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Sample records for volume expansion ve

  1. [Role of paraventricular nucleus in natriuresis and diuresis induced by volume expansion in rabbits].

    Science.gov (United States)

    Zhang, B; Lin, M Z; Han, G C

    2000-02-01

    In sham-lesioned and paraventricular nucleus (PVN) lesioned rabbits, the peak increases of urine volume (UV) induced by volume expansion (VE) were 0.59+/-0.09 and 0.31+/-0.03 ml/min (P0.05). In rabbits with renal denervation there was no significant change in natriuretic response after PVN lesion (P>0.05), but lesion of PVN significantly attenuated diuretic response (P0.05). These results suggest that PVN is involved in the regulation of natriuresis and diuresis induced by VE, which are mediated by vagal afferent nerve, whereas the renal sympathetic efferent nerve may be involved in natriuretic response.

  2. Karhunen-Loève Expansion for the Second Order Detrended Brownian Motion

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    Yongchun Zhou

    2014-01-01

    Full Text Available Based on the norm in the Hilbert Space L2[0,1], the second order detrended Brownian motion is defined as the orthogonal component of projection of the standard Brownian motion into the space spanned by nonlinear function subspace. Karhunen-Loève expansion for this process is obtained together with the relationship of that of a generalized Brownian bridge. As applications, Laplace transform, large deviation, and small deviation are given.

  3. Entorhinal cortex volume in antipsychotic-naïve schizophrenia

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    Sam P Jose

    2012-01-01

    Full Text Available Background: Entorhinal cortex (ERC, a multimodal sensory relay station for the hippocampus, is critically involved in learning, emotion, and novelty detection. One of the pathogenetic mechanistic bases in schizophrenia is proposed to involve aberrant information processing in the ERC. Several studies have looked at cytoarchitectural and morphometric changes in the ERC, but results have been inconsistent possibly due to the potential confounding effects of antipsychotic treatment. Materials and Methods In this study, we have examined the entorhinal cortex volume in antipsychotic-naïve schizophrenia patients (n=40; M:F=22:18 in comparison with age, sex, and handedness, matched (as a group with healthy subjects (n=42; M:F=25:17 using a valid method. 3-Tesla MR images with 1-mm sections were used and the data was analyzed using the SPSS software. Results: Female schizophrenia patients (1.25±0.22 mL showed significant volume deficit in the right ERC in comparison with female healthy controls (1.45±0.34 mL (F=4.9; P=0.03, after controlling for the potential confounding effects of intracranial volume. However, male patients did not differ from male controls. The left ERC volume did not differ between patients and controls. Conclusions: Consistent with the findings of a few earlier studies we found a reduction in the right ERC volume in patients. However, this was limited to women. Contextually, our study finding supports the role for ERC deficit in schizophrenia pathogenesis - perhaps mediated through aberrant novelty detection. Sex-differential observation of ERC volume deficit in schizophrenia needs further studies.

  4. Multiresolution Analysis for Stochastic Finite Element Problems with Wavelet-Based Karhunen-Loève Expansion

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    Carsten Proppe

    2012-01-01

    Full Text Available Multiresolution analysis for problems involving random parameter fields is considered. The random field is discretized by a Karhunen-Loève expansion. The eigenfunctions involved in this representation are computed by a wavelet expansion. The wavelet expansion allows to control the spatial resolution of the problem. Fine and coarse scales are defined, and the fine scales are taken into account by projection operators. The influence of the truncation level for the wavelet expansion on the computed reliability is documented.

  5. Central administration of kisspeptin-10 inhibits natriuresis and diuresis induced by blood volume expansion in anesthetized male rats

    OpenAIRE

    Han, Xu; Yan, Ming; An, Xiao-fei; HE Ming; Yu, Jiang-Yi

    2009-01-01

    Aim: To investigate the possible role of hypothalamic kisspeptin in the regulation of body fluid metabolism and maintenance of internal homeostasis. Methods: Natriuresis and diuresis were induced by blood volume expansion (VE) in anesthetized male rats and kisspeptin-10 was intracerebroventricularly (icv) administered. Radioimmunoassay (RIA) was used to measure the plasma arginine vasopressin (AVP) and atrial natriuretic peptide (ANP) concentrations during the VE. The mediation of the renal s...

  6. Modified Karhunen-Loéve expansion for evaluating skin-colour-associated melanoma risk factors.

    Science.gov (United States)

    Cevenini, G; Borzelli, G; Rubegni, P; Massai, M R; Andreassi, L; Barbini, P

    2000-07-01

    An approach based on the modified Karhunen-Loéve expansion (MKLE) of constitutive and facultative skin colour data acquired by colorimeters in melanoma patients and healthy control subjects, was used to identify two colour features defining skin-colour-associated risk of melanoma. None of four common statistical classifiers trained on colour features were sufficiently accurate for allowing skin colour alone to be used for classification purposes, though a Bayesian quadratic classifier matched the transformed data well. This study supersedes the indeterminate character of most common clinical criteria based on qualitative factors and, irrespective of the results of classification, provides objective skin colour information for the prevention of melanoma.

  7. Cardiorenal-endocrine dynamics during and following volume expansion

    Energy Technology Data Exchange (ETDEWEB)

    Zimmerman, R.S.; Edwards, B.S.; Schwab, T.R.; Heublein, D.M.; Burnett, J.C. Jr.

    1987-02-01

    The relationship between atrial pressure, atrial natriuretic peptide (ANP), the renin-angiotensin-aldosterone system, and renal hemodynamic and excretory function was examined during and following acute 10% body weight saline volume expansion and measurements were made at 3.3, 6.6, and 10% body weight volume expansion in pentobarbital anesthetized dogs. Right atrial pressure (RAP), pulmonary capillary wedge pressure (PCWP), fractional excretion of Na (FE/sub Na/), and ANP all increased in parallel during volume expansion. Plasma renin activity (PRA) and aldosterone decreased in parallel during 10% volume expansion. ANP, PRA and aldosterone were measured by radioimmunoassay. Following 10% volume expansion, saline was infused at the peak urine flow rate to maintain peak volume expansion. Despite continued saline infusion, RAP, PCWP, and ANP decreased in parallel. In contrast, FE/sub Na/ remained increased, and aldosterone and PRA remained depressed. These studies demonstrate that atrial pressures, ANP, and FE/sub Na/ increase in parallel during volume expansion; this suggests a role for ANP in modulating acute atrial volume overload. During stable volume expansion periods, however, despite a decrease in ANP levels, Na excretion remains elevated, suggesting that non-ANP mechanisms may be important in maintaining natriuresis during stable volume expansion.

  8. Bayesian estimation of Karhunen-Loève expansions; A random subspace approach

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    Chowdhary, Kenny; Najm, Habib N.

    2016-08-01

    One of the most widely-used procedures for dimensionality reduction of high dimensional data is Principal Component Analysis (PCA). More broadly, low-dimensional stochastic representation of random fields with finite variance is provided via the well known Karhunen-Loève expansion (KLE). The KLE is analogous to a Fourier series expansion for a random process, where the goal is to find an orthogonal transformation for the data such that the projection of the data onto this orthogonal subspace is optimal in the L2 sense, i.e., which minimizes the mean square error. In practice, this orthogonal transformation is determined by performing an SVD (Singular Value Decomposition) on the sample covariance matrix or on the data matrix itself. Sampling error is typically ignored when quantifying the principal components, or, equivalently, basis functions of the KLE. Furthermore, it is exacerbated when the sample size is much smaller than the dimension of the random field. In this paper, we introduce a Bayesian KLE procedure, allowing one to obtain a probabilistic model on the principal components, which can account for inaccuracies due to limited sample size. The probabilistic model is built via Bayesian inference, from which the posterior becomes the matrix Bingham density over the space of orthonormal matrices. We use a modified Gibbs sampling procedure to sample on this space and then build probabilistic Karhunen-Loève expansions over random subspaces to obtain a set of low-dimensional surrogates of the stochastic process. We illustrate this probabilistic procedure with a finite dimensional stochastic process inspired by Brownian motion.

  9. Nonlinear system stochastic response determination via fractional equivalent linearization and Karhunen-Loève expansion

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    Dai, Hongzhe; Zheng, Zhibao; Wang, Wei

    2017-08-01

    In this paper, a novel fractional equivalent linearization (EL) approach is developed by incorporating a fractional derivative term into the classical linearization equation. Due to the introduction of the fractional derivative term, the accuracy of the new linearization is improved, illustrated by a Duffing oscillator that is subjected to a harmonic excitation. Furthermore, a new method for solving stochastic response of nonlinear SDOF system is developed by combining Karhunen-Loève (K-L) expansion and fractional EL. The method firstly decomposes the stochastic excitation in terms of a set of random variables and deterministic sub-excitations using K-L expansion, and then construct sub-fractional equivalent linear system according to each sub-excitation by fractional EL, the response of the original nonlinear system is finally approximated as the weighed summation of the deterministic response of each sub-system multiplied by the corresponding random variable. The random nature of the final response comes from the set of random variables that is obtained in K-L expansion. In this way, the stochastic response computation is converted to a set of deterministic response analysis problems. The effectiveness of the developed method is demonstrated by a Duffing oscillator that is subjected to stochastic excitation modeled by Winner process. The results are compared with the numerical method and Monte Carlo simulation (MCS).

  10. Review article: volume expansion in patients with cirrhosis

    DEFF Research Database (Denmark)

    Henriksen, Jens Henrik; Kiszka-Kanowitz, Marianne; Bendtsen, Flemming

    2002-01-01

    , and in advanced cirrhosis, especially the non-central parts of the circulation, including the splanchnic blood volume, are expanded by a volume load. Infusion of oncotic material (preferably albumin) is important in the prevention of post-paracentesis circulatory dysfunction. In conclusion, volume expansion...

  11. On the thermal expansion of nanohole free volume in perfluoropolyethers.

    Science.gov (United States)

    Consolati, G

    2005-05-26

    To determine the free volume in polymers, positron annihilation lifetime spectroscopy data are transformed into nanohole volumes by modeling the cavities as spheres or, more generally, using geometries assuming an isotropic thermal expansion. However, this guess could be unrealistic owing to the irregular shape of nanoholes and constrained movements of the macromolecules. In this work, it is shown that a comparison of hole-lattice theory with positron and dilatometric data for a homologous series of perfluoropolyethers supplies information on the anisotropic expansion of nanoholes; the relation between volume and typical unconstrained size of the cavities can be expressed by a power law with noninteger exponents.

  12. Prevention of contrast-induced nephropathy with volume expansion.

    Science.gov (United States)

    Weisbord, Steven D; Palevsky, Paul M

    2008-01-01

    Contrast-induced nephropathy is one of the few preventable forms of acute kidney injury. Several pharmacologic agents have been evaluated for the prevention of contrast-induced nephropathy, yet disappointingly, few have been shown conclusively to reduce the risk for this condition. A series of studies have demonstrated that volume expansion, particularly with intravenous fluids, is an effective intervention to reduce the risk for contrast-induced nephropathy. This article reviews the clinical trials that have assessed the role of volume expansion for the prevention of contrast-induced nephropathy. The administration of isotonic sodium chloride before and after radiocontrast injection seems to be more protective than equivalent volumes of hypotonic saline and, when feasible, should be administered over a sustained period of time. Recent clinical trials suggested that an abbreviated regimen of intravenous sodium bicarbonate may be superior to a comparable protocol of sodium chloride. Although a small number of studies have found that volume supplementation by mouth may be effective in preventing contrast-induced nephropathy, the routine use of enteral fluids or solute in lieu of intravenous fluids in high-risk patients cannot be recommended at this time. Rather, liberal oral fluid and solute intake should complement intravenous fluid administration to minimize risk. Future studies will be required to define clearly the optimal prophylactic intravenous fluid regimen for contrast-induced nephropathy and further delineate the independent role of oral volume expansion for the prevention of this condition.

  13. The Combination of Tissue Dissection and External Volume Expansion Generates Large Volumes of Adipose Tissue.

    Science.gov (United States)

    He, Yunfan; Dong, Ziqing; Xie, Gan; Zhou, Tao; Lu, Feng

    2017-04-01

    Noninvasive external volume expansion device has been applied to stimulate nonsurgical breast enlargement in clinical settings. Although previous results demonstrate the capacity of external volume expansion to increase the number of adipocytes, this strategy alone is insufficient to reconstruct soft-tissue defects or increase breast mass. The authors combined a minimally invasive tissue dissection method with external volume expansion to generate large volumes of adipose tissue. In vitro, various densities of adipose-derived stem cells were prepared to evaluate relations between cell contacts and cell proliferation. In vivo, dorsal adipose tissue of rabbits was thoroughly dissected and the external volume expansion device was applied to maintain the released state. External volume expansion without tissue dissection served as the control. In the dissection group, the generated adipose tissue volume was much larger than that in the control group at all time points. A larger number of proliferating cells appeared in the dissection samples than in the control samples at the early stage after tissue dissection. At low cell density, adipose-derived stem cells displayed an increasing proliferation rate compared to high cell density. Protein expression analysis revealed that cell proliferation was mediated by a similar mechanism both in vivo and in vitro, involving the release of cell contact inhibition and Hippo/Yes-associated protein pathway activation. Adipose tissue dissection releases cell-to-cell contacts and induces adipose-derived stem cell proliferation. Preexpanded adipose-derived stem cells undergo adipogenesis under the adipogenic environment created by external volume expansion, leading to better adipose regeneration compared with the control.

  14. Applying dynamic parameters to predict hemodynamic response to volume expansion in spontaneously breathing patients with septic shock.

    Science.gov (United States)

    Lanspa, Michael J; Grissom, Colin K; Hirshberg, Eliotte L; Jones, Jason P; Brown, Samuel M

    2013-02-01

    Volume expansion is a mainstay of therapy in septic shock, although its effect is difficult to predict using conventional measurements. Dynamic parameters, which vary with respiratory changes, appear to predict hemodynamic response to fluid challenge in mechanically ventilated, paralyzed patients. Whether they predict response in patients who are free from mechanical ventilation is unknown. We hypothesized that dynamic parameters would be predictive in patients not receiving mechanical ventilation. This is a prospective, observational, pilot study. Patients with early septic shock and who were not receiving mechanical ventilation received 10-mL/kg volume expansion (VE) at their treating physician's discretion after initial resuscitation in the emergency department. We used transthoracic echocardiography to measure vena cava collapsibility index and aortic velocity variation before VE. We used a pulse contour analysis device to measure stroke volume variation (SVV). Cardiac index was measured immediately before and after VE using transthoracic echocardiography. Hemodynamic response was defined as an increase in cardiac index 15% or greater. Fourteen patients received VE, five of whom demonstrated a hemodynamic response. Vena cava collapsibility index and SVV were predictive (area under the curve = 0.83, 0.92, respectively). Optimal thresholds were calculated: vena cava collapsibility index, 15% or greater (positive predictive value, 62%; negative predictive value, 100%; P = 0.03); SVV, 17% or greater (positive predictive value 100%, negative predictive value 82%, P = 0.03). Aortic velocity variation was not predictive. Vena cava collapsibility index and SVV predict hemodynamic response to fluid challenge patients with septic shock who are not mechanically ventilated. Optimal thresholds differ from those described in mechanically ventilated patients.

  15. Applying dynamic parameters to predict hemodynamic response to volume expansion in spontaneously breathing patients with septic shock

    Science.gov (United States)

    Lanspa, Michael J.; Grissom, Colin K.; Hirshberg, Eliotte L.; Jones, Jason P.; Brown, Samuel M.

    2013-01-01

    Background Volume expansion is a mainstay of therapy in septic shock, although its effect is difficult to predict using conventional measurements. Dynamic parameters, which vary with respiratory changes, appear to predict hemodynamic response to fluid challenge in mechanically ventilated, paralyzed patients. Whether they predict response in patients who are free from mechanical ventilation is unknown. We hypothesized that dynamic parameters would be predictive in patients not receiving mechanical ventilation. Methods This is a prospective, observational, pilot study. Patients with early septic shock and who were not receiving mechanical ventilation received 10 ml/kg volume expansion (VE) at their treating physician's discretion after initial resuscitation in the emergency department. We used transthoracic echocardiography to measure vena cava collapsibility index (VCCI) and aortic velocity variation (AoVV) prior to VE. We used a pulse contour analysis device to measure stroke volume variation (SVV). Cardiac index was measured immediately before and after VE using transthoracic echocardiography. Hemodynamic response was defined as an increase in cardiac index ≥ 15%. Results 14 patients received VE, 5 of which demonstrated a hemodynamic response. VCCI and SVV were predictive (Area under curve = 0.83, 0.92, respectively). Optimal thresholds were calculated: VCCI ≥ 15% (Positive predictive value, PPV 62%, negative predictive value, NPV 100%, p = 0.03); SVV ≥ 17% (PPV 100%, NPV 82%, p = 0.03). AoVV was not predictive. Conclusions VCCI and SVV predict hemodynamic response to fluid challenge patients with septic shock who are not mechanically ventilated. Optimal thresholds differ from those described in mechanically ventilated patients. PMID:23324885

  16. Lens array fabrication method with volume expansion property of PDMS

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    Jang, WonJae; Kim, Junoh; Lee, Muyoung; Lee, Jooho; Bang, Yousung; Won, Yong Hyub

    2016-03-01

    Conventionally, poly (dimethylsiloxane) lens array is fabricated by replica molding. In this paper, we describe simple method for fabricating lens array with expanding property of PDMS. The PDMS substrate is prepared by spin coating on cleaned glass. After spin coating PDMS, substrate is treated with O2 plasma to promote adhesion between PDMS substrate and photoresist pattern on it. Positive photoresist az-4330 and AZ 430K developer is used for patterning on PDMS. General photolithography process is used to patterning. Then patterned PDMS substrate is dipped to 1- Bromododecane bath. During this process, patterned photoresist work as a barrier and prevent blocked PDMS substrate from reaction with 1-Bromododecane. Unblocked part of PDMS directly react with 1-Bromododecane and results in expanded PDMS volume. The expansion of PDMS is depends on absorbed 1-Bromododecane volume, dipping time and ratio of block to open area. The focal length of lens array is controlled by those PDMS expansion factors. Scale of patterned photoresist determine a diameter of each lens. The expansion occurs symmetrically at center of unblocked PDMS and 1-Bromododecane interface. As a result, the PDMS lens array is achieved by this process.

  17. Effect of volume expansion on systemic hemodynamics and central and arterial blood volume in cirrhosis

    DEFF Research Database (Denmark)

    Møller, Søren; Bendtsen, Flemming; Henriksen, Jens Henrik

    1995-01-01

    and in controls. METHODS: Thirty-nine patients with cirrhosis (12 patients with Child-Turcotte class A, 14 with class B, and 13 with class C) and 6 controls were studied. During hepatic vein catheterization, cardiac output, systemic vascular resistance, central and arterial blood volume, noncentral blood volume...... in patients with either class B or class C. Conversely, the noncentral blood volume increased in patients with class B and C. In both patients and controls, the cardiac output increased and the systemic vascular resistance decreased, whereas the mean arterial blood pressure did not change significantly......BACKGROUND & AIMS: Systemic vasodilatation in cirrhosis may lead to hemodynamic alterations with reduced effective blood volume and decreased arterial blood pressure. This study investigates the response of acute volume expansion on hemodynamics and regional blood volumes in patients with cirrhosis...

  18. Altitude acclimatization and blood volume: effects of exogenous erythrocyte volume expansion

    DEFF Research Database (Denmark)

    Sawka, M N; Young, Jette Feveile; Rock, P B;

    1996-01-01

    We studied sea-level residents during 13 days of altitude acclimatization to determine 1) altitude acclimatization effects on erythrocyte volume and plasma volume, 2) if exogenous erythrocyte volume expansion alters subsequent erythrocyte volume and plasma volume adaptations, 3) if an increased...... blood oxygen content alters erythropoietin responses during altitude acclimatization, and 4) mechanisms responsible for plasma loss at altitude. Sixteen healthy men had a series of hematologic measurements made at sea level, on the first and ninth days of altitude (4,300 m) residence, and after...... had no effect; in addition, initially at altitude, blood oxygen content was 8% higher in erythrocyte-infused than in saline-infused subjects. The new findings regarding altitude acclimatization are summarized as follows: 1) erythrocyte volume does not change during the first 13 days...

  19. PLASMA VOLUME EXPANSION 24-HOURS POST-EXERCISE: EFFECT OF DOUBLING THE VOLUME OF REPLACEMENT FLUID

    Directory of Open Access Journals (Sweden)

    Bartholomew Kay

    2005-06-01

    Full Text Available The effects of two volumes (1.5 L or 3.0 L of commercially available electrolyte beverage (1.44 mM·L-1 Na+ taken during a 24-hour recovery period post-exercise, on plasma volume (PV expansion 24-hours post-exercise were assessed. A simple random-order crossover research design was used. Subjects (n = 9 males: age 21 ± 4 years, body mass 80.0 ± 9.0 kg, peak incremental 60-second cycling power output 297 ± 45 W [means ± SD] completed an identical exercise protocol conducted in hot ambient conditions (35oC, 50% relative humidity on two occasions; separated by 7-days. On each occasion, subjects received a different volume of 24-hour fluid intake (commercial beverage in random order. In each case, the fluid was taken in five equal aliquots over 24-hours. PV expansions 24-hours post-exercise were estimated from changes in haemoglobin and haematocrit. Dependent t-testing revealed no significant differences in PV expansions between trials, however a significant expansion with respect to zero was identified in the 3.0 L trial only. Specifically, PV expansions (% were; 1.5 L trial: (mean ± SE 2.3 ± 2.0 (not significant with respect to zero, 3.0 L trial: 5.0 ± 2.0 (p < 0.05, with respect to zero. Under the conditions imposed in the current study, ingesting the greater volume of the beverage lead to larger mean PV expansion

  20. Expansion of extracellular volume in early polycystic kidney disease.

    Science.gov (United States)

    Danielsen, H; Pedersen, E B; Nielsen, A H; Herlevsen, P; Kornerup, H J; Posborg, V

    1986-01-01

    Blood volume (BV), extracellular volume (ECV), blood pressure (BP), creatinine clearance (CCr), plasma levels of angiotensin II (AII), aldosterone (Aldo) and arginine vasopressin (AVP), and serum osmolality (Sosm) were determined in 18 patients with adult polycystic kidney disease, 8 normotensive (group I), 10 hypertensive (group II), and in 11 control subjects (group III). ECV but not BV was increased in group I compared with group III, whereas BV and ECV did not differ significantly between groups II and III. In group II, Aldo and AVP were increased and AII tended to be increased, while in group I the hormone levels did not differ significantly from those in group III. Sosm did not differ significantly between the groups. In the combined patient group, CCr correlated positively with BV and ECV and negatively with BP. In the patients, AII and AVP were positively correlated with BP but not with CCr. The results suggest that both the renin-angiotensin system and AVP might be involved in the BP elevation, whereas expansion of ECV can be found without an increase in BP.

  1. Use of steel slag as a granular material: volume expansion prediction and usability criteria.

    Science.gov (United States)

    Wang, George; Wang, Yuhong; Gao, Zhili

    2010-12-15

    The theoretical equation for predicting volume expansion of steel slag is deduced based on both chemical reaction and physical changes of free lime in steel slag during the hydration process. Laboratory volume expansion testing is conducted to compare the results with the theoretical volume expansion. It is proved that they correlated well. It is furthermore experimentally proved that certain volume expansion of steel slag can be absorbed internally by the void volume in bulk steel slag under external surcharge weight making the apparent volume expansion equal zero. The minimum (lowest) absorbable void volume is approximately 7.5%, which is unrelated to the free lime content. A usability criterion is then developed based on the volume expansion of steel slag (%) and the minimum percentage of the volume that can take the volume expansion of steel slag (%). Eventually the criterion (relationship) is established based on the free lime content, the specific gravity and bulk relative gravity of a specific steel slag sample. The criteria can be used as guidance and specification for the use of steel slag and other expansion-prone nonferrous slags, copper, nickel for instance as a granular material in highway construction.

  2. Reduced anterior cingulate gray matter volume in treatment-naïve clinically depressed adolescents

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    Justine Nienke Pannekoek

    2014-01-01

    Full Text Available Adolescent depression is associated with increased risk for suicidality, social and educational impairment, smoking, substance use, obesity, and depression in adulthood. It is of relevance to further our insight in the neurobiological mechanisms underlying this disorder in the developing brain, as this may be essential to optimize treatment and prevention of adolescent depression and its negative clinical trajectories. The equivocal findings of the limited number of studies on neural abnormalities in depressed youth stress the need for further neurobiological investigation of adolescent depression. We therefore performed a voxel-based morphometry study of the hippocampus, amygdala, superior temporal gyrus, and anterior cingulate cortex (ACC in 26 treatment-naïve, clinically depressed adolescents and 26 pair-wise matched healthy controls. Additionally, an exploratory whole-brain analysis was performed. Clinically depressed adolescents showed a volume reduction of the bilateral dorsal ACC compared to healthy controls. However, no association was found between gray matter volume of the ACC and clinical severity scores for depression or anxiety. Our finding of a smaller ACC in clinically depressed adolescents is consistent with literature on depressed adults. Future research is needed to investigate if gray matter abnormalities precede or follow clinical depression in adolescents.

  3. Reduced anterior cingulate gray matter volume in treatment-naïve clinically depressed adolescents☆

    Science.gov (United States)

    Pannekoek, Justine Nienke; van der Werff, Steven J.A.; van den Bulk, Bianca G.; van Lang, Natasja D.J.; Rombouts, Serge A.R.B.; van Buchem, Mark A.; Vermeiren, Robert R.J.M.; van der Wee, Nic J.A.

    2014-01-01

    Adolescent depression is associated with increased risk for suicidality, social and educational impairment, smoking, substance use, obesity, and depression in adulthood. It is of relevance to further our insight in the neurobiological mechanisms underlying this disorder in the developing brain, as this may be essential to optimize treatment and prevention of adolescent depression and its negative clinical trajectories. The equivocal findings of the limited number of studies on neural abnormalities in depressed youth stress the need for further neurobiological investigation of adolescent depression. We therefore performed a voxel-based morphometry study of the hippocampus, amygdala, superior temporal gyrus, and anterior cingulate cortex (ACC) in 26 treatment-naïve, clinically depressed adolescents and 26 pair-wise matched healthy controls. Additionally, an exploratory whole-brain analysis was performed. Clinically depressed adolescents showed a volume reduction of the bilateral dorsal ACC compared to healthy controls. However, no association was found between gray matter volume of the ACC and clinical severity scores for depression or anxiety. Our finding of a smaller ACC in clinically depressed adolescents is consistent with literature on depressed adults. Future research is needed to investigate if gray matter abnormalities precede or follow clinical depression in adolescents. PMID:24501702

  4. Acute volume expansion attenuates hyperthermia-induced reductions in cerebral perfusion during simulated hemorrhage

    DEFF Research Database (Denmark)

    Schlader, Zachary J; Seifert, Thomas; Wilson, Thad E

    2013-01-01

    Hyperthermia reduces the capacity to withstand a simulated hemorrhagic challenge, but volume loading preserves this capacity. This study tested the hypotheses that acute volume expansion during hyperthermia increases cerebral perfusion and attenuates reductions in cerebral perfusion during a simu...

  5. Finite-volume cumulant expansion in QCD-colorless plasma

    Energy Technology Data Exchange (ETDEWEB)

    Ladrem, M. [Taibah University, Physics Department, Faculty of Science, Al-Madinah, Al-Munawwarah (Saudi Arabia); Physics Department, Algiers (Algeria); ENS-Vieux Kouba (Bachir El-Ibrahimi), Laboratoire de Physique et de Mathematiques Appliquees (LPMA), Algiers (Algeria); Ahmed, M.A.A. [Taibah University, Physics Department, Faculty of Science, Al-Madinah, Al-Munawwarah (Saudi Arabia); ENS-Vieux Kouba (Bachir El-Ibrahimi), Laboratoire de Physique et de Mathematiques Appliquees (LPMA), Algiers (Algeria); Taiz University in Turba, Physics Department, Taiz (Yemen); Alfull, Z.Z. [Taibah University, Physics Department, Faculty of Science, Al-Madinah, Al-Munawwarah (Saudi Arabia); Cherif, S. [ENS-Vieux Kouba (Bachir El-Ibrahimi), Laboratoire de Physique et de Mathematiques Appliquees (LPMA), Algiers (Algeria); Ghardaia University, Sciences and Technologies Department, Ghardaia (Algeria)

    2015-09-15

    Due to the finite-size effects, the localization of the phase transition in finite systems and the determination of its order, become an extremely difficult task, even in the simplest known cases. In order to identify and locate the finite-volume transition point T{sub 0}(V) of the QCD deconfinement phase transition to a colorless QGP, we have developed a new approach using the finite-size cumulant expansion of the order parameter and the L{sub mn}-method. The first six cumulants C{sub 1,2,3,4,5,6} with the corresponding under-normalized ratios (skewness Σ, kurtosis κ, pentosis Π{sub ±}, and hexosis H{sub 1,2,3}) and three unnormalized combinations of them, (O = σ{sup 2}κΣ{sup -1},U = σ{sup -2}Σ{sup -1},N = σ{sup 2}κ) are calculated and studied as functions of (T, V). A new approach, unifying in a clear and consistent way the definitions of cumulant ratios, is proposed.Anumerical FSS analysis of the obtained results has allowed us to locate accurately the finite-volume transition point. The extracted transition temperature value T{sub 0}(V) agrees with that expected T{sub 0}{sup N}(V) from the order parameter and the thermal susceptibility χ{sub T} (T, V), according to the standard procedure of localization to within about 2%. In addition to this, a very good correlation factor is obtained proving the validity of our cumulants method. The agreement of our results with those obtained by means of other models is remarkable. (orig.)

  6. Finite Volume Cumulant Expansion in QCD-Colorless Plasma

    CERN Document Server

    Ladrem, M; Al-Full, Z; Cherif, S

    2015-01-01

    Due to the finite size effects, the localisation of the phase transition in finite systems and the determination of its order, become an extremely difficult task, even in the simplest known cases. In order to identify and locate the finite volume transition point $T_{0}(V)$ of the QCD deconfinement phase transition to a Colorless QGP, we have developed a new approach using the finite size cumulant expansion of the order parameter and the $L_{mn}$-method. The first six cumulants $C_{1,2,3,4,5,6}$ with the corresponding under-normalized ratios(skewness $\\Sigma$, kurtosis $\\kappa$ ,pentosis $\\Pi_{\\pm}$ and hexosis $\\mathcal{H}_{1,2,3}$) and three unnormalized combinations of them ($\\mathcal{O}={\\mathcal{\\sigma }^{2} \\mathcal{\\kappa } }{\\mathbf{\\Sigma }^{-1} }$, $\\mathcal{U} ={\\mathcal{\\sigma }^{-2} \\mathbf{\\Sigma }^{-1} }$, $\\mathcal{N} = \\mathcal{\\sigma }^{2} \\mathcal{\\kappa }$) are calculated and studied as functions of $(T,V)$. A new approach, unifying in a clear and consistent way the definitions of cumulant...

  7. Simulation of Matched Field Processing Localization Based on Empirical Mode Decomposition and Karhunen-Loève Expansion in Underwater Waveguide Environment

    Directory of Open Access Journals (Sweden)

    Qin Jiang

    2010-01-01

    Full Text Available Mismatch problem has been one of important issues of matched field processing for underwater source detection. Experimental use of MFP has shown that robust range and depth localization is difficult to achieve. In many cases this is due to uncertainty in the environmental inputs required by acoustic propagation models. The paper presents that EMD (Empirical mode decomposition processing underwater acoustic signals is motivated because it is well suited for removing specific unwanted signal components that may vary spectrally. And the Karhunen-Loève expansion is applied on sample covariance matrix to gain a relatively uncorrupted signal. The EMD denoising scheme is combined with Karhunen-Loève expansion to improve underwater target localization performance of matched field processing (MFP. The robustness and effectiveness of the proposed method is tested by the benchmark cases numerical simulation when there had large environmental parameter uncertainties of the acoustic waveguide.

  8. Clinical correlates of thalamus volume deficits in anti-psychotic-naïve schizophrenia patients: A 3-Tesla MRI study.

    Science.gov (United States)

    Rao, Naren P; Kalmady, Sunil; Arasappa, Rashmi; Venkatasubramanian, Ganesan

    2010-07-01

    Thalamus, the sensory and motor gateway to the cortex, plays an important role in cognitive and perceptual disturbances in schizophrenia. Studies examining the volume of the thalamus in schizophrenia have reported conflicting findings due to the presence of potential confounding factors such as low-resolution imaging and anti-psychotics. The thalamus volume in anti-psychotic-naïve patients determined using high-resolution 3-Tesla magnetic resonance imaging (MRI) has not yet been examined. Using 3-Tesla MRI, this study for the first time examined anti-psychotic-naïve schizophrenia patients (n=18; M:F:11:7) in comparison with healthy controls (n=19;M:F:9:10) group-matched for age, sex, handedness, education, and socioeconomic status. The volume of the thalamus was measured using a three-dimensional, interactive, semi-automated analysis with good inter-rater and intra-rater reliability. Psychopathology was assessed using the Scale for Assessment of Negative Symptoms (SANS) and the Scale for Assessment of Positive Symptoms (SAPS). Right, left, and total thalamus volumes of patients were significantly smaller than those of controls after controlling for the potential confounding effect of intracranial volume. Thalamus volumes had significant positive correlation with positive symptoms score (SAPS) and significant negative correlation with negative symptoms score (SANS). Thalamus volume deficits in anti-psychotic-naïve schizophrenia patients support a neurodevelopmental pathogenesis. The contrasting correlation of thalamus volume deficits with psychopathology scores suggests that contrasting pruning aberrations underlie symptom genesis in schizophrenia.

  9. Hormonal and electrolyte responses to acute isohemic volume expansion in unanesthetized rats

    Science.gov (United States)

    Chenault, V. M.; Morris, M.; Lynch, C. D.; Maultsby, S. J.; Hutchins, P. M.

    1993-01-01

    This study was undertaken to explore the time course of the metabolic response to isohemic blood volume expansion (30%) in normotensive, unanesthetized Sprague-Dawley rats. Whole blood, drawn from a femoral artery catheter of conscious donor rats, was infused into the jugular vein of recipient rats. Blood samples were drawn from a carotid artery of recipient rats at time points beginning immediately post-volume expansion (IPVE) up through 5 days post-volume expansion (PVE). To characterize the attendant compensatory mechanisms, the plasma concentrations of electrolytes and fluid regulatory hormones were determined. Hematocrit began to raise IPVE and was significantly elevated above control IPVE 20, 30, 40, 60, and 90 min, and 2, 4, 6, 8, 12, and 24 hr PVE. Consistent with our current understanding of the hormonal response to excess volume, atrial natriuretic factor was significantly increased above the prevolume expansion (control) values 0-30 min PVE. Surprisingly, plasma aldosterone levels were significantly increased above control at 20 and 30 min and 6 hr PVE, whereas plasma renin activity was significantly decreased 30-40 min PVE. Plasma sodium was not changed from control values except for a significant increase at 6 hr post-volume expansion. Plasma potassium, osmolality, and arginine vasopressin levels were not altered by the volume expansion. These studies delineate the physiologic time scheme operative in the regulation of fluid volume during acute ischemic volume expansion.

  10. The importance of plasma volume expansion and nutrition in twin pregnancy.

    Science.gov (United States)

    Campbell, D M; MacGillivray, I

    1984-01-01

    Physiological adaptation including expansion in plasma volume is exaggerated in women with twin pregnancies. In singleton pregnancy and multiparous twin pregnancies there is an association between plasma volume expansion and birth weight, but this is not so in primigravid twin pregnancies. Women with twin pregnancies have a similar dietary intake to singleton pregnancies, but it is not known whether there are differences with parity or zygosity. Absorption and utilisation of nutrients may be increased to meet demands for extra fetal growth. Nutrient supply and plasma volume expansion will be further discussed and their association with birth weight presented.

  11. Paradoxical relationship between atriopeptin plasma levels and diuresis-natriuresis induced by acute volume expansion.

    OpenAIRE

    Sakata, M.; Greenwald, J E; Needleman, P

    1988-01-01

    Surgical removal of one or both atrial appendages was employed in rats to reduce the intrinsic stores of atriopeptin (AP). In conscious rats (with intact baroreceptor reflexes), bilateral or unilateral atrial appendectomy suppressed the diuresis and natriuresis produced by acute volume expansion. Surprisingly, volume expansion (with 4% bovine serum albumin in saline at 1.5 ml/kg per min for 15 min) did not result in an increase in plasma AP immunoreactivity (APir) in control or atrial-appende...

  12. F-Area Northeast Expansion Report, Volumes 1

    Energy Technology Data Exchange (ETDEWEB)

    Syms, F.H.

    1999-08-23

    A geotechnical program has been complexed in F-Area at the Savannah River Site in South Carolina. This program investigated the subsurface conditions for the area known as the ''northeast expansion'' located in the F-Area.

  13. Dermatoglyphic correlates of hippocampus volume: Evaluation of aberrant neurodevelopmental markers in antipsychotic-naïve schizophrenia.

    Science.gov (United States)

    Kalmady, Sunil V; Shivakumar, Venkataram; Gautham, S; Arasappa, Rashmi; Jose, Dania A; Venkatasubramanian, Ganesan; Gangadhar, B N

    2015-10-30

    Schizophrenia is a disorder of aberrant neurodevelopment is marked by abnormalities in brain structure and dermatoglyphic traits. However, the link between these two (i.e. dermatoglyphic parameters and brain structure) which share ectodermal origin and common developmental window has not been explored extensively. The current study examined dermatoglyphic correlates of hippocampal volume in antipsychotic-naïve schizophrenia patients in comparison with matched healthy controls. Ridge counts and asymmetry measures for palmar inter-digital areas (a-b, b-c, c-d) were obtained using high resolution digital scans of palms from 89 schizophrenia patients [M:F=48:41] and 48 healthy controls [M:F=30:18]. Brain scans were obtained for subset of subjects including 26 antipsychotic-naïve patients [M:F=13:13] and 29 healthy controls [M:F=19:10] using 3 T-MRI. Hippocampal volume and palmar ridge counts were measured by blinded raters with good inter-rater reliability using valid methods. Directional asymmetry (DA) of b-c and bilateral hippocampal volume were significantly lower in patients than controls. Significant positive correlation was found between DA and ridge count of b-c with bilateral anterior hippocampal volume. Study demonstrates the utility of dermatoglyphic markers in identifying structural changes in the brain which may form the basis for neurodevelopmental pathogenesis in schizophrenia.

  14. Review article: volume expansion in patients with cirrhosis

    DEFF Research Database (Denmark)

    Henriksen, Jens Henrik; Kiszka-Kanowitz, Marianne; Bendtsen, Flemming

    2002-01-01

    Adequate size and distribution of the circulating medium are important for cardiovascular function, tissue oxygenation, and fluid homoeostasis. Patients with cirrhosis have cardiovascular dysfunction with a hyperkinetic systemic circulation, abnormal distribution of the blood volume, vasodilation...

  15. Review article: volume expansion in patients with cirrhosis

    DEFF Research Database (Denmark)

    Henriksen, Jens Henrik Sahl; Kiszka-Kanowitz, Marianne; Bendtsen, Flemming

    2002-01-01

    Adequate size and distribution of the circulating medium are important for cardiovascular function, tissue oxygenation, and fluid homoeostasis. Patients with cirrhosis have cardiovascular dysfunction with a hyperkinetic systemic circulation, abnormal distribution of the blood volume, vasodilation...

  16. Plasmodium vivax infection induces expansion of activated naïve/memory T cells and differentiation into a central memory profile.

    Science.gov (United States)

    Silva, Ana Luiza Teixeira; Lacerda, Marcus Vinícius; Fujiwara, Ricardo Toshio; Bueno, Lilian Lacerda; Braga, Erika Martins

    2013-11-01

    Immunity to malaria is widely believed to wane in the absence of reinfection, but direct evidence for the presence or absence of durable immunological memory to malaria is limited. Here, we characterized the profile of circulating naïve and memory (including central and effector) CD4⁺ T cells responses of individuals naturally infected by Plasmodium vivax. In the current study, we demonstrated that acute P. vivax infection induces a significant increase in the absolute number of both naïve and memory cells, which were responsible for the production of anti-inflammatory (IL-10) and pro-inflammatory (IFN-γ) cytokines. Finally, we described the profile of memory cell subtypes (T(CM)-CD45RO(high)CCR7⁺ and T(EM)-CD45RO(high)CCR7⁻), as well as the pattern of cell migration based on CD62L selectin expression, demonstrating that P. vivax-infected donors presented with a predominantly central memory cell profile. Our results indicate that the expansion of both naïve and memory T cells, responsible for the production of both pro-inflammatory and regulatory cytokines, which might also contribute to the modulation of immune responses during P. vivax infection.

  17. Review article: volume expansion in patients with cirrhosis

    DEFF Research Database (Denmark)

    Henriksen, Jens Henrik; Kiszka-Kanowitz, Marianne; Bendtsen, Flemming

    2002-01-01

    in advanced cirrhosis is qualitatively and quantitatively different from that of healthy subjects, and in those with early cirrhosis. Timely handling is essential, but difficult as it is a balance between the risks of excess extravascular volume loading and further circulatory dysfunction in these patients...

  18. Portsmouth Gaseous Diffusion Plant expansion: final environmental statement. Volume 1

    Energy Technology Data Exchange (ETDEWEB)

    1977-09-01

    Volume 1 is comprised of chapters on: background and description; environmental impacts of add-on gaseous diffusion plant; unavoidable adverse environmental effects; alternatives; relationship between short-term uses and long-term productivity; relationship of program to land-use plans, policies, and controls; irreversible and irretrievable commitments of resources; cost-benefit analysis; and response to comment letters. (LK)

  19. Acute blood volume expansion delays the gastrointestinal transit of a charcoal meal in awake rats

    Directory of Open Access Journals (Sweden)

    de-Oliveira G.R.

    1998-01-01

    Full Text Available The present study evaluates the effect of blood volume expansion on the gastrointestinal transit of a charchoal meal (2.5 ml of an aqueous suspension consisting of 5% charcoal and 5% gum arabic in awake male Wistar rats (200-270 g. On the day before the experiments, the rats were anesthetized with ether, submitted to left jugular vein cannulation and fasted with water ad libitum until 2 h before the gastrointestinal transit measurement. Blood volume expansion by iv infusion of 1 ml/min Ringer bicarbonate in volumes of 3, 4 or 5% body weight delayed gastrointestinal transit at 10 min after test meal administration by 21.3-26.7% (P<0.05, but no effect was observed after 1 or 2% body weight expansion. The effect of blood volume expansion (up to 5% body weight on gastrointestinal transit lasted for at least 60 min (P<0.05. Mean arterial pressure increased transiently and central venous pressure increased and hematocrit decreased (P<0.05. Subdiaphragmatic vagotomy and yohimbine (3 mg/kg prevented the delay caused by expansion on gastrointestinal transit, while atropine (0.5 mg/kg, L-NAME (2 mg/kg, hexamethonium (10 mg/kg, prazosin (1 mg/kg or propranolol (2 mg/kg were ineffective. These data show that blood volume expansion delays the gastrointestinal transit of a charcoal meal and that vagal and yohimbine-sensitive pathways appear to be involved in this phenomenon. The delay in gastrointestinal transit observed here, taken together with the modifications of gastrointestinal permeability to salt and water reported by others, may be part of the mechanisms involved in liquid excess management.

  20. Does hyrax expansion therapy affect maxillary sinus volume? A cone-beam computed tomography report

    Energy Technology Data Exchange (ETDEWEB)

    Darsey, Drew M.; English, Jeryl D.; Ellis, Randy K.; Akyalcin, Sercan [School of Dentistry, University of Texas Health Science Center at Houston, Houston (United States); Kau, Chung H [School of Dentistry, University of Alabama at Birmingham, Birmingham (United States)

    2012-06-15

    The aim of this study was to investigate the initial effects of maxillary expansion therapy with Hyrax appliance and to evaluate the related changes in maxillary sinus volume. Thirty patients (20 females, 10 males; 13.8 years) requiring maxillary expansion therapy, as part of their comprehensive orthodontic treatment, were examined. Each patient had cone-beam computed tomography (CBCT) images taken before (T1) and after (T2) maxillary expansion therapy with a banded Hyrax appliance. Multiplanar slices were used to measure linear dimensions and palatal vault angle. Volumetric analysis was used to measure maxillary sinus volumes. Student t tests were used to compare the pre- and post-treatment measurements. Additionally, differences between two age groups were compared with Mann-Whitney U test. The level of significance was set at p=0.05. Comparison of pre-treatment to post-treatment variables revealed significant changes in the transverse dimension related to both maxillary skeletal and dental structures and palatal vault angle, resulting in a widened palatal vault (p<0.05). Hard palate showed no significant movement in the vertical and anteroposterior planes. Nasal cavity width increased on a mean value of 0.93 mm(SD=0.23, p<0.05). Maxillary sinus volume remained virtually stable. No significant age differences were observed in the sample. Hyrax expansion therapy did not have a significant impact on maxillary sinus volume.

  1. Blunted autonomic response to volume expansion in formerly preeclamptic women with low plasma volume.

    NARCIS (Netherlands)

    Krabbendam, I.; Courtar, D.A.; Janssen, B.J.; Aardenburg, R.; Peeters, L.L.; Spaanderman, M.E.A.

    2009-01-01

    OBJECTIVE: We hypothesize that low plasma volume in normotensive formerly preeclamptic women reflects reduced venous storage capacity. To test this hypothesis, we compared circulatory and autonomic responses to acute volume loading between women with low and those with normal plasma volume. METHODS:

  2. Effect of volume expansion on systemic hemodynamics and central and arterial blood volume in cirrhosis

    DEFF Research Database (Denmark)

    Møller, S; Bendtsen, F; Henriksen, Jens Henrik Sahl

    1995-01-01

    and in controls. METHODS: Thirty-nine patients with cirrhosis (12 patients with Child-Turcotte class A, 14 with class B, and 13 with class C) and 6 controls were studied. During hepatic vein catheterization, cardiac output, systemic vascular resistance, central and arterial blood volume, noncentral blood volume...

  3. Lack of anion effect on volume expansion natriuresis in the developing canine kidney.

    Science.gov (United States)

    Lorenz, J M; Kleinman, L I; Disney, T A

    1986-10-01

    The renal response to volume expansion with sodium chloride or sodium bicarbonate was studied in 15 newborn and 13 adult dogs. Proximal and distal nephron function were estimated using the technique of distal nephron blockade. Fractional sodium reabsorption was 99.0 +/- 0.3% in newborn and 96.6 +/- 0.06% in adult during the NaCl expansion (P less than 0.01) and 98.1 +/- 0.7% in the newborn and 93.2 +/- 0.7% in the adult during NaHCO3 expansion (P less than 0.001). With either anion the higher fractional sodium reabsorption in the newborn was due to reabsorption of a greater fraction of the load presented to the distal nephron segment. The percent of the distal sodium load that was reabsorbed was 98.0 +/- 0.6% in the newborn and 92.2 +/- 1.0% in the adult during NaCl expansion, and 96.1 +/- 1.3% in the newborn and 81.5 +/- 2.4% in the adult during NaHCO3 expansion. Differences in distal nephron chloride, potassium and bicarbonate reabsorption among the groups support the hypothesis that the enhanced distal sodium reabsorption in the newborn occurred largely in the ascending loop of Henle with NaCl expansion, while it occurred in the late distal and cortical collecting tubules with NaHCO3 expansion. There was no difference between the natriuretic responses to NaCl or NaHCO3 in the newborn (P greater than 0.20); however, the natriuretic response to NaCl was less than that to NaHCO3 in the adult (P less than 0.001). This suggests that the bulk of the sodium that escaped reabsorption in Henle's loop during NaHCO3 expansion was reabsorbed in the late distal tubule in the newborn, but not in the adult.

  4. Saline volume expansion and cardiovascular physiology: novel observations, old explanations, and new questions.

    Science.gov (United States)

    Robotham, James L

    2004-10-01

    In a clinical investigation, Kumar and coworkers reported the hemodynamic events that accompany plasma volume expansion over 3 hours in healthy adult volunteers, and found that increases in stroke volume (SV) may be related to increases in left ventricular (LV)/right ventricular (RV) end-diastolic volume, as they expected, but also to decreases in LV/RV end-systolic volume. The latter finding suggests increased contractility and/or decreased afterload, which do not fit with their perception that clinicians ascribe increases in SV to increases in end-diastolic volume based on Starling's work. Increased ejection fraction and decreased vascular resistances were also observed. The same authors recently reported novel data suggesting that reduced blood viscosity may account for the observed reduction in vascular resistances with saline volume expansion. However, the variances in preload and afterload, along with uncertainty in estimates of contractility, substantially limit their ability to define a primary mechanism to explain decreases in LV end-systolic volume. A focus on using ejection fraction to evaluate the integrated performance of the cardiovascular system is provided to broaden this analytic perspective. Sagawa and colleagues described an approach to estimate the relationship, under clinical conditions, between ventricular and arterial bed elastances (i.e. maximal ventricular systolic elastance [Emax] and maximal arterial systolic elastance [Ea]), reflecting ventricular-arterial coupling. I used the mean data provided in one of the reports from Kumar and coworkers to calculate that LV Emax decreased from 1.09 to 0.96 mmHg/ml with saline volume expansion, while Ea decreased from 1.1 to 0.97 mmHg/ml and the SV increased (i.e. the increase in mean SV was associated with a decrease in mean afterload while the mean contractility decreased). The results reported by Kumar and coworkers invite further studies in normal and critically ill patients during acute saline

  5. Evolution of colour desination semantics according to the law of expansion of semtic volume of word

    Directory of Open Access Journals (Sweden)

    С В Кезина

    2008-03-01

    Full Text Available The article is devoted to judgement of historical development of colour's names according to the law of expansion of semantic volume of a word. A basis of the concept of historical development of colour designation is made up of regulations about subject significance which forms the standard of colours designation, about ability of an eye to distinguish concrete colour and about a degree of complexity of nomination processes. The research is done on a material of Indo-European languages.

  6. Daily Suction Provided by External Volume Expansion Inducing Regeneration of Grafted Fat in a Murine Model.

    Science.gov (United States)

    Ye, Yuan; Liao, Yunjun; Lu, Feng; Gao, Jianhua

    2017-02-01

    Fat grafting has variable and sometimes poor outcomes, and therefore new methods are needed. Multiple studies have demonstrated the excellent performance of external volume expansion and focused only on preexpansion with emphasis on the recipient. Two mouse models (a suction model and a fat-exchange transplantation model) were established to investigate changes in the origins and biological behaviors of regeneration-related cells in grafted fat under daily suction provided by external volume expansion. Blood supply increased from new host-derived capillaries or macrophage infiltration under suction. CD34-positive cells showed increased migration from the host into the grafts under suction. At week 12, nearly half of the mature adipocytes regenerated in the grafts in the suction group were derived from the host. Peroxisome proliferator-activated receptor γ expression of the suction group was significantly higher than that of controls at weeks 2 and 4 during adipogenesis. The normalized sample weight of the grafted fat was significantly greater than that of controls at 1 (0.081 ± 0.001 versus 0.072 ± 0.005; p suction provided by external volume expansion favors the regeneration of grafted fat and improves retention by promoting the migration of regeneration-related cells and the differentiation of adipocytes. Thus, more mature fat tissue with a well-organized structure was formed under suction.

  7. Neuroendocrine and renal effects of intravascular volume expansion in compensated heart failure

    DEFF Research Database (Denmark)

    Gabrielsen, A; Bie, P; Holstein-Rathlou, N H

    2001-01-01

    To examine if the neuroendocrine link between volume sensing and renal function is preserved in compensated chronic heart failure [HF, ejection fraction 0.29 +/- 0.03 (mean +/- SE)] we tested the hypothesis that intravascular and central blood volume expansion by 3 h of water immersion (WI) elicits...... sustained angiotensin-converting enzyme inhibitor therapy, n = 9) absolute and fractional sodium excretion increased (P Renal free water clearance increased during WI in control subjects but not in HF......, albeit plasma vasopressin concentrations were similar in the two groups. In conclusion, the neuroendocrine link between volume sensing and renal sodium excretion is preserved in compensated HF. The natriuresis of WI is, however, modulated by the prevailing ANG II and Aldo concentrations. In contrast...

  8. Volume weighting the measure of the universe from classical slow-roll expansion

    Science.gov (United States)

    Sloan, David; Silk, Joseph

    2016-05-01

    One of the most frustrating issues in early universe cosmology centers on how to reconcile the vast choice of universes in string theory and in its most plausible high energy sibling, eternal inflation, which jointly generate the string landscape with the fine-tuned and hence relatively small number of universes that have undergone a large expansion and can accommodate observers and, in particular, galaxies. We show that such observations are highly favored for any system whereby physical parameters are distributed at a high energy scale, due to the conservation of the Liouville measure and the gauge nature of volume, asymptotically approaching a period of large isotropic expansion characterized by w =-1 . Our interpretation predicts that all observational probes for deviations from w =-1 in the foreseeable future are doomed to failure. The purpose of this paper is not to introduce a new measure for the multiverse, but rather to show how what is perhaps the most natural and well-known measure, volume weighting, arises as a consequence of the conservation of the Liouville measure on phase space during the classical slow-roll expansion.

  9. Current Injection Provokes Rapid Expansion of the Guard Cell Cytosolic Volume and Triggers Ca(2+) Signals.

    Science.gov (United States)

    Voss, Lena J; Hedrich, Rainer; Roelfsema, M Rob G

    2016-03-07

    High-resolution microscopy opens the door for detailed single-cell studies with fluorescent reporter dyes and proteins. We used a confocal spinning disc microscope to monitor fluorescent dyes and the fluorescent protein Venus in tobacco and Arabidopsis guard cells. Multi-barreled microelectrodes were used to inject dyes and apply voltage pulses, which provoke transient rises in the cytosolic Ca(2+) level. Voltage pulses also caused changes in the distribution of Lucifer Yellow and Venus, which pointed to a reversible increase of guard cell cytosolic volume. The dynamic cytosolic volume changes turned out to be provoked by current injection of ions. A reduction of the clamp current, by blocking K(+) uptake channels with Cs(+), strongly suppressed the cytosolic volume changes. Cs(+) not only inhibited the expansion of the cytosol, but also inhibited hyperpolarization-induced elevations of the cytosolic Ca(2+) concentration. A complete loss of voltage-induced Ca(2+) signals occurred when Ca(2+)-permeable plasma membrane channels were simultaneously blocked with La(3+). This shows that two mechanisms cause hyperpolarization-induced elevation of the cytosolic Ca(2+)-concentration: (i) activation of voltage-dependent Ca(2+)-permeable channels, (ii) osmotically induced expansion of the cytosol, which leads to a release of Ca(2+) from intracellular stores.

  10. Hearing Outcomes After Stereotactic Radiosurgery for Unilateral Intracanalicular Vestibular Schwannomas: Implication of Transient Volume Expansion

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Young-Hoon [Department of Neurosurgery, Seoul National University Bundang Hospital, Seongnam-si (Korea, Republic of); Department of Neurosurgery, Seoul National University College of Medicine, Seoul (Korea, Republic of); Kim, Dong Gyu, E-mail: gknife@plaza.snu.ac.kr [Department of Neurosurgery, Seoul National University Hospital, Seoul (Korea, Republic of); Department of Neurosurgery, Seoul National University College of Medicine, Seoul (Korea, Republic of); Han, Jung Ho [Department of Neurosurgery, Seoul National University Bundang Hospital, Seongnam-si (Korea, Republic of); Department of Neurosurgery, Seoul National University College of Medicine, Seoul (Korea, Republic of); Chung, Hyun-Tai; Kim, In Kyung; Song, Sang Woo [Department of Neurosurgery, Seoul National University Hospital, Seoul (Korea, Republic of); Department of Neurosurgery, Seoul National University College of Medicine, Seoul (Korea, Republic of); Park, Jeong-Hoon [Department of Neurosurgery, Seoul National University Bundang Hospital, Seongnam-si (Korea, Republic of); Department of Neurosurgery, Seoul National University College of Medicine, Seoul (Korea, Republic of); Kim, Jin Wook; Kim, Yong Hwy; Park, Chul-Kee [Department of Neurosurgery, Seoul National University Hospital, Seoul (Korea, Republic of); Department of Neurosurgery, Seoul National University College of Medicine, Seoul (Korea, Republic of); Kim, Chae-Yong [Department of Neurosurgery, Seoul National University Bundang Hospital, Seongnam-si (Korea, Republic of); Department of Neurosurgery, Seoul National University College of Medicine, Seoul (Korea, Republic of); Paek, Sun Ha; Jung, Hee-Won [Department of Neurosurgery, Seoul National University Hospital, Seoul (Korea, Republic of); Department of Neurosurgery, Seoul National University College of Medicine, Seoul (Korea, Republic of)

    2013-01-01

    Purpose: We evaluated the prognostic factors for hearing outcomes after stereotactic radiosurgery (SRS) for unilateral sporadic intracanalicular vestibular schwannomas (IC-VSs) as a clinical homogeneous group of VSs. Methods and Materials: Sixty consecutive patients with unilateral sporadic IC-VSs, defined as tumors in the internal acoustic canal, and serviceable hearing (Gardner-Roberson grade 1 or 2) were treated with SRS as an initial treatment. The mean tumor volume was 0.34 {+-} 0.03 cm{sup 3} (range, 0.03-1.00 cm{sup 3}), and the mean marginal dose was 12.2 {+-} 0.1 Gy (range, 11.5-13.0 Gy). The median follow-up duration was 62 months (range, 36-141 months). Results: The actuarial rates of serviceable hearing preservation were 70%, 63%, and 55% at 1, 2, and 5 years after SRS, respectively. In multivariate analysis, transient volume expansion of {>=}20% from initial tumor size was a statistically significant risk factor for loss of serviceable hearing and hearing deterioration (increase of pure tone average {>=}20 dB) (odds ratio = 7.638; 95% confidence interval, 2.317-25.181; P=.001 and odds ratio = 3.507; 95% confidence interval, 1.228-10.018; P=.019, respectively). The cochlear radiation dose did not reach statistical significance. Conclusions: Transient volume expansion after SRS for VSs seems to be correlated with hearing deterioration when defined properly in a clinically homogeneous group of patients.

  11. Impact of volume expansion on the efficacy and pharmacokinetics of liposome bupivacaine

    Directory of Open Access Journals (Sweden)

    Hadzic A

    2015-12-01

    Full Text Available Admir Hadzic,1,2 John A Abikhaled,3 William J Harmon4 1Department of Anesthesiology, The New York School of Regional Anesthesia (NYSORA, New York, NY, USA; 2Department of Anesthesiology, Ziekenhouse Oost Limburgh, Genk, Belgium; 3Austin Surgeons, Austin, TX, 4Urology San Antonio, San Antonio, TX, USA Abstract: Liposome bupivacaine is a prolonged-release liposomal formulation of bupivacaine indicated for single-dose infiltration into the surgical site to produce postsurgical analgesia of longer duration than traditional local anesthetics. This review summarizes the available data on how volume expansion may impact the analgesic efficacy of liposome bupivacaine. The Phase II and III clinical studies that involved surgical site administration of liposome bupivacaine at various concentrations in different surgical settings revealed no apparent concentration–efficacy relationship. A single-center, prospective study comparing the efficacy of transversus abdominis plane infiltration with liposome bupivacaine administered in a lower (266 mg/40 mL vs a higher (266 mg/20 mL dose concentration in subjects undergoing robotic-assisted laparoscopic prostatectomy also reported similar postsurgical pain intensity scores and opioid usage in both treatment groups. The pharmacokinetic profile of liposome bupivacaine following subcutaneous injections in rats was unaltered by differences in drug concentration, dose, or injection volume within the ranges tested. Volume expansion of liposome bupivacaine to a total volume of 300 mL or less does not appear to impact its clinical efficacy or pharmacokinetic profile, thus allowing flexibility to administer the formulation across a wide range of diluent volumes. Keywords: pain, analgesia, liposome bupivacaine, dose, concentration, dilution 

  12. Irreversible volume expansion of a TATB-based composite and compressive strength

    Science.gov (United States)

    Thompson, Darla Graff; Schwarz, Ricardo B.; DeLuca, Racci

    2017-01-01

    It has long been known that compacted composites containing TATB (triaminotrinitrobenzene) crystals undergo "ratchet growth," an irreversible volume expansion upon thermal cycling. A clear mechanism has not been established for this phenomenon, but is believed to arise from the highly-anisotropic CTE of TATB crystals and interactions caused by compaction. Explosive performance depends fundamentally on bulk density, so the effect may be important. PBX 9502 is a plastic bonded explosive containing 95 wt% TATB crystals. We have monitored uniaxial length changes of PBX 9502 specimens for various thermal cycles providing mechanistic insight. Post-cycled specimens were compression tested to determine if mechanical properties correlated with the detailed thermal history.

  13. Glue embolization of the giant aneurysm by reducing thrombosis-induced volume expansion effect

    Energy Technology Data Exchange (ETDEWEB)

    Yeom, Yoo Kyung; Suh, Dae Chul [Dept. of Radiology and Research Institute of Radiology, University of Ulsan College of Medicine, Asan Medical Center, Seoul (Korea, Republic of)

    2015-04-15

    A giant aneurysm due to a large intra-aneurysmal volume can be complicated by a delayed massive volume expansion caused by thrombus formation. To prevent such a severe mass effect, we obliterated the aneurysmal lumen by gluing and prevented further development of thrombosis. A 52-year-old female with a giant aneurysm at the cavernous segment of the internal carotid artery presented with tinnitus and intermittent diplopia. After confirming with a negative occlusion test, the right internal carotid artery was trapped by coiling and with further obliteration of the aneurysmal lumen by gluing. She developed a mild diplopia after the procedure and recovered without any deficit. The magnetic resonance angiography showed a stable occlusion of the aneurysm and good collateral filling of the cerebral vessel 15 months later.

  14. FINITE VOLUME METHOD FOR SIMULATION OF VISCOELASTIC FLOW THROUGH A EXPANSION CHANNEL

    Institute of Scientific and Technical Information of China (English)

    FU Chun-quan; JIANG Hai-mei; YIN Hong-jun; SU Yu-chi; ZENG Ye-ming

    2009-01-01

    A finite volume method for the numerical solution of viscoelastic flows is given. The flow of a differential Upper-Convected Maxwell (UCM) fluid through an abrupt expansion has been chosen as a prototype example. The conservation and constitutive equations are solved using the Finite Volume Method (FVM) in a staggered grid with an upwind scheme for the viscoelastic stresses and a hybrid scheme for the velocities. An enhanced-in-speed pressure-correction algorithm is used and a method for handling the source term in the momentum equations is employed. Improved accuracy is achieved by a special discretization of the boundary conditions. Stable solutions are obtained for higher Weissenberg number (We), further extending the range of simulations with the FVM. Numerical results show the viscoelasticity of polymer solutions is the main factor influencing the sweep efficiency.

  15. Analysis of volume expansion data for periclase, lime, corundum and spinel at high temperatures

    Indian Academy of Sciences (India)

    B P Singh; H Chandra; R Shyam; A Singh

    2012-08-01

    We have presented an analysis of the volume expansion data for periclase (MgO), lime (CaO), corundum (Al2O3) and spinel (MgAl2O4) determined experimentally by Fiquet et al (1999) from 300K up to 3000K. The thermal equation of state due to Suzuki et al (1979) and Shanker et al (1997) are used to study the relationships between thermal pressure and volume expansion for the entire range of temperatures starting from room temperature up to the melting temperatures of the solids under study. Comparison of the results obtained in the present study with the corresponding experimental data reveal that the thermal pressure changes with temperature almost linearly up to quite high temperatures. At extremely high temperatures close to the melting temperatures thermal pressure deviates significantly from linearity. This prediction is consistent with other recent investigations. A quantitative analysis based on the theory of anharmonic effects has been presented to account for the nonlinear variation of the thermal pressure at high temperatures.

  16. Pressure-induced volume expansion of zeolites in the natrolite family.

    Science.gov (United States)

    Lee, Yongjae; Vogt, Thomas; Hriljac, Joseph A; Parise, John B; Artioli, Gilberto

    2002-05-15

    Powder diffraction patterns of the zeolites natrolite (Na(16)Al(16)Si(24)O(80).16H(2)O), mesolite (Na(5.33)Ca(5.33)Al(16)Si(24)O(80).21.33H(2)O), scolecite (Ca(8)Al(16)Si(24)O(80).24H(2)O), and a gallosilicate analogue of natrolite (K(16)Ga(16)Si(24)O(80).12H(2)O), all crystallizing with a natrolite framework topology, were measured as a function of pressure up to 5.0 GPa with use of a diamond-anvil cell and a 200 microm focused monochromatic synchrotron X-ray beam. Under the hydrostatic conditions mediated by an alcohol and water mixture, all these materials showed an abrupt volume expansion (ca. 2.5% in natrolite) between 0.8 and 1.5 GPa without altering the framework topology. Rietveld refinements using the data collected on natrolite show that the anomalous swelling is due to the selective sorption of water from the pressure-transmission fluid expanding the channels along the a- and b-unit cell axes. This gives rise to a "superhydrated" phase of natrolite with an approximate formula of Na(16)Al(16)Si(24)O(80).32H(2)O, which contains hydrogen-bonded helical water nanotubes along the channels. In mesolite, which at ambient pressure is composed of ordered layers of sodium- and calcium-containing channels in a 1:2 ratio along the b-axis, this anomalous swelling is accompanied by a loss of the superlattice reflections (b(mesolite) = 3b(natrolite)). This suggests a pressure-induced order-disorder transition involving the motions of sodium and calcium cations either through cross-channel diffusion or within the respective channels. The powder diffraction data of scolecite, a monoclinic analogue of natrolite where all sodium cations are substituted by calcium and water molecules, reveal a reversible pressure-induced partial amorphization under hydrostatic conditions. Unlike the 2-dimensional swelling observed in natrolite and mesolite, the volume expansion of the potassium gallosilicate natrolite is 3-dimensional and includes the lengthening of the channel axis. In

  17. The effect of female volleyball players’ leg volume and mass on balance and reaction timeBayan voleybolcuların bacak hacim ve kütlesinin denge ve reaksiyon zamanına etkisi

    Directory of Open Access Journals (Sweden)

    Serkan İbiş

    2015-11-01

    Full Text Available In this study, it is aimed to investigate the relationship between leg volume - mass and balance – reaction time of the third league female volleyball players. 20 volunteer third league volleyball players, who are still active, are participated in this study. The average age of participant female volleyball players is 23,20±3,42 years, average height 176,30±7,78 cm, average weight 65.11±8,22 kg. Participant female volleyball players’ leg volume by Frustum method, leg mass by Hanavan method, static and dynamic balance by Biodex Balance System and visual reaction time by MOART Lafayette Reaction Measuring Device were measured. In analyzing the relation among the measurements, Pearson Product Moment Correlation coefficient was used. As a result of analysis of the obtained data; significant moderate correlation was found between the legs mass and dynamic balance (r=0.654, p<0,05. It was determined with a highly significant relationship between leg mass and foot volume (r=0.913, p<0,01 and foot mass (r=0.917, p<0,01. Also a significant relationship was found between leg volume and foot volume (r=0.800, p<0,01 and foot mass (r=0.644, p<0,05. Consequently; it can be said that there is a highly significant relationship between leg volume-mass and foot volume-mass, and there is a relationship between dynamic balance and leg mass of the third league female volleyball players.   Özet Bu çalışmada, üçüncü lig bayan voleybolcuların bacak hacimleri ile denge ve reaksiyon zamanları arasındaki ilişkinin incelenmesi amaçlanmıştır. Çalışmaya üçüncü ligde oynayan toplam 20 gönüllü bayan voleybolcu katılmıştır. Çalışmaya katılan bayan voleybolcuların yaş ortalamaları 23,20±3,42 yıl, boy ortalamaları 176,30±7,78 cm, ağırlık ortalamaları 65.11±8,22 kg’dır. Çalışmada katılan bayan voleybolcuların bacak hacmi Frustum yöntemi, bacak kütlesi Hanavan yöntemi, statik-dinamik denge ölçümü Biodex Denge

  18. Volume and expansivity changes of micelle formation measured by pressure perturbation calorimetry.

    Science.gov (United States)

    Fan, Helen Y; Nazari, Mozhgan; Chowdhury, Saria; Heerklotz, Heiko

    2011-03-01

    We present the application of pressure perturbation calorimetry (PPC) as a new method for the volumetric characterization of the micelle formation of surfactants. The evaluation is realized by a global fit of PPC curves at different surfactant concentration ranging, if possible, from below to far above the CMC. It is based on the knowledge of the temperature dependence of the CMC, which can for example be characterized by isothermal titration calorimetry. We demonstrate the new approach for decyl-β-maltopyranoside (DM). It shows a strong volume increase upon micelle formation of 16 ± 2.5 mL/mol (+4%) at 25 °C, and changes with temperature by -0.1 mL/(mol K). The apparent molar expansivity (E(S)) decreases upon micelle formation from 0.44 to 0.31 mL/(mol K) at 25 °C. Surprisingly, the temperature dependence of the expansivity of DM in solution (as compared with that of maltose) does not agree with the principal behavior described for polar (E(S)(T) decreasing) and hydrophobic (E(S)(T) increasing) solutes or moieties before. The results are discussed in terms of changes in hydration of the molecules and internal packing of the micelles and compared with the volumetric effects of transitions of proteins, DNA, lipids, and polymers.

  19. Molar volume, thermal expansivity and isothermal compressibility of trans-decahydronaphthalene up to 200MPa and 446K

    Institute of Scientific and Technical Information of China (English)

    Zhu Hu-Gang; Liu Zhi-Hua; Tian Yi-Ling; Xue Yuan; Yin Liang

    2005-01-01

    The molar volume isotherms of trans-decahydronaphthalene (C10H18) between 293 and 446 K and at pressures from 10 to 200 MPa have been determined. A modified Tait equation of state is used to fit each experimental molar volume isotherm with a maximum average deviation of 0.029%. The thermal expansivity (cubic expansion coefficient) α and isothermal compressibility κ were determined by fitting the slopes of the isobaric curves and isotherms, respectively.The coefficients in the equation Vm = C1 + C2T + C3T2 - C4p - C5pT have been fitted with an average deviation of 1.03%.

  20. VeVeRa-IV

    NARCIS (Netherlands)

    Evelien Eggink; Debbie Oudijk; Klarita Sadiraj

    2012-01-01

    Original title: VeVeRa-IV The Dutch population is set to age rapidly in the coming years. More and more people will also attain a very great age. This means that the need for home care and care provided in nursing or residential care homes will also increase. As part of the Long-term Care Programme

  1. Patterns of renal dopamine release to regulate diuresis and natriuresis during volume expansion. Role of renal monoamine-oxidase.

    Science.gov (United States)

    de Luca Sarobe, Verónica; Di Ciano, Luis; Carranza, Andrea M; Levin, Gloria; Arrizurieta, Elvira E; Ibarra, Fernando R

    2010-01-01

    Diuretic and natriuretic effects of renal dopamine (DA) are well established. However, in volume expansion the pattern of renal DA release into urine (UDAV) and the role of enzymes involved in DA synthesis/degradation have not yet been defined. The objective was to determine the pattern of UDAV during volume expansion and to characterize the involvement of monoamine-oxidase (MAO) and aromatic amino-acid decarboxylase (AADC) in this response. In this study male Wistar rats were expanded with NaCl 0.9% at a rate of 5% BWt per hour. At the beginning of expansion three groups received a single drug injection as follows: C (vehicle, Control), IMAO (MAO inhibitor Pargyline, 20 mg/kg BWt, i.v.) and BNZ (AADC inhibitor Benserazide, 25 mg/kg BWt, i.v.). Results revealed that in C rats UDAV (ng/30 min/100g BWt) increased in the first 30 min expansion from 11.5 +/- 1.20 to 21.8 +/- 3.10 (p diuresis and natriuresis over controls. BNZ abolished the early UDAV peak to 3.2+/-0.72 (p diuresis were diminished by BNZ treatment. Results indicate that an increment in renal DA release into urine occurs early in expansion and in a peak-shaped way. In this response MAO plays a predominant role.

  2. Plasma volume expansion does not increase maximal cardiac output or VO2 max in lowlanders acclimatized to altitude.

    Science.gov (United States)

    Calbet, José A L; Rådegran, Göran; Boushel, Robert; Søndergaard, Hans; Saltin, Bengt; Wagner, Peter D

    2004-09-01

    With altitude acclimatization, blood hemoglobin concentration increases while plasma volume (PV) and maximal cardiac output (Qmax) decrease. This investigation aimed to determine whether reduction of Qmax at altitude is due to low circulating blood volume (BV). Eight Danish lowlanders (3 females, 5 males: age 24.0 +/- 0.6 yr; mean +/- SE) performed submaximal and maximal exercise on a cycle ergometer after 9 wk at 5,260 m altitude (Mt. Chacaltaya, Bolivia). This was done first with BV resulting from acclimatization (BV = 5.40 +/- 0.39 liters) and again 2-4 days later, 1 h after PV expansion with 1 liter of 6% dextran 70 (BV = 6.32 +/- 0.34 liters). PV expansion had no effect on Qmax, maximal O2 consumption (VO2), and exercise capacity. Despite maximal systemic O2 transport being reduced 19% due to hemodilution after PV expansion, whole body VO2 was maintained by greater systemic O2 extraction (P VO2 during exercise regardless of PV. Pulmonary ventilation, gas exchange, and acid-base balance were essentially unaffected by PV expansion. Sea level Qmax and exercise capacity were restored with hyperoxia at altitude independently of BV. Low BV is not a primary cause for reduction of Qmax at altitude when acclimatized. Furthermore, hemodilution caused by PV expansion at altitude is compensated for by increased systemic O2 extraction with similar peak muscular O2 delivery, such that maximal exercise capacity is unaffected.

  3. A MODEL TO ESTIMATE VOLUME CHANGE DUE TO RADIOLYTIC GAS BUBBLES AND THERMAL EXPANSION IN SOLUTION REACTORS

    Energy Technology Data Exchange (ETDEWEB)

    F. SOUTO; A HEGER

    2001-02-01

    Aqueous homogeneous solution reactors have been proposed for the production of medical isotopes. However, the reactivity effects of fuel solution volume change, due to formation of radiolytic gas bubbles and thermal expansion, have to be mitigated to allow steady-state operation of solution reactors. The results of the free run experiments analyzed indicate that the proposed model to estimate the void volume due to radiolytic gas bubbles and thermal expansion in solution reactors can accurately describe the observed behavior during the experiments. This void volume due to radiolytic gas bubbles and fuel solution thermal expansion can then be used in the investigation of reactivity effects in fissile solutions. In addition, these experiments confirm that the radiolytic gas bubbles are formed at a higher temperature than the fuel solution temperature. These experiments also indicate that the mole-weighted average for the radiolytic gas bubbles in uranyl fluoride solutions is about 1 {micro}m. Finally, it should be noted that another model, currently under development, would simulate the power behavior during the transient given the initial fuel solution level and density. The model is based on Monte Carlo simulation with the MCNP computer code [Briesmeister, 1997] to obtain the reactor reactivity as a function of the fuel solution density, which, in turn, changes due to thermal expansion and radiolytic gas bubble formation.

  4. Extrastriatal dopamine D2/3 receptors and cortical grey matter volumes in antipsychotic-naïve schizophrenia patients before and after initial antipsychotic treatment.

    Science.gov (United States)

    Nørbak-Emig, Henrik; Pinborg, Lars H; Raghava, Jayachandra M; Svarer, Claus; Baaré, William F C; Allerup, Peter; Friberg, Lars; Rostrup, Egill; Glenthøj, Birte; Ebdrup, Bjørn H

    2017-10-01

    Long-term dopamine D2/3 receptor blockade, common to all antipsychotics, may underlie progressive brain volume changes observed in patients with chronic schizophrenia. In the present study, we examined associations between cortical volume changes and extrastriatal dopamine D2/3 receptor binding potentials (BPND) in first-episode schizophrenia patents at baseline and after antipsychotic treatment. Twenty-two initially antipsychotic-naïve patients underwent magnetic resonance imaging (MRI), [(123)I]epidepride single-photon emission computerised tomography (SPECT), and psychopathology assessments before and after 3 months of treatment with either risperidone (N = 13) or zuclopenthixol (N = 9). Twenty healthy controls matched on age, gender and parental socioeconomic status underwent baseline MRI and SPECT. Neither extrastriatal D2/3 receptor BPND at baseline, nor blockade at follow-up, was related to regional cortical volume changes. In post-hoc analyses excluding three patients with cannabis use we found that higher D2/3 receptor occupancy was significantly associated with an increase in right frontal grey matter volume. The present data do not support an association between extrastriatal D2/3 receptor blockade and extrastriatal grey matter loss in the early phases of schizophrenia. Although inconclusive, our exclusion of patients tested positive for cannabis use speaks to keeping attention to potential confounding factors in imaging studies.

  5. A model to estimate volume change due to radiolytic gas bubbles and thermal expansion in solution reactors

    Energy Technology Data Exchange (ETDEWEB)

    Souto, F.J. [NIS-6: Advanced Nuclear Technology, Los Alamos National Lab., Los Alamos, NM (United States); Heger, A.S. [ESA-EA: Engineering Sciences and Application, Los Alamos National Lab., Los Alamos, NM (United States)

    2001-07-01

    To investigate the effects of radiolytic gas bubbles and thermal expansion on the steady-state operation of solution reactors at the power level required for the production of medical isotopes, a calculational model has been developed. To validate this model, including its principal hypotheses, specific experiments at the Los Alamos National Laboratory SHEBA uranyl fluoride solution reactor were conducted. The following sections describe radiolytic gas generation in solution reactors, the equations to estimate the fuel solution volume change due to radiolytic gas bubbles and thermal expansion, the experiments conducted at SHEBA, and the comparison of experimental results and model calculations. (author)

  6. Serotoninergic Modulation of Basal Cardiovascular Responses and Responses Induced by Isotonic Extracellular Volume Expansion in Rats

    Science.gov (United States)

    Semionatto, Isadora Ferraz; Raminelli, Adrieli Oliveira; Alves, Angelica Cristina; Capitelli, Caroline Santos; Chriguer, Rosangela Soares

    2017-01-01

    Background Isotonic blood volume expansion (BVE) induced alterations of sympathetic and parasympathetic activity in the heart and blood vessels, which can be modulated by serotonergic pathways. Objective To evaluate the effect of saline or serotonergic agonist (DOI) administration in the hypothalamic paraventricular nucleus (PVN) on cardiovascular responses after BVE. Methods We recorded pulsatile blood pressure through the femoral artery to obtain the mean arterial pressure (MAP), systolic (SBP) and diastolic blood pressure (DBP), heart rate (HR) and the sympathetic-vagal ratio (LF/HF) of Wistar rats before and after they received bilateral microinjections of saline or DOI into the PVN, followed by BVE. Results No significant differences were observed in the values of the studied variables in the different treatments from the control group. However, when animals are treated with DOI followed by BVE there is a significant increase in relation to the BE control group in all the studied variables: MBP (114.42±7.85 vs 101.34±9.17); SBP (147.23±14.31 vs 129.39±10.70); DBP (98.01 ±4.91 vs 87.31±8.61); HR (421.02±43.32 vs 356.35±41.99); and LF/HF ratio (2.32±0.80 vs 0.27±0.32). Discussion The present study showed that the induction of isotonic BVE did not promote alterations in MAP, HR and LF/HF ratio. On the other hand, the injection of DOI into PVN of the hypothalamus followed by isotonic BVE resulted in a significant increase of all variables. Conclusion These results suggest that serotonin induced a neuromodulation in the PVN level, which promotes an inhibition of the baroreflex response to BVE. Therefore, the present study suggests the involvement of the serotonergic system in the modulation of vagal reflex response at PVN in the normotensive rats. PMID:28099586

  7. Plasma volume expansion does not increase maximal cardiac output or VO2 max in lowlanders acclimatized to altitude

    DEFF Research Database (Denmark)

    Calbet, José A L; Rådegran, Göran; Boushel, Robert Christopher

    2004-01-01

    With altitude acclimatization, blood hemoglobin concentration increases while plasma volume (PV) and maximal cardiac output (Qmax) decrease. This investigation aimed to determine whether reduction of Qmax at altitude is due to low circulating blood volume (BV). Eight Danish lowlanders (3 females, 5...... males: age 24.0 +/- 0.6 yr; mean +/- SE) performed submaximal and maximal exercise on a cycle ergometer after 9 wk at 5,260 m altitude (Mt. Chacaltaya, Bolivia). This was done first with BV resulting from acclimatization (BV = 5.40 +/- 0.39 liters) and again 2-4 days later, 1 h after PV expansion with 1...... level Qmax and exercise capacity were restored with hyperoxia at altitude independently of BV. Low BV is not a primary cause for reduction of Qmax at altitude when acclimatized. Furthermore, hemodilution caused by PV expansion at altitude is compensated for by increased systemic O2 extraction...

  8. Thermophysical Properties of Matter - the TPRC Data Series. Volume 13. Thermal Expansion - Nonmetallic Solids

    Science.gov (United States)

    1977-01-01

    Amer. Dental Assoc., 20, 108-19, 1933. 267 52429 Nielsen, T. H. and Leipold, M. H., "Thermal Expansion of Yttria-Stpbilized Zirconia , "J. Amer. Ceram...isotropic the coefficient of thermal Symmetres expansion is equal to three times the coefficient of linear thermal expansion; i.e., Cubic at a, a1 0 0 0...can Where sj (j = 4, 5, 6) = 0, as in cubic , hexagonal, happen in open-structure crystals, such as silicon orthorhombic, and some tetragonal crystals, a

  9. Serotoninergic Modulation of Basal Cardiovascular Responses and Responses Induced by Isotonic Extracellular Volume Expansion in Rats

    Directory of Open Access Journals (Sweden)

    Isadora Ferraz Semionatto

    Full Text Available Abstract Background: Isotonic blood volume expansion (BVE induced alterations of sympathetic and parasympathetic activity in the heart and blood vessels, which can be modulated by serotonergic pathways. Objective: To evaluate the effect of saline or serotonergic agonist (DOI administration in the hypothalamic paraventricular nucleus (PVN on cardiovascular responses after BVE. Methods: We recorded pulsatile blood pressure through the femoral artery to obtain the mean arterial pressure (MAP, systolic (SBP and diastolic blood pressure (DBP, heart rate (HR and the sympathetic-vagal ratio (LF/HF of Wistar rats before and after they received bilateral microinjections of saline or DOI into the PVN, followed by BVE. Results: No significant differences were observed in the values of the studied variables in the different treatments from the control group. However, when animals are treated with DOI followed by BVE there is a significant increase in relation to the BE control group in all the studied variables: MBP (114.42±7.85 vs 101.34±9.17; SBP (147.23±14.31 vs 129.39±10.70; DBP (98.01 ±4.91 vs 87.31±8.61; HR (421.02±43.32 vs 356.35±41.99; and LF/HF ratio (2.32±0.80 vs 0.27±0.32. Discussion: The present study showed that the induction of isotonic BVE did not promote alterations in MAP, HR and LF/HF ratio. On the other hand, the injection of DOI into PVN of the hypothalamus followed by isotonic BVE resulted in a significant increase of all variables. Conclusion: These results suggest that serotonin induced a neuromodulation in the PVN level, which promotes an inhibition of the baroreflex response to BVE. Therefore, the present study suggests the involvement of the serotonergic system in the modulation of vagal reflex response at PVN in the normotensive rats.

  10. Modelos de geração e variabilidade no volume diário de veículos em shopping centers

    Directory of Open Access Journals (Sweden)

    André Cadamartori Jacobsen

    2010-11-01

    Full Text Available

    Resumo: Os modelos de geração de viagens, utilizados nos Estudos de Impacto de Tráfego (EIT de shopping centers, geralmente estimam volumes diários médios anuais de veículos atraídos. Neste artigo são confrontados os volumes estimados por modelos referenciados na literatura com volumes veiculares observados em seis empreendimentos localizados na região metropolitana de Porto Alegre. Quando comparadas com as distribuições de volumes diários de cada shopping center, as estimativas revelam erros expressivos. Modelos baseados apenas na Área Bruta Locável (ABL mostram-se incapazes de representar as diferenças entre os empreendimentos, indicando a necessidade da incorporação de novas variáveis explicativas. Entende-se que as diferenças entre estimativas e valores observados estejam fortemente associadas ao poder aquisitivo dos clientes. O artigo propõe modelos não-convencionais de geração de viagens construídos com os dados dos shopping centers estudados. Entre os modelos estimados, o que incorpora a variável "valor do aluguel" das lojas dos empreendimentos resultou nos menores erros de estimativa.

    Abstract: Trip generation models, applied in Traffic Impact Studies of shopping centers, usually estimate annual average daily volumes of attracted private vehicles. In this paper we confront volumes estimated by models referred in the literature with observed vehicular volumes of six shopping centers located within the Metropolitan Area of Porto Alegre, Brazil. When compared to the distributions of daily volumes of each shopping center, estimates reveal expressive errors. Models based only on gross leasing areas are unable to represent the differences between the shopping centers, suggesting the need to incorporate new explanatory variables. We understand that the differences between estimated and observed values are strongly associated to the income of the

  11. Review of methods for predicting in situ volume change movement of expansive soil over time

    OpenAIRE

    Hana H. Adem; Sai K. Vanapalli

    2015-01-01

    The soil movement information over time is required for the design of foundations placed in expansive soils. This information is also helpful for the assessment of pre-wetting and controlled wetting mitigation alternatives for expansive soils. Several researchers during the past fifteen years have proposed different methods for the prediction of the soil movements over time. The available methods can be categorized into (i) consolidation theory-based methods, (ii) water content-based methods,...

  12. Plasma volume expansion by albumin in cirrhosis. Relation to blood volume distribution, arterial compliance and severity of disease

    DEFF Research Database (Denmark)

    Brinch, Kim; Bendtsen, Flemming; Becker, Povl Ulrik;

    2003-01-01

    BACKGROUND/AIMS: The aim of the study was to investigate the effect of a standard albumin load on blood volume distribution, arterial compliance, and the renin-angiotensin-aldosterone system in patients with different degrees of cirrhosis. METHODS: 31 patients with cirrhosis (Child classes A/B/C=...... effective arterial blood volume of such patients, which may be important in the prevention of circulatory dysfunction....

  13. Comparison of volume and diameter measurement in assessing small abdominal aortic aneurysm expansion examined using computed tomographic angiography

    Energy Technology Data Exchange (ETDEWEB)

    Parr, Adam; Jayaratne, Chanaka; Buttner, Petra [Vascular Biology Unit, James Cook University, Townsville, Queensland 4811 (Australia); Golledge, Jonathan, E-mail: Jonathan.Golledge@jcu.edu.au [Vascular Biology Unit, James Cook University, Townsville, Queensland 4811 (Australia)

    2011-07-15

    Aim: First we aimed to assess the reproducibility of a computer tomography angiography (CTA) based technique for measuring infra-renal aortic volume and diameter. Second we sought to investigate whether changes in aortic volume and diameter were similar during follow-up. Materials and methods: A prospective series of 57 patients, with aortic diameter initially measuring between 25 and 55 mm, were assessed with 2 CTAs a median of 14 months apart. Aortic volume and maximum diameter (both axial and orthogonal) were measured by a semi-automated workstation protocol based on previously defined techniques. Intra- and inter-observer reproducibility were assessed by repeat assessment of the initial CTA images of the first 33 patients included in the study, in order to estimate the 95% limits of agreements. Changes in aortic dimensions between the first and follow-up CTA, were defined for volume and diameter separately as changes greater than their respective 95% limits of agreement. Results: Reproducibility of aortic volume and diameter was excellent with an average coefficient of variation <4%. The median (inter-quartile range) increases in total volume, orthogonal and axial diameters were 4.9 cm{sup 3} (0.01-14.18), 1.2 mm (0.40-3.50) and 1.4 mm (-0.15 to 3.55) respectively. Forty-two percent of patients who had increased aortic volume above the 95% limit of agreement did not display corresponding axial or orthogonal diameter changes. Conclusions: Infra-renal total aortic volume, axial and orthogonal diameter can all be measured reproducibly from CTA. Aortic volume changes are not always reflected by similar changes in diameter and therefore provide complementary information when assessing AAA expansion over time.

  14. Review of methods for predicting in situ volume change movement of expansive soil over time

    Directory of Open Access Journals (Sweden)

    Hana H. Adem

    2015-02-01

    Full Text Available The soil movement information over time is required for the design of foundations placed in expansive soils. This information is also helpful for the assessment of pre-wetting and controlled wetting mitigation alternatives for expansive soils. Several researchers during the past fifteen years have proposed different methods for the prediction of the soil movements over time. The available methods can be categorized into (i consolidation theory-based methods, (ii water content-based methods, and (iii suction-based methods. In this paper, a state-of-the-art of the prediction methods is succinctly summarized. The methods are critically reviewed in terms of their predictive capacity along with their strengths and limitations. The review highlights the need for prediction methods that are conceptually simple yet efficient for use in conventional engineering practice for different types of expansive soils.

  15. Review of methods for predicting in situ volume change movement of expansive soil over time

    Institute of Scientific and Technical Information of China (English)

    Hana H. Adem; Sai K. Vanapalli

    2015-01-01

    The soil movement information over time is required for the design of foundations placed in expansive soils. This information is also helpful for the assessment of pre-wetting and controlled wetting mitigation alternatives for expansive soils. Several researchers during the past fifteen years have proposed different methods for the prediction of the soil movements over time. The available methods can be categorized into (i) consolidation theory-based methods, (ii) water content-based methods, and (iii) suction-based methods. In this paper, a state-of-the-art of the prediction methods is succinctly summarized. The methods are critically reviewed in terms of their predictive capacity along with their strengths and limitations. The review highlights the need for prediction methods that are conceptually simple yet efficient for use in conventional engineering practice for different types of expansive soils.

  16. Modelling the thermo-mechanical volume change behaviour of compacted expansive clays

    CERN Document Server

    Tang, Anh-Minh; 10.1680/geot.2009.59.3.185

    2009-01-01

    Compacted expansive clays are often considered as a possible buffer material in high-level deep radioactive waste disposals. After the installation of waste canisters, the engineered clay barriers are subjected to thermo-hydro-mechanical actions in the form of water infiltration from the geological barrier, heat dissipation from the radioactive waste canisters, and stresses generated by clay swelling under almost confined conditions. The aim of the present work is to develop a constitutive model that is able to describe the behaviour of compacted expansive clays under these coupled thermo-hydro-mechanical actions. The proposed model is based on two existing models: one for the hydro-mechanical behaviour of compacted expansive clays and another for the thermo-mechanical behaviour of saturated clays. The elaborated model has been validated using the thermo-hydro-mechanical test results on the compacted MX80 bentonite. Comparison between the model prediction and the experimental data show that this model is able...

  17. Chemical similarity between historical and novel host plants promotes range and host expansion of the mountain pine beetle in a naïve host ecosystem.

    Science.gov (United States)

    Erbilgin, Nadir; Ma, Cary; Whitehouse, Caroline; Shan, Bin; Najar, Ahmed; Evenden, Maya

    2014-02-01

    Host plant secondary chemistry can have cascading impacts on host and range expansion of herbivorous insect populations. We investigated the role of host secondary compounds on pheromone production by the mountain pine beetle (Dendroctonus ponderosae) (MPB) and beetle attraction in response to a historical (lodgepole pine, Pinus contorta var. latifolia) and a novel (jack pine, Pinus banksiana) hosts, as pheromones regulate the host colonization process. Beetles emit the same pheromones from both hosts, but more trans-verbenol, the primary aggregation pheromone, was emitted by female beetles on the novel host. The phloem of the novel host contains more α-pinene, a secondary compound that is the precursor for trans-verbenol production in beetle, than the historical host. Beetle-induced emission of 3-carene, another secondary compound found in both hosts, was also higher from the novel host. Field tests showed that the addition of 3-carene to the pheromone mixture mimicking the aggregation pheromones produced from the two host species increased beetle capture. We conclude that chemical similarity between historical and novel hosts has facilitated host expansion of MPB in jack pine forests through the exploitation of common host secondary compounds for pheromone production and aggregation on the hosts. Furthermore, broods emerging from the novel host were larger in terms of body size.

  18. Vasopressor Agents without Volume Expansion as a Safe Alternative to Venovenous bypass during Cavaplasty Liver Transplantation

    Institute of Scientific and Technical Information of China (English)

    WU You-min; Tanyal Oyos; Rou-Yee Chenhsu; Daniel A Katz; Johnny E Brian; Stephen C Rayhill

    2004-01-01

    @@ Background Cavaplasty orthotopic liver transplan-tation (OLT)offers advantages for hepatectomy and implantation and eliminates the risk of outflow ob-struction. However, it does require clamping of the cava. This study describes the use of a vasopressor without fluid expansion or venovenous bypass ( VB ) for hemodynamic control during the andhepatic phase.

  19. Serotoninergic Modulation of Basal Cardiovascular Responses and Responses Induced by Isotonic Extracellular Volume Expansion in Rats.

    Science.gov (United States)

    Semionatto, Isadora Ferraz; Raminelli, Adrieli Oliveira; Alves, Angelica Cristina; Capitelli, Caroline Santos; Chriguer, Rosangela Soares

    2017-02-01

    Isotonic blood volume expansion (BVE) induced alterations of sympathetic and parasympathetic activity in the heart and blood vessels, which can be modulated by serotonergic pathways. To evaluate the effect of saline or serotonergic agonist (DOI) administration in the hypothalamic paraventricular nucleus (PVN) on cardiovascular responses after BVE. We recorded pulsatile blood pressure through the femoral artery to obtain the mean arterial pressure (MAP), systolic (SBP) and diastolic blood pressure (DBP), heart rate (HR) and the sympathetic-vagal ratio (LF/HF) of Wistar rats before and after they received bilateral microinjections of saline or DOI into the PVN, followed by BVE. No significant differences were observed in the values of the studied variables in the different treatments from the control group. However, when animals are treated with DOI followed by BVE there is a significant increase in relation to the BE control group in all the studied variables: MBP (114.42±7.85 vs 101.34±9.17); SBP (147.23±14.31 vs 129.39±10.70); DBP (98.01 ±4.91 vs 87.31±8.61); HR (421.02±43.32 vs 356.35±41.99); and LF/HF ratio (2.32±0.80 vs 0.27±0.32). The present study showed that the induction of isotonic BVE did not promote alterations in MAP, HR and LF/HF ratio. On the other hand, the injection of DOI into PVN of the hypothalamus followed by isotonic BVE resulted in a significant increase of all variables. These results suggest that serotonin induced a neuromodulation in the PVN level, which promotes an inhibition of the baroreflex response to BVE. Therefore, the present study suggests the involvement of the serotonergic system in the modulation of vagal reflex response at PVN in the normotensive rats. Expansão de volume extracelular (EVEC) promove alterações da atividade simpática e parassimpática no coração e vasos sanguíneos, os quais podem ser moduladas por vias serotoninérgicas. Avaliar o efeito da administração de salina ou agonista serotonin

  20. Local control of emission energy of semiconductor quantum dots using volume expansion of a phase-change material

    Science.gov (United States)

    Takahashi, Motoki; Syafawati Humam, Nurrul; Tsumori, Nobuhiro; Saiki, Toshiharu; Regreny, Philippe; Gendry, Michel

    2013-03-01

    A method is proposed to precisely control the emission energy of semiconductor quantum dots (QDs) by the application of local strain due to volume expansion of a phase-change material (GeSbTe) upon amorphization. The feasibility of the method is experimentally demonstrated using photoluminescence (PL) spectroscopy of single InAs/InP QDs on which a GeSbTe thin film is deposited. A significant red-shift of the PL peak energy upon amorphization and subsequent recovery by recrystallization with laser annealing were observed.

  1. Molar volume, thermal expansion, and bulk modulus in liquid Fe-Ni alloys at 1 bar: Evidence for magnetic anomalies?

    Science.gov (United States)

    Nasch, P. M.; Manghnani, M. H.

    New experimental data on the molar volume Ω, thermal expansion coefficient α, and ultrasonic sound velocity vp in liquid Fe-Ni systems at temperatures between melting and 1975 K are reported. The molar volume and thermal expansion data were acquired using a penetrating γ radiation method; the sound velocity data were obtained by ultrasonic interferometry. In the temperature range of this study, the molar volume Ω increases and the sound velocity vp decreases, both linearly with temperature. The adiabatic bulk modulus KS ∝ v2p/Ωp of liquid Fe-Ni alloys is nearly independent of composition at Fe content greater than 65 wt%. The temperature derivative ∂K/∂T of both adiabatic and isothermal bulk modulus of pure liquid Fe decreases by approximately 50% upon being alloyed with 15 wt% Ni. The mixing behavior of thermodynamic and cohesive properties of liquid Fe-Ni is interpreted as resulting from the existence of disordered and localized magnetic states and correlations in the liquid state, i.e., well above the Curie temperature and extending from pure Fe into the Fe-Ni stability field. These magnetic contributions have strong mechanical effects on the structure in modifying the volume and elastic modulus by as much as 13% and 31%, respectively, in the case of pure liquid Fe. It is believed that the magnetic contribution, which is likely to be absent at core temperatures, should be removed from the measured 1-bar values of density and elastic moduli if these latter were to be used as precise anchoring points in high pressure-temperature EOS.

  2. The effect of metallic coatings and crystallinity on the volume expansion of silicon during electrochemical lithiation/delithiation

    KAUST Repository

    McDowell, Matthew T.

    2012-05-01

    Applying surface coatings to alloying anodes for Li-ion batteries can improve rate capability and cycle life, but it is unclear how this second phase affects mechanical deformation during electrochemical reaction. Here, in-situ transmission electron microscopy is employed to investigate the electrochemical lithiation and delithiation of silicon nanowires (NWs) with copper coatings. When copper is coated on only one sidewall, the NW bilayer structure bends during delithiation due to length changes in the silicon. Tensile hoop stress causes conformal copper coatings to fracture during lithiation without undergoing bending deformation. In addition, in-situ and ex-situ observations indicate that a copper coating plays a role in suppressing volume expansion during lithiation. Finally, the deformation characteristics and dimensional changes of amorphous, polycrystalline, and single-crystalline silicon are compared and related to observed electrochemical behavior. This study reveals important aspects of the deformation process of silicon anodes, and the results suggest that metallic coatings can be used to improve rate behavior and to manage or direct volume expansion in optimized silicon anode frameworks. © 2012 Elsevier Ltd.

  3. Effect of suction change on water content and total volume of an expansive clay

    Institute of Scientific and Technical Information of China (English)

    ZHAN Liang-tong; CHEN Ping; NG C.W.W.

    2007-01-01

    A laboratory study was carried out on both natural and compacted specimens to investigate the complex soil-water interaction in an unsaturated expansive clay. The laboratory study includes the measurement of soil-water characteristic curves, 1D free swelling tests, measurement of swelling pressure and shrinkage tests. The test results revealed that the air-entry value of the natural specimen was quite low due to cracks and fissures present. The hydraulic hysteresis of the natural specimen was relatively insignificant as compared with the compacted specimen. Within a suction range 0 to 500 kPa, a bilinear relationship between free swelling strain (or swelling pressure) and initial soil suction was observed for both the natural and compacted specimens. As a result of over-consolidation and secondary structures such as cementation and cracks, the natural specimens exhibited significant lower swelling (or swelling pressure) than the compacted specimen. The change of matric suction exerts a more significant effect on the water phase than on the soil skeleton for this expansive clay.

  4. Portsmouth Gaseous Diffusion Plant expansion: final environmental statement. Volume 2. Appendices. [Appendices only

    Energy Technology Data Exchange (ETDEWEB)

    Liverman, James L.

    1977-09-01

    Volume 2 is comprised of appendices: Portsmouth Gaseous Diffusion Plant Existing Facilities; Ecology; Civic Involvement; Social Analysis; Population Projections; Toxicity of Air Pollutants to Biota at Portsmouth Gaseous Diffusion Plant; and Assessment of Noise Effects of an Add-On to the Portsmouth Gaseous Diffusion Plant. (LK)

  5. Peripheral Lymphoid Volume Expansion and Maintenance Are Controlled by Gut Microbiota via RALDH+ Dendritic Cells.

    Science.gov (United States)

    Zhang, Zongde; Li, Jianjian; Zheng, Wencheng; Zhao, Guang; Zhang, Hong; Wang, Xiaofei; Guo, Yaqian; Qin, Chuan; Shi, Yan

    2016-02-16

    Lymphocyte homing to draining lymph nodes is critical for the initiation of immune responses. Secondary lymphoid organs of germ-free mice are underdeveloped. How gut commensal microbes remotely regulate cellularity and volume of secondary lymphoid organs remains unknown. We report here that, driven by commensal fungi, a wave of CD45(+)CD103(+)RALDH(+) cells migrates to the peripheral lymph nodes after birth. The arrival of these cells introduces high amounts of retinoic acid, mediates the neonatal to adult addressin switch on endothelial cells, and directs the homing of lymphocytes to both gut-associated lymphoid tissues and peripheral lymph nodes. In adult mice, a small number of these RALDH(+) cells might serve to maintain the volume of secondary lymphoid organs. Homing deficiency of these cells was associated with lymph node attrition in vitamin-A-deficient mice, suggesting a perpetual dependence on retinoic acid signaling for structural and functional maintenance of peripheral immune organs.

  6. Clinical comparison between HeartMate VE auto-mode and HeartMate XVE auto-mode with Opti-Fill and the effect of stroke volume on blood chamber and inflow valve peak pressures.

    Science.gov (United States)

    Rodermans, Ben F M; Lahpor, Jaap R; van Schelven, Leonard J; Nieuwenhuis, Esther; Sukkel, Eveline Y; van Schouwen-van Kranen, Else

    2007-01-01

    We determined the difference between HeartMate (HM) VE auto mode, average filling 76 mL, and HM XVE Opti-Fill, average filling 79 mL, regarding blood chamber and inflow valve peak pressure pulses (BCPP and IVPP). The relation between stroke volume (SV) and peak pressures was investigated by using a circulatory mock loop. At high SVs, 79 to 83 mL, BCPP and IVPP never exceeded 400 mm Hg. For lower SVs, down to 50 mL, the peak pressures increased to 788 mm Hg for BCPP and 416 mm Hg for IVPP. Distribution of SV was measured in 2 VE and 6 XVE patients during rest and activities of daily living (ADL). For clinical comparison, percentages of SV >78 mL were determined. At rest, 2190 (VE) and 5772 (XVE) pump beats were registered and 4511 (VE) and 8713 (XVE) during ADL. Percentages of "SV >78 mL" at rest, respectively, were 42.5 +/- 3.5 and 78.2 +/- 4.7 (p 78 mL and makes an important contribution to reducing the incidence of high peak pressures in the clinical setting.

  7. Placental Underperfusion in a Rat Model of Intrauterine Growth Restriction Induced by a Reduced Plasma Volume Expansion.

    Directory of Open Access Journals (Sweden)

    Karine Bibeau

    Full Text Available Lower maternal plasma volume expansion was found in idiopathic intrauterine growth restriction (IUGR but the link remains to be elucidated. An animal model of IUGR was developed by giving a low-sodium diet to rats over the last week of gestation. This treatment prevents full expansion of maternal circulating volume and the increase in uterine artery diameter, leading to reduced placental weight compared to normal gestation. We aimed to verify whether this is associated with reduced remodeling of uteroplacental circulation and placental hypoxia. Dams were divided into two groups: IUGR group and normal-fed controls. Blood velocity waveforms in the main uterine artery were obtained by Doppler sonography on days 14, 18 and 21 of pregnancy. On day 22 (term = 23 days, rats were sacrificed and placentas and uterine radial arteries were collected. Diameter and myogenic response of uterine arteries supplying placentas were determined while expression of hypoxia-modulated genes (HIF-1α, VEGFA and VEGFR2, apoptotic enzyme (Caspase -3 and -9 and glycogen cells clusters were measured in control and IUGR term-placentas. In the IUGR group, impaired blood velocity in the main uterine artery along with increased resistance index was observed without alteration in umbilical artery blood velocity. Radial uterine artery diameter was reduced while myogenic response was increased. IUGR placentas displayed increased expression of hypoxia markers without change in the caspases and increased glycogen cells in the junctional zone. The present data suggest that reduced placental and fetal growth in our IUGR model may be mediated, in part, through reduced maternal uteroplacental blood flow and increased placental hypoxia.

  8. Disruption of the endothelin A receptor in the nephron causes mild fluid volume expansion

    Directory of Open Access Journals (Sweden)

    Stuart Deborah

    2012-12-01

    Full Text Available Abstract Background Endothelin, via endothelin A receptors (ETA, exerts multiple pathologic effects that contribute to disease pathogenesis throughout the body. ETA antagonists ameliorate many experimental diseases and have been extensively utilized in clinical trials. The utility of ETA blockers has been greatly limited, however, by fluid retention, sometimes leading to heart failure or death. To begin to examine this issue, the effect of genetic disruption of ETA in the nephron on blood pressure and salt handling was determined. Methods Mice were generated with doxycycline-inducible nephron-specific ETA deletion using Pax8-rtTA and LC-1 transgenes on the background of homozygous loxP-flanked ETA alleles. Arterial pressure, Na metabolism and measures of body fluid volume status (hematocrit and impedance plethysmography were assessed. Results Absence of nephron ETA did not alter arterial pressure whether mice were ingesting a normal or high Na diet. Nephron ETA disruption did not detectably affect 24 hr Na excretion or urine volume regardless of Na intake. However, mice with nephron ETA knockout that were fed a high Na diet had mild fluid retention as evidenced by an increase in body weight and a fall in hematocrit. Conclusions Genetic deletion of nephron ETA causes very modest fluid retention that does not alter arterial pressure. Nephron ETA, under normal conditions, likely do not play a major role in regulation of Na excretion or systemic hemodynamics.

  9. Influence of anodization parameters on the volume expansion of anodic aluminum oxide formed in mixed solution of phosphoric and oxalic acids

    Science.gov (United States)

    Kao, Tzung-Ta; Chang, Yao-Chung

    2014-01-01

    The growth of anodic alumina oxide was conducted in the mixed solution of phosphoric and oxalic acids. The influence of anodizing voltage, electrolyte temperature, and concentration of phosphoric and oxalic acids on the volume expansion of anodic aluminum oxide has been investigated. Either anodizing parameter is chosen to its full extent of range that allows the anodization process to be conducted without electric breakdown and to explore the highest possible volume expansion factor. The volume expansion factors were found to vary between 1.25 and 1.9 depending on the anodizing parameters. The variation is explained in connection with electric field, ion transport number, temperature effect, concentration, and activity of acids. The formation of anodic porous alumina at anodizing voltage 160 V in 1.1 M phosphoric acid mixed with 0.14 M oxalic acid at 2 °C showed the peak volume expansion factor of 1.9 and the corresponding moderate growth rate of 168 nm/min.

  10. The impact of maternal plasma volume expansion and antihypertensive treatment with intravenous dihydralazine on fetal and maternal hemodynamics during pre-eclampsia: a clinical, echo-Doppler and viscometric study.

    NARCIS (Netherlands)

    Boito, S.M.; Struijk, P.C.; Pop, G.A.M.; Visser, W. de; Steegers, E.A.P.; Wladimiroff, J.W.

    2004-01-01

    OBJECTIVES: To establish the effects of plasma volume expansion (PVE) followed by intravenous dihydralazine (DH) administration on maternal whole blood viscosity (WBV) and hematocrit, uteroplacental and fetoplacental downstream impedance and umbilical venous (UV) volume flow in pre-eclampsia. METHOD

  11. Influence of volume expansion on NaC1 reabsorption in the diluting segments of the nephron: a study using clearance methods.

    Science.gov (United States)

    Danovitch, G M; Bricker, N S

    1976-09-01

    Whether volume expansion influences NaC1 reabsorption by the diluting segment of the nephron remains a matter of controversy. In the present studies this question has been examined in normal unanesthetized dogs, undergoing maximal water diuresis. Free water clearance (CH2O/GFR) has been used as the index of NaC1 reabsorption in the diluting segment. Three expressions have been employed for "distal delivery" of NaC1: a) V/GFR, designated as the "volume term"; b) (CNa/GFR + CH2O/GFR), the "sodium term;" and c) (CC1/GFR + CH2O/GFR), the "chloride term". The validity of these terms is discussed. Three techniques were used to increase distal delivery: 1) the administration of acetazolamide to dogs in which extracellular fluid (ECF) volume was not expanded (grop 1); 2) "moderate" volume expansion (group 2); and 3) "marked" volume expansion (group 3). CH2O/GFR increased progressively with rising values for "distal delivery" regardless of which term was used to calculate the latter. With all three delivery terms, differences in distal NaC1 reabsorption emerged between the two volume-expanded groups, though only with the "chloride" term did substantial differences also emerge between the nonexpanded group 1 dogs and both volume-expanded groups. In group 1, values for CH2O/GFR increased in close to a linear fashion up to distal delivery values equal to 24% of the volume of glomerular filtrate. However, at high rates of distal delivery the rate of rise of CH2O/GFR was less in group 2 than in group 1 and the depression of values was even greater in group 3. Within the limits of the techniques used, the data suggest that volume expansion inhibits fractional NaC1 reabsorption in the diluting segment of the nephron in a dose-related fashion. The "chloride" term was found to be superior to the "volume" and "sodium" terms in revealing these changes.

  12. Effect of volume expansion with 6% hydroxyethyl starch on perioperative hemodynamics and inflammatory factors in patients with traumatic brain injury

    Institute of Scientific and Technical Information of China (English)

    Guo-Wen Zhao; Xing-Chang Zhao; Yong-Guo Cui; De-Chao Lu; Jian-Feng Wang

    2016-01-01

    Objective:To study the effect of volume expansion with 6% hydroxyethyl starch on perioperative hemodynamics and inflammatory factors in patients with traumatic brain injury. Methods:A total of 82 cases of traumatic brain injury from January 2011 to June 2016 in our hospital were randomly divided into the observation group with injection of 6% hydroxyethyl starch and the control group with injection of compound sodium lactate, 41 cases in each group. Hemodynamics, TNF-α and IL-6 were detected in before induction of anesthesia (T0), before skull plate (T1), after skull plate 5 min (T2), 15 min (T3), 30 min (T4).Results:There were no significant differences in CVP, MAP and HR between the two groups at T0 time (P>0.05); HR of the two groups of patients were significantly increased (P0.05); The MAP of the two groups began to decrease significantly at T1, but the observation group was significantly lower than the control group (P0.05). There was no significant difference in the levels of IL-6 and TNF-α between the two groups before surgery (P>0.05); After operation, the control group of TNF- and IL-6 were significantly higher, and higher than the same period of observation group, the difference was statistically significant (P<0.05).Conclusions:Using 6% hydroxyethyl starch preloading craniocerebral trauma patients is helpful to maintain the perioperative hemodynamic stability, reduce the level of inflammatory factors, which is worthy of reference.

  13. Airway surface liquid volume expansion induces rapid changes in amiloride-sensitive Na+ transport across upper airway epithelium-Implications concerning the resolution of pulmonary edema

    Science.gov (United States)

    Azizi, Fouad; Arredouani, Abdelilah; Mohammad, Ramzi M

    2015-01-01

    During airway inflammation, airway surface liquid volume (ASLV) expansion may result from the movement of plasma proteins and excess liquid into the airway lumen due to extravasation and elevation of subepithelial hydrostatic pressure. We previously demonstrated that elevation of submucosal hydrostatic pressure increases airway epithelium permeability resulting in ASLV expansion by 500 μL cm−2 h−1. Liquid reabsorption by healthy airway epithelium is regulated by active Na+ transport at a rate of 5 μL cm−2 h−1. Thus, during inflammation the airway epithelium may be submerged by a large volume of luminal liquid. Here, we have investigated the mechanism by which ASLV expansion alters active epithelial Na+ transport, and we have characterized the time course of the change. We used primary cultures of tracheal airway epithelium maintained under air interface (basal ASLV, depth is 7 ± 0.5 μm). To mimic airway flooding, ASLV was expanded to a depth of 5 mm. On switching from basal to expanded ASLV conditions, short-circuit current (Isc, a measure of total transepithelial active ion transport) declined by 90% with a half-time (t1/2) of 1 h. 24 h after the switch, there was no significant change in ATP concentration nor in the number of functional sodium pumps as revealed by [3H]-ouabain binding. However, amiloride-sensitive uptake of 22Na+ was reduced by 70% upon ASLV expansion. This process is reversible since after returning cells back to air interface, Isc recovered with a t1/2 of 5–10 h. These results may have important clinical implications concerning the development of Na+ channels activators and resolution of pulmonary edema. PMID:26333829

  14. Negative thermal expansion and spontaneous volume magnetostriction of Tb{sub 2}Fe{sub 16}Cr compound

    Energy Technology Data Exchange (ETDEWEB)

    Hao Yanming [Department of Physics, Tianjin Normal University, Tianjin 300074 (China)]. E-mail: zhao.miao@126.com; Zhao Miao [Department of Physics, Tianjin Normal University, Tianjin 300074 (China); Zhou Yan [Department of Physics, Tianjin Normal University, Tianjin 300074 (China); Hu Jifan [Department of Physics, Shandong University, Jinan, 250100 (China)

    2005-08-15

    The compound Tb{sub 2}Fe{sub 16}Cr has a hexagonal Th{sub 2}Ni{sub 17}-type structure. Negative thermal expansion was found at 292-556 K. Magnetization measurements show that a Cr atom substituting for a Fe atom increases the Curie temperature of the Tb{sub 2}Fe{sub 17} compound.

  15. Extrastriatal dopamine D2/3 receptors and cortical grey matter volumes in antipsychotic-naïve schizophrenia patients before and after initial antipsychotic treatment

    DEFF Research Database (Denmark)

    Nørbak-Emig, Henrik; Pinborg, Lars H; Raghava, Jayachandra M

    2017-01-01

    blockade at follow-up, was related to regional cortical volume changes. In post-hoc analyses excluding three patients with cannabis use we found that higher D2/3 receptor occupancy was significantly associated with an increase in right frontal grey matter volume. CONCLUSIONS: The present data do...... not support an association between extrastriatal D2/3 receptor blockade and extrastriatal grey matter loss in the early phases of schizophrenia. Although inconclusive, our exclusion of patients tested positive for cannabis use speaks to keeping attention to potential confounding factors in imaging studies....

  16. Thermal expansion of glassy polymers.

    Science.gov (United States)

    Davy, K W; Braden, M

    1992-01-01

    The thermal expansion of a number of glassy polymers of interest in dentistry has been studied using a quartz dilatometer. In some cases, the expansion was linear and therefore the coefficient of thermal expansion readily determined. Other polymers exhibited non-linear behaviour and values appropriate to different temperature ranges are quoted. The linear coefficient of thermal expansion was, to a first approximation, a function of both the molar volume and van der Waal's volume of the repeating unit.

  17. Expansion of radiofrequency ablation volume by saturated NaCl saline injection in the area of vaporization.

    Science.gov (United States)

    Shimizu, A; Ishizaka, H; Awata, S; Shiraishi, A; Hirasawa, S; Tatezawa, T; Kano, M; Shimodaira, K; Taketomi-Takahashi, A; Tsushima, Y; Endo, K

    2009-01-01

    Vaporization around the radiofrequency (RF) electrode after RF application (RFA) limits the RF ablation area. To determine whether saturated saline injected into the area of vaporization after initial RFA extends ablation area after further RFA. RFA was performed in 18 ex vivo porcine livers and four in vivo rabbit erector spinae muscles. An RF electrode was used to ablate an area with 40W of parallel current for 15 min. The ablation margin was determined using a thermocouple, and the radius of the ablated area was measured. After RF electrode removal, saturated saline was infused through a percutaneous ethanol injection needle into the site of the original RFA in 11 liver samples and two erector spinae muscles. Three minutes later, RFA was resumed for 15 min. The remaining seven control liver samples and two spinae muscles received RFA without saline injection. The radius of the final ablated area was then measured. In the ex vivo study, injection of saturated saline significantly decreased tissue impedance (87.7+/-9.4 to 51.1+/-9.7 Omega, P+/-3.0 to 25.0+/-3.6 mm, Pvaporization around the RF electrode, followed by additional RFA, caused concentric expansion of the final ablation area, facilitating more efficient tumor ablation.

  18. Kupa Tedavisi ve Hacamat

    OpenAIRE

    Okumuş, Müyesser

    2016-01-01

    Antik çağlardan bu yana, tamamlayıcı ve geleneksel tedavi, insan sağlığı için önemli bir rol oynamıştır. Tamamlayıcı ve geleneksel tedavi uygulamalarından olan kupa (yaş veya kuru kupa tedavisi) tedavisi konvansiyonel tedaviye cevap vermeyen birçok bozukluklarda terapötik etkiye sahip olduğu iddia edilmektedir. Bu derleme, ilgili literatürün ışığında kupa tedavisi tanımlamasını, tarihçesini, uygulama tekniklerini, mekanizmasını, uygulama bölgelerini ve yan etkilerini özetlemektedir....

  19. Human albumin solution for patients with cirrhosis and acute on chronic liver failure: Beyond simple volume expansion

    Institute of Scientific and Technical Information of China (English)

    Christopher; Valerio; Eleni; Theocharidou; Andrew; Davenport; Banwari; Agarwal

    2016-01-01

    To provide an overview of the properties of human serum albumin(HSA), and to review the evidence for the use of human albumin solution(HAS) in critical illness, sepsis and cirrhosis. A MEDLINE search was performed using the terms "human albumin", "critical illness", "sepsis" and "cirrhosis". The references of retrieved articles were reviewed manually. Studies published between 1980 and 2014 were selected based on quality criteria. Data extraction was performed by all authors. HSA is the main plasma protein contributing greatly to its oncotic pressure. HSA demonstrates important binding properties for endogenous and exogenous toxins, drugs and drug metabolites that account for its anti-oxidant and anti-inflammatory properties. In disease states, hypoalbuminaemia is secondary to decreased HSA production, increased loss or transcapillary leakage into the interstitial space. HSA function can be also altered in disease with reduced albumin binding capacity and increased production of modified isoforms. HAS has been used as volume expander in critical illness, but received criticism due to cost and concerns regarding safety. More recent studies confirmed the safety of HAS, but failed to show any survival benefit compared to the cheaper crystalloid fluids, therefore limiting its use. On the contrary, in cirrhosis there is robust data to support the efficacy of HAS for the prevention of circulatory dysfunction post-large volume paracentesis and in the context of spontaneous bacterial peritonitis, and for the treatment of hepato-renal syndrome and hypervolaemic hyponatraemia. It is likely that not only the oncotic properties of HAS are beneficial in cirrhosis, but also its functional properties, as HAS replaces the dysfunctional HSA. The role of HAS as the resuscitation fluid of choice in critically ill patients with cirrhosis, beyond the established indications for HAS use, should be addressed in future studies.

  20. Stroke volume variation and pleth variability index to predict fluid responsiveness during resection of primary retroperitoneal tumors in Hans Chinese.

    Science.gov (United States)

    Fu, Q; Mi, W D; Zhang, H

    2012-02-01

    Respiration variation in arterial pulse pressure (ΔPP) and pulse oximetry plethysmographic waveform amplitude (ΔPOP) are accurate predictors of fluid responsiveness in mechanically ventilated patients. We hypothesized that stroke volume variation (SVV) and pleth variability index (PVI) can predict fluid responsiveness in mechanically ventilated patients during major surgical procedures in Hans Chinese. This prospective study consisted of fifty-five Hans Chinese patients undergoing resection of primary retroperitoneal tumors (PRPT). During the surgical procedures, hemodynamic data [central venous pressure (CVP), cardiac index (CI), stroke volume index (SVI), SVV, and PVI] were recorded before and after volume expansion (VE) (8 ml•kg-1 of 6% hydroxyethyl starch 130/0.4). Fluid responsiveness was defined as an increase in SVI ≥ 10% after VE. Four patients were excluded from analysis for arrhythmia or obvious hemorrhage during VE. Baseline SVV correlated well with baseline PVI and the changes in SVV was correlated with the changes in PVI (p Chinese.

  1. Subtleties in the calculation of the pressure and pressure tensor of anisotropic particles from volume-perturbation methods and the apparent asymmetry of the compressive and expansive contributions

    Science.gov (United States)

    Brumby, Paul E.; Haslam, Andrew J.; de Miguel, Enrique; Jackson, George

    2011-01-01

    An efficient and versatile method to calculate the components of the pressure tensor for hard-body fluids of generic shape from the perspective of molecular simulation is presented. After due consideration of all the possible repulsive contributions exerted by molecules upon their surroundings during an anisotropic system expansion, it is observed that such a volume change can, for non-spherical molecules, give rise to configurations where overlaps occur. This feature of anisotropic molecules has to be taken into account rigorously as it can lead to discrepancies in the calculation of tensorial contributions to the pressure. Using the condition of detailed balance as a basis, a perturbation method developed for spherical molecules has been extended so that it is applicable to non-spherical and non-convex molecules. From a series of 'ghost' anisotropic volume perturbations the residual contribution to the components of the pressure tensor may be accurately calculated. Comparisons are made with prior methods and, where relevant, results are evaluated against existing data. For inhomogeneous systems this method provides a particularly convenient route to the calculation of the interfacial tension (surface free energy) from molecular simulations.

  2. [Maternal hypotension with low doses of spinal bupivacaine or levobupivacaine and epidural volume expansion with saline for cesarean section].

    Science.gov (United States)

    Guasch, E; Gilsanz, F; Díez, J; Alsina, E

    2010-05-01

    Epidural volume extension (EVE) with saline solution can contribute to greater cephalad spread of drugs injected into the subarachnoid space during cesarean section. We studied the incidence of material hypotension with spinal bupivacaine or levobupivacaine (L-bupivacaine) and the spread after epidural saline injection. After ethics committee approval, we randomized women scheduled for cesarean section to 4 groups to receive 5 mg of 0.25% bupivacaine with (n=51) or without (n=6) saline EVE; 5 mg of 025% L-bupivacaine (n=50); or 6 mg of 03% L-bupivacaine (n=50). All patients also received 25 microg of fentanyl per 2 mL of local hyperbaric spinal anesthetic. In all except the non-EVE group, 10 mL of saline was infused through an epidural catheter 5 minutes after anesthetic infusion. We recorded patient demographic data, procedural and anesthetic times, incision-clamping times, occurrence of hypotension, ephedrine dose required, motor and sensory blockade, requirement for rescue analgesics, and neonatal outcome. After 6 patients had been randomized to the non-EVE group, no further patients were assigned because all the women required rescue analgesics. Demographic data, duration of procedure, time between. incision and delivery, and Apgar scores were similar in all the groups. The incidence of hypotension was lower in the group receiving 5 mg of L-bupivacaine (26% vs. 52.9% in the bupivacaine 5-mg group, and 56% in the 6-mg L-bupivacaine group, P = .04). More women given 5 mg of L-bupivacaine required rescue analgesia (46%) than did those receiving 5 mg of bupivacaine (235%) or 6 mg of L-bupivacaine (28%) (P = .039). Hypotension was associated with a lower umbilical cord pH (P = .001). Ephedrine doses over 20 mg were also associated with a lower umbilical cord pH (P = .031). The incidence of hypotension was lowest in the group anesthetized with 5 mg of L-bupivacaine, but the need for rescue analgesia was greater in this group. Doses of 5 mg and 6 mg may be sufficient

  3. Arterial pressure allows monitoring the changes in cardiac output induced by volume expansion but not by norepinephrine.

    Science.gov (United States)

    Monnet, Xavier; Letierce, Alexia; Hamzaoui, Olfa; Chemla, Denis; Anguel, Nadia; Osman, David; Richard, Christian; Teboul, Jean-Louis

    2011-06-01

    To evaluate to which extent the systemic arterial pulse pressure could be used as a surrogate of cardiac output for assessing the effects of a fluid challenge and of norepinephrine. Observational study. Medical intensive care unit. Patients with an acute circulatory failure who received a fluid challenge (228 patients, group 1) or in whom norepinephrine was introduced or increased (145 patients, group 2). We measured the systolic, diastolic, and mean arterial pressure, pulse pressure, and the transpulmonary thermodilution cardiac output before and after the therapeutic interventions. In group 1, the fluid challenge significantly increased cardiac output by 24% ± 25%. It significantly increased cardiac output by ≥15% (+35% ± 27%) in 142 patients ("responders"). The fluid-induced changes in cardiac output were correlated with the changes in pulse pressure (r = .56, p arterial pressure (r = .55, p arterial pressure (r = .37, p arterial pressure (r = .52, p pressure were significantly related to changes in stroke volume (multiple r = .52) and to age (r = .12). A fluid-induced increase in pulse pressure of ≥17% allowed detecting a fluid-induced increase in cardiac output of ≥15% with a sensitivity of 65[56-72]% and a specificity of 85[76-92]%. The area under the receiver operating characteristic curves for the fluid-induced changes in mean arterial pressure and in diastolic arterial pressure was significantly lower than for pulse pressure. In group 2, the introduction/increase of norepinephrine significantly increased cardiac output by 14% ± 18%. The changes in cardiac output induced by the introduction/increase in the dose of norepinephrine were correlated with the changes in pulse pressure and systolic arterial pressure (r = .21 and .29, respectively, p = .001) but to a significantly lesser extent than in group 1. Pulse pressure and systolic arterial pressure could be used for detecting the fluid-induced changes in cardiac output, in spite of a significant

  4. Synthesis of flexible Fe3O4/C nanofibers with buffering volume expansion performance and their application in lithium-ion batteries

    Science.gov (United States)

    Wu, Qianhui; Zhao, Rongfang; Zhang, Xiue; Li, Wenlong; Xu, Renhua; Diao, Guowang; Chen, Ming

    2017-08-01

    Freestanding binder-free electrodes, as a new generation of electrode material, can effectively improve the energy density of lithium-ion batteries (LIBs). In this paper, novel structured Fe3O4/C composite nanofibers are successful synthesized by a simple electrospinning method followed by a thermal treatment process. The composite nanofibers have the unique internal voids between Fe3O4 nanoparticles and carbon matrix. The Fe3O4/C nanofibers film with good flexibility and excellent electrical conductivity can be directly used to fabricate half-cell without any current collector, binder and additional conductive agent. As anode material for LIBs, the Fe3O4/C composite nanofibers deliver high reversible capacity (762 mA h g-1 at 0.5 A g-1 after 300 cycles). The results show that the internal voids in flexible Fe3O4/C composite nanofibers effectively buffer volume expansion of Fe3O4 in lithium ion intercalation/deintercalation process and avoid the fracture of the nanofibers, which retain the structural integrity and improve the cycling stability of electrode. Therefore, the design and synthesis strategy of flexible nanofibers film are prospective for applications in next-generation flexible LIBs.

  5. Extracellular volume expansion and the preservation of residual renal function in Korean peritoneal dialysis patients: a long-term follow up study.

    Science.gov (United States)

    Rhee, Harin; Baek, Min Ja; Chung, Hyun Chul; Park, Jong Man; Jung, Woo Jin; Park, Soo Min; Lee, Jang Won; Shin, Min Ji; Kim, Il Young; Song, Sang Heon; Lee, Dong Won; Lee, Soo Bong; Kwak, Ihm Soo; Seong, Eun Young

    2016-10-01

    In chronic peritoneal dialysis patients, preservation of residual renal function (RRF) is a major determinant of patient survival, and maintaining sufficient intravascular volume has been hypothesized to be beneficial for the preservation of RRF. The present study aimed to test this hypothesis using multifrequency bioimpedence analyzer (MFBIA), in Korean peritoneal dialysis patients. A total of 129 patients were enrolled in this study. The baseline MFBIA was checked, and the patients were divided into the following two groups: group 1, extracellular water per total body water (ECW/TBW)  median. We followed up the patients, and then we analyzed the changes in the urine output (UO) and the solute clearance (weekly uKt/V) in each group. Data associated with patient and technical survivor were collected by medical chart review. The volume measurement was made using Inbody S20 equipment (Biospace, Seoul, Korea). We excluded the anuric patients at baseline. The median value of ECW/TBW was 0.396. The mean patient age was 49.74 ± 10.01 years, and 62.1 % of the patients were male; most of the patients were on continuous ambulatory peritoneal dialysis (89.1 %). The mean dialysis vintage was 26.20 ± 28.71 months. All of the patients were prescribed hypertensive medication, and 48.5 % of the patients had diabetes. After 25.47 ± 6.86 months of follow up, ΔUO and Δweekly Kt/V were not significantly different in the two groups as follows: ΔUO (-236.07 ± 185.15 in group 1 vs -212.21 ± 381.14 in group 2, p = 0.756); Δ weekly Kt/v (-0.23 ± 0.43 in group 1 vs -0.29 ± 0.49 in group 2, p = 0.461). The patient and technical survivor rate was inferior in the group 2, and in the multivariable analysis, initial hypervolemia was an independent factor that predicts both of the patient mortality [HR 1.001 (1.001-1.086), p = 0.047] and the technical failure [HR 1.024 (1.001-1.048), p = 0.042]. Extracellular volume expansion, measured by MFBIA, does not

  6. Plasma volume expansion for treatment of preeclampsia: a Meta analysis%先兆子痫扩容治疗的Meta分析

    Institute of Scientific and Technical Information of China (English)

    李琳; 田庚; 崔满华

    2012-01-01

    Objective To evaluate effect of plasma volume expansion treatment for preeclampsia by Meta analysis. Methods A comprehensive literature search was performed at PubMed, Medline, Ovid, Embase, CNKI in English language for randomized controlled trials, hand search was also made to retrieve the current reference and research reports. Strict inclusion and exclusion criteria were applied to choose original research, and for quality assessment and data extraction, the software Revman 5. 0 was used for the Meta analysis. Results A total of 5 reports met the inclusion criteria of, including a total of 297 patients. Meta analysis results suggest that the volume - expansion group, compared with non - expansion groups: ① had no statistically significant difference in cesarean section rate, RR = 1.08, 95% CI; 0. 96 ~ 1.22, P = 0.19, ②the difference in the rate of premature delivery was not statistically significant between two groups, RR = 0.91, 95%C7;0.26 ~3.22, P = 0.89. ③perinatal mortality rate had no significant difference between the two groups, RR = 1. 65 , 95% C/;0. 77 ~ 3. 54, P = 0. 20.④the proportion of Apgar score < 7 had no significant difference between the two groups, RR = 1. 11, 95% C/:0. 54 ~ 2. 28 , P = 0. 77. ⑤the ratio of an additional drugs had no significant difference, RR = 1. 91, 95% C/:0. 90 ~ 4. 05, P = 0. 09. Conclusion The volume expansion does not improve the treatment of preeclampsia maternal cesarean section rate, perinatal mortality, Apgar score < 7 and the application of an additional drug ( magnesium sulfate and antihypertensive drugs ) ratio.%目的 通过Meta分析的方法评价先兆子痫扩容治疗的临床疗效.方法 检索1979 ~2010年中外文数据库收录的公开发表与研究目的相关的随机对照试验的文献,手工检索当前能够检索到的参考资料及研究报告.制定严格的纳入与排除标准,选择原始研究并对其进行质量评价和数据提取,利用Revman5.0版软件对所纳

  7. Curvas pressão-volume e expansão foliar em cultivares de algodoeiro submetidos à défcit hídrico Pressure-volume curves and leaf expansion in cotton cultivars under water deficit

    Directory of Open Access Journals (Sweden)

    Celso Jamil Marur

    1999-07-01

    Full Text Available Foi avaliado o comportamento de dois cultivares de algodoeiro em resposta ao déficit hídrico, utilizando-se a expansão foliar como parâmetro discriminatório, bem como a metodologia das curvas pressão-volume para comparar suas habilidades com relação ao ajustamento osmótico. Nos tratamentos estressados, os valores dos Ys em plena turgescência e em turgescência zero obtidos para 'IAC 13-1' foram 0,1 MPa menores do que os obtidos para 'IAC 20'. O ajustamento osmótico em plena turgescência foi de 0.15 e 0.03 MPa, e em turgescência zero foi de 0.18 e 0.07 MPa, respectivamente para os dois cultivares. Os menores valores obtidos para o cultivar 'IAC 13-1' parecem indicar que seus tecidos suportam o estresse por um tempo maior antes das células atingirem o estado de plasmólise. Os valores do módulo volumétrico de elasticidade aumentaram quando os dois cultivares foram submetidos ao estresse hídrico, sendo que o cultivar 'IAC 13-1' parece apresentar paredes celulares com maior elasticidade. Os valores de Ya, antes do amanhecer, em que ocorreu a paralização do crescimento da folha foram -1,04 MPa e -0,98 MPa para os cultivares 'IAC 13-1' e 'IAC 20', respectivamente, mas não detectou-se diferenças significativas entre os dois cultivares.The response of two cotton cultivars to water deficit was studied using leaf expansion and pressure-volume curves method to compare their ability in relation to osmotic adjustment. The osmotic potential at full saturation and at the turgor loss point, for 'IAC 13-1', were 0.1 MPa lower than for `IAC 20' under later stress. Osmotic adjustment at full saturation was 0.15 and 0.03 MPa, and at turgor loss point was 0.18 and 0.07 MPa for 'IAC 13-1'and 'IAC 20', respectively. The low osmotic potential values observed for 'IAC 13-1' suggests that the tissues support water deficit longer, before cells reach plasmolysis. The values for bulk modulus of elasticity were higher when both cultivars were under water

  8. The treatment of spine and chest wall deformities with fused ribs by expansion thoracostomy and insertion of vertical expandable prosthetic titanium rib: growth of thoracic spine and improvement of lung volumes.

    Science.gov (United States)

    Emans, John B; Caubet, Jean François; Ordonez, Claudia L; Lee, Edward Y; Ciarlo, Michelle

    2005-09-01

    Prospective clinical trial of vertical expandable prosthetic titanium rib (VEPTR) in patients with combined spine and chest wall deformity with scoliosis and fused ribs. Report the efficacy and safety of expansion thoracostomy and VEPTR surgery in the treatment of thoracic insufficiency syndrome (TIS) associated with fused ribs. Traditional attitudes toward early-onset combined chest and spine deformity assume that thoracic deformity is best controlled by treatment directed at spine deformity, often involving early spinal arthrodesis. Campbell and others have heightened awareness of the interrelationship between lung, chest, and spine development during growth and characterized TIS as the inability of the thorax to support normal respiration or lung growth. Expansion thoracostomy and VEPTR insertion was developed to directly control both spine and chest wall deformity during growth, while permitting continued vertebral column and chest growth at an early stage. Multidisciplinary evaluation of children with combined spine and chest wall deformity included pediatric pulmonologist, thoracic, and orthopedic surgeon evaluations. One or more opening wedge expansion thoracostomies and placement of VEPTR devices were performed as described by Campbell, with repeated device lengthenings during growth. Parameters measured included Cobb angle, length of thoracic spine, CT-derived lung volumes, and in older children pulmonary function tests. Thirty-one patients with fused ribs and TIS were treated, 4 of whom had undergone prior spinal arthrodesis at other institutions with continued progression of deformity. In 30 patients, the spinal deformity was controlled and growth continued in the thoracic spine during treatment at rates similar to normals. Increased volume of the constricted hemithorax and total lung volumes obtained during expansion thoracostomy were maintained at follow-up. Complications included device migration, infection, and brachial plexus palsy. Expansion

  9. NANO PARÇACIKLAR VE NANO TELLER

    OpenAIRE

    Hakan ATEŞ

    2015-01-01

    Bu makale nano parçacık ve nano tellerin sentezi, yapısı ve geniş bir alanda özelliklerinin yanı sıra nano teknoloji hakkında da bir irdelemeyi sunmaktadır. Çalışma nano teknoloji ve malzemeleri tanımlamakta ve kısa bir tarih, üretim teknikleri ve uygulama alanları hakkında bilgi vermektedir.

  10. Expansive Cements

    Science.gov (United States)

    1970-10-01

    sale: is disributici is unlimited = F’)RIWRD Seior Ignacio Soto, Rrecutive President, Instituto Mexicano del Cementc y Concreto , invited Mr. Bryant... Concreto , a.c., Kwidco, D. F., Mexico. Based on info.mation largely obtained from ACT Committee 223, Expansive ’ement. Concretes, ACI Journal, August 1Q70

  11. Gustav Klimt Ve "Beethoven Friz"

    OpenAIRE

    Fırıncı, Mehmet; Zencirci, Dizan Ercivan

    2006-01-01

    Bu makalede, tarihin hemen hemen her döneminde, paralel gelişim gösteren sanatın üç kolu olan resim, müzik ve mimariyi bir araya getiren "Gustav Klimt" ve sanatçının "Ayrılma (Secession)" döneminde meydana getirdiği başyapıt Beethoven Friz incelenecektir.Avusturyalı sanatçı Klimt, Secession binasının mimari durumunu değerlendirip, Beethoven' in 9.Senfonisi'nden ilham alarak yaptığı Beethoven Friz'i resmetmiştir. Döneminde sanat çevresince pek de anlaşılamamı...

  12. The CEVALE2VE case

    CERN Document Server

    Sanchez Pineda, Arturo; The ATLAS collaboration

    2016-01-01

    A virtual research and learning community can be a powerful tool for educational purposes. It has a wide range of possibilities for multi-institution participation, such as synchronous and asynchronous online engagement, decentralized student discussions and academic networking - as well as being cost effective. In this context, the CEVALE2VE virtual community (Centro de Altos Estudios de Altas Energías) is a Venezuelan initiative to support the new generation of researchers in high energy physics (HEP). Its goal is to contribute to the scientific dissemination of fundamental physics and the regional modernization of university education. The members of CEVALE2VE are a group of Venezuelan researchers, currently involved in projects related to the HEP field, and geographically located in different academic institutions of Europe and North America. The project involves several academic institutions in Venezuela and Colombia in order to reach a wide audience, and exploits current communications technologies, wh...

  13. The CEVALE2VE case

    CERN Document Server

    AUTHOR|(INSPIRE)INSPIRE-00237353; The ATLAS collaboration

    2017-01-01

    A virtual research and learning community can be a powerful tool for educational purposes. It has a wide range of possibilities for multi-institution participation, such as synchronous and asynchronous online engagement, decentralized student discussions and academic networking - as well as being cost effective. In this context, the CEVALE2VE virtual community (Centro de Altos Estudios de Altas Energías) is a Venezuelan initiative to support the new generation of researchers in High Energy Physics (HEP). Its goal is to contribute to the scientific dissemination of fundamental physics and the regional modernization of university education. The members of CEVALE2VE are a group of Venezuelan researchers, currently involved in projects related to the HEP field, and geographically located in different academic institutions of Europe and North America. The project involves several academic institutions in Venezuela and Colombia in order to reach a wide audience, and exploits current communications technologies, w...

  14. Hemodynamic response of modified fluid gelatin compared with lactated ringer's solution for volume expansion in emergency resuscitation of hypovolemic shock patients: preliminary report of a prospective, randomized trial.

    Science.gov (United States)

    Wu, J J; Huang, M S; Tang, G J; Kao, W F; Shih, H C; Su, C H; Lee, C H

    2001-05-01

    The objective of this study was to compare the cardiac and hemodynamic responses to a rapid infusion of 1000 ml of modified fluid gelatin (group A) or 1000 ml of lactated Ringer's solution (group B) in emergency room patients suffering from shock. This prospective, randomized, open, noncrossover study was performed at a medical center university hospital in a surgical resuscitation room in the emergency department. The subjects were 34 patients with either hypovolemic or neurogenic shock who were admitted to the emergency room. A resuscitation protocol according to Advanced Trauma Life Support (ATLS) with an additional central venous line or Swan-Ganz catheters for hemodynamic monitoring was used. Physical parameters and hemodynamic variables were measured at baseline and 15 minutes, 30 minutes, and 1 hour after the infusion of each fluid. In both groups the mean arterial blood pressure (MAP), systolic and diastolic pressure, central venous pressure (CVP), and pulmonary artery occlusion pressure (PAOP) increased significantly. The CVP and PAOP increased significantly more in the modified fluid gelatin resuscitation group. In patients with traumatic or neurogenic shock due to acute volume deficiency, there was significantly better hemodynamic improvement, judged by CVP and PAOP measurements using the modified fluid gelatin for volume replacement than with lactated Ringer's solution during the first hour of resuscitation.

  15. Proposed Expansion of German Air Force Operations at Holloman AFB, New Mexico, Environmental Impact Statement. Volume 2: Public Hearing Transcripts and Responses to Comments

    Science.gov (United States)

    1998-04-01

    1 V : 0 V2 0 b) 02 02 viH 0 S0 2 0- 0 H 0 Id r . 01 3 H 0 02 0 a) 02 4. 0 U(a0 02 4 J 0 Hd 0 1 M .) 10 0d $4 H 4) Fi $4 >. 0 c) $4 0 Un M H H) 01 U 0...RESPONSES TO COMMENTS U U I I I I U I I I I I I Response to Oral and Written Comments Presented at the Public HearingsI The following provides responses...which were submitted in writing. Comments provided at the public hearing, either orally or in writing, are included in Volume II of the FEIS. Written

  16. Effect of volume changes on soil-water characteristics of unsaturated expansive soil%考虑体积变化的非饱和膨胀土土水特征

    Institute of Scientific and Technical Information of China (English)

    周葆春; 孔令伟

    2011-01-01

    为探讨吸力作用下膨胀土体变特征对土水特征的影响规律,开展了一系列完整的脱湿阶段试验,获得了5种不同初始孔隙比的荆门压实膨胀土各级吸力下的重力含水率与体积变化。试验结果表明:不同初始孔隙比下的重力含水率一吸力曲线有交叉与聚拢现象;体积含水率一吸力曲线的交叉现象更为显著;而饱和度一吸力曲线未出现交叉,相同吸力下初始孔隙比大的土样具有更低的饱和度,体现出土水特征与体变特征的耦合效应。基于试验成果,从土的基本体积一质量关系出发,以初始孔隙比与吸力为变量,在一个统一的框架内,构建了吸力作用下的体变方程、分别用重力含水率与饱和度表征的土水特征曲线方程,该方程能够描述任意初始孔隙比条件下膨胀土干缩过程中重力含水率、孔隙比与饱和度随吸力的变化规律。%The effects of deformation on soil-water characteristics of expansive soils were investigated. A series of Soil-Water-Characteristic Curve tests were carried out for the Jingmen compacted expansive soil along the main drying paths. Values of gravimetric water content and volume changes of soil samples at dif- ferent levels of suction were measured for five different initial void ratio samples. The test results show that the gravimetric water content-suction curves intersect and merge, while the volumetric water content-suction curves display intersections more remarkably. However, the degree of saturation-suction curves do not inter- sect, indicating that the soil sample of the larger initial void ratio remains the lower degree of saturation under the same suction. These phenomena reflect coupling effects between the soil-water characteristics and the volume change behavior for expansive soils. Based on the test results, three formulas are presented for predicting the gravimetric water content, void ratio and degree of

  17. Low thermal expansion glass ceramics

    CERN Document Server

    1995-01-01

    This book is one of a series reporting on international research and development activities conducted by the Schott group of companies With the series, Schott aims to provide an overview of its activities for scientists, engineers, and managers from all branches of industry worldwide where glasses and glass ceramics are of interest Each volume begins with a chapter providing a general idea of the current problems, results, and trends relating to the subjects treated This volume describes the fundamental principles, the manufacturing process, and applications of low thermal expansion glass ceramics The composition, structure, and stability of polycrystalline materials having a low thermal expansion are described, and it is shown how low thermal expansion glass ceramics can be manufactured from appropriately chosen glass compositions Examples illustrate the formation of this type of glass ceramic by utilizing normal production processes together with controlled crystallization Thus glass ceramics with thermal c...

  18. Analysis of Effect Increase Volume Expansion Water Dispenser in Hetian Kalage’er Hydropower Station%和田喀拉格尔水电站增效扩容水机分析

    Institute of Scientific and Technical Information of China (English)

    虢强

    2015-01-01

    Effect increase volume expansion rebuilding in Hetian Kalage’er Hydropower Station is the first case of vertical turbine generating unit overall replacement and underwater stage II concrete complete removal in Xinjiang.Original turbine generating unit is demolished and the layout among newly-established unit,unit without rebuilding and plant integrity become a key in the project.In the paper,current status is deeply analyzed,and feasible and practical turbine generating unit volume increase capacity,water turbine and power generator structure mode are finally selected.%和田喀拉格尔水电站增效扩容改造是新疆立式水轮发电机组整体更换、水下二期混凝土全部拆除的第一例。原水轮发电机组拆除、新建机组与未改造机组及厂房整体之间的布置成为工程的关键。本文通过对现状的深入分析,最终选取切实可行的水轮发电机组增容容量及水轮机、发电机结构形式。

  19. Thermal expansion in lead zirconate titanate

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    The volume anomalies with temperature variations in tin-modified lead zirconate titanate ceramics are investigated. Experimental results show that the volume changes are related to the phase transitions induced with temperature. The magnitude and orientation of crystal volume changes are dependent on the particular phase transition. When antiferroelectrics is transformed to ferroelectrics or paraelectrics the volume expands. Oppositely when ferroelectrics is transformed to antiferroelectrics or paraelectrics the volume contracts. In the transition of antiferroelectric orthorhombic structure to tetragonal structure or ferroelectric low-temperature rhombohedral structure to high-tem- perature rhombohedral structure, there are also revealed apparent anomalies in the curves of thermal expansion. Among them, the volume strain caused by the transition between antiferroelectrics and ferroelectrics is the biggest in magnitude, and the linear expansion dL/L0 and the expansion coefficient (dL/L0)/dT can reach 2.810?3 and 7.5 × 10?4 K?1 respectively.

  20. Romatoid Artritte Postural Denge ve Dusme Riski

    Directory of Open Access Journals (Sweden)

    Ahmet Inanir

    2013-02-01

    Full Text Available Amac: Bu calismanin amaci Romatoid Artritin denge ve dusme riski uzerine olan etkilerini degerlendirmektir. Gerec ve yontem: Calismaya toplam 70 olgu dahil edildi; bireylerin 35’i Romatoid artrit (11 erkek, 24 kadin, 35’i ise saglikli gonullulerden (16 erkek, 19 kadin olusmakta idi. Hastalar ve saglikli gonulluler denge ve dusme riski acisindan Biodekx Denge Sistemi (BDS ile degerlendirildi. Bulgular: Romatoid Artritli hastalarin yas ortalamasi 46.47±9.47 yil, kontrol grubunun ise 42.97±9.12 yil idi. Gruplar yas ve vucut kitle indeksi (VKI acisindan degerlendirildiginde istatistiksel olarak anlamli fark saptanmadi (sirasiyla, p=0.129, p=0.207. Gruplar Genel Stabilite Indeksi (GSI ve Antero-Posterior Stabilite Indeksi(APSI acisindan degerlendirildiginde istatistiksel olarak anlamli fark tespit edildi (sirasiyla, p<0.001 ve p=0.004. Benzer sekilde, Medio-Lateral Stabilite Indeksi (MLSI ve Dusme Riski Indeksi (DRI acisindan degerlendirildiginde de istatistiksel olarak anlamli fark saptandi (sirasiyla, p<0.001 ve p<0.001. Sonuc: Bu sonuclara gore, calismamizda Romatoid Artritin denge bozuklugu ve dusme riski ile iliskili oldugu ortaya konulmustur. [Cukurova Med J 2013; 38(1.000: 72-77

  1. Flexible Workflow Software enables the Management of an Increased Volume and Heterogeneity of Sensors, and evolves with the Expansion of Complex Ocean Observatory Infrastructures.

    Science.gov (United States)

    Tomlin, M. C.; Jenkyns, R.

    2015-12-01

    Ocean Networks Canada (ONC) collects data from observatories in the northeast Pacific, Salish Sea, Arctic Ocean, Atlantic Ocean, and land-based sites in British Columbia. Data are streamed, collected autonomously, or transmitted via satellite from a variety of instruments. The Software Engineering group at ONC develops and maintains Oceans 2.0, an in-house software system that acquires and archives data from sensors, and makes data available to scientists, the public, government and non-government agencies. The Oceans 2.0 workflow tool was developed by ONC to manage a large volume of tasks and processes required for instrument installation, recovery and maintenance activities. Since 2013, the workflow tool has supported 70 expeditions and grown to include 30 different workflow processes for the increasing complexity of infrastructures at ONC. The workflow tool strives to keep pace with an increasing heterogeneity of sensors, connections and environments by supporting versioning of existing workflows, and allowing the creation of new processes and tasks. Despite challenges in training and gaining mutual support from multidisciplinary teams, the workflow tool has become invaluable in project management in an innovative setting. It provides a collective place to contribute to ONC's diverse projects and expeditions and encourages more repeatable processes, while promoting interactions between the multidisciplinary teams who manage various aspects of instrument development and the data they produce. The workflow tool inspires documentation of terminologies and procedures, and effectively links to other tools at ONC such as JIRA, Alfresco and Wiki. Motivated by growing sensor schemes, modes of collecting data, archiving, and data distribution at ONC, the workflow tool ensures that infrastructure is managed completely from instrument purchase to data distribution. It integrates all areas of expertise and helps fulfill ONC's mandate to offer quality data to users.

  2. Curvas pressão-volume e expansão foliar em cultivares de algodoeiro submetidos à défcit hídrico Pressure-volume curves and leaf expansion in cotton cultivars under water deficit

    OpenAIRE

    Celso Jamil Marur

    1999-01-01

    Foi avaliado o comportamento de dois cultivares de algodoeiro em resposta ao déficit hídrico, utilizando-se a expansão foliar como parâmetro discriminatório, bem como a metodologia das curvas pressão-volume para comparar suas habilidades com relação ao ajustamento osmótico. Nos tratamentos estressados, os valores dos Ys em plena turgescência e em turgescência zero obtidos para 'IAC 13-1' foram 0,1 MPa menores do que os obtidos para 'IAC 20'. O ajustamento osmótico em plena turgescência foi de...

  3. Thermal Expansion of Polyurethane Foam

    Science.gov (United States)

    Lerch, Bradley A.; Sullivan, Roy M.

    2006-01-01

    Closed cell foams are often used for thermal insulation. In the case of the Space Shuttle, the External Tank uses several thermal protection systems to maintain the temperature of the cryogenic fuels. A few of these systems are polyurethane, closed cell foams. In an attempt to better understand the foam behavior on the tank, we are in the process of developing and improving thermal-mechanical models for the foams. These models will start at the microstructural level and progress to the overall structural behavior of the foams on the tank. One of the key properties for model characterization and verification is thermal expansion. Since the foam is not a material, but a structure, the modeling of the expansion is complex. It is also exacerbated by the anisoptropy of the material. During the spraying and foaming process, the cells become elongated in the rise direction and this imparts different properties in the rise direction than in the transverse directions. Our approach is to treat the foam as a two part structure consisting of the polymeric cell structure and the gas inside the cells. The polymeric skeleton has a thermal expansion of its own which is derived from the basic polymer chemistry. However, a major contributor to the thermal expansion is the volume change associated with the gas inside of the closed cells. As this gas expands it exerts pressure on the cell walls and changes the shape and size of the cells. The amount that this occurs depends on the elastic and viscoplastic properties of the polymer skeleton. The more compliant the polymeric skeleton, the more influence the gas pressure has on the expansion. An additional influence on the expansion process is that the polymeric skeleton begins to breakdown at elevated temperatures and releases additional gas species into the cell interiors, adding to the gas pressure. The fact that this is such a complex process makes thermal expansion ideal for testing the models. This report focuses on the thermal

  4. Exaggerated natriuretic response to isotonic volume expansion in hypertensive renal transplant recipients: evaluation of proximal and distal tubular reabsorption by simultaneous determination of renal plasma clearance of lithium and 51Cr-EDTA.

    Science.gov (United States)

    Nielsen, A H; Knudsen, F; Danielsen, H; Pedersen, E B; Fjeldborg, P; Madsen, M; Brøchner-Mortensen, J; Kornerup, H J

    1987-02-01

    In fourteen hypertensive and fourteen normotensive renal transplant recipients, and in a group of thirteen healthy controls, changes in natriuresis, glomerular filtration rate (GFR), and tubular reabsorption of sodium were determined in relation to intravenous infusion of 2 mmol isotonic sodium chloride per kg body weight. An exaggerated natriuresis was demonstrated in the hypertensive renal transplant recipients. This new finding indicates that the augmented natriuresis following plasma volume expansion, which is a characteristic finding in subjects with arterial hypertension, is not mediated by the renal nerves. Investigation of the tubular reabsorption rates of sodium by simultaneous determination of the renal clearance of 51Cr-EDTA and lithium showed that in the hypertensives the changes in tubular handling of sodium were different from those registered in the normotensive subjects. The increased sodium excretion in the hypertensive renal transplant recipients was caused by an increased output of sodium from the proximal tubules which was not fully compensated for by an increased distal reabsorption. Whether this increased delivery of sodium to the distal segments was caused by changes in GFR or in the proximal tubular reabsorption of sodium could not be clarified in the present study and warrants further investigations.

  5. 关于CO2有机溶剂体系液相体积膨胀的研究%Study of the Liquid Phase Volume Expansion for CO2/Organic Solvent Systems

    Institute of Scientific and Technical Information of China (English)

    李志义; 夏远景; 刘学武; 邓小亮; 胡大鹏

    2005-01-01

    The supercritical antisolvent (SAS) process has been developed in recent years for the formation of nanoand micro-particles. It is necessary to study the liquid phase volume expansion (LPVE) and find the relationships between the operating conditions and the LPVE in order to develop a practical method for determining the operation conditions and selecting an organic solvent for SAS process. The PR equation of state with vdW-1 mixing rule is used to calculate the LPVE for CO2/toluene, CO2/acetone and CO2/ethyl acetate systems, and the results show that the LPVE for each CO2/organic solvent system decreases as the temperature increases. The relationship between the LPVE and the solubility of CO2 in the liquid phase for CO2/organic solvent systems is investigated,and the results show that the LPVE is determined directly by the solubility of CO2 in the liquid phase, xCO2, and can be related to xCO2 independently. No matter what system of CO2/organic solvent is and how different the temperature is, the LPVEs have little difference as long as the solubility of CO2 in the liquid phase, xCO2, keeps constant. The lower temperature is always favorable to the SAS process. The higher the solubility of CO2 in an organic solvent under certain operation condition, the more suitable it is to the SAS process.

  6. VE for Lua game programming

    CERN Document Server

    Mishra, Brij Bhushan

    2013-01-01

    This book follows a tutorial approach with examples and step-by-step instructions to help explain the key concepts of the LÖVE framework as well as everything you need to know about game development using the Lua programming language.LÖVE2d for Lua Game Programming is for anyone who is interested in learning about desktop game development.

  7. Low Thermal Expansion Glass Ceramics

    CERN Document Server

    Bach, Hans

    2005-01-01

    This book appears in the authoritative series reporting the international research and development activities conducted by the Schott group of companies. This series provides an overview of Schott's activities for scientists, engineers, and managers from all branches of industry worldwide in which glasses and glass ceramics are of interest. Each volume begins with a chapter providing a general idea of the current problems, results, and trends relating to the subjects treated. This new extended edition describes the fundamental principles, the manufacturing process, and applications of low thermal expansion glass ceramics. The composition, structure, and stability of polycrystalline materials having a low thermal expansion are described, and it is shown how low thermal expansion glass ceramics can be manufactured from appropriately chosen glass compositions. Examples illustrate the formation of this type of glass ceramic by utilizing normal production processes together with controlled crystallization. Thus g...

  8. Factors influencing electric utility expansion. Volume II

    Energy Technology Data Exchange (ETDEWEB)

    Masud, E. [ed.

    1977-01-01

    This report, Vol. 2, submitted by the General Electric Co., identifies factors that should be considered in planning interconnected systems and discusses how these factors relate to one another. The objective is to identify all the factors and classify them by their use and importance in arriving at a decision. Chapter 2 discusses the utility system and its system behavior characteristics, emphasizing behavior that affects the planning of the bulk-power generation and transmission system. Chapter 3 introduces interconnection planning by discussing the new system characteristics brought to operation and planning. Forty-two factors associated with cost, reliability, constraints, and coordination are related to each other by factor trees. Factor trees display the relationship of one factor such as reliability to more-detailed factors which in turn are further related to individual characteristics of facilities. These factor trees provide a structure to the presentation. A questionnaire including the 42 factors was completed by 52 system planners from utility companies and government authorities. The results of these questionnaires are tabulated and presented with pertinent discussion of each factor. Chapter 4 deals with generation planning, recognizing the existence of interconnections. Chapter 5 addresses transmission planning, questions related to reliability and cost measures and constraints, and factors related to both analytical techniques and planning procedures. The chapter ends with a discussion of combined generation-transmission planning. (MCW)

  9. Shrinkage and Expansive Strain of Concrete with Fly Ash and Expansive Agent

    Institute of Scientific and Technical Information of China (English)

    GAO Peiwei; LU Xiaolin; TANG Mingshu

    2009-01-01

    The effects of fly ash and MgO-type expansive agent on the shrinkage and expan-sive strain of concrete with high magnesia cement were investigated. The results show that high volumes of fly ash may reduce the shrinkage strain of concrete and inhibit the expansive strain of concrete with MgO-type expansive agent, but can not eliminate the shrinkage of concrete. MgO-type expansive agent may produce expansive strain and compensate the shrinkage strain of concrete, re-lieve the cracking risk, but the hydration product of magnesia tends to get together in paste and pro-duce expansive cracking of concrete with high magnesia content according to SEM observation.

  10. Effects of pre-anesthetic volume expansion on hemodynamics in painless artificial abortion during intravenous anesthesia%预扩容对无痛人流术中血流动力学的影响

    Institute of Scientific and Technical Information of China (English)

    祝义军; 刘晨霞; 冉国; 冯丽娟

    2012-01-01

    目的 观察乳酸钠林格液预扩容对丙泊酚静脉麻醉下行无痛人流术中血流动力学的影响.方法 选择择期行无痛人流术者80例,随机分为乳酸钠林格液组(R组)和对照组(C组),每组各40例.麻醉前R组以20mL/(kg·h)的速度输入乳酸钠林格液500mL,A组建立静脉通路但不输液.2组麻醉均用丙泊酚、芬太尼静脉麻醉,且麻醉管理相似.观察2组麻醉后1,3,5,10min各时点患者的收缩压、舒张压、平均动脉压、心率、脉搏氧饱和度的变化,记录发生低血压、恶心呕吐及应用麻黄碱的例数.结果 麻醉后1,3,5min各时点C组的平均动脉压与R组比较明显降低(P均<0.05),麻醉后10min 2组的血流动力学趋于稳定,C组低血压、恶心呕吐发生例数及应用麻黄碱的例数多于R组(P均<0.05).结论 丙泊酚、芬太尼静脉麻醉下行无痛人流术,用乳酸钠林格液预扩容能保持患者术中血流动力学稳定,降低低血压、恶心呕吐等不良反应的发生率.%Objective It is to observe the effects of pre - anesthetic volume expansion in painless artificial abortion during intravenous anesthesia with fentanil combined with propofol. Methods 80 patients of early pregnancy with voluntarily induced abortion were randomly divided into group R and group A( n =40 each ). Before anesthesia, the patients of group R were infused with 500 Ml Lactated Ringer, s solution at a rate of 20 Ml/( kg ? H ), the patients of group C weren' t infused any water although vein channel was established. Each group was anesthetized with fentanil combined with propofol. Anesthesia management was similar in both groups. The changes of SBP, DBP, MAP, HR, Sp( O2 ) in 1, 3, 5, 10 min after the anesthesia were observed in each group, the incidence of hypotension and the side effects such as nausea and vomiting were recorded, and the cases used ephedrine were recorded either. Results The MAP of group C were significantly lower than those in group R

  11. Computation of methodology-independent single-ion solvation properties from molecular simulations. III. Correction terms for the solvation free energies, enthalpies, entropies, heat capacities, volumes, compressibilities, and expansivities of solvated ions.

    Science.gov (United States)

    Reif, Maria M; Hünenberger, Philippe H

    2011-04-14

    The raw single-ion solvation free energies computed from atomistic (explicit-solvent) simulations are extremely sensitive to the boundary conditions (finite or periodic system, system or box size) and treatment of electrostatic interactions (Coulombic, lattice-sum, or cutoff-based) used during these simulations. However, as shown by Kastenholz and Hünenberger [J. Chem. Phys. 124, 224501 (2006)], correction terms can be derived for the effects of: (A) an incorrect solvent polarization around the ion and an incomplete or/and inexact interaction of the ion with the polarized solvent due to the use of an approximate (not strictly Coulombic) electrostatic scheme; (B) the finite-size or artificial periodicity of the simulated system; (C) an improper summation scheme to evaluate the potential at the ion site, and the possible presence of a polarized air-liquid interface or of a constraint of vanishing average electrostatic potential in the simulated system; and (D) an inaccurate dielectric permittivity of the employed solvent model. Comparison with standard experimental data also requires the inclusion of appropriate cavity-formation and standard-state correction terms. In the present study, this correction scheme is extended by: (i) providing simple approximate analytical expressions (empirically-fitted) for the correction terms that were evaluated numerically in the above scheme (continuum-electrostatics calculations); (ii) providing correction terms for derivative thermodynamic single-ion solvation properties (and corresponding partial molar variables in solution), namely, the enthalpy, entropy, isobaric heat capacity, volume, isothermal compressibility, and isobaric expansivity (including appropriate standard-state correction terms). The ability of the correction scheme to produce methodology-independent single-ion solvation free energies based on atomistic simulations is tested in the case of Na(+) hydration, and the nature and magnitude of the correction terms for

  12. Různé věkové kategorie ve vztahu k objemu a intenzitě širokého spektra cyklických pohybů hráčů mužské házené Various age category – related differences in the volume and intensity of the large-scale cyclic movements of male players in team handball

    Directory of Open Access Journals (Sweden)

    Maja Dolenec

    2005-02-01

    ány statisticky významné rozdíly mezi kadety a seniory a také mezi kadety a juniory, zatímco mezi seniory a juniory nebyly spatřeny žádné rozdíly. Se zřetelem k rozdílným věkovým kategoriím u hráčů házené jsme očekávali rozdíly v analyzovaných proměnných, protože sportovci patřící do starších věkových kategorií jsou biologicky více vyzrálí a jsou již delší dobu vystaveni funkčnímu tréninku. Z tohoto důvodu mají možnost vykonávat více cyklických aktivit ve velkém měřítku během zápasu a strávit větší procento času ve vyšší rychlostní třídě. The aim of this study was to identify differences in the volume and intensity of large-scale cyclic movement activities performed by handball players of three age categories – cadet men (aged between 15 and 17 years, junior men (aged between 17 and 20 years and senior men (aged 20 years or over. For this purpose six experimental model matches (2 × 20 min, played by the Slovenian male handball teams, were analyzed. Th

  13. Kapak ve İçindekiler

    Directory of Open Access Journals (Sweden)

    Kapak İçindekiler

    2015-01-01

    Full Text Available Zentralblatt MATH, Chemical Abstract, CAB Abstract ve EBSCO Host indeksleri tarafından taranmaktadır. Indexed in Zentralblatt MATH, Chemical Abstract, CAB Abstract and EBSCO Host indexes

  14. Kapak ve İçindekiler

    Directory of Open Access Journals (Sweden)

    Kapak İçindekiler

    2014-06-01

    Full Text Available Zentralblatt MATH, Chemical Abstract, CAB Abstract ve EBSCO Host indeksleri tarafından taranmaktadır. Indexed in Zentralblatt MATH, Chemical Abstract, CAB Abstract and EBSCO Host indexes

  15. Kapak ve İçindekiler

    Directory of Open Access Journals (Sweden)

    Kapak İçindekiler

    2014-07-01

    Full Text Available Zentralblatt MATH, Chemical Abstract, CAB Abstract ve EBSCO Host indeksleri tarafından taranmaktadır. Indexed in Zentralblatt MATH, Chemical Abstract, CAB Abstract and EBSCO Host indexes

  16. Kapak ve İçindekiler

    Directory of Open Access Journals (Sweden)

    Kapak İçindekiler

    2013-12-01

    Full Text Available Zentralblatt MATH, Chemical Abstract, CAB Abstract ve EBSCO Host indeksleri tarafından taranmaktadır. Indexed in Zentralblatt MATH, Chemical Abstract, CAB Abstract and EBSCO Host indexes

  17. Kapak ve İçindekiler

    Directory of Open Access Journals (Sweden)

    Kapak ve İçindekiler

    2015-09-01

    Full Text Available Zentralblatt MATH, Chemical Abstract, CAB Abstract ve EBSCO Host indeksleri tarafından taranmaktadır. Indexed in Zentralblatt MATH, Chemical Abstract, CAB Abstract and EBSCO Host indexes

  18. Spondilodiskitis tanı ve tedavisi

    OpenAIRE

    Aydinli, Ufuk

    2004-01-01

    Bu çalışmada 4 sponilodiskit olgusu sunuldu ve tartışıldı. Olguların 3'ü erkek, 1'i kadın olup yaşları 17 ile 63 arasında değişmekle idi. Olguların ana şikayeti sırt ve bel ağrısı olup tanı konulana kadar geçen süre 1,5-7 ay arasında idi. İki olguda batın ve loraks operasyonu öyküsü olup, bir olguda ise kronik böbrek yetmezliği vardı. Enfeksiyona neden olan mikroorganizma iki olguda stafilokoküs aureus, bir olguda psödomonas aeroginosa ve bir olguda ise stafilokoküs epidermidis idi....

  19. Kapak ve İçindekiler

    Directory of Open Access Journals (Sweden)

    Kapak İçindekiler

    2014-09-01

    Full Text Available Zentralblatt MATH, Chemical Abstract, CAB Abstract ve EBSCO Host indeksleri tarafından taranmaktadır. Indexed in Zentralblatt MATH, Chemical Abstract, CAB Abstract and EBSCO Host indexes

  20. The Thermal Expansion Of Feldspars

    Science.gov (United States)

    Hovis, G. L.; Medford, A.; Conlon, M.

    2009-12-01

    Hovis and others (1) investigated the thermal expansion of natural and synthetic AlSi3 feldspars and demonstrated that the coefficient of thermal expansion (α) decreases significantly, and linearly, with increasing room-temperature volume (VRT). In all such feldspars, therefore, chemical expansion limits thermal expansion. The scope of this work now has been broadened to include plagioclase and Ba-K feldspar crystalline solutions. X-ray powder diffraction data have been collected between room temperature and 925 °C on six plagioclase specimens ranging in composition from anorthite to oligoclase. When combined with thermal expansion data for albite (2,3,4) a steep linear trend of α as a function of VRT emerges, reflecting how small changes in composition dramatically affect expansion behavior. The thermal expansion data for five synthetic Ba-K feldspars ranging in composition from 20 to 100 mole percent celsian, combined with data for pure K-feldspar (3,4), show α-VRT relationships similar in nature to the plagioclase series, but with a slope and intercept different from the latter. Taken as a group all Al2Si2 feldspars, including anorthite and celsian from the present study along with Sr- (5) and Pb-feldspar (6) from other workers, show very limited thermal expansion that, unlike AlSi3 feldspars, has little dependence on the divalent-ion (or M-) site occupant. This apparently is due to the necessitated alternation of Al and Si in the tetrahedral sites of these minerals (7), which in turn locks the tetrahedral framework and makes the M-site occupant nearly irrelevant to expansion behavior. Indeed, in feldspar series with coupled chemical substitution it is the change away from a 1:1 Al:Si ratio that gives feldspars greater freedom to expand. Overall, the relationships among α, chemical composition, and room-temperature volume provide useful predictive tools for estimating feldspar thermal expansion and give insight into the controls of expansion behavior in

  1. Kokkeuddannelse for døve

    DEFF Research Database (Denmark)

    Hansen, Niels-Henrik Møller; Wittendorff, Nina

    I denne rapport præsenterer vi en evaluering af projektet "Nye veje for unge døve, døvblinde og hørehæmmede i Danmark". Hensigten med dette projekt er at kunne tilbyde døve, døvblinde og hørehæmmede personer et uddannelsestilbud inden for fremstilling af mad. Konkret handler det bl.a. om en kokke...

  2. 40 CFR 35.926 - Value engineering (VE).

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 1 2010-07-01 2010-07-01 false Value engineering (VE). 35.926 Section... engineering (VE). (a) Value engineering proposal. All step 2 grant applications for projects having a... completion of VE analysis and submittal of VE summary reports). (b) Value engineering analysis. For projects...

  3. Cluster expansion in the canonical ensemble

    CERN Document Server

    Pulvirenti, Elena

    2011-01-01

    We consider a system of particles confined in a box $\\La\\subset\\R^d$ interacting via a tempered and stable pair potential. We prove the validity of the cluster expansion for the canonical partition function in the high temperature - low density regime. The convergence is uniform in the volume and in the thermodynamic limit it reproduces Mayer's virial expansion providing an alternative and more direct derivation which avoids the deep combinatorial issues present in the original proof.

  4. Romatoid artritli olan ve olmayan bireylerde periodontal durum, klinik ve laboratuvar parametrelerin değerlendirilmesi

    OpenAIRE

    KARAKUŞ, Özgün

    2010-01-01

    Romatoid Artritli Olan ve Olmayan Bireylerde Periodontal Durum, Klinik ve Laboratuvar Parametrelerin DeğerlendirilmesiSon dönemde yapılan çalışmalar periodontitisin lokal enfeksiyon ve doku yıkımı dışında, çeşitli sistemik sorunların başlama ve ilerleyişinde rol oynadığına dair kanıtlar ortaya koymuştur. Son yıllarda yapılan birçok araştırma ve inceleme periodontal hastalıkla, romatoid artrit arasındaki ilişkiyi ortaya koymuş, veriler romatoid artritli hastaların olmayanl...

  5. On skin expansion.

    Science.gov (United States)

    Pamplona, Djenane C; Velloso, Raquel Q; Radwanski, Henrique N

    2014-01-01

    This article discusses skin expansion without considering cellular growth of the skin. An in vivo analysis was carried out that involved expansion at three different sites on one patient, allowing for the observation of the relaxation process. Those measurements were used to characterize the human skin of the thorax during the surgical process of skin expansion. A comparison between the in vivo results and the numerical finite elements model of the expansion was used to identify the material elastic parameters of the skin of the thorax of that patient. Delfino's constitutive equation was chosen to model the in vivo results. The skin is considered to be an isotropic, homogeneous, hyperelastic, and incompressible membrane. When the skin is extended, such as with expanders, the collagen fibers are also extended and cause stiffening in the skin, which results in increasing resistance to expansion or further stretching. We observed this phenomenon as an increase in the parameters as subsequent expansions continued. The number and shape of the skin expanders used in expansions were also studied, both mathematically and experimentally. The choice of the site where the expansion should be performed is discussed to enlighten problems that can lead to frustrated skin expansions. These results are very encouraging and provide insight into our understanding of the behavior of stretched skin by expansion. To our knowledge, this study has provided results that considerably improve our understanding of the behavior of human skin under expansion.

  6. Using VE to Strategically Plan Our Future

    Energy Technology Data Exchange (ETDEWEB)

    Margie Jeffs; Lori Braase; Alison Conner; Darcie Martinson; Jodi Grgich

    2009-06-01

    The Value Engineering (VE) Methodology is an effective tool for business or project strategic planning. In conjunction with the “Balanced Scorecard Approach” (Drs. Robert Kaplan, PhD, and David Norton, PhD, from the Balanced Scorecard Collaborative/Palladium Group), function analysis can be used to develop strategy maps and scorecards. The FAST diagram provides an integrated approach to strategy map development by formulating a cause and effect relationship and establishing the “how” and “why” behind the strategy map. By utilizing the VE Job Plan, one is able to move from strategic thinking all the way through to execution of the strategy.

  7. Probing the physical determinants of thermal expansion of folded proteins.

    Science.gov (United States)

    Dellarole, Mariano; Kobayashi, Kei; Rouget, Jean-Baptiste; Caro, José Alfredo; Roche, Julien; Islam, Mohammad M; Garcia-Moreno E, Bertrand; Kuroda, Yutaka; Royer, Catherine A

    2013-10-24

    The magnitude and sign of the volume change upon protein unfolding are strongly dependent on temperature. This temperature dependence reflects differences in the thermal expansivity of the folded and unfolded states. The factors that determine protein molar expansivities and the large differences in thermal expansivity for proteins of similar molar volume are not well understood. Model compound studies have suggested that a major contribution is made by differences in the molar volume of water molecules as they transfer from the protein surface to the bulk upon heating. The expansion of internal solvent-excluded voids upon heating is another possible contributing factor. Here, the contribution from hydration density to the molar thermal expansivity of a protein was examined by comparing bovine pancreatic trypsin inhibitor and variants with alanine substitutions at or near the protein-water interface. Variants of two of these proteins with an additional mutation that unfolded them under native conditions were also examined. A modest decrease in thermal expansivity was observed in both the folded and unfolded states for the alanine variants compared with the parent protein, revealing that large changes can be made to the external polarity of a protein without causing large ensuing changes in thermal expansivity. This modest effect is not surprising, given the small molar volume of the alanine residue. Contributions of the expansion of the internal void volume were probed by measuring the thermal expansion for cavity-containing variants of a highly stable form of staphylococcal nuclease. Significantly larger (2-3-fold) molar expansivities were found for these cavity-containing proteins relative to the reference protein. Taken together, these results suggest that a key determinant of the thermal expansivities of folded proteins lies in the expansion of internal solvent-excluded voids.

  8. Role of paraventricular nucleus in natriuresis and diuresis induced by volume expansion in rabbits%兔室旁核对血量扩张引起促钠排泄与利尿的作用

    Institute of Scientific and Technical Information of China (English)

    张波; 林茂樟; 韩桂春

    2000-01-01

    在室旁核(PVN)假损毁兔与PVN损毁兔血量扩张(VE)引起尿流量增加,峰值分别为0.59±0.09与0.31±0.03 ml/min (P0.05),表明PVN损伤可明显减弱 VE 引起的促钠排泄与利尿效应.颈迷走神经切断并不能改变 PVN损伤的上述作用.双侧肾神经切断兔损毁 PVN对VE引起促钠排泄效应无显著影响,但显著减弱其利尿效应 (P<0.02).PVN损毁对VE时肾小球滤过率(GFR)与肾血浆流量(RPF)无显著影响.结果表明PVN参与VE通过迷走传入神经引起促钠排泄与利尿反应的调节,而肾交感传出神经参与其中促钠排泄的作用.

  9. Propeller Research Tunnel - Vought VE-7

    Science.gov (United States)

    1922-01-01

    This picture shows a Vought VE-7 airplane mounted on the test fuselage with an E-2 engine on the plate. The radiator is mounted independently of the engine and is not used for cooling. Cooling water is supplied and returned through rubber hose running back through the fuselage and down the rear post to the floor.

  10. Kapak ve İçindekiler

    Directory of Open Access Journals (Sweden)

    Kapak ve İçindekiler

    2015-12-01

    Full Text Available Süleyman Demirel Üniversitesi Fen Bilimleri Enstitüsü Dergisi, Chemical Abstracts Service , EBSCO Discovery Service, Google Scholar, WorldCat ve Zentralblatt MATH indekslerinde taranmaktadır.Süleyman Demirel University Journal of Natural and Applied Sciences is indexed in Chemical Abstracts Service, EBSCO Discovery Service, Google Scholar, WorldCat and Zentralblatt MATH.

  11. Origami Metamaterials for Tunable Thermal Expansion.

    Science.gov (United States)

    Boatti, Elisa; Vasios, Nikolaos; Bertoldi, Katia

    2017-07-01

    Materials with engineered thermal expansion, capable of achieving targeted area/volume changes in response to variations in temperature, are important for a number of aerospace, optical, energy, and microelectronic applications. While most of the proposed structures with engineered coefficient of thermal expansion consist of bi-material 2D or 3D lattices, here it is shown that origami metamaterials also provide a platform for the design of systems with a wide range of thermal expansion coefficients. Experiments and simulations are combined to demonstrate that by tuning the geometrical parameters of the origami structure and the arrangement of plates and creases, an extremely broad range of thermal expansion coefficients can be obtained. Differently from all previously reported systems, the proposed structure is tunable in situ and nonporous. © 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  12. YAZI TESLİM VE YAYIN KURALLARI

    OpenAIRE

    AKKOR GÜL, Ayşen

    2014-01-01

    KAYNAK GÖSTERİMİ 1.Tüm göndermeler metin içinde sırasıyla yazarın soyadı, tarih ve gerekiyorsa sayfa numaraları ya- zılarak (Soyad, tarih: sayfa aralığı) şeklinde verilmelidir. Aynı kaynaklara yapılan göndermelerde de bu yöntem uygulanmalı ve “a.g.e.”, “ibid.”, “op.cit.” gibi kısaltmalar kullanılmamalıdır. Yayın tarihi olmayan eserler için “tarih yok” anlamında “n.d.” kısaltması kullanılır

  13. YAZI TESLİM VE YAYIN KURALLARI

    OpenAIRE

    AKKOR GÜL, AYŞEN

    2017-01-01

    KAYNAK GÖSTERİMİ 1.Tüm göndermeler metin içinde sırasıyla yazarın soyadı, tarih ve gerekiyorsa sayfa numaraları ya- zılarak (Soyad, tarih: sayfa aralığı) şeklinde verilmelidir. Aynı kaynaklara yapılan göndermelerde de bu yöntem uygulanmalı ve “a.g.e.”, “ibid.”, “op.cit.” gibi kısaltmalar kullanılmamalıdır. Yayın tarihi olmayan eserler için “tarih yok” anlamında “n.d.” kısaltması kullanılır

  14. Kapak ve İçindekiler

    Directory of Open Access Journals (Sweden)

    Kapak İçindekiler

    2016-08-01

    Full Text Available Bu dergi, aşağıda listelenen veri tabanları tarafından taranmaktadır / This journal is indexed by the following abstracting and indexing databasesBASE, CAB Abstracts, CAS (Chemical Abstracts Service, CiteFactor, DOAJ, DRJI, EBSCO Discovery Service (EDS, Google Scholar, JournalTOCs, OAJI, ResearchBib, Ulakbim TR Dizin (Mühendislik ve Temel Bilimler, WorldCat (OCLC, Zentralblatt MATH

  15. Kapak ve İçindekiler

    Directory of Open Access Journals (Sweden)

    Kapak ve İçindekiler

    2016-04-01

    Full Text Available Bu dergi, aşağıda listelenen veri tabanları tarafından taranmaktadır / This journal is indexed by the following abstracting and indexing databasesBASE, CAB Abstracts, CAS (Chemical Abstracts Service, DOAJ, EBSCO Discovery Service (EDS, Google Scholar, JournalTOCs, OAJI, ResearchBib, Ulakbim TR Dizin (Mühendislik ve Temel Bilimler, WorldCat (OCLC, Zentralblatt MATH

  16. Negative thermal expansion

    Energy Technology Data Exchange (ETDEWEB)

    Barrera, G D [Departamento de QuImica, Universidad Nacional de la Patagonia SJB, Ciudad Universitaria, 9000 Comodoro Rivadavia (Argentina); Bruno, J A O [Universidad de Buenos Aires, Facultad de Ciencias Exactas y Naturales, Departamento de QuImica Inorganica, AnalItica y QuImica FIsica, Pabellon 2, Ciudad Universitaria, 1428 Buenos Aires (Argentina); Barron, T H K [School of Chemistry, University of Bristol, Cantock' s Close, Bristol BS8 1TS (United Kingdom); Allan, N L [School of Chemistry, University of Bristol, Cantock' s Close, Bristol BS8 1TS (United Kingdom)

    2005-02-02

    There has been substantial renewed interest in negative thermal expansion following the discovery that cubic ZrW{sub 2}O{sub 8} contracts over a temperature range in excess of 1000 K. Substances of many different kinds show negative thermal expansion, especially at low temperatures. In this article we review the underlying thermodynamics, emphasizing the roles of thermal stress and elasticity. We also discuss vibrational and non-vibrational mechanisms operating on the atomic scale that are responsible for negative expansion, both isotropic and anisotropic, in a wide range of materials. (topical review)

  17. Thermal Expansion "Paradox."

    Science.gov (United States)

    Fakhruddin, Hasan

    1993-01-01

    Describes a paradox in the equation for thermal expansion. If the calculations for heating a rod and subsequently cooling a rod are determined, the new length of the cool rod is shorter than expected. (PR)

  18. Renormalized Volumes with Boundary

    CERN Document Server

    Gover, A Rod

    2016-01-01

    We develop a general regulated volume expansion for the volume of a manifold with boundary whose measure is suitably singular along a separating hypersurface. The expansion is shown to have a regulator independent anomaly term and a renormalized volume term given by the primitive of an associated anomaly operator. These results apply to a wide range of structures. We detail applications in the setting of measures derived from a conformally singular metric. In particular, we show that the anomaly generates invariant (Q-curvature, transgression)-type pairs for hypersurfaces with boundary. For the special case of anomalies coming from the volume enclosed by a minimal hypersurface ending on the boundary of a Poincare--Einstein structure, this result recovers Branson's Q-curvature and corresponding transgression. When the singular metric solves a boundary version of the constant scalar curvature Yamabe problem, the anomaly gives generalized Willmore energy functionals for hypersurfaces with boundary. Our approach ...

  19. Analytical models of volcanic ellipsoidal expansion sources

    Directory of Open Access Journals (Sweden)

    Antonella Amoruso

    2013-11-01

    Full Text Available Modeling non-double-couple earthquakes and surficial deformation in volcanic and geothermal areas usually involves expansion sources. Given an ensemble of ellipsoidal or tensile expansion sources and double-couple ones, it is straightforward to obtain the equivalent single moment tensor under the far-field approximation. On the contrary, the moment tensor interpretation is by no means unique or unambiguous. If the far-field approximation is unsatisfied, the single moment tensor representation is inappropriate. Here we focus on the volume change estimate in the case of single sources, in particular finite pressurized ellipsoidal sources, presenting the expressions for the computation of the volume change and surficial displacement in a closed analytical form. We discuss the implications of different domains of the moment-tensor eigenvalue ratios in terms of volume change computation. We also discuss how the volume change of each source can be obtained from the isotropic component of the total moment tensor, in few cases of coupled sources where the total volume change is null. The new expressions for the computation of the volume change and surficial displacement in case of finite pressurized ellipsoidal sources should make their use easier with respect to the already published formulations.

  20. Colossal negative thermal expansion in reduced layered ruthenate

    Science.gov (United States)

    Takenaka, Koshi; Okamoto, Yoshihiko; Shinoda, Tsubasa; Katayama, Naoyuki; Sakai, Yuki

    2017-01-01

    Large negative thermal expansion (NTE) has been discovered during the last decade in materials of various kinds, particularly materials associated with a magnetic, ferroelectric or charge-transfer phase transition. Such NTE materials have attracted considerable attention for use as thermal-expansion compensators. Here, we report the discovery of giant NTE for reduced layered ruthenate. The total volume change related to NTE reaches 6.7% in dilatometry, a value twice as large as the largest volume change reported to date. We observed a giant negative coefficient of linear thermal expansion α=-115 × 10-6 K-1 over 200 K interval below 345 K. This dilatometric NTE is too large to be attributable to the crystallographic unit-cell volume variation with temperature. The highly anisotropic thermal expansion of the crystal grains might underlie giant bulk NTE via microstructural effects consuming open spaces in the sintered body on heating.

  1. Gyrification from constrained cortical expansion

    CERN Document Server

    Tallinen, Tuomas; Biggins, John S; Mahadevan, L

    2015-01-01

    The exterior of the mammalian brain - the cerebral cortex - has a conserved layered structure whose thickness varies little across species. However, selection pressures over evolutionary time scales have led to cortices that have a large surface area to volume ratio in some organisms, with the result that the brain is strongly convoluted into sulci and gyri. Here we show that the gyrification can arise as a nonlinear consequence of a simple mechanical instability driven by tangential expansion of the gray matter constrained by the white matter. A physical mimic of the process using a layered swelling gel captures the essence of the mechanism, and numerical simulations of the brain treated as a soft solid lead to the formation of cusped sulci and smooth gyri similar to those in the brain. The resulting gyrification patterns are a function of relative cortical expansion and relative thickness (compared with brain size), and are consistent with observations of a wide range of brains, ranging from smooth to highl...

  2. El’ Lisickij grafico costruttivista. La rivista “Vešč’-Gegenstand-Objet”

    Directory of Open Access Journals (Sweden)

    Alice Bravin

    2016-02-01

    Full Text Available This paper analyzes the graphic design of the international art journal “Vešč’-Gegenstand-Objet”, published in Berlin in 1922 by the Russian architect, painter, photographer and designer Lazar’ Markovič Lisickij (1890-1941, better known as El’ Lisickij, together with the Russian writer Il’ja Grigor’evič Èrenburg (1891-1967.Although it lasted only three issues (issues one and two were combined in a single volume which appeared in March/April 1922, while the last number appeared in May 1922, “Vešč’” had a strong influence on contemporary art. It was published in German, French and Russian and was meant both as a bridge between Russia and Europe after the years of war and revolution and as a symbol of the beginning of a new creative era. Mainly focusing on new Suprematist and Constructivist works, the journal included essays on several fields of art such as literature, cinema, theatre, painting, sculpture, architecture and music.In this paper I focus on the innovative graphic design of the two volumes of “Vešč’” entirely realized by El’ Lisickij. Referring to his own theories about book design, Lisickij created a functional and innovative layout and a striking cover, challenging the traditional graphic design practice by using exclusively standard typographic elements such as punctuation marks, typographic lines, geometric forms and typesetting.

  3. Ultrasound attenuation dependence on air compression or expansion processes

    NARCIS (Netherlands)

    Jakevicius, L.; Demcenko, A.; Mardosaite, R.

    2010-01-01

    In this work variation of ultrasonic attenuation coefficient is analyzed in terms of air compression or expansion processes. In closed spaces changing air volume, the ultrasound attenuation coefficient depends on thermodynamic processes which occur during the air volume change. Two limiting cases ar

  4. Composite asymptotic expansions

    CERN Document Server

    Fruchard, Augustin

    2013-01-01

    The purpose of these lecture notes is to develop a theory of asymptotic expansions for functions involving two variables, while at the same time using functions involving one variable and functions of the quotient of these two variables. Such composite asymptotic expansions (CAsEs) are particularly well-suited to describing solutions of singularly perturbed ordinary differential equations near turning points. CAsEs imply inner and outer expansions near turning points. Thus our approach is closely related to the method of matched asymptotic expansions. CAsEs offer two unique advantages, however. First, they provide uniform expansions near a turning point and away from it. Second, a Gevrey version of CAsEs is available and detailed in the lecture notes. Three problems are presented in which CAsEs are useful. The first application concerns canard solutions near a multiple turning point. The second application concerns so-called non-smooth or angular canard solutions. Finally an Ackerberg-O’Malley resonance pro...

  5. Excess Molar Volume of Binary Mixtures of Methylheptenone+Alkanols at 298.15 K

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    Excess molar volume(VE) data on binary liquid mixtures of methylheptenone (MHO) with methanol, ethanol, n-propanol or n-butanol have been determined from the density measurements at 298.15 K and atmospheric pressure. The values of VE in all the systems over the entire composition range are quantified by the Redlich-Kister equation. The effects of the chain length of alkanols on VE are discussed.

  6. Kapak ve İçindekiler

    Directory of Open Access Journals (Sweden)

    Kapak İçindekiler

    2016-12-01

    Full Text Available Bu dergi, aşağıda listelenen veri tabanları tarafından taranmaktadır / This journal is indexed by the following abstracting and indexing databasesBASE, CAB Abstracts, CAS (Chemical Abstracts Service, CiteFactor, CNKI Scholar, DOAJ, DRJI, EBSCO Discovery Service (EDS, Google Scholar, Index Copernicus, InfoBase Index, JournalTOCs, OAJI, ResearchBib, Ulakbim TR Dizin (Mühendislik ve Temel Bilimler, WorldCat (OCLC, Zentralblatt MATH

  7. Kapak ve İçindekiler

    Directory of Open Access Journals (Sweden)

    Kapak ve İçindekiler

    2017-04-01

    Full Text Available Bu dergi, aşağıda listelenen veri tabanları tarafından taranmaktadır / This journal is indexed by the following abstracting and indexing databases:BASE, CAB Abstracts, CAS (Chemical Abstracts Service, CiteFactor, CNKI Scholar, DOAJ, DRJI, EBSCO Discovery Service (EDS, Google Scholar, Index Copernicus, InfoBase Index, JournalTOCs, OAJI, ResearchBib, Ulakbim TR Dizin (Mühendislik ve Temel Bilimler, WorldCat (OCLC, Zentralblatt MATH

  8. Kapak ve İçindekiler

    Directory of Open Access Journals (Sweden)

    Kapak ve İçindekiler

    2017-08-01

    Full Text Available Bu dergi, aşağıda listelenen veri tabanları tarafından taranmaktadır / This journal is indexed by the following abstracting and indexing databases:BASE, CAB Abstracts, CAS (Chemical Abstracts Service, CiteFactor, CNKI Scholar, DOAJ, DRJI, EBSCO Discovery Service (EDS, Google Scholar, Index Copernicus, InfoBase Index, JournalTOCs, OAJI, ResearchBib, Ulakbim TR Dizin (Mühendislik ve Temel Bilimler, WorldCat (OCLC, Zentralblatt MATH

  9. Novel Foraminal Expansion Technique

    Science.gov (United States)

    Senturk, Salim; Ciplak, Mert; Oktenoglu, Tunc; Sasani, Mehdi; Egemen, Emrah; Yaman, Onur; Suzer, Tuncer

    2016-01-01

    The technique we describe was developed for cervical foraminal stenosis for cases in which a keyhole foraminotomy would not be effective. Many cervical stenosis cases are so severe that keyhole foraminotomy is not successful. However, the technique outlined in this study provides adequate enlargement of an entire cervical foraminal diameter. This study reports on a novel foraminal expansion technique. Linear drilling was performed in the middle of the facet joint. A small bone graft was placed between the divided lateral masses after distraction. A lateral mass stabilization was performed with screws and rods following the expansion procedure. A cervical foramen was linearly drilled medially to laterally, then expanded with small bone grafts, and a lateral mass instrumentation was added with surgery. The patient was well after the surgery. The novel foraminal expansion is an effective surgical method for severe foraminal stenosis. PMID:27559460

  10. Tuketici Etnosentrizmi ve Davranis Niyetleri Arasindaki Farkliligin Belirlenmesinde CETSCALE Olcegi

    OpenAIRE

    Murat Akin; Recep Cicek; Esen Gurbuz; M. Emin Inal

    2009-01-01

    Son yillarda cok farkli sebeplerle de olsa giderek ulkemizde de yayginlasmaya baslayan kuresellesme karsitligi sonucu olusan lokal milliyetcilik akimlarinin tuketicilerin satin alma karar surecine olan etkisi yadsinamaz bir gercek olarak karsimizda durmaktadir. Son yillarda ozellikle ABD ve AB karsitligi ile bunlarla boy olcusen Cin karsitligi butun dunyada oldugu gibi ulkemizde de hizla yayginlasmaktadir. Bu ve benzer olgularin tuketim ve satin alma aliskanliklarimiza etkisi basta uluslarara...

  11. Principles of Thermal Expansion in Feldspars

    Science.gov (United States)

    Hovis, Guy; Medford, Aaron; Conlon, Maricate; Tether, Allison; Romanoski, Anthony

    2010-05-01

    Following the recent thermal expansion work of Hovis et al. (1) on AlSi3 feldspars, we have investigated the thermal expansion of plagioclase, Ba-K, and Ca-K feldspar crystalline solutions. X-ray powder diffraction data were collected between room temperature and 925 °C on six natural plagioclase specimens ranging in composition from anorthite to oligoclase, the K-exchanged equivalents of these plagioclase specimens, and five synthetic Ba-K feldspars with compositions ranging from 25 to 99 mol % BaAl2Si2O8. The resulting thermal expansion coefficients (α) for volume have been combined with earlier results for end-member Na- and K-feldspars (2,3). Unlike AlSi3 feldspars, Al2Si2 feldspars, including anorthite and celsian from the present study plus Sr- and Pb-feldspar from other workers (4,5), show essentially constant and very limited thermal expansion, regardless of divalent cation size. In the context of structures where the Lowenstein rule (6) requires Al and Si to alternate among tetrahedra, the proximity of bridging Al-O-Si oxygen ions to divalent neighbors (ranging from 0 to 2) produces short Ca-O (or Ba-O) bonds (7,8) that apparently are the result of local charge-balance requirements (9). Gibbs et al. (10) suggest that short bonds such as these have a partially covalent character. This in turn stiffens the structure. Thus, for feldspar series with coupled substitution the change away from a purely divalent M-site occupant gives the substituting (less strongly bonded) monovalent cations increasingly greater influence on thermal expansion. Overall, then, thermal expansion in the feldspar system is well represented on a plot of α against room-temperature volume, where one sees a quadrilateral bounded by data for (A) AlSi3 feldspars whose expansion behavior is controlled largely by the size of the monovalent alkali-site occupant, (B) Al2Si2 feldspars whose expansion is uniformly limited by partially-covalent bonds between divalent M-site occupants and

  12. Steppe expansion in Patagonia?

    Science.gov (United States)

    Veblen, Thomas T.; Markgraf, Vera

    1988-11-01

    Westward expansion of the Patagonian steppe and retrocession of Andean forests due to increasing aridity over the past one or two millennia has been a persistent theme in the ecological and paleoecological literature for at least half a century. New evidence from pollen profiles, tree-ring analysis, vegetation structure, and photographic and documentary historical sources does not show the expansion of the steppe. Instead, over the past century trees have invaded the steppe as a consequence mainly of human-induced changes in the fire regime, and trees have regenerated in forest areas that were heavily burnt at the onset of European colonization.

  13. Uniform gradient expansions

    Directory of Open Access Journals (Sweden)

    Massimo Giovannini

    2015-06-01

    Full Text Available Cosmological singularities are often discussed by means of a gradient expansion that can also describe, during a quasi-de Sitter phase, the progressive suppression of curvature inhomogeneities. While the inflationary event horizon is being formed the two mentioned regimes coexist and a uniform expansion can be conceived and applied to the evolution of spatial gradients across the protoinflationary boundary. It is argued that conventional arguments addressing the preinflationary initial conditions are necessary but generally not sufficient to guarantee a homogeneous onset of the conventional inflationary stage.

  14. Uniform gradient expansions

    Energy Technology Data Exchange (ETDEWEB)

    Giovannini, Massimo, E-mail: massimo.giovannini@cern.ch [Department of Physics, Theory Division, CERN, 1211 Geneva 23 (Switzerland); INFN, Section of Milan-Bicocca, 20126 Milan (Italy)

    2015-06-30

    Cosmological singularities are often discussed by means of a gradient expansion that can also describe, during a quasi-de Sitter phase, the progressive suppression of curvature inhomogeneities. While the inflationary event horizon is being formed the two mentioned regimes coexist and a uniform expansion can be conceived and applied to the evolution of spatial gradients across the protoinflationary boundary. It is argued that conventional arguments addressing the preinflationary initial conditions are necessary but generally not sufficient to guarantee a homogeneous onset of the conventional inflationary stage.

  15. Kanatlılarda barsak helmintiazisinin patolojisi ve epidemiyolojisi

    OpenAIRE

    Paul, Dipti Rani; Dey, Anita Rani; Bilkis, Farhana; Begum, Nurjahan; Mondal, Md. Motahar Hussain

    2012-01-01

    Amaç: Yerli kanatlılarda barsak helmintlerinin patoloji ve epidemiyolojisini belirlemektir. Gereç ve Yöntem: Lokal marketlerden 109 kanatlının visceral organları toplandı. Helmintlerin identifikasyonu cinsiyet, sezon ve yaşa göre yapıldı. Bulgular: Kanatlıların 79 (%72.47)’unda bir veya daha fazla helmint tespit edildi. İki farklı trematod (Catatropis verrucosa, Echinostoma revolutum), üç farklı sestod (Raillietina tetragona, Raillietina echinobothrida, Raillietina cesticillus) ve iki farklı ...

  16. Dişhekimliği Cerrahisinde Antisepsis ve Asepsis

    OpenAIRE

    2013-01-01

    ÖZETYara enfeksiyonu kısaca anlatıldıktan sonra asepsie ve antisepsisin tarihçesinden ve cerrahideki öneminden bahsedildi.Operasyon sırasında açılan yaraların ve dolayısıyla bütün organizmanın enfekte olmaması için asepsis antisepsisin nasıl gerçekleştirilebileceği ve bilhassa dişhekimlerinin muayenehanelerinde mümkün olan sterilizasyon şekilleri anlatıldı.

  17. Expansion of Pannes

    Science.gov (United States)

    For the Long Island, New Jersey, and southern New England region, one facet of marsh drowning as a result of accelerated sea level rise is the expansion of salt marsh ponds and pannes. Over the past century, marsh ponds and pannes have formed and expanded in areas of poor drainag...

  18. Sieve in expansion

    CERN Document Server

    Kowalski, Emmanuel

    2010-01-01

    This is a survey report for the Bourbaki Seminar (Exp. no. 1028, November 2010) concerning sieve and expanders, in particular the recent works of Bourgain, Gamburd and Sarnak introducing "sieve in orbits", and the related developments concerning expansion properties of Cayley graphs of finite linear groups.

  19. AUTO-EXPANSIVE FLOW

    Science.gov (United States)

    Physics suggests that the interplay of momentum, continuity, and geometry in outward radial flow must produce density and concomitant pressure reductions. In other words, this flow is intrinsically auto-expansive. It has been proposed that this process is the key to understanding...

  20. Sex. Sotidius Strabo Libuscidianus'un Emirnamesi ve Galatia Eyaletinin Augustus ve Tiberius Yönetimindeki Vali listesi

    OpenAIRE

    Coşkun, Altay

    2009-01-01

    Sex. Sotidius Strabo Libuscidianus'un Emirnamesi ve Galatia Eyaletinin Augustus ve Tiberius Yönetimindeki Vali listesi Sagalassos'ta ele geçen ve çift dilli kaleme alınmış bir emirnamede Sex. Sotidius Strabo, Ti. Caesaris Augusti pro pr(aetore) olarak tanımlanmaktadır (AE 1976, nr. 653). Daha önceki yayınlarda Augustus ve Tiberius devirleri arasında Galatia Eyaleti valisi olarak kabul edilmiş olan bu senatörün, sadece Tiberius devrinde valilik yaptığı, buna karşılık T. Helvius Basil...

  1. Thalamic shape abnormalities in antipsychotic naïve schizophrenia

    Directory of Open Access Journals (Sweden)

    Vijay Danivas

    2013-01-01

    Full Text Available Background: Neurodevelopmental hypothesis of schizophrenia states abnormal pruning as one of the pathogenetic mechanism in schizophrenia. Though thalamic volume abnormalities have been documented, the shape differences of thalamus in antipsychotic-free schizophrenia in comparison with age- and sex-matched healthy volunteers need validation. Materials and Methods: We examined antipsychotic naïve schizophrenia patients ( n=60 and age- and sex-matched healthy volunteers ( n=44. The thalamic shape abnormalities were analyzed from their coded structural magnetic resonance imaging (MRI data using three-dimensional automated image analysis software, FMRIB′s (Oxford Center for the functional MRI of the brain tools-FIRST (FMRIB′s Integrated Registration and Segmentation Tool by creating deformable mesh model. Correlation with the psychopathology scores was carried out using F-statistics. Results: Patients with schizophrenia showed significant inward deformations in the regions corresponding to anterior, ventromedial, mediodorsal, and pulvinar nuclei. There was a direct correlation between negative syndrome score and the deformation in the right mediodorsal and right pulvinar nuclei. Conclusion: The inward deformations of thalamus in antipsychotic naive schizophrenia patients correspond to those nuclei which have reciprocal connections with frontal, superior temporal, and anterior cingulate regions and support the neurodevelopmental hypothesis of schizophrenia.

  2. The Hydration Characteristics and Expansion Machanism of Expansive Cement at Low W/B Ratio

    Institute of Scientific and Technical Information of China (English)

    LU Lin-nu; HE Yong-jia; LI Yue; DING Qing-jun; HU Shu-guang

    2003-01-01

    The hydration characteristics and expansion impetus of three kinds of cement paste under freeand confined-curing conditions were investigated, which were respectively mixed with three different kinds of expansive agent at low W/ B ratio. The results show that the hydration products of pure cement paste and paste mixed with expansive agent are same, but the amount of hydration products , un-hydrated C3 S and C2 S are obviously different at the same hydration age. At 3 d age, the amount of CH in pure cement paste is less than that of paste mixed with expaasive agent, but it is reverse when at 28d age. The amount of AFt at 3d and 28d age in pure cement paste is less than those of paste mixed with expansive agent. Regardless of under free- or confined-curing condition, the amount of ettringite produced varies little since 3 d age. The joint effect of the tumefaction of gel-ettringite due to water absorption and the expansive pressure on the pore caased by the crystalloid ettringite is the cause of the volume expansion of cement paste, and the former effect is much greater than the latter .

  3. Naïve Bayes classification in R

    OpenAIRE

    Zhang, Zhongheng

    2016-01-01

    Naïve Bayes classification is a kind of simple probabilistic classification methods based on Bayes’ theorem with the assumption of independence between features. The model is trained on training dataset to make predictions by predict() function. This article introduces two functions naiveBayes() and train() for the performance of Naïve Bayes classification.

  4. Vzorové úlohy ve VHDL

    OpenAIRE

    2009-01-01

    Tato bakalářska prace navazuje na semestralní projekt a zabývá se jazykem VHDL a obvody FPGA a CPLD firmy Xilinx. Dále pak má tato práce za cíl popsat, jak zacházet s vývojovým prostředím WebPack, kde je popsáno jak realizovat nový projekt. Jsou zde popsány různé metody návrhu úlohy v tomto vývojovém prostředí. Nakonec jsou také uvedeny některé vzorové příklady ve VHDL. This bachelor’s study connects on semestral project and is focused on VHDL language and FPGA and CPLD circuits by Xilinx....

  5. Osmanlı Seferlerinde Organizasyon Ve Lojistik The Organization And Logistics Of The Ottoman Flights

    Directory of Open Access Journals (Sweden)

    Uğur KURTARAN

    2012-12-01

    Full Text Available Understanding how the army, one of Ottoman Empire’s main dynamics and whose number reached over hundreds of thousands on occasions, was organized and how its needs were taken care of is not only important in better understanding the founding and the rising of the state but also important in better understanding the reasons for its downfall. Because just like other states founded throughout history, the political history and development of the Ottoman State has beenshaped in connection to its military operations. The success of themilitary operations is dependent on logistics activities, the preparationsand organizations before the military campaign. Indeed, when theOttoman State decided to go in to war, it has made importantpreparations in elevating the administrative and logistical organizationin the country to a more effective level. These preparations beforemilitary campaigns and strategies implemented called today as logisticshave led to the success of the military campaigns carried out in theOttoman State. At this point, the preparations implemented before thecampaigns play a big role in the growth of the state and expansion ofthe boundaries of the empire. So the key element that won or lost thewars for the Ottoman State throughout history was the far better prewarpreparations and organizations they applied much moresuccessfully than their contemporaries. Knowing how and in what waysthese preparations were implemented in the Ottoman State will broadenour perspective and help us better understand the underlying causes inOttoman victories. This study has been prepared in accordance withthese goals and objectives. In this study, it is intended to put forth howthe Ottomans did their preparations before and during the war and togive a different perspective to the current knowledge and experience inthe light of new resources. Osmanlı Devleti’nin temel dinamiklerinden birisi olan ve sayıları bazı dönemlerde yüz binleri geçen ordusunun

  6. Abnormalities of cingulate cortex in antipsychotic-naïve chronic schizophrenia.

    Science.gov (United States)

    Liu, Xiaoyi; Wang, Xijin; Lai, Yunyao; Hao, Chuanxi; Chen, Lei; Zhou, Zhenyu; Yu, Xin; Hong, Nan

    2016-05-01

    While several morphometric studies have postulated a critical contribution of the cingulate cortex (CC) to the pathophysiology of schizophrenia based on abnormalities in CC volume, other studies have been inconclusive. Most such studies have focused only on changes in cortical volume, whereas other morphometric parameters such as surface area and cortical thickness could be more relevant and possibly account for these discrepancies. Furthermore, factors such as antipsychotic drug use and treatment duration may also influence cortical morphology. To clarify the association between schizophrenia and CC deficits, we investigated morphometric abnormalities of the CC in antipsychotic drug (AD)-naïve chronic schizophrenia patients by comparing T1-weighted magnetic resonance images (T1WI-MRI) from patients (n=17) to healthy controls (n=17) using the surface-based morphometry program FreeSurfer. Partial correlations were examined between abnormal morphometric measures and both clinical variables and cognitive performance scores. Compared to healthy controls, drug-naïve schizophrenia patients exhibited significantly lower volumes in both left rostral anterior CC (rACC) and left posterior CC (PCC). These reductions in CC volume resulted from reduced surface area rather than reduced cortical thickness. There was also a significant relationship between left PCC volume and working memory in patients. No significant correlations were observed between CC volume and clinical variables. The results suggest that abnormalities in the CC as manifested by reduced surface area may contribute to cognitive dysfunction in schizophrenia. This article is part of a Special Issue entitled SI: PSC and the brain.

  7. Bigravity from gradient expansion

    Energy Technology Data Exchange (ETDEWEB)

    Yamashita, Yasuho [Yukawa Institute for Theoretical Physics, Kyoto University,606-8502, Kyoto (Japan); Tanaka, Takahiro [Yukawa Institute for Theoretical Physics, Kyoto University,606-8502, Kyoto (Japan); Department of Physics, Kyoto University,606-8502, Kyoto (Japan)

    2016-05-04

    We discuss how the ghost-free bigravity coupled with a single scalar field can be derived from a braneworld setup. We consider DGP two-brane model without radion stabilization. The bulk configuration is solved for given boundary metrics, and it is substituted back into the action to obtain the effective four-dimensional action. In order to obtain the ghost-free bigravity, we consider the gradient expansion in which the brane separation is supposed to be sufficiently small so that two boundary metrics are almost identical. The obtained effective theory is shown to be ghost free as expected, however, the interaction between two gravitons takes the Fierz-Pauli form at the leading order of the gradient expansion, even though we do not use the approximation of linear perturbation. We also find that the radion remains as a scalar field in the four-dimensional effective theory, but its coupling to the metrics is non-trivial.

  8. Operator product expansion algebra

    Energy Technology Data Exchange (ETDEWEB)

    Holland, Jan [CPHT, Ecole Polytechnique, Paris-Palaiseau (France)

    2014-07-01

    The Operator Product Expansion (OPE) is a theoretical tool for studying the short distance behaviour of products of local quantum fields. Over the past 40 years, the OPE has not only found widespread computational application in high-energy physics, but, on a more conceptual level, it also encodes fundamental information on algebraic structures underlying quantum field theories. I review new insights into the status and properties of the OPE within Euclidean perturbation theory, addressing in particular the topics of convergence and ''factorisation'' of the expansion. Further, I present a formula for the ''deformation'' of the OPE algebra caused by a quartic interaction. This formula can be used to set up a novel iterative scheme for the perturbative computation of OPE coefficients, based solely on the zeroth order coefficients (and renormalisation conditions) as initial input.

  9. Local Hubble Expansion: Current State of the Problem

    CERN Document Server

    Dumin, Yurii V

    2016-01-01

    We present a brief qualitative overview of the current state of the problem of Hubble expansion at the sufficiently small scales (e.g., in planetary systems or local intergalactic volume). The crucial drawbacks of the available theoretical treatments are emphasized, and the possible ways to avoid them are outlined. Attention is drawn to a number of observable astronomical phenomena that could be naturally explained by the local Hubble expansion.

  10. El’ Lisickij grafico costruttivista. La rivista “Vešč’-Gegenstand-Objet”

    OpenAIRE

    Alice Bravin

    2016-01-01

    This paper analyzes the graphic design of the international art journal “Vešč’-Gegenstand-Objet”, published in Berlin in 1922 by the Russian architect, painter, photographer and designer Lazar’ Markovič Lisickij (1890-1941), better known as El’ Lisickij, together with the Russian writer Il’ja Grigor’evič Èrenburg (1891-1967).Although it lasted only three issues (issues one and two were combined in a single volume which appeared in March/April 1922, while the last number appeared in May 1922),...

  11. Thermal expansion anomaly regulated by entropy.

    Science.gov (United States)

    Liu, Zi-Kui; Wang, Yi; Shang, ShunLi

    2014-11-13

    Thermal expansion, defined as the temperature dependence of volume under constant pressure, is a common phenomenon in nature and originates from anharmonic lattice dynamics. However, it has been poorly understood how thermal expansion can show anomalies such as colossal positive, zero, or negative thermal expansion (CPTE, ZTE, or NTE), especially in quantitative terms. Here we show that changes in configurational entropy due to metastable micro(scopic)states can lead to quantitative prediction of these anomalies. We integrate the Maxwell relation, statistic mechanics, and first-principles calculations to demonstrate that when the entropy is increased by pressure, NTE occurs such as in Invar alloy (Fe3Pt, for example), silicon, ice, and water, and when the entropy is decreased dramatically by pressure, CPTE is expected such as in anti-Invar cerium, ice and water. Our findings provide a theoretic framework to understand and predict a broad range of anomalies in nature in addition to thermal expansion, which may include gigantic electrocaloric and electromechanical responses, anomalously reduced thermal conductivity, and spin distributions.

  12. GÖRÜNTÜ KURGUSU VE DEVAMLILIK

    Directory of Open Access Journals (Sweden)

    Kağan OLGUNTÜRK

    2011-01-01

    Full Text Available CONTINUITY EDITINGAbstract: As all filmmakers would know, film production is requires three steps. Pre-production, production and post-production (including editing. Although these steps seem detached, they are interrelated. It is impossible for a director to make his plans by avoiding editing which makes editing also a part of pre-production. When we talk about editing, compositional adjustment of two neighbor frames is the main point because it affects directly the viewer. By avoiding jump-cuts the director cannot reach the viewers, which also mean the emotional affect cannot be created. Editing which is called the invisible art, will look more successful if it’s not noticed: Whether it manipulates the viewer or keeps away from that manipulation. Keywords: Editing, Montage, Post-Production, Video. GÖRÜNTÜ KURGUSU VE DEVAMLILIKÖzet: Bilindiği gibi film yapımı, ister film, ister video malzemesi kullanılsın üç aşamadan oluşur. Ön-yapım, yapım, ve son-yapım (bu aşama çekilen filmin kurgulanmasını da içermektedir. Her ne kadar bir film çekimi bu üç farklı aşamadan oluşsa da, bu aşamalar pratikte iç içe geçmiş bir şekildedir. Bir yönetmenin filmini planlarken kurgu aşamasını öngörmemesi oldukça büyük bir eksiklik olacaktır ki, bu durum kurgunun planlanmasını ön-yapım aşamasının parçası haline getirir. Kurgu söz konusu olduğunda arka arkaya gelen iki komşu çerçevenin birbirine uyacak şekilde çekimi, yönetmenin izleyicisi ile buluşup buluşamaması durumunu ortaya çıkarır. Görünmeyen sanat denen, kurgu fark edilmediği oranda başarılı olacaktır. İster izleyiciyi yönlendiren bir eğilime sahip olsun isterse bu yönlendirmeden uzak durmayı amaçlasın.

  13. Operator product expansion algebra

    Energy Technology Data Exchange (ETDEWEB)

    Holland, Jan [School of Mathematics, Cardiff University, Senghennydd Rd, Cardiff CF24 4AG (United Kingdom); Hollands, Stefan [School of Mathematics, Cardiff University, Senghennydd Rd, Cardiff CF24 4AG (United Kingdom); Institut für Theoretische Physik, Universität Leipzig, Brüderstr. 16, Leipzig, D-04103 (Germany)

    2013-07-15

    We establish conceptually important properties of the operator product expansion (OPE) in the context of perturbative, Euclidean φ{sup 4}-quantum field theory. First, we demonstrate, generalizing earlier results and techniques of hep-th/1105.3375, that the 3-point OPE, =Σ{sub C}C{sub A{sub 1A{sub 2A{sub 3}{sup C}}}}, usually interpreted only as an asymptotic short distance expansion, actually converges at finite, and even large, distances. We further show that the factorization identity C{sub A{sub 1A{sub 2A{sub 3}{sup B}}}}=Σ{sub C}C{sub A{sub 1A{sub 2}{sup C}}}C{sub CA{sub 3}{sup B}} is satisfied for suitable configurations of the spacetime arguments. Again, the infinite sum is shown to be convergent. Our proofs rely on explicit bounds on the remainders of these expansions, obtained using refined versions, mostly due to Kopper et al., of the renormalization group flow equation method. These bounds also establish that each OPE coefficient is a real analytic function in the spacetime arguments for non-coinciding points. Our results hold for arbitrary but finite loop orders. They lend support to proposals for a general axiomatic framework of quantum field theory, based on such “consistency conditions” and akin to vertex operator algebras, wherein the OPE is promoted to the defining structure of the theory.

  14. Testing Machine for Expansive Mortar

    CERN Document Server

    Silva, Romulo Augusto Ventura

    2011-01-01

    The correct evaluation of a material property is fundamental to, on their application; they met all expectations that were designed for. In development of an expansive cement for ornamental rocks purpose, was denoted the absence of methodologies and equipments to evaluate the expansive pressure and temperature of expansive cement during their expansive process, having that data collected in a static state of the specimen. In that paper, is described equipment designed for evaluation of pressure and temperature of expansive cements applied to ornamental rocks.

  15. Engineering Properties of Expansive Soil

    Institute of Scientific and Technical Information of China (English)

    DAI Shaobin; SONG Minghai; HUANG Jun

    2005-01-01

    The components of expansive soil were analyzed with EDAX, and it is shown that the main contents of expansive soil in the northern Hubei have some significant effects on engineering properties of expansive soil. Furthermore, the soil modified by lime has an obvious increase of Ca2+ and an improvement of connections between granules so as to reduce the expansibility and contractility of soil. And it also has a better effect on the modified expansive soil than the one modified by pulverized fuel ash.

  16. Patterns of renal dopamine release to regulate diuresis and natriuresis during volume expansion: Role of renal monoamine-oxidase Perfiles de secreción de dopamina renal en la expansión de volumen para regular diuresis y natriuresis: Rol de la monoaminoxidasa renal

    Directory of Open Access Journals (Sweden)

    Verónica de Luca Sarobe

    2010-02-01

    Full Text Available Diuretic and natriuretic effects of renal dopamine (DA are well established. However, in volume expansion the pattern of renal DA release into urine (U DA V and the role of enzymes involved in DA synthesis/degradation have not yet been defined. The objective was to determine the pattern of U DA V during volume expansion and to characterize the involvement of monoamine-oxidase (MAO and aromatic amino-acid decarboxylase (AADC in this response. In this study male Wistar rats were expanded with NaCl 0.9% at a rate of 5% BWt per hour. At the beginning of expansion three groups received a single drug injection as follows: C (vehicle, Control, IMAO (MAO inhibitor Pargyline, 20 mg/kg BWt, i.v. and BNZ (AADC inhibitor Benserazide, 25 mg/kg BWt, i.v.. Results revealed that in C rats U DA V (ng/30 min/100g BWt increased in the first 30 min expansion from 11.5 ± 1.20 to 21.8 ± 3.10 (p La dopamina (DA intrarrenal ejerce efectos diuréticos y natriuréticos. Sin embargo, en los estado de expansión de volumen aún no está bien definido el patrón de liberación de dopamina renal hacia la orina y si cumplen un rol las enzimas involucradas en la síntesis o degradación de la amina. El objetivo del presente trabajo fue determinar el patrón de excreción urinaria de DA (U DA V durante la expansión de volumen, caracterizando la participación de las enzimas monoaminooxidasa (MAO y decarboxilasa de aminoácidos aromáticos (AADC en esta respuesta. Para ello ratas Wistar macho fueron expandidas de volumen con NaCl 0.9% al 5% del peso corporal por hora durante dos horas y divididas en tres grupos, los que al comienzo de la expansión recibieron: C (vehículo, Control, IMAO (Pargilina, inhibidor de MAO, 20 mg/kg PC, i.v. y BNZ (Benserazida, inhibidor de AADC, 25 mg/kg PC, i.v.. Se observó que en C la U DA V (ng/30min/100gPC aumentó durante los primeros 30 minutos de expansión de 11.5 ± 1.20 a 21.8 ± 3.10 (p < 0.05, disminuyendo posteriormente. IMAO mostr

  17. Partners selection of VE based on the organizational field

    Institute of Scientific and Technical Information of China (English)

    GUO Chang-yu; SHOU Jian-min

    2007-01-01

    VE organizational field is a management meaning field formed by the mutual action of resources element. It studies leader and partners in VE as a system, and founds the affiliation among them by the relation of resources. It describes candidate partner enterprise's inner trait and exterior trait by quality parameter and exterior parameter, then analyzes and evaluates them. It combines the qualitative variable and quantitative variable to evaluate the candidate enterprises. It integrates static and dynamic method to help the VE leader to choose partner, which is good for the whole alliance.

  18. Modelling autogenous expansion for magnesia concrete in arch dams

    Institute of Scientific and Technical Information of China (English)

    Feng JIN; Guoxin ZHANG; Xiaoqing LUO; Chuhan ZHANG

    2008-01-01

    Magnesia Concrete is a kind of expansive con-crete used in Chinese hydraulic engineering more and more widely. To evaluate the effects of autogenous expan-sion on the stresses of arch dams, a simple model of auto-genous expansion for Magnesia Concrete in dam engineering is presented. This model is based on three assumptions: 1) the total amount of autogenous expan-sion of Magnesia Concrete is related only to the properties of materials and mixing of concrete; 2) the autogenous expansion of Magnesia Concrete is irreversible due to the irreversibility of hydration reaction of Magnesia in the concrete; 3) the autogenous expansion strain rates of Magnesia Concrete bear a relation between temperature and residual Magnesia per unit volume of concrete. The model is verified by some experimental data of autogen-ous expansion of Magnesia Concrete and field-measured data of an arch dam in China. Embedded into finite ele-ment arch dam simulation software, this model is employed to simulate the effects of autogenous expansion of Magnesia Concrete in hydraulic engineering.

  19. Banque Cantonale de Genève

    CERN Multimedia

    Banque Cantonale de Genève

    2011-01-01

    7e Salon Immobilier BCGE le samedi 3 septembre 2011, de 8 h 30 à 13 h 00, au Centre de formation de Conches À cette occasion, les meilleurs spécialistes professionnels genevois de l’immobilier seront réunis en un seul et même lieu. Si vous le souhaitez, un conseiller spécialisé dans les financements hypothécaires évaluera vos possibilités d’investissement immobilier adaptées à votre situation personnelle. En parallèle, les plus importantes régies immobilières de Genève seront à votre disposition pour vous présenter leurs offres actuelles, ainsi que les projets immobiliers futurs et discuter avec vous de la meilleure stratégie à adopter pour trouver l’objet de vos rêves. De plus, vous aurez la possibilité...

  20. CELESTINA: CALISTO VE MELİBEA’NIN TRAJIKOMEDYASI’NDA ORTAÇAĞ VE RÖNESANS ARASINDA KALMIŞ BİREY VE KADIN

    Directory of Open Access Journals (Sweden)

    Nur Gülümser İLKER

    2017-06-01

    Full Text Available İspanyol Edebiyatının Ortaçağ toplumu ve bireyi arasındaki çatışmayı ele almasıyla en önemli eserlerinden biri olan Celestina: Calisto ve Melibea’nın Trajikomedyası, Rönesans’a dönmüş yüzüyle de önem kazanmaktadır. Yazar Fernando de Rojas’ın ustalıkla ve incelikle yarattığı karakterler vasıtasıyla, dönemin birey algısına odaklanırken, toplumun normlarının bireyler üzerindeki üstünlüğüne tanık oluruz. Aynı zamanda kadına karşı olan bakış açısının da vurgulandığı eserde, evrensel konular gün yüzüne çıkarken, insan, doğasıyla ve içgüdüleriyle işlenerek okuyucuya sunulur. Eserde genç, tutkularının kölesi olmuş Calisto ve saf, geleneklerine bağlı Melibea’nın aşkıyla ve de yaşlı büyücü Celestina’nın tamahkârlığıyla insani duyguların aşırıya kaçması eleştirilir. Topluma uygun olmayan eylemler sonucunda cezalandırılan karakterleriyle eser, didaktik bir metin olma özelliği taşımaktadır. Çalışmanın konusu olarak sözü geçen eserdeki birey ve kadın, Ortaçağ ve Rönesans arasında kalmış olarak ele alınacak ve incelenecektir.

  1. Resonant-state expansion Born Approximation

    CERN Document Server

    Doost, M B

    2015-01-01

    The Born Approximation is a fundamental formula in Physics, it allows the calculation of weak scattering via the Fourier transform of the scattering potential. I extend the Born Approximation by including in the formula the Fourier transform of a truncated basis of the infinite number of appropriately normalised resonant states. This extension of the Born Approximation is named the Resonant-State Expansion Born Approximation or RSE Born Approximation. The resonant-states of the system can be calculated using the recently discovered RSE perturbation theory for electrodynamics and normalised correctly to appear in spectral Green's functions via the flux volume normalisation.

  2. Nisin ve su ürünleri

    Directory of Open Access Journals (Sweden)

    Zafer Ceylan

    2015-06-01

    Full Text Available Nisin doğal ve güvenilir bir gıda katkı maddesidir ve Lactococcus lactis’ ten üretilir. Peynirden balığa ve içeceklere kadar çeşitli gıdalarda katkı maddesi olarak kullanılabilir. Nisin özellikle gram pozitif bakteriler üzerine etkili iken gram negatif ve maya küfler üzerine bir etkisi yoktur. Nisin vücuda alındıktan sonra sindirim enzimleri tarafından inaktif hale getirilir bu nedenle hiçbir toksik etki yaratmaz. Ayrıca, FDA tarafından onaylanan tek bakteriosindir. Nisin sadece toplam bakteriler üzerinde etkin değil aynı zamanda laktik asit bakterileri, koliform ve patojenler üzerine de etkilidir. Nisin su ürünlerinde bulunabilecek L. monocytogenes gibi bazı patojenler üzerine inhibe edici özelliğe sahiptir. Ayrıca; nisin üzerine yapılan pek çok çalışmaya göre, nisin su ürünlerinin mikrobiyolojik güvenliğini sağlar ve raf ömrünü uzatır. Balığın kokusu üzerine olumsuz bir etkisi yoktur. Dahası, balığın doğal kokusunu muhafaza eder. Balıketi pH’sı ve rengi üzerine de olumsuz bir etkisi yoktur. Nisin TVBN, TMA değerleri ve psikrofilik ve mezofilik bakteri sayısının artışını depolama süresince kontrol etmektedir. Ayrıca, nisin vakum paketleme, ışınlama ve diğer katkı maddeleri ile beraber başarı ile kullanılmaktadır. Bu sayede nisin su ürünlerinin raf ömrünü artıran güvenli ve doğal bir katkı maddesi olarak kabul edilmektedir.

  3. Conformal expansions and renormalons

    CERN Document Server

    Gardi, E; Gardi, Einan; Grunberg, Georges

    2001-01-01

    The large-order behaviour of QCD is dominated by renormalons. On the other hand renormalons do not occur in conformal theories, such as the one describing the infrared fixed-point of QCD at small beta_0 (the Banks--Zaks limit). Since the fixed-point has a perturbative realization, all-order perturbative relations exist between the conformal coefficients, which are renormalon-free, and the standard perturbative coefficients, which contain renormalons. Therefore, an explicit cancellation of renormalons should occur in these relations. The absence of renormalons in the conformal limit can thus be seen as a constraint on the structure of the QCD perturbative expansion. We show that the conformal constraint is non-trivial: a generic model for the large-order behaviour violates it. We also analyse a specific example, based on a renormalon-type integral over the two-loop running-coupling, where the required cancellation does occur.

  4. Optical imaging. Expansion microscopy.

    Science.gov (United States)

    Chen, Fei; Tillberg, Paul W; Boyden, Edward S

    2015-01-30

    In optical microscopy, fine structural details are resolved by using refraction to magnify images of a specimen. We discovered that by synthesizing a swellable polymer network within a specimen, it can be physically expanded, resulting in physical magnification. By covalently anchoring specific labels located within the specimen directly to the polymer network, labels spaced closer than the optical diffraction limit can be isotropically separated and optically resolved, a process we call expansion microscopy (ExM). Thus, this process can be used to perform scalable superresolution microscopy with diffraction-limited microscopes. We demonstrate ExM with apparent ~70-nanometer lateral resolution in both cultured cells and brain tissue, performing three-color superresolution imaging of ~10(7) cubic micrometers of the mouse hippocampus with a conventional confocal microscope.

  5. TARHANA ve BESLENME YÖNÜNDEN ÖNEMİ

    OpenAIRE

    COŞKUN, Fatma

    2014-01-01

    Tarhana Türkler tarafından Orta Asya'dan bu yana bilinen ve sevilerek tüketilen geleneksel bir gıdadır. Tarhananın Orta Asya’dan göçen Türkler ve Moğollar tarafından Orta Doğu, Anadolu, Macaristan ve Finlandiya’ya getirildiği ve tanıtıldığı kabul edilmektedir. (Merdol, 1968). Divan-ı Lügati Türk'te tarhana için yazdan kış için saklanan yoğurt anlamında “tar" kelimesi kullanılmıştır (Yücecan ve ark., 1988). Tarhana yapımında buğday ürünleri ve yoğurt karışımına soğan, domates, tuz, kırmızı bib...

  6. Probiyotikler ve Kullanım Alanları

    Directory of Open Access Journals (Sweden)

    Başar Uymaz

    2010-01-01

    Full Text Available Gıdaların üretiminde tüketici sağlığını destekleyici ve immün sistemi uyaran etkilere sahip mikroorganizmaların kullanımı giderek artmaktadır. Bu mikroorganizmaların önemli bir grubunu teşkil eden probiyotiklerin gastrointestinal sistem hastalıklarının engellenmesi ve tedavisinde ve normal mikrofloranın oluşumunda önemli bir rol oynadığı klinik denemelerle belirlenmiştir. Diğer yandan probiyotiklerin, suştan suşa farklılık gösteren gıda koruyucu etkileri ve değişik hastalıkların tedavisinde kullanım potansiyelleri üzerinde çalışmalar devam etmektedir. Özellikle çocuklarda görülen akut diyare ve antibiyotik kullanımına bağlı diyarenin tedavisinde etkin kullanım potansiyeli taşıyan probiyotik preparatları geliştirilmiştir. Bu derleme makalesinde probiyotik suşların seçiminde kullanılan karakteristikler, kullanım olanakları ve tedavi edici potansiyelleri, güncel bilgiler taranarak verilmiştir.

  7. Effects of emergency department expansion on emergency department patient flow.

    Science.gov (United States)

    Mumma, Bryn E; McCue, James Y; Li, Chin-Shang; Holmes, James F

    2014-05-01

    Emergency department (ED) crowding is an increasing problem associated with adverse patient outcomes. ED expansion is one method advocated to reduce ED crowding. The objective of this analysis was to determine the effect of ED expansion on measures of ED crowding. This was a retrospective study using administrative data from two 11-month periods before and after the expansion of an ED from 33 to 53 adult beds in an academic medical center. ED volume, staffing, and hospital admission and occupancy data were obtained either from the electronic health record (EHR) or from administrative records. The primary outcome was the rate of patients who left without being treated (LWBT), and the secondary outcome was total ED boarding time for admitted patients. A multivariable robust linear regression model was used to determine whether ED expansion was associated with the outcome measures. The mean (±SD) daily adult volume was 128 (±14) patients before expansion and 145 (±17) patients after. The percentage of patients who LWBT was unchanged: 9.0% before expansion versus 8.3% after expansion (difference = 0.6%, 95% confidence interval [CI] = -0.16% to 1.4%). Total ED boarding time increased from 160 to 180 hours/day (difference = 20 hours, 95% CI = 8 to 32 hours). After daily ED volume, low-acuity area volume, daily wait time, daily boarding hours, and nurse staffing were adjusted for, the percentage of patients who LWBT was not independently associated with ED expansion (p = 0.053). After ED admissions, ED intensive care unit (ICU) admissions, elective surgical admissions, hospital occupancy rate, ICU occupancy rate, and number of operational ICU beds were adjusted for, the increase in ED boarding hours was independently associated with the ED expansion (p = 0.005). An increase in ED bed capacity was associated with no significant change in the percentage of patients who LWBT, but had an unintended consequence of an increase in ED boarding hours. ED expansion alone does

  8. BUNSEN BEKİ VE SPEKTRAL ANALİZİN DOĞUŞU VE TÜRKİYE’DE TANITILMASI

    OpenAIRE

    Dölen, Emre

    2011-01-01

    Onsekizinci yüzyılın ikinci yarısında Fransa‟da ve İngiltere‟de aydınlatmada kullanmak üzere havagazı üretilmeye başlanmış ve bu gazın borular ile dağıtımı neticesinde, ondokuzuncu yüzyılda Avrupa şehirlerinde gaz lambalarının kullanımı giderek yaygınlaşmıştır. Ondokuzuncu yüzyılın önde gelen kimyagerlerinden Robert Wilhelm Bunsen (1811–1899), sezyum ve rubidyum elementlerini keşfetmiş, spektral analiz kanunlarını ortaya koymuş olmanın yanı sıra, laboratuar araç-gereçleri icad etmede ve geliş...

  9. Enterococcus faecium ve Enterococcus faecalis 'in Starter ve Probiyotik Kültür Özellikleri

    OpenAIRE

    Erginkaya, Zerrin; Yurdakul, Naci Erhan; Karakaş, Ayşegül

    2007-01-01

    ÖzetEnterococcus faecium ve Enterococcus faecalis bazı gıdalarda organoleptik özellikleri iyileştirmenin yanı sıra lipolitik ve esterolitik aktivite, sitrattan yararlanma ile uçucu aromatik bileşikleri sentezleme gibi özellikleri nedeniyle bazı fermente süt ve et ürünlerinin olgunlaştırılması sırasında diğer laktik asit bakterileri ile birlikte starter kültür olarak kullanılmaktadır. Günümüzde Enterococcus 'ların gıda üretiminde starter kültür ve/veya probiyotik olarak kullanılmaları s...

  10. Meyve ve sebze lif konsantreleri ilavesinin hamurun reolojik özellikleri ve bisküvi kalitesine etkileri

    OpenAIRE

    2011-01-01

       Çalışmada; elma, kayısı, portakal, limon, greyfurt, havuç ve balkabağı gibi meyve ve sebzelerden elde edilen lif konsantreleri, iki farklı buğday çeşidinden elde edilen unlara (Gerek-79 ve Guadalupe), değişik oranlarda (% 0, 10, 15, 20 ve 25) katılarak  bunların hamur reolojik özellikleri ile bisküvi kalitesine etkileri araştırılmıştır.

       Araştırmada kullanılan lif konsantrelerinden sebze lif konsantrelerinin...

  11. Burial Ground Expansion Hydrogeologic Characterization

    Energy Technology Data Exchange (ETDEWEB)

    Gaughan , T.F.

    1999-02-26

    Sirrine Environmental Consultants provided technical oversight of the installation of eighteen groundwater monitoring wells and six exploratory borings around the location of the Burial Ground Expansion.

  12. EQUIVALENT MODEL OF EXPANSION OF CEMENT MORTAR UNDER SULPHATE EROSION

    Institute of Scientific and Technical Information of China (English)

    Jue Zhu; Minqiang Jiaug; Jiankang Chen

    2008-01-01

    The expansion property of cement mortar under the attack of sulfate ions is studied by experimental and theoretical methods.First,cement mortars are fabricated with the ratio of water to cement of 0.4,0.6,and 0.8.Secondly,the expansion of specimen immerged in sulphate solution is measured at different times.Thirdly,a theoretical model of expansion of cement mortar under sulphate erosion is suggested by virtue of represent volume element method.In this model, the damage evolution due to the interaction between delayed ettringite and cement mortar is taken into account.Finally,the numerical calculation is performed.The numerical and experimental results indicate that the model perfectly describes the expansion of the cement mortar.

  13. Frequency dependent thermal expansion in binary viscoelasticcomposites

    Energy Technology Data Exchange (ETDEWEB)

    Berryman, James G.

    2007-12-01

    The effective thermal expansion coefficient beta* of abinary viscoelastic composite is shown to be frequency dependent even ifthe thermal expansion coefficients beta A and beta B of both constituentsare themselves frequency independent. Exact calculations for binaryviscoelastic systems show that beta* is related to constituent valuesbeta A, beta B, volume fractions, and bulk moduli KA, KB, as well as tothe overall bulk modulus K* of the composite system. Then, beta* isdetermined for isotropic systems by first bounding (or measuring) K* andtherefore beta*. For anisotropic systems with hexagonal symmetry, theprincipal values of the thermal expansion beta*perp and beta*para can bedetermined exactly when the constituents form a layered system. In allthe examples studied, it is shown explicitly that the eigenvectors of thethermoviscoelastic system possess non-negative dissipation -- despite thecomplicated analytical behavior of the frequency dependent thermalexpansivities themselves. Methods presented have a variety ofapplications from fluid-fluid mixtures to fluid-solid suspensions, andfrom fluid-saturated porous media to viscoelastic solid-solidcomposites.

  14. Orthogonal Query Expansion

    CERN Document Server

    Ackerman, Margareta; Lopez-Ortiz, Alejandro

    2011-01-01

    Over the last fifteen years, web searching has seen tremendous improvements. Starting from a nearly random collection of matching pages in 1995, today, search engines tend to satisfy the user's informational need on well-formulated queries. One of the main remaining challenges is to satisfy the users' needs when they provide a poorly formulated query. When the pages matching the user's original keywords are judged to be unsatisfactory, query expansion techniques are used to alter the result set. These techniques find keywords that are similar to the keywords given by the user, which are then appended to the original query leading to a perturbation of the result set. However, when the original query is sufficiently ill-posed, the user's informational need is best met using entirely different keywords, and a small perturbation of the original result set is bound to fail. We propose a novel approach that is not based on the keywords of the original query. We intentionally seek out orthogonal queries, which are r...

  15. Lattice harmonics expansion revisited

    Science.gov (United States)

    Kontrym-Sznajd, G.; Holas, A.

    2017-04-01

    The main subject of the work is to provide the most effective way of determining the expansion of some quantities into orthogonal polynomials, when these quantities are known only along some limited number of sampling directions. By comparing the commonly used Houston method with the method based on the orthogonality relation, some relationships, which define the applicability and correctness of these methods, are demonstrated. They are verified for various sets of sampling directions applicable for expanding quantities having the full symmetry of the Brillouin zone of cubic and non-cubic lattices. All results clearly show that the Houston method is always better than the orthogonality-relation one. For the cubic symmetry we present a few sets of special directions (SDs) showing how their construction and, next, a proper application depend on the choice of various sets of lattice harmonics. SDs are important mainly for experimentalists who want to reconstruct anisotropic quantities from their measurements, performed at a limited number of sampling directions.

  16. Effectively control negative thermal expansion of single-phase ferroelectrics of PbTiO3-(Bi,La)FeO3 over a giant range.

    Science.gov (United States)

    Chen, Jun; Wang, Fangfang; Huang, Qingzhen; Hu, Lei; Song, Xiping; Deng, Jinxia; Yu, Ranbo; Xing, Xianran

    2013-01-01

    Control of negative thermal expansion is a fundamentally interesting topic in the negative thermal expansion materials in order for the future applications. However, it is a challenge to control the negative thermal expansion in individual pure materials over a large scale. Here, we report an effective way to control the coefficient of thermal expansion from a giant negative to a near zero thermal expansion by means of adjusting the spontaneous volume ferroelectrostriction (SVFS) in the system of PbTiO3-(Bi,La)FeO3 ferroelectrics. The adjustable range of thermal expansion contains most negative thermal expansion materials. The abnormal property of negative or zero thermal expansion previously observed in ferroelectrics is well understood according to the present new concept of spontaneous volume ferroelectrostriction. The present studies could be useful to control of thermal expansion of ferroelectrics, and could be extended to multiferroic materials whose properties of both ferroelectricity and magnetism are coupled with thermal expansion.

  17. Accelerated evolution of the ASPM gene controlling brain size begins prior to human brain expansion

    National Research Council Canada - National Science Library

    Kouprina, Natalay; Pavlicek, Adam; Mochida, Ganeshwaran H; Solomon, Gregory; Gersch, William; Yoon, Young-Ho; Collura, Randall; Ruvolo, Maryellen; Barrett, J Carl; Woods, C Geoffrey; Walsh, Christopher A; Jurka, Jerzy; Larionov, Vladimir

    2004-01-01

    .... The microcephalic brain has a volume comparable to that of early hominids, raising the possibility that some MCPH genes may have been evolutionary targets in the expansion of the cerebral cortex...

  18. Isotropic Negative Thermal Expansion Metamaterials.

    Science.gov (United States)

    Wu, Lingling; Li, Bo; Zhou, Ji

    2016-07-13

    Negative thermal expansion materials are important and desirable in science and engineering applications. However, natural materials with isotropic negative thermal expansion are rare and usually unsatisfied in performance. Here, we propose a novel method to achieve two- and three-dimensional negative thermal expansion metamaterials via antichiral structures. The two-dimensional metamaterial is constructed with unit cells that combine bimaterial strips and antichiral structures, while the three-dimensional metamaterial is fabricated by a multimaterial 3D printing process. Both experimental and simulation results display isotropic negative thermal expansion property of the samples. The effective coefficient of negative thermal expansion of the proposed models is demonstrated to be dependent on the difference between the thermal expansion coefficient of the component materials, as well as on the circular node radius and the ligament length in the antichiral structures. The measured value of the linear negative thermal expansion coefficient of the three-dimensional sample is among the largest achieved in experiments to date. Our findings provide an easy and practical approach to obtaining materials with tunable negative thermal expansion on any scale.

  19. Plasma Volume Expansion in Rats: Effects on Thermoregulation and Exercise,

    Science.gov (United States)

    1988-02-01

    15,18), and especially during the euhydrated and hyperhydrated condition. Methods Adult male Sprague-Dawley rats (Charles River Breeding Laboratories...microcentrifugation. The plasma fraction from the microhematocrit tube was immediately analyzed for protein content by refractometry . The ~ ~ * ~ V...automated spectrophotometer (Stasar IV) and Gilford Diagnostic reagent kits according to methods outlined in the respective technical bulletins. Sodium

  20. On genus expansion of superpolynomials

    CERN Document Server

    Mironov, A; Sleptsov, A; Smirnov, A

    2013-01-01

    Recently it was shown that the (Ooguri-Vafa) generating function of HOMFLY polynomials is the Hurwitz partition function, i.e. that the dependence of the HOMFLY polynomials on representation is naturally captured by symmetric group characters (cut-and-join eigenvalues). The genus expansion and expansion through Vassiliev invariants explicitly demonstrate this phenomenon. In the present letter we claim that the superpolynomials are not functions of such a type: symmetric group characters do not provide an adequate linear basis for their expansions. Deformation to superpolynomials is, however, straightforward in the multiplicative basis:the Casimir operators are beta-deformed to Hamiltonians of the Calogero-Moser-Sutherland system. Applying this trick to the genus and Vassiliev expansions, we observe that the deformation is rather straightforward only for the thin knots. Beyond this family additional algebraically independent terms appear in the Vassiliev and genus expansions. This can suggest that the superpol...

  1. 3,4-Dietilpirolün Sentezi ve Karakterizasyonu

    Directory of Open Access Journals (Sweden)

    B. DEDE

    2009-04-01

    Full Text Available Pirol ve türevleri organik ve biyokimyada önemli heterosiklik bileşiklerdir ve birçok doğal üründe bulunmaktadırlar. Bu çalışmada, porfirin vb. gibi doğal ürünlerin sentezinde kullanılabilecek bir bileşik olan 3,4-dietilpirolün sentezi gerçekleştirilmiştir. Bu amaç için ilk önce bir α-halojenleme reaksiyonu ile bütanalden 2-bromobütanal elde edilmiş ve yine bütanal, morfolin ile etkileştirilerek 1-morfolino-1-büten enamini sentezlenmiştir. 2-Bromobutanal ve 1-morfolino-1-büten uygun şartlarda etkileştirilerek 2,3-dietilsüksinaldehit elde edilmiştir. 2,3-Dietilsüksinaldehitin amonyum karbonat ile reaksiyonu sonucu 3,4-dietilpirol sentezlenmiştir.

  2. Effectively control negative thermal expansion of single-phase ferroelectrics of PbTiO3-(Bi,La)FeO3 over a giant range

    OpenAIRE

    Chen, Jun; Wang, Fangfang; Huang, Qingzhen; Hu, Lei; Song, Xiping; Deng, Jinxia; Yu, Ranbo; Xing, Xianran

    2013-01-01

    Control of negative thermal expansion is a fundamentally interesting topic in the negative thermal expansion materials in order for the future applications. However, it is a challenge to control the negative thermal expansion in individual pure materials over a large scale. Here, we report an effective way to control the coefficient of thermal expansion from a giant negative to a near zero thermal expansion by means of adjusting the spontaneous volume ferroelectrostriction (SVFS) in the syste...

  3. Internal Curing Using Water-releasing Material for High Strength Micro-expansive Concrete

    Institute of Scientific and Technical Information of China (English)

    LU Linnu; YANG Wen; HE Yongjia; WU Jing; HU Shuguang

    2009-01-01

    Due to its low water content,it is difficult for expansive agent to have an effective expansive effect on high strength concrete to compensate its extensive shrinkage and form a certain expansion.To solve this problem,water-releasing material with water storage and releasing characteristics was incorporated into high strength micro-expansive concrete to provide internal curing,and expansive effect of expansive agent was improved.Migration of water from initially saturated water-releasing material to the surrounding hydrating cement paste was investigated.Based on a given efficient diffusion distance of water stored in water-releasing material,the mass and real water-cement ratio of cured cement paste were estimated.At the same time,the effect of internal curing of water-releasing material on the volume deformation of high strength micro-expansive concrete was investigated.

  4. Volume Entropy

    CERN Document Server

    Astuti, Valerio; Rovelli, Carlo

    2016-01-01

    Building on a technical result by Brunnemann and Rideout on the spectrum of the Volume operator in Loop Quantum Gravity, we show that the dimension of the space of the quadrivalent states --with finite-volume individual nodes-- describing a region with total volume smaller than $V$, has \\emph{finite} dimension, bounded by $V \\log V$. This allows us to introduce the notion of "volume entropy": the von Neumann entropy associated to the measurement of volume.

  5. Tissue regeneration during tissue expansion and choosing an expander

    Directory of Open Access Journals (Sweden)

    K Agrawal

    2012-01-01

    Full Text Available This paper reviews the various aspects of tissue regeneration during the process of tissue expansion. "Creep" and mechanical and biological "stretch" are responsible for expansion. During expansion, the epidermis thickens, the dermis thins out, vascularity improves, significant angiogenesis occurs, hair telogen phase becomes shorter and the peripheral nerves, vessels and muscle fibres lengthen. Expansion is associated with molecular changes in the tissue. Almost all these biological changes are reversible after the removal of the expander.This study is also aimed at reviewing the difficulty in deciding the volume and dimension of the expander for a defect. Basic mathematical formulae and the computer programmes for calculating the dimension of tissue expanders, although available in the literature, are not popular. A user-friendly computer programme based on the easily available Microsoft Excel spread sheet has been introduced. When we feed the area of defect and base dimension of the donor area or tissue expander, this programme calculates the volume and height of the expander. The shape of the expander is decided clinically based on the availability of the donor area and the designing of the future tissue movement. Today, tissue expansion is better understood biologically and mechanically. Clinical judgement remains indispensable in choosing the size and shape of the tissue expander.

  6. JOHN LOCKE VE EĞİTİM

    OpenAIRE

    Cihan, Mustafa

    2010-01-01

    John Locke, bir çok konuda olduğu gibi, eğitim konusunda da son derece önemli düşünceler ileri sürmüştür. Locke, kendi felsefi sistemine de bağlı kalarak bilginin zihinden değil, duyum ve deneyimlerden kazanıldığını kabul eder. Buna göre eğitimde, somut, pratik ve empirik olana yönelme esas olandır. Bu bağlamda eğitimin amacı, deneyimin öğrenilmesi ve bu sayede mutluluğun gerçekleştirilmesi olmalıdır. Locke’a göre bunu elde...

  7. Propolis ve Hayvan Beslemede Kullanımı

    OpenAIRE

    Seven, Ismail; AKSU, Taylan; SEVEN, Pınar TATLI

    2014-01-01

    Propolis bal arıları tarafından çeşitli bitki kaynaklarından toplanmış reçinemsi materyalin genel adıdır. Propolisin tam olarak kompozisyonu kaynağına bağlı olarak değişir. Genellikle propolis % 50 reçine ve bitki balsamı, % 30 balmumu, % 10 esansiyel yağlar, % 5 polen ve % 5 diğer çeşitli maddelerden oluşur. Propolis, özellikle etonolik ektraktları, antioksidan, antibakteriyal, antifungal, antiviral ve hepatoprotektif etkileri ile geniş spektrumlu aktivite gösterir, bu yüzden günümüzde diyet...

  8. AHMET MİTHAT EFENDİ VE MADAM GÜLNAR

    OpenAIRE

    İsmail KARACA

    2013-01-01

    Ahmet Mithat Efendi, Madam Gülnar ile 1889 yılında Stockholm'de toplanan VIII. Milletlerarası Müsteşrikler Kongresi'nde tanışır ve dost olurlar. Tanışmalarından itibaren yaklaşık bir ayı birlikte geçiren ve Berlin, Paris gibi Avrupa'nın önemli bazı şehirlerini gezen Ahmet Mithat Efendi ve Madam Gülnar, doğu-batı medeniyeti, ilim-teknik, kadın-aile hayatı, din, felsefe, ahlak, kültür, edebiyat, güzel sanatlar gibi pek çok konuda sohbet ederler, fikir alışverişinde bulunurlar.Ahmet Mithat Efend...

  9. Moloch en expansion

    Directory of Open Access Journals (Sweden)

    Agnès Bouvier

    2009-01-01

    Full Text Available Salammbô, c’est nous. Nous comme héritiers du christianisme mais aussi, nous comme êtres humains, comme appartenant à ce genre humain dont Voltaire disait qu’on ne pouvait en lire l’histoire sans concevoir pour lui de l’horreur. Car c’est l’humanité historique dans son ensemble qui se trouve prise dans l’accusation de molochisme et que Flaubert réunit pêle-mêle dans Carthage, toutes « races » confondues et se « barbarisant » les unes les autres, toutes religions mêlées et se dissolvant au contact les unes des autres. L’humanité est toute entière attachée à Moloch,  ici et ailleurs, hier et aujourd’hui. Le molochisme envahit d’abord la Grèce, c’est-à-dire « nous » au sens où Flaubert l’entendait quand il reprochait à Sainte-Beuve de regretter dans Salammbô « que je n’aie point introduit parmi les Grecs un philosophe, un raisonneur chargé de nous faire un cours de morale, ou commettant de bonnes actions, un monsieur enfin “sentant comme nous” ». Le chemin sanglant de Moloch traverse toute l’Europe et c’est ainsi qu’il touche à une autre partie de nous-mêmes : la Gaule. La présence des Gaulois en arrière-plan de la description de Moloch ne relève pas davantage du remplissage que celle des Grecs dans la procession qui précède le sacrifice des enfants au chapitre XIII. Elle est motivée par le même souci d’envisager « Moloch » dans son épaisseur historique, théologique et anthropologique, dans ce que celui-ci a d’effroyablement totalisant. Les strates de textes qui s’accumulent sous lui construisent d’insondables fondations à la statue remise en service dans le chapitre de Salammbô qui porte son nom. Ce qui était épars est à nouveau rassemblé, ce qui était caché ressort : « Tous les temples à la fois » s’ouvrent pour faire escorte au « Baal suprême », et même ce qu’on ne comprend plus et dont on a perdu le sens resurgit pour l

  10. Mikroarray Teknolojisi ve Bitkilerde Uygulama Alanları

    Directory of Open Access Journals (Sweden)

    M Şahin-Çevik

    2009-04-01

    Full Text Available Son zamanlarda moleküler biyoloji alanındaki gelişmeler organizmaların genomlarının DNA baz dizilerinin belirlenmesi projelerini hızlandırmış ve aralarında model bitki Arabidopsis thaliana ve ekonomik öneme sahip pirinç (Oryza sativa bitkilerinin de bulunduğu birçok organizmanın genomlarının DNA baz dizileri tamamlanmıştır. Veri tabanlarında yer alan ve sürekli artış gösteren bu DNA baz dizisi bilgilerinin fonksiyonel olarak genom düzeyinde analizleri için birtakım metotlara ihtiyaç duyulmaktadır. Mikroarray teknolojisi günümüzde bu amaçla en yaygın olarak kullanılan son derece etkili bir metottur. Bu teknoloji birçok organizmaya ait genom DNA baz dizilerinin tümünü veya bir kısmını içeren genlerin ekspresyon zamanlarını, miktarlarını ve profillerini belirlemek için kullanılmaktadır. Bitkilerde mikroarray teknolojisi abiyotik ve biyotik stresler, meyve olgunlaşması, sirkadian saati, fitokrom A sinyallemesi, tohum gelişmesi ve nitrat asimilasyonunda rol oynayan genlerin ekspresyon analizlerinde kullanılmaktadır.

  11. Thermal expansion and phase transitions of α-AlF{sub 3}

    Energy Technology Data Exchange (ETDEWEB)

    Morelock, Cody R.; Hancock, Justin C. [School of Chemistry and Biochemistry, Georgia Institute of Technology, Atlanta, GA 30332-0400 (United States); Wilkinson, Angus P., E-mail: angus.wilkinson@chemistry.gatech.edu [School of Chemistry and Biochemistry, Georgia Institute of Technology, Atlanta, GA 30332-0400 (United States); School of Materials Science and Engineering, Georgia Institute of Technology, Atlanta, GA 30332-0245 (United States)

    2014-11-15

    ReO{sub 3}-type materials are of interest for their potential low or negative thermal expansion. Many metal trifluorides MF{sub 3} adopt the cubic form of this structure at elevated temperatures, which rhombohedrally distorts upon cooling. The rhombohedral form displays strong positive volume thermal expansion, but cubic MF{sub 3} display much lower and sometimes negative thermal expansion. The expansion behavior of α-AlF{sub 3} was characterized via synchrotron powder diffraction between 323 and 1177 K. α-AlF{sub 3} is rhombohedral at ambient conditions and displays strongly anisotropic thermal expansion. The volume coefficient of thermal expansion (CTE), α{sub V}, at 500 K is ∼86 ppm K{sup −1}, but the linear CTE along the c-axis, α{sub c}, is close to zero. α-AlF{sub 3} becomes cubic on heating to ∼713 K and continues to show positive thermal expansion above the phase transition (α{sub V}(900 K) ∼25 ppm K{sup −1}). - Graphical abstract: α-AlF{sub 3} has a rhombohedrally distorted ReO{sub 3}-type structure at ambient conditions and displays strongly positive volume thermal expansion that is highly anisotropic; the material becomes cubic on heating above ∼713 K and continues to show positive thermal expansion. - Highlights: • ReO{sub 3}-type α-AlF{sub 3} displays strongly anisotropic thermal expansion below 713 K. • α-AlF{sub 3} is cubic above 713 K and maintains positive (isotropic) thermal expansion. • The volume CTE changes from ∼86 to ∼25 ppm K{sup −1} on heating from 500 to 900 K. • The PTE of cubic α-AlF{sub 3} may be due to the presence of local octahedral tilts.

  12. YENY BYR OTOMOBYL KAPI KOLU TASARIM VE YMALATI

    OpenAIRE

    AYKUT, Şeref

    2010-01-01

    Hyzla geli?en teknoloji, artan rekabet ortamy üretimde verimlili?i ve kaliteyi arttyrmayy zorunlu hale getirmekte, bu amaçla yeni yakla?ymlar ortaya konulmaktadyr. Bu çaly?mada farkly bir otomobil kapy kolunun ergonomik tasarymy, üretimi gerçekle?tirilmektedir. CAD yazylymy ile tasarlanan model CAM'e aktarylmakta ve SolidCAM yazylymyyla takym yollary olu?turularak simülasyonla do?rulama yapylmaktadyr. Abaqus ile 600 N de?erine kadar uygulanan yükler altynda gerilme analizi gerçekle?tirilmekte...

  13. Study on Expansion Cracking of Hydration in Concrete Aggregates

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    In accordance with a fresh accident by severe expansion cracks of structural elements,based on systematic detection and analyses such as X-ray diffraction,differential thermal analysis,scanning electron microscory,chemical analysis,petrographic analysis, electronic probe analysis,and atomic absorption spectroscopy analysis, it is pointed out that the dominant reasons lie in the hydration reaction of magnesia in concrete aggregates, resulting in a volume expansion in structure members.A wholly new corresponding strengthening method is applied to the cracked elements and turned out to be effective.

  14. Strong anisotropic thermal expansion in cristobalite-type BPO 4

    Science.gov (United States)

    Achary, S. N.; Tyagi, A. K.

    2004-11-01

    In this communication, the thermal expansion behavior of cristobalite-type BPO 4, determined from high-temperature X-ray diffraction studies, is being reported. BPO 4 crystallizes in tetragonal lattice, with space group I-4 (No. 82) at room temperature, with unit cell parameters: a=4.3447(2), c=6.6415(5) Å and V=125.37(1) Å 3. The tetragonal unit cell parameters at 900 °C are: a=4.3939(2), c=6.6539(6) Å and V=128.46(1) Å 3. The results show a very strong anisotropic expansion in the lattice, with the typical thermal expansion coefficients along a- and c-axis 12.9×10 -6 and 2.1×10 -6/°C, respectively. The volume thermal expansion coefficient of the lattice is 28.2×10 -6/°C in the temperature range of 25-900 °C. The variation of the crystal structure with temperature and the thermal expansion behavior are explained in this manuscript. The role of inter-polyhedral angle on the thermal expansion behavior has also been established.

  15. Balık ve Balık Ürünlerinde Biyojen Aminler ve Önemi

    OpenAIRE

    Özbay Doğu, Sena; Sariçoban, Cemalettin

    2015-01-01

    ÖZET: Biyojen aminler, gıdalarda bulunan serbest amino asitlerin dekarboksilasyonu sonucunda oluşan bileşiklerdir. Histamin, kadaverin, putresin, tiramin, spermin ve spermidin gıdalarda sıklıkla bulunan biyojen aminlerdir. Özellikle balık ve balık ürünleri, biyojen aminlerin oluşumu açısından büyük önem taşımaktadır. Bu gibi ürünlerde biyojen aminler  mikrobiyal dekarboksilaz aktivite ile hızla oluşmaktadır. Yetersiz hijyen, kontaminasyon, hammaddenin mikrobiyal yükü ve sıcaklık gibi faktörle...

  16. Gradient expansion for anisotropic hydrodynamics

    Science.gov (United States)

    Florkowski, Wojciech; Ryblewski, Radoslaw; Spaliński, Michał

    2016-12-01

    We compute the gradient expansion for anisotropic hydrodynamics. The results are compared with the corresponding expansion of the underlying kinetic-theory model with the collision term treated in the relaxation time approximation. We find that a recent formulation of anisotropic hydrodynamics based on an anisotropic matching principle yields the first three terms of the gradient expansion in agreement with those obtained for the kinetic theory. This gives further support for this particular hydrodynamic model as a good approximation of the kinetic-theory approach. We further find that the gradient expansion of anisotropic hydrodynamics is an asymptotic series, and the singularities of the analytic continuation of its Borel transform indicate the presence of nonhydrodynamic modes.

  17. Gradient expansion for anisotropic hydrodynamics

    CERN Document Server

    Florkowski, Wojciech; Spaliński, Michał

    2016-01-01

    We compute the gradient expansion for anisotropic hydrodynamics. The results are compared with the corresponding expansion of the underlying kinetic-theory model with the collision term treated in the relaxation time approximation. We find that a recent formulation of anisotropic hydrodynamics based on an anisotropic matching principle yields the first three terms of the gradient expansion in agreement with those obtained for the kinetic theory. This gives further support for this particular hydrodynamic model as a good approximation of the kinetic-theory approach. We further find that the gradient expansion of anisotropic hydrodynamics is an asymptotic series, and the singularities of the analytic continuation of its Borel transform indicate the presence of non-hydrodynamic modes.

  18. Strategic Complexity and Global Expansion

    DEFF Research Database (Denmark)

    Oladottir, Asta Dis; Hobdari, Bersant; Papanastassiou, Marina

    2012-01-01

    The purpose of this paper is to analyse the determinants of global expansion strategies of newcomer Multinational Corporations (MNCs) by focusing on Iceland, Israel and Ireland. We argue that newcomer MNCs from small open economies pursue complex global expansion strategies (CGES). We distinguish....... The empirical evidence suggests that newcomer MNCs move away from simplistic dualities in the formulation of their strategic choices towards more complex options as a means of maintaining and enhancing their global competitiveness....

  19. Ortopedik Engelli ve Engelli Olmayan Erkek Ergenlerde Benlik Saygısı ve Beden İmajı

    Directory of Open Access Journals (Sweden)

    Sema Kaner

    2000-02-01

    Full Text Available Bu araştırma, ortopedik engelli ve engelli olmayan ergenlerin benlik saygılarını ve beden imajı algılarını karşılaştırmalı olarak incelemeyi amaçlamaktadır. Veriler 55 ortopedik engelli erkek ve 123 normal erkek ergenden Kendine Saygı Ölçeği ve Beden İmajı Anketi ile toplanmıştır. Sonuçlar, grupların benlik saygıları açısından farklı olmadığım, ancak ortopedik engelli erkeklerin beden imajı algılarının engelli olmayan erkeklerinkinden daha olumlu olduğunu göstermektedir. Engelli olmayan erkeklerde benlik saygısı ve beden imajı arasında anlamlı ve olumlu yönde bir ilişki olmasına rağmen, ortopedik engelli erkeklerde bu iki değişken arasında bir ilişki bulunamamıştır. Engelli olmayan erkeklerde benlik saygısını en iyi yordayıcı değişkenler cinsel organlar, boy, ayaklar ve spor yeteneği, ortopedik engellilerde ise bacaklar, ten, omuzlar, beden kılı ve saçlardır. This study was designed to determine whether self-esteem and body image perception differed among orthopedically handicapped and normal adolescents. Data were collected from 55 orthopedically handicapped males and 123 normal males using Self-Esteem Scale and Body image Questionnaire. The results show that there were no significant differences on the self-esteem scores between groups but body image scores ofthe handicapped males in two groups were higher than the normal femalesAlthough it was found that a positive and significant correlation exist between self-esteem and body image perceptions of nonhandicapped males, no such correlation was foundfor handicapped males. The most predictive body aspects of self-esteem were genital organs, height, legs and sports ability in nonhandicapped males, and legs, skin, shoulders, amount of hair on theface and scalp in orthopedically handicapped males.

  20. Isparta ve Yöresinde Üretilen Dolaz (Tort Peynirinin Bazı Kimyasal ve Mikrobiyolojik Özellikleri

    Directory of Open Access Journals (Sweden)

    Bedia ŞİMŞEK

    2009-04-01

    Full Text Available Dolaz (tort peyniri, beyaz peynirlerin peynir altı sularının uzun süre kaynatılması ile yapılan Isparta yöresine ait geleneksel bir peynirdir. Arastırmamızda inek, koyun ve keçi Beyaz peynirlerinin peynir altı sularından yapılan dolaz peynirleri yöreden toplanarak kimyasal ve mikrobiyolojik analizleri gerçeklestirilmistir. Kimyasal olarak kurumadde, yag, titrasyon asitligi (% laktik asit, pH, yag/ kurumadde, toplam azot, suda çözünen azot, protein ve olgunlasma katsayısı saptanmıstır. Yapılan analiz sonuçlarına göre elde edilen ortalama degerler sırasıyla % 52.04±5.70, % 17.70±5.49, % 1.62±0.45, 4.58±0.31, % 34.52±10.78, % 2.38±0.36, % 0.26±0.14, 15.21±2.31 ve 10.95±5.06 olarak belirlenmistir. Mikrobiyolojik analiz sonuçlarına göre toplam aerobik mezofilik bakteri sayısı (TAMB, maya küf sayısı, psikrofilik bakteri sayısı ve Enterobacteriaceae ortalama olarak sırasıyla 5.41±1.14, 4.13±1.26, 3.24±1.19 ve 1.50±0.68 log kob/g olarak saptanmıstır. Koliform ve Staphylococcus aureus sayıları tüm örneklerde <10 1 log kob/g olarak sayılmıstır. KF Streptococcal agar da sayılan enterekoklar ortalama 3.25±1.80 log kob/g, MRS agarda sayılan laktobasiller ortalama sayıları 5.06±0.79 log kob/g, ve M17 agarda sayılan laktokoklar ise ortalama 5.12±0.93 log kob/g olarak bulunmustur.

  1. GloVe C++ v. 1.0

    Energy Technology Data Exchange (ETDEWEB)

    2015-12-02

    This code implements the GloVe algorithm for learning word vectors from a text corpus. It uses a modern C++ approach. This algorithm is described in the open literature in the referenced paper by Pennington, Jeffrey, Richard Socher, and Christopher D. Manning.

  2. Scientific ethics and plagiarism Bilimsel etik ve intihal

    Directory of Open Access Journals (Sweden)

    Nazan Özenç Uçak

    2008-06-01

    Full Text Available This article studies scholarly communication, ethics and unethical behaviors, especially plagiarism. It defines genres of unethical behaviors, their reasons, influence of internet and ways of prevention. It introduces software programs for prevention of plagiarism. Finally the importance of education and the role of librarians are underlined. Bu makalede bilimsel iletişim ve etik konuları ele alınmakta ve bilimsel alanda görülen etik dışı davranışlar incelenmektedir. Özellikle intihal konusu üzerinde durularak, intihalin ne olduğu, türleri, yapılış nedenleri, internetin intihal üzerine etkisi ve önlenmesi konusunda yapılabilecekler irdelenmektedir. İntihalin önlenmesinde kullanılan yazılımlar tanıtılmaktadır. Sonuç olarak eğitimin önemi ve kütüphanecinin rolü üzerinde durulmaktadır.

  3. Le CERN, chance ou risque pour Genève

    CERN Document Server

    Maiani, Luciano; Wenninger, Horst; CERN. Geneva

    1998-01-01

    Le CERN, Chance ou Risque pour Gen?ve? D?bat public contradictoire organis? avec le soutien de la Tribune de Gen?ve Lieu: Salle II, CICG,15 Rue de Varemb?. Date: Lundi 19 octobre 1998, 20h00 D?roulement de la soir?e: 1. Ouverture M. Ren? KÏchlin, Pr?sident du Grand Conseil M. Luciano Maiani, Directeur g?n?ral d?sign? du CERN 2. Introduction: Un regard critique sur le CERN (? d?signer) Le projet LHC (Manfred Buhler Broglin CERN) 3. D?bat th?matique men? par le mod?rateur (Marco Cattaneo, r?dacteur en chef de la Tribune de Gen?ve) entre trois representants de lÕopinion publique (Ren? Longet, d?put? socialiste; Yves de Pr?ville, physicien; Jacques Mirenowicz, chercheur) et trois repr?sentants du Cern (Horst Wenninger, Directeur de la Recherche/Technique, CERN; Manfred Buhler Broglin, Administra-teur du projet LHC, CERN; Maurice Bourquin, Professeur de Physique ? l'Universit? de Gen?ve et D?l?gu? de la Suisse au Conseil du CERN). Les th?mes abord?s seront: Ð A quoi sert le CERN? Ð Quel est lÕimpact ?conomiqu...

  4. Legendre Expansions for Two-Hadron Reactions

    Science.gov (United States)

    Strakovsky, Igor; Azimov, Yakov; Briscoe, William

    2017-01-01

    Modern experimental facilities and detectors provide tremendous volumes of detailed data. For two-hadron reactions, they are usually presented as a set of multiple panels, e . g . , angular distributions at many particular energies. Such presentations lose visuality, and their physical content may be extracted only through some model-dependent treatment. Instead, we suggest to use expansion into the Legendre series with a relatively small number of essential coefficients. This approach was applied in several experimental investigations and demonstrated its higher visualization. This talk presents some general properties of the Legendre coefficients which allow one to extract physical information even without any model-dependent assumptions. The U.S. Department of Energy, Office of Science, Office of Nuclear Physics, Award Numbers DE-SC0014133 and DE-SC0016582 and the Russian Science Foundation, Award No.14-22-00281.

  5. The Determination Study for VE in Raspberry Fruit by HPLC%HPLC 法测定覆盆子中 VE 含量的研究

    Institute of Scientific and Technical Information of China (English)

    孙金旭

    2012-01-01

      This paper analyzes the problems in determination study of VE content in raspberry fruit by HPLC. The study indicates that the suitable determination wavelength is 295 nm and the maximum standard deviation by using this way to determinate the content of VE is 5.53 %. VE content displays an excellent linear relationship with the peak area; the standard curve equation is Y = 6 587.35 x, with a correlation coefficient of 0.999 2. The spike recovery for VE is 96.55 % to 98.43 %. The method is feasible and accurate for determining VE content in raspberry fruit. The content of VE in raspberry fruit is 0.093 5 mg/g.%  建立了 HPLC 测定覆盆子浆果中 VE 含量方法,确定测定波长为295 nm,最大标准偏差5.53%,峰面积与 VE 标准品线性关系良好,标准方程 Y =6587.35 x,相关系数0.9992,加标回收率在96.55%~98.43%之间,此方法用于测定覆盆子浆果 VE 含量准确、可行,经测定覆盆子浆果中 VE 含量为0.0935 mg/g.

  6. Chemical and Thermal Expansion of Calcium-Doped Lanthanum Chromite

    Science.gov (United States)

    Williford, R. E.; Armstrong, T. R.; Gale, J. D.

    2000-02-01

    Atomistic free-energy minimization techniques were used to simulate three simultaneous volumetric shrinkage/expansion phenomena in calcium-doped lanthanum chromite solid oxide fuel cell (SOFC) interconnect materials. Four sets of interatomic potentials were developed and tested over the temperature range 0-1273 K. The predicted unit-cell volumes, elastic properties, volumetric shrinkage due to A-site doping of the ABO3 perovskite (La1-xCax)CrO3, defect-induced volumetric expansion due to reducing atmospheres, and thermal expansion were in reasonable agreement with experiment, though not all concurrently with a single set of potentials. Potentials based either on simple oxides or on partial charge models appeared to give the best overall predictions. Additional experimental data are needed to improve the potentials.

  7. Postoperative volume balance

    DEFF Research Database (Denmark)

    Frost, H; Mortensen, C.R.; Secher, Niels H.

    2017-01-01

    In healthy humans, stroke volume (SV) and cardiac output (CO) do not increase with expansion of the central blood volume by head-down tilt or administration of fluid. Here, we exposed 85 patients to Trendelenburg's position about one hour after surgery while cardiovascular variables were determined...... non-invasively by Modelflow. In Trendelenburg's position, SV (83 ± 19 versus 89 ± 20 ml) and CO (6·2 ± 1·8 versus 6·8 ± 1·8 l/min; both Pheart rate (75 ± 15 versus 76 ± 14 b min(-1) ) and mean arterial pressure were unaffected (84 ± 15 versus 84 ± 16 mmHg). For the 33 patients......, determination of SV and/or CO in Trendelenburg's position can be used to evaluate whether a patient is in need of IV fluid as here exemplified after surgery....

  8. Premature distress of a pavement on expansive black cotton soil in the Horn of Africa

    CSIR Research Space (South Africa)

    Mgangira, Martin B

    2008-11-01

    Full Text Available are generally recognized as expansive soils and change significantly in volume with changes in the moisture condition due to wetting-up and drying-out during the wet and dry seasons respectively. The volume changes lead to differential deformation which...

  9. Expansion Nets and Expansion Processes of Elementary Net Systems

    Institute of Scientific and Technical Information of China (English)

    曹存根

    1995-01-01

    Occurrence nets are insufficient to precisely describe executions of elementary net systems with contacts.Traditionally,S-complementation is used for removal of contacts from the systems.Although the main behavior and properties of the original elementary net systems are preserved during S-complementation,their topologies may be changed greatly.This paper introduces a new kind of nets-expansion nets-for representing behavior of elementary net systems.As shown in the paper,expansion nets are natural as well as sufficient for describing the precise behavior of elementary net systems with or without contactks.

  10. Reed's Conjecture on hole expansions

    CERN Document Server

    Fouquet, Jean-Luc

    2012-01-01

    In 1998, Reed conjectured that for any graph $G$, $\\chi(G) \\leq \\lceil \\frac{\\omega(G) + \\Delta(G)+1}{2}\\rceil$, where $\\chi(G)$, $\\omega(G)$, and $\\Delta(G)$ respectively denote the chromatic number, the clique number and the maximum degree of $G$. In this paper, we study this conjecture for some {\\em expansions} of graphs, that is graphs obtained with the well known operation {\\em composition} of graphs. We prove that Reed's Conjecture holds for expansions of bipartite graphs, for expansions of odd holes where the minimum chromatic number of the components is even, when some component of the expansion has chromatic number 1 or when a component induces a bipartite graph. Moreover, Reed's Conjecture holds if all components have the same chromatic number, if the components have chromatic number at most 4 and when the odd hole has length 5. Finally, when $G$ is an odd hole expansion, we prove $\\chi(G)\\leq\\lceil\\frac{\\omega(G)+\\Delta(G)+1}{2}\\rceil+1$.

  11. Thermal expansion studies of carbon nanotube-reinforced silver nanocomposite

    Energy Technology Data Exchange (ETDEWEB)

    Kumar, Dinesh [Deenbandhu University of Science and Technology, Murthal (India). Dept. of Chemistry; Dyal Singh College Karnal (India). Dept. of Chemistry; Nain, Sonia; Kumar, Ravi [Dyal Singh College Karnal (India). Dept. of Chemistry; Pal, Hemant [Govt. Post Graduate College, Chamba (India). Dept. of Physics

    2015-07-01

    In the present study, a simple and highly effective physical mixing method was used to synthesise carbon nanotube (CNT)-reinforced silver nanocomposites. Composites were prepared with different contents (vol%) of functionalised multiwall nanotubes. The microstructure of synthesised nanocomposites was analysed by X-ray diffraction, electron diffraction spectroscopy, and scanning electron microscopy. Microstructural characterisations revealed good distribution of nanotubes in the silver matrix. The thermal expansion behaviour of the composites was studied in reference to the variation in nanotube volume content in the silver matrix. It was observed that the coefficient of thermal expansion decreased with the increase in the percentage of CNT volume. The thermal expansion of the CNT-reinforced silver composites decreased to 55 % of pure silver upon the introduction of 6 vol% of nanotubes into the silver matrix. The thermal expansion behaviour of the CNT-reinforced silver composites was also analysed theoretically using the rule of mixture and Schapery's model. The CNT-reinforced silver composites may be a promising contact and thermal management material in electronic devices.

  12. Temettü Ödemelerinin Belirleyicileri ve Firma Değeri: Kavramsal Bir Model ve Tahminlemesi

    Directory of Open Access Journals (Sweden)

    Şaban Çelik

    2016-12-01

    Full Text Available Bu çalışmanın amacı temettü politikalarının belirleyicileri ile firma değeri arasındaki ilişkiyi kavramsal bir model çerçevesinde açıklayıp tahminlemesini yapmaktır. Bu kapsamda üç temel hipotez grubu oluşturulup test edilmiştir. Birinci hipotez grubu risk faktörü ile temettü politikaları; ikinci hipotez grubu kurumsal yönetim faktörü ile temettü politikaları ve üçüncü hipotez grubu da temettü polikaları ile firma değeri ilişkisi şeklinde oluşturulmuştur. Birinci ve ikinci hipotez gruplarının test sonuçlarına göre, risk ve kurumsal yönetimin temettü politikaları arasındaki ilişkinin, analiz edilen veri seti ve zaman aralığı kısıtları çerçevesinde red edilmediği görülmüştür. Buna karşın üçüncü hipotez grubu olan temettü politikası ve firma değeri ilişkisi kısmi olarak red edilememiştir.

  13. Pragmatist ve post-Marksist demokratik siyaset anlayışları: Rorty ve Laclau-Mouffe örneği

    OpenAIRE

    KUNDAKÇI, Deniz

    2014-01-01

    Bu tez çalışmasının başlıca hedefi, Rorty ile Laclau ve Mouffe özelinde pragmatizm ve post-Marksizm gibi iki farklı yaklaşımın çağdaş felsefi sorun ve politik tartışmalar etrafında mukayese edilmesi ve mevcut ilişkilerinin ortaya konulmasıdır. Bu bağlamda tezin birinci bölümünde öncelikle Charles Peirce, William James ve John Dewey gibi pragmatist kuramın kurucularının fikirleri hakkında genel bir manzara çizilmektedir. Bu doğrultuda pragmatizmin felsefesi ve onun demokra...

  14. Shengli Making New Progress in Expansion at Overseas Markets

    Institute of Scientific and Technical Information of China (English)

    Yu Ankun

    2001-01-01

    @@ Aiming at its established strategic goal for international operation, Shengli Oilfields made new progress last year in expansion at overseas markets and cooperation with foreign firms. In the fields of contracting projects and providing labor services on the international oil/gas exploration and development market, it has embarked on a higher level of starting point with respect to number of projects,value of investment and volume of engineering.

  15. Structural brain abnormalities correlate with clinical features in patients with drug-naïve OCD: A DARTEL-enhanced voxel-based morphometry study.

    Science.gov (United States)

    Tang, Wanjie; Huang, Xiaoqi; Li, Bin; Jiang, Xiaoyu; Li, Fei; Xu, Jiuping; Yang, Yanchun; Gong, Qiyong

    2015-11-01

    Abnormal brain structure has been reported in obsessive-compulsive disorder (OCD), but findings from these reports have been inconsistent. This study aimed to gain more detailed insights into gray matter structure and correlate this structure with clinical features in patients with drug-naïve OCD using voxel-based morphometry (VBM). Voxel-based morphometry and tools of Diffeomorphic Anatomical Registration through Exponentiated Lie Algebra (DARTEL) were used to investigate structural differences in gray matter volume between 26 drug-naïve OCD patients and 32 healthy controls. Partial correlation analysis was used to analyze associations of gray matter abnormalities with Yale-Brown Obsessive Compulsive Scale (Y-BOCS) scores and illness duration. Compared to healthy controls, drug-naïve OCD patients showed significantly smaller gray matter volume in the right dorsolateral prefrontal cortex (DLPFC), left superior temporal gyrus, left precuneus and right precentral gyrus, as well as significantly greater gray matter volume in the left anterior insula and right parahippocampal gyrus (psuperior temporal gyrus and connected limbic structures such as the parahippocampal gyrus and anterior insula. Longitudinal studies are needed that integrate anatomical, functional and diffusion MRI data. Copyright © 2015 Elsevier B.V. All rights reserved.

  16. Thermal Expansion of Hafnium Carbide

    Science.gov (United States)

    Grisaffe, Salvatore J.

    1960-01-01

    Since hafnium carbide (HfC) has a melting point of 7029 deg. F, it may have many high-temperature applications. A literature search uncovered very little information about the properties of HfC, and so a program was initiated at the Lewis Research Center to determine some of the physical properties of this material. This note presents the results of the thermal expansion investigation. The thermal-expansion measurements were made with a Gaertner dilatation interferometer calibrated to an accuracy of +/- 1 deg. F. This device indicates expansion by the movement of fringes produced by the cancellation and reinforcement of fixed wave-length light rays which are reflected from the surfaces of two parallel quartz glass disks. The test specimens which separate these disks are three small cones, each approximately 0.20 in. high.

  17. Energy efficient perlite expansion process

    Energy Technology Data Exchange (ETDEWEB)

    Jenkins, K.L.

    1982-08-31

    A thermally efficient process for the expansion of perlite ore is described. The inlet port and burner of a perlite expansion chamber (Preferably a vertical expander) are enclosed such that no ambient air can enter the chamber. Air and fuel are metered to the burner with the amount of air being controlled such that the fuel/air premix contains at least enough air to start and maintain minimum combustion, but not enough to provide stoichiometric combustion. At a point immediately above the burner, additional air is metered into an insulated enclosure surrounding the expansion chamber where it is preheated by the heat passing through the chamber walls. This preheated additional air is then circulated back to the burner where it provides the remainder of the air needed for combustion, normally full combustion. Flow of the burner fuel/air premix and the preheated additional air is controlled so as to maintain a long luminous flame throughout a substantial portion of the expansion chamber and also to form a moving laminar layer of air on the inner surface of the expansion chamber. Preferably the burner is a delayed mixing gas burner which materially aids in the generation of the long luminous flame. The long luminous flame and the laminar layer of air at the chamber wall eliminate hot spots in the expansion chamber, result in relatively low and uniform temperature gradients across the chamber, significantly reduce the amount of fuel consumed per unit of perlite expanded, increase the yield of expanded perlite and prevent the formation of a layer of perlite sinter on the walls of the chamber.

  18. Bearing-Mounting Concept Accommodates Thermal Expansion

    Science.gov (United States)

    Nespodzany, Robert; Davis, Toren S.

    1995-01-01

    Pins or splines allow radial expansion without slippage. Design concept for mounting rotary bearing accommodates differential thermal expansion between bearing and any structure(s) to which bearing connected. Prevents buildup of thermal stresses by allowing thermal expansion to occur freely but accommodating expansion in such way not to introduce looseness. Pin-in-slot configuration also maintains concentricity.

  19. Properties of Ettringite Type Expansive Agent

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    By employing different forms and amounts of materials,many kinds of ettringite type expansive agents had been prepared.The relationship between the compositions and properties of expansive agents was analyzed.The design methods of expansive agent have been put forward according to the property requirement of expansive concrete.

  20. 18 CFR 154.309 - Incremental expansions.

    Science.gov (United States)

    2010-04-01

    ... 18 Conservation of Power and Water Resources 1 2010-04-01 2010-04-01 false Incremental expansions... Changes § 154.309 Incremental expansions. (a) For every expansion for which incremental rates are charged... incremental facilities to be rolled-in to the pipeline's rates. For every expansion that has an at-risk...

  1. Caloric Curves and Nuclear Expansion

    CERN Document Server

    Natowitz, J B; Ma, Y; Murray, M; Qin, L; Shlomo, S; Wada, R; Wang, J

    2002-01-01

    Nuclear caloric curves have been analyzed using an expanding Fermi gas hypothesis to extract average nuclear densities. In this approach the observed flattening of the caloric curves reflects progressively increasing expansion with increasing excitation energy. This expansion results in a corresponding decrease in the density and Fermi energy of the excited system. For nuclei of medium to heavy mass apparent densities $~0.3\\rho_0$ are reached at the higher excitation energies. The average densities derived in this manner are in good agreement with those derived using other, more complicated, techniques.

  2. Multipole Expansion in Generalized Electrodynamics

    CERN Document Server

    Bonin, C A; Ortega, P H

    2016-01-01

    In this article we study some classical aspects of Podolsky Electrodynamics in the static regime. We develop the multipole expansion for the theory in both the electrostatic and the magnetostatic cases. We also address the problem of consistently truncating the infinite series associated with the several kinds of multipoles, yielding approximations for the static Podolskian electromagnetic field to any degree of precision required. Moreover, we apply the general theory of multipole expansion to some specific physical problems. In those problems we identify the first terms of the series with the monopole, dipole and quadrupole terms in the generalized theory. We also propose a situation in which Podolsky theory can be experimentally tested.

  3. Thermal Expansion of Irradiated Polytetrafluoroethylene

    OpenAIRE

    Subrahmanyam, HN; Subramanyam, SV

    1987-01-01

    The thermal expansion coefficient of gamma-irradiated Polytetrafluoroethylene (PTFE) has been measured in the temperature range 80-340 K by using a three-terminal capacitance technique. The samples are irradiated in air at room temperature with gamma rays from a $Co^{60}$ source at a dose rate of 0.26 Mrad/h. The change in crystallinity is measured by an x-ray technique. The expansion coefficient is found to increase with radiation dose below 140 K owing to the predominant effect of degradati...

  4. Exact solutions of some physical models using the (′/)-expansion method

    Indian Academy of Sciences (India)

    Anand Malik; Fakir Chand; Hitender Kumar; S C Mishra

    2012-04-01

    The (′/)-expansion method and its simplified version are used to obtain generalized travelling wave solutions of five nonlinear evolution equations (NLEEs) of physical importance, viz. the (2+1)-dimensional Maccari system, the Pochhammer–Chree equation, the Newell–Whitehead equation, the Fitzhugh–Nagumo equation and the Burger–Fisher equation. A variety of special solutions like periodic, kink–antikink solitons, bell-type solitons etc. can easily be derived from the general results. Three-dimensional profile plots of some of the solutions are also drawn.

  5. Removable Type Expansion Bolt Innovative Design

    Science.gov (United States)

    Wang, Feng-Lan; Zhang, Bo; Gao, Bo; Liu, Yan-Xin; Gao, Bo

    2016-05-01

    Expansion bolt is a kind of the most common things in our daily life. Currently, there are many kinds of expansion bolts in the market. However, they have some shortcomings that mainly contain underuse and unremovement but our innovation of design makes up for these shortcomings very well. Principle of working follows this: expansion tube is fixed outside of bolt, steel balls and expansion covers are fixed inside. Meanwhile, the steel balls have 120° with each other. When using it ,expansion cover is moved in the direction of its internal part. So the front part of expansion bolt cover is increasingly becoming big and steel halls is moved outside. Only in this way can it be fixed that steel balls make expansion tube expand. When removing them, expansion bolt is moved outside. So the front part of expansion bolt cover is gradually becoming small and steel balls moves inside, after expansion tube shrinks, we can detach them.

  6. UZMAN VERİ-TABANI SİSTEMLERİ VE ÖNERİLER

    Directory of Open Access Journals (Sweden)

    TALAT FIRLAR

    2003-04-01

    Full Text Available Bu çalışmada uzman sistemler, ilişkisel veri­tabanı sistemleri ve nesneye -dayalı veri-tabanı sistemleri çalışıldı. Dinamik tip, Ad-hoc sorguları ve bildirimselJik , nesneye-dayalı sistemlerde ve uzma n sistemJerde tartışıldı. Prolog ve SQL arasında bir front end tanı mlamak için Arity Prolog ve SQL paketi kullanıldı. Bu proje yeni öneriler belirler.

  7. Ispartada meme kanserli hastalarda BRCA1 ve BRCA2 ekspresyonu

    OpenAIRE

    Çandır, Özden; Karahan, Nermin; Bülbül, Mahmut; Kılınç, Fahriye; Başpınar, Şirin

    2009-01-01

    SüleymanDemirel Üniversitesi TIP FAKÜLTESİ DERGİSİ: 2005 Haziran; 12(2) Ispartada meme kanserli hastalarda BRCA1 ve BRCA2 ekspresyonu Özden Çandır, Nermin Karahan, Mahmut Bülbül, Fahriye Kılınç, Şirin Başpınar, Özet Amaç: BRCA1 ve BRCA2 genlerindeki mutasyonlar, kalıtımsal meme kanserlerinde predispozan faktördür. Sporadik meme kanserlerinde de BRCA proteini ekpresyonunda kayıp olduğu görülmektedir. Bu çalışmada amacımız, Isparta'da meme kanserleri...

  8. The effect of volume expansion with Hydroxyethyl Starch 130/0.4 Solution on perioperative hemodynamics and coagulation function in patients with traumatic brain injury%不同液体预扩容对颅脑外伤患者围术期血流动力学及凝血功能的影响

    Institute of Scientific and Technical Information of China (English)

    何焕钟; 嵇富海

    2011-01-01

    目的:探讨羟乙基淀粉HES130/0.4预扩容对颅脑外伤患者围术期血流动力学及凝血功能的影响.方法:选择40例颅脑外伤需手术治疗的成年患者,随机分为羟乙基淀粉HES130/0.4(观察)组和平衡盐液组.分别在麻醉诱导前20min给予500ml的羟乙基淀粉HES130/0.4和1000ml平衡液,在预扩容前(T0)及预扩容后10 min(T1)、20 min(T2)和颅骨板切开后1 min(T3)、10 min(T4)抽取非输液侧的静脉血2ml用于测定血红蛋白(Hb)、红细胞压积(HCT),计算血容量(BV)、液体潴留量(FR)及容量扩张效率(VEE),并观察血液动力学的变化;在术前,预扩容完成时及术毕3个时点抽取静脉血样测定凝血酶原时间(PT),部分激活的凝血酶原时间(APTT),纤维蛋白原(FIB),D-二聚体及凝血因子Ⅷ活性.结果:预扩容完成后,两组的血流动力学参数比较无显著性差异 (P<0.05);颅骨板切开后1 min、10 min的血流动力学参数观察组明显优于平衡盐液组 (P<0.05);预扩容后20min,留在血管内的液体百分比对照组平均只有41.7%,而观察组为91.2%;两组患者术毕时纤维蛋白原(FIB)值下降同时伴有D-二聚体升高,但两组各时点凝血功能各指标无显著性差异.结论:急诊颅脑外伤患者麻醉前应用500ml羟乙基淀粉HES130/0.4预扩容可维持麻醉诱导及颅骨板切除时的血流动力学稳定,并且对颅脑外伤患者凝血功能无严重影响.%Objective :To investigate the effect of volume expansion with Hydroxyethyl Starch 130/0.4 Solution on perioperative hemodynamics and coagulation function in patients with traumatic brain injury.Methods : 40 patients with head injury required surgery were randomly divided into two groups with 20 cases.each. 1000ml lactated Ringer' s solution (LR) was administered during 20min before general anesthesia in control group, and 500ml 6%hydroxyethylstarch (HES) in study group (HES group). Coagulation studies were performed before the induction of

  9. Raltegravir in treatment naïve patients

    Directory of Open Access Journals (Sweden)

    Cossarini F

    2009-11-01

    Full Text Available Abstract Raltegravir is the first integrase inhibitor approved for the treatment of HIV infection based on the superior efficacy it showed compared to optimized backbone therapy alone in patients harboring multidrug resistant viruses. Studies on naïve patients showed comparable efficacy of raltegravir and efavirenz and just recently the US Food and Drug Administration (FDA approved raltegravir for the use in naïve patients based on the favorable results of the international double-blind phase III STARTMRK trial. Additional interesting findings were the faster, and not yet explained, decay of HIV-1 RNA and the higher CD4+ cells increase in the raltegravir group as compared to the efavirenz group. Raltegravir is generally well tolerated and adverse events were generally similar in raltegravir and comparator arms throughout all studies. When compared to efavirenz, patients on raltegravir showed less incidence of central nervous system-related adverse events. In studies on experienced patients higher incidence of cancers was found in the raltegravir arm: a relationship with the drug was, however not confirmed in a recent review considering all raltegravir studies. Raltegravir also showed a safe lipid profile expecially in naïve patients, finding that renders the drug attractive for patients with other cardiovascular risk factors. All this characteristics in association with its specific mechanism of action, make raltegravir an interesting drug for naïve patients and a large use in this type of patients is predictable. Only time and experience, however, will tell us whether raltegravir will maintain its promises in the long run.

  10. Histone deacetylase complexes promote trinucleotide repeat expansions.

    Directory of Open Access Journals (Sweden)

    Kim Debacker

    2012-02-01

    Full Text Available Expansions of DNA trinucleotide repeats cause at least 17 inherited neurodegenerative diseases, such as Huntington's disease. Expansions can occur at frequencies approaching 100% in affected families and in transgenic mice, suggesting that specific cellular proteins actively promote (favor expansions. The inference is that expansions arise due to the presence of these promoting proteins, not their absence, and that interfering with these proteins can suppress expansions. The goal of this study was to identify novel factors that promote expansions. We discovered that specific histone deacetylase complexes (HDACs promote CTG•CAG repeat expansions in budding yeast and human cells. Mutation or inhibition of yeast Rpd3L or Hda1 suppressed up to 90% of expansions. In cultured human astrocytes, expansions were suppressed by 75% upon inhibition or knockdown of HDAC3, whereas siRNA against the histone acetyltransferases CBP/p300 stimulated expansions. Genetic and molecular analysis both indicated that HDACs act at a distance from the triplet repeat to promote expansions. Expansion assays with nuclease mutants indicated that Sae2 is one of the relevant factors regulated by Rpd3L and Hda1. The causal relationship between HDACs and expansions indicates that HDACs can promote mutagenesis at some DNA sequences. This relationship further implies that HDAC3 inhibitors being tested for relief of expansion-associated gene silencing may also suppress somatic expansions that contribute to disease progression.

  11. Regulation of gas infrastructure expansion

    NARCIS (Netherlands)

    De Joode, J.

    2012-01-01

    The topic of this dissertation is the regulation of gas infrastructure expansion in the European Union (EU). While the gas market has been liberalised, the gas infrastructure has largely remained in the regulated domain. However, not necessarily all gas infrastructure facilities – such as gas storag

  12. On persistently positively expansive maps

    Directory of Open Access Journals (Sweden)

    Alexander Arbieto

    2010-06-01

    Full Text Available In this paper, we prove that any C¹-persistently positively expansive map is expanding. This improves a result due to Sakai (Sakai 2004.Neste artigo, mostramos que todo mapa C¹-persistentemente positivamente expansivo e expansor. Isto melhora um resultado devido a Sakai (Sakai 2004.

  13. On Fourier re-expansions

    OpenAIRE

    Liflyand, E.

    2012-01-01

    We study an extension to Fourier transforms of the old problem on absolute convergence of the re-expansion in the sine (cosine) Fourier series of an absolutely convergent cosine (sine) Fourier series. The results are obtained by revealing certain relations between the Fourier transforms and their Hilbert transforms.

  14. Large N Expansion. Vector Models

    CERN Document Server

    Nissimov, E; Nissimov, Emil; Pacheva, Svetlana

    2006-01-01

    Preliminary version of a contribution to the "Quantum Field Theory. Non-Perturbative QFT" topical area of "Modern Encyclopedia of Mathematical Physics" (SELECTA), eds. Aref'eva I, and Sternheimer D, Springer (2007). Consists of two parts - "main article" (Large N Expansion. Vector Models) and a "brief article" (BPHZL Renormalization).

  15. Grounding Naïve Physics and Optics in Perception

    Directory of Open Access Journals (Sweden)

    Ivana Bianchi

    2014-12-01

    Full Text Available Many adults hold mistaken beliefs concerning the behavior of mechanical motion and reflections. In the field of psychology this has been investigated in the areas of naïve physics and naïve optics. The interesting question regards where these false beliefs come from. Particularly thought-provoking is the case of errors which are at odds not only with (presumably or even actually known physical/optical concepts, but also with what people would actually perceive. Some errors are in fact consistent with what people see in ecological conditions while others apparently are not. This has led to the former being referred to as perceptual errors and the latter as conceptual errors (Lawson and Bertamini 2006. We propose that many of these ‘conceptual errors’ are generalizations of what can be actually perceived under some conditions that are then incorrectly applied under others. In this sense, they can be thought of as a second way in which perception shapes naïve beliefs.

  16. Effective Expansion: Balance between Shrinkage and Hygroscopic Expansion.

    Science.gov (United States)

    Suiter, E A; Watson, L E; Tantbirojn, D; Lou, J S B; Versluis, A

    2016-05-01

    The purpose of this study was to investigate the relationship between hygroscopic expansion and polymerization shrinkage for compensation of polymerization shrinkage stresses in a restored tooth. One resin-modified glass-ionomer (RMGI) (Ketac Nano, 3M ESPE), 2 compomers (Dyract, Dentsply; Compoglass, Ivoclar), and a universal resin-based composite (Esthet•X HD, Dentsply) were tested. Volumetric change after polymerization ("total shrinkage") and during 4 wk of water storage at 37°C was measured using an optical method (n= 10). Post-gel shrinkage was measured during polymerization using a strain gauge method (n= 10). Extracted human molars with large mesio-occluso-distal slot preparations were restored with the tested restorative materials. Tooth surfaces at baseline (preparation), after restoration, and during 4 wk of 37°C water storage were scanned with an optical scanner to determine cuspal flexure (n= 8). Occlusal interface integrity was measured using dye penetration. Data were analyzed using analysis of variance and post hoc tests (significance level 0.05). All tested materials shrunk after polymerization. RMGI had the highest total shrinkage (4.65%) but lowest post-gel shrinkage (0.35%). Shrinkage values dropped significantly during storage in water but had not completely compensated polymerization shrinkage after 4 wk. All restored teeth initially exhibited inward (negative) cuspal flexure due to polymerization shrinkage. Cuspal flexure with the RMGI restoration was significantly less (-6.4 µm) than with the other materials (-12.1 to -14.1 µm). After 1 d, cuspal flexure reversed to +5.0 µm cuspal expansion with the RMGI and increased to +9.3 µm at 4 wk. After 4 wk, hygroscopic expansion compensated cuspal flexure in a compomer (Compoglass) and reduced flexure with Dyract and resin-based composite. Marginal integrity (93.7% intact restoration wall) was best for the Compoglass restorations and lowest (73.1%) for the RMGI restorations. Hygroscopic

  17. The Digital Exhibition and Keyimage Ontology / Dijital Sergiler ve Anahtar Resim Ontolojisi

    Directory of Open Access Journals (Sweden)

    Mícheál Mac an Airchinnigh

    2008-04-01

    Full Text Available [English abstract]The Age of Image predates and is currently contemporaneous with the Information Age. In our times the explosive expansion of Web 2.0 Social Space, typified by the phenomena of De.licio.us, Flickr, MySpace, YouTube…, and the concomitant emergence of folksonomy, present interesting challenges in the management of this information. One key process by which to accomplish this in Social Space, is the wedding of folksonomy (of the people with ontology (of the machine. Such a wedding must necessarily be conducted in the shared physicality of the word, of language. In this respect, WordNet together with OWL, play the role of matchmaker. But the same Social Space also provides an opportunity for natural folksonomical tagging by digiFoto (keyimage. The research harness for experimental keyimage tagging consists of Flickr as the main (digiFoto image Social Space testbed and De.licio.us as the auxillary outreach secondary Social Space. Protégé Editor with OWL-DL provides the support for the bridge from keyimage to the formal ontology. The primary end user application domain is the keyimage tagging of paintings in an online art gallery.[Turkish abstract]Görüntü Çağı, Bilgi Çağından önce gelir ve günümüzde Bilgi Çağıyla çağdaştır. De.licio.us, Flickr, MySpace, YouTube. . . gibi olgularla örneklenen Web 2.0 Sosyal Uzayının tahminlerin ötesinde büyümesi ve bununla birlikte ortaya çıkan etiketleme bilgi yönetiminde ilginç gelişmelere sahne olmaktadır. Sosyal Uzayda bilgi yönetimini başarmak (insanlar tarafından gerçekleştirilen etiketleme ve (makineler tarafından gerçekleştirilen ontolojinin birleştirilmesini gerektirmektedir. Böyle bir birleştirme mutlaka sözün ve dilin ortak fizikselliğiyle gerçekleştirilmelidir. Bu hususta Web Ontoloji Dili (OWL ile WordNet çöpçatan rolü oynarlar. Öte yandan aynı Sosyal Uzay dijiFoto (anahtar resimle doğal folksonomik işaretleme yapmak için de bir

  18. Reduced-Volume Fracture Toughness Characterization for Transparent Polymers

    Science.gov (United States)

    2015-03-21

    the coefficient of thermal expansion α, and the specific heat capacity at a constant volume Cv, respectively. The functions f1−4 are relaxation...relaxation functions are either related to volumetric quantities (bulk modulus, coefficient of thermal expansion , and specific volumetric heat capacity) or a...product of the bulk modulus and the coefficient of thermal expansion is expressed as L = Kα, and ε dev is the deviatoric part of the integrated rate

  19. The average free volume model for liquids

    CERN Document Server

    Yu, Yang

    2014-01-01

    In this work, the molar volume thermal expansion coefficient of 59 room temperature ionic liquids is compared with their van der Waals volume Vw. Regular correlation can be discerned between the two quantities. An average free volume model, that considers the particles as hard core with attractive force, is proposed to explain the correlation in this study. A combination between free volume and Lennard-Jones potential is applied to explain the physical phenomena of liquids. Some typical simple liquids (inorganic, organic, metallic and salt) are introduced to verify this hypothesis. Good agreement from the theory prediction and experimental data can be obtained.

  20. Diş hekimliğinde estetik ve renk

    Directory of Open Access Journals (Sweden)

    Erkut Kahramanoğlu

    2012-01-01

    Full Text Available

    Color science and art should be understood to overcome the difficulties related to the color selection at aesthetic restorative dentistry. Closely matching natural teeth with an artificial restoration can be one of the most challenging procedures in restorative dentistry. Concerning dental ceramic techniques, the principles of light and color is important for the preparation of restorations compatible with the natural color of teeth. Color determination in dentistry can be divided 2 categories: visual and instrumental. Determination of tooth color by visual means is considered highly subjective. Computer aided systems give more objective results than subjective visual examination. For that reason, both visual and instrumental shade matching systems should be used together. This article reviews the scientific principles of color and the factors involved in shade selection for prosthetic teeth.

    Keywords: Color, color selection systems, esthetic, color selection.

     

    ÖZET

    Estetik restoratif diş hekimliğinde renk seçimi ile ilgili zorlukların üstesinden gelebilmek için, renk bilimi ve sanatını anlamak gerekir. Restoratif diş hekimliğinin en zor prosedürlerinden biri doğal dişlere uyumlu bir restorasyonun yapılmasıdır. Diş hekimliği seramiğini ilgilendiren tekniklerin, ışık ve renk prensiplerinin bilinmesi doğal dişlerle uyumlu renkte restorasyonlar hazırlanabilmesi için önemlidir. Diş hekimliğinde renk belirlenmesi; görsel ve bilgisayar destekli cihazlar yardımı ile olmak üzere iki kategoriye ayrılabilir. Diş renginin göz ile değerlendirilmesi oldukça sübjektiftir. Bilgisayar destekli cihazların kullanımı sübjektif olan görsel değerlendirmeye kıyasla daha objektif sonuçlar ortaya koymaktadır. Görsel ve bilgisayar destekli sistemlerin kombine olarak kullanımı önerilmektedir.  Bu makale, rengin bilimsel esaslarını ve

  1. sLORETA intracortical lagged coherence during breath counting in meditation-naïve participants

    Directory of Open Access Journals (Sweden)

    Patricia eMilz

    2014-05-01

    Full Text Available We investigated brain functional connectivity comparing no-task resting to breath counting (a meditation exercise but given as task without referring to meditation. Functional connectivity computed as EEG coherence between head-surface data suffers from localization ambiguity, reference dependence, and overestimation due to volume conduction. Lagged coherence between intracortical model sources addresses these criticisms. With this analysis approach, experienced meditators reportedly showed reduced coherence during meditation, meditation-naïve participants have not yet been investigated. 58-channel EEG from 23 healthy, right-handed, meditation-naïve males during resting [3 runs] and breath counting [2 runs] was computed into sLORETA time series of intracortical electrical activity in 19 regions of interest corresponding to the cortex underlying 19 scalp electrode sites, for each of the 8 independent EEG frequency bands covering 1.5-44 Hz. Intracortical lagged coherences and head-surface conventional coherences were computed between the 19 regions/sites. During breath counting compared to resting, paired t-tests corrected for multiple testing revealed 4 significantly lower intracortical lagged coherences, but 4 significantly higher head-surface conventional coherences. Lowered intracortical lagged coherences involved left BA 10 and right BAs 3, 10, 17, 40. In conclusion, intracortical lagged coherence can yield results that are inverted to those of head-surface conventional coherence. The lowered functional connectivity between cognitive control areas and sensory perception areas during meditation-type breath counting compared to resting conceivably reflects the attention to a bodily percept without cognitive reasoning. The reductions in functional connectivity were similar but not as widespread as the reductions reported during meditation in experienced meditators.

  2. MONSOONS MUDE AND GOLD MUSONLAR GEMİ VE ALTIN

    Directory of Open Access Journals (Sweden)

    Paul LUNDE

    2009-12-01

    Full Text Available The “global economy” of the Middle Ages was created by linking the Indian Ocean trading networks with those of the Mediterranean Sea and its African and European hinterlands. These products, together with ceramics, textiles and sugar provided from Egypt and Syria, reached European markets almost exclusively through the Italian maritime republics of Amalfi, Pisa, Genoa and Venice. Especially the direction of the monsoon winds in the Indian Ocean and the course of the Venice trade ships were at the same direction. Thereby, Venice trade ships set out toward the end of August and made their way slowly through the Adriatic and the Aegean to Cyprus and Alexandria, timing their arrival there to coincide with the availability of monsoon-borne and by this way the products which are ned carried through Europe. İt is important to emphasize this subject that North Europe economy depends on this Monsoons where they became at Indian Ocean. As a maritime republic dedicated itself to the international trade, Venice was an anomaly in a feudal Europe that measured wealth by land, not money. Therefor this idea were encouraging their believing about ending the monopoly of the Muslim trade at the Indian Ocean. Ortaçağın global ekonomisini Hint Okyanusu ticaret hattı ile Akdeniz, Afrika ve Avrupa Hinterlantları arasındaki ticaret bağlantısı teşkil ediyordu. Avrupa ekonomisindeki gelişmelere paralel olarak Batı dünyasının gereksinim duyduğu ve Mısır ile Suriye’den tedarik edilen şeker, tekstil, seramik gibi ürünler Amalfi, Pisa, Ceneviz ve Venedik gibi İtalyan Cumhuriyetleri aracılığıyla Avrupa pazarlarına taşınmaktaydı. Özellikle Hint Okyanusu üzerindeki muson rüzgârlarının yönleriyle Venedik ticaret gemilerinin rotaları aynı doğrultudaydı. Bu suretle Ağustos ayının sonuna doğru İtalya’dan ayrılan gemiler, Adriyatik, Ege ve Kıbrıs rotasından İskenderiye’ye ulaştığı esnada musonlarla kar

  3. J�ABİRENT ROBOTU TASARIMI VE UYGULAMASI

    Directory of Open Access Journals (Sweden)

    ALİ ÇETİNER

    2003-12-01

    Full Text Available Robotlar, gerek otomasyon sistemlerinde gerekse de günlülk yaşantımızın çeşitli alanlarında güıı geçtikçe daha geniş bir şekilde kullanı lmaktadır. Ço k farklı alanlard� çeşitli işleınıeri gerçekleştirmek için kulJanılan robotlarda kontrol işlemi, mikroişlemciler veya nıikrodenetleyiciler ile gerçekleştir ilmektedir. Robot uygu lamal:arında, mikroişlemci ile birlikte çevre biriml erini içermesi nedeni ile nukrodenetl ey icilerin kullanıını tercih edilmektedir. Bu çalışınada, miikrodenetleyici kontrollü yürüyen bir robotun tasarıımı ile ilgili detaylar verilmekte ve tasarlanan robotun gerçekleşmesi ile ilgili açıklan1alar ve rilrı:ıcktedir. • Iki step motor kullanılarak oluşturulan iki tekerlekli robot, PIC16F84 mikro denetleyicisi kullanılarak kontrol edi int ektedi r. Tasarlanan ve gerçekleşti rilen sistemde 3 temel devre bulunmaktadır. PIC16F84 kullanılarak oluşturulan kontrol devresi, :algılayıcı devresi ve PIC16F84 temelli step motor sürücü devresi. Uygulanıası yapılan robotta, yansıtıcı yüzeylere duyarlı algılayıc ılardan gelen bilgiler doğrultusunda robot yönünü ve hareketini belirlenıektcdir. Algıla yıcılardan gelen bilgiler, kontrol devre sindeki PIC16F84 mikrodenetleyici s i tarafından yorumlanmakta ve PIC16F84'de bulunan progran:ı yardımı ile step motorlar sürülerck motorun hareketi sa ğlanma ktadı r. Hareket edebilme kabiliyeti kazanan robot, labirentin duvarlarındaki yansıtıcı yüzeyleri dikkate alarak yönünü tayin edebilmekte ve robotun labirent içindeki h areket leri , kontrol devresindeki PIC16F84'e yüklenen programa göre gerçekleştirilmektedir.

  4. Ectopic expression of a Ve homolog VvVe gene from Vitis vinifera enhances defense response to Verticillium dahliae infection in tobacco.

    Science.gov (United States)

    Tang, Juan; Lin, Jing; Yang, Yuwen; Chen, Tianzi; Ling, Xitie; Zhang, Baolong; Chang, Youhong

    2016-01-15

    Verticillium wilt is a soil borne disease that can cause devastating losses to the production of many economically important crops. A Ve1 homologous gene responding to Verticillium dahliae infection was identified in Vitis vinifera cv. "HeiFeng" by semi-quantitative reverse transcription polymerase chain reaction and was designated as VvVe. The overexpression of VvVe in transgenic Nicotiana benthamiana plants significantly enhanced the resistance to isolate V991 of V. dahliae when compared with the wild type plants. The expressions of defense-related genes including the salicylic acid regulated gene pathogen-related 1 (PR1) but not PR2, the ethylene- and jasmonic acid-regulated genes ethylene response factor 1 (ERF1) and lipoxygenase (LOX) were significantly increased due to over expression of VvVe. And greater accumulation of active oxygen, callose and phenylalanine-ammonia lyase were observed in the leaves of transgenic VvVe tobacco plants than the wild type when under infection by V. dahliae. Moreover, the hypersensitive response mimicking cell death was exclusively occurred in the transgenic VvVe tobacco plants but not in the wild type. Taken together, the VvVe gene is a Ve1 like gene which involves in the signal cascade of salicylic acid, jasmonate, and ethylene defense pathways and enhances defense response to V. dahliae infection in the transgenic tobacco. Copyright © 2015 Elsevier B.V. All rights reserved.

  5. Generalized Grüneisen parameters and low temperature limit of lattice thermal expansion of cadmium and zirconium

    Indian Academy of Sciences (India)

    S Sindhu; C S Menon

    2006-09-01

    The generalized Grüneisen parameters ($_{j}^{'}$) and ($_{j}^{''}$) for cadmium and zirconium were calculated from the second- and third-order elastic constants to determine the low temperature limit of the volume thermal expansion of these metals of hexagonal symmetry. The low temperature limit of cadmium and zirconium was calculated to be positive values indicating a positive volume expansion down to 0 K even though many Grüneisen gammas were found to be negative.

  6. Gerze Horoz ve Tavuklarında Larynx, Trachea ve Syrinx’in Anatomik Yapısının Belirlenmesi

    Directory of Open Access Journals (Sweden)

    Burcu ONUK

    2015-01-01

    Full Text Available Çalışma materyalini Karadeniz Bölgesinde yer alan Sinop İli’nin Gerze İlçe’sine ait yerel bir ırk olan ve bu yörede ötüşüyle ve görünümüyle tanınan Gerze horozu ve tavuğu oluşurdu. Larynx, trachea ve syrinx’in incelendiği bu çalışmada 7 erkek ve 7 dişi olmak üzere toplam 14 hayvan kullanıldı. Larynx’in kıkırdaklarını tek olan cartilago cricoidea, cartilago procricoidea ve çift olan cartilago arytenoidea oluşturdu. Erkeklerdeki glottis genişliğinin (3,54±0,37 dişilerdekinden (1,35±0,42 fazla olduğu dikkat çekti. Dış larynx kasları m. cricohyoideus, m. cleidotrachealis ve m. tracheolateralis, iç larynx kasları ise m. dilator glottidis ve m. consrictor glottidis olarak belirlendi. Trachea 112-117 adet tam daire şeklindeki kıkırdak halkadan oluştu. Gerze horoz ve tavuklarında syrinx tracheobronchial tipti. Syrinx’in oluşumuna katılan cartt. tracheosyringeales’in 12-13 adet kıkırdak halkadan oluştuğu gözlendi. Bunlardan cranial’deki 8-9 adet kıkırdak halka tympanum’u oluşturdu. Diğerlerinin ise daha ince ve yassı olduğu ve membrana tympaniformis lateralis’in içinde gömülü olarak bulunduğu saptandı. Yandan kama biçiminde görünen pessulus, dorsal ve ventral’den ise ikizkenar üçgen şeklinde idi. Sonuç olarak, diğer kuş türleri ile farklılıkları bulunan Gerze horoz ve tavuğunun larynx, trachea ve syrinx’inin genel olarak evcil kanatlılarla benzerlik gösterdiği belirlendi.

  7. Olgunlaşma Döneminin Kinoa (Chenopodium quinoa Willd.)’da Ot Verimi ve Kalitesi ile Gaz ve Metan Üretimine Etkisi

    OpenAIRE

    KAPLAN, Mahmut; ÜKE, Özlem; KALE, Hasan; KAMALAK, Adem

    2016-01-01

    Çalışmanın amacı farklı olgunlaşma dönemlerinde (çiçeklenme öncesi, tam çiçeklenme ve tohum bağlama) hasat edilen kinoa bitkisinin (Chenopodium quinoa Willd.) yeşil ve kuru ot verimi, besleme değeri, in vitro gaz ve metan üretimi, metabolik enerji (ME) ve organik madde sindirim derecesine (OMS) etkisini belirlemektir. Kinoa bitkisinin olgunlaşması araştırmada incelenen tüm parametreleri etkilemiştir (P≤0.01). Çalışma sonuçlarına göre olgunlaşma döneminin ilerlemesiyle yeşil ve kuru ot verimle...

  8. Exponential Expansion in Evolutionary Economics

    DEFF Research Database (Denmark)

    Frederiksen, Peter; Jagtfelt, Tue

    2013-01-01

    concepts are described in detail. Taken together it provides the rudimentary aspects of an economic system within an analytical perspective. It is argued that the main dynamic processes of the evolutionary perspective can be reduced to these four concepts. The model and concepts are evaluated in the light...... of Thomas Kuhn’s notion of scientific paradigms and criteria for a good theory (1977, 1996). The paper thus aims to augment and assimilate the fragmented and scattered body of concepts presently residing within the field of evolutionary economics, by presenting an intuitive framework, applicable within...... to this problem is proposed in the form of a model of exponential expansion. The model outlines the overall structure and function of the economy as exponential expansion. The pictographic model describes four axiomatic concepts and their exponential nature. The interactive, directional, emerging and expanding...

  9. In vitro methods for generating CD8+ T-cell clones for immunotherapy from the naïve repertoire.

    Science.gov (United States)

    Ho, William Y; Nguyen, Hieu N; Wolfl, Matthias; Kuball, Juergen; Greenberg, Philip D

    2006-03-20

    Innovations in gene discovery and the analysis of gene expression are facilitating the identification of a growing number of antigens that could potentially be targeted for immunotherapy of tumors. Methods to reliably generate antigen-specific T-cell responses in vitro would be useful not only to screen candidate antigens for immunogenicity prior to embarking on in vivo vaccination trials, but also to generate T-cell lines or clones that could be used directly for adoptive immunotherapy approaches. Although many techniques have proven successful for expanding ex vivo effector cells from antigen-specific memory CD8(+) cells that have been primed in vivo, methods to reliably generate high-avidity CTL clones from the naïve repertoire have not been well described. Various methods for the induction and expansion of antigen-specific CD8(+) CTL clones from healthy A2(+) donors were compared, using WT1 as a model tumor-associated antigen for which there is a low frequency of precursor T cells in naïve individuals. In contrast to the well-studied Melan-A/MART-1 (Melan-A) A2-restricted response, for which the CD8(+) T-cell precursor frequency in the naïve repertoire is unusually high, successful expansion of WT1-specific CD8(+) T cells appeared to be more dependent upon cell culture conditions. In particular, primary stimulation with autologous peptide-loaded monocyte-derived DC generated in 48 h (DC2d) was more effective in expanding WT1-reactive populations of CTL than stimulation with DC generated using the more standard week-long protocol (DC7d). Adding supplemental IL-7 2 to 3 days after initiation of a stimulation cycle expanded antigen-specific cells within CTL lines more efficiently than including the cytokine from the beginning of the cycle. Following primary stimulation with peptide-loaded mature DC, subsequent restimulation with peptide-loaded PBMC as the stimulators was more effective at expanding antigen-specific cells than repeated stimulation with mature DC

  10. Sıcak uyaran karşısında zirkonyum ve cam fiber ile güçlendirilmiş kompozit post sistemlerde ve diş dokularında oluşan termal streslerin karşılaştırmalı olarak incelenmesi

    Directory of Open Access Journals (Sweden)

    Levent Nalbant

    2012-04-01

    Full Text Available Objectives: The oral cavity is subjected to thermal irritation from hot and cold foods and beverages. Thermal irritation in the oral cavity produces expansions and contractions in restorative materials. This study investigates that, the effect of thermal stress and temperature distribution when 65 C° thermal load was applied on glass fiber reinforced composite resin post and zirconia post in right maxillary canine by three dimensional finite element method.
    Materials and Methods: Right maxillary canine, full ceramic crown, composite core material, luting agent, post materials, the ledge for ferrule effect, gutta percha, compact and spongious bone that surround the tooth were modeled for the thermal stress analysis. 65 C° thermal load was applied on the model for 5 secs. Temperature and thermal stresses were determined on the bucco lingual section of the model on 7 points. Besides, max. thermal stresses on the nodes and their values were determined.
    Results: Zirconia post systems produced more temperature and thermal stresses on the restorative materials, tooth structures and posts than glass fiber reinforced composite resin posts. Thermal stresses were much more between the layers of restorative materials, on the luting agent and cervical region. Thermal stresses were determined near the cervical region of the model on root dentin, compact and spongious bone regions and no stresses were determined on the middle and apical third of the model. Both two post materials have close-range values of about the temperature and thermal stress distributions.
    Conclusions: Generally, zirconia post generated more heat and thermal stresses on the tooth structures, the other restorative materials and the post itself.
    Key Words: Zirconia post, glass fiber reinforced composite resin post, thermal stress analysis.

    ÖZET
    Amaç: Ağıza alınan soğuk – sıcak yiyecekler ve içecekler nedeniyle oral kavite termal bir

  11. Multiscale expansions in discrete world

    Indian Academy of Sciences (India)

    Ömer Ünsal; Filiz Taşcan; Mehmet Naci Özer

    2014-07-01

    In this paper, we show the attainability of KdV equation from some types of nonlinear Schrödinger equation by using multiscale expansions discretely. The power of this manageable method is confirmed by applying it to two selected nonlinear Schrödinger evolution equations. This approach can also be applied to other nonlinear discrete evolution equations. All the computations have been made with Maple computer packet program.

  12. College Expansion and Curriculum Choice

    OpenAIRE

    Kaganovich, Michael; Su, Xuejuan

    2012-01-01

    This paper analyzes the impact of college enrollment expansion on student academic achievements and labor market outcomes in the context of competition among colleges. When public policies promote “access” to college education, colleges adjust their curricula: Less selective public colleges adopt a less demanding curriculum in order to accommodate the influx of less able students. As we argue in the paper, this adjustment benefits low-ability college students at the expense of those of medium...

  13. RELIABILITY OF LENTICULAR EXPANSION COMPENSATORS

    Directory of Open Access Journals (Sweden)

    Gabriel BURLACU,

    2011-11-01

    Full Text Available Axial lenticular compensators are made to take over the longitudinal heat expansion, shock , vibration and noise, made elastic connections for piping systems. In order to have a long life for installations it is necessary that all elements, including lenticular compensators, have a good reliability. This desire can be did by technology of manufactoring and assembly of compensators, the material for lenses and by maintenance.of compensator

  14. Topological expansion and boundary conditions

    CERN Document Server

    Eynard, Bertrand

    2008-01-01

    In this article, we compute the topological expansion of all possible mixed-traces in a hermitian two matrix model. In other words we give a recipe to compute the number of discrete surfaces of given genus, carrying an Ising model, and with all possible given boundary conditions. The method is recursive, and amounts to recursively cutting surfaces along interfaces. The result is best represented in a diagrammatic way, and is thus rather simple to use.

  15. Multiple scattering expansion with distortion

    Science.gov (United States)

    Tandy, P. C.; Thaler, R. M.

    1980-12-01

    A multiple scattering description of elastic scattering is formulated in terms of impulsive scatterings from single target nucleons and pairs of target nucleons. In this description, distortion effects on the projectile from the residual medium are also described by multiple scattering in terms of the same single and pair amplitudes. At the level of single scattering, this procedure yields the first order optical potential result of Kerman, McManus, and Thaler. When scattering from both single nucleons and pairs of nucleons is included, the method leads to a one-body integral equation which requires the physical projectile-nucleon and projectile-pair transition amplitudes as input. This input is similar, but not exactly equivalent to that required by the spectator expansion for the optical potential truncated at second order. A principal advantage of the present formulation is that there need be no explicit dependence upon the projection operator Q which projects off the target ground state. This feature introduces a scaling which appears to be a direct extension of the first order Kerman, McManus, and Thaler type of scaling. We follow up suggestions arising in the foregoing to show that the exact optical potential to second order in the spectator expansion can also be cast into a form having no explicit dependence upon Q, and requiring physical projectile-nucleon and projectile-pair transition amplitudes as input. NUCLEAR REACTIONS Multiple scattering from single nucleons, pairs of nucleons in nucleus. Distortion from residual medium. Optical potential. spectator expansion.

  16. Urban underground network expansion planning

    Energy Technology Data Exchange (ETDEWEB)

    Bozic, Z. [Sinclair Knight Merz Pty Ltd., Perth (Australia); Hobson, E. [HI Consulting Services Pty Ltd., Adelaide (Australia)

    1997-03-01

    The authors describe a three step approach to expansion planning of high voltage (HV) urban underground distribution networks. Although the techniques are specifically oriented to underground systems, they are equally applicable to overhead system design. The fundamental engineering problem is how to connect individual high voltage to low voltage substations (HV/LV SS) and zone HV SS into a future urban underground network. The problem is to rearrange the HV network to minimise the cost of expansion subject to provision of an alternative supply, specified load transfer among the neighbouring zone SS, and other general planning constraints such as feeder capacity, voltage regulation, operational requirements and losses. A review of the current state of the art of distribution expansion planning is provided. The normal manual approach is discussed together with more recent research into computer methods. Three lines of computer research are identified and classified as radially constrained, security constrained and utilisation of travelling salesman/vehicle routing problem algorithms (TSP/VRP). The TSP/VRP line of research has been extended here to produce practical techniques for the assistance of network planners. (Author)

  17. 78 FR 36165 - Reorganization/Expansion of Foreign-Trade Zone 104; (Expansion of Service Area and Expansion of...

    Science.gov (United States)

    2013-06-17

    ... Federal Register (77 FR 43047, 07/23/12) and the application has been processed pursuant to the FTZ Act... Foreign-Trade Zones Board Reorganization/Expansion of Foreign-Trade Zone 104; (Expansion of Service Area and Expansion of Zone); Under Alternative Site Framework, Savannah, Georgia Pursuant to its...

  18. Modelling The Effects of Aggregate Size on Alkali Aggregate Reaction Expansion

    Directory of Open Access Journals (Sweden)

    N. Z. Sekrane

    2014-06-01

    Full Text Available This work aims at developing models to predict the potential expansion of concrete containing alkali-reactive aggregates. The paper gives measurements in order to provide experimental data concerning the effect of particle size of an alkali-reactive siliceous limestone on mortar expansion. Results show that no expansion was measured on the mortars using small particles (0.5-1.0 mm while the particles (1.0–2.0 mm gave the largest expansions (0.217%. Two models are proposed, the first one studies the correlations between the measured expansions and the size of aggregates, the second one calculates the thickness of the porous zone necessary to take again all the volume of the gel created.

  19. Study on a New Type of Jet Pressurization Evaporation Expansion Apparatus

    Institute of Scientific and Technical Information of China (English)

    Chen Boyi; Zhang Mingxin; Yang Li

    2001-01-01

    The volume expansion of the stuff (e. g. tobacco stem) is of great importance to an increase in the product quality and a decrease in the production cost. This paper puts forward the basic configuration and the expansion mechanism of a new type of jet pressurization evaporation expansion apparatus. By the thermodynamic calculation of the apparatus, we give variations in steam pressure on various cross sections of the flow system for the apparatus,manufacture a sample machine, and finish run tests of the machine. The test results show that the apparatus may make the relative increase in fill value of tobacco stem higher than 75%, and may cause the steam consumption required in the expansion process of each kilogram stem to reduced about 40% compared with conventional expansion apparatus. Additionally, the configuration of the apparatus is simple and small, its cost of manufacture is very low, and both its operation and maintenance are extremely convenient.

  20. Determination of effective thermal expansion coefficients of unidirectional fibrous nanocomposites

    Science.gov (United States)

    Dai, Ming; Schiavone, Peter; Gao, Cun-Fa

    2016-10-01

    We present an efficient numerical scheme (based on complex variable techniques) to calculate the effective thermal expansion coefficients of a composite containing unidirectional periodic fibers. Moreover, the mechanical behavior of the fibers incorporates interface effects allowing the ensuing analytical model of the composite to accommodate deformations at the nanoscale. The resulting `nanocomposite' is subjected to a uniform temperature variation which leads to periodic deformations within the plane perpendicular to the fibers and uniform deformations along the direction of the fibers. These deformation fields are determined by analyzing a representative unit cell of the composite subsequently leading to the corresponding effective thermal expansion coefficients. Numerical results are illustrated via several physical examples. We find that the influence of interface effects on the effective thermal expansion coefficients (in particular that corresponding to the transverse direction in the plane perpendicular to the fibers) decays rapidly as the fibers become harder. In addition, by comparing the results obtained here with those from effective medium theories, we show that the latter may induce significant errors in the determination of the effective transverse thermal expansion coefficient when the fibers are much softer than the matrix and the fiber volume fraction is relatively high.

  1. Thermal expansion of ceramics around room temperature

    OpenAIRE

    橋本, 忍; 安達, 信泰; 太田, 敏孝; 宮崎, 英敏; ハシモト, シノブ; アダチ, ノブヤス; オオタ, トシタカ; Hashimoto, Shinobu; Adachi, Nobuyasu; Ota, Toshitaka

    2010-01-01

    Thermal expansion of some ceramics, polymers and metals was measured by dilatometer around room temperature (from -140℃to +200℃), and compared with thermal expansion in the high temperature region. The CTE (coefficient of thermal expansion)of almost ceramics changed drastically between room temperature and high temperature region. On the other hand, the CTE ofmetals did not change between room temperature and high temperature region. The difference on thermal expansion betweenceramics and met...

  2. Verifying SeVeCom Using Set-based Abstraction

    DEFF Research Database (Denmark)

    Mödersheim, Sebastian Alexander; Modesti, Paolo

    We formally analyze the Secure Vehicle Communication system developed by the EU-project SeVeCom, using the AIF framework which is based on a novel set-abstraction technique. The model involves the hardware security modules (HSMs) of a number of cars, a certification authority, and the protocols e...... approaches in protocol abstraction, can handle databases that do not monotonically grow (and thus allow for revocation of keys). We report on two new attacks found and verify that under some reasonable assumptions, the system is secure in a black-box cryptography model....

  3. Verifying SeVeCom Using Set-based Abstraction

    DEFF Research Database (Denmark)

    Mödersheim, Sebastian Alexander; Modesti, Paolo

    2011-01-01

    We formally analyze the Secure Vehicle Communication system developed by the EU-project SeVeCom, using the AIF framework which is based on a novel set-abstraction technique. The model involves the hardware security modules (HSMs) of a number of cars, a certication authority, and the protocols exe...... approaches in protocol abstraction, can handle databases that do not monotonically grow (and thus allow for revocation of keys). We report on two new attacks found and verify that under some reasonable assumptions, the system is secure in a black-box cryptography model....

  4. Verifying SeVeCom Using Set-based Abstraction

    DEFF Research Database (Denmark)

    Mödersheim, Sebastian Alexander; Modesti, Paolo

    2011-01-01

    We formally analyze the Secure Vehicle Communication system developed by the EU-project SeVeCom, using the AIF framework which is based on a novel set-abstraction technique. The model involves the hardware security modules (HSMs) of a number of cars, a certication authority, and the protocols exe...... approaches in protocol abstraction, can handle databases that do not monotonically grow (and thus allow for revocation of keys). We report on two new attacks found and verify that under some reasonable assumptions, the system is secure in a black-box cryptography model....

  5. Arctic Boreal Vulnerability Experiment (ABoVE) Science Cloud

    Science.gov (United States)

    Duffy, D.; Schnase, J. L.; McInerney, M.; Webster, W. P.; Sinno, S.; Thompson, J. H.; Griffith, P. C.; Hoy, E.; Carroll, M.

    2014-12-01

    The effects of climate change are being revealed at alarming rates in the Arctic and Boreal regions of the planet. NASA's Terrestrial Ecology Program has launched a major field campaign to study these effects over the next 5 to 8 years. The Arctic Boreal Vulnerability Experiment (ABoVE) will challenge scientists to take measurements in the field, study remote observations, and even run models to better understand the impacts of a rapidly changing climate for areas of Alaska and western Canada. The NASA Center for Climate Simulation (NCCS) at the Goddard Space Flight Center (GSFC) has partnered with the Terrestrial Ecology Program to create a science cloud designed for this field campaign - the ABoVE Science Cloud. The cloud combines traditional high performance computing with emerging technologies to create an environment specifically designed for large-scale climate analytics. The ABoVE Science Cloud utilizes (1) virtualized high-speed InfiniBand networks, (2) a combination of high-performance file systems and object storage, and (3) virtual system environments tailored for data intensive, science applications. At the center of the architecture is a large object storage environment, much like a traditional high-performance file system, that supports data proximal processing using technologies like MapReduce on a Hadoop Distributed File System (HDFS). Surrounding the storage is a cloud of high performance compute resources with many processing cores and large memory coupled to the storage through an InfiniBand network. Virtual systems can be tailored to a specific scientist and provisioned on the compute resources with extremely high-speed network connectivity to the storage and to other virtual systems. In this talk, we will present the architectural components of the science cloud and examples of how it is being used to meet the needs of the ABoVE campaign. In our experience, the science cloud approach significantly lowers the barriers and risks to organizations

  6. Orman Yangınları ve Orman Amenajman Planları

    OpenAIRE

    BAYSAL, İsmail; BİLGİLİ, Ertuğrul; BAŞKENT, Emin Zeki

    2016-01-01

    Bu çalışma orman yangınlarının orman amenajmanı planlamalarına entegrasyonunu temel düzeyde ele almaktadır. Orman ekosistemleri sürekli bir değişim ve gelişim içindedir. Yangın, böcek ve fırtına gibi doğal afetler ile planlı ve plansız insan müdahaleleri, orman ekosistemlerinde meydana gelen bu değişimin ve gelişimin en önemli belirleyici unsurlarıdır. Nerede, ne zaman çıkacağı ve ne kadar bir alanda etkili olacağı bilinemeyen orman yangınları, planlamalardaki en önemli risk ve belirsizlik ka...

  7. Thermal Expansion in YbGaGe

    OpenAIRE

    Bobev, Svilen; Williams, Darrick J.; Thompson, J.D.; Sarrao, J L

    2004-01-01

    Thermal expansion and magnetic susceptibility measurements as a function of temperature are reported for YbGaGe. Despite the fact that this material has been claimed to show zero thermal expansion over a wide temperature range, we observe thermal expansion typical of metals and Pauli paramagnetic behavior, which perhaps indicates strong sample dependence in this system.

  8. Multiplier theorems for special Hermite expansions on

    Institute of Scientific and Technical Information of China (English)

    张震球; 郑维行

    2000-01-01

    The weak type (1,1) estimate for special Hermite expansions on Cn is proved by using the Calderon-Zygmund decomposition. Then the multiplier theorem in Lp(1 < p < ω ) is obtained. The special Hermite expansions in twisted Hardy space are also considered. As an application, the multipli-ers for a certain kind of Laguerre expansions are given in Lp space.

  9. An All-Orders Derivative Expansion

    OpenAIRE

    Dunne, Gerald(Department of Physics, University of Connecticut, Storrs, CT, 06269, U.S.A.)

    1996-01-01

    We evaluate the exact $QED_{2+1}$ effective action for fermions in the presence of a family of static but spatially inhomogeneous magnetic field profiles. This exact result yields an all-orders derivative expansion of the effective action, and indicates that the derivative expansion is an asymptotic, rather than a convergent, expansion.

  10. Quantum fields and "Big Rip" expansion singularities

    CERN Document Server

    Calderon, H; Calderon, Hector; Hiscock, William A.

    2005-01-01

    The effects of quantized conformally invariant massless fields on the evolution of cosmological models containing a ``Big Rip'' future expansion singularity are examined. Quantized scalar, spinor, and vector fields are found to strengthen the accelerating expansion of such models as they approach the expansion singularity.

  11. Volume Stability of Bitumen Bound Building Blocks

    Directory of Open Access Journals (Sweden)

    Thanaya I.N.A.

    2010-01-01

    Full Text Available This paper covers results of laboratory investigations on the volume stability of masonry units incorporating waste materials bound with bitumen (Bitublocks, due to moisture adsorption, thermal exposure and vacuum saturation. The materials used were steel slag, crushed glass, coal fly ash, and 50 pen bitumen. The samples were produced in hot mix method, compacted, then exposed to moist and temperature. It was found that moisture adsorption from the environment caused the Bitublock to expand. The samples with less intense curing regime experienced lower expansion and became stable faster, and vice versa. Under thermal condition (at 70°C, the samples with less intense curing regime underwent higher expansion, and vice versa. They were also highly reversible. Their volume stability was found unique under water exposure. The expansion on first vacuum saturation cycle was irreversible, then largely reversible on the following cycles.

  12. A simple reactivity feedback model accounting for radial core expansion effects in the liquid metal fast reactor

    Energy Technology Data Exchange (ETDEWEB)

    Kwon, Young Min; Lee, Yong Bum; Chang, Won Pyo; Haha, Do Hee [KAERI, Taejon (Korea, Republic of)

    2002-10-01

    The radial core expansion due to the structure temperature rise is one of major negative reactivity insertion mechanisms in metallic fueled reactor. Thermal expansion is a result of both the laws of nature and the particular core design and it causes negative reactivity feedback by the combination of increased core volume captures and increased core surface leakage. The simple radial core expansion reactivity feedback model developed for the SSC-K code was evaluated by the code-to-code comparison analysis. From the comparison results, it can be stated that the radial core expansion reactivity feedback model employed into the SSC-K code may be reasonably accurate in the UTOP analysis.

  13. Re-expansion pulmonary oedema: a novel emergency therapeutic option.

    Science.gov (United States)

    Sunderland, Nicholas; Maweni, Robert; Akunuri, Srikanth; Karnovitch, Elena

    2016-04-27

    Re-expansion pulmonary oedema (REPO) is a rare complication of pleural fluid thoracocentesis and has been associated with a high mortality rate. There is limited evidence to inform on its most effective management. We present two cases of large volume thoracocentesis resulting in acute respiratory decompensation that was treated by reintroducing the drained pleural fluid back into the pleural cavity. We also present a review of the literature specifically assessing the reported incidence rate of REPO after pleural fluid drainage. In both of our cases, symptoms and signs of respiratory instability were promptly reversed on reintroduction of the drained pleural fluid into the patient's pleural space-a therapy we have termed 'rapid pleural space re-expansion'. This was not associated with any short-term adverse outcomes. The occurrence of REPO is a rare event with most cohort studies reporting an incidence of between 0% and 1%.

  14. Speech Understanding Systems. Volume 5. Trip

    Science.gov (United States)

    1976-12-01

    modeling, parsing, pattern recognition, phonetic labeling, phonetic segmentation, phonological rules, phonology , pragmatic grammar, pragmatics...extraction, acoustic- phonetic analysis of the signal, phonological expansion of the lexicon, lexical matching and retrieval, syntactic analysis and...used by the assistant. Because acoustic, phonetic or phonological knowledge have been covered elsewhere (Volumes 1-3), we will be focusing on so-called

  15. Volume reduction through perturbative Wilson loops

    CERN Document Server

    Perez, Margarita Garcia; Okawa, Masanori

    2016-01-01

    We derive the perturbative expansion of Wilson loops to order g^4 in a SU(N) lattice gauge theory with twisted boundary conditions. Our expressions show that the thermodynamic limit is attained at infinite N for any number of lattice sites and allow to quantify the deviations from volume independence at finite large N as a function of the twist.

  16. Expansion of protein domain repeats.

    Directory of Open Access Journals (Sweden)

    Asa K Björklund

    2006-08-01

    Full Text Available Many proteins, especially in eukaryotes, contain tandem repeats of several domains from the same family. These repeats have a variety of binding properties and are involved in protein-protein interactions as well as binding to other ligands such as DNA and RNA. The rapid expansion of protein domain repeats is assumed to have evolved through internal tandem duplications. However, the exact mechanisms behind these tandem duplications are not well-understood. Here, we have studied the evolution, function, protein structure, gene structure, and phylogenetic distribution of domain repeats. For this purpose we have assigned Pfam-A domain families to 24 proteomes with more sensitive domain assignments in the repeat regions. These assignments confirmed previous findings that eukaryotes, and in particular vertebrates, contain a much higher fraction of proteins with repeats compared with prokaryotes. The internal sequence similarity in each protein revealed that the domain repeats are often expanded through duplications of several domains at a time, while the duplication of one domain is less common. Many of the repeats appear to have been duplicated in the middle of the repeat region. This is in strong contrast to the evolution of other proteins that mainly works through additions of single domains at either terminus. Further, we found that some domain families show distinct duplication patterns, e.g., nebulin domains have mainly been expanded with a unit of seven domains at a time, while duplications of other domain families involve varying numbers of domains. Finally, no common mechanism for the expansion of all repeats could be detected. We found that the duplication patterns show no dependence on the size of the domains. Further, repeat expansion in some families can possibly be explained by shuffling of exons. However, exon shuffling could not have created all repeats.

  17. Gravitational entropy of cosmic expansion

    CERN Document Server

    Sussman, Roberto A

    2014-01-01

    We apply a recent proposal to define "gravitational entropy" to the expansion of cosmic voids within the framework of non-perturbative General Relativity. By considering CDM void configurations compatible with basic observational constraints, we show that this entropy grows from post-inflationary conditions towards a final asymptotic value in a late time fully non-linear regime described by the Lemaitre-Tolman-Bondi (LTB) dust models. A qualitatively analogous behavior occurs if we assume a positive cosmological constant consistent with a $\\Lambda$-CDM background model. However, the $\\Lambda$ term introduces a significant suppression of entropy growth with the terminal equilibrium value reached at a much faster rate.

  18. Contribution of thermal expansion and

    Directory of Open Access Journals (Sweden)

    O.I.Pursky

    2007-01-01

    Full Text Available A theoretical model is developed to describe the experimental results obtained for the isobaric thermal conductivity of rare gas solids (RGS. The isobaric thermal conductivity of RGS has been analysed within Debye approximation with regard to the effect of thermal expansion. The suggested model takes into consideration the fact that thermal conductivity is determined by U-processes while above the phonon mobility edge it is determined by "diffusive" modes migrating randomly from site to site. The mobility edge ω0 is determined from the condition that the phonon mean-free path restricted by the U-processes cannot be smaller than half of the phonon wavelength.

  19. Cosmic Growth and Expansion Conjoined

    CERN Document Server

    Linder, Eric V

    2016-01-01

    Cosmological measurements of both the expansion history and growth history have matured, and the two together provide an important test of general relativity. We consider their joint evolutionary track, showing that this has advantages in distinguishing cosmologies relative to considering them individually or at isolated redshifts. In particular, the joint comparison relaxes the shape degeneracy that makes $f\\sigma_8(z)$ curves difficult to separate from the overall growth amplitude. The conjoined method further helps visualization of which combinations of redshift ranges provide the clearest discrimination. We examine standard dark energy cosmologies, modified gravity, and "stuttering" growth, each showing distinct signatures.

  20. Üniversite Psikolojik Danışma ve Rehberlik Merkezleri’nin Rol ve İşlevleri: Gelişmeler ve Sınırlılıklar

    Directory of Open Access Journals (Sweden)

    Cem Ali Gizir

    2010-11-01

    Full Text Available Son yıllardaki hızlı sosyal, kültürel, ekonomik ve politik değişimlere bağlı olaraküniversite Psikolojik Danışma ve Rehberlik (PDR merkezlerinin rol ve işlevlerinde deönemli değişiklikler meydana gelmektedir. Dolayısıyla, geçmişten günümüze akademik vekariyer gelişimi konusundaki geleneksel temel rollerinin yanı sıra son yıllardaki üniversiteöğrencilerinin kişisel ve sosyal problemlerindeki değişiklikler ve artışlara bağlı olaraküniversite PDR merkezlerinin rol ve işlevlerinin yeniden değerlendirilmesi önem arzetmektedir. Bu bilgiler ışığında, özellikle Türkiye’deki üniversite PDR merkezlerinin rol veişlevlerinin etkinleştirilmesinde yarar sağlayacağı düşünülen bu derleme çalışmasınınamacı, tarihsel gelişim süreciyle birlikte ortaya çıkan ortak temalar doğrultusunda,günümüz üniversite PDR merkezlerinin rol ve işlevlerine yönelik son gelişmeler üzerine birdeğerlendirme yapmak ve Uluslararası Psikolojik Danışma Hizmetleri Derneğinin (IACSakreditasyon standartları temelinde varolan sınırlılıklar ile çözüm önerilerini ortaya koymaktır.

  1. Digital expansions with negative real bases

    CERN Document Server

    Steiner, Wolfgang

    2011-01-01

    Similarly to Parry's characterization of $\\beta$-expansions of real numbers in real bases $\\beta > 1$, Ito and Sadahiro characterized digital expansions in negative bases, by the expansions of the endpoints of the fundamental interval. Parry also described the possible expansions of 1 in base $\\beta > 1$. In the same vein, we characterize the sequences that occur as $(-\\beta)$-expansion of $\\frac{-\\beta}{\\beta+1}$ for some $\\beta > 1$. These sequences also describe the itineraries of 1 by linear mod one transformations with negative slope.

  2. Université de Genève

    CERN Multimedia

    2008-01-01

    Ecole de physique - Département de physique nucléaire et corspusculaire 24, quai Ernest-Ansermet 1211 GENÈVE 4 Tél: (022) 379 62 73 - Fax: (022) 379 69 92 Lundi 1er décembre 2008 PARTICLE PHYSICS SEMINAR at 17.00 hrs – Stückelberg Auditorium Superconducting Interfaces between Insulating Oxide Prof. Jean-Marc TRISCONE / Université de Genève At interfaces between complex oxides, electronic systems with unusual properties can be generated. A striking example is the interface between LaAlO3 and SrTiO3, two good insulating perovskite oxides, which was found in 2004 to be conducting with a high mobility. We recently discovered that the ground state of this system is a superconducting condensate, with a critical temperature of about 200 mK. The characteristics observed for the superconducting transitions are consistent with a two-dimensional superconducting sheet as thin as a few nanometers. Recent field effect experiments revealed the sensitivity of the normal and superconducting states to the carrier d...

  3. Almanya'da Türk Argosu ve Rap

    OpenAIRE

    GENÇ, Safiye

    2015-01-01

    Almanya’daki göçmen gençlerin kullanımında yaygın olan Türk Argosunun ortaya çıkışı ve bu gençler için neyi temsil ettiği bu çalışmanın ana konusudur. Türk Argosunun en çok kullanıldığı alan ise Rap müziğidir. Rap müziği 80’li yılların ortalarından itibaren Almanya’da yaşayan göçmen gençlerin kendilerini ifade edebilecekleri bir müzik türü haline gelmiştir. Türk Argosu ve Rap müziği bağlantısı bu kapsamda ele alınacaktır.Anahtar Sözcükler: Türk argosu, Türk göçmenler, Hiphop kültürü, Rap müzi...

  4. Université de Genève

    CERN Multimedia

    2008-01-01

    Ecole de physique - Département de physique nucléaire et corspusculaire 24, quai Ernest-Ansermet - 1211 GENÈVE 4 Tél: (022) 379 62 73 - Fax: (022) 379 69 92 Lundi 1er décembre 2008 PARTICLE PHYSICS SEMINAR at 17.00 hrs – Stückelberg Auditorium Superconducting Interfaces between Insulating Oxide Prof. Jean-Marc TRISCONE / Université de Genève At interfaces between complex oxides, electronic systems with unusual properties can be generated. A striking example is the interface between LaAlO3 and SrTiO3, two good insulating perovskite oxides, which was found in 2004 to be conducting with a high mobility. We recently discovered that the ground state of this system is a superconducting condensate, with a critical temperature of about 200 mK. The characteristics observed for the superconducting transitions are consistent with a two-dimensional superconducting sheet as thin as a few nanometers. Recent field effect experiments revealed the sensitivity of the normal and superconducting states to the carrier ...

  5. Uncertainty evaluation of the IMGC-CNR static expansion system

    Science.gov (United States)

    Bergoglio, M.; Calcatelli, A.

    2004-08-01

    A primary system based on the so-called static expansion of gases has been made available at IMGC-CNR for gauge calibration in the range 0.1 Pa to 1000 Pa. As is known, in such systems the generated pressure is calculated by application of the ideal gas law and is a function of the inlet pressure, the temperatures of the various volumes and their ratios. The uncertainty evaluation of the pressure measured with such system is the main subject of this paper. At present, the system is operated with three volumes (ap0.01 litre, ap0.5 litre and ap50 litre) and two expansion ratios (R4 cong 4761 and R3 cong 95) determined by application of the multiple expansion method through pressure measurements performed with the best transfer gauges available at IMGC-CNR. The characteristics of such transfer gauges are discussed with respect to two different conditions of use: that is, for determination of the expansion ratio, Rj, and for measurements of the inlet pressure. The combined expanded uncertainty of the generated pressure (pxi) is then given by \\[ \\begin{equation*}U(p_{\\it xi})/Pa=1.0\\times 10^{-4}+1.7\\times 10^{-3}p_{\\it xi}/Pa\\ in\\ the\\ pressure\\ range\\ 0.1\\,Pa\\ to\\ 10\\,Pa\\end{equation*} \\] and \\[ \\begin{equation*}U(p_{\\it xi})/Pa=1.7\\times 10^{-2}+8.2\\times 10^{-4} p_{\\it xi}/Pa\\ in\\ the\\ range\\ 10\\,Pa\\ to\\ 1000\\,Pa.\\end{equation*} \\] Considerations on participation in comparisons are also presented.

  6. Unravelling the fundamentals of thermal and chemical expansion of BaCeO3 from first principles phonon calculations.

    Science.gov (United States)

    Løken, Andreas; Haugsrud, Reidar; Bjørheim, Tor S

    2016-11-16

    Differentiating chemical and thermal expansion is virtually impossible to achieve experimentally. While thermal expansion stems from a softening of the phonon spectra, chemical expansion depends on the chemical composition of the material. In the present contribution, we, for the first time, completely decouple thermal and chemical expansion through first principles phonon calculations on BaCeO3, providing new fundamental insights to lattice expansion. We assess the influence of defects on thermal expansion, and how this in turn affects the interpretation of chemical expansion and defect thermodynamics. The calculations reveal that the linear thermal expansion coefficient is lowered by the introduction of oxygen vacancies being 10.6 × 10(-6) K(-1) at 300 K relative to 12.2 × 10(-6) K(-1) for both the protonated and defect-free bulk lattice. We further demonstrate that the chemical expansion coefficient upon hydration varies with temperature, ranging from 0.070 to 0.115 per mole oxygen vacancy. Ultimately, we find that, due to differences in the thermal expansion coefficients under dry and wet conditions, the chemical expansion coefficients determined experimentally are grossly underestimated - around 55% lower in the case of 10 mol% acceptor doped BaCeO3. Lastly, we evaluate the effect of these volume changes on the vibrational thermodynamics.

  7. Marrow Adipose Tissue Expansion Coincides with Insulin Resistance in MAGP1-Deficient Mice.

    Science.gov (United States)

    Walji, Tezin A; Turecamo, Sarah E; Sanchez, Alejandro Coca; Anthony, Bryan A; Abou-Ezzi, Grazia; Scheller, Erica L; Link, Daniel C; Mecham, Robert P; Craft, Clarissa S

    2016-01-01

    Marrow adipose tissue (MAT) is an endocrine organ with the potential to influence skeletal remodeling and hematopoiesis. Pathologic MAT expansion has been studied in the context of severe metabolic challenge, including caloric restriction, high fat diet feeding, and leptin deficiency. However, the rapid change in peripheral fat and glucose metabolism associated with these models impedes our ability to examine which metabolic parameters precede or coincide with MAT expansion. Microfibril-associated glycoprotein-1 (MAGP1) is a matricellular protein that influences cellular processes by tethering signaling molecules to extracellular matrix structures. MAGP1-deficient (Mfap2 (-/-)) mice display a progressive excess adiposity phenotype, which precedes insulin resistance and occurs without changes in caloric intake or ambulation. Mfap2 (-/-) mice were, therefore, used as a model to associate parameters of metabolic disease, bone remodeling, and hematopoiesis with MAT expansion. Marrow adiposity was normal in Mfap2 (-/-) mice until 6 months of age; however, by 10 months, marrow fat volume had increased fivefold relative to wild-type control at the same age. Increased gonadal fat pad mass and hyperglycemia were detectable in Mfap2 (-/-) mice by 2 months, but peaked by 6 months. The development of insulin resistance coincided with MAT expansion. Longitudinal characterization of bone mass demonstrated a disconnection in MAT volume and bone volume. Specifically, Mfap2 (-/-) mice had reduced trabecular bone volume by 2 months, but this phenotype did not progress with age or MAT expansion. Interestingly, MAT expansion in the 10-month-old Mfap2 (-/-) mice was associated with modest alterations in basal hematopoiesis, including a shift from granulopoiesis to B lymphopoiesis. Together, these findings indicate MAT expansion is coincident with insulin resistance, but not excess peripheral adiposity or hyperglycemia in Mfap2 (-/-) mice; and substantial MAT accumulation does

  8. Medicaid Expansion In 2014 Did Not Increase Emergency Department Use But Did Change Insurance Payer Mix.

    Science.gov (United States)

    Pines, Jesse M; Zocchi, Mark; Moghtaderi, Ali; Black, Bernard; Farmer, Steven A; Hufstetler, Greg; Klauer, Kevin; Pilgrim, Randy

    2016-08-01

    In 2014 twenty-eight states and the District of Columbia had expanded Medicaid eligibility while federal and state-based Marketplaces in every state made subsidized private health insurance available to qualified individuals. As a result, about seventeen million previously uninsured Americans gained health insurance in 2014. Many policy makers had predicted that Medicaid expansion would lead to greatly increased use of hospital emergency departments (EDs). We examined the effect of insurance expansion on ED use in 478 hospitals in 36 states during the first year of expansion (2014). In difference-in-differences analyses, Medicaid expansion increased Medicaid-paid ED visits in those states by 27.1 percent, decreased uninsured visits by 31.4 percent, and decreased privately insured visits by 6.7 percent during the first year of expansion compared to nonexpansion states. Overall, however, total ED visits grew by less than 3 percent in 2014 compared to 2012-13, with no significant difference between expansion and nonexpansion states. Thus, the expansion of Medicaid coverage strongly affected payer mix but did not significantly affect overall ED use, even though more people gained insurance coverage in expansion states than in nonexpansion states. This suggests that expanding Medicaid did not significantly increase or decrease overall ED visit volume.

  9. Primordial vorticity and gradient expansion

    Science.gov (United States)

    Giovannini, Massimo; Rezaei, Zahra

    2012-02-01

    The evolution equations of the vorticities of the electrons, ions and photons in a pre-decoupling plasma are derived, in a fully inhomogeneous geometry, by combining the general relativistic gradient expansion and the drift approximation within the Adler-Misner-Deser decomposition. The vorticity transfer between the different species is discussed in this novel framework and a set of general conservation laws, connecting the vorticities of the three-component plasma with the magnetic field intensity, is derived. After demonstrating that a source of large-scale vorticity resides in the spatial gradients of the geometry and of the electromagnetic sources, the total vorticity is estimated to lowest order in the spatial gradients and by enforcing the validity of the momentum constraint. By acknowledging the current bounds on the tensor to scalar ratio in the (minimal) tensor extension of the ΛCDM paradigm, the maximal comoving magnetic field induced by the total vorticity turns out to be, at most, of the order of 10-37 G over the typical comoving scales ranging between 1 and 10 Mpc. While the obtained results seem to be irrelevant for seeding a reasonable galactic dynamo action, they demonstrate how the proposed fully inhomogeneous treatment can be used for the systematic scrutiny of pre-decoupling plasmas beyond the conventional perturbative expansions.

  10. Imagination as expansion of experience.

    Science.gov (United States)

    Zittoun, Tania; Cerchia, Frédéric

    2013-09-01

    This paper proposes a developmental view on imagination: from this perspective, imagination can be seen as triggered by some disrupting event, which generates a disjunction from the person's unfolding experience of the "real" world, and as unfolding as a loop, which eventually comes back to the actual experience. Examining recent and classical theorization of imagination in psychology, the paper opposes a deficitary view of imagination to an expansive notion of imagination. The paper explores Piaget, Vygotsky, Harris and Pelaprat & Cole consider: 1) What does provoke a "rupture" or disjunction? 2) What are the psychological processes involved in the imaginary loop? 3) What nourishes such processes? 4) What are the consequences of such imaginary loop, or what does it enable doing? The paper proposes to adopt an expansive view of imagination, as Vygotsky proposed-a perspective that has been under-explored empirically since his seminal work. To stimulate such sociocultural psychology of imagination, two empirical examples are provided, one showing how children make sense of metaphor in an experimental setting, the other showing a young person using a novel met at school as symbolic resource.

  11. Evolutionary expansion of the Monogenea.

    Science.gov (United States)

    Kearn, G C

    1994-12-01

    The evolutionary expansion of the monogeneans has taken place in parallel with the diversification of the fish-like vertebrates. In this article the main trends in monogenean evolution are traced from a hypothetical skin-parasitic ancestor on early vertebrates. Special consideration is given to the following topics: early divergence between skin feeders and blood feeders; diversification and specialization of the haptor for attachment to skin; transfer from host to host, viviparity and the success of the gyrodactylids; predation on skin parasites and camouflage; colonization of the buccal and branchial cavities; diversification and specialization of the haptor for attachment to the gills; phoresy in gill parasites; the development of endoparasitism and the origin of the cestodes; the success of dactylogyroidean gill parasites; the uniqueness of the polyopisthocotyleans; ovoviviparity and the colonization of the tetrapods. Host specificity has been the guiding force of coevolution between monogeneans and their vertebrate hosts, but the establishment of monogeneans on unrelated hosts sharing the same environment (host-switching) may have been underestimated. Host-switching has provided significant opportunities for evolutionary change of direction and is probably responsible for the establishment of monogeneans on cephalopod molluscs, on the hippopotamus and possibly on chelonians. There are indications that host-switching may be more common in monogeneans that spread by direct transfer of adults/juveniles from host to host. A limitation on the further expansion of monogeneans is the need for water for the dispersal of the infective larva (oncomiracidium).

  12. Fast algorithms for Quadrature by Expansion I: Globally valid expansions

    Science.gov (United States)

    Rachh, Manas; Klöckner, Andreas; O'Neil, Michael

    2017-09-01

    The use of integral equation methods for the efficient numerical solution of PDE boundary value problems requires two main tools: quadrature rules for the evaluation of layer potential integral operators with singular kernels, and fast algorithms for solving the resulting dense linear systems. Classically, these tools were developed separately. In this work, we present a unified numerical scheme based on coupling Quadrature by Expansion, a recent quadrature method, to a customized Fast Multipole Method (FMM) for the Helmholtz equation in two dimensions. The method allows the evaluation of layer potentials in linear-time complexity, anywhere in space, with a uniform, user-chosen level of accuracy as a black-box computational method. Providing this capability requires geometric and algorithmic considerations beyond the needs of standard FMMs as well as careful consideration of the accuracy of multipole translations. We illustrate the speed and accuracy of our method with various numerical examples.

  13. Renormalized Volume

    Science.gov (United States)

    Gover, A. Rod; Waldron, Andrew

    2017-09-01

    We develop a universal distributional calculus for regulated volumes of metrics that are suitably singular along hypersurfaces. When the hypersurface is a conformal infinity we give simple integrated distribution expressions for the divergences and anomaly of the regulated volume functional valid for any choice of regulator. For closed hypersurfaces or conformally compact geometries, methods from a previously developed boundary calculus for conformally compact manifolds can be applied to give explicit holographic formulæ for the divergences and anomaly expressed as hypersurface integrals over local quantities (the method also extends to non-closed hypersurfaces). The resulting anomaly does not depend on any particular choice of regulator, while the regulator dependence of the divergences is precisely captured by these formulæ. Conformal hypersurface invariants can be studied by demanding that the singular metric obey, smoothly and formally to a suitable order, a Yamabe type problem with boundary data along the conformal infinity. We prove that the volume anomaly for these singular Yamabe solutions is a conformally invariant integral of a local Q-curvature that generalizes the Branson Q-curvature by including data of the embedding. In each dimension this canonically defines a higher dimensional generalization of the Willmore energy/rigid string action. Recently, Graham proved that the first variation of the volume anomaly recovers the density obstructing smooth solutions to this singular Yamabe problem; we give a new proof of this result employing our boundary calculus. Physical applications of our results include studies of quantum corrections to entanglement entropies.

  14. Evaluation of the VE1 Antibody in Thyroid Cytology Using Papillary Thyroid Carcinoma Specimens

    Directory of Open Access Journals (Sweden)

    Yon Hee Kim

    2016-01-01

    Full Text Available Background: Recently, VE1, a monoclonal antibody against the BRAFV600E mutant protein, has been investigated in terms of its detection of the BRAFV600E mutation. Although VE1 immunostaining and molecular methods used to assess papillary thyroid carcinoma in surgical specimens are in good agreement, evaluation of VE1 in thyroid cytology samples is rarely performed, and its diagnostic value in cytology has not been well established. In present study, we explored VE1 immunoexpression in cytology samples from ex vivo papillary thyroid carcinoma specimens in order to minimize limitations of low cellularity and sampling/targeting errors originated from thyroid fineneedle aspiration and compared our results with those obtained using the corresponding papillary thyroid carcinoma tissues. Methods: The VE1 antibody was evaluated in 21 cases of thyroid cytology obtained directly from ex vivo thyroid specimens. VE1 immunostaining was performed using liquid-based cytology, and the results were compared with those obtained using the corresponding tissues. Results: Of 21 cases, 19 classic papillary thyroid carcinomas had BRAFV600E mutations, whereas two follicular variants expressed wild-type BRAF. VE1 immunoexpression varied according to specimen type. In detection of the BRAFV600E mutation, VE1 immunostaining of the surgical specimen exhibited 100% sensitivity and 100% specificity, whereas VE1 immunostaining of the cytology specimen exhibited only 94.7% sensitivity and 0% specificity. Conclusions: Our data suggest that VE1 immunostaining of a cytology specimen is less specific than that of a surgical specimen for detection of the BRAFV600E mutation, and that VE1 immunostaining of a cytology specimen should be further evaluated and optimized for clinical use.

  15. Effect of IL-7 therapy on naïve and memory T cell homeostasis in aged rhesus macaques

    Science.gov (United States)

    Okoye, Afam A.; Rohankhedkar, Mukta; Konfe, Audrie L.; Abana, Chike O.; Reyes, Matthew D.; Clock, Joseph A.; Duell, Derick M.; Sylwester, Andrew W.; Sammader, Partha; Legasse, Alfred W.; Park, Byung S.; Axthelm, Michael K.; Nikolich-Žugich, Janko; Picker, Louis J.

    2015-01-01

    Aging is associated with gradual deterioration of adaptive immune function, a hallmark of which is the profound loss of naïve T cells (TN) associated with decline in thymic output and export of new cells into the peripheral T cell pool. Since the lymphotropic cytokine IL-7 plays crucial roles in both development of TN in the thymus and TN homeostasis in the periphery, we sought to determine the extent to which therapeutic administration of IL-7 could reverse TN deficiency in aging rhesus macaques (RM), either by enhancement of the demonstrably reduced thymopoiesis or by peripheral TN expansion. Our results indicate that treatment of both adult (8–15 years) and old (>20 years) RM with recombinant simian IL-7 (rsIL-7) results in only transient increases in peripheral CD4+ and CD8+ TN numbers with no long-term benefit, even with repeated therapy. This transient effect was due to peripheral TN expansion and not enhanced thymic function, and appeared to be limited by induction of IL-7 non-responsiveness. However, rsIL-7 therapy had a more promising effect on the central memory T cell (TCM) population (both CD4+ and CD8+) in adult and old RM, doubling the numbers of these cells in circulation and maintaining this larger population long-term. IL-7 therapy didn't reduce TCR diversity of the memory T cell compartment, suggesting that rsIL-7-induced expansion was symmetrical. Thus, although rsIL-7 failed to counter age-associated TN loss, the ability of this therapy to expand clonotypically diverse CD4+ and CD8+ TCM populations might potentially improve adaptive immune responsiveness in the elderly. PMID:26416281

  16. SOYA VE ÜRÜNLERİNDE FENOLİK BİLEŞİKLER VE BESLENMEYİ KISITLAYICI FAKTÖRLER

    OpenAIRE

    2001-01-01

    Protein bakımından zengin bir ürün olan soya fasulyesinin kullanım alanları hızla artmaktadır. Soya ve soya proteini ürünlerinin teknolojik açıdan çok iyi özellikleri olmasına rağmen, bazı istenmeyen renk ve koku karakteristikleri ile yapılarında bulunan beslenmeyi kısıtlayıcı faktörler kullanımını sınırlandırmaktadır. Bu derlemede, soya fasulyesi ve ürünlerindeki fenolik bileşikler ile beslenmeyi kısıtlayıcı faktörler ve bunların giderilmesi konusu üzerinde durulmuştur....

  17. A new isotropic cell for studying the thermo-mechanical behavior of unsaturated expansive clays

    CERN Document Server

    Tang, Anh-Minh; Barnel, Nathalie

    2007-01-01

    This paper presents a new suction-temperature controlled isotropic cell that can be used to study the thermo-mechanical behavior of unsaturated expansive clays. The vapor equilibrium technique is used to control the soil suction; the temperature of the cell is controlled using a thermostat bath. The isotropic pressure is applied using a volume/pressure controller that is also used to monitor the volume change of soil specimen. Preliminary experimental results showed good performance of the cell.

  18. FIJI Macro 3D ART VeSElecT: 3D Automated Reconstruction Tool for Vesicle Structures of Electron Tomograms.

    Science.gov (United States)

    Kaltdorf, Kristin Verena; Schulze, Katja; Helmprobst, Frederik; Kollmannsberger, Philip; Dandekar, Thomas; Stigloher, Christian

    2017-01-01

    Automatic image reconstruction is critical to cope with steadily increasing data from advanced microscopy. We describe here the Fiji macro 3D ART VeSElecT which we developed to study synaptic vesicles in electron tomograms. We apply this tool to quantify vesicle properties (i) in embryonic Danio rerio 4 and 8 days past fertilization (dpf) and (ii) to compare Caenorhabditis elegans N2 neuromuscular junctions (NMJ) wild-type and its septin mutant (unc-59(e261)). We demonstrate development-specific and mutant-specific changes in synaptic vesicle pools in both models. We confirm the functionality of our macro by applying our 3D ART VeSElecT on zebrafish NMJ showing smaller vesicles in 8 dpf embryos then 4 dpf, which was validated by manual reconstruction of the vesicle pool. Furthermore, we analyze the impact of C. elegans septin mutant unc-59(e261) on vesicle pool formation and vesicle size. Automated vesicle registration and characterization was implemented in Fiji as two macros (registration and measurement). This flexible arrangement allows in particular reducing false positives by an optional manual revision step. Preprocessing and contrast enhancement work on image-stacks of 1nm/pixel in x and y direction. Semi-automated cell selection was integrated. 3D ART VeSElecT removes interfering components, detects vesicles by 3D segmentation and calculates vesicle volume and diameter (spherical approximation, inner/outer diameter). Results are collected in color using the RoiManager plugin including the possibility of manual removal of non-matching confounder vesicles. Detailed evaluation considered performance (detected vesicles) and specificity (true vesicles) as well as precision and recall. We furthermore show gain in segmentation and morphological filtering compared to learning based methods and a large time gain compared to manual segmentation. 3D ART VeSElecT shows small error rates and its speed gain can be up to 68 times faster in comparison to manual annotation

  19. 被动抬腿试验评估感染性休克患者容量反应性的临床研究%Clinical Study of Passive Leg Raising Trial to Predict Volume Responsiveness in Septic Shock

    Institute of Scientific and Technical Information of China (English)

    郭志利; 王勇强

    2015-01-01

    目的:评价被动抬腿试验(PLR)预测感染性休克患者的容量反应性。方法:采用前瞻性、观察性队列研究设计方法,选择34例感染性休克患者,先后进行 PLR 和容量负荷试验(VE),分别在 PLR 前(基线)、PLR 期间和 VE 后用超声心动图(TTE)测量记录每搏量(SV)并记录血流动力学变化。根据对容量负荷试验的反应(以 VE 后 SV 增加≥15%定义为有容量反应性)将患者分为有反应组和无反应组。用受试者工作特征曲线(ROC 曲线)评价 PLR 预测感染性休克患者的容量反应性。结果:34例患者中有反应组16例,无反应组18例。 VE 和 PLR 引起的ΔSV 存在显著直线相关性,Person 相关系数为0.630,P=0.000;PLR 诱导的ΔSV 预测感染性休克患者的容量反应性 ROC 曲线下面积(AUC)为0.866±0.064[95%可信区间(CI)为0.741~0.992,P=0.000],在 PLR 期间ΔSV 为11.84%时诊断容量反应性的敏感度为93.8%,特异度为72.2%。结论:PLR 在预测感染性休克患者的容量反应性具有良好的价值。%Objective :To investigate the ability of passive leg raising (PLR) trial predicting volume responsiveness in septic shock .Methods :The prospective and observational cohort study was performed in 34 septic shock patients .PLR and volume expansion(VE) has been carried out successively .Respectively ,in front of the PLR (baseline) ,during the period of PLR and after VE using echocardiography measure stroke volume (SV) and hemodynamic changes in the re‐cord .According to the responsiveness of volume expansion (Responders were defined by the appearance of an increase in SV ≥ 15% after VE) ,patients were divided into responders and non‐responders .Using the receiver operating char‐acteristic curve (ROC curve) analysis PLR assessment of volume responsiveness in patients with septic shock .Results :A total of 34 patients were

  20. SCHIFF BAZI VE MAKROSİKLİK HALKA İÇEREN, POLİMER-METAL KOMPLEKSLERİNİN HAZIRLANMASI VE YAPILARININ AYDINLATILMASI

    Directory of Open Access Journals (Sweden)

    SEDA TIĞLI

    2005-01-01

    Full Text Available Bu çalışmada, polimerik-ınetal kompleksleri hazırlamaya elverişli bifonksiyonel ligandlar sentezlendi.Bu ligandların Ni(In Co(D polimerik kompleksleri hazırlandı. Ligand ve polimerik kompleksierin yapıları FT-IR, 1H-NMR, 13C-NMR ve Kütle spektroskopisi gibi spekstroskopik yöntemlerle avdtnlatıldı.

  1. On the Equisummability of Hermite and Fourier Expansions

    Indian Academy of Sciences (India)

    E K Narayanan; S Thangavelu

    2001-02-01

    We prove an equisummability result for the Fourier expansions and Hermite expansions as well as special Hermite expansions. We also prove the uniform boundedness of the Bochner-Riesz means associated to the Hermite expansions for polyradial functions.

  2. Shrub expansion in SW Greenland

    DEFF Research Database (Denmark)

    Jørgensen, Rasmus Halfdan

    to increasing shrub cover. Despite this, there is only limited experimental evidence that growth of the species responds to warming. Plant populations in fragmented and isolated locations could face problems adapting to a warming climate due to limited genetic variation and restricted migration from southern...... of firewood collection. A delayed reaction to the ending of the little ice age cannot be excluded, but seems rather unlikely considering other studies from Greenland. Effects of global warming in SW Greenland must be studied over even longer time periods than the 120 years of the current study. To answer......Arctic regions have experienced higher temperatures in recent decades, and the warming trend is projected to continue in the coming years. Arctic ecosystems are considered to be particularly vulnerable to climate change. Expansion of shrubs has been observed widely in tundra areas across the Arctic...

  3. Bilinear Expansion For Redistribution Functions

    Science.gov (United States)

    Harutyunian, Haik; Alecian, Georges; Khachatryan, Knarik; Vardanyan, Ani

    2016-11-01

    We suggest here a method for construction of a bilinear expansion for an angle-averaged redistribution function. This function describes the elementary act of a photon scattering by a model two-level atom with the upper level broadened due to radiation damping. An eigenvalue and eigenvector determination problem is formulated and the relevant matrices are found analytically. Numerical procedures for their computations are elaborated as well. A simple method for the numerical calculations accuracy evaluation is suggested. It is shown that a family of redistribution functions describing the light scattering process within the spectral line frequencies can be constructed if the eigenvalue problem for the considered function is solved. It becomes possible if the eigenvalues and eigenvectors with the appropriate basic functions are used. The Voigt function and its derivatives used as basic functions are studied in detail as well.

  4. Accelerating Expansion of the Universe

    CERN Document Server

    Chakraborty, Writambhara

    2011-01-01

    This thesis concentrates on the accelerated expansion of the Universe recently explored by measurements of redshift and luminosity-distance relations of type Ia Supernovae. We have considered a model of the universe filled with modified Chaplygin gas and barotropic fluid. The role of dynamical cosmological constant has been explored with Modified Chaplygin Gas as the background fluid. Various phenomenological models for \\Lambda have been studied in presence of the gravitational constant G to be constant or time dependent. A new form of the well known Chaplygin gas model has been presented by introducing inhomogeneity in the EOS. This model explains w=-1 crossing. An interaction of this model with the scalar field has also been investigated through a phenomenological coupling function. Tachyonic field has been depicted as dark energy model to represent the present acceleration of the Universe. A mixture of the tachyonic fluid has been considered with Generalized Chaplygin Gas to show the role of the later as a...

  5. Asymptotic expansions in nonlinear rotordynamics

    Science.gov (United States)

    Day, William B.

    1987-01-01

    This paper is an examination of special nonlinearities of the Jeffcott equations in rotordynamics. The immediate application of this analysis is directed toward understanding the excessive vibrations recorded in the LOX pump of the SSME during hot-firing ground testing. Deadband, side force, and rubbing are three possible sources of inducing nonlinearity in the Jeffcott equations. The present analysis initially reduces these problems to the same mathematical description. A special frequency, named the nonlinear natural frequency, is defined and used to develop the solutions of the nonlinear Jeffcott equations as singular asymptotic expansions. This nonlinear natural frequency, which is the ratio of the cross-stiffness and the damping, plays a major role in determining response frequencies.

  6. Colossal negative thermal expansion in BiNiO3 induced by intermetallic charge transfer.

    Science.gov (United States)

    Azuma, Masaki; Chen, Wei-tin; Seki, Hayato; Czapski, Michal; Olga, Smirnova; Oka, Kengo; Mizumaki, Masaichiro; Watanuki, Tetsu; Ishimatsu, Naoki; Kawamura, Naomi; Ishiwata, Shintaro; Tucker, Matthew G; Shimakawa, Yuichi; Attfield, J Paul

    2011-06-14

    The unusual property of negative thermal expansion is of fundamental interest and may be used to fabricate composites with zero or other controlled thermal expansion values. Here we report that colossal negative thermal expansion (defined as linear expansion transfer transitions. BiNiO(3) shows a 2.6% volume reduction under pressure due to a Bi/Ni charge transfer that is shifted to ambient pressure through lanthanum substitution for Bi. Changing proportions of coexisting low- and high-temperature phases leads to smooth volume shrinkage on heating. The crystallographic linear expansion coefficient for Bi(0.95)La(0.05)NiO(3) is -137×10(-6) K(-1) and a value of -82×10(-6) K(-1) is observed between 320 and 380 K from a dilatometric measurement on a ceramic pellet. Colossal negative thermal expansion materials operating at ambient conditions may also be accessible through metal-insulator transitions driven by other phenomena such as ferroelectric orders.

  7. Colossal negative thermal expansion in BiNiO3 induced by intermetallic charge transfer

    Science.gov (United States)

    Azuma, Masaki; Chen, Wei-tin; Seki, Hayato; Czapski, Michal; Olga, Smirnova; Oka, Kengo; Mizumaki, Masaichiro; Watanuki, Tetsu; Ishimatsu, Naoki; Kawamura, Naomi; Ishiwata, Shintaro; Tucker, Matthew G.; Shimakawa, Yuichi; Attfield, J. Paul

    2011-01-01

    The unusual property of negative thermal expansion is of fundamental interest and may be used to fabricate composites with zero or other controlled thermal expansion values. Here we report that colossal negative thermal expansion (defined as linear expansion <−10−4 K−1 over a temperature range ~100 K) is accessible in perovskite oxides showing charge-transfer transitions. BiNiO3 shows a 2.6% volume reduction under pressure due to a Bi/Ni charge transfer that is shifted to ambient pressure through lanthanum substitution for Bi. Changing proportions of coexisting low- and high-temperature phases leads to smooth volume shrinkage on heating. The crystallographic linear expansion coefficient for Bi0.95La0.05NiO3 is −137×10−6 K−1 and a value of −82×10−6 K−1 is observed between 320 and 380 K from a dilatometric measurement on a ceramic pellet. Colossal negative thermal expansion materials operating at ambient conditions may also be accessible through metal-insulator transitions driven by other phenomena such as ferroelectric orders. PMID:21673668

  8. Kuzey Ege ve Marmara Denizi Kıyısal Yüzey Sularında Scyphomedusae ve Ctenophora Üzerine Yerinde Gözlemler.

    Directory of Open Access Journals (Sweden)

    Süleyman Mavili

    2015-12-01

    Full Text Available Skifomedüz ve ktenoforların dağılımı ve bolluğu, 1998 ve 2005 arasında yaz ve sonbahar dönemlerinde yerinde gözlemlerle incelenmiştir. Skifomedüzler (A. aurita, R. pulmo Kuzey Ege ve Marmara Denizi’nde geniş bir dağılım göstermiştir. Yazın baskın olan A. aurita sonbaharda azalmış, oysa R. pulmo bu dönemde belirgin olarak artmıştır. Ktenoforlar (M. leidyi, B. ovata Kuzey Ege’de bulunmamıştır. M. leidyi Marmara Denizi’nde 1999’da bol olarak bulunmuş, B. ovata’nın ortaya çıktığı 2000’de belirgin bir azalma göstermiştir. Her iki ktenofor da 2004 ve 2005’de çalışma bölgesinde bulunmamıştır. Bu da pek muhtemelen M. leidyi yoğunluğunda büyük bir azalmaya işaret etmektedir

  9. Understanding the Nature of VeLLOs Through Interferometric Millimeter Observations

    Science.gov (United States)

    Huard, Tracy L.; Pound, M. W.; Mundy, L. G.; Dunham, M. M.

    2013-01-01

    Since a new class of embedded sources, referred to as Very Low Luminosity Objects (VeLLOs), was discovered using Spitzer Space Telescope observations, the number of known VeLLOs has been slowly growing. Still, their nature remains unclear: they may be progenitors of typical low-mass stars or of brown dwarfs. The VeLLOs with millimeter observations demonstrate that they sustain outflows with a wide range of energetics, suggesting VeLLOs may represent an inhomogeneous group. For example, the large-scale outflow driven by a VeLLO in core IRAM 04191+1522 is three orders of magnitude stronger than the weak, compact outflow driven by VeLLO L1014-IRS, despite these sources having comparable luminosities. We have conducted a survey of eight confirmed and candidate VeLLOs, obtaining CO(2-1) and 1.3-mm continuum CARMA observations, to study their small-scale outflows and inner (< 3000 AU) envelopes. Our observations reveal previously undetected outflows and inner envelopes of 10-200 Jupiter masses. Since these envelopes represent reservoirs for future accretion, we identify which VeLLOs are likely protostars and which are likely proto-brown dwarfs based on these envelope masses.

  10. VE-cadherin interacts with cell polarity protein Pals1 to regulate vascular lumen formation.

    Science.gov (United States)

    Brinkmann, Benjamin F; Steinbacher, Tim; Hartmann, Christian; Kummer, Daniel; Pajonczyk, Denise; Mirzapourshafiyi, Fatemeh; Nakayama, Masanori; Weide, Thomas; Gerke, Volker; Ebnet, Klaus

    2016-09-15

    Blood vessel tubulogenesis requires the formation of stable cell-to-cell contacts and the establishment of apicobasal polarity of vascular endothelial cells. Cell polarity is regulated by highly conserved cell polarity protein complexes such as the Par3-aPKC-Par6 complex and the CRB3-Pals1-PATJ complex, which are expressed by many different cell types and regulate various aspects of cell polarity. Here we describe a functional interaction of VE-cadherin with the cell polarity protein Pals1. Pals1 directly interacts with VE-cadherin through a membrane-proximal motif in the cytoplasmic domain of VE-cadherin. VE-cadherin clusters Pals1 at cell-cell junctions. Mutating the Pals1-binding motif in VE-cadherin abrogates the ability of VE-cadherin to regulate apicobasal polarity and vascular lumen formation. In a similar way, deletion of the Par3-binding motif at the C-terminus of VE-cadherin impairs apicobasal polarity and vascular lumen formation. Our findings indicate that the biological activity of VE-cadherin in regulating endothelial polarity and vascular lumen formation is mediated through its interaction with the two cell polarity proteins Pals1 and Par3.

  11. Genetic dissection of Verticillium wilt resistance mediated by tomato Ve1.

    Science.gov (United States)

    Fradin, Emilie F; Zhang, Zhao; Juarez Ayala, Juan C; Castroverde, Christian D M; Nazar, Ross N; Robb, Jane; Liu, Chun-Ming; Thomma, Bart P H J

    2009-05-01

    Vascular wilt diseases caused by soil-borne pathogens are among the most devastating plant diseases worldwide. The Verticillium genus includes vascular wilt pathogens with a wide host range. Although V. longisporum infects various hosts belonging to the Cruciferaceae, V. dahliae and V. albo-atrum cause vascular wilt diseases in over 200 dicotyledonous species, including economically important crops. A locus responsible for resistance against race 1 strains of V. dahliae and V. albo-atrum has been cloned from tomato (Solanum lycopersicum) only. This locus, known as Ve, comprises two closely linked inversely oriented genes, Ve1 and Ve2, that encode cell surface receptor proteins of the extracellular leucine-rich repeat receptor-like protein class of disease resistance proteins. Here, we show that Ve1, but not Ve2, provides resistance in tomato against race 1 strains of V. dahliae and V. albo-atrum and not against race 2 strains. Using virus-induced gene silencing in tomato, the signaling cascade downstream of Ve1 is shown to require both EDS1 and NDR1. In addition, NRC1, ACIF, MEK2, and SERK3/BAK1 also act as positive regulators of Ve1 in tomato. In conclusion, Ve1-mediated resistance signaling only partially overlaps with signaling mediated by Cf proteins, type members of the receptor-like protein class of resistance proteins.

  12. Mutational analysis of the Ve1 immune receptor that mediates Verticillium resistance in tomato

    NARCIS (Netherlands)

    Zhang, Z.; Song, Y.; Liu, Chun-Ming; Thomma, B.P.H.J.

    2014-01-01

    Pathogenic Verticillium species are economically important plant pathogens that cause vascular wilt diseases in hundreds of plant species. The Ve1 gene of tomato confers resistance against race 1 strains of Verticillium dahliae and V. albo-atrum. Ve1 encodes an extracellular leucine-rich repeat (eLR

  13. Tomato Ve disease resistance genes encode cell surface-like receptors

    Science.gov (United States)

    Kawchuk, Lawrence M.; Hachey, John; Lynch, Dermot R.; Kulcsar, Frank; van Rooijen, Gijs; Waterer, Doug R.; Robertson, Albert; Kokko, Eric; Byers, Robert; Howard, Ronald J.; Fischer, Rainer; Prüfer, Dirk

    2001-01-01

    In tomato, Ve is implicated in race-specific resistance to infection by Verticillium species causing crop disease. Characterization of the Ve locus involved positional cloning and isolation of two closely linked inverted genes. Expression of individual Ve genes in susceptible potato plants conferred resistance to an aggressive race 1 isolate of Verticillium albo-atrum. The deduced primary structure of Ve1 and Ve2 included a hydrophobic N-terminal signal peptide, leucine-rich repeats containing 28 or 35 potential glycosylation sites, a hydrophobic membrane-spanning domain, and a C-terminal domain with the mammalian E/DXXXLφ or YXXφ endocytosis signals (φ is an amino acid with a hydrophobic side chain). A leucine zipper-like sequence occurs in the hydrophobic N-terminal signal peptide of Ve1 and a Pro-Glu-Ser-Thr (PEST)-like sequence resides in the C-terminal domain of Ve2. These structures suggest that the Ve genes encode a class of cell-surface glycoproteins with receptor-mediated endocytosis-like signals and leucine zipper or PEST sequences. PMID:11331751

  14. Plasmodium vivax sporozoite challenge in malaria-naïve and semi-immune Colombian volunteers

    DEFF Research Database (Denmark)

    Arévalo-Herrera, Myriam; Forero-Peña, David A.; Rubiano, Kelly

    2014-01-01

    induced in naïve and semi-immune volunteers by infected mosquito bites was compared. Methods: Seven malaria-naïve and nine semi-immune Colombian adults (n = 16) were subjected to the bites of 2-4 P. vivax sporozoite-infected Anopheles mosquitoes. Parasitemia levels, malaria clinical manifestations...

  15. Association Between Hypodensities Detected by Computed Tomography and Hematoma Expansion in Patients With Intracerebral Hemorrhage

    Science.gov (United States)

    Boulouis, Gregoire; Morotti, Andrea; Brouwers, H. Bart; Charidimou, Andreas; Jessel, Michael J.; Auriel, Eitan; Pontes-Neto, Octávio; Ayres, Alison; Vashkevich, Anastasia; Schwab, Kristin M.; Rosand, Jonathan; Viswanathan, Anand; Gurol, Mahmut E.; Greenberg, Steven M.; Goldstein, Joshua N.

    2017-01-01

    IMPORTANCE Hematoma expansion is a potentially modifiable predictor of poor outcome following an acute intracerebral hemorrhage (ICH). The ability to identify patients with ICH who are likeliest to experience hematoma expansion and therefore likeliest to benefit from expansion-targeted treatments remains an unmet need. Hypodensities within an ICH detected by noncontrast computed tomography (NCCT) have been suggested as a predictor of hematoma expansion. OBJECTIVE To determine whether hypodense regions, irrespective of their specific patterns, are associated with hematoma expansion in patients with ICH. DESIGN, SETTING, AND PARTICIPANTS We analyzed a large cohort of 784 patients with ICH (the development cohort; 55.6% female), examined NCCT findings for any hypodensity, and replicated our findings on a different cohort of patients (the replication cohort; 52.7% female). Baseline and follow-up NCCT data from consecutive patients with ICH presenting to a tertiary care hospital between 1994 and 2015 were retrospectively analyzed. Data analyses were performed between December 2015 and January 2016. MAIN OUTCOMES AND MEASURES Hypodensities were analyzed by 2 independent blinded raters. The association between hypodensities and hematoma expansion (>6 cm3 or 33% of baseline volume) was determined by multivariable logistic regression after controlling for other variables associated with hematoma expansion in univariate analyses with P ≤ .10. RESULTS A total of 1029 patients were included in the analysis. In the development and replication cohorts, 222 of 784 patients (28.3%) and 99 of 245 patients (40.4%; 321 of 1029 patients [31.2%]), respectively, had NCCT scans that demonstrated hypodensities at baseline (κ = 0.87 for interrater reliability). In univariate analyses, hypodensities were associated with hematoma expansion (86 of 163 patients with hematoma expansion had hypodensities [52.8%], whereas 136 of 621 patients without hematoma expansion had hypodensities [21

  16. Institutional Repository saber.ula.ve: A testimonial perspective

    CERN Document Server

    Briceno, Y; Nunez, L A; Salager-Meyer, F; Rojas, A; Torrens, R

    2009-01-01

    In this paper, we describe our decade-long experience of building and operating one of the most active Institutional Repository in the world: www.saber.ula.ve (University of the Andes, Merida-Venezuela). In order to share our experience with other institutions, we firstly explain the steps we followed to preserve and disseminate the scientific production of the University of Los Andes' researchers. We then present some recent quantitative results about our repository activities and we outline some methodological guidelines that could be applied in order to replicate similar experiences. These guidelines list the ingredients or building blocks as well as the processes followed for developing and maintaining the services of an Institutional Repository. These include technological infrastructure; institutional policies on preservation, publication and dissemination of knowledge; recommendations on incentives for open access publication; the process of selection, testing and adaptation of technological tools; th...

  17. Algılama ve Eğitim

    OpenAIRE

    ÜLGEN, GÜLTEN

    1983-01-01

    Hangi düzeyde öğretim yapılırsa yapılsın, konu ne olursa olsun ister genel bilgi, isterse bir disiplinle ilgili mesleğe hazırlayıcı nitelikte olsun eğitimcilerin ortak bir hedefi vardır: O da öğrencinin kendi gelişme kapasitesini etkili bir şekilde kullanabilmesidir. Bireyin gelişmesini sağlayan üç önemli kapasitesi vardır: (1) Algılama, (2) Hissetme ve (3) Yapma kapasiteleri. Bu üç kapasite bireyin çevresiyle etkileşim sürecinde biribirini de etkileyerek onun tüm gelişimini sağlar. O halde b...

  18. Festival du rire de Genève

    CERN Multimedia

    Staff Association

    2015-01-01

    Connaissez-vous le Festival du rire de Genève ? La deuxième édition aura lieu du 25 au 28 mars 2015 au Casino-Théâtre à Carouge. Côté programmation, Marc Donnet-Monay ouvre les festivités avant trois autres soirées de folie et d’humour que nous vous laissons le soin de découvrir dans le programme : http://www.rire-geneve.ch/#programme. Réduction de 30% sur l’achat de places pour les membres du personnel du CERN. Pour cela, il suffit de se rendre sur la billetterie en ligne de notre site : www.rire-geneve.ch et d’utiliser le code promotionnel. Contacter le secrétariat de l’Association du personnel (Staff.Association@cern.ch) pour connaitre ce code promotionnel.

  19. Power-law solutions for TeVeS

    CERN Document Server

    Batista, C E Magalhaes

    2009-01-01

    The dynamics of TeVeS in a homogeneous and isotropic universe is shown to be equivalent to the dynamics of an interacting two-component system, consisting of a scalar field and a "fluid", related to the matter part, with explicitly given coupling term. Scaling solutions (solutions with a constant ratio of the energy densities of both components) in the "Einstein frame" are found which are exponentially expanding or contracting with no remaining freedom for Bekenstein's $F$ function. In the "physical frame" these solutions are of the power-law type. An equivalent General Relativity (GR) picture of the dynamics suggests that it is the scalar field which plays the role of dark matter, while the "matter" has to mimic (phantom-type) dark energy.

  20. Université de Genève

    CERN Multimedia

    2008-01-01

    Ecole de physique - Département de physique nucléaire et corspusculaire 24, quai Ernest-Ansermet 1211 GENÈVE 4 Tél: (022) 379 62 73 - Fax: (022) 379 69 92 Wednesday 19 November 2008 PARTICLE PHYSICS SEMINAR at 17.00 hrs – Stückelberg Auditorium The Sudbury Neutrino Observatory: Early searches for new physics at the CMS experiment Dr Filip Moortgat, ETH Zurich The CMS experiment at the LHC will provide unprecedented opportunities to discover new forms of matter and energy. This talk will first introduce the CMS experiment, its physics potential and general analysis strategy. It is followed by examples of possible searches for new phenomena in CMS, including Higgs, SUSY, and other exotic particles, with early LHC data. Information: http://dpnc.unige.ch/seminaire/annonce.html Organizer : J.-S. Graulich

  1. Retraction: 'Effect of blonanserin on cognitive function in antipsychotic-naïve first-episode schizophrenia'.

    Science.gov (United States)

    Tenjin, Tomomi; Miyamoto, Seiya; Miyake, Nobumi; Ogino, Shin; Kitajima, Rei; Ojima, Kazuaki; Arai, Jun; Teramoto, Haruki; Tsukahara, Sachiko; Ito, Yukie; Tadokoro, Masanori; Anai, Kiriko; Funamoto, Yasuyuki; Kaneda, Yasuhiro; Sumiyoshi, Tomiki; Yamaguchi, Noboru

    2017-05-01

    The above article from Human Psychopharmacology, first published on 25 January 2012 in Wiley OnlineLibrary (onlinelibrary.wiley.com), and in Volume 90, pp. 90-100, has been retracted by agreement between the authors, the journal Editor in Chief, David Baldwin, and John Wiley & Sons Ltd. The retraction has been agreed following an investigation by the St Marianna University Ethics Committee which determined that the paper was not as originally designed and approved. Tenjin, T., Miyamoto, S., Miyake, N., Ogino, S., Kitajima, R., Ojima, K., … Yamaguchi, N. (2012). Effect of blonanserin on cognitive function in antipsychotic-naïve first-episode schizophrenia. Hum. Psychopharmacol Clin Exp, 27, 90-100. https://doi.org/10.1002/hup.1276. Copyright © 2017 John Wiley & Sons, Ltd.

  2. Thermal Expansion of LaCoO3

    Institute of Scientific and Technical Information of China (English)

    闫柏军; 张家芸; 刘建华

    2004-01-01

    High-temperature X-ray diffraction(HTXRD)measurements of LaCoO3 powder was carried out in a temperature range from 298 to 1273 K.The experimental data obtained were adopted to evaluate the lattice parameters and cell volume.In this temperature range,the linear and volume expansion coefficients calculated using these cell parameters are 24.160~23.610×10-6·K-1 and 59.601~63.218×10-6·K-1 respectively.There is no discontinuity found in the cell parameters through the proposed first-order transition at 1210 K.

  3. Social Dynamism and Sports / Toplumsal Dinamizm ve Spor

    Directory of Open Access Journals (Sweden)

    Ahmet Gökhan YAZICI

    2014-03-01

    Full Text Available Society is a living organism. It involves some dynamics on the basis of individual, group and society. Sports are one of the fundamental segments of social dynamism. Sports have a very important role in raising a healthy generation, in supporting social development, in the assurance of social justice, and in the establishment of a clean environment. Some factors that threaten the future of sports: a Doping b Rigged game c Violence The future of sports depends on the clearance of these handicaps. This is not impossible; however, it requires a rigid international collaboration and a constant campaign. Toplum yaşayan bir örgenliktir. Fert, grup ve toplum bazında bazı dinamiklere sahiptir. Toplumsal dinamiğin en temel sektörlerinden birisi de spordur. Spor sağlıklı bir neslin yetiştirilmesinde, toplumsal kalkınmanın desteklenmesinde, sosyal adaletin temininde, temiz bir çevrenin tesisinde çok önemli bir role sahiptir. Sporun geleceğini tehdit eden bazı faktörler bulunmaktadır. Bunlar; a. Doping b. Şike c. Şiddettir. Sporun geleceği bu handikaplardan kendisini temizlemesine bağlıdır. Bu imkânsız değildir. Fakat bu toleranssız, uluslararası işbirliği ve sürekli bir mücadeleyi gerektirmektedir.

  4. Pressurized electrolysis stack with thermal expansion capability

    Science.gov (United States)

    Bourgeois, Richard Scott

    2015-07-14

    The present techniques provide systems and methods for mounting an electrolyzer stack in an outer shell so as to allow for differential thermal expansion of the electrolyzer stack and shell. Generally, an electrolyzer stack may be formed from a material with a high coefficient of thermal expansion, while the shell may be formed from a material having a lower coefficient of thermal expansion. The differences between the coefficients of thermal expansion may lead to damage to the electrolyzer stack as the shell may restrain the thermal expansion of the electrolyzer stack. To allow for the differences in thermal expansion, the electrolyzer stack may be mounted within the shell leaving a space between the electrolyzer stack and shell. The space between the electrolyzer stack and the shell may be filled with a non-conductive fluid to further equalize pressure inside and outside of the electrolyzer stack.

  5. Novel thermal expansion of lead titanate

    Institute of Scientific and Technical Information of China (English)

    XING Xianran; DENG Jinxia; CHEN Jun; LIU Guirong

    2003-01-01

    Lattice parameters of lead titanate were precisely re-determined in the ternperature range of-150-950℃ by high precision XRPD measurements. It was clarified that there was no any evidence for a new phase transition at low temperatures. Tetragonal distortion strain decreases with temperature increasing. A novel thermal expansion was observed, positive thermal expansion from-150℃ to room temperature (RT) and above 490℃, and the negative thermal expansion in the temperature range of RT-490℃. A big jump of thermal expansion coefficient is attributed to the tetragonal-cubic phase transition. A rationalization for the negative thermal expansion of PbTiO3 is due to the decrease of anion-anion repulsion as polyhedra become more regular at heating. The mechanisms of positive and negative thermal expansions were elucidated as the same nature in the homogenous tetragonal phase at present case.

  6. Protein Oksidasyonun Biyokimyasal ve Moleküler mekanizması

    Directory of Open Access Journals (Sweden)

    Ender Buyukguzel

    2013-06-01

    Full Text Available Serbest amino asitler ve proteinlerdeki amino asit kökleri çeşitli reaktif oksijen ve azot türleri (ROT, RAT ve metal iyonlarının okside edici etkilerine karşı oldukça hassastırlar. ROT üretimi çevresel faktörlerin etkisi ile olduğu kadar hücresel metabolik aktiviteler sonucunda da gerçekleşir. ROT’lar karbohidrat, nükleik asit, lipid ve proteinler gibi hücrenin temel makromolekülleri ile etkileşebilir. Proteinler canlı organizmalarda yapısal ve işlevsel olarak önemli rolleri üstlenmiş biyomoleküller olduğundan bu makalede protein ve serbest amino asitlerin ROT aracılığı ile oksidasyonu üzerinde durulmuştur. Proteinlerin oksidasyonu sonucu aromatik grupların ve alifatik amino asit yan zincirlerinin hidroksilasyonu, aromatik amino asit köklerinin ve sülfidril gruplarının nitrolanması, metiyoninin sülfoksitlenmesi, aromatik ve primer amin gruplarının klorlanması ve bazı amino asit köklerinin karbonil türevlerine dönüşümü gerçekleşir. Oksidasyon aynı zamanda çapraz bağlı proteinlerin oluşumu ve polipeptit zincirinin kırılmasına da neden olarak sonuçta bazı radikallerin en önemlisi alkoksil radikallerinin oluşumunu sağlar. Ayrıca proteinlerin fonksiyonel grupları 2-alkenal, 4-hidroksi-2-alkenal, and ketoaldehid gibi çoklu doymamış yağ asitlerinin oksidasyon ürünleri ve bazı karbohidrat türevleri (karbohidrat eklenmesi veya karbohidratların oksidasyon ürünleri ile reaksiyona girerek inaktif türev bileşikleri oluştururlar. Diğer taraftan yaşlanma ve oksidatif hasara uğramış protein lipid ve nükleik asitlerin birikmesi arasında bir ilişki bulunmaktadır. Oksidatif olarak modifiye olmuş proteinlerin miktarında yaşın ilerlemesi ile birlikte artış olduğu ve protein oksidasyonunu azaltan faktörlerin aynı zamanda canlıların yaşam süresini uzattığı bilinmektedir. Ayrıca omurgalılarda diyabet, aterosklerosis, nörodejeneratif hastalıklar, kalp ve

  7. Effect of gas expansion on the front shape of a Taylor bubble: an experimental contribution

    Directory of Open Access Journals (Sweden)

    Santos Laura

    2014-03-01

    Full Text Available An experimental study where an individual Taylor bubble rises through water with different bubble volume expansion rates is presented with the (front bubble shape determination as main objective. A combination of two techniques, Particle Image Velocimetry (PIV and Pulsed Shadowgraphy (PS, was used to collect images for further treatment in order to characterize the liquid flow pattern in front of the bubble and the bubble shape. Processing the images acquired with pulsed illumination from behind the bubble it was possible to define with precision the bubble shape at different stages when it was expanding. The operation conditions used allowed a wide range of volume expansion rates (0 to 28.5 × 10-6 m3/s with a significant effect on the Taylor bubble velocity; increases in bubble velocity up to 21% were observed relatively to constant volume system condition. Nevertheless, it seems that the front shape of Taylor bubbles does not change significantly with the upward liquid flow rates induced by gas expansion, at least for the volume expansion rates used in the experiments.

  8. Anomalous thermal expansion in $\\alpha$-titanium

    OpenAIRE

    Souvatzis, P.; O. Eriksson; M. I. Katsnelson

    2007-01-01

    We provide a complete quantitative explanation for the anisotropic thermal expansion of hcp Ti at low temperature. The observed negative thermal expansion along the c-axis is reproduced theoretically by means of a parameter free theory which involves both the electron and phonon contributions to the free energy. The thermal expansion of titanium is calculated and found to be negative along the c-axis for temperatures below $\\sim$ 170 K, in good agreement with observations. We have identified ...

  9. Hydration and Thermal Expansion in Anatase Nanoparticles.

    Science.gov (United States)

    Zhu, He; Li, Qiang; Ren, Yang; Fan, Longlong; Chen, Jun; Deng, Jinxia; Xing, Xianran

    2016-08-01

    A tunable thermal expansion is reported in nanosized anatase by taking advantage of surface hydration. The coefficient of thermal expansion of 4 nm TiO2 along a-axis is negative with a hydrated surface and is positive without a hydrated surface. High-energy synchrotron X-ray pair distribution function analysis combined with ab initio calculations on the specific hydrated surface are carried out to reveal the local structure distortion that is responsible for the unusual negative thermal expansion.

  10. Hydration and Thermal Expansion in Anatase Nanoparticles

    Energy Technology Data Exchange (ETDEWEB)

    Zhu, He [Department of Physical Chemistry, University of Science and Technology Beijing, Beijing 100083 China; Li, Qiang [Department of Physical Chemistry, University of Science and Technology Beijing, Beijing 100083 China; Ren, Yang [Argonne National Laboratory, X-Ray Science Division, Argonne IL 60439 USA; Fan, Longlong [Department of Physical Chemistry, University of Science and Technology Beijing, Beijing 100083 China; Chen, Jun [Department of Physical Chemistry, University of Science and Technology Beijing, Beijing 100083 China; Deng, Jinxia [Department of Physical Chemistry, University of Science and Technology Beijing, Beijing 100083 China; Xing, Xianran [Department of Physical Chemistry, University of Science and Technology Beijing, Beijing 100083 China

    2016-06-06

    A tunable thermal expansion is reported in nanosized anatase by taking advantage of surface hydration. The coefficient of thermal expansion of 4 nm TiO2 along a-axis is negative with a hydrated surface and is positive without a hydrated surface. High-energy synchrotron X-ray pair distribution function analysis combined with ab initio calculations on the specific hydrated surface are carried out to reveal the local structure distortion that is responsible for the unusual negative thermal expansion.

  11. GAUSSIAN WHITE NOISE CALCULUS OF GENERALIZED EXPANSION

    Institute of Scientific and Technical Information of China (English)

    陈泽乾

    2002-01-01

    A new framework of Gaussian white noise calculus is established, in line with generalized expansion in [3, 4, 7]. A suitable frame of Fock expansion is presented on Gaussian generalized expansion functionals being introduced here, which provides the integral kernel operator decomposition of the second quantization of Koopman operators for chaotic dynamical systems, in terms of annihilation operators (e)t and its dual, creation operators (e)*t.

  12. Alternative Routes to Induce Naïve Pluripotency in Human Embryonic Stem Cells.

    Science.gov (United States)

    Duggal, Galbha; Warrier, Sharat; Ghimire, Sabitri; Broekaert, Dorien; Van der Jeught, Margot; Lierman, Sylvie; Deroo, Tom; Peelman, Luc; Van Soom, Ann; Cornelissen, Ria; Menten, Björn; Mestdagh, Pieter; Vandesompele, Jo; Roost, Matthias; Slieker, Roderick C; Heijmans, Bastiaan T; Deforce, Dieter; De Sutter, Petra; De Sousa Lopes, Susana Chuva; Heindryckx, Björn

    2015-09-01

    Human embryonic stem cells (hESCs) closely resemble mouse epiblast stem cells exhibiting primed pluripotency unlike mouse ESCs (mESCs), which acquire a naïve pluripotent state. Efforts have been made to trigger naïve pluripotency in hESCs for subsequent unbiased lineage-specific differentiation, a common conundrum faced by primed pluripotent hESCs due to heterogeneity in gene expression existing within and between hESC lines. This required either ectopic expression of naïve genes such as NANOG and KLF2 or inclusion of multiple pluripotency-associated factors. We report here a novel combination of small molecules and growth factors in culture medium (2i/LIF/basic fibroblast growth factor + Ascorbic Acid + Forskolin) facilitating rapid induction of transgene-free naïve pluripotency in hESCs, as well as in mESCs, which has not been shown earlier. The converted naïve hESCs survived long-term single-cell passaging, maintained a normal karyotype, upregulated naïve pluripotency genes, and exhibited dependence on signaling pathways similar to naïve mESCs. Moreover, they undergo global DNA demethylation and show a distinctive long noncoding RNA profile. We propose that in our medium, the FGF signaling pathway via PI3K/AKT/mTORC induced the conversion of primed hESCs toward naïve pluripotency. Collectively, we demonstrate an alternate route to capture naïve pluripotency in hESCs that is fast, reproducible, supports naïve mESC derivation, and allows efficient differentiation.

  13. Structure and thermal expansion of liquid bismuth

    Directory of Open Access Journals (Sweden)

    Mudry S.

    2015-12-01

    Full Text Available Experimental structural data for liquid Bi were used for estimation of the main structure parameters as well as the thermal expansion coefficient both in supercooled and superheated temperature ranges. It was shown that the equilibrium melt had a positive thermal expansion coefficient within a temperature range upon melting and a negative one at higher temperatures. The former was related to structure changes upon melting, whereas the latter with topologic disordering upon further heating. It was found that the superheated melt had a negative thermal expansion coefficient. The results obtained from structural data were compared with the thermal expansion coefficient calculated from the data of density for liquid Bi.

  14. TAYLOR EXPANSION METHOD FOR NONLINEAR EVOLUTION EQUATIONS

    Institute of Scientific and Technical Information of China (English)

    HE Yin-nian

    2005-01-01

    A new numerical method of integrating the nonlinear evolution equations, namely the Taylor expansion method, was presented. The standard Galerkin method can be viewed as the 0-th order Taylor expansion method; while the nonlinear Galerkin method can be viewed as the 1-st order modified Taylor expansion method. Moreover, the existence of the numerical solution and its convergence rate were proven. Finally, a concrete example,namely, the two-dimensional Navier-Stokes equations with a non slip boundary condition,was provided. The result is that the higher order Taylor expansion method is of the higher convergence rate under some assumptions about the regularity of the solution.

  15. Thermal expansion behavior of fluor-chlorapatite crystalline solutions

    Science.gov (United States)

    Hovis, G.; Harlov, D.; Gottschalk, M.; Hudacek, W.; Wildermuth, S.

    2009-04-01

    Apatite Ca5(PO4)3(F,Cl,OH,CO3) occurs widely as an accessory mineral in many igneous and metamorphic rocks and in nature displays a wide range of F-Cl-OH-CO3 mixtures (e.g., O'Reilly and Griffin, 2000) that have been used to interpret the role of fluids, e.g. Cl, F, and OH activities, during metamorphic and igneous processes (e.g., Harlov and Förster, 2002). It is important, therefore, to understand the thermodynamic behavior of these solid solutions, including their thermal expansion properties. Fluorapatite - chlorapatite samples were synthesized at the GFZ-Potsdam (Hovis, Harlov, Hahn and Steigert, 2007) using an adaptation of the molten flux method of Cherniak (2000). Dry CaF2 and CaCl2 (0.1 mole total) were mixed with Ca3(PO4)2 (0.03 moles), placed in a Pt crucible, equilibrated for 15 hours at 1375 °C, cooled to 1220 °C at 3 °C/hour, removed from the oven and cooled in air. Crystals were separated from the flux by boiling the quenched product in water. F:Cl fractions for each sample were determined via Rietveld refinement of X-ray powder diffraction data. Chemical homogeneity was confirmed by Rietveld refinement and high-contrast back-scattered electron imaging. Room-temperature unit-cell volumes were determined at the GFZ-Potsdam through Rietveld analysis of X-ray powder diffraction data and also at Lafayette College by standard unit-cell refinement techniques (Holland and Redfern, 1997) using NBS/NIST 640a Si as an internal standard. High-temperature unit-cell dimensions were calculated from X-ray powder diffraction data collected at Cambridge University from room temperature to 1000 °C on a Bruker D8 X-ray diffractometer. NBS Si again was utilized as an internal standard; high-temperature Si peak positions were taken from Parrish (1953). Results indicate that despite the considerable size difference between fluorine and chlorine ions, reflected by substantially different unit-cell sizes at room temperature, the coefficient of thermal expansion across

  16. Micromechanics analysis of thermal expansion and thermal pressurization of a hardened cement paste

    CERN Document Server

    Ghabezloo, Siavash

    2011-01-01

    The results of a macro-scale experimental study of the effect of heating on a fluid-saturated hardened cement paste are analysed using a multi-scale homogenization model. The analysis of the experimental results revealed that the thermal expansion coefficient of the cement paste pore fluid is anomalously higher than the one of pure bulk water. The micromechanics model is calibrated using the results of drained and undrained heating tests and permits the extrapolation of the experimentally evaluated thermal expansion and thermal pressurization parameters to cement pastes with different water-to-cement ratios. It permits also to calculate the pore volume thermal expansion coefficient f a which is difficult to evaluate experimentally. The anomalous pore fluid thermal expansion is also analysed using the micromechanics model.

  17. Üstün Zekâlı ve Yetenekli Öğrencilerin Okuma İlgisi, Tutumu ve Eleştirel Okuma Becerileri

    Directory of Open Access Journals (Sweden)

    Üzeyir Ogurlu

    2014-08-01

    Full Text Available Genel olarak üstün zekâlı ve yetenekli çocukların akranlarına göre okumaya erken başladıkları ve okumaya karşı ilgilerinin de yüksek olduğu belirtilmektedir. Eleştirel okuma becerisi, okuma alışkanlığının üst düzey becerileri arasında kabul edilmektedir. Bu araştırmada Bilim Sanat Merkezine devam eden 50 üstün zekâlı ve yetenekli öğrencinin okuma ilgileri, tutumu ve eleştirel okuma becerileri tespit edilmiştir. Ayrıca bu öğrencilerin okuma tutumları ile eleştirel okuma becerileri arasındaki ilişki incelenmiştir. Araştırma sonucunda üstün zekâlı ve yetenekli öğrencilerin orta ve üst düzey okuyan grup içerisinde yer aldıkları, okurken gizem ve bilim kurgu konularındaki roman türü kitapları tercih ettikleri belirlenmiştir. Bununla birlikte öğrencilerin tercihlerine göre kitap okudukları görülmüştür. Ayrıca, üstün zekâlı ve yetenekli öğrencilerin okuma tutumu ve eleştirel okuma becerilerinin yüksek olduğu ve okuma tutumu ile eleştirel okuma becerisi arasında yüksek bir ilişki olduğu sonucuna ulaşılmıştır. It was stated that gifted children read earlier than their peers and their reading interests and attitude were high. Critical reading skills are considered as one of the top-level reading skills. In this study, it was examined interest and attitudes in reading and critical reading skills of 50 gifted students. Also the relationship between critical reading skills and reading attitude was examined. It was found that gifted students read more books, prefer mystery and science fiction novel and read books according to their choice and preference. Also it was observed a high correlation between critical reading skills and reading attitude.

  18. Thermal expansion of an epoxy-glass microsphere composite

    Science.gov (United States)

    Price, H. L.; Burks, H. D.

    1977-01-01

    The thermal expansion of a composite of epoxy (diglycidyl ether of bisphenol A) and solid glass microspheres was investigated. The microspheres had surfaces which were either untreated or treated with a silicone release agent, an epoxy coupling agent, or a general purpose silane coupling agent. Both room temperature (about 300 K) and elevated temperature (about 475 K) cures were used for the epoxy. Two microsphere size ranges were used, about 50 microns, which is applicable in filled moldings, and about 125 microns, which is applicable as bond line spacers. The thermal expansion of the composites was measured from 300 to 350 K or from 300 to 500 K, depending on the epoxy cure temperature. Measurements were made on composites containing up to .6 volume fraction microspheres. Two predictive models, which required only the values of thermal expansion of the polymer and glass and their specific gravities, were tested against the experimental data. A finite element analysis was made of the thermal strain of a composite cell containing a single microsphere surrounded by a finite-thickness interface.

  19. [A case of hemimegalencephaly with slowly progressive expansion].

    Science.gov (United States)

    Yoshioka, Seiichiro; Sugai, Kenji; Fujikawa, Yoshinao; Komaki, Hirofumi; Nakagawa, Eiji; Sasaki, Masayuki

    2007-11-01

    We report a case of a male infant with refractory epilepsy, demonstrating hemimegalencephaly with slowly progressive expansion. The patient experienced his first seizure at 4 months of age. Subsequently, tonic seizures occurred very frequently despite extensive antiepileptic medications, and his development deteriorated. Cranial magnetic resonance imaging (MRI) at 4 months of age showed focal cortical dysplasia in the right opercular area. This focal lesion gradually expanded, and became thickened. Five years later, the dysplastic lesion occupied most of the right cerebral hemisphere and the volume of the right hemisphere increased, indicating hemimegalencephaly. He had profound motor and intellectual retardation. In the abnormal cerebral hemisphere, fluorodeoxyglucose-positron emission tomography (FDG-PET) showed marked hypometabolism, and ictal single photon emission computed tomography (SPECT) showed hyperperfusion, more pronounced in the right frontal area. These findings are consistent with a hemimegalencephaly. Hemimegalencephaly with such a progressive expansion has never been described previously. These findings are consistent with a hemimegalencephaly showing progressive expansion, which has never been described previously.

  20. Clinical response to eliglustat in treatment-naïve patients with Gaucher disease type 1: Post-hoc comparison to imiglucerase-treated patients enrolled in the International Collaborative Gaucher Group Gaucher Registry

    Directory of Open Access Journals (Sweden)

    Jennifer Ibrahim

    2016-09-01

    Full Text Available Eliglustat is a recently approved oral therapy in the United States and Europe for adults with Gaucher disease type 1 who are CYP2D6 extensive, intermediate, or poor metabolizers (>90% of patients that has been shown to decrease spleen and liver volume and increase hemoglobin concentrations and platelet counts in untreated adults with Gaucher disease type 1 and maintain these parameters in patients previously stabilized on enzyme replacement therapy. In a post-hoc analysis, we compared the results of eliglustat treatment in treatment-naïve patients in two clinical studies with the results of imiglucerase treatment among a cohort of treatment-naïve patients with comparable baseline hematologic and visceral parameters in the International Collaborative Gaucher Group Gaucher Registry. Organ volumes and hematologic parameters improved from baseline in both treatment groups, with a time course and degree of improvement in eliglustat-treated patients similar to imiglucerase-treated patients.

  1. Clinical response to eliglustat in treatment-naïve patients with Gaucher disease type 1: Post-hoc comparison to imiglucerase-treated patients enrolled in the International Collaborative Gaucher Group Gaucher Registry.

    Science.gov (United States)

    Ibrahim, Jennifer; Underhill, Lisa H; Taylor, John S; Angell, Jennifer; Peterschmitt, M Judith

    2016-09-01

    Eliglustat is a recently approved oral therapy in the United States and Europe for adults with Gaucher disease type 1 who are CYP2D6 extensive, intermediate, or poor metabolizers (> 90% of patients) that has been shown to decrease spleen and liver volume and increase hemoglobin concentrations and platelet counts in untreated adults with Gaucher disease type 1 and maintain these parameters in patients previously stabilized on enzyme replacement therapy. In a post-hoc analysis, we compared the results of eliglustat treatment in treatment-naïve patients in two clinical studies with the results of imiglucerase treatment among a cohort of treatment-naïve patients with comparable baseline hematologic and visceral parameters in the International Collaborative Gaucher Group Gaucher Registry. Organ volumes and hematologic parameters improved from baseline in both treatment groups, with a time course and degree of improvement in eliglustat-treated patients similar to imiglucerase-treated patients.

  2. Increased pulmonary vascular permeability as a cause of re-expansion edema in rabbits

    Energy Technology Data Exchange (ETDEWEB)

    Pavlin, D.J.; Nessly, M.L.; Cheney, F.W.

    1981-01-01

    In order to study the mechanism(s) underlying re-expansion edema, we measured the concentration of labeled albumin (RISA) in the extravascular, extracellular water (EVECW) of the lung as a measure of pulmonary vascular permeability. Re-expansion edema was first induced by rapid re-expansion of rabbit lungs that had been collapsed for 1 wk by pneumothorax. The RISA in EVECW was expressed as a fraction of its plasma concentration: (RISA)L/(RISA)PL. The volume of EVECW (ml/gm dry lung) was measured using a /sup 24/Na indicator. Results in re-expansion edema were compared with normal control lungs and with oleic acid edema as a model of permeability edema. In re-expanded lungs, EVECW (3.41 +/- SD 1.24 ml/g) and (RISA)L/(RISA)PL 0.84 +/- SD 0.15) were significantly increased when compared with normal control lungs (2.25 +/- 0.41 ml/g and 0.51 +/- 0.20, respectively). Results in oleic acid edema (5.66 +/- 2.23 ml/g and 0.84 +/- 0.23) were similar to re-expansion edema. This suggested that re-expansion edema is due to increased pulmonary vascular permeability caused by mechanical stresses applied to the lung during re-expansion.

  3. Excess molar volume of the acetonitrile + alcohol systems at 298.15 K. Part I: Density measurements for acetonitrile + methanol, + ethanol systems

    Directory of Open Access Journals (Sweden)

    SLOBODAN P. SERBANOVIC

    2002-09-01

    Full Text Available The excess molar volume VE of the binary liquid systems acetonitrile + methanol and acetonitrile + ethanol has been evaluated from density measurements at 298.15 K and at atmospheric pressure over the entire composition range. A vibrating tube densimeter, type Anton Paar DMA 55, was applied for these measurements. The Redlich–Kister equation was used to fit the experimental VE data.

  4. Chronic central vascular expansion induces hypokalemia in conscious primates

    Science.gov (United States)

    Moore-Ede, M. C.; Kass, D. A.

    1982-01-01

    Central vascular expansion maintained for four days in conscious squirrel monkeys reconciles the apparently conflicting short-term fluid and electrolyte responses to water immersion and atrial balloon distension, with those described for prolonged weightlessness during space flight. The monkeys are subjected to an increased lower body positive air pressure (LBPP) of 20 torr which produces a 3 cm water increase in the central venous pressure. Results show a marked increase in the urinary excretion of sodium, potassium, and water during the firxt six hours of LBPP, and the diuresis is maintained throughout the period of LBPP, although the levels of sodium and potassium excretion decline after 24 hours of exposure. Plasma aldosterone transiently drops within the first three hours of LBPP, and then regains normal levels within 24 hours, after which time these levels are maintained despite the continued LBPP stimulus. It is suggested that the normal plasma aldosterone levels observed in the experiments, as well as during space flight, might, epresent a relative hyposecretion in terms of volume homeostasis and a relative hypersecretion with respect to plasma potassium regulation. Thus, kaliuresis and marked natriuresis is confined primarly to the first 24 hours of central volume expansion, a period for which comparable data from space flights are lacking.

  5. Magnetic Clouds: Global and local expansion

    Science.gov (United States)

    Gulisano, Adriana; Demoulin, Pascal; Soledad Nakwacki, Ms Maria; Dasso, Sergio; Emilia Ruiz, Maria

    Magnetic clouds (MCs) are magnetized objects forming flux ropes, which are expelled from the Sun and travel through the heliosphere, transporting important amounts of energy, mass, magnetic flux, and magnetic helicity from the Sun to the interplanetary medium. To know the detailed dynamical evolution of MCs is very useful to improve the knowledge of solar processes, for instance from linking a transient solar source with its interplanetary manifestation. During its travel, and mainly due to the decrease of the total (magnetic plus thermal) pressure in the surrounding solar wind, MCs are objects in expansion. However, the detailed magnetic structure and the dynamical evolution of MCs is still not fully known. Even the identification of their boundaries is an open question in some cases. In a previous work we have shown that from onepoint observations of the bulk velocity profile, it is possible to infer the 'local' expansion rate for a given MC, i.e., the expansion rate while the MC is observed by the spacecraft. By the another hand, and from the comparison of sizes for different MCs observed at different heliodistances, it is possible to quantify an 'average' expansion law (i.e., a global expansion). In this work, in order to study the variability of the 'local' expansion with respect to the 'average' expansion of MCs during their travel, we present results and a comparison between both approaches. We make a detailed study of one-point observations (magnetic and bulk velocity) using a set of MCs and we get the 'local' expansion rate for each studied event. We compare the obtained 'local' expansion rates with the 'average' expansion law, and also with the expansion rates for the stationary solar wind.

  6. Biyodizel ve Karışımlarının Kullanıldığı bir Dizel Motorda Performans ve Emisyon Analizi

    Directory of Open Access Journals (Sweden)

    Ahmet Necati ÖZSEZEN

    2009-02-01

    Full Text Available Bu çalışmada, atık palmiye yağı kökenli biyodizel ve petrol kökenli dizel yakıtı (PKDY ile karışımlarının, bir dizel motordaki performans ve emisyon karakteristikleri üç boyutlu haritalar üzerinden analiz edilmiştir. Biyodizel ve karışımlarının performans ve emisyon karakterlerini belirlemek amacıyla, motor tam yük ve değişik devir testlerine tabi tutulmuştur. Analiz sonucunda, karışımdaki biyodizel oranı arttıkça PKDY'a göre özgül yakıt tüketiminde artış olduğu, motorun döndürme momentinde ise azalma meydana geldiği tespit edilmiştir. Emisyon analizi sonucunda ise, karışımdaki biyodizel oranı ile ilişkili olarak PKDY'a kıyasla yanmamış hidrokarbon (HC, karbon monoksit (CO ve duman koyuluğu emisyonlarında iyileşmeler olduğu, bununla birlikte karbon dioksit (CO2 ve azot oksit (NOx emisyonlarının motor devrine göre kararlı bir yapı sergilemediği belirlenmiştir.

  7. Brain volume reductions in adolescent heavy drinkers.

    Science.gov (United States)

    Squeglia, Lindsay M; Rinker, Daniel A; Bartsch, Hauke; Castro, Norma; Chung, Yoonho; Dale, Anders M; Jernigan, Terry L; Tapert, Susan F

    2014-07-01

    Brain abnormalities in adolescent heavy drinkers may result from alcohol exposure, or stem from pre-existing neural features. This longitudinal morphometric study investigated 40 healthy adolescents, ages 12-17 at study entry, half of whom (n=20) initiated heavy drinking over the 3-year follow-up. Both assessments included high-resolution magnetic resonance imaging. FreeSurfer was used to segment brain volumes, which were measured longitudinally using the newly developed quantitative anatomic regional change analysis (QUARC) tool. At baseline, participants who later transitioned into heavy drinking showed smaller left cingulate, pars triangularis, and rostral anterior cingulate volume, and less right cerebellar white matter volumes (pteens. Over time, participants who initiated heavy drinking showed significantly greater volume reduction in the left ventral diencephalon, left inferior and middle temporal gyrus, and left caudate and brain stem, compared to substance-naïve youth (pbrain regions in future drinkers and greater brain volume reduction in subcortical and temporal regions after alcohol use was initiated. This is consistent with literature showing pre-existing cognitive deficits on tasks recruited by frontal regions, as well as post-drinking consequences on brain regions involved in language and spatial tasks. Published by Elsevier Ltd.

  8. 76 FR 24883 - DNB Exports LLC, and AFI Elektromekanikanik Ve Elektronik San. Tic. Ltd. Sti. v. Barsan Global...

    Science.gov (United States)

    2011-05-03

    ... DNB Exports LLC, and AFI Elektromekanikanik Ve Elektronik San. Tic. Ltd. Sti. v. Barsan Global Lojistiks Ve Gumruk Musavirligi A.S., Barsan International, Inc., and Impexia Inc.; Notice of Filing of... Commission (``Commission'') by DNB Exports LLC (``DNB''), and AFI Elektromekanikanik Ve Elektronik San....

  9. Primordial vorticity and gradient expansion

    CERN Document Server

    Giovannini, Massimo

    2012-01-01

    The evolution equations of the vorticities of the electrons, ions and photons in a pre-decoupling plasma are derived, in a fully inhomogeneous geometry, by combining the general relativistic gradient expansion and the drift approximation within the Adler-Misner-Deser decomposition. The vorticity transfer between the different species is discussed in this novel framework and a set of general conservation laws, connecting the vorticities of the three-component plasma with the magnetic field intensity, is derived. After demonstrating that a source of large-scale vorticity resides in the spatial gradients of the geometry and of the electromagnetic sources, the total vorticity is estimated to lowest order in the spatial gradients and by enforcing the validity of the momentum constraint. By acknowledging the current bounds on the tensor to scalar ratio in the (minimal) tensor extension of the $\\Lambda$CDM paradigm the maximal comoving magnetic field induced by the total vorticity turns out to be, at most, of the or...

  10. A Proposed Stochastic Finite Difference Approach Based on Homogenous Chaos Expansion

    Directory of Open Access Journals (Sweden)

    O. H. Galal

    2013-01-01

    Full Text Available This paper proposes a stochastic finite difference approach, based on homogenous chaos expansion (SFDHC. The said approach can handle time dependent nonlinear as well as linear systems with deterministic or stochastic initial and boundary conditions. In this approach, included stochastic parameters are modeled as second-order stochastic processes and are expanded using Karhunen-Loève expansion, while the response function is approximated using homogenous chaos expansion. Galerkin projection is used in converting the original stochastic partial differential equation (PDE into a set of coupled deterministic partial differential equations and then solved using finite difference method. Two well-known equations were used for efficiency validation of the method proposed. First one being the linear diffusion equation with stochastic parameter and the second is the nonlinear Burger's equation with stochastic parameter and stochastic initial and boundary conditions. In both of these examples, the probability distribution function of the response manifested close conformity to the results obtained from Monte Carlo simulation with optimized computational cost.

  11. Negative thermal expansion materials: technological key for control of thermal expansion

    OpenAIRE

    Koshi Takenaka

    2012-01-01

    Most materials expand upon heating. However, although rare, some materials contract upon heating. Such negative thermal expansion (NTE) materials have enormous industrial merit because they can control the thermal expansion of materials. Recent progress in materials research enables us to obtain materials exhibiting negative coefficients of linear thermal expansion over −30 ppm K−1. Such giant NTE is opening a new phase of control of thermal expansion in composites. Specifically examining pra...

  12. The Expansion Postponement in Pure Type Systems

    Institute of Scientific and Technical Information of China (English)

    宋方敏

    1997-01-01

    The expansion postponement problem in Pure Type Systems is an open problem raised by R.Pollack in 1992.In this paper,the author presents a set of necessary and sufficient conditions for this problem and a set of sufficient conditions for it.The author also gives some properties for pure typ systems without the expansion rule.

  13. Multipole expansion method for supernova neutrino oscillations

    Energy Technology Data Exchange (ETDEWEB)

    Duan, Huaiyu; Shalgar, Shashank, E-mail: duan@unm.edu, E-mail: shashankshalgar@unm.edu [Department of Physics and Astronomy, University of New Mexico, Albuquerque, NM 87131 (United States)

    2014-10-01

    We demonstrate a multipole expansion method to calculate collective neutrino oscillations in supernovae using the neutrino bulb model. We show that it is much more efficient to solve multi-angle neutrino oscillations in multipole basis than in angle basis. The multipole expansion method also provides interesting insights into multi-angle calculations that were accomplished previously in angle basis.

  14. Finnish Higher Education Expansion and Regional Policy

    Science.gov (United States)

    Saarivirta, Toni

    2010-01-01

    This paper concentrates on the expansion of Finnish higher education between the 1960s and 1970s, exposes its background in the light of the policy decisions that were made, compares the unique features of this expansion with those of certain other countries, discusses the impact of the controlled "top down" governance of higher…

  15. Flash Expansion Threshold in Whirligig Swarms.

    Directory of Open Access Journals (Sweden)

    William L Romey

    Full Text Available In the selfish herd hypothesis, prey animals move toward each other to avoid the likelihood of being selected by a predator. However, many grouped animals move away from each other the moment before a predator attacks. Very little is known about this phenomenon, called flash expansion, such as whether it is triggered by one individual or a threshold and how information is transferred between group members. We performed a controlled experiment with whirligig beetles in which the ratio of sighted to unsighted individuals was systematically varied and emergent flash expansion was measured. Specifically, we examined: the percentage of individuals in a group that startled, the resulting group area, and the longevity of the flash expansion. We found that one or two sighted beetles in a group of 24 was not enough to cause a flash expansion after a predator stimulus, but four sighted beetles usually initiated a flash expansion. Also, the more beetles that were sighted the larger the resulting group area and the longer duration of the flash expansion. We conclude that flash expansion is best described as a threshold event whose adaptive value is to prevent energetically costly false alarms while quickly mobilizing an emergent predator avoidance response. This is one of the first controlled experiments of flash expansion, an important emergent property that has applications to understanding collective motion in swarms, schools, flocks, and human crowds. Also, our study is a convincing demonstration of social contagion, how the actions of one individual can pass through a group.

  16. A reduced volumetric expansion factor plot

    Science.gov (United States)

    Hendricks, R. C.

    1979-01-01

    A reduced volumetric expansion factor plot has been constructed for simple fluids which is suitable for engineering computations in heat transfer. Volumetric expansion factors have been found useful in correlating heat transfer data over a wide range of operating conditions including liquids, gases and the near critical region.

  17. Earnings Returns to the British Education Expansion

    Science.gov (United States)

    Devereux, Paul J.; Fan, Wen

    2011-01-01

    We study the effects of the large expansion in British educational attainment that took place for cohorts born between 1970 and 1975. Using the Quarterly Labour Force Survey, we find that the expansion caused men to increase education by about a year on average and gain about 8% higher wages; women obtained a slightly greater increase in education…

  18. The heavy quark expansion of QCD

    Energy Technology Data Exchange (ETDEWEB)

    Falk, A.F. [Johns Hopkins Univ., Baltimore, MD (United States). Dept. of Physics and Astronomy

    1997-06-01

    These lectures contain an elementary introduction to heavy quark symmetry and the heavy quark expansion. Applications such as the expansion of heavy meson decay constants and the treatment of inclusive and exclusive semileptonic B decays are included. Heavy hadron production via nonperturbative fragmentation processes is also discussed. 54 refs., 7 figs.

  19. Expansion techniques for collisionless stellar dynamical simulations

    Energy Technology Data Exchange (ETDEWEB)

    Meiron, Yohai [Kavli Institute for Astronomy and Astrophysics at Peking University, Beijing 100871 (China); Li, Baile; Holley-Bockelmann, Kelly [Department of Physics and Astronomy, Vanderbilt University, Nashville, TN 37235 (United States); Spurzem, Rainer, E-mail: ymeiron@pku.edu.cn [National Astronomical Observatories of China, Chinese Academy of Sciences, Beijing 100012 (China)

    2014-09-10

    We present graphics processing unit (GPU) implementations of two fast force calculation methods based on series expansions of the Poisson equation. One method is the self-consistent field (SCF) method, which is a Fourier-like expansion of the density field in some basis set; the other method is the multipole expansion (MEX) method, which is a Taylor-like expansion of the Green's function. MEX, which has been advocated in the past, has not gained as much popularity as SCF. Both are particle-field methods and optimized for collisionless galactic dynamics, but while SCF is a 'pure' expansion, MEX is an expansion in just the angular part; thus, MEX is capable of capturing radial structure easily, while SCF needs a large number of radial terms. We show that despite the expansion bias, these methods are more accurate than direct techniques for the same number of particles. The performance of our GPU code, which we call ETICS, is profiled and compared to a CPU implementation. On the tested GPU hardware, a full force calculation for one million particles took ∼0.1 s (depending on expansion cutoff), making simulations with as many as 10{sup 8} particles fast for a comparatively small number of nodes.

  20. CONCEPT OF TISSUE EXPANSION IN RECONSTRUCTIVE SURGERY

    Directory of Open Access Journals (Sweden)

    Sheeja Rajan

    2015-01-01

    Full Text Available BACKGROUND: Tissue expansion is a unique reconstructive option in the armamentarium of a reconstructive surgeon whereby skin and soft tissues of our body can be stretched to large dimensions for wound coverage. The basis for such stretch ability lies in the inherent viscoelastic properties of skin. AIMS: This paper explores the prospects of using tissue expanders to reconstruct defects arising due to a kaleidoscope of pathological conditions including burns scars, post traumatic scars, congenital anomalies like hairy nevus, involutional scars in haemangioma as well as in post mastectomy breast reconstruction . MATERIALS AND METHODS: Our experience with tissue expansion in 14 patients over 24 months is presented. Tissue expanders made of silicone in sizes from 100 - 250ml, of round, rectangular or croissant (crescent shapes have been used. Areas expanded include scalp, forehead, neck, abdomen and forearm. Multiple expanders have been used when possible. Average expansion time was 8 - 12 weeks and the expanded tissue was transferred as advancement flaps. RESULTS AND CONCLUSIONS: Tissue expansion was successfully completed in 13 patients. Expansion had to be aborted in 1 paediatric patient undergoing neck expansion due to infection. Implant failure occurred in 1 patient during serial expansion. Nevertheless, in our experience tissue expan sion is an invaluable reconstructive tool to give excellent donor tissue with colour and texture match in countless situations demanding aesthetic and functional reconstruction. KEYWORDS: Burns scars, Reconstruction, Tissue expansion .

  1. Virial expansion coefficients in the harmonic approximation

    DEFF Research Database (Denmark)

    R. Armstrong, J.; Zinner, Nikolaj Thomas; V. Fedorov, D.

    2012-01-01

    The virial expansion method is applied within a harmonic approximation to an interacting N-body system of identical fermions. We compute the canonical partition functions for two and three particles to get the two lowest orders in the expansion. The energy spectrum is carefully interpolated...

  2. Perturbative expansion of Chern-Simons theory

    OpenAIRE

    SAWON, Justin

    2005-01-01

    An overview of the perturbative expansion of the Chern--Simons path integral is given. The main goal is to describe how trivalent graphs appear: as they already occur in the perturbative expansion of an analogous finite-dimensional integral, we discuss this case in detail.

  3. VeA of Aspergillus niger increases spore dispersing capacity by impacting conidiophore architecture.

    Science.gov (United States)

    Wang, Fengfeng; Dijksterhuis, Jan; Wyatt, Timon; Wösten, Han A B; Bleichrodt, Robert-Jan

    2015-01-01

    Aspergillus species are highly abundant fungi worldwide. Their conidia are among the most dominant fungal spores in the air. Conidia are formed in chains on the vesicle of the asexual reproductive structure called the conidiophore. Here, it is shown that the velvet protein VeA of Aspergillus niger maximizes the diameter of the vesicle and the spore chain length. The length and width of the conidiophore stalk and vesicle were reduced nearly twofold in a ΔveA strain. The latter implies a fourfold reduced surface area to develop chains of spores. Over and above this, the conidial chain length was approximately fivefold reduced. The calculated 20-fold reduction in formation of conidia by ΔveA fits the 8- to 17-fold decrease in counted spore numbers. Notably, morphology of the ΔveA conidiophores of A. niger was very similar to that of wild-type Aspergillus sydowii. This suggests that VeA is key in conidiophore architecture diversity in the fungal kingdom. The finding that biomass formation of the A. niger ΔveA strain was reduced twofold shows that VeA not only impacts dispersion capacity but also colonization capacity of A. niger.

  4. Fibroblast growth factor signaling potentiates VE-cadherin stability at adherens junctions by regulating SHP2.

    Directory of Open Access Journals (Sweden)

    Kunihiko Hatanaka

    Full Text Available BACKGROUND: The fibroblast growth factor (FGF system plays a critical role in the maintenance of vascular integrity via enhancing the stability of VE-cadherin at adherens junctions. However, the precise molecular mechanism is not well understood. In the present study, we aimed to investigate the detailed mechanism of FGF regulation of VE-cadherin function that leads to endothelial junction stabilization. METHODS AND FINDINGS: In vitro studies demonstrated that the loss of FGF signaling disrupts the VE-cadherin-catenin complex at adherens junctions by increasing tyrosine phosphorylation levels of VE-cadherin. Among protein tyrosine phosphatases (PTPs known to be involved in the maintenance of the VE-cadherin complex, suppression of FGF signaling reduces SHP2 expression levels and SHP2/VE-cadherin interaction due to accelerated SHP2 protein degradation. Increased endothelial permeability caused by FGF signaling inhibition was rescued by SHP2 overexpression, indicating the critical role of SHP2 in the maintenance of endothelial junction integrity. CONCLUSIONS: These results identify FGF-dependent maintenance of SHP2 as an important new mechanism controlling the extent of VE-cadherin tyrosine phosphorylation, thereby regulating its presence in adherens junctions and endothelial permeability.

  5. Tulum Peynirlerinden izole Edilen Lactococcus lactis subsp. lactis YBML9 ve

    Directory of Open Access Journals (Sweden)

    Yasin TUNCER

    2009-04-01

    Full Text Available Bu çalısmanın amacı tulum peynirlerinden izole edilen Lactococcus lactis suslarının fenotipik tanısı ve bu suslar tarafından üretilen bakteriyosinlerin kısmi karakterizasyonlarıdır. Bu amaçla Türkiye'nin sekiz farklı ilinden (Ankara, Antalya, Burdur, Denizli, Erzincan, Isparta, İstanbul ve İzmir yöresel pazarlardan toplanan 60 adet tulum peyniri örneginden 40 adet Lactococcus lactis susu (31 adet L. lactis subsp. lactis ve 9 adet L. lactis subsp. cremoris izole edildi. 40 adet L. lactis susu içerisinden, 2 adet L. lactis subsp. lactis (YBML9 ve YBML21 susu bakteriyosin üretme yeteneginde bulundu. L. lactis subsp. lactis YBML9 ve YBML21 susları tarafından üretilen bakteriyosinler, farklı enzim, pH ve sıcaklık uygulamaları sonucu; sırasıyla nisin ve laktisin 481 olarak tanımlandı.

  6. Development of Soda Residue Concrete Expansion Agent

    Institute of Scientific and Technical Information of China (English)

    WANG Bao-min; WANG Li-jiu; M F Mohd Zain; F C Lai

    2003-01-01

    A new type of concrete expansion agent has been successfully developed for the first time in the world by utilizing an industrial waste residue-soda residue and an industrial wasteliquor.Adding 3%-6% of the agent into Portland cement enables a shrinkage-compensating concrete to be prepared.Mortar and concrete containing this expansion agent have better shrinkage-compensating and mechanical properties.The raw materials component,production process,technical properties,micro-analysis of mortar made with this expansion agent,mechanism of expansion and research results are described in this article.The experimental results show that the new type of concrete expansion agent accords with the standard and its main mineral component is xCaO-ySO3-zAl2O3.

  7. Business information query expansion through semantic network

    Science.gov (United States)

    Gong, Zhiguo; Muyeba, Maybin; Guo, Jingzhi

    2010-02-01

    In this article, we propose a method for business information query expansions. In our approach, hypernym/hyponymy and synonym relations in WordNet are used as the basic expansion rules. Then we use WordNet Lexical Chains and WordNet semantic similarity to assign terms in the same query into different groups with respect to their semantic similarities. For each group, we expand the highest terms in the WordNet hierarchies with hypernym and synonym, the lowest terms with hyponym and synonym and all other terms with only synonym. In this way, the contradictory caused by full expansion can be well controlled. Furthermore, we use collection-related term semantic network to further improve the expansion performance. And our experiment reveals that our solution for query expansion can improve the query performance dramatically.

  8. Maxwell superalgebras and Abelian semigroup expansion

    Energy Technology Data Exchange (ETDEWEB)

    Concha, P.K.; Rodríguez, E.K. [Departamento de Física, Universidad de Concepción, Casilla 160-C, Concepción (Chile); Dipartimento di Scienza Applicata e Tecnologia (DISAT), Politecnico di Torino, Corso Duca degli Abruzzi 24, 10129 Torino (Italy); Istituto Nazionale di Fisica Nucleare (INFN), Sezione di Torino, Via Pietro Giuria, 1, 10125 Torino (Italy)

    2014-09-15

    The Abelian semigroup expansion is a powerful and simple method to derive new Lie algebras from a given one. Recently it was shown that the S-expansion of so(3,2) leads us to the Maxwell algebra M. In this paper we extend this result to superalgebras, by proving that different choices of abelian semigroups S lead to interesting D=4 Maxwell Superalgebras. In particular, the minimal Maxwell superalgebra sM and the N-extended Maxwell superalgebra sM{sup (N)} recently found by the Maurer–Cartan expansion procedure, are derived alternatively as an S-expansion of osp(4|N). Moreover, we show that new minimal Maxwell superalgebras type sM{sub m+2} and their N-extended generalization can be obtained using the S-expansion procedure.

  9. Maxwell superalgebras and Abelian semigroup expansion

    Directory of Open Access Journals (Sweden)

    P.K. Concha

    2014-09-01

    Full Text Available The Abelian semigroup expansion is a powerful and simple method to derive new Lie algebras from a given one. Recently it was shown that the S-expansion of so(3,2 leads us to the Maxwell algebra M. In this paper we extend this result to superalgebras, by proving that different choices of abelian semigroups S lead to interesting D=4 Maxwell Superalgebras. In particular, the minimal Maxwell superalgebra sM and the N-extended Maxwell superalgebra sM(N recently found by the Maurer–Cartan expansion procedure, are derived alternatively as an S-expansion of osp(4|N. Moreover, we show that new minimal Maxwell superalgebras type sMm+2 and their N-extended generalization can be obtained using the S-expansion procedure.

  10. Isparta İlinde Gülün Üretim Girdileri, Maliyeti ve

    Directory of Open Access Journals (Sweden)

    V Demircan

    2009-04-01

    Full Text Available Bu araştırmanın amacı, Isparta ilindeki gülün tesis ve üretim dönemindeki girdileri, maliyeti ve karlılık durumunu belirlemektir. Çalışma Isparta Merkez, Atabey, Keçiborlu ve Gönen ilçelerinde gül üretiminin yoğun olduğu köylerde 2002-2003 üretim döneminde yürütülmüştür. Araştırmada kullanılan veriler 109 gül üreticisinden anket yöntemi ile elde edilmiştir. Araştırma sonuçlarına göre, işletmelerde dekara kullanılan işgücü ve makine çekigücü tesis döneminde sırasıyla 60.27 ve 3.62 saat, üretim döneminde ise sırasıyla 147.29 ve 5.62 saat olduğu saptanmıştır. İncelenen işletmelerde dekara toplam tesis masrafları 659.35 YTL ve üretim masrafları 609.49 YTL olarak hesaplanmıştır. Gül üretiminde elde edilen brüt, net ve oransal kar sırasıyla 557.38 YTL, 373.68 YTL ve 1.61 olarak belirlenmiştir.

  11. Density-functional expansion methods: evaluation of LDA, GGA, and meta-GGA functionals and different integral approximations.

    Science.gov (United States)

    Giese, Timothy J; York, Darrin M

    2010-12-28

    We extend the Kohn-Sham potential energy expansion (VE) to include variations of the kinetic energy density and use the VE formulation with a 6-31G* basis to perform a "Jacob's ladder" comparison of small molecule properties using density functionals classified as being either LDA, GGA, or meta-GGA. We show that the VE reproduces standard Kohn-Sham DFT results well if all integrals are performed without further approximation, and there is no substantial improvement in using meta-GGA functionals relative to GGA functionals. The advantages of using GGA versus LDA functionals becomes apparent when modeling hydrogen bonds. We furthermore examine the effect of using integral approximations to compute the zeroth-order energy and first-order matrix elements, and the results suggest that the origin of the short-range repulsive potential within self-consistent charge density-functional tight-binding methods mainly arises from the approximations made to the first-order matrix elements.

  12. Renormalized Volume

    CERN Document Server

    Gover, A Rod

    2016-01-01

    For any conformally compact manifold with hypersurface boundary we define a canonical renormalized volume functional and compute an explicit, holographic formula for the corresponding anomaly. For the special case of asymptotically Einstein manifolds, our method recovers the known results. The anomaly does not depend on any particular choice of regulator, but the coefficients of divergences do. We give explicit formulae for these divergences valid for any choice of regulating hypersurface; these should be relevant to recent studies of quantum corrections to entanglement entropies. The anomaly is expressed as a conformally invariant integral of a local Q-curvature that generalizes the Branson Q-curvature by including data of the embedding. In each dimension this canonically defines a higher dimensional generalization of the Willmore energy/rigid string action. We show that the variation of these energy functionals is exactly the obstruction to solving a singular Yamabe type problem with boundary data along the...

  13. Talent management ve vybrané společnosti

    OpenAIRE

    Šimonová, Lucie

    2015-01-01

    Tato diplomová práce se zaměřuje na oblast Talent managementu, přičemž její první část je věnována předložení teoretických poznatků, které se týkají vymezení a popisu základních pojmů jako je „talent“, „Talent management“ či „motivace“. Tyto poznatky jsou následně využity při zpracování části praktické, a to ve spolupráci s vybranou společností, jež má o zavedení Talent managementu zájem. This master’s thesis is focused on Talent management. First part is devoted to theoretical knowledge w...

  14. Université de Genève

    CERN Multimedia

    2008-01-01

    Ecole de physique - Département de physique nucléaire et corspusculaire 24, quai Ernest-Ansermet 1211 GENÈVE 4 Tél: (022) 379 62 73 - Fax: (022) 379 69 92 Wednesday 17 décembre 2008 PARTICLE PHYSICS SEMINAR at 17.00 hrs – Stückelberg Auditorium Bent crystals: a long story and its new frontiers by Dr Michela Prest / Universita degli Studi dell’Insubria, sede di Como When a particle physicist hears the world "crystal", he usually thinks of calorimeters, silicon detectors, a state of matter. When he hears the word "magnet", he thinks of bulky, heavy objects. In 1976, E. H. Tsyganov experimentally demonstrated how a bent crystal 1 mm thick, a couple of mm wide and a few cm high can steer particles as a dipole of several tens of Tesla. Crystals and the channelling phenomena have been studied for around 30 years. Hadron beam collimation has been immediately identified as their main application and the understanding of the physics of crystals and their experimental stu...

  15. EMILY BRONTE ve “UĞULTULU TEPELER”

    OpenAIRE

    DOĞAN, Ülfet

    2008-01-01

    Emily Bronte, 1811 yılında fakir bir ailenin beşinci çocuğu olarak dünyaya gelmiş bir İngiliz yazardır. Emily’nin çocukken annesi ölmüş, kendisi de fiziksel ve akli sıkıntılar çekmiştir. Yaşadığı çevrenin vermiş olduğu yalnızlık duygusuyla kendisine bir fantezi dünyası geliştirip, farklı bir üslupla tek bir roman ele almıştır. Bu romanında Gotik roman özellikleriyle karşılaşırken, diğer bir taraftan da yazarın hayatı hakkında bazı ipuçları elde ederiz. Diğer Victoria Çağı romanlarından fa...

  16. Université de Genève

    CERN Multimedia

    2008-01-01

    Ecole de physique - Département de physique nucléaire et corspusculaire 24, quai Ernest-Ansermet - 1211 GENÈVE 4 Tél: (022) 379 62 73 - Fax: (022) 379 69 92 Lundi 8 décembre 2008 PARTICLE PHYSICS SEMINAR at 17.00 hrs – Stückelberg Auditorium The Galaxy in a new light: High energy gamma ray astronomy with H.E.S.S. Prof. Werner Hofmann / MPI für Kernphysik, Heidelberg During its first years of operation, the H.E.S.S. array of imaging atmospheric Cherenkov telescopes has revealed a sky full of sources of very high energy gamma rays and has demonstrated the great power of the Cherenkov technique for exploring non-thermal processes in the Universe. High-energy gamma ray astronomy is now delivering sky maps, sources with resolved morphology, and high-resolution light curves, joining up with mainstream astronomy. The talk will illustrate some of the key results from H.E.S.S., mention some of the open questions, and present ideas for the next-generation CTA observatory. Organizer : Prof. Markus Büttiker W...

  17. The interplays among technology and content, immersant and VE

    Science.gov (United States)

    Song, Meehae; Gromala, Diane; Shaw, Chris; Barnes, Steven J.

    2010-01-01

    The research program aims to explore and examine the fine balance necessary for maintaining the interplays between technology and the immersant, including identifying qualities that contribute to creating and maintaining a sense of "presence" and "immersion" in an immersive virtual reality (IVR) experience. Building upon and extending previous work, we compare sitting meditation with walking meditation in a virtual environment (VE). The Virtual Meditative Walk, a new work-in-progress, integrates VR and biofeedback technologies with a self-directed, uni-directional treadmill. As immersants learn how to meditate while walking, robust, real-time biofeedback technology continuously measures breathing, skin conductance and heart rate. The physiological states of the immersant will in turn affect the audio and stereoscopic visual media through shutter glasses. We plan to test the potential benefits and limitations of this physically active form of meditation with data from a sitting form of meditation. A mixed-methods approach to testing user outcomes parallels the knowledge bases of the collaborative team: a physician, computer scientists and artists.

  18. The local impacts of oil palm expansion in Malaysia; An assessment based on a case study in Sabah State

    OpenAIRE

    Dayang Norwana, A.A.B.; Kanjappan, R.; Chin, M.; Schoneveld, G.C.; Potter, L; Andriani, R.

    2011-01-01

    This study is part of a broader research process assessing the local economic, social and environmental impacts from feedstock expansion for the growing biofuel sector (see German et al. 2011). Nonetheless, in the Malaysian context, biofuel production volumes are negligible despite government interest in promoting sector expansion. Since Malaysia is the second largest palm oil producer in the world, palm oil is slated to become the primary feedstock for biofuel production in the country. Sinc...

  19. Error and misconception: Relation of fraction and part-wholeHata ve kavram yanılgısı: Kesir ve parça bütün ilişkisi

    Directory of Open Access Journals (Sweden)

    Kemal Altıparmak

    2015-12-01

    Full Text Available In this study, students’ fraction concept has been studied to reveal their errors and misconceptions. For this purpose, researchers prepared an “error and misconception diagnostic test” which consists of 34 questions about part-whole relationship (simple and compound fractions, number line, and comment. The reliability coefficient of this test is 0.86. The misconceptions diagnostic test was applied to 73 secondary school students and 113 university students. According to results, students participated in the study had five different misconceptions type about fractions. They are: Unequal partitioning misconceptions; misconceptions about the expansion and simplification of fractions; misconceptions resulting from conceiving number line in part-whole relationship; misconceptions because of using unequal parts of a whole while adding; misconceptions about adding numerators and denominators of fractions.   Özet Bu çalışmada öğrencilerin kesir konusundaki hata ve kavram yanılgıları ortaya çıkarılmaya çalışılmıştır. Bu amaçla 37 soruluk “hata ve kavram yanılgıları teşhis testi” hazırlanmıştır. Bu test kesir konusu için parça-bütün, sayı doğrusu, yorum kısmından oluşmaktadır. Bu testin güvenilirlik katsayısı 0.86 bulunmuştur. Hata ve kavram yanılgıları teşhis testi 73 ortaokul, 113 üniversite öğrencisine uygulanmıştır. Sonuçlara göre, öğrenciler 5 tipte kavram hatasına sahiptirler. Bunlar sırasıyla; bir bütünün eş olmayan parçalara ayrılması ile ilgili kavram hatası, Parça bütün üzerinde genişletme ve sadeleştirme konusunda kavram yanılgısı, Sayı doğrusunu parça bütün olarak görme konusundaki kavram yanılgısı, Toplama işlemi için eş olmayan bütünlerin kullanılması üzerine kavram yanılgısı, Paydası eşit olmayan kesirlerde toplama yapılırken paylar toplanıp paya, paydalar toplanıp paydaya yazılan kavram hatasıdır.

  20. Intrauterin Beslenme Durumunun Değerlendirilmesinde Fetal ve Neonatal Antropometrik Ölçümler ve Skinfold Kalınlıkları

    OpenAIRE

    Tunç, Bahattin; Kaya, Hakan; Çalışkan, Sadettin; Öztan, Mediha

    2009-01-01

    Intrauterin Beslenme Durumunun Değerlendirilmesinde Fetal ve Neonatal Antropometrik Ölçümler ve Skinfold Kalınlıkları Bahattin Tunç, Hakan Kaya, Sadettin Çalışkan Mediha Öztan Özet Sağlıklı 29 gebenin normal vajinal yolla dünyaya gelen 29 yenidoğan bebeğinde fetal ve neonatal antropometrik ölçümler yapıldı. Antropometrik değerler neonatal skinfold kalınlıkları ile karşılaştırıldı. Anne skinfold kalınlıkları ile bebeğin skinfold kalınlıkları arasında bir korelasyon yoktu. Beb...

  1. Changes of pituitary gland volume in Kennedy disease.

    Science.gov (United States)

    Pieper, C C; Teismann, I K; Konrad, C; Heindel, W L; Schiffbauer, H

    2013-12-01

    Kennedy disease is a rare X-linked neurodegenerative disorder caused by a CAG repeat expansion in the first exon of the androgen-receptor gene. Apart from neurologic signs, this mutation can cause a partial androgen insensitivity syndrome with typical alterations of gonadotropic hormones produced by the pituitary gland. The aim of the present study was therefore to evaluate the impact of Kennedy disease on pituitary gland volume under the hypothesis that endocrinologic changes caused by partial androgen insensitivity may lead to morphologic changes (ie, hypertrophy) of the pituitary gland. Pituitary gland volume was measured in sagittal sections of 3D T1-weighted 3T-MR imaging data of 8 patients with genetically proven Kennedy disease and compared with 16 healthy age-matched control subjects by use of Multitracer by a blinded, experienced radiologist. The results were analyzed by a univariant ANOVA with total brain volume as a covariant. Furthermore, correlation and linear regression analyses were performed for pituitary volume, patient age, disease duration, and CAG repeat expansion length. Intraobserver reliability was evaluated by means of the Pearson correlation coefficient. Pituitary volume was significantly larger in patients with Kennedy disease (636 [±90] mm(3)) than in healthy control subjects (534 [±91] mm(3)) (P = .041). There was no significant difference in total brain volume (P = .379). Control subjects showed a significant decrease in volume with age (r = -0.712, P = .002), whereas there was a trend to increasing gland volume in patients with Kennedy disease (r = 0.443, P = .272). Gland volume correlated with CAG repeat expansion length in patients (r = 0.630, P = .047). The correlation coefficient for intraobserver reliability was 0.94 (P pituitary volume that correlated with the CAG repeat expansion length. This could reflect hypertrophy as the result of elevated gonadotropic hormone secretion caused by the androgen receptor mutation with partial

  2. Expansion Techniques for Collisionless Stellar Dynamical Simulations

    CERN Document Server

    Meiron, Yohai; Holley-Bockelmann, Kelly; Spurzem, Rainer

    2014-01-01

    We present GPU implementations of two fast force calculation methods, based on series expansions of the Poisson equation. One is the Self-Consistent Field (SCF) method, which is a Fourier-like expansion of the density field in some basis set; the other is the Multipole Expansion (MEX) method, which is a Taylor-like expansion of the Green's function. MEX, which has been advocated in the past, has not gained as much popularity as SCF. Both are particle-field method and optimized for collisionless galactic dynamics, but while SCF is a "pure" expansion, MEX is an expansion in just the angular part; it is thus capable of capturing radial structure easily, where SCF needs a large number of radial terms. We show that despite the expansion bias, these methods are more accurate than direct techniques for the same number of particles. The performance of our GPU code, which we call ETICS, is profiled and compared to a CPU implementation. On the tested GPU hardware, a full force calculation for one million particles took...

  3. Behaviour of Silicate Melts in Respect of Volume

    Institute of Scientific and Technical Information of China (English)

    张金民; 叶大年

    1989-01-01

    The volumes per oxygen of some silicate melts have been calculated and then compared with those of silicate glasses.It is suggested that the volume of a silicate melt can be divided into two parts.One is contri buted by the silicon-oxygen network and the other by the “oxides”.Variation patterns of VPOs suggest that the volume of the Si-O network generally remains unchanged and the expansion of the melt is caused mainly by the locat expansion of the “oxides”.It is further proposed that the radius of O2- shows little variation,in striking contrast to the radius of cations.The mechanism governing the expansion is discussed in detail.

  4. Free volume dilatation in polymers by ortho-positronium

    DEFF Research Database (Denmark)

    Winberg, P.; Eldrup, Morten Mostgaard; Maurer, F.H.J.

    2012-01-01

    The possibility of positronium induced free volume cavity expansion in some polymers above the glass transition temperature was investigated using experimental positron annihilation lifetime data from the literature for polydimethylsiloxane, polyisobutylene, and polybutadiene as function of tempe......The possibility of positronium induced free volume cavity expansion in some polymers above the glass transition temperature was investigated using experimental positron annihilation lifetime data from the literature for polydimethylsiloxane, polyisobutylene, and polybutadiene as function...... of temperature. The results suggest that free volume sites can expand towards an equilibrium size, determined as the equilibrium Ps-bubble size defined earlier for low-molecular-weight liquids. The expansion can be explained by the increase of molecular mobility and hence decrease of relaxation times, which...

  5. The expansion of a plasma into a vacuum - Basic phenomena and processes and applications to space plasma physics

    Science.gov (United States)

    Wright, K. H., Jr.; Stone, N. H.; Samir, U.

    1983-01-01

    In this review attention is called to basic phenomena and physical processes involved in the expansion of a plasma into a vacuum, or the expansion of a plasma into a more tenuous plasma, in particular the fact that upon the expansion, ions are accelerated and reach energies well above their thermal energy. Also, in the process of the expansion a rarefaction wave propagates into the ambient plasma, an ion front moves into the expansion volume, and discontinuities in plasma parameters occur. The physical processes which cause the above phenomena are discussed, and their possible application is suggested for the case of the distribution of ions and electrons (hence plasma potential and electric fields) in the wake region behind artificial and natural obstacles moving supersonically in a rarefied space plasma. To illustrate this, some in situ results are reexamined. Directions for future work in this area via the utilization of the Space Shuttle and laboratory work are also mentioned.

  6. Giant negative thermal expansion in magnetic nanocrystals.

    Science.gov (United States)

    Zheng, X G; Kubozono, H; Yamada, H; Kato, K; Ishiwata, Y; Xu, C N

    2008-12-01

    Most solids expand when they are heated, but a property known as negative thermal expansion has been observed in a number of materials, including the oxide ZrW2O8 (ref. 1) and the framework material ZnxCd1-x(CN)2 (refs 2,3). This unusual behaviour can be understood in terms of low-energy phonons, while the colossal values of both positive and negative thermal expansion recently observed in another framework material, Ag3[Co(CN)6], have been explained in terms of the geometric flexibility of its metal-cyanide-metal linkages. Thermal expansion can also be stopped in some magnetic transition metal alloys below their magnetic ordering temperature, a phenomenon known as the Invar effect, and the possibility of exploiting materials with tuneable positive or negative thermal expansion in industrial applications has led to intense interest in both the Invar effect and negative thermal expansion. Here we report the results of thermal expansion experiments on three magnetic nanocrystals-CuO, MnF2 and NiO-and find evidence for negative thermal expansion in both CuO and MnF2 below their magnetic ordering temperatures, but not in NiO. Larger particles of CuO and MnF2 also show prominent magnetostriction (that is, they change shape in response to an applied magnetic field), which results in significantly reduced thermal expansion below their magnetic ordering temperatures; this behaviour is not observed in NiO. We propose that the negative thermal expansion effect in CuO (which is four times larger than that observed in ZrW2O8) and MnF2 is a general property of nanoparticles in which there is strong coupling between magnetism and the crystal lattice.

  7. Proceedings of the XXII A.I.VE.LA. National Meeting

    Science.gov (United States)

    Primo Tomasini, Enrico

    2015-11-01

    A.I.VE.LA. - the Italian Association of Laser Velocimetry and non-invasive diagnostics - is a non-profit cultural association whose objective is to promote and support research in the field of non-contact or minimally invasive measurement techniques, particularly electromagnetic-based techniques and optical techniques. Through its Annual Meeting, AIVELA aims to create an active and stimulating forum where current research results and technical advances can be exchanged and the development of new systems for laboratory use, field testing and industrial application can be promoted. The techniques covered include Laser Doppler Anemometry - LDA, Phase Doppler Anemometry - PDA, Image Velocimetry - PIV, Flow visualization techniques, Spectroscopic measurement techniques (LIF, Raman, etc.), Laser Doppler Vibrometry - LDV, Speckle Pattern Interferometry - ESPI, Holographic techniques, Shearography, Digital Image Correlation - DIC, Moiré techniques, Structured light techniques, Infrared imaging, Photoelasticity, Image based measurement techniques, Ultrasonic sensing, Acoustic and Aeroacoustic measurements, etc. The first Annual Meeting was held back in October 1992 and since then there has been a large consensus among the research and scientific communities that the papers presented at the event are of a high scientific interest. The XXII AIVELA Annual Meeting was held at the Faculty of Engineering of University of Rome Tor Vergata on 15-16 December 2014 and was organised in collaboration with the International Master Courses in "Protection Against CBRNe Events". This volume contains a selection of the papers presented at the event. The detailed Programme of the Meeting can be found at: http://www.aivela.org/XXII_Convegno/index.html Trusting our Association and its initiatives will meet your interest, I wish to thank you in advance for your kind attention and hope to meet you soon at one of our events.

  8. Volume conjecture for $SU(n)$-invariants

    CERN Document Server

    Chen, Qingtao; Zhu, Shengmao

    2015-01-01

    This paper discuss an intrinsic relation among congruent relations \\cite{CLPZ}, cyclotomic expansion and Volume Conjecture for $SU(n)$ invariants. Motivated by the congruent relations for $SU(n)$ invariants obtained in our previous work \\cite{CLPZ}, we study certain limits of the $SU(n)$ invariants at various roots of unit. First, we prove a new symmetry property for the $SU(n)$ invariants by using a symmetry of colored HOMFLYPT invariants. Then we propose some conjectural formulas including the cyclotomic expansion conjecture and volume conjecture for $SU(n)$ invariants (specialization of colored HOMFLYPT invariants). We also give the proofs of these conjectural formulas for the case of figure-eight knot.

  9. HIV DNA in CD14+ Reservoirs is Associated with Regional Brain Atrophy in cART-Naïve Patients

    Science.gov (United States)

    Kallianpur, Kalpana J.; Valcour, Victor G.; Lerdlum, Sukalaya; Busovaca, Edgar; Agsalda, Melissa; Sithinamsuwan, Pasiri; Chalermchai, Thep; Fletcher, James L.K.; Tipsuk, Somporn; Shikuma, Cecilia M.; Shiramizu, Bruce T.; Ananworanich, Jintanat

    2014-01-01

    Objective To examine associations between regional brain volumes and HIV DNA in peripheral CD14+ cells (monocytes) among HIV-infected individuals naïve to combination antiretroviral therapy (cART). Design A prospective study of HIV-infected Thai individuals who met Thai national criteria for cART initiation. Enrollment was stratified by HIV DNA in a blinded fashion. Methods CD14+ cells were isolated from peripheral mononuclear cells to high purity (median 91.4% monocytes by flow cytometry), and HIV DNA was quantified by multiplex real-time PCR. Baseline regional brain volumes obtained by T1-weighted 1.5-Tesla magnetic resonance imaging were compared between HIV DNA groups using analysis of covariance (ANCOVA). Results We studied 60 subjects with mean (SD) age of 34.7 (7.0) years, CD4 T-lymphocyte count of 232 (137) cells/mm3, and log10 plasma HIV RNA of 4.8 (0.73). Median (IQR) HIV DNA copy number per 106 CD14+ cells was 54 (102). Using our previously determined optimal cut-point of 45 copies/106 cells for this cohort, a threshold value above which CD14+ HIV DNA identified HIV-associated neurocognitive disorders (HAND), we found that CD14+ HIV DNA ≥ 45 copies/106 cells was associated with reduced volumes of the nucleus accumbens (p = 0.021), brainstem (p = 0.033) and total gray matter (p = 0.045) independently of age, CD4 count and intracranial volume. Conclusion HIV DNA burden in CD14+ monocytes is directly linked to brain volumetric loss. Our findings implicate peripheral viral reservoirs in HIV-associated brain atrophy and support their involvement in the neuropathogenesis of HAND, underscoring the need for therapies that target these cells. PMID:25232899

  10. Critical exponents from large mass expansion

    CERN Document Server

    Yamada, Hirofumi

    2014-01-01

    We perform estimation of critical exponents via large mass expansion under crucial help of delta-expansion. We address to the three dimensional Ising model at high temperature and estimate omega, the correction-to-scaling exponent, nu, eta and gamma in unbiased and self-contained manner. The results read at the highest 25th order expansion omega=0.8002, nu=0.6295, eta=0.0369 and gamma=1.2357. Estimation biased by omega=0.84(4) is also performed and proved to be in agreement with the summary of recent literatures.

  11. ON CONVERGENCE OF WAVELET PACKET EXPANSIONS

    Institute of Scientific and Technical Information of China (English)

    Morten Nielsen

    2002-01-01

    It is well known that the-Walsh-Fourier expansion of a function from the block space ([0, 1 ) ), 1 <q≤∞, converges pointwise a.e. We prove that the same result is true for the expansion of a function from in certain periodixed smooth periodic non-stationary wavelet packets bases based on the Haar filters. We also consider wavelet packets based on the Shannon filters and show that the expansion of Lp-functions, 1<p<∞, converges in norm and pointwise almost everywhere.

  12. Extrudate Expansion Modelling through Dimensional Analysis Method

    DEFF Research Database (Denmark)

    A new model framework is proposed to correlate extrudate expansion and extrusion operation parameters for a food extrusion cooking process through dimensional analysis principle, i.e. Buckingham pi theorem. Three dimensionless groups, i.e. energy, water content and temperature, are suggested...... to describe the extrudates expansion. From the three dimensionless groups, an equation with three experimentally determined parameters is derived to express the extrudate expansion. The model is evaluated with whole wheat flour and aquatic feed extrusion experimental data. The average deviations...

  13. Does cosmological expansion affect local physics?

    CERN Document Server

    Giulini, Domenico

    2013-01-01

    In this contribution I wish to address the question whether, and how, the global cosmological expansion influences local physics. I argue that a pseudo Newtonian picture can be quite accurate if ``expansion'' is taken to be an attribute of the inertial structure rather than of ``space'' in some substantivalist sense. This contradicts the often-heard suggestion to imagine cosmological expansion as that of ``space itself''. Regarding General Relativity, I emphasise the need for proper geometric characterisations in order to meaningfully compare localised systems in different spacetimes, like black holes in static and expanding environments. Examples of this sort are discussed in some detail to clearly map out the problems.

  14. Some Improved Nonperturbative Bounds for Fermionic Expansions

    Energy Technology Data Exchange (ETDEWEB)

    Lohmann, Martin, E-mail: marlohmann@gmail.com [Universita di Roma Tre, Dipartimento di Matematica (Italy)

    2016-06-15

    We reconsider the Gram-Hadamard bound as it is used in constructive quantum field theory and many body physics to prove convergence of Fermionic perturbative expansions. Our approach uses a recursion for the amplitudes of the expansion, discovered in a model problem by Djokic (2013). It explains the standard way to bound the expansion from a new point of view, and for some of the amplitudes provides new bounds, which avoid the use of Fourier transform, and are therefore superior to the standard bounds for models like the cold interacting Fermi gas.

  15. Hubble expansion is not a velocity

    Science.gov (United States)

    Ma, Yin-Zhe; Zhang, Shuang-Nan

    2016-11-01

    In this paper, we clarify the difference between the Hubble expansion and the Doppler shift pedagogically and illustrate both physically and mathematically why the Hubble expansion cannot be regarded as a velocity. Therefore, we suggest to replace the misleading word ‘recession velocity’ to be ‘Hubble recession’ to describe the cosmic expansion. We further derive how the peculiar velocity of a galaxy is related to its observed redshift and proper distance, which has practical use in the galaxy redshift and distance surveys.

  16. Fear reactions to snakes in naïve mouse lemurs and pig-tailed macaques.

    Science.gov (United States)

    Weiss, Lucie; Brandl, Pavel; Frynta, Daniel

    2015-07-01

    Primates have been predated on by snakes throughout their evolution and as a result, antipredator responses accompanied by signs of fear are often witnessed in the wild. In captivity, however, the fear of snakes is less clear, as experiments with naïve nonhuman primates have given inconsistent results. In this study, we present evidence that naïve mouse lemurs (Microcebus murinus) and putatively naïve pig-tailed macaques (Macaca nemestrina) do exhibit fear of snakes, even though the apparent reactions are mild. In an experiment with control- or snake-odoured boxes, mouse lemurs clearly avoided feeding in the latter. When the latency of touching rubber models was measured, pig-tailed macaques took longer to touch a toy snake compared with a toy lizard. Our findings that fear of snakes is shown by naïve individuals support the hypothesis that it is innate in primates.

  17. Lipoprotein Metabolizması ve Ateroskleroz ile İlişkisi

    OpenAIRE

    Delibaş, Namık; Tahan, Veysel

    2009-01-01

    SüleymanDemirel Üniversitesi TIP FAKÜLTESİ DERGİSİ: 1995 Haziran; 2(2) Lipoprotein Metabolizması ve Ateroskleroz ile İlişkisi Namık Delibaş Veysel Tahan Özet Anormal lipoprotein düzeyleri ateroskleroz risk faktörleri arasındadır ve koroner arter hastalıklarının değerlendirilmesinde biyokimyasal bir markerdir. Apolipo-proteinler lipoproteinlerin sentez ve katabolizmasında önemli rol oynar. Apo A-I, lesitin kolesterol acil transferazı aktive eder. Apo C-II ve C-lIl ...

  18. Thermal Expansion and Diffusion Coefficients of Carbon Nanotube-Polymer Composites

    Science.gov (United States)

    Wei, Chengyu; Srivastava, Deepak; Cho, Kyeongjae; Biegel, Bryan (Technical Monitor)

    2001-01-01

    Classical molecular dynamics (MD) simulations employing Brenner potential for intra-nanotube interactions and van der Waals forces for polymer-nanotube interface have been used to investigate thermal expansion and diffusion characteristics of carbon nanotube-polyethylene composites. Addition of carbon nanotubes to polymer matrix is found to significantly increase the glass transition temperature Tg, and thermal expansion and diffusion coefficients in the composite above Tg. The increase has been attributed to the temperature dependent increase of the excluded volume for the polymer chains, and the findings could have implications in the composite processing, coating and painting applications.

  19. The effect of water on the thermal expansion behavior of FM5055 carbon phenolic

    Science.gov (United States)

    Sullivan, Roy M.

    1995-01-01

    The effect of water on the thermal expansion behavior of FM5055 carbon phenolic is studied using a theory of mixtures approach. A partial pressure expression for the water constituent was obtained based upon certain assumptions regarding the thermodynamic state of water as it resides in the free volumes of the polymer. A simple constitutive model is used to simulate the polymer strain due to the application of the partial pressure of water. The resulting theory is applied to model the effect of moisture on the thermal expansion of FM5055 carbon phenolic specimens. The application of the theory results in calculated strains which were in close agreement with the measured strains.

  20. BİLGİSAY AR AGLARI VE GÜVENLİK

    Directory of Open Access Journals (Sweden)

    Cüneyt Bergel

    2005-01-01

    Full Text Available Bu tezde, bilgisayar ağlarının temelleri (verihaberleşme sistemleri, referans modelleri, TCPIIPprotokol grubu, Lan ve Wan teknolojilerihakkında bilgiler verilmiş ve bilgisayar ağlarındagüvenliğin nasıl sağlanması gerektiği anlatılmıştır.

  1. Micro-Trottoir à Genève à propos du CERN et du LHC

    CERN Multimedia

    CERN Video Productions

    2009-01-01

    Questions : Qu'est-ce-que le LHC? Quelle est la fonction du LHC? Qu'est-ce-que le CERN? D'après vous, les recherches engendrées pour le LHC peuvent-elles ?tre bénéfiques, utiles pour la société? Où a été inventé le Web? Lieux : Forum Meyrin Université de Genève Genève Centre

  2. Linear stability analysis of axisymmetric flow over a sudden expansion in an annular pipe

    Science.gov (United States)

    Beladi, Behnaz; Kuhlmann, Hendrik Christoph

    2016-11-01

    A global temporal linear stability analysis is performed of the fully-developed axisymmetric incompressible Newtonian flow in an annular pipe with a sudden radially-inward expansion. The geometry is characterized by the radial expansion ratio (radial step height to the outlet gap width) and the outlet radius ratio (inner-to-outer radius). Stability boundaries have been calculated with finite volumes for an outlet radius ratio of 0 . 1 and expansion ratios from 0 . 25 to 0 . 75 . For expansion ratios less than 0 . 55 the most dangerous mode has an azimuthal wave number m = 3 , whereas m = 2 for larger expansion ratios. An a posteriori analysis of the kinetic energy transferred between the basic state and the critical mode allows to check the energy conservation and to identify the physical instability mechanism. For all expansion ratios considered the basic flow arises as an annular jet between two separation zones which are located immediately after the step. The jet gradually widens downstream before reattaching to the cylinders. The deceleration of the flow associated with the widening of the jet is found to be the primary source of energy for the critical modes.

  3. Investigation of Key Parameters of Rock Cracking Using the Expansion of Vermiculite Materia

    Directory of Open Access Journals (Sweden)

    Chi-Hyung Ahn

    2015-10-01

    Full Text Available The demand for the development of underground spaces has been sharply increased in lieu of saturated ground spaces because the residents of cities have steadily increased since the 1980s. The traditional widely used excavation methods (i.e., explosion and shield have caused many problems, such as noise, vibration, extended schedule, and increased costs. The vibration-free (and explosion-free excavation method has currently attracted attention in the construction site because of the advantage of definitively solving these issues. For such reason, a new excavation method that utilizes the expansion of vermiculite with relatively fewer defects is proposed in this study. In general, vermiculite materials are rapidly expanded in volume when they receive thermal energy. Expansion pressure can be produced by thermal expansion of vermiculite in a steel tube, and measured by laboratory tests. The experimental tests are performed with various influencing parameters in an effort to seek the optimal condition to effectively increase expansion pressure at the same temperature. Then, calibrated expansion pressure is estimated, and compared to each model. After analyzing test results for expansion pressure, it is verified that vermiculite expanded by heat can provide enough internal pressure to break hard rock during tunneling work.

  4. Investigation of Key Parameters of Rock Cracking Using the Expansion of Vermiculite Materials

    Science.gov (United States)

    Ahn, Chi-Hyung; Hu, Jong Wan

    2015-01-01

    The demand for the development of underground spaces has been sharply increased in lieu of saturated ground spaces because the residents of cities have steadily increased since the 1980s. The traditional widely used excavation methods (i.e., explosion and shield) have caused many problems, such as noise, vibration, extended schedule, and increased costs. The vibration-free (and explosion-free) excavation method has currently attracted attention in the construction site because of the advantage of definitively solving these issues. For such reason, a new excavation method that utilizes the expansion of vermiculite with relatively fewer defects is proposed in this study. In general, vermiculite materials are rapidly expanded in volume when they receive thermal energy. Expansion pressure can be produced by thermal expansion of vermiculite in a steel tube, and measured by laboratory tests. The experimental tests are performed with various influencing parameters in an effort to seek the optimal condition to effectively increase expansion pressure at the same temperature. Then, calibrated expansion pressure is estimated, and compared to each model. After analyzing test results for expansion pressure, it is verified that vermiculite expanded by heat can provide enough internal pressure to break hard rock during tunneling work. PMID:28793610

  5. Rab5-mediated VE-cadherin internalization regulates the barrier function of the lung microvascular endothelium.

    Science.gov (United States)

    Yang, Junjun; Yao, Wei; Qian, Guisheng; Wei, Zhenghua; Wu, Guangyu; Wang, Guansong

    2015-12-01

    The small GTPase Rab5 has been well defined to control the vesicle-mediated plasma membrane protein transport to the endosomal compartment. However, its function in the internalization of vascular endothelial (VE)-cadherin, an important component of adherens junctions, and as a result regulating the endothelial cell polarity and barrier function remain unknown. Here, we demonstrated that lipopolysaccharide (LPS) simulation markedly enhanced the activation and expression of Rab5 in human pulmonary microvascular endothelial cells (HPMECs), which is accompanied by VE-cadherin internalization. In parallel, LPS challenge also induced abnormal cell polarity and dysfunction of the endothelial barrier in HPMECs. LPS stimulation promoted the translocation of VE-cadherin from the plasma membrane to intracellular compartments, and intracellularly expressed VE-cadherin was extensively colocalized with Rab5. Small interfering RNA (siRNA)-mediated depletion of Rab5a expression attenuated the disruption of LPS-induced internalization of VE-cadherin and the disorder of cell polarity. Furthermore, knockdown of Rab5 inhibited the vascular endothelial hyperpermeability and protected endothelial barrier function from LPS injury, both in vitro and in vivo. These results suggest that Rab5 is a critical mediator of LPS-induced endothelial barrier dysfunction, which is likely mediated through regulating VE-cadherin internalization. These findings provide evidence, implicating that Rab5a is a potential therapeutic target for preventing endothelial barrier disruption and vascular inflammation.

  6. Slow Learner Prediction using Multi-Variate Naïve Bayes Classification Algorithm

    Directory of Open Access Journals (Sweden)

    Shiwani Rana

    2016-12-01

    Full Text Available Machine Learning is a field of computer science that learns from data by studying algorithms and their constructions. In machine learning, for specific inputs, algorithms help to make predictions. Classification is a supervised learning approach, which maps a data item into predefined classes. For predicting slow learners in an institute, a modified Naïve Bayes algorithm implemented. The implementation is carried sing Python.  It takes into account a combination of likewise multi-valued attributes. A dataset of the 60 students of BE (Information Technology Third Semester for the subject of Digital Electronics of University Institute of Engineering and Technology (UIET, Panjab University (PU, Chandigarh, India is taken to carry out the simulations. The analysis is done by choosing most significant forty-eight attributes. The experimental results have shown that the modified Naïve Bayes model has outperformed the Naïve Bayes Classifier in accuracy but requires significant improvement in the terms of elapsed time. By using Modified Naïve Bayes approach, the accuracy is found out to be 71.66% whereas it is calculated 66.66% using existing Naïve Bayes model. Further, a comparison is drawn by using WEKA tool. Here, an accuracy of Naïve Bayes is obtained as 58.33 %.

  7. İnsani yardım ve lojistik yönetimi

    Directory of Open Access Journals (Sweden)

    Berna Çağlar

    2013-01-01

    Full Text Available İnsanların ve toplumların başa çıkmakta zorlandığı ya da başa çıkamadıkları, çevreyi olumsuz etkileyen olağanüstü durumlara afet denilmektedir. İnsani yardım lojistiği; acil durum ve afetlerden etkilenmiş ihtiyaç sahiplerine yardım etmek üzere gerekli malzeme, bilgi ve hizmetlerle ilgili lojistik faaliyetlerin etkin ve verimli bir şekilde yönetimidir. Bu çalışmada ilk bölümde; afet yönetimi kavramı üzerinde durulmuştur. Bu kavramla ilişkili insani yardım lojistiği tanımlarına, işlevleri ve süreçlerine yer verilmiştir. Bir sonraki bölümde; etkin insani yardım lojistiği faaliyetleri için işletmelerin sahip olması gereken yeteneklerden ve performans yönetiminden bahsedilmiştir. Sonuç bölümünde ise; insani yardım lojistiği konusunda genel bir derlemeye gidilmiştir.

  8. İLAÇ ENDÜSTRİSİNDE UZMAN SİSTE MLER VE UYGULAMALARI

    Directory of Open Access Journals (Sweden)

    TUBA CANVAR

    2002-06-01

    Full Text Available Insan zekasını ve becerisini her alanda yakalama isteği araştırmaları bu alana yoğunlaştırmıştır. Günümüzde, Yapay Zeka yöntemleri ile çözülmüş bir çok gerçek dünya problemi ve Yapay Zeka' nın bir çok ticari uygulaması vardır. Bu çalışmada, Yapay Zeka' nın en yaygın dalı, Uzman Sistem' ler ve tıp ile farmasotikte uygulamalarından bahsedilmiştir. B una ilave olarak, farmasotik prosesler için Delphi 'de geliştirilmiş basit ve küçük bir Uzman Sistemin tasarımı ve bilgisayar programı da anlatılmıştır. Bu çalışmanın amacı Uzman Sistem' lere dikkati çekmek ve bu metodu kuJianarak farmasotik proseslerin verimliliğini arttırma olasılığını göstermektir.

  9. Tüketim, Nüfus Ve Çevre Sorunları: Orantısız Denklem / Consumption, Population And Environment Problems: Disproportionate Equation

    Directory of Open Access Journals (Sweden)

    Recep Ardoğan

    2012-12-01

    Full Text Available Çevre sorunlarının temel nedenlerinden biri de artan tüketim ve israftır. tüketim, günümüzde israf kavramınının dışında tutulur hale gelmiş, sosyalleşmenin, mutluluğun göstergesi olarak görülmeye başlamıştır. İsrafın temel nedenleri arasında tüketimin bir yaşam biçimi olarak görülmesi, ben merkezci yaklaşım, mülkiyetin mutlaklaştırılması başta gelmektedir. bunun yanında çevre sorunlarının nedenleri arasında gelişmemiş ülkelerdeki nüfusun gösterilmesi dikkat çekmektedir. Çünkü nüfus oranının az olduğu bazı ülkelerdeki tüketim, soruna neden olarak gösterilen nüfusun tüketiminden kat kat fazladır. İslam’ın teshir ve emanet anlayışı da israf ve lüks (gösteriş ve prestij amaçlı tüketimi reddeder. İsraf ve lüksün yasaklanması da çevre sorunlarının temel bir nedenini önlemektedir. Consumption, Population And Environment Problems: Disproportionate Equation Environment problems that are increased recently necessitate studying relation between human and nature. In this issue, the illustrating of the present population and population growth as a major factor of environment problems is a misconception. Whereas, consumption of minority group of the world has been exceeding multiplex the volume of the consumption of others people. This study examines the consumption inequalities between different social strata.

  10. Surgically assisted rapid maxillary expansion in adults.

    Science.gov (United States)

    Pogrel, M A; Kaban, L B; Vargervik, K; Baumrind, S

    1992-01-01

    Twelve adults with maxillary width discrepancy of greater than 5 mm were treated by surgically assisted rapid maxillary expansion. The procedure consisted of bilateral zygomatic buttress and midpalatal osteotomies combined with the use of a tooth-borne orthopedic device postoperatively. Mean palatal expansion of 7.5 mm (range of 6 to 13 mm), measured in the first molar region, was achieved within 3 weeks in all patients. Expansion remained stable during the 12-month study period, with a mean relapse for the entire group of 0.88 +/- 0.48 mm. Morbidity was limited to mild postoperative discomfort. The results of this preliminary study indicated that surgically assisted rapid maxillary expansion is a safe, simple, and reliable procedure for achieving a permanent increase in skeletal maxillary width in adults. Further study is necessary to document the three-dimensional movements of the maxillary segments and long-term stability of the skeletal and dental changes.

  11. High Falls generation station expansion approvals process

    Energy Technology Data Exchange (ETDEWEB)

    Litschko, C. [Lakeland Holding, Bracebridge, ON (Canada)

    2005-07-01

    Lakeland Holding Ltd. is the parent company for Lakeland Power Distribution Ltd., Bracebridge Generation Ltd., and Lakeland Energy Ltd. This PowerPoint presentation highlighted the High Falls generation expansion process. During construction of the High Falls plant, a concrete foundation was built beside the plant for future expansion. The expansion process involves building a 1,500 kilowatt generator to supply electricity to as many as 1600 households. The presentation described the context and background for the expansion and presented information on the water power generation plants. It presented site specifications as well as the approvals process by which final approval was granted in 2004. Observations and lessons learned from the approval process were identified. figs.

  12. An effective theory of accelerated expansion

    CERN Document Server

    Jimenez, Raul; Verde, Licia

    2011-01-01

    We work out an effective theory of accelerated expansion to describe general phenomena of inflation and acceleration (dark energy) in the Universe. Our aim is to determine from theoretical grounds, in a physically-motivated and model independent way, which and how many (free) parameters are needed to broadly capture the physics of a theory describing cosmic acceleration. Our goal is to make as much as possible transparent the physical interpretation of the parameters describing the expansion. We show that, at leading order, there are five independent parameters, of which one can be constrained via general relativity tests. The other four parameters need to be determined by observing and measuring the cosmic expansion rate only, H(z). Therefore we suggest that future cosmology surveys focus on obtaining an accurate as possible measurement of $H(z)$ to constrain the nature of accelerated expansion (dark energy and/or inflation).

  13. Collisional and collisionless expansion of Yukawa balls.

    Science.gov (United States)

    Piel, Alexander; Goree, John A

    2013-12-01

    The expansion of Yukawa balls is studied by means of molecular dynamics simulations of collisionless and collisional situations. High computation speed was achieved by using the parallel computing power of graphics processing units. When the radius of the Yukawa ball is large compared to the shielding length, the expansion process starts with the blow-off of the outermost layer. A rarefactive wave subsequently propagates radially inward at the speed of longitudinal phonons. This mechanism is fundamentally different from Coulomb explosions, which employ a self-similar expansion of the entire system. In the collisionless limit, the outer layers carry away most of the available energy. The simulations are compared with analytical estimates. In the collisional case, the expansion process can be described by a nonlinear diffusion equation that is a special case of the porous medium equation.

  14. On Learning Ring-Sum-Expansions

    DEFF Research Database (Denmark)

    Fischer, Paul; Simon, H. -U.

    1992-01-01

    The problem of learning ring-sum-expansions from examples is studied. Ring-sum-expansions (RSE) are representations of Boolean functions over the base {#123;small infinum, (+), 1}#125;, which reflect arithmetic operations in GF(2). k-RSE is the class of ring-sum-expansions containing only monomials...... of a 2-CNF and a 1-DNF. Finally the paper presents learning (on-line prediction) algorithms for k-RSE that are optimal with respect to the sample size (worst case mistake bound)...... of length at most k:. term-RSE is the class of ring-sum-expansions having at most I: monomials. It is shown that k-RSE, k>or=1, is learnable while k-term-RSE, k>2, is not learnable if RPnot=NP. Without using a complexity-theoretical hypothesis, it is proven that k-RSE, k>or=1, and k-term-RSE, k>or=2 cannot...

  15. Postmodernism and Education / Postmodernizm ve Eğitim

    Directory of Open Access Journals (Sweden)

    Latife KIRBAŞOĞLU KILIÇ

    2014-03-01

    Full Text Available In recent years, a statement whose name we hear frequently with the criticism of modernism has attracted attention on itself: postmodernism. This statement which was brought about with the reborn process of the societies after industrialization draws a challenging perspective with its criticism and the things it promises. The postmodern attitude creating a new perspective to the terms of freedom, equality and justice has come into our lives intensively with the innovations and we can see its reflections in various fields; from art to sociology. Postmodernism has, beyond any doubt, effects on education. A new education environment in which the student is in the center of education as an individual and the teacher is a guide has been thought. The student’s constructing his own learning, presenting alternative subject based on the student’s choice by schools are considered to be the most important innovations. With the integration of postmodernism approach into education, the perception of literate people has changed. In this process which creates a new approach and with which it is seen that the trainings on the basic skills are not enough for the literate individual, the individual should have the skills to use mass media effectively. In this sense, the necessity to train individual according to his predominant skills makes it essential to question the teaching approaches. This study analyses the term of postmodernism and it relationship with education within the scope of these necessities. Son yıllarda modernizmin eleştirisiyle adını sıkça duyduğumuz bir söylem dikkatleri üzerine çekmektedir: postmodernizm. Sanayi sonrası toplumların var oluş sürecinin doğurduğu bu kavram, eleştirisi ve vadettikleriyle hayli iddialı bir perspektif çizmektedir. Özgürlük, eşitlik ve adalet kavramlarına yeni bir bakış kazandıran postmodern tavır, sanattan sosyolojiye dek yankılarını çok çeşitli alanlarda hissedebilece

  16. Fuel Thermal Expansion (FTHEXP). [BWR; PWR

    Energy Technology Data Exchange (ETDEWEB)

    Reymann, G. A.

    1978-07-01

    A model is presented which deals with dimensional changes in LWR fuel pellets caused by changes in temperature. It is capable of dealing with any combination of UO/sub 2/ and PuO/sub 2/ in solid, liquid or mixed phase states, and includes expansion due to the solid-liquid phase change. The function FTHEXP models fuel thermal expansion as a function of temperature, fraction of PuO/sub 2/, and the fraction of fuel which is molten.

  17. Thermal expansion coefficient of binary semiconductors

    Energy Technology Data Exchange (ETDEWEB)

    Kumar, V.; Sastry, B.S.R. [Indian School of Mines, Dhanbad (India). Dept. of Electronics and Instrumentation

    2001-07-01

    The linear thermal expansion coefficient of tetrahedrally coordinated A{sup II}B{sup VI} and A{sup III}B{sup V} semiconductors has been calculated using plasmon energy data. A simple relation between the bond length and plasmon energy has been derived. The calculated values of thermal expansion coefficient and bond length have been compared with the experimental values and the values reported by different workers. An excellent experiment has been obtained between them. (orig.)

  18. Index calculation by means of harmonic expansion

    CERN Document Server

    Imamura, Yosuke

    2015-01-01

    We review derivation of superconformal indices by means of supersymmetric localization and spherical harmonic expansion for 3d N=2, 4d N=1, and 6d N=(1,0) supersymmetric gauge theories. We demonstrate calculation of indices for vector multiplets in each dimensions by analysing energy eigenmodes in S^pxR. For the 6d index we consider the perturbative contribution only. We put focus on technical details of harmonic expansion rather than physical applications.

  19. Optimized $\\delta$ expansion for relativistic nuclear models

    CERN Document Server

    Krein, G I; Peres-Menezes, D; Nielsen, M; Pinto, M B

    1998-01-01

    The optimized $\\delta$-expansion is a nonperturbative approach for field theoretic models which combines the techniques of perturbation theory and the variational principle. This technique is discussed in the $\\lambda \\phi^4$ model and then implemented in the Walecka model for the equation of state of nuclear matter. The results obtained with the $\\delta$ expansion are compared with those obtained with the traditional mean field, relativistic Hartree and Hartree-Fock approximations.

  20. On storm weakening during substorm expansion phase

    Directory of Open Access Journals (Sweden)

    G. L. Siscoe

    Full Text Available Iyemori and Rao recently presented evidence that the strength of a magnetic storm, as measured by -Dst, weakens, or its rate of growth slows, during the substorm expansion phase. Yet the expansion phase is known to inject energetic particles into the ring current, which should strengthen the storm. We propose to reconcile these apparently contradictory results by combining the virial theorem and a principle of energy partitioning between energy storage elements in a system with dissipation. As applied to the unloading description of the substorm expansion phase, the virial theorem states that -Dst is proportional to the sum of the total magnetic energy and twice the total kinetic energy in the magnetosphere including the tail. Thus if expansion phase involves converting magnetic energy stored in the tail into kinetic energy stored in the ring current, a drop in -Dst during expansion phase requires that less than half the drop in magnetic energy goes into the ring current, the rest going into the ionosphere. Indeed Weiss et al., have estimated that the energy dissipated in the ionosphere during expansion phase is twice that injected into the ring current. This conclusion is also consistent with the mentioned energy partitioning principle, which requires that more energy be dissipated than transferred between storage elements. While Iyemori and Rao's observations seem to contradict the hypothesis that storms consist at least in part of a sum of substorms, this mode of description might nonetheless be preserved by including the substorm's growth-phase contribution. Then the change in storm strength measured from before the growth phase to after the expansion phase is positive, even though the expansion phase alone makes a negative contribution.

  1. Expansion of Bubbles in Inflationary Universe

    OpenAIRE

    Mohazzab, M.; Jabbari, M. M. Sheikh; Salehi, H.

    1995-01-01

    We show that particle production during the expansion of bubbles of true vacuum in the sea of false vacuum is possible and calculate the resulting rate. As a result the nucleated bubbles cannot expand due to the transfer of false vacuum energy to the created particles inside the bubbles. Therefore all the inflationary models dealing with the nucleation and expansion of the bubbles (including extended inflation) may not be viable.

  2. Expansion of bubbles in inflationary universe

    CERN Document Server

    Mohazzab, M

    1995-01-01

    We show that particle production during the expansion of bubbles of true vacuum in the sea of false vacuum is possible and calculate the resulting rate. As a result the nucleated bubbles cannot expand due to the transfer of false vacuum energy to the created particles inside the bubbles. Therefore all the inflationary models dealing with the nucleation and expansion of the bubbles (including extended inflation) may not be viable.

  3. Thermal Expansion Coefficients of Thin Crystal Films

    Institute of Scientific and Technical Information of China (English)

    2005-01-01

    The formulas for atomic displacements and Hamiltonian of a thin crystal film in phonon occupation number representation are obtained with the aid of Green's function theory. On the basis of these results, the formulas for thermal expansion coefficients of the thin crystal film are derived with the perturbation theory, and the numerical calculations are carried out. The results show that the thinner films have larger thermal expansion coefficients.

  4. Formik Asitin İn Vitro Rumen Fermentasyonu ve Metan Üretimine Etkisi

    Directory of Open Access Journals (Sweden)

    Kanber Kara

    2015-11-01

    Full Text Available Bu araştırmanın amacı, in vitro gaz üretim tekniği ile yonca kuru otunun rumen fermentesyonu ve metan üretimine formik asitin etkisini belirlemektir. Çalışmada rumen sıvısı inokulumuna 0,0 (kontrol grubu, YF0, 0,1, 0,2, 0,3, 0,4 ve 0,5 ml/L (deneme grupları, sırasıyla YF1, YF2, YF3, YF4 ve YF5 düzeylerinde formik asit (Amasil85-liquid ilavesinin yonca kuru otunun toplam gaz üretimi (TGÜ, metabolik enerji (ME, organik madde sindirimine (OMS, pH ve metan üretimine etkisi belirlenmiştir. Rumen sıvısına artan düzeylerde formik asit katılması yonca kuru otunun in vitro TGÜ, ME ve OMS’ni linear, quadratik ve kübik kontrastta, metan üretimini ise linear kontrastta (yaklaşık %17’den % 20’e kadar farklılıklar ortaya çıkarmıştır. Formik asitin çalışılan parametrelere etkisi kullanılan dozuna göre farklılık göstermiştir. Formik asitin düşük dozları (0,1 ml/L ve 0,2 ml/L in vitro TGÜ, ME ve OMS’ni önemli düzeyde azaltırken, yüksek dozu (0,5 ml/L bu parametreleri önemli oranda arttırmıştır. Öte yandan orta dozlarının (0,3 ml/L ve 0,4 ml/L yonca kuru otunun in vitro TGÜ, ME ve OMS’ne önemli bir etkisi görülmedi. Ruminal pH değeri formik asit ilavesiyle değişmemiştir. Antibakteriyel, lezzet verici ve silajda fermentasyonu arttırıcı niteliğinden dolayı güvenli bir yem katkısı olarak nitelendirilen formik asitin çalışmada kullanılan tüm dozlarının in vitro metan üretimini arttırdığı belirlenmiştir. Yüksek dozlarının yonca kuru otunun ME ve OMS’ne olumlu etkisi olsa da sera gazlarını arttıran olumsuz etkisinden dolayı yemlerde sınırlı düzeyde kullanılması gerekir. Daha sonraki in vitro ve in vivo çalışmalarda, tüm çiftlik hayvanlarının yem ham maddeleri ve rasyonlarına formik asit ilavesinin sindirim sistemi parametreleri ve küresel ısınma üzerine etkisinin araştırılması faydalı olacaktır.

  5. Fixed Point Theorems for Times Reasonable Expansive Mapping

    Directory of Open Access Journals (Sweden)

    Chen Chunfang

    2008-01-01

    Full Text Available Abstract Based on previous notions of expansive mapping, times reasonable expansive mapping is defined. The existence of fixed point for times reasonable expansive mapping is discussed and some new results are obtained.

  6. Expansive Soil Crack Depth under Cumulative Damage

    Directory of Open Access Journals (Sweden)

    Bei-xiao Shi

    2014-01-01

    Full Text Available The crack developing depth is a key problem to slope stability of the expansive soil and its project governance and the crack appears under the roles of dry-wet cycle and gradually develops. It is believed from the analysis that, because of its own cohesion, the expansive soil will have a certain amount of deformation under pulling stress but without cracks. The soil body will crack only when the deformation exceeds the ultimate tensile strain that causes cracks. And it is also believed that, due to the combined effect of various environmental factors, particularly changes of the internal water content, the inherent basic physical properties of expansive soil are weakened, and irreversible cumulative damages are eventually formed, resulting in the development of expansive soil cracks in depth. Starting from the perspective of volumetric strain that is caused by water loss, considering the influences of water loss rate and dry-wet cycle on crack developing depth, the crack developing depth calculation model which considers the water loss rate and the cumulative damages is established. Both the proposal of water loss rate and the application of cumulative damage theory to the expansive soil crack development problems try to avoid difficulties in matrix suction measurement, which will surely play a good role in promoting and improving the research of unsaturated expansive soil.

  7. Thermal expansion of doped lanthanum gallates

    Indian Academy of Sciences (India)

    K T Jacob; S Jain; V S Saji; P V K Srikanth

    2010-08-01

    Thermal expansion of several compositions of Sr and Mg-doped LaGaO3 including an -site deficient composition (La0.9Sr0.1)0.98(Ga0.8Mg0.2)O2.821 were measured in the temperature range from 298 to 1273 K. The effect of doping on thermal expansion was studied by varying the composition at one site of the perovskite structure (either or ), while keeping the composition at the other site invariant. Thermal expansion varied nonlinearly with temperature and exhibited an inflexion between 550 and 620 K, probably related to the change in crystal structure from orthorhombic to rhombohedral. The dependence of average thermal expansion coefficient (av) on the dopant concentration on either or site of the perovskite structure was found to be linear, when the composition at the other site was kept constant. Mg doping on the -site had a greater effect on the average thermal expansion coefficient than Sr doping on the -site. Cation deficiency at the -site decreases thermal expansion when compositions at both sites are held constant.

  8. Influence of baroreflex on volume elasticity of heart and aorta in the rabbit.

    Science.gov (United States)

    Wronski, T; Seeliger, E; Persson, P B; Harnath, A; Flemming, B

    2002-03-01

    Optimal ventriculoaortic coupling includes tuning of elastic properties. The ratio of effective arterial elastance and left ventricular endsystolic elastance is often taken as a measure for mechanical and energetical efficiency. The present study determined the time course of ventricular and aortic volume elasticity (VE = dp/dV) throughout a complete heartbeat. This was achieved by using changes of eigenfrequency of two catheter-transducer systems under closed chest conditions in rabbits. Short-term VE modulation was studied by a baroreflex response, as induced by pressure changes applied to the carotid sinus. Long-term changes were studied in atherosclerotic rabbits (12 wk of high-cholesterol feeding). The time course and mean values of ventricular and aortic VE were changed by the baroreflex stimulus. Cholesterol feeding diminished the response. The degree of ventriculoaortic coupling, as quantified by VE(Aorta)/VE(Ventricle) ratio, varied during a single ejection period. The large span allows either maximal energetical efficiency or maximal stroke work. Although normal rabbits adjusted their ventriculoaortic coupling during baroreflex input, the cholesterol-fed rabbits failed to do so.

  9. Effects of freezing rates and cryoprotectant on thermal expansion of articular cartilage during freezing process.

    Science.gov (United States)

    Xu, Y; Sun, H J; Lv, Y; Zou, J C; Lin, B L; Hua, T C

    2013-01-01

    The intact articular cartilage has not yet been successfully preserved at low temperature most likely due to the volume expansion from water to ice during freezing. The objective of this current study focuses on examining thermal expansion behavior of articular cartilage (AC) during freezing from 0 degree C to -100 degree C. Thermo Mechanical Analysis (TMA) was used to investigate the effects of different concentrations of dimethyl sulphoxide (DMSO) (0%, 10%, 30% and 60% v/v) and different freezing rates (1 C/min, 3 C/min and 5 C/min). The results showed that: (1) the inhomogeneous thermal expansion (or contraction) presents due to inhomogeneous water distributions in articular cartilage during freezing, which also may be the most likely reason that the matrix has been damaged in cryopreserved intact articular cartilage; (2) at the phase transition temperature range, the maximum thermal strain change value for 5C/min is approximately 1.45 times than that for 1 C/min, but the maximum thermal expansion coefficient of the later is about six times than that of the former; (3) the thermal expansion coefficient decreases with increasing cooling rate at the unfrozen temperature region, but some opposite results are obtained at the frozen temperature region; (4) the higher the DMSO concentration is, at the phase change temperature region, the smaller the thermal strain change as well as the maximum thermal expansion coefficient are, but DMSO concentration exhibits little effect on the thermal expansion coefficient at both unfrozen and frozen region. Once the DMSO concentration increasing enough, e.g. 60% v/v, the thermal strain decreases linearly and smoothly without any abrupt change due to little or no ice crystal forms (i.e. vitrification) in frozen articular cartilage. This study may improve our understanding of the thermal expansion (or contraction) behavior of cryopreserved articular cartilage and it may be useful for the future study on cryopreservation of intact

  10. Thermal expansion investigation of tourmaline-group minerals

    Science.gov (United States)

    Hovis, G.; Scott, B.; Altomare, C.; Tomaino, G.

    2012-04-01

    In recent years one aim of this laboratory has been the characterization of thermal expansion in various mineral groups with an eye toward evaluation of the extent to which chemical composition affects expansion behaviour. We have undertaken studies on various mineral series including alkali feldspar, plagioclase, Ba/K-feldspar, Rb/K feldspar, nepheline/kalsilite minerals of various excess Si contents, and F/Cl/OH apatite. We turn our attention now to the tourmaline mineral system, which is of interest because of its wide variation in chemical composition, as well as its structural complexity. We have obtained multiple chemically-characterized tourmaline specimens from the U.S. National Museum of Natural History and also from George Rossman. Six specimens have been investigated so far, including elbaite, rossmanite, uvite, buergerite, schorl, and foitite. High-temperature X-ray powder diffraction measurements have been made from room temperature to 1000 °C at 75° intervals. X-ray peak positions were corrected utilizing NIST SRM 640a silicon as an internal standard. Peaks were indexed manually based on data in the literature; unit-cell dimensions were computed utilizing the software of Holland and Redfern (1997, Mineralogical Magazine). V-T relationships are generally linear, or close to it, up to the breakdown temperatures of all specimens. Coefficients of thermal expansion have been computed as (ΔV/ΔT)*(1/V0C), where V0C is the extrapolated volume intercept at 0 °C based on the various linear V-T relationships. Among the six specimens, all except foitite give thermal expansion coefficients between 23 and 26 x 10-6 deg-1. Foitite has a flatter V-T slope and thus expands less, giving a thermal expansion coefficient of 18 x 10-6. Based on the initial data, the relative uniformity of expansion behaviour in this system implies that any volumes of mixing in this system will be essentially constant with temperature, recognizing that this conclusion is based on the

  11. Changes in circulating blood volume after infusion of hydroxyethyl starch 6% in critically ill patients

    DEFF Research Database (Denmark)

    Christensen, P; Andersson, J; Rasmussen, S E;

    2001-01-01

    The cardiovascular response to a volume challenge with hydroxyethyl starch (HES) (200/0.5) 6% depends on the relation between the volume of HES 6% infused and the expansion of the blood volume in critically ill patients. However, only relatively limited data exist on the plasma expanding effect...... of infusion of HES 6% in critically ill patients. The purpose of the study was to evaluate the variation in the expansion of the circulating blood volume (CBV) in critically ill patients after infusion of 500 ml of colloid (HES (200/0.5) 6%) using the carbon monoxide method....

  12. Evidence for post-translational processing of vascular endothelial (VE-cadherin in brain tumors: towards a candidate biomarker.

    Directory of Open Access Journals (Sweden)

    Isabelle Vilgrain

    Full Text Available Vessel abnormalities are among the most important features in malignant glioma. Vascular endothelial (VE-cadherin is of major importance for vascular integrity. Upon cytokine challenge, VE-cadherin structural modifications have been described including tyrosine phosphorylation and cleavage. The goal of this study was to examine whether these events occurred in human glioma vessels. We demonstrated that VE-cadherin is highly expressed in human glioma tissue and tyrosine phosphorylated at site Y(685, a site previously found phosphorylated upon VEGF challenge, via Src activation. In vitro experiments showed that VEGF-induced VE-cadherin phosphorylation, preceded the cleavage of its extracellular adhesive domain (sVE, 90 kDa. Interestingly, metalloproteases (MMPs secreted by glioma cell lines were responsible for sVE release. Because VEGF and MMPs are important components of tumor microenvironment, we hypothesized that VE-cadherin proteolysis might occur in human brain tumors. Analysis of glioma patient sera prior treatment confirmed the presence of sVE in bloodstream. Furthermore, sVE levels studied in a cohort of 53 glioma patients were significantly predictive of the overall survival at three years (HR 0.13 [0.04; 0.40] p ≤ 0.001, irrespective to histopathological grade of tumors. Altogether, these results suggest that VE-cadherin structural modifications should be examined as candidate biomarkers of tumor vessel abnormalities, with promising applications in oncology.

  13. Discrimination of Stem Cell Status after Subjecting Cynomolgus Monkey Pluripotent Stem Cells to Naïve Conversion

    Science.gov (United States)

    Honda, Arata; Kawano, Yoshihiro; Izu, Haruna; Choijookhuu, Narantsog; Honsho, Kimiko; Nakamura, Tomonori; Yabuta, Yukihiro; Yamamoto, Takuya; Takashima, Yasuhiro; Hirose, Michiko; Sankai, Tadashi; Hishikawa, Yoshitaka; Ogura, Atsuo; Saitou, Mitinori

    2017-01-01

    Experimental animal models have played an indispensable role in the development of human induced pluripotent stem cell (iPSC) research. The derivation of high-quality (so-called “true naïve state”) iPSCs of non-human primates enhances their application and safety for human regenerative medicine. Although several attempts have been made to convert human and non-human primate PSCs into a truly naïve state, it is unclear which evaluation methods can discriminate them as being truly naïve. Here we attempted to derive naïve cynomolgus monkey (Cm) (Macaca fascicularis) embryonic stem cells (ESCs) and iPSCs. Several characteristics of naïve Cm ESCs including colony morphology, appearance of naïve-related mRNAs and proteins, leukaemia inhibitory factor dependency, and mitochondrial respiration were confirmed. Next, we generated Cm iPSCs and converted them to a naïve state. Transcriptomic comparison of PSCs with early Cm embryos elucidated the partial achievement (termed naïve-like) of their conversion. When these were subjected to in vitro neural differentiation, enhanced differentiating capacities were observed after naïve-like conversion, but some lines exhibited heterogeneity. The difficulty of achieving contribution to chimeric mouse embryos was also demonstrated. These results suggest that Cm PSCs could ameliorate their in vitro neural differentiation potential even though they could not display true naïve characteristics. PMID:28349944

  14. İçme ve sulama sularında bor kirliliği ve bor giderme yöntemleri

    Directory of Open Access Journals (Sweden)

    Meltem Bilici Başkan

    2014-03-01

    Full Text Available Periyodik cetvelin 3A grubunda yer alan bor yüksek iyonlaşma potansiyeline sahip olması nedeniyle yarı metal olarak kabul edilir. Yerkabuğundaki ortalama bor konsantrasyonu 10 mg/kg'dır. Bor doğada Ca, Na ve Mg'un tuzları şeklinde bulunur. Yüksek konsantrasyonlarda ve ekonomik boyutlardaki bor yatakları; borun oksijen ile bağlanmış bileşikleri şeklinde daha çok Türkiye ve ABD'nin kurak, volkanik ve hidrotermal aktivitesi olan bölgelerinde bulunmaktadır. Bor, bitkiler için gerekli bir mikro besin elementi olmanın yanı sıra, gerekli tüm besin elementleri içerisinde, eksiklik belirtilerine neden olan miktarı ile toksik etki yapan miktarı, birbirine çok yakın olan tek elementtir. Bor su ortamında genellikle borik asit ve kısmen de borat tuzları formlarında bulunmaktadır. Pek çok endüstride kullanım alanı bulan bor bileşiklerinin endüstriyel gelişmelere bağlı olarak yüzeysel sularda bulunan konsantrasyonu artış göstermektedir. Yüzeysel sularda bulunan bor aynı zamanda evsel atıksulardan da kaynaklanmaktadır. Türkiye'de içme ve sulama sularını en çok kirleten toksik elementlerin başında bor gelmektedir. Bu nedenle bor giderimi hem insan sağlığı açısından hem de sağlıklı tarım ürünü yetiştirilebilmesi açısından oldukça önemlidir. Sulardan bor giderimi için uygulanan temel yöntemler arasında iyon değişimi, ultrafiltrasyon, ters osmoz ve adsorbsiyon gelmektedir.

  15. Bafa Gölü'nde biyotik ve abiyotik ortamda pestisit ve pcb dağılımı.

    Directory of Open Access Journals (Sweden)

    İdil Pazı

    2015-12-01

    Full Text Available Çalışma kapsamında Bafa Gölü’nden alınan sediment ve kefal balığı (Mugil cephalus, Linnaeus 1758 örneklerinde tarımsal pestisit ve endüstriyel kaynaklı PCB gibi organik kirleticilerin kalıntıları ölçülmüş ve bu bileşiklerin dağılımları, muhtemel kaynakları ve potansiyel biyolojik riskleri incelenmiştir. DDT ve türevleri açısından dünyanın farklı bölgelerindeki göllerin yüzey sedimentleri ile kıyaslandığında Bafa Gölü sedimentlerinde DDT kirlilik seviyesinin oldukça düşük olduğu bulunmuştur. Sedimentte Endrin baskın kirletici olarak belirlenmiştir. Sediment örneklerinde ölçülen DDT ve metabolitleri, Dieldrin, Lindan ve Heptaklor konsantrasyonları sediment kalite indekslerine göre değerlendirildiğinde, kirleticilerin göldeki canlı yaşamına olumsuz bir etkisinin olmadığı belirlenmiştir. ∑PCB konsantrasyonlarının ise göl kıyısında bulunan endüstriyel kuruluşlara yakın istasyonlarda sadece düşük değerli etki sevisini aşıp, diğer tüm istasyonlarda canlılar için risk yaratmayacağı belirlenmiştir. Mugil cephalus karaciğer dokusu için hesaplanan biyota sediment akümülasyon faktörü (BSAF 0.44-3.16 arasında değişmektedir. Bafa Gölü Mugil cephalus örneklerinde ölçülen kirletici konsantrasyonları dikkate alındığında Gıda ve Tarım Kurumu (FAO ve Dünya Sağlık Örgütüne (WHO göre Aldrin, Dieldrin, Endrin, Heptaklor ve DDT türevleri için hesaplanan Günlük Alım Miktarı değerlerinin (EDI Kabul Edilebilir Günlük Alım miktarlarının (ADI oldukça altında kaldığı belirlenmiştir. Ancak, balık örneklerindeki PCB seviyelerinin WHO tarafından belirlenen ADI değerini aştığı saptanmıştır

  16. Negative thermal expansion and its relation to high pressures

    Science.gov (United States)

    Sikka, S. K.

    2004-04-01

    Most materials expand when heated. However, many exceptions are now known. Recently, interest in this has been revived with the discovery of isotropic negative thermal expansion (NTE) in ZrW2O8. From equation of state considerations, one can relate NTE to negative Grüneisen parameters (thermal or electronic). Under pressure, these lead to equation of state anomalies with the pressure derivative of the bulk modules being small or negative. Many of these materials undergo pressure-induced amorphization. This in some of them can be understood on the steric constraint model. It is also argued that NTE in most materials may be understood from the fact that these materials have two degenerate or nearly degenerate energy states. On increase of temperature, the material then samples the lower volume state, leading to NTE.

  17. Negative thermal expansion and its relation to high pressures

    Energy Technology Data Exchange (ETDEWEB)

    Sikka, S K [Office of the Principal Scientific Adviser to the Government of India, 324-A, Vigyan Bhawan Annexe, Maulana Azad Road, New Delhi 110011 (India)

    2004-04-14

    Most materials expand when heated. However, many exceptions are now known. Recently, interest in this has been revived with the discovery of isotropic negative thermal expansion (NTE) in ZrW{sub 2}O{sub 8}. From equation of state considerations, one can relate NTE to negative Grueneisen parameters (thermal or electronic). Under pressure, these lead to equation of state anomalies with the pressure derivative of the bulk modules being small or negative. Many of these materials undergo pressure-induced amorphization. This in some of them can be understood on the steric constraint model. It is also argued that NTE in most materials may be understood from the fact that these materials have two degenerate or nearly degenerate energy states. On increase of temperature, the material then samples the lower volume state, leading to NTE.

  18. CHARACTERIZATION OF REACTIVE FORMATIONS: A VISION FOR THE CAPACITY EXPANSION

    Directory of Open Access Journals (Sweden)

    Danielly Vieira de Lucena

    2013-12-01

    Full Text Available All classes of clay minerals absorb water, but the smectite absorb much larger volumes than the other classes because of its expanded network. During the drilling of oil wells it is common for the detection of layers consisting of clay minerals high grade of hydration arranged in laminar packages. When in contact with water, the packets are separated clay as the water enters the basal spacing. This phenomenon is known as expansion or swelling. Given this, this paper aims to characterize shales in two regions of the country to explain the susceptibility of hydration of each of these formations. The characterization was done by making use of Exchange cation capacity (ECC, X-ray fluorescence (XRF, diferential thermal analysis (DTA, Thermogravimetry (TGA and X-ray diffraction (XRD. The results obtained showed that among the shales studied, those with the greatest degree of clay fractions (smectite in its composition showed higher swelling index according to the methodology of Foster.

  19. Negative thermal expansion materials: technological key for control of thermal expansion.

    Science.gov (United States)

    Takenaka, Koshi

    2012-02-01

    Most materials expand upon heating. However, although rare, some materials contract upon heating. Such negative thermal expansion (NTE) materials have enormous industrial merit because they can control the thermal expansion of materials. Recent progress in materials research enables us to obtain materials exhibiting negative coefficients of linear thermal expansion over -30 ppm K(-1). Such giant NTE is opening a new phase of control of thermal expansion in composites. Specifically examining practical aspects, this review briefly summarizes materials and mechanisms of NTE as well as composites containing NTE materials, based mainly on activities of the last decade.

  20. İnternet’ten İzlenen Dizi ve Seriyallerin “Araç İletidir” ve “Kullanımlar Doyumlar” Bağlamında İncelenmesi

    OpenAIRE

    ÇÖTELİ, Sami

    2016-01-01

    Televizyon izleme pratikleri arasında önemli yere sahip olan dizi film ve seriyallerin İnternet ortamından izlenebilir olması beraberinde akla şu soruyu getiriyor: “İnternet, dizi film ve seriyallerin izlenmesi bakımından doğru bir medya mıdır?” Dizi film ve seriyallerin İnternet üzerinden izlenmesi ile yayın aracına müdahale edilmiş olur ve araçlar bozuma uğrar. Oysaki dizi ve seriyallerin anlatı yapısında bölümü dorukta sonlandırma, izleyiciyi meraklandırma ve gündelik sohbetlere konu olma ...

  1. SU-E-J-221: A Novel Expansion Method for MRI Based Target Delineation in Prostate Radiotherapy

    Energy Technology Data Exchange (ETDEWEB)

    Ruiz, B [Alliance Oncology, Newburyport, MA (United States); East Carolina University, Greenville, NC (United States); Feng, Y [East Carolina University, Greenville, NC (United States); Shores, R [Alliance Oncology, Greenville, MS (United States); Fung, C [Beth Isreal Deaconess Medical Center, Radiation Oncology, Newburyport, MA (United States)

    2015-06-15

    Purpose: To compare a novel bladder/rectum carveout expansion method on MRI delineated prostate to standard CT and expansion based methods for maintaining prostate coverage while providing superior bladder and rectal sparing. Methods: Ten prostate cases were planned to include four trials: MRI vs CT delineated prostate/proximal seminal vesicles, and each image modality compared to both standard expansions (8mm 3D expansion and 5mm posterior, i.e. ∼8mm) and carveout method expansions (5mm 3D expansion, 4mm posterior for GTV-CTV excluding expansion into bladder/rectum followed by additional 5mm 3D expansion to PTV, i.e. ∼1cm). All trials were planned to total dose 7920 cGy via IMRT. Evaluation and comparison was made using the following criteria: QUANTEC constraints for bladder/rectum including analysis of low dose regions, changes in PTV volume, total control points, and maximum hot spot. Results: ∼8mm MRI expansion consistently produced the most optimal plan with lowest total control points and best bladder/rectum sparing. However, this scheme had the smallest prostate (average 22.9% reduction) and subsequent PTV volume, consistent with prior literature. ∼1cm MRI had an average PTV volume comparable to ∼8mm CT at 3.79% difference. Bladder QUANTEC constraints were on average less for the ∼1cm MRI as compared to the ∼8mm CT and observed as statistically significant with 2.64% reduction in V65. Rectal constraints appeared to follow the same trend. Case-by-case analysis showed variation in rectal V30 with MRI delineated prostate being most favorable regardless of expansion type. ∼1cm MRI and ∼8mm CT had comparable plan quality. Conclusion: MRI delineated prostate with standard expansions had the smallest PTV leading to margins that may be too tight. Bladder/rectum carveout expansion method on MRI delineated prostate was found to be superior to standard CT based methods in terms of bladder and rectal sparing while maintaining prostate coverage

  2. Interfacing with in-Situ Data Networks during the Arctic Boreal Vulnerability Experiment (ABoVE)

    Science.gov (United States)

    McInerney, M.; Griffith, P. C.; Duffy, D.; Hoy, E.; Schnase, J. L.; Sinno, S.; Thompson, J. H.

    2014-12-01

    The Arctic Boreal Vulnerability Experiment (ABoVE) is designed to improve understanding of the causes and impacts of ecological changes in Arctic/boreal regions, and will integrate field-based studies, modeling, and data from airborne and satellite remote sensing. ABoVE will result in a fuller understanding of ecosystem vulnerability and resilience to environmental change in the Arctic and boreal regions of western North America, and provide scientific information required to develop options for societal responses to the impacts of these changes. The studies sponsored by NASA during ABoVE will be coordinated with research and in-situ monitoring activities being sponsored by a number of national and international partners. The NASA Center for Climate Simulation at the Goddard Space Flight Center has partnered with the NASA Carbon Cycle & Ecosystems Office to create a science cloud designed for this field campaign - the ABoVE Science Cloud (ASC). The ASC combines high performance computing with emerging technologies to create an environment specifically designed for large-scale modeling, analysis of remote sensing data, copious disk storage with integrated data management, and integration of core variables from in-situ networks identified by the ABoVE Science Definition Team. In this talk, we will present the scientific requirements driving the development of the ABoVE Science Cloud, discuss the necessary interfaces, both computational and human, with in-situ monitoring networks, and show examples of how the ASC is being used to meet the needs of the ABoVE campaign.

  3. Density and molar volumes of imidazolium-based ionic liquid mixtures and prediction by the Jouyban-Acree model

    Science.gov (United States)

    Ghani, Noraini Abd; Sairi, Nor Asrina; Mat, Ahmad Nazeer Che; Khoubnasabjafari, Mehry; Jouyban, Abolghasem

    2016-11-01

    The density of imidazolium-based ionic liquid, 1-ethyl-3-methylimidazolium diethylphosphate with sulfolane were measured at atmospheric pressure. The experiments were performed at T= (293 - 343) K over the complete mole fractions. Physical and thermodynamic properties such as molar volumes, V0, and excess molar volumes, VE for this binary mixtures were derived from the experimental density data. The Jouyban-Acree model was exploited to correlate the physicochemical properties (PCPs) of binary mixtures at various mole fractions and temperatures.

  4. The PREVAIL Study: Primary Outcomes by Site and Extent of Baseline Disease for Enzalutamide-treated Men with Chemotherapy-naïve Metastatic Castration-resistant Prostate Cancer

    DEFF Research Database (Denmark)

    Evans, Christopher P; Higano, Celestia S; Keane, Thomas;

    2016-01-01

    in men with chemotherapy-naïve metastatic castration-resistant prostate cancer, with or without visceral disease, low- or high-volume bone disease, or lymph node only disease. PATIENT SUMMARY: Patients with metastatic castration-resistant prostate cancer-including those with or without visceral disease......BACKGROUND: Enzalutamide, an oral androgen receptor inhibitor, significantly improved overall survival (OS) and radiographic progression-free survival (rPFS) versus placebo in the PREVAIL trial of men with chemotherapy-naïve metastatic castration-resistant prostate cancer. OBJECTIVE: To assess...... the effects of enzalutamide versus placebo in patients from PREVAIL based on site and extent of baseline disease. DESIGN, SETTING, AND PARTICIPANTS: One thousand seven hundred and seventeen asymptomatic or minimally symptomatic patients were randomized to enzalutamide (n=872) or placebo (n=845). Subgroup...

  5. Stem cells. m6A mRNA methylation facilitates resolution of naïve pluripotency toward differentiation.

    Science.gov (United States)

    Geula, Shay; Moshitch-Moshkovitz, Sharon; Dominissini, Dan; Mansour, Abed AlFatah; Kol, Nitzan; Salmon-Divon, Mali; Hershkovitz, Vera; Peer, Eyal; Mor, Nofar; Manor, Yair S; Ben-Haim, Moshe Shay; Eyal, Eran; Yunger, Sharon; Pinto, Yishay; Jaitin, Diego Adhemar; Viukov, Sergey; Rais, Yoach; Krupalnik, Vladislav; Chomsky, Elad; Zerbib, Mirie; Maza, Itay; Rechavi, Yoav; Massarwa, Rada; Hanna, Suhair; Amit, Ido; Levanon, Erez Y; Amariglio, Ninette; Stern-Ginossar, Noam; Novershtern, Noa; Rechavi, Gideon; Hanna, Jacob H

    2015-02-27

    Naïve and primed pluripotent states retain distinct molecular properties, yet limited knowledge exists on how their state transitions are regulated. Here, we identify Mettl3, an N(6)-methyladenosine (m(6)A) transferase, as a regulator for terminating murine naïve pluripotency. Mettl3 knockout preimplantation epiblasts and naïve embryonic stem cells are depleted for m(6)A in mRNAs, yet are viable. However, they fail to adequately terminate their naïve state and, subsequently, undergo aberrant and restricted lineage priming at the postimplantation stage, which leads to early embryonic lethality. m(6)A predominantly and directly reduces mRNA stability, including that of key naïve pluripotency-promoting transcripts. This study highlights a critical role for an mRNA epigenetic modification in vivo and identifies regulatory modules that functionally influence naïve and primed pluripotency in an opposing manner.

  6. Preliminary thermal expansion screening data for tuffs

    Energy Technology Data Exchange (ETDEWEB)

    Lappin, A.R.

    1980-03-01

    A major variable in evaluating the potential of silicic tuffs for use in geologic disposal of heat-producing nuclear wastes is thermal expansion. Results of ambient-pressure linear expansion measurements on a group of tuffs that vary treatly in porosity and mineralogy are presente here. Thermal expansion of devitrified welded tuffs is generally linear with increasing temperature and independent of both porosity and heating rate. Mineralogic factors affecting behavior of these tuffs are limited to the presence or absence of cristobalite and altered biotite. The presence of cristobalite results in markedly nonlinear expansion above 200{sup 0}C. If biotite in biotite-hearing rocks alters even slightly to expandable clays, the behavior of these tuffs near the boiling point of water can be dominated by contraction of the expandable phase. Expansion of both high- and low-porosity tuffs containing hydrated silicic glass and/or expandable clays is complex. The behavior of these rocks appears to be completely dominated by dehydration of hydrous phases and, hence, should be critically dependent on fluid pressure. Valid extrapolation of the ambient-pressure results presented here to depths of interest for construction of a nuclear-waste repository will depend on a good understanding of the interaction of dehydration rates and fluid pressures, and of the effects of both micro- and macrofractures on the response of tuff masss.

  7. The $\\hbar$ Expansion in Quantum Field Theory

    Energy Technology Data Exchange (ETDEWEB)

    Brodsky, Stanley J.; /SLAC /Southern Denmark U., CP3-Origins; Hoyer, Paul; /Southern Denmark U., CP3-Origins /Helsinki U. /Helsinki Inst. of Phys.

    2010-10-27

    We show how expansions in powers of Planck's constant {h_bar} = h = 2{pi} can give new insights into perturbative and nonperturbative properties of quantum field theories. Since {h_bar} is a fundamental parameter, exact Lorentz invariance and gauge invariance are maintained at each order of the expansion. The physics of the {h_bar} expansion depends on the scheme; i.e., different expansions are obtained depending on which quantities (momenta, couplings and masses) are assumed to be independent of {h_bar}. We show that if the coupling and mass parameters appearing in the Lagrangian density are taken to be independent of {h_bar}, then each loop in perturbation theory brings a factor of {h_bar}. In the case of quantum electrodynamics, this scheme implies that the classical charge e, as well as the fine structure constant are linear in {h_bar}. The connection between the number of loops and factors of {h_bar} is more subtle for bound states since the binding energies and bound-state momenta themselves scale with {h_bar}. The {h_bar} expansion allows one to identify equal-time relativistic bound states in QED and QCD which are of lowest order in {h_bar} and transform dynamically under Lorentz boosts. The possibility to use retarded propagators at the Born level gives valence-like wave-functions which implicitly describe the sea constituents of the bound states normally present in its Fock state representation.

  8. Expansion Under Climate Change: The Genetic Consequences.

    Science.gov (United States)

    Garnier, Jimmy; Lewis, Mark A

    2016-11-01

    Range expansion and range shifts are crucial population responses to climate change. Genetic consequences are not well understood but are clearly coupled to ecological dynamics that, in turn, are driven by shifting climate conditions. We model a population with a deterministic reaction-diffusion model coupled to a heterogeneous environment that develops in time due to climate change. We decompose the resulting travelling wave solution into neutral genetic components to analyse the spatio-temporal dynamics of its genetic structure. Our analysis shows that range expansions and range shifts under slow climate change preserve genetic diversity. This is because slow climate change creates range boundaries that promote spatial mixing of genetic components. Mathematically, the mixing leads to so-called pushed travelling wave solutions. This mixing phenomenon is not seen in spatially homogeneous environments, where range expansion reduces genetic diversity through gene surfing arising from pulled travelling wave solutions. However, the preservation of diversity is diminished when climate change occurs too quickly. Using diversity indices, we show that fast expansions and range shifts erode genetic diversity more than slow range expansions and range shifts. Our study provides analytical insight into the dynamics of travelling wave solutions in heterogeneous environments.

  9. A Simple, Reliable, and Inexpensive Intraoperative External Expansion System for Enhanced Autologous Structural Fat Grafting

    Science.gov (United States)

    Oranges, Carlo M.; Tremp, Mathias; Ling, Barbara; Wettstein, Reto; Largo, René D.

    2016-01-01

    External volume expansion of the recipient site by suction has been proposed as a way of improving fat graft survival. The objective of this study was to present an innovative and simple intraoperative external expansion system to enhance small-volume autologous fat grafting (40–80 mL) and to discuss its background and its mechanism of action. In this system, expansion is performed using a complete vacuum delivery system known as the Kiwi VAC-6000M with a PalmPump (Clinical Innovations). The recipient site is rapidly expanded intraoperatively 10 times for 30 seconds each with a negative pressure of up to 550 mm Hg before autologous fat injection. During this repetitive stimulation, the tissues become grossly expanded, developing macroscopic swelling that regresses slowly over the course of hours following the cessation of the stimulus. The system sets various mechanisms in motion, including scar release, mechanical stimulation, edema, ischemia, and inflammation, which provide an environment conducive for cell proliferation and angiogenesis. In order to maintain the graft construct in its expansive state, all patients are encouraged postoperatively to use the Kiwi three times daily for one minute per session over the course of three days. The handling of this system is simple for both the patients and the surgeon. Satisfactory clinical outcomes have been achieved without significant complications. PMID:27689056

  10. Orbitofrontal lobe volume deficits in Antipsychotic-Naive schizophrenia: A 3-Tesla MRI study

    Directory of Open Access Journals (Sweden)

    Behere Rishikesh

    2009-01-01

    Full Text Available Background: Prefrontal cortex deficits have been consistently demonstrated in schizophrenia. The orbitofrontal lobe (OFL, a critical component of the prefrontal cortex, subserves social and neuro-cognitive functions. While these functional impairments are established in schizophrenia, the OFL volume deficits have not been well studied, especially in antipsychotic-naοve patients. Aim: To study OFL volume deficits in antipsychotic-naοve schizophrenia patients in comparison with matched healthy controls using high-resolution 3-tesla (3T magnetic resonance imaging (MRI. Materials and Methods: Fourteen antipsychotic-naοve schizophrenia patients (DSM-IV and 14 age-, sex-, handedness- and education-matched healthy controls were scanned using 3T MRI. Psychopathology was assessed in the patient group using the scale for assessment of negative symptoms and the scale for assessment of positive symptoms (SAPS. The OFL volume was measured using Region of Interest (ROI-based manual morphometry technique, with good inter-rater reliability (intra-class correlation coefficient = 0.98. Results: Total OFL volume was significantly smaller in schizophrenia patients (43.3 ± 9.6 mL in comparison with healthy controls (52.1 ± 12.2 mL after controlling for the potential confounding effects of age, sex and intracranial volume (F = 5.3, P = .03. Duration of untreated psychosis did not correlate significantly with OFL volumes. There was a trend towards significant negative correlation between the left and total OFL volumes and SAPS scores (r = -0.49, P = .06. Conclusion: OFL volume deficits might underlie the pathogenesis of schizophrenia symptoms with possible neuro-developmental origins.

  11. SPOR ALANLARINDA ŞİDDET VE SPOR MEDYASININ ETKİLERİ: SPOR YAZARLARININ ALGILARI

    Directory of Open Access Journals (Sweden)

    Erol İLHAN

    2011-12-01

    Full Text Available Bu çalışmanın amacı, spor alanlarında görülen şiddet olaylarına medyanın etkisini spor yazarlarının algılamaları çerçevesinde ortaya koymaktır. Araştırmanın evrenini ulusal gazete ve dergilerde köşesi bulunan spor yazarları, örneklemini ise ulusal bir gazetede köşesi bulunan, periyodik olarak makale yazan ve tesadüfü yolla seçilen 42 spor yazarı oluşturmuştur. Araştırma görüşmecilerle önceden randevu alınarak yüz yüze görüşme (34 veya telefon aracılığı (8 ile gerçekleştirilmiştir. Görüşmelerde ses kayıt cihazı kullanılmış ve ses kayıtları deşifre edilerek yazılı hale getirilmiştir. Verilerin özgün formuna sadık kalarak beyanlardan alıntı yapılmış ve betimsel bir yaklaşımla sunulmuştur. Bazı nedensel ve açıklayıcı sonuçlara ulaşmak amacıyla sistematik analiz yapılmış ve görüşmeler derinlemesine incelenerek ortak tema ve alt temalar belirlenmeye çalışılmıştır. Nitel araştırmayı nicel verilerle desteklemek amacıyla yüzde ve frekans dağılımları da verilmiştir. Araştırma bulgularına göre spor yazarlarının spor medyasının şiddeti özendirme ve körüklemede etkili olduğu ana temasına 32 spor yazarının (%76,2 katıldığı; alt temalardan şiddeti özendirme ve körüklemede kulüp yöneticilerinin etkisine 24 spor yazarının (%57,1, tiraj ve reyting kaygısının etkisine 10 spor yazarının (%23,8 ve taraftar yazarlığının etkisine 5 spor yazarının (%11,9 inandığı belirlenmiştir. Sonuç olarak, spor yazarlarının önemli bir kısmının spor medyasının spor alanlarında görülen şiddet olaylarını özendirme ve körüklemede etkili olduğuna inandıkları söylenebilir.

  12. KADIN YOKSULLUĞU VE KADIN SAĞLIĞI ÜZERİNE YANSIMALARI

    Directory of Open Access Journals (Sweden)

    Seda KOCABACAK

    2014-08-01

    Full Text Available Cinsiyet eşitsizliği, yoksulluk ve iyi olmayan sağlık durumunun önemli nedenlerinden biridir. Kadınlar sosyal hayatın birçok alanında cinsiyet ayrımcılığı ile karşı karşıya kalırlar: sağlık hizmetlerinden yararlanma, eğitim, istihdam koşulları, sosyal ve ekonomik yaşam, politik haklar ve ahlaki sorumluluklar bunların bazılarıdır. Bazı toplumsal kabuller ya da ailelerin ekonomik zorlukları kız çocukların okuldan uzak kalmasına yol açabilmektedir. Eğitimsizlik ya da yetersiz eğitim ise özel nitelikler gerektirmeyen ya da düşük gelir sağlayan işlerde çalışılmasına yol açmaktadır. Bu kısıtlılıklar ve eşitsizlikler kadın sağlığı ve refahı üzerinde doğrudan ya da dolaylı etkilere sahiptir. Eğitimli ve refah sahibi kadınlar kadın sağlığı, çocuk sağlığı, aile sağlığı ve hatta tüm toplumun sağlığının geliştirilmesine katkı sağlarlar. Bu çalışmanın amacı ilk olarak kadın yoksulluğu ve sağlığı arasındaki ilişkiyi tartışmak ve Türkiye’ye ilişkin verilerle değerlendirmeler yapmaktır.

  13. Nitric Oxide Increases Arterial Endotheial Permeability through Mediating VE-Cadherin Expression during Arteriogenesis.

    Directory of Open Access Journals (Sweden)

    Baolin Yang

    Full Text Available Macrophage invasion is an important event during arteriogenesis, but the underlying mechanism is still only partially understood. The present study tested the hypothesis that nitric oxide (NO and VE-cadherin, two key mediators for vascular permeability, contribute to this event in a rat ischemic hindlimb model. In addition, the effect of NO on expression of VE-caherin and endothelial permeability was also studied in cultured HUVECs. We found that: 1 in normal arteriolar vessels (NAV, eNOS was moderately expressed in endothelial cells (EC and iNOS was rarely detected. In contrast, in collateral vessels (CVs induced by simple femoral artery ligation, both eNOS and iNOS were significantly upregulated (P<0.05. Induced iNOS was found mainly in smooth muscle cells, but also in other vascular cells and macrophages; 2 in NAV VE-cadherin was strongly expressed in EC. In CVs, VE-cadherin was significantly downregulated, with a discontinuous and punctate pattern. Administration of nitric oxide donor DETA NONOate (NONOate further reduced the amounts of Ve-cadherin in CVs, whereas NO synthase inhibitor L-NAME inhibited downregulation of VE-cadherin in CVs; 3 in normal rats Evans blue extravasation (EBE was low in the musculus gracilis, FITC-dextron leakage was not detected in the vascular wall and few macrophages were observed in perivascular space. In contrast, EBE was significantly increased in femoral artery ligation rats, FITC-dextron leakage and increased amounts of macrophages were detected in CVs, which were further enhanced by administration of NONOate, but inhibited by L-NAME supplement; 4 in vitro experiments confirmed that an increase in NO production reduced VE-cadherin expression, correlated with increases in the permeability of HUVECs. In conclusion, our data for the first time reveal the expression profile of VE-cadherin and alterations of vascular permeability in CVs, suggesting that NO-mediated VE-cadherin pathway may be one important

  14. [Forum on tissue expansion. Expansion of the scalp. Surgical techniques and clinical applications].

    Science.gov (United States)

    Foyatier, J L; Delay, E; Comparin, J P; Latarjet, J; Masson, C L

    1993-02-01

    Repair of all forms of alopecia is one of the principal applications of scalp expansion. The authors have inserted 400 expansion prostheses, including 20 in the scalp. The surgical technique, choice of material and various types of flaps are described and illustrated by clinical cases of extensive alopecia.

  15. Influence of MgO-type Expansive Agent Hydration Behaviors on Expansive Properties of Concrete

    Institute of Scientific and Technical Information of China (English)

    LU Xiaolin; GENG Fei; ZHANG Hongbo; CHEN Xiong

    2011-01-01

    The hydration behaviors and expansive properties of MgO-type expansive agent curing at different temperatures and environment were investigated. When the curing temperatures changed from 25℃ to 50 ℃, the conductivities of MgO samples increased from 40 to 80 μ s/cm,and the hydrations of MgO were quickened up obviously. Through SEM observation, the hydration product of MgO cured at 50 ℃ for 28 day was about 2-3 μ m in length. The expansion of pastes with 5% of the MgO-type expansive agent was from 0.36% to 1.01% when the curing temperature changed from 25℃ to 50 ℃. When 8% of the MgO-type expansive agent was added, the early shrinkage of concrete was reduced. The expansion ratio increased with the curing temperature, and the expansive cracking of concrete with MgO-type expansive agent might be decreased by blending fly ash.

  16. Study on the Thermal Expansion and Thermal Cycling of AlNp/Al Composites

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    The AIN particle reinforced aluminum matrix composites with 50% volume fraction were fabricated by squeeze-castingtechnology. The thermal expansion behavior and its response to thermal cycling were studied between 20C and400C. Compared with four theoretical models, the measured CTEs of the composite lie within the elastic boundsat lower temperature and elevated temperature, respectively. Strain hysteresis was observed between heating andcooling curves during cycling. This was attributed primarily to the anelastic behavior of the matrix induced by matrixresidual stresses.

  17. Nitric Oxide Increases Arterial Endotheial Permeability through Mediating VE-Cadherin Expression during Arteriogenesis

    Science.gov (United States)

    Wu, Xiaoqiong; Guan, Yinglu; Zhang, Bin; Cai, Weijun; Schaper, Jutta; Schaper, Wolfgang

    2015-01-01

    Macrophage invasion is an important event during arteriogenesis, but the underlying mechanism is still only partially understood. The present study tested the hypothesis that nitric oxide (NO) and VE-cadherin, two key mediators for vascular permeability, contribute to this event in a rat ischemic hindlimb model. In addition, the effect of NO on expression of VE-caherin and endothelial permeability was also studied in cultured HUVECs. We found that: 1) in normal arteriolar vessels (NAV), eNOS was moderately expressed in endothelial cells (EC) and iNOS was rarely detected. In contrast, in collateral vessels (CVs) induced by simple femoral artery ligation, both eNOS and iNOS were significantly upregulated (PEBE) was low in the musculus gracilis, FITC-dextron leakage was not detected in the vascular wall and few macrophages were observed in perivascular space. In contrast, EBE was significantly increased in femoral artery ligation rats, FITC-dextron leakage and increased amounts of macrophages were detected in CVs, which were further enhanced by administration of NONOate, but inhibited by L-NAME supplement; 4) in vitro experiments confirmed that an increase in NO production reduced VE-cadherin expression, correlated with increases in the permeability of HUVECs. In conclusion, our data for the first time reveal the expression profile of VE-cadherin and alterations of vascular permeability in CVs, suggesting that NO-mediated VE-cadherin pathway may be one important mechanism responsible, at least in part, for macrophage invasion during arteriogenesis. PMID:26133549

  18. Optimum Vehicle Component Integration with InVeST (Integrated Vehicle Simulation Testbed)

    Energy Technology Data Exchange (ETDEWEB)

    Ng, W; Paddack, E; Aceves, S

    2001-12-27

    We have developed an Integrated Vehicle Simulation Testbed (InVeST). InVeST is based on the concept of Co-simulation, and it allows the development of virtual vehicles that can be analyzed and optimized as an overall integrated system. The virtual vehicle is defined by selecting different vehicle components from a component library. Vehicle component models can be written in multiple programming languages running on different computer platforms. At the same time, InVeST provides full protection for proprietary models. Co-simulation is a cost-effective alternative to competing methodologies, such as developing a translator or selecting a single programming language for all vehicle components. InVeST has been recently demonstrated using a transmission model and a transmission controller model. The transmission model was written in SABER and ran on a Sun/Solaris workstation, while the transmission controller was written in MATRIXx and ran on a PC running Windows NT. The demonstration was successfully performed. Future plans include the applicability of Co-simulation and InVeST to analysis and optimization of multiple complex systems, including those of Intelligent Transportation Systems.

  19. ELEKTRİKLİ EV ALETLERİNDE CE UYUMLULUĞU VE BİR UYGULAMA

    Directory of Open Access Journals (Sweden)

    Nazmi EKREN

    2009-01-01

    Full Text Available Hızla gelişen teknoloji, artan rekabet ortamı ve kullanıcının bilinçlenmesi gibi nedenlerden dolayı kaliteli üretim yapmanın gerekliliği günümüzde daha da artmıştır. Ürün kalitesinin ve güvenilirliğinin belgelenmesi tüketici açısından şart olmuştur. Ürün güvenliğinin belgelenmesinde kullanılan birçok belge vardır. Bu belgelerden biri de CE belgesidir. Bu makalede, CE işareti ile ilgili temel bilgi verilmiş ve elektrikli ev aletleri için gerekli CE standartları ve testlerinden bahsedilmiştir. Örnek olarak elektrikli ev aletlerinden tost makinesi ele alınmış, incelenmiştir. Tost makinesine CE belgesi almak için EN60335-2-9 direktifine göre gerekli testler yapılmış ve CE belgesi alınmıştır.

  20. Plasminogen Activator Inhibitor-1 Controls Vascular Integrity by Regulating VE-Cadherin Trafficking.

    Directory of Open Access Journals (Sweden)

    Anna E Daniel

    Full Text Available Plasminogen activator inhibitor-1 (PAI-1, a serine protease inhibitor, is expressed and secreted by endothelial cells. Patients with PAI-1 deficiency show a mild to moderate bleeding diathesis, which has been exclusively ascribed to the function of PAI-1 in down-regulating fibrinolysis. We tested the hypothesis that PAI-1 function plays a direct role in controlling vascular integrity and permeability by keeping endothelial cell-cell junctions intact.We utilized PAI-039, a specific small molecule inhibitor of PAI-1, to investigate the role of PAI-1 in protecting endothelial integrity. In vivo inhibition of PAI-1 resulted in vascular leakage from intersegmental vessels and in the hindbrain of zebrafish embryos. In addition PAI-1 inhibition in human umbilical vein endothelial cell (HUVEC monolayers leads to a marked decrease of transendothelial resistance and disrupted endothelial junctions. The total level of the endothelial junction regulator VE-cadherin was reduced, whereas surface VE-cadherin expression was unaltered. Moreover, PAI-1 inhibition reduced the shedding of VE-cadherin. Finally, we detected an accumulation of VE-cadherin at the Golgi apparatus.Our findings indicate that PAI-1 function is important for the maintenance of endothelial monolayer and vascular integrity by controlling VE-cadherin trafficking to and from the plasma membrane. Our data further suggest that therapies using PAI-1 antagonists like PAI-039 ought to be used with caution to avoid disruption of the vessel wall.