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  1. Altitude Acclimatization and Blood Volume: Effects of Exogenous Erythrocyte Volume Expansion

    National Research Council Canada - National Science Library

    Sawka, M

    1996-01-01

    ...: (a) altitude acclimatization effects on erythrocyte volume and plasma volume; (b) if exogenous erythrocyte volume expansion alters subsequent erythrocyte volume and plasma volume adaptations; (c...

  2. Plasma Volume Expansion Resulting from Intravenous Glucose Tolerance Test

    Directory of Open Access Journals (Sweden)

    Robert G. Hahn

    2011-01-01

    Full Text Available Objective. To quantify the degree of plasma volume expansion that occurs during an intravenous glucose tolerance test (IVGTT. Methods. Twenty healthy volunteers (mean age, 28 years underwent IVGTTs in which 0.3 g/kg of glucose 30% was injected as a bolus over 1 min. Twelve blood samples were collected over 75 min. The plasma glucose and blood hemoglobin concentrations were used to calculate the volume distribution (Vd and the clearance (CL of both the exogenous glucose and the injected fluid volume. Results. The IVGTT caused a virtually instant plasma volume expansion of 10%. The half-life of the glucose averaged 15 min and the plasma volume expansion 16 min. Correction of the fluid kinetic model for osmotic effects after injection reduced CL for the infused volume by 85%, which illustrates the strength of osmosis in allocating fluid back to the intracellular fluid space. Simulations indicated that plasma volume expansion can be reduced to 60% by increasing the injection time from 1 to 5 min and reducing the glucose load from 0.3 to 0.2 g/kg. Conclusion. A regular IVGTT induced an acute plasma volume expansion that peaked at 10% despite the fact that only 50–80 mL of fluid were administered.

  3. In vivo Expansion of Naïve CD4+CD25high FOXP3+ Regulatory T Cells in Patients with Colorectal Carcinoma after IL-2 Administration

    Science.gov (United States)

    Beyer, Marc; Schumak, Beatrix; Weihrauch, Martin R.; Andres, Bettina; Giese, Thomas; Endl, Elmar; Knolle, Percy A.; Classen, Sabine; Limmer, Andreas; Schultze, Joachim L.

    2012-01-01

    Regulatory T cells (Treg cells) are increased in context of malignancies and their expansion can be correlated with higher disease burden and decreased survival. Initially, interleukin 2 (IL-2) has been used as T-cell growth factor in clinical vaccination trials. In murine models, however, a role of IL-2 in development, differentiation, homeostasis, and function of Treg cells was established. In IL-2 treated cancer patients a further Treg-cell expansion was described, yet, the mechanism of expansion is still elusive. Here we report that functional Treg cells of a naïve phenotype - as determined by CCR7 and CD45RA expression - are significantly expanded in colorectal cancer patients. Treatment of 15 UICC stage IV colorectal cancer patients with IL-2 in a phase I/II peptide vaccination trial further enlarges the already increased naïve Treg-cell pool. Higher frequencies of T-cell receptor excision circles in naïve Treg cells indicate IL-2 dependent thymic generation of naïve Treg cells as a mechanism leading to increased frequencies of Treg cells post IL-2 treatment in cancer patients. This finding could be confirmed in naïve murine Treg cells after IL-2 administration. These results point to a more complex regulation of Treg cells in context of IL-2 administration. Future strategies therefore might aim at combining IL-2 therapy with novel strategies to circumvent expansion and differentiation of naïve Treg cells. PMID:22276195

  4. In vivo expansion of naïve CD4+ CD25(high FOXP3+ regulatory T cells in patients with colorectal carcinoma after IL-2 administration.

    Directory of Open Access Journals (Sweden)

    Marc Beyer

    Full Text Available Regulatory T cells (T(reg cells are increased in context of malignancies and their expansion can be correlated with higher disease burden and decreased survival. Initially, interleukin 2 (IL-2 has been used as T-cell growth factor in clinical vaccination trials. In murine models, however, a role of IL-2 in development, differentiation, homeostasis, and function of T(reg cells was established. In IL-2 treated cancer patients a further T(reg-cell expansion was described, yet, the mechanism of expansion is still elusive. Here we report that functional T(reg cells of a naïve phenotype--as determined by CCR7 and CD45RA expression--are significantly expanded in colorectal cancer patients. Treatment of 15 UICC stage IV colorectal cancer patients with IL-2 in a phase I/II peptide vaccination trial further enlarges the already increased naïve T(reg-cell pool. Higher frequencies of T-cell receptor excision circles in naïve T(reg cells indicate IL-2 dependent thymic generation of naïve T(reg cells as a mechanism leading to increased frequencies of T(reg cells post IL-2 treatment in cancer patients. This finding could be confirmed in naïve murine T(reg cells after IL-2 administration. These results point to a more complex regulation of T(reg cells in context of IL-2 administration. Future strategies therefore might aim at combining IL-2 therapy with novel strategies to circumvent expansion and differentiation of naïve T(reg cells.

  5. Effect of volume expansion on systemic hemodynamics and central and arterial blood volume in cirrhosis

    DEFF Research Database (Denmark)

    Møller, S; Bendtsen, F; Henriksen, Jens Henrik Sahl

    1995-01-01

    , and arterial pressure were determined before and during a volume expansion induced by infusion of a hyperosmotic galactose solution. RESULTS: During volume expansion, the central and arterial blood volume increased significantly in patients with class A and controls, whereas no significant change was found...... in patients with either class B or class C. Conversely, the noncentral blood volume increased in patients with class B and C. In both patients and controls, the cardiac output increased and the systemic vascular resistance decreased, whereas the mean arterial blood pressure did not change significantly......BACKGROUND & AIMS: Systemic vasodilatation in cirrhosis may lead to hemodynamic alterations with reduced effective blood volume and decreased arterial blood pressure. This study investigates the response of acute volume expansion on hemodynamics and regional blood volumes in patients with cirrhosis...

  6. External Volume Expansion in Irradiated Tissue: Effects on the Recipient Site.

    Science.gov (United States)

    Chin, Michael S; Lujan-Hernandez, Jorge; Babchenko, Oksana; Bannon, Elizabeth; Perry, Dylan J; Chappell, Ava G; Lo, Yuan-Chyuan; Fitzgerald, Thomas J; Lalikos, Janice F

    2016-05-01

    External volume expansion prepares recipient sites to improve outcomes of fat grafting. For patients receiving radiotherapy after mastectomy, results with external volume expansion vary, and the relationship between radiotherapy and expansion remains unexplored. Thus, the authors developed a new translational model to investigate the effects in chronic skin fibrosis after radiation exposure. Twenty-four SKH1-E mice received 50 Gy of β-radiation to each flank and were monitored until fibrosis developed (8 weeks). External volume expansion was then applied at -25 mmHg to one side for 6 hours for 5 days. The opposite side served as the control. Perfusion changes were assessed with hyperspectral imaging. Mice were euthanized at 5 (n = 12) and 15 days (n = 12) after the last expansion application. Tissue samples were analyzed with immunohistochemistry for CD31 and Ki67, Masson trichrome for skin thickness, and picrosirius red to analyze collagen composition. All animals developed skin fibrosis 8 weeks after radiotherapy and became hypoperfused based on hyperspectral imaging. Expansion induced edema on treated sides after stimulation. Perfusion was decreased by 13 percent on the expansion side (p External volume expansion temporarily reduces perfusion, likely because of transient ischemia or edema. Together with mechanotransduction, these effects encourage a proangiogenic and proliferative environment in fibrotic tissue after radiotherapy in the authors' mouse model. Further studies are needed to assess these changes in fat graft retention.

  7. Effect of external volume expansion on the survival of fat grafts

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    Raghuveer Reddy

    2016-01-01

    Full Text Available Introduction: External volume expansion (EVE is one method, which has been utilised for increasing the survival of adipose tissue grafts. EVE releases positive pressure from the graft and also induces intense levels of edema that decreases diffusion of metabolites essential for graft survival initially. The ideal timing of external volume expansion in relation to the injection of the fat to facilitate survival is not yet clear. Aims and Objectives: This study was undertaken to evaluate and compare the efficacy of external volume expansion applied at variable time points in relation to the injection of the fat. Materials and Methods: Athymic mouse was the animal model and human lipo-aspirate mixed with PRP was used as graft. An indigenous dome shaped silicone device was fabricated to deliver a negative pressure of -30 mm of Hg. The EVE was applied at variable time intervals. At the end of 4 weeks visual, histological and radiological features of the injected fat were compared. The adipose tissue was stained with human vimentin to ascertain the origin of the retained fat. Results: All the grafts, which had EVE, had significantly better volume retention and vascularity. The groups which underwent a delayed EVE or prior expansion followed by concomitant graft injection and expansion showed the most optimal vascularity and graft retention. Conclusions: A delayed EVE or prior expansion followed by concomitant graft injection and expansion may be the most ideal combinations to optimize graft take. However, on account of the relatively small sample size, there was a limitation in drawing statistically significant conclusions for certain variables.

  8. Fluid Volume Expansion and Depletion in Hemodialysis Patients Lack Association with Clinical Parameters

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    Sylvia Kalainy

    2015-12-01

    Full Text Available Background: Achievement of normal volume status is crucial in hemodialysis (HD, since both volume expansion and volume contraction have been associated with adverse outcome and events. Objectives: The objectives of this study are to assess the prevalence of fluid volume expansion and depletion and to identify the best clinical parameter or set of parameters that can predict fluid volume expansion in HD patients. Design: This study is cross-sectional. Setting: This study was conducted in three hemodialysis units. Patients: In this study, there are 194 HD patients. Methods: Volume status was assessed by multifrequency bio-impedance spectroscopy (The Body Composition Monitor, Fresenius prior to the mid-week HD session. Results: Of all patients, 48 % ( n = 94 were volume-expanded and 9 % of patients were volume-depleted ( n = 17. Interdialytic weight gain was not different between hypovolemic, normovolemic, and hypervolemic patients. Fifty percent of the volume-expanded patients were hypertensive. Paradoxical hypertension was very common (31 % of all patients; its incidence was not different between patient groups. Intradialytic hypotension was relatively common and was more frequent among hypovolemic patients. Multivariate regression analysis identified only four predictors for volume expansion (edema, lower BMI, higher SBP, and smoking. None of these parameters displayed both a good sensitivity and specificity. Limitations: The volume assessment was performed once. Conclusions: The study indicates that volume expansion is highly prevalent in HD population and could not be identified using clinical parameters alone. No clinical parameters were identified that could reliably predict volume status. This study shows that bio-impedance can assist to determine volume status. Volume status, in turn, is not related to intradialytic weight gain and is unable to explain the high incidence of paradoxical hypertension.

  9. Review article: volume expansion in patients with cirrhosis

    DEFF Research Database (Denmark)

    Henriksen, Jens Henrik Sahl; Kiszka-Kanowitz, Marianne; Bendtsen, Flemming

    2002-01-01

    with low systemic vascular resistance, increased whole-body vascular compliance, and increased arterial compliance. The effectiveness and temporal relations of plasma/blood volume expansion depend highly on the type of load (water, saline, oncotic material, red blood cells). Patients with cirrhosis respond...... in advanced cirrhosis is qualitatively and quantitatively different from that of healthy subjects, and in those with early cirrhosis. Timely handling is essential, but difficult as it is a balance between the risks of excess extravascular volume loading and further circulatory dysfunction in these patients...

  10. Orbitofrontal cortex volumes in medication naïve children with major depressive disorder: a magnetic resonance imaging study.

    Science.gov (United States)

    Chen, Hua-Hsuan; Rosenberg, David R; MacMaster, Frank P; Easter, Philip C; Caetano, Sheila C; Nicoletti, Mark; Hatch, John P; Nery, Fabiano G; Soares, Jair C

    2008-12-01

    Adults with major depressive disorder (MDD) are reported to have reduced orbitofrontal cortex (OFC) volumes, which could be related to decreased neuronal density. We conducted a study on medication naïve children with MDD to determine whether abnormalities of OFC are present early in the illness course. Twenty seven medication naïve pediatric Diagnostic and Statistical Manual of Mental Disorders, 4(th) edition (DSM-IV) MDD patients (mean age +/- SD = 14.4 +/- 2.2 years; 10 males) and 26 healthy controls (mean age +/- SD = 14.4 +/- 2.4 years; 12 males) underwent a 1.5T magnetic resonance imaging (MRI) with 3D spoiled gradient recalled acquisition. The OFC volumes were compared using analysis of covariance with age, gender, and total brain volume as covariates. There was no significant difference in either total OFC volume or total gray matter OFC volume between MDD patients and healthy controls. Exploratory analysis revealed that patients had unexpectedly larger total right lateral (F = 4.2, df = 1, 48, p = 0.05) and right lateral gray matter (F = 4.6, df = 1, 48, p = 0.04) OFC volumes compared to healthy controls, but this finding was not significant following statistical correction for multiple comparisons. No other OFC subregions showed a significant difference. The lack of OFC volume abnormalities in pediatric MDD patients suggests the abnormalities previously reported for adults may develop later in life as a result of neural cell loss.

  11. Impact of Medicaid Expansion on Cardiac Surgery Volume and Outcomes.

    Science.gov (United States)

    Charles, Eric J; Johnston, Lily E; Herbert, Morley A; Mehaffey, J Hunter; Yount, Kenan W; Likosky, Donald S; Theurer, Patricia F; Fonner, Clifford E; Rich, Jeffrey B; Speir, Alan M; Ailawadi, Gorav; Prager, Richard L; Kron, Irving L

    2017-10-01

    Thirty-one states approved Medicaid expansion after implementation of the Affordable Care Act. The objective of this study was to evaluate the effect of Medicaid expansion on cardiac surgery volume and outcomes comparing one state that expanded to one that did not. Data from the Virginia (nonexpansion state) Cardiac Services Quality Initiative and the Michigan (expanded Medicaid, April 2014) Society of Thoracic and Cardiovascular Surgeons Quality Collaborative were analyzed to identify uninsured and Medicaid patients undergoing coronary bypass graft or valve operations, or both. Demographics, operative details, predicted risk scores, and morbidity and mortality rates, stratified by state and compared across era (preexpansion: 18 months before vs postexpansion: 18 months after), were analyzed. In Virginia, there were no differences in volume between eras, whereas in Michigan, there was a significant increase in Medicaid volume (54.4% [558 of 1,026] vs 84.1% [954 of 1,135], p Medicaid patients, there were no differences in predicted risk of morbidity or mortality or postoperative major morbidities. In Michigan Medicaid patients, a significant decrease in predicted risk of morbidity or mortality (11.9% [8.1% to 20.0%] vs 11.1% [7.7% to 17.9%], p = 0.02) and morbidities (18.3% [102 of 558] vs 13.2% [126 of 954], p = 0.008) was identified. Postexpansion was associated with a decreased risk-adjusted rate of major morbidity (odds ratio, 0.69; 95% confidence interval, 0.51 to 0.91; p = 0.01) in Michigan Medicaid patients. Medicaid expansion was associated with fewer uninsured cardiac surgery patients and improved predicted risk scores and morbidity rates. In addition to improving health care financing, Medicaid expansion may positively affect patient care and outcomes. Copyright © 2017 The Society of Thoracic Surgeons. Published by Elsevier Inc. All rights reserved.

  12. The study of the volume expansion of aluminum during porous oxide formation at galvanostatic regime

    Energy Technology Data Exchange (ETDEWEB)

    Vrublevsky, I.; Parkoun, V.; Sokol, V.; Schreckenbach, J.; Marx, G

    2004-01-30

    The volume expansion factor of porous alumina, formed by through anodizing of an Al foil of thickness 11.5 {mu}m in the range of current densities of 4-35 mA cm{sup -2} in oxalic and sulfuric acid at 18-24 deg. C has been studied. The microstructure of anodizing samples has been observed using scanning electron microscopy. The thickness of obtained porous alumina films was measured by a mechanical profilometer with a computer signal-processing. The volume expansion factor of porous alumina varied from 1.35 to 1.65. Linear dependences were obtained for the volume expansion factor of porous alumina versus the anodizing voltage and the ionic current-density logarithm versus the inverse volume expansion factor. Unlike oxide formation in sulfuric acid, these dependences have two subsequential rectilinear regions in oxalic acid. This peculiarity of the dependences in oxalic acid was explained by formation of a region of the immobile negative space charge in the barrier Al oxide layer and its influence on the ionic transport.

  13. Acute volume expansion preserves orthostatic tolerance during whole-body heat stress in humans.

    Science.gov (United States)

    Keller, David M; Low, David A; Wingo, Jonathan E; Brothers, R Matthew; Hastings, Jeff; Davis, Scott L; Crandall, Craig G

    2009-03-01

    Whole-body heat stress reduces orthostatic tolerance via a yet to be identified mechanism(s). The reduction in central blood volume that accompanies heat stress may contribute to this phenomenon. The purpose of this study was to test the hypothesis that acute volume expansion prior to the application of an orthostatic challenge attenuates heat stress-induced reductions in orthostatic tolerance. In seven normotensive subjects (age, 40 +/- 10 years: mean +/- S.D.), orthostatic tolerance was assessed using graded lower-body negative pressure (LBNP) until the onset of symptoms associated with ensuing syncope. Orthostatic tolerance (expressed in cumulative stress index units, CSI) was determined on each of 3 days, with each day having a unique experimental condition: normothermia, whole-body heating, and whole-body heating + acute volume expansion. For the whole-body heating + acute volume expansion experimental day, dextran 40 was rapidly infused prior to LBNP sufficient to return central venous pressure to pre-heat stress values. Whole-body heat stress alone reduced orthostatic tolerance by approximately 80% compared to normothermia (938 +/- 152 versus 182 +/- 57 CSI; mean +/- S.E.M., P body heating completely ameliorated the heat stress-induced reduction in orthostatic tolerance (1110 +/- 69 CSI, P stress results in many cardiovascular and neural responses that directionally challenge blood pressure regulation, reduced central blood volume appears to be an underlying mechanism responsible for impaired orthostatic tolerance in the heat-stressed human.

  14. Relationship between Interleukin-6 gene polymorphism and hippocampal volume in antipsychotic-naïve schizophrenia: evidence for differential susceptibility?

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    Sunil Vasu Kalmady

    Full Text Available Various lines of evidence including epidemiological, genetic and foetal pathogenetic models suggest a compelling role for Interleukin-6 (IL-6 in the pathogenesis of schizophrenia. IL-6 mediated inflammatory response triggered by maternal infection or stress induces disruption of prenatal hippocampal development which might contribute towards psychopathology during adulthood. There is a substantial lack of knowledge on how genetic predisposition to elevated IL-6 expression effects hippocampal structure in schizophrenia patients. In this first-time study, we evaluated the relationship between functional polymorphism rs1800795 of IL-6 and hippocampal gray matter volume in antipsychotic-naïve schizophrenia patients in comparison with healthy controls.We examined antipsychotic-naïve schizophrenia patients [N = 28] in comparison with healthy controls [N = 37] group matched on age, sex and handedness. Using 3 Tesla - MRI, bilateral hippocampi were manually segmented by blinded raters with good inter-rater reliability using a valid method. Additionally, Voxel-based Morphometry (VBM analysis was performed using hippocampal mask. The IL-6 level was measured in blood plasma using ELISA technique. SNP rs1800795 was genotyped using PCR and DNA sequencing. Psychotic symptoms were assessed using Scale for Assessment of Positive Symptoms and Scale for Assessment of Negative Symptoms.Schizophrenia patients had significantly deficient left and right hippocampal volumes after controlling for the potential confounding effects of age, sex and total brain volume. Plasma IL-6 levels were significantly higher in patients than controls. There was a significant diagnosis by rs1800795 genotype interaction involving both right and left hippocampal volumes. Interestingly, this effect was significant only in men but not in women.Our first time observations suggest a significant relationship between IL-6 rs1800795 and reduced hippocampal volume in antipsychotic-naïve

  15. Does hyrax expansion therapy affect maxillary sinus volume? A cone-beam computed tomography report

    International Nuclear Information System (INIS)

    Darsey, Drew M.; English, Jeryl D.; Ellis, Randy K.; Akyalcin, Sercan; Kau, Chung H

    2012-01-01

    The aim of this study was to investigate the initial effects of maxillary expansion therapy with Hyrax appliance and to evaluate the related changes in maxillary sinus volume. Thirty patients (20 females, 10 males; 13.8 years) requiring maxillary expansion therapy, as part of their comprehensive orthodontic treatment, were examined. Each patient had cone-beam computed tomography (CBCT) images taken before (T1) and after (T2) maxillary expansion therapy with a banded Hyrax appliance. Multiplanar slices were used to measure linear dimensions and palatal vault angle. Volumetric analysis was used to measure maxillary sinus volumes. Student t tests were used to compare the pre- and post-treatment measurements. Additionally, differences between two age groups were compared with Mann-Whitney U test. The level of significance was set at p=0.05. Comparison of pre-treatment to post-treatment variables revealed significant changes in the transverse dimension related to both maxillary skeletal and dental structures and palatal vault angle, resulting in a widened palatal vault (p<0.05). Hard palate showed no significant movement in the vertical and anteroposterior planes. Nasal cavity width increased on a mean value of 0.93 mm(SD=0.23, p<0.05). Maxillary sinus volume remained virtually stable. No significant age differences were observed in the sample. Hyrax expansion therapy did not have a significant impact on maxillary sinus volume.

  16. Does hyrax expansion therapy affect maxillary sinus volume? A cone-beam computed tomography report

    Energy Technology Data Exchange (ETDEWEB)

    Darsey, Drew M.; English, Jeryl D.; Ellis, Randy K.; Akyalcin, Sercan [School of Dentistry, University of Texas Health Science Center at Houston, Houston (United States); Kau, Chung H [School of Dentistry, University of Alabama at Birmingham, Birmingham (United States)

    2012-06-15

    The aim of this study was to investigate the initial effects of maxillary expansion therapy with Hyrax appliance and to evaluate the related changes in maxillary sinus volume. Thirty patients (20 females, 10 males; 13.8 years) requiring maxillary expansion therapy, as part of their comprehensive orthodontic treatment, were examined. Each patient had cone-beam computed tomography (CBCT) images taken before (T1) and after (T2) maxillary expansion therapy with a banded Hyrax appliance. Multiplanar slices were used to measure linear dimensions and palatal vault angle. Volumetric analysis was used to measure maxillary sinus volumes. Student t tests were used to compare the pre- and post-treatment measurements. Additionally, differences between two age groups were compared with Mann-Whitney U test. The level of significance was set at p=0.05. Comparison of pre-treatment to post-treatment variables revealed significant changes in the transverse dimension related to both maxillary skeletal and dental structures and palatal vault angle, resulting in a widened palatal vault (p<0.05). Hard palate showed no significant movement in the vertical and anteroposterior planes. Nasal cavity width increased on a mean value of 0.93 mm(SD=0.23, p<0.05). Maxillary sinus volume remained virtually stable. No significant age differences were observed in the sample. Hyrax expansion therapy did not have a significant impact on maxillary sinus volume.

  17. Central venous pressure and shock index predict lack of hemodynamic response to volume expansion in septic shock: a prospective, observational study.

    Science.gov (United States)

    Lanspa, Michael J; Brown, Samuel M; Hirshberg, Eliotte L; Jones, Jason P; Grissom, Colin K

    2012-12-01

    Volume expansion is a common therapeutic intervention in septic shock, although patient response to the intervention is difficult to predict. Central venous pressure (CVP) and shock index have been used independently to guide volume expansion, although their use is questionable. We hypothesize that a combination of these measurements will be useful. In a prospective, observational study, patients with early septic shock received 10-mL/kg volume expansion at their treating physician's discretion after brief initial resuscitation in the emergency department. Central venous pressure and shock index were measured before volume expansion interventions. Cardiac index was measured immediately before and after the volume expansion using transthoracic echocardiography. Hemodynamic response was defined as an increase in a cardiac index of 15% or greater. Thirty-four volume expansions were observed in 25 patients. A CVP of 8 mm Hg or greater and a shock index of 1 beat min(-1) mm Hg(-1) or less individually had a good negative predictive value (83% and 88%, respectively). Of 34 volume expansions, the combination of both a high CVP and a low shock index was extremely unlikely to elicit hemodynamic response (negative predictive value, 93%; P = .02). Volume expansion in patients with early septic shock with a CVP of 8 mm Hg or greater and a shock index of 1 beat min(-1) mm Hg(-1) or less is unlikely to lead to an increase in cardiac index. Copyright © 2012 Elsevier Inc. All rights reserved.

  18. Volume weighting the measure of the universe from classical slow-roll expansion

    Science.gov (United States)

    Sloan, David; Silk, Joseph

    2016-05-01

    One of the most frustrating issues in early universe cosmology centers on how to reconcile the vast choice of universes in string theory and in its most plausible high energy sibling, eternal inflation, which jointly generate the string landscape with the fine-tuned and hence relatively small number of universes that have undergone a large expansion and can accommodate observers and, in particular, galaxies. We show that such observations are highly favored for any system whereby physical parameters are distributed at a high energy scale, due to the conservation of the Liouville measure and the gauge nature of volume, asymptotically approaching a period of large isotropic expansion characterized by w =-1 . Our interpretation predicts that all observational probes for deviations from w =-1 in the foreseeable future are doomed to failure. The purpose of this paper is not to introduce a new measure for the multiverse, but rather to show how what is perhaps the most natural and well-known measure, volume weighting, arises as a consequence of the conservation of the Liouville measure on phase space during the classical slow-roll expansion.

  19. Temperature dependence of volume thermal expansion for NaCl and KCl crystals

    International Nuclear Information System (INIS)

    Fang Zhenghua

    2005-01-01

    A new relation for predicting volume thermal expansion of alkali halides at high temperatures is derived based on the assumption that the two different diffusional driving force models presented, respectively, by Sharma and Sharma (Indian J. Pure Appl. Phys. 29 (1991) 637) and Singh (J. Phys. Chem. Solids 63 (2002) 1935) are equivalent. The input parameters needed for the calculation are the volume thermal expansion coefficient and the isothermal Anderson-Gruneisen parameter, both at room temperature and zero pressure, which are available from the literature. The tests on NaCl and KCl crystals demonstrate that the agreement between the calculated results obtained by this relation and the corresponding experimental data is very good. The applicability of the relation as well as some thermodynamic relationships included in its derivation is discussed

  20. Tumor-associated mesenchymal stem cells inhibit naïve T cell expansion by blocking cysteine export from dendritic cells.

    Science.gov (United States)

    Ghosh, Tithi; Barik, Subhasis; Bhuniya, Avishek; Dhar, Jesmita; Dasgupta, Shayani; Ghosh, Sarbari; Sarkar, Madhurima; Guha, Ipsita; Sarkar, Koustav; Chakrabarti, Pinak; Saha, Bhaskar; Storkus, Walter J; Baral, Rathindranath; Bose, Anamika

    2016-11-01

    Mesenchymal stem cells (MSCs) represent an important cellular constituent of the tumor microenvironment, which along with tumor cells themselves, serve to regulate protective immune responses in support of progressive disease. We report that tumor MSCs prevent the ability of dendritic cells (DC) to promote naïve CD4(+) and CD8(+) T cell expansion, interferon gamma secretion and cytotoxicity against tumor cells, which are critical to immune-mediated tumor eradication. Notably, tumor MSCs fail to prevent DC-mediated early T cell activation events or the ability of responder T cells to produce IL-2. The immunoregulatory activity of tumor MSCs is IL-10- and STAT3-dependent, with STAT3 repressing DC expression of cystathionase, a critical enzyme that converts methionine-to-cysteine. Under cysteine-deficient priming conditions, naïve T cells exhibit defective cellular metabolism and proliferation. Bioinformatics analyses as well as in vitro observations suggest that STAT3 may directly bind to a GAS-like motif within the cystathionase promoter (-269 to -261) leading to IL-10-STAT3 mediated repression of cystathionase gene transcription. Our collective results provide evidence for a novel mechanism of tumor MSC-mediated T cell inhibition within tumor microenvironment. © 2016 UICC.

  1. Increased ANF secretion after volume expansion is preserved in rats with heart failure

    International Nuclear Information System (INIS)

    Chien, Young Wei; Barbee, R.W.; MacPhee, A.L.; Frohlich, E.D.; Trippodo, N.C.

    1988-01-01

    To examine whether the failing heart has reached a maximal capacity to increase plasma atrial natriuretic factor (ANF) concentration, the change in plasma immunoreactive ANF, measured by radioimmunoassay level due to acute blood volume expansion was determined in conscious rats with chronic heart failure. Varying degrees of myocardial infarction and thus heart failure were induced by coronary artery ligation 3 wk before study. Compared with controls, infarcted rats had decreases in mean arterial pressure cardiac index, renal blood flow, and peak left ventricle-developed pressure after aortic occlusion, and increases in central venous pressure, left ventricular end-diastolic pressure, total peripheral resistance, plasma ANF level. Plasma ANF was correlated with infarct size, cardiac filling pressures, and left ventricle pressure-generating ability. At 5 min after 25% blood volume expansion, plasma ANF in rats with heart failure increased by 2,281 ± 345 pg/ml; the magnitude of the changes in circulating ANF and hemodynamic measurements was similar in controls. The results suggest that plasma ANF level can be used as a reliable index of the severity of heart failure, and that the capacity to increase plasma ANF concentration after acute volume expansion is preserved in rats with heart failure. There was no evidence of a relative deficiency of circulating ANF in this model of heart failure

  2. The volume of fluid injected into the tissue expander and the tissue expansion

    Directory of Open Access Journals (Sweden)

    Mahmood Omranifard

    2014-01-01

    Full Text Available Background: Replacement of the lost tissue is the major concerns of the plastic surgeons. Expanded area should be coherent with the surrounding tissue. Tissue expansion technique is the reforming methods the skin tissue scarcities. Several methods for tissue expansion are available; including usage of silicon balloon and injecting fluid into the tissue expander. Materials and Methods: In a clinical trial study, 35 patients, with burn scars, in the face, skull and neck area were studied. We provided a tissue expander device with capacities of 125, 250 and 350cc. Fluid was injected inside the device, 3 consecutive weeks with 1-week interval. After 3 months the device was set out and the tissue expansion was measured using a transparent board and the results were analyzed. Multiple regression was done by SPSS 20 to analyze the data. Results: Regression model showed Skin expansion was positively correlated with the volume of the injected fluid. For each centimeter square of skin expansion, about 6-8 ml of fluid must be injected. Conclusion: Correction of skin defects resulting from burning scar is possible using tissue expanders. The tissue expansion is correlated with the amount of the injected fluid.

  3. Acute volume expansion attenuates hyperthermia-induced reductions in cerebral perfusion during simulated hemorrhage

    DEFF Research Database (Denmark)

    Schlader, Zachary J; Seifert, Thomas; Wilson, Thad E

    2013-01-01

    Hyperthermia reduces the capacity to withstand a simulated hemorrhagic challenge, but volume loading preserves this capacity. This study tested the hypotheses that acute volume expansion during hyperthermia increases cerebral perfusion and attenuates reductions in cerebral perfusion during...... infusion while hyperthermic. Primary dependent variables were mean middle cerebral artery blood velocity (MCAvmean), serving as an index of cerebral perfusion; mean arterial pressure (MAP); and cardiac output (thermodilution). During baseline, hyperthermia reduced MCAvmean (P = 0.001) by 12 ± 9% relative...

  4. Humoral Na+-K+ pump inhibitory activity in essential hypertension and in normotensive subjects after acute volume expansion

    International Nuclear Information System (INIS)

    Pamnani, M.B.; Burris, J.F.; Jemionek, J.F.; Huot, S.J.; Price, M.; Freis, E.D.; Haddy, F.J.

    1989-01-01

    Plasma from black male patients with essential hypertension was bioassayed for vascular Na+-K+ pump inhibitory activity. Halves of the same rat tail artery were incubated for two hours in boiled plasma supernates from a hypertensive patient and a paired age-, sex-, and race-matched normotensive subject and then ouabain-sensitive 86 Rb uptake was measured. Ouabain-sensitive 86 Rb uptake by their leukocytes was also measured. Eighteen pairs of subjects were studied. The uptakes were not significantly different in the hypertensive patients and control subjects. However, when we selected from the eighteen hypertensive patients, nine with low plasma renin activity on the day of the study, uptakes were reduced in the hypertensive patients relative to the paired control subjects. We also assayed plasma supernates from normotensive black and white male subjects before and after acute volume expansion (2.5 L saline IV + 1.5 L distilled water orally over a three-hour period) and from paired normotensive subjects before and after sham volume expansion and obtained a positive bioassay in the expanded subjects both on intraindividual and interindividual comparisons. These studies demonstrate increased vascular Na+-K+ pump inhibitory activity in the plasma of black male patients with low renin essential hypertension and in the plasma of normotensive subjects after acute volume expansion. The findings suggest that the inhibitory activity in the hypertensive subjects' plasma is related to volume expansion, relative or absolute

  5. Influence of anodization parameters on the volume expansion of anodic aluminum oxide formed in mixed solution of phosphoric and oxalic acids

    Science.gov (United States)

    Kao, Tzung-Ta; Chang, Yao-Chung

    2014-01-01

    The growth of anodic alumina oxide was conducted in the mixed solution of phosphoric and oxalic acids. The influence of anodizing voltage, electrolyte temperature, and concentration of phosphoric and oxalic acids on the volume expansion of anodic aluminum oxide has been investigated. Either anodizing parameter is chosen to its full extent of range that allows the anodization process to be conducted without electric breakdown and to explore the highest possible volume expansion factor. The volume expansion factors were found to vary between 1.25 and 1.9 depending on the anodizing parameters. The variation is explained in connection with electric field, ion transport number, temperature effect, concentration, and activity of acids. The formation of anodic porous alumina at anodizing voltage 160 V in 1.1 M phosphoric acid mixed with 0.14 M oxalic acid at 2 °C showed the peak volume expansion factor of 1.9 and the corresponding moderate growth rate of 168 nm/min.

  6. Neuroendocrine and renal effects of intravascular volume expansion in compensated heart failure

    DEFF Research Database (Denmark)

    Gabrielsen, A; Bie, P; Holstein-Rathlou, N H

    2001-01-01

    To examine if the neuroendocrine link between volume sensing and renal function is preserved in compensated chronic heart failure [HF, ejection fraction 0.29 +/- 0.03 (mean +/- SE)] we tested the hypothesis that intravascular and central blood volume expansion by 3 h of water immersion (WI) elicits...... sustained angiotensin-converting enzyme inhibitor therapy, n = 9) absolute and fractional sodium excretion increased (P Renal free water clearance increased during WI in control subjects but not in HF......, albeit plasma vasopressin concentrations were similar in the two groups. In conclusion, the neuroendocrine link between volume sensing and renal sodium excretion is preserved in compensated HF. The natriuresis of WI is, however, modulated by the prevailing ANG II and Aldo concentrations. In contrast...

  7. Plasma volume expansion does not increase maximal cardiac output or VO2 max in lowlanders acclimatized to altitude

    DEFF Research Database (Denmark)

    Calbet, José A L; Rådegran, Göran; Boushel, Robert Christopher

    2004-01-01

    liter of 6% dextran 70 (BV = 6.32 +/- 0.34 liters). PV expansion had no effect on Qmax, maximal O2 consumption (VO2), and exercise capacity. Despite maximal systemic O2 transport being reduced 19% due to hemodilution after PV expansion, whole body VO2 was maintained by greater systemic O2 extraction (P...... VO2 during exercise regardless of PV. Pulmonary ventilation, gas exchange, and acid-base balance were essentially unaffected by PV expansion. Sea......With altitude acclimatization, blood hemoglobin concentration increases while plasma volume (PV) and maximal cardiac output (Qmax) decrease. This investigation aimed to determine whether reduction of Qmax at altitude is due to low circulating blood volume (BV). Eight Danish lowlanders (3 females, 5...

  8. Sustained volume expansion and [Na,K]ATPase inhibition in chronic renal failure.

    Science.gov (United States)

    Glatter, K A; Graves, S W; Hollenberg, N K; Soszynski, P A; Tao, Q F; Frem, G J; Williams, G H; Lazarus, J M

    1994-11-01

    Hypotheses regarding the pathogenesis of volume-dependent hypertension have invoked an endogenous sodium pump inhibitor or digitalis-like factor (DLF) to link altered sodium homeostasis to the rise in blood pressure. Our goal was to develop a clinical protocol that achieved predictable, sustained volume expansion, with the premise that renal failure patients on peritoneal dialysis would increase intravascular volume, gain weight, and raise blood pressure (BP) in relation to measured increases in DLF. In a 5-day protocol, dialysis was kept constant but dietary NaCl and fluids were modified in 7 patients. DLF was measured as inhibition of [Na,K]ATPase. Likewise, the first 2 L of daily peritoneal dialysate (PD) was processed on HPLC and the eluate analyzed for DLF. The group achieved significant weight gain (WT) by day 3 (delta WT = 4.1 +/- 1.2 kg, P < .05). Likewise, mean arterial pressure (MAP) and plasma DLF activity increased significantly. All variables were highly correlated (DLF v WT: R = 0.88, P = .004; MAP v DLF: R = 0.82, P = .01; MAP v WT: R = 0.90, P = .003). Although a number of HPLC fractions contained agents that interacted with the assay, only one PD HPLC fraction (at 19.5 min) contained DLF activity that correlated with changes in MAP (R = 0.60, P = .002), and body weight (R = 0.67, P = .0003). We conclude that candidate DLF responds to sustained volume expansion and the relationship suggests that it could influence blood pressure. Moreover, the application of stringent criteria to the confusing array of factors in plasma that may affect assays for DLF appears to reduce the field dramatically, to a single candidate in this setting.

  9. Molar volume, thermal expansivity and isothermal compressibility of trans-decahydronaphthalene up to 200MPa and 446K

    Institute of Scientific and Technical Information of China (English)

    Zhu Hu-Gang; Liu Zhi-Hua; Tian Yi-Ling; Xue Yuan; Yin Liang

    2005-01-01

    The molar volume isotherms of trans-decahydronaphthalene (C10H18) between 293 and 446 K and at pressures from 10 to 200 MPa have been determined. A modified Tait equation of state is used to fit each experimental molar volume isotherm with a maximum average deviation of 0.029%. The thermal expansivity (cubic expansion coefficient) α and isothermal compressibility κ were determined by fitting the slopes of the isobaric curves and isotherms, respectively.The coefficients in the equation Vm = C1 + C2T + C3T2 - C4p - C5pT have been fitted with an average deviation of 1.03%.

  10. Establishing pathological cut-offs for lateral ventricular volume expansion rates

    Directory of Open Access Journals (Sweden)

    Michael G. Dwyer

    Full Text Available Background: A percent brain volume change (PBVC cut-off of −0.4% per year has been proposed to distinguish between pathological and physiological changes in multiple sclerosis (MS. Unfortunately, standardized PBVC measurement is not always feasible on scans acquired outside research studies or academic centers. Percent lateral ventricular volume change (PLVVC is a strong surrogate measure of PBVC, and may be more feasible for atrophy assessment on real-world scans. However, the PLVVC rate corresponding to the established PBVC cut-off of −0.4% is unknown. Objective: To establish a pathological PLVVC expansion rate cut-off analogous to −0.4% PBVC. Methods: We used three complementary approaches. First, the original follow-up-length-weighted receiver operating characteristic (ROC analysis method establishing whole brain atrophy rates was adapted to a longitudinal ventricular atrophy dataset of 177 relapsing-remitting MS (RRMS patients and 48 healthy controls. Second, in the same dataset, SIENA PBVCs were used with non-linear regression to directly predict the PLVVC value corresponding to −0.4% PBVC. Third, in an unstandardized, real world dataset of 590 RRMS patients from 33 centers, the cut-off maximizing correspondence to PBVC was found. Finally, correspondences to clinical outcomes were evaluated in both datasets. Results: ROC analysis suggested a cut-off of 3.09% (AUC = 0.83, p < 0.001. Non-linear regression R2 was 0.71 (p < 0.001 and a − 0.4% PBVC corresponded to a PLVVC of 3.51%. A peak in accuracy in the real-world dataset was found at a 3.51% PLVVC cut-off. Accuracy of a 3.5% cut-off in predicting clinical progression was 0.62 (compared to 0.68 for PBVC. Conclusions: Ventricular expansion of between 3.09% and 3.51% on T2-FLAIR corresponds to the pathological whole brain atrophy rate of 0.4% for RRMS. A conservative cut-off of 3.5% performs comparably to PBVC for clinical outcomes. Keywords: Brain atrophy

  11. Densities, molar volumes, and isobaric expansivities of (d-xylose+hydrochloric acid+water) systems

    International Nuclear Information System (INIS)

    Zhang Qiufen; Yan Zhenning; Wang Jianji; Zhang Hucheng

    2006-01-01

    Densities of (d-xylose+HCl+water) have been measured at temperature in the range (278.15 to 318.15) K as a function of concentration of both d-xylose and hydrochloric acid. The densities have been used to estimate the molar volumes and isobaric expansivity of the ternary solutions. The molar volumes of the ternary solutions vary linearly with mole fraction of d-xylose. The standard partial molar volumes V 2,φ - bar for d-xylose in aqueous solutions of molality (0.2, 0.4, 0.7, 1.1, 1.6, and 2.1) mol.kg -1 HCl have been determined. In the investigated temperature range, the relation: V 2,φ - bar =c 1 +c 2 {(T/K)-273.15} 1/2 , can be used to describe the temperature dependence of the standard partial molar volumes. These results have, in conjunction with the results obtained in water, been used to deduce the standard volumes of transfer, Δ t V - bar , of d-xylose from water to aqueous HCl solutions. An increase in the transfer volume of d-xylose with increasing HCl concentrations has been explained by the stronger interactions of H + with the hydrophilic groups of d-xylose

  12. Relative nephroprotection during Escherichia coli O157:H7 infections: association with intravenous volume expansion.

    Science.gov (United States)

    Ake, Julie A; Jelacic, Srdjan; Ciol, Marcia A; Watkins, Sandra L; Murray, Karen F; Christie, Dennis L; Klein, Eileen J; Tarr, Phillip I

    2005-06-01

    who were parenteral volume expansion during E coli O157:H7 infections, well before HUS develops, is associated with attenuated renal injury failure. Parenteral hydration in children who are possibly infected with E coli O157:H7, at the time of presentation with bloody diarrhea and in advance of culture results, is a practice that can accelerate the start of volume expansion during the important pre-HUS interval. Rapid assessment of stools for E coli O157:H7 by microbiologists and reporting of presumptive positives immediately can alert practitioners that patients are at risk for developing HUS and can prompt volume expansion in children who are not already being so treated. Our data also suggest that isotonic intravenous solutions might be superior to hypotonic fluids for use as maintenance fluids. Children who are infected with E coli O157:H7 and are given intravenous volume expansion need careful monitoring. This monitoring should be even more assiduous as HUS evolves.

  13. The effect of metallic coatings and crystallinity on the volume expansion of silicon during electrochemical lithiation/delithiation

    KAUST Repository

    McDowell, Matthew T.; Woo Lee, Seok; Wang, Chongmin; Cui, Yi

    2012-01-01

    in the silicon. Tensile hoop stress causes conformal copper coatings to fracture during lithiation without undergoing bending deformation. In addition, in-situ and ex-situ observations indicate that a copper coating plays a role in suppressing volume expansion

  14. Hearing Outcomes After Stereotactic Radiosurgery for Unilateral Intracanalicular Vestibular Schwannomas: Implication of Transient Volume Expansion

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Young-Hoon [Department of Neurosurgery, Seoul National University Bundang Hospital, Seongnam-si (Korea, Republic of); Department of Neurosurgery, Seoul National University College of Medicine, Seoul (Korea, Republic of); Kim, Dong Gyu, E-mail: gknife@plaza.snu.ac.kr [Department of Neurosurgery, Seoul National University Hospital, Seoul (Korea, Republic of); Department of Neurosurgery, Seoul National University College of Medicine, Seoul (Korea, Republic of); Han, Jung Ho [Department of Neurosurgery, Seoul National University Bundang Hospital, Seongnam-si (Korea, Republic of); Department of Neurosurgery, Seoul National University College of Medicine, Seoul (Korea, Republic of); Chung, Hyun-Tai; Kim, In Kyung; Song, Sang Woo [Department of Neurosurgery, Seoul National University Hospital, Seoul (Korea, Republic of); Department of Neurosurgery, Seoul National University College of Medicine, Seoul (Korea, Republic of); Park, Jeong-Hoon [Department of Neurosurgery, Seoul National University Bundang Hospital, Seongnam-si (Korea, Republic of); Department of Neurosurgery, Seoul National University College of Medicine, Seoul (Korea, Republic of); Kim, Jin Wook; Kim, Yong Hwy; Park, Chul-Kee [Department of Neurosurgery, Seoul National University Hospital, Seoul (Korea, Republic of); Department of Neurosurgery, Seoul National University College of Medicine, Seoul (Korea, Republic of); Kim, Chae-Yong [Department of Neurosurgery, Seoul National University Bundang Hospital, Seongnam-si (Korea, Republic of); Department of Neurosurgery, Seoul National University College of Medicine, Seoul (Korea, Republic of); Paek, Sun Ha; Jung, Hee-Won [Department of Neurosurgery, Seoul National University Hospital, Seoul (Korea, Republic of); Department of Neurosurgery, Seoul National University College of Medicine, Seoul (Korea, Republic of)

    2013-01-01

    Purpose: We evaluated the prognostic factors for hearing outcomes after stereotactic radiosurgery (SRS) for unilateral sporadic intracanalicular vestibular schwannomas (IC-VSs) as a clinical homogeneous group of VSs. Methods and Materials: Sixty consecutive patients with unilateral sporadic IC-VSs, defined as tumors in the internal acoustic canal, and serviceable hearing (Gardner-Roberson grade 1 or 2) were treated with SRS as an initial treatment. The mean tumor volume was 0.34 {+-} 0.03 cm{sup 3} (range, 0.03-1.00 cm{sup 3}), and the mean marginal dose was 12.2 {+-} 0.1 Gy (range, 11.5-13.0 Gy). The median follow-up duration was 62 months (range, 36-141 months). Results: The actuarial rates of serviceable hearing preservation were 70%, 63%, and 55% at 1, 2, and 5 years after SRS, respectively. In multivariate analysis, transient volume expansion of {>=}20% from initial tumor size was a statistically significant risk factor for loss of serviceable hearing and hearing deterioration (increase of pure tone average {>=}20 dB) (odds ratio = 7.638; 95% confidence interval, 2.317-25.181; P=.001 and odds ratio = 3.507; 95% confidence interval, 1.228-10.018; P=.019, respectively). The cochlear radiation dose did not reach statistical significance. Conclusions: Transient volume expansion after SRS for VSs seems to be correlated with hearing deterioration when defined properly in a clinically homogeneous group of patients.

  15. Finite-volume cumulant expansion in QCD-colorless plasma

    Energy Technology Data Exchange (ETDEWEB)

    Ladrem, M. [Taibah University, Physics Department, Faculty of Science, Al-Madinah, Al-Munawwarah (Saudi Arabia); Physics Department, Algiers (Algeria); ENS-Vieux Kouba (Bachir El-Ibrahimi), Laboratoire de Physique et de Mathematiques Appliquees (LPMA), Algiers (Algeria); Ahmed, M.A.A. [Taibah University, Physics Department, Faculty of Science, Al-Madinah, Al-Munawwarah (Saudi Arabia); ENS-Vieux Kouba (Bachir El-Ibrahimi), Laboratoire de Physique et de Mathematiques Appliquees (LPMA), Algiers (Algeria); Taiz University in Turba, Physics Department, Taiz (Yemen); Alfull, Z.Z. [Taibah University, Physics Department, Faculty of Science, Al-Madinah, Al-Munawwarah (Saudi Arabia); Cherif, S. [ENS-Vieux Kouba (Bachir El-Ibrahimi), Laboratoire de Physique et de Mathematiques Appliquees (LPMA), Algiers (Algeria); Ghardaia University, Sciences and Technologies Department, Ghardaia (Algeria)

    2015-09-15

    Due to the finite-size effects, the localization of the phase transition in finite systems and the determination of its order, become an extremely difficult task, even in the simplest known cases. In order to identify and locate the finite-volume transition point T{sub 0}(V) of the QCD deconfinement phase transition to a colorless QGP, we have developed a new approach using the finite-size cumulant expansion of the order parameter and the L{sub mn}-method. The first six cumulants C{sub 1,2,3,4,5,6} with the corresponding under-normalized ratios (skewness Σ, kurtosis κ, pentosis Π{sub ±}, and hexosis H{sub 1,2,3}) and three unnormalized combinations of them, (O = σ{sup 2}κΣ{sup -1},U = σ{sup -2}Σ{sup -1},N = σ{sup 2}κ) are calculated and studied as functions of (T, V). A new approach, unifying in a clear and consistent way the definitions of cumulant ratios, is proposed.Anumerical FSS analysis of the obtained results has allowed us to locate accurately the finite-volume transition point. The extracted transition temperature value T{sub 0}(V) agrees with that expected T{sub 0}{sup N}(V) from the order parameter and the thermal susceptibility χ{sub T} (T, V), according to the standard procedure of localization to within about 2%. In addition to this, a very good correlation factor is obtained proving the validity of our cumulants method. The agreement of our results with those obtained by means of other models is remarkable. (orig.)

  16. Glue embolization of the giant aneurysm by reducing thrombosis-induced volume expansion effect

    Energy Technology Data Exchange (ETDEWEB)

    Yeom, Yoo Kyung; Suh, Dae Chul [Dept. of Radiology and Research Institute of Radiology, University of Ulsan College of Medicine, Asan Medical Center, Seoul (Korea, Republic of)

    2015-04-15

    A giant aneurysm due to a large intra-aneurysmal volume can be complicated by a delayed massive volume expansion caused by thrombus formation. To prevent such a severe mass effect, we obliterated the aneurysmal lumen by gluing and prevented further development of thrombosis. A 52-year-old female with a giant aneurysm at the cavernous segment of the internal carotid artery presented with tinnitus and intermittent diplopia. After confirming with a negative occlusion test, the right internal carotid artery was trapped by coiling and with further obliteration of the aneurysmal lumen by gluing. She developed a mild diplopia after the procedure and recovered without any deficit. The magnetic resonance angiography showed a stable occlusion of the aneurysm and good collateral filling of the cerebral vessel 15 months later.

  17. Glue embolization of the giant aneurysm by reducing thrombosis-induced volume expansion effect

    International Nuclear Information System (INIS)

    Yeom, Yoo Kyung; Suh, Dae Chul

    2015-01-01

    A giant aneurysm due to a large intra-aneurysmal volume can be complicated by a delayed massive volume expansion caused by thrombus formation. To prevent such a severe mass effect, we obliterated the aneurysmal lumen by gluing and prevented further development of thrombosis. A 52-year-old female with a giant aneurysm at the cavernous segment of the internal carotid artery presented with tinnitus and intermittent diplopia. After confirming with a negative occlusion test, the right internal carotid artery was trapped by coiling and with further obliteration of the aneurysmal lumen by gluing. She developed a mild diplopia after the procedure and recovered without any deficit. The magnetic resonance angiography showed a stable occlusion of the aneurysm and good collateral filling of the cerebral vessel 15 months later.

  18. Hearing Outcomes After Stereotactic Radiosurgery for Unilateral Intracanalicular Vestibular Schwannomas: Implication of Transient Volume Expansion

    International Nuclear Information System (INIS)

    Kim, Young-Hoon; Kim, Dong Gyu; Han, Jung Ho; Chung, Hyun-Tai; Kim, In Kyung; Song, Sang Woo; Park, Jeong-Hoon; Kim, Jin Wook; Kim, Yong Hwy; Park, Chul-Kee; Kim, Chae-Yong; Paek, Sun Ha; Jung, Hee-Won

    2013-01-01

    Purpose: We evaluated the prognostic factors for hearing outcomes after stereotactic radiosurgery (SRS) for unilateral sporadic intracanalicular vestibular schwannomas (IC-VSs) as a clinical homogeneous group of VSs. Methods and Materials: Sixty consecutive patients with unilateral sporadic IC-VSs, defined as tumors in the internal acoustic canal, and serviceable hearing (Gardner-Roberson grade 1 or 2) were treated with SRS as an initial treatment. The mean tumor volume was 0.34 ± 0.03 cm 3 (range, 0.03-1.00 cm 3 ), and the mean marginal dose was 12.2 ± 0.1 Gy (range, 11.5-13.0 Gy). The median follow-up duration was 62 months (range, 36-141 months). Results: The actuarial rates of serviceable hearing preservation were 70%, 63%, and 55% at 1, 2, and 5 years after SRS, respectively. In multivariate analysis, transient volume expansion of ≥20% from initial tumor size was a statistically significant risk factor for loss of serviceable hearing and hearing deterioration (increase of pure tone average ≥20 dB) (odds ratio = 7.638; 95% confidence interval, 2.317-25.181; P=.001 and odds ratio = 3.507; 95% confidence interval, 1.228-10.018; P=.019, respectively). The cochlear radiation dose did not reach statistical significance. Conclusions: Transient volume expansion after SRS for VSs seems to be correlated with hearing deterioration when defined properly in a clinically homogeneous group of patients.

  19. A model to estimate volume change due to radiolytic gas bubbles and thermal expansion in solution reactors

    International Nuclear Information System (INIS)

    Souto, F.J.; Heger, A.S.

    2001-01-01

    To investigate the effects of radiolytic gas bubbles and thermal expansion on the steady-state operation of solution reactors at the power level required for the production of medical isotopes, a calculational model has been developed. To validate this model, including its principal hypotheses, specific experiments at the Los Alamos National Laboratory SHEBA uranyl fluoride solution reactor were conducted. The following sections describe radiolytic gas generation in solution reactors, the equations to estimate the fuel solution volume change due to radiolytic gas bubbles and thermal expansion, the experiments conducted at SHEBA, and the comparison of experimental results and model calculations. (author)

  20. Aileler, Öğretmenler ve Dil ve Konuşma Terapistlerinin Çocuklardaki Dil ve Konuşma Bozukluklarına Yönelik Tutum ve Bilgilerinin Değerlendirilmesi

    Directory of Open Access Journals (Sweden)

    Bülent TOĞRAM

    2015-12-01

    Full Text Available Çocuklardaki iletişim sorunları aile bildirimleri, öğretmen raporları ve dil ve konuşma terapistleri (DKT tarafından yapılan değerlendirmeler ile saptanmaktadır. Dil ve konuşma bozukluklarının önlenmesi ve terapisinde işbirliği içinde bulunmaları gereken bu üçlü grubun konuya ilişkin görüş ve tutumları alanyazında önemli bulunmaktadır. Bu çalışmanın amacı, ebeveynlerin, öğretmenlerin ve DKT’lerin dil ve konuşma bozuklukları alanındaki sorumluluk ve rollerini nasıl algıladıklarını, dil ve konuşma bozukluğu olan çocuğun akademik ve sosyal başarısına yönelik tutumlarını, dil ve konuşma bozukluklarının nedenleri ve terapisine yönelik düşüncelerini betimlemektir. Çalışmaya 37 aile bireyi, 46 öğretmen ve 35 DKT katılmıştır. Anket yoluyla elde edilen veriler her grubun konuya ilişkin bilgisini ortaya koymak için karşılaştırılmıştır. Dil ve konuşma bozukluğu olan çocukların akademik/sosyal başarılarına yönelik tutumlarında diğer katılımcı gruplara göre öğretmenlerin, çocukların terapi gereksinimlerine yönelik tutumlarında ise ailelerin daha kararsız tutumlar geliştirdikleri dikkat çekmektedir.Dil ve konuşma bozukluklarının nedenleri ve terapi eksikliklerine yönelik bilgilerinde grupların öncelikli sıralamalarının farklılaştığı görülmüştür

  1. Expansion of the cathode spot and generation of shock waves in the plasma of a volume discharge in atmospheric-pressure helium

    International Nuclear Information System (INIS)

    Omarov, O. A.; Kurbanismailov, V. S.; Arslanbekov, M. A.; Gadzhiev, M. Kh.; Ragimkhanov, G. B.; Al-Shatravi, Ali J. G.

    2012-01-01

    The expansion of the cathode spot and the generation of shock waves during the formation and development of a pulsed volume discharge in atmospheric-pressure helium were studied by analyzing the emission spectra of the cathode plasma and the spatiotemporal behavior of the plasma glow. The transition of a diffuse volume discharge in a centimeter-long gap into a high-current diffuse mode when the gas pressure increased from 1 to 5 atm and the applied voltage rose from the statistical breakdown voltage to a 100% overvoltage was investigated. Analytical expressions for the radius of the cathode spot and its expansion velocity obtained in the framework of a spherically symmetric model agree satisfactorily with the experimental data.

  2. The effect of metallic coatings and crystallinity on the volume expansion of silicon during electrochemical lithiation/delithiation

    KAUST Repository

    McDowell, Matthew T.

    2012-05-01

    Applying surface coatings to alloying anodes for Li-ion batteries can improve rate capability and cycle life, but it is unclear how this second phase affects mechanical deformation during electrochemical reaction. Here, in-situ transmission electron microscopy is employed to investigate the electrochemical lithiation and delithiation of silicon nanowires (NWs) with copper coatings. When copper is coated on only one sidewall, the NW bilayer structure bends during delithiation due to length changes in the silicon. Tensile hoop stress causes conformal copper coatings to fracture during lithiation without undergoing bending deformation. In addition, in-situ and ex-situ observations indicate that a copper coating plays a role in suppressing volume expansion during lithiation. Finally, the deformation characteristics and dimensional changes of amorphous, polycrystalline, and single-crystalline silicon are compared and related to observed electrochemical behavior. This study reveals important aspects of the deformation process of silicon anodes, and the results suggest that metallic coatings can be used to improve rate behavior and to manage or direct volume expansion in optimized silicon anode frameworks. © 2012 Elsevier Ltd.

  3. VE of construction industry

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1987-10-15

    This book gives descriptions of basic of VE of construction industry including doing away with mannerism, necessity of cost reduction, management method of cost reduction, thinking of idea, target of VE, starting VE activity, technical method of VE of construction industry such as thinking of idea with brainstorming, function trade method, new brainstorming, MM method, morphology analysis and lateral thinking, cases of VE of construction industry.

  4. VE of construction industry

    International Nuclear Information System (INIS)

    1987-10-01

    This book gives descriptions of basic of VE of construction industry including doing away with mannerism, necessity of cost reduction, management method of cost reduction, thinking of idea, target of VE, starting VE activity, technical method of VE of construction industry such as thinking of idea with brainstorming, function trade method, new brainstorming, MM method, morphology analysis and lateral thinking, cases of VE of construction industry.

  5. The VE/CAD synergism

    International Nuclear Information System (INIS)

    Sperling, R.B.

    1993-01-01

    Value Engineering (VE) and Computer-Aided Design (CAD) can be used synergistically to reduce costs and improve facilities designs. The cost and schedule impacts of implementing alternative design ideas developed by VE teams can be greatly reduced when the drawings have been produced with interactive CAD systems. To better understand the interrelationship between VE and CAD, the fundamentals of the VE process are explained; and example of a VE proposal is described and the way CAD drawings facilitated its implementation is illustrated

  6. Colossal negative thermal expansion in reduced layered ruthenate.

    Science.gov (United States)

    Takenaka, Koshi; Okamoto, Yoshihiko; Shinoda, Tsubasa; Katayama, Naoyuki; Sakai, Yuki

    2017-01-10

    Large negative thermal expansion (NTE) has been discovered during the last decade in materials of various kinds, particularly materials associated with a magnetic, ferroelectric or charge-transfer phase transition. Such NTE materials have attracted considerable attention for use as thermal-expansion compensators. Here, we report the discovery of giant NTE for reduced layered ruthenate. The total volume change related to NTE reaches 6.7% in dilatometry, a value twice as large as the largest volume change reported to date. We observed a giant negative coefficient of linear thermal expansion α=-115 × 10 -6  K -1 over 200 K interval below 345 K. This dilatometric NTE is too large to be attributable to the crystallographic unit-cell volume variation with temperature. The highly anisotropic thermal expansion of the crystal grains might underlie giant bulk NTE via microstructural effects consuming open spaces in the sintered body on heating.

  7. CELESTINA: CALISTO VE MELİBEA’NIN TRAJIKOMEDYASI’NDA ORTAÇAĞ VE RÖNESANS ARASINDA KALMIŞ BİREY VE KADIN

    Directory of Open Access Journals (Sweden)

    Nur Gülümser İLKER

    2017-06-01

    Full Text Available İspanyol Edebiyatının Ortaçağ toplumu ve bireyi arasındaki çatışmayı ele almasıyla en önemli eserlerinden biri olan Celestina: Calisto ve Melibea’nın Trajikomedyası, Rönesans’a dönmüş yüzüyle de önem kazanmaktadır. Yazar Fernando de Rojas’ın ustalıkla ve incelikle yarattığı karakterler vasıtasıyla, dönemin birey algısına odaklanırken, toplumun normlarının bireyler üzerindeki üstünlüğüne tanık oluruz. Aynı zamanda kadına karşı olan bakış açısının da vurgulandığı eserde, evrensel konular gün yüzüne çıkarken, insan, doğasıyla ve içgüdüleriyle işlenerek okuyucuya sunulur. Eserde genç, tutkularının kölesi olmuş Calisto ve saf, geleneklerine bağlı Melibea’nın aşkıyla ve de yaşlı büyücü Celestina’nın tamahkârlığıyla insani duyguların aşırıya kaçması eleştirilir. Topluma uygun olmayan eylemler sonucunda cezalandırılan karakterleriyle eser, didaktik bir metin olma özelliği taşımaktadır. Çalışmanın konusu olarak sözü geçen eserdeki birey ve kadın, Ortaçağ ve Rönesans arasında kalmış olarak ele alınacak ve incelenecektir.

  8. PREPD O and VE remote handling system

    International Nuclear Information System (INIS)

    Theil, T.N.

    1985-01-01

    The Process Experimental Pilot Plant (PREPP) at the Idaho National Engineering Laboratory is designed for volume reduction and packaging of transuranic (TRU) waste. The PREPP opening and verification enclosure (O and VE) remote handling system, within that facility, is designed to provide examination of the contents of various TRU waste storage containers. This remote handling system will provide the means of performing a hazardous operation that is currently performed manually. The TeleRobot to be used in this system is a concept that will incorporate and develop man in the loop operation (manual mode), standardized automatic sequencing of end effector tools, increased payload and reach over currently available computer-controlled robots, and remote handling of a hazardous waste operation. The system is designed within limited space constraints and an operation that was originally planned, and is currently being manually performed at other plants. The PREPP O and VE remote handling system design incorporates advancing technology to improve the working environment in the nuclear field

  9. Hematoma Expansion Following Acute Intracerebral Hemorrhage

    Science.gov (United States)

    Brouwers, H. Bart; Greenberg, Steven M.

    2013-01-01

    Intracerebral hemorrhage, the most devastating form of stroke, has no specific therapy proven to improve outcome by randomized controlled trial. Location and baseline hematoma volume are strong predictors of mortality, but are non-modifiable by the time of diagnosis. Expansion of the initial hematoma is a further marker of poor prognosis that may be at least partly preventable. Several risk factors for hematoma expansion have been identified, including baseline ICH volume, early presentation after symptom onset, anticoagulation, and the CT angiography spot sign. Although the biological mechanisms of hematoma expansion remain unclear, accumulating evidence supports a model of ongoing secondary bleeding from ruptured adjacent vessels surrounding the initial bleeding site. Several large clinical trials testing therapies aimed at preventing hematoma expansion are in progress, including aggressive blood pressure reduction, treatment with recombinant factor VIIa guided by CT angiography findings, and surgical intervention for superficial hematomas without intraventricular extension. Hematoma expansion is so far the only marker of outcome that is amenable to treatment and thus a potentially important therapeutic target. PMID:23466430

  10. Density-functional expansion methods: Grand challenges.

    Science.gov (United States)

    Giese, Timothy J; York, Darrin M

    2012-03-01

    We discuss the source of errors in semiempirical density functional expansion (VE) methods. In particular, we show that VE methods are capable of well-reproducing their standard Kohn-Sham density functional method counterparts, but suffer from large errors upon using one or more of these approximations: the limited size of the atomic orbital basis, the Slater monopole auxiliary basis description of the response density, and the one- and two-body treatment of the core-Hamiltonian matrix elements. In the process of discussing these approximations and highlighting their symptoms, we introduce a new model that supplements the second-order density-functional tight-binding model with a self-consistent charge-dependent chemical potential equalization correction; we review our recently reported method for generalizing the auxiliary basis description of the atomic orbital response density; and we decompose the first-order potential into a summation of additive atomic components and many-body corrections, and from this examination, we provide new insights and preliminary results that motivate and inspire new approximate treatments of the core-Hamiltonian.

  11. Analysis of thermal expansivity of solids at extreme compression

    Directory of Open Access Journals (Sweden)

    J. Shanker

    2008-12-01

    Full Text Available Thermodynamics of solids in the limit of infinite pressure formulated by Stacey reveals that the thermal expansivity (alpha of solids tends to zero at infinite pressure. The earlier models for the volume dependence of thermal expansivity do not satisfy the infinite pressure behaviour of thermal expansivity. The expressions for the volume dependence of the isothermal Anderson- Grüneisen parameter (delta T considered in the derivation of earlier formulations for alpha (V have been found to be inadequate. A formulation for the volume dependence of delta T is presented here which is similar to the model due to Burakovsky and Preston for the volume dependence of the Grüneisen parameter. The new formulation for alpha (V reveals that delta T infinity must be greater than zero for satisfying the thermodynamic result according to which alpha tends to zero at infinite pressure. It is found that our model fits well the experimental data on thermal expansivity alpha (V for hcp iron corresponding to a wide range of pressures (0-360 GPa.

  12. Low thermal expansion glass ceramics

    CERN Document Server

    1995-01-01

    This book is one of a series reporting on international research and development activities conducted by the Schott group of companies With the series, Schott aims to provide an overview of its activities for scientists, engineers, and managers from all branches of industry worldwide where glasses and glass ceramics are of interest Each volume begins with a chapter providing a general idea of the current problems, results, and trends relating to the subjects treated This volume describes the fundamental principles, the manufacturing process, and applications of low thermal expansion glass ceramics The composition, structure, and stability of polycrystalline materials having a low thermal expansion are described, and it is shown how low thermal expansion glass ceramics can be manufactured from appropriately chosen glass compositions Examples illustrate the formation of this type of glass ceramic by utilizing normal production processes together with controlled crystallization Thus glass ceramics with thermal c...

  13. Stochastic model prediction of the Kovacs' ``expansion gap'' effect for volume relaxation in glassy polymers

    Science.gov (United States)

    Medvedev, Grigori; Caruthers, James

    2015-03-01

    The classic series of experiments by A. Kovacs on volume relaxation following temperature jumps for poly(vinyl acetate), PVAc, in the Tg region revealed the richness and complexity of the viscoelastic behavior of glassy materials. Over the years no theoretical model has been able to predict all the features of the Kovacs data, where the so-called ``expansion gap'' effect proved to be particularly challenging. Specifically, for a series of up-jump experiments with different initial temperatures, Ti, but with the same final temperature, as the relaxation approaches equilibrium it would be expected that the effective relaxation time would be the same regardless of Ti; however, Kovacs observed that the dependence on Ti persisted seemingly all the way to equilibrium. In this communication we will show that a recently developed Stochastic Constitutive Model (SCM) that explicitly acknowledges the nano-scale dynamic heterogeneity of glasses can capture the ``expansion gap'' as well as the rest of the Kovacs data set for PVAc. It will be shown that the success of the SCM is due to its inherent thermo-rheological complexity.

  14. Hole-expansion formability of dual-phase steels using representative volume element approach with boundary-smoothing technique

    International Nuclear Information System (INIS)

    Kim, Ji Hoon; Lee, M.G.; Kim, D.; Matlock, D.K.; Wagoner, R.H.

    2010-01-01

    Research highlights: → Robust microstructure-based FE mesh generation technique was developed. → Local deformation behavior near phase boundaries could be quantitatively understood. → Macroscopic failure could be connected to microscopic deformation behavior of multi-phase steel. - Abstract: A qualitative analysis was carried out on the formability of dual-phase (DP) steels by introducing a realistic microstructure-based finite element approach. The present microstructure-based model was constructed using a mesh generation process with a boundary-smoothing algorithm after proper image processing. The developed model was applied to hole-expansion formability tests for DP steel sheets having different volume fractions and morphological features. On the basis of the microstructural inhomogeneity observed in the scanning electron micrographs of the DP steel sheets, it was inferred that the localized plastic deformation in the ferritic phase might be closely related to the macroscopic formability of DP steel. The experimentally observed difference between the hole-expansion formability of two different microstructures was reasonably explained by using the present finite element model.

  15. Kayalarda Delme ve Patlama

    OpenAIRE

    ÖZDOĞAN, Metin

    1986-01-01

    Bu makalede açık işletmecilikte delme ve patlatma işlemlerinin günümüzdeki kuramsal ve pratik durumu sunulmaktadır. Kayanın mekanik olarak parçalanması bölümünde vurmalı ve dönmeli delme dizgeleri verilmiştir. Kayanın devinik olarak parçalanması başlığı altında ise patlatma incelenmiş ve patlatma işlemini etkileyen etmenler, patlatma kuşakları, yansıma kuramı, krater deneylerine değinilmiştir

  16. Monte Carlo Finite Volume Element Methods for the Convection-Diffusion Equation with a Random Diffusion Coefficient

    Directory of Open Access Journals (Sweden)

    Qian Zhang

    2014-01-01

    Full Text Available The paper presents a framework for the construction of Monte Carlo finite volume element method (MCFVEM for the convection-diffusion equation with a random diffusion coefficient, which is described as a random field. We first approximate the continuous stochastic field by a finite number of random variables via the Karhunen-Loève expansion and transform the initial stochastic problem into a deterministic one with a parameter in high dimensions. Then we generate independent identically distributed approximations of the solution by sampling the coefficient of the equation and employing finite volume element variational formulation. Finally the Monte Carlo (MC method is used to compute corresponding sample averages. Statistic error is estimated analytically and experimentally. A quasi-Monte Carlo (QMC technique with Sobol sequences is also used to accelerate convergence, and experiments indicate that it can improve the efficiency of the Monte Carlo method.

  17. Van Otlu Peynirinin Yapılışı ve Mikrobiyolojik, Fiziksel ve Kimyasal Nitelikleri

    Directory of Open Access Journals (Sweden)

    Ahmet Kurt

    2015-02-01

    Full Text Available Bu araştırmada 10 adet taze Van Otlu peyniri örneklerine; mikrobiyolojik, fiziksel ve kimyasal analizler uygulanmıştır. Peynir teknolojisinde, sağlık, teknik ve ekonomik yönden önemli olan toplam koliform, süt asidi, lipolitik ve proteolitik mikroorganizmalarla maya ve küflerin sayısal değerleri yanında rutubet, yağ, yağsız kurumadde, kurumaddede yağ, protein, suda eriyen protein, kül, tuz, saf kül, kurumaddede tuz ve % asitlik oranları, peynir örneklerinde ayrı ayrı saptanmıştır. Elde edilen sonuçlara göre peynir yapımı çok dağınık ve ilkel karakter arz etmektedir. Peynirlerin yapımındaki farklı uygulamalar, teknik bilgi ve yöntem noksanlığı yüzünden, gerek mikrobiyolojik analiz ve gerekse fiziksel ve kimyasal analiz sonuçları örnekten örneğe önemli fraklılıklar göstermiştir. Peynir örneklerinde saptanan Koliform organizma sayıları, hem sağlık yönünden hem de peynirlerin olgunlaşmalarında sorunlara neden olabilecek düzeydedir.

  18. VE for innovative cost reduction

    International Nuclear Information System (INIS)

    1987-07-01

    This book deals with goal of value engineering characteristic of development details and development background of VE, the reason that VE is well appreciated, steps of VE process such as collection of basic information, selection of theme, organization of optimum team, item plan, function design, estimation and explanation of search result of values, item design, practical plan of innovative issue, VE reference data, and development of creative power.

  19. The impact of maternal plasma volume expansion and antihypertensive treatment with intravenous dihydralazine on fetal and maternal hemodynamics during pre-eclampsia: a clinical, echo-Doppler and viscometric study.

    NARCIS (Netherlands)

    Boito, S.M.; Struijk, P.C.; Pop, G.A.M.; Visser, W. de; Steegers, E.A.P.; Wladimiroff, J.W.

    2004-01-01

    OBJECTIVES: To establish the effects of plasma volume expansion (PVE) followed by intravenous dihydralazine (DH) administration on maternal whole blood viscosity (WBV) and hematocrit, uteroplacental and fetoplacental downstream impedance and umbilical venous (UV) volume flow in pre-eclampsia.

  20. Functional Analysis of the Tomato Immune Receptor Ve1 through Domain Swaps with Its Non-Functional Homolog Ve2

    Science.gov (United States)

    Rovenich, Hanna; Song, Yin; Liebrand, Thomas W. H.; Masini, Laura; van den Berg, Grardy C. M.; Joosten, Matthieu H. A. J.; Thomma, Bart P. H. J.

    2014-01-01

    Resistance in tomato against race 1 strains of the fungal vascular wilt pathogens Verticillium dahliae and V. albo-atrum is mediated by the Ve locus. This locus comprises two closely linked inversely oriented genes, Ve1 and Ve2, which encode cell surface receptors of the extracellular leucine-rich repeat receptor-like protein (eLRR-RLP) type. While Ve1 mediates Verticillium resistance through monitoring the presence of the recently identified V. dahliae Ave1 effector, no functionality for Ve2 has been demonstrated in tomato. Ve1 and Ve2 contain 37 eLRRs and share 84% amino acid identity, facilitating investigation of Ve protein functionality through domain swapping. In this study it is shown that Ve chimeras in which the first thirty eLRRs of Ve1 were replaced by those of Ve2 remain able to induce HR and activate Verticillium resistance, and that deletion of these thirty eLRRs from Ve1 resulted in loss of functionality. Also the region between eLRR30 and eLRR35 is required for Ve1-mediated resistance, and cannot be replaced by the region between eLRR30 and eLRR35 of Ve2. We furthermore show that the cytoplasmic tail of Ve1 is required for functionality, as truncation of this tail results in loss of functionality. Moreover, the C-terminus of Ve2 fails to activate immune signaling as chimeras containing the C-terminus of Ve2 do not provide Verticillium resistance. Furthermore, Ve1 was found to interact through its C-terminus with the eLRR-containing receptor-like kinase (eLRR-RLK) interactor SOBIR1 that was recently identified as an interactor of eLRR-RLP (immune) receptors. Intriguingly, also Ve2 was found to interact with SOBIR1. PMID:24505431

  1. Thermal expansion and phase transitions of α-AlF{sub 3}

    Energy Technology Data Exchange (ETDEWEB)

    Morelock, Cody R.; Hancock, Justin C. [School of Chemistry and Biochemistry, Georgia Institute of Technology, Atlanta, GA 30332-0400 (United States); Wilkinson, Angus P., E-mail: angus.wilkinson@chemistry.gatech.edu [School of Chemistry and Biochemistry, Georgia Institute of Technology, Atlanta, GA 30332-0400 (United States); School of Materials Science and Engineering, Georgia Institute of Technology, Atlanta, GA 30332-0245 (United States)

    2014-11-15

    ReO{sub 3}-type materials are of interest for their potential low or negative thermal expansion. Many metal trifluorides MF{sub 3} adopt the cubic form of this structure at elevated temperatures, which rhombohedrally distorts upon cooling. The rhombohedral form displays strong positive volume thermal expansion, but cubic MF{sub 3} display much lower and sometimes negative thermal expansion. The expansion behavior of α-AlF{sub 3} was characterized via synchrotron powder diffraction between 323 and 1177 K. α-AlF{sub 3} is rhombohedral at ambient conditions and displays strongly anisotropic thermal expansion. The volume coefficient of thermal expansion (CTE), α{sub V}, at 500 K is ∼86 ppm K{sup −1}, but the linear CTE along the c-axis, α{sub c}, is close to zero. α-AlF{sub 3} becomes cubic on heating to ∼713 K and continues to show positive thermal expansion above the phase transition (α{sub V}(900 K) ∼25 ppm K{sup −1}). - Graphical abstract: α-AlF{sub 3} has a rhombohedrally distorted ReO{sub 3}-type structure at ambient conditions and displays strongly positive volume thermal expansion that is highly anisotropic; the material becomes cubic on heating above ∼713 K and continues to show positive thermal expansion. - Highlights: • ReO{sub 3}-type α-AlF{sub 3} displays strongly anisotropic thermal expansion below 713 K. • α-AlF{sub 3} is cubic above 713 K and maintains positive (isotropic) thermal expansion. • The volume CTE changes from ∼86 to ∼25 ppm K{sup −1} on heating from 500 to 900 K. • The PTE of cubic α-AlF{sub 3} may be due to the presence of local octahedral tilts.

  2. Thermal expansion of L-ascorbic acid

    Science.gov (United States)

    Nicolaï, B.; Barrio, M.; Tamarit, J.-Ll.; Céolin, R.; Rietveld, I. B.

    2017-04-01

    The specific volume of vitamin C has been investigated by X-ray powder diffraction as a function of temperature from 110 K up to complete degradation around 440 K. Its thermal expansion is relatively small in comparison with other organic compounds with an expansivity α v of 1.2(3) × 10-4 K-1. The structure consists of strongly bound molecules in the ac plane through a dense network of hydrogen bonds. The thermal expansion is anisotropic. Along the b axis, the expansion has most leeway and is about 10 times larger than in the other directions.

  3. Effect of pyloroplasty and fundectomy on the delay of gastric emptying and gastrointestinal transit of liquid elicited by acute blood volume expansion in awake rats

    Directory of Open Access Journals (Sweden)

    M.C.V. Rêgo

    1998-03-01

    Full Text Available We evaluated the effects of fundectomy and pyloroplasty on the delay of gastric emptying (GE and gastrointestinal (GI transit of liquid due to blood volume (BV expansion in awake rats. Male Wistar rats (N = 76, 180-250 g were first submitted to fundectomy (N = 26, Heinecke-Mikulicz pyloroplasty (N = 25 or SHAM laparotomy (N = 25. After 6 days, the left external jugular vein was cannulated and the animals were fasted for 24 h with water ad libitum. The test meal was administered intragastrically (1.5 ml of a phenol red solution, 0.5 mg/ml in 5% glucose to normovolemic control animals and to animals submitted to BV expansion (Ringer-bicarbonate, iv infusion, 1 ml/min, volume up to 5% body weight. BV expansion decreased GE and GI transit rates in SHAM laparotomized animals by 52 and 35.9% (P<0.05. Fundectomy increased GE and GI transit rates by 61.1 and 67.7% (P<0.05 and prevented the effect of expansion on GE but not on GI transit (13.9% reduction, P<0.05. Pyloroplasty also increased GE and GI transit rates by 33.9 and 44.8% (P<0.05 but did not prevent the effect of expansion on GE or GI transit (50.7 and 21.1% reduction, P<0.05. Subdiaphragmatic vagotomy blocked the effect of expansion on GE and GI transit in both SHAM laparotomized animals and animals submitted to pyloroplasty. In conclusion 1 the proximal stomach is involved in the GE delay due to BV expansion but is not essential for the establishment of a delay in GI transit, which suggests the activation of intestinal resistances, 2 pyloric modulation was not apparent, and 3 vagal pathways are involved

  4. Apparent molar volumes, isobaric expansion coefficients, and isentropic compressibilities, and their H/D isotope effects for some aqueous carbohydrate solutions

    International Nuclear Information System (INIS)

    Bernal, P.J.; Van Hook, W.A.

    1986-01-01

    The molar volumes, isobaric expansion coefficients, and isentropic compressibilities of solutions of a number of carbohydrates and their deuterated isomers were determined in H 2 O and D 2 O between 288.15 and 328.15 K and over a wide range of solute-to-solvent mole ratios. The results are discussed in terms of the specific hydration model. (author)

  5. Hücre siklusu ve kanser

    OpenAIRE

    Cabadak, Hülya

    2008-01-01

    Hücre çogalması ve hücre siklusunun ilerlemesi büyümenin kontrolünde rolü olan genlerin ekspresyonu ile baglantılıdır. Ökaryot hücre siklusuM(mitoz) G , S ve G fazlarından olusmaktadır. Bu süreçte hücre uyarımı ve büyüme meydana gelir veya hücre G fazında durmaktadır. Hücre siklusunda G -S geçisinde, G -Mgeçisinde ve metafaz-anafaz geçisinde kontrol noktaları bulunmaktadır. Hücre siklusu siklin bagımlı kinazlar (cdk, katalitik altbirim) ve siklin (cyc, düzenleyici altbirim) tarafı...

  6. Effects of emergency department expansion on emergency department patient flow.

    Science.gov (United States)

    Mumma, Bryn E; McCue, James Y; Li, Chin-Shang; Holmes, James F

    2014-05-01

    Emergency department (ED) crowding is an increasing problem associated with adverse patient outcomes. ED expansion is one method advocated to reduce ED crowding. The objective of this analysis was to determine the effect of ED expansion on measures of ED crowding. This was a retrospective study using administrative data from two 11-month periods before and after the expansion of an ED from 33 to 53 adult beds in an academic medical center. ED volume, staffing, and hospital admission and occupancy data were obtained either from the electronic health record (EHR) or from administrative records. The primary outcome was the rate of patients who left without being treated (LWBT), and the secondary outcome was total ED boarding time for admitted patients. A multivariable robust linear regression model was used to determine whether ED expansion was associated with the outcome measures. The mean (±SD) daily adult volume was 128 (±14) patients before expansion and 145 (±17) patients after. The percentage of patients who LWBT was unchanged: 9.0% before expansion versus 8.3% after expansion (difference = 0.6%, 95% confidence interval [CI] = -0.16% to 1.4%). Total ED boarding time increased from 160 to 180 hours/day (difference = 20 hours, 95% CI = 8 to 32 hours). After daily ED volume, low-acuity area volume, daily wait time, daily boarding hours, and nurse staffing were adjusted for, the percentage of patients who LWBT was not independently associated with ED expansion (p = 0.053). After ED admissions, ED intensive care unit (ICU) admissions, elective surgical admissions, hospital occupancy rate, ICU occupancy rate, and number of operational ICU beds were adjusted for, the increase in ED boarding hours was independently associated with the ED expansion (p = 0.005). An increase in ED bed capacity was associated with no significant change in the percentage of patients who LWBT, but had an unintended consequence of an increase in ED boarding hours. ED expansion alone does

  7. Scoping calculation of nuclides migration in engineering barrier system for effect of volume expansion due to overpack corrosion and intrusion of the buffer material

    International Nuclear Information System (INIS)

    Yoshita, Takashi; Ishihara, Yoshinao; Ishiguro, Katsuhiko; Ohi, Takao; Nakajima, Kunihiko

    1999-11-01

    Corrosion of the carbon steel overpack leads to a volume expansion since the specific gravity of corrosion products is smaller than carbon steel. The buffer material is compressed due to the corrosive swelling, reducing its thickness and porosity. On the other hand, buffer material may be extruded into fractures of the surrounding rock and this may lead to a deterioration of the planned functions of the buffer, including retardation of nuclides migration and colloid filtration. In this study, the sensitivity analyses for the effect of volume expansion and intrusion of the buffer material on nuclide migration in the engineering barrier system are carried out. The sensitivity analyses were performed on the decrease in the thickness of the buffer material in the radial direction caused by the corrosive swelling, and the change in the porosity and dry density of the buffer caused by both compacting due to corrosive swelling and intrusion of buffer material. As results, it was found the maximum release rates of relatively shorter half-life nuclides from the outside of the buffer material decreased for taking into account of a volume expansion due to overpack corrosion. On the other hand, the maximum release rates increased when the intrusion of buffer material was also taking into account. It was, however, the maximum release rates of longer half-life nuclides, such as Cs-137 and Np-237, were insensitive to the change of buffer material thickness, and porosity and dry density of buffer. (author)

  8. The Thermal Expansion Of Feldspars

    Science.gov (United States)

    Hovis, G. L.; Medford, A.; Conlon, M.

    2009-12-01

    Hovis and others (1) investigated the thermal expansion of natural and synthetic AlSi3 feldspars and demonstrated that the coefficient of thermal expansion (α) decreases significantly, and linearly, with increasing room-temperature volume (VRT). In all such feldspars, therefore, chemical expansion limits thermal expansion. The scope of this work now has been broadened to include plagioclase and Ba-K feldspar crystalline solutions. X-ray powder diffraction data have been collected between room temperature and 925 °C on six plagioclase specimens ranging in composition from anorthite to oligoclase. When combined with thermal expansion data for albite (2,3,4) a steep linear trend of α as a function of VRT emerges, reflecting how small changes in composition dramatically affect expansion behavior. The thermal expansion data for five synthetic Ba-K feldspars ranging in composition from 20 to 100 mole percent celsian, combined with data for pure K-feldspar (3,4), show α-VRT relationships similar in nature to the plagioclase series, but with a slope and intercept different from the latter. Taken as a group all Al2Si2 feldspars, including anorthite and celsian from the present study along with Sr- (5) and Pb-feldspar (6) from other workers, show very limited thermal expansion that, unlike AlSi3 feldspars, has little dependence on the divalent-ion (or M-) site occupant. This apparently is due to the necessitated alternation of Al and Si in the tetrahedral sites of these minerals (7), which in turn locks the tetrahedral framework and makes the M-site occupant nearly irrelevant to expansion behavior. Indeed, in feldspar series with coupled chemical substitution it is the change away from a 1:1 Al:Si ratio that gives feldspars greater freedom to expand. Overall, the relationships among α, chemical composition, and room-temperature volume provide useful predictive tools for estimating feldspar thermal expansion and give insight into the controls of expansion behavior in

  9. Excess Molar Volume of Binary Mixtures of Methylheptenone+Alkanols at 298.15 K

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    Excess molar volume(VE) data on binary liquid mixtures of methylheptenone (MHO) with methanol, ethanol, n-propanol or n-butanol have been determined from the density measurements at 298.15 K and atmospheric pressure. The values of VE in all the systems over the entire composition range are quantified by the Redlich-Kister equation. The effects of the chain length of alkanols on VE are discussed.

  10. Heat transfer characteristics of UF6 in a container heated from outer surface. Pt. 1. Thermal hydraulic analysis method taking account of phase change and volume expansion

    International Nuclear Information System (INIS)

    Wataru, Masumi; Gomi, Yoshio; Yamakawa, Hidetsugu; Tsumune, Daisuke

    1995-01-01

    Natural UF6 is transported in a steel container from foreign countries to the enrichment plant in Japan. If the container meets fire accident, it is heated by fire (800degC) and rupture of the container may occur. For the safety point of view, it is necessary to know whether rupture occurs or not. Because UF6 has a radiological and chemical hazards, it is difficult to perform a demonstration test with UF6. So thermal calculation method has to be developed. The rupture is caused by UF6 gaseous pressure or volume expansion of liquid UF6. To know time history of internal pressure and temperature distribution in the container, it is important to evaluate thermal phenomena of UF6. When UF6 is heated, it changes from solid to liquid or gas at low temperature (64degC) and then its volume expands little by little. In this study, thermal calculation method has been developed taking phase change and thermal expansion of UF6 into account. In the calculation, a two-dimensional model is adopted and natural convection of liquid UF6 is analyzed. As a result of this study, numerical solutions have been obtained taking phase change and volume expansion into account. (author)

  11. Giant Thermal Expansion in 2D and 3D Cellular Materials.

    Science.gov (United States)

    Zhu, Hanxing; Fan, Tongxiang; Peng, Qing; Zhang, Di

    2018-03-25

    When temperature increases, the volume of an object changes. This property was quantified as the coefficient of thermal expansion only a few hundred years ago. Part of the reason is that the change of volume due to the variation of temperature is in general extremely small and imperceptible. Here, abnormal giant linear thermal expansions in different types of two-ingredient microstructured hierarchical and self-similar cellular materials are reported. The cellular materials can be 2D or 3D, and isotropic or anisotropic, with a positive or negative thermal expansion due to the convex or/and concave shape in their representative volume elements respectively. The magnitude of the thermal expansion coefficient can be several times larger than the highest value reported in the literature. This study suggests an innovative approach to develop temperature-sensitive functional materials and devices. © 2018 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  12. El’ Lisickij grafico costruttivista. La rivista “Vešč’-Gegenstand-Objet”

    Directory of Open Access Journals (Sweden)

    Alice Bravin

    2016-02-01

    Full Text Available This paper analyzes the graphic design of the international art journal “Vešč’-Gegenstand-Objet”, published in Berlin in 1922 by the Russian architect, painter, photographer and designer Lazar’ Markovič Lisickij (1890-1941, better known as El’ Lisickij, together with the Russian writer Il’ja Grigor’evič Èrenburg (1891-1967.Although it lasted only three issues (issues one and two were combined in a single volume which appeared in March/April 1922, while the last number appeared in May 1922, “Vešč’” had a strong influence on contemporary art. It was published in German, French and Russian and was meant both as a bridge between Russia and Europe after the years of war and revolution and as a symbol of the beginning of a new creative era. Mainly focusing on new Suprematist and Constructivist works, the journal included essays on several fields of art such as literature, cinema, theatre, painting, sculpture, architecture and music.In this paper I focus on the innovative graphic design of the two volumes of “Vešč’” entirely realized by El’ Lisickij. Referring to his own theories about book design, Lisickij created a functional and innovative layout and a striking cover, challenging the traditional graphic design practice by using exclusively standard typographic elements such as punctuation marks, typographic lines, geometric forms and typesetting.

  13. Gıdalar ve Mikrobiyolojik Riskler I

    Directory of Open Access Journals (Sweden)

    Velittin Gürgün

    2015-02-01

    Full Text Available Enfeksiyona neden olan ve toksijenik mikroorganizmalarla bulaşan gıdaların tüketilmesi sonucu görülen hastalıklar, acı çekmenin ve ölümlerin en önemli nedenlerinden biridir (Alen ve Kaferstein, 1983. Afrika ve Latin Amerika ile Çin dışındaki Asya ülkelerindeki 5 yaşın altındaki çocuklarda, yılda bir milyarın üzerinde gastroenterik vakaların görüldüğü ve kontamine gıdaların tüketilmesi nedeni ile de bu çocuklardan en az beş milyonunun öldüğü tahmin edilmektedir (Kaferstien ve Sims, 1987. Meksika ve Tayland gibi ülkelerde 0-4 yaş grubun çocukların, en az yarısının Campylobacter’in neden olduğu bağırsak enfeksiyonuna yakalandıkları sanılmaktadır. Avrupa’da ise gıdalardan kaynaklanan hastalıklar, solunum hastalıklarından sonra ikinci sırada yer almakta olup, bir çok Avrupa ülkesinde akut gastro-enteritis hastalığının yılda bir milyon kişiden ellibininde görüldüğü, hatta Hollanda’da bu oranın üçyüzbin olduğu tespit edilmiş bulunmaktadır (Guiguet vd. 1992; Notermans ve Van Der Giessen, 1993. Amerika Birleşik Devletleri için yürütülen tahminlerin bu sayıların da üstünde olduğu ve her yıl ABD’de bir milyon kişiden üçyüzellibin kişinin akut gastroenterik hastalıklara uğradıkları ve bunun da ağırlıklı olarak kontamine gıdalardan kaynaklandığı varsayılmaktadır (Archer ve Kvenberg, 1985. Her ne kadar gelişmiş ülkelerde görülen gıda kaynaklı hastalıklar gelişmekte olan ülkelerdekine göre oldukça düşükse de, sıkça kronikleşerek romatizmal hastalıklar (ankylosing spondylitis ve Reiter’s sendromu beslenme ve emilim bozukluğu problemleri, hemolotik-üremik sendromlar (Escherichia coli’nin özellikle 0157: H7 serotipinin ürettiği verotoksinden dolayı, damar sertliği (atherosclerosis ve Campylobacter türlerinin enfeksiyonunu takiben görülen Guillain-Barre sendromu sonucunu doğurmaktadır (Archer, 1984, 1987; Archer ve

  14. Dissociation of VE-PTP from VE-cadherin is required for leukocyte extravasation and for VEGF-induced vascular permeability in vivo

    Science.gov (United States)

    Broermann, Andre; Winderlich, Mark; Block, Helena; Frye, Maike; Rossaint, Jan; Zarbock, Alexander; Cagna, Giuseppe; Linnepe, Ruth; Schulte, Dörte; Nottebaum, Astrid Fee

    2011-01-01

    We have recently shown that vascular endothelial protein tyrosine phosphatase (VE-PTP), an endothelial membrane protein, associates with VE-cadherin and is required for optimal VE-cadherin function and endothelial cell contact integrity. The dissociation of VE-PTP from VE-cadherin is triggered by vascular endothelial growth factor (VEGF) and by the binding of leukocytes to endothelial cells in vitro, suggesting that this dissociation is a prerequisite for the destabilization of endothelial cell contacts. Here, we show that VE-cadherin/VE-PTP dissociation also occurs in vivo in response to LPS stimulation of the lung or systemic VEGF stimulation. To show that this dissociation is indeed necessary in vivo for leukocyte extravasation and VEGF-induced vascular permeability, we generated knock-in mice expressing the fusion proteins VE-cadherin-FK 506 binding protein and VE-PTP-FRB* under the control of the endogenous VE-cadherin promoter, thus replacing endogenous VE-cadherin. The additional domains in both fusion proteins allow the heterodimeric complex to be stabilized by a chemical compound (rapalog). We found that intravenous application of the rapalog strongly inhibited VEGF-induced (skin) and LPS-induced (lung) vascular permeability and inhibited neutrophil extravasation in the IL-1β inflamed cremaster and the LPS-inflamed lung. We conclude that the dissociation of VE-PTP from VE-cadherin is indeed required in vivo for the opening of endothelial cell contacts during induction of vascular permeability and leukocyte extravasation. PMID:22025303

  15. Kuramsal ve İşlevsel Dil Öğretiminde Tiyatronun Rolü ve Önemi

    Directory of Open Access Journals (Sweden)

    Gıyasettin AYTAŞ

    2017-10-01

    Full Text Available Tiyatro bir sanat faaliyeti olmanın yanında etkili bir iletişim aracıdır. En eski dönemlerden bu yana, hatta insanlığın varlığından itibaren tiyatrodan ve onun etkililiğinden söz etmek olasıdır. Dil edinim süreçleri ile ilgili görüşler birbirinden farklı olmakla birlikte, dilin kullanımında en temel gösterge iletişim ihtiyacıdır. Bununla birlikte dil aynı zamanda bir temsil göstergesidir. Onun aracılığı ile aidiyet ve mensubiyetler hakkında hüküm verilir. Bireyin sosyal ve siyasal özelliklerinin yanında, karakteristik özelliklerini de kullandığı dil aracılığı ile tespit edebilmekteyiz. Tiyatro bu farklılıkların her birini bir arada sergileyen ve somut bir göstergeye dönüştüren bir araç olarak karşımıza çıkmaktadır. Tiyatro yaşanmışlıkları bir araya getirerek iletişim çeşitliliğini ve zenginliğini ortaya koyar. Hayatın hem var olanını hem de olması gerekenlerini birlikte sunar. Her ne kadar bir durum veya olay sonsuz olarak değerlendirilmesi mümkün değilse de tiyatro bu mümkün olmayana varsayımlar açısından yaklaşır. İnsan davranışlarının bilinçli ve bilinçsiz olmak üzere iki göstergesi bulunmaktadır. Bu iki durumla ilgili iletişim yeterliliklerini ve farklılıklarını tiyatro aracılığı ile birlikte görebiliriz. Güzel sanatların hemen tamamını bir arada ve birlikte içinde barındıran tiyatro, bütün dil aşamaların birlikte ve bir arada sunar. Hem iç hem de dış konuşmanın bütün inceliklerini birlikte sunan ve bu özelliği ile karşılıklı ifade çeşitliliğini tiyatro birlikte sunar. İletişim ve dil ediniminde tiyatronun önemini ve gerekliliğini anlamak ve sorgulamak için tiyatronun işlevsel özelliğinden bütün ayrıntıları ile yararlanmak kaçınılmazdır.

  16. A Proposed Stochastic Finite Difference Approach Based on Homogenous Chaos Expansion

    Directory of Open Access Journals (Sweden)

    O. H. Galal

    2013-01-01

    Full Text Available This paper proposes a stochastic finite difference approach, based on homogenous chaos expansion (SFDHC. The said approach can handle time dependent nonlinear as well as linear systems with deterministic or stochastic initial and boundary conditions. In this approach, included stochastic parameters are modeled as second-order stochastic processes and are expanded using Karhunen-Loève expansion, while the response function is approximated using homogenous chaos expansion. Galerkin projection is used in converting the original stochastic partial differential equation (PDE into a set of coupled deterministic partial differential equations and then solved using finite difference method. Two well-known equations were used for efficiency validation of the method proposed. First one being the linear diffusion equation with stochastic parameter and the second is the nonlinear Burger's equation with stochastic parameter and stochastic initial and boundary conditions. In both of these examples, the probability distribution function of the response manifested close conformity to the results obtained from Monte Carlo simulation with optimized computational cost.

  17. 40 CFR 35.926 - Value engineering (VE).

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 1 2010-07-01 2010-07-01 false Value engineering (VE). 35.926 Section... engineering (VE). (a) Value engineering proposal. All step 2 grant applications for projects having a... completion of VE analysis and submittal of VE summary reports). (b) Value engineering analysis. For projects...

  18. Principles of Thermal Expansion in Feldspars

    Science.gov (United States)

    Hovis, Guy; Medford, Aaron; Conlon, Maricate; Tether, Allison; Romanoski, Anthony

    2010-05-01

    Following the recent thermal expansion work of Hovis et al. (1) on AlSi3 feldspars, we have investigated the thermal expansion of plagioclase, Ba-K, and Ca-K feldspar crystalline solutions. X-ray powder diffraction data were collected between room temperature and 925 °C on six natural plagioclase specimens ranging in composition from anorthite to oligoclase, the K-exchanged equivalents of these plagioclase specimens, and five synthetic Ba-K feldspars with compositions ranging from 25 to 99 mol % BaAl2Si2O8. The resulting thermal expansion coefficients (α) for volume have been combined with earlier results for end-member Na- and K-feldspars (2,3). Unlike AlSi3 feldspars, Al2Si2 feldspars, including anorthite and celsian from the present study plus Sr- and Pb-feldspar from other workers (4,5), show essentially constant and very limited thermal expansion, regardless of divalent cation size. In the context of structures where the Lowenstein rule (6) requires Al and Si to alternate among tetrahedra, the proximity of bridging Al-O-Si oxygen ions to divalent neighbors (ranging from 0 to 2) produces short Ca-O (or Ba-O) bonds (7,8) that apparently are the result of local charge-balance requirements (9). Gibbs et al. (10) suggest that short bonds such as these have a partially covalent character. This in turn stiffens the structure. Thus, for feldspar series with coupled substitution the change away from a purely divalent M-site occupant gives the substituting (less strongly bonded) monovalent cations increasingly greater influence on thermal expansion. Overall, then, thermal expansion in the feldspar system is well represented on a plot of α against room-temperature volume, where one sees a quadrilateral bounded by data for (A) AlSi3 feldspars whose expansion behavior is controlled largely by the size of the monovalent alkali-site occupant, (B) Al2Si2 feldspars whose expansion is uniformly limited by partially-covalent bonds between divalent M-site occupants and

  19. 47 CFR 97.513 - VE session manager requirements.

    Science.gov (United States)

    2010-10-01

    ... 47 Telecommunication 5 2010-10-01 2010-10-01 false VE session manager requirements. 97.513 Section... SERVICES AMATEUR RADIO SERVICE Qualifying Examination Systems § 97.513 VE session manager requirements. (a) A VE session manager may be selected by the VE team for each examination session. The VE session...

  20. Production process of VE

    International Nuclear Information System (INIS)

    1987-07-01

    This book tells of synopsis of production process of VE(value engineering), object selection method and establishment of target, collection of object information, design of function, write improvement suggestion, evaluation of improvement suggestion, all sorts of worksheets of production process of VE, explanation of IE, explanation of PERT.

  1. İNOVASYON VE İNOVASYON GÖSTERGELERİ: AB ÜLKELERİ VE TÜRKİYE KARŞILAŞTIRMASI

    OpenAIRE

    ŞAHİNLİ, Mehmet Arif; KILINÇ, Efecan

    2013-01-01

    Literatürde inovasyonu ölçen ve ülkelerin inovasyon performanslarını ortaya koyan birçok gösterge bulunmaktadır. Bilgi yoğun sektörlerdeki istihdam, Toplam Faktör Verimliliği (TFV), AR&GE harcamaları, patent başvuru ve tescil sayıları, girişimci, araştırmacı ve teknisyen sayıları, ileri teknoloji ihracatı, royalti ve lisans ücretleri, endüstri katma değeri, inovasyon kapasitesi ile Bilgi ve İletişim Teknolojileri (BİT)’nin ihracatı bu göstergelerden bazılarıdır. İnovasyonun en önemli ...

  2. Uygulamalı Bilimler ve Mühendislik

    Directory of Open Access Journals (Sweden)

    Recep BAKIŞ

    2011-12-01

    Full Text Available Bu makalede, sanayi, tarım ve evsel atık sularla yoğun bir şekilde kirletilen Porsuk çayı ve havzasındaki yüzeysel ve yeraltı suyu kirlilik düzeyi araştırılmıştır. Bu amaçla, Porsuk çayı boyunca ve havza içinden 20 istasyon seçilerek, 2 yıl boyunca mevsimsel yüzeysel ve yeraltı su örnekleri alınmıştır. Yüzeysel sularda toplam 18, yeraltı sularında ise toplam 15 parametre analiz edilmiştir. Elde edilen sonuçlar, mevsimsel değişikliklerin sebebine bakılmaksızın, Su Kirliliği Kontrolü Yönetmeliği Kıta İçi Su Kaynakları sınıfları ve uluslar arası standartlarla karşılaştırılmıştır. Porsuk çayı ve havzasındaki hem yüzey suyunun hem de yeraltı suyunun IV. Kalite su sınıfında olduğu tespit edilmiştir

  3. Davras Dagı (Isparta ve Çevresinin Orman ve Çalı Vejetasyonu

    Directory of Open Access Journals (Sweden)

    Coşkun SAĞLAM

    2009-04-01

    Full Text Available Bu vejetasyon çalısması, 2002-2005 yılları arasında Batı Toroslar'da yer alan Davras Dagı ve çevresinde gerçeklestirildi. Vejetasyon Braun-Blanquet (1964 metoduna göre analiz edilerek orman ve çalı vejetasyonuna ait yedi birlik tespit edildi. Bunlardan bes tanesi yenidir. Orman vejetasyonu: Sınıf : Quercetea pubescentis (Oberd, 1948 Doing Kraft, 1955 Ordo : Querco – Cedretalia libani Barbéro, Loisel ve Quézel, 1974 1. Minuartio globulosi – Juniperetum excelsae ass. nova 2. Sileno squamigeri – Quercetum cerridis ass. nova 3. Astragalo oxytropifolii – Pinetum caramanicae ass. nova Alyans : Lonicero nummulariaefoliae – Cedrion libani Quézel, Barbéro ve Akman 1978 4. Veronico syriaci – Cedretum libani ass. nova 5. Diantho cibrarii – Quercetum vulcanicae Kurt et al. 1996 Sınıf : Quercetea ilicis Br.-Bl., 1947 Ordo : Quercetalia ilicis Br.-Bl., 1947, Rivaz Martinez, 1974 Alyans : Quercion cocciferae Quézel, Barbéro, Akman, 1978 6. Hyperico polyphylli – Pinetum brutiae ass. nova Çalı Vejetasyonu: Sınıf : Quercetea pubescentis (Oberd, 1948 Doing Kraft, 1955 Ordo : Querco – Cedretalia libani Barbéro, Loisel ve Quézel, 1974 7. Astragalo atropurpureus– Quercetum cocciferae Kargıoglu, 19

  4. A model for phase evolution and volume expansion in tube type Nb3Sn conductors

    Science.gov (United States)

    Xu, X.; Sumption, M. D.; Collings, E. W.

    2013-12-01

    In this work, an analytic model for phase formation and volume expansion during heat treatment in tube type Nb3Sn strands is presented. Tube type Nb3Sn conductors consist of Nb or Nb-Ta alloy tube with a simple Cu/Sn binary metal insert to form the basic subelement (filament). A number of these elements, each with an outer Cu jacket, are restacked to form a multifilamentary strand. The present tube type conductors, with 4.2 K, 12 T non-Cu critical current density (Jc) in the 2000-2500 A mm-2 range and effective subelement diameters (deff) in the 12-36 μm range, are of interest for a number of applications. During the reaction of typical tube type strands, the Sn-Cu becomes molten and reacts with the Nb tube first to form NbSn2, then Nb6Sn5. At later times in the reaction sequence, all of the NbSn2 and Nb6Sn5 is converted to Nb3Sn. Some of the Nb3Sn is formed by a Nb-Sn reaction and has a fine grain (FG) structure, while some is converted from Nb6Sn5, which results in a coarse grain (CG) region. The fractions of FG and CG A15 are important in determining the final conductor properties. In this work we develop an analytic model to predict the radial extents of the various phases, and in particular the final FG and CG fractions based on the starting Nb, Cu, and Sn amounts in the subelements. The model is then compared to experimental results and seen to give reasonable agreement. By virtue of this model we outline an approach to minimize the CG regions in tube type and PIT strands and maximize the final FG area fractions. Furthermore, the volume change during the various reaction stages was also studied. It is proposed that the Sn content in the Cu-Sn alloy has a crucial influence on the radial expansion.

  5. Placental Underperfusion in a Rat Model of Intrauterine Growth Restriction Induced by a Reduced Plasma Volume Expansion.

    Directory of Open Access Journals (Sweden)

    Karine Bibeau

    Full Text Available Lower maternal plasma volume expansion was found in idiopathic intrauterine growth restriction (IUGR but the link remains to be elucidated. An animal model of IUGR was developed by giving a low-sodium diet to rats over the last week of gestation. This treatment prevents full expansion of maternal circulating volume and the increase in uterine artery diameter, leading to reduced placental weight compared to normal gestation. We aimed to verify whether this is associated with reduced remodeling of uteroplacental circulation and placental hypoxia. Dams were divided into two groups: IUGR group and normal-fed controls. Blood velocity waveforms in the main uterine artery were obtained by Doppler sonography on days 14, 18 and 21 of pregnancy. On day 22 (term = 23 days, rats were sacrificed and placentas and uterine radial arteries were collected. Diameter and myogenic response of uterine arteries supplying placentas were determined while expression of hypoxia-modulated genes (HIF-1α, VEGFA and VEGFR2, apoptotic enzyme (Caspase -3 and -9 and glycogen cells clusters were measured in control and IUGR term-placentas. In the IUGR group, impaired blood velocity in the main uterine artery along with increased resistance index was observed without alteration in umbilical artery blood velocity. Radial uterine artery diameter was reduced while myogenic response was increased. IUGR placentas displayed increased expression of hypoxia markers without change in the caspases and increased glycogen cells in the junctional zone. The present data suggest that reduced placental and fetal growth in our IUGR model may be mediated, in part, through reduced maternal uteroplacental blood flow and increased placental hypoxia.

  6. Frontal-insula gray matter deficits in first-episode medication-naïve patients with major depressive disorder.

    Science.gov (United States)

    Lai, Chien-Han; Wu, Yu-Te

    2014-05-01

    This study is designed to investigate the gray matter volume (GMV) deficits in patients with first-episode medication-naïve major depressive disorder (MDD). We enrolled 38 patients with first-episode medication-naïve MDD and 27 controls in this project. Voxel-based morphometry was used to compare GMV differences between two groups. Besides, the relationship between GMV of patients and the severity of clinical symptoms was estimated to confirm the role of GMV deficits in clinical symptoms. The correlation between total GMV and illness duration was also performed to elucidate the impacts of untreated duration on the GMV. We found that first-episode medication-naïve MDD patients had significant GMV deficits in bilateral superior frontal gyri, left middle frontal gyrus, left medial frontal gyrus and left insula. The GMV of patient group was negatively correlated with the severity of clinical symptoms and the illness duration. A pattern of GMV deficits in fronto-insula might represent the biomarker for first-episode medication-naïve MDD. Copyright © 2014 Elsevier B.V. All rights reserved.

  7. Treatment of Severe Edema in Children with Nephrotic Syndrome with Diuretics Alone — A Prospective Study

    Science.gov (United States)

    Kapur, Gaurav; Valentini, Rudolph P.; Imam, Abubakr A.; Mattoo, Tej K.

    2009-01-01

    Background and objective: Severe edema in children with nephrotic syndrome (NS) may be associated with volume contraction (VC) or volume expansion (VE). Usually, severe edema in children is treated with intravenous (IV) albumin and diuretics, which is appropriate for VC patients. However, in VE patients, this can precipitate fluid overload. The objective of this study was to evaluate treatment of severe edema in NS with diuretics alone. Design, setting, participants, & measurements: Thirty NS patients with severe edema were enrolled in this prospective study in two phases. VC was diagnosed based on fractional excretion of sodium (FeNa) diuretics alone and 9 VC patients received albumin and furosemide. There was no difference in hospital stay and weight loss in VC and VE groups after treatment. Conclusions: FeNa is useful in distinguishing VC versus VE in NS children with severe edema. The use of diuretics alone in VE patients is safe and effective. PMID:19406963

  8. Extracellular fluid volume expansion and third space sequestration at the site of small bowel anastomoses.

    Science.gov (United States)

    Chan, S T; Kapadia, C R; Johnson, A W; Radcliffe, A G; Dudley, H A

    1983-01-01

    Intestinal surgery is usually associated with the parenteral administration of sodium and water, sometimes in amounts considerably in excess of excretory capacity. We have studied the effect of this situation on the water content of the gut at and 5 cm from a single-layer end-to-end anastomosis in the rabbit. Water content was measured by desiccation. One group of animals (group 1) did not receive intravenous therapy. The second group (group 2) received 5 ml kg-1 h-1 of Hartmann's solution during the operative period and thereafter to a total volume of 200 ml by 48 h. In group 1 there was a 5-10 per cent increase in tissue weight both at the anastomotic site and at 5 cm (P less than 0.01, Mann-Whitney U test) on the first 3 days. Thereafter, water content at the anastomosis persisted, but resolved in normal gut. In group 2 a further 5 per cent increase in weight over group 1 occurred (P less than 0.01), persistent at the anastomotic site over 5 days, though resolving elsewhere after 2 days. Extracellular fluid volume expansion exaggerates an anatomical third space present in the region of an anastomosis. At the suture line, oedema so induced is persistent and could be deleterious.

  9. Effect of volume loading on the Frank-Starling relation during reductions in central blood volume in heat-stressed humans

    DEFF Research Database (Denmark)

    Bundgaard-Nielsen, Morten; Wilson, T E; Seifert, Thomas

    2010-01-01

    -body heating after intravascular volume expansion. Volume expansion was accomplished by administration of a combination of a synthetic colloid (HES 130/0.4, Voluven) and saline. Before LBNP, SV was not affected by heating (122 +/- 30 ml; mean +/- s.d.) compared to normothermia (110 +/- 20 ml; P = 0...

  10. Probiyotik Mayalar ve Özellikleri

    Directory of Open Access Journals (Sweden)

    Hatice Yıldıran

    2017-10-01

    Full Text Available Probiyotikler tüketicinin sağlığı üzerinde olumlu etkileri olan mikroorganizmalardır. Probiyotik uygulamalarının sağlık üzerine etkileri hakkında yapılmış pekçok araştırma bulunmaktadır. En yaygın kullanılan probiyotik bakteriler; bifidobakteriler ve laktobasiller, laktokoklar ve streptokoklar gibi laktik asit bakterileridir. İnsanlar için probiyotik olarak kullanılan mikroorganizmalar arasında ayrıca mayalar, basiller ve enterokoklar da bulunmaktadır. Probiyotik mayalar son yıllarda bilim insanları için ilgi çekici bir alan olmuştur. Yapılan bazı çalışmalar Saccharomyces cinsine ait türlerin antibakteriyel ve probiyotik özelliklere sahip olabileceklerini göstermiştir. Saccharomyces boulardii yıllardır insanları farklı gastrointestinal rahatsızlıklarından korumak veya hastalıklardan iyileştirmek amacıyla probiyotik olarak kullanılan, patojenik olmayan bir mayadır. S. boulardii özellikle ilaç endüstrisinde genellikle liyofilize formda kullanılmaktadır. Yapılan bu derleme çalışmasında probiyotikler, mayaların probiyotik olma özellikleri ve probiyotik mayaların kullanım alanları hakkında bilgiler verilmiş ve bu alanda yapılan araştırmalardan örnekler sunulmuştur.

  11. Kedi ve Köpeklerde Diabetes Mellitus.

    OpenAIRE

    ŞİMŞEK, Aynur; İÇEN, Hasan

    2008-01-01

    Diabetes mellitus polidipsi, poliüri ve polifaji gibi klinik bulgularla karakterize endokrin bir hastalıktır. Bu derlemede, kedi ve köpeklerde yaygın olan hastalığın etiyoloji, patogenezis, kliniklaboratuar bulguları, tanı, ayırıcı tanı ve sağaltımına yönelik bilgilerin verilmesi amaçlanmıştır

  12. Yerelden Evrensele Japon Anime ve Manga Sanatı

    OpenAIRE

    TAŞ ALİCENAP, Çiğdem

    2014-01-01

    Anime ve manga kültürü Uzakdoğu çizgi roman sanatının yoğun üretimi, tarih, din, kültür ve felsefenin konulara yansıması ve Batı çizgi film ve çizgi romanlarından ayrılan farklı tarzlarıyla araştırılması ve öğrenilmesi gereken değerler içermektedir. Japonya’ da çizgi film sanatının Batı’ daki Disney gibi bir endüstrinin dışında bu denli özgün ve başarılı örnekleri elbette o sanatçıların yetiştiği kültürün, tarihin, sanatın ve felsefi değerlerin olduğu kadar eski...

  13. Postoperative volume balance

    DEFF Research Database (Denmark)

    Frost, H; Mortensen, C.R.; Secher, Niels H.

    2017-01-01

    In healthy humans, stroke volume (SV) and cardiac output (CO) do not increase with expansion of the central blood volume by head-down tilt or administration of fluid. Here, we exposed 85 patients to Trendelenburg's position about one hour after surgery while cardiovascular variables were determin...

  14. Rizâeddin b. Fahreddin ve Kütüb-i Sitte ve Müellifleri adlı eseri

    OpenAIRE

    KHAZİEV, Rinat

    2015-01-01

    Tez bir Girişten ve üç bölümden oluşmaktadır. Girişte tezin içerdiği bilgiler ve hazırlanmasında izlenen yöntem hakkında bilgiler verilmiştir.Tezin birinci bölümünde Rizâeddin b. Fahreddin’in hayatına dair bilgiler sunulmuştur. Onun şahsiyeti, âlimliği, başmuharrirliği ve sosyal faaliyetleri gösterilmiştir. Diğer taraftan da onun hayatı, ilmi tahsili, hocaları ve eserleri ele alınmıştır.Araştırmanın ikinci bölümde Rizâeddin b. Fahreddin’n Hadis ilmine bakışı ve yaklaşımı tahlil edilm...

  15. Origami structures for tunable thermal expansion

    Science.gov (United States)

    Boatti, Elisa; Bertoldi, Katia

    Materials with engineered thermal expansion, capable of achieving targeted and extreme area/volume changes in response to variations in temperature, are important for a number of aerospace, optical, energy, and microelectronic applications. While most of the proposed structures with tunable coefficient of thermal expansion consist of bi-material 2D or 3D lattices, here we propose a periodic metastructure based on a bilayer Miura-Ori origami fold. We combine experiments and simulations to demonstrate that by tuning the geometrical and mechanical parameters an extremely broad range of thermal expansion coefficients can be obtained, spanning both negative and positive values. Additionally, the thermal properties along different directions can be adjusted independently. Differently from all previously reported systems, the proposed structure is non-porous.

  16. Tanenler ve Hayvan Besleme Üzerine Etkileri

    Directory of Open Access Journals (Sweden)

    Esin Ünver

    2014-06-01

    Full Text Available Tanenler; bitkilerin yapısında doğal olarak bulunan, kendilerini patojen mikroorganizmalara ve virüslere karşı korumak için ürettikleri fenolik bileşiklerdir. Hayvan besleme açısından ise tanenler; hayvanın türü, fizyolojik durumu, tanenin yapısı ve miktarına bağlı olarak olumlu ve olumsuz etkilere sebep olabilmektedirler. Bu çalışmanın amacı; tanenler, etkileri ve hayvan beslemede kullanımları ile ilgili bir derleme sunmaktır.

  17. Form factor expansion for thermal correlators

    NARCIS (Netherlands)

    Pozsgay, B.; Takács, G.

    2010-01-01

    We consider finite temperature correlation functions in massive integrable quantum field theory. Using a regularization by putting the system in finite volume, we develop a novel approach (based on multi-dimensional residues) to the form factor expansion for thermal correlators. The first few terms

  18. Melatonin ve Klinik Önemi

    OpenAIRE

    Fehmi, Özgüner; Özcankaya, Ramazan; Delibaş, Namık; Koyu, Ahmet; Çalışkan, Sadettin

    2009-01-01

    SüleymanDemirel Üniversitesi TIP FAKÜLTESİ DERGİSİ: 1995 Aralık; 2(4) Melatonin ve Klinik Önemi Fehmi Özgüner Ramazan Özcankaya Namık Delibaş Ahmet Koyu Sadettin Çalışkan . Özet Melatonin karanlık periyotta sentezlenir ve salınır, ayrıca karanlığın süresi hakkındaki bilginin değerlendirilmesine aracılık eder. Melatonin sirkadiyan ritmi, gençlerde oldukça düzenlidir, yaşlılıkta sıklıkla siklus bozulma gösterir ve bir hipomelatoninemi sendromu ola...

  19. Tom Stoppard'ın Rosencrantz ve Guildenstern Öldüler Adlı Oyununda Mizah ve Kader

    OpenAIRE

    Erkan, Ayça Ülker

    2016-01-01

    Bu çalışmanın amacı karakterlerin kimlik arayışından kaynaklanan fiziksel mizahı tartışmak ve oyundaki ölüm/şans/kader/gerçeklik/yanılsama gibi temaların Rosencrantz ve Guildenstern’nin varoluşçu hayatlarında nasıl işlediğini göstermektir. Mizah, bu trajikomedinin analiz edilmesinde önemli bir rol oynar. Absürd Tiyatro, insanlık durumundaki saçmalığı ifade eder, rasyonel aygıtların kullanımını terk eder, insanın trajik kaybolmuşluk duygusunu yansıtır ve insanlık durumu olan hayat ve ölümle il...

  20. Uygulamalı Bilimler ve Mühendislik

    Directory of Open Access Journals (Sweden)

    Recep BAKIŞ

    2012-06-01

    Full Text Available Türkiye’de enerji ihtiyacı, ülkenin öz kaynaklarından karşılanamadığı için yurt dışından ithal edilmektedir. Oysa Türkiye’nin zengin yenilenebilir su kaynakları vardır. Bu makalede, Nehil Çayının (Zap suyu alt havzası sahip olduğu hidroelektrik enerji potansiyeli, bu kaynağın efektif kullanımına ve böylece ülkenin enerji açığını kısmen kapatmaya yönelik olarak araştırılmıştır. Araştırma, Coğrafi Bilgi Sistemleri (GIS ve Uzaktan Algılama metotları kullanılarak yapılmıştır. Ön araştırmaya göre, Nehil Çayı havzasında bir adet barajın planlaması yapılmış ve bu barajın olası maliyetleri ve buradan temin edilebilecek yıllık elektrik enerjisi miktarı hesaplanmıştır. Barajın toplam maliyetleri ve kurulu gücü Simahpp yazılımı ile hesaplanmıştır. Simahpp yazılımına göre, Nehil Çayı havzasında planlanan barajın toplam maliyeti ve kurulu gücü, 41,3x106 US$ ve 25,2 MW olarak elde edilmiştir. Yılda üretebileceği elektrik enerjisi miktarı ise 39,8 GWh olarak belirlenmiştir

  1. Yaşam Bilimleri ve Biyoteknoloji

    Directory of Open Access Journals (Sweden)

    Kazım UYSAL

    2011-02-01

    Full Text Available Yoğun zirai faaliyetlerin yapıldığı Antalya’nın batı sahillerinden yakalanan ekonomik önemi olan bazı deniz balıklarının (Diplodus sargus, Siganus rivulatus, Lithognathus mormyrus, Liza aurata, Chelon labrasus kas, deri ve solungaçlarındaki bakır, çinko, mangan, demir ve magnezyum (Genellikle zirai aktivitelerden kaynaklanırlar biyoakümülasyon seviyeleri araştırılmıştır. Balıkların dokularında incelenen elementlerin minimum ve maksimum seviyeleri (mg kg-1 yaş ağırlık bakır için 0.541.69; çinko için 4.14-407.23; mangan için 0.15-9.17; demir için 3.45-104.49 ve magnezyum için 204.33- 784.30 olarak tespit edilmiştir. İncelenen elementlerin en düşük biyoakümülasyon seviyeleri kas dokularda, en yüksek seviyeler (Bakır hariç ise solungaçlarda tespit edilmiştir. İncelenen türlerin kas dokularındaki bakır ve çinko seviyeleri (Dünya Sağlık Örgütü (WHO, Gıda ve Tarım Örgütü (FAO ve Türk Gıda Kodeksi’nde belirtilen kabul edilebilir maksimum seviyelerden daha düşük, bazı türlerin (D. sargus, S. rivulatus, L. mormyrus and L. aurata derilerinde bulunan çinko seviyeleri ise kabul edilebilir maksimum seviyelerden daha yüksek bulunmuştur

  2. Effect of gas expansion on the front shape of a Taylor bubble: an experimental contribution

    Directory of Open Access Journals (Sweden)

    Santos Laura

    2014-03-01

    Full Text Available An experimental study where an individual Taylor bubble rises through water with different bubble volume expansion rates is presented with the (front bubble shape determination as main objective. A combination of two techniques, Particle Image Velocimetry (PIV and Pulsed Shadowgraphy (PS, was used to collect images for further treatment in order to characterize the liquid flow pattern in front of the bubble and the bubble shape. Processing the images acquired with pulsed illumination from behind the bubble it was possible to define with precision the bubble shape at different stages when it was expanding. The operation conditions used allowed a wide range of volume expansion rates (0 to 28.5 × 10-6 m3/s with a significant effect on the Taylor bubble velocity; increases in bubble velocity up to 21% were observed relatively to constant volume system condition. Nevertheless, it seems that the front shape of Taylor bubbles does not change significantly with the upward liquid flow rates induced by gas expansion, at least for the volume expansion rates used in the experiments.

  3. Low Thermal Expansion Glass Ceramics

    CERN Document Server

    Bach, Hans

    2005-01-01

    This book appears in the authoritative series reporting the international research and development activities conducted by the Schott group of companies. This series provides an overview of Schott's activities for scientists, engineers, and managers from all branches of industry worldwide in which glasses and glass ceramics are of interest. Each volume begins with a chapter providing a general idea of the current problems, results, and trends relating to the subjects treated. This new extended edition describes the fundamental principles, the manufacturing process, and applications of low thermal expansion glass ceramics. The composition, structure, and stability of polycrystalline materials having a low thermal expansion are described, and it is shown how low thermal expansion glass ceramics can be manufactured from appropriately chosen glass compositions. Examples illustrate the formation of this type of glass ceramic by utilizing normal production processes together with controlled crystallization. Thus g...

  4. Cordia Sebestena Tohumunun ve Tohum Yağının Besinsel Özellikleri ve Potansiyel Değeri (İngilizce

    Directory of Open Access Journals (Sweden)

    Foluso O. Agunbiade

    2015-02-01

    Full Text Available Az kullanılan hammaddelerin geliştirilmesinin ivme kazanması ile iyi bilinen tohum ve tohum yağlarına olan aşırı bağımlılıktan ve bunun sonucundaki yüksek maliyetten dolayı geleneksel ve endüstriyel uygulamalar için az bilinen tohum ve tohum yağları türetilmiştir. Bu nedenle Cordia sebestena tohum ve tohum yağının kullanım potansiyeli bakımından besinsel özelliklerinin değerlendirilmesine yönelik bu çalışma yapılmıştır. Tohum yağında literatürde rapor edilen çeşitli analizler kullanılarak yağ asidi profili incelenmiş ve karakterize edilmişken, tohumda ise genel bileşim, mineral bileşenler ve anti-besinsel faktörler araştırılmıştır. Sonuçlar tohumun iyi bir yağ (%40.3 ± 0.8 ve protein (%11.5 ± 0.6 kaynağı olabileceğini göstermektedir. Tohum aynı zamanda Mg, Ca ve Na benzeri bazı makro-elementler ile esansiyel bir mikro-element olan Zn kaynağı olabilir. Anti-besinlerden fitat, tanen ve oksalat içeriği yüksektir ve gıdalarda tohumun kullanımı sakıncalı olabilir. Bu maddeler belki geleneksel gıda işleme yöntemleri ile giderilebilir. Tohum yağının özellikleri onun alkid reçine sentezinde, biyodizel ve sabun üretiminde kullanışlı olabileceğini göstermektedir. Yağ asidi profili toplam yağın %71.1 oranında insan tüketimi için iyi bir yağ asidi olan oleik asiti (C18:1 ağırlıklı olarak bulundurduğunu göstermektedir. Cordia sebestena tohumu ve tohum yağının önemli kullanım alanları olabileceği görülmüştür, ancak tohum yağının aminoasit profili ve anti-besinler üzerine geleneksel işlemlerin etkileri konularında daha fazla çalışmaya ihtiyaç vardır.

  5. Cabernet Sauvignon ve Merlot Şarapların Resveratrol Düzeyleri ve Ekolojik Koşulların Etkileri

    Directory of Open Access Journals (Sweden)

    Belkıs Çaylak Adıgüzel

    2015-02-01

    Full Text Available Fitoaleksinler bitkilerde patojen enfeksiyonuna bir reaksiyon olarak veya çeşitli biyotik ve abiyotik tetikleyicilerin etkisi sonucu oluşan fenolik madde karakterli, düşük molekül ağırlıklı antimikrobiyal bileşiklerdir. Resveratrol (trans–3,5,4’-trihidroksistilben de bir fitoaleksin olup, asma (Vitis vinifera, yer fıstığı (Arachis hypogaea ve diğer pek çok bitki türünde yaprak veya diğer organlarda yüksek miktarlarda bulunabilmektedir. Resveratrol asmada gövde, sürgün ve yapraklar yanında, özellikle renkli çeşitlerin tane kabuğunda bol miktarda sentezlenebilmekte ve şarap yapımı sırasında şıraya, şıradan da şaraba geçmektedir. Son yıllarda resveratrolün antikanserojen özelliği ve antioksidan karakteri nedeniyle sağlık yararları üzerine yoğun araştırmalar yapılmakta ve günlük diyette alımı önerilmektedir. Bu çalışmada, Ege, Marmara ve Trakya Bölgeleri’nde üretilen kimi bağlardan sağlanan Cabernet sauvignon ve Merlot siyah üzümlerinden üretilmiş şaraplarda bulunan resveratrol miktarları Yüksek Performanslı Sıvı Kromatografisi yöntemi kullanılarak belirlenmiştir. Elde edilen sonuçlar bölgelerin ekolojik koşulları açısından birbirleriyle karşılaştırılmış ve resveratrol miktarı ile bu parametreler arasındaki korelasyon araştırılmıştır. Resveratrol konsantrasyonunun üzüm çeşidi ve bölgelerin iklim şartlarına bağlı olarak farklılıklar gösterebileceği görülmüştür.

  6. Laurus nobilis, Vitex agnus-castus ve Tamarix parviflora Türlerinin Kimyasal İçeriği ve Fenolik Ekstraktiflerinin İncelenmesi

    Directory of Open Access Journals (Sweden)

    Samim YAŞAR

    2016-05-01

    Full Text Available Bu çalışmada Laurus nobilis, Vitex agnus-castus ve Tamarix parviflora bitkilerinden alınan örneklerde kimyasal bileşim ve fenolik ekstraktifler incelenmiştir. Bu türlerin endüstriyel anlamda oduna alternatif olabilirliği ve antioksidan üretiminde hammadde olarak kullanılabilirliği değerlendirilmiştir. Laurus nobilis, Vitex agnus-castus ve Tamarix parviflora bitkilerine ait örneklerde holoselüloz, selüloz, α-selüloz, lignin ve kül miktarları ile etanol siklohekzan, soğuk su, sıcak su ve %1 NaOH çözünürlükleri sırasıyla %73.26-76.32, %53.58-54.52, %43.28-44.73, %20.39-21.27, %2.12-2.79, %2.49-2.71, %9.67-11.70, %10.77-12.42 ve %21.77-24.48 aralığında bulunmuştur. HPLC analizleri toplam fenolik madde miktarının Vitex agnus-castus’da (2.09 mg/g, Tamarix parviflora’da (1.05 mg/g ve Laurus nobilis’de (0.58 mg/g olduğunu göstermiştir. Laurus nobilis’te en yüksek miktardaki fenolik ekstraktif madde epikateşin (0.23 mg/g ve Tamarix parviflora’da gallik asit (0.17 mg/g olarak belirlenmiş, Vitex agnus-castus’da ise p-hidroksibenzoik asit (0.95 mg/g olarak tespit edilmiştir. Elde edilen sonuçlar, çalışma konusu bitkilerin iğne yapraklı ve yapraklı türlerle karşılaştırılabilir düzeyde olduğunu göstermiş olup, söz konusu maki türlerinin orman ürünleri endüstrisinde ve ticari antioksidan üretiminde hammadde olarak kullanılabileceklerini ortaya koymuştur.

  7. Expansion and maintenance of human embryonic stem cell–derived endothelial cells by TGFβ inhibition is Id1 dependent

    Science.gov (United States)

    James, Daylon; Nam, Hyung-song; Seandel, Marco; Nolan, Daniel; Janovitz, Tyler; Tomishima, Mark; Studer, Lorenz; Lee, Gabsang; Lyden, David; Benezra, Robert; Zaninovic, Nikica; Rosenwaks, Zev; Rabbany, Sina Y; Rafii, Shahin

    2010-01-01

    Previous efforts to differentiate human embryonic stem cells (hESCs) into endothelial cells have not achieved sustained expansion and stability of vascular cells. To define vasculogenic developmental pathways and enhance differentiation, we used an endothelial cell–specific VE-cadherin promoter driving green fluorescent protein (GFP) (hVPr-GFP) to screen for factors that promote vascular commitment. In phase 1 of our method, inhibition of transforming growth factor (TGF)β at day 7 of differentiation increases hVPr-GFP+ cells by tenfold. In phase 2, TGFβ inhibition maintains the proliferation and vascular identity of purified endothelial cells, resulting in a net 36-fold expansion of endothelial cells in homogenous monolayers, which exhibited a transcriptional profile of Id1highVEGFR2highVE-cadherin+ ephrinB2+. Using an Id1-YFP hESC reporter line, we showed that TGFβ inhibition sustains Id1 expression in hESC-derived endothelial cells and that Id1 is required for increased proliferation and preservation of endothelial cell commitment. Our approach provides a serum-free method for differentiation and long-term maintenance of hESC-derived endothelial cells at a scale relevant to clinical application. PMID:20081865

  8. Domates Pulpu ve Salçasında Viskozite (Konsistens ve Renk Üzerine Proses Koşullarının Etkisi

    Directory of Open Access Journals (Sweden)

    Aziz Ekşi

    2015-02-01

    Full Text Available Kıvam ve renk, domates pulpu ve salçada kaliteyi belirleyen ve ticarette üzerinde en çok durulan iki önemli etkendir. Domates salçasında renk ve kıvam ile hammaddenin durumu arasında yakın bir ilişki bulunduğu bilinmektedir. Ancak her iki kalite öğesini ve özellikle kıvamı, hammadde olduğu kadar, proses koşulları da etkilemektedir.

  9. Ortopedik Engelli ve Engelli Olmayan Erkek Ergenlerde Benlik Saygısı ve Beden İmajı

    Directory of Open Access Journals (Sweden)

    Sema Kaner

    2000-02-01

    Full Text Available Bu araştırma, ortopedik engelli ve engelli olmayan ergenlerin benlik saygılarını ve beden imajı algılarını karşılaştırmalı olarak incelemeyi amaçlamaktadır. Veriler 55 ortopedik engelli erkek ve 123 normal erkek ergenden Kendine Saygı Ölçeği ve Beden İmajı Anketi ile toplanmıştır. Sonuçlar, grupların benlik saygıları açısından farklı olmadığım, ancak ortopedik engelli erkeklerin beden imajı algılarının engelli olmayan erkeklerinkinden daha olumlu olduğunu göstermektedir. Engelli olmayan erkeklerde benlik saygısı ve beden imajı arasında anlamlı ve olumlu yönde bir ilişki olmasına rağmen, ortopedik engelli erkeklerde bu iki değişken arasında bir ilişki bulunamamıştır. Engelli olmayan erkeklerde benlik saygısını en iyi yordayıcı değişkenler cinsel organlar, boy, ayaklar ve spor yeteneği, ortopedik engellilerde ise bacaklar, ten, omuzlar, beden kılı ve saçlardır. This study was designed to determine whether self-esteem and body image perception differed among orthopedically handicapped and normal adolescents. Data were collected from 55 orthopedically handicapped males and 123 normal males using Self-Esteem Scale and Body image Questionnaire. The results show that there were no significant differences on the self-esteem scores between groups but body image scores ofthe handicapped males in two groups were higher than the normal femalesAlthough it was found that a positive and significant correlation exist between self-esteem and body image perceptions of nonhandicapped males, no such correlation was foundfor handicapped males. The most predictive body aspects of self-esteem were genital organs, height, legs and sports ability in nonhandicapped males, and legs, skin, shoulders, amount of hair on theface and scalp in orthopedically handicapped males.

  10. The intrinsic thermal expansion of point defects in Al

    International Nuclear Information System (INIS)

    Asty, Michel.

    1975-11-01

    The differential length measurement between two specimens, on pure and the other containing point defects, leads to the intrinsic thermal coefficient of expansion β(d) of the defect. A differential dilatometer by Laser interferometry is described operating between 77 and 300 K, with a sensitivity of about 100A on the length difference between an alloy sample and a pure dummy. Concerning substitutional impurities in aluminium between -190 deg C and -90 deg C, the intrinsic thermal coefficient of expansion of the defect β(d) is shown to have an absolute value much larger than the thermal expansion coefficient β 0 of the aluminium matrix: β(d)/β 0 =+3 to +6 for the magnesium impurity, β(d)/β 0 =-3 to -4 for the calcium impurity, and to be independent of the temperature. The existing theoretical models give evaluations for away from modeles theoriques existant sont tres loin d'expliquer les resultats experimentaux. high temperature, the results show that vacancies and divacancies, before collapsing in dislocation loops, form multivacancy clusters with large formation volumes: such a property makes these clusters comparable to cavities where the formation volume per vacancy is equal to the atomic volume of the matrix [fr

  11. Vişne ve Nar Suyu ve Konsantratlarında Antosiyaninlerin Degradasyonu

    Directory of Open Access Journals (Sweden)

    Narmela Asafı

    2015-02-01

    Full Text Available Nar ve vişne suyu konsantratlarında antosiyaninlerin parçalanması üzerine sıcaklığın etkisi incelenmiştir. 70°Bx'lik konsantratlardan 45°Bx ve 15° Bx lik örnekler hazırlanarak -18°C, 5°C, 20°C ve 37°C depolanmıştır. Depolanma süresince, sıcaklık dercesine bağlı olarak değişik aralıklarla alman örneklerde antosiyanin kaybı saptanarak parçalanma hızı incelenmiştir. Elde edilen bulgulara göre antosiyaninlerin parçalanma­sı birinci dereceden bir reaksiyon kinetiğine göre gelişmektedir. Tüm örneklerde beklendiği gibi sıcaklık derecesi yükseldikçe antosiyaninlerin degradasyon hızları artmaktadır. Örneğin 15° Bx'lik vişne suyunda -18°C'de hız konsantı k=0.534 x 10-3 gün-1 olduğu halde, 37°C'de k= 184 x 10-3 gün-1 'e yükselmiştir. Aynı şekilde 15° Bx'lik vişne suyunda -18°C'de hız konstantı k= 0.203 x 10-3 gün-1 olduğu halde 37°C'de k= 94 x10-3 gün-1'e yükselmiştir. Ayrıca reaksiyonun sıcaklığa bağımlılığı, Arrhenius eşitliğinden yararlanarak açıklanmaya çalışılmıştır. Nar suyu ve konsantratlannda antosiyaninlerin degradasyon hızı, vişne suyu ve konsantratlarında olduğundan daha yüksektir. Böylece nar suyu ve konsantratlarında depolama süresince sıcaklığa bağlı olarak hızla renk kaybı oluşmaktadır. Ayrıca doğal briksindeki vişne suyunda antosiyaninler, konsantratlarda olduğundan daha stabil olduğu halde nar suyunda bunun aksine konsantratlardaki antosiyaninlerin daha stabil ol­duğu anlaşılmaktadır.

  12. Bitkisel Ürünlerin ve Gıda Destek Ürünlerinin İçeriklerinin Adli ve Hukuki Boyutu

    Directory of Open Access Journals (Sweden)

    Zeynep Türkmen

    2014-09-01

    Full Text Available Günümüzde alternatif ya da destekleyici tedavi yöntemlerine ve bunlara bağlı olarak bitkisel ürünlere artan bir ilgi söz konusudur. Bu ürünler Gıda, Tarım ve Hayvancılık Bakanlığı’ndan gıda destek maddesi ruhsatı alınarak, “gıda takviyesi” adı altında piyasaya sürülmektedir. Bu tip ürünler ilaç statüsünde olmadığından ruhsatlandırılması ve piyasaya arzı farklılık gösterebilmektedir. Bu ürünlerle ilgili sıklıkla gözlenen sorunlar arasında kontaminasyon, katkı maddeleri, toksisite ve yanlış doz ve etiketlemeden kaynaklı tek tip üretim problemleri sayılabilir. Son zamanlarda söz konusu ürünlere ait zehirlenmeler ve ilaç etkileşimlerinin neden olduğu istenmeyen ve beklenmeyen durumlar gözlemlenmektedir. Bu gözlemler, alternatif ya da destekleyici ürün adı altında piyasaya sunulan bitkisel ürünlerin üretimi, ruhsatlandırılması, satışı ve denetimi konusunda ciddi düzenlemelere ve uygulamalara ihtiyaç olduğunu göstermektedir. Çalışmamızın amacı, laboratuarımıza içerik analizi için yönlendirilen, ikisi bakanlık onayı olmaksızın bitkisel ürün adı altında satılmakta olan, diğeri ise bakanlık onaylı sporcu destek ürünü olmak üzere üç olgudan elde edilen bulgularımızı sunmak ve ilgili olguları Türk Ceza Kanunun hükümlerine göre değerlendirmektir. Anahtar kelimeler: Bitkisel ürünler, Sibutramine, sporda kullanılan destek ürünleri, Cinnarizine, GC-MS.

  13. Simidin Demir ve Çinko Mineralleriyle Zenginleştirilmesi ve in vitro Mineral Biyoyararlılığının Saptanması

    Directory of Open Access Journals (Sweden)

    Melis Sözer Güzelcan

    2015-02-01

    Full Text Available Bu çalışmada, Türkiye’de sıklıkla görülen mineral yetersizliğine bağlı beslenme sorunlarına bir yaklaşım olması açısından geleneksel bir gıda olan simidin demir ve çinko mineralleri ile zenginleştirilmesi, bu mi­nerallerin biyoyararlılığı ve genellikle simit ile birlikte tüketilen çay ve ayran içeceklerinin mineral biyoya­rarlılığı üzerine etkileri ve ayrıca tahıllı gıdalarda bulunan fitik asidin mineral biyoyararlılığına etkisinin saptanması amaçlanmıştır. Bu amaçla, simit, demir ve çinko mineralleri ile zenginleştirilmiş simit, çay + zenginleştirilmiş simit ve ayran + zenginleştirilmiş simit örneklerinde demir ve çinko minerallerinin içe­rikleri ve in vitro mineral biyoyararlılıkları saptanmıştır. Simit, demir ve çinko mineralleri ile zenginleşti­rilmiş simit örneklerinde fitik asit içerikleri de belirlenmiştir. Çalışma sonucunda; simitteki demir ve çinko minerallerinin biyoyararlılıkları sırasıyla % 3.14 ve % 6.78; zenginleştirilmiş simitteki bu minerallerin biyo­yararlılıkları sırasıyla % 1.96 ve % 2.84 olarak saptanmıştır. Demir mineralinin biyoyararlılığı simit ayran ve çayla tüketildiği zaman sırasıyla % 2.14 ile % 2.23; çinko mineralinin biyoyararlılığı sırasıyla % 6.38 ve % 5.09 olarak belirlenmiştir. Çay ve ayran zenginleştirilmiş simit ile birlikte tüketildiği zaman demir mineralinin biyoyararlılığının değişmediği; çinko mineralinin biyoyararlılığının arttığı saptanmıştır. Simit ve zenginleş­tirilmiş simitteki fitik asit içerikleri sırasıyla 0.154 g/100g ve 0.159 g/100g olarak belirlenmiştir. Fitat:demir minerali ve fitat:çinko minerali molar oranları hesaplanarak mineral biyoyararlılığı değerlendirilmiştir.

  14. Turist Motivasyonunda Mahalli Kültür ve Etkisi ve Apart Ziyaretlerinde Turist Memnuniyeti

    Directory of Open Access Journals (Sweden)

    Nguyen Quang VINH

    2013-09-01

    Full Text Available Bu çalışma, apart turizm hizmet sektöründe stratejik pazarlama kararının tesis edilmesi anlayışını sağlamak için turizm planlamacılarına ve turizmcilere yardım etmeyi amaçlamaktadır. Ampirik analiz için Duonglam Eski Köyü’nün apart hizmetinden faydalanmış 150 uluslararası ziyaretçinin oluşturduğu datalar kullanılmıştır. Turist motivasyonu ve nihai varış noktası sadakatindeki memnuniyet arasındaki hipotezleri test etmek amacıyla regresyon yöntemi benimsenmiştir. Bu çalışma Duonglam köyündeki iklim şartları, nihai varış noktasına ulaşım kolaylığı, konaklama kalitesi, doğal güzellikler ve hijyen şartlarının turist memnuniyeti üzerinde önemli etkileri olduğu sonucunu çıkarmıştır. Diğer taraftan da bu sonuçlar Duonglam Eski Köyü’nün kültürel aktiviteleri ve turizm hizmet sektörü hakkında olumsuz bir kanıyı temsil etmektedir. Ayrıca çalışmada, araştırmanın sınırı ve turizm sektörü çalışanları için elde edilen bulguların sonuçları tartışılmıştır.

  15. KENTSEL VE KOLEKTİF BELLEKTE KIRILMALAR VE KAMUSAL ALANIN DÖNÜŞÜMÜ: GİRNE ŞEHRİ LİMANI ÖRNEĞİ

    Directory of Open Access Journals (Sweden)

    Ümmü ALTAN BAYRAKTAR

    2015-09-01

    Full Text Available Özet Günümüzde modernleşme ve kapitalizm etkisinde, maddi, toplumsal ve bireysel yaşam büyük bir hız ve ölçekle değişmektedir. Yaşamlarımızın geçtiği mekanların da aynı hız ve ölçekle değişip dönüşmesi, insanların geçmiş ile bugün arasındaki dinamikleri daha fazla sor- gulamasına neden olmuştur. Bu da bellek ve mekan arasındaki ilişkiyi araştırmayı gündeme getirmiş; diğer çalışmaların yanında, kamusal alan olarak kentin ve kentselliğin sürdürülebil- mesini sağlayan kent merkezlerinin çok katmanlı tarihi dokusunun varlığı, geçirdiği değişim ve dönüşümü anlama çabalarını arttırmıştır. Günümüzde ekonomik rasyonalite mantığıy- la atılan adımlar sonucunda tarihsel-kültürel miras ve tarihsel kentsel dokular yitirilmeye başlanmıştır. Bu değişim ve dönüşüm kentsel ve kolektif bellekte kırılmalar yaşanmasına ve kamusal alanların yaşanan mekanlar olmaktan çıkmasına neden olmuştur. Kıbrıs’ın Girne Şehri’nde yer alan ‘Liman’, tarihsel süreç içerisindeki gelişimi, fiziki ve sosyal özellikleriyle kentsel ve kolektif bellekte varolan kırılmalar ve kamusal alanın dönüşümünde mekan ve iktidar açısından bu çalışma kapsamında ele alınmıştır. Çalışmanın kuramsal alt yapısı Jür- gen Habermas’ın Kamusal Alan ve Maurice Halbwachs’ın Kolektif Bellek kavramı üzerine kurulmaya çalışılmıştır.

  16. Changes of pituitary gland volume in Kennedy disease.

    Science.gov (United States)

    Pieper, C C; Teismann, I K; Konrad, C; Heindel, W L; Schiffbauer, H

    2013-12-01

    Kennedy disease is a rare X-linked neurodegenerative disorder caused by a CAG repeat expansion in the first exon of the androgen-receptor gene. Apart from neurologic signs, this mutation can cause a partial androgen insensitivity syndrome with typical alterations of gonadotropic hormones produced by the pituitary gland. The aim of the present study was therefore to evaluate the impact of Kennedy disease on pituitary gland volume under the hypothesis that endocrinologic changes caused by partial androgen insensitivity may lead to morphologic changes (ie, hypertrophy) of the pituitary gland. Pituitary gland volume was measured in sagittal sections of 3D T1-weighted 3T-MR imaging data of 8 patients with genetically proven Kennedy disease and compared with 16 healthy age-matched control subjects by use of Multitracer by a blinded, experienced radiologist. The results were analyzed by a univariant ANOVA with total brain volume as a covariant. Furthermore, correlation and linear regression analyses were performed for pituitary volume, patient age, disease duration, and CAG repeat expansion length. Intraobserver reliability was evaluated by means of the Pearson correlation coefficient. Pituitary volume was significantly larger in patients with Kennedy disease (636 [±90] mm(3)) than in healthy control subjects (534 [±91] mm(3)) (P = .041). There was no significant difference in total brain volume (P = .379). Control subjects showed a significant decrease in volume with age (r = -0.712, P = .002), whereas there was a trend to increasing gland volume in patients with Kennedy disease (r = 0.443, P = .272). Gland volume correlated with CAG repeat expansion length in patients (r = 0.630, P = .047). The correlation coefficient for intraobserver reliability was 0.94 (P pituitary volume that correlated with the CAG repeat expansion length. This could reflect hypertrophy as the result of elevated gonadotropic hormone secretion caused by the androgen receptor mutation with partial

  17. Thermal Expansion Anomaly Regulated by Entropy

    Science.gov (United States)

    Liu, Zi-Kui; Wang, Yi; Shang, Shunli

    2014-11-01

    Thermal expansion, defined as the temperature dependence of volume under constant pressure, is a common phenomenon in nature and originates from anharmonic lattice dynamics. However, it has been poorly understood how thermal expansion can show anomalies such as colossal positive, zero, or negative thermal expansion (CPTE, ZTE, or NTE), especially in quantitative terms. Here we show that changes in configurational entropy due to metastable micro(scopic)states can lead to quantitative prediction of these anomalies. We integrate the Maxwell relation, statistic mechanics, and first-principles calculations to demonstrate that when the entropy is increased by pressure, NTE occurs such as in Invar alloy (Fe3Pt, for example), silicon, ice, and water, and when the entropy is decreased dramatically by pressure, CPTE is expected such as in anti-Invar cerium, ice and water. Our findings provide a theoretic framework to understand and predict a broad range of anomalies in nature in addition to thermal expansion, which may include gigantic electrocaloric and electromechanical responses, anomalously reduced thermal conductivity, and spin distributions.

  18. Silah, Tasarım ve Kalashnikov Ak-47

    OpenAIRE

    Güneş, Serkan

    2015-01-01

    Silah olgusu insanlığın varoluşundan bu yana saldırmanın ve korunmanın dolayısıyla;yaşamayı sürdürmenin temel araçlarından birisi olarak karşımıza çıkıyor. Medeniyetkavramı ve devletler silah üzerine inşa ediliyor, bekası silah ile korunuyor ve gereklikoşullar oluştuğunda silah vasıtası ile yayılıyor. Güvenlik, huzur ve tehditler için silahlartasarlanıyor, üretiliyor. Silah tasarımı, bekli de insanlık tarihinin en istikrarlı ve en uzuntasarım süreci. Milyonlarca yaratıcı beyin aynı anda öteki...

  19. Tıbbi ve Aromatik Bitkilerin Antibakteriyel Aktivitesi ve Tekstil Sektöründe Kullanımı

    Directory of Open Access Journals (Sweden)

    Hülya KESİCİ GÜLER

    2015-11-01

    Full Text Available Özet: İnsanların doğala yönelmesi ile birlikte tıbbi ve aromatik bitkilere ilgi gün geçtikçe artmaktadır. Tıbbi aromatik bitkiler, hastalıkları önlemek ve iyileştirmek, sağlığı devam ettirmek için insanlık tarihinin başlangıcından beri ilaç olarak kullanılan bitkilerdir. Bu bitkilerin kullanımları ilaç, gıda, meşrubat, kozmetik sanayi, sabun ve parfüm üretiminde sınırlı kalmamış, günümüzde organik tarım ve hayvancılıkta kullanımları artış göstermektedir. Ayrıca günümüzde farklı özelliklerinden dolayı birçok sektörde de kullanılmaya başlanmıştır. Bunlardan bir tanesi de tekstil sektörüdür. Tıbbi ve aromatik bitkiler barındırdıkları antibakteriyel özellik sayesinde sentetik tekstil bitim maddelerine alternatif oluşturmaktadır. Tekstilde kullanılacak antibakteriyel maddelerden beklenen en önemli özelliklerden bir tanesi kullanılan maddenin insan ve çevre sağlığını olumsuz etkilememesi ve tekstil mamulünün diğer özelliklerini olumsuz yönde değiştirmemesidir. Bu nedenle son yıllarda çevre dostu ve doğal esaslı antibakteriyel maddelerin eldesi ve tekstil uygulamalarına olan ilgi hızla artmaktadır. Buna bağlı olarak yapılan çalışmada; tıbbi ve aromatik bitkilerin antibakteriyel aktivitesinin çeşitli yöntemlerle belirlenmesi ve tekstil sektöründe antibakteriyel bitim maddesi olarak kullanımı araştırılmıştır. Anahtar kelimeler: Tıbbi ve aromatik bitkiler, antibakteriyel aktivite, tekstil Antibacterial Activity of Medicinal and Aromatic Plants and Utilization in Textile Industry Abstract: Interest in medicinal and aromatic plants increases along with day by day with natural demands of people. Medicinal and aromatic plants, that are used for protecting and healing illness, and continving the human health, since the beginning of humanity. These plants are used not only in medicine, food, beverage, cosmetic industry, soap and perfume

  20. Residual stress of particulate polymer composites with reduced thermal expansion

    International Nuclear Information System (INIS)

    Nishino, T; Kotera, M; Sugiura, Y

    2009-01-01

    Thermal expansion behavior was investigated for tangusten zirconium phosphate (Zr 2 (WO 4 )(PO 4 ) 2 (ZWP)) particulate filled poly(ether ether ketone) (PEEK) composite. ZWP is known as ceramic filler with a negative thermal expansion. By incorporating ZWP with 40 volume %, the linear thermal expansion coefficient of the PEEK composite was reduced to almost same value (2.53 X 10 -5 K -1 ) with that of aluminum. This decrease was found to be quite effective for the decrease of the residual stress at the interface between aluminum plate and the composite.

  1. Bafa Gölü'nde biyotik ve abiyotik ortamda pestisit ve pcb dağılımı.

    Directory of Open Access Journals (Sweden)

    İdil Pazı

    2015-12-01

    Full Text Available Çalışma kapsamında Bafa Gölü’nden alınan sediment ve kefal balığı (Mugil cephalus, Linnaeus 1758 örneklerinde tarımsal pestisit ve endüstriyel kaynaklı PCB gibi organik kirleticilerin kalıntıları ölçülmüş ve bu bileşiklerin dağılımları, muhtemel kaynakları ve potansiyel biyolojik riskleri incelenmiştir. DDT ve türevleri açısından dünyanın farklı bölgelerindeki göllerin yüzey sedimentleri ile kıyaslandığında Bafa Gölü sedimentlerinde DDT kirlilik seviyesinin oldukça düşük olduğu bulunmuştur. Sedimentte Endrin baskın kirletici olarak belirlenmiştir. Sediment örneklerinde ölçülen DDT ve metabolitleri, Dieldrin, Lindan ve Heptaklor konsantrasyonları sediment kalite indekslerine göre değerlendirildiğinde, kirleticilerin göldeki canlı yaşamına olumsuz bir etkisinin olmadığı belirlenmiştir. ∑PCB konsantrasyonlarının ise göl kıyısında bulunan endüstriyel kuruluşlara yakın istasyonlarda sadece düşük değerli etki sevisini aşıp, diğer tüm istasyonlarda canlılar için risk yaratmayacağı belirlenmiştir. Mugil cephalus karaciğer dokusu için hesaplanan biyota sediment akümülasyon faktörü (BSAF 0.44-3.16 arasında değişmektedir. Bafa Gölü Mugil cephalus örneklerinde ölçülen kirletici konsantrasyonları dikkate alındığında Gıda ve Tarım Kurumu (FAO ve Dünya Sağlık Örgütüne (WHO göre Aldrin, Dieldrin, Endrin, Heptaklor ve DDT türevleri için hesaplanan Günlük Alım Miktarı değerlerinin (EDI Kabul Edilebilir Günlük Alım miktarlarının (ADI oldukça altında kaldığı belirlenmiştir. Ancak, balık örneklerindeki PCB seviyelerinin WHO tarafından belirlenen ADI değerini aştığı saptanmıştır

  2. Modelling The Effects of Aggregate Size on Alkali Aggregate Reaction Expansion

    Directory of Open Access Journals (Sweden)

    N. Z. Sekrane

    2014-06-01

    Full Text Available This work aims at developing models to predict the potential expansion of concrete containing alkali-reactive aggregates. The paper gives measurements in order to provide experimental data concerning the effect of particle size of an alkali-reactive siliceous limestone on mortar expansion. Results show that no expansion was measured on the mortars using small particles (0.5-1.0 mm while the particles (1.0–2.0 mm gave the largest expansions (0.217%. Two models are proposed, the first one studies the correlations between the measured expansions and the size of aggregates, the second one calculates the thickness of the porous zone necessary to take again all the volume of the gel created.

  3. Hygroscopicity and bulk thermal expansion in Y2W3O12

    International Nuclear Information System (INIS)

    Sumithra, S.; Umarji, A.M.

    2005-01-01

    Negative thermal expansion material, Y 2 W 3 O 12 has been synthesized by the solid-state method and bulk thermal expansion of the material has been investigated from 300 to 1100 K. The material reversibly forms a trihydrate composition whose X-ray diffraction pattern can be indexed to an orthorhombic unit cell with a = 10.098(1) A, b = 13.315(3) A, c = 9.691(4) A. The cell volume of the hydrated pattern is 7% smaller than the unhydrated cell volume. According to the dilatometric studies, the material shows a 3-6% increase in the linear strain at about 400 K, which can be attributed to the removal of water. Sintering the material at 1473 K leads to large grain size of >100 μm, which results in a large hysteresis in the bulk thermal expansion behavior. Hot pressing at 1273 K under a uniaxial pressure of 25 MPa results in a fine-grained (2-5 μm) ceramic. Glazing the ceramic prevents moisture pick up and a linear thermal expansion over the entire temperature range 1100-300 K and an average linear thermal expansion co-efficient of -9.65 x 10 -6 /K is observed. The effect of water on the thermal expansion behavior of this system is discussed

  4. Zenginleştirilmiş Ekmeklerde İşleme ve Depolama Sırasında Bazı Vitamin ve Mineral Madde Miktarlarındaki Değişmeler

    Directory of Open Access Journals (Sweden)

    Mehmet Karagül

    2015-02-01

    Full Text Available Bu çalışmada farklı konsantrasyonlarda tiyamin (7.5, 15.0 ve 22.5 mg/kg, riboflavin (7.5, 15.0 ve 22.5 mg/kg, demir (10, 20 ve 30 mg/100 g, magnezyum (50, 75 ve 100 mg/100 ve kalsiyum (200, 300 ve 400 mg/100 g katılanlardan yapılan hamurlarda ve ekmeklerde besin öğelerinin kalma oranı araştırılmıştır. Ekmek pişirmede uygulanan sıcaklık 250 oC ve süre 25 dakikadır. Un tipi ve katkı konsantrasyonu tiyamin, demir ve kalsiyumun ekmekte kalma oranı üzerinde etkili olmuş, riboflavin ve magnezyumu etkilememiştir. Araştırma sonuçlarına göre; una kıyasla hamurda kalma oranı demir için %89.75-107.54, magnezyum için %97.69-106.00, kalsiyum için %99.59-123.67, tiyamin için %42.34-99.59 ve riboflavin için %86.49-97.46’dır. Una göre ekmekte (72 saat sonra kalma oranı ise demir için %76.21-81.97, magnezyum için %74.54-90.03, kalsiyum için %77.56-95.16, tiyamin için %27.82-58.75 ve riboflavin için %59.78-83.78’dir. Demir, kalsiyum ve magnezyumun katkı konsantrasyonu arttıkça ekmek hacmi azalmış, ekmek içi ve aroması bozulmuştur.

  5. İçme ve sulama sularında bor kirliliği ve bor giderme yöntemleri

    Directory of Open Access Journals (Sweden)

    Meltem Bilici Başkan

    2014-03-01

    Full Text Available Periyodik cetvelin 3A grubunda yer alan bor yüksek iyonlaşma potansiyeline sahip olması nedeniyle yarı metal olarak kabul edilir. Yerkabuğundaki ortalama bor konsantrasyonu 10 mg/kg'dır. Bor doğada Ca, Na ve Mg'un tuzları şeklinde bulunur. Yüksek konsantrasyonlarda ve ekonomik boyutlardaki bor yatakları; borun oksijen ile bağlanmış bileşikleri şeklinde daha çok Türkiye ve ABD'nin kurak, volkanik ve hidrotermal aktivitesi olan bölgelerinde bulunmaktadır. Bor, bitkiler için gerekli bir mikro besin elementi olmanın yanı sıra, gerekli tüm besin elementleri içerisinde, eksiklik belirtilerine neden olan miktarı ile toksik etki yapan miktarı, birbirine çok yakın olan tek elementtir. Bor su ortamında genellikle borik asit ve kısmen de borat tuzları formlarında bulunmaktadır. Pek çok endüstride kullanım alanı bulan bor bileşiklerinin endüstriyel gelişmelere bağlı olarak yüzeysel sularda bulunan konsantrasyonu artış göstermektedir. Yüzeysel sularda bulunan bor aynı zamanda evsel atıksulardan da kaynaklanmaktadır. Türkiye'de içme ve sulama sularını en çok kirleten toksik elementlerin başında bor gelmektedir. Bu nedenle bor giderimi hem insan sağlığı açısından hem de sağlıklı tarım ürünü yetiştirilebilmesi açısından oldukça önemlidir. Sulardan bor giderimi için uygulanan temel yöntemler arasında iyon değişimi, ultrafiltrasyon, ters osmoz ve adsorbsiyon gelmektedir.

  6. Thermal expansion measurements by x-ray scattering and breakdown of Ehrenfest's relation in alloy liquids

    International Nuclear Information System (INIS)

    Gangopadhyay, A. K.; Blodgett, M. E.; Johnson, M. L.; Vogt, A. J.; Mauro, N. A.; Kelton, K. F.

    2014-01-01

    Measurements of sharp diffraction peaks as a function of temperature are routinely used to obtain precise linear expansion coefficients of crystalline solids. In this case, the relation between temperature dependent changes in peak position in momentum transfer (q 1 ) and volume expansion is straightforward (Ehrenfest's relation: q 1  = K(2π/d), where K is a constant and d is the interatomic spacing) and the data obtained are usually in close agreement with more direct measurements. With high intensity synchrotron x-ray and spallation neutron sources, it is also possible to accurately measure the positions of the much broader peaks for liquids and glasses. This has led to a debate on whether linear expansion coefficients derived from these data are an accurate representation of the volume expansion coefficients. We present here volume thermal expansion and x-ray diffraction data for a large number of glass-forming alloy liquids acquired in a containerless environment using the beamline electrostatic levitation technique. The data show a large difference in the values obtained from the two different techniques. Moreover, the position of the first peak (q 1 ) in the scattered intensity in the structure factor (S(q)) and the atomic volume v for all liquids follow a simple relationship, v∝(q 1 ) −ε . The exponent, ε = 2.28 (±0.11), is much different from the expected value of 3 from Ehrenfest's relation and shows no temperature dependence over the temperature range of the data collected

  7. VE for Lua game programming

    CERN Document Server

    Mishra, Brij Bhushan

    2013-01-01

    This book follows a tutorial approach with examples and step-by-step instructions to help explain the key concepts of the LÖVE framework as well as everything you need to know about game development using the Lua programming language.LÖVE2d for Lua Game Programming is for anyone who is interested in learning about desktop game development.

  8. Hamilelik ve periodontal hastalık

    OpenAIRE

    Sağlam, Ebru; Saruhan, Nesrin; Çanakçı, Cenk Fatih

    2015-01-01

    Hamileliğe bağlı olarak annede görülen bazı immünolojik değişiklikler enfeksiyonlara yatkınlığı artırmaktadır. Periodontal hastalık, başlıca sebebi mikrobiyal dental plak olan, multifaktöriyel ve çeşitli şiddetlerde görülen yaygın bir hastalıktır. Periodontal hastalığın klinik olarak birçok tanı kriteri bulunmaktadır. Hamilelik ve periodontal enflamasyon arasındaki ilişki uzun yıllardır bilinmektedir. Periodontal hastalık, hamilelerde sistemik durumu etkilemektedir ve fetusa da olumsuz etkile...

  9. Quantum Coherent States and Path Integral Method to Stochastically Determine the Anisotropic Volume Expansion in Lithiated Silicon Nanowires

    Directory of Open Access Journals (Sweden)

    Donald C. Boone

    2017-10-01

    Full Text Available This computational research study will analyze the multi-physics of lithium ion insertion into a silicon nanowire in an attempt to explain the electrochemical kinetics at the nanoscale and quantum level. The electron coherent states and a quantum field version of photon density waves will be the joining theories that will explain the electron-photon interaction within the lithium-silicon lattice structure. These two quantum particles will be responsible for the photon absorption rate of silicon atoms that are hypothesized to be the leading cause of breaking diatomic silicon covalent bonds that ultimately leads to volume expansion. It will be demonstrated through the combination of Maxwell stress tensor, optical amplification and path integrals that a stochastic analyze using a variety of Poisson distributions that the anisotropic expansion rates in the <110>, <111> and <112> orthogonal directions confirms the findings ascertained in previous works made by other research groups. The computational findings presented in this work are similar to those which were discovered experimentally using transmission electron microscopy (TEM and simulation models that used density functional theory (DFT and molecular dynamics (MD. The refractive index and electric susceptibility parameters of lithiated silicon are interwoven in the first principle theoretical equations and appears frequently throughout this research presentation, which should serve to demonstrate the importance of these parameters in the understanding of this component in lithium ion batteries.

  10. Research on a novel DDC-based capacity controller for the direct-expansion variable-air-volume A/C system

    Energy Technology Data Exchange (ETDEWEB)

    Chen Wu, E-mail: chenwu73@263.ne [School of Marine Engineering, Jimei University, Xiamen, Fujian Province 361021 (China); Deng Shiming [Department of Building Services Engineering, The Hong Kong Polytechnic University, Kowloon (Hong Kong)

    2010-01-15

    A direct-expansion (DX) variable-air-volume (VAV) air-conditioning (A/C) system consists of a VAV air-distribution sub-system and a DX refrigeration plant. This paper reports in detail on a novel capacity controller developed for the DX VAV A/C system to regulate its compressor speed and hence its cooling capacity. The capacity controller consisted of both a numerical calculation algorithm (NCA), which was fundamentally based on the principle of energy balance using a number of real-time measured system's operating parameters, and a dead-band for decoupling the control actions from both the capacity controller and a conventional PI feedback controller for regulating the opening of an electronic expansion valve (EEV) in the refrigeration plant. To study the feasibility of the capacity controller, an experimental rig for the DX VAV A/C system having two conditioned spaces was built and experimental tests were carried out. The test results showed that using the capacity controller, the cooling capacity of the system's refrigeration plant can be accurately and continuously regulated and the supply air temperature well maintained at its desired value. The desirable independent zoning-control for space air temperatures can be successfully achieved by the DX VAV A/C system and the control performance for air temperatures in the conditioned space was highly satisfactory.

  11. Research on a novel DDC-based capacity controller for the direct-expansion variable-air-volume A/C system

    Energy Technology Data Exchange (ETDEWEB)

    Chen, Wu [School of Marine Engineering, Jimei University, Xiamen, Fujian Province 361021 (China); Deng, Shiming [Department of Building Services Engineering, The Hong Kong Polytechnic University, Kowloon (China)

    2010-01-15

    A direct-expansion (DX) variable-air-volume (VAV) air-conditioning (A/C) system consists of a VAV air-distribution sub-system and a DX refrigeration plant. This paper reports in detail on a novel capacity controller developed for the DX VAV A/C system to regulate its compressor speed and hence its cooling capacity. The capacity controller consisted of both a numerical calculation algorithm (NCA), which was fundamentally based on the principle of energy balance using a number of real-time measured system's operating parameters, and a dead-band for decoupling the control actions from both the capacity controller and a conventional PI feedback controller for regulating the opening of an electronic expansion valve (EEV) in the refrigeration plant. To study the feasibility of the capacity controller, an experimental rig for the DX VAV A/C system having two conditioned spaces was built and experimental tests were carried out. The test results showed that using the capacity controller, the cooling capacity of the system's refrigeration plant can be accurately and continuously regulated and the supply air temperature well maintained at its desired value. The desirable independent zoning-control for space air temperatures can be successfully achieved by the DX VAV A/C system and the control performance for air temperatures in the conditioned space was highly satisfactory. (author)

  12. Research on a novel DDC-based capacity controller for the direct-expansion variable-air-volume A/C system

    International Nuclear Information System (INIS)

    Chen Wu; Deng Shiming

    2010-01-01

    A direct-expansion (DX) variable-air-volume (VAV) air-conditioning (A/C) system consists of a VAV air-distribution sub-system and a DX refrigeration plant. This paper reports in detail on a novel capacity controller developed for the DX VAV A/C system to regulate its compressor speed and hence its cooling capacity. The capacity controller consisted of both a numerical calculation algorithm (NCA), which was fundamentally based on the principle of energy balance using a number of real-time measured system's operating parameters, and a dead-band for decoupling the control actions from both the capacity controller and a conventional PI feedback controller for regulating the opening of an electronic expansion valve (EEV) in the refrigeration plant. To study the feasibility of the capacity controller, an experimental rig for the DX VAV A/C system having two conditioned spaces was built and experimental tests were carried out. The test results showed that using the capacity controller, the cooling capacity of the system's refrigeration plant can be accurately and continuously regulated and the supply air temperature well maintained at its desired value. The desirable independent zoning-control for space air temperatures can be successfully achieved by the DX VAV A/C system and the control performance for air temperatures in the conditioned space was highly satisfactory.

  13. EKSENEL PİSTONLU POMPA VE MOTORLARDA KAYICI PAPUÇ PERFORMANS ARAŞTIRMASI-AKIŞ VE VİSKOZ GÜÇ KAYBI

    Directory of Open Access Journals (Sweden)

    A. Osman KURBAN

    1997-01-01

    Full Text Available Bu çalışmada, hidrostatik-hidrodinamik yatakların iyi bir uygulama alanı olan, eğik plakalı eksenel pistonlu pompa ve motorların performansı üzerinde etkili olan kayıcı pabuçlar incelenmiştir. Bununla ilgili olarak viskoz moment kayıpları, viskoz akışkan kaçağı ve güç kayıp denklemleri elde edilip, değişik çalışma ortamlarında bu karakteristik parametrelerin değişimi ve mukayesesi deneysel olarak incelenmiştir.

  14. Yeni heterosiklik disazo boyarmaddelerin sentezi ve spektroskopik özelliklerinin incelenmesi

    OpenAIRE

    Demirçalı, Aykut

    2012-01-01

    Bu çalışmada, ilk etapta anilin ve anilin türevleri 3-aminokrotononitril ile kenetlenmiş daha sonra hidrazin monohidrat ve fenil hidrazin ile halka kapama reaksiyonu sonucu 5-amino-4-arilazo-3-metil-1H-pirazol (2a-2e) ve 5-amino-4-arilazo-3-metil-1-fenil-pirazol (3a-3e) türevi mono azo boyarmaddeler sentezlenmiştir. İkinci aşamada sentezlenen bu bileşikler önce diazolanmış sonrasında etil benzoil asetat ile kenetlenmiş ve yine hidrazin mono hidrat ve fenil hidrazin ile halka kapama reaksiyonu...

  15. ENDODONTİDE FLARE-UP’IN ÖNLENMESİ VE TEDAVİSİ

    OpenAIRE

    GÜLER, Buğra; AYDEMİR, Hikmet

    2015-01-01

    ÖZETAğrı ve ağrı korkusu hasta ve hekim ilişkisinin ciddi problemlerinden birisidir. Endodontik tedavi sırasında veya sonrasında meydana gelen ağrı şikâyetlerinin azaltılması için çeşitli tedavi şekilleri ve önlemler mevcuttur. Bu tedavi şekilleri, dişin oklüzyondan düşürülmesi, premedikasyon, drenajın sağlanması, kanal içi ve sistemik medikament işlemlerini içermektedir. Bu derlemede, flare-up meydana geldiğinde hastanın nasıl yönetilmesi gerektiğinin ve flare-up’ın önlenmesi ve tedavisi içi...

  16. Intrinsic thermal expansion of crystal defects

    International Nuclear Information System (INIS)

    Ganne, J.-P.

    1981-02-01

    Although the phenomenon of thermal expansion has long been known, the intrinsic thermal expansion coefficient (ITEC) βsub(d) of a point defect, derived from its formation volume vsub(d), has never been measured directly. The differential dilatometer by interferometry built by ASTY and GILDER is described. It has allowed βsub(d) to be measured for several defects. Vacancies and small interstitial loops were produced in aluminium by low temperature (20 K) fast neutron irradiation followed by an anneal up to the beginning of stage III (160 K). The very high value of the measured ratio βsub(d)/β 0 (12+-4) is comparable with a lattice statics calculated (42) value (11.5 0 [fr

  17. Allometric relationship and biomass expansion factors (BEFs) for above- and below-ground biomass prediction and stem volume estimation for ash (Fraxinus excelsior L.) and oak (Quercus robur L.)

    Czech Academy of Sciences Publication Activity Database

    Krejza, Jan; Světlík, J.; Bednář, P.

    2017-01-01

    Roč. 31, č. 4 (2017), s. 1303-1316 ISSN 0931-1890 R&D Projects: GA MŠk(CZ) LO1415 Institutional support: RVO:67179843 Keywords : floodplain forest * root biomass * leaf biomass * branch biomass * shoot biomass * Allometry * stem volume * biomass expansion factor Subject RIV: GK - Forestry OBOR OECD: Forestry Impact factor: 1.842, year: 2016

  18. Thermal expansion model for multiphase electronic packaging materials

    International Nuclear Information System (INIS)

    Allred, B.E.; Warren, W.E.

    1991-01-01

    Control of thermal expansion is often necessary in the design and selection of electronic packages. In some instances, it is desirable to have a coefficient of thermal expansion intermediate between values readily attainable with single or two phase materials. The addition of a third phase in the form of fillers, whiskers, or fibers can be used to attain intermediate expansions. To help design the thermal expansion of multiphase materials for specific applications, a closed form model has been developed that accurately predicts the effective elastic properties of isotropic filled materials and transversely isotropic lamina. Properties of filled matrix materials are used as inputs to the lamina model to obtain the composite elastic properties as a function of the volume fraction of each phase. Hybrid composites with two or more fiber types are easily handled with this model. This paper reports that results for glass, quartz, and Kevlar fibers with beta-eucryptite filled polymer matrices show good agreement with experimental results for X, Y, and Z thermal expansion coefficients

  19. Tekirdağ İlinde Yetiştirilen Bazı Sebze ve Meyvelerde Nitrat ve Nitrit Miktarları Üzerinde Araştırmalar

    Directory of Open Access Journals (Sweden)

    Harun Dıraman

    2015-02-01

    Full Text Available Meyve ve sebzelerin doğal yapılarında bulunan nitrat ve nitritin miktarları, günümüzde çevre kirlenmesinin gıdalar üzerindeki etkisini gösteren önemli parametrelerdendir. Nitrat ve nitritler gerekli ortamı buldukları zaman kanserojen bileşenlere dönüşmektedirler. Nitrat ve nitritin tayininde çeşitli kimyasal yöntemler kullanılmaktadır. Bu araştırmada ISO tarafından meyve ve sebzelerde nitrat ve nitrit belirlenmesinde referans metot olarak verilen moleküler absorpsiyon spektrofotometrik metot kullanılmıştır.Tekirdağ ilinin farklı yerleşim birimlerinden toplanan toplam 96 örnek üzerinde çalışılmıştır. Ispanak, marul, taze fasulye, patates, elma ve üzümde mg/kg taze ağırlık üzerinden belirlenen ortalama nitrat değerleri sırası ile 362.5, 685.6, 168.6, 777.9, 18.1, 16.6 olmuştur. Nitrit miktarları ise  çok düşük ve önemsiz düzeyde bulunmuştur. Örnekler üzerindeki nitrat ve nitrit miktarlarıyla ilgili istatistiki değerlendirmede  yapılan gruplar arasında önemli farklılık olduğu bulunmuştur. Örneklerin nitrat miktarlarının Türk Gıda Kodeksi tarafından izin verilen  maksimum değerlerin altında ve düşük  olduğu görülmüştür.

  20. Photoexcitation-induced processes in amorphous semiconductors

    Energy Technology Data Exchange (ETDEWEB)

    Singh, Jai [School of Engineering and Logistics, Charles Darwin University, Darwin, NT 0909 (Australia)]. E-mail: jai.singh@cdu.edu.au

    2005-07-30

    Theories for the mechanism of photo-induced processes of photodarkening (PD), volume expansion (VE) in amorphous chalcogenides are presented. Rates of spontaneous emission of photons by radiative recombination of excitons in amorphous semiconductors are also calculated and applied to study the excitonic photoluminescence in a-Si:H. Results are compared with previous theories.

  1. Photoexcitation-induced processes in amorphous semiconductors

    International Nuclear Information System (INIS)

    Singh, Jai

    2005-01-01

    Theories for the mechanism of photo-induced processes of photodarkening (PD), volume expansion (VE) in amorphous chalcogenides are presented. Rates of spontaneous emission of photons by radiative recombination of excitons in amorphous semiconductors are also calculated and applied to study the excitonic photoluminescence in a-Si:H. Results are compared with previous theories

  2. Synthesis of Expansive Mortar Developed in Laboratory for Dismounting of Ornamental Rocks

    International Nuclear Information System (INIS)

    Lucena D V; Campos D B C; Lira H L; Neves G A

    2011-01-01

    The expansive mortar is constituted by a mixture of watery phase with an agent expander, when hydrated, presents volume increase and the generation of fictions in the rock due to generated pressure. The objective of this work is to synthecize expansive mortar that they present enough expansive pressure for the dismounting of granite and marble. They had been used as raw materials: carbonate of calcium, Portland cement and additives for control of the expansion. The formularizations had been synthecized on the basis of the chemical analysis of a mortar commercial and characterized by XRD, laser particle size measurements and evaluation of expansive pressure. All the developed formularizations had presented similar characteristics to the ones of the commercial mortar.

  3. Free volume dilatation in polymers by ortho-positronium

    DEFF Research Database (Denmark)

    Winberg, P.; Eldrup, Morten Mostgaard; Maurer, F.H.J.

    2012-01-01

    The possibility of positronium induced free volume cavity expansion in some polymers above the glass transition temperature was investigated using experimental positron annihilation lifetime data from the literature for polydimethylsiloxane, polyisobutylene, and polybutadiene as function of tempe......The possibility of positronium induced free volume cavity expansion in some polymers above the glass transition temperature was investigated using experimental positron annihilation lifetime data from the literature for polydimethylsiloxane, polyisobutylene, and polybutadiene as function...

  4. Yaşam Bilimleri ve Biyoteknoloji

    Directory of Open Access Journals (Sweden)

    Rasime DEMİREL

    2010-10-01

    Full Text Available Eskişehir (Türkiye’deki farklı marketlerden toplanmış olan şişelenmiş doğal ve mineral suların mikrobiyal kalitesi incelenmiştir. Membran filtrasyon tekniği uygulanarak su örneklerinin kalitesi; toplam koliform, Escherichia coli, Enterococcus spp., Aeromonas hydrophila’nın varlığı ve miktarı yönünden analiz edilmiştir. Aerobik bakteriler 22 ve 37 ºC’de inkübasyonu sonucunda ml’deki heterotrofik bakteri sayısı (HPC olarak belirlenmiştir. Şişelenmiş mineral su örneklerinde Bacillus türleri belirlenirken, şişelenmiş içme suyu örneklerinde herhangi bir bakteri ya da kontaminasyon bulunmamıştır

  5. Acute effects of volume-oriented incentive spirometry on chest wall volumes in patients after a stroke.

    Science.gov (United States)

    Lima, Illia Ndf; Fregonezi, Guilherme Af; Melo, Rodrigo; Cabral, Elis Ea; Aliverti, Andrea; Campos, Tânia F; Ferreira, Gardênia Mh

    2014-07-01

    The aim of the present study was to assess how volume-oriented incentive spirometry applied to patients after a stroke modifies the total and compartmental chest wall volume variations, including both the right and left hemithoraces, compared with controls. Twenty poststroke patients and 20 age-matched healthy subjects were studied by optoelectronic plethysmography during spontaneous quiet breathing (QB), during incentive spirometry, and during the recovery period after incentive spirometry. Incentive spirometry was associated with an increased chest wall volume measured at the pulmonary rib cage, abdominal rib cage and abdominal compartment (P = .001) and under 3 conditions (P spirometry, and postincentive spirometry, respectively. Under all 3 conditions, the contribution of the abdominal compartment to VT was greater in the stroke subjects (54.1, 43.2, and 48.9%) than in the control subjects (43.7, 40.8, and 46.1%, P = .039). In the vast majority of subjects (13/20 and 18/20 during QB and incentive spirometry, respectively), abdominal expansion precedes rib cage expansion during inspiration. Greater asymmetry between the right and left hemithoracic expansions occurred in stroke subjects compared with control subjects, but it decreased during QB (62.5%, P = .002), during incentive spirometry (19.7%), and postincentive spirometry (67.6%, P = .14). Incentive spirometry promotes increased expansion in all compartments of the chest wall and reduces asymmetric expansion between the right and left parts of the pulmonary rib cage; therefore, it should be considered as a tool for rehabilitation. Copyright © 2014 by Daedalus Enterprises.

  6. Review article: volume expansion in patients with cirrhosis

    DEFF Research Database (Denmark)

    Henriksen, Jens Henrik; Kiszka-Kanowitz, Marianne; Bendtsen, Flemming

    2002-01-01

    Adequate size and distribution of the circulating medium are important for cardiovascular function, tissue oxygenation, and fluid homoeostasis. Patients with cirrhosis have cardiovascular dysfunction with a hyperkinetic systemic circulation, abnormal distribution of the blood volume, vasodilation...

  7. Addison hastalığı ve gebelik

    OpenAIRE

    Bayrak, Z; Turan, V; Demirtaş, G; Erdoğan, M; Aşkar, N

    2011-01-01

    Primer adrenal yetmezlik nadir görülen bir endokrinolojik hastalıktır. Çoğu idiopatiktir. Tip 1 diabetes mellitus, hipertiroidizm, hipotiroidizm, pernisiyöz anemi gibi otoimmun hastalıklarla ilişkilidir. Yirmi sekiz yaşında 18 yıldır Addison hastalığı nedeni ile tedavi gören ve gebelik istemi olan olguyu gebeliğin ilk haftalarından doğuma ve puerperal döneme kadar takip ettik. Endokrinoloji kliniği ile birlikte takip ettiğimiz hastada kortikosteroid tedavisi ile antenatal ve postnatal dönemde...

  8. A quantitative analysis of craniopharyngioma cyst expansion during and after radiation therapy and surgical implications.

    Science.gov (United States)

    Lamiman, Kelly; Wong, Kenneth K; Tamrazi, Benita; Nosrati, Jason D; Olch, Arthur; Chang, Eric L; Kiehna, Erin N

    2016-12-01

    OBJECTIVE When complete resection of craniopharyngioma is not achievable or the sequelae are prohibitive, limited surgery and radiation therapy have demonstrated excellent local disease control while minimizing treatment-related sequelae. When residual tissue exists, there is a propensity for further cyst development and expansion during and after radiation therapy. This can result in obstructive hydrocephalus, visual changes, and/or clinical decline. The authors present a quantitative analysis of cyst expansion during and after radiotherapy and examine how it affected subsequent management. METHODS The authors performed an institutional review board-approved retrospective study of patients with histologically confirmed craniopharyngioma treated between 2000 and 2015 with surgery and intensity-modulated radiation therapy (IMRT) at a single institution. Volumetric measurements of cyst contours were generated by radiation oncology treatment planning software postoperatively, during IMRT, and up to 12 months after IMRT. Patient, tumor, and treatment-related variables were collected until the last known follow-up and were analyzed. RESULTS Twenty-seven patients underwent surgery and IMRT. The median total radiation dose was 54 Gy. Of the 27 patients, 11 patients (40.7%) demonstrated cyst expansions within 1 year of IMRT. Of note, all tumors with cyst expansion were radiographically Puget Grade 2. Maximal cyst expansion peaked at 4.27 months following radiation therapy, with a median volume growth of 4.1 cm 3 (mean 9.61 cm 3 ) above the postoperative cyst volume. Eight patients experienced spontaneous cyst regression without therapeutic intervention. Three patients experienced MRI-confirmed cyst enlargement during IMRT, all of whom required adaptive planning to ensure adequate coverage of the entire tumor volume. Two of these 3 patients required ventriculoperitoneal shunt placement and additional intervention. One underwent additional resection, and the other had

  9. Bir Buzağıda Notomeli (Notomelia) ve Pakomeli (Phocomelia) Olgusu

    OpenAIRE

    HAYAT, Ali

    2013-01-01

    Bu vaka takdiminde, 15 günlük dişi melez bir buzağıda notomeli ve pakomeli anomalisi klinik ve radyolojik olarak değerlendirildi. Notomelie ve pakomeli olgusunun buzağılarda çok nadir görülmesi ve ilginç olmasından dolayı bu vaka rapor edilmiştir.

  10. Urfa Peynirlerinin Mikrobiyolojik, Kimyasal ve Duyusal Niteliklerinin Saptanması

    Directory of Open Access Journals (Sweden)

    Atilla Yetişmeyen

    2015-02-01

    Full Text Available Bu araştırmada Ankara İli merkezinde satışa sunulan Urfa peynirlerinin mikrobiyolojik, kimyasal ve duyusal özellikleri belirlenmiştir. Mikrobiyolojik incelemeler sonucunda, örneklerde ortalama olarak; 1,0x109 kob/g TAMB (toplam aerobik mezofil bakteri, 1,0x107 kob/g maya ve küf, 3,5x106 EMS/g koliform bakteri, 1,1 x106 EMS/g E. coli ve 1,3x103 kob/g S. aureus olduğu tespit edilmiştir. Elde edilen bulgular, Urfa peynirlerinin üretiminde ve pazarlanması sırasında hijyenik kurallara uyulmadığını ve kötü bir mikrobiyolojik kaliteye sahip olduğunu göstermektedir. Kimyasal analizler sonucu örneklerin kurumadde, yağ, kurumaddede yağ, protein, tuz, kurumaddede tuz, kül, titrasyon asilliği (yüzde laktik asit cinsinden, pH, toplam azot, suda eriyen azot, olgunlaşma katsayısı ve protein olmayan azot değerleri sırasıyla % 48,33, % 22,96, % 47,48, % 17,53, % 6,80, % 17,53, % 2,107, % 1,23, 5,44 pH, % 2,747, % 0,411, % 15,25 ve % 0,26 olarak belirlenmiştir. Duyusal nitelikler bakımından ise; peynirlerin 100 puan üzerinden ortalama 53,71 puan aldıkları tespit edilmiştir. Elde edilen sonuçlardan Urfa peynirlerinin standart bir kalitede olmadığı, üretiminde ve pazarlanmasında hijyenik kurallara uyulmadığı anlaşılmaktadır.

  11. Surke'nin Bazı Kimyasal ve Mikrobiyolojik Kalite Nitelikleri

    Directory of Open Access Journals (Sweden)

    Ufuk Kamber

    2015-02-01

    Full Text Available Bu çalışma, Hatay ilinde tüketilen ve halk arasında Surke peyniri olarak kabul edilen süt ürününün bazı kimyasal ve mikrobiyolojik özeliklerini ortaya koymak ve Surke' yi tanıtmak amacıyla yapılmıştır. On örnek üzerinde yapılan analizlerde Surke peynirinde ortalama mikrobiyolojik analiz sonuçları sırasıyla toplam aerob mezofil bakteri; 6.5x108 kob/g, laktobasiller 4.4x107kob/g, laktokoklar 2.8x102 kob/g, mikrokok ve stafilokoklar 2.5x102 kob/g, enterobakteriler 3.5x102 kob/g, koliform grubu bakteriler <2.0x102kob/g, ve maya/küf ise 2.7x105 kob/g düzeyinde izole edilmiştir. Kimyasal analiz bulgularına göre ortalama; peynirlerde kuru madde miktarı % 52.8, yağ % 11.0, tuz % 8.1 ve asitlik laktik asit (LA cinsinden % 2.1 olarak saptanmıştır.

  12. Cabernet Sauvignon ve Merlot Şarapların Resveratrol Düzeyleri ve Ekolojik Koşulların Etkileri

    OpenAIRE

    Belkıs Çaylak Adıgüzel; Nedim Çetinkaya; Ufuk Yücel

    2015-01-01

    Fitoaleksinler bitkilerde patojen enfeksiyonuna bir reaksiyon olarak veya çeşitli biyotik ve abiyotik tetikleyicilerin etkisi sonucu oluşan fenolik madde karakterli, düşük molekül ağırlıklı antimikrobiyal bileşiklerdir. Resveratrol (trans–3,5,4’-trihidroksistilben) de bir fitoaleksin olup, asma (Vitis vinifera), yer fıstığı (Arachis hypogaea) ve diğer pek çok bitki türünde yaprak veya diğer organlarda yüksek miktarlarda bulunabilmektedir. Resveratrol asmada gövde, sürgün ve yapraklar yanında,...

  13. Semiyoloji ve Semiyotik Üzerine Düşünceler

    OpenAIRE

    Çiçek, Mehmet

    2016-01-01

    Türkçede Göstergebilim diye tek sözcükle karşılanan kavram Fransızca ve İngilizcede iki sözcükle karşılanmaktadır: Semiyoloji ve Semiyotik (Fr. Sémiologie; Sémiotique / İng. Semiology; Semiotics). Semiyoloji ve Semiyotik aynı şeyler midir, farklı şeyler mi? Biz bu kavramların eş anlamlı değil; olsa olsa yakın anlamlı olabileceklerini düşünüyoruz. Bu makalede bu kavramlar ve bu kavramlara ilişkin görüşler irdelenecektir.

  14. Ekşi Hamurlardan Laktik Asit Bakterileri ve Mayaların İzolasyonu ve Tanımlanması

    OpenAIRE

    Bakırcı, Fatih; Köse, Ergun

    2017-01-01

    Gıda tüketiminde önemli bir yere sahip olanekmeğin, son yıllarda raf ömrünü uzatmak ve besin kalitesini arttırmak içinzengin aroma ve doğal mikrofloraya sahip ekşi hamur ile üretimleri tercihedilmektedir. Bu çalışmada, İzmir ilinde bulunan 10 farklı yerel fırından alınan10 farklı ekşi hamur örneğinden izole edilen laktik asit bakteri (LAB) ve mayasuşlarının tanımlanması amaçlanmıştır. Ekşi hamur örneklerinden izole edilenmikroorganizmalar biyokimyasal özelliklerine göre Vitek 2 Compact (Biome...

  15. FvVE1 Regulates Biosynthesis of Fumonisins and Fusarins in Fusarium verticillioides

    Science.gov (United States)

    MYUNG, KYUNG; LI, SHAOJIE; BUTCHKO, ROBERT A.E.; BUSMAN, MARK; PROCTOR, ROBERT H; ABBAS, HAMED K.; CALVO, ANA M.

    2009-01-01

    The veA gene positively regulates sterigmatocystin production in Aspergillus nidulans and aflatoxin production in A. parasiticus and A. flavus. Whether veA homologs have a role in regulating secondary metabolism in other fungal genera is unknown. In this study, we examined the role of the veA homolog, FvVE1, on production of two mycotoxin families, fumonisins and fusarins, in the important corn pathogen F. verticillioides. We found that FvVE1 deletion completely suppressed fumonisin production on two natural substrates, corn and rice. Furthermore, our results revealed that FvVE1 is necessary for the expression of the pathway-specific regulatory gene FUM21 and structural genes in the fumonisin biosynthetic gene (FUM) cluster. FvVE1 deletion also blocked production of fusarins. The effects of FvVE1 deletion on the production of these toxins were found to be the same in two separate mating types. Our results strongly suggest that FvVE1 play an important role in regulating mycotoxin production in F. verticillioides. PMID:19382792

  16. Effects of current density and electrolyte temperature on the volume expansion factor of anodic alumina formed in oxalic acid

    International Nuclear Information System (INIS)

    Zhou, F.; Baron-Wiecheć, A.; Garcia-Vergara, S.J.; Curioni, M.; Habazaki, H.; Skeldon, P.; Thompson, G.E.

    2012-01-01

    The formation of porous anodic alumina in 0.4 M oxalic acid is investigated over a range of current density and electrolyte temperature using sputtering-deposited substrates containing tungsten tracer layers. The findings reveal volume expansion factors and efficiencies of film growth that increase with the increase of the current density and decrease of the temperature. Pore generation by the flow of the anodic alumina in the barrier layer toward the pore walls is proposed to dominate at relatively high current densities (above ∼2 mA cm −2 ), with tungsten tracer species being retained within films. Conversely, losses of tungsten species occur at lower current densities, possibly due to increased field-assisted ejection of Al 3+ ions and/or field-assisted dissolution of the anodic alumina.

  17. Süt ve Ürünlerinde CO2 Uygulamaları – II: Çiğ ve Pastörize Süt

    Directory of Open Access Journals (Sweden)

    Enes Dertli

    2015-02-01

    Full Text Available Ürünlerin üretiminde hammaddeden kaynaklanan başlangıç bakteriyel yükün azaltılması, pastörizasyon sisteminin geliştirilmesi ve üretim işlemlerinden önceki kontaminasyonun önlenmesi gibi uygulamalar raf ömrünün uzatılmasında etkilidir. Karbon dioksit doğal olarak meydana gelen bir süt bileşenidir ve kesin mekanizması henüz anlaşılamamasına rağmen, ürünlerde bazı bozulma oluşturan mikroorganizmalara karşı inhibitör etkilidir. Uygulamada kullanılan yeni CO2 teknolojileri çiğ ve pastörize sütü içeren sütçülük ürünlerinde farklılığın artırılması, raf ömrünün ve kalitenin yükseltilmesi amacıyla sürekli geliştirilmektedir. Bu çalışmada CO2 kullanılarak çiğ ve pastörize sütün kalitesinin geliştirilmesi konusunda geçmişteki ve günümüzdeki araştırmalar detaylı olarak irdelenmiştir.

  18. Metil ve Etil Ester Kullanılan Bir Common-Rail Dizel Motorda Performans, Yanma ve Enjeksiyon Karakteristiklerinin Karşılaştırılması

    Directory of Open Access Journals (Sweden)

    Ertan ALPTEKİN

    2017-02-01

    Full Text Available Biyodizel, dünyada kullanımı yaygınlaşan yenilebilir ve alternatif bir dizel yakıtıdır. Biyodizel üretiminde kullanılan alkol büyük önem arz etmekte ve üretilen biyodizelin yakıt özelliklerini doğrudan etkilemektedir. Farklı yakıt özellikleri, dizel motorlarda farklı yakıt enjeksiyon ve yanma karakteristiklerine sebep olabilmektedir. Bu nedenle bu çalışmada, metanol ve etanol kullanılarak üretilen iki farklı ester yakıtı ve saf motorin, common-rail yakıt enjeksiyon sistemine sahip bir dizel motorda üç farklı motor yükü (50 Nm, 100 Nm ve 150 Nm ve 2000 dev/dk sabit motor devrinde deney yakıtı olarak kullanılmıştır. Bu yakıtların performans, yanma ve yakıt enjeksiyon analizi karşılaştırmalı olarak gerçekleştirilmiştir. Deney sonuçlarına göre, etil ve metil ester kullanımıyla özgül yakıt tüketimi (ÖYT motorine kıyasla artış göstermiştir. Etil ve metil ester yakıtlarının silindir içi basıncı ve ısı yayılımı değerleri tüm deney şartlarında motorine kıyasla daha yüksek olmuştur. Yakıt enjeksiyon karakteristikleri, yakıt tipi ve motor yüküne bağlı olarak farklılık göstermiştir.

  19. Biyodizel ve Karışımlarının Kullanıldığı bir Dizel Motorda Performans ve Emisyon Analizi

    Directory of Open Access Journals (Sweden)

    Ahmet Necati ÖZSEZEN

    2009-02-01

    Full Text Available Bu çalışmada, atık palmiye yağı kökenli biyodizel ve petrol kökenli dizel yakıtı (PKDY ile karışımlarının, bir dizel motordaki performans ve emisyon karakteristikleri üç boyutlu haritalar üzerinden analiz edilmiştir. Biyodizel ve karışımlarının performans ve emisyon karakterlerini belirlemek amacıyla, motor tam yük ve değişik devir testlerine tabi tutulmuştur. Analiz sonucunda, karışımdaki biyodizel oranı arttıkça PKDY'a göre özgül yakıt tüketiminde artış olduğu, motorun döndürme momentinde ise azalma meydana geldiği tespit edilmiştir. Emisyon analizi sonucunda ise, karışımdaki biyodizel oranı ile ilişkili olarak PKDY'a kıyasla yanmamış hidrokarbon (HC, karbon monoksit (CO ve duman koyuluğu emisyonlarında iyileşmeler olduğu, bununla birlikte karbon dioksit (CO2 ve azot oksit (NOx emisyonlarının motor devrine göre kararlı bir yapı sergilemediği belirlenmiştir.

  20. Kefir ve Sağlık

    OpenAIRE

    DAYISOYLU, Kenan Sinan; KÖROĞLU, Özge; BAKIR, Esra; ULUDAĞ, Günsel; KÖROĞLU, Sedat

    2015-01-01

    Özet: Son yıllarda toplumlar beslenme konusunda giderek daha bilinçli hale gelmektedir. Beslenme konusunda temel talep olan sağlıklı ve güvenli gıdalar tüketebilme isteğinin yanında; insan sağlığına ek faydalar sağlayan, hastalıklardan koruma potansiyeli olan ve fonksiyonel gıda olarak adlandırılan ürünlere ulaşma isteği de giderek artmaktadır. Kefir, fonksiyonel gıdalardan probiyotikler alt kolunun önemli bir üyesi olup, içeriğinde birçok faydalı maya ve bakteri bulunduran, son yıllarda popü...

  1. Tulum Peynirlerinden izole Edilen Lactococcus lactis subsp. lactis YBML9 ve

    Directory of Open Access Journals (Sweden)

    Yasin TUNCER

    2009-04-01

    Full Text Available Bu çalısmanın amacı tulum peynirlerinden izole edilen Lactococcus lactis suslarının fenotipik tanısı ve bu suslar tarafından üretilen bakteriyosinlerin kısmi karakterizasyonlarıdır. Bu amaçla Türkiye'nin sekiz farklı ilinden (Ankara, Antalya, Burdur, Denizli, Erzincan, Isparta, İstanbul ve İzmir yöresel pazarlardan toplanan 60 adet tulum peyniri örneginden 40 adet Lactococcus lactis susu (31 adet L. lactis subsp. lactis ve 9 adet L. lactis subsp. cremoris izole edildi. 40 adet L. lactis susu içerisinden, 2 adet L. lactis subsp. lactis (YBML9 ve YBML21 susu bakteriyosin üretme yeteneginde bulundu. L. lactis subsp. lactis YBML9 ve YBML21 susları tarafından üretilen bakteriyosinler, farklı enzim, pH ve sıcaklık uygulamaları sonucu; sırasıyla nisin ve laktisin 481 olarak tanımlandı.

  2. ERZURUM ŞARTLARINDA DİKİM ZAMANI VE TEPE ALMANIN PATATESTE VERİM VE ÇEŞİTLİ ÖZELLİKLERİNE ETKİSİ /

    OpenAIRE

    Şenol, Sabahattin

    2010-01-01

    ÖZETErzurum Ekolojik şartlarında dikim ve tepe alma zamanmm patatesteverime ve diğer bazı agronomik karekterlere etkisini tesbitetmek için bu çalışma yapılmış, erkenci ve geç olgunlaşan 34/962 ve49/962 çeşitler bu denemeye alınmıştır. Neticede, en fazıa verim enerken dikim zamanı olarak tayin ediıen 13 Mayıs tarihinde a.ltlnmış,tepe aımanm· veya sürgün öıdürmenin önemli etkisi g&ou...

  3. Variations in gastric emptying of liquid elicited by acute blood volume changes in awake rats

    Directory of Open Access Journals (Sweden)

    Gondim F. de-A.A.

    1998-01-01

    Full Text Available We have observed that acute blood volume expansion increases the gastroduodenal resistance to the flow of liquid in anesthetized dogs, while retraction decreases it (Santos et al. (1991 Acta Physiologica Scandinavica, 143: 261-269. This study evaluates the effect of blood volume expansion and retraction on the gastric emptying of liquid in awake rats using a modification of the technique of Scarpignato (1980 (Archives Internationales de Pharmacodynamie et de Therapie, 246: 286-294. Male Wistar rats (180-200 g were fasted for 16 h with water ad libitum and 1.5 ml of the test meal (0.5 mg/ml phenol red solution in 5% glucose was delivered to the stomach immediately after random submission to one of the following protocols: 1 normovolemic control (N = 22, 2 expansion (N = 72 by intravenous infusion (1 ml/min of Ringer-bicarbonate solution, volumes of 1, 2, 3 or 5% body weight, or 3 retraction (N = 22 by controlled bleeding (1.5 ml/100 g. Gastric emptying of liquid was inhibited by 19-51.2% (P<0.05 after blood volume expansion (volumes of 1, 2, 3 or 5% body weight. Blood volume expansion produced a sustained increase in central venous pressure while mean arterial pressure was transiently increased during expansion (P<0.05. Blood volume retraction increased gastric emptying by 28.5-49.9% (P<0.05 and decreased central venous pressure and mean arterial pressure (P<0.05. Infusion of the shed blood 10 min after bleeding reversed the effect of retraction on gastric emptying. These findings suggest that gastric emptying of liquid is subject to modulation by the blood volume.

  4. Estimation of regional lung expansion via 3D image registration

    Science.gov (United States)

    Pan, Yan; Kumar, Dinesh; Hoffman, Eric A.; Christensen, Gary E.; McLennan, Geoffrey; Song, Joo Hyun; Ross, Alan; Simon, Brett A.; Reinhardt, Joseph M.

    2005-04-01

    A method is described to estimate regional lung expansion and related biomechanical parameters using multiple CT images of the lungs, acquired at different inflation levels. In this study, the lungs of two sheep were imaged utilizing a multi-detector row CT at different lung inflations in the prone and supine positions. Using the lung surfaces and the airway branch points for guidance, a 3D inverse consistent image registration procedure was used to match different lung volumes at each orientation. The registration was validated using a set of implanted metal markers. After registration, the Jacobian of the deformation field was computed to express regional expansion or contraction. The regional lung expansion at different pressures and different orientations are compared.

  5. Blood Volume: Importance and Adaptations to Exercise Training, Environmental Stresses and Trauma/Sickness

    Science.gov (United States)

    Sawka, Michael N.; Convertino, Victor A.; Eichner, E. Randy; Schnieder, Suzanne M.; Young, Andrew J.

    2000-01-01

    This paper reviews the influence of several perturbations (physical exercise, heat stress, terrestrial altitude, microgravity, and trauma/sickness) on adaptations of blood volume (BV), erythrocyte volume (EV), and plasma volume (PV). Exercise training can induced BV expansion; PV expansion usually occurs immediately, but EV expansion takes weeks. EV and PV expansion contribute to aerobic power improvements associated with exercise training. Repeated heat exposure induces PV expansion but does not alter EV. PV expansion does not improve thermoregulation, but EV expansion improves thermoregulation during exercise in the heat. Dehydration decreases PV (and increases plasma tonicity) which elevates heat strain and reduces exercise performance. High altitude exposure causes rapid (hours) plasma loss. During initial weeks at altitude, EV is unaffected, but a gradual expansion occurs with extended acclimatization. BV adjustments contribute, but are not key, to altitude acclimatization. Microgravity decreases PV and EV which contribute to orthostatic intolerance and decreased exercise capacity in astronauts. PV decreases may result from lower set points for total body water and central venous pressure, which EV decrease bay result form increased erythrocyte destruction. Trauma, renal disease, and chronic diseases cause anemia from hemorrhage and immune activation, which suppressions erythropoiesis. The re-establishment of EV is associated with healing, improved life quality, and exercise capabilities for these injured/sick persons.

  6. Süryaniler’in Tarihi ve Sosyolojik Yapısı

    OpenAIRE

    Ürek, Melki

    2014-01-01

    Bu makalede, Süryanilerin tarihi süreçleri ve sosyolojik yapıları ele alın-mıştır. Süryaniler yüzyıllar boyunca oldukça kaotik bir cooğrafyada yaşa-mışlarddır. Bu nedenle, dini, politik ve ideolojik açıdan pek çok farklı pa-radigmanın etkisi altında kalmışlardır. Bu olumsuz etki Süryanileri tarihi ve teolojik açıdan hatalı tanımlamalar ve yanlış isimlendirmeler gibi so-runlarla yüz yüze bırakmıştır. Ancak son zamanlarda üretilen akademik ve objektif çalışmalarla, Süryani liderlerin kendilerin...

  7. Soğukta ve Dondurulmuş Halde Muhafazaları Esnasında Meyve ve Sebzelerin Kalite ve Besleyici Değerlerinde Meydana Gelen Değişiklikler

    Directory of Open Access Journals (Sweden)

    Osman Cabı

    2015-02-01

    Full Text Available Kolay bozulabilir gıda maddelerinin daha uzun süre muhafaza edilmeleri amacıyla soğutma yönteminin kullanılmasının geçmişi tarih öncesi zamanlara kadar uzanmaktadır. Adı geçen “muhafaza” veya “korunma” sözcüğü, Weiser ve ark. 1971 tarafından, bir gıda maddesinin fiziksel, kimyasal kalitelerinin ve besleyici özelliklerinin belli bir süre müddetince veya mümkün olduğu kadar uzun bir periyot süresince saklanması şeklinde tanımlanmaktadır. Soğuğun çeşitli uygulamalarıyla muhafaza edilen gıda maddeleri gerek kantite gerekse çeşit ve yapı olarak geçtiğimiz son yıllarda büyük bir artış göstermişlerdir. İki yıl önceki değerlendirmelere göre, dünya kolay bozulabilir gıda maddeleri üretiminin 1 milyar ton olduğu Anquez, M. 1975 ve bu miktarın dörtte birinin (250 milyon ton herhangi bir şekilde işlenmesinde soğuğun kullanıldığı kabul edilmektedir.

  8. Negative thermal expansion in Sc2(WO4)3

    International Nuclear Information System (INIS)

    Evans, J.S.O.; Mary, T.A.; Sleight, A.W.

    1998-01-01

    Sc 2 (WO 4 ) 3 has been found to show the highly unusual property of negative thermal expansion over a temperature range of 10 to 1,073 K. Powder neutron diffraction data from 10 to 450 K shows an essentially linear decrease in cell volume as a function of temperature. The intrinsic linear coefficient of thermal expansion from this data is -2.2 x 10 -6 K -1 . The linear coefficient of thermal expansion measured on a ceramic bar of Sc 2 (WO 4 ) 3 can be as negative as -11 x 10 -6 K -1 due to microstructure changes as a function of temperature. Rietveld refinement as a function of temperature suggests that the intrinsic negative thermal expansion can be related to transverse vibrations of bridging oxygen atoms in the structure. The anharmonic nature of these vibrations leads to a coupled tilting of the quasi-rigid framework polyhedra. This tilting in turn causes the structure to become more dense with increasing temperature

  9. Osmanlı Seferlerinde Organizasyon Ve Lojistik The Organization And Logistics Of The Ottoman Flights

    Directory of Open Access Journals (Sweden)

    Uğur KURTARAN

    2012-12-01

    Full Text Available Understanding how the army, one of Ottoman Empire’s main dynamics and whose number reached over hundreds of thousands on occasions, was organized and how its needs were taken care of is not only important in better understanding the founding and the rising of the state but also important in better understanding the reasons for its downfall. Because just like other states founded throughout history, the political history and development of the Ottoman State has beenshaped in connection to its military operations. The success of themilitary operations is dependent on logistics activities, the preparationsand organizations before the military campaign. Indeed, when theOttoman State decided to go in to war, it has made importantpreparations in elevating the administrative and logistical organizationin the country to a more effective level. These preparations beforemilitary campaigns and strategies implemented called today as logisticshave led to the success of the military campaigns carried out in theOttoman State. At this point, the preparations implemented before thecampaigns play a big role in the growth of the state and expansion ofthe boundaries of the empire. So the key element that won or lost thewars for the Ottoman State throughout history was the far better prewarpreparations and organizations they applied much moresuccessfully than their contemporaries. Knowing how and in what waysthese preparations were implemented in the Ottoman State will broadenour perspective and help us better understand the underlying causes inOttoman victories. This study has been prepared in accordance withthese goals and objectives. In this study, it is intended to put forth howthe Ottomans did their preparations before and during the war and togive a different perspective to the current knowledge and experience inthe light of new resources. Osmanlı Devleti’nin temel dinamiklerinden birisi olan ve sayıları bazı dönemlerde yüz binleri geçen ordusunun

  10. BProVe: Tool support for business process verification

    DEFF Research Database (Denmark)

    Corradini, Flavio; Fornari, Fabrizio; Polini, Andrea

    2017-01-01

    This demo introduces BProVe, a tool supporting automated verification of Business Process models. BProVe analysis is based on a formal operational semantics defined for the BPMN 2.0 modelling language, and is provided as a freely accessible service that uses open standard formats as input data...

  11. Effects of Shrinkage Reducing Agent and Expansive Admixture on the Volume Deformation of Ultrahigh Performance Concrete

    OpenAIRE

    Anshuang, Su; Ling, Qin; Shoujie, Zhang; Jiayang, Zhang; Zhaoyu, Li

    2017-01-01

    This paper investigated the influences of shrinkage reducing agent and expansive admixture on autogenous and drying shrinkage of ultrahigh performance concrete (UHPC) containing antifoaming admixture. The shrinkage reducing agent was used at dosage of 0.5%, 1%, and 2% and the expansive admixture was used at dosage of 2% to 4% by mass of cementitious material. The results show that the air content of UHPC increases with the higher addition of shrinkage reducing agent and expansive admixtures. ...

  12. FEMİNİST ULUSLARARASI İLİŞKİLER VE ULUSLARARASI İLİŞKİLER ELEŞTİRİSİ: CİNSİYET, DEVLET VE GÜVENLİK

    OpenAIRE

    DOĞAN, Fazlı; ÖZLÜK, Duygu

    2016-01-01

    Bu çalışma bir sosyal ve politik teori olarak Feminizm’in Uluslararası İlişkilere (Uİ) girişi ve Feminist Uİ’nin ana akım Uİ teorilerine cinsiyet, devlet ve güvenlik başlıkları üzerinden yönelttiği eleştirileri değerlendirmektedir. Üç ana bölümden oluşan çalışmada öncelikle bir sosyal ve politik teori ve bir hareket olarak feminizmin tarihsel gelişimi kısaca tartışılmıştır. İkinci bölümde feminist hareketlerin uluslararası ilişkilerdeki gelişimi ve bir Uİ teorisi olarak Feminist Uİ’nin genel ...

  13. Distinct IL-7 signaling in recent thymic emigrants versus mature naïve T cells controls T-cell homeostasis.

    Science.gov (United States)

    Kim, Hye Kyung; Waickman, Adam T; Castro, Ehydel; Flomerfelt, Francis A; Hawk, Nga V; Kapoor, Veena; Telford, William G; Gress, Ronald E

    2016-07-01

    IL-7 is essential for T-cell survival but its availability is limited in vivo. Consequently, all peripheral T cells, including recent thymic emigrants (RTEs) are constantly competing for IL-7 to survive. RTEs are required to replenish TCR diversity and rejuvenate the peripheral T-cell pool. However, it remains unknown how RTEs successfully compete with resident mature T cells for IL-7. Moreover, RTEs express low levels of IL-7 receptors, presumably rendering them even less competitive. Here, we show that, surprisingly, RTEs are more responsive to IL-7 than mature naïve T cells as demonstrated by markedly increased STAT5 phosphorylation upon IL-7 stimulation. Nonetheless, adoptive transfer of RTE cells into lymphopenic host mice resulted in slower IL-7-induced homeostatic proliferation and diminished expansion compared to naïve donor T cells. Mechanistically, we found that IL-7 signaling in RTEs preferentially upregulated expression of Bcl-2, which is anti-apoptotic but also anti-proliferative. In contrast, naïve T cells showed diminished Bcl-2 induction but greater proliferative response to IL-7. Collectively, these data indicate that IL-7 responsiveness in RTE is designed to maximize survival at the expense of reduced proliferation, consistent with RTE serving as a subpopulation of T cells rich in diversity but not in frequency. Published 2016. This article is a U.S. Government work and is in the public domain in the USA.

  14. Feminist Sanatta Beden ve Yabancılaşma

    OpenAIRE

    Alp, Kafiye Özlem

    2015-01-01

    Feminizm, eril bir toplumda kadının, eşit hak ve özgürlüklere sahip olma gerekçelerine dayalı bir mücadele alanı olarak tanımlanabilir. Feminizmin, kamusal ve özel alanda kadın ayrımcılığına karşı başkaldırısı, insanın kendi emeğine ve kendi bedenine olan yabancılaşmasının bir sonucudur. Bu bakımdan feminizm, tüm tarihi boyunca toplumsal, felsefi, cinsel ve psikanalitik yabancılaşma kavramlarıyla yakın ilgi içinde olmuştur. Feminist sanat pratikleri; feminist kuramlar, toplumsal dinamikler...

  15. Effect of pressure on thermal expansion of UNiGa

    International Nuclear Information System (INIS)

    Honda, F.; Andreev, A.V.; Havela, L.; Prokes, K.; Sechovsky, V.

    1997-01-01

    The thermal expansion of single crystalline UNiGa has been measured along the crystallographic axes (a and c) under pressures up to 1.1 GPa. The linear thermal expansion both in the paramagnetic and antiferromagnetic ranges is strongly anisotropic. The antiferromagnetic ordering is accompanied by considerable (10 -4 ) linear spontaneous magnetostrictions (along the a- and c-axis) of different signs (-0.8 x 10 -4 and 1.8 x 10 -4 ). The mutual compensation of these two effects causes the volume effect to be rather small (∝10 -5 ). Two of the four magnetic phase transitions in UNiGa indicated by the expansion anomalies under ambient pressure are suppressed by pressures above 0.5 GPa. Results of our experiments allow to construct a pressure-temperature (p-T) magnetic phase diagram. (orig.)

  16. Yaşam Bilimleri ve Biyoteknoloji

    Directory of Open Access Journals (Sweden)

    Nalan YILMAZ SARIÖZLÜ

    2010-10-01

    Full Text Available Eskişehir/Türkiye’deki ılıca sularındaki bakteriyel topluluğun ortaya konulması ve incelenmesi için 7 ılıca su örneği 7 farklı ılıcadan toplanmıştır. Tüm örnekler dört farklı besi ortamına (nutrient agar, su-maya ekstraktı agar, triptik soy agar, nişasta-kazein agar inoküle edilmiştir. 50 °C’de 14 günlük inkübasyondan sonra tüm bakteri kolonilerinin sayımı yapılıp saflaştırılmıştır. Tüm izolatların gram reaksiyonları, katalaz veoksidazözellikleri belirlenmişve BIOLOG, VITEK veotomatikribotiplendirme sisteminde (RiboPrinter incelenmişlerdir. Bu bakterilerin ampisilin, gentamisin, trimetoprim-sülfametoksazol ve tetrasiklin antibiyotiklerine karşı dirençliliği incelenmiştir. Sonuç olarak normal insan florasına ilaveten ısıya dirençli patojenik mikroorganizmalar incelenen alandaki ılıca sularında (43-50 °C belirlenmiştir. Altı genusa ait 10 farklı tür Alysiella filiformis, Bordetella bronchiseptica, B. pertussis, Molexalla caprae, M. caviae, M. cuniculi, M. phenylpyruvica, Roseomonas fauriae, Delftia acidovorans ve Pseudomonas taetrolens olarak tanımlanmıştır

  17. Effects of Anti-VEGF on Predicted Antibody Biodistribution: Roles of Vascular Volume, Interstitial Volume, and Blood Flow

    Science.gov (United States)

    Boswell, C. Andrew; Ferl, Gregory Z.; Mundo, Eduardo E.; Bumbaca, Daniela; Schweiger, Michelle G.; Theil, Frank-Peter; Fielder, Paul J.; Khawli, Leslie A.

    2011-01-01

    Background The identification of clinically meaningful and predictive models of disposition kinetics for cancer therapeutics is an ongoing pursuit in drug development. In particular, the growing interest in preclinical evaluation of anti-angiogenic agents alone or in combination with other drugs requires a complete understanding of the associated physiological consequences. Methodology/Principal Findings Technescan™ PYP™, a clinically utilized radiopharmaceutical, was used to measure tissue vascular volumes in beige nude mice that were naïve or administered a single intravenous bolus dose of a murine anti-vascular endothelial growth factor (anti-VEGF) antibody (10 mg/kg) 24 h prior to assay. Anti-VEGF had no significant effect (p>0.05) on the fractional vascular volumes of any tissues studied; these findings were further supported by single photon emission computed tomographic imaging. In addition, apart from a borderline significant increase (p = 0.048) in mean hepatic blood flow, no significant anti-VEGF-induced differences were observed (p>0.05) in two additional physiological parameters, interstitial fluid volume and the organ blood flow rate, measured using indium-111-pentetate and rubidium-86 chloride, respectively. Areas under the concentration-time curves generated by a physiologically-based pharmacokinetic model changed substantially (>25%) in several tissues when model parameters describing compartmental volumes and blood flow rates were switched from literature to our experimentally derived values. However, negligible changes in predicted tissue exposure were observed when comparing simulations based on parameters measured in naïve versus anti-VEGF-administered mice. Conclusions/Significance These observations may foster an enhanced understanding of anti-VEGF effects in murine tissues and, in particular, may be useful in modeling antibody uptake alone or in combination with anti-VEGF. PMID:21436893

  18. Exact finite volume expectation values of local operators in excited states

    Energy Technology Data Exchange (ETDEWEB)

    Pozsgay, B. [MTA-BME “Momentum” Statistical Field Theory Research Group,Budafoki út 8, 1111 Budapest (Hungary); Szécsényi, I.M. [Department of Mathematical Sciences, Durham University, South Road, Durham, DH1 3LE (United Kingdom); Institute of Theoretical Physics, Eötvös Loránd University,Pázmány Péter sétány 1/A, 1117 Budapest (Hungary); Takács, G. [MTA-BME “Momentum” Statistical Field Theory Research Group,Budafoki út 8, 1111 Budapest (Hungary); Department of Theoretical Physics, Budapest University of Technology and Economics,Budafoki út 8, 1111 Budapest (Hungary)

    2015-04-07

    We present a conjecture for the exact expression of finite volume expectation values in excited states in integrable quantum field theories, which is an extension of an earlier conjecture to the case of general diagonal factorized scattering with bound states and a nontrivial bootstrap structure. The conjectured expression is a spectral expansion which uses the exact form factors and the excited state thermodynamic Bethe Ansatz as building blocks. The conjecture is proven for the case of the trace of the energy-moment tensor. Concerning its validity for more general operators, we provide numerical evidence using the truncated conformal space approach. It is found that the expansion fails to be well-defined for small values of the volume in cases when the singularity structure of the TBA equations undergoes a non-trivial rearrangement under some critical value of the volume. Despite these shortcomings, the conjectured expression is expected to be valid for all volumes for most of the excited states, and as an expansion above the critical volume for the rest.

  19. Exact finite volume expectation values of local operators in excited states

    International Nuclear Information System (INIS)

    Pozsgay, B.; Szécsényi, I.M.; Takács, G.

    2015-01-01

    We present a conjecture for the exact expression of finite volume expectation values in excited states in integrable quantum field theories, which is an extension of an earlier conjecture to the case of general diagonal factorized scattering with bound states and a nontrivial bootstrap structure. The conjectured expression is a spectral expansion which uses the exact form factors and the excited state thermodynamic Bethe Ansatz as building blocks. The conjecture is proven for the case of the trace of the energy-moment tensor. Concerning its validity for more general operators, we provide numerical evidence using the truncated conformal space approach. It is found that the expansion fails to be well-defined for small values of the volume in cases when the singularity structure of the TBA equations undergoes a non-trivial rearrangement under some critical value of the volume. Despite these shortcomings, the conjectured expression is expected to be valid for all volumes for most of the excited states, and as an expansion above the critical volume for the rest.

  20. High- and ultrahigh-field magnetic resonance imaging of naïve, injured and scarred vocal fold mucosae in rats

    Science.gov (United States)

    Kishimoto, Ayami Ohno; Kishimoto, Yo; Young, David L.; Zhang, Jinjin

    2016-01-01

    ABSTRACT Subepithelial changes to the vocal fold mucosa, such as fibrosis, are difficult to identify using visual assessment of the tissue surface. Moreover, without suspicion of neoplasm, mucosal biopsy is not a viable clinical option, as it carries its own risk of iatrogenic injury and scar formation. Given these challenges, we assessed the ability of high- (4.7 T) and ultrahigh-field (9.4 T) magnetic resonance imaging to resolve key vocal fold subepithelial tissue structures in the rat, an important and widely used preclinical model in vocal fold biology. We conducted serial in vivo and ex vivo imaging, evaluated an array of acquisition sequences and contrast agents, and successfully resolved key anatomic features of naïve, acutely injured, and chronically scarred vocal fold mucosae on the ex vivo scans. Naïve lamina propria was hyperintense on T1-weighted imaging with gadobenate dimeglumine contrast enhancement, whereas chronic scar was characterized by reduced lamina propria T1 signal intensity and mucosal volume. Acutely injured mucosa was hypointense on T2-weighted imaging; lesion volume steadily increased, peaked at 5 days post-injury, and then decreased – consistent with the physiology of acute, followed by subacute, hemorrhage and associated changes in the magnetic state of hemoglobin and its degradation products. Intravenous administration of superparamagnetic iron oxide conferred no T2 contrast enhancement during the acute injury period. These findings confirm that magnetic resonance imaging can resolve anatomic substructures within naïve vocal fold mucosa, qualitative and quantitative features of acute injury, and the presence of chronic scar. PMID:27638667

  1. High- and ultrahigh-field magnetic resonance imaging of naïve, injured and scarred vocal fold mucosae in rats.

    Science.gov (United States)

    Kishimoto, Ayami Ohno; Kishimoto, Yo; Young, David L; Zhang, Jinjin; Rowland, Ian J; Welham, Nathan V

    2016-11-01

    Subepithelial changes to the vocal fold mucosa, such as fibrosis, are difficult to identify using visual assessment of the tissue surface. Moreover, without suspicion of neoplasm, mucosal biopsy is not a viable clinical option, as it carries its own risk of iatrogenic injury and scar formation. Given these challenges, we assessed the ability of high- (4.7 T) and ultrahigh-field (9.4 T) magnetic resonance imaging to resolve key vocal fold subepithelial tissue structures in the rat, an important and widely used preclinical model in vocal fold biology. We conducted serial in vivo and ex vivo imaging, evaluated an array of acquisition sequences and contrast agents, and successfully resolved key anatomic features of naïve, acutely injured, and chronically scarred vocal fold mucosae on the ex vivo scans. Naïve lamina propria was hyperintense on T1-weighted imaging with gadobenate dimeglumine contrast enhancement, whereas chronic scar was characterized by reduced lamina propria T1 signal intensity and mucosal volume. Acutely injured mucosa was hypointense on T2-weighted imaging; lesion volume steadily increased, peaked at 5 days post-injury, and then decreased - consistent with the physiology of acute, followed by subacute, hemorrhage and associated changes in the magnetic state of hemoglobin and its degradation products. Intravenous administration of superparamagnetic iron oxide conferred no T2 contrast enhancement during the acute injury period. These findings confirm that magnetic resonance imaging can resolve anatomic substructures within naïve vocal fold mucosa, qualitative and quantitative features of acute injury, and the presence of chronic scar. © 2016. Published by The Company of Biologists Ltd.

  2. High- and ultrahigh-field magnetic resonance imaging of naïve, injured and scarred vocal fold mucosae in rats

    Directory of Open Access Journals (Sweden)

    Ayami Ohno Kishimoto

    2016-11-01

    Full Text Available Subepithelial changes to the vocal fold mucosa, such as fibrosis, are difficult to identify using visual assessment of the tissue surface. Moreover, without suspicion of neoplasm, mucosal biopsy is not a viable clinical option, as it carries its own risk of iatrogenic injury and scar formation. Given these challenges, we assessed the ability of high- (4.7 T and ultrahigh-field (9.4 T magnetic resonance imaging to resolve key vocal fold subepithelial tissue structures in the rat, an important and widely used preclinical model in vocal fold biology. We conducted serial in vivo and ex vivo imaging, evaluated an array of acquisition sequences and contrast agents, and successfully resolved key anatomic features of naïve, acutely injured, and chronically scarred vocal fold mucosae on the ex vivo scans. Naïve lamina propria was hyperintense on T1-weighted imaging with gadobenate dimeglumine contrast enhancement, whereas chronic scar was characterized by reduced lamina propria T1 signal intensity and mucosal volume. Acutely injured mucosa was hypointense on T2-weighted imaging; lesion volume steadily increased, peaked at 5 days post-injury, and then decreased – consistent with the physiology of acute, followed by subacute, hemorrhage and associated changes in the magnetic state of hemoglobin and its degradation products. Intravenous administration of superparamagnetic iron oxide conferred no T2 contrast enhancement during the acute injury period. These findings confirm that magnetic resonance imaging can resolve anatomic substructures within naïve vocal fold mucosa, qualitative and quantitative features of acute injury, and the presence of chronic scar.

  3. Türkiye’de Üretilen Kuru fasulyelerin Pişme Kalitesi ve Kompozisyonu (İngilizce

    Directory of Open Access Journals (Sweden)

    Recai Ercan

    2015-02-01

    Full Text Available Türkiye’de 2 bölgede yetiştirilen 8 kuru fasulye genotiplerinin fiziksel kriterleri ve pişme kalitesi ile mineral madde, tiyamin ve riboflavin miktarları saptanmıştır. Genotip ve yetiştirme lokasyonları ile bunların interaksiyonu bütün kriterleri önemli düzeyde etkilemiştir (P<0.05. Kuru ve yaş tohum ağırlığı, şişme kapasitesi ve indeksi, hidrasyon kapasitesi, kuru ve yaş hacim, kuru ve yaş pişme süresi ile Cu, Mn ve Na miktarları başlıca genotipden etkilenmiştir. Zn ve P miktarı ise çevreden etkilenmiştir. Kuru ve yaş tohum ağırlığı, kuru ve yaş hacim, hidrasyon ve şişme kapasitesi önemli düzeyde kuru ve yaş pişme süresi ile ilişkili olmuştur.

  4. Dynein-Based Accumulation of Membranes Regulates Nuclear Expansion in Xenopus laevis Egg Extracts.

    Science.gov (United States)

    Hara, Yuki; Merten, Christoph A

    2015-06-08

    Nuclear size changes dynamically during development and has long been observed to correlate with the space surrounding the nucleus, as well as with the volume of the cell. Here we combine an in vitro cell-free system of Xenopus laevis egg extract with microfluidic devices to systematically analyze the effect of spatial constraints. The speed of nuclear expansion depended on the available space surrounding the nucleus up to a threshold volume in the nanoliter range, herein referred to as the nuclear domain. Under spatial constraints smaller than this nuclear domain, the size of microtubule-occupied space surrounding the nucleus turned out to be limiting for the accumulation of membranes around the nucleus via the motor protein dynein, therefore determining the speed of nuclear expansion. This mechanism explains how spatial information surrounding the nucleus, such as the positioning of the nucleus inside the cell, can control nuclear expansion. Copyright © 2015 Elsevier Inc. All rights reserved.

  5. Thermal expansion of two-dimensional itinerant nearly ferromagnetic metal

    International Nuclear Information System (INIS)

    Konno, R; Hatayama, N; Takahashi, Y; Nakano, H

    2009-01-01

    Thermal expansion of two-dimensional itinerant nearly ferromagnetic metal is investigated according to the recent theoretical development of magneto-volume effect for the three-dimensional weak ferromagnets. We particularly focus on the T 2 -linear thermal expansion of magnetic origin at low temperatures, so far disregarded by conventional theories. As the effect of thermal spin fluctuations we have found that the T-linear thermal expansion coefficient shows strong enhancement by assuming the double Lorentzian form of the non-interacting dynamical susceptibility justified in the small wave-number and low frequency region. It grows faster in proportional to y -1/2 as we approach the magnetic instability point than two-dimensional nearly antiferromagnetic metals with ln(1/y s ) dependence, where y and y s are the inverses of the reduced uniform and staggered magnetic susceptibilities, respectively. Our result is consistent with the Grueneisen's relation between the thermal expansion coefficient and the specific heat at low temperatures. In 2-dimensional electron gas we find that the thermal expansion coefficient is divergent with a finite y when the higher order term of non-interacting dynamical susceptibility is taken into account.

  6. Analyzing Program Termination and Complexity Automatically with AProVE

    DEFF Research Database (Denmark)

    Giesl, Jürgen; Aschermann, Cornelius; Brockschmidt, Marc

    2017-01-01

    In this system description, we present the tool AProVE for automatic termination and complexity proofs of Java, C, Haskell, Prolog, and rewrite systems. In addition to classical term rewrite systems (TRSs), AProVE also supports rewrite systems containing built-in integers (int-TRSs). To analyze...... programs in high-level languages, AProVE automatically converts them to (int-)TRSs. Then, a wide range of techniques is employed to prove termination and to infer complexity bounds for the resulting rewrite systems. The generated proofs can be exported to check their correctness using automatic certifiers...

  7. İRAN VE REJİM İSTİKRARI

    Directory of Open Access Journals (Sweden)

    Özgür ÜŞENMEZ

    2015-07-01

    Full Text Available ÖZ: Bu çalışma, İran rejiminin son yıllarda Orta Doğu'yu sarsan isyanlar ve istikrarsızlıklara-Batı'daki beklentilerin aksine- geçmişten, özellikle 1979'daki devrimden miras kalan sosyal yapı ve politikaların etkisiyle direnebildiğini iddia ediyor. Tunus ve Mısır'daki halk isyanları, temel aktör olan alt sınıflar ve onların neo-liberal ekonomik politikalara muhalefetiyle yayılırken, İran’da devrim sonrası gelişen sosyal devlet mekanizması hala halk ile rejimin tamamen birbirine yabancılaşmasını önlemekte. Ancak son yıllarda ortaya çıkan yeni gerilimler ve İran'ın uyguladığı ekonomi politikaları rejimin krizini derinleştirebilir. Bu nedenledir ki Orta Doğu'yu ve özelde İran'ı anlamak için hegemonik blokların tarihsel değişimini inceleyen ucu açık bir analiz elzemdir. ABSTRACT: This article argues that contrary to the expectations of the Western World, Iranian regime successfully resisted the revolutionary tides of the Arab Spring. Most important determinant of this process for Iran was the legacy of the 1979 revolution and it's associated structures that relatively protects the most vulnerable parts of the population against the wide spread neo-liberal economic policies in the Middle East. So with that feature Iran differs from the Tunisian and the Egyptian examples. In order to understand these features further this essay adapts a historical analysis of changes in hegemonic blocs in Iran since 1979.

  8. Hamburgerlerin bazı Fiziksel, Kimyasal ve Mikrobiyolojik Özelliklerine Donmuş Depolama Sıcaklığı ve Depolama Süresinin Etkisi Üzerinde Araştırma

    Directory of Open Access Journals (Sweden)

    A. Hamdi Ertaş

    2015-02-01

    Full Text Available Ticari amaçla üretilen hamburgerler, -8 oC ve –26 oC’de 85 gün süre ile depolanmışlar ve depolama sıcaklığının ve süresinin hamburgerlerin bazı fiziksel, kimyasal ve mikrobiyolojik özellikleri üzerine olan etkileri araştırılmıştır. Fiziksel kriterler olarak su tutma kapasitesi (STK, pişirme kaybı (PK ve büzülme derecesi (BD; kimyasal kriterler olarak rutubet, protein, yağ miktarları ile pH değeri ve tiyobarbütirik asit (TBA sayısı; mikrobiyolojik kriterler olarak ise toplam mezofil aerob bakteri (TMAB sayısı, psikrofil bakteri (PB sayısı ve koliform grubu bakteri (KGB sayısı dikkate alınmıştır. Depolama sıcaklığı ve depolama süresinin rutubet, protein, yağ miktarları, STK, PK ve BD üzerine etkisinin olmadığı, pH değeri üzerine p<0.01 düzeyinde etkisinin olduğu, TBA-sayısı üzerine depolama sıcaklığının p<0.01 düzeyinde depolama süresinin p<0.05 düzeyinde etkisi olduğu belirlenmiştir. –8 oC de depolama, hamburgerlerin pH değerlerini ve TBA-sayılarını önemli düzeyde artırırken, -26 oC de depolamada artış daha az düzeyde olmuştur. TMAB, PB ve KGB sayılarına, depolama sıcaklığının ve depolama süresinin etkisi görülmüş (p<0.01; -8 oC’de, depolama süresine bağlı olarak TMAB, PB ve KGB sayılarında sürekli bir artış görülürken –26 oC’de depolamada azalma olmuştur.

  9. Thermal expansion of CeCu5.8Ag0.2

    International Nuclear Information System (INIS)

    Kuechler, R.; Gegenwart, P.; Heuser, K.; Scheidt, E.-W.; Stewart, G.R.; Steglich, F.

    2005-01-01

    We present low-temperature thermal expansion measurements on the heavy fermion system CeCu 5.8 Ag 0.2 , which is located at an antiferromagnetic (AF) quantum critical point (QCP). At zero magnetic field, the volume expansion coefficient divided by temperature shows a logarithmic divergence upon cooling below 1K. This temperature dependence is incompatible with the predictions of the itinerant spin-density wave theory for an AF QCP. The application of magnetic fields leads to a cross-over to Landau Fermi liquid behavior as expected for a zero-field QCP

  10. Halit Fahri Ozansoy'un Gülistanlar ve Harabeler Adlı Eserinde Bahçe İmajları ve Renkler Garden Images and Colors in Halit Fahri Ozansoy’s Work of Gülistanlar ve Harabeler

    Directory of Open Access Journals (Sweden)

    Hüseyin DOĞRAMACIOĞLU

    2012-12-01

    Full Text Available Halit Fahri Ozansoy’s poetry books of Gülistanlar ve Harabeler printed with old letters but not transformed to the Latin alphabet until now. In his work, garden images and colors which loaded special meaning of poet was known as hidden pearls and no research have been made on this work till now. Garden images in poetry are sometimes colorful, light and sometimes dull and dark. These images change with the with the poet's spirit world. We can visualize the garden images like an oil painting. These images drawn by the poet's words, show poet’s mood like a mirror. The colors used in the poem vary with garden images. This change appears with the change of the mental status of the poet. Thus, the poet uses the colors in accordancewith the different tables and his mood. When there are a lively andwarm colors in optimistic tables, dark and dull colors chosen inpessimistic tables. The poet's choice of the colors is not a coincidence.This selectivity included to poetry with different sensations. In his work,Ozansoy has described variety of colors in different gardens.Imagination, imagery and various emotions had been made with oneaccord in his depictions. The colors and portraits of garden form thepoet’s imagination. Colorful memories in the garden which experiencedin a darling moves from poet's imagination to the verses of the poem.Imagination, colors and gardens are described with darling. Theseimageries compose the garden images and semantic change of thecolors. Halit Fahri Ozansoy’un Gülistanlar ve Harabeler adlı şiir kitabı eski harflerle basılmış ancak günümüze kadar Latin harflerine aktarılmamıştır. Bu eserde şairin bahçe imajları ve renklere yüklediği anlamlar saklı inciler gibi gizli kalmış ve günümüze kadar üzerinde inceleme yapılmamıştır. Şiirdeki bahçe imajları bazen renkli, ışıklı ve bazen de donuk ve karanlıktır. Şairin değişen ruh dünyası ile birlikte bu imajlar da değişir. Bah

  11. Beneficial Use of Scrap Tire Rubber in Low-volume Road and Bridge Construction with Expansive Soils

    Science.gov (United States)

    2010-07-14

    Billions of dollars in damages are attributed to expansive soils in the United States (Jones and Jones 1987) and in many other countries each year. Geotechnical design and analyses in/on/with expansive soils may involve additional complications that ...

  12. Anisotropic Margin Expansions in 6 Anatomic Directions for Oropharyngeal Image Guided Radiation Therapy

    International Nuclear Information System (INIS)

    Yock, Adam D.; Garden, Adam S.; Court, Laurence E.; Beadle, Beth M.; Zhang, Lifei; Dong, Lei

    2013-01-01

    Purpose: The purpose of this work was to determine the expansions in 6 anatomic directions that produced optimal margins considering nonrigid setup errors and tissue deformation for patients receiving image-guided radiation therapy (IGRT) of the oropharynx. Methods and Materials: For 20 patients who had received IGRT to the head and neck, we deformably registered each patient's daily images acquired with a computed tomography (CT)-on-rails system to his or her planning CT. By use of the resulting vector fields, the positions of volume elements within the clinical target volume (CTV) (target voxels) or within a 1-cm shell surrounding the CTV (normal tissue voxels) on the planning CT were identified on each daily CT. We generated a total of 15,625 margins by dilating the CTV by 1, 2, 3, 4, or 5 mm in the posterior, anterior, lateral, medial, inferior, and superior directions. The optimal margins were those that minimized the relative volume of normal tissue voxels positioned within the margin while satisfying 1 of 4 geometric target coverage criteria and 1 of 3 population criteria. Results: Each pair of geometric target coverage and population criteria resulted in a unique, anisotropic, optimal margin. The optimal margin expansions ranged in magnitude from 1 to 5 mm depending on the anatomic direction of the expansion and on the geometric target coverage and population criteria. Typically, the expansions were largest in the medial direction, were smallest in the lateral direction, and increased with the demand of the criteria. The anisotropic margin resulting from the optimal set of expansions always included less normal tissue than did any isotropic margin that satisfied the same pair of criteria. Conclusions: We demonstrated the potential of anisotropic margins to reduce normal tissue exposure without compromising target coverage in IGRT to the head and neck

  13. Series expansions of the density of states in SU(2) lattice gauge theory

    International Nuclear Information System (INIS)

    Denbleyker, A.; Du, Daping; Liu, Yuzhi; Meurice, Y.; Velytsky, A.

    2008-01-01

    We calculate numerically the density of states n(S) for SU(2) lattice gauge theory on L 4 lattices [S is the Wilson's action and n(S) measures the relative number of ways S can be obtained]. Small volume dependences are resolved for small values of S. We compare ln(n(S)) with weak and strong coupling expansions. Intermediate order expansions show a good overlap for values of S corresponding to the crossover. We relate the convergence of these expansions to those of the average plaquette. We show that, when known logarithmic singularities are subtracted from ln(n(S)), expansions in Legendre polynomials appear to converge and could be suitable to determine the Fisher's zeros of the partition function.

  14. The extended (G/G)-expansion method and travelling wave ...

    Indian Academy of Sciences (India)

    Home; Journals; Pramana – Journal of Physics; Volume 82; Issue 6. The extended (′/)-expansion method and travelling wave solutions for the perturbed nonlinear Schrödinger's equation with Kerr law nonlinearity. Zaiyun Zhang Jianhua Huang Juan Zhong Sha-Sha Dou Jiao Liu Dan Peng Ting Gao. Research Articles ...

  15. Leptodermous expansion of finite-nucleus incompressibility

    International Nuclear Information System (INIS)

    Nayak, R.C.

    1990-01-01

    We consider the influence of higher-order terms in the leptodermous expansion used to extract the incompressibility K v of infinite nuclear matter from data on the breathing mode of finite nuclei. The terms we calculate are the curvature term K cv A -2/3 , the surface-symmetry term K ss I 2 A -1/3 , the quartic volume-symmetry term K 4 I 4 , and a Coulomb-exchange term. Working within the framework of the scaling model we derive expressions for their coefficients in terms of quantities that are defined for infinite and semi-infinite nuclear matter. We calculate these coefficients for four different Skyrme-type forces, using the extended Thomas-Fermi (ETF) approximation. With the same forces we also calculate the incompressibility K (A, I) for a number of finite nuclei, fit the results to the leptodermous expansion, and thereby extract new results for the same coefficients. The comparison of the two calculations shows that the leptodermous expansion is converging rapidly. Of the new terms, the term K 4 I 4 is quite negligible, the curvature term should be included, and we discuss to what extent the other higher-order terms are significant. (orig.)

  16. Pre-emptif uygulanan intravenöz, spinal ve epidural morfinin erken postoperatif analjezi ve stres yanıt üzerine etkileri

    OpenAIRE

    Düger, Cevdet; Ayvaz, Hakan; Bulut, Filiz; Gürsoy, Sinan; Kaygusuz, Kenan; İsbir, Ahmet Cemil; Özdemir Kol, İclal; Gürelik, Bilge; Mimaroğlu, Caner

    2013-01-01

    Özet Bu çalışmada, preemptif uygulanan iv, spinal ve epidural morfinin erken postoperatif dönemdeki analjezik tüketimi ve stres yanıt üzerine etkilerini belirlemek amaçlandı. Alt batın operasyonu uygulanacak ASA I-II grubuna giren 60 hasta rasgele üç gruba ayrıldı. Grup I’e indüksiyondan 5 dk. önce 5 mg iv morfin, Grup II’ye indüksiyondan 5 dk önce 0,5 mg intratekal morfin, Grup III’e indüksiyondan 30dk önce 5mg epidural morfin uygulandı. Anestezi indüksiyonu 0,1 µg kg-1 fentanil ve 4-7 mg k...

  17. Volume Stability of Bitumen Bound Building Blocks

    Directory of Open Access Journals (Sweden)

    Thanaya I.N.A.

    2010-01-01

    Full Text Available This paper covers results of laboratory investigations on the volume stability of masonry units incorporating waste materials bound with bitumen (Bitublocks, due to moisture adsorption, thermal exposure and vacuum saturation. The materials used were steel slag, crushed glass, coal fly ash, and 50 pen bitumen. The samples were produced in hot mix method, compacted, then exposed to moist and temperature. It was found that moisture adsorption from the environment caused the Bitublock to expand. The samples with less intense curing regime experienced lower expansion and became stable faster, and vice versa. Under thermal condition (at 70°C, the samples with less intense curing regime underwent higher expansion, and vice versa. They were also highly reversible. Their volume stability was found unique under water exposure. The expansion on first vacuum saturation cycle was irreversible, then largely reversible on the following cycles.

  18. Türkiye ve Dünyada Ayva Piyasası

    Directory of Open Access Journals (Sweden)

    Bekir Sıtkı Şirikçi

    2017-07-01

    Full Text Available Bu çalışmada dünyada ve Türkiye’de ayva piyasası irdelenmiştir. Çalışmada birincil verileri, ayva üretiminin yoğun olarak yapıldığı Sakarya, Antalya, Bursa, Bilecik ve Denizli illerinde farklı pazarlama seviyelerindeki 28 aracı işletme ile anket yöntemi ile elde edilen veriler oluşturmuştur. İkincil veriler ise FAO ve TÜİK gibi kurumlarının verilerinden hareketle elde edilmiştir. Dönem başlangıcı olan 1981-1985 ortalamasına göre 324465 ton olan dünya ayva üretimi %94,3 artışla 2013 yılında 630325 tona yükselmiştir. Dünya ayva üretiminde önemli ülkeler; Türkiye, Çin, Özbekistan, Fas ve İran’dır. Türkiye’de ayva üretimi, 1981-1985 ortalamasına göre 1.60 kat artmıştır. Ayva üretimindeki bu artışta ağaç başına verimdeki yükselmenin katkısı önemlidir (%40 verimde artış. Dünyada üretilen ayvanın %5,3’ü ihracata konu olmaktadır. Dünya ayva ihracat miktarı 8,32 kat, değeri ise 38,42 kat artmıştır. Ayva ihracat değerlerinde en yüksek paya Hollanda sahiptir (%33,6’sı. Hollanda’yı sırasıyla Türkiye, Avusturya ve İran takip etmektedir. Türkiye’nin dünya ihracat değerindeki payı ise %31,1’dir. Dünya ayva ithalatında %23,3 pay ile Rusya birinci sıradadır. Rusya’yı sırası ile Avusturya ve Almanya takip etmektedir. Türkiye’nin ayva üretiminin %9,4’ü ihracata konu olmaktadır. Önemli ayva üreticisi iller; Sakarya, Bursa, Antalya, Bilecik ve Denizli’dir. Görüşülen aracıların 15’i ayvada pazarlama aşamasında karşılaştıkları en önemli sorunun istenilen zaman, miktar, kalite ve fiyatta ayva bulunmamasını (%54 belirtmiştir.

  19. The effect of atypical antipsychotics on pituitary gland volume in patients with first-episode psychosis: a longitudinal MRI study.

    Science.gov (United States)

    Nicolo, John-Paul; Berger, Gregor E; Garner, Belinda A; Velakoulis, Dennis; Markulev, Connie; Kerr, Melissa; McGorry, Patrick D; Proffitt, Tina-Marie; McConchie, Mirabel; Pantelis, Christos; Wood, Stephen J

    2010-01-01

    Pituitary volume is currently measured as a marker of hypothalamic-pituitary-adrenal hyperactivity in patients with psychosis despite suggestions of susceptibility to antipsychotics. Qualifying and quantifying the effect of atypical antipsychotics on the volume of the pituitary gland will determine whether this measure is valid as a future estimate of HPA-axis activation in psychotic populations. To determine the qualitative and quantitative effect of atypical antipsychotic medications on pituitary gland volume in a first-episode psychosis population. Pituitary volume was measured from T1-weighted magnetic resonance images in a group of 43 first-episode psychosis patients, the majority of whom were neuroleptic-naïve, at baseline and after 3months of treatment, to determine whether change in pituitary volume was correlated with cumulative dose of atypical antipsychotic medication. There was no significant baseline difference in pituitary volume between subjects and controls, or between neuroleptic-naïve and neuroleptic-treated subjects. Over the follow-up period there was a negative correlation between percentage change in pituitary volume and cumulative 3-month dose of atypical antipsychotic (r=-0.37), i.e. volume increases were associated with lower doses and volume decreases with higher doses. Atypical antipsychotic medications may reduce pituitary gland volume in a dose-dependent manner suggesting that atypical antipsychotic medication may support affected individuals to cope with stress associated with emerging psychotic disorders.

  20. Berkeley 51 Kümesinin Temel ve Astrofiziksel Parametrelerinin Belirlenmesi

    Directory of Open Access Journals (Sweden)

    İnci Akkaya Oralhan

    2016-10-01

    Full Text Available Galaksimizin birinci çeyreğinde bulunan ve daha önce çok az çalışılmış açık yıldız kümelerinden biri olan Berkeley 51 kümesinin temel astrofiziksel ve yapısal parametreleri CCD UBV(RIC ve 2MASS JHKS verileri kullanılarak elde edilmiştir. Kümeye ait CCD UBV(RIC verileri Meksika’da bulunan San Pedro Martir Ulusal Gözlemevi’nden 84cm’lik teleskop ile alınmıştır. Küme üyeliklerinin belirlenmesinde ise PPMXL kataloğundaki öz hareket verileri kullanılmıştır. Buna küre bu küme için elde edilen limit yarıçap Rlim=2.5 yay dakikası, kızarma E(B-V=0.85±0.05 kadir, E(J-H=0.28±0.02 kadir, uzaklık modülü DM=(m-M0=10.66±0.04 pc, uzaklığı d=1355±27 pc ve logaritmik yaş log(A=9.54±0.03 Myıl olarak bulunmuştur. Küme için ilk kez bulunan metal ve ağır element bolluğu ise sırasıyla [Fe/H]=-0.38 ve Z=0.006 olarak elde edilmiştir.Anahtar kelimeler: Açık yıldız kümeleri-Berkeley 51

  1. S-24: Hamstring Tendon Otogrefti ile Ön Çapraz Bağ Rekonstrüksiyonu Sonrasında Modifiye ve Hızlandırılmış Fizyoterapi ve Rehabilitasyon Programının Propriosepsiyon Denge ve Koordinasyon Üzerine Etkileri

    Directory of Open Access Journals (Sweden)

    İbrahim Babayiğit

    2017-03-01

    Full Text Available Bu çalışmanın amacı; izole ön çapraz bağ (ÖÇB veya ön çapraz bağ ile birlikte menisküs yaralanması geçiren kişilerin, hamstring tendon otogrefti ile ön çapraz bağ rekonstrüksiyonu sonrasında modifiye ve hızlandırılmış fizyoterapi ve rehabilitasyon programının propriosepsiyon, dinamik denge üzerine etkilerini araştırmaktır. Çalışma artroskopik Hamstring Tendon Otogrefti ile Ön Çapraz Bağ Rekonstrüksiyonu Cerrahisi Geçiren 20 kişi (n=20 K/E: 2/18 ile gerçekleştirilmiştir. Tüm olguların operasyon öncesinde (preop diz propriosepsiyon değerleri gözler açık ve kapalı olarak 15, 30, 45 ve 60 derecede Dijital Gonyometre ile ölçüldü. Operasyon sonrası (postop tüm olgular modifiye, hızlandırılmış fizyoterapi ve rehabilitasyon programına alındı. Operasyon sonrası 3., 6., 12. hafta ve 6. Ay’da propriosepsiyon ölçümleri tekrar edildi.Dinamik denge ölçümleri 3., 6., 12. hafta ve 6. Ay’da horizontal, sağ oblik, sol oblik ve tek ayak denge ölçümleri olarak yapıldı. Fonksiyonel seviyelerini değerlendirmek için Lysholm skoru ve ağrıyı değerlendirmek için VAS (Visual Ağrı Skoru, olguların fonksiyonel performansları durumlarını değerlendirmek için tek ayak atlama, çift ayak atlama ve çapraz atlama testleri uygulandı. Çalışmamızda olguların gözler açık ve kapalı durumda propriosepsiyon (15°, 30°, 45° ve 60° ölçüm sonuçları postoperatif dönemde preoperatif döneme göre 12. Hafta ve 6. Ayda istatistiksel olarak anlamlı düzeyde düzelme göstermiştir (p<0.05. Olgularda 3. haftadan sonra dinamik denge testlerinde önemli gelişme saptanmışır, bu artış istatistiksel olarak da anlamlıdır (p<0.05. 6 Ayda yapılan fonksiyonel performans testlerini etkileyen bağımsız değişkenler çoklu regresyon analizinde araştırılmış, 60° ölçülen propriosepsiyon sonuçları ve sol tarafın tek adım atlama test skoru, sağ tarafta tek ad

  2. The Nature of VeLLOs

    Science.gov (United States)

    Huard, Tracy L.; Pound, Marc W.; Mundy, Lee; Dunham, Michael

    2018-01-01

    Very Low Luminosity Objects (VeLLOs) are young stellar sources that are defined by luminosities less than 0.1 solar luminosity and rising mid-infrared spectral energy distributions. But, what exactly are they? Brown dwarfs or low-mass stars in formation? Systems exhibiting low accretion rates? Extremely young objects? We have completed an ALMA survey of 33 candidates in the nearby Serpens, Ophiuchus, and Lupus star-forming molecular clouds. Continuum emission at 1.3 mm, consistent with the presence of an inner envelope and/or disk, was detected toward 17 candidates, with at least 6 of these candidates exhibiting CO outflow emission, suggesting ongoing formation. We will present these observations and results, and discuss their implications concerning the nature of VeLLOs.

  3. Radurizasyonun Tavuk Etlerinin Duyusal, Kimyasal ve Mikrobiyolojik Kalitesi Üzerine Etkisi

    Directory of Open Access Journals (Sweden)

    Nuray Kolsarıcı

    2015-02-01

    Full Text Available Araştırmada 1, 2 ve 3 kGy dozunda uygulanan iyonize radyasyonun (Radurizasyon tavuk but ve göğüs etlerinin mikrobiyolojik, kimyasal ve duyusal kalitelerine olan etkisi üzerinde çalışılmıştır. 6-8 haftalık broilerler kesilerek but ve göğüs etlerine parçalandıktan sonra biri açık kontrol olmak üzere 5 gruba ayrılmış ve 4 grup vakum paketlenmiştir. Vakum paketi gruplardan biri vakumlu kontrol olarak ayrılırken, diğer gruplar 1, 2 ve 3 kGy olmak üzere iyonize radyasyona tabi tutulmuştur. 0. günden başlamak üzere 3’er günlük periyotlarla gruplar analize alınmış, toplam mezofilik aerob, toplam psikrofilik aerob, stafilokok ve laktik asit bakterileri ile pH ve TBA değeri belirlenmiştir. Ayrıca örneklerin duyusal özellikleri de panel oluşturularak saptanmıştır. Elde edilen tüm veriler varyans analizi ile değerlendirilmiştir. Araştırma bulgularına göre tavuk but ve göğüs etlerinde radurizasyon sonrası bakteriyel yükte azalma gözlenmiştir. Radurizasyonun toplam mezofilik aerobik ve toplam psikrofilik aerobik bakteriler üzerine olan etkisi stafilokok ve laktik asit bakterilerine kıyasla daha yüksek düzeyde olup, özellikle laktik asit bakterilerinde zayıf kalmıştır. PH ve TBA değerleri açısından radurizasyonun değişiklik yaratmadığı gözlenmiştir. Bununla birlikte 3 kGy ışınlanmış örneklerin raf ömrü 27 gün civarında olurken 2 kGy ışınlı örnekler 24 günde, 1 kGy ışınlı örnekler 18 günde, vakumlu kontroller 15 günde, açık kontroller 9 gün civarında tüketim özelliğini yitirmiştir. Duyusal değerlendirmelerde alınan sonuçlarda ışınlanmış örneklerin renk, görünüş, aroma, gevreklik gibi özellikleri kontrollere göre farklı olmayıp, tüm gruplar pazarlanabilir nitelikte bulunmuşlardır.

  4. Characterization of Mixtures. Part 2: QSPR Models for Prediction of Excess Molar Volume and Liquid Density Using Neural Networks.

    Science.gov (United States)

    Ajmani, Subhash; Rogers, Stephen C; Barley, Mark H; Burgess, Andrew N; Livingstone, David J

    2010-09-17

    In our earlier work, we have demonstrated that it is possible to characterize binary mixtures using single component descriptors by applying various mixing rules. We also showed that these methods were successful in building predictive QSPR models to study various mixture properties of interest. Here in, we developed a QSPR model of an excess thermodynamic property of binary mixtures i.e. excess molar volume (V(E) ). In the present study, we use a set of mixture descriptors which we earlier designed to specifically account for intermolecular interactions between the components of a mixture and applied successfully to the prediction of infinite-dilution activity coefficients using neural networks (part 1 of this series). We obtain a significant QSPR model for the prediction of excess molar volume (V(E) ) using consensus neural networks and five mixture descriptors. We find that hydrogen bond and thermodynamic descriptors are the most important in determining excess molar volume (V(E) ), which is in line with the theory of intermolecular forces governing excess mixture properties. The results also suggest that the mixture descriptors utilized herein may be sufficient to model a wide variety of properties of binary and possibly even more complex mixtures. Copyright © 2010 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  5. Volumetric changes of the nose and nasal airway 2 years after tooth-borne and bone-borne surgically assisted rapid maxillary expansion

    NARCIS (Netherlands)

    Nada, R.M.; Loon, B. van; Schols, J.G.J.H.; Maal, T.J.J.; Koning, M.J.J. de; Mostafa, Y.A.; Kuijpers-Jagtman, A.M.

    2013-01-01

    This study aimed to assess the effects of bone-borne and tooth-borne surgically assisted rapid maxillary expansion on the volumes of the nose and nasal airway 2 yr after maxillary expansion. This prospective cohort study included 32 patients with transverse maxillary hypoplasia. Expansion was

  6. Most B cells in non-lymphoid tissues are naïve.

    Science.gov (United States)

    Inman, Charlotte F; Murray, Tamsin Zangerle; Bailey, Mick; Cose, Stephen

    2012-02-01

    The current view of lymphocyte migration states that naïve lymphocytes re-circulate between the blood and the lymph via the lymph nodes, but are not able to access non-lymphoid tissues. We examined B lymphocytes in peripheral tissues and found that the majority were phenotypically similar to naïve B cells in lymphoid tissues and were located within the parenchyma, not associated with blood vessels. The mutation rate within the Vh region of these cells was substantially less than the rate attributed to somatic hypermutation and was identical to that observed in naïve B cells isolated from the lymph nodes, showing the presence of naïve B cells in the non-lymphoid organs. Further, using FTY720-treated mice, we showed that naïve B cells migrate through the peripheral tissues and, using pertussis toxin, that the entry of B cells was not controlled by chemokine-mediated signalling events. Overall, these results show that naïve B lymphocytes constitute the majority of the total B-cell population in non-lymphoid tissues and suggest that these cells may re-circulate through the periphery as part of their normal migration pathway. This has implications for the current view of the role of naïve B cells in priming and tolerance.

  7. Effects of fibers on expansive shotcrete mixtures consisting of calcium sulfoaluminate cement, ordinary Portland cement, and calcium sulfate

    Directory of Open Access Journals (Sweden)

    H. Yu

    2018-04-01

    Full Text Available The mining industry often uses shotcrete for ground stabilization. However, cracking within shotcrete is commonly observed, which delays production schedules and increases maintenance costs. A possible crack reduction method is using expansive shotcrete mixture consisting of calcium sulfoaluminate cement (CSA, ordinary Portland cement (OPC, and calcium sulfate (CS to reduce shrinkage. Furthermore, fibers can be added to the mixture to restrain expansion and impede cracking. The objective of this paper is to study the effects of nylon fiber, glass fiber, and steel fiber on an expansive shotcrete mixture that can better resist cracking. In this study, parameters such as density, water absorption, volume of permeable voids, unconfined compressive strength (UCS, splitting tensile strength (STS, and volume change of fiber-added expansive mixtures were determined at different time periods (i.e. the strengths on the 28th day, and the volume changes on the 1st, 7th, 14th, 21st, and 28th days. The results show that addition of fibers can improve mixture durability, in the form of decreased water absorption and reduced permeable pore space content. Moreover, the expansion of the CSA-OPC-CS mixture was restrained up to 50% by glass fiber, up to 43% by nylon fiber, and up to 28% by steel fiber. The results show that the STS was improved by 57% with glass fiber addition, 43% with steel fiber addition, and 38% with nylon fiber addition. The UCS was also increased by 31% after steel fiber addition, 26% after nylon fiber addition, and 16% after glass fiber addition. These results suggest that fiber additions to the expansive shotcrete mixtures can improve durability and strengths while controlling expansion. Keywords: Shotcrete, Restrained expansion, Fibers, Calcium sulfoaluminate cement (CSA, Ordinary Portland cement (OPC, Calcium sulfate (CS

  8. Excess free volume in metallic glasses measured by X-ray diffraction

    International Nuclear Information System (INIS)

    Yavari, Alain Reza; Moulec, Alain Le; Inoue, Akihisa; Nishiyama, Nobuyuki; Lupu, Nicoleta; Matsubara, Eiichiro; Botta, Walter Jose; Vaughan, Gavin; Di Michiel, Marco; Kvick, Ake

    2005-01-01

    In crystalline materials, lattice expansion as measured by diffraction methods differs from the expansion of the sample dimensions as measured by dilatometry, due to the contribution of thermal vacancies to the latter. We have found that in glassy materials and metallic glasses in particular, this is not the case for the contribution of free volume. These findings are the first direct experimental confirmation of simulation results indicating that atomic size holes are unstable in glasses such that free volume is dispersed randomly. This allows direct measurement of excess free volume in glasses using diffraction methods in place of dilatometry, which is difficult to use once the sample softens at the glass transition temperature T g and above. Quenched-in and deformation-induced free-volume ΔV f were measured by X-ray diffraction in transmission during heating using synchrotron light. The measured thermal expansion coefficients α th were the same as in dilatometry. The glass transition T g appeared as a break in the value of α th at T g . The 'change-of-slope method' was applied to the kinetics of relaxation to derive the activation energy for the free-volume annihilation process

  9. Kazein, Kazeinat ve Soya Proteini ile Hazırlanan Taklit Taze Kaşar Peynirlerinin Fizikokimyasal ve Tekstürel Özellikleri (İngilizce

    Directory of Open Access Journals (Sweden)

    Pınar Balkır

    2015-02-01

    Full Text Available Bu çalışmada, dört farklı tipte hileli ve iki tipte taklit taze kaşar peyniri üretilmiştir. Hileli taze kaşar üre­timlerinde elastik telemeye, her birinin erimiş kitledeki oranı %5 olacak şekilde rennet kazein, sodium kazeinat, kalsiyum kazeinat ve soya proteini izolatı katılmıştır (sırasıyla CRC, CSC, CCC, CSOY. Birinci parti taklit peynirlerin (R1 üretiminde rennet kazein, soya proteini izolatı, hidrojene pamuk yağı, NaCl, carrageenan, emülgatör, ikinci parti taklit peynirlerin (R2 üretiminde ise NaCl, modifiye nişasta, hidrojene pamuk yağı, su ve emülgatör kullanılmıştır. Kontrol amacıyla yerel bir süt işletmesinden taze kaşar pey­nirleri temin edilmiştir. Tüm peynir örneklerinde fizikokimyasal analizler, tekstür profil analizleri ve erime analizleri yapılmıştır. Taklit taze kaşar gruplarının kontrol ile karşılaştırıldığında, kurumadde (P<0.01 ve protein (P<0.01 içeriğinin daha düşük, kurumadde yağ içeriğinin ise daha yüksek olduğu görülmüştür (P<0.01. Tekstürel özellikler ve eriyebilirlik açısından en iyi sonuçlar rennet kazein içeren grup ve R2 grup­larında elde edilmiştir.

  10. Thermal expansion behavior of fluor-chlorapatite crystalline solutions

    Science.gov (United States)

    Hovis, G.; Harlov, D.; Gottschalk, M.; Hudacek, W.; Wildermuth, S.

    2009-04-01

    Apatite Ca5(PO4)3(F,Cl,OH,CO3) occurs widely as an accessory mineral in many igneous and metamorphic rocks and in nature displays a wide range of F-Cl-OH-CO3 mixtures (e.g., O'Reilly and Griffin, 2000) that have been used to interpret the role of fluids, e.g. Cl, F, and OH activities, during metamorphic and igneous processes (e.g., Harlov and Förster, 2002). It is important, therefore, to understand the thermodynamic behavior of these solid solutions, including their thermal expansion properties. Fluorapatite - chlorapatite samples were synthesized at the GFZ-Potsdam (Hovis, Harlov, Hahn and Steigert, 2007) using an adaptation of the molten flux method of Cherniak (2000). Dry CaF2 and CaCl2 (0.1 mole total) were mixed with Ca3(PO4)2 (0.03 moles), placed in a Pt crucible, equilibrated for 15 hours at 1375 °C, cooled to 1220 °C at 3 °C/hour, removed from the oven and cooled in air. Crystals were separated from the flux by boiling the quenched product in water. F:Cl fractions for each sample were determined via Rietveld refinement of X-ray powder diffraction data. Chemical homogeneity was confirmed by Rietveld refinement and high-contrast back-scattered electron imaging. Room-temperature unit-cell volumes were determined at the GFZ-Potsdam through Rietveld analysis of X-ray powder diffraction data and also at Lafayette College by standard unit-cell refinement techniques (Holland and Redfern, 1997) using NBS/NIST 640a Si as an internal standard. High-temperature unit-cell dimensions were calculated from X-ray powder diffraction data collected at Cambridge University from room temperature to 1000 °C on a Bruker D8 X-ray diffractometer. NBS Si again was utilized as an internal standard; high-temperature Si peak positions were taken from Parrish (1953). Results indicate that despite the considerable size difference between fluorine and chlorine ions, reflected by substantially different unit-cell sizes at room temperature, the coefficient of thermal expansion across

  11. Duygusal Zeka Din Öğretimi; Din Kültürü ve Ahlak Bilgisi Dersi ve Duygusal Zeka Gelişim İlişkisi

    Directory of Open Access Journals (Sweden)

    Remziye Ege

    2015-11-01

    Full Text Available Duygusal zeka, bireyin, kendi duygularını anlaması, başkalarıın duygularına empati  beslemesi, duygu yönetimi, motivasyon ve duygularını yaşamı zenginleştirecek biçimde düzenleyebilme yetisi olarak tanımlanmaktadır. Din öğretimi yoluyla duygusal zeka becerilerinin ve yerisinin elde edileceği ve geliştirileceği düşünülmektedir. Bu makalede İlköğretim Din Kültürü ve Ahlak Bilgisi Dersinin muhtevasından hareketle duygusal zeka gelişimi ile din öğretimi arasındaki paralel ilişkiye dikkat çekmek hedeflenmiştir. Söz konusu ilişki, din öğretiminin inanç, ibadet, dua, ahlak öğretim alanlarındaki konulardan örnekler üzerinde belirtilmiştir. Duygusal zeka, bireyin, kendi duygularını anlaması, başkalannın duygulanna empati beslemesi, duygu yönetimi, motivasyon ve duygularını yaşamı zenginleştirecek biçimde düzenleyebilme yetisi olarak tanımlanmaktadır. Din öğretimi yoluyla duygusal zeka becerilerinin ve yerisinin elde edileceği ve geliştirileceği düşünülmektedir. Bu makalede İlköğretim Din Kültürü ve Ahlak Bilgisi Dersinin muhtevasından hareketle duygusal zeka gelişimi ile din öğretimi arasındaki paralel ilişkiye dikkat çekmek hedeflenmiştir. Söz konusu ilişki, din öğretiminin inanç, ibadet, dua, ahlak öğretim alanlarındaki konulardan örnekler üzerinde belirtilmiştir

  12. Impact of rapid maxillary expansion on nasomaxillary complex volume in mouth-breathers

    Directory of Open Access Journals (Sweden)

    Mario Cappellette Jr.

    Full Text Available ABSTRACT Objective: To assess the volumetric changes that occur in the nasomaxillary complex of mouth-breathing patients with transverse maxillary deficiency subjected to rapid maxillary expansion (RME. Methods: This was a controlled, prospective intervention study involving 38 mouth-breathing patients presenting with transverse maxillary deficiency, regardless of malocclusion type or race. Twenty-three of them comprised the experimental group, which was composed of 11 (47.8% boys, and 12 (52.2% girls, with a mean age of 9.6 years, ranging from 6.4 to 14.2 years and standard deviation of 2.3 years; and 15 of them comprised the control group, composed of 9 (60% boys and 6 (40% girls with an mean age of 10.5 years, ranging from 8.0 to 13.6 years, and standard deviation of 1.9 years. All patients were scanned (CT according to a standard protocol: Initial CT (T1, and CT three months thereafter (T2, and the patients in the experimental group were treated with RME using a Hyrax expander for the correction of maxillary deficiency during the T1-T2 interval. The CT scans were manipulated using Dolphin® Imaging version 11.7 software for total and partial volumetric assessment of the nasomaxillary complex. Results: The results revealed that in the experimental group there was a significant increase in the size of the structures of interest compared to the control group, both in general aspect and in specific regions. Conclusions: Rapid maxillary expansion (RME provided a significant expansion in all the structures of the nasomaxillary complex (nasal cavity, oropharynx, right and left maxillary sinuses.

  13. Cevher Hazırlama ve Proses Metalurjisi ile İlgili Anılar 3. BÖLÜM Bakır, Kobalt, Çinko ve Nikel Metalürjisi ve Öğrenim Üzerine Notlar

    OpenAIRE

    REY, Maurice; KARAHAN, Sabri

    1989-01-01

    1930 yılından önce Katanga'da bakır ve kobalt üzerine yapılan hidrometalurjik araştırmalar, liç tesislerinden atılan artıklardan seçimli çöktürme yoluyla metal eldesini ve uranyum cevherlerinin hidroklorik asitle liç edilmesini içermektedir. Liége'de, 1932-1939 yılları arasında, çinko elektrolizinde kurşun anodların korozyonu ve eser miktardaki kobaltın etkisi araştırılmış, daha sonra da Yeni Kaledonya'dan getirilen yüksek tenörlü nikel matlarının elektrolitik rafinasyonu incel...

  14. KALİTELİ UYKU VE UYKU BOZUKLUKLARI / QUALITY SLEEP AND SLEEP DISORDERS

    OpenAIRE

    Algın, Demet; Akdağ, Gönül; Erdinç, Oğuz

    2018-01-01

    Özet: Uyku sağlık ve yaşamımızın iyi bir şekilde devamı için önemli bir role sahiptir. Kaliteli uyku zihinsel sağlığımızı, fiziksel sağlığımızı, hayat kalitemizı korumamıza yardım eder ve güvenliğimiz için gereklidir. Uykunun başlatılması ve sürdürülmesi kortikal ve subkortikal birçok beyin bölgesinin işlevi ile gerçekleşir. Uykunun başlatılmasında öncelikle ön hipotalamustan gelen döngüsel girdiler ve endojen kimyasal uyarılar doğrultusunda hipotalamusta ventrolateral preoptik çekirdeğin rol...

  15. BAĞDA SİLKME VE SİLKMEYE NEDEN OLAN FAKTÖRLER

    OpenAIRE

    BAHAR, ELMAN; KORKUTAL, İLKNUR; DOĞAN, AHU ZÜBEYDE

    2009-01-01

    Bağda görülen önemli problemlerden biri olan silkme üzerine birçok çalışma yapılmıştır. Bu derleme ile tür ve çeşitlerin fizyolojik ve genetik özellikleri, toprak koşulları, iklim, hastalık ve zararlılar ile yetersiz ve hatalı kültürel işlemler sonucu meydana gelen silkmenin nedenleri açıklanmaya çalışılmıştır. Bu kapsamda; fizyolojik kökenli silkme başlığı altında; asmanın gelişme kuvveti, kusurlu çiçek yapısı, yetersiz tozlanma ve döllenme üzerinde durulmuştur. İklim kökenli silkme ana başl...

  16. Küreselleşme ve Yeni Uluslararası Ekonomik Düzen

    OpenAIRE

    GÜRKAN, ÖMER

    2001-01-01

    Son dönemlerin çok sık duyduğumuz sözcüklerinden biri “küreselleşme”, bazen ekonomik ilişkilerin yoğunlaşması, mal ve hizmetlerle emek ve sermayenin artan bir serbestlikle tüm dünyada dolaşması, bazen kültür, inanç ve ideallerin benzeşmesi olarak tanımlanmaktadır. Çok genel bir ifadeyle, küreselleşme, her tür değer ve birikimin ulusal sınırları aşarak dünya çapında yaygınlaşması şeklinde, tanımlanabilir. Ekonomik açıdan bakıldığında ise, küreselleşme, üretim, ticaret ve sermaye ile işgücü ha...

  17. Thermal expansion and lattice parameters of shaped metal deposited Ti-6Al-4V

    Energy Technology Data Exchange (ETDEWEB)

    Swarnakar, Akhilesh Kumar; Van der Biest, Omer [Katholieke Universiteit Leuven, MTM, Kasteelpark Arenberg 44, 3001 Leuven (Belgium); Baufeld, Bernd, E-mail: b.baufeld@sheffield.ac.uk [Katholieke Universiteit Leuven, MTM, Kasteelpark Arenberg 44, 3001 Leuven (Belgium)

    2011-02-10

    Research highlights: > Measurement of thermal expansion and of the lattice parameters of Ti-6Al-4V fabricated by shaped metal deposition up to 1100 {sup o}C. > The observation of alpha to beta transformation not reflected in the expansion but in the contraction curve is explained by non-equilibrium alpha phase of the SMD material. > Denuding of the {alpha} phase and enrichment of the {beta} phase of Vanadium due to high temperature experiments. > The unit cell volumes derived from lattice parameters measured by X-ray diffraction are at room temperature larger for the {alpha} than for the {beta} phase. With increasing temperature the unit cell volume of the {beta} phase increases stronger than the one of the {alpha} phase resulting in a similar unit cell volume at the {beta} transus temperature. - Abstract: Thermal expansion and lattice parameters are investigated up to 1100 deg. C for Ti-6Al-4V components, fabricated by shaped metal deposition. This is a novel additive layer manufacturing technique where near net-shape components are built by tungsten inert gas welding. The as-fabricated SMD Ti-6Al-4V components exhibit a constant coefficient of thermal expansion of 1.17 x 10{sup -5} K{sup -1} during heating up to 1100 {sup o}C, not reflecting the {alpha} to {beta} phase transformation. During cooling a stalling of the contraction is observed starting at the {beta} transus temperature. These high temperature experiments denude the {alpha} phase of V and enrich the {beta} phase. The development of the lattice parameters in dependence on temperature are observed with high temperature X-ray diffraction. The unit cell volumes derived from these parameters are at room temperature larger for the {alpha} than for the {beta} phase. With increasing temperature the unit cell volume of the {beta} phase increases stronger than the one of the {alpha} phase resulting in a similar unit cell volume at the {beta} transus temperature. These observations are interpreted as an

  18. Veri Transferi Ve İşlem Güvenliğinin Sağlanmasında Kullanılan Şifreleme Yöntemleri Ve Sayısal İmza

    OpenAIRE

    ANBAR, Adem

    2004-01-01

    İnternetin ve e-ticaretin gelişmesi ve yaygınlaşması, güvenlik problemlerinin çözümüyle yakından ilişkilidir. Güvenlik sorununu; yetkilendirme, www (world wide web) güvenliği ve veri-işlem güvenliği olmak üzere üç açıdan inceleyebiliriz. Bu çalışmada, yetkilendirme ve www güvenliğine kısaca değinildikten sonra, veri-işlem güvenliği üzerinde ayrıntılı olarak durularak, veri işlem güvenliğinde kullanılan, kriptografi, onay kurumu, elektronik noter, elektronik ve sayısal imza gibi yeni güvenlik ...

  19. Corium Spreading Over Concrete: The Vulcano VE-U7 and VE-U8 Tests

    International Nuclear Information System (INIS)

    Journeau, Christophe; Boccaccio, Eric; Fouquart, Pascal; Jegou, Claude; Piluso, Pascal

    2002-01-01

    Two experiments have been performed in the VULCANO facility in which prototypic corium has been spread over concrete. In the VE-U7 test, a mixture representative of what can be expected at the opening of EPR reactor-pit gate has been spread on siliceous concrete and on a reference channel in inert refractory ceramic. The spreading progression was not much affected by the presence of concrete and sparging gases. In the VE-U8 test, a UO 2 -ZrO 2 mixture, prototypic of in-vessel corium, has been spread over a lime-siliceous concrete. Although residual power was not simulated in this experiment, up to 2 cm of concrete have been eroded during the test. Results in terms of spreading behaviour, effects of gases, concrete erosion and thermal attack are presented and discussed. (authors)

  20. Tanshinon IIA injection accelerates tissue expansion by reducing the formation of the fibrous capsule.

    Science.gov (United States)

    Yu, Qingxiong; Sheng, Lingling; Yang, Mei; Zhu, Ming; Huang, Xiaolu; Li, Qingfeng

    2014-01-01

    The tissue expansion technique has been applied to obtain new skin tissue to repair large defects in clinical practice. The implantation of tissue expander could initiate a host response to foreign body (FBR), which leads to fibrotic encapsulation around the expander and prolongs the period of tissue expansion. Tanshinon IIA (Tan IIA) has been shown to have anti-inflammation and immunoregulation effect. The rat tissue expansion model was used in this study to observe whether Tan IIA injection systematically could inhibit the FBR to reduce fibrous capsule formation and accelerate the process of tissue expansion. Forty-eight rats were randomly divided into the Tan IIA group and control group with 24 rats in each group. The expansion was conducted twice a week to maintain a capsule pressure of 60 mmHg. The expansion volume and expanded area were measured. The expanded tissue in the two groups was harvested, and histological staining was performed; proinflammatory cytokines such as tumor necrosis factor-α (TNF-α), interleukin-6 (IL-6) and interleukin-1β (IL-1β) and transforming growth factor-β (TGF-β) were examined. The expansion volume and the expanded area in the Tan IIA group were greater than that of the control group. The thickness of the fibrous capsule in the Tan IIA group was reduced with no influence on the normal skin regeneration. Decreased infiltration of macrophages, lower level of TNF-α, IL-6, IL-1β and TGF-β, less proliferating myofibroblasts and enhanced neovascularization were observed in the Tan IIA group. Our findings indicated that the Tan IIA injection reduced the formation of the fibrous capsule and accelerated the process of tissue expansion by inhibiting the FBR.

  1. Tanshinon IIA injection accelerates tissue expansion by reducing the formation of the fibrous capsule.

    Directory of Open Access Journals (Sweden)

    Qingxiong Yu

    Full Text Available The tissue expansion technique has been applied to obtain new skin tissue to repair large defects in clinical practice. The implantation of tissue expander could initiate a host response to foreign body (FBR, which leads to fibrotic encapsulation around the expander and prolongs the period of tissue expansion. Tanshinon IIA (Tan IIA has been shown to have anti-inflammation and immunoregulation effect. The rat tissue expansion model was used in this study to observe whether Tan IIA injection systematically could inhibit the FBR to reduce fibrous capsule formation and accelerate the process of tissue expansion. Forty-eight rats were randomly divided into the Tan IIA group and control group with 24 rats in each group. The expansion was conducted twice a week to maintain a capsule pressure of 60 mmHg. The expansion volume and expanded area were measured. The expanded tissue in the two groups was harvested, and histological staining was performed; proinflammatory cytokines such as tumor necrosis factor-α (TNF-α, interleukin-6 (IL-6 and interleukin-1β (IL-1β and transforming growth factor-β (TGF-β were examined. The expansion volume and the expanded area in the Tan IIA group were greater than that of the control group. The thickness of the fibrous capsule in the Tan IIA group was reduced with no influence on the normal skin regeneration. Decreased infiltration of macrophages, lower level of TNF-α, IL-6, IL-1β and TGF-β, less proliferating myofibroblasts and enhanced neovascularization were observed in the Tan IIA group. Our findings indicated that the Tan IIA injection reduced the formation of the fibrous capsule and accelerated the process of tissue expansion by inhibiting the FBR.

  2. Ülkemizde Yetiştirilen Başlıca Buğday Çeşitlerinin ve Unlarının Tiamin ve Riboflavin Miktarları

    Directory of Open Access Journals (Sweden)

    Recai Ercan

    2015-02-01

    Full Text Available Bu çalışmada, ülkemizde yetiştirilen başlıca buğday çeşitlerinin ve bunların laboratuvar değirmeninde öğütülmesiyle elde edilen unlarının B1 ve B2 vitaminleri miktarı saptanmıştır. Araştırmada 18 buğday çeşidi kullanılmıştır. Buğdaylarda B1 ve B2 vitaminleri miktarı çeşit ve yetişme yerine bağlı olarak değişmektedir. Genellikle sert buğdaylar, yumuşaklardan daha zengin bulunmuştur. Unlarda B1 ve B2 vitamin miktarlarının buğday çeşidi ve randımanı ile ilişkili olduğu görülmüştür. Un randımanı arttıkça vitamin miktarları da artmaktadır.

  3. Sinemada uyarlama sorunsalı ve auteur bir yönetmen olarak Aki Kaurismaki

    OpenAIRE

    Mirza, Ayşe

    2016-01-01

    Bu çalışmada Aki Kaurismaki’nin Suç ve Ceza (Rikos ja rangaistus, 1983), Hamlet Goes Business (Hamlet liikemaailmassa, 1987) ve Kibritçi Kız (Tulitikkutehtaan tyttö, 1990) adlı uyarlama filmleri, auteur kuram ve minimalist üslup açısından incelenecektir. Bu bağlamda filmlerin analizlerine geçilmeden önce, uyarlama filmlerin tarihsel gelişimi ve bu konudaki tartışmalar, auteur kuram ve sinemada minimalizm konuları ele alınacak, ardından ilgili filmler betimleyici analiz yoluyla değerlendirilec...

  4. Salicornia, Sarcocornia ve Arthrocnemum cinslerinin (Chenopodiaceae) Türkiye taksonomik revizyonu

    OpenAIRE

    YAPRAK, Ahmet Emre

    2008-01-01

    Bu çalışmada Türkiye’de bulunan Salicornia L., Sarcocornia A. J. Scott ve Arthrocnemum Moq. cinslerine ait türlerin morfolojik, karyolojik, biyocoğrafik özelliklerinin ve filogenetik ilişkilerinin tanımlanması amaçlanmıştır. Araştırmalar sonucunda Türkiye Florasında verilen Salicornia fragilis P. W. Ball & Tutin, Salicornia europaea L. ve Sarcocornia fruticosa &l...

  5. Unabomber: “Sanayi Toplumu ve Geleceği”

    OpenAIRE

    URAL, Mustafa Nuri; TÜRKAL, İhsan

    2015-01-01

    Ancak çok az şey toplumu Sanayi Devriminin değiştirdiği kadar köklü ve derinden değiştirmiştir. Hiç kimse isteyerek modern hayatın nimetlerinden vazgeçmeye gönüllü gözükmüyor. Ama giderek artan problemler birçok düşünce insanı tarafından yüksek sesle dile getiriliyor. Theodore John Kaczynski kitabında modern toplumun sorunlarını, teknolojinin bu bağlamdaki etkisini, çözümleri ve devrimin önündeki tehlikeleri analitik bir biçimde inceliyor. Gerek yöntemiyle gerek oluşum süreciyle ve içeriğiyle...

  6. Excess Molar Volume,Viscosity and Heat Capacity for the Mixture of 1,2—Propanediol—Water at Different Temperatures

    Institute of Scientific and Technical Information of China (English)

    杨长生; 马沛生; 唐多强; 靳凤民

    2003-01-01

    Experimental densities,viscosities and heat capacities at different emperatures were presented over the entire mole fraction range for the binary mixture of 1,2-propanediol and water,Density values were used in the determination of excess molar volumes,VE,At the same time,the excess viscosity was in vestigated,The values of VE and ηE were fitted to the Redlich-kister equation.Good agreement was observed,The excess volumes are negative over the entire range of composition.They show an U-shaped-concentration dependence and decrease in abolute values with increase of temperature,Values of ηE are negative over the entire range of the composition,and has a trend very similar to that of VE ,The analysis shows that at any temperature the specific heat of mixture is a linear function of the composition as x1>20%,All the extended lines intersect at one point.An empirical equation is obtained to calculate the specific heat to mixture at any composition and temperature in the experimental range.

  7. Membran Distilasyon ve Ozmotik Distilasyon ile Meyve Suyu Konsantrasyonu

    Directory of Open Access Journals (Sweden)

    Pelin Onsekizoğlu

    2015-02-01

    Full Text Available Geleneksel termal evaporasyonla meyve suyu konsantresi üretiminde uygulanan yüksek sıcaklıklar, uçucu aroma maddeleri, vitaminler ve diğer besin öğelerinde kayıplar, pişmiş tat oluşumu, renk bozulması ve insan sağlığı üzerinde olumsuz etkilere neden olmaktadır. Geleneksel uygulamaların yerini almak üzere, hem iyi kalitede hem de güvenilir ürün üretimine olanak tanıyan alternatif konsantrasyon teknolojileri gün geçtikçe önem kazanmaktadır. Bu teknolojiler arasında, membran distilasyon ve ozmotik distilasyon gibi membran uygulamaları meyve sularının oda sıcaklığında veya buna yakın sıcaklıklarda 60-65 ˚Briks ve hatta daha yüksek seviyelere konsantrasyonuna olanak sağlamaları bakımından ön plana çıkmışlardır. Çalışmada, taze ürün karakteristiklerine yakın ürün üretiminde gelecek vadeden bu membran uygulamalarının temel ilkeleri ve meyve suyu sanayinde kullanım potansiyelleri hakkında bilgi verilmiştir.

  8. Blood Volume: Importance and Adaptations to Exercise Training, Environmental Stresses and Trauma Sickness

    Science.gov (United States)

    2000-02-01

    because of limb atrophy, weight loss, and inactivity) because erythro- cyte levels of 2,3- diphosphoglycerate (2,3-DPG) were in- creased. However...blood volume expansion during exercise training may partially be explained by factors such as initial fitness level , training intensity, exercise mode...335 and their hydration level when measurements are made (131). Plasma volume expansion seems to be greatest when performing upright exercise on about

  9. Fully resolved simulations of expansion waves propagating into particle beds

    Science.gov (United States)

    Marjanovic, Goran; Hackl, Jason; Annamalai, Subramanian; Jackson, Thomas; Balachandar, S.

    2017-11-01

    There is a tremendous amount of research that has been done on compression waves and shock waves moving over particles but very little concerning expansion waves. Using 3-D direct numerical simulations, this study will explore expansion waves propagating into fully resolved particle beds of varying volume fractions and geometric arrangements. The objectives of these simulations are as follows: 1) To fully resolve all (1-way coupled) forces on the particles in a time varying flow and 2) to verify state-of-the-art drag models for such complex flows. We will explore a range of volume fractions, from very low ones that are similar to single particle flows, to higher ones where nozzling effects are observed between neighboring particles. Further, we will explore two geometric arrangements: body centered cubic and face centered cubic. We will quantify the effects that volume fraction and geometric arrangement plays on the drag forces and flow fields experienced by the particles. These results will then be compared to theoretical predictions from a model based on the generalized Faxen's theorem. This work was supported in part by the U.S. Department of Energy under the Predictive Science Academic Alliance Program, under Contract No. DE-NA0002378.

  10. Artvin, Rize ve Trabzon’daki Doğal Kaynak Sularında Toplam Alfa, Toplam Beta Aktivite Değerlerinin Belirlenmesi ve Jeoistatistiksel Olarak Modellenmesi

    Directory of Open Access Journals (Sweden)

    Yaşar Kobya

    2014-11-01

    Full Text Available Trabzon, Rize ve Artvin yaklaşık 18000km2 alan üzerine kurulmuş ve yaklaşık 2 milyon insanın yaşadığı Türkiye’nin en kuzey doğusunda bulunan üç ildir. Bu üç ilde toplam 20 tane içme suyu kaynağından örnekler alındı ve bunların toplam alfa, toplam beta aktivite değerleri Berthold LB770 marka alfa, beta sayım cihazı kullanılarak belirlendi. Toplam alfa aktivite değerleri 1.7-114.2 Bq/L ve toplam beta aktivite değerleri ise 2.9-90.8 Bq/L aralıklarında ölçüldü. Bulunan bu değerler dünya sağlık örgütü (WHO’nün limit değerleri ve yapılmış diğer benzer çalışmalarla karşılaştırıldı. Elde edilen veriler için klasik istatistik hesaplamalar yapıldı. Ayrıca jeoistatistik analiz yöntemi kullanılarak eş-doz eğrileri oluşturuldu ve harita üzerinde gösterilerek bölge için bir risk haritası oluşturuldu.

  11. KADIN YOKSULLUĞU VE KADIN SAĞLIĞI ÜZERİNE YANSIMALARI

    Directory of Open Access Journals (Sweden)

    Seda KOCABACAK

    2014-08-01

    Full Text Available Cinsiyet eşitsizliği, yoksulluk ve iyi olmayan sağlık durumunun önemli nedenlerinden biridir. Kadınlar sosyal hayatın birçok alanında cinsiyet ayrımcılığı ile karşı karşıya kalırlar: sağlık hizmetlerinden yararlanma, eğitim, istihdam koşulları, sosyal ve ekonomik yaşam, politik haklar ve ahlaki sorumluluklar bunların bazılarıdır. Bazı toplumsal kabuller ya da ailelerin ekonomik zorlukları kız çocukların okuldan uzak kalmasına yol açabilmektedir. Eğitimsizlik ya da yetersiz eğitim ise özel nitelikler gerektirmeyen ya da düşük gelir sağlayan işlerde çalışılmasına yol açmaktadır. Bu kısıtlılıklar ve eşitsizlikler kadın sağlığı ve refahı üzerinde doğrudan ya da dolaylı etkilere sahiptir. Eğitimli ve refah sahibi kadınlar kadın sağlığı, çocuk sağlığı, aile sağlığı ve hatta tüm toplumun sağlığının geliştirilmesine katkı sağlarlar. Bu çalışmanın amacı ilk olarak kadın yoksulluğu ve sağlığı arasındaki ilişkiyi tartışmak ve Türkiye’ye ilişkin verilerle değerlendirmeler yapmaktır.

  12. Konya Kültür ve Tarihi Açısından Anıt Dergisi Anit Journal In Terms Of Culture And History Of Konya

    Directory of Open Access Journals (Sweden)

    Muammer ULUTÜRK

    2013-03-01

    Full Text Available Anıt (Monument is a archeology, folklore and history journalpublished, but irregular intervals, by “Konya and Nearby Vicinity OldArts Lovers Association” from February 1949 until March 1964. AnıtJournal possesses the features which worth to be examined with regardto the fact that it will shed light to the history of Konya and its vicinityespecially with its manuscripts comprising many fields such as history,historical geography, foundation certificates, architecture, places ofworship, bibliographies, ethnography, archaeology, folklore, philosophy, city history, Mevlana and Mesnevi. Anıt Journal was published 31volumes in total in irregular intervals from February 1949 until March1964. The journal, which published its 19th volume in July 1950, wasable to publish the 20th volume in April 1957 after a long interval, andput the final point to its publication life with last volume in March 1964.The journal filled an important gap by means of authors andmanuscripts providing significant contributions for cultural heritageespecially in Konya and its vicinity. Not only did the associationpublished the journal but also materialized the restorations of real estatecultural assets in Konya city centre as stated in its regulations withfinancial and spiritual support of helpful Konya people. Restorations ofthe lead covers of Selimiye and Kapı Mosques, repair of tombs of Sems-iTebrizi, Emir Ishak and Sheikh Aleman, saving Abdulaziz, Zenburi,Beyhekim and Tercuman small mosques, repair of mosque extension roofand the yard Wall of Sahip Ata complex are only some of thesecontributions. When looked from today’s perspective, we believe that thecontent and index of the journal that conveys to be a historical documentwill provide great contributions for those who carry out studies in thefield of social sciences. Anıt, “Konya ve Mülhakâtı Eski Eserleri Sevenler Derneği”tarafından 1949 yılının Şubatından, 1964 yılının Martına kadar ayl

  13. MARGUERITE YOURCENAR’IN ATEŞLER VE DÜŞ PARASI ADLI YAPITLARINDA MİTOLOJİ VE METİNLERARASILIK / MYTHOLOGY AND INTERTEXTUALITY IN MARGUERITE YOURCENAR’S WORKS ATEŞLER AND DÜŞ PARASI

    Directory of Open Access Journals (Sweden)

    Esra BÜYÜKŞAHİN

    2016-06-01

    Full Text Available Mitos insanda varlık düşüncesinin ve dilin gelişimi ile birlikte ortaya çıkmış ve bu ikisi gibi insanın en temel zihinsel etkinliklerinin birer parçası olmuştur. Tarihsel çizgisellik içinde ilkel insan topluluklarından Ortaçağ toplumlarına, sanayileşmiş toplumlara ve günümüz toplumlarına kadar bütün topluluklar kendi mitlerini yaratmış ya da var olan mitleri güncelleyerek onları benimsemiş ve izlemiştir. Mitosun her dönemde canlılığını ve devimselliğini koruması şüphesiz onun ayrım gözetmeksizin her insanda aynı zihinsel gereksinime (varlığını anlamlandırma, kendini evren içinde konumlandırma gereksinimine karşılık gelmesinden kaynaklanmaktadır. Her dönemde ve her bireyde etkili olduğu düşünülen mitosun sanat ve yazında izlerinin bulunmaması olası değildir. Mitos, hem derin simgesel anlamıyla hem de pek çok yazınsal türe ve yoruma uyum sağlayabilen esnek yapısıyla tarih boyunca yazar ve sanatçıları için esin kaynağı olagelmiştir. Batı yazınının temeli sayılan Yunan ve Roma yazınlarının mitolojiyi esas aldığı düşünüldüğünde mitosun Batı yazınındaki önemli yeri de anlaşılır. Yazarlar mitosa çoğunlukla metinlerarasılığın yöntemlerini kullanarak başvurmuşlardır. Böylece mitosu da kendilerinin ve yaşadıkları dönemin estetik anlayışı ve koşullarına göre yeniden güncellemişlerdir. Bu sayede hem mitos yeni anlamlarla ve simgelerle donanarak zenginleşir hem de yapıt mitosun simgeselliğinden yararlanarak çokanlamlı ve evrensel bir boyut kazanır. Yirminci yüzyıl Fransız yazınının en dikkat çekici kadın yazarlarından olan Marguerite Yourcenar da mitosa başvurmaktan çekinmemiş; pek çok yapıtında onu eğip bükerek, bilinen anlamlarından kopararak ya da bunlara yenilerini ekleyerek mitosun sunduğu geniş anlam olanaklarından faydalanmış, kendi anlatımında sıkça yer vermiştir. Bu çalışmada Marguerite

  14. Superior Mezenter Arter Embolisinde Erken Tanı ve Embolektomi

    OpenAIRE

    AYDIN, İbrahim; YÜCEL, Ahmet; PERGEL, Ahmet; KARAKAYA, Ahmet; OĞULLAR, Sabri; ŞAHİN, Dursun; ÖZER, Ender

    2016-01-01

    Akut mezenter arter embolisi, acil girişim gerektiren, nekroz geliştiğinde yaygın ince barsak rezeksiyonu ve sonrasında gelişen kısa barsak sendromu nedeniyle yaşam kalitesini düşüren, morbidite ve mortalitesi oldukça yüksek bir hastalıktır. Multidetektör kontrastlı BT, akut mezenterik embolinin erken tanısında oldukça önemlidir. Biz burada, kontrastlı abdominal BT ile erken tanı ve sonrasında bağırsak rezeksiyonu gerekmeden yalnızca embolektomi yaparak tedavi ettiğimiz olguyu sunmayı amaçlad...

  15. Küf Koleksiyonlarının Oluşturulması ve Korunumu

    Directory of Open Access Journals (Sweden)

    Şeminur Topal

    2015-02-01

    Full Text Available Çeşitli amaçlarla saf küf kültürlerinin uygun koşullarda ve özgün karakterlerini değiştirmeden korunmasını esas alan küf koleksiyonunun varlığı pek çok durum ve kuruluşun çalışmalarına destek sağlayabilir. Bu gerçekten hareketle NATO destekli ve 6 yıl süren Türkiye’de çeşitli tarımsal ürün ve gıdaların tarladan-tüketime kadarki küf floralarının taranmasına yönelik proje çalışmasında izole ve identifiye edilen küflerin bir koleksiyon bünyesinde değerlendirilmesi planlanmıştır. Pek çoğu, önemli dış koleksiyon merkezleri olan CBS-Hollanda ve CMI-İngiltere’deki uzmanların teyidini alan ve identifikasyonları tarafımızdan yapılan 10.000 civarındaki küf izolatından duplikasyon yaratabilecekleri elemine edilmiş, diğerleri korunuma alınmıştır. Yatık ve liyofilize kültürler olarak koleksiyonda bulunan küf suşlarının büyük bir kısmı için sistematik arşivleme çalışması tamamlanmış ve bilgisayar yardımı ile sınıflandırılmıştır. Bu sınıflama mevcut küflerin, izole edildiği örnek cinsi ve kayıt numaralarına, sağlandığı bölgelerin il trafik kod numaralarına, küf kültürlerinin cins ve tür isimlerine, liyofilize numaralarına ve koleksiyon odasındaki konumunun yer numaralarına göre olmak üzere 6 ayrı parametre için tek tek yapılarak arşivleme gerçekleştirilmiştir. Ayrıca identifiye edilen küflerin cins ve türlerine göre kartoteksleme işlemi yapılmıştır. Bu çalışmada koleksiyon ve korunumuna ilişkin ayrıntılı bilgiler verilmiştir.

  16. ETANOL + 1-NONANOL İKİLİ SİSTEMİ VE ETANOL + 1-NONANOL + SU ÜÇLÜ SİSTEMİNİN 293.15 K SICAKLIKTAKİ YOĞUNLUKLARININ, REFRAKTİF İNDİSLERİN ÖLÇÜLMESİ VE AŞIRI MOLAR HACİMLERİNİN VE MOLAR REFRAKSİYONLARININ HESAPLANMASI

    OpenAIRE

    MAHRAMANLIOĞLU, Mehmet; KIRBAŞLAR, Ş. İsmail

    2000-01-01

    Etanol+1-nonanol ikili sistemi ve etanol+1-nonanol+su üçlü sistemi için çeşitli karışımlarda yoğunluklar ve kırılma indisleri 293.15 K de ölçülmüştür. İkili ve üçlü sistemler için aşırı molar hacim ve molar refraksiyon sapmaları hesaplanmıştır. Aşırı molar hacim ve molar refraksiyon sapmaları için Redlich–Kister eşitliği uygulanarak eşitlik katsayıları hesaplanmıştır.

  17. Evaluation of tank thermal expansion data in CALDEX

    International Nuclear Information System (INIS)

    Suda, S.; Weh, R.

    1991-01-01

    A thermal expansion test involving a large annular input reprocessing tank was carried out as a part of the CALDEX Project at the TEKO test facility in Karlsruhe, FRG. The objective of this test was to investigate thermal expansion properties of the tank and effects on various pressure and level measurement instruments used in the determination of liquid volume. In the thermal expansion test, a weak nitric acid solution was heated internally to a temperature of 60 degrees C by means of steam injection through the sparge ring. After heating, the annular tank took about one hour to thermally equilibrate, and it took another hour for the sparge ring and pulsator pipes to fill before thermal effects could be followed. The temperature at the end of the test, after tank and its contents had cooled undisturbed for fifty hours, was 29.9 degrees C. Thirteen instrument readings were obtained during each measurement cycle of roughly 70 seconds for a total of over 2800 readings per instrument. Thermal expansion effects for the CALDEX annular tank were consistent with that reported for cylindrical tanks. Temperature variations effect each type of probe in a way that depends on the properties of the probe and the characteristics of the measurement system. 3 refs., 4 figs., 3 tabs

  18. Patrick Mccabe’in Plüton’da Kahvaltı ve Jeffrey Eugenides’in Middlesex adlı romanlarında cinsel kimlik, aile ve göç

    OpenAIRE

    DEMİR, Elif

    2016-01-01

    Cinsiyet  ve  toplumsal  cinsiyet  kavramları  merak  ve  ilham  uyandıran  yapısıyla  pek  çok  bilimsel  alanın  ilgi  konusu  olmuş  ve  kadın/erkek  ikiliği  dışına  çıkan  bireylere  atfedilen  ‘queer’  kavramıyla  edebi  imgelemde &nbs...

  19. LANCHESTER DOĞRUSALLIK KANUNU VE BİR PAZARLAMA UYGULAMASI

    OpenAIRE

    YARALIOĞLU, KAAN

    2001-01-01

    Bu çalışmada birebir mücadeleler için geliştirilen Lanchester’ in Doğrusallık Kanunu incelenmiştir. Öncelikle formülasyon ve kullanılabilirlik koşulları tanımlanmış ve bir pazarlama uygulaması gerçekleştirilmiştir.

  20. Laktoperoksidaz Sistemin Aktivasyonuyla ve Soğutularak Korunan Sütlerin Mikrobiyolojik Özellikleri

    Directory of Open Access Journals (Sweden)

    Zerrin Erginkaya

    2015-02-01

    Full Text Available Araştırmada, 12:8 mg/l ve 24:16 mg/l Tiyosiyanat: Hidrojenperoksit (SCN:H2O2 ilavesi ile laktoperoksidaz sistemi aktive edilen sütler 30°C'de 6 saat süreyle bekletilmişlerdir. Soğutularak 4±1°C'de tutulan, ayrıca kontrol olarak da SCN:H2O2 katılmamış ve 30°C'de tutulan süt örnekleri de aynı süre bekletilmişlerdir. Bekletmenin 0., 3. ve 6. saatlerinde sütün pH değeri, asittik derecesi ve bazı mikroorganizma grubu içeriklerindeki değişimler incelenmiştir. Laktoperoksidaz sisteminin aktivasyonunun, sütlerin toplam aerob mezofil ve psikrotrof bakteri gruplarının, mezofil ve termofil laktik asit bakteri gruplarının, enterobakterlerin ve küf-mayaların gelişimini önemli düzeyde etkilediği görülmüştür (p<0,05. Soğutmanın da toplam aerob psikrotrof bakteriler dışında, incelenen diğer tüm mikroorganizma gruplarını önemli düzeyde etkilediği bulunmuştur. SCN:H2O2 konsantrasyonunun artmasının, sistemin antimikrobiyel etkisini artırdığı belirlenmiştir. Laktoperoksidaz sisteminin aktivasyonunun soğutma kadar etkin olduğu, toplam aerob mezofil ve psikrotrof bakterilerle, enterobakterler üzerinde soğutmadan daha fazla etkili olduğu görülmüştür. Soğutma işlemi ve laktoperoksidaz sisteminin aktivasyonu, sütlerin pH ve asitlik değerleri üzerinde önemli ve yaklaşık aynı düzeyde etkili bulunmuştur (p<0,05.

  1. Theory of compression and expansion of hydrogels

    Energy Technology Data Exchange (ETDEWEB)

    Iwata, M. [Suzuka National College of Tech., Mie (Japan). Dept. of Industrial Chemistry; Koda, S.; Nomura, H. [Nagoya University, Nagoya (Japan). Dept. of Molecular Design and Engineering

    1999-10-01

    Compression and expansion processes of cross-linked sodium polyacrylate hydrogels under mechanical pressure were investigated. A packed spherical gel bed shows irreversible deformation when the applied pressure is decreased; the expansion behavior depends on the maximum pressure applied to the gel bed. The time required to attain a certain degree of deformation is directly proportional to the square of the total solid volume of the gel bed; this relation is very similar to that observed in expression or expansion processes of ordinary solid-liquid mixtures. The driving force of the deformation is an effective osmotic pressure gradient in the gel bed, where the effective osmotic pressure of the gel is the difference between the swelling pressure of the gel and the pressure applied to the gel. The flow rate of liquid through any gel layer can be expressed by Darcy's equation. The deformation ceases when the swelling pressure of each gel particle is equal to the applied pressure. Thus, the deformation of a packed gel bed can be recognized as a process of equalizing the swelling pressure distribution in the bed. (author)

  2. VAROLUŞ FELSEFELERİ, VAROLUŞÇU TERAPİ VE SOSYAL HİZMET

    Directory of Open Access Journals (Sweden)

    Gizem ÇELİK

    2017-07-01

    Full Text Available Öz Varoluş felsefeleri, insanı ve insan yaşamını açıklamaya çalışan felsefi akımları temel alarak; ancak onlardan farklılaşan önemli nitelikleri ile günümüz insanının sorunlarına yönelen ve tek bir tanımlamayla anılması mümkün olmayan, kimilerine göre bir felsefe yapma tarzını kimilerine göre ise bir felsefi iklimi ifade etmektedir. En yalın ifadeyle, insanı nesne gibi ele alan ve yorumlayan yaklaşımlara tepki olarak, insanın biricik ve otantik oluşu özelliği ile tanımlanması gereken bir varoluş olduğunu belirten varoluşçu görüş, pek çok insanî soruyu ele alıp işleyerek “öz-varoluş ilişkisi”, “varlığın ve hayatın anlamı”, “özgür iradenin insan davranışlarındaki rolü”, “sınırsız özgürlük ve sorumluluk”, “varoluşsal anksiyete” gibi pek çok konuda açıklamalarda bulunmaktadır. Bu çalışmada, varoluş felsefelerine ve temel niteliklerine ilişkin genel bilgilere, artan ve karmaşıklaşan insan sorunlarının çözümünde önemli açıklamalar getirmesi dolayısıyla terapide yer bulan varoluşçu analizin özelliklerine ve odağı insan, insan sorun ve ihtiyaçları olan sosyal hizmet disiplin ve mesleğinin varoluş felsefeleri ile olan ilişkisine yer verilmektedir. Abstract Without a single definition, philosophies of existence sometimes described as the “way of making philosophy” or sometimes “climate of philosophy”. It basically arose from philosophical trends which are trying to explain human and life but differentiates from them by focusing on the problems of the modern man. By the simplest terms, existential philosophy states that human being must be defined as unique and authentic existent and it has born as a reaction to the approach that takes human beings as objects. Existential philosophy takes and examines many humanitarian questions such as "self-existence relationship”, “meaning of life and the existence”, “the role of

  3. Fabrication of two-dimensional nanosheets via water freezing expansion exfoliation

    International Nuclear Information System (INIS)

    Li, Chen; Wang, Tailin; Wu, Yongzhong; Ma, Fukun; Zhao, Gang; Hao, Xiaopeng

    2014-01-01

    Layered materials, if exfoliated effectively, will exhibit several unique properties, offering great potential for diverse applications. To this end, in this study, we develop a novel, universal, and environmentally friendly method named as ‘water freezing expansion exfoliation’ for producing two-dimensional nanosheets. This method exploits the expansion in the volume of water upon freezing. When the water freezing expansion condition is reproduced in layered materials, the layers exfoliate to overcome the van der Waals force between them. The expansion process is performed by repeated cycling between 4 °C and −20 °C to effectively exfoliate layered materials of graphite, hexagonal boron nitride (h-BN), MoS 2 and WS 2 . Systematic characterization of the samples thus obtained using electron microscopy and optical studies substantiate the formation of thin flakes (graphene, h-BN, MoS 2 , and WS 2 nanosheets). The method demonstrated in this study is cost-effective and does not demand sophisticated equipment and stringent high temperature conditions. Given this general applicability, this method holds great promise for exfoliating layered materials that are sensitive to elevated temperature. (paper)

  4. Türkiye’de süs bitkileri sektörünün üretim ve yapısal sorunları ve öneriler

    OpenAIRE

    ONAY, Hatice Aslı

    2008-01-01

    ÖZET:

    Bu tez çalışması Türkiye’de süs bitkileri sektörünün üretim ve yapısal sorunlarını analiz ederek bunlara yapıcı ve sürdürülebilir çözümler üretmek amacıyla yapılmıştır. Bunun için öncelikle sektörün ülkemizdeki mevcut durumu ortaya konulmaya çalışılmıştır. Mevcut durumu ortaya koymak için ise sektörün üretim, ithalat ve ihracat verilerinden yararlanılmıştır. Birçok kurum ve kuruluşlardan edinilen bu veriler ışığında sekt...

  5. VeA of Aspergillus niger increases spore dispersing capacity by impacting conidiophore architecture.

    Science.gov (United States)

    Wang, Fengfeng; Dijksterhuis, Jan; Wyatt, Timon; Wösten, Han A B; Bleichrodt, Robert-Jan

    2015-01-01

    Aspergillus species are highly abundant fungi worldwide. Their conidia are among the most dominant fungal spores in the air. Conidia are formed in chains on the vesicle of the asexual reproductive structure called the conidiophore. Here, it is shown that the velvet protein VeA of Aspergillus niger maximizes the diameter of the vesicle and the spore chain length. The length and width of the conidiophore stalk and vesicle were reduced nearly twofold in a ΔveA strain. The latter implies a fourfold reduced surface area to develop chains of spores. Over and above this, the conidial chain length was approximately fivefold reduced. The calculated 20-fold reduction in formation of conidia by ΔveA fits the 8- to 17-fold decrease in counted spore numbers. Notably, morphology of the ΔveA conidiophores of A. niger was very similar to that of wild-type Aspergillus sydowii. This suggests that VeA is key in conidiophore architecture diversity in the fungal kingdom. The finding that biomass formation of the A. niger ΔveA strain was reduced twofold shows that VeA not only impacts dispersion capacity but also colonization capacity of A. niger.

  6. Tissue Expansion Using Hyaluronic Acid Filler for Single-Stage Ear Reconstruction: A Novel Concept for Difficult Areas.

    Science.gov (United States)

    Inbal, Amir; Lemelman, Benjamin T; Millet, Eran; Greensmith, Andrew

    2017-10-16

    Auricular reconstruction is one of the most challenging procedures in plastic surgery. An adequate skin envelope is essential for cartilage framework coverage, yet few good options exist without additional surgery. We propose a novel method for minimally invasive tissue expansion, using hyaluronic acid (HA) filler to allow for single-stage ear reconstruction. To introduce the novel concept of HA filler for tissue expansion in ear reconstruction, and as an alternative to traditional expansion techniques. Macrolane is a large particle HA gel developed for large volume restoration. Expansion of the non-hair-bearing mastoid skin was performed in our clinic weekly or every other week. Final expansion was completed one week prior to reconstructive surgery. Tissue from one patient's expanded pocket was sent for histological analysis. Ten patients underwent single-stage auricular reconstruction with preoperative expansion. Injection sessions ranged from 7 to 13 (mean, 9.7). Mean injected volume per session was 2.03 mL per patient, for an average total of 19.8 mL (range, 14.5-30 mL). There were no major complications. One minor complication required removal of exposed wire from the antihelix in the office. Hematoxylin and eosin stain revealed similar histology to that seen with traditional expanders. This novel expansion technique using serial HA injections allowed for optimized skin coverage in single-stage ear reconstruction. The concept of tissue expansion using HA filler is a new frontier for research that may be applicable to other arenas of reconstruction. 4. © 2017 The American Society for Aesthetic Plastic Surgery, Inc. Reprints and permission: journals.permissions@oup.com

  7. Bazı Şekerlemeler ve Yapay Toz İçeceklerdeki Diazo Boyar Madde Olan Sunset Yellow FCF ile Tartrazin Miktar Tayinlerinin Voltametrik ve Spektrofotometrik Metod Karşılaştırması

    Directory of Open Access Journals (Sweden)

    Nejat Altıniğne

    2015-02-01

    Full Text Available Bazı şekerlemeler ve toz içeceklere katımlı olan sunset yellow FCF ve tartrazin boyar maddelerin analizleri, voltametrik (DPP ve spektrofotometrik metotlarla yapılarak karşılaştırılmıştır. Şekerlemelerde ve sentetik toz içeceklerde boyar maddenin yalnız bir tanesi bulunduğunda, doğru, hassas ve güvenli sonuçlar elde edilebilmektedir. Uygulanan her iki metodun korelasyon sayısı r= 0.995 ve tayin sınıfları 0.8 mg/ml olarak saptanmıştır. Bu çalışma nitel ve nicel tayinlerin, spektrofotometrik metot yanında voltametri metoduyla da yapılabildiğini göstermiştir.

  8. Models for mean bonding length, melting point and lattice thermal expansion of nanoparticle materials

    International Nuclear Information System (INIS)

    Omar, M.S.

    2012-01-01

    Graphical abstract: Three models are derived to explain the nanoparticles size dependence of mean bonding length, melting temperature and lattice thermal expansion applied on Sn, Si and Au. The following figures are shown as an example for Sn nanoparticles indicates hilly applicable models for nanoparticles radius larger than 3 nm. Highlights: ► A model for a size dependent mean bonding length is derived. ► The size dependent melting point of nanoparticles is modified. ► The bulk model for lattice thermal expansion is successfully used on nanoparticles. -- Abstract: A model, based on the ratio number of surface atoms to that of its internal, is derived to calculate the size dependence of lattice volume of nanoscaled materials. The model is applied to Si, Sn and Au nanoparticles. For Si, that the lattice volume is increases from 20 Å 3 for bulk to 57 Å 3 for a 2 nm size nanocrystals. A model, for calculating melting point of nanoscaled materials, is modified by considering the effect of lattice volume. A good approach of calculating size-dependent melting point begins from the bulk state down to about 2 nm diameter nanoparticle. Both values of lattice volume and melting point obtained for nanosized materials are used to calculate lattice thermal expansion by using a formula applicable for tetrahedral semiconductors. Results for Si, change from 3.7 × 10 −6 K −1 for a bulk crystal down to a minimum value of 0.1 × 10 −6 K −1 for a 6 nm diameter nanoparticle.

  9. Models for mean bonding length, melting point and lattice thermal expansion of nanoparticle materials

    Energy Technology Data Exchange (ETDEWEB)

    Omar, M.S., E-mail: dr_m_s_omar@yahoo.com [Department of Physics, College of Science, University of Salahaddin-Erbil, Arbil, Kurdistan (Iraq)

    2012-11-15

    Graphical abstract: Three models are derived to explain the nanoparticles size dependence of mean bonding length, melting temperature and lattice thermal expansion applied on Sn, Si and Au. The following figures are shown as an example for Sn nanoparticles indicates hilly applicable models for nanoparticles radius larger than 3 nm. Highlights: ► A model for a size dependent mean bonding length is derived. ► The size dependent melting point of nanoparticles is modified. ► The bulk model for lattice thermal expansion is successfully used on nanoparticles. -- Abstract: A model, based on the ratio number of surface atoms to that of its internal, is derived to calculate the size dependence of lattice volume of nanoscaled materials. The model is applied to Si, Sn and Au nanoparticles. For Si, that the lattice volume is increases from 20 Å{sup 3} for bulk to 57 Å{sup 3} for a 2 nm size nanocrystals. A model, for calculating melting point of nanoscaled materials, is modified by considering the effect of lattice volume. A good approach of calculating size-dependent melting point begins from the bulk state down to about 2 nm diameter nanoparticle. Both values of lattice volume and melting point obtained for nanosized materials are used to calculate lattice thermal expansion by using a formula applicable for tetrahedral semiconductors. Results for Si, change from 3.7 × 10{sup −6} K{sup −1} for a bulk crystal down to a minimum value of 0.1 × 10{sup −6} K{sup −1} for a 6 nm diameter nanoparticle.

  10. Prediction and control of the coefficient of thermal expansion of concrete

    International Nuclear Information System (INIS)

    Ziegeldorf, S.; Kleiser, K.; Hilsdorf, H.K.

    1979-01-01

    Prediction and control of the coefficient of thermal expansion of concrete. In this report various procedures for the prediction of the coefficient of thermal expansion of concrete are summarized. The values predicted with these procedures are compared to experimental data. In the experimental investigation the coefficient of thermal expansion of various types of aggregates and types of concrete both in a dry and a moist state in the temperature range RT/180 0 C have been measured. The most significant result obtained is that for equal volume fractions the thermal properties of coarse aggregates have a more pronounced effect upon thermal expansion of concrete than those of fine aggregates. In the analysis an attempt has been made to estimate the thermal expansion of concrete from the properties of the concrete components by means of a finite element procedure. On the basis of the experimental data and of the analysis of internal temperature stresses in the concrete a simple relationship for the determination of the coefficient of thermal expansion of concrete has been deduced. In this relationship different thermal properties of coarse and fine aggregates may be taken into account. Compared to other methods this relationship yields, both for dry and for moist concrete, values which are in good agreement with the experimental data. (orig.) [de

  11. Experimental datasets on engineering properties of expansive soil treated with common salt

    Directory of Open Access Journals (Sweden)

    Taiwo O. Durotoye

    2018-06-01

    Full Text Available Construction of highway pavements or high rise structures over the expansive soils are always problematic due to failures of volume change or swelling characteristic experienced in the water permeability of the soil. The data in this article represented summary of (Durotoye et al., 2016; Durotoye, 2016 [1,2]. The data explored different percentages of sodium chloride as additive in stabilizing the engineering properties of expansive soil compared with other available stabilizer previously worked on. Experimental procedures carried out on expansive soil include: (Liquid limit, Plastic limit, Plasticity index, Shrinkage limit, Specific gravity Free swell index and Optimum water content to determine the swelling parameters and (maximum dry density, California bearing ratio and unconfined compressive strength to determine the strength parameters. The results of the experiment were presented in pie charts. Keywords: Common salt, Expansive soil, Experimental procedure, Strength parameters, Swelling parameters

  12. Robotlar İşlerimizi ve Ruhumuzu mu Çalacak?

    OpenAIRE

    Yılmaz, Fevzi

    2018-01-01

    Robotlar, bazen insan formunda bazen ise daha mekanik-elektronik araçlar olarak ekonomik hayatın içindeler. Dijital çağdayız ve robotlar artık kendilerine verilen yetkinlikler sayesinde insanların yapabildiği şeyleri gerçekleştirebiliyor. Robotların işsizliğe yol açacağı ve ekonomik eşitsizliği derinleştireceği sık sık gündeme gelmektedir. Bilim kurgu dizi konusu olan öldüren robotlar ve robotun kendini yapandan daha akıllı robotu üretmesi savı hep endişe vermiştir. Ünlülerden Stephen Hawking...

  13. Karayatak (Şabanözü güneyi) bentonitlerinin mineralojisi ve sedimantolojisi

    OpenAIRE

    DİKMEN, Asuman

    2009-01-01

    Çankırı civarında halen işletilmekte olan ve önemli rezerve sahip bentonit yatakları bulunmaktadır. Bu çalışma ile Şabanözü Karayatak Bentonit oluşumunun mineralojik ve sedimantolojik özelliklerinin incelenmesi ve kökeninin açıklanması amaçlanmıştır.İnceleme alanındaki Tersiyer istifi, Paleosen yaşlı granitoyid, Geç Miyosen yaşlı Karakocaş ve Mamak formasyonları ile Pliyosen yaşlı Bozdağ bazaltı ve Gölbaşı formasyonu olarak incelenmiştir. Şabanözü Karayatak bentonit oluşu...

  14. Changes in circulating blood volume after infusion of hydroxyethyl starch 6% in critically ill patients

    DEFF Research Database (Denmark)

    Christensen, P; Andersson, J; Rasmussen, S E

    2001-01-01

    The cardiovascular response to a volume challenge with hydroxyethyl starch (HES) (200/0.5) 6% depends on the relation between the volume of HES 6% infused and the expansion of the blood volume in critically ill patients. However, only relatively limited data exist on the plasma expanding effect...... of infusion of HES 6% in critically ill patients. The purpose of the study was to evaluate the variation in the expansion of the circulating blood volume (CBV) in critically ill patients after infusion of 500 ml of colloid (HES (200/0.5) 6%) using the carbon monoxide method....

  15. Estudo piloto com Eco 3D das modificações geométricas do VE após infarto do miocárdio

    Directory of Open Access Journals (Sweden)

    Marcelo Luiz Campos Vieira

    2013-07-01

    Full Text Available FUNDAMENTO: Remodelamento ventricular esquerdo (RVE após IAM caracteriza fator de mau prognóstico. Há pouca informação na literatura sobre o RVE analisado com ecocardiografia tridimensional (ECO 3D OBJETIVO: Analisar com ECO 3D as modificações geométricas e volumétricas do ventrículo esquerdo (VE seis meses após IAM em pacientes submetidos a tratamento primário percutâneo. MÉTODOS: Estudo prospectivo com ECO 3D de 21 indivíduos (16 homens, 56 ± 12 anos, acometidos por IAM com elevação do segmento ST. Foi feita a análise morfofuncional (VE com ECO 3D (volumes, FEVE, índice de esfericidade 3D até sete dias e seis meses após o IAM. RVE foi considerado para aumento > 15% do volume diastólico final do VE (VDFVE após seis meses do IAM, comparado ao VDFVE até sete dias do evento. RESULTADOS: Oito (38% pacientes apresentaram RVE. Medidas ecocardiográficas (n = 21 pacientes: I- até sete dias do IAM: 1- VDFVE: 92,3 ± 22,3 mL; 2- FEVE: 0,51 ± 0,01; 3- índice de esfericidade: 0,38 ± 0,05; II- após seis meses: 1- VDFVE: 107,3 ± 26,8 mL; 2- FEVE: 0,59 ± 0,01; 3- índice de esfericidade: 0,31 ± 0,05. Coeficiente de correlação (r entre índice de esfericidade até sete dias do IAM e VDFVE aos seis meses (n = 8 após o IAM: r: 0,74, p = 0,0007; (r entre índice de esfericidade após seis meses do IAM e VDFVE aos seis meses do IAM: r: 0,85, p < 0,0001. CONCLUSÃO: Nesta série, foi observado RVE em 38% dos pacientes seis meses após IAM. O índice de esfericidade tridimensional foi associado à ocorrência de RVE.

  16. Ankara Merkez İlçeleri ve Köylerinde Ev Konserveciliği Teknikleri ve Konservelerin Bazı Organoleptik ve Mikrobiyolojik Özellikleri

    Directory of Open Access Journals (Sweden)

    Necla Yazıcı

    2015-02-01

    Full Text Available Bu çalışmada, Ankara İlinin merkez ilçelerine bağlı köylerde yapılmakta olan ev konserveciliği uygulamalarına ait tekniklerin saptanması ve yapılan konservelerin organoleptik ve mikrobiyolojik analizlere dayanarak, bazı kalite özelliklerinin belirlenmesi amaçlanmıştır. Araştırmada Ankara İlinin merkez ilçelerine bağlı, 13 köyde, 154 deneğe anket uygulanmış ve ayrıca deneklerden toplanan 50 konserve örneği organoleptik ve mikrobiyolojik testlere tabi tutulmuştur. Araştırma bulgularına göre deneklerin %97.40’ı sebze konservesi kavanozlarını açık kazanda kaynatmaktadırlar. Deneklerin %48.00’i kavanozları boşluk bırakmadan, %30’u ise yarısına kadar doldurmaktadırlar. Kavanozların havasını alan deneklerin oranı %80.50’dir. Kaynatma işleminde süre tutan denekler %85.71 oranındadır. Bu deneklerin de %71.42’si kaynatma işlemi için yeterli süre uygulamaktadırlar. Konservelerde kaynatmadan sonra bozulma gören denekler %70.13, saklama sırasında bozulma görenler %40.91 oranındadır. Kaynatmadan sonra meydana gelen bozulmaların başında %73.14 oranı ile kapak atması gelmektedir. Toplam 50 konserve örneğinin organoleptik analizi sonucunda örneklerin %18’i renk, %30’u koku, %18’i genel görünüş bakımından kötü olarak değerlendirilmiştir. Mikrobiyolojik analizler sonucunda ise toplam 50 konserve örneğinin %20’sinde üreme görülmüştür. Alınan örneklerin, aerob koşullarda %14’ünde 35 oC de; %16’sında 55 oC’de; anaerob koşullarda ise %12’sinde 35 oC’de; %16’sında 55 oC’de üreme görülmüştür.

  17. Medicaid Expansion And Grant Funding Increases Helped Improve Community Health Center Capacity.

    Science.gov (United States)

    Han, Xinxin; Luo, Qian; Ku, Leighton

    2017-01-01

    Through the expansion of Medicaid eligibility and increases in core federal grant funding, the Affordable Care Act (ACA) sought to increase the capacity of community health centers to provide primary care to low-income populations. We examined the effects of the ACA Medicaid expansion and changes in federal grant levels on the centers' numbers of patients, percentages of patients by type of insurance, and numbers of visits from 2012 to 2015. In the period after expansion (2014-15), health centers in expansion states had a 5 percent higher total patient volume, larger shares of Medicaid patients, smaller shares of uninsured patients, and increases in overall visits and mental health visits, compared to centers in nonexpansion states. Increases in federal grant funding levels were associated with increases in numbers of patients and of overall, medical, and preventive service visits. If federal grant levels are not sustained after 2017, there could be marked reductions in health center capacity in both expansion and nonexpansion states. Project HOPE—The People-to-People Health Foundation, Inc.

  18. Thermal expansion behaviour of high performance PEEK matrix composites

    International Nuclear Information System (INIS)

    Goyal, R K; Mulik, U P; Tiwari, A N; Negi, Y S

    2008-01-01

    The thermal expansion behaviour of high performance poly(ether-ether-ketone) (PEEK) composites reinforced with micro- (8 μm) and nano- (39 nm) sized Al 2 O 3 particles was studied. The distribution of Al 2 O 3 in the PEEK matrix was studied by scanning electron microscopy and transmission electron microscopy. The coefficient of thermal expansion (CTE) was reduced from 58 x 10 -6 deg. C -1 for pure PEEK to 22 x 10 -6 deg. C -1 at 43 vol% micro-Al 2 O 3 and to 23 x 10 -6 deg. C -1 at 12 vol% nano-Al 2 O 3 composites. For a given volume fraction, nano-Al 2 O 3 particles are more effective in reducing the CTE of composites than that of micro-Al 2 O 3 particles. This may be attributed to the much higher interfacial area or volume of nanocomposites than that of microcomposites. The upper limit and lower limit of the Schapery model separately fit closely the CTE of the micro- and nano-composites, respectively. Other models such as the rule of mixture and Kerner and Turner models were also correlated with the data

  19. Thermal expansion of ThO2-2 wt% UO2 by HT-XRD

    International Nuclear Information System (INIS)

    Tyagi, A.K.; Mathews, M.D.

    2000-01-01

    The linear thermal expansion of polycrystalline ThO 2 -2 wt% UO 2 has been investigated from room temperature to 1473 K in flowing helium atmosphere using high temperature X-ray diffractometry. ThO 2 -2 wt% UO 2 shows a marginally higher linear thermal expansion as compared to pure ThO 2 . The average linear and volume thermal expansion coefficients of ThO 2 -2 wt% UO 2 are found to be α-bar a =9.74x10 -6 K -1 and α-bar v =29.52x10 -6 K -1 (298-1473 K). This study will be useful in designing the nuclear reactor fuel assembly based on ThO 2

  20. Turbulent forced convection of nanofluids downstream an abrupt expansion

    Science.gov (United States)

    Kimouche, Abdelali; Mataoui, Amina

    2018-03-01

    Turbulent forced convection of Nanofluids through an axisymmetric abrupt expansion is investigated numerically in the present study. The governing equations are solved by ANYS 14.0 CFD code based on the finite volume method by implementing the thermo-physical properties of each nanofluid. All results are analyzed through the evolutions of skin friction coefficient and Nusselt number. For each nanofluid, the effect of both volume fraction and Reynolds number on this type of flow configuration, are examined. An increase on average Nusselt number with the volume fraction and Reynolds number, are highlighted and correlated. Two relationships are proposed. The first one, determines the average Nusselt number versus Reynolds number, volume fraction and the ratio of densities of the solid particles to that of the base fluid ( \\overline{Nu}=f(\\operatorname{Re},φ, ρ_s/ρ_f) ). The second one varies according Reynolds number, volume fraction and the conductivities ratio of solid particle to that of the base fluid ( \\overline{Nu}=f(\\operatorname{Re},φ, k_s/k_f) ).

  1. Brain volume reductions in adolescent heavy drinkers.

    Science.gov (United States)

    Squeglia, Lindsay M; Rinker, Daniel A; Bartsch, Hauke; Castro, Norma; Chung, Yoonho; Dale, Anders M; Jernigan, Terry L; Tapert, Susan F

    2014-07-01

    Brain abnormalities in adolescent heavy drinkers may result from alcohol exposure, or stem from pre-existing neural features. This longitudinal morphometric study investigated 40 healthy adolescents, ages 12-17 at study entry, half of whom (n=20) initiated heavy drinking over the 3-year follow-up. Both assessments included high-resolution magnetic resonance imaging. FreeSurfer was used to segment brain volumes, which were measured longitudinally using the newly developed quantitative anatomic regional change analysis (QUARC) tool. At baseline, participants who later transitioned into heavy drinking showed smaller left cingulate, pars triangularis, and rostral anterior cingulate volume, and less right cerebellar white matter volumes (pteens. Over time, participants who initiated heavy drinking showed significantly greater volume reduction in the left ventral diencephalon, left inferior and middle temporal gyrus, and left caudate and brain stem, compared to substance-naïve youth (pbrain regions in future drinkers and greater brain volume reduction in subcortical and temporal regions after alcohol use was initiated. This is consistent with literature showing pre-existing cognitive deficits on tasks recruited by frontal regions, as well as post-drinking consequences on brain regions involved in language and spatial tasks. Published by Elsevier Ltd.

  2. Modern ve Postmodern Değerlerin Yabancılaşmaya Etkisi

    Directory of Open Access Journals (Sweden)

    Mahmut ŞAYLIKAY

    2016-08-01

    Full Text Available Bilindiği üzere, yabancılaşma, kişinin kendi benliğinden, çevresinden ve sosyalyaşamdan uzaklaşarak bu kavramların etkisi altına girmek olarak tanımlanabilir. Buyönüyle yabancılaşma, sendikalaşmaya hizmet etmesi açısından son derece önemlidir.Diğer taraftan modern ve post modern değerlerin sendikalaşmaya etkisi ise, bireyin belirlibir sendikayla özdeşleşmesi, sendikaya bağlılığı ve kendini adamasıdır. „‟Modernizationand postmodernization: Cultural, economic and political change in 43 societies„‟ adlıçalışmasıyla, Inglehart (1997, „‟Post modern Values in Seven Confucian Societies:Political Consequences of Changing World Views‟‟ adlı çalışmasıyla Wang(2007 ve ‘’Alienation and freedom: The factory worker and his industry.‟‟ adlı çalışmasıyla Blauner(1964 modern - post modern değerler ve yabancılaşma kavramlarına ilişkin literatüre katkısağlamışlardır. Bu çalışmada, sendika üyesi işçilere yönelik söz konusu değişkenlerarasındaki ilişki ve ilişkinin boyutu araştırılmaktadır. Çalışma sayesinde sendika üyelerininsahip oldukları modern ve post modern değerlerinin sosyal yaşama etkileri ve yabancılaşmaboyutlarına göstermiş olduğu tutum ve davranışlar ortaya koyularak sonuçlarıpaylaşılmıştır. Bu bağlamda, çalışmanın temel amacı, sendika üyeleri temelinde, ilişki veetkiler bakımından modern ve post modern değerlerin yabancılaşma ile ilişkisini ele alıp,sendika üyelerinin “yabancılaşma” davranışında bulunma algılarını yapılan araştırmabulgularıyla ortaya koymaktır. Araştırmada, birincil veri toplama yöntemlerinden yüz yüzeanket yöntemi gerçekleştirilmiş ve modern-post modern değerler için, Inglehart‟ın(1997,Fries ve arkadaşları (2007 ve Wang (2007 tarafından geliştirilen modernizm-postmodernizm ölçeği kullanılmıştır. Yabancılaşma ölçeği olarak Blauner‟s (1964 taraf

  3. Kazak Mitleri ve Mitik Efsaneleri Hakkında

    OpenAIRE

    İBRAYEV, Şakir; ARIKAN, Metin

    2006-01-01

    Kazak halkının geleneksel dünya görüşü ile söz sanatının kaynağı diyebileceğimiz mitler; dünyanın yaratılışı, nelerin, nasıl, nereden meydana çıktığı, sebebi ve safhaları, etrafımızı kuşatan çevrenin sırları ve özellikleri hakkında söylenen, insanoğlunun ilkel düşüncesinin sonucu meydana gelen olağanüstü anlatmalar, belki de inanışlar, anlayışlar. En eski mitlerin arasında gökyüzü cisimleri - güneş, ay, yıldız ve gezegenler hakkında söylenilen mitleri gösterebiliriz. Bu türdeki mitlerin başlı...

  4. VeLoc: Finding Your Car in Indoor Parking Structures.

    Science.gov (United States)

    Gao, Ruipeng; He, Fangpu; Li, Teng

    2018-05-02

    While WiFi-based indoor localization is attractive, there are many indoor places without WiFi coverage with a strong demand for localization capability. This paper describes a system and associated algorithms to address the indoor vehicle localization problem without the installation of additional infrastructure. In this paper, we propose VeLoc, which utilizes the sensor data of smartphones in the vehicle together with the floor map of the parking structure to track the vehicle in real time. VeLoc simultaneously harnesses constraints imposed by the map and environment sensing. All these cues are codified into a novel augmented particle filtering framework to estimate the position of the vehicle. Experimental results show that VeLoc performs well when even the initial position and the initial heading direction of the vehicle are completely unknown.

  5. Elektrikli Otomobil, Küresel Rekabet ve Gelişmeler

    OpenAIRE

    Yılmaz, Fevzi

    2017-01-01

    Önceki Bilim, Sanayi ve Teknoloji Bakanı Fikri Işık Mayıs 2016'da verdiği beyanatta yerli otomobil projesiyle Google ve Tesla gibi devlerin rakibi olacağımızı belirtmişti. Bakan Işık o tarihte, “Tüm otomotiv devleri, işbirliği için sırada bekliyor. Sonuçta bizim de elimizde önemli teknolojiler var.” diyerek moral tazelemişti. Sözü edilen Google, araç otomasyonu ve sürücüsüz araç projesi yürütmekte iken, Tesla ise dünyanın en büyük farklı konsept elektrikli araç üreticisidir. Tesla'nın CEO’su ...

  6. PERİFERİK KAN KÜLTÜRÜ VE YÖNETİMİ

    OpenAIRE

    ARDAHAN SEVGİLİ, SEDA; YARDIMCI, FİGEN

    2018-01-01

    Başlık: PERİFERİK KAN KÜLTÜRÜ VE YÖNETİMİTitle: PERIPHERALBLOOD CULTURE AND MANAGEMENTÖzet: Kandolaşımı enfeksiyonları; enfeksiyona neden olan mikroorganizma ile etkilediğicanlı arasında birçok etkileşim sonucunda meydana gelen ve oldukça karmaşık birsüreçtir. Bundan dolayı kan dolaşımı enfeksiyonlarının erken dönemdetanılanması ve tanısına yönelik tedavisinin başlatılması yaşamsal önemtaşımaktadır. Kan kültürleri; ciddi kan dolaşımı enfeksiyonlarının tanımlanmasıve...

  7. Slow Learner Prediction Using Multi-Variate Naïve Bayes Classification Algorithm

    Directory of Open Access Journals (Sweden)

    Shiwani Rana

    2017-01-01

    Full Text Available Machine Learning is a field of computer science that learns from data by studying algorithms and their constructions. In machine learning, for specific inputs, algorithms help to make predictions. Classification is a supervised learning approach, which maps a data item into predefined classes. For predicting slow learners in an institute, a modified Naïve Bayes algorithm implemented. The implementation is carried sing Python.  It takes into account a combination of likewise multi-valued attributes. A dataset of the 60 students of BE (Information Technology Third Semester for the subject of Digital Electronics of University Institute of Engineering and Technology (UIET, Panjab University (PU, Chandigarh, India is taken to carry out the simulations. The analysis is done by choosing most significant forty-eight attributes. The experimental results have shown that the modified Naïve Bayes model has outperformed the Naïve Bayes Classifier in accuracy but requires significant improvement in the terms of elapsed time. By using Modified Naïve Bayes approach, the accuracy is found out to be 71.66% whereas it is calculated 66.66% using existing Naïve Bayes model. Further, a comparison is drawn by using WEKA tool. Here, an accuracy of Naïve Bayes is obtained as 58.33 %.

  8. Prehransko opismenjevanje otrok z vidika usvajanja prehranskih veščin

    OpenAIRE

    Kostanjevec, Stojan; Erjavšek, Martina

    2017-01-01

    Na zdravje in kakovost življenja posameznika vpliva stopnja njegove prehranske pismenosti, katere pomemben del so tudi usvojene prehranske veščine in od katerih je odvisen izbor hrane, ki jo posameznik pripravlja in uživa. Prehransko vešč posameznik je zmožen uporabiti usvojeno prehransko znanje pri načrtovanju prehrane, nakupovanju živil in pri pripravi obrokov hrane. Namen raziskave je bil ugotoviti, katere prehranske veščine usvojijo osnovnošolci v šolskem in domačem okolju ter kako pogost...

  9. Melatonin ve Bağışıklık Sistemi

    OpenAIRE

    ÇETİN, E.

    2005-01-01

    Melatonin, pineal bezin beta adrenerjik reseptörlerinin aktivasyonu ile triptofandan sentezlenen bir hormondur.Üretim ve salınımı karanlık ile başlar ve aydınlıkla sona erer. Melatonin, birçok biyolojik fonksiyonun düzenlenmesinderol oynar. Bu derlemede melatonin hakkında genel bilgiler verilerek, melatoninin lenfoid dokular, humoral bağışıklık,hücresel bağışıklık ve kanser üzerine etkileri tartışılmıştır

  10. FEKAL İNKONTİNANSIN BAKIMI VE BAKIMDA KULLANILAN ÜRÜNLER

    OpenAIRE

    Denat, Yıldız; Khorshid, Leyla

    2010-01-01

    ÖZETFekal inkontinans, özellikle uzun dönem yatağa bağımlı hastalarda kontaminasyonaçısından güç sonuçlarla, enfeksiyon ve deri ülserlerinin oluşma riskiyle, pahalı ve potansiyeltehlikelere neden olan bir durumdur. Fekal inkontinans, normal deri bütünlüğü için potansiyel birtehlike yaratır ve septiseminin bir nedeni olabilir. Özellikle yatağa bağımlı fekal inkontinanslıhastalar perineal deri hasarı için risk ...

  11. Servikal nöral foraminal bölge ve uncinate çıkıntının embriolojik gelişimi ve anatomisinin klinikle ilişkilendirilmesi

    OpenAIRE

    BROHİ, Recep Ali

    2012-01-01

    Servikal bölge ile ilgili yapılan anatomik ve morfometrik çalışmaların büyük çoğunluğunda erişkin kadavra ve kemikleri kullanılmıştır. Servikal bölgenin ve bu bölge ile patolojilerde önemli rol oynayan uncinate proses ve servikal nöral foramen ile ilgili çalışmalar literatürde bulunsa da bu iki yapının embriolojik gelişimi yeterin...

  12. DOMATES DOKU VE KÜF KARAKTERİSTİKLERİ, DOMATES ÜRÜNLERİNDE KÜF SAYIMI VE KÜFÜ AZALTMA OLANAKLARI

    Directory of Open Access Journals (Sweden)

    Çetin KADAKAL

    2001-02-01

    Full Text Available Domates ve ürünlerinde en önemli kalite kriterlerinden biri, ürünün küf yüküdür. Domates ve ürünlerinde küf yükü; Howard küf sayım (HMC metoduna göre yapılmaktadır. Küf yükü, son ürünün hijyenik koşullarda üretilip üretilmediğini göstermesi açısından önemlidir. Küf yükünün maksimum sınırı ülkeden ülkeye değişmekle birlikte % 40-60 (pozitif alan arasındadır. Son yıllarda domates ve ürünlerinde ergosterol düzeyi küf yükü yerine yeni bir kriter olarak kabul edilmeye başlanmıştır.

  13. Volume changes in unrestrained structural lightweight concrete.

    Science.gov (United States)

    1964-08-01

    In this study a comparator-type measuring system was developed to accurately determine volume change characteristics of one structural lightweight concrete. The specific properties studied were the coefficient of linear thermal expansion and unrestra...

  14. In2Mo3O12: A low negative thermal expansion compound

    International Nuclear Information System (INIS)

    Marinkovic, Bojan A.; Ari, Monica; Jardim, Paula Mendes; Avillez, Roberto R. de; Rizzo, Fernando; Ferreira, Fabio Furlan

    2010-01-01

    Orthorhombic In 2 Mo 3 O 12 has low negative linear coefficient of thermal expansion (α l = -1.85 x 10 -6 o C -1 ) as evaluated by X-ray powder diffraction using a synchrotron facility. The linear coefficient of thermal expansion for orthorhombic In 2 Mo 3 O 12 is directly dependent on the inherent volume distortion parameter (υ) of InO 6 . This finding strongly corroborates the recently proposed relationship between the linear coefficient of thermal expansion in A 2 M 3 O 12 compounds (α l ) and the distortion level of AO 6 polyhedra. With the increase of inherent distortion parameter (υ) of AO 6 polyhedra, the linear coefficient of thermal expansion becomes more negative. Another important feature of AO 6 polyhedra, including InO 6 , is that their distortion increases as a function of temperature. Orthorhombic In 2 Mo 3 O 12 is stable in the studied temperature range, 370-760 o C.

  15. The CEVALE2VE case

    CERN Document Server

    AUTHOR|(INSPIRE)INSPIRE-00237353; The ATLAS collaboration

    2017-01-01

    A virtual research and learning community can be a powerful tool for educational purposes. It has a wide range of possibilities for multi-institution participation, such as synchronous and asynchronous online engagement, decentralized student discussions and academic networking - as well as being cost effective. In this context, the CEVALE2VE virtual community (Centro de Altos Estudios de Altas Energías) is a Venezuelan initiative to support the new generation of researchers in High Energy Physics (HEP). Its goal is to contribute to the scientific dissemination of fundamental physics and the regional modernization of university education. The members of CEVALE2VE are a group of Venezuelan researchers, currently involved in projects related to the HEP field, and geographically located in different academic institutions of Europe and North America. The project involves several academic institutions in Venezuela and Colombia in order to reach a wide audience, and exploits current communications technologies, w...

  16. The CEVALE2VE case

    CERN Document Server

    Sanchez Pineda, Arturo; The ATLAS collaboration

    2016-01-01

    A virtual research and learning community can be a powerful tool for educational purposes. It has a wide range of possibilities for multi-institution participation, such as synchronous and asynchronous online engagement, decentralized student discussions and academic networking - as well as being cost effective. In this context, the CEVALE2VE virtual community (Centro de Altos Estudios de Altas Energías) is a Venezuelan initiative to support the new generation of researchers in high energy physics (HEP). Its goal is to contribute to the scientific dissemination of fundamental physics and the regional modernization of university education. The members of CEVALE2VE are a group of Venezuelan researchers, currently involved in projects related to the HEP field, and geographically located in different academic institutions of Europe and North America. The project involves several academic institutions in Venezuela and Colombia in order to reach a wide audience, and exploits current communications technologies, wh...

  17. Using VE to Strategically Plan Our Future

    Energy Technology Data Exchange (ETDEWEB)

    Margie Jeffs; Lori Braase; Alison Conner; Darcie Martinson; Jodi Grgich

    2009-06-01

    The Value Engineering (VE) Methodology is an effective tool for business or project strategic planning. In conjunction with the “Balanced Scorecard Approach” (Drs. Robert Kaplan, PhD, and David Norton, PhD, from the Balanced Scorecard Collaborative/Palladium Group), function analysis can be used to develop strategy maps and scorecards. The FAST diagram provides an integrated approach to strategy map development by formulating a cause and effect relationship and establishing the “how” and “why” behind the strategy map. By utilizing the VE Job Plan, one is able to move from strategic thinking all the way through to execution of the strategy.

  18. Modeling Lake Storage Dynamics to support Arctic Boreal Vulnerability Experiment (ABoVE)

    Science.gov (United States)

    Vimal, S.; Lettenmaier, D. P.; Smith, L. C.; Smith, S.; Bowling, L. C.; Pavelsky, T.

    2017-12-01

    The Arctic and Boreal Zone (ABZ) of Canada and Alaska includes vast areas of permafrost, lakes, and wetlands. Permafrost thawing in this area is expected to increase due to the projected rise of temperature caused by climate change. Over the long term, this may reduce overall surface water area, but in the near-term, the opposite is being observed, with rising paludification (lake/wetland expansion). One element of NASA's ABoVE field experiment is observations of lake and wetland extent and surface elevations using NASA's AirSWOT airborne interferometric radar, accompanied by a high-resolution camera. One use of the WSE retrievals will be to constrain model estimates of lake storage dynamics. Here, we compare predictions using the lake dynamics algorithm within the Variable Infiltration Capacity (VIC) land surface scheme. The VIC lake algorithm includes representation of sub-grid topography, where the depth and area of seasonally-flooded areas are modeled as a function of topographic wetness index, basin area, and slope. The topography data used is from a new global digital elevation model, MERIT-DEM. We initially set up VIC at sites with varying permafrost conditions (i.e., no permafrost, discontinuous, continuous) in Saskatoon and Yellowknife, Canada, and Toolik Lake, Alaska. We constrained the uncalibrated model with the WSE at the time of the first ABoVE flight, and quantified the model's ability to predict WSE and ΔWSE during the time of the second flight. Finally, we evaluated the sensitivity of the VIC-lakes model and compared the three permafrost conditions. Our results quantify the sensitivity of surface water to permafrost state across the target sites. Furthermore, our evaluation of the lake modeling framework contributes to the modeling and mapping framework for lake and reservoir storage change evaluation globally as part of the SWOT mission, planned for launch in 2021.

  19. Japon Balığı (Carassius Auratus L. 1758) ve Arpa Bitkisinin (Hordeum Vulgare L.) Gelişimi ve Su Kalitesinin İyileştirilmesi Üzerine Aquaponik Sistemin Etkileri

    OpenAIRE

    KESKİNBALTA, Mehmet Anıl; HAMZAOĞLU, Gökhan; ÇELİK, Meryem Yeşim; DERNEKBAŞI, Seval

    2015-01-01

    Bu araştırmada, Japon balığı (Carassius auratus L. 1758) ve arpa bitkisi (Hordeum vulgare L.) kullanılarak model bir akuaponik sistem oluşturulmuştur. Araştırma süresince arpa bitkisinin suyun nitrit, nitrat ve fosfat değerlerinde yaptığı değişim ve balıkların gelişimi üzerindeki etkilerinin belirlenmesi amaçlanmıştır. 30 günlük araştırma süresince günlük olarak pH, sıcaklık ve oksijen değerleri ölçülmüştür. Haftalık olarak bitki yetiştirme yatağına giren ve bitkiden süzülen suyun nitrit (NO2...

  20. Japon Balığı (Carassius auratus L. 1758) ve Arpa Bitkisinin (Hordeum vulgare L.) Gelişimi ve Su Kalitesinin İyileştirilmesi Üzerine Aquaponik Sistemin Etkileri

    OpenAIRE

    KESKİNBALTA, Mehmet; HAMZAOĞLU, Gökhan; ÇELİK, Meryem; DERNEKBAŞI, Seval

    2015-01-01

    Bu araştırmada, Japon balığı (Carassius auratus L. 1758) ve arpa bitkisi (Hordeum vulgare L.) kullanılarak model bir akuaponik sistem oluşturulmuştur. Araştırma süresince arpa bitkisinin suyun nitrit, nitrat ve fosfat değerlerinde yaptığı değişim ve balıkların gelişimi üzerindeki etkilerinin belirlenmesi amaçlanmıştır. 30 günlük araştırma süresince günlük olarak pH, sıcaklık ve oksijen değerleri ölçülmüştür. Haftalık olarak bitki yetiştirme yatağına giren ve bitkiden süzülen suyun nitrit (NO2...

    1. Defense.gov Special Report: V-E Day - 70th Anniversary

      Science.gov (United States)

      are strong united we will win WWII United Nations4 United We Win WWII United We can't win without them Historic Aircraft to Conduct V-E Day Flyover America will remember the millions who helped make possible 70th Anniversary in France Arsenal of Democracy Flyover Media Day V-E Day Veterans Profiles Charles

    2. Clinical response to eliglustat in treatment-naïve patients with Gaucher disease type 1: Post-hoc comparison to imiglucerase-treated patients enrolled in the International Collaborative Gaucher Group Gaucher Registry

      Directory of Open Access Journals (Sweden)

      Jennifer Ibrahim

      2016-09-01

      Full Text Available Eliglustat is a recently approved oral therapy in the United States and Europe for adults with Gaucher disease type 1 who are CYP2D6 extensive, intermediate, or poor metabolizers (>90% of patients that has been shown to decrease spleen and liver volume and increase hemoglobin concentrations and platelet counts in untreated adults with Gaucher disease type 1 and maintain these parameters in patients previously stabilized on enzyme replacement therapy. In a post-hoc analysis, we compared the results of eliglustat treatment in treatment-naïve patients in two clinical studies with the results of imiglucerase treatment among a cohort of treatment-naïve patients with comparable baseline hematologic and visceral parameters in the International Collaborative Gaucher Group Gaucher Registry. Organ volumes and hematologic parameters improved from baseline in both treatment groups, with a time course and degree of improvement in eliglustat-treated patients similar to imiglucerase-treated patients.

    3. Clinical response to eliglustat in treatment-naïve patients with Gaucher disease type 1: Post-hoc comparison to imiglucerase-treated patients enrolled in the International Collaborative Gaucher Group Gaucher Registry.

      Science.gov (United States)

      Ibrahim, Jennifer; Underhill, Lisa H; Taylor, John S; Angell, Jennifer; Peterschmitt, M Judith

      2016-09-01

      Eliglustat is a recently approved oral therapy in the United States and Europe for adults with Gaucher disease type 1 who are CYP2D6 extensive, intermediate, or poor metabolizers (> 90% of patients) that has been shown to decrease spleen and liver volume and increase hemoglobin concentrations and platelet counts in untreated adults with Gaucher disease type 1 and maintain these parameters in patients previously stabilized on enzyme replacement therapy. In a post-hoc analysis, we compared the results of eliglustat treatment in treatment-naïve patients in two clinical studies with the results of imiglucerase treatment among a cohort of treatment-naïve patients with comparable baseline hematologic and visceral parameters in the International Collaborative Gaucher Group Gaucher Registry. Organ volumes and hematologic parameters improved from baseline in both treatment groups, with a time course and degree of improvement in eliglustat-treated patients similar to imiglucerase-treated patients.

    4. A simple reactivity feedback model accounting for radial core expansion effects in the liquid metal fast reactor

      International Nuclear Information System (INIS)

      Kwon, Young Min; Lee, Yong Bum; Chang, Won Pyo; Haha, Do Hee

      2002-01-01

      The radial core expansion due to the structure temperature rise is one of major negative reactivity insertion mechanisms in metallic fueled reactor. Thermal expansion is a result of both the laws of nature and the particular core design and it causes negative reactivity feedback by the combination of increased core volume captures and increased core surface leakage. The simple radial core expansion reactivity feedback model developed for the SSC-K code was evaluated by the code-to-code comparison analysis. From the comparison results, it can be stated that the radial core expansion reactivity feedback model employed into the SSC-K code may be reasonably accurate in the UTOP analysis

    5. A simple reactivity feedback model accounting for radial core expansion effects in the liquid metal fast reactor

      Energy Technology Data Exchange (ETDEWEB)

      Kwon, Young Min; Lee, Yong Bum; Chang, Won Pyo; Haha, Do Hee [KAERI, Taejon (Korea, Republic of)

      2002-10-01

      The radial core expansion due to the structure temperature rise is one of major negative reactivity insertion mechanisms in metallic fueled reactor. Thermal expansion is a result of both the laws of nature and the particular core design and it causes negative reactivity feedback by the combination of increased core volume captures and increased core surface leakage. The simple radial core expansion reactivity feedback model developed for the SSC-K code was evaluated by the code-to-code comparison analysis. From the comparison results, it can be stated that the radial core expansion reactivity feedback model employed into the SSC-K code may be reasonably accurate in the UTOP analysis.

    6. Van’da Tüketime Sunulan Feta Peynirlerinin Mikrobiyolojik ve Kimyasal Kalitesi

      Directory of Open Access Journals (Sweden)

      Enise Akel

      2016-11-01

      Full Text Available Bu çalışma, Van il merkezinde tüketime sunulan Feta peynirlerinin mikrobiyolojik ve kimyasal kalitesini belirlemek amacıyla yapıldı. Çalışmada 50 adet Feta peyniri materyal olarak kullanıldı. Feta peynirlerinin mikrobiyolojik analizleri sonucunda, ortalama olarak toplam aerob mezofil genel canlı sayısı 5,49 log kob/g, laktik asit bakteri sayısı 5,20 log kob/g, koliform grubu mikroorganizma sayısı 0,78 log kob/g, Escherichia coli sayısı 0,10 log kob/g, mikrokok/stafilokok sayısı 0,58 log kob/g, koagülaz pozitif Staphylococcus aureus sayısı 0,53 log kob/g, Clostridium perfringens sayısı 0,08 log kob/g, enterobakteri sayısı 0,96 log kob/g, maya ve küf sayısı ise 5,18 log kob/g olarak saptandı. Kimyasal analizler sonucunda ise ortalama pH değeri 4,38, titre edilebilir asitlik derecesi %1,41 LA, kuru madde miktarı %41,21, yağ miktarı %18,12, kuru maddede yağ miktarı %44,18, tuz miktarı %8,36 ve kuru maddede tuz miktarı %20,42 olarak tespit edildi. Feta peyniri örneklerinin tamamı titre edilebilir asitlik yönünden standartlara uygun bulundu. Ancak örneklerin %8’i koagülaz pozitif S. aureus, %52’si pH ve %100’ü kuru maddede tuz yönünden standartlara uygun bulunmadı. Sonuç olarak, Feta peynirlerinin mikrobiyolojik ve kimyasal kalitesinin yetersiz olduğu ve bu durumun üretici ve tüketiciler için risk oluşturabileceği kanısına varıldı. Gıda zincirinin tüm aşamalarında temeli GMP olan HACCP sisteminin uygulanması gıda güvenliği, halk sağlığı ve tüketici haklarının korunmasında etkin rol oynayacaktır.

    7. Orta Asya ve Kafkasya’da Nükleer Enerji Açısından Türkiye’nin Mali Beklenti ve Riskleri: Praksiyolojik Bir İnceleme

      OpenAIRE

      Bahçe, Abdullah; Gümüş, Öner

      2016-01-01

       ÖzNükleer enerji birçok ülkenin birbirine karşı üstünlük sağlamada kullanabildikleri bir araçtır. Bunun temel sebebi de nükleer enerjinin ekonomik ve mali getiri sağlayarak ülkelerin kalkınmalarını etkileyebilecek bir potansiyele sahip olmasıdır. Bu yönüyle nükleer enerji, verginin doğmasına neden olacak bir etkiye de sahiptir. Türkiye’de ise nükleer enerji üretilememektedir. Bununla birlikte diğer enerji çeşitlerinin üretimi söz konusudur ve bu enerji çeşitlerinden üretilen mal ve hizmetler...

    8. Tiyatro, karikatür ve film provokasyonları bağlamında Fransız basınında İslam ve Hz. Muhammed imajı

      OpenAIRE

      METİN, İsmail

      2016-01-01

      Oryantalizm ve oryantalistler, tarih boyunca İslamı kendi zihin dünyasına göre anlamış ve bu yönde çalışmalar yapmıştır. Yapılan bu çalışmalar ilmi eserler, ansiklopediler, kitaplar, makaleler başta olmak üzere, yazılı ve görsel basında da yer almıştır. Bu makale, oryantalizmin önemli merkezlerinden olan Fransada, özellikle yazılı basında, başta İslam, Kuran-ı Kerim, Hz. Muhammed olmak üzere dini değerlerin medya tarafından algılanış biçimini, karikatür ve film provokasyonları bağlamında tari...

    9. NEVRUZ VE SUMER BEREKET KÜLTÜ AYNI KAYNAK DEĞİL Mİ?

      OpenAIRE

      ÇIĞ, Muazzez İlmiye

      2016-01-01

      Sumerliler insanlık tarihinin en eski kavimleri arasında yer almaktadır. Başta “yazı” olmak üzere kültür ve uygarlık simgesi birçok buluşun da Sumerlilere ait olduğu bilinmektedir. Türkler de tıpkı Sumerliler gibi insanlık tarihinin en eski kavimleri arasında yer almaktadır. Bu durum beraberinde “Peki Sumerliler ve Türkler arasında bir bağ var mıdır?” sorusunu akla getirmektedir. Başta Sumer belgeleri olmak üzere birçok bilgi ve belge Sumerliler ve Türkler arasında yakın bir...

    10. Stopping, heating, thermalization and expansion at SPS energies

      CERN Document Server

      Gaardhoje, J J

      1997-01-01

      The Pb beam at 158AGeV from the CERN SPS accelerator which was taken into use in the fall of 1994 has opened a new dimension in the study of highly excited nuclear matter in heavy ion reactions. It has now become possible to form reasonably large volumes (containing more than 300 nucleons) in central collisions between heavy ions, with energy and matter densities in some parts of the volume exceeding those expected for the phase transition from hadronic matter to deconfined quark and gluon matter. In this talk we discuss some features of the expansion of the hot and compressed system that may be learned by analysing the single particle spectra of baryons and mesons with emphasis on data from the NA44 experiment.

    11. Damla Sulama Koşullarında Aşılı ve Aşısız Karpuzlarda Bitki, Su ve Verim İlişkilerinin İrdelenmesi

      Directory of Open Access Journals (Sweden)

      Selçuk ÖZMEN

      2014-09-01

      Full Text Available Bu çalışma, 2006-2008 yılları arasında Çukurova Üniversitesi, Ziraat Fakültesi, Tarımsal Yapılar ve Sulama Bölümü deneme alanında yürütülmüştür. Araştırmada, damla sulama koşullarında aşılı ve aşısız karpuzlarda bitki, su ve verim ilişkileri irdelenmiştir. Denemede; tam sulanan aşılı (Crimson Tide+Jumbo:CTJ ve aşısız (Crimson Tide: CT konuları ele alınmıştır. Sulama suyu, sulama aralıkları arasında oluşan toplam A Sınıfı buharlaşma kabından okunan değerlere göre hesaplanmıştır. Çalışmada, konulara göre, sulama suyu (IW ve bitki su tüketimleri (ET, sırasıyla, 266.2–413.5 mm (12–16 sulama ve 433.1-520.6 mm arasında değişmiş; en yüksek IW ve mevsimlik ET ise, sırasıyla, 413.5 mm ve 520.6 mm ile CTJ konusundan 2006 yılında elde edilmiştir. Karpuz bitkisinde en yüksek ortalama aylık ET, 214.0 mm ile CTJ konusunda Mayıs ayında ölçülmüş; bu ayda ortalama çim kıyas bitki su tüketimi (ETo, 163.1 mm olarak belirlenmiştir. Bitki katsayısı (Kc değerlerinin; deneme yılları için, başlangıç, mevsim ortası ve mevsim sonudönemlerinde, sırasıyla, 0.240.67, 0.87-1.66 ve 0.83-0.93 olarak değiştiği saptanmıştır. Son yılki çalışmada; toplam kök yoğunluğunun aşılı konularda aşısızlara kıyasla % 4 daha fazla; yaprak su potansiyeli (YSP değerlerlerinin -0.20 ile -0.70 MPa arasında değiştiği ve aşılı konuların daha yüksek YSP değerlerine sahip olduğu saptanmıştır. Aşılama ile verim, toplam su kullanma randımanı (TWUE ve su kullanım randımanı (IWUE artarken sulama suyunun ET içerisindeki kullanım oranı (IWc aşısız konularında daha yüksek olduğu belirlenmiştir. En yüksek verim 712.8 kg/ha ile CTJ konusundan 2008 yılından elde edilmiştir

    12. Immediate impact of rapid maxillary expansion on upper airway dimensions and on the quality of life of mouth breathers

      Directory of Open Access Journals (Sweden)

      Edna Namiko Izuka

      2015-06-01

      Full Text Available OBJECTIVE: To assess short-term tomographic changes in the upper airway dimensions and quality of life of mouth breathers after rapid maxillary expansion (RME. METHODS: A total of 25 mouth breathers with maxillary atresia and a mean age of 10.5 years old were assessed by means of cone-beam computed tomography (CBCT and a standardized quality of life questionnaire answered by patients' parents/legal guardians before and immediately after rapid maxillary expansion. RESULTS: Rapid maxillary expansion resulted in similar and significant expansion in the width of anterior (2.8 mm, p < 0.001 and posterior nasal floor (2.8 mm, p < 0.001. Although nasopharynx and nasal cavities airway volumes significantly increased (+1646.1 mm3, p < 0.001, oropharynx volume increase was not statistically significant (+1450.6 mm3, p = 0.066. The results of the quality of life questionnaire indicated that soon after rapid maxillary expansion, patients' respiratory symptoms significantly decreased in relation to their initial respiratory conditions. CONCLUSIONS: It is suggested that RME produces significant dimensional increase in the nasal cavity and nasopharynx. Additionally, it also positively impacts the quality of life of mouth-breathing patients with maxillary atresia.

    13. Experimental datasets on engineering properties of expansive soil treated with common salt.

      Science.gov (United States)

      Durotoye, Taiwo O; Akinmusuru, Joseph O; Ogundipe, Kunle E

      2018-06-01

      Construction of highway pavements or high rise structures over the expansive soils are always problematic due to failures of volume change or swelling characteristic experienced in the water permeability of the soil. The data in this article represented summary of (Durotoye et al., 2016; Durotoye, 2016) [1], [2]. The data explored different percentages of sodium chloride as additive in stabilizing the engineering properties of expansive soil compared with other available stabilizer previously worked on. Experimental procedures carried out on expansive soil include: (Liquid limit, Plastic limit, Plasticity index, Shrinkage limit, Specific gravity Free swell index and Optimum water content) to determine the swelling parameters and (maximum dry density, California bearing ratio and unconfined compressive strength) to determine the strength parameters. The results of the experiment were presented in pie charts.

    14. Pressure-induced reversal between thermal contraction and expansion in ferroelectric PbTiO3.

      Science.gov (United States)

      Zhu, Jinlong; Zhang, Jianzhong; Xu, Hongwu; Vogel, Sven C; Jin, Changqing; Frantti, Johannes; Zhao, Yusheng

      2014-01-15

      Materials with zero/near zero thermal expansion coefficients are technologically important for applications in thermal management and engineering. To date, this class of materials can only be produced by chemical routes, either by changing chemical compositions or by composting materials with positive and negative thermal expansion. Here, we report for the first time a physical route to achieve near zero thermal expansion through application of pressure. In the stability field of tetragonal PbTiO3 we observed pressure-induced reversals between thermal contraction and expansion between ambient pressure and 0.9 GPa. This hybrid behavior leads to a mathematically infinite number of crossover points in the pressure-volume-temperature space and near-zero thermal expansion coefficients comparable to or even smaller than those attained by chemical routes. The observed pressures for this unusual phenomenon are within a small range of 0.1-0.9 GPa, potentially feasible for designing stress-engineered materials, such as thin films and nano-crystals, for thermal management applications.

    15. YAZILIM TEKRAR KULLANIMI VE NESNEYE YÖNELİK YAKLAŞIM

      Directory of Open Access Journals (Sweden)

      Halil ŞENGONCA

      1995-02-01

      Full Text Available Yazılımın tekrar kullanımı, bir yazılım sisteminin geliştirilmesinde kullanılan bilginin ve ürünlerin, başka bir yazılım sistemi için kullanılmasıdır. Yazılımın tekrar kullanımı için kaynak kod bileşenlerinden oluşan bir kütüphane ve karmaşık sistemlerin bu yapı bloklarından oluşturulması fikri, ilk olarak 1968'te Dough McIlroy tarafından önerilmiştir. Günümüzde programlama dilleri, kullanılan teknikler ve araçlar çok değişmesine rağmen yazılımın tekrar kullanımı yazılım geliştirme maliyetlerini azaltmak ve kaliteyi yükseltmek için hala bir çözüm olarak görülmektedir. Nesneye yönelik programlama, kalıtım, koruma gibi özellikleriyle, kaynak kod bileşenlerinin oluşturulmasını ve kullanımını desteklemektedir. Yine de yazılım tekrar kullanımını bir kuruluş düzeyinde gerçekleştirmek için planlı ve koordineli bir programa gereksinim vardır. Bu makalede, yazılım tekrar kullanımı tanımlanmış ve nesneye yönelik yaklaşım ile yazılım tekrar kullanımını amaçlayan bir yazılım geliştirme süreci tanıtılmıştır. Ayrıca bir kuruluşun yazılım tekrar kullanımını kurumsallaştırma süreci için bir strateji önerilmiştir.

    16. VeLoc: Finding Your Car in Indoor Parking Structures

      Directory of Open Access Journals (Sweden)

      Ruipeng Gao

      2018-05-01

      Full Text Available While WiFi-based indoor localization is attractive, there are many indoor places without WiFi coverage with a strong demand for localization capability. This paper describes a system and associated algorithms to address the indoor vehicle localization problem without the installation of additional infrastructure. In this paper, we propose VeLoc, which utilizes the sensor data of smartphones in the vehicle together with the floor map of the parking structure to track the vehicle in real time. VeLoc simultaneously harnesses constraints imposed by the map and environment sensing. All these cues are codified into a novel augmented particle filtering framework to estimate the position of the vehicle. Experimental results show that VeLoc performs well when even the initial position and the initial heading direction of the vehicle are completely unknown.

    17. Increased pulmonary vascular permeability as a cause of re-expansion edema in rabbits

      International Nuclear Information System (INIS)

      Pavlin, D.J.; Nessly, M.L.; Cheney, F.W.

      1981-01-01

      In order to study the mechanism(s) underlying re-expansion edema, we measured the concentration of labeled albumin (RISA) in the extravascular, extracellular water (EVECW) of the lung as a measure of pulmonary vascular permeability. Re-expansion edema was first induced by rapid re-expansion of rabbit lungs that had been collapsed for 1 wk by pneumothorax. The RISA in EVECW was expressed as a fraction of its plasma concentration: (RISA)L/(RISA)PL. The volume of EVECW (ml/gm dry lung) was measured using a 24 Na indicator. Results in re-expansion edema were compared with normal control lungs and with oleic acid edema as a model of permeability edema. In re-expanded lungs, EVECW (3.41 +/- SD 1.24 ml/g) and (RISA)L/(RISA)PL 0.84 +/- SD 0.15) were significantly increased when compared with normal control lungs (2.25 +/- 0.41 ml/g and 0.51 +/- 0.20, respectively). Results in oleic acid edema (5.66 +/- 2.23 ml/g and 0.84 +/- 0.23) were similar to re-expansion edema. This suggested that re-expansion edema is due to increased pulmonary vascular permeability caused by mechanical stresses applied to the lung during re-expansion

    18. FINDIK KABUKLARININ, ÇAY VE TÜTÜN ATIKLARININ HAMMADDE OLARAK KULLANILMASI

      Directory of Open Access Journals (Sweden)

      Ş. İsmail KIRBAŞLAR

      2001-01-01

      Full Text Available Bu çalışmada, fındık kabukları, çay ve tütün atıklarındaki nem, kül, yağ ve sellüloz miktarları analiz edilmiştir. Ayrıca, fındık kabukları, çay ve tütün atıklarının içerdiği pentosan, pentos ve furfural miktarları belirlenmiştir. Furfural her üç atıktan destilasyon metoduyla ayrılmıştır. Atıklardan ayrılan furfural örneklerinin IRspektrumları ile standart furfuralin IR-spektrumları karşılaştırılmıştır. Fındık kabuklarından farklı sıcaklıklarda aktif karbon elde edilmiştir. Bu aktif karbon kullanılarak organik ve anarganik atıklar adsorbsiyonla uzaklaştırılmıştır.

    19. ELEKTRİKLİ EV ALETLERİNDE CE UYUMLULUĞU VE BİR UYGULAMA

      Directory of Open Access Journals (Sweden)

      Nazmi EKREN

      2009-01-01

      Full Text Available Hızla gelişen teknoloji, artan rekabet ortamı ve kullanıcının bilinçlenmesi gibi nedenlerden dolayı kaliteli üretim yapmanın gerekliliği günümüzde daha da artmıştır. Ürün kalitesinin ve güvenilirliğinin belgelenmesi tüketici açısından şart olmuştur. Ürün güvenliğinin belgelenmesinde kullanılan birçok belge vardır. Bu belgelerden biri de CE belgesidir. Bu makalede, CE işareti ile ilgili temel bilgi verilmiş ve elektrikli ev aletleri için gerekli CE standartları ve testlerinden bahsedilmiştir. Örnek olarak elektrikli ev aletlerinden tost makinesi ele alınmış, incelenmiştir. Tost makinesine CE belgesi almak için EN60335-2-9 direktifine göre gerekli testler yapılmış ve CE belgesi alınmıştır.

    20. Anomalous thermal expansion in YMn2, Y6Mn23 and YMn12

      International Nuclear Information System (INIS)

      Gratz, E.; Gurjazkas, D.; Mueller, H.; Kottar, A.

      1997-01-01

      The thermal expansion coefficient α(T) of YMn 2 , Y 6 Mn 23 and YMn 12 is presented in the temperature range 4.2-1000 K together with α(T) of YCo 2 and YNi 2 . The strong variation of α(T) of the Y-Mn compounds in their paramagnetic state is discussed under the assumption that there exist Mn atoms with different electronic configurations and therefore with different atomic volumes. Changes of the concentration of these different Mn atoms with temperature reveal this anomalous thermal expansion. (orig.)

    1. VeSMEL: A Novel Approach for Distance Management of E-Learning Platforms

      Directory of Open Access Journals (Sweden)

      Bernabe Batchakui

      2011-05-01

      Full Text Available This article presents a novel approach for distance management for e-learning platforms based on VeSMp protocol. VeSMEL results from the integration of VeSMp to xMoodle 2.0 platform that has been developed. It offers a compromise between the mobility of actors and the availability of xMoodle 2.0 content in zones where internet is inaccessible. The GSM system is used like support for communication allowing the actors to reach servers from their cell phone.

    2. Prediction and Observation of Post-Admission Hematoma Expansion in Patients with Intracerebral Hemorrhage

      Science.gov (United States)

      Ovesen, Christian; Havsteen, Inger; Rosenbaum, Sverre; Christensen, Hanne

      2014-01-01

      Post-admission hematoma expansion in patients with intracerebral hemorrhage (ICH) comprises a simultaneous major clinical problem and a possible target for medical intervention. In any case, the ability to predict and observe hematoma expansion is of great clinical importance. We review radiological concepts in predicting and observing post-admission hematoma expansion. Hematoma expansion can be observed within the first 24 h after symptom onset, but predominantly occurs in the early hours. Thus capturing markers of on-going bleeding on imaging techniques could predict hematoma expansion. The spot sign observed on computed tomography angiography is believed to represent on-going bleeding and is to date the most well investigated and reliable radiological predictor of hematoma expansion as well as functional outcome and mortality. On non-contrast CT, the presence of foci of hypoattenuation within the hematoma along with the hematoma-size is reported to be predictive of hematoma expansion and outcome. Because patients tend to arrive earlier to the hospital, a larger fraction of acute ICH-patients must be expected to undergo hematoma expansion. This renders observation and radiological follow-up investigations increasingly relevant. Transcranial duplex sonography has in recent years proven to be able to estimate hematoma volume with good precision and could be a valuable tool in bedside serial observation of acute ICH-patients. Future studies will elucidate, if better prediction and observation of post-admission hematoma expansion can help select patients, who will benefit from hemostatic treatment. PMID:25324825

    3. CrossTalk. The Journal of Defense Software Engineering. Volume 15, Number 12, December 2002

      Science.gov (United States)

      2002-12-01

      Journal of Defense Software Engineering. Volume 15, Number 12, December 2002 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6...You sit backwards on Disneyland rides to see how they do the special effects. • You’ve tried to repair a $5 radio. • You look forward to Christmas so

    4. Association Between the 2014 Medicaid Expansion and US Hospital Finances.

      Science.gov (United States)

      Blavin, Fredric

      2016-10-11

      The Affordable Care Act expanded Medicaid eligibility for millions of low-income adults. The choice for states to expand Medicaid could affect the financial health of hospitals by decreasing the proportion of patient volume and unreimbursed expenses attributable to uninsured patients while increasing revenue from newly covered patients. To estimate the association between the Medicaid expansion in 2014 and hospital finances by assessing differences between hospitals in states that expanded Medicaid and in those states that did not expand Medicaid. Observational study with analysis of data for nonfederal general medical or surgical hospitals in fiscal years 2011 through 2014, using data from the American Hospital Association Annual Survey and the Health Care Cost Report Information System from the US Centers for Medicare & Medicaid Services. Multivariable difference-in-difference regression analyses were used to compare states with Medicaid expansion with states without Medicaid expansion. Hospitals in states that expanded Medicaid eligibility before January 2014 were excluded. Medicaid expansion in 2014, accounting for variation in fiscal year start dates. Hospital-reported information on uncompensated care, uncompensated care as a percentage of total hospital expenses, Medicaid revenue, Medicaid as a percentage of total revenue, operating margins, and excess margins. The sample included between 1200 and 1400 hospitals per fiscal year in 19 states with Medicaid expansion and between 2200 and 2400 hospitals per fiscal year in 25 states without Medicaid expansion (with sample size varying depending on the outcome measured). Expansion of Medicaid was associated with a decline of $2.8 million (95% CI, -$4.1 to -$1.6 million; P policy change on hospitals' overall finances.

    5. TU-A-12A-01: Consistency of Lung Expansion and Contraction During Respiration: Implications for Quantitative Imaging

      International Nuclear Information System (INIS)

      Patton, T; Du, K; Bayouth, J; Christensen, G; Reinhardt, J

      2014-01-01

      Purpose: Four-dimensional computed tomography (4DCT) can be used to evaluate longitudinal changes in pulmonary function. The sensitivity of such measurements to identify function change may be improved with reproducible breathing patterns. The purpose of this study was to determine if inhale was more consistent than exhale, i.e., lung expansion during inhalation compared to lung contraction during exhalation. Methods: Repeat 4DCT image data acquired within a short time interval from 8 patients. Using a tissue volume preserving deformable image registration algorithm, Jacobian ventilation maps in two scanning sessions were computed and compared on the same coordinate for reproducibility analysis. Equivalent lung volumes (ELV) were used for 5 subjects and equivalent title volumes (ETV) for the 3 subjects who experienced a baseline shift between scans. In addition, gamma pass rate was calculated from a modified gamma index evaluation between two ventilation maps, using acceptance criterions of 2mm distance-to-agreement and 5% ventilation difference. The gamma pass rates were then compared using paired t-test to determine if there was a significant difference. Results: Inhalation was more reproducible than exhalation. In the 5 ELV subjects 78.5% of the lung voxels met the gamma criteria for expansion during inhalation when comparing the two scans, while significantly fewer (70.9% of the lung voxels) met the gamma criteria for contraction during exhalation (p = .027). In the 8 total subjects analyzed the average gamma pass rate for expansion during inhalation was 75.2% while for contraction during exhalation it was 70.3%; which trended towards significant (p = .064). Conclusion: This work implies inhalation is more reproducible than exhalation, when equivalent respiratory volumes are considered. The reason for this difference is unknown. Longitudinal investigation of pulmonary function change based on inhalation images appears appropriate for Jacobian-based measure of

    6. Usûlî Kıyasın Bilgi ve Amel Değeri

      Directory of Open Access Journals (Sweden)

      Yrd.Doç.Dr. Temel Kacır

      2016-06-01

      Full Text Available “Ortak bir illete sahip olmaları nedeniyle, aslın hükmünün fer‘e verilmesidir" şeklinde tanımlanan usûlî kıyasın bilgi ve amel değeri, ilk dönemden itibaren tartışma konusu olmuştur. Şöyle ki; hüküm verme yetkisi sadece Şar‘î’e ait olduğu halde usûlî kıyasın dinde hüküm verme anlamına geldiği ve bilgi değerinin de nasslarca yerilmiş zan olduğu gibi bazı argümanlar ileri sürerek usûlî kıyası reddedenler olsa da, çoğunluk tarafından usûlî kıyas aslî ve şer‘î delil olarak kabul edilmiş ve elde edilen bu hüküm ile amel edilmesi gerekli görülmüştür. Bu çalışma, usûlî kıyası kabul eden ve etmeyenlerin görüşlerini mukayese etmenin ötesinde, usûlî kıyasın salt aklî bir çaba olmadığını, kendisi ile ulaşılan bilginin naslarda yerilen zan olmayıp aksine delile dayalı zannın en üst derecesi olduğunu ve bunun da furû fıkıhta amel için yeterli olduğunu naklî ve aklî deliller ile ele alan bir çalışmadır. Kıyasla ilgili genel bir çerçeve çizildikten sonra, usûlî kıyas ve deliller hiyerarşisindeki yeri ve kıyasın bilgi ve amelî değeri ile sınırlandırılan bu makale ile usûlî kıyasın bilgi ve amel değeri konusundaki tartışmalara açıklık getirilmek istenmektedir.

    7. CD4+ virtual memory: Antigen-inexperienced T cells reside in the naïve, regulatory, and memory T cell compartments at similar frequencies, implications for autoimmunity.

      Science.gov (United States)

      Marusina, Alina I; Ono, Yoko; Merleev, Alexander A; Shimoda, Michiko; Ogawa, Hiromi; Wang, Elizabeth A; Kondo, Kayo; Olney, Laura; Luxardi, Guillaume; Miyamura, Yoshinori; Yilma, Tilahun D; Villalobos, Itzel Bustos; Bergstrom, Jennifer W; Kronenberg, Daniel G; Soulika, Athena M; Adamopoulos, Iannis E; Maverakis, Emanual

      2017-02-01

      It is widely accepted that central and effector memory CD4 + T cells originate from naïve T cells after they have encountered their cognate antigen in the setting of appropriate co-stimulation. However, if this were true the diversity of T cell receptor (TCR) sequences within the naïve T cell compartment should be far greater than that of the memory T cell compartment, which is not supported by TCR sequencing data. Here we demonstrate that aged mice with far fewer naïve T cells, respond to the model antigen, hen eggwhite lysozyme (HEL), by utilizing the same TCR sequence as their younger counterparts. CD4 + T cell repertoire analysis of highly purified T cell populations from naive animals revealed that the HEL-specific clones displayed effector and central "memory" cell surface phenotypes even prior to having encountered their cognate antigen. Furthermore, HEL-inexperienced CD4 + T cells were found to reside within the naïve, regulatory, central memory, and effector memory T cell populations at similar frequencies and the majority of the CD4 + T cells within the regulatory and memory populations were unexpanded. These findings support a new paradigm for CD4 + T cell maturation in which a specific clone can undergo a differentiation process to exhibit a "memory" or regulatory phenotype without having undergone a clonal expansion event. It also demonstrates that a foreign-specific T cell is just as likely to reside within the regulatory T cell compartment as it would the naïve compartment, arguing against the specificity of the regulatory T cell compartment being skewed towards self-reactive T cell clones. Finally, we demonstrate that the same set of foreign and autoreactive CD4 + T cell clones are repetitively generated throughout adulthood. The latter observation argues against T cell-depleting strategies or autologous stem cell transplantation as therapies for autoimmunity-as the immune system has the ability to regenerate pathogenic clones. Published by

    8. Türev piyasaları ve vergilendirilmesi

      OpenAIRE

      İşler, İsmail; Utku, Mehmet

      2015-01-01

      Türev piyasaları kavramı, vadeli işlem sözleşmeleri (forward, futures), opsiyon sözleşmeleri, swap sözleşmeleri ve aracı kuruluş varantları işlemlerinin tamamını içermektedir. Bu tür işlemler vadeli işlemlerdir. Vadeli işlemlerin ortak özelliği, ilerideki bir tarihte teslimatı yapılmak üzere herhangi bir malın veya finansal aracın, bugünden alım satımının yapılmasıdır. Bu çalışmada türev araçların tanımları ve vergilendirilmeleri örneklerle açıklanacaktır. The term derivatives market invol...

    9. Tracking lung tissue motion and expansion/compression with inverse consistent image registration and spirometry.

      Science.gov (United States)

      Christensen, Gary E; Song, Joo Hyun; Lu, Wei; El Naqa, Issam; Low, Daniel A

      2007-06-01

      Breathing motion is one of the major limiting factors for reducing dose and irradiation of normal tissue for conventional conformal radiotherapy. This paper describes a relationship between tracking lung motion using spirometry data and image registration of consecutive CT image volumes collected from a multislice CT scanner over multiple breathing periods. Temporal CT sequences from 5 individuals were analyzed in this study. The couch was moved from 11 to 14 different positions to image the entire lung. At each couch position, 15 image volumes were collected over approximately 3 breathing periods. It is assumed that the expansion and contraction of lung tissue can be modeled as an elastic material. Furthermore, it is assumed that the deformation of the lung is small over one-fifth of a breathing period and therefore the motion of the lung can be adequately modeled using a small deformation linear elastic model. The small deformation inverse consistent linear elastic image registration algorithm is therefore well suited for this problem and was used to register consecutive image scans. The pointwise expansion and compression of lung tissue was measured by computing the Jacobian of the transformations used to register the images. The logarithm of the Jacobian was computed so that expansion and compression of the lung were scaled equally. The log-Jacobian was computed at each voxel in the volume to produce a map of the local expansion and compression of the lung during the breathing period. These log-Jacobian images demonstrate that the lung does not expand uniformly during the breathing period, but rather expands and contracts locally at different rates during inhalation and exhalation. The log-Jacobian numbers were averaged over a cross section of the lung to produce an estimate of the average expansion or compression from one time point to the next and compared to the air flow rate measured by spirometry. In four out of five individuals, the average log

    10. Tracking lung tissue motion and expansion/compression with inverse consistent image registration and spirometry

      International Nuclear Information System (INIS)

      Christensen, Gary E.; Song, Joo Hyun; Lu, Wei; Naqa, Issam El; Low, Daniel A.

      2007-01-01

      Breathing motion is one of the major limiting factors for reducing dose and irradiation of normal tissue for conventional conformal radiotherapy. This paper describes a relationship between tracking lung motion using spirometry data and image registration of consecutive CT image volumes collected from a multislice CT scanner over multiple breathing periods. Temporal CT sequences from 5 individuals were analyzed in this study. The couch was moved from 11 to 14 different positions to image the entire lung. At each couch position, 15 image volumes were collected over approximately 3 breathing periods. It is assumed that the expansion and contraction of lung tissue can be modeled as an elastic material. Furthermore, it is assumed that the deformation of the lung is small over one-fifth of a breathing period and therefore the motion of the lung can be adequately modeled using a small deformation linear elastic model. The small deformation inverse consistent linear elastic image registration algorithm is therefore well suited for this problem and was used to register consecutive image scans. The pointwise expansion and compression of lung tissue was measured by computing the Jacobian of the transformations used to register the images. The logarithm of the Jacobian was computed so that expansion and compression of the lung were scaled equally. The log-Jacobian was computed at each voxel in the volume to produce a map of the local expansion and compression of the lung during the breathing period. These log-Jacobian images demonstrate that the lung does not expand uniformly during the breathing period, but rather expands and contracts locally at different rates during inhalation and exhalation. The log-Jacobian numbers were averaged over a cross section of the lung to produce an estimate of the average expansion or compression from one time point to the next and compared to the air flow rate measured by spirometry. In four out of five individuals, the average log

    11. The PREVAIL Study: Primary Outcomes by Site and Extent of Baseline Disease for Enzalutamide-treated Men with Chemotherapy-naïve Metastatic Castration-resistant Prostate Cancer.

      Science.gov (United States)

      Evans, Christopher P; Higano, Celestia S; Keane, Thomas; Andriole, Gerald; Saad, Fred; Iversen, Peter; Miller, Kurt; Kim, Choung-Soo; Kimura, Go; Armstrong, Andrew J; Sternberg, Cora N; Loriot, Yohann; de Bono, Johann; Noonberg, Sarah B; Mansbach, Hank; Bhattacharya, Suman; Perabo, Frank; Beer, Tomasz M; Tombal, Bertrand

      2016-10-01

      Enzalutamide, an oral androgen receptor inhibitor, significantly improved overall survival (OS) and radiographic progression-free survival (rPFS) versus placebo in the PREVAIL trial of men with chemotherapy-naïve metastatic castration-resistant prostate cancer. To assess the effects of enzalutamide versus placebo in patients from PREVAIL based on site and extent of baseline disease. One thousand seven hundred and seventeen asymptomatic or minimally symptomatic patients were randomized to enzalutamide (n=872) or placebo (n=845). Subgroup analyses included nonvisceral (only bone and/or nodal; n=1513), visceral (lung and/or liver; n=204), low-volume bone disease (1 in patients with visceral disease (HR, 0.82; 95% CI, 0.55-1.23). Enzalutamide was well tolerated in patients with or without visceral disease. Enzalutamide provided clinically significant benefits in men with chemotherapy-naïve metastatic castration-resistant prostate cancer, with or without visceral disease, low- or high-volume bone disease, or lymph node only disease. Patients with metastatic castration-resistant prostate cancer-including those with or without visceral disease or widespread bone disease-benefitted from enzalutamide, an active well-tolerated therapy. Copyright © 2016 European Association of Urology. Published by Elsevier B.V. All rights reserved.

    12. Yenidünyanın Bazı Fiziksel ve Kimyasal Özellikleri

      Directory of Open Access Journals (Sweden)

      Feramuz Özdemir

      2015-02-01

      Full Text Available Bu çalışmada Ege, Karadeniz ve özellikle Akdeniz bölgesinde yaygın olarak yetiştirilen yenidünyanın (eriobotrya japonnica L. bazı fiziksel ve kimyasal özellikleri belirlenmiştir.         Araştırmada materyal olarak Antalya Narenciye ve Seracılık Araştırma Enstitüsünün yenidünya bahçesinden sağlanan üç yerli, dört yabancı ve bir yabani olmak üzere toplam sekiz çeşit yenidünya kullanılmıştır. Yeme olumunda toplanan bu meyvelerin ağırlığı çeşide göre 14.00-33.46 g, meyve eti oranı %80.96-87.65, çekirdek sayısı 1-6 adet, çekirdek ağırlığı 2.17-5.35 g ve çekirdek ağırlık oranı %12.35-19.04 olarak saptanmıştır. Kimyasal nitelikler ise pulpta ortalama olarak suda çözünür kurumadde %11.08, pH 3.39, toplam asitlik (malik asit cinsinden 0.75, toplam şeker %9.78, indirgen şeker $9.29, sakkaroz %0.49, kül %0.42, formol sayısı 8.91 ve selüloz % 0.30 olarak bulunmuştur. Meyve pulpundaki mineral madde miktarları ise K 1246.8, Ca 273.1, Na 240.9, Mg 167, Fe 17.2, Cu 9.6, Mn 0.94 ve Zn 5.21 mg/kg olarak belirlenmiştir.

    13. Doğu Karadeniz Bölgesinde Üretilen Balların Kimyasal ve Duyusal Nitelikleri

      Directory of Open Access Journals (Sweden)

      Zehra Güler

      2015-02-01

      Full Text Available Bal, başlıca karbonhidrat (glikoz ve früktoz ve sudan oluşan doğal bir üründür. Bu bileşenlerin yanı sıra protein, enzimler, organik asitler, mineral maddeler ve polen de içermektedir. Bal bileşimini ve özellikle de duyusal niteliğini üretildiği bölgenin florası önemli düzeyde etkilemektedir. Bu nedenle çalışmamız farklı florası ile bilinen Karadeniz bölgesinde (özellikle Hemşin üretilen ballar üzerinde gerçekleştirilmiştir. Üç yıl süresince her yıl Ağustos ayının son haftasında 10 adet bal örneği alınarak toplam 30 adet balın kimyasal ve duyusal nitelikleri incelenmiştir. Ballarda rutubet, invert şeker, sakkaroz, hidroksi metil furfural ve pH gibi nitelikler ortalama olarak sırasıyla % 18,90; % 68,42; % 1,54; 3,83 mg/kg ve 4,96 belirlenmiş ve yalnızca 1 örnekte ticari glikoz varlığına rastlanmıştır. Duyusal nitelikler bakımından ballar, açık sarı renkten-kahverengi ya da kahverengi-kırmızı renge, tat ve kokusu ise yavan bir aroma ve tat'dan çiçek kokusu, tatlı ve kinin acılığı benzeri bir tada kadar değişim göstermiştir. Elde edilen sonuçlara göre, bal örnekleri arasında kimyasal niteliklerin büyük farklılıklar göstermediği ancak duyusal bakımından belirgin bir değişim ortaya koydukları belirlenmiştir.

    14. Lactobacillus ve Bifidobacterium Cinsi Bakterilerin Beta Galaktosidaz Enzim Aktivitelerinin Belirlenmesi

      Directory of Open Access Journals (Sweden)

      Yasemin Kılıç

      2015-02-01

      Full Text Available Bu çalışmada, insan, gıda ve hayvan kaynaklı 39 Lactobacilllus cinsine ait ve yeni doğan gaitasından izole edilmiş 3 Bifidobacterium cinsine ait toplam 42 bakteri kullanılmıştır. O-nitrofenil-beta-D-galaktosit (o-NPG substrat olarak kullanılarak, kültürlerin β-galaktosidaz enzim ve spesifik aktiviteleri belirlenmiştir. Lactobacillus cinsine ait kültürlerden L. fermentum ZYN17 (2.468 U/mg, L. casei LB65 (1.116 U/mg, L. rhamnosus GD11 (1.034 U/mg ve L. acidophilus BAZ36 (0.947 U/mg suşlarının, Bifidobacterium cinsine ait kültürlerden de B. breve A26 (0.726 U/mg suşunun en yüksek spesifik aktivite yeteneğine sahip oldukları tespit edilmiştir. Ayrıca, bakterilerin 5-brom-4-klor-3-indolil-β-D-galaktopiranosit (X-gal substrat bileşiğiyle de nitel olarak enzim aktivitesinin varlığı değerlendirilmiştir. Yüksek spesifik β-galaktozidaz aktivitesi gösteren ZYN17 suşuna ait β-galaktozidaz enziminin optimizasyonu yapılmıştır. β-galaktozidaz enziminin optimum pH’sı 6.8, optimum sıcaklığı 37 ºC ve optimum tamponun potasyum fosfat tamponu olduğu belirlenmiştir.

    15. Kefir ve Kefir Kullanılarak Yapılan Bazı Ürünler

      OpenAIRE

      ESMEK, Emel; GÜZELER, Nuray

      2018-01-01

      Kefir, bakteri ve mayaların etkileriyle kefir daneleri içinde simbiyotik birleşmesi ile oluşan fermente bir süt ürünüdür. Kefir, ağızda hissedilen köpürücü etkisi, tipik maya tadı ve kendisine has belirli aromaları ile bilinir. Kefir fermentasyonun ana ürünleri içeceğin vizkozitesini, asitliğini ve düşük alkol içeriğini gösteren laktik asit, etanol ve karbondioksittir. İkincil bileşenler ise aroma kompozisyonuna katkıda bulunan, diasetil, asetaldehit, etil alkol ve aminoasittir. Kefir, vücudu...

    16. Dynamics of gas cell coalescence during baking expansion of leavened dough.

      Science.gov (United States)

      Miś, Antoni; Nawrocka, Agnieszka; Lamorski, Krzysztof; Dziki, Dariusz

      2018-01-01

      The investigation of the dynamics of gas cell coalescence, i.e. a phenomenon that deteriorates the homogeneity of the cellular structure of bread crumb, was carried out performing simultaneously measurements of the dough volume, pressure, and viscosity. It was demonstrated that, during the baking expansion of chemically leavened wheat flour dough, the maximum growth rate of the gas cell radius determined from the ratio of pressure exerted by the expanded dough to its viscosity was on average four-fold lower than that calculated from volume changes in the gas phase of the dough. Such a high discrepancy was interpreted as a result of the course of coalescence, and a formula for determination of its rate was developed. The coalescence rate in the initial baking expansion phase had negative values, indicating nucleation of newly formed gas cells, which increased the number of gas cells even by 8%. In the next baking expansion phase, the coalescence rate started to exhibit positive values, reflecting dominance of the coalescence phenomenon over nucleation. The maximum coalescence rates indicate that, during the period of the most intensive dough expansion, the number of gas cells decreased by 2-3% within one second. At the end of the formation of bread crumb, the number of the gas cells declined by 55-67% in comparison with the initial value. The correctness of the results was positively verified using X-ray micro-computed tomography. The developed method can be a useful tool for more profound exploration of the coalescence phenomenon at various stages of evolution of the cellular structure and its determinants, which may contribute to future development of more effective methods for improving the texture and sensory quality of bread crumb. Copyright © 2017 Elsevier Ltd. All rights reserved.

    17. Ozonla pestisit giderimi uygulamasının domateste renk ve C vitaminine etklieri

      OpenAIRE

      BALTACI YİĞİT, Havva Merve

      2015-01-01

      Bu tez kapsamında tarla koşullarında yetiştirilen domatesler üç farklı pestisit (neonikotinoidlerden imidacloprid, METI grubundan fenazaquin ve sentetik piretroidlerden lambda cyhalothrin) ile ilaçlanmış ve hasat edilen domateslerde yapılan ozonlama işleminin pestisit giderimine, C vitaminine ve renge etkisi ortaya konulmuştur. Ozonlu su ile yıkama işlemi sonucunda imidacloprid, fenazaquin ve lambda cyhalothrinin sırasıyla; %40,9, %57,8, %20,4 oranında, doğrudan suda yıkama işlemi so...

    18. Van Bölge Eğitim ve Araştırma Hastanesi\\'nde Giardia intestinalis ve Entamoeba histolytica/dispar prevalansı: Dört yıllık izlem

      OpenAIRE

      Bayram, Yasemin; Parlak, Mehmet; Çıkman, Aytekin

      2013-01-01

      Amaç: Çalışmada dört yıllık sürede Giardia intestinalis ve Entemoeba histolytica/ Entemoeba dispar saptanma oranı, yıllar göre dağılımı ile yaş grupları ve cinsiyete göre dağılımının retrospektif olarak belirlenmesi amaçlanmış­tır. Gereç ve yöntem: Ocak 2008 ile Aralık 2011 tarihleri arasında laboratuvarımıza gönderilen 9911 dışkı örneği parazitolojik yönden incelenmiştir. Taze dışkı örneklerinde Entamoeba sp., Giardia trofozoit ve kistlerinin mikrosko­bik teşhisi i...

    19. Tad, Koku ve Renk Katkısı Olarak Kırmızı Biber

      Directory of Open Access Journals (Sweden)

      Atillâ Akgül

      2015-02-01

      Full Text Available Kırmızıbiber, dünya çapında kültürü yapılan ve kullanılan en önemli baharatlardan biridir. Değişik kullanım şekillerinin yanısıra, bölge ve ülkelere göre değişen çok sayıda gıda ürününde yer alması, diğer çoğu baharatlardan farklı olarak yakıcılık ve renk maddelerince zengin olması kırmızıbiberi vazgeçilemez bir tad, koku ve renk materyali durumuna getirmiştir. Bununla birlikte botanik kaynakları ve özellikleri ile ticaret ve bölgesel tüketimlerde çok çeşitli isimle bilinmesi gibi karışıklıklar henüz tam olarak standart çözümlere kavuşturulamamıştır. Yaygınlık kazanan bazı sınıflama ve isimlemelerin kullanılması sürmektedir.

    20. Fibroblast growth factor signaling potentiates VE-cadherin stability at adherens junctions by regulating SHP2.

      Directory of Open Access Journals (Sweden)

      Kunihiko Hatanaka

      Full Text Available The fibroblast growth factor (FGF system plays a critical role in the maintenance of vascular integrity via enhancing the stability of VE-cadherin at adherens junctions. However, the precise molecular mechanism is not well understood. In the present study, we aimed to investigate the detailed mechanism of FGF regulation of VE-cadherin function that leads to endothelial junction stabilization.In vitro studies demonstrated that the loss of FGF signaling disrupts the VE-cadherin-catenin complex at adherens junctions by increasing tyrosine phosphorylation levels of VE-cadherin. Among protein tyrosine phosphatases (PTPs known to be involved in the maintenance of the VE-cadherin complex, suppression of FGF signaling reduces SHP2 expression levels and SHP2/VE-cadherin interaction due to accelerated SHP2 protein degradation. Increased endothelial permeability caused by FGF signaling inhibition was rescued by SHP2 overexpression, indicating the critical role of SHP2 in the maintenance of endothelial junction integrity.These results identify FGF-dependent maintenance of SHP2 as an important new mechanism controlling the extent of VE-cadherin tyrosine phosphorylation, thereby regulating its presence in adherens junctions and endothelial permeability.

    1. Sheath and bulk expansion induced by RF bias in atmospheric pressure microwave plasma

      Science.gov (United States)

      Lee, Jimo; Nam, Woojin; Lee, Jae Koo; Yun, Gunsu

      2017-10-01

      A large axial volume expansion of microwave-driven plasma at atmospheric pressure is achieved by applying a low power radio frequency (RF) bias at an axial location well isolated from the original plasma bulk. The evolution of the plasma plume visualized by high speed ICCD imaging suggest that the free electrons drifting toward the bias electrode cause the prodigious expansion of the sheath, creating a stable plasma stream channel between the microwave and the RF electrodes. For argon plasma in ambient air, enhanced emissions of OH and N2 spectral lines are measured in the extended plume region, supporting the acceleration of electrons and subsequent generation of radical species. The coupling of RF bias with microwave provides an efficient way of enlarging the plasma volume and enhancing the production of radicals. Work supported by the National Research Foundation of Korea under BK21+ program and Grant No. 2015R1D1A1A01061556 (Ministry of Education).

    2. Kapak ve İçindekiler

      Directory of Open Access Journals (Sweden)

      Kapak ve İçindekiler

      2015-12-01

      Full Text Available Süleyman Demirel Üniversitesi Fen Bilimleri Enstitüsü Dergisi, Chemical Abstracts Service , EBSCO Discovery Service, Google Scholar, WorldCat ve Zentralblatt MATH indekslerinde taranmaktadır.Süleyman Demirel University Journal of Natural and Applied Sciences is indexed in Chemical Abstracts Service, EBSCO Discovery Service, Google Scholar, WorldCat and Zentralblatt MATH.

    3. Anonimlik deneyimi ve sosyal medya etkisi

      OpenAIRE

      Aslan, M.Gökhan

      2012-01-01

      116 pages Anonimlik bir kelime olarak çağrıştırdığı ilk anlamlarının ötesinde çok katmanlı bir deneyimi temsil etmektedir. Bu tez çalışmasında amaçlanan, ilk adımda anonimliği sözlük anlamından itibaren başlayarak kapsamlı bir tanımsal analize tabi tutmaktır. Bu analiz dahilinde anonimliğin nitelikleri ve türleri bir bütün olarak ele alınmaktadır. İkinci adımda ise anonimliğin farklı iletişim biçimlerindeki dönüşümünün, paralel sosyal ve teknolojik değişimlerle beraber izi sürülerek son ba...

    4. An FBG Optical Approach to Thermal Expansion Measurements under Hydrostatic Pressure.

      Science.gov (United States)

      Rosa, Priscila F S; Thomas, Sean M; Balakirev, Fedor F; Betts, Jon; Seo, Soonbeom; Bauer, Eric D; Thompson, Joe D; Jaime, Marcelo

      2017-11-04

      We report on an optical technique for measuring thermal expansion and magnetostriction at cryogenic temperatures and under applied hydrostatic pressures of 2.0 GPa. Optical fiber Bragg gratings inside a clamp-type pressure chamber are used to measure the strain in a millimeter-sized sample of CeRhIn₅. We describe the simultaneous measurement of two Bragg gratings in a single optical fiber using an optical sensing instrument capable of resolving changes in length [dL/L = (L- L₀)/L₀] on the order of 10 -7 . Our results demonstrate the possibility of performing high-resolution thermal expansion measurements under hydrostatic pressure, a capability previously hindered by the small working volumes typical of pressure cells.

    5. Acute extracellular fluid volume changes increase ileocolonic resistance to saline flow in anesthetized dogs

      Directory of Open Access Journals (Sweden)

      Santiago Jr. A.T.

      1997-01-01

      Full Text Available We determined the effect of acute extracellular fluid volume changes on saline flow through 4 gut segments (ileocolonic, ileal, ileocolonic sphincter and proximal colon, perfused at constant pressure in anesthetized dogs. Two different experimental protocols were used: hypervolemia (iv saline infusion, 0.9% NaCl, 20 ml/min, volume up to 5% body weight and controlled hemorrhage (up to a 50% drop in mean arterial pressure. Mean ileocolonic flow (N = 6 was gradually and significantly decreased during the expansion (17.1%, P<0.05 and expanded (44.9%, P<0.05 periods while mean ileal flow (N = 7 was significantly decreased only during the expanded period (38%, P<0.05. Mean colonic flow (N = 7 was decreased during expansion (12%, P<0.05 but returned to control levels during the expanded period. Mean ileocolonic sphincter flow (N = 6 was not significantly modified. Mean ileocolonic flow (N = 10 was also decreased after hemorrhage (retracted period by 17% (P<0.05, but saline flow was not modified in the other separate circuits (N = 6, 5 and 4 for ileal, ileocolonic sphincter and colonic groups, respectively. The expansion effect was blocked by atropine (0.5 mg/kg, iv both on the ileocolonic (N = 6 and ileal (N = 5 circuits. Acute extracellular fluid volume retraction and expansion increased the lower gastrointestinal resistances to saline flow. These effects, which could physiologically decrease the liquid volume being supplied to the colon, are possible mechanisms activated to acutely balance liquid volume deficit and excess.

    6. Portsmouth Gaseous Diffusion Plant expansion: final environmental statement. Volume 1

      Energy Technology Data Exchange (ETDEWEB)

      1977-09-01

      Volume 1 is comprised of chapters on: background and description; environmental impacts of add-on gaseous diffusion plant; unavoidable adverse environmental effects; alternatives; relationship between short-term uses and long-term productivity; relationship of program to land-use plans, policies, and controls; irreversible and irretrievable commitments of resources; cost-benefit analysis; and response to comment letters. (LK)

    7. Portsmouth Gaseous Diffusion Plant expansion: final environmental statement. Volume 1

      International Nuclear Information System (INIS)

      1977-09-01

      Volume 1 is comprised of chapters on: background and description; environmental impacts of add-on gaseous diffusion plant; unavoidable adverse environmental effects; alternatives; relationship between short-term uses and long-term productivity; relationship of program to land-use plans, policies, and controls; irreversible and irretrievable commitments of resources; cost-benefit analysis; and response to comment letters

    8. Investigation of Key Parameters of Rock Cracking Using the Expansion of Vermiculite Materials

      Science.gov (United States)

      Ahn, Chi-Hyung; Hu, Jong Wan

      2015-01-01

      The demand for the development of underground spaces has been sharply increased in lieu of saturated ground spaces because the residents of cities have steadily increased since the 1980s. The traditional widely used excavation methods (i.e., explosion and shield) have caused many problems, such as noise, vibration, extended schedule, and increased costs. The vibration-free (and explosion-free) excavation method has currently attracted attention in the construction site because of the advantage of definitively solving these issues. For such reason, a new excavation method that utilizes the expansion of vermiculite with relatively fewer defects is proposed in this study. In general, vermiculite materials are rapidly expanded in volume when they receive thermal energy. Expansion pressure can be produced by thermal expansion of vermiculite in a steel tube, and measured by laboratory tests. The experimental tests are performed with various influencing parameters in an effort to seek the optimal condition to effectively increase expansion pressure at the same temperature. Then, calibrated expansion pressure is estimated, and compared to each model. After analyzing test results for expansion pressure, it is verified that vermiculite expanded by heat can provide enough internal pressure to break hard rock during tunneling work. PMID:28793610

    9. Investigation of Key Parameters of Rock Cracking Using the Expansion of Vermiculite Materia

      Directory of Open Access Journals (Sweden)

      Chi-Hyung Ahn

      2015-10-01

      Full Text Available The demand for the development of underground spaces has been sharply increased in lieu of saturated ground spaces because the residents of cities have steadily increased since the 1980s. The traditional widely used excavation methods (i.e., explosion and shield have caused many problems, such as noise, vibration, extended schedule, and increased costs. The vibration-free (and explosion-free excavation method has currently attracted attention in the construction site because of the advantage of definitively solving these issues. For such reason, a new excavation method that utilizes the expansion of vermiculite with relatively fewer defects is proposed in this study. In general, vermiculite materials are rapidly expanded in volume when they receive thermal energy. Expansion pressure can be produced by thermal expansion of vermiculite in a steel tube, and measured by laboratory tests. The experimental tests are performed with various influencing parameters in an effort to seek the optimal condition to effectively increase expansion pressure at the same temperature. Then, calibrated expansion pressure is estimated, and compared to each model. After analyzing test results for expansion pressure, it is verified that vermiculite expanded by heat can provide enough internal pressure to break hard rock during tunneling work.

    10. Excess Molar Volume, Viscosity and Heat Capacity for the Binary Mixture of p-Xylene and Acetic Acid at Different Temperatures%对二甲苯和醋酸二元液体混合物在不同温度下的超额摩尔体积、粘度和热容

      Institute of Scientific and Technical Information of China (English)

      杨长生; 马沛生; 唐多强; 尹秋响; 赵长伟

      2002-01-01

      Experimental densities, viscosities and heat capacities at different temperatures were presented overthe entire range of mole fraction for the binary mixture of p-xylene and acetic acid. Density values were used in thedetermination of excess molar volumes, VE. At the same time, the excess viscosity and excess molar heat capacitieswere calculated. The values of VE, ηE and cpE were fitted to the Redlich-Kister equation. Good agreements wereobserved. The excess molar volumes are positive with a large maximum value located in the central concentrationrange. The excess viscosity has an opposite trend to the excess molar volume VE. ηE values are negative over theentire range of the mixture. The cure of dependence of cEp on concentration has a special shape. The molecularinteraction between p-xylene and acetic acid is discussed.

    11. Splines and their reciprocal-bases in volume-integral equations

      International Nuclear Information System (INIS)

      Sabbagh, H.A.

      1993-01-01

      The authors briefly outline the use of higher-order splines and their reciprocal-bases in discretizing the volume-integral equations of electromagnetics. The discretization is carried out by means of the method of moments, in which the expansion functions are the higher-order splines, and the testing functions are the corresponding reciprocal-basis functions. These functions satisfy an orthogonality condition with respect to the spline expansion functions. Thus, the method is not Galerkin, but the structure of the resulting equations is quite regular, nevertheless. The theory is applied to the volume-integral equations for the unknown current density, or unknown electric field, within a scattering body, and to the equations for eddy-current nondestructive evaluation. Numerical techniques for computing the matrix elements are also given

    12. Density, excess volume, and excess coefficient of thermal expansion of the binary systems of dimethyl carbonate with butyl methacrylate, allyl methacrylate, styrene, and vinyl acetate at T = (293.15, 303.15, and 313.15) K

      International Nuclear Information System (INIS)

      Wisniak, Jaime; Cortez, Gladis; Peralta, Rene D.; Infante, Ramiro; Elizalde, Luis E.; Amaro, Tlaloc A.; Garcia, Omar; Soto, Homero

      2008-01-01

      Densities of the binary systems of dimethyl carbonate with butyl methacrylate, allyl methacrylate, styrene, and vinyl acetate have been measured as a function of the composition at (293.15, 303.15, and 313.15) K at atmospheric pressure, using an Anton Paar DMA 5000 oscillating U-tube densimeter. The excess molar volumes are negative for the (dimethyl carbonate + vinyl acetate) system and positive for the three other binaries, and become more so as the temperature increases from (293.15 to 313.15) K. The apparent volumes were used to calculate the values of the partial excess molar volumes at infinite dilution. The excess coefficient of thermal expansion is positive for the four binary systems. The calculated excess molar volumes were correlated with the Redlich-Kister equation and with a series of Legendre polynomials. An explanation of the results is offered based on the FT-IR (ATR) spectra of several mixtures of the different systems

    13. Density, excess volume, and excess coefficient of thermal expansion of the binary systems of dimethyl carbonate with butyl methacrylate, allyl methacrylate, styrene, and vinyl acetate at T = (293.15, 303.15, and 313.15) K

      Energy Technology Data Exchange (ETDEWEB)

      Wisniak, Jaime [Department of Chemical Engineering, Ben-Gurion University of the Negev, Beer-Sheva 84105 (Israel)], E-mail: wisniak@bgumail.bgu.ac.il; Cortez, Gladis; Peralta, Rene D.; Infante, Ramiro; Elizalde, Luis E. [Centro de Investigacion en Quimica Aplicada, Saltillo 25253, Coahuila (Mexico); Amaro, Tlaloc A.; Garcia, Omar; Soto, Homero [Facultad de Ciencias Quimicas, Universidad Autonoma de Coahuila, Saltillo 25280, Coahuila (Mexico)

      2008-12-15

      Densities of the binary systems of dimethyl carbonate with butyl methacrylate, allyl methacrylate, styrene, and vinyl acetate have been measured as a function of the composition at (293.15, 303.15, and 313.15) K at atmospheric pressure, using an Anton Paar DMA 5000 oscillating U-tube densimeter. The excess molar volumes are negative for the (dimethyl carbonate + vinyl acetate) system and positive for the three other binaries, and become more so as the temperature increases from (293.15 to 313.15) K. The apparent volumes were used to calculate the values of the partial excess molar volumes at infinite dilution. The excess coefficient of thermal expansion is positive for the four binary systems. The calculated excess molar volumes were correlated with the Redlich-Kister equation and with a series of Legendre polynomials. An explanation of the results is offered based on the FT-IR (ATR) spectra of several mixtures of the different systems.

    14. Düzce Yöresinde Su Kullanımı ve Tabansuyu

      Directory of Open Access Journals (Sweden)

      Selçuk ÖZMEN

      2014-06-01

      Full Text Available Bu çalışmada, Düzce yöresinde su kullanımı ve tabansuyu durumu irdelenmiştir. Yörede bulanan toplam tarım arazilerinin % 36’sı sulanmakta olup, bu arazilerde ağırlıklı olarak yüzey sulama yöntemi uygulanmaktadır. Yapılan çalışmalar sonucunda; bu yörede sulama ile ilgili daha önce yapılan çalışmaların yetersiz olduğu ve basınçlı sulama tekniklerinin uygulama oranın sadece % 5-10 aralığında değiştiği saptanmıştır. Bununla birlikte, yörenin değişken topografik yapısı nedeniyle kış ve ilkbahar aylarında taban suyunun arttığı gözlenmiştir. Yörede sulama ve tabansuyu kaynaklı tuzluluk problemi olmadığı belirlenmiştir

    15. Thermal expansion

      International Nuclear Information System (INIS)

      Yun, Y.

      2015-01-01

      Thermal expansion of fuel pellet is an important property which limits the lifetime of the fuels in reactors, because it affects both the pellet and cladding mechanical interaction and the gap conductivity. By fitting a number of available measured data, recommended equations have been presented and successfully used to estimate thermal expansion coefficient of the nuclear fuel pellet. However, due to large scatter of the measured data, non-consensus data have been omitted in formulating the equations. Also, the equation is strongly governed by the lack of appropriate experimental data. For those reasons, it is important to develop theoretical methodologies to better describe thermal expansion behaviour of nuclear fuel. In particular, first-principles and molecular dynamics simulations have been certainly contributed to predict reliable thermal expansion without fitting the measured data. Furthermore, the two theoretical techniques have improved on understanding the change of fuel dimension by describing the atomic-scale processes associated with lattice expansion in the fuels. (author)

    16. MONSOONS MUDE AND GOLD MUSONLAR GEMİ VE ALTIN

      Directory of Open Access Journals (Sweden)

      Paul LUNDE

      2009-12-01

      Full Text Available The “global economy” of the Middle Ages was created by linking the Indian Ocean trading networks with those of the Mediterranean Sea and its African and European hinterlands. These products, together with ceramics, textiles and sugar provided from Egypt and Syria, reached European markets almost exclusively through the Italian maritime republics of Amalfi, Pisa, Genoa and Venice. Especially the direction of the monsoon winds in the Indian Ocean and the course of the Venice trade ships were at the same direction. Thereby, Venice trade ships set out toward the end of August and made their way slowly through the Adriatic and the Aegean to Cyprus and Alexandria, timing their arrival there to coincide with the availability of monsoon-borne and by this way the products which are ned carried through Europe. İt is important to emphasize this subject that North Europe economy depends on this Monsoons where they became at Indian Ocean. As a maritime republic dedicated itself to the international trade, Venice was an anomaly in a feudal Europe that measured wealth by land, not money. Therefor this idea were encouraging their believing about ending the monopoly of the Muslim trade at the Indian Ocean. Ortaçağın global ekonomisini Hint Okyanusu ticaret hattı ile Akdeniz, Afrika ve Avrupa Hinterlantları arasındaki ticaret bağlantısı teşkil ediyordu. Avrupa ekonomisindeki gelişmelere paralel olarak Batı dünyasının gereksinim duyduğu ve Mısır ile Suriye’den tedarik edilen şeker, tekstil, seramik gibi ürünler Amalfi, Pisa, Ceneviz ve Venedik gibi İtalyan Cumhuriyetleri aracılığıyla Avrupa pazarlarına taşınmaktaydı. Özellikle Hint Okyanusu üzerindeki muson rüzgârlarının yönleriyle Venedik ticaret gemilerinin rotaları aynı doğrultudaydı. Bu suretle Ağustos ayının sonuna doğru İtalya’dan ayrılan gemiler, Adriyatik, Ege ve Kıbrıs rotasından İskenderiye’ye ulaştığı esnada musonlarla kar

    17. 2-ALLİL-6,6'-[(3,3'-DİMETOKSİ[1,1'-BİFENİL]-4,4'-DİYİLBİS(NİTRİLOMETİLİDEN]BİS-FENOLÜN MİKRODALGA VE GELENEKSEL ISITMA YOLUYLA SENTEZİ, YAPI KARAKTERİZASYONU VE TAUTOMERİK ÖZELLİKLERİNİN DENEYSEL VE TEORİK OLARAK İNCELENMESİ

      Directory of Open Access Journals (Sweden)

      Emel ERMİŞ

      2015-05-01

      Full Text Available 2-Allil-6,6'-[(3,3'-dimetoksi[1,1'-bifenil]-4,4'-diyilbis(nitrilometiliden]bis-fenol (3 Schiff bazı bileşiği, 3-allilsalisilaldehitin (1 o-dianisidin (2 ile kondenzasyon reaksiyonundan geleneksel ısıtma ve mikrodalga-ışınlama yöntemi kullanılarak sentezlendi. Bileşik (3’ün kimyasal yapısı element analizi, FTIR, 1H NMR, ve 13C NMR teknikleri kullanılarak karakterize edildi. Bileşiğin farklı organik çözücülerde fenol-imin (O-H…N ve keto-amin (O…H-N tautomerik dengeleri, UV-görünür bölge spektrofotometrik yöntem kullanılarak incelendi ve keto-amin yüzdeleri hesaplandı. Ayrıca, bileşiğin geometrisi, farklı çözücülerdeki fenol-imin ve keto-amin tautomerlerinin enerjisi, moleküliçi O-H…N ve O…H-N hidrojen bağ uzunluğu, UV-görünür bölge uyarılma enerjisi ve ossilatör kuvveti DFT (B3LYP/6-311+G(d,p hesaplama yöntemiyle teorik olarak hesaplandı ve hesaplamalar deneysel sonuçlar ile karşılaştırıldı.

    18. Low-temperature thermal expansion

      International Nuclear Information System (INIS)

      Collings, E.W.

      1986-01-01

      This chapter discusses the thermal expansion of insulators and metals. Harmonicity and anharmonicity in thermal expansion are examined. The electronic, magnetic, an other contributions to low temperature thermal expansion are analyzed. The thermodynamics of the Debye isotropic continuum, the lattice-dynamical approach, and the thermal expansion of metals are discussed. Relative linear expansion at low temperatures is reviewed and further calculations of the electronic thermal expansion coefficient are given. Thermal expansions are given for Cu, Al and Ti. Phenomenologic thermodynamic relationships are also discussed

    19. apılan Sporun Karakteristiği Solunum Fonksiyonlarını Etkiler mi? Voleybol ve Judo Sporcularının Karşılaştırılması

      Directory of Open Access Journals (Sweden)

      Tuğba KOCAHAN

      2017-06-01

      Full Text Available Sporcular yapılan spora bağlı olarak farklı fizyolojik adaptasyonlar geliştirirler. Solunum fonksiyonları da bu adaptasyonlardan etkilenir. Çalışmamızın amacı karakteristiği birbirinden oldukça farklı olan voleybol ve judo sporunun solunum fonksiyonları üzerindeki etkisini karşılaştırmaktır. Çalışmaya ortalama yaşı 15,50±1,08 yıl olan 12 erkek voleybol sporcusu ile ortalama yaşı 15,10±1.37 yıl olan 10 erkek judo sporcusu dahil edildi. Sporcuların solunum fonksiyonları spirometre ile test edildi. Sporcuların forced expiratory volume-zorlu ekspiratuar hacim (FEV, forced expiratory volume in one second-bir saniyedeki zorlu ekspiratuar hacim (FEV1, forced vital capasity- zorlu vital kapasite (FVC, forced ekspiratuary volume-zorlu ekspiraturar volüm/ forced vital capasity-zorlu vital kapasite yüzdesi (FEV1/FVC%, peak expiratory flow- tepe akım hızı (PEF, forced expiratory volume at %25- %25’deki zorlu ekspiratuar hacim (FEV25, forced expiratory volume at %50- %50’deki zorlu ekspiratuar hacim (FEV50, forced expiratory volume at %75- %75’deki zorlu ekspiratuar hacim (FEV75 değerleri kaydedildi ve SPSS istatistiksel analiz programı kullanılarak veriler karşılaştırıldı. Sporcuların yaşları arasında anlamlı bir fark bulunamamıştır (p>0,05. Boy ve kilo değerleri arasında anlamlı bir fark mevcut olsa da söz konusu bu fark BKI (Beden Kitle İndeksi için geçerli değildir (p>0,05. Spirometrik değişkenlerden FEV1/FVC% haricindeki tüm değerler voleybol sporcularında daha yüksek belirlenmiştir ve iki grup arasındaki değişkenler arasındaki farkın tamamı anlamlılık düzeyine ulaşmıştır (p<0,05. Voleybol sporunda, judo sporuna kıyasla solunum sistemi üzerine düşen yükün daha fazla olması bu sporcuların solunum fonksiyonlarının judo sporcularından yüksek çıkmasına sebep olmuştur. Bu çalışma ile yapılan sporun karakteristiğinin solunum sistemi

    20. Mersin (Myrtus communis L. Meyvesinin bazı Fiziksel ve Kimyasal Özellikleri

      Directory of Open Access Journals (Sweden)

      Musa Özcan

      2015-02-01

      Full Text Available İçel’den (Büyükeceli-Gülnar toplanan farklı büyüklük ve renklerdeki mersin (Myrtus communis L. meyvelerinin fiziksel ve kimyasal özellikleri belirlenmiştir. Mor meyvelerde antosiyanin tespit edilirken beyaz renklide bulunmamıştır. Mor meyvelerde tanen miktarı beyazlara göre oldukça yüksektir. Titrasyon asitliği mor meyvelerde aynı olup, beyaza göre yüksektir. Meyveler mineral bakımından zengindir ve en yüksek olarak potasyum belirlenmiştir.

    1. Mersin (Myrtus communis L.) Meyvesinin bazı Fiziksel ve Kimyasal Özellikleri

      OpenAIRE

      Özcan, Musa; Akbulut, Mehmet

      1998-01-01

      İçel’den (Büyükeceli-Gülnar) toplanan farklı büyüklük ve renklerdeki mersin (Myrtus communis L.) meyvelerinin fiziksel ve kimyasal özellikleri belirlenmiştir. Mor meyvelerde antosiyanin tespit edilirken beyaz renklide bulunmamıştır. Mor meyvelerde tanen miktarı beyazlara göre oldukça yüksektir. Titrasyon asitliği mor meyvelerde aynı olup, beyaza göre yüksektir. Meyveler mineral bakımından zengindir ve en yüksek olarak potasyum belirlenmiştir. 

    2. İCMÂ TEORİSİ VE BÂKILLÂNÎ’NİN ETKİSİ

      Directory of Open Access Journals (Sweden)

      Taha NAS

      2014-12-01

      Full Text Available Bu makalede, ilk dönem usûlcülerinden Bâkıllânî’nin icmâ anlayışı, kendisinden önceki iki usûlcü Şafiî ve Cessâs ile sonraki iki usûlcü Cüveynî ve Gazzâlî’nin görüşleri de dikkate alınarak incelenmiştir. Böylece Bâkıllânî’nin görüşleri ile birlikte ilk dönemlerde icmâın gelişimi bir nebze ortaya konulmaya çalışılmıştır. Hanefî usûlcü Cessâs’tan sonra kelamcıusûlcü olarak ilk defa icmâı geniş bir şekilde ele alan Bâkıllânî, aynızamanda icmâıilk tanımlayan usûlcüllerden biri olmuştur. Daha sonra icmâın gerçekleşmesinin imkânını tartışmış ve bunun mümkün olduğunu, ilk dönemlerde bunun sabit olduğunu ve icmâın imkânını ve sübutunu reddedenlerin iddialarının geçersizliğini ifade etmiştir. İcmâın hücciyyetinin delillerinin akli değil, naklî olacağını söylemiş ve bu bağlamda Kur’an’dan bazı ayetleri ve bazı hadislerin ortak manasını delil olarak aktarmıştır. Ayrıca icmâın gerçekleşmesinin şartlarını, geçerli olduğu alanları ve diğer bir takım fer’î meseleleri incelemiştir.

    3. Particle Impact Erosion. Volume 4. User’s Manual Erosion Prediction Procedure for Rocket Nozzle Expansion Region

      Science.gov (United States)

      1983-05-01

      empirical erosion model, with use of the debris-layer model optional. 1.1 INTERFACE WITH ISPP ISPP is a collection of computer codes designed to calculate...expansion with the ODK code, 4. A two-dimensional, two-phase nozzle expansion with the TD2P code, 5. A turbulent boundary layer solution along the...INPUT THERMODYNAMIC DATA FOR TEMPERATURESBELOW 300°K OIF NEEDED) NO A• 11 READ SSP NAMELIST (ODE. BAL. ODK . TD2P. TEL. NOZZLE GEOMETRY) PROfLM 2

    4. Hizmet Öncesi ve İçi İngilizce Öğretmenlerinin Özyeterlik Algıları ve Öğretmeye Yönelik Endişeleri

      Directory of Open Access Journals (Sweden)

      Demet Yaylı

      2015-05-01

      Full Text Available Bu çalışma hizmet öncesi ve hizmet içi İngilizce öğretmenlerinin özyeterlik algılarını, öğretmeye yönelik endişelerini ve endişe ve özyeterlik ölçeklerinin alt boyutlarından elde edilen bulguların kendi içlerinde ve birbirleriyle olan ilişkilerini incelemiştir. Bu amaçla, Öğretmen Özyeterlik Ölçeği ve Öğretmeye Yönelik Endişeler Ölçeği kullanılmıştır. Öncelikle, hizmet içi İngilizce öğretmenlerinin özyeterlik algısı daha yüksek gözlenirken, hizmet öncesi İngilizce öğretmenlerinin ise endişe düzeyi daha yüksek olarak izlenmiştir. Ayrıca, hem hizmet öncesi hem de hizmet içi İngilizce öğretmenlerinden elde edilen özyeterlik ve endişe ölçeklerinin alt boyutlarında gözlenen bulgular kendi içinde karşılaştırıldığında olumlu yönde güçlü bir ilişki ortaya koymaktadır. Diğer bir deyişle, özyeterlik alt boyutlarından birinde gözlenecek bir artış başka bir alt boyutta da artışa neden olabilecektir. Son olarak, bu alt boyutlardan elde edilen bulgular endişe ve özyeterlik olarak birbirleriyle karşılaştırıldığında ise olumsuz yönde dengeli bir ilişki gözlenmiştir. Bu da öğretmenin özyeterlik algısının yüksek olmasının endişe düzeyinin düşük olmasını beraberinde getireceği şeklinde yorumlanabilir

    5. Interfacing with in-Situ Data Networks during the Arctic Boreal Vulnerability Experiment (ABoVE)

      Science.gov (United States)

      McInerney, M.; Griffith, P. C.; Duffy, D.; Hoy, E.; Schnase, J. L.; Sinno, S.; Thompson, J. H.

      2014-12-01

      The Arctic Boreal Vulnerability Experiment (ABoVE) is designed to improve understanding of the causes and impacts of ecological changes in Arctic/boreal regions, and will integrate field-based studies, modeling, and data from airborne and satellite remote sensing. ABoVE will result in a fuller understanding of ecosystem vulnerability and resilience to environmental change in the Arctic and boreal regions of western North America, and provide scientific information required to develop options for societal responses to the impacts of these changes. The studies sponsored by NASA during ABoVE will be coordinated with research and in-situ monitoring activities being sponsored by a number of national and international partners. The NASA Center for Climate Simulation at the Goddard Space Flight Center has partnered with the NASA Carbon Cycle & Ecosystems Office to create a science cloud designed for this field campaign - the ABoVE Science Cloud (ASC). The ASC combines high performance computing with emerging technologies to create an environment specifically designed for large-scale modeling, analysis of remote sensing data, copious disk storage with integrated data management, and integration of core variables from in-situ networks identified by the ABoVE Science Definition Team. In this talk, we will present the scientific requirements driving the development of the ABoVE Science Cloud, discuss the necessary interfaces, both computational and human, with in-situ monitoring networks, and show examples of how the ASC is being used to meet the needs of the ABoVE campaign.

    6. Volume do embrião estimado pela ultra-sonografia tridimensional entre a sétima e a décima semana de gestação Embryo volume estimated by three-dimensional ultrasonography at seven to ten weeks of pregnancy

      Directory of Open Access Journals (Sweden)

      João Bortoletti Filho

      2008-10-01

      Full Text Available OBJETIVO: avaliar a evolução do volume do embrião (VE entre a sétima e a décima semana de gestação por meio da ultra-sonografia tridimensional. MÉTODOS: realizou-se um estudo de corte transversal com 63 gestantes normais entre a sétima e a décima semana. Os exames ultra-sonográficos foram realizados por meio de um transdutor endocavitário volumétrico. Para o cálculo do VE, utilizou-se o método VOCAL (Virtual Organ Computer-aided Analysis com ângulo de rotação de 12º, com delimitação de 15 planos seqüenciais. Para o VE foram calculadas médias, medianas, desvios padrão e valores máximo e mínimo em todas as idades gestacionais. Para se avaliar a correlação entre o VE e o comprimento cabeça-nádega (CCN foi criado gráfico de dispersão, sendo o ajuste realizado pelo coeficiente de determinação (R². Para se determinarem intervalos de referência do VE em função do CCN, utilizou-se a seguinte fórmula: percentil =VE+K versus dp, com K=1,96. RESULTADOS: o CCN variou de 9,0 a 39,7 mm, com média de 23,9 mm (±7,9 mm, enquanto o VE variou de 0,1 a 7,6 cm³, com média de 2,7 cm³ (±3,2 cm³. O VE foi altamente correlacionado com o CCN, sendo que o melhor ajuste foi obtido com regressão quadrática (VE=0,165 - 0,055 x CCN + 0,005 x CCN²; R²=0,853. O VE médio variou de 0,1 (-0,3 a 0,5 cm³ a 6,7 cm³ (3,8 a 9,7 cm³ no intervalo de 9 a 40 mm do CCN. Neste intervalo o VE aumentou 67 vezes, enquanto o CCN aumentou apenas 4,4 vezes. CONCLUSÕES: o VE é um parâmetro mais sensível que o CCN para avaliar o crescimento embrionário entre a sétima e a décima semana de gestação.PURPOSE: to evaluate the embryo's volume (EV between the seventh and the tenth gestational week, through tridimensional ultrasonography. METHODS: a transversal study with 63 normal pregnant women between the seventh and the tenth gestational week. The ultrasonographical exams have been performed with a volumetric abdominal transducer. Virtual

    7. Emeklilik Fonları ve Finansal İstikrar: Şili ve Türkiye Örneklerinden Dersler(Pension Funds and Financial Stability: Lessons from Chile and Turkey

      Directory of Open Access Journals (Sweden)

      Vedat Akgiray

      2016-03-01

      Full Text Available Emeklilik fonları, i uzun vadeli yatırım perspektifine sahip olması, ii finansal piyasalardaki oynaklığı uzun vadeye yayarak absorbe edebilmesi, ve iii yatırımlarını hisse senedi ve altyapı fonları ile reel ekonomiye aktarmaları sayesinde; finansal piyasalardaki oynaklığın azalmasına katkıda bulunmaktadır. Bu çalışma, gelişmekte olan ülkelerde (GOÜ,  emeklilik fonlarının ekonomideki payının en düşük olduğu ülkelerden Türkiye'de (%2 ve en yüksek olduğu ülkelerden Şili'de (%66 emeklilik sistemlerinin karşılaştırmalı analizini sunarak, emeklilik fonlarının finansal piyasalardaki oynaklığa olan etkisini 2004-2014 dönemi için incelemektedir. Çalışma aynı zamanda, Türkiye’de uygulanması planlanan ‘otomatik katılım sistemi’ ve bu sistemi tamamlayıcı ‘fon ürünleri’ üzerine politika önerilerini de kapsamaktadır.

    8. Rodinný dům ve svahu

      OpenAIRE

      Hrubý, Libor

      2013-01-01

      Bakalářská práce, zabývající se projektovou dokumentací stavební části ve stupni pro provedení stavby na novostavbu samostatně stojícího rodinného domu ve svahu. Objekt je dvoupodlažní, podsklepený. Svislé konstrukce z vápenopískového zdícího systému KM Beta Sendwix. Stropní konstrukce z předpjatých stropních panelů Spiroll. Zastřešení provedeno pultovou vegetační střechou se sklonem 10%, plochou střechou s terasovou úpravou a plochou vegetační střechou. Dispozičně je objekt rozdělen na klido...

    9. Afyon, Konya ve Eskişehir İllerinde Keçilerde Pestivirus ve Parainfluenzavirus Tip 3 Enfeksiyonlarının Serolojik Olarak Araştırılması

      OpenAIRE

      Gür, S; Erol, N; Yapıcı, O

      2014-01-01

      Bu çalışmada sağlıklı ve respiratorik-reprodüktif bozukluklar görülen keçi sürülerinde Pestivirus ve Parainfluenzavirus 3 (PI-3) enfeksiyonları serolojik olarak araştırıldı. Afyonkarahisar, Konya ve Eskişehir illerindeki 7 sürüden toplam 1346 kan örneği elde edildi. Mikronötralizasyon test sonucuna göre, sürü bazında pestivirus spesifik antikorların %35.2 ile %78.8 arasında değiştiği belirlenirken PI-3 için %17.5 ile %62 aralığında olduğu tespit edildi. Toplamda, 933 (%69.3) ve 584 (%43.3) ke...

    10. Digital evaluation of orbital development after self-inflating hydrogel expansion in Chinese children with congenital microphthalmia.

      Science.gov (United States)

      Hou, Zhijia; Xian, Junfang; Chang, Qinglin; Wei, Wenbin; Li, Dongmei

      2016-05-01

      Assessment of the growth of bony orbit in children with blind microphthalmia is essential to its management. In this study, variables were measured to evaluate the development of the bony microphthalmic orbits after treatment with self-inflating hydrogel expanders. This is a retrospective study with an interventional case series. Thirteen pediatric patients with congenital unilateral blind microphthalmia who had undergone tissue expansion with hydrogel expanders and computed tomography (CT) scanning before and after operation were included in the study. The orbital volume, depth, width, and height and retardation of the orbital rims before and after treatment were measured and analyzed using the iPlan Cranial Software. The mean age at the time of first implantation was 44 months (range, 3-113 months). Of the 13 patients, eleven received orbital expansion, while two received socket expansion. In the orbital expansion group, the mean microphthalmic/contralateral ratio (MCR) of orbital volume was 79.3% before surgery, which increased to 89.8% 3 years post operation (P development of inferior and lateral rims showed the greatest retardation before treatment; the retardation of these two rims decreased significantly at the final measurement (P = 0.004). It is also noted that the development of the microphthalmic orbits was limited in the two patients who only underwent socket expansion. The affected orbit enlarged in children with congenital blind microphthalmia following treatment with hydrogel expanders; this suggested that microphthalmia-associated orbital asymmetry can be treated with self-inflating hydrogel expanders. Copyright © 2016 British Association of Plastic, Reconstructive and Aesthetic Surgeons. Published by Elsevier Ltd. All rights reserved.

    11. GELECEĞİN FİNANSMAN TEKNİĞİ: BARTER ve MUHASEBELEŞTİRİLMESİ

      OpenAIRE

      ATABEY, N. Ata; YILMAZ, Baki

      2001-01-01

      Barter, ekonomik kriz dönemlerinde mal ve hizmetlerin takas yolu ile satıldığı ve satın alındığı bir pazarda paranın maliyetini en az düzeye indirmek için geliştirilmiş alternatif finansman tekniklerinden biridir. Barter sistemi, işletmelerde pazarlama, satınalma ve finansman fonksiyonlarını bir arada yürüten barter organizasyonları sayesinde gelişerek yaygınlaşmaktadır. Çalışmamızda barter tekniğinin tanıtılması, işleyişi ve muhasebeleştirilmesi üzerinde durulmuştur....

    12. Türkiye’de Yetiştirilen Nohut Çeşitlerinin Pişme Kalitesi ve Kompozisyonu (İngilizce

      Directory of Open Access Journals (Sweden)

      Recai Ercan

      2015-02-01

      Full Text Available Türkiye’de 2 bölgede yetiştirilen 7 nohut genotiplerinin fiziksel kriterleri ve pişme kalitesi ile mineral madde, tiyamin ve riboflavin miktarları saptanmıştır. Şişme indeksi, hidrasyon indeksi, kuru ve yaş pişme süresi ile K, Ca, Mg, Na ve riboflavin miktarları başlıca genotipinden etkilenmiştir. Kuru ve yaş ağırlık, kuru ve yaş hacim, hidrasyon ve şişme kapasitesi ile Cu, Zn ve tiyamin miktarı ise çevreden etkilenmiştir. Zn ve P miktarı önemli düzeyde (p<0.05 pişme süresi eli ilişkili olmuştur. Şişme indeksi ise kuru pişme süresi ile önemli düzeyde (p<0.01 ilişkili olmuştur.

    13. ALTERNATİF DİZEL MOTOR YAKITI OLARAK BİYODİZEL VE ETANOLÜN KARŞILAŞTIRILMASI

      Directory of Open Access Journals (Sweden)

      Nazım USTA

      2005-03-01

      Full Text Available Biyodizel ve etanol, dizel motorlar için yenilenebilir alternatif yakıtlardır ve farklı oranlarda No. 2 dizel yakıta karıştırılarak dizel motorlarda kullanılabilirler. Etanol tek bir kimyasal yapıya ve belli özelliklere sahip yakıt olmasına rağmen, biyodizellerin özellikleri elde edildikleri yağın cinsine ve esterleştirme metodlarına bağlı olarak değişmektedir. Bu çalışmada etanol ve iki farklı biyodizelin özellikleri No. 2 dizel yakıt ile karşılaştırılmış, etanol ve biyodizellerin ön yanma odalı turbo dizel bir motorun performans ve emisyonlarına etkileri incelenmiştir. Kullanılan alternatif yakıtlar CO, is ve SO2 emisyonlarının azalmasını sağlarken, NOx emisyonunda artışa sebep olmuştur. Etanol ilavesi güçte bir miktar düşmeye sebep olurken, biyodizel ilavesi dizel yakıta göre çok az oranda güç artışı sağlamıştır.

    14. Menemen Ekolojik Koşullarında Lavanta (Lavandula spp.) Tür ve Çeşitlerinin Morfolojik, Verim ve Kalite Özelliklerinin Belirlenmesi

      OpenAIRE

      Karık, Ünal; Çiçek, Fatih; Çınar, Orçun

      2017-01-01

      Bu çalışma Menemen ekolojik koşullarında lavanta (Lavandula spp.) tür ve çeşitlerininmorfolojik, verim ve kalite özelliklerini belirlemek amacı ile 2015-2016yılları arasında yürütülmüştür. Çalışmada 2 farklı türe ait 8 farklı ticarilavanta çeşidi kullanılmıştır. 2 yıl sonucunda elde edilen veriler ışığında türve çeşitler arasında önemli farklılıklar bulunduğu tespit edilmiştir. Lavandintipi çeşitler, verim özellikleri açısından lavander tipi çeşitlerin önünegeçerken,  uçucu yağ oranı ve uçucu...

    15. Rapid estimate of solid volume in large tuff cores using a gas pycnometer

      International Nuclear Information System (INIS)

      Thies, C.; Geddis, A.M.; Guzman, A.G.

      1996-09-01

      A thermally insulated, rigid-volume gas pycnometer system has been developed. The pycnometer chambers have been machined from solid PVC cylinders. Two chambers confine dry high-purity helium at different pressures. A thick-walled design ensures minimal heat exchange with the surrounding environment and a constant volume system, while expansion takes place between the chambers. The internal energy of the gas is assumed constant over the expansion. The ideal gas law is used to estimate the volume of solid material sealed in one of the chambers. Temperature is monitored continuously and incorporated into the calculation of solid volume. Temperature variation between measurements is less than 0.1 degrees C. The data are used to compute grain density for oven-dried Apache Leap tuff core samples. The measured volume of solid and the sample bulk volume are used to estimate porosity and bulk density. Intrinsic permeability was estimated from the porosity and measured pore surface area and is compared to in-situ measurements by the air permeability method. The gas pycnometer accommodates large core samples (0.25 m length x 0.11 m diameter) and can measure solid volume greater than 2.20 cm 3 with less than 1% error

    16. Micro-CT evaluation and histological analysis of screw-bone interface of expansive pedicle screw in osteoporotic sheep.

      Science.gov (United States)

      Wan, Shi-yong; Lei, Wei; Wu, Zi-xiang; Lv, Rong; Wang, Jun; Fu, Suo-chao; Li, Bo; Zhan, Ce

      2008-04-01

      To investigate the properties of screw-bone interface of expansive pedicle screw (EPS) in osteoporotic sheep by micro-CT and histological observation. Six female sheep with bilateral ovariectomy-induced osteoporosis were employed in this experiment. After EPS insertion in each femoral condyle, the sheep were randomly divided into two groups: 3 sheep were bred for 3 months (Group A), while the other 3 were bred for 6 months (Group B). After the animals being killed, the femoral condyles with EPS were obtained, which were three-dimensionally-imaged and reconstructed by micro-CT. Histological evaluation was made thereafter. The trabecular microstructure was denser at the screw-bone interface than in the distant parts in expansive section, especially within the spiral marking. In the non-expansive section, however, there was no significant difference between the interface and the distant parts. The regions of interest (ROI) adjacent to EPS were reconstructed and analyzed by micro-CT with the same thresholds. The three-dimensional (3-D) parameters, including tissue mineral density (TMD), bone volume fraction (BVF, BV/TV), bone surface/bone volume (BS/BV) ratio, trabecular thickness (Tb.Th), and trabecular separation (Tb.Sp), were significantly better in expansive sections than non-expansive sections (P less than 0.05). Histologically, newly-formed bony trabeculae crawled along the expansive fissures and into the center of EPS. The newly-formed bones, as well as the bones at the bone-screw interface, closely contacted with the EPS and constructed four compartments. The findings of the current study, based on micro-CT and histological evaluation, suggest that EPS can significantly provide stabilization in osteoporotic cancellous bones.

    17. Uygulamalı Bilimler ve Mühendislik

      Directory of Open Access Journals (Sweden)

      Edip ŞENYÜREK

      2012-12-01

      Full Text Available İnternet üzerinden sanal firmalar aracılığıyla alışveriş yapmak artan ilgi görmektedir. Müşteriler beğenebilecekleri ürünleri zaman ve/veya paralarını boşa harcamadan satın almak isterler. Müşterilerine bu süreçte yardımcı olmak için birçok sanal şirket öneri sistemlerinden yararlanıp müşterilerine en-iyi-N önerileri sunmaktadır. En benzer varlıkları belirlemede kullanılan benzerlik ölçütleri en-iyi-N önerileri hizmetinin genel performansını etkileyebilir. İkili değerler üzerinde işlem yapan birçok benzerlik ölçütü bulunmasına rağmen bunların en-iyi-N önerilerinin doğruluğu ve çevrimiçi performansı üzerindeki etkisi detaylı biçimde çalışılmamıştır. yapıldı. Ayrıca en-iyi-N öneri algoritması en benzer kullanıcıların verisi öneri üretilirken kullanılacak şekilde değiştirildi. Değişen kontrol parametrelerinin performansa olan etkisi araştırıldı. Deneysel sonuçlar doğruluk ve performans açısından analiz edilerek bazı öneriler sunuldu

    18. Negative thermal expansion materials: technological key for control of thermal expansion

      OpenAIRE

      Koshi Takenaka

      2012-01-01

      Most materials expand upon heating. However, although rare, some materials contract upon heating. Such negative thermal expansion (NTE) materials have enormous industrial merit because they can control the thermal expansion of materials. Recent progress in materials research enables us to obtain materials exhibiting negative coefficients of linear thermal expansion over −30 ppm K−1. Such giant NTE is opening a new phase of control of thermal expansion in composites. Specifically examining pra...

    19. Unravelling the fundamentals of thermal and chemical expansion of BaCeO3 from first principles phonon calculations.

      Science.gov (United States)

      Løken, Andreas; Haugsrud, Reidar; Bjørheim, Tor S

      2016-11-16

      Differentiating chemical and thermal expansion is virtually impossible to achieve experimentally. While thermal expansion stems from a softening of the phonon spectra, chemical expansion depends on the chemical composition of the material. In the present contribution, we, for the first time, completely decouple thermal and chemical expansion through first principles phonon calculations on BaCeO 3 , providing new fundamental insights to lattice expansion. We assess the influence of defects on thermal expansion, and how this in turn affects the interpretation of chemical expansion and defect thermodynamics. The calculations reveal that the linear thermal expansion coefficient is lowered by the introduction of oxygen vacancies being 10.6 × 10 -6 K -1 at 300 K relative to 12.2 × 10 -6 K -1 for both the protonated and defect-free bulk lattice. We further demonstrate that the chemical expansion coefficient upon hydration varies with temperature, ranging from 0.070 to 0.115 per mole oxygen vacancy. Ultimately, we find that, due to differences in the thermal expansion coefficients under dry and wet conditions, the chemical expansion coefficients determined experimentally are grossly underestimated - around 55% lower in the case of 10 mol% acceptor doped BaCeO 3 . Lastly, we evaluate the effect of these volume changes on the vibrational thermodynamics.

    20. Application for approval of the Cold Lake Expansion Project: volume 2: environmental impact assessment: Part 1: biophysical and resource use assessment. Part 2: impact model descriptions

      International Nuclear Information System (INIS)

      Green, J.; Eccles, R.; Hegmann, G.; Morrison, L.; Salter, R.; van Egmond, T.; Vonk, P.; Ash, G.; Crowther, R.; Dance, T.; Edwards, W.; Veldman, W.

      1997-02-01

      An environmental assessment of the Cold Lake Expansion Project has been conducted to identify major issues of concern by public and government agencies, to determine means to eliminate or reduce those impacts, and to recommend any further efforts required to obtain missing information or monitor impacts. Volume 2 of the environmental impact assessment is divided into two parts. Part 1 (biophysical and resource use assessment) constitutes the primary environmental impact assessment document for the Cold Lake expansion project. It includes technical support documentation in regard to: (1) an assessment of noise impacts, (2) an assessment of greenhouse gas emissions, (3) a conceptual conservation and reclamation plan, (4) a historical resource impact assessment, and (5) a description of effects of oil spills on fish. Part 2 (impact model description) serves a reference document for part 1. It describes the approach taken in developing and assessing the impact models, discusses proposed methods for mitigation and management of residual impacts, and the recommended monitoring requirements for each of the major resource disciplines. The impact models describe the specific pathways through which impacts will occur as a result of interactions between project-related activities and important environmental components. 476 refs., 58 tabs., 23 figs

    1. Finite volume QCD at fixed topological charge

      OpenAIRE

      Aoki, Sinya; Fukaya, Hidenori; Hashimoto, Shoji; Onogi, Tetsuya

      2007-01-01

      In finite volume the partition function of QCD with a given $\\theta$ is a sum of different topological sectors with a weight primarily determined by the topological susceptibility. If a physical observable is evaluated only in a fixed topological sector, the result deviates from the true expectation value by an amount proportional to the inverse space-time volume 1/V. Using the saddle point expansion, we derive formulas to express the correction due to the fixed topological charge in terms of...

    2. High Statistics Analysis using Anisotropic Clover Lattices: (IV) The Volume Dependence of the Light Hadron Masses

      Energy Technology Data Exchange (ETDEWEB)

      Beane, S R; Detmold, W; Lin, H W; Luu, T C; Orginos, K; Parreno, A; Savage, M J; Torok, A; Walker-Loud, A

      2011-07-01

      The volume dependence of the octet baryon masses and relations among them are explored with Lattice QCD. Calculations are performed with nf = 2 + 1 clover fermion discretization in four lattice volumes, with spatial extent L ? 2.0, 2.5, 3.0 and 4.0 fm, with an anisotropic lattice spacing of b_s ? 0.123 fm in the spatial direction, and b_t = b_s/3.5 in the time direction, and at a pion mass of m_\\pi ? 390 MeV. The typical precision of the ground-state baryon mass determination is volume dependence of the masses, the Gell-Mann Okubo mass-relation, and of other mass combinations. A comparison with the predictions of heavy baryon chiral perturbation theory is performed in both the SU(2)L ? SU(2)R and SU(3)L ? SU(3)R expansions. Predictions of the three-flavor expansion for the hadron masses are found to describe the observed volume dependences reasonably well. Further, the ?N? axial coupling constant is extracted from the volume dependence of the nucleon mass in the two-flavor expansion, with only small modifications in the three-flavor expansion from the inclusion of kaons and eta's. At a given value of m?L, the finite-volume contributions to the nucleon mass are predicted to be significantly smaller at m_\\pi ? 140 MeV than at m_\\pi ? 390 MeV due to a coefficient that scales as ? m_\\pi^3. This is relevant for the design of future ensembles of lattice gauge-field configurations. Finally, the volume dependence of the pion and kaon masses are analyzed with two-flavor and three-flavor chiral perturbation theory.

    3. A vitamini ve anne çocuk sağlığı Derleme

      OpenAIRE

      Günlemez, Ayla; Atasay, Begüm; Arsan, Saadet

      2014-01-01

      A vitamini normal görmede hücre farklılaşmasında çoğalmasında ve epitelial bütünlüğün sağlanmasında kritik rol oynar Gelişmekte olan ülkelerde A vitamini eksikliği önemli ve önlenebilir halk sağlığı sorunlarından biridir Bu makalede dünyada ve Türkiye’de A vitamini eksikliği ve anne çocuk sağlığı üzerine etkileri tartışılmaktadır Anahtar Kelimeler: A vitamini anne sağlığı çocuk sağlığıSummaryVitamin A has a critical role in normal vision cell differantiation proliferation and maintanence of e...

    4. Anneden Allah'a: Bağlanma Teorisi ve İslâm'da Allah Tasavvuru

      OpenAIRE

      HAYTA, Akif

      2006-01-01

      John Bowlby tarafından geliştirilen bağlanma teorisi, yaşam boyu süren psikolojik bir sosyal ve kişilik gelişim teorisidir. Bağlanma teorisi bebek-çocuk ve bakıcısı arasındaki bağın gelişimi ve bu ilişkinin çeşitli fonksiyonlarının daha sonraki psikolojik gelişim üzerindeki etkilerine odaklanmıştır. Bağlanma teorisi bebek ve çocuk üzerine yapılan çalışmaları önemli derecede etkilemiş ve yığınla araştırmaya konu olmuştur. Aynı zamanda geniş bir alana yayılarak din psikolojisi araştırmalarında ...

    5. Following Surgically Assisted Rapid Palatal Expansion, Do Tooth-Borne or Bone-Borne Appliances Provide More Skeletal Expansion and Dental Expansion?

      Science.gov (United States)

      Hamedi-Sangsari, Adrien; Chinipardaz, Zahra; Carrasco, Lee

      2017-10-01

      The aim of this study was to compare outcome measurements of skeletal and dental expansion with bone-borne (BB) versus tooth-borne (TB) appliances after surgically assisted rapid palatal expansion (SARPE). This study was performed to provide quantitative measurements that will help the oral surgeon and orthodontist in selecting the appliance with, on average, the greatest amount of skeletal expansion and the least amount of dental expansion. A computerized database search was performed using PubMed, EBSCO, Cochrane, Scopus, Web of Science, and Google Scholar on publications in reputable oral surgery and orthodontic journals. A systematic review and meta-analysis was completed with the predictor variable of expansion appliance (TB vs BB) and outcome measurement of expansion (in millimeters). Of 487 articles retrieved from the 6 databases, 5 articles were included, 4 with cone-beam computed tomographic (CBCT) data and 1 with non-CBCT 3-dimensional cast data. There was a significant difference in skeletal expansion (standardized mean difference [SMD], 0.92; 95% confidence interval [CI], 0.54-1.30; P appliances. However, there was no significant difference in dental expansion (SMD, 0.05; 95% CI, -0.24 to 0.34; P = .03). According to the literature, to achieve more effective skeletal expansion and minimize dental expansion after SARPE, a BB appliance should be favored. Copyright © 2017 American Association of Oral and Maxillofacial Surgeons. Published by Elsevier Inc. All rights reserved.

    6. Psoriasisin Sistemik Tedavi Kilavuzu: Yöntem Seçimi ve Izlemle Ilgili Pratik Öneriler, Tartismali Konular

      Directory of Open Access Journals (Sweden)

      Tülin Ergun

      2007-03-01

      Full Text Available Psoriasis, sik görülen, çogu kez yasam boyunca süren ve genellikle tedaviyle yok edilemeyen bir hastaliktir. Bu durum, hastalarin yasam boyunca tedavi edilmesini ve özellikle siddetli hastaligi olan hastalarda, önemli yan etkileri olan ilaçlarin uzun süreli kullanilmasini gerektirir. Bu derlemenin amaci, dermatoji uzmanina, orta ve siddetli psoriasisi olan bir hastayla karsilastiginda hangi yöntemi seçmesi gerektigiyle ilgili rehberlik edebilmektir. Bu baglamda fototerapi, geleneksel ve biyolojik tedavi ajanlari, avantaj ve dezavantajlari, izlemde dikkat edilmesi gereken yönleriyle tartisilacaktir.

    7. Selected Issues of the Indicating Measurements in a Spark Ignition Engine with an Additional Expansion Process

      Directory of Open Access Journals (Sweden)

      Marcin Noga

      2017-03-01

      Full Text Available The paper presents the results of research on the turbocharged spark ignition engine with additional exhaust expansion in a separate cylinder, which is commonly known as the five-stroke engine. The research engine has been constructed based on the four cylinder engine in which two outer cylinders work as the fired cylinders, while two internally connected inner cylinders constitute the volume of the additional expansion process. The engine represents a powertrain realizing an ultra-expansion cycle. The purpose of the study was to find an effective additional expansion process in the five-stroke engine. Cylinder-pressure indicating measurements were carried out for one of the fired cylinders and the additional expansion cylinder. The study was performed for over 20 different points on the engine operation map. This allowed us to determine a dependence between the pressure indicated in the fired cylinders and in the additional expansion cylinders. A function of the mean pressure indicated in the additional expansion cylinder versus a brake mean effective pressure was also presented. This showed a load threshold from which the work of the cylinders of additional expansion produced benefits for the output of the experimental engine. The issues of mechanical efficiency and effective efficiency of this engine were also discussed.

    8. NİĞDE, ELMALI GÜNEYİ S-TİPİ BİYOTİT GRANİTOİDLERİ VE ANKLAVLARININ PETROLOJİSİ

      Directory of Open Access Journals (Sweden)

      Hüseyin KURT

      2006-02-01

      Full Text Available Biyotit granitoidler başlıca kuvars, biyotit, plajiyoklas, K-feldispat, muskovit nadiren amfibol içerirler. Tali bileşen olarak apatit, zirkon, allanit ve ikincil olarak klorit ve serisit içerirler. Anklavlar başlıca plajiyoklas, amfibol, ojit, biyotit, tali bileşen olarak sfen, zirkon ve ikincil olarak kalsit ve epidot minerallerini içerirler. Metalumino bileşimli anklav içeren, granitoidler S-tip granitlere ait kimyasal ve mineralojik özellikler gösterirler: peralumino (A/CNK oranı >1.15 bileşim ve muskovit minerali. Granitoidler büyük iyonlu litofil element (BİLE ve hafif nadir toprak elementlerce (HNTE zenginleşme ve ağır nadir toprak elementlerce fakirleşme (ANTE sunarlar. Bu durum granitoidlerin kabuk ergimesiyle oluştuğunu, negatif Eu anomalisi ve büyük iyon litofil elementlerince zenginlik göstermeleri plajiyoklasların fraksiyonlaşmada etkisini göstermektedir. Anklavlarda büyük iyonlu litofil element (BİLE zenginleşmesi, yüksek alan enerjili elementlerde (YAEE fakirleşme, nadir toprak element (NTE dağılımlarında yataya yakın desen vermeleri ve negatif Eu anomalisi göstermeleri, anklavların litosferik mantodan kaynaklandığını ve hornblend, plajiyoklasların fraksiyonlaşmada etkisini göstermektedir. Arazi, petrografik ve jeokimyasal verilere dayanarak, volkanik yay özellikli granitlerin mafik magmanın kabuğa sokulması ve muhtemelen kabuk kalınlaşması ile oluştuğu ve mafik magma ile fiziksel olarak karışarak anklavları oluşturduğu ileri sürülmüştür.

    9. ADRENOMEDULLİN VE DİYABET Adrenomedullin And Diabetes

      OpenAIRE

      BAYRAM, Zeliha; S. ÖZDEM, Sadi

      2018-01-01

      ÖZETAdrenomedullin (ADM) son dönemde keşfedilen, çok fonksiyonu olan bir peptiddir. Karakteristiketkileri arasında vazodilatör etkisi ve hipotansif özellikleri yer almaktadır. Farklı organlardayaygın bir üretim ve ekspresyonunun olduğu düşünüldüğünde ADM, çeşitli biyolojik sistemlerdeotokrin, endokrin ya da parakrin bir mediyatör olarak rol oynayabilir. Plazma ADM düzeylerininçeşitli hastalıklarda artması, ADM’nin hastalık durumlarında olası bir modülatör rolüne işaretetmektedir. Kardiyovaskü...

    10. Competition between reaction-induced expansion and creep compaction during gypsum formation: Experimental and numerical investigation

      Science.gov (United States)

      Skarbek, R. M.; Savage, H. M.; Spiegelman, M. W.; Kelemen, P. B.; Yancopoulos, D.

      2017-12-01

      Deformation and cracking caused by reaction-driven volume increase is an important process in many geological settings, however the conditions controlling these processes are poorly understood. The interaction of rocks with reactive fluids can change permeability and reactive surface area, leading to a large variety of feedbacks. Gypsum is an ideal material to study these processes. It forms rapidly at room temperature via bassanite hydration, and is commonly used as an analogue for rocks in high-temperature, high-pressure conditions. We conducted uniaxial strain experiments to study the effects of applied axial load on deformation and fluid flow during the formation of gypsum from bassanite. While hydration of bassanite to gypsum involves a solid volume increase, gypsum exhibits significant creep compaction when in contact with water. These two volume changing processes occur simultaneously during fluid flow through bassanite. We cold-pressed bassanite powder to form cylinders 2.5 cm in height and 1.2 cm in diameter. Samples were compressed with a static axial load of 0.01 to 4 MPa. Water infiltrated initially unsaturated samples through the bottom face and the height of the samples was recorded as a measure of the total volume change. We also performed experiments on pure gypsum samples to constrain the amount of creep observed in tests on bassanite hydration. At axial loads 1 MPa, creep in the gypsum dominates and samples exhibit monotonic compaction. At intermediate loads, samples exhibit alternating phases of compaction and expansion due to the interplay of the two volume changing processes. We observed a change from net compaction to net expansion at an axial load of 0.250 MPa. We explain this behavior with a simple model that predicts the strain evolution, but does not take fluid flow into account. We also implement a 1D poro-visco-elastic model of the imbibition process that includes the reaction and gypsum creep. We use the results of these models, with

    11. Kapak ve İçindekiler

      Directory of Open Access Journals (Sweden)

      Kapak ve İçindekiler

      2016-04-01

      Full Text Available Bu dergi, aşağıda listelenen veri tabanları tarafından taranmaktadır / This journal is indexed by the following abstracting and indexing databasesBASE, CAB Abstracts, CAS (Chemical Abstracts Service, DOAJ, EBSCO Discovery Service (EDS, Google Scholar, JournalTOCs, OAJI, ResearchBib, Ulakbim TR Dizin (Mühendislik ve Temel Bilimler, WorldCat (OCLC, Zentralblatt MATH

    12. Kapak ve İçindekiler

      Directory of Open Access Journals (Sweden)

      Kapak İçindekiler

      2016-08-01

      Full Text Available Bu dergi, aşağıda listelenen veri tabanları tarafından taranmaktadır / This journal is indexed by the following abstracting and indexing databasesBASE, CAB Abstracts, CAS (Chemical Abstracts Service, CiteFactor, DOAJ, DRJI, EBSCO Discovery Service (EDS, Google Scholar, JournalTOCs, OAJI, ResearchBib, Ulakbim TR Dizin (Mühendislik ve Temel Bilimler, WorldCat (OCLC, Zentralblatt MATH

    13. Farklı Durum Çeşitlerinden Mahalli ve Laboratuvar Koşullarında Yapılmış Bulguların Bazı Vitamin ve Mineral İçerikleri

      Directory of Open Access Journals (Sweden)

      Berrin Özkaya

      2015-02-01

      Full Text Available Araştırmada 5 farklı durum buğdayının, bunlardan mahalli ve laboratuvar koşullarında yapılan bulguların bazı kimyasal özellikleri ile tiamin, riboflavin ve mineral içerikleri karşılaştırılmıştır. Buğdayların yapımı sırasında buğdayların tiamin, özellikle de riboflavin miktarları azalmıştır. Mahalli koşullarda yapılan bulgurların tiamin ve riboflavin miktarları laboratuvarda yapılanlara kıyasla biraz düşük çıkmıştır. Bulgurların mineral içerikleri (Fe, Cu, Zn, Mn, Ca ve Mg miktarları yapıldıktan buğdaylara kıyasla daha düşük çıkmış, mahalli ve laboratuvar koşullarında yapılan bulgurların mineral madde miktarlarında önemli bir fark görülmemiştir.

    14. Pressure of a partially ionized hydrogen gas: numerical results from exact low temperature expansions

      Energy Technology Data Exchange (ETDEWEB)

      Alastuey, A. [Laboratoire de Physique, ENS Lyon, CNRS, Lyon (France); Ballenegger, V. [Institut UTINAM, Universite de Franche-Comte, CNRS, Besancon (France)

      2010-01-15

      We consider a partially ionized hydrogen gas at low densities, where it reduces almost to an ideal mixture made with hydrogen atoms in their ground-state, ionized protons and ionized electrons. By performing systematic low-temperature expansions within the physical picture, in which the system is described as a quantum electron-proton plasma interacting via the Coulomb potential, exact formulae for the first.ve leading corrections to the ideal Saha equation of state have been derived[A. Alastuey, V. Ballenegger et al., J. Stat. Phys. 130, 1119 (2008)]. Those corrections account for all effects of interactions and thermal excitations up to order exp(E{sub H} /kT) included, where E{sub H} {approx_equal} -13.6 eV is the ground state energy of the hydrogen atom. Among the.ve leading corrections, three are easy to evaluate, while the remaining ones involve suitably truncated internal partition functions of H{sub 2} molecules and H{sup -} and H{sub 2}{sup +} ions, for which no analytical formulae are available in closed form. We estimate those partitions functions at.nite temperature via a simple phenomenology based on known values of rotational and vibrational energies. This allows us to compute numerically the leading deviations to the Saha pressure along several isotherms and isochores. Our values are compared with those of the OPAL tables (for pure hydrogen) calculated within the ACTEX method (copyright 2010 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim) (orig.)

    15. Bıldırcın ve Ördek Yumurtalarında Maya-Küf ve Total Bakteri Açısından İncelenmesi

      Directory of Open Access Journals (Sweden)

      Işın Var

      2015-02-01

      Full Text Available Bıldırcın yumurtası, besin değeri yönünden tavuk yumurtasından oransal olarak daha zengin kabul edilmektedir. Daha çok salata, pasta, mayonez vb. yapımında yaygın olarak kullanılan ördek yumurtası (Pekin ördeği tavuk yumurtasına göre daha büyük olup, ağırlıkları 70-90 g arasında değişmektedir. Bıldırcın yumurtası son yıllarda özellikle küçük çocuk ve yaşlı beslenmesinde önem kazanmıştır. Bunun yanısıra bazı hastalıkların tedavisi amacıyla da halk arasında oldukça yaygın kullanılmaktadır. Özellikle çiğ olarak tüketilen bıldırcın yumurtaları zaman zaman içerdikleri patojen mikroorganizmalarla tehlikeli olabilmektedirler. Bu çalışmada bıldırcın ve ördek yumurtalarında maya-küf ve total bakteri aranmıştır. Bıldırcın ve ördek yumurtalarının özellikle kabuğunda hem total bakteri hem de maya-küf bulunmuştur. Bıldırcın yumurtasının akı ve sarısında ise zaman zaman kontaminasyonla karşılaşılmıştır.

    16. The Digital Exhibition and Keyimage Ontology / Dijital Sergiler ve Anahtar Resim Ontolojisi

      Directory of Open Access Journals (Sweden)

      Mícheál Mac an Airchinnigh

      2008-04-01

      Full Text Available [English abstract]The Age of Image predates and is currently contemporaneous with the Information Age. In our times the explosive expansion of Web 2.0 Social Space, typified by the phenomena of De.licio.us, Flickr, MySpace, YouTube…, and the concomitant emergence of folksonomy, present interesting challenges in the management of this information. One key process by which to accomplish this in Social Space, is the wedding of folksonomy (of the people with ontology (of the machine. Such a wedding must necessarily be conducted in the shared physicality of the word, of language. In this respect, WordNet together with OWL, play the role of matchmaker. But the same Social Space also provides an opportunity for natural folksonomical tagging by digiFoto (keyimage. The research harness for experimental keyimage tagging consists of Flickr as the main (digiFoto image Social Space testbed and De.licio.us as the auxillary outreach secondary Social Space. Protégé Editor with OWL-DL provides the support for the bridge from keyimage to the formal ontology. The primary end user application domain is the keyimage tagging of paintings in an online art gallery.[Turkish abstract]Görüntü Çağı, Bilgi Çağından önce gelir ve günümüzde Bilgi Çağıyla çağdaştır. De.licio.us, Flickr, MySpace, YouTube. . . gibi olgularla örneklenen Web 2.0 Sosyal Uzayının tahminlerin ötesinde büyümesi ve bununla birlikte ortaya çıkan etiketleme bilgi yönetiminde ilginç gelişmelere sahne olmaktadır. Sosyal Uzayda bilgi yönetimini başarmak (insanlar tarafından gerçekleştirilen etiketleme ve (makineler tarafından gerçekleştirilen ontolojinin birleştirilmesini gerektirmektedir. Böyle bir birleştirme mutlaka sözün ve dilin ortak fizikselliğiyle gerçekleştirilmelidir. Bu hususta Web Ontoloji Dili (OWL ile WordNet çöpçatan rolü oynarlar. Öte yandan aynı Sosyal Uzay dijiFoto (anahtar resimle doğal folksonomik işaretleme yapmak için de bir

    17. TÜRKİYE’DE PETROL TALEBİNİN FİYAT VE GELİR ESNEKLİKLERİ: ARDL SINIR TESTİ VE NEDENSELLİK ANALİZİ

      Directory of Open Access Journals (Sweden)

      Muhammed Şehid GÖRÜŞ

      2016-03-01

      Full Text Available ÖZ: Bu çalışmanın temel amacı, 1970-2013 dönemleri arasında Türkiye’nin petrol talebinin fiyat ve gelir esnekliklerini tahmin etmek ve petrol fiyatı, petrol talebi ve gelir düzeyi arasındaki nedensellik ilişkisinin yönünü tespit etmektir. Çalışmada tahmin yöntemleri olarak ARDL Sınır Testi yaklaşımı ve Toda-Yamamoto (1995 Granger Nedensellik Testi kullanılmıştır. Yapılan analiz sonucunda değişkenler arasında bir eşbütünleşme ilişkisinin mevcut olduğu gözlemlenmiştir Elde edilen sonuçlara göre, uzun dönemde petrol talebinin fiyat esnekliği -0,17; gelir esnekliği ise 0,51 olarak hesaplanmıştır. Diğer yandan, kısa dönemdeki fiyat esnekliği ise -0,08; gelir esnekliği ise 0,59 olarak tahmin edilmiştir. Elde edilen ampirik sonuçlara göre, petrol talebinin fiyat ve gelir esneklikleri hem uzun dönemde hem de kısa dönemde inelastiktir. Nedensellik Testi sonuçlarına göre ise petrol fiyatından petrol talebine doğru tek yönlü bir nedensellik ilişkisi tespit edilmiştir. Bu sonuçlardan Türkiye’de petrol fiyatı ve gelir düzeyinin petrol talebi üzerinde kısa ve uzun dönemde güçlü bir etkisinin olmadığı, bunun temel nedeninin ise petrolün zorunlu mallar arasında yer almasından kaynaklandığı söylenebilir. ABSTRACT: The primary objective of this paper is estimating price elasticity and income elasticity of oil demand, and causality relationship between variables with respect to Turkish economy for the period of 1970 and 2013. In the study, ARDL Bound Test approach and Toda-Yamamoto (1995 Granger Causality Test are employed as an estimation method. According to bound test analysis, a cointegration relationship is found between variables. Empirical findings show that long-run price and income elasticity of oil demand in Turkey is -0.17 and 0.51 respectively. On the other hand, short-run price and income elasticity of oil demand estimated as -0.08 and 0.59 respectively

    18. WOMEN AND THE SOCIO- PYSCHOLOGIC CHARACTERISTICS OF WOMAN IN IDIOMS AND PROVERB ABSTRACT ATASÖZÜ VE DEYİMLERDE KADIN VE KADININ SOSYO-PSİKOLOJİK ÖZELLİKLERİ

      Directory of Open Access Journals (Sweden)

      Zekerya BATUR

      2011-09-01

      Full Text Available Proverbs and idioms are seen as a data source shedding light on a society's social structure. These data sources reveal social relations, daily life and the cultural context. Proverbs and idioms are thought to hold an important place to understand the society’s views towards individual's attitude and behavior from the past to present. This study made by general scanning model. Proverbs and idioms were scanned and words, which included women, identified. After that, meaning and mission of woman in bloc words analyzed. In conclusion, women showed sometimes source of fidelity, sometimes dishonored affection, sometimes hostility and sometimes antagonism and repulsion in bloc words. Atasözü ve deyimler, bir toplumun sosyal yapısına ışık tutan birer veri kaynağı olarak görülmektedir. Bu veri kaynakları sosyal ilişkileri, günlük yaşamı ve kültürel yapıyı gözler önüne sermektedir. Toplumun geçmişten günümüze bireyin tutum ve davranışlarına ilişkin bakışını anlamak için atasözü ve deyimlerin önemli bir yer tuttuğu düşünülmektedir. Bu çalışma genel tarama modelinde yapılmıştır. Çalışmada atasözleri ve deyimler taranarak kadın kavramının geçtiği sözler tespit edilmiştir. Daha sonra kadının kalıp sözlerdeki anlamı ve görevi sözlerden hareketle incelenmiştir. Sonuçta kalıplaşmış sözlerde kadın, bazen sadakatin bazen karşılıksız sevginin bazen düşmanlığın bazen de kin ve nefretin kaynağı olarak gösterilmiştir.

    19. KARAGÖZ VE HACİVAT: BAŞKALDIRI VE İTAATİN YANSIMALARI / KARAGÖZ AND HACİVAT: PROJECTIONS OF SUBVERSION AND CONFORMANCE

      Directory of Open Access Journals (Sweden)

      ONUR AYKAÇ

      2016-12-01

      Full Text Available Bu yazı, James Smith’in Asian Theatre Journal’da 2004 yılında yayımladığı “Karagöz and Hacivat: Projections of Subversion and Conformance” adlı makalesinin tercümesidir. Smith, İslam dünyasında tiyatro temsillerinin tarihini kısaca anlattıktan sonra, sözü Türklerde karagöz, Yunanlarda karagiozis adıyla bilinen gölge oyunlarına getirir. Bu oyunlara dair kısa tanıtıcı bilgiler verdikten sonra, Peter Burke’ün Popular Culture in Early Modern Europe (Erken Modern Avrupa’da Popüler Kültür adlı eserinde hemen her karnavalda görüldüğünü söylediği “yemek, cinsellik ve şiddet” unsurlarına karagöz oyunlarından örnekler verir. Akabinde, gölge oyununu Mikhail Bakhtin’in dinsel eğlence teorisi çerçevesinde inceler. Bilhassa, sözü edilen teoride yer alan “bir maskaraya taç giydirilip kral yapılması ve karnavalın sonunda sahte kralın tahttan indirilmesi hadisesi” ile “Hacivat tarafından önemli bir mevkie getirildikten sonra çevresindekileri alt etmeye çalışan ve sonunda bütün gücü elinden alınan Karagöz’ün durumu” arasında ciddi bir benzerlik olduğu kanısına varır. Son aşamada, gölge oyununun, ezilen toplum kitlesinin özkimliğini yeniden oluşturmadaki rolüne değinerek, meseleyi Türk ve Yunan halkları üzerinden örneklendirir. Bu yazı, hem Batılı eğlence kuramlarının karagöz ve karagiozis oyunlarına uygulanmış olması, hem de bu oyunların yeni bir özkimlik oluşturmada nasıl bir görev üstlendiğini göstermesi bakımından önemlidir.

    20. Gabriel Tarde ve Medya-Toplum İlişkisini Yeniden Keşfetmek

      Directory of Open Access Journals (Sweden)

      Murat Sadullah Çebi

      2013-09-01

      Full Text Available ÖzBu çalışmanın amacı, Fransız sosyolog Gabriel Tarde’ın geliştirdiği ‘kamusal alan modeli’ üzerinden medya ve toplum ilişkisini yeniden keşfetmek, anlamak ve açıklamaktır. Tarde’ın kamusal alan modeli, karşılıklı etkileşen dört unsurdan oluşur: Basın, sohbet, kamuoyu, eylem. Tarde, modern toplumda basına önemli işlevler yükler. Tarde’a göre basın; bilgili, eleştirel ve rasyonel bir kamunun ortaya çıkmasını ve gelişmesini sağlamıştır. İkinci olarak; kahvehane ve salonlarda cereyan eden bir kamusal tartışma ve müzakere biçimine, yani sohbetlere zemin oluşturmuştur. Üçüncü olarak; kamuoyunu dillendirmiş ve oluşturmuştur. Dördüncü olarak; bireylerin sosyal, politik ve ekonomik süreçlerdeki seçim ve kararlarını etkilemiştir. Nihayetinde, zihinlerde hayalî bir kurgu olarak millet ve milliyet fikrini oluşturmuştur. Araştırmada; Tarde’ın kamusal alan modelinin, iletişim biliminde ‘iki aşamalı iletişim akışı modeli’ olarak bilinen ‘sınırlı medya etkileri modeli’nin ilk örneklerinden biri olduğu sonucuna ulaşılacaktır. AbstractThe purpose of this study is to rediscover, to understand and to interpret, relationships between the mass media and society through public sphere model developed by French sociologist Gabriel Tarde. Tarde’s public sphere model consists of four elements: Press, conversation, public opinion and action. Tarde attributed important roles to press in modern society. Firstly, according to Tarde press provided to emerge and to develop of a knowledgeable, critical and rational public. Secondly, it formed a basis for public discussions and deliberations, in other words for conversations that took place in coffee houses and saloons. Thirdly, it expressed and created public opinion. Fourthly, it determined choices and decisions of people in social, economic and political processes. Lastly, it created the idea of nation and nationality

    1. FIJI Macro 3D ART VeSElecT: 3D Automated Reconstruction Tool for Vesicle Structures of Electron Tomograms.

      Directory of Open Access Journals (Sweden)

      Kristin Verena Kaltdorf

      2017-01-01

      Full Text Available Automatic image reconstruction is critical to cope with steadily increasing data from advanced microscopy. We describe here the Fiji macro 3D ART VeSElecT which we developed to study synaptic vesicles in electron tomograms. We apply this tool to quantify vesicle properties (i in embryonic Danio rerio 4 and 8 days past fertilization (dpf and (ii to compare Caenorhabditis elegans N2 neuromuscular junctions (NMJ wild-type and its septin mutant (unc-59(e261. We demonstrate development-specific and mutant-specific changes in synaptic vesicle pools in both models. We confirm the functionality of our macro by applying our 3D ART VeSElecT on zebrafish NMJ showing smaller vesicles in 8 dpf embryos then 4 dpf, which was validated by manual reconstruction of the vesicle pool. Furthermore, we analyze the impact of C. elegans septin mutant unc-59(e261 on vesicle pool formation and vesicle size. Automated vesicle registration and characterization was implemented in Fiji as two macros (registration and measurement. This flexible arrangement allows in particular reducing false positives by an optional manual revision step. Preprocessing and contrast enhancement work on image-stacks of 1nm/pixel in x and y direction. Semi-automated cell selection was integrated. 3D ART VeSElecT removes interfering components, detects vesicles by 3D segmentation and calculates vesicle volume and diameter (spherical approximation, inner/outer diameter. Results are collected in color using the RoiManager plugin including the possibility of manual removal of non-matching confounder vesicles. Detailed evaluation considered performance (detected vesicles and specificity (true vesicles as well as precision and recall. We furthermore show gain in segmentation and morphological filtering compared to learning based methods and a large time gain compared to manual segmentation. 3D ART VeSElecT shows small error rates and its speed gain can be up to 68 times faster in comparison to manual

    2. Portsmouth Gaseous Diffusion Plant expansion: final environmental statement. Volume 2. Appendices

      International Nuclear Information System (INIS)

      1977-09-01

      Volume 2 is comprised of appendices: Portsmouth Gaseous Diffusion Plant Existing Facilities; Ecology; Civic Involvement; Social Analysis; Population Projections; Toxicity of Air Pollutants to Biota at Portsmouth Gaseous Diffusion Plant; and Assessment of Noise Effects of an Add-On to the Portsmouth Gaseous Diffusion Plant

    3. Tutum, Değer Ve Özyeterlik Değişkenlerinin TIMSS-1999 ve TIMSS-2007 Sınavlarında Öğrencilerin Matematik Başarılarını Yordama Düzeyleri

      OpenAIRE

      DOĞAN, Nuri; BARIŞ, Fulya

      2010-01-01

      Bu araştırmada TIMSS–1999 ve TIMSS–2007 uygulamalarına giren Türk öğrencilerin bazı duyuşsalözelliklerinin matematik puanlarını yordama düzeyi incelenmiştir. TIMSS anketlerinde bulunan ve duyuşsalboyutları ölçen; tutum, değer ve öz-yeterlik puanları bağımsız değişken ve öğrencilerin matematik başarıpuanları bağımlı değişken olarak ele alınmıştır. Verilerin analizinde standart çoklu regresyon tekniğindenyararlanılmıştır. Analizler sonucunda, TIMSS-1999 ve TIMSS-2007 sınavlarında öğrencilerin m...

    4. Stress and phase changes in a low-thermal-expansion Al-3at.%Ge alloy film on oxidized silicon wafers

      International Nuclear Information System (INIS)

      Tu, K.N.; Rodbell, K.P.; Herd, S.R.; Mikalsen, D.J.

      1993-01-01

      The alloy of Al-3at.%Ge has been found to have a low thermal expansion and contraction in the temperature range of room temperature to 400 C. The reason for the low thermal contraction (or expansion) is the precipitation (or dissolution) of Ge in the alloy. The Ge precipitates have a diamond structure in which each Ge atom occupies a much larger atomic volume than a Ge atom dissolved substitutionally in Al. The volume difference compensates for the effect of thermal expansion and contraction with changing temperature which in turn reduces the thermal stress due to thermal mismatch. The technique of wafer bending was used to determine the stress of the alloy film on oxidized silicon wafers upon thermal cycling; indeed, it is much lower than that of pure Al on identical wafers. The morphology of precipitation and dissolution of Ge in Al has been studied by transmission and scanning electron microscopy. It is found that the precipitation follows a discontinuous mode and occurs predominantly along grain boundaries. In dissolving the Ge precipitates into Al, voids are left behind because of the volume difference. It is proposed that this may explain the enhancement of nucleation of voids in the alloy film upon thermal cycling. (orig.)

    5. Taxa de mortalidade por acidentes de trâsito e frota de veículos

      Directory of Open Access Journals (Sweden)

      Samuel Kilsztajn

      2001-06-01

      Full Text Available OBJETIVO: A taxa de mortalidade específica por acidentes de trânsito de veículos a motor é usualmente utilizada para efeito das políticas de saúde pública. Para mensurar o grau de violência no trânsito, foi realizado estudo com o objetivo de analisar o número de óbitos por acidentes de trânsito por veículo a motor. MÉTODOS: Com base nos dados sobre frota de veículos, população e óbitos por acidente de trânsito, publicados no Statiscal Yearbook (1999, Demografic Yearbook (1997, Denatran (1999, Ministério da Saúde (2000 e Fundação IBGE (2000, foram estudados 61 países e 51 localidades brasileiras.A taxa de mortalidade específica foi decomposta em número de veículos por habitante e número de óbitos por veículo. Numa primeira aproximação, cada uma das amostras (internacional e brasileira foi subdividida em três grupos, de acordo com o número de veículos por habitante, para estudo da relação entre os três índices. Para testar a significância dessa relação, foi estimada uma função de regressão log-linear. RESULTADOS: Os resultados para as estimativas internacionais, assim como as do Brasil, demonstraram que, quanto maior o número de veículos por habitante, menor o número de óbitos por acidentes de trânsito por veículo, tendo-se elasticidade da ordem de -1,067, para as estimativas internacionais, e de -0,515, para as do Brasil. CONCLUSÕES: Para uma política de prevenção dos acidentes de trânsito, os resultados encontrados indicam a necessidade de estudar os fatores que possam explicar o maior número de óbitos por veículo nas regiões com menor número de veículos por habitante.

    6. Bibliometrický seminář ve Vídni

      Czech Academy of Sciences Publication Activity Database

      Laiblová Kadlecová, Ivana

      -, č. 2 (2012) E-ISSN 1805-2800 Keywords : bibliography databases * bibliometrics * citation indexes * Web of Science * Austria http://www.lib.cas.cz/casopis-informace/bibliometricky-seminar-ve-vidni/

    7. Hemoglobin mass and intravascular volume kinetics during and after exposure to 3,454-m altitude

      DEFF Research Database (Denmark)

      Siebenmann, C; Cathomen, A; Hug, M

      2015-01-01

      High altitude (HA) exposure facilitates a rapid contraction of plasma volume (PV) and a slower occurring expansion of hemoglobin mass (Hbmass). The kinetics of the Hbmass expansion has never been examined by multiple repeated measurements, and this was our primary study aim. The second aim...

    8. GELECEĞİN MALİYETLERİNİN KONTROLÜNDE YENİ BİR YAKLAŞIM: HEDEF VE KAIZEN MALİYETLEME

      Directory of Open Access Journals (Sweden)

      ZEYNEP TÜRK

      2013-05-01

      Full Text Available Firmalar tarafından modern üretim teknolojilerinin kullanılması yeni maliyet ve yönetim muhasebesi yöntemlerinin geliştirilmesine ve uygulanmasına neden olmuştur. Hedef ve kaizen maliyetleme bu yeni sistemlerin örneklerindendir. Japon elektronik ve araç üreticileri hedef ve kaizen maliyetlemeyi yoğun bir şekilde kullanmışlardır. Hedef ve kaizen maliyetleme, firmalara bugünün dizaynı ile geleceğin maliyetlerinin düşürülmesinde ve kontrol edilmesinde yardımcı olmaktadır. Çalışmamızda, söz konusu maliyet sistemleri ayrıntıları ile incelenecektir.

    9. Physiological mechanisms of dyspnea during exercise with external thoracic restriction: Role of increased neural respiratory drive

      Science.gov (United States)

      Mendonca, Cassandra T.; Schaeffer, Michele R.; Riley, Patrick

      2013-01-01

      We tested the hypothesis that neuromechanical uncoupling of the respiratory system forms the mechanistic basis of dyspnea during exercise in the setting of “abnormal” restrictive constraints on ventilation (VE). To this end, we examined the effect of chest wall strapping (CWS) sufficient to mimic a “mild” restrictive lung deficit on the interrelationships between VE, breathing pattern, dynamic operating lung volumes, esophageal electrode-balloon catheter-derived measures of the diaphragm electromyogram (EMGdi) and the transdiaphragmatic pressure time product (PTPdi), and sensory intensity and unpleasantness ratings of dyspnea during exercise. Twenty healthy men aged 25.7 ± 1.1 years (means ± SE) completed symptom-limited incremental cycle exercise tests under two randomized conditions: unrestricted control and CWS to reduce vital capacity (VC) by 21.6 ± 0.5%. Compared with control, exercise with CWS was associated with 1) an exaggerated EMGdi and PTPdi response; 2) no change in the relationship between EMGdi and each of tidal volume (expressed as a percentage of VC), inspiratory reserve volume, and PTPdi, thus indicating relative preservation of neuromechanical coupling; 3) increased sensory intensity and unpleasantness ratings of dyspnea; and 4) no change in the relationship between increasing EMGdi and each of the intensity and unpleasantness of dyspnea. In conclusion, the increased intensity and unpleasantness of dyspnea during exercise with CWS could not be readily explained by increased neuromechanical uncoupling but likely reflected the awareness of increased neural respiratory drive (EMGdi) needed to achieve any given VE during exercise in the setting of “abnormal” restrictive constraints on tidal volume expansion. PMID:24356524

    10. The impact of maternal plasma volume expansion and antihypertensive treatment with intravenous dihydralazine on fetal and maternal hemodynamics during pre-eclampsia: a clinical, echo-Doppler and viscometric study.

      Science.gov (United States)

      Boito, S M E; Struijk, P C; Pop, G A M; Visser, W; Steegers, E A P; Wladimiroff, J W

      2004-04-01

      To establish the effects of plasma volume expansion (PVE) followed by intravenous dihydralazine (DH) administration on maternal whole blood viscosity (WBV) and hematocrit, uteroplacental and fetoplacental downstream impedance and umbilical venous (UV) volume flow in pre-eclampsia. In 13 pre-eclamptic women maternal and fetal hemodynamics were established by means of combined measurement of maternal arterial blood pressure (BP), WBV, hematocrit and uterine artery (UtA) resistance index (RI) in addition to umbilical artery (UA) pulsatility index (PI) and UV volume flow obtained from UV vessel area and UV time-averaged flow velocity. In each woman all parameters were measured four times at baseline, after PVE, after DH and 24 h after the start of treatment. Maternal diastolic BP, hematocrit and WBV display a significant reduction after PVE. In the fetus UA PI decreases significantly whereas a significant increase in UV cross-sectional area was detected. After maternal DH administration, arterial systolic and diastolic BP and UA PI show a significant decrease compared with the measurements following PVE. At 24 h, only maternal systolic and diastolic BP display a significant further decrease. No significant changes were established for the UtA RI, UV time-averaged velocity and UV volume flow during the entire study period. During pre-eclampsia, maternal PVE followed by DH administration results in a significant reduction in maternal diastolic BP, maternal hematocrit and WBV. Maternal PVE is associated with a significant increase in UV cross-sectional area and a non-significant rise of 11% in UV volume flow. Maternal DH administration does not result in any change in UV cross-sectional area. However, UA PI decreases significantly after both PVE and DH treatment. Copyright 2004 ISUOG.

    11. Methods of ex vivo expansion of human cord blood cells: challenges, successes and clinical implications.

      Science.gov (United States)

      Baron, Frédéric; Ruggeri, Annalisa; Nagler, Arnon

      2016-03-01

      More than 40,000 unrelated cord blood transplantations (UCBT) have been performed worldwide as treatment for patients with malignant or non-malignant life threatening hematologic disorders. However, low absolute numbers of hematopoietic stem and progenitor cells (HSPCs) within a single cord blood unit has remained a limiting factor for this transplantation modality, particularly in adult recipients. Further, because UCB contains low numbers of mostly naïve T cells, immune recovery after UCBT is slow, predisposing patients to severe infections. Other causes of UCBT failure has included graft-versus-host disease (GVHD) and relapse of the underlying disease. In this article, we first review the current landscape of cord blood engineering aimed at improving engraftment. This includes approaches of UCB-HSPCs expansion and methods aimed at improving UCB-HSCPs homing. We then discuss recent approaches of cord blood engineering developed to prevent infection [generation of multivirus-specific cytotoxic T cells (VSTs) from UCB], relapse [transduction of UCB-T cells with tumor-specific chimeric receptor antigens (CARs)] and GVHD (expansion of regulatory T cells from UCB). Although many of these techniques of UCB engineering remain currently technically challenging and expensive, they are likely to revolutionize the field of UCBT in the next decades.

    12. JEOTERMAL ALANLARIN JEOFİZİK YÖNTEMLERLE ARAŞTIRILMASI VE UYGULAMA ÖRNEKLERİ

      Directory of Open Access Journals (Sweden)

      Züheyr KAMACI

      1997-01-01

      Full Text Available Dünyada yenilenebilen enerji kaynaklarından jeotermal enerjinin elektrik üretimi ve merkezi ısıtmada kullanıldığı düşünülürse, günümüzde yıllık 77 milyon varillik petrol eşdeğer tasarruf sağlar. Jeofizik arama yöntemleri, jeotermal alanların hem araştırılmasında hem de geliştirilmesinde ve doğrudan gözlenmesinde önemli rol oynamaktadır. Sıcaklık anomalilerini doğrudan doğruya gösteren ve mekanik sondaj yerlerinin belirlenmesinde en etkili yöntemler, termal ve jeoelektrik yöntemlerdir. Ancak söz konusu jeotermal alanların araştırılmasında anılan jeofizik arama yöntemlerinden başka Gravite, Manyetik, Sismik, Radyometrik, Kuyu Jeofiziği ve Kuyu Logu ile jeotomografinin birlikte kullanılması halinde daha iyi sonuçlar ortaya çıkabilmektedir. Buradan hareketle, bu makalede jeofizik arama yöntemleri kullanılarak jeotermal alanların saptanması ile ilgili dünyadan ve ülkemizden iki uygulama örneği verilmiştir. Bunlardan Uşak-Banaz jeotermal alanında jeoelektrik yöntemler kullanılarak yapılan çalışma sonucunda 55 °C'de artezyen yapan sıcak su bulunmuştur.

    13. KARANFİLLİÇAY DERESİ SUYUNUN FİZİKOKİMYASAL VE MİKROBİYOLOJİK PARAMETRELERİNİN MEVSİMSEL DEĞİŞİMİ VE AKUAKÜLTÜR AÇISINDAN DEĞERLENDİRİLMESİ

      OpenAIRE

      Bulut, Cafer; Akçimen, Ufuk; Uysal, Kazım; Küçükkara, Ramazan; Savaşer, Soner

      2018-01-01

      Bu çalışmada; Denizli ve Muğla sınırları içindebulunan Karanfilliçay Deresi üzerinde memba ve dere sonu olarak seçilen ikiistasyonda (1. istasyon: 36o 52ı40.58ıı N ve 29o 11ı51.16ıı E;  2.istasyon: 36o 58 ı 58.69ııN - 29o12 ı 22.36 ıı E) fizikokimyasalve mikrobiyolojik parametreler Ocak 2007’den Ocak 2008’e kadar aylık ölçülmüşve elde edilen bulgular akuakültür açısından değerlendirilmiştir. İki istasyonarasında yaklaşık 109 ton/yıl porsiyonluk ve 605.000 adet/yıl yavru alabalıkürete...

    14. Statistična ocena protipožarne varnosti večstanovanjskih zgradb v Sloveniji

      Directory of Open Access Journals (Sweden)

      Vojko Kilar

      2009-01-01

      Full Text Available Skoraj tretjina stanovanjskih enot v Sloveniji se nahaja v večstanovanjskih objektih. Večina tovrstnih zgradb je bila zgrajena po drugi svetovni vojni, ko je bila potreba po ustreznih nastavitvenih objektih največja. Narejeni so bili v okviru gradbenih možnosti in zahtev časa. Vsako leto v teh objektih izbruhne več kot 200 požarov s smrtnimi žrtvami in z veliko gmotno škodo. Zaradi velikih naporov v preteklih stoletjih, ki so bili usmerjeni predvsem v zamenjavo gorljivega gradbenega materiala z negorljivim in z razvojem gasilske službe, sta se število požarov in njihov obseg zmanjšala, vendar ne odpravila. Nov, večji napredek na področju požarne varnosti večstanovanjskih zgradb je tako očiten šele v zadnjih nekaj letih, ko veljajo tudi strožji predpisi za gradnjo tovrstnih objektov. Razvoj znanosti in stroke je tudi na tem področju prinesel več novih rešitev za izboljšanje stanja, kar potrjujejo izkušnje iz tujine. Žal je pri nas uveljavitev varnostnih principov še vedno odvisna predvsem od zavesti uporabnikov, finančnih sredstev, hkrati pa so določeni postopki izvedbe bistveno bolj zapleteni zaradi novih lastniških razmerij. S pomočjo statističnih rezultatov popisa 2002 in sodobnih zahtev varstva pred požarom se želi v članku prikazati današnje stanje tega problema na državni in občinski ravni ter nakazati možnosti izboljšanje stanja. Avtorja v članku ugotavljata, da sodobnim zahtevam ne ustreza pravzaprav nobena starejša večstanovanjska zgradba. K sreči izboljšuje stanje na tem področju dejstvo, da je večina objektov pri nas zgrajena iz negorljivih materialov (beton, opeka, ki omejujejo širjenje požara.

    15. Building Students' Understanding of Quadratic Equation Concept Using Naïve Geometry

      Science.gov (United States)

      Fachrudin, Achmad Dhany; Putri, Ratu Ilma Indra; Darmawijoyo

      2014-01-01

      The purpose of this research is to know how Naïve Geometry method can support students' understanding about the concept of solving quadratic equations. In this article we will discuss one activities of the four activities we developed. This activity focused on how students linking the Naïve Geometry method with the solving of the quadratic…

    16. Bazı Pestisitlerin Tetranychus urticae Koch'nin Ergin Yaşam Süresi ve Yumurta Verimine Etkileri

      Directory of Open Access Journals (Sweden)

      Mustafa Hakan BALCI

      2018-03-01

      Full Text Available Bu çalışmada deltamethrin, cypermethrin, imidacloprid ve thiacloprid etkili maddeye sahip insektisitlerin tarla uygulama dozu (T ve tarla uygulama dozunun yarısı (T/2'nın uygulandığı Tetranychus urticae (Acari: Tetranychidae erginlerinde üreme parametreleri ve yaşam süreleri incelenmiştir. İnsektisit dozları ve kontrol grubunda kullanılan saf su ilaçlama kulesi ile Petri kabındaki yaprak diskler üzerinde bulunan T. urticae'nin ergin bireylerine uygulanmıştır. Deltamethrin'in T/2 dozu uygulaması sonucunda, ergin bireylerinde ortalama yaşam süresi (5.35 gün ve ortalama ovipozisyon süresi (4.29 g kontrol grubuna (6.57 ve 5.44 g göre kısalmış, ayrıca yumurta sayısı/dişi oranıda azalmıştır. İmidacloprid, thiacloprid ve cypermethrin uygulanan her iki dozunda da T. urticae erginlerinde ortalama yaşam süresi ve ortalama preovipozisyon süresi kontrol grubu ile istatistiki olarak benzer bulunmuş ve dozlar arasında fark belirlenememiştir. İmidacloprid'in T/2 dozu uygulanan ergin bireylerin yumurta sayısı/dişi (64.03 oranının kontrol grubuna (39.96 göre arttığı belirlenmiştir. Sonuç olarak, imidacloprid ve deltamethrin’in T/2 dozlarının T. urticae ergin bireylerinde ortalama yaşam süresi, ortalama ovipozisyon süresi gibi bazı biyolojik özelikler üzerinde etkili olabileceği kanısına varılmıştır. 

    17. Université de Genève

      CERN Multimedia

      2008-01-01

      Ecole de physique - Département de physique nucléaire et corspusculaire 24, quai Ernest-Ansermet 1211 GENÈVE 4 Tél: (022) 379 62 73 - Fax: (022) 379 69 92 Lundi 1er décembre 2008 PARTICLE PHYSICS SEMINAR at 17.00 hrs – Stückelberg Auditorium Superconducting Interfaces between Insulating Oxide Prof. Jean-Marc TRISCONE / Université de Genève At interfaces between complex oxides, electronic systems with unusual properties can be generated. A striking example is the interface between LaAlO3 and SrTiO3, two good insulating perovskite oxides, which was found in 2004 to be conducting with a high mobility. We recently discovered that the ground state of this system is a superconducting condensate, with a critical temperature of about 200 mK. The characteristics observed for the superconducting transitions are consistent with a two-dimensional superconducting sheet as thin as a few nanometers. Recent field effect experiments revealed the sensitivity of the normal and superconducting states to the carrier d...

    18. Université de Genève

      CERN Multimedia

      2008-01-01

      Ecole de physique - Département de physique nucléaire et corspusculaire 24, quai Ernest-Ansermet - 1211 GENÈVE 4 Tél: (022) 379 62 73 - Fax: (022) 379 69 92 Lundi 1er décembre 2008 PARTICLE PHYSICS SEMINAR at 17.00 hrs – Stückelberg Auditorium Superconducting Interfaces between Insulating Oxide Prof. Jean-Marc TRISCONE / Université de Genève At interfaces between complex oxides, electronic systems with unusual properties can be generated. A striking example is the interface between LaAlO3 and SrTiO3, two good insulating perovskite oxides, which was found in 2004 to be conducting with a high mobility. We recently discovered that the ground state of this system is a superconducting condensate, with a critical temperature of about 200 mK. The characteristics observed for the superconducting transitions are consistent with a two-dimensional superconducting sheet as thin as a few nanometers. Recent field effect experiments revealed the sensitivity of the normal and superconducting states to the carrier ...

    19. Plasminogen Activator Inhibitor-1 Controls Vascular Integrity by Regulating VE-Cadherin Trafficking.

      Directory of Open Access Journals (Sweden)

      Anna E Daniel

      Full Text Available Plasminogen activator inhibitor-1 (PAI-1, a serine protease inhibitor, is expressed and secreted by endothelial cells. Patients with PAI-1 deficiency show a mild to moderate bleeding diathesis, which has been exclusively ascribed to the function of PAI-1 in down-regulating fibrinolysis. We tested the hypothesis that PAI-1 function plays a direct role in controlling vascular integrity and permeability by keeping endothelial cell-cell junctions intact.We utilized PAI-039, a specific small molecule inhibitor of PAI-1, to investigate the role of PAI-1 in protecting endothelial integrity. In vivo inhibition of PAI-1 resulted in vascular leakage from intersegmental vessels and in the hindbrain of zebrafish embryos. In addition PAI-1 inhibition in human umbilical vein endothelial cell (HUVEC monolayers leads to a marked decrease of transendothelial resistance and disrupted endothelial junctions. The total level of the endothelial junction regulator VE-cadherin was reduced, whereas surface VE-cadherin expression was unaltered. Moreover, PAI-1 inhibition reduced the shedding of VE-cadherin. Finally, we detected an accumulation of VE-cadherin at the Golgi apparatus.Our findings indicate that PAI-1 function is important for the maintenance of endothelial monolayer and vascular integrity by controlling VE-cadherin trafficking to and from the plasma membrane. Our data further suggest that therapies using PAI-1 antagonists like PAI-039 ought to be used with caution to avoid disruption of the vessel wall.

    20. TÜRKİYE’DE BASEL I, II ve III KURALLARINA UYUM SÜRECİ

      OpenAIRE

      Ezgi ASLAN KÜLAHİ; Göksel TİRYAKİ; Ahmet YILMAZ

      2013-01-01

      TÜRKİYE’DE BASEL I, I VE III KURALLARINA UYUM SÜRECİÖzet: Bu çalışma, Basel Kriterleri çerçevesinde Türk Bankacılık Sektörü’nde yapılan çalışmaları değerlendirerek sektörün Basel Kriterleri’ne uyum sürecinde hangi aşamada olduğunu incelemek amacıyla yapılmıştır. Çalışmada; Türkiye’de Basel I ve II Kriterleri’ne geçiş süreci: Basel I ve II’ye yönelik yapılan hazırlık çalışmaları , Basel Kriterleri’ne uyum kapsamında Türk Bankacılık Mevzuatı’nda yapılan yasal düzenlemeler ve BDDK tarafından ger...

    1. Aristoteles Ve İbn Sînâ’nın Reenkarnasyonu Reddi

      Directory of Open Access Journals (Sweden)

      Hasan Özalp

      2013-06-01

      Full Text Available Bu makalede düşünce tarihinin iki önemli düşünürü Aristoteles ve İbn Sînâ’nın reenkarnasyon/tenasüh hakkındaki görüşlerini inceledik. Her iki düşünürde reenkar-nasyonu reddetmektedir. Konuyu ele almadan önce kaynak olmaları bakımından Aristoteles ve İbn Sînâ’dan önceki bazı filozofların ruh ve reenkarnasyon hakkındaki görüşlerini araştırdık. Daha sonra da her iki filozofun ruh tanımlarım belirledikten sonra reenkarnasyone niçin reddettiklerini ortaya koymaya çalıştık. Nihayetinde görüşlerinde ki benzer ve farklı noktaları tespit için bir karşılaştırma yaptık

    2. Zeka, Öğrenme ve Düşünme

      Directory of Open Access Journals (Sweden)

      Emel Topçu

      2015-11-01

      Full Text Available Sokrates'ten bu yana huzurlu bir toplum için insanların eğitilmeleri ve liyakatlarına göre sınıflandırılmaları gerektiğine dair bir düşünce çeşitli versiyonları ile günümüze kadar gelmiştir. Daha sonraları en üst kategoride yer alan sınıfın üstünlüğünü ispat için çeşitli adlarla bilimsel çalışmalar denenmiştir. Modern çağın genellemeci alışkanlığı zekayı ve öğrenme yollarını da tek tipe indirgemektedir. ancak on dönemlerde inan zekaı ile ilgili çalışmalarla çoklu zeka anlayışı ortaya çıkmış, bu anlayışla birlikte öğrenme yolları da çeşitlenmiştir. Makalede çoklu zeka ve öğrenme yolları arasındaki ilişki incelenmektedir.

    3. Çeşitli kalsiyum boratların sentezi, karakterizasyonu ve alev geciktirici etkinliklerinin incelenmesi

      OpenAIRE

      DURĞUN, Zeynep Gülşah

      2010-01-01


        Türkiye sahip olduğu bor rezervleri ve cevherlerinin kalitesi ile dünyanın önde gelen ülkelerinden biri olmasına rağmen minerallerin çeşitliliği ve işlenebilirliği yetersizdir. Bu nedenle değişik endüstriyel uygulamalara yönelik sentetik bor bileşiklerinin elde edilmesi önemli bir ihtiyaçtır. Bilinen yaklaşık 230 çeşit bor bileşiği mevcuttur ve bir kalsiyum hekzaborat türevi olan Nobleit de bunlardan bir tanesidir. Yangınlarda can ve mal kaybın...

    4. Cortisol awakening response in drug-naïve panic disorder

      Directory of Open Access Journals (Sweden)

      Jakuszkowiak-Wojten K

      2016-06-01

      Full Text Available Katarzyna Jakuszkowiak-Wojten, Jerzy Landowski, Mariusz S Wiglusz, Wiesław Jerzy Cubała Department of Psychiatry, Medical University of Gdansk, Gdansk, Poland Background: It is unclear whether hypothalamic–pituitary–adrenal axis is involved in the pathophysiology of panic disorder (PD. The findings remain inconsistent. Cortisol awakening response (CAR is a noninvasive biomarker of stress system activity. We designed the study to assess CAR in drug-naïve PD patients.   Materials and methods: We assessed CAR in 14 psychotropic drug-naïve outpatients with PD and 14 healthy controls. The severity of PD was assessed with Panic and Agoraphobia Scale. The severity of anxiety and depression was screened with Hospital Anxiety and Depression Scale.   Results: No significant difference in CAR between PD patients and control group was found. No correlations were observed between CAR and anxiety severity measures in PD patients and controls.   Limitations: The number of participating subjects was relatively small, and the study results apply to nonsuicidal drug-naïve PD patients without agoraphobia and with short-illness duration. There was a lack of control on subjects’ compliance with the sampling instructions.  Conclusion: The study provides no support for elevated CAR levels in drug-naïve PD patients without agoraphobia. Keywords: panic disorder, PD, CAR, cortisol awakening response, HPA axis, hypothalamic–pituitary–adrenal axis

    5. Thermodynamic characterization of liquid metals at high temperature by isobaric expansion measurements

      International Nuclear Information System (INIS)

      Gathers, G.R.; Shaner, J.W.; Hodgson, W.M.

      1978-01-01

      Results of isobaric expansion measurements for platinum are presented, including simultaneous values for enthalpy, specific volume, temperature and electrical resistivity in tabular form as well as numerical fits up to 7500 K. The specific heat for the liquid is C/sub p/ = 5.85 +- 0.30 R and is essentially constant up to 7500 K. The bulk thermal expansion coefficient increases from approx. 7.5 x 10 -5 K -1 at melt to approx. 1.03 x 10 -4 K -1 at 7500 K. The heat of fusion observed is Δh = 0.14 +- 0.03 MJ/kg and the melting point slope with pressure is estimated to be dT/sub m//dp =31 +- 10 K/GPa. The estimated critical parameters are T/sub c/ = 9285 K, P/sub c/ = 0.9492 GPa, v/sub c/ = 2.120 x 10 -4 m 3 /kg, and z/sub c/ = 0.5085. Preliminary results of a new sound velocity technique are discussed for lead. This technique will allow determination of specific heat c/sub v/, isothermal compressibility K/sub T/ and the constant temperature volume derivatives of entropy and internal energy, as well as the Gruneisen parameter γ/sub G/

    6. HEYBELİADA RUHBAN OKULU (HRO MESELESİ: SİYASA, MENFAAT, PARANOYA VE ETKİLER

      Directory of Open Access Journals (Sweden)

      Mete Kaan KAYAPINAR

      2017-11-01

      Full Text Available 1844 yılında Heybeliada’daki Umut Tepesi’nde açılan Heybeliada Ruhban Okulu, İstanbul’un fethi sonrası Türklerin hâkimiyetine girmesine rağmen, Osmanlı İmparatorluğu tarafından varlığı tutulan İstanbul Rum Ortodoks Patrikhanesi’nin doğrudan ilgi ve yetki alanında hareket eden bir kurumdur. Doğu Bloku’nun çöküşü ve küreselleşme süreçleriyle birlikte dinî değerlerin toplumlar nezdinde yükselişe geçmesi, dinin dünya siyasetinde öneminin artıp daha belirgin bir araç olarak kullanılması, Türkiye’de hem İstanbul Rum Ortodoks Patrikhanesi’ni hem de 1971’de kapatılmış olan HRO’yu gündeme taşımıştır. 1971 yılından bu yana kapalı olan Heybeliada Ruhban Okulu, özellikle bu tarihten sonra Türkiye, Yunanistan ve Patrikhane arasında siyasî, hukukî ve kültürel gelişme ve ihtilaflara konu olan temel kurumsal bir sorun konumu kazanmıştır. Hatta bu sorun, son yıllarda ABD ve AB’nin de müdahil olduğu uluslararası bir nitelik kazanmıştır. Bu çalışmanın amacı, her şeyden önce bir hukuk devleti olarak Türkiye Cumhuriyeti’nin Heybeliada Ruhban Okulu’nun geleceği konusunda uygulayabileceği siyasayı, söz konusu okulun geçmişten günümüze İstanbul Rum Ortodoks Patrikhanesi ile ilişkileri, statüleri ve Türk-Yunan sorunlarına etkileri açısından salt hukukî mülahazalar çerçevesinde irdeleyerek ortaya koymaktır.

    7. Critical linear thermal expansion in the smectic-A phase near the nematic-smectic phase transition.

      Science.gov (United States)

      Anesta, E; Iannacchione, G S; Garland, C W

      2004-10-01

      Recent high-resolution x-ray investigations of the smectic- A (SmA) phase near the nematic-to-SmA transition provide information about the critical behavior of the linear thermal expansion coefficient alpha// parallel to the director. Combining such data with available volume thermal expansion alpha(V) data yields the in-plane linear expansion coefficient alpha(perpendicular) . The critical behaviors of alpha// and alpha(perpendicular) are the same as those for alpha(V) and the heat capacity Cp. However, for any given liquid crystal, alpha//(crit) and alpha(perpendicular)(crit) differ in sign. Furthermore, the quantity alpha// (crit) is positive for SmAd partial bilayer smectics, while it is negative for nonpolar SmAm monomeric smectics. This feature is discussed in terms of the molecular structural aspects of these smectic phases.

    8. Duchenne Müsküler Distrofi ve Gilbert"s Sendromu Birlikteliği: Bir Olgu Sunumu

      OpenAIRE

      İncecik, Faruk; Hergüner, Özlem M.; Mert, Gülen; Horoz, Özden; Altunbaşak, Şakir

      2014-01-01

      Gilbert"s sendromu konjuge olmayan hiperbilirubinemi ile karekterize bir hastalıktır. 5 yaşında erkek çocuğu hafif sarılık ile hastanemize getirildi. Hastanın karaciğer enzimleri ve kreatin fosfokinaz yüksekliği ile beraber ısrarcı unkonjuge hiperbilirubinemisi vardı. Normal hemoglobin ve retikülosit değerleri ile hemoliz dışlandı ve Gilbert"s sendromu tanısı konuldu. Kreatin kinaz değeri 15600 U/l idi ve distrofin geninde delesyon mevcuttu. Sonuç olarak hastaya Gilbert"s sendr...

    9. Negative thermal expansion materials

      International Nuclear Information System (INIS)

      Evans, J.S.O.

      1997-01-01

      The recent discovery of negative thermal expansion over an unprecedented temperature range in ZrW 2 O 8 (which contracts continuously on warming from below 2 K to above 1000 K) has stimulated considerable interest in this unusual phenomenon. Negative and low thermal expansion materials have a number of important potential uses in ceramic, optical and electronic applications. We have now found negative thermal expansion in a large new family of materials with the general formula A 2 (MO 4 ) 3 . Chemical substitution dramatically influences the thermal expansion properties of these materials allowing the production of ceramics with negative, positive or zero coefficients of thermal expansion, with the potential to control other important materials properties such as refractive index and dielectric constant. The mechanism of negative thermal expansion and the phase transitions exhibited by this important new class of low-expansion materials will be discussed. (orig.)

    10. Transgenerational soil-mediated differences between plants experienced or naïve to a grass invasion.

      Science.gov (United States)

      Deck, Anna; Muir, Adrianna; Strauss, Sharon

      2013-10-01

      Invasive species may undergo rapid change as they invade. Native species persisting in invaded areas may also experience rapid change over this short timescale relative to native populations in uninvaded areas. We investigated the response of the native Achillea millefolium to soil from Holcus lanatus-invaded and uninvaded areas, and we sought to determine whether differential responses between A. millefolium from invaded (invader experienced) and uninvaded (invader naïve) areas were mediated by soil community changes. Plants grown from seed from experienced and naïve areas responded differently to invaded and uninvaded soil with respect to germination time, biomass, and height. Overall, experienced plants grew faster and taller than their naïve counterparts. Naïve native plants showed negative feedbacks with their home soil and positive feedbacks with invaded soil; experienced plants were less responsive to soil differences. Our results suggest that native plants naïve to invasion may be more sensitive to soil communities than experienced plants, consistent with recent studies. While differences between naïve and experienced plants are transgenerational, our design cannot differentiate between differences that are genetically based, plastic, or both. Regardless, our results highlight the importance of seed source and population history in restoration, emphasizing the restoration potential of experienced seed sources.

    11. Lung Volume Reduction After Stereotactic Ablative Radiation Therapy of Lung Tumors: Potential Application to Emphysema

      Energy Technology Data Exchange (ETDEWEB)

      Binkley, Michael S. [Department of Radiation Oncology, Stanford University School of Medicine, Stanford, California (United States); Shrager, Joseph B. [Division of Thoracic Surgery, Department of Cardiothoracic Surgery, Stanford University School of Medicine, Stanford, California (United States); Stanford Cancer Institute, Stanford University School of Medicine, Stanford, California (United States); Leung, Ann N. [Department of Radiology, Stanford University School of Medicine, Stanford, California (United States); Popat, Rita [Department of Health Research and Policy, Stanford University School of Medicine, Stanford, California (United States); Trakul, Nicholas [Department of Radiation Oncology, Stanford University School of Medicine, Stanford, California (United States); Department of Radiation Oncology, University of Southern California Keck School of Medicine, Los Angeles, California (United States); Atwood, Todd F.; Chaudhuri, Aadel [Department of Radiation Oncology, Stanford University School of Medicine, Stanford, California (United States); Maxim, Peter G. [Department of Radiation Oncology, Stanford University School of Medicine, Stanford, California (United States); Stanford Cancer Institute, Stanford University School of Medicine, Stanford, California (United States); Diehn, Maximilian, E-mail: Diehn@Stanford.edu [Department of Radiation Oncology, Stanford University School of Medicine, Stanford, California (United States); Stanford Cancer Institute, Stanford University School of Medicine, Stanford, California (United States); Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, California (United States); Loo, Billy W., E-mail: BWLoo@Stanford.edu [Department of Radiation Oncology, Stanford University School of Medicine, Stanford, California (United States); Stanford Cancer Institute, Stanford University School of Medicine, Stanford, California (United States)

      2014-09-01

      Purpose: Lung volume reduction surgery (LVRS) improves dyspnea and other outcomes in selected patients with severe emphysema, but many have excessive surgical risk for LVRS. We analyzed the dose-volume relationship for lobar volume reduction after stereotactic ablative radiation therapy (SABR) of lung tumors, hypothesizing that SABR could achieve therapeutic volume reduction if applied in emphysema. Methods and Materials: We retrospectively identified patients treated from 2007 to 2011 who had SABR for 1 lung tumor, pre-SABR pulmonary function testing, and ≥6 months computed tomographic (CT) imaging follow-up. We contoured the treated lobe and untreated adjacent lobe(s) on CT before and after SABR and calculated their volume changes relative to the contoured total (bilateral) lung volume (TLV). We correlated lobar volume reduction with the volume receiving high biologically effective doses (BED, α/β = 3). Results: 27 patients met the inclusion criteria, with a median CT follow-up time of 14 months. There was no grade ≥3 toxicity. The median volume reduction of the treated lobe was 4.4% of TLV (range, −0.4%-10.8%); the median expansion of the untreated adjacent lobe was 2.6% of TLV (range, −3.9%-11.6%). The volume reduction of the treated lobe was positively correlated with the volume receiving BED ≥60 Gy (r{sup 2}=0.45, P=.0001). This persisted in subgroups determined by high versus low pre-SABR forced expiratory volume in 1 second, treated lobe CT emphysema score, number of fractions, follow-up CT time, central versus peripheral location, and upper versus lower lobe location, with no significant differences in effect size between subgroups. Volume expansion of the untreated adjacent lobe(s) was positively correlated with volume reduction of the treated lobe (r{sup 2}=0.47, P<.0001). Conclusions: We identified a dose-volume response for treated lobe volume reduction and adjacent lobe compensatory expansion after lung tumor SABR, consistent across

    12. Rapid estimate of solid volume in large tuff cores using a gas pycnometer

      Energy Technology Data Exchange (ETDEWEB)

      Thies, C. [ed.; Geddis, A.M.; Guzman, A.G. [and others

      1996-09-01

      A thermally insulated, rigid-volume gas pycnometer system has been developed. The pycnometer chambers have been machined from solid PVC cylinders. Two chambers confine dry high-purity helium at different pressures. A thick-walled design ensures minimal heat exchange with the surrounding environment and a constant volume system, while expansion takes place between the chambers. The internal energy of the gas is assumed constant over the expansion. The ideal gas law is used to estimate the volume of solid material sealed in one of the chambers. Temperature is monitored continuously and incorporated into the calculation of solid volume. Temperature variation between measurements is less than 0.1{degrees}C. The data are used to compute grain density for oven-dried Apache Leap tuff core samples. The measured volume of solid and the sample bulk volume are used to estimate porosity and bulk density. Intrinsic permeability was estimated from the porosity and measured pore surface area and is compared to in-situ measurements by the air permeability method. The gas pycnometer accommodates large core samples (0.25 m length x 0.11 m diameter) and can measure solid volume greater than 2.20 cm{sup 3} with less than 1% error.

    13. Computer simulation of preflight blood volume reduction as a countermeasure to fluid shifts in space flight

      Science.gov (United States)

      Simanonok, K. E.; Srinivasan, R.; Charles, J. B.

      1992-01-01

      Fluid shifts in weightlessness may cause a central volume expansion, activating reflexes to reduce the blood volume. Computer simulation was used to test the hypothesis that preadaptation of the blood volume prior to exposure to weightlessness could counteract the central volume expansion due to fluid shifts and thereby attenuate the circulatory and renal responses resulting in large losses of fluid from body water compartments. The Guyton Model of Fluid, Electrolyte, and Circulatory Regulation was modified to simulate the six degree head down tilt that is frequently use as an experimental analog of weightlessness in bedrest studies. Simulation results show that preadaptation of the blood volume by a procedure resembling a blood donation immediately before head down bedrest is beneficial in damping the physiologic responses to fluid shifts and reducing body fluid losses. After ten hours of head down tilt, blood volume after preadaptation is higher than control for 20 to 30 days of bedrest. Preadaptation also produces potentially beneficial higher extracellular volume and total body water for 20 to 30 days of bedrest.

    14. Negative thermal expansion materials: technological key for control of thermal expansion.

      Science.gov (United States)

      Takenaka, Koshi

      2012-02-01

      Most materials expand upon heating. However, although rare, some materials contract upon heating. Such negative thermal expansion (NTE) materials have enormous industrial merit because they can control the thermal expansion of materials. Recent progress in materials research enables us to obtain materials exhibiting negative coefficients of linear thermal expansion over -30 ppm K -1 . Such giant NTE is opening a new phase of control of thermal expansion in composites. Specifically examining practical aspects, this review briefly summarizes materials and mechanisms of NTE as well as composites containing NTE materials, based mainly on activities of the last decade.

    15. Negative thermal expansion materials: technological key for control of thermal expansion

      Directory of Open Access Journals (Sweden)

      Koshi Takenaka

      2012-01-01

      Full Text Available Most materials expand upon heating. However, although rare, some materials contract upon heating. Such negative thermal expansion (NTE materials have enormous industrial merit because they can control the thermal expansion of materials. Recent progress in materials research enables us to obtain materials exhibiting negative coefficients of linear thermal expansion over −30 ppm K−1. Such giant NTE is opening a new phase of control of thermal expansion in composites. Specifically examining practical aspects, this review briefly summarizes materials and mechanisms of NTE as well as composites containing NTE materials, based mainly on activities of the last decade.

    16. Negative thermal expansion materials: technological key for control of thermal expansion

      International Nuclear Information System (INIS)

      Takenaka, Koshi

      2012-01-01

      Most materials expand upon heating. However, although rare, some materials contract upon heating. Such negative thermal expansion (NTE) materials have enormous industrial merit because they can control the thermal expansion of materials. Recent progress in materials research enables us to obtain materials exhibiting negative coefficients of linear thermal expansion over −30 ppm K −1 . Such giant NTE is opening a new phase of control of thermal expansion in composites. Specifically examining practical aspects, this review briefly summarizes materials and mechanisms of NTE as well as composites containing NTE materials, based mainly on activities of the last decade. (topical review)

    17. Gluten Unu İlavesinin Hamurun Reolojik Özellikleri ve Ekmeğin Kalitesine Etkisi

      Directory of Open Access Journals (Sweden)

      Hazım Özkaya

      2015-02-01

      Full Text Available Farklı özellikteki iki un örneğinden laboratuvarda elde edilen değişik özellikteki gluten unları ile bir nişasta fabrikası yan ürünü olan ticari gluten unu 74 ve 80 randımanlı unlara %1, %3, %5, %7 ve %10 oranlarında katılarak hamurun reolojik özellikleri ve ekmeğin kalitesine etkileri araştırılmıştır. Gluten unu katılan örneklerin farinograftaki su absorbsiyonları yükselmiştir. Gelişme süresi 50 oC de kurutulan gluten unlarından olumlu yönde etkilenmiştir. Stabilite değeri, yoğurma tolerans sayısı, yumuşama derecesi ve valorimetre değeri laboratuvarda elde edilen gluten unlarından olumlu, ticari gluten unundan ise olumsuz yönde etkilenmiştir. Ekstensografta hamurun uzama mukavemeti una gluten unu katıldığı zaman artmıştır. Hamurun uzama kabiliyeti 70 oC de kurutulan gluten unu katılmış örneklerde azalmıştır. Enerji değeri ise 70 oC de kurutulan gluten unu ve %10 ticari gluten unu katkılı örnekler dışında olumlu yönde etkilenmiştir. Ekmek hacmi ve değer sayısı, 50 oC de kurutulan gluten unundan olumlu, 70 oC de kurutulandan ise olumsuz yönde etkilenmiştir. Ticari gluten unu 80 randımanlı unların ekmek hacmi ve değer sayısını arttırmıştır.

    18. Stem cells. m6A mRNA methylation facilitates resolution of naïve pluripotency toward differentiation.

      Science.gov (United States)

      Geula, Shay; Moshitch-Moshkovitz, Sharon; Dominissini, Dan; Mansour, Abed AlFatah; Kol, Nitzan; Salmon-Divon, Mali; Hershkovitz, Vera; Peer, Eyal; Mor, Nofar; Manor, Yair S; Ben-Haim, Moshe Shay; Eyal, Eran; Yunger, Sharon; Pinto, Yishay; Jaitin, Diego Adhemar; Viukov, Sergey; Rais, Yoach; Krupalnik, Vladislav; Chomsky, Elad; Zerbib, Mirie; Maza, Itay; Rechavi, Yoav; Massarwa, Rada; Hanna, Suhair; Amit, Ido; Levanon, Erez Y; Amariglio, Ninette; Stern-Ginossar, Noam; Novershtern, Noa; Rechavi, Gideon; Hanna, Jacob H

      2015-02-27

      Naïve and primed pluripotent states retain distinct molecular properties, yet limited knowledge exists on how their state transitions are regulated. Here, we identify Mettl3, an N(6)-methyladenosine (m(6)A) transferase, as a regulator for terminating murine naïve pluripotency. Mettl3 knockout preimplantation epiblasts and naïve embryonic stem cells are depleted for m(6)A in mRNAs, yet are viable. However, they fail to adequately terminate their naïve state and, subsequently, undergo aberrant and restricted lineage priming at the postimplantation stage, which leads to early embryonic lethality. m(6)A predominantly and directly reduces mRNA stability, including that of key naïve pluripotency-promoting transcripts. This study highlights a critical role for an mRNA epigenetic modification in vivo and identifies regulatory modules that functionally influence naïve and primed pluripotency in an opposing manner. Copyright © 2015, American Association for the Advancement of Science.

    19. Atasözü ve Deyim Çevirilerinin Mona Baker Çeviri Stratejilerine Göre İncelenmesi

      Directory of Open Access Journals (Sweden)

      Perihan YALÇIN

      2017-12-01

      Full Text Available Bu makalede, atasözü ve deyim çevirilerinde kullanılan stratejiler Mona Baker’in çeviri stratejilerine dayanılarak incelenmiştir. Bu stratejilerden bir kısmı, benzer anlam benzer biçimle çeviri (tam eşdeğerlik, benzer anlam farklı biçimle çeviri (kısmî eşdeğerlik, açımlama ve çıkarma yöntemiyle çeviridir. Çalışmanın amacı, deyim ve atasözleri çevirilerinde kullanılan çeviri stratejilerini belirlemek, sözü geçen çevirilerdeki eşdeğerlik ve farklılıkları göstermektir. Araştırma, yapılan çeviri incelemeleri sonucunda kültür faktörünün çevirideki yeri ve kaynak ve hedef dil arasındaki farklılıklara dikkat çekmek açısından önemlidir. Çalışmada, yazarlar tarafından seçilen atasözleri ve deyim çevirileri, benzer anlam benzer biçimle çeviri (tam eşdeğerlik, benzer anlam farklı biçimle çeviri (kısmî eşdeğerlik , açımlama ve çıkarma yöntemiyle çeviri olmak üzere dört yöntemden yola çıkılarak değerlendirilecektir. Yapılan bulgular neticesinde, atasözleri ve deyim çevirilerinde biçimsel ve anlamsal eşdeğerliğin sağlandığı durumlar olduğu gibi biçimsel ve anlamsal farklılıklar da dikkat çekmektedir. Bu farklılıklar farklı iki dilin sahip olduğu kültür çeşitliliğinden gelmektedir. Atasözü ve deyim çevirileri zor bir iştir. Bir dilden başka bir dile, o dile ait bir kültürü, öğüdü, dersi aynı ifadeleri kullanarak aynı sözdizimiyle aktarmak çok nadir bir durumdur. Bu sebeple, incelenen atasözü ve deyimlerde daha çok farklı ifadelere ve açıklamalara yer verilerek çeviriler yapılmıştır. Çevirilerde çoğunlukla ekleme ve çıkarma yöntemine başvurulmuş erek dilde en iyi anlam yakalanmaya çalışılmıştır. Kelime ya da cümlelerde yapılan çıkarmalar, eklemeler ya da süslemeler çevirmenin o dili nasıl kullanabildiğini ve o dilin zenginliğini göstermektedir; fakat zaman zaman kaynak dildeki ifadelere erek

    20. Kapak ve İçindekiler

      Directory of Open Access Journals (Sweden)

      Kapak İçindekiler

      2016-12-01

      Full Text Available Bu dergi, aşağıda listelenen veri tabanları tarafından taranmaktadır / This journal is indexed by the following abstracting and indexing databasesBASE, CAB Abstracts, CAS (Chemical Abstracts Service, CiteFactor, CNKI Scholar, DOAJ, DRJI, EBSCO Discovery Service (EDS, Google Scholar, Index Copernicus, InfoBase Index, JournalTOCs, OAJI, ResearchBib, Ulakbim TR Dizin (Mühendislik ve Temel Bilimler, WorldCat (OCLC, Zentralblatt MATH

    1. Kapak ve İçindekiler

      Directory of Open Access Journals (Sweden)

      Kapak ve İçindekiler

      2017-12-01

      Full Text Available Bu dergi, aşağıda listelenen veri tabanları tarafından taranmaktadır / This journal is indexed by the following abstracting and indexing databases:BASE, CAB Abstracts, CAS (Chemical Abstracts Service, CiteFactor, CNKI Scholar, DOAJ, DRJI, EBSCO Discovery Service (EDS, Google Scholar, Index Copernicus, InfoBase Index, JournalTOCs, OAJI, ResearchBib, Ulakbim TR Dizin (Mühendislik ve Temel Bilimler, WorldCat (OCLC, Zentralblatt MATH

    2. Kapak ve İçindekiler

      Directory of Open Access Journals (Sweden)

      Kapak ve İçindekiler

      2018-04-01

      Full Text Available Bu dergi, aşağıda listelenen veri tabanları tarafından taranmaktadır / This journal is indexed by the following abstracting and indexing databases:BASE, CAB Abstracts, CAS (Chemical Abstracts Service, CiteFactor, CNKI Scholar, DOAJ, DRJI, EBSCO Discovery Service (EDS, Google Scholar, Index Copernicus, InfoBase Index, JournalTOCs, OAJI, ResearchBib, Ulakbim TR Dizin (Mühendislik ve Temel Bilimler, WorldCat (OCLC, Zentralblatt MATH

    3. Kapak ve İçindekiler

      Directory of Open Access Journals (Sweden)

      Kapak ve İçindekiler

      2017-08-01

      Full Text Available Bu dergi, aşağıda listelenen veri tabanları tarafından taranmaktadır / This journal is indexed by the following abstracting and indexing databases:BASE, CAB Abstracts, CAS (Chemical Abstracts Service, CiteFactor, CNKI Scholar, DOAJ, DRJI, EBSCO Discovery Service (EDS, Google Scholar, Index Copernicus, InfoBase Index, JournalTOCs, OAJI, ResearchBib, Ulakbim TR Dizin (Mühendislik ve Temel Bilimler, WorldCat (OCLC, Zentralblatt MATH

    4. Kapak ve İçindekiler

      Directory of Open Access Journals (Sweden)

      Kapak ve İçindekiler

      2017-04-01

      Full Text Available Bu dergi, aşağıda listelenen veri tabanları tarafından taranmaktadır / This journal is indexed by the following abstracting and indexing databases:BASE, CAB Abstracts, CAS (Chemical Abstracts Service, CiteFactor, CNKI Scholar, DOAJ, DRJI, EBSCO Discovery Service (EDS, Google Scholar, Index Copernicus, InfoBase Index, JournalTOCs, OAJI, ResearchBib, Ulakbim TR Dizin (Mühendislik ve Temel Bilimler, WorldCat (OCLC, Zentralblatt MATH

    5. KÜRESELLEŞMEDEN GELENEKSELE DÖNÜŞTE SLOW FOOD VE CİTTASLOW HAREKETİ

      OpenAIRE

      SAĞIR, GÜLHAN

      2017-01-01

      Küreselleşme, günümüzde kentlerideğişime uğratmakta ve yerel düzeyde yaşamı giderek daha fazla etkilemektedir.Kentler tek tipleşmeye doğru giderken bireylerin yaşam tarzları da birbirinebenzemekte ve farklılıklar ortadan kalkmaktadır. Küresel sistemde mekâna özgüfarklılıklar ve özellikler daha az belirgindir; yaşam daha hızlıdır. Budeğişimle gelen hızlı yeme ve içme alışkanlığı insan sağlığına zarar verirken, mekânlarise kimliksizleşmektedir. Küreselleşmenin insan yaşamı üzerindeki olumsuzetk...

    6. Use of pressure manifestations following the water plasma expansion for phytomass disintegration.

      Science.gov (United States)

      Maroušek, Josef; Kwan, Jason Tai Hong

      2013-01-01

      A prototype capable of generating underwater high-voltage discharges (3.5 kV) coupled with water plasma expansion was constructed. The level of phytomass disintegration caused by transmission of the pressure shockwaves (50-60 MPa) followed by this expansion was analyzed using gas adsorption techniques. The dynamics of the external surface area and the micropore volume on multiple pretreatment stages of maize silage and sunflower seeds was approximated with robust analytical techniques. The multiple increases on the reaction surface were manifest in up to a 15% increase in cumulative methane production, which was itself manifest in the overall acceleration of the anaerobic fermentation process. Disintegration of the sunflower seeds allowed up to 45% higher oil yields using the same operating pressure.

    7. Kahramanmaraş Koşullarında Farklı Ekim Zamanlarının Isatis tinctoria ve Isatis buschiana Türlerinin Verim ve Bazı Agronomik Özellikleri Üzerine Etkileri

      OpenAIRE

      Çömlekcioğlu, N.; Efe, L.; Karaman, Ş.

      2014-01-01

      Bu çalışma, 2007-2008 ve 2008-2009 yetiştirme sezonunda Kahramanmaraş ekolojik koşullarında, farklı ekim zamanlarının (Ekim, Kasım, Şubat ve Mart) iki Isatis Isatis tinctoria ve Isatis buschiana türünün verim ve kalitesi üzerine etkisini belirlemek amacıyla tesadüf parselleri deneme desenine göre üç tekerrürlü olarak yürütülmüştür. Çalışmada Isatis türlerinin Kahramanmaraş iklim şartlarına en uygun ekim zamanının belirlenmesi amaçlanmıştır. İki yıllık sonuçlara göre, neredeyse incelenen bütün...

    8. Effect of water volume based on water absorption and mixing time on physical properties of tapioca starch – wheat composite bread

      Science.gov (United States)

      Prameswari, I. K.; Manuhara, G. J.; Amanto, B. S.; Atmaka, W.

      2018-05-01

      Tapioca starch application in bread processing change water absorption level by the dough, while sufficient mixing time makes the optimal water absorption. This research aims to determine the effect of variations in water volume and mixing time on physical properties of tapioca starch – wheat composite bread and the best method for the composite bread processing. This research used Complete Randomized Factorial Design (CRFD) with two factors: variations of water volume (111,8 ml, 117,4 ml, 123 ml) and mixing time (16 minutes, 17 minutes 36 seconds, 19 minutes 12 seconds). The result showed that water volume significantly affected on dough volume, bread volume and specific volume, baking expansion, and crust thickness. Mixing time significantly affected on dough volume and specific volume, bread volume and specific volume, baking expansion, bread height, and crust thickness. While the combination of water volume and mixing time significantly affected for all physical properties parameters except crust thickness.

    9. Geleneksel ve Elektronik Eser Sahiplerinin Telif Hakları, Dijital Haklar Yönetimi: Uluslararası Düzenlemeler ve Fikir ve Sanat Eserleri Kanunu Çerçevesinde Bir Değerlendirme = Copyright of Traditional and Electronic Works’ Owners, Digital Rights Management: An Evaluation within the Framework of International Regulations and Law on Intellectual and Artistic Works

      OpenAIRE

      Metin Turan

      2016-01-01

      Bilgi ve iletişim teknolojilerinin gelişmesi ile fikri haklar alanında da değişiklikler kaçınılmaz olmuştur. Teknolojik imkânların gelişimi ve dijitalleşme ile dijital eserlerin üretimiyle birlikte telif haklarında sorunlar ortaya çıkmaktadır. Çalışmada, genel olarak, telif haklarının dijital eserlere ve dijital haklar yönetimine yönelik incelenmesi amaçlanmaktadır. Çalışmanın kapsamını dijital haklar yönetimi çerçevesinde 5846 sayılı Fikir ve Sanat Eserleri Kanunu oluşturmaktadır. Bu kapsamd...

    10. Thermal expansion of coking coals

      Energy Technology Data Exchange (ETDEWEB)

      Orlik, M.; Klimek, J. (Vyzkumny a Zkusebni Ustav Nova Hut, Ostrava (Czechoslovakia))

      1992-12-01

      Analyzes expansion of coal mixtures in coke ovens during coking. Methods for measuring coal expansion on both a laboratory and pilot plant scale are comparatively evaluated. The method, developed, tested and patented in Poland by the Institute for Chemical Coal Processing in Zabrze (Polish standard PN-73/G-04522), is discussed. A laboratory device developed by the Institute for measuring coal expansion is characterized. Expansion of black coal from 10 underground mines in the Ostrava-Karvina coal district and from 9 coal mines in the Upper Silesia basin in Poland is comparatively evaluated. Investigations show that coal expansion reaches a maximum for coal types with a volatile matter ranging from 20 to 25%. With increasing volatile matter in coal, its expansion decreases. Coal expansion increases with increasing swelling index. Coal expansion corresponds with coal dilatation. With increasing coal density its expansion increases. Coal mixtures should be selected in such a way that their expansion does not cause a pressure exceeding 40 MPa. 11 refs.

    11. Negative and Zero Thermal Expansion NiTi Superelastic Shape Memory Alloy by Microstructure Engineering

      Science.gov (United States)

      Sun, Qingping; Yu, Chao; Kang, Guozheng

      2018-03-01

      We report recent progress in tailoring the thermal expansion (TE) of nanocrystalline (NC) NiTi by microstructure hierarchical design and control without composition change. Fabrication and characterization methods are outlined and preliminary results of both experiment and mechanism-based modeling are presented to understand and get insight into the unusual TE phenomena. The important roles of the intrinsic thermal expansion anisotropy of B19' lattice and the suppression of phase transition by the extrinsic fabricated microstructure (cold rolling and annealing, grain size, defects, textures and volume fractions of nanoscaled B2 and B19' lattices) in the overall macroscopic TE behaviors of the superelastic NC NiTi polycrystal SMAs are emphasized.

    12. Negative and Zero Thermal Expansion NiTi Superelastic Shape Memory Alloy by Microstructure Engineering

      Science.gov (United States)

      Sun, Qingping; Yu, Chao; Kang, Guozheng

      2018-02-01

      We report recent progress in tailoring the thermal expansion (TE) of nanocrystalline (NC) NiTi by microstructure hierarchical design and control without composition change. Fabrication and characterization methods are outlined and preliminary results of both experiment and mechanism-based modeling are presented to understand and get insight into the unusual TE phenomena. The important roles of the intrinsic thermal expansion anisotropy of B19' lattice and the suppression of phase transition by the extrinsic fabricated microstructure (cold rolling and annealing, grain size, defects, textures and volume fractions of nanoscaled B2 and B19' lattices) in the overall macroscopic TE behaviors of the superelastic NC NiTi polycrystal SMAs are emphasized.

    13. Virial Expansion Bounds

      Science.gov (United States)

      Tate, Stephen James

      2013-10-01

      In the 1960s, the technique of using cluster expansion bounds in order to achieve bounds on the virial expansion was developed by Lebowitz and Penrose (J. Math. Phys. 5:841, 1964) and Ruelle (Statistical Mechanics: Rigorous Results. Benjamin, Elmsford, 1969). This technique is generalised to more recent cluster expansion bounds by Poghosyan and Ueltschi (J. Math. Phys. 50:053509, 2009), which are related to the work of Procacci (J. Stat. Phys. 129:171, 2007) and the tree-graph identity, detailed by Brydges (Phénomènes Critiques, Systèmes Aléatoires, Théories de Jauge. Les Houches 1984, pp. 129-183, 1986). The bounds achieved by Lebowitz and Penrose can also be sharpened by doing the actual optimisation and achieving expressions in terms of the Lambert W-function. The different bound from the cluster expansion shows some improvements for bounds on the convergence of the virial expansion in the case of positive potentials, which are allowed to have a hard core.

    14. Gelişen Teknolojiyle Birlikte Değişen Pazarlama Yöntemleri ve Dijital Pazarlama

      OpenAIRE

      BULUNMAZ, Barış

      2016-01-01

      Teknolojinin değişim hızı ve yenilenme süreci, her geçen günçok daha hızlı bir şekilde ilerlemektedir. Teknolojinin devinim hızınınyükselmesi ve her yeniliğin bir değişimi beraberinde getirmesi neticesinde,sosyal yaşamın içinde ve kurumsal hayatın işleyişinde büyük farklılıklar meydanagelmiştir. İnsanların davranış şekilleri ve alışkanlıkları teknolojininyarattığı yeni düzene bağlı olarak farklı bir eksene doğru kayarken, ticarikurumların da müşterileriyle olan ilişkileri ve iletişimleri deği...

    15. 76 FR 24883 - DNB Exports LLC, and AFI Elektromekanikanik Ve Elektronik San. Tic. Ltd. Sti. v. Barsan Global...

      Science.gov (United States)

      2011-05-03

      ... FEDERAL MARITIME COMMISSION [Docket No. 11-07] DNB Exports LLC, and AFI Elektromekanikanik Ve Elektronik San. Tic. Ltd. Sti. v. Barsan Global Lojistiks Ve Gumruk Musavirligi A.S., Barsan International... AFI Elektromekanikanik Ve Elektronik San. Tic. Ltd. Sti. (``AFI''), hereinafter ``Complainants...

    16. Study of the multifragmentation in central collisions of the system: 129Xe + natSn between 32 and 50 MeV/A: measurement of collective expansion energy and of freeze-out volume

      International Nuclear Information System (INIS)

      Salou, S.

      1997-01-01

      The multifragmentation of the nuclear system formed in the central collisions of the Xe+Sn reaction between 32 and 50 MeV/A has been studied with the INDRA detector. A tensorial analyse is used to select central collisions. An important part of the charge (about 85 %) is isotropically emitted. The charge partitions have the characteristics of a simultaneous multiple fragment emission. The shape of the fragment kinetic energy distributions together with the reduced velocity correlation functions indicate that the fragmentation is a simultaneous process that occurs at low density. A comparison between the experimental data and predictions of the statistical multifragmentation model of Copenhagen (SMM) shows that charge partitions agree with the hypothesis of a thermodynamical equilibrium, whereas, kinetic observables are more constraining to the model and difficult to reproduce. However, fragments correlation functions are used in order to extract the freeze-out volume and the collective radial energy. At 50 MeV/A, the freeze-out volume is estimated to be 2.7 times the normal volume. It decreases with incident energy to be nearly twice the normal volume at 32 MeV/S. The collective energy evolves from 0 to 1.3 MeV/A with the bombarding energy. This expansion is not purely thermal and originates probably from a dynamical compression developed in the early stage of the collision. (author)

    17. Almanya'da sığır ve dana eti piyasa düzeni ve Türkiye için sığır eti pazarlamasında model oluşturabilme olanakları üzerine bir araştırma

      OpenAIRE

      KILIÇ, Sevinç

      2006-01-01

      Almanya'da Sığır ve Dana Eti Piyasa Düzeni ve Türkiye İçin Sığır Eti PazarlamasındaModel Oluşturabilme Olanakları Üzerine Bir AraştırmaBu araştırmada Avrupa Birliği Ortak Tarım Politikası kapsamında Sığır ve Dana Eti OrtakPiyasa Düzeni'nde uygulanmış ve uygulanmakta olan politikalar, Almanya'nın kasaplıkhayvan ve et piyasa yapısı ile ilgili düzenlemeleri, Almanya'da kasaplık hayvan ve etpazarlamasının tarihsel gelişimi detaylı olarak incelenmiştir.Türkiye'de 2001-2004 yıl...

    18. Ortaokul 5. ve 6. Sınıf Fen Bilimleri Öğretim Programının Kazanım ve İçerik İlişkisinin Değerlendirilmesi

      OpenAIRE

      Ocak, Gürbüz; Kutlu Kalender, M. Damla

      2018-01-01

      Bu çalışma Milli Eğitim Bakanlığı tarafından basılmış 5. ve 6. Sınıf Fen Bilimleri ders kitaplarındaki içeriğin, ortaokul 5. ve 6. Sınıf Fen Bilimleri dersi öğretim programındaki kazanımlara uygunluk düzeyini değerlendirmeyi amaçlamıştır. Öncelikle 2015-2016 eğitim öğretim yılı 5. ve 6.sınıf öğretim programındaki kazanımlarla 5.ve 6. sınıf fen bilimleri ders kitaplarındaki içerikler incelenmiştir. Değerlendirme için ölçme aracı olarak kazanım-içerik değerlendirme rubriği hazırlanmıştır. Geliş...

    19. Siber Saldırılar Siber Savaşlar ve Etkileri

      OpenAIRE

      Kara, Mahruze

      2013-01-01

      74 pages. İnternetin ortaya çıkması ile yararlarından faydalanılmaktadır. Ancak internetin zararları da mevcuttur. İnternet, dünya dengelerini değiştirmektedir. İnternet, siber saldırılara ve siber savaşlara aracılık eden bir alan olmuştur. Siber saldırılar, ülkelerin ulusal ve ekonomik güvenliğini sarsmaktadır. Siber savaşlar 5. boyutta yapılmaktadır. Bu çalışmada siber silahlar ile siber saldırılar ve siber savaşların etkileri işlenmiştir. Siber güvenlik önlemleri için çöz...

    20. Ultra-low thermal expansion realized in giant negative thermal expansion materials through self-compensation

      Science.gov (United States)

      Shen, Fei-Ran; Kuang, Hao; Hu, Feng-Xia; Wu, Hui; Huang, Qing-Zhen; Liang, Fei-Xiang; Qiao, Kai-Ming; Li, Jia; Wang, Jing; Liu, Yao; Zhang, Lei; He, Min; Zhang, Ying; Zuo, Wen-Liang; Sun, Ji-Rong; Shen, Bao-Gen

      2017-10-01

      Materials with zero thermal expansion (ZTE) or precisely tailored thermal expansion are in urgent demand of modern industries. However, the overwhelming majority of materials show positive thermal expansion. To develop ZTE or negative thermal expansion (NTE) materials as compensators has become an important challenge. Here, we present the evidence for the realization of ultra-low thermal expansion in Mn-Co-Ge-In particles. The bulk with the Ni2In-type hexagonal structure undergoes giant NTE owing to a martensitic magnetostructural transition. The major finding is that the thermal expansion behavior can be totally controlled by modulating the crystallinity degree and phase transition from atomic scale. Self-compensation effect leads to ultra-low thermal expansion with a linear expansion coefficient as small as +0.68 × 10-6/K over a wide temperature range around room temperature. The present study opens an avenue to reach ZTE particularly from the large class of giant NTE materials based on phase transition.

    1. Ultra-low thermal expansion realized in giant negative thermal expansion materials through self-compensation

      Directory of Open Access Journals (Sweden)

      Fei-Ran Shen

      2017-10-01

      Full Text Available Materials with zero thermal expansion (ZTE or precisely tailored thermal expansion are in urgent demand of modern industries. However, the overwhelming majority of materials show positive thermal expansion. To develop ZTE or negative thermal expansion (NTE materials as compensators has become an important challenge. Here, we present the evidence for the realization of ultra-low thermal expansion in Mn–Co–Ge–In particles. The bulk with the Ni2In-type hexagonal structure undergoes giant NTE owing to a martensitic magnetostructural transition. The major finding is that the thermal expansion behavior can be totally controlled by modulating the crystallinity degree and phase transition from atomic scale. Self-compensation effect leads to ultra-low thermal expansion with a linear expansion coefficient as small as +0.68 × 10−6/K over a wide temperature range around room temperature. The present study opens an avenue to reach ZTE particularly from the large class of giant NTE materials based on phase transition.

    2. Early Medicaid Expansion In Connecticut Stemmed The Growth In Hospital Uncompensated Care.

      Science.gov (United States)

      Nikpay, Sayeh; Buchmueller, Thomas; Levy, Helen

      2015-07-01

      As states continue to debate whether or not to expand Medicaid under the Affordable Care Act (ACA), a key consideration is the impact of expansion on the financial position of hospitals, including their burden of uncompensated care. Conclusive evidence from coverage expansions that occurred in 2014 is several years away. In the meantime, we analyzed the experience of hospitals in Connecticut, which expanded Medicaid coverage to a large number of childless adults in April 2010 under the ACA. Using hospital-level panel data from Medicare cost reports, we performed difference-in-differences analyses to compare the change in Medicaid volume and uncompensated care in the period 2007-13 in Connecticut to changes in other Northeastern states. We found that early Medicaid expansion in Connecticut was associated with an increase in Medicaid discharges of 7-9 percentage points, relative to a baseline rate of 11 percent, and an increase of 7-8 percentage points in Medicaid revenue as a share of total revenue, relative to a baseline share of 10 percent. Also, in contrast to the national and regional trends of increasing uncompensated care during this period, hospitals in Connecticut experienced no increase in uncompensated care. We conclude that uncompensated care in Connecticut was roughly one-third lower than what it would have been without early Medicaid expansion. The results suggest that ACA Medicaid expansions could reduce hospitals' uncompensated care burden. Project HOPE—The People-to-People Health Foundation, Inc.

    3. Human brain expansion during evolution is independent of fire control and cooking

      Directory of Open Access Journals (Sweden)

      Alianda Maira Cornélio

      2016-04-01

      Full Text Available What makes humans unique? This question has fascinated scientists and philosophers for centuries and it is still a matter of intense debate. Nowadays, human brain expansion during evolution has been acknowledged to explain our empowered cognitive capabilities. The drivers for such accelerated expansion remain, however, largely unknown. In this sense, studies have suggested that the cooking of food could be a pre-requisite for the expansion of brain size in early hominins. However, this appealing hypothesis is only supported by a mathematical model suggesting that the increasing number of neurons in the brain would constrain body size among primates due to a limited amount of calories obtained from diets. Here, we show, by using a similar mathematical model, that a tradeoff between body mass and the number of brain neurons imposed by dietary constraints during hominin evolution is unlikely. Instead, the predictable number of neurons in the hominin brain varies much more in function of foraging efficiency than body mass. We also review archeological data to show that the expansion of the brain volume in the hominin lineage is described by a linear function independent of evidences of fire control, and therefore, thermal processing of food does not account for this phenomenon. Finally, we report experiments in mice showing that thermal processing of meat does not increase its caloric availability in mice. Altogether, our data indicate that cooking is neither sufficient nor necessary to explain hominin brain expansion.

    4. Human Brain Expansion during Evolution Is Independent of Fire Control and Cooking.

      Science.gov (United States)

      Cornélio, Alianda M; de Bittencourt-Navarrete, Ruben E; de Bittencourt Brum, Ricardo; Queiroz, Claudio M; Costa, Marcos R

      2016-01-01

      What makes humans unique? This question has fascinated scientists and philosophers for centuries and it is still a matter of intense debate. Nowadays, human brain expansion during evolution has been acknowledged to explain our empowered cognitive capabilities. The drivers for such accelerated expansion remain, however, largely unknown. In this sense, studies have suggested that the cooking of food could be a pre-requisite for the expansion of brain size in early hominins. However, this appealing hypothesis is only supported by a mathematical model suggesting that the increasing number of neurons in the brain would constrain body size among primates due to a limited amount of calories obtained from diets. Here, we show, by using a similar mathematical model, that a tradeoff between body mass and the number of brain neurons imposed by dietary constraints during hominin evolution is unlikely. Instead, the predictable number of neurons in the hominin brain varies much more in function of foraging efficiency than body mass. We also review archeological data to show that the expansion of the brain volume in the hominin lineage is described by a linear function independent of evidence of fire control, and therefore, thermal processing of food does not account for this phenomenon. Finally, we report experiments in mice showing that thermal processing of meat does not increase its caloric availability in mice. Altogether, our data indicate that cooking is neither sufficient nor necessary to explain hominin brain expansion.

    5. ABOUT UN, UFAK AND UŞAK WORDS UN, UFAK VE UŞAK KELİMELERİ ÜZERİNE

      Directory of Open Access Journals (Sweden)

      Ayşe İLKER

      2011-01-01

      Full Text Available “un”, “ufak” and “uşak” words are the oldest words of Turkish in this article, the examples in historical and modernominal documents have been studied, progressing and creating process of this is stated. The ‘un’ word was used as a word with long vowels in the history and today in some dialects. The ‘uşak’ and ‘Ufak’ words were used in the meaning of ‘küçük’ both in historical and modern labels and with interesting derivatives and handiadyoins different meanings were made. By giving examples from the text, the derivation course and meaning evolution were suggested. Bu makalede, Türkçenin en eski kelimelerinden biri olan “un” ve bu kelimenin köküyle ilgili olduğunu düşündüğümüz “ufak” ve “uşak” kelimelerinin tarihî ve çağdaş Türkçe yazılı belgelerdeki örneklerine dayanılarak, gelişme ve türeme seyri anlatılmaktadır. “Un” kelimesi, tarihî dönemde ve bugünkü bazı lehçelerde uzun ünlülü olarak kullanılmıştır. Ufak ve uşak kelimeleri ise, hem tarihî hem çağdaş yazılı belgelerde “küçük” anlamında kullanılmış ve değişik türevler ve ikilemelerle farklı anlamlar oluşturmuştur. Metinlerden örnekler verilerek, bu kelimelerim türeme seyri ve anlam gelişmeleri gösterilmiştir.

    6. Thermophysical Properties of Matter - the TPRC Data Series. Volume 13. Thermal Expansion - Nonmetallic Solids

      Science.gov (United States)

      1977-01-01

      topography of the state of knowledge on the thermal expansion of nonmetallic solids. We believe there is also much food for reflec- West Lafayette...34 Lithium Silicates ......... 713 209 Magnesium Metasilicate MgSiO. .. ......... 715 210 Magnesium Orthosilicate Mg2 SiO . . . . . . . . . . . . 718 211...Antiferromagnetism of Praseodymium," Phys. Rev. Letters, 12(20), 553-5, 1964. 66. Goode, J.M., "Phase Transition Temperature of Polonium ,"J. Chem. Phys., 26(5), 1269

    7. Farklı Tüy Dökümü Yöntemlerinin ve Tüy Dökümü Sonrası Karma Yeme Üzüm Posası Katılmasının Performans, Yumurta Kalitesi ve Yumurta Lipid Peroksidasyonuna Etkisi

      OpenAIRE

      KARA, K.; GÜÇLÜ, B. KOCAOĞLU

      2014-01-01

      Sunulan çalışma, kekliklerde faringeal ve laringeal bölgenin makroskobik ve mikroskobik özellikleri ile bu bölümlerdeki bezlerin histokimyasal özelliklerini detaylı bir şekilde tanımlamak için planlanmıştır. Çalışmada 5 dişi ve 5 erkek olmak üzere toplam 10 adet erişkin ve sağlıklı kınalı keklik kullanıldı. Eter anastezisi altında dil ile beraber farinks ve larinks total olarak diseke edildi ve dokular rutin histolojik işlemleri takiben parafinde bloklandı. Kınalı keklikte anatomik olarak glo...

    8. Ret ve İnkârın Kıskacındaki Nihilist Karakterler: Bazarov ve Suat The Nihilist Characters surrounded by Denial and Denegation: Bazarov and Suat

      Directory of Open Access Journals (Sweden)

      Mustafa AYDEMİR

      2013-09-01

      Full Text Available Nihilism which means the loss of the importance of values supports the idea that the man should use the innate instincts which he has. Only through this way will man be able to return to his origin getting rid of the ethical values and authorities of the society. Nihilism, expressing the way of thought in which the emotions of meaninglessness, emptiness and nonbeing is a life-style which accompanies a spiritual condition which appears when the values and ideals people depend on don’t perform their duties.Nihilism which first was used in Germany the first time was pointed out in the middle of the 19th century in Russia, is a philosophical approach which became widespread with Schopenhauer and finally became systemized with Nietzsche. When the faith of the authors who were influenced by Positivism was scattered they found themselves in Nihilism which they saw as a shelter. Turgenyev in Russian Literature and Tanpınar in Turkish literature utilizes such characters in their novels.In this study, the experiences of individuals who suffer similar problems with the society have been emphasized. Bazarov and Suat who differ in personality, view of world and behaviors are hostile to both themselves and others with the influence of Nihilism. They make the novel a nightmare with their atheistical and rebellious feature. They prefer the matter instead of spirit, absence instead of existence. First the description of Nihilism, its features and its origin has been mentioned then some information about Babalar ve Oğullar by Turgenyev and the novel Huzur by Tanpınar and their eras have been given. The Nihilist features of Bazarov and Suat in these novels have been gathered under specific titles, similar and differences have been pointed out. In the conclusion part, general overview of the study has been made. Değerlerin önemini kaybetmesi anlamına gelen Nihilizm, insanın doğuştan getirdiği içgüdülerini kullanması gerektiğini savunur.

    9. National and University Library of Bosnia and Herzegovina-in Sarajevo Its Fate and Prospects for Revival Saraybosna'daki Bosna-Hersek Ulusal ve Üniversite Kütüphanesi Yazgısı Ve Yeniden Kurulması İle İlgili Beklent

      Directory of Open Access Journals (Sweden)

      Enes Kuyumcic

      1994-06-01

      Full Text Available The National and University Library of Bosnia and Herzegovina was destructed during a bombardment in 1992. The Library has lost very many valuable irreplaceable materials together with its catalogue. The Library was a legal depository since 1945 and it had also become a university library in 1957. Its collections included works in many languages reflecting the multicultural character of Bosnia, rare books, archive materials, and scientific books and journals. The Library used to offer information services and used IT in its work over the last ten years. It was a focal point for library and information reserach and provided guidance and supervision to other libraries in Bosnia and Herzegovina. International assistance is required for the revival of the Library and UNESCO has started a programme. The National and University Library Bosnia and Herzegovina (NUB BiH in Sarajevo was destroyed during the night of 25 August 1992. The precious collections of books, archival material and periodicals representing the memory of many generations perished during the bombardment. The Library Catalogue together with an irreplaceable collection of journals, published since the middle of the 19th Century in Bosnia and Herzegovina and other parts of former Yugoslavia, were also lost. Only a small portion of the Library holdings was saved and is now housed in five different lo cations within the city. The written records in various languages and scripts were witness to the multi-cultural, multiethnic ans multireligious character of Bosnia and Herzegovina. The NUBBiH housed ca. 2 Million volumes and other items including ca. 6.000 periodicals most of which were catalogued according to the international bibliographic description standards. The Automated Library Catalogue had been started a few years ago before the war, and the staff was provided with training in modern technology and carried out library and information research. 1992 yılında bir bombard

    10. Yatarak fizyoterapi alan hastaların yaşam kaliteleri ve maliyet analizi

      OpenAIRE

      AKTAŞ, İlknur; KAPTANOĞLU YILDIRIM, Ayşegül; ÜNLÜ ÖZKAN, Feyza; YILMAZ KAYSIN, Meryem; ŞİLTE, Ayşe Duygu

      2015-01-01

      Amaç: Lokomotor sistem sorunları nedeniyle yatarak fizyoterapi alan hastaların yaşam kaliteleri ve maliyet analizlerini ortaya koymaktır. Hastalar ve Yöntem: Yatarak fizyoterapi alan olguların demografik verileri kaydedildi ve 15 D yaşam kalite sorgulaması yapıldı. Maliyetleri hesaplandı. Yaşam kalitesi ölçeği verilerini kullanarak hesaplanan, kaliteye ayarlanmış yaşam yılı (KAYY) sayısını kullanarak ekonomik analiz yapılmıştır. Bulgular: Doksan üç olgunun 75’i (%80,64) kadın, 18’i (%19,35) e...

    11. Sanayi 4.0 ve Türkiye Ekonomisi Açısından Etkileri

      OpenAIRE

      AYDEMİR, Halit

      2018-01-01

      Bu çalışmada Sanayi 4.0’ın küresel dünya ekonomisi ve Türkiye ekonomisi üzerindeki etkileri, avantaj ve dezavantajları, Sanayi 4.0’ın diğer devrimlerle olan bağı ele alınmaktadır. Bu çerçevede Türkiye için Sanayi 4.0 gelişim sürecinde izlenmesi gereken bir yol haritasının çizilmesi amaçlanmıştır. Yöntemsel olarak ülkeler ve yıllar arası karşılaştırmalı analizler kullanılmıştır.

    12. TURIST ÇEKICILIKLERI VE TURIST AKIŞI ARASINDAKI ILIŞKILERIN MEKÂNSAL BAĞIMLILIĞA DAYALI OLARAK INCELENMESI

      OpenAIRE

      Karagöz Yüncü, Deniz; Mert Kantar, Yeliz; Günay Aktaş, Semra; Sezerel, Hakan

      2017-01-01

      Bu çalışmada, turist çekicilikleri ve turist akışı arasındaki ilişkilermekansal bağımlılığa dayalı olarak incelenerek farklı bir yaklaşımlaoluşturulmuştur. Çalışmada Bursa, Eskişehir ve Bilecik bölgesinde yer alan 39ilçede turist çekicilikleri ve yerli/yabancı turistlerin geceleme sayılarınailişkin ikincil veriler kullanılmıştır. Verilerin analizi için içerik analizi,haritalama analizi, Local ve Global Moran’s I otokorelasyon istatistikleri,klasik regresyon ve mekansal hata modelleri kullanıl...

    13. Ultra-low thermal expansion realized in giant negative thermal expansion materials through self-compensation

      OpenAIRE

      Fei-Ran Shen; Hao Kuang; Feng-Xia Hu; Hui Wu; Qing-Zhen Huang; Fei-Xiang Liang; Kai-Ming Qiao; Jia Li; Jing Wang; Yao Liu; Lei Zhang; Min He; Ying Zhang; Wen-Liang Zuo; Ji-Rong Sun

      2017-01-01

      Materials with zero thermal expansion (ZTE) or precisely tailored thermal expansion are in urgent demand of modern industries. However, the overwhelming majority of materials show positive thermal expansion. To develop ZTE or negative thermal expansion (NTE) materials as compensators has become an important challenge. Here, we present the evidence for the realization of ultra-low thermal expansion in Mn–Co–Ge–In particles. The bulk with the Ni2In-type hexagonal structure undergoes giant NTE o...

    14. Prebiyotiklerin Probiyotik Bakterilerin Gelişmesi ve Asitleştirme Aktiviteleri Üzerine Etkileri (İngilizce

      Directory of Open Access Journals (Sweden)

      Ayla Şener Mumcu

      2015-02-01

      Full Text Available Bu çalışmada altı adet ticari prebiyotik maddenin in vitro koşullarda iki adet Lactobacillus acidophilus suşu ve iki adet Bifidobacterium spp. suşunun gelişme ve asitleştirme aktivitesi üzerindeki etkileri araştırılmıştır. Prebiyotik olarak frukto-oligosakkarit, inulin, galakto-oligosakkarit, soya fasulyesi oligosakkariti, ksilo-oligosakkarit ve laktuloz kullanılmıştır. Prebiyotikler üç farklı konsantrasyonda denenmiştir. Probiyotik bakterilerin gelişme ve asitleştirme aktivitesi üzerindeki etkileri prebiyotik çeşidine ve konsantrasyonuna bağlı olarak değişim göstermiştir. Genel olarak, prebiyotik konsantrasyonu arttıkça, probiyotik bakteri suşlarının gelişme performansı ve asitleştirme aktivitesinde artışlar meydana gelmiştir. L. acidophilus türündeki suş farklılığı, suşların gelişme performansı ve asitleştirme aktivitesi üzerinde önemli bir etki yaratmamıştır. Buna karşılık Bifidobacterium cinsindeki tür farklılığının bu yönlerdeki etkisi önemli bulunmuştur ( P<0.05. Araştırma sonuçları, bir probiyotik bakteri suşunun iyi bir gelişme ve asitleştirme performansı gösterebilmesi için ona uygun bir prebiyotik madde seçilmesinin gerekliliğine işaret etmektedir.

    15. İbrahim Müteferrika ve İlk Türk Matbaası

      Directory of Open Access Journals (Sweden)

      Şerif Korkmaz

      2015-11-01

      Full Text Available Osmanlı devletinin Avrupa'dan bilinçli iktibasların yapıldığı ilk dönem 1718-1730 yılları arasındaki "Lale Devri" dir. bu dönemde özellikle eğitimlerini incelemek için Avrupa'nın pek çok ülkesine elçiler gönderilmiştir. Fakat bu devrin en büyük ve en tesirli yeniliği İbrahim Müteferrika ve Sadi Efendi'nin birlikte açtıkları matbaadır. Makalede İbrahim Müteferrikanın kimliği ve fikirleri hakkında bilgi verilmektedir. Onun etkisinin sadece  matbaa ile sınırlı olmadığı, Osmanlı için yeni sayılabilecek ilimlerle ilgili eserleri basarak Avrupa'nın Rönesans'ından ilk haberleri verdiği vurgulanmaktadır.

    16. MACULAR CHOROIDAL VOLUME CHANGES AFTER INTRAVITREAL BEVACIZUMAB FOR EXUDATIVE AGE-RELATED MACULAR DEGENERATION.

      Science.gov (United States)

      Palkovits, Stefan; Seidel, Gerald; Pertl, Laura; Malle, Eva M; Hausberger, Silke; Makk, Johanna; Singer, Christoph; Osterholt, Julia; Herzog, Sereina A; Haas, Anton; Weger, Martin

      2017-12-01

      To evaluate the effect of intravitreal bevacizumab on the macular choroidal volume and the subfoveal choroidal thickness in treatment naïve eyes with exudative age-related macular degeneration. The macular choroidal volume and the subfoveal choroidal thickness were measured using enhanced depth imaging optical coherence tomography. After a screening examination, each patient received 3 monthly intravitreal injections of 1.25 mg bevacizumab. One month after the third injection was a final assessment. Forty-seven patients with a mean age of 80 ± 6.4 years were included. The macular choroidal volume decreased significantly from median 4.1 mm (interquartile range 3.4-5.9) to median 3.9 mm (interquartile range 3.1-5.6) between the baseline and final examination (difference -0.46 mm, 95% confidence interval: -0.57 to 0.35, P macular choroidal volume at baseline and subfoveal choroidal thickness at baseline were not associated with the response to treatment. The macular choroidal volume and the subfoveal choroidal thickness decreased significantly after 3 monthly bevacizumab injections for exudative age-related macular degeneration.

    17. Thermal expansion of granite rocks

      International Nuclear Information System (INIS)

      Stephansson, O.

      1978-04-01

      The thermal expansion of rocks is strongly controlled by the thermal expansion of the minerals. The theoretical thermal expansion of the Stripa Granite is gound to be 21 . 10 -6 [deg C] -1 at 25 deg C and 38 . 10 -6 [deg C] -1 at 400 deg C. The difference in expansion for the rock forming minerals causes micro cracking at heating. The expansion due to micro cracks is found to be of the same order as the mineral expansion. Most of the micro cracks will close at pressures of the order of 10 - 20 MPa. The thermal expansion of a rock mass including the effect of joints is determined in the pilot heater test in the Stripa Mine

    18. Ni VE Cu İLE ALAŞIMLANDIRILMIŞ KÜRESEL GRAFİTLİDÖKME DEMİRLERİN İŞLENEBİLİRLİĞİNİN KESME KUVVETLERİ VE YÜZEY KALİTELERİ AÇISINDAN DEĞERLENDİRİLMESİ

      Directory of Open Access Journals (Sweden)

      Yücel AŞKUN

      2003-02-01

      Full Text Available Diğer dökme demirlerle karşılaştırıldığında, Küresel Grafitli Dökme Demirin (KGDD yüksek süneklik, çekme dayanımı ve tokluğunun yanında işlenebilirliği nispeten düşüktür. Bununla birlikte; bir çelik parçanın yerine küresel grafitli dökme demir kullanıldığı zaman daha iyi işlenebilirlik en önemli kazanç olarak düşünülmelidir. Bu çalışma, değişik oranlarda Ni ve Cu ile alaşımlandırılmış küresel grafitli dökme demirlerin kesme kuvvetleri ve yüzey pürüzlülüğü üzerine onların mikroyapı ve mekanik özelliklerinin etkilerini belirlemek için yapılan işlenebilirlik testlerinin sonuçlarını göstermektedir. Değişik oranlarda nikel ve bakır ile alaşımlandırılmış altı farklı küresel grafitli dökme demire işlenebilirlik testleri uygulanmış ve onların işlenebilirlikleri kesme kuvvetleri ve yüzey pürüzlülük temel kriterleri üzerine dayanarak incelenmiştir. Sonuçlar; numunelerin daha önceden belirlenmiş olan mikroyapı ve mekanik özelliklerine göre değerlendirilmiştir. Bütün kriterlere dayanarak en iyi sonuçlar, % 0.7 Ni ve % 0.7 Cu ilave edilmiş numunede gözlenmiştir. Numuneler mekanik özellikleri açısından değerlendirildiğinde, % 1 Ni ve % 0.65 Cu ilave edilmiş numunede sağlanacağı görülmektedir.

    19. Study of the multifragmentation in central collisions of the system: {sup 129}Xe + {sup nat}Sn between 32 and 50 MeV/A: measurement of collective expansion energy and of freeze-out volume; Etude de la multifragmentation dans les collisions centrales pour le systeme {sup 129}Xe + {sup nat}Sn entre 32 et 50 MeV/A: mesure de l`energie collective d`expansion et du volume de freeze-out

      Energy Technology Data Exchange (ETDEWEB)

      Salou, S

      1997-12-05

      The multifragmentation of the nuclear system formed in the central collisions of the Xe+Sn reaction between 32 and 50 MeV/A has been studied with the INDRA detector. A tensorial analyse is used to select central collisions. An important part of the charge (about 85 %) is isotropically emitted. The charge partitions have the characteristics of a simultaneous multiple fragment emission. The shape of the fragment kinetic energy distributions together with the reduced velocity correlation functions indicate that the fragmentation is a simultaneous process that occurs at low density. A comparison between the experimental data and predictions of the statistical multifragmentation model of Copenhagen (SMM) shows that charge partitions agree with the hypothesis of a thermodynamical equilibrium, whereas, kinetic observables are more constraining to the model and difficult to reproduce. However, fragments correlation functions are used in order to extract the freeze-out volume and the collective radial energy. At 50 MeV/A, the freeze-out volume is estimated to be 2.7 times the normal volume. It decreases with incident energy to be nearly twice the normal volume at 32 MeV/S. The collective energy evolves from 0 to 1.3 MeV/A with the bombarding energy. This expansion is not purely thermal and originates probably from a dynamical compression developed in the early stage of the collision. (author) 88 refs.

    20. Capturing Human Naïve Pluripotency in the Embryo and in the Dish.

      Science.gov (United States)

      Zimmerlin, Ludovic; Park, Tea Soon; Zambidis, Elias T

      2017-08-15

      Although human embryonic stem cells (hESCs) were first derived almost 20 years ago, it was only recently acknowledged that they share closer molecular and functional identity to postimplantation lineage-primed murine epiblast stem cells than to naïve preimplantation inner cell mass-derived mouse ESCs (mESCs). A myriad of transcriptional, epigenetic, biochemical, and metabolic attributes have now been described that distinguish naïve and primed pluripotent states in both rodents and humans. Conventional hESCs and human induced pluripotent stem cells (hiPSCs) appear to lack many of the defining hallmarks of naïve mESCs. These include important features of the naïve ground state murine epiblast, such as an open epigenetic architecture, reduced lineage-primed gene expression, and chimera and germline competence following injection into a recipient blastocyst-stage embryo. Several transgenic and chemical methods were recently reported that appear to revert conventional human PSCs to mESC-like ground states. However, it remains unclear if subtle deviations in global transcription, cell signaling dependencies, and extent of epigenetic/metabolic shifts in these various human naïve-reverted pluripotent states represent true functional differences or alternatively the existence of distinct human pluripotent states along a spectrum. In this study, we review the current understanding and developmental features of various human pluripotency-associated phenotypes and discuss potential biological mechanisms that may support stable maintenance of an authentic epiblast-like ground state of human pluripotency.

    1. Surface-Based Regional Homogeneity in First-Episode, Drug-Naïve Major Depression: A Resting-State fMRI Study

      Directory of Open Access Journals (Sweden)

      Hui-Jie Li

      2014-01-01

      Full Text Available Background. Previous volume-based regional homogeneity (ReHo studies neglected the intersubject variability in cortical folding patterns. Recently, surface-based ReHo was developed to reduce the intersubject variability and to increase statistical power. The present study used this novel surface-based ReHo approach to explore the brain functional activity differences between first-episode, drug-naïve MDD patients and healthy controls. Methods. Thirty-three first-episode, drug-naïve MDD patients and 32 healthy controls participated in structural and resting-state fMRI scans. MDD patients were rated with a 17-item Hamilton Rating Scale for Depression prior to the scan. Results. In comparison with the healthy controls, MDD patients showed reduced surface-based ReHo in the left insula. There was no increase in surface-based ReHo in MDD patients. The surface-based ReHo value in the left insula was not significantly correlated with the clinical information or the depressive scores in the MDD group. Conclusions. The decreased surface-based ReHo in the left insula in MDD may lead to the abnormal top-down cortical-limbic regulation of emotional and cognitive information. The surface-based ReHo may be a useful index to explore the pathophysiological mechanism of MDD.

    2. Bezelyelerde Klorofil Degradasyonu ve Renk Kaybı Üzerine Isıl İşlemin Etkisi (İngilizce

      Directory of Open Access Journals (Sweden)

      Hande Selen Erge

      2015-02-01

      Full Text Available Bezelyelerde klorofilin termal degradasyon kinetiği ve görünür yeşil renkteki kayıp 70°, 80°, 90° ve 100 °C’de araştırılmıştır. Klorofil a ve klorofil b’nin parçalanması birinci dereceden bir kinetik model izlemektedir. Tristimulus kolorimetresi ile ölçülen -a, -a/b ve h (hue değerlerindeki değişim ile ortaya konulan görünür yeşil renkteki kayıp da birinci dereceden reaksiyona uymaktadır. Klorofil a ve b için aktivasyon enerjileri sırasıyla 47.78 and 26.77 kJ mol-1olarak belirlenirken; -a, -a/b ve h değerleri için aktivasyon enerjileri 49.75, 56.04 and 55.06 kJ mol-1 olarak saptanmıştır.

    3. Peskütenin Kimyasal ve Mikrobiyolojik Özellikleri Üzerine bir Araştırma

      Directory of Open Access Journals (Sweden)

      Ahmet Kurt

      2015-02-01

      Full Text Available Bu araştırmada Sivas ili ve çevresinden şansa bağlı olarak alınan 14 adet Pesküten örneği üzerinde kimyasal ve mikrobiyolojik araştırmalar yapılmıştır. Belirlenen değerler ortalama olarak şöyledir: Kurumaddede %30.96, su %69.04, yağ %3.66, yağsız kurumadde %27.30, toplam kül %4.92, kurumaddede kül %15.95, kurumaddede tuz %12.18, saf kül %1.13, protein %22.08, şeker ve benzerleri %0.295 ve asitlik derecesi 83.90 SH olmuştur. Bunun yanında ortalama mikrobiyolojik içerik; toplam bakteri sayısı 3.735x106/g, koliform bakteri sayısı 5.69x104/g, maya ve küf sayısı 1.398x104/g, laktik bakteri sayısı 1.997x106/g, proteolitik bakteri sayısı, 12.34x104/g ve lipolitik bakteri sayısı 10.14x104/g olarak belirlenmiştir.

    4. Analysis of Naïve Bayes Algorithm for Email Spam Filtering across Multiple Datasets

      Science.gov (United States)

      Fitriah Rusland, Nurul; Wahid, Norfaradilla; Kasim, Shahreen; Hafit, Hanayanti

      2017-08-01

      E-mail spam continues to become a problem on the Internet. Spammed e-mail may contain many copies of the same message, commercial advertisement or other irrelevant posts like pornographic content. In previous research, different filtering techniques are used to detect these e-mails such as using Random Forest, Naïve Bayesian, Support Vector Machine (SVM) and Neutral Network. In this research, we test Naïve Bayes algorithm for e-mail spam filtering on two datasets and test its performance, i.e., Spam Data and SPAMBASE datasets [8]. The performance of the datasets is evaluated based on their accuracy, recall, precision and F-measure. Our research use WEKA tool for the evaluation of Naïve Bayes algorithm for e-mail spam filtering on both datasets. The result shows that the type of email and the number of instances of the dataset has an influence towards the performance of Naïve Bayes.

    5. Organik Tavukçulukta Mera Kompozisyonu, Besleme ve Barındırma Teknikleri

      Directory of Open Access Journals (Sweden)

      Hasan Eleroğlu

      2014-01-01

      Full Text Available Dünya’daki gelişmelere paralel olarak, Türkiye’de de organik tavukçuluk sektöründe gelişmeler yaşanmaktadır. Son yıllarda artan taleplerin karşılanması amacıyla üretim artışı söz konusu olup, yeni organik işletmeler sayısında artış gözlenmektedir. Hayvanların besin maddesi ihtiyaçlarının belli bir kısmının meradan sağlanması için yerel bitkilerden yararlanılarak, uygun mera kompozisyonunun ekonomik üretimi destekleyecek şekilde oluşturulması gerekmektedir. Bununla birlikte, çevre koşulları ve barındırma tekniklerinin kanatlının performansı, sağlığı, refahı, ürün kalitesi üzerine etkisi bulunmaktadır. Bu nedenle çevre koşulları ve barındırma tekniklerinin, yerel koşullara uyumlu ve organik standartları sağlayacak şekilde düzenlenmesi gerekmektedir. Hayvanların günlük besin maddesi ihtiyaçlarının dengeli olarak karşılanmasında, hayvanların severek tükettikleri buğdaygil ve baklagil yem bitkileri yanında otlatmaya dayanıklı endemik bitkilerden oluşan karışımlardan yararlanılarak, mera kompozisyonu belirlenmelidir. Sabit ve taşınır barındırma sistemlerinde kullanılacak malzemelerin organik üretim standartlarına uygun olmalıdır. Kümes içi ve mera donanımları arasında bulunan yemlik ve sulukların organizasyonunda yöresel iklim koşulları dikkate alınmalı, özellikle ısıtma sistemlerinde aydınlatma yapmayan ısı kaynaklarının seçilmesi gerekmektedir. Yabani kuş ve yırtıcı hayvanlardan korunma amaçlı geliştirilen sistemler üzerinde durulmalı, ürün elde etme ve değerlendirme aşamasında, ürün kalitesinin maksimum düzeyde korunabileceği uygulamalar üzerinde durulmalıdır. Bu çalışmada, organik tavukçuluk üzerinde durularak, örnek olarak Sivas koşullarında organik etlik piliç üretiminde kullanılmak üzere oluşturulan mera kompozisyonu ile birlikte organik tavuk yetiştirmede kullanılan barındırma sistemi

    6. Fragmentation, dissipative expansion, and freeze-out in medium energy heavy-ion collisions

      International Nuclear Information System (INIS)

      Gross, D.H.E.; Li Baoan; DeAngelis, A.R.

      1992-01-01

      The collision dynamics of 96 Mo + 96 Mo at 55 A MeV is simulated by solving numerically the Boltzmann-Uehling-Uhlenbeck (BUU) transport equation for the one-body phase-space distribution-function of nucleons with and without Coulomb interaction. A scatter-plot of the one-body density distribution shows an initial compression, subsequent homogeneous expansion, a breaking into ''fragments'', a very slow creeping expansion up to a freeze-out and in the case of included Coulomb-interaction a Coulomb-explosion. In the calculation which included Coulomb-interaction the overall shape of the ensemble of dense fragments is spherical. The fragments are created over the entire volume of the dense part of the source and not at the surface only. In the simulation without Coulomb interaction a doughnut-like shape may develop. (orig.)

    7. KESTANE KABUĞUNUN PİROLİZİ VE ELDE EDİLEN ÜRÜNLERİN KARAKTERİZASYONU

      Directory of Open Access Journals (Sweden)

      Ilknur DEMIRAL

      2015-11-01

      Full Text Available Bu çalışmada kestane kabuğu biyokütle kaynağı olarak seçilmiş ve sabit yataklı reaktörde pirolizi gerçekleştirilmiştir. Deneylerde piroliz sıcaklığı, ısıtma hızı ve sürükleyici gaz akış hızının piroliz ürün verimleri üzerindeki etkileri incelenmiştir. Yapılan deneyler sonucunda en yüksek katran verimine 50 oCdk-1 ısıtma hızı, 400 oC piroliz sıcaklığı ve 150 cm3dk-1 sürükleyici gaz akış hızında %18,70 ile ulaşılmıştır. Çalışmalar sonucunda elde edilen katranın FTIR spektrumu alınmış, elementel analizi gerçekleştirilmiş ve ısıl değeri belirlenmiştir. Katran sütun kromatografisinde hidrokarbon ve polar bileşiklerine ayrılmıştır.  Alifatik alt fraksiyon GC-MS ile karakterize edilmiştir. Ayrıca hammaddenin ve katı ürünün BET yüzey alanları belirlenmiş ve katı ürünün SEM görüntüsü alınmıştır.

    8. Endothelial cell SHP-2 negatively regulates neutrophil adhesion and promotes transmigration by enhancing ICAM-1-VE-cadherin interaction.

      Science.gov (United States)

      Yan, Meiping; Zhang, Xinhua; Chen, Ao; Gu, Wei; Liu, Jie; Ren, Xiaojiao; Zhang, Jianping; Wu, Xiaoxiong; Place, Aaron T; Minshall, Richard D; Liu, Guoquan

      2017-11-01

      Intercellular adhesion molecule-1 (ICAM-1) mediates the firm adhesion of leukocytes to endothelial cells and initiates subsequent signaling that promotes their transendothelial migration (TEM). Vascular endothelial (VE)-cadherin plays a critical role in endothelial cell-cell adhesion, thereby controlling endothelial permeability and leukocyte transmigration. This study aimed to determine the molecular signaling events that originate from the ICAM-1-mediated firm adhesion of neutrophils that regulate VE-cadherin's role as a negative regulator of leukocyte transmigration. We observed that ICAM-1 interacts with Src homology domain 2-containing phosphatase-2 (SHP-2), and SHP-2 down-regulation via silencing of small interfering RNA in endothelial cells enhanced neutrophil adhesion to endothelial cells but inhibited neutrophil transmigration. We also found that VE-cadherin associated with the ICAM-1-SHP-2 complex. Moreover, whereas the activation of ICAM-1 leads to VE-cadherin dissociation from ICAM-1 and VE-cadherin association with actin, SHP-2 down-regulation prevented ICAM-1-VE-cadherin association and promoted VE-cadherin-actin association. Furthermore, SHP-2 down-regulation in vivo promoted LPS-induced neutrophil recruitment in mouse lung but delayed neutrophil extravasation. These results suggest that SHP-2- via association with ICAM-1-mediates ICAM-1-induced Src activation and modulates VE-cadherin switching association with ICAM-1 or actin, thereby negatively regulating neutrophil adhesion to endothelial cells and enhancing their TEM.-Yan, M., Zhang, X., Chen, A., Gu, W., Liu, J., Ren, X., Zhang, J., Wu, X., Place, A. T., Minshall, R. D., Liu, G. Endothelial cell SHP-2 negatively regulates neutrophil adhesion and promotes transmigration by enhancing ICAM-1-VE-cadherin interaction. © FASEB.

    9. Plasmodium vivax sporozoite challenge in malaria-naïve and semi-immune Colombian volunteers

      DEFF Research Database (Denmark)

      Arévalo-Herrera, Myriam; Forero-Peña, David A.; Rubiano, Kelly

      2014-01-01

      induced in naïve and semi-immune volunteers by infected mosquito bites was compared. Methods: Seven malaria-naïve and nine semi-immune Colombian adults (n = 16) were subjected to the bites of 2-4 P. vivax sporozoite-infected Anopheles mosquitoes. Parasitemia levels, malaria clinical manifestations...

    10. Paraziti ve vyjadřování

      Czech Academy of Sciences Publication Activity Database

      Michalec, Vít

      2017-01-01

      Roč. 96, č. 6 (2017), s. 368-368 ISSN 0042-4544 Institutional support: RVO:68378092 Keywords : word jakoby Subject RIV: AI - Linguistics OBOR OECD: Linguistics https://vesmir.cz/cz/casopis/archiv-casopisu/2017/cislo-6/paraziti-ve-vyjadrovani.html

    11. The reexamination of thermal expansion of ferromagnetic superconductors and the pressure differential of its superconducting transition temperature-possible application to UGe2

      International Nuclear Information System (INIS)

      Konno, Rikio; Hatayama, Nobukuni

      2011-01-01

      The temperature dependence of thermal expansion of ferromagnetic superconductors below the superconducting transition temperature T scu of a majority spin conduction band is reexamined. In the previous study [to be published in J. M. Phys. B] the volume differential of the kinetic energy of conduction electrons is constant. However, in this study the volume differential of the kinetic energy of conduction electrons is inconstant. The superconducting gap of the majority spin conduction band used in this study has a line node. It is appropriate to UGe 2 . The pressure differential of its superconducting transition temperature is also investigated. We find that the thermal expansion coefficient has the divergence at the superconducting transition temperature. The thermodynamic Grueneisen's relation is satisfied.

    12. Parameters affecting the tidal volume during expiratory abdominal compression in patients with prolonged tracheostomy mechanical ventilation.

      Science.gov (United States)

      Morino, Akira; Shida, Masahiro; Tanaka, Masashi; Sato, Kimihiro; Seko, Toshiaki; Ito, Shunsuke; Ogawa, Shunichi; Takahashi, Naoaki

      2015-07-01

      [Purpose] The aim of this study was to clarify physical parameters affecting the tidal volume during expiratory abdominal compression in patients with prolonged tracheostomy mechanical ventilation. [Methods] Eighteen patients with prolonged mechanical ventilation were included in this study. Expiratory abdominal compression was performed on patients lying in a supine position. The abdomen above the navel was vertically compressed in synchronization with expiration and released with inspiration. We measured the tidal volume during expiratory abdominal compression. [Results] The mean tidal volume during expiratory abdominal compression was higher than that at rest (430.6 ± 127.1 mL vs. 344.0 ± 94.3 mL). The tidal volume during expiratory abdominal compression was correlated with weight, days of ventilator support, dynamic compliance and abdominal expansion. Stepwise multiple regression analysis revealed that weight (β = 0.499), dynamic compliance (β = 0.387), and abdominal expansion (β = 0.365) were factors contributing to the tidal volume during expiratory abdominal compression. [Conclusion] Expiratory abdominal compression increased the tidal volume in patients with prolonged tracheostomy mechanical ventilation. The tidal volume during expiratory abdominal compression was influenced by each of the pulmonary conditions and the physical characteristics.

    13. GENÇ PARTİ'Yİ ANLAMAK (Parti, Lider ve Kitle Üzerine Bir Çalısma)

      OpenAIRE

      TÜRK, Hasan Bahadır

      2007-01-01

      Türk, Hasan Bahadır, Genç Parti’yi Anlamak: Parti, Lider ve Kitle Üzerine BirÇalısma, Doktora Tezi, Danısman: Doç.Dr. Aykut Çelebi, 399 s.ÖZETBu çalısmanın amacı; Genç Parti’nin temel yapısal özelliklerine ısık tutmaktır. Çalısma;Genç Parti’yi lider, kadro, parti tipolojisi, ideoloji ve söylem gibi parçalarındanhareketle analiz etmeye ve kitleyle kurdugu iliskiyi tartısmaya odaklanacaktır. Çalısma,üç ana bölümden olusmaktadır. lk iki bölümde Uzanlar’ın genel yapısı, yükselis veçöküs süreci Ge...

    14. Capillary Tube and Thermostatic Expansion Valve Comparative Analysis in Water Chiller Air Conditioning

      Science.gov (United States)

      Wijaya Sunu, Putu; Made Rasta, I.; Anakottapary, Daud Simon; Made Suarta, I.; Cipta Santosa, I. D. M.

      2018-01-01

      The aims of this study to compares the performance characteristics of a water chiller air conditioning simulation equipped with thermostatic expansion valve (TEV) with those of a capillary tube. Water chiller system filled with the same charge of refrigerant. Comparative analyses were performed based on coefficient of performance (COP) and performance parameter of the refrigeration system, carried out at medium cooling load level with the ambient temperature of 29-31°C, constant compressor speed and fixed chilled water volume flowrate at 15 lpm. It was shown that the TEV system showed better energy consumption compared to that of capillary tube. From the coefficient of performance perspective, the thermostatic expansion valve system showed higher COP (± 21.4%) compared to that of capillary tube system.

    15. Türkiye'de Gıda Endüstrisi Kaynaklı Biyokütle ve Biyoyakıt Potansiyeli

      Directory of Open Access Journals (Sweden)

      Ebru Deniz, Gülen Yeşilören, Necla Özdem İşçi

      2015-02-01

      Full Text Available Geliflen teknoloji ve hızlı nüfus artıflının do¤al bir sonucu olarak fosil yakıt kaynaklarının giderekazalması; yenilenebilir ve sürdürülebilir enerji kaynaklarına olan ihtiyacı arttırmıfltır. Son yıllardamevcut enerji kaynaklarına alternatif olarak, ülkelerin sürdürülebilir kalkınmasına olan katkısı sebebiylebiyokütleden elde edilecek enerjiye (biyoyakıta duyulan ilgi artmıfltır. Gıda endüstrisi atıkları oldukçade¤erli biyokütle kaynaklarıdır. Bu makalede Türkiye'deki meyve suyu, bitkisel ya¤ ve et endüstrisiüretim faaliyetleri sırasında ortaya çıkan atık potansiyeli ve bu atıklardan üretilebilecek teorik biyoyakıt(biyogaz, biyoetanol ve biyodizel miktarları hesaplanmıfltır. Bir yılda üretilen meyve suyu, bitkisel ya¤ve et endüstrisi atık miktarları sırasıyla 209.9 bin ton, 111.3 bin ton ve 118 milyon tondur. Bu atıklardan6.9 bin ton biyoetanol, 33.5 bin ton biyodizel ve 25.3 milyar m3biyogaz elde edilebilir

    16. VE-cadherin Y685F knock-in mouse is sensitive to vascular permeability in recurrent angiogenic organs.

      Science.gov (United States)

      Sidibé, Adama; Polena, Helena; Pernet-Gallay, Karin; Razanajatovo, Jeremy; Mannic, Tiphaine; Chaumontel, Nicolas; Bama, Soumalamaya; Maréchal, Irène; Huber, Philippe; Gulino-Debrac, Danielle; Bouillet, Laurence; Vilgrain, Isabelle

      2014-08-01

      Covalent modifications such as tyrosine phosphorylation are associated with the breakdown of endothelial cell junctions and increased vascular permeability. We previously showed that vascular endothelial (VE)-cadherin was tyrosine phosphorylated in vivo in the mouse reproductive tract and that Y685 was a target site for Src in response to vascular endothelial growth factor in vitro. In the present study, we aimed to understand the implication of VE-cadherin phosphorylation at site Y685 in cyclic angiogenic organs. To achieve this aim, we generated a knock-in mouse carrying a tyrosine-to-phenylalanine point mutation of VE-cadherin Y685 (VE-Y685F). Although homozygous VE-Y685F mice were viable and fertile, the nulliparous knock-in female mice exhibited enlarged uteri with edema. This phenotype was observed in 30% of females between 4 to 14 mo old. Histological examination of longitudinal sections of the VE-Y685F uterus showed an extensive disorganization of myometrium and endometrium with highly edematous uterine glands, numerous areas with sparse cells, and increased accumulation of collagen fibers around blood vessels, indicating a fibrotic state. Analysis of cross section of ovaries showed the appearance of spontaneous cysts, which suggested increased vascular hyperpermeability. Electron microscopy analysis of capillaries in the ovary showed a slight but significant increase in the gap size between two adjacent endothelial cell membranes in the junctions of VE-Y685F mice (wild-type, 11.5 ± 0.3, n = 78; and VE-Y685F, 12.48 ± 0.3, n = 65; P = 0.045), as well as collagen fiber accumulation around capillaries. Miles assay revealed that either basal or vascular endothelial growth factor-stimulated permeability in the skin was increased in VE-Y685F mice. Since edema and fibrotic appearance have been identified as hallmarks of initial increased vascular permeability, we conclude that the site Y685 in VE-cadherin is involved in the physiological regulation of capillary

    17. Hydration and blood volume effects on human thermoregulation in the heat: Space applications

      Science.gov (United States)

      Sawka, Michael N.; Gonzalez, Richard R.; Pandolf, Kent B.

      1994-01-01

      Astronauts exposed to prolonged weightlessness will experience deconditioning, dehydration, and hypovolemia which all adversely affect thermoregulation. These thermoregulatory problems can be minimized by several countermeasures that manipulate body water and vascular volumes. USARIEM scientists have extensively studied dehydration effects and several possible countermeasures including hyperhydration, plasma and erythrocyte volume expansion. This paper reviews USARIEM research into these areas.

    18. Change in end-tidal carbon dioxide outperforms other surrogates for change in cardiac output during fluid challenge.

      Science.gov (United States)

      Lakhal, K; Nay, M A; Kamel, T; Lortat-Jacob, B; Ehrmann, S; Rozec, B; Boulain, T

      2017-03-01

      During fluid challenge, volume expansion (VE)-induced increase in cardiac output (Δ VE CO) is seldom measured. In patients with shock undergoing strictly controlled mechanical ventilation and receiving VE, we assessed minimally invasive surrogates for Δ VE CO (by transthoracic echocardiography): fluid-induced increases in end-tidal carbon dioxide (Δ VE E'CO2 ); pulse (Δ VE PP), systolic (Δ VE SBP), and mean systemic blood pressure (Δ VE MBP); and femoral artery Doppler flow (Δ VE FemFlow). In the absence of arrhythmia, fluid-induced decrease in heart rate (Δ VE HR) and in pulse pressure respiratory variation (Δ VE PPV) were also evaluated. Areas under the receiver operating characteristic curves (AUC ROC s) reflect the ability to identify a response to VEVE CO ≥15%). In 86 patients, Δ VE E'CO2 had an AUC ROC =0.82 [interquartile range 0.73-0.90], significantly higher than the AUC ROC for Δ VE PP, Δ VE SBP, Δ VE MBP, and Δ VE FemFlow (AUC ROC =0.61-0.65, all P  1 mm Hg (>0.13 kPa) had good positive (5.0 [2.6-9.8]) and fair negative (0.29 [0.2-0.5]) likelihood ratios. The 16 patients with arrhythmia had similar relationships between Δ VE E'CO2 and Δ VE CO to patients with regular rhythm ( r 2 =0.23 in both subgroups). In 60 patients with no arrhythmia, Δ VE E'CO2 (AUC ROC =0.84 [0.72-0.92]) outperformed Δ VE HR (AUC ROC =0.52 [0.39-0.66], P AUC ROC =0.73 [0.60-0.84], P =0.21). In the 45 patients with no arrhythmia and receiving ventilation with tidal volume AUC ROC =0.86 [0.72-0.95] vs 0.66 [0.49-0.80], P =0.02. Δ VE E'CO2 outperformed Δ VE PP, Δ VE SBP, Δ VE MBP, Δ VE FemFlow, and Δ VE HR and, during protective ventilation, arrhythmia, or both, it also outperformed Δ VE PPV. A value of Δ VE E'CO2 >1 mm Hg (>0.13 kPa) indicated a likely response to VE. © The Author 2017. Published by Oxford University Press on behalf of the British Journal of Anaesthesia. All rights reserved. For Permissions, please email: journals.permissions@oup.com

    19. Isıl İşlem Uygulanmış Et ve Et Ürünlerinde Heterosiklik Aromatik Aminler

      Directory of Open Access Journals (Sweden)

      Fatih Öz

      2015-02-01

      Full Text Available 1977 yılında Japon bilim adamları, kızartılmış et ve balık ürünlerinden Heterosiklik Aromatik Amin (HAA olarak sınıflandırdıkları yüksek oranda toksik yeni bir grup bilesikler belirlemişlerdir. HAA’ler balık ve et gibi protein bakımından zengin gıdaların 150 °C’nin üzerindeki sıcaklıklarda pişirilmesi esnasında oluşan mutajenik ve/veya kanserojenik bileşiklerdir. Bu bileşikler aminoasitler ve karbonhidratlar ile kreatin veya kreatininin reaksiyon ürünleridir. Bu çalışmada HAA’lerin oluşumu, prekürsörleri, oluşum seviyelerinin azaltılması ve analiz metotları ile ilgili araştırmalar derlenmiştir. Gıda mutajenleri ile karşılaştırıldığında HAA’lerin aflatoksin B1 den 100 kat, benzo[a]pyrene den ise 2000 kat daha fazla mutajenik oldukları belirtilmiştir. Güçlü mutajen olan bu bileşikleri içeren gıdaların birçok ülkede yaygın olarak tüketilmesi ve epidemiyolojik çalışmaların bu tür gıdaları fazlaca tüketen ülkelerde kanser oranının çok daha yüksek olduğunu belirtmesinden dolayı konu dünya çapında büyük öneme sahiptir. Günümüze kadar, gıdalardan ve model sistemlerden 25’i aşkın HAA izole edilmiştir. HAA’ler genelde ısıl işlem uygulanmış et ve et ürünlerinde bulunurlar. HAA’lerin konsantrasyonları ısıl işlem gören ürünün tipi, pişirme sıcaklığı ve süresi,  pişirme ekipman ve metodu, pH ve su aktivitesi gibi fiziksel faktörler ile karbonhidratlar, serbest aminoasitler ve kreatin gibi kimyasal faktörlere bağlıdır. Ayrıca, ısı ve kütle transferi, yağlar, yağ oksidasyonu ve antioksidanların HAA’lerin konsantrasyonuna etki ettiği saptanmıştır.

    20. Partial molar volume of mefenamic acid in alcohol at temperatures between T=293.15 and T=313.15 K

      OpenAIRE

      Iqbal, Muhammad J.; Siddiquah, Mahrukh

      2006-01-01

      Apparent molar volume (Vphi), partial molar volume (V), solute-solute interaction parameter (Sv), partial molar expansivity (E(0)2) and isobaric thermal expansion coefficient (alpha2) of mefenamic acid in six different organic solvents namely, methanol, ethanol, 1-propanol, 2-propanol, 1-butanol, and 2-butanol, have been calculated from the measured solution densities over a temperature range of T=293.15 and T=313.15±0.1K. The solution densities were measured by an automated vibrating tube de...

    1. Densities and volume properties of (water + tert-butanol) over the temperature range of (274.15 to 348.15) K at pressure of 0.1 MPa

      International Nuclear Information System (INIS)

      Egorov, Gennadiy I.; Makarov, Dmitriy M.

      2011-01-01

      The densities of {water (1) + tert-butanol (2)} binary mixture were measured over the temperature range (274.15 to 348.15) K at atmospheric pressure using 'Anton Paar' digital vibrating-tube densimeter. Density measurements were carried out over the whole concentration range at (308.15 to 348.15) K. The following volume parameters were calculated: excess molar volumes and thermal isobaric expansivities of the mixture, partial molar volumes and partial molar thermal isobaric expansivities of the components. Concentration dependences of excess molar volumes were fitted with Redlich-Kister equation. The results of partial molar volume calculations using four equations were compared. It was established that for low alcohol concentrations at T ≤ 208 K the inflection points at x 2 ∼ 0.02 were observed at concentration dependences of specific volume. The concentration dependences of partial molar volumes of both water and tert-butanol had extremes at low alcohol content. The temperature dependence of partial molar volumes of water had some inversion at x 2 ∼ 0.65. The temperature dependence of partial molar volumes of tert-butanol at infinite dilution had minimum at ∼288 K. It was discovered that concentration dependences of thermal isobaric expansivities of the mixture at small alcohol content and low temperatures passed through minimum.

    2. Punica granatum L. Çekirdek ve Kabuk Ekstrelerinin Antioksidan Aktiviteleri

      OpenAIRE

      DEMİR, Hülya

      2008-01-01

      Bu çalışmada, Punica granatum L.(Punicaceae) "Nar", meyve çekirdeği ile kabuk ekstraklarının antioksidan aktiviteleri araştırıldı. Punica granatum L. çekirdek ve kabuğunun metanol ve hekzan ekstrelerinde serbest radikal giderme aktivite, indirgenme gücü analizleri yapıldı. Elde edilen sonuçlar standart antioksidan olarak bilinen askorbik asit ile karşılaştırıldı. Bu çalışmada elde edilen sonuçlara göre antioksidan aktivite Askorbik asit> Punica granatum L. kabuğu> Puni...

    3. Resonant state expansions

      International Nuclear Information System (INIS)

      Lind, P.

      1993-02-01

      The completeness properties of the discrete set of bound state, virtual states and resonances characterizing the system of a single nonrelativistic particle moving in a central cutoff potential is investigated. From a completeness relation in terms of these discrete states and complex scattering states one can derive several Resonant State Expansions (RSE). It is interesting to obtain purely discrete expansion which, if valid, would significantly simplify the treatment of the continuum. Such expansions can be derived using Mittag-Leffler (ML) theory for a cutoff potential and it would be nice to see if one can obtain the same expansions starting from an eigenfunction theory that is not restricted to a finite sphere. The RSE of Greens functions is especially important, e.g. in the continuum RPA (CRPA) method of treating giant resonances in nuclear physics. The convergence of RSE is studied in simple cases using square well wavefunctions in order to achieve high numerical accuracy. Several expansions can be derived from each other by using the theory of analytic functions and one can the see how to obtain a natural discretization of the continuum. Since the resonance wavefunctions are oscillating with an exponentially increasing amplitude, and therefore have to be interpreted through some regularization procedure, every statement made about quantities involving such states is checked by numerical calculations.Realistic nuclear wavefunctions, generated by a Wood-Saxon potential, are used to test also the usefulness of RSE in a realistic nuclear calculation. There are some fundamental differences between different symmetries of the integral contour that defines the continuum in RSE. One kind of symmetry is necessary to have an expansion of the unity operator that is idempotent. Another symmetry must be used if we want purely discrete expansions. These are found to be of the same form as given by ML. (29 refs.)

    4. Controlling thermal deformation by using composite materials having variable fiber volume fraction

      International Nuclear Information System (INIS)

      Bouremana, M.; Tounsi, A.; Kaci, A.; Mechab, I.

      2009-01-01

      In application, many thin structural components such as beams, plates and shells experience a through-thickness temperature variation. This temperature variation can produce both an in-plane expansion and an out-of-plane (bending) curvature. Given that these thin components interact with or connect to other components, we often wish to minimize the thermal deformation or match the thermal deformation of another component. This is accomplished by using a composite whose fibers have a negative axial thermal expansion coefficient. By varying the fiber volume fraction within a symmetric laminated beam to create a functionally graded material (FGM), certain thermal deformations can be controlled or tailored. Specifically, a beam can be designed which does not curve under a steady-state through-thickness temperature variation. Continuous gradation of the fiber volume fraction in the FGM layer is modelled in the form of a mth power polynomial of the coordinate axis in thickness direction of the beam. The beam results are independent of the actual temperature values, within the limitations of steady-state heat transfer and constant material properties. The influence of volume fiber fraction distributions are studied to match or eliminate an in-plane expansion coefficient, or to match a desired axial stiffness. Combining two fiber types to create a hybrid FGM can offer desirable increase in axial and bending stiffness while still retaining the useful thermal deformation behavior.

    5. Kanser hastalarında kemoterapinin C-reaktif protein düzeyine ve yaşam kalitesine olan etkileri

      OpenAIRE

      Gürler, Mehmet Yavuz

      2011-01-01

      Giriş ve Amaç: Bir inflamasyon belirteci ve akut faz reaktanı olan C-reaktif protein, karaciğer ve yağ dokusunda üretilen bir beta globulindir. Günümüz pratiğinde pek çok hastalığın tanısını desteklerken bazı hastalıkların ise takibinde ve alevlenmesinde güvenilir bir belirteçtir. Son yıllarda yapılan çalışmalar göstermiş ki kanser hastalarında bakılan serum CRP düzeyi hastalığın yaygınlığı, hastanın yaşam kalitesi, prognozu ve kemoterapiye yanıtı değerlendirmede kullanılabilme...

    6. Anisotropic expansion of Pu through the α-β-γ phase transitions while under radial compressive stress

      Science.gov (United States)

      Spearing, Dane R.; Veirs, D. Kirk; Prenger, F. Coyne

      2000-07-01

      In support of the new US Department of Energy (DOE) standard for the stabilization, packaging, and storage of plutonium bearing materials, the effects of the volume expansion associated with the α/β and β/γ transformations of Pu metal on the integrity of a stainless steel storage container were examined.

    7. Confined Water in Layered Silicates: The Origin of Anomalous Thermal Expansion Behavior in Calcium-Silicate-Hydrates

      International Nuclear Information System (INIS)

      Krishnan, N. M. Anoop; Wang, Bu; Falzone, Gabriel; Le Pape, Yann; Neithalath, Narayanan

      2016-01-01

      Water, under conditions of nanoscale confinement, exhibits anomalous dynamics, and enhanced thermal deformations, which may be further enhanced when such water is in contact with hydrophilic surfaces. Such heightened thermal deformations of water could control the volume stability of hydrated materials containing nanoconfined structural water. Understanding and predicting the thermal deformation coefficient (TDC, often referred to as the CTE, coefficient of thermal expansion), which represents volume changes induced in materials under conditions of changing temperature, is of critical importance for hydrated solids including: hydrogels, biological tissues, and calcium silicate hydrates, as changes in their volume can result in stress development, and cracking. By pioneering atomistic simulations, we examine the physical origin of thermal expansion in calcium-silicate-hydrates (C–S–H), the binding agent in concrete that is formed by the reaction of cement with water. We report that the TDC of C–S–H shows a sudden increase when the CaO/SiO_2 (molar ratio; abbreviated as Ca/Si) exceeds 1.5. This anomalous behavior arises from a notable increase in the confinement of water contained in the C–S–H’s nanostructure. We identify that confinement is dictated by the topology of the C–S–H’s atomic network. Altogether, the results suggest that thermal deformations of hydrated silicates can be altered by inducing compositional changes, which in turn alter the atomic topology and the resultant volume stability of the solids.

    8. Confined Water in Layered Silicates: The Origin of Anomalous Thermal Expansion Behavior in Calcium-Silicate-Hydrates.

      Science.gov (United States)

      Krishnan, N M Anoop; Wang, Bu; Falzone, Gabriel; Le Pape, Yann; Neithalath, Narayanan; Pilon, Laurent; Bauchy, Mathieu; Sant, Gaurav

      2016-12-28

      Water, under conditions of nanoscale confinement, exhibits anomalous dynamics, and enhanced thermal deformations, which may be further enhanced when such water is in contact with hydrophilic surfaces. Such heightened thermal deformations of water could control the volume stability of hydrated materials containing nanoconfined structural water. Understanding and predicting the thermal deformation coefficient (TDC, often referred to as the CTE, coefficient of thermal expansion), which represents volume changes induced in materials under conditions of changing temperature, is of critical importance for hydrated solids including: hydrogels, biological tissues, and calcium silicate hydrates, as changes in their volume can result in stress development, and cracking. By pioneering atomistic simulations, we examine the physical origin of thermal expansion in calcium-silicate-hydrates (C-S-H), the binding agent in concrete that is formed by the reaction of cement with water. We report that the TDC of C-S-H shows a sudden increase when the CaO/SiO 2 (molar ratio; abbreviated as Ca/Si) exceeds 1.5. This anomalous behavior arises from a notable increase in the confinement of water contained in the C-S-H's nanostructure. We identify that confinement is dictated by the topology of the C-S-H's atomic network. Taken together, the results suggest that thermal deformations of hydrated silicates can be altered by inducing compositional changes, which in turn alter the atomic topology and the resultant volume stability of the solids.

    9. VARLIK VERGİSİ VE MERSİN UYGULAMASI

      OpenAIRE

      ÇANAK, Erdem

      2016-01-01

      Türkiye, İkinci Dünya Savaşı’na girmemekle birlikte savaşın bütün sıkıntılarını yaşamıştır. Hatta bu sırada 1 milyona yakın vatandaşını da silâhaltına almıştır. Ülkenin çalışan ve üretim yapan nüfusunun silâhaltına alınması ise üretimde ciddi düşüşlere sebebiyet vermiştir. Bunun yanı sıra savaşın neden olduğu iktisadi sıkıntıların etkisiyle enflasyon yükselmiş, karaborsa ve vurgunculuk artmıştır. Bu durumdan en çok istifade edenler ise büyük toprak sahibi çiftçiler ile ticaretle iştigal eden ...

    10. Numerical investigation of over expanded flow behavior in a single expansion ramp nozzle

      Science.gov (United States)

      Mousavi, Seyed Mahmood; Pourabidi, Reza; Goshtasbi-Rad, Ebrahim

      2018-05-01

      The single expansion ramp nozzle is severely over-expanded when the vehicle is at low speed, which hinders its ability to provide optimal configurations for combined cycle engines. The over-expansion leads to flow separation as a result of shock wave/boundary-layer interaction. Flow separation, and the presence of shocks themselves, result in a performance loss in the single expansion ramp nozzle, leading to reduced thrust and increased pressure losses. In the present work, the unsteady two dimensional compressible flow in an over expanded single expansion ramp nozzle has been investigated using finite volume code. To achieve this purpose, the Reynolds stress turbulence model and full multigrid initialization, in addition to the Smirnov's method for examining the errors accumulation, have been employed and the results are compared with available experimental data. The results show that the numerical code is capable of predicting the experimental data with high accuracy. Afterward, the effect of discontinuity jump in wall temperature as well as the length of straight ramp on flow behavior have been studied. It is concluded that variations in wall temperature and length of straight ramp change the shock wave boundary layer interaction, shock structure, shock strength as well as the distance between Lambda shocks.

    11. Accounting for Debye sheath expansion for proud Langmuir probes in magnetic confinement fusion plasmas.

      Science.gov (United States)

      Tsui, C K; Boedo, J A; Stangeby, P C

      2018-01-01

      A Child-Langmuir law-based method for accounting for Debye sheath expansion while fitting the current-voltage I-V characteristic of proud Langmuir probes (electrodes that extend into the volume of the plasma) is described. For Langmuir probes of a typical size used in tokamak plasmas, these new estimates of electron temperature and ion saturation current density values decreased by up to 60% compared to methods that did not account for sheath expansion. Changes to the collection area are modeled using the Child-Langmuir law and effective expansion perimeter l p , and the model is thus referred to as the "perimeter sheath expansion method." l p is determined solely from electrode geometry, so the method may be employed without prior measurement of the magnitude of the sheath expansion effects for a given Langmuir probe and can be used for electrodes of different geometries. This method correctly predicts the non-saturating ΔI/ΔV slope for cold, low-density plasmas where sheath-expansion effects are strong, as well as for hot plasmas where ΔI/ΔV ∼ 0, though it is shown that the sheath can still significantly affect the collection area in these hot conditions. The perimeter sheath expansion method has several advantages compared to methods where the non-saturating current is fitted: (1) It is more resilient to scatter in the I-V characteristics observed in turbulent plasmas. (2) It is able to separate the contributions to the ΔI/ΔV slope from sheath expansion to that of the high energy electron tail in high Te conditions. (3) It calculates the change in the collection area due to the Debye sheath for conditions where ΔI/ΔV ∼ 0 and for V = V f .

    12. One Stage Reconstruction of Skull Exposed by Burn Injury Using a Tissue Expansion Technique

      Directory of Open Access Journals (Sweden)

      Jae Young Cho

      2012-03-01

      Full Text Available BackgroundAn area of the skull exposed by burn injury has been covered by various methods including local flap, skin graft, or free flap surgery. Each method has disadvantages, such as postoperative alopecia or donor site morbidities. Due to the risk of osteomyelitis in the injured skull during the expansion period, tissue expansion was excluded from primary reconstruction. However, successful primary reconstruction was possible in burned skull by tissue expansion.MethodsFrom January 2000 to 2011, tissue expansion surgery was performed on 10 patients who had sustained electrical burn injuries. In the 3 initial cases, removal of the injured part of the skull and a bone graft was performed. In the latter 7 cases, the injured skull tissue was preserved and covered with a scalp flap directly to obtain natural bone healing and bone remodeling.ResultsThe mean age of patients was 49.9±12.2 years, with 8 male and 2 female. The size of the burn wound was an average of 119.6±36.7 cm2. The mean expansion duration was 65.5±5.6 days, and the inflation volume was an average of 615±197.6 mL. Mean defect size was 122.2±34.9 cm2. The complications including infection, hematoma, and the exposure of the expander were observed in 4 cases. Nonetheless, only 1 case required revision.ConclusionsSuccessful coverage was performed by tissue expansion surgery in burned skull primarily and no secondary reconstruction was needed. Although the risks of osteomyelitis during the expansion period were present, constant coverage of the injured skull and active wound treatment helped successful primary reconstruction of burned skull by tissue expansion.

    13. Türkiye’de Yemeklik Tane Baklagiller Üretiminin Sorunları ve Çözüm Önerileri

      Directory of Open Access Journals (Sweden)

      Aybegün Ton

      2014-05-01

      Full Text Available Türkiye’de yemeklik tane baklagiller içerisinde ekim alanı ve üretim bakımından ilk sırayı nohut almakta, bunu sırasıyla mercimek, fasulye ve bakla izlemektedir. Türkiye, özellikle nohut ve mercimekte Dünyada en önemli üretici ve ihracatçı ülkeler içerisinde bulunmaktadır. Son yıllarda ise nohut ve mercimek üretimimiz ve ihracatımız bir azalma eğilimi içerisinde bulunmaktadır. Bununla birlikte, birçok yemeklik tane baklagil türlerinin üretimine uygun farklı ekolojik koşulları içeren bölgelerimiz bulunmaktadır. Bu üretim potansiyelimiz değerlendirilmeli, dış pazarların istekleri doğrultusunda, standart irilikte, kaliteli ve yüksek verim potansiyeline sahip çeşitlerimizin üretimine önem verilmelidir. Ayrıca, uygun yetiştirme teknikleri kullanılarak üretim yapılmalı, kıyı bölgelerimizde kışlık nohut yetiştiriciliği, iç bölgelerimizde kışlık mercimek yetiştiriciliği yaygınlaştırılmalı, ekimde ve hasat da makine kullanımına önem verilmeli, hastalık ve zararlılarla yeterli düzeyde mücadele edilerek verimlilik artırılmalıdır. Böylece, Türkiye’de yemeklik tane baklagiller tarımının bugünkünden çok daha fazla yaygınlaştırılması mümkün görülmektedir.

    14. İnternet ve Tuğla-Harç Mağazalarına İlişkin Müşteri Düşünceleri ve Değişen Müşteri Davranışları

      Directory of Open Access Journals (Sweden)

      Abdolrazagh MADAHI

      2014-09-01

      Full Text Available Bu çalışma Malezya’da internette faaliyet gösteren tuğla harç mağazalarına ilişkin müşteri düşüncelerini ve müşterilerin değişen kanal eğilimlerini analiz etmeyi amaçlamaktadır. Çalışmaya ilişkin veriler Klang Vadisi ve Penang Bölgesi’nde 497 kişinin katılımıyla gerçekleştirilen anketlerin neticesinde elde edilmiştir. Çalışmada yapısal bağlamda PLS Modeli ve data analizi bağlamında ise SEM Modeli kullanılmıştır. Yapılan 497 anketin neticesinde, çalışmanın verileri, uygunluk ve zorluk bağlamında internetten tuğla ve harç mağazalara doğru değişen bir eğilim olduğunu göstermiştir. Bulgular benzer şekilde cinsiyet ve niyetin de müşterilerin kanal değiştirmesinde etkin unsurlar olduğunu ortaya koymuştur.

    15. Pressure Dependence of Molar Volume near the Melting Point in Benzene

      Institute of Scientific and Technical Information of China (English)

      2007-01-01

      The pressure dependence of the molar volume was at constant temperatures close to the melting point in benzene. The molar volume of benzene was calculated using experimental data for the thermal expansivity for constant temperatures of 25℃, 28.5℃, 40℃, and 51℃ at various pressures for both the solid and liquid phases. The predictions are in good agreement with the observed volumes in both the solid and liquid phases of benzene. The predicted values of the molar volume for a constant temperature of 28.5℃ in the liquid phase of benzene agree well with experimental data in the literature.

    16. Brain expansion in patients with type II diabetes following insulin therapy: a preliminary study with longitudinal voxel-based morphometry.

      Science.gov (United States)

      Chen, Zhiye; Li, Jinfeng; Sun, Jie; Ma, Lin

      2014-01-01

      We performed a longitudinal analysis based on magnetic resonance (MR) imaging to investigate the brain structural and perfusion changes caused by insulin therapy in patients with type II diabetes. High resolution three-dimensional T1-weighted fast spoiled gradient recalled echo images and flow-sensitive alternating inversion recovery (FAIR) images were obtained from 11 patients with type II diabetes before and 1 year after initiation of insulin therapy and 11 normal controls. Brain volume changes were investigated by a longitudinal voxel-based morphometry (VBM), and perfusion changes were evaluated by FAIR imaging between baseline and follow-up data. Significant regional gray matter (GM) expansion located in bilateral frontal, parietal, and left occipital lobes, and regional white matter (WM) expansion was shown in left precentral subcortical WM and right angular subcortical WM after insulin therapy (P Brain hyperperfusion was detected in bilateral frontal cortex, left occipital cortex, and right temporal cortex after insulin therapy (P brain expansion and hyperperfusion were demonstrated 1 year after initiation of insulin therapy, and insulin therapy could contribute to the brain volume gainment in the patients with type II diabetes. Copyright © 2013 by the American Society of Neuroimaging.

    17. Volume-activated trimethylamine oxide efflux in red blood cells of spiny dogfish (Squalus acanthias).

      Science.gov (United States)

      Koomoa, D L; Musch, M W; MacLean, A V; Goldstein, L

      2001-09-01

      The aims of this study were to determine the pathway of swelling-activated trimethylamine oxide (TMAO) efflux and its regulation in spiny dogfish (Squalus acanthias) red blood cells and compare the characteristics of this efflux pathway with the volume-activated osmolyte (taurine) channel present in erythrocytes of fishes. The characteristics of the TMAO efflux pathway were similar to those of the taurine efflux pathway. The swelling-activated effluxes of both TMAO and taurine were significantly inhibited by known anion transport inhibitors (DIDS and niflumic acid) and by the general channel inhibitor quinine. Volume expansion by hypotonicity, ethylene glycol, and diethyl urea activated both TMAO and taurine effluxes similarly. Volume expansion by hypotonicity, ethylene glycol, and diethyl urea also stimulated the activity of tyrosine kinases p72syk and p56lyn, although the stimulations by the latter two treatments were less than by hypotonicity. The volume activations of both TMAO and taurine effluxes were inhibited by tyrosine kinase inhibitors, suggesting that activation of tyrosine kinases may play a role in activating the osmolyte effluxes. These results indicate that the volume-activated TMAO efflux occurs via the organic osmolyte (taurine) channel and may be regulated by the volume activation of tyrosine kinases.

    18. Bilimsel iletişimde yeşil ve altın yollarda yakınsama ve Türkiye'deki yansımaları = Convergence of the gold and green roads at scholarly communication and reflections on Turkey

      Directory of Open Access Journals (Sweden)

      Şengül, Gökhan

      2011-01-01

      Full Text Available Son yıllarda özellikle sosyal ağlarda bilgi dolaşımının artması, gelişmiş mobil iletişim cihazlarının yoğun kullanımı kısıtsız ve farklı ortamlarda bilgi erişim ve paylaşımını gerektirmektedir. Bu bağlamda bilimsel bulguların yer aldığı makalelerin geniş kitlelere ve diğer bilim insanlarının erişimine açılması; hem bilimsel eserin doğruluk ve güvenirliğini artırmaya yardımcı olmakta, hem de bilimsel verinin paylaşılmasını ve dolayısı ile de bilimsel gelişimi olumlu yönde etkilemektedir. Yaklaşık on yıldır bu amaca açık erişim insiyatifi katkı sağlamaktadır. Bu amaçla kendi kendine arşivleme (yeşil yol ve açık erişim dergisi (altın yol bilimsel çalışmaların bilim topluluğuna sunulmasında yeni yöntemler olarak takdim edilmiştir Bu çalışmada; uluslararası alanda yeşil ve altın yollar üzerinde ortaya konan kurallar irdelenmiş, yazar ve yayıncılarının oluşan iklime uyumluluğu sorgulanmış ve Türkiye adresli kurumsal arşiv ve dergilerin ortaya çıkan durum karşısında konumları üzerine bir değerlendirme yapılmıştır. Çalışma esnasında Ulrich Süreli Yayın Rehberi, Thomson Reuters (ISI Bilimsel Web (Web of Science - WoS ve Elsevier Scopus uluslararası ticari atıf veri tabanları, RoMEO, Juliet, ve ROARMAP telif politikası rehberleri, OpenDOAR, ROAR kurumsal arşiv rehberleri ve DOAJ açık erişim dergisi rehberi ile ULAKBİM ulusal veri tabanları incelenmiştir. / In parallel with the increase of information exchange rate in social networks and the usage of mobile communication devices in recent years, it is also required that the information needs to be shared and freely accessable in different enviroments. In this context freely access to the papers including scientific findings by other scientists and broad population will help to increase both the accuracy and reability of the papers. Besides it will also affect positively the

    19. Motion-specific internal target volumes for FDG-avid mediastinal and hilar lymph nodes

      International Nuclear Information System (INIS)

      Lamb, James M.; Robinson, Clifford G.; Bradley, Jeffrey D.; Low, Daniel A.

      2013-01-01

      Background and purpose: To quantify the benefit of motion-specific internal target volumes for FDG-avid mediastinal and hilar lymph nodes generated using 4D-PET, vs. conventional internal target volumes generated using non-respiratory gated PET and 4D-CT scans. Materials and methods: Five patients with FDG-avid tumors metastatic to 11 hilar or mediastinal lymph nodes were imaged with respiratory-correlated FDG-PET (4D-PET) and 4D-CT. FDG-avid nodes were contoured by a radiation oncologist in two ways. Standard-of-care volumes were contoured using conventional un-gated PET, 4D-CT, and breath-hold CT. A second, motion-specific, set of volumes were contoured using 4D-PET.Contours based on 4D-PET corresponded directly to an internal target volume (ITV 4D ), whereas contours based on un-gated PET were expanded by a series of exploratory isotropic margins (from 5 to 13 mm) based on literature recommendations on lymph node motion to form internal target volumes (ITV 3D ). Results: A 13 mm expansion of the un-gated PET nodal volume was needed to cover the ITV 4D for 10 of 11 nodes studied. The ITV 3D based on a 13 mm expansion included on average 45 cm 3 of tissue that was not included in the ITV 4D . Conclusions: Motion-specific lymph-node internal target volumes generated from 4D-PET imaging could be used to improve accuracy and/or reduce normal-tissue irradiation compared to the standard-of-care un-gated PET based internal target volumes

    20. Isotropic Negative Thermal Expansion Metamaterials.

      Science.gov (United States)

      Wu, Lingling; Li, Bo; Zhou, Ji

      2016-07-13

      Negative thermal expansion materials are important and desirable in science and engineering applications. However, natural materials with isotropic negative thermal expansion are rare and usually unsatisfied in performance. Here, we propose a novel method to achieve two- and three-dimensional negative thermal expansion metamaterials via antichiral structures. The two-dimensional metamaterial is constructed with unit cells that combine bimaterial strips and antichiral structures, while the three-dimensional metamaterial is fabricated by a multimaterial 3D printing process. Both experimental and simulation results display isotropic negative thermal expansion property of the samples. The effective coefficient of negative thermal expansion of the proposed models is demonstrated to be dependent on the difference between the thermal expansion coefficient of the component materials, as well as on the circular node radius and the ligament length in the antichiral structures. The measured value of the linear negative thermal expansion coefficient of the three-dimensional sample is among the largest achieved in experiments to date. Our findings provide an easy and practical approach to obtaining materials with tunable negative thermal expansion on any scale.