WorldWideScience

Sample records for volume weighted average

  1. 40 CFR 63.2854 - How do I determine the weighted average volume fraction of HAP in the actual solvent loss?

    Science.gov (United States)

    2010-07-01

    ... volume fraction of HAP in the actual solvent loss? 63.2854 Section 63.2854 Protection of Environment... AIR POLLUTANTS FOR SOURCE CATEGORIES National Emission Standards for Hazardous Air Pollutants: Solvent... average volume fraction of HAP in the actual solvent loss? (a) This section describes the information and...

  2. Weighted estimates for the averaging integral operator

    Czech Academy of Sciences Publication Activity Database

    Opic, Bohumír; Rákosník, Jiří

    2010-01-01

    Roč. 61, č. 3 (2010), s. 253-262 ISSN 0010-0757 R&D Projects: GA ČR GA201/05/2033; GA ČR GA201/08/0383 Institutional research plan: CEZ:AV0Z10190503 Keywords : averaging integral operator * weighted Lebesgue spaces * weights Subject RIV: BA - General Mathematics Impact factor: 0.474, year: 2010 http://link.springer.com/article/10.1007%2FBF03191231

  3. Generalized Jackknife Estimators of Weighted Average Derivatives

    DEFF Research Database (Denmark)

    Cattaneo, Matias D.; Crump, Richard K.; Jansson, Michael

    With the aim of improving the quality of asymptotic distributional approximations for nonlinear functionals of nonparametric estimators, this paper revisits the large-sample properties of an important member of that class, namely a kernel-based weighted average derivative estimator. Asymptotic...

  4. Cosmological measure with volume averaging and the vacuum energy problem

    Science.gov (United States)

    Astashenok, Artyom V.; del Popolo, Antonino

    2012-04-01

    In this paper, we give a possible solution to the cosmological constant problem. It is shown that the traditional approach, based on volume weighting of probabilities, leads to an incoherent conclusion: the probability that a randomly chosen observer measures Λ = 0 is exactly equal to 1. Using an alternative, volume averaging measure, instead of volume weighting can explain why the cosmological constant is non-zero.

  5. Cosmological measure with volume averaging and the vacuum energy problem

    International Nuclear Information System (INIS)

    Astashenok, Artyom V; Del Popolo, Antonino

    2012-01-01

    In this paper, we give a possible solution to the cosmological constant problem. It is shown that the traditional approach, based on volume weighting of probabilities, leads to an incoherent conclusion: the probability that a randomly chosen observer measures Λ = 0 is exactly equal to 1. Using an alternative, volume averaging measure, instead of volume weighting can explain why the cosmological constant is non-zero. (paper)

  6. Asymmetric network connectivity using weighted harmonic averages

    Science.gov (United States)

    Morrison, Greg; Mahadevan, L.

    2011-02-01

    We propose a non-metric measure of the "closeness" felt between two nodes in an undirected, weighted graph using a simple weighted harmonic average of connectivity, that is a real-valued Generalized Erdös Number (GEN). While our measure is developed with a collaborative network in mind, the approach can be of use in a variety of artificial and real-world networks. We are able to distinguish between network topologies that standard distance metrics view as identical, and use our measure to study some simple analytically tractable networks. We show how this might be used to look at asymmetry in authorship networks such as those that inspired the integer Erdös numbers in mathematical coauthorships. We also show the utility of our approach to devise a ratings scheme that we apply to the data from the NetFlix prize, and find a significant improvement using our method over a baseline.

  7. Bootstrapping Density-Weighted Average Derivatives

    DEFF Research Database (Denmark)

    Cattaneo, Matias D.; Crump, Richard K.; Jansson, Michael

    Employing the "small bandwidth" asymptotic framework of Cattaneo, Crump, and Jansson (2009), this paper studies the properties of a variety of bootstrap-based inference procedures associated with the kernel-based density-weighted averaged derivative estimator proposed by Powell, Stock, and Stoker...... (1989). In many cases validity of bootstrap-based inference procedures is found to depend crucially on whether the bandwidth sequence satisfies a particular (asymptotic linearity) condition. An exception to this rule occurs for inference procedures involving a studentized estimator employing a "robust...

  8. Average weighted receiving time in recursive weighted Koch networks

    Indian Academy of Sciences (India)

    Home; Journals; Pramana – Journal of Physics; Volume 86; Issue 6 ... Nonlinear Scientific Research Center, Faculty of Science, Jiangsu University, Zhenjiang, Jiangsu, 212013, People's Republic of China; School of Computer Science and Telecommunication Engineering, Jiangsu University, Zhenjiang, 212013, People's ...

  9. Bayesian model averaging and weighted average least squares : Equivariance, stability, and numerical issues

    NARCIS (Netherlands)

    De Luca, G.; Magnus, J.R.

    2011-01-01

    In this article, we describe the estimation of linear regression models with uncertainty about the choice of the explanatory variables. We introduce the Stata commands bma and wals, which implement, respectively, the exact Bayesian model-averaging estimator and the weighted-average least-squares

  10. Bivariate copulas on the exponentially weighted moving average control chart

    Directory of Open Access Journals (Sweden)

    Sasigarn Kuvattana

    2016-10-01

    Full Text Available This paper proposes four types of copulas on the Exponentially Weighted Moving Average (EWMA control chart when observations are from an exponential distribution using a Monte Carlo simulation approach. The performance of the control chart is based on the Average Run Length (ARL which is compared for each copula. Copula functions for specifying dependence between random variables are used and measured by Kendall’s tau. The results show that the Normal copula can be used for almost all shifts.

  11. Small Bandwidth Asymptotics for Density-Weighted Average Derivatives

    DEFF Research Database (Denmark)

    Cattaneo, Matias D.; Crump, Richard K.; Jansson, Michael

    This paper proposes (apparently) novel standard error formulas for the density-weighted average derivative estimator of Powell, Stock, and Stoker (1989). Asymptotic validity of the standard errors developed in this paper does not require the use of higher-order kernels and the standard errors...

  12. Applications of ordered weighted averaging (OWA operators in environmental problems

    Directory of Open Access Journals (Sweden)

    Carlos Llopis-Albert

    2017-04-01

    Full Text Available This paper presents an application of a prioritized weighted aggregation operator based on ordered weighted averaging (OWA to deal with stakeholders' constructive participation in water resources projects. They have different degree of acceptance or preference regarding the measures and policies to be carried out, which lead to different environmental and socio-economic outcomes, and hence, to different levels of stakeholders’ satisfaction. The methodology establishes a prioritization relationship upon the stakeholders, which preferences are aggregated by means of weights depending on the satisfaction of the higher priority policy maker. The methodology establishes a prioritization relationship upon the stakeholders, which preferences are aggregated by means of weights depending on the satisfaction of the higher priority policy maker. The methodology has been successfully applied to a Public Participation Project (PPP in watershed management, thus obtaining efficient environmental measures in conflict resolution problems under actors’ preference uncertainties.

  13. Average radiation weighting factors for specific distributed neutron spectra

    International Nuclear Information System (INIS)

    Ninkovic, M.M.; Raicevic, J.J.

    1993-01-01

    Spectrum averaged radiation weighting factors for 6 specific neutron fields in the environment of 3 categories of the neutron sources (fission, spontaneous fission and (α,n)) are determined in this paper. Obtained values of these factors are greater 1.5 to 2 times than the corresponding quality factors used for the same purpose until a few years ago. This fact is very important to have in mind in the conversion of the neutron fluence into the neutron dose equivalent. (author)

  14. Nuttall Oak Volume and Weight Tables

    Science.gov (United States)

    Bryce E. Schlaegel; Regan B. Willson

    1983-01-01

    Volume and weight tables were constructed from a 62-tree sample of Nuttall oak (Quercus nuttallii Palmer) taken in the Mississippi Delta. The tables present volume, green weight, and dry weight of bole wood, bole wood plus bark, and total tree above a one-foot stump as predicted from the nonlinear model Y = 0Db

  15. 76 FR 13580 - Bus Testing; Calculation of Average Passenger Weight and Test Vehicle Weight

    Science.gov (United States)

    2011-03-14

    ... averages (See, Advisory Circular 120-27E, ``Aircraft Weight and Balance Control,'' June 10, 2005) and the...' needs, or they may choose to upgrade individual components, such as chassis, wheels, tires, brakes, or...

  16. An Exponentially Weighted Moving Average Control Chart for Bernoulli Data

    DEFF Research Database (Denmark)

    Spliid, Henrik

    2010-01-01

    of the transformation is given and its limit for small values of p is derived. Control of high yield processes is discussed and the chart is shown to perform very well in comparison with both the most common alternative EWMA chart and the CUSUM chart. The construction and the use of the proposed EWMA chart......We consider a production process in which units are produced in a sequential manner. The units can, for example, be manufactured items or services, provided to clients. Each unit produced can be a failure with probability p or a success (non-failure) with probability (1-p). A novel exponentially...... weighted moving average (EWMA) control chart intended for surveillance of the probability of failure, p, is described. The chart is based on counting the number of non-failures produced between failures in combination with a variance-stabilizing transformation. The distribution function...

  17. 76 FR 28947 - Bus Testing: Calculation of Average Passenger Weight and Test Vehicle Weight, and Public Meeting...

    Science.gov (United States)

    2011-05-19

    ...-0015] RIN 2132-AB01 Bus Testing: Calculation of Average Passenger Weight and Test Vehicle Weight, and... of proposed rulemaking (NPRM) regarding the calculation of average passenger weights and test vehicle... passenger weights and actual transit vehicle loads. Specifically, FTA proposed to change the average...

  18. Artificial Intelligence Can Predict Daily Trauma Volume and Average Acuity.

    Science.gov (United States)

    Stonko, David P; Dennis, Bradley M; Betzold, Richard D; Peetz, Allan B; Gunter, Oliver L; Guillamondegui, Oscar D

    2018-04-19

    The goal of this study was to integrate temporal and weather data in order to create an artificial neural network (ANN) to predict trauma volume, the number of emergent operative cases, and average daily acuity at a level 1 trauma center. Trauma admission data from TRACS and weather data from the National Oceanic and Atmospheric Administration (NOAA) was collected for all adult trauma patients from July 2013-June 2016. The ANN was constructed using temporal (time, day of week), and weather factors (daily high, active precipitation) to predict four points of daily trauma activity: number of traumas, number of penetrating traumas, average ISS, and number of immediate OR cases per day. We trained a two-layer feed-forward network with 10 sigmoid hidden neurons via the Levenberg-Marquardt backpropagation algorithm, and performed k-fold cross validation and accuracy calculations on 100 randomly generated partitions. 10,612 patients over 1,096 days were identified. The ANN accurately predicted the daily trauma distribution in terms of number of traumas, number of penetrating traumas, number of OR cases, and average daily ISS (combined training correlation coefficient r = 0.9018+/-0.002; validation r = 0.8899+/- 0.005; testing r = 0.8940+/-0.006). We were able to successfully predict trauma and emergent operative volume, and acuity using an ANN by integrating local weather and trauma admission data from a level 1 center. As an example, for June 30, 2016, it predicted 9.93 traumas (actual: 10), and a mean ISS score of 15.99 (actual: 13.12); see figure 3. This may prove useful for predicting trauma needs across the system and hospital administration when allocating limited resources. Level III STUDY TYPE: Prognostic/Epidemiological.

  19. Green Suppliers Performance Evaluation in Belt and Road Using Fuzzy Weighted Average with Social Media Information

    Directory of Open Access Journals (Sweden)

    Kuo-Ping Lin

    2017-12-01

    Full Text Available A decision model for selecting a suitable supplier is a key to reducing the environmental impact in green supply chain management for high-tech companies. Traditional fuzzy weight average (FWA adopts linguistic variable to determine weight by experts. However, the weights of FWA have not considered the public voice, meaning the viewpoints of consumers in green supply chain management. This paper focuses on developing a novel decision model for green supplier selection in the One Belt and One Road (OBOR initiative through a fuzzy weighted average approach with social media. The proposed decision model uses the membership grade of the criteria and sub-criteria and its relative weights, which consider the volume of social media, to establish an analysis matrix of green supplier selection. Then, the proposed fuzzy weighted average approach is considered as an aggregating tool to calculate a synthetic score for each green supplier in the Belt and Road initiative. The final score of the green supplier is ordered by a non-fuzzy performance value ranking method to help the consumer make a decision. A case of green supplier selection in the light-emitting diode (LED industry is used to demonstrate the proposed decision model. The findings demonstrate (1 the consumer’s main concerns are the “Quality” and “Green products” in LED industry, hence, the ranking of suitable supplier in FWA with social media information model obtained the difference result with tradition FWA; (2 OBOR in the LED industry is not fervently discussed in searches of Google and Twitter; and (3 the FWA with social media information could objectively analyze the green supplier selection because the novel model considers the viewpoints of the consumer.

  20. Modelling lidar volume-averaging and its significance to wind turbine wake measurements

    Science.gov (United States)

    Meyer Forsting, A. R.; Troldborg, N.; Borraccino, A.

    2017-05-01

    Lidar velocity measurements need to be interpreted differently than conventional in-situ readings. A commonly ignored factor is “volume-averaging”, which refers to lidars not sampling in a single, distinct point but along its entire beam length. However, especially in regions with large velocity gradients, like the rotor wake, can it be detrimental. Hence, an efficient algorithm mimicking lidar flow sampling is presented, which considers both pulsed and continous-wave lidar weighting functions. The flow-field around a 2.3 MW turbine is simulated using Detached Eddy Simulation in combination with an actuator line to test the algorithm and investigate the potential impact of volume-averaging. Even with very few points discretising the lidar beam is volume-averaging captured accurately. The difference in a lidar compared to a point measurement is greatest at the wake edges and increases from 30% one rotor diameter (D) downstream of the rotor to 60% at 3D.

  1. 12 CFR 702.105 - Weighted-average life of investments.

    Science.gov (United States)

    2010-01-01

    ... investment funds. (1) For investments in registered investment companies (e.g., mutual funds) and collective investment funds, the weighted-average life is defined as the maximum weighted-average life disclosed, directly or indirectly, in the prospectus or trust instrument; (2) For investments in money market funds...

  2. “Simpson’s paradox” as a manifestation of the properties of weighted average (part 2)

    OpenAIRE

    Zhekov, Encho

    2012-01-01

    The article proves that the so-called “Simpson's paradox” is a special case of manifestation of the properties of weighted average. In this case always comes to comparing two weighted averages, where the average of the larger variables is less than that of the smaller. The article demonstrates one method for analyzing the relative change of magnitudes of the type: k S = Σ x iy i i=1 who gives answer to question: what is the reason, the weighted average of few variables with higher values, to ...

  3. “Simpson’s paradox” as a manifestation of the properties of weighted average (part 1)

    OpenAIRE

    Zhekov, Encho

    2012-01-01

    The article proves that the so-called “Simpson's paradox” is a special case of manifestation of the properties of weighted average. In this case always comes to comparing two weighted averages, where the average of the larger variables is less than that of the smaller. The article demonstrates one method for analyzing the relative change of magnitudes of the type: S = Σ ki=1x iy i who gives answer to question: what is the reason, the weighted average of few variables with higher values, to be...

  4. Volume-weighted measure for eternal inflation

    International Nuclear Information System (INIS)

    Winitzki, Sergei

    2008-01-01

    I propose a new volume-weighted probability measure for cosmological 'multiverse' scenarios involving eternal inflation. The 'reheating-volume (RV) cutoff' calculates the distribution of observable quantities on a portion of the reheating hypersurface that is conditioned to be finite. The RV measure is gauge-invariant, does not suffer from the 'youngness paradox', and is independent of initial conditions at the beginning of inflation. In slow-roll inflationary models with a scalar inflaton, the RV-regulated probability distributions can be obtained by solving nonlinear diffusion equations. I discuss possible applications of the new measure to 'landscape' scenarios with bubble nucleation. As an illustration, I compute the predictions of the RV measure in a simple toy landscape.

  5. Focused information criterion and model averaging based on weighted composite quantile regression

    KAUST Repository

    Xu, Ganggang; Wang, Suojin; Huang, Jianhua Z.

    2013-01-01

    We study the focused information criterion and frequentist model averaging and their application to post-model-selection inference for weighted composite quantile regression (WCQR) in the context of the additive partial linear models. With the non

  6. Analysis of litter size and average litter weight in pigs using a recursive model

    DEFF Research Database (Denmark)

    Varona, Luis; Sorensen, Daniel; Thompson, Robin

    2007-01-01

    An analysis of litter size and average piglet weight at birth in Landrace and Yorkshire using a standard two-trait mixed model (SMM) and a recursive mixed model (RMM) is presented. The RMM establishes a one-way link from litter size to average piglet weight. It is shown that there is a one......-to-one correspondence between the parameters of SMM and RMM and that they generate equivalent likelihoods. As parameterized in this work, the RMM tests for the presence of a recursive relationship between additive genetic values, permanent environmental effects, and specific environmental effects of litter size......, on average piglet weight. The equivalent standard mixed model tests whether or not the covariance matrices of the random effects have a diagonal structure. In Landrace, posterior predictive model checking supports a model without any form of recursion or, alternatively, a SMM with diagonal covariance...

  7. Children’s Attitudes and Stereotype Content Toward Thin, Average-Weight, and Overweight Peers

    Directory of Open Access Journals (Sweden)

    Federica Durante

    2014-05-01

    Full Text Available Six- to 11-year-old children’s attitudes toward thin, average-weight, and overweight targets were investigated with associated warmth and competence stereotypes. The results showed positive attitudes toward average-weight targets and negative attitudes toward overweight peers: Both attitudes decreased as a function of children’s age. Thin targets were perceived more positively than overweight ones but less positively than average-weight targets. Notably, social desirability concerns predicted the decline of anti-fat bias in older children. Finally, the results showed ambivalent stereotypes toward thin and overweight targets—particularly among older children—mirroring the stereotypes observed in adults. This result suggests that by the end of elementary school, children manage the two fundamental dimensions of social judgment similar to adults.

  8. Effect of various solvents on the viscosity-average molecular weight of poly (vinyl acetate)

    International Nuclear Information System (INIS)

    Rehman, W.U.; But, M.A.; Chughtai, A.; Jamil, T.; Sattar, A.

    2006-01-01

    Solution polymerization of Vinyl Acetate was carried out in various solvents (benzene, toluene, ethyl acetate, acetonitrile). Dilute solution viscometry was used to determine the viscosity-average molecular weight of the resulting Poly (Vinyl Acetate) (PV Ac) in each case. The viscosity-average molecular weight (M,J of PVAc was found to increase in the order benzene < toluene < ethyl acetate < acetonitrile, It was concluded that under the same reaction conditions (polymerization time, initiator quantity, solvent/monomer ratio, temperature), acetonitrile served as the best solvent for solution. polymerization of Vinyl Acetate monomer. (author)

  9. Analysis of photosynthate translocation velocity and measurement of weighted average velocity in transporting pathway of crops

    International Nuclear Information System (INIS)

    Ge Cailin; Luo Shishi; Gong Jian; Zhang Hao; Ma Fei

    1996-08-01

    The translocation profile pattern of 14 C-photosynthate along the transporting pathway in crops were monitored by pulse-labelling a mature leaf with 14 CO 2 . The progressive spreading of translocation profile pattern along the sheath or stem indicates that the translocation of photosynthate along the sheath or stem proceed with a range of velocities rather than with just a single velocity. The method for measuring the weighted average velocity of photosynthate translocation along the sheath or stem was established in living crops. The weighted average velocity and the maximum velocity of photosynthate translocation along the sheath in rice and maize were measured actually. (4 figs., 3 tabs.)

  10. Determination of viscosity-average molecular weight of chitosan using intrinsic viscosity measurement

    International Nuclear Information System (INIS)

    Norzita Yacob; Norhashidah Talip; Maznah Mahmud; Nurul Aizam Idayu Mat Sani; Nor Akma Samsuddin; Norafifah Ahmad Fabillah

    2013-01-01

    Determination of molecular weight by intrinsic viscosity measurement is a simple method for characterization of chitosan. To study the effect of radiation on molecular weight, chitosan was first irradiated using electron beam at different doses prior to measurement. Different concentrations of chitosan were prepared and measurement was done at room temperature. The flow time data was used to calculate the intrinsic viscosity by extrapolating the reduced viscosity to zero concentration. The value of intrinsic viscosity was then recalculated into the viscosity-average molecular weight using Mark-Houwink equation. (Author)

  11. Determination of Viscosity-Average Molecular Weight of Chitosan using Intrinsic Viscosity Measurement

    International Nuclear Information System (INIS)

    Norzita Yacob; Norhashidah Talip; Maznah Mahmud

    2011-01-01

    Molecular weight of chitosan can be determined by different techniques such as Gel Permeation Chromatography (GPC), Static Light Scattering (SLS) and intrinsic viscosity measurement. Determination of molecular weight by intrinsic viscosity measurement is a simple method for characterization of chitosan. Different concentrations of chitosan were prepared and measurement was done at room temperature. The flow time data was used to calculate the intrinsic viscosity by extrapolating the reduced viscosity to zero concentration. The value of intrinsic viscosity was then recalculated into the viscosity-average molecular weight using Mark-Houwink equation. (author)

  12. Proton transport properties of poly(aspartic acid) with different average molecular weights

    Energy Technology Data Exchange (ETDEWEB)

    Nagao, Yuki, E-mail: ynagao@kuchem.kyoto-u.ac.j [Department of Mechanical Systems and Design, Graduate School of Engineering, Tohoku University, 6-6-01 Aoba Aramaki, Aoba-ku, Sendai 980-8579 (Japan); Imai, Yuzuru [Institute of Development, Aging and Cancer (IDAC), Tohoku University, 4-1 Seiryo-cho, Aoba-ku, Sendai 980-8575 (Japan); Matsui, Jun [Institute of Multidisciplinary Research for Advanced Materials (IMRAM), Tohoku University, 2-1-1 Katahira, Sendai 980-8577 (Japan); Ogawa, Tomoyuki [Department of Electronic Engineering, Graduate School of Engineering, Tohoku University, 6-6-05 Aoba Aramaki, Aoba-ku, Sendai 980-8579 (Japan); Miyashita, Tokuji [Institute of Multidisciplinary Research for Advanced Materials (IMRAM), Tohoku University, 2-1-1 Katahira, Sendai 980-8577 (Japan)

    2011-04-15

    Research highlights: Seven polymers with different average molecular weights were synthesized. The proton conductivity depended on the number-average degree of polymerization. The difference of the proton conductivities was more than one order of magnitude. The number-average molecular weight contributed to the stability of the polymer. - Abstract: We synthesized seven partially protonated poly(aspartic acids)/sodium polyaspartates (P-Asp) with different average molecular weights to study their proton transport properties. The number-average degree of polymerization (DP) for each P-Asp was 30 (P-Asp30), 115 (P-Asp115), 140 (P-Asp140), 160 (P-Asp160), 185 (P-Asp185), 205 (P-Asp205), and 250 (P-Asp250). The proton conductivity depended on the number-average DP. The maximum and minimum proton conductivities under a relative humidity of 70% and 298 K were 1.7 . 10{sup -3} S cm{sup -1} (P-Asp140) and 4.6 . 10{sup -4} S cm{sup -1} (P-Asp250), respectively. Differential thermogravimetric analysis (TG-DTA) was carried out for each P-Asp. The results were classified into two categories. One exhibited two endothermic peaks between t = (270 and 300) {sup o}C, the other exhibited only one peak. The P-Asp group with two endothermic peaks exhibited high proton conductivity. The high proton conductivity is related to the stability of the polymer. The number-average molecular weight also contributed to the stability of the polymer.

  13. Robust Data-Driven Inference for Density-Weighted Average Derivatives

    DEFF Research Database (Denmark)

    Cattaneo, Matias D.; Crump, Richard K.; Jansson, Michael

    This paper presents a new data-driven bandwidth selector compatible with the small bandwidth asymptotics developed in Cattaneo, Crump, and Jansson (2009) for density- weighted average derivatives. The new bandwidth selector is of the plug-in variety, and is obtained based on a mean squared error...

  14. Using exponentially weighted moving average algorithm to defend against DDoS attacks

    CSIR Research Space (South Africa)

    Machaka, P

    2016-11-01

    Full Text Available This paper seeks to investigate the performance of the Exponentially Weighted Moving Average (EWMA) for mining big data and detection of DDoS attacks in Internet of Things (IoT) infrastructure. The paper will investigate the tradeoff between...

  15. Exponentially Weighted Moving Average Chart as a Suitable Tool for Nuchal Translucency Quality Review

    Czech Academy of Sciences Publication Activity Database

    Hynek, M.; Smetanová, D.; Stejskal, D.; Zvárová, Jana

    2014-01-01

    Roč. 34, č. 4 (2014), s. 367-376 ISSN 0197-3851 Institutional support: RVO:67985807 Keywords : nuchal translucency * exponentially weighted moving average model * statistics Subject RIV: BB - Applied Statistics, Operational Research Impact factor: 3.268, year: 2014

  16. An inequality between the weighted average and the rowwise correlation coefficient for proximity matrices

    NARCIS (Netherlands)

    Krijnen, WP

    De Vries (1993) discusses Pearson's product-moment correlation, Spearman's rank correlation, and Kendall's rank-correlation coefficient for assessing the association between the rows of two proximity matrices. For each of these he introduces a weighted average variant and a rowwise variant. In this

  17. AN INEQUALITY BETWEEN THE WEIGHTED AVERAGE AND THE ROWWISE CORRELATION-COEFFICIENT FOR PROXIMITY MATRICES

    NARCIS (Netherlands)

    KRIJNEN, WP

    De Vries (1993) discusses Pearson's product-moment correlation, Spearman's rank correlation, and Kendall's rank-correlation coefficient for assessing the association between the rows of two proximity matrices. For each of these he introduces a weighted average variant and a rowwise variant. In this

  18. A RED modified weighted moving average for soft real-time application

    Directory of Open Access Journals (Sweden)

    Domanśka Joanna

    2014-09-01

    Full Text Available The popularity of TCP/IP has resulted in an increase in usage of best-effort networks for real-time communication. Much effort has been spent to ensure quality of service for soft real-time traffic over IP networks. The Internet Engineering Task Force has proposed some architecture components, such as Active Queue Management (AQM. The paper investigates the influence of the weighted moving average on packet waiting time reduction for an AQM mechanism: the RED algorithm. The proposed method for computing the average queue length is based on a difference equation (a recursive equation. Depending on a particular optimality criterion, proper parameters of the modified weighted moving average function can be chosen. This change will allow reducing the number of violations of timing constraints and better use of this mechanism for soft real-time transmissions. The optimization problem is solved through simulations performed in OMNeT++ and later verified experimentally on a Linux implementation

  19. The relationship between limit of Dysphagia and average volume per swallow in patients with Parkinson's disease.

    Science.gov (United States)

    Belo, Luciana Rodrigues; Gomes, Nathália Angelina Costa; Coriolano, Maria das Graças Wanderley de Sales; de Souza, Elizabete Santos; Moura, Danielle Albuquerque Alves; Asano, Amdore Guescel; Lins, Otávio Gomes

    2014-08-01

    The goal of this study was to obtain the limit of dysphagia and the average volume per swallow in patients with mild to moderate Parkinson's disease (PD) but without swallowing complaints and in normal subjects, and to investigate the relationship between them. We hypothesize there is a direct relationship between these two measurements. The study included 10 patients with idiopathic PD and 10 age-matched normal controls. Surface electromyography was recorded over the suprahyoid muscle group. The limit of dysphagia was obtained by offering increasing volumes of water until piecemeal deglutition occurred. The average volume per swallow was calculated by dividing the time taken by the number of swallows used to drink 100 ml of water. The PD group showed a significantly lower dysphagia limit and lower average volume per swallow. There was a significantly moderate direct correlation and association between the two measurements. About half of the PD patients had an abnormally low dysphagia limit and average volume per swallow, although none had spontaneously related swallowing problems. Both measurements may be used as a quick objective screening test for the early identification of swallowing alterations that may lead to dysphagia in PD patients, but the determination of the average volume per swallow is much quicker and simpler.

  20. Focused information criterion and model averaging based on weighted composite quantile regression

    KAUST Repository

    Xu, Ganggang

    2013-08-13

    We study the focused information criterion and frequentist model averaging and their application to post-model-selection inference for weighted composite quantile regression (WCQR) in the context of the additive partial linear models. With the non-parametric functions approximated by polynomial splines, we show that, under certain conditions, the asymptotic distribution of the frequentist model averaging WCQR-estimator of a focused parameter is a non-linear mixture of normal distributions. This asymptotic distribution is used to construct confidence intervals that achieve the nominal coverage probability. With properly chosen weights, the focused information criterion based WCQR estimators are not only robust to outliers and non-normal residuals but also can achieve efficiency close to the maximum likelihood estimator, without assuming the true error distribution. Simulation studies and a real data analysis are used to illustrate the effectiveness of the proposed procedure. © 2013 Board of the Foundation of the Scandinavian Journal of Statistics..

  1. A Divergence Median-based Geometric Detector with A Weighted Averaging Filter

    Science.gov (United States)

    Hua, Xiaoqiang; Cheng, Yongqiang; Li, Yubo; Wang, Hongqiang; Qin, Yuliang

    2018-01-01

    To overcome the performance degradation of the classical fast Fourier transform (FFT)-based constant false alarm rate detector with the limited sample data, a divergence median-based geometric detector on the Riemannian manifold of Heimitian positive definite matrices is proposed in this paper. In particular, an autocorrelation matrix is used to model the correlation of sample data. This method of the modeling can avoid the poor Doppler resolution as well as the energy spread of the Doppler filter banks result from the FFT. Moreover, a weighted averaging filter, conceived from the philosophy of the bilateral filtering in image denoising, is proposed and combined within the geometric detection framework. As the weighted averaging filter acts as the clutter suppression, the performance of the geometric detector is improved. Numerical experiments are given to validate the effectiveness of our proposed method.

  2. Gamma-Weighted Discrete Ordinate Two-Stream Approximation for Computation of Domain Averaged Solar Irradiance

    Science.gov (United States)

    Kato, S.; Smith, G. L.; Barker, H. W.

    2001-01-01

    An algorithm is developed for the gamma-weighted discrete ordinate two-stream approximation that computes profiles of domain-averaged shortwave irradiances for horizontally inhomogeneous cloudy atmospheres. The algorithm assumes that frequency distributions of cloud optical depth at unresolved scales can be represented by a gamma distribution though it neglects net horizontal transport of radiation. This algorithm is an alternative to the one used in earlier studies that adopted the adding method. At present, only overcast cloudy layers are permitted.

  3. Optimal transformation for correcting partial volume averaging effects in magnetic resonance imaging

    International Nuclear Information System (INIS)

    Soltanian-Zadeh, H.; Windham, J.P.; Yagle, A.E.

    1993-01-01

    Segmentation of a feature of interest while correcting for partial volume averaging effects is a major tool for identification of hidden abnormalities, fast and accurate volume calculation, and three-dimensional visualization in the field of magnetic resonance imaging (MRI). The authors present the optimal transformation for simultaneous segmentation of a desired feature and correction of partial volume averaging effects, while maximizing the signal-to-noise ratio (SNR) of the desired feature. It is proved that correction of partial volume averaging effects requires the removal of the interfering features from the scene. It is also proved that correction of partial volume averaging effects can be achieved merely by a linear transformation. It is finally shown that the optimal transformation matrix is easily obtained using the Gram-Schmidt orthogonalization procedure, which is numerically stable. Applications of the technique to MRI simulation, phantom, and brain images are shown. They show that in all cases the desired feature is segmented from the interfering features and partial volume information is visualized in the resulting transformed images

  4. Derivation of a volume-averaged neutron diffusion equation; Atomos para el desarrollo de Mexico

    Energy Technology Data Exchange (ETDEWEB)

    Vazquez R, R.; Espinosa P, G. [UAM-Iztapalapa, Av. San Rafael Atlixco 186, Col. Vicentina, Mexico D.F. 09340 (Mexico); Morales S, Jaime B. [UNAM, Laboratorio de Analisis en Ingenieria de Reactores Nucleares, Paseo Cuauhnahuac 8532, Jiutepec, Morelos 62550 (Mexico)]. e-mail: rvr@xanum.uam.mx

    2008-07-01

    This paper presents a general theoretical analysis of the problem of neutron motion in a nuclear reactor, where large variations on neutron cross sections normally preclude the use of the classical neutron diffusion equation. A volume-averaged neutron diffusion equation is derived which includes correction terms to diffusion and nuclear reaction effects. A method is presented to determine closure-relationships for the volume-averaged neutron diffusion equation (e.g., effective neutron diffusivity). In order to describe the distribution of neutrons in a highly heterogeneous configuration, it was necessary to extend the classical neutron diffusion equation. Thus, the volume averaged diffusion equation include two corrections factor: the first correction is related with the absorption process of the neutron and the second correction is a contribution to the neutron diffusion, both parameters are related to neutron effects on the interface of a heterogeneous configuration. (Author)

  5. A note on stereological estimation of the volume-weighted second moment of particle volume

    DEFF Research Database (Denmark)

    Jensen, E B; Sørensen, Flemming Brandt

    1991-01-01

    It is shown that for a variety of biological particle shapes, the volume-weighted second moment of particle volume can be estimated stereologically using only the areas of particle transects, which can be estimated manually by point-counting....

  6. Tree-average distances on certain phylogenetic networks have their weights uniquely determined.

    Science.gov (United States)

    Willson, Stephen J

    2012-01-01

    A phylogenetic network N has vertices corresponding to species and arcs corresponding to direct genetic inheritance from the species at the tail to the species at the head. Measurements of DNA are often made on species in the leaf set, and one seeks to infer properties of the network, possibly including the graph itself. In the case of phylogenetic trees, distances between extant species are frequently used to infer the phylogenetic trees by methods such as neighbor-joining. This paper proposes a tree-average distance for networks more general than trees. The notion requires a weight on each arc measuring the genetic change along the arc. For each displayed tree the distance between two leaves is the sum of the weights along the path joining them. At a hybrid vertex, each character is inherited from one of its parents. We will assume that for each hybrid there is a probability that the inheritance of a character is from a specified parent. Assume that the inheritance events at different hybrids are independent. Then for each displayed tree there will be a probability that the inheritance of a given character follows the tree; this probability may be interpreted as the probability of the tree. The tree-average distance between the leaves is defined to be the expected value of their distance in the displayed trees. For a class of rooted networks that includes rooted trees, it is shown that the weights and the probabilities at each hybrid vertex can be calculated given the network and the tree-average distances between the leaves. Hence these weights and probabilities are uniquely determined. The hypotheses on the networks include that hybrid vertices have indegree exactly 2 and that vertices that are not leaves have a tree-child.

  7. Accurate measurement of imaging photoplethysmographic signals based camera using weighted average

    Science.gov (United States)

    Pang, Zongguang; Kong, Lingqin; Zhao, Yuejin; Sun, Huijuan; Dong, Liquan; Hui, Mei; Liu, Ming; Liu, Xiaohua; Liu, Lingling; Li, Xiaohui; Li, Rongji

    2018-01-01

    Imaging Photoplethysmography (IPPG) is an emerging technique for the extraction of vital signs of human being using video recordings. IPPG technology with its advantages like non-contact measurement, low cost and easy operation has become one research hot spot in the field of biomedicine. However, the noise disturbance caused by non-microarterial area cannot be removed because of the uneven distribution of micro-arterial, different signal strength of each region, which results in a low signal noise ratio of IPPG signals and low accuracy of heart rate. In this paper, we propose a method of improving the signal noise ratio of camera-based IPPG signals of each sub-region of the face using a weighted average. Firstly, we obtain the region of interest (ROI) of a subject's face based camera. Secondly, each region of interest is tracked and feature-based matched in each frame of the video. Each tracked region of face is divided into 60x60 pixel block. Thirdly, the weights of PPG signal of each sub-region are calculated, based on the signal-to-noise ratio of each sub-region. Finally, we combine the IPPG signal from all the tracked ROI using weighted average. Compared with the existing approaches, the result shows that the proposed method takes modest but significant effects on improvement of signal noise ratio of camera-based PPG estimated and accuracy of heart rate measurement.

  8. Calculation of weighted averages approach for the estimation of ping tolerance values

    Science.gov (United States)

    Silalom, S.; Carter, J.L.; Chantaramongkol, P.

    2010-01-01

    A biotic index was created and proposed as a tool to assess water quality in the Upper Mae Ping sub-watersheds. The Ping biotic index was calculated by utilizing Ping tolerance values. This paper presents the calculation of Ping tolerance values of the collected macroinvertebrates. Ping tolerance values were estimated by a weighted averages approach based on the abundance of macroinvertebrates and six chemical constituents that include conductivity, dissolved oxygen, biochemical oxygen demand, ammonia nitrogen, nitrate nitrogen and orthophosphate. Ping tolerance values range from 0 to 10. Macroinvertebrates assigned a 0 are very sensitive to organic pollution while macroinvertebrates assigned 10 are highly tolerant to pollution.

  9. Online Self-Organizing Network Control with Time Averaged Weighted Throughput Objective

    Directory of Open Access Journals (Sweden)

    Zhicong Zhang

    2018-01-01

    Full Text Available We study an online multisource multisink queueing network control problem characterized with self-organizing network structure and self-organizing job routing. We decompose the self-organizing queueing network control problem into a series of interrelated Markov Decision Processes and construct a control decision model for them based on the coupled reinforcement learning (RL architecture. To maximize the mean time averaged weighted throughput of the jobs through the network, we propose a reinforcement learning algorithm with time averaged reward to deal with the control decision model and obtain a control policy integrating the jobs routing selection strategy and the jobs sequencing strategy. Computational experiments verify the learning ability and the effectiveness of the proposed reinforcement learning algorithm applied in the investigated self-organizing network control problem.

  10. Analisis Prioritas Pembangunan Embung Metode Cluster Analysis, AHP dan Weighted Average (Studi Kasus: Embung di Kabupaten Semarang

    Directory of Open Access Journals (Sweden)

    Bima Anjasmoro

    2016-06-01

    Full Text Available The Feasibility study potential of small dams in Semarang District has identified 8 (eight urgent potential small dams. These potential dams here to be constructed within 5 (five years in order to overcome the problem of water shortage in the district. However, the government has limited funding source. It is necessary to select the more urgent small dams to be constructed within the limited budget. The purpose of the research is determining the priority of small dams construction in Semarang District. The method used to determine the priority in this study is cluster analysis, AHP and weighted average method. The criteria used to determine the priority in this study consist of: vegetation in the inundated area, volume of embankment, land acquisition area, useful storage, recervoir life time, water cost/m³, access road to the dam site, land status at abutment and inundated area, construction cost, operation and maintenance cost, irrigation service area and raw water benefit. Based on results of cluster analysis, AHP and weighted average method can be conclude that the priority of small dams construction is 1 Mluweh Small Dam (0.165, 2 Pakis Small Dam (0.142, 3 Lebak Small Dam (0.134, 4 Dadapayam Small Dam (0.128, 5 Gogodalem Small Dam (0.119, 6 Kandangan Small Dam (0.114, 7 Ngrawan Small Dam (0.102 and 8 Jatikurung Small Dam (0.096. Based on analysis of the order of priority of 3 (three method showed that method is more detail than cluster analysis method and weighted average method, because the result of AHP method is closer to the conditions of each dam in the field.

  11. THE ASSESSMENT OF CORPORATE BONDS ON THE BASIS OF THE WEIGHTED AVERAGE

    Directory of Open Access Journals (Sweden)

    Victor V. Prokhorov

    2014-01-01

    Full Text Available The article considers the problem associated with the assessment of the interest rate of a public corporate bond issue. The theme of research is the study of techniques for evaluationof interest rates of corporate bond. The article discusses the task of developing a methodology for assessing the marketinterest rate of corporate bonded loan, which allows to takeinto account the systematic and specific risks. The technique of evaluation of market interest rates of corporate bonds onthe basis of weighted averages is proposed. This procedure uses in the calculation of cumulative barrier interest rate, sectoral weighted average interest rate and the interest ratedetermined on the basis of the model CAPM (Capital Asset Pricing Model. The results, which enable to speak about the possibility of applying the proposed methodology for assessing the market interest rate of a public corporate bond issuein the Russian conditions. The results may be applicable for Russian industrial enterprises, organizing issue public bonds,as well as investment companies exposed organizers of corporate securities loans and other organizations specializingin investments in the Russian public corporate bond loans.

  12. Extending a Consensus-based Fuzzy Ordered Weighting Average (FOWA Model in New Water Quality Indices

    Directory of Open Access Journals (Sweden)

    Mohammad Ali Baghapour

    2017-07-01

    Full Text Available In developing a specific WQI (Water Quality Index, many water quality parameters are involved with different levels of importance. The impact of experts’ different opinions and viewpoints, current risks affecting their opinions, and plurality of the involved parameters double the significance of the issue. Hence, the current study tries to apply a consensus-based FOWA (Fuzzy Ordered Weighting Average model as one of the most powerful and well-known Multi Criteria Decision Making (MCDM techniques to determine the importance of the used parameters in the development of such WQIs which is shown with an example. This operator has provided the capability of modeling the risks in decision-making through applying the optimistic degree of stakeholders and their power coupled with the use of fuzzy numbers. Totally, 22 water quality parameters for drinking purposes are considered in this study. To determine the weight of each parameter, the viewpoints of 4 decision-making groups of experts are taken into account. After determining the final weights, to validate the use of each parameter in a potential WQI, consensus degrees of both the decision makers and the parameters are calculated. All calculations are carried out by using the expertise software called Group Fuzzy Decision Making (GFDM. The highest and the lowest weight values, 0.999 and 0.073 respectively, are related to Hg and temperature. Regarding the type of consumption that is drinking, the parameters’ weights and ranks are consistent with their health impacts. Moreover, the decision makers’ highest and lowest consensus degrees were 0.9905 and 0.9669, respectively. Among the water quality parameters, temperature (with consensus degree of 0.9972 and Pb (with consensus degree of 0.9665, received the highest and lowest agreement from the decision making group. This study indicates that the weight of parameters in determining water quality largely depends on the experts’ opinions and

  13. Extending a Consensus-based Fuzzy Ordered Weighting Average (FOWA Model in New Water Quality Indices

    Directory of Open Access Journals (Sweden)

    Mohammad Ali Baghapour

    2017-07-01

    Full Text Available In developing a specific WQI (Water Quality Index, many quality parameters are involved with different levels of importance. The impact of experts’ different opinions and viewpoints, current risks affecting their opinions, and plurality of the involved parameters double the significance of the issue. Hence, the current study tries to apply a consensus-based FOWA (Fuzzy Ordered Weighting Average model as one of the most powerful and well-known Multi-Criteria Decision- Making (MCDM techniques to determine the importance of the used parameters in the development of such WQIs which is shown with an example. This operator has provided the capability of modeling the risks in decision-making through applying the optimistic degree of stakeholders and their power coupled with the use of fuzzy numbers. Totally, 22 water quality parameters for drinking purposes were considered in this study. To determine the weight of each parameter, the viewpoints of 4 decision-making groups of experts were taken into account. After determining the final weights, to validate the use of each parameter in a potential WQI, consensus degrees of both the decision makers and the parameters are calculated. The highest and the lowest weight values, 0.999 and 0.073 respectively, were related to Hg and temperature. Regarding the type of consumption that was drinking, the parameters’ weights and ranks were consistent with their health impacts. Moreover, the decision makers’ highest and lowest consensus degrees were 0.9905 and 0.9669, respectively. Among the water quality parameters, temperature (with consensus degree of 0.9972 and Pb (with consensus degree of 0.9665, received the highest and lowest agreement with the decision-making group. This study indicated that the weight of parameters in determining water quality largely depends on the experts’ opinions and approaches. Moreover, using the FOWA model provides results accurate and closer- to-reality on the significance of

  14. Fuzzy weighted average based on left and right scores in Malaysia tourism industry

    Science.gov (United States)

    Kamis, Nor Hanimah; Abdullah, Kamilah; Zulkifli, Muhammad Hazim; Sahlan, Shahrazali; Mohd Yunus, Syaizzal

    2013-04-01

    Tourism is known as an important sector to the Malaysian economy including economic generator, creating business and job offers. It is reported to bring in almost RM30 billion of the national income, thanks to intense worldwide promotion by Tourism Malaysia. One of the well-known attractions in Malaysia is our beautiful islands. The islands continue to be developed into tourist spots and attracting a continuous number of tourists. Chalets, luxury bungalows and resorts quickly develop along the coastlines of popular islands like Tioman, Redang, Pangkor, Perhentian, Sibu and so many others. In this study, we applied Fuzzy Weighted Average (FWA) method based on left and right scores in order to determine the criteria weights and to select the best island in Malaysia. Cost, safety, attractive activities, accommodation and scenery are five main criteria to be considered and five selected islands in Malaysia are taken into accounts as alternatives. The most important criteria that have been considered by the tourist are defined based on criteria weights ranking order and the best island in Malaysia is then determined in terms of FWA values. This pilot study can be used as a reference to evaluate performances or solving any selection problems, where more criteria, alternatives and decision makers will be considered in the future.

  15. MRI estimation of total renal volume demonstrates significant association with healthy donor weight

    International Nuclear Information System (INIS)

    Cohen, Emil I.; Kelly, Sarah A.; Edye, Michael; Mitty, Harold A.; Bromberg, Jonathan S.

    2009-01-01

    Purpose: The purpose of this study was to correlate total renal volume (TRV) calculations, obtained through the voxel-count method and ellipsoid formula with various physical characteristics. Materials and methods: MRI reports and physical examination from 210 healthy kidney donors (420 kidneys), on whom renal volumes were obtained using the voxel-count method, were retrospectively reviewed. These values along with ones obtained through a more traditional method (ellipsoid formula) were correlated with subject height, body weight, body mass index (BMI), and age. Results: TRV correlated strongly with body weight (r = 0.7) and to a lesser degree with height, age, or BMI (r = 0.5, -0.2, 0.3, respectively). The left kidney volume was greater than the right, on average (p < 0.001). The ellipsoid formula method over-estimated renal volume by 17% on average which was significant (p < 0.001). Conclusions: Body weight was the physical characteristic which demonstrated the strongest correlation with renal volume in healthy subjects. Given this finding, a formula was derived for estimating the TRV for a given patient based on the his or her weight: TRV = 2.96 x weight (kg) + 113 ± 64.

  16. Determination of average fission fraction produced by 14 MeV neutrons in assemblies with large volume of depleted uranium

    International Nuclear Information System (INIS)

    Wang Dalun; Li Benci; Wang Xiuchun; Li Yijun; Zhang Shaohua; He Yongwu

    1991-07-01

    The average fission fraction of 238 U caused by 14 MeV neutrons in assemblies with large volume depleted uranium has been determined. The measured value of p f 238U (R ∞ depleted ) 14 was 0.897 ± 0.036. Measurements were also completed for neutron flux distribution and average fission fraction of 235 U isotope in depleted uranium sphere. Values of p f 238U (R depleted ) have been obtained by using a series of uranium spheres. For a sphere with Φ 600 the p f 23 '8 U (R 300 depleted ) is 0.823 ± 0.041, the density of depleted uranium assembly is 18.8g/cm 3 and total weight of assembly is about 2.8t

  17. Adaptive polarization image fusion based on regional energy dynamic weighted average

    Institute of Scientific and Technical Information of China (English)

    ZHAO Yong-qiang; PAN Quan; ZHANG Hong-cai

    2005-01-01

    According to the principle of polarization imaging and the relation between Stokes parameters and the degree of linear polarization, there are much redundant and complementary information in polarized images. Since man-made objects and natural objects can be easily distinguished in images of degree of linear polarization and images of Stokes parameters contain rich detailed information of the scene, the clutters in the images can be removed efficiently while the detailed information can be maintained by combining these images. An algorithm of adaptive polarization image fusion based on regional energy dynamic weighted average is proposed in this paper to combine these images. Through an experiment and simulations,most clutters are removed by this algorithm. The fusion method is used for different light conditions in simulation, and the influence of lighting conditions on the fusion results is analyzed.

  18. Induced Unbalanced Linguistic Ordered Weighted Average and Its Application in Multiperson Decision Making

    Directory of Open Access Journals (Sweden)

    Lucas Marin

    2014-01-01

    Full Text Available Linguistic variables are very useful to evaluate alternatives in decision making problems because they provide a vocabulary in natural language rather than numbers. Some aggregation operators for linguistic variables force the use of a symmetric and uniformly distributed set of terms. The need to relax these conditions has recently been posited. This paper presents the induced unbalanced linguistic ordered weighted average (IULOWA operator. This operator can deal with a set of unbalanced linguistic terms that are represented using fuzzy sets. We propose a new order-inducing criterion based on the specificity and fuzziness of the linguistic terms. Different relevancies are given to the fuzzy values according to their uncertainty degree. To illustrate the behaviour of the precision-based IULOWA operator, we present an environmental assessment case study in which a multiperson multicriteria decision making model is applied.

  19. Multi-criteria, personalized route planning using quantifier-guided ordered weighted averaging operators

    Science.gov (United States)

    Nadi, S.; Delavar, M. R.

    2011-06-01

    This paper presents a generic model for using different decision strategies in multi-criteria, personalized route planning. Some researchers have considered user preferences in navigation systems. However, these prior studies typically employed a high tradeoff decision strategy, which used a weighted linear aggregation rule, and neglected other decision strategies. The proposed model integrates a pairwise comparison method and quantifier-guided ordered weighted averaging (OWA) aggregation operators to form a personalized route planning method that incorporates different decision strategies. The model can be used to calculate the impedance of each link regarding user preferences in terms of the route criteria, criteria importance and the selected decision strategy. Regarding the decision strategy, the calculated impedance lies between aggregations that use a logical "and" (which requires all the criteria to be satisfied) and a logical "or" (which requires at least one criterion to be satisfied). The calculated impedance also includes taking the average of the criteria scores. The model results in multiple alternative routes, which apply different decision strategies and provide users with the flexibility to select one of them en-route based on the real world situation. The model also defines the robust personalized route under different decision strategies. The influence of different decision strategies on the results are investigated in an illustrative example. This model is implemented in a web-based geographical information system (GIS) for Isfahan in Iran and verified in a tourist routing scenario. The results demonstrated, in real world situations, the validity of the route planning carried out in the model.

  20. Modified Exponential Weighted Moving Average (EWMA) Control Chart on Autocorrelation Data

    Science.gov (United States)

    Herdiani, Erna Tri; Fandrilla, Geysa; Sunusi, Nurtiti

    2018-03-01

    In general, observations of the statistical process control are assumed to be mutually independence. However, this assumption is often violated in practice. Consequently, statistical process controls were developed for interrelated processes, including Shewhart, Cumulative Sum (CUSUM), and exponentially weighted moving average (EWMA) control charts in the data that were autocorrelation. One researcher stated that this chart is not suitable if the same control limits are used in the case of independent variables. For this reason, it is necessary to apply the time series model in building the control chart. A classical control chart for independent variables is usually applied to residual processes. This procedure is permitted provided that residuals are independent. In 1978, Shewhart modification for the autoregressive process was introduced by using the distance between the sample mean and the target value compared to the standard deviation of the autocorrelation process. In this paper we will examine the mean of EWMA for autocorrelation process derived from Montgomery and Patel. Performance to be investigated was investigated by examining Average Run Length (ARL) based on the Markov Chain Method.

  1. Studies concerning average volume flow and waterpacking anomalies in thermal-hydraulics codes

    International Nuclear Information System (INIS)

    Lyczkowski, R.W.; Ching, J.T.; Mecham, D.C.

    1977-01-01

    One-dimensional hydrodynamic codes have been observed to exhibit anomalous behavior in the form of non-physical pressure oscillations and spikes. It is our experience that sometimes this anomaloous behavior can result in mass depletion, steam table failure and in severe cases, problem abortion. In addition, these non-physical pressure spikes can result in long running times when small time steps are needed in an attempt to cope with anomalous solution behavior. The source of these pressure spikes has been conjectured to be caused by nonuniform enthalpy distribution or wave reflection off the closed end of a pipe or abrupt changes in pressure history when the fluid changes from subcooled to two-phase conditions. It is demonstrated in this paper that many of the faults can be attributed to inadequate modeling of the average volume flow and the sharp fluid density front crossing a junction. General corrective models are difficult to devise since the causes of the problems touch on the very theoretical bases of the differential field equations and associated solution scheme. For example, the fluid homogeneity assumption and the numerical extrapolation scheme have placed severe restrictions on the capability of a code to adequately model certain physical phenomena involving fluid discontinuities. The need for accurate junction and local properties to describe phenomena internal to a control volume often points to additional lengthy computations that are difficult to justify in terms of computational efficiency. Corrective models that are economical to implement and use are developed. When incorporated into the one-dimensional, homogeneous transient thermal-hydraulic analysis computer code, RELAP4, they help mitigate many of the code's difficulties related to average volume flow and water-packing anomalies. An average volume flow model and a critical density model are presented. Computational improvements due to these models are also demonstrated

  2. A stereotaxic, population-averaged T1w ovine brain atlas including cerebral morphology and tissue volumes

    Directory of Open Access Journals (Sweden)

    Björn eNitzsche

    2015-06-01

    Full Text Available Standard stereotaxic reference systems play a key role in human brain studies. Stereotaxic coordinate systems have also been developed for experimental animals including non-human primates, dogs and rodents. However, they are lacking for other species being relevant in experimental neuroscience including sheep. Here, we present a spatial, unbiased ovine brain template with tissue probability maps (TPM that offer a detailed stereotaxic reference frame for anatomical features and localization of brain areas, thereby enabling inter-individual and cross-study comparability. Three-dimensional data sets from healthy adult Merino sheep (Ovis orientalis aries, 12 ewes and 26 neutered rams were acquired on a 1.5T Philips MRI using a T1w sequence. Data were averaged by linear and non-linear registration algorithms. Moreover, animals were subjected to detailed brain volume analysis including examinations with respect to body weight, age and sex. The created T1w brain template provides an appropriate population-averaged ovine brain anatomy in a spatial standard coordinate system. Additionally, TPM for gray (GM and white (WM matter as well as cerebrospinal fluid (CSF classification enabled automatic prior-based tissue segmentation using statistical parametric mapping (SPM. Overall, a positive correlation of GM volume and body weight explained about 15% of the variance of GM while a positive correlation between WM and age was found. Absolute tissue volume differences were not detected, indeed ewes showed significantly more GM per bodyweight as compared to neutered rams. The created framework including spatial brain template and TPM represent a useful tool for unbiased automatic image preprocessing and morphological characterization in sheep. Therefore, the reported results may serve as a starting point for further experimental and/or translational research aiming at in vivo analysis in this species.

  3. The effect of above average weight gains on the incidence of radiographic bone aberrations and epiphysitis in growing horses

    International Nuclear Information System (INIS)

    Thompson, K.N.; Jackson, S.G.; Rooney, J.R.

    1988-01-01

    The relationship between body weight gain and the onset of bone aberrations (e.g. epiphysitis) is described. A model was derived which described the increase in transverse epiphyseal width, and the major factor found to affect epiphyseal width was average daily gain in body weight. In addition, a radiographic examination of the epiphyseal areas showed a larger number of bone aberrations in groups gaining weight at an above-average rate. Thus, a rapid increase in body weight can be suggested as a significant factor in the onset of epiphysitis

  4. Genome-Enabled Prediction of Breeding Values for Feedlot Average Daily Weight Gain in Nelore Cattle

    Directory of Open Access Journals (Sweden)

    Adriana L. Somavilla

    2017-06-01

    Full Text Available Nelore is the most economically important cattle breed in Brazil, and the use of genetically improved animals has contributed to increased beef production efficiency. The Brazilian beef feedlot industry has grown considerably in the last decade, so the selection of animals with higher growth rates on feedlot has become quite important. Genomic selection (GS could be used to reduce generation intervals and improve the rate of genetic gains. The aim of this study was to evaluate the prediction of genomic-estimated breeding values (GEBV for average daily weight gain (ADG in 718 feedlot-finished Nelore steers. Analyses of three Bayesian model specifications [Bayesian GBLUP (BGBLUP, BayesA, and BayesCπ] were performed with four genotype panels [Illumina BovineHD BeadChip, TagSNPs, and GeneSeek High- and Low-density indicus (HDi and LDi, respectively]. Estimates of Pearson correlations, regression coefficients, and mean squared errors were used to assess accuracy and bias of predictions. Overall, the BayesCπ model resulted in less biased predictions. Accuracies ranged from 0.18 to 0.27, which are reasonable values given the heritability estimates (from 0.40 to 0.44 and sample size (568 animals in the training population. Furthermore, results from Bos taurus indicus panels were as informative as those from Illumina BovineHD, indicating that they could be used to implement GS at lower costs.

  5. Estimating Loess Plateau Average Annual Precipitation with Multiple Linear Regression Kriging and Geographically Weighted Regression Kriging

    Directory of Open Access Journals (Sweden)

    Qiutong Jin

    2016-06-01

    Full Text Available Estimating the spatial distribution of precipitation is an important and challenging task in hydrology, climatology, ecology, and environmental science. In order to generate a highly accurate distribution map of average annual precipitation for the Loess Plateau in China, multiple linear regression Kriging (MLRK and geographically weighted regression Kriging (GWRK methods were employed using precipitation data from the period 1980–2010 from 435 meteorological stations. The predictors in regression Kriging were selected by stepwise regression analysis from many auxiliary environmental factors, such as elevation (DEM, normalized difference vegetation index (NDVI, solar radiation, slope, and aspect. All predictor distribution maps had a 500 m spatial resolution. Validation precipitation data from 130 hydrometeorological stations were used to assess the prediction accuracies of the MLRK and GWRK approaches. Results showed that both prediction maps with a 500 m spatial resolution interpolated by MLRK and GWRK had a high accuracy and captured detailed spatial distribution data; however, MLRK produced a lower prediction error and a higher variance explanation than GWRK, although the differences were small, in contrast to conclusions from similar studies.

  6. Angular finite volume method for solving the multigroup transport equation with piecewise average scattering cross sections

    Energy Technology Data Exchange (ETDEWEB)

    Calloo, A.; Vidal, J.F.; Le Tellier, R.; Rimpault, G., E-mail: ansar.calloo@cea.fr, E-mail: jean-francois.vidal@cea.fr, E-mail: romain.le-tellier@cea.fr, E-mail: gerald.rimpault@cea.fr [CEA, DEN, DER/SPRC/LEPh, Saint-Paul-lez-Durance (France)

    2011-07-01

    This paper deals with the solving of the multigroup integro-differential form of the transport equation for fine energy group structure. In that case, multigroup transfer cross sections display strongly peaked shape for light scatterers and the current Legendre polynomial expansion is not well-suited to represent them. Furthermore, even if considering an exact scattering cross sections representation, the scattering source in the discrete ordinates method (also known as the Sn method) being calculated by sampling the angular flux at given directions, may be wrongly computed due to lack of angular support for the angular flux. Hence, following the work of Gerts and Matthews, an angular finite volume solver has been developed for 2D Cartesian geometries. It integrates the multigroup transport equation over discrete volume elements obtained by meshing the unit sphere with a product grid over the polar and azimuthal coordinates and by considering the integrated flux per solid angle element. The convergence of this method has been compared to the S{sub n} method for a highly anisotropic benchmark. Besides, piecewise-average scattering cross sections have been produced for non-bound Hydrogen atoms using a free gas model for thermal neutrons. LWR lattice calculations comparing Legendre representations of the Hydrogen scattering multigroup cross section at various orders and piecewise-average cross sections for this same atom are carried out (while keeping a Legendre representation for all other isotopes). (author)

  7. Angular finite volume method for solving the multigroup transport equation with piecewise average scattering cross sections

    International Nuclear Information System (INIS)

    Calloo, A.; Vidal, J.F.; Le Tellier, R.; Rimpault, G.

    2011-01-01

    This paper deals with the solving of the multigroup integro-differential form of the transport equation for fine energy group structure. In that case, multigroup transfer cross sections display strongly peaked shape for light scatterers and the current Legendre polynomial expansion is not well-suited to represent them. Furthermore, even if considering an exact scattering cross sections representation, the scattering source in the discrete ordinates method (also known as the Sn method) being calculated by sampling the angular flux at given directions, may be wrongly computed due to lack of angular support for the angular flux. Hence, following the work of Gerts and Matthews, an angular finite volume solver has been developed for 2D Cartesian geometries. It integrates the multigroup transport equation over discrete volume elements obtained by meshing the unit sphere with a product grid over the polar and azimuthal coordinates and by considering the integrated flux per solid angle element. The convergence of this method has been compared to the S_n method for a highly anisotropic benchmark. Besides, piecewise-average scattering cross sections have been produced for non-bound Hydrogen atoms using a free gas model for thermal neutrons. LWR lattice calculations comparing Legendre representations of the Hydrogen scattering multigroup cross section at various orders and piecewise-average cross sections for this same atom are carried out (while keeping a Legendre representation for all other isotopes). (author)

  8. SENSITIVITY ANALYSIS OF ORDERED WEIGHTED AVERAGING OPERATOR IN EARTHQUAKE VULNERABILITY ASSESSMENT

    Directory of Open Access Journals (Sweden)

    M. Moradi

    2013-09-01

    Full Text Available The main objective of this research is to find the extent to which the minimal variability Ordered Weighted Averaging (OWA model of seismic vulnerability assessment is sensitive to variation of optimism degree. There are a variety of models proposed for seismic vulnerability assessment. In order to examine the efficiency of seismic vulnerability assessment models, the stability of results could be analysed. Seismic vulnerability assessment is done to estimate the probable losses in the future earthquake. Multi-Criteria Decision Making (MCDM methods have been applied by a number of researchers to estimate the human, physical and financial losses in urban areas. The study area of this research is Tehran Metropolitan Area (TMA which has more than eight million inhabitants. In addition, this paper assumes that North Tehran Fault (NTF is activated and caused an earthquake in TMA. 1996 census data is used to extract the attribute values for six effective criteria in seismic vulnerability assessment. The results demonstrate that minimal variability OWA model of Seismic Loss Estimation (SLE is more stable where the aggregated seismic vulnerability degree has a lower value. Moreover, minimal variability OWA is very sensitive to optimism degree in northern areas of Tehran. A number of statistical units in southern areas of the city also indicate considerable sensitivity to optimism degree due to numerous non-standard buildings. In addition, the change of seismic vulnerability degree caused by variation of optimism degree does not exceed 25 % of the original value which means that the overall accuracy of the model is acceptable.

  9. PREPARATION OF ULTRA-LOW VOLUME WEIGHT AUTOCLAVED AERATED CONCRETE

    Directory of Open Access Journals (Sweden)

    Ondrej Koutny

    2016-12-01

    Full Text Available Autoclaved aerated concrete is a modern construction material that gains its popularity especially due to its thermal insulation performance resulting from low volume weight and porous structure with sufficient mechanical strength. Nowadays, there are attempts to use this material for thermal insulation purposes and to replace current systems, which have many disadvantages, mainly concerning durability. The key for improvement of thermal insulation properties is therefore obtaining a material based on autoclaved aerated concrete with extremely low volume weight (below 200 kg/m ³ ensuring good thermal isolation properties, but with sufficient mechanical properties to allow easy manipulation. This material can be prepared by foaming very fine powder materials such as silica fume or very finely ground sand. This paper deals with the possibilities of preparation and summarizes the basic requirements for successful preparation of such a material.

  10. Homogenization via formal multiscale asymptotics and volume averaging: How do the two techniques compare?

    KAUST Repository

    Davit, Yohan

    2013-12-01

    A wide variety of techniques have been developed to homogenize transport equations in multiscale and multiphase systems. This has yielded a rich and diverse field, but has also resulted in the emergence of isolated scientific communities and disconnected bodies of literature. Here, our goal is to bridge the gap between formal multiscale asymptotics and the volume averaging theory. We illustrate the methodologies via a simple example application describing a parabolic transport problem and, in so doing, compare their respective advantages/disadvantages from a practical point of view. This paper is also intended as a pedagogical guide and may be viewed as a tutorial for graduate students as we provide historical context, detail subtle points with great care, and reference many fundamental works. © 2013 Elsevier Ltd.

  11. Measurement of average density and relative volumes in a dispersed two-phase fluid

    Science.gov (United States)

    Sreepada, Sastry R.; Rippel, Robert R.

    1992-01-01

    An apparatus and a method are disclosed for measuring the average density and relative volumes in an essentially transparent, dispersed two-phase fluid. A laser beam with a diameter no greater than 1% of the diameter of the bubbles, droplets, or particles of the dispersed phase is directed onto a diffraction grating. A single-order component of the diffracted beam is directed through the two-phase fluid and its refraction is measured. Preferably, the refracted beam exiting the fluid is incident upon a optical filter with linearly varing optical density and the intensity of the filtered beam is measured. The invention can be combined with other laser-based measurement systems, e.g., laser doppler anemometry.

  12. The effect of temperature on the average volume of Barkhausen jump on Q235 carbon steel

    Science.gov (United States)

    Guo, Lei; Shu, Di; Yin, Liang; Chen, Juan; Qi, Xin

    2016-06-01

    On the basis of the average volume of Barkhausen jump (AVBJ) vbar generated by irreversible displacement of magnetic domain wall under the effect of the incentive magnetic field on ferromagnetic materials, the functional relationship between saturation magnetization Ms and temperature T is employed in this paper to deduce the explicit mathematical expression among AVBJ vbar, stress σ, incentive magnetic field H and temperature T. Then the change law between AVBJ vbar and temperature T is researched according to the mathematical expression. Moreover, the tensile and compressive stress experiments are carried out on Q235 carbon steel specimens at different temperature to verify our theories. This paper offers a series of theoretical bases to solve the temperature compensation problem of Barkhausen testing method.

  13. Evaluation of scission and crosslinking yields in γ-irradiated poly(acrylic acid) and poly(methacrylic acid) from weight- and Ζ-average molecular weights determined by sedimentation equilibrium

    International Nuclear Information System (INIS)

    Hill, D.J.T.; O'Donnell, J.H.; Winzor, C.L.; Winzor, D.J.

    1990-01-01

    Weight- and Ζ-average molecular weights, M-bar W (D) and M-bar Ζ (D), of poly(methacrylic acid) (PMMA) and poly(acrylic acid) (PAA) have been determined by sedimentation equilibrium in the ultracentrifuge after various doses D of γ-radiation in vacuum. Relationships between [M i (0)/M i (D)-1]/D and D (i=w or Ζ), derived recently by O'Donnell and coworkers, have been used to determine radiation chemical yields for scission and crosslinking of G(S)=6.0, G(X)=0 for PMAA and G(S)=0, G(X)=0.44 for PAA. Allowance was necessary for the effects of COOH decomposition on the average values of the molecular weight and partial specific volume for irradiated PAA. (author)

  14. Forecast Accuracy and Economic Gains from Bayesian Model Averaging using Time Varying Weights

    NARCIS (Netherlands)

    L.F. Hoogerheide (Lennart); R.H. Kleijn (Richard); H.K. van Dijk (Herman); M.J.C.M. Verbeek (Marno)

    2009-01-01

    textabstractSeveral Bayesian model combination schemes, including some novel approaches that simultaneously allow for parameter uncertainty, model uncertainty and robust time varying model weights, are compared in terms of forecast accuracy and economic gains using financial and macroeconomic time

  15. A system dynamics optimization framework to achieve population desired of average weight target

    Science.gov (United States)

    Abidin, Norhaslinda Zainal; Zulkepli, Jafri Haji; Zaibidi, Nerda Zura

    2017-11-01

    Obesity is becoming a serious problem in Malaysia as it has been rated as the highest among Asian countries. The aim of the paper is to propose a system dynamics (SD) optimization framework to achieve population desired weight target based on the changes in physical activity behavior and its association to weight and obesity. The system dynamics approach of stocks and flows diagram was used to quantitatively model the impact of both behavior on the population's weight and obesity trends. This work seems to bring this idea together and highlighting the interdependence of the various aspects of eating and physical activity behavior on the complex of human weight regulation system. The model was used as an experimentation vehicle to investigate the impacts of changes in physical activity on weight and prevalence of obesity implications. This framework paper provides evidence on the usefulness of SD optimization as a strategic decision making approach to assist in decision making related to obesity prevention. SD applied in this research is relatively new in Malaysia and has a high potential to apply to any feedback models that address the behavior cause to obesity.

  16. Baseline Gray- and White Matter Volume Predict Successful Weight Loss in the Elderly

    Science.gov (United States)

    Mokhtari, Fatemeh; Paolini, Brielle M.; Burdette, Jonathan H.; Marsh, Anthony P.; Rejeski, W. Jack; Laurienti, Paul J.

    2016-01-01

    Objective The purpose of this study is to investigate if structural brain phenotypes can be used to predict weight loss success following behavioral interventions in older adults that are overweight or obese and have cardiometabolic dysfunction. Methods A support vector machine (SVM) with a repeated random subsampling validation approach was used to classify participants into the upper and lower halves of the weight loss distribution following 18 months of a weight loss intervention. Predictions were based on baseline brain gray matter (GM) and white matter (WM) volume from 52 individuals that completed the intervention and a magnetic resonance imaging session. Results The SVM resulted in an average classification accuracy of 72.62 % based on GM and WM volume. A receiver operating characteristic analysis indicated that classification performance was robust based on an area under the curve of 0.82. Conclusions Our findings suggest that baseline brain structure is able to predict weight loss success following 18 months of treatment. The identification of brain structure as a predictor of successful weight loss is an innovative approach to identifying phenotypes for responsiveness to intensive lifestyle interventions. This phenotype could prove useful in future research focusing on the tailoring of treatment for weight loss. PMID:27804273

  17. 77 FR 8101 - Antidumping Proceedings: Calculation of the Weighted-Average Dumping Margin and Assessment Rate...

    Science.gov (United States)

    2012-02-14

    ...), US--Zeroing (Japan), US--Stainless Steel (Mexico), and US--Continued Zeroing (EC) found the denial of... comparisons between transaction-specific export prices and average normal values and does not offset the amount of dumping that is found with the results of comparisons for which the transaction-specific export...

  18. "Whatever average is:" understanding African-American mothers' perceptions of infant weight, growth, and health.

    Science.gov (United States)

    Thompson, Amanda L; Adair, Linda; Bentley, Margaret E

    2014-06-01

    Biomedical researchers have raised concerns that mothers' inability to recognize infant and toddler overweight poses a barrier to stemming increasing rates of overweight and obesity, particularly among low-income or minority mothers. Little anthropological research has examined the sociocultural, economic or structural factors shaping maternal perceptions of infant and toddler size or addressed biomedical depictions of maternal misperception as a "socio-cultural problem." We use qualitative and quantitative data from 237 low-income, African-American mothers to explore how they define 'normal' infant growth and infant overweight. Our quantitative results document that mothers' perceptions of infant size change with infant age, are sensitive to the size of other infants in the community, and are associated with concerns over health and appetite. Qualitative analysis documents that mothers are concerned with their children's weight status and assess size in relation to their infants' cues, local and societal norms of appropriate size, interactions with biomedicine, and concerns about infant health and sufficiency. These findings suggest that mothers use multiple models to interpret and respond to child weight. An anthropological focus on the complex social and structural factors shaping what is considered 'normal' and 'abnormal' infant weight is critical for shaping appropriate and successful interventions.

  19. Instantaneous equations for multiphase flow in porous media without length-scale restrictions using a non-local averaging volume

    International Nuclear Information System (INIS)

    Espinosa-Paredes, Gilberto

    2010-01-01

    The aim of this paper is to propose a framework to obtain a new formulation for multiphase flow conservation equations without length-scale restrictions, based on the non-local form of the averaged volume conservation equations. The simplification of the local averaging volume of the conservation equations to obtain practical equations is subject to the following length-scale restrictions: d << l << L, where d is the characteristic length of the dispersed phases, l is the characteristic length of the averaging volume, and L is the characteristic length of the physical system. If the foregoing inequality does not hold, or if the scale of the problem of interest is of the order of l, the averaging technique and therefore, the macroscopic theories of multiphase flow should be modified in order to include appropriate considerations and terms in the corresponding equations. In these cases the local form of the averaged volume conservation equations are not appropriate to describe the multiphase system. As an example of the conservation equations without length-scale restrictions, the natural circulation boiling water reactor was consider to study the non-local effects on the thermal-hydraulic core performance during steady-state and transient behaviors, and the results were compared with the classic local averaging volume conservation equations.

  20. Composite indicators for security of energy supply using ordered weighted averaging

    International Nuclear Information System (INIS)

    Costescu Badea, Anca; Rocco S, Claudio M.; Tarantola, Stefano; Bolado, Ricardo

    2011-01-01

    In this paper we propose to use an aggregation rule derived from the Group Decision Theory, and based on the ranks of a set of individual indicators, for building a family of composite indicators for the security of energy supply. This family of composite indicators depends on a parameter associated with the risk-averse level of the decision maker, which can hence vary continuously from risk-prone to risk-averse. It represents a valuable and objective instrument to evaluate the degree of security of energy supply of different countries without entering into controversial matters related to the choice of the weights. This methodology can be used to aggregate either ranks or normalized values of the individual indicators. We apply it to a set of individual indicators, accounting for different dimensions of the security of supply and derived from the outputs of an energy system model. We study the evolution in time of the countries' performances, as well as the propagation of the uncertainties associated with the individual indicators to the composite. We also studied the robustness of such composite indicators with respect to the risk-averse level.

  1. Averages, Areas and Volumes; Cambridge Conference on School Mathematics Feasibility Study No. 45.

    Science.gov (United States)

    Cambridge Conference on School Mathematics, Newton, MA.

    Presented is an elementary approach to areas, columns and other mathematical concepts usually treated in calculus. The approach is based on the idea of average and this concept is utilized throughout the report. In the beginning the average (arithmetic mean) of a set of numbers is considered and two properties of the average which often simplify…

  2. Analysis and Design of Improved Weighted Average Current Control Strategy for LCL-Type Grid-Connected Inverters

    DEFF Research Database (Denmark)

    Han, Yang; Li, Zipeng; Yang, Ping

    2017-01-01

    The LCL grid-connected inverter has the ability to attenuate the high-frequency current harmonics. However, the inherent resonance of the LCL filter affects the system stability significantly. To damp the resonance effect, the dual-loop current control can be used to stabilize the system. The grid...... Control Strategy for LCL-Type Grid-Connected Inverters. Available from: https://www.researchgate.net/publication/313734269_Analysis_and_Design_of_Improved_Weighted_Average_Current_Control_Strategy_for_LCL-Type_Grid-Connected_Inverters [accessed Apr 20, 2017]....... current plus capacitor current feedback system is widely used for its better transient response and high robustness against the grid impedance variations. While the weighted average current (WAC) feedback scheme is capable to provide a wider bandwidth at higher frequencies but show poor stability...

  3. Percentiles of the run-length distribution of the Exponentially Weighted Moving Average (EWMA) median chart

    Science.gov (United States)

    Tan, K. L.; Chong, Z. L.; Khoo, M. B. C.; Teoh, W. L.; Teh, S. Y.

    2017-09-01

    Quality control is crucial in a wide variety of fields, as it can help to satisfy customers’ needs and requirements by enhancing and improving the products and services to a superior quality level. The EWMA median chart was proposed as a useful alternative to the EWMA \\bar{X} chart because the median-type chart is robust against contamination, outliers or small deviation from the normality assumption compared to the traditional \\bar{X}-type chart. To provide a complete understanding of the run-length distribution, the percentiles of the run-length distribution should be investigated rather than depending solely on the average run length (ARL) performance measure. This is because interpretation depending on the ARL alone can be misleading, as the process mean shifts change according to the skewness and shape of the run-length distribution, varying from almost symmetric when the magnitude of the mean shift is large, to highly right-skewed when the process is in-control (IC) or slightly out-of-control (OOC). Before computing the percentiles of the run-length distribution, optimal parameters of the EWMA median chart will be obtained by minimizing the OOC ARL, while retaining the IC ARL at a desired value.

  4. SACALCCYL, Calculates the average solid angle subtended by a volume; SACALC2B, Calculates the average solid angle for source-detector geometries

    International Nuclear Information System (INIS)

    Whitcher, Ralph

    2007-01-01

    1 - Description of program or function: SACALC2B calculates the average solid angle subtended by a rectangular or circular detector window to a coaxial or non-coaxial rectangular, circular or point source, including where the source and detector planes are not parallel. SACALC C YL calculates the average solid angle subtended by a cylinder to a rectangular or circular source, plane or thick, at any location and orientation. This is needed, for example, in calculating the intrinsic gamma efficiency of a detector such as a GM tube. The program also calculates the number of hits on the cylinder side and on each end, and the average path length through the detector volume (assuming no scattering or absorption). Point sources can be modelled by using a circular source of zero radius. NEA-1688/03: Documentation has been updated (January 2006). 2 - Methods: The program uses a Monte Carlo method to calculate average solid angle for source-detector geometries that are difficult to analyse by analytical methods. The values of solid angle are calculated to accuracies of typically better than 0.1%. The calculated values from the Monte Carlo method agree closely with those produced by polygon approximation and numerical integration by Gardner and Verghese, and others. 3 - Restrictions on the complexity of the problem: The program models a circular or rectangular detector in planes that are not necessarily coaxial, nor parallel. Point sources can be modelled by using a circular source of zero radius. The sources are assumed to be uniformly distributed. NEA-1688/04: In SACALC C YL, to avoid rounding errors, differences less than 1 E-12 are assumed to be zero

  5. Long-Term Prediction of Emergency Department Revenue and Visitor Volume Using Autoregressive Integrated Moving Average Model

    Directory of Open Access Journals (Sweden)

    Chieh-Fan Chen

    2011-01-01

    Full Text Available This study analyzed meteorological, clinical and economic factors in terms of their effects on monthly ED revenue and visitor volume. Monthly data from January 1, 2005 to September 30, 2009 were analyzed. Spearman correlation and cross-correlation analyses were performed to identify the correlation between each independent variable, ED revenue, and visitor volume. Autoregressive integrated moving average (ARIMA model was used to quantify the relationship between each independent variable, ED revenue, and visitor volume. The accuracies were evaluated by comparing model forecasts to actual values with mean absolute percentage of error. Sensitivity of prediction errors to model training time was also evaluated. The ARIMA models indicated that mean maximum temperature, relative humidity, rainfall, non-trauma, and trauma visits may correlate positively with ED revenue, but mean minimum temperature may correlate negatively with ED revenue. Moreover, mean minimum temperature and stock market index fluctuation may correlate positively with trauma visitor volume. Mean maximum temperature, relative humidity and stock market index fluctuation may correlate positively with non-trauma visitor volume. Mean maximum temperature and relative humidity may correlate positively with pediatric visitor volume, but mean minimum temperature may correlate negatively with pediatric visitor volume. The model also performed well in forecasting revenue and visitor volume.

  6. New Internet search volume-based weighting method for integrating various environmental impacts

    Energy Technology Data Exchange (ETDEWEB)

    Ji, Changyoon, E-mail: changyoon@yonsei.ac.kr; Hong, Taehoon, E-mail: hong7@yonsei.ac.kr

    2016-01-15

    Weighting is one of the steps in life cycle impact assessment that integrates various characterized environmental impacts as a single index. Weighting factors should be based on the society's preferences. However, most previous studies consider only the opinion of some people. Thus, this research proposes a new weighting method that determines the weighting factors of environmental impact categories by considering public opinion on environmental impacts using the Internet search volumes for relevant terms. To validate the new weighting method, the weighting factors for six environmental impacts calculated by the new weighting method were compared with the existing weighting factors. The resulting Pearson's correlation coefficient between the new and existing weighting factors was from 0.8743 to 0.9889. It turned out that the new weighting method presents reasonable weighting factors. It also requires less time and lower cost compared to existing methods and likewise meets the main requirements of weighting methods such as simplicity, transparency, and reproducibility. The new weighting method is expected to be a good alternative for determining the weighting factor. - Highlight: • A new weighting method using Internet search volume is proposed in this research. • The new weighting method reflects the public opinion using Internet search volume. • The correlation coefficient between new and existing weighting factors is over 0.87. • The new weighting method can present the reasonable weighting factors. • The proposed method can be a good alternative for determining the weighting factors.

  7. New Internet search volume-based weighting method for integrating various environmental impacts

    International Nuclear Information System (INIS)

    Ji, Changyoon; Hong, Taehoon

    2016-01-01

    Weighting is one of the steps in life cycle impact assessment that integrates various characterized environmental impacts as a single index. Weighting factors should be based on the society's preferences. However, most previous studies consider only the opinion of some people. Thus, this research proposes a new weighting method that determines the weighting factors of environmental impact categories by considering public opinion on environmental impacts using the Internet search volumes for relevant terms. To validate the new weighting method, the weighting factors for six environmental impacts calculated by the new weighting method were compared with the existing weighting factors. The resulting Pearson's correlation coefficient between the new and existing weighting factors was from 0.8743 to 0.9889. It turned out that the new weighting method presents reasonable weighting factors. It also requires less time and lower cost compared to existing methods and likewise meets the main requirements of weighting methods such as simplicity, transparency, and reproducibility. The new weighting method is expected to be a good alternative for determining the weighting factor. - Highlight: • A new weighting method using Internet search volume is proposed in this research. • The new weighting method reflects the public opinion using Internet search volume. • The correlation coefficient between new and existing weighting factors is over 0.87. • The new weighting method can present the reasonable weighting factors. • The proposed method can be a good alternative for determining the weighting factors.

  8. Modelling lidar volume-averaging and its significance to wind turbine wake measurements

    DEFF Research Database (Denmark)

    Meyer Forsting, Alexander Raul; Troldborg, Niels; Borraccino, Antoine

    2017-01-01

    gradients, like the rotor wake, can it be detrimental. Hence, an efficient algorithm mimicking lidar flow sampling is presented, which considers both pulsed and continous-wave lidar weighting functions. The flow-field around a 2.3 MW turbine is simulated using Detached Eddy Simulation in combination...

  9. MR renography : An algorithm for calculation and correction of cortical volume averaging in medullary renographs

    NARCIS (Netherlands)

    de Priester, JA; den Boer, JA; Giele, ELW; Christiaans, MHL; Kessels, A; Hasman, A; van Engelshoven, JMA

    We evaluated a mathematical algorithm for the generation of medullary signal from raw dynamic magnetic resonance (MR) data. Five healthy volunteers were studied. MR examination consisted of a run of 100 TI-weighted coronal scans (gradient echo: TR/TE 11/3.4 msec, flip angle 60 degrees; slice

  10. NMR measurement of dynamic nuclear polarization: a technique to test the quality of its volume average obtained with different NMR coil configurations

    International Nuclear Information System (INIS)

    Zhao, W.H.; Cox, S.F.J.

    1980-07-01

    In the NMR measurement of dynamic nuclear polarization, a volume average is obtained where the contribution from different parts of the sample is weighted according to the local intensity of the RF field component perpendicular to the large static field. A method of mapping this quantity is described. A small metallic object whose geometry is chosen to perturb the appropriate RF component is scanned through the region to be occupied by the sample. The response of the phase angle of the impedance of a tuned circuit comprising the NMR coil gives a direct measurement of the local weighting factor. The correlation between theory and experiment was obtained by using a circular coil. The measuring method, checked in this way, was then used to investigate the field profiles of practical coils which are required to be rectangular for a proposed experimental neutron polarizing filter. This method can be used to evaluate other practical RF coils. (author)

  11. Non-invasive assessment of distribution volume ratios and binding potential: tissue heterogeneity and interindividually averaged time-activity curves

    Energy Technology Data Exchange (ETDEWEB)

    Reimold, M.; Mueller-Schauenburg, W.; Dohmen, B.M.; Bares, R. [Department of Nuclear Medicine, University of Tuebingen, Otfried-Mueller-Strasse 14, 72076, Tuebingen (Germany); Becker, G.A. [Nuclear Medicine, University of Leipzig, Leipzig (Germany); Reischl, G. [Radiopharmacy, University of Tuebingen, Tuebingen (Germany)

    2004-04-01

    Due to the stochastic nature of radioactive decay, any measurement of radioactivity concentration requires spatial averaging. In pharmacokinetic analysis of time-activity curves (TAC), such averaging over heterogeneous tissues may introduce a systematic error (heterogeneity error) but may also improve the accuracy and precision of parameter estimation. In addition to spatial averaging (inevitable due to limited scanner resolution and intended in ROI analysis), interindividual averaging may theoretically be beneficial, too. The aim of this study was to investigate the effect of such averaging on the binding potential (BP) calculated with Logan's non-invasive graphical analysis and the ''simplified reference tissue method'' (SRTM) proposed by Lammertsma and Hume, on the basis of simulated and measured positron emission tomography data [{sup 11}C]d-threo-methylphenidate (dMP) and [{sup 11}C]raclopride (RAC) PET. dMP was not quantified with SRTM since the low k {sub 2} (washout rate constant from the first tissue compartment) introduced a high noise sensitivity. Even for considerably different shapes of TAC (dMP PET in parkinsonian patients and healthy controls, [{sup 11}C]raclopride in patients with and without haloperidol medication) and a high variance in the rate constants (e.g. simulated standard deviation of K {sub 1}=25%), the BP obtained from average TAC was close to the mean BP (<5%). However, unfavourably distributed parameters, especially a correlated large variance in two or more parameters, may lead to larger errors. In Monte Carlo simulations, interindividual averaging before quantification reduced the variance from the SRTM (beyond a critical signal to noise ratio) and the bias in Logan's method. Interindividual averaging may further increase accuracy when there is an error term in the reference tissue assumption E=DV {sub 2}-DV ' (DV {sub 2} = distribution volume of the first tissue compartment, DV &apos

  12. Electrical method for the measurements of volume averaged electron density and effective coupled power to the plasma bulk

    Science.gov (United States)

    Henault, M.; Wattieaux, G.; Lecas, T.; Renouard, J. P.; Boufendi, L.

    2016-02-01

    Nanoparticles growing or injected in a low pressure cold plasma generated by a radiofrequency capacitively coupled capacitive discharge induce strong modifications in the electrical parameters of both plasma and discharge. In this paper, a non-intrusive method, based on the measurement of the plasma impedance, is used to determine the volume averaged electron density and effective coupled power to the plasma bulk. Good agreements are found when the results are compared to those given by other well-known and established methods.

  13. RESEARCH ON WEIGHT EVOLUTION AND DAILY AVERAGE INCREASE TO FOUR DIFFERENT GROUPS OF LITTLE CROSSBREED BULLS EXPOSED TO INTENSIVE FATTENING

    Directory of Open Access Journals (Sweden)

    I.R. MOLDOVAN

    2009-10-01

    Full Text Available Research aimed to highlight the weight differences and daily growth average of four groups of little crossbreed bulls raised in the same environmental conditions and having the same feeding diet. Farm in which they do research is TCE 3 abis SRL Piatra Neamt, located in Zanesti village at 14 km from the city of Piatra Neamt. Location of the farm is on the old IAS Zanesti and is endowed eight shelters from which two are still functional. Shelters are divided into collective lumber rooms, on which are housed an optimal number of calves depending on their age, number varied from 25 calves at 0 - 3 months up to 6 heads during growing and finishing period when they reach weights of 600-700 kg. Farm population is obtained with calves from reformed cows from milk farm belonging to the same company. Forage base is provided from the company's vegetable farm, farm exploits about 14,000 ha of arable land in Neamt County. Feeding (in three phases is made with the technological trailer once-daily in morning and drinking is made at discretion at constant.

  14. The disk averaged star formation relation for Local Volume dwarf galaxies

    Science.gov (United States)

    López-Sánchez, Á. R.; Lagos, C. D. P.; Young, T.; Jerjen, H.

    2018-05-01

    Spatially resolved H I studies of dwarf galaxies have provided a wealth of precision data. However these high-quality, resolved observations are only possible for handful of dwarf galaxies in the Local Volume. Future H I surveys are unlikely to improve the current situation. We therefore explore a method for estimating the surface density of the atomic gas from global H I parameters, which are conversely widely available. We perform empirical tests using galaxies with resolved H I maps, and find that our approximation produces values for the surface density of atomic hydrogen within typically 0.5 dex of the true value. We apply this method to a sample of 147 galaxies drawn from modern near-infrared stellar photometric surveys. With this sample we confirm a strict correlation between the atomic gas surface density and the star formation rate surface density, that is vertically offset from the Kennicutt-Schmidt relation by a factor of 10 - 30, and significantly steeper than the classical N = 1.4 of Kennicutt (1998). We further infer the molecular fraction in the sample of low surface brightness, predominantly dwarf galaxies by assuming that the star formation relationship with molecular gas observed for spiral galaxies also holds in these galaxies, finding a molecular-to-atomic gas mass fraction within the range of 5-15%. Comparison of the data to available models shows that a model in which the thermal pressure balances the vertical gravitational field captures better the shape of the ΣSFR-Σgas relationship. However, such models fail to reproduce the data completely, suggesting that thermal pressure plays an important role in the disks of dwarf galaxies.

  15. Inverse optimization of objective function weights for treatment planning using clinical dose-volume histograms

    Science.gov (United States)

    Babier, Aaron; Boutilier, Justin J.; Sharpe, Michael B.; McNiven, Andrea L.; Chan, Timothy C. Y.

    2018-05-01

    We developed and evaluated a novel inverse optimization (IO) model to estimate objective function weights from clinical dose-volume histograms (DVHs). These weights were used to solve a treatment planning problem to generate ‘inverse plans’ that had similar DVHs to the original clinical DVHs. Our methodology was applied to 217 clinical head and neck cancer treatment plans that were previously delivered at Princess Margaret Cancer Centre in Canada. Inverse plan DVHs were compared to the clinical DVHs using objective function values, dose-volume differences, and frequency of clinical planning criteria satisfaction. Median differences between the clinical and inverse DVHs were within 1.1 Gy. For most structures, the difference in clinical planning criteria satisfaction between the clinical and inverse plans was at most 1.4%. For structures where the two plans differed by more than 1.4% in planning criteria satisfaction, the difference in average criterion violation was less than 0.5 Gy. Overall, the inverse plans were very similar to the clinical plans. Compared with a previous inverse optimization method from the literature, our new inverse plans typically satisfied the same or more clinical criteria, and had consistently lower fluence heterogeneity. Overall, this paper demonstrates that DVHs, which are essentially summary statistics, provide sufficient information to estimate objective function weights that result in high quality treatment plans. However, as with any summary statistic that compresses three-dimensional dose information, care must be taken to avoid generating plans with undesirable features such as hotspots; our computational results suggest that such undesirable spatial features were uncommon. Our IO-based approach can be integrated into the current clinical planning paradigm to better initialize the planning process and improve planning efficiency. It could also be embedded in a knowledge-based planning or adaptive radiation therapy framework to

  16. Market value calculation and the solution of circularity between value and the weighted average cost of capital WACC

    Directory of Open Access Journals (Sweden)

    Ignacio Vélez-Pareja

    2009-12-01

    Full Text Available Most finance textbooks present the Weighted Average Cost of Capital (WACC calculation as: WACC = Kd×(1-T×D% + Ke×E%, where Kd is the cost of debt before taxes, T is the tax rate, D% is the percentage of debt on total value, Ke is the cost of equity and E% is the percentage of equity on total value. All of them precise (but not with enough emphasis that the values to calculate D% y E% are market values. Although they devote special space and thought to calculate Kd and Ke, little effort is made to the correct calculation of market values. This means that there are several points that are not sufficiently dealt with: Market values, location in time, occurrence of tax payments, WACC changes in time and the circularity in calculating WACC. The purpose of this note is to clear up these ideas, solve the circularity problem and emphasize in some ideas that usually are looked over. Also, some suggestions are presented on how to calculate, or estimate, the equity cost of capital.

  17. The influence of poly(acrylic) acid number average molecular weight and concentration in solution on the compressive fracture strength and modulus of a glass-ionomer restorative.

    LENUS (Irish Health Repository)

    Dowling, Adam H

    2011-06-01

    The aim was to investigate the influence of number average molecular weight and concentration of the poly(acrylic) acid (PAA) liquid constituent of a GI restorative on the compressive fracture strength (σ) and modulus (E).

  18. Weight and volume estimates for aluminum-air batteries designed for electric vehicle applications

    Science.gov (United States)

    Cooper, J. F.

    1980-01-01

    The weights and volumes of reactants, electrolyte, and hardware components are estimated for an aluminum-air battery designed for a 40-kW (peak), 70-kWh aluminum-air battery. Generalized equations are derived which express battery power and energy content as functions of total anode area, aluminum-anode weight, and discharge current density. Equations are also presented which express total battery weight and volume as linear combinations of the variables, anode area and anode weight. The sizing and placement of battery components within the engine compartment of typical five-passenger vehicles is briefly discussed.

  19. A randomised clinical trial on the efficacy of oxytetracycline dose through water medication of nursery pigs on diarrhoea, faecal shedding of Lawsonia intracellularis and average daily weight gain

    DEFF Research Database (Denmark)

    Larsen, Inge-Lise; Hjulsager, Charlotte Kristiane; Holm, Anders

    2016-01-01

    the efficacy of three oral dosage regimens (5, 10 and 20mg/kg body weight) of oxytetracycline (OTC) in drinking water over a five-day period on diarrhoea, faecal shedding of LI and average daily weight gain (ADG). A randomised clinical trial was carried out in four Danish pig herds. In total, 539 animals from...

  20. Three-dimensional computed tomographic angiography to predict weight and volume of deep inferior epigastric artery perforator flap for breast reconstruction.

    Science.gov (United States)

    Rosson, Gedge D; Shridharani, Sachin M; Magarakis, Michael; Manahan, Michele A; Stapleton, Sahael M; Gilson, Marta M; Flores, Jaime I; Basdag, Basak; Fishman, Elliot K

    2011-10-01

    Three-dimensional computed tomographic angiography (3D CTA) can be used preoperatively to evaluate the course and caliber of perforating blood vessels for abdominal free-flap breast reconstruction. For postmastectomy breast reconstruction, many women inquire whether the abdominal tissue volume will match that of the breast to be removed. Therefore, our goal was to estimate preoperative volume and weight of the proposed flap and compare them with the actual volume and weight to determine if diagnostic imaging can accurately identify the amount of tissue that could potentially to be harvested. Preoperative 3D CTA was performed in 15 patients, who underwent breast reconstruction using the deep inferior epigastric artery perforator flap. Before each angiogram, stereotactic fiducials were placed on the planned flap outline. The radiologist reviewed each preoperative angiogram to estimate the volume, and thus, weight of the flap. These estimated weights were compared with the actual intraoperative weights. The average estimated weight was 99.7% of the actual weight. The interquartile range (25th to 75th percentile), which represents the "middle half" of the patients, was 91-109%, indicating that half of the patients had an estimated weight within 9% of the actual weight; however, there was a large range (70-133%). 3D CTA with stereotactic fiducials allows surgeons to adequately estimate abdominal flap volume before surgery, potentially giving guidance in the amount of tissue that can be harvested from a patient's lower abdomen. Copyright © 2011 Wiley-Liss, Inc.

  1. Comparison of Spot and Time Weighted Averaging (TWA Sampling with SPME-GC/MS Methods for Trihalomethane (THM Analysis

    Directory of Open Access Journals (Sweden)

    Don-Roger Parkinson

    2016-02-01

    Full Text Available Water samples were collected and analyzed for conductivity, pH, temperature and trihalomethanes (THMs during the fall of 2014 at two monitored municipal drinking water source ponds. Both spot (or grab and time weighted average (TWA sampling methods were assessed over the same two day sampling time period. For spot sampling, replicate samples were taken at each site and analyzed within 12 h of sampling by both Headspace (HS- and direct (DI- solid phase microextraction (SPME sampling/extraction methods followed by Gas Chromatography/Mass Spectrometry (GC/MS. For TWA, a two day passive on-site TWA sampling was carried out at the same sampling points in the ponds. All SPME sampling methods undertaken used a 65-µm PDMS/DVB SPME fiber, which was found optimal for THM sampling. Sampling conditions were optimized in the laboratory using calibration standards of chloroform, bromoform, bromodichloromethane, dibromochloromethane, 1,2-dibromoethane and 1,2-dichloroethane, prepared in aqueous solutions from analytical grade samples. Calibration curves for all methods with R2 values ranging from 0.985–0.998 (N = 5 over the quantitation linear range of 3–800 ppb were achieved. The different sampling methods were compared for quantification of the water samples, and results showed that DI- and TWA- sampling methods gave better data and analytical metrics. Addition of 10% wt./vol. of (NH42SO4 salt to the sampling vial was found to aid extraction of THMs by increasing GC peaks areas by about 10%, which resulted in lower detection limits for all techniques studied. However, for on-site TWA analysis of THMs in natural waters, the calibration standard(s ionic strength conditions, must be carefully matched to natural water conditions to properly quantitate THM concentrations. The data obtained from the TWA method may better reflect actual natural water conditions.

  2. A novel power spectrum calculation method using phase-compensation and weighted averaging for the estimation of ultrasound attenuation.

    Science.gov (United States)

    Heo, Seo Weon; Kim, Hyungsuk

    2010-05-01

    An estimation of ultrasound attenuation in soft tissues is critical in the quantitative ultrasound analysis since it is not only related to the estimations of other ultrasound parameters, such as speed of sound, integrated scatterers, or scatterer size, but also provides pathological information of the scanned tissue. However, estimation performances of ultrasound attenuation are intimately tied to the accurate extraction of spectral information from the backscattered radiofrequency (RF) signals. In this paper, we propose two novel techniques for calculating a block power spectrum from the backscattered ultrasound signals. These are based on the phase-compensation of each RF segment using the normalized cross-correlation to minimize estimation errors due to phase variations, and the weighted averaging technique to maximize the signal-to-noise ratio (SNR). The simulation results with uniform numerical phantoms demonstrate that the proposed method estimates local attenuation coefficients within 1.57% of the actual values while the conventional methods estimate those within 2.96%. The proposed method is especially effective when we deal with the signal reflected from the deeper depth where the SNR level is lower or when the gated window contains a small number of signal samples. Experimental results, performed at 5MHz, were obtained with a one-dimensional 128 elements array, using the tissue-mimicking phantoms also show that the proposed method provides better estimation results (within 3.04% of the actual value) with smaller estimation variances compared to the conventional methods (within 5.93%) for all cases considered. Copyright 2009 Elsevier B.V. All rights reserved.

  3. Self-weight effect in the measurement of the volume of silicon spheres

    Science.gov (United States)

    Mari, D.; Massa, E.; Kuramoto, N.; Mana, G.

    2018-04-01

    The volume of 28Si spheres about 94 mm in diameter is an input datum for the determination of the Avogadro constant. We report a finite element analysis of the self-weight effect on the volume determination via optical interferometric measurements of the sphere diameters. The self-weight expansion or shrinkage of the equatorial diameters, which ranges from  -31 pm to  +180 pm, depends on the southern latitude of the supports.

  4. Low Goiter Rate Associated with Small Average Thyroid Volume in Schoolchildren after the Elimination of Iodine Deficiency Disorders.

    Directory of Open Access Journals (Sweden)

    Peihua Wang

    Full Text Available After the implementation of the universal salt iodization (USI program in 1996, seven cross-sectional school-based surveys have been conducted to monitor iodine deficiency disorders (IDD among children in eastern China.This study aimed to examine the correlation of total goiter rate (TGR with average thyroid volume (Tvol and urinary iodine concentration (UIC in Jiangsu province after IDD elimination.Probability-proportional-to-size sampling was applied to select 1,200 children aged 8-10 years old in 30 clusters for each survey in 1995, 1997, 1999, 2001, 2002, 2005, 2009 and 2011. We measured Tvol using ultrasonography in 8,314 children and measured UIC (4,767 subjects and salt iodine (10,184 samples using methods recommended by the World Health Organization. Tvol was used to calculate TGR based on the reference criteria specified for sex and body surface area (BSA.TGR decreased from 55.2% in 1997 to 1.0% in 2009, and geometric means of Tvol decreased from 3.63 mL to 1.33 mL, along with the UIC increasing from 83 μg/L in 1995 to 407 μg/L in 1999, then decreasing to 243 μg/L in 2005, and then increasing to 345 μg/L in 2011. In the low goiter population (TGR 300 μg/L was associated with a smaller average Tvol in children.After IDD elimination in Jiangsu province in 2001, lower TGR was associated with smaller average Tvol. Average Tvol was more sensitive than TGR in detecting the fluctuation of UIC. A UIC of 300 μg/L may be defined as a critical value for population level iodine status monitoring.

  5. Effect of the averaging volume and algorithm on the in situ electric field for uniform electric- and magnetic-field exposures

    International Nuclear Information System (INIS)

    Hirata, Akimasa; Takano, Yukinori; Fujiwara, Osamu; Kamimura, Yoshitsugu

    2010-01-01

    The present study quantified the volume-averaged in situ electric field in nerve tissues of anatomically based numeric Japanese male and female models for exposure to extremely low-frequency electric and magnetic fields. A quasi-static finite-difference time-domain method was applied to analyze this problem. The motivation of our investigation is that the dependence of the electric field induced in nerve tissue on the averaging volume/distance is not clear, while a cubical volume of 5 x 5 x 5 mm 3 or a straight-line segment of 5 mm is suggested in some documents. The influence of non-nerve tissue surrounding nerve tissue is also discussed by considering three algorithms for calculating the averaged in situ electric field in nerve tissue. The computational results obtained herein reveal that the volume-averaged electric field in the nerve tissue decreases with the averaging volume. In addition, the 99th percentile value of the volume-averaged in situ electric field in nerve tissue is more stable than that of the maximal value for different averaging volume. When including non-nerve tissue surrounding nerve tissue in the averaging volume, the resultant in situ electric fields were not so dependent on the averaging volume as compared to the case excluding non-nerve tissue. In situ electric fields averaged over a distance of 5 mm were comparable or larger than that for a 5 x 5 x 5 mm 3 cube depending on the algorithm, nerve tissue considered and exposure scenarios. (note)

  6. Legacy tree data: A national database of detailed tree measurements for volume, weight, and physical properties

    Science.gov (United States)

    P.J. Radtke; D.M. Walker; A.R. Weiskittel; J. Frank; J.W. Coulston; J.A. Westfall

    2015-01-01

    Forest mensurationists in the United States have expended considerable effort over the past century making detailed observations of trees’ dimensions. In recent decades efforts have focused increasingly on weights and physical properties. Work is underway to compile original measurements from past volume, taper, and weight or biomass studies for North American tree...

  7. Liver volume in thalassaemia major: relationship with body weight, serum ferritin, and liver function

    Energy Technology Data Exchange (ETDEWEB)

    Chan Yuleung; Law Manyee; Howard, Robert [Chinese University of Hong Kong, Department of Diagnostic Radiology and Organ Imaging, Prince of Wales Hospital, Hong Kong (China); Li Chikong; Chik Kiwai [Chinese University of Hong Kong, Department of Paediatrics, Prince of Wales Hospital, Hong Kong (China)

    2005-02-01

    It is not known whether body weight alone can adjust for the volume of liver in the calculation of the chelating dose in {beta}-thalassaemia major patients, who frequently have iron overload and hepatitis. The hypothesis is that liver volume in children and adolescents suffering from {beta}-thalassaemia major is affected by ferritin level and liver function. Thirty-five {beta}-thalassaemia major patients aged 7-18 years and 35 age- and sex-matched controls had liver volume measured by MRI. Serum alanine aminotransferase (ALT) and ferritin levels were obtained in the thalassaemia major patients. Body weight explained 65 and 86% of the change in liver volume in {beta}-thalassaemia major patients and age-matched control subjects, respectively. Liver volume/kilogram body weight was significantly higher (P<0.001) in thalassaemia major patients than in control subjects. There was a significant correlation between ALT level and liver volume/kilogram body weight (r=0.55, P=0.001). Patients with elevated ALT had significantly higher liver volume/kilogram body weight (mean 42.9{+-}12 cm{sup 3}/kg) than control subjects (mean 23.4{+-}3.6 cm{sup 3}/kg) and patients with normal ALT levels (mean 27.4{+-}3.6 cm{sup 3}/kg). Body weight is the most important single factor for liver-volume changes in thalassaemia major patients, but elevated ALT also has a significant role. Direct liver volume measurement for chelation dose adjustment may be advantageous in patients with elevated ALT. (orig.)

  8. Area- and depth- weighted averages of selected SSURGO variables for the conterminous United States and District of Columbia

    Science.gov (United States)

    Wieczorek, Michael

    2014-01-01

    This digital data release consists of seven data files of soil attributes for the United States and the District of Columbia. The files are derived from National Resources Conservations Service’s (NRCS) Soil Survey Geographic database (SSURGO). The data files can be linked to the raster datasets of soil mapping unit identifiers (MUKEY) available through the NRCS’s Gridded Soil Survey Geographic (gSSURGO) database (http://www.nrcs.usda.gov/wps/portal/nrcs/detail/soils/survey/geo/?cid=nrcs142p2_053628). The associated files, named DRAINAGECLASS, HYDRATING, HYDGRP, HYDRICCONDITION, LAYER, TEXT, and WTDEP are area- and depth-weighted average values for selected soil characteristics from the SSURGO database for the conterminous United States and the District of Columbia. The SSURGO tables were acquired from the NRCS on March 5, 2014. The soil characteristics in the DRAINAGE table are drainage class (DRNCLASS), which identifies the natural drainage conditions of the soil and refers to the frequency and duration of wet periods. The soil characteristics in the HYDRATING table are hydric rating (HYDRATE), a yes/no field that indicates whether or not a map unit component is classified as a "hydric soil". The soil characteristics in the HYDGRP table are the percentages for each hydrologic group per MUKEY. The soil characteristics in the HYDRICCONDITION table are hydric condition (HYDCON), which describes the natural condition of the soil component. The soil characteristics in the LAYER table are available water capacity (AVG_AWC), bulk density (AVG_BD), saturated hydraulic conductivity (AVG_KSAT), vertical saturated hydraulic conductivity (AVG_KV), soil erodibility factor (AVG_KFACT), porosity (AVG_POR), field capacity (AVG_FC), the soil fraction passing a number 4 sieve (AVG_NO4), the soil fraction passing a number 10 sieve (AVG_NO10), the soil fraction passing a number 200 sieve (AVG_NO200), and organic matter (AVG_OM). The soil characteristics in the TEXT table are

  9. An upscaled two-equation model of transport in porous media through unsteady-state closure of volume averaged formulations

    Science.gov (United States)

    Chaynikov, S.; Porta, G.; Riva, M.; Guadagnini, A.

    2012-04-01

    We focus on a theoretical analysis of nonreactive solute transport in porous media through the volume averaging technique. Darcy-scale transport models based on continuum formulations typically include large scale dispersive processes which are embedded in a pore-scale advection diffusion equation through a Fickian analogy. This formulation has been extensively questioned in the literature due to its inability to depict observed solute breakthrough curves in diverse settings, ranging from the laboratory to the field scales. The heterogeneity of the pore-scale velocity field is one of the key sources of uncertainties giving rise to anomalous (non-Fickian) dispersion in macro-scale porous systems. Some of the models which are employed to interpret observed non-Fickian solute behavior make use of a continuum formulation of the porous system which assumes a two-region description and includes a bimodal velocity distribution. A first class of these models comprises the so-called ''mobile-immobile'' conceptualization, where convective and dispersive transport mechanisms are considered to dominate within a high velocity region (mobile zone), while convective effects are neglected in a low velocity region (immobile zone). The mass exchange between these two regions is assumed to be controlled by a diffusive process and is macroscopically described by a first-order kinetic. An extension of these ideas is the two equation ''mobile-mobile'' model, where both transport mechanisms are taken into account in each region and a first-order mass exchange between regions is employed. Here, we provide an analytical derivation of two region "mobile-mobile" meso-scale models through a rigorous upscaling of the pore-scale advection diffusion equation. Among the available upscaling methodologies, we employ the Volume Averaging technique. In this approach, the heterogeneous porous medium is supposed to be pseudo-periodic, and can be represented through a (spatially) periodic unit cell

  10. Normal gray and white matter volume after weight restoration in adolescents with anorexia nervosa.

    Science.gov (United States)

    Lázaro, Luisa; Andrés, Susana; Calvo, Anna; Cullell, Clàudia; Moreno, Elena; Plana, M Teresa; Falcón, Carles; Bargalló, Núria; Castro-Fornieles, Josefina

    2013-12-01

    The aim of this study was to determine whether treated, weight-stabilized adolescents with anorexia nervosa (AN) present brain volume differences in comparison with healthy controls. Thirty-five adolescents with weight-recovered AN and 17 healthy controls were assessed by means of psychopathology scales and magnetic resonance imaging. Axial three-dimensional T1-weighted images were obtained in a 1.5 Tesla scanner and analyzed using optimized voxel-based morphometry (VBM). There were no significant differences between controls and weight-stabilized AN patients with regard to global volumes of either gray or white brain matter, or in the regional VBM study. Differences were not significant between patients with psychopharmacological treatment and without, between those with amenorrhea and without, as well as between patients with restrictive versus purgative AN. The present findings reveal no global or regional gray or white matter abnormalities in this sample of adolescents following weight restoration. Copyright © 2013 Wiley Periodicals, Inc.

  11. VOLUME ESTIMATION, DRY WEIGHT, OIL CONTENT AND QUANTITY OF FENCEPOSTS OF CANDEIA (Eremanthus erythropappus (DC MacLeish

    Directory of Open Access Journals (Sweden)

    José Roberto Soares Scolforo

    2004-06-01

    Full Text Available This research aimed at studying the behavior of volume, dry weight, oil content and fence post quantity per diametric class of candeia; to define its stack factor, with and without diametric class control; and to determine equations for estimating the main stem and branches volume, dry weight and oil content of the hole tree, trunk, branches and leaves and fencepost quantity. Data were obtained from a forest inventory carried out in a native candeia forest located in Aiuruoca county, Minas Gerais state - Brazil. Tree volume was calculated through the Huber formula and oil extraction methods employed were “the solvent method” and “vapor hauling method”. For estimation volume, dry weight, oil content and fencepost number the traditional double entry models were used. The oil weight in 1 cubic meter of wood of small dimensions, trees between 5 and 10cm, is around 6 kilos, while the oil content of the largest trees, between 40 and 45cm, is around 11 kilos. The same tendency is observed for the wood volume, without bark, and in the volume of piled up wood, although in these last situations the magnitude of quantities are different. The oil content of candeia trees present the following behavior: in the stem and branches up to 3cm of diameter with bark, it varies from 1,02% to 1,37%, respectively to plants with diameter between 5 and 10cm and between 40 and 45cm; in the branches with less than 3cm of diameter with bark, it varies from 0,33% to 0,65%,respectively, to plants between 5 and 10cm and between 40 and 45cm of diameter; in the leaves it varies from 0,28% to 0,77%, respectively, for plants between 5-10cm and between 40-45cm of diameter. The average stack factor is 1.9087 and diminishes as diameter classes increases. The best model for estimating oil content, dry weight, fence post quantity and volume is the logarithmic form of Schumacher-Hall model.

  12. Birth weight and neonatal adiposity prediction using fractional limb volume obtained with 3D ultrasound.

    Science.gov (United States)

    O'Connor, Clare; O'Higgins, Amy; Doolan, Anne; Segurado, Ricardo; Stuart, Bernard; Turner, Michael J; Kennelly, Máireád M

    2014-01-01

    The objective of this investigation was to study fetal thigh volume throughout gestation and explore its correlation with birth weight and neonatal body composition. This novel technique may improve birth weight prediction and lead to improved detection rates for fetal growth restriction. Fractional thigh volume (TVol) using 3D ultrasound, fetal biometry and soft tissue thickness were studied longitudinally in 42 mother-infant pairs. The percentages of neonatal body fat, fat mass and fat-free mass were determined using air displacement plethysmography. Correlation and linear regression analyses were performed. Linear regression analysis showed an association between TVol and birth weight. TVol at 33 weeks was also associated with neonatal fat-free mass. There was no correlation between TVol and neonatal fat mass. Abdominal circumference, estimated fetal weight (EFW) and EFW centile showed consistent correlations with birth weight. Thigh volume demonstrated an additional independent contribution to birth weight prediction when added to the EFW centile from the 38-week scan (p = 0.03). Fractional TVol performed at 33 weeks gestation is correlated with birth weight and neonatal lean body mass. This screening test may highlight those at risk of fetal growth restriction or macrosomia.

  13. Comparing Weighted and Unweighted Grade Point Averages in Predicting College Success of Diverse and Low-Income College Students

    Science.gov (United States)

    Warne, Russell T.; Nagaishi, Chanel; Slade, Michael K.; Hermesmeyer, Paul; Peck, Elizabeth Kimberli

    2014-01-01

    While research has shown the statistical significance of high school grade point averages (HSGPAs) in predicting future academic outcomes, the systems with which HSGPAs are calculated vary drastically across schools. Some schools employ unweighted grades that carry the same point value regardless of the course in which they are earned; other…

  14. Greater-than-Class C low-level waste characterization. Appendix I: Impact of concentration averaging low-level radioactive waste volume projections

    International Nuclear Information System (INIS)

    Tuite, P.; Tuite, K.; O'Kelley, M.; Ely, P.

    1991-08-01

    This study provides a quantitative framework for bounding unpackaged greater-than-Class C low-level radioactive waste types as a function of concentration averaging. The study defines the three concentration averaging scenarios that lead to base, high, and low volumetric projections; identifies those waste types that could be greater-than-Class C under the high volume, or worst case, concentration averaging scenario; and quantifies the impact of these scenarios on identified waste types relative to the base case scenario. The base volume scenario was assumed to reflect current requirements at the disposal sites as well as the regulatory views. The high volume scenario was assumed to reflect the most conservative criteria as incorporated in some compact host state requirements. The low volume scenario was assumed to reflect the 10 CFR Part 61 criteria as applicable to both shallow land burial facilities and to practices that could be employed to reduce the generation of Class C waste types

  15. VOLUME ESTIMATIONS FOR COMBINED FREE-WEIGHT AND RUBBER-BAND RESISTANCE EXERCISE

    OpenAIRE

    C. Shoepe, Todd; Vejarano, Gustavo; P. Reyes, Nathan; M. Gobreial, Nicole; M. Ricci, Jeanette

    2017-01-01

    Volume, or the total work performed during resistance training is one of the vital variables of resistance exercise programming. The most common definition in use by practitioners is sets x reps x external weight. While appropriate for linear loading incurred through free-weight resistance exercise, this inadequately addresses the nonlinear loading incurred with rubber resistance, a relatively new loading technique. The purpose of this investigation was to derive a theoretical model to descri...

  16. Path integral for stochastic inflation: Nonperturbative volume weighting, complex histories, initial conditions, and the end of inflation

    Science.gov (United States)

    Gratton, Steven

    2011-09-01

    In this paper we present a path integral formulation of stochastic inflation. Volume weighting can be naturally implemented from this new perspective in a very straightforward way when compared to conventional Langevin approaches. With an in-depth study of inflation in a quartic potential, we investigate how the inflaton evolves and how inflation typically ends both with and without volume weighting. The calculation can be carried to times beyond those accessible to conventional Fokker-Planck approaches. Perhaps unexpectedly, complex histories sometimes emerge with volume weighting. The reward for this excursion into the complex plane is an insight into how volume-weighted inflation both loses memory of initial conditions and ends via slow roll. The slow-roll end of inflation mitigates certain “Youngness Paradox”-type criticisms of the volume-weighted paradigm. Thus it is perhaps time to rehabilitate proper-time volume weighting as a viable measure for answering at least some interesting cosmological questions.

  17. Path integral for stochastic inflation: Nonperturbative volume weighting, complex histories, initial conditions, and the end of inflation

    International Nuclear Information System (INIS)

    Gratton, Steven

    2011-01-01

    In this paper we present a path integral formulation of stochastic inflation. Volume weighting can be naturally implemented from this new perspective in a very straightforward way when compared to conventional Langevin approaches. With an in-depth study of inflation in a quartic potential, we investigate how the inflaton evolves and how inflation typically ends both with and without volume weighting. The calculation can be carried to times beyond those accessible to conventional Fokker-Planck approaches. Perhaps unexpectedly, complex histories sometimes emerge with volume weighting. The reward for this excursion into the complex plane is an insight into how volume-weighted inflation both loses memory of initial conditions and ends via slow roll. The slow-roll end of inflation mitigates certain ''Youngness Paradox''-type criticisms of the volume-weighted paradigm. Thus it is perhaps time to rehabilitate proper-time volume weighting as a viable measure for answering at least some interesting cosmological questions.

  18. Determination of average molecular weights on organic reactor coolants. I.- Freezing-point depression method for benzene solutions

    International Nuclear Information System (INIS)

    Carreira, M.

    1965-01-01

    As a working method for determination of changes in molecular mass that may occur by irradiation (pyrolytic-radiolytic decomposition) of polyphenyl reactor coolants, a cryoscopic technique has been developed which associated the basic simplicity of Beckman's method with some experimental refinements taken out of the equilibrium methods. A total of 18 runs were made on samples of napthalene, biphenyl, and the commercial mixtures OM-2 (Progil) and Santowax-R (Monsanto), with an average deviation from the theoretical molecular mass of 0.6%. (Author) 7 refs

  19. Weight, Volume, and Physical Properties of Major Hardwood Species in the Upland-South

    Science.gov (United States)

    Alexander Clark; Douglas R. Phillips; Douglas J. Frederick

    1986-01-01

    The weight, volume, and physical properties oftrees1 to 20 inchesd.b.h.were determined for sweetgum, yellow-poplar, hickory, post oak, scarlet oak, southern red oak, and white oakin northern Alabama and Mississippi, eastern Arkansas, southern Kentucky and Tennessee. Hard hardwoods, soft hardwoods, and individual species equations are presented for predicting green and...

  20. Weight, Volume, and Physical Properties of Major Hardwood Species in the Piedmont

    Science.gov (United States)

    Alexander Clark; Douglas R. Phillips; Douglas J. Frederick

    1986-01-01

    Weight, volume, and physical properties of trees 1 to 20 inches d.b.h.were determined for red maple, sweetgum, sycamore, yellow-poplar, elm, hickory, chestnut oak, scarlet oak, southern red oak, and white oak in the Piedmont of the Southeastern United States. A total of 772 trees were destructively sampled at 16 locations from Viryinia to Alabama. Hard hardwoods, soft...

  1. The role of haptic versus visual volume cues in the size-weight illusion.

    Science.gov (United States)

    Ellis, R R; Lederman, S J

    1993-03-01

    Three experiments establish the size-weight illusion as a primarily haptic phenomenon, despite its having been more traditionally considered an example of vision influencing haptic processing. Experiment 1 documents, across a broad range of stimulus weights and volumes, the existence of a purely haptic size-weight illusion, equal in strength to the traditional illusion. Experiment 2 demonstrates that haptic volume cues are both sufficient and necessary for a full-strength illusion. In contrast, visual volume cues are merely sufficient, and produce a relatively weaker effect. Experiment 3 establishes that congenitally blind subjects experience an effect as powerful as that of blindfolded sighted observers, thus demonstrating that visual imagery is also unnecessary for a robust size-weight illusion. The results are discussed in terms of their implications for both sensory and cognitive theories of the size-weight illusion. Applications of this work to a human factors design and to sensor-based systems for robotic manipulation are also briefly considered.

  2. Liver volume, intrahepatic fat and body weight in the course of a lifestyle interventional study. Analysis with quantitative MR-based methods

    International Nuclear Information System (INIS)

    Bongers, M.N.; Stefan, N.; Fritsche, A.; Haering, H.U.; Nikolaou, K.; Schick, F.; Machann, J.

    2015-01-01

    The aim of this study was to investigate potential associations between changes in liver volume, the amount of intrahepatic lipids (IHL) and body weight during lifestyle interventions. In a prospective study 150 patients with an increased risk for developing type 2 diabetes mellitus were included who followed a caloric restriction diet for 6 months. In the retrospective analysis 18 women and 9 men (age range 22-71 years) with an average body mass index (BMI) of 32 kg/m 2 were enrolled. The liver volume was determined at the beginning and after 6 months by three-dimensional magnetic resonance imaging (3D-MRI, echo gradient, opposed-phase) and IHLs were quantified by volume-selective MR spectroscopy in single voxel stimulated echo acquisition mode (STEAM). Univariable and multivariable correlation analyses between changes of liver volume (Δliver volume), intrahepatic lipids (ΔIHL) and body weight (ΔBW) were performed. Univariable correlation analysis in the whole study cohort showed associations between ΔIHL and ΔBW (r = 0.69; p < 0.0001), ΔIHL and Δliver volume (r = 0.66; p = 0.0002) as well as ΔBW and Δliver volume (r = 0.5; p = 0.0073). Multivariable correlation analysis revealed that changes of liver volume are primarily determined by changes in IHL independent of changes in body weight (β = 0.0272; 95 % CI: 0.0155-0.034; p < 0.0001). Changes of liver volume during lifestyle interventions are independent of changes of body weight primarily determined by changes of IHL. These results show the reversibility of augmented liver volume in steatosis if it is possible to reduce IHLs during lifestyle interventions. (orig.) [de

  3. The effect of wind shielding and pen position on the average daily weight gain and feed conversion rate of grower/finisher pigs

    DEFF Research Database (Denmark)

    Jensen, Dan B.; Toft, Nils; Cornou, Cécile

    2014-01-01

    of the effects of wind shielding, linear mixed models were fitted to describe the average daily weight gain and feed conversion rate of 1271 groups (14 individuals per group) of purebred Duroc, Yorkshire and Danish Landrace boars, as a function of shielding (yes/no), insert season (winter, spring, summer, autumn...... groups placed in the 1st and 4th pen (p=0.0001). A similar effect was not seen on smaller pigs. Pen placement appears to have no effect on feed conversion rate.No interaction effects between shielding and distance to the corridor could be demonstrated. Furthermore, in models including both factors......). The effect could not be tested for Yorkshire and Danish Landrace due to lack of data on these breeds. For groups of pigs above the average start weight, a clear tendency of higher growth rates at greater distances from the central corridor was observed, with the most significant differences being between...

  4. Generation of the covariance matrix for a set of nuclear data produced by collapsing a larger parent set through the weighted averaging of equivalent data points

    International Nuclear Information System (INIS)

    Smith, D.L.

    1987-01-01

    A method is described for generating the covariance matrix of a set of experimental nuclear data which has been collapsed in size by the averaging of equivalent data points belonging to a larger parent data set. It is assumed that the data values and covariance matrix for the parent set are provided. The collapsed set is obtained by a proper weighted-averaging procedure based on the method of least squares. It is then shown by means of the law of error propagation that the elements of the covariance matrix for the collapsed set are linear combinations of elements from the parent set covariance matrix. The coefficients appearing in these combinations are binary products of the same coefficients which appear as weighting factors in the data collapsing procedure. As an example, the procedure is applied to a collection of recently-measured integral neutron-fission cross-section ratios. (orig.)

  5. Ischemic lesion volume determination on diffusion weighted images vs. apparent diffusion coefficient maps.

    Science.gov (United States)

    Bråtane, Bernt Tore; Bastan, Birgul; Fisher, Marc; Bouley, James; Henninger, Nils

    2009-07-07

    Though diffusion weighted imaging (DWI) is frequently used for identifying the ischemic lesion in focal cerebral ischemia, the understanding of spatiotemporal evolution patterns observed with different analysis methods remains imprecise. DWI and calculated apparent diffusion coefficient (ADC) maps were serially obtained in rat stroke models (MCAO): permanent, 90 min, and 180 min temporary MCAO. Lesion volumes were analyzed in a blinded and randomized manner by 2 investigators using (i) a previously validated ADC threshold, (ii) visual determination of hypointense regions on ADC maps, and (iii) visual determination of hyperintense regions on DWI. Lesion volumes were correlated with 24 hour 2,3,5-triphenyltetrazoliumchloride (TTC)-derived infarct volumes. TTC-derived infarct volumes were not significantly different from the ADC and DWI-derived lesion volumes at the last imaging time points except for significantly smaller DWI lesions in the pMCAO model (p=0.02). Volumetric calculation based on TTC-derived infarct also correlated significantly stronger to volumetric calculation based on last imaging time point derived lesions on ADC maps than DWI (pdetermined lesion volumes on ADC maps and DWI by both investigators correlated significantly with threshold-derived lesion volumes on ADC maps with the former method demonstrating a stronger correlation. There was also a better interrater agreement for ADC map analysis than for DWI analysis. Ischemic lesion determination by ADC was more accurate in final infarct prediction, rater independent, and provided exclusive information on ischemic lesion reversibility.

  6. Global (volume-averaged) model of inductively coupled chlorine plasma : influence of Cl wall recombination and external heating on continuous and pulse-modulated plasmas

    NARCIS (Netherlands)

    Kemaneci, E.H.; Carbone, E.A.D.; Booth, J.P.; Graef, W.A.A.D.; Dijk, van J.; Kroesen, G.M.W.

    An inductively coupled radio-frequency plasma in chlorine is investigated via a global (volume-averaged) model, both in continuous and square wave modulated power input modes. After the power is switched off (in a pulsed mode) an ion–ion plasma appears. In order to model this phenomenon, a novel

  7. Quantity Distortion Effect in Consumers' Perception of Different Volumes and Weights of Money: A Pilot Study.

    Science.gov (United States)

    Guido, Gianluigi; Piper, Luigi; Prete, M Irene; Mileti, Antonio; Fonda, Marco

    2016-08-01

    Consumers tend to misunderstand the physical value of cash money by adopting improper anchors for their judgments (e.g., banknote size and shape, currency denominations, etc.). In a pilot study carried out on a sample of 242 participants (n = 116 men; M age = 29.6 year, SD = 10.8), a quantity distortion effect was demonstrated by evaluating consumers' misperceptions of different monetary quantities, either in terms of volume or weight, using banknotes of the same denomination (€50). A threshold value was found, for both volume (€876,324) and weight (€371,779), above (below) which consumers tend to overrate (underrate) monetary amounts. The theoretical and operative implications are discussed. © The Author(s) 2016.

  8. Effect of Pb-acetate on Testicle Weight and Volume of Mice

    Directory of Open Access Journals (Sweden)

    Israhnanto Isradji

    2011-12-01

    Design and Method: Eighty male mice placed in individual cages according to the group. Food and drink provided ad libitum. The treatment of male mice given for 6 weeks. Treatment with 0.2 ml distilled water to PI, P II were given a solution of 400 ppm Pb acetate total of 0.2 ml, P III was given a solution of 1000 ppm Pb acetate as many as 0.2 ml, and P IV were given a solution of 2000 ppm Pb acetate total of 0,2 ml by using a gastric sonde, every morning once a day for 42 days. At week 7, mice were surgery to take the testis. Testicular volume was measured and weighed. Data were analyzed by ANOVA, hypothesis is accepted when p 0.05, testis weight obtained by ANOVA test probability of 0.216 (> 0.05, mean Pb -acetate had no effect on testis weight and volume. Conclusion: Pb-acetate had no effect on testis weight and volume (Sains Medika, 3(2:150-156.

  9. No overall relationship between average daily weight gain and the serological response to Mycoplasma hyopneumoniae and Actinobacillus pleuropneumoniae in eight chronically infected Danish swine herds

    DEFF Research Database (Denmark)

    Andreasen, Margit; Mousing, Jan; Thomsen, Lars Krogsgård

    2001-01-01

    approximately 4 weeks of age), and sera were analyzed for antibodies to Mycoplasma hyopneumoniae and Actinobacillus pleuropneumoniae serotypes 2, 5-7 and 12. Mixed analysis of covariance analyzed the relationship between the average daily weight gain and a categorical variable defining seroconversion as none...... most pigs included in the study were subclinically infected, or because a temporary negative influence of the infections is hidden due to an increased growth in the period following infection. In conclusion. at least in these eight herds, seroresponses to M. hyopneumoniae and A. pleuropneumoniae could...

  10. Memory function and hippocampal volumes in preterm born very-low-birth-weight (VLBW) young adults.

    Science.gov (United States)

    Aanes, Synne; Bjuland, Knut Jørgen; Skranes, Jon; Løhaugen, Gro C C

    2015-01-15

    The hippocampi are regarded as core structures for learning and memory functions, which is important for daily functioning and educational achievements. Previous studies have linked reduction in hippocampal volume to working memory problems in very low birth weight (VLBW; ≤ 1500 g) children and reduced general cognitive ability in VLBW adolescents. However, the relationship between memory function and hippocampal volume has not been described in VLBW subjects reaching adulthood. The aim of the study was to investigate memory function and hippocampal volume in VLBW young adults, both in relation to perinatal risk factors and compared to term born controls, and to look for structure-function relationships. Using Wechsler Memory Scale-III and MRI, we included 42 non-disabled VLBW and 61 control individuals at age 19-20 years, and related our findings to perinatal risk factors in the VLBW-group. The VLBW young adults achieved lower scores on several subtests of the Wechsler Memory Scale-III, resulting in lower results in the immediate memory indices (visual and auditory), the working memory index, and in the visual delayed and general memory delayed indices, but not in the auditory delayed and auditory recognition delayed indices. The VLBW group had smaller absolute and relative hippocampal volumes than the controls. In the VLBW group inferior memory function, especially for the working memory index, was related to smaller hippocampal volume, and both correlated with lower birth weight and more days in the neonatal intensive care unit (NICU). Our results may indicate a structural-functional relationship in the VLBW group due to aberrant hippocampal development and functioning after preterm birth. Copyright © 2014 Elsevier Inc. All rights reserved.

  11. A randomised clinical trial on the efficacy of oxytetracycline dose through water medication of nursery pigs on diarrhoea, faecal shedding of Lawsonia intracellularis and average daily weight gain.

    Science.gov (United States)

    Larsen, Inge; Hjulsager, Charlotte Kristiane; Holm, Anders; Olsen, John Elmerdahl; Nielsen, Søren Saxmose; Nielsen, Jens Peter

    2016-01-01

    Oral treatment with antimicrobials is widely used in pig production for the control of gastrointestinal infections. Lawsonia intracellularis (LI) causes enteritis in pigs older than six weeks of age and is commonly treated with antimicrobials. The objective of this study was to evaluate the efficacy of three oral dosage regimens (5, 10 and 20mg/kg body weight) of oxytetracycline (OTC) in drinking water over a five-day period on diarrhoea, faecal shedding of LI and average daily weight gain (ADG). A randomised clinical trial was carried out in four Danish pig herds. In total, 539 animals from 37 batches of nursery pigs were included in the study. The dosage regimens were randomly allocated to each batch and initiated at presence of assumed LI-related diarrhoea. In general, all OTC doses used for the treatment of LI infection resulted in reduced diarrhoea and LI shedding after treatment. Treatment with a low dose of 5mg/kg OTC per kg body weight, however, tended to cause more watery faeces and resulted in higher odds of pigs shedding LI above detection level when compared to medium and high doses (with odds ratios of 5.5 and 8.4, respectively). No association was found between the dose of OTC and the ADG. In conclusion, a dose of 5mg OTC per kg body weight was adequate for reducing the high-level LI shedding associated with enteropathy, but a dose of 10mg OTC per kg body weight was necessary to obtain a maximum reduction in LI shedding. Copyright © 2015 Elsevier B.V. All rights reserved.

  12. The impact of hospital market structure on patient volume, average length of stay, and the cost of care.

    Science.gov (United States)

    Robinson, J C; Luft, H S

    1985-12-01

    A variety of recent proposals rely heavily on market forces as a means of controlling hospital cost inflation. Sceptics argue, however, that increased competition might lead to cost-increasing acquisitions of specialized clinical services and other forms of non-price competition as means of attracting physicians and patients. Using data from hospitals in 1972 we analyzed the impact of market structure on average hospital costs, measured in terms of both cost per patient and cost per patient day. Under the retrospective reimbursement system in place at the time, hospitals in more competitive environments exhibited significantly higher costs of production than did those in less competitive environments.

  13. Application of method of volume averaging coupled with time resolved PIV to determine transport characteristics of turbulent flows in porous bed

    Science.gov (United States)

    Patil, Vishal; Liburdy, James

    2012-11-01

    Turbulent porous media flows are encountered in catalytic bed reactors and heat exchangers. Dispersion and mixing properties of these flows play an essential role in efficiency and performance. In an effort to understand these flows, pore scale time resolved PIV measurements in a refractive index matched porous bed were made. Pore Reynolds numbers, based on hydraulic diameter and pore average velocity, were varied from 400-4000. Jet-like flows and recirculation regions associated with large scale structures were found to exist. Coherent vortical structures which convect at approximately 0.8 times the pore average velocity were identified. These different flow regions exhibited different turbulent characteristics and hence contributed unequally to global transport properties of the bed. The heterogeneity present within a pore and also from pore to pore can be accounted for in estimating transport properties using the method of volume averaging. Eddy viscosity maps and mean velocity field maps, both obtained from PIV measurements, along with the method of volume averaging were used to predict the dispersion tensor versus Reynolds number. Asymptotic values of dispersion compare well to existing correlations. The role of molecular diffusion was explored by varying the Schmidt number and molecular diffusion was found to play an important role in tracer transport, especially in recirculation regions. Funding by NSF grant 0933857, Particulate and Multiphase Processing.

  14. Positive outcome of average volume-assured pressure support mode of a Respironics V60 Ventilator in acute exacerbation of chronic obstructive pulmonary disease: a case report

    Directory of Open Access Journals (Sweden)

    Okuda Miyuki

    2012-09-01

    Full Text Available Abstract Introduction We were able to treat a patient with acute exacerbation of chronic obstructive pulmonary disease who also suffered from sleep-disordered breathing by using the average volume-assured pressure support mode of a Respironics V60 Ventilator (Philips Respironics: United States. This allows a target tidal volume to be set based on automatic changes in inspiratory positive airway pressure. This removed the need to change the noninvasive positive pressure ventilation settings during the day and during sleep. The Respironics V60 Ventilator, in the average volume-assured pressure support mode, was attached to our patient and improved and stabilized his sleep-related hypoventilation by automatically adjusting force to within an acceptable range. Case presentation Our patient was a 74-year-old Japanese man who was hospitalized for treatment due to worsening of dyspnea and hypoxemia. He was diagnosed with acute exacerbation of chronic obstructive pulmonary disease and full-time biphasic positive airway pressure support ventilation was initiated. Our patient was temporarily provided with portable noninvasive positive pressure ventilation at night-time following an improvement in his condition, but his chronic obstructive pulmonary disease again worsened due to the recurrence of a respiratory infection. During the initial exacerbation, his tidal volume was significantly lower during sleep (378.9 ± 72.9mL than while awake (446.5 ± 63.3mL. A ventilator that allows ventilation to be maintained by automatically adjusting the inspiratory force to within an acceptable range was attached in average volume-assured pressure support mode, improving his sleep-related hypoventilation, which is often associated with the use of the Respironics V60 Ventilator. Polysomnography performed while our patient was on noninvasive positive pressure ventilation revealed obstructive sleep apnea syndrome (apnea-hypopnea index = 14, suggesting that his chronic

  15. Anthropometric parameters: weight height, body mass index and mammary volume in relationship with the mammographic pattern

    International Nuclear Information System (INIS)

    Perez-Candela, V.; Busto, C.; Avila, R.; Marrero, M. G.; Liminana, J. M.; Orengo, J. C.

    2001-01-01

    A prospective study to attempt to relate the anthropometric parameters of height, weight, body mass index as well as age with the mammographic patterns obtained for the patients and obtain an anthropometric profile was carried out. The study was performed in 1.000 women who underwent a mammography in cranial-caudal and medial lateral oblique projection of both breasts, independently of whether they were screened or diagnosed. Prior to the performance of the mammography, weight and height were obtained, and this was also performed by the same technicians, and the patient were asked their bra size to deduce breast volume. With the weight, the body mass index of Quetelet was calculated (weight [kg]/height''2 (ml). After reading the mammography, the patient was assigned to one of the four mammographic patterns considered in the BIRADS (Breast Imaging Reporting and Data System) established by the ACR (American College of Radiology): type I (fat). type II (disperse fibroglandular densities), type III (fibroglandular densities distributed heterogeneously), type 4 (dense). The results were introduced into a computer database and the SPSS 8.0 statistical program was applied, using the statistical model of multivariant logistic regression. In women under 40 years, with normal weight, the dense breast pattern accounted for 67.8% and as the body mass index (BMI) increased, this pattern decreased to 25.1%. The fat pattern is 20% and as the BMI increases, this increased to 80%. In 40-60 year old women with normal weight, the dense pattern accounts for 44% and decreases to 20.9% in the grades II, III and IV obese. The fat pattern is 11.1% and increases to 53.7% in the grade II, III and IV obese. In women over 60 with normal, the dense pattern accounts for 19.3% and and decreases to 13% in the grade III obese. The fat pattern is 5.3% and increases to 20.2% in the grade iii of obesity. As age increases, the probability of presenting a mammographic pattern with a fat image in the

  16. SU-D-213-04: Accounting for Volume Averaging and Material Composition Effects in An Ionization Chamber Array for Patient Specific QA

    International Nuclear Information System (INIS)

    Fugal, M; McDonald, D; Jacqmin, D; Koch, N; Ellis, A; Peng, J; Ashenafi, M; Vanek, K

    2015-01-01

    Purpose: This study explores novel methods to address two significant challenges affecting measurement of patient-specific quality assurance (QA) with IBA’s Matrixx Evolution™ ionization chamber array. First, dose calculation algorithms often struggle to accurately determine dose to the chamber array due to CT artifact and algorithm limitations. Second, finite chamber size and volume averaging effects cause additional deviation from the calculated dose. Methods: QA measurements were taken with the Matrixx positioned on the treatment table in a solid-water Multi-Cube™ phantom. To reduce the effect of CT artifact, the Matrixx CT image set was masked with appropriate materials and densities. Individual ionization chambers were masked as air, while the high-z electronic backplane and remaining solid-water material were masked as aluminum and water, respectively. Dose calculation was done using Varian’s Acuros XB™ (V11) algorithm, which is capable of predicting dose more accurately in non-biologic materials due to its consideration of each material’s atomic properties. Finally, the exported TPS dose was processed using an in-house algorithm (MATLAB) to assign the volume averaged TPS dose to each element of a corresponding 2-D matrix. This matrix was used for comparison with the measured dose. Square fields at regularly-spaced gantry angles, as well as selected patient plans were analyzed. Results: Analyzed plans showed improved agreement, with the average gamma passing rate increasing from 94 to 98%. Correction factors necessary for chamber angular dependence were reduced by 67% compared to factors measured previously, indicating that previously measured factors corrected for dose calculation errors in addition to true chamber angular dependence. Conclusion: By comparing volume averaged dose, calculated with a capable dose engine, on a phantom masked with correct materials and densities, QA results obtained with the Matrixx Evolution™ can be significantly

  17. The Effect of Ramadan Fasting and Weight-Lifting Training on Plasma Volume, Glucose and Lipids Profile of Male Weight-Lifters

    Directory of Open Access Journals (Sweden)

    Seyed Morteza Tayebi

    Full Text Available Objective(sThe purpose of the present study was to evaluate the effect of Ramadan fasting and weight-lifting training on plasma volume, glucose, and lipids profile of male weight-lifter.Materials and MethodsForty male weight-lifters were recruited and divided into 4 groups (n=10 each and as the following groups: control (C, fasting (F, training (T and fasting-training (F-T. The T and F-T groups performed weight-lifting technique trainings and hypertrophy body building (3 sessions/week, 90 min/session. All subjects were asked to complete a medical examination as well as a medical questionnaire to ensure that they were not taking any medication, were free of cardiac, respiratory, renal, and metabolic diseases, and were not using steroids. Blood samples were taken at 24 hr before and 24 hr after one month of fasting and weight-lifting exercise. The plasma volume, fasting blood sugar (FBS, lipid profiles, and lipoproteins were analyzed in blood samples. ResultsBody weight and plasma volume showed significant (P< 0.05 decrease and increase in the F group (P< 0.05 respectively. Also, a significant reduction was observed in F-T group body weight (P< 0.01. A significant increase was found in FBS level of F group (P< 0.05. The lipid profiles and lipoproteins didn’t change significantly in C, F, T and the F-T groups.ConclusionThe effect of Ramadan fasting on body weight and plasma volumes may be closely related to the nutritional diet or biochemical response to fasting.

  18. Characterization of Volume F Trash from Four Recent STS Missions: Weights, Categorization, Water Content

    Science.gov (United States)

    Strayer, Richard F.; Hummerick, Mary E.; Richards, Jeffrey T.; McCoy, LaShelle E.; Roberts, Michael S.; Wheeler, Raymond M.

    2011-01-01

    The fate of space-generated solid wastes, including trash, for future missions is under consideration by NASA. Several potential treatment options are under consideration and active technology development. Potential fates for space-generated solid wastes are: Storage without treatment; storage after treatment(s) including volume reduction, water recovery, sterilization, and recovery plus recycling of waste materials. Recycling might be important for partial or full closure scenarios because of the prohibitive costs associated with resupply of consumable materials. For this study, we determined the composition of trash returned from four recent STS missions. The trash material was 'Volume F' trash and other trash, in large zip-lock bags, that accompanied the Volume F trash. This is the first of two submitted papers on these wastes. This one will cover trash content, weight and water content. The other will report on the microbial Characterization of this trash. STS trash was usually made available within 2 days of landing at KSC. The Volume F bag was weighed, opened and the contents were catalogued and placed into one of the following categories: food waste (and containers), drink containers, personal hygiene items - including EVA maximum absorbent garments (MAGs)and Elbow packs (daily toilet wipes, etc), paper, and packaging materials - plastic firm and duct tape. Trash generation rates for the four STS missions: Total wet trash was 0.602 plus or minus 0.089 kg(sub wet) crew(sup -1) d(sup -1) containing about 25% water at 0.154 plus or minus 0.030 kg(sub water) crew(sup -1) d(sup -1) (avg plus or minus stdev). Cataloguing by category: personal hygiene wastes accounted for 50% of the total trash and 69% of the total water for the four missions; drink items were 16% of total weight and 16% water; food wastes were 22% of total weight and 15% of the water; office waste and plastic film were 2% and 11% of the total waste and did not contain any water. The results can be

  19. Effects of Gestational Age and Birth Weight on Brain Volumes in Healthy 9 Year-Old Children

    NARCIS (Netherlands)

    van Soelen, I.L.C.; Brouwer, R.M.; Peper, J.S.; van Beijsterveldt, C.E.M.; van Leeuwen, M.; de Vries, L.S.; Kahn, R.S.; Hulshoff Pol, H.E.; Boomsma, D.I.

    2010-01-01

    Objective: To assess the effects of gestational age and birth weight on brain volumes in a population-based sample of normal developing children at the age of 9 years. Study design: A total of 192 children from twin births were included in the analyses. Data on gestational age and birth weight were

  20. State Averages

    Data.gov (United States)

    U.S. Department of Health & Human Services — A list of a variety of averages for each state or territory as well as the national average, including each quality measure, staffing, fine amount and number of...

  1. A highly detailed FEM volume conductor model based on the ICBM152 average head template for EEG source imaging and TCS targeting.

    Science.gov (United States)

    Haufe, Stefan; Huang, Yu; Parra, Lucas C

    2015-08-01

    In electroencephalographic (EEG) source imaging as well as in transcranial current stimulation (TCS), it is common to model the head using either three-shell boundary element (BEM) or more accurate finite element (FEM) volume conductor models. Since building FEMs is computationally demanding and labor intensive, they are often extensively reused as templates even for subjects with mismatching anatomies. BEMs can in principle be used to efficiently build individual volume conductor models; however, the limiting factor for such individualization are the high acquisition costs of structural magnetic resonance images. Here, we build a highly detailed (0.5mm(3) resolution, 6 tissue type segmentation, 231 electrodes) FEM based on the ICBM152 template, a nonlinear average of 152 adult human heads, which we call ICBM-NY. We show that, through more realistic electrical modeling, our model is similarly accurate as individual BEMs. Moreover, through using an unbiased population average, our model is also more accurate than FEMs built from mismatching individual anatomies. Our model is made available in Matlab format.

  2. Volume weighting the measure of the universe from classical slow-roll expansion

    Science.gov (United States)

    Sloan, David; Silk, Joseph

    2016-05-01

    One of the most frustrating issues in early universe cosmology centers on how to reconcile the vast choice of universes in string theory and in its most plausible high energy sibling, eternal inflation, which jointly generate the string landscape with the fine-tuned and hence relatively small number of universes that have undergone a large expansion and can accommodate observers and, in particular, galaxies. We show that such observations are highly favored for any system whereby physical parameters are distributed at a high energy scale, due to the conservation of the Liouville measure and the gauge nature of volume, asymptotically approaching a period of large isotropic expansion characterized by w =-1 . Our interpretation predicts that all observational probes for deviations from w =-1 in the foreseeable future are doomed to failure. The purpose of this paper is not to introduce a new measure for the multiverse, but rather to show how what is perhaps the most natural and well-known measure, volume weighting, arises as a consequence of the conservation of the Liouville measure on phase space during the classical slow-roll expansion.

  3. Method for sampling and analysis of volatile biomarkers in process gas from aerobic digestion of poultry carcasses using time-weighted average SPME and GC-MS.

    Science.gov (United States)

    Koziel, Jacek A; Nguyen, Lam T; Glanville, Thomas D; Ahn, Heekwon; Frana, Timothy S; Hans van Leeuwen, J

    2017-10-01

    A passive sampling method, using retracted solid-phase microextraction (SPME) - gas chromatography-mass spectrometry and time-weighted averaging, was developed and validated for tracking marker volatile organic compounds (VOCs) emitted during aerobic digestion of biohazardous animal tissue. The retracted SPME configuration protects the fragile fiber from buffeting by the process gas stream, and it requires less equipment and is potentially more biosecure than conventional active sampling methods. VOC concentrations predicted via a model based on Fick's first law of diffusion were within 6.6-12.3% of experimentally controlled values after accounting for VOC adsorption to the SPME fiber housing. Method detection limits for five marker VOCs ranged from 0.70 to 8.44ppbv and were statistically equivalent (p>0.05) to those for active sorbent-tube-based sampling. The sampling time of 30min and fiber retraction of 5mm were found to be optimal for the tissue digestion process. Copyright © 2017 Elsevier Ltd. All rights reserved.

  4. The weighted average cost of capital over the lifecycle of the firm: Is the overinvestment problem of mature firms intensified by a higher WACC?

    Directory of Open Access Journals (Sweden)

    Carlos S. Garcia

    2016-08-01

    Full Text Available Firm lifecycle theory predicts that the Weighted Average Cost of Capital (WACC will tend to fall over the lifecycle of the firm (Mueller, 2003, p. 80-81. However, given that previous research finds that corporate governance deteriorates as firms get older (Mueller and Yun, 1998; Saravia, 2014 there is good reason to suspect that the opposite could be the case, that is, that the WACC is higher for older firms. Since our literature review indicates that no direct tests to clarify this question have been carried out up till now, this paper aims to fill the gap by testing this prediction empirically. Our findings support the proposition that the WACC of younger firms is higher than that of mature firms. Thus, we find that the mature firm overinvestment problem is not intensified by a higher cost of capital, on the contrary, our results suggest that mature firms manage to invest in negative net present value projects even though they have access to cheaper capital. This finding sheds new light on the magnitude of the corporate governance problems found in mature firms.

  5. Improvement of internal tumor volumes of non-small cell lung cancer patients for radiation treatment planning using interpolated average CT in PET/CT.

    Directory of Open Access Journals (Sweden)

    Yao-Ching Wang

    Full Text Available Respiratory motion causes uncertainties in tumor edges on either computed tomography (CT or positron emission tomography (PET images and causes misalignment when registering PET and CT images. This phenomenon may cause radiation oncologists to delineate tumor volume inaccurately in radiotherapy treatment planning. The purpose of this study was to analyze radiology applications using interpolated average CT (IACT as attenuation correction (AC to diminish the occurrence of this scenario. Thirteen non-small cell lung cancer patients were recruited for the present comparison study. Each patient had full-inspiration, full-expiration CT images and free breathing PET images by an integrated PET/CT scan. IACT for AC in PET(IACT was used to reduce the PET/CT misalignment. The standardized uptake value (SUV correction with a low radiation dose was applied, and its tumor volume delineation was compared to those from HCT/PET(HCT. The misalignment between the PET(IACT and IACT was reduced when compared to the difference between PET(HCT and HCT. The range of tumor motion was from 4 to 17 mm in the patient cohort. For HCT and PET(HCT, correction was from 72% to 91%, while for IACT and PET(IACT, correction was from 73% to 93% (*p<0.0001. The maximum and minimum differences in SUVmax were 0.18% and 27.27% for PET(HCT and PET(IACT, respectively. The largest percentage differences in the tumor volumes between HCT/PET and IACT/PET were observed in tumors located in the lowest lobe of the lung. Internal tumor volume defined by functional information using IACT/PET(IACT fusion images for lung cancer would reduce the inaccuracy of tumor delineation in radiation therapy planning.

  6. Quantification of benzene, toluene, ethylbenzene and o-xylene in internal combustion engine exhaust with time-weighted average solid phase microextraction and gas chromatography mass spectrometry.

    Science.gov (United States)

    Baimatova, Nassiba; Koziel, Jacek A; Kenessov, Bulat

    2015-05-11

    A new and simple method for benzene, toluene, ethylbenzene and o-xylene (BTEX) quantification in vehicle exhaust was developed based on diffusion-controlled extraction onto a retracted solid-phase microextraction (SPME) fiber coating. The rationale was to develop a method based on existing and proven SPME technology that is feasible for field adaptation in developing countries. Passive sampling with SPME fiber retracted into the needle extracted nearly two orders of magnitude less mass (n) compared with exposed fiber (outside of needle) and sampling was in a time weighted-averaging (TWA) mode. Both the sampling time (t) and fiber retraction depth (Z) were adjusted to quantify a wider range of Cgas. Extraction and quantification is conducted in a non-equilibrium mode. Effects of Cgas, t, Z and T were tested. In addition, contribution of n extracted by metallic surfaces of needle assembly without SPME coating was studied. Effects of sample storage time on n loss was studied. Retracted TWA-SPME extractions followed the theoretical model. Extracted n of BTEX was proportional to Cgas, t, Dg, T and inversely proportional to Z. Method detection limits were 1.8, 2.7, 2.1 and 5.2 mg m(-3) (0.51, 0.83, 0.66 and 1.62 ppm) for BTEX, respectively. The contribution of extraction onto metallic surfaces was reproducible and influenced by Cgas and t and less so by T and by the Z. The new method was applied to measure BTEX in the exhaust gas of a Ford Crown Victoria 1995 and compared with a whole gas and direct injection method. Copyright © 2015 Elsevier B.V. All rights reserved.

  7. Modelling of an intermediate pressure microwave oxygen discharge reactor: from stationary two-dimensional to time-dependent global (volume-averaged) plasma models

    International Nuclear Information System (INIS)

    Kemaneci, Efe; Graef, Wouter; Rahimi, Sara; Van Dijk, Jan; Kroesen, Gerrit; Carbone, Emile; Jimenez-Diaz, Manuel

    2015-01-01

    A microwave-induced oxygen plasma is simulated using both stationary and time-resolved modelling strategies. The stationary model is spatially resolved and it is self-consistently coupled to the microwaves (Jimenez-Diaz et al 2012 J. Phys. D: Appl. Phys. 45 335204), whereas the time-resolved description is based on a global (volume-averaged) model (Kemaneci et al 2014 Plasma Sources Sci. Technol. 23 045002). We observe agreement of the global model data with several published measurements of microwave-induced oxygen plasmas in both continuous and modulated power inputs. Properties of the microwave plasma reactor are investigated and corresponding simulation data based on two distinct models shows agreement on the common parameters. The role of the square wave modulated power input is also investigated within the time-resolved description. (paper)

  8. Effects of Respiration-Averaged Computed Tomography on Positron Emission Tomography/Computed Tomography Quantification and its Potential Impact on Gross Tumor Volume Delineation

    International Nuclear Information System (INIS)

    Chi, Pai-Chun Melinda; Mawlawi, Osama; Luo Dershan; Liao Zhongxing; Macapinlac, Homer A.; Pan Tinsu

    2008-01-01

    Purpose: Patient respiratory motion can cause image artifacts in positron emission tomography (PET) from PET/computed tomography (CT) and change the quantification of PET for thoracic patients. In this study, respiration-averaged CT (ACT) was used to remove the artifacts, and the changes in standardized uptake value (SUV) and gross tumor volume (GTV) were quantified. Methods and Materials: We incorporated the ACT acquisition in a PET/CT session for 216 lung patients, generating two PET/CT data sets for each patient. The first data set (PET HCT /HCT) contained the clinical PET/CT in which PET was attenuation corrected with a helical CT (HCT). The second data set (PET ACT /ACT) contained the PET/CT in which PET was corrected with ACT. We quantified the differences between the two datasets in image alignment, maximum SUV (SUV max ), and GTV contours. Results: Of the patients, 68% demonstrated respiratory artifacts in the PET HCT , and for all patients the artifact was removed or reduced in the corresponding PET ACT . The impact of respiration artifact was the worst for lesions less than 50 cm 3 and located below the dome of the diaphragm. For lesions in this group, the mean SUV max difference, GTV volume change, shift in GTV centroid location, and concordance index were 21%, 154%, 2.4 mm, and 0.61, respectively. Conclusion: This study benchmarked the differences between the PET data with and without artifacts. It is important to pay attention to the potential existence of these artifacts during GTV contouring, as such artifacts may increase the uncertainties in the lesion volume and the centroid location

  9. Experimental validation of heterogeneity-corrected dose-volume prescription on respiratory-averaged CT images in stereotactic body radiotherapy for moving tumors

    International Nuclear Information System (INIS)

    Nakamura, Mitsuhiro; Miyabe, Yuki; Matsuo, Yukinori; Kamomae, Takeshi; Nakata, Manabu; Yano, Shinsuke; Sawada, Akira; Mizowaki, Takashi; Hiraoka, Masahiro

    2012-01-01

    The purpose of this study was to experimentally assess the validity of heterogeneity-corrected dose-volume prescription on respiratory-averaged computed tomography (RACT) images in stereotactic body radiotherapy (SBRT) for moving tumors. Four-dimensional computed tomography (CT) data were acquired while a dynamic anthropomorphic thorax phantom with a solitary target moved. Motion pattern was based on cos (t) with a constant respiration period of 4.0 sec along the longitudinal axis of the CT couch. The extent of motion (A 1 ) was set in the range of 0.0–12.0 mm at 3.0-mm intervals. Treatment planning with the heterogeneity-corrected dose-volume prescription was designed on RACT images. A new commercially available Monte Carlo algorithm of well-commissioned 6-MV photon beam was used for dose calculation. Dosimetric effects of intrafractional tumor motion were then investigated experimentally under the same conditions as 4D CT simulation using the dynamic anthropomorphic thorax phantom, films, and an ionization chamber. The passing rate of γ index was 98.18%, with the criteria of 3 mm/3%. The dose error between the planned and the measured isocenter dose in moving condition was within ± 0.7%. From the dose area histograms on the film, the mean ± standard deviation of the dose covering 100% of the cross section of the target was 102.32 ± 1.20% (range, 100.59–103.49%). By contrast, the irradiated areas receiving more than 95% dose for A 1 = 12 mm were 1.46 and 1.33 times larger than those for A 1 = 0 mm in the coronal and sagittal planes, respectively. This phantom study demonstrated that the cross section of the target received 100% dose under moving conditions in both the coronal and sagittal planes, suggesting that the heterogeneity-corrected dose-volume prescription on RACT images is acceptable in SBRT for moving tumors.

  10. Associations between age at first calving, rearing average daily weight gain, herd milk yield and dairy herd production, reproduction, and profitability.

    Science.gov (United States)

    Krpálková, L; Cabrera, V E; Kvapilík, J; Burdych, J; Crump, P

    2014-10-01

    The objective of this study was to evaluate the associations of variable intensity in rearing dairy heifers on 33 commercial dairy herds, including 23,008 cows and 18,139 heifers, with age at first calving (AFC), average daily weight gain (ADG), and milk yield (MY) level on reproduction traits and profitability. Milk yield during the production period was analyzed relative to reproduction and economic parameters. Data were collected during a 1-yr period (2011). The farms were located in 12 regions in the Czech Republic. The results show that those herds with more intensive rearing periods had lower conception rates among heifers at first and overall services. The differences in those conception rates between the group with the greatest ADG (≥0.800 kg/d) and the group with the least ADG (≤0.699 kg/d) were approximately 10 percentage points in favor of the least ADG. All the evaluated reproduction traits differed between AFC groups. Conception at first and overall services (cows) was greatest in herds with AFC ≥800 d. The shortest days open (105 d) and calving interval (396 d) were found in the middle AFC group (799 to 750 d). The highest number of completed lactations (2.67) was observed in the group with latest AFC (≥800 d). The earliest AFC group (≤749 d) was characterized by the highest depreciation costs per cow at 8,275 Czech crowns (US$414), and the highest culling rate for cows of 41%. The most profitable rearing approach was reflected in the middle AFC (799 to 750 d) and middle ADG (0.799 to 0.700 kg) groups. The highest MY (≥8,500 kg) occurred with the earliest AFC of 780 d. Higher MY led to lower conception rates in cows, but the highest MY group also had the shortest days open (106 d) and a calving interval of 386 d. The same MY group had the highest cow depreciation costs, net profit, and profitability without subsidies of 2.67%. We conclude that achieving low AFC will not always be the most profitable approach, which will depend upon farm

  11. High frequency oscillatory ventilation with lung volume optimization in very low birth weight newborns – a nine-year experience

    Directory of Open Access Journals (Sweden)

    José Nona

    2009-09-01

    Full Text Available Objective: To evaluate the clinical outcome of very low birth weight newborns, submitted to high frequency oscillatory ventilation with a strategy of early lung volume optimization. Methods: Descriptive prospective study in a nine-year period, between 1999 January 1st to 2008 January 1st. All the very low birth weight newborns were born in Dr. Alfredo da Costa Maternity, Lisbon, Portugal, were admitted to the Neonatal Intensive Care Unit and submitted to high frequency oscillatory ventilation with early lung volume optimization; these newborns were followed-up since birth and their charts were analyzed periodically until hospital discharge. Rresults: From a total population of 730 very low birth weight inborns, 117 babies died (16% and 613 survived (84%. The median of birth weight was 975 g and the gestational age median was 28 weeks. For the survivors, the median ventilation and oxygenation times were 3 and 18 days, respectively. The incidence of chronic lung disease was 9.5%, with nine newborns discharged on oxygen therapy. The incidence of intraventricular hemorrhage III – IV (total population group was 11.5% and the incidence of retinopathy of prematurity grade 3 or higher was 8.0%. Cconclusions: High frequency oscillatory ventilation with early lung volume optimization strategy reduced the need of respiratory support, and improved pulmonary and global outcomes in very low birth weight infants with respiratory distress syndrome.

  12. PET imaging of thin objects: measuring the effects of positron range and partial-volume averaging in the leaf of Nicotiana tabacum

    Energy Technology Data Exchange (ETDEWEB)

    Alexoff, David L., E-mail: alexoff@bnl.gov; Dewey, Stephen L.; Vaska, Paul; Krishnamoorthy, Srilalan; Ferrieri, Richard; Schueller, Michael; Schlyer, David J.; Fowler, Joanna S.

    2011-02-15

    Introduction: PET imaging in plants is receiving increased interest as a new strategy to measure plant responses to environmental stimuli and as a tool for phenotyping genetically engineered plants. PET imaging in plants, however, poses new challenges. In particular, the leaves of most plants are so thin that a large fraction of positrons emitted from PET isotopes ({sup 18}F, {sup 11}C, {sup 13}N) escape while even state-of-the-art PET cameras have significant partial-volume errors for such thin objects. Although these limitations are acknowledged by researchers, little data have been published on them. Methods: Here we measured the magnitude and distribution of escaping positrons from the leaf of Nicotiana tabacum for the radionuclides {sup 18}F, {sup 11}C and {sup 13}N using a commercial small-animal PET scanner. Imaging results were compared to radionuclide concentrations measured from dissection and counting and to a Monte Carlo simulation using GATE (Geant4 Application for Tomographic Emission). Results: Simulated and experimentally determined escape fractions were consistent. The fractions of positrons (mean{+-}S.D.) escaping the leaf parenchyma were measured to be 59{+-}1.1%, 64{+-}4.4% and 67{+-}1.9% for {sup 18}F, {sup 11}C and {sup 13}N, respectively. Escape fractions were lower in thicker leaf areas like the midrib. Partial-volume averaging underestimated activity concentrations in the leaf blade by a factor of 10 to 15. Conclusions: The foregoing effects combine to yield PET images whose contrast does not reflect the actual activity concentrations. These errors can be largely corrected by integrating activity along the PET axis perpendicular to the leaf surface, including detection of escaped positrons, and calculating concentration using a measured leaf thickness.

  13. Volume-weighted particle-tracking method for solute-transport modeling; Implementation in MODFLOW–GWT

    Science.gov (United States)

    Winston, Richard B.; Konikow, Leonard F.; Hornberger, George Z.

    2018-02-16

    In the traditional method of characteristics for groundwater solute-transport models, advective transport is represented by moving particles that track concentration. This approach can lead to global mass-balance problems because in models of aquifers having complex boundary conditions and heterogeneous properties, particles can originate in cells having different pore volumes and (or) be introduced (or removed) at cells representing fluid sources (or sinks) of varying strengths. Use of volume-weighted particles means that each particle tracks solute mass. In source or sink cells, the changes in particle weights will match the volume of water added or removed through external fluxes. This enables the new method to conserve mass in source or sink cells as well as globally. This approach also leads to potential efficiencies by allowing the number of particles per cell to vary spatially—using more particles where concentration gradients are high and fewer where gradients are low. The approach also eliminates the need for the model user to have to distinguish between “weak” and “strong” fluid source (or sink) cells. The new model determines whether solute mass added by fluid sources in a cell should be represented by (1) new particles having weights representing appropriate fractions of the volume of water added by the source, or (2) distributing the solute mass added over all particles already in the source cell. The first option is more appropriate for the condition of a strong source; the latter option is more appropriate for a weak source. At sinks, decisions whether or not to remove a particle are replaced by a reduction in particle weight in proportion to the volume of water removed. A number of test cases demonstrate that the new method works well and conserves mass. The method is incorporated into a new version of the U.S. Geological Survey’s MODFLOW–GWT solute-transport model.

  14. Repeatability of Brain Volume Measurements Made with the Atlas-based Method from T1-weighted Images Acquired Using a 0.4 Tesla Low Field MR Scanner.

    Science.gov (United States)

    Goto, Masami; Suzuki, Makoto; Mizukami, Shinya; Abe, Osamu; Aoki, Shigeki; Miyati, Tosiaki; Fukuda, Michinari; Gomi, Tsutomu; Takeda, Tohoru

    2016-10-11

    An understanding of the repeatability of measured results is important for both the atlas-based and voxel-based morphometry (VBM) methods of magnetic resonance (MR) brain volumetry. However, many recent studies that have investigated the repeatability of brain volume measurements have been performed using static magnetic fields of 1-4 tesla, and no study has used a low-strength static magnetic field. The aim of this study was to investigate the repeatability of measured volumes using the atlas-based method and a low-strength static magnetic field (0.4 tesla). Ten healthy volunteers participated in this study. Using a 0.4 tesla magnetic resonance imaging (MRI) scanner and a quadrature head coil, three-dimensional T 1 -weighted images (3D-T 1 WIs) were obtained from each subject, twice on the same day. VBM8 software was used to construct segmented normalized images [gray matter (GM), white matter (WM), and cerebrospinal fluid (CSF) images]. The regions-of-interest (ROIs) of GM, WM, CSF, hippocampus (HC), orbital gyrus (OG), and cerebellum posterior lobe (CPL) were generated using WFU PickAtlas. The percentage change was defined as[100 × (measured volume with first segmented image - mean volume in each subject)/(mean volume in each subject)]The average percentage change was calculated as the percentage change in the 6 ROIs of the 10 subjects. The mean of the average percentage changes for each ROI was as follows: GM, 0.556%; WM, 0.324%; CSF, 0.573%; HC, 0.645%; OG, 1.74%; and CPL, 0.471%. The average percentage change was higher for the orbital gyrus than for the other ROIs. We consider that repeatability of the atlas-based method is similar between 0.4 and 1.5 tesla MR scanners. To our knowledge, this is the first report to show that the level of repeatability with a 0.4 tesla MR scanner is adequate for the estimation of brain volume change by the atlas-based method.

  15. TH-E-BRE-03: A Novel Method to Account for Ion Chamber Volume Averaging Effect in a Commercial Treatment Planning System Through Convolution

    International Nuclear Information System (INIS)

    Barraclough, B; Li, J; Liu, C; Yan, G

    2014-01-01

    Purpose: Fourier-based deconvolution approaches used to eliminate ion chamber volume averaging effect (VAE) suffer from measurement noise. This work aims to investigate a novel method to account for ion chamber VAE through convolution in a commercial treatment planning system (TPS). Methods: Beam profiles of various field sizes and depths of an Elekta Synergy were collected with a finite size ion chamber (CC13) to derive a clinically acceptable beam model for a commercial TPS (Pinnacle 3 ), following the vendor-recommended modeling process. The TPS-calculated profiles were then externally convolved with a Gaussian function representing the chamber (σ = chamber radius). The agreement between the convolved profiles and measured profiles was evaluated with a one dimensional Gamma analysis (1%/1mm) as an objective function for optimization. TPS beam model parameters for focal and extra-focal sources were optimized and loaded back into the TPS for new calculation. This process was repeated until the objective function converged using a Simplex optimization method. Planar dose of 30 IMRT beams were calculated with both the clinical and the re-optimized beam models and compared with MapCHEC™ measurements to evaluate the new beam model. Results: After re-optimization, the two orthogonal source sizes for the focal source reduced from 0.20/0.16 cm to 0.01/0.01 cm, which were the minimal allowed values in Pinnacle. No significant change in the parameters for the extra-focal source was observed. With the re-optimized beam model, average Gamma passing rate for the 30 IMRT beams increased from 92.1% to 99.5% with a 3%/3mm criterion and from 82.6% to 97.2% with a 2%/2mm criterion. Conclusion: We proposed a novel method to account for ion chamber VAE in a commercial TPS through convolution. The reoptimized beam model, with VAE accounted for through a reliable and easy-to-implement convolution and optimization approach, outperforms the original beam model in standard IMRT QA

  16. The role of sodium-poly(acrylates) with different weight-average molar mass in phosphate-free laundry detergent builder systems

    OpenAIRE

    Milojević, Vladimir S.; Ilić-Stojanović, Snežana; Nikolić, Ljubiša; Nikolić, Vesna; Stamenković, Jakov; Stojiljković, Dragan

    2013-01-01

    In this study, the synthesis of sodium-poly(acrylate) was performed by polymerization of acrylic acid in the water solution with three different contents of potassium-persulphate as an initiator. The obtained polymers were characterized by using HPLC and GPC analyses in order to define the purity and average molar mass of poly(acrylic acid). In order to investigate the influence of sodium-poly(acrylate) as a part of carbonate/zeolite detergent builder system, secondary washing characteristics...

  17. Data Base for Light-Weight Automotive Diesel Power Plants. Volume 2: Discussion and Results.

    Science.gov (United States)

    1979-12-01

    The effects on fuel economy, emissions, passenger car safety and other variables due to the installation of light-weight Diesel powerplants were studied. Experimental data was obtained on naturally aspirated and turbocharged Diesel engines installed ...

  18. Data Base for Light-Weight Automotive Diesel Power Plants: Volume 1. Executive Summary.

    Science.gov (United States)

    1979-12-01

    The effects on fuel economy, emissions, passenger car safety and other variables due to the installation of light-weight Diesel powerplants were studied. Experimental data was obtained on naturally aspirated and turbocharged Diesel engines installed ...

  19. Data Base for Light-Weight Automotive Diesel Power Plants : Volume 3. Miscellaneous Data.

    Science.gov (United States)

    1979-12-01

    The effects of fuel economy, emissions, passenger car safety and other variables due to the installation of light-weight Diesel powerplants were studied. Experimental data was obtained on naturally aspirated and turbocharged Diesel engines installed ...

  20. The difference between alternative averages

    Directory of Open Access Journals (Sweden)

    James Vaupel

    2012-09-01

    Full Text Available BACKGROUND Demographers have long been interested in how compositional change, e.g., change in age structure, affects population averages. OBJECTIVE We want to deepen understanding of how compositional change affects population averages. RESULTS The difference between two averages of a variable, calculated using alternative weighting functions, equals the covariance between the variable and the ratio of the weighting functions, divided by the average of the ratio. We compare weighted and unweighted averages and also provide examples of use of the relationship in analyses of fertility and mortality. COMMENTS Other uses of covariances in formal demography are worth exploring.

  1. Technical Note: Impact of the geometry dependence of the ion chamber detector response function on a convolution-based method to address the volume averaging effect

    Energy Technology Data Exchange (ETDEWEB)

    Barraclough, Brendan; Lebron, Sharon [Department of Radiation Oncology, University of Florida, Gainesville, Florida 32608 and J. Crayton Pruitt Family Department of Biomedical Engineering, University of Florida, Gainesville, Florida 32611 (United States); Li, Jonathan G.; Fan, Qiyong; Liu, Chihray; Yan, Guanghua, E-mail: yangua@shands.ufl.edu [Department of Radiation Oncology, University of Florida, Gainesville, Florida 32608 (United States)

    2016-05-15

    Purpose: To investigate the geometry dependence of the detector response function (DRF) of three commonly used scanning ionization chambers and its impact on a convolution-based method to address the volume averaging effect (VAE). Methods: A convolution-based approach has been proposed recently to address the ionization chamber VAE. It simulates the VAE in the treatment planning system (TPS) by iteratively convolving the calculated beam profiles with the DRF while optimizing the beam model. Since the convolved and the measured profiles are subject to the same VAE, the calculated profiles match the implicit “real” ones when the optimization converges. Three DRFs (Gaussian, Lorentzian, and parabolic function) were used for three ionization chambers (CC04, CC13, and SNC125c) in this study. Geometry dependent/independent DRFs were obtained by minimizing the difference between the ionization chamber-measured profiles and the diode-measured profiles convolved with the DRFs. These DRFs were used to obtain eighteen beam models for a commercial TPS. Accuracy of the beam models were evaluated by assessing the 20%–80% penumbra width difference (PWD) between the computed and diode-measured beam profiles. Results: The convolution-based approach was found to be effective for all three ionization chambers with significant improvement for all beam models. Up to 17% geometry dependence of the three DRFs was observed for the studied ionization chambers. With geometry dependent DRFs, the PWD was within 0.80 mm for the parabolic function and CC04 combination and within 0.50 mm for other combinations; with geometry independent DRFs, the PWD was within 1.00 mm for all cases. When using the Gaussian function as the DRF, accounting for geometry dependence led to marginal improvement (PWD < 0.20 mm) for CC04; the improvement ranged from 0.38 to 0.65 mm for CC13; for SNC125c, the improvement was slightly above 0.50 mm. Conclusions: Although all three DRFs were found adequate to

  2. Improved longitudinal length accuracy of gross tumor volume delineation with diffusion weighted magnetic resonance imaging for esophageal squamous cell carcinoma

    International Nuclear Information System (INIS)

    Hou, Dong-Liang; Shi, Gao-Feng; Gao, Xian-Shu; Asaumi, Junichi; Li, Xue-Ying; Liu, Hui; Yao, Chen; Chang, Joe Y

    2013-01-01

    To analyze the longitudinal length accuracy of gross tumor volume (GTV) delineation with diffusion weighted magnetic resonance imaging for esophageal squamous cell carcinoma (SCC). Forty-two patients from December 2011 to June 2012 with esophageal SCC who underwent radical surgery were analyzed. Routine computed tomography (CT) scan, T2-weighted MRI and diffusion weighted magnetic resonance imaging (DWI) were employed before surgery. Diffusion-sensitive gradient b-values were taken at 400, 600, and 800 s/mm 2 . Gross tumor volumes (GTV) were delineated using CT, T2-weighted MRI and DWI on different b-value images. GTV longitude length measured using the imaging modalities listed above was compared with pathologic lesion length to determine the most accurate imaging modality. CMS Xio radiotherapy planning system was used to fuse DWI scans and CT images to investigate the possibility of delineating GTV on fused images. The differences between the GTV length according to CT, T2-weighted MRI and pathology were 3.63 ± 12.06 mm and 3.46 ± 11.41 mm, respectively. When the diffusion-sensitive gradient b-value was 400, 600, and 800 s/mm 2 , the differences between the GTV length using DWI and pathology were 0.73 ± 6.09 mm, -0.54 ± 6.03 mm and −1.58 ± 5.71 mm, respectively. DWI scans and CT images were fused accurately using the radiotherapy planning system. GTV margins were depicted clearly on fused images. DWI displays esophageal SCC lengths most precisely when compared with CT or regular MRI. DWI scans fused with CT images can be used to improve accuracy to delineate GTV in esophageal SCC

  3. Automation of registration of sample weights for high-volume neutron activation analysis at the IBR-2 reactor of FLNP, JINR

    International Nuclear Information System (INIS)

    Dmitriev, A.Yu.; Dmitriev, F.A.

    2015-01-01

    The 'Weight' software tool was created at FLNP JINR to automate the reading of analytical balance readouts and saving these values in the NAA database. The analytical balance connected to the personal computer is used to measure weight values. The 'Weight' software tool controls the reading of weight values and the exchange of information with the NAA database. The weighing process of a large amount of samples is reliably provided during high-volume neutron activation analysis. [ru

  4. CT- and MRI-based volumetry of resected liver specimen: Comparison to intraoperative volume and weight measurements and calculation of conversion factors

    International Nuclear Information System (INIS)

    Karlo, C.; Reiner, C.S.; Stolzmann, P.; Breitenstein, S.; Marincek, B.; Weishaupt, D.; Frauenfelder, T.

    2010-01-01

    Objective: To compare virtual volume to intraoperative volume and weight measurements of resected liver specimen and calculate appropriate conversion factors to reach better correlation. Methods: Preoperative (CT-group, n = 30; MRI-group, n = 30) and postoperative MRI (n = 60) imaging was performed in 60 patients undergoing partial liver resection. Intraoperative volume and weight of the resected liver specimen was measured. Virtual volume measurements were performed by two readers (R1,R2) using dedicated software. Conversion factors were calculated. Results: Mean intraoperative resection weight/volume: CT: 855 g/852 mL; MRI: 872 g/860 mL. Virtual resection volume: CT: 960 mL(R1), 982 mL(R2); MRI: 1112 mL(R1), 1115 mL(R2). Strong positive correlation for both readers between intraoperative and virtual measurements, mean of both readers: CT: R = 0.88(volume), R = 0.89(weight); MRI: R = 0.95(volume), R = 0.92(weight). Conversion factors: 0.85(CT), 0.78(MRI). Conclusion: CT- or MRI-based volumetry of resected liver specimen is accurate and recommended for preoperative planning. A conversion of the result is necessary to improve intraoperative and virtual measurement correlation. We found 0.85 for CT- and 0.78 for MRI-based volumetry the most appropriate conversion factors.

  5. Prediction of infarction and reperfusion in stroke by flow- and volume-weighted collateral signal in MR angiography.

    Science.gov (United States)

    Ernst, M; Forkert, N D; Brehmer, L; Thomalla, G; Siemonsen, S; Fiehler, J; Kemmling, A

    2015-02-01

    In proximal anterior circulation occlusive strokes, collateral flow is essential for good outcome. Collateralized vessel intensity in TOF- and contrast-enhanced MRA is variable due to different acquisition methods. Our purpose was to quantify collateral supply by using flow-weighted signal in TOF-MRA and blood volume-weighted signal in contrast-enhanced MRA to determine each predictive contribution to tissue infarction and reperfusion. Consecutively (2009-2013), 44 stroke patients with acute proximal anterior circulation occlusion met the inclusion criteria with TOF- and contrast-enhanced MRA and penumbral imaging. Collateralized vessels in the ischemic hemisphere were assessed by TOF- and contrast-enhanced MRA using 2 methods: 1) visual 3-point collateral scoring, and 2) collateral signal quantification by an arterial atlas-based collateral index. Collateral measures were tested by receiver operating characteristic curve and logistic regression against 2 imaging end points of tissue-outcome: final infarct volume and percentage of penumbra saved. Visual collateral scores on contrast-enhanced MRA but not TOF were significantly higher in patients with good outcome. Visual collateral scoring on contrast-enhanced MRA was the best rater-based discriminator for final infarct volume 50% (area under the curve, 0.67; P = .04). Atlas-based collateral index of contrast-enhanced MRA was the overall best independent discriminator for final infarct volume of collateral index combining the signal of TOF- and contrast-enhanced MRA was the overall best discriminator for effective reperfusion (percentage of penumbra saved >50%; area under the curve, 0.89; P collateral assessment, TOF- and contrast-enhanced MRA both contain predictive signal information for penumbral reperfusion. This could improve risk stratification in further studies. © 2015 by American Journal of Neuroradiology.

  6. Soil weight (lbf/ft3) at Hanford waste storage locations (2 volumes)

    International Nuclear Information System (INIS)

    Pianka, E.W.

    1994-12-01

    Hanford Reservation waste storage tanks are fabricated in accordance with approved construction specifications. After an underground tank has been constructed in the excavation prepared for it, soil is place around the tank and compacted by an approved compaction procedure. To ensure compliance with the construction specifications, measurements of the soil compaction are taken by QA inspectors using test methods based on American Society for the Testing and Materials (ASTM) standards. Soil compaction tests data taken for the 241AP, 241AN, and 241AW tank farms constructed between 1978 and 1986 are included. The individual data values have been numerically processed to obtain average soil density values for each of these tank farms

  7. Feasibility study of modern airships, phase 1. Volume 2: Parametric analysis (task 3). [lift, weight (mass)

    Science.gov (United States)

    Lancaster, J. W.

    1975-01-01

    Various types of lighter-than-air vehicles from fully buoyant to semibuoyant hybrids were examined. Geometries were optimized for gross lifting capabilities for ellipsoidal airships, modified delta planform lifting bodies, and a short-haul, heavy-lift vehicle concept. It is indicated that: (1) neutrally buoyant airships employing a conservative update of materials and propulsion technology provide significant improvements in productivity; (2) propulsive lift for VTOL and aerodynamic lift for cruise significantly improve the productivity of low to medium gross weight ellipsoidal airships; and (3) the short-haul, heavy-lift vehicle, consisting of a simple combination of an ellipsoidal airship hull and existing helicopter componentry, provides significant potential for low-cost, near-term applications for ultra-heavy lift missions.

  8. Birth weight differences between those offered financial voucher incentives for verified smoking cessation and control participants enrolled in the Cessation in Pregnancy Incentives Trial (CPIT), employing an intuitive approach and a Complier Average Causal Effects (CACE) analysis.

    Science.gov (United States)

    McConnachie, Alex; Haig, Caroline; Sinclair, Lesley; Bauld, Linda; Tappin, David M

    2017-07-20

    The Cessation in Pregnancy Incentives Trial (CPIT), which offered financial incentives for smoking cessation during pregnancy showed a clinically and statistically significant improvement in cessation. However, infant birth weight was not seen to be affected. This study re-examines birth weight using an intuitive and a complier average causal effects (CACE) method to uncover important information missed by intention-to-treat analysis. CPIT offered financial incentives up to £400 to pregnant smokers to quit. With incentives, 68 women (23.1%) were confirmed non-smokers at primary outcome, compared to 25 (8.7%) without incentives, a difference of 14.3% (Fisher test, p financial incentives to quit. Viewed in this way, the overall birth weight gain with incentives is attributable only to potential quitters. We compared an intuitive approach to a CACE analysis. Mean birth weight of potential quitters in the incentives intervention group (who therefore quit) was 3338 g compared with potential quitters in the control group (who did not quit) 3193 g. The difference attributable to incentives, was 3338 - 3193 = 145 g (95% CI -617, +803). The mean difference in birth weight between the intervention and control groups was 21 g, and the difference in the proportion who managed to quit was 14.3%. Since the intervention consisted of the offer of incentives to quit smoking, the intervention was received by all women in the intervention group. However, "compliance" was successfully quitting with incentives, and the CACE analysis yielded an identical result, causal birth weight increase 21 g ÷ 0.143 = 145 g. Policy makers have great difficulty giving pregnant women money to stop smoking. This study indicates that a small clinically insignificant improvement in average birth weight is likely to hide an important clinically significant increase in infants born to pregnant smokers who want to stop but cannot achieve smoking cessation without the addition of financial

  9. Weighted-Average Least Squares Prediction

    NARCIS (Netherlands)

    Magnus, Jan R.; Wang, Wendun; Zhang, Xinyu

    2016-01-01

    Prediction under model uncertainty is an important and difficult issue. Traditional prediction methods (such as pretesting) are based on model selection followed by prediction in the selected model, but the reported prediction and the reported prediction variance ignore the uncertainty from the

  10. Development of realistic high-resolution whole-body voxel models of Japanese adult males and females of average height and weight, and application of models to radio-frequency electromagnetic-field dosimetry

    International Nuclear Information System (INIS)

    Nagaoka, Tomoaki; Watanabe, Soichi; Sakurai, Kiyoko; Kunieda, Etsuo; Watanabe, Satoshi; Taki, Masao; Yamanaka, Yukio

    2004-01-01

    With advances in computer performance, the use of high-resolution voxel models of the entire human body has become more frequent in numerical dosimetries of electromagnetic waves. Using magnetic resonance imaging, we have developed realistic high-resolution whole-body voxel models for Japanese adult males and females of average height and weight. The developed models consist of cubic voxels of 2 mm on each side; the models are segmented into 51 anatomic regions. The adult female model is the first of its kind in the world and both are the first Asian voxel models (representing average Japanese) that enable numerical evaluation of electromagnetic dosimetry at high frequencies of up to 3 GHz. In this paper, we will also describe the basic SAR characteristics of the developed models for the VHF/UHF bands, calculated using the finite-difference time-domain method

  11. The application value of diffusion-weighted magnetic resonance imaging in gross tumor volume delineation of esophageal squamous cell carcinoma

    International Nuclear Information System (INIS)

    Hou Dongliang; Shi Gaofeng; Gao Xianshu

    2012-01-01

    Objective: To analyze the application value of diffusion-weighted magnetic resonance imaging (DWMRI) in gross tumor volume (GTV) delineation of esophageal squamous cell carcinoma (SCC). Methods: Twenty-nine patients with esophageal SCC treated with radical surgery were analyzed. Routine CT scan, MRI T 2 -weighted and DWMRI were employed before surgery; diffusion-sensitive gradient b-values were taken 400, 600 and 800 s/mm 2 . GTVs were delineated using CT, MRI T 2 -weighted images and DWMRI under different b-value images. The length of GTVs measured under different images was compared with the pathological length and confirm the most accurate imaging condition. Use radiotherapy planning system to fuse DWMRI images and CT images to investigate the possibility of delineate GTVs on fused images. Results: The difference of GTV length value between CT, T 2 WI images and specimen was 3.36 mm and 2.84 mm. When b =400,600 and 800 s/mm 2 , the difference between GTV length value on the DWMRI images and on specimen was 0.47 mm, -0.47 mm and - 1.53 mm; the correlation coefficient of the measuring esophageal lengths on DWMRI images and the pathological lengths was 0.928, 0.927 and 0.938. DWMRI images and CT images could fuse accurately on radiotherapy planning system. GTV margin could.show clearly on fused images. Conclusions: DWMRI images can display the esophageal carcinoma lengths and margin accurately. When DWMRI images fused with CT images, GTV margin could show clearly,it can be used to delineate GTV accurately. (authors)

  12. Characterization of Volume F Trash from the Three FY11 STS Missions: Trash Weights and Categorization and Microbial Characterization

    Science.gov (United States)

    Strayer, Richard F.; Hummerick, Mary E.; Richards, Jeffrey T.; McCoy, LaShelle E.; Roberts, Michael S.; Wheller, Raymond M.

    2011-01-01

    The project reported here provides microbial characterization support to the Waste Management Systems (WMS) element of NASA's Life Support and Habitation Systems (LSHS) program. Conventional microbiological methods were used to detect and enumerate microorganisms in STS Volume F Compartment trash for three shuttle missions: STS 133, 134, and 135. This trash was usually made available within 2 days of landing at KSC. The Volume F bag was weighed, opened and the contents were cataloged and placed into categories: personal hygiene items - inclUding EVA maximum absorbent garments (MAGs) and Elbow packs (daily toilet wipes, etc), drink containers, food waste (and containers), office waste (paper), and packaging materials - plastic film and duct tape. The average wet trash generation rate for the three STS missions was 0.362 % 0.157 kgwet crew 1 d-1 . This was considerably lower and more variable than the average rate for 4 STS missions reported for FY10. Trash subtotals by category: personal hygiene wastes, 56%; drink items, 11 %; food wastes, 18%; office waste, 3%; and plastic film, 12%. These wastes have an abundance of easily biodegraded compounds that can support the growth of microorganisms. Microbial characterization of trash showed that large numbers of bacteria and fungi have taken advantage of this readily available nutrient source to proliferate. Exterior and interior surfaces of plastic film bags containing trash were sampled and counts of cultivatable microbes were generally low and mostly occurred on trash bundles within the exterior trash bags. Personal hygiene wastes, drink containers, and food wastes and packaging all contained high levels of, mostly, aerobic heterotrophic bacteria and lower levels of yeasts and molds. Isolates from plate count media were obtained and identified .and were mostly aerobic heterotrophs with some facultative anaerobes. These are usually considered common environmental isolates on Earth. However, several pathogens were also

  13. The Partial Molar Volume and Thermal Expansivity of Fe2O3 in Alkali Silicate Liquids: Evidence for the Average Coordination of Fe3+

    Science.gov (United States)

    Liu, Q.; Lange, R.

    2003-12-01

    Ferric iron is an important component in magmatic liquids, especially in those formed at subduction zones. Although it has long been known that Fe3+ occurs in four-, five- and six-fold coordination in crystalline compounds, only recently have all three Fe3+ coordination sites been confirmed in silicate glasses utilizing XANES spectroscopy at the Fe K-edge (Farges et al., 2003). Because the density of a magmatic liquid is largely determined by the geometrical packing of its network-forming cations (e.g., Si4+, Al3+, Ti4+, and Fe3+), the capacity of Fe3+ to undergo composition-induced coordination change affects the partial molar volume of the Fe2O3 component, which must be known to calculate how the ferric-ferrous ratio in magmatic liquids changes with pressure. Previous work has shown that the partial molar volume of Fe2O3 (VFe2O3) varies between calcic vs. sodic silicate melts (Mo et al., 1982; Dingwell and Brearley, 1988; Dingwell et al., 1988). The purpose of this study is to extend the data set in order to search for systematic variations in VFe2O3 with melt composition. High temperature (867-1534° C) density measurements were performed on eleven liquids in the Na2O-Fe2O3-FeO-SiO2 (NFS) system and five liquids in the K2O-Fe2O3-FeO-SiO2 (KFS) system using Pt double-bob Archimedean method. The ferric-ferrous ratio in the sodic and potassic liquids at each temperature of density measurement were calculated from the experimentally calibrated models of Lange and Carmichael (1989) and Tangeman et al. (2001) respectively. Compositions range (in mol%) from 4-18 Fe2O3, 0-3 FeO, 12-39 Na2O, 25-37 K2O, and 43-78 SiO2. Our density data are consistent with those of Dingwell et al. (1988) on similar sodic liquids. Our results indicate that for all five KFS liquids and for eight of eleven NFS liquids, the partial molar volume of the Fe2O3 component is a constant (41.57 ñ 0.14 cm3/mol) and exhibits zero thermal expansivity (similar to that for the SiO2 component). This value

  14. Relationship between partial and average atomic volumes of components in Au-Ni alloys%Au-Ni合金中组元的平均原子体积和偏摩尔体积的关系

    Institute of Scientific and Technical Information of China (English)

    谢佑卿

    2011-01-01

    在系统合金科学框架中建立有关无序合金的平均摩尔性质(体积和势能)的函数.通过对这些函数进行推导,可以得到平均摩尔体积函数、偏摩尔体积函数及派生出与成分相关的函数.在组元的偏摩尔性质和平均摩尔性质之间的普适方程、差分方程、在偏摩尔性质和平均摩尔性质之间不同参数的约束方程和普适的Gibbs-Duhem公式.可以证明从合金平均摩尔性质的不同函数计算的偏摩尔性质是相等的,但总体来说偏摩尔性质不等于给定组元的平均摩尔性质,即偏摩尔性质不能代表相应组元的摩尔性质.通过计算Au-Ni系中组元的偏摩尔体积和平均原子体积以及合金的平均原子体积,证明所建立的公式和函数的正确性.%In the framework of systematic science of alloys,the average molar property (volume and potential energy) functions of disordered alloys were established.From these functions,the average molar property functions,partial molar property functions,derivative functions with respect to composition,general equation of relationship between partial and average molar properties of components,difference equation and constraining equation of different values between partial and average molar properties,as well as general Gibbs-Duhem formula were derived.It was proved that the partial molar properties calculated from various combinative functions of average molar properties of alloys are equal,but in general,the partial molar properties are not equal to the average molar properties of a given component.This means that the partial molar properties cannot represent the corresponding properties of the component.All the equations and functions established in this work were proved to be correct by calculating the results of partial and average atomic volumes of components as well as average atomic volumes of alloys in the Au-Ni system.

  15. Muscle Volume Increases Following 16 Weeks of Resistive Exercise Training with the Advanced Resistive Exercise Device (ARED) and Free Weights

    Science.gov (United States)

    Nash, R. E.; Loehr, J. A.; Lee, S. M. C.; English, K. L.; Evans, H.; Smith, S. A.; Hagan, R. D.

    2009-01-01

    Space flight-induced muscle atrophy, particularly in the postural and locomotorymuscles, may impair task performance during long-duration space missions and planetary exploration. High intensity free weight (FW) resistive exercise training has been shown to prevent atrophy during bed rest, a space flight analog. NASA developed the Advanced Resistive Exercise Device (ARED) to simulate the characteristics of FW exercise (i.e. constant mass, inertial force) and to be used as a countermeasure during International Space Station (ISS) missions. PURPOSE: To compare the efficacy of ARED and FW training to induce hypertrophy in specific muscle groups in ambulatory subjects prior to deploying ARED on the ISS. METHODS: Twenty untrained subjects were assigned to either the ARED (8 males, 3 females) or FW (6 males, 3 females) group and participated in a periodizedtraining protocol consisting of squat (SQ), heel raise (HR), and deadlift(DL) exercises 3 d wk-1 for 16 wks. SQ, HR, and DL muscle strength (1RM) was measured before, after 8 wks, and after 16 wks of training to prescribe exercise and measure strength changes. Muscle volume of the vastigroup (V), hamstring group (H), hip adductor group (ADD), medial gastrocnemius(MG), lateral gastrocnemius(LG), and deep posterior muscles including soleus(DP) was measured using MRI pre-and post-training. Consecutive cross-sectional images (8 mm slices with a 2 mm gap) were analyzed and summed. Anatomical references insured that the same muscle sections were analyzed pre-and post-training. Two-way repeated measures ANOVAs (ptraining devices. RESULTS: SQ, HR, and DL 1RM increased in both FW (SQ: 49+/-6%, HR: 12+/-2%, DL: 23+/-4%) and ARED (SQ: 31+/-4%, HR: 18+/-2%, DL: 23+/-3%) groups. Both groups increased muscle volume in the V (FW: 13+/-2%, ARED: 10+/-2%), H (FW: 3+/-1%, ARED: 3+/-1 %), ADD (FW: 15=/-2%, ARED: 10+/-1%), LG (FW: 7+/-2%, ARED: 4+/-1%), MG (FW: 7+/-2%, ARED: 5+/-2%), and DP (FW: 2+/-1%; ARED: 2+/-1%) after training. There

  16. Cell-Averaged discretization for incompressible Navier-Stokes with embedded boundaries and locally refined Cartesian meshes: a high-order finite volume approach

    Science.gov (United States)

    Bhalla, Amneet Pal Singh; Johansen, Hans; Graves, Dan; Martin, Dan; Colella, Phillip; Applied Numerical Algorithms Group Team

    2017-11-01

    We present a consistent cell-averaged discretization for incompressible Navier-Stokes equations on complex domains using embedded boundaries. The embedded boundary is allowed to freely cut the locally-refined background Cartesian grid. Implicit-function representation is used for the embedded boundary, which allows us to convert the required geometric moments in the Taylor series expansion (upto arbitrary order) of polynomials into an algebraic problem in lower dimensions. The computed geometric moments are then used to construct stencils for various operators like the Laplacian, divergence, gradient, etc., by solving a least-squares system locally. We also construct the inter-level data-transfer operators like prolongation and restriction for multi grid solvers using the same least-squares system approach. This allows us to retain high-order of accuracy near coarse-fine interface and near embedded boundaries. Canonical problems like Taylor-Green vortex flow and flow past bluff bodies will be presented to demonstrate the proposed method. U.S. Department of Energy, Office of Science, ASCR (Award Number DE-AC02-05CH11231).

  17. Bone marrow response in treated patients with Gaucher disease: evaluation by T1-weighted magnetic resonance images and correlation with reduction in liver and spleen volume

    International Nuclear Information System (INIS)

    Terk, M.R.; Dardashti, S.; Liebman, H.A.

    2000-01-01

    Purpose. To determine whether T1-weighted magnetic resonance (MR) images can demonstrate response in the marrow of patients with type 1 Gaucher disease treated with enzyme replacement therapy (ERT) and to determine whether a relationship exists between liver and spleen volume reductions and visible marrow changes.Patients. Forty-two patients with type 1 Gaucher disease were evaluated on at least two occasions. Thirty-two patients received ERT. Of these patients, 15 had a baseline examination prior to the initiation of ERT. The remaining 10 patients did not receive ERT.Design. T1-weighted and gradient recalled echo (GRE) coronal images of the femurs and hips were obtained. Concurrently, liver and spleen volumes were determined using contiguous breath-hold axial gradient-echo images. T1-weighted images of the hips and femurs were evaluated to determine change or lack of change in the yellow marrow.Results. Of the 32 patients receiving ERT, 14 (44%) demonstrated increased signal on T1-weighted images suggesting an increase in the amount of yellow marrow. If only the 15 patients with a baseline examination were considered, the response rate to ERT was 67%. Using Student's t-test a highly significant correlation (P<0.005) was found between marrow response and reduction in liver and spleen volume.Conclusions. Marrow changes in patients receiving ERT can be detected by T1-weighted images. This response correlated with reductions in visceral volumes (P<0.0005). (orig.)

  18. Measurement of flux-weighted average cross-sections and isomeric yield ratios for {sup 103}Rh(γ, xn) reactions in the bremsstrahlung end-point energies of 55 and 60 MeV

    Energy Technology Data Exchange (ETDEWEB)

    Shakilur Rahman, Md.; Kim, Kwangsoo; Kim, Guinyun; Nadeem, Muhammad; Thi Hien, Nguyen; Shahid, Muhammad [Kyungpook National University, Department of Physics, Daegu (Korea, Republic of); Naik, Haladhara [Bhabha Atomic Research Centre, Radiochemistry Division, Mumbai (India); Yang, Sung-Chul; Cho, Young-Sik; Lee, Young-Ouk [Korea Atomic Energy Research Institute, Nuclear Data Center, Daejeon (Korea, Republic of); Shin, Sung-Gyun; Cho, Moo-Hyun [Pohang University of Science and Technology, Division of Advanced Nuclear Engineering, Pohang (Korea, Republic of); Woo Lee, Man; Kang, Yeong-Rok; Yang, Gwang-Mo [Dongnam Institute of Radiological and Medical Science, Research Center, Busan (Korea, Republic of); Ro, Tae-Ik [Dong-A University, Department of Materials Physics, Busan (Korea, Republic of)

    2016-07-15

    We measured the flux-weighted average cross-sections and the isomeric yield ratios of {sup 99m,g,100m,g,101m,g,102m,g}Rh in the {sup 103}Rh(γ, xn) reactions with the bremsstrahlung end-point energies of 55 and 60 MeV by the activation and the off-line γ-ray spectrometric technique, using the 100 MeV electron linac at the Pohang Accelerator Laboratory (PAL), Korea. The flux-weighted average cross-sections were calculated by using the computer code TALYS 1.6 based on mono-energetic photons, and compared with the present experimental data. The flux-weighted average cross-sections of {sup 103}Rh(γ, xn) reactions in intermediate bremsstrahlung energies are the first time measurement and are found to increase from their threshold value to a particular value, where the other reaction channels open up. Thereafter, it decreases with bremsstrahlung energy due to its partition in different reaction channels. The isomeric yield ratios (IR) of {sup 99m,g,100m,g,101m,g,102m,g}Rh in the {sup 103}Rh(γ, xn) reactions from the present work were compared with the literature data in the {sup 103}Rh(d, x), {sup 102-99}Ru(p, x), {sup 103}Rh(α, αn), {sup 103}Rh(α, 2p3n), {sup 102}Ru({sup 3}He, x), and {sup 103}Rh(γ, xn) reactions. It was found that the IR values of {sup 102,101,100,99}Rh in all these reactions increase with the projectile energy, which indicates the role of excitation energy. At the same excitation energy, the IR values of {sup 102,101,100,99}Rh are higher in the charged particle-induced reactions than in the photon-induced reaction, which indicates the role of input angular momentum. (orig.)

  19. 3D Volumetry and its Correlation Between Postoperative Gastric Volume and Excess Weight Loss After Sleeve Gastrectomy.

    Science.gov (United States)

    Hanssen, Andrés; Plotnikov, Sergio; Acosta, Geylor; Nuñez, José Tomas; Haddad, José; Rodriguez, Carmen; Petrucci, Claudia; Hanssen, Diego; Hanssen, Rafael

    2018-03-01

    The volume of the postoperative gastric remnant is a key factor in excess weight loss (EWL) after sleeve gastrectomy (SG). Traditional methods to estimate gastric volume (GV) after bariatric procedures are often inaccurate; usually conventional biplanar contrast studies are used. Thirty patients who underwent SG were followed prospectively and evaluated at 6 months after the surgical procedure, performing 3D CT reconstruction and gastric volumetry, to establish its relationship with EWL. The gastric remnant was distended with effervescent sodium bicarbonate given orally. Helical CT images were acquired and reconstructed; GV was estimated with the software of the CT device. The relationship between GV and EWL was analyzed. The study allowed estimating the GV in all patients. A dispersion diagram showed an inverse relationship between GV and %EWL. 55.5% of patients with GV ≤ 100 ml had %EWL 25-75% and 38.8% had an %EWL above 75% and patients with GV ≥ 100 ml had an %EWL under 25% (50% of patients) or between 25 and 75% (50% of this group). The Pearson's correlation coefficient was R = 6.62, with bilateral significance (p ≤ .01). The Chi-square result correlating GV and EWL showed a significance of .005 (p ≤ .01). The 3D reconstructions showed accurately the shape and anatomic details of the gastric remnant. 3D volumetry CT scans accurately estimate GV after SG. A significant relationship between GV and EWL 6 months after SG was established, seeming that GV ≥ 100 ml at 6 months of SG is associated with poor EWL.

  20. Strain and sex differences in puberty onset and the effects of THC administration on weight gain and brain volumes.

    Science.gov (United States)

    Keeley, R J; Trow, J; McDonald, R J

    2015-10-01

    The use of recreational marijuana is widespread and frequently begins and persists through adolescence. Some research has shown negative consequences of adolescent marijuana use, but this is not seen across studies, and certain factors, like genetic background and sex, may influence the results. It is critical to identify which characteristics predispose an individual to be susceptible to the negative consequences of chronic exposure to marijuana in adolescence on brain health and behavior. To this end, using males and females of two strains of rats, Long-Evans hooded (LER) and Wistar (WR) rats, we explored whether these anatomically and behaviorally dimorphic strains demonstrated differences in puberty onset and strain-specific effects of adolescent exposure to Δ9-tetrahydrocannabinol (THC), the main psychoactive component of marijuana. Daily 5 mg/kg treatment began on the day of puberty onset and continued for 14 days. Of particular interest were metrics of growth and volumetric estimates of brain areas involved in cognition that contain high densities of cannabinoid receptors, including the hippocampus and its subregions, the amygdala, and the frontal cortex. Brain volumetrics were analyzed immediately following the treatment period. LER and WR females started puberty at different ages, but no strain differences were observed in brain volumes. THC decreased weight gain throughout the treatment period for all groups. Only the hippocampus and some of its subregions were affected by THC, and increased volumes with THC administration was observed exclusively in females, regardless of strain. Long-term treatment of THC did not affect all individuals equally, and females displayed evidence of increased sensitivity to the effects of THC, and by extension, marijuana. Identifying differences in adolescent physiology of WR and LER rats could help determine the cause for strain and sex differences in brain and behavior of adults and help to refine the use of animal models

  1. Batch medication of intestinal infections in nursery pigs—A randomised clinical trial on the efficacy of treatment strategy, type of antibiotic and bacterial load on average daily weight gain

    DEFF Research Database (Denmark)

    Weber, Nicolai Rosager; Pedersen, Ken Steen; Hansen, Christian Fink

    2017-01-01

    after weaning) on average daily weight gain (ADG); (2) to compare the effect of treatment with doxycycline or tylosine on diarrhoea prevalence, pathogenic bacterial load, and ADG; (3) to evaluate PCR testing of faecal pen floor samples as a diagnostic tool for determining the optimal time of treatment...... difference (p = 0.04) of mean diarrhoea prevalence on day 21 of the study between pens treated with tylosine (0.254, 95% CI: 0.184–0.324), and doxycycline (0.167, 95% CI: 0.124–0.210). The type of antibiotic compound was not found to have a significant effect on ADG (p = 0.209). (3) Pigs starting treatment...... was achieved when treatment was initiated 14 days after weaning in pens where intestinal pathogens were detected. Doxycycline was more effective in reducing diarrhoea and LI excretion levels than treatment with tylosine....

  2. Automated and Semiautomated Segmentation of Rectal Tumor Volumes on Diffusion-Weighted MRI: Can It Replace Manual Volumetry?

    International Nuclear Information System (INIS)

    Heeswijk, Miriam M. van; Lambregts, Doenja M.J.; Griethuysen, Joost J.M. van; Oei, Stanley; Rao, Sheng-Xiang; Graaff, Carla A.M. de; Vliegen, Roy F.A.; Beets, Geerard L.; Papanikolaou, Nikos; Beets-Tan, Regina G.H.

    2016-01-01

    Purpose: Diffusion-weighted imaging (DWI) tumor volumetry is promising for rectal cancer response assessment, but an important drawback is that manual per-slice tumor delineation can be highly time consuming. This study investigated whether manual DWI-volumetry can be reproduced using a (semi)automated segmentation approach. Methods and Materials: Seventy-nine patients underwent magnetic resonance imaging (MRI) that included DWI (highest b value [b1000 or b1100]) before and after chemoradiation therapy (CRT). Tumor volumes were assessed on b1000 (or b1100) DWI before and after CRT by means of (1) automated segmentation (by 2 inexperienced readers), (2) semiautomated segmentation (manual adjustment of the volumes obtained by method 1 by 2 radiologists), and (3) manual segmentation (by 2 radiologists); this last assessment served as the reference standard. Intraclass correlation coefficients (ICC) and Dice similarity indices (DSI) were calculated to evaluate agreement between different methods and observers. Measurement times (from a radiologist's perspective) were recorded for each method. Results: Tumor volumes were not significantly different among the 3 methods, either before or after CRT (P=.08 to .92). ICCs compared to manual segmentation were 0.80 to 0.91 and 0.53 to 0.66 before and after CRT, respectively, for the automated segmentation and 0.91 to 0.97 and 0.61 to 0.75, respectively, for the semiautomated method. Interobserver agreement (ICC) pre and post CRT was 0.82 and 0.59 for automated segmentation, 0.91 and 0.73 for semiautomated segmentation, and 0.91 and 0.75 for manual segmentation, respectively. Mean DSI between the automated and semiautomated method were 0.83 and 0.58 pre-CRT and post-CRT, respectively; DSI between the automated and manual segmentation were 0.68 and 0.42 and 0.70 and 0.41 between the semiautomated and manual segmentation, respectively. Median measurement time for the radiologists was 0 seconds (pre- and post-CRT) for the

  3. Automated and Semiautomated Segmentation of Rectal Tumor Volumes on Diffusion-Weighted MRI: Can It Replace Manual Volumetry?

    Energy Technology Data Exchange (ETDEWEB)

    Heeswijk, Miriam M. van [Department of Radiology, Maastricht University Medical Centre, Maastricht (Netherlands); Department of Surgery, Maastricht University Medical Centre, Maastricht (Netherlands); Lambregts, Doenja M.J., E-mail: d.lambregts@nki.nl [Department of Radiology, Maastricht University Medical Centre, Maastricht (Netherlands); Department of Radiology, The Netherlands Cancer Institute, Amsterdam (Netherlands); Griethuysen, Joost J.M. van [GROW School for Oncology and Developmental Biology, Maastricht University Medical Centre, Maastricht (Netherlands); Department of Radiology, The Netherlands Cancer Institute, Amsterdam (Netherlands); Oei, Stanley [Department of Radiology, Maastricht University Medical Centre, Maastricht (Netherlands); Rao, Sheng-Xiang [Department of Radiology, Maastricht University Medical Centre, Maastricht (Netherlands); Department of Radiology, Zhongshan Hospital, Fudan University, Shanghai (China); Graaff, Carla A.M. de [Department of Radiology, Maastricht University Medical Centre, Maastricht (Netherlands); Vliegen, Roy F.A. [Atrium Medical Centre Parkstad/Zuyderland Medical Centre, Heerlen (Netherlands); Beets, Geerard L. [GROW School for Oncology and Developmental Biology, Maastricht University Medical Centre, Maastricht (Netherlands); Department of Surgery, The Netherlands Cancer Institute, Amsterdam (Netherlands); Papanikolaou, Nikos [Laboratory of Computational Medicine, Institute of Computer Science, FORTH, Heraklion, Crete (Greece); Beets-Tan, Regina G.H. [GROW School for Oncology and Developmental Biology, Maastricht University Medical Centre, Maastricht (Netherlands); Department of Radiology, The Netherlands Cancer Institute, Amsterdam (Netherlands)

    2016-03-15

    Purpose: Diffusion-weighted imaging (DWI) tumor volumetry is promising for rectal cancer response assessment, but an important drawback is that manual per-slice tumor delineation can be highly time consuming. This study investigated whether manual DWI-volumetry can be reproduced using a (semi)automated segmentation approach. Methods and Materials: Seventy-nine patients underwent magnetic resonance imaging (MRI) that included DWI (highest b value [b1000 or b1100]) before and after chemoradiation therapy (CRT). Tumor volumes were assessed on b1000 (or b1100) DWI before and after CRT by means of (1) automated segmentation (by 2 inexperienced readers), (2) semiautomated segmentation (manual adjustment of the volumes obtained by method 1 by 2 radiologists), and (3) manual segmentation (by 2 radiologists); this last assessment served as the reference standard. Intraclass correlation coefficients (ICC) and Dice similarity indices (DSI) were calculated to evaluate agreement between different methods and observers. Measurement times (from a radiologist's perspective) were recorded for each method. Results: Tumor volumes were not significantly different among the 3 methods, either before or after CRT (P=.08 to .92). ICCs compared to manual segmentation were 0.80 to 0.91 and 0.53 to 0.66 before and after CRT, respectively, for the automated segmentation and 0.91 to 0.97 and 0.61 to 0.75, respectively, for the semiautomated method. Interobserver agreement (ICC) pre and post CRT was 0.82 and 0.59 for automated segmentation, 0.91 and 0.73 for semiautomated segmentation, and 0.91 and 0.75 for manual segmentation, respectively. Mean DSI between the automated and semiautomated method were 0.83 and 0.58 pre-CRT and post-CRT, respectively; DSI between the automated and manual segmentation were 0.68 and 0.42 and 0.70 and 0.41 between the semiautomated and manual segmentation, respectively. Median measurement time for the radiologists was 0 seconds (pre- and post-CRT) for the

  4. Automated and Semiautomated Segmentation of Rectal Tumor Volumes on Diffusion-Weighted MRI: Can It Replace Manual Volumetry?

    Science.gov (United States)

    van Heeswijk, Miriam M; Lambregts, Doenja M J; van Griethuysen, Joost J M; Oei, Stanley; Rao, Sheng-Xiang; de Graaff, Carla A M; Vliegen, Roy F A; Beets, Geerard L; Papanikolaou, Nikos; Beets-Tan, Regina G H

    2016-03-15

    Diffusion-weighted imaging (DWI) tumor volumetry is promising for rectal cancer response assessment, but an important drawback is that manual per-slice tumor delineation can be highly time consuming. This study investigated whether manual DWI-volumetry can be reproduced using a (semi)automated segmentation approach. Seventy-nine patients underwent magnetic resonance imaging (MRI) that included DWI (highest b value [b1000 or b1100]) before and after chemoradiation therapy (CRT). Tumor volumes were assessed on b1000 (or b1100) DWI before and after CRT by means of (1) automated segmentation (by 2 inexperienced readers), (2) semiautomated segmentation (manual adjustment of the volumes obtained by method 1 by 2 radiologists), and (3) manual segmentation (by 2 radiologists); this last assessment served as the reference standard. Intraclass correlation coefficients (ICC) and Dice similarity indices (DSI) were calculated to evaluate agreement between different methods and observers. Measurement times (from a radiologist's perspective) were recorded for each method. Tumor volumes were not significantly different among the 3 methods, either before or after CRT (P=.08 to .92). ICCs compared to manual segmentation were 0.80 to 0.91 and 0.53 to 0.66 before and after CRT, respectively, for the automated segmentation and 0.91 to 0.97 and 0.61 to 0.75, respectively, for the semiautomated method. Interobserver agreement (ICC) pre and post CRT was 0.82 and 0.59 for automated segmentation, 0.91 and 0.73 for semiautomated segmentation, and 0.91 and 0.75 for manual segmentation, respectively. Mean DSI between the automated and semiautomated method were 0.83 and 0.58 pre-CRT and post-CRT, respectively; DSI between the automated and manual segmentation were 0.68 and 0.42 and 0.70 and 0.41 between the semiautomated and manual segmentation, respectively. Median measurement time for the radiologists was 0 seconds (pre- and post-CRT) for the automated method, 41 to 69 seconds (pre-CRT) and

  5. Global and regional brain volumes normalization in weight-recovered adolescents with anorexia nervosa: preliminary findings of a longitudinal voxel-based morphometry study

    Directory of Open Access Journals (Sweden)

    Bomba M

    2015-03-01

    Full Text Available Monica Bomba,1,* Anna Riva,1,* Sabrina Morzenti,2 Marco Grimaldi,3 Francesca Neri,1 Renata Nacinovich1 1Child and Adolescent Mental Health Department, San Gerardo Hospital, University of Milano-Bicocca, Monza, Italy; 2Medical Physics Department, San Gerardo Hospital, Monza, Italy; 3Department of Radiology, Humanitas Research Hospital, Milan, Italy *These authors contributed equally to this work Abstract: The recent literature on anorexia nervosa (AN suggests that functional and structural abnormalities of cortico-limbic areas might play a role in the evolution of the disease. We explored global and regional brain volumes in a cross-sectional and follow-up study on adolescents affected by AN. Eleven adolescents with AN underwent a voxel-based morphometry study at time of diagnosis and immediately after weight recovery. Data were compared to volumes carried out in eight healthy, age and sex matched controls. Subjects with AN showed increased cerebrospinal fluid volumes and decreased white and gray matter volumes, when compared to controls. Moreover, significant regional gray matter decrease in insular cortex and cerebellum was found at time of diagnosis. No regional white matter decrease was found between samples and controls. Correlations between psychological evaluation and insular volumes were explored. After weight recovery gray matter volumes normalized while reduced global white matter volumes persisted. Keywords: anorexia nervosa, adolescent, gray matter, insula, voxel-based morphometry study

  6. Distribution of volumes of individual glomeruli in kidneys at autopsy: association with age, nephron number, birth weight and body mass index.

    Science.gov (United States)

    Hoy, W E; Hughson, M D; Zimanyi, M; Samuel, T; Douglas-Denton, R; Holden, L; Mott, S; Bertram, J F

    2010-11-01

    Glomerular hypertrophy occurs in a number of normal and pathological states. Glomerular volume in kidneys at autopsy is usually indirectly derived from estimates of total glomerular mass and nephron number, and provides only a single value per kidney, with no indication of the range of volumes of glomeruli within the kidney of any given subject. We review findings of the distribution of volumes of different glomeruli within subjects without kidney disease, and their correlations with age, nephron number, birth weight and body mass index (BMI). The study describes findings from autopsy kidneys of selected adult white males from the Southeast USA who had unexpected deaths, and who did not have renal scarring or renal disease. Total glomerular (nephron) number and total glomerular volume were estimated using the disector/fractionator combination, and mean glomerular volume (Vglom) was derived. The volumes of 30 individual glomeruli (IGV) in each subject were determined using the disector/Cavalieri method. IGV values were compared by categories of age, nephron number, birth weight and BMI. There was substantial variation in IGV within subjects. Older age, lower nephron number, lower birth weight and gross obesity were associated with higher mean IGV and with greater IGV heterogeneity. High Vglom and high IGVs were associated with more glomerulosclerosis. However, amongst the generally modest numbers of sclerosed glomeruli, the pattern was uniformly of ischemic collapse of the glomerular tuft. There was no detectable focal segmental glomerular tuft injury. In this series of people without overt renal disease, greater age, nephron deficit, lower birth weight and obesity were marked by glomerular enlargement and greater glomerular volume heterogeneity within individuals.

  7. Average weighted receiving time in recursive weighted Koch networks

    Indian Academy of Sciences (India)

    Zhenjiang, 212013, People's Republic of China. ∗ ... The properties of a graph can be expressed via its adjacency matrix aij , whose elements take the ... For example, take the worldwide airport networks, where the number of sched- ..... This research is supported by the Humanistic and Social Science Foundation from the.

  8. Weighted Average Cost of Retail Gas (WACORG) highlights pricing effects in the US gas value chain: Do we need wellhead price-floor regulation to bail out the unconventional gas industry?

    International Nuclear Information System (INIS)

    Weijermars, Ruud

    2011-01-01

    The total annual revenue stream in the US natural gas value chain over the past decade is analyzed. Growth of total revenues has been driven by higher wellhead prices, which peaked in 2008. The emergence of the unconventional gas business was made possible in part by the pre-recessional rise in global energy prices. The general rise in natural gas prices between 1998 and 2008 did not lower overall US gas consumption, but shifts have occurred during the past decade in the consumption levels of individual consumer groups. Industry's gas consumption has decreased, while power stations increased their gas consumption. Commercial and residential consumers maintained flat gas consumption patterns. This study introduces the Weighted Average Cost of Retail Gas (WACORG) as a tool to calculate and monitor an average retail price based on the different natural gas prices charged to the traditional consumer groups. The WACORG also provides insight in wellhead revenues and may be used as an instrument for calibrating retail prices in support of wellhead price-floor regulation. Such price-floor regulation is advocated here as a possible mitigation measure against excessive volatility in US wellhead gas prices to improve the security of gas supply. - Highlights: → This study introduces an average retail price, WACORG. → WACORG can monitor price differentials for the traditional US gas consumer groups. → WACORG also provides insight in US wellhead revenues. → WACORG can calibrate retail prices in support of wellhead price-floor regulation. → Gas price-floor can improve security of gas supply by reducing price volatility.

  9. Accuracy of DXA scanning of the thoracic spine: cadaveric studies comparing BMC, areal BMD and geometric estimates of volumetric BMD against ash weight and CT measures of bone volume.

    Science.gov (United States)

    Sran, Meena M; Khan, Karim M; Keiver, Kathy; Chew, Jason B; McKay, Heather A; Oxland, Thomas R

    2005-12-01

    Biomechanical studies of the thoracic spine often scan cadaveric segments by dual energy X-ray absorptiometry (DXA) to obtain measures of bone mass. Only one study has reported the accuracy of lateral scans of thoracic vertebral bodies. The accuracy of DXA scans of thoracic spine segments and of anterior-posterior (AP) thoracic scans has not been investigated. We have examined the accuracy of AP and lateral thoracic DXA scans by comparison with ash weight, the gold-standard for measuring bone mineral content (BMC). We have also compared three methods of estimating volumetric bone mineral density (vBMD) with a novel standard-ash weight (g)/bone volume (cm3) as measured by computed tomography (CT). Twelve T5-T8 spine segments were scanned with DXA (AP and lateral) and CT. The T6 vertebrae were excised, the posterior elements removed and then the vertebral bodies were ashed in a muffle furnace. We proposed a new method of estimating vBMD and compared it with two previously published methods. BMC values from lateral DXA scans displayed the strongest correlation with ash weight (r=0.99) and were on average 12.8% higher (pBMC (AP or lateral) was more strongly correlated with ash weight than areal bone mineral density (aBMD; AP: r=0.54, or lateral: r=0.71) or estimated vBMD. Estimates of vBMD with either of the three methods were strongly and similarly correlated with volumetric BMD calculated by dividing ash weight by CT-derived volume. These data suggest that readily available DXA scanning is an appropriate surrogate measure for thoracic spine bone mineral and that the lateral scan might be the scan method of choice.

  10. Caltrans Average Annual Daily Traffic Volumes (2004)

    Data.gov (United States)

    California Environmental Health Tracking Program — [ from http://www.ehib.org/cma/topic.jsp?topic_key=79 ] Traffic exhaust pollutants include compounds such as carbon monoxide, nitrogen oxides, particulates (fine...

  11. Anatomical and functional volume concordance between FDG PET, and T2 and diffusion-weighted MRI for cervical cancer: a hybrid PET/MR study

    International Nuclear Information System (INIS)

    Sun, Hongzan; Xin, Jun; Zhang, Shaomin; Guo, Qiyong; Lu, Yueyue; Zhai, Wei; Zhao, Long; Peng, Weiai; Wang, Baijun

    2014-01-01

    To evaluate the concordance among 18 F-FDG PET imaging, MR T2-weighted (T2-W) imaging and apparent diffusion coefficient (ADC) maps with diffusion-weighted (DW) imaging in cervical cancer using hybrid whole-body PET/MR. This study prospectively included 35 patients with cervical cancer who underwent pretreatment 18 F-FDG PET/MR imaging. 18 F-FDG PET and MR images were fused using standard software. The percent of the maximum standardized uptake values (SUV max ) was used to contour tumours on PET images, and volumes were calculated automatically. Tumour volumes measured on T2-W and DW images were calculated with standard techniques of tumour area multiplied by the slice profile. Parametric statistics were used for data analysis. FDG PET tumour volumes calculated using SUV max (14.30 ± 4.70) and T2-W imaging volume (33.81 ± 27.32 cm 3 ) were similar (P > 0.05) at 35 % and 40 % of SUV max (32.91 ± 18.90 cm 3 and 27.56 ± 17.19 cm 3 respectively) and significantly correlated (P 3 . DW volumes were not significantly different from FDG PET volumes at either 35 % SUV max or 40 % SUV max or from T2-W imaging volumes (P > 0.05). PET subvolumes with increasing SUV max cut-off percentage showed an inverse change in mean ADC values on DW imaging (P max is recommended for 18 F-FDG PET/MR SUV-based tumour volume estimation. The linear tumour subvolume concordance between FDG PET and DW imaging demonstrates individual regional concordance of metabolic activity and cell density. (orig.)

  12. Increasing the Accuracy of Volume and ADC Delineation for Heterogeneous Tumor on Diffusion-Weighted MRI: Correlation with PET/CT

    Energy Technology Data Exchange (ETDEWEB)

    Gong, Nan-Jie [Department of Diagnostic Radiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong (China); Wong, Chun-Sing, E-mail: drcswong@gmail.com [Department of Diagnostic Radiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong (China); Chu, Yiu-Ching [Department of Radiology, Kwong Wah Hospital, Hong Kong (China); Guo, Hua [Department of Biomedical Engineering, School of Medicine, Tsinghua University, Beijing (China); Huang, Bingsheng [Department of Diagnostic Radiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong (China); Chan, Queenie [Philips Healthcare, Hong Kong (China)

    2013-10-01

    Purpose: To improve the accuracy of volume and apparent diffusion coefficient (ADC) measurements in diffusion-weighted magnetic resonance imaging (MRI), we proposed a method based on thresholding both the b0 images and the ADC maps. Methods and Materials: In 21 heterogeneous lesions from patients with metastatic gastrointestinal stromal tumors (GIST), gross lesion were manually contoured, and corresponding volumes and ADCs were denoted as gross tumor volume (GTV) and gross ADC (ADC{sub g}), respectively. Using a k-means clustering algorithm, the probable high-cellularity tumor tissues were selected based on b0 images and ADC maps. ADC and volume of the tissues selected using the proposed method were denoted as thresholded ADC (ADC{sub thr}) and high-cellularity tumor volume (HCTV), respectively. The metabolic tumor volume (MTV) in positron emission tomography (PET)/computed tomography (CT) was measured using 40% maximum standard uptake value (SUV{sub max}) as the lower threshold, and corresponding mean SUV (SUV{sub mean}) was also measured. Results: HCTV had excellent concordance with MTV according to Pearson's correlation (r=0.984, P<.001) and linear regression (slope = 1.085, intercept = −4.731). In contrast, GTV overestimated the volume and differed significantly from MTV (P=.005). ADC{sub thr} correlated significantly and strongly with SUV{sub mean} (r=−0.807, P<.001) and SUV{sub max} (r=−0.843, P<.001); both were stronger than those of ADC{sub g}. Conclusions: The proposed lesion-adaptive semiautomatic method can help segment high-cellularity tissues that match hypermetabolic tissues in PET/CT and enables more accurate volume and ADC delineation on diffusion-weighted MR images of GIST.

  13. Weight and body mass index in relation to irradiated volume and to overall survival in patients with oropharyngeal cancer: a retrospective cohort study

    International Nuclear Information System (INIS)

    Ottosson, Sandra; Söderström, Karin; Kjellén, Elisabeth; Nilsson, Per; Zackrisson, Björn; Laurell, Göran

    2014-01-01

    Weight loss is a common problem in patients with Squamous Cell Carcinoma of the Head and Neck (SCCHN) treated with radiotherapy (RT). The aims of the present study were to determine if treated volume (TV), as a measure of the radiation dose burden, can predict weight loss in patients with oropharyngeal cancer and to analyze weight loss and body mass index (BMI) in the same patient group in relation to 5-year overall survival. The ARTSCAN trial is a prospective, randomized, multicenter trial in patients with SCCHN. Nutritional data from the ARTSCAN trial were analyzed retrospectively using univariate and multivariate statistical methods based on information on percentage weight loss from the start of RT up to five months after the termination of RT (study cohort 1, n = 232) and information on patients’ BMI at the start of RT (study cohort 2, n = 203). TV was defined as the volume of the patient receiving at least 95% of the prescribed dose. TV 64.6Gy encompasses macroscopic tumor and TV 43.7Gy elective lymph nodes of the neck. TV 64.6Gy and TV 43.7Gy were both significantly correlated with higher weight loss up to five months after the termination of RT in study cohort 1 (p < 0.001 for both). BMI at the start of RT was shown to be a prognostic factor for 5-year overall survival in study cohort 2 but weight loss was not. The hazard ratios and 95% confidence intervals were 3.78 (1.46–9.75) and 2.57 (1.43–4.62) in patients with underweight and normal weight, respectively. TV can predict weight loss during RT in patients with oropharyngeal cancer regardless of clinical stage. A high BMI (>25 kg/m 2 ) at the start of RT is positively associated with survival in patients with oropharyngeal cancer

  14. Lagrangian averaging with geodesic mean.

    Science.gov (United States)

    Oliver, Marcel

    2017-11-01

    This paper revisits the derivation of the Lagrangian averaged Euler (LAE), or Euler- α equations in the light of an intrinsic definition of the averaged flow map as the geodesic mean on the volume-preserving diffeomorphism group. Under the additional assumption that first-order fluctuations are statistically isotropic and transported by the mean flow as a vector field, averaging of the kinetic energy Lagrangian of an ideal fluid yields the LAE Lagrangian. The derivation presented here assumes a Euclidean spatial domain without boundaries.

  15. Liver volume, intrahepatic fat and body weight in the course of a lifestyle interventional study. Analysis with quantitative MR-based methods; Lebervolumen, Leberfettanteil und Koerpergewicht im Verlauf einer Lebensstilinterventionsstudie. Eine Analyse mit quantitativen MR-basierten Methoden

    Energy Technology Data Exchange (ETDEWEB)

    Bongers, M.N. [Klinikum der Eberhard-Karls-Universitaet Tuebingen, Abteilung fuer Diagnostische und Interventionelle Radiologie, Tuebingen (Germany); Universitaetsklinikum Tuebingen, Sektion fuer Experimentelle Radiologie der Abteilung fuer Diagnostische und Interventionelle Radiologie, Tuebingen (Germany); Stefan, N.; Fritsche, A.; Haering, H.U. [Universitaetsklinikum Tuebingen, Innere Medizin IV - Endokrinologie und Diabetologie, Angiologie, Nephrologie und Klinische Chemie, Tuebingen (Germany); Helmholtz-Zentrum Muenchen an der Universitaet Tuebingen, Institut fuer Diabetes-Forschung und Metabolische Erkrankungen (IDM), Tuebingen (Germany); Nikolaou, K. [Klinikum der Eberhard-Karls-Universitaet Tuebingen, Abteilung fuer Diagnostische und Interventionelle Radiologie, Tuebingen (Germany); Schick, F. [Universitaetsklinikum Tuebingen, Sektion fuer Experimentelle Radiologie der Abteilung fuer Diagnostische und Interventionelle Radiologie, Tuebingen (Germany); Machann, J. [Universitaetsklinikum Tuebingen, Sektion fuer Experimentelle Radiologie der Abteilung fuer Diagnostische und Interventionelle Radiologie, Tuebingen (Germany); Helmholtz-Zentrum Muenchen an der Universitaet Tuebingen, Institut fuer Diabetes-Forschung und Metabolische Erkrankungen (IDM), Tuebingen (Germany); Deutsches Zentrum fuer Diabetesforschung (DZD), Neuherberg (Germany)

    2015-04-01

    The aim of this study was to investigate potential associations between changes in liver volume, the amount of intrahepatic lipids (IHL) and body weight during lifestyle interventions. In a prospective study 150 patients with an increased risk for developing type 2 diabetes mellitus were included who followed a caloric restriction diet for 6 months. In the retrospective analysis 18 women and 9 men (age range 22-71 years) with an average body mass index (BMI) of 32 kg/m{sup 2} were enrolled. The liver volume was determined at the beginning and after 6 months by three-dimensional magnetic resonance imaging (3D-MRI, echo gradient, opposed-phase) and IHLs were quantified by volume-selective MR spectroscopy in single voxel stimulated echo acquisition mode (STEAM). Univariable and multivariable correlation analyses between changes of liver volume (Δliver volume), intrahepatic lipids (ΔIHL) and body weight (ΔBW) were performed. Univariable correlation analysis in the whole study cohort showed associations between ΔIHL and ΔBW (r = 0.69; p < 0.0001), ΔIHL and Δliver volume (r = 0.66; p = 0.0002) as well as ΔBW and Δliver volume (r = 0.5; p = 0.0073). Multivariable correlation analysis revealed that changes of liver volume are primarily determined by changes in IHL independent of changes in body weight (β = 0.0272; 95 % CI: 0.0155-0.034; p < 0.0001). Changes of liver volume during lifestyle interventions are independent of changes of body weight primarily determined by changes of IHL. These results show the reversibility of augmented liver volume in steatosis if it is possible to reduce IHLs during lifestyle interventions. (orig.) [German] Lassen sich Zusammenhaenge zwischen den Aenderungen des Lebervolumens, des Anteils intrahepatischer Lipide und des Koerpergewichts waehrend einer Lebensstilintervention feststellen ?In einer prospektiven Interventionsstudie unterzogen sich 150 Probanden mit erhoehtem Diabetesrisiko fuer 6 Monate einer diaetetischen

  16. Application of volume-weighted skew-upwind differencing to thermal and fluid mixing in the cold leg and downcomer of a PWR

    International Nuclear Information System (INIS)

    Chen, F.F.; Miao, C.C.; Chen, B.C.J.; Domanus, H.M.; Lyczkowski, R.W.; Sha, W.T.

    1983-01-01

    Upwind differencing has been the most common numerical scheme used in computational fluid flow and heat transfer in past years. However, the numerical diffusion induced by the use of upwind differencing can be significant in problems involving thermal mixing. Thermal and fluid mixing in a pressurized water reactor during high pressurized coolant injection is a typical example where numerical diffusion is significant. An improved volume-weighted skew-upwind differencing is used here to reduce numerical diffusion without overshooting or undershooting which is the major defect of original skew-upwind differencing proposed by Raithby. The basic concept of volume-weighted skew-upwind differencing is shown. Computations were performed using COMMIX-1B, an extended version of the COMMIX-1A. The experiment analyzed here is test No. 1 of the SAI experiment

  17. Seasonal variations in the volume of the haemolymph and body weight of the horseshoe crab, Tachypleus gigas (Muller)

    Digital Repository Service at National Institute of Oceanography (India)

    Chatterji, A.; Rathod, V.; Parulekar, A.H.

    in sizes between 121-140 mm. An inverse relationship was observed between the volume of haemolymph and salinity of the environment. Maximum volume of haemolymph (57.3 ml) in females was observed when the salinity of the environment was low in October...

  18. Anatomical and functional volume concordance between FDG PET, and T2 and diffusion-weighted MRI for cervical cancer: a hybrid PET/MR study

    Energy Technology Data Exchange (ETDEWEB)

    Sun, Hongzan; Xin, Jun; Zhang, Shaomin; Guo, Qiyong; Lu, Yueyue; Zhai, Wei; Zhao, Long [Shengjing Hospital of China Medical University, Department of Radiology, Shenyang, Liaoning (China); Peng, Weiai [NM Marketing, Great China, Philips Healthcare, Guangzhou (China); Wang, Baijun [Philips China Investment Co. Ltd. Shenyang Office, Shenyang, Liaoning (China)

    2014-05-15

    To evaluate the concordance among {sup 18}F-FDG PET imaging, MR T2-weighted (T2-W) imaging and apparent diffusion coefficient (ADC) maps with diffusion-weighted (DW) imaging in cervical cancer using hybrid whole-body PET/MR. This study prospectively included 35 patients with cervical cancer who underwent pretreatment {sup 18}F-FDG PET/MR imaging. {sup 18}F-FDG PET and MR images were fused using standard software. The percent of the maximum standardized uptake values (SUV{sub max}) was used to contour tumours on PET images, and volumes were calculated automatically. Tumour volumes measured on T2-W and DW images were calculated with standard techniques of tumour area multiplied by the slice profile. Parametric statistics were used for data analysis. FDG PET tumour volumes calculated using SUV{sub max} (14.30 ± 4.70) and T2-W imaging volume (33.81 ± 27.32 cm{sup 3}) were similar (P > 0.05) at 35 % and 40 % of SUV{sub max} (32.91 ± 18.90 cm{sup 3} and 27.56 ± 17.19 cm{sup 3} respectively) and significantly correlated (P < 0.001; r = 0.735 and 0.766). The mean DW volume was 30.48 ± 22.41 cm{sup 3}. DW volumes were not significantly different from FDG PET volumes at either 35 % SUV{sub max} or 40 % SUV{sub max} or from T2-W imaging volumes (P > 0.05). PET subvolumes with increasing SUV{sub max} cut-off percentage showed an inverse change in mean ADC values on DW imaging (P < 0.001, ANOVA). Hybrid PET/MR showed strong volume concordance between FDG PET, and T2-W and DW imaging in cervical cancer. Cut-off at 35 % or 40 % of SUV{sub max} is recommended for {sup 18}F-FDG PET/MR SUV-based tumour volume estimation. The linear tumour subvolume concordance between FDG PET and DW imaging demonstrates individual regional concordance of metabolic activity and cell density. (orig.)

  19. Batch medication of intestinal infections in nursery pigs-A randomised clinical trial on the efficacy of treatment strategy, type of antibiotic and bacterial load on average daily weight gain.

    Science.gov (United States)

    Weber, Nicolai Rosager; Pedersen, Ken Steen; Hansen, Christian Fink; Denwood, Matthew; Hjulsager, Charlotte Kristiane; Nielsen, Jens Peter

    2017-02-01

    Previous research projects have demonstrated the need for better diagnostic tools to support decisions on medication strategies for infections caused by Escherichia coli F4 (F4) and F18 (F18), Lawsonia intracellularis (LI) and Brachyspira pilosicoli (PILO). This study was carried out as a randomised clinical trial in three Danish pig herds and included 1047 nursery pigs, distributed over 10 batches and 78 pens. The objectives of this study were: (1) to assess the effect of four 5-day treatment strategies (initiated at clinical outbreak of diarrhoea or at fixed time points 14, 21, or 28days after weaning) on average daily weight gain (ADG); (2) to compare the effect of treatment with doxycycline or tylosine on diarrhoea prevalence, pathogenic bacterial load, and ADG; (3) to evaluate PCR testing of faecal pen floor samples as a diagnostic tool for determining the optimal time of treatment. (1) The four treatment strategies had a significant overall effect on ADG (p=0.01). Pigs starting treatment 14days after weaning had a significantly higher ADG (42 g) compared to pigs treated on day 28 (p=0.01). (2) When measured 2days after treatment, doxycycline treatment resulted in fewer LI-positive pens (p=0.004), lower excretion levels of LI (p=0.013), and fewer pens with a high level of LI (p=0.031) compared to pens treated with tylosine. There was no significant difference in F4, F18 and PILO levels after treatment with the two antibiotic compounds. There was a significant difference (p=0.04) of mean diarrhoea prevalence on day 21 of the study between pens treated with tylosine (0.254, 95% CI: 0.184-0.324), and doxycycline (0.167, 95% CI: 0.124-0.210). The type of antibiotic compound was not found to have a significant effect on ADG (p=0.209). (3) Pigs starting treatment on day 14 in pens where F4, F18, LI or PILO were detected by qPCR on the pen floor had a statistically significant increase in ADG (66g) compared to pigs treated on day 14 in pens where no enteric pathogens

  20. Volume de iogurte light e sensações subjetivas do apetite de homens eutróficos e com excesso de peso Volume of light yogurt and subjective appetite sensations in normal-weight and overweight men

    Directory of Open Access Journals (Sweden)

    Luciana Neri Nobre

    2006-10-01

    Full Text Available OBJETIVO: Avaliar, independentemente de outras variáveis, o efeito do volume de iogurte light sobre os parâmetros de ingestão alimentar de homens saudáveis. MÉTODOS: Foi feita incorporação de ar ao iogurte por adição de um produto comercialmente disponível -Emustab® - (6g/300ml com posterior homogeneização em liqüidificador semi-industrial. Utilizaram-se três volumes de iogurte: 300, 450 e 600ml. Trabalhou-se com 20 participantes saudáveis, sendo 10 eutróficos, com índice de massa corporal entre 19 e 24,9kg/m² e 10 com excesso de peso, índice de massa corporal >25kg/m². Cada um deles recebeu um volume de iogurte em três diferentes dias, pela manhã, em jejum de 12 horas. Uma escala de analogia visual foi utilizada, num período de 4 horas e 30 minutos após ingestão de cada volume do iogurte, para avaliar sensações subjetivas de saciedade, fome e desejo por alimentos específicos. RESULTADOS: Os volumes do iogurte light afetaram a saciedade dos dois grupos estudados, sendo que o maior volume exerceu melhor essa ação (pOBJECTIVE: This study aimed to evaluate the effect of light yogurt volume on the food intake of healthy men regardless of other variables. METHODS: Air was added to the yogurt by mixing it with a commercially available product, Emustab®, (6g/300ml and homogenized in a semi-industrial blender. Three volumes of yogurt were used: 300, 450 and 600ml. Twenty healthy volunteers participated in the study, 10 with normal weight, Body Mass Index from 19 to 24.9kg/m² and 10 with excess weight, Body Mass Index >25kg/m². Each one of them was given a yogurt volume in three different days in the morning, after a 12 hour fast. After the intake of each yogurt volume, a visual analog scale was used to assess the subjective sensations of satiety, hunger and desire for specific foods. RESULTS: Light yogurt volumes affected the satiety of both studied groups and the greater volume was more effective (p<0.01. The highest

  1. Measurement of brain perfusion, blood volume, and blood-brain barrier permeability, using dynamic contrast-enhanced T(1)-weighted MRI at 3 tesla

    DEFF Research Database (Denmark)

    Larsson, Henrik B W; Courivaud, Frédéric; Rostrup, Egill

    2009-01-01

    Assessment of vascular properties is essential to diagnosis and follow-up and basic understanding of pathogenesis in brain tumors. In this study, a procedure is presented that allows concurrent estimation of cerebral perfusion, blood volume, and blood-brain permeability from dynamic T(1)-weighted...... on a pixel-by-pixel basis of cerebral perfusion, cerebral blood volume, and blood-brain barrier permeability.......Assessment of vascular properties is essential to diagnosis and follow-up and basic understanding of pathogenesis in brain tumors. In this study, a procedure is presented that allows concurrent estimation of cerebral perfusion, blood volume, and blood-brain permeability from dynamic T(1)-weighted...... imaging of a bolus of a paramagnetic contrast agent passing through the brain. The methods are applied in patients with brain tumors and in healthy subjects. Perfusion was estimated by model-free deconvolution using Tikhonov's method (gray matter/white matter/tumor: 72 +/- 16/30 +/- 8/56 +/- 45 mL/100 g...

  2. How to average logarithmic retrievals?

    Directory of Open Access Journals (Sweden)

    B. Funke

    2012-04-01

    Full Text Available Calculation of mean trace gas contributions from profiles obtained by retrievals of the logarithm of the abundance rather than retrievals of the abundance itself are prone to biases. By means of a system simulator, biases of linear versus logarithmic averaging were evaluated for both maximum likelihood and maximum a priori retrievals, for various signal to noise ratios and atmospheric variabilities. These biases can easily reach ten percent or more. As a rule of thumb we found for maximum likelihood retrievals that linear averaging better represents the true mean value in cases of large local natural variability and high signal to noise ratios, while for small local natural variability logarithmic averaging often is superior. In the case of maximum a posteriori retrievals, the mean is dominated by the a priori information used in the retrievals and the method of averaging is of minor concern. For larger natural variabilities, the appropriateness of the one or the other method of averaging depends on the particular case because the various biasing mechanisms partly compensate in an unpredictable manner. This complication arises mainly because of the fact that in logarithmic retrievals the weight of the prior information depends on abundance of the gas itself. No simple rule was found on which kind of averaging is superior, and instead of suggesting simple recipes we cannot do much more than to create awareness of the traps related with averaging of mixing ratios obtained from logarithmic retrievals.

  3. Neutron resonance averaging

    International Nuclear Information System (INIS)

    Chrien, R.E.

    1986-10-01

    The principles of resonance averaging as applied to neutron capture reactions are described. Several illustrations of resonance averaging to problems of nuclear structure and the distribution of radiative strength in nuclei are provided. 30 refs., 12 figs

  4. Light-Weight Radioisotope Heater Unit Safety Analysis Report (LWRHU-SAR). Volume II. Accident model document

    International Nuclear Information System (INIS)

    Johnson, E.W.

    1985-10-01

    Purposes of this volume (AMD), are to: Identify all malfunctions, both singular and multiple, which can occur during the complete mission profile that could lead to release outside the clad of the radioisotopic material contained therein; provide estimates of occurrence probabilities associated with these various accidents; evaluate the response of the LWRHU (or its components) to the resultant accident environments; and associate the potential event history with test data or analysis to determine the potential interaction of the released radionuclides with the biosphere

  5. Small volume transfusion of irradiated red blood cells using satellite bags in very low birth weight infants

    International Nuclear Information System (INIS)

    Yamagiwa, Kazuhiro; Honda, Yoshinobu; Sakuma, Kimiko; Igarashi, Etsuo; Watanabe, Masahiko; Ujiie, Niro; Suzuki, Hitoshi; Ohto, Hitoshi

    1993-01-01

    We have treated anemia of prematurity with concentrated red cells divided into 3 packs by using the Sterile Connection Device (SCD, USA). This study was performed to reveal the influence for very low birth weight infants of transfusion of red cells stored after irradiation. The following facts were observed in infants after transfusion: (1) no change in sodium and potassium level and leucocyte count, (2) increased amount of total bilirubin but no change in unbound bilirubin level, (3) decrease in platelet count less than 50,000/mm 3 . According to these results we conclude that the transfusion of concentrated red blood cells stored within 2 weeks after irradiation was safe even for very low birth weight infants. (author)

  6. Averaging in spherically symmetric cosmology

    International Nuclear Information System (INIS)

    Coley, A. A.; Pelavas, N.

    2007-01-01

    The averaging problem in cosmology is of fundamental importance. When applied to study cosmological evolution, the theory of macroscopic gravity (MG) can be regarded as a long-distance modification of general relativity. In the MG approach to the averaging problem in cosmology, the Einstein field equations on cosmological scales are modified by appropriate gravitational correlation terms. We study the averaging problem within the class of spherically symmetric cosmological models. That is, we shall take the microscopic equations and effect the averaging procedure to determine the precise form of the correlation tensor in this case. In particular, by working in volume-preserving coordinates, we calculate the form of the correlation tensor under some reasonable assumptions on the form for the inhomogeneous gravitational field and matter distribution. We find that the correlation tensor in a Friedmann-Lemaitre-Robertson-Walker (FLRW) background must be of the form of a spatial curvature. Inhomogeneities and spatial averaging, through this spatial curvature correction term, can have a very significant dynamical effect on the dynamics of the Universe and cosmological observations; in particular, we discuss whether spatial averaging might lead to a more conservative explanation of the observed acceleration of the Universe (without the introduction of exotic dark matter fields). We also find that the correlation tensor for a non-FLRW background can be interpreted as the sum of a spatial curvature and an anisotropic fluid. This may lead to interesting effects of averaging on astrophysical scales. We also discuss the results of averaging an inhomogeneous Lemaitre-Tolman-Bondi solution as well as calculations of linear perturbations (that is, the backreaction) in an FLRW background, which support the main conclusions of the analysis

  7. Volume and weight characteristics of a typical Douglas-fir/ western larch stand, Coram Experimental Forest, Montana

    Science.gov (United States)

    Robert E. Benson; Joyce A. Schlieter

    1980-01-01

    An over-mature Douglas-fir/western larch stand on the Coram Experimental Forest in Montana averaged about 7,300 ft3/acre (511 rn3/ha) of wood over 3 inches (7.62 cm) in diameter, and an additional 57 tons/acre (128/ha) of fine material, before harvest. After logging, using three different cutting methods and four different levels of utilization, wood residues ranged...

  8. Molecular weight (hydrodynamic volume) dictates the systemic pharmacokinetics and tumour disposition of PolyPEG star polymers.

    Science.gov (United States)

    Khor, Song Yang; Hu, Jinming; McLeod, Victoria M; Quinn, John F; Williamson, Mark; Porter, Christopher J H; Whittaker, Michael R; Kaminskas, Lisa M; Davis, Thomas P

    2015-11-01

    Herein we report for the first time the biological fate of poly[(oligoethylene glycol) acrylate] (POEGA) star polymers synthesised via a versatile arm-first reversible addition-fragmentation chain transfer (RAFT) polymerisation approach. The biopharmaceutical behaviour of three different molecular weight (49, 64 and 94kDa) POEGA stars was evaluated in rats and nude mice bearing human MDA MB-231 tumours after intravenous administration. The 94kDa star polymer exhibited a longer plasma exposure time than the 49kDa or 64kDa star polymer; an observation attributable to differences in the rates of both polymer biodegradation and urinary excretion. Tumour biodistribution also correlated with molecular weight and was greatest for the longest circulating 94kDa star. Different patterns of liver and spleen biodistribution were observed between mice and rats for the different sized polymers. The polymers were also well-tolerated in vivo and in vitro at therapeutic concentrations. Advances in nanotechnology has enabled scientists to produce nanoparticle as drug carriers in cancer therapeutics. In this article, the authors studied the biological fate of poly[(oligoethylene glycol) acrylate] (POEGA) star polymers of different size, after intravenous injections. This would allow the subsequent comparison to other drug delivery systems for better drug delivery. Copyright © 2015 Elsevier Inc. All rights reserved.

  9. When good = better than average

    Directory of Open Access Journals (Sweden)

    Don A. Moore

    2007-10-01

    Full Text Available People report themselves to be above average on simple tasks and below average on difficult tasks. This paper proposes an explanation for this effect that is simpler than prior explanations. The new explanation is that people conflate relative with absolute evaluation, especially on subjective measures. The paper then presents a series of four studies that test this conflation explanation. These tests distinguish conflation from other explanations, such as differential weighting and selecting the wrong referent. The results suggest that conflation occurs at the response stage during which people attempt to disambiguate subjective response scales in order to choose an answer. This is because conflation has little effect on objective measures, which would be equally affected if the conflation occurred at encoding.

  10. The correlation between birth weight and insulin-like growth factor-binding protein-1 (IGFBP-1), kisspeptin-1 (KISS-1), and three-dimensional fetal volume.

    Science.gov (United States)

    Kimyon Comert, Gunsu; Esin, Sertac; Caglar, Gamze Sinem; Yirci, Bulent; Ozdemir, Sedat; Demirtas, Selda; Kandemir, Omer

    2018-01-24

    This study aimed to determine the relationship between birth weight, and maternal serum insulin-like growth factor-binding protein-1 (IGFBP-1) and kisspeptin-1 (KISS-1) levels, and first-trimester fetal volume (FV) based on three-dimensional ultrasonography. The study included 142 pregnant women at gestational week 11°-13 6 . All fetuses were imaged ultrasonographically by the same physician. Maternal blood samples were collected at the time of ultrasonographic evaluation and analyzed for IGFBP-1 and KISS-1 levels via enzyme-linked immunosorbent assay (ELISA). Maternal and neonatal weights were recorded at birth. Birth weight ≤10th and the >90th percentiles was defined as small and large for gestational age (SGA and LGA), respectively. Median crown-rump length (CRL), FV, and maternal serum IGFBP-1 and KISS-1 levels were 58.2 mm (35.3-79.2 mm), 16.3 cm 3 (3.8-34.4 cm 3 ), 68.1 ng mL -1 (3.8-377.9 mL -1 ), and 99.7 ng L -1 (42.1-965.3 ng L -1 ), respectively. First-trimester IGFBP-1 levels were significantly lower in the mothers with LGA neonates (p KISS-1 levels. IGFBP-1 levels and maternal weight at delivery were negatively correlated with neonatal birth weight. There was no correlation between CRL or FV and maternal IGFBP-1 or KISS1 levels (p > .05). The maternal IGFBP-1 level during the first trimester was a significant independent factor for SGA and LGA neonates (Odds ratio (OR): 0.011, 95%CI: 1.005-1.018, p KISS-1 level. As compared to the maternal KISS-1 level, the maternal IGFBP-1 level during the first trimester might be a better biomarker of fetal growth. Additional larger scale studies are needed to further delineate the utility of IGFBP-1 as a marker of abnormal birth weight.

  11. Redefining the target early during treatment. Can we visualize regional differences within the target volume using sequential diffusion weighted MRI?

    International Nuclear Information System (INIS)

    Lambrecht, Maarten; Van Herck, Hans; De Keyzer, Frederik; Vandecaveye, Vincent; Slagmolen, Pieter; Suetens, Paul; Hermans, Robert; Nuyts, Sandra

    2014-01-01

    Purpose: In head and neck cancer, diffusion weighted MRI (DWI) can predict response early during treatment. Treatment-induced changes and DWI-specific artifacts hinder an accurate registration between apparent diffusion coefficient (ADC) maps. The aim of the study was to develop a registration tool which calculates and visualizes regional changes in ADC. Methods: Twenty patients with stage IV HNC treated with primary radiotherapy received an MRI including DWI before and early during treatment. Markers were manually placed at anatomical landmarks on the different modalities at both time points. A registration method, consisting of a fully automatic rigid and nonrigid registration and two semi-automatic thin-plate spline (TPS) warps was developed and applied to the image sets. After each registration step the mean registration errors were calculated and ΔADC was compared between good and poor responders. Results: Adding the TPS warps significantly reduced the registration error (in mm, 6.3 ± 6.2 vs 3.2 ± 3.3 mm, p < 0.001). After the marker based registration the median ΔADC in poor responders was significantly lower than in good responders (7% vs. 21%; p < 0.001). Conclusions: This registration method allowed for a significant reduction of the mean registration error. Furthermore the voxel-wise calculation of the ΔADC early during radiotherapy allowed for a visualization of the regional differences of ΔADC within the tumor

  12. On Averaging Rotations

    DEFF Research Database (Denmark)

    Gramkow, Claus

    1999-01-01

    In this article two common approaches to averaging rotations are compared to a more advanced approach based on a Riemannian metric. Very offten the barycenter of the quaternions or matrices that represent the rotations are used as an estimate of the mean. These methods neglect that rotations belo...... approximations to the Riemannian metric, and that the subsequent corrections are inherient in the least squares estimation. Keywords: averaging rotations, Riemannian metric, matrix, quaternion......In this article two common approaches to averaging rotations are compared to a more advanced approach based on a Riemannian metric. Very offten the barycenter of the quaternions or matrices that represent the rotations are used as an estimate of the mean. These methods neglect that rotations belong...

  13. Determination of average molecular weights on organic reactor coolants. I.- Freezing-point depression method for benzene solutions; Determinaciond e masas moleculares medias en refrigerantes nucleares organicos. I.- Crioscopia de disolucion bencenicas

    Energy Technology Data Exchange (ETDEWEB)

    Carreira, M

    1965-07-01

    As a working method for determination of changes in molecular mass that may occur by irradiation (pyrolytic-radiolytic decomposition) of polyphenyl reactor coolants, a cryoscopic technique has been developed which associated the basic simplicity of Beckman's method with some experimental refinements taken out of the equilibrium methods. A total of 18 runs were made on samples of napthalene, biphenyl, and the commercial mixtures OM-2 (Progil) and Santowax-R (Monsanto), with an average deviation from the theoretical molecular mass of 0.6%. (Author) 7 refs.

  14. Determination of average molecular weights on organic reactor coolants. I.- Freezing-point depression method for benzene solutions; Determinaciond e masas moleculares medias en refrigerantes nucleares organicos. I.- Crioscopia de disolucion bencenicas

    Energy Technology Data Exchange (ETDEWEB)

    Carreira, M.

    1965-07-01

    As a working method for determination of changes in molecular mass that may occur by irradiation (pyrolytic-radiolytic decomposition) of polyphenyl reactor coolants, a cryoscopic technique has been developed which associated the basic simplicity of Beckman's method with some experimental refinements taken out of the equilibrium methods. A total of 18 runs were made on samples of napthalene, biphenyl, and the commercial mixtures OM-2 (Progil) and Santowax-R (Monsanto), with an average deviation from the theoretical molecular mass of 0.6%. (Author) 7 refs.

  15. Effects of a Birth Hospital's Neonatal Intensive Care Unit Level and Annual Volume of Very Low-Birth-Weight Infant Deliveries on Morbidity and Mortality.

    Science.gov (United States)

    Jensen, Erik A; Lorch, Scott A

    2015-08-01

    The annual volume of deliveries of very low-birth-weight (VLBW) infants has a greater effect on mortality risk than does neonatal intensive care unit (NICU) level. The differential effect of these hospital factors on morbidity among VLBW infants is uncertain. To assess the independent effects of a birth hospital's annual volume of VLBW infant deliveries and NICU level on the risk of several neonatal morbidities and morbidity-mortality composite outcomes that are predictive of future neurocognitive development. Retrospective, population-based cohort study (performed in 2014) of all VLBW infants without severe congenital anomalies delivered in all hospitals in California, Missouri, and Pennsylvania between January 1, 1999, and December 31, 2009 (N = 72,431). Risk-adjusted odds ratios and risk-adjusted probabilities were determined by logistic regression. The primary study outcomes were the individual composites of death or bronchopulmonary dysplasia, necrotizing enterocolitis, retinopathy of prematurity, and severe intraventricular hemorrhage. Among the 72,431 VLBW infants in the present study, birth at a hospital with 10 or less deliveries of VLBW infants per year was associated with the highest risk-adjusted probability of death (15.3% [95% CI, 14.4%-16.3%]), death or severe intraventricular hemorrhage (17.5% [95% CI, 16.5%-18.6%]), and death or necrotizing enterocolitis (19.3% [95% CI, 18.1%-20.4%]). These complications were also more common among infants born at hospitals with a level I or II NICU compared with infants delivered at hospitals with a level IIIB/C NICU. The risk-adjusted probability of death or retinopathy of prematurity was highest among infants born at hospitals with a level IIIB/C NICU and lowest among infants born at hospitals with a level IIIA NICU. When the effects of NICU level and annual volume of VLBW infant deliveries were evaluated simultaneously, the annual volume of deliveries was the stronger contributor to the risk of death, death or

  16. Monitoring early response to anti-angiogenic therapy: diffusion-weighted magnetic resonance imaging and volume measurements in colon carcinoma xenografts.

    Directory of Open Access Journals (Sweden)

    Moritz Jörg Schneider

    Full Text Available OBJECTIVES: To evaluate the use of diffusion-weighted MRI (DW-MRI and volume measurements for early monitoring of antiangiogenic therapy in an experimental tumor model. MATERIALS AND METHODS: 23 athymic nude rats, bearing human colon carcinoma xenografts (HT-29 were examined before and after 6 days of treatment with regorafenib (n = 12 or placebo (n = 11 in a clinical 3-Tesla MRI. For DW-MRI, a single-shot EPI sequence with 9 b-values (10-800 s/mm2 was used. The apparent diffusion coefficient (ADC was calculated voxelwise and its median value over a region of interest, covering the entire tumor, was defined as the tumor ADC. Tumor volume was determined using T2-weighted images. ADC and volume changes between first and second measurement were evaluated as classifiers by a receiver-operator-characteristic (ROC analysis individually and combined using Fisher's linear discriminant analysis (FLDA. RESULTS: All ADCs and volumes are stated as median±standard deviation. Tumor ADC increased significantly in the therapy group (0.76±0.09×10(-3 mm2/s to 0.90±0.12×10(-3 mm2/s; p<0.001, with significantly higher changes of tumor ADC than in the control group (0.10±0.11×10(-3 mm2/s vs. 0.03±0.09×10(-3 mm2/s; p = 0.027. Tumor volume increased significantly in both groups (therapy: 347.8±449.1 to 405.3±823.6 mm3; p = 0.034; control: 219.7±79.5 to 443.7±141.5 mm3; p<0.001, however, the therapy group showed significantly reduced tumor growth (33.30±47.30% vs. 96.43±31.66%; p<0.001. Area under the curve and accuracy of the ADC-based ROC analysis were 0.773 and 78.3%; and for the volume change 0.886 and 82.6%. The FLDA approach yielded an AUC of 0.985 and an accuracy of 95.7%. CONCLUSIONS: Regorafenib therapy significantly increased tumor ADC after 6 days of treatment and also significantly reduced tumor growth. However, ROC analyses using each parameter individually revealed a lack of accuracy in discriminating between therapy and

  17. Averaged RMHD equations

    International Nuclear Information System (INIS)

    Ichiguchi, Katsuji

    1998-01-01

    A new reduced set of resistive MHD equations is derived by averaging the full MHD equations on specified flux coordinates, which is consistent with 3D equilibria. It is confirmed that the total energy is conserved and the linearized equations for ideal modes are self-adjoint. (author)

  18. Determining average yarding distance.

    Science.gov (United States)

    Roger H. Twito; Charles N. Mann

    1979-01-01

    Emphasis on environmental and esthetic quality in timber harvesting has brought about increased use of complex boundaries of cutting units and a consequent need for a rapid and accurate method of determining the average yarding distance and area of these units. These values, needed for evaluation of road and landing locations in planning timber harvests, are easily and...

  19. Average Revisited in Context

    Science.gov (United States)

    Watson, Jane; Chick, Helen

    2012-01-01

    This paper analyses the responses of 247 middle school students to items requiring the concept of average in three different contexts: a city's weather reported in maximum daily temperature, the number of children in a family, and the price of houses. The mixed but overall disappointing performance on the six items in the three contexts indicates…

  20. Averaging operations on matrices

    Indian Academy of Sciences (India)

    2014-07-03

    Jul 3, 2014 ... Role of Positive Definite Matrices. • Diffusion Tensor Imaging: 3 × 3 pd matrices model water flow at each voxel of brain scan. • Elasticity: 6 × 6 pd matrices model stress tensors. • Machine Learning: n × n pd matrices occur as kernel matrices. Tanvi Jain. Averaging operations on matrices ...

  1. Average-energy games

    Directory of Open Access Journals (Sweden)

    Patricia Bouyer

    2015-09-01

    Full Text Available Two-player quantitative zero-sum games provide a natural framework to synthesize controllers with performance guarantees for reactive systems within an uncontrollable environment. Classical settings include mean-payoff games, where the objective is to optimize the long-run average gain per action, and energy games, where the system has to avoid running out of energy. We study average-energy games, where the goal is to optimize the long-run average of the accumulated energy. We show that this objective arises naturally in several applications, and that it yields interesting connections with previous concepts in the literature. We prove that deciding the winner in such games is in NP inter coNP and at least as hard as solving mean-payoff games, and we establish that memoryless strategies suffice to win. We also consider the case where the system has to minimize the average-energy while maintaining the accumulated energy within predefined bounds at all times: this corresponds to operating with a finite-capacity storage for energy. We give results for one-player and two-player games, and establish complexity bounds and memory requirements.

  2. General considerations of the choice of dose limits, averaging areas and weighting factors for the skin in the light of revised skin cancer risk figures and experimental data on non-stochastic effects

    International Nuclear Information System (INIS)

    Charles, M.W.

    1990-01-01

    Recent biological data from man and pig on the non-stochastic effects following exposure with a range of β-emitters are combined with recent epidemiological analyses of skin cancer risks in man to form a basis for suggested improved protection criteria following whole- or partial-body skin exposures. Specific consideration is given to the choice of an organ weighting factor for evaluation of effective dose-equivalent. Since stochastic and non-stochastic end-points involve different cell types at different depths in the skin, the design of an ideal physical dosemeter may depend on the proportion of the body skin exposed and the radiation penetrating power. Possible choices of design parameters for skin dosemeters are discussed. Limitation of skin exposure from small radioactive sources ('hot particles') is addressed using animal data. (author)

  3. Assessment of treatment response by total tumor volume and global apparent diffusion coefficient using diffusion-weighted MRI in patients with metastatic bone disease: a feasibility study.

    Directory of Open Access Journals (Sweden)

    Matthew D Blackledge

    Full Text Available We describe our semi-automatic segmentation of whole-body diffusion-weighted MRI (WBDWI using a Markov random field (MRF model to derive tumor total diffusion volume (tDV and associated global apparent diffusion coefficient (gADC; and demonstrate the feasibility of using these indices for assessing tumor burden and response to treatment in patients with bone metastases. WBDWI was performed on eleven patients diagnosed with bone metastases from breast and prostate cancers before and after anti-cancer therapies. Semi-automatic segmentation incorporating a MRF model was performed in all patients below the C4 vertebra by an experienced radiologist with over eight years of clinical experience in body DWI. Changes in tDV and gADC distributions were compared with overall response determined by all imaging, tumor markers and clinical findings at serial follow up. The segmentation technique was possible in all patients although erroneous volumes of interest were generated in one patient because of poor fat suppression in the pelvis, requiring manual correction. Responding patients showed a larger increase in gADC (median change = +0.18, range = -0.07 to +0.78 × 10(-3 mm2/s after treatment compared to non-responding patients (median change = -0.02, range = -0.10 to +0.05 × 10(-3 mm2/s, p = 0.05, Mann-Whitney test, whereas non-responding patients showed a significantly larger increase in tDV (median change = +26%, range = +3 to +284% compared to responding patients (median change = -50%, range = -85 to +27%, p = 0.02, Mann-Whitney test. Semi-automatic segmentation of WBDWI is feasible for metastatic bone disease in this pilot cohort of 11 patients, and could be used to quantify tumor total diffusion volume and median global ADC for assessing response to treatment.

  4. Adjustment of Measurements with Multiplicative Errors: Error Analysis, Estimates of the Variance of Unit Weight, and Effect on Volume Estimation from LiDAR-Type Digital Elevation Models

    Directory of Open Access Journals (Sweden)

    Yun Shi

    2014-01-01

    Full Text Available Modern observation technology has verified that measurement errors can be proportional to the true values of measurements such as GPS, VLBI baselines and LiDAR. Observational models of this type are called multiplicative error models. This paper is to extend the work of Xu and Shimada published in 2000 on multiplicative error models to analytical error analysis of quantities of practical interest and estimates of the variance of unit weight. We analytically derive the variance-covariance matrices of the three least squares (LS adjustments, the adjusted measurements and the corrections of measurements in multiplicative error models. For quality evaluation, we construct five estimators for the variance of unit weight in association of the three LS adjustment methods. Although LiDAR measurements are contaminated with multiplicative random errors, LiDAR-based digital elevation models (DEM have been constructed as if they were of additive random errors. We will simulate a model landslide, which is assumed to be surveyed with LiDAR, and investigate the effect of LiDAR-type multiplicative error measurements on DEM construction and its effect on the estimate of landslide mass volume from the constructed DEM.

  5. On Averaging Rotations

    DEFF Research Database (Denmark)

    Gramkow, Claus

    2001-01-01

    In this paper two common approaches to averaging rotations are compared to a more advanced approach based on a Riemannian metric. Very often the barycenter of the quaternions or matrices that represent the rotations are used as an estimate of the mean. These methods neglect that rotations belong ...... approximations to the Riemannian metric, and that the subsequent corrections are inherent in the least squares estimation.......In this paper two common approaches to averaging rotations are compared to a more advanced approach based on a Riemannian metric. Very often the barycenter of the quaternions or matrices that represent the rotations are used as an estimate of the mean. These methods neglect that rotations belong...

  6. Average is Over

    Science.gov (United States)

    Eliazar, Iddo

    2018-02-01

    The popular perception of statistical distributions is depicted by the iconic bell curve which comprises of a massive bulk of 'middle-class' values, and two thin tails - one of small left-wing values, and one of large right-wing values. The shape of the bell curve is unimodal, and its peak represents both the mode and the mean. Thomas Friedman, the famous New York Times columnist, recently asserted that we have entered a human era in which "Average is Over" . In this paper we present mathematical models for the phenomenon that Friedman highlighted. While the models are derived via different modeling approaches, they share a common foundation. Inherent tipping points cause the models to phase-shift from a 'normal' bell-shape statistical behavior to an 'anomalous' statistical behavior: the unimodal shape changes to an unbounded monotone shape, the mode vanishes, and the mean diverges. Hence: (i) there is an explosion of small values; (ii) large values become super-large; (iii) 'middle-class' values are wiped out, leaving an infinite rift between the small and the super large values; and (iv) "Average is Over" indeed.

  7. Average nuclear surface properties

    International Nuclear Information System (INIS)

    Groote, H. von.

    1979-01-01

    The definition of the nuclear surface energy is discussed for semi-infinite matter. This definition is extended also for the case that there is a neutron gas instead of vacuum on the one side of the plane surface. The calculations were performed with the Thomas-Fermi Model of Syler and Blanchard. The parameters of the interaction of this model were determined by a least squares fit to experimental masses. The quality of this fit is discussed with respect to nuclear masses and density distributions. The average surface properties were calculated for different particle asymmetry of the nucleon-matter ranging from symmetry beyond the neutron-drip line until the system no longer can maintain the surface boundary and becomes homogeneous. The results of the calculations are incorporated in the nuclear Droplet Model which then was fitted to experimental masses. (orig.)

  8. Americans' Average Radiation Exposure

    International Nuclear Information System (INIS)

    2000-01-01

    We live with radiation every day. We receive radiation exposures from cosmic rays, from outer space, from radon gas, and from other naturally radioactive elements in the earth. This is called natural background radiation. It includes the radiation we get from plants, animals, and from our own bodies. We also are exposed to man-made sources of radiation, including medical and dental treatments, television sets and emission from coal-fired power plants. Generally, radiation exposures from man-made sources are only a fraction of those received from natural sources. One exception is high exposures used by doctors to treat cancer patients. Each year in the United States, the average dose to people from natural and man-made radiation sources is about 360 millirem. A millirem is an extremely tiny amount of energy absorbed by tissues in the body

  9. Comparison of two-dimensional fast spin echo T2 weighted sequences and three-dimensional volume isotropic T2 weighted fast spin echo (VISTA) MRI in the evaluation of triangular fibrocartilage of the wrist.

    Science.gov (United States)

    Park, Hee Jin; Lee, So Yeon; Kang, Kyung A; Kim, Eun Young; Shin, Hun Kyu; Park, Se Jin; Park, Jai Hyung; Kim, Eugene

    2018-04-01

    To compare image quality of three-dimensional volume isotropic T 2 weighted fast spin echo (3D VISTA) and two-dimensional (2D) T 2 weighted images (T2WI) for evaluation of triangular fibrocartilage (TFC) and to investigate whether 3D VISTA can replace 2D T 2 WI in evaluating TFC injury. This retrospective study included 69 patients who received wrist MRIs using both 2D T 2 WI and 3D VISTA techniques for assessment of wrist pathology, including TFC injury. Two radiologists measured the signal-to-noise ratio (SNR) and the contrast-to-noise ratio (CNR) of the two sequences. The anatomical identification score and diagnostic performance were independently assessed by two interpreters. The diagnostic abilities of 3D VISTA and 2D T 2 WI were analysed by sensitivity, specificity and accuracy for diagnosing TFC injury using surgically or clinically confirmed diagnostic reference standards. 17 cases (25%) were classified as having TFC injury. 2 cases (12%) were diagnosed surgically, and 15 cases (88%) were diagnosed by physical examination. 52 cases (75%) were diagnosed as having intact TFC. 8 of these cases (15%) were surgically confirmed, while the others were diagnosed by physical examination and clinical findings. The 3D VISTA images had significantly higher SNR and CNR values for the TFC than 2D T 2 WI images. The scores of 3D VISTA's total length, full width and sharpness were similar to those of 2D T 2 WI. We were unable to find a significant difference between 3D VISTA and 2D T 2 WI in the ability to diagnose TFC injury. 3D VISTA image quality is similar to that of 2D T 2 WI for TFC evaluation and is also excellent for tissue contrast. 3D VISTA can replace 2D images in TFC injury assessment. Advances in knowledge: 3D VISTA image quality is similar to that of 2D T 2 WI for TFC evaluation and is also excellent for tissue contrast. 3D VISTA can replace 2D images in TFC injury assessment.

  10. Average Bandwidth Allocation Model of WFQ

    Directory of Open Access Journals (Sweden)

    Tomáš Balogh

    2012-01-01

    Full Text Available We present a new iterative method for the calculation of average bandwidth assignment to traffic flows using a WFQ scheduler in IP based NGN networks. The bandwidth assignment calculation is based on the link speed, assigned weights, arrival rate, and average packet length or input rate of the traffic flows. We prove the model outcome with examples and simulation results using NS2 simulator.

  11. Detection the changes of hippocampal volume and the lateral ventricle vein in the patients with depression with susceptibility weighted imaging and morphological measurement

    International Nuclear Information System (INIS)

    Song Huihui; Li Yuefeng; Wang Dongqing; Wei Chuanshe; Duan Ruigen; Zhao Tian; Zhao Liang; Jiang Ping

    2013-01-01

    Objective: To study the hippocampal structure in the patients with depression in varying degrees of severity with the combination of the susceptibility weighted imaging (SWI) and morphological measurement. Methods: Sixty patients (divided equally into mild, moderate and major group as the conditions of the severity of depression) and 20 healthy controls were scanned using the three dimensional fast low angle shot imaging sequence (3D-FLASH) and SWI. Then the morphological images were manually segmented and delineated by three doctors. The hippocampal volumes were calculated and standardized. The maximum diameter, length and the branching numbers of the Inferior ventricular vein which were clear demonstrated in the SWI were measured. The changes in the venous system and morphology among the three different degrees of severity in depression and the healthy controls were contrastively analyzed by the one-way analysis of variance. Results: Left and right hippocampal volumes: the mild group were 2246 ± 147, 2271 ± 151; the moderate group were 2028 ± 65, 2038 ± 57; the major group were 1965 ± 129, 1962 ± 110; the healthy control were 2287 ± 160, 2305 ± 171. There were statistically significant differences among the four groups (F = 7.45, 8.55, P 0.05). The diameter,length and branch numbers of the lateral ventricle vein: the mild group were (0.94 ± 0.09) mm, (12.0 ± 1.07) mm and 3.67 ± 1.03 ; the moderate group were (0.81 ± 0.04) mm, (10.2 ± 1.25) mm and 2.00 ± 0.89 ; the major group were (0.70 ± 0.08) mm, (8.6 ± 1.40) mm and 1.83 ± 0.75 ; the healthy control were (1.15 ± 0.14) mm, (14.2 ± 0.90) mm and 3.33 ± 0.82. There were statistically significant differences among the four groups (F = 17.07, 25.20, 6.65, P 0.05). As the progressive of the depression, the reduction in the length, diameter and branch numbers of the lateral ventricle vein showed more evident (the Dunnett-t of the moderate were -10.20, -11.50, -2.88, P < 0.05 ; the Dunnett-t of the

  12. Essays on model averaging and political economics

    NARCIS (Netherlands)

    Wang, W.

    2013-01-01

    This thesis first investigates various issues related with model averaging, and then evaluates two policies, i.e. West Development Drive in China and fiscal decentralization in U.S, using econometric tools. Chapter 2 proposes a hierarchical weighted least squares (HWALS) method to address multiple

  13. Nutrient Composition and Weight Evaluation of some Newly ...

    African Journals Online (AJOL)

    The average weight ranged between 28.2 in improved white dent to 29.8 in improved yellow dent. The yellow dent variety will be particularly useful in improving level of micronutrient intake. The Journal of Food Technology in Africa Volume 7 No.1, 2002, pp. 27-29. KEY WORDS: Nutrient composition, white dent, yellow dent ...

  14. Estimating volumes of the pituitary gland from T1-weighted magnetic-resonance images: effects of age, puberty, testosterone, and estradiol.

    Science.gov (United States)

    Wong, Angelita Pui-Yee; Pipitone, Jon; Park, Min Tae M; Dickie, Erin W; Leonard, Gabriel; Perron, Michel; Pike, Bruce G; Richer, Louis; Veillette, Suzanne; Chakravarty, M Mallar; Pausova, Zdenka; Paus, Tomáš

    2014-07-01

    The pituitary gland is a key structure in the hypothalamic-pituitary-gonadal (HPG) axis--it plays an important role in sexual maturation during puberty. Despite its small size, its volume can be quantified using magnetic resonance imaging (MRI). Here, we study a cohort of 962 typically developing adolescents from the Saguenay Youth Study and estimate pituitary volumes using a newly developed multi-atlas segmentation method known as the MAGeT Brain algorithm. We found that age and puberty stage (controlled for age) each predicts adjusted pituitary volumes (controlled for total brain volume) in both males and females. Controlling for the effects of age and puberty stage, total testosterone and estradiol levels also predict adjusted pituitary volumes in males and pre-menarche females, respectively. These findings demonstrate that the pituitary gland grows during adolescence, and its volume relates to circulating plasma-levels of sex steroids in both males and females. Copyright © 2014 Elsevier Inc. All rights reserved.

  15. A practical guide to averaging functions

    CERN Document Server

    Beliakov, Gleb; Calvo Sánchez, Tomasa

    2016-01-01

    This book offers an easy-to-use and practice-oriented reference guide to mathematical averages. It presents different ways of aggregating input values given on a numerical scale, and of choosing and/or constructing aggregating functions for specific applications. Building on a previous monograph by Beliakov et al. published by Springer in 2007, it outlines new aggregation methods developed in the interim, with a special focus on the topic of averaging aggregation functions. It examines recent advances in the field, such as aggregation on lattices, penalty-based aggregation and weakly monotone averaging, and extends many of the already existing methods, such as: ordered weighted averaging (OWA), fuzzy integrals and mixture functions. A substantial mathematical background is not called for, as all the relevant mathematical notions are explained here and reported on together with a wealth of graphical illustrations of distinct families of aggregation functions. The authors mainly focus on practical applications ...

  16. Plasma and blood volume in the calf from birth till 90 days of age

    International Nuclear Information System (INIS)

    Moellerberg, L.; Ekman, L.; Jacobsson, S.-O.

    1975-01-01

    Determinations of plasma volume were made of 9 clinically healthy Swedish Red and White calves from birth to 90 days of age by means of the isotop dilution technique. Commercially available 131 I labelled human serum albumin was used. Calculation of the total blood volume was based on the plasma volume and packed cell volume. The plasma and blood volumes increased per kg body weight in average 17 and 14 percent respectively from directly after birth to 24 hrs. old. From 1 to 90 days of age the plasma and blood volume fell steadily per kg body weight. Plasma volume expressed as a percentage of body weight was 5.3 percent at birth, 6.5 percent at 1 day old, and 4.9 percent at 90 days old. Corresponding values for blood were 8.4, 9.3 and 7.0 percent. (author)

  17. All rights reserved Variation in Body Weight, Organ Weight and ...

    African Journals Online (AJOL)

    ADOWIE PERE

    Variation in Body Weight, Organ Weight and Haematological Parameters of Rats Fed ... ABSTRACT: Food insecurity is a major problem of the developing nations. ... Except for the values of haemoglobin and packed cell volume that were ...

  18. Averaging processes in granular flows driven by gravity

    Science.gov (United States)

    Rossi, Giulia; Armanini, Aronne

    2016-04-01

    One of the more promising theoretical frames to analyse the two-phase granular flows is offered by the similarity of their rheology with the kinetic theory of gases [1]. Granular flows can be considered a macroscopic equivalent of the molecular case: the collisions among molecules are compared to the collisions among grains at a macroscopic scale [2,3]. However there are important statistical differences in dealing with the two applications. In the two-phase fluid mechanics, there are two main types of average: the phasic average and the mass weighed average [4]. The kinetic theories assume that the size of atoms is so small, that the number of molecules in a control volume is infinite. With this assumption, the concentration (number of particles n) doesn't change during the averaging process and the two definitions of average coincide. This hypothesis is no more true in granular flows: contrary to gases, the dimension of a single particle becomes comparable to that of the control volume. For this reason, in a single realization the number of grain is constant and the two averages coincide; on the contrary, for more than one realization, n is no more constant and the two types of average lead to different results. Therefore, the ensamble average used in the standard kinetic theory (which usually is the phasic average) is suitable for the single realization, but not for several realization, as already pointed out in [5,6]. In the literature, three main length scales have been identified [7]: the smallest is the particles size, the intermediate consists in the local averaging (in order to describe some instability phenomena or secondary circulation) and the largest arises from phenomena such as large eddies in turbulence. Our aim is to solve the intermediate scale, by applying the mass weighted average, when dealing with more than one realizations. This statistical approach leads to additional diffusive terms in the continuity equation: starting from experimental

  19. The effect of holiday weight gain on body weight.

    Science.gov (United States)

    Schoeller, Dale A

    2014-07-01

    The topic of holiday weight gain has been a frequent subject of the lay media; however, scientific interest has only been recent. Multiple studies in Western societies have reported average weight gains among adults during the period between mid-November and mid-January that were about 0.5 kg. The range in individual weight changes was large, however, and the already overweight and obese gain more weight than those who are healthy weight. When the average gain across the year was also measured, the holiday weight was the major contributor to annual excess weight gain. Efforts patterned to increase awareness to energy balance and body weight have been shown to be successful at reducing such gain. An exception to holiday weight gain being a major contributor to annual excess gain has been children, in whom summer weight gains have been observed to be the major contributor to average excess weight gain. Copyright © 2014 Elsevier Inc. All rights reserved.

  20. Changes in body weight, C-reactive protein, and total adiponectin in non-obese women after 12 months of a small-volume, home-based exercise program.

    Science.gov (United States)

    Mediano, Mauro Felippe Felix; Neves, Fabiana Alves; Cunha, Alessandra Cordeiro de Souza Rodrigues; Souza, Erica Patricia Garcia de; Moura, Anibal Sanchez; Sichieri, Rosely

    2013-01-01

    Our objective was to evaluate the effects of small-volume, home-based exercise combined with slight caloric restriction on the inflammatory markers C-reactive protein and adiponectin. In total, 54 women were randomly assigned to one of two groups for exercise intervention: the control or home-based exercise groups. Weight, waist and hip circumferences, and inflammatory markers were measured at baseline and after 6 and 12 months. Women allocated to the home-based exercise group received a booklet explaining the physical exercises to be practiced at home at least 3 times per week, 40 minutes per session, at low-to-moderate intensity. All participants received dietary counseling aimed at reducing caloric intake by 100-300 calories per day, with a normal distribution of macro-nutrients (26-28% of energy as fat). Clinicaltrials.gov: NCT01206413 RESULTS: The home-based exercise group showed a significantly greater reduction in weight and body mass index at six months, but no difference between groups was observed thereafter. With regard to the inflammatory markers, a greater but non-statistically significant reduction was found for C-reactive protein in the home-based exercise group at six months; however, this difference disappeared after adjusting for weight change. No differences in adiponectin were found at the 6- or 12-month follow-up. Small-volume, home-based exercise did not promote changes in inflammatory markers independent of weight change.

  1. The flattening of the average potential in models with fermions

    International Nuclear Information System (INIS)

    Bornholdt, S.

    1993-01-01

    The average potential is a scale dependent scalar effective potential. In a phase with spontaneous symmetry breaking its inner region becomes flat as the averaging extends over infinite volume and the average potential approaches the convex effective potential. Fermion fluctuations affect the shape of the average potential in this region and its flattening with decreasing physical scale. They have to be taken into account to find the true minimum of the scalar potential which determines the scale of spontaneous symmetry breaking. (orig.)

  2. Dictionary Based Segmentation in Volumes

    DEFF Research Database (Denmark)

    Emerson, Monica Jane; Jespersen, Kristine Munk; Jørgensen, Peter Stanley

    2015-01-01

    We present a method for supervised volumetric segmentation based on a dictionary of small cubes composed of pairs of intensity and label cubes. Intensity cubes are small image volumes where each voxel contains an image intensity. Label cubes are volumes with voxelwise probabilities for a given...... label. The segmentation process is done by matching a cube from the volume, of the same size as the dictionary intensity cubes, to the most similar intensity dictionary cube, and from the associated label cube we get voxel-wise label probabilities. Probabilities from overlapping cubes are averaged...... and hereby we obtain a robust label probability encoding. The dictionary is computed from labeled volumetric image data based on weighted clustering. We experimentally demonstrate our method using two data sets from material science – a phantom data set of a solid oxide fuel cell simulation for detecting...

  3. The impact of using weight estimated from mammographic images vs. self-reported weight on breast cancer risk calculation

    Science.gov (United States)

    Nair, Kalyani P.; Harkness, Elaine F.; Gadde, Soujanye; Lim, Yit Y.; Maxwell, Anthony J.; Moschidis, Emmanouil; Foden, Philip; Cuzick, Jack; Brentnall, Adam; Evans, D. Gareth; Howell, Anthony; Astley, Susan M.

    2017-03-01

    Personalised breast screening requires assessment of individual risk of breast cancer, of which one contributory factor is weight. Self-reported weight has been used for this purpose, but may be unreliable. We explore the use of volume of fat in the breast, measured from digital mammograms. Volumetric breast density measurements were used to determine the volume of fat in the breasts of 40,431 women taking part in the Predicting Risk Of Cancer At Screening (PROCAS) study. Tyrer-Cuzick risk using self-reported weight was calculated for each woman. Weight was also estimated from the relationship between self-reported weight and breast fat volume in the cohort, and used to re-calculate Tyrer-Cuzick risk. Women were assigned to risk categories according to 10 year risk (below average =8%) and the original and re-calculated Tyrer-Cuzick risks were compared. Of the 716 women diagnosed with breast cancer during the study, 15 (2.1%) moved into a lower risk category, and 37 (5.2%) moved into a higher category when using weight estimated from breast fat volume. Of the 39,715 women without a cancer diagnosis, 1009 (2.5%) moved into a lower risk category, and 1721 (4.3%) into a higher risk category. The majority of changes were between below average and average risk categories (38.5% of those with a cancer diagnosis, and 34.6% of those without). No individual moved more than one risk group. Automated breast fat measures may provide a suitable alternative to self-reported weight for risk assessment in personalized screening.

  4. Models for predicting objective function weights in prostate cancer IMRT

    International Nuclear Information System (INIS)

    Boutilier, Justin J.; Lee, Taewoo; Craig, Tim; Sharpe, Michael B.; Chan, Timothy C. Y.

    2015-01-01

    Purpose: To develop and evaluate the clinical applicability of advanced machine learning models that simultaneously predict multiple optimization objective function weights from patient geometry for intensity-modulated radiation therapy of prostate cancer. Methods: A previously developed inverse optimization method was applied retrospectively to determine optimal objective function weights for 315 treated patients. The authors used an overlap volume ratio (OV) of bladder and rectum for different PTV expansions and overlap volume histogram slopes (OVSR and OVSB for the rectum and bladder, respectively) as explanatory variables that quantify patient geometry. Using the optimal weights as ground truth, the authors trained and applied three prediction models: logistic regression (LR), multinomial logistic regression (MLR), and weighted K-nearest neighbor (KNN). The population average of the optimal objective function weights was also calculated. Results: The OV at 0.4 cm and OVSR at 0.1 cm features were found to be the most predictive of the weights. The authors observed comparable performance (i.e., no statistically significant difference) between LR, MLR, and KNN methodologies, with LR appearing to perform the best. All three machine learning models outperformed the population average by a statistically significant amount over a range of clinical metrics including bladder/rectum V53Gy, bladder/rectum V70Gy, and dose to the bladder, rectum, CTV, and PTV. When comparing the weights directly, the LR model predicted bladder and rectum weights that had, on average, a 73% and 74% relative improvement over the population average weights, respectively. The treatment plans resulting from the LR weights had, on average, a rectum V70Gy that was 35% closer to the clinical plan and a bladder V70Gy that was 29% closer, compared to the population average weights. Similar results were observed for all other clinical metrics. Conclusions: The authors demonstrated that the KNN and MLR

  5. Models for predicting objective function weights in prostate cancer IMRT

    Energy Technology Data Exchange (ETDEWEB)

    Boutilier, Justin J., E-mail: j.boutilier@mail.utoronto.ca; Lee, Taewoo [Department of Mechanical and Industrial Engineering, University of Toronto, 5 King’s College Road, Toronto, Ontario M5S 3G8 (Canada); Craig, Tim [Radiation Medicine Program, UHN Princess Margaret Cancer Centre, 610 University of Avenue, Toronto, Ontario M5T 2M9, Canada and Department of Radiation Oncology, University of Toronto, 148 - 150 College Street, Toronto, Ontario M5S 3S2 (Canada); Sharpe, Michael B. [Radiation Medicine Program, UHN Princess Margaret Cancer Centre, 610 University of Avenue, Toronto, Ontario M5T 2M9 (Canada); Department of Radiation Oncology, University of Toronto, 148 - 150 College Street, Toronto, Ontario M5S 3S2 (Canada); Techna Institute for the Advancement of Technology for Health, 124 - 100 College Street, Toronto, Ontario M5G 1P5 (Canada); Chan, Timothy C. Y. [Department of Mechanical and Industrial Engineering, University of Toronto, 5 King’s College Road, Toronto, Ontario M5S 3G8, Canada and Techna Institute for the Advancement of Technology for Health, 124 - 100 College Street, Toronto, Ontario M5G 1P5 (Canada)

    2015-04-15

    Purpose: To develop and evaluate the clinical applicability of advanced machine learning models that simultaneously predict multiple optimization objective function weights from patient geometry for intensity-modulated radiation therapy of prostate cancer. Methods: A previously developed inverse optimization method was applied retrospectively to determine optimal objective function weights for 315 treated patients. The authors used an overlap volume ratio (OV) of bladder and rectum for different PTV expansions and overlap volume histogram slopes (OVSR and OVSB for the rectum and bladder, respectively) as explanatory variables that quantify patient geometry. Using the optimal weights as ground truth, the authors trained and applied three prediction models: logistic regression (LR), multinomial logistic regression (MLR), and weighted K-nearest neighbor (KNN). The population average of the optimal objective function weights was also calculated. Results: The OV at 0.4 cm and OVSR at 0.1 cm features were found to be the most predictive of the weights. The authors observed comparable performance (i.e., no statistically significant difference) between LR, MLR, and KNN methodologies, with LR appearing to perform the best. All three machine learning models outperformed the population average by a statistically significant amount over a range of clinical metrics including bladder/rectum V53Gy, bladder/rectum V70Gy, and dose to the bladder, rectum, CTV, and PTV. When comparing the weights directly, the LR model predicted bladder and rectum weights that had, on average, a 73% and 74% relative improvement over the population average weights, respectively. The treatment plans resulting from the LR weights had, on average, a rectum V70Gy that was 35% closer to the clinical plan and a bladder V70Gy that was 29% closer, compared to the population average weights. Similar results were observed for all other clinical metrics. Conclusions: The authors demonstrated that the KNN and MLR

  6. Successful Large-volume Leukapheresis for Hematopoietic Stem Cell Collection in a Very-low-weight Brain Tumor Infant with Coagulopathy

    Directory of Open Access Journals (Sweden)

    Yu-Mei Liao

    2013-06-01

    Full Text Available Peripheral apheresis has become a safe procedure to collect hematopoietic stem cells, even in pediatric patients and donors. However, the apheresis procedure for small and sick children is more complicated due to difficult venous access, relatively large extracorporeal volume, toxicity of citrate, and unstable hemostasis. We report a small and sick child with refractory medulloblastoma, impaired liver function, and coagulopathy after several major cycles of cisplatin-based chemotherapy. She successfully received large-volume leukapheresis for hematopoietic stem cell collection, although the patient experienced severe coagulopathy during the procedures. Health care providers should be alert to this potential risk.

  7. Regional averaging and scaling in relativistic cosmology

    International Nuclear Information System (INIS)

    Buchert, Thomas; Carfora, Mauro

    2002-01-01

    Averaged inhomogeneous cosmologies lie at the forefront of interest, since cosmological parameters such as the rate of expansion or the mass density are to be considered as volume-averaged quantities and only these can be compared with observations. For this reason the relevant parameters are intrinsically scale-dependent and one wishes to control this dependence without restricting the cosmological model by unphysical assumptions. In the latter respect we contrast our way to approach the averaging problem in relativistic cosmology with shortcomings of averaged Newtonian models. Explicitly, we investigate the scale-dependence of Eulerian volume averages of scalar functions on Riemannian three-manifolds. We propose a complementary view of a Lagrangian smoothing of (tensorial) variables as opposed to their Eulerian averaging on spatial domains. This programme is realized with the help of a global Ricci deformation flow for the metric. We explain rigorously the origin of the Ricci flow which, on heuristic grounds, has already been suggested as a possible candidate for smoothing the initial dataset for cosmological spacetimes. The smoothing of geometry implies a renormalization of averaged spatial variables. We discuss the results in terms of effective cosmological parameters that would be assigned to the smoothed cosmological spacetime. In particular, we find that on the smoothed spatial domain B-bar evaluated cosmological parameters obey Ω-bar B-bar m + Ω-bar B-bar R + Ω-bar B-bar A + Ω-bar B-bar Q 1, where Ω-bar B-bar m , Ω-bar B-bar R and Ω-bar B-bar A correspond to the standard Friedmannian parameters, while Ω-bar B-bar Q is a remnant of cosmic variance of expansion and shear fluctuations on the averaging domain. All these parameters are 'dressed' after smoothing out the geometrical fluctuations, and we give the relations of the 'dressed' to the 'bare' parameters. While the former provide the framework of interpreting observations with a 'Friedmannian bias

  8. Partial volume effect (PVE) on the arterial input function (AIF) in T1-weighted perfusion imaging and limitations of the multiplicative rescaling approach

    DEFF Research Database (Denmark)

    Hansen, Adam Espe; Pedersen, Henrik; Rostrup, Egill

    2009-01-01

    The partial volume effect (PVE) on the arterial input function (AIF) remains a major obstacle to absolute quantification of cerebral blood flow (CBF) using MRI. This study evaluates the validity and performance of a commonly used multiplicative rescaling of the AIF to correct for the PVE. In a gr...

  9. Automatic, accurate, and reproducible segmentation of the brain and cerebro-spinal fluid in T1-weighted volume MRI scans and its application to serial cerebral and intracranial volumetry

    Science.gov (United States)

    Lemieux, Louis

    2001-07-01

    A new fully automatic algorithm for the segmentation of the brain and cerebro-spinal fluid (CSF) from T1-weighted volume MRI scans of the head was specifically developed in the context of serial intra-cranial volumetry. The method is an extension of a previously published brain extraction algorithm. The brain mask is used as a basis for CSF segmentation based on morphological operations, automatic histogram analysis and thresholding. Brain segmentation is then obtained by iterative tracking of the brain-CSF interface. Grey matter (GM), white matter (WM) and CSF volumes are calculated based on a model of intensity probability distribution that includes partial volume effects. Accuracy was assessed using a digital phantom scan. Reproducibility was assessed by segmenting pairs of scans from 20 normal subjects scanned 8 months apart and 11 patients with epilepsy scanned 3.5 years apart. Segmentation accuracy as measured by overlap was 98% for the brain and 96% for the intra-cranial tissues. The volume errors were: total brain (TBV): -1.0%, intra-cranial (ICV):0.1%, CSF: +4.8%. For repeated scans, matching resulted in improved reproducibility. In the controls, the coefficient of reliability (CR) was 1.5% for the TVB and 1.0% for the ICV. In the patients, the Cr for the ICV was 1.2%.

  10. Baseline-dependent averaging in radio interferometry

    Science.gov (United States)

    Wijnholds, S. J.; Willis, A. G.; Salvini, S.

    2018-05-01

    This paper presents a detailed analysis of the applicability and benefits of baseline-dependent averaging (BDA) in modern radio interferometers and in particular the Square Kilometre Array. We demonstrate that BDA does not affect the information content of the data other than a well-defined decorrelation loss for which closed form expressions are readily available. We verify these theoretical findings using simulations. We therefore conclude that BDA can be used reliably in modern radio interferometry allowing a reduction of visibility data volume (and hence processing costs for handling visibility data) by more than 80 per cent.

  11. Predicting objective function weights from patient anatomy in prostate IMRT treatment planning

    International Nuclear Information System (INIS)

    Lee, Taewoo; Hammad, Muhannad; Chan, Timothy C. Y.; Craig, Tim; Sharpe, Michael B.

    2013-01-01

    Purpose: Intensity-modulated radiation therapy (IMRT) treatment planning typically combines multiple criteria into a single objective function by taking a weighted sum. The authors propose a statistical model that predicts objective function weights from patient anatomy for prostate IMRT treatment planning. This study provides a proof of concept for geometry-driven weight determination. Methods: A previously developed inverse optimization method (IOM) was used to generate optimal objective function weights for 24 patients using their historical treatment plans (i.e., dose distributions). These IOM weights were around 1% for each of the femoral heads, while bladder and rectum weights varied greatly between patients. A regression model was developed to predict a patient's rectum weight using the ratio of the overlap volume of the rectum and bladder with the planning target volume at a 1 cm expansion as the independent variable. The femoral head weights were fixed to 1% each and the bladder weight was calculated as one minus the rectum and femoral head weights. The model was validated using leave-one-out cross validation. Objective values and dose distributions generated through inverse planning using the predicted weights were compared to those generated using the original IOM weights, as well as an average of the IOM weights across all patients. Results: The IOM weight vectors were on average six times closer to the predicted weight vectors than to the average weight vector, usingl 2 distance. Likewise, the bladder and rectum objective values achieved by the predicted weights were more similar to the objective values achieved by the IOM weights. The difference in objective value performance between the predicted and average weights was statistically significant according to a one-sided sign test. For all patients, the difference in rectum V54.3 Gy, rectum V70.0 Gy, bladder V54.3 Gy, and bladder V70.0 Gy values between the dose distributions generated by the

  12. Averaging models: parameters estimation with the R-Average procedure

    Directory of Open Access Journals (Sweden)

    S. Noventa

    2010-01-01

    Full Text Available The Functional Measurement approach, proposed within the theoretical framework of Information Integration Theory (Anderson, 1981, 1982, can be a useful multi-attribute analysis tool. Compared to the majority of statistical models, the averaging model can account for interaction effects without adding complexity. The R-Average method (Vidotto & Vicentini, 2007 can be used to estimate the parameters of these models. By the use of multiple information criteria in the model selection procedure, R-Average allows for the identification of the best subset of parameters that account for the data. After a review of the general method, we present an implementation of the procedure in the framework of R-project, followed by some experiments using a Monte Carlo method.

  13. Whole-body adipose tissue and lean muscle volumes and their distribution across gender and age: MR-derived normative values in a normal-weight Swiss population.

    Science.gov (United States)

    Ulbrich, Erika J; Nanz, Daniel; Leinhard, Olof Dahlqvist; Marcon, Magda; Fischer, Michael A

    2018-01-01

    To determine age- and gender-dependent whole-body adipose tissue and muscle volumes in healthy Swiss volunteers in Dixon MRI in comparison with anthropometric and bioelectrical impedance (BIA) measurements. Fat-water-separated whole-body 3 Tesla MRI of 80 healthy volunteers (ages 20 to 62 years) with a body mass index (BMI) of 17.5 to 26.2 kg/m 2 (10 men, 10 women per decade). Age and gender-dependent volumes of total adipose tissue (TAT), visceral adipose tissue (VAT), total abdominal subcutaneous adipose tissue (ASAT) and total abdominal adipose tissue (TAAT), and the total lean muscle tissue (TLMT) normalized for body height were determined by semi-automatic segmentation, and correlated with anthropometric and BIA measurements as well as lifestyle parameters. The TAT, ASAT, VAT, and TLMT indexes (TATi, ASATi, VATi, and TLMTi, respectively) (L/m 2  ± standard deviation) for women/men were 6.4 ± 1.8/5.3 ± 1.7, 1.6 ± 0.7/1.2 ± 0.5, 0.4 ± 0.2/0.8 ± 0.5, and 5.6 ± 0.6/7.1 ± 0.7, respectively. The TATi correlated strongly with ASATi (r > 0.93), VATi, BMI and BIA (r > 0.70), and TAATi (r > 0.96), and weak with TLMTi for both genders (r > -0.34). The VAT was the only parameter showing an age dependency (r > 0.32). The BMI and BIA showed strong correlation with all MR-derived adipose tissue volumes. The TAT mass was estimated significantly lower from BIA than from MRI (both genders P muscle volumes might serve as normative values. The estimation of adipose tissue volumes was significantly lower from anthropometric and BIA measurements than from MRI. Magn Reson Med 79:449-458, 2018. © 2017 International Society for Magnetic Resonance in Medicine. © 2017 International Society for Magnetic Resonance in Medicine.

  14. Efeito do creep feeding sobre o desempenho de bezerros e a eficiência reprodutiva de primíparas Nelore, em pastejo Effect of creep feeding on average daily gain and weaning weight of calves and on reproductive efficiency of primiparous Nelore cows under grazing

    Directory of Open Access Journals (Sweden)

    E. Nogueira

    2006-08-01

    Full Text Available Avaliou-se o efeito da suplementação de bezerros em sistema de creep feeding, em pastagens de Brachiaria brizantha, durante o período de amamentação, sobre o ganho médio diário (GMD, peso à desmama (PD e taxa de gestação, em delineamento inteiramente ao acaso, utilizando 102 vacas Nelore (primíparas de baixa condição corporal ao início da estação de monta e seus bezerros, divididos em dois grupos: T1 (n=52, não tratado e T2 (n=50, tratado com suplemento à base de 20% de PB e 75% de NDT. O consumo médio diário estimado no período foi 0,61kg de suplemento/bezerro/dia. Observaram-se diferenças entre T1 e T2 quanto ao PD (P0,05. A suplementação em creep feeding pode aumentar o GMD e o PD de bezerros Nelore, sem alterar a taxa de gestação de primíparas que iniciam a estação de monta com baixa condição corporal.The effect of creep feeding on average daily gain (ADG and weaning weight (WW of calves and pregnancy rate of dams was evaluated in Nelore cattle on Brachiaria Brizantha pasture. In a complete randomized design, calves were divided into two treatments: T1, the control group and T2, in which calves were provided a supplemental diet containing 20% CP and 75% TDN from 92 days after birth until weaning. The 102 primiparous cows were in low body condition at beginning of breeding season. Average daily consumption of the creep ration was 0.61kg per calf. WW averaged 155.10±2.72kg and 163.80±2.53 and for T1 and T2 calves, respectively (P0.05. Thus, creep feeding can improve WW and preweaning ADG of Nelore calves but may not affect pregnancy rate of primiparous cows in low body condition at the start of the mating.

  15. Model averaging, optimal inference and habit formation

    Directory of Open Access Journals (Sweden)

    Thomas H B FitzGerald

    2014-06-01

    Full Text Available Postulating that the brain performs approximate Bayesian inference generates principled and empirically testable models of neuronal function – the subject of much current interest in neuroscience and related disciplines. Current formulations address inference and learning under some assumed and particular model. In reality, organisms are often faced with an additional challenge – that of determining which model or models of their environment are the best for guiding behaviour. Bayesian model averaging – which says that an agent should weight the predictions of different models according to their evidence – provides a principled way to solve this problem. Importantly, because model evidence is determined by both the accuracy and complexity of the model, optimal inference requires that these be traded off against one another. This means an agent’s behaviour should show an equivalent balance. We hypothesise that Bayesian model averaging plays an important role in cognition, given that it is both optimal and realisable within a plausible neuronal architecture. We outline model averaging and how it might be implemented, and then explore a number of implications for brain and behaviour. In particular, we propose that model averaging can explain a number of apparently suboptimal phenomena within the framework of approximate (bounded Bayesian inference, focussing particularly upon the relationship between goal-directed and habitual behaviour.

  16. 40 CFR 80.205 - How is the annual refinery or importer average and corporate pool average sulfur level determined?

    Science.gov (United States)

    2010-07-01

    ... volume of gasoline produced or imported in batch i. Si=The sulfur content of batch i determined under § 80.330. n=The number of batches of gasoline produced or imported during the averaging period. i=Individual batch of gasoline produced or imported during the averaging period. (b) All annual refinery or...

  17. Associação genética da prenhez aos 16 meses com o peso à desmama e o ganho de peso em animais da raça Nelore Genetic associations of heifer pregnancy at 16 months with weaning weight and average daily gain from weaning to yearling in Nellore cattle

    Directory of Open Access Journals (Sweden)

    Luciana Shiotsuki

    2009-07-01

    Full Text Available Objetivou-se verificar a possibilidade de utilização da prenhez de novilhas aos 16 meses (Pr16 como critério de seleção e as possíveis associações genéticas entre prenhez em novilhas aos 16 meses e o peso à desmama (PD e o ganho de peso médio da desmama ao sobreano (GP. Foram realizadas análises uni e bicaracterísticas para estimação dos componentes de co-variância, empregando-se um modelo animal linear para peso à desmama e ganho de peso da desmama ao sobreano e não-linear para Pr16. A estimação dos componentes de variância e da predição dos valores genéticos dos animais foi realizada por Inferência Bayesiana. Distribuições "flat" foram utilizadas para todos os componentes de co-variância. As estimativas de herdabilidade direta para Pr16, PD e GP foram 0,50; 0,24 e 0,15, respectivamente, e a estimativa de herdabilidade materna para o PD, de 0,07. As correlações genéticas foram -0,25 e 0,09 entre Pr16, PD e GP, respectivamente, e a correlação genética entre Pr16 e o efeito genético materno do PD, de 0,29. A herdabilidade da prenhez aos 16 meses indica que essa característica pode ser utilizada como critério de seleção. As correlações genéticas estimadas indicam que a seleção por animais mais pesados à desmama, a longo prazo, pode diminuir a ocorrência de prenhez aos 16 meses de idade. Além disso, a seleção para maior habilidade materna favorece a seleção de animais mais precoces. No entanto, a seleção para ganho de peso da desmama ao sobreano não leva a mudanças genéticas na precocidade sexual em fêmeas.The objective of the present study was to determine the possible use of heifer pregnancy at 16 months (HP16 as a selection criterion and its possible genetic associations with weaning weight (WW and average daily gain from weaning to yearling (ADGWY. Covariance components were estimated by uni and bivariate animal models assuming a linear model for weaning weight and average daily gain from

  18. Interpreting Bivariate Regression Coefficients: Going beyond the Average

    Science.gov (United States)

    Halcoussis, Dennis; Phillips, G. Michael

    2010-01-01

    Statistics, econometrics, investment analysis, and data analysis classes often review the calculation of several types of averages, including the arithmetic mean, geometric mean, harmonic mean, and various weighted averages. This note shows how each of these can be computed using a basic regression framework. By recognizing when a regression model…

  19. Bounds on Average Time Complexity of Decision Trees

    KAUST Repository

    Chikalov, Igor

    2011-01-01

    In this chapter, bounds on the average depth and the average weighted depth of decision trees are considered. Similar problems are studied in search theory [1], coding theory [77], design and analysis of algorithms (e.g., sorting) [38]. For any

  20. 77 FR 74452 - Bus Testing: Calculation of Average Passenger Weight and Test Vehicle Weight

    Science.gov (United States)

    2012-12-14

    ... require FTA to work with bus manufacturers and transit agencies to establish a new pass/ fail standard for... buses from the current value of 150 pounds to a new value of 175 pounds. This increase was proposed to... new pass/fail standards that require a more comprehensive review of its overall bus testing program...

  1. Evaluations of average level spacings

    International Nuclear Information System (INIS)

    Liou, H.I.

    1980-01-01

    The average level spacing for highly excited nuclei is a key parameter in cross section formulas based on statistical nuclear models, and also plays an important role in determining many physics quantities. Various methods to evaluate average level spacings are reviewed. Because of the finite experimental resolution, to detect a complete sequence of levels without mixing other parities is extremely difficult, if not totally impossible. Most methods derive the average level spacings by applying a fit, with different degrees of generality, to the truncated Porter-Thomas distribution for reduced neutron widths. A method that tests both distributions of level widths and positions is discussed extensivey with an example of 168 Er data. 19 figures, 2 tables

  2. Thyroid weight with age

    International Nuclear Information System (INIS)

    Raulier-Fabry, C.; Hammer, R.

    1965-01-01

    A large number of data on thyroid weight of euthyroid subjects have been collected from the literature in this study. The most probable average weight of the gland appears to be 20 g in the adult and 2 g in the newborn. A decrease in weight has been observed during the first year of life (1 g at 6 months) and only in the second year of life the initial birth weight is reached again. The weight curve may be considered as consisting of three straight lines: from 2 to 7, from 7 to 18 and from 18 to 25 years, their slopes being respectively 0.6, 0.9 and 0.5 g/year. The variations in weight of the thyroid during adulthood are sufficiently small to consider it as having constant value between 25 and 55 years. The available information points to a negligible weight difference between sexes. (authors) [fr

  3. Ergodic averages via dominating processes

    DEFF Research Database (Denmark)

    Møller, Jesper; Mengersen, Kerrie

    2006-01-01

    We show how the mean of a monotone function (defined on a state space equipped with a partial ordering) can be estimated, using ergodic averages calculated from upper and lower dominating processes of a stationary irreducible Markov chain. In particular, we do not need to simulate the stationary...... Markov chain and we eliminate the problem of whether an appropriate burn-in is determined or not. Moreover, when a central limit theorem applies, we show how confidence intervals for the mean can be estimated by bounding the asymptotic variance of the ergodic average based on the equilibrium chain....

  4. Weight Management

    Science.gov (United States)

    ... Health Information Weight Management English English Español Weight Management Obesity is a chronic condition that affects more ... Liver (NASH) Heart Disease & Stroke Sleep Apnea Weight Management Topics About Food Portions Bariatric Surgery for Severe ...

  5. High average power supercontinuum sources

    Indian Academy of Sciences (India)

    The physical mechanisms and basic experimental techniques for the creation of high average spectral power supercontinuum sources is briefly reviewed. We focus on the use of high-power ytterbium-doped fibre lasers as pump sources, and the use of highly nonlinear photonic crystal fibres as the nonlinear medium.

  6. Light-Weight Radioisotope Heater Unit Safety Analysis Report (LWRHU-SAR). Volume I. A. Introduction and executive summary. B. Reference Design Document (RDD)

    International Nuclear Information System (INIS)

    Johnson, E.W.

    1985-10-01

    The orbiter and probe portions of the NASA Galileo spacecraft contain components which require auxiliary heat during the mission. To meet these needs, the Department of Energy's (DOE's) Office of Special Nuclear Projects (OSNP) has sponsored the design, fabrication, and testing of a one-watt encapsulated plutonium dioxide-fueled thermal heater named the Light-Weight Radioisotope Heater Unit (LWRHU). This report addresses the radiological risks which might be encountered by people both at the launch area and worldwide should postulate mission failures or malfunctions occur, which would result in the release of the LWRHUs to the environment. Included are data from the design, mission descriptions, postulated accidents with their consequences, test data, and the derived source terms and personnel exposures for the various events

  7. Autoregressive Moving Average Graph Filtering

    OpenAIRE

    Isufi, Elvin; Loukas, Andreas; Simonetto, Andrea; Leus, Geert

    2016-01-01

    One of the cornerstones of the field of signal processing on graphs are graph filters, direct analogues of classical filters, but intended for signals defined on graphs. This work brings forth new insights on the distributed graph filtering problem. We design a family of autoregressive moving average (ARMA) recursions, which (i) are able to approximate any desired graph frequency response, and (ii) give exact solutions for tasks such as graph signal denoising and interpolation. The design phi...

  8. Averaging Robertson-Walker cosmologies

    International Nuclear Information System (INIS)

    Brown, Iain A.; Robbers, Georg; Behrend, Juliane

    2009-01-01

    The cosmological backreaction arises when one directly averages the Einstein equations to recover an effective Robertson-Walker cosmology, rather than assuming a background a priori. While usually discussed in the context of dark energy, strictly speaking any cosmological model should be recovered from such a procedure. We apply the scalar spatial averaging formalism for the first time to linear Robertson-Walker universes containing matter, radiation and dark energy. The formalism employed is general and incorporates systems of multiple fluids with ease, allowing us to consider quantitatively the universe from deep radiation domination up to the present day in a natural, unified manner. Employing modified Boltzmann codes we evaluate numerically the discrepancies between the assumed and the averaged behaviour arising from the quadratic terms, finding the largest deviations for an Einstein-de Sitter universe, increasing rapidly with Hubble rate to a 0.01% effect for h = 0.701. For the ΛCDM concordance model, the backreaction is of the order of Ω eff 0 ≈ 4 × 10 −6 , with those for dark energy models being within a factor of two or three. The impacts at recombination are of the order of 10 −8 and those in deep radiation domination asymptote to a constant value. While the effective equations of state of the backreactions in Einstein-de Sitter, concordance and quintessence models are generally dust-like, a backreaction with an equation of state w eff < −1/3 can be found for strongly phantom models

  9. Cervical Gross Tumor Volume Dose Predicts Local Control Using Magnetic Resonance Imaging/Diffusion-Weighted Imaging—Guided High-Dose-Rate and Positron Emission Tomography/Computed Tomography—Guided Intensity Modulated Radiation Therapy

    Energy Technology Data Exchange (ETDEWEB)

    Dyk, Pawel; Jiang, Naomi; Sun, Baozhou; DeWees, Todd A. [Department of Radiation Oncology, Washington University School of Medicine, St Louis, Missouri (United States); Fowler, Kathryn J.; Narra, Vamsi [Department of Diagnostic Radiology, Mallinckrodt Institute of Radiology, Washington University School of Medicine, St Louis, Missouri (United States); Garcia-Ramirez, Jose L.; Schwarz, Julie K. [Department of Radiation Oncology, Washington University School of Medicine, St Louis, Missouri (United States); Grigsby, Perry W., E-mail: pgrigsby@wustl.edu [Department of Radiation Oncology, Washington University School of Medicine, St Louis, Missouri (United States); Division of Nuclear Medicine, Mallinckrodt Institute of Radiology, Washington University School of Medicine, St Louis, Missouri (United States); Division of Gynecologic Oncology, Mallinckrodt Institute of Radiology, Washington University School of Medicine, St Louis, Missouri (United States); Alvin J. Siteman Cancer Center, Washington University School of Medicine, St Louis, Missouri (United States)

    2014-11-15

    Purpose: Magnetic resonance imaging/diffusion weighted-imaging (MRI/DWI)-guided high-dose-rate (HDR) brachytherapy and {sup 18}F-fluorodeoxyglucose (FDG) — positron emission tomography/computed tomography (PET/CT)-guided intensity modulated radiation therapy (IMRT) for the definitive treatment of cervical cancer is a novel treatment technique. The purpose of this study was to report our analysis of dose-volume parameters predicting gross tumor volume (GTV) control. Methods and Materials: We analyzed the records of 134 patients with International Federation of Gynecology and Obstetrics stages IB1-IVB cervical cancer treated with combined MRI-guided HDR and IMRT from July 2009 to July 2011. IMRT was targeted to the metabolic tumor volume and lymph nodes by use of FDG-PET/CT simulation. The GTV for each HDR fraction was delineated by use of T2-weighted or apparent diffusion coefficient maps from diffusion-weighted sequences. The D100, D90, and Dmean delivered to the GTV from HDR and IMRT were summed to EQD2. Results: One hundred twenty-five patients received all irradiation treatment as planned, and 9 did not complete treatment. All 134 patients are included in this analysis. Treatment failure in the cervix occurred in 24 patients (18.0%). Patients with cervix failures had a lower D100, D90, and Dmean than those who did not experience failure in the cervix. The respective doses to the GTV were 41, 58, and 136 Gy for failures compared with 67, 99, and 236 Gy for those who did not experience failure (P<.001). Probit analysis estimated the minimum D100, D90, and Dmean doses required for ≥90% local control to be 69, 98, and 260 Gy (P<.001). Conclusions: Total dose delivered to the GTV from combined MRI-guided HDR and PET/CT-guided IMRT is highly correlated with local tumor control. The findings can be directly applied in the clinic for dose adaptation to maximize local control.

  10. Medida da freqüência respiratória e do volume corrente para prever a falha na extubação de recém-nascidos de muito baixo peso em ventilação mecânica Evaluation of respiratory rate and tidal volume to predict extubation failure in mechanically ventilated very low birth weight infants

    Directory of Open Access Journals (Sweden)

    Josy Davidson

    2008-03-01

    Full Text Available OBJETIVO: Verificar se a freqüência respiratória (FR, o volume corrente (VC e a relação FR/VC poderiam prever a falha na extubação em recém-nascidos de muito baixo peso submetidos à ventilação mecânica. MÉTODOS: Estudo prospectivo, observacional, de recém-nascidos com idade gestacional OBJECTIVE: To verify if respiratory rate (RR, tidal volume (TV and respiratory rate and tidal volume ratio (RR/TV could predict extubation failure in very low birth weight infants submitted to mechanical ventilation. METHODS: This prospective observational study enrolled newborn infants with gestational age <37 weeks and birth weight <1,500g, mechanically ventilated from birth during 48 hours to 30 days and thought to be ready for extubation. As soon as the physicians decided for extubation, the neonates received endotracheal continuous positive airway pressure (CPAP for 10 minutes while spontaneous RR, TV and RR/TV were measured using a fixed-orifice pneumotachograph positioned between the endotracheal tube and the ventilator circuit. Thereafter, the neonates were extubated to nasal CPAP. Extubation failure was defined as the need for reintubation within 48 hours. RESULTS: Of the 35 studied infants, 20 (57% were successfully extubated and 15 (43% required reintubation. RR and RR/TV before extubation had a trend to be higher in unsuccessfully extubated infants. TV was similar in both groups. Sensitivity and specificity of these parameters as predictors of extubation failure were 50 and 67% respectively for RR, 40 and 67% for TV and 40 and 73% for RR/TV. CONCLUSIONS: RR, TV and RR/TV showed low sensitivity and specificity to predict extubation failure in mechanically ventilated very low birth weight infants.

  11. Mean Platelet Volume, Vitamin D and C Reactive Protein Levels in Normal Weight Children with Primary Snoring and Obstructive Sleep Apnea Syndrome.

    Science.gov (United States)

    Zicari, Anna Maria; Occasi, Francesca; Di Mauro, Federica; Lollobrigida, Valeria; Di Fraia, Marco; Savastano, Vincenzo; Loffredo, Lorenzo; Nicita, Francesco; Spalice, Alberto; Duse, Marzia

    2016-01-01

    Studies on Mean Platelet Volume (MPV) in children with Sleep Disordered Breathing (SDB) report conflicting results and the hypothesis of an intermittent hypoxemia leading to a systemic inflammation is reaching consensus. Vitamin D exerts anti-inflammatory properties and its deficiency has been supposed to play a role in sleep disorders. Emerging interest is rising about Primary Snoring (PS) since it is reasonable that also undetectable alteration of hypoxia might predispose to an increased production of inflammatory mediators. In this perspective, in a group of children affected by SDB, our aim was to investigate MPV, vitamin D and C Reactive Protein (CRP) levels, which had been previously evaluated separately in different studies focused only on Obstructive Sleep Apnea Syndrome (OSAS). We enrolled 137 children: 70 healthy controls (HC), 67 affected by SDB undergoing a polysomnographic evaluation, 22 with a diagnosis of PS and 45 with a diagnosis of OSAS. All patients underwent routine biochemical evaluations including blood cell counts, CRP and vitamin D. Children affected by SDB had a mean age of 8.49±2.19 and were prevalently males (23 females, 34%; 44 males, 66%). MPV levels were higher in OSAS and PS when compared to HC; platelet count (PLT) and CRP levels were higher while Vitamin D levels were lower in children with SDB when compared to HC. MPV levels were correlated with PLT (r = -0.54; pchildren with PS as well as in children with OSAS, and supports the underlying inflammation, hence, highlighting the importance of an early diagnosis of this previously considered benign form of SDB.

  12. Mean Platelet Volume, Vitamin D and C Reactive Protein Levels in Normal Weight Children with Primary Snoring and Obstructive Sleep Apnea Syndrome.

    Directory of Open Access Journals (Sweden)

    Anna Maria Zicari

    Full Text Available Studies on Mean Platelet Volume (MPV in children with Sleep Disordered Breathing (SDB report conflicting results and the hypothesis of an intermittent hypoxemia leading to a systemic inflammation is reaching consensus. Vitamin D exerts anti-inflammatory properties and its deficiency has been supposed to play a role in sleep disorders. Emerging interest is rising about Primary Snoring (PS since it is reasonable that also undetectable alteration of hypoxia might predispose to an increased production of inflammatory mediators. In this perspective, in a group of children affected by SDB, our aim was to investigate MPV, vitamin D and C Reactive Protein (CRP levels, which had been previously evaluated separately in different studies focused only on Obstructive Sleep Apnea Syndrome (OSAS.We enrolled 137 children: 70 healthy controls (HC, 67 affected by SDB undergoing a polysomnographic evaluation, 22 with a diagnosis of PS and 45 with a diagnosis of OSAS. All patients underwent routine biochemical evaluations including blood cell counts, CRP and vitamin D.Children affected by SDB had a mean age of 8.49±2.19 and were prevalently males (23 females, 34%; 44 males, 66%. MPV levels were higher in OSAS and PS when compared to HC; platelet count (PLT and CRP levels were higher while Vitamin D levels were lower in children with SDB when compared to HC. MPV levels were correlated with PLT (r = -0.54; p<0.001, vitamin D (r = -0.39; p<0.001 and CRP (r = 0.21; p<0.01. A multiple regression was run to predict MPV levels from vitamin D, CRP and PLT and these variables significantly predicted MPV (F = 17.42, p<0.0001; adjusted R2 = 0.37. Only platelet count and vitamin D added statistically significantly to the prediction (p<0.05.The present study provides evidence of higher MPV and lower vitamin D levels in children with PS as well as in children with OSAS, and supports the underlying inflammation, hence, highlighting the importance of an early diagnosis of this

  13. Topological quantization of ensemble averages

    International Nuclear Information System (INIS)

    Prodan, Emil

    2009-01-01

    We define the current of a quantum observable and, under well-defined conditions, we connect its ensemble average to the index of a Fredholm operator. The present work builds on a formalism developed by Kellendonk and Schulz-Baldes (2004 J. Funct. Anal. 209 388) to study the quantization of edge currents for continuous magnetic Schroedinger operators. The generalization given here may be a useful tool to scientists looking for novel manifestations of the topological quantization. As a new application, we show that the differential conductance of atomic wires is given by the index of a certain operator. We also comment on how the formalism can be used to probe the existence of edge states

  14. Flexible time domain averaging technique

    Science.gov (United States)

    Zhao, Ming; Lin, Jing; Lei, Yaguo; Wang, Xiufeng

    2013-09-01

    Time domain averaging(TDA) is essentially a comb filter, it cannot extract the specified harmonics which may be caused by some faults, such as gear eccentric. Meanwhile, TDA always suffers from period cutting error(PCE) to different extent. Several improved TDA methods have been proposed, however they cannot completely eliminate the waveform reconstruction error caused by PCE. In order to overcome the shortcomings of conventional methods, a flexible time domain averaging(FTDA) technique is established, which adapts to the analyzed signal through adjusting each harmonic of the comb filter. In this technique, the explicit form of FTDA is first constructed by frequency domain sampling. Subsequently, chirp Z-transform(CZT) is employed in the algorithm of FTDA, which can improve the calculating efficiency significantly. Since the signal is reconstructed in the continuous time domain, there is no PCE in the FTDA. To validate the effectiveness of FTDA in the signal de-noising, interpolation and harmonic reconstruction, a simulated multi-components periodic signal that corrupted by noise is processed by FTDA. The simulation results show that the FTDA is capable of recovering the periodic components from the background noise effectively. Moreover, it can improve the signal-to-noise ratio by 7.9 dB compared with conventional ones. Experiments are also carried out on gearbox test rigs with chipped tooth and eccentricity gear, respectively. It is shown that the FTDA can identify the direction and severity of the eccentricity gear, and further enhances the amplitudes of impulses by 35%. The proposed technique not only solves the problem of PCE, but also provides a useful tool for the fault symptom extraction of rotating machinery.

  15. Weighted Clustering

    DEFF Research Database (Denmark)

    Ackerman, Margareta; Ben-David, Shai; Branzei, Simina

    2012-01-01

    We investigate a natural generalization of the classical clustering problem, considering clustering tasks in which different instances may have different weights.We conduct the first extensive theoretical analysis on the influence of weighted data on standard clustering algorithms in both...... the partitional and hierarchical settings, characterizing the conditions under which algorithms react to weights. Extending a recent framework for clustering algorithm selection, we propose intuitive properties that would allow users to choose between clustering algorithms in the weighted setting and classify...

  16. SU-F-BRD-01: A Logistic Regression Model to Predict Objective Function Weights in Prostate Cancer IMRT

    International Nuclear Information System (INIS)

    Boutilier, J; Chan, T; Lee, T; Craig, T; Sharpe, M

    2014-01-01

    Purpose: To develop a statistical model that predicts optimization objective function weights from patient geometry for intensity-modulation radiotherapy (IMRT) of prostate cancer. Methods: A previously developed inverse optimization method (IOM) is applied retrospectively to determine optimal weights for 51 treated patients. We use an overlap volume ratio (OVR) of bladder and rectum for different PTV expansions in order to quantify patient geometry in explanatory variables. Using the optimal weights as ground truth, we develop and train a logistic regression (LR) model to predict the rectum weight and thus the bladder weight. Post hoc, we fix the weights of the left femoral head, right femoral head, and an artificial structure that encourages conformity to the population average while normalizing the bladder and rectum weights accordingly. The population average of objective function weights is used for comparison. Results: The OVR at 0.7cm was found to be the most predictive of the rectum weights. The LR model performance is statistically significant when compared to the population average over a range of clinical metrics including bladder/rectum V53Gy, bladder/rectum V70Gy, and mean voxel dose to the bladder, rectum, CTV, and PTV. On average, the LR model predicted bladder and rectum weights that are both 63% closer to the optimal weights compared to the population average. The treatment plans resulting from the LR weights have, on average, a rectum V70Gy that is 35% closer to the clinical plan and a bladder V70Gy that is 43% closer. Similar results are seen for bladder V54Gy and rectum V54Gy. Conclusion: Statistical modelling from patient anatomy can be used to determine objective function weights in IMRT for prostate cancer. Our method allows the treatment planners to begin the personalization process from an informed starting point, which may lead to more consistent clinical plans and reduce overall planning time

  17. SU-F-BRD-01: A Logistic Regression Model to Predict Objective Function Weights in Prostate Cancer IMRT

    Energy Technology Data Exchange (ETDEWEB)

    Boutilier, J; Chan, T; Lee, T [University of Toronto, Toronto, Ontario (Canada); Craig, T; Sharpe, M [University of Toronto, Toronto, Ontario (Canada); The Princess Margaret Cancer Centre - UHN, Toronto, ON (Canada)

    2014-06-15

    Purpose: To develop a statistical model that predicts optimization objective function weights from patient geometry for intensity-modulation radiotherapy (IMRT) of prostate cancer. Methods: A previously developed inverse optimization method (IOM) is applied retrospectively to determine optimal weights for 51 treated patients. We use an overlap volume ratio (OVR) of bladder and rectum for different PTV expansions in order to quantify patient geometry in explanatory variables. Using the optimal weights as ground truth, we develop and train a logistic regression (LR) model to predict the rectum weight and thus the bladder weight. Post hoc, we fix the weights of the left femoral head, right femoral head, and an artificial structure that encourages conformity to the population average while normalizing the bladder and rectum weights accordingly. The population average of objective function weights is used for comparison. Results: The OVR at 0.7cm was found to be the most predictive of the rectum weights. The LR model performance is statistically significant when compared to the population average over a range of clinical metrics including bladder/rectum V53Gy, bladder/rectum V70Gy, and mean voxel dose to the bladder, rectum, CTV, and PTV. On average, the LR model predicted bladder and rectum weights that are both 63% closer to the optimal weights compared to the population average. The treatment plans resulting from the LR weights have, on average, a rectum V70Gy that is 35% closer to the clinical plan and a bladder V70Gy that is 43% closer. Similar results are seen for bladder V54Gy and rectum V54Gy. Conclusion: Statistical modelling from patient anatomy can be used to determine objective function weights in IMRT for prostate cancer. Our method allows the treatment planners to begin the personalization process from an informed starting point, which may lead to more consistent clinical plans and reduce overall planning time.

  18. Averaging in the presence of sliding errors

    International Nuclear Information System (INIS)

    Yost, G.P.

    1991-08-01

    In many cases the precision with which an experiment can measure a physical quantity depends on the value of that quantity. Not having access to the true value, experimental groups are forced to assign their errors based on their own measured value. Procedures which attempt to derive an improved estimate of the true value by a suitable average of such measurements usually weight each experiment's measurement according to the reported variance. However, one is in a position to derive improved error estimates for each experiment from the average itself, provided an approximate idea of the functional dependence of the error on the central value is known. Failing to do so can lead to substantial biases. Techniques which avoid these biases without loss of precision are proposed and their performance is analyzed with examples. These techniques are quite general and can bring about an improvement even when the behavior of the errors is not well understood. Perhaps the most important application of the technique is in fitting curves to histograms

  19. Application of average adult Japanese voxel phantoms to evaluation of photon specific absorbed fractions

    International Nuclear Information System (INIS)

    Sato, Kaoru; Manabe, Kentaro; Endo, Akira

    2012-01-01

    Average adult Japanese male (JM-103) and female (JF-103) voxel (volume pixel) phantoms newly constructed at the Japan Atomic Energy Agency (JAEA) have average characteristics of body sizes and organ masses in adult Japanese. In JM-103 and JF-103, several organs and tissues were newly modeled for dose assessments based on tissue weighting factors of the 2007 Recommendations of the International Commission on Radiological Protection(ICRP). In this study, SAFs for thyroid, stomach, lungs and lymphatic nodes of JM-103 and JF-103 phantoms were calculated, and were compared with those of other adult Japanese phantoms based on individual medical images. In most cases, differences in SAFs between JM-103, JF-103 and other phantoms were about several tens percent, and was mainly attributed to mass differences of organs, tissues and contents. Therefore, it was concluded that SAFs of JM-103 and JF-103 represent those of average adult Japanese and that the two phantoms are applied to dose assessment for average adult Japanese on the basis of the 2007 Recommendations. (author)

  20. ORDERED WEIGHTED DISTANCE MEASURE

    Institute of Scientific and Technical Information of China (English)

    Zeshui XU; Jian CHEN

    2008-01-01

    The aim of this paper is to develop an ordered weighted distance (OWD) measure, which is thegeneralization of some widely used distance measures, including the normalized Hamming distance, the normalized Euclidean distance, the normalized geometric distance, the max distance, the median distance and the min distance, etc. Moreover, the ordered weighted averaging operator, the generalized ordered weighted aggregation operator, the ordered weighted geometric operator, the averaging operator, the geometric mean operator, the ordered weighted square root operator, the square root operator, the max operator, the median operator and the min operator axe also the special cases of the OWD measure. Some methods depending on the input arguments are given to determine the weights associated with the OWD measure. The prominent characteristic of the OWD measure is that it can relieve (or intensify) the influence of unduly large or unduly small deviations on the aggregation results by assigning them low (or high) weights. This desirable characteristic makes the OWD measure very suitable to be used in many actual fields, including group decision making, medical diagnosis, data mining, and pattern recognition, etc. Finally, based on the OWD measure, we develop a group decision making approach, and illustrate it with a numerical example.

  1. The average Indian female nose.

    Science.gov (United States)

    Patil, Surendra B; Kale, Satish M; Jaiswal, Sumeet; Khare, Nishant; Math, Mahantesh

    2011-12-01

    This study aimed to delineate the anthropometric measurements of the noses of young women of an Indian population and to compare them with the published ideals and average measurements for white women. This anthropometric survey included a volunteer sample of 100 young Indian women ages 18 to 35 years with Indian parents and no history of previous surgery or trauma to the nose. Standardized frontal, lateral, oblique, and basal photographs of the subjects' noses were taken, and 12 standard anthropometric measurements of the nose were determined. The results were compared with published standards for North American white women. In addition, nine nasal indices were calculated and compared with the standards for North American white women. The nose of Indian women differs significantly from the white nose. All the nasal measurements for the Indian women were found to be significantly different from those for North American white women. Seven of the nine nasal indices also differed significantly. Anthropometric analysis suggests differences between the Indian female nose and the North American white nose. Thus, a single aesthetic ideal is inadequate. Noses of Indian women are smaller and wider, with a less projected and rounded tip than the noses of white women. This study established the nasal anthropometric norms for nasal parameters, which will serve as a guide for cosmetic and reconstructive surgery in Indian women.

  2. Influence of shear flow on the specific volume and the crystalline morphology of isotactic polypropylene

    NARCIS (Netherlands)

    van der Beek, M.H.E.; Peters, G.W.M.; Meijer, H.E.H.

    2006-01-01

    The influence of shear flow on the temperature evolution of the specific volume and the crystalline morphology of two iPP's, differing in weight-averaged molar mass w, was investigated at nonisothermal conditions and elevated pressures, using a custom-designed dilatometer. These conditions are

  3. Effect of tank geometry on its average performance

    Science.gov (United States)

    Orlov, Aleksey A.; Tsimbalyuk, Alexandr F.; Malyugin, Roman V.; Leontieva, Daria A.; Kotelnikova, Alexandra A.

    2018-03-01

    The mathematical model of non-stationary filling of vertical submerged tanks with gaseous uranium hexafluoride is presented in the paper. There are calculations of the average productivity, heat exchange area, and filling time of various volumes tanks with smooth inner walls depending on their "height : radius" ratio as well as the average productivity, degree, and filling time of horizontal ribbing tank with volume 6.10-2 m3 with change central hole diameter of the ribs. It has been shown that the growth of "height / radius" ratio in tanks with smooth inner walls up to the limiting values allows significantly increasing tank average productivity and reducing its filling time. Growth of H/R ratio of tank with volume 1.0 m3 to the limiting values (in comparison with the standard tank having H/R equal 3.49) augments tank productivity by 23.5 % and the heat exchange area by 20%. Besides, we have demonstrated that maximum average productivity and a minimum filling time are reached for the tank with volume 6.10-2 m3 having central hole diameter of horizontal ribs 6.4.10-2 m.

  4. Efeitos ambientais e genéticos sobre escores visuais e ganho de peso à desmama de animais formadores da raça Brangus Environmental and genetic effects on visual scores and average daily weight gain at the weaning of animals used to form the Brangus breed

    Directory of Open Access Journals (Sweden)

    Sandra Aidar de Queiroz

    2009-02-01

    Full Text Available Estudaram-se os efeitos da idade da vaca ao parto e da idade do animal à desmama, bem como os efeitos genéticos aditivo direto e materno e da heterozigose individual, sobre os escores visuais de conformação, precocidade e musculatura e ganho de peso do nascimento à desmama, de animais formadores da raça Brangus. Foram analisados 53.683, 45.136, 52.937 e 56.471 dados de conformação, precocidade e musculatura à desmama e ganho de peso do nascimento à desmama, respectivamente, de animais nascidos entre 1986 e 2002, provenientes do arquivo zootécnico da empresa Gensys Consultores Associados S/C Ltda. Os efeitos de ambiente e genéticos sobre as características em estudo foram analisados pelo método de quadrados mínimos usando modelos matemáticos que incluíram grupo de contemporâneos como variável classificatória e a idade da vaca ao parto, a idade do animal à desmama e os efeitos aditivo direto e materno e da heterozigose individual como co-variáveis. Todos os efeitos incluídos nos modelos afetaram significativamente as características avaliadas, com exceção do efeito da idade da vaca ao parto sobre o ganho de peso do nascimento à desmama e do efeito aditivo materno sobre todas as características estudadas. Os efeitos ambientais e genéticos revelaram-se importantes fontes de variação para as características estudadas e devem, pois, ser considerados na distinção e comparação dos animais para seleção.The objective of this work was to study the effects of age of cow at calving (IPV and age of calf at weaning (IDD as well as the direct additive genetic effects (AD and maternal (AM, and the individual heterozygosity (HI on visual scores of conformation (CD, precocity (PD and musculature (MD and average daily weight gain from birth to weaning (GND, for animals used to form the Brangus breed. The study analyzed 53,683, 45,136, 52,937 and 56,471 records on CD, PD, MD and GND, respectively for animals born from 1986 to

  5. Dosimetric consequences of planning lung treatments on 4DCT average reconstruction to represent a moving tumour

    International Nuclear Information System (INIS)

    Dunn, L.F.; Taylor, M.L.; Kron, T.; Franich, R.

    2010-01-01

    Full text: Anatomic motion during a radiotherapy treatment is one of the more significant challenges in contemporary radiation therapy. For tumours of the lung, motion due to patient respiration makes both accurate planning and dose delivery difficult. One approach is to use the maximum intensity projection (MIP) obtained from a 40 computed tomography (CT) scan and then use this to determine the treatment volume. The treatment is then planned on a 4DCT average reco struction, rather than assuming the entire ITY has a uniform tumour density. This raises the question: how well does planning on a 'blurred' distribution of density with CT values greater than lung density but less than tumour density match the true case of a tumour moving within lung tissue? The aim of this study was to answer this question, determining the dosimetric impact of using a 4D-CT average reconstruction as the basis for a radiotherapy treatment plan. To achieve this, Monte-Carlo sim ulations were undertaken using GEANT4. The geometry consisted of a tumour (diameter 30 mm) moving with a sinusoidal pattern of amplitude = 20 mm. The tumour's excursion occurs within a lung equivalent volume beyond a chest wall interface. Motion was defined parallel to a 6 MY beam. This was then compared to a single oblate tumour of a magnitude determined by the extremes of the tumour motion. The variable density of the 4DCT average tumour is simulated by a time-weighted average, to achieve the observed density gradient. The generic moving tumour geometry is illustrated in the Figure.

  6. Fitting a function to time-dependent ensemble averaged data

    DEFF Research Database (Denmark)

    Fogelmark, Karl; Lomholt, Michael A.; Irbäck, Anders

    2018-01-01

    Time-dependent ensemble averages, i.e., trajectory-based averages of some observable, are of importance in many fields of science. A crucial objective when interpreting such data is to fit these averages (for instance, squared displacements) with a function and extract parameters (such as diffusion...... method, weighted least squares including correlation in error estimation (WLS-ICE), to particle tracking data. The WLS-ICE method is applicable to arbitrary fit functions, and we provide a publically available WLS-ICE software....

  7. Can Beta Blockers Cause Weight Gain?

    Science.gov (United States)

    ... cause weight gain? Can beta blockers cause weight gain? Answers from Sheldon G. Sheps, M.D. Yes. Weight gain can occur as a side effect of some ... and metoprolol (Lopressor, Toprol-XL). The average weight gain is about 2.6 pounds (about 1.2 ...

  8. Early weight loss predicts weight loss treatment response regardless of binge-eating disorder status and pretreatment weight change.

    Science.gov (United States)

    Barnes, Rachel D; Ivezaj, Valentina; Pittman, Brian P; Grilo, Carlos M

    2018-04-10

    Individuals seeking weight loss treatment have diverse pretreatment weight trajectories, and once enrolled, individuals' response to weight loss treatments also varies greatly and may be influenced by the presence of binge-eating disorder (BED). Reported average weight losses may obscure these considerable differences. This study examined whether BED status and different weight-related change variables are associated with successful weight loss treatment outcomes in a controlled treatment study. Participants (N = 89) with overweight/obesity, with and without BED, participated in a 3-month weight loss trial in primary care with 3- and 12-month follow-ups. We tested the prognostic significance of four weight-related change variables (the last supper, early weight loss, pretreatment weight trajectory, weight suppression) on outcomes (weight loss-overall, weight loss-"subsequent," weight loss during second half of treatment). Early weight loss was positively associated with weight loss-overall at post-treatment, and at 3-month and 12-month follow-up. Early weight loss was positively associated with weight loss-subsequent at post-treatment only. No other weight-related variables were significantly associated with weight loss. Models including BED status and treatment condition were not significant. Participants with early weight loss were more likely to continue losing weight, regardless of BED status or treatment condition. The results highlight the importance of early dedication to weight loss treatment to increase the likelihood of positive outcomes. © 2018 Wiley Periodicals, Inc.

  9. Averaging of nonlinearity-managed pulses

    International Nuclear Information System (INIS)

    Zharnitsky, Vadim; Pelinovsky, Dmitry

    2005-01-01

    We consider the nonlinear Schroedinger equation with the nonlinearity management which describes Bose-Einstein condensates under Feshbach resonance. By using an averaging theory, we derive the Hamiltonian averaged equation and compare it with other averaging methods developed for this problem. The averaged equation is used for analytical approximations of nonlinearity-managed solitons

  10. Weight Loss

    Science.gov (United States)

    ... Rights Employment Discrimination Health Care Professionals Law Enforcement Driver's License For Lawyers Food & Fitness Home Food MyFoodAdvisor ... Fit Types of Activity Weight Loss Assess Your Lifestyle Getting Started Food Choices In My Community Home ...

  11. Failure of Noninvasive Ventilation for De Novo Acute Hypoxemic Respiratory Failure: Role of Tidal Volume.

    Science.gov (United States)

    Carteaux, Guillaume; Millán-Guilarte, Teresa; De Prost, Nicolas; Razazi, Keyvan; Abid, Shariq; Thille, Arnaud W; Schortgen, Frédérique; Brochard, Laurent; Brun-Buisson, Christian; Mekontso Dessap, Armand

    2016-02-01

    A low or moderate expired tidal volume can be difficult to achieve during noninvasive ventilation for de novo acute hypoxemic respiratory failure (i.e., not due to exacerbation of chronic lung disease or cardiac failure). We assessed expired tidal volume and its association with noninvasive ventilation outcome. Prospective observational study. Twenty-four bed university medical ICU. Consecutive patients receiving noninvasive ventilation for acute hypoxemic respiratory failure between August 2010 and February 2013. Noninvasive ventilation was uniformly delivered using a simple algorithm targeting the expired tidal volume between 6 and 8 mL/kg of predicted body weight. Expired tidal volume was averaged and respiratory and hemodynamic variables were systematically recorded at each noninvasive ventilation session. Sixty-two patients were enrolled, including 47 meeting criteria for acute respiratory distress syndrome, and 32 failed noninvasive ventilation (51%). Pneumonia (n = 51, 82%) was the main etiology of acute hypoxemic respiratory failure. The median (interquartile range) expired tidal volume averaged over all noninvasive ventilation sessions (mean expired tidal volume) was 9.8 mL/kg predicted body weight (8.1-11.1 mL/kg predicted body weight). The mean expired tidal volume was significantly higher in patients who failed noninvasive ventilation as compared with those who succeeded (10.6 mL/kg predicted body weight [9.6-12.0] vs 8.5 mL/kg predicted body weight [7.6-10.2]; p = 0.001), and expired tidal volume was independently associated with noninvasive ventilation failure in multivariate analysis. This effect was mainly driven by patients with PaO2/FIO2 up to 200 mm Hg. In these patients, the expired tidal volume above 9.5 mL/kg predicted body weight predicted noninvasive ventilation failure with a sensitivity of 82% and a specificity of 87%. A low expired tidal volume is almost impossible to achieve in the majority of patients receiving noninvasive ventilation

  12. Comparison of MRI pulse sequences in defining prostate volume after permanent implantation

    International Nuclear Information System (INIS)

    McLaughlin, P.W.; Narayana, V.; Drake, D.G.; Miller, B.M.; Marsh, L.; Chan, J.; Gonda, R.; Winfield, R.J.; Roberson, P.L.

    2002-01-01

    Purpose: To determine the relative value of three MRI pulse sequences in defining the prostate volume after permanent implantation. Methods and Materials: A total of 45 patients who received a permanent 125 I implant were studied. Two weeks after implantation, an axial CT scan (2 mm thickness) and T 1 -weighted, T 1 -weighted fat saturation, and T 2 -weighted axial MRI (3-mm) studies were obtained. The prostate volumes were compared with the initial ultrasound planning volumes, and subsequently the CT, T 1 -weighted, and T 1 -weighted fat saturation MRI volumes were compared with the T 2 -weighted volumes. Discrepancies in volume were evaluated by visual inspection of the registered axial images and the registration of axial volumes on the sagittal T 2 -weighted volumes. In a limited set of patients, pre- and postimplant CT and T 2 -weighted MRI studies were available for comparison to determine whether prostate volume changes after implant were dependent on the imaging modality. Results: T 1 -weighted and T 1 -weighted fat saturation MRI and CT prostate volumes were consistently larger than the T 2 -weighted MRI prostate volumes, with a volume on average 1.33 (SD 0.24) times the T 2 -weighted volume. This discrepancy was due to the superiority of T 2 -weighted MRI for prostate definition at the following critical interfaces: membranous urethra, apex, and anterior base-bladder and posterior base-seminal vesicle interfaces. The differences in prostate definition in the anterior base region suggest that the commonly reported underdose may be due to overestimation of the prostate in this region by CT. The consistent difference in volumes suggests that the degree of swelling observed after implantation is in part a function of the imaging modality. In patients with pre- and postimplant CT and T 2 -weighted MRI images, swelling on the T 2 -weighted images was 1.1 times baseline and on CT was 1.3 times baseline, confirming the imaging modality dependence of prostate

  13. Comparative Ebulliometry: a Simple, Reliable Technique for Accurate Measurement of the Number Average Molecular Weight of Macromolecules. Preliminary Studies on Heavy Crude Fractions Ébulliométrie comparative : technique simple et fiable pour déterminer précisément la masse molaire moyenne en nombre des macromolécules. Etudes préliminaires sur des fractions lourdes de bruts

    Directory of Open Access Journals (Sweden)

    Behar E.

    2006-12-01

    Full Text Available This article is divided into two parts. In the first part, the authors present a comparison of the major techniques for the measurement of the molecular weight of macromolecules. The bibliographic results are gathered in several tables. In the second part, a comparative ebulliometer for the measurement of the number average molecular weight (Mn of heavy crude oil fractions is described. The high efficiency of the apparatus is demonstrated with a preliminary study of atmospheric distillation residues and resins. The measurement of molecular weights up to 2000 g/mol is possible in less than 4 hours with an uncertainty of about 2%. Cet article comprend deux parties. Dans la première, les auteurs présentent une comparaison entre les principales techniques de détermination de la masse molaire de macromolécules. Les résultats de l'étude bibliographique sont rassemblés dans plusieurs tableaux. La seconde partie décrit un ébulliomètre comparatif conçu pour la mesure de la masse molaire moyenne en nombre (Mn des fractions lourdes des bruts. Une illustration de l'efficacité de cet appareil est indiquée avec l'étude préliminaire de résidus de distillation atmosphérique et de résines. En particulier, la mesure de masses molaires pouvant atteindre 2000 g/mol est possible en moins de 4 heures avec une incertitude expérimentale de l'ordre de 2 %.

  14. SU-E-J-231: Comparison of Delineation Variability of Soft Tissue Volume and Position in Head-And-Neck Between Two T1-Weighted Pulse Sequences Using An MR-Simulator with Immobilization

    Energy Technology Data Exchange (ETDEWEB)

    Wong, O; Lo, G; Yuan, J; Law, M; Ding, A; Cheng, K; Chan, K; Cheung, K; Yu, S [Hong Kong Sanatorium & Hospital, Hong Kong (Hong Kong)

    2015-06-15

    Purpose: There is growing interests in applying MR-simulator(MR-sim) in radiotherapy but MR images subject to hardware, patient and pulse sequence dependent geometric distortion that may potentially influence target definition. This study aimed to evaluate the influence on head-and-neck tissue delineation, in terms of positional and volumetric variability, of two T1-weighted(T1w) MR sequences on a 1.5T MR-sim Methods: Four healthy volunteers were scanned (4 scans for each on different days) using both spin-echo (3DCUBE, TR/TE=500/14ms, TA=183s) and gradient-echo sequences (3DFSPGR, TE/TR=7/4ms, TA=173s) with identical coverage, voxel-size(0.8×0.8×1.0mm3), receiver-bandwidth(62.5kHz/pix) and geometric correction on a 1.5T MR-sim immobilized with personalized thermoplastic cast and head-rest. Under this setting, similar T1w contrast and signal-to-noise ratio were obtained, and factors other than sequence that might bias image distortion and tissue delineation were minimized. VOIs of parotid gland(PGR, PGL), pituitary gland(PIT) and eyeballs(EyeL, EyeR) were carefully drawn, and inter-scan coefficient-of-variation(CV) of VOI centroid position and volume were calculated for each subject. Mean and standard deviation(SD) of the CVs for four subjects were compared between sequences using Wilcoxon ranksum test. Results: The mean positional(<4%) and volumetric(<7%) CVs varied between tissues, majorly dependent on tissue inherent properties like volume, location, mobility and deformability. Smaller mean volumetric CV was found in 3DCUBE, probably due to its less proneness to tissue susceptibility, but only PGL showed significant difference(P<0.05). Positional CVs had no significant differences for all VOIs(P>0.05) between sequences, suggesting volumetric variation might be more sensitive to sequence-dependent delineation difference. Conclusion: Although 3DCUBE is considered less prone to tissue susceptibility-induced artifact and distortion, our preliminary data showed

  15. Diffusion-weighted MR imaging of the normal fetal lung

    International Nuclear Information System (INIS)

    Balassy, Csilla; Kasprian, Gregor; Weber, Michael; Hoermann, Marcus; Bankier, Alexander; Herold, Christian J.; Prayer, Daniela; Brugger, Peter C.; Csapo, Bence; Bammer, Roland

    2008-01-01

    To quantify apparent diffusion coefficient (ADC) changes in fetuses with normal lungs and to determine whether ADC can be used in the assessment of fetal lung development. In 53 pregnancies (20-37th weeks of gestation), we measured ADC on diffusion-weighted imaging (DWI) in the apical, middle, and basal thirds of the right lung. ADCs were correlated with gestational age. Differences between the ADCs were assessed. Fetal lung volumes were measured on T2-weighted sequences and correlated with ADCs and with age. ADCs were 2.13 ± 0.44 μm 2 /ms (mean ± SD) in the apex, 1.99 ± 0.42 μm 2 /ms (mean ± SD) in the middle third, and 1.91 ± 0.41 μm 2 /ms (mean ± SD) in the lung base. Neither the individual ADC values nor average ADC values showed a significant correlation with gestational age or with lung volumes. Average ADCs decreased significantly from the lung apex toward the base. Individual ADCs showed little absolute change and heterogeneity. Lung volumes increased significantly during gestation. We have not been able to identify a pattern of changes in the ADC values that correlate with lung maturation. Furthermore, the individual, gravity-related ADC changes are subject to substantial variability and show nonuniform behavior. ADC can therefore not be used as an indicator of lung maturity. (orig.)

  16. Diffusion-weighted MR imaging of the normal fetal lung

    Energy Technology Data Exchange (ETDEWEB)

    Balassy, Csilla; Kasprian, Gregor; Weber, Michael; Hoermann, Marcus; Bankier, Alexander; Herold, Christian J.; Prayer, Daniela [Medical University of Vienna, Department of Radiology, Vienna (Austria); Brugger, Peter C. [Medical University of Vienna, Center of Anatomy and Cell Biology, Vienna (Austria); Csapo, Bence [Medical University of Vienna, Department of Obstetrics and Gyneocology, Vienna (Austria); Bammer, Roland [University of Stanford, Department of Radiology, Stanford, CA (United States)

    2008-04-15

    To quantify apparent diffusion coefficient (ADC) changes in fetuses with normal lungs and to determine whether ADC can be used in the assessment of fetal lung development. In 53 pregnancies (20-37th weeks of gestation), we measured ADC on diffusion-weighted imaging (DWI) in the apical, middle, and basal thirds of the right lung. ADCs were correlated with gestational age. Differences between the ADCs were assessed. Fetal lung volumes were measured on T2-weighted sequences and correlated with ADCs and with age. ADCs were 2.13 {+-} 0.44 {mu}m{sup 2}/ms (mean {+-} SD) in the apex, 1.99 {+-} 0.42 {mu}m{sup 2}/ms (mean {+-} SD) in the middle third, and 1.91 {+-} 0.41 {mu}m{sup 2}/ms (mean {+-} SD) in the lung base. Neither the individual ADC values nor average ADC values showed a significant correlation with gestational age or with lung volumes. Average ADCs decreased significantly from the lung apex toward the base. Individual ADCs showed little absolute change and heterogeneity. Lung volumes increased significantly during gestation. We have not been able to identify a pattern of changes in the ADC values that correlate with lung maturation. Furthermore, the individual, gravity-related ADC changes are subject to substantial variability and show nonuniform behavior. ADC can therefore not be used as an indicator of lung maturity. (orig.)

  17. Diagnostic examination performance by using microvascular leakage, cerebral blood volume, and blood flow derived from 3-T dynamic susceptibility-weighted contrast-enhanced perfusion MR imaging in the differentiation of glioblastoma multiforme and brain metastasis

    International Nuclear Information System (INIS)

    Server, Andres; Nakstad, Per H.; Orheim, Tone E.D.; Graff, Bjoern A.; Josefsen, Roger; Kumar, Theresa

    2011-01-01

    Conventional magnetic resonance (MR) imaging has limited capacity to differentiate between glioblastoma multiforme (GBM) and metastasis. The purposes of this study were: (1) to compare microvascular leakage (MVL), cerebral blood volume (CBV), and blood flow (CBF) in the distinction of metastasis from GBM using dynamic susceptibility-weighted contrast-enhanced perfusion MR imaging (DSC-MRI), and (2) to estimate the diagnostic accuracy of perfusion and permeability MR imaging. A prospective study of 61 patients (40 GBMs and 21 metastases) was performed at 3 T using DSC-MRI. Normalized rCBV and rCBF from tumoral (rCBVt, rCBFt), peri-enhancing region (rCBVe, rCBFe), and by dividing the value in the tumor by the value in the peri-enhancing region (rCBVt/e, rCBFt/e), as well as MVL were calculated. Hemodynamic and histopathologic variables were analyzed statistically and Spearman/Pearson correlations. Receiver operating characteristic curve analysis was performed for each of the variables. The rCBVe, rCBFe, and MVL were significantly greater in GBMs compared with those of metastases. The optimal cutoff value for differentiating GBM from metastasis was 0.80 which implies a sensitivity of 95%, a specificity of 92%, a positive predictive value of 86%, and a negative predictive value of 97% for rCBVe ratio. We found a modest correlation between rCBVt and rCBFt ratios. MVL measurements in GBMs are significantly higher than those in metastases. Statistically, both rCBVe, rCBVt/e and rCBFe, rCBFt/e were useful in differentiating between GBMs and metastases, supporting the hypothesis that perfusion MR imaging can detect infiltration of tumor cells in the peri-enhancing region. (orig.)

  18. A study to determine whether the volume-weighted computed tomography dose index gives reasonable estimates of organ doses for thai patients undergoing abdomen and pelvis computed tomography examinations

    Directory of Open Access Journals (Sweden)

    Supawitoo Sookpeng

    2017-01-01

    Full Text Available Introduction: Values for the CTDIvol, which is displayed on scanner consoles, give doses relative to a phantom much larger than most Thai patients, and the CTDIvoldoes not take account of differences in patient size, which affect organ doses. Objective: The purpose of this study was to evaluate relationships for size specific dose estimate (SSDE and volume weighted computed tomography (CT dose index (CTDIvol with patient size for CT scanners operating under automatic tube current modulation (ATCM. Methods: Retrospective data from 244 patients who had undergone abdomen and pelvis examination on GE and Siemens CT scanners were included in this study. The combination of anteroposterior (AP and lateral dimensions at the level of the first lumbar vertebra (L1 was used to represent patient size. Image noise within the liver was measured, and values of the absorbed dose for organs covered by the primary beam such as the liver, stomach and kidney were calculated using methods described in the literature. Values of CTDIvolwere recorded and SSDE calculated according to the American Association of Physics in Medicine (AAPM Report No.204. Linear regression models were used to evaluate the relationship between SSDE, CTDIvol, image noise and patient size. Results: SSDE is 20%-50% larger than the CTDIvol, with values for larger patients being more representative. Both the CTDIvoland image noise decreased with patient size for Siemens scanners, but the decline in SSDE was less significant. For the GE scanner, the CTDIvolwas a factor of 3-4 lower in small patients compared to larger ones, while the SSDE only decreased by a factor of two. Noise actually decreased slightly with patient size. Conclusion: Values of SSDE were similar to the doses calculated for the liver, stomach and kidney, which are covered by the primary beam, confirming that it provides a good estimate of organ-absorbed dose.

  19. Diagnostic examination performance by using microvascular leakage, cerebral blood volume, and blood flow derived from 3-T dynamic susceptibility-weighted contrast-enhanced perfusion MR imaging in the differentiation of glioblastoma multiforme and brain metastasis

    Energy Technology Data Exchange (ETDEWEB)

    Server, Andres; Nakstad, Per H. [Oslo University Hospital-Ullevaal, Section of Neuroradiology, Department of Radiology and Nuclear Medicine, Oslo (Norway); University of Oslo, Oslo (Norway); Orheim, Tone E.D. [Oslo University Hospital, Interventional Centre, Oslo (Norway); Graff, Bjoern A. [Oslo University Hospital-Ullevaal, Department of Radiology and Nuclear Medicine, Oslo (Norway); Josefsen, Roger [Oslo University Hospital-Ullevaal, Department of Neurosurgery, Oslo (Norway); Kumar, Theresa [Oslo University Hospital-Ullevaal, Department of Pathology, Oslo (Norway)

    2011-05-15

    Conventional magnetic resonance (MR) imaging has limited capacity to differentiate between glioblastoma multiforme (GBM) and metastasis. The purposes of this study were: (1) to compare microvascular leakage (MVL), cerebral blood volume (CBV), and blood flow (CBF) in the distinction of metastasis from GBM using dynamic susceptibility-weighted contrast-enhanced perfusion MR imaging (DSC-MRI), and (2) to estimate the diagnostic accuracy of perfusion and permeability MR imaging. A prospective study of 61 patients (40 GBMs and 21 metastases) was performed at 3 T using DSC-MRI. Normalized rCBV and rCBF from tumoral (rCBVt, rCBFt), peri-enhancing region (rCBVe, rCBFe), and by dividing the value in the tumor by the value in the peri-enhancing region (rCBVt/e, rCBFt/e), as well as MVL were calculated. Hemodynamic and histopathologic variables were analyzed statistically and Spearman/Pearson correlations. Receiver operating characteristic curve analysis was performed for each of the variables. The rCBVe, rCBFe, and MVL were significantly greater in GBMs compared with those of metastases. The optimal cutoff value for differentiating GBM from metastasis was 0.80 which implies a sensitivity of 95%, a specificity of 92%, a positive predictive value of 86%, and a negative predictive value of 97% for rCBVe ratio. We found a modest correlation between rCBVt and rCBFt ratios. MVL measurements in GBMs are significantly higher than those in metastases. Statistically, both rCBVe, rCBVt/e and rCBFe, rCBFt/e were useful in differentiating between GBMs and metastases, supporting the hypothesis that perfusion MR imaging can detect infiltration of tumor cells in the peri-enhancing region. (orig.)

  20. A SURVEY OF SIZES AND WEIGHTS OF BEMISIA TABACI(HOMOPTERA: ALEYRODIDAE)B BIOTYPE LIFE STAGES FROM FIELD GROWN COTTON AND CANTALOUPES

    Institute of Scientific and Technical Information of China (English)

    Chang-chiChu; JamesS.Buckner; KamilKarut; ThomasP.Freeman; DennisR.Nelson; ThomasJ.Henneberryl

    2003-01-01

    Size and weight measurements were made for all the life stages of Bemisia tabaci (Gennadius) B biotype from field grown cotton ( Gossypium hirsutum L. ) and cantaloupe ( Cucumis melo L., var. cantalupensis )in Phoenix, AZ and Fargo, ND, USA in 2000 and 2001. Nymphal volumes were derived from the measurements.The average nymphal volume increase for settled 1 st to the late 4th instar was exponential. The greatest increase in body volume occurred during development from the 3rd to early 4th instar. Nymphs on cotton leaves were wider,but not longer compared with those on cantaloupe. Ventral and dorsal depth ratios of nymphal bodies from 1st tolate 4th instars from cantaloupe leaves were significantly greater compared with those from cotton leaves. During nymphal development from 1st to 4th instar, the average (from the two host species) ventral body half volume in-creased by nearly 51 times compared with an increase of 28 times for the dorsal body half volume. Adult female and male average lengths, from heads to wing tips, were 1 126 μm and 953 μm, respectively. Average adult fe-male and male weights were 39 and 17 μg, respectively. Average widths, lengths, and weights of eggs from cottonand cantaloupe were, 99 μm, 197 μm, and 0.8 μg, respectively. Average widths, lengths, and weights for exu-viae of non-parasitized nymphs from both cotton and cantaloupe were 492 μm, 673 μm, and 1.20 μg, respective-ly; and widths, lengths, and weights of parasitized nymph exuviae were 452 μm, 665 μm, and 3.62 μg, respec-tively. Both exuviae from non-parasitized and parasitized nymphs from cotton leaves were wider, longer, and heavier than those from cantaloupe leaves.

  1. Bounds on Average Time Complexity of Decision Trees

    KAUST Repository

    Chikalov, Igor

    2011-01-01

    In this chapter, bounds on the average depth and the average weighted depth of decision trees are considered. Similar problems are studied in search theory [1], coding theory [77], design and analysis of algorithms (e.g., sorting) [38]. For any diagnostic problem, the minimum average depth of decision tree is bounded from below by the entropy of probability distribution (with a multiplier 1/log2 k for a problem over a k-valued information system). Among diagnostic problems, the problems with a complete set of attributes have the lowest minimum average depth of decision trees (e.g, the problem of building optimal prefix code [1] and a blood test study in assumption that exactly one patient is ill [23]). For such problems, the minimum average depth of decision tree exceeds the lower bound by at most one. The minimum average depth reaches the maximum on the problems in which each attribute is "indispensable" [44] (e.g., a diagnostic problem with n attributes and kn pairwise different rows in the decision table and the problem of implementing the modulo 2 summation function). These problems have the minimum average depth of decision tree equal to the number of attributes in the problem description. © Springer-Verlag Berlin Heidelberg 2011.

  2. The average size of ordered binary subgraphs

    NARCIS (Netherlands)

    van Leeuwen, J.; Hartel, Pieter H.

    To analyse the demands made on the garbage collector in a graph reduction system, the change in size of an average graph is studied when an arbitrary edge is removed. In ordered binary trees the average number of deleted nodes as a result of cutting a single edge is equal to the average size of a

  3. Healthy Weight

    Science.gov (United States)

    ... such diets limit your nutritional intake, can be unhealthy, and tend to fail in the long run. The key to achieving and maintaining a healthy weight isn't about short-term dietary changes. It's about a lifestyle that includes healthy eating, regular physical activity, and ...

  4. Fitting a function to time-dependent ensemble averaged data.

    Science.gov (United States)

    Fogelmark, Karl; Lomholt, Michael A; Irbäck, Anders; Ambjörnsson, Tobias

    2018-05-03

    Time-dependent ensemble averages, i.e., trajectory-based averages of some observable, are of importance in many fields of science. A crucial objective when interpreting such data is to fit these averages (for instance, squared displacements) with a function and extract parameters (such as diffusion constants). A commonly overlooked challenge in such function fitting procedures is that fluctuations around mean values, by construction, exhibit temporal correlations. We show that the only available general purpose function fitting methods, correlated chi-square method and the weighted least squares method (which neglects correlation), fail at either robust parameter estimation or accurate error estimation. We remedy this by deriving a new closed-form error estimation formula for weighted least square fitting. The new formula uses the full covariance matrix, i.e., rigorously includes temporal correlations, but is free of the robustness issues, inherent to the correlated chi-square method. We demonstrate its accuracy in four examples of importance in many fields: Brownian motion, damped harmonic oscillation, fractional Brownian motion and continuous time random walks. We also successfully apply our method, weighted least squares including correlation in error estimation (WLS-ICE), to particle tracking data. The WLS-ICE method is applicable to arbitrary fit functions, and we provide a publically available WLS-ICE software.

  5. Effects of gauge volume on pseudo-strain induced in strain measurement using time-of-flight neutron diffraction

    International Nuclear Information System (INIS)

    Suzuki, Hiroshi; Harjo, Stefanus; Abe, Jun; Xu, Pingguang; Aizawa, Kazuya; Akita, Koichi

    2013-01-01

    Spurious or pseudo-strains observed in time-of-flight (TOF) neutron diffraction due to neutron attenuation, surface-effects and a strain distribution within the gauge volume were investigated. Experiments were carried out on annealed and bent ferritic steel bars to test these effects. The most representative position in the gauge volume corresponds to the neutron-weighted center of gravity (ncog), which takes into account variations in intensity within the gauge volume due to neutron attenuation and/or absence of material in the gauge volume. The average strain in the gauge volume was observed to be weighted towards the ncog position but following an increase in the size of the gauge volume the weighted average strain was changed because of the change in the ncog position when a strain gradient appeared within the gauge volume. On the other hand, typical pseudo-strains, which are well known, did appear in through-surface strain measurements when the gauge volume was incompletely filled by the sample. Tensile pseudo-strains due to the surface-effect increased near the sample surface and exhibited a similar trend regardless of the size of the gauge volume, while the pseudo-strains increased faster for the smaller gauge volume. Furthermore, a pseudo-strain due to a change in the ncog position was observed even when the gauge volume was perfectly filled in the sample, and it increased with an increase in the size of the gauge volume. These pseudo-strains measured were much larger than those simulated by the conventional modeling, whereas they were simulated by taking into account an incident neutron beam divergence additionally in the model. Therefore, the incident divergence of the incident neutron beam must be carefully designed to avoid pseudo-strains in time-of-flight neutron diffractometry

  6. Weighted approximation with varying weight

    CERN Document Server

    Totik, Vilmos

    1994-01-01

    A new construction is given for approximating a logarithmic potential by a discrete one. This yields a new approach to approximation with weighted polynomials of the form w"n"(" "= uppercase)P"n"(" "= uppercase). The new technique settles several open problems, and it leads to a simple proof for the strong asymptotics on some L p(uppercase) extremal problems on the real line with exponential weights, which, for the case p=2, are equivalent to power- type asymptotics for the leading coefficients of the corresponding orthogonal polynomials. The method is also modified toyield (in a sense) uniformly good approximation on the whole support. This allows one to deduce strong asymptotics in some L p(uppercase) extremal problems with varying weights. Applications are given, relating to fast decreasing polynomials, asymptotic behavior of orthogonal polynomials and multipoint Pade approximation. The approach is potential-theoretic, but the text is self-contained.

  7. Pancreas segmentation from 3D abdominal CT images using patient-specific weighted subspatial probabilistic atlases

    Science.gov (United States)

    Karasawa, Kenichi; Oda, Masahiro; Hayashi, Yuichiro; Nimura, Yukitaka; Kitasaka, Takayuki; Misawa, Kazunari; Fujiwara, Michitaka; Rueckert, Daniel; Mori, Kensaku

    2015-03-01

    Abdominal organ segmentations from CT volumes are now widely used in the computer-aided diagnosis and surgery assistance systems. Among abdominal organs, the pancreas is especially difficult to segment because of its large individual differences of the shape and position. In this paper, we propose a new pancreas segmentation method from 3D abdominal CT volumes using patient-specific weighted-subspatial probabilistic atlases. First of all, we perform normalization of organ shapes in training volumes and an input volume. We extract the Volume Of Interest (VOI) of the pancreas from the training volumes and an input volume. We divide each training VOI and input VOI into some cubic regions. We use a nonrigid registration method to register these cubic regions of the training VOI to corresponding regions of the input VOI. Based on the registration results, we calculate similarities between each cubic region of the training VOI and corresponding region of the input VOI. We select cubic regions of training volumes having the top N similarities in each cubic region. We subspatially construct probabilistic atlases weighted by the similarities in each cubic region. After integrating these probabilistic atlases in cubic regions into one, we perform a rough-to-precise segmentation of the pancreas using the atlas. The results of the experiments showed that utilization of the training volumes having the top N similarities in each cubic region led good results of the pancreas segmentation. The Jaccard Index and the average surface distance of the result were 58.9% and 2.04mm on average, respectively.

  8. Birth weight and perinatal mortality: A comparison of "optimal" birth weight in seven western European countries

    NARCIS (Netherlands)

    Graafmans, W.C.; Richardus, J.H.; Borsboom, G.J.J.M.; Bakketeig, L.; Langhoff-Roos, J.; Bergsjø, P.; Macfarlane, A.; Verloove-Vanhorick, P.; Mackenbach, J.; Aelvoet, W.; Alderdice, F.; Amelink, M.; Bakoula, C.; Blondel, B.; Bødker, B.; Bolumar, F.; Davidson, L.; Gissler, M.; Hartikainen, A.L.; Holt, J.; Kaminski, M.; Leidinger, J.; Lekea, V.; Lindmark, G.; Masuy-Stroobant, G.; Pal, K. van der; Penney, G.; Purificação Araújo, M. Da; Rantakallio, P.; Rebagliato, M.

    2002-01-01

    Background. Previous studies have suggested that a population's entire birth weight distribution may be shifted towards higher or lower birth weights, and that optimal birth weight may be lower in populations with a lower average birth weight. We evaluated this hypothesis for seven western European

  9. weight infants

    African Journals Online (AJOL)

    1.9 ± 0.8). (P =0.0001) and the double bags (1.6 ± 0.8) (P =0.0001) were compared with the previous single-bag system. (4.4 ± 3.5). Of concern was the large mean volume of concentrated red cells (118.5 ± 12.5 ml) wasted per transfusion with ...

  10. Analysis and comparison of safety models using average daily, average hourly, and microscopic traffic.

    Science.gov (United States)

    Wang, Ling; Abdel-Aty, Mohamed; Wang, Xuesong; Yu, Rongjie

    2018-02-01

    There have been plenty of traffic safety studies based on average daily traffic (ADT), average hourly traffic (AHT), or microscopic traffic at 5 min intervals. Nevertheless, not enough research has compared the performance of these three types of safety studies, and seldom of previous studies have intended to find whether the results of one type of study is transferable to the other two studies. First, this study built three models: a Bayesian Poisson-lognormal model to estimate the daily crash frequency using ADT, a Bayesian Poisson-lognormal model to estimate the hourly crash frequency using AHT, and a Bayesian logistic regression model for the real-time safety analysis using microscopic traffic. The model results showed that the crash contributing factors found by different models were comparable but not the same. Four variables, i.e., the logarithm of volume, the standard deviation of speed, the logarithm of segment length, and the existence of diverge segment, were positively significant in the three models. Additionally, weaving segments experienced higher daily and hourly crash frequencies than merge and basic segments. Then, each of the ADT-based, AHT-based, and real-time models was used to estimate safety conditions at different levels: daily and hourly, meanwhile, the real-time model was also used in 5 min intervals. The results uncovered that the ADT- and AHT-based safety models performed similar in predicting daily and hourly crash frequencies, and the real-time safety model was able to provide hourly crash frequency. Copyright © 2017 Elsevier Ltd. All rights reserved.

  11. Combining forecast weights: Why and how?

    Science.gov (United States)

    Yin, Yip Chee; Kok-Haur, Ng; Hock-Eam, Lim

    2012-09-01

    This paper proposes a procedure called forecast weight averaging which is a specific combination of forecast weights obtained from different methods of constructing forecast weights for the purpose of improving the accuracy of pseudo out of sample forecasting. It is found that under certain specified conditions, forecast weight averaging can lower the mean squared forecast error obtained from model averaging. In addition, we show that in a linear and homoskedastic environment, this superior predictive ability of forecast weight averaging holds true irrespective whether the coefficients are tested by t statistic or z statistic provided the significant level is within the 10% range. By theoretical proofs and simulation study, we have shown that model averaging like, variance model averaging, simple model averaging and standard error model averaging, each produces mean squared forecast error larger than that of forecast weight averaging. Finally, this result also holds true marginally when applied to business and economic empirical data sets, Gross Domestic Product (GDP growth rate), Consumer Price Index (CPI) and Average Lending Rate (ALR) of Malaysia.

  12. Averaging for solitons with nonlinearity management

    International Nuclear Information System (INIS)

    Pelinovsky, D.E.; Kevrekidis, P.G.; Frantzeskakis, D.J.

    2003-01-01

    We develop an averaging method for solitons of the nonlinear Schroedinger equation with a periodically varying nonlinearity coefficient, which is used to effectively describe solitons in Bose-Einstein condensates, in the context of the recently proposed technique of Feshbach resonance management. Using the derived local averaged equation, we study matter-wave bright and dark solitons and demonstrate a very good agreement between solutions of the averaged and full equations

  13. DSCOVR Magnetometer Level 2 One Minute Averages

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Interplanetary magnetic field observations collected from magnetometer on DSCOVR satellite - 1-minute average of Level 1 data

  14. DSCOVR Magnetometer Level 2 One Second Averages

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Interplanetary magnetic field observations collected from magnetometer on DSCOVR satellite - 1-second average of Level 1 data

  15. Spacetime averaging of exotic singularity universes

    International Nuclear Information System (INIS)

    Dabrowski, Mariusz P.

    2011-01-01

    Taking a spacetime average as a measure of the strength of singularities we show that big-rips (type I) are stronger than big-bangs. The former have infinite spacetime averages while the latter have them equal to zero. The sudden future singularities (type II) and w-singularities (type V) have finite spacetime averages. The finite scale factor (type III) singularities for some values of the parameters may have an infinite average and in that sense they may be considered stronger than big-bangs.

  16. NOAA Average Annual Salinity (3-Zone)

    Data.gov (United States)

    California Natural Resource Agency — The 3-Zone Average Annual Salinity Digital Geography is a digital spatial framework developed using geographic information system (GIS) technology. These salinity...

  17. Physics-preserving averaging scheme based on Grunwald-Letnikov formula for gas flow in fractured media

    KAUST Repository

    Amir, Sahar Z.

    2018-01-02

    The heterogeneous natures of rock fabrics, due to the existence of multi-scale fractures and geological formations, led to the deviations from unity in the flux-equations fractional-exponent magnitudes. In this paper, the resulting non-Newtonian non-Darcy fractional-derivatives flux equations are solved using physics-preserving averaging schemes that incorporates both, original and shifted, Grunwald-Letnikov (GL) approximation formulas preserving the physics, by reducing the shifting effects, while maintaining the stability of the system, by keeping one shifted expansion. The proposed way of using the GL expansions also generate symmetrical coefficient matrices that significantly reduces the discretization complexities appearing with all shifted cases from literature, and help considerably in 2D and 3D systems. Systems equations derivations and discretization details are discussed. Then, the physics-preserving averaging scheme is explained and illustrated. Finally, results are presented and reviewed. Edge-based original GL expansions are unstable as also illustrated in literatures. Shifted GL expansions are stable but add a lot of additional weights to both discretization sides affecting the physical accuracy. In comparison, the physics-preserving averaging scheme balances the physical accuracy and stability requirements leading to a more physically conservative scheme that is more stable than the original GL approximation but might be slightly less stable than the shifted GL approximations. It is a locally conservative Single-Continuum averaging scheme that applies a finite-volume viewpoint.

  18. Physics-preserving averaging scheme based on Grunwald-Letnikov formula for gas flow in fractured media

    KAUST Repository

    Amir, Sahar Z.; Sun, Shuyu

    2018-01-01

    The heterogeneous natures of rock fabrics, due to the existence of multi-scale fractures and geological formations, led to the deviations from unity in the flux-equations fractional-exponent magnitudes. In this paper, the resulting non-Newtonian non-Darcy fractional-derivatives flux equations are solved using physics-preserving averaging schemes that incorporates both, original and shifted, Grunwald-Letnikov (GL) approximation formulas preserving the physics, by reducing the shifting effects, while maintaining the stability of the system, by keeping one shifted expansion. The proposed way of using the GL expansions also generate symmetrical coefficient matrices that significantly reduces the discretization complexities appearing with all shifted cases from literature, and help considerably in 2D and 3D systems. Systems equations derivations and discretization details are discussed. Then, the physics-preserving averaging scheme is explained and illustrated. Finally, results are presented and reviewed. Edge-based original GL expansions are unstable as also illustrated in literatures. Shifted GL expansions are stable but add a lot of additional weights to both discretization sides affecting the physical accuracy. In comparison, the physics-preserving averaging scheme balances the physical accuracy and stability requirements leading to a more physically conservative scheme that is more stable than the original GL approximation but might be slightly less stable than the shifted GL approximations. It is a locally conservative Single-Continuum averaging scheme that applies a finite-volume viewpoint.

  19. Design for volume reduction

    NARCIS (Netherlands)

    Wever, R.; Boks, C.; Stevels, A.

    2007-01-01

    Traditionally packaging design-for-sustainability (DfS) strongly focuses on resource conservation and material recycling. The type and amount of materials used has been the driver in design. For consumer electronics (CE) products this weight-based approach is too limited; a volume-based approach is

  20. Improving consensus structure by eliminating averaging artifacts

    Directory of Open Access Journals (Sweden)

    KC Dukka B

    2009-03-01

    Full Text Available Abstract Background Common structural biology methods (i.e., NMR and molecular dynamics often produce ensembles of molecular structures. Consequently, averaging of 3D coordinates of molecular structures (proteins and RNA is a frequent approach to obtain a consensus structure that is representative of the ensemble. However, when the structures are averaged, artifacts can result in unrealistic local geometries, including unphysical bond lengths and angles. Results Herein, we describe a method to derive representative structures while limiting the number of artifacts. Our approach is based on a Monte Carlo simulation technique that drives a starting structure (an extended or a 'close-by' structure towards the 'averaged structure' using a harmonic pseudo energy function. To assess the performance of the algorithm, we applied our approach to Cα models of 1364 proteins generated by the TASSER structure prediction algorithm. The average RMSD of the refined model from the native structure for the set becomes worse by a mere 0.08 Å compared to the average RMSD of the averaged structures from the native structure (3.28 Å for refined structures and 3.36 A for the averaged structures. However, the percentage of atoms involved in clashes is greatly reduced (from 63% to 1%; in fact, the majority of the refined proteins had zero clashes. Moreover, a small number (38 of refined structures resulted in lower RMSD to the native protein versus the averaged structure. Finally, compared to PULCHRA 1, our approach produces representative structure of similar RMSD quality, but with much fewer clashes. Conclusion The benchmarking results demonstrate that our approach for removing averaging artifacts can be very beneficial for the structural biology community. Furthermore, the same approach can be applied to almost any problem where averaging of 3D coordinates is performed. Namely, structure averaging is also commonly performed in RNA secondary prediction 2, which

  1. 40 CFR 76.11 - Emissions averaging.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 16 2010-07-01 2010-07-01 false Emissions averaging. 76.11 Section 76.11 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) ACID RAIN NITROGEN OXIDES EMISSION REDUCTION PROGRAM § 76.11 Emissions averaging. (a) General...

  2. Determinants of College Grade Point Averages

    Science.gov (United States)

    Bailey, Paul Dean

    2012-01-01

    Chapter 2: The Role of Class Difficulty in College Grade Point Averages. Grade Point Averages (GPAs) are widely used as a measure of college students' ability. Low GPAs can remove a students from eligibility for scholarships, and even continued enrollment at a university. However, GPAs are determined not only by student ability but also by the…

  3. GRID PRICING VERSUS AVERAGE PRICING FOR SLAUGHTER CATTLE: AN EMPIRICAL ANALYSIS

    OpenAIRE

    Fausti, Scott W.; Qasmi, Bashir A.

    1999-01-01

    The paper compares weekly producer revenue under grid pricing and average dressed weight pricing methods for 2560 cattle over a period of 102 weeks. Regression analysis is applied to identify factors affecting the revenue differential.

  4. Weight control behaviors of highly successful weight loss maintainers: the Portuguese Weight Control Registry.

    Science.gov (United States)

    Santos, Inês; Vieira, Paulo N; Silva, Marlene N; Sardinha, Luís B; Teixeira, Pedro J

    2017-04-01

    To describe key behaviors reported by participants in the Portuguese Weight Control Registry and to determine associations between these behaviors and weight loss maintenance. A total of 388 adults participated in this cross-sectional study. Assessments included demographic information, weight history, weight loss and weight maintenance strategies, dietary intake, and physical activity. Participants lost on average 18 kg, which they had maintained for ~28 months. Their average dietary intake was 2199 kcal/day, with 33 % of energy coming from fat. About 78 % of participants engaged in levels of moderate-plus-vigorous physical activity exceeding 150 min/week (51 % above 250 min/week), with men accumulating 82 more minutes than women (p breakfast. Greater weight loss maintenance was associated with higher levels of physical activity, walking, weight self-monitoring, establishing specific goals, and with reduced portion size use, reduced consumption of carbohydrates, and increased consumption of protein, (p < 0.05). Results indicate that weight loss maintenance is possible through the adoption of a nutritionally-balanced diet and regular participation in physical activity, but also suggest that adopting different (and, to a degree, individualized) set of behavioral strategies is key for achieving success.

  5. Preoperative computed tomography volumetry and graft weight estimation in adult living donor liver transplantation

    Energy Technology Data Exchange (ETDEWEB)

    Pinheiro, Rafael S.; Cruz Junior, Ruy J.; Andraus, Wellington; Ducatti, Liliana; Martino, Rodrigo B.; Nacif, Lucas S.; Rocha-Santos, Vinicius; Arantes, Rubens M.; D' Albuquerque, Luiz A.C., E-mail: rsnpinheiro@gmail.com [Universidade de Sao Paulo (USP), SP (Brazil). Dept. de Gastroenterologia. Div. de Transplante de Orgaos do Aparelho Digestivo; Lai, Quirino [Universidade de L' Aquila, San Salvatore Hospital (Italy); Ibuki, Felicia S.; Rocha, Manoel S. [Universidade de Sao Paulo (USP), SP (Brazil). Departamento de Radiologia

    2017-09-01

    Background: Computed tomography volumetry (CTV) is a useful tool for predicting graft weights (GW) for living donor liver transplantation (LDLT). Few studies have examined the correlation between CTV and GW in normal liver parenchyma. Aim: To analyze the correlation between CTV and GW in an adult LDLT population and provide a systematic review of the existing mathematical models to calculate partial liver graft weight. Methods: Between January 2009 and January 2013, 28 consecutive donors undergoing right hepatectomy for LDLT were retrospectively reviewed. All grafts were perfused with HTK solution. Estimated graft volume was estimated by CTV and these values were compared to the actual graft weight, which was measured after liver harvesting and perfusion. Results: Median actual GW was 782.5 g, averaged 791.43±136 g and ranged from 520-1185 g. Median estimated graft volume was 927.5 ml, averaged 944.86±200.74 ml and ranged from 600-1477 ml. Linear regression of estimated graft volume and actual GW was significantly linear (GW=0.82 estimated graft volume, r{sup 2} =0.98, slope=0.47, standard deviation of 0.024 and p<0.0001). Spearman Linear correlation was 0.65 with 95% CI of 0.45 – 0.99 (p<0.0001). Conclusion: The one-to-one rule did not applied in patients with normal liver parenchyma. A better estimation of graft weight could be reached by multiplying estimated graft volume by 0.82. (author)

  6. Preoperative computed tomography volumetry and graft weight estimation in adult living donor liver transplantation

    International Nuclear Information System (INIS)

    Pinheiro, Rafael S.; Cruz Junior, Ruy J.; Andraus, Wellington; Ducatti, Liliana; Martino, Rodrigo B.; Nacif, Lucas S.; Rocha-Santos, Vinicius; Arantes, Rubens M.; D'Albuquerque, Luiz A.C.; Ibuki, Felicia S.; Rocha, Manoel S.

    2017-01-01

    Background: Computed tomography volumetry (CTV) is a useful tool for predicting graft weights (GW) for living donor liver transplantation (LDLT). Few studies have examined the correlation between CTV and GW in normal liver parenchyma. Aim: To analyze the correlation between CTV and GW in an adult LDLT population and provide a systematic review of the existing mathematical models to calculate partial liver graft weight. Methods: Between January 2009 and January 2013, 28 consecutive donors undergoing right hepatectomy for LDLT were retrospectively reviewed. All grafts were perfused with HTK solution. Estimated graft volume was estimated by CTV and these values were compared to the actual graft weight, which was measured after liver harvesting and perfusion. Results: Median actual GW was 782.5 g, averaged 791.43±136 g and ranged from 520-1185 g. Median estimated graft volume was 927.5 ml, averaged 944.86±200.74 ml and ranged from 600-1477 ml. Linear regression of estimated graft volume and actual GW was significantly linear (GW=0.82 estimated graft volume, r"2 =0.98, slope=0.47, standard deviation of 0.024 and p<0.0001). Spearman Linear correlation was 0.65 with 95% CI of 0.45 – 0.99 (p<0.0001). Conclusion: The one-to-one rule did not applied in patients with normal liver parenchyma. A better estimation of graft weight could be reached by multiplying estimated graft volume by 0.82. (author)

  7. PREOPERATIVE COMPUTED TOMOGRAPHY VOLUMETRY AND GRAFT WEIGHT ESTIMATION IN ADULT LIVING DONOR LIVER TRANSPLANTATION

    Science.gov (United States)

    PINHEIRO, Rafael S.; CRUZ-JR, Ruy J.; ANDRAUS, Wellington; DUCATTI, Liliana; MARTINO, Rodrigo B.; NACIF, Lucas S.; ROCHA-SANTOS, Vinicius; ARANTES, Rubens M; LAI, Quirino; IBUKI, Felicia S.; ROCHA, Manoel S.; D´ALBUQUERQUE, Luiz A. C.

    2017-01-01

    ABSTRACT Background: Computed tomography volumetry (CTV) is a useful tool for predicting graft weights (GW) for living donor liver transplantation (LDLT). Few studies have examined the correlation between CTV and GW in normal liver parenchyma. Aim: To analyze the correlation between CTV and GW in an adult LDLT population and provide a systematic review of the existing mathematical models to calculate partial liver graft weight. Methods: Between January 2009 and January 2013, 28 consecutive donors undergoing right hepatectomy for LDLT were retrospectively reviewed. All grafts were perfused with HTK solution. Estimated graft volume was estimated by CTV and these values were compared to the actual graft weight, which was measured after liver harvesting and perfusion. Results: Median actual GW was 782.5 g, averaged 791.43±136 g and ranged from 520-1185 g. Median estimated graft volume was 927.5 ml, averaged 944.86±200.74 ml and ranged from 600-1477 ml. Linear regression of estimated graft volume and actual GW was significantly linear (GW=0.82 estimated graft volume, r2=0.98, slope=0.47, standard deviation of 0.024 and p<0.0001). Spearman Linear correlation was 0.65 with 95% CI of 0.45 - 0.99 (p<0.0001). Conclusion: The one-to-one rule did not applied in patients with normal liver parenchyma. A better estimation of graft weight could be reached by multiplying estimated graft volume by 0.82. PMID:28489167

  8. Calculating ensemble averaged descriptions of protein rigidity without sampling.

    Directory of Open Access Journals (Sweden)

    Luis C González

    Full Text Available Previous works have demonstrated that protein rigidity is related to thermodynamic stability, especially under conditions that favor formation of native structure. Mechanical network rigidity properties of a single conformation are efficiently calculated using the integer body-bar Pebble Game (PG algorithm. However, thermodynamic properties require averaging over many samples from the ensemble of accessible conformations to accurately account for fluctuations in network topology. We have developed a mean field Virtual Pebble Game (VPG that represents the ensemble of networks by a single effective network. That is, all possible number of distance constraints (or bars that can form between a pair of rigid bodies is replaced by the average number. The resulting effective network is viewed as having weighted edges, where the weight of an edge quantifies its capacity to absorb degrees of freedom. The VPG is interpreted as a flow problem on this effective network, which eliminates the need to sample. Across a nonredundant dataset of 272 protein structures, we apply the VPG to proteins for the first time. Our results show numerically and visually that the rigidity characterizations of the VPG accurately reflect the ensemble averaged [Formula: see text] properties. This result positions the VPG as an efficient alternative to understand the mechanical role that chemical interactions play in maintaining protein stability.

  9. Calculating ensemble averaged descriptions of protein rigidity without sampling.

    Science.gov (United States)

    González, Luis C; Wang, Hui; Livesay, Dennis R; Jacobs, Donald J

    2012-01-01

    Previous works have demonstrated that protein rigidity is related to thermodynamic stability, especially under conditions that favor formation of native structure. Mechanical network rigidity properties of a single conformation are efficiently calculated using the integer body-bar Pebble Game (PG) algorithm. However, thermodynamic properties require averaging over many samples from the ensemble of accessible conformations to accurately account for fluctuations in network topology. We have developed a mean field Virtual Pebble Game (VPG) that represents the ensemble of networks by a single effective network. That is, all possible number of distance constraints (or bars) that can form between a pair of rigid bodies is replaced by the average number. The resulting effective network is viewed as having weighted edges, where the weight of an edge quantifies its capacity to absorb degrees of freedom. The VPG is interpreted as a flow problem on this effective network, which eliminates the need to sample. Across a nonredundant dataset of 272 protein structures, we apply the VPG to proteins for the first time. Our results show numerically and visually that the rigidity characterizations of the VPG accurately reflect the ensemble averaged [Formula: see text] properties. This result positions the VPG as an efficient alternative to understand the mechanical role that chemical interactions play in maintaining protein stability.

  10. Computation of the bounce-average code

    International Nuclear Information System (INIS)

    Cutler, T.A.; Pearlstein, L.D.; Rensink, M.E.

    1977-01-01

    The bounce-average computer code simulates the two-dimensional velocity transport of ions in a mirror machine. The code evaluates and bounce-averages the collision operator and sources along the field line. A self-consistent equilibrium magnetic field is also computed using the long-thin approximation. Optionally included are terms that maintain μ, J invariance as the magnetic field changes in time. The assumptions and analysis that form the foundation of the bounce-average code are described. When references can be cited, the required results are merely stated and explained briefly. A listing of the code is appended

  11. Multiple-level defect species evaluation from average carrier decay

    Science.gov (United States)

    Debuf, Didier

    2003-10-01

    An expression for the average decay is determined by solving the the carrier continuity equations, which include terms for multiple defect recombination. This expression is the decay measured by techniques such as the contactless photoconductance decay method, which determines the average or volume integrated decay. Implicit in the above is the requirement for good surface passivation such that only bulk properties are observed. A proposed experimental configuration is given to achieve the intended goal of an assessment of the type of defect in an n-type Czochralski-grown silicon semiconductor with an unusually high relative lifetime. The high lifetime is explained in terms of a ground excited state multiple-level defect system. Also, minority carrier trapping is investigated.

  12. Rotational averaging of multiphoton absorption cross sections

    Energy Technology Data Exchange (ETDEWEB)

    Friese, Daniel H., E-mail: daniel.h.friese@uit.no; Beerepoot, Maarten T. P.; Ruud, Kenneth [Centre for Theoretical and Computational Chemistry, University of Tromsø — The Arctic University of Norway, N-9037 Tromsø (Norway)

    2014-11-28

    Rotational averaging of tensors is a crucial step in the calculation of molecular properties in isotropic media. We present a scheme for the rotational averaging of multiphoton absorption cross sections. We extend existing literature on rotational averaging to even-rank tensors of arbitrary order and derive equations that require only the number of photons as input. In particular, we derive the first explicit expressions for the rotational average of five-, six-, and seven-photon absorption cross sections. This work is one of the required steps in making the calculation of these higher-order absorption properties possible. The results can be applied to any even-rank tensor provided linearly polarized light is used.

  13. Sea Surface Temperature Average_SST_Master

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Sea surface temperature collected via satellite imagery from http://www.esrl.noaa.gov/psd/data/gridded/data.noaa.ersst.html and averaged for each region using ArcGIS...

  14. Trajectory averaging for stochastic approximation MCMC algorithms

    KAUST Repository

    Liang, Faming

    2010-01-01

    to the stochastic approximation Monte Carlo algorithm [Liang, Liu and Carroll J. Amer. Statist. Assoc. 102 (2007) 305-320]. The application of the trajectory averaging estimator to other stochastic approximationMCMC algorithms, for example, a stochastic

  15. Should the average tax rate be marginalized?

    Czech Academy of Sciences Publication Activity Database

    Feldman, N. E.; Katuščák, Peter

    -, č. 304 (2006), s. 1-65 ISSN 1211-3298 Institutional research plan: CEZ:MSM0021620846 Keywords : tax * labor supply * average tax Subject RIV: AH - Economics http://www.cerge-ei.cz/pdf/wp/Wp304.pdf

  16. MN Temperature Average (1961-1990) - Line

    Data.gov (United States)

    Minnesota Department of Natural Resources — This data set depicts 30-year averages (1961-1990) of monthly and annual temperatures for Minnesota. Isolines and regions were created using kriging and...

  17. MN Temperature Average (1961-1990) - Polygon

    Data.gov (United States)

    Minnesota Department of Natural Resources — This data set depicts 30-year averages (1961-1990) of monthly and annual temperatures for Minnesota. Isolines and regions were created using kriging and...

  18. Nonequilibrium statistical averages and thermo field dynamics

    International Nuclear Information System (INIS)

    Marinaro, A.; Scarpetta, Q.

    1984-01-01

    An extension of thermo field dynamics is proposed, which permits the computation of nonequilibrium statistical averages. The Brownian motion of a quantum oscillator is treated as an example. In conclusion it is pointed out that the procedure proposed to computation of time-dependent statistical average gives the correct two-point Green function for the damped oscillator. A simple extension can be used to compute two-point Green functions of free particles

  19. An approximate analytical approach to resampling averages

    DEFF Research Database (Denmark)

    Malzahn, Dorthe; Opper, M.

    2004-01-01

    Using a novel reformulation, we develop a framework to compute approximate resampling data averages analytically. The method avoids multiple retraining of statistical models on the samples. Our approach uses a combination of the replica "trick" of statistical physics and the TAP approach for appr...... for approximate Bayesian inference. We demonstrate our approach on regression with Gaussian processes. A comparison with averages obtained by Monte-Carlo sampling shows that our method achieves good accuracy....

  20. Analysis of average radiation widths of neutron resonances

    International Nuclear Information System (INIS)

    Malezki, H.; Popov, A.B.; Trzeciak, K.

    1982-01-01

    On the basis of the available data on parameters of neutron resonances average values of radiation widths (GITAsub(γ)) are calculated for a wide range of nuclei in the 50 upto 250 atomic weight range. Experimental values are compared with different variants of theoretical estimates of GITAsub(γ) which are reduced to the GITAsub(γ) dependence upon atomic weight A, excitation energy U and level density parameter a as GITAsub(γ)=CAsup(α)Usup(β)asup(γ). Besides, empirical values C, α, β, γ are selected satisfying the experimental data best of all. It is determined that the use of a=kA hypothesis leads to a sufficiently better agreement between all theoretical estimates of GITAsub(γ) and experimental values. It turned out that the estimations by Weisskopf, Bondarenko-Urin or with empirically chosen parameters give an approximately similar correspondence of calculated values GITAsub(γ)sup(p) to experimental data [ru

  1. 40 CFR 80.825 - How is the refinery or importer annual average toxics value determined?

    Science.gov (United States)

    2010-07-01

    ... volume of applicable gasoline produced or imported in batch i. Ti = The toxics value of batch i. n = The number of batches of gasoline produced or imported during the averaging period. i = Individual batch of gasoline produced or imported during the averaging period. (b) The calculation specified in paragraph (a...

  2. Dairy cow disability weights.

    Science.gov (United States)

    McConnel, Craig S; McNeil, Ashleigh A; Hadrich, Joleen C; Lombard, Jason E; Garry, Franklyn B; Heller, Jane

    2017-08-01

    Over the past 175 years, data related to human disease and death have progressed to a summary measure of population health, the Disability-Adjusted Life Year (DALY). As dairies have intensified there has been no equivalent measure of the impact of disease on the productive life and well-being of animals. The development of a disease-adjusted metric requires a consistent set of disability weights that reflect the relative severity of important diseases. The objective of this study was to use an international survey of dairy authorities to derive disability weights for primary disease categories recorded on dairies. National and international dairy health and management authorities were contacted through professional organizations, dairy industry publications and conferences, and industry contacts. Estimates of minimum, most likely, and maximum disability weights were derived for 12 common dairy cow diseases. Survey participants were asked to estimate the impact of each disease on overall health and milk production. Diseases were classified from 1 (minimal adverse effects) to 10 (death). The data was modelled using BetaPERT distributions to demonstrate the variation in these dynamic disease processes, and to identify the most likely aggregated disability weights for each disease classification. A single disability weight was assigned to each disease using the average of the combined medians for the minimum, most likely, and maximum severity scores. A total of 96 respondents provided estimates of disability weights. The final disability weight values resulted in the following order from least to most severe: retained placenta, diarrhea, ketosis, metritis, mastitis, milk fever, lame (hoof only), calving trauma, left displaced abomasum, pneumonia, musculoskeletal injury (leg, hip, back), and right displaced abomasum. The peaks of the probability density functions indicated that for certain disease states such as retained placenta there was a relatively narrow range of

  3. Weighted OFDM for wireless multipath channels

    DEFF Research Database (Denmark)

    Prasad, Ramjee; Nikookar, H.

    2000-01-01

    In this paper the novel method of "weighted OFDM" is addressed. Different types of weighting factors (including Rectangular, Bartlett, Gaussian. Raised cosine, Half-sin and Shanon) are considered. The impact of weighting of OFDM on the peak-to-average power ratio (PAPR) is investigated by means...... of simulation and is compared for the above mentioned weighting factors. Results show that by weighting of the OFDM signal the PAPR reduces. Bit error performance of weighted multicarrier transmission over a multipath channel is also investigated. Results indicate that there is a trade off between PAPR...

  4. New Nordic diet versus average Danish diet

    DEFF Research Database (Denmark)

    Khakimov, Bekzod; Poulsen, Sanne Kellebjerg; Savorani, Francesco

    2016-01-01

    and 3-hydroxybutanoic acid were related to a higher weight loss, while higher concentrations of salicylic, lactic and N-aspartic acids, and 1,5-anhydro-D-sorbitol were related to a lower weight loss. Specific gender- and seasonal differences were also observed. The study strongly indicates that healthy...... metabolites reflecting specific differences in the diets, especially intake of plant foods and seafood, and in energy metabolism related to ketone bodies and gluconeogenesis, formed the predominant metabolite pattern discriminating the intervention groups. Among NND subjects higher levels of vaccenic acid...

  5. Improved averaging for non-null interferometry

    Science.gov (United States)

    Fleig, Jon F.; Murphy, Paul E.

    2013-09-01

    Arithmetic averaging of interferometric phase measurements is a well-established method for reducing the effects of time varying disturbances, such as air turbulence and vibration. Calculating a map of the standard deviation for each pixel in the average map can provide a useful estimate of its variability. However, phase maps of complex and/or high density fringe fields frequently contain defects that severely impair the effectiveness of simple phase averaging and bias the variability estimate. These defects include large or small-area phase unwrapping artifacts, large alignment components, and voids that change in number, location, or size. Inclusion of a single phase map with a large area defect into the average is usually sufficient to spoil the entire result. Small-area phase unwrapping and void defects may not render the average map metrologically useless, but they pessimistically bias the variance estimate for the overwhelming majority of the data. We present an algorithm that obtains phase average and variance estimates that are robust against both large and small-area phase defects. It identifies and rejects phase maps containing large area voids or unwrapping artifacts. It also identifies and prunes the unreliable areas of otherwise useful phase maps, and removes the effect of alignment drift from the variance estimate. The algorithm has several run-time adjustable parameters to adjust the rejection criteria for bad data. However, a single nominal setting has been effective over a wide range of conditions. This enhanced averaging algorithm can be efficiently integrated with the phase map acquisition process to minimize the number of phase samples required to approach the practical noise floor of the metrology environment.

  6. Post-model selection inference and model averaging

    Directory of Open Access Journals (Sweden)

    Georges Nguefack-Tsague

    2011-07-01

    Full Text Available Although model selection is routinely used in practice nowadays, little is known about its precise effects on any subsequent inference that is carried out. The same goes for the effects induced by the closely related technique of model averaging. This paper is concerned with the use of the same data first to select a model and then to carry out inference, in particular point estimation and point prediction. The properties of the resulting estimator, called a post-model-selection estimator (PMSE, are hard to derive. Using selection criteria such as hypothesis testing, AIC, BIC, HQ and Cp, we illustrate that, in terms of risk function, no single PMSE dominates the others. The same conclusion holds more generally for any penalised likelihood information criterion. We also compare various model averaging schemes and show that no single one dominates the others in terms of risk function. Since PMSEs can be regarded as a special case of model averaging, with 0-1 random-weights, we propose a connection between the two theories, in the frequentist approach, by taking account of the selection procedure when performing model averaging. We illustrate the point by simulating a simple linear regression model.

  7. Determination of clothing microclimate volume

    NARCIS (Netherlands)

    Daanen, Hein; Hatcher, Kent; Havenith, George

    2005-01-01

    The average air layer thickness between human skin and clothing is an important factor in heat transfer. The trapped volume between skin and clothing is an estimator for everage air layer thickness. Several techniques are available to determine trapped volume. This study investigates the reliability

  8. A comparative analysis of 9 multi-model averaging approaches in hydrological continuous streamflow simulation

    Science.gov (United States)

    Arsenault, Richard; Gatien, Philippe; Renaud, Benoit; Brissette, François; Martel, Jean-Luc

    2015-10-01

    This study aims to test whether a weighted combination of several hydrological models can simulate flows more accurately than the models taken individually. In addition, the project attempts to identify the most efficient model averaging method and the optimal number of models to include in the weighting scheme. In order to address the first objective, streamflow was simulated using four lumped hydrological models (HSAMI, HMETS, MOHYSE and GR4J-6), each of which were calibrated with three different objective functions on 429 watersheds. The resulting 12 hydrographs (4 models × 3 metrics) were weighted and combined with the help of 9 averaging methods which are the simple arithmetic mean (SAM), Akaike information criterion (AICA), Bates-Granger (BGA), Bayes information criterion (BICA), Bayesian model averaging (BMA), Granger-Ramanathan average variant A, B and C (GRA, GRB and GRC) and the average by SCE-UA optimization (SCA). The same weights were then applied to the hydrographs in validation mode, and the Nash-Sutcliffe Efficiency metric was measured between the averaged and observed hydrographs. Statistical analyses were performed to compare the accuracy of weighted methods to that of individual models. A Kruskal-Wallis test and a multi-objective optimization algorithm were then used to identify the most efficient weighted method and the optimal number of models to integrate. Results suggest that the GRA, GRB, GRC and SCA weighted methods perform better than the individual members. Model averaging from these four methods were superior to the best of the individual members in 76% of the cases. Optimal combinations on all watersheds included at least one of each of the four hydrological models. None of the optimal combinations included all members of the ensemble of 12 hydrographs. The Granger-Ramanathan average variant C (GRC) is recommended as the best compromise between accuracy, speed of execution, and simplicity.

  9. Asynchronous Gossip for Averaging and Spectral Ranking

    Science.gov (United States)

    Borkar, Vivek S.; Makhijani, Rahul; Sundaresan, Rajesh

    2014-08-01

    We consider two variants of the classical gossip algorithm. The first variant is a version of asynchronous stochastic approximation. We highlight a fundamental difficulty associated with the classical asynchronous gossip scheme, viz., that it may not converge to a desired average, and suggest an alternative scheme based on reinforcement learning that has guaranteed convergence to the desired average. We then discuss a potential application to a wireless network setting with simultaneous link activation constraints. The second variant is a gossip algorithm for distributed computation of the Perron-Frobenius eigenvector of a nonnegative matrix. While the first variant draws upon a reinforcement learning algorithm for an average cost controlled Markov decision problem, the second variant draws upon a reinforcement learning algorithm for risk-sensitive control. We then discuss potential applications of the second variant to ranking schemes, reputation networks, and principal component analysis.

  10. Benchmarking statistical averaging of spectra with HULLAC

    Science.gov (United States)

    Klapisch, Marcel; Busquet, Michel

    2008-11-01

    Knowledge of radiative properties of hot plasmas is important for ICF, astrophysics, etc When mid-Z or high-Z elements are present, the spectra are so complex that one commonly uses statistically averaged description of atomic systems [1]. In a recent experiment on Fe[2], performed under controlled conditions, high resolution transmission spectra were obtained. The new version of HULLAC [3] allows the use of the same model with different levels of details/averaging. We will take advantage of this feature to check the effect of averaging with comparison with experiment. [1] A Bar-Shalom, J Oreg, and M Klapisch, J. Quant. Spectros. Rad. Transf. 65, 43 (2000). [2] J. E. Bailey, G. A. Rochau, C. A. Iglesias et al., Phys. Rev. Lett. 99, 265002-4 (2007). [3]. M. Klapisch, M. Busquet, and A. Bar-Shalom, AIP Conference Proceedings 926, 206-15 (2007).

  11. An approach to averaging digitized plantagram curves.

    Science.gov (United States)

    Hawes, M R; Heinemeyer, R; Sovak, D; Tory, B

    1994-07-01

    The averaging of outline shapes of the human foot for the purposes of determining information concerning foot shape and dimension within the context of comfort of fit of sport shoes is approached as a mathematical problem. An outline of the human footprint is obtained by standard procedures and the curvature is traced with a Hewlett Packard Digitizer. The paper describes the determination of an alignment axis, the identification of two ray centres and the division of the total curve into two overlapping arcs. Each arc is divided by equiangular rays which intersect chords between digitized points describing the arc. The radial distance of each ray is averaged within groups of foot lengths which vary by +/- 2.25 mm (approximately equal to 1/2 shoe size). The method has been used to determine average plantar curves in a study of 1197 North American males (Hawes and Sovak 1993).

  12. Books average previous decade of economic misery.

    Science.gov (United States)

    Bentley, R Alexander; Acerbi, Alberto; Ormerod, Paul; Lampos, Vasileios

    2014-01-01

    For the 20(th) century since the Depression, we find a strong correlation between a 'literary misery index' derived from English language books and a moving average of the previous decade of the annual U.S. economic misery index, which is the sum of inflation and unemployment rates. We find a peak in the goodness of fit at 11 years for the moving average. The fit between the two misery indices holds when using different techniques to measure the literary misery index, and this fit is significantly better than other possible correlations with different emotion indices. To check the robustness of the results, we also analysed books written in German language and obtained very similar correlations with the German economic misery index. The results suggest that millions of books published every year average the authors' shared economic experiences over the past decade.

  13. Books Average Previous Decade of Economic Misery

    Science.gov (United States)

    Bentley, R. Alexander; Acerbi, Alberto; Ormerod, Paul; Lampos, Vasileios

    2014-01-01

    For the 20th century since the Depression, we find a strong correlation between a ‘literary misery index’ derived from English language books and a moving average of the previous decade of the annual U.S. economic misery index, which is the sum of inflation and unemployment rates. We find a peak in the goodness of fit at 11 years for the moving average. The fit between the two misery indices holds when using different techniques to measure the literary misery index, and this fit is significantly better than other possible correlations with different emotion indices. To check the robustness of the results, we also analysed books written in German language and obtained very similar correlations with the German economic misery index. The results suggest that millions of books published every year average the authors' shared economic experiences over the past decade. PMID:24416159

  14. Exploiting scale dependence in cosmological averaging

    International Nuclear Information System (INIS)

    Mattsson, Teppo; Ronkainen, Maria

    2008-01-01

    We study the role of scale dependence in the Buchert averaging method, using the flat Lemaitre–Tolman–Bondi model as a testing ground. Within this model, a single averaging scale gives predictions that are too coarse, but by replacing it with the distance of the objects R(z) for each redshift z, we find an O(1%) precision at z<2 in the averaged luminosity and angular diameter distances compared to their exact expressions. At low redshifts, we show the improvement for generic inhomogeneity profiles, and our numerical computations further verify it up to redshifts z∼2. At higher redshifts, the method breaks down due to its inability to capture the time evolution of the inhomogeneities. We also demonstrate that the running smoothing scale R(z) can mimic acceleration, suggesting that it could be at least as important as the backreaction in explaining dark energy as an inhomogeneity induced illusion

  15. Stochastic Averaging and Stochastic Extremum Seeking

    CERN Document Server

    Liu, Shu-Jun

    2012-01-01

    Stochastic Averaging and Stochastic Extremum Seeking develops methods of mathematical analysis inspired by the interest in reverse engineering  and analysis of bacterial  convergence by chemotaxis and to apply similar stochastic optimization techniques in other environments. The first half of the text presents significant advances in stochastic averaging theory, necessitated by the fact that existing theorems are restricted to systems with linear growth, globally exponentially stable average models, vanishing stochastic perturbations, and prevent analysis over infinite time horizon. The second half of the text introduces stochastic extremum seeking algorithms for model-free optimization of systems in real time using stochastic perturbations for estimation of their gradients. Both gradient- and Newton-based algorithms are presented, offering the user the choice between the simplicity of implementation (gradient) and the ability to achieve a known, arbitrary convergence rate (Newton). The design of algorithms...

  16. Aperture averaging in strong oceanic turbulence

    Science.gov (United States)

    Gökçe, Muhsin Caner; Baykal, Yahya

    2018-04-01

    Receiver aperture averaging technique is employed in underwater wireless optical communication (UWOC) systems to mitigate the effects of oceanic turbulence, thus to improve the system performance. The irradiance flux variance is a measure of the intensity fluctuations on a lens of the receiver aperture. Using the modified Rytov theory which uses the small-scale and large-scale spatial filters, and our previously presented expression that shows the atmospheric structure constant in terms of oceanic turbulence parameters, we evaluate the irradiance flux variance and the aperture averaging factor of a spherical wave in strong oceanic turbulence. Irradiance flux variance variations are examined versus the oceanic turbulence parameters and the receiver aperture diameter are examined in strong oceanic turbulence. Also, the effect of the receiver aperture diameter on the aperture averaging factor is presented in strong oceanic turbulence.

  17. Average: the juxtaposition of procedure and context

    Science.gov (United States)

    Watson, Jane; Chick, Helen; Callingham, Rosemary

    2014-09-01

    This paper presents recent data on the performance of 247 middle school students on questions concerning average in three contexts. Analysis includes considering levels of understanding linking definition and context, performance across contexts, the relative difficulty of tasks, and difference in performance for male and female students. The outcomes lead to a discussion of the expectations of the curriculum and its implementation, as well as assessment, in relation to students' skills in carrying out procedures and their understanding about the meaning of average in context.

  18. Average-case analysis of numerical problems

    CERN Document Server

    2000-01-01

    The average-case analysis of numerical problems is the counterpart of the more traditional worst-case approach. The analysis of average error and cost leads to new insight on numerical problems as well as to new algorithms. The book provides a survey of results that were mainly obtained during the last 10 years and also contains new results. The problems under consideration include approximation/optimal recovery and numerical integration of univariate and multivariate functions as well as zero-finding and global optimization. Background material, e.g. on reproducing kernel Hilbert spaces and random fields, is provided.

  19. Grassmann Averages for Scalable Robust PCA

    DEFF Research Database (Denmark)

    Hauberg, Søren; Feragen, Aasa; Black, Michael J.

    2014-01-01

    As the collection of large datasets becomes increasingly automated, the occurrence of outliers will increase—“big data” implies “big outliers”. While principal component analysis (PCA) is often used to reduce the size of data, and scalable solutions exist, it is well-known that outliers can...... to vectors (subspaces) or elements of vectors; we focus on the latter and use a trimmed average. The resulting Trimmed Grassmann Average (TGA) is particularly appropriate for computer vision because it is robust to pixel outliers. The algorithm has low computational complexity and minimal memory requirements...

  20. 75 FR 81533 - Antidumping Proceedings: Calculation of the Weighted Average Dumping Margin and Assessment Rate...

    Science.gov (United States)

    2010-12-28

    ... non-dumped comparisons. Several World Trade Organization (``WTO'') dispute settlement reports have... methodologies have been challenged as being inconsistent with the World Trade Organization (``WTO'') General... DEPARTMENT OF COMMERCE International Trade Administration 19 CFR Part 351 [Docket No. 101130598...

  1. Environmental effects on fruit ripening and average fruit weight for three peach cultivars

    Science.gov (United States)

    Three peach cultivars, ‘Crimson Lady’ (early), ‘Redhaven’ (mid-season) and ‘Cresthaven’ (late), were planted at twelve locations within the USA in 2009. All trees were grafted on ‘Lovell’ rootstock and came from the same nursery. Five trees of each cultivar were planted at a spacing of 6m by 5m at e...

  2. Rheological properties of poly (vinylpiyrrolidone) as a function of average molecular weight and its applications

    DEFF Research Database (Denmark)

    Marani, Debora; Sudireddy, Bhaskar Reddy; Kiebach, Ragnar

    Polyvinylpyrrolidone (PVP) is an attractive material due to its solubility in aqueous and organic solvents, excellent film forming capability, and its ability to act as a dispersant in colloidal suspensions and slurries. These characteristics of PVP have led to its use in a large variety of formu......Polyvinylpyrrolidone (PVP) is an attractive material due to its solubility in aqueous and organic solvents, excellent film forming capability, and its ability to act as a dispersant in colloidal suspensions and slurries. These characteristics of PVP have led to its use in a large variety...... of formulations for pharmaceutics, food, personal care, or coatings, paintings, and printing applications. It is also widely used as organic additive, i.e. dispersant for ceramics. Regardless of the application, the control over the polymer behavior in solution is required for an efficient optimization......, which is the inherent ability of a solute to increase the viscosity of a solvent, used in the MHS equation, has been evaluated via the dilution method. The knowledge obtained from this fundamental study on PVP behavior, has been successfully applied to different case studies....

  3. Score-driven exponentially weighted moving averages and Value-at-Risk forecasting

    NARCIS (Netherlands)

    Lucas, A.; Zhang, X.

    2016-01-01

    We present a simple methodology for modeling the time variation in volatilities and other higher-order moments using a recursive updating scheme that is similar to the familiar RiskMetrics approach. The parameters are updated using the score of the forecasting distribution, which allows the

  4. Overweight, Obesity, and Weight Loss

    Science.gov (United States)

    ... Back to section menu Healthy Weight Weight and obesity Underweight Weight, fertility, and pregnancy Weight loss and ... section Home Healthy Weight Healthy Weight Weight and obesity Underweight Weight, fertility, and pregnancy Weight loss and ...

  5. Gamut Volume Index: a color preference metric based on meta-analysis and optimized colour samples.

    Science.gov (United States)

    Liu, Qiang; Huang, Zheng; Xiao, Kaida; Pointer, Michael R; Westland, Stephen; Luo, M Ronnier

    2017-07-10

    A novel metric named Gamut Volume Index (GVI) is proposed for evaluating the colour preference of lighting. This metric is based on the absolute gamut volume of optimized colour samples. The optimal colour set of the proposed metric was obtained by optimizing the weighted average correlation between the metric predictions and the subjective ratings for 8 psychophysical studies. The performance of 20 typical colour metrics was also investigated, which included colour difference based metrics, gamut based metrics, memory based metrics as well as combined metrics. It was found that the proposed GVI outperformed the existing counterparts, especially for the conditions where correlated colour temperatures differed.

  6. Average beta measurement in EXTRAP T1

    International Nuclear Information System (INIS)

    Hedin, E.R.

    1988-12-01

    Beginning with the ideal MHD pressure balance equation, an expression for the average poloidal beta, Β Θ , is derived. A method for unobtrusively measuring the quantities used to evaluate Β Θ in Extrap T1 is described. The results if a series of measurements yielding Β Θ as a function of externally applied toroidal field are presented. (author)

  7. HIGH AVERAGE POWER OPTICAL FEL AMPLIFIERS

    International Nuclear Information System (INIS)

    2005-01-01

    Historically, the first demonstration of the optical FEL was in an amplifier configuration at Stanford University [l]. There were other notable instances of amplifying a seed laser, such as the LLNL PALADIN amplifier [2] and the BNL ATF High-Gain Harmonic Generation FEL [3]. However, for the most part FELs are operated as oscillators or self amplified spontaneous emission devices. Yet, in wavelength regimes where a conventional laser seed can be used, the FEL can be used as an amplifier. One promising application is for very high average power generation, for instance FEL's with average power of 100 kW or more. The high electron beam power, high brightness and high efficiency that can be achieved with photoinjectors and superconducting Energy Recovery Linacs (ERL) combine well with the high-gain FEL amplifier to produce unprecedented average power FELs. This combination has a number of advantages. In particular, we show that for a given FEL power, an FEL amplifier can introduce lower energy spread in the beam as compared to a traditional oscillator. This properly gives the ERL based FEL amplifier a great wall-plug to optical power efficiency advantage. The optics for an amplifier is simple and compact. In addition to the general features of the high average power FEL amplifier, we will look at a 100 kW class FEL amplifier is being designed to operate on the 0.5 ampere Energy Recovery Linac which is under construction at Brookhaven National Laboratory's Collider-Accelerator Department

  8. Bayesian Averaging is Well-Temperated

    DEFF Research Database (Denmark)

    Hansen, Lars Kai

    2000-01-01

    Bayesian predictions are stochastic just like predictions of any other inference scheme that generalize from a finite sample. While a simple variational argument shows that Bayes averaging is generalization optimal given that the prior matches the teacher parameter distribution the situation is l...

  9. Gibbs equilibrium averages and Bogolyubov measure

    International Nuclear Information System (INIS)

    Sankovich, D.P.

    2011-01-01

    Application of the functional integration methods in equilibrium statistical mechanics of quantum Bose-systems is considered. We show that Gibbs equilibrium averages of Bose-operators can be represented as path integrals over a special Gauss measure defined in the corresponding space of continuous functions. We consider some problems related to integration with respect to this measure

  10. High average-power induction linacs

    International Nuclear Information System (INIS)

    Prono, D.S.; Barrett, D.; Bowles, E.; Caporaso, G.J.; Chen, Yu-Jiuan; Clark, J.C.; Coffield, F.; Newton, M.A.; Nexsen, W.; Ravenscroft, D.; Turner, W.C.; Watson, J.A.

    1989-01-01

    Induction linear accelerators (LIAs) are inherently capable of accelerating several thousand amperes of ∼ 50-ns duration pulses to > 100 MeV. In this paper the authors report progress and status in the areas of duty factor and stray power management. These technologies are vital if LIAs are to attain high average power operation. 13 figs

  11. Function reconstruction from noisy local averages

    International Nuclear Information System (INIS)

    Chen Yu; Huang Jianguo; Han Weimin

    2008-01-01

    A regularization method is proposed for the function reconstruction from noisy local averages in any dimension. Error bounds for the approximate solution in L 2 -norm are derived. A number of numerical examples are provided to show computational performance of the method, with the regularization parameters selected by different strategies

  12. A singularity theorem based on spatial averages

    Indian Academy of Sciences (India)

    journal of. July 2007 physics pp. 31–47. A singularity theorem based on spatial ... In this paper I would like to present a result which confirms – at least partially – ... A detailed analysis of how the model fits in with the .... Further, the statement that the spatial average ...... Financial support under grants FIS2004-01626 and no.

  13. Multiphase averaging of periodic soliton equations

    International Nuclear Information System (INIS)

    Forest, M.G.

    1979-01-01

    The multiphase averaging of periodic soliton equations is considered. Particular attention is given to the periodic sine-Gordon and Korteweg-deVries (KdV) equations. The periodic sine-Gordon equation and its associated inverse spectral theory are analyzed, including a discussion of the spectral representations of exact, N-phase sine-Gordon solutions. The emphasis is on physical characteristics of the periodic waves, with a motivation from the well-known whole-line solitons. A canonical Hamiltonian approach for the modulational theory of N-phase waves is prescribed. A concrete illustration of this averaging method is provided with the periodic sine-Gordon equation; explicit averaging results are given only for the N = 1 case, laying a foundation for a more thorough treatment of the general N-phase problem. For the KdV equation, very general results are given for multiphase averaging of the N-phase waves. The single-phase results of Whitham are extended to general N phases, and more importantly, an invariant representation in terms of Abelian differentials on a Riemann surface is provided. Several consequences of this invariant representation are deduced, including strong evidence for the Hamiltonian structure of N-phase modulational equations

  14. A dynamic analysis of moving average rules

    NARCIS (Netherlands)

    Chiarella, C.; He, X.Z.; Hommes, C.H.

    2006-01-01

    The use of various moving average (MA) rules remains popular with financial market practitioners. These rules have recently become the focus of a number empirical studies, but there have been very few studies of financial market models where some agents employ technical trading rules of the type

  15. 7 CFR 1209.12 - On average.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 10 2010-01-01 2010-01-01 false On average. 1209.12 Section 1209.12 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING AGREEMENTS... CONSUMER INFORMATION ORDER Mushroom Promotion, Research, and Consumer Information Order Definitions § 1209...

  16. High average-power induction linacs

    International Nuclear Information System (INIS)

    Prono, D.S.; Barrett, D.; Bowles, E.

    1989-01-01

    Induction linear accelerators (LIAs) are inherently capable of accelerating several thousand amperes of /approximately/ 50-ns duration pulses to > 100 MeV. In this paper we report progress and status in the areas of duty factor and stray power management. These technologies are vital if LIAs are to attain high average power operation. 13 figs

  17. Average Costs versus Net Present Value

    NARCIS (Netherlands)

    E.A. van der Laan (Erwin); R.H. Teunter (Ruud)

    2000-01-01

    textabstractWhile the net present value (NPV) approach is widely accepted as the right framework for studying production and inventory control systems, average cost (AC) models are more widely used. For the well known EOQ model it can be verified that (under certain conditions) the AC approach gives

  18. Average beta-beating from random errors

    CERN Document Server

    Tomas Garcia, Rogelio; Langner, Andy Sven; Malina, Lukas; Franchi, Andrea; CERN. Geneva. ATS Department

    2018-01-01

    The impact of random errors on average β-beating is studied via analytical derivations and simulations. A systematic positive β-beating is expected from random errors quadratic with the sources or, equivalently, with the rms β-beating. However, random errors do not have a systematic effect on the tune.

  19. Reliability Estimates for Undergraduate Grade Point Average

    Science.gov (United States)

    Westrick, Paul A.

    2017-01-01

    Undergraduate grade point average (GPA) is a commonly employed measure in educational research, serving as a criterion or as a predictor depending on the research question. Over the decades, researchers have used a variety of reliability coefficients to estimate the reliability of undergraduate GPA, which suggests that there has been no consensus…

  20. Tendon surveillance requirements - average tendon force

    International Nuclear Information System (INIS)

    Fulton, J.F.

    1982-01-01

    Proposed Rev. 3 to USNRC Reg. Guide 1.35 discusses the need for comparing, for individual tendons, the measured and predicted lift-off forces. Such a comparison is intended to detect any abnormal tendon force loss which might occur. Recognizing that there are uncertainties in the prediction of tendon losses, proposed Guide 1.35.1 has allowed specific tolerances on the fundamental losses. Thus, the lift-off force acceptance criteria for individual tendons appearing in Reg. Guide 1.35, Proposed Rev. 3, is stated relative to a lower bound predicted tendon force, which is obtained using the 'plus' tolerances on the fundamental losses. There is an additional acceptance criterion for the lift-off forces which is not specifically addressed in these two Reg. Guides; however, it is included in a proposed Subsection IWX to ASME Code Section XI. This criterion is based on the overriding requirement that the magnitude of prestress in the containment structure be sufficeint to meet the minimum prestress design requirements. This design requirement can be expressed as an average tendon force for each group of vertical hoop, or dome tendons. For the purpose of comparing the actual tendon forces with the required average tendon force, the lift-off forces measured for a sample of tendons within each group can be averaged to construct the average force for the entire group. However, the individual lift-off forces must be 'corrected' (normalized) prior to obtaining the sample average. This paper derives the correction factor to be used for this purpose. (orig./RW)

  1. A Predictive Likelihood Approach to Bayesian Averaging

    Directory of Open Access Journals (Sweden)

    Tomáš Jeřábek

    2015-01-01

    Full Text Available Multivariate time series forecasting is applied in a wide range of economic activities related to regional competitiveness and is the basis of almost all macroeconomic analysis. In this paper we combine multivariate density forecasts of GDP growth, inflation and real interest rates from four various models, two type of Bayesian vector autoregression (BVAR models, a New Keynesian dynamic stochastic general equilibrium (DSGE model of small open economy and DSGE-VAR model. The performance of models is identified using historical dates including domestic economy and foreign economy, which is represented by countries of the Eurozone. Because forecast accuracy of observed models are different, the weighting scheme based on the predictive likelihood, the trace of past MSE matrix, model ranks are used to combine the models. The equal-weight scheme is used as a simple combination scheme. The results show that optimally combined densities are comparable to the best individual models.

  2. High initial tidal volumes in emergency department patients at risk for acute respiratory distress syndrome.

    Science.gov (United States)

    Allison, Michael G; Scott, Michael C; Hu, Kami M; Witting, Michael D; Winters, Michael E

    2015-04-01

    Emergency department (ED) patients are at high risk for the acute respiratory distress syndrome (ARDS). Settings only 1 mL/kg above recommended tidal volumes confers harm for these patients. The purpose of this study was to determine whether ED physicians routinely initiate mechanical ventilation with low tidal volumes in patients at risk for ARDS. We retrospectively reviewed the charts of all adult patients who were intubated in an urban, academic ED. The charts were analyzed to identify patients in whom ARDS developed within 48 hours after ED admission. Patients were eligible for inclusion if they had bilateral infiltrates on imaging, had a Pao2/Fio2 ratio less than 300 mm Hg and did not have heart failure contributing to their presentation. The tidal volumes set in the ED were then compared with the recommended tidal volume of 6 mL/kg of predicted body weight. The initial tidal volumes set in the ED were higher than recommended by an average of 80 mL (95% confidence interval, 60-110, P tidal volume ventilation setting. In an academic, tertiary hospital, newly intubated ED patients in whom ARDS developed within 48 hours after intubation were ventilated with tidal volumes that exceeded recommendations by an average of 1.5 mL/kg. Copyright © 2014 Elsevier Inc. All rights reserved.

  3. Prehospital tidal volume influences hospital tidal volume: A cohort study.

    Science.gov (United States)

    Stoltze, Andrew J; Wong, Terrence S; Harland, Karisa K; Ahmed, Azeemuddin; Fuller, Brian M; Mohr, Nicholas M

    2015-06-01

    The purposes of the study are to describe current practice of ventilation in a modern air medical system and to measure the association of ventilation strategy with subsequent ventilator care and acute respiratory distress syndrome (ARDS). Retrospective observational cohort study of intubated adult patients (n = 235) transported by a university-affiliated air medical transport service to a 711-bed tertiary academic center between July 2011 and May 2013. Low tidal volume ventilation was defined as tidal volumes less than or equal to 8 mL/kg predicted body weight. Multivariable regression was used to measure the association between prehospital tidal volume, hospital ventilation strategy, and ARDS. Most patients (57%) were ventilated solely with bag valve ventilation during transport. Mean tidal volume of mechanically ventilated patients was 8.6 mL/kg predicted body weight (SD, 0.2 mL/kg). Low tidal volume ventilation was used in 13% of patients. Patients receiving low tidal volume ventilation during air medical transport were more likely to receive low tidal volume ventilation in the emergency department (P tidal volume (P = .840). Low tidal volume ventilation was rare during air medical transport. Air transport ventilation strategy influenced subsequent ventilation but was not associated with ARDS. Copyright © 2015 Elsevier Inc. All rights reserved.

  4. Construction of average adult Japanese voxel phantoms for dose assessment

    International Nuclear Information System (INIS)

    Sato, Kaoru; Takahashi, Fumiaki; Satoh, Daiki; Endo, Akira

    2011-12-01

    The International Commission on Radiological Protection (ICRP) adopted the adult reference voxel phantoms based on the physiological and anatomical reference data of Caucasian on October, 2007. The organs and tissues of these phantoms were segmented on the basis of ICRP Publication 103. In future, the dose coefficients for internal dose and dose conversion coefficients for external dose calculated using the adult reference voxel phantoms will be widely used for the radiation protection fields. On the other hand, the body sizes and organ masses of adult Japanese are generally smaller than those of adult Caucasian. In addition, there are some cases that the anatomical characteristics such as body sizes, organ masses and postures of subjects influence the organ doses in dose assessment for medical treatments and radiation accident. Therefore, it was needed to use human phantoms with average anatomical characteristics of Japanese. The authors constructed the averaged adult Japanese male and female voxel phantoms by modifying the previously developed high-resolution adult male (JM) and female (JF) voxel phantoms. It has been modified in the following three aspects: (1) The heights and weights were agreed with the Japanese averages; (2) The masses of organs and tissues were adjusted to the Japanese averages within 10%; (3) The organs and tissues, which were newly added for evaluation of the effective dose in ICRP Publication 103, were modeled. In this study, the organ masses, distances between organs, specific absorbed fractions (SAFs) and dose conversion coefficients of these phantoms were compared with those evaluated using the ICRP adult reference voxel phantoms. This report provides valuable information on the anatomical and dosimetric characteristics of the averaged adult Japanese male and female voxel phantoms developed as reference phantoms of adult Japanese. (author)

  5. Averaging hydraulic head, pressure head, and gravitational head in subsurface hydrology, and implications for averaged fluxes, and hydraulic conductivity

    Directory of Open Access Journals (Sweden)

    G. H. de Rooij

    2009-07-01

    Full Text Available Current theories for water flow in porous media are valid for scales much smaller than those at which problem of public interest manifest themselves. This provides a drive for upscaled flow equations with their associated upscaled parameters. Upscaling is often achieved through volume averaging, but the solution to the resulting closure problem imposes severe restrictions to the flow conditions that limit the practical applicability. Here, the derivation of a closed expression of the effective hydraulic conductivity is forfeited to circumvent the closure problem. Thus, more limited but practical results can be derived. At the Representative Elementary Volume scale and larger scales, the gravitational potential and fluid pressure are treated as additive potentials. The necessary requirement that the superposition be maintained across scales is combined with conservation of energy during volume integration to establish consistent upscaling equations for the various heads. The power of these upscaling equations is demonstrated by the derivation of upscaled water content-matric head relationships and the resolution of an apparent paradox reported in the literature that is shown to have arisen from a violation of the superposition principle. Applying the upscaling procedure to Darcy's Law leads to the general definition of an upscaled hydraulic conductivity. By examining this definition in detail for porous media with different degrees of heterogeneity, a series of criteria is derived that must be satisfied for Darcy's Law to remain valid at a larger scale.

  6. Ensemble bayesian model averaging using markov chain Monte Carlo sampling

    Energy Technology Data Exchange (ETDEWEB)

    Vrugt, Jasper A [Los Alamos National Laboratory; Diks, Cees G H [NON LANL; Clark, Martyn P [NON LANL

    2008-01-01

    Bayesian model averaging (BMA) has recently been proposed as a statistical method to calibrate forecast ensembles from numerical weather models. Successful implementation of BMA however, requires accurate estimates of the weights and variances of the individual competing models in the ensemble. In their seminal paper (Raftery etal. Mon Weather Rev 133: 1155-1174, 2(05)) has recommended the Expectation-Maximization (EM) algorithm for BMA model training, even though global convergence of this algorithm cannot be guaranteed. In this paper, we compare the performance of the EM algorithm and the recently developed Differential Evolution Adaptive Metropolis (DREAM) Markov Chain Monte Carlo (MCMC) algorithm for estimating the BMA weights and variances. Simulation experiments using 48-hour ensemble data of surface temperature and multi-model stream-flow forecasts show that both methods produce similar results, and that their performance is unaffected by the length of the training data set. However, MCMC simulation with DREAM is capable of efficiently handling a wide variety of BMA predictive distributions, and provides useful information about the uncertainty associated with the estimated BMA weights and variances.

  7. Statistics on exponential averaging of periodograms

    Energy Technology Data Exchange (ETDEWEB)

    Peeters, T.T.J.M. [Netherlands Energy Research Foundation (ECN), Petten (Netherlands); Ciftcioglu, Oe. [Istanbul Technical Univ. (Turkey). Dept. of Electrical Engineering

    1994-11-01

    The algorithm of exponential averaging applied to subsequent periodograms of a stochastic process is used to estimate the power spectral density (PSD). For an independent process, assuming the periodogram estimates to be distributed according to a {chi}{sup 2} distribution with 2 degrees of freedom, the probability density function (PDF) of the PSD estimate is derived. A closed expression is obtained for the moments of the distribution. Surprisingly, the proof of this expression features some new insights into the partitions and Eulers infinite product. For large values of the time constant of the averaging process, examination of the cumulant generating function shows that the PDF approximates the Gaussian distribution. Although restrictions for the statistics are seemingly tight, simulation of a real process indicates a wider applicability of the theory. (orig.).

  8. Statistics on exponential averaging of periodograms

    International Nuclear Information System (INIS)

    Peeters, T.T.J.M.; Ciftcioglu, Oe.

    1994-11-01

    The algorithm of exponential averaging applied to subsequent periodograms of a stochastic process is used to estimate the power spectral density (PSD). For an independent process, assuming the periodogram estimates to be distributed according to a χ 2 distribution with 2 degrees of freedom, the probability density function (PDF) of the PSD estimate is derived. A closed expression is obtained for the moments of the distribution. Surprisingly, the proof of this expression features some new insights into the partitions and Eulers infinite product. For large values of the time constant of the averaging process, examination of the cumulant generating function shows that the PDF approximates the Gaussian distribution. Although restrictions for the statistics are seemingly tight, simulation of a real process indicates a wider applicability of the theory. (orig.)

  9. ANALYSIS OF THE FACTORS AFFECTING THE AVERAGE

    Directory of Open Access Journals (Sweden)

    Carmen BOGHEAN

    2013-12-01

    Full Text Available Productivity in agriculture most relevantly and concisely expresses the economic efficiency of using the factors of production. Labour productivity is affected by a considerable number of variables (including the relationship system and interdependence between factors, which differ in each economic sector and influence it, giving rise to a series of technical, economic and organizational idiosyncrasies. The purpose of this paper is to analyse the underlying factors of the average work productivity in agriculture, forestry and fishing. The analysis will take into account the data concerning the economically active population and the gross added value in agriculture, forestry and fishing in Romania during 2008-2011. The distribution of the average work productivity per factors affecting it is conducted by means of the u-substitution method.

  10. Weight Loss Surgery

    Science.gov (United States)

    Weight loss surgery helps people with extreme obesity to lose weight. It may be an option if you cannot lose weight ... obesity. There are different types of weight loss surgery. They often limit the amount of food you ...

  11. Average Transverse Momentum Quantities Approaching the Lightfront

    OpenAIRE

    Boer, Daniel

    2015-01-01

    In this contribution to Light Cone 2014, three average transverse momentum quantities are discussed: the Sivers shift, the dijet imbalance, and the $p_T$ broadening. The definitions of these quantities involve integrals over all transverse momenta that are overly sensitive to the region of large transverse momenta, which conveys little information about the transverse momentum distributions of quarks and gluons inside hadrons. TMD factorization naturally suggests alternative definitions of su...

  12. Time-averaged MSD of Brownian motion

    OpenAIRE

    Andreanov, Alexei; Grebenkov, Denis

    2012-01-01

    We study the statistical properties of the time-averaged mean-square displacements (TAMSD). This is a standard non-local quadratic functional for inferring the diffusion coefficient from an individual random trajectory of a diffusing tracer in single-particle tracking experiments. For Brownian motion, we derive an exact formula for the Laplace transform of the probability density of the TAMSD by mapping the original problem onto chains of coupled harmonic oscillators. From this formula, we de...

  13. Average configuration of the geomagnetic tail

    International Nuclear Information System (INIS)

    Fairfield, D.H.

    1979-01-01

    Over 3000 hours of Imp 6 magnetic field data obtained between 20 and 33 R/sub E/ in the geomagnetic tail have been used in a statistical study of the tail configuration. A distribution of 2.5-min averages of B/sub z/ as a function of position across the tail reveals that more flux crosses the equatorial plane near the dawn and dusk flanks (B-bar/sub z/=3.γ) than near midnight (B-bar/sub z/=1.8γ). The tail field projected in the solar magnetospheric equatorial plane deviates from the x axis due to flaring and solar wind aberration by an angle α=-0.9 Y/sub SM/-2.7, where Y/sub SM/ is in earth radii and α is in degrees. After removing these effects, the B/sub y/ component of the tail field is found to depend on interplanetary sector structure. During an 'away' sector the B/sub y/ component of the tail field is on average 0.5γ greater than that during a 'toward' sector, a result that is true in both tail lobes and is independent of location across the tail. This effect means the average field reversal between northern and southern lobes of the tail is more often 178 0 rather than the 180 0 that is generally supposed

  14. Unscrambling The "Average User" Of Habbo Hotel

    Directory of Open Access Journals (Sweden)

    Mikael Johnson

    2007-01-01

    Full Text Available The “user” is an ambiguous concept in human-computer interaction and information systems. Analyses of users as social actors, participants, or configured users delineate approaches to studying design-use relationships. Here, a developer’s reference to a figure of speech, termed the “average user,” is contrasted with design guidelines. The aim is to create an understanding about categorization practices in design through a case study about the virtual community, Habbo Hotel. A qualitative analysis highlighted not only the meaning of the “average user,” but also the work that both the developer and the category contribute to this meaning. The average user a represents the unknown, b influences the boundaries of the target user groups, c legitimizes the designer to disregard marginal user feedback, and d keeps the design space open, thus allowing for creativity. The analysis shows how design and use are intertwined and highlights the developers’ role in governing different users’ interests.

  15. Changing mortality and average cohort life expectancy

    Directory of Open Access Journals (Sweden)

    Robert Schoen

    2005-10-01

    Full Text Available Period life expectancy varies with changes in mortality, and should not be confused with the life expectancy of those alive during that period. Given past and likely future mortality changes, a recent debate has arisen on the usefulness of the period life expectancy as the leading measure of survivorship. An alternative aggregate measure of period mortality which has been seen as less sensitive to period changes, the cross-sectional average length of life (CAL has been proposed as an alternative, but has received only limited empirical or analytical examination. Here, we introduce a new measure, the average cohort life expectancy (ACLE, to provide a precise measure of the average length of life of cohorts alive at a given time. To compare the performance of ACLE with CAL and with period and cohort life expectancy, we first use population models with changing mortality. Then the four aggregate measures of mortality are calculated for England and Wales, Norway, and Switzerland for the years 1880 to 2000. CAL is found to be sensitive to past and present changes in death rates. ACLE requires the most data, but gives the best representation of the survivorship of cohorts present at a given time.

  16. Determination of the linear coefficient of thermal expansion in polymer films at the nanoscale: influence of the composition of EVA copolymers and the molecular weight of PMMA.

    Science.gov (United States)

    González-Benito, J; Castillo, E; Cruz-Caldito, J F

    2015-07-28

    Nanothermal-expansion of poly(ethylene-co-vinylacetate), EVA, and poly(methyl methacrylate), PMMA, in the form of films was measured to finally obtain linear coefficients of thermal expansion, CTEs. The simple deflection of a cantilever in an atomic force microscope, AFM, was used to monitor thermal expansions at the nanoscale. The influences of: (a) the structure of EVA in terms of its composition (vinylacetate content) and (b) the size of PMMA chains in terms of the molecular weight were studied. To carry out this, several polymer samples were used, EVA copolymers with different weight percents of the vinylacetate comonomer (12, 18, 25 and 40%) and PMMA polymers with different weight average molecular weights (33.9, 64.8, 75.600 and 360.0 kg mol(-1)). The dependencies of the vinyl acetate weight fraction of EVA and the molecular weight of PMMA on their corresponding CTEs were analyzed to finally explain them using new, intuitive and very simple models based on the rule of mixtures. In the case of EVA copolymers a simple equation considering the weighted contributions of each comonomer was enough to estimate the final CTE above the glass transition temperature. On the other hand, when the molecular weight dependence is considered the free volume concept was used as novelty. The expansion of PMMA, at least at the nanoscale, was well and easily described by the sum of the weighted contributions of the occupied and free volumes, respectively.

  17. College Freshman Stress and Weight Change: Differences by Gender

    Science.gov (United States)

    Economos, Christina D.; Hildebrandt, M. Lise; Hyatt, Raymond R.

    2008-01-01

    Objectives: To examine how stress and health-related behaviors affect freshman weight change by gender. Methods: Three hundred ninety-six freshmen completed a 40-item health behavior survey and height and weight were collected at baseline and follow-up. Results: Average weight change was 5.04 lbs for males, 5.49 lbs for females. Weight gain was…

  18. Influence of dispatching rules on average production lead time for multi-stage production systems.

    Science.gov (United States)

    Hübl, Alexander; Jodlbauer, Herbert; Altendorfer, Klaus

    2013-08-01

    In this paper the influence of different dispatching rules on the average production lead time is investigated. Two theorems based on covariance between processing time and production lead time are formulated and proved theoretically. Theorem 1 links the average production lead time to the "processing time weighted production lead time" for the multi-stage production systems analytically. The influence of different dispatching rules on average lead time, which is well known from simulation and empirical studies, can be proved theoretically in Theorem 2 for a single stage production system. A simulation study is conducted to gain more insight into the influence of dispatching rules on average production lead time in a multi-stage production system. We find that the "processing time weighted average production lead time" for a multi-stage production system is not invariant of the applied dispatching rule and can be used as a dispatching rule independent indicator for single-stage production systems.

  19. Newborn birth weight in normal pregnancy in rural Telangana

    Directory of Open Access Journals (Sweden)

    Basanta M Hota

    2017-01-01

    Conclusion: Abnormal birth weight leads to many complications, both immediate and remote. However, to predict and manage such complications, one must know the average newborn birth weight. This study is the first of its kind in rural Telangana.

  20. Average properties of bidisperse bubbly flows

    Science.gov (United States)

    Serrano-García, J. C.; Mendez-Díaz, S.; Zenit, R.

    2018-03-01

    Experiments were performed in a vertical channel to study the properties of a bubbly flow composed of two distinct bubble size species. Bubbles were produced using a capillary bank with tubes with two distinct inner diameters; the flow through each capillary size was controlled such that the amount of large or small bubbles could be controlled. Using water and water-glycerin mixtures, a wide range of Reynolds and Weber number ranges were investigated. The gas volume fraction ranged between 0.5% and 6%. The measurements of the mean bubble velocity of each species and the liquid velocity variance were obtained and contrasted with the monodisperse flows with equivalent gas volume fractions. We found that the bidispersity can induce a reduction of the mean bubble velocity of the large species; for the small size species, the bubble velocity can be increased, decreased, or remain unaffected depending of the flow conditions. The liquid velocity variance of the bidisperse flows is, in general, bound by the values of the small and large monodisperse values; interestingly, in some cases, the liquid velocity fluctuations can be larger than either monodisperse case. A simple model for the liquid agitation for bidisperse flows is proposed, with good agreement with the experimental measurements.

  1. Is Weight-Based Adjustment of Automatic Exposure Control Necessary for the Reduction of Chest CT Radiation Dose?

    Science.gov (United States)

    Prakash, Priyanka; Gilman, Matthew D.; Shepard, Jo-Anne O.; Digumarthy, Subba R.

    2010-01-01

    Objective To assess the effects of radiation dose reduction in the chest CT using a weight-based adjustment of the automatic exposure control (AEC) technique. Materials and Methods With Institutional Review Board Approval, 60 patients (mean age, 59.1 years; M:F = 35:25) and 57 weight-matched patients (mean age, 52.3 years, M:F = 25:32) were scanned using a weight-adjusted AEC and non-weight-adjusted AEC, respectively on a 64-slice multidetector CT with a 0.984:1 pitch, 0.5 second rotation time, 40 mm table feed/rotation, and 2.5 mm section thickness. Patients were categorized into 3 weight categories; 90 kg (n = 48). Patient weights, scanning parameters, CT dose index volumes (CTDIvol) and dose length product (DLP) were recorded, while effective dose (ED) was estimated. Image noise was measured in the descending thoracic aorta. Data were analyzed using a standard statistical package (SAS/STAT) (Version 9.1, SAS institute Inc, Cary, NC). Results Compared to the non-weight-adjusted AEC, the weight-adjusted AEC technique resulted in an average decrease of 29% in CTDIvol and a 27% effective dose reduction (p 91 kg weight groups, respectively, compared to 20.3, 27.9 and 32.8 mGy, with non-weight-adjusted AEC. No significant difference was observed for objective image noise between the chest CT acquired with the non-weight-adjusted (15.0 ± 3.1) and weight-adjusted (16.1 ± 5.6) AEC techniques (p > 0.05). Conclusion The results of this study suggest that AEC should be tailored according to patient weight. Without weight-based adjustment of AEC, patients are exposed to a 17 - 43% higher radiation-dose from a chest CT. PMID:20046494

  2. A core-monitoring based methodology for predictions of graphite weight loss in AGR moderator bricks

    Energy Technology Data Exchange (ETDEWEB)

    McNally, K., E-mail: kevin.mcnally@hsl.gsi.gov.uk [Health and Safety Laboratory, Harpur Hill, Buxton, Derbyshire SK17 9JN (United Kingdom); Warren, N. [Health and Safety Laboratory, Harpur Hill, Buxton, Derbyshire SK17 9JN (United Kingdom); Fahad, M.; Hall, G.; Marsden, B.J. [Nuclear Graphite Research Group, School of MACE, University of Manchester, Manchester M13 9PL (United Kingdom)

    2017-04-01

    Highlights: • A statistically-based methodology for estimating graphite density is presented. • Graphite shrinkage is accounted for using a finite element model. • Differences in weight loss forecasts were found when compared to the existing model. - Abstract: Physically based models, resolved using the finite element (FE) method are often used to model changes in dimensions and the associated stress fields of graphite moderator bricks within a reactor. These models require inputs that describe the loading conditions (temperature, fluence and weight loss ‘field variables’), and coded relationships describing the behaviour of graphite under these conditions. The weight loss field variables are calculated using a reactor chemistry/physics code FEAT DIFFUSE. In this work the authors consider an alternative data source of weight loss: that from a longitudinal dataset of density measurements made on small samples trepanned from operating reactors during statutory outages. A nonlinear mixed-effect model is presented for modelling the age and depth-related trends in density. A correction that accounts for irradiation-induced dimensional changes (axial and radial shrinkage) is subsequently applied. The authors compare weight loss forecasts made using FEAT DIFFUSE with those based on an alternative statistical model for a layer four moderator brick for the Hinkley Point B, Reactor 3. The authors compare the two approaches for the weight loss distribution through the brick with a particular focus on the interstitial keyway, and for the average (over the volume of the brick) weight loss.

  3. Ovarian volume throughout life

    DEFF Research Database (Denmark)

    Kelsey, Thomas W; Dodwell, Sarah K; Wilkinson, A Graham

    2013-01-01

    conception to 82 years of age. This model shows that 69% of the variation in ovarian volume is due to age alone. We have shown that in the average case ovarian volume rises from 0.7 mL (95% CI 0.4-1.1 mL) at 2 years of age to a peak of 7.7 mL (95% CI 6.5-9.2 mL) at 20 years of age with a subsequent decline...... to about 2.8 mL (95% CI 2.7-2.9 mL) at the menopause and smaller volumes thereafter. Our model allows us to generate normal values and ranges for ovarian volume throughout life. This is the first validated normative model of ovarian volume from conception to old age; it will be of use in the diagnosis......The measurement of ovarian volume has been shown to be a useful indirect indicator of the ovarian reserve in women of reproductive age, in the diagnosis and management of a number of disorders of puberty and adult reproductive function, and is under investigation as a screening tool for ovarian...

  4. A mass-density model can account for the size-weight illusion

    Science.gov (United States)

    Bergmann Tiest, Wouter M.; Drewing, Knut

    2018-01-01

    When judging the heaviness of two objects with equal mass, people perceive the smaller and denser of the two as being heavier. Despite the large number of theories, covering bottom-up and top-down approaches, none of them can fully account for all aspects of this size-weight illusion and thus for human heaviness perception. Here we propose a new maximum-likelihood estimation model which describes the illusion as the weighted average of two heaviness estimates with correlated noise: One estimate derived from the object’s mass, and the other from the object’s density, with estimates’ weights based on their relative reliabilities. While information about mass can directly be perceived, information about density will in some cases first have to be derived from mass and volume. However, according to our model at the crucial perceptual level, heaviness judgments will be biased by the objects’ density, not by its size. In two magnitude estimation experiments, we tested model predictions for the visual and the haptic size-weight illusion. Participants lifted objects which varied in mass and density. We additionally varied the reliability of the density estimate by varying the quality of either visual (Experiment 1) or haptic (Experiment 2) volume information. As predicted, with increasing quality of volume information, heaviness judgments were increasingly biased towards the object’s density: Objects of the same density were perceived as more similar and big objects were perceived as increasingly lighter than small (denser) objects of the same mass. This perceived difference increased with an increasing difference in density. In an additional two-alternative forced choice heaviness experiment, we replicated that the illusion strength increased with the quality of volume information (Experiment 3). Overall, the results highly corroborate our model, which seems promising as a starting point for a unifying framework for the size-weight illusion and human heaviness

  5. A mass-density model can account for the size-weight illusion.

    Science.gov (United States)

    Wolf, Christian; Bergmann Tiest, Wouter M; Drewing, Knut

    2018-01-01

    When judging the heaviness of two objects with equal mass, people perceive the smaller and denser of the two as being heavier. Despite the large number of theories, covering bottom-up and top-down approaches, none of them can fully account for all aspects of this size-weight illusion and thus for human heaviness perception. Here we propose a new maximum-likelihood estimation model which describes the illusion as the weighted average of two heaviness estimates with correlated noise: One estimate derived from the object's mass, and the other from the object's density, with estimates' weights based on their relative reliabilities. While information about mass can directly be perceived, information about density will in some cases first have to be derived from mass and volume. However, according to our model at the crucial perceptual level, heaviness judgments will be biased by the objects' density, not by its size. In two magnitude estimation experiments, we tested model predictions for the visual and the haptic size-weight illusion. Participants lifted objects which varied in mass and density. We additionally varied the reliability of the density estimate by varying the quality of either visual (Experiment 1) or haptic (Experiment 2) volume information. As predicted, with increasing quality of volume information, heaviness judgments were increasingly biased towards the object's density: Objects of the same density were perceived as more similar and big objects were perceived as increasingly lighter than small (denser) objects of the same mass. This perceived difference increased with an increasing difference in density. In an additional two-alternative forced choice heaviness experiment, we replicated that the illusion strength increased with the quality of volume information (Experiment 3). Overall, the results highly corroborate our model, which seems promising as a starting point for a unifying framework for the size-weight illusion and human heaviness perception.

  6. Modified parity space averaging approaches for online cross-calibration of redundant sensors in nuclear reactors

    Directory of Open Access Journals (Sweden)

    Moath Kassim

    2018-05-01

    Full Text Available To maintain safety and reliability of reactors, redundant sensors are usually used to measure critical variables and estimate their averaged time-dependency. Nonhealthy sensors can badly influence the estimation result of the process variable. Since online condition monitoring was introduced, the online cross-calibration method has been widely used to detect any anomaly of sensor readings among the redundant group. The cross-calibration method has four main averaging techniques: simple averaging, band averaging, weighted averaging, and parity space averaging (PSA. PSA is used to weigh redundant signals based on their error bounds and their band consistency. Using the consistency weighting factor (C, PSA assigns more weight to consistent signals that have shared bands, based on how many bands they share, and gives inconsistent signals of very low weight. In this article, three approaches are introduced for improving the PSA technique: the first is to add another consistency factor, so called trend consistency (TC, to include a consideration of the preserving of any characteristic edge that reflects the behavior of equipment/component measured by the process parameter; the second approach proposes replacing the error bound/accuracy based weighting factor (Wa with a weighting factor based on the Euclidean distance (Wd, and the third approach proposes applying Wd,TC,andC, all together. Cold neutron source data sets of four redundant hydrogen pressure transmitters from a research reactor were used to perform the validation and verification. Results showed that the second and third modified approaches lead to reasonable improvement of the PSA technique. All approaches implemented in this study were similar in that they have the capability to (1 identify and isolate a drifted sensor that should undergo calibration, (2 identify a faulty sensor/s due to long and continuous missing data range, and (3 identify a healthy sensor. Keywords: Nuclear Reactors

  7. Operator product expansion and its thermal average

    Energy Technology Data Exchange (ETDEWEB)

    Mallik, S [Saha Inst. of Nuclear Physics, Calcutta (India)

    1998-05-01

    QCD sum rules at finite temperature, like the ones at zero temperature, require the coefficients of local operators, which arise in the short distance expansion of the thermal average of two-point functions of currents. We extend the configuration space method, applied earlier at zero temperature, to the case at finite temperature. We find that, upto dimension four, two new operators arise, in addition to the two appearing already in the vacuum correlation functions. It is argued that the new operators would contribute substantially to the sum rules, when the temperature is not too low. (orig.) 7 refs.

  8. Fluctuations of wavefunctions about their classical average

    International Nuclear Information System (INIS)

    Benet, L; Flores, J; Hernandez-Saldana, H; Izrailev, F M; Leyvraz, F; Seligman, T H

    2003-01-01

    Quantum-classical correspondence for the average shape of eigenfunctions and the local spectral density of states are well-known facts. In this paper, the fluctuations of the quantum wavefunctions around the classical value are discussed. A simple random matrix model leads to a Gaussian distribution of the amplitudes whose width is determined by the classical shape of the eigenfunction. To compare this prediction with numerical calculations in chaotic models of coupled quartic oscillators, we develop a rescaling method for the components. The expectations are broadly confirmed, but deviations due to scars are observed. This effect is much reduced when both Hamiltonians have chaotic dynamics

  9. Phase-averaged transport for quasiperiodic Hamiltonians

    CERN Document Server

    Bellissard, J; Schulz-Baldes, H

    2002-01-01

    For a class of discrete quasi-periodic Schroedinger operators defined by covariant re- presentations of the rotation algebra, a lower bound on phase-averaged transport in terms of the multifractal dimensions of the density of states is proven. This result is established under a Diophantine condition on the incommensuration parameter. The relevant class of operators is distinguished by invariance with respect to symmetry automorphisms of the rotation algebra. It includes the critical Harper (almost-Mathieu) operator. As a by-product, a new solution of the frame problem associated with Weyl-Heisenberg-Gabor lattices of coherent states is given.

  10. Multistage parallel-serial time averaging filters

    International Nuclear Information System (INIS)

    Theodosiou, G.E.

    1980-01-01

    Here, a new time averaging circuit design, the 'parallel filter' is presented, which can reduce the time jitter, introduced in time measurements using counters of large dimensions. This parallel filter could be considered as a single stage unit circuit which can be repeated an arbitrary number of times in series, thus providing a parallel-serial filter type as a result. The main advantages of such a filter over a serial one are much less electronic gate jitter and time delay for the same amount of total time uncertainty reduction. (orig.)

  11. Time-averaged MSD of Brownian motion

    International Nuclear Information System (INIS)

    Andreanov, Alexei; Grebenkov, Denis S

    2012-01-01

    We study the statistical properties of the time-averaged mean-square displacements (TAMSD). This is a standard non-local quadratic functional for inferring the diffusion coefficient from an individual random trajectory of a diffusing tracer in single-particle tracking experiments. For Brownian motion, we derive an exact formula for the Laplace transform of the probability density of the TAMSD by mapping the original problem onto chains of coupled harmonic oscillators. From this formula, we deduce the first four cumulant moments of the TAMSD, the asymptotic behavior of the probability density and its accurate approximation by a generalized Gamma distribution

  12. Time-dependent angularly averaged inverse transport

    International Nuclear Information System (INIS)

    Bal, Guillaume; Jollivet, Alexandre

    2009-01-01

    This paper concerns the reconstruction of the absorption and scattering parameters in a time-dependent linear transport equation from knowledge of angularly averaged measurements performed at the boundary of a domain of interest. Such measurement settings find applications in medical and geophysical imaging. We show that the absorption coefficient and the spatial component of the scattering coefficient are uniquely determined by such measurements. We obtain stability results on the reconstruction of the absorption and scattering parameters with respect to the measured albedo operator. The stability results are obtained by a precise decomposition of the measurements into components with different singular behavior in the time domain

  13. Independence, Odd Girth, and Average Degree

    DEFF Research Database (Denmark)

    Löwenstein, Christian; Pedersen, Anders Sune; Rautenbach, Dieter

    2011-01-01

      We prove several tight lower bounds in terms of the order and the average degree for the independence number of graphs that are connected and/or satisfy some odd girth condition. Our main result is the extension of a lower bound for the independence number of triangle-free graphs of maximum...... degree at most three due to Heckman and Thomas [Discrete Math 233 (2001), 233–237] to arbitrary triangle-free graphs. For connected triangle-free graphs of order n and size m, our result implies the existence of an independent set of order at least (4n−m−1) / 7.  ...

  14. Average Nuclear properties based on statistical model

    International Nuclear Information System (INIS)

    El-Jaick, L.J.

    1974-01-01

    The rough properties of nuclei were investigated by statistical model, in systems with the same and different number of protons and neutrons, separately, considering the Coulomb energy in the last system. Some average nuclear properties were calculated based on the energy density of nuclear matter, from Weizsscker-Beth mass semiempiric formulae, generalized for compressible nuclei. In the study of a s surface energy coefficient, the great influence exercised by Coulomb energy and nuclear compressibility was verified. For a good adjust of beta stability lines and mass excess, the surface symmetry energy were established. (M.C.K.) [pt

  15. Time-averaged MSD of Brownian motion

    Science.gov (United States)

    Andreanov, Alexei; Grebenkov, Denis S.

    2012-07-01

    We study the statistical properties of the time-averaged mean-square displacements (TAMSD). This is a standard non-local quadratic functional for inferring the diffusion coefficient from an individual random trajectory of a diffusing tracer in single-particle tracking experiments. For Brownian motion, we derive an exact formula for the Laplace transform of the probability density of the TAMSD by mapping the original problem onto chains of coupled harmonic oscillators. From this formula, we deduce the first four cumulant moments of the TAMSD, the asymptotic behavior of the probability density and its accurate approximation by a generalized Gamma distribution.

  16. General expressions for the volume of organs in the MIRD-phantom and their use to arrive at an Indian ''reference'' man

    International Nuclear Information System (INIS)

    Shiv Datta

    1982-01-01

    The general expressions for the volume of body organs have been developed, when their equations are assumed to be of the same form as in the MIRD phantom. Scaling down is then carried out by introducing factors based on the average weight and height of a group of Indian adult males (workers in various units of Department of Atomic Energy, India). The general expressions for the volume of the body organs will be found handy to use when the actual data of the organs (ratios of the lengths of their axes and the volumes) become available. (author)

  17. Diet in the management of weight loss

    OpenAIRE

    Strychar, Irene

    2006-01-01

    Obesity is an established risk factor for numerous chronic diseases, and successful treatment will have an important impact on medical resources utilization, health care costs, and patient quality of life. With over 60% of our population being overweight, physicians face a major challenge in assisting patients in the process of weight loss and weight-loss maintenance. Low-calorie diets can lower total body weight by an average of 8% in the short term. These diets are well-tolerated and charac...

  18. Parents' Reactions to Finding Out That Their Children Have Average or above Average IQ Scores.

    Science.gov (United States)

    Dirks, Jean; And Others

    1983-01-01

    Parents of 41 children who had been given an individually-administered intelligence test were contacted 19 months after testing. Parents of average IQ children were less accurate in their memory of test results. Children with above average IQ experienced extremely low frequencies of sibling rivalry, conceit or pressure. (Author/HLM)

  19. Relationship between Contrast Enhancement of the Perivascular Space in the Basal Ganglia and Endolymphatic Volume Ratio.

    Science.gov (United States)

    Ohashi, Toshio; Naganawa, Shinji; Katagiri, Toshio; Kuno, Kayao

    2018-01-10

    We routinely obtain the endolymphatic hydrops (EH) image using heavily T 2 -weighted three dimensional-fluid attenuated inversion recovery (hT 2 w-3D-FLAIR) imaging at 4 hours after intravenous administration of a single-dose of gadolinium-based contrast media (IV-SD-GBCM). While repeating the examination, we speculated that the contrast enhancement of the perivascular space (PVS) in the basal ganglia might be related to the degree of EH. Therefore, the purpose of this study was to investigate the relationship between the endolymphatic volume ratio (%EL volume ) and the signal intensity of the PVS (SI-PVS). In 20 patients with a suspicion of EH, a heavily T 2 -weighted 3D-turbo spin echo sequence for MR cisternography (MRC) and an hT 2 w-3D-FLAIR as a positive perilymph image (PPI) were obtained at 4 hours after IV-SD-GBCM. The %EL volume of the cochlea and the vestibule were measured on the previously reported HYDROPS2-Mi2 image. The PVS in the basal ganglia was segmented on MRC using a region-growing method. The PVS regions were copied and pasted onto the PPI, and the SI-PVS was measured. The larger value of the right and the left ears was employed as the %EL volume , and the weighted average of both sides was employed as the SI-PVS. The correlation between the %EL volume and the SI-PVS was evaluated. There was a strong negative linear correlation between the %EL volume of the cochlea and the SI-PVS (r = -0.743, P < 0.001); however, there was no significant correlation between the %EL volume of the vestibule and the SI-PVS (r = -0.267, P = 0.256). There was a strong negative correlation between the cochlear %EL volume and the SI-PVS. Contrast enhancement of PVS might be a biomarker of EH.

  20. Trajectory averaging for stochastic approximation MCMC algorithms

    KAUST Repository

    Liang, Faming

    2010-10-01

    The subject of stochastic approximation was founded by Robbins and Monro [Ann. Math. Statist. 22 (1951) 400-407]. After five decades of continual development, it has developed into an important area in systems control and optimization, and it has also served as a prototype for the development of adaptive algorithms for on-line estimation and control of stochastic systems. Recently, it has been used in statistics with Markov chain Monte Carlo for solving maximum likelihood estimation problems and for general simulation and optimizations. In this paper, we first show that the trajectory averaging estimator is asymptotically efficient for the stochastic approximation MCMC (SAMCMC) algorithm under mild conditions, and then apply this result to the stochastic approximation Monte Carlo algorithm [Liang, Liu and Carroll J. Amer. Statist. Assoc. 102 (2007) 305-320]. The application of the trajectory averaging estimator to other stochastic approximationMCMC algorithms, for example, a stochastic approximation MLE algorithm for missing data problems, is also considered in the paper. © Institute of Mathematical Statistics, 2010.

  1. Averaged null energy condition from causality

    Science.gov (United States)

    Hartman, Thomas; Kundu, Sandipan; Tajdini, Amirhossein

    2017-07-01

    Unitary, Lorentz-invariant quantum field theories in flat spacetime obey mi-crocausality: commutators vanish at spacelike separation. For interacting theories in more than two dimensions, we show that this implies that the averaged null energy, ∫ duT uu , must be non-negative. This non-local operator appears in the operator product expansion of local operators in the lightcone limit, and therefore contributes to n-point functions. We derive a sum rule that isolates this contribution and is manifestly positive. The argument also applies to certain higher spin operators other than the stress tensor, generating an infinite family of new constraints of the form ∫ duX uuu··· u ≥ 0. These lead to new inequalities for the coupling constants of spinning operators in conformal field theory, which include as special cases (but are generally stronger than) the existing constraints from the lightcone bootstrap, deep inelastic scattering, conformal collider methods, and relative entropy. We also comment on the relation to the recent derivation of the averaged null energy condition from relative entropy, and suggest a more general connection between causality and information-theoretic inequalities in QFT.

  2. Beta-energy averaging and beta spectra

    International Nuclear Information System (INIS)

    Stamatelatos, M.G.; England, T.R.

    1976-07-01

    A simple yet highly accurate method for approximately calculating spectrum-averaged beta energies and beta spectra for radioactive nuclei is presented. This method should prove useful for users who wish to obtain accurate answers without complicated calculations of Fermi functions, complex gamma functions, and time-consuming numerical integrations as required by the more exact theoretical expressions. Therefore, this method should be a good time-saving alternative for investigators who need to make calculations involving large numbers of nuclei (e.g., fission products) as well as for occasional users interested in restricted number of nuclides. The average beta-energy values calculated by this method differ from those calculated by ''exact'' methods by no more than 1 percent for nuclides with atomic numbers in the 20 to 100 range and which emit betas of energies up to approximately 8 MeV. These include all fission products and the actinides. The beta-energy spectra calculated by the present method are also of the same quality

  3. Asymptotic Time Averages and Frequency Distributions

    Directory of Open Access Journals (Sweden)

    Muhammad El-Taha

    2016-01-01

    Full Text Available Consider an arbitrary nonnegative deterministic process (in a stochastic setting {X(t,  t≥0} is a fixed realization, i.e., sample-path of the underlying stochastic process with state space S=(-∞,∞. Using a sample-path approach, we give necessary and sufficient conditions for the long-run time average of a measurable function of process to be equal to the expectation taken with respect to the same measurable function of its long-run frequency distribution. The results are further extended to allow unrestricted parameter (time space. Examples are provided to show that our condition is not superfluous and that it is weaker than uniform integrability. The case of discrete-time processes is also considered. The relationship to previously known sufficient conditions, usually given in stochastic settings, will also be discussed. Our approach is applied to regenerative processes and an extension of a well-known result is given. For researchers interested in sample-path analysis, our results will give them the choice to work with the time average of a process or its frequency distribution function and go back and forth between the two under a mild condition.

  4. Chaotic Universe, Friedmannian on the average 2

    Energy Technology Data Exchange (ETDEWEB)

    Marochnik, L S [AN SSSR, Moscow. Inst. Kosmicheskikh Issledovanij

    1980-11-01

    The cosmological solutions are found for the equations for correlators, describing a statistically chaotic Universe, Friedmannian on the average in which delta-correlated fluctuations with amplitudes h >> 1 are excited. For the equation of state of matter p = n epsilon, the kind of solutions depends on the position of maximum of the spectrum of the metric disturbances. The expansion of the Universe, in which long-wave potential and vortical motions and gravitational waves (modes diverging at t ..-->.. 0) had been excited, tends asymptotically to the Friedmannian one at t ..-->.. identity and depends critically on n: at n < 0.26, the solution for the scalefactor is situated higher than the Friedmannian one, and lower at n > 0.26. The influence of finite at t ..-->.. 0 long-wave fluctuation modes leads to an averaged quasiisotropic solution. The contribution of quantum fluctuations and of short-wave parts of the spectrum of classical fluctuations to the expansion law is considered. Their influence is equivalent to the contribution from an ultrarelativistic gas with corresponding energy density and pressure. The restrictions are obtained for the degree of chaos (the spectrum characteristics) compatible with the observed helium abundance, which could have been retained by a completely chaotic Universe during its expansion up to the nucleosynthesis epoch.

  5. Extracting Credible Dependencies for Averaged One-Dependence Estimator Analysis

    Directory of Open Access Journals (Sweden)

    LiMin Wang

    2014-01-01

    Full Text Available Of the numerous proposals to improve the accuracy of naive Bayes (NB by weakening the conditional independence assumption, averaged one-dependence estimator (AODE demonstrates remarkable zero-one loss performance. However, indiscriminate superparent attributes will bring both considerable computational cost and negative effect on classification accuracy. In this paper, to extract the most credible dependencies we present a new type of seminaive Bayesian operation, which selects superparent attributes by building maximum weighted spanning tree and removes highly correlated children attributes by functional dependency and canonical cover analysis. Our extensive experimental comparison on UCI data sets shows that this operation efficiently identifies possible superparent attributes at training time and eliminates redundant children attributes at classification time.

  6. Mindfulness Approaches and Weight Loss, Weight Maintenance, and Weight Regain.

    Science.gov (United States)

    Dunn, Carolyn; Haubenreiser, Megan; Johnson, Madison; Nordby, Kelly; Aggarwal, Surabhi; Myer, Sarah; Thomas, Cathy

    2018-03-01

    There is an urgent need for effective weight management techniques, as more than one third of US adults are overweight or obese. Recommendations for weight loss include a combination of reducing caloric intake, increasing physical activity, and behavior modification. Behavior modification includes mindful eating or eating with awareness. The purpose of this review was to summarize the literature and examine the impact of mindful eating on weight management. The practice of mindful eating has been applied to the reduction of food cravings, portion control, body mass index, and body weight. Past reviews evaluating the relationship between mindfulness and weight management did not focus on change in mindful eating as the primary outcome or mindful eating as a measured variable. This review demonstrates strong support for inclusion of mindful eating as a component of weight management programs and may provide substantial benefit to the treatment of overweight and obesity.

  7. High average power linear induction accelerator development

    International Nuclear Information System (INIS)

    Bayless, J.R.; Adler, R.J.

    1987-07-01

    There is increasing interest in linear induction accelerators (LIAs) for applications including free electron lasers, high power microwave generators and other types of radiation sources. Lawrence Livermore National Laboratory has developed LIA technology in combination with magnetic pulse compression techniques to achieve very impressive performance levels. In this paper we will briefly discuss the LIA concept and describe our development program. Our goals are to improve the reliability and reduce the cost of LIA systems. An accelerator is presently under construction to demonstrate these improvements at an energy of 1.6 MeV in 2 kA, 65 ns beam pulses at an average beam power of approximately 30 kW. The unique features of this system are a low cost accelerator design and an SCR-switched, magnetically compressed, pulse power system. 4 refs., 7 figs

  8. FEL system with homogeneous average output

    Energy Technology Data Exchange (ETDEWEB)

    Douglas, David R.; Legg, Robert; Whitney, R. Roy; Neil, George; Powers, Thomas Joseph

    2018-01-16

    A method of varying the output of a free electron laser (FEL) on very short time scales to produce a slightly broader, but smooth, time-averaged wavelength spectrum. The method includes injecting into an accelerator a sequence of bunch trains at phase offsets from crest. Accelerating the particles to full energy to result in distinct and independently controlled, by the choice of phase offset, phase-energy correlations or chirps on each bunch train. The earlier trains will be more strongly chirped, the later trains less chirped. For an energy recovered linac (ERL), the beam may be recirculated using a transport system with linear and nonlinear momentum compactions M.sub.56, which are selected to compress all three bunch trains at the FEL with higher order terms managed.

  9. Quetelet, the average man and medical knowledge.

    Science.gov (United States)

    Caponi, Sandra

    2013-01-01

    Using two books by Adolphe Quetelet, I analyze his theory of the 'average man', which associates biological and social normality with the frequency with which certain characteristics appear in a population. The books are Sur l'homme et le développement de ses facultés and Du systeme social et des lois qui le régissent. Both reveal that Quetelet's ideas are permeated by explanatory strategies drawn from physics and astronomy, and also by discursive strategies drawn from theology and religion. The stability of the mean as opposed to the dispersion of individual characteristics and events provided the basis for the use of statistics in social sciences and medicine.

  10. [Quetelet, the average man and medical knowledge].

    Science.gov (United States)

    Caponi, Sandra

    2013-01-01

    Using two books by Adolphe Quetelet, I analyze his theory of the 'average man', which associates biological and social normality with the frequency with which certain characteristics appear in a population. The books are Sur l'homme et le développement de ses facultés and Du systeme social et des lois qui le régissent. Both reveal that Quetelet's ideas are permeated by explanatory strategies drawn from physics and astronomy, and also by discursive strategies drawn from theology and religion. The stability of the mean as opposed to the dispersion of individual characteristics and events provided the basis for the use of statistics in social sciences and medicine.

  11. Angle-averaged Compton cross sections

    International Nuclear Information System (INIS)

    Nickel, G.H.

    1983-01-01

    The scattering of a photon by an individual free electron is characterized by six quantities: α = initial photon energy in units of m 0 c 2 ; α/sub s/ = scattered photon energy in units of m 0 c 2 ; β = initial electron velocity in units of c; phi = angle between photon direction and electron direction in the laboratory frame (LF); theta = polar angle change due to Compton scattering, measured in the electron rest frame (ERF); and tau = azimuthal angle change in the ERF. We present an analytic expression for the average of the Compton cross section over phi, theta, and tau. The lowest order approximation to this equation is reasonably accurate for photons and electrons with energies of many keV

  12. Average Gait Differential Image Based Human Recognition

    Directory of Open Access Journals (Sweden)

    Jinyan Chen

    2014-01-01

    Full Text Available The difference between adjacent frames of human walking contains useful information for human gait identification. Based on the previous idea a silhouettes difference based human gait recognition method named as average gait differential image (AGDI is proposed in this paper. The AGDI is generated by the accumulation of the silhouettes difference between adjacent frames. The advantage of this method lies in that as a feature image it can preserve both the kinetic and static information of walking. Comparing to gait energy image (GEI, AGDI is more fit to representation the variation of silhouettes during walking. Two-dimensional principal component analysis (2DPCA is used to extract features from the AGDI. Experiments on CASIA dataset show that AGDI has better identification and verification performance than GEI. Comparing to PCA, 2DPCA is a more efficient and less memory storage consumption feature extraction method in gait based recognition.

  13. Reynolds averaged simulation of unsteady separated flow

    International Nuclear Information System (INIS)

    Iaccarino, G.; Ooi, A.; Durbin, P.A.; Behnia, M.

    2003-01-01

    The accuracy of Reynolds averaged Navier-Stokes (RANS) turbulence models in predicting complex flows with separation is examined. The unsteady flow around square cylinder and over a wall-mounted cube are simulated and compared with experimental data. For the cube case, none of the previously published numerical predictions obtained by steady-state RANS produced a good match with experimental data. However, evidence exists that coherent vortex shedding occurs in this flow. Its presence demands unsteady RANS computation because the flow is not statistically stationary. The present study demonstrates that unsteady RANS does indeed predict periodic shedding, and leads to much better concurrence with available experimental data than has been achieved with steady computation

  14. Angle-averaged Compton cross sections

    Energy Technology Data Exchange (ETDEWEB)

    Nickel, G.H.

    1983-01-01

    The scattering of a photon by an individual free electron is characterized by six quantities: ..cap alpha.. = initial photon energy in units of m/sub 0/c/sup 2/; ..cap alpha../sub s/ = scattered photon energy in units of m/sub 0/c/sup 2/; ..beta.. = initial electron velocity in units of c; phi = angle between photon direction and electron direction in the laboratory frame (LF); theta = polar angle change due to Compton scattering, measured in the electron rest frame (ERF); and tau = azimuthal angle change in the ERF. We present an analytic expression for the average of the Compton cross section over phi, theta, and tau. The lowest order approximation to this equation is reasonably accurate for photons and electrons with energies of many keV.

  15. The balanced survivor average causal effect.

    Science.gov (United States)

    Greene, Tom; Joffe, Marshall; Hu, Bo; Li, Liang; Boucher, Ken

    2013-05-07

    Statistical analysis of longitudinal outcomes is often complicated by the absence of observable values in patients who die prior to their scheduled measurement. In such cases, the longitudinal data are said to be "truncated by death" to emphasize that the longitudinal measurements are not simply missing, but are undefined after death. Recently, the truncation by death problem has been investigated using the framework of principal stratification to define the target estimand as the survivor average causal effect (SACE), which in the context of a two-group randomized clinical trial is the mean difference in the longitudinal outcome between the treatment and control groups for the principal stratum of always-survivors. The SACE is not identified without untestable assumptions. These assumptions have often been formulated in terms of a monotonicity constraint requiring that the treatment does not reduce survival in any patient, in conjunction with assumed values for mean differences in the longitudinal outcome between certain principal strata. In this paper, we introduce an alternative estimand, the balanced-SACE, which is defined as the average causal effect on the longitudinal outcome in a particular subset of the always-survivors that is balanced with respect to the potential survival times under the treatment and control. We propose a simple estimator of the balanced-SACE that compares the longitudinal outcomes between equivalent fractions of the longest surviving patients between the treatment and control groups and does not require a monotonicity assumption. We provide expressions for the large sample bias of the estimator, along with sensitivity analyses and strategies to minimize this bias. We consider statistical inference under a bootstrap resampling procedure.

  16. Correlation of ultrasound estimated placental volume and umbilical cord blood volume in term pregnancy.

    Science.gov (United States)

    Pannopnut, Papinwit; Kitporntheranunt, Maethaphan; Paritakul, Panwara; Kongsomboon, Kittipong

    2015-01-01

    To investigate the correlation between ultrasound measured placental volume and collected umbilical cord blood (UCB) volume in term pregnancy. An observational cross-sectional study of term singleton pregnant women in the labor ward at Maha Chakri Sirindhorn Medical Center was conducted. Placental thickness, height, and width were measured using two-dimensional (2D) ultrasound and calculated for placental volume using the volumetric mathematic model. After the delivery of the baby, UCB was collected and measured for its volume immediately. Then, birth weight, placental weight, and the actual placental volume were analyzed. The Pearson's correlation was used to determine the correlation between each two variables. A total of 35 pregnant women were eligible for the study. The mean and standard deviation of estimated placental volume and actual placental volume were 534±180 mL and 575±118 mL, respectively. The median UCB volume was 140 mL (range 98-220 mL). The UCB volume did not have a statistically significant correlation with the estimated placental volume (correlation coefficient 0.15; p=0.37). However, the UCB volume was significantly correlated with the actual placental volume (correlation coefficient 0.62; pcorrelation coefficient 0.38; p=0.02). The estimated placental volume by 2D ultrasound was not significantly correlated with the UCB volume. Further studies to establish the correlation between the UCB volume and the estimated placental volume using other types of placental imaging may be needed.

  17. 7 CFR 981.60 - Determination of kernel weight.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Determination of kernel weight. 981.60 Section 981.60... Regulating Handling Volume Regulation § 981.60 Determination of kernel weight. (a) Almonds for which settlement is made on kernel weight. All lots of almonds, whether shelled or unshelled, for which settlement...

  18. 7 CFR 981.61 - Redetermination of kernel weight.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Redetermination of kernel weight. 981.61 Section 981... GROWN IN CALIFORNIA Order Regulating Handling Volume Regulation § 981.61 Redetermination of kernel weight. The Board, on the basis of reports by handlers, shall redetermine the kernel weight of almonds...

  19. Diffusion-weighted MRI in cervical cancer

    International Nuclear Information System (INIS)

    McVeigh, Patrick Z.; Haider, Masoom A.; Syed, Aejaz M.; Milosevic, Michael; Fyles, Anthony

    2008-01-01

    The purpose was to investigate the potential value of apparent diffusion coefficient (ADC) measurement with MRI in the assessment of cervix cancer. Diffusion-weighted MRI was performed in 47 patients with cervical carcinoma undergoing chemoradiation therapy and 26 normal controls on a 1.5-T system with a b-value of 600 s/mm 2 . FIGO stage, tumor volume, nodal status, interstitial fluid pressure (IFP) and oxygen measurements were recorded. Response was defined as no visible tumor 3-6 months following completion of therapy. The average median ADC (mADC) of cervical carcinomas (1.09±0.20 x 10 -3 mm 2 /s) was significantly lower than normal cervix (2.09±0.46 x 10 -3 mm 2 /s) (P -3 mm 2 /s) compared to T2b (1.21 x 10 -3 mm 2 /s) and T3/T4 (1.10 x 10 -3 mm 2 /s) (P<0.001). In patients with squamous carcinomas the 90th percentile of ADC values was lower in responders than non-responders (P<0.05). Median ADC in cervix carcinoma is significantly lower compared to normal cervix. ADC may have predictive value in squamous tumors, but further long-term study will determine the ultimate clinical utility. (orig.)

  20. Weight Gain during Pregnancy

    Science.gov (United States)

    ... Global Map Premature Birth Report Cards Careers Archives Pregnancy Before or between pregnancies Nutrition, weight & fitness Prenatal ... fitness > Weight gain during pregnancy Weight gain during pregnancy E-mail to a friend Please fill in ...

  1. Should I Gain Weight?

    Science.gov (United States)

    ... Videos for Educators Search English Español Should I Gain Weight? KidsHealth / For Teens / Should I Gain Weight? ... something about it. Why Do People Want to Gain Weight? Some of the reasons people give for ...

  2. Determinants of weight regain after bariatric surgery.

    Science.gov (United States)

    Bastos, Emanuelle Cristina Lins; Barbosa, Emília Maria Wanderley Gusmão; Soriano, Graziele Moreira Silva; dos Santos, Ewerton Amorim; Vasconcelos, Sandra Mary Lima

    2013-01-01

    Bariatric surgery leads to an average loss of 60-75% of excess body weight with maximum weight loss in the period between 18 and 24 months postoperatively. However, several studies show that weight is regained from two years of operation. To identify the determinants of weight regain in post-bariatric surgery users. Prospective cross-sectional study with 64 patients who underwent bariatric surgery with postoperative time > 2 years valued at significant weight regain. The variables analyzed were age, sex, education, socioeconomic status, work activity related to food, time after surgery, BMI, percentage of excess weight loss, weight gain, attendance monitoring nutrition, lifestyle, eating habits, self-perception of appetite, daily use of nutritional supplements and quality of life. There were 57 (89%) women and 7 (11%) men, aged 41.76 ± 7.93 years and mean postoperative period of 53.4 ± 18.4 months. The average weight and BMI were respectively 127.48 ± 24.2 kg and 49.56 ± 6.7 kg/m2 at surgery. The minimum weight and BMI were achieved 73.0 ± 18.6 kg and 28.3 ± 5.5 kg/m2, reached in 23.7 ± 12 months postoperatively. Regained significant weight occurred in 18 (28.1%) cases. The mean postoperative period of 66 ± 8.3 months and work activities related to food showed statistical significance (p=000 and p=0.003) for the regained weight. Bariatric surgery promotes adequate reduction of excess body weight, with significant weight regain observed after five years; post-operative time and work activity related to eating out as determining factors for the occurrence of weight regain.

  3. Industrial Applications of High Average Power FELS

    CERN Document Server

    Shinn, Michelle D

    2005-01-01

    The use of lasers for material processing continues to expand, and the annual sales of such lasers exceeds $1 B (US). Large scale (many m2) processing of materials require the economical production of laser powers of the tens of kilowatts, and therefore are not yet commercial processes, although they have been demonstrated. The development of FELs based on superconducting RF (SRF) linac technology provides a scaleable path to laser outputs above 50 kW in the IR, rendering these applications economically viable, since the cost/photon drops as the output power increases. This approach also enables high average power ~ 1 kW output in the UV spectrum. Such FELs will provide quasi-cw (PRFs in the tens of MHz), of ultrafast (pulsewidth ~ 1 ps) output with very high beam quality. This talk will provide an overview of applications tests by our facility's users such as pulsed laser deposition, laser ablation, and laser surface modification, as well as present plans that will be tested with our upgraded FELs. These upg...

  4. Calculating Free Energies Using Average Force

    Science.gov (United States)

    Darve, Eric; Pohorille, Andrew; DeVincenzi, Donald L. (Technical Monitor)

    2001-01-01

    A new, general formula that connects the derivatives of the free energy along the selected, generalized coordinates of the system with the instantaneous force acting on these coordinates is derived. The instantaneous force is defined as the force acting on the coordinate of interest so that when it is subtracted from the equations of motion the acceleration along this coordinate is zero. The formula applies to simulations in which the selected coordinates are either unconstrained or constrained to fixed values. It is shown that in the latter case the formula reduces to the expression previously derived by den Otter and Briels. If simulations are carried out without constraining the coordinates of interest, the formula leads to a new method for calculating the free energy changes along these coordinates. This method is tested in two examples - rotation around the C-C bond of 1,2-dichloroethane immersed in water and transfer of fluoromethane across the water-hexane interface. The calculated free energies are compared with those obtained by two commonly used methods. One of them relies on determining the probability density function of finding the system at different values of the selected coordinate and the other requires calculating the average force at discrete locations along this coordinate in a series of constrained simulations. The free energies calculated by these three methods are in excellent agreement. The relative advantages of each method are discussed.

  5. Geographic Gossip: Efficient Averaging for Sensor Networks

    Science.gov (United States)

    Dimakis, Alexandros D. G.; Sarwate, Anand D.; Wainwright, Martin J.

    Gossip algorithms for distributed computation are attractive due to their simplicity, distributed nature, and robustness in noisy and uncertain environments. However, using standard gossip algorithms can lead to a significant waste in energy by repeatedly recirculating redundant information. For realistic sensor network model topologies like grids and random geometric graphs, the inefficiency of gossip schemes is related to the slow mixing times of random walks on the communication graph. We propose and analyze an alternative gossiping scheme that exploits geographic information. By utilizing geographic routing combined with a simple resampling method, we demonstrate substantial gains over previously proposed gossip protocols. For regular graphs such as the ring or grid, our algorithm improves standard gossip by factors of $n$ and $\\sqrt{n}$ respectively. For the more challenging case of random geometric graphs, our algorithm computes the true average to accuracy $\\epsilon$ using $O(\\frac{n^{1.5}}{\\sqrt{\\log n}} \\log \\epsilon^{-1})$ radio transmissions, which yields a $\\sqrt{\\frac{n}{\\log n}}$ factor improvement over standard gossip algorithms. We illustrate these theoretical results with experimental comparisons between our algorithm and standard methods as applied to various classes of random fields.

  6. High-average-power solid state lasers

    International Nuclear Information System (INIS)

    Summers, M.A.

    1989-01-01

    In 1987, a broad-based, aggressive R ampersand D program aimed at developing the technologies necessary to make possible the use of solid state lasers that are capable of delivering medium- to high-average power in new and demanding applications. Efforts were focused along the following major lines: development of laser and nonlinear optical materials, and of coatings for parasitic suppression and evanescent wave control; development of computational design tools; verification of computational models on thoroughly instrumented test beds; and applications of selected aspects of this technology to specific missions. In the laser materials areas, efforts were directed towards producing strong, low-loss laser glasses and large, high quality garnet crystals. The crystal program consisted of computational and experimental efforts aimed at understanding the physics, thermodynamics, and chemistry of large garnet crystal growth. The laser experimental efforts were directed at understanding thermally induced wave front aberrations in zig-zag slabs, understanding fluid mechanics, heat transfer, and optical interactions in gas-cooled slabs, and conducting critical test-bed experiments with various electro-optic switch geometries. 113 refs., 99 figs., 18 tabs

  7. The concept of average LET values determination

    International Nuclear Information System (INIS)

    Makarewicz, M.

    1981-01-01

    The concept of average LET (linear energy transfer) values determination, i.e. ordinary moments of LET in absorbed dose distribution vs. LET of ionizing radiation of any kind and any spectrum (even the unknown ones) has been presented. The method is based on measurement of ionization current with several values of voltage supplying an ionization chamber operating in conditions of columnar recombination of ions or ion recombination in clusters while the chamber is placed in the radiation field at the point of interest. By fitting a suitable algebraic expression to the measured current values one can obtain coefficients of the expression which can be interpreted as values of LET moments. One of the advantages of the method is its experimental and computational simplicity. It has been shown that for numerical estimation of certain effects dependent on LET of radiation it is not necessary to know the dose distribution but only a number of parameters of the distribution, i.e. the LET moments. (author)

  8. On spectral averages in nuclear spectroscopy

    International Nuclear Information System (INIS)

    Verbaarschot, J.J.M.

    1982-01-01

    In nuclear spectroscopy one tries to obtain a description of systems of bound nucleons. By means of theoretical models one attemps to reproduce the eigenenergies and the corresponding wave functions which then enable the computation of, for example, the electromagnetic moments and the transition amplitudes. Statistical spectroscopy can be used for studying nuclear systems in large model spaces. In this thesis, methods are developed and applied which enable the determination of quantities in a finite part of the Hilbert space, which is defined by specific quantum values. In the case of averages in a space defined by a partition of the nucleons over the single-particle orbits, the propagation coefficients reduce to Legendre interpolation polynomials. In chapter 1 these polynomials are derived with the help of a generating function and a generalization of Wick's theorem. One can then deduce the centroid and the variance of the eigenvalue distribution in a straightforward way. The results are used to calculate the systematic energy difference between states of even and odd parity for nuclei in the mass region A=10-40. In chapter 2 an efficient method for transforming fixed angular momentum projection traces into fixed angular momentum for the configuration space traces is developed. In chapter 3 it is shown that the secular behaviour can be represented by a Gaussian function of the energies. (Auth.)

  9. Perfluoroalkyl substances and changes in body weight and resting metabolic rate in response to weight-loss diets

    DEFF Research Database (Denmark)

    Liu, Gang; Dhana, Klodian; Furtado, Jeremy D

    2018-01-01

    in body weight and resting metabolic rate (RMR) in a diet-induced weight-loss setting. METHODS AND FINDINGS: In the 2-year POUNDS Lost randomized clinical trial based in Boston, Massachusetts, and Baton Rouge, Louisiana, that examined the effects of energy-restricted diets on weight changes, baseline...... and 24 months. Participants lost an average of 6.4 kg of body weight during the first 6 months (weight-loss period) and subsequently regained an average of 2.7 kg of body weight during the period of 6-24 months (weight regain period). After multivariate adjustment, baseline PFAS concentrations were...... not significantly associated with concurrent body weight or weight loss during the first 6 months. In contrast, higher baseline levels of PFASs were significantly associated with a greater weight regain, primarily in women. In women, comparing the highest to the lowest tertiles of PFAS concentrations...

  10. On the laws of thermodynamics from the escort average and on the uniqueness of statistical factors

    International Nuclear Information System (INIS)

    Yamano, Takuya

    2003-01-01

    We consider the relation between the statistical weight and the laws of thermodynamics. Our path bases on the infinitesimal perturbation from outside of the thermodynamical system. It is fair to say that the form of the first laws of thermodynamics and the Clausius' definition of thermodynamic entropy are commensurately altered once we employ the escort average of statistical weight but preserves the forms in the limit of the usual weight. We also see an example for the unique determination of the statistical factor (so-called the Gibbs theorem) in addition to the Boltzmann and the Tsallis ones

  11. Homogenization via formal multiscale asymptotics and volume averaging: How do the two techniques compare?

    KAUST Repository

    Davit, Yohan; Bell, Christopher G.; Byrne, Helen M.; Chapman, Lloyd A.C.; Kimpton, Laura S.; Lang, Georgina E.; Leonard, Katherine H.L.; Oliver, James M.; Pearson, Natalie C.; Shipley, Rebecca J.; Waters, Sarah L.; Whiteley, Jonathan P.; Wood, Brian D.; Quintard, Michel

    2013-01-01

    doing, compare their respective advantages/disadvantages from a practical point of view. This paper is also intended as a pedagogical guide and may be viewed as a tutorial for graduate students as we provide historical context, detail subtle points

  12. Using Bayes Model Averaging for Wind Power Forecasts

    Science.gov (United States)

    Preede Revheim, Pål; Beyer, Hans Georg

    2014-05-01

    For operational purposes predictions of the forecasts of the lumped output of groups of wind farms spread over larger geographic areas will often be of interest. A naive approach is to make forecasts for each individual site and sum them up to get the group forecast. It is however well documented that a better choice is to use a model that also takes advantage of spatial smoothing effects. It might however be the case that some sites tends to more accurately reflect the total output of the region, either in general or for certain wind directions. It will then be of interest giving these a greater influence over the group forecast. Bayesian model averaging (BMA) is a statistical post-processing method for producing probabilistic forecasts from ensembles. Raftery et al. [1] show how BMA can be used for statistical post processing of forecast ensembles, producing PDFs of future weather quantities. The BMA predictive PDF of a future weather quantity is a weighted average of the ensemble members' PDFs, where the weights can be interpreted as posterior probabilities and reflect the ensemble members' contribution to overall forecasting skill over a training period. In Revheim and Beyer [2] the BMA procedure used in Sloughter, Gneiting and Raftery [3] were found to produce fairly accurate PDFs for the future mean wind speed of a group of sites from the single sites wind speeds. However, when the procedure was attempted applied to wind power it resulted in either problems with the estimation of the parameters (mainly caused by longer consecutive periods of no power production) or severe underestimation (mainly caused by problems with reflecting the power curve). In this paper the problems that arose when applying BMA to wind power forecasting is met through two strategies. First, the BMA procedure is run with a combination of single site wind speeds and single site wind power production as input. This solves the problem with longer consecutive periods where the input data

  13. Compositional dependences of average positron lifetime in binary As-S/Se glasses

    International Nuclear Information System (INIS)

    Ingram, A.; Golovchak, R.; Kostrzewa, M.; Wacke, S.; Shpotyuk, M.; Shpotyuk, O.

    2012-01-01

    Compositional dependence of average positron lifetime is studied systematically in typical representatives of binary As-S and As-Se glasses. This dependence is shown to be in opposite with molar volume evolution. The origin of this anomaly is discussed in terms of bond free solid angle concept applied to different types of structurally-intrinsic nanovoids in a glass.

  14. Compositional dependences of average positron lifetime in binary As-S/Se glasses

    Energy Technology Data Exchange (ETDEWEB)

    Ingram, A. [Department of Physics of Opole University of Technology, 75 Ozimska str., Opole, PL-45370 (Poland); Golovchak, R., E-mail: roman_ya@yahoo.com [Department of Materials Science and Engineering, Lehigh University, 5 East Packer Avenue, Bethlehem, PA 18015-3195 (United States); Kostrzewa, M.; Wacke, S. [Department of Physics of Opole University of Technology, 75 Ozimska str., Opole, PL-45370 (Poland); Shpotyuk, M. [Lviv Polytechnic National University, 12, Bandery str., Lviv, UA-79013 (Ukraine); Shpotyuk, O. [Institute of Physics of Jan Dlugosz University, 13/15al. Armii Krajowej, Czestochowa, PL-42201 (Poland)

    2012-02-15

    Compositional dependence of average positron lifetime is studied systematically in typical representatives of binary As-S and As-Se glasses. This dependence is shown to be in opposite with molar volume evolution. The origin of this anomaly is discussed in terms of bond free solid angle concept applied to different types of structurally-intrinsic nanovoids in a glass.

  15. Actuator disk model of wind farms based on the rotor average wind speed

    DEFF Research Database (Denmark)

    Han, Xing Xing; Xu, Chang; Liu, De You

    2016-01-01

    Due to difficulty of estimating the reference wind speed for wake modeling in wind farm, this paper proposes a new method to calculate the momentum source based on the rotor average wind speed. The proposed model applies volume correction factor to reduce the influence of the mesh recognition of ...

  16. Longitudinal study of hippocampal volumes in heavy cannabis users.

    Science.gov (United States)

    Koenders, L; Lorenzetti, V; de Haan, L; Suo, C; Vingerhoets, Wam; van den Brink, W; Wiers, R W; Meijer, C J; Machielsen, Mwj; Goudriaan, A E; Veltman, D J; Yücel, M; Cousijn, J

    2017-08-01

    Cannabis exposure, particularly heavy cannabis use, has been associated with neuroanatomical alterations in regions rich with cannabinoid receptors such as the hippocampus in some but not in other (mainly cross-sectional) studies. However, it remains unclear whether continued heavy cannabis use alters hippocampal volume, and whether an earlier age of onset and/or a higher dosage exacerbate these changes. Twenty heavy cannabis users (mean age 21 years, range 18-24 years) and 23 matched non-cannabis using healthy controls were submitted to a comprehensive psychological assessment and magnetic resonance imaging scan at baseline and at follow-up (average of 39 months post-baseline; standard deviation=2.4). Cannabis users started smoking around 16 years and smoked on average five days per week. A novel aspect of the current study is that hippocampal volume estimates were obtained from manual tracing the hippocampus on T1-weighted anatomical magnetic resonance imaging scans, using a previously validated protocol. Compared to controls, cannabis users did not show hippocampal volume alterations at either baseline or follow-up. Hippocampal volumes increased over time in both cannabis users and controls, following similar trajectories of increase. Cannabis dose and age of onset of cannabis use did not affect hippocampal volumes. Continued heavy cannabis use did not affect hippocampal neuroanatomical changes in early adulthood. This contrasts with prior evidence on alterations in this region in samples of older adult cannabis users. In young adults using cannabis at this level, cannabis use may not be heavy enough to affect hippocampal neuroanatomy.

  17. Mechanisms of Weight Regain following Weight Loss.

    Science.gov (United States)

    Blomain, Erik Scott; Dirhan, Dara Anne; Valentino, Michael Anthony; Kim, Gilbert Won; Waldman, Scott Arthur

    2013-01-01

    Obesity is a world-wide pandemic and its incidence is on the rise along with associated comorbidities. Currently, there are few effective therapies to combat obesity. The use of lifestyle modification therapy, namely, improvements in diet and exercise, is preferable over bariatric surgery or pharmacotherapy due to surgical risks and issues with drug efficacy and safety. Although they are initially successful in producing weight loss, such lifestyle intervention strategies are generally unsuccessful in achieving long-term weight maintenance, with the vast majority of obese patients regaining their lost weight during followup. Recently, various compensatory mechanisms have been elucidated by which the body may oppose new weight loss, and this compensation may result in weight regain back to the obese baseline. The present review summarizes the available evidence on these compensatory mechanisms, with a focus on weight loss-induced changes in energy expenditure, neuroendocrine pathways, nutrient metabolism, and gut physiology. These findings have added a major focus to the field of antiobesity research. In addition to investigating pathways that induce weight loss, the present work also focuses on pathways that may instead prevent weight regain. Such strategies will be necessary for improving long-term weight loss maintenance and outcomes for patients who struggle with obesity.

  18. Weight Changes in General Practice.

    Science.gov (United States)

    Køster-Rasmussen, Rasmus

    2017-06-01

    This PhD thesis is about weight changes. What determines long-term weight changes in the adult general population? Is it possible that weight loss may not always be healthy? The present clinical guidelines for general practice advice most overweight persons and patients with type 2 diabetes to lose weight. Are the guidelines based on firm evidence?   METHODS: The back-bone of the thesis is constituted by three scientific articles based on three different population based cohort studies. Multivariable modeling and other epidemiological methods were used.   RESULTS: Article 1 examined weight changes in the general population in relation to smoking status, and proposed a graphical 'smoking cessation weight change model', demonstrating the importance of time, age and smoking status in relation to long-term weight changes. Article 2 suggested new methods to improve the processing of dietary data. It was demonstrated how median imputation for missing values and assumptions about standard portion sizes were inferior to stochastic methods conditioning on information about physiology of the individual. Article 3 evaluated the influence of prospectively planned intentional weight loss on long-term morbidity and mortality in patients with type 2 diabetes. Therapeutic intentional weight loss supervised by a medical doctor was not associated with reduced morbidity or mortality. In the general population the dietary intake of fructose and soft drinks sweetened with sugar was not associated with weight change over 9 years. Weight gain rates were large in young adults and incrementally smaller in middle aged adults. Subjects more than 60 years lost weight on average. Historical weight data suggest that the body weight increases throughout life to the age of 60-65years. A study with simulated data indicates that bias in baseline BMI may misleadingly have favored weight loss in earlier cohort studies of intentional weight loss and mortality.   DISCUSSION: The findings regarding

  19. Proven Weight Loss Methods

    Science.gov (United States)

    Fact Sheet Proven Weight Loss Methods What can weight loss do for you? Losing weight can improve your health in a number of ways. It can lower ... at www.hormone.org/Spanish . Proven Weight Loss Methods Fact Sheet www.hormone.org

  20. Average spectral efficiency analysis of FSO links over turbulence channel with adaptive transmissions and aperture averaging

    Science.gov (United States)

    Aarthi, G.; Ramachandra Reddy, G.

    2018-03-01

    In our paper, the impact of adaptive transmission schemes: (i) optimal rate adaptation (ORA) and (ii) channel inversion with fixed rate (CIFR) on the average spectral efficiency (ASE) are explored for free-space optical (FSO) communications with On-Off Keying (OOK), Polarization shift keying (POLSK), and Coherent optical wireless communication (Coherent OWC) systems under different turbulence regimes. Further to enhance the ASE we have incorporated aperture averaging effects along with the above adaptive schemes. The results indicate that ORA adaptation scheme has the advantage of improving the ASE performance compared with CIFR under moderate and strong turbulence regime. The coherent OWC system with ORA excels the other modulation schemes and could achieve ASE performance of 49.8 bits/s/Hz at the average transmitted optical power of 6 dBm under strong turbulence. By adding aperture averaging effect we could achieve an ASE of 50.5 bits/s/Hz under the same conditions. This makes ORA with Coherent OWC modulation as a favorable candidate for improving the ASE of the FSO communication system.

  1. Potential for efficient frequency conversion at high average power using solid state nonlinear optical materials

    International Nuclear Information System (INIS)

    Eimerl, D.

    1985-01-01

    High-average-power frequency conversion using solid state nonlinear materials is discussed. Recent laboratory experience and new developments in design concepts show that current technology, a few tens of watts, may be extended by several orders of magnitude. For example, using KD*P, efficient doubling (>70%) of Nd:YAG at average powers approaching 100 KW is possible; and for doubling to the blue or ultraviolet regions, the average power may approach 1 MW. Configurations using segmented apertures permit essentially unlimited scaling of average power. High average power is achieved by configuring the nonlinear material as a set of thin plates with a large ratio of surface area to volume and by cooling the exposed surfaces with a flowing gas. The design and material fabrication of such a harmonic generator are well within current technology

  2. Weight Changes following the Diagnosis of Type 2 Diabetes

    DEFF Research Database (Denmark)

    Olivarius, Niels de Fine; Siersma, Volkert Dirk; Køster-Rasmussen, Rasmus

    2015-01-01

    Aims: The association between recent and more distant weight changes before and after the diagnosis of type 2 diabetes has been little researched. The aim of this study is to determine the influence of patients’ weight history before diabetes diagnosis on the observed 6-year weight changes after...... diagnosis. Methods: A clinical cohort study combined with self-reported past weight history. In total 885 patients aged ≥40 years and newly diagnosed with clinical type 2 diabetes were included. Body weight was measured immediately after diabetes diagnosis and again at the 6-year follow up examination...... weight change after diagnosis. Conclusions: During the first on average 5.7 years after diagnosis of type 2 diabetes, patients generally follow a course of declining average weight, and these weight developments are related primarily to recent weight changes, body mass index, and age, but not to the more...

  3. Time series analysis of brain regional volume by MR image

    International Nuclear Information System (INIS)

    Tanaka, Mika; Tarusawa, Ayaka; Nihei, Mitsuyo; Fukami, Tadanori; Yuasa, Tetsuya; Wu, Jin; Ishiwata, Kiichi; Ishii, Kenji

    2010-01-01

    The present study proposed a methodology of time series analysis of volumes of frontal, parietal, temporal and occipital lobes and cerebellum because such volumetric reports along the process of individual's aging have been scarcely presented. Subjects analyzed were brain images of 2 healthy males and 18 females of av. age of 69.0 y, of which T1-weighted 3D SPGR (spoiled gradient recalled in the steady state) acquisitions with a GE SIGNA EXCITE HD 1.5T machine were conducted for 4 times in the time series of 42-50 months. The image size was 256 x 256 x (86-124) voxels with digitization level 16 bits. As the template for the regions, the standard gray matter atlas (icbn452 a tlas p robability g ray) and its labeled one (icbn.Labels), provided by UCLA Laboratory of Neuro Imaging, were used for individual's standardization. Segmentation, normalization and coregistration were performed with the MR imaging software SPM8 (Statistic Parametric Mapping 8). Volumes of regions were calculated as their voxel ratio to the whole brain voxel in percent. It was found that the regional volumes decreased with aging in all above lobes examined and cerebellum in average percent per year of -0.11, -0.07, -0.04, -0.02, and -0.03, respectively. The procedure for calculation of the regional volumes, which has been manually operated hitherto, can be automatically conducted for the individual brain using the standard atlases above. (T.T.)

  4. Intralesional and metastatic heterogeneity in malignant melanomas demonstrated by stereologic estimates of nuclear volume

    DEFF Research Database (Denmark)

    Sørensen, Flemming Brandt; Erlandsen, M

    1990-01-01

    Regional variability of nuclear 3-dimensional size can be estimated objectively using point-sampled intercepts obtained from different, defined zones within individual neoplasms. In the present study, stereologic estimates of the volume-weighted mean nuclear volume, nuclear vv, within peripheral...... on average larger in the peripheral zones of primary melanomas, than nuclear vv in central zones (2p = 6.7 x 10(-4), whereas no zonal differences were demonstrated in metastatic lesions (2p = 0.21). A marked intraindividual variation was demonstrated between primary and corresponding secondary melanomas (2p...... melanomas showed large interindividual variation. This finding emphasizes that unbiased estimates of nuclear vv are robust to regional heterogeneity of nuclear volume and thus suitable for purposes of objective, quantitative malignancy grading of melanomas....

  5. 16 CFR 500.25 - Net quantity, average quantity, permitted variations.

    Science.gov (United States)

    2010-01-01

    ... good distribution practice and which unavoidably result in change of weight or mass or measure. (c... good packaging practice: Provided, that such variations shall not be permitted to such extent that the... 16 Commercial Practices 1 2010-01-01 2010-01-01 false Net quantity, average quantity, permitted...

  6. The predictive validity of grade point average scores in a partial lottery medical school admission system

    NARCIS (Netherlands)

    Cohen-Schotanus, Janke; Muijtjens, Arno M. M.; Reinders, Jan J.; Agsteribbe, Jessica; van Rossum, Herman J. M.; van der Vleuten, Cees P. M.

    2006-01-01

    PURPOSE To ascertain whether the grade point average (GPA) of school-leaving examinations is related to study success, career development and scientific performance. The problem of restriction of range was expected to be partially reduced due to the use of a national lottery system weighted in

  7. Alternative Estimates of the Reliability of College Grade Point Averages. Professional File. Article 130, Spring 2013

    Science.gov (United States)

    Saupe, Joe L.; Eimers, Mardy T.

    2013-01-01

    The purpose of this paper is to explore differences in the reliabilities of cumulative college grade point averages (GPAs), estimated for unweighted and weighted, one-semester, 1-year, 2-year, and 4-year GPAs. Using cumulative GPAs for a freshman class at a major university, we estimate internal consistency (coefficient alpha) reliabilities for…

  8. Automatic assessment of average diaphragm motion trajectory from 4DCT images through machine learning.

    Science.gov (United States)

    Li, Guang; Wei, Jie; Huang, Hailiang; Gaebler, Carl Philipp; Yuan, Amy; Deasy, Joseph O

    2015-12-01

    To automatically estimate average diaphragm motion trajectory (ADMT) based on four-dimensional computed tomography (4DCT), facilitating clinical assessment of respiratory motion and motion variation and retrospective motion study. We have developed an effective motion extraction approach and a machine-learning-based algorithm to estimate the ADMT. Eleven patients with 22 sets of 4DCT images (4DCT1 at simulation and 4DCT2 at treatment) were studied. After automatically segmenting the lungs, the differential volume-per-slice (dVPS) curves of the left and right lungs were calculated as a function of slice number for each phase with respective to the full-exhalation. After 5-slice moving average was performed, the discrete cosine transform (DCT) was applied to analyze the dVPS curves in frequency domain. The dimensionality of the spectrum data was reduced by using several lowest frequency coefficients ( f v ) to account for most of the spectrum energy (Σ f v 2 ). Multiple linear regression (MLR) method was then applied to determine the weights of these frequencies by fitting the ground truth-the measured ADMT, which are represented by three pivot points of the diaphragm on each side. The 'leave-one-out' cross validation method was employed to analyze the statistical performance of the prediction results in three image sets: 4DCT1, 4DCT2, and 4DCT1 + 4DCT2. Seven lowest frequencies in DCT domain were found to be sufficient to approximate the patient dVPS curves ( R = 91%-96% in MLR fitting). The mean error in the predicted ADMT using leave-one-out method was 0.3 ± 1.9 mm for the left-side diaphragm and 0.0 ± 1.4 mm for the right-side diaphragm. The prediction error is lower in 4DCT2 than 4DCT1, and is the lowest in 4DCT1 and 4DCT2 combined. This frequency-analysis-based machine learning technique was employed to predict the ADMT automatically with an acceptable error (0.2 ± 1.6 mm). This volumetric approach is not affected by the presence of the lung tumors

  9. To quantum averages through asymptotic expansion of classical averages on infinite-dimensional space

    International Nuclear Information System (INIS)

    Khrennikov, Andrei

    2007-01-01

    We study asymptotic expansions of Gaussian integrals of analytic functionals on infinite-dimensional spaces (Hilbert and nuclear Frechet). We obtain an asymptotic equality coupling the Gaussian integral and the trace of the composition of scaling of the covariation operator of a Gaussian measure and the second (Frechet) derivative of a functional. In this way we couple classical average (given by an infinite-dimensional Gaussian integral) and quantum average (given by the von Neumann trace formula). We can interpret this mathematical construction as a procedure of 'dequantization' of quantum mechanics. We represent quantum mechanics as an asymptotic projection of classical statistical mechanics with infinite-dimensional phase space. This space can be represented as the space of classical fields, so quantum mechanics is represented as a projection of 'prequantum classical statistical field theory'

  10. Determining average path length and average trapping time on generalized dual dendrimer

    Science.gov (United States)

    Li, Ling; Guan, Jihong

    2015-03-01

    Dendrimer has wide number of important applications in various fields. In some cases during transport or diffusion process, it transforms into its dual structure named Husimi cactus. In this paper, we study the structure properties and trapping problem on a family of generalized dual dendrimer with arbitrary coordination numbers. We first calculate exactly the average path length (APL) of the networks. The APL increases logarithmically with the network size, indicating that the networks exhibit a small-world effect. Then we determine the average trapping time (ATT) of the trapping process in two cases, i.e., the trap placed on a central node and the trap is uniformly distributed in all the nodes of the network. In both case, we obtain explicit solutions of ATT and show how they vary with the networks size. Besides, we also discuss the influence of the coordination number on trapping efficiency.

  11. Potential of high-average-power solid state lasers

    International Nuclear Information System (INIS)

    Emmett, J.L.; Krupke, W.F.; Sooy, W.R.

    1984-01-01

    We discuss the possibility of extending solid state laser technology to high average power and of improving the efficiency of such lasers sufficiently to make them reasonable candidates for a number of demanding applications. A variety of new design concepts, materials, and techniques have emerged over the past decade that, collectively, suggest that the traditional technical limitations on power (a few hundred watts or less) and efficiency (less than 1%) can be removed. The core idea is configuring the laser medium in relatively thin, large-area plates, rather than using the traditional low-aspect-ratio rods or blocks. This presents a large surface area for cooling, and assures that deposited heat is relatively close to a cooled surface. It also minimizes the laser volume distorted by edge effects. The feasibility of such configurations is supported by recent developments in materials, fabrication processes, and optical pumps. Two types of lasers can, in principle, utilize this sheet-like gain configuration in such a way that phase and gain profiles are uniformly sampled and, to first order, yield high-quality (undistorted) beams. The zig-zag laser does this with a single plate, and should be capable of power levels up to several kilowatts. The disk laser is designed around a large number of plates, and should be capable of scaling to arbitrarily high power levels

  12. Depression, posttraumatic stress disorder, and grade point average among student servicemembers and veterans.

    Science.gov (United States)

    Bryan, Craig J; Bryan, AnnaBelle O; Hinkson, Kent; Bichrest, Michael; Ahern, D Aaron

    2014-01-01

    The current study examined relationships among self-reported depression severity, posttraumatic stress disorder (PTSD) symptom severity, and grade point average (GPA) among student servicemembers and veterans. We asked 422 student servicemembers and veterans (72% male, 86% Caucasian, mean age = 36.29 yr) to complete an anonymous online survey that assessed self-reported GPA, depression severity, PTSD severity, and frequency of academic problems (late assignments, low grades, failed exams, and skipped classes). Female respondents reported a slightly higher GPA than males (3.56 vs 3.41, respectively, p = 0.01). Depression symptoms (beta weight = -0.174, p = 0.03), male sex (beta weight = 0.160, p = 0.01), and younger age (beta weight = 0.155, p = 0.01) were associated with lower GPA but not PTSD symptoms (beta weight = -0.040, p = 0.62), although the interaction of depression and PTSD symptoms showed a nonsignificant inverse relationship with GPA (beta weight = -0.378, p = 0.08). More severe depression was associated with turning in assignments late (beta weight = 0.171, p = 0.03), failed exams (beta weight = 0.188, p = 0.02), and skipped classes (beta weight = 0.254, p = 0.01). The relationship of depression with self-reported GPA was mediated by frequency of failed examns. Results suggest that student servicemembers and veterans with greater emotional distress also report worse academic performance.

  13. Growth and relationship of live weight to body measurements in semi-domesticated reindeer (Rangifer tarandus tarandus L.

    Directory of Open Access Journals (Sweden)

    Mauri Nieminen

    1990-09-01

    Full Text Available Estimation of live weight from measurements of body dimensions is useful in many management activities with domestic animals. In present study live weight was measured from 2932 female and 1037 male semi-domesticated reindeer (Rangifer tarandus tarandus L. during different seasons in 1969-85. The age of reindeer varied between 1 day and 14 yrs. Back length (along back from second spinous process to base of tail and chest girth (just behind front legs were taken also from 1490 female and 510 male reindeer. The growth of reindeer from birth to adulthood was cumulative consisting of a rapid weight accretion during summers followed by a weight loss or stasis during winters. The mathematical analyses of the growth based on exponential solutions gave average values for growth of female and male reindeer. Body weight of females increased until the age of 4.5 yrs and that of males until the age of 5.5 yrs. During winter and spring body weight of hinds decreased 10 to 15 kg and that of stags 30 to 50 kg in different age groups. Significant linear regressions were found between live weight and back length (r = 0.809 and 0.892, live weight and chest girth (r = 0.860 and 0.872 and live weight and combined body measure (back length + chest girth (r = 0.877 and 0.941 and live weight and body volume (r = 0.905 and 0.954, respectively in female and male reindeer. Exponential regressions gave, however, the best estimations of live weight with combined body measure.

  14. DESIGN OF MINIMUM-WEIGHT DIFFUSION BATTERIES

    Science.gov (United States)

    Until recently, the measurement of particle sizes in aerosols was largely a laboratory exercise. Currently, however, particulates in the atmosphere and in the industrial exhaust gases are being monitored extensively in the field. While the weight and volume of laboratory apparatu...

  15. Average fetal depth in utero: data for estimation of fetal absorbed radiation dose

    International Nuclear Information System (INIS)

    Ragozzino, M.W.; Breckle, R.; Hill, L.M.; Gray, J.E.

    1986-01-01

    To estimate fetal absorbed dose from radiographic examinations, the depth from the anterior maternal surface to the midline of the fetal skull and abdomen was measured by ultrasound in 97 pregnant women. The relationships between fetal depth, fetal presentation, and maternal parameters of height, weight, anteroposterior (AP) thickness, gestational age, placental location, and bladder volume were analyzed. Maternal AP thickness (MAP) can be estimated from gestational age, maternal height, and maternal weight. Fetal midskull and abdominal depths were nearly equal. Fetal depth normalized to MAP was independent or nearly independent of maternal parameters and fetal presentation. These data enable a reasonable estimation of absorbed dose to fetal brain, abdomen, and whole body

  16. A Single Image Dehazing Method Using Average Saturation Prior

    Directory of Open Access Journals (Sweden)

    Zhenfei Gu

    2017-01-01

    Full Text Available Outdoor images captured in bad weather are prone to yield poor visibility, which is a fatal problem for most computer vision applications. The majority of existing dehazing methods rely on an atmospheric scattering model and therefore share a common limitation; that is, the model is only valid when the atmosphere is homogeneous. In this paper, we propose an improved atmospheric scattering model to overcome this inherent limitation. By adopting the proposed model, a corresponding dehazing method is also presented. In this method, we first create a haze density distribution map of a hazy image, which enables us to segment the hazy image into scenes according to the haze density similarity. Then, in order to improve the atmospheric light estimation accuracy, we define an effective weight assignment function to locate a candidate scene based on the scene segmentation results and therefore avoid most potential errors. Next, we propose a simple but powerful prior named the average saturation prior (ASP, which is a statistic of extensive high-definition outdoor images. Using this prior combined with the improved atmospheric scattering model, we can directly estimate the scene atmospheric scattering coefficient and restore the scene albedo. The experimental results verify that our model is physically valid, and the proposed method outperforms several state-of-the-art single image dehazing methods in terms of both robustness and effectiveness.

  17. Total volume versus bouts

    DEFF Research Database (Denmark)

    Chinapaw, Mai; Klakk, Heidi; Møller, Niels Christian

    2018-01-01

    BACKGROUND/OBJECTIVES: Examine the prospective relationship of total volume versus bouts of sedentary behaviour (SB) and moderate-to-vigorous physical activity (MVPA) with cardiometabolic risk in children. In addition, the moderating effects of weight status and MVPA were explored. SUBJECTS....../METHODS: Longitudinal study including 454 primary school children (mean age 10.3 years). Total volume and bouts (i.e. ≥10 min consecutive minutes) of MVPA and SB were assessed by accelerometry in Nov 2009/Jan 2010 (T1) and Aug/Oct 2010 (T2). Triglycerides, total cholesterol/HDL cholesterol ratio (TC:HDLC ratio......, with or without mutual adjustments between MVPA and SB. The moderating effects of weight status and MVPA (for SB only) were examined by adding interaction terms. RESULTS: Children engaged daily in about 60 min of total MVPA and 0-15 min/week in MVPA bouts. Mean total sedentary time was around 7 h/day with over 3...

  18. Weightlifting, weight training and injuries.

    Science.gov (United States)

    Basford, J R

    1985-08-01

    Although millions of men and women in the United States are regularly involved in some form of weightlifting, the average physician knows, and frequently cares, little about the sports involved. As a result, his or her knowledge of the medical and physiological issues involved is limited This article attempts to address this lack by beginning with a brief introductory section outlining some of the similarities differences between the major weight lifting approaches (power lifting, olympic lifting, weight training and body building). Next it reviews major issues and controversies such as age restrictions for lifters, physiological effects, drug use, potential strength gains and hypertrophy. Finally, it discusses some of the more frequent and unique injuries that can occur in lifters.

  19. Optimizing Prediction Using Bayesian Model Averaging: Examples Using Large-Scale Educational Assessments.

    Science.gov (United States)

    Kaplan, David; Lee, Chansoon

    2018-01-01

    This article provides a review of Bayesian model averaging as a means of optimizing the predictive performance of common statistical models applied to large-scale educational assessments. The Bayesian framework recognizes that in addition to parameter uncertainty, there is uncertainty in the choice of models themselves. A Bayesian approach to addressing the problem of model uncertainty is the method of Bayesian model averaging. Bayesian model averaging searches the space of possible models for a set of submodels that satisfy certain scientific principles and then averages the coefficients across these submodels weighted by each model's posterior model probability (PMP). Using the weighted coefficients for prediction has been shown to yield optimal predictive performance according to certain scoring rules. We demonstrate the utility of Bayesian model averaging for prediction in education research with three examples: Bayesian regression analysis, Bayesian logistic regression, and a recently developed approach for Bayesian structural equation modeling. In each case, the model-averaged estimates are shown to yield better prediction of the outcome of interest than any submodel based on predictive coverage and the log-score rule. Implications for the design of large-scale assessments when the goal is optimal prediction in a policy context are discussed.

  20. Estimation of standard liver volume in Chinese adult living donors.

    Science.gov (United States)

    Fu-Gui, L; Lu-Nan, Y; Bo, L; Yong, Z; Tian-Fu, W; Ming-Qing, X; Wen-Tao, W; Zhe-Yu, C

    2009-12-01

    To determine a formula predicting the standard liver volume based on body surface area (BSA) or body weight in Chinese adults. A total of 115 consecutive right-lobe living donors not including the middle hepatic vein underwent right hemi-hepatectomy. No organs were used from prisoners, and no subjects were prisoners. Donor anthropometric data including age, gender, body weight, and body height were recorded prospectively. The weights and volumes of the right lobe liver grafts were measured at the back table. Liver weights and volumes were calculated from the right lobe graft weight and volume obtained at the back table, divided by the proportion of the right lobe on computed tomography. By simple linear regression analysis and stepwise multiple linear regression analysis, we correlated calculated liver volume and body height, body weight, or body surface area. The subjects had a mean age of 35.97 +/- 9.6 years, and a female-to-male ratio of 60:55. The mean volume of the right lobe was 727.47 +/- 136.17 mL, occupying 55.59% +/- 6.70% of the whole liver by computed tomography. The volume of the right lobe was 581.73 +/- 96.137 mL, and the estimated liver volume was 1053.08 +/- 167.56 mL. Females of the same body weight showed a slightly lower liver weight. By simple linear regression analysis and stepwise multiple linear regression analysis, a formula was derived based on body weight. All formulae except the Hong Kong formula overestimated liver volume compared to this formula. The formula of standard liver volume, SLV (mL) = 11.508 x body weight (kg) + 334.024, may be applied to estimate liver volumes in Chinese adults.

  1. Weighted network modules

    International Nuclear Information System (INIS)

    Farkas, Illes; Abel, Daniel; Palla, Gergely; Vicsek, Tamas

    2007-01-01

    The inclusion of link weights into the analysis of network properties allows a deeper insight into the (often overlapping) modular structure of real-world webs. We introduce a clustering algorithm clique percolation method with weights (CPMw) for weighted networks based on the concept of percolating k-cliques with high enough intensity. The algorithm allows overlaps between the modules. First, we give detailed analytical and numerical results about the critical point of weighted k-clique percolation on (weighted) Erdos-Renyi graphs. Then, for a scientist collaboration web and a stock correlation graph we compute three-link weight correlations and with the CPMw the weighted modules. After reshuffling link weights in both networks and computing the same quantities for the randomized control graphs as well, we show that groups of three or more strong links prefer to cluster together in both original graphs

  2. Preventing Weight Gain

    Science.gov (United States)

    ... Local Programs Related Topics Diabetes Nutrition Preventing Weight Gain Language: English (US) Español (Spanish) Recommend on Facebook ... cancer. Choosing an Eating Plan to Prevent Weight Gain So, how do you choose a healthful eating ...

  3. Determination of the blood volume of rabbits (1963)

    International Nuclear Information System (INIS)

    Bernard, Y.; Pierotti, Th.; Rinaldi, R.

    1963-01-01

    The knowledge of the ratio of the blood volume to the weight of an animal is of a great deal in various experiments. Therefore authors have decided to determine this ratio for rabbits by using chromium 51. Results show that the blood volume represents about 54.4 g per kilogram of body weight. (authors) [fr

  4. Weight management in pregnancy

    OpenAIRE

    Olander, E. K.

    2015-01-01

    Key learning points:\\ud - Women who start pregnancy in an overweight or obese weight category have increased health risks\\ud - Irrespective of pre-pregnancy weight category, there are health risks associated with gaining too much weight in pregnancy for both mother and baby\\ud - There are currently no official weight gain guidelines for pregnancy in the UK, thus focus needs to be on supporting pregnant women to eat healthily and keep active

  5. Expressing intrinsic volumes as rotational integrals

    DEFF Research Database (Denmark)

    Auneau, Jeremy Michel; Jensen, Eva Bjørn Vedel

    2010-01-01

    A new rotational formula of Crofton type is derived for intrinsic volumes of a compact subset of positive reach. The formula provides a functional defined on the section of X with a j-dimensional linear subspace with rotational average equal to the intrinsic volumes of X. Simplified forms of the ...

  6. Gravimetric gas determinations for volume calibration

    International Nuclear Information System (INIS)

    Gibbs, P.W.

    1991-01-01

    Gravimetric measurements of gases is one of the methods available for calibrating gas volumes. By inputting a known quantity of gas and measuring the resulting pressure and temperature, the system volume can be calculated using gas law principles. Historically, this method has been less accurate due to the difficulty in the mass determination. This difficulty comes from several sources. Two examples are the large tare weight of the gas container relative to the weight of gas and the external volume of the gas container relative to the standards. The application of a gravimetric gas determination to tank volume calibrations at the savannah River Site is discussed. Mass determinations on a 25,00 gram gas container were such that a 1500 gram quantity of gas was routinely determined to within ±0.2 gram at the 99% confidence level. In this paper the weighting design and the methods used to address the difficulties of the mass determination are detailed

  7. 20 CFR 404.221 - Computing your average monthly wage.

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Computing your average monthly wage. 404.221... DISABILITY INSURANCE (1950- ) Computing Primary Insurance Amounts Average-Monthly-Wage Method of Computing Primary Insurance Amounts § 404.221 Computing your average monthly wage. (a) General. Under the average...

  8. Gradient Weight in Phonology

    Science.gov (United States)

    Ryan, Kevin Michael

    2011-01-01

    Research on syllable weight in generative phonology has focused almost exclusively on systems in which weight is treated as an ordinal hierarchy of clearly delineated categories (e.g. light and heavy). As I discuss, canonical weight-sensitive phenomena in phonology, including quantitative meter and quantity-sensitive stress, can also treat weight…

  9. Gestational weight gain.

    Science.gov (United States)

    Kominiarek, Michelle A; Peaceman, Alan M

    2017-12-01

    Prenatal care providers are advised to evaluate maternal weight at each regularly scheduled prenatal visit, monitor progress toward meeting weight gain goals, and provide individualized counseling if significant deviations from a woman's goals occur. Today, nearly 50% of women exceed their weight gain goals with overweight and obese women having the highest prevalence of excessive weight gain. Risks of inadequate weight gain include low birthweight and failure to initiate breast-feeding whereas the risks of excessive weight gain include cesarean deliveries and postpartum weight retention for the mother and large-for-gestational-age infants, macrosomia, and childhood overweight or obesity for the offspring. Prenatal care providers have many resources and tools to incorporate weight and other health behavior counseling into routine prenatal practices. Because many women are motivated to improve health behaviors, pregnancy is often considered the optimal time to intervene for issues related to eating habits and physical activity to prevent excessive weight gain. Gestational weight gain is a potentially modifiable risk factor for a number of adverse maternal and neonatal outcomes and meta-analyses of randomized controlled trials report that diet or exercise interventions during pregnancy can help reduce excessive weight gain. However, health behavior interventions for gestational weight gain have not significantly improved other maternal and neonatal outcomes and have limited effectiveness in overweight and obese women. Copyright © 2017 Elsevier Inc. All rights reserved.

  10. Average and local structure of α-CuI by configurational averaging

    International Nuclear Information System (INIS)

    Mohn, Chris E; Stoelen, Svein

    2007-01-01

    Configurational Boltzmann averaging together with density functional theory are used to study in detail the average and local structure of the superionic α-CuI. We find that the coppers are spread out with peaks in the atom-density at the tetrahedral sites of the fcc sublattice of iodines. We calculate Cu-Cu, Cu-I and I-I pair radial distribution functions, the distribution of coordination numbers and the distribution of Cu-I-Cu, I-Cu-I and Cu-Cu-Cu bond-angles. The partial pair distribution functions are in good agreement with experimental neutron diffraction-reverse Monte Carlo, extended x-ray absorption fine structure and ab initio molecular dynamics results. In particular, our results confirm the presence of a prominent peak at around 2.7 A in the Cu-Cu pair distribution function as well as a broader, less intense peak at roughly 4.3 A. We find highly flexible bonds and a range of coordination numbers for both iodines and coppers. This structural flexibility is of key importance in order to understand the exceptional conductivity of coppers in α-CuI; the iodines can easily respond to changes in the local environment as the coppers diffuse, and a myriad of different diffusion-pathways is expected due to the large variation in the local motifs

  11. High b-value diffusion-weighted imaging in progressive multifocal leukoencephalopathy in HIV patients

    International Nuclear Information System (INIS)

    Godi, Claudia; De Vita, Enrico; Davagnanam, Indran; Tombetti, Enrico; Haddow, Lewis; Jaeger, Hans Rolf

    2017-01-01

    An ill-defined hyperintense edge and hypointense core on diffusion-weighted imaging (DWI) is typical of progressive multifocal leukoencephalopathy (PML). We aimed to investigate whether a b-value of 3,000 s/mm"2 (b3000) can improve visualisation of PML, or provide different structural information compared to 1,000 s/mm"2 (b1000). We retrospectively identified HIV-positive patients with confirmed PML studied under a clinical protocol including both b1000 and b3000 DWI. The rim and core of each PML lesion and normal-appearing white matter (NAWM) were outlined on trace-weighted DWI. Signal intensities, apparent diffusion coefficient (ADC) values and volumes were measured and compared between b1000 and b3000. Nine lesions from seven patients were analysed. The rim and core were better visualised on b3000, with higher signal of the rim and lower signal of the core compared to NAWM. The hyperintense rim had non-restricted average ADCs, but included foci of low ADC on both b3000 and b1000. Despite similar total lesion volumes, b3000 displayed significantly larger core and smaller rim volumes than b1000. b3000 improves visualisation of this important PML hallmark. Moreover, b3000 partly reclassifies tissue from rim into core, and might provide potentially more accurate biomarkers of PML activity and prognosis. (orig.)

  12. High b-value diffusion-weighted imaging in progressive multifocal leukoencephalopathy in HIV patients

    Energy Technology Data Exchange (ETDEWEB)

    Godi, Claudia [San Raffaele Scientific Institute, Neuroradiology Department, Milan (Italy); The National Hospital for Neurology and Neurosurgery, Lysholm Department of Neuroradiology, London (United Kingdom); UCL Institute of Neurology, Neuroradiological Academic Unit, Department of Brain Repair and Rehabilitation, London (United Kingdom); De Vita, Enrico; Davagnanam, Indran [The National Hospital for Neurology and Neurosurgery, Lysholm Department of Neuroradiology, London (United Kingdom); UCL Institute of Neurology, Neuroradiological Academic Unit, Department of Brain Repair and Rehabilitation, London (United Kingdom); Tombetti, Enrico [Vita-Salute San Raffaele University, Milan (Italy); Haddow, Lewis [University College London, Centre for Sexual Health and HIV Research, Research Department of Infection and Population Health, London (United Kingdom); Jaeger, Hans Rolf [The National Hospital for Neurology and Neurosurgery, Lysholm Department of Neuroradiology, London (United Kingdom); UCL Institute of Neurology, Neuroradiological Academic Unit, Department of Brain Repair and Rehabilitation, London (United Kingdom); University College Hospital, Centre of Medical Imaging, London (United Kingdom)

    2017-09-15

    An ill-defined hyperintense edge and hypointense core on diffusion-weighted imaging (DWI) is typical of progressive multifocal leukoencephalopathy (PML). We aimed to investigate whether a b-value of 3,000 s/mm{sup 2} (b3000) can improve visualisation of PML, or provide different structural information compared to 1,000 s/mm{sup 2} (b1000). We retrospectively identified HIV-positive patients with confirmed PML studied under a clinical protocol including both b1000 and b3000 DWI. The rim and core of each PML lesion and normal-appearing white matter (NAWM) were outlined on trace-weighted DWI. Signal intensities, apparent diffusion coefficient (ADC) values and volumes were measured and compared between b1000 and b3000. Nine lesions from seven patients were analysed. The rim and core were better visualised on b3000, with higher signal of the rim and lower signal of the core compared to NAWM. The hyperintense rim had non-restricted average ADCs, but included foci of low ADC on both b3000 and b1000. Despite similar total lesion volumes, b3000 displayed significantly larger core and smaller rim volumes than b1000. b3000 improves visualisation of this important PML hallmark. Moreover, b3000 partly reclassifies tissue from rim into core, and might provide potentially more accurate biomarkers of PML activity and prognosis. (orig.)

  13. MRI to delineate the gross tumor volume of nasopharyngeal cancers: which sequences and planes should be used?

    Science.gov (United States)

    Popovtzer, Aron; Ibrahim, Mohannad; Tatro, Daniel; Feng, Felix Y; Ten Haken, Randall K; Eisbruch, Avraham

    2014-09-01

    Magnetic resonance imaging (MRI) has been found to be better than computed tomography for defining the extent of primary gross tumor volume (GTV) in advanced nasopharyngeal cancer. It is routinely applied for target delineation in planning radiotherapy. However, the specific MRI sequences/planes that should be used are unknown. Twelve patients with nasopharyngeal cancer underwent primary GTV evaluation with gadolinium-enhanced axial T1 weighted image (T1) and T2 weighted image (T2), coronal T1, and sagittal T1 sequences. Each sequence was registered with the planning computed tomography scans. Planning target volumes (PTVs) were derived by uniform expansions of the GTVs. The volumes encompassed by the various sequences/planes, and the volumes common to all sequences/planes, were compared quantitatively and anatomically to the volume delineated by the commonly used axial T1-based dataset. Addition of the axial T2 sequence increased the axial T1-based GTV by 12% on average (p = 0.004), and composite evaluations that included the coronal T1 and sagittal T1 planes increased the axial T1-based GTVs by 30% on average (p = 0.003). The axial T1-based PTVs were increased by 20% by the additional sequences (p = 0.04). Each sequence/plane added unique volume extensions. The GTVs common to all the T1 planes accounted for 38% of the total volumes of all the T1 planes. Anatomically, addition of the coronal and sagittal-based GTVs extended the axial T1-based GTV caudally and cranially, notably to the base of the skull. Adding MRI planes and sequences to the traditional axial T1 sequence yields significant quantitative and anatomically important extensions of the GTVs and PTVs. For accurate target delineation in nasopharyngeal cancer, we recommend that GTVs be outlined in all MRI sequences/planes and registered with the planning computed tomography scans.

  14. Quantified moving average strategy of crude oil futures market based on fuzzy logic rules and genetic algorithms

    Science.gov (United States)

    Liu, Xiaojia; An, Haizhong; Wang, Lijun; Guan, Qing

    2017-09-01

    The moving average strategy is a technical indicator that can generate trading signals to assist investment. While the trading signals tell the traders timing to buy or sell, the moving average cannot tell the trading volume, which is a crucial factor for investment. This paper proposes a fuzzy moving average strategy, in which the fuzzy logic rule is used to determine the strength of trading signals, i.e., the trading volume. To compose one fuzzy logic rule, we use four types of moving averages, the length of the moving average period, the fuzzy extent, and the recommend value. Ten fuzzy logic rules form a fuzzy set, which generates a rating level that decides the trading volume. In this process, we apply genetic algorithms to identify an optimal fuzzy logic rule set and utilize crude oil futures prices from the New York Mercantile Exchange (NYMEX) as the experiment data. Each experiment is repeated for 20 times. The results show that firstly the fuzzy moving average strategy can obtain a more stable rate of return than the moving average strategies. Secondly, holding amounts series is highly sensitive to price series. Thirdly, simple moving average methods are more efficient. Lastly, the fuzzy extents of extremely low, high, and very high are more popular. These results are helpful in investment decisions.

  15. Tailoring dietary approaches for weight loss.

    Science.gov (United States)

    Gardner, C D

    2012-07-01

    Although the 'Low-Fat' diet was the predominant public health recommendation for weight loss and weight control for the past several decades, the obesity epidemic continued to grow during this time period. An alternative 'low-carbohydrate' (Low-Carb) approach, although originally dismissed and even vilified, was comparatively tested in a series of studies over the past decade, and has been found in general to be as effective, if not more, as the Low-Fat approach for weight loss and for several related metabolic health measures. From a glass half full perspective, this suggests that there is more than one choice for a dietary approach to lose weight, and that Low-Fat and Low-Carb diets may be equally effective. From a glass half empty perspective, the average amount of weight lost on either of these two dietary approaches under the conditions studied, particularly when followed beyond 1 year, has been modest at best and negligible at worst, suggesting that the two approaches may be equally ineffective. One could resign themselves at this point to focusing on calories and energy intake restriction, regardless of macronutrient distributions. However, before throwing out the half-glass of water, it is worthwhile to consider that focusing on average results may mask important subgroup successes and failures. In all weight-loss studies, without exception, the range of individual differences in weight change within any particular diet groups is orders of magnitude greater than the average group differences between diet groups. Several studies have now reported that adults with greater insulin resistance are more successful with weight loss on a lower-carbohydrate diet compared with a lower-fat diet, whereas adults with greater insulin sensitivity are equally or more successful with weight loss on a lower-fat diet compared with a lower-carbohydrate diet. Other preliminary findings suggest that there may be some promise with matching individuals with certain genotypes to

  16. Yogurt and weight management.

    Science.gov (United States)

    Jacques, Paul F; Wang, Huifen

    2014-05-01

    A large body of observational studies and randomized controlled trials (RCTs) has examined the role of dairy products in weight loss and maintenance of healthy weight. Yogurt is a dairy product that is generally very similar to milk, but it also has some unique properties that may enhance its possible role in weight maintenance. This review summarizes the human RCT and prospective observational evidence on the relation of yogurt consumption to the management and maintenance of body weight and composition. The RCT evidence is limited to 2 small, short-term, energy-restricted trials. They both showed greater weight losses with yogurt interventions, but the difference between the yogurt intervention and the control diet was only significant in one of these trials. There are 5 prospective observational studies that have examined the association between yogurt and weight gain. The results of these studies are equivocal. Two of these studies reported that individuals with higher yogurt consumption gained less weight over time. One of these same studies also considered changes in waist circumference (WC) and showed that higher yogurt consumption was associated with smaller increases in WC. A third study was inconclusive because of low statistical power. A fourth study observed no association between changes in yogurt intake and weight gain, but the results suggested that those with the largest increases in yogurt intake during the study also had the highest increase in WC. The final study examined weight and WC change separately by sex and baseline weight status and showed benefits for both weight and WC changes for higher yogurt consumption in overweight men, but it also found that higher yogurt consumption in normal-weight women was associated with a greater increase in weight over follow-up. Potential underlying mechanisms for the action of yogurt on weight are briefly discussed.

  17. Relationships between feeding behavior and average daily gain in cattle

    Directory of Open Access Journals (Sweden)

    Bruno Fagundes Cunha Lage

    2013-12-01

    Full Text Available Several studies have reported relationship between eating behavior and performance in feedlot cattle. The evaluation of behavior traits demands high degree of work and trained manpower, therefore, in recent years has been used an automated feed intake measurement system (GrowSafe System ®, that identify and record individual feeding patterns. The aim of this study was to evaluate the relationship between feeding behavior traits and average daily gain in Nellore calves undergoing feed efficiency test. Date from 85 Nelore males was recorded during the feed efficiency test performed in 2012, at Centro APTA Bovinos de Corte, Instituto de Zootecnia, São Paulo State. Were analyzed the behavioral traits: time at feeder (TF, head down duration (HD, representing the time when the animal is actually eating, frequency of visits (FV and feed rate (FR calculated as the amount of dry matter (DM consumed by time at feeder (g.min-1. The ADG was calculated by linear regression of individual weights on days in test. ADG classes were obtained considering the average ADG and standard deviation (SD being: high ADG (>mean + 1.0 SD, medium ADG (± 1.0 SD from the mean and low ADG (0.05 among ADG classes for FV, indicating that these traits are not related to each other. These results shows that the ADG is related to the agility in eat food and not to the time spent in the bunk or to the number of visits in a range of 24 hours.

  18. Estimation of free volumes of polystyrene by positron annihilation life-time technique

    International Nuclear Information System (INIS)

    Li, Hong-Ling; Ujihira, Yusuke; Nanasawa, Atsushi.

    1996-01-01

    Differences of size, content, and size distribution of free volumes in linear and three-armed polystyrenes, synthesized by radical, and anionic processes, were observed by positron annihilation lifetime measurements. For the polystyrene samples of different architectures and molecular weight distributions, the temperature dependence of an average free volume radius was quite similar to each other. The radius increased with increasing temperature (T), from 0.27 nm (60 K) to 0.30 nm (glass transition temperature: T g = 363 K), then to 0.35 nm (423 K), showing αβ transition temperature about 300 K. With increasing T, the free volume content decreased from 35% (60 K) to 25% (260 K) for radically polymerized linear polystyrene and to 22% (320 K) for anionically polymerized three-armed polystyrene, and then turned to increase to 35% at 350 K and 400 K, respectively. In contrast, the content for anionically polymerized linear polystyrene decreased from 45% (60 K) to 33% (300 K) and turned to increase to 35% at 350-400 K. The free volume content decreased reciprocally with an increase in the molecular weight at 333 K, suggesting differences in molecular motion between the edge and middle portions of the chain molecule. (author)

  19. Stereological estimates of nuclear volume in squamous cell carcinoma of the uterine cervix and its precursors

    DEFF Research Database (Denmark)

    Sørensen, Flemming Brandt; Bichel, P; Jakobsen, A

    1991-01-01

    Using modern stereology, this study was carried out to obtain base-line data concerning three-dimensional, mean nuclear size in precancerous and invasive lesions of the uterine cervix. Unbiased estimates of the volume-weighted mean nuclear volume (nuclear vv) were obtained by point-sampling of nu......Using modern stereology, this study was carried out to obtain base-line data concerning three-dimensional, mean nuclear size in precancerous and invasive lesions of the uterine cervix. Unbiased estimates of the volume-weighted mean nuclear volume (nuclear vv) were obtained by point......-sampling of nuclear intercepts in 51 pre-treatment biopsies from patients with invasive squamous cell carcinomas (SCC). Vertical sections from 27 specimens with cervical intraepithelial neoplasia (CIN) grades I through III were also investigated, along with 10 CIN III associated with microinvasion (CIN III + M......). On average, nuclear vv was larger in SCC than in CIN III and CIN III + M together (2 P = 8.9 . 10(-5). A conspicuous overlap of nuclear vv existed between all investigated lesional groups. The reproducibility of estimates of nuclear vv in biopsies with SCC was acceptable (r = 0.85 and r = 0.84 in intra...

  20. Comparison of Magnetic Resonance Imaging and Computed Tomography for Breast Target Volume Delineation in Prone and Supine Positions

    Energy Technology Data Exchange (ETDEWEB)

    Pogson, Elise M. [Centre for Medical Radiation Physics, Faculty of Engineering and Information Sciences, University of Wollongong, Wollongong (Australia); Liverpool and Macarthur Cancer Therapy Centres, Liverpool (Australia); Ingham Institute for Applied Medical Research, Liverpool (Australia); Delaney, Geoff P. [Liverpool and Macarthur Cancer Therapy Centres, Liverpool (Australia); Ingham Institute for Applied Medical Research, Liverpool (Australia); South Western Sydney Clinical School, University of New South Wales, Sydney (Australia); School of Medicine, University of Western Sydney, Sydney (Australia); Ahern, Verity [Crown Princess Mary Cancer Care Centre, Westmead Hospital, Westmead (Australia); Boxer, Miriam M. [Liverpool and Macarthur Cancer Therapy Centres, Liverpool (Australia); South Western Sydney Clinical School, University of New South Wales, Sydney (Australia); Chan, Christine [Department of Radiology, Liverpool Hospital, Liverpool (Australia); David, Steven [Peter MacCallum Cancer Centre, Melbourne (Australia); Dimigen, Marion [Department of Radiology, Liverpool Hospital, Liverpool (Australia); Harvey, Jennifer A. [School of Medicine, University of Queensland, Herston (Australia); Princess Alexandra Hospital, Woolloongabba (Australia); Koh, Eng-Siew [Liverpool and Macarthur Cancer Therapy Centres, Liverpool (Australia); Ingham Institute for Applied Medical Research, Liverpool (Australia); South Western Sydney Clinical School, University of New South Wales, Sydney (Australia); Lim, Karen [Liverpool and Macarthur Cancer Therapy Centres, Liverpool (Australia); South Western Sydney Clinical School, University of New South Wales, Sydney (Australia); Papadatos, George [Liverpool and Macarthur Cancer Therapy Centres, Liverpool (Australia); and others

    2016-11-15

    Purpose: To determine whether T2-weighted MRI improves seroma cavity (SC) and whole breast (WB) interobserver conformity for radiation therapy purposes, compared with the gold standard of CT, both in the prone and supine positions. Methods and Materials: Eleven observers (2 radiologists and 9 radiation oncologists) delineated SC and WB clinical target volumes (CTVs) on T2-weighted MRI and CT supine and prone scans (4 scans per patient) for 33 patient datasets. Individual observer's volumes were compared using the Dice similarity coefficient, volume overlap index, center of mass shift, and Hausdorff distances. An average cavity visualization score was also determined. Results: Imaging modality did not affect interobserver variation for WB CTVs. Prone WB CTVs were larger in volume and more conformal than supine CTVs (on both MRI and CT). Seroma cavity volumes were larger on CT than on MRI. Seroma cavity volumes proved to be comparable in interobserver conformity in both modalities (volume overlap index of 0.57 (95% Confidence Interval (CI) 0.54-0.60) for CT supine and 0.52 (95% CI 0.48-0.56) for MRI supine, 0.56 (95% CI 0.53-0.59) for CT prone and 0.55 (95% CI 0.51-0.59) for MRI prone); however, after registering modalities together the intermodality variation (Dice similarity coefficient of 0.41 (95% CI 0.36-0.46) for supine and 0.38 (0.34-0.42) for prone) was larger than the interobserver variability for SC, despite the location typically remaining constant. Conclusions: Magnetic resonance imaging interobserver variation was comparable to CT for the WB CTV and SC delineation, in both prone and supine positions. Although the cavity visualization score and interobserver concordance was not significantly higher for MRI than for CT, the SCs were smaller on MRI, potentially owing to clearer SC definition, especially on T2-weighted MR images.