... disclosures. BIS evaluates the seriousness of the violation and either (1) Informs the person making the...

  20. 78 FR 9709 - Draft Guidance Regarding Voluntary Inspection of Vessels for Compliance With the Maritime Labour...

    Science.gov (United States)

    2013-02-11

    ... Maritime Labour Convention, 2006 AGENCY: Coast Guard, DHS. ACTION: Notice of availability and request for.... vessels for voluntary compliance with the Maritime Labour Convention, 2006 (Convention), which enters into... http://www.regulations.gov on or before March 13, 2013 or reach the Docket Management Facility by...

  1. From Voluntary Collective Action to Organized Collaboration?

    DEFF Research Database (Denmark)

    Hattke, Fabian; Blaschke, Steffen; Frost, Jetta

    2016-01-01

    internationalization. Based on our results, we suggest that, depending on the field of action, voluntary collective action and organized collaboration are substitutes with regard to performance. Our study contributes to the literature on collective action and to research on public organizations in pluralistic......Our study examines the relationship between voluntary collective action, organized collaboration, and the provision of public goods in pluralistic organizations. Using German higher education as a context, we investigate whether specialized central support structures contribute to performance...... in three fields of action: the training of young scientists, internationalization, and gender diversity. The findings indicate that organized collaboration may lead to improved performance in the training of young scientists and gender diversity. Conversely, voluntary collective action enhances...

  2. Voluntary reporting of greenhouse gases, 1995

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-07-01

    The Voluntary Reporting Program for greenhouse gases is part of an attempt by the U.S. Government to develop innovative, low-cost, and nonregulatory approaches to limit emissions of greenhouse gases. It is one element in an array of such programs introduced in recent years as part of the effort being made by the United States to comply with its national commitment to stabilize emissions of greenhouse gases under the Framework Convention on Climate Change. The Voluntary Reporting Program, developed pursuant to Section 1605(b) of the Energy Policy Act of 1992, permits corporations, government agencies, households, and voluntary organizations to report to the Energy Information Administration (EIA) on actions taken that have reduced or avoided emissions of greenhouse gases.

  3. Expression of two different sulfated fucans by females of Lytechinus variegatus may regulate the seasonal variation in the fertilization of the sea urchin.

    Science.gov (United States)

    Cinelli, Leonardo P; Castro, Michelle O; Santos, Livia L; Garcia, Clarice R; Vilela-Silva, Ana-Cristina E S; Mourão, Paulo A S

    2007-08-01

    The egg jellies of sea urchins contain sulfated polysaccharides with unusual structures, composed of linear chains of l-fucose or l-galactose with well-defined repetitive units. The specific pattern of sulfation and the position of the glycosidic bond vary among sulfated polysaccharides from different species. These polysaccharides show species specificity in inducing the acrosome reaction, which is a critical event for fertilization. Females of the sea urchin Lytechinus variegatus spawn eggs containing a sulfated fucan with the repetitive sequence [3-alpha-L-Fucp-2(OSO(3))-1 --> 3-alpha-L-Fucp-4(OSO(3))-1 --> 3-alpha-L-Fucp-2,4(OSO(3))-1 --> 3-alpha-L-Fucp-2(OSO(3))-1](n). We now observe that, close to winter, a period of decreased fertility for the sea urchin, the females synthesize a distinct sulfated fucan with a simple structure, composed of 4-sulfated, 3-linked alpha-fucose residues. This sulfated fucan is inactive when tested in vitro for the acrosome reaction using homologous sperm. The amount of egg jellies spawned by females (and their constituent sulfated polysaccharides) varied greatly throughout the year. Apparently, there is a correlation between the temperature of the sea water and the expression of the 4-sulfated, 3-linked sulfated fucan. Overall, we described the occurrence of two isotypes of sulfated fucan in the egg jelly of the sea urchin L. variegatus, which differ in their biological activity and may be involved in the periodicity of the reproductive cycle of the invertebrate.

  4. Hemochromatosis Patients as Voluntary Blood Donors

    Directory of Open Access Journals (Sweden)

    Tara E Power

    2004-01-01

    Full Text Available The present study was designed to investigate hemochromatosis patients' suitability as blood donors as well as their perceptions and experience with the current public donation system. Participants were gathered from a list of current hemochromatosis patients (n=120 and members of the Canadian Hemochromatosis Society (n=1000. Of the 1120 surveys mailed out to these groups, 801 surveys were returned completed. The sample respondents had a mean age of 57.44 years (SD=12.73; range 19 to 87 years, and 57% were men. It was found that 20% (160 of the respondents have donated blood since their diagnosis; however, only 12% of the respondents indicated that they use voluntary blood donation as a means of maintaining their iron levels. Forty per cent of the respondents indicated that they had been refused from voluntary donation. Despite the fact that in May 2001 the Canadian Blood Services, in collaboration with the Canadian Hemochromatosis Society, began a promotion campaign to encourage hemochromatosis patients to become voluntary blood donors, the present study found that 15% of the respondents reported having been refused from the voluntary blood donation service due to the diagnosis of hemochromatosis. With respect to quality of life, it was found that individuals who donate blood were generally healthier with respect to physical functioning and bodily pain, however, these findings may indicate that hemochromatosis patients who are healthier are better able to donate at public blood banks, rather than that voluntary blood donation has an effect on the donors' physical functioning over phlebotomy clinic users. These study findings suggest that although there may be other medical factors limiting individuals from donating, hemochromatosis patients are interested in being voluntary blood donors and this potential resource is currently under-used.

  5. The institutional dynamics of voluntary organisations

    DEFF Research Database (Denmark)

    Aagaard, Peter

    this theoretical frame to analyse case studies of three voluntary organisations.  As a part of the analysis I describe four sets of institutional settings that can influence voluntary organisations ability to create institutional dynamic: institutionalization, moderation, self-organisation and loose-coupling....... organisations. I establish a theoretical frame of institutional dynamic, build primarily on J.G. March's theory on exploration and exploitation. I focus on two organisational arrangements drawn from the theory: The degree of strategic decision-making and the degree of diversity among the volunteers. I use...

  6. 77 FR 72941 - Voluntary Education Programs

    Science.gov (United States)

    2012-12-07

    ... decision will be made by the selected DoD contractor for the complete `third party review' process. Comment... seeks to enhance the educational opportunities to Service members who may have difficulty in completing... transitions to second careers in teaching. Voluntary education programs. Continuing, adult, or...

  7. Decentralized trade with bargaining and voluntary matching

    DEFF Research Database (Denmark)

    Tranæs, Torben; Sloth, Birgitte; Hendon, Ebbe

    1994-01-01

    Rubinstein and Wolinsky (1990) study a market with one seller, two buyers, and voluntary matching. Both the competitive outcomepc and the bilateral bargaining outcomepb are possible in subgame perfect equilibrium. We consider two variations. First, if there is a cost larger thanpc−pc to the seller...

  8. Social orienting: reflexive versus voluntary control.

    Science.gov (United States)

    Hill, Julia L; Patel, Saumil; Gu, Xue; Seyedali, Nassim S; Bachevalier, Jocelyne; Sereno, Anne B

    2010-09-24

    Many studies have shown that the direction of gaze of a face covertly facilitates the response to a target presented in the matching direction. In this study we seek to determine whether there exist separate reflexive and voluntary forms of such covert social orienting and how they interact with each other. We measured the effect of the predictive value of a gaze cue on manual choice reaction times. When the predictive value of the gaze cue was zero, a facilitatory cueing effect was still observed which peaked at a cue onset to target onset delay (CTD) of 150ms and largely diminished beyond a CTD of 500ms. When the gaze cue was 100% predictive of the future location of the target, at CTDs greater than 200, the predictive cue resulted in a significantly greater facilitation of response than occurred with a non-predictive cue. These results suggest that given enough time (about 200ms), the social cue is interpreted and a willful or voluntary spatially-specific social cueing effect occurs. In addition, we found that a predictive cue resulted in a significant slowing of the observer's responses up to a CTD of 200ms. These findings show that, similar to non-social spatial orienting, there appear to be two forms of social orienting including a reflexive component and voluntary component. We suggest a model of social orienting in which the voluntary social orienting system modulates tonic inhibition of the reflexive social orienting system. Published by Elsevier Ltd.

  9. Equality, self‐respect and voluntary separation

    NARCIS (Netherlands)

    M.S. Merry

    2012-01-01

    This paper argues that self‐respect constitutes an important value, and further, an important basis for equality. It also argues that under conditions of inequality‐producing segregation, voluntary separation in schooling may be more likely to provide the resources necessary for self‐respect. A prim

  10. School Ethical Climate and Teachers' Voluntary Absence

    Science.gov (United States)

    Shapira-Lishchinsky, Orly; Rosenblatt, Zehava

    2010-01-01

    Purpose: This paper aims to offer a theoretical framework for linking school ethical climate with teachers' voluntary absence. The paper attempts to explain this relationship using the concept of affective organizational commitment. Design/methodology/approach: Participants were 1,016 school teachers from 35 high schools in Israel. Data were…

  11. Voluntary Oral Administration of Losartan in Rats.

    Science.gov (United States)

    Diogo, Lucília N; Faustino, Inês V; Afonso, Ricardo A; Pereira, Sofia A; Monteiro, Emília C; Santos, Ana I

    2015-09-01

    Gavage is a widely performed technique for daily dosing in laboratory rodents. Although effective, gavage comprises a sequence of potentially stressful procedures for laboratory animals that may introduce bias into experimental results, especially when the drugs to be tested interfere with stress-dependent parameters. We aimed to test vehicles suitable for drug delivery by voluntary ingestion in rats. Specifically, Male Wistar rats (age, 2 to 3 mo) were used to test nut paste (NUT), peanut butter (PB), and sugar paste (SUG) as vehicles for long-term voluntary oral administration of losartan, an angiotensin II receptor blocker. Vehicles were administered for 28 d without drug to assess effects on the glucose level and serum lipid profile. Losartan was mixed with vehicles and either offered to the rats or administered by gavage (14 d) for subsequent quantification of losartan plasma levels by HPLC. After a 2-d acclimation period, all rats voluntarily ate the vehicles, either alone or mixed with losartan. NUT administration reduced blood glucose levels. The SUG group had higher concentrations of losartan than did the gavage group, without changes in lipid and glucose profiles. Our results showed that NUT, PB, and SUG all are viable for daily single-dose voluntary ingestion of losartan and that SUG was the best alternative overall. Drug bioavailability was not reduced after voluntary ingestion, suggesting that this method is highly effective for chronic oral administration of losartan to laboratory rodents.

  12. Staff's perceptions of voluntary assertiveness skills training.

    Science.gov (United States)

    McVanel, Sarah; Morris, Beth

    2010-01-01

    Clinicians' ability to be assertive when unsure or concerned about procedures, treatment modalities, or patients' symptoms is key in reducing risk and preventing sentinel events. In this article, the authors provide a framework for generic, voluntary assertiveness communication skills workshops that any educator can implement.

  13. Voluntary Organizations: Commitment, Leadership, and Organizational Effectiveness

    Science.gov (United States)

    Ekeland, Terry P.

    2004-01-01

    Voluntary organizations offer a unique opportunity to interpret participant relationships, leadership influences, and organizational effectiveness unencumbered by employment relationships. Regardless of organizational structure or purpose, all organizations are affected to some degree by their leadership and their membership. Based on the…

  14. Environmental Voluntary Agreements in the Dutch Context

    NARCIS (Netherlands)

    Bressers, Johannes T.A.; de Bruijn, Theo; Croci, Edoardo

    2005-01-01

    This paper describes and analyses the use of environmental voluntary agreements, or covenants, in Dutch environmental policy. Covenants have become a widely used policy instrument in the Netherlands. This trend reinforces the strong neo-corporatist traits of Dutch society with its tendency towards

  15. Voluntary Community Organisations in Metropolitan Development

    DEFF Research Database (Denmark)

    Larsen, Jacob Norvig

    While short-term enrolling of citizens in urban regeneration projects often has proven quite successful, permanent embedding of projects in voluntary community-based settings seems to be much more difficult to obtain. This has implications for long term sustainability of urban regeneration projec...

  16. Early Maternal Deprivation Enhances Voluntary Alcohol Intake Induced by Exposure to Stressful Events Later in Life

    Directory of Open Access Journals (Sweden)

    Sara Peñasco

    2015-01-01

    Full Text Available In the present study, we aimed to assess the impact of early life stress, in the form of early maternal deprivation (MD, 24 h on postnatal day, pnd, 9, on voluntary alcohol intake in adolescent male and female Wistar rats. During adolescence, from pnd 28 to pnd 50, voluntary ethanol intake (20%, v/v was investigated using the two-bottle free choice paradigm. To better understand the relationship between stress and alcohol consumption, voluntary alcohol intake was also evaluated following additional stressful events later in life, that is, a week of alcohol cessation and a week of alcohol cessation combined with exposure to restraint stress. Female animals consumed more alcohol than males only after a second episode of alcohol cessation combined with restraint stress. MD did not affect baseline voluntary alcohol intake but increased voluntary alcohol intake after stress exposure, indicating that MD may render animals more vulnerable to the effects of stress on alcohol intake. During adolescence, when animals had free access to alcohol, MD animals showed lower body weight gain but a higher growth rate than control animals. Moreover, the higher growth rate was accompanied by a decrease in food intake, suggesting an altered metabolic regulation in MD animals that may interact with alcohol intake.

  17. Early maternal deprivation enhances voluntary alcohol intake induced by exposure to stressful events later in life.

    Science.gov (United States)

    Peñasco, Sara; Mela, Virginia; López-Moreno, Jose Antonio; Viveros, María-Paz; Marco, Eva M

    2015-01-01

    In the present study, we aimed to assess the impact of early life stress, in the form of early maternal deprivation (MD, 24 h on postnatal day, pnd, 9), on voluntary alcohol intake in adolescent male and female Wistar rats. During adolescence, from pnd 28 to pnd 50, voluntary ethanol intake (20%, v/v) was investigated using the two-bottle free choice paradigm. To better understand the relationship between stress and alcohol consumption, voluntary alcohol intake was also evaluated following additional stressful events later in life, that is, a week of alcohol cessation and a week of alcohol cessation combined with exposure to restraint stress. Female animals consumed more alcohol than males only after a second episode of alcohol cessation combined with restraint stress. MD did not affect baseline voluntary alcohol intake but increased voluntary alcohol intake after stress exposure, indicating that MD may render animals more vulnerable to the effects of stress on alcohol intake. During adolescence, when animals had free access to alcohol, MD animals showed lower body weight gain but a higher growth rate than control animals. Moreover, the higher growth rate was accompanied by a decrease in food intake, suggesting an altered metabolic regulation in MD animals that may interact with alcohol intake.

  18. Eligibility and Exclusion of Hemochromatosis Patients as Voluntary Blood Donors

    Directory of Open Access Journals (Sweden)

    M Levstik

    1998-01-01

    Full Text Available BACKGROUND: Hereditary hemochromatosis patients are excluded in many countries as voluntary blood donors. In 1991, changes in the Canadian Red Cross policy allowed healthy hemochromatosis patients to become voluntary donors.

  19. Results of the global survey on Voluntary Sustainability Standards

    OpenAIRE

    Lernoud, Julia

    2015-01-01

    Results of the global survey on Voluntary Sustainability Standards: - Voluntary Sustainability Standards (VSS) area worldwide and selected commodities - Cocoa: Area growth by VSS 2008-2014 - Growth of VSS compliant area worldwide 2008-2013 (selected crops)

  20. China Initiates Voluntary Certification of Public Security Products

    Institute of Scientific and Technical Information of China (English)

    2004-01-01

    @@ Reporters learned from the Certification and Accreditation Administration of China(CNCA)that burglar-proof door became the first batch of voluntary certification product in public security products.China has formally initiated voluntary certification of public security products.

  1. Voluntary sterilization in Serbia: Unmet need?

    Directory of Open Access Journals (Sweden)

    Rašević Mirjana M.

    2002-01-01

    Full Text Available Is voluntary sterilization as a birth control method accepted in Serbia? This is certainly a question that is being imposed for research, regardless of the fact that voluntary sterilization is neither accessible nor promoted. Most importantly because there is no understanding in the social nor political sphere for legalization of voluntary sterilization as a form of birth control, apart from the clear necessity for this, first, step. They are: the recognition that voluntary sterilization is an efficient and safe birth control method, respectability of basic human as well as sexual and reproductive rights, spreading of sterilization as a form of birth control among population of both developed and developing countries and an epidemic diffusion of repeated induced abortions in Serbia. Thus individual recognition of the advantages of relying on voluntary sterilization, in a non-encouraging atmosphere, certainly represents one more argument to enable couples to prevent conception by sterilization. Since it was impossible to carry out a representative research among the population of men and women who are at risk for conception, an attempt was made to obtain a reply to the set question among women who decided to induce abortion. It was done out of at least two reasons. The first being that women with induced abortion in their reproductive history were the target group for voluntary sterilization. The second reason was based on the assumption that bringing a decision on induced abortion is preceded by the reconsideration of an earlier adopted strategy regarding children, giving birth and contraception and thus its rational component is revealed more and therefore more easily measurable. The research was carried out in the University Clinic of Obstetrics and Gynecology 'Narodni front' in Belgrade from January 21st o March 1st 2002, and included 296 women. By comparing the social and demographic characteristics of the female respondents, as well as

  2. Comprehensive proteomic analysis of bovine spermatozoa of varying fertility rates and identification of biomarkers associated with fertility

    Directory of Open Access Journals (Sweden)

    Kaya Abdullah

    2008-02-01

    Full Text Available Abstract Background Male infertility is a major problem for mammalian reproduction. However, molecular details including the underlying mechanisms of male fertility are still not known. A thorough understanding of these mechanisms is essential for obtaining consistently high reproductive efficiency and to ensure lower cost and time-loss by breeder. Results Using high and low fertility bull spermatozoa, here we employed differential detergent fractionation multidimensional protein identification technology (DDF-Mud PIT and identified 125 putative biomarkers of fertility. We next used quantitative Systems Biology modeling and canonical protein interaction pathways and networks to show that high fertility spermatozoa differ from low fertility spermatozoa in four main ways. Compared to sperm from low fertility bulls, sperm from high fertility bulls have higher expression of proteins involved in: energy metabolism, cell communication, spermatogenesis, and cell motility. Our data also suggests a hypothesis that low fertility sperm DNA integrity may be compromised because cell cycle: G2/M DNA damage checkpoint regulation was most significant signaling pathway identified in low fertility spermatozoa. Conclusion This is the first comprehensive description of the bovine spermatozoa proteome. Comparative proteomic analysis of high fertility and low fertility bulls, in the context of protein interaction networks identified putative molecular markers associated with high fertility phenotype.

  3. Effects of transcranial magnetic stimulation during voluntary and non-voluntary stepping movements in humans.

    Science.gov (United States)

    Solopova, I A; Selionov, V A; Kazennikov, O V; Ivanenko, Y P

    2014-09-05

    Here, we compared motor evoked potentials (MEP) in response to transcranial magnetic stimulation of the motor cortex and the H-reflex during voluntary and vibration-induced air-stepping movements in humans. Both the MEPs (in mm biceps femoris, rectus femoris and tibialis anterior) and H-reflex (in m soleus) were significantly smaller during vibration-induced cyclic leg movements at matched amplitudes of angular motion and muscle activity. These findings highlight differences between voluntary and non-voluntary activation of the spinal pattern generator circuitry in humans, presumably due to an extra facilitatory effect of voluntary control/triggering of stepping on spinal motoneurons and interneurons. The results support the idea of active engagement of supraspinal motor areas in developing central pattern generator-modulating therapies. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

  4. Fertilization in northern forests

    DEFF Research Database (Denmark)

    Hedwall, Per Ola; Gong, Peichen; Ingerslev, Morten

    2014-01-01

    resources into food, health and industrial products and energy. Fertilization in Sweden and Finland is currently practiced by extensive fertilization regimens where nitrogen fertilizers are applied once, or up to three times, during a rotation period, mainly in mature forest. This type of fertilization......Forests of northern ecosystems respond slowly to management activities and the possibilities to increase the growth in a short-term perspective and meet swift increases in society's demand for biomass are small. An exception among the silvicultural measures is fertilization which can be applied...... in combination with present management systems and, almost instantly, enhances forest productivity. There may, however, be both economic and environmental constraints to large-scale applications of fertilizers in forest. Here we review the literature concerning biomass production of forests under different...

  5. Fertility Preservation for Female

    Institute of Scientific and Technical Information of China (English)

    Jack Huang; Seang Lin Tan; Ri-Cheng Chian

    2006-01-01

    Preservation of female fertility is an important issue today. However, there are few effective clinical options for preserving female fertility. Firstly, conventional in vitro fertilization (IVF) followed by embryo cryopreservation is an accepted procedure but is not applicable to all women. Embryo freezing is suitable only for women with a male partner and may not be acceptable to some patients due to moral and religious reasons. Ovarian tissue freezing is another option of female fertility preservation but is an invasive procedure and the efficacy of this technique remains to be determined.Oocyte cryopreservation is also method for fertility preservation. Egg freezing is minimally invasive and can avoid the ethical and moral concerns related to cryopreservation of embryos. However, conventional slow freezing/rapid thawing methods are associated with low survival of oocytes. Recent development in vitrification of oocytes appears promising. Therefore, vitrification of unfertilized eggs may be a novel method to preserve female fertility.

  6. Moving from voluntary euthanasia to non-voluntary euthanasia: equality and compassion.

    Science.gov (United States)

    Amaraskekara, Kumar; Bagaric, Mirko

    2004-09-01

    The recent Dutch law legalising active voluntary euthanasia will reignite the euthanasia debate. An illuminating method for evaluating the moral status of a practice is to follow the implications of the practice to its logical conclusion. The argument for compassion is one of the central arguments in favour of voluntary active euthanasia. This argument applies perhaps even more forcefully in relation to incompetent patients. If active voluntary euthanasia is legalised, arguments based on compassion and equality will be directed towards legalising active non-voluntary euthanasia in order to make accelerated termination of death available also to the incompetent. The removal of discrimination against the incompetent has the potential to become as potent a catch-cry as the right to die. However, the legalisation of non-voluntary euthanasia is undesirable. A review of the relevant authorities reveals that there is no coherent and workable "best interests" test which can be invoked to decide whether an incompetent patient is better off dead. This provides a strong reason for not stepping onto the slippery path of permitting active voluntary euthanasia.

  7. 5 CFR 919.1020 - Voluntary exclusion or voluntarily excluded.

    Science.gov (United States)

    2010-01-01

    ... 5 Administrative Personnel 2 2010-01-01 2010-01-01 false Voluntary exclusion or voluntarily excluded. 919.1020 Section 919.1020 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT (CONTINUED...) Definitions § 919.1020 Voluntary exclusion or voluntarily excluded. (a) Voluntary exclusion means a person's...

  8. 37 CFR 351.2 - Voluntary negotiation period; settlement.

    Science.gov (United States)

    2010-07-01

    ... 37 Patents, Trademarks, and Copyrights 1 2010-07-01 2010-07-01 false Voluntary negotiation period... CONGRESS COPYRIGHT ROYALTY JUDGES RULES AND PROCEDURES PROCEEDINGS § 351.2 Voluntary negotiation period..., the Copyright Royalty Judges will announce the beginning of a voluntary negotiation period and...

  9. 15 CFR 12.3 - Development of voluntary product standards.

    Science.gov (United States)

    2010-01-01

    ... 15 Commerce and Foreign Trade 1 2010-01-01 2010-01-01 false Development of voluntary product... AND LABELING § 12.3 Development of voluntary product standards. (a) Invitation to participate in the development of a voluntary product standard. Whenever the Secretary publishes a final determination of...

  10. Does lower dose of long-acting triptorelin maintain pituitary suppression and produce good live birth rate in long down-regulation protocol for in-vitro fertilization?

    Science.gov (United States)

    Chen, Xin; Feng, Shu-xian; Guo, Ping-ping; He, Yu-xia; Liu, Yu-dong; Ye, De-sheng; Chen, Shi-ling

    2016-04-01

    The effects of pituitary suppression with one-third depot of long-acting gonadotropin-releasing hormone (GnRH) agonist in GnRH agonist long protocol for in vitro fertilization (IVF)/intracytoplasmic sperm injection (ICSI) were investigated. A retrospective cohort study was performed on 3186 cycles undergoing IVF/ICSI with GnRH agonist long protocol in a university-affiliated infertility center. The pituitary was suppressed with depot triptorelin of 1.25 mg or 1.875 mg. There was no significant difference in live birth rate between 1.25 mg triptorelin group and 1.875 mg triptorelin group (41.2% vs. 43.7%). The mean luteinizing hormone (LH) level on follicle-stimulating hormone (FSH) starting day was significantly higher in 1.25 mg triptorelin group. The mean LH level on the day of human chorionic gonadotrophin (hCG) administration was slightly but statistically higher in 1.25 mg triptorelin group. There was no significant difference in the total FSH dose between the two groups. The number of retrieved oocytes was slightly but statistically less in 1.25 mg triptorelin group than in 1.875 mg triptorelin group (12.90±5.82 vs. 13.52±6.97). There was no significant difference in clinical pregnancy rate between the two groups (50.5% vs. 54.5%). It was suggested that one-third depot triptorelin can achieve satisfactory pituitary suppression and produce good live birth rates in a long protocol for IVF/ICSI.

  11. Fertilization in echinoderms.

    Science.gov (United States)

    Santella, Luigia; Vasilev, Filip; Chun, Jong T

    2012-08-31

    For more than 150 years, echinoderm eggs have served as overly favored experimental model systems in which to study fertilization. Sea urchin and starfish belong to the same phylum and thus share many similarities in their fertilization patterns. However, several subtle but fundamental differences do exist in the fertilization of sea urchin and starfish, reflecting their phylogenetic bifurcation approximately 500 million years ago. In this article we review some of the seminal and recent findings that feature similarities and differences in sea urchin and starfish at fertilization.

  12. Evolutionary approach to understand human low fertility phenomenon

    CERN Document Server

    Černák, Jozef

    2016-01-01

    Is it possible to turn the low fertility? We think that more radical change of the global economy is needed that will stimulate series of self-regulation processes and evolution toward the safe fertility. Proposed changes should stimulate more uniform spatial distribution of production and wealth usage, increase in a number of self-sufficient territories, decrease of labor mobility and social mobility and careful consideration of a biological nature of fertility in economical or social actions.

  13. Fertilizer Use and Water Quality.

    Science.gov (United States)

    Reneau, Fred; And Others

    This booklet presents informative materials on fertilizer use and water quality, specifically in regard to environmental pollution and protection in Illinois. The five chapters cover these topics: Fertilizer and Water Quality, Fertilizer Use, Fertilizers and the Environment, Safety Practices, and Fertilizer Management Practices. Key questions are…

  14. Fertilizer Use and Water Quality.

    Science.gov (United States)

    Reneau, Fred; And Others

    This booklet presents informative materials on fertilizer use and water quality, specifically in regard to environmental pollution and protection in Illinois. The five chapters cover these topics: Fertilizer and Water Quality, Fertilizer Use, Fertilizers and the Environment, Safety Practices, and Fertilizer Management Practices. Key questions are…

  15. Burrowing as a novel voluntary strength training method for mice : A comparison of various voluntary strength or resistance exercise methods

    NARCIS (Netherlands)

    Roemers, P; Mazzola, P N; De Deyn, P P; Bossers, W J; van Heuvelen, M J G; van der Zee, E A

    2017-01-01

    BACKGROUND: Voluntary strength training methods for rodents are necessary to investigate the effects of strength training on cognition and the brain. However, few voluntary methods are available. NEW METHOD: The current study tested functional and muscular effects of two novel voluntary strength

  16. Correlations in fertility across generations: can low fertility persist?

    Science.gov (United States)

    Kolk, Martin; Cownden, Daniel; Enquist, Magnus

    2014-03-22

    Correlations in family size across generations could have a major influence on human population size in the future. Empirical studies have shown that the associations between the fertility of parents and the fertility of children are substantial and growing over time. Despite their potential long-term consequences, intergenerational fertility correlations have largely been ignored by researchers. We present a model of the fertility transition as a cultural process acting on new lifestyles associated with fertility. Differences in parental and social influences on the acquisition of these lifestyles result in intergenerational correlations in fertility. We show different scenarios for future population size based on models that disregard intergenerational correlations in fertility, models with fertility correlations and a single lifestyle, and models with fertility correlations and multiple lifestyles. We show that intergenerational fertility correlations will result in an increase in fertility over time. However, present low-fertility levels may persist if the rapid introduction of new cultural lifestyles continues into the future.

  17. Evaluation of two dairy herd reproductive performance indicators that are adjusted for voluntary waiting period

    Directory of Open Access Journals (Sweden)

    Löf Emma

    2012-01-01

    Full Text Available Abstract Background Overall reproductive performance of dairy herds is monitored by various indicators. Most of them do not consider all eligible animals and do not consider different management strategies at farm level. This problem can be alleviated by measuring the proportion of pregnant cows by specific intervals after their calving date or after a fixed time period, such as the voluntary waiting period. The aim of this study was to evaluate two reproductive performance indicators that consider the voluntary waiting period at the herd. The two indicators were: percentage of pregnant cows in the herd after the voluntary waiting period plus 30 days (PV30 and percentage of inseminated cows in the herd after the voluntary waiting period plus 30 days (IV30. We wanted to assess how PV30 and IV30 perform in a simulation of herds with different reproductive management and physiology and to compare them to indicators of reproductive performance that do not consider the herd voluntary waiting period. Methods To evaluate the reproductive indicators we used the SimHerd-program, a stochastic simulation model, and 18 scenarios were simulated. The scenarios were designed by altering the reproductive management efficiency and the status of reproductive physiology of the herd. Logistic regression models, together with receiver operating characteristics (ROC, were used to examine how well the reproductive performance indicators could discriminate between herds of different levels of reproductive management efficiency or reproductive physiology. Results The logistic regression models with the ROC analysis showed that IV30 was the indicator that best discriminated between different levels of management efficiency followed by PV30, calving interval, 200-days not-in calf-rate (NotIC200, in calf rate at100-days (IC100 and a fertility index. For reproductive physiology the ROC analysis showed that the fertility index was the indicator that best discriminated

  18. Voluntary reporting of greenhouse gases 1997

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-05-01

    The Voluntary Reporting of Greenhouse Gases Program, required by Section 1605(b) of the Energy Policy Act of 1992, records the results of voluntary measures to reduce, avoid, or sequester greenhouse gas emissions. In 1998, 156 US companies and other organizations reported to the Energy information Administration that, during 1997, they had achieved greenhouse gas emission reductions and carbon sequestration equivalent to 166 million tons of carbon dioxide, or about 2.5% of total US emissions for the year. For the 1,229 emission reduction projects reported, reductions usually were measured by comparing an estimate of actual emissions with an estimate of what emissions would have been had the project not been implemented.

  19. Voluntary simulation workshops in nursing education

    DEFF Research Database (Denmark)

    Selberg, Hanne; Nielsen, Mette Elisabeth

    2012-01-01

    Voluntary simulation workshops in nursing education Hanne Selberg1, Mette Elisabeth Nielsen1, Mette Wenzel Horsted2, Karen Bertelsen2, Marianne Linnet Rasmussen2,Rikke Lohmann Panton3, Copenhagen, Mette Kjeldal Jensen4 Background Changes in nursing education in Denmark towards an academic approach...... with more theory and less practical training have resulted in discussions regarding the lack of practical skills amongst novice nurses. A Danish study of students’ drop-out from the nursing education indicates that difficulties in combining theory and practice are one of the motivating factors behind...... the students’ decision to drop out (Jensen et al. 2008). Within the past year our faculty has conducted several projects with the aim of integrating simulation into the curriculum. Furthermore, voluntary simulation workshop has been carried out as an additional offer in the nursing education. The purpose has...

  20. The Political Importance of Voluntary Work.

    Science.gov (United States)

    Kunneman, Harry

    This paper aims to develop a complex articulation of the civic meaningfulness of voluntary work that clarifies its political importance as a countervailing narrative pointing beyond dominant neoliberal and consumptive articulations of a good life. To start with, it sketches a hermeneutic perspective on civic meaningfulness based on the work of Paul Ricoeur. Subsequently, it introduces the ideas of 'ethical complexity', 'epistemological complexity' and 'diapoiesis', building on insights from critical complexity thinking and relational biology. It argues that these notions can provide a bridge between hermeneutic perspectives on meaning and values, on the one hand, and questions of meaning and values on the level of scientific and technological developments and within professional organizations, on the other. Thus a broader, more complex picture emerges of the civic meaningfulness of voluntary work in our times.

  1. Voluntary Management Earnings Forecasts and Discretionary Accruals

    DEFF Research Database (Denmark)

    Gramlich, Jeffrey; Sørensen, Ole Vagn

    2004-01-01

    This paper seeks to determine whether Danish managers exercise discretionary accruals to reach earnings forecast targets they voluntarily specify in conjunction with initial public offerings (IPOs). Because the Danish accounting and legal environment is more permissive than the US, we use Denmark...... as a natural laboratory for learning how business would occur without strict rules, enforcement and sanctions. Danish managers often volunteer pro forma financial statements for results that are expected to occur subsequent to the IPO. We examine a sample of 58 Danish firms that issue voluntary management...... earnings forecasts in connection with IPOs that occur between 1984 and 1996. The evidence we uncover strongly suggests that pre-managed earnings are adjusted toward these targets. In contrast with Kasznik's (1999 Kasznik, R. (1999). On the association between voluntary disclosure and earnings management...

  2. Family systems and fertility

    NARCIS (Netherlands)

    Moenkediek, Bastian

    2016-01-01

    This thesis studies the role of regional family organization principles, so called family systems, for explaining fertility behaviours in different parts of Europe. Studying family systems and its impact on fertility is important, because many aspects of societal life, such as the organization of we

  3. Factors that affect voluntary vaccination of children in Japan.

    Science.gov (United States)

    Shono, Aiko; Kondo, Masahide

    2015-03-10

    Some important vaccinations are not included in the routine childhood immunization schedule in Japan. Voluntary vaccinations are usually paid as an out-of-pocket expense. Low voluntary vaccination coverage rates and high target disease incidence are assumed to be a consequence of voluntary vaccination. Therefore, this study aimed to explore factors associated with voluntary vaccination patterns in children. We conducted an online survey of 1243 mothers from a registered survey panel who had at least one child 2 months to vaccination mainly correlated positively with annual household income and mothers' positive opinions about voluntary vaccinations, but negatively with number of children. Financial support, especially for low income households and households with more than one child, may motivate parents to vaccinate their children. Communication is also an important issue. More opportunities for education and information about voluntary vaccinations should be provided to mothers without distinguishing between voluntary and routine vaccination.

  4. Fertility decline in Paraguay.

    Science.gov (United States)

    Ishida, Kanako; Stupp, Paul; Melian, Mercedes

    2009-09-01

    Recent reproductive health surveys show that the fertility rate in Paraguay decreased precipitously from 4.3 lifetime births per woman in 1995-98 to 2.9 births in 2001-04. In this study, we establish data consistency between the 1998 and 2004 surveys by comparing a series of cohort-specific period rates and use the Bongaarts framework of proximate determinants of fertility to demonstrate that an increase in the contraceptive prevalence rate (CPR) between 1998 and 2004 fully accounts for the fertility decline. Decomposition of rates shows that changes in group-specific CPRs explain a greater proportion of the change in the overall CPR than do changes in population composition by educational attainment, urban residence, region, and language spoken at home. Finally, we show that younger cohorts of women in 2004 reported ideal completed fertility desires of less than 2.9 births, suggesting that the fertility rate is likely to continue to decrease.

  5. [Socioeconomic variables and fertility].

    Science.gov (United States)

    Arguello, O

    1980-08-01

    While making comparative analyses of data collected by the World Fertility Survey regarding Latin America, a group of investigators of CELADE (Centro Latinoamericano de Demografia) realized that the selection of economic variables for the study of fertility had serious limitations. Such limitations did not allow the elaboration of a theory which took into account the complicated process of fertility, in all its socioeconomic, cultural, and psychological manifestations. Thus, this paper intends to lay the theoretical basis for the selection of all relevant variables, distinguishing, for example, the average fertility of women according to area of residence, place of early socialization, migrant status, social status, occupation of husband, level of instruction, occupation, and all changes in occupational activities of women in fertile age.

  6. Mitigating greenhouse gas emissions: Voluntary reporting

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-10-01

    The Voluntary Reporting Program, developed pursuant to Section 1605(b) of the Energy Policy Act of 1992, permits corporations, government agencies, households, and voluntary organizations to report on their emissions of greenhouse gases, and on actions taken that have reduced or avoided emissions or sequestered carbon, to the Energy Information Administration (EIA). This, the second annual report of the Voluntary Reporting Program, describes information provided by the participating organizations on their aggregate emissions and emissions reductions, as well as their emissions reduction or avoidance projects, through 1995. This information has been compiled into a database that includes reports from 142 organizations and descriptions of 967 projects that either reduced greenhouse gas emissions or sequestered carbon. Fifty-one reporters also provided estimates of emissions, and emissions reductions achieved, for their entire organizations. The projects described actions taken to reduce emissions of carbon dioxide from energy production and use; to reduce methane and nitrous oxide emissions from energy use, waste management, and agricultural processes; to reduce emissions of halocarbons, such as CFCs and their replacements; and to increase carbon sequestration.

  7. Voluntary Green Power Market Forecast through 2015

    Energy Technology Data Exchange (ETDEWEB)

    Bird, L.; Holt, E.; Sumner, J.; Kreycik, C.

    2010-05-01

    Various factors influence the development of the voluntary 'green' power market--the market in which consumers purchase or produce power from non-polluting, renewable energy sources. These factors include climate policies, renewable portfolio standards (RPS), renewable energy prices, consumers' interest in purchasing green power, and utilities' interest in promoting existing programs and in offering new green options. This report presents estimates of voluntary market demand for green power through 2015 that were made using historical data and three scenarios: low-growth, high-growth, and negative-policy impacts. The resulting forecast projects the total voluntary demand for renewable energy in 2015 to range from 63 million MWh annually in the low case scenario to 157 million MWh annually in the high case scenario, representing an approximately 2.5-fold difference. The negative-policy impacts scenario reflects a market size of 24 million MWh. Several key uncertainties affect the results of this forecast, including uncertainties related to growth assumptions, the impacts that policy may have on the market, the price and competitiveness of renewable generation, and the level of interest that utilities have in offering and promoting green power products.

  8. Modelisation of the regulation of protein synthesis following fertilization in sea urchin shows requirement of two processes: a destabilization of eIF4E:4E-BP complex and a great stimulation of the 4E-BP-degradation mechanism, both rapamycin-sensitive.

    Directory of Open Access Journals (Sweden)

    Sébastien eLaurent

    2014-05-01

    Full Text Available Fertilization of sea urchin eggs involves an increase in protein synthesis associated with a decrease in the amount of the translation initiation inhibitor 4E-BP. A highly simple reaction model for the regulation of protein synthesis was built and was used to simulate the physiological changes in the total 4E-BP amount observed during time after fertilization. Our study evidenced that two changes occurring at fertilization are necessary to fit with experimental data. The first change was an 8 fold increase in the dissociation parameter (koff1 of the eIF4E:4E-BP complex. The second was an important 32.5 fold activation of the degradation mechanism of the protein 4E-BP. Additionally, the changes in both processes should occur in five minutes time interval post fertilization. To validate the model, we checked that the kinetic of the predicted 4.2 fold increase of eIF4E:eIF4G complex concentration at fertilization matched the increase of protein synthesis experimentally observed after fertilization (6.6 fold, SD=2.3, n=8. The minimal model was also used to simulate changes observed after fertilization in the presence of rapamycin, a FRAP/mTOR inhibitor. The model showed that the eIF4E:4E-BP complex destabilization was impacted and, surprisingly, that the mechanism of 4E-BP degradation was also strongly affected, therefore suggesting that both processes are controlled by the protein kinase FRAP/mTOR.

  9. Meticulous Overview on the Controlled Release Fertilizers

    Directory of Open Access Journals (Sweden)

    Siafu Ibahati Sempeho

    2014-01-01

    Full Text Available Owing to the high demand for fertilizer formulations that will exhaust the possibilities of nutrient use efficiency (NUE, regulate fertilizer consumption, and lessen agrophysicochemical properties and environmental adverse effects instigated by conventional nutrient supply to crops, this review recapitulates controlled release fertilizers (CRFs as a cutting-edge and safe way to supply crops’ nutrients over the conventional ways. Essentially, CRFs entail fertilizer particles intercalated within excipients aiming at reducing the frequency of fertilizer application thereby abating potential adverse effects linked with conventional fertilizer use. Application of nanotechnology and materials engineering in agriculture particularly in the design of CRFs, the distinctions and classification of CRFs, and the economical, agronomical, and environmental aspects of CRFs has been revised putting into account the development and synthesis of CRFs, laboratory CRFs syntheses and testing, and both linear and sigmoid release features of CRF formulations. Methodical account on the mechanism of nutrient release centring on the empirical and mechanistic approaches of predicting nutrient release is given in view of selected mathematical models. Compositions and laboratory preparations of CRFs basing on in situ and graft polymerization are provided alongside the physical methods used in CRFs encapsulation, with an emphasis on the natural polymers, modified clays, and superabsorbent nanocomposite excipients.

  10. Novel Role for p110β PI 3-Kinase in Male Fertility through Regulation of Androgen Receptor Activity in Sertoli Cells

    Science.gov (United States)

    Guillermet-Guibert, Julie; Smith, Lee B.; Halet, Guillaume; Whitehead, Maria A.; Pearce, Wayne; Rebourcet, Diane; León, Kelly; Crépieux, Pascale; Nock, Gemma; Strömstedt, Maria; Enerback, Malin; Chelala, Claude; Graupera, Mariona; Carroll, John; Cosulich, Sabina; Saunders, Philippa T. K.; Huhtaniemi, Ilpo; Vanhaesebroeck, Bart

    2015-01-01

    The organismal roles of the ubiquitously expressed class I PI3K isoform p110β remain largely unknown. Using a new kinase-dead knockin mouse model that mimics constitutive pharmacological inactivation of p110β, we document that full inactivation of p110β leads to embryonic lethality in a substantial fraction of mice. Interestingly, the homozygous p110β kinase-dead mice that survive into adulthood (maximum ~26% on a mixed genetic background) have no apparent phenotypes, other than subfertility in females and complete infertility in males. Systemic inhibition of p110β results in a highly specific blockade in the maturation of spermatogonia to spermatocytes. p110β was previously suggested to signal downstream of the c-kit tyrosine kinase receptor in germ cells to regulate their proliferation and survival. We now report that p110β also plays a germ cell-extrinsic role in the Sertoli cells (SCs) that support the developing sperm, with p110β inactivation dampening expression of the SC-specific Androgen Receptor (AR) target gene Rhox5, a homeobox gene critical for spermatogenesis. All extragonadal androgen-dependent functions remain unaffected by global p110β inactivation. In line with a crucial role for p110β in SCs, selective inactivation of p110β in these cells results in male infertility. Our study is the first documentation of the involvement of a signalling enzyme, PI3K, in the regulation of AR activity during spermatogenesis. This developmental pathway may become active in prostate cancer where p110β and AR have previously been reported to functionally interact. PMID:26132308

  11. Novel Role for p110β PI 3-Kinase in Male Fertility through Regulation of Androgen Receptor Activity in Sertoli Cells.

    Directory of Open Access Journals (Sweden)

    Julie Guillermet-Guibert

    2015-07-01

    Full Text Available The organismal roles of the ubiquitously expressed class I PI3K isoform p110β remain largely unknown. Using a new kinase-dead knockin mouse model that mimics constitutive pharmacological inactivation of p110β, we document that full inactivation of p110β leads to embryonic lethality in a substantial fraction of mice. Interestingly, the homozygous p110β kinase-dead mice that survive into adulthood (maximum ~26% on a mixed genetic background have no apparent phenotypes, other than subfertility in females and complete infertility in males. Systemic inhibition of p110β results in a highly specific blockade in the maturation of spermatogonia to spermatocytes. p110β was previously suggested to signal downstream of the c-kit tyrosine kinase receptor in germ cells to regulate their proliferation and survival. We now report that p110β also plays a germ cell-extrinsic role in the Sertoli cells (SCs that support the developing sperm, with p110β inactivation dampening expression of the SC-specific Androgen Receptor (AR target gene Rhox5, a homeobox gene critical for spermatogenesis. All extragonadal androgen-dependent functions remain unaffected by global p110β inactivation. In line with a crucial role for p110β in SCs, selective inactivation of p110β in these cells results in male infertility. Our study is the first documentation of the involvement of a signalling enzyme, PI3K, in the regulation of AR activity during spermatogenesis. This developmental pathway may become active in prostate cancer where p110β and AR have previously been reported to functionally interact.

  12. Bottom-"wide" Approach to Climate Change - Typology and Analysis on Climate Vulnerability Reduction through Voluntary Actions

    Directory of Open Access Journals (Sweden)

    Kiyoto Yamaura

    2013-07-01

    Full Text Available Climate change risk is mostly and often unfairly cast upon those who are vulnerable. As one of the effective and spreadable means in reducing human vulnerability to climate change, this paper and its findings address the role, strength and limitations of voluntary actions. Through an extensive review of various climate change literature, projects and interviews among practitioners, the authors looked at thetypes of interventions and results that voluntary actions have achieved. The paperintroducesvarious types of voluntary activities such as awareness raising, community mobilization and empowerment, community-based adaptation and mitigation, and voluntary environmental regulations and schemes. Such bottom-"wide" approach to climate change is closely linked with civil environmentalism with broad focus and also scientifically strengthened by its engagement with civic science. It urges shifting the mind-set of international development agencies to flexibly accommodate and maximize the potential of voluntary, bottom-wide actions in combating climate change. Finally, the paper lists out pieces of recommendation to further improve and fully utilize voluntary actions in reducing vulnerabilityon the ground, by emphasizing long-term orientation, capacity development, monitoring and evaluation and building partnerships at the local level.

  13. SEWAGE SLUDGE AS AN INGREDIENT IN FERTILIZERS AND SOIL SUBSTITUTES

    Directory of Open Access Journals (Sweden)

    Anna Grobelak

    2016-06-01

    Full Text Available In Poland, sludge management especially in medium and small sewage treatment plants is still a significant problem. According to data from the Central Statistical Office and the report on the implementation of the National Urban Wastewater Treatment Program (in polish KPOŚK land application of sewage sludge remains one of the main methods, although there has been considerable interest known: 'application for other purposes ", where the preparation of composts and fertilizers is included. The use of fertilizer produced from sewage sludge (compost, granules, organic and mineral fertilizers, is regulated by the Act on fertilizers and fertilization, and the relevant implementing rules. For example, they define the test procedure (concerning the quality of fertilizers to enable appropriate permissions to market this type of fertilizers. There is still only several technologies existing on the Polish market dedicated to production of fertilizers in advanced technologies of sewage sludge treatment. Usually the treatment plants are trying to obtain the necessary certificates for generated fertilizers (including composts, or soils substitutes. The advantages of these technologies should be no doubt: the loss of waste status, ability to store the fertilizer and unlimited transportation between areas, sanitization of the product (as a result of the use of calcium or sulfur compounds or temperature should be an alternative for drying technology. While the disadvantages are primarily the investment costs and time consuming certification procedures. However, these solutions enable to maintain the organic matter and phosphorus as well as greater control over possible pollution introduced into the soil.

  14. The Emotional Response to Everyday Involuntary and Voluntary Memories in Dysphoria and Non-Dysphoria

    DEFF Research Database (Denmark)

    del Palacio Gonzalez, Adriana; Watson, Lynn; Berntsen, Dorthe

    Retrieving personal memories may cause emotional reactions and thus a need for emotion regulation. Past research indicates that involuntary memories have a greater effect on mood that the voluntary counterparts. However, different dimensions of the emotional response (i.e., intensity and regulation......-depressed individuals completed a structured memory diary where the intensity of fear, sadness, happiness, and anger, as well as the employment of emotion regulation strategies (brooding, memory suppression, emotional suppression, and reflection) was recorded upon the retrieval of everyday autobiographical memories...

  15. 49 CFR 1300.5 - Additional publication requirement for agricultural products and fertilizer.

    Science.gov (United States)

    2010-10-01

    ... agricultural products and fertilizer. 1300.5 Section 1300.5 Transportation Other Regulations Relating to... fertilizer. (a) With respect to transportation of agricultural products (including grain, as defined in 7 U.S.C. 75, and all products thereof) and fertilizer, a rail carrier shall publish, make available,...

  16. Study of Dynamics of Floodwater Nitrogen and Regulation of Its Runoff Loss in Paddy Field-Based Two-Cropping Rice with Urea and Controlled Release Nitrogen Fertilizer Application

    Institute of Scientific and Technical Information of China (English)

    JI Xiong-hui; ZHENG Sheng-xian; LU Yan-hong; LIAO Yu-lin

    2007-01-01

    The article deals with the effects of urea and controlled release nitrogen fertilizer (CRNF) on dynamics of pH, electronic conductivity (EC), total nitrogen (TN), NH4+-N and NO3--N in floodwater, and the regulation of runoff TN loss from paddy field-based two-cropping rice in Dongting Lake, China, and probes the best fertilization management for controlling N loss. Studies were conducted through modeling alluvial sandy loamy paddy soil (ASP) and purple calcareous clayey paddy soil (PCP) using lysimeter, following the sequence of the soil profiles identified by investigating soil profile. After application of urea in paddy field-based two-cropping rice, TN and NH4+-N concentrations in floodwater reached peak on the 1st and the 3rd day, respectively, and then decreased rapidly over time; all the floodwater NO3--N concentrations were very low; the pH of floodwater gradually rose in case of early rice within 15 d (late rice within 3 d) after application of urea,and EC remained consistent with the dynamics of NH4+-N. The applied CRNF, especially 70% CRNF, led to significantly lower floodwater TN and NH4+ concentrations, pH, and EC values compared with urea within 15 d after application. The monitoring result for N loss due to natural rainfall runoff indicated that the amount of TN lost in runoff from paddy fieldbased two-cropping rice with urea application in Dongting Lake area was 7.47 kg ha-1, which accounted for 2.49% of ureaN applied, and that with CRNF and 70% CRNF application decreased 24.5 and 27.2% compared with urea application,respectively. The two runoff events, which occurred within 20 d after application, contributed significantly to TN loss from paddy field. TN loss due to the two runoffs in urea, CRNF, and 70% CRNF treatments accounted for 72, 70, and 58% of the total TN loss due to runoff over the whole rice growth season, respectively. And the TN loss in these two CRNF treatments due to the first run-off event at the 10th day after application to early

  17. Association between firm characteristics and corporate voluntary disclosure: Evidence from Turkish listed companies

    Directory of Open Access Journals (Sweden)

    Ali Uyar

    2013-12-01

    Full Text Available Purpose: This paper empirically investigates the factors that impact voluntary information disclosure level of Turkish manufacturing companies listed in the Istanbul Stock Exchange (ISE. Design/methodology/approach: The methodology of the study is content analysis of annual reports of the corporations listed on the ISE for the year 2010. Findings: The findings provide evidence of a positive association between voluntary information disclosure level and the variables such as firm size, auditing firm size, proportion of independent directors on the board, institutional/corporate ownership, and corporate governance. However, leverage and ownership diffusion were found to have negative significant association with the extent of voluntary disclosure. The remaining variables, namely, profitability, listing age, and board size were found to be insignificant. Research limitations/implications: Since this study was conducted solely on listed manufacturing companies, the results may not be generalizable to non-listed and non-manufacturing industries. The study has some implications for firms, auditors, investors, and regulators. All these parties play an important role in improving the transparency and disclosure practices of corporations. Originality/value: We extend previous research on the determinants of voluntary information disclosure in the emerging market context.

  18. Optimizing Natural Fertility

    Science.gov (United States)

    ... heavy alcohol consumption (> 2 drinks per day), heavy caffeine consumption, and the use of recreational drugs such as marijuana have all been associated with reduced fertility. Therefore, women (and ... alcohol and caffeine use, and avoid smoking and all recreational drugs ...

  19. Commercial Nitrogen Fertilizer Purchased

    Data.gov (United States)

    U.S. Environmental Protection Agency — Amounts of fertilizer nitrogen (N) purchased by states in individual years 2003, 2005, 2007, 2009 and 2011, and the % change in average amounts purchased per year...

  20. Chapter VII. Predicting Fertility

    Science.gov (United States)

    Section 2. Visual and Microscopic Approaches for Differentiating Unfertilized Germinal Discs and Early dead Embryos from Pre-Incubated Blastoderms Section 3. Predicting the Duration of fertility by Counting Sperm in the Outer Perivitelline Layer of Laid Eggs...

  1. Cancer and fertility preservation

    DEFF Research Database (Denmark)

    Lambertini, Matteo; Del Mastro, Lucia; Pescio, Maria C

    2016-01-01

    cryopreservation and embryo/oocyte cryopreservation are standard strategies for fertility preservations in male and female patients, respectively; other strategies (e.g. pharmacological protection of the gonads and gonadal tissue cryopreservation) are considered experimental techniques. However, since then, new......In the last years, thanks to the improvement in the prognosis of cancer patients, a growing attention has been given to the fertility issues. International guidelines on fertility preservation in cancer patients recommend that physicians discuss, as early as possible, with all patients...... of reproductive age their risk of infertility from the disease and/or treatment and their interest in having children after cancer, and help with informed fertility preservation decisions. As recommended by the American Society of Clinical Oncology and the European Society for Medical Oncology, sperm...

  2. Commercial Phosporus Fertilizer Purchased

    Data.gov (United States)

    U.S. Environmental Protection Agency — Amounts of fertilizer P2O5 purchased by states in individual years 2003, 2005, 2007, 2009 and 2011, and the % change in average amounts purchased per year from...

  3. The parallel programming of voluntary and reflexive saccades.

    Science.gov (United States)

    Walker, Robin; McSorley, Eugene

    2006-06-01

    A novel two-step paradigm was used to investigate the parallel programming of consecutive, stimulus-elicited ('reflexive') and endogenous ('voluntary') saccades. The mean latency of voluntary saccades, made following the first reflexive saccades in two-step conditions, was significantly reduced compared to that of voluntary saccades made in the single-step control trials. The latency of the first reflexive saccades was modulated by the requirement to make a second saccade: first saccade latency increased when a second voluntary saccade was required in the opposite direction to the first saccade, and decreased when a second saccade was required in the same direction as the first reflexive saccade. A second experiment confirmed the basic effect and also showed that a second reflexive saccade may be programmed in parallel with a first voluntary saccade. The results support the view that voluntary and reflexive saccades can be programmed in parallel on a common motor map.

  4. Voluntary energy optimisation - Taking responsibility; Verantwortungsvoll

    Energy Technology Data Exchange (ETDEWEB)

    Baettig, I.

    2006-07-01

    This interview with Konrad Kyburz, CEO of a printing shop in Dielsdorf, Switzerland, discusses how energy consumption can be reduced on a voluntary basis. The provision free-of-charge of heat recovered from the drying ovens of the printing presses to a nearby sports facility is discussed. The realisation of an energy consumption analysis and the resulting increases in the efficiency of energy usage in the printing facility are discussed. Further improvements such as the use of variable-frequency compressor drives and heating with natural gas that helped in making energy savings of well over 15% are discussed.

  5. Voluntary Agreements for Energy Efficiency or GHG EmissionsReduction in Industry: An Assessment of Programs Around the World

    Energy Technology Data Exchange (ETDEWEB)

    Price, Lynn

    2005-06-01

    Voluntary agreements for energy efficiency improvement and reduction of energy-related greenhouse gas (GHG) emissions have been a popular policy instrument for the industrial sector in industrialized countries since the 1990s. A number of these national-level voluntary agreement programs are now being modified and strengthened, while additional countries--including some recently industrialized and developing countries--are adopting these type of agreements in an effort to increase the energy efficiency of their industrial sectors.Voluntary agreement programs can be roughly divided into three broad categories: (1) programs that are completely voluntary, (2) programs that use the threat of future regulations or energy/GHG emissions taxes as a motivation for participation, and (3) programs that are implemented in conjunction with an existing energy/GHG emissions tax policy or with strict regulations. A variety of government-provided incentives as well as penalties are associated with these programs. This paper reviews 23 energy efficiency or GHG emissions reduction voluntary agreement programs in 18 countries, including countries in Europe, the U.S., Canada, Australia, New Zealand, Japan, South Korea, and Chinese Taipei (Taiwan) and discusses preliminary lessons learned regarding program design and effectiveness. The paper notes that such agreement programs, in which companies inventory and manage their energy use and GHG emissions to meet specific reduction targets, are an essential first step towards GHG emissions trading programs.

  6. Voluntary participation and cooperation in a collective-good game.

    OpenAIRE

    Kene Boun My; Benoît Chalvignac

    2009-01-01

    We study the effect of voluntary participation in the context of a collective-good experiment. We investigate whether the freedom to participate in the game or not increases contribution levels and enhances their evolution. The analysis of two voluntary participation treatments supports a positive effect of an attractive exit option on both contribution levels and their sustainability. We conclude that the voluntary contribution mechanism can provide sustainable cooperation levels and that th...

  7. Reversal of optic neuropathy secondary to voluntary globe luxation.

    Science.gov (United States)

    Yaman, Aylin; Ozturk, Taylan; Soylev, Meltem F

    2009-04-01

    Luxation of the globe is rare in the general population and may be spontaneous, voluntary, or traumatic. Spontaneous or voluntary globe luxation results from shallow orbit, floppy eyelids, lax orbital ligaments, backward displacement of orbital septum, or proptotic eyes due to orbital tumors or infiltrative processes, as in Grave's ophthalmopathy. The authors report a case with unilateral voluntary globe luxation presented with unilateral progressive visual loss.

  8. Current State of the Voluntary Renewable Energy Market (Presentation)

    Energy Technology Data Exchange (ETDEWEB)

    Heeter, J.

    2013-09-01

    This presentation highlights the status of the voluntary green power market in 2012. The voluntary green power market totaled more than 48 million MWh in 2012, with about 1.9 million customers participating. The supply continues to be dominated by wind, though solar is increasing its share of utility green pricing programs. Prices for voluntary renewable energy certificates (RECs) increased to above $1/MWh.

  9. Voluntary self-touch increases body ownership

    Directory of Open Access Journals (Sweden)

    Masayuki eHara

    2015-10-01

    Full Text Available Experimental manipulations of body ownership have indicated that multisensory integration is central to forming bodily self-representation. Voluntary self-touch is a unique multisensory situation involving corresponding motor, tactile and proprioceptive signals. Yet, even though self-touch is frequent in everyday life, its contribution to the formation of body ownership is not well understood. Here we investigated the role of voluntary self-touch in body ownership using a novel adaptation of the rubber hand illusion (RHI, in which a robotic system and virtual reality allowed participants self-touch of real and virtual hands. In the first experiment, active and passive self-touch were applied in the absence of visual feedback. In the second experiment, we tested the role of visual feedback in this bodily illusion. Finally, in the third experiment, we compared active and passive self-touch to the classical RHI in which the touch is administered by the experimenter. We hypothesized that active self-touch would increase ownership over the virtual hand through the addition of motor signals strengthening the bodily illusion. The results indicated that active self-touch elicited stronger illusory ownership compared to passive self-touch and sensory only stimulation, and indicate an important role of active self-touch in the formation of bodily self.

  10. Preservation of fertility in children treated for cancer.

    Science.gov (United States)

    Wallace, W H B; Thomson, A B

    2003-06-01

    As treatment for childhood cancer has become increasingly successful, adverse effects on reproductive function are assuming greater importance. Preservation of fertility before treatment must be considered in all young patients at high risk of infertility, and provision of such services requires collaboration between oncology centres and assisted conception units. The UK Children's Cancer Study Group is planning to audit current management of preservation of reproductive function in young patients with cancer, and the British Fertility Society is preparing a voluntary code of best practice to guide and inform clinicians and scientists. Limitation of radiation exposure by shielding of the testes and ovaries should be practiced where possible and sperm banking should be offered to all sexually mature boys at risk of infertility. The rapidly advancing experimental techniques for harvesting of gonadal tissue must be considered and embarked on without unrealistic expectations, although future utilisation of the tissue is unlikely to be realised until the next decade.

  11. 16 CFR 1115.5 - Reporting of failures to comply with a voluntary consumer product safety standard relied upon by...

    Science.gov (United States)

    2010-01-01

    ... voluntary consumer product safety standard relied upon by the Commission under section 9 of the CPSA. 1115.5 Section 1115.5 Commercial Practices CONSUMER PRODUCT SAFETY COMMISSION CONSUMER PRODUCT SAFETY ACT REGULATIONS SUBSTANTIAL PRODUCT HAZARD REPORTS General Interpretation § 1115.5 Reporting of failures to...

  12. Comparison of digestion methods to determine heavy metals in fertilizers

    Directory of Open Access Journals (Sweden)

    Ygor Jacques Agra Bezerra da Silva

    2014-04-01

    Full Text Available The lack of a standard method to regulate heavy metal determination in Brazilian fertilizers and the subsequent use of several digestion methods have produced variations in the results, hampering interpretation. Thus, the aim of this study was to compare the effectiveness of three digestion methods for determination of metals such as Cd, Ni, Pb, and Cr in fertilizers. Samples of 45 fertilizers marketed in northeastern Brazil were used. A fertilizer sample with heavy metal contents certified by the US National Institute of Standards and Technology (NIST was used as control. The following fertilizers were tested: rock phosphate; organo-mineral fertilizer with rock phosphate; single superphosphate; triple superphosphate; mixed N-P-K fertilizer; and fertilizer with micronutrients. The substances were digested according to the method recommended by the Ministry for Agriculture, Livestock and Supply of Brazil (MAPA and by the two methods 3051A and 3052 of the United States Environmental Protection Agency (USEPA. By the USEPA method 3052, higher portions of the less soluble metals such as Ni and Pb were recovered, indicating that the conventional digestion methods for fertilizers underestimate the total amount of these elements. The results of the USEPA method 3051A were very similar to those of the method currently used in Brazil (Brasil, 2006. The latter is preferable, in view of the lower cost requirement for acids, a shorter digestion period and greater reproducibility.

  13. [Voluntary wheel running enhances cell proliferation and expression levels of BDNF, IGF1 and WNT4 in dentate gyrus of adult mice].

    Science.gov (United States)

    Yu, Jia-Ling; Ma, Li; Ma, Lan; Tao, Ye-Zheng

    2014-10-25

    Adult hippocampal neurogenesis plays important roles in learning, memory and mood regulation. External factors, such as physical exercise, have been found to modulate adult hippocampal neurogenesis. Voluntary running enhances cell proliferation in subgranular zone (SGZ) and increases the number of new born neurons in rodents, but underlying mechanisms are not fully understood. In this study, we used BrdU assay to identify proliferating cells in 2-month-old C57BL/6 mice after 15 days of voluntary wheel running test. mRNA and protein levels for several neural factors in dentate gyrus, Ammon's horn, and cortex were also analyzed by RT-qPCR and Western blot assay after 15 days of voluntary wheel running. Our data show that voluntary wheel running for 15 days elevated the number of proliferation cells in dentate gyrus and significantly up-regulated the mRNA levels of Bdnf, Igf1 and Wnt4. The protein levels of BDNF and IGF1 in dentate gyrus were also increased after voluntary wheel running. These results indicate that the increase of adult hippocampal neurogenesis caused by voluntary wheel running for 15 days might be through up-regulating BDNF, IGF1 and WNT4 in dentate gyrus.

  14. Fertility outcomes in asthma

    DEFF Research Database (Denmark)

    Gade, Elisabeth Juul; Thomsen, Simon Francis; Lindenberg, Svend

    2016-01-01

    Evidence is increasing of an association between asthma and aspects of female reproduction. However, current knowledge is limited and furthermore relies on questionnaire studies or small populations. In a prospective observational cohort study to investigate whether time to pregnancy, the number...... of fertility treatments, and the number of successful pregnancies differ significantly between women with unexplained infertility with and without asthma.245 women with unexplained infertility (aged 23-45 years) underwent questionnaires and asthma and allergy testing while undergoing fertility treatment. 96...... women entering the study had either a former doctor's diagnosis of asthma or were diagnosed with asthma when included. After inclusion they were followed for a minimum of 12 months in fertility treatment, until they had a successful pregnancy, stopped treatment, or the observation ended.The likelihood...

  15. Sotho fertility symbolism.

    Science.gov (United States)

    Murray, C

    1980-01-01

    This paper deals with the traditional beliefs and mythical folklore of the Sotho-Tswana ethnic tribes of South Africa. Their ritual practices are predominantly concerned with the weather, the vicissitudes of the seasonal cycle, and, especially the rain-making powers of certain individuals. It is well known that rain, in all civilizations, is a symbol of fertility. Thus, adolescent girls and young women, as mediators of the association between water and fertility, can be relied upon to bring the clouds and torrential downpours. The characteristic Sesotho explanation that babies come from the river is clearly an allusion to the water of the womb, and the river is generally recognized as a methaphor of the womb. Also, the onset of menarche involves rituals having to do with the drawing and pouring of water, another clear allusion to the beginning of fertility.

  16. 5 CFR 831.405 - Interest on voluntary contributions.

    Science.gov (United States)

    2010-01-01

    ....405 Section 831.405 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT (CONTINUED) CIVIL SERVICE... contributions stop earning interest on the earliest of— (1) The date when OPM authorizes payment to the... voluntary contributions to purchase additional annuity, voluntary contributions stop earning interest on...

  17. Efficiency of voluntary closing hand and hook prostheses

    NARCIS (Netherlands)

    Smit, G.; Plettenburg, D.H.

    2010-01-01

    The Delft Institute of Prosthetics and Orthotics has started a research program to develop an improved voluntary closing, body-powered hand prosthesis. Five commercially available voluntary closing terminal devices were mechanically tested: three hands [Hosmer APRL VC hand, Hosmer Soft VC Male hand,

  18. Voluntary and involuntary adaptation of gait in Parkinson's disease

    NARCIS (Netherlands)

    Zijlstra, W; Rutgers, AWF; Van Weerden, TW

    1998-01-01

    Voluntary and involuntary adaptation of gait in Parkinson's disease (PD) were studied in two separate experiments. In the first experiment, effects of changes in voluntary control were studied by asking PD patients and age-matched healthy subjects to adapt their walking pattern to visual cues result

  19. Re-Examining the Relationship between Age and Voluntary Turnover

    Science.gov (United States)

    Ng, Thomas W. H.; Feldman, Daniel C.

    2009-01-01

    In their quantitative review of the literature, Healy, Lehman, and McDaniel [Healy, M. C., Lehman, M., & McDaniel, M. A. (1995). Age and voluntary turnover: A quantitative review. "Personnel Psychology, 48", 335-345] concluded that age is only weakly related to voluntary turnover (average r = -0.08). However, with the significant changes in…

  20. Conditioning Bottlenose Dolphins (Tursiops Truncatus Gilli) for Voluntary Diving Studies

    Science.gov (United States)

    1992-12-31

    heartrate (EKG) to validate "voluntary" nature of dive EXAMINE ACTIVE DIVING CONDITIONS (open Ocean Mewwmenr) dive profiles using TDR respiration... heartrate electrodes Open Ocean Experiments ’wear instrument package (TDR) perform voluntary dive up to 200 meters readily present tail flukes for

  1. Students' vocational choices and voluntary action: A 12-nation study

    NARCIS (Netherlands)

    D. Haski-Leventhal (Debbie); R.A. Cnaan (Ram); F. Handy (Femida); J.L. Brudney (Jeffrey); K. Holmes (Kirsten); L. Hustinx (Lesley); C. Kang (Chulhee); M. Kassam (Meenaz); L.C.P.M. Meijs (Lucas); B. Ranade (Bhagyashree); N. Yamauchi (Naoto); A.B. Yeung (Anne Birgitta); S. Zrinscak (Sinisa)

    2008-01-01

    textabstractPrevious research on student involvement suggested that business and engineering students manifest lowest rates of voluntary action. Similarly, it was thought that social science students are the most involved in voluntary action, with students of natural sciences and humanities in the m

  2. Integrating Voluntary Simplicity of Lifestyle into Home Economics.

    Science.gov (United States)

    Pestle, Ruth E.

    This curriculum guide presents guidelines for teaching concepts of Voluntary Simplicity in home economics in Florida. (Voluntary Simplicity is a lifestyle in which individuals choose to live more simply, considering the limited nature of the world's resources.) It is designed for use as a separate unit within different subject matter areas or as…

  3. 5 CFR 831.406 - Withdrawal of voluntary contributions.

    Science.gov (United States)

    2010-01-01

    ... precedence set forth in section 8342(c) of title 5, United States Code, is entitled to payment of the balance... contributions. (a) Before receiving additional annuity payments based on the voluntary contributions, a person who has made voluntary contributions may withdraw the balance while still an employee or Member,...

  4. 78 FR 54444 - Advisory Committee on Voluntary Foreign Aid Meeting

    Science.gov (United States)

    2013-09-04

    ...; ] AGENCY FOR INTERNATIONAL DEVELOPMENT Advisory Committee on Voluntary Foreign Aid Meeting AGENCY: United... Aid (ACVFA). Date: Wednesday, September 18, 2013. Time: 2:30 p.m. to 4:00 p.m. Location: Horizon Room..., Executive Director, Advisory Committee on Voluntary Foreign Aid (ACVFA), U.S. Agency for...

  5. 27 CFR 25.221 - Voluntary destruction of beer.

    Science.gov (United States)

    2010-04-01

    ... beer. 25.221 Section 25.221 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT OF THE TREASURY LIQUORS BEER Voluntary Destruction § 25.221 Voluntary destruction of beer. (a) On brewery premises. (1) A brewer may destroy, at the brewery, beer on which the tax has...

  6. Mouse models in male fertility research

    Institute of Scientific and Technical Information of China (English)

    Duangporn Jamsai; Moira K O'Bryan

    2011-01-01

    Limited knowledge of the genetic causes of male infertility has resulted in few treatment and targeted therapeutic options.Although the ideal approach to identify infertility causing mutations is to conduct studies in the human population,this approach has progressed slowly due to the limitations described herein.Given the complexity of male fertility,the entire process cannot be modeled in vitro.As such,animal models,in particular mouse models,provide a valuable alternative for gene identification and experimentation.Since the introduction of molecular biology and recent advances in animal model production,there has been a substantial acceleration in the identification and characterization of genes associated with many diseases,including infertility.Three major types of mouse models are commonly used in biomedical research,including knockout/knockin/gene-trapped,transgenic and chemical-induced point mutant mice.Using these mouse models,over 400 genes essential for male fertility have been revealed.It has,however,been estimated that thousands of genes are involved in the regulation of the complex process of male fertility,as many such genes remain to be characterized.The current review is by no means a comprehensive list of these mouse models,rather it contains examples of how mouse models have advanced our knowledge of post-natal germ cell development and male fertility regulation.

  7. Adolescent fertility: worldwide concerns.

    Science.gov (United States)

    Senderowitz, J; Paxman, J M

    1985-04-01

    There is growing concern over the adverse health, social, economic, and demographic effects of adolescent fertility. Morbidity and mortality rates ar significantly higher for teenage mothers and their infants, and early initiation of childbearing generally means truncated education, lower future family income, and larger completed family size. Adolescent fertility rates, which largely reflect marriage patterns, range from 4/1000 in Mauritania; in sub-Saharan Africa, virtually all rates are over 100. In most countries, adolescent fertility rates are declining due to rising age at marriage, increased educational and economic opportunities for young women, changes in social customs, increased use of contraception, and access to abortion. However, even if fertility rates were to decline dramatically among adolescent women in developing countries, their sheer numbers imply that their fertility will have a major impact on world population growth in the years ahead. The number of women in the world ages 15-19 years is expected to increase from 245 million in 1985 to over 320 million in the years 2020; 82% of these women live in developing countries. As a result of more and earlier premarital sexual activity, fostered by the lengthening gap between puberty and marriage, diminished parental and social controls, and increasing peer and media pressure to be sexually active, abortion and out-of-wedlock childbearing are increasing among teenagers in many developed and rapidly urbanizing developing countries. Laws and policies regarding sex education in the schools and access to family planning services by adolescents can either inhibit or support efforts to reduce adolescent fertility. Since contraceptive use is often sporadic and ineffective among adolescents, family planning services are crucial. Such programs should aim to reduce adolescents' dependence on abortion through preventive measures and increase awareness of the benefits of delayed sexual activity. Similarly, sex

  8. MUCOSAL IMMUNE SYSTEM AND FERTILITY REGULATION

    Institute of Scientific and Technical Information of China (English)

    BENKun-long

    1989-01-01

    The antisperm antibody classes in serum, peritoneal fluid (PF), uterotubal lavage (UL) and vaginal fluid (VF) from 10 women were compared by indirect immunobead assay, The posiuvc rate of IgA in PF (3 / 10) was similar to that in serum (2/6), whereas

  9. The Trend of Voluntary Warnings in Electronic Nicotine Delivery System Magazine Advertisements

    Science.gov (United States)

    Shang, Ce; Chaloupka, Frank J.

    2017-01-01

    Some manufacturers of electronic nicotine delivery systems (ENDS) voluntarily carried health warnings in their advertisements. This study examined these voluntary warnings in magazine ads and plotted their trends between 2012 and early 2015. ENDS magazine ads were obtained through Kantar media and warnings were collected from the Chicago Public Library or the Trinkets and Trash surveillance system. The prevalence of voluntary warnings, warnings with the specific capitalized word “WARNING”, and MarkTen warnings were examined after being weighted using factors related to exposure between January 2012 and March 2015. Five brands (MarkTen, NJOY, MISTIC, and some Blu) carried warnings during the study period. The prevalence of warnings post 2012 that contained a description of nicotine did not significantly increase until the launch of MarkTen, which also happened several months before April 2014 when the U.S. food and drug administration (FDA) published its proposed deeming rule. In addition, none of these warnings met the criteria required by the FDA in the final rules. Voluntary warnings, particularly MarkTen warnings, significantly increased in ENDS magazine ads between 2014 and 2015. It is important to monitor how ENDS manufacturers will comply with the FDA regulation related to warnings and how this regulation will ultimately impact ENDS risk perceptions and use. PMID:28075420

  10. The Trend of Voluntary Warnings in Electronic Nicotine Delivery System Magazine Advertisements

    Directory of Open Access Journals (Sweden)

    Ce Shang

    2017-01-01

    Full Text Available Some manufacturers of electronic nicotine delivery systems (ENDS voluntarily carried health warnings in their advertisements. This study examined these voluntary warnings in magazine ads and plotted their trends between 2012 and early 2015. ENDS magazine ads were obtained through Kantar media and warnings were collected from the Chicago Public Library or the Trinkets and Trash surveillance system. The prevalence of voluntary warnings, warnings with the specific capitalized word “WARNING”, and MarkTen warnings were examined after being weighted using factors related to exposure between January 2012 and March 2015. Five brands (MarkTen, NJOY, MISTIC, and some Blu carried warnings during the study period. The prevalence of warnings post 2012 that contained a description of nicotine did not significantly increase until the launch of MarkTen, which also happened several months before April 2014 when the U.S. food and drug administration (FDA published its proposed deeming rule. In addition, none of these warnings met the criteria required by the FDA in the final rules. Voluntary warnings, particularly MarkTen warnings, significantly increased in ENDS magazine ads between 2014 and 2015. It is important to monitor how ENDS manufacturers will comply with the FDA regulation related to warnings and how this regulation will ultimately impact ENDS risk perceptions and use.

  11. Voluntary chemical castration of a mental patient.

    Science.gov (United States)

    Brahams, D

    1988-06-01

    Britain's High Court recently overruled two decisions of the Mental Health Act Commission that denied certification of a voluntary experimental drug treatment to a mental patient, holding that the standard for informed consent is determined not by the subjective judgment of the commissioners but by whether the patient knows the nature and likely effects of treatment and that its use in his case is a novel one. The background facts of the case involving a 27-year-old pedophile receiving goserelin implantations to reduce testosterone levels are presented and the issues of jurisdiction under the Mental Health Act 1983 and the commissioners' duty to act fairly and to consider the likely benefits of treatment are discussed.

  12. Fertility and the economy.

    Science.gov (United States)

    Becker, G S

    1992-08-01

    Fertility and the economy is examined in the context of the Malthusian question about the links between family choices and longterm economic growth. Micro level differences are not included not are a comprehensive range of economic or determinant variables. Specific attention is paid to income and price effects, the quality of children, overlapping generations, mortality effects, uncertainty, and economic growth. Fertility and the demand for children in linked to parental incomes and the cost of rearing children, which is affected by public policies that change the costs. Demand is also related to child and adult mortality, and uncertainty about sex of the child. Fertility in one generation affects fertility in the next. Malthusian and neoclassical models do not capture the current model of modern economies with rising income/capita and human and physical capital, extensive involvement of married women in the labor force, and declining fertility to very low levels. In spite of the present advances in firm knowledge about the relationships between fertility and economic and social variables, there is still much greater ignorance of the interactions. The Malthusian utility function that says fertility rises and falls with income did hold up to 2 centuries of scrutiny, and the Malthusian inclusion of the shifting tastes in his analysis could be translated in the modern context to include price of children. The inclusion of net cost has significant consequences, i.e., rural fertility can be higher because the cost of rearing when children contribute work to maintaining the farm is lower than in the city. An income tax deduction for children in the US reduces cost. Economic growth raises the cost of children due the time spent on child care becoming more valuable. The modern context has changed from Malthusian time, and the cost of education, training, and medical care is relevant. The implication is that a rise in income could reduce the demand for children when

  13. Lateral asymmetry of voluntary attention orienting

    Directory of Open Access Journals (Sweden)

    B.A. Castro-Barros

    2010-08-01

    Full Text Available We recently demonstrated that automatic attention favors the right side of space and, in the present study, we investigated whether voluntary attention also favors this side. Six reaction time experiments were conducted. In each experiment, 12 new 18-25-year-old male right-handed individuals were tested. In Experiments 1, 2, 3 (a, b and 4 (a, b, tasks with increasing attentional demands were used. In Experiments 1, 2, 3a, and 4a, attention was oriented to one or both sides by means of a central spatially informative visual cue. A left or right side visual target appeared 100, 300, or 500 ms later. Attentional effects were observed in the four experiments. In Experiments 2, 3a and 4a, these effects were greater when the cue indicated the right side than when it indicated the left side (respectively: 16 ± 10 and 44 ± 6 ms, P = 0.015, for stimulus onset asynchrony of 500 ms in Experiment 2; 38 ± 10 and 70 ± 7 ms, P = 0.011, for Experiment 3a, and 23 ± 11 and 61 ± 10 ms, P = 0.009, for Experiment 4a. In Experiments 3b and 4b, the central cue pointed to both sides and was said to be non-relevant for task performance. In these experiments right and left reaction times did not differ. The most conservative interpretation of the present findings is that voluntary attention orienting favors the right side of space, particularly when a difficult task has to be performed.

  14. Nonpoint source water pollution abatement and the feasibility of voluntary programs

    Science.gov (United States)

    Sawicki, David S.; Judd, Lynne B.

    1983-09-01

    This article details a case study of a voluntary, decentralized institutional arrangement for nonpint source water pollution control used in the Root River watershed in southeastern Wisconsin. This watershed was chosen because of its mix of urban, agricultural, and urbanizing land uses. The project objectives were to monitor and draw conclusions about the effectiveness of a voluntary, decentralized institutional system, to specify deficiencies of the approach and suggest means to correct them, and to use the conclusions to speculate about the need for regulations regarding nonpoint source pollution control or the appropriateness of financial incentives for nonpoint source control. Institutional factors considered include diversity of land uses in the watershed, educational needs, economic conditions, personality, water quality, number of agencies involved, definition of authority, and bureaucratic requirements

  15. Soil microbes and plant fertilization.

    Science.gov (United States)

    Miransari, Mohammad

    2011-12-01

    With respect to the adverse effects of chemical fertilization on the environment and their related expenses, especially when overused, alternative methods of fertilization have been suggested and tested. For example, the combined use of chemical fertilization with organic fertilization and/or biological fertilization is among such methods. It has been indicated that the use of organic fertilization with chemical fertilization is a suitable method of providing crop plants with adequate amount of nutrients, while environmentally and economically appropriate. In this article, the importance of soil microbes to the ecosystem is reviewed, with particular emphasis on the role of plant growth-promoting rhizobacteria, arbuscular mycorrhizal fungi, and endophytic bacteria in providing necessary nutrients for plant growth and yield production. Such microbes are beneficial to plant growth through colonizing plant roots and inducing mechanisms by which plant growth increases. Although there has been extensive research work regarding the use of microbes as a method of fertilizing plants, it is yet a question how the efficiency of such microbial fertilization to the plant can be determined and increased. In other words, how the right combination of chemical and biological fertilization can be determined. In this article, the most recent advances regarding the effects of microbial fertilization on plant growth and yield production in their combined use with chemical fertilization are reviewed. There are also some details related to the molecular mechanisms affecting the microbial performance and how the use of biological techniques may affect the efficiency of biological fertilization.

  16. Oviduct: roles in fertilization and early embryo development.

    Science.gov (United States)

    Li, Shuai; Winuthayanon, Wipawee

    2017-01-01

    Animal oviducts and human Fallopian tubes are a part of the female reproductive tract that hosts fertilization and pre-implantation development of the embryo. With an increasing understanding of roles of the oviduct at the cellular and molecular levels, current research signifies the importance of the oviduct on naturally conceived fertilization and pre-implantation embryo development. This review highlights the physiological conditions within the oviduct during fertilization, environmental regulation, oviductal fluid composition and its role in protecting embryos and supplying nutrients. Finally, the review compares different aspects of naturally occurring fertilization and assisted reproductive technology (ART)-achieved fertilization and embryo development, giving insight into potential areas for improvement in this technology. © 2017 Society for Endocrinology.

  17. Priming voluntary autobiographical memories: Implications for the organisation of autobiographical memory and voluntary recall processes.

    Science.gov (United States)

    Mace, John H; Clevinger, Amanda M

    2013-01-01

    The goal of this study was to show that voluntary autobiographical memories could be primed by the prior activation of autobiographical memories. Three experiments demonstrated voluntary memory priming with three different approaches. In Experiment 1 primed participants were asked to recall memories from their elementary school years. In a subsequent memory task primed participants were asked to recall memories from any time period, and they produced significantly more memories from their elementary school years than unprimed participants. In Experiment 2 primed participants were asked to recall what they were doing when they had heard various news events occurring between 1998 and 2005. Subsequently these participants produced significantly more memories from this time period than unprimed participants. In Experiment 3 primed participants were asked to recall memories from their teenage years. Subsequently these participants were able to recall more memories from ages 13-15 than unprimed participants, where both had only 1 second to produce a memory. We argue that the results support the notion that episodic memories can activate one another and that some of them are organised according to lifetime periods. We further argue that the results have implications for the reminiscence bump and voluntary recall of the past.

  18. Intenções reprodutivas e práticas de regulação da fecundidade entre universitários Reproductive intentions and fertility regulation practices among university students

    Directory of Open Access Journals (Sweden)

    Kátia Cibelle Machado Pirotta

    2004-08-01

    Full Text Available OBJETIVO: Identificar as intenções reprodutivas e caracterizar as práticas de regulação da fecundidade, abarcando a contracepção e o aborto, entre um grupo de adolescentes e jovens de alta escolaridade. MÉTODOS: Os dados foram levantados a partir de um estudo amplo quali-quantitativo com estudantes de graduação com idade de até 24 anos, de uma universidade pública estadual localizada na cidade de São Paulo. A população estudada foi constituída de 952 estudantes que freqüentavam disciplinas sorteadas pelo método de sorteio aleatório; e numa segunda etapa foram realizadas 33 entrevistas em profundidade com alunos voluntários. Na primeira etapa, os alunos foram entrevistados em sala de aula, através de um questionário auto-aplicável e, na segunda etapa, foram gravadas entrevistas em profundidade, realizadas em um local previamente combinado. RESULTADOS: O padrão de família idealizado pelo grupo era pequeno, com até dois filhos. A idade considerada ideal no nascimento do primeiro filho seria próxima aos 30 anos. Os estudantes referiram uma alta proporção de uso de contraceptivos - sobretudo do condom e da pílula. Ao lado disso, observa-se uma alta proporção de gestações finalizadas pelo aborto. Como resultante desse quadro, a fecundidade é bastante baixa no grupo, ou seja, 27 estudantes referiram uma ou mais gestações. Os dados qualitativos não foram objeto de análise. CONCLUSÕES: Embora o tamanho idealizado para a família reflita uma tendência geral presente na sociedade brasileira, constata-se que o grupo adia a maternidade/paternidade em função de um projeto de vida orientado para a conclusão de um curso superior e a inserção no mercado de trabalho. Ainda assim, a contracepção e a prevenção das doenças sexualmente transmissíveis são vivenciadas precariamente.OBJECTIVE: To identify reproductive intentions and fertility regulation practices, including contraception and abortion, in a group of

  19. Genetics, genomics and fertility

    Science.gov (United States)

    In order to enhance the sustainability of dairy businesses, new management tools are needed to increase the fertility of dairy cattle. Genomic selection has been successfully used by AI studs to screen potential sires and significantly decrease the generation interval of bulls. Buoyed by the success...

  20. Fertility and Infertility.

    Science.gov (United States)

    Orgebin-Crist, Marie-Claire; And Others

    In this report, emphasis is placed on major research developments in the reproductive sciences, their impact on the health of individuals as well as on that of society, and on current trends that may provide new opportunities for future research in fertility and infertility. In the first section, major developments in the reproductive sciences are…

  1. Fertility and Infertility.

    Science.gov (United States)

    Orgebin-Crist, Marie-Claire; And Others

    In this report, emphasis is placed on major research developments in the reproductive sciences, their impact on the health of individuals as well as on that of society, and on current trends that may provide new opportunities for future research in fertility and infertility. In the first section, major developments in the reproductive sciences are…

  2. Sperm preparation for fertilization

    NARCIS (Netherlands)

    Gadella, B.M.

    2014-01-01

    Description This book contains 19 chapters that discuss theoretical and applied andrology for domestic, zoo and wild animals. Topics include semen and its constituents; sperm production and harvest; determinants of sperm morphology; sperm preparation for fertilization; practical aspects of semen cry

  3. Mobility, Fertility, and Residential Crowding

    Science.gov (United States)

    Morris, Earl W.

    1977-01-01

    Regression analyses predicting fertility and mobility in a sample of a metropolitan county in New York State indicate that residential mobility serves to release the negative pressure that residential crowding might exert on fertility behavior. (Author)

  4. Agriculture: Nutrient Management and Fertilizer

    Science.gov (United States)

    Fertilizers and soil amendments can be derived from raw materials, composts and other organic matter, and wastes, such as sewage sludge and certain industrial wastes. Overuse of fertilizers can result in contamination of surface water and groundwater.

  5. Sex and Fertility After SCI

    Science.gov (United States)

    ... About Blog Facing Disability Jeff Shannon Donate Experts \\ Sex and Fertility After Spinal Cord Injury Topics Adult ... Spasticity, Physical Therapy-Lokomat Spasticity, Physical Therapy-Lokomat Sex and Fertility After Spinal Cord Injury Sex and ...

  6. Land Use and Land Cover - MO 2008 Brownfields Voluntary Cleanup Program Sites (SHP)

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — The Brownfields/Voluntary Cleanup Program (BVCP) provides property buyers, sellers, developers, bankers, development agencies, local government and other voluntary...

  7. Cardiovascular responses to voluntary and nonvoluntary static exercise in humans.

    Science.gov (United States)

    Friedman, D B; Peel, C; Mitchell, J H

    1992-11-01

    We have measured the cardiovascular responses during voluntary and nonvoluntary (electrically induced) one-leg static exercise in humans. Eight normal subjects were studied at rest and during 5 min of static leg extension at 20% of maximal voluntary contraction performed voluntarily and nonvoluntarily in random order. Heart rate (HR), mean arterial pressure (MAP), and cardiac output (CO) were determined, and peripheral vascular resistance (PVR) and stroke volume (SV) were calculated. HR increased from approximately 65 +/- 3 beats/min at rest to 80 +/- 4 and 78 +/- 6 beats/min (P voluntary and nonvoluntary contractions, respectively. CO increased from 5.1 +/- 0.7 to 6.0 +/- 0.8 and 6.2 +/- 0.8 l/min (P voluntary and nonvoluntary contractions, respectively. PVR and SV did not change significantly during voluntary or nonvoluntary contractions. Thus the cardiovascular responses were not different between voluntary and electrically induced contractions. These results suggest that the increases in CO, HR, SV, MAP, and PVR during 5 min of static contractions can be elicited without any contribution from a central neural mechanism (central command). However, central command could still have an important role during voluntary static exercise.

  8. Voluntary Noise Mapping for Smart City

    Science.gov (United States)

    Poslončec-Petrić, V.; Vuković, V.; Frangeš, S.; Bačić, Ž.

    2016-09-01

    One of the main concept objectives of smart cities is to create a quality living environment that is long-term sustainable and economically justified. In that context, modern cities are aware of the exposure to various forms of physical and non-physical pollution that needs to be remediated, eliminated or reduced. To achieve that it is necessary to quality determine the sources and reasons of each pollution. The most prominent examples of physical pollution that affects the quality of life of citizens in cities are light and noise pollution. Noise pollution or noise, is mostly the consequence of road and rail traffic in cities and it directly affects the health of citizens. Traffic control, reduction of peak congestion, dispersion and traffic redirection or building protective barriers, are ways that cities use to reduce the amount of noise or its effects. To make these measures efficient it is necessary to obtain the information related to the level of noise in certain areas, streets, cities. To achieve this, smart cities use noise mapping. The city of Zagreb since 2012, participates in the i-SCOPE project (interoperable Smart City services trough Open Platform for urban Ecosystems). i-SCOPE delivers an open platform on top of which it develops, three "smart city" services: optimization of energy consumption through a service for accurate assessment of solar energy potential and energy loss at building level, environmental monitoring through a real-time environmental noise mapping service leveraging citizen's involvement will who act as distributed sensors city-wide measuring noise levels through an application on their mobile phones and improved inclusion and personal mobility of aging and diversely able citizens through an accurate personal routing service. The students of Faculty of Geodesy University of Zagreb, who enrolled in the course Thematic Cartography, were actively involved in the voluntary data acquisition in order to monitor the noise in real time

  9. VOLUNTARY NOISE MAPPING FOR SMART CITY

    Directory of Open Access Journals (Sweden)

    V. Poslončec-Petrić

    2016-09-01

    Full Text Available One of the main concept objectives of smart cities is to create a quality living environment that is long-term sustainable and economically justified. In that context, modern cities are aware of the exposure to various forms of physical and non-physical pollution that needs to be remediated, eliminated or reduced. To achieve that it is necessary to quality determine the sources and reasons of each pollution. The most prominent examples of physical pollution that affects the quality of life of citizens in cities are light and noise pollution. Noise pollution or noise, is mostly the consequence of road and rail traffic in cities and it directly affects the health of citizens. Traffic control, reduction of peak congestion, dispersion and traffic redirection or building protective barriers, are ways that cities use to reduce the amount of noise or its effects. To make these measures efficient it is necessary to obtain the information related to the level of noise in certain areas, streets, cities. To achieve this, smart cities use noise mapping. The city of Zagreb since 2012, participates in the i-SCOPE project (interoperable Smart City services trough Open Platform for urban Ecosystems. i-SCOPE delivers an open platform on top of which it develops, three "smart city" services: optimization of energy consumption through a service for accurate assessment of solar energy potential and energy loss at building level, environmental monitoring through a real-time environmental noise mapping service leveraging citizen's involvement will who act as distributed sensors city-wide measuring noise levels through an application on their mobile phones and improved inclusion and personal mobility of aging and diversely able citizens through an accurate personal routing service. The students of Faculty of Geodesy University of Zagreb, who enrolled in the course Thematic Cartography, were actively involved in the voluntary data acquisition in order to monitor the

  10. The impact of cross-border reproductive care or 'fertility tourism' on NHS maternity services.

    Science.gov (United States)

    McKelvey, A; David, A L; Shenfield, F; Jauniaux, E R

    2009-10-01

    High order multiple pregnancies have substantial morbidity and mortality. Fertility treatment is commonly responsible for their conception and is available globally with variable regulation. We investigated cross-border fertility treatment in these pregnancies in a UK fetal medicine unit, recording mode of conception, country of fertility treatment, reason for non-UK treatment and fetal reduction. Over an 11-year period, 109 women had a high order multiple pregnancy. Ninety-four women (86%) conceived with fertility treatment of whom 24 (26%) had this performed overseas. Cross-border fertility treatment poses an increasing challenge to obstetricians. National data on its occurrence is urgently needed.

  11. Energy metabolism and fertility: a balance preserved for female health.

    OpenAIRE

    Sara Della Torre; Valeria Benedusi; Roberta Fontana; Adriana Maggi

    2013-01-01

    In female animals, energy metabolism and fertility are tightly connected, and reciprocally regulated. However, the relative contributions of metabolic and reproductive pathways have changed over the course of evolution. In oviparous animals, metabolic factors take precedence over fertility, enabling egg production to be inhibited in a nutritionally poor environment. By contrast, in placental mammals, the opposite occurs: the need to feed a developing embryo and neonate forces metabolic pathwa...

  12. The spinal reflex cannot be perceptually separated from voluntary movements.

    Science.gov (United States)

    Ghosh, Arko; Haggard, Patrick

    2014-01-01

    Both voluntary and involuntary movements activate sensors in the muscles, skin, tendon and joints. As limb movement can result from a mixture of spinal reflexes and voluntary motor commands, the cortical centres underlying conscious proprioception might either aggregate or separate the sensory inputs generated by voluntary movements from those generated by involuntary movements such as spinal reflexes. We addressed whether healthy volunteers could perceive the contribution of a spinal reflex during movements that combined both reflexive and voluntary contributions. Volunteers reported the reflexive contribution in leg movements that were partly driven by the knee-jerk reflex induced by a patellar tendon tap and partly by voluntary motor control. In one condition, participants were instructed to kick back in response to a tendon tap. The results were compared to reflexes in a resting baseline condition without voluntary movement. In a further condition, participants were instructed to kick forwards after a tap. Volunteers reported the perceived reflex contribution by repositioning the leg to the perceived maximum displacement to which the reflex moved the leg after each tendon tap. In the resting baseline condition, the reflex was accurately perceived. We found a near-unity slope of linear regressions of perceived on actual reflexive displacement. Both the slope value and the quality of regression fit in individual volunteers were significantly reduced when volunteers were instructed to generate voluntary backward kicks as soon as they detected the tap. In the kick forward condition, kinematic analysis showed continuity of reflex and voluntary movements, but the reflex contribution could be estimated from electromyography (EMG) recording on each trial. Again, participants' judgements of reflexes showed a poor relation to reflex EMG, in contrast to the baseline condition. In sum, we show that reflexes can be accurately perceived from afferent information. However

  13. Interaction of Compliance and Voluntary Renewable Energy Markets

    Energy Technology Data Exchange (ETDEWEB)

    Bird, L.; Lokey, E.

    2007-10-01

    In recent years, both compliance and voluntary markets have emerged to help support the development of renewable energy resources. Both of these markets are growing rapidly and today about half of U.S. states have RPS policies in place, with a number of these policies adopted in the last several years. In addition, many states have recently increased the stringency of their RPS policies. This paper examines key market interaction issues between compliance and voluntary renewable energy markets. It provides an overview of both the compliance and voluntary markets, addressing each market's history, purpose, size, scope, and benefits while addressing issues, including double counting.

  14. Interaction of Compliance and Voluntary Renewable Energy Markets

    Energy Technology Data Exchange (ETDEWEB)

    Bird, Lori [National Renewable Energy Lab. (NREL), Golden, CO (United States); Lokey, Elizabeth [National Renewable Energy Lab. (NREL), Golden, CO (United States)

    2007-10-01

    In recent years, both compliance and voluntary markets have emerged to help support the development of renewable energy resources. Both of these markets are growing rapidly and today about half of U.S. states have RPS policies in place, with a number of these policies adopted in the last several years. In addition, many states have recently increased the stringency of their RPS policies. This paper examines key market interaction issues between compliance and voluntary renewable energy markets. It provides an overview of both the compliance and voluntary markets, addressing each market's history, purpose, size, scope, and benefits while addressing issues, including double counting.

  15. Ecological Research of the Voluntary Disclosure about Listed Companies

    Science.gov (United States)

    Hu, Jing-Jing; Yan, Guang-Le

    In the paper, the research subject is the ecological relationship between the Small and Medium-sized Enterprises(SMEs) and the Large-scale Enterprises(Les). From the perspective of ecology, setting up the competitive model basic on the Logistic model, and carrying out further analysis about the voluntary information disclosure of listed company, then getting the strategic choice about the voluntary information disclosure and the ecological explanation of false information, and the dynamic mechanism and strategy of the voluntary information disclosure of listed company.

  16. Relationships between nutrient-related plant traits and combinations of soil N and P fertility measures.

    Directory of Open Access Journals (Sweden)

    Yuki Fujita

    Full Text Available Soil fertility and nutrient-related plant functional traits are in general only moderately related, hindering the progress in trait-based prediction models of vegetation patterns. Although the relationships may have been obscured by suboptimal choices in how soil fertility is expressed, there has never been a systematic investigation into the suitability of fertility measures. This study, therefore, examined the effect of different soil fertility measures on the strength of fertility-trait relationships in 134 natural plant communities. In particular, for eight plot-mean traits we examined (1 whether different elements (N or P have contrasting or shared influences, (2 which timescale of fertility measures (e.g. mineralization rates for one or five years has better predictive power, and (3 if integrated fertility measures explain trait variation better than individual fertility measures. Soil N and P had large mutual effects on leaf nutrient concentrations, whereas they had element-specific effects on traits related to species composition (e.g. Grime's CSR strategy. The timescale of fertility measures only had a minor impact on fertility-trait relationships. Two integrated fertility measures (one reflecting overall fertility, another relative availability of soil N and P were related significantly to most plant traits, but were not better in explaining trait variation than individual fertility measures. Using all fertility measures together, between-site variations of plant traits were explained only moderately for some traits (e.g. 33% for leaf N concentrations but largely for others (e.g. 66% for whole-canopy P concentration. The moderate relationships were probably due to complex regulation mechanisms of fertility on traits, rather than to a wrong choice of fertility measures. We identified both mutual (i.e. shared and divergent (i.e. element-specific and stoichiometric effects of soil N and P on traits, implying the importance of explicitly

  17. Relationships between nutrient-related plant traits and combinations of soil N and P fertility measures.

    Science.gov (United States)

    Fujita, Yuki; van Bodegom, Peter M; Witte, Jan-Philip M

    2013-01-01

    Soil fertility and nutrient-related plant functional traits are in general only moderately related, hindering the progress in trait-based prediction models of vegetation patterns. Although the relationships may have been obscured by suboptimal choices in how soil fertility is expressed, there has never been a systematic investigation into the suitability of fertility measures. This study, therefore, examined the effect of different soil fertility measures on the strength of fertility-trait relationships in 134 natural plant communities. In particular, for eight plot-mean traits we examined (1) whether different elements (N or P) have contrasting or shared influences, (2) which timescale of fertility measures (e.g. mineralization rates for one or five years) has better predictive power, and (3) if integrated fertility measures explain trait variation better than individual fertility measures. Soil N and P had large mutual effects on leaf nutrient concentrations, whereas they had element-specific effects on traits related to species composition (e.g. Grime's CSR strategy). The timescale of fertility measures only had a minor impact on fertility-trait relationships. Two integrated fertility measures (one reflecting overall fertility, another relative availability of soil N and P) were related significantly to most plant traits, but were not better in explaining trait variation than individual fertility measures. Using all fertility measures together, between-site variations of plant traits were explained only moderately for some traits (e.g. 33% for leaf N concentrations) but largely for others (e.g. 66% for whole-canopy P concentration). The moderate relationships were probably due to complex regulation mechanisms of fertility on traits, rather than to a wrong choice of fertility measures. We identified both mutual (i.e. shared) and divergent (i.e. element-specific and stoichiometric) effects of soil N and P on traits, implying the importance of explicitly

  18. Corporate volunteering - motivation for voluntary work

    Directory of Open Access Journals (Sweden)

    Debora Azevedo

    2008-07-01

    Full Text Available Nowadays, when the welfare state is a responsibility of the entire society, organizations in the private sector assume co-responsibility for social issues. They are also pressured by the challenges presented by technological advances and the globalization , involving new parameters and requirements for quality. In this context, the concept of Corporate Social Responsibility (RSC emerges as an option for solutions to the issues related to the company and the whole community. Among the actions of the RSC is the Corporate Volunteering-program, which aims to promote / encourage employes to do voluntary work. A central issue when talking about volunteering is the withdrawal of these (SILVA and FEITOSA, 2002; TEODÓSIO, 1999 and, in accordance with the Community Solidarity (1997, one of the possible causes for the withdrawal is the lack of clarity as to the motives and expectations that lead the person to volunteer themselves. This study uses qualitative research and triangulation of feedback from volunteers, coordinators of volunteers and social organizations, to present a framework from which it is possible to analyze the various motivations for the volunteer work. Key words: Corporate Volunteering program. Volunteering. Corporate social responsibility.

  19. Expectations and voluntary attrition in nursing students.

    Science.gov (United States)

    O'Donnell, Hugh

    2011-01-01

    This paper presents a series of findings generated during a larger study which aimed to develop a theoretical understanding of the reasons why nursing students voluntarily leave pre-registration nursing programmes. In this study, significant incongruence was found to exist between student expectations of pre-registration nursing programmes and the reality of these programmes following entry. The resulting dissonance was identified as an important factor in student decisions to voluntarily withdraw. A single case study design was selected to explore the causes of voluntary attrition in nursing students within a School of Nursing and Midwifery. The study population was obtained through purposeful sampling and consisted of 15 students who had previously voluntarily withdrawn from pre-registration nursing programmes. A semi-structured interview method was used to collect data from study participants. The interview schedule developed for use in the study reflected the key components of the conceptual model of higher education (HE) student attrition (Tinto, 1975, 1987, 1993). All interviews were tape recorded to facilitate later transcription. The Cyclical or Interactive Model of Qualitative Research (Miles and Huberman, 1994) was used to analyse data collected from study participants. This paper describes the unrealistic range of expectations which nursing students have of nursing, the information sources and experiences which inform student expectations and how ambiguous expectations contributed to voluntarily attrition.

  20. Perceived coercion in voluntary hospital admission.

    LENUS (Irish Health Repository)

    O'Donoghue, Brian

    2014-01-30

    The legal status of service users admitted to psychiatric wards is not synonymous with the level of coercion that they can perceive during the admission. This study aimed to identify and describe the proportion of individuals who were admitted voluntarily but experienced levels of perceived coercion comparable to those admitted involuntarily. Individuals admitted voluntarily and involuntarily to three psychiatric hospitals were interviewed using the MacArthur Admission Experience Interview and the Structured Clinical Interview for DSM-IV diagnoses. One hundered sixty-one individuals were interviewed and 22% of the voluntarily admitted service users had levels of perceived coercion similar to that of the majority of involuntarily admitted service users. Voluntarily admitted service users who experienced high levels of perceived coercion were more likely to have more severe psychotic symptoms, have experienced more negative pressures and less procedural justices on admission. Individuals brought to hospital under mental health legislation but who subsequently agreed to be admitted voluntarily and those treated on a secure ward also reported higher levels of perceived coercion. It needs to be ensured that if any service user, whether voluntary or involuntary, experiences treatment pressures or coercion that there is sufficient oversight of the practice, to ensure that individual\\'s rights are respected.

  1. Helping from the heart: Voluntary upregulation of heart rate variability predicts altruistic behavior.

    Science.gov (United States)

    Bornemann, Boris; Kok, Bethany E; Böckler, Anne; Singer, Tania

    2016-09-01

    Our various daily activities continually require regulation of our internal state. These regulatory processes covary with changes in High Frequency Heart Rate Variability (HF-HRV), a marker of parasympathetic activity. Specifically, incidental increases in HF-HRV accompany positive social engagement behavior and prosocial action. Little is known about deliberate regulation of HF-HRV and the role of voluntary parasympathetic regulation in prosocial behavior. Here, we present a novel biofeedback task that measures the ability to deliberately increase HF-HRV. In two large samples, we find that a) participants are able to voluntarily upregulate HF-HRV, and b) variation in this ability predicts individual differences in altruistic prosocial behavior, but not non-altruistic forms of prosociality, assessed through 14 different measures. Our findings suggest that self-induction of parasympathetic states is involved in altruistic action. The biofeedback task may provide a measure of deliberate parasympathetic regulation, with implications for the study of attention, emotion, and social behavior.

  2. Social mobility and fertility

    Directory of Open Access Journals (Sweden)

    Gianpiero Dalla Zuanna

    2007-12-01

    Full Text Available Intra- and inter-generational social mobility have in the past played an important role in attempts to explain fertility behaviour, and continue to do so today. The opinions expressed by social scientists in the first part of the 20th century are renewed and confirmed. More specifically: (1 intra-generational social mobility has been reinforced by the personal well-being aspirations and job careers of women; (2 status anxiety parents feel for their children pushes fertility down in large areas of the developed world (mainly in southern European and eastern Asian countries. Therefore, the provocative idea of Ariès that in the rich world, the child-king has now been replaced by the couple-queen does not perfectly hold.

  3. Fertility, Migration, and Altruism

    OpenAIRE

    2000-01-01

    Consider migration to a higher income region as a human capital investment in which parents bear migration costs and children share returns. Migrants from a population with heterogeneous intergenerational discount rates will be self-selected on intergenerational altruism. Thus, immigrants may be self-selected on fertility. Soviet Jews who migrate to Israel despite high migration costs have significantly more children than members of the same birth cohort who migrate later when costs are low. ...

  4. Slow-Release Fertilizer

    Science.gov (United States)

    1998-01-01

    Under an SBIR (Small Business Innovative Research), ZeoponiX, Inc., introduced ZeoPro. This product is used as a fertilizer/soil amendment for golf courses, ball fields, greenhouse and horticultural uses. A combination of superior growth medium and soil conditioner allow for nutrient supplementation and high efficiency delivery of nutrients throughout the plant. ZeoPro provides a balanced nutrient system for major, minor, and trace nutrients.

  5. The fertility decline in Kenya.

    Science.gov (United States)

    Robinson, W C; Harbison, S F

    1995-01-01

    In Sub-Saharan Africa Kenya is a prime example of a country experiencing a rapid decline in fertility and greater contraceptive prevalence. These changes have occurred since 1980 when fertility was high at 8.0 children per woman. In 1993 the total fertility rate (TFR) was 5.4, and the growth rate declined to about 2.0%. This transition is swifter than any country in contemporary Asia or historical Europe. The likely projection for Kenya is attainment of replacement level fertility during the 2020s and a leveling of population at about 100 million persons. Fertility has declined the most in urban areas and central and eastern regions. Bongaarts' proximate determinants (TFR, total marital fertility rate, total natural marital fertility rate, and total fecundity) are reduced to the proportion of currently married women using contraception, the proportion in lactational nonfecund status, and the proportion currently married. Actual fertility change is accounted for by total fertility change of 3.0 children. Lactational infecundability accounts for 0.5 potential births, and changes in marital fertility account for 1.0 reduced births per woman. About 70% of fertility reduction is accounted for by contraception and abortion. During 1977-78 80% of fertility control was due to lactational nonfecundity, 10% to nonmarriage, and 10% to contraception. In 1993 lactational nonfecundity accounted for 50% of the reduction, nonmarriage for 20%, and abortion about 30%. Future fertility is expected to be dependent on contraceptive prevalence. Kenya has experienced the Coale paradigm of preconditions necessary for demographic transition (willing, ready, and able). High fertility in Africa is not intractable. Creating the change in attitudes that leads to readiness is linked to education, health, and exposure to modernizing media and urban lifestyles. The public sector family planning program in Kenya has created the opportunity for access and availability of contraception. The key

  6. IN VITRO FERTILIZATION

    Directory of Open Access Journals (Sweden)

    Hadawale N. M

    2011-07-01

    Full Text Available First written document dealing with infertility may be found in the Kahoun papyrus (oldest Egyptian medical text, dated to 2200-1950 BC. The early attribution of infertility to women persisted for centuries and was often considered divine punishment.Infertility means 1 year of well-timed, unprotected intercourse without a pregnancy. The study shows about 10-15% of population is infertile. And 15-20% of couple have unexplained infertility (work-up is negative. Normally women are born with their lifetime egg supply, the Fertility initially declines at age 27.Significant decline at age 37-38. The chances of pregnancies are rare after age 44 besides this defect in female ovary, fallopian tube, uterus, and fibroid tumour causes infertility in female.Abnormality in sperm production and abnormality in sperm function causes infertility in male.To overcome the infertility egg are harvested from womens ovary and fertilized in laboratory with the sperm the embryos are then transfer into uterus known as In Vitro Fertilization.

  7. Environmental friendly nitrogen fertilization

    Institute of Scientific and Technical Information of China (English)

    Avi; Shaviv

    2005-01-01

    With the huge intensification of agriculture and the increasing awareness to human health and natural resources sustainability, there was a shift towards the development of environmental friendly N application approaches that support sustainable use of land and sustain food production.The effectiveness of such approaches depends on their ability to synchronize plant nitrogen demand with its supply and the ability to apply favored compositions and dosages of N-species.They are also influenced by farming scale and its sophistication, and include the following key concepts: (i) Improved application modes such as split or localized ("depot") application; (ii) use of bio-amendments like nitrification and urease inhibitors and combinations of (i) and (ii); (iii) use of controlled and slow release fertilizers; (iv) Fertigation-fertilization via irrigation systems including fully automated and controlled systems; and (v) precision fertilization in large scale farming systems. The paper describes the approaches and their action mechanisms and examines their agronomic and environmental significance. The relevance of the approaches for different farming scales, levels of agronomic intensification and agro-technical sophistication is examined as well.

  8. Chinese culture and fertility decline.

    Science.gov (United States)

    Wu, C; Jia, S

    1992-01-01

    Coale has suggested that cultural factors exert a significant influence on fertility reduction; countries in the "Chinese cultural circle" would be the first to show fertility decline. In China, the view was that traditional Chinese culture contributed to increased population. This paper examines the nature of the relationship between Chinese culture and fertility. Attention was directed to a comparison of fertility rates of developing countries with strong Chinese cultural influence and of fertility within different regions of China. Discussion was followed by an explanation of the theoretical impact of Chinese culture on fertility and direct and indirect beliefs and practices that might either enhance or hinder fertility decline. Emigration to neighboring countries occurred after the Qing dynasty. Fertility after the 1950s declined markedly in Japan, Singapore, Hong Kong, South Korea, Taiwan, and mainland China: all countries within the Chinese cultural circle. Other countries within the Chinese circle which have higher fertility, yet lower fertility than other non-Chinese cultural countries, are Malaysia, Thailand, and Indonesia. Within China, regions with similar fertility patterns are identified as coastal regions, central plains, and mountainous and plateau regions. The Han ethnic group has lower fertility than that of ethnic minorities; regions with large Han populations have lower fertility. Overseas Chinese in East Asian countries also tend to have lower fertility than their host populations. Chinese culture consisted of the assimilation of other cultures over 5000 years. Fertility decline was dependent on the population's desire to limit reproduction, favorable social mechanisms, and availability of contraception: all factors related to economic development. Chinese culture affects fertility reduction by affecting reproductive views and social mechanisms directly, and indirectly through economics. Confucianism emphasizes collectivism, self

  9. THE USE OF VOLUNTARY DISCLOSURE IN DETERMINING THE QUALITY OF FINANCIAL STATEMENTS: EVIDENCE FROM THE NIGERIA LISTED COMPANIES

    Directory of Open Access Journals (Sweden)

    Oyerogba Ezekiel Oluwagbemiga

    2014-10-01

    Full Text Available The purpose of this study was to establish the use of voluntary disclosure in determining the quality of financial statements among the listed companies in Nigeria. Specifically the study investigated on the effects of voluntary disclosure on investor decision and performance of listed companies in Nigeria. This study adopted anexploratory design which is described as a method of collecting information by interviewing or administering a questionnaire to a sample of individuals. The instrument of data collection for this research was a questionnaire as the study used primary data. The study targeted all the 258 listed companies in Nigeria. The study population used in this research comprised of preparers (accountants, external auditors and users of accounting information (financial analysts, stockbrokers, bankers, regulators and educators. The sample of this study was 140 whereby twenty questionnaires were distributed in every category of the respondents.Descriptive statistics such as mode, median, mean, standard deviation, etc were used to perform data analysis. These measures were calculated using Statistical Package for the Social Sciences (SPSS 20 software. SPSS tool (Statistical Package for the Social Sciences was used to organize and analyze data. The study findings indicated that there was increased performance and investor decision making was easy to makedue to voluntary disclosure. The results indicate that voluntary disclosurewas satisfactory in explaining investor decision making and performance of listed companies. It was possible to conclude from the study findings that voluntary disclosure was statistically significant in explaining investor’s decision and performance of listed companies in Nigeria. It was also possible to conclude that there was high level of voluntary disclosure in Nigeria listed firms which led to high performance of the firms and made it easy for investors to make decision whether to invest in the companies or

  10. Voluntary work organization in higher educational establishment: theory and practice

    Directory of Open Access Journals (Sweden)

    Sergey V. Polatayko

    2011-01-01

    Full Text Available The article analyses basic questions of voluntary work formation in higher educational establishment, its conceptual and legislative basis, defines basic directions of students agencies activities and forms of their participation in higher educational establishment activities.

  11. Respiratory inductance plethysmography is suitable for voluntary hyperventilation test.

    Science.gov (United States)

    Calabrese, Pascale; Besleaga, Tudor; Eberhard, André; Vovc, Victor; Baconnier, Pierre

    2007-01-01

    The aim of this work was to evaluate the goodness of fit of a signal issued of the respiratory inductance plethysmography (RIP) derivative to the airflow signal during rest, voluntary hyperventilation, and recovery. RIP derivative signal was filtered with an adjusted filter based on each subject airflow signal (pneumotachography). For each subject and for each condition (rest, voluntary hyperventilation, and recovery) comparisons were performed between the airflow signal and the RIP derivative signal filtered with an adjusted filter obtained either on rest signal or on the studied part of the signals (voluntary hyperventilation or recovery). Results show that the goodness of fit was : (1) higher than 90% at almost all comparisons (122 on 132), (2) not improved by applying an adjusted filter obtained on the studied part of the signals. These results suggest that RIP could be used for studying breathing during voluntary hyperventilation and recovery using adjusted filters obtained from comparison to airflow signal at rest.

  12. Improving Voluntary Environmental Management Programs: Facilitating Learning and Adaptation

    Science.gov (United States)

    Genskow, Kenneth D.; Wood, Danielle M.

    2011-05-01

    Environmental planners and managers face unique challenges understanding and documenting the effectiveness of programs that rely on voluntary actions by private landowners. Programs, such as those aimed at reducing nonpoint source pollution or improving habitat, intend to reach those goals by persuading landowners to adopt behaviors and management practices consistent with environmental restoration and protection. Our purpose with this paper is to identify barriers for improving voluntary environmental management programs and ways to overcome them. We first draw upon insights regarding data, learning, and adaptation from the adaptive management and performance management literatures, describing three key issues: overcoming information constraints, structural limitations, and organizational culture. Although these lessons are applicable to a variety of voluntary environmental management programs, we then present the issues in the context of on-going research for nonpoint source water quality pollution. We end the discussion by highlighting important elements for advancing voluntary program efforts.

  13. Assessing voluntary muscle activation with the twitch interpolation technique.

    Science.gov (United States)

    Shield, Anthony; Zhou, Shi

    2004-01-01

    The twitch interpolation technique is commonly employed to assess the completeness of skeletal muscle activation during voluntary contractions. Early applications of twitch interpolation suggested that healthy human subjects could fully activate most of the skeletal muscles to which the technique had been applied. More recently, however, highly sensitive twitch interpolation has revealed that even healthy adults routinely fail to fully activate a number of skeletal muscles despite apparently maximal effort. Unfortunately, some disagreement exists as to how the results of twitch interpolation should be employed to quantify voluntary activation. The negative linear relationship between evoked twitch force and voluntary force that has been observed by some researchers implies that voluntary activation can be quantified by scaling a single interpolated twitch to a control twitch evoked in relaxed muscle. Observations of non-linear evoked-voluntary force relationships have lead to the suggestion that the single interpolated twitch ratio can not accurately estimate voluntary activation. Instead, it has been proposed that muscle activation is better determined by extrapolating the relationship between evoked and voluntary force to provide an estimate of true maximum force. However, criticism of the single interpolated twitch ratio typically fails to take into account the reasons for the non-linearity of the evoked-voluntary force relationship. When these reasons are examined, it appears that most are even more challenging to the validity of extrapolation than they are to the linear equation. Furthermore, several factors that contribute to the observed non-linearity can be minimised or even eliminated with appropriate experimental technique. The detection of small activation deficits requires high resolution measurement of force and careful consideration of numerous experimental details such as the site of stimulation, stimulation intensity and the number of interpolated

  14. Voluntary reaction time and long-latency reflex modulation.

    Science.gov (United States)

    Forgaard, Christopher J; Franks, Ian M; Maslovat, Dana; Chin, Laurence; Chua, Romeo

    2015-12-01

    Stretching a muscle of the upper limb elicits short (M1) and long-latency (M2) reflexes. When the participant is instructed to actively compensate for a perturbation, M1 is usually unaffected and M2 increases in size and is followed by the voluntary response. It remains unclear if the observed increase in M2 is due to instruction-dependent gain modulation of the contributing reflex mechanism(s) or results from voluntary response superposition. The difficulty in delineating between these alternatives is due to the overlap between the voluntary response and the end of M2. The present study manipulated response accuracy and complexity to delay onset of the voluntary response and observed the corresponding influence on electromyographic activity during the M2 period. In all active conditions, M2 was larger compared with a passive condition where participants did not respond to the perturbation; moreover, these changes in M2 began early in the appearance of the response (∼ 50 ms), too early to be accounted for by voluntary overlap. Voluntary response latency influenced the latter portion of M2, with the largest activity seen when accuracy of limb position was not specified. However, when participants aimed for targets of different sizes or performed movements of various complexities, reaction time differences did not influence M2 period activity, suggesting voluntary activity was sufficiently delayed. Collectively, our results show that while a perturbation applied to the upper limbs can trigger a voluntary response at short latency (reflex gain modulation remains an important contributor to EMG changes during the M2 period. Copyright © 2015 the American Physiological Society.

  15. Voluntary "involuntary" commitment--the briar-patch syndrome.

    Science.gov (United States)

    Miller, R D

    1980-01-01

    Szasz and others have pointed out that many so-called voluntary admissions to mental hospitals have various elements of coercion involved, and are thus not truly voluntary. The author contends that the converse situation is also true, that many patients admitted under involuntary commitment papers arrange for their own commitments. Reasons for such choices are discussed in the context of a review of the literature and several case histories.

  16. Voluntary euthanasia under control? Further empirical evidence from The Netherlands.

    Science.gov (United States)

    Jochemsen, H; Keown, J

    1999-01-01

    Nineteen ninety-six saw the publication of a major Dutch survey into euthanasia in the Netherlands. This paper outlines the main statistical findings of this survey and considers whether it shows that voluntary euthanasia is under effective control in the Netherlands. The paper concludes that although there has been some improvement in compliance with procedural requirements, the practice of voluntary euthanasia remains beyond effective control. PMID:10070633

  17. Students' vocational choices and voluntary action: A 12-nation study

    OpenAIRE

    Haski-Leventhal, Debbie; Cnaan, Ram; Handy, Femida; Brudney, Jeffrey; Holmes, Kirsten; Hustinx, Lesley; Kang, ChulHee; Kassam, Meenaz; Meijs, Lucas; Ranade, Bhagyashree; Yamauchi, Naoto; Yeung, Anne Birgitta; Zrinscak, Sinisa

    2008-01-01

    textabstractPrevious research on student involvement suggested that business and engineering students manifest lowest rates of voluntary action. Similarly, it was thought that social science students are the most involved in voluntary action, with students of natural sciences and humanities in the middle. However, there were very few studies that empirically compared these assertions. Furthermore, these assertions were not investigated from cross-cultural perspectives. Based on a study of stu...

  18. The We and the I: The Logic of Voluntary Associations

    OpenAIRE

    Melnik, Ekaterina; Zimmermann, Jean-Benoît

    2015-01-01

    This paper sheds new light on the economic logic of voluntary associations and the relationship between individual contribution and collective action. The aims are twofold. Firstly, we seek to explain how "team reasoning" (Bacharach et al. 2006) can deeply change the functioning of voluntary associations (which are considered to produce a public good) when some or all of the individual members group together to make collective decisions about their involvement or contribution, rather than dec...

  19. Development of the knowledge of fertility and fertility preservation scale

    Directory of Open Access Journals (Sweden)

    McNees P

    2012-04-01

    Full Text Available Angela Jukkala1, Karen Meneses1, Andres Azuero1, June Cho1, Patrick McNees1,21School of Nursing, 2School of Health Professions, University of Alabama at Birmingham, Birmingham, AL, USAObjective: Infertility is a severe and often underestimated consequence of successful treatment for breast cancer. Ensuring young breast cancer survivors receive patient-centered health information on the impact of treatment on fertility and fertility preservation options in a timely manner is a critical component of high quality nursing care. The objective of this manuscript is to report the process used to develop and examine the reliability and validity of an instrument to measure a breast cancer survivor’s self-assessed knowledge of fertility and fertility preservation.Design: A scale development and descriptive study.Setting: Online and global.Participants: Ninety-two young breast cancer survivors (ages 25–45 years.Methods: Participants completed the Knowledge of Fertility and Fertility Preservation (KF Scale as part of their participation in a larger study, the Fertility Cancer Project (FCP.Results: An exploratory factor analysis revealed five domains: normal reproductive function; general information about fertility; cancer treatment factors affecting fertility; infertility information; and alternative parenting options. A confirmatory factor analysis confirmed the validity of the construct with a demonstrated good fit between the factor structure of the new scale and the observed data. Many participants self-assessed their overall knowledge of fertility and fertility preservation as “a little” and the majority rated their knowledge of infertility information as “a little”.Conclusion: The KF Scale can be used to provide useful information to support health care professionals in the development of patient-centered education that is responsive to the unique needs of each young breast cancer survivor. The initial testing of the KF Scale indicates

  20. Interaction of poststroke voluntary effort and functional neuromuscular electrical stimulation.

    Science.gov (United States)

    Makowski, Nathaniel; Knutson, Jayme; Chae, John; Crago, Patrick

    2013-01-01

    Functional electrical stimulation (FES) may be able to augment functional arm and hand movement after stroke. Poststroke neuroprostheses that incorporate voluntary effort and FES to produce the desired movement must consider how forces generated by voluntary effort and FES combine, even in the same muscle, in order to provide an appropriate level of stimulation to elicit the desired assistive force. The goal of this study was to determine whether the force produced by voluntary effort and FES add together independently of effort or whether the increment in force depends on the level of voluntary effort. Isometric force matching tasks were performed under different combinations of voluntary effort and FES. Participants reached a steady level of force, and while attempting to maintain a constant effort level, FES was applied to augment the force. Results indicate that the increment in force produced by FES decreases as the level of initial voluntary effort increases. Potential mechanisms causing the change in force output are proposed, but the relative contribution of each mechanism is unknown.

  1. Research on Effect of α-secretase on Regulating Hippocampal APP and Aβ42 in APP/PS1 Transgenic Mice of Alzheimer’s disease after Voluntary Wheel Running%α-分泌酶在自主运动调节APP/PS1转基因小鼠海马APP与Aβ42中的作用研究

    Institute of Scientific and Technical Information of China (English)

    余锋; 徐波; 季浏

    2016-01-01

    目的:探讨α-分泌酶在16周自主跑轮运动调节 APP/PS1转基因小鼠海马 APP水解与Aβ42生成中的作用。方法:24只C57系 APP/PS1转基因小鼠,随机分为自主跑轮运动组(TE ,n=12)和对照组(TC ,n=12);同时选取C57系野生型小鼠24只,随机分为自主跑轮运动组(E ,n=12)和对照组(C ,n=12)。 TE组和 E组小鼠从3月龄开始,除给予正常饮食、饮水外,给予16周的自主跑轮运动,TC组和C组小鼠给予正常饮食、饮水,不运动。采用实时荧光定量RT-PCR实验检测各组小鼠海马α-分泌酶家族的3种主要成员ADAM 9、ADAM10和 ADAM17 mRNA表达水平,采用Western Blot实验检测各组小鼠海马 APP、AD-AM 10和 Aβ42蛋白表达水平。结果:1)16周的自主跑轮运动极显著性上调了 APP/PS1转基因小鼠海马 ADAM 10 mRNA表达水平( P<0.01),同时显著性上调了转基因小鼠海马ADAM10蛋白表达水平(P<0.05);2)16周的自主跑轮运动显著上调了 APP/PS1转基因小鼠海马 ADAM17 mRNA 表达水平(P<0.05);3)16周的自主跑轮运动显著性下调了APP/PS1转基因小鼠海马APP ( P<0.05)和Aβ42( P<0.05)的蛋白表达水平。结论:16周的自主跑轮运动可通过促进APP/PS1转基因小鼠海马α-分泌酶基因表达进而降低转基因小鼠海马 APP的水平,并抑制 APP水解产生Aβ42的水平。%Objective :To observe the effect of α-secretase on the hippocampal APP cleaving and Aβ42 deposition in transgenic mice of Alzheimer ’ s disease (AD ) after 16 weeks voluntary wheel running .Methods :24 male APP/PS1 transgenic mice of line C57 that expresses human mutant APP and PS1 in the brain were chosen and divided into wheel running group (TE ,n=12) and control group (TC ,n= 12) .Meanwhile ,24 male wild-type mice in line C57 were chose and divided into wheel running group (E ,n= 12) and control group (C ,n

  2. Voluntary sodium ingestion in wild-type and oxytocin knockout mice.

    Science.gov (United States)

    Vollmer, Regis R; Cai, Hou-Ming; Miedlar, Julie A; Amico, Janet A

    2013-01-01

    Oxytocin knockout (OT KO) mice acutely consume inappropriate amounts of sodium following overnight water deprivation suggesting that oxytocinergic neurons inhibit excessive sodium ingestion (Amico JA, Morris M, Vollmer RR. Mice deficient in oxytocin manifest increased saline consumption following overnight fluid deprivation. Am J Physiol - Regul Integr Comp Physiol 2001; 281:R1368-R1373). This study sought to determine whether oxytocin (OT) provides long-term regulation of voluntary sodium ingestion. Wild-type (WT) and oxytocin knockout male mice were provided choices between diets or drinking solutions that differed in their sodium content. Mice were given access for 1 week to two diets, one containing low sodium (0.01% sodium chloride [NaCl]) content and a second containing a normal sodium (1.0% NaCl) content. During the second week, the animals were given a choice between a low sodium diet and a high sodium (8.0% NaCl) diet. In the second week, mice consumed 4 times more sodium; however, there were no differences between WT and OT KO mice. In a second experiment, mice had access to a two-bottle choice of tap water and a 0.5 M NaCl solution made palatable by the addition of a 4.1% Intralipid emulsion. Both genotypes consumed large, but equivalent, volumes of the Intralipid/sodium solution. The ingestion of this sodium-rich solution stimulated thirst and enhanced the intake of water. Thus, the availability of palatable sodium-rich food or solutions can lead to excessive voluntary sodium ingestion. Compared with oxytocin knockout mice, enhanced voluntary ingestion of sodium-rich solid and liquid diets proceeded unimpeded in WT mice. Therefore, OT pathways may not be essential for regulating solute intake in this setting.

  3. Comparison of body-powered voluntary opening and voluntary closing prehensor for activities of daily life

    Directory of Open Access Journals (Sweden)

    Kelsey Berning

    2014-05-01

    Full Text Available Persons with an upper-limb amputation who use a body-powered prosthesis typically control the prehensor through contralateral shoulder movement, which is transmitted through a Bowden cable. Increased cable tension either opens or closes the prehensor; when tension is released, some passive element, such as a spring, returns the prehensor to the default state (closed or open. In this study, we used the Southampton Hand Assessment Procedure to examine functional differences between these two types of prehensors in 29 nondisabled subjects (who used a body-powered bypass prosthesis and 2 persons with unilateral transradial amputations (who used a conventional body-powered device. We also administered a survey to determine whether subjects preferred one prehensor or the other for specific tasks, with a long-term goal of assessing whether a prehensor that could switch between both modes would be advantageous. We found that using the voluntary closing prehensor was 1.3 s faster (p = 0.02 than using the voluntary opening prehensor, across tasks, and that there was consensus among subjects on which types of tasks they preferred to do with each prehensor type. Twenty-five subjects wanted a device that could switch between the two modes in order to perform particular tasks.

  4. Hedonic value of intentional action provides reinforcement for voluntary generation but not voluntary inhibition of action.

    Science.gov (United States)

    Parkinson, Jim; Haggard, Patrick

    2013-12-01

    Intentional inhibition refers to stopping oneself from performing an action at the last moment, a vital component of self-control. It has been suggested that intentional inhibition is associated with negative hedonic value, perhaps due to the frustration of cancelling an intended action. Here we investigate hedonic implications of the free choice to act or inhibit. Participants gave aesthetic ratings of arbitrary visual stimuli that immediately followed voluntary decisions to act or to inhibit action. We found that participants for whom decisions to act produced a strong positive hedonic value for the immediately following visual stimulus made more choices to act than those with weaker hedonic value for action. This finding is consistent with reinforcement learning of action decisions. However, participants who experienced inhibition as generating more positive hedonic value did not choose to inhibit more than other participants. Thus, voluntary inhibition of action did not act as reinforcement for future inhibitory behaviour. Our finding that inhibition of action lacks motivational capacity may explain why self-control is both difficult and limited.

  5. Comparison of body-powered voluntary opening and voluntary closing prehensor for activities of daily life.

    Science.gov (United States)

    Berning, Kelsey; Cohick, Sarah; Johnson, Reva; Miller, Laura Ann; Sensinger, Jonathon W

    2014-01-01

    Persons with an upper-limb amputation who use a body-powered prosthesis typically control the prehensor through contralateral shoulder movement, which is transmitted through a Bowden cable. Increased cable tension either opens or closes the prehensor; when tension is released, some passive element, such as a spring, returns the prehensor to the default state (closed or open). In this study, we used the Southampton Hand Assessment Procedure to examine functional differences between these two types of prehensors in 29 nondisabled subjects (who used a body-powered bypass prosthesis) and 2 persons with unilateral transradial amputations (who used a conventional body-powered device). We also administered a survey to determine whether subjects preferred one prehensor or the other for specific tasks, with a long-term goal of assessing whether a prehensor that could switch between both modes would be advantageous. We found that using the voluntary closing prehensor was 1.3 s faster (p = 0.02) than using the voluntary opening prehensor, across tasks, and that there was consensus among subjects on which types of tasks they preferred to do with each prehensor type. Twenty-five subjects wanted a device that could switch between the two modes in order to perform particular tasks.

  6. Neuronal correlates of voluntary facial movements.

    Science.gov (United States)

    Krippl, Martin; Karim, Ahmed A; Brechmann, André

    2015-01-01

    Whereas the somatotopy of finger movements has been extensively studied with neuroimaging, the neural foundations of facial movements remain elusive. Therefore, we systematically studied the neuronal correlates of voluntary facial movements using the Facial Action Coding System (FACS, Ekman et al., 2002). The facial movements performed in the MRI scanner were defined as Action Units (AUs) and were controlled by a certified FACS coder. The main goal of the study was to investigate the detailed somatotopy of the facial primary motor area (facial M1). Eighteen participants were asked to produce the following four facial movements in the fMRI scanner: AU1+2 (brow raiser), AU4 (brow lowerer), AU12 (lip corner puller) and AU24 (lip presser), each in alternation with a resting phase. Our facial movement task induced generally high activation in brain motor areas (e.g., M1, premotor cortex, supplementary motor area, putamen), as well as in the thalamus, insula, and visual cortex. BOLD activations revealed overlapping representations for the four facial movements. However, within the activated facial M1 areas, we could find distinct peak activities in the left and right hemisphere supporting a rough somatotopic upper to lower face organization within the right facial M1 area, and a somatotopic organization within the right M1 upper face part. In both hemispheres, the order was an inverse somatotopy within the lower face representations. In contrast to the right hemisphere, in the left hemisphere the representation of AU4 was more lateral and anterior compared to the rest of the facial movements. Our findings support the notion of a partial somatotopic order within the M1 face area confirming the "like attracts like" principle (Donoghue et al., 1992). AUs which are often used together or are similar are located close to each other in the motor cortex.

  7. Neuronal correlates of voluntary facial movements

    Directory of Open Access Journals (Sweden)

    Martin eKrippl

    2015-10-01

    Full Text Available Whereas the somatotopy of finger movements has been extensively studied with neuroimaging, the neural foundations of facial movements remain elusive. Therefore, we systematically studied the neuronal correlates of voluntary facial movements using the Facial Action Coding System (FACS,Ekman et al., 2002. The facial movements performed in the MRI scanner were defined as Action Units (AUs and were controlled by a certified FACS coder. The main goal of the study was to investigate the detailed somatotopy of the facial primary motor area (facial M1. Eighteen participants were asked to produce the following four facial movements in the fMRI scanner: AU1+2 (brow raiser, AU4 (brow lowerer, AU12 (lip corner puller and AU24 (lip presser, each in alternation with a resting phase.Our facial movement task induced generally high activation in brain motor areas (e.g. M1, premotor cortex, SMA, putamen, as well as in the thalamus, insula and visual cortex. BOLD activations revealed overlapping representations for the four facial movements. However, within the activated facial M1 areas, we could find distinct peak activities in the left and right hemisphere supporting a rough somatotopic upper to lower face organization within the right facial M1 area, and a somatotopic organization within the right M1 upper face part. In both hemispheres, the order was an inverse somatotopy within the lower face representations. In contrast to the right hemisphere, in the left hemisphere the representation of AU 4 was more lateral and anterior compared to the rest of the facial movements. Our findings support the notion of a partial somatotopic order within the M1 face area confirming the like attracts like principle (Donoghue et al., 1992 . AUs which are often used together or are similar are located close to each other in the motor cortex.

  8. Cortical potentials associated with voluntary mandibular movements.

    Science.gov (United States)

    Yoshida, K; Kaji, R; Hamano, T; Kohara, N; Kimura, J; Shibasaki, H; Iizuka, T

    2000-07-01

    Movement-related cortical potentials (MRCPs) are negative potentials over the scalp, which gradually increase prior to voluntary movements, and might be applied to elucidate the cortical efferent function of the mandibular movements. We compared the MRCPs accompanying various mandibular movements to study the motor control mechanism underlying these movements. Electroencephalograms (EEGs) were recorded from 11 electrodes placed over the scalp (F3, Fz, F4, T3, C3, Cz, C4, T4, P3, Pz, and P4), according to the International 10-20 System, and electromyograms (EMGs) were obtained from surface electrodes over the masseter muscle and the anterior belly of the digastric muscle. Ten healthy subjects were requested to make brisk and self-paced mandibular movements in 4 different directions (mouth-opening and -closing, and left and right lateral movements). We obtained MRCPs by averaging the EEG, using the visually determined EMG onset as a trigger signal. In all the movements, a slowly increasing, bilaterally widespread negativity starting 1.5 to 2.0 sec before the EMG onset (Bereitschaftspotential, or BP proper) was observed, with the maximum over the vertex region. The negative slope (NS') occurred about 300 to 700 msec before the EMG onset. The cortical maps of BP/NS' (BP and NS' combined), immediately prior to the mouth-opening and closing, showed a symmetrical distribution, whereas that for the lateral movements showed a tendency of predominance over the hemisphere ipsilateral to the direction of the movement. BP/NS' amplitudes at the onset of movement differed significantly or tended to do so between open, close, and lateral movements, suggesting that MRCP recordings may thus provide a means to explore the role of the cerebral cortex in the control of mandibular movements.

  9. Voluntary organizations in development in South Asia.

    Science.gov (United States)

    Maloney, C

    1987-01-01

    The governments of South Asian countries have become aware of the substantial role that nongovernment organizations (NGOs) or voluntary agencies can play in rural development and other nation building activities. Although private agencies cannot substitute for government programs, there is general consensus that NGOs use development funds more efficiently and innovatively than government programs. NGOs in Bangladesh, India, and Pakistan exemplify the influence these organizations have on development in South Asia. The Lutheran World Service in Bangladesh, a foreign origin NGO, has branched out from its original aim of providing relief and war rehabilitation to give skills training and technical assistance to the poor. The Bangladesh Rural Advancement Committee, an indigenous NGO, works for the well-being and self-reliance of the landless poor, those with very small farms, and women. NGOs in Bangladesh have been especially innovative in developing methods to encourage self-help, such as local organization and credit, which are often combined with training in practical skills, literacy, nutrition, and family planning. Present NGO activity in India is dominated by the Gandhian tradition. There is a potential conflict between the philosophy of the NGO's in terms of building on the people's felt needs from the bottom up and the tendency of government agencies to want to plan for the people. In Pakistan, the concept of development-oriented NGOs is recent and not yet strong, although the government has adopted a policy of routing funds from government and from bilateral donor agencies through NGOs in 2 areas--family planning and women's welfare. The chief limitation of NGOs is their scope, meaning that the major burden of the development process rests on government agencies.

  10. Effects of Different Water and Fertilizer Regulations on Leaf Enzyme Activities and Physiological Indexes in Adversity of Maize%不同水肥调控对玉米叶片酶活性及逆境生理指标的影响

    Institute of Scientific and Technical Information of China (English)

    刘树堂; 宋希云; 况川; 曹培顺; 王飞; 姜雯; 裴玉贺

    2015-01-01

    To further explore the theoretical basis of scientific and reasonable water and fertilizer meas-ures on maize production,2 irrigation levels,W1 (2 250 m3 /hm2 )and W2 (4 500 m3 /hm2 ),and 4 fertiliza-tion programs,CK(no fertilizer),NF (conventional fertilization),SF (controlled release fertilizer)and MF (self -made fertilizer),were set to study the effects of 8 treatments on the activities of leaf enzymes (SOD, POD,CAT)and physiological indexes in adversity(Pro,MDA).The results showed that the leaf SOD and CAT activity had the consistent change trend during the whole growth period and reached the highest at the sil-king stage (individual treatment at the filling stage),followed by a sharp decline.The activity of POD had the similar trend with a slow fall.At the same irrigation level,the CAT,SOD activities under SF treatment were significantly higher than those of NF and MF treatments,and the effect of fertilization on POD activity was not significant.The Pro content treated with W1 was the highest at the bell stage,that treated with W2 was the highest at the silking stage and it was more affected by moisture than fertilizer.The optimum model of water and fertilizer regulation for maize was W2 with SF.%为进一步探讨科学合理的水肥措施对玉米生产影响的理论基础,本试验设置了 W1(2250 m3/hm2)与 W2(4500 m3/hm2)两个灌水水平和不施肥(CK)、常规施肥(NF)、施控释肥(SF)与自配复混肥(MF)4个施肥水平,共8个处理,研究其对玉米叶片酶(SOD、POD、CAT)活性及逆境生理指标(Pro、MDA)的影响。结果表明:全生育期玉米叶片 SOD、CAT 活性趋势一致,多在吐丝期(个别处理在灌浆期)达到最高,随后急剧下降,POD 活性趋势与之相近,但后期降幅较缓;相同灌水水平下,施控释肥(SF)的 CAT、SOD 活性显著高于 NF(常规施肥)与 MF(自配复混肥),POD 活性受施肥影响不显著

  11. Design and Experiment of Slave Computer Control System for Applying Variable-rate Liquid Fertilizer

    Institute of Scientific and Technical Information of China (English)

    Zhang Ying-zi; Chen Hai-tao; Hou Shou-yin; Ji Wen-yi; Ouyang Bin-lin; Dun Guo-qiang; Zhang Ji-cheng

    2015-01-01

    In order to increase the applying rate of liquid fertilizer and reduce environmental pollution, a slave computer control system for applying variable-rate liquid fertilizer was designed. The system used SMC as core processor and electrically controlled pressure regulator as execution component. The characteristic equation of the system was obtained by using classical control theory. Results indicated that the characteristic equation met the requirements of routh-criterion, which indicated the working process of the system was stable. Performance of the slave computer was verified via bench tests. Results demonstrated that there was no significant influence on the response from interclass error. The fertilization error was less than 0.9, and the fertilization accuracy was larger than 97%. The liquid fertilizer emitted by the fertilizing devices had no significant difference in uniformity, which met the demands of the slave computer control system for applying variable-rate liquid fertilizer.

  12. Fertility as a process of social exchange

    Directory of Open Access Journals (Sweden)

    Patrick Heady

    2007-12-01

    Full Text Available By marrying and raising children, parents participate in a system of gift-exchange in which the gifts in question are human lives, and the parties to the exchange are the kinship groups recognised in the society concerned. Fertility reflects the attitudes of prospective parents to their place in the existing system of reproductive exchange, and the relationships of cooperation and authority which it implies - as well as their confidence in the system's continuing viability. It is shown that this view is compatible with earlier ideas about self-regulating population systems - and that changing economic circumstances are an important source of discrepancy between existing exchange systems and the attitudes and expectations of prospective parents. The discussion is developed with reference to data on European societies, including a case-study from the Alps, and concludes with an assessment of the relevance of the anthropological theory of gift exchange to contemporary fertility patterns in Europe and beyond.

  13. DEVELOPMENT OF MICROFLORA IN APPLE ROOT RHIZOSPERE WHEN FERTILIZING

    Directory of Open Access Journals (Sweden)

    Kuzin A. I.

    2015-09-01

    Full Text Available The problem of environmental safety of agricultural products and agro-technical measures is very urgent now. Various agrochemicals are widely used in agricultural production: plant protection preparations, fertilizers, stimulants and plant growth regulators, etc. One possible solution of this problem may be a partial replacement of mineral fertilizers by bacterial ones. The aim of our research was to determine the effect of different fertilizers and methods of their application on the quantity of microorganisms in the apple root rhizosphere soil. The research was carried out according to conventional methods. In our experiment, we determined the number of microorganisms in the rhizosphere of the roots of apple trees, nitrogen, phosphorus and potassium in the leaves; hydrolysable nitrogen, available phosphorus and exchangeable potassium in soil and crop yield. The highest yield was obtained by fertigation in our research. Application bacterial fertilizer to the soil ensured yield increase at the level of mineral fertilizer application. Application of fertilizers in general, in the studied application rates provided optimum level of nitrogen, phosphorus and potassium content in the leaves and soil. By use of fertigation and bacterial fertilizers were high and relatively stable numbers of microorganisms in the rhizosphere of the apple trees. The number of microorganisms in the rhizosphere had a positive correlation with yield and the content of nutrients in soil and in leaves

  14. Temporal Trends in Fertility Rates

    DEFF Research Database (Denmark)

    Jensen, Martin Blomberg; Priskorn, Lærke; Jensen, Tina Kold

    2015-01-01

    to determine total and age specific fertility rates. RESULTS: Total fertility rate (TFR) decreased from 4.1 to 1.8 children per woman and age specific fertility also decreased from 1901 to 2014. Women aged 30-34, 35-39 or 40-44 years in the first decade of the 20th century had higher fertility rates than......OBJECTIVE: Increasing age at first childbirth has been suggested to increase the risk for infertility. Our objective is to determine whether women above thirty years of age historically have been able to sustain fertility rates above replacement level. DESIGN: A descriptive nationwide Danish study...... for 10% of TFR in 1901 compared with 4% in 2014 despite usage of assisted reproduction. CONCLUSION: This nationwide study shows that women above 30 years of age historically have been able to sustain fertility rates above replacement level. This implies that other factors besides age are strong...

  15. Fertility and age

    Directory of Open Access Journals (Sweden)

    Korula George

    2010-01-01

    Full Text Available The changing social scenario together with economic growth and an increase in job opportunities has to a great extent reduced gender inequality and has resulted in more and more older women seeking help from infertility clinics. Fertility and aging have always been closely linked and the age of the female partner remains the single most important factor in predicting success with treatment. Although tests for the ovarian reserve are an important informative tool and are helpful in selecting treatment options, they are poor predictors of the outcome.

  16. WILL FERTILITY REBOUND IN JAPAN

    OpenAIRE

    Creina Day

    2012-01-01

    Fertility and per capita income are now positively associated across most high income OECD countries. Low fertility and a gender wage gap persist in Japan. This paper presents an original model where endogenous increases in childcare prices and gender equity in capital allocation play important roles in the effect of per capita income growth and rising female relative wages on fertility. Results suggest Japan has cause for optimism. Economic growth will raise female relative wages where capit...

  17. Opt-out HIV testing in prison: informed and voluntary?

    Science.gov (United States)

    Rosen, David L; Golin, Carol E; Grodensky, Catherine A; May, Jeanine; Bowling, J Michael; DeVellis, Robert F; White, Becky L; Wohl, David A

    2015-01-01

    HIV testing in prison settings has been identified as an important mechanism to detect cases among high-risk, underserved populations. Several public health organizations recommend that testing across health-care settings, including prisons, be delivered in an opt-out manner. However, implementation of opt-out testing within prisons may pose challenges in delivering testing that is informed and understood to be voluntary. In a large state prison system with a policy of voluntary opt-out HIV testing, we randomly sampled adult prisoners in each of seven intake prisons within two weeks after their opportunity to be HIV tested. We surveyed prisoners' perception of HIV testing as voluntary or mandatory and used multivariable statistical models to identify factors associated with their perception. We also linked survey responses to lab records to determine if prisoners' test status (tested or not) matched their desired and perceived test status. Thirty-eight percent (359/936) perceived testing as voluntary. The perception that testing was mandatory was positively associated with age less than 25 years (adjusted relative risk [aRR]: 1.45, 95% confidence interval [CI]: 1.24, 1.71) and preference that testing be mandatory (aRR: 1.81, 95% CI: 1.41, 2.31) but negatively associated with entry into one of the intake prisons (aRR: 0.41 95% CI: 0.27, 0.63). Eighty-nine percent of prisoners wanted to be tested, 85% were tested according to their wishes, and 82% correctly understood whether or not they were tested. Most prisoners wanted to be HIV tested and were aware that they had been tested, but less than 40% understood testing to be voluntary. Prisoners' understanding of the voluntary nature of testing varied by intake prison and by a few individual-level factors. Testing procedures should ensure that opt-out testing is informed and understood to be voluntary by prisoners and other vulnerable populations.

  18. Variable Fertilizer Control System for Deep-fertilization Liquid Fertilizer Applicator%深施型液态肥变量施肥控制系统

    Institute of Scientific and Technical Information of China (English)

    郎春玲; 王金武; 王金峰; 何剑南; 郗晓焕

    2013-01-01

    A control system for variahle rate fertilization, which depends on deep-fertilization liquid fertilizer applicator, was introduced. The single chip microcomputer was used as core processor and electromagnetic proportion regulator valve was used as execution unit. Software was designed for selecting data and sending commands. The test results in the test-bed showed that the system can complete the control of variable rate fertilization and the error of the variable fertilizing was less than 0. 5 mL in each time, which meets the liquid fertilizer variables requirement.%以深施型液态施肥机为依托,采用单片机作为核心处理器,以电磁比例调节阀为执行部件,设计了深施型液态变量施肥控制系统.设计了与硬件配套的上位机软件,用于采集数据与发送命令.喷肥针施肥量控制误差台架试验结果表明,该系统可实现深施型液态变量施肥,施肥误差不超过0.5 mL/次,满足液态变量施肥作业要求.

  19. Circulating levels of endocannabinoids respond acutely to voluntary exercise, are altered in mice selectively bred for high voluntary wheel running, and differ between the sexes.

    Science.gov (United States)

    Thompson, Zoe; Argueta, Donovan; Garland, Theodore; DiPatrizio, Nicholas

    2017-03-01

    The endocannabinoid system serves many physiological roles, including in the regulation of energy balance, food reward, and voluntary locomotion. Signaling at the cannabinoid type 1 receptor has been specifically implicated in motivation for rodent voluntary exercise on wheels. We studied four replicate lines of high runner (HR) mice that have been selectively bred for 81 generations based on average number of wheel revolutions on days five and six of a six-day period of wheel access. Four additional replicate lines are bred without regard to wheel running, and serve as controls (C) for random genetic effects that may cause divergence among lines. On average, mice from HR lines voluntarily run on wheels three times more than C mice on a daily basis. We tested the general hypothesis that circulating levels of endocannabinoids (i.e., 2-arachidonoylglycerol [2-AG] and anandamide [AEA]) differ between HR and C mice in a sex-specific manner. Fifty male and 50 female mice were allowed access to wheels for six days, while another 50 males and 50 females were kept without access to wheels (half HR, half C for all groups). Blood was collected by cardiac puncture during the time of peak running on the sixth night of wheel access or no wheel access, and later analyzed for 2-AG and AEA content by ultra-performance liquid chromatography coupled to tandem mass spectrometry. We observed a significant three-way interaction among sex, linetype, and wheel access for 2-AG concentrations, with females generally having lower levels than males and wheel access lowering 2-AG levels in some but not all subgroups. The number of wheel revolutions in the minutes or hours immediately prior to sampling did not quantitatively predict plasma 2-AG levels within groups. We also observed a trend for a linetype-by-wheel access interaction for AEA levels, with wheel access lowering plasma concentrations of AEA in HR mice, while raising them in C mice. In addition, females tended to have higher AEA

  20. A plant plasma membrane Ca2+ pump is required for normal pollen tube growth and fertilization

    DEFF Research Database (Denmark)

    Schiøtt, Morten; Romanowsky, Shawn M; Bækgaard, Lone

    2004-01-01

    Ca(2+) signals are thought to play important roles in plant growth and development, including key aspects of pollen tube growth and fertilization. The dynamics of a Ca(2+) signal are largely controlled by influx (through channels) and efflux (through pumps and antiporters). The Arabidopsis genome...... and a high frequency of aborted fertilization, resulting in a >80% reduction in seed set. These findings identify a plasma membrane Ca(2+) transporter as a key regulator of pollen development and fertilization in flowering plants....

  1. [The decline of fertility in Western Europe. III. Some considerations on future evolution and on policy measures aiming at supporting fertility (author's transl)].

    Science.gov (United States)

    Calot, G

    1977-06-30

    The analysis of recent fertility trends in France lead to hold as plausible that women born after 1950 will not reach replacement level. On the other hand, the period total fertility rate, which has not fallen as low as those observed in some neighbouring countries, might well continue to decline and thus disturb the alimentation of age-pyramid, despite its slower decrease in the course of 1976. Considering present fertility situation in France, an action of the State appears to be desirable. The factors which condition fertility fall largely out of the range of well-established knowledge. Though, it seems that they are deeply rooted in collective consciousness and that the possibilities they leave to voluntary action on fertility trends is relatively modest. Moreover, to be efficient, the means used must be important. The lines of possible action seem, in our view, to relate to two main fields: research of a better conciliation of professional activity and motherhood, increase of family benefits for second but specially for third and following children.

  2. Fertile ground? : soil fertility management and the African smallholder

    NARCIS (Netherlands)

    Misiko, M.

    2007-01-01

    Keywords: smallholder farmers, soil fertility, experimentation, "inconvenience", realist.The focus in this thesis is to form a view of how well soil fertility research performs within the ever shifting smallholder contexts. This study examined application of agro-ecological knowled

  3. [Voluntary testing procedures of farm animal housing equipment according to the Animal Welfare Act of 1998].

    Science.gov (United States)

    Hesse, D; Knierim, U; von Borell, E; Herrmann, H; Koch, L; Müller, C; Rauch, H W; Sachser, N; Schwabenbauer, K; Zerbe, F

    1999-04-01

    Before its broad application in practice, housing equipment should be tested, in particular with regard to animal welfare. The differing positions of the German Federal Council (Bundesrat) and the German Federal Parliament (Bundestag), whether such testing should be mandatory or voluntary, have been conciliated in the amended animal welfare act by empowering the Federal Ministry of Food, Agriculture and Fisheries (BML) to fix official standards for voluntary testing procedures by regulation. On request of the BML, a report as scientific basis for a draft regulation is currently prepared by the scientific animal welfare committee of the German Agricultural Society (DLG). The scientific animal welfare committee has been appointed by the DLG in order to provide support in the effort to strengthen animal welfare aspects in the DLG-utility testing procedure of housing equipment, which is in place since 1953. The committee elaborates standards concerning testing methods, assessment criteria and the necessary size of investigations. As required, the scientific animal welfare committee may support the DLG-testing bodies in the implementation of the animal welfare part of the testing procedure. It will, moreover, be involved in the welfare assessment based on the testing results. The amendments of the already established testing procedure will help to fulfill the general requirements on an acceptable animal welfare testing procedure. While keeping in mind that there are certain limits in what can be achieved by a voluntary testing procedure, the enhanced consideration of animal welfare aspects within the DLG-utility testing procedure has the advantage to be relatively unbureaucratic and in line with EU legislation, and is, therefore, an appropriate tool for a contibrution to improved animal welfare in livestock housing.

  4. Cancer treatment: fertility and sexual side effects in women

    Science.gov (United States)

    ... Alternative Names Radiotherapy - fertility; Radiation - fertility; Chemotherapy - fertility; Sexual dysfunction - cancer treatment References American Cancer Society. Fertility and women with cancer. Updated November 6, 2013. www.cancer. ...

  5. Redefining RECs: Additionality in the voluntary Renewable Energy Certificate market

    Science.gov (United States)

    Gillenwater, Michael Wayne

    In the United States, electricity consumers are told that they can "buy" electricity from renewable energy projects, versus fossil fuel-fired facilities, through participation in a voluntary green power program. The marketing messages communicate to consumers that their participation and premium payments for a green label will cause additional renewable energy generation and thereby allow them to claim they consume electricity that is absent pollution as well as reduce pollutant emissions. Renewable Energy Certificates (RECs) and wind energy are the basis for the majority of the voluntary green power market in the United States. This dissertation addresses the question: Do project developers respond to the voluntary REC market in the United States by altering their decisions to invest in wind turbines? This question is investigated by modeling and probabilistically quantifying the effect of the voluntary REC market on a representative wind power investor in the United States using data from formal expert elicitations of active participants in the industry. It is further explored by comparing the distribution of a sample of wind power projects supplying the voluntary green power market in the United States against an economic viability model that incorporates geographic factors. This dissertation contributes the first quantitative analysis of the effect of the voluntary REC market on project investment. It is found that 1) RECs should be not treated as equivalent to emission offset credits, 2) there is no clearly credible role for voluntary market RECs in emissions trading markets without dramatic restructuring of one or both markets and the environmental commodities they trade, and 3) the use of RECs in entity-level GHG emissions accounting (i.e., "carbon footprinting") leads to double counting of emissions and therefore is not justified. The impotence of the voluntary REC market was, at least in part, due to the small magnitude of the REC price signal and lack of

  6. Women's education and fertility behaviour.

    Science.gov (United States)

    1993-12-01

    The education of women results in changes in women's health status, family well being, and fertility decline. The aim of human rights and social justice is also served by increasing women's educational levels. A review of the trends in developing countries has shown that there is a strong correlation between advanced female education (10 or more years) and lower fertility. Data for 26 countries was presented in table form for total fertility rates by years of education. There were many differences in the patterns of fertility by educational level based on country level of development. The data appeared to show stronger correlations between fertility and education in more prosperous societies; culture and social structure also influenced fertility. Partial primary education has been shown in some countries to be related to increased fertility. A UN study found a curvilinear relationship between fertility and education in 14 out of 38 countries with World Fertility Surveys. There were only 3 countries with Demographic and Health Surveys which showed the curvilinear pattern. The UN study confirmed that maternal education was related to shorter durations of postpartum abstinence and short durations of lactation. Caution was urged in interpreting that an increase in a few years of schooling in a dominant rural, illiterate population would facilitate rapid fertility decline. A critical threshold effect for educational attainment was found in mainly the least developed countries. Female education has direct and indirect effects on fertility. Education may affect breast feeding patterns, contraceptive use, social norms about small families, later age at marriage, and later age at first birth. The suggestion was that education provided for reproductive choice and reduces the gap between actual and desired family size. At the country and individual level of analysis, contraceptive use was linked with education. Effective contraceptive use was still however impeded by

  7. Market Motivations for Voluntary Carbon Disclosure in Real Estate Industry

    Science.gov (United States)

    Ufere, Kalu Joseph; Alias, Buang; Godwin Uche, Aliagha

    2016-07-01

    Climate change mitigation in developing economies is a balancing act, between economic development and environmental sustainability. The need for market friendly determinants for low carbon economy, without compromising economic development is of essence. The aim of the study is to determine market friendly factors, which motivates voluntary carbon information disclosure, in the real estate industry. The study modeled economic factor with three variables and financial market factor with three variables against voluntary carbon information disclosure in the real estate industry. Structural equation modeling was used for the modeling and content analysis was used to collect data on the level of voluntary carbon information disclosure, from 2013 annual reports of 126 real estate sector companies listed in the Kuala Lumpur Stock Exchange (KLSE). The model achieved a good fit, and was acceptable prediction. The results show that financial market factor has a significant predictive influence on voluntary carbon disclosure. The application of the result is that financial market factor is has a significantly positive influence on companies’ willingness to make voluntary carbon disclosure in the real estate industry. The result may be limited to the real estate industry that is highly leveraged on syndicated fund.

  8. Regulation of 14-3-3 in the First Mitotic Cell Cycle in One-cell Stage Mouse Fertilized Eggs%14-3-3蛋白调节1-细胞期小鼠受精卵有丝分裂

    Institute of Scientific and Technical Information of China (English)

    崔城; 秦鑫; 任秀丽; 于秉治

    2013-01-01

    目的 研究14-3-3蛋白在1-细胞期小鼠受精卵有丝分裂中的作用.方法 RT-PCR技术鉴定小鼠受精卵14-3-3蛋白亚型.采用显微注射方法将14-3-3 siRNA注射入小鼠受精卵G1期,观察受精卵的卵裂率、形态学变化及MPF活性.结果 小鼠受精卵中的14-3-3蛋白亚型是14-3-3ε.小鼠受精卵注射pSUPER-14-3-3ε siRNA后,与对照组相比,卵裂率下降,有丝分裂延迟,有更多的受精卵发生形态异常,MPF活性最高值显著下降.结论 14-3-3蛋白在调节小鼠受精卵有丝分裂中发挥重要作用.%Objective To study the effects of 14-3-3 proteins in regulation of the first mitotic cell cycle in one-cell stage mouse fertilized eggs. Methods 14-3-3 isoform in the mouse fertilized eggs was identified by RT-PCR. 14-3-3 siRNA was introduced to G1 phase fertilized eggs by microinjection to study the cleavage rate, morphology and MPF activity. Results 14-3-3 ε was identified in one-cell stage of mouse fertilized eggs. Compared with the control group,the cleavage rate in pSUPER-14-3-3ε siRNA injection group was significantly decreased, mitosis was delayed and more abnormal morphology eggs were observed. Moreover, the maximal value of MPF activity was significantly decreased. Conclusion 14-3-3 proteins play critical roles in the first mitotic cell cycle in mouse fertilized eggs.

  9. Should Voluntary Services Be Financially Rewarded?

    Institute of Scientific and Technical Information of China (English)

    2010-01-01

    @@ The city of Suqian in east China's Jiangsu Province, put a new regulation into practice six months ago whereby police authorities reward residents who volunteer to make peace in neighborhood quarrels, mediate in civil disputes or, for that matter, help in put-ring out fires.

  10. Should Voluntary Services Be Financially Rewarded?

    Institute of Scientific and Technical Information of China (English)

    2010-01-01

    The city of Suqian in east China’s Jiangsu Province,put a new regulation into practice six months ago whereby police authorities reward residents who volunteer to make peace in neighborhood quarrels,mediate in civil disputes or,for that matter,help in putting out fires.

  11. 22 CFR 127.12 - Voluntary disclosures.

    Science.gov (United States)

    2010-04-01

    ... Foreign Relations DEPARTMENT OF STATE INTERNATIONAL TRAFFIC IN ARMS REGULATIONS VIOLATIONS AND PENALTIES... substantially similar information from another source and commences an investigation or inquiry that involves..., or protection enforceable at law or in equity by any person in any civil, criminal, administrative...

  12. Menstrual cycle pattern and fertility

    DEFF Research Database (Denmark)

    Kolstad, Henrik A.; Bonde, Jens Peter; Hjøllund, Niels Henrik;

    1999-01-01

    To characterize how the menstrual cycle pattern relates to fertility regardless of potential biases caused by inappropriate coital timing during the menstrual cycle or early embryonal loss.......To characterize how the menstrual cycle pattern relates to fertility regardless of potential biases caused by inappropriate coital timing during the menstrual cycle or early embryonal loss....

  13. Family Systems and Fertility Intentions

    NARCIS (Netherlands)

    Mönkediek, Bastian; Bras, Hilde

    2017-01-01

    Family systems, as normative frameworks in which family processes unfold, are believed to exert a major influence on fertility. While a number of studies have addressed family system effects on family size and the timing of births, the question of how family systems influence fertility intentions

  14. ASSESSMENT OF PERCHLORATE IN FERTILIZERS

    Science.gov (United States)

    Perchlorate has been positively detected only in those materials known to be derived from Chilean caliche, which constitute less than 0.2% of U.S. fertilizer application. The data obtained in the preponderance of investigations suggest that fertilizers do not contribute to envir...

  15. Voluntary Running Depreciates the Requirement of Ca[superscript 2+]-Stimulated cAMP Signaling in Synaptic Potentiation and Memory Formation

    Science.gov (United States)

    Zheng, Fei; Zhang, Ming; Ding, Qi; Sethna, Ferzin; Yan, Lily; Moon, Changjong; Yang, Miyoung; Wang, Hongbing

    2016-01-01

    Mental health and cognitive functions are influenced by both genetic and environmental factors. Although having active lifestyle with physical exercise improves learning and memory, how it interacts with the specific key molecular regulators of synaptic plasticity is largely unknown. Here, we examined the effects of voluntary running on long-term…

  16. Neurons controlling voluntary vocalization in the macaque ventral premotor cortex.

    Directory of Open Access Journals (Sweden)

    Gino Coudé

    Full Text Available The voluntary control of phonation is a crucial achievement in the evolution of speech. In humans, ventral premotor cortex (PMv and Broca's area are known to be involved in voluntary phonation. In contrast, no neurophysiological data are available about the role of the oro-facial sector of nonhuman primates PMv in this function. In order to address this issue, we recorded PMv neurons from two monkeys trained to emit coo-calls. Results showed that a population of motor neurons specifically fire during vocalization. About two thirds of them discharged before sound onset, while the remaining were time-locked with it. The response of vocalization-selective neurons was present only during conditioned (voluntary but not spontaneous (emotional sound emission. These data suggest that the control of vocal production exerted by PMv neurons constitutes a newly emerging property in the monkey lineage, shedding light on the evolution of phonation-based communication from a nonhuman primate species.

  17. Suicide and voluntary active euthanasia: why the difference in attitude?

    Science.gov (United States)

    Beech, I

    1995-06-01

    It appears that the attitudes of health professionals differ towards suicide and voluntary active euthanasia. An acceptance of, if not an agreement with, voluntary active euthanasia exists, while there is a general consensus that suicide should be prevented. This paper searches for a working definition of suicide, to discover ethical reasons for the negative value that suicide assumes, and also to provide a term of reference when comparing suicide with euthanasia. On arriving at a working definition of suicide, it is compared with voluntary active euthanasia. An analysis of utilitarian and deontological considerations is provided and proves to be inconclusive with respect to the ethical principles informing the attitudes of professionals. Therefore, a search for other influences is attempted; this indicates that psychological influences inform attitudes to a greater degree than ethical principles.

  18. Propensity for Voluntary Travel Behavior Changes: An Experimental Analysis

    DEFF Research Database (Denmark)

    Meloni, Italo; Sanjust, Benedetta; Sottile, Eleonora;

    2013-01-01

    implementation, which consisted of providing car users with a personalized travel plan after the first week of observation (before) and using the second week to monitoring the post-behavior (after). These data have then been used to estimate a Mixed Logit for the choice to use a personal vehicle or a light metro......In this paper we analyze individual propensity to voluntary travel behavior change combining concepts from theory of change with the methodologies deriving from behavioral models. In particular, following the theory of voluntary changes, we set up a two-week panel survey including soft measure......; and a Multinomial Logit for the decision to change behavior. Results from both models show the relevance of providing information about available alternatives to individuals while promoting voluntary travel behavioral change....

  19. Children Procedures and Treatment (Fertility Issues)

    Medline Plus

    Full Text Available ... approach the subject of fertility preservation with their cancer-stricken child? How is the Oncofertility Consortium addressing the fertility preservation needs of children? How do cancer and cancer treatment affect a child's fertility? Why ...

  20. Children Procedures and Treatment (Fertility Issues)

    Medline Plus

    Full Text Available ... approach the subject of fertility preservation with their cancer-stricken child? How is the Oncofertility Consortium addressing the fertility preservation needs of children? How do cancer and cancer treatment affect a child's fertility? Why ...

  1. Internal fertilization in an oviparous frog.

    Science.gov (United States)

    Townsend, D S; Stewart, M M; Pough, F H; Brussard, P F

    1981-04-24

    Eleutherodactylus coqui, an oviparous frog, undergoes internal fertilization. If this mode of fertilization occurs in other species of anurans, interpretations of anuran reproductive strategies based on the assumption of external fertilization must be reviewed.

  2. Double fertilization in Helianthus

    Directory of Open Access Journals (Sweden)

    J. Telżyńska

    2015-01-01

    Full Text Available After controlled pollination of Helianthus annuus L. florets, the whole course of fertilization is described and documented on 24 microphotos. The timing of events is evaluated. The average cell cycle in the proembryo is 2 hours and the nuclear cycle in endosperm - 60 minutes.Plasmoptysis is suggested as the mechanism of pollen tube opening in the synergid. The structure of the thread-like sperm nucleus is interpreted as an end to end union of chromosomes, and the morphological changes of the sperm nuclei are explained as folding and coiling, based on a spiralization mechanism of chromosomes. Cytochemical observations indicating ribosome formation in the course of the nuclear cycles in the endosperm are described. The mechanisms accelerating nuclear cycles in the endosperm are discussed.

  3. Safety and Effectiveness of Struvite from Black Water and Urine as a Phosphorus Fertilizer

    NARCIS (Netherlands)

    Gell, K.; Ruijter, de F.J.; Kuntke, P.; Graaff, de M.; Smit, A.L.

    2011-01-01

    To ensure food supply, phosphorus must be recycled, for which an appealing method is using struvite fertilizer from human excreta. One struvite from black water and another from urine were assessed for safety under Dutch regulations, and for effectiveness as P fertilizer in a maize field experiment

  4. 激素和施肥处理对麻疯树生长发育的影响%Effects of Plant Growth Regulators and Fertilizer Treatments on the Growth and Development of Jatropha Curcas

    Institute of Scientific and Technical Information of China (English)

    王秀荣; 赵杨; 丁贵杰

    2012-01-01

    [Objective]To understand the effects of foreign matter on flower bud differentiation and nutritive material of Jatropha curcas. [ Method] Different levels of ETH + MET + fertilizer were sprayed on the stem apex with orthogonal test. [ Result ] Medicine combination could promote floral initiation of Jatropha curcas within a certain extent, of which the ETH (600 mg/L) + MET (600 mg/L) + fertilizer( B-Mn) was more significant than others. The tree entered the vegetative stage and reproductive stage in about one month after treatment. The branch sprouted the most numerous buds treated by ETH (600 mg/L) + MET (600 mg/L) + fertilizer(N). As the ETH concentration increased, the new shoots increased in number. [Conclusion] There was significant difference in average weekly growth rate of leaf,ETH and fertilizer were the major factors affecting the growth rate of leaf.%[目的]了解外源物质处理对麻疯树生长及成花的影响.[方法]利用不同浓度的乙烯利、多效唑及3种肥料处理麻疯树茎尖.[结果]该药物组合可以在一定程度上促进麻疯树成花,其中以乙烯利(600 mg/L)+多效唑(600 mg/L)+肥种(B-Mn)促花效果最好,处理后1个月左右是麻疯树进入生殖生长和营养生长活跃时期,以乙烯利(600)+多效唑(600)+肥种(N)组合处理后产生的新梢教最多.在一定范围内,随着乙烯利浓度增高,新梢数有增加的趋势.[结论]各处理组合的叶片增长速度间存在极显著差异,肥种和乙烯利是影响麻疯树叶片增长的主要因子.

  5. Migrant fertility differentials in Ecuador.

    Science.gov (United States)

    Rundquist, F; Brown, L A

    1989-01-01

    The effects of migration on fertility in Ecuador were analyzed by subdividing migrant categories into permanent-, return-, circular-, and non-migrants, and context factors into 6 socioeconomic and agrarian variables. The study is introduced with a conceptual framework that explains personal intermediate variables and their influence on fertility in terms of demographic transition theory, and then defines the influences of selection for fertility, disruption of marital unions, and socialization into fertility norms at the origin vs. assimilation of norms at the destination. Migrants are usually better educated, younger and upwardly mobile, all selecting for lower fertility. Migration disrupts formation of marital unions, and causes separation of spouses, lowering fertility. Data for this study were from the 1974 and 1982 Ecuadorian Population Censuses. The contextual variables analyzed were urban/rural; manufacturing/agricultural; mineral extraction/economic recession; long/recent agricultural settlement; domestic/export crop; and large/medium sized farm. The analysis of personal attributes showed that fertility increased over the range on non-migrants through circular-, return- to permanent-migrants, a finding explained by degrees of disruption of unions. Higher fertility was associated with less education, lower economic participation, higher prevalence of marriage, longer residence and older ages. Regression analysis also showed that personal attributes outweighed contextual factors: thus age, marriage rates, residence time, education and economic activity were significant. Contextual factors were important only for non-migrants, except for destination variables which affected return-migrants and origin variables which affected circular-migrants. Low fertility was associated with urbanization, industrialization, mineral extraction, large farms, recent farm settlement and export crops. The results indicate cear influences of modernity and place influences on

  6. Final voluntary release assessment/corrective action report

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-11-12

    The US Department of Energy, Carlsbad Area Office (DOE-CAO) has completed a voluntary release assessment sampling program at selected Solid Waste Management Units (SWMUs) at the Waste Isolation Pilot Plant (WIPP). This Voluntary Release Assessment/Corrective Action (RA/CA) report has been prepared for final submittal to the Environmental protection Agency (EPA) Region 6, Hazardous Waste Management Division and the New Mexico Environment Department (NMED) Hazardous and Radioactive Materials Bureau to describe the results of voluntary release assessment sampling and proposed corrective actions at the SWMU sites. The Voluntary RA/CA Program is intended to be the first phase in implementing the Resource Conservation and Recovery Act (RCRA) Facility Investigation (RFI) and corrective action process at the WIPP. Data generated as part of this sampling program are intended to update the RCRA Facility Assessment (RFA) for the WIPP (Assessment of Solid Waste Management Units at the Waste Isolation Pilot Plant), NMED/DOE/AIP 94/1. This Final Voluntary RA/CA Report documents the results of release assessment sampling at 11 SWMUs identified in the RFA. With this submittal, DOE formally requests a No Further Action determination for these SWMUs. Additionally, this report provides information to support DOE`s request for No Further Action at the Brinderson and Construction landfill SWMUs, and to support DOE`s request for approval of proposed corrective actions at three other SWMUs (the Badger Unit Drill Pad, the Cotton Baby Drill Pad, and the DOE-1 Drill Pad). This information is provided to document the results of the Voluntary RA/CA activities submitted to the EPA and NMED in August 1995.

  7. Towards State Hegemony Over Agricultural Certification: From Voluntary Private to Mandatory State Regimes on Palm Oil in Indonesia

    Directory of Open Access Journals (Sweden)

    Muhammad Alif Kaimuddin Sahide

    2015-12-01

    Full Text Available Previous work on certification of palm oil has reported on a trend toward a change, from failed state regulation to voluntary, private governance. However, recent observations suggest a trend, moving from voluntary, private governance to mandatory state governance in palm oil certification in Indonesia, a move in which the state is reclaiming authority.In thislight, the aims of ourresearch are (1 to identify the main actorsinvolved in certification politics, (2 to explain this trend in terms of the actors' interests and whatever benefits may result for them. We developed our research questions based on bureaucratic politics and power theory. A mix of document analysis, interviews, and observations are applied for addressing the questions. The results answer our research questions, i.e., that (1 the state claims back its authority over certification from private actors and contributed to the complex meta governance of palm oil certification, the state mandatory scheme that is supported by states' bureaucracies in charge reducesthe influence of non-government or private actors. (2 Thistrend is due to a coalition ofspecific state bureaucracies and big industry interests, which grant privileges to industry that are denied to small producers. Unexpectedly, all Indonesian bureaucracies associated with this trend support mandatory state certification, which indicates that palm oil has been elevated in importance to become a matter of national, rather than mere bureaucratic interest.Making certificationmandatory through coercive regulatory poweristhe main toolwithwhich state power can challenge voluntary implementation and reclaim authority. Furthermore, the state needs the voluntary system to exist as well in order to strengthen its position. Therefore, the voluntary and the compulsory systems collaborate to attract global initiatives,which is contributing to the high complex of meta governance.

  8. Voluntary vs directed siting -- or somewhere in-between?

    Energy Technology Data Exchange (ETDEWEB)

    Peelle, E.B.

    1994-04-01

    Waste siting gridlock in the United States and Canada has led to experimentation with voluntary and hybrid or ``mixed mode`` siting. We review nuclear and hazardous waste voluntary siting (VS) results for selected cases in the U.S, and Canada. Findings indicate that VS is not a panacea, but that current siting efforts are inadequate tests of its potential. We suggest trials of improved VS protocols and more effort on hybrid approaches in which the developer chooses the site but is required to reach agreement on conditions with local stakeholders. Mixed mode siting may be better suited to the US context and its three-tiered governmental system.

  9. The voluntary control of facial action units in adults.

    Science.gov (United States)

    Gosselin, Pierre; Perron, Mélanie; Beaupré, Martin

    2010-04-01

    We investigated adults' voluntary control of 20 facial action units theoretically associated with 6 basic emotions (happiness, fear, anger, surprise, sadness, and disgust). Twenty young adults were shown video excerpts of facial action units and asked to reproduce them as accurately as possible. Facial Action Coding System (FACS; Ekman & Friesen, 1978a) coding of the facial productions showed that young adults succeeded in activating 18 of the 20 target actions units, although they often coactivated other action units. Voluntary control was clearly better for some action units than for others, with a pattern of differences between action units consistent with previous work in children and adolescents. Copyright 2010 APA, all rights reserved.

  10. Market Brief: Status of the Voluntary Renewable Energy Certificate Market (2011 Data)

    Energy Technology Data Exchange (ETDEWEB)

    Heeter, J.; Armstrong, P.; Bird, L.

    2012-09-01

    This report documents the status and trends of U.S. 'voluntary' markets -- those in which consumers and institutions purchase renewable energy to match their electricity needs on a voluntary basis. Voluntary REC markets continue to exhibit growth and spur renewable energy development. Voluntary green power markets provide an additional revenue stream for renewable energy projects and raise consumer awareness of the benefits of renewable energy. Although a full estimate of the size of the voluntary market is not available for 2011, this review uses indicative metrics to capture 2011 voluntary market trends.

  11. Market Brief. Status of the Voluntary Renewable Energy Certificate Market (2011 Data)

    Energy Technology Data Exchange (ETDEWEB)

    Heeter, Jenny [National Renewable Energy Lab. (NREL), Golden, CO (United States); Armstrong, Philip [National Renewable Energy Lab. (NREL), Golden, CO (United States); Bird, Lori [National Renewable Energy Lab. (NREL), Golden, CO (United States)

    2012-09-01

    This report documents the status and trends of U.S. 'voluntary' markets -- those in which consumers and institutions purchase renewable energy to match their electricity needs on a voluntary basis. Voluntary REC markets continue to exhibit growth and spur renewable energy development. Voluntary green power markets provide an additional revenue stream for renewable energy projects and raise consumer awareness of the benefits of renewable energy. Although a full estimate of the size of the voluntary market is not available for 2011, this review uses indicative metrics to capture 2011 voluntary market trends.

  12. The epididymis, cytoplasmic droplets and male fertility

    Institute of Scientific and Technical Information of China (English)

    Trevor G Cooper

    2011-01-01

    The potential of spermatozoa to become motile during post-testicular maturation,and the relationship between the cytoplasmic droplet and fertilizing capacity are reviewed.Post-testicular maturation of spermatozoa involves the autonomous induction of motility,which can occur in vivo in testes with occluded excurrent ducts and in vitro in testicular explants,and artefactual changes in morphology that appear to occur in the testis in vitro.Both modifications may reflect time-dependent oxidation of disulphide bonds of head and tail proteins.Regulatory volume decrease(RVD),which counters sperm swelling at ejaculation,is discussed in relation to loss of cytoplasmic droplets and consequences for fertility.It is postulated that:(i)fertile males possess spermatozoa with sufficient osmolytes to drive RVD at ejaculation,permitting the droplet to round up and pinch off without membrane rupture; and(ⅱ)infertile males possess spermatozoa with insufficient osmolytes so that RVD is inadequate,the droplet swells and the resulting flagellar angulation prevents droplet loss.Droplet retention at ejaculation is a harbinger of infertility caused by failure of the spermatozoon to negotiate the uterotubal junction or mucous and reach the egg.In this hypothesis,the epididymis regulates fertility indirectly by the extent of osmolyte provision to spermatozoa,which influences RVD and therefore droplet loss.Man is an exception,because ejaculated human spermatozoa retain their droplets.This may reflect their short midpiece,approximating head length,permitting a swollen droplet to extend along the entire midpiece; this not only obviates droplet migration and flagellar angulation but also hampers droplet loss.

  13. Adubarroz: a brazilian experience for fertilization and liming recommendation of irrigated rice via computational system

    Directory of Open Access Journals (Sweden)

    Felipe de Campos Carmona

    Full Text Available ABSTRACT: Recommendations for fertilizing irrigated rice in southern Brazil have been constantly evolving over years. In this process, the influence of factors such as the development cycle of varieties and sowing period increased. Thus, computational tools that take these and others important aspects into account can potentiate the fertilization response of rice. This study describes the computer program "ADUBARROZ". The software provides recommendations of fertilizer rates and liming requirements of irrigated rice, based on information entered by the user. The system takes various factors that regulate the crop response to fertilization into account. A final report is established with the graphical representation of input management over time.

  14. Costs and benefits of industrial reporting and voluntary targets for energy efficiency. A report to the Congress of the United States. Volume II: Appendices

    Energy Technology Data Exchange (ETDEWEB)

    1994-02-01

    This part sets forth the regulations for the Industrial Energy conservation Program established under Part E of Title III of the Act. It includes criteria and procedures for the identification of reporting corporations, reporting requirements, criteria and procedures for exemption from filing reports directly with DOE, voluntary industrial energy efficiency improvement targets and voluntary recovered materials utilization targets. The purpose of the program is to promote increased energy conservation by American industry and, as it relates to the use of recovered materials, to conserve valuable energy and scarce natural resources.

  15. Research Progress in the Effect and Mechanism of Fertilization Measures on Soil Fertility

    Institute of Scientific and Technical Information of China (English)

    Dongfeng; HUANG; Limin; WANG; Weihua; LI; Xiaoxuan; QIU

    2015-01-01

    This paper firstly summarized the domestic and foreign research progress in the relationship between fertilization measures and soil fertility. It elaborated the relationship between fertilization measures and basic physical and chemical properties,soil enzyme activity,soil microorganism fertility index,and soil animal fertility index. It pointed out future researches about the relationship between fertilization measures and soil fertility include:( i) the relationship between fine and high efficient input of organic fertilizer and soil fertility,( ii) in-depth research of soil zoology fertility index,( iii) soil biology about long-term fertilization,and( iv) soil fertilization and agricultural diffused pollution. It is intended to provide scientific reference for improving farmland soil fertility and maintaining excellent ecological environment of farmland through proper fertilization measures.

  16. Voluntary ingestion of buprenorphine as a refined analgesic strategy

    DEFF Research Database (Denmark)

    Jacobsen, Kirsten Rosenmaj; Kalliokoski, Otto Henrik; Hau, Jann

    2011-01-01

    Buprenorphine is a widely used analgesic for laboratory rodents. Administration of the drug in an attractive food item for voluntary ingestion is a desirable way to administer the drug noninvasively. The method refi nes the standard analgesic procedure and has the potential to improve the welfare...

  17. Value orientations, expectations and voluntary contributions in public goods

    NARCIS (Netherlands)

    Offerman, T.J.S.; Schram, A.J.H.C.; Sonnemans, J.H.

    1996-01-01

    An experimental analysis of voluntary, binary contributions for step-level public goods is presented. Independent information is obtained on individual value orientation and expectations about the behavior of other subjects using incentive compatible mechanisms. The effects of increasing payoffs for

  18. Value Orientations, Expectations and Voluntary Contributions in Public Goods

    NARCIS (Netherlands)

    Sonnemans, J.; Schram, A.; Offermans, T.

    1996-01-01

    An experimental analysis of voluntary, binary contributions for step-level public goods is presented. Independent information is obtained on individual value orientation and expectations about the behavior of other subjects using incentive compatible mechanisms. The effects of increasing payoffs for

  19. 77 FR 55487 - Agency Information Collection Activities; Voluntary Customer Survey

    Science.gov (United States)

    2012-09-10

    ... U.S. Customs and Border Protection, Department of Homeland Security, and sent via electronic mail to... SECURITY U.S. Customs and Border Protection Agency Information Collection Activities; Voluntary Customer Survey AGENCY: U.S. Customs and Border Protection, Department of Homeland Security. ACTION: 30-Day...

  20. ANALYSIS OF INTENTION TO CONTINUE SERVICES AMONG RECRUITED VOLUNTARY SOLDIERS

    Directory of Open Access Journals (Sweden)

    Kuo-Wei Lin

    2012-01-01

    Full Text Available In order to attract more promising young people to join the military and enhance combat capability, Taiwan’s Department of Defense is transforming the nation’s military service system from a draft system, which has been in effect for more than sixty years, to an all-volunteer military force system. The government hopes that the new system not only can recruit promising voluntary soldiers, but that they also continue their military service after the contract expires in order to ensure stability in recruitment sources. This study explores the intention of voluntary soldiers to continue their military service. This study’s questionnaire encompasses five dimensions: Participation motivation, organization commitment, career planning, personality traits and departure tendency. The questionnaires were issued to 350 voluntary soldiers to explore if they intend to continue their service after their contract expires, with a total of 314 effective questionnaires that were recovered and analyzed. The results find that about half of the voluntary soldiers indicate that they do not plan on staying and continuing their service after contract expiration, which will result in understaffing in the military. In order to stabilize the prescribed number of soldiers, the existing recruiting policy and military management system should be re-adjusted.

  1. Privatizing or socializing corporate responsibility: business participation in voluntary programs

    NARCIS (Netherlands)

    Fransen, L.W.; Burgoon, B.

    2014-01-01

    This article explores why companies choose some Corporate Responsibility initiatives over others. The focus is on competing voluntary programs to oversee and protect labor standards. These programs may differ with regard to two aspects: the governance of the program and the financial and managerial

  2. 77 FR 50584 - Voluntary Licensing of Amateur Rocket Operations

    Science.gov (United States)

    2012-08-22

    ... are summarized below. Total Benefits and Costs The FAA does not require licensing of amateur rocket... of this rule. To the extent the licensing requirements provide a societal benefit, those benefits... Federal Aviation Administration 14 CFR Part 400 RIN 2120-AJ84 Voluntary Licensing of Amateur...

  3. Board and auditor interlocks and voluntary disclosure in annual reports

    NARCIS (Netherlands)

    Braam, G.J.M.; Borghans, L.

    2014-01-01

    Purpose – The purpose of this study is to explore whether interlock ties between the board of directors and the external auditors facilitate the cross-firm diffusion of voluntary disclosures in annual reports. Design/methodology/approach – Using a sample of 149 non-financial companies publicly lis

  4. Refreshing the "Voluntary National Content Standards in Economics"

    Science.gov (United States)

    MacDonald, Richard A.; Siegfried, John J.

    2012-01-01

    The second edition of the "Voluntary National Content Standards in Economics" was published by the Council for Economic Education in 2010. The authors examine the process for revising these precollege content standards and highlight several changes that appear in the new document. They also review the impact the standards have had on precollege…

  5. Human Economy and Entrepreneurial Learning in a Voluntary Organization

    DEFF Research Database (Denmark)

    Revsbech, Christine

    2014-01-01

    "Based on five months anthropological field study in a British affiliate of an American charity in London, Revsbech asks what does learning look like in a social voluntary organization for youth. Her chapter argues that volunteers develop entrepreneurial abilities by shifting flexibly between...

  6. Voluntary imitation in Alzheimer’s disease patients

    Directory of Open Access Journals (Sweden)

    Ambra eBisio

    2016-03-01

    Full Text Available Although Alzheimer's disease (AD primarily manifests as cognitive deficits, the implicit sensorimotor processes that underlie social interactions, such as automatic imitation, seem to be preserved in mild and moderate stages of the disease, as is the ability to communicate with other persons. Nevertheless, when AD patients face more challenging tasks, which do not rely on automatic processes but on explicit voluntary mechanisms and require the patient to pay attention to external events, the cognitive deficits resulting from the disease might negatively affect patients’ behaviour. The aim of the present study was to investigate whether voluntary motor imitation, i.e. a volitional mechanism that involves observing another person’s action and translating this perception into one’s own action, was affected in patients with Alzheimer’s disease. Further, we tested whether this ability was modulated by the nature of the observed stimulus by comparing the ability to reproduce the kinematic features of a human demonstrator with that of a computerized-stimulus. AD patients showed an intact ability to reproduce the velocity of the observed movements, particularly when the stimulus was a human agent. This result suggests that high-level cognitive processes involved in voluntary imitation might be preserved in mild and moderate stages of AD and that voluntary imitation abilities might benefit from the implicit interpersonal communication established between the patient and the human demonstrator.

  7. 77 FR 53963 - Voluntary Intermodal Sealift Agreement (VISA)

    Science.gov (United States)

    2012-09-04

    ... amended to note that each voluntary agreement expires five (5) years after the date it becomes effective... Concept The mission of VISA is to provide commercial sealift and intermodal shipping services and systems... commitments or volunteered capacity are insufficient to meet contingency requirements, and adequate shipping...

  8. Voluntary Genital Ablations: Contrasting the Cutters and Their Clients

    Directory of Open Access Journals (Sweden)

    Robyn A. Jackowich, BA

    2014-08-01

    Conclusions: This study may help identify individuals who are at risk of performing illegal castrations. That information may help healthcare providers protect individuals with extreme castration ideations from injuring themselves or others. Jackowich RA, Vale R, Vale K, Wassersug RJ, and Johnson TW. Voluntary genital ablations: Contrasting the cutters and their clients. Sex Med 2014;2:121–132.

  9. Force-directed design of a voluntary closing hand prosthesis

    NARCIS (Netherlands)

    De Visser, H.; Herder, J.L.

    2000-01-01

    This paper presents the design of a body-powered voluntary closing prosthetic hand. It is argued that the movement of the fingers before establishing a grip is much less relevant for good control of the object held than the distribution of forces once the object has been contacted. Based on this not

  10. Mobilising voluntary contributions in public urban regeneration – a review

    DEFF Research Database (Denmark)

    Larsen, Jacob Norvig; Jensen, Jesper Ole; Agger, Annika

    Research on volunteerism indicates that one third of all adults in Denmark regularly contribute with voluntary labour in social relief work, community-based organizations, non-governmental organizations, or otherwise. In this paper we ask if and how urban regeneration might benefit from the appar...... of voluntary labour and voluntary associations in publicly subsidised urban regeneration. Empirical data will be collected through in-depth case studies in selected communities in both metropolitan neighbourhoods and smaller market towns....... to community development, urban policy, etc. In addition to this, the paper presents results from a survey exploring the extent and character of volunteerism in a number of integrated urban regeneration projects. The paper proposes a systematic overview of experiences with voluntary inputs and engagement...... in relation to public policy arenas and activities, particularly within urban policy and the community development fields. A categorization is proposed as regards different ways and models of civic engagement and major challenges are outlined. The paper is first step of a research project exploring potential...

  11. From participation to consumption? : Consumerism in voluntary sport clubs

    NARCIS (Netherlands)

    van der Roest, J.

    2015-01-01

    In recent years dark clouds seem to have gathered over the institution of the voluntary sport club. General societal developments such as individualisation and commercialisation have given rise to concerns regarding the transfer of such attitudes to sport clubs. Many people who are involved in and a

  12. The Limitations of Voluntary Repatriation and Resettlement of Refugees

    NARCIS (Netherlands)

    Zieck, M.; Chetail, V.; Bauloz, C.

    2014-01-01

    UNHCR is charged with the pursuit of durable solutions for the problem of refugees. Those solutions are voluntary repatriation and assimilation within new national communities which means either local integration in the country of refuge - tangentially touched upon in this paper - or resettlement in

  13. Study of the Voluntary Public School Choice Program. Final Report

    Science.gov (United States)

    Yin, Robert K.; Ahonen, Pirkko S.

    2008-01-01

    The Voluntary Public School Choice (VPSC) Program supports the emergence and growth of choice initiatives across the country, by assisting states and local school districts in developing innovative strategies to expand public school choice options for students. This report contains the final assessment of the first five years of the VPSC Program…

  14. Study of the Voluntary Public School Choice Program. Interim Report

    Science.gov (United States)

    Yin, Robert K.; Ahonen, Pirkko; Kim, Dawn

    2007-01-01

    The purpose of the Voluntary Public School Choice (VPSC) Program is to assist states and local school districts in the development of innovative strategies to expand options for students, and to encourage transfers of students from low-performing to higher-performing schools. This report presents interim findings from the National Evaluation of…

  15. Privatizing or socializing corporate responsibility: business participation in voluntary programs

    NARCIS (Netherlands)

    L.W. Fransen; B. Burgoon

    2013-01-01

    This article explores why companies choose some Corporate Responsibility initiatives over others. The focus is on competing voluntary programs to oversee and protect labor standards. These programs may differ with regard to two aspects: the governance of the program and the financial and managerial

  16. What roles are there for government in voluntary environmental programs?

    NARCIS (Netherlands)

    van der Heijden, J.

    2015-01-01

    This article seeks to understand to a greater extent why and how governments are involved in voluntary environmental programmes (VEPs). A better understanding of the role(s) of government in VEPs is of relevance because the current VEP literature considers such involvement one of the key conditions

  17. A cardiorespiratory classifier of voluntary and involuntary electrodermal activity

    Directory of Open Access Journals (Sweden)

    Sejdic Ervin

    2010-02-01

    Full Text Available Abstract Background Electrodermal reactions (EDRs can be attributed to many origins, including spontaneous fluctuations of electrodermal activity (EDA and stimuli such as deep inspirations, voluntary mental activity and startling events. In fields that use EDA as a measure of psychophysiological state, the fact that EDRs may be elicited from many different stimuli is often ignored. This study attempts to classify observed EDRs as voluntary (i.e., generated from intentional respiratory or mental activity or involuntary (i.e., generated from startling events or spontaneous electrodermal fluctuations. Methods Eight able-bodied participants were subjected to conditions that would cause a change in EDA: music imagery, startling noises, and deep inspirations. A user-centered cardiorespiratory classifier consisting of 1 an EDR detector, 2 a respiratory filter and 3 a cardiorespiratory filter was developed to automatically detect a participant's EDRs and to classify the origin of their stimulation as voluntary or involuntary. Results Detected EDRs were classified with a positive predictive value of 78%, a negative predictive value of 81% and an overall accuracy of 78%. Without the classifier, EDRs could only be correctly attributed as voluntary or involuntary with an accuracy of 50%. Conclusions The proposed classifier may enable investigators to form more accurate interpretations of electrodermal activity as a measure of an individual's psychophysiological state.

  18. The decision making control instrument to assess voluntary consent.

    Science.gov (United States)

    Miller, Victoria A; Ittenbach, Richard F; Harris, Diana; Reynolds, William W; Beauchamp, Tom L; Luce, Mary Frances; Nelson, Robert M

    2011-01-01

    The decision to participate in a research intervention or to undergo medical treatment should be both informed and voluntary. The aim of the present study was to develop an instrument to measure the perceived voluntariness of parents making decisions for their seriously ill children. A total of 219 parents completed questionnaires within 10 days of making such a decision at a large, urban tertiary care hospital for children. Parents were presented with an experimental form of the Decision Making Control Instrument (DMCI), a measure of the perception of voluntariness. Data obtained from the 28-item form were analyzed using a combination of both exploratory and confirmatory factor analytic techniques. The 28 items were reduced to 9 items representing 3 oblique dimensions: Self-Control, Absence of Control, and Others' Control. The hypothesis that the 3-factor covariance structure of our model was consistent with that of the data was supported. Internal consistency for the scale as a whole was high (0.83); internal consistency for the subscales ranged from 0.68 to 0.87. DMCI scores were associated with measures of affect, trust, and decision self-efficacy, supporting the construct validity of the new instrument. The DMCI is an important new tool that can be used to inform our understanding of the voluntariness of treatment and research decisions in medical settings.

  19. 77 FR 67269 - Voluntary Licensing of Amateur Rocket Operations; Withdrawal

    Science.gov (United States)

    2012-11-09

    ... it received. DATES: The direct final rule published on August 22, 2012, at 77 FR 50584 is withdrawn... withdraws Amendment No. 400-4 published at 77 FR 50584 on August 22, 2012. Issued in Washington, DC, on... Federal Aviation Administration 14 CFR Part 400 RIN 2120-AK16 Voluntary Licensing of Amateur...

  20. Environmental Concern and Involvement of Individuals in Selected Voluntary Associations

    Science.gov (United States)

    Schuett, Michael A.; Ostergren, David.

    2003-01-01

    The authors examined environmental concern and involvement of individuals in two voluntary associations, the International Mountain Bicycling Association (IMBA) and National Off-Highway Vehicle Conservation Council, Inc. (NOHVCC). Environmental concerns were assessed using the New Environmental Paradigm (NEP). When compared, results from 10 of 12…

  1. 28 CFR 549.41 - Voluntary admission and psychotropic medication.

    Science.gov (United States)

    2010-07-01

    ... medication. 549.41 Section 549.41 Judicial Administration BUREAU OF PRISONS, DEPARTMENT OF JUSTICE INSTITUTIONAL MANAGEMENT MEDICAL SERVICES Administrative Safeguards for Psychiatric Treatment and Medication § 549.41 Voluntary admission and psychotropic medication. (a) A sentenced inmate may be...

  2. Mobilising voluntary contributions in public urban regeneration – a review

    DEFF Research Database (Denmark)

    Agger, Annika; Jensen, Jesper Ole; Larsen, Jacob Norvig

    Research on volunteerism indicates that one third of all adults in Denmark regularly contribute with voluntary labour in social relief work, community-based organizations, non-governmental organizations, or otherwise. In this paper we ask if and how urban regeneration might benefit from the appar...

  3. Selection and inhibition mechanisms for human voluntary action decisions.

    Science.gov (United States)

    Zhang, Jiaxiang; Hughes, Laura E; Rowe, James B

    2012-10-15

    One can choose between action alternatives that have no apparent difference in their outcomes. Such voluntary action decisions are associated with widespread frontal-parietal activation, and a tendency to inhibit the repetition of a previous action. However, the mechanism of initiating voluntary actions and the functions of different brain regions during this process remains largely unknown. Here, we combine computational modeling and functional magnetic resonance imaging to test the selection and inhibition mechanisms that mediate trial-to-trial voluntary action decisions. We fitted an optimized accumulator model to behavioral responses in a finger-tapping task in which participants were instructed to make chosen actions or specified actions. Model parameters derived from each individual were then applied to estimate the expected accumulated metabolic activity (EAA) engaged in every single trial. The EAA was associated with blood oxygenation level-dependent responses in a decision work that was maximal in the supplementary motor area and the caudal anterior cingulate cortex, consistent with a competitive accumulation-to-threshold mechanism for action decision by these regions. Furthermore, specific inhibition of the previous action's accumulator was related to the suppression of response repetition. This action-specific inhibition correlated with the activity of the right inferior frontal gyrus, when the option to repeat existed. Our findings suggest that human voluntary action decisions are mediated by complementary processes of intentional selection and inhibition.

  4. Validating the Psychological Climate Scale in Voluntary Child Welfare

    Science.gov (United States)

    Zeitlin, Wendy; Claiborne, Nancy; Lawrence, Catherine K.; Auerbach, Charles

    2016-01-01

    Objective: Organizational climate has emerged as an important factor in understanding and addressing the complexities of providing services in child welfare. This research examines the psychometric properties of each of the dimensions of Parker and colleagues' Psychological Climate Survey in a sample of voluntary child welfare workers. Methods:…

  5. Voluntary activation of trapezius measured with twitch interpolation

    DEFF Research Database (Denmark)

    Taylor, Janet L; Olsen, Henrik Baare; Sjøgaard, Gisela

    2009-01-01

    This study investigated the feasibility of measuring voluntary activation of the trapezius muscle with twitch interpolation. Subjects (n=8) lifted the right shoulder or both shoulders against fixed force transducers. Stimulation of the accessory nerve in the neck was used to evoke maximal twitche...

  6. [Prolactin and male fertility].

    Science.gov (United States)

    Schreiber, G; Börner, A; Lauterbach, H; Thiel, W

    1983-03-01

    On 68 selected patients with disturbances of the potentia generandi et/sive coeundi (25 males with healthy metabolism and 43 males with diabetes) as well as 14 control persons PRL, LH, FSH, testosterone and oestradiol were determined radioimmunologically and the results were ascribed to sexological, clinical, spermatological and testo-histological findings. A statistically secure correlation was found between PRL values and disturbance of the libido as well as the presence of a gynaecomasty. PRL did not correlate with the spermatological variables volume of ejaculate, relative and absolute number of spermatozoa and motility. PRL did also not correlate with the testohistological findings. A relation between PRL and the peptide hormones LH and FSH as well as the steroid hormones testosterone and oestradiol could not be ascertained. Therefore the diagnostic values of a PRL determination is much limited; the pertinency of a hyperprolactinaemia may be increased by the proof of the symptoms reduction of libido and gynaecomasty with simultaneous disturbance of fertility. In our opinion the definition of hyperprolactinaemia needs revision, since at only determination of the basal value of more than 800 mU/l no more frequently pathologically andrological findings are to be observed than below 200 mU/l.

  7. Fertilization of SRC willow. II

    DEFF Research Database (Denmark)

    Sevel, L; Ingerslev, Morten; Nord-Larsen, Thomas

    2014-01-01

    Short rotation coppice (SRC) willow is an emerging cropping system in focus for production of biomass for energy. To increase production, the willow is commonly fertilized, but studies have shown differing effects of fertilization on biomass production, ranging from almost no response...... impacts of different doses of mineral fertilizer, manure and sewage sludge in a commercially grown SRC willow stand. We examined macro nutrient and heavy metal leaching rates and calculated element balances to evaluate the environmental impact. Growth responses were reported in a former paper (Sevel et al....... “Fertilization of SRC Willow, I: Biomass Production Response” Bioenergy Research, 2013). Nitrogen leaching was generally low, between 1 and 7 kg N ha−1 year−1 when doses of up to 120 kg N ha−1 year−1 were applied. Higher doses of 240 and 360 kg N ha−1 as single applications caused leaching of 66 and 99 kg N ha−1...

  8. Fertility Desire and Reproductive Health

    African Journals Online (AJOL)

    Understanding fertility desire and reproductive health care needs of HIV positive men and women in the era ... and related consequences. ... inform national policy decisions on PMTCT, HIV ... The study population was included proportional to.

  9. Food security: Fertilizing hidden hunger

    Science.gov (United States)

    Müller, Christoph; Elliott, Joshua; Levermann, Anders

    2014-07-01

    Atmospheric CO2 fertilization may go some way to compensating the negative impact of climatic changes on crop yields, but it comes at the expense of a deterioration of the current nutritional value of food.

  10. IVF-In Vitro Fertilization.

    Science.gov (United States)

    Kieffer, George H.

    1980-01-01

    Issues surrounding the controversial topic of in vitro fertilization and artificial manipulation of reproduction are discussed. The author examines the moral and ethical implications and presents results of a survey of various religious groups. (SA)

  11. The Fertility Transition in Bavaria

    OpenAIRE

    Brown, John C.; Timothy W. Guinnane

    2001-01-01

    The decline of human fertility that occurred in Europe and North America in the nineteenth century, and elsewhere in the twentieth century, remains a topic of debate largely because there is no accepted explanation for the event. Disagreement persists in part because researchers have rarely used the detailed quantitative information necessary to form adequate tests of alternative theories. This paper uses district-level data from Bavaria to study the correlates of the decline of fertility in ...

  12. Children Procedures and Treatment (Fertility Issues)

    Science.gov (United States)

    ... approach the subject of fertility preservation with their cancer-stricken child? How is the Oncofertility Consortium addressing the fertility preservation needs of children? How do cancer and cancer treatment affect a child's fertility? Why should fertility preservation be a priority ...

  13. Voluntary Exercise Preconditioning Activates Multiple Antiapoptotic Mechanisms and Improves Neurological Recovery after Experimental Traumatic Brain Injury.

    Science.gov (United States)

    Zhao, Zaorui; Sabirzhanov, Boris; Wu, Junfang; Faden, Alan I; Stoica, Bogdan A

    2015-09-01

    Physical activity can attenuate neuronal loss, reduce neuroinflammation, and facilitate recovery after brain injury. However, little is known about the mechanisms of exercise-induced neuroprotection after traumatic brain injury (TBI) or its modulation of post-traumatic neuronal cell death. Voluntary exercise, using a running wheel, was conducted for 4 weeks immediately preceding (preconditioning) moderate-level controlled cortical impact (CCI), a well-established experimental TBI model in mice. Compared to nonexercised controls, exercise preconditioning (pre-exercise) improved recovery of sensorimotor performance in the beam walk task, as well as cognitive/affective functions in the Morris water maze, novel object recognition, and tail-suspension tests. Further, pre-exercise reduced lesion size, attenuated neuronal loss in the hippocampus, cortex, and thalamus, and decreased microglial activation in the cortex. In addition, exercise preconditioning activated the brain-derived neurotrophic factor pathway before trauma and amplified the injury-dependent increase in heat shock protein 70 expression, thus attenuating key apoptotic pathways. The latter include reduction in CCI-induced up-regulation of proapoptotic B-cell lymphoma 2 (Bcl-2)-homology 3-only Bcl-2 family molecules (Bid, Puma), decreased mitochondria permeabilization with attenuated release of cytochrome c and apoptosis-inducing factor (AIF), reduced AIF translocation to the nucleus, and attenuated caspase activation. Given these neuroprotective actions, voluntary physical exercise may serve to limit the consequences of TBI.

  14. Voluntary immunomodulation: potentiality and implications for long-duration manned space-flights

    Science.gov (United States)

    Geuna, Stefano

    The influence of psychological and neural factors on immunologic activity has been dedicated a growing interest over the past fifteen years, since the publication ofPsychoneuroimmunology by Robert Ader in 1981. Studies on this topic gave evidence for bi-directional communication between psychosocial, behavioural, neuroanatomical and neuroendocrine processes with the immune system and the detrimental effects of various stressors, physical and psychological, on immune reactions were widely investigated with reports of stress-induced changes in immune paramenters and immunocompetence. Much of the evidence support the notion that stress is associated with an increase in those diseases against which the immune system defends. Recently, several studies showed that immune functions can be influenced voluntarily and the term voluntary immunomodulation was coined to describe the use of various hypnosis-like and relaxation/imagery techniques for the self-regulation of immune activity. Alterations in the immune regulatory system are one of the most critical issues to be addressed in relation to crew health management during space missions, especially long-term ones. Providing crewmembers with a tool to enhance immunocompetence might be of great value to defend against some severe diseases, such as cancer and infectious illness, which may be elicited in outer space. In this view, a critical assessment of the potential usefulness of voluntary immunomodulation for crew health maintenance during manned space-flight is presented and discussed.

  15. Determinants of voluntary change of the external audit firm in brazilian market

    Directory of Open Access Journals (Sweden)

    Felipe Roberto Rocha Junior

    2016-09-01

    Full Text Available This paper aims to study the factors that influence the decision of voluntary change of the audit firm. In Brazil there is a requirement of compulsory replacement (audit rotation for at least every 5 years and at intervals of 3 years for their rehiring. However, during the period of adoption of international accounting standards, the brazilian securities regulator – CVM, has suspended the requirement, what turns the period of 2010 to 2014 interesting to this research. Previous studies relate the auditor's change decision with auditor characteristics and their relationship with the client; firm characteristics and changes in the top management; and corporate governance mechanisms. This paper aims to investigate if these and other variables explain its phenomenon in the brazilian market, characterized by the concentration of control and low protection of minority investor. The results suggest that a modified audit report, the company’s growth and being listed in Novo Mercado or Nível 2, segments of more demanding requirements of coroporate governance of BM&FBovespa, increase the likelihood of replacement of auditors; while hiring non-audit services reduces the probability of voluntary change.

  16. 7 CFR 4290.585 - Voluntary decrease in RBIC's Regulatory Capital.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 15 2010-01-01 2010-01-01 false Voluntary decrease in RBIC's Regulatory Capital. 4290... INVESTMENT COMPANY (âRBICâ) PROGRAM Managing the Operations of a RBIC Voluntary Decrease in Regulatory Capital § 4290.585 Voluntary decrease in RBIC's Regulatory Capital. You must obtain the Secretary's prior...

  17. 13 CFR 107.585 - Voluntary decrease in Licensee's Regulatory Capital.

    Science.gov (United States)

    2010-01-01

    ... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false Voluntary decrease in Licensee's... SMALL BUSINESS INVESTMENT COMPANIES Managing the Operations of a Licensee Voluntary Decrease in Licensee's Regulatory Capital § 107.585 Voluntary decrease in Licensee's Regulatory Capital. You must obtain...

  18. Status and Trends in the U.S. Voluntary Green Power Market (2012 Data)

    Energy Technology Data Exchange (ETDEWEB)

    Heeter, J.; Nicholas, T.

    2013-10-01

    Voluntary green power markets are those in which consumers and institutions voluntarily purchase renewable energy to match their electricity needs. Voluntary action provides a revenue stream for renewable energy projects and raises consumer awareness of the benefits of renewable energy. These markets continued to exhibit growth and stimulate renewable energy development in 2012. This paper reviews the voluntary market and identifies market trends.

  19. 78 FR 70915 - Notice of December 11 Advisory Committee on Voluntary Foreign Aid Meeting

    Science.gov (United States)

    2013-11-27

    ...; ] AGENCY FOR INTERNATIONAL DEVELOPMENT Notice of December 11 Advisory Committee on Voluntary Foreign Aid... Committee on Voluntary Foreign Aid (ACVFA). Date: Wednesday, December 11, 2013. Time: 2:30 p.m. to 4:00 p.m... on Voluntary Foreign Aid (ACVFA), U.S. Agency for International Development. BILLING CODE 6116-01-P...

  20. 78 FR 30267 - Notice of June 12 Advisory Committee on Voluntary Foreign Aid Meeting

    Science.gov (United States)

    2013-05-22

    ... DEVELOPMENT Notice of June 12 Advisory Committee on Voluntary Foreign Aid Meeting AGENCY: United States Agency... Committee Act, notice is hereby given of a meeting of the Advisory Committee on Voluntary Foreign Aid (ACVFA... Voluntary Foreign Aid (ACVFA), U.S. Agency for International Development. BILLING CODE P...

  1. 78 FR 3878 - Renewal of the Advisory Committee on Voluntary Foreign Aid

    Science.gov (United States)

    2013-01-17

    ...; ] AGENCY FOR INTERNATIONAL DEVELOPMENT Renewal of the Advisory Committee on Voluntary Foreign Aid AGENCY... renewal of the Advisory Committee on Voluntary Foreign Aid for a two-year period beginning January 10... Voluntary Foreign Aid (ACVFA), U.S. Agency for International Development. BILLING CODE P...

  2. 75 FR 81205 - Renewal of the Advisory Committee on Voluntary Foreign Aid

    Science.gov (United States)

    2010-12-27

    ... DEVELOPMENT Renewal of the Advisory Committee on Voluntary Foreign Aid AGENCY: United States Agency for... Voluntary Foreign Aid for a two-year period beginning January 15, 2011 is necessary and in the public... Hubbard, Executive Director, Advisory Committee on Voluntary Foreign Aid (ACVFA), U.S. Agency...

  3. Reflections on fertility dynamics in Romania.

    Science.gov (United States)

    Bratu, Eugenia Claudia; Minca, Dana Galieta

    2012-01-01

    Aims to highlight the changes occurred in the evolution of the fertility phenomenon in Romania, focusing on developments in the general fertility rate, total fertility rate, number of live births, and on the construction of specific indicators to reveal the source of demographic change. Several theories on the factors that may cause fertility decline it were outlined, underlining the presence of these factors during fertility dynamics in our country. After 1990, population decline may be explained by a close inter-relationship between economic theories (worsening economic conditions lead to decreased fertility) and the second demographic transition (postponement of births, fertility change model).

  4. Regulating effect of fertilization form on gas exchange in leaves of sweet potato under different soil water conditions%不同土壤水分条件下施肥方式对甘薯叶片气体交换的调节作用

    Institute of Scientific and Technical Information of China (English)

    许育彬; 陈越; 齐向英

    2009-01-01

    采用盆栽试验,以甘薯品种秦薯4号和619为材料,研究了不同土壤水分条件下施肥方式对甘薯叶片气体交换的影响.结果表明,土壤水分和施肥方式对甘薯叶片净光合速率(Pn)、蒸腾速率(Tr)、水分利用效率(WUE)、气孔导度(Gs)、胞间CO2浓度(Ci)以及气孔限制值(Ls)有显著或极显著的影响,水肥之间存在明显的互作效应.与土壤湿润( 田间持水量70%~75%)相比,土壤轻旱(田间持水量40%~45%)对甘薯叶片Pn、Tr、WUE 、Gs、Ci以及Ls的影响较小,而重旱(田间持水量30%~35%)下,Pn、Tr、WUE、Gs和Gs 大幅下降,Ci明显上升.施肥有助于促进提高Pn、Tr、Gs以及Ls,降低Ci,而且氮磷配施的效果优于氮肥单施.Ci和Ls 的变化说明在土壤轻旱(40%~45%)条件下,甘薯叶片气体交换主要受气孔因素限制,而重旱(30%~35%)主要受非气孔因素限制.施肥通过改善气孔因素对甘薯叶片气体交换产生促进效应.%To understand the regulating effects of soil water and fertilization on gas exchange in sweet potato leaves under different condit ions of soil water, with two cultivars of Qinshu 4 and 619 as materials, a pot e xperiment was conducted to measure and assay photosynthesis rate(Pn), water use efficiency(WUE), transpiration rate(Tr), stomatal conductance(Gs ), intercellular CO2 concentration(Ci) and stomatal limitation value(L s). The results showed that soil water and fertilization significantly influen ce Pn, Tr, WUE, Gs and Ls. An apparent interaction existed between soil water and fertilization. Compared to the soil water content of 70%~75%,the cha nges of Pn, Tr, WUE, Gs and Ls were smaller under the soil water of 40% ~45%, while under the soil water of 30%~35%, Pn, Tr, WUE, Gs and Ls, decreased significantly but Ci increased remarkably. Fertilization could enh ance Pn, Tr, WUE, Gs and Ls, but reduce Ci. The regulating effect of these indexes with combined application of nitrogen and

  5. (IN) FERTILITY AND THE MODERN FEMALE LIFE COURSE IN TWO SOUTHERN NIGERIAN COMMUNITIES

    Science.gov (United States)

    Hollos, Marida; Whitehouse, Bruce

    2013-01-01

    Being “modern” is an aspiration for many in sub-Saharan Africa and entails certain widely held expectations regarding material living conditions and social status. Using ethnographic and survey data on female fertility from two communities of southern Nigeria, this article describes some of the ways women are becoming modern and analyzes the forces behind these changes. The discussion includes education, initiation rites, premarital pregnancy, marriage, and the influence of Pentecostal Christianity. In agreement with modernization theory, there is a trend toward women becoming more educated and autonomous. They also increasingly valorize monogamy, companionate marriage, smaller families, and inclusion in the formal economy. In contradiction to the expectations of modernization theory, there is no decline in supernatural beliefs. Contemporary Christian churches are important to women becoming modern by helping them develop networks through voluntary associations, responding to women’s aspirations for material goods, alleviating kin obligations, and encouraging personal spiritual advancement. (Southern Nigeria women, fertility, modernity, Pentecostal Christianity) PMID:23894209

  6. Greenhouse evaluation and environmental impact assessment of different urine-derived struvite fertilizers as phosphorus sources for plants.

    Science.gov (United States)

    Antonini, Samantha; Arias, Maria Alejandra; Eichert, Thomas; Clemens, Joachim

    2012-11-01

    A selection of six urine-derived struvite fertilizers generated by innovative precipitation technologies was assessed for their quality and their effectiveness as phosphorus sources for crops. Struvite purity was influenced by drying techniques and magnesium dosage. In a greenhouse experiment, the urine fertilizers led to biomass yields and phosphorus uptakes comparable to or higher than those induced by a commercial mineral fertilizer. Heavy metal concentrations of the different struvite fertilizers were below the threshold limits specified by the German Fertilizer and Sewage Sludge Regulations. The computed loading rates of heavy metals to agricultural land were also below the threshold limits decreed by the Federal Soil Protection Act. Urine-derived struvite contributed less to heavy metal inputs to farmland than other recycling products or commercial mineral and organic fertilizers. When combined with other soil conditioners, urine-derived struvite is an efficient fertilizer which covers the magnesium and more than half of the phosphorus demand of crops.

  7. Perspectives on access to in vitro fertilization in Portugal

    Directory of Open Access Journals (Sweden)

    S. Silva

    2012-04-01

    Full Text Available OBJECTIVE: To analyze users' reasons for choosing in vitro fertilization treatment in public or private services and to identify their suggestions for improving fertility treatment. METHODS: A qualitative study using an interpretative approach was conducted. Fifteen semi-structured interviews were conducted with patients undergoing in vitro fertilization treatment (nine women, one man and five couples at home or at their workplace in the districts of Viana do Castelo, Braga, Porto and Lisbon, Portugal, between July 2005 and February 2006. RESULTS: Users evaluated access to in vitro fertilization treatment in public and private services based mainly on their individual experiences and called for more access to less costly, faster and friendlier care with suitable facilities, appropriate time management and caring medical providers. These perceptions were also associated with views on the need for fighting stigmatization of infertility, protecting children's rights and guaranteeing sustainability of health care system. Interviewees sought to balance reduced waiting time and more attentive care with costs involved. The choice of services depended on the users' purchase power and place of residence and availability of attentive care. CONCLUSIONS: Current national policies on in vitro fertilization treatment meet user's demands of promoting access to, and quality, availability and affordability of in vitro fertilization treatment. However, their focus on legal regulation and technical-scientific aspects contrasts with the users' emphasis on reimbursement, insurance coverage and focus on emotional aspects of the treatment. The study showed these policies should ensure insurance coverage, participation of user representatives in the National Council for Assisted Reproductive Technology, promotion of infertility research and certification of fertility laboratories.

  8. Patriarchy and fertility in Albania

    Directory of Open Access Journals (Sweden)

    Mathias Lerch

    2013-07-01

    Full Text Available BACKGROUND Theories of fertility collapse in the post-socialist era imply a decline in the moral primacy of traditional social institutions. Yet gender inequality actually increased in many countries, and there is a scarcity of empirical evidence for the role played by traditional social institutions in reproductive decision-making. OBJECTIVE We investigate whether patriarchal institutions sustained the fertility levels in Albania. The geography of marriage and family enlargement is related to the importance of patriarchy in kinship organisation and in the public sphere. To account for this spatial relationship we test the evidence for different pathways in patriarchal influence on reproductive decision-making including social effects, socialisation in patriarchal ideals, and the promotion of male fertility. METHODS We reconstruct reproductive histories from the 2001 Census and use data on attitudes and fertility intentions from the Reproductive and Health Survey 2002. Multilevel logistic regressions on marriage and (the intention of higher order births are used. RESULTS A majority of women endorsed patriarchal ideals and fertility transition was less advanced in more patriarchal municipalities. Patriarchal kinship organisation promoted early marriages and high fertility, which is shown to be achieved by social learning among peers and intergenerational social influences respectively, as well as by women's socialisation and a stopping behaviour in childbearing dominated by son-preference. Although gender inequality in the public sphere has also sustained the level of fertility and decreased the risk of marriage, it was not accounted for by these pathways of patriarchal influence. CONCLUSIONS Despite Albania's gradual opening to the world in a period of economic and political crisis, traditional social institutions remain important for family behaviours.

  9. Produtividade e qualidade tecnológica da soqueira de cana-de-açúcar submetida à aplicação de biorregulador e fertilizantes líquidos Productivity and technological quality of sugarcane ratoon subject to the application of plant growth regulator and liquid fertilizers

    Directory of Open Access Journals (Sweden)

    Marcelo de Almeida Silva

    2010-04-01

    Full Text Available O presente trabalho objetivou avaliar a aplicação de biorreguladores, associados ou não a fertilizantes líquidos, na rebrota e na produtividade da soqueira de cinco genótipos de cana-de-açúcar. O experimento foi desenvolvido no Município de Jaú, São Paulo (SP, num Latossolo Vermelho Eutroférrico. Utilizou-se o delineamento em blocos inteiramente casualizados, em esquema fatorial 5x5, constituído por cinco genótipos (IAC87-3396, IAC91-2218, IAC91-4216, IAC91-5155 e IACSP93-6006 e cinco tratamentos com biorreguladores, associados ou não a fertilizantes líquidos (Stimulate® a 0,5L ha-1; Stimulate® a 0,5L ha-1 + Starter N® a 3,0L ha-1; Stimulate® a 0,5L ha-1 + Starter N® a 3,0L ha-1 + Cellerate® a 0,5L ha-1; Etefon a 3,0L ha-1 e Testemunha, com quatro repetições. A aplicação dos produtos ocorreu 70 dias após a quarta colheita. Foram avaliados: perfilhamento, produtividade de colmos industrializáveis e de açúcar, fibra, pol % cana e açúcar total recuperável. O etefon proporcionou melhor perfilhamento, mas a resposta foi dependente do genótipo. O maior número de perfilhos promovido pelo etefon não refletiu em maior produtividade. A aplicação de Stimulate® e fertilizantes líquidos não proporcionou efeitos na qualidade da cana-de-açúcar. Houve aumento da produtividade de colmos e de açúcar, independente do genótipo, com o emprego do biorregulador Stimulate®, com ou sem complementação de fertilizante líquido, indicando a possibilidade do aumento da longevidade da cana-de-açúcar.The present work aimed to evaluate the application of plant growth regulators, associate or not to liquid fertilizers, on the ratoon sprouting and productivity of sugarcane genotypes. The experiment was carried out near Jaú city (SP, in a Eutroferric Red Latosol. The experimental design was in randomized complete blocks with factorial treatment structure 5x5, constituted by five genotypes (IAC87-3396, IAC91-2218, IAC91-4216, IAC

  10. Status and Trends in the U.S. Voluntary Green Power Market (2015 Data)

    Energy Technology Data Exchange (ETDEWEB)

    O' Shaughnessy, Eric [National Renewable Energy Lab. (NREL), Golden, CO (United States); Liu, Chang [National Renewable Energy Lab. (NREL), Golden, CO (United States); Heeter, Jenny [National Renewable Energy Lab. (NREL), Golden, CO (United States)

    2016-10-01

    The voluntary green power market refers to the sale and procurement of renewable energy for voluntary purposes by residential and commercial customers. This report reviews seven green power procurement mechanisms: utility green pricing programs, utility green tariffs, voluntary unbundled renewable energy certificates, competitive supplier green power, community choice aggregations, voluntary power purchase agreements (PPAs), and community solar. This report details the status of trends of those seven green power procurement mechanisms in 2015. Three trends -- significant growth of the voluntary PPA project pipeline, innovative green power mechanisms developed by utilities, and geographic expansion of green power mechanisms -- suggest that the green power market is likely to continue to grow in coming years.

  11. The economics of fertility.

    Science.gov (United States)

    Loraine, J A

    1982-01-01

    The statement that economics and fertility are closely interrelated is a truism. The classical economists--Adam Smith, Thomas Malthus, Karl Marx, John Stuart Mill and John Maynard Keynes appreciated this fact, and their reviews are recounted and their prescience is assessed. Adam Smith (1723-1790) was primarily concerned with the desire of humankind to better his/her material conditions. Although he did not put forward a specific population policy, the tenet of his writing is pronatalist. Economic advantages would accrue to parents by the production of many children. Yet, underneath Smith's optimism, there was an apocalyptic vision of the distant future, i.e., the "steady state" when resources would be depleted or near exhaustion, when capital accumulation would have ceased, and living standards would be dropping vertiginously. In his 1st "Essay on Population" Malthus maintained that "the power of population is infinitely greater than the power of the earth to produce subsistence of men." Malthus can be complimented on his prescience. There is little question that the planet of today is grossly overpopulated and that a great gulf exists between numbers of people and their aspirations and the resources which the earth can provide for them. Malthus was particularly concerned about the population food dilemma, and that is still much in evidence in 1982. 2 concomitants of overpopulation--excessive urbanization and joblessness--could not be foreseen by Malthus. Marx did not deny the basic tenet promulgated by Malthus but to him this was simply an artifact of capitalist society which required "enormous reserves of proletarians" in order to maintain its odius system. Officially Communist governments remain in a Marxist straitjacket regarding the population issue. Mills approach was strongly antinatalist; he saw little need for an increase in human numbers. Mills was concerned that because of unlimited population growth and wealth the earth would lose much of its

  12. Stability of equilibrium in upright stance and voluntary motion control in athletes-shooters in the process of ready position and target shooting

    Directory of Open Access Journals (Sweden)

    Pryimakov A.A.

    2015-02-01

    Full Text Available Purpose: consists in studying the relationships between the system of equilibrium regulation in upright stance and voluntary motion control in athletes-shooters during ready position and target shooting. Material: 19 highly skilled athletes specialized in pistol shooting were studied. Physiological and biomechanical characteristics of posture and voluntary motions were assessed by methods of stabilography, electromyography and tremorometry; besides, accuracy of target shooting was registered. Results: high degree of shooting accuracy dependence on posture somatic parameters has been revealed, of which the greatest impact upon the result is exerted by low-frequency vibrations of the body general centre of mass, subjected to voluntary control. Prognostic models of shooting accuracy dependence upon the character of posture regulation during ready position and the shot have been developed. Conclusions: obtained results reveal the mechanisms of functioning and interacting of two systems of management - posture and voluntary motion. Elaborated regression models permit to model and predict posture stability and shooting accuracy during ready position and the shot.

  13. Primogeniture and fertility: fertility models with unequal bequest.

    Science.gov (United States)

    Parsons, D O

    1984-01-01

    Models of the family which incorporate bequest inequality into the fertility decision were developed. Following a discussion on this topic by H.J. Habakkuk, discussion focuses on preindustrial and early industrial England and Western Europe. An attempt was made to develop fertility models which do not assume that all children are treated equally but instead recognize the special role that the eldest child often plays in the family. The fertility consequences of primogeniture are explored in 2 different fertility models. In the initial behavioral model due to Habakkuk, fertility is a function of marriage age and marriage age is a function of time required for one's capital to reach some social minimum required for household formation. In such a model it is possible to show that an increasingly unequal bequest between children will reduce aggregate fertility in the following generation. The introduction of explicit fertility choice considerably complicates the model. The effect of greater relative bequests to the eldest child, if motivated by parental preference, depends on the role children other than the eldest play in the family. If parents would normally choose to have more children the larger the total bequest they intend to bestow on all their children, the effect of primogeniture will be to reduce fertility. The wealth parents allocate to the eldest with primogeniture has an impact on the other children equivalent to a general decline in family bequests. Similar conclusions hold if the shift of wealth to the eldest is the result of a legal constraint that a specified share of the estate be allocated to the eldest. Yet, if the constraint is posed as a required proportionality between the wealth of the eldest and the average wealth of other children, the effect of primogeniture laws (or conversely equality laws) is ambiguous. The same negative wealth effect exists for the younger children as wealth is diverted to the eldest. A positive fertility effect also

  14. Fertilizer supply chain in Ethiopia: structure, performance and policy analysis

    Directory of Open Access Journals (Sweden)

    Johanes U.I. Agbahey

    2015-07-01

    Full Text Available In Ethiopia, less than 40% of farmers use fertilizer and those who do, apply rates significantly below those recommended. This low fertilizer use is primarily due to prices being two to three times higher than prices on the world markets. Reducing the price of fertilizer requires a sound understanding of the product´s supply chain. This study investigates whether fertilizer is delivered to farmers in an efficient way and at the lowest possible costs using an institutional economics framework. It was conducted in the Arsi zone and relied on secondary data as well as primary data collected through interviews. The findings point out the presence of several formal and informal institutions regulating the market. A market monopoly at each stage of the supply chain and a striking correspondence between the central organization of the chain and the rise in left-over stocks were observed. This pinpoints the imperfect structure of the chain and a misallocation of resources locked up in fertilizer stockholding. In order to improve the demand estimation procedure, this study suggests that incentives should be instituted to enhance the reliability of the information transferred along the process. Additionally, expert knowledge used in the process should be well documented, stock inventories should not be limited to central warehouses and stockholding needs to be reduced.

  15. Improvement of natural pastures using liquid organic fertilizers

    Science.gov (United States)

    Ghambashidze, Giorgi; Gabedava, Giorgi; Abuladze, Paata

    2016-04-01

    Nowadays natural pastures remains the main source to supply livestock with fresh feed material in Georgia. Due to that common pasturelands are under continues grazing pressure and normally no measures are taken in order to improve pasture productivity and to protect soil from erosion. Unregulated stocking rate leads to overutilization of natural pastures causing reduction in productivity and soil fertility. It is especially evident in arid regions, where bare soil after removal of vegetation dries out and is subject to wind erosion. In many areas even with regulated stocking rate plant available soil nutrient pool is already diminished and vegetation cannot be recovered easily after grazing. Therefore it is essential to improve soil fertility, which provide adequate amount of nutrients to plants to regenerate. Ongoing study aims to compare effect of different types of organic fertilizers on natural pastures in combination with pasture rotation scheme in order to maintain soil fertility and prepare the basis for its gradual improvement. Initial results shows positive impact of liquid organic fertilizers which increased aboveground biomass production by 200-300 kg per hectare.

  16. Voluntary agreements in the industrial sector in China

    Energy Technology Data Exchange (ETDEWEB)

    Price, Lynn; Worrell, Ernst; Sinton, Jonathan

    2003-03-31

    China faces a significant challenge in the years ahead to continue to provide essential materials and products for a rapidly-growing economy while addressing pressing environmental concerns. China's industrial sector is heavily dependent on the country's abundant, yet polluting, coal resources. While tremendous energy conservation and environmental protection achievements were realized in the industrial sector in the past, there remains a great gulf between the China's level of energy efficiency and that of the advanced countries of the world. Internationally, significant energy efficiency improvement in the industrial sector has been realized in a number of countries using an innovative policy mechanism called Voluntary Agreements. This paper describes international experience with Voluntary Agreements in the industrial sector as well as the development of a pilot program to test the use of such agreements with two steel mills in Shandong Province, China.

  17. Current concerns in involuntary and voluntary autobiographical memories

    DEFF Research Database (Denmark)

    Johannessen, Kim Berg; Berntsen, Dorthe

    2010-01-01

    Involuntary autobiographical memories are conscious memories of personal events that come to mind with no preceding attempts at retrieval. It is often assumed that such memories are closely related to current concerns - i.e., uncompleted personal goals. Here we examined involuntary versus voluntary...... (deliberately retrieved) autobiographical memories in relation to earlier registered current concerns measured by the Personal Concern Inventory (PCI; Cox & Klinger, 2000). We found no differences between involuntary and voluntary memories with regard to frequency or characteristics of current concern related...... contents. However, memories related to current concerns were rated as more central to the person's identity, life story and expectations for the future than non-concern related memories, irrespective of mode of recall. Depression and PTSD symptoms correlated positively with the proportion of current...

  18. Serious gaming and voluntary laparoscopic skills training: a multicenter study.

    Science.gov (United States)

    Verdaasdonk, E G G; Dankelman, J; Schijven, M P; Lange, J F; Wentink, M; Stassen, L P S

    2009-01-01

    This study assesses the issue of voluntary training of a standardized online competition (serious gaming) between surgical residents. Surgical residents were invited to join a competition on a virtual reality (VR) simulator for laparoscopic motor skills. A final score was calculated based on the task performance of three exercises and was presented to all the participants through an online database on the Internet. The resident with the best score would win a lap-top computer. During three months, 31 individuals from seven hospitals participated (22 surgical residents, 3 surgeons and six interns). A total of 777 scores were logged in the database. In order to out-perform others some participants scheduled themselves voluntarily for additional training. More attempts correlated with higher scores. The serious gaming concept may enhance voluntary skills training. Online data capturing could facilitate monitoring of skills progression in surgical trainees and enhance (VR) simulator validation.

  19. Voluntary Sleep Choice and Its Effects on Bayesian Decisions.

    Science.gov (United States)

    Dickinson, David L; Drummond, Sean P A; Dyche, Jeff

    2016-01-01

    This study examines whether voluntary sleep restriction at commonly experienced levels impacts decision making in a Bayesian choice task. Participants recruited were largely traditional age college students from a regional state university (n = 100) and a federal military academy (n = 99; n = 56 and 43, respectively, used in final analysis). Sleep was measured by actigraphy over a one-week period, followed by performance of a decision task. The task involved two sources of information, base rate odds and sample evidence, with subjects asked to make a probability judgment. Results found that subjects with nightly sleep sleep deprived = SD), relative to those with > 7 hr, placed less decision weight on new evidence, relative to base rate information, in making difficult choices. This result is strongest among female subjects. For easier choices, voluntary SD did not affect relative decision weights placed on the two sources of available information.

  20. Voluntary language switching in English-Spanish bilingual children

    Science.gov (United States)

    Gross, Megan; Kaushanskaya, Margarita

    2015-01-01

    Although bilingual children frequently switch between languages, the psycholinguistic mechanisms underlying the emerging ability to control language choice are unknown. We examined the mechanisms of voluntary language switching in English-Spanish bilingual children during a picture-naming task under two conditions: 1) single-language naming in English and in Spanish; 2) either-language naming, when the children could use whichever language they wanted. The mechanism of inhibitory control was examined by analyzing local switching costs and global mixing costs. The mechanism of lexical accessibility was examined by analyzing the properties of the items children chose to name in their non-dominant language. The children exhibited significant switching costs across both languages and asymmetrical mixing costs; they also switched into their non-dominant language most frequently on highly accessible items. These findings suggest that both lexical accessibility and inhibition contribute to language choice during voluntary language switching in children. PMID:26889376

  1. Fertilization and early seed formation.

    Science.gov (United States)

    Dumas, Christian; Rogowsky, Peter

    2008-10-01

    The double fertilization of flowering plants is a complex process, encompassing multiple steps. From its discovery more than a century ago, many useful descriptive approaches have been employed to better unveil specific steps/mechanisms. More recently, the development of an in vitro assay developed in our laboratory, has allowed a better understanding of this phenomenon. However, in vitro methods may show some limitations. The search for complementary strategies, especially with the search of mutants affected in the fertilization step allowed one to elucidate this critical and unique phenomenon in living organisms. Genes involved in pollen tube guidance or pollen discharge in synergids have been identified, as well as genes exhibiting differential expression in sperm, egg and central cells before and after fertilization. A calcium wave proved to correspond to the first cellular event seen after cytoplasmic fusion in the fertilized egg cell or zygote, which develops into a multi-cellular organism with an elaborate body plan. The development of the fertilized central cell into a nourishing tissue (endosperm) starts with the formation of the coenocyte, a multinuclear single cell unique in the plant kingdom, cellularization occurring later on. The balance of the paternal and maternal genomes, which is under the control of the FIS polycomb group complex, was found to be of the utmost importance for the successful development of the seed.

  2. Transition cow: interaction with fertility.

    Science.gov (United States)

    Formigoni, A; Trevisi, E

    2003-09-01

    In recent years a progressive worsening of fertility indices in dairy cow herds has been observed. Several factors (genetic, dietary and management) seem to be more related to poor fertility than milk yield level. The degree and the length of the energy deficit during the transition period are inversely related to reproductive indices (e.g. conception rate is fertility in several ways. Excess of rumen degradable proteins, apart from negative energy balance, negatively affects reproductive activity. Conversely, some nutrients (i.e. some polyunsaturated fatty acids or some amino acids) seem to show positive effects on fertility. Finally, the relationship between health status, often compromised during the transition period, and fertility efficiency is discussed. The release of cytokines seems to be related directly and indirectly (mainly by the change in usual hepatic metabolism to the malfunction of reproductive apparatus. Quick recovery of reproductive activity requires the adoption of strategies around calving to cover the higher environmental and nutritive requirements and to prevent disorders of any kind.

  3. Fertility preservation in Turner syndrome.

    Science.gov (United States)

    Grynberg, Michaël; Bidet, Maud; Benard, Julie; Poulain, Marine; Sonigo, Charlotte; Cédrin-Durnerin, Isabelle; Polak, Michel

    2016-01-01

    Premature ovarian insufficiency is a relatively rare condition that can appear early in life. In a non-negligible number of cases the ovarian dysfunction results from genetic diseases. Turner syndrome (TS), the most common sex chromosome abnormality in females, is associated with an inevitable premature exhaustion of the follicular stockpile. The possible or probable infertility is a major concern for TS patients and their parents, and physicians are often asked about possible options to preserve fertility. Unfortunately, there are no recommendations on fertility preservation in this group. The severely reduced follicle pool even during prepubertal life represents the major limit for fertility preservation and is the root of numerous questions regarding the competence of gametes or ovarian tissue crybanked. In addition, patients suffering from TS show higher than usual rates of spontaneous abortion, fetal anomaly, and maternal morbidity and mortality, which should be considered at the time of fertility preservation and before reutilization of the cryopreserved gametes. Apart from fulfillment of the desire of becoming genetic parents, TS patients may be potential candidates for egg donation, gestational surrogacy, and adoption. The present review discusses the different options for preserving female fertility in TS and the ethical questions raised by these approaches.

  4. Male fertility in cystic fibrosis.

    LENUS (Irish Health Repository)

    Chotirmall, S H

    2011-04-05

    Infertility rates among males with cystic fibrosis (CF) approximate 97%. No information is currently available within Ireland determining an understanding of fertility issues and the best methods of information provision to this specialized group. This study aimed to determine understanding and preferred approaches to information provision on fertility issues to Irish CF males. A Descriptive Study utilizing prospective coded questionnaires was mailed to a male CF cohort (n=50). Sections included demographics, fertility knowledge & investigation. Response rate was 16\\/50 (32%). All were aware that CF affected their fertility. More than two-thirds (n=11) were able to provide explanations whilst only one-third (n=5) provided the correct explanation. Significant numbers stated thoughts of marriage and a future family. Half have discussed fertility with a healthcare professional (HCP). Mean age of discussion was 21.9 years. One third preferred an earlier discussion. The commonest first source for information was written material which was also the preferred source. Three-quarters requested further information preferring again, written material. Significant gaps in sex education of Irish CF males exist. Discussion should be initiated by HCPs and centre-directed written material devised to address deficiencies.

  5. Social contact networks and disease eradicability under voluntary vaccination.

    Directory of Open Access Journals (Sweden)

    Ana Perisic

    2009-02-01

    Full Text Available Certain theories suggest that it should be difficult or impossible to eradicate a vaccine-preventable disease under voluntary vaccination: Herd immunity implies that the individual incentive to vaccinate disappears at high coverage levels. Historically, there have been examples of declining coverage for vaccines, such as MMR vaccine and whole-cell pertussis vaccine, that are consistent with this theory. On the other hand, smallpox was globally eradicated by 1980 despite voluntary vaccination policies in many jurisdictions. Previous modeling studies of the interplay between disease dynamics and individual vaccinating behavior have assumed that infection is transmitted in a homogeneously mixing population. By comparison, here we simulate transmission of a vaccine-preventable SEIR infection through a random, static contact network. Individuals choose whether to vaccinate based on infection risks from neighbors, and based on vaccine risks. When neighborhood size is small, rational vaccinating behavior results in rapid containment of the infection through voluntary ring vaccination. As neighborhood size increases (while the average force of infection is held constant, a threshold is reached beyond which the infection can break through partially vaccinated rings, percolating through the whole population and resulting in considerable epidemic final sizes and a large number vaccinated. The former outcome represents convergence between individually and socially optimal outcomes, whereas the latter represents their divergence, as observed in most models of individual vaccinating behavior that assume homogeneous mixing. Similar effects are observed in an extended model using smallpox-specific natural history and transmissibility assumptions. This work illustrates the significant qualitative differences between behavior-infection dynamics in discrete contact-structured populations versus continuous unstructured populations. This work also shows how disease

  6. Voluntary childlessness in marriage and family textbooks, 1950-2000.

    Science.gov (United States)

    Chancey, L; Dumais, S A

    2009-04-01

    We perform a content analysis of twenty marriage and family textbooks published between 1950 and 2000 to study how the voluntarily childless are presented in undergraduate courses. Throughout the time period studied, independence, pursuit of a career, and romance were prominent themes in the representation of voluntary childlessness. Other themes emerged specific to each decade - the 1950s portrayed parenthood as a challenge, while the 1990s concentrated on alleviating negative stereotypes of the voluntarily childless.

  7. MYOELECTRIC ALTERATIONS AFTER VOLUNTARY INDUCED HIGH - AND LOW - FREQUENCY FATIGUE

    Directory of Open Access Journals (Sweden)

    Vojko Strojnik

    2008-06-01

    Full Text Available The aim of the study was to find whether voluntary induced high- and low-frequency peripheral fatigue exhibit specific alteration in surface EMG signal (SEMG during evoked and maximum voluntary contractions. Ten male students of physical education performed 60 s long stretch-shortening cycle (SSC exercise with maximal intensity and 30 s long concentric (CON exercise with maximal intensity. To verify voluntary induced peripheral fatigue, knee torques during low- (T20 and high-frequency electrical stimulation (T100 of relaxed vastus lateralis muscle (VL were obtained. Contractile properties of the VL were measured with passive twitch and maximal voluntary knee extension test (MVC. Changes in M-waves and SEMG during MVC test were used to evaluate the differences in myoelectrical signals. T100/T20 ratio decreased by 10.9 ± 8.4 % (p < 0.01 after the SSC exercise and increased by 35.9 ± 17.5 % (p < 0.001 after the CON exercise. Significant SEMG changes were observed only after the CON exercise where peak to peak time of the M-waves increased by 9.2 ± 13.3 % (p < 0.06, SEMG amplitude during MVC increased by 32.9 ± 21.6 % (p < 0.001 and SEMG power spectrum median frequency decreased by 11.0 ± 10.5 % (p < 0.05. It is concluded that high frequency fatigue wasn't reflected in SEMG, however the SEMG changes after the CON seemed to reflect metabolic changes due to acidosis

  8. [Mandatory or voluntary vaccinations? Juridical and medico-legal aspects].

    Science.gov (United States)

    Molendini, L O; Zanetti, A; Buzzi, F

    2003-01-01

    The Italian juridical and legislative aspects of vaccination based on a compulsory system are presented considering the medico-legal questions. The prospective of a voluntary system, as anticipated by many normatives and other official documents, is examined. The experience of some local health authorities on cases of in observance of the vaccinal obligation are detailed Finally professional risks for vaccinal operators are examined and the need of specific guidelines for parents' consent to compulsory vaccination during infancy is prospected.

  9. Developing voluntary standards for district nurse education and practice.

    Science.gov (United States)

    Saunders, Mary

    2016-05-01

    This article charts the development of a project, funded by the Queen's Nursing Institute and Queen's Nursing Institute Scotland, to develop voluntary standards that reflect the contemporary and future practice of district nurses. The standards are designed to enhance, but not replace, the Nursing and Midwifery Council standards for district nurse specialist practice. The project encompassed the four UK countries and gathered data from a wide range of sources to inform the new standards that were launched in September 2015.

  10. Conditional vs. Voluntary Contribution Mechanism – An Experimental Study

    OpenAIRE

    Reischmann, Andreas

    2015-01-01

    The Conditional Contribution Mechanism for public good provision gives all agents the possibility to condition their contribution on the total level of contribution provided by all agents. In this experimental study the mechanism's performance is compared to the performance of the Voluntary Contribution Mechanism. In an environment with binary contribution and linear valuations subjects play the mechanisms in a repeated setting. The mechanisms are compared in one case of complete informati...

  11. Social contact networks and disease eradicability under voluntary vaccination.

    Science.gov (United States)

    Perisic, Ana; Bauch, Chris T

    2009-02-01

    Certain theories suggest that it should be difficult or impossible to eradicate a vaccine-preventable disease under voluntary vaccination: Herd immunity implies that the individual incentive to vaccinate disappears at high coverage levels. Historically, there have been examples of declining coverage for vaccines, such as MMR vaccine and whole-cell pertussis vaccine, that are consistent with this theory. On the other hand, smallpox was globally eradicated by 1980 despite voluntary vaccination policies in many jurisdictions. Previous modeling studies of the interplay between disease dynamics and individual vaccinating behavior have assumed that infection is transmitted in a homogeneously mixing population. By comparison, here we simulate transmission of a vaccine-preventable SEIR infection through a random, static contact network. Individuals choose whether to vaccinate based on infection risks from neighbors, and based on vaccine risks. When neighborhood size is small, rational vaccinating behavior results in rapid containment of the infection through voluntary ring vaccination. As neighborhood size increases (while the average force of infection is held constant), a threshold is reached beyond which the infection can break through partially vaccinated rings, percolating through the whole population and resulting in considerable epidemic final sizes and a large number vaccinated. The former outcome represents convergence between individually and socially optimal outcomes, whereas the latter represents their divergence, as observed in most models of individual vaccinating behavior that assume homogeneous mixing. Similar effects are observed in an extended model using smallpox-specific natural history and transmissibility assumptions. This work illustrates the significant qualitative differences between behavior-infection dynamics in discrete contact-structured populations versus continuous unstructured populations. This work also shows how disease eradicability in

  12. Combined application of neuromuscular electrical stimulation and voluntary muscular contractions.

    Science.gov (United States)

    Paillard, Thierry

    2008-01-01

    Electromyostimulation (EMS) and voluntary muscle contraction (VC) constitute different modes of muscle activation and induce different acute physiological effects on the neuromuscular system. Long-term application of each mode of muscle activation can produce different muscle adaptations. It seems theoretically possible to completely or partially cumulate the muscle adaptations induced by each mode of muscle activation applied separately. This work consisted of examining the literature concerning the muscle adaptations induced by long-term application of the combined technique (CT) [i.e. EMS is combined with VC - non-simultaneously] compared with VC and/or EMS alone in healthy subjects and/or athletes and in post-operative knee-injured subjects. In general, CT induced greater muscular adaptations than VC whether in sports training or rehabilitation. This efficiency would be due to the fact that CT can facilitate cumulative effects of training completely or partially induced by VC and EMS practiced alone. CT also provides a greater improvement of the performance of complex dynamic movements than VC. However, EMS cannot improve coordination between different agonistic and antagonistic muscles and thus does not facilitate learning the specific coordination of complex movements. Hence, EMS should be combined with specific sport training to generate neuromuscular adaptations, but also allow the adjustment of motor control during a voluntary movement. Likewise, in a therapeutic context, CT was particularly efficient to accelerate recovery of muscle contractility during a rehabilitation programme. Strength loss and atrophy inherent in a traumatism and/or a surgical operation would be more efficiently compensated with CT than with VC. Furthermore, CT also restored more functional abilities than VC. Finally, in a rehabilitation context, EMS is complementary to voluntary exercise because in the early phase of rehabilitation it elicits a strength increase, which is necessary

  13. ACOG Committee Opinion No. 583: predispute, voluntary, binding arbitration.

    Science.gov (United States)

    2014-01-01

    : Arbitration is a form of dispute resolution that is an alternative to 'taking a case to court.' Weighing the potential advantages and disadvantages, predispute arbitration may represent a valid alternative dispute resolution strategy for physicians and patients. When correctly prepared, contractual agreements between patients and physicians for predispute, voluntary, binding arbitration can satisfy both individual and societal needs and, at the same time, meet relevant ethical principles.

  14. Different non-profit regimes within voluntary organised recreational football - a Danish case

    DEFF Research Database (Denmark)

    Bennike, Søren; Ottesen, Laila

    2017-01-01

    positions have been building up for the last hundred years and are regulated by different laws and different societal discourses, creating institutional inertia due to path dependence. This system has shown to be sustainable, yet the context surrounding sport is changing creating a need for the involved...... actors to become innovative to embrace new challenges, rooted in sports participation patterns and sport policy. Against that backdrop, the research question is: What do different civil society positions mean to their relationship as “member clubs” and “interest organisation” and how does it affect...... of respectively the DFA, the regional country units and the clubs. Moreover a recently completed survey on voluntary football clubs in Denmark will contribute to the understanding. Keywords: Sports Organizations; Sports Clubs; Sport Policy; Civil Society...

  15. Voluntary reduction of trans-fatty acids in Latin America and the Caribbean: current situation.

    Science.gov (United States)

    Monge-Rojas, Rafael; Colón-Ramos, Uriyoán; Jacoby, Enrique; Mozaffarian, Dariush

    2011-02-01

    As part of the Pan American Health Organization/World Health Organization Trans-Fat-Free Americas initiative, 12 representatives from food industries in Latin America and the Caribbean signed a declaration stating their intention to voluntarily eliminate industrially produced trans-fatty acids (TFA) from the Americas. A year later, in order to document the extent of the voluntary reduction, each declarant was asked to describe all reformulations and reductions in the TFA content of their products. After up to six requests for data, only three declarants provided such information in detail, and three others offered an overall summary of their reformulations. Additionally, three declarants reported the barriers that limit this process: availability of oil substitutes, cost, and consumers' sensory acceptance. The content of TFA and saturated fat in the food supply in the Americas should be regulated and strictly monitored in order to adequately evaluate a reduction of TFA in the region.

  16. Global Phosphorus Fertilizer Market and National Policies: A Case Study Revisiting the 2008 Price Peak.

    Science.gov (United States)

    Khabarov, Nikolay; Obersteiner, Michael

    2017-01-01

    The commodity market super-cycle and food price crisis have been associated with rampant food insecurity and the Arab spring. A multitude of factors were identified as culprits for excessive volatility on the commodity markets. However, as it regards fertilizers, a clear attribution of market drivers explaining the emergence of extreme price events is still missing. In this paper, we provide a quantitative assessment of the price spike of the global phosphorus fertilizer market in 2008 focusing on diammonium phosphate (DAP). We find that fertilizer market policies in India, the largest global importer of phosphorus fertilizers and phosphate rock, turned out to be a major contributor to the global price spike. India doubled its import of P-fertilizer in 2008 at a time when prices doubled. The analysis of a wide set of factors pertinent to the 2008 price spike in phosphorus fertilizer market leads us to the discovery of a price spike magnification and triggering mechanisms. We find that the price spike was magnified on the one hand by protective trade measures of fertilizer suppliers leading to a 19% drop in global phosphate fertilizer export. On the other hand, the Indian fertilizer subsidy scheme led to farmers not adjusting their demand for fertilizer. The triggering mechanism appeared to be the Indian production outage of P-fertilizer resulting in the additional import demand for DAP in size of about 20% of annual global supply. The main conclusion is that these three factors have jointly caused the spike, underscoring the need for ex ante improvements in fertilizer market regulation on both national and international levels.

  17. High-speed camera characterization of voluntary eye blinking kinematics.

    Science.gov (United States)

    Kwon, Kyung-Ah; Shipley, Rebecca J; Edirisinghe, Mohan; Ezra, Daniel G; Rose, Geoff; Best, Serena M; Cameron, Ruth E

    2013-08-01

    Blinking is vital to maintain the integrity of the ocular surface and its characteristics such as blink duration and speed can vary significantly, depending on the health of the eyes. The blink is so rapid that special techniques are required to characterize it. In this study, a high-speed camera was used to record and characterize voluntary blinking. The blinking motion of 25 healthy volunteers was recorded at 600 frames per second. Master curves for the palpebral aperture and blinking speed were constructed using palpebral aperture versus time data taken from the high-speed camera recordings, which show that one blink can be divided into four phases; closing, closed, early opening and late opening. Analysis of data from the high-speed camera images was used to calculate the palpebral aperture, peak blinking speed, average blinking speed and duration of voluntary blinking and compare it with data generated by other methods previously used to evaluate voluntary blinking. The advantages of the high-speed camera method over the others are discussed, thereby supporting the high potential usefulness of the method in clinical research.

  18. Voluntary Saccadic Eye Movements Ride the Attentional Rhythm.

    Science.gov (United States)

    Hogendoorn, Hinze

    2016-10-01

    Visual perception seems continuous, but recent evidence suggests that the underlying perceptual mechanisms are in fact periodic-particularly visual attention. Because visual attention is closely linked to the preparation of saccadic eye movements, the question arises how periodic attentional processes interact with the preparation and execution of voluntary saccades. In two experiments, human observers made voluntary saccades between two placeholders, monitoring each one for the presentation of a threshold-level target. Detection performance was evaluated as a function of latency with respect to saccade landing. The time course of detection performance revealed oscillations at around 4 Hz both before the saccade at the saccade origin and after the saccade at the saccade destination. Furthermore, oscillations before and after the saccade were in phase, meaning that the saccade did not disrupt or reset the ongoing attentional rhythm. Instead, it seems that voluntary saccades are executed as part of an ongoing attentional rhythm, with the eyes in flight during the troughs of the attentional wave. This finding for the first time demonstrates that periodic attentional mechanisms affect not only perception but also overt motor behavior.

  19. Preliminary study: voluntary food intake in dogs during tryptophan supplementation.

    Science.gov (United States)

    Fragua, Víctor; González-Ortiz, Gemma; Villaverde, Cecilia; Hervera, Marta; Mariotti, Valentina Maria; Manteca, Xavier; Baucells, María Dolores

    2011-10-01

    Tryptophan, a precursor of important molecules such as serotonin, melatonin and niacin, is an essential amino acid for dogs. In pigs, tryptophan supplementation has been shown to induce a significant increase in food intake. The aim of the present study was to assess whether long-term tryptophan supplementation increases voluntary food intake in dogs and to observe whether this was accompanied by a change in serum ghrelin. In the present study, sixteen adult Beagle dogs were used, with four male and four female dogs fed diets supplemented with tryptophan (1 g/dog per d) during 81 d (Trp) and four male and four female dogs that were not supplemented (control). A voluntary food intake test was performed during 5 d following the supplementation period. The Trp group tended to show a higher food intake during the voluntary food intake test (58.0 (SE 5.37) v. 77.5 (SE 3.65) g/kg metabolic weight per d; P = 0.074). No significant differences were found for serum ghrelin concentrations.

  20. Modulation in voluntary neural drive in relation to muscle soreness

    Science.gov (United States)

    Bringard, A.; Puchaux, K.; Noakes, T. D.; Perrey, S.

    2007-01-01

    The aim of this study was to investigate whether (1) spinal modulation would change after non-exhausting eccentric exercise of the plantar flexor muscles that produced muscle soreness and (2) central modulation of the motor command would be linked to the development of muscle soreness. Ten healthy subjects volunteered to perform a single bout of backward downhill walking exercise (duration 30 min, velocity 1 ms−1, negative grade −25%, load 12% of body weight). Neuromuscular test sessions [H-reflex, M-wave, maximal voluntary torque (MVT)] were performed before, immediately after, as well as 1–3 days after the exercise bout. Immediately after exercise there was a −15% decrease in MVT of the plantar flexors partly attributable to an alteration in contractile properties (−23% in electrically evoked mechanical twitch). However, MVT failed to recover before the third day whereas the contractile properties had significantly recovered within the first day. This delayed recovery of MVT was likely related to a decrement in voluntary muscle drive. The decrease in voluntary activation occurred in the absence of any variation in spinal modulation estimated from the H-reflex. Our findings suggest the development of a supraspinal modulation perhaps linked to the presence of muscle soreness. PMID:17978834

  1. Increased Skeletal Muscle GLUT4 Expression in Obese Mice After Voluntary Wheel Running Exercise Is Posttranscriptional.

    Science.gov (United States)

    Gurley, Jami M; Griesel, Beth A; Olson, Ann Louise

    2016-10-01

    Exercise promotes glucose clearance by increasing skeletal muscle GLUT4-mediated glucose uptake. Importantly, exercise upregulates muscle GLUT4 expression in an insulin-independent manner under conditions of insulin resistance, such as with type 2 diabetes. However, the insulin-independent mechanism responsible for rescued muscle GLUT4 expression is poorly understood. We used voluntary wheel running (VWR) in mice to test the prevailing hypothesis that insulin-independent upregulation of skeletal muscle GLUT4 protein expression with exercise is through increased Glut4 transcription. We demonstrate that 4 weeks of VWR exercise in obese mice rescued high-fat diet-induced decreased muscle GLUT4 protein and improved both fasting plasma insulin and hepatic triacylglyceride levels, but did not rescue muscle Glut4 mRNA. Persistent reduction in Glut4 mRNA suggests that a posttranscriptional mechanism regulated insulin-independent muscle GLUT4 protein expression in response to exercise in lean and obese mice. Reduction of GLUT4 protein in sedentary animals upon treatment with rapamycin revealed mTORC1-dependent GLUT4 regulation. However, no difference in GLUT4 protein expression was observed in VWR-exercised mice treated with either rapamycin or Torin 1, indicating that exercise-dependent regulation on GLUT4 was mTOR independent. The findings provide new insight into the mechanisms responsible for exercise-dependent regulation of GLUT4 in muscle.

  2. Voluntary organ donation system adapted to Chinese cultural values and social reality.

    Science.gov (United States)

    Huang, Jiefu; Millis, J Michael; Mao, Yilei; Millis, M Andrew; Sang, Xinting; Zhong, Shouxian

    2015-04-01

    Organ donation and transplant systems have unique characteristics based on the local culture and socioeconomic context. China's transplant and organ donation systems developed without regulatory oversight until 2006 when regulation and policy were developed and then implemented over the next several years. Most recently, the pilot project of establishing a voluntary citizen-based deceased donor program was established. The pilot program addressed the legal, financial, and cultural barriers to organ donation in China. The pilot program has evolved into a national program. Significantly, it established a uniquely Chinese donor classification system. The Chinese donor classification system recognizes donation after brain death (category I), donation after circulatory death (category II), and donation after brain death followed by circulatory death (category III). Through August 2014, the system has identified 2326 donors and provided 6416 organs that have been allocated though a transparent organ allocation system. The estimated number of donors in 2014 is 1147. As China's attitudes toward organ donation have matured and evolved and as China, as a nation, is taking its place on the world stage, it is recognizing that its past practice of using organs from executed prisoners is not sustainable. It is time to recognize that the efforts to regulate transplantation and provide voluntary citizen-based deceased organ donation have been successful and that China should use this system to provide organs for all transplants in every province and hospital in China. At the national organ transplant congress on October 30, 2014, the Chairman of the China's national organ donation and transplantation committee, Jeifu Huang required all hospitals to stop using organs from executed prisoners immediately and the civilian organ donation will be sole source for organ transplant in China starting January 2015. © 2015 American Association for the Study of Liver Diseases.

  3. Crystallographic properties of fertilizer compounds

    Energy Technology Data Exchange (ETDEWEB)

    Frazier, A.W.; Dillard, E.F.; Thrasher, R.D.; Waerstad, K.R.; Hunter, S.R.; Kohler, J.J.; Scheib, R.M.

    1991-02-01

    This bulletin is a compilation of crystallographic data collected at NFERC on 450 fertilizer-related compounds. In TVA's fertilizer R and D program, petrographic examination, XRD, and infrared spectroscopy are combined with conventional chemical analysis methods in identifying the individual compounds that occur in fertilizer materials. This handbook brings together the results of these characterization studies and supplemental crystallographic data from the literature. It is in one-compound-per-page, loose-leaf format, ordered alphabetically by IUPAC name. Indexes provided include IUPAC name, formula, group, alternate formula, synonyms, x-ray data, optical data. Tables are given for solids, compounds in commercial MAP and DAP, and matrix materials in phosphate rock.

  4. Polyamines in Pollen: From Microsporogenesis to Fertilization

    Science.gov (United States)

    Aloisi, Iris; Cai, Giampiero; Serafini-Fracassini, Donatella; Del Duca, Stefano

    2016-01-01

    The entire pollen life span is driven by polyamine (PA) homeostasis, achieved through fine regulation of their biosynthesis, oxidation, conjugation, compartmentalization, uptake, and release. The critical role of PAs, from microsporogenesis to pollen–pistil interaction during fertilization, is suggested by high and dynamic transcript levels of PA biosynthetic genes, as well as by the activities of the corresponding enzymes. Moreover, exogenous supply of PAs strongly affects pollen maturation and pollen tube elongation. A reduction of endogenous free PAs impacts pollen viability both in the early stages of pollen development and during fertilization. A number of studies have demonstrated that PAs largely function by modulating transcription, by structuring pollen cell wall, by modulating protein (mainly cytoskeletal) assembly as well as by modulating the level of reactive oxygen species. Both free low-molecular weight aliphatic PAs, and PAs conjugated to proteins and hydroxyl-cinnamic acids take part in these complex processes. Here, we review both historical and recent evidence regarding molecular events underlying the role of PAs during pollen development. In the concluding remarks, the outstanding issues and directions for future research that will further clarify our understanding of PA involvement during pollen life are outlined. PMID:26925074

  5. Polyamines in Pollen: From Microsporogenesis to Fertilization.

    Science.gov (United States)

    Aloisi, Iris; Cai, Giampiero; Serafini-Fracassini, Donatella; Del Duca, Stefano

    2016-01-01

    The entire pollen life span is driven by polyamine (PA) homeostasis, achieved through fine regulation of their biosynthesis, oxidation, conjugation, compartmentalization, uptake, and release. The critical role of PAs, from microsporogenesis to pollen-pistil interaction during fertilization, is suggested by high and dynamic transcript levels of PA biosynthetic genes, as well as by the activities of the corresponding enzymes. Moreover, exogenous supply of PAs strongly affects pollen maturation and pollen tube elongation. A reduction of endogenous free PAs impacts pollen viability both in the early stages of pollen development and during fertilization. A number of studies have demonstrated that PAs largely function by modulating transcription, by structuring pollen cell wall, by modulating protein (mainly cytoskeletal) assembly as well as by modulating the level of reactive oxygen species. Both free low-molecular weight aliphatic PAs, and PAs conjugated to proteins and hydroxyl-cinnamic acids take part in these complex processes. Here, we review both historical and recent evidence regarding molecular events underlying the role of PAs during pollen development. In the concluding remarks, the outstanding issues and directions for future research that will further clarify our understanding of PA involvement during pollen life are outlined.

  6. 植物生长调节剂和肥料混施对沟叶结缕草越冬期生长和抗性生理的影响%Effect of mixed application of growth regulators and fertilizers on the growth, cold-resistance and physiology of turfgrass Zoysia matrella in wintering period

    Institute of Scientific and Technical Information of China (English)

    胡宏友; 李雄

    2009-01-01

    In addressing the problem of warm-season turfgrass withering during winter, the turfgrass species Zoysia matrella was treated with growth regulators, fast-released fertilizers and organic fertilizers in L_9(3~4) orthogonal test. Compared with the control, leaf LAI, chlorophyll, free proline and soluble sugar of the treatments significantly improve. Also, the activities of root and of antioxidant enzymes of SOD, POD and CAT improve, whereas malondialdehyde (MDA) content decreases significantly. Hence the growth, cold-resistance ability and landscape quality of turfgrass during winter under the treatments are significantly enhanced. Range analysis indicates that the effective factors vary with different test indexes, implying that plant growth regulators and fertilizers are complementary in promoting growth and enhancing physiological functions of turfgrass in winter. For an improved integrated quality of Z. matrella turfgrass in winter, an optimum formula is proposed based on comprehensive analysis of the growth and cold-resistance stress indexes. The proposed optimum formula is: liquid fertilizer, containing paclobutrazol, triacontanol, sulphate-potassium magnesium, urea and chitosan at 300 mg · L~(-1), 2 mg · L~(-1), 1 500 mg · L~(-1), 1 000 mg ·L~(-1) and 1 000 mg ·L~(-1) respectively. This should be applied to the turfgrass by foliage spray at 200 mL ·m~(-2), and then peanut cake broadcasted at 90 g · m~(-2).%为解决暖季型草坪草越冬期枯黄的问题,以沟叶结缕草为材料,利用L_9(3~4)正交试验设计方法设计了植物生长调节剂、速效肥与有机肥3因子3水平正交混施试验.与清水对照相比,处理组沟叶结缕草叶面积指数、叶绿素含量、叶片游离脯氨酸和可溶性糖含量均显著提高,且根系活性、叶片抗氧化酶系(SOD、POD、CAT)活性显著增加,叶片丙二醛含量则显著降低.处理组整体上提高了草坪草越冬期的生长及抗冷性能,显著改善了草坪草的

  7. Fertility potential after unilateral orchiopexy

    DEFF Research Database (Denmark)

    Cortes, D; Thorup, J M; Lindenberg, S

    1996-01-01

    similar fertility potentials were found in adulthood. Five of the 65 patients (7.7%, 95% confidence limits 2.5 to 17%) may experience infertility, representing 33% of both groups with less than 1% of the age matched number of spermatogonia per tubular transverse section (approximately no germ cells......) in the biopsy specimen at orchiopexy. CONCLUSIONS: Between ages 2 and 12 years the timing of unilateral orchiopexy may vary without an effect on subsequent fertility potential. When biopsy at surgery lacks germ cells, there is an approximately 33% age independent risk of subsequent infertility. Otherwise...

  8. Repeatability of maximal voluntary force and of surface EMG variables during voluntary isometric contraction of quadriceps muscles in healthy subjects.

    Science.gov (United States)

    Rainoldi, A; Bullock-Saxton, J E; Cavarretta, F; Hogan, N

    2001-12-01

    The repeatability of initial values and rate of change of EMG signal mean spectral frequency (MNF), average rectified values (ARV), muscle fiber conduction velocity (CV) and maximal voluntary contraction (MVC) was investigated in the vastus medialis obliquus (VMO) and vastus lateralis (VL) muscles of both legs of nine healthy male subjects during voluntary, isometric contractions sustained for 50 s at 50% MVC. The values of MVC were recorded for both legs three times on each day and for three subsequent days, while the EMG signals have been recorded twice a day for three subsequent days. The degree of repeatability was investigated using the Fisher test based upon the ANalysis Of VAriance (ANOVA), the Standard Error of the Mean (SEM) and the Intraclass Correlation Coefficient (ICC). Data collected showed a high level of repeatability of MVC measurement (normalized SEM from 1.1% to 6.4% of the mean). MNF and ARV initial values also showed a high level of repeatability (ICC>70% for all muscles and legs except right VMO). At 50% MVC level no relevant pattern of fatigue was observed for the VMO and VL muscles, suggesting that other portions of the quadriceps might have contributed to the generated effort. These observations seem to suggest that in the investigation of muscles belonging to a multi-muscular group at submaximal level, the more selective electrically elicited contractions should be preferred to voluntary contractions.

  9. Effectiveness and legitimacy of forest carbon standards in the OTC voluntary carbon market

    Directory of Open Access Journals (Sweden)

    Merger Eduard

    2011-08-01

    Full Text Available Abstract Background In recent years, the voluntary over-the-counter (OTC carbon market has reached a significant market volume. It is particularly interesting for forest mitigation projects which are either ineligible in compliance markets or confronted with a plethora of technical and financial hurdles and lacking market demand. As the OTC market is not regulated, voluntary standards have been created to secure the social and environmental integrity of the traded mitigation projects and thus to ensure the quality of the resulting carbon credits. Building on a theoretical efficiency-legitimacy framework, this study aims to identify and analyse the characteristics and indicators that determine the efficiency and organisational legitimacy of standards for afforestation/reforestation carbon projects. Results All interviewed market actors consider third-party certification and standards as a crucial component of market functionality, which provide quality assurance mechanisms that reduce information asymmetries and moral hazard between the actors regarding the quality of carbon credits, and thus reduce transaction costs. Despite this development, the recent evolution of many new and differing standards is seen as a major obstacle that renders it difficult for project developers and buyers to select an appropriate standard. According to the interviewed experts the most important legitimating factors of standards are assurance of a sufficient level of quality of carbon credits, scientifically substantiated methodological accounting and independent third-party verification, independence of standard bodies, transparency, wide market acceptance, back-up of the wider community including experts and NGOs, rigorous procedures, and the resemblance to the Afforestation/Reforestation (A/R CDM due to its international policy endorsements. In addition, standards must provide evidence that projects contribute to a positive social and environmental development, do

  10. Effectiveness and legitimacy of forest carbon standards in the OTC voluntary carbon market.

    Science.gov (United States)

    Merger, Eduard; Pistorius, Till

    2011-08-17

    In recent years, the voluntary over-the-counter (OTC) carbon market has reached a significant market volume. It is particularly interesting for forest mitigation projects which are either ineligible in compliance markets or confronted with a plethora of technical and financial hurdles and lacking market demand. As the OTC market is not regulated, voluntary standards have been created to secure the social and environmental integrity of the traded mitigation projects and thus to ensure the quality of the resulting carbon credits. Building on a theoretical efficiency-legitimacy framework, this study aims to identify and analyse the characteristics and indicators that determine the efficiency and organisational legitimacy of standards for afforestation/reforestation carbon projects. All interviewed market actors consider third-party certification and standards as a crucial component of market functionality, which provide quality assurance mechanisms that reduce information asymmetries and moral hazard between the actors regarding the quality of carbon credits, and thus reduce transaction costs. Despite this development, the recent evolution of many new and differing standards is seen as a major obstacle that renders it difficult for project developers and buyers to select an appropriate standard. According to the interviewed experts the most important legitimating factors of standards are assurance of a sufficient level of quality of carbon credits, scientifically substantiated methodological accounting and independent third-party verification, independence of standard bodies, transparency, wide market acceptance, back-up of the wider community including experts and NGOs, rigorous procedures, and the resemblance to the Afforestation/Reforestation (A/R) CDM due to its international policy endorsements. In addition, standards must provide evidence that projects contribute to a positive social and environmental development, do no harm as a minimum requirement and build a

  11. Soil Fertility Status on Organic Paddy Experiment

    Directory of Open Access Journals (Sweden)

    Mujiyo

    2015-07-01

    Full Text Available The study aims to determine fertility status of the soil after organic paddy experiments using kinds and doses of organic fertilizers. Experiment was conducted at greenhouse laboratory in Faculty of Agriculture Sebelas Maret University Surakarta. Experimental design used completely randomized design with 9 kinds of treatment was replicated 3 times. Experiments were the use of cow manure, Azolla fertilizer, Azolla inoculum and its combinations that are based on fulfilling nutrient requirements of 120 kg N ha-1. Result shows that the use of cow manure, Azolla fertilizers and Azolla inoculum had no effect on changes of soil fertility status. Soil fertility status was not significantly correlated with cow manure (0,16ns, Azolla fertilizer (0,26ns and Azolla inoculum (0,16ns. Average of final soil fertility status included fertile category, which was similar as the initial soil fertility status. Average of final soil properties of treatment but nevertheless was relatively higher than in no treatment, indicating the use of cow manure, Azolla fertilizer, Azolla inoculum and its combinations had greater impact to soil properties. Cow manure despite increased available K2O and dry grain, but it did not significantly increase the soil fertility status from fertile to very fertile. This was presumably due to the relatively short experiment period, only one planting season had not given significant effect to soil properties. Implication of this study is the use of cow manure, Azolla fertilizer, Azolla inoculum and its combinations although did not increase the soil fertility status but could maintain soil fertility status as the initial conditions before planting.

  12. Fertility potential after unilateral orchiopexy

    DEFF Research Database (Denmark)

    Cortes, D; Thorup, J M; Lindenberg, S

    1996-01-01

    ) in the biopsy specimen at orchiopexy. CONCLUSIONS: Between ages 2 and 12 years the timing of unilateral orchiopexy may vary without an effect on subsequent fertility potential. When biopsy at surgery lacks germ cells, there is an approximately 33% age independent risk of subsequent infertility. Otherwise...

  13. Socioeconomic status and fertility decline

    DEFF Research Database (Denmark)

    Dribe, Martin; Breschi, Marco; Gagnon, Alain

    2017-01-01

    The timings of historical fertility transitions in different regions are well understood by demographers, but much less is known regarding their specific features and causes. In the study reported in this paper, we used longitudinal micro-level data for five local populations in Europe and North ...

  14. Fertility potential after unilateral orchiopexy

    DEFF Research Database (Denmark)

    Cortes, D; Thorup, J M; Lindenberg, S

    1996-01-01

    PURPOSE: We evaluated whether adult fertility potential was better when unilateral orchiopexy was done at ages 2 to 6 years or later, and we identified those at risk for infertility. MATERIALS AND METHODS: Unilateral orchiopexy was performed simultaneously with testicular biopsy in 11 patients 2....

  15. France: High and stable fertility

    Directory of Open Access Journals (Sweden)

    Clémentine Rossier

    2008-07-01

    Full Text Available The current total fertility rate in France is around 1.9 children per woman. This is a relatively high level by current European standards and makes France an outlier, despite the fact that its other demographic trends, especially conjugal behaviour, and social and economic trends are not very different from other Western European countries. France can serve as a counterfactual test case for some of the hypotheses advanced to explain the current low level of fertility in most European countries (delay in fertility, decline in marriage, increased birth control, greater economic uncertainty. France's fertility level can be partly explained by its active family policy introduced after the Second World War, and adapted in the 1980s to accommodate women's entry into the labour force. This policy is the result of a battle, fuelled by pro-natalism, between the conservative supporters of family values and the promoters of state-supported individual equality. French family policy thus encompasses a wide range of measures based on varying ideological backgrounds, and it is difficult to classify in comparison to the more precisely focused family policies of other European welfare states. The active family policy seems to have created especially positive attitudes towards two- or three child families in France.

  16. Strong families and declining fertility

    NARCIS (Netherlands)

    Hilevych, Yuliya

    2016-01-01

    This dissertation focuses on the role of family and social relationships in individuals’ reproductive careers during the fertility decline in Soviet Ukraine from around 1950 to 1975. These three decades after the Second World War signified the end of the First Demographic Transition in Ukraine

  17. The Cost of Raising Fertility

    DEFF Research Database (Denmark)

    Kurjanska, Malgorzata; Lyngsie, Jacob

    supporting an increase in Europe’s fertility rate, increasing maternity leave may also exacerbate gender inequalities tied to childrearing. Relying on alternative measures of in-home gender inequalities (e.g. gender conservatism), initial results provide compelling evidence that maternity benefits do affect...

  18. Fertility potential after unilateral orchiopexy

    DEFF Research Database (Denmark)

    Cortes, D; Thorup, J M; Lindenberg, S

    1996-01-01

    PURPOSE: We evaluated whether adult fertility potential was better when unilateral orchiopexy was done at ages 2 to 6 years or later, and we identified those at risk for infertility. MATERIALS AND METHODS: Unilateral orchiopexy was performed simultaneously with testicular biopsy in 11 patients 2...

  19. (AJST) PEDOLOGICAL CHARACTERISTICS, GENERAL FERTILITY ...

    African Journals Online (AJOL)

    Administrator

    Department of Soil Science, P.O. Box 3008, Morogoro, TANZANIA. 2Graduate ... 3Center for Cooperative Research and Development, Kobe University, ... Key words: Pedological characteristics, fertility, soil classification, benchmark soils, Morogoro. District .... density was determined using core sample method (Blake,.

  20. Mycorrhizas and tropical soil fertility

    NARCIS (Netherlands)

    Cardoso, I.M.; Kuyper, T.W.

    2006-01-01

    Major factors that constrain tropical soil fertility and sustainable agriculture are low nutrient capital, moisture stress, erosion, high P fixation, high acidity with aluminium toxicity, and low soil biodiversity. The fragility of many tropical soils limits food production in annual cropping system

  1. Mycorrhizas and tropical soil fertility

    NARCIS (Netherlands)

    Cardoso, I.M.; Kuyper, T.W.

    2006-01-01

    Major factors that constrain tropical soil fertility and sustainable agriculture are low nutrient capital, moisture stress, erosion, high P fixation, high acidity with aluminium toxicity, and low soil biodiversity. The fragility of many tropical soils limits food production in annual cropping system

  2. Fertilization Mechanisms in Flowering Plants.

    Science.gov (United States)

    Dresselhaus, Thomas; Sprunck, Stefanie; Wessel, Gary M

    2016-02-08

    Compared with the animal kingdom, fertilization is particularly complex in flowering plants (angiosperms). Sperm cells of angiosperms have lost their motility and require transportation as a passive cargo by the pollen tube cell to the egg apparatus (egg cell and accessory synergid cells). Sperm cell release from the pollen tube occurs after intensive communication between the pollen tube cell and the receptive synergid, culminating in the lysis of both interaction partners. Following release of the two sperm cells, they interact and fuse with two dimorphic female gametes (the egg and the central cell) forming the major seed components embryo and endosperm, respectively. This process is known as double fertilization. Here, we review the current understanding of the processes of sperm cell reception, gamete interaction, their pre-fertilization activation and fusion, as well as the mechanisms plants use to prevent the fusion of egg cells with multiple sperm cells. The role of Ca(2+) is highlighted in these various processes and comparisons are drawn between fertilization mechanisms in flowering plants and other eukaryotes, including mammals.

  3. Fertilization Mechanisms in Flowering Plants

    Science.gov (United States)

    Dresselhaus, Thomas; Sprunck, Stefanie; Wessel, Gary M.

    2016-01-01

    Compared to the animal kingdom, fertilization is particularly complex in flowering plants (angiosperms). Sperm cells of angiosperms have lost their motility and require transportation as a passive cargo by the pollen tube cell to the egg apparatus (egg cell and accessory synergid cells). Sperm cell release from the pollen tube occurs after intensive communication between the pollen tube cell and the receptive synergid, culminating in the lysis of both interaction partners. Following release of the two sperm cells they interact and fuse with two dimorphic female gametes (egg and central cell) forming the major seed components embryo and endosperm, respectively. This process is known as double fertilization. Here we review the current understanding of the processes of sperm cell reception, gamete interaction, their pre-fertilization activation and fusion as well as the mechanisms plants use to prevent the fusion of egg cells with multiple sperm cells. The role of Ca2+ is highlighted in these various processes and comparisons are drawn between fertilization mechanisms in flowering plants and other eukaryotes including mammals. PMID:26859271

  4. CURTAILING FERTILIZER SCARCITY AND CLIMATE CHANGE; AN ...

    African Journals Online (AJOL)

    Osondu

    2012-05-29

    May 29, 2012 ... on average thereby using very low rates of chemical fertilizers. Organic materials used by ... The fertilizer issue is more so, considering the current global food ... use profitability through higher commodity prices received by ...

  5. Children Procedures and Treatment (Fertility Issues)

    Medline Plus

    Full Text Available ... Story Share my story! Children Procedures and Treatment Is ovarian tissue cryopreservation available to girls under 18? ... fertility preservation with their cancer-stricken child? How is the Oncofertility Consortium addressing the fertility preservation needs ...

  6. Psychological aspects of male fertility treatment

    DEFF Research Database (Denmark)

    Mikkelsen, Alice Toft; Madsen, Svend Aage; Humaidan, Peter

    2013-01-01

    To explore and to identify the possible need for psychological communicative support in men undergoing fertility treatment.......To explore and to identify the possible need for psychological communicative support in men undergoing fertility treatment....

  7. Fertility preservation after chemotherapy for Hodgkin lymphoma

    NARCIS (Netherlands)

    van der Kaaij, Marleen A. E.; van Echten-Arends, Jannie; Simons, Arnold H. M.; Kluin-Nelemans, Hanneke C.

    2010-01-01

    Treatment for Hodgkin lymphoma can negatively affect fertility. This review summarizes data on fertility after chemotherapy in adult patients. Alkylating chemotherapy, especially if containing procarbazine and/or cyclophosphamide, is most harmful to gonadal functioning. Alkylating regimens cause pro

  8. Understanding fertilization through intracytoplasmic sperm injection (ICSI)

    Science.gov (United States)

    Neri, Queenie V.; Lee, Bora; Rosenwaks, Zev; Machaca, Khaled; Palermo, Gianpiero D.

    2014-01-01

    Summary Since the establishment of in vitro fertilization, it became evident that almost half of the couples failed to achieve fertilization and this phenomenon was attributed to a male gamete dysfunction. The adoption of assisted fertilization techniques particularly ICSI has been able to alleviate male factor infertility by granting the consistent ability of a viable spermatozoon to activate an oocyte. Single sperm injection, by pinpointing the beginning of fertilization, has been an invaluable tool in clarifying the different aspects of early fertilization and syngamy. However, even with ICSI some couples fail to fertilize due to ooplasmic dysmaturity in relation to the achieved nuclear maturation marked by the extrusion of the first polar body. More uncommon are cases where the spermatozoa partially or completely lack the specific oocyte activating factor. In this work, we review the most relevant aspects of fertilization and its failure through assisted reproductive technologies. Attempts at diagnosing and treating clinical fertilization failure are described. PMID:24290744

  9. Implications of carbon cap-and-trade for US voluntary renewable energy markets

    Energy Technology Data Exchange (ETDEWEB)

    Bird, Lori A. [National Renewable Energy Laboratory, 1617 Cole Boulevard, Golden, CO 80401 (United States); Holt, Edward [Ed Holt and Associates, Inc., 28 Headland Road, Harpswell, ME 04079-2923 (United States); Levenstein Carroll, Ghita [University of Colorado at Boulder, 3315 Folsom Street, Boulder, CO 80304 (United States)

    2008-06-15

    Many consumers today are purchasing renewable energy in large part for the greenhouse gas (GHG) emissions benefits that they provide. Emerging carbon regulation in the US has the potential to affect existing markets for renewable energy. Carbon cap-and-trade programs are now under development in the Northeast under the Regional Greenhouse Gas Initiative (RGGI) and in early stages of development in the West and Midwest. There is increasing discussion about carbon regulation at the national level as well. While renewable energy will likely benefit from carbon cap-and-trade programs because compliance with the cap will increase the costs of fossil fuel generation, cap-and-trade programs can also impact the ability of renewable energy generation to affect overall CO{sub 2} emissions levels and obtain value for those emissions benefits. This paper summarizes key issues for renewable energy markets that are emerging with carbon regulation, such as the implications for emissions benefits claims and voluntary market demand and the use of renewable energy certificates (RECs) in multiple markets. It also explores policy options under consideration for designing carbon policies to enable carbon markets and renewable energy markets to work together. (author)

  10. Early alterations in soleus GLUT-4, glucose transport, and glycogen in voluntary running rats

    Science.gov (United States)

    Henriksen, Erik J.; Halseth, Amy E.

    1994-01-01

    Voluntary wheel running (WR) by juvenile female rats was used as a noninterventional model of soleus muscle functional overload to study the regulation of insulin-stimulated glucose transport activity by the glucose transporter (GLUT-4 isoform) protein level and glycogen concentration. Soleus total protein content was significantly greater (+18%;P greater than 0.05) than in age-matched controls after 1 wk of WR, and this hypertrophic response continued in weeks 2-4 (+24-32%). GLUT-4 protein was 39% greater than in controls in 1-wk WR soleus, and this adaptation was accompanied by a similar increase in in vitro insulin-stimulated glucose transport activity(+29%). After 2 and 4 wk of WR, however, insulin-stimulated glucose transport activity had returned to control levels, despite a continued elevation (+25-28%) of GLUT-4 protein. At these two time points, glycogen concentration was significantly enhanced in WR soleus (+21-42%), which coincided with significant reductions in glycogen synthase activity ratios (-23 to-41%). These results indicate that, in this model of soleus muscle functional overload, the GLUT-4 protein level may initially regulate insulin-stimulated glucose transport activity in the absence of changes in other modifying factors. However,this regulation of glucose transport activity by GLUT-4 protein may be subsequently overridden by elevated glycogen concentration.

  11. Children Procedures and Treatment (Fertility Issues)

    Medline Plus

    Full Text Available ... preservation needs of children? How do cancer and cancer treatment affect a child's fertility? Why should fertility preservation be a priority for my child? How does ovarian tissue cryopreservation differ for children ... What can a girl's cancer doctor do to protect her fertility? What can ...

  12. Air pollution and human fertility rates

    NARCIS (Netherlands)

    Nieuwenhuijsen, Mark J.; Basagaña, Xavier; Dadvand, Payam; Martinez, David; Cirach, Marta; Beelen, Rob; Jacquemin, Bénédicte

    2014-01-01

    Background: Some reports have suggested effects of air pollution on semen quality and success rates of in vitro fertilization (IVF) in humans and lower fertility rates in mice. However, no studies have evaluated the impact of air pollution on human fertility rates. Aims: We assessed the association

  13. Fertilization increases paddy soil organic carbon density

    Institute of Scientific and Technical Information of China (English)

    Shao-xian WANG; Xiao-jun LI; Xin-qiang LIANG; Qi-xiang LUO; Fang FAN; Ying-xu CHEN; Zu-zhang LI; Huo-xi SUN; Tian-fang DAI; Jun-nan WAN

    2012-01-01

    Field experiments provide an opportunity to study the effects of fertilization on soil organic carbon (SOC)sequestration.We sampled soils from a long-term (25 years) paddy experiment in subtropical China.The experiment included eight treatments:(1) check,(2) PK,(3) NP,(4) NK,(5) NPK,(6) 7F:3M (N,P,K inorganic fertilizers+30% organic N),(7) 5F:5M (N,P,K inorganic fertilizers+50% organic N),(8) 3F:7M (N,P,K inorganic fertilizers+70% organic N).Fertilization increased SOC content in the plow layers compared to the non-fertilized check treatment.The SOC density in the top 100 cm of soil ranged from 73.12 to 91.36 Mg/ha.The SOC densities of all fertilizer treatments were greater than that of the check.Those treatments that combined inorganic fertilizers and organic amendments had greater SOC densities than those receiving only inorganic fertilizers.The SOC density was closely correlated to the sum of the soil carbon converted from organic amendments and rice residues.Carbon sequestration in paddy soils could be achieved by balanced and combined fertilization.Fertilization combining both inorganic fertilizers and organic amendments is an effective sustainable practice to sequestrate SOC.

  14. Air pollution and human fertility rates

    NARCIS (Netherlands)

    Nieuwenhuijsen, Mark J.; Basagaña, Xavier; Dadvand, Payam; Martinez, David; Cirach, Marta; Beelen, Rob|info:eu-repo/dai/nl/30483100X; Jacquemin, Bénédicte

    2014-01-01

    Background: Some reports have suggested effects of air pollution on semen quality and success rates of in vitro fertilization (IVF) in humans and lower fertility rates in mice. However, no studies have evaluated the impact of air pollution on human fertility rates. Aims: We assessed the association

  15. [Fertility of black women: conjectures and questions].

    Science.gov (United States)

    Bercovich, A M

    1987-08-01

    Fertility change in Brazil is analyzed using data from censuses from 1940 to 1980 and the PNAD surveys of 1976 and 1984. Topics covered include regional fertility differentials, differences by ethnic group and color, and the impact of educational status on marital fertility. Consideration is given to methodological problems.

  16. Europe the continent with the lowest fertility

    NARCIS (Netherlands)

    Baird, D. T.; Collins, J.; Evers, J. L. H.; Leridon, H.; Lutz, W.; Velde, E. Te; Thevenon, O.; Crosignani, P. G.; Devroey, P.; Diedrich, K.; Fauser, B. C. J. M.; Fraser, L.; Geraedts, J. P. M.; Gianaroli, L.; Glasier, A.; Sunde, A.; Tarlatzis, B.; Van Steirteghem, A.; Veiga, A.

    2010-01-01

    INTRODUCTION: Although fertility rates are falling in many countries, Europe is the continent with the lowest total fertility rate (TFR). This review assesses trends in fertility rates, explores possible health and social factors and reviews the impact of health and social interventions designed to

  17. Fertilization increases paddy soil organic carbon density.

    Science.gov (United States)

    Wang, Shao-xian; Liang, Xin-qiang; Luo, Qi-xiang; Fan, Fang; Chen, Ying-xu; Li, Zu-zhang; Sun, Huo-xi; Dai, Tian-fang; Wan, Jun-nan; Li, Xiao-jun

    2012-04-01

    Field experiments provide an opportunity to study the effects of fertilization on soil organic carbon (SOC) sequestration. We sampled soils from a long-term (25 years) paddy experiment in subtropical China. The experiment included eight treatments: (1) check, (2) PK, (3) NP, (4) NK, (5) NPK, (6) 7F:3M (N, P, K inorganic fertilizers+30% organic N), (7) 5F:5M (N, P, K inorganic fertilizers+50% organic N), (8) 3F:7M (N, P, K inorganic fertilizers+70% organic N). Fertilization increased SOC content in the plow layers compared to the non-fertilized check treatment. The SOC density in the top 100 cm of soil ranged from 73.12 to 91.36 Mg/ha. The SOC densities of all fertilizer treatments were greater than that of the check. Those treatments that combined inorganic fertilizers and organic amendments had greater SOC densities than those receiving only inorganic fertilizers. The SOC density was closely correlated to the sum of the soil carbon converted from organic amendments and rice residues. Carbon sequestration in paddy soils could be achieved by balanced and combined fertilization. Fertilization combining both inorganic fertilizers and organic amendments is an effective sustainable practice to sequestrate SOC.

  18. Determinants of Fertility Differential in Korea.

    Science.gov (United States)

    Shin, Eui Hang; And Others

    1981-01-01

    Analyzes the causal relationships of the fertility differentials of 2200 married women in a small Korean town. Notes the effect on fertility of socioeconomic status, age at first marriage, family background, and various family planning strategies (contraception, abortion). Discusses a process model on fertility. (Author/SB)

  19. 7 CFR 2902.22 - Fertilizers.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 15 2010-01-01 2010-01-01 false Fertilizers. 2902.22 Section 2902.22 Agriculture... Fertilizers. (a) Definition. Products formulated or processed to provide nutrients for plant growth and/or beneficial bacteria to convert nutrients into plant usable forms. Biobased fertilizers, which are likely...

  20. Abortion Legalization and Life-Cycle Fertility

    Science.gov (United States)

    Ananat, Elizabeth Oltmans; Gruber, Jonathan; Levine, Phillip

    2007-01-01

    The early-1970s abortion legalization led to a significant drop in fertility. We investigate whether this decline represented a delay in births or a permanent reduction in fertility. We combine Census and Vital Statistics data to compare the lifetime fertility of women born in early-legalizing states, whose peak childbearing years occurred in the…

  1. Voluntary driven elbow orthosis with speed controlled tremor suppression

    Directory of Open Access Journals (Sweden)

    Gil eHerrnstadt

    2016-03-01

    Full Text Available Robotic technology is gradually becoming commonplace in the medical sector and in the service of patients. Medical conditions that have benefited from significant technological development include stroke, for which rehabilitation with robotic devices is administered, and surgery assisted by robots. Robotic devices have also been proposed for assistance of movement disorders. Pathological tremor, among the most common movement disorders, is such one example. In practice, the dissemination and availability of tremor suppression robotic systems has been limited. Devices in the marketplace tend to either be non-ambulatory or to target specific functions such as eating and drinking.We have developed a one degree-of-freedom (DOF elbow orthosis that could be worn by an individual with tremor. A speed controlled voluntary driven suppression approach is implemented with the orthosis. Typically tremor suppression methods estimate the tremor component of the signal and produce a canceling counterpart signal. The suggested approach, instead estimates the voluntary component of the motion. A controller then actuates the orthosis based on the voluntary signal while simultaneously rejecting the tremorous motion.In this work, we tested the suppressive orthosis using a 1 DOF robotic system that simulates the human arm. The suggested suppression approach does not require a model of the human arm. Moreover, the human input along with the orthosis forearm gravitational forces, of nonlinear nature, are considered as part of the disturbance to the suppression system. Therefore, the suppression system can be modeled linearly. Nevertheless, the orthosis forearm gravitational forces can be compensated by the suppression system.The electromechanical design of the orthosis is presented, and data from an Essential Tremor patient is used as the human input. Velocity tracking results demonstrate an RMS error of 0.31 rad/s, and a power spectral density shows a reduction of

  2. Multi-class EEG classification of voluntary hand movement directions

    Science.gov (United States)

    Robinson, Neethu; Guan, Cuntai; Vinod, A. P.; Keng Ang, Kai; Tee, Keng Peng

    2013-10-01

    Objective. Studies have shown that low frequency components of brain recordings provide information on voluntary hand movement directions. However, non-invasive techniques face more challenges compared to invasive techniques. Approach. This study presents a novel signal processing technique to extract features from non-invasive electroencephalography (EEG) recordings for classifying voluntary hand movement directions. The proposed technique comprises the regularized wavelet-common spatial pattern algorithm to extract the features, mutual information-based feature selection, and multi-class classification using the Fisher linear discriminant. EEG data from seven healthy human subjects were collected while they performed voluntary right hand center-out movement in four orthogonal directions. In this study, the movement direction dependent signal-to-noise ratio is used as a parameter to denote the effectiveness of each temporal frequency bin in the classification of movement directions. Main results. Significant (p movement direction dependent modulation in the EEG data was identified largely towards the end of movement at low frequencies (≤6 Hz) from the midline parietal and contralateral motor areas. Experimental results on single trial classification of the EEG data collected yielded an average accuracy of (80.24 ± 9.41)% in discriminating the four different directions using the proposed technique on features extracted from low frequency components. Significance. The proposed feature extraction strategy provides very high multi-class classification accuracies, and the results are proven to be more statistically significant than existing methods. The results obtained suggest the possibility of multi-directional movement classification from single-trial EEG recordings using the proposed technique in low frequency components.

  3. Forearm muscle oxygenation decreases with low levels of voluntary contraction

    Science.gov (United States)

    Murthy, G.; Kahan, N. J.; Hargens, A. R.; Rempel, D. M.

    1997-01-01

    The purpose of our investigation was to determine if the near infrared spectroscopy technique was sensitive to changes in tissue oxygenation at low levels of isometric contraction in the extensor carpi radialis brevis muscle. Nine subjects were seated with the right arm abducted to 45 degrees, elbow flexed to 85 degrees, forearm pronated 45 degrees, and wrist and forearm supported on an armrest throughout the protocol. Altered tissue oxygenation was measured noninvasively with near infrared spectroscopy. The near infrared spectroscopy probe was placed over the extensor carpi radialis brevis of the subject's right forearm and secured with an elastic wrap. After 1 minute of baseline measurements taken with the muscle relaxed, four different loads were applied just proximal to the metacarpophalangeal joint such that the subjects isometrically contracted the extensor carpi radialis brevis at 5, 10, 15, and 50% of the maximum voluntary contraction for 1 minute each. A 3-minute recovery period followed each level of contraction. At the end of the protocol, with the probe still in place, a value for ischemic tissue oxygenation was obtained for each subject. This value was considered the physiological zero and hence 0% tissue oxygenation. Mean tissue oxygenation (+/-SE) decreased from resting baseline (100% tissue oxygenation) to 89 +/- 4, 81 +/- 8, 78 +/- 8, and 47 +/- 8% at 5, 10, 15, and 50% of the maximum voluntary contraction, respectively. Tissue oxygenation levels at 10, 15, and 50% of the maximum voluntary contraction were significantly lower (p muscle contraction and that near infrared spectroscopy is a sensitive technique for detecting deoxygenation noninvasively at low levels of forearm muscle contraction. Our findings have important implications in occupational medicine because oxygen depletion induced by low levels of muscle contraction may be directly linked to muscle fatigue.

  4. THE VOLUNTARY HEALTH INSURANCE IN BULGARIA - HISTORY, DEVELOPMENT AND CHANGES

    OpenAIRE

    Natalia M. Shtereva-Nikolova; Nikolay A. Popov; Tsvetelina M. Petrova-Gotova

    2014-01-01

    The aim of this article is to show the history and development of the Voluntary Health Insurance (VHI) in Bulgaria and the recent regulatory changes. During the investigated period (2003–2012) the market increases over seven times, the number of working and licensed VHI funds grew over three times. The regulatory changes in 2013 require re-licensing and higher capital, which reduced the number of the VHI companies. We analyze the changes in the market and how VHI funds succeed to meet the inc...

  5. Benzyl alcohol increases voluntary ethanol drinking in rats.

    Science.gov (United States)

    Etelälahti, T J; Eriksson, C J P

    2014-09-01

    The anabolic steroid nandrolone decanoate has been reported to increase voluntary ethanol intake in Wistar rats. In recent experiments we received opposite results, with decreased voluntary ethanol intake in both high drinking AA and low drinking Wistar rats after nandrolone treatment. The difference between the two studies was that we used pure nandrolone decanoate in oil, whereas in the previous study the nandrolone product Deca-Durabolin containing benzyl alcohol (BA) was used. The aims of the present study were to clarify whether the BA treatment could promote ethanol drinking and to assess the role of the hypothalamic-pituitary-adrenal-gonadal axes (HPAGA) in the potential BA effect. Male AA and Wistar rats received subcutaneously BA or vehicle oil for 14 days. Hereafter followed a 1-week washout and consecutively a 3-week voluntary alcohol consumption period. The median (± median absolute deviation) voluntary ethanol consumption during the drinking period was higher in BA-treated than in control rats (4.94 ± 1.31 g/kg/day vs. 4.17 ± 0.31 g/kg/day, p = 0.07 and 1.01 ± 0.26 g/kg/day vs. 0.38 ± 0.27 g/kg/day, p = 0.05, for AA and Wistar rats, respectively; combined effect p < 0.01). The present results can explain the previous discrepancy between the two nandrolone studies. No significant BA effects on basal and ethanol-mediated serum testosterone and corticosterone levels were observed in blood samples taken at days 1, 8 and 22. However, 2h after ethanol administration significantly (p = 0.02) higher frequency of testosterone elevations was detected in high drinking AA rats compared to low drinking Wistars, which supports our previous hypotheses of a role of testosterone elevation in promoting ethanol drinking. Skin irritation and dermatitis were shown exclusively in the BA-treated animals. Altogether, the present results indicate that earlier findings obtained with Deca-Durabolin containing BA need to be re-evaluated.

  6. Ecological feedbacks can reduce population-level efficacy of wildlife fertility control

    Science.gov (United States)

    Ransom, Jason I.; Powers, Jenny G.; Hobbs, N. Thompson; Baker, Dan L.

    2014-01-01

    1. Anthropogenic stress on natural systems, particularly the fragmentation of landscapes and the extirpation of predators from food webs, has intensified the need to regulate abundance of wildlife populations with management. Controlling population growth using fertility control has been considered for almost four decades, but nearly all research has focused on understanding effects of fertility control agents on individual animals. Questions about the efficacy of fertility control as a way to control populations remain largely unanswered. 2. Collateral consequences of contraception can produce unexpected changes in birth rates, survival, immigration and emigration that may reduce the effectiveness of regulating animal abundance. The magnitude and frequency of such effects vary with species-specific social and reproductive systems, as well as connectivity of populations. Developing models that incorporate static demographic parameters from populations not controlled by contraception may bias predictions of fertility control efficacy. 3. Many population-level studies demonstrate that changes in survival and immigration induced by fertility control can compensate for the reduction in births caused by contraception. The most successful cases of regulating populations using fertility control come from applications of contraceptives to small, closed populations of gregarious and easily accessed species. 4. Fertility control can result in artificial selection pressures on the population and may lead to long-term unintentional genetic consequences. The magnitude of such selection is dependent on individual heritability and behavioural traits, as well as environmental variation. 5. Synthesis and applications. Understanding species' life-history strategies, biology, behavioural ecology and ecological context is critical to developing realistic expectations of regulating populations using fertility control. Before time, effort and funding are invested in wildlife

  7. ASK1 physically interacts with COI1 and is required for male fertility in Arabidopsis

    Institute of Scientific and Technical Information of China (English)

    戴良英; 徐领会; 黄大昉; 李栒; 罗宽; 官春云

    2002-01-01

    Jasmonates are a new class of plant hormones that play important roles in plant development and plant defense. The COI1 gene was previously shown to be required for jasmonate- regulated plant fertility and defense. We demonstrated for the first time that COI1 interacts with the Arabidopsis SKP1-LIKE1 (ASK1) to form a complex that is required for jasmonate action in planta. Functional analysis by antisense strategy showed that ASK1 is involved in male fertility.

  8. Fertilization-induced autophagy in mouse embryos is independent of mTORC1.

    Science.gov (United States)

    Yamamoto, Atsushi; Mizushima, Noboru; Tsukamoto, Satoshi

    2014-07-01

    Autophagy is a dynamically regulated intracellular degradation system that is important for cellular processes such as amino acid production during starvation and intracellular quality control. Previously, we reported that autophagy is suppressed in oocytes but is rapidly up-regulated after fertilization. During this period, autophagy is thought to be important for the generation of amino acids from the bulk degradation of maternal proteins that have accumulated during oogenesis. However, the mechanism of autophagy induction after fertilization is presently unknown. In most cell types, autophagy is negatively controlled by mammalian target of rapamycin complex 1 (mTORC1), which is typically regulated by amino acids and insulin or related growth factors. In this study, we determined the role of mTORC1 in fertilization-induced autophagy. On the basis of the phosphorylation status of mTORC1 substrates, we found that mTORC1 activity was relatively high in metaphase II (MII) oocytes but was rapidly decreased within 3 h of fertilization. However, chemical inhibition of mTORC1 by Torin1 or PP242 in MII oocytes or fertilized embryos did not induce autophagy. In addition, activation of mTORC1 by cycloheximide did not inhibit fertilization-induced autophagy in fertilized embryos. By contrast, the phosphatidylinositol 3-kinase inhibitors wortmannin and LY294002 effectively suppressed autophagy in these embryos. These data suggest that, even though autophagy induction and postfertilization mTORC1 activity are inversely correlated with each other, as observed in other cell types, mTORC1 suppression is neither essential nor sufficient for fertilization-induced autophagy, highlighting a unique feature of the regulation mechanism of autophagy-mediated intracellular turnover in early embryos. © 2014 by the Society for the Study of Reproduction, Inc.

  9. Time of day influences the voluntary intake and behavioral response to methamphetamine and food reward.

    Science.gov (United States)

    Keith, Diana R; Hart, Carl L; Robotham, Margaret; Tariq, Maliha; Le Sauter, Joseph; Silver, Rae

    2013-09-01

    The circadian timing system influences a vast array of behavioral responses. Substantial evidence indicates a role for the circadian system in regulating reward processing. Here we explore time of day effects on drug anticipation, locomotor activity, and voluntary methamphetamine (MA) and food intake in animals with ad libitum food access. We compared responses to drug versus a palatable treat during their normal sleep times in early day (zeitgeber time (ZT) 0400) or late day (ZT 1000). In the first study, using a between-subjects design, mice were given daily 1-h access to either peanut butter (PB-Alone) or to a low or high concentration of MA mixed in PB (MA+PB). In study 2, we repeated the experiment using a within-subjects design in which mice could choose between PB-Alone and MA+PB at either ZT 0400 or 1000. In study 3, the effects of MA-alone were investigated by evaluating anticipatory activity preceding exposure to nebulized MA at ZT 0400 vs. ZT 1000. Time of day effects were observed for both drug and palatable treat, such that in the between groups design, animals showed greater intake, anticipatory activity, and post-ingestional activity in the early day. Furthermore, there were differences among mice in the amount of MA ingested but individuals were self-consistent in their daily intake. The results for the within-subjects experiment also revealed robust individual differences in preference for MA+PB or PB-Alone. Interestingly, time of day effects on intake were observed only for the preferred substance. Anticipatory activity preceding administration of MA by nebulization was also greater at ZT 0400 than ZT 1000. Finally, pharmacokinetic response to MA administered intraperitoneally did not vary as a function of time of administration. The results indicate that time of day is an important variable mediating the voluntary intake and behavioral effects of reinforcers.

  10. PKA-regulated phosphorylation status of S149 and S321 sites of CDC25B inhibits mitosis of fertilized mouse eggs%蛋白激酶A对CDC25B蛋白S149与S321位点磷酸化的修饰抑制小鼠1-细胞期受精卵有丝分裂

    Institute of Scientific and Technical Information of China (English)

    肖建英; 刘超; 孙小涵; 于秉治

    2012-01-01

    To further test whether protein kinase A (PKA) can affect the mitotic cell cycle, one-cell stage mouse embryos at S phase (22 h after hCG injection) were incubated in M16 medium containing various concentrations of H-89, a PKA inhibitor. With increasing concentrations of H-89 (0-50 μmol/L), the G2 phase of eggs was decreased and the cleavage rate was accelerated. A concentration of 40 μmol/L H-89 led to all of the mouse eggs entering the M phase of mitosis. Furthermore, to study the role of PKA in regulating the phosphorylation status of S149 and S321 sites of cell division cycle 25B (CDC25B) on one-cell stage fertilized mouse eggs, pBSK-CDC25B-WT, pBSK-CDC25B-S149A, pBSK-CDC25B-S321A and pBSK-CDC25B-S149A/S321A were transcribed into mRNAs in vitro, then mRNAs were microinjected into S phase of mouse fertilized eggs and cultured in M16 medium pretreated with H-89. Then, the cleavage of fertilized eggs, maturation promoting factor (MPF) activity and phosphorylation status of CDC2-Tyr15 were observed. In the presence of 40 umol/L H-89, the cleavage rate of fertilized eggs in CDC25B-S/A-mRNAs and CDC25B-WT-mRNA injected groups was significantly higher than that in the control groups, and the peak of MPF activity appeared in the CDC25B-S/A-mRNAs and CDC25B-WT-mRNA injected groups earlier than that in the control groups. CDC2-Tyr15 phosphorylation state was consistent with MPF activity. In conclusion, the present study suggests that PKA regulates the early development ofmouse embryos by phosphorylation of S149 and S321 of CDC25B, which plays an important role in the regulation of G2/M transition in the mitotic cell cycle of fertilized mouse eggs.%在小鼠1-细胞期受精卵,蛋白激酶A (protein kinase A,PKA)可通过磷酸化细胞分裂周期25B (cell division cycle 25B,CDC25B)的321位Ser引起受精卵分裂阻滞.本文旨在研究PKA对CDC25B 149位点Ser的磷酸化对小鼠受精卵发育的影响,及其与321位点的关系.质粒pBSK-CDC25B-WT (

  11. Real-time changes in corticospinal excitability during voluntary contraction with concurrent electrical stimulation.

    Directory of Open Access Journals (Sweden)

    Tomofumi Yamaguchi

    Full Text Available While previous studies have assessed changes in corticospinal excitability following voluntary contraction coupled with electrical stimulation (ES, we sought to examine, for the first time in the field, real-time changes in corticospinal excitability. We monitored motor evoked potentials (MEPs elicited by transcranial magnetic stimulation and recorded the MEPs using a mechanomyogram, which is less susceptible to electrical artifacts. We assessed the MEPs at each level of muscle contraction of wrist flexion (0%, 5%, or 20% of maximum voluntary contraction during voluntary wrist flexion (flexor carpi radialis (FCR voluntary contraction, either with or without simultaneous low-frequency (10 Hz ES of the median nerve that innervates the FCR. The stimulus intensity corresponded to 1.2 × perception threshold. In the FCR, voluntary contraction with median nerve stimulation significantly increased corticospinal excitability compared with FCR voluntary contraction without median nerve stimulation (p<0.01. In addition, corticospinal excitability was significantly modulated by the level of FCR voluntary contraction. In contrast, in the extensor carpi radialis (ECR, FCR voluntary contraction with median nerve stimulation significantly decreased corticospinal excitability compared with FCR voluntary contraction without median nerve stimulation (p<0.05. Thus, median nerve stimulation during FCR voluntary contraction induces reciprocal changes in cortical excitability in agonist and antagonist muscles. Finally we also showed that even mental imagery of FCR voluntary contraction with median nerve stimulation induced the same reciprocal changes in cortical excitability in agonist and antagonist muscles. Our results support the use of voluntary contraction coupled with ES in neurorehabilitation therapy for patients.

  12. Effect of voluntary exercise on BDNF/TrkB gene expression and alcohol intake.

    OpenAIRE

    Jonsson, Josefine

    2012-01-01

    Voluntary wheel running is rewarding and believed to activate the same brain reward system as in alcohol and drug addiction. Brain-derived neurotrophic factor (BDNF), a well-known growth factor widely expressed in the brain, is modulated by both voluntary exercise and alcohol consumption. The aim of this study was to evaluate how voluntary exercise affects the expression levels of BDNF and its receptor TrkB in brain regions involved in positive and negative reinforcement. Additionally we want...

  13. Impact of Canada's Voluntary Agreement on Greenhouse Gas Emissions from Light Duty Vehicles

    OpenAIRE

    Lutsey, Nicholas P.

    2006-01-01

    On April 5, 2005, a voluntary agreement between the automobile industry and government officials of Canada was reached to commit to greenhouse gas emission reductions through the year 2010. This report compares Canada's voluntary agreement with other voluntary and mandatory greenhouse gas reduction programs around the world in terms of what technologies are likely to be deployed and how much vehicle fuel consumption is likely to improve. It investigates various methods and measurement approac...

  14. Maximal force, voluntary activation and muscle soreness after eccentric damage to human elbow flexor muscles

    Science.gov (United States)

    Prasartwuth, O; Taylor, JL; Gandevia, SC

    2005-01-01

    Muscle damage reduces voluntary force after eccentric exercise but impaired neural drive to the muscle may also contribute. To determine whether the delayed-onset muscle soreness, which develops ∼1 day after exercise, reduces voluntary activation and to identify the possible site for any reduction, voluntary activation of elbow flexor muscles was examined with both motor cortex and motor nerve stimulation. We measured maximal voluntary isometric torque (MVC), twitch torque, muscle soreness and voluntary activation in eight subjects before, immediately after, 2 h after, 1, 2, 4 and 8 days after eccentric exercise. Motor nerve stimulation and motor cortex stimulation were used to derive twitch torques and measures of voluntary activation. Eccentric exercise immediately reduced the MVC by 38 ± 3% (mean ±s.d., n = 8). The resting twitch produced by motor nerve stimulation fell by 82 ± 6%, and the estimated resting twitch by cortical stimulation fell by 47 ± 15%. While voluntary torque recovered after 8 days, both measures of the resting twitch remained depressed. Muscle tenderness occurred 1–2 days after exercise, and pain during contractions on days 1–4, but changes in voluntary activation did not follow this time course. Voluntary activation assessed with nerve stimulation fell 19 ± 6% immediately after exercise but was not different from control values after 2 days. Voluntary activation assessed by motor cortex stimulation was unchanged by eccentric exercise. During MVCs, absolute increments in torque evoked by nerve and cortical stimulation behaved differently. Those to cortical stimulation decreased whereas those to nerve stimulation tended to increase. These findings suggest that reduced voluntary activation contributes to the early force loss after eccentric exercise, but that it is not due to muscle soreness. The impairment of voluntary activation to nerve stimulation but not motor cortical stimulation suggests that the activation deficit lies in the

  15. A policy analysis of voluntary agreements for energy efficiency in industry

    Energy Technology Data Exchange (ETDEWEB)

    Larsen, Anders; Krarup, Signe; Kraemer, Trine Pipi [AKF, Inst. of Local Government Studies, Copenhagen (Denmark)

    1998-12-31

    To a growing degree voluntary agreements are used as an energy policy instrument in industrial energy policy in Europe. This paper investigates voluntary agreements of Great Britain, Denmark, Finland, the Netherlands and Sweden. The paper analyses the design and effects of these agreements and on this background discusses general implications of using voluntary agreements as a policy instrument in industrial energy policy. (au) EFP-95. 23 refs.

  16. [Regional difference of NPK fertilizers application and environmental risk assessment in Jiangsu Province, China].

    Science.gov (United States)

    Liu, Qin-pu

    2015-05-01

    It is of great importance to have a deep understanding of the spatial distribution of NPK fertilizers application and the potential threat to the ecological environment in Jiangsu Province, which is helpful for regulating the rational fertilization, strengthening the fertilizer use risk management and guidance, and preventing agricultural non-point pollution. Based on the environmental risk assessment model with consideration of different impacts of N, P, K fertilizers on environment, this paper researched the regional differentiation characteristic and environmental risk of intensity of NPK fertilizer usages in Jiangsu. Analystic hierarchy process ( AHP) was used to determine the weithts of N, P, K. The environmental safety thresholds of N, P, K were made according to the standard of 250 kg · hm(-2) for the construction of ecological counties sponsered by Chinese government and the proportion of 1:0.5:0.5 for N:P:K surposed by some developed countries. The results showed that the intensity of NPK fertilizer application currently presented a gradually increasing trend from south to north of Jiangsu, with the extremum ratio of 3.3, and the extremum ratios of nitrogen fertilizer, phosphorus fertilizer and potassium fertilizer were 3.3, 4.5 and 4.4, respectively. The average proportion of nitrogen fertilizer, phosphorus fertilizer and potassium fertilizer of 13 cities in Jiangsu was 1:0.39:0.26. Their proportion was relatively in equilibrium in southern Jiangsu, but the nutrient structure disorder was serious in northern Jiangsu. In Jiangsu, the environmental risk index of fertilization averaged at 0.69 and in the middle-range of environmental risk. The environmental risk index of fertilizer application in southern and central Jiangsu was respectively at the low and moderate levels, while that of cities in northern Jiangsu was at the moderate, serious or severe level. In Jiangsu, the regional difference of fertilizer application and environmental risk assessment were

  17. Fertility in female childhood cancer survivors

    DEFF Research Database (Denmark)

    De Bruin, Marie L; Van Dulmen-den Broeder, Eline; Van den Berg, Marleen H

    2009-01-01

    chemotherapy and radiotherapy may have an adverse effect on ovarian function, ovarian reserve and uterine function, clinically leading to sub-fertility, infertility, premature menopause and/or adverse pregnancy outcomes. Here we will first address normal female fertility and methods to detect decreased...... fertility. Hence we will focus on direct effects as well as late fertility-related adverse effects caused by chemotherapy and radiotherapy, and we will conclude with a summary of current options for fertility preservation in female childhood cancer survivors....

  18. Modelling and simulations of controlled release fertilizer

    Science.gov (United States)

    Irfan, Sayed Ameenuddin; Razali, Radzuan; Shaari, Ku Zilati Ku; Mansor, Nurlidia

    2016-11-01

    The recent advancement in controlled release fertilizer has provided an alternative solution to the conventional urea, controlled release fertilizer has a good plant nutrient uptake they are environment friendly. To have an optimum plant intake of nutrients from controlled release fertilizer it is very essential to understand the release characteristics. A mathematical model is developed to predict the release characteristics from polymer coated granule. Numerical simulations are performed by varying the parameters radius of granule, soil water content and soil porosity to study their effect on fertilizer release. Understanding these parameters helps in the better design and improve the efficiency of controlled release fertilizer.

  19. Voluntary activation of human knee extensors measured using transcranial magnetic stimulation.

    Science.gov (United States)

    Goodall, S; Romer, L M; Ross, E Z

    2009-09-01

    The aim of this study was to determine the applicability and reliability of a transcranial magnetic stimulation twitch interpolation technique for measuring voluntary activation of a lower limb muscle group. Cortical voluntary activation of the knee extensors was determined in nine healthy men on two separate visits by measuring superimposed twitch torques evoked by transcranial magnetic stimulation during isometric knee extensions of varying intensity. Superimposed twitch amplitude decreased linearly with increasing voluntary torque between 50 and 100% of mean maximal torque, allowing estimation of resting twitch amplitude and subsequent calculation of voluntary activation. There were no systematic differences for maximal voluntary activation within day (mean +/- s.d. 90.9 +/- 6.2 versus 90.7 +/- 5.9%; P = 0.98) or between days (90.8 +/- 6.0 versus 91.2 +/- 5.7%; P = 0.92). Systematic bias and random error components of the 95% limits of agreement were 0.23 and 9.3% within day versus 0.38 and 7.5% between days. Voluntary activation was also determined immediately after a 2 min maximal voluntary isometric contraction; in four of these subjects, voluntary activation was determined 30 min after the sustained contraction. Immediately after the sustained isometric contraction, maximal voluntary activation was reduced from 91.2 +/- 5.7 to 74.2 +/- 12.0% (P knee extensors.

  20. Is there a place for voluntary active euthanasia in modern-day medicine?

    National Research Council Canada - National Science Library

    Ogunbanjo, GA; Knapp van Bogaert, D

    2013-01-01

    This article discusses various ethical and legal concepts regarding euthanasia and includes notions such as physician-assisted suicide, assisted suicide, voluntary active euthanasia, killing versus...