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Sample records for volume work defining

  1. Multiplexed Dosing Assays by Digitally Definable Hydrogel Volumes

    DEFF Research Database (Denmark)

    Faralli, Adele; Melander, Fredrik; Larsen, Esben Kjær Unmack

    2016-01-01

    Stable and low-cost multiplexed drug sensitivity assays using small volumes of cells or tissue are in demand for personalized medicine, including patientspecific combination chemotherapy. Spatially defined projected light photopolymerization of hydrogels with embedded active compounds is introduc...

  2. Defining characteristics of the nursing diagnosis: excess fluid volume.

    OpenAIRE

    Narriman Silva De Oliveira Boery, Rita; Bottura Leite De Barros, Alba Lúcia; de Fátima Lucena, Amália

    2008-01-01

    A descriptive exploratory study about the defining characteristics of the nursing diagnosis: excess fluid volume, founde by the North American Nursing Diagnosis Association – NANDA. Carried out in an institution in São Paulo, SP, it aimed at the detection of the usage and significance assigned to the defining characteristics, as well as the skills associated to the propaedeutic procedures used in nursing clinical practice to determine such diagnosis. Data were collected through a questionnair...

  3. MITA Working Papers in Psycholinguistics, Volume 3.

    Science.gov (United States)

    Otsu, Yukio, Ed.

    1993-01-01

    This volume of working papers in psycholinguistics, from the "MITA Psycholinguistics Circle", contains the following articles: "Some Problems in the Acquisition of Derived Nouns" (Mika Endo); "World Knowledge in Children's Sentence Comprehension" (Yuki Hirose); "Examining the Including and Excluding Roles of Positive Evidence: A Study of a Case…

  4. Variance in brain volume with advancing age: implications for defining the limits of normality.

    Directory of Open Access Journals (Sweden)

    David Alexander Dickie

    Full Text Available Statistical models of normal ageing brain tissue volumes may support earlier diagnosis of increasingly common, yet still fatal, neurodegenerative diseases. For example, the statistically defined distribution of normal ageing brain tissue volumes may be used as a reference to assess patient volumes. To date, such models were often derived from mean values which were assumed to represent the distributions and boundaries, i.e. percentile ranks, of brain tissue volume. Since it was previously unknown, the objective of the present study was to determine if this assumption was robust, i.e. whether regression models derived from mean values accurately represented the distributions and boundaries of brain tissue volume at older ages.We acquired T1-w magnetic resonance (MR brain images of 227 normal and 219 Alzheimer's disease (AD subjects (aged 55-89 years from publicly available databanks. Using nonlinear regression within both samples, we compared mean and percentile rank estimates of whole brain tissue volume by age.In both the normal and AD sample, mean regression estimates of brain tissue volume often did not accurately represent percentile rank estimates (errors=-74% to 75%. In the normal sample, mean estimates generally underestimated differences in brain volume at percentile ranks below the mean. Conversely, in the AD sample, mean estimates generally underestimated differences in brain volume at percentile ranks above the mean. Differences between ages at the 5(th percentile rank of normal subjects were ~39% greater than mean differences in the AD subjects.While more data are required to make true population inferences, our results indicate that mean regression estimates may not accurately represent the distributions of ageing brain tissue volumes. This suggests that percentile rank estimates will be required to robustly define the limits of brain tissue volume in normal ageing and neurodegenerative disease.

  5. Diagnostic accuracy of the defining characteristics of the excessive fluid volume diagnosis in hemodialysis patients

    Directory of Open Access Journals (Sweden)

    Maria Isabel da Conceição Dias Fernandes

    2015-12-01

    Full Text Available Objective: to evaluate the accuracy of the defining characteristics of the excess fluid volume nursing diagnosis of NANDA International, in patients undergoing hemodialysis. Method: this was a study of diagnostic accuracy, with a cross-sectional design, performed in two stages. The first, involving 100 patients from a dialysis clinic and a university hospital in northeastern Brazil, investigated the presence and absence of the defining characteristics of excess fluid volume. In the second step, these characteristics were evaluated by diagnostic nurses, who judged the presence or absence of the diagnosis. To analyze the measures of accuracy, sensitivity, specificity, and positive and negative predictive values were calculated. Approval was given by the Research Ethics Committee under authorization No. 148.428. Results: the most sensitive indicator was edema and most specific were pulmonary congestion, adventitious breath sounds and restlessness. Conclusion: the more accurate defining characteristics, considered valid for the diagnostic inference of excess fluid volume in patients undergoing hemodialysis were edema, pulmonary congestion, adventitious breath sounds and restlessness. Thus, in the presence of these, the nurse may safely assume the presence of the diagnosis studied.

  6. Defining the public, defining sociology: hybrid science-public relations and boundary-work in early American sociology.

    Science.gov (United States)

    Evans, Michael S

    2009-01-01

    In this paper, I examine how scientific disciplines define their boundaries by defining the publics with whom they engage. The case study is an episode in the development of early American sociology. In response to the dual challenge of credibility set up by the conflict between religious Baconian science and secular positivist science, key actors engaged in specific strategies of boundary-work to create their desired "sociological public"--a hybrid form of science-public relations that appealed to hostile university scientists while excluding a supportive religious audience from participation in the production of scientific knowledge. Using this case, I offer two specific insights. First I illustrate how, in the pursuit of scientific credibility, actors engage in boundary-work to differentiate audiences, not just practitioners. Such defining of publics is constitutive of scientific disciplines in their formative stage. Second, I demonstrate how audience boundaries can be redefined through the capture of existing boundary objects. Specifically, the removal of informational content in key boundary objects creates durable boundaries that are difficult to overcome.

  7. Preterm Infant Hippocampal Volumes Correlate with Later Working Memory Deficits

    Science.gov (United States)

    Beauchamp, Miriam H.; Thompson, Deanne K.; Howard, Kelly; Doyle, Lex W.; Egan, Gary F.; Inder, Terrie E.; Anderson, Peter J.

    2008-01-01

    Children born preterm exhibit working memory deficits. These deficits may be associated with structural brain changes observed in the neonatal period. In this study, the relationship between neonatal regional brain volumes and working memory deficits at age 2 years were investigated, with a particular interest in the dorsolateral prefrontal…

  8. Preterm Infant Hippocampal Volumes Correlate with Later Working Memory Deficits

    Science.gov (United States)

    Beauchamp, Miriam H.; Thompson, Deanne K.; Howard, Kelly; Doyle, Lex W.; Egan, Gary F.; Inder, Terrie E.; Anderson, Peter J.

    2008-01-01

    Children born preterm exhibit working memory deficits. These deficits may be associated with structural brain changes observed in the neonatal period. In this study, the relationship between neonatal regional brain volumes and working memory deficits at age 2 years were investigated, with a particular interest in the dorsolateral prefrontal…

  9. Considerations of circadian impact for defining 'shift work' in cancer studies: IARC Working Group Report

    NARCIS (Netherlands)

    R.G. Stevens; J. Hansen; G. Costa; E. Haus; T. Kauppinen; K.J. Aronson; G. Castaño-Vinyals; S. Davis; M.H.W. Frings-Dresen; L. Fritschi; M. Kogevinas; K. Kogi; J.A. Lie; A. Lowden; B. Peplonska; B. Pesch; E. Pukkala; E. Schernhammer; R.C. Travis; R. Vermeulen; T. Zheng; V. Cogliano; K. Straif

    2011-01-01

    Based on the idea that electric light at night might account for a portion of the high and rising risk of breast cancer worldwide, it was predicted long ago that women working a non-day shift would be at higher risk compared with day-working women. This hypothesis has been extended more recently to

  10. Considerations of circadian impact for defining 'shift work' in cancer studies: IARC Working Group Report.

    Science.gov (United States)

    Stevens, Richard G; Hansen, Johnni; Costa, Giovanni; Haus, Erhard; Kauppinen, Timo; Aronson, Kristan J; Castaño-Vinyals, Gemma; Davis, Scott; Frings-Dresen, Monique H W; Fritschi, Lin; Kogevinas, Manolis; Kogi, Kazutaka; Lie, Jenny-Anne; Lowden, Arne; Peplonska, Beata; Pesch, Beate; Pukkala, Eero; Schernhammer, Eva; Travis, Ruth C; Vermeulen, Roel; Zheng, Tongzhang; Cogliano, Vincent; Straif, Kurt

    2011-02-01

    Based on the idea that electric light at night might account for a portion of the high and rising risk of breast cancer worldwide, it was predicted long ago that women working a non-day shift would be at higher risk compared with day-working women. This hypothesis has been extended more recently to prostate cancer. On the basis of limited human evidence and sufficient evidence in experimental animals, in 2007 the International Agency for Research on Cancer (IARC) classified 'shift work that involves circadian disruption' as a probable human carcinogen, group 2A. A limitation of the epidemiological studies carried out to date is in the definition of 'shift work.' IARC convened a workshop in April 2009 to consider how 'shift work' should be assessed and what domains of occupational history need to be quantified for more valid studies of shift work and cancer in the future. The working group identified several major domains of non-day shifts and shift schedules that should be captured in future studies: (1) shift system (start time of shift, number of hours per day, rotating or permanent, speed and direction of a rotating system, regular or irregular); (2) years on a particular non-day shift schedule (and cumulative exposure to the shift system over the subject's working life); and (3) shift intensity (time off between successive work days on the shift schedule). The group also recognised that for further domains to be identified, more research needs to be conducted on the impact of various shift schedules and routines on physiological and circadian rhythms of workers in real-world environments.

  11. University of New Mexico Working Papers in Linguistics, Volume 1.

    Science.gov (United States)

    Meehan, Teresa M., Ed.; Schwenter, Scott A., Ed.

    This volume contains working papers on a variety of topics in linguistics. They include: "A View of Phonology from a Cognitive and Functional Perspective" (Joan Bybee); "The Geography of Language Shift: Distance from the Mexican Border and Spanish Language Claiming in the Southwestern United States" (Garland D. Bills, Eduardo Hernandez-Chavez,…

  12. INSULIN-SECRETION BY RAT ISLET ISOGRAFTS OF A DEFINED ENDOCRINE VOLUME AFTER TRANSPLANTATION TO 3 DIFFERENT SITES

    NARCIS (Netherlands)

    VANSUYLICHEM, PTR; STRUBBE, JH; HOUWING, H; WOLTERS, GHJ; VANSCHILFGAARDE, R

    1992-01-01

    We have analysed the graft function of rat islet isografts of identical and well-defined endocrine volumes after transplantation to three different sites (kidney, liver and spleen). Graft endocrine mass was determined by measuring the total islet volume prior to transplantation and was chosen to be

  13. Insulin secretion by rat islet isografts of a defined endocrine volume after transplantation to three different sites

    NARCIS (Netherlands)

    Suylichem, P.T.R. van; Strubbe, J.H.; Houwing, H.; Wolters, G.H.J.; Schilfgaarde, R. van

    1992-01-01

    We have analysed the graft function of rat islet isografts of identical and well-defined endocrine volumes after transplantation to three different sites (kidney, liver and spleen). Graft endocrine mass was determined by measuring the total islet volume prior to transplantation and was chosen to be

  14. Work plan for defining a standard inventory estimate for wastes stored in Hanford site underground tanks

    Energy Technology Data Exchange (ETDEWEB)

    Kupfer, M.J.

    1995-09-29

    This work plan addresses the methodology for defining a tank waste database that will provide a best basis estimate of waste characteristics for each underground storage tank. The resulting database is expected to be in place in a network accessible electronic form by September 1996.

  15. Defining an evidence-based work environment for nursing in the USA.

    Science.gov (United States)

    Kotzer, Anne Marie; Arellana, Kerry

    2008-06-01

    To describe and compare staff nurses' perceptions of their real and ideal work environment in a tertiary paediatric facility; to provide administrators with research evidence for identifying areas for improvement. The workforce shortage of hospital nurses is a global problem having an impact on the financial resources and efficient operations of an organisation and the quality of care delivered to patients. A direct relationship exists between job satisfaction, retention, turnover and elements of the nurses' work environment. Research identifying specific elements of the current work setting that are in conflict with nurses' views of their preferred practice milieu can help define an evidence-based work environment for nursing. Using a descriptive survey design, a convenience sample of 385 nurses on five inpatient units and the float team completed two forms (real and ideal) of the work environment scale. The work environment scale consists of 10 subscales within three dimensions: relationship, personal growth and system maintenance and change. A consistent pattern was seen across all units with reported high levels of involvement, peer cohesion, task orientation and managerial control. Scores for work pressure and autonomy were moderate-high and physical comfort, supervisor support, clarity and innovation were moderate. Overall, highest scores were reported for involvement and lowest for physical comfort. Significant differences were found between real and ideal subscale scores suggesting that staff were able to identify areas for improvement. Despite moderate work pressure, staff affirmed a highly positive work environment on their units. Specific areas in their current work setting that were not congruent with their preferred work environment were identified and targeted for change. Understanding dimensions of the nurses' work environment needing improvement and involving staff in making and evaluating change supports an evidence-based environment to attract and

  16. Critical elements in defining work-based identity in a post-apartheid South Africa

    Directory of Open Access Journals (Sweden)

    Sandra Lloyd

    2011-03-01

    Full Text Available Orientation: The main focus of the study was to answer the question: ‘Who am I at work?’ in a post-apartheid South African organisation.Research purpose: The aim of the specific research questions was to determine which life sphere and life role elements, and which work-based identity facets were significant in forming work-based identity.Motivation for the study: The findings of the study will enable the formulation of an integrative definition of work-based identity applicable to the South African context.Research design, approach and method: Qualitative data was collected by means of unstructured interviews with 29 employees representing a range of job titles, levels and demographics in a large South African manufacturing company. A grounded theory approach (open and axial coding was used to analyse the data.Main findings: Distinctive individual self-definitions and a number of common themes integrating social and personal identity perspectives emerged from the data. These themes provided a sound basis for the proposed integrative model to define work-based identity.Practical/managerial implications: The findings of this research will assist human resource practitioners to develop training interventions and management strategies for the potential enhancement of work-based identities. This will result in a more engaged and harmonised workforce.Contribution/value-add: This was the first study of its kind to identify and delineate significant work-based identity elements for the formation of a work-based identity within a South African work context.

  17. Chemical Safety Vulnerability Working Group report. Volume 1

    Energy Technology Data Exchange (ETDEWEB)

    1994-09-01

    The Chemical Safety Vulnerability (CSV) Working Group was established to identify adverse conditions involving hazardous chemicals at DOE facilities that might result in fires or explosions, release of hazardous chemicals to the environment, or exposure of workers or the public to chemicals. A CSV Review was conducted in 148 facilities at 29 sites. Eight generic vulnerabilities were documented related to: abandoned chemicals and chemical residuals; past chemical spills and ground releases; characterization of legacy chemicals and wastes; disposition of legacy chemicals; storage facilities and conditions; condition of facilities and support systems; unanalyzed and unaddressed hazards; and inventory control and tracking. Weaknesses in five programmatic areas were also identified related to: management commitment and planning; chemical safety management programs; aging facilities that continue to operate; nonoperating facilities awaiting deactivation; and resource allocations. Volume 1 contains the Executive summary; Introduction; Summary of vulnerabilities; Management systems weaknesses; Commendable practices; Summary of management response plan; Conclusions; and a Glossary of chemical terms.

  18. Normovolemia defined according to cardiac stroke volume in healthy supine humans

    DEFF Research Database (Denmark)

    Bundgaard-Nielsen, Morten; Jørgensen, Christoffer C; Kehlet, Henrik

    2010-01-01

    BACKGROUND: Both hypovolemia and a fluid overload are detrimental for outcome in surgical patients but the effort to establish normovolemia is hampered by the lack of an operational clinical definition. Manipulating the central blood volume on a tilt table demonstrates that the flat part...

  19. Chemical Safety Vulnerability Working Group report. Volume 3

    Energy Technology Data Exchange (ETDEWEB)

    1994-09-01

    The Chemical Safety Vulnerability (CSV) Working Group was established to identify adverse conditions involving hazardous chemicals at DOE facilities that might result in fires or explosions, release of hazardous chemicals to the environment, or exposure of workers or the public to chemicals. A CSV Review was conducted in 148 facilities at 29 sites. Eight generic vulnerabilities were documented related to: abandoned chemicals and chemical residuals; past chemical spills and ground releases; characterization of legacy chemicals and wastes; disposition of legacy chemicals; storage facilities and conditions; condition of facilities and support systems; unanalyzed and unaddressed hazards; and inventory control and tracking. Weaknesses in five programmatic areas were also identified related to: management commitment and planning; chemical safety management programs; aging facilities that continue to operate; nonoperating facilities awaiting deactivation; and resource allocations. Volume 3 consists of eleven appendices containing the following: Field verification reports for Idaho National Engineering Lab., Rocky Flats Plant, Brookhaven National Lab., Los Alamos National Lab., and Sandia National Laboratories (NM); Mini-visits to small DOE sites; Working Group meeting, June 7--8, 1994; Commendable practices; Related chemical safety initiatives at DOE; Regulatory framework and industry initiatives related to chemical safety; and Chemical inventory data from field self-evaluation reports.

  20. Chemical Safety Vulnerability Working Group report. Volume 2

    Energy Technology Data Exchange (ETDEWEB)

    1994-09-01

    The Chemical Safety Vulnerability (CSV) Working Group was established to identify adverse conditions involving hazardous chemicals at DOE facilities that might result in fires or explosions, release of hazardous chemicals to the environment, or exposure of workers or the public to chemicals. A CSV Review was conducted in 148 facilities at 29 sites. Eight generic vulnerabilities were documented related to: abandoned chemicals and chemical residuals; past chemical spills and ground releases; characterization of legacy chemicals and wastes; disposition of legacy chemicals; storage facilities and conditions; condition of facilities and support systems; unanalyzed and unaddressed hazards; and inventory control and tracking. Weaknesses in five programmatic areas were also identified related to: management commitment and planning; chemical safety management programs; aging facilities that continue to operate; nonoperating facilities awaiting deactivation; and resource allocations. Volume 2 consists of seven appendices containing the following: Tasking memorandums; Project plan for the CSV Review; Field verification guide for the CSV Review; Field verification report, Lawrence Livermore National Lab.; Field verification report, Oak Ridge Reservation; Field verification report, Savannah River Site; and the Field verification report, Hanford Site.

  1. Gas permeation measurement under defined humidity via constant volume/variable pressure method

    KAUST Repository

    Jan Roman, Pauls

    2012-02-01

    Many industrial gas separations in which membrane processes are feasible entail high water vapour contents, as in CO 2-separation from flue gas in carbon capture and storage (CCS), or in biogas/natural gas processing. Studying the effect of water vapour on gas permeability through polymeric membranes is essential for materials design and optimization of these membrane applications. In particular, for amine-based CO 2 selective facilitated transport membranes, water vapour is necessary for carrier-complex formation (Matsuyama et al., 1996; Deng and Hägg, 2010; Liu et al., 2008; Shishatskiy et al., 2010) [1-4]. But also conventional polymeric membrane materials can vary their permeation behaviour due to water-induced swelling (Potreck, 2009) [5]. Here we describe a simple approach to gas permeability measurement in the presence of water vapour, in the form of a modified constant volume/variable pressure method (pressure increase method). © 2011 Elsevier B.V.

  2. Anatomic guidelines defined by reformatting images on MRI for volume measurement of amygdala and hippocampus

    Energy Technology Data Exchange (ETDEWEB)

    Hoshida, Tohru; Sakaki, Toshisuke [Nara Medical Univ., Kashihara (Japan); Uematsu, Sumio

    1995-03-01

    Twelve patients with intractable partial epilepsy underwent MR scans at the Epilepsy Center of the Johns Hopkins Hospital. There were five women and seven men, ranging in age from five to 51 years (mean age: 26 years). Coronal images were obtained using a 3-D SPGR. The coronal images were transferred to an Allegro 5.1 workstation, and reformatted along the cardinal axes (axial and sagittal) in multiple view points. The anterior end of the amygdala was measured at the level just posterior to the disappearance of the temporal stem. The semilunar gyrus of the amygdala was separated from the ambient gyrus by the semianular sulcus that forms the boundary between the amygdala and the entorhinal cortex. The delineation of the hippocampal formation included the subicular complex, hippocampal proper, dentate gyrus, alveus, and fimbria. The uncal cleft separated the uncus above from the parahippocampal gyrus below. The roof of this cleft was formed by the hippocampus and the dentate gyrus, and the floor, by the presubiculum and subiculum. Although using some guidelines, strictly separating the hippocampal head from the posterior part of the amygdala was not feasible as was previously reported, because of the isointensity on MRI between the cortex of the amygdala and the hippocampus. The most posterior portion of the hippocampus was measured at the level of the subsplenial gyri, just below the splenium of the corpus callosum, to measure the hippocampal volume in its near totality. Therefore, it is reliable, and clinically useful, to measure the combined total volume of the amygdala and the hippocampus when comparing results with those of other centers. (S.Y.).

  3. Defining Signature Pedagogy in Social Work Education: Learning Theory and the Learning Contract

    Science.gov (United States)

    Boitel, Craig R.; Fromm, Laurentine R.

    2014-01-01

    In 2008 the Council on Social Work Education identified field education as the signature pedagogy of social work. In doing so, it designated field education as the synthetic, integrative curricular area in which students are socialized to the profession. This article examines challenges and opportunities this designation presents. How field…

  4. No Correlation Between Work-Hours and Operative Volumes

    DEFF Research Database (Denmark)

    Kjærgaard, Jane; Sillesen, Martin; Beier-Holgersen, Randi

    2016-01-01

    OBJECTIVE: Since 2003, United States residents have been limited to an 80-hour workweek. This has prompted concerns of reduced educational quality, especially inadequate operating exposure. In contrast, the Danish surgical specialty-training program mandates a cap on working hours of 37 per week....

  5. Working to define data curated geospatial services on a Research Campus, a Purdue University Libraries Example

    Science.gov (United States)

    Branch, B. D.; Kong, N.; Fosmire, M.; Rousi, A. M.

    2013-12-01

    As Data Curation is becoming a necessity of data science and library science, Purdue University Libraries has been a leader in data curation profiles research. Such research can be defined as a data stewardship protocol similar to a multiple use case analysis. In this this example, The Purdue University Libraries Geographical Information Systems (GIS) department has engaged in a data curation profiles assessment of the campus to baseline and qualify sustainable geospatial data services. It is the intent that other libraries will consider this IRB approved approach of grounded theory to assessment the geospatial data service capacity and potential on a parametric scale. Provided is the status of such research and the some highlights or considerations in the establishment of sustainable geospatial data services that include a full data curated lifecycle. Noted here are some of the essential engagement endeavors of the research.

  6. Clinical usefulness of the definitions for defining characteristics of activity intolerance, excess fluid volume and decreased cardiac output in decompensated heart failure: a descriptive exploratory study.

    Science.gov (United States)

    de Souza, Vanessa; Zeitoun, Sandra Salloum; Lopes, Camila Takao; de Oliveira, Ana Paula Dias; Lopes, Juliana de Lima; de Barros, Alba Lucia Bottura Leite

    2015-09-01

    To assess the clinical usefulness of the operational definitions for the defining characteristics of the NANDA International nursing diagnoses, activity intolerance, decreased cardiac output and excess fluid volume, and the concomitant presence of those diagnoses in patients with decompensated heart failure. Content validity of the operational definitions for the defining characteristics of activity intolerance, excess fluid volume and decreased cardiac output have been previously validated by experts. Their clinical usefulness requires clinical validation. This was a descriptive exploratory study. Two expert nurses independently assessed 25 patients with decompensated heart failure for the presence or absence of 29 defining characteristics. Interrater reliability was analysed using the Kappa coefficient as a measure of clinical usefulness. The Fisher's exact test was used to test the association of the defining characteristics of activity intolerance and excess fluid volume in the presence of decreased cardiac output, and the correlation between the three diagnoses. Assessments regarding the presence of all defining characteristics reached 100% agreement, except with anxiety. Five defining characteristics of excess fluid volume were significantly associated with the presence of decreased cardiac output. Concomitant presence of the three diagnoses occurred in 80% of the patients. However, there was no significant correlation between the three diagnoses. The operational definitions for the diagnoses had strong interrater reliability, therefore they were considered clinically useful. Only five defining characteristics were representative of the association between excess fluid volume and decreased cardiac output. Therefore, excess fluid volume is related to decreased cardiac output, although these diagnoses are not necessarily associated with activity intolerance. The operational definitions may favour early recognition of the sequence of responses to decompensation

  7. The Application of Work Domain Analysis to Defining Australia’s Air Combat Capability

    Science.gov (United States)

    2014-03-01

    have the potential to further support the defence of Australia into the 2030- 2050 timeframe, whilst enhancing overall cost effectiveness. A work...encapsulated by use of the word protect. Australia: Definition:  “The continent South-East of Asia, lying between the Indian and Pacific Oceans ...sprains, dislocations, concussions, compressions, extremes of temperature or prolonged exposure, or exposure to toxic or poisonous substances

  8. Defining elements of sustainable work systems--a system-oriented approach.

    Science.gov (United States)

    Fischer, Klaus; Zink, Klaus J

    2012-01-01

    Based on a system-theoretic discussion of sustainability, this paper aims to develop a conceptual model of a sustainable work system which is consistent with the definition of ergonomics by the IEA in 2000 (but also with earlier definitions) as well as with the triple bottom line understanding of sustainable development - comprising the management of human, social, ecological and economic capital in a balanced manner.

  9. Defining the Optimal Planning Target Volume in Image-Guided Stereotactic Radiosurgery of Brain Metastases: Results of a Randomized Trial

    Energy Technology Data Exchange (ETDEWEB)

    Kirkpatrick, John P., E-mail: john.kirkpatrick@dm.duke.edu [Department of Radiation Oncology, Duke University, Durham, North Carolina (United States); Department of Surgery, Duke University, Durham, North Carolina (United States); Wang, Zhiheng [Department of Radiation Oncology, Duke University, Durham, North Carolina (United States); Sampson, John H. [Department of Radiation Oncology, Duke University, Durham, North Carolina (United States); Department of Surgery, Duke University, Durham, North Carolina (United States); McSherry, Frances; Herndon, James E. [Department of Biostatistics and Bioinformatics, Duke University, Durham, North Carolina (United States); Allen, Karen J.; Duffy, Eileen [Department of Radiation Oncology, Duke University, Durham, North Carolina (United States); Hoang, Jenny K. [Department of Radiology, Duke University, Durham, North Carolina (United States); Chang, Zheng; Yoo, David S.; Kelsey, Chris R.; Yin, Fang-Fang [Department of Radiation Oncology, Duke University, Durham, North Carolina (United States)

    2015-01-01

    Purpose: To identify an optimal margin about the gross target volume (GTV) for stereotactic radiosurgery (SRS) of brain metastases, minimizing toxicity and local recurrence. Methods and Materials: Adult patients with 1 to 3 brain metastases less than 4 cm in greatest dimension, no previous brain radiation therapy, and Karnofsky performance status (KPS) above 70 were eligible for this institutional review board–approved trial. Individual lesions were randomized to 1- or 3- mm uniform expansion of the GTV defined on contrast-enhanced magnetic resonance imaging (MRI). The resulting planning target volume (PTV) was treated to 24, 18, or 15 Gy marginal dose for maximum PTV diameters less than 2, 2 to 2.9, and 3 to 3.9 cm, respectively, using a linear accelerator–based image-guided system. The primary endpoint was local recurrence (LR). Secondary endpoints included neurocognition Mini-Mental State Examination, Trail Making Test Parts A and B, quality of life (Functional Assessment of Cancer Therapy-Brain), radionecrosis (RN), need for salvage radiation therapy, distant failure (DF) in the brain, and overall survival (OS). Results: Between February 2010 and November 2012, 49 patients with 80 brain metastases were treated. The median age was 61 years, the median KPS was 90, and the predominant histologies were non–small cell lung cancer (25 patients) and melanoma (8). Fifty-five, 19, and 6 lesions were treated to 24, 18, and 15 Gy, respectively. The PTV/GTV ratio, volume receiving 12 Gy or more, and minimum dose to PTV were significantly higher in the 3-mm group (all P<.01), and GTV was similar (P=.76). At a median follow-up time of 32.2 months, 11 patients were alive, with median OS 10.6 months. LR was observed in only 3 lesions (2 in the 1 mm group, P=.51), with 6.7% LR 12 months after SRS. Biopsy-proven RN alone was observed in 6 lesions (5 in the 3-mm group, P=.10). The 12-month DF rate was 45.7%. Three months after SRS, no significant change in

  10. Semiautomatic technique for defining the internal gross tumor volume of lung tumors close to liver/spleen cupola by 4D-CT

    Energy Technology Data Exchange (ETDEWEB)

    Mancosu, Pietro; Sghedoni, Roberto; Bettinardi, Valentino; Aquilina, Mark Anthony; Navarria, Piera; Cattaneo, Giovanni Mauro; Di Muzio, Nadia; Cozzi, Luca; Scorsetti, Marta [Department of Radiotherapy, IRCCS Istituto Clinico Humanitas, Rozzano, 20089 Milano (Italy); Department of Medical Physics, Arcispedale S. Maria Nuova, Reggio, 42100 Emilia (Italy); Department of Nuclear Medicine, Scientific Institute H. S. Raffaele, 20089 Milan (Italy); Department of Radiotherapy, IRCCS Istituto Clinico Humanitas, 20089 Rozzano, Milano (Italy); Department of Medical Physics, San Raffaele Scientific Institute, 20133 Milan (Italy); Department of Radiotherapy, San Raffaele Scientific Institute, 20133 Milan (Italy); Medical Physics Unit, Oncology Institute of Southern Switzerland, 6504 Bellinzona (Switzerland); Department of Radiotherapy, IRCCS Istituto Clinico Humanitas, 20089 Rozzano, Milano (Italy)

    2010-09-15

    Purpose: It has been shown that in cases of lung tumors close to the liver cupola, the four dimensional (4D)-CT postprocessing maximum intensity projection (MIP) algorithm does not fully recover the radiotherapy internal gross tumor volume (IGTV). In this work, a semiautomatic technique was evaluated by which the residual IGTV that was not included into the IGTV by MIP algorithm was actually added. Methods: A moving phantom and five selected patients were considered. The various IGTVs produced by the semiautomatic approach were compared to those generated by 4D-CT manual contouring. Results: In all cases, the radiation oncologist qualitatively concurred with the semiautomatic IGTV. A quantitative difference in volume of 2.6% was found in the phantom study, whereas a mean difference of 0.1{+-}4.6% was obtained in the patient studies. Conclusions: A semiautomatic technique to include the residual part of IGTV covered by liver/spleen cupola when using MIP algorithm was validated on phantom and on selected patients, revealing the possibility of defining the IGTV for patients with lesions located near liver/spleen cupola by performing only the contours on the MIP series.

  11. Modified pause schemes and working days for more volume flexibility in manufactering

    NARCIS (Netherlands)

    Rhijn, G.; Looze, M. de; Bosch, T.

    2005-01-01

    The effects of two measures to increase the volume flexibility, namely the introduction of an alternating pause scheme and the elongation of the working day, were evaluated in two manufacturing companies. Both measures led to an increase in volume output of about 16% at relatively low costs. The

  12. Coyote Papers: Working Papers in Linguistics from A-Z, Volume 10.

    Science.gov (United States)

    Fountain, Amy, Ed.; Hendricks, Sean, Ed.; Ohno, Sachiko, Ed.; Miyashita, Mizuki, Ed.; Cole, Debbie, Ed.

    The papers in this volume are all phonological in nature, and all but one of them are written within the framework of Optmality Theory. This volume includes work on a variety of languages: American Indian (Kiowa, Koasati, Shoshoni), Austronesian (Muna and Nancowry), Bantu (Tsonga), and Indo European (English and Spanish). The following articles…

  13. Quest to validate and define performance for the high volume metallic stator PCP at 250 degrees Celsius

    Energy Technology Data Exchange (ETDEWEB)

    Noonan, S.G. [ConocoPhillips Co., Houston, TX (United States); Klaczek, W.; Piers, K. [C-FER Technologies, Edmonton, AB (Canada); Seince, L. [PCM USA Inc., Houston, TX (United States); Jahn, S. [Kudu Industries, Calgary, AB (Canada)

    2008-10-15

    ConocoPhillips has been searching for a high volume artificial lift system that will reliably operate in a 250 degree Celsius downhole environment to meet the needs of steam assisted gravity drainage (SAGD) operations. This paper described the complexity of building and operating a high temperature flow loop rated for 250 degrees Celsius. It also described the lessons learned while upgrading an existing flow loop, from the initial design, procurement and construction through to the final commissioning phases. The paper described the issues encountered with the first artificial lit system tested at 250 degrees Celsius. The system consisted of a metallic progressing cavity pump system rated for 6919 barrels per day at 500 rotations per minute. The final upgraded capabilities of the flow loop were also listed. Images of the upgraded flow loop were also provided. It was concluded that the test program not only served to validate and define the pump's performance, but also provided valuable lessons on the completion configuration and operational procedures. Testing new artificial lift technology in a controlled flow loop, rather than in field installation, provided the opportunity to test these pumping systems under a large variety of conditions to truly understand the performance and limitations of each pump. 3 refs., 1 tab., 5 figs.

  14. Derivation of Plastic Work Rate Done per Unit Volume for Mean Yield Criterion and Its Application

    Institute of Scientific and Technical Information of China (English)

    Dewen ZHAO; Yingjie XIE; Xiaowen WANG; Xianghua LIU

    2005-01-01

    In Haigh Westergaard stress space linear combination of twin shear stress and Tresca yield functions is called the mean yield (MY) criterion. The mathematical relationship of the criterion and its plastic work rate done per unit volume were derived. A generalized worked example of slab forging was analyzed by the criterion and its corresponding plastic work rate done per unit volume. Then, the precision of the solution was compared with those by Mises and Twin shear stress yield criterions, respectively. It turned out that the calculated results by MY criterion were in good agreement with those by Mises criterion.

  15. Work Papers of the Summer Institute of Linguistics, University of North Dakota Session, Volume 24.

    Science.gov (United States)

    Daly, John P.; Daly, Margaret H.

    The working papers in this volume, written by staff and advanced students of the Summer Institute of Linguistics at the University of North Dakota, include the following: "The Antigone Constraint" (David Tuggy); "Clause Types in Southeastern Tepehuan" (Thomas L. Willett); "Sentence Components in Southeastern Tepehuan" (Thomas L. Willett); "Ethical…

  16. Work Papers of the Summer Intitute of Linguistics, 1993. University of North Dakota Session, Volume 37.

    Science.gov (United States)

    Dooley, Robert A., Ed.; Meyer, Jim, Ed.

    This volume of work papers from the Summer Institute of Linguistics includes the following: "Goals and Indirect Objects in Seri" (Stephen A. Marlett); "Seri Kinship Terminology" (Mary B. Moser and Stephen A. Marlett); "Quiegolani Zapotec Phonology" (Sue Regnier); "Role and Reference Grammar" (Robert D. Van Valin, Jr.); "The Binding Properties of…

  17. Deduction of plastic work rate per unit volume for unified yield criterion and its application

    Institute of Scientific and Technical Information of China (English)

    ZHAO De-wen; LI Jing; LIU Xiang-hua; WANG Guo-dong

    2009-01-01

    A unified linear expression of plastic work rate per unit volume is deduced from the unified linear yield criterion and the associated flow rule. The expression is suitable for various linear yield loci in the error triangle between Tresca's and twin shear stress yield loci on the π-plane. It exhibits generalization in which the different value of criterion parameter b corresponds to a specific linear formula of plastic work rate per unit volume. Finally, with the unified linear expression of plastic work rate and upper-bound parallel velocity field the strip forging without bulge is successfully analyzed and an analytical result is also obtained. The comparison with traditional solutions shows that when b=1/(1+(√3)) the result is the same as the upper bound result by Mises' yield criterion, and it also is identical to that by slab method with m=1, σ0=0.

  18. Digital Drug Dosing: Dosing in Drug Assays by Light-Defined Volumes of Hydrogels with Embedded Drug-Loaded Nanoparticles

    DEFF Research Database (Denmark)

    Faralli, Adele; Melander, Fredrik; Larsen, Esben Kjær Unmack;

    2014-01-01

    Polyethylene glycol (PEG)-based hydrogels are widely used for biomedical applications, including matrices for controlled drug release. We present a method for defining drug dosing in screening assays by light-activated cross-linking of PEG-diacrylate hydrogels with embedded drug-loaded liposome...

  19. A comparison study between gross tumor volumes defined by preoperative magnetic resonance imaging, postoperative specimens, and tumor bed for radiotherapy after breast-conserving surgery

    Science.gov (United States)

    Zhang, Aiping; Li, Jianbin; Wang, Wei; Wang, Yongsheng; Mu, Dianbin; Chen, Zhaoqiu; Shao, Qian; Li, Fengxiang

    2017-01-01

    Abstract Background: The identification and contouring of target volume is important for breast-conserving therapy. The aim of the study was to compare preoperative magnetic resonance imaging (MRI), postoperative pathology, excised specimens’ (ES) size, and tumor bed (TB) delineation as methods for determining the gross tumor volume (GTV) for radiotherapy after breast-conserving surgery (BCS). Methods: Thirty-three patients with breast cancer who underwent preoperative MRI and radiotherapy after BCS were enrolled. The GTVs determined by MRI, pathology, and the ES were defined as GTVMRI, GTVPAT, and GTVES, respectively. GTVMRI+1 was defined as a 1.0-cm margin around the GTVMRI. The radiation oncologist delineated GTV of the TB (GTVTB) using planning computed tomography according to ≥5 surgical clips placed in the lumpectomy cavity (LC). Results: The median GTVMRI, GTVMRI+1, GTVPAT, GTVES, and GTVTB were 0.97 cm3 (range, 0.01–6.88), 12.58 cm3 (range, 3.90–34.13), 0.97 cm3 (range, 0.01–6.36), 15.46 cm3 (range, 1.15–70.69), and 19.24 cm3 (range, 4.72–54.33), respectively. There were no significant differences between GTVMRI and GTVPAT, GTVMRI+1 and GTVES, GTVES and GTVTB (P = 0.188, 0.070, and 0.264, respectively). GTVMRI is positively related with GTVPAT. However, neither GTVES nor GTVTB correlated with GTVMRI (P = 0.071 and 0.378, respectively). Furthermore, neither GTVES nor GTVTB correlated with GTVMRI+1 (P = 0.068 and 0.375, respectively). Conclusion: When ≥5 surgical clips were placed in the LC for BCS, the volume of TB was consistent with the volume of ES. Neither the volume of TB nor the volume of ES correlated significantly with the volume of tumor defined by preoperative MRI. PMID:28079816

  20. Defining active sacroiliitis on MRI for classification of axial spondyloarthritis: update by the ASAS MRI working group.

    Science.gov (United States)

    Lambert, Robert G W; Bakker, Pauline A C; van der Heijde, Désirée; Weber, Ulrich; Rudwaleit, Martin; Hermann, K G; Sieper, Joachim; Baraliakos, Xenofon; Bennett, Alex; Braun, Jürgen; Burgos-Vargas, Rubén; Dougados, Maxime; Pedersen, Susanne Juhl; Jurik, Anne Grethe; Maksymowych, Walter P; Marzo-Ortega, Helena; Østergaard, Mikkel; Poddubnyy, Denis; Reijnierse, Monique; van den Bosch, Filip; van der Horst-Bruinsma, Irene; Landewé, Robert

    2016-11-01

    To review and update the existing definition of a positive MRI for classification of axial spondyloarthritis (SpA). The Assessment in SpondyloArthritis International Society (ASAS) MRI working group conducted a consensus exercise to review the definition of a positive MRI for inclusion in the ASAS classification criteria of axial SpA. Existing definitions and new data relevant to the MRI diagnosis and classification of sacroiliitis and spondylitis in axial SpA, published since the ASAS definition first appeared in print in 2009, were reviewed and discussed. The precise wording of the existing definition was examined in detail and the data and a draft proposal were presented to and voted on by the ASAS membership. The clear presence of bone marrow oedema on MRI in subchondral bone is still considered to be the defining observation that determines the presence of active sacroiliitis. Structural damage lesions seen on MRI may contribute to a decision by the observer that inflammatory lesions are genuinely due to SpA but are not required to meet the definition. The existing definition was clarified adding guidelines and images to assist in the application of the definition. The definition of a positive MRI for classification of axial SpA should continue to primarily depend on the imaging features of 'active sacroiliitis' until more data are available regarding MRI features of structural damage in the sacroiliac joint and MRI features in the spine and their utility when used for classification purposes. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.

  1. Effect of the 16-hour work limit on general surgery intern operative case volume: a multi-institutional study.

    Science.gov (United States)

    Schwartz, Samuel I; Galante, Joseph; Kaji, Amy; Dolich, Matthew; Easter, David; Melcher, Marc L; Patel, Kevin; Reeves, Mark E; Salim, Ali; Senagore, Anthony J; Takanishi, Danny M; de Virgilio, Christian

    2013-09-01

    The 80-hour work-week limit for all residents was instituted in 2003 and studies looking at its effect have been mixed. Since the advent of the 16-hour mandate for postgraduate year 1 residents in July 2011, no data have been published regarding the effect of this additional work-hour restriction. To determine whether the 16-hour intern work limit, implemented in July 2011, has adversely affected operative experience. A retrospective review of categorical postgraduate year 1 Accreditation Council for Graduate Medical Education case logs from the intern class (N = 52) (with 16-hour work limit) compared with the 4 preceding years (2007-2010; N = 197) (without 16-hour work limit). A total of 249 categorical general surgery interns from 10 general surgery residency programs in the western United States were included. Total, major, first-assistant, and defined-category case totals. As compared with the preceding 4 years, the 2011-2012 interns recorded a 25.8% decrease in total operative cases (65.9 vs 88.8, P = .005), a 31.8% decrease in major cases (54.9 vs 80.5, P intern era, whereas there was no decrease in trauma, vascular, alimentary, endoscopy, liver, and pancreas cases. The 16-hour work limit for interns, implemented in July 2011, is associated with a significant decrease in categorical intern operative experience. If the 16-hour shift were to be extended to all postgraduate year levels, one can anticipate that additional years of training will be needed to maintain the same operative volume.

  2. Comparison of internal target volumes defined on 3-dimensional, 4-dimensonal, and cone-beam CT images of non-small-cell lung cancer

    Directory of Open Access Journals (Sweden)

    Li F

    2016-11-01

    Full Text Available Fengxiang Li,1 Jianbin Li,1 Zhifang Ma,1 Yingjie Zhang,1 Jun Xing,1 Huanpeng Qi,1 Dongping Shang21Department of Radiation Oncology, 2Department of Big Bore CT Room, Shandong Cancer Hospital Affiliated to Shandong University, Shandong Academy of Medical Sciences, Jinan, Shandong, People’s Republic of ChinaPurpose: The purpose of this study was to compare the positional and volumetric differences of internal target volumes defined on three-dimensional computed tomography (3DCT, four-dimensional CT (4DCT, and cone-beam CT (CBCT images of non-small-cell lung cancer (NSCLC. Materials and methods: Thirty-one patients with NSCLC sequentially underwent 3DCT and 4DCT simulation scans of the thorax during free breathing. The first CBCT was performed and registered to the planning CT using the bony anatomy registration during radiotherapy. The gross tumor volumes were contoured on the basis of 3DCT, maximum intensity projection (MIP of 4DCT, and CBCT. CTV3D (clinical target volume, internal target volumes, ITVMIP and ITVCBCT, were defined with a 7 mm margin accounting for microscopic disease. ITV10 mm and ITV5 mm were defined on the basis of CTV3D: ITV10 mm with a 5 mm margin in left–right (LR, anterior–posterior (AP directions and 10 mm in cranial–caudal (CC direction; ITV5 mm with an isotropic internal margin (IM of 5 mm. The differences in the position, size, Dice’s similarity coefficient (DSC and inclusion relation of different volumes were evaluated.Results: The median size ratios of ITV10 mm, ITV5 mm, and ITVMIP to ITVCBCT were 2.33, 1.88, and 1.03, respectively, for tumors in the upper lobe and 2.13, 1.76, and 1.1, respectively, for tumors in the middle-lower lobe. The median DSCs of ITV10 mm, ITV5 mm, ITVMIP, and ITVCBCT were 0.6, 0.66, and 0.83 for all patients. The median percentages of ITVCBCT not included in ITV10 mm, ITV5 mm, and ITVMIP were 0.1%, 1.63%, and 15.21%, respectively, while the median percentages of ITV10 mm, ITV5 mm

  3. Vanishing linear term in chemical potential difference in volume term of work of critical nucleus formation for phase transition without volume change

    CERN Document Server

    Mori, Atsushi

    2013-01-01

    A question is given on the form n({\\mu}_{\\beta}-{\\mu}_{\\alpha}) for the volume term of work of formation of critical nucleus. Here, n is the number of molecule undergone the phase transition, {\\mu} denotes the chemical potential, {\\alpha} and {\\beta} represent the parent and nucleating phases, respectively. In this paper we concentrate phase transition without volume change. We have calculated the volume term in terms of the chemical potential difference {\\mu}_{re}-{\\mu}_{eq}$ for this case. Here, {\\mu}_{re} is the chemical potential of the reservoir and {\\mu}_{eq} that at the phase transition. We have W_{vol} = -[({\\kappa}_{\\beta}-{\\kappa}_{\\alpha})/(2v_{eq}^2)] ({\\mu}_{re}-{\\mu}_{eq})^2 V_{\\beta} with {\\kappa} denoting the isothermal compressibility, v_{eq} being the molecular volume at the phase transition, V_{\\beta} the volume of the nucleus.

  4. Locating Mothers: How Cultural Debates about Stay-at-Home versus Working Mothers Define Women and Home

    Science.gov (United States)

    Dillaway, Heather; Pare, Elizabeth

    2008-01-01

    Most women must decide whether to work for pay while mothering or make mothering their sole social role. Often this decision is portrayed in terms of whether they will be "stay-at-home" and presumably "full-time" mothers, or "working mothers" and therefore ones who prioritize paid work over caregiving. Inferred within this construction is women's…

  5. Survivor-Defined Practice in Domestic Violence Work: Measure Development and Preliminary Evidence of Link to Empowerment.

    Science.gov (United States)

    Goodman, Lisa A; Thomas, Kristie; Cattaneo, Lauren Bennett; Heimel, Deborah; Woulfe, Julie; Chong, Siu Kwan

    2016-01-01

    Survivor-defined practice, characterized by an emphasis on client choice, partnership, and sensitivity to the unique needs, contexts, and coping strategies of individual survivors, is an aspirational goal of the domestic violence (DV) movement, assumed to be a key contributor to empowerment and other positive outcomes among survivors. Despite its central role in DV program philosophy, training, and practice, however, our ability to assess its presence and its presumed link to well-being has been hampered by the absence of a way to measure it from survivors' perspectives. As part of a larger university-community collaboration, this study had two aims: (a) to develop a measure of survivor-defined practice from the perspective of participants, and (b) to assess its relationship to safety-related empowerment after controlling for other contributors to survivor well-being (e.g., financial stability and social support). Results supported the reliability and validity of the Survivor-Defined Practice Scale (SDPS), a nine-item measure that assesses participants' perception of the degree to which their advocates help them achieve goals they set for themselves, facilitate a spirit of partnership, and show sensitivity to their individual needs and styles. The items combined to form one factor indicating that the three theoretical aspects of survivor-defined practice may be different manifestations of one underlying construct. Results also support the hypothesized link between survivor-defined practice and safety-related empowerment. The SDPS offers DV programs a mechanism for process evaluation that is rigorous and rooted in the feminist empowerment philosophy that so many programs espouse.

  6. Press On! Selected Works of General Donn A. Starry. Volume 2

    Science.gov (United States)

    2009-01-01

    values” it might wither on the vine . Maybe. Maybe not. We don’t think so—what we do think is that no one has yet defined very clearly what is being...was largely populated by people who worked at Bethlehem’s Sparrow’s Point steel mill. A lot of military people lived on our block...the first submarine to surface through the ice at the North Pole . Later he commanded the Second Fleet and was Superintendent at Annapolis. He was a

  7. SU-E-J-119: What Effect Have the Volume Defined in the Alignment Clipbox for Cervical Cancer Using Automatic Registration Methods for Cone- Beam CT Verification?

    Energy Technology Data Exchange (ETDEWEB)

    Wang, W; Yang, H; Wang, Y; Jia, H; Xie, Y [Taizhou Hospital, Wenzhou Medical College, Taizhou, Zhejiang (China)

    2014-06-01

    Purpose: To investigate the impact of different clipbox volumes with automated registration techniques using commercially available software with on board volumetric imaging(OBI) for treatment verification in cervical cancer patients. Methods: Fifty cervical cancer patients received daily CBCT scans(on-board imaging v1.5 system, Varian Medical Systems) during the first treatment week and weekly thereafter were included this analysis. A total of 450 CBCT scans were registered to the planning CTscan using pelvic clipbox(clipbox-Pelvic) and around PTV clip box(clipbox- PTV). The translations(anterior-posterior, left-right, superior-inferior) and the rotations(yaw, pitch and roll) errors for each matches were recorded. The setup errors and the systematic and random errors for both of the clip-boxes were calculated. Paired Samples t test was used to analysis the differences between clipbox-Pelvic and clipbox-PTV. Results: . The SD of systematic error(σ) was 1.0mm, 2.0mm,3.2mm and 1.9mm,2.3mm, 3.0mm in the AP, LR and SI directions for clipbox-Pelvic and clipbox-PTV, respectively. The average random error(Σ)was 1.7mm, 2.0mm,4.2mm and 1.7mm,3.4mm, 4.4mm in the AP, LR and SI directions for clipbox-Pelvic and clipbox-PTV, respectively. But, only the SI direction was acquired significantly differences between two image registration volumes(p=0.002,p=0.01 for mean and SD). For rotations, the yaw mean/SD and the pitch SD were acquired significantly differences between clipbox-Pelvic and clipbox-PTV. Conclusion: The defined volume for Image registration is important for cervical cancer when 3D/3D match was used. The alignment clipbox can effect the setup errors obtained. Further analysis is need to determine the optimal defined volume to use the image registration in cervical cancer. Conflict of interest: none.

  8. Psychological intervention with working memory training increases basal ganglia volume: A VBM study of inpatient treatment for methamphetamine use

    Directory of Open Access Journals (Sweden)

    S.J. Brooks, PhD

    2016-01-01

    Conclusions: While psychological intervention is associated with larger volume in mesolimbic reward regions, the utilisation of additional working memory training as an adjunct to treatment may further normalize frontostriatal structure and function.

  9. A Re-Examination of Defining Moments in Vygotsky's Work and Their Implications for His Continuing Legacy

    Science.gov (United States)

    Gonzalez Rey, Fernando

    2011-01-01

    This article argues for the idea of different moments in Vygotsky's work while highlighting combinations of ideas and concepts that were particularly emphasized in distinct moments of his work. After Vygotsky's death, these moments were not considered a theoretical system in development, either in former Soviet psychology or in Western…

  10. A Re-Examination of Defining Moments in Vygotsky's Work and Their Implications for His Continuing Legacy

    Science.gov (United States)

    Gonzalez Rey, Fernando

    2011-01-01

    This article argues for the idea of different moments in Vygotsky's work while highlighting combinations of ideas and concepts that were particularly emphasized in distinct moments of his work. After Vygotsky's death, these moments were not considered a theoretical system in development, either in former Soviet psychology or in Western…

  11. The work compatibility improvement framework: preliminary findings of a case study for defining and measuring the human-at-work system.

    Science.gov (United States)

    Genaidy, A; Karwowski, W; A-Rehim, A

    2007-11-01

    Although researchers traditionally examined the 'risk' characteristics of work settings in health studies, few work models, such as the 'demand-control' and 'motivation-hygiene theory', advocated the study of the positive and the negative aspects of work for the ultimate improvement of work performance. The objectives of the current study were: (a) to examine the positive and negative characteristics of work in the machining department in a small manufacturing plant in the Midwest USA, and, (b) to report the prevalence of musculoskeletal and stress outcomes. A focus group consisting of worker experts from the different job categories in the machining department confirmed the management's concerns. Accordingly, 56 male and female workers, employed in three shifts, were surveyed on the demand/energizer profiles of work characteristics and self-reported musculoskeletal/stress symptoms. On average, one-fourth to one-third of the workers reported 'high' demand, and over 50% of the workers documented 'low' energizers for certain work domains/sub-domains, such as 'physical task content'/'organizational' work domains and 'upper body postural loading'/'time organization' work sub-domains. The prevalence of workers who reported 'high' musculoskeletal/stress disorder cases, was in the range of 25-35% and was consistent with the results of 'high' demands and 'low' energizers. The results of this case study confirm the importance of adopting a comprehensive view for work improvement and sustainable growth opportunities. It is paramount to consider the negative and positive aspects of work characteristics to ensure optimum organizational performance. The Work Compatibility Improvement Framework, proposed in the reported research, is an important endeavor toward the ultimate improvement and sustainable growth of human and organizational performance.

  12. Coyote Papers: The University of Arizona Working Papers in Linguistics, Volume 11. Special Volume on Native American Languages.

    Science.gov (United States)

    Weinberg, Jessica P., Ed.; O'Bryan, Erin L., Ed.; Moll, Laura A., Ed.; Haugan, Jason D., Ed.

    The five papers included in this volume approach the study of American Indian languages from a diverse array of methodological and theoretical approaches to linguistics. Two papers focus on approaches that come from the applied linguistics tradition, emphasizing ethnolinguistics and discourse analysis: Sonya Bird's paper "A Cross Cultural Look at…

  13. Fat-suppressed volume isotropic turbo spin echo acquisition (VISTA) MR imaging in evaluating radial and root tears of the meniscus: Focusing on reader-defined axial reconstruction

    Energy Technology Data Exchange (ETDEWEB)

    Lim, Daekeon; Lee, Young Han; Kim, Sungjun; Song, Ho-Taek; Suh, Jin-Suck, E-mail: jss@yuhs.ac

    2013-12-01

    Objective: To assess the diagnostic value of fat-suppressed (FS) three-dimensional (3D) volume isotropic turbo spin echo acquisition (VISTA) imaging in detecting radial and root tears of the meniscus, including the reader-defined reformatted axial (RDA) plane. Materials and methods: Twenty-three patients with arthroscopically confirmed radial or root tears of the meniscus underwent magnetic resonance imaging (MRI) with 2D and FS 3D VISTA sequences. MRIs were reviewed independently by two musculoskeletal radiologists blinded to the arthroscopic findings. Sensitivity, specificity, accuracy, and interobserver agreement were calculated for radial and root tears. Both radiologists reported confidence scale for the presence of meniscal tears in 2D axial imaging, 3D axial imaging, and RDA imaging, based on a five-point scale. Wilcoxon's signed rank test was used to compare confidence scale. Results: The sensitivity, specificity, and accuracy of FS 3D VISTA MR imaging versus 2D MR imaging were as follows: 96%, 96%, and 96% versus 91%, 91%, and 91%, respectively in reader 1, and 96%, 96%, and 96% versus 83%, 91%, and 87%, respectively, in reader 2. Interobserver agreement for detecting meniscal tears was excellent (κ = 1) with FS 3D VISTA. The confidence scale was significantly higher for 3D axial images than 2D imaging (p = 0.03) and significantly higher in RDA images than 3D axial image in detecting radial and root tears. Conclusions: FS 3D VISTA had a better diagnostic performance in evaluating radial and root tears of the meniscus. The reader-defined reformatted axial plane obtained from FS 3D VISTA MR imaging is useful in detecting radial and root tears of the meniscus.

  14. Defining active sacroiliitis on MRI for classification of axial spondyloarthritis: update by the ASAS MRI working group

    DEFF Research Database (Denmark)

    Lambert, Robert G W; Bakker, Pauline A C; van der Heijde, Désirée

    2016-01-01

    . CONCLUSION: The definition of a positive MRI for classification of axial SpA should continue to primarily depend on the imaging features of 'active sacroiliitis' until more data are available regarding MRI features of structural damage in the sacroiliac joint and MRI features in the spine and their utility......OBJECTIVES: To review and update the existing definition of a positive MRI for classification of axial spondyloarthritis (SpA). METHODS: The Assessment in SpondyloArthritis International Society (ASAS) MRI working group conducted a consensus exercise to review the definition of a positive MRI...... for inclusion in the ASAS classification criteria of axial SpA. Existing definitions and new data relevant to the MRI diagnosis and classification of sacroiliitis and spondylitis in axial SpA, published since the ASAS definition first appeared in print in 2009, were reviewed and discussed. The precise wording...

  15. Skin Cancer of the Head and Neck with Perineural Invasion: Defining the Clinical Target Volumes Based on the Pattern of Failure

    Science.gov (United States)

    Gluck, Iris; Ibrahim, Mohannad; Popovtzer, Aron; Teknos, Theodoros N.; Chepeha, Douglas B; Prince, Mark E; Moyer, Jeffrey S; Bradford, Carol R; Eisbruch, Avraham

    2009-01-01

    Purpose To analyze patterns of failure in patients with head and neck cutaneous squamous cell carcinoma (HNCSCC) and clinical/radiological evidence of perineural invasion (CPNI), in order to define neural clinical target volume (CTV) for treatment planning. Methods Patients treated with 3D conformal or intensity modulated radiotherapy (IMRT) for HNCSCC with CPNI were included in the study. A retrospective review of the clinical charts, radiotherapy (RT) plans and radiological studies has been conducted. Results Eleven consecutive patients with HNCSCCs with CPNI were treated from 2000 through 2007. Most patients received multiple surgical procedures and RT courses. The most prevalent failure pattern was along cranial nerves (CNs), and multiple CNs were ultimately involved in the majority of cases. In all cases the involved CNs at recurrence were the main nerves innervating the primary tumor sites, as well as their major communicating nerves. We have found several distinct patterns of disease spread along specific CNs depending on the skin regions harboring the primary tumors, including multiple branches of CN V and VII. These patterns and the pertinent anatomy are detailed in the paper. Conclusions Predictable disease spread patterns along cranial nerves supplying the primary tumor sites were found in this study. Awareness of these patterns, as well as knowledge of the relevant cranial nerve anatomy, should be the basis for CTV definition and delineation for RT treatment planning. PMID:18938044

  16. Savannah River Plant engineering, design, and construction history of ``S`` projects and other work, January 1961--December 1964. Volume 2

    Energy Technology Data Exchange (ETDEWEB)

    1970-03-01

    The work described in this volume of ``S`` Projects History is an extension of the type of work described in Volume I. E.I. du Pont de flemours & Company had entered into Contract AT (07-2)-l with the United States Atomic Energy Commission to develop, design, construct, install, and operate facilities to produce heavy water, fissionable materials, and related products. Under this contract,, Du Pont constructed and operated the Savannah River Plant. The engineering, design, and construction for most of the larger ``S`` projects was performed by the Engineering DeDartment. For some of the large and many of the smaller projects the Engineering Department was responsible only for the construction because the Atomic Energy Division (AED) of the Explosives Department handled the other phases. The Engineering Department Costruction Division also performed the physical work for many of the plant work orders. This volume includes a general description of the Du Pont Engineering Department activities pertaining to the engineering, design, and construction of the ``S`` projects at the Savannah River Plant; brief summaries of the projects and principal work requests; and supplementary informaticn on a few subjects in Volume I for which final data was not available at the closing date. Projects and other plant engineering work which were handled entirely by the Explosives Department -- AED are not included in this history.

  17. Effects of pH amendment on metal working fluid wastewater biological treatment using a defined bacterial consortium.

    Science.gov (United States)

    van der Gast, Christopher J; Thompson, Ian P

    2005-02-05

    The aim of this study was to determine whether pH amendment of a highly alkaline metal working fluid (MWF) wastewater would improve biological treatment in a bioreactor system following introduction of a bacterial inoculum (comprised of the following strains: Agrobacterium radiobacter, Comamonas testosteroni, Methylobacterium mesophilicum, Microbacterium esteraromaticum, and Microbacterium saperdae). The pH values tested were 6, 7, 8, and 9. Three replicate batch mode bioreactors inoculated with the bacterial inoculum (plus an abiotic control bioreactor) were operated for each of the four pH conditions. After 14 days, the final mean chemical oxygen demand (COD) reduction at pH 9 was 50 +/- 1.4%; at pH 8, 58 +/- 1.4%; pH 7, 65 +/- 1.0%; and pH 6, 75 +/- 2.7% of the initial COD (approximately 10,000 mg L(-1)), respectively. Interestingly, within 5 days, the pH in all inoculated bioreactors progressed toward pH 8. However, all abiotic control bioreactors remained at the pH at which they were amended. The fate of the inoculum, determined by denaturing gradient gel electrophoresis (DGGE) and by cluster analysis of the resulting DGGE profiles, revealed that the inocula survived throughout operation of all pH-amended bioreactors. Length-heterogeneity polymerase chain reaction (PCR) was used to track the population dynamics of individual strains. After 7 days of operation, M. esteraromaticum was the most abundant population in all bioreactors, regardless of pH. From our findings, it appears necessary to adjust the MWF wastewater from pH 9 to between 6 and 7, to achieve optimal biological treatment rates.

  18. Intermediate volume on computed tomography imaging defines a fibrotic compartment that predicts glomerular filtration rate decline in autosomal dominant polycystic kidney disease patients.

    Science.gov (United States)

    Caroli, Anna; Antiga, Luca; Conti, Sara; Sonzogni, Aurelio; Fasolini, Giorgio; Ondei, Patrizia; Perico, Norberto; Remuzzi, Giuseppe; Remuzzi, Andrea

    2011-08-01

    Total kidney and cyst volumes have been used to quantify disease progression in autosomal dominant polycystic kidney disease (ADPKD), but a causal relationship with progression to renal failure has not been demonstrated. Advanced image processing recently allowed to quantify extracystic tissue, and to identify an additional tissue component named "intermediate," appearing hypoenhanced on contrast-enhanced computed tomography (CT). The aim of this study is to provide a histological characterization of intermediate volume, investigate its relation with renal function, and provide preliminary evidence of its role in long-term prediction of functional loss. Three ADPKD patients underwent contrast-enhanced CT scans before nephrectomy. Histological samples of intermediate volume were drawn from the excised kidneys, and stained with hematoxylin and eosin and with saturated picrosirius solution for histological analysis. Intermediate volume showed major structural changes, characterized by tubular dilation and atrophy, microcysts, inflammatory cell infiltrate, vascular sclerosis, and extended peritubular interstitial fibrosis. A significant correlation (r = -0.69, P < 0.001) between relative intermediate volume and baseline renal function was found in 21 ADPKD patients. Long-term prediction of renal functional loss was investigated in an independent cohort of 13 ADPKD patients, followed for 3 to 8 years. Intermediate volume, but not total kidney or cyst volume, significantly correlated with glomerular filtration rate decline (r = -0.79, P < 0.005). These findings suggest that intermediate volume may represent a suitable surrogate marker of ADPKD progression and a novel therapeutic target.

  19. Manned remote work station development article. Volume 1, book 2, appendix B: Trade and design definition studies

    Science.gov (United States)

    1979-01-01

    System trades, evaluations, and selection were organized under the appropriate manned remote work station roles and subsystems. Those trades/evaluations that have an impact on simulator fidelity were given emphasis in terms of identifying alternate concepts, making a selection, and defining the system approach. Those trades that do not impact simulator fidelity have the issues delineated and future study requirements identified.

  20. Propulsion and Energetics Panel Working Group 11 on Aircraft Fire Safety. Volume 2. Main Report

    Science.gov (United States)

    1979-11-01

    Figure 4.1, this volume is subjected to: (1) Intrusion of flames to act as an ignition source in A; (2) A heat flux due to the external fire around...where there could be a risk of fire or explosion. (e) the risk of explosion resulting from penetration of the vapour space of fuel tanks. (f) damage

  1. Defining excellence.

    Science.gov (United States)

    Mehl, B

    1993-05-01

    Excellence in the pharmacy profession, particularly pharmacy management, is defined. Several factors have a significant effect on the ability to reach a given level of excellence. The first is the economic and political climate in which pharmacists practice. Stricter controls, reduced resources, and the velocity of change all necessitate nurturing of values and a work ethic to maintain excellence. Excellence must be measured by the services provided with regard to the resources available; thus, the ability to achieve excellence is a true test of leadership and innovation. Excellence is also time dependent, and today's innovation becomes tomorrow's standard. Programs that raise the level of patient care, not those that aggrandize the profession, are the most important. In addition, basic services must be practiced at a level of excellence. Quality assessment is a way to improve care and bring medical treatment to a higher plane of excellence. For such assessment to be effective and not punitive, the philosophy of the program must be known, and the goal must be clear. Excellence in practice is dependent on factors such as political and social norms, standards of practice, available resources; perceptions, time, the motivation to progress to a higher level, and the continuous innovation required to reshape the profession to meet the needs of society.

  2. Comparison of target volumes in radiotherapy defined on scanner and on PET-T.D.M. with {sup 18}F-F.D.G. in the frame of head and neck cancers; Comparaison des volumes cibles en radiotherapie definis sur scanner et sur TEP-TDM au 18F FDG dans le cadre des cancers de la tete et du cou

    Energy Technology Data Exchange (ETDEWEB)

    Henriques De Figueiredo, B.; Barret, O.; Allard, M.; Fernandez, P. [Service de medecine nucleaire, CHU de Pellegrin, Bordeaux, (France); Demeaux, H.; Maire, J.P.; Lagarde, P. [service de radiotherapie, hopital Saint-Andre, Bordeaux, (France); Kantor, G.; Richau, P. [departement de radiotherapie, institut Bergonie, Bordeaux, (France); De Mones Del Pujol, E. [service d' ORL, hopital Pellegrin, Bordeaux, (France)

    2009-05-15

    The objective is to study in a prospective way, in the frame of head and neck cancers, the impact of the positron computed tomography with {sup 18}F fluorodeoxyglucose (PET-F.D.G.) on the limitation of target volumes in radiotherapy. In conclusions, the gross tumor volume (G.T.V.) defined on PET is smaller than this one defined on scanner, that could be interesting in radiotherapy, in the perspective of a dose escalation. In addition, areas of discordance exist between the clinical target volumes (C.T.V.70 and C.T.V.50) defined on PET and on scanner. These discordances, synonyms of under or over estimation of target volumes, could have important clinical consequences in term of local control and toxicity. (N.C.)

  3. Introduction to Working Memory. NetNews. Volume 7, Number 4

    Science.gov (United States)

    LDA of Minnesota, 2007

    2007-01-01

    Working memory has been called the "door to learning" (think the library) and is strongly related to performance in reading comprehension and problem-solving. Persons with strong working memory have a wide open door for acquiring all types of new information. They are able to hang on to new information, work with it, integrate it with lots of…

  4. 物理化学中体积功的计算%Calculation of Volume Work in Physical Chemistry

    Institute of Scientific and Technical Information of China (English)

    沈广宇; 张春香

    2015-01-01

    Physical Chemistry is an important basic course of Chemistry, Chemical Engineering, and other special fields. It plays an important role in daily life and scientific studies. The first law of thermodynamics is the basic content of Physical Chemistry. Calculation of volume work is an important step in the application of first law of thermodynamics. According to the formula for calculating volume work, the calculation methods of volume work of several common processes were summarized, including free expansion, isothermal process, adiabatic process, respectively.%物理化学是大学化学化工及其他相关专业的一门重要基础课,在日常生活和科学研究中起着重要的指导作用。热力学第一定律是物理化学的基础内容,而体积功的计算是正确理解和运用热力学第一定律的重要环节。本文阐述了正确理解和运用体积功计算公式应该注意的几个方面,并结合例题总结了常见几种过程如自由膨胀过程,等温过程,绝热过程等过程体积功的计算方法。

  5. North Africa - Working paper - Trade Volume and Economic Growth in the MENA Region: Goods or Services?

    OpenAIRE

    Jacob Kolster

    2015-01-01

    Key messages • The relatively important trade barriers do not only have a negative impact on service trade, but also on the competitiveness of manufacturing, especially that some services such as transport and telecommunication services as well as financial services are complementary to goods production and exports. • The study underline that trade in services and trade in goods both do increase gross domestic product as trade policy openness and higher ratios of trade volumes to gross domest...

  6. Volume rendering versus maximum intensity projection in CT angiography: what works best, when, and why.

    Science.gov (United States)

    Fishman, Elliot K; Ney, Derek R; Heath, David G; Corl, Frank M; Horton, Karen M; Johnson, Pamela T

    2006-01-01

    The introduction and widespread availability of 16-section multi-detector row computed tomographic (CT) technology and, more recently, 64-section scanners, has greatly advanced the role of CT angiography in clinical practice. CT angiography has become a key component of state-of-the-art imaging, with applications ranging from oncology (eg, staging of pancreatic or renal cancer) to classic vascular imaging (eg, evaluation of aortic aneurysms and renal artery stenoses) as well as newer techniques such as coronary artery imaging and peripheral runoff studies. With an average of 400-1000 images in each volume data set, three-dimensional postprocessing is crucial to volume visualization. Radiologists now have workstations that provide capabilities for evaluation of these data sets by using a range of software programs and processing tools. Although different systems have unique capabilities and functionality, all provide the options of volume rendering and maximum intensity projection for image display and analysis. These two postprocessing techniques have different advantages and disadvantages when used in clinical practice, and it is important that radiologists understand when and how each technique should be used. Copyright RSNA, 2006.

  7. Accomplishing Shipyard Work for the United States Navy: Institutions, Systems and Operations. Volume I. Basic Report

    Science.gov (United States)

    1975-08-01

    8217Standard Metropolitan Statistical Areas (SI4SAs) are 269 geographical areas making up the fifty states and Puerto Rico. These areas are defined by the U.S...8217 * (2) Development of revised basing policies to provide I~o ovrhals f telv mothsduration or longer, the Navy has a policy of teprrlycagn tesi ’ home

  8. Las obreras: Chicana Politics of Work and Family. Aztlan Anthology Series, Volume 1.

    Science.gov (United States)

    Ruiz, Vicki L., Ed.

    In this anthology, Chicana voices of the past and present illuminate the experiences of Mexican American women as they strive to integrate wage work, family life, and community engagement. Sections cover confrontations with the state through community action, court litigation, and union organizing; negotiating work, marriage, and children; stories…

  9. Humanization of work circumstances in dialog communication using data display devices, volume 1

    Science.gov (United States)

    Graunke, H.; Julich, H.; Petersen, H. C.; Schaefer, H.; Strupp, K.

    1982-11-01

    The effects of data display on working places was investigated. Data processing by data display devices is not considered. Important criteria for job contentment is the integration into complex job structures. Corresponding to this principle of organization is team work with a flexible way of labor division which provides the chance and the motivation for a cooperative self controlled working process which give strain caused by data display devices. It is found that in public administration a team with an institutional leadership with primarily social integrative functions is appreciated most.

  10. Defining the Most Accurate Measurable Dimension(s of the Liver in Predicting Liver Volume Based on CT Volumetery and Reconstruction

    Directory of Open Access Journals (Sweden)

    Reza Saadat Mostafavi

    2010-05-01

    Full Text Available Background/Objective: The presence of liver volume has a great effect on diagnosis and management of different diseases such as lymphoproliferative conditions. "nPatients and Methods: Abdominal CT scan of 100 patients without any findings for liver disease (in history and imaging was subjected to volumetry and reconstruction. Along with the liver volume, in axial series, the AP diameter of the left lobe (in midline and right lobe (mid-clavicular and lateral maximum diameter of the liver in the mid-axiliary line and maximum diameter to IVC were calculated. In the coronal mid-axillary and sagittal mid-clavicular plane, maximum superior-inferior dimensions were calculated with their various combinations (multiplying. Regression analysis between dimensions and volume were performed. "nResults: The most accurate combination was the superior inferior sagittal dimension multiplied by AP diameter of the right lobe (R squared 0.78, P-value<0.001 and the most solitary dimension was the lateral dimension to IVC in the axial plane (R squared 0.57, P-value<0.001 with an interval of 9-11cm for 68% of normal. "nConclusion: We recommend the lateral maximum diameter of liver from surface to IVC in the axial plane in ultrasound for liver volume prediction with an interval of 9-11cm for 68% of normal. Out of this range is regarded as abnormal.

  11. Patient resources in the therapeutic education of haemophiliacs in France: their skills and roles as defined by consensus of a working group.

    Science.gov (United States)

    Wintz, L; Sannié, T; Ayçaguer, S; Guerois, C; Bernhard, J-P; Valluet, D; Borel-Derlon, A; Guillon, P; Fondanesche, C; Lambert, T; Meunier, S; Alliaume, N; Gagnayre, R

    2010-05-01

    The activities of 'expert patients' or 'patient tutors', who help educate their peers, are gaining recognition in the health care system. This study investigates the role played by such patients in therapeutic education programmes organized by caregivers to validate the role of patients in implementing the therapeutic education of haemophilic patients and to define the skills required for such activities. This study employs the consensus methodology recommended by France's National Authority for Health. The working group includes seven caregivers from Hemophiliac Treatment Centers (HTCs) and three patients from the French Association of Hemophiliacs (FAH). The role of patients in haemophilia education is recognized. Patients participating in the education of their peers are referred to as 'patient resources'. A patient resource should be an adult, a volunteer and live in the same region as his peers. Candidates are chosen by the FAH and the HTCs to serve based on their motivation to facilitate the education of other patients as well as on their psychological and pedagogical aptitudes. A patient resource participates in the conception and administration of therapeutic education programmes. He also mediates between the caregivers and the patients. He ensures that the patients understand the material and are able to apply their knowledge in daily life. His activities are governed by professional ethics. Seven categories of skills were defined, permitting the group to determine precisely which skills are required to function as a patient resource. Supervision of the patients is planned to reinforce reflexive practices in the patients. Evolution of the health care system has led patients to become involved in therapeutic education. This phenomenon calls for a framework to be developed and an evaluation of its eventual effects.

  12. Estimation of an image derived input function with MR-defined carotid arteries in FDG-PET human studies using a novel partial volume correction method

    DEFF Research Database (Denmark)

    Sari, Hasan; Erlandsson, Kjell; Law, Ian

    2017-01-01

    Kinetic analysis of (18)F-fluorodeoxyglucose positron emission tomography data requires an accurate knowledge the arterial input function. The gold standard method to measure the arterial input function requires collection of arterial blood samples and is an invasive method. Measuring an image...... segmentation of the carotid arteries from MR images. The simulation study results showed that at least 92% of the true intensity could be recovered after the partial volume correction. Results from 19 subjects showed that the mean cerebral metabolic rate of glucose calculated using arterial samples and partial...... volume corrected image derived input function were 26.9 and 25.4 mg/min/100 g, respectively, for the grey matter and 7.2 and 6.7 mg/min/100 g for the white matter. No significant difference in the estimated cerebral metabolic rate of glucose values was observed between arterial samples and corrected...

  13. 1988 Work Papers of the Summer Institute of Linguistics, University of North Dakota Session. Volume 32.

    Science.gov (United States)

    Derbyshire, Desmond C., Ed.

    Six working papers in linguistics are presented. "The Semantics and Morphology of Mixtec Mood and Aspect" (J. Albert Bickford and Stephen A. Marlett) presents a relatively detailed description of the following grammatical categories in three Mixtec languages: Santiago Nuyoo, Santo Domingo Nuxaa, and Municipio of Tezoatlan.…

  14. Travaux Neuchatelois de Linguistique (TRANEL) (Neuchatel Working Papers in Linguistics), Volume 17.

    Science.gov (United States)

    Rubattel, Christian, Ed.

    1991-01-01

    Papers in linguistics in this issue include: "Aspects logico-semantiques de la metaphore" ("Logico-Semantic Aspects of the Metaphor") (Michel le Guern); "Metaphore et travail lexicale" ("Metaphor and Lexical Work") (Georges Ludi); "Aspects linguistiques et pragmatiques de la metaphore: anomalie…

  15. Work.

    Science.gov (United States)

    Haines, Annette M.

    2003-01-01

    Draws upon Maria Montessori's writings to examine work as a universal human tendency throughout life. Discusses the work of adaptation of the infant, work of "psycho-muscular organism" for the preschooler, work of the imagination for the elementary child, community work of the adolescent, and work of the adult. Asserts that…

  16. Volume term of work of critical nucleus formation in terms of chemical potential difference relative to equilibrium one

    CERN Document Server

    Mori, Atsushi

    2013-01-01

    The work of formation of a critical nucleus is sometimes written as W=n{\\Delta}{\\mu}+{\\gamma}A. The first term W_{vol}=n{\\Delta}{\\mu} is called the volume term and the second term {\\gamma}A the surface term with {\\gamma} being the interfacial tension and A the area of the nucleus. Nishioka and Kusaka [J. Chem. Phys. 96 (1992) 5370] derived W_{vol}=n{\\Delta}{\\mu} with n=V_{\\beta}/v_{\\beta} and {\\Delta}{\\mu}={\\mu}_{\\beta}(T,p_{\\alpha})-{\\mu}_{\\alpha}(T,p_{\\alpha}) by rewriting W_{vol}=-(p_{\\beta}-p_{\\alpha})V_{\\beta} by integrating the isothermal Gibbs-Duhem relation for an incompressible {\\beta} phase, where {\\alpha} and {\\beta} represent the parent and nucleating phases, V_{\\beta} is the volume of the nucleus, v_{\\beta}, which is constant, the molecular volume of the {\\beta} phase, {\\mu}, T, and p denote the chemical potential, the temperature, and the pressure, respectively. We note here that {\\Delta}{\\mu}={\\mu}_{\\beta}(T,p_{\\alpha})-{\\mu}_{\\alpha}(T,p_{\\alpha}) is, in general, not a directly measurable quan...

  17. Finite volume analysis of temperature effects induced by active MRI implants with cylindrical symmetry: 1. Properly working devices

    Directory of Open Access Journals (Sweden)

    Schnorr Jörg

    2005-04-01

    Full Text Available Abstract Background Active Magnetic Resonance Imaging implants are constructed as resonators tuned to the Larmor frequency of a magnetic resonance system with a specific field strength. The resonating circuit may be embedded into or added to the normal metallic implant structure. The resonators build inductively coupled wireless transmit and receive coils and can amplify the signal, normally decreased by eddy currents, inside metallic structures without affecting the rest of the spin ensemble. During magnetic resonance imaging the resonators generate heat, which is additional to the usual one described by the specific absorption rate. This induces temperature increases of the tissue around the circuit paths and inside the lumen of an active implant and may negatively influence patient safety. Methods This investigation provides an overview of the supplementary power absorbed by active implants with a cylindrical geometry, corresponding to vessel implants such as stents, stent grafts or vena cava filters. The knowledge of the overall absorbed power is used in a finite volume analysis to estimate temperature maps around different implant structures inside homogeneous tissue under worst-case assumptions. The "worst-case scenario" assumes thermal heat conduction without blood perfusion inside the tissue around the implant and mostly without any cooling due to blood flow inside vessels. Results The additional power loss of a resonator is proportional to the volume and the quality factor, as well as the field strength of the MRI system and the specific absorption rate of the applied sequence. For properly working devices the finite volume analysis showed only tolerable heating during MRI investigations in most cases. Only resonators transforming a few hundred mW into heat may reach temperature increases over 5 K. This requires resonators with volumes of several ten cubic centimeters, short inductor circuit paths with only a few 10 cm and a quality

  18. Impact of 18-fluorodeoxyglucose positron emission tomography on computed tomography defined target volumes in radiation treatment planning of esophageal cancer: reduction in geographic misses with equal inter-observer variability: PET/CT improves esophageal target definition.

    Science.gov (United States)

    Schreurs, L M A; Busz, D M; Paardekooper, G M R M; Beukema, J C; Jager, P L; Van der Jagt, E J; van Dam, G M; Groen, H; Plukker, J Th M; Langendijk, J A

    2010-08-01

    Target volume definition in modern radiotherapy is based on planning computed tomography (CT). So far, 18-fluorodeoxyglucose positron emission tomography (FDG-PET) has not been included in planning modality in volume definition of esophageal cancer. This study evaluates fusion of FDG-PET and CT in patients with esophageal cancer in terms of geographic misses and inter-observer variability in volume definition. In 28 esophageal cancer patients, gross, clinical and planning tumor volumes (GTV; CTV; PTV) were defined on planning CT by three radiation oncologists. After software-based emission tomography and computed tomography (PET/CT) fusion, tumor delineations were redefined by the same radiation-oncologists. Concordance indexes (CCI's) for CT and PET/CT based GTV, CTV and PTV were calculated for each pair of observers. Incorporation of PET/CT modified tumor delineation in 17/28 subjects (61%) in cranial and/or caudal direction. Mean concordance indexes for CT-based CTV and PTV were 72 (55-86)% and 77 (61-88)%, respectively, vs. 72 (47-99)% and 76 (54-87)% for PET/CT-based CTV and PTV. Paired analyses showed no significant difference in CCI between CT and PET/CT. Combining FDG-PET and CT may improve target volume definition with less geographic misses, but without significant effects on inter-observer variability in esophageal cancer.

  19. Genetic correlations between brain volumes and the WAIS-III dimensions of verbal comprehension, working memory, perceptual organization, and processing speed

    DEFF Research Database (Denmark)

    Posthuma, Daniëlle; Baare, Wim F.C.; Hulshoff Pol, Hilleke E.;

    2003-01-01

    to cerebellar volume. Verbal Comprehension was not related to any of the three brain volumes. It is concluded that brain volumes are genetically related to intelligence which suggests that genes that influence brain volume may also be important for intelligence. It is also noted however, that the direction......We recently showed that the correlation of gray and white matter volume with full scale IQ and the Working Memory dimension are completely mediated by common genetic factors (Posthuma et al., 2002). Here we examine whether the other WAIS III dimensions (Verbal Comprehension, Perceptual Organization...... to Working Memory capacity (r = 0.27). This phenotypic correlation is completely due to a common underlying genetic factor. Processing Speed was genetically related to white matter volume (r(g) = 0.39). Perceptual Organization was both genetically (r(g) = 0.39) and environmentally (r(e) = -0.71) related...

  20. Define Project

    DEFF Research Database (Denmark)

    Munk-Madsen, Andreas

    2005-01-01

    "Project" is a key concept in IS management. The word is frequently used in textbooks and standards. Yet we seldom find a precise definition of the concept. This paper discusses how to define the concept of a project. The proposed definition covers both heavily formalized projects and informally...... organized, agile projects. Based on the proposed definition popular existing definitions are discussed....

  1. GPACC program cost work breakdown structure-dictionary. General purpose aft cargo carrier study, volume 3

    Science.gov (United States)

    1985-01-01

    The results of detailed cost estimates and economic analysis performed on the updated Model 101 configuration of the general purpose Aft Cargo Carrier (ACC) are given. The objective of this economic analysis is to provide the National Aeronautics and Space Administration (NASA) with information on the economics of using the ACC on the Space Transportation System (STS). The detailed cost estimates for the ACC are presented by a work breakdown structure (WBS) to ensure that all elements of cost are considered in the economic analysis and related subsystem trades. Costs reported by WBS provide NASA with a basis for comparing competing designs and provide detailed cost information that can be used to forecast phase C/D planning for new projects or programs derived from preliminary conceptual design studies. The scope covers all STS and STS/ACC launch vehicle cost impacts for delivering payloads to a 160 NM low Earth orbit (LEO).

  2. A Prospective Pathologic Study to Define the Clinical Target Volume for Partial Breast Radiation Therapy in Women With Early Breast Cancer

    Energy Technology Data Exchange (ETDEWEB)

    Nguyen, Brandon T., E-mail: Brandon.Nguyen@act.gov.au [Department of Radiation Oncology, Peter MacCallum Cancer Centre, East Melbourne, Victoria (Australia); Canberra Hospital, Radiation Oncology Department, Garran, ACT (Australia); Deb, Siddhartha [Department of Anatomical Pathology, Peter MacCallum Cancer Centre, East Melbourne, Victoria (Australia); Victorian Cancer Biobank, Cancer Council of Victoria, Carlton, Victoria (Australia); Fox, Stephen [Department of Anatomical Pathology, Peter MacCallum Cancer Centre, East Melbourne, Victoria (Australia); Hill, Prudence [Department of Anatomical Pathology, St. Vincent' s Hospital Melbourne, Fitzroy, Victoria (Australia); Collins, Marnie [Centre for Biostatistics and Clinical Trials, Peter MacCallum Cancer Centre, East Melbourne, Victoria (Australia); Chua, Boon H. [Department of Radiation Oncology, Peter MacCallum Cancer Centre, East Melbourne, Victoria (Australia); University of Melbourne, Parkville, Victoria (Australia)

    2012-12-01

    Purpose: To determine an appropriate clinical target volume for partial breast radiation therapy (PBRT) based on the spatial distribution of residual invasive and in situ carcinoma after wide local excision (WLE) for early breast cancer or ductal carcinoma in situ (DCIS). Methods and Materials: We performed a prospective pathologic study of women potentially eligible for PBRT who had re-excision and/or completion mastectomy after WLE for early breast cancer or DCIS. A pathologic assessment protocol was used to determine the maximum radial extension (MRE) of residual carcinoma from the margin of the initial surgical cavity. Women were stratified by the closest initial radial margin width: negative (>1 mm), close (>0 mm and {<=}1 mm), or involved. Results: The study population was composed of 133 women with a median age of 59 years (range, 27-82 years) and the following stage groups: 0 (13.5%), I (40.6%), II (38.3%), and III (7.5%). The histologic subtypes of the primary tumor were invasive ductal carcinoma (74.4%), invasive lobular carcinoma (12.0%), and DCIS alone (13.5%). Residual carcinoma was present in the re-excision and completion mastectomy specimens in 55.4%, 14.3%, and 7.2% of women with an involved, close, and negative margin, respectively. In the 77 women with a noninvolved radial margin, the MRE of residual disease, if present, was {<=}10 mm in 97.4% (95% confidence interval 91.6-99.5) of cases. Larger MRE measurements were significantly associated with an involved margin (P<.001), tumor size >30 mm (P=.03), premenopausal status (P=.03), and negative progesterone receptor status (P=.05). Conclusions: A clinical target volume margin of 10 mm would encompass microscopic residual disease in >90% of women potentially eligible for PBRT after WLE with noninvolved resection margins.

  3. Dynamics of chest wall volume regulation during constant work rate exercise in patients with chronic obstructive pulmonary disease

    Energy Technology Data Exchange (ETDEWEB)

    Takara, L.S.; Cunha, T.M.; Barbosa, P.; Rodrigues, M.K.; Oliveira, M.F.; Nery, L.E. [Setor de Função Pulmonar e Fisiologia Clínica do Exercício, Disciplina de Pneumologia, Departamento de Medicina, Universidade Federal de São Paulo, São Paulo, SP (Brazil); Neder, J.A. [Setor de Função Pulmonar e Fisiologia Clínica do Exercício, Disciplina de Pneumologia, Departamento de Medicina, Universidade Federal de São Paulo, São Paulo, SP (Brazil); Division of Respiratory and Critical Care Medicine, Department of Medicine, Queen' s University, Kingston, ON (Canada)

    2012-10-15

    This study evaluated the dynamic behavior of total and compartmental chest wall volumes [(V{sub CW}) = rib cage (V{sub RC}) + abdomen (V{sub AB})] as measured breath-by-breath by optoelectronic plethysmography during constant-load exercise in patients with stable chronic obstructive pulmonary disease. Thirty males (GOLD stages II-III) underwent a cardiopulmonary exercise test to the limit of tolerance (Tlim) at 75% of peak work rate on an electronically braked cycle ergometer. Exercise-induced dynamic hyperinflation was considered to be present when end-expiratory (EE) V{sub CW} increased in relation to resting values. There was a noticeable heterogeneity in the patterns of V{sub CW} regulation as EEV{sub CW} increased non-linearly in 17/30 “hyperinflators” and decreased in 13/30 “non-hyperinflators” (P < 0.05). EEV{sub AB} decreased slightly in 8 of the “hyperinflators”, thereby reducing and slowing the rate of increase in end-inspiratory (EI) V{sub CW} (P < 0.05). In contrast, decreases in EEV{sub CW} in the “non-hyperinflators” were due to the combination of stable EEV{sub RC} with marked reductions in EEV{sub AB}. These patients showed lower EIV{sub CW} and end-exercise dyspnea scores but longer Tlim than their counterparts (P < 0.05). Dyspnea increased and Tlim decreased non-linearly with a faster rate of increase in EIV{sub CW} regardless of the presence or absence of dynamic hyperinflation (P < 0.001). However, no significant between-group differences were observed in metabolic, pulmonary gas exchange and cardiovascular responses to exercise. Chest wall volumes are continuously regulated during exercise in order to postpone (or even avoid) their migration to higher operating volumes in patients with COPD, a dynamic process that is strongly dependent on the behavior of the abdominal compartment.

  4. Dynamics of chest wall volume regulation during constant work rate exercise in patients with chronic obstructive pulmonary disease

    Directory of Open Access Journals (Sweden)

    L.S. Takara

    2012-12-01

    Full Text Available This study evaluated the dynamic behavior of total and compartmental chest wall volumes [(V CW = rib cage (V RC + abdomen (V AB] as measured breath-by-breath by optoelectronic plethysmography during constant-load exercise in patients with stable chronic obstructive pulmonary disease. Thirty males (GOLD stages II-III underwent a cardiopulmonary exercise test to the limit of tolerance (Tlim at 75% of peak work rate on an electronically braked cycle ergometer. Exercise-induced dynamic hyperinflation was considered to be present when end-expiratory (EE V CW increased in relation to resting values. There was a noticeable heterogeneity in the patterns of V CW regulation as EEV CW increased non-linearly in 17/30 "hyperinflators" and decreased in 13/30 "non-hyperinflators" (P < 0.05. EEV AB decreased slightly in 8 of the "hyperinflators", thereby reducing and slowing the rate of increase in end-inspiratory (EI V CW (P < 0.05. In contrast, decreases in EEV CW in the "non-hyperinflators" were due to the combination of stable EEV RC with marked reductions in EEV AB. These patients showed lower EIV CW and end-exercise dyspnea scores but longer Tlim than their counterparts (P < 0.05. Dyspnea increased and Tlim decreased non-linearly with a faster rate of increase in EIV CW regardless of the presence or absence of dynamic hyperinflation (P < 0.001. However, no significant between-group differences were observed in metabolic, pulmonary gas exchange and cardiovascular responses to exercise. Chest wall volumes are continuously regulated during exercise in order to postpone (or even avoid their migration to higher operating volumes in patients with COPD, a dynamic process that is strongly dependent on the behavior of the abdominal compartment.

  5. FDG-PET Response Prediction in Pediatric Hodgkin’s Lymphoma: Impact of Metabolically Defined Tumor Volumes and Individualized SUV Measurements on the Positive Predictive Value

    Energy Technology Data Exchange (ETDEWEB)

    Hussien, Amr Elsayed M. [Department of Nuclear Medicine (KME), Forschungszentrum Jülich, Medical Faculty, Heinrich-Heine-University Düsseldorf, Jülich, 52426 (Germany); Department of Nuclear Medicine, Medical Faculty, Heinrich-Heine-University Düsseldorf, Düsseldorf, 40225 (Germany); Furth, Christian [Department of Radiology and Nuclear Medicine, Medical School, Otto-von-Guericke University Magdeburg, Magdeburg, 39120 (Germany); Schönberger, Stefan [Department of Pediatric Oncology, Hematology and Clinical Immunology, University Children’s Hospital, Medical Faculty, Heinrich-Heine-University Düsseldorf, Düsseldorf, 40225 (Germany); Hundsdoerfer, Patrick [Department of Pediatric Oncology and Hematology, Charité Campus Virchow, Humboldt-University Berlin, Berlin, 13353 (Germany); Steffen, Ingo G.; Amthauer, Holger [Department of Radiology and Nuclear Medicine, Medical School, Otto-von-Guericke University Magdeburg, Magdeburg, 39120 (Germany); Müller, Hans-Wilhelm; Hautzel, Hubertus, E-mail: h.hautzel@fz-juelich.de [Department of Nuclear Medicine (KME), Forschungszentrum Jülich, Medical Faculty, Heinrich-Heine-University Düsseldorf, Jülich, 52426 (Germany); Department of Nuclear Medicine, Medical Faculty, Heinrich-Heine-University Düsseldorf, Düsseldorf, 40225 (Germany)

    2015-01-28

    Background: In pediatric Hodgkin’s lymphoma (pHL) early response-to-therapy prediction is metabolically assessed by (18)F-FDG PET carrying an excellent negative predictive value (NPV) but an impaired positive predictive value (PPV). Aim of this study was to improve the PPV while keeping the optimal NPV. A comparison of different PET data analyses was performed applying individualized standardized uptake values (SUV), PET-derived metabolic tumor volume (MTV) and the product of both parameters, termed total lesion glycolysis (TLG); Methods: One-hundred-eight PET datasets (PET1, n = 54; PET2, n = 54) of 54 children were analysed by visual and semi-quantitative means. SUVmax, SUVmean, MTV and TLG were obtained the results of both PETs and the relative change from PET1 to PET2 (Δ in %) were compared for their capability of identifying responders and non-responders using receiver operating characteristics (ROC)-curves. In consideration of individual variations in noise and contrasts levels all parameters were additionally obtained after threshold correction to lean body mass and background; Results: All semi-quantitative SUV estimates obtained at PET2 were significantly superior to the visual PET2 analysis. However, ΔSUVmax revealed the best results (area under the curve, 0.92; p < 0.001; sensitivity 100%; specificity 85.4%; PPV 46.2%; NPV 100%; accuracy, 87.0%) but was not significantly superior to SUVmax-estimation at PET2 and ΔTLGmax. Likewise, the lean body mass and background individualization of the datasets did not impove the results of the ROC analyses; Conclusions: Sophisticated semi-quantitative PET measures in early response assessment of pHL patients do not perform significantly better than the previously proposed ΔSUVmax. All analytical strategies failed to improve the impaired PPV to a clinically acceptable level while preserving the excellent NPV.

  6. FDG-PET Response Prediction in Pediatric Hodgkin’s Lymphoma: Impact of Metabolically Defined Tumor Volumes and Individualized SUV Measurements on the Positive Predictive Value

    Directory of Open Access Journals (Sweden)

    Amr Elsayed M. Hussien

    2015-01-01

    Full Text Available Background: In pediatric Hodgkin’s lymphoma (pHL early response-to-therapy prediction is metabolically assessed by (18F-FDG PET carrying an excellent negative predictive value (NPV but an impaired positive predictive value (PPV. Aim of this study was to improve the PPV while keeping the optimal NPV. A comparison of different PET data analyses was performed applying individualized standardized uptake values (SUV, PET-derived metabolic tumor volume (MTV and the product of both parameters, termed total lesion glycolysis (TLG; Methods: One-hundred-eight PET datasets (PET1, n = 54; PET2, n = 54 of 54 children were analysed by visual and semi-quantitative means. SUVmax, SUVmean, MTV and TLG were obtained the results of both PETs and the relative change from PET1 to PET2 (Δ in % were compared for their capability of identifying responders and non-responders using receiver operating characteristics (ROC-curves. In consideration of individual variations in noise and contrasts levels all parameters were additionally obtained after threshold correction to lean body mass and background; Results: All semi-quantitative SUV estimates obtained at PET2 were significantly superior to the visual PET2 analysis. However, ΔSUVmax revealed the best results (area under the curve, 0.92; p < 0.001; sensitivity 100%; specificity 85.4%; PPV 46.2%; NPV 100%; accuracy, 87.0% but was not significantly superior to SUVmax-estimation at PET2 and ΔTLGmax. Likewise, the lean body mass and background individualization of the datasets did not impove the results of the ROC analyses; Conclusions: Sophisticated semi-quantitative PET measures in early response assessment of pHL patients do not perform significantly better than the previously proposed ΔSUVmax. All analytical strategies failed to improve the impaired PPV to a clinically acceptable level while preserving the excellent NPV.

  7. Defining Dyslexia

    Science.gov (United States)

    Tunmer, William; Greaney, Keith

    2010-01-01

    In 2007, the New Zealand Ministry of Education formally recognized the condition of dyslexia for the first time and has subsequently developed a working definition of the condition. The aim of this article is to draw on contemporary theory and research on reading development, reading difficulties, and reading intervention to describe what the…

  8. Phase II Trial of Radiosurgery to Magnetic Resonance Spectroscopy-Defined High-Risk Tumor Volumes in Patients With Glioblastoma Multiforme

    Energy Technology Data Exchange (ETDEWEB)

    Einstein, Douglas B., E-mail: douglas.einstein@khnetwork.org [Department of Radiation Oncology, Case Comprehensive Cancer Center, Case Western Reserve University Kettering, Ohio (United States); Wessels, Barry [Department of Radiation Oncology, Case Comprehensive Cancer Center, Case Western Reserve University Kettering, Ohio (United States); Bangert, Barbara [Department of Radiology, Case Comprehensive Cancer Center, Case Western Reserve University Kettering, Ohio (United States); Fu, Pingfu [Department of Biostatistics, Case Comprehensive Cancer Center, Case Western Reserve University Kettering, Ohio (United States); Nelson, A. Dennis [Department of Radiology, Case Comprehensive Cancer Center, Case Western Reserve University Kettering, Ohio (United States); Cohen, Mark [Department of Pathology, Case Comprehensive Cancer Center, Case Western Reserve University Kettering, Ohio (United States); Sagar, Stephen [Department of Neurology, Case Comprehensive Cancer Center, Case Western Reserve University Kettering, Ohio (United States); Lewin, Jonathan [Department of Radiology, Case Comprehensive Cancer Center, Case Western Reserve University Kettering, Ohio (United States); Sloan, Andrew [Department of Neurosurgery, Case Comprehensive Cancer Center, Case Western Reserve University Kettering, Ohio (United States); Zheng Yiran; Williams, Jordonna; Colussi, Valdir; Vinkler, Robert [Department of Radiation Oncology, Case Comprehensive Cancer Center, Case Western Reserve University Kettering, Ohio (United States); Maciunas, Robert [Department of Neurosurgery, Case Comprehensive Cancer Center, Case Western Reserve University Kettering, Ohio (United States)

    2012-11-01

    Purpose: To determine the efficacy of a Gamma Knife stereotactic radiosurgery (SRS) boost to areas of high risk determined by magnetic resonance spectroscopy (MRS) functional imaging in addition to standard radiotherapy for patients with glioblastoma (GBM). Methods and Materials: Thirty-five patients in this prospective Phase II trial underwent surgical resection or biopsy for a GBM followed by SRS directed toward areas of MRS-determined high biological activity within 2 cm of the postoperative enhancing surgical bed. The MRS regions were determined by identifying those voxels within the postoperative T2 magnetic resonance imaging volume that contained an elevated choline/N-acetylaspartate ratio in excess of 2:1. These voxels were marked, digitally fused with the SRS planning magnetic resonance image, targeted with an 8-mm isocenter per voxel, and treated using Radiation Therapy Oncology Group SRS dose guidelines. All patients then received conformal radiotherapy to a total dose of 60 Gy in 2-Gy daily fractions. The primary endpoint was overall survival. Results: The median survival for the entire cohort was 15.8 months. With 75% of recursive partitioning analysis (RPA) Class 3 patients still alive 18 months after treatment, the median survival for RPA Class 3 has not yet been reached. The median survivals for RPA Class 4, 5, and 6 patients were 18.7, 12.5, and 3.9 months, respectively, compared with Radiation Therapy Oncology Group radiotherapy-alone historical control survivals of 11.1, 8.9, and 4.6 months. For the 16 of 35 patients who received concurrent temozolomide in addition to protocol radiotherapeutic treatment, the median survival was 20.8 months, compared with European Organization for Research and Treatment of Cancer historical controls of 14.6 months using radiotherapy and temozolomide. Grade 3/4 toxicities possibly attributable to treatment were 11%. Conclusions: This represents the first prospective trial using selective MRS-targeted functional SRS

  9. Genetic correlations between brain volumes and the WAIS-III dimensions of verbal comprehension, working memory, perceptual organization, and processing speed

    DEFF Research Database (Denmark)

    Posthuma, Daniëlle; Baare, Wim F.C.; Hulshoff Pol, Hilleke E.

    2003-01-01

    We recently showed that the correlation of gray and white matter volume with full scale IQ and the Working Memory dimension are completely mediated by common genetic factors (Posthuma et al., 2002). Here we examine whether the other WAIS III dimensions (Verbal Comprehension, Perceptual Organization...... to Working Memory capacity (r = 0.27). This phenotypic correlation is completely due to a common underlying genetic factor. Processing Speed was genetically related to white matter volume (r(g) = 0.39). Perceptual Organization was both genetically (r(g) = 0.39) and environmentally (r(e) = -0.71) related...

  10. Work, health and wellbeing The challenges of managing health at work

    CERN Document Server

    Vickerstaff, Sarah; Wilkie, Ross

    2011-01-01

    This multi-disciplinary volume brings together original research from diverse disciplinary backgrounds investigating how we can define and operationalise a bio-psychosocial model of ill-health to improve work participation in middle and later life.

  11. Working to define professionalism in pediatric anesthesiology: a qualitative study of domains of the expert pediatric anesthesiologist as valued by interdisciplinary stakeholders.

    Science.gov (United States)

    Lockman, Justin L; Schwartz, Alan Jay; Cronholm, Peter F

    2017-02-01

    Unprofessional behavior is a significant problem throughout graduate medical education programs and medical centers. Some authors have suggested that professionalism curricula should be focused toward faculty, not trainees, to interrupt the modeling of unprofessionalism. Developing such curricula requires a needs assessment and is challenging given data indicating that the definition of professionalism varies based on medical specialty. Thus, a specialty-specific definition of professionalism is needed as a first step in any curriculum development. The aim of this study was to define professionalism in pediatric anesthesiology. This is a qualitative study using focus groups for data collection and a grounded theory approach for analysis. Four relevant stakeholder groups, pediatric surgeons and endoscopists, perioperative nurses, pediatric anesthesiologists, and parents of children who had undergone surgery at our facility, were recruited for participation. De-identified transcripts were analyzed and coded to derive major domains and component themes relevant to the definition of professionalism for pediatric anesthesiology. Member checking with participants from our stakeholder groups was used to validate thematic development and increase the trustworthiness of our findings. Focus group participants included 20 individuals, 14 of whom were female. Analysis of transcripts identified 11 major domains across the four groups: Patient Ownership, Specialty Expertise, Continuous Team Improvement, Expressive Communication, Active Listening, Care Coordination, Medical Hierarchy, Leadership, Teamwork, Personality Traits, and Physical Image. The data uncovered several controversies for future study. A composite of these 11 domains may give a more complete image of what surgical and nursing colleagues, patient families, and anesthesiologist partners expect of the pediatric anesthesiologist. Despite some overlap and interdependence between domains, this research may contribute

  12. Issues in defining and measuring veteran community reintegration: Proceedings of the Working Group on Community Reintegration, VA Rehabilitation Outcomes Conference, Miami, Florida

    Directory of Open Access Journals (Sweden)

    Linda Resnik, PT, PhD

    2012-02-01

    Full Text Available In January 2010, the Department of Veterans Affairs (VA Rehabilitation Research and Development Service convened a State of the Art (SOTA conference to advance the field of outcome measurement for rehabilitation-related studies. This article reports on the proceedings of the SOTA Working Group on Community Reintegration. We explored the use of the International Classification of Health, Disability, and Functioning as a theoretical framework for measuring community reintegration; identified key dimensions of community reintegration that could and/or should be measured; discussed challenges in measuring community reintegration; suggested steps to enhance community reintegration measurement; proposed future research that focuses on outcomes measures for community reintegration and the study of community reintegration outcomes; and made policy recommendations that would facilitate community reintegration research within the VA.

  13. Issues in defining and measuring veteran community reintegration: proceedings of the Working Group on Community Reintegration, VA Rehabilitation Outcomes Conference, Miami, Florida.

    Science.gov (United States)

    Resnik, Linda; Bradford, Daniel W; Glynn, Shirley M; Jette, Alan M; Johnson Hernandez, Caitlin; Wills, Sharon

    2012-01-01

    In January 2010, the Department of Veterans Affairs (VA) Rehabilitation Research and Development Service convened a State of the Art (SOTA) conference to advance the field of outcome measurement for rehabilitation-related studies. This article reports on the proceedings of the SOTA Working Group on Community Reintegration. We explored the use of the International Classification of Health, Disability, and Functioning as a theoretical framework for measuring community reintegration; identified key dimensions of community reintegration that could and/or should be measured; discussed challenges in measuring community reintegration; suggested steps to enhance community reintegration measurement; proposed future research that focuses on outcomes measures for community reintegration and the study of community reintegration outcomes; and made policy recommendations that would facilitate community reintegration research within the VA.

  14. A four-part working bibliography of neuroethics: part 1: overview and reviews – defining and describing the field and its practices

    Science.gov (United States)

    2014-01-01

    Background Neuroethics entails investigations of neurocognitive mechanisms of morality and ethics; and studies and address of the ethical issues spawned by the use of neuroscience and its technologies to investigate cognition, emotion and actions. These two principal emphases, or what have been called “traditions” of neuroethics both mirror traditional bioethical discussions (such as debates about the safety of technological and pharmaceutical advances and ethical implications of new scientific and technological discoveries), and engage discourse about neuroscientific investigations of (proto-moral and moral) cognition, emotions and behaviors, and what such findings may mean for human beliefs and conduct - from the individual to the political levels. Given the growth, range, and rapid maturation of the field of neuroethics we provide an iterative, four-part document that affords a repository of international papers, books, and chapters that address the field in overview, and present discussion(s) of more particular aspects and topics of neuroethics. This first installment lists reviews and overviews of the discipline, and broad summaries of basic developments and issues of the field. Methods To systematically survey the neuroethics literature, searches were performed by accessing 11 databases, 8 additional literature depositories, and 4 individual journal searches using indexing language for National Library of Medicine (NLM) Medical Subject Heading databases. Searches and assurance against overlapping coverage were conducted using the RefWorks citation management program. Results Overview, review and reflections upon the history and multicultural perspectives of neuroethics were obtained and relevant listings from international journals, books, and book chapters are provided. Part I will be followed by three installments that will address a): the neuroscience of morality and ethics, including discussions of free will, and personal autonomy; b)

  15. Defining Service Coordination: A Social Work Perspective.

    Science.gov (United States)

    Bunger, Alicia C

    2010-10-01

    To address fragmentation, social workers are encouraged to "coordinate." This pilot study explores the meaning of, and factors that facilitate or prevent "coordination" and is intended as a first step toward future conceptual refinement, theory development, and system interventions. Using data from treatment guidelines archived by the National Guideline Clearinghouse (n=9) and semi-structured interviews with social workers (n=4), themes related to the definition, indicators, and perceptions of coordination were explored using a grounded theory approach. Data suggest the need for coordination is driven by complex client needs, but the quality of providers' personal relationships influence coordination. Future research might examine the impact of standardization of roles, referral procedures, and treatment philosophies.

  16. Definición del objeto de trabajo y conceptualización de los Sistemas de Información Audiovisual de la Televisión Defining the object of work and conceptualizing TV Audiovisual Information Systems

    Directory of Open Access Journals (Sweden)

    Inés-Carmen Póveda-López

    2010-04-01

    Full Text Available Se define el objeto de trabajo documental en los sistemas de información audiovisual de la televisión, partiendo de las distintas definiciones aportadas por los principales autores e instituciones sobre los conceptos de audiovisual, imagen en movimiento, sonido, documentación audiovisual, información audiovisual y documento audiovisual. Se llega así, por medio de la cuantificación y el análisis de las ideas y conceptos más repetidos en las definiciones analizadas, a definir un "Documento televisivo de imagen en movimiento".The object of documentary work in visual information systems on TV is defined on the basis of the various ideas provided by leading authors and institutions about the concepts of audiovisual, moving image, sound, audiovisual documentation, audiovisual information and audiovisual document. This takes us through quantification and analysis of the most recurrent ideas and concepts discussed in the studied definitions.

  17. Children and adults minimise activated muscle volume by selecting gait parameters that balance gross mechanical power and work demands.

    Science.gov (United States)

    Hubel, Tatjana Y; Usherwood, James R

    2015-09-01

    Terrestrial locomotion on legs is energetically expensive. Compared with cycling, or with locomotion in swimming or flying animals, walking and running are highly uneconomical. Legged gaits that minimise mechanical work have previously been identified and broadly match walking and running at appropriate speeds. Furthermore, the 'cost of muscle force' approaches are effective in relating locomotion kinetics to metabolic cost. However, few accounts have been made for why animals deviate from either work-minimising or muscle-force-minimising strategies. Also, there is no current mechanistic account for the scaling of locomotion kinetics with animal size and speed. Here, we report measurements of ground reaction forces in walking children and adult humans, and their stance durations during running. We find that many aspects of gait kinetics and kinematics scale with speed and size in a manner that is consistent with minimising muscle activation required for the more demanding between mechanical work and power: spreading the duration of muscle action reduces activation requirements for power, at the cost of greater work demands. Mechanical work is relatively more demanding for larger bipeds--adult humans--accounting for their symmetrical M-shaped vertical force traces in walking, and relatively brief stance durations in running compared with smaller bipeds--children. The gaits of small children, and the greater deviation of their mechanics from work-minimising strategies, may be understood as appropriate for their scale, not merely as immature, incompletely developed and energetically sub-optimal versions of adult gaits.

  18. Déficit de volume de líquidos: perfil de características definidoras no paciente portador de queimadura Déficit de volumen de líquidos: perfil de características que la definen en pacientes portadores de quemaduras Fluidvolume deficit: profile of defining charateristics in burnt patients

    Directory of Open Access Journals (Sweden)

    Lídia Aparecida Rossi

    1998-07-01

    Full Text Available O objetivo deste estudo foi descrever o perfil das características definidoras do paciente com diagnóstico de enfermagem "Déficit de volume de líquidos" relacionado a perda ativa de líquidos, secundária à queimadura. Os dados foram coletados através de um instrumento, contendo 29 características definidoras possíveis para esse diagnóstico, aplicado a sete enfermeiros, que trabalhavam há pelo menos cinco anos em serviços especializados em tratamento de queimaduras. Os enfermeiros avaliaram as características definidoras, quanto ao grau que cada uma é indicativa desse diagnóstico, atribuindo valores numa escala de zero a um. Os resultados confirmaram todas as características definidoras apresentadas pela North American Nursing Diagnosis Association (NANDA, exceto uma (temperatura corporal elevada, e apontaram 10 novas características.El objetivo de este estudio fue describir el perfil de las características que la definen en paciente con diagnóstico de enfermería "Déficit de volumen de líquidos" relacionado a la pérdida activa de líquidos, secundaria a quemadura. La recolección de datos fue hecha a través de un instrumento que conttene 29 características posibiles que definen ese diagnóstico. El instrumento fue desarrollado con siete enfermeros que trabajaban en una Unidad de Quemados, los quales poseían una experiencia mínima de cinco años. Los enfermeros evaluaron las características en cuanto al grado que cada una de estas características eran indicativas de ese diagnóstico, atribuyendo valores en una escala de zero a uno. Los resultados confirmaron todas las características presentadas por NANDA para ese diagnóstico, excepto una (temperatura corporal elevada y indicaron 10 nuevas características.The present study aimed at describing the profile of defining characteristics in patients with the nursing diagnosis "Fluid volume deficit" related to active loss of fluid secondary to burns. Data were collected by

  19. Impact of 18-fluorodeoxyglucose positron emission tomography on computed tomography defined target volumes in radiation treatment planning of esophageal cancer : reduction in geographic misses with equal inter-observer variability

    NARCIS (Netherlands)

    Schreurs, Liesbeth; Busz, D. M.; Paardekooper, G. M. R. M.; Beukema, J. C.; Jager, P. L.; Van der Jagt, E. J.; van Dam, G. M.; Groen, H.; Plukker, J. Th. M.; Langendijk, J. A.

    2010-01-01

    P>Target volume definition in modern radiotherapy is based on planning computed tomography (CT). So far, 18-fluorodeoxyglucose positron emission tomography (FDG-PET) has not been included in planning modality in volume definition of esophageal cancer. This study evaluates fusion of FDG-PET and CT in

  20. Manned remote work station development article. Volume 1, book 1: Flight article requirements. Appendix A: Mission requirements

    Science.gov (United States)

    1979-01-01

    The requirements for several configurations of flight articles are presented. These requirements provide the basis to design manned remote work station development test articles and establish tests and simulation objectives for the resolution of development issues. Mission system and subsystem requirements for four MRWS configurations included: open cherry picker; closed cherry picker; crane turret; and free flyer.

  1. Identificação das características definidoras do diagnóstico de enfermagem excesso de volume de líquidos Identificación de las caracteristicas definidoras del diagnóstico de enfermería excesso de volumen de liquidos Identification od defining characteristics of the nursing diagnosis fluid volume excess

    Directory of Open Access Journals (Sweden)

    Heloísa Cristina Quatrini Carvalho Passos Guimarães

    2000-04-01

    Full Text Available Este estudo foi realizado com o objetivo de identificar as características definidoras do diagnóstico de enfermagem Excesso de Volume de Líquidos, proposto pela NANDA. Os dados foram coletados num hospital especializado em cardiologia, com uma amostra de 29 pacientes, cuja seleção foi realizada por duas enfermeiras peritas no assunto. Concluiu-se que houve concordância das duas peritas na identificação de nove pacientes com o diagnóstico em estudo e 20 sem o diagnóstico. As características definidoras identificadas aparecem em percentagens diferentes nos pacientes estudados.Este estudio fue llevado a cabo con el objetivo de validar el diagnóstico de enfermería "Exceso de Volumen de Líquidos". Para esto se buscó verificar la existencia o no de concordancia entre enfermeras de un hospital especializado en cardiología en lo que respecta a la identificación de las características definitorias utilizadas para determinar dicho diagnóstico, tal como es propuesto por la Asociación Norteamericana de Diagnósticos de Enfermería. El estudio fue realizado con 29 pacientes evaluados, en un primer momento, por dos enfermeras especialistas. Los resultados mostraron que las dos enfermeras concordaron en la indicación de presencia del diagnóstico objeto de estudio, en 9 pacientes y de ausencia en 20. Las características definitorias que determinaban la presencia o ausencia del diagnóstico se presentaron en diferentes porcentajes en los pacientes estudiados.This study aimed at verifying the defining characteristics of the nursing diagnosis "Fluid Volume Excess" proposed by NANDA. Data collection was carried out within a specialized Cardiology health care setting where the 29 patients were selected by two expert nurses. The conclusion showed consonance of opinions between the two professionals in regard to the identification of nine patients with diagnosis and 20 without this type of diagnosis. The identified defining characteristics

  2. DACC program cost and work breakdown structure-dictionary. General purpose aft cargo carrier study, volume 2

    Science.gov (United States)

    1985-01-01

    Results of detailed cost estimates and economic analysis performed on the updated 201 configuration of the dedicated Aft Cargo Carrier (DACC) are given. The objective of this economic analysis is to provide the National Aeronautics and Space Administration (NASA) with information on the economics of using the DACC on the Space Transportation System (STS). The detailed cost estimates for the DACC are presented by a work breakdown structure (WBS) to ensure that all elements of cost are considered in the economic analysis and related subsystem trades. Costs reported by WBS provide NASA with a basis for comparing competing designs and provide detailed cost information that can be used to forecast phase C/D planning for new projects or programs derived from preliminary conceptual design studies. The scope covers all STS and STS/DACC launch vehicle cost impacts for delivering an orbital transfer vehicle to a 120 NM low Earth orbit (LEO).

  3. Defining and testing a granular continuum element

    Energy Technology Data Exchange (ETDEWEB)

    Rycroft, Chris H.; Kamrin, Ken; Bazant, Martin Z.

    2007-12-03

    Continuum mechanics relies on the fundamental notion of amesoscopic volume "element" in which properties averaged over discreteparticles obey deterministic relationships. Recent work on granularmaterials suggests a continuum law may be inapplicable, revealinginhomogeneities at the particle level, such as force chains and slow cagebreaking. Here, we analyze large-scale Discrete-Element Method (DEM)simulations of different granular flows and show that a "granularelement" can indeed be defined at the scale of dynamical correlations,roughly three to five particle diameters. Its rheology is rather subtle,combining liquid-like dependence on deformation rate and solid-likedependence on strain. Our results confirm some aspects of classicalplasticity theory (e.g., coaxiality of stress and deformation rate),while contradicting others (i.e., incipient yield), and can guide thedevelopment of more realistic continuum models.

  4. The relationship of the emotional climate of work and threat to patient outcome in a high-volume thoracic surgery operating room team.

    Science.gov (United States)

    Nurok, Michael; Evans, Linda A; Lipsitz, Stuart; Satwicz, Paul; Kelly, Andrea; Frankel, Allan

    2011-03-01

    It is widely believed that the emotional climate of surgical team's work may affect patient outcome. To analyse the relationship between the emotional climate of work and indices of threat to patient outcome. Interventional study. Operating rooms in a high-volume thoracic surgery centre from September 2007 to June 2008. Thoracic surgery operating room teams. Two 90 min team-skills training sessions focused on findings from a standardised safety-culture survey administered to all participants and highlighting positive and problematic aspects of team skills, communication and leadership. Relationship of functional or less functional emotional climates of work to indices of threat to patient outcome. A less functional emotional climate corresponded to more threat to outcome in the sterile surgical environment in the pre-intervention period (pwork in the sterile surgical environment appeared to be related to threat to patient outcome prior to, but not after, a team-training intervention. Further study of the relationship between the emotional climate of work and threat to patient outcome using reproducible methods is required.

  5. Orbital transfer vehicle concept definition and system analysis study, 1985. Volume 5: Work breakdown structure and dictionary

    Science.gov (United States)

    Nelson, James H.; Callan, Daniel R.

    1985-01-01

    To establish consistency and visibility within the Orbital Transfer Vehicle (OTV) program, a preliminary work breakdown structure (WBS) and dictionary were developed. The dictionary contains definitions of terms to be used in conjunction with the WBS so that a clear understanding of the content of the hardware, function, and cost elements may be established. The OTV WBS matrix is a two-dimensional structure which shows the interrelationship of these dimensions: the hardware elements dimension and the phase and function dimension. The dimension of time cannot be shown graphically, but must be considered. Each cost entry varies with time so that it is necessary to know these cost values by year for budget planning and approval as well as for establishing cost streams for discounting purposes in the economic analysis. While a multiple dimensional approach may at first appear complex, it actually provides benefits which outweigh any concern. This structural interrelationship provides the capability to view and analyze the OTV costs from a number of different financial and management aspects. Cost may be summed by hardware groupings, phases, or functions. The WBS may be used in a number of dimensional or single listing format applications.

  6. Defining a roadmap for harmonizing quality indicators in Laboratory Medicine: a consensus statement on behalf of the IFCC Working Group "Laboratory Error and Patient Safety" and EFLM Task and Finish Group "Performance specifications for the extra-analytical phases".

    Science.gov (United States)

    Sciacovelli, Laura; Panteghini, Mauro; Lippi, Giuseppe; Sumarac, Zorica; Cadamuro, Janne; Galoro, César Alex De Olivera; Pino Castro, Isabel Garcia Del; Shcolnik, Wilson; Plebani, Mario

    2017-08-28

    The improving quality of laboratory testing requires a deep understanding of the many vulnerable steps involved in the total examination process (TEP), along with the identification of a hierarchy of risks and challenges that need to be addressed. From this perspective, the Working Group "Laboratory Errors and Patient Safety" (WG-LEPS) of International Federation of Clinical Chemistry and Laboratory Medicine (IFCC) is focusing its activity on implementation of an efficient tool for obtaining meaningful information on the risk of errors developing throughout the TEP, and for establishing reliable information about error frequencies and their distribution. More recently, the European Federation of Clinical Chemistry and Laboratory Medicine (EFLM) has created the Task and Finish Group "Performance specifications for the extra-analytical phases" (TFG-PSEP) for defining performance specifications for extra-analytical phases. Both the IFCC and EFLM groups are working to provide laboratories with a system to evaluate their performances and recognize the critical aspects where improvement actions are needed. A Consensus Conference was organized in Padova, Italy, in 2016 in order to bring together all the experts and interested parties to achieve a consensus for effective harmonization of quality indicators (QIs). A general agreement was achieved and the main outcomes have been the release of a new version of model of quality indicators (MQI), the approval of a criterion for establishing performance specifications and the definition of the type of information that should be provided within the report to the clinical laboratories participating to the QIs project.

  7. International Society of Urological Pathology (ISUP) Consensus Conference on Handling and Staging of Radical Prostatectomy Specimens. Working group 2: T2 substaging and prostate cancer volume.

    Science.gov (United States)

    van der Kwast, Theo H; Amin, Mahul B; Billis, Athanase; Epstein, Jonathan I; Griffiths, David; Humphrey, Peter A; Montironi, Rodolfo; Wheeler, Thomas M; Srigley, John R; Egevad, Lars; Delahunt, Brett

    2011-01-01

    The 2009 International Society of Urological Pathology consensus conference in Boston made recommendations regarding the standardization of pathology reporting of radical prostatectomy specimens. Issues relating to the substaging of pT2 prostate cancers according to the TNM 2002/2010 system, reporting of tumor size/volume and zonal location of prostate cancers were coordinated by working group 2. A survey circulated before the consensus conference demonstrated that 74% of the 157 participants considered pT2 substaging of prostate cancer to be of clinical and/or academic relevance. The survey also revealed a considerable variation in the frequency of reporting of pT2b substage prostate cancer, which was likely a consequence of the variable methodologies used to distinguish pT2a from pT2b tumors. Overview of the literature indicates that current pT2 substaging criteria lack clinical relevance and the majority (65.5%) of conference attendees wished to discontinue pT2 substaging. Therefore, the consensus was that reporting of pT2 substages should, at present, be optional. Several studies have shown that prostate cancer volume is significantly correlated with other clinicopathological features, including Gleason score and extraprostatic extension of tumor; however, most studies fail to demonstrate this to have prognostic significance on multivariate analysis. Consensus was reached with regard to the reporting of some quantitative measure of the volume of tumor in a prostatectomy specimen, without prescribing a specific methodology. Incorporation of the zonal and/or anterior location of the dominant/index tumor in the pathology report was accepted by most participants, but a formal definition of the identifying features of the dominant/index tumor remained undecided.

  8. Definable deduction relation

    Institute of Scientific and Technical Information of China (English)

    张玉平

    1999-01-01

    The nonmonotonic deduction relation in default reasoning is defined with fixed point style, which has the many-extension property that classical logic is not possessed of. These two kinds of deductions both have boolean definability property, that is, their extensions or deductive closures can be defined by boolean formulas. A generalized form of fixed point method is employed to define a class of deduction relations, which all have the above property. Theorems on definability and atomless boolean algebras in model theory are essential in dealing with this assertion.

  9. On defining dietary fibre.

    Science.gov (United States)

    DeVries, Jonathan W

    2003-02-01

    Establishing a definition for dietary fibre has historically been a balance between nutrition knowledge and analytical method capabilities. While the most widely accepted physiologically-based definitions have generally been accurate in defining the dietary fibre in foods, scientists and regulators have tended, in practice, to rely on analytical procedures as the definitional basis in fact. As a result, incongruities between theory and practice have resulted in confusion regarding the components that make up dietary fibre. In November 1998 the president of the American Association of Cereal Chemists (AACC) appointed an expert scientific review committee and charged it with the task of reviewing and, if necessary, updating the definition of dietary fibre. The committee was further charged with assessing the state of analytical methodology and making recommendations relevant to the updated definition. After due deliberation, an updated definition of dietary fibre was delivered to the AACC Board of Directors for consideration and adoption (Anon, 2000; Jones 2000b). The updated definition includes the same food components as the historical working definition used for approximately 30 years (a very important point, considering that the majority of the research of the past 30 years delineating the positive health effects of dietary fibre is based on that working definition). However, the updated definition more clearly delineates the make-up of dietary fibre and its physiological functionality. As a result, relatively few changes will be necessary in analytical methodology. Current methodologies, in particular AACC-approved method of analysis 32-05 (Grami, 2000), Association of Official Analytical Chemists' official method of analysis 985.29 (Horwitz, 2000a) or AACC 32-07 (Grami, 2000) Association of Official Analytical Chemists 991.43 (Horwitz, 2000a) will continue to be sufficient and used for most foods. A small number of additional methods will be necessary to

  10. Historically defined autobiographical periods

    DEFF Research Database (Denmark)

    Brown, Norman R.; Hansen, Tia G. B.; Lee, Peter J.;

    2012-01-01

    The chapter reviews a research programme that has demonstrated the existence of historically defined autobiographical periods and identified the conditions that bring them about. Data from four samples of World War II-generation adults show that historically defined autobiographical periods endure...... over time and theoretical implications are discussed, notably by introducing a new approach to autobiographical memory, Transition Theory, which assumes that autobiographical memory is organized by transitional events that can be selfinitiated or externally imposed - historically defined...

  11. The volume of a soliton

    Energy Technology Data Exchange (ETDEWEB)

    Adam, C., E-mail: adam@fpaxp1.usc.es [Departamento de Física de Partículas, Universidad de Santiago de Compostela and Instituto Galego de Física de Altas Enerxias (IGFAE), E-15782 Santiago de Compostela (Spain); Haberichter, M. [School of Mathematics, Statistics and Actuarial Science, University of Kent, Canterbury, CT2 7NF (United Kingdom); Wereszczynski, A. [Institute of Physics, Jagiellonian University, Lojasiewicza 11, Kraków (Poland)

    2016-03-10

    There exists, in general, no unique definition of the size (volume, area, etc., depending on dimension) of a soliton. Here we demonstrate that the geometric volume (area etc.) of a soliton is singled out in the sense that it exactly coincides with the thermodynamical or continuum-mechanical volume. In addition, this volume may be defined uniquely for rather arbitrary solitons in arbitrary dimensions.

  12. Defining Life: Synthesis and Conclusions

    Science.gov (United States)

    Gayon, Jean

    2010-04-01

    The first part of the paper offers philosophical landmarks on the general issue of defining life. §1 defends that the recognition of “life” has always been and remains primarily an intuitive process, for the scientist as for the layperson. However we should not expect, then, to be able to draw a definition from this original experience, because our cognitive apparatus has not been primarily designed for this. §2 is about definitions in general. Two kinds of definition should be carefully distinguished: lexical definitions (based upon current uses of a word), and stipulative or legislative definitions, which deliberately assign a meaning to a word, for the purpose of clarifying scientific or philosophical arguments. The present volume provides examples of these two kinds of definitions. §3 examines three traditional philosophical definitions of life, all of which have been elaborated prior to the emergence of biology as a specific scientific discipline: life as animation (Aristotle), life as mechanism, and life as organization (Kant). All three concepts constitute a common heritage that structures in depth a good deal of our cultural intuitions and vocabulary any time we try to think about “life”. The present volume offers examples of these three concepts in contemporary scientific discourse. The second part of the paper proposes a synthesis of the major debates developed in this volume. Three major questions have been discussed. A first issue (§4) is whether we should define life or not, and why. Most authors are skeptical about the possibility of defining life in a strong way, although all admit that criteria are useful in contexts such as exobiology, artificial life and the origins of life. §5 examines the possible kinds of definitions of life presented in the volume. Those authors who have explicitly defended that a definition of life is needed, can be classified into two categories. The first category (or standard view) refers to two conditions

  13. Defining life: synthesis and conclusions.

    Science.gov (United States)

    Gayon, Jean

    2010-04-01

    The first part of the paper offers philosophical landmarks on the general issue of defining life. Section 1 defends that the recognition of "life" has always been and remains primarily an intuitive process, for the scientist as for the layperson. However we should not expect, then, to be able to draw a definition from this original experience, because our cognitive apparatus has not been primarily designed for this. Section 2 is about definitions in general. Two kinds of definition should be carefully distinguished: lexical definitions (based upon current uses of a word), and stipulative or legislative definitions, which deliberately assign a meaning to a word, for the purpose of clarifying scientific or philosophical arguments. The present volume provides examples of these two kinds of definitions. Section 3 examines three traditional philosophical definitions of life, all of which have been elaborated prior to the emergence of biology as a specific scientific discipline: life as animation (Aristotle), life as mechanism, and life as organization (Kant). All three concepts constitute a common heritage that structures in depth a good deal of our cultural intuitions and vocabulary any time we try to think about "life". The present volume offers examples of these three concepts in contemporary scientific discourse. The second part of the paper proposes a synthesis of the major debates developed in this volume. Three major questions have been discussed. A first issue (Section 4) is whether we should define life or not, and why. Most authors are skeptical about the possibility of defining life in a strong way, although all admit that criteria are useful in contexts such as exobiology, artificial life and the origins of life. Section 5 examines the possible kinds of definitions of life presented in the volume. Those authors who have explicitly defended that a definition of life is needed, can be classified into two categories. The first category (or standard view) refers

  14. Renormalized Volume

    Science.gov (United States)

    Gover, A. Rod; Waldron, Andrew

    2017-09-01

    We develop a universal distributional calculus for regulated volumes of metrics that are suitably singular along hypersurfaces. When the hypersurface is a conformal infinity we give simple integrated distribution expressions for the divergences and anomaly of the regulated volume functional valid for any choice of regulator. For closed hypersurfaces or conformally compact geometries, methods from a previously developed boundary calculus for conformally compact manifolds can be applied to give explicit holographic formulæ for the divergences and anomaly expressed as hypersurface integrals over local quantities (the method also extends to non-closed hypersurfaces). The resulting anomaly does not depend on any particular choice of regulator, while the regulator dependence of the divergences is precisely captured by these formulæ. Conformal hypersurface invariants can be studied by demanding that the singular metric obey, smoothly and formally to a suitable order, a Yamabe type problem with boundary data along the conformal infinity. We prove that the volume anomaly for these singular Yamabe solutions is a conformally invariant integral of a local Q-curvature that generalizes the Branson Q-curvature by including data of the embedding. In each dimension this canonically defines a higher dimensional generalization of the Willmore energy/rigid string action. Recently, Graham proved that the first variation of the volume anomaly recovers the density obstructing smooth solutions to this singular Yamabe problem; we give a new proof of this result employing our boundary calculus. Physical applications of our results include studies of quantum corrections to entanglement entropies.

  15. Defining Legal Moralism

    DEFF Research Database (Denmark)

    Thaysen, Jens Damgaard

    2015-01-01

    This paper discusses how legal moralism should be defined. It is argued that legal moralism should be defined as the position that “For any X, it is always a pro tanto reason for justifiably imposing legal regulation on X that X is morally wrong (where “morally wrong” is not conceptually equivalent...

  16. Modular Software-Defined Radio

    Directory of Open Access Journals (Sweden)

    Rhiemeier Arnd-Ragnar

    2005-01-01

    Full Text Available In view of the technical and commercial boundary conditions for software-defined radio (SDR, it is suggestive to reconsider the concept anew from an unconventional point of view. The organizational principles of signal processing (rather than the signal processing algorithms themselves are the main focus of this work on modular software-defined radio. Modularity and flexibility are just two key characteristics of the SDR environment which extend smoothly into the modeling of hardware and software. In particular, the proposed model of signal processing software includes irregular, connected, directed, acyclic graphs with random node weights and random edges. Several approaches for mapping such software to a given hardware are discussed. Taking into account previous findings as well as new results from system simulations presented here, the paper finally concludes with the utility of pipelining as a general design guideline for modular software-defined radio.

  17. Renormalized Volume

    CERN Document Server

    Gover, A Rod

    2016-01-01

    For any conformally compact manifold with hypersurface boundary we define a canonical renormalized volume functional and compute an explicit, holographic formula for the corresponding anomaly. For the special case of asymptotically Einstein manifolds, our method recovers the known results. The anomaly does not depend on any particular choice of regulator, but the coefficients of divergences do. We give explicit formulae for these divergences valid for any choice of regulating hypersurface; these should be relevant to recent studies of quantum corrections to entanglement entropies. The anomaly is expressed as a conformally invariant integral of a local Q-curvature that generalizes the Branson Q-curvature by including data of the embedding. In each dimension this canonically defines a higher dimensional generalization of the Willmore energy/rigid string action. We show that the variation of these energy functionals is exactly the obstruction to solving a singular Yamabe type problem with boundary data along the...

  18. Defining Documentary Film

    DEFF Research Database (Denmark)

    Juel, Henrik

    2006-01-01

    A discussion of various attemts at defining documentary film regarding form, content, truth, stile, genre or reception - and a propoposal of a positive list of essential, but non-exclusive characteristica of documentary film......A discussion of various attemts at defining documentary film regarding form, content, truth, stile, genre or reception - and a propoposal of a positive list of essential, but non-exclusive characteristica of documentary film...

  19. Definably amenable NIP groups

    OpenAIRE

    Chernikov, Artem; Simon, Pierre

    2015-01-01

    We study definably amenable NIP groups. We develop a theory of generics, showing that various definitions considered previously coincide, and study invariant measures. Applications include: characterization of regular ergodic measures, a proof of the conjecture of Petrykowski connecting existence of bounded orbits with definable amenability in the NIP case, and the Ellis group conjecture of Newelski and Pillay connecting the model-theoretic connected component of an NIP group with the ideal s...

  20. The relative volume growth of minimal submanifolds

    DEFF Research Database (Denmark)

    Markvorsen, Steen; Palmer, V.

    2002-01-01

    The volume growth of certain well-defined subsets of minimal submanifolds in riemannian spaces are compared with the volume growth of balls and spheres ill space forms of constant curvature.......The volume growth of certain well-defined subsets of minimal submanifolds in riemannian spaces are compared with the volume growth of balls and spheres ill space forms of constant curvature....

  1. Comparison of target volume defined by CT scanning and {sup 18}F-F.D.G. PET for the radiotherapy of head and neck cancers; Comparaison des volumes cibles definis par scanographie et TEP- au [18F]-FDG pour la radiotherapie des cancers de la tete et du cou

    Energy Technology Data Exchange (ETDEWEB)

    Henriques de Figueiredo, B.; Barret, O.; Allard, M.; Fernandez, P. [Hopital Pellegrin, 33 - Bordeaux (France); Galland, S.; Demeaux, H. [Hopital Saint-Andre, 33 - Bordeaux (France); Lagarde, P.; Dejean, C.; Buj, S.; Richaud, P. [Institut Bergonie, 33 - Bordeaux (France)

    2009-10-15

    In spite of lack of correlation with anatomo-pathological pieces for these inoperable cancers, it seems that the PET allows to better adjust the anatomo-clinical target volume (C.T.V.70 Gy) by orienting, especially on the supplementary extension risks. Then, the reduction of the macroscopic tumor volume noticed in PET could be interesting in the case of a dose escalation. (N.C.)

  2. Can play be defined?

    DEFF Research Database (Denmark)

    Eichberg, Henning

    2015-01-01

    Can play be defined? There is reason to raise critical questions about the established academic demand that at phenomenon – also in humanist studies – should first of all be defined, i.e. de-lineated and by neat lines limited to a “little box” that can be handled. The following chapter develops t....... Human beings can very well understand play – or whatever phenomenon in human life – without defining it........ The academic imperative of definition seems to be linked to the positivistic attempts – and produces sometimes monstrous definitions. Have they any philosophical value for our knowledge of what play is? Definition is not a universal instrument of knowledge-building, but a culturally specific construction...

  3. Nouns to Define Homophobia

    Directory of Open Access Journals (Sweden)

    Adalberto Campo Arias

    2013-09-01

    Full Text Available Background. The term ‘homophobia’ was introduced in the academic context more than 40 years ago. However, its meaning has changed over time. Objective. To review the nouns used in the last twelve years to define homophobia. Methodology. The authors conducted a systematic search in Medline through Pubmed that included editorials, letters to editors, comments and narrative reviews, in English and Spanish. A qualitative analysis (Grounded theory was applied to analyze nouns used to define homophobia since 2001 through 2012. Results. Authors reviewed three papers including ten nouns to define homophobia, the most common noun was fear. The terms were grouped into two domains: negative attitude and discomfort with homosexuality. Conclusion. Fear is the most used word to describe homophobia. The terms were grouped into two domains: negative attitude and discomfort toward homosexuality.

  4. Defining "intermittent UVR exposure"

    DEFF Research Database (Denmark)

    Bodekær, Mette; Philipsen, Peter Alshede; Petersen, Bibi Øager;

    2016-01-01

    to define and quantify “intermittent UVR exposure” by an objective measure. Methods: A broad study population of adults and children had data collected during a summer period. Data were personal UVR dosimetry measurements, from which the number of “intermittent days” was derived, sun behaviour diaries.......001). The corresponding numbers for prediction of nevi and lentigo density by retrospective questionnaire data was lower (R2 = 0.11, R2 = 0.26, p defined objective measure of intermittent UVR exposure. This measure may provide a better prediction of solar skin damage and CMM...

  5. A prognostic model to predict survival in 867 World Health Organization-defined essential thrombocythemia at diagnosis: a study by the International Working Group on Myelofibrosis Research and Treatment.

    Science.gov (United States)

    Passamonti, Francesco; Thiele, Jürgen; Girodon, Francois; Rumi, Elisa; Carobbio, Alessandra; Gisslinger, Heinz; Kvasnicka, Hans Michael; Ruggeri, Marco; Randi, Maria Luigia; Gangat, Naseema; Vannucchi, Alessandro Maria; Gianatti, Andrea; Gisslinger, Bettina; Müllauer, Leonhard; Rodeghiero, Francesco; d'Amore, Emanuele S G; Bertozzi, Irene; Hanson, Curtis A; Boveri, Emanuela; Marino, Filippo; Maffioli, Margherita; Caramazza, Domenica; Antonioli, Elisabetta; Carrai, Valentina; Buxhofer-Ausch, Veronika; Pascutto, Cristiana; Cazzola, Mario; Barbui, Tiziano; Tefferi, Ayalew

    2012-08-01

    Diagnosis of essential thrombocythemia (ET) has been updated in the last World Health Organization (WHO) classification. We developed a prognostic model to predict survival at diagnosis, named IPSET (International Prognostic Score for ET), studying patients with WHO-defined ET. Age 60 years or older, leukocyte count ≥ 11 × 10(9)/L, and prior thrombosis significantly affected survival, by multivariable Cox regression. On the basis of the hazard ratio, we assigned 2 points to age and 1 each to leukocyte count and thrombosis. So, the IPSET model allocated 867 patients into 3 risk categories with significantly different survival: low (sum of points = 0; median survival not reached), intermediate (sum = 1-2; median survival 24.5 years), and high (sum = 3-4, median survival 13.8 years). The IPSET model was further validated in 2 independent cohorts including 132 WHO-defined ET and 234 Polycythemia Vera Study Group-defined ET patients. The IPSET model was able to predict the occurrence of thrombosis, and not to predict post-ET myelofibrosis. In conclusion, IPSET, based on age ≥ 60 years, leukocyte count ≥ 11 × 10(9)/L, and history of thrombosis allows prognostic assessment of WHO-defined ET and the validation process makes IPSET applicable in all patients phenotypically appearing as ET.

  6. On Defining Mass

    Science.gov (United States)

    Hecht, Eugene

    2011-01-01

    Though central to any pedagogical development of physics, the concept of mass is still not well understood. Properly defining mass has proven to be far more daunting than contemporary textbooks would have us believe. And yet today the origin of mass is one of the most aggressively pursued areas of research in all of physics. Much of the excitement…

  7. Defining Data Science

    OpenAIRE

    Zhu, Yangyong; Xiong, Yun

    2015-01-01

    Data science is gaining more and more and widespread attention, but no consensus viewpoint on what data science is has emerged. As a new science, its objects of study and scientific issues should not be covered by established sciences. Data in cyberspace have formed what we call datanature. In the present paper, data science is defined as the science of exploring datanature.

  8. Defining Mathematical Giftedness

    Science.gov (United States)

    Parish, Linda

    2014-01-01

    This theoretical paper outlines the process of defining "mathematical giftedness" for a present study on how primary school teaching shapes the mindsets of children who are mathematically gifted. Mathematical giftedness is not a badge of honour or some special value attributed to a child who has achieved something exceptional.…

  9. Software Defined Networking

    DEFF Research Database (Denmark)

    Caba, Cosmin Marius

    resources are limited. Hence, to counteract this trend, current QoS mechanisms must become simpler to deploy and operate, in order to motivate NSPs to employ QoS techniques instead of overprovisioning. Software Defined Networking (SDN) represents a paradigm shift in the way telecommunication and data...

  10. Defining Effective Teaching

    Science.gov (United States)

    Layne, L.

    2012-01-01

    The author looks at the meaning of specific terminology commonly used in student surveys: "effective teaching." The research seeks to determine if there is a difference in how "effective teaching" is defined by those taking student surveys and those interpreting the results. To investigate this difference, a sample group of professors and students…

  11. Defining Game Mechanics

    DEFF Research Database (Denmark)

    Sicart (Vila), Miguel Angel

    2008-01-01

    This article defins game mechanics in relation to rules and challenges. Game mechanics are methods invoked by agents for interacting with the game world. I apply this definition to a comparative analysis of the games Rez, Every Extend Extra and Shadow of the Colossus that will show the relevance...... of a formal definition of game mechanics. Udgivelsesdato: Dec 2008...

  12. Software Defined Cyberinfrastructure

    Energy Technology Data Exchange (ETDEWEB)

    Foster, Ian; Blaiszik, Ben; Chard, Kyle; Chard, Ryan

    2017-07-17

    Within and across thousands of science labs, researchers and students struggle to manage data produced in experiments, simulations, and analyses. Largely manual research data lifecycle management processes mean that much time is wasted, research results are often irreproducible, and data sharing and reuse remain rare. In response, we propose a new approach to data lifecycle management in which researchers are empowered to define the actions to be performed at individual storage systems when data are created or modified: actions such as analysis, transformation, copying, and publication. We term this approach software-defined cyberinfrastructure because users can implement powerful data management policies by deploying rules to local storage systems, much as software-defined networking allows users to configure networks by deploying rules to switches.We argue that this approach can enable a new class of responsive distributed storage infrastructure that will accelerate research innovation by allowing any researcher to associate data workflows with data sources, whether local or remote, for such purposes as data ingest, characterization, indexing, and sharing. We report on early experiments with this approach in the context of experimental science, in which a simple if-trigger-then-action (IFTA) notation is used to define rules.

  13. Defining in Classroom Activities.

    Science.gov (United States)

    Mariotti, Maria Alessandra; Fischbein, Efraim

    1997-01-01

    Discusses some aspects of the defining process in geometrical context in the reference frame of the theory of "figural concepts." Presents analysis of some examples taken from a teaching experiment at the sixth-grade level. Contains 30 references. (Author/ASK)

  14. Defining Game Mechanics

    DEFF Research Database (Denmark)

    Sicart (Vila), Miguel Angel

    2008-01-01

    This article defins game mechanics in relation to rules and challenges. Game mechanics are methods invoked by agents for interacting with the game world. I apply this definition to a comparative analysis of the games Rez, Every Extend Extra and Shadow of the Colossus that will show the relevance...... of a formal definition of game mechanics. Udgivelsesdato: Dec 2008...

  15. Review for the volume Alexei Marco. The destiny of a jeweler from Moldova, by Liliana Condraticova, work about the monographic study of the artist jeweler Alexei Marco, within Moldovan cultural space

    Directory of Open Access Journals (Sweden)

    Ana CARAS

    2012-06-01

    Full Text Available The present paper represents the review for the volume Alexei Marco. The destiny of a jeweler from Moldova, by Liliana Condraticova, published at Lumen Publishing House, a volume about the monographic study of an artist jeweler from Moldova. The work comes as a novelty element in the cultural context of Moldova. The lack of studies regarding the life and work of the masters of jewelry manufacturing, determined the author to develop a work in order to provide relevant, comprehensive information, in terms of the artistic creation of the most famous jeweler in Moldova – Alexei Marco. The study uses monographic method, a method used particularly in empirical research, which involves direct observation of territorial social unit without the use of sampling and without manipulating variables. The social reality investigated is approached in all its manifestations.

  16. Defining the fascial system.

    Science.gov (United States)

    Adstrum, Sue; Hedley, Gil; Schleip, Robert; Stecco, Carla; Yucesoy, Can A

    2017-01-01

    Fascia is a widely used yet indistinctly defined anatomical term that is concurrently applied to the description of soft collagenous connective tissue, distinct sections of membranous tissue, and a body pervading soft connective tissue system. Inconsistent use of this term is causing concern due to its potential to confuse technical communication about fascia in global, multiple discipline- and multiple profession-spanning discourse environments. The Fascia Research Society acted to address this issue by establishing a Fascia Nomenclature Committee (FNC) whose purpose was to clarify the terminology relating to fascia. This committee has since developed and defined the terms a fascia, and, more recently, the fascial system. This article reports on the FNC's proposed definition of the fascial system. Copyright © 2016 Elsevier Ltd. All rights reserved.

  17. Defining Legal Moralism

    DEFF Research Database (Denmark)

    Thaysen, Jens Damgaard

    2015-01-01

    This paper discusses how legal moralism should be defined. It is argued that legal moralism should be defined as the position that “For any X, it is always a pro tanto reason for justifiably imposing legal regulation on X that X is morally wrong (where “morally wrong” is not conceptually equivalent...... to “harmful”)”. Furthermore, a distinction between six types of legal moralism is made. The six types are grouped according to whether they are concerned with the enforcement of positive or critical morality, and whether they are concerned with criminalising, legally restricting, or refraining from legally...... protecting morally wrong behaviour. This is interesting because not all types of legal moralism are equally vulnerable to the different critiques of legal moralism that have been put forth. Indeed, I show that some interesting types of legal moralism have not been criticised at all....

  18. Define Digital Vernacular

    Institute of Scientific and Technical Information of China (English)

    刘佳; 李海英; James Stevens; Rough Nelson

    2014-01-01

    As science and technology developed, the tools of humans developed from humans’hands, to mechanical and digital technologies. The tools influ-ence almost everything in the humans’world, so does vernacular. The digital vernacular could be understood as using digital technology to vernacular; the digital means technologies. It also could be understood as doing vernacular in a digital way;the digital means data and information, in other words it can be seeking truth from facts. Define digital vernacular is not only what is digital vernacular, but also about how to do the digital vernacular and what kind of attitude we should hold to-ward the digital vernacular. Define digital vernacular as both thinking and doing.

  19. Defining local food

    DEFF Research Database (Denmark)

    Eriksen, Safania Normann

    2013-01-01

    Despite evolving local food research, there is no consistent definition of “local food.” Various understandings are utilized, which have resulted in a diverse landscape of meaning. The main purpose of this paper is to examine how researchers within the local food systems literature define local...... food, and how these definitions can be used as a starting point to identify a new taxonomy of local food based on three domains of proximity....

  20. [To define internet addiction].

    Science.gov (United States)

    Tonioni, Federico

    2013-01-01

    Internet addiction is a new behavioral disorder difficult to define, especially when referring to young teenagers who make great use of web-mediated relationships. It's necessary to separate the cases of overt dependency on those in which the abuse of internet seems to have a different value, offering the only way to achieve the possible relationship. Internet is mediating a new way of communicating and thinking, this may favor the onset of clinical phenomena intended to surprise.

  1. Decidability of definability

    CERN Document Server

    Tsankov, Manuel Bodirsky; Michael Pinsker; Todor

    2010-01-01

    For a fixed infinite structure $\\Gamma$ with finite signature $\\tau$, we study the following computational problem: Input are quantifier-free first-order $\\tau$-formulas $\\phi_0,\\phi_1,\\dots,\\phi_n$ that define relations $R_0,R_1,\\dots,R_n$ over $\\Gamma$. The question is whether the relation $R_0$ is primitive positive definable from $R_1,\\ldots,R_n$, i.e., definable by a first-order formula that uses only relation symbols for $R_1, \\dots, R_n$, equality, conjunctions, and existential quantification (disjunction, negation, and universal quantification are forbidden). We show decidability of this problem for all structures $\\Gamma$ that have a first-order definition in an ordered homogeneous structure $\\Delta$ with a finite language whose age is a Ramsey class and determined by finitely many forbidden substructures. Examples for structures $\\Gamma$ with this property are the order of the rationals, the random graph, the homogeneous universal poset, the random tournament, all homogeneous universal $C$-relations...

  2. Defining and Measuring User Experience

    DEFF Research Database (Denmark)

    Stage, Jan

    2006-01-01

    User experience is being used to denote what a user goes through while using a computerized system. The concept has gained momentum as a means to distinguish new types of applications such as games and entertainment software from more traditional work-related applications. This paper focuses...... on the intrinsic relation between definition and measurement. In the area of usability, this relation has been developed over several years. It is described how usability is defined and measured in contemporary approaches. Based on that, it is discussed to what extent we can employ experience from the conceptual...... definition of usability to develop the notion of user experience....

  3. Defining Z in Q

    CERN Document Server

    Koenigsmann, Jochen

    2010-01-01

    We show that ${\\mathbb Z}$ is definable in ${\\mathbb Q}$ by a universal first-order formula in the language of rings. We also present an $\\forall\\exists$-formula for ${\\mathbb Z}$ in ${\\mathbb Q}$ with just one universal quantifier. We exhibit new diophantine subsets of ${\\mathbb Q}$ like the set of non-squares or the complement of the image of the norm map under a quadratic extension. Finally, we show that there is no existential formula for ${\\mathbb Z}$ in ${\\mathbb Q}$, provided one assumes a strong variant of the Bombieri-Lang Conjecture for varieties over ${\\mathbb Q}$ with many ${\\mathbb Q}$-rational points.

  4. Software-Defined Cluster

    Institute of Scientific and Technical Information of China (English)

    聂华; 杨晓君; 刘淘英

    2015-01-01

    The cluster architecture has played an important role in high-end computing for the past 20 years. With the advent of Internet services, big data, and cloud computing, traditional clusters face three challenges: 1) providing flexible system balance among computing, memory, and I/O capabilities;2) reducing resource pooling overheads;and 3) addressing low performance-power efficiency. This position paper proposes a software-defined cluster (SDC) architecture to deal with these challenges. The SDC architecture inherits two features of traditional cluster: its architecture is multicomputer and it has loosely-coupled interconnect. SDC provides two new mechanisms: global I/O space (GIO) and hardware-supported native access (HNA) to remote devices. Application software can define a virtual cluster best suited to its needs from resources pools provided by a physical cluster, and traditional cluster ecosystems need no modification. We also discuss a prototype design and implementation of a 32-processor cloud server utilizing the SDC architecture.

  5. Dyscalculia Defined. NetNews. Volume 5, Number 4

    Science.gov (United States)

    LDA of Minnesota, 2005

    2005-01-01

    The focus of this issue of "NetNews" is dyscalculia, or math disability. Most of the attention over the years has been on reading and writing difficulties, thus leading to the belief that math difficulties are not very common or serious. However, it has been estimated that about 6% of school-age children experience significant math difficulties.…

  6. Asymptomatic Alzheimer disease: Defining resilience.

    Science.gov (United States)

    Hohman, Timothy J; McLaren, Donald G; Mormino, Elizabeth C; Gifford, Katherine A; Libon, David J; Jefferson, Angela L

    2016-12-06

    To define robust resilience metrics by leveraging CSF biomarkers of Alzheimer disease (AD) pathology within a latent variable framework and to demonstrate the ability of such metrics to predict slower rates of cognitive decline and protection against diagnostic conversion. Participants with normal cognition (n = 297) and mild cognitive impairment (n = 432) were drawn from the Alzheimer's Disease Neuroimaging Initiative. Resilience metrics were defined at baseline by examining the residuals when regressing brain aging outcomes (hippocampal volume and cognition) on CSF biomarkers. A positive residual reflected better outcomes than expected for a given level of pathology (high resilience). Residuals were integrated into a latent variable model of resilience and validated by testing their ability to independently predict diagnostic conversion, cognitive decline, and the rate of ventricular dilation. Latent variables of resilience predicted a decreased risk of conversion (hazard ratio 0.02, p < 0.001), and slower rates of ventricular dilation (β < -4.7, p < 2 × 10(-15)). These results were significant even when analyses were restricted to clinically normal individuals. Furthermore, resilience metrics interacted with biomarker status such that biomarker-positive individuals with low resilience showed the greatest risk of subsequent decline. Robust phenotypes of resilience calculated by leveraging AD biomarkers and baseline brain aging outcomes provide insight into which individuals are at greatest risk of short-term decline. Such comprehensive definitions of resilience are needed to further our understanding of the mechanisms that protect individuals from the clinical manifestation of AD dementia, especially among biomarker-positive individuals. © 2016 American Academy of Neurology.

  7. GEXcel Work in Progress Report Volume XII : Proceedings from GEXcel Theme 7:Getting Rid of Violence, Autumn 2010 : Getting Rid of Violence TRANSdisciplinary, TRANSnational and TRANSformative Feminist Dialogues on Embodiment, Emotions and Ethics

    OpenAIRE

    2012-01-01

    The papers of this volume represent the intense and intellectually hectic activities which took place during the seventh research theme of the GEXcel during the autumn 2010 in Linköping, Getting Rid of Violence; TRANSdisciplinary, TRANSnational and TRANSformative Feminist Dialogues on Embodiment, Emotions and Ethics. In short, the theme was called The Violence Theme 7. All the authors were GEXcel scholars for various periods of time between October and December 2010, working with their resear...

  8. Implementing Software Defined Radio

    CERN Document Server

    Grayver, Eugene

    2013-01-01

    Software Defined Radio makes wireless communications easier, more efficient, and more reliable. This book bridges the gap between academic research and practical implementation. When beginning a project, practicing engineers, technical managers, and graduate students can save countless hours by considering the concepts presented in these pages. The author covers the myriad options and trade-offs available when selecting an appropriate hardware architecture. As demonstrated here, the choice between hardware- and software-centric architecture can mean the difference between meeting an aggressive schedule and bogging down in endless design iterations. Because of the author’s experience overseeing dozens of failed and successful developments, he is able to present many real-life examples. Some of the key concepts covered are: Choosing the right architecture for the market – laboratory, military, or commercial Hardware platforms – FPGAs, GPPs, specialized and hybrid devices Standardization efforts to ens...

  9. Defining cyber warfare

    Directory of Open Access Journals (Sweden)

    Dragan D. Mladenović

    2012-04-01

    Full Text Available Cyber conflicts represent a new kind of warfare that is technologically developing very rapidly. Such development results in more frequent and more intensive cyber attacks undertaken by states against adversary targets, with a wide range of diverse operations, from information operations to physical destruction of targets. Nevertheless, cyber warfare is waged through the application of the same means, techniques and methods as those used in cyber criminal, terrorism and intelligence activities. Moreover, it has a very specific nature that enables states to covertly initiate attacks against their adversaries. The starting point in defining doctrines, procedures and standards in the area of cyber warfare is determining its true nature. In this paper, a contribution to this effort was made through the analysis of the existing state doctrines and international practice in the area of cyber warfare towards the determination of its nationally acceptable definition.

  10. Acquisition Cycle Time: Defining the Problem

    Science.gov (United States)

    2016-04-01

    prescribe appetite suppression and fiscal discipline . Still others diagnose inept management and excessive bureaucracy, and prescribe streamlined...complex the system, the higher this bound. • Software development consists of completing known work and discovering new work. There are fundamental ... taxonomy of acquisition risk categories, with corresponding development timelines. In that report, a low-risk acquisition is defined to be one that

  11. Staff Working Papers of the Drug Law Evaluation Project. A Companion Volume to the Final Report of the Joint Committee of New York Drug Law Evaluation.

    Science.gov (United States)

    1978

    The papers in this volume were prepared as part of an evaluation of the effects of the strict 1973 New York State drug laws. The first paper explores the effects of the laws on heroin use. It analyzes the trends of various indicators of heroin use in New York State over a period of several years. In order to isolate movements unique to New York,…

  12. Spacecraft Habitable Volume: Results of an Interdisciplinary Workshop

    Science.gov (United States)

    Fitts, David J.; Connolly, Janis; Howard, Robert

    2011-01-01

    NASA's Human Exploration Framework Team posed the question: "Is 80 cubic meters per person of habitable volume acceptable for a proposed Deep Space Habitat?" The goal of the workshop was to address the "net habitable volume" necessary for long-duration human spaceflight missions and identify design and psychological issues and mitigations. The objectives were: (1) Identify psychological factors -- i.e., "stressors" -- that impact volume and layout specifications for long duration missions (2) Identify mitigation strategies for stressors, especially those that can be written as volume design specifications (3) Identify a forward research roadmap -- i.e., what future work is needed to define and validate objective design metrics? (4) Provide advisories on the human factors consequences of poor net habitable volume allocation and layout design.

  13. Defining the Anthropocene

    Science.gov (United States)

    Lewis, Simon; Maslin, Mark

    2016-04-01

    Time is divided by geologists according to marked shifts in Earth's state. Recent global environmental changes suggest that Earth may have entered a new human-dominated geological epoch, the Anthropocene. Should the Anthropocene - the idea that human activity is a force acting upon the Earth system in ways that mean that Earth will be altered for millions of years - be defined as a geological time-unit at the level of an Epoch? Here we appraise the data to assess such claims, first in terms of changes to the Earth system, with particular focus on very long-lived impacts, as Epochs typically last millions of years. Can Earth really be said to be in transition from one state to another? Secondly, we then consider the formal criteria used to define geological time-units and move forward through time examining whether currently available evidence passes typical geological time-unit evidence thresholds. We suggest two time periods likely fit the criteria (1) the aftermath of the interlinking of the Old and New Worlds, which moved species across continents and ocean basins worldwide, a geologically unprecedented and permanent change, which is also the globally synchronous coolest part of the Little Ice Age (in Earth system terms), and the beginning of global trade and a new socio-economic "world system" (in historical terms), marked as a golden spike by a temporary drop in atmospheric CO2, centred on 1610 CE; and (2) the aftermath of the Second World War, when many global environmental changes accelerated and novel long-lived materials were increasingly manufactured, known as the Great Acceleration (in Earth system terms) and the beginning of the Cold War (in historical terms), marked as a golden spike by the peak in radionuclide fallout in 1964. We finish by noting that the Anthropocene debate is politically loaded, thus transparency in the presentation of evidence is essential if a formal definition of the Anthropocene is to avoid becoming a debate about bias. The

  14. OAST Theme Workshop. Volume 3: Working group summary. 8: Structures, dynamics (M-2). A. Statement. B. Technology needs (form 1). C. Priority assessments (form 2)

    Science.gov (United States)

    1976-01-01

    A technology program on large space structures was defined to respond to common need perceived for five of the six themes. Greatly expanded power, facilities, and communications/sensing requirements appear to demand a new structures technology for construction in space. Requirements to construct huge structural arrays with precision surfaces in space will need creative research efforts to identify practical structural elements and construction techniques. Requirements for advanced transportation structures were defined to respond to the space transportation theme. Because of the criticality of thermal structures to achieve lower cost transportation systems, renewed emphasis on technology in this area is recommended. A second technology needing renewed emphasis is the area of recovery and landing technology structures to permit full reuse of launch vehicle propulsion elements.

  15. Defining biocultural approaches to conservation.

    Science.gov (United States)

    Gavin, Michael C; McCarter, Joe; Mead, Aroha; Berkes, Fikret; Stepp, John Richard; Peterson, Debora; Tang, Ruifei

    2015-03-01

    We contend that biocultural approaches to conservation can achieve effective and just conservation outcomes while addressing erosion of both cultural and biological diversity. Here, we propose a set of guidelines for the adoption of biocultural approaches to conservation. First, we draw lessons from work on biocultural diversity and heritage, social-ecological systems theory, integrated conservation and development, co-management, and community-based conservation to define biocultural approaches to conservation. Second, we describe eight principles that characterize such approaches. Third, we discuss reasons for adopting biocultural approaches and challenges. If used well, biocultural approaches to conservation can be a powerful tool for reducing the global loss of both biological and cultural diversity.

  16. Integers annual volume 2013

    CERN Document Server

    Landman, Bruce

    2014-01-01

    ""Integers"" is a refereed online journal devoted to research in the area of combinatorial number theory. It publishes original research articles in combinatorics and number theory. This work presents all papers of the 2013 volume in book form.

  17. Defining Political Marketing

    DEFF Research Database (Denmark)

    Ormrod, Robert P.

    ’ and ‘narrow’ interpretations of political marketing, the nature of the political marketing exchange, political relationship marketing and how one can integrate the stakeholder concept into an understanding of political marketing. Finally, we propose a definition of political marketing that differs from......The aim of this working paper is to develop a definition of political marketing that builds on the political rather than commercial marketing literature. This aim is motivated by the need to make explicit our understanding of what political marketing is, a necessary exercise when discussing theory......, concepts and empirical methods in political marketing. We first present five existing definitions of political marketing that have been selected to represent advances in research from the origins of academic research into political marketing in the mid-1970’s to the present day. After this we discuss ‘wide...

  18. Volume Entropy

    CERN Document Server

    Astuti, Valerio; Rovelli, Carlo

    2016-01-01

    Building on a technical result by Brunnemann and Rideout on the spectrum of the Volume operator in Loop Quantum Gravity, we show that the dimension of the space of the quadrivalent states --with finite-volume individual nodes-- describing a region with total volume smaller than $V$, has \\emph{finite} dimension, bounded by $V \\log V$. This allows us to introduce the notion of "volume entropy": the von Neumann entropy associated to the measurement of volume.

  19. Social Work Research

    DEFF Research Database (Denmark)

    Social work research has gathered a greater transparency and clarity of identity in North American and parts of Europe. Furthermore, the rapid emergence of social work research in other European countries, China, India, Japan and elsewhere in Asia and Pacific Rim countries, and gradually in South...... understanding of the different aspects involved in the research. Volume One: Historical Trajectories, Purposes and Key Concepts Volume Two: Key Decisions about Research Strategy Volume Three: The Practice of Social Work Research Volume Four: The Contexts of Social Work Research...

  20. Case work

    DEFF Research Database (Denmark)

    Shaw, Ian Frank

    2016-01-01

    Answers to the question just what is the ?case? partly defined the fields of sociology and social work in early 20th century Chicago. Drawing on the archives of the University of Chicago, I describe and appraise the way the ?case? figured in social work at Chicago and elsewhere. I ask...... the corresponding question of sociology. Finally, I briefly consider why not much came of social work and sociology ploughing similar territory in ways that served for a time to hallmark their identities. This analysis opens up ways of rethinking how social work and sociological research are distinctive...

  1. Volume Regulated Channels

    DEFF Research Database (Denmark)

    Klausen, Thomas Kjær

    - serves a multitude of functions in the mammalian cell, regulating the membrane potential (Em), cell volume, protein activity and the driving force for facilitated transporters giving Cl- and Cl- channels a major potential of regulating cellular function. These functions include control of the cell cycle...... of volume perturbations evolution have developed system of channels and transporters to tightly control volume homeostasis. In the past decades evidence has been mounting, that the importance of these volume regulated channels and transporters are not restricted to the defense of cellular volume......, controlled cell death and cellular migration. Volume regulatory mechanisms has long been in focus for regulating cellular proliferation and my thesis work have been focusing on the role of Cl- channels in proliferation with specific emphasis on ICl, swell. Pharmacological blockage of the ubiquitously...

  2. Armored Family of Vehicles (AFV) Concept Exploration Definition Phase Automation and Communication Work Plan for Command, Control, Communications, Computer Development (C4). Volume 15

    Science.gov (United States)

    1988-08-30

    Architecture for MS I. VCOS must support B2C2. ASSUMPTION: AFVTF will provide coordinated first cut. PRODUCT: Functional Description (FD). ACTION: CACCA ...C41 Lead for Action: CACA C41 Lead Support: CAC(CATA), CACCA (MID, 31), LOGCEN(C31, AFVTF(CD), CECCM, TACOM. Work Group Support: ACRWG, Requirements

  3. Definições operacionais das características definidoras do diagnóstico de enfermagem Volume de Líquidos Excessivo Definiciones operacionales de las características definidoras del diagnóstico de enfermería Volumen de Líquídos Excesivo Operational definitions of the defining characterístics of the nursing diagnosis Fluid Volume Excess

    Directory of Open Access Journals (Sweden)

    Rita Narriman Silva de Oliveira Boery

    2005-06-01

    Full Text Available As definições operacionais são requisitos importantes no ensino da Semiologia e Semiotécnica nos Cursos de Graduação e Pós-Graduação em Enfermagem. Este estudo descritivo, acerca das definições operacionais elaboradas para as características definidoras do diagnóstico de enfermagem Volume de Líquidos Excessivo em portadores de cardiopatias foi realizado a partir de revisão da literatura, no período de 1985 a 2001. As definições operacionais foram analisadas criticamente por quatro enfermeiros especialistas em diferentes campos clínicos de atuação. Após os ajustes sugeridos por esses especialistas, os dados foram enviados a uma consultora técnica, para avaliação conclusiva.Las definiciones operacionales son subsidios importantes para la ensveñanza de Semiologia y Semiotécnica en los cursos de pre y pós grado. Este estudio descriptivo, aurea de las caracteristicas definidoras del diagnóstico de enfermaria Volumen de Liquidos Excesivo en pacientes cardíacos, que realizado a partir de revision de literatura, del período de 1985 a 2001. las definiciones operacionales elaboradas fueron analizadas por cuatro enfermeros especialistas que actuavan en diferentes campos clínicos. Despues de realizar las correcciones sugeridas por esas especialistas, los dados fueron enviados a uma consultora técnica para evoluación final.Operational definitions are important tools for teaching Semiology and Semiotechuiques both for undergraduate and graduate nursing students. This descriptive study on the operational definitions of the defining characteristics of nursing diagnosis Fluid Volume Excess in cardiac patients was based on literature review regarding the period from 1985 to 2001. The operational definitions were analyzed by four expert nurses from different clinical areas. After the suggested corrections were made, the data was submitted to a technical consultant for final evaluation.

  4. Paid work and unpaid work

    DEFF Research Database (Denmark)

    Bonke, Jens

    Time-use information is preferably obtained from diaries, as this method is considered more reliable than information from questionnaires. The diary-technique seems to be unique in catching the rhythm of every day life and thereby the structuring of work and leisure during a well-defined and memo...

  5. Chemically defined medium and Caenorhabditis elegans

    Science.gov (United States)

    Szewczyk, Nathaniel J.; Kozak, Elena; Conley, Catharine A.

    2003-01-01

    BACKGROUND: C. elegans has been established as a powerful genetic system. Use of a chemically defined medium (C. elegans Maintenance Medium (CeMM)) now allows standardization and systematic manipulation of the nutrients that animals receive. Liquid cultivation allows automated culturing and experimentation and should be of use in large-scale growth and screening of animals. RESULTS: We find that CeMM is versatile and culturing is simple. CeMM can be used in a solid or liquid state, it can be stored unused for at least a year, unattended actively growing cultures may be maintained longer than with standard techniques, and standard C. elegans protocols work well with animals grown in defined medium. We also find that there are caveats to using defined medium. Animals in defined medium grow more slowly than on standard medium, appear to display adaptation to the defined medium, and display altered growth rates as they change the composition of the defined medium. CONCLUSIONS: As was suggested with the introduction of C. elegans as a potential genetic system, use of defined medium with C. elegans should prove a powerful tool.

  6. Software-defined anything challenges status quo

    Energy Technology Data Exchange (ETDEWEB)

    Simpson, Wayne; Borders, Tammie

    2015-01-01

    INL successfully developed a proof of concept for "Software Defined Anything" by emulating the laboratory's business applications that run on Virtual Machines. The work INL conducted demonstrates to industry on how this methodology can be used to improve security, automate and repeat processes, and improve consistency.

  7. Defining Incident Management Processes for CSIRTs: A Work in Progress

    Science.gov (United States)

    2004-10-01

    Institute 7799 Part 2 • Control Objectives for Information and related Technology ( COBIT ) • Federal Financial Institutions Examination Council...British Standards Institute 7799 Part 2 • Control Objectives for Information and related Technology ( COBIT ) • Information Technology Infrastructure...Operations COBIT Control Objectives for Information and related Technology (http://www.isaca.org/ cobit ) CSF critical success factor CSIRT computer

  8. Defining Neighborhood Boundaries for Social Measurement: Advancing Social Work Research

    Science.gov (United States)

    Foster, Kirk A.; Hipp, J. Aaron

    2011-01-01

    Much of the current neighborhood-based research uses variables aggregated on administrative boundaries such as zip codes, census tracts, and block groups. However, other methods using current technological advances in geographic sciences may broaden our ability to explore the spatial concentration of neighborhood factors affecting individuals and…

  9. Sperry low-temperature geothermal conversion system. Volume I. Organic-working-fluid properties. Final report. [R-114, 1,2-dichlorotetrafluorethane

    Energy Technology Data Exchange (ETDEWEB)

    Carroll, C.; Hules, K.R.; Langley, R.; Toekes, B.; Wilson, D.P.

    1981-01-01

    Measurements of the physical properties of R-114 in the compressed liquid and dense gas regions are reported. Included are: experimental studies of the thermodynamic properties of R-114, enthalpy measurement by throttling experiment, engineering model of the thermodynamic properties of R-114, feasibility study to dissociate R-114 with a four-cycle gasoline engine, transport properties of R-114, analytical procedure to determine impurities in R-114, toxicological information on Freons, and a literature search of published properties of R-114, other refrigerants, and other potential working fluids. (LEW)

  10. Reduced volume and increased training intensity elevate muscle Na+/K+ pump {alpha}2-subunit expression as well as short- and long-term work capacity in humans

    DEFF Research Database (Denmark)

    Bangsbo, Jens; Gunnarsson, Thomas Petursson; Wendell, Jesper;

    2009-01-01

    The present study examined muscle adaptations and alterations in work capacity in endurance-trained runners as a result of a reduced amount of training combined with speed endurance training. Seventeen runners were for a 6- to 9-wk period assigned to either a speed endurance group with a 25......% reduction in the amount of training but including speed endurance training consisting of 6-12 30-s sprint runs 3-4 times a week (SET, n=12) or a control group (CON, n=5), which continued the endurance training (about 55 km(.)wk(-1)). For SET the expression of the muscle Na(+)/K(+) pump alpha2-subunit was 68......% higher (Ptraining period. In SET, VO2-max...

  11. A proposed application programming interface for a physical volume repository

    Science.gov (United States)

    Jones, Merritt; Williams, Joel; Wrenn, Richard

    1996-01-01

    The IEEE Storage System Standards Working Group (SSSWG) has developed the Reference Model for Open Storage Systems Interconnection, Mass Storage System Reference Model Version 5. This document, provides the framework for a series of standards for application and user interfaces to open storage systems. More recently, the SSSWG has been developing Application Programming Interfaces (APIs) for the individual components defined by the model. The API for the Physical Volume Repository is the most fully developed, but work is being done on APIs for the Physical Volume Library and for the Mover also. The SSSWG meets every other month, and meetings are open to all interested parties. The Physical Volume Repository (PVR) is responsible for managing the storage of removable media cartridges and for mounting and dismounting these cartridges onto drives. This document describes a model which defines a Physical Volume Repository, and gives a brief summary of the Application Programming Interface (API) which the IEEE Storage Systems Standards Working Group (SSSWG) is proposing as the standard interface for the PVR.

  12. Defining Tobacco Regulatory Science Competencies.

    Science.gov (United States)

    Wipfli, Heather L; Berman, Micah; Hanson, Kacey; Kelder, Steven; Solis, Amy; Villanti, Andrea C; Ribeiro, Carla M P; Meissner, Helen I; Anderson, Roger

    2017-02-01

    In 2013, the National Institutes of Health and the Food and Drug Administration funded a network of 14 Tobacco Centers of Regulatory Science (TCORS) with a mission that included research and training. A cross-TCORS Panel was established to define tobacco regulatory science (TRS) competencies to help harmonize and guide their emerging educational programs. The purpose of this paper is to describe the Panel's work to develop core TRS domains and competencies. The Panel developed the list of domains and competencies using a semistructured Delphi method divided into four phases occurring between November 2013 and August 2015. The final proposed list included a total of 51 competencies across six core domains and 28 competencies across five specialized domains. There is a need for continued discussion to establish the utility of the proposed set of competencies for emerging TRS curricula and to identify the best strategies for incorporating these competencies into TRS training programs. Given the field's broad multidisciplinary nature, further experience is needed to refine the core domains that should be covered in TRS training programs versus knowledge obtained in more specialized programs. Regulatory science to inform the regulation of tobacco products is an emerging field. The paper provides an initial list of core and specialized domains and competencies to be used in developing curricula for new and emerging training programs aimed at preparing a new cohort of scientists to conduct critical TRS research. © The Author 2016. Published by Oxford University Press on behalf of the Society for Research on Nicotine and Tobacco. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  13. Defining asthma in genetic studies

    NARCIS (Netherlands)

    Koppelman, GH; Postma, DS; Meijer, G.

    1999-01-01

    Genetic studies have been hampered by the lack of a gold standard to diagnose asthma. The complex nature of asthma makes it more difficult to identify asthma genes. Therefore, approaches to define phenotypes, which have been successful in other genetically complex diseases, may be applied to define

  14. Defining asthma in genetic studies

    NARCIS (Netherlands)

    Koppelman, GH; Postma, DS; Meijer, G.

    1999-01-01

    Genetic studies have been hampered by the lack of a gold standard to diagnose asthma. The complex nature of asthma makes it more difficult to identify asthma genes. Therefore, approaches to define phenotypes, which have been successful in other genetically complex diseases, may be applied to define

  15. Defining and Classifying Interest Groups

    DEFF Research Database (Denmark)

    Baroni, Laura; Carroll, Brendan; Chalmers, Adam;

    2014-01-01

    The interest group concept is defined in many different ways in the existing literature and a range of different classification schemes are employed. This complicates comparisons between different studies and their findings. One of the important tasks faced by interest group scholars engaged...... in large-N studies is therefore to define the concept of an interest group and to determine which classification scheme to use for different group types. After reviewing the existing literature, this article sets out to compare different approaches to defining and classifying interest groups with a sample...

  16. Theoretical approaches to elections defining

    Directory of Open Access Journals (Sweden)

    Natalya V. Lebedeva

    2011-01-01

    Full Text Available Theoretical approaches to elections defining develop the nature, essence and content of elections, help to determine their place and a role as one of the major national law institutions in democratic system.

  17. Defining Modules, Modularity and Modularization

    DEFF Research Database (Denmark)

    Miller, Thomas Dedenroth; Pedersen, Per Erik Elgård

    The paper describes the evolution of the concept of modularity in a historical perspective. The main reasons for modularity are: create variety, utilize similarities, and reduce complexity. The paper defines the terms: Module, modularity, and modularization.......The paper describes the evolution of the concept of modularity in a historical perspective. The main reasons for modularity are: create variety, utilize similarities, and reduce complexity. The paper defines the terms: Module, modularity, and modularization....

  18. 基于3D-CT、4D-CT和锥形束CT定义的非小细胞肺癌内靶区比较%Comparison of internal target volumes defined on three-dimensional CT, four-dimensional CT and cone-beam CT images of non-small-cell lung cancer

    Institute of Scientific and Technical Information of China (English)

    李奉祥; 李建彬; 马志芳; 张英杰; 邢军; 戚焕鹏; 尚东平; 余宁莎

    2014-01-01

    Objective To compare positional and volumetric differences between internal target volumes defined on three-dimensional CT (3D-CT),four-dimensional CT (4D-CT) and cone-beam CT (CBCT) images of non-small-cell lung cancer.Methods Thirty-one patients with NSCLC sequentially underwent 3D-CT and 4D-CT simulation scans of the thorax during free breathing.A 3D conformal treatment plan was created based on 3D-CT.The CBCT images were obtained in the first fraction and registered to the planning CT using the bony anatomy registration.All target volumes were contoured with the same protocol by a radiation oncologist.GTVs were contoured based on 3D-CT,maximum intensity projection (MIP) of 4D-CT and CBCT.CTV3D,ITVMIPand ITVCBCTWere defined with a margin of 7 mm accounting for microscopic disease.ITV10mm and ITV5 mm were defined based on CTV3D.ITV10 mm with a margin of 5 mm in LR,AP directions and 10 mm in CC direction,while ITV5 mm with an isotropic internal margin (IM) of 5 mm.The differences in the position,size,Dice's similarity coefficient (DSC) and inclusion relation of different volumes were compared.Results The median size ratio of ITV10 mm,ITV5mm,ITVMIPto ITVCBCTwere 2.33,1.88,1.03 respectively for tumors in the upper lobe and 2.13,1.76,1.10 respectively for tumors in the middle-lower lobe.The median DSC of ITVMIP and ITVCBCT(0.83) was greater than that of ITV10 mm and ITVcBcT (0.6) and ITV5 mm and ITVCBCT (0.66) for all patients (Z =-4.86,-4.86,P < 0.05).The median percentages of ITVCBCT not included in ITV10 mm,ITV5 mm,ITVMIPwere 0.10%,1.63% and 15.21% respectively,while the median percentage of ITV10mm,ITV5mm,ITVMIP,not included in ITVCBCT were 57.08%,48.89% and 20.04%,respectively.The median percentage of ITVCBCT not included in ITV5 mm was 1.24% for tumors in the upper lobe and 5.8% for tumors in the middle-lower lobe.Conclusions The individual ITV based on 4D-CT can't encompass the ITV based on CBCT effectively.The use of the ITV derived from 4

  19. Working Papers in Dialogue Modeling. Volume 1

    Science.gov (United States)

    1977-01-01

    because (1, There are no "it"s in previous clauses, (2) The subject of the previous clause "I" isn’t neuter and (3) The object "Runoff" is neuter ...are thus "the same" above a certain level, but different below that level. This difference is the reason why statements like "La Jolla is The Jewel...ignore the distinction was to run the risk of creating such nonsense a’-.! s; or My dog contains three letters. My " dog " is a hearty eater

  20. MITA Working Papers in Psycholinguistics, Volume 2.

    Science.gov (United States)

    Otsu, Yukio, Ed.

    Seven original research papers are presented. The titles and authors are as follows: "Acquisition of the Argument-Structure of Verbs" (Mika Endo); "A Note on Semantic Selection" (Yoshio Endo); "The Governing Category Parameter in Second Language" (Makiko Hirakawa); "The Use of Connectives in English Academic Papers Written by Japanese Students"…

  1. Case Studies Working Group Report Volume 2

    Science.gov (United States)

    2012-03-01

    that running the Domestic Policy Council was “an alba - tross, absorbing vast quantities of administrative en- ergy, creating conflicts within the White...ecutor of the International Criminal Court Luis Moreno -Ocampo is available from www.aegistrust.org/index.php?option=com_content &task=view&id=746...gained tremendous ground in its fight against the FARC. A high-ranking FARC leader, Nelly Avila Moreno (also known as Karina) surrendered on May 18

  2. Working Papers in Dialogue Modeling. Volume 2

    Science.gov (United States)

    1977-01-01

    atheletes have low blood pressure. Schwarzenegger is an athlete. (Therefore) Schwarzenegger has low blood pressure. The formal structure of these...AFB Denver, CO 80230 Dr. Arnold F. »Canarlck Honeyol I, Inc. 2600 Ridgoway Pkuy. Minneapolis, MN 55413 Or. MiIton S. Kalz, Chief Individual

  3. Defining the states of consciousness.

    Science.gov (United States)

    Tassi, P; Muzet, A

    2001-03-01

    Consciousness remains an elusive concept due to the difficulty to define what has been regarded for many years as a subjective experience, therefore irrelevant for scientific study. Recent development in this field of research has allowed to provide some new insight to a possible way to define consciousness. Going through the extensive literature in this domain, several perspectives are proposed to define this concept. (1) Consciousness and Attention may not reflect the same process. (2) Consciousness during wake and sleep may not involve the same mechanisms. (3) Besides physiological states of consciousness, human beings can experience modified states of consciousness either by self-training (transcendental meditation, hypnosis, etc.) or by drug intake (hallucinogens, anaesthetics, etc.). Altogether, we address the question of a more precise terminology, given the theoretical weight words can convey. To this respect, we propose different definitions for concepts like consciousness, vigilance, arousal and alertness as candidates to separate functional entities.

  4. Direct Multifield Volume Ray Casting of Fiber Surfaces.

    Science.gov (United States)

    Wu, Kui; Knoll, Aaron; Isaac, Benjamin J; Carr, Hamish; Pascucci, Valerio

    2017-01-01

    Multifield data are common in visualization. However, reducing these data to comprehensible geometry is a challenging problem. Fiber surfaces, an analogy of isosurfaces to bivariate volume data, are a promising new mechanism for understanding multifield volumes. In this work, we explore direct ray casting of fiber surfaces from volume data without any explicit geometry extraction. We sample directly along rays in domain space, and perform geometric tests in range space where fibers are defined, using a signed distance field derived from the control polygons. Our method requires little preprocess, and enables real-time exploration of data, dynamic modification and pixel-exact rendering of fiber surfaces, and support for higher-order interpolation in domain space. We demonstrate this approach on several bivariate datasets, including analysis of multi-field combustion data.

  5. The Cultural History of Work

    DEFF Research Database (Denmark)

    A Cultural History of Work is a multi-volume project on the history of work in the western world from Antiquity to the 21st century. The series will consist of six illustrated volumes, each devoted to an examination of work in one of six historical periods (Antiquity, The Medieval Age, The Early ...

  6. Defining the Internet of Things

    OpenAIRE

    Benghozi, Pierre-Jean; Bureau, Sylvain; Massit-Folléa, Françoise

    2012-01-01

    How can a definition be given to what does not yet exist ? The Internet of Things, as it is conceptualized by researchers or imagined by science-fiction writers such as Bruce Sterling, is not yet reality and if we try to define it accurately we risk rash predictions. In order to better comprehend this notion, let us first define the main principles of the IoT as given in research papers and reports on the subject. Definitions gradually established Almost all agree that the Internet of Things...

  7. Defining the Internet of Things

    OpenAIRE

    Benghozi, Pierre-Jean; Bureau, Sylvain; Massit-Folléa, Françoise

    2012-01-01

    How can a definition be given to what does not yet exist ? The Internet of Things, as it is conceptualized by researchers or imagined by science-fiction writers such as Bruce Sterling, is not yet reality and if we try to define it accurately we risk rash predictions. In order to better comprehend this notion, let us first define the main principles of the IoT as given in research papers and reports on the subject. Definitions gradually established Almost all agree that the Internet of Things...

  8. Volumes of Polytopes Without Triangulations

    CERN Document Server

    Enciso, Michael

    2014-01-01

    We introduce a new formalism for defining and computing the volumes of completely general polytopes in any dimension. The expressions that we obtain for these volumes are independent of any triangulation, and manifestly depend only on the vertices of the underlying polytope. As one application of this formalism, we obtain new expressions for tree-level, n-point NMHV amplitudes in N=4 Super Yang-Mills (SYM) theory.

  9. Defined medium for Moraxella bovis.

    OpenAIRE

    Juni, E; Heym, G A

    1986-01-01

    A defined medium (medium MB) for Moraxella bovis was formulated. Nineteen strains grew well on medium MB. One strain was auxotrophic for asparagine, and another was auxotrophic for methionine. Strains of M. equi and M. lacunata also grew on medium MB. All strains had an absolute requirement for thiamine and were stimulated by or actually required the other growth factors in the medium.

  10. Indico CONFERENCE: Define the Programme

    CERN Document Server

    CERN. Geneva; Ferreira, Pedro

    2017-01-01

    In this tutorial you are going to learn how to define the programme of a conference in Indico. The program of your conference is divided in different “tracks”. Tracks represent the subject matter of the conference, such as “Online Computing”, “Offline Computing”, and so on.

  11. Defining and Measuring User Experience

    DEFF Research Database (Denmark)

    Stage, Jan

    2006-01-01

    on the intrinsic relation between definition and measurement. In the area of usability, this relation has been developed over several years. It is described how usability is defined and measured in contemporary approaches. Based on that, it is discussed to what extent we can employ experience from the conceptual...

  12. Defining sphincter of oddi dysfunction

    DEFF Research Database (Denmark)

    Funch-Jensen, P

    1996-01-01

    Sphincter of Oddi (SO) dysmotility may give rise to pain. The golden standard for the demonstration of SO dysfunction is endoscopic manometry. A number of abnormalities are observed in patients with postcholecystectomy pain and in patients with idiopathic recurrent pancreatitis. Criteria for defi...... for defining SO dysfunction and the possible mechanisms for the precipitation of pain are discussed....

  13. Defined medium for Moraxella bovis.

    Science.gov (United States)

    Juni, E; Heym, G A

    1986-10-01

    A defined medium (medium MB) for Moraxella bovis was formulated. Nineteen strains grew well on medium MB. One strain was auxotrophic for asparagine, and another was auxotrophic for methionine. Strains of M. equi and M. lacunata also grew on medium MB. All strains had an absolute requirement for thiamine and were stimulated by or actually required the other growth factors in the medium.

  14. Defined medium for Moraxella bovis.

    OpenAIRE

    1986-01-01

    A defined medium (medium MB) for Moraxella bovis was formulated. Nineteen strains grew well on medium MB. One strain was auxotrophic for asparagine, and another was auxotrophic for methionine. Strains of M. equi and M. lacunata also grew on medium MB. All strains had an absolute requirement for thiamine and were stimulated by or actually required the other growth factors in the medium.

  15. Network Coded Software Defined Networking

    DEFF Research Database (Denmark)

    Krigslund, Jeppe; Hansen, Jonas; Roetter, Daniel Enrique Lucani

    2015-01-01

    Software Defined Networking (SDN) and Network Coding (NC) are two key concepts in networking that have garnered a large attention in recent years. On the one hand, SDN's potential to virtualize services in the Internet allows a large flexibility not only for routing data, but also to manage buffe...

  16. Defining and Differentiating the Makerspace

    Science.gov (United States)

    Dousay, Tonia A.

    2017-01-01

    Many resources now punctuate the maker movement landscape. However, some schools and communities still struggle to understand this burgeoning movement. How do we define these spaces and differentiate them from previous labs and shops? Through a multidimensional framework, stakeholders should consider how the structure, access, staffing, and tools…

  17. Control of System with Defined Risk Level

    Directory of Open Access Journals (Sweden)

    Pavol Tomasov

    2002-01-01

    Full Text Available In the following paper the basic requirements for system control with defined risk level is presented. The paper should be an introduction to describe of theoretical apparatus, which was created during some years of research work in the Department of information and safety systems in this area. It a modification or creation of new parts of Information theory, System theory, and Control theory means. This parts are necessary for the analysis and synthesis tasks in the systems where dominant attribute of control is defined risk level. The basic problem is the creation of protect mechanism again the threats from inside and from controlled system environs. For each risk reduction mechanism is needed some redundancy which should be into control algorithm to put by exactly determined way.

  18. Utilities and offsites design baseline. Outside Battery Limits Facility 6000 tpd SRC-I Demonstration Plant. Volume 1

    Energy Technology Data Exchange (ETDEWEB)

    None

    1984-05-25

    As part of the overall Solvent Refined Coal (SRC-1) project baseline being prepared by International Coal Refining Company (ICRC), the RUST Engineering Company is providing necessary input for the Outside Battery Limits (OSBL) Facilities. The project baseline is comprised of: design baseline - technical definition of work; schedule baseline - detailed and management level 1 schedules; and cost baseline - estimates and cost/manpower plan. The design baseline (technical definition) for the OSBL Facilities has been completed and is presented in Volumes I, II, III, IV, V and VI. The OSBL technical definition is based on, and compatible with, the ICRC defined statement of work, design basis memorandum, master project procedures, process and mechanical design criteria, and baseline guidance documents. The design basis memorandum is included in Paragraph 1.3 of Volume I. The baseline design data is presented in 6 volumes. Volume I contains the introduction section and utility systems data through steam and feedwater. Volume II continues with utility systems data through fuel system, and contains the interconnecting systems and utility system integration information. Volume III contains the offsites data through water and waste treatment. Volume IV continues with offsites data, including site development and buildings, and contains raw materials and product handling and storage information. Volume V contains wastewater treatment and solid wastes landfill systems developed by Catalytic, Inc. to supplement the information contained in Volume III. Volume VI contains proprietary information of Resources Conservation Company related to the evaporator/crystallizer system of the wastewater treatment area.

  19. 33 CFR 211.1 - Real estate defined.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 3 2010-07-01 2010-07-01 false Real estate defined. 211.1... DEFENSE REAL ESTATE ACTIVITIES OF THE CORPS OF ENGINEERS IN CONNECTION WITH CIVIL WORKS PROJECTS Real Estate; General § 211.1 Real estate defined. The term real estate as used in this part includes land...

  20. Defining and Assessing Team Skills of Business and Accountancy Students

    Science.gov (United States)

    Alghalith, Nabil; Blum, Michael; Medlock, Amanda; Weber, Sandy

    2004-01-01

    The objectives of the project are (1) to define the skills necessary for students to work effectively with others to achieve common goals, and (2) to develop an assessment instrument to measure student progress toward achieving these skills. The defined skill set will form a basis for common expectations related to team skills that will be shared…

  1. Software defined radio architectures evaluation

    OpenAIRE

    Palomo, Alvaro; Villing, Rudi; Farrell, Ronan

    2008-01-01

    This paper presents an performance evaluation of GNU Radio and OSSIE, two open source Software Defined Radio (SDR) architectures. The two architectures were compared by running implementations of a BPSK waveform utilising a software loopback channel on each. The upper bound full duplex throughput was found to be around 700kbps in both cases, though OSSIE was slightly faster than GNU Radio. CPU and memory loads did not differ significantly.

  2. AIDS defining disease: Disseminated cryptococcosis

    Directory of Open Access Journals (Sweden)

    Roshan Anupama

    2006-01-01

    Full Text Available Disseminated cryptococcosis is one of the acquired immune deficiency syndrome defining criteria and the most common cause of life threatening meningitis. Disseminated lesions in the skin manifest as papules or nodules that mimic molluscum contagiosum (MC. We report here a human immunodeficiency virus positive patient who presented with MC like lesions. Disseminated cryptococcosis was confirmed by India ink preparation and histopathology. The condition of the patient improved with amphotercin B.

  3. How to define green adjuvants.

    Science.gov (United States)

    Beck, Bert; Steurbaut, Walter; Spanoghe, Pieter

    2012-08-01

    The concept 'green adjuvants' is difficult to define. This paper formulates an answer based on two approaches. Starting from the Organisation for Economic Cooperation and Development (OECD) definition for green chemistry, production-based and environmental-impact-based definitions for green adjuvants are proposed. According to the production-based approach, adjuvants are defined as green if they are manufactured using renewable raw materials as much as possible while making efficient use of energy, preferably renewable energy. According to the environmental impact approach, adjuvants are defined as green (1) if they have a low human and environmental impact, (2) if they do not increase active ingredient environmental mobility and/or toxicity to humans and non-target organisms, (3) if they do not increase the exposure to these active substances and (4) if they lower the impact of formulated pesticides by enhancing the performance of active ingredients, thus potentially lowering the required dosage of active ingredients. Based on both approaches, a tentative definition for 'green adjuvants' is given, and future research and legislation directions are set out.

  4. CTOs at work

    CERN Document Server

    Donaldson, Scott; Donaldson, Gary

    2012-01-01

    Scott Donaldson, Stanley Siegel and Gary Donaldson interview many of the world's most influential chief technology officers in CTOs at Work, offering a brand-new companion volume to the highly acclaimed elite At Work books including Coders at Work, CIOS at Work and Venture Capitalists at Work. As the words "at work" suggest, the authors focus on how their interviewees tackle the day-to-day work of the CTO while revealing much more: how they got there, how they manage and allocate projects, and how they interact with business units and ensure that their companies take advantage of technologies,

  5. Authenticity at work

    NARCIS (Netherlands)

    van den Bosch, Ralph

    2016-01-01

    Authenticity at work, loosely defined as the degree to which an individual stays true to their core self, has impact on workers in the workplace. This thesis shows that authenticity at work can be measured with a reliable and valid instrument: the IAM Work. Furthermore, results of this thesis show t

  6. Authenticity at work

    NARCIS (Netherlands)

    van den Bosch, Ralph

    2016-01-01

    Authenticity at work, loosely defined as the degree to which an individual stays true to their core self, has impact on workers in the workplace. This thesis shows that authenticity at work can be measured with a reliable and valid instrument: the IAM Work. Furthermore, results of this thesis show

  7. UNIQLO, Define Your Own Fashion

    Institute of Scientific and Technical Information of China (English)

    Wang Ting

    2009-01-01

    @@ Yes,women like and enjoy shopping.Always,they want to buy some well-designed clothes with the most 'in'factors; and what's of the great importance,they would like to hear the words:"wow! You fit the wear well!"However,the most satisfied right things could not be always waiting for you there or you would not help complaining the so-fast changing trends day by day.At that time,why not to seek some delights from the basic classic collections?UNIQLO maybe is a choice for you to define your own fashion.

  8. Spent Fuel Working Group report on inventory and storage of the Department`s spent nuclear fuel and other reactor irradiated nuclear materials and their environmental, safety and health vulnerabilities. Volume 3, Site team reports

    Energy Technology Data Exchange (ETDEWEB)

    1993-11-01

    A self assessment was conducted of those Hanford facilities that are utilized to store Reactor Irradiated Nuclear Material, (RINM). The objective of the assessment is to identify the Hanford inventories of RINM and the ES & H concerns associated with such storage. The assessment was performed as proscribed by the Project Plan issued by the DOE Spent Fuel Working Group. The Project Plan is the plan of execution intended to complete the Secretary`s request for information relevant to the inventories and vulnerabilities of DOE storage of spent nuclear fuel. The Hanford RINM inventory, the facilities involved and the nature of the fuel stored are summarized. This table succinctly reveals the variety of the Hanford facilities involved, the variety of the types of RINM involved, and the wide range of the quantities of material involved in Hanford`s RINM storage circumstances. ES & H concerns are defined as those circumstances that have the potential, now or in the future, to lead to a criticality event, to a worker radiation exposure event, to an environmental release event, or to public announcements of such circumstances and the sensationalized reporting of the inherent risks.

  9. Determination of turnover and cushion gas volume of a prospected gas storage reservoir under uncertainty

    Energy Technology Data Exchange (ETDEWEB)

    Gubik, A. [RAG-AG Wien (Austria); Baffoe, J.; Schulze-Riegert, R. [SPT Group GmbH, Hamburg (Germany)

    2013-08-01

    Gas storages define a key contribution for building a reliable gas supply chain from production to consumers. In a competitive gas market with short reaction times to seasonal and other gas injection and extraction requirements, gas storages also receive a strong focus on availability and precise prediction estimates for future operation scenarios. Reservoir management workflows are increasingly built on reservoir simulation support for optimizing production schemes and estimating the impact of subsurface uncertainties on field development scenarios. Simulation models for gas storages are calibrated to geological data and accurate reproduction of historical production data are defined as a prerequisite for reliable production and performance forecasts. The underlying model validation process is called history matching, which potentially generates alternative simulation models due to prevailing geological uncertainties. In the past, a single basecase reference model was used to predict production capacities of a gas storage. The working gas volume was precisely defined over a contracted plateau delivery and the required cushion gas volume maintains the reservoir pressure during the operation. Cushion and working gas Volume are strongly dependent on reservoir parameters. In this work an existing depleted gas reservoir and the operation target as a gas storage is described. Key input data to the reservoir model description and simulation is reviewed including production history and geological uncertainties based on large well spacing, limited core and well data and a limited seismic resolution. Target delivery scenarios of the prospected gas storage are evaluated under uncertainty. As one key objective, optimal working gas and cushion gas volumes are described in a probabilistic context reflecting geological uncertainties. Several work steps are defined and included in an integrated workflow design. Equiprobable geological models are generated and evaluated based on

  10. Defining Life: The Virus Viewpoint

    Science.gov (United States)

    Forterre, Patrick

    2010-04-01

    Are viruses alive? Until very recently, answering this question was often negative and viruses were not considered in discussions on the origin and definition of life. This situation is rapidly changing, following several discoveries that have modified our vision of viruses. It has been recognized that viruses have played (and still play) a major innovative role in the evolution of cellular organisms. New definitions of viruses have been proposed and their position in the universal tree of life is actively discussed. Viruses are no more confused with their virions, but can be viewed as complex living entities that transform the infected cell into a novel organism—the virus—producing virions. I suggest here to define life (an historical process) as the mode of existence of ribosome encoding organisms (cells) and capsid encoding organisms (viruses) and their ancestors. I propose to define an organism as an ensemble of integrated organs (molecular or cellular) producing individuals evolving through natural selection. The origin of life on our planet would correspond to the establishment of the first organism corresponding to this definition.

  11. Defining life: the virus viewpoint.

    Science.gov (United States)

    Forterre, Patrick

    2010-04-01

    Are viruses alive? Until very recently, answering this question was often negative and viruses were not considered in discussions on the origin and definition of life. This situation is rapidly changing, following several discoveries that have modified our vision of viruses. It has been recognized that viruses have played (and still play) a major innovative role in the evolution of cellular organisms. New definitions of viruses have been proposed and their position in the universal tree of life is actively discussed. Viruses are no more confused with their virions, but can be viewed as complex living entities that transform the infected cell into a novel organism-the virus-producing virions. I suggest here to define life (an historical process) as the mode of existence of ribosome encoding organisms (cells) and capsid encoding organisms (viruses) and their ancestors. I propose to define an organism as an ensemble of integrated organs (molecular or cellular) producing individuals evolving through natural selection. The origin of life on our planet would correspond to the establishment of the first organism corresponding to this definition.

  12. Trading Volume Trend As the Investor’s Sentiment Indicator in Istanbul Stock Exchange = Trading Volume Trend As the Investor’s Sentiment Indicator in Istanbul Stock Exchange / İstanbul Menkul Kıymetler Borsasında Yatırımcı Duyarlılığı Göstergesi Olarak İşlem Hacmi Trendi

    Directory of Open Access Journals (Sweden)

    Oktay TAŞ

    2012-11-01

    Full Text Available This study relates the changes of trading volume to investor sentiment, and investigates its ability in predicting stock returns. Investor sentiment is the enthusiasm of irrational investors on an asset, relative to that of rational investors. Having investigated the effects of Investor Sentiment on Stock Prices, Baker and Stein argued that an increase in trading volume reflects a rise in investor sentiment, which can be defined as the change in trading volume per unit of time; called the trading volume trend, it can be used as a measure of investor sentiment on individual stocks. This work aims to find out the volume trend characteristics of all listed equities in the Istanbul Stock Exchange. Results suggest that almost all beta coefficients of volume trend values have positive signs, which reflects the positive contribution of volume changes on the corresponding stock returns.

  13. Does "grief work" work?

    NARCIS (Netherlands)

    Stroebe, M; Stroebe, W

    1991-01-01

    This article challenges the long-standing belief in the necessity of "grief work" for adjustment to bereavement. Evidence is offered from a prospective study of 30 widows and 30 widowers that indicates that grief work is not always as essential for adjustment to bereavement as theorists and clinicia

  14. Human Work Interaction Design

    DEFF Research Database (Denmark)

    Lopes, Arminda; Ørngreen, Rikke

    This book constitutes the thoroughly refereed post-conference proceedings of the Third IFIP WG 13.6 Working Conference on Human Work Interaction Design, HWID 2012, held in Copenhagen, Denmark, in December 2012. The 16 revised papers presented were carefully selected for inclusion in this volume...

  15. Software Defined Radios - Architectures, Systems and Functions

    Science.gov (United States)

    Sims, Herb

    2017-01-01

    Software Defined Radio is an industry term describing a method of utilizing a minimum amount of Radio Frequency (RF)/analog electronics before digitization takes place. Upon digitization all other functions are performed in software/firmware. There are as many different types of SDRs as there are data systems. Software Defined Radio (SDR) technology has been proven in the commercial sector since the early 90's. Today's rapid advancement in mobile telephone reliability and power management capabilities exemplifies the effectiveness of the SDR technology for the modern communications market. In contrast the foundations of transponder technology presently qualified for satellite applications were developed during the early space program of the 1960's. SDR technology offers potential to revolutionize satellite transponder technology by increasing science data through-put capability by at least an order of magnitude. While the SDR is adaptive in nature and is "One-size-fits-all" by design, conventional transponders are built to a specific platform and must be redesigned for every new bus. The SDR uses a minimum amount of analog/Radio Frequency components to up/down-convert the RF signal to/from a digital format. Once analog data is digitized, all processing is performed using hardware logic. Typical SDR processes include; filtering, modulation, up/down converting and demodulation. This presentation will show how the emerging SDR market has leveraged the existing commercial sector to provide a path to a radiation tolerant SDR transponder. These innovations will reduce the cost of transceivers, a decrease in power requirements and a commensurate reduction in volume. A second pay-off is the increased flexibility of the SDR by allowing the same hardware to implement multiple transponder types by altering hardware logic - no change of analog hardware is required - all of which can be ultimately accomplished in orbit. This in turn would provide high capability and low cost

  16. Topological dynamics and definable groups

    CERN Document Server

    Pillay, Anand

    2012-01-01

    Following the works of Newelski we continue the study of the relations between abstract topological dynamics and generalized stable group theory. We show that the Ellis theory, applied to the action of G(M) on its type space, for G an fsg group in a NIP theory, and M any model, yields the quotient G/G^00.

  17. Principals and SRO's: Defining Roles.

    Science.gov (United States)

    Bond, Bill

    2001-01-01

    Many principals have recently acquired school resource officers, police officers who are stationed in schools and report to local sheriffs or police chiefs. Working effectively with a resource officer requires that principals and officers understand each other's role and express partnership details in a memorandum of understanding. (MLH)

  18. Network Coded Software Defined Networking

    DEFF Research Database (Denmark)

    Hansen, Jonas; Roetter, Daniel Enrique Lucani; Krigslund, Jeppe

    2015-01-01

    Software defined networking has garnered large attention due to its potential to virtualize services in the Internet, introducing flexibility in the buffering, scheduling, processing, and routing of data in network routers. SDN breaks the deadlock that has kept Internet network protocols stagnant...... for decades, while applications and physical links have evolved. This article advocates for the use of SDN to bring about 5G network services by incorporating network coding (NC) functionalities. The latter constitutes a major leap forward compared to the state-of-the- art store and forward Internet paradigm....... The inherent flexibility of both SDN and NC provides fertile ground to envision more efficient, robust, and secure networking designs, which may also incorporate content caching and storage, all of which are key challenges of the upcoming 5G networks. This article not only proposes the fundamentals...

  19. Network Coded Software Defined Networking

    DEFF Research Database (Denmark)

    Krigslund, Jeppe; Hansen, Jonas; Roetter, Daniel Enrique Lucani;

    2015-01-01

    Software Defined Networking (SDN) and Network Coding (NC) are two key concepts in networking that have garnered a large attention in recent years. On the one hand, SDN's potential to virtualize services in the Internet allows a large flexibility not only for routing data, but also to manage...... buffering, scheduling, and processing over the network. On the other hand, NC has shown great potential for increasing robustness and performance when deployed on intermediate nodes in the network. This new paradigm changes the dynamics of network protocols, requiring new designs that exploit its potential....... This paper advocates for the use of SDN to bring about future Internet and 5G network services by incorporating network coding (NC) functionalities. The inherent flexibility of both SDN and NC provides a fertile ground to envision more efficient, robust, and secure networking designs, that may also...

  20. Miniature EVA Software Defined Radio

    Science.gov (United States)

    Pozhidaev, Aleksey

    2012-01-01

    As NASA embarks upon developing the Next-Generation Extra Vehicular Activity (EVA) Radio for deep space exploration, the demands on EVA battery life will substantially increase. The number of modes and frequency bands required will continue to grow in order to enable efficient and complex multi-mode operations including communications, navigation, and tracking applications. Whether conducting astronaut excursions, communicating to soldiers, or first responders responding to emergency hazards, NASA has developed an innovative, affordable, miniaturized, power-efficient software defined radio that offers unprecedented power-efficient flexibility. This lightweight, programmable, S-band, multi-service, frequency- agile EVA software defined radio (SDR) supports data, telemetry, voice, and both standard and high-definition video. Features include a modular design, an easily scalable architecture, and the EVA SDR allows for both stationary and mobile battery powered handheld operations. Currently, the radio is equipped with an S-band RF section. However, its scalable architecture can accommodate multiple RF sections simultaneously to cover multiple frequency bands. The EVA SDR also supports multiple network protocols. It currently implements a Hybrid Mesh Network based on the 802.11s open standard protocol. The radio targets RF channel data rates up to 20 Mbps and can be equipped with a real-time operating system (RTOS) that can be switched off for power-aware applications. The EVA SDR's modular design permits implementation of the same hardware at all Network Nodes concept. This approach assures the portability of the same software into any radio in the system. It also brings several benefits to the entire system including reducing system maintenance, system complexity, and development cost.

  1. Recommendations from gynaecological (GYN) GEC ESTRO working group (II): concepts and terms in 3D image-based treatment planning in cervix cancer brachytherapy-3D dose volume parameters and aspects of 3D image-based anatomy, radiation physics, radiobiology.

    Science.gov (United States)

    Pötter, Richard; Haie-Meder, Christine; Van Limbergen, Erik; Barillot, Isabelle; De Brabandere, Marisol; Dimopoulos, Johannes; Dumas, Isabelle; Erickson, Beth; Lang, Stefan; Nulens, An; Petrow, Peter; Rownd, Jason; Kirisits, Christian

    2006-01-01

    The second part of the GYN GEC ESTRO working group recommendations is focused on 3D dose-volume parameters for brachytherapy of cervical carcinoma. Methods and parameters have been developed and validated from dosimetric, imaging and clinical experience from different institutions (University of Vienna, IGR Paris, University of Leuven). Cumulative dose volume histograms (DVH) are recommended for evaluation of the complex dose heterogeneity. DVH parameters for GTV, HR CTV and IR CTV are the minimum dose delivered to 90 and 100% of the respective volume: D90, D100. The volume, which is enclosed by 150 or 200% of the prescribed dose (V150, V200), is recommended for overall assessment of high dose volumes. V100 is recommended for quality assessment only within a given treatment schedule. For Organs at Risk (OAR) the minimum dose in the most irradiated tissue volume is recommended for reporting: 0.1, 1, and 2 cm3; optional 5 and 10 cm3. Underlying assumptions are: full dose of external beam therapy in the volume of interest, identical location during fractionated brachytherapy, contiguous volumes and contouring of organ walls for >2 cm3. Dose values are reported as absorbed dose and also taking into account different dose rates. The linear-quadratic radiobiological model-equivalent dose (EQD2)-is applied for brachytherapy and is also used for calculating dose from external beam therapy. This formalism allows systematic assessment within one patient, one centre and comparison between different centres with analysis of dose volume relations for GTV, CTV, and OAR. Recommendations for the transition period from traditional to 3D image-based cervix cancer brachytherapy are formulated. Supplementary data (available in the electronic version of this paper) deals with aspects of 3D imaging, radiation physics, radiation biology, dose at reference points and dimensions and volumes for the GTV and CTV (adding to [Haie-Meder C, Pötter R, Van Limbergen E et al. Recommendations from

  2. Spent Fuel Working Group report on inventory and storage of the Department`s spent nuclear fuel and other reactor irradiated nuclear materials and their environmental, safety and health vulnerabilities. Volume 2, Working Group Assessment Team reports; Vulnerability development forms; Working group documents

    Energy Technology Data Exchange (ETDEWEB)

    1993-11-01

    The Secretary of Energy`s memorandum of August 19, 1993, established an initiative for a Department-wide assessment of the vulnerabilities of stored spent nuclear fuel and other reactor irradiated nuclear materials. A Project Plan to accomplish this study was issued on September 20, 1993 by US Department of Energy, Office of Environment, Health and Safety (EH) which established responsibilities for personnel essential to the study. The DOE Spent Fuel Working Group, which was formed for this purpose and produced the Project Plan, will manage the assessment and produce a report for the Secretary by November 20, 1993. This report was prepared by the Working Group Assessment Team assigned to the Hanford Site facilities. Results contained in this report will be reviewed, along with similar reports from all other selected DOE storage sites, by a working group review panel which will assemble the final summary report to the Secretary on spent nuclear fuel storage inventory and vulnerability.

  3. Sparse PDF Volumes for Consistent Multi-Resolution Volume Rendering

    KAUST Repository

    Sicat, Ronell Barrera

    2014-12-31

    This paper presents a new multi-resolution volume representation called sparse pdf volumes, which enables consistent multi-resolution volume rendering based on probability density functions (pdfs) of voxel neighborhoods. These pdfs are defined in the 4D domain jointly comprising the 3D volume and its 1D intensity range. Crucially, the computation of sparse pdf volumes exploits data coherence in 4D, resulting in a sparse representation with surprisingly low storage requirements. At run time, we dynamically apply transfer functions to the pdfs using simple and fast convolutions. Whereas standard low-pass filtering and down-sampling incur visible differences between resolution levels, the use of pdfs facilitates consistent results independent of the resolution level used. We describe the efficient out-of-core computation of large-scale sparse pdf volumes, using a novel iterative simplification procedure of a mixture of 4D Gaussians. Finally, our data structure is optimized to facilitate interactive multi-resolution volume rendering on GPUs.

  4. Sparse PDF Volumes for Consistent Multi-Resolution Volume Rendering.

    Science.gov (United States)

    Sicat, Ronell; Krüger, Jens; Möller, Torsten; Hadwiger, Markus

    2014-12-01

    This paper presents a new multi-resolution volume representation called sparse pdf volumes, which enables consistent multi-resolution volume rendering based on probability density functions (pdfs) of voxel neighborhoods. These pdfs are defined in the 4D domain jointly comprising the 3D volume and its 1D intensity range. Crucially, the computation of sparse pdf volumes exploits data coherence in 4D, resulting in a sparse representation with surprisingly low storage requirements. At run time, we dynamically apply transfer functions to the pdfs using simple and fast convolutions. Whereas standard low-pass filtering and down-sampling incur visible differences between resolution levels, the use of pdfs facilitates consistent results independent of the resolution level used. We describe the efficient out-of-core computation of large-scale sparse pdf volumes, using a novel iterative simplification procedure of a mixture of 4D Gaussians. Finally, our data structure is optimized to facilitate interactive multi-resolution volume rendering on GPUs.

  5. Solar central receiver prototype heliostat CDRL item B. d. Final technical report, Volume 2

    Energy Technology Data Exchange (ETDEWEB)

    Easton, C. R.

    1978-08-01

    This is volume II of a two volume report which presents the results of a study to define a low-cost approach to the production, installation, and operation of heliostats for central receiver solar thermal power plants. Performance and cost analyses are presented, and critical R and D areas are identified. Also, computer printed work sheets are included for heliostat investment, maintenance equipment investment, initial spares investment, and first years operations and maintenance for 2,500, 25,000, 250,000, and 1,000,000 units per year production. (WHK)

  6. Software Defined Common Processing System (SDCPS) Project

    Data.gov (United States)

    National Aeronautics and Space Administration — Coherent Logix, Incorporated proposes the Software Defined Common Processing System (SDCPS) program to facilitate the development of a Software Defined Radio...

  7. Future Scenarios for Software-Defined Metro and Access Networks and Software-Defined Photonics

    Directory of Open Access Journals (Sweden)

    Tommaso Muciaccia

    2017-01-01

    Full Text Available In recent years, architectures, devices, and components in telecommunication networks have been challenged by evolutionary and revolutionary factors which are drastically changing the traffic features. Most of these changes imply the need for major re-configurability and programmability not only in data-centers and core networks, but also in the metro-access segment. In a wide variety of contexts, this necessity has been addressed by the proposed introduction of the innovative paradigm of software-defined networks (SDNs. Several solutions inspired by the SDN model have been recently proposed also for metro and access networks, where the adoption of a new generation of software-defined reconfigurable integrated photonic devices is highly desirable. In this paper, we review the possible future application scenarios for software-defined metro and access networks and software-defined photonics (SDP, on the base of analytics, statistics, and surveys. This work describes the reasons underpinning the presented radical change of paradigm and summarizes the most significant solutions proposed in literature, with a specific emphasis to physical-layer reconfigurable networks and a focus on both architectures and devices.

  8. Defining excellence in vascular neurosurgery.

    Science.gov (United States)

    Sanai, Nader; Spetzler, Robert F

    2010-01-01

    Success as a vascular neurosurgeon almost always begins with passion, an inherent love for the work that drives an insatiable desire for personal improvement. A personal definition of excellence in vascular neurosurgery includes several fundamental qualities: mastery of the basics, refinement of technique, advancement of technology, investigative study, advanced decision making, microsurgical innovation, a well-rounded surgical armamentarium, and a lifelong commitment to teaching. Ultimately, the reward for these efforts is the ability to influence generations to come, particularly as one follows the rising careers of former trainees, each redefining the term "excellence" in vascular neurosurgery.

  9. Cancer nursing in Ontario: defining nursing roles.

    Science.gov (United States)

    Fitch, Margaret I; Mings, Deborah

    2003-01-01

    The delivery of cancer care in Ontario is facing unprecedented challenges. Shortages in nursing, as in all professional disciplines, are having an impact on the delivery of cancer care. Oncology nurses have a major role to play in the delivery of optimum cancer care. Oncology nursing, when adequately defined and supported, can benefit the cancer delivery system, patients, and families. A primary nursing model is seen as being key to the delivery of optimum cancer care. Primary nursing as a philosophy facilitates continuity of care, coordination of a patient's care plan, and a meaningful ongoing relationship with the patient and his/her family. Primary nursing, when delivered in the collaboration of a nurse-physician team, allows for medical resources to be used appropriately. Defined roles enable nurses to manage patients within their scope of practice in collaboration with physicians. Enacting other nursing roles, such as nurse practitioners and advanced practice nurses, can also enable the health care system to manage a broader number of patients with more complex needs. This article presents a position paper originally written as the basis for an advocacy and education initiative in Ontario. It is shared in anticipation that the work may be useful to oncology nurses in other jurisdictions in their efforts to advance oncology nursing and improvement of patient care.

  10. "Defining Computer 'Speed': An Unsolved Challenge"

    CERN Document Server

    CERN. Geneva

    2012-01-01

    Abstract: The reason we use computers is their speed, and the reason we use parallel computers is that they're faster than single-processor computers. Yet, after 70 years of electronic digital computing, we still do not have a solid definition of what computer 'speed' means, or even what it means to be 'faster'. Unlike measures in physics, where the definition of speed is rigorous and unequivocal, in computing there is no definition of speed that is universally accepted. As a result, computer customers have made purchases misguided by dubious information, computer designers have optimized their designs for the wrong goals, and computer programmers have chosen methods that optimize the wrong things. This talk describes why some of the obvious and historical ways of defining 'speed' haven't served us well, and the things we've learned in the struggle to find a definition that works. Biography: Dr. John Gustafson is a Director ...

  11. Reconfigurable, Cognitive Software-Defined Radio

    Science.gov (United States)

    Bhat, Arvind

    2015-01-01

    Software-defined radio (SDR) technology allows radios to be reconfigured to perform different communication functions without using multiple radios to accomplish each task. Intelligent Automation, Inc., has developed SDR platforms that switch adaptively between different operation modes. The innovation works by modifying both transmit waveforms and receiver signal processing tasks. In Phase I of the project, the company developed SDR cognitive capabilities, including adaptive modulation and coding (AMC), automatic modulation recognition (AMR), and spectrum sensing. In Phase II, these capabilities were integrated into SDR platforms. The reconfigurable transceiver design employs high-speed field-programmable gate arrays, enabling multimode operation and scalable architecture. Designs are based on commercial off-the-shelf (COTS) components and are modular in nature, making it easier to upgrade individual components rather than redesigning the entire SDR platform as technology advances.

  12. Nurse leader resilience: career defining moments.

    Science.gov (United States)

    Cline, Susan

    2015-01-01

    Resilience is an essential component of effective nursing leadership. It is defined as the ability to survive and thrive in the face of adversity. Resilience can be developed and internalized as a measure to improve retention and reduce burnout. Nurse leaders at all levels should develop these competencies to survive and thrive in an increasingly complex health care environment. Building positive relationships, maintaining positivity, developing emotional insight, creating work-life balance, and reflecting on successes and challenges are effective strategies for resilience building. Nurse leaders have a professional obligation to develop resilience in themselves, the teams they supervise, and the organization as a whole. Additional benefits include reduced turnover, reduced cost, and improved quality outcomes through organizational mindfulness.

  13. Bohr's way to defining complementarity

    CERN Document Server

    De Gregorio, Alberto

    2014-01-01

    We shall go through Bohr's talk about complementary features of quantum theory at the Volta Conference in September 1927, by collating a manuscript that Bohr wrote in Como with the unpublished stenographic report of his talk. We shall conclude - also with the help of some unpublished letters - that Bohr gave a very concise speech in September. Only at the fifth Solvay Meeting, in Bruxelles in October, did he make in public a substantial exposition of his ideas. The unpublished stenographic report of the Solvay Conference adds more detail to Bohr's working out of his 1928 papers. Our conclusion is that discussions with colleagues had a decisive role for Bohr and his final presentation of complementary sides of atomic physics.

  14. Definability in the Real Universe

    CERN Document Server

    Cooper, S Barry

    2011-01-01

    Logic has its origins in basic questions about the nature of the real world and how we describe it. This article seeks to bring out the physical and epistemological relevance of some of the more recent technical work in logic and computability theory. "If you are receptive and humble, mathematics will lead you by the hand. Again and again, when I have been at a loss how to proceed, I have just had to wait until I have felt the mathematics lead me by the hand. It has led me along an unexpected path, a path where new vistas open up, a path leading to new territory, where one can set up a base of operations, from which one can survey the surroundings and plan future progress." - Paul Dirac, 27 November, 1975. In Paul A. M. Dirac Papers, Florida State University Libraries, Tallahassee, Florida, USA, No. 2/29/17.

  15. Sintering as a process of transport of activated volume

    Directory of Open Access Journals (Sweden)

    Nikolić Nataša S.

    2002-01-01

    Full Text Available Starting with the fact that sintering is the consequence of the process of transport of activated volume, it has been shown how the kinetics of the sintering process can be defined. The activated volume was in principle defined as a parameter which describes a system’s deffectivity on an atomic level.

  16. Neural Anatomy of Primary Visual Cortex Limits Visual Working Memory.

    Science.gov (United States)

    Bergmann, Johanna; Genç, Erhan; Kohler, Axel; Singer, Wolf; Pearson, Joel

    2016-01-01

    Despite the immense processing power of the human brain, working memory storage is severely limited, and the neuroanatomical basis of these limitations has remained elusive. Here, we show that the stable storage limits of visual working memory for over 9 s are bound by the precise gray matter volume of primary visual cortex (V1), defined by fMRI retinotopic mapping. Individuals with a bigger V1 tended to have greater visual working memory storage. This relationship was present independently for both surface size and thickness of V1 but absent in V2, V3 and for non-visual working memory measures. Additional whole-brain analyses confirmed the specificity of the relationship to V1. Our findings indicate that the size of primary visual cortex plays a critical role in limiting what we can hold in mind, acting like a gatekeeper in constraining the richness of working mental function.

  17. Animal innovation defined and operationalized.

    Science.gov (United States)

    Ramsey, Grant; Bastian, Meredith L; van Schaik, Carel

    2007-08-01

    Innovation is a key component of most definitions of culture and intelligence. Additionally, innovations may affect a species' ecology and evolution. Nonetheless, conceptual and empirical work on innovation has only recently begun. In particular, largely because the existing operational definition (first occurrence in a population) requires long-term studies of populations, there has been no systematic study of innovation in wild animals. To facilitate such study, we have produced a new definition of innovation: Innovation is the process that generates in an individual a novel learned behavior that is not simply a consequence of social learning or environmental induction. Using this definition, we propose a new operational approach for distinguishing innovations in the field. The operational criteria employ information from the following sources: (1) the behavior's geographic and local prevalence and individual frequency; (2) properties of the behavior, such as the social role of the behavior, the context in which the behavior is exhibited, and its similarity to other behaviors; (3) changes in the occurrence of the behavior over time; and (4) knowledge of spontaneous or experimentally induced behavior in captivity. These criteria do not require long-term studies at a single site, but information from multiple populations of a species will generally be needed. These criteria are systematized into a dichotomous key that can be used to assess whether a behavior observed in the field is likely to be an innovation.

  18. Development of a methodology for defining whole-building energy design targets for commercial buildings: Phase 2, Development concept stage report

    Energy Technology Data Exchange (ETDEWEB)

    Jones, J.W. (American Society of Heating, Refrigerating and Air-Conditioning Engineers, Inc., Atlanta, GA (USA)); Deringer, J.J. (American Inst. of Architects, Washington, DC (USA)); McKay, H.N. (Illuminating Engineering Society of North America, New York, NY (USA))

    1990-09-01

    Since 1985, the Pacific Northwest Laboratory (PNL) has managed the Whole-Building Energy Design Targets project for the US Department of Energy (DOE) Office of Building Technologies (formerly the Office of Buildings and Community Systems). The primary focus of the Targets project is to develop a flexible methodology for buildings industry use in setting energy performance guidelines for commercial buildings and for determining compliance with those guidelines. The project is being conducted as a two-phase effort. In Phase 1, Planning, the project team determined the research that was necessary for developing the Targets methodology. In the concept stage of Phase 2, Development, the team sought to define the technical and software development concepts upon which the overall Targets methodology will be based. The concept stage work is documented in four volumes, of which this summary volume is the first. The three other volumes are Volume 2: Technical Concept Development Task Reports, Volume 3: Workshop Summaries, and Volume 4: Software Concept Development Task Reports. 8 refs., 14 figs.

  19. Defining secondary progressive multiple sclerosis.

    Science.gov (United States)

    Lorscheider, Johannes; Buzzard, Katherine; Jokubaitis, Vilija; Spelman, Tim; Havrdova, Eva; Horakova, Dana; Trojano, Maria; Izquierdo, Guillermo; Girard, Marc; Duquette, Pierre; Prat, Alexandre; Lugaresi, Alessandra; Grand'Maison, François; Grammond, Pierre; Hupperts, Raymond; Alroughani, Raed; Sola, Patrizia; Boz, Cavit; Pucci, Eugenio; Lechner-Scott, Jeanette; Bergamaschi, Roberto; Oreja-Guevara, Celia; Iuliano, Gerardo; Van Pesch, Vincent; Granella, Franco; Ramo-Tello, Cristina; Spitaleri, Daniele; Petersen, Thor; Slee, Mark; Verheul, Freek; Ampapa, Radek; Amato, Maria Pia; McCombe, Pamela; Vucic, Steve; Sánchez Menoyo, José Luis; Cristiano, Edgardo; Barnett, Michael H; Hodgkinson, Suzanne; Olascoaga, Javier; Saladino, Maria Laura; Gray, Orla; Shaw, Cameron; Moore, Fraser; Butzkueven, Helmut; Kalincik, Tomas

    2016-09-01

    A number of studies have been conducted with the onset of secondary progressive multiple sclerosis as an inclusion criterion or an outcome of interest. However, a standardized objective definition of secondary progressive multiple sclerosis has been lacking. The aim of this work was to evaluate the accuracy and feasibility of an objective definition for secondary progressive multiple sclerosis, to enable comparability of future research studies. Using MSBase, a large, prospectively acquired, global cohort study, we analysed the accuracy of 576 data-derived onset definitions for secondary progressive multiple sclerosis and first compared these to a consensus opinion of three neurologists. All definitions were then evaluated against 5-year disease outcomes post-assignment of secondary progressive multiple sclerosis: sustained disability, subsequent sustained progression, positive disability trajectory, and accumulation of severe disability. The five best performing definitions were further investigated for their timeliness and overall disability burden. A total of 17 356 patients were analysed. The best definition included a 3-strata progression magnitude in the absence of a relapse, confirmed after 3 months within the leading Functional System and required an Expanded Disability Status Scale step ≥4 and pyramidal score ≥2. It reached an accuracy of 87% compared to the consensus diagnosis. Seventy-eight per cent of the identified patients showed a positive disability trajectory and 70% reached significant disability after 5 years. The time until half of all patients were diagnosed was 32.6 years (95% confidence interval 32-33.6) after disease onset compared with the physicians' diagnosis at 36 (35-39) years. The identified patients experienced a greater disease burden [median annualized area under the disability-time curve 4.7 (quartiles 3.6, 6.0)] versus non-progressive patients [1.8 (1.2, 1.9)]. This objective definition of secondary progressive multiple

  20. Thermodynamic volume of cosmological solitons

    Science.gov (United States)

    Mbarek, Saoussen; Mann, Robert B.

    2017-02-01

    We present explicit expressions of the thermodynamic volume inside and outside the cosmological horizon of Eguchi-Hanson solitons in general odd dimensions. These quantities are calculable and well-defined regardless of whether or not the regularity condition for the soliton is imposed. For the inner case, we show that the reverse isoperimetric inequality is not satisfied for general values of the soliton parameter a, though a narrow range exists for which the inequality does hold. For the outer case, we find that the mass Mout satisfies the maximal mass conjecture and the volume is positive. We also show that, by requiring Mout to yield the mass of dS spacetime when the soliton parameter vanishes, the associated cosmological volume is always positive.

  1. Thermodynamic Volume of Cosmological Solitons

    CERN Document Server

    Mbarek, Saoussen

    2016-01-01

    We present explicit expressions of the thermodynamic volume inside and outside the cosmological horizon of Eguchi-Hanson solitons in general odd dimensions. These quantities are calculable and well-defined regardless of whether or not the regularity condition for the soliton is imposed. For the inner case, we show that the reverse isoperimetric inequality is not satisfied for general values of the soliton parameter $a$, though a narrow range exists for which the inequality does hold. For the outer case, we find that the mass $M_{out}$ satisfies the maximal mass conjecture and the volume is positive. We also show that, by requiring $M_{out}$ to yield the mass of dS spacetime when the soliton parameter vanishes, the associated cosmological volume is always positive.

  2. Mixed Waste Working Group report

    Energy Technology Data Exchange (ETDEWEB)

    1993-11-09

    The treatment of mixed waste remains one of this country`s most vexing environmental problems. Mixed waste is the combination of radioactive waste and hazardous waste, as defined by the Resource Conservation and Recovery Act (RCRA). The Department of Energy (DOE), as the country`s largest mixed waste generator, responsible for 95 percent of the Nation`s mixed waste volume, is now required to address a strict set of milestones under the Federal Facility Compliance Act of 1992. DOE`s earlier failure to adequately address the storage and treatment issues associated with mixed waste has led to a significant backlog of temporarily stored waste, significant quantities of buried waste, limited permanent disposal options, and inadequate treatment solutions. Between May and November of 1993, the Mixed Waste Working Group brought together stakeholders from around the Nation. Scientists, citizens, entrepreneurs, and bureaucrats convened in a series of forums to chart a course for accelerated testing of innovative mixed waste technologies. For the first time, a wide range of stakeholders were asked to examine new technologies that, if given the chance to be tested and evaluated, offer the prospect for better, safer, cheaper, and faster solutions to the mixed waste problem. In a matter of months, the Working Group has managed to bridge a gap between science and perception, engineer and citizen, and has developed a shared program for testing new technologies.

  3. Volume-effect in radiation therapy part one: volume-effect and tumour; L'effet volume en radiotherapie premiere partie: effet volume et tumeur

    Energy Technology Data Exchange (ETDEWEB)

    Huchet, A.; Wu, J. [Hopital Europeen Georges-Pompidou (AP-HP), Service de Radiotherapie, 75 - Paris (France); Caudry, M.; Trouette, R.; Vendrely, V.; Causse, N.; Recaldini, L.; Dahan, O.; Maire, J.P. [Hopital Saint-Andre, Service de Radiotherapie, 33 - Bordeaux (France); Belkacemi, Y. [Centre de Lutte Contre le Cancer Oscar-Lambret, Dept. de Radiotherapie, 59 - Lille (France)

    2003-04-01

    Volume is an important parameter of radiation therapy. Local control is inversely related to tumor size and the complication rate increases with the importance of the irradiated volume. Although the effect of irradiated volume has been widely reported since the beginning of radiotherapy, it has been less studied than other radiation parameters such as dose, fractionation, or treatment duration. One of the first organ system in which the adverse effect of increased volume was well defined is the skin. Over the last twenty years, numerous mathematical models have been developed for different organs. In this report we will discuss the relation between irradiated volume and tumor control. In a second article we will study the impact of irradiated volume on radiation adverse effects. (authors)

  4. On defining semantics of extended attribute grammars

    DEFF Research Database (Denmark)

    Madsen, Ole Lehrmann

    1980-01-01

    Knuth has introduced attribute grammars (AGs) as a tool to define the semanitcs of context-free languages. The use of AGs in connection with programming language definitions has mostly been to define the context-sensitive syntax of the language and to define a translation in code for a hypothetical...

  5. Defining moments in leadership character development.

    Science.gov (United States)

    Bleich, Michael R

    2015-06-01

    Critical moments in life define one's character and clarify true values. Reflective leadership is espoused as an important practice for transformational leaders. Professional development educators can help surface and explore defining moments, strengthen leadership behavior with defining moments as a catalyst for change, and create safe spaces for leaders to expand their leadership capacity.

  6. Volumetric measurement of tank volume

    Science.gov (United States)

    Walter, Richard T. (Inventor); Vanbuskirk, Paul D. (Inventor); Weber, William F. (Inventor); Froebel, Richard C. (Inventor)

    1991-01-01

    A method is disclosed for determining the volume of compressible gas in a system including incompressible substances in a zero-gravity environment consisting of measuring the change in pressure (delta P) for a known volume change rate (delta V/delta t) in the polytrophic region between isothermal and adiabatic conditions. The measurements are utilized in an idealized formula for determining the change in isothermal pressure (delta P sub iso) for the gas. From the isothermal pressure change (delta iso) the gas volume is obtained. The method is also applicable to determination of gas volume by utilizing work (W) in the compression process. In a passive system, the relationship of specific densities can be obtained.

  7. Community biomass handbook volume 4: enterprise development for integrated wood manufacturing

    Science.gov (United States)

    Eini Lowell; D.R. Becker; D. Smith; M. Kauffman; D. Bihn

    2017-01-01

    The Community Biomass Handbook Volume 4: Enterprise Development for Integrated Wood Manufacturing is a guide for creating sustainable business enterprises using small diameter logs and biomass. This fourth volume is a companion to three Community Biomass Handbook volumes: Volume 1: Thermal Wood Energy; Volume 2: Alaska, Where Woody Biomass Can Work; and Volume 3: How...

  8. High Resolution Software Defined Radar System for Target Detection

    Directory of Open Access Journals (Sweden)

    S. Costanzo

    2013-01-01

    Full Text Available The Universal Software Radio Peripheral USRP NI2920, a software defined transceiver so far mainly used in Software Defined Radio applications, is adopted in this work to design a high resolution L-Band Software Defined Radar system. The enhanced available bandwidth, due to the Gigabit Ethernet interface, is exploited to obtain a higher slant-range resolution with respect to the existing Software Defined Radar implementations. A specific LabVIEW application, performing radar operations, is discussed, and successful validations are presented to demonstrate the accurate target detection capability of the proposed software radar architecture. In particular, outdoor and indoor test are performed by adopting a metal plate as reference structure located at different distances from the designed radar system, and results obtained from the measured echo are successfully processed to accurately reveal the correct target position, with the predicted slant-range resolution equal to 6 m.

  9. Chemically Defined Medium and Caenorhabditis elegans: A Powerful Approach

    Science.gov (United States)

    Szewczyk, N. J.; Kozak, E.; Conley, C. A.

    2003-01-01

    C. elegans has been established as a powerful genetic system. Growth in a chemically defined medium (C. elegans Maintenance Medium (CeMM)) now allows standardization and systematic manipulation of the nutrients that animals receive. Liquid cultivation allows automated culturing and experimentation and should be of me in large-scale growth and screening of animals. Here we present our initial results from developing culture systems with CeMM. We find that CeMM is versatile and culturing is simple. CeMM can be used in a solid or liquid state, it can be stored unused for at least a year, unattended actively growing cultures may be maintained longer than with standard techniques, and standard C. elegans protocols work well with animals grown in defined medium. We also find that there are caveats of using defined medium. Animals in defined medium grow more slowly than on standard medium, appear to display adaptation to the defined medium, and display altered growth rates as they change defined medium composition. As was suggested with the introduction of C. elegans as a potential genetic system, use of defined medium with C. elegans should prove a powerful tool.

  10. CREATIVITY AND INNOVATION AS DEFINED BY WORKER

    Directory of Open Access Journals (Sweden)

    Sônia Maria Guedes Gondim

    2015-12-01

    Full Text Available ABSTRACT Creativity and innovation are now required given the new configurations in work processes, in organizational formats, in physical and intangible technologies, as well as in products and markets. In parallel with the growing centrality and interest in the phenomena of creativity and innovation, a broadening of its concepts is observed. The inflation and trivialization of uses tend to make them self-explanatory and not very enlightening regarding situations to which they apply and the associated effects. The lack of conceptual clarity thus contributes both to undermining policies to promote creativity and innovation in organizations, as well as to hinder the employees' adherence to such policies. The study aimed to characterize the key elements of workers' informal definitions of creativity and innovation, and identify their alignment with definitions and theoretical perspectives. The study included 231 workers from Portuguese-, Spanish-, and Basque-speaking countries, aged 22-75 years. The qualitative data analysis software ATLAS.ti 7 was used for coding and categorization. One point of convergence with the specialized literature was that creativity and innovation strongly associated with novelty in the development of an idea / product / process / service. Creativity, however, is defined more in terms of dispositional factors rather than contextual and situational factors, diverging from current theoretical perspectives. Planning as a key aspect for organizational innovation development is practically absent from the workers' definitions. It discusses some impacts of these settings for organizational management practices.

  11. Editorial, Volume 5, Issue 1

    Directory of Open Access Journals (Sweden)

    Kristy L. Archuleta

    2014-08-01

    Full Text Available Welcome to Volume 5, Issue 1 of the Journal of Financial Therapy! In this issue, four scholarly papers are presented along with two profiles and a book review. These four papers address very important issues, such as mental health therapists’ competency in working with financial issues, financial stress of college students, parental messages about money, and financial advice media.

  12. Fractional watt Vuillemier cryogenic refrigerator program engineering notebook. Volume 1: Thermal analysis

    Science.gov (United States)

    Miller, W. S.

    1974-01-01

    The cryogenic refrigerator thermal design calculations establish design approach and basic sizing of the machine's elements. After the basic design is defined, effort concentrates on matching the thermodynamic design with that of the heat transfer devices (heat exchangers and regenerators). Typically, the heat transfer device configurations and volumes are adjusted to improve their heat transfer and pressure drop characteristics. These adjustments imply that changes be made to the active displaced volumes, compensating for the influence of the heat transfer devices on the thermodynamic processes of the working fluid. Then, once the active volumes are changed, the heat transfer devices require adjustment to account for the variations in flows, pressure levels, and heat loads. This iterative process is continued until the thermodynamic cycle parameters match the design of the heat transfer devices. By examing several matched designs, a near-optimum refrigerator is selected.

  13. A stencil-like volume of fluid (VOF) method for tracking free interface

    Institute of Scientific and Technical Information of China (English)

    LI Xiao-wei; FAN Jun-fei

    2008-01-01

    A stencil-like volume of fluid (VOF) method is proposed for tracking free interface. A stencil on a grid cell is worked out according to the normal direction of the interface, in which only three interface positions are possible in 2D cases, and the interface can be reconstructed by only requiring the known local volume fraction information. On the other hand, the fluid-occupying-length is defined on each side of the stencil, through which a unified fluid-occupying volume model and a unified algorithm can be obtained to solve the interface advection equation. The method is suitable for the arbitrary geometry of the grid cell, and is extendible to 3D cases. Typical numerical examples show that the current method can give "sharp" results for tracking free interface.

  14. Meaning in Work Life

    DEFF Research Database (Denmark)

    Ravn, Ib

    meaningful is still lacking (Harpaz & Fu, 2002), as are definitions of key terms. Here, I define meaning as the experience that something fits into a wider context or coheres within a larger whole.     I conceptualize meaning in work life as deriving from four factors, each of which helps us contribute...... to something larger than ourselves (Seligman, 2002) through our work. Thus, a person experiences meaning in work life when she... A. is able to use her signature strengths at work (Peterson and Seligman, 2004), B. makes an important contribution to the workplace (Drucker, 1999), C. participates in a productive...

  15. System technology analysis of aeroassisted orbital transfer vehicles: Moderate lift/drag (0.75-1.5). Volume 3: Cost estimates and work breakdown structure/dictionary, phase 1 and 2

    Science.gov (United States)

    1985-01-01

    Technology payoffs of representative ground based (Phase 1) and space based (Phase 2) mid lift/drag ratio aeroassisted orbit transfer vehicles (AOTV) were assessed and prioritized. A narrative summary of the cost estimates and work breakdown structure/dictionary for both study phases is presented. Costs were estimated using the Grumman Space Programs Algorithm for Cost Estimating (SPACE) computer program and results are given for four AOTV configurations. The work breakdown structure follows the standard of the joint government/industry Space Systems Cost Analysis Group (SSCAG). A table is provided which shows cost estimates for each work breakdown structure element.

  16. The LOLITA User-Definable Template Interface

    OpenAIRE

    Košmelj, Katarina

    2001-01-01

    The development of user-definable templates interfaces which allow the user to design new templates definitions in a user-friendly way is a new issue in the field of information extraction. The LOLITA user-definable templates interface allows the user to define new templates using sentences in natural language text with a few restrictions and formal elements. This approach is rather different from previous approaches to information extraction which require developers to code the template defi...

  17. Software Defined Common Processing System (SDCPS) Project

    Data.gov (United States)

    National Aeronautics and Space Administration — Coherent Logix, Incorporated (CLX) proposes the development of a Software Defined Common Processing System (SDCPS) that leverages the inherent advantages of an...

  18. Externally definable sets and dependent pairs II

    CERN Document Server

    Chernikov, Artem

    2012-01-01

    We continue investigating the structure of externally definable sets in NIP theories and preservation of NIP after expanding by new predicates. Most importantly: types over finite sets are uniformly definable; over a model, a family of non-forking instances of a formula (with parameters ranging over a type-definable set) can be covered with finitely many invariant types; we give some criteria for the boundedness of an expansion by a new predicate in a distal theory; naming an arbitrary small indiscernible sequence preserves NIP, while naming a large one doesn't; there are models of NIP theories over which all 1-types are definable, but not all n-types.

  19. Mobility Work

    DEFF Research Database (Denmark)

    Bardram, Jakob Eyvind; Bossen, Claus

    2005-01-01

    We posit the concept of Mobility Work to describe efforts of moving about people and things as part of accomplishing tasks. Mobility work can be seen as a spatial parallel to the concept of articulation work proposed by the sociologist Anselm Strauss. Articulation work describes efforts...... of coordination necessary in cooperative work, but focuses, we argue, mainly on the temporal aspects of cooperative work. As a supplement, the concept of mobility work focuses on the spatial aspects of cooperative work. Whereas actors seek to diminish the amount of articulation work needed in collaboration...... by constructing Standard Operation Procedures (SOPs), actors minimise mobility work by constructing Standard Operation Configurations (SOCs). We apply the concept of mobility work to the ethnography of hospital work, and argue that mobility arises because of the need to get access to people, places, knowledge and...

  20. Defining infidelity in research and couple counseling: a qualitative study.

    Science.gov (United States)

    Moller, Naomi P; Vossler, Andreas

    2015-01-01

    Infidelity can destroy relationships, but there is long-standing debate in the field about how best to define the construct. A clear definition of infidelity is important theoretically, empirically, and therapeutically; however, research on the topic is limited. This study explores how seven experienced couple counselors define infidelity on the basis of their work with heterosexual couples presenting with this issue. Thematic analysis was used to analyze interview transcripts and research findings suggest a rich web of conflicting definitions of infidelity for couples counselors and, in their accounts, clients. The findings support an understanding of infidelity as socially constructed and the implications of this for the field are discussed.

  1. Design and construction of a flat-panel-based cone beam volume computed tomography (FPD-CBVCT) imaging system through the adaptation of a commercially available CT system: work in progress

    Science.gov (United States)

    Conover, David L.; Ning, Ruola; Yu, Rongfeng; Zhong, Junmei

    2003-06-01

    The purpose of this presentation is to show how a commercially available spiral CT can be modified for use as the electro-mechanical scanner hardware for a prototype flat panel detector-based cone beam volume computed tomography (FPD-CBVCT) imaging system. FPD-CBVCT has the benefits of isotropic high resolution, low contrast sensitivity and 3D visualization. In contrast to spiral CT, which acquires a series of narrow slices, FPD-CBVCT acquires a full volume of data (limited by the cone angle and the FPD active area) in one radiographic subsystems to be controlled include: gantry rotation and tilt, patient table positioning, rotor control, mA control, the high frequency generator (kVp, exposure time, repetition rate) and image data acquisition. Also, a 2D full field FPD needs to replace the 1D detector, as well as the existing slit collimator needs to be retrofitted to a full field collimator to allow x-ray exposure over the entire active area of the FPD. In addition, x-ray projection data acquisition needs to be performed at >=30 fps. Power and communication signals to control modules on the rotating part of the gantry will be through integrated slip rings on the gantry. Through the synchronized control of the pulsed x-ray exposures, data acquisition, gantry rotation and tilt, as well as the position and translation speed of the patient table, the system will be able to achieve spiral cone beam and circle-plus-arc cone beam image acquisition protocols. Performance will be evaluated with optical encoders, standard dosimetry equipment and phantom studies.

  2. Defining orthologs and pangenome size metrics.

    Science.gov (United States)

    Bosi, Emanuele; Fani, Renato; Fondi, Marco

    2015-01-01

    Since the advent of ultra-massive sequencing techniques, the consequent drop-off in both price and time required made feasible the sequencing of increasingly more genomes from microbes belonging to the same taxonomic unit. Eventually, this led to the concept of pangenome, that is, the entire set of genes present in a group of representatives of the same genus/species, which, in turn, can be divided into core genome, defined as the set of those genes present in all the genomes under study, and a dispensable genome, the set of genes possessed only by one or a subset of organism. When analyzing a pangenome, an interesting point is to measure its size, thus estimating the gene repertoire of a given taxonomic group. This is usually performed counting the novel genes added to the overall pangenome when new genomes are sequenced and annotated. A pangenome can be also classified as open or close: in an open pangenome its size increases indefinitely when adding new genomes; thus sequencing additional strains will likely yield novel genes. Conversely, in a close pangenome, adding new genomes will not lead to the discovery of new coding capabilities. A central point in pangenomics is the definition of homology relationships between genes belonging to different genomes. This may turn into the search of those genes with similar sequences between different organisms (and including both paralogous and orthologous genes). In this chapter, methods for finding groups of orthologs between genomes and for estimating the pangenome size are discussed. Also, working codes to address these tasks are provided.

  3. Defining the critical hurdles in cancer immunotherapy

    Directory of Open Access Journals (Sweden)

    Fox Bernard A

    2011-12-01

    Full Text Available Abstract Scientific discoveries that provide strong evidence of antitumor effects in preclinical models often encounter significant delays before being tested in patients with cancer. While some of these delays have a scientific basis, others do not. We need to do better. Innovative strategies need to move into early stage clinical trials as quickly as it is safe, and if successful, these therapies should efficiently obtain regulatory approval and widespread clinical application. In late 2009 and 2010 the Society for Immunotherapy of Cancer (SITC, convened an "Immunotherapy Summit" with representatives from immunotherapy organizations representing Europe, Japan, China and North America to discuss collaborations to improve development and delivery of cancer immunotherapy. One of the concepts raised by SITC and defined as critical by all parties was the need to identify hurdles that impede effective translation of cancer immunotherapy. With consensus on these hurdles, international working groups could be developed to make recommendations vetted by the participating organizations. These recommendations could then be considered by regulatory bodies, governmental and private funding agencies, pharmaceutical companies and academic institutions to facilitate changes necessary to accelerate clinical translation of novel immune-based cancer therapies. The critical hurdles identified by representatives of the collaborating organizations, now organized as the World Immunotherapy Council, are presented and discussed in this report. Some of the identified hurdles impede all investigators; others hinder investigators only in certain regions or institutions or are more relevant to specific types of immunotherapy or first-in-humans studies. Each of these hurdles can significantly delay clinical translation of promising advances in immunotherapy yet if overcome, have the potential to improve outcomes of patients with cancer.

  4. Defining indicators to motorize block valves aiming to reduce potential leakage applied to OSBRA pipeline

    Energy Technology Data Exchange (ETDEWEB)

    Pires, L.F.G. [Pontificia Universidade Catolica do Rio de Janeiro (PUC-Rio), RJ (Brazil); Sousa, A.G.; Castro, N.C.; Spagnolo, R. [Petrobras Transporte S.A. (TRANSPETRO), Rio de Janeiro, RJ (Brazil)

    2009-07-01

    The discussion about motorizing block valves is a constant point being brought up when it is intended to control or reduce the amount of liquid leaking in the event of a pipe rupture. During the pipeline's project stage the installation of blocking valves along the pipeline must be taken into consideration to meet the operation and maintenance requirements as well as to reduce the potential amounts of volume being leaked. In existing pipelines, the main concern is the definition of which valves are candidates to be motorized. In both situations criteria should be established to define this choice. A math algorithm was developed to define the potential leakage due to gravity along the pipeline profile where the influence of a valve over another is verified, as well as the contribution of the check valves existing in the pipeline. The present work defines a parameter based on the extension protected by the valve and the reduction of the potential leakage. This parameter is then fed to a worksheet where the efficiency indicators are calculated to each valve eligible to be motorized. It also takes into consideration factors relative to the valve location, such as the environmental sensitivity, risk assessment, social diagnosis and device's proximity to contingency resources. Finally, after considering all the above aspects, it's possible to come up with a final classification, recommending specific valves to be prioritized on an eventual process of motorization adequacies. This methodology was applied, experimentally on a pipe segment of TRANSPETRO's Sao Paulo-Brasilia pipeline - OSBRA , where it proved to be an important technological and management tool. (author)

  5. Method of defining isolation parameters in 1000 Watt symmetric electricity network

    Directory of Open Access Journals (Sweden)

    Samat Amurgaliev

    2009-10-01

    Full Text Available The authors define parameters for isolation three-phase electric network to provide safety conditions for personnel working at open-operated coal deposits. The authors conclude the technique provides satisfactory accuracy of the parameters’ defining, as well as simplicity and safety of coal mining works with electric network having pressure up to 1000 Watt.

  6. A definability theorem for first order logic

    NARCIS (Netherlands)

    Butz, C.; Moerdijk, I.

    2001-01-01

    In this paper we will present a definability theorem for first order logic This theorem is very easy to state and its proof only uses elementary tools To explain the theorem let us first observe that if M is a model of a theory T in a language L then clearly any definable subset S M ie a subset S

  7. Defining Dynamic Graphics by a Graphical Language

    Institute of Scientific and Technical Information of China (English)

    毛其昌; 戴汝为

    1991-01-01

    A graphical language which can be used for defining dynamic picture and applying control actions to it is defined with an expanded attributed grammar.Based on this a system is built for developing the presentation of application data of user interface.This system provides user interface designers with a friendly and high efficient programming environment.

  8. 7 CFR 29.12 - Terms defined.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Terms defined. 29.12 Section 29.12 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing... INSPECTION Regulations Definitions § 29.12 Terms defined. As used in this subpart and in all...

  9. Quantifying Water Stress Using Total Water Volumes and GRACE

    Science.gov (United States)

    Richey, A. S.; Famiglietti, J. S.; Druffel-Rodriguez, R.

    2011-12-01

    Water will follow oil as the next critical resource leading to unrest and uprisings globally. To better manage this threat, an improved understanding of the distribution of water stress is required today. This study builds upon previous efforts to characterize water stress by improving both the quantification of human water use and the definition of water availability. Current statistics on human water use are often outdated or inaccurately reported nationally, especially for groundwater. This study improves these estimates by defining human water use in two ways. First, we use NASA's Gravity Recovery and Climate Experiment (GRACE) to isolate the anthropogenic signal in water storage anomalies, which we equate to water use. Second, we quantify an ideal water demand by using average water requirements for the domestic, industrial, and agricultural water use sectors. Water availability has traditionally been limited to "renewable" water, which ignores large, stored water sources that humans use. We compare water stress estimates derived using either renewable water or the total volume of water globally. We use the best-available data to quantify total aquifer and surface water volumes, as compared to groundwater recharge and surface water runoff from land-surface models. The work presented here should provide a more realistic image of water stress by explicitly quantifying groundwater, defining water availability as total water supply, and using GRACE to more accurately quantify water use.

  10. Human Work Interaction Design. Work Analysis and HCI

    DEFF Research Database (Denmark)

    Paasch, Kasper

    2013-01-01

    This book constitutes the thoroughly refereed post-conference proceedings of the Third IFIP WG 13.6 Working Conference on Human Work Interaction Design, HWID 2012, held in Copenhagen, Denmark, in December 2012. The 16 revised papers presented were carefully selected for inclusion in this volume...

  11. Volume-effect and radiotherapy [2]. Part 2: volume-effect and normal tissue; Effet volume en radiotherapie [2]. Deuxieme partie: volume et tolerance des tissus sains

    Energy Technology Data Exchange (ETDEWEB)

    Huchet, A.; Caudry, M.; Trouette, R.; Vendrely, V.; Causse, N.; Recaldini, L.; Maire, J.P. [Hopital Saint Andre, Service de Radiotherapie, 33 - Bordeaux (France); Belkacemi, Y. [Centre de Lutte Contre le Cancer Oscar-Lambret, Dept. de Radiotherapie, 59 - Lille (France); Atlan, D. [Hopital Europeen Georges Pompidou, Service de Radiotherapie, 75 - Paris (France)

    2003-10-01

    The first part of our work has focused on the relationship bet men tumor Volume and tumor control. Indeed, it is well known that the importance of irradiated volume could be a main parameter of radiation-induced complications. Numerous mathematical models have described the correlation between the irradiated volume and the risk of adverse effects. These models should predict the complication rate of each treatment planning. At the present time late effects have been the most studied. In this report we firstly propose a review of different mathematical models described for volume effect. Secondly, we will discuss whether these theoretical considerations can influence our view of radiation treatment planning optimization. (authors)

  12. The average free volume model for liquids

    CERN Document Server

    Yu, Yang

    2014-01-01

    In this work, the molar volume thermal expansion coefficient of 59 room temperature ionic liquids is compared with their van der Waals volume Vw. Regular correlation can be discerned between the two quantities. An average free volume model, that considers the particles as hard core with attractive force, is proposed to explain the correlation in this study. A combination between free volume and Lennard-Jones potential is applied to explain the physical phenomena of liquids. Some typical simple liquids (inorganic, organic, metallic and salt) are introduced to verify this hypothesis. Good agreement from the theory prediction and experimental data can be obtained.

  13. IPD-Work consortium

    DEFF Research Database (Denmark)

    Kivimäki, Mika; Singh-Manoux, Archana; Virtanen, Marianna

    2015-01-01

    to advance research on associations between work-related psychosocial risk factors and health; (ii) demonstrate as unfounded Choi et al's assertion that IPD-Work has underestimated associations between job strain and health endpoints; these include the dichotomous measurement of job strain, potential......Established in 2008 and comprising over 60 researchers, the IPD-Work (individual-participant data meta-analysis in working populations) consortium is a collaborative research project that uses pre-defined meta-analyses of individual-participant data from multiple cohort studies representing a range......-Work's findings have also generated disagreement as they challenge the importance of job strain as a major target for coronary heart disease (CHD) prevention, this is reflected in the critical discussion paper by Choi et al (1). In this invited reply to Choi et al, we aim to (i) describe how IPD-Work seeks...

  14. Interpretation of Spirometry: Selection of Predicted Values and Defining Abnormality.

    Science.gov (United States)

    Chhabra, S K

    2015-01-01

    Spirometry is the most frequently performed investigation to evaluate pulmonary function. It provides clinically useful information on the mechanical properties of the lung and the thoracic cage and aids in taking management-related decisions in a wide spectrum of diseases and disorders. Few measurements in medicine are so dependent on factors related to equipment, operator and the patient. Good spirometry requires quality assured measurements and a systematic approach to interpretation. Standard guidelines on the technical aspects of equipment and their calibration as well as the test procedure have been developed and revised from time-to-time. Strict compliance with standardisation guidelines ensures quality control. Interpretation of spirometry data is based only on two basic measurements--the forced vital capacity (FVC) and the forced expiratory volume in 1 second (FEV1) and their ratio, FEV1/FVC. A meaningful and clinically useful interpretation of the measured data requires a systematic approach and consideration of several important issues. Central to interpretation is the understanding of the development and application of prediction equations. Selection of prediction equations that are appropriate for the ethnic origin of the patient is vital to avoid erroneous interpretation. Defining abnormal values is a debatable but critical aspect of spirometry. A statistically valid definition of the lower limits of normal has been advocated as the better method over the more commonly used approach of defining abnormality as a fixed percentage of the predicted value. Spirometry rarely provides a specific diagnosis. Examination of the flow-volume curve and the measured data provides information to define patterns of ventilatory impairment. Spirometry must be interpreted in conjunction with clinical information including results of other investigations.

  15. Bilayer graphene quantum dot defined by topgates

    Energy Technology Data Exchange (ETDEWEB)

    Müller, André; Kaestner, Bernd; Hohls, Frank; Weimann, Thomas; Pierz, Klaus; Schumacher, Hans W., E-mail: hans.w.schumacher@ptb.de [Physikalisch-Technische Bundesanstalt, Bundesallee 100, 38116 Braunschweig (Germany)

    2014-06-21

    We investigate the application of nanoscale topgates on exfoliated bilayer graphene to define quantum dot devices. At temperatures below 500 mK, the conductance underneath the grounded gates is suppressed, which we attribute to nearest neighbour hopping and strain-induced piezoelectric fields. The gate-layout can thus be used to define resistive regions by tuning into the corresponding temperature range. We use this method to define a quantum dot structure in bilayer graphene showing Coulomb blockade oscillations consistent with the gate layout.

  16. Pulse volume discharges in high pressure gases

    Science.gov (United States)

    Yamshchikov, V. A.

    2015-11-01

    New approach for suppression of plasma inhomogeneities and instabilities in the volume self-sustained discharge is offered. The physical model is offered and conditions of obtaining extremely homogeneous self-sustained discharge are defined (with full suppression of plasma inhomogeneity and instability). Results of calculations agree with experiments.

  17. Work Coordination Engine

    Science.gov (United States)

    Zendejas, Silvino; Bui, Tung; Bui, Bach; Malhotra, Shantanu; Chen, Fannie; Kim, Rachel; Allen, Christopher; Luong, Ivy; Chang, George; Sadaqathulla, Syed

    2009-01-01

    The Work Coordination Engine (WCE) is a Java application integrated into the Service Management Database (SMDB), which coordinates the dispatching and monitoring of a work order system. WCE de-queues work orders from SMDB and orchestrates the dispatching of work to a registered set of software worker applications distributed over a set of local, or remote, heterogeneous computing systems. WCE monitors the execution of work orders once dispatched, and accepts the results of the work order by storing to the SMDB persistent store. The software leverages the use of a relational database, Java Messaging System (JMS), and Web Services using Simple Object Access Protocol (SOAP) technologies to implement an efficient work-order dispatching mechanism capable of coordinating the work of multiple computer servers on various platforms working concurrently on different, or similar, types of data or algorithmic processing. Existing (legacy) applications can be wrapped with a proxy object so that no changes to the application are needed to make them available for integration into the work order system as "workers." WCE automatically reschedules work orders that fail to be executed by one server to a different server if available. From initiation to completion, the system manages the execution state of work orders and workers via a well-defined set of events, states, and actions. It allows for configurable work-order execution timeouts by work-order type. This innovation eliminates a current processing bottleneck by providing a highly scalable, distributed work-order system used to quickly generate products needed by the Deep Space Network (DSN) to support space flight operations. WCE is driven by asynchronous messages delivered via JMS indicating the availability of new work or workers. It runs completely unattended in support of the lights-out operations concept in the DSN.

  18. Control volume based hydrocephalus research

    Science.gov (United States)

    Cohen, Benjamin; Voorhees, Abram; Wei, Timothy

    2008-11-01

    Hydrocephalus is a disease involving excess amounts of cerebral spinal fluid (CSF) in the brain. Recent research has shown correlations to pulsatility of blood flow through the brain. However, the problem to date has presented as too complex for much more than statistical analysis and understanding. This talk will highlight progress on developing a fundamental control volume approach to studying hydrocephalus. The specific goals are to select physiologically control volume(s), develop conservation equations along with the experimental capabilities to accurately quantify terms in those equations. To this end, an in vitro phantom is used as a simplified model of the human brain. The phantom's design consists of a rigid container filled with a compressible gel. The gel has a hollow spherical cavity representing a ventricle and a cylindrical passage representing the aquaducts. A computer controlled piston pump supplies pulsatile volume fluctuations into and out of the flow phantom. MRI is used to measure fluid velocity, and volume change as functions of time. Independent pressure measurements and flow rate measurements are used to calibrate the MRI data. These data are used as a framework for future work with live patients.

  19. Defining Human Failure Events for Petroleum Risk Analysis

    Energy Technology Data Exchange (ETDEWEB)

    Ronald L. Boring; Knut Øien

    2014-06-01

    In this paper, an identification and description of barriers and human failure events (HFEs) for human reliability analysis (HRA) is performed. The barriers, called target systems, are identified from risk significant accident scenarios represented as defined situations of hazard and accident (DSHAs). This report serves as the foundation for further work to develop petroleum HFEs compatible with the SPAR-H method and intended for reuse in future HRAs.

  20. Multiband Software Defined Radar for Soil Discontinuities Detection

    Directory of Open Access Journals (Sweden)

    S. Costanzo

    2013-01-01

    Full Text Available A multiband Software Defined Radar based on orthogonal frequency-division multiplexing technique is proposed in this work for an accurate soil discontinuities detection, taking into account also the dispersive behavior of media. A multilayer soil structure is assumed as a validation test to demonstrate the effectiveness of the proposed approach, by accurately retrieving the unknown thicknesses and permittivities of the soil layers.

  1. Ovarian volume throughout life

    DEFF Research Database (Denmark)

    Kelsey, Thomas W; Dodwell, Sarah K; Wilkinson, A Graham

    2013-01-01

    cancer. To date there is no normative model of ovarian volume throughout life. By searching the published literature for ovarian volume in healthy females, and using our own data from multiple sources (combined n=59,994) we have generated and robustly validated the first model of ovarian volume from...... to about 2.8 mL (95% CI 2.7-2.9 mL) at the menopause and smaller volumes thereafter. Our model allows us to generate normal values and ranges for ovarian volume throughout life. This is the first validated normative model of ovarian volume from conception to old age; it will be of use in the diagnosis...

  2. Clinical significance of CT-defined minimal ascites in patients with gastric cancer

    Institute of Scientific and Technical Information of China (English)

    Dong Kyung Chang; Ji Won Kim; Byung Kwan Kim; Kook Lae Lee; Chi Sung Song; Joon Koo Han; In Sung Song

    2005-01-01

    AIM: To study the clinical significance of minimal ascites,which was only defined by the CT and whose nature was not determined preoperatively, in the relationship with the peritoneal carcinomatosis.METHODS: The medical records and the dynamic CT films of 118 patients with gastric cancer were reviewed.Factors associated with peritoneal carcinomatosis were analyzed in 40 patients who had CT-defined ascites of which the nature was surgically confirmed.RESULTS: Only 12.5-25% of the CT-defined minimal ascites, whose volume was estimated to be less than 50 mL, were associated with peritoneal carcinomatosis.When the estimated CT-defined ascitic volume was 50 mL or more, peritoneal carcinomatosis was identified in 75-100%. When CT-defined lymph node enlargements were not found beyond the regional gastric area,perigastricinvasions were not suspected, and the size of tumor was less than 3 cm, peritoneal carcinomatosis seemed significantly less accompanied at the univariate analysis. However, except for the minimal volume of CTdefined ascites in comparison with the mild or more,other factors were not confirmed multivariately.CONCLUSION: In the patients with gastric cancer, CTdefined minimal ascites alone is rarely associated with peritoneal carcinomatosis, if it does not accompany other signs suggestive of malignant seeding. Therefore,consideration of active curative resection should not be hesitated, if CT-defined minimal ascites is the only delusive sign.

  3. Reconfigurable, Cognitive Software Defined Radio Project

    Data.gov (United States)

    National Aeronautics and Space Administration — Intelligent Automation Inc, (IAI) is currently developing a software defined radio (SDR) platform that can adaptively switch between different modes of operation for...

  4. Reconfigurable, Cognitive Software Defined Radio Project

    Data.gov (United States)

    National Aeronautics and Space Administration — IAI is actively developing Software Defined Radio platforms that can adaptively switch between different modes of operation by modifying both transmit waveforms and...

  5. Convolutional Goppa codes defined on fibrations

    CERN Document Server

    Curto, J I Iglesias; Martín, F J Plaza; Sotelo, G Serrano

    2010-01-01

    We define a new class of Convolutional Codes in terms of fibrations of algebraic varieties generalizaing our previous constructions of Convolutional Goppa Codes. Using this general construction we can give several examples of Maximum Distance Separable (MDS) Convolutional Codes.

  6. Radiation Tolerant Software Defined Video Processor Project

    Data.gov (United States)

    National Aeronautics and Space Administration — MaXentric's is proposing a radiation tolerant Software Define Video Processor, codenamed SDVP, for the problem of advanced motion imaging in the space environment....

  7. Towards a Southern African English Defining Vocabulary

    African Journals Online (AJOL)

    user

    In my experience, defining vocabularies compiled for English dictionaries for a British or .... Oxford 3000, which contains 3 540 entries, and is available on the Internet. ... One thing that became apparent was a lack of consistency within lexical.

  8. Software Defined Multiband EVA Radio Project

    Data.gov (United States)

    National Aeronautics and Space Administration — The objective of this research is to propose a reliable, lightweight, programmable, multi-band, multi-mode, miniaturized frequency-agile EVA software defined radio...

  9. Software Defined Multiband EVA Radio Project

    Data.gov (United States)

    National Aeronautics and Space Administration — The objective of Phase 2 is to build a reliable, lightweight, programmable, multi-mode, miniaturized EVA Software Defined Radio (SDR) that supports data telemetry,...

  10. Optimum Criteria for Developing Defined Structures

    Directory of Open Access Journals (Sweden)

    Ion IVAN

    2008-01-01

    Full Text Available Basic aspects concerning distributed applications are presented: definition, particularities and importance. For distributed applications linear, arborescent, graph structures are defined with different versions and aggregation methods. Distributed applications have associated structures which through their characteristics influence the costs of the stages in the development cycle and the exploitation costs transferred to each user. The complexity of the defined structures is analyzed. The minimum and maximum criteria are enumerated for optimizing distributed application structures.

  11. Mobility Work

    DEFF Research Database (Denmark)

    Bardram, Jakob Eyvind; Bossen, Claus

    2005-01-01

    by constructing Standard Operation Procedures (SOPs), actors minimise mobility work by constructing Standard Operation Configurations (SOCs). We apply the concept of mobility work to the ethnography of hospital work, and argue that mobility arises because of the need to get access to people, places, knowledge and....../or resources. To accomplish their work, actors have to make the right configuration of these four aspects emerge....

  12. Developmental Work

    DEFF Research Database (Denmark)

    Møller, Niels; Hvid, Helge; Kristensen, Tage Søndergaard

    2003-01-01

    Human Deveoplment and Working Life - Work for Welfare explores whether the development of human resources at company level can improve individuals' quality of life, companies' possibilities of development, and welfare and democracy in society. Chapter two discuss the concept "developmental work...

  13. Developmental Work

    DEFF Research Database (Denmark)

    Møller, Niels; Hvid, Helge; Kristensen, Tage Søndergaard;

    2003-01-01

    Human Deveoplment and Working Life - Work for Welfare explores whether the development of human resources at company level can improve individuals' quality of life, companies' possibilities of development, and welfare and democracy in society. Chapter two discuss the concept "developmental work...

  14. Mi Primer Libro de Maquinas Simples: Trabajo y Fuerza. Escuela Intermedia Grados 7, 8 y 9 (My First Book of Simple Machines: Work and Force. Intermediate School Grades 7, 8, and 9).

    Science.gov (United States)

    Alvarado, Patricio R.; Montalvo, Luis

    This is the first book in a five-book physical science series on simple machines. The books are designed for Spanish-speaking junior high school students. This volume defines force and work by suggesting experiments and posing questions concerning drawings in the book which illustrate scientific principles. Answers to the questions are provided;…

  15. Mean nuclear volume

    DEFF Research Database (Denmark)

    Mogensen, O.; Sørensen, Flemming Brandt; Bichel, P.

    1999-01-01

    We evaluated the following nine parameters with respect to their prognostic value in females with endometrial cancer: four stereologic parameters [mean nuclear volume (MNV), nuclear volume fraction, nuclear index and mitotic index], the immunohistochemical expression of cancer antigen (CA125...

  16. CTC Sentinel. Volume 2, Issue 4, April 2009. Defining the Punjabi Taliban Network

    Science.gov (United States)

    2009-04-01

    publication, Sada al-Malahim (The Echo of Battles), is frequently timed for release shortly before or after a new operation, and provides...well before there were even rumors of Saudi influence in al-Qa`ida in Yemen. In the latest issue of Sada al-Malahim, Nayf Muhammad al-Qahtani, a...latest issue of Sada al-Malahim was released on March 21, 2009 and is available on various jihadist web forums. Indeed, the statement of

  17. Federal register, Volume 60, No. 234, Wednesday, December 6, 1995 proposed rules. Part 2. 40 CFR part 122, et al. National pollutant discharge elimination system permit application requirements for publicly owned treatment works and other treatment works treating domestic sewage; proposed rule

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-12-06

    The Environmental Protection Agency proposes to amend permit application requirements and application forms for publicly owned treatment works (POTWs) and other treatment works treating domestic sewage (TWTDS). TWTDS include facilities that generate sewage sludge, provide commercial treatment of sewage sludge, manufacture a product derived from sewage sludge, or provide disposal of sewage sludge.

  18. Exposure Render: An Interactive Photo-Realistic Volume Rendering Framework

    NARCIS (Netherlands)

    Kroes, T.; Post, F.H.; Botha, C.P.

    2012-01-01

    The field of volume visualization has undergone rapid development during the past years, both due to advances in suitable computing hardware and due to the increasing availability of large volume datasets. Recent work has focused on increasing the visual realism in Direct Volume Rendering (DVR) by i

  19. BOX: One Minute Volume 3

    OpenAIRE

    Butler, Rose

    2009-01-01

    BOX is a digital short originally developed in 2004 documented on a 1920’s box camera. This early moving image work formed the basis of a practice which interrogates our experience of moving image through the remediation of analogue technology with new media. In 2009 it was included in One Minute Volume 3; a programme of artists moving image curated by Kerry Baldry including work by: Tony Hill, Tina Keane, Katherine Meynell, Kayla Parker and Stuart Moore, Dave Griffiths, Marty St Jam...

  20. Working satisfaction and views towards team work of mobile special education teachers

    OpenAIRE

    Veber, Saša

    2016-01-01

    In this diploma thesis I researched the working satisfaction and views of mobile special education teachers towards team work. In the introductory part I defined what working satisfaction is, I described the work of mobile special education teachers, I defined team work at school and described the role of mobile special education teachers' views. In the research I established how satisfied mobile special education teachers are at their work, what are their positions and views towards team wor...

  1. Software-Defined Cellular Mobile Network Solutions

    Institute of Scientific and Technical Information of China (English)

    Jiandong Li; Peng Liu; Hongyan Li

    2014-01-01

    The emergency relating to software-defined networking (SDN), especially in terms of the prototype associated with OpenFlow, pro-vides new possibilities for innovating on network design. Researchers have started to extend SDN to cellular networks. Such new programmable architecture is beneficial to the evolution of mobile networks and allows operators to provide better services. The typical cellular network comprises radio access network (RAN) and core network (CN); hence, the technique roadmap diverges in two ways. In this paper, we investigate SoftRAN, the latest SDN solution for RAN, and SoftCell and MobileFlow, the latest solu-tions for CN. We also define a series of control functions for CROWD. Unlike in the other literature, we emphasize only software-defined cellular network solutions and specifications in order to provide possible research directions.

  2. BIOMARKERS TO DEFINE OPTIMAL PROTEIN REQUIREMENT

    OpenAIRE

    Di Girolamo, Filippo Giorgio

    2015-01-01

    Dietary proteins are the source of the amino acids required by the body for tissue growth and maintenance. The Population Reference Intake (PRI) for proteins, as defined by the European Food Safety Authority (EFSA) for healthy adults, including the elderly, is 0.83 g/kg body weight/day. This amount is defined on the net balance of body protein (or “nitrogen balance”, given by the difference between dietary nitrogen intake and losses) equivalent to 0.66 g/kg/day plus a safety factor for interp...

  3. GNU Based Security in Software Defined Radio

    Directory of Open Access Journals (Sweden)

    H. B. Bhadka

    2012-11-01

    Full Text Available Various new technologies are explored for radio communication toward the 21st century. Among them the technology of "software defined radio" attracts large attention. Software Defined Radio (SDR technology implements some of the functional modules of a radio system in software enabling highly flexible handsets. SDR devices may be reconfigured dynamically via the download of new software modules. Malicious or malfunctioning downloaded software present serious security risks to SDR devices and networks in which they operate. Together with the use of software downloading, future terminals will become a platform to support the deployment of yet unspecified services and applications.

  4. Medical abortion. defining success and categorizing failures

    DEFF Research Database (Denmark)

    Rørbye, Christina; Nørgaard, Mogens; Vestermark, Vibeke;

    2003-01-01

    Medical abortion was performed in 461 consecutive women with gestational age LT /= 63 days using a regimen of mifepristone 600 mg followed 2 days later by gemeprost 1 mg vaginally. Success, defined as no surgical intervention, declined from 98.7% after 2 weeks to 94.6% after 15 weeks. The differe......Medical abortion was performed in 461 consecutive women with gestational age LT /= 63 days using a regimen of mifepristone 600 mg followed 2 days later by gemeprost 1 mg vaginally. Success, defined as no surgical intervention, declined from 98.7% after 2 weeks to 94.6% after 15 weeks...

  5. What Defines a Separate Hydrothermal System

    Energy Technology Data Exchange (ETDEWEB)

    Lawless, J.V.; Bogie, I.; Bignall, G.

    1995-01-01

    Separate hydrothermal systems can be defined in a variety of ways. Criteria which have been applied include separation of heat source, upflow, economic resource and geophysical anomaly. Alternatively, connections have been defined by the effects of withdrawal of economically useful fluid and subsidence, effects of reinjection, changes in thermal features, or by a hydrological connection of groundwaters. It is proposed here that: ''A separate hydrothermal system is one that is fed by a separate convective upflow of fluid, at a depth above the brittle-ductile transition for the host rocks, while acknowledging that separate hydrothermal systems can be hydrologically interconnected at shallower levels''.

  6. A Rotational Crofton Formula for Flagged Intrinsic Volumes of Sets of Positive Reach

    DEFF Research Database (Denmark)

    Auneau, Jeremy Michel

    A rotational Crofton formula is derived relating the flagged intrinsic volumes of a compact set of positive reach with the flagged intrinsic volumes measured on sections passing through a fixed point. In particular cases, the flagged intrinsic volumes defined in the present paper are identical...... to the classical intrinsic volumes. The tight connection between our main result and other recent rotational integral formulae involving intrinsic volumes is pointed out....

  7. Mass anomalous dimension of Adjoint QCD at large N from twisted volume reduction

    CERN Document Server

    Pérez, Margarita García; Keegan, Liam; Okawa, Masanori

    2015-01-01

    In this work we consider the $SU(N)$ gauge theory with two Dirac fermions in the adjoint representation, in the limit of large $N$. In this limit the infinite-volume physics of this model can be studied by means of the corresponding twisted reduced model defined on a single site lattice. Making use of this strategy we study the reduced model for various values of $N$ up to 289. By analyzing the eigenvalue distribution of the adjoint Dirac operator we test the conformality of the theory and extract the corresponding mass anomalous dimension.

  8. Audiences : Defining and Researching Screen Entertainment Reception

    OpenAIRE

    2012-01-01

    This timely volume engages with one of the most important shifts in recent film studies: the turn away from text-based analysis towards the viewer. Historically, this marks a return to early interest in the effect of film on the audience by psychoanalysts and psychologists, which was overtaken by concern with the 'effects' of film, linked to calls for censorship and moral panics rather than to understanding the mental and behavioral world of the spectator. Early cinema history has revealed th...

  9. Volume of intersection of two cones

    CERN Document Server

    Balogun, F A; Cesareo, R

    2000-01-01

    Radiation measurements utilising collimated source and detector systems invariably result in a target volume described by the overlap of their fields of view. When these collimators are cylindrical, this is derived from the volume of intersection of two cones. In general, analysis of this volume does not lend itself to a direct analytical process. Here, numerical methods of estimating the common volume of two intersecting right cones are presented. These include methods which employ, (a) a sequential scanning of an elemental volume with a predetermined size across a defined space containing the volume of interest and (b) a Monte Carlo technique. The accuracy obtainable and the execution time in the first type of algorithm depend on the size of the elemental volume (bin-size). On the other hand, these two parameters are independent of the bin-size but dependent on the number of histories sampled, for the Monte Carlo technique. At 0 deg. angle of inclination, where an analytical estimation is easily obtained, t...

  10. Paper works

    DEFF Research Database (Denmark)

    Rasmussen, Mattias Borg

    2017-01-01

    of their land and natural resources, but also of labor and territorial sovereignty. This case shows how an Andean campesino community counters such movements by a wide repertoire of legal and social actions that works simultaneously in legal and extra-legal domains. Paper works mediate claims to territorial...

  11. Works Councils

    DEFF Research Database (Denmark)

    Knudsen, Herman Lyhne; Markey, Ray

    2002-01-01

    The article outlines the operation of works councils in Europe and in the context of disscussing their viability in Austalia.......The article outlines the operation of works councils in Europe and in the context of disscussing their viability in Austalia....

  12. Sedentary work

    DEFF Research Database (Denmark)

    Eriksen, Dorte; Rosthøj, Susanne; Burr, Hermann

    2015-01-01

    OBJECTIVE: The aim of this study is to investigate the association between five-year changes in occupational sitting and body mass index (BMI) in working adults. METHODS: We analyzed data from The Danish Work Environment Cohort Study (2005 and 2010, n=3.482). Data on occupational sitting, weight...

  13. Bruxism defined and graded: an international consensus

    NARCIS (Netherlands)

    Lobbezoo, F.; Ahlberg, J.; Glaros, A.G.; Kato, T.; Koyano, K.; Lavigne, G.J.; de Leeuw, R.; Manfredini, D.; Svensson, P.; Winocur, E.

    2013-01-01

    To date, there is no consensus about the definition and diagnostic grading of bruxism. A written consensus discussion was held among an international group of bruxism experts as to formulate a definition of bruxism and to suggest a grading system for its operationalisation. The expert group defined

  14. Defining, constructing and assessing learning outcomes.

    Science.gov (United States)

    Taylor, R M

    2009-08-01

    Learning outcomes define the veterinary curriculum and inform students about what they must be able to demonstrate to succeed. Stakeholder consultation during their development ensures that programme learning outcomes equip graduates to contribute to the veterinary profession. Effective learning outcomes form a hierarchy linking the programme, its courses and tasks. Clear outcomes direct students towards higher quality learning by indicating the achievements intended, but leave scope for emergent learning outcomes. Defined technical competencies fit within this overarching framework, complementing higher order learning. Mapping is used to align learning outcomes horizontally and vertically so students are systematically guided towards entry-level competence and professional independence. Constructively aligned learning and assessment tasks ensure learners spend the focused time required to sequentially develop programme outcomes. Assessment by staff, peers and other stakeholders certifies achievement of intended outcomes. Effective assessment also empowers students to define and achieve their own learning outcomes, so they develop the habits of autonomous life-long learning. Evaluation of the quality and consistency of achieved outcomes informs ongoing programme improvement. If we are going to achieve the objectives of this set of papers, i.e. to improve public health education globally (Rev. sci. tech. Off. int. Epiz. 28 [2] 2009), then it is essential that they be well defined in the learning outcomes statement of all veterinary schools.

  15. Restandardisation defined as democratising language planning1

    African Journals Online (AJOL)

    aims to define restandardisation as democratising language planning, i.e. a .... disintegration of the Soviet Union of Yugoslavia, the opening of borders in Europe, and the ..... descriptive framework for standardisation as a language planning process. .... belonging to the same language group in order to form one common ...

  16. 7 CFR 51.2 - Terms defined.

    Science.gov (United States)

    2010-01-01

    ... Definitions § 51.2 Terms defined. Words in the regulations in this part in the singular form shall be deemed.... “Federal-State Inspection Agency” means any State agency, business association or trade organization... plant. “Packing plant” means the premises, buildings, structures, and equipment including but...

  17. Defining benzodiazepine dependence: The confusion persists

    NARCIS (Netherlands)

    Linsen, S.M.; Zitman, F.G.; Breteler, M.H.M.

    1995-01-01

    Little consensus exists on the risk of benzodiazepine (BZD) dependence. We investigated how often BZD dependence and related concepts have been defined in the literature on BZD effects in humans. In addition, the definitions of BZD dependence were compared in order to assess the similarity of conten

  18. 47 CFR 54.401 - Lifeline defined.

    Science.gov (United States)

    2010-10-01

    ... Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER SERVICES (CONTINUED) UNIVERSAL SERVICE Universal Service Support for Low-Income Consumers § 54.401 Lifeline defined. (a) As used in this... assistance. Eligible telecommunications carriers not subject to state commission jurisdiction also shall...

  19. THEORETICAL APPROACHES DEFINE SENSE OF INVESTMENT PROJECT

    OpenAIRE

    Yu. A. Burduzha

    2010-01-01

    The essence of terms “project”, “investment project” is defined in the article, as well as the difference between definitions of terms “project”, “plan” and “program” is determined. The main approaches to the treatment of definition of term “investment project” are considered.

  20. Precise Interval Timer for Software Defined Radio

    Science.gov (United States)

    Pozhidaev, Aleksey (Inventor)

    2014-01-01

    A precise digital fractional interval timer for software defined radios which vary their waveform on a packet-by-packet basis. The timer allows for variable length in the preamble of the RF packet and allows to adjust boundaries of the TDMA (Time Division Multiple Access) Slots of the receiver of an SDR based on the reception of the RF packet of interest.

  1. Externally definable sets and dependent pairs

    CERN Document Server

    Chernikov, Artem

    2010-01-01

    We prove that externally definable sets in first order NIP theories have honest definitions, giving a new proof of Shelah's expansion theorem. Also we discuss a weak notion of stable embeddedness true in this context. Those results are then used to prove a general theorem on dependent pairs, which in particular answers a question of Baldwin and Benedikt on naming an indiscernible sequence.

  2. Defining Parental Involvement: Perception of School Administrators

    Science.gov (United States)

    Young, Clara Y.; Austin, Sheila M.; Growe, Roslin

    2013-01-01

    There remains a plaguing question of how to get parents involved with their child's education. Many parents and educators have different perceptions of what parental involvement means. Miscommunication between the two groups often exists because of how parental involvement is conceptualized. While educators define parental involvement as…

  3. Defining enthesitis in spondyloarthritis by ultrasound

    DEFF Research Database (Denmark)

    Terslev, Lene; Naredo, E; Iagnocco, A

    2014-01-01

    Objective: To standardize ultrasound (US) in enthesitis. Methods: An Initial Delphi exercise was undertaken to define US detected enthesitis and its core components. These definitions were subsequently tested on static images taken from Spondyloarthritis (SpA) patients in order to evaluate...

  4. 16 CFR 303.1 - Terms defined.

    Science.gov (United States)

    2010-01-01

    ... that solicit ultimate consumers to purchase such textile products by mail, telephone, electronic mail... REGULATIONS UNDER THE TEXTILE FIBER PRODUCTS IDENTIFICATION ACT § 303.1 Terms defined. As used in this part, unless the context otherwise specifically requires: (a) The term Act means the Textile Fiber...

  5. Defining Grammatical Difficulty: A Student Teacher Perspective

    Science.gov (United States)

    Graus, Johan; Coppen, Peter-Arno

    2015-01-01

    Numerous second language acquisition (SLA) researchers have tried to define grammatical difficulty in second and foreign language acquisition--often as part of an attempt to relate the efficacy of different types of instruction to the degree of difficulty of grammatical structures. The resulting proliferation of definitions and the lack of a…

  6. 16 CFR 502.2 - Terms defined.

    Science.gov (United States)

    2010-01-01

    ... and customary and regular when used with the term price means the price at which a consumer commodity..., package, label, person, commerce, principal display panel, and random package have the same meaning as those terms are defined under part 500 of this chapter. (b) The term packager and labeler means any...

  7. Defining collaborative business rules management solutions

    NARCIS (Netherlands)

    dr. Martijn Zoet; Johan Versendaal

    2014-01-01

    From the publishers' website: The goal of this research is to define a method for configuring a collaborative business rules management solution from a value proposition perspective. In an earlier published study (Business rules management solutions: added value by means of business

  8. Defining and Operationalising L2 Complexity

    Science.gov (United States)

    Bulte, Bram; Housen, Alex

    2012-01-01

    This chapter takes a critical look at complexity in L2 research. We demonstrate several problems in the L2 literature in terms of how complexity has been defined and operationalised as a construct. In the first part of the chapter we try to unravel its highly complex, multidimensional nature by presenting a taxonomic model that identifies major…

  9. THEORETICAL APPROACHES DEFINE SENSE OF INVESTMENT PROJECT

    Directory of Open Access Journals (Sweden)

    Yu. A. Burduzha

    2010-11-01

    Full Text Available The essence of terms “project”, “investment project” is defined in the article, as well as the difference between definitions of terms “project”, “plan” and “program” is determined. The main approaches to the treatment of definition of term “investment project” are considered.

  10. Selected Works of Oded Schramm

    CERN Document Server

    Benjamini, Itai

    2011-01-01

    This volume is dedicated to the memory of the late Oded Schramm (1961-2008), distinguished statistician. Throughout his life, Oded made profound and beautiful contributions to mathematics that will have a lasting influence. In these two volumes, Editors Itai Benjamini and Olle Haggstrom have collected some of his papers, supplemented with three survey papers by Steffen Rohde, Haggstrom and Cristophe Garban that further elucidate his work. The papers within are a representative collection that shows the breadth, depth, enthusiasm and clarity of his work, with sections on Geometry, Noise Sensiti

  11. Work Temperament Inventory and Manual.

    Science.gov (United States)

    Bolton, Brian; Brookings, Jeffrey

    This manual is a guide to the Work Temperament Inventory (WTI), a self-report measure of 12 work temperaments that were originally identified and defined by the U.S. Department of Labor. The WTI consists of 134 items requiring a simple "like" or "dislike" response and a reading level of seventh grade. It can be completed in 15…

  12. Safety at Work : Research Methodology

    NARCIS (Netherlands)

    Beurden, van K. (Karin); Boer, de J. (Johannes); Brinks, G. (Ger); Goering-Zaburnenko, T. (Tatiana); Houten, van Y. (Ynze); Teeuw, W. (Wouter)

    2012-01-01

    In this document, we provide the methodological background for the Safety atWork project. This document combines several project deliverables as defined inthe overall project plan: validation techniques and methods (D5.1.1), performanceindicators for safety at work (D5.1.2), personal protection equi

  13. Effects of defining realistic compositions of the ocular melanoma on proton therapy.

    Science.gov (United States)

    Keshazare, Sh; Masoudi, S F; S Rasouli, F

    2014-12-01

    Recent studies in eye plaque brachytherapy have shown a considerable difference between the dosimetric results using water phantom and a model of human eye containing realistic materials. In spite of this fact, there is a lack of simulation studies based on such a model in proton therapy literatures. In the presented work, the effect of utilizing an eye model with ocular media on proton therapy is investigated using the MCNPX Monte Carlo Code. Two different eye models are proposed to study the effect of defining realistic materials on dose deposition due to utilizing pencil beam scanning (PBS) method for proton therapy of ocular melanoma. The first model is filled with water, and the second one contains the realistic materials of tumor and vitreous. Spread out Bragg peaks (SOBP) are created to cover a typical tumor volume. Moreover, isodose curves are figured in order to evaluate planar variations of absorbed dose in two models. The results show that the maximum delivered dose in ocular media is approximately 12-32% more than in water phantom. Also it is found that using the optimized weighted beams in water phantom leads to disturbance of uniformity of SOBP in ocular media. Similar to the results reported in eye brachytherapy published papers, considering the ocular media in simulation studies leads to a more realistic assessment of sufficiency of the designed proton beam in tissue. This effect is of special importance in creating SOBP, as well as in delivered dose in the tumor boundaries in proton pencil beam scanning method.

  14. Defining Medical Levels of Care for Exploration Missions

    Science.gov (United States)

    Hailey, M.; Reyes, D.; Urbina, M.; Rubin, D.; Antonsen, E.

    2017-01-01

    NASA medical care standards establish requirements for providing health and medical programs for crewmembers during all phases of a mission. These requirements are intended to prevent or mitigate negative health consequences of long-duration spaceflight, thereby optimizing crew health and performance over the course of the mission. Current standards are documented in the two volumes of the NASA-STD-3001 Space Flight Human-System Standard document, established by the Office of the Chief Health and Medical Officer. Its purpose is to provide uniform technical standards for the design, selection, and application of medical hardware, software, processes, procedures, practices, and methods for human-rated systems. NASA-STD-3001 Vol. 1 identifies five levels of care for human spaceflight. These levels of care are accompanied by several components that illustrate the type of medical care expected for each. The Exploration Medical Capability (ExMC) of the Human Research Program has expanded the context of these provided levels of care and components. This supplemental information includes definitions for each component of care and example actions that describe the type of capabilities that coincide with the definition. This interpretation is necessary in order to fully and systematically define the capabilities required for each level of care in order to define the medical requirements and plan for infrastructure needed for medical systems of future exploration missions, such as one to Mars.

  15. Volumetric flame synthesis of well-defined molybdenum oxide nanocrystals.

    Science.gov (United States)

    Merchan-Merchan, Wilson; Saveliev, Alexei V; Desai, Milind

    2009-11-25

    Well-defined faceted inorganic Mo oxide nanocrystals are synthesized in the gas phase using a solid-fed-precursor flame synthesis method. The solid crystals have rectangular cross-section with characteristic size of 10-20 nm and with lengths ranging from 50 nm to a few hundred nanometres. A 1 mm diameter high purity Mo probe introduced in the oxygen-rich part of the flame serves as the material source. A combination of the strong temperature gradient and varying chemical species concentrations within the flame volume provides the ideal conditions for the rapid and direct formation of these unique nanocrystals. Oxidation and evaporation of MoO3 in the oxygen-rich zone are followed by reduction to MoO2 in the lower temperature, more fuel-rich zone. The MoO3 vapours formed are pushed in the direction of the gas flow and transformed into mature well-defined convex polyhedron nanocrystals bounded with six faces resembling rectangular parallelepipeds.

  16. Volumetric flame synthesis of well-defined molybdenum oxide nanocrystals

    Energy Technology Data Exchange (ETDEWEB)

    Merchan-Merchan, Wilson; Desai, Milind [School of Aerospace and Mechanical Engineering, University of Oklahoma, Norman, OK 73019 (United States); Saveliev, Alexei V, E-mail: wmerchan-merchan@ou.ed [Department of Mechanical and Aerospace Engineering, North Carolina State University, Raleigh, NC 27695 (United States)

    2009-11-25

    Well-defined faceted inorganic Mo oxide nanocrystals are synthesized in the gas phase using a solid-fed-precursor flame synthesis method. The solid crystals have rectangular cross-section with characteristic size of 10-20 nm and with lengths ranging from 50 nm to a few hundred nanometres. A 1 mm diameter high purity Mo probe introduced in the oxygen-rich part of the flame serves as the material source. A combination of the strong temperature gradient and varying chemical species concentrations within the flame volume provides the ideal conditions for the rapid and direct formation of these unique nanocrystals. Oxidation and evaporation of MoO{sub 3} in the oxygen-rich zone are followed by reduction to MoO{sub 2} in the lower temperature, more fuel-rich zone. The MoO{sub 3} vapours formed are pushed in the direction of the gas flow and transformed into mature well-defined convex polyhedron nanocrystals bounded with six faces resembling rectangular parallelepipeds.

  17. Aspects of quantum work.

    Science.gov (United States)

    Talkner, Peter; Hänggi, Peter

    2016-02-01

    Various approaches of defining and determining work performed on a quantum system are compared. Any operational definition of work, however, must allow for two facts: first, that work characterizes a process rather than an instantaneous state of a system and, second, that quantum systems are sensitive to the interactions with a measurement apparatus. We compare different measurement scenarios on the basis of the resulting postmeasurement states and the according probabilities for finding a particular work value. In particular, we analyze a recently proposed work meter for the case of a Gaussian pointer state and compare it with the results obtained by two projective and, alternatively, two Gaussian measurements. In the limit of a strong effective measurement strength the work distribution of projective two energy measurements can be recovered. In the opposite limit the average of work becomes independent of any measurement. Yet the fluctuations about this value diverge. The performance of the work meter is illustrated by the example of a spin in a suddenly changing magnetic field.

  18. Implications of flexible work systems for work studies.

    Science.gov (United States)

    Kogi, K

    1997-12-01

    The relationship between changing work systems and work study methods is discussed by focusing on a recent trend toward more flexible work systems in different countries. These systems are commonly characterized by (a) uncoupling of working hours from business hours, (b) combining different atypical work forms and (c) individualized work patterns. Increased flexibility in working patterns is demanded because business hours may be covered by different workers and because special arrangements become necessary for unpopular shifts or linking separate jobs. Changes in work systems seem more successful when they are associated with (a) multiskilled work, (b) independent task implementation, (c) networked communication, (d) balanced or adjusted workload, and (e) accommodation of workers' preferences. Special attention is drawn to safety and health concerns and work-life effects. Many intervention studies done for work improvement are paying attention to multifaceted work aspects, locally available options, and participation by people. All these elements are important because prepackaged solutions do not exist. The following three views seem especially useful for action-oriented work studies: 1) Look at multiple aspects of the work, including work content and atypical work forms; 2) Know worker preferences and available options; and 3) Take into account work elements that may not be well defined, but important from local points of view. It is envisioned that these studies can provide support for a well-informed participatory process of work system changes in each local context.

  19. Work Stress

    OpenAIRE

    Roeters, Anne

    2014-01-01

    Most of us agree that stress is a growing problem within organizations. We hear about the postal workers who had killed fellow employees and supervisors, and then hear that a major cause of tension is at work. Friends tell us that they are stressed due to increased workload and he has to work overtime because the company is restructured. We read the polls that employees complain about the stress in trying to balance family life with the work. Stress is a dynamic condition in which an individu...

  20. Does "Social Work Abstracts" Work?

    Science.gov (United States)

    Holden, Gary; Barker, Kathleen; Covert-Vail, Lucinda; Rosenberg, Gary; Cohen, Stephanie A.

    2008-01-01

    Objective: The current study seeks to provide estimates of the adequacy of journal coverage in the Social Work Abstracts (SWA) database. Method: A total of 23 journals listed in the Journal Citation Reports social work category during the 1997 to 2005 period were selected for study. Issue-level coverage estimates were obtained for SWA and…

  1. Does "Social Work Abstracts" Work?

    Science.gov (United States)

    Holden, Gary; Barker, Kathleen; Covert-Vail, Lucinda; Rosenberg, Gary; Cohen, Stephanie A.

    2008-01-01

    Objective: The current study seeks to provide estimates of the adequacy of journal coverage in the Social Work Abstracts (SWA) database. Method: A total of 23 journals listed in the Journal Citation Reports social work category during the 1997 to 2005 period were selected for study. Issue-level coverage estimates were obtained for SWA and…

  2. Areas and volumes for null cones

    CERN Document Server

    Grant, James D E

    2010-01-01

    Motivated by recent work of Choquet-Bruhat, Chrusciel, and Martin-Garcia, we prove monotonicity properties and comparison results for the area of slices of the null cone of a point in a Lorentzian manifold. We also prove volume comparison results for subsets of the null cone analogous to the Bishop-Gromov relative volume monotonicity theorem and Guenther's volume comparison theorem. We briefly discuss how these estimates may be used to control the null second fundamental form of slices of the null cone in Ricci-flat Lorentzian four-manifolds with null curvature bounded above.

  3. Sandia Software Guidelines, Volume 2. Documentation

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-09-01

    This volume is one in a series of Sandia Software Guidelines intended for use in producing quality software within Sandia National Laboratories. In consonance with the IEEE Standards for software documentation, this volume provides guidance in the selection of an adequate document set for a software project and example formats for many types of software documentation. A tutorial on life cycle documentation is also provided. Extended document thematic outlines and working examples of software documents are available on electronic media as an extension of this volume.

  4. CITA works

    DEFF Research Database (Denmark)

    Ramsgaard Thomsen, Mette; Tamke, Martin; Ayres, Phil;

    2015-01-01

    CITA works documents over 40 projects, events and research collaborations conducted between 2005 and 2014 by the Centre for Information Technology and Architecture (CITA). Through individual project descriptions accompanied by photographic documentation and design drawings, CITA works provides...... readers with insights into our design-led practice-based architectural research which queries how computation challenges the way we think, design and build architecture. With essays by Professor Mette Ramsgaard Thomsen (Head of CITA), and Dr. Jane Burry (Head of the Spatial Information Architecture...... Laboratory, RMIT) the work is contextualised within the field of digital architectural design practice. These essays also identify the emerging questions and maturing methods that continue to inform CITA’s research within this territory. CITA works marks the first 10 years of our research effort...

  5. PROMIS series. Volume 8: Midlatitude ground magnetograms

    Science.gov (United States)

    Fairfield, D. H.; Russell, C. T.

    1990-01-01

    This is the eighth in a series of volumes pertaining to the Polar Region Outer Magnetosphere International Study (PROMIS). This volume contains 24 hour stack plots of 1-minute average, H and D component, ground magnetograms for the period March 10 through June 16, 1986. Nine midlatitude ground stations were selected from the UCLA magnetogram data base that was constructed from all available digitized magnetogram stations. The primary purpose of this publication is to allow users to define universal times and onset longitudes of magnetospheric substorms.

  6. FINANCIAL ACCOUNTING QUALITY AND ITS DEFINING CHARACTERISTICS

    Directory of Open Access Journals (Sweden)

    Andra M. ACHIM

    2014-11-01

    Full Text Available The importance ofhigh-quality financial statements is highlighted by the main standard-setting institutions activating in the field of accounting and reporting. These have issued Conceptual Frameworks which state and describe the qualitative characteristics of accounting information. In this qualitative study, the research methodology consists of reviewing the literature related to the definition of accounting quality and striving for understanding how it can be explained. The main objective of the study is to identify the characteristics information should possess in order to be of high quality. These characteristics also contribute to the way of defining financial accounting quality. The main conclusions that arise from this research are represented by the facts that indeed financial accounting quality cannot be uniquely defined and that financial information is of good quality when it enhances the characteristics incorporated in the conceptual frameworks issued by both International Accounting Standards Board and Financial Accounting Standards Board.

  7. Defining Tiger Parenting in Chinese Americans.

    Science.gov (United States)

    Kim, Su Yeong

    2013-09-01

    "Tiger" parenting, as described by Amy Chua [2011], has instigated scholarly discourse on this phenomenon and its possible effects on families. Our eight-year longitudinal study, published in the Asian American Journal of Psychology [Kim, Wang, Orozco-Lapray, Shen, & Murtuza, 2013b], demonstrates that tiger parenting is not a common parenting profile in a sample of 444 Chinese American families. Tiger parenting also does not relate to superior academic performance in children. In fact, the best developmental outcomes were found among children of supportive parents. We examine the complexities around defining tiger parenting by reviewing classical literature on parenting styles and scholarship on Asian American parenting, along with Amy Chua's own description of her parenting method, to develop, define, and categorize variability in parenting in a sample of Chinese American families. We also provide evidence that supportive parenting is important for the optimal development of Chinese American adolescents.

  8. Defining life or bringing biology to life.

    Science.gov (United States)

    Ruiz-Mirazo, Kepa; Peretó, Juli; Moreno, Alvaro

    2010-04-01

    In the present, post-genomic times, systemic or holistic approaches to living phenomena are compulsory to overcome the limits of traditional strategies, such as the methodological reductionism of molecular biology. In this paper, we propose that theoretical and philosophical efforts to define life also contribute to those integrative approaches, providing a global theoretical framework that may help to deal with or interpret the huge amount of data being collected by current high-throughput technologies, in this so-called 'omics' revolution. We claim that two fundamental notions can capture the core of the living, (basic) autonomy and open-ended evolution, and that only the complementary combination of these two theoretical constructs offers an adequate solution to the problem of defining the nature of life in specific enough-but also encompassing enough-terms. This tentative solution should also illuminate, in its most elementary version, the leading steps towards living beings on Earth.

  9. Defining professional nursing accountability: a literature review.

    Science.gov (United States)

    Krautscheid, Lorretta C

    2014-01-01

    Professional nursing accountability is described by both professional nursing organizations and nursing education credentialing agencies as a core aspect that underpins professional nursing practice. Although accountability is foundational to professional practice, a review of the literature revealed no consistent language or definition regarding professional nursing accountability. Instead, the literature itself reveals that professional nursing accountability is challenging to both describe and define. The ambiguity surrounding how to define professional nursing accountability contributes to challenges associated with both teaching and evaluating student nurse accountability within nursing education curricula. This article provides a reliable and comprehensive definition of professional nursing accountability derived from a synthesis of the literature. Recommendations for nursing education practice and recommendations for nursing education research are proposed.

  10. Identity at work: Exploring strategies for Identity Work

    Directory of Open Access Journals (Sweden)

    Byron G. Adams

    2012-01-01

    Full Text Available Orientation: This study explored strategies for identity work that are central to the negotiation and regulation of employee work identity.Research purpose: The main aim of this study was to explore employee narratives and identify the strategies available to them in the process of identity work, as they defined themselves at work.Motivation for the study: As there is a scarcity of research on identity work in South Africa, this study wanted to advance knowledge about identity work and the strategies used for regulating and negotiating an identity at work by exploring these constructs in this context.Research design, approach and method: A qualitative research process formed the basis for this study. Nineteen employees from a global manufacturing company participated in two semi-structured in-depth interviews. Grounded theory was applied to analyse and interpret the data.Main findings: Nine strategies for identity work were identified and categorised into four broad themes (personal philosophies; relationships; career management and negotiating balance.Practical/managerial implications: Employees followed various strategies for defining themselves at work and this may have some implications for employee work engagement and productivity.Contribution/value-add: This study expands on current theoretical knowledge of identity work, and provides insights into the strategies people use to regulate and negotiate their identities at work

  11. Fingerprinting Software Defined Networks and Controllers

    Science.gov (United States)

    2015-03-01

    Department of Electrical and Computer Engineering Graduate School of Engineering and Management Air Force Institute of Technology Air University Air...Networking Defined Within a computer network, switching devices contain three abstractly organized services known as planes [9]. As shown in Figure 2.1, these...stations that exist within an exploitable network. The final threat vector is the lack of trusted resources for forensics and remediation for when an

  12. Research misconduct oversight: defining case costs.

    Science.gov (United States)

    Gammon, Elizabeth; Franzini, Luisa

    2013-01-01

    This study uses a sequential mixed method study design to define cost elements of research misconduct among faculty at academic medical centers. Using time driven activity based costing, the model estimates a per case cost for 17 cases of research misconduct reported by the Office of Research Integrity for the period of 2000-2005. Per case cost of research misconduct was found to range from $116,160 to $2,192,620. Research misconduct cost drivers are identified.

  13. Quantum Thought Experiments Can Define Nature

    CERN Document Server

    McCartor, D

    2004-01-01

    One would not think that thought experiments could matter to nature, for they are a humble human device. Yet quantum mechanics very naturally frames thought experiments (as distinct from precisely defining what exists). They exemplify the informing powers of radiation. Though based on wave functions that have time symmetry, these tableaux inevitably tell of irreversible behavior by nature. The paper sketches how John von Neumann's measurement theory fits into this and retells N. David Mermin's baseball story.

  14. Defining benzodiazepine dependence: The confusion persists

    OpenAIRE

    1995-01-01

    Little consensus exists on the risk of benzodiazepine (BZD) dependence. We investigated how often BZD dependence and related concepts have been defined in the literature on BZD effects in humans. In addition, the definitions of BZD dependence were compared in order to assess the similarity of contents. From a total of 250 papers (published between 1988 and 1991) 51 provided 126 dependence-related definitions. Six studies referred to the DSM definitions and one to the WHO definition. The obsol...

  15. Defining viability in mammalian cell cultures

    OpenAIRE

    Browne, Susan M.; Al-Rubeai, Mohamed

    2011-01-01

    Abstract A large number of assays are available to monitor viability in mammalian cell cultures with most defining loss of viability as a loss of plasma membrane integrity, a characteristic of necrotic cell death. However, the majority of cultured cells die by apoptosis and early apoptotic cells, although non-viable, maintain an intact plasma membrane and are thus ignored. Here we measure the viability of cultures of a number of common mammalian cell lines by assays that measure me...

  16. Thermodynamics. Using Affinities to define reversible processes

    CERN Document Server

    Ritacco, Hernán A

    2016-01-01

    In this article a definition of reversible processes in terms of differences in intensive Thermodynamics properties (Affinities) is proposed. This definition makes it possible to both define reversible processes before introducing the concept of entropy and avoid the circularity problem that follows from the Clausius definition of entropy changes. The convenience of this new definition compared to those commonly found in textbooks is demonstrated with examples.

  17. Precision volume measurement system.

    Energy Technology Data Exchange (ETDEWEB)

    Fischer, Erin E.; Shugard, Andrew D.

    2004-11-01

    A new precision volume measurement system based on a Kansas City Plant (KCP) design was built to support the volume measurement needs of the Gas Transfer Systems (GTS) department at Sandia National Labs (SNL) in California. An engineering study was undertaken to verify or refute KCP's claims of 0.5% accuracy. The study assesses the accuracy and precision of the system. The system uses the ideal gas law and precise pressure measurements (of low-pressure helium) in a temperature and computer controlled environment to ratio a known volume to an unknown volume.

  18. How Should Energy Be Defined Throughout Schooling?

    Science.gov (United States)

    Bächtold, Manuel

    2017-02-01

    The question of how to teach energy has been renewed by recent studies focusing on the learning and teaching progressions for this concept. In this context, one question has been, for the most part, overlooked: how should energy be defined throughout schooling? This paper addresses this question in three steps. We first identify and discuss two main approaches in physics concerning the definition of energy, one claiming there is no satisfactory definition and taking conservation as a fundamental property, and the other based on Rankine's definition of energy as the capacity of a system to produce changes. We then present a study concerning how energy is actually defined throughout schooling in the case of France by analyzing national programs, physics textbooks, and the answers of teachers to a questionnaire. This study brings to light a consistency problem in the way energy is defined across school years: in primary school, an adapted version of Rankine's definition is introduced and conservation is ignored; in high school, conservation is introduced and Rankine's definition is ignored. Finally, we address this consistency problem by discussing possible teaching progressions. We argue in favor of the use of Rankine's definition throughout schooling: at primary school, it is a possible substitute to students' erroneous conceptions; at secondary school, it might help students become aware of the unifying role of energy and thereby overcome the compartmentalization problem.

  19. Speciation without Pre-Defined Fitness Functions.

    Science.gov (United States)

    Gras, Robin; Golestani, Abbas; Hendry, Andrew P; Cristescu, Melania E

    2015-01-01

    The forces promoting and constraining speciation are often studied in theoretical models because the process is hard to observe, replicate, and manipulate in real organisms. Most models analyzed to date include pre-defined functions influencing fitness, leaving open the question of how speciation might proceed without these built-in determinants. To consider the process of speciation without pre-defined functions, we employ the individual-based ecosystem simulation platform EcoSim. The environment is initially uniform across space, and an evolving behavioural model then determines how prey consume resources and how predators consume prey. Simulations including natural selection (i.e., an evolving behavioural model that influences survival and reproduction) frequently led to strong and distinct phenotypic/genotypic clusters between which hybridization was low. This speciation was the result of divergence between spatially-localized clusters in the behavioural model, an emergent property of evolving ecological interactions. By contrast, simulations without natural selection (i.e., behavioural model turned off) but with spatial isolation (i.e., limited dispersal) produced weaker and overlapping clusters. Simulations without natural selection or spatial isolation (i.e., behaviour model turned off and high dispersal) did not generate clusters. These results confirm the role of natural selection in speciation by showing its importance even in the absence of pre-defined fitness functions.

  20. HIV-induced immunodeficiency and mortality from AIDS-defining and non-AIDS-defining malignancies

    NARCIS (Netherlands)

    Monforte, Antonella d'Arminio; Abrams, Donald; Pradier, Christian; Weber, Rainer; Reiss, Peter; Bonnet, Fabrice; Kirk, Ole; Law, Matthew; De Wit, Stephane; Friis-Møller, Nina; Phillips, Andrew N; Sabin, Caroline A; Lundgren, Jens D; Schölvinck, Elisabeth H.

    2008-01-01

    OBJECTIVE: To evaluate deaths from AIDS-defining malignancies (ADM) and non-AIDS-defining malignancies (nADM) in the D:A:D Study and to investigate the relationship between these deaths and immunodeficiency. DESIGN: Observational cohort study. METHODS: Patients (23 437) were followed prospectively f

  1. Shaping 3-D Volumes in Immersive Virtual Environments

    DEFF Research Database (Denmark)

    Stenholt, Rasmus

    Shaping 3-D volumes is an important part of many interactions in immersive virtual environments. The range of possible applications is wide. For instance, the ability to select objects in virtual environments is very often based on defin- ing and controlling a selection volume. This is especially...... true, if the intention is to select multiple objects. Another important application area is the manipula- tion of objects through the use of controllable handles, or widgets. Such widgets are often associated with a bounding volume around the object to be manipu- lated. Such techniques are both well...... of efficiently and precisely defining a 3-D box is a fundamental one to investigate. The first paper does this by analysing the practical task of defining a 3-D box as the equivalent task of defining its degrees- of-freedom. This analysis leads to the introduction of a new way of shaping a box from just three...

  2. Cosmic numbers the numbers that define our universe

    CERN Document Server

    Stein, James D

    2011-01-01

    Our fascination with numbers begins when we are children and continues throughout our lives. We start counting our fingers and toes and end up balancing checkbooks and calculating risk. So powerful is the appeal of numbers that many people ascribe to them a mystical significance. Other numbers go beyond the supernatural, working to explain our universe and how it behaves. In Cosmic Numbers , mathematics professor James D. Stein traces the discovery, evolution, and interrelationships of the numbers that define our world. Everyone knows about the speed of light and absolute zero, but numbers lik

  3. Work stress and risk of cancer

    DEFF Research Database (Denmark)

    Heikkilä, Katriina; Nyberg, Solja T; Theorell, Töres

    2013-01-01

    To investigate whether work related stress, measured and defined as job strain, is associated with the overall risk of cancer and the risk of colorectal, lung, breast, or prostate cancers.......To investigate whether work related stress, measured and defined as job strain, is associated with the overall risk of cancer and the risk of colorectal, lung, breast, or prostate cancers....

  4. THEORETICAL CLARIFICATIONS REGARDING THE CONCEPT OF WORKING CAPACITY OF WOOD-WORKING MACHINE-TOOLS

    Directory of Open Access Journals (Sweden)

    Gavril BUDĂU

    2014-09-01

    Full Text Available Due to persisting confusions between the concepts “labor productivity” and “working capacity” of a machine-tool, equipment or production line, the authors considered it necessary to define and explain these terms. Starting by defining the notions “working cycle” and “functioning cycle”, the paper details: the theoretical, technological and real working capacity and also the term “working time norm” for wood-working machine-tools.

  5. Paid work and unpaid work

    DEFF Research Database (Denmark)

    Bonke, Jens

    Time-use information is preferably obtained from diaries, as this method is considered more reliable than information from questionnaires. The diary-technique seems to be unique in catching the rhythm of every day life and thereby the structuring of work and leisure during a well......-questions are asked about the time spent on paid work and unpaid/household work. The advantage of the latter technique is that it can easily be integrated into surveys. Thus the American National Survey of Families and Households (NSFH) already contains two waves, and a new wave for 2001-2002, which allows...

  6. Contextual design defining customer-centered systems

    CERN Document Server

    Beyer, Hugh

    1997-01-01

    This book introduces a customer-centered approach to business by showing how data gathered from people while they work can drive the definition of a product or process while supporting the needs of teams and their organizations. This is a practical, hands-on guide for anyone trying to design systems that reflect the way customers want to do their work. The authors developed Contextual Design, the method discussed here, through their work with teams struggling to design products and internal systems. In this book, you'll find the underlying principles of the method and how to apply them to diff

  7. Saline volume expansion and cardiovascular physiology: novel observations, old explanations, and new questions.

    Science.gov (United States)

    Robotham, James L

    2004-10-01

    In a clinical investigation, Kumar and coworkers reported the hemodynamic events that accompany plasma volume expansion over 3 hours in healthy adult volunteers, and found that increases in stroke volume (SV) may be related to increases in left ventricular (LV)/right ventricular (RV) end-diastolic volume, as they expected, but also to decreases in LV/RV end-systolic volume. The latter finding suggests increased contractility and/or decreased afterload, which do not fit with their perception that clinicians ascribe increases in SV to increases in end-diastolic volume based on Starling's work. Increased ejection fraction and decreased vascular resistances were also observed. The same authors recently reported novel data suggesting that reduced blood viscosity may account for the observed reduction in vascular resistances with saline volume expansion. However, the variances in preload and afterload, along with uncertainty in estimates of contractility, substantially limit their ability to define a primary mechanism to explain decreases in LV end-systolic volume. A focus on using ejection fraction to evaluate the integrated performance of the cardiovascular system is provided to broaden this analytic perspective. Sagawa and colleagues described an approach to estimate the relationship, under clinical conditions, between ventricular and arterial bed elastances (i.e. maximal ventricular systolic elastance [Emax] and maximal arterial systolic elastance [Ea]), reflecting ventricular-arterial coupling. I used the mean data provided in one of the reports from Kumar and coworkers to calculate that LV Emax decreased from 1.09 to 0.96 mmHg/ml with saline volume expansion, while Ea decreased from 1.1 to 0.97 mmHg/ml and the SV increased (i.e. the increase in mean SV was associated with a decrease in mean afterload while the mean contractility decreased). The results reported by Kumar and coworkers invite further studies in normal and critically ill patients during acute saline

  8. Working Collaboratively

    DEFF Research Database (Denmark)

    Holder, Anna; Lovett, George

    2009-01-01

    Working collaboratively is arguably an essential skill in architectural practice as the complexity of contemporary projects involves multiple agents in the conception, construction and use of architecture. This has been emphasised by recent government rhetoric. Mass collaboration has been...... identified as a transformative global force of the last decade, most notably in knowledge and information publishing, communication and creation. This paper presents a structured conversation on changing understandings of collaboration, and the realities of collaborative methodology in architectural work....... Ideas of the platforms and structures necessary to support ‘creative’ collaborations are advanced and tested, and a vocabulary of key terms is developed. The conversation extends to reflect on the role of the architecture profession in supporting or enabling collaboration in architectural works....

  9. 29 CFR 779.107 - Goods defined.

    Science.gov (United States)

    2010-07-01

    ...; advertising, motion pictures, newspaper and radio copy; art work and manuscripts for publication; sample books, letterheads, envelopes, shipping tags, labels, checkbooks, blankbooks, book covers, advertising circulars, and... written materials such as newspapers, magazines, brochures, pamphlets, bulletins, and...

  10. Live ultrasound volume reconstruction using scout scanning

    Science.gov (United States)

    Meyer, Amelie; Lasso, Andras; Ungi, Tamas; Fichtinger, Gabor

    2015-03-01

    Ultrasound-guided interventions often necessitate scanning of deep-seated anatomical structures that may be hard to visualize. Visualization can be improved using reconstructed 3D ultrasound volumes. High-resolution 3D reconstruction of a large area during clinical interventions is challenging if the region of interest is unknown. We propose a two-stage scanning method allowing the user to perform quick low-resolution scouting followed by high-resolution live volume reconstruction. Scout scanning is accomplished by stacking 2D tracked ultrasound images into a low-resolution volume. Then, within a region of interest defined in the scout scan, live volume reconstruction can be performed by continuous scanning until sufficient image density is achieved. We implemented the workflow as a module of the open-source 3D Slicer application, within the SlicerIGT extension and building on the PLUS toolkit. Scout scanning is performed in a few seconds using 3 mm spacing to allow region of interest definition. Live reconstruction parameters are set to provide good image quality (0.5 mm spacing, hole filling enabled) and feedback is given during live scanning by regularly updated display of the reconstructed volume. Use of scout scanning may allow the physician to identify anatomical structures. Subsequent live volume reconstruction in a region of interest may assist in procedures such as targeting needle interventions or estimating brain shift during surgery.

  11. Bibliotherapy in social pedagogical work

    OpenAIRE

    Jelen, Tamara

    2013-01-01

    The thesis deals with bibliotherapy as an intervention, which can be used by social pedagogue in his work. Bibliotherapy is defined through its history and the areas where it is used, mainly in Slovenia. To understand the concept further there is a need for more detailed definition, therefore part is also dedicated to different forms of bibliotherapy, its goals and the process as defined by various authors and the comparison between them. But to explain bibliotherapy in the context of social ...

  12. Space shuttle main engine definition (phase B). Volume 5: Valves and interconnects. [for space shuttle

    Science.gov (United States)

    Schultz, D. F.

    1971-01-01

    The steady state thermodynamic cycle balance of the single preburner staged combustion engine, coupled with dynamic transient analyses, dictated in detail the location and requirements for each valve defined in this volume. Valve configuration selections were influenced by overall engine and vehicle system weight and failure mode determinations. Modulating valve actuators are external to the valve and are line replaceable. Development and satisfactory demonstration of a high pressure dynamic shaft seal has made this configuration practical. Pneumatic motor driven actuators that use engine pumped hydrogen gas as the working fluid are used. The helium control system is proposed as a module containing a cluster of solenoid actuated valves. The separable couplings and flanges are designed to assure minimum leakage with minimum coupling weight. The deflection of the seal surface in the flange is defined by finite element analysis that has been confirmed with test data. The seal design proposed has passed preliminary pressure cycling and thermal cycling tests.

  13. Defining the Value of Neurosurgery in the New Healthcare Era.

    Science.gov (United States)

    Benzil, Deborah L; Zusman, Edie E

    2017-04-01

    Healthcare delivery is evolving rapidly with an increasing emphasis on the concept of "value." At the same time, neurosurgeons are disproportionately working in employed positions where external definition of value becomes directly linked with compensation, work environment, and career satisfaction. Few neurosurgeons have an understanding of the various ways in which value is and can be defined and there are limited resources to assist in this realm. This paper covers the essential value concepts of National Standards, Pitfalls of National Standards, Call Coverage Compensation, Valuation Through Demand, Value Beyond Productivity, and Neurosurgical Value in the Accountable Care Organization Era. This framework should help neurosurgeons better understand critical trends impacting practice across the country. Copyright © 2017 by the Congress of Neurological Surgeons.

  14. Defining Scenarios: Linking Integrated Models, Regional Concerns, and Stakeholders

    Science.gov (United States)

    Hartmann, H. C.; Stewart, S.; Liu, Y.; Mahmoud, M.

    2007-05-01

    Scenarios are important tools for long-term planning, and there is great interest in using integrated models in scenario studies. However, scenario definition and assessment are creative, as well as scientific, efforts. Using facilitated creative processes, we have worked with stakeholders to define regionally significant scenarios that encompass a broad range of hydroclimatic, socioeconomic, and institutional dimensions. The regional scenarios subsequently inform the definition of local scenarios that work with context-specific integrated models that, individually, can address only a subset of overall regional complexity. Based on concerns of stakeholders in the semi-arid US Southwest, we prioritized three dimensions that are especially important, yet highly uncertain, for long-term planning: hydroclimatic conditions (increased variability, persistent drought), development patterns (urban consolidation, distributed rural development), and the nature of public institutions (stressed, proactive). Linking across real-world decision contexts and integrated modeling efforts poses challenges of creatively connecting the conceptual models held by both the research and stakeholder communities.

  15. Variable volume combustor

    Energy Technology Data Exchange (ETDEWEB)

    Ostebee, Heath Michael; Ziminsky, Willy Steve; Johnson, Thomas Edward; Keener, Christopher Paul

    2017-01-17

    The present application provides a variable volume combustor for use with a gas turbine engine. The variable volume combustor may include a liner, a number of micro-mixer fuel nozzles positioned within the liner, and a linear actuator so as to maneuver the micro-mixer fuel nozzles axially along the liner.

  16. Software Defined Radio: Basic Principles and Applications

    Directory of Open Access Journals (Sweden)

    José Raúl Machado-Fernández

    2014-12-01

    Full Text Available The author makes a review of the SDR (Software Defined Radio technology, including hardware schemes and application fields. A low performance device is presented and several tests are executed with it using free software. With the acquired experience, SDR employment opportunities are identified for low-cost solutions that can solve significant problems. In addition, a list of the most important frameworks related to the technology developed in the last years is offered, recommending the use of three of them.

  17. Software defined networks a comprehensive approach

    CERN Document Server

    Goransson, Paul

    2014-01-01

    Software Defined Networks discusses the historical networking environment that gave rise to SDN, as well as the latest advances in SDN technology. The book gives you the state of the art knowledge needed for successful deployment of an SDN, including: How to explain to the non-technical business decision makers in your organization the potential benefits, as well as the risks, in shifting parts of a network to the SDN modelHow to make intelligent decisions about when to integrate SDN technologies in a networkHow to decide if your organization should be developing its own SDN applications or

  18. Rates of Convergence of Recursively Defined Sequences

    DEFF Research Database (Denmark)

    Lambov, Branimir Zdravkov

    2005-01-01

    This paper gives a generalization of a result by Matiyasevich which gives explicit rates of convergence for monotone recursively defined sequences. The generalization is motivated by recent developments in fixed point theory and the search for applications of proof mining to the field. It relaxes...... the requirement for monotonicity to the form xn+1 ≤ (1+an)xn+bn where the parameter sequences have to be bounded in sum, and also provides means to treat computational errors. The paper also gives an example result, an application of proof mining to fixed point theory, that can be achieved by the means discussed...

  19. Healthcare Engineering Defined: A White Paper.

    Science.gov (United States)

    Chyu, Ming-Chien; Austin, Tony; Calisir, Fethi; Chanjaplammootil, Samuel; Davis, Mark J; Favela, Jesus; Gan, Heng; Gefen, Amit; Haddas, Ram; Hahn-Goldberg, Shoshana; Hornero, Roberto; Huang, Yu-Li; Jensen, Øystein; Jiang, Zhongwei; Katsanis, J S; Lee, Jeong-A; Lewis, Gladius; Lovell, Nigel H; Luebbers, Heinz-Theo; Morales, George G; Matis, Timothy; Matthews, Judith T; Mazur, Lukasz; Ng, Eddie Yin-Kwee; Oommen, K J; Ormand, Kevin; Rohde, Tarald; Sánchez-Morillo, Daniel; Sanz-Calcedo, Justo García; Sawan, Mohamad; Shen, Chwan-Li; Shieh, Jiann-Shing; Su, Chao-Ton; Sun, Lilly; Sun, Mingui; Sun, Yi; Tewolde, Senay N; Williams, Eric A; Yan, Chongjun; Zhang, Jiajie; Zhang, Yuan-Ting

    2015-01-01

    Engineering has been playing an important role in serving and advancing healthcare. The term "Healthcare Engineering" has been used by professional societies, universities, scientific authors, and the healthcare industry for decades. However, the definition of "Healthcare Engineering" remains ambiguous. The purpose of this position paper is to present a definition of Healthcare Engineering as an academic discipline, an area of research, a field of specialty, and a profession. Healthcare Engineering is defined in terms of what it is, who performs it, where it is performed, and how it is performed, including its purpose, scope, topics, synergy, education/training, contributions, and prospects.

  20. Defining Cyberbullying: A Multiple Perspectives Approach.

    Science.gov (United States)

    Alipan, Alexandra; Skues, Jason; Theiler, Stephen; Wise, Lisa

    2015-01-01

    To date, there has been a lack of consensus among researchers, practitioners, and laypersons about the definition of cyberbullying. Researchers have typically applied the key characteristics of intent to harm, power imbalance, and repetition from the definition of traditional bullying to cyberbullying, but how these characteristics transfer from the real world to a technology-mediated environment remains ambiguous. Moreover, very few studies have specifically investigated how cyberbullying is defined from the perspective of bullies, victims and bystanders. To this end, this article will propose a three-part definition of cyberbullying, which incorporates the perspective of bullies, victims and bystanders.

  1. UNIQLO,Define Your Own Fashion

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    Yes,women like and enjoy shopping.Always,they want to buy some well-designed clothes with the most ‘in’ factors;and what’s of the great importance,they would like to hear the words:"wow! You fit the wear well!" However,the most satisfied right things could not be always waiting for you thereory ou would not help complaining the so-fast changing trends day by day.At that time,why not to seek some delights from the basic classic collections? UNIQLO maybe is a choice for you to define youro wn fashion.

  2. Defining Starch Binding by Glucan Phosphatases

    DEFF Research Database (Denmark)

    Auger, Kyle; Raththagala, Madushi; Wilkens, Casper

    2015-01-01

    phosphatases. The main objective of this study was to quantify the binding affinity of different enzymes that are involved in this cyclic process. We established a protocol to quickly, reproducibly, and quantitatively measure the binding of the enzymes to glucans utilizing Affinity Gel Electrophoresis (AGE...... glucan phosphatases showed similar affinities for the short oligosaccharide β-cyclodextrin. We performed structure-guided mutagenesis to define the mechanism of these differences. We found that the carbohydrate binding module (CBM) domain provided a stronger binding affinity compared to surface binding...

  3. Defining Requirements for Improved Photovoltaic System Reliability

    Energy Technology Data Exchange (ETDEWEB)

    Maish, A.B.

    1998-12-21

    Reliable systems are an essential ingredient of any technology progressing toward commercial maturity and large-scale deployment. This paper defines reliability as meeting system fictional requirements, and then develops a framework to understand and quantify photovoltaic system reliability based on initial and ongoing costs and system value. The core elements necessary to achieve reliable PV systems are reviewed. These include appropriate system design, satisfactory component reliability, and proper installation and servicing. Reliability status, key issues, and present needs in system reliability are summarized for four application sectors.

  4. Languages for Software-Defined Networks

    Science.gov (United States)

    2013-02-01

    1 Languages for Software-Defined Networks Nate Foster∗, Michael J. Freedman†, Arjun Guha∗, Rob Harrison‡, Naga Praveen Katta†, Christopher Monsanto ...2012. [12] “The Frenetic project.” http://www.frenetic-lang.org/, Sept. 2012. [13] N. Foster, R. Harrison, M. J. Freedman, C. Monsanto , J. Rexford...performance networks,” in ACM SIGCOMM, pp. 254–265, Aug. 2011. [15] C. Monsanto , N. Foster, R. Harrison, and D. Walker, “A compiler and run-time system for

  5. Healthcare Engineering Defined: A White Paper

    Directory of Open Access Journals (Sweden)

    Ming-Chien Chyu

    2015-01-01

    Full Text Available Engineering has been playing an important role in serving and advancing healthcare. The term “Healthcare Engineering” has been used by professional societies, universities, scientific authors, and the healthcare industry for decades. However, the definition of “Healthcare Engineering” remains ambiguous. The purpose of this position paper is to present a definition of Healthcare Engineering as an academic discipline, an area of research, a field of specialty, and a profession. Healthcare Engineering is defined in terms of what it is, who performs it, where it is performed, and how it is performed, including its purpose, scope, topics, synergy, education/training, contributions, and prospects.

  6. Delta Semantics Defined By Petri Nets

    DEFF Research Database (Denmark)

    Jensen, Kurt; Kyng, Morten; Madsen, Ole Lehrmann

    This report is identical to an earlier version of May 1978 except that Chapter 5 has been revised. A new paper: "A Petri Net Definition of a System Description Language", DAIMI, April 1979, 20 pages, extends the Petri net model to include a data state representing the program variables. Delta...... and the possibility of using predicates to specify state changes. In this paper a formal semantics for Delta is defined and analysed using Petri nets. Petri nets was chosen because the ideas behind Petri nets and Delta concide on several points. A number of proposals for changes in Delta, which resulted from...

  7. Defining recovery in adult bulimia nervosa.

    Science.gov (United States)

    Yu, Jessica; Agras, W Stewart; Bryson, Susan

    2013-01-01

    To examine how different definitions of recovery lead to varying rates of recovery, maintenance of recovery, and relapse in bulimia nervosa (BN), end-of-treatment (EOT) and follow-up data were obtained from 96 adults with BN. Combining behavioral, physical, and psychological criteria led to recovery rates between 15.5% and 34.4% at EOT, though relapse was approximately 50%. Combining these criteria and requiring abstinence from binge eating and purging when defining recovery may lead to lower recovery rates than those found in previous studies; however, a strength of this definition is that individuals who meet this criteria have no remaining disordered behaviors or symptoms.

  8. Volume Regulated Channels

    DEFF Research Database (Denmark)

    Klausen, Thomas Kjær

    of volume perturbations evolution have developed system of channels and transporters to tightly control volume homeostasis. In the past decades evidence has been mounting, that the importance of these volume regulated channels and transporters are not restricted to the defense of cellular volume...... but are also essential for a number of physiological processes such as proliferation, controlled cell death, migration and endocrinology. The thesis have been focusing on two Channels, namely the swelling activated Cl- channel (ICl, swell) and the transient receptor potential Vanilloid (TRPV4) channel. I: Cl......- serves a multitude of functions in the mammalian cell, regulating the membrane potential (Em), cell volume, protein activity and the driving force for facilitated transporters giving Cl- and Cl- channels a major potential of regulating cellular function. These functions include control of the cell cycle...

  9. Work sampling

    OpenAIRE

    Salas Bacalla, julio; FII-UNMSM

    2014-01-01

    Work sampling is a method of indirect measurement, which means instantaneous observations, to determine the amount of uptime or downtime in a production process El muestreo de trabajo es un método de medición indirecto, que mediante observaciones instantaneas, permite determinar la cantidad de tiempo en actividad o inactividad en un proceso productivo

  10. Hard work

    NARCIS (Netherlands)

    Myra Keizer; Saskia Keuzenkamp

    2011-01-01

    Original title: Moeilijk werken More than one in ten women say they are not available for the labour market because of health complaints. That is almost twice as many as the figure for men. Migrant women, in particular, often cite health as a reason for not being able to work. Are there

  11. Demolition work

    CERN Document Server

    2004-01-01

    Because of demolition work inside Bldg. 251, two containers will be placed on the route Démocrite. For security reasons, the part of this road in front of barrack 553 will be closed to circulation from 5 to 12 November. Thank you, in advance for your understanding. PH-SMI

  12. Road works

    CERN Multimedia

    GS Department

    2010-01-01

    From Monday 11 October until Friday 29 October 2010, the flow of traffic will be disrupted by road works at the roundabout in front of Restaurant No. 2; The number of spaces available in the car park in front of Rest. No. 2 will be reduced. Thank you for your understanding during this period. GS/SEM Group

  13. Wetlands Work

    Science.gov (United States)

    Messina, Linda; Blanchard, Pamela Borne

    2004-01-01

    This article describes how a biology teacher's search for a cross-curricular project in science, math, history, and environmental science, that would help her students connect what they were learning in the classroom to their everyday life, resulted in an ongoing stewardship project. Working together with the Louisiana Sea Grant College Program…

  14. Wetlands Work

    Science.gov (United States)

    Messina, Linda; Blanchard, Pamela Borne

    2004-01-01

    This article describes how a biology teacher's search for a cross-curricular project in science, math, history, and environmental science, that would help her students connect what they were learning in the classroom to their everyday life, resulted in an ongoing stewardship project. Working together with the Louisiana Sea Grant College Program…

  15. Working Parents

    Science.gov (United States)

    ... on your time and energy. For example, the family can work together to clean up the kitchen after dinner; with everyone's help it will get done much quicker and free up some time for you in the evening. Do the same on the ... build family cohesiveness while finishing the job faster, thus leaving ...

  16. Construction work

    CERN Multimedia

    2004-01-01

    Construction work on building 179 will start on the 16th February 2004 and continue until November 2004. The road between buildings 179 and 158 will temporarily become a one way street from Route Democrite towards building 7. The parking places between buildings 179 and 7 will become obsolete. The ISOLDE collaboration would like to apologize for any inconveniences.

  17. Defining Coherent Vortices Objectively from the Vorticity

    CERN Document Server

    Haller, George; Farazmand, Mohammad; Huhn, Florian

    2015-01-01

    Rotationally coherent Lagrangian vortices are formed by tubes of deforming fluid elements that complete equal bulk material rotation relative to the mean rotation of the deforming fluid volume. We show that initial positions of such tubes coincide with tubular level surfaces of the Lagrangian-Averaged Vorticity Deviation (LAVD), the trajectory integral of the normed difference of the vorticity from its spatial mean. LAVD-based vortices are objective, i.e., remain unchanged under time-dependent rotations and translations of the coordinate frame. In the limit of vanishing Rossby numbers in geostrophic flows, cyclonic LAVD vortex centers are precisely the observed attractors for light particles. A similar result holds for heavy particles in anticyclonic LAVD vortices. We also establish a relationship between rotationally coherent Lagrangian vortices and their instantaneous Eulerian counterparts. The latter are formed by tubular surfaces of equal material rotation rate, objectively measured by the Instantaneous V...

  18. What makes a successful volume crime investigator?

    OpenAIRE

    2011-01-01

    This exploratory study sought to understand the role of volume crime investigators in the modern era. It attempted to gain officers` perceptions on the attributes required to be a successful at the role. In addition, the research sought to understand how modern investigators thought success should be defined and measured in relation to individual investigator performance. Chapter One explored previous research relating to police investigators and success, and identified the main research que...

  19. Work and minor work contracts

    CERN Document Server

    1999-01-01

    The Work and Minor Work contracts are all of the result-oriented type. The work is specified by CERN and the contractor is given full responsibility for its performance. The contracts are thus very similar to supply contracts. The re-tendering of the existing contracts is almost complete, except for some building maintenance contracts. A new cycle of re-tendering for some activities will be launched in the next twelve months. The total estimated expenditure in the year 2000 for the contracts referred to in this document is 27 750 000 Swiss francs at 1999 prices. The Finance Committee is invited: - to approve the proposed expenditure for the extension of contracts for which the estimated amount for the year 2000 exceeds 750 000 Swiss francs, namely those under references 1, 2, 3, 5, 7, 8, 9 and 23, highlighted in Table I; - to take note that all Work and Minor Work contracts have been tendered since 1 January 1994, except the small contracts shown under references 12 and 16 in Table I; - to take note that the ...

  20. Blended working: for whom it may (not work.

    Directory of Open Access Journals (Sweden)

    Nico W Van Yperen

    Full Text Available Similarly to related developments such as blended learning and blended care, blended working is a pervasive and booming trend in modern societies. Blended working combines on-site and off-site working in an optimal way to improve workers' and organizations' outcomes. In this paper, we examine the degree to which workers feel that the two defining features of blended working (i.e., time-independent working and location-independent working enhance their own functioning in their jobs. Blended working, enabled through the continuing advance and improvement of high-tech ICT software, devices, and infrastructure, may be considered beneficial for workers' perceived effectiveness because it increases their job autonomy. However, because blended working may have downsides as well, it is important to know for whom blended working may (not work. As hypothesized, in a sample of 348 workers (51.7% women, representing a wide range of occupations and organizations, we found that the perceived personal effectiveness of blended working was contingent upon workers' psychological need strength. Specifically, the perceived effectiveness of both time-independent working and location-independent working was positively related to individuals' need for autonomy at work, and negatively related to their need for relatedness and need for structure at work.

  1. Granger Lake, Embankment-Outlet Works-Spillway. Volume 2.

    Science.gov (United States)

    1983-08-01

    Sr Z/ 3d APE \\1F. 7sI Ef- N ago -~~~~T AC-, It 6 9 10 oO"o A* t. eAV -- 1 -A Lk .1. I A A. c, . -..-.- -. V v v E NC -.I 0 AULIEX Af~l. ’r 4. A- GEE Dl...be TYPICAL SECTIONS ,verb-, if to comoersafe for srft:e-erf afp’er eon. _p e zo. rig of e,,b ,k,-eC, 1 15 aoo-ox -a-’ 1, no( deseed , ’蔿 11O3C ~ -. 3

  2. The Defining Characteristics of Urban Living Labs

    Directory of Open Access Journals (Sweden)

    Kris Steen

    2017-07-01

    Full Text Available The organization of supported and sustainable urban interventions is challenging, with multiple actors involved, fragmented decision-making powers, and multiple values at stake. Globally, urban living labs have become a fashionable phenomenon to tackle this challenge, fostering the development and implementation of innovation, experimentation, and knowledge in urban, real-life settings while emphasizing the important role of participation and co-creation. However, although urban living labs could in this way help cities to speed up the sustainable transition, urban living lab experts agree that, in order to truly succeed in these ambitious tasks, the way urban living labs are being shaped and steered needs further research. Yet, they also confirm the existing variation and opaqueness in the definition of the concept. This article contributes to conceptual clarity by developing an operationalized definition of urban living labs, which has been used to assess 90 sustainable urban innovation projects in the city of Amsterdam. The assessment shows that the majority of the projects that are labelled as living labs do not include one or more of the defining elements of a living lab. In particular, the defining co-creation and development activities were found to be absent in many of the projects. This article makes it possible to categorize alleged living lab projects and distill the “true” living labs from the many improperly labelled or unlabelled living labs, allowing more specific analyses and, ultimately, better targeted methodological recommendations for urban living labs.

  3. COMMENSURABLE ENCRYPTION USING USER- DEFINE KEY TECHNIQUE

    Directory of Open Access Journals (Sweden)

    ripal dilipbhai ranpara

    2012-11-01

    Full Text Available Cryptography is the gold standard for security. It is used to protect the transmission and storage of data between two parties by encrypting it into an unreadable format. Cryptography has enabled the first wave of secure transmissions, which has helped fuel the growth of transactions like shopping, banking, and finance over the world’s biggest public network, the Internet. Many Internet applications such as e-mail, databases, and browsers store a tremendous amount of personal and financial information, but frequently the data is left unprotected. Traditional network security is frequently less effective at preventing hackers from accessing this data. For instance, once-private databases are now completely exposed on the Internet. It turns out that getting to the database that holds millions of credit card numbers—the transmission—is secure through the use of cryptography, but the database itself isn’t, fueling the rise of credit card information theft. A paradigm shift is now under way for cryptography. The only way to make data secure in any application that runs over the Internet is to use secret (also known as private key cryptography. The current security methods focus on securing Internet applications using public keys techniques that are no longer effective.so according to my knowledge no one has addressed on COMMENSURABLE USER-DEFINE KEY TECHNIQUE that is used to encrypt the data as per the user-define key

  4. Using experimental design to define boundary manikins.

    Science.gov (United States)

    Bertilsson, Erik; Högberg, Dan; Hanson, Lars

    2012-01-01

    When evaluating human-machine interaction it is central to consider anthropometric diversity to ensure intended accommodation levels. A well-known method is the use of boundary cases where manikins with extreme but likely measurement combinations are derived by mathematical treatment of anthropometric data. The supposition by that method is that the use of these manikins will facilitate accommodation of the expected part of the total, less extreme, population. In literature sources there are differences in how many and in what way these manikins should be defined. A similar field to the boundary case method is the use of experimental design in where relationships between affecting factors of a process is studied by a systematic approach. This paper examines the possibilities to adopt methodology used in experimental design to define a group of manikins. Different experimental designs were adopted to be used together with a confidence region and its axes. The result from the study shows that it is possible to adapt the methodology of experimental design when creating groups of manikins. The size of these groups of manikins depends heavily on the number of key measurements but also on the type of chosen experimental design.

  5. Defining professional pharmacy services in community pharmacy.

    Science.gov (United States)

    Moullin, Joanna C; Sabater-Hernández, Daniel; Fernandez-Llimos, Fernando; Benrimoj, Shalom I

    2013-01-01

    Multiple terms and definitions exist to describe specific aspects of pharmacy practice and service provision, yet none encompass the full range of professional services delivered by community pharmacy. The majority of current pharmacy service definitions and nomenclature refer to either the professional philosophy of pharmaceutical care or to specific professional pharmacy services; particularly pharmaceutical services provided by pharmacists with a focus on drug safety, effectiveness and health outcomes. The objective of this paper is therefore to define a professional pharmacy service within the context of the community pharmacy model of service provision. A professional pharmacy service is defined as "an action or set of actions undertaken in or organised by a pharmacy, delivered by a pharmacist or other health practitioner, who applies their specialised health knowledge personally or via an intermediary, with a patient/client, population or other health professional, to optimise the process of care, with the aim to improve health outcomes and the value of healthcare." Based on Donabedian's framework, the professional pharmacy service definition incorporates the concepts of organizational structure, process indicators and outcome measures. The definition will assist in many areas including recognition of the full range of services provided by community pharmacy and facilitating the identification of indicators of professional pharmacy service implementation and sustainable provision. A simple conceptual model for incorporating all services provided by community pharmacy is proposed. Copyright © 2013 Elsevier Inc. All rights reserved.

  6. Medical abortion. defining success and categorizing failures

    DEFF Research Database (Denmark)

    Rørbye, Christina; Nørgaard, Mogens; Vestermark, Vibeke

    2003-01-01

    Medical abortion was performed in 461 consecutive women with gestational age LT /= 63 days using a regimen of mifepristone 600 mg followed 2 days later by gemeprost 1 mg vaginally. Success, defined as no surgical intervention, declined from 98.7% after 2 weeks to 94.6% after 15 weeks. The differe......Medical abortion was performed in 461 consecutive women with gestational age LT /= 63 days using a regimen of mifepristone 600 mg followed 2 days later by gemeprost 1 mg vaginally. Success, defined as no surgical intervention, declined from 98.7% after 2 weeks to 94.6% after 15 weeks....... The difference in short- and long-term success rates increased with increasing gestational age. The majority of failures (76%) were diagnosed more than 2 weeks after initiation of the abortion. At a 2-week follow-up visit, the women who turned out to be failures had a larger endometrial width, higher beta......-hCG values and smaller reductions of beta-hCG than those treated successfully. To optimize comparison of success rates after different medical abortion regimens, we suggest that the criteria for success are stated clearly, that the success rates are stratified according to gestational age...

  7. Programmatic methods for addressing contaminated volume uncertainties.

    Energy Technology Data Exchange (ETDEWEB)

    DURHAM, L.A.; JOHNSON, R.L.; RIEMAN, C.R.; SPECTOR, H.L.; Environmental Science Division; U.S. ARMY CORPS OF ENGINEERS BUFFALO DISTRICT

    2007-01-01

    Accurate estimates of the volumes of contaminated soils or sediments are critical to effective program planning and to successfully designing and implementing remedial actions. Unfortunately, data available to support the preremedial design are often sparse and insufficient for accurately estimating contaminated soil volumes, resulting in significant uncertainty associated with these volume estimates. The uncertainty in the soil volume estimates significantly contributes to the uncertainty in the overall project cost estimates, especially since excavation and off-site disposal are the primary cost items in soil remedial action projects. The Army Corps of Engineers Buffalo District's experience has been that historical contaminated soil volume estimates developed under the Formerly Utilized Sites Remedial Action Program (FUSRAP) often underestimated the actual volume of subsurface contaminated soils requiring excavation during the course of a remedial activity. In response, the Buffalo District has adopted a variety of programmatic methods for addressing contaminated volume uncertainties. These include developing final status survey protocols prior to remedial design, explicitly estimating the uncertainty associated with volume estimates, investing in predesign data collection to reduce volume uncertainties, and incorporating dynamic work strategies and real-time analytics in predesign characterization and remediation activities. This paper describes some of these experiences in greater detail, drawing from the knowledge gained at Ashland1, Ashland2, Linde, and Rattlesnake Creek. In the case of Rattlesnake Creek, these approaches provided the Buffalo District with an accurate predesign contaminated volume estimate and resulted in one of the first successful FUSRAP fixed-price remediation contracts for the Buffalo District.

  8. Lower bounds on volumes of hyperbolic Haken 3-manifolds

    Science.gov (United States)

    Agol, Ian; Storm, Peter A.; Thurston, William P.

    2007-10-01

    We prove a volume inequality for 3-manifolds having C^{0} metrics ``bent'' along a surface and satisfying certain curvature conditions. The result makes use of Perelman's work on the Ricci flow and geometrization of closed 3-manifolds. Corollaries include a new proof of a conjecture of Bonahon about volumes of convex cores of Kleinian groups, improved volume estimates for certain Haken hyperbolic 3-manifolds, and a lower bound on the minimal volume of orientable hyperbolic 3-manifolds. An appendix compares estimates of volumes of hyperbolic 3-manifolds drilled along a closed embedded geodesic with experimental data.

  9. Defining the role of laboratory genetic counselor.

    Science.gov (United States)

    Christian, Susan; Lilley, Margaret; Hume, Stacey; Scott, Patrick; Somerville, Martin

    2012-08-01

    An increasing number of genetic counselors are moving into non-clinical roles, where their primary duties do not involve direct patient contact. According to the National Society of Genetic Counselors Professional Status Survey in 2010, 23% of counselors working in non-clinical roles identified laboratory or genetic testing as their primary area of work. Using a survey, we identified 43 genetic counselors who work predominately in laboratory settings. The two primary tasks performed by participants, include acting as a customer liaison (95%) and calling out test results (88%). Nineteen participants (44.2%) also reported spending a considerable amount of time signing reports. The most prevalent areas of job satisfaction were support from laboratory directors (76.8%), autonomy (76.7%), interactions with clinicians (69.7%) and interaction with other genetics counselors (67.5%). This is the first study specifically looking at the roles of laboratory genetic counselors, which is an expanding area of genetic counseling.

  10. Sex Differences in Mental Arithmetic, Digit Span, and "g" Defined as Working Memory Capacity

    Science.gov (United States)

    Lynn, Richard; Irwing, Paul

    2008-01-01

    Meta-analyses are presented of sex differences in (1) the (mental) arithmetic subtest of the Wechsler intelligence tests for children and adolescents (the WISC and WPPSI tests), showing that boys obtained a mean advantage of 0.11d; (2) the (mental) arithmetic subtest of the Wechsler intelligence tests for adults (the WAIS tests) showing a mean…

  11. Defining Equivalence in Medical Education Evaluation and Research: Does a Distribution-Based Approach Work?

    Science.gov (United States)

    Rusticus, Shayna A.; Eva, Kevin W.

    2016-01-01

    Educators often seek to demonstrate the equivalence of groups, such as whether or not students achieve comparable success regardless of the site at which they trained. A methodological consideration that is often underappreciated is how to operationalize equivalence. This study examined whether a distribution-based approach, based on effect size,…

  12. Remedial investigation work plan for Bear Creek Valley Operable Unit 1 (S-3 Ponds, Boneyard/Burnyard, Oil Landfarm, Sanitary Landfill 1, and the Burial Grounds, including Oil Retention Ponds 1 and 2) at the Oak Ridge Y-12 Plant, Oak Ridge, Tennessee. Volume 1, Main text

    Energy Technology Data Exchange (ETDEWEB)

    1993-09-01

    The intent and scope of the work plan are to assemble all data necessary to facilitate selection of remediation alternatives for the sites in Bear Creek Valley Operable Unit 1 (BCV OU 1) such that the risk to human health and the environment is reduced to acceptable levels based on agreements with regulators. The ultimate goal is to develop a final Record Of Decision (ROD) for all of the OUs in BCV, including the integrator OU. However, the initial aim of the source OUs is to develop a ROD for interim measures. For source OUs such as BCV OU 1, data acquisition will not be carried out in a single event, but will be carried out in three stages that accommodate the schedule for developing a ROD for interim measures and the final site-wide ROD. The three stages are as follows: Stage 1, Assemble sufficient data to support decisions such as the need for removal actions, whether to continue with the remedial investigation (RI) process, or whether no further action is required. If the decision is made to continue the RI/FS process, then: Stage 2, Assemble sufficient data to allow for a ROD for interim measures that reduce risks to the human health and the environment. Stage 3, Provide input from the source OU that allows a final ROD to be issued for all OUs in the BCV hydrologic regime. One goal of the RI work plan will be to ensure that sampling operations required for the initial stage are not repeated at later stages. The overall goals of this RI are to define the nature and extent of contamination so that the impact of leachate, surface water runoff, and sediment from the OU I sites on the integrator OU can be evaluated, the risk to human health and the environment can be defined, and the general physical characteristics of the subsurface can be determined such that remedial alternatives can be screened.

  13. RESUMING WORK

    CERN Multimedia

    Service Médical

    2000-01-01

    In application of the Staff Rules and Regulations, every member of the CERN personnel is required to undergo a medical examination on resuming work after sick leave: - if the medical absence has been for 21 calendar days or longer, - if absent more than 48 hours due to professional accident. It is incumbent upon the member of the personnel himself/herself to contact the Medical Service 73186, without awaiting its summons.

  14. Works notice

    CERN Multimedia

    GS Department

    2009-01-01

    We would like to inform you that renovation work on the road lighting equipment will take place on the Meyrin site between 19 October and 18 December 2009. During this period, traffic will be disrupted on the Schrödinger, Perrin and Siegbahn roads, ie from Building 274 to Building 188. We request that you comply with the road signs and thank you for your understanding. GS-SEM Group

  15. RESUMING WORK

    CERN Multimedia

    Medical Service

    2001-01-01

    In application of the Staff Rules and Regulations, every member of the CERN personnel is required to undergo a medical examination on resuming work after sick leave: if the medical absence has been for 21 calendar days or longer, if absent more than 48 hours due to professional accident. It is incumbent upon the member of the personnel himself/herself to contact the Medical Service 73186, without awaiting its summons.

  16. RESUMING WORK

    CERN Multimedia

    Medical Service

    2002-01-01

    In application of the Staff Rules and Regulations, every member of the CERN personnel is required to undergo a medical examination on resuming work after sick leave: if the medical absence has been for 21 calendar days or longer, if absent more than 48 hours due to professional accident. It is incumbent upon the member of the personnel himself/herself to contact the Medical Service 73186, without awaiting its summons. Medical Service

  17. RESUMING WORK

    CERN Multimedia

    Service Médical

    2000-01-01

    In application of the Staff Rules and Regulations, every member of the CERN personnel is required to undergo a medical examination on resuming work after sick leave: if the medical absence has been for 21 calendar days or longer, if absent more than 48 hours due to professional accident. It is incumbent upon the member of the personnel himself/herself to contact the Medical Service 73186, without awaiting its summons.

  18. RESUMING WORK

    CERN Multimedia

    Medical Service

    2002-01-01

    In application of the Staff Rules and Regulations, every member of the CERN personnel is required to undergo a medical examination on resuming work after sick leave: if the medical absence has been for 21 calendar days or longer, if absent more than 48 hours due to professional accident. It is incumbent upon the member of the personnel himself/herself to contact the Medical Service 73186, without awaiting its summons. Medical Service

  19. NOTE Thyroid volume measurement in external beam radiotherapy patients using CT imaging: correlation with clinical and anthropometric characteristics

    Science.gov (United States)

    Veres, C.; Garsi, J. P.; Rubino, C.; Pouzoulet, F.; Bidault, F.; Chavaudra, J.; Bridier, A.; Ricard, M.; Ferreira, I.; Lefkopoulos, D.; de Vathaire, F.; Diallo, I.

    2010-11-01

    The aim of this study is to define criteria for accurate representation of the thyroid in human models used to represent external beam radiotherapy (EBRT) patients and evaluate the relationship between the volume of this organ and clinical and anthropometric characteristics. From CT images, we segmented the thyroid gland and calculated its volume for a population of 188 EBRT patients of both sexes, with ages ranging from 1 to 89 years. To evaluate uncertainties linked to measured volumes, experimental studies on the Livermore anthropomorphic phantom were performed. For our population of EBRT patients, we observed that in children, thyroid volume increased rapidly with age, from about 3 cm3 at 2 years to about 16 cm3 at 20. In adults, the mean thyroid gland volume was 23.5 ± 9 cm3 for males and 17.5 ± 8 cm3 for females. According to anthropometric parameters, the best fit for children was obtained by modeling the log of thyroid volume as a linear function of body surface area (BSA) (p < 0.0001) and age (p = 0.04) and for adults, as a linear function of BSA (p < 0.0001) and gender (p = 0.01). This work enabled us to demonstrate that BSA was the best indicator of thyroid volume for both males and females. These results should be taken into account when modeling the volume of the thyroid in human models used to represent EBRT patients for dosimetry in retrospective studies of the relationship between the estimated dose to the thyroid and long-term follow-up data on EBRT patients.

  20. Thyroid volume measurement in external beam radiotherapy patients using CT imaging: correlation with clinical and anthropometric characteristics

    Energy Technology Data Exchange (ETDEWEB)

    Veres, C; Garsi, J P; Rubino, C; De Vathaire, F; Diallo, I [Inserm, CESP Centre for research in Epidemiology and Population Health, U1018, Radiation Epidemiology Team, F 94807, Villejuif (France); Pouzoulet, F; Bidault, F; Chavaudra, J; Bridier, A; Ricard, M; Ferreira, I; Lefkopoulos, D, E-mail: ibrahim.diallo@igr.f [Institut Gustave Roussy, F-94805, Villejuif (France)

    2010-11-07

    The aim of this study is to define criteria for accurate representation of the thyroid in human models used to represent external beam radiotherapy (EBRT) patients and evaluate the relationship between the volume of this organ and clinical and anthropometric characteristics. From CT images, we segmented the thyroid gland and calculated its volume for a population of 188 EBRT patients of both sexes, with ages ranging from 1 to 89 years. To evaluate uncertainties linked to measured volumes, experimental studies on the Livermore anthropomorphic phantom were performed. For our population of EBRT patients, we observed that in children, thyroid volume increased rapidly with age, from about 3 cm{sup 3} at 2 years to about 16 cm{sup 3} at 20. In adults, the mean thyroid gland volume was 23.5 {+-} 9 cm{sup 3} for males and 17.5 {+-} 8 cm{sup 3} for females. According to anthropometric parameters, the best fit for children was obtained by modeling the log of thyroid volume as a linear function of body surface area (BSA) (p < 0.0001) and age (p = 0.04) and for adults, as a linear function of BSA (p < 0.0001) and gender (p = 0.01). This work enabled us to demonstrate that BSA was the best indicator of thyroid volume for both males and females. These results should be taken into account when modeling the volume of the thyroid in human models used to represent EBRT patients for dosimetry in retrospective studies of the relationship between the estimated dose to the thyroid and long-term follow-up data on EBRT patients. (note)

  1. Volume regulation in epithelia

    DEFF Research Database (Denmark)

    Larsen, Erik Hviid; Hoffmann, Else Kay

    2016-01-01

    function of iso-osmotic fluid transport that depends on Na+ recirculation. The causative relationship is discussed for a fluid-absorbing and a fluid-secreting epithelium of which the Na+ recirculation mechanisms have been identified. A large number of transporters and ion channels involved in cell volume...... regulation are cloned. The volume-regulated anion channel (VRAC) exhibiting specific electrophysiological characteristics seems exclusive to serve cell volume regulation. This is contrary to K+ channels as well as cotransporters and exchange mechanisms that may serve both transepithelial transport and cell...

  2. Towards the Amplituhedron Volume

    CERN Document Server

    Ferro, Livia; Orta, Andrea; Parisi, Matteo

    2015-01-01

    It has been recently conjectured that scattering amplitudes in planar N=4 super Yang-Mills are given by the volume of the (dual) amplituhedron. In this paper we show some interesting connections between the tree-level amplituhedron and a special class of differential equations. In particular we demonstrate how the amplituhedron volume for NMHV amplitudes is determined by these differential equations. The new formulation allows for a straightforward geometric description, without any reference to triangulations. Finally we discuss possible implications for volumes related to generic N^kMHV amplitudes.

  3. Unsteady flow volumes

    Energy Technology Data Exchange (ETDEWEB)

    Becker, B.G.; Lane, D.A.; Max, N.L.

    1995-03-01

    Flow volumes are extended for use in unsteady (time-dependent) flows. The resulting unsteady flow volumes are the 3 dimensional analog of streamlines. There are few examples where methods other than particle tracing have been used to visualize time varying flows. Since particle paths can become convoluted in time there are additional considerations to be made when extending any visualization technique to unsteady flows. We will present some solutions to the problems which occur in subdivision, rendering, and system design. We will apply the unsteady flow volumes to a variety of field types including moving multi-zoned curvilinear grids.

  4. Bronchoscopic lung volume reduction

    Directory of Open Access Journals (Sweden)

    M. I. Polkey

    2006-12-01

    Full Text Available Surgical lung volume reduction can improve exercise performance and forced expiratory volume in one second in patients with emphysema. However, the procedure is associated with a 5% mortality rate and a nonresponse rate of 25%. Accordingly, interest has focused on alternative ways of reducing lung volume. Two principle approaches are used: collapse of the diseased area using blockers placed endobronchially and the creation of extrapulmonary pathways. Preliminary data from the former approach suggest that it can be successful and that the magnitude of success is related to reduction in dynamic hyperinflation.

  5. Defining stakeholder involvement in participatory design processes

    NARCIS (Netherlands)

    Vink, P.; Imada, A.S.; Zink, K.J.

    2008-01-01

    A participatory approach could be used to implement work place or organizational improvements. However, the question is which participants should be involved and how. In this paper the theoretical involvement in different steps of a linear stepwise approach is described and compared with the latest

  6. The Territory of Literature: Defining the Coastline.

    Science.gov (United States)

    Naidoo, Beverly

    1994-01-01

    Provides the insights and reactions of one fiction writer who discovered that her works had been included on Great Britain's official reading list of the Revised Orders. Considers the rationale of the inclusion of the writer's own writing on the reading list. (HB)

  7. Defining Professionalism in Teacher Education Programs

    Science.gov (United States)

    Creasy, Kim L.

    2015-01-01

    Professionalism and how it is to be acquired should be a focus of every teacher education program. Despite the significant role professionalism plays there is a lack of a universally accepted definition of professionalism in teacher education programs. This paper investigates "working definitions" of professionalism as they pertain to…

  8. Defining stakeholder involvement in participatory design processes

    NARCIS (Netherlands)

    Vink, P.; Imada, A.S.; Zink, K.J.

    2008-01-01

    A participatory approach could be used to implement work place or organizational improvements. However, the question is which participants should be involved and how. In this paper the theoretical involvement in different steps of a linear stepwise approach is described and compared with the latest

  9. 20 CFR 725.491 - Operator defined.

    Science.gov (United States)

    2010-04-01

    ... coal mine dust as a result of such employment (see § 725.202); (ii) In accordance with the provisions... awarding benefits against a corporation that has not secured its liability for benefits in accordance with... shall not be contingent upon the amount or percentage of its work or business related to activities...

  10. 20 CFR 404.429 - Earnings; defined.

    Science.gov (United States)

    2010-04-01

    ... significant work activity you performed in the operation or management of a trade, profession, or business... countable for purposes of the earnings test until it is shown to our satisfaction that such income may be... employees in running the business for you; (D) Personally contacting an old and valued customer solely for...

  11. Software Defined Networking Demands on Software Technologies

    DEFF Research Database (Denmark)

    Galinac Grbac, T.; Caba, Cosmin Marius; Soler, José

    2015-01-01

    Software Defined Networking (SDN) is a networking approach based on a centralized control plane architecture with standardised interfaces between control and data planes. SDN enables fast configuration and reconfiguration of the network to enhance resource utilization and service performances....... This new approach enables a more dynamic and flexible network, which may adapt to user needs and application requirements. To this end, systemized solutions must be implemented in network software, aiming to provide secure network services that meet the required service performance levels. In this paper......, we review this new approach to networking from an architectural point of view, and identify and discuss some critical quality issues that require new developments in software technologies. These issues we discuss along with use case scenarios. Here in this paper we aim to identify challenges...

  12. Defining Service and Education in Pediatrics.

    Science.gov (United States)

    Boyer, Debra; Gagne, Josh; Kesselheim, Jennifer C

    2016-12-01

    Program directors (PDs) and trainees are often queried regarding the balance of service and education during pediatric residency training. We aimed to use qualitative methods to learn how pediatric residents and PDs define service and education and to identify activities that exemplify these concepts. Focus groups of pediatric residents and PDs were performed and the data qualitatively analyzed. Thematic analysis revealed 4 themes from focus group data: (1) misalignment of the perceived definition of service; (2) agreement about the definition of education; (3) overlapping perceptions of the value of service to training; and (4) additional suggestions for improved integration of education and service. Pediatric residents hold positive definitions of service and believe that service adds value to their education. Importantly, the discovery of heterogeneous definitions of service between pediatric residents and PDs warrants further investigation and may have ramifications for Accreditation Council for Graduate Medical Education and those responsible for residency curricula.

  13. Multiple Phenotypic Changes Define Neutrophil Priming

    Science.gov (United States)

    Miralda, Irina; Uriarte, Silvia M.; McLeish, Kenneth R.

    2017-01-01

    Exposure to pro-inflammatory cytokines, chemokines, mitochondrial contents, and bacterial and viral products induces neutrophils to transition from a basal state into a primed one, which is currently defined as an enhanced response to activating stimuli. Although, typically associated with enhanced generation of reactive oxygen species (ROS) by the NADPH oxidase, primed neutrophils show enhanced responsiveness of exocytosis, NET formation, and chemotaxis. Phenotypic changes associated with priming also include activation of a subset of functions, including adhesion, transcription, metabolism, and rate of apoptosis. This review summarizes the breadth of phenotypic changes associated with priming and reviews current knowledge of the molecular mechanisms behind those changes. We conclude that the current definition of priming is too restrictive. Priming represents a combination of enhanced responsiveness and activated functions that regulate both adaptive and innate immune responses. PMID:28611952

  14. Multiphoton microscopy in defining liver function

    Science.gov (United States)

    Thorling, Camilla A.; Crawford, Darrell; Burczynski, Frank J.; Liu, Xin; Liau, Ian; Roberts, Michael S.

    2014-09-01

    Multiphoton microscopy is the preferred method when in vivo deep-tissue imaging is required. This review presents the application of multiphoton microscopy in defining liver function. In particular, multiphoton microscopy is useful in imaging intracellular events, such as mitochondrial depolarization and cellular metabolism in terms of NAD(P)H changes with fluorescence lifetime imaging microscopy. The morphology of hepatocytes can be visualized without exogenously administered fluorescent dyes by utilizing their autofluorescence and second harmonic generation signal of collagen, which is useful in diagnosing liver disease. More specific imaging, such as studying drug transport in normal and diseased livers are achievable, but require exogenously administered fluorescent dyes. If these techniques can be translated into clinical use to assess liver function, it would greatly improve early diagnosis of organ viability, fibrosis, and cancer.

  15. Defining and measuring pilot mental workload

    Science.gov (United States)

    Kantowitz, Barry H.

    1988-01-01

    A theory is sought that is general enough to help the researcher deal with a wide range of situations involving pilot mental stress. A limited capacity theory of attention forms the basis for the theory. Mental workload is then defined as an intervening variable, similar to attention, that modulates or indexes the tuning between the demands of the environment and the capacity of the organism. Two methods for measuring pilot mental workload are endorsed: (1) objective measures based on secondary tasks; and (2) psychophysiological measures, which have not yet been perfected but which will become more useful as theoretical models are refined. Secondary-task research is illustrated by simulator studies in which flying performance has been shown not to be adversely affected by adding a complex choice-reaction secondary task.

  16. Quantum computing. Defining and detecting quantum speedup.

    Science.gov (United States)

    Rønnow, Troels F; Wang, Zhihui; Job, Joshua; Boixo, Sergio; Isakov, Sergei V; Wecker, David; Martinis, John M; Lidar, Daniel A; Troyer, Matthias

    2014-07-25

    The development of small-scale quantum devices raises the question of how to fairly assess and detect quantum speedup. Here, we show how to define and measure quantum speedup and how to avoid pitfalls that might mask or fake such a speedup. We illustrate our discussion with data from tests run on a D-Wave Two device with up to 503 qubits. By using random spin glass instances as a benchmark, we found no evidence of quantum speedup when the entire data set is considered and obtained inconclusive results when comparing subsets of instances on an instance-by-instance basis. Our results do not rule out the possibility of speedup for other classes of problems and illustrate the subtle nature of the quantum speedup question.

  17. Defining Starch Binding by Glucan Phosphatases

    DEFF Research Database (Denmark)

    Auger, Kyle; Raththagala, Madushi; Wilkens, Casper;

    2015-01-01

    Starch is a vital energy molecule in plants that has a wide variety of uses in industry, such as feedstock for biomaterial processing and biofuel production. Plants employ a three enzyme cyclic process utilizing kinases, amylases, and phosphatases to degrade starch in a diurnal manner. Starch...... is comprised of the branched glucan amylopectin and the more linear glucan amylose. Our lab has determined the first structures of these glucan phosphatases and we have defined their enzymatic action. Despite this progress, we lacked a means to quickly and efficiently quantify starch binding to glucan...... phosphatases. The main objective of this study was to quantify the binding affinity of different enzymes that are involved in this cyclic process. We established a protocol to quickly, reproducibly, and quantitatively measure the binding of the enzymes to glucans utilizing Affinity Gel Electrophoresis (AGE...

  18. Using archetypes for defining CDA templates.

    Science.gov (United States)

    Moner, David; Moreno, Alberto; Maldonado, José A; Robles, Montserrat; Parra, Carlos

    2012-01-01

    While HL7 CDA is a widely adopted standard for the documentation of clinical information, the archetype approach proposed by CEN/ISO 13606 and openEHR is gaining recognition as a means of describing domain models and medical knowledge. This paper describes our efforts in combining both standards. Using archetypes as an alternative for defining CDA templates permit new possibilities all based on the formal nature of archetypes and their ability to merge into the same artifact medical knowledge and technical requirements for semantic interoperability of electronic health records. We describe the process followed for the normalization of existing legacy data in a hospital environment, from the importation of the HL7 CDA model into an archetype editor, the definition of CDA archetypes and the application of those archetypes to obtain normalized CDA data instances.

  19. Oscillator metrology with software defined radio

    CERN Document Server

    Sherman, Jeff A

    2016-01-01

    Analog electrical elements such as mixers, filters, transfer oscillators, isolating buffers, dividers, and even transmission lines contribute technical noise and unwanted environmental coupling in time and frequency measurements. Software defined radio (SDR) techniques replace many of these analog components with digital signal processing (DSP) on rapidly sampled signals. We demonstrate that, generically, commercially available multi-channel SDRs are capable of time and frequency metrology, outperforming purpose-built devices by as much as an order-of-magnitude. For example, for signals at 10 MHz and 6 GHz, we observe SDR time deviation noise floors of about 20 fs and 1 fs, respectively, in under 10 ms of averaging. Examining the other complex signal component, we find a relative amplitude measurement instability of 3e-7 at 5 MHz. We discuss the scalability of a SDR-based system for simultaneous measurement of many clocks. SDR's frequency agility allows for comparison of oscillators at widely different freque...

  20. Can we define climate using information theory?

    Energy Technology Data Exchange (ETDEWEB)

    Larson, J Walter, E-mail: larson@mcs.anl.go [Mathematics and Computer Science Division, Argonne National Laboratory, Argonne, IL (United States); Computation Institute, University of Chicago, Chicago, IL (United States); School of Computer Science, The Australian National University, Canberra, ACT (Australia)

    2010-08-15

    The standard definition of climate is, by convention, based on a thirty-year sample. But why? One way to define the sampling period for constructing climatologies is to ask: What is a sufficient sample to construct probability density functions (PDF) for key meteorological variables? I propose an information-theoretic framework for evaluating climatic sampling periods based on level of detail and associated uncertainties in the estimated PDF, the Shannon entropy growth curve and its discrete derivative, and the Kullback-Leibler divergence. I compute these quantities for 235 years of daily data from the Central UK Temperature record and use these statistics to compare popular sampling periods and discuss the feasibility of determining an optimal sampling period.

  1. Defining and Distinguishing Secular and Religious Terrorism

    Directory of Open Access Journals (Sweden)

    Heather S. Gregg

    2014-04-01

    Full Text Available Religious terrorism is typically characterised as acts of unrestrained, irrational and indiscriminant violence, thus offering few if any policy options for counterterrorism measures. This assumption about religious terrorism stems from two challenges in the literature: disproportionate attention to apocalyptic terrorism, and a lack of distinction between religious terrorism and its secular counterpart. This article, therefore, aims to do four things: define and differentiate religiously motivated terrorism from traditional terrorism; investigate three goals of religious terrorism (fomenting the apocalypse, creating a religious government, and establishing a religiously pure state; consider the role of leadership and target selection of religious terrorists; and, finally, suggest a range of counterterrorism strategies based on these observations.

  2. Computing platforms for software-defined radio

    CERN Document Server

    Nurmi, Jari; Isoaho, Jouni; Garzia, Fabio

    2017-01-01

    This book addresses Software-Defined Radio (SDR) baseband processing from the computer architecture point of view, providing a detailed exploration of different computing platforms by classifying different approaches, highlighting the common features related to SDR requirements and by showing pros and cons of the proposed solutions. Coverage includes architectures exploiting parallelism by extending single-processor environment (such as VLIW, SIMD, TTA approaches), multi-core platforms distributing the computation to either a homogeneous array or a set of specialized heterogeneous processors, and architectures exploiting fine-grained, coarse-grained, or hybrid reconfigurability. Describes a computer engineering approach to SDR baseband processing hardware; Discusses implementation of numerous compute-intensive signal processing algorithms on single and multicore platforms; Enables deep understanding of optimization techniques related to power and energy consumption of multicore platforms using several basic a...

  3. Recognizing and defining clinical nurse leaders.

    Science.gov (United States)

    Stanley, David

    This article addresses the issue of clinical leadership and how it is defined. The concepts and definitions of clinical leadership are considered as well as the results of new research that suggests that clinical leaders can be seen as experts in their field, and because they are approachable and are effective communicators, are empowered to act as a role model, motivating others by matching their values and beliefs about nursing and care to their practice. This is supported by a new leadership theory, congruent leadership, proposed as the most appropriate leadership theory to support an understanding of clinical leadership. Congruent leaders (clinical nurse leaders) are followed because there is a match between the leader's values and beliefs and their actions.

  4. Defining nodes in complex brain networks

    Directory of Open Access Journals (Sweden)

    Matthew Lawrence Stanley

    2013-11-01

    Full Text Available Network science holds great promise for expanding our understanding of the human brain in health, disease, development, and aging. Network analyses are quickly becoming the method of choice for analyzing functional MRI data. However, many technical issues have yet to be confronted in order to optimize results. One particular issue that remains controversial in functional brain network analyses is the definition of a network node. In functional brain networks a node represents some predefined collection of brain tissue, and an edge measures the functional connectivity between pairs of nodes. The characteristics of a node, chosen by the researcher, vary considerably in the literature. This manuscript reviews the current state of the art based on published manuscripts and highlights the strengths and weaknesses of three main methods for defining nodes. Voxel-wise networks are constructed by assigning a node to each, equally sized brain area (voxel. The fMRI time-series recorded from each voxel is then used to create the functional network. Anatomical methods utilize atlases to define the nodes based on brain structure. The fMRI time-series from all voxels within the anatomical area are averaged and subsequently used to generate the network. Functional activation methods rely on data from traditional fMRI activation studies, often from databases, to identify network nodes. Such methods identify the peaks or centers of mass from activation maps to determine the location of the nodes. Small (~10-20 millimeter diameter spheres located at the coordinates of the activation foci are then applied to the data being used in the network analysis. The fMRI time-series from all voxels in the sphere are then averaged, and the resultant time series is used to generate the network. We attempt to clarify the discussion and move the study of complex brain networks forward. While the correct method to be used remains an open, possibly unsolvable question that

  5. Volume Renormalization and the Higgs

    CERN Document Server

    Dai, De-Chang

    2014-01-01

    Traditionally, Quantum Field Theory (QFT) treats particle excitations as point-like objects, which is the source of ubiquitous divergences. We demonstrate that a minimal modification of QFT with finite volume particles may cure QFT of divergences and illuminate the physics behind the mathematical construct of our theories. The method allows for a non-perturbative treatment of the free field and self-interacting theories (though extensions to all interacting field theories might be possible). In particular, non-perturbatively defined mass is finite. When applied to the standard model Higgs mechanism, the method implies that a finite range of parameters allows for creation of a well defined Higgs particle, whose Compton wavelength is larger than its physical size, in the broken symmetry phase (as small oscillations around the vacuum). This has profound consequences for Higgs production at the LHC. The parameter range in which the Higgs excitation with the mass of 125 GeV behaves as a proper particle is very res...

  6. Site Environmental Report for 2005 Volume I and Volume II

    Energy Technology Data Exchange (ETDEWEB)

    Ruggieri, Michael

    2006-07-07

    Each year, Ernest Orlando Lawrence Berkeley National Laboratory prepares an integrated report on its environmental programs to satisfy the requirements of United States Department of Energy Order 231.1A, ''Environment, Safety, and Health Reporting''. The ''Site Environmental Report for 2005'' summarizes Berkeley Lab's environmental management performance, presents environmental monitoring results, and describes significant programs for calendar year 2005. (Throughout this report, Ernest Orlando Lawrence Berkeley National Laboratory is referred to as ''Berkeley Lab'', ''the Laboratory'', ''Lawrence Berkeley National Laboratory'', and ''LBNL''.) The report is separated into two volumes. Volume I contains an overview of the Laboratory, the status of environmental programs, and summarized results from surveillance and monitoring activities. This year's Volume I text body is organized into an executive summary followed by six chapters. The report's structure has been reorganized this year, and it now includes a chapter devoted to environmental management system topics. Volume II contains individual data results from surveillance and monitoring activities. The ''Site Environmental Report'' is distributed by releasing it on the Web from the Berkeley Lab Environmental Services Group (ESG) home page, which is located at http://www.lbl.gov/ehs/esg/. Many of the documents cited in this report also are accessible from the ESG Web page. CD and printed copies of this Site Environmental Report are available upon request. The report follows the Laboratory's policy of using the International System of Units (SI), also known as the metric system of measurements. Whenever possible, results are also reported using the more conventional (non-SI) system of measurements, because the non-SI system is referenced by several current

  7. RESUMING WORK

    CERN Multimedia

    2003-01-01

    In application of the Staff Rules and Regulations, every member of the CERN personnel is required to undergo a medical examination on resuming work after sick leave: - if the medical absence has been for 21 calendar days or longer - if absent more than 48 hours due to professional accident It is incumbent upon the member of the personnel himself/herself to contact the Medical Service Tel. 73186, without awaiting its summons. The purpose of this exam is not to check on the absenteeism, but to support the professional reinsertion. Medical Service

  8. RESUMING WORK

    CERN Multimedia

    2003-01-01

    In application of the Staff Rules and Regulations, every member of the CERN personnel is required to undergo a medical examination on resuming work after sick leave: - if the medical absence has been for 21 calendar days or longer - if absent more than 48 hours due to professional accident It is incumbent upon the member of the personnel himself/herself to contact the Medical Service tel. 73186, without awaiting its summons. The purpose of this exam is not to check on the absenteeism, but to support the professional reinsertion. Medical Service

  9. RESUMING WORK

    CERN Multimedia

    2004-01-01

    In application of the Staff Rules and Regulations, every member of the CERN personnel is required to undergo a medical examination on resuming work after sick leave: • if the medical absence has been for 21 calendar days or longer • if absent more than 48 hours due to professional accident It is incumbent upon the member of the personnel himself/herself to contact the Medical Service tel. 73186, without awaiting its summons. The purpose of this exam is not to check on the absenteeism, but to support the professional reinsertion. Medical Service

  10. Free volume under shear

    Science.gov (United States)

    Maiti, Moumita; Vinutha, H. A.; Sastry, Srikanth; Heussinger, Claus

    2015-10-01

    Using an athermal quasistatic simulation protocol, we study the distribution of free volumes in sheared hard-particle packings close to, but below, the random-close packing threshold. We show that under shear, and independent of volume fraction, the free volumes develop features similar to close-packed systems — particles self-organize in a manner as to mimick the isotropically jammed state. We compare athermally sheared packings with thermalized packings and show that thermalization leads to an erasure of these structural features. The temporal evolution in particular the opening-up and the closing of free-volume patches is associated with the single-particle dynamics, showing a crossover from ballistic to diffusive behavior.

  11. Renormalized Volumes with Boundary

    CERN Document Server

    Gover, A Rod

    2016-01-01

    We develop a general regulated volume expansion for the volume of a manifold with boundary whose measure is suitably singular along a separating hypersurface. The expansion is shown to have a regulator independent anomaly term and a renormalized volume term given by the primitive of an associated anomaly operator. These results apply to a wide range of structures. We detail applications in the setting of measures derived from a conformally singular metric. In particular, we show that the anomaly generates invariant (Q-curvature, transgression)-type pairs for hypersurfaces with boundary. For the special case of anomalies coming from the volume enclosed by a minimal hypersurface ending on the boundary of a Poincare--Einstein structure, this result recovers Branson's Q-curvature and corresponding transgression. When the singular metric solves a boundary version of the constant scalar curvature Yamabe problem, the anomaly gives generalized Willmore energy functionals for hypersurfaces with boundary. Our approach ...

  12. Environmental chemistry: Volume A

    Energy Technology Data Exchange (ETDEWEB)

    Yen, T.F.

    1999-08-01

    This is an extensive introduction to environmental chemistry for engineering and chemical professionals. The contents of Volume A include a brief review of basic chemistry prior to coverage of litho, atmo, hydro, pedo, and biospheres.

  13. Evaluation of an Empirical Reservoir Shape Function to Define Sediment Distributions in Small Reservoirs

    OpenAIRE

    Bogusław Michalec

    2015-01-01

    Understanding and defining the spatial distribution of sediment deposited in reservoirs is essential not only at the design stage but also during the operation. The majority of research concerns the distribution of sediment deposition in medium and large water reservoirs. Most empirical methods do not provide satisfactory results when applied to the determination of sediment deposition in small reservoirs. Small reservoir’s volumes do not exceed 5 × 106 m3 and their capacity-inflow ratio is l...

  14. Decent Work: A Psychological Perspective

    Science.gov (United States)

    Blustein, David L.; Olle, Chad; Connors-Kellgren, Alice; Diamonti, A. J.

    2016-01-01

    This contribution, which serves as the lead article for the Research Topic entitled “From Meaning of Working to Meaningful Lives: The Challenges of Expanding Decent Work,” explores current challenges in the development and operationalization of decent work. Based on an initiative from the International Labor Organization [ILO] (1999) decent work represents an aspirational statement about the quality of work that should be available to all people who seek to work around the globe. Within recent years, several critiques have been raised about decent work from various disciplines, highlighting concerns about a retreat from the social justice ethos that had initially defined the concept. In addition, other scholars have observed that decent work has not included a focus on the role of meaning and purpose at work. To address these concerns, we propose that a psychological perspective can help to revitalize the decent work agenda by infusing a more specific focus on individual experiences and by reconnecting decent work to its social justice origins. As an illustration of the advantages of a psychological perspective, we explore the rise of precarious work and also connect the decent work agenda to the Psychology-of-Working Framework and Theory (Blustein, 2006; Duffy et al., 2016). PMID:27047430

  15. Decent Work: A Psychological Perspective

    Directory of Open Access Journals (Sweden)

    David eBlustein

    2016-03-01

    Full Text Available This contribution, which serves as the lead article for the Research Section entitled From Meaning of Working to Meaningful Lives: The Challenges of Expanding Decent Work, explores current challenges in the development and operationalization of decent work. Based on an initiative from the International Labor Organization (ILO; 1999, decent work represents an aspirational statement about the quality of work that should be available to all people who seek to work around the globe. Within recent years, several critiques have been raised about decent work from various disciplines, highlighting concerns about a retreat from the social justice ethos that had initially defined the concept. In addition, other scholars have observed that decent work has not included a focus on the role of meaning and purpose at work. To address these concerns, we propose that a psychological perspective can help to revitalize the decent work agenda by infusing a more specific focus on individual experiences and by reconnecting decent work to its social justice origins. As an illustration of the advantages of a psychological perspective, we explore the rise of precarious work and also connect the decent work agenda to the Psychology-of-Working Framework and Theory (Blustein, 2006; Duffy, Blustein, Diemer, and Autin, in press.

  16. Generalized Partial Volume

    DEFF Research Database (Denmark)

    Darkner, Sune; Sporring, Jon

    2011-01-01

    Mutual Information (MI) and normalized mutual information (NMI) are popular choices as similarity measure for multimodal image registration. Presently, one of two approaches is often used for estimating these measures: The Parzen Window (PW) and the Generalized Partial Volume (GPV). Their theoret......Mutual Information (MI) and normalized mutual information (NMI) are popular choices as similarity measure for multimodal image registration. Presently, one of two approaches is often used for estimating these measures: The Parzen Window (PW) and the Generalized Partial Volume (GPV...

  17. Harassment in the workplace - defining the boundaries

    CERN Multimedia

    2002-01-01

    Around 300 people attended the talk on 'Sexual and psychological harassment: suffering at work' given by specialist Véronique Ducret at CERN at the end of May. The Equal Opportunities Advisory Panel organised this event with the aim of making it clear to CERN personnel what sexual harassment and mobbing are, and how to combat them.   Véronique Ducret during her talk at CERN. A look can have a thousand different connotations. But at what point does it stop being just a look and become an intrusion on someone's privacy? When someone persists in this kind of behaviour, it ends up by making the other person feel uncomfortable. This was one of the questions that was answered during Véronique Ducret's talk on 'Sexual and psychological harassment: suffering at work'. Another question answered concerned mobbing - up to what point is it acceptable to put pressure on someone at work? Here again her answer pointed to situations which persist over time and the manner in which the pressure is applied. These kinds o...

  18. Reachable volume RRT

    KAUST Repository

    McMahon, Troy

    2015-05-01

    © 2015 IEEE. Reachable volumes are a new technique that allows one to efficiently restrict sampling to feasible/reachable regions of the planning space even for high degree of freedom and highly constrained problems. However, they have so far only been applied to graph-based sampling-based planners. In this paper we develop the methodology to apply reachable volumes to tree-based planners such as Rapidly-Exploring Random Trees (RRTs). In particular, we propose a reachable volume RRT called RVRRT that can solve high degree of freedom problems and problems with constraints. To do so, we develop a reachable volume stepping function, a reachable volume expand function, and a distance metric based on these operations. We also present a reachable volume local planner to ensure that local paths satisfy constraints for methods such as PRMs. We show experimentally that RVRRTs can solve constrained problems with as many as 64 degrees of freedom and unconstrained problems with as many as 134 degrees of freedom. RVRRTs can solve problems more efficiently than existing methods, requiring fewer nodes and collision detection calls. We also show that it is capable of solving difficult problems that existing methods cannot.

  19. Self-defining memories and self-defining future projections in hypomania-prone individuals.

    Science.gov (United States)

    Lardi Robyn, Claudia; Ghisletta, Paolo; Van der Linden, Martial

    2012-06-01

    Mania and hypomania involve dysfunctional beliefs about the self, others, and the world, as well about affect regulation. The present study explored the impact of these beliefs on self-defining memories and self-defining future projections of individuals with a history of hypomanic symptoms. The main findings showed that a history of hypomanic symptoms was related to enhanced retrieval of memories describing positive relationships and to reduced future projections about relationships, suggesting both a need for social bonding and a striving for autonomy. Moreover, hypomania-prone individuals tended to describe more recent events and to produce self-defining memories with references to tension that were more integrated in their self-structure. All of these findings support the presence of conflicting dysfunctional beliefs and the importance of memories containing references to tension in hypomania.

  20. Defining nodes in complex brain networks.

    Science.gov (United States)

    Stanley, Matthew L; Moussa, Malaak N; Paolini, Brielle M; Lyday, Robert G; Burdette, Jonathan H; Laurienti, Paul J

    2013-11-22

    Network science holds great promise for expanding our understanding of the human brain in health, disease, development, and aging. Network analyses are quickly becoming the method of choice for analyzing functional MRI data. However, many technical issues have yet to be confronted in order to optimize results. One particular issue that remains controversial in functional brain network analyses is the definition of a network node. In functional brain networks a node represents some predefined collection of brain tissue, and an edge measures the functional connectivity between pairs of nodes. The characteristics of a node, chosen by the researcher, vary considerably in the literature. This manuscript reviews the current state of the art based on published manuscripts and highlights the strengths and weaknesses of three main methods for defining nodes. Voxel-wise networks are constructed by assigning a node to each, equally sized brain area (voxel). The fMRI time-series recorded from each voxel is then used to create the functional network. Anatomical methods utilize atlases to define the nodes based on brain structure. The fMRI time-series from all voxels within the anatomical area are averaged and subsequently used to generate the network. Functional activation methods rely on data from traditional fMRI activation studies, often from databases, to identify network nodes. Such methods identify the peaks or centers of mass from activation maps to determine the location of the nodes. Small (~10-20 millimeter diameter) spheres located at the coordinates of the activation foci are then applied to the data being used in the network analysis. The fMRI time-series from all voxels in the sphere are then averaged, and the resultant time series is used to generate the network. We attempt to clarify the discussion and move the study of complex brain networks forward. While the "correct" method to be used remains an open, possibly unsolvable question that deserves extensive

  1. Hippocampal Atrophy Varies by Neuropsychologically-Defined MCI among Men in Their 50s

    Science.gov (United States)

    Jak, Amy J.; Panizzon, Matthew S.; Spoon, Kelly M.; Fennema-Notestine, Christine; Franz, Carol E.; Thompson, Wesley, K.; Jacobson, Kristen C.; Xian, Hong; Eyler, Lisa T.; Vuoksimaa, Eero; Toomey, Rosemary; Lyons, Michael J.; Neale, Michael C.; Tsuang, Ming T.; Dale, Anders M.; Kremen, William S.

    2014-01-01

    Objective In an effort to address earliest detection of Mild Cognitive Impairment (MCI), we examined hippocampal volumes and atrophy in middle-aged males to explore neuroanatomical support for different neuropsychological definitions of MCI. Methods 460 men ages 51-60 underwent neuropsychological testing and an MRI. MCI was defined according to five criteria sets. MRI-derived hippocampal volume and hippocampal occupancy (HOC) were obtained via FreeSurfer. Statistical analyses were performed using linear mixed models. Results Differences in HOC between normal cognitive functioning, amnestic, and non-amnestic MCI were observed using MCI criteria that required one impaired (>1.5 SD) cognitive measure in a given cognitive domain or a cognitive composite score method with a cut-point 2 SD below the mean. Differences in standard hippocampal volume were only found between normal and amnestic presentations and only when using the composite score method. Conclusions Results provide empirical support for detection of pre-MCI in younger cohorts. Convergence of neuropsychological and neuroanatomical data, particularly HOC (as opposed to standard cross-sectional volume), supports early identification of MCI as defined by some neuropsychological criteria. PMID:25306196

  2. Papers, Volume 2 1986-1989

    DEFF Research Database (Denmark)

    Thoft-Christensen, Palle

    In this Volume 2 of “Papers”, 20 papers published in 1986 - 1989 are presented. The papers are reproduced by using scanning techniques and retyping of equations. During this work, small modifications and corrections have been made. Unfortunately, new errors may have been introduced. This is my...

  3. Papers, Volume 1 1962-1985

    DEFF Research Database (Denmark)

    Thoft-Christensen, Palle

    In this Volume 1 of “Papers”, 20 papers published from 1962 to 1985 are presented. The papers are reproduced by using scanning techniques and retyping of equations. During this work, small modifications and corrections have been made. Unfortunately, new errors may have been introduced. This is my...

  4. Papers, Volume 1 1962-1985

    DEFF Research Database (Denmark)

    Thoft-Christensen, Palle

    In this Volume 1 of “Papers”, 20 papers published from 1962 to 1985 are presented. The papers are reproduced by using scanning techniques and retyping of equations. During this work, small modifications and corrections have been made. Unfortunately, new errors may have been introduced. This is my...

  5. Papers, Volume 2 1986-1989

    DEFF Research Database (Denmark)

    Thoft-Christensen, Palle

    In this Volume 2 of “Papers”, 20 papers published in 1986 - 1989 are presented. The papers are reproduced by using scanning techniques and retyping of equations. During this work, small modifications and corrections have been made. Unfortunately, new errors may have been introduced. This is my re...

  6. Architecturally defined scaffolds from synthetic collagen and elastin analogues for the fabrication of bioengineered tissues

    Science.gov (United States)

    Caves, Jeffrey Morris

    The microstructure and mechanics of collagen and elastin protein fiber networks dictate the mechanical responses of all soft tissues and related organ systems. In this project, we endeavored to meet or exceed native tissue biomechanical properties through mimicry of these extracellular matrix components with synthetic collagen fiber and a recombinant elastin-like protein polymer. Significantly, this work led to the development of a framework for the design and fabrication of protein-based tissue substitutes with enhanced strength, resilience, anisotropy, and more. We began with the development of a spinning process for scalable production of synthetic collagen fiber. Fiber with an elliptical cross-section of 53 +/- 14 by 21 +/- 3 mum and an ultimate tensile strength of 90 +/- 19 MPa was continuously produced at 60 meters per hour from an ultrafiltered collagen solution. The starting collagen concentration, flowrate, and needle size could be adjusted to control fiber size. The fiber was characterized with mechanical analysis, micro-differential scanning calorimetry, transmission electron microscopy, second harmonic generation analysis, and subcutaneous murine implant. We subsequently describe the scalable, semi-automated fabrication of elastin-like protein sheets reinforced with synthetic collagen fibers that can be positioned in a precisely defined three-dimensional hierarchical pattern. Multilamellar, fiber-reinforced elastic protein sheets were constructed with controlled fiber orientation and volume fraction. Structures were analyzed with scanning electron microscopy, transmission electron microscopy, and digital volumetric imaging. The effect of fiber orientation and volume fraction on Young's Modulus, yield stress, ultimate tensile stress, strain-to-failure, and resilience was evaluated in uniaxial tension. Increased fiber volume fraction and alignment with applied deformation significantly increased Young's Modulus, resilience, and yield stress. Highly

  7. Defining microbiota for developing new probiotics

    Directory of Open Access Journals (Sweden)

    Maria Carmen Collado

    2012-06-01

    Full Text Available The human body harbors complex communities of microbes that play a prominent role in human health. Detailed characterization of the microbiota in the target population forms the basis of probiotic use. Probiotics are defined as live bacterial preparations with clinically documented health effects in humans, and independent of their genus and species, probiotic strains are unique and their beneficial properties on human health have to be assessed in a case-by-case manner. Understanding the mechanisms by which probiotics influence microbiota would facilitate the use of probiotics for both dietary management and reduction in risk of specific diseases. The development of high throughput sequencing methods has allowed metagenomic approaches to study the human microbiome. These efforts are starting to generate an inventory of bacterial taxons and functional features bound to particular health or disease status that allow inferring aspects of the microbiome's function. In the future, this information will allow the rational design of dietary interventions aimed to improve consumer's health via modulation of the microbiota.

  8. Defining Astrology in Ancient and Classical History

    Science.gov (United States)

    Campion, Nicholas

    2015-05-01

    Astrology in the ancient and classical worlds can be partly defined by its role, and partly by the way in which scholars spoke about it. The problem is complicated by the fact that the word is Greek - it has no Babylonian or Egyptian cognates - and even in Greece it was interchangeable with its cousin, 'astronomy'. Yet if we are to understand the role of the sky, stars and planets in culture, debates about the nature of ancient astrology, by both classical and modern scholars, must be taken into account. This talk will consider modern scholars' typologies of ancient astrology, together with ancient debates from Cicero in the 1st century BC, to Plotinus (204/5-270 AD) and Isidore of Seville (c. 560 - 4 April 636). It will consider the implications for our understanding of astronomy's role in culture, and conclude that in the classical period astrology may be best understood through its diversity and allegiance to competing philosophies, and that its functions were therefore similarly varied.

  9. Like Beauty, Complexity is Hard to Define

    Science.gov (United States)

    Tsallis, Constantino

    Like beauty, complexity is hard to define and rather easy to identify: nonlinear dynamics, strongly interconnected simple elements, some sort of divisoria aquorum between order and disorder. Before focusing on complexity, let us remember that the theoretical pillars of contemporary physics are mechanics (Newtonian, relativistic, quantum), Maxwell electromagnetism, and (Boltzmann-Gibbs, BG) statistical mechanics - obligatory basic disciplines in any advanced course in physics. The firstprinciple statistical-mechanical approach starts from (microscopic) electro-mechanics and theory of probabilities, and, through a variety of possible mesoscopic descriptions, arrives to (oscopic) thermodynamics. In the middle of this trip, we cross energy and entropy. Energy is related to the possible microscopic configurations of the system, whereas entropy is related to the corresponding probabilities. Therefore, in some sense, entropy represents a concept which, epistemologically speaking, is one step further with regard to energy. The fact that energy is not parameter-independent is very familiar: the kinetic energy of a truck is very different from that of a fly, and the relativistic energy of a fast electron is very different from its classical value, and so on. What about entropy? One hundred and forty years of tradition, and hundreds - we may even say thousands - of impressive theoretical successes of the parameter-free BG entropy have sedimented, in the mind of many scientists, the conviction that it is unique. However, it can be straightforwardly argued that, in general, this is not the case...

  10. Software-defined Quantum Networking Ecosystem

    Energy Technology Data Exchange (ETDEWEB)

    2017-01-01

    The software enables a user to perform modeling and simulation of software-defined quantum networks. The software addresses the problem of how to synchronize transmission of quantum and classical signals through multi-node networks and to demonstrate quantum information protocols such as quantum teleportation. The software approaches this problem by generating a graphical model of the underlying network and attributing properties to each node and link in the graph. The graphical model is then simulated using a combination of discrete-event simulators to calculate the expected state of each node and link in the graph at a future time. A user interacts with the software by providing an initial network model and instantiating methods for the nodes to transmit information with each other. This includes writing application scripts in python that make use of the software library interfaces. A user then initiates the application scripts, which invokes the software simulation. The user then uses the built-in diagnostic tools to query the state of the simulation and to collect statistics on synchronization.

  11. Methodologies for defining quality of life

    Energy Technology Data Exchange (ETDEWEB)

    Glicken, J. [Ecological Planning and Toxicology, Inc., Albuquerque, NM (United States); Engi, D. [Sandia National Labs., Albuquerque, NM (United States)

    1996-10-10

    Quality of life as a concept has been used in many ways in the public policy arena. It can be used in summative evaluations to assess the impacts of policies or programs. Alternatively, it can be applied to formative evaluations to provide input to the formation of new policies. In short, it provides the context for the understanding needed to evaluate the results of choices that have been made in the public policy arena, or the potential of choices yet to be made. In either case, the public policy question revolves around the positive or negative impact the choice will have on quality of life, and the magnitude of that impact. This discussion will develop a conceptual framework that proposes that an assessment of quality of life is based on a comparison of expectations with experience. The framework defines four basic components from which these expectations arise: natural conditions, social conditions, the body, and the mind. Each one of these components is generally described, and associated with a general policy or rhetorical category which gives it its policy vocabulary--environmental quality, economic well-being, human health, and self-fulfillment.

  12. Defining fitness in an uncertain world.

    Science.gov (United States)

    Crewe, Paul; Gratwick, Richard; Grafen, Alan

    2017-07-29

    The recently elucidated definition of fitness employed by Fisher in his fundamental theorem of natural selection is combined with reproductive values as appropriately defined in the context of both random environments and continuing fluctuations in the distribution over classes in a class-structured population. We obtain astonishingly simple results, generalisations of the Price Equation and the fundamental theorem, that show natural selection acting only through the arithmetic expectation of fitness over all uncertainties, in contrast to previous studies with fluctuating demography, in which natural selection looks rather complicated. Furthermore, our setting permits each class to have its characteristic ploidy, thus covering haploidy, diploidy and haplodiploidy at the same time; and allows arbitrary classes, including continuous variables such as condition. The simplicity is achieved by focussing just on the effects of natural selection on genotype frequencies: while other causes are present in the model, and the effect of natural selection is assessed in their presence, these causes will have their own further effects on genoytpe frequencies that are not assessed here. Also, Fisher's uses of reproductive value are shown to have two ambivalences, and a new axiomatic foundation for reproductive value is endorsed. The results continue the formal darwinism project, and extend support for the individual-as-maximising-agent analogy to finite populations with random environments and fluctuating class-distributions. The model may also lead to improved ways to measure fitness in real populations.

  13. Defining microbiota for developing new probiotics

    Science.gov (United States)

    Collado, Maria Carmen; Bäuerl, Christine; Pérez-Martínez, Gaspar

    2012-01-01

    The human body harbors complex communities of microbes that play a prominent role in human health. Detailed characterization of the microbiota in the target population forms the basis of probiotic use. Probiotics are defined as live bacterial preparations with clinically documented health effects in humans, and independent of their genus and species, probiotic strains are unique and their beneficial properties on human health have to be assessed in a case-by-case manner. Understanding the mechanisms by which probiotics influence microbiota would facilitate the use of probiotics for both dietary management and reduction in risk of specific diseases. The development of high throughput sequencing methods has allowed metagenomic approaches to study the human microbiome. These efforts are starting to generate an inventory of bacterial taxons and functional features bound to particular health or disease status that allow inferring aspects of the microbiome's function. In the future, this information will allow the rational design of dietary interventions aimed to improve consumer's health via modulation of the microbiota. PMID:23990820

  14. Defining microbiota for developing new probiotics.

    Science.gov (United States)

    Collado, Maria Carmen; Bäuerl, Christine; Pérez-Martínez, Gaspar

    2012-01-01

    The human body harbors complex communities of microbes that play a prominent role in human health. Detailed characterization of the microbiota in the target population forms the basis of probiotic use. Probiotics are defined as live bacterial preparations with clinically documented health effects in humans, and independent of their genus and species, probiotic strains are unique and their beneficial properties on human health have to be assessed in a case-by-case manner. Understanding the mechanisms by which probiotics influence microbiota would facilitate the use of probiotics for both dietary management and reduction in risk of specific diseases. The development of high throughput sequencing methods has allowed metagenomic approaches to study the human microbiome. These efforts are starting to generate an inventory of bacterial taxons and functional features bound to particular health or disease status that allow inferring aspects of the microbiome's function. In the future, this information will allow the rational design of dietary interventions aimed to improve consumer's health via modulation of the microbiota.

  15. Defining and resolving current systems in geospace

    Science.gov (United States)

    Ganushkina, N. Y.; Liemohn, M. W.; Dubyagin, S.; Daglis, I. A.; Dandouras, I.; De Zeeuw, D. L.; Ebihara, Y.; Ilie, R.; Katus, R.; Kubyshkina, M.; Milan, S. E.; Ohtani, S.; Ostgaard, N.; Reistad, J. P.; Tenfjord, P.; Toffoletto, F.; Zaharia, S.; Amariutei, O.

    2015-11-01

    Electric currents flowing through near-Earth space (R ≤ 12 RE) can support a highly distorted magnetic field topology, changing particle drift paths and therefore having a nonlinear feedback on the currents themselves. A number of current systems exist in the magnetosphere, most commonly defined as (1) the dayside magnetopause Chapman-Ferraro currents, (2) the Birkeland field-aligned currents with high-latitude "region 1" and lower-latitude "region 2" currents connected to the partial ring current, (3) the magnetotail currents, and (4) the symmetric ring current. In the near-Earth nightside region, however, several of these current systems flow in close proximity to each other. Moreover, the existence of other temporal current systems, such as the substorm current wedge or "banana" current, has been reported. It is very difficult to identify a local measurement as belonging to a specific system. Such identification is important, however, because how the current closes and how these loops change in space and time governs the magnetic topology of the magnetosphere and therefore controls the physical processes of geospace. Furthermore, many methods exist for identifying the regions of near-Earth space carrying each type of current. This study presents a robust collection of these definitions of current systems in geospace, particularly in the near-Earth nightside magnetosphere, as viewed from a variety of observational and computational analysis techniques. The influence of definitional choice on the resulting interpretation of physical processes governing geospace dynamics is presented and discussed.

  16. Defining Ecosystem Assets for Natural Capital Accounting.

    Science.gov (United States)

    Hein, Lars; Bagstad, Ken; Edens, Bram; Obst, Carl; de Jong, Rixt; Lesschen, Jan Peter

    2016-01-01

    In natural capital accounting, ecosystems are assets that provide ecosystem services to people. Assets can be measured using both physical and monetary units. In the international System of Environmental-Economic Accounting, ecosystem assets are generally valued on the basis of the net present value of the expected flow of ecosystem services. In this paper we argue that several additional conceptualisations of ecosystem assets are needed to understand ecosystems as assets, in support of ecosystem assessments, ecosystem accounting and ecosystem management. In particular, we define ecosystems' capacity and capability to supply ecosystem services, as well as the potential supply of ecosystem services. Capacity relates to sustainable use levels of multiple ecosystem services, capability involves prioritising the use of one ecosystem service over a basket of services, and potential supply considers the ability of ecosystems to generate services regardless of demand for these services. We ground our definitions in the ecosystem services and accounting literature, and illustrate and compare the concepts of flow, capacity, capability, and potential supply with a range of conceptual and real-world examples drawn from case studies in Europe and North America. Our paper contributes to the development of measurement frameworks for natural capital to support environmental accounting and other assessment frameworks.

  17. Defining a Standard Metric for Electricity Savings

    Energy Technology Data Exchange (ETDEWEB)

    Brown, Marilyn; Akbari, Hashem; Blumstein, Carl; Koomey, Jonathan; Brown, Richard; Calwell, Chris; Carter, Sheryl; Cavanagh, Ralph; Chang, Audrey; Claridge, David; Craig, Paul; Diamond, Rick; Eto, Joseph H.; Fulkerson, William; Gadgil, Ashok; Geller, Howard; Goldemberg, Jose; Goldman, Chuck; Goldstein, David B.; Greenberg, Steve; Hafemeister, David; Harris, Jeff; Harvey, Hal; Heitz, Eric; Hirst, Eric; Hummel, Holmes; Kammen, Dan; Kelly, Henry; Laitner, Skip; Levine, Mark; Lovins, Amory; Masters, Gil; McMahon, James E.; Meier, Alan; Messenger, Michael; Millhone, John; Mills, Evan; Nadel, Steve; Nordman, Bruce; Price, Lynn; Romm, Joe; Ross, Marc; Rufo, Michael; Sathaye, Jayant; Schipper, Lee; Schneider, Stephen H; Sweeney, James L; Verdict, Malcolm; Vorsatz, Diana; Wang, Devra; Weinberg, Carl; Wilk, Richard; Wilson, John; Worrell, Ernst

    2009-03-01

    The growing investment by governments and electric utilities in energy efficiency programs highlights the need for simple tools to help assess and explain the size of the potential resource. One technique that is commonly used in this effort is to characterize electricity savings in terms of avoided power plants, because it is easier for people to visualize a power plant than it is to understand an abstraction such as billions of kilowatt-hours. Unfortunately, there is no standardization around the characteristics of such power plants. In this letter we define parameters for a standard avoided power plant that have physical meaning and intuitive plausibility, for use in back-of-the-envelope calculations. For the prototypical plant this article settles on a 500 MW existing coal plant operating at a 70percent capacity factor with 7percent T&D losses. Displacing such a plant for one year would save 3 billion kW h per year at the meter and reduce emissions by 3 million metric tons of CO2 per year. The proposed name for this metric is the Rosenfeld, in keeping with the tradition among scientists of naming units in honor of the person most responsible for the discovery and widespread adoption of the underlying scientific principle in question--Dr. Arthur H. Rosenfeld.

  18. Oscillator metrology with software defined radio.

    Science.gov (United States)

    Sherman, Jeff A; Jördens, Robert

    2016-05-01

    Analog electrical elements such as mixers, filters, transfer oscillators, isolating buffers, dividers, and even transmission lines contribute technical noise and unwanted environmental coupling in time and frequency measurements. Software defined radio (SDR) techniques replace many of these analog components with digital signal processing (DSP) on rapidly sampled signals. We demonstrate that, generically, commercially available multi-channel SDRs are capable of time and frequency metrology, outperforming purpose-built devices by as much as an order-of-magnitude. For example, for signals at 10 MHz and 6 GHz, we observe SDR time deviation noise floors of about 20 fs and 1 fs, respectively, in under 10 ms of averaging. Examining the other complex signal component, we find a relative amplitude measurement instability of 3 × 10(-7) at 5 MHz. We discuss the scalability of a SDR-based system for simultaneous measurement of many clocks. SDR's frequency agility allows for comparison of oscillators at widely different frequencies. We demonstrate a novel and extreme example with optical clock frequencies differing by many terahertz: using a femtosecond-laser frequency comb and SDR, we show femtosecond-level time comparisons of ultra-stable lasers with zero measurement dead-time.

  19. Defining the bacteroides ribosomal binding site.

    Science.gov (United States)

    Wegmann, Udo; Horn, Nikki; Carding, Simon R

    2013-03-01

    The human gastrointestinal tract, in particular the colon, hosts a vast number of commensal microorganisms. Representatives of the genus Bacteroides are among the most abundant bacterial species in the human colon. Bacteroidetes diverged from the common line of eubacterial descent before other eubacterial groups. As a result, they employ unique transcription initiation signals and, because of this uniqueness, they require specific genetic tools. Although some tools exist, they are not optimal for studying the roles and functions of these bacteria in the human gastrointestinal tract. Focusing on translation initiation signals in Bacteroides, we created a series of expression vectors allowing for different levels of protein expression in this genus, and we describe the use of pepI from Lactobacillus delbrueckii subsp. lactis as a novel reporter gene for Bacteroides. Furthermore, we report the identification of the 3' end of the 16S rRNA of Bacteroides ovatus and analyze in detail its ribosomal binding site, thus defining a core region necessary for efficient translation, which we have incorporated into the design of our expression vectors. Based on the sequence logo information from the 5' untranslated region of other Bacteroidales ribosomal protein genes, we conclude that our findings are relevant to all members of this order.

  20. Defining functional dyspepsia Definiendo la dispepsia funcional

    Directory of Open Access Journals (Sweden)

    Fermín Mearin

    2011-12-01

    Full Text Available Dyspepsia and functional dyspepsia represent a highly significant public health issue. A good definition of dyspepsia is key for helping us to better approach symptoms, decision making, and therapy indications. During the last few years many attempts were made at establishing a definition of dyspepsia. Results were little successful on most occasions, and clear discrepancies arose on whether symptoms should be associated with digestion, which types of symptoms were to be included, which anatomic location should symptoms have, etc. The Rome III Committee defined dyspepsia as "a symptom or set of symptoms that most physicians consider to originate from the gastroduodenal area", including the following: postprandial heaviness, early satiety, and epigastric pain or burning. Two new entities were defined: a food-induced dyspeptic symptoms (postprandial distress syndrome; and b epigastric pain (epigastric pain syndrome. These and other definitions have shown both strengths and weaknesses. At times they have been much too complex, at times much too simple; furthermore, they have commonly erred on the side of being inaccurate and impractical. On the other hand, some (the most recent ones are difficult to translate into the Spanish language. In a meeting of gastroenterologists with a special interest in digestive functional disorders, the various aspects of dyspepsia definition were discussed and put to the vote, and the following conclusions were arrived at: dyspepsia is defined as a set of symptoms, either related or unrelated to food ingestion, localized on the upper half of the abdomen. They include: a epigastric discomfort (as a category of severity or pain; b postprandial heaviness; and c early satiety. Associated complaints include: nausea, belching, bloating, and epigastric burn (heartburn. All these must be scored according to severity and frequency. Furthermore, psychological factors may be involved in the origin of functional dyspepsia. On the

  1. Modeling Approach for Estimating Co-Produced Water Volumes and Saltwater Disposal Volumes in Oklahoma

    Science.gov (United States)

    Murray, K. E.

    2016-12-01

    Management of produced fluids has become an important issue in Oklahoma because large volumes of saltwater are co-produced with oil and gas, and disposed into saltwater disposal wells at high rates. Petroleum production increased from 2009-2015, especially in central and north-central Oklahoma where the Mississippian and Hunton zones were redeveloped using horizontal wells and dewatering techniques that have led to a disproportional increase in produced water volumes. Improved management of co-produced water, including desalination for beneficial reuse and decreased saltwater disposal volumes, is only possible if spatial and temporal trends can be defined and related to the producing zones. It is challenging to quantify the volumes of co-produced water by region or production zone because co-produced water volumes are generally not reported. Therefore, the goal of this research is to estimate co-produced water volumes for 2008-present with an approach that can be replicated as petroleum production shifts to other regions. Oil and gas production rates from subsurface zones were multiplied by ratios of H2O:oil and H2O:gas for the respective zones. Initial H2O:oil and H2O:gas ratios were adjusted/calibrated, by zone, to maximize correlation of county-scale produced H2O estimates versus saltwater disposal volumes from 2013-2015. These calibrated ratios were then used to compute saltwater disposal volumes from 2008-2012 because of apparent data gaps in reported saltwater disposal volumes during that timeframe. This research can be used to identify regions that have the greatest need for produced water treatment systems. The next step in management of produced fluids is to explore optimal energy-efficient strategies that reduce deleterious effects.

  2. Thermodynamic Volume Product in Spherically Symmetric and Axisymmetric Spacetime

    CERN Document Server

    Pradhan, Parthapratim

    2016-01-01

    In this Letter, we compute particularly thermodynamic \\emph{volume product, volume sum, volume minus and volume division} for wide variety of spherically symmetric spacetime and axisymmetric spacetime in the frame work of \\emph{extended phase space}. We consider Einstein gravity as well as other than Einstein gravity i.e. \\emph{Ho\\v{r}ava Lifshitz} gravity. We speculate that for spherically symmetric black holes the volume product is mass-independent both in Einstein gravity as well as Ho\\v{r}ava Lifshitz gravity while the other combination is mass-dependent. For axisymmetric black hole spacetime in Einstein gravity all the combination is \\emph{mass-dependent}. There has been no chance to generate any combination of volume product is mass-independent. Interestingly, \\emph{only rotating BTZ black hole} in 3D provides the volume product formula is mass-independent i.e. \\emph{universal} and hence it is quantized.

  3. Defining the infrared systems for ITER.

    Science.gov (United States)

    Reichle, R; Andrew, P; Counsell, G; Drevon, J-M; Encheva, A; Janeschitz, G; Johnson, D; Kusama, Y; Levesy, B; Martin, A; Pitcher, C S; Pitts, R; Thomas, D; Vayakis, G; Walsh, M

    2010-10-01

    The International Thermonuclear Experimental Reactor will have wide angle viewing systems and a divertor thermography diagnostic, which shall provide infrared coverage of the divertor and large parts of the first wall surfaces with spatial and temporal resolution adequate for operational purposes and higher resolved details of the divertor and other areas for physics investigations. We propose specifications for each system such that they jointly respond to the requirements. Risk analysis driven priorities for future work concern mirror degradation, interfaces with other diagnostics, radiation damage to refractive optics, reflections, and the development of calibration and measurement methods for varying optical and thermal target properties.

  4. Implicitly Defined Neural Networks for Sequence Labeling

    Science.gov (United States)

    2017-07-31

    struc- ture . 1.1 Related Work Long-range dependencies have been an issue as long as there have been NLP tasks, and there are many ef- fective approaches...σ(Wpxt + Upht−1 + bp) next switch sn = σ(Wnxt + Unht+1 + bn) 3 Experiments 3.1 Part-of-speech tagging Next we apply our model to a real world problem...Wall Street Journal corpus (Marcus et al., 1993), blocks 0-18, validated on 19-21, and tested on 22-24, and compared it to the results of the off-the

  5. Belief dispersion among household investors and stock trading volume

    OpenAIRE

    2011-01-01

    We study the effects of belief dispersion on stock trading volume. Unlike most of the existing work on the subject, our paper focuses on how household investors' disagreements on macroeconomic variables influence market-wide trading volume. We show that greater belief dispersion among household investors is associated with significantly higher trading volume, even after controlling for the disagreements among professional forecasters. Further, we find that the belief dispersion among househol...

  6. SLSF loop handling system. Volume I. Structural analysis. [LMFBR

    Energy Technology Data Exchange (ETDEWEB)

    Ahmed, H.; Cowie, A.; Ma, D.

    1978-10-01

    SLSF loop handling system was analyzed for deadweight and postulated dynamic loading conditions, identified in Chapters II and III in Volume I of this report, using a linear elastic static equivalent method of stress analysis. Stress analysis of the loop handling machine is presented in Volume I of this report. Chapter VII in Volume I of this report is a contribution by EG and G Co., who performed the work under ANL supervision.

  7. Sandia software guidelines. Volume 3. Standards, practices, and conventions

    Energy Technology Data Exchange (ETDEWEB)

    1986-07-01

    This volume is one in a series of Sandia Software Guidelines intended for use in producing quality software within Sandia National Laboratories. In consonance with the IEEE Standard for Software Quality Assurance Plans, this volume identifies software standards, conventions, and practices. These guidelines are the result of a collective effort within Sandia National Laboratories to define recommended deliverables and to document standards, practices, and conventions which will help ensure quality software. 66 refs., 5 figs., 6 tabs.

  8. Communication, Work Systems and HRD

    Science.gov (United States)

    Pace, R. Wayne

    2013-01-01

    Purpose: The purpose of this article is to show the foundational place that communication theory and its practice occupies in functioning work systems. Design/methodology/approach: This paper defines the word communication in terms of the creation and interpretation of displays, describes what it means to have a theoretical foundation for a…

  9. Visualization and analysis of biomaterial-centered thrombus formation within a defined crevice under flow.

    Science.gov (United States)

    Jamiolkowski, Megan A; Pedersen, Drake D; Wu, Wei-Tao; Antaki, James F; Wagner, William R

    2016-07-01

    The blood flow pathway within a device, together with the biomaterial surfaces and status of the patient's blood, are well-recognized factors in the development of thrombotic deposition and subsequent embolization. Blood flow patterns are of particular concern for devices such as blood pumps (i.e. ventricular assist devices, VADs) where shearing forces can be high, volumes are relatively large, and the flow fields can be complex. However, few studies have examined the effect of geometric irregularities on thrombus formation on clinically relevant opaque materials under flow. The objective of this study was to quantify human platelet deposition onto Ti6Al4V alloys, as well as positive and negative control surfaces, in the region of defined crevices (∼50-150 μm in width) that might be encountered in many VADs or other cardiovascular devices. To achieve this, reconstituted fresh human blood with hemoglobin-depleted red blood cells (to achieve optical clarity while maintaining relevant rheology), long working optics, and a custom designed parallel plate flow chamber were employed. The results showed that the least amount of platelet deposition occurred in the largest crevice size examined, which was counterintuitive. The greatest levels of deposition occurred in the 90 μm and 53 μm crevices at the lower wall shear rate. The results suggest that while crevices may be unavoidable in device manufacturing, the crevice size might be tailored, depending on the flow conditions, to reduce the risk of thromboembolic events. Further, these data might be used to improve the accuracy of predictive models of thrombotic deposition in cardiovascular devices to help optimize the blood flow path and reduce device thrombogenicity.

  10. Proposal to Increase Productivity of Work

    OpenAIRE

    Nikoleta Puchá; Peter Malega

    2010-01-01

    A team work is a way of the organization work based on common connection, mutual co-operation and a responsibility of the team members’ work. As benefits of the team work are considered e.g.: bigger amount of improvement - optimalization processes and decreasing cost, more effective solving problems, bigger motivation and personal growth. In the article it is reviewed the team works according to buy and sell term. We define conflicts and suggest their elimination between members of team with ...

  11. Groups definable in o-minimal structures: structure theorem, G^000, definable amenability and bounded orbits

    CERN Document Server

    Pillay, Anand

    2010-01-01

    We settle some open problems in the special case of groups in o-minimal structures, such as the equality of G^00 and G^000 and the equivalence of definable amenability and existence of a type with bounded orbit. We prove almost exactness of the G to G^00 functor. We ask further questions about types with bounded orbits in NIP theories.

  12. Engineering: Defining and differentiating its unique culture

    Science.gov (United States)

    Pilotte, Mary K.

    The world of work for engineering professionals is changing. At a rapid pace, experienced engineers are exiting the workforce due to retirement of the Baby Boomer generation, while at the same time the problems facing engineers are increasingly complex and frequently global in nature. For firms to protect their knowledge assets, they must ensure that acquired understandings are shared among their engineering work groups. Engineering teaching and learning in the workplace (i.e., knowledge sharing), is a social activity that resides in a social context governed by the professional engineering culture. This quantitative study uses Hofstede's Organizational Cultural Values Model (Hofstede, Neuijen, Ohayv, & Sanders, 1990) to examine dimensions of engineering culture in the workplace, producing a central tendency profile of engineering's cultural practices. Further, it explores through hypotheses if demographic differentiators, including birth generation, gender, race, industry sector of employment, and engineering discipline, play roles in forming engineering cultural practices. Results both corroborate aspects of Hofstede's model and assert new understandings relative to factors influencing dimensions of engineering practice. Outcomes are discussed in terms of their potential impact on industrial knowledge sharing and formation of beneficial engineering cultures.

  13. Defining urban and rural regions by multifractal spectrums of urbanization

    CERN Document Server

    Chen, Yanguang

    2015-01-01

    The spatial pattern of urban-rural regional system is associated with the dynamic process of urbanization. How to characterize the urban-rural terrain using quantitative measurement is a difficult problem remaining to be solved. This paper is devoted to defining urban and rural regions using ideas from fractals. A basic postulate is that human geographical systems are of self-similar patterns associated with recursive processes. Then multifractal geometry can be employed to describe or define the urban and rural terrain with the level of urbanization. A space-filling index of urban-rural region based on the generalized correlation dimension is presented to reflect the degree of geo-spatial utilization in terms of urbanization. The census data of America and China are adopted to show how to make empirical analyses of urban-rural multifractals. This work is not so much a positive analysis as a normative study, but it proposes a new way of investigating urban and rural regional systems using fractal theory.

  14. Human vascular model with defined stimulation medium - a characterization study.

    Science.gov (United States)

    Huttala, Outi; Vuorenpää, Hanna; Toimela, Tarja; Uotila, Jukka; Kuokkanen, Hannu; Ylikomi, Timo; Sarkanen, Jertta-Riina; Heinonen, Tuula

    2015-01-01

    The formation of blood vessels is a vital process in embryonic development and in normal physiology. Current vascular modelling is mainly based on animal biology leading to species-to-species variation when extrapolating the results to humans. Although there are a few human cell based vascular models available these assays are insufficiently characterized in terms of culture conditions and developmental stage of vascular structures. Therefore, well characterized vascular models with human relevance are needed for basic research, embryotoxicity testing, development of therapeutic strategies and for tissue engineering. We have previously shown that the in vitro vascular model based on co-culture of human adipose stromal cells (hASC) and human umbilical vein endothelial cells (HUVEC) is able to induce an extensive vascular-like network with high reproducibility. In this work we developed a defined serum-free vascular stimulation medium (VSM) and performed further characterization in terms of cell identity, maturation and structure to obtain a thoroughly characterized in vitro vascular model to replace or reduce corresponding animal experiments. The results showed that the novel vascular stimulation medium induced intact and evenly distributed vascular-like network with morphology of mature vessels. Electron microscopic analysis assured the three-dimensional microstructure of the network containing lumen. Additionally, elevated expressions of the main human angiogenesis-related genes were detected. In conclusion, with the new defined medium the vascular model can be utilized as a characterized test system for chemical testing as well as in creating vascularized tissue models.

  15. Minimizing communication cost among distributed controllers in software defined networks

    Science.gov (United States)

    Arlimatti, Shivaleela; Elbreiki, Walid; Hassan, Suhaidi; Habbal, Adib; Elshaikh, Mohamed

    2016-08-01

    Software Defined Networking (SDN) is a new paradigm to increase the flexibility of today's network by promising for a programmable network. The fundamental idea behind this new architecture is to simplify network complexity by decoupling control plane and data plane of the network devices, and by making the control plane centralized. Recently controllers have distributed to solve the problem of single point of failure, and to increase scalability and flexibility during workload distribution. Even though, controllers are flexible and scalable to accommodate more number of network switches, yet the problem of intercommunication cost between distributed controllers is still challenging issue in the Software Defined Network environment. This paper, aims to fill the gap by proposing a new mechanism, which minimizes intercommunication cost with graph partitioning algorithm, an NP hard problem. The methodology proposed in this paper is, swapping of network elements between controller domains to minimize communication cost by calculating communication gain. The swapping of elements minimizes inter and intra communication cost among network domains. We validate our work with the OMNeT++ simulation environment tool. Simulation results show that the proposed mechanism minimizes the inter domain communication cost among controllers compared to traditional distributed controllers.

  16. Defining clusters in APT reconstructions of ODS steels

    Energy Technology Data Exchange (ETDEWEB)

    Williams, Ceri A., E-mail: ceri.williams@materials.ox.ac.uk [Department of Materials, University of Oxford, Parks Road, Oxford OX1 3PH (United Kingdom); Haley, Daniel [Department of Materials, University of Oxford, Parks Road, Oxford OX1 3PH (United Kingdom); Max-Planck-Institut für Eisenforschung GmbH, Max-Planck-Straße 1, D-40237 Düsseldorf (Germany); Marquis, Emmanuelle A. [Department of Materials Science and Engineering, University of Michigan, 2300 Hayward Street, Ann Arbor, MI 48109-2136 (United States); Smith, George D.W.; Moody, Michael P. [Department of Materials, University of Oxford, Parks Road, Oxford OX1 3PH (United Kingdom)

    2013-09-15

    Oxide nanoclusters in a consolidated Fe–14Cr–2W–0.3Ti–0.3Y{sub 2}O{sub 3} ODS steel and in the alloy powder after mechanical alloying (but before consolidation) are investigated by atom probe tomography (APT). The maximum separation method is a standard method to define and characterise clusters from within APT data, but this work shows that the extent of clustering between the two materials is sufficiently different that the nanoclusters in the mechanically alloyed powder and in the consolidated material cannot be compared directly using the same cluster selection parameters. As the cluster selection parameters influence the size and composition of the clusters significantly, a procedure to optimise the input parameters for the maximum separation method is proposed by sweeping the d{sub max} and N{sub min} parameter space. By applying this method of cluster parameter selection combined with a ‘matrix correction’ to account for trajectory aberrations, differences in the oxide nanoclusters can then be reliably quantified. - Highlights: ► Oxide nanoclusters in an ODS steel are defined using the double maximum separation method. ► Clusters in ODS material at different stages during processing cannot be compared directly. ► Input parameters for the maximum separation method are optimised by an objective function. ► When combined with a ‘matrix correction’, variation in the nanoclusters can be quantified.

  17. Defining Urban and Rural Regions by Multifractal Spectrums of Urbanization

    Science.gov (United States)

    Chen, Yanguang

    2016-03-01

    The spatial pattern of the urban-rural regional system is associated with the dynamic process of urbanization. How to characterize the urban-rural terrain using quantitative measurement is a difficult problem remaining to be solved. This paper is devoted to defining urban and rural regions using ideas from fractals. A basic postulate is that human geographical systems are of self-similar patterns correlated with recursive processes. Then multifractal geometry can be employed to describe or define the urban and rural terrain with the level of urbanization. A space-filling index of urban-rural region based on a generalized correlation dimension is presented to reflect the degree of geo-spatial utilization in terms of urbanism. The census data of America and China are used to show how to make empirical analyses of urban-rural multifractals. This work is a normative study rather than a positive study, and it proposes a new way of investigating urban and rural regional systems using fractal theory.

  18. A Methodology to Define Flood Resilience

    Science.gov (United States)

    Tourbier, J.

    2012-04-01

    Flood resilience has become an internationally used term with an ever-increasing number of entries on the Internet. The SMARTeST Project is looking at approaches to flood resilience through case studies at cities in various countries, including Washington D.C. in the United States. In light of U.S. experiences a methodology is being proposed by the author that is intended to meet ecologic, spatial, structural, social, disaster relief and flood risk aspects. It concludes that: "Flood resilience combines (1) spatial, (2) structural, (3) social, and (4) risk management levels of flood preparedness." Flood resilience should incorporate all four levels, but not necessarily with equal emphasis. Stakeholders can assign priorities within different flood resilience levels and the considerations they contain, dividing 100% emphasis into four levels. This evaluation would be applied to planned and completed projects, considering existing conditions, goals and concepts. We have long known that the "road to market" for the implementation of flood resilience is linked to capacity building of stakeholders. It is a multidisciplinary enterprise, involving the integration of all the above aspects into the decision-making process. Traditional flood management has largely been influenced by what in the UK has been called "Silo Thinking", involving constituent organizations that are responsible for different elements, and are interested only in their defined part of the system. This barrier to innovation also has been called the "entrapment effect". Flood resilience is being defined as (1) SPATIAL FLOOD RESILIENCE implying the management of land by floodplain zoning, urban greening and management to reduce storm runoff through depression storage and by practicing Sustainable Urban Drainage (SUD's), Best Management Practices (BMP's, or Low Impact Development (LID). Ecologic processes and cultural elements are included. (2) STRUCTURAL FLOOD RESILIENCE referring to permanent flood defense

  19. On Memory Accelerated Signal Processing within Software Defined Radios

    CERN Document Server

    Pellegrini, Vincenzo; Di Dio, Mario

    2010-01-01

    Since J. Mitola's work in 1992, Software Defined Radios (SDRs) have been quite a hot topic in wireless systems research. Though many notable achievements were reported in the field, the scarcity of computational power on general purpose CPUs has always constrained their wide adoption in production environments. If conveniently applied within an SDR context, classical concepts known in computer science as space/time tradeoffs can be extremely helpful when trying to mitigate this problem. Inspired by and building on those concepts, this paper presents a novel SDR implementation technique which we call Memory Acceleration (MA) that makes extensive use of the memory resources available on a general purpose computing system, in order to accelerate signal computation. MA can provide substantial acceleration factors when applied to conventional SDRs without reducing their peculiar flexibility. As a practical proof of this, an example of MA applied in the real world to the ETSI DVB-T Viterbi decoder is provided. Actu...

  20. SONEP: A Software-Defined Optical Network Emulation Platform

    DEFF Research Database (Denmark)

    Azodolmolky, Siamak; Petersen, Martin Nordal; Fagertun, Anna Manolova

    2014-01-01

    Network emulation has been one of the tools of choice for conducting experiments on commodity hardware. In the absence of an easy to use optical network test-bed, researchers can significantly benefit from the availability of a flexible/programmable optical network emulation platform. Exploiting...... the lightweight system virtualization, which is recently supported in modern operating systems, in this work we present the architecture of a Software-Defined Network (SDN) emulation platform for transport optical networks and investigate its usage in a use-case scenario. To the best of our knowledge......, this is for the first time that an SDN-based emulation platform is proposed for modeling and performance evaluation of optical networks. Coupled with recent trend of extension of SDN towards transport (optical) networks, the presented tool can facilitate the evaluation of innovative idea before actual implementations...