Minimum Additive Waste Stabilization (MAWS)

International Nuclear Information System (INIS)

1994-02-01

In the Minimum Additive Waste Stabilization(MAWS) concept, actual waste streams are utilized as additive resources for vitrification, which may contain the basic components (glass formers and fluxes) for making a suitable glass or glassy slag. If too much glass former is present, then the melt viscosity or temperature will be too high for processing; while if there is too much flux, then the durability may suffer. Therefore, there are optimum combinations of these two important classes of constituents depending on the criteria required. The challenge is to combine these resources in such a way that minimizes the use of non-waste additives yet yields a processable and durable final waste form for disposal. The benefit to this approach is that the volume of the final waste form is minimized (waste loading maximized) since little or no additives are used and vitrification itself results in volume reduction through evaporation of water, combustion of organics, and compaction of the solids into a non-porous glass. This implies a significant reduction in disposal costs due to volume reduction alone, and minimizes future risks/costs due to the long term durability and leach resistance of glass. This is accomplished by using integrated systems that are both cost-effective and produce an environmentally sound waste form for disposal. individual component technologies may include: vitrification; thermal destruction; soil washing; gas scrubbing/filtration; and, ion-exchange wastewater treatment. The particular combination of technologies will depend on the waste streams to be treated. At the heart of MAWS is vitrification technology, which incorporates all primary and secondary waste streams into a final, long-term, stabilized glass wasteform. The integrated technology approach, and view of waste streams as resources, is innovative yet practical to cost effectively treat a broad range of DOE mixed and low-level wastes

A New Approach for Deep Gray Matter Analysis Using Partial-Volume Estimation.

Science.gov (United States)

Bonnier, Guillaume; Kober, Tobias; Schluep, Myriam; Du Pasquier, Renaud; Krueger, Gunnar; Meuli, Reto; Granziera, Cristina; Roche, Alexis

2016-01-01

The existence of partial volume effects in brain MR images makes it challenging to understand physio-pathological alterations underlying signal changes due to pathology across groups of healthy subjects and patients. In this study, we implement a new approach to disentangle gray and white matter alterations in the thalamus and the basal ganglia. The proposed method was applied to a cohort of early multiple sclerosis (MS) patients and healthy subjects to evaluate tissue-specific alterations related to diffuse inflammatory or neurodegenerative processes. Forty-three relapsing-remitting MS patients and nineteen healthy controls underwent 3T MRI including: (i) fluid-attenuated inversion recovery, double inversion recovery, magnetization-prepared gradient echo for lesion count, and (ii) T1 relaxometry. We applied a partial volume estimation algorithm to T1 relaxometry maps to gray and white matter local concentrations as well as T1 values characteristic of gray and white matter in the thalamus and the basal ganglia. Statistical tests were performed to compare groups in terms of both global T1 values, tissue characteristic T1 values, and tissue concentrations. Significant increases in global T1 values were observed in the thalamus (p = 0.038) and the putamen (p = 0.026) in RRMS patients compared to HC. In the Thalamus, the T1 increase was associated with a significant increase in gray matter characteristic T1 (p = 0.0016) with no significant effect in white matter. The presented methodology provides additional information to standard MR signal averaging approaches that holds promise to identify the presence and nature of diffuse pathology in neuro-inflammatory and neurodegenerative diseases.

Evaluation of two intracavitary high-dose-rate brachytherapy devices for irradiating additional and irregularly shaped volumes of breast tissue

International Nuclear Information System (INIS)

Lu, Sharon M.; Scanderbeg, Daniel J.; Barna, Patrick; Yashar, William; Yashar, Catheryn

2012-01-01

The SAVI and Contura breast brachytherapy applicators represent 2 recent advancements in brachytherapy technology that have expanded the number of women eligible for accelerated partial breast irradiation in the treatment of early-stage breast cancer. Early clinical experience with these 2 single-entry, multichannel high-dose-rate brachytherapy devices confirms their ease of use and dosimetric versatility. However, current clinical guidelines for SAVI and Contura brachytherapy may result in a smaller or less optimal volume of treated tissue compared with traditional interstitial brachytherapy. This study evaluates the feasibility of using the SAVI and Contura to irradiate larger and irregularly shaped target volumes, approaching what is treatable with the interstitial technique. To investigate whether additional tissue can be treated, 17 patients treated with the SAVI and 3 with the Contura were selected. For each patient, the planning target volume (PTV) was modified to extend 1.1 cm, 1.3 cm, and 1.5 cm beyond the tumor bed cavity. To evaluate dose conformance to an irregularly shaped target volume, 9 patients treated with the SAVI and 3 with the Contura were selected from the original 20 patients. The following asymmetric PTV margin combinations were assessed for each patient: 1.5/0.3, 1.3/0.3, and 1.1/0.3 cm. For all patients, treatment planning was performed, adopting the National Surgical Adjuvant Breast and Bowel Project guidelines, and dosimetric comparisons were made. The 6–1 and 8–1 SAVI devices can theoretically treat a maximal tissue margin of 1.5 cm and an asymmetric PTV with margins ranging from 0.3 to 1.5 cm. The 10–1 SAVI and Contura can treat a maximal margin of 1.3 cm and 1.1 cm, respectively, and asymmetric PTV with margins ranging from 0.3–1.3 cm. Compared with the Contura, the SAVI demonstrated greater dosimetric flexibility. Risk of developing excessive hot spots increased with the size of the SAVI device. Both the SAVI and Contura

Ion Recognition Approach to Volume Reduction of Alkaline Tank Waste by Separation and Recycle of Sodium Hydroxide and Sodium Nitrate

International Nuclear Information System (INIS)

Moyer, Bruce A.; Marchand, Alan P.; Bonnesen, Peter V.; Bryan, Jeffrey C.; Haverlock, Tamara J.

2004-01-01

This research was intended to provide the scientific foundation upon which the feasibility of liquid-liquid extraction chemistry for bulk reduction of the volume of high-activity tank waste can be evaluated. Primary focus has been on sodium hydroxide separation, with potential Hanford application. Value in sodium hydroxide separation can potentially be found in alternative flowsheets for treatment and disposal of low-activity salt waste. Additional value can be expected in recycle of sodium hydroxide for use in waste retrieval and sludge washing, whereupon additions of fresh sodium hydroxide to the waste can be avoided. Potential savings are large both because of the huge cost of vitrification of the low-activity waste stream and because volume reduction of high-activity wastes could obviate construction of costly new tanks. Toward these ends, the conceptual development begun in the original proposal was extended with the formulation of eight fundamental approaches that could be undertaken for extraction of sodium hydroxide

Brain tissues volume measurements from 2D MRI using parametric approach

Science.gov (United States)

L'vov, A. A.; Toropova, O. A.; Litovka, Yu. V.

2018-04-01

The purpose of the paper is to propose a fully automated method of volume assessment of structures within human brain. Our statistical approach uses maximum interdependency principle for decision making process of measurements consistency and unequal observations. Detecting outliers performed using maximum normalized residual test. We propose a statistical model which utilizes knowledge of tissues distribution in human brain and applies partial data restoration for precision improvement. The approach proposes completed computationally efficient and independent from segmentation algorithm used in the application.

Effects of a Multidisciplinary Approach to Improve Volume of Diagnostic Material in CT-Guided Lung Biopsies.

Science.gov (United States)

Ferguson, Philip E; Sales, Catherine M; Hodges, Dalton C; Sales, Elizabeth W

2015-01-01

Recent publications have emphasized the importance of a multidisciplinary strategy for maximum conservation and utilization of lung biopsy material for advanced testing, which may determine therapy. This paper quantifies the effect of a multidisciplinary strategy implemented to optimize and increase tissue volume in CT-guided transthoracic needle core lung biopsies. The strategy was three-pronged: (1) once there was confidence diagnostic tissue had been obtained and if safe for the patient, additional biopsy passes were performed to further increase volume of biopsy material, (2) biopsy material was placed in multiple cassettes for processing, and (3) all tissue ribbons were conserved when cutting blocks in the histology laboratory. This study quantifies the effects of strategies #1 and #2. This retrospective analysis comparing CT-guided lung biopsies from 2007 and 2012 (before and after multidisciplinary approach implementation) was performed at a single institution. Patient medical records were reviewed and main variables analyzed include biopsy sample size, radiologist, number of blocks submitted, diagnosis, and complications. The biopsy sample size measured was considered to be directly proportional to tissue volume in the block. Biopsy sample size increased 2.5 fold with the average total biopsy sample size increasing from 1.0 cm (0.9-1.1 cm) in 2007 to 2.5 cm (2.3-2.8 cm) in 2012 (Pstrategy to CT-guided lung biopsies was effective in significantly increasing tissue volume and number of blocks available for advanced diagnostic testing.

A logical approach to determine a waste segregation/volume reduction program

International Nuclear Information System (INIS)

Shriner, G.D.; Carmel, P.G.; Shimmura, H.

1986-01-01

This paper discusses advantages and disadvantages of hand sorting versus use of automated radioactive waste segregation monitors and makes an analysis of costs/versus benefits based on volume with time. Many programs to be employed to prevent unnecessary waste generation with little or no additional cost to the power plant. Parameters needed to perform a cost analysis and methods used to obtain them are discussed. Recommendations on use of vendor-supplied services for segregation, volume reduction, and decontamination are given. The data provided will enable the selection of a program(s) to benefit the individual user's requirements

Estimation of gas and tissue lung volumes by MRI: functional approach of lung imaging.

Science.gov (United States)

Qanadli, S D; Orvoen-Frija, E; Lacombe, P; Di Paola, R; Bittoun, J; Frija, G

1999-01-01

The purpose of this work was to assess the accuracy of MRI for the determination of lung gas and tissue volumes. Fifteen healthy subjects underwent MRI of the thorax and pulmonary function tests [vital capacity (VC) and total lung capacity (TLC)] in the supine position. MR examinations were performed at inspiration and expiration. Lung volumes were measured by a previously validated technique on phantoms. Both individual and total lung volumes and capacities were calculated. MRI total vital capacity (VC(MRI)) was compared with spirometric vital capacity (VC(SP)). Capacities were correlated to lung volumes. Tissue volume (V(T)) was estimated as the difference between the total lung volume at full inspiration and the TLC. No significant difference was seen between VC(MRI) and VC(SP). Individual capacities were well correlated (r = 0.9) to static volume at full inspiration. The V(T) was estimated to be 836+/-393 ml. This preliminary study demonstrates that MRI can accurately estimate lung gas and tissue volumes. The proposed approach appears well suited for functional imaging of the lung.

SLIM-MAUD: an approach to assessing human error probabilities using structured expert judgment. Volume II. Detailed analysis of the technical issues

International Nuclear Information System (INIS)

Embrey, D.E.; Humphreys, P.; Rosa, E.A.; Kirwan, B.; Rea, K.

1984-07-01

This two-volume report presents the procedures and analyses performed in developing an approach for structuring expert judgments to estimate human error probabilities. Volume I presents an overview of work performed in developing the approach: SLIM-MAUD (Success Likelihood Index Methodology, implemented through the use of an interactive computer program called MAUD-Multi-Attribute Utility Decomposition). Volume II provides a more detailed analysis of the technical issues underlying the approach

Influence of high volumes of ultra-fine additions on self-compacting concrete[ACI SP-239

Energy Technology Data Exchange (ETDEWEB)

Cioffi, R. [Naples Univ., Naples (Italy). Faculty of Engineering; Colangelo, F. [Naples Univ., Naples (Italy). Dept. of Technologies; Caputo, D.; Liguori, B. [Naples Univ., Naples (Italy). Dept. of Materials and Production Engineering

2006-07-01

The addition of fine minerals can reduce water demand and increase the slump characteristics of concrete. This paper examined the influence of high volumes of ultra-fine fly ash, raw fly ash, silica fume and natural zeolites on the properties of self-compacting concrete (SCC). Three samples of SCC were prepared using various mineral additions to determine normal slump and J-ring slump flows of fresh concrete as well as the compressive strength and elastic modulus properties of hardened concrete. Cement and crushed limestone natural aggregates were used. The fly ash, silica fume and natural zeolites were subjected to wet high energy milling. The rotating speed, milling time, water-to-solid ratio, and size of milling media were optimized to obtain powders with varying qualities. Results of the study showed that values for the normal slump flow ranged between 604 and 785 mm, while the differences with the J-ring slump flow were less than 30 mm. The samples were then tested to evaluate the mechanical properties of the hardened concrete after 7 and 28 curing days. The modulus of elasticity and compressive strength showed improvements in the concretes containing the ultra-fine fly ash. No segregation phenomena were observed in the case of the cylindrical column specimens. It was concluded that all the specimens provided environmentally sustainable, high workability concretes which can be successfully prepared with the addition of high volumes of minerals. 17 refs., 5 tabs., 6 figs.

A local contrast based approach to threshold segmentation for PET target volume delineation

International Nuclear Information System (INIS)

Drever, Laura; Robinson, Don M.; McEwan, Alexander; Roa, Wilson

2006-01-01

Current radiation therapy techniques, such as intensity modulated radiation therapy and three-dimensional conformal radiotherapy rely on the precise delivery of high doses of radiation to well-defined volumes. CT, the imaging modality that is most commonly used to determine treatment volumes cannot, however, easily distinguish between cancerous and normal tissue. The ability of positron emission tomography (PET) to more readily differentiate between malignant and healthy tissues has generated great interest in using PET images to delineate target volumes for radiation treatment planning. At present the accurate geometric delineation of tumor volumes is a subject open to considerable interpretation. The possibility of using a local contrast based approach to threshold segmentation to accurately delineate PET target cross sections is investigated using well-defined cylindrical and spherical volumes. Contrast levels which yield correct volumetric quantification are found to be a function of the activity concentration ratio between target and background, target size, and slice location. Possibilities for clinical implementation are explored along with the limits posed by this form of segmentation

Matrix approach to consistency of the additive efficient normalization of semivalues

NARCIS (Netherlands)

Xu, G.; Driessen, Theo; Sun, H.; Sun, H.

2007-01-01

In fact the Shapley value is the unique efficient semivalue. This motivated Ruiz et al. to do additive efficient normalization for semivalues. In this paper, by matrix approach we derive the relationship between the additive efficient normalization of semivalues and the Shapley value. Based on the

A risk management approach to double-shell tank waste volume versus storage capacity

Energy Technology Data Exchange (ETDEWEB)

Coles, G.A. [Westinghouse Hanford Co., Richland, WA (United States); Thurkow, T.J.; Fritz, R.L.; Nuhlestein, L.O.; Allen, M.R.; Stuart, R.J. [ARES Corp. (United States)

1996-01-01

A risk-based assessment of the overall waste volume versus double-shell tank storage capacity was conducted to develop fallback positions for projections where the waste volume was at a high risk of exceeding capacity. This study was initiated to provide that assessment. A working simulation model was the primary deliverable of this study. The model validates the approach and demonstrates that simulation analysis can provide a method of tracking uncertainties in available data, assessing probabilities, and serves as a tool to be used by management to determine the consequences of various off-normal occurrences.

A risk management approach to double-shell tank waste volume versus storage capacity

International Nuclear Information System (INIS)

Coles, G.A.; Thurkow, T.J.; Fritz, R.L.; Nuhlestein, L.O.; Allen, M.R.; Stuart, R.J.

1996-01-01

A risk-based assessment of the overall waste volume versus double-shell tank storage capacity was conducted to develop fallback positions for projections where the waste volume was at a high risk of exceeding capacity. This study was initiated to provide that assessment. A working simulation model was the primary deliverable of this study. The model validates the approach and demonstrates that simulation analysis can provide a method of tracking uncertainties in available data, assessing probabilities, and serves as a tool to be used by management to determine the consequences of various off-normal occurrences

Laser-Based Additive Manufacturing of Zirconium

Directory of Open Access Journals (Sweden)

Himanshu Sahasrabudhe

2018-03-01

Full Text Available Additive manufacturing of zirconium is attempted using commercial Laser Engineered Net Shaping (LENSTM technique. A LENSTM-based approach towards processing coatings and bulk parts of zirconium, a reactive metal, aims to minimize the inconvenience of traditional metallurgical practices of handling and processing zirconium-based parts that are particularly suited to small volumes and one-of-a-kind parts. This is a single-step manufacturing approach for obtaining near net shape fabrication of components. In the current research, Zr metal powder was processed in the form of coating on Ti6Al4V alloy substrate. Scanning electron microscopy (SEM and energy dispersive spectroscopy (EDS as well as phase analysis via X-ray diffraction (XRD were studied on these coatings. In addition to coatings, bulk parts were also fabricated using LENS™ from Zr metal powders, and measured part accuracy.

Beneficiation-hydroretort processing of US oil shales: Volume 2

Energy Technology Data Exchange (ETDEWEB)

None

1989-01-01

This report has been divided into three volumes. Volume I describes the MRI beneficiation work. In addition, Volume I presents the results of joint beneficiation-hydroretorting studies and provides an economic analysis of the combined beneficiation-hydroretorting approach for processing Eastern oil shales. Volume II presents detailed results of hydroretorting tests made by HYCRUDE/IGT on raw and beneficiated oil shales prepared by MRI. Volume III comprises detailed engineering design drawings and supporting data developed by the Roberts and Schaefer Company, Engineers and Contractors, Salt Lake City, Utah, in support of the capital and operating costs for a conceptual beneficiation plant processing an Alabama oil shale.

Additive Manufacturing for Low Volume Bearings

Energy Technology Data Exchange (ETDEWEB)

Tate, John G. [Schaeffler Group USA, Spartanburg, SC (United States); Richardson, Bradley S. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Love, Lonnie J. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)

2017-09-01

ORNL worked with the Schaeffler Group USA to explore additive manufacturing techniques that might be appropriate for prototyping of bearing cages. Multiple additive manufacturing techniques were investigated, including e-beam, binder jet and multiple laser based processes. The binder jet process worked best for the thin, detailed cages printed.

"Combining equity and utilitarianism"-additional insights into a novel approach

NARCIS (Netherlands)

Lemmen-Gerdessen, van Joke; Kanellopoulos, Argyris; Claassen, Frits

2018-01-01

Recently, a novel approach (to be referred to as CEU) was introduced for the frequently arising problem of combining the conflicting criteria of equity and utilitarianism. This paper provides additional insights into CEU and assesses its added value for practice by comparing it with a commonly used

Patterns of failure after the reduced volume approach for elective nodal irradiation in nasopharyngeal carcinoma.

Science.gov (United States)

Seol, Ki Ho; Lee, Jeong Eun

2016-03-01

To evaluate the patterns of nodal failure after radiotherapy (RT) with the reduced volume approach for elective neck nodal irradiation (ENI) in nasopharyngeal carcinoma (NPC). Fifty-six NPC patients who underwent definitive chemoradiotherapy with the reduced volume approach for ENI were reviewed. The ENI included retropharyngeal and level II lymph nodes, and only encompassed the echelon inferior to the involved level to eliminate the entire neck irradiation. Patients received either moderate hypofractionated intensity-modulated RT for a total of 72.6 Gy (49.5 Gy to elective nodal areas) or a conventional fractionated three-dimensional conformal RT for a total of 68.4-72 Gy (39.6-45 Gy to elective nodal areas). Patterns of failure, locoregional control, and survival were analyzed. The median follow-up was 38 months (range, 3 to 80 months). The out-of-field nodal failure when omitting ENI was none. Three patients developed neck recurrences (one in-field recurrence in the 72.6 Gy irradiated nodal area and two in the elective irradiated region of 39.6 Gy). Overall disease failure at any site developed in 11 patients (19.6%). Among these, there were six local failures (10.7%), three regional failures (5.4%), and five distant metastases (8.9%). The 3-year locoregional control rate was 87.1%, and the distant failure-free rate was 90.4%; disease-free survival and overall survival at 3 years was 80% and 86.8%, respectively. No patient developed nodal failure in the omitted ENI site. Our investigation has demonstrated that the reduced volume approach for ENI appears to be a safe treatment approach in NPC.

Patterns of failure after the reduced volume approach for elective nodal irradiation in nasopharyngeal carcinoma

Energy Technology Data Exchange (ETDEWEB)

Seol, Ki Ho; Lee, Jeong Eun [Dept. of Radiation Oncology, Kyungpook National University School of Medicine, Daegu (Korea, Republic of)

2016-03-15

To evaluate the patterns of nodal failure after radiotherapy (RT) with the reduced volume approach for elective neck nodal irradiation (ENI) in nasopharyngeal carcinoma (NPC). Fifty-six NPC patients who underwent definitive chemoradiotherapy with the reduced volume approach for ENI were reviewed. The ENI included retropharyngeal and level II lymph nodes, and only encompassed the echelon inferior to the involved level to eliminate the entire neck irradiation. Patients received either moderate hypofractionated intensity-modulated RT for a total of 72.6 Gy (49.5 Gy to elective nodal areas) or a conventional fractionated three-dimensional conformal RT for a total of 68.4-72 Gy (39.6-45 Gy to elective nodal areas). Patterns of failure, locoregional control, and survival were analyzed. The median follow-up was 38 months (range, 3 to 80 months). The out-of-field nodal failure when omitting ENI was none. Three patients developed neck recurrences (one in-field recurrence in the 72.6 Gy irradiated nodal area and two in the elective irradiated region of 39.6 Gy). Overall disease failure at any site developed in 11 patients (19.6%). Among these, there were six local failures (10.7%), three regional failures (5.4%), and five distant metastases (8.9%). The 3-year locoregional control rate was 87.1%, and the distant failure-free rate was 90.4%; disease-free survival and overall survival at 3 years was 80% and 86.8%, respectively. No patient developed nodal failure in the omitted ENI site. Our investigation has demonstrated that the reduced volume approach for ENI appears to be a safe treatment approach in NPC.

Patterns of failure after the reduced volume approach for elective nodal irradiation in nasopharyngeal carcinoma

International Nuclear Information System (INIS)

Seol, Ki Ho; Lee, Jeong Eun

2016-01-01

To evaluate the patterns of nodal failure after radiotherapy (RT) with the reduced volume approach for elective neck nodal irradiation (ENI) in nasopharyngeal carcinoma (NPC). Fifty-six NPC patients who underwent definitive chemoradiotherapy with the reduced volume approach for ENI were reviewed. The ENI included retropharyngeal and level II lymph nodes, and only encompassed the echelon inferior to the involved level to eliminate the entire neck irradiation. Patients received either moderate hypofractionated intensity-modulated RT for a total of 72.6 Gy (49.5 Gy to elective nodal areas) or a conventional fractionated three-dimensional conformal RT for a total of 68.4-72 Gy (39.6-45 Gy to elective nodal areas). Patterns of failure, locoregional control, and survival were analyzed. The median follow-up was 38 months (range, 3 to 80 months). The out-of-field nodal failure when omitting ENI was none. Three patients developed neck recurrences (one in-field recurrence in the 72.6 Gy irradiated nodal area and two in the elective irradiated region of 39.6 Gy). Overall disease failure at any site developed in 11 patients (19.6%). Among these, there were six local failures (10.7%), three regional failures (5.4%), and five distant metastases (8.9%). The 3-year locoregional control rate was 87.1%, and the distant failure-free rate was 90.4%; disease-free survival and overall survival at 3 years was 80% and 86.8%, respectively. No patient developed nodal failure in the omitted ENI site. Our investigation has demonstrated that the reduced volume approach for ENI appears to be a safe treatment approach in NPC

Transient regimes during high-temperature deformation of a bulk metallic glass: A free volume approach

International Nuclear Information System (INIS)

Bletry, M.; Guyot, P.; Brechet, Y.; Blandin, J.J.; Soubeyroux, J.L.

2007-01-01

The homogeneous deformation of a zirconium-based bulk metallic glass is investigated in the glass transition range. Compression and stress-relaxation tests have been conducted. The stress-strain curves are modeled in the framework of the free volume theory, including transient phenomena (overshoot and undershoot). This approach allows several physical parameters (activation volume, flow defect creation and relaxation coefficient) to be determined from a mechanical experiment. This model is able to rationalize the dependency of stress overshoot on relaxation time. It is shown that, due to the relationship between flow defect concentration and free volume model, it is impossible to determine the equilibrium flow defect concentration. However, the relative variation of flow defect is always the same, and all the model parameters depend on the equilibrium flow defect concentration. The methodology presented in this paper should, in the future, allow the consistency of the free volume model to be assessed

High performance liquid chromatography column efficiency enhancement by zero dead volume recycling and practical approach using park and recycle arrangement.

Science.gov (United States)

Minarik, Marek; Franc, Martin; Minarik, Milan

2018-06-15

A new instrumental approach to recycling HPLC is described. The concept is based on fast reintroduction of incremental peak sections back onto the separation column. The re-circulation is performed within a closed loop containing only the column and two synchronized switching valves. By having HPLC pump out of the cycle, the method minimizes peak broadening due to dead volume. As a result the efficiency is dramatically increased allowing for the most demanding analytical applications. In addition, a parking loop is employed for temporary storage of analytes from the middle section of the separated mixture prior to their recycling. Copyright © 2018 Elsevier B.V. All rights reserved.

Cohesive Polydensified Matrix® hyaluronic acid volumizer injected for cheek augmentation has additional positive effect on nasolabial folds

Directory of Open Access Journals (Sweden)

Gauglitz G

2017-12-01

Full Text Available Gerd Gauglitz,1 Stephanie Steckmeier,1 Julian Pötschke,2 Hannah Schwaiger,1 1Department of Dermatology and Allergy, Ludwig-Maximilian University, Munich, Germany; 2Department of Plastic and Hand Surgery, Klinikum St Georg gGmbH, Leipzig, Germany Purpose: Cohesive Polydensified Matrix® hyaluronic acid (CPM-HA volumizer has been used successfully for several years to reverse biometric volume loss during facial aging. This observational study explored the additive effect on nasolabial folds when CPM-HA volumizer is injected into the neighboring cheek area.Patients and methods: In this open-label, prospective, postmarketing noninterventional study, 18 adult patients seeking esthetic enhancement of the lateral cheek hollows and cheekbone area were injected with CPM-HA volumizer integrated with lidocaine (CPM-HA-VL in the upper or lower cheek area. Safety and performance of CPM-HA-VL up to 12 months after injection with follow-up visits at week 4 and month 3, 6, and 12 were assessed. The primary endpoint was improvement of cheek fullness on the validated Merz Aesthetics Scales. Additionally, changes in nasolabial folds were quantified using a phaseshift rapid in vivo measurement of skin optical three-dimensional (3D in vivo measurement device. Results: Patients (94.4% female, median age 52 years, age range 39–69 years were injected with a mean volume of 2.5±1.1 mL CPM-HA-VL per side. Immediately after injection, mean severity for upper and lower cheek fullness assessed on the validated MAS improved from 2.5±0.6 and 2.8±0.5, respectively, to 1.0±0.0, and remained unchanged through month 12. Improvement in relation to baseline was attested on the Global Aesthetics Improvement Scale for all assessments. Compared with baseline, the following assessments offered a statistical significance in the reduction of wrinkle depth of nasolabial folds (maximum depth reduction by 30.4% at 3 months according to optical 3D in vivo measurements. Pain during

Maximum volume cuboids for arbitrarily shaped in-situ rock blocks as determined by discontinuity analysis—A genetic algorithm approach

Science.gov (United States)

Ülker, Erkan; Turanboy, Alparslan

2009-07-01

The block stone industry is one of the main commercial use of rock. The economic potential of any block quarry depends on the recovery rate, which is defined as the total volume of useful rough blocks extractable from a fixed rock volume in relation to the total volume of moved material. The natural fracture system, the rock type(s) and the extraction method used directly influence the recovery rate. The major aims of this study are to establish a theoretical framework for optimising the extraction process in marble quarries for a given fracture system, and for predicting the recovery rate of the excavated blocks. We have developed a new approach by taking into consideration only the fracture structure for maximum block recovery in block quarries. The complete model uses a linear approach based on basic geometric features of discontinuities for 3D models, a tree structure (TS) for individual investigation and finally a genetic algorithm (GA) for the obtained cuboid volume(s). We tested our new model in a selected marble quarry in the town of İscehisar (AFYONKARAHİSAR—TURKEY).

Consequences of additional use of PET information for target volume delineation and radiotherapy dose distribution for esophageal cancer

International Nuclear Information System (INIS)

Muijs, Christina T.; Schreurs, Liesbeth M.; Busz, Dianne M.; Beukema, Jannet C.; Borden, Arnout J. van der; Pruim, Jan; Van der Jagt, Eric J.; Plukker, John Th.; Langendijk, Johannes A.

2009-01-01

Background and purpose: To determine the consequences of target volume (TV) modifications, based on the additional use of PET information, on radiation planning, assuming PET/CT-imaging represents the true extent of the tumour. Materials and methods: For 21 patients with esophageal cancer, two separate TV's were retrospectively defined based on CT (CT-TV) and co-registered PET/CT images (PET/CT-TV). Two 3D-CRT plans (prescribed dose 50.4 Gy) were constructed to cover the corresponding TV's. Subsequently, these plans were compared for target coverage, normal tissue dose-volume histograms and the corresponding normal tissue complication probability (NTCP) values. Results: The addition of PET led to the modification of CT-TV with at least 10% in 12 of 21 patients (57%) (reduction in 9, enlargement in 3). PET/CT-TV was inadequately covered by the CT-based treatment plan in 8 patients (36%). Treatment plan modifications resulted in significant changes (p < 0.05) in dose distributions to heart and lungs. Corresponding changes in NTCP values ranged from -3% to +2% for radiation pneumonitis and from -0.2% to +1.2% for cardiac mortality. Conclusions: This study demonstrated that TV's based on CT might exclude PET-avid disease. Consequences are under dosing and thereby possibly ineffective treatment. Moreover, the addition of PET in radiation planning might result in clinical important changes in NTCP.

The (water + acetonitrile) mixture revisited: A new approach for calculating partial molar volumes

International Nuclear Information System (INIS)

Carmen Grande, Maria del; Julia, Jorge Alvarez; Barrero, Carmen R.; Marschoff, Carlos M.; Bianchi, Hugo L.

2006-01-01

Density and viscosity of (water + acetonitrile) mixtures were measured over the whole composition range at the temperatures: (298.15, 303.15, 308.15, 313.15, and 318.15) K. A new mathematical approach was developed which allows the calculation of the derivatives of density with respect to composition avoiding the appearance of local discontinuities. Thus, reliable partial molar volumes and thermal expansion coefficients were obtained

A topological approach to migration and visualization of time-varying volume data

International Nuclear Information System (INIS)

Fujishiro, Issei; Otsuka, Rieko; Hamaoka, Aya; Takeshima, Yuriko; Takahashi, Shigeo

2004-01-01

Rapid advance in high performance computing and measurement technologies has recently made it possible to produce a stupendous amount of time-varying volume datasets in various disciplines. However, there exist a few known visual exploration tools which allow us to investigate the core of their complex behavior effectively. In this article, our previous approach to topological volume skeletonization is extended to capture the topological skeleton of a 4D volumetric field in terms of critical timing. A cyclic information drilldown scheme, termed T-map, is presented, where a wide choice of information visualization techniques are deployed so that the users are allowed to repeatedly squeeze partial spatiotemporal domains of interest until the size gets fitted into an available computing storage space, prior to topologically-accentuated visualization of the pinpointed volumetric domains. A case study with datasets from atomic collision research is performed to illustrate the feasibility of the present method. (author)

Trans-nipple removal of fibro-glandular tissue in gynaecomastia surgery without additional scars: An innovative approach

Directory of Open Access Journals (Sweden)

R K Mishra

2014-01-01

Full Text Available Context: The established techniques that have been used to treat gynaecomastia are said to have relatively less patient satisfaction rate as they leave some visible scars or mild elevation over the nipple areola complex, resulting in aesthetically unsatisfactory results. Even the slightest elevation or smallest scar over nipple areola complex leave patients extremely self conscious and in a dilemma of having a second intervention to get rid of that blemish. Aims: The aim of the study is to achieve - A flat chest without adding a scar and with no chances of re-occurrence of the condition. This article suggests an innovative approach to address the problem. Materials and Methods: The author presents trans-nipple incision approach for the delivery of fibro-glandular tissue component following liposuction for maximum patient satisfaction. This method consists of a unique small criss-cross incision right on the nipple itself for retrieving any volume of tough fibro-glandular tissues. Between the duration of January 2012 to October 2013, 28 male patients of different ages were operated with this technique. Results: The surgery resulted in well-shaped, symmetric chest contour without any visible elevation or additional scars on nipple areola complex. No complications were noticed in any of the patients. Conclusions: The presented technique is proved to have a high patient satisfaction rate and to be promising method to achieve good aesthetic results in gynaecomastia surgery.

Vocational High School Students’ Creativity in Food Additives with Problem Based Learning Approach

Science.gov (United States)

Ratnasari, D.; Supriyanti, T.; Rosbiono, M.

2017-09-01

The aim of this study is to verify the creativity of vocational students through Problem Based Learning approach in the food additives. The method which used quasi-experiment with one group posttest design. The research subjects were 32 students in grade XII of a vocational high school students courses chemical analysis in Bandung city. Instrument of creativity were essay, Student Worksheet, and observation sheets. Creativity measured include creative thinking skills and creative act skills. The results showed creative thinking skills and creative act skills are good. Research showed that the problem based learning approach can be applied to develop creativity of vocational students in the food additives well, because the students are given the opportunity to determine their own experiment procedure that will be used. It is recommended to often implement Problem Based Learning approach in other chemical concepts so that students’ creativity is sustainable.

A combined volume-of-fluid method and low-Mach-number approach for DNS of evaporating droplets in turbulence

Science.gov (United States)

Dodd, Michael; Ferrante, Antonino

2017-11-01

Our objective is to perform DNS of finite-size droplets that are evaporating in isotropic turbulence. This requires fully resolving the process of momentum, heat, and mass transfer between the droplets and surrounding gas. We developed a combined volume-of-fluid (VOF) method and low-Mach-number approach to simulate this flow. The two main novelties of the method are: (i) the VOF algorithm captures the motion of the liquid gas interface in the presence of mass transfer due to evaporation and condensation without requiring a projection step for the liquid velocity, and (ii) the low-Mach-number approach allows for local volume changes caused by phase change while the total volume of the liquid-gas system is constant. The method is verified against an analytical solution for a Stefan flow problem, and the D2 law is verified for a single droplet in quiescent gas. We also demonstrate the schemes robustness when performing DNS of an evaporating droplet in forced isotropic turbulence.

Introduction to IGRT and additional components

International Nuclear Information System (INIS)

Mijnheer, Ben

2008-01-01

Image-guided radiation therapy is 'Any use of planar imaging, volumetric imaging or volumetric cine imaging, marker localization, marker tracking, patient surface imaging or patient surface tracking to improve the precision of radiation-therapy delivery' , or 'Frequent imaging in the treatment room during a course of radiotherapy to guide the treatment process'. Purpose: To verify if the correct volume in a patient is irradiated by imaging the target and/or healthy tissue prior to or during treatment. Imaging modalities include: Electronic Portal Imaging Devices (EPIDs); (Portal) imaging of implanted markers; Imaging of external markers; Ultrasound; X-ray fluoroscopy; and CT (MR) scanner in treatment room. Final remarks are as follows: The introduction of various IGRT techniques allowed 3D verification of the position of target volumes and organs at risk just before or during treatment. Because the information is in 3D, or sometimes even in 4D, in principle these IGRT approaches provide more information compared to the use of 2D verification methods (e.g. EPIDs). Clinical data are becoming available to assess quantitatively for which treatment techniques IGRT approaches are advantageous compared to the use of conventional verification methods taking the additional resources (time, money, manpower) into account. (P.A.)

Infill Optimization for Additive Manufacturing-Approaching Bone-Like Porous Structures.

Science.gov (United States)

Wu, Jun; Aage, Niels; Westermann, Rudiger; Sigmund, Ole

2018-02-01

Porous structures such as trabecular bone are widely seen in nature. These structures are lightweight and exhibit strong mechanical properties. In this paper, we present a method to generate bone-like porous structures as lightweight infill for additive manufacturing. Our method builds upon and extends voxel-wise topology optimization. In particular, for the purpose of generating sparse yet stable structures distributed in the interior of a given shape, we propose upper bounds on the localized material volume in the proximity of each voxel in the design domain. We then aggregate the local per-voxel constraints by their p-norm into an equivalent global constraint, in order to facilitate an efficient optimization process. Implemented on a high-resolution topology optimization framework, our results demonstrate mechanically optimized, detailed porous structures which mimic those found in nature. We further show variants of the optimized structures subject to different design specifications, and we analyze the optimality and robustness of the obtained structures.

VOXEL-BASED APPROACH FOR ESTIMATING URBAN TREE VOLUME FROM TERRESTRIAL LASER SCANNING DATA

Directory of Open Access Journals (Sweden)

C. Vonderach

2012-07-01

Full Text Available The importance of single trees and the determination of related parameters has been recognized in recent years, e.g. for forest inventories or management. For urban areas an increasing interest in the data acquisition of trees can be observed concerning aspects like urban climate, CO2 balance, and environmental protection. Urban trees differ significantly from natural systems with regard to the site conditions (e.g. technogenic soils, contaminants, lower groundwater level, regular disturbance, climate (increased temperature, reduced humidity and species composition and arrangement (habitus and health status and therefore allometric relations cannot be transferred from natural sites to urban areas. To overcome this problem an extended approach was developed for a fast and non-destructive extraction of branch volume, DBH (diameter at breast height and height of single trees from point clouds of terrestrial laser scanning (TLS. For data acquisition, the trees were scanned with highest scan resolution from several (up to five positions located around the tree. The resulting point clouds (20 to 60 million points are analysed with an algorithm based on voxel (volume elements structure, leading to an appropriate data reduction. In a first step, two kinds of noise reduction are carried out: the elimination of isolated voxels as well as voxels with marginal point density. To obtain correct volume estimates, the voxels inside the stem and branches (interior voxels where voxels contain no laser points must be regarded. For this filling process, an easy and robust approach was developed based on a layer-wise (horizontal layers of the voxel structure intersection of four orthogonal viewing directions. However, this procedure also generates several erroneous "phantom" voxels, which have to be eliminated. For this purpose the previous approach was extended by a special region growing algorithm. In a final step the volume is determined layer-wise based on the

A new approach for calculation of volume confined by ECR surface and its area in ECR ion source

International Nuclear Information System (INIS)

Filippov, A.V.

2007-01-01

The volume confined by the resonance surface and its area are important parameters of the balance equations model for calculation of ion charge-state distribution (CSD) in the electron-cyclotron resonance (ECR) ion source. A new approach for calculation of these parameters is given. This approach allows one to reduce the number of parameters in the balance equations model

Analysing inequalities in Germany a structured additive distributional regression approach

CERN Document Server

Silbersdorff, Alexander

2017-01-01

This book seeks new perspectives on the growing inequalities that our societies face, putting forward Structured Additive Distributional Regression as a means of statistical analysis that circumvents the common problem of analytical reduction to simple point estimators. This new approach allows the observed discrepancy between the individuals’ realities and the abstract representation of those realities to be explicitly taken into consideration using the arithmetic mean alone. In turn, the method is applied to the question of economic inequality in Germany.

October 2015 Phoenix pulmonary journal club: lung volume reduction

Directory of Open Access Journals (Sweden)

Mathew M

2015-11-01

Full Text Available No abstract available. Article truncated at 150 words. The October 2015 pulmonary journal club focused on the review of older studies evaluating lung volume reduction surgery and how this has transitioned toward the development of non-surgical modes of lung volume reduction. The physiology behind dyspnea in chronic obstructive pulmonary disease (COPD is a complex process. One of the proposed mechanisms has been hyperinflation associated with air trapping. In the mid 1990s studies by Cooper and Peterson (1 offered a promising approach in which lung volume reduction (LVR could improve ventilatory mechanics and improve dyspnea. As the procedure gained more popularity, additional larger scale trials were performed to support its validity. We reviewed 2 studies looking at lung volume reduction. The first was "The Effect of Lung Volume Reduction Surgery In Patients With Severe Emphysema” (2 . This was a smaller, randomized controlled trial (RCT that looked at 2 groups of 24 patients. Once group received LVR while the ...

A Rule Based Approach to ISS Interior Volume Control and Layout

Science.gov (United States)

Peacock, Brian; Maida, Jim; Fitts, David; Dory, Jonathan

2001-01-01

Traditional human factors design involves the development of human factors requirements based on a desire to accommodate a certain percentage of the intended user population. As the product is developed human factors evaluation involves comparison between the resulting design and the specifications. Sometimes performance metrics are involved that allow leniency in the design requirements given that the human performance result is satisfactory. Clearly such approaches may work but they give rise to uncertainty and negotiation. An alternative approach is to adopt human factors design rules that articulate a range of each design continuum over which there are varying outcome expectations and interactions with other variables, including time. These rules are based on a consensus of human factors specialists, designers, managers and customers. The International Space Station faces exactly this challenge in interior volume control, which is based on anthropometric, performance and subjective preference criteria. This paper describes the traditional approach and then proposes a rule-based alternative. The proposed rules involve spatial, temporal and importance dimensions. If successful this rule-based concept could be applied to many traditional human factors design variables and could lead to a more effective and efficient contribution of human factors input to the design process.

Prediction of Currency Volume Issued in Taiwan Using a Hybrid Artificial Neural Network and Multiple Regression Approach

Directory of Open Access Journals (Sweden)

Yuehjen E. Shao

2013-01-01

Full Text Available Because the volume of currency issued by a country always affects its interest rate, price index, income levels, and many other important macroeconomic variables, the prediction of currency volume issued has attracted considerable attention in recent years. In contrast to the typical single-stage forecast model, this study proposes a hybrid forecasting approach to predict the volume of currency issued in Taiwan. The proposed hybrid models consist of artificial neural network (ANN and multiple regression (MR components. The MR component of the hybrid models is established for a selection of fewer explanatory variables, wherein the selected variables are of higher importance. The ANN component is then designed to generate forecasts based on those important explanatory variables. Subsequently, the model is used to analyze a real dataset of Taiwan's currency from 1996 to 2011 and twenty associated explanatory variables. The prediction results reveal that the proposed hybrid scheme exhibits superior forecasting performance for predicting the volume of currency issued in Taiwan.

INFLUENCE OF NATURAL ADDITIVES ON PROTEIN COMPLEX OF BREAD

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Dana Urminská

2010-11-01

Full Text Available The study focuses on researching the influence of natural additives on certain technological characteristics of mixtures used for bread production, more particularly the influence of N substances in used raw material on selected qualitative parameters of bread. The blends for bread production to be analysed were prepared by mixing wheat flour with an addition of oat, buckwheat, lentil and chickpea wholegrain flour in different portions (10, 20, 30, 40 and 50 %. The experiment showed that the addition of natural additives worsened the protein complex of the blends used in bread production (worsening also qualitative parameters known as product volume. The loaves prepared with an addition of buckwheat, oat, lentil and chickpea were evaluated to be of a lesser quality from a technological viewpoint when compared with pure wheat loaves. The lower content of gluten forming proteins and the generally changed protein composition of blends due to additives caused a lower percentage of wet gluten content, its lower extensibility and swelling capacity. The sedimentation value (Zeleny index decreased proportionally with the increase of addition until the level was unsatisfactory for raw material intended for bakery purposes. The N content in experimental loaves was higher than in the reference loaves and it increased according to the selected additive and its portion in the blend (more with the addition of lentil and chickpea, less in case of buckwheat and oat which is considered as positive from a nutritional point of view. But from the technological point of view the additives did not show any positive influence and caused a lower loaf bread volume. The most significant decrease of the loaf bread volume was found with the addition of 50 % of buckwheat (- 45.6 %. Better results were obtained with a lower portion of the additive: loaf with an addition of 30 % of chickpea (volume decreased by 12.8 % > loaf with an addition of 30 % of lentil (volume

An improved approach to reduce partial volume errors in brain SPET

International Nuclear Information System (INIS)

Hatton, R.L.; Hatton, B.F.; Michael, G.; Barnden, L.; QUT, Brisbane, QLD; The Queen Elizabeth Hospital, Adelaide, SA

1999-01-01

Full text: Limitations in SPET resolution give rise to significant partial volume error (PVE) in small brain structures We have investigated a previously published method (Muller-Gartner et al., J Cereb Blood Flow Metab 1992;16: 650-658) to correct PVE in grey matter using MRI. An MRI is registered and segmented to obtain a grey matter tissue volume which is then smoothed to obtain resolution matched to the corresponding SPET. By dividing the original SPET with this correction map, structures can be corrected for PVE on a pixel-by-pixel basis. Since this approach is limited by space-invariant filtering, modification was made by estimating projections for the segmented MRI and reconstructing these using identical parameters to SPET. The methods were tested on simulated brain scans, reconstructed with the ordered subsets EM algorithm (8,16, 32, 64 equivalent EM iterations) The new method provided better recovery visually. For 32 EM iterations, recovery coefficients were calculated for grey matter regions. The effects of potential errors in the method were examined. Mean recovery was unchanged with one pixel registration error, the maximum error found in most registration programs. Errors in segmentation > 2 pixels results in loss of accuracy for small structures. The method promises to be useful for reducing PVE in brain SPET

Utilize target motion to cover clinical target volume (ctv) - a novel and practical treatment planning approach to manage respiratory motion

International Nuclear Information System (INIS)

Jin Jianyue; Ajlouni, Munther; Kong Fengming; Ryu, Samuel; Chetty, Indrin J.; Movsas, Benjamin

2008-01-01

Purpose: To use probability density function (PDF) to model motion effects and incorporate this information into treatment planning for lung cancers. Material and methods: PDFs were calculated from the respiratory motion traces of 10 patients. Motion effects were evaluated by convolving static dose distributions with various PDFs. Based on a differential dose prescription with relatively lower dose to the clinical target volume (CTV) than to the gross tumor volume (GTV), two approaches were proposed to incorporate PDFs into treatment planning. The first approach uses the GTV-based internal target volume (ITV) as the planning target volume (PTV) to ensure full dose to the GTV, and utilizes the motion-induced dose gradient to cover the CTV. The second approach employs an inhomogeneous static dose distribution within a minimized PTV to best match the prescription dose gradient. Results: Motion effects on dose distributions were minimal in the anterior-posterior (AP) and lateral directions: a 10-mm motion only induced about 3% of dose reduction in the peripheral target region. The motion effect was remarkable in the cranial-caudal direction. It varied with the motion amplitude, but tended to be similar for various respiratory patterns. For the first approach, a 10-15 mm motion would adequately cover the CTV (presumed to be 60-70% of the GTV dose) without employing the CTV in planning. For motions 15-mm. An example of inhomogeneous static dose distribution in a reduced PTV was given, and it showed significant dose reduction in the normal tissue without compromising target coverage. Conclusions: Respiratory motion-induced dose gradient can be utilized to cover the CTV and minimize the lung dose without the need for more sophisticated technologies

A new MODIS based approach for gas flared volumes estimation: the case of the Val d'Agri Oil Center (Southern Italy)

Science.gov (United States)

Lacava, T.; Faruolo, M.; Coviello, I.; Filizzola, C.; Pergola, N.; Tramutoli, V.

2014-12-01

Gas flaring is one of the most controversial energetic and environmental issues the Earth is facing, moreover contributing to the global warming and climate change. According to the World Bank, each year about 150 Billion Cubic Meter of gas are being flared globally, that is equivalent to the annual gas use of Italy and France combined. Besides, about 400 million tons of CO2 (representing about 1.2% of global CO2 emissions) are added annually into the atmosphere. Efforts to evaluate the impact of flaring on the surrounding environment are hampered by lack of official information on flare locations and volumes. Suitable satellite based techniques could offers a potential solution to this problem through the detection and subsequent mapping of flare locations as well as gas emissions estimation. In this paper a new methodological approach, based on the Robust Satellite Techniques (RST), a multi-temporal scheme of satellite data analysis, was developed to analyze and characterize the flaring activity of the largest Italian gas and oil pre-treatment plant (ENI-COVA) located in Val d'Agri (Basilicata) For this site, located in an anthropized area characterized by a large environmental complexity, flaring emissions are mainly related to emergency conditions (i.e. waste flaring), being the industrial process regulated by strict regional laws. With reference to the peculiar characteristics of COVA flaring, the RST approach was implemented on 13 years of EOS-MODIS (Earth Observing System - Moderate Resolution Imaging Spectroradiometer) infrared data to detect COVA-related thermal anomalies and to develop a regression model for gas flared volume estimation. The methodological approach, the whole processing chain and the preliminarily achieved results will be shown and discussed in this paper. In addition, the possible implementation of the proposed approach on the data acquired by the SUOMI NPP - VIIRS (National Polar-orbiting Partnership - Visible Infrared Imaging

Lanthanum additions and the toughness of ultra-high strength steels and the determination of appropriate lanthanum additions

International Nuclear Information System (INIS)

Garrison, Warren M.; Maloney, James L.

2005-01-01

Studies of commercial heats of AF1410 steel suggest that under appropriate conditions additions of rare-earth elements can significantly enhance fracture toughness. This improvement in toughness is not due to an extremely low inclusion volume fraction but is apparently due to the formation of larger and more widely spaced inclusions. The purpose of this work is to discuss our experience in using rare-earth additions to laboratory scale vacuum induction melted and subsequently vacuum arc remelted heats of ultra-high strength steels to achieve inclusion distributions similar to those observed in commercial heats modified with lanthanum additions. The results indicate that lanthanum additions of 0.015 wt.% to low sulfur steels which have been well deoxidized using carbon-vacuum deoxidation can result in lanthanum rich inclusions which are similar in size, volume fraction and spacing to those obtained in commercially produced heats of ultra-high strength steel to which lanthanum has been added. The heat of steel to which lanthanum additions of 0.015 wt.% were made had significantly higher toughness than did the heat of the same steel in which the sulfur had been gettered as small and closely spaced particles of MnS and which had an inclusion volume fraction similar to that of the heat modified by the addition of 0.015 wt.% lanthanum. This improvement in toughness was attributed to an increase in inclusion spacing. An addition of 0.06 wt.% lanthanum was excessive. Such an addition of lanthanum resulted in a huge volume fraction of large cuboidal inclusions which primarily contain lanthanum and oxygen and which are extremely detrimental to toughness

Economic evaluation of volume reduction for Defense transuranic waste

International Nuclear Information System (INIS)

Brown, C.M.

1982-03-01

The economics of volume reduction of retrievably stored and newly generated DOE transuranic wastes are evaluated by comparing the costs of reduction of the wastes with the savings possible in transportation and disposal. A general approach to the comparison of TRU waste volume reduction costs and cost savings is developed, an initial set of cost data is established, conclusions to support selecting technologies and facilities for the disposal of DOE transuranic waste are developed. Section I outlines the analysis which considers seven types of volume reduction from incineration and compaction of combustibles to compaction, size reduction, shredding, melting, and decontamination of metals. The study considers the volume reduction of contact-handled, newly generated and retrievably stored DOE transuranic wastes. Section II of this report describes the analytical approach, assumptions, and flow of waste material through sites. Section III presents the waste inventories, disposal and transportation savings, and volume reduction techniques and costs. Section IV contains the results and conclusions of the study. The major conclusions drawn from the study are: For DOE sites with a small amount of waste requiring disposal ( 3 /year) the cost of volume reduction is greater than the transportation and disposal savings from volume reduction provided the waste requires little additional preparation to meet transportation and disposal criteria. Wastes that do not meet these criteria require site specific economic analysis outside the general evaluations of this study. For Idaho National Engineering Laboratory, incineration and metal shredding are cost-effective, provided a facility is to be constructed as a consequence of repackaging the fraction of stored waste which may require repackaging and immobilizing chemical process waste to meet disposal criteria

On the form invariant volume transformation in phase space by focusing neutron guides: An analytic treatment

International Nuclear Information System (INIS)

Stüßer, N.; Hofmann, T.

2013-01-01

Tapered guides with supermirror coating are frequently used to focus neutron beams on specimens. The divergence distribution in the focused beam is of a great importance for the quality of neutron instrumentation. Using an analytic approach we derive the tapering which is needed to achieve a form invariant phase space transformation of a rectangular phase volume. In addition we consider the effect of beam attenuation by the finite reflectivity of supermirrors. -- Highlights: • Form invariant volume transformation in phase space. • Focusing modules for neutron beams. • Analytical approach. • Attenuation effects in linearly and nonlinearly tapered guides

Multi-tissue partial volume quantification in multi-contrast MRI using an optimised spectral unmixing approach.

Science.gov (United States)

Collewet, Guylaine; Moussaoui, Saïd; Deligny, Cécile; Lucas, Tiphaine; Idier, Jérôme

2018-06-01

Multi-tissue partial volume estimation in MRI images is investigated with a viewpoint related to spectral unmixing as used in hyperspectral imaging. The main contribution of this paper is twofold. It firstly proposes a theoretical analysis of the statistical optimality conditions of the proportion estimation problem, which in the context of multi-contrast MRI data acquisition allows to appropriately set the imaging sequence parameters. Secondly, an efficient proportion quantification algorithm based on the minimisation of a penalised least-square criterion incorporating a regularity constraint on the spatial distribution of the proportions is proposed. Furthermore, the resulting developments are discussed using empirical simulations. The practical usefulness of the spectral unmixing approach for partial volume quantification in MRI is illustrated through an application to food analysis on the proving of a Danish pastry. Copyright © 2018 Elsevier Inc. All rights reserved.

Extension of the direct statistical approach to a volume parameter model (non-integer splitting)

International Nuclear Information System (INIS)

Burn, K.W.

1990-01-01

The Direct Statistical Approach is a rigorous mathematical derivation of the second moment for surface splitting and Russian Roulette games attached to the Monte Carlo modelling of fixed source particle transport. It has been extended to a volume parameter model (involving non-integer ''expected value'' splitting), and then to a cell model. The cell model gives second moment and time functions that have a closed form. This suggests the possibility of two different methods of solution of the optimum splitting/Russian Roulette parameters. (author)

An on-spot internal standard addition approach for accurately determining colistin A and colistin B in dried blood spots using ultra high-performance liquid chromatography-tandem mass spectrometry.

Science.gov (United States)

Tsai, I-Lin; Kuo, Ching-Hua; Sun, Hsin-Yun; Chuang, Yu-Chung; Chepyala, Divyabharathi; Lin, Shu-Wen; Tsai, Yun-Jung

2017-10-25

Outbreaks of multidrug-resistant Gram-negative bacterial infections have been reported worldwide. Colistin, an antibiotic with known nephrotoxicity and neurotoxicity, is now being used to treat multidrug-resistant Gram-negative strains. In this study, we applied an on-spot internal standard addition approach coupled with an ultra high-performance liquid chromatography-tandem mass spectrometry (LC-MS/MS) method to quantify colistin A and B from dried blood spots (DBSs). Only 15μL of whole blood was required for each sample. An internal standard with the same yield of extraction recoveries as colistin was added to the spot before sample extraction for accurate quantification. Formic acid in water (0.15%) with an equal volume of acetonitrile (50:50v/v) was used as the extraction solution. With the optimized extraction process and LC-MS/MS conditions, colistin A and B could be quantified from a DBS with respective limits of quantification of 0.13 and 0.27μgmL -1 , and the retention times were spot internal standard addition approach which benefited the precision and accuracy. Results showed that DBS sampling coupled with the sensitive LC-MS/MS method has the potential to be an alternative approach for colistin quantification, where the bias of prodrug hydrolysis in liquid samples is decreased. Copyright © 2017 Elsevier B.V. All rights reserved.

Use of Hi-resolution data for evaluating accuracy of traffic volume counts collected by microwave sensors

Directory of Open Access Journals (Sweden)

David K. Chang

2017-10-01

Full Text Available Over the past few years, the Utah Department of Transportation has developed the signal performance metrics (SPMs system to evaluate the performance of signalized intersections dynamically. This system currently provides data summaries for several performance measures, one of them being turning movement counts collected by microwave sensors. As this system became public, there was a need to evaluate the accuracy of the data placed on the SPMs. A large-scale data collection was carried out to meet this need. Vehicles in the Hi-resolution data from microwave sensors were matched with the vehicles by ground-truth volume count data. Matching vehicles from the microwave sensor data and the ground-truth data manually collected required significant effort. A spreadsheet-based data analysis procedure was developed to carry out the task. A mixed model analysis of variance was used to analyze the effects of the factors considered on turning volume count accuracy. The analysis found that approach volume level and number of approach lanes would have significant effect on the accuracy of turning volume counts but the location of the sensors did not significantly affect the accuracy of turning volume counts. In addition, it was found that the location of lanes in relation to the sensor did not significantly affect the accuracy of lane-by-lane volume counts. This indicated that accuracy analysis could be performed by using total approach volumes without comparing specific turning counts, that is, left-turn, through and right-turn movements. In general, the accuracy of approach volume counts collected by microwave sensors were within the margin of error that traffic engineers could accept. The procedure taken to perform the analysis and a summary of accuracy of volume counts for the factor combinations considered are presented in this paper.

Influence of hydrostatic pressure on dynamics and spatial distribution of protein partial molar volume: time-resolved surficial Kirkwood-Buff approach.

Science.gov (United States)

Yu, Isseki; Tasaki, Tomohiro; Nakada, Kyoko; Nagaoka, Masataka

2010-09-30

The influence of hydrostatic pressure on the partial molar volume (PMV) of the protein apomyoglobin (AMb) was investigated by all-atom molecular dynamics (MD) simulations. Using the time-resolved Kirkwood-Buff (KB) approach, the dynamic behavior of the PMV was identified. The simulated time average value of the PMV and its reduction by 3000 bar pressurization correlated with experimental data. In addition, with the aid of the surficial KB integral method, we obtained the spatial distributions of the components of PMV to elucidate the detailed mechanism of the PMV reduction. New R-dependent PMV profiles identified the regions that increase or decrease the PMV under the high pressure condition. The results indicate that besides the hydration in the vicinity of the protein surface, the outer space of the first hydration layer also significantly influences the total PMV change. These results provide a direct and detailed picture of pressure induced PMV reduction.

Molecular dynamics simulation of three plastic additives' diffusion in polyethylene terephthalate.

Science.gov (United States)

Li, Bo; Wang, Zhi-Wei; Lin, Qin-Bao; Hu, Chang-Ying

2017-06-01

Accurate diffusion coefficient data of additives in a polymer are of paramount importance for estimating the migration of the additives over time. This paper shows how this diffusion coefficient can be estimated for three plastic additives [2-(2'-hydroxy-5'-methylphenyl) (UV-P), 2,6-di-tert-butyl-4-methylphenol (BHT) and di-(2-ethylhexyl) phthalate (DEHP)] in polyethylene terephthalate (PET) using the molecular dynamics (MD) simulation method. MD simulations were performed at temperatures of 293-433 K. The diffusion coefficient was calculated through the Einstein relationship connecting the data of mean-square displacement at different times. Comparison of the diffusion coefficients simulated by the MD simulation technique, predicted by the Piringer model and experiments, showed that, except for a few samples, the MD-simulated values were in agreement with the experimental values within one order of magnitude. Furthermore, the diffusion process for additives is discussed in detail, and four factors - the interaction energy between additive molecules and PET, fractional free volume, molecular shape and size, and self-diffusion of the polymer - are proposed to illustrate the microscopic diffusion mechanism. The movement trajectories of additives in PET cell models suggested that the additive molecules oscillate slowly rather than hopping for a long time. Occasionally, when a sufficiently large hole was created adjacently, the molecule could undergo spatial motion by jumping into the free-volume hole and consequently start a continuous oscillation and hop. The results indicate that MD simulation is a useful approach for predicting the microstructure and diffusion coefficient of plastic additives, and help to estimate the migration level of additives from PET packaging.

The volume of a soliton

International Nuclear Information System (INIS)

Adam, C.; Haberichter, M.; Wereszczynski, A.

2016-01-01

There exists, in general, no unique definition of the size (volume, area, etc., depending on dimension) of a soliton. Here we demonstrate that the geometric volume (area etc.) of a soliton is singled out in the sense that it exactly coincides with the thermodynamical or continuum-mechanical volume. In addition, this volume may be defined uniquely for rather arbitrary solitons in arbitrary dimensions.

The volume of a soliton

Energy Technology Data Exchange (ETDEWEB)

Adam, C., E-mail: adam@fpaxp1.usc.es [Departamento de Física de Partículas, Universidad de Santiago de Compostela and Instituto Galego de Física de Altas Enerxias (IGFAE), E-15782 Santiago de Compostela (Spain); Haberichter, M. [School of Mathematics, Statistics and Actuarial Science, University of Kent, Canterbury, CT2 7NF (United Kingdom); Wereszczynski, A. [Institute of Physics, Jagiellonian University, Lojasiewicza 11, Kraków (Poland)

2016-03-10

There exists, in general, no unique definition of the size (volume, area, etc., depending on dimension) of a soliton. Here we demonstrate that the geometric volume (area etc.) of a soliton is singled out in the sense that it exactly coincides with the thermodynamical or continuum-mechanical volume. In addition, this volume may be defined uniquely for rather arbitrary solitons in arbitrary dimensions.

Robust volume calculations for Constructive Solid Geometry (CSG) components in Monte Carlo transport calculations

Energy Technology Data Exchange (ETDEWEB)

Millman, D. L. [Dept. of Computer Science, Univ. of North Carolina at Chapel Hill (United States); Griesheimer, D. P.; Nease, B. R. [Bechtel Marine Propulsion Corporation, Bertis Atomic Power Laboratory (United States); Snoeyink, J. [Dept. of Computer Science, Univ. of North Carolina at Chapel Hill (United States)

2012-07-01

In this paper we consider a new generalized algorithm for the efficient calculation of component object volumes given their equivalent constructive solid geometry (CSG) definition. The new method relies on domain decomposition to recursively subdivide the original component into smaller pieces with volumes that can be computed analytically or stochastically, if needed. Unlike simpler brute-force approaches, the proposed decomposition scheme is guaranteed to be robust and accurate to within a user-defined tolerance. The new algorithm is also fully general and can handle any valid CSG component definition, without the need for additional input from the user. The new technique has been specifically optimized to calculate volumes of component definitions commonly found in models used for Monte Carlo particle transport simulations for criticality safety and reactor analysis applications. However, the algorithm can be easily extended to any application which uses CSG representations for component objects. The paper provides a complete description of the novel volume calculation algorithm, along with a discussion of the conjectured error bounds on volumes calculated within the method. In addition, numerical results comparing the new algorithm with a standard stochastic volume calculation algorithm are presented for a series of problems spanning a range of representative component sizes and complexities. (authors)

Robust volume calculations for Constructive Solid Geometry (CSG) components in Monte Carlo transport calculations

International Nuclear Information System (INIS)

Millman, D. L.; Griesheimer, D. P.; Nease, B. R.; Snoeyink, J.

2012-01-01

In this paper we consider a new generalized algorithm for the efficient calculation of component object volumes given their equivalent constructive solid geometry (CSG) definition. The new method relies on domain decomposition to recursively subdivide the original component into smaller pieces with volumes that can be computed analytically or stochastically, if needed. Unlike simpler brute-force approaches, the proposed decomposition scheme is guaranteed to be robust and accurate to within a user-defined tolerance. The new algorithm is also fully general and can handle any valid CSG component definition, without the need for additional input from the user. The new technique has been specifically optimized to calculate volumes of component definitions commonly found in models used for Monte Carlo particle transport simulations for criticality safety and reactor analysis applications. However, the algorithm can be easily extended to any application which uses CSG representations for component objects. The paper provides a complete description of the novel volume calculation algorithm, along with a discussion of the conjectured error bounds on volumes calculated within the method. In addition, numerical results comparing the new algorithm with a standard stochastic volume calculation algorithm are presented for a series of problems spanning a range of representative component sizes and complexities. (authors)

Use of a theoretical equation of state to interpret time-dependent free volume in polymer glasses

International Nuclear Information System (INIS)

Curro, J.G.; Lagasse, R.R.; Simha, R.

1981-01-01

Many physical properties of polymer glasses change spontaneously during isothermal aging by a process commonly modeled as collapse of free volume. The model has not been verified rigorously because free volume cannot be unambiguously measured. In the present investigation we tentatively identify the free-volume fraction with the fraction of empty sites in the equation of state of Simha and Somcynsky. With this theory, volume recovery measurements can be analyzed to yield directly the time-dependent, free-volume fraction. Using this approach, recent volume measurements on poly(methyl methacrylate) are analyzed. The resulting free-volume fractions are then used in the Doolittle equation to predict the shift in stress relaxation curves at 23 0 C. These predicted shift factors agree with the experimental measurements of Cizmecioglu et al. In addition, it is shown that previous assumptions concerning temperature dependence of free volume are inconsistent with the theory

Limiting volume with modern ventilators.

Science.gov (United States)

Wing, Thomas J; Haan, Lutana; Ashworth, Lonny J; Anderson, Jeff

2015-06-01

The acute respiratory distress syndrome (ARDS) network low tidal-volume study comparing tidal volumes of 12 ml/kg versus 6 ml/kg was published in 2000. The study was stopped early as data revealed a 22% relative reduction in mortality rate when using 6 ml/kg tidal volume. The current generation of critical care ventilators allows the tidal volume to be set during volume-targeted, assist/control (volume A/C); however, some ventilators include options that may prevent the tidal volume from being controlled. The purpose of this bench study was to evaluate the delivered tidal volume, when these options are active, in a spontaneously breathing lung model using an electronic breathing simulator. Four ventilators were evaluated: CareFusion AVEA (AVEA), Dräger Evita® XL (Evita XL), Covidien Puritan Bennett® 840(TM) (PB 840), and Maquet SERVO-i (SERVO-i). Each ventilator was connected to the Hans Rudolph Electronic Breathing Simulator at an amplitude of 0 cm H2O and then 10 cm H2O. All four ventilators were set to deliver volume A/C, tidal volume 400 ml, respiratory rate 20 bpm, positive end-expiratory pressure 5 cm H2O, peak flowrate 60 L/min. The displayed tidal volume was recorded for each ventilator at the above settings with additional options OFF and then ON. The AVEA has two options in volume A/C: demand breaths and V-sync. When activated, these options allow the patient to exceed the set tidal volume. When using the Evita XL, the option AutoFlow can be turned ON or OFF, and when this option is ON, the tidal volume may vary. The PB 840 does not have any additional options that affect volume delivery, and it maintains the set tidal volume regardless of patient effort. The SERVO-i's demand valve allows additional flow if the patient's inspiratory flowrate exceeds the set flowrate, increasing the delivered tidal volume; this option can be turned OFF with the latest software upgrade. Modern ventilators have an increasing number of optional settings. These settings may

Ion diode simulation with a finite-volume PIC approach for the numerical solution of the Maxwell-Lorentz system

Energy Technology Data Exchange (ETDEWEB)

Munz, C D; Schneider, R; Stein, E; Voss, U [Forschungszentrum Karlsruhe (Germany). Institut fuer Neutronenphysik und Reaktortechnik; Westermann, T [FH Karlsruhe (Germany). Fachbereich Naturwissenschaften; Krauss, M [Forschungszentrum Karlsruhe (Germany). Hauptabteilung Informations- und Kommunikationstechik

1997-12-31

The numerical concept realized in the the Karlsruhe Diode Code KADI2D is briefly reviewed. Several new aspects concerning the Maxwell field solver based on high resolution finite-volume methods are presented. A new approach maintaining charge conservation numerically for the Maxwell-Lorentz equations is shortly summarized. (author). 2 figs., 12 refs.

Ion diode simulation with a finite-volume PIC approach for the numerical solution of the Maxwell-Lorentz system

International Nuclear Information System (INIS)

Munz, C.D.; Schneider, R.; Stein, E.; Voss, U.; Westermann, T.; Krauss, M.

1996-01-01

The numerical concept realized in the the Karlsruhe Diode Code KADI2D is briefly reviewed. Several new aspects concerning the Maxwell field solver based on high resolution finite-volume methods are presented. A new approach maintaining charge conservation numerically for the Maxwell-Lorentz equations is shortly summarized. (author). 2 figs., 12 refs

Development of Ethnoscience Approach in The Module Theme Substance Additives to Improve the Cognitive Learning Outcome and Student’s entrepreneurship

Science.gov (United States)

Sudarmin; Febu, R.; Nuswowati, M.; Sumarni, W.

2017-04-01

Ethnoscience approach is an interesting research today. The purpose of this research is to develop approaches ethnoscience and modules ethnoscience theme additives based ethnoscience; as well as assess the feasibility and effectiveness of module theme additives based ethnoscience to improve learning outcomes and the entrepreneurial character of students. This type of research is the Research and Development (R & D). In this research consist of four stages, namely define, design, development and implementation. The subjects of this study were students of the School of MTs Maarif NU Brebes. Data were analyzed by descriptive qualitative and quantitative. The results showed that ethnoscience approach and the module theme substance additives used declared worthy of National Education Standards Agency (BNSP) with an average percentage of validation on the feasibility aspect of the content, language feasibility, and feasibility of presenting respectively for 94.3%, 86 % and 92% and a very decent entry criteria. The effect of the application modules substance additive based ethnoscience can improve on the cognitive learning classical amounted to 90.63%, and increased learning outcomes category was based on the scores of N-gain. Influence ethnoscience approach application and module theme substances additives based ethnoscience able to improve the entrepreneurial character of students. Based on the results of this study concluded that the ethnoscience approach and module theme substance additives based ethnoscience effective to improve learning outcomes and students’ entrepreneurship.

An integrated approach for estimating oil volume in petroleum-contaminated sites: a North American case study

International Nuclear Information System (INIS)

Chen, Z.; Huang, G.H.; Chakma, A.

1999-01-01

An integrated approach for estimating the distribution of light nonaqueous phase liquids (LNAPLs) such as oil spill and leakage in a porous media is proposed, based on a study at a site located in western Canada. The site has one original release source that is a flare pit, with on-site soil and groundwater seriously contaminated by petroleum products spilled over the past two decades. Results of the study show that soil properties and site characteristics have significant impact on the spreading of contaminants which affect the estimation of contaminant volume. Although the LNAPLs in the subsurface do not appear as a distinct layer, and the volume and distribution differ from site to site, the proposed method offers insight into the contamination details and is, therefore, considered to be an effective and convenient tool for obtaining a reasonable estimate of residual oil volume in the subsurface. Results could also be used in designing an enhanced recovery scheme for the site under study, as well as in designing multi-component models of the subsurface contamination for the purpose of risk assessment. 13 refs., 2 tabs., 2 figs

A new approach for implementation of associative memory using volume holographic materials

Science.gov (United States)

Habibi, Mohammad; Pashaie, Ramin

2012-02-01

Associative memory, also known as fault tolerant or content-addressable memory, has gained considerable attention in last few decades. This memory possesses important advantages over the more common random access memories since it provides the capability to correct faults and/or partially missing information in a given input pattern. There is general consensus that optical implementation of connectionist models and parallel processors including associative memory has a better record of success compared to their electronic counterparts. In this article, we describe a novel optical implementation of associative memory which not only has the advantage of all optical learning and recalling capabilities, it can also be realized easily. We present a new approach, inspired by tomographic imaging techniques, for holographic implementation of associative memories. In this approach, a volume holographic material is sandwiched within a matrix of inputs (optical point sources) and outputs (photodetectors). The memory capacity is realized by the spatial modulation of refractive index of the holographic material. Constructing the spatial distribution of the refractive index from an array of known inputs and outputs is formulated as an inverse problem consisting a set of linear integral equations.

Development of a compressive surface capturing formulation for modelling free-surface flow by using the volume-of-fluid approach

CSIR Research Space (South Africa)

Heyns, Johan A

2012-06-01

Full Text Available combines a blended higher resolution scheme with the addition of an artificial compressive term to the volume-of-fluid equation. This reduces the numerical smearing of the interface associated with explicit higher resolution schemes while limiting...

Controllable Microdroplet Splitting via Additional Lateral Flow and its Application in Rapid Synthesis of Multi-scale Microspheres

KAUST Repository

Zhou, Bingpu

2015-01-01

In this paper, we demonstrate that controllable microdroplet splitting could be obtained via additional lateral flow with simplicity and high controllability. The volume ratio of the two splitting products can be flexibly regulated by adjusting the flow rate ratio between the main and additional lateral flows. The splitting phenomena under different main flow rates were investigated. A volume ratio up to 200 : 1 of the two daughter droplets under a relatively higher main flow rate was experimentally achieved based on our approach. In this case, we have successfully achieved uniform daughter droplets with a smallest diameter of ∼19.5 ± 1.6 μm. With such a design, we have synthesized uniform PEGDA hydrogel microspheres with diameters ranging from ∼30 μm to over hundred of micrometers simultaneously.

Linking flood peak, flood volume and inundation extent: a DEM-based approach

Science.gov (United States)

Rebolho, Cédric; Furusho-Percot, Carina; Blaquière, Simon; Brettschneider, Marco; Andréassian, Vazken

2017-04-01

Traditionally, flood inundation maps are computed based on the Shallow Water Equations (SWE) in one or two dimensions, with various simplifications that have proved to give good results. However, the complexity of the SWEs often requires a numerical resolution which can need long computing time, as well as detailed cross section data: this often results in restricting these models to rather small areas abundant with high quality data. This, along with the necessity for fast inundation mapping, are the reason why rapid inundation models are being designed, working for (almost) any river with a minimum amount of data and, above all, easily available data. Our model tries to follow this path by using a 100m DEM over France from which are extracted a drainage network and the associated drainage areas. It is based on two pre-existing methods: (1) SHYREG (Arnaud et al.,2013), a regionalized approach used to calculate the 2-year and 10-year flood quantiles (used as approximated bankfull flow and maximum discharge, respectively) for each river pixel of the DEM (below a 10 000 km2 drainage area) and (2) SOCOSE (Mailhol,1980), which gives, amongst other things, an empirical formula of a characteristic flood duration (for each pixel) based on catchment area, average precipitation and temperature. An overflow volume for each river pixel is extracted from a triangular shaped synthetic hydrograph designed with SHYREG quantiles and SOCOSE flood duration. The volume is then spread from downstream to upstream one river pixel at a time. When the entire hydrographic network is processed, the model stops and generates a map of potential inundation area associated with the 10-year flood quantile. Our model can also be calibrated using past-events inundation maps by adjusting two parameters, one which modifies the overflow duration, and the other, equivalent to a minimum drainage area for river pixels to be flooded. Thus, in calibration on a sample of 42 basins, the first draft of the

Control volume based hydrocephalus research; analysis of human data

Science.gov (United States)

Cohen, Benjamin; Wei, Timothy; Voorhees, Abram; Madsen, Joseph; Anor, Tomer

2010-11-01

Hydrocephalus is a neuropathophysiological disorder primarily diagnosed by increased cerebrospinal fluid volume and pressure within the brain. To date, utilization of clinical measurements have been limited to understanding of the relative amplitude and timing of flow, volume and pressure waveforms; qualitative approaches without a clear framework for meaningful quantitative comparison. Pressure volume models and electric circuit analogs enforce volume conservation principles in terms of pressure. Control volume analysis, through the integral mass and momentum conservation equations, ensures that pressure and volume are accounted for using first principles fluid physics. This approach is able to directly incorporate the diverse measurements obtained by clinicians into a simple, direct and robust mechanics based framework. Clinical data obtained for analysis are discussed along with data processing techniques used to extract terms in the conservation equation. Control volume analysis provides a non-invasive, physics-based approach to extracting pressure information from magnetic resonance velocity data that cannot be measured directly by pressure instrumentation.

3D modeling of forces between magnet and HTS in a levitation system using new approach of the control volume method based on an unstructured grid

Energy Technology Data Exchange (ETDEWEB)

Alloui, L., E-mail: lotfi.alloui@lgep.supelec.fr [Laboratoire de Genie Electrique de Paris - LGEP, CNRS UMR 8507, Supelec, Universite Pierre et Marie Curie-Paris 6, Universite Paris Sud-Paris 11, Plateau de Moulon, 11 rue Joliot Curie, 91192 Gif-Sur-Yvette Cedex (France); Laboratoire de modelisation des systemes energetiques (LMSE), Universite de Biskra, 07000 Biskra (Algeria); Bouillault, F., E-mail: bouillault@lgep.supelec.fr [Laboratoire de Genie Electrique de Paris - LGEP, CNRS UMR 8507, Supelec, Universite Pierre et Marie Curie-Paris 6, Universite Paris Sud-Paris 11, Plateau de Moulon, 11 rue Joliot Curie, 91192 Gif-Sur-Yvette Cedex (France); Bernard, L., E-mail: laurent.bernardl@lgep.supelc.fr [Laboratoire de Genie Electrique de Paris - LGEP, CNRS UMR 8507, Supelec, Universite Pierre et Marie Curie-Paris 6, Universite Paris Sud-Paris 11, Plateau de Moulon, 11 rue Joliot Curie, 91192 Gif-Sur-Yvette Cedex (France); Leveque, J., E-mail: jean.leveque@green.uhp-nancy.fr [Groupe de recherche en electronique et electrotechnique de Nancy, Universite Henry Poincare, BP 239, 54506 Vandoeuvre les Nancy (France)

2012-05-15

In this paper we present new 3D numerical model to calculate the vertical and the guidance forces in high temperature superconductors taking into account the influence of the flux creep phenomena. In the suggested numerical model, we adopt a new approach of the control volume method. This approach is based on the use of an unstructured grid which can be used to model more complex geometries. A comparison of the control volume method results with experiments verifies the validity of this approach and the proposed numerical model. Based on this model, the levitation force's relaxation at different temperatures was also studied.

Additional disturbances as a beneficial tool for restoration of post-mining sites: a multi-taxa approach.

Science.gov (United States)

Řehounková, Klára; Čížek, Lukáš; Řehounek, Jiří; Šebelíková, Lenka; Tropek, Robert; Lencová, Kamila; Bogusch, Petr; Marhoul, Pavel; Máca, Jan

2016-07-01

Open interior sands represent a highly threatened habitat in Europe. In recent times, their associated organisms have often found secondary refuges outside their natural habitats, mainly in sand pits. We investigated the effects of different restoration approaches, i.e. spontaneous succession without additional disturbances, spontaneous succession with additional disturbances caused by recreational activities, and forestry reclamation, on the diversity and conservation values of spiders, beetles, flies, bees and wasps, orthopterans and vascular plants in a large sand pit in the Czech Republic, Central Europe. Out of 406 species recorded in total, 112 were classified as open sand specialists and 71 as threatened. The sites restored through spontaneous succession with additional disturbances hosted the largest proportion of open sand specialists and threatened species. The forestry reclamations, in contrast, hosted few such species. The sites with spontaneous succession without disturbances represent a transition between these two approaches. While restoration through spontaneous succession favours biodiversity in contrast to forestry reclamation, additional disturbances are necessary to maintain early successional habitats essential for threatened species and open sand specialists. Therefore, recreational activities seem to be an economically efficient restoration tool that will also benefit biodiversity in sand pits.

Eleven fetal echocardiographic planes using 4-dimensional ultrasound with spatio-temporal image correlation (STIC): a logical approach to fetal heart volume analysis.

Science.gov (United States)

Jantarasaengaram, Surasak; Vairojanavong, Kittipong

2010-09-15

Theoretically, a cross-sectional image of any cardiac planes can be obtained from a STIC fetal heart volume dataset. We described a method to display 11 fetal echocardiographic planes from STIC volumes. Fetal heart volume datasets were acquired by transverse acquisition from 200 normal fetuses at 15 to 40 weeks of gestation. Analysis of the volume datasets using the described technique to display 11 echocardiographic planes in the multiplanar display mode were performed offline. Volume datasets from 18 fetuses were excluded due to poor image resolution. The mean visualization rates for all echocardiographic planes at 15-17, 18-22, 23-27, 28-32 and 33-40 weeks of gestation fetuses were 85.6% (range 45.2-96.8%, N = 31), 92.9% (range 64.0-100%, N = 64), 93.4% (range 51.4-100%, N = 37), 88.7%(range 54.5-100%, N = 33) and 81.8% (range 23.5-100%, N = 17) respectively. Overall, the applied technique can favorably display the pertinent echocardiographic planes. Description of the presented method provides a logical approach to explore the fetal heart volumes.

Quasi-chemical approach for adsorption of mixtures with non-additive lateral interactions

Energy Technology Data Exchange (ETDEWEB)

Pinto, O.A. [Instituto de Bionanotecnología (INBIONATEC-CONICET), Universidad Nacional de Santiago de Estero, RN 9 Km 1125 Villa el Zanjón, Santiago del Estero G4206XCP (Argentina); Pasinetti, P.M., E-mail: pmp@unsl.edu.ar [Departamento de Física, Instituto de Física Aplicada (INFAP), Universidad Nacional de San Luis—CONICET, Ejército de los Andes 950, D5700BWS San Luis (Argentina); Ramirez-Pastor, A.J. [Departamento de Física, Instituto de Física Aplicada (INFAP), Universidad Nacional de San Luis—CONICET, Ejército de los Andes 950, D5700BWS San Luis (Argentina)

2017-01-15

Highlights: • The classical quasi-chemical approach is generalized to model non-additive mixtures. • The formalism allows to obtain the partial isotherms and the differential heat of adsorption. • A rich variety of low-temperature phases is observed in the adsorbed layer. • Theoretical results show a good agreement with Monte Carlo simulations. - Abstract: The statistical thermodynamics of binary mixtures with non-additive lateral interactions was developed on a generalization in the spirit of the lattice-gas model and the classical quasi-chemical approximation (QCA). The traditional assumption of a strictly pairwise additive nearest-neighbors interaction is replaced by a more general one, namely that the bond linking a certain atom with any of its neighbors depends considerably on how many of them are actually present (or absent) on the sites in the first coordination shell of the atom. The total and partial adsorption isotherms are given for both attractive and repulsive lateral interactions between the adsorbed species. Interesting behaviors are observed and discussed in terms of the low-temperature phases formed in the system. Comparisons with Monte Carlo simulations are performed in order to test the validity of the theoretical model.

Design for volume reduction

NARCIS (Netherlands)

Wever, R.; Boks, C.; Stevels, A.

2007-01-01

Traditionally packaging design-for-sustainability (DfS) strongly focuses on resource conservation and material recycling. The type and amount of materials used has been the driver in design. For consumer electronics (CE) products this weight-based approach is too limited; a volume-based approach is

Volume Ray Casting with Peak Finding and Differential Sampling

KAUST Repository

Knoll, A.

2009-11-01

Direct volume rendering and isosurfacing are ubiquitous rendering techniques in scientific visualization, commonly employed in imaging 3D data from simulation and scan sources. Conventionally, these methods have been treated as separate modalities, necessitating different sampling strategies and rendering algorithms. In reality, an isosurface is a special case of a transfer function, namely a Dirac impulse at a given isovalue. However, artifact-free rendering of discrete isosurfaces in a volume rendering framework is an elusive goal, requiring either infinite sampling or smoothing of the transfer function. While preintegration approaches solve the most obvious deficiencies in handling sharp transfer functions, artifacts can still result, limiting classification. In this paper, we introduce a method for rendering such features by explicitly solving for isovalues within the volume rendering integral. In addition, we present a sampling strategy inspired by ray differentials that automatically matches the frequency of the image plane, resulting in fewer artifacts near the eye and better overall performance. These techniques exhibit clear advantages over standard uniform ray casting with and without preintegration, and allow for high-quality interactive volume rendering with sharp C0 transfer functions. © 2009 IEEE.

Industrial experience feedback of a geostatistical estimation of contaminated soil volumes - 59181

International Nuclear Information System (INIS)

Faucheux, Claire; Jeannee, Nicolas

2012-01-01

Geo-statistics meets a growing interest for the remediation forecast of potentially contaminated sites, by providing adapted methods to perform both chemical and radiological pollution mapping, to estimate contaminated volumes, potentially integrating auxiliary information, and to set up adaptive sampling strategies. As part of demonstration studies carried out for GeoSiPol (Geo-statistics for Polluted Sites), geo-statistics has been applied for the detailed diagnosis of a former oil depot in France. The ability within the geo-statistical framework to generate pessimistic / probable / optimistic scenarios for the contaminated volumes allows a quantification of the risks associated to the remediation process: e.g. the financial risk to excavate clean soils, the sanitary risk to leave contaminated soils in place. After a first mapping, an iterative approach leads to collect additional samples in areas previously identified as highly uncertain. Estimated volumes are then updated and compared to the volumes actually excavated. This benchmarking therefore provides a practical feedback on the performance of the geo-statistical methodology. (authors)

Volume definition system for treatment planning

International Nuclear Information System (INIS)

Alakuijala, Jyrki; Pekkarinen, Ari; Puurunen, Harri

1997-01-01

Purpose: Volume definition is a difficult and time consuming task in 3D treatment planning. We have studied a systems approach for constructing an efficient and reliable set of tools for volume definition. Our intent is to automate body outline, air cavities and bone volume definition and accelerate definition of other anatomical structures. An additional focus is on assisting in definition of CTV and PTV. The primary goals of this work are to cut down the time used in contouring and to improve the accuracy of volume definition. Methods: We used the following tool categories: manual, semi-automatic, automatic, structure management, target volume definition, and visualization tools. The manual tools include mouse contouring tools with contour editing possibilities and painting tools with a scaleable circular brush and an intelligent brush. The intelligent brush adapts its shape to CT value boundaries. The semi-automatic tools consist of edge point chaining, classical 3D region growing of single segment and competitive volume growing of multiple segments. We tuned the volume growing function to take into account both local and global region image values, local volume homogeneity, and distance. Heuristic seeding followed with competitive volume growing finds the body outline, couch and air automatically. The structure management tool stores ICD-O coded structures in a database. The codes have predefined volume growing parameters and thus are able to accommodate the volume growing dissimilarity function for different volume types. The target definition tools include elliptical 3D automargin for CTV to PTV transformation and target volume interpolation and extrapolation by distance transform. Both the CTV and the PTV can overlap with anatomical structures. Visualization tools show the volumes as contours or color wash overlaid on an image and displays voxel rendering or translucent triangle mesh rendering in 3D. Results: The competitive volume growing speeds up the

Numerical modelling in building thermo-aeraulics: from CFD modelling to an hybrid finite volume / zonal approach; Modelisation numerique de la thermoaeraulique du batiment: des modeles CFD a une approche hybride volumes finis / zonale

Energy Technology Data Exchange (ETDEWEB)

Bellivier, A.

2004-05-15

For 3D modelling of thermo-aeraulics in building using field codes, it is necessary to reduce the computing time in order to model increasingly larger volumes. The solution suggested in this study is to couple two modelling: a zonal approach and a CFD approach. The first part of the work that was carried out is the setting of a simplified CFD modelling. We propose rules for use of coarse grids, a constant effective viscosity law and adapted coefficients for heat exchange in the framework of building thermo-aeraulics. The second part of this work concerns the creation of fluid Macro-Elements and their coupling with a calculation of CFD finite volume type. Depending on the boundary conditions of the problem, a local description of the driving flow is proposed via the installation and use of semi-empirical evolution laws. The Macro-Elements is then inserted in CFD computation: the values of velocity calculated by the evolution laws are imposed on the CFD cells corresponding to the Macro-Element. We use these two approaches on five cases representative of thermo-aeraulics in buildings. The results are compared with experimental data and with traditional RANS simulations. We highlight the significant gain of time that our approach allows while preserving a good quality of numerical results. (author)

Comparing Volumes of Prisms and Pyramids

Science.gov (United States)

Vinogradova, Natalya

2012-01-01

Students' experience in using formulas for volumes is often limited to substituting numbers into given formulas. An activity presented in this article may help students make connections between the formulas for volumes of prisms and volumes of pyramids. In addition, some interesting facts from number theory arise, demonstrating strong connections…

Environmental report 1995. Volume 2

International Nuclear Information System (INIS)

Harrach, R.J.; Failor, R.A.; Gallegos, G.M.

1996-09-01

This is Volume 2 of the Lawrence Livermore National Laboratory's (LLNL's) annual Environmental Report 1995. This volume is intended to support summary data from Volume 1 and is essentially a detailed data report that provides additional data points, where applicable. Some summary data are also included in Volume 2, and more detailed accounts are given of sample collection and analytical methods. Volume 2 includes information in eight chapters on monitoring of air, air effluent, sewage, surface water, ground water, soil and sediment, vegetation and foodstuff, and environmental radiation, as well as three chapters on ground water protection, compliance self-monitoring and quality assurance

Transitioning to the direct anterior approach in total hip arthroplasty. Is it a true muscle sparing approach when performed by a low volume hip replacement surgeon?

Science.gov (United States)

Nistor, Dan-Viorel; Caterev, Sergiu; Bolboacă, Sorana-Daniela; Cosma, Dan; Lucaciu, Dan Osvald Gheorghe; Todor, Adrian

2017-11-01

We conducted this study to establish if the transition from a lateral approach (LA) to the direct anterior approach (DAA) for a low volume hip arthroplasty surgeon during the steep learning curve can be performed maintaining the muscle sparing approach of the DAA without increasing the complication rates. In this controlled, prospective, randomized clinical study we investigated 70 patients (35 DAA, 35 LA) with similar demographics that underwent a total hip arthroplasty. Assessment of the two approaches consisted of determining the invasiveness through serum markers for muscle damage (i.e. myoglobin, creatine kinase and lactate dehydrogenase), the operative parameters such as post-operative pain and rescue medication consumption, the component positioning and complication rates. Post-operative myoglobin levels were higher (p < 0.001) in the LA group (326.42 ± 84.91 ng/mL) as compared to the DAA group (242.80 ± 71.03 ng/mL), but with no differences regarding other biomarkers for muscle damage. Pain levels were overall lower in the DAA group, with a statistical and clinical difference during surgery day (p < 0.001) associated with lower (p < 0.001) rescue medication consumption (median 1 (1; 3) mg morphine vs. 3 (2; 4) mg morphine). Most patients in the LA group reported chronic post-operative pain throughout all three evaluated months, while the majority of patients in the DAA group reported no pain after week six. Component positioning did not differ significantly between groups and neither did complication rates. The DAA can be transitioned from the LA safely, without higher complication rates while maintaining its muscle spearing advantages when performed by a low volume hip arthroplasty surgeon.

Investigation of Adaptive-threshold Approaches for Determining Area-Time Integrals from Satellite Infrared Data to Estimate Convective Rain Volumes

Science.gov (United States)

Smith, Paul L.; VonderHaar, Thomas H.

1996-01-01

The principal goal of this project is to establish relationships that would allow application of area-time integral (ATI) calculations based upon satellite data to estimate rainfall volumes. The research is being carried out as a collaborative effort between the two participating organizations, with the satellite data analysis to determine values for the ATIs being done primarily by the STC-METSAT scientists and the associated radar data analysis to determine the 'ground-truth' rainfall estimates being done primarily at the South Dakota School of Mines and Technology (SDSM&T). Synthesis of the two separate kinds of data and investigation of the resulting rainfall-versus-ATI relationships is then carried out jointly. The research has been pursued using two different approaches, which for convenience can be designated as the 'fixed-threshold approach' and the 'adaptive-threshold approach'. In the former, an attempt is made to determine a single temperature threshold in the satellite infrared data that would yield ATI values for identifiable cloud clusters which are closely related to the corresponding rainfall amounts as determined by radar. Work on the second, or 'adaptive-threshold', approach for determining the satellite ATI values has explored two avenues: (1) attempt involved choosing IR thresholds to match the satellite ATI values with ones separately calculated from the radar data on a case basis; and (2) an attempt involved a striaghtforward screening analysis to determine the (fixed) offset that would lead to the strongest correlation and lowest standard error of estimate in the relationship between the satellite ATI values and the corresponding rainfall volumes.

Reduce in Variation and Improve Efficiency of Target Volume Delineation by a Computer-Assisted System Using a Deformable Image Registration Approach

International Nuclear Information System (INIS)

Chao, K.S. Clifford; Bhide, Shreerang FRCR; Chen, Hansen; Asper, Joshua PAC; Bush, Steven; Franklin, Gregg; Kavadi, Vivek; Liengswangwong, Vichaivood; Gordon, William; Raben, Adam; Strasser, Jon; Koprowski, Christopher; Frank, Steven; Chronowski, Gregory; Ahamad, Anesa; Malyapa, Robert; Zhang Lifei; Dong Lei

2007-01-01

Purpose: To determine whether a computer-assisted target volume delineation (CAT) system using a deformable image registration approach can reduce the variation of target delineation among physicians with different head and neck (HN) IMRT experiences and reduce the time spent on the contouring process. Materials and Methods: We developed a deformable image registration method for mapping contours from a template case to a patient case with a similar tumor manifestation but different body configuration. Eight radiation oncologists with varying levels of clinical experience in HN IMRT performed target delineation on two HN cases, one with base-of-tongue (BOT) cancer and another with nasopharyngeal cancer (NPC), by first contouring from scratch and then by modifying the contours deformed by the CAT system. The gross target volumes were provided. Regions of interest for comparison included the clinical target volumes (CTVs) and normal organs. The volumetric and geometric variation of these regions of interest and the time spent on contouring were analyzed. Results: We found that the variation in delineating CTVs from scratch among the physicians was significant, and that using the CAT system reduced volumetric variation and improved geometric consistency in both BOT and NPC cases. The average timesaving when using the CAT system was 26% to 29% for more experienced physicians and 38% to 47% for the less experienced ones. Conclusions: A computer-assisted target volume delineation approach, using a deformable image-registration method with template contours, was able to reduce the variation among physicians with different experiences in HN IMRT while saving contouring time

Surface plasmon polariton nanocavity with ultrasmall mode volume

Science.gov (United States)

Yue, Wencheng; Yao, Peijun; Luo, Huiwen; Liu, Wen

2017-08-01

We present a plasmonic nanocavity structure, consisting of a gallium phosphide (GaP) cylinder penetrating into a rectangular silver plate, and study its properties using a finite element method (FEM). An ultrasmall mode volume of 1.5×10-5[λ_0/(2n)]3 is achieved, which is more than 200 times smaller than the previous ultrasmall mode volume plasmonic nanodisk resonators. Meanwhile, the quality factor of the plasmonic nanocavity is about 38.2 and is over two times greater than the ultrasmall mode volume plasmonic nanodisk resonators. Compared to the aforementioned plasmonic nanodisk resonators, a more than one-order of magnitude larger Purcell factor of 1.2×104 is achieved. We determined the resonant modes of our plasmonic nanocavity are dipolar plasmon modes by analyzing the electric field properties. In addition, we investigate the dependence of the optical properties on the refractive index of the cavity material and discuss the effect of including the silica (SiO2) substrate. Our work provides an alternative approach to achieve ultrasmall plasmonic nanocavity of interest in applications to many areas of research, including device physics, nonlinear optics and quantum optics.

Generalised additive modelling approach to the fermentation process of glutamate.

Science.gov (United States)

Liu, Chun-Bo; Li, Yun; Pan, Feng; Shi, Zhong-Ping

2011-03-01

In this work, generalised additive models (GAMs) were used for the first time to model the fermentation of glutamate (Glu). It was found that three fermentation parameters fermentation time (T), dissolved oxygen (DO) and oxygen uptake rate (OUR) could capture 97% variance of the production of Glu during the fermentation process through a GAM model calibrated using online data from 15 fermentation experiments. This model was applied to investigate the individual and combined effects of T, DO and OUR on the production of Glu. The conditions to optimize the fermentation process were proposed based on the simulation study from this model. Results suggested that the production of Glu can reach a high level by controlling concentration levels of DO and OUR to the proposed optimization conditions during the fermentation process. The GAM approach therefore provides an alternative way to model and optimize the fermentation process of Glu. Crown Copyright © 2010. Published by Elsevier Ltd. All rights reserved.

Kinetics approach to modeling of polymer additive degradation in lubricants

Institute of Scientific and Technical Information of China (English)

llyaI.KUDISH; RubenG.AIRAPETYAN; Michael; J.; COVITCH

2001-01-01

A kinetics problem for a degrading polymer additive dissolved in a base stock is studied.The polymer degradation may be caused by the combination of such lubricant flow parameters aspressure, elongational strain rate, and temperature as well as lubricant viscosity and the polymercharacteristics (dissociation energy, bead radius, bond length, etc.). A fundamental approach tothe problem of modeling mechanically induced polymer degradation is proposed. The polymerdegradation is modeled on the basis of a kinetic equation for the density of the statistical distribu-tion of polymer molecules as a function of their molecular weight. The integrodifferential kineticequation for polymer degradation is solved numerically. The effects of pressure, elongational strainrate, temperature, and lubricant viscosity on the process of lubricant degradation are considered.The increase of pressure promotes fast degradation while the increase of temperature delaysdegradation. A comparison of a numerically calculated molecular weight distribution with an ex-perimental one obtained in bench tests showed that they are in excellent agreement with eachother.

The dose-volume constraint satisfaction problem for inverse treatment planning with field segments

International Nuclear Information System (INIS)

Michalski, Darek; Xiao, Ying; Censor, Yair; Galvin, James M

2004-01-01

The prescribed goals of radiation treatment planning are often expressed in terms of dose-volume constraints. We present a novel formulation of a dose-volume constraint satisfaction search for the discretized radiation therapy model. This approach does not rely on any explicit cost function. Inverse treatment planning uses the aperture-based approach with predefined, according to geometric rules, segmental fields. The solver utilizes the simultaneous version of the cyclic subgradient projection algorithm. This is a deterministic iterative method designed for solving the convex feasibility problems. A prescription is expressed with the set of inequalities imposed on the dose at the voxel resolution. Additional constraint functions control the compliance with selected points of the expected cumulative dose-volume histograms. The performance of this method is tested on prostate and head-and-neck cases. The relationships with other models and algorithms of similar conceptual origin are discussed. The demonstrated advantages of the method are: the equivalence of the algorithmic and prescription parameters, the intuitive setup of free parameters, and the improved speed of the method as compared to similar iterative as well as other techniques. The technique reported here will deliver approximate solutions for inconsistent prescriptions

Automatic tumour volume delineation in respiratory-gated PET images

International Nuclear Information System (INIS)

Gubbi, Jayavardhana; Palaniswami, Marimuthu; Kanakatte, Aparna; Mani, Nallasamy; Kron, Tomas; Binns, David; Srinivasan, Bala

2011-01-01

Positron emission tomography (PET) is a state-of-the-art functional imaging technique used in the accurate detection of cancer. The main problem with the tumours present in the lungs is that they are non-stationary during each respiratory cycle. Tumours in the lungs can get displaced up to 2.5 cm during respiration. Accurate detection of the tumour enables avoiding the addition of extra margin around the tumour that is usually used during radiotherapy treatment planning. This paper presents a novel method to detect and track tumour in respiratory-gated PET images. The approach followed to achieve this task is to automatically delineate the tumour from the first frame using support vector machines. The resulting volume and position information from the first frame is used in tracking its motion in the subsequent frames with the help of level set (LS) deformable model. An excellent accuracy of 97% is obtained using wavelets and support vector machines. The volume calculated as a result of the machine learning (ML) stage is used as a constraint for deformable models and the tumour is tracked in the remaining seven phases of the respiratory cycle. As a result, the complete information about tumour movement during each respiratory cycle is available in relatively short time. The combination of the LS and ML approach accurately delineated the tumour volume from all frames, thereby providing a scope of using PET images towards planning an accurate and effective radiotherapy treatment for lung cancer.

Large-Scale Multi-Resolution Representations for Accurate Interactive Image and Volume Operations

KAUST Repository

Sicat, Ronell B.

2015-11-25

and voxel footprints in input images and volumes. We show that the continuous pdfs encoded in the sparse pdf map representation enable accurate multi-resolution non-linear image operations on gigapixel images. Similarly, we show that sparse pdf volumes enable more consistent multi-resolution volume rendering compared to standard approaches, on both artificial and real world large-scale volumes. The supplementary videos demonstrate our results. In the standard approach, users heavily rely on panning and zooming interactions to navigate the data within the limits of their display devices. However, panning across the whole spatial domain and zooming across all resolution levels of large-scale images to search for interesting regions is not practical. Assisted exploration techniques allow users to quickly narrow down millions to billions of possible regions to a more manageable number for further inspection. However, existing approaches are not fully user-driven because they typically already prescribe what being of interest means. To address this, we introduce the patch sets representation for large-scale images. Patches inside a patch set are grouped and encoded according to similarity via a permutohedral lattice (p-lattice) in a user-defined feature space. Fast set operations on p-lattices facilitate patch set queries that enable users to describe what is interesting. In addition, we introduce an exploration framework—GigaPatchExplorer—for patch set-based image exploration. We show that patch sets in our framework are useful for a variety of user-driven exploration tasks in gigapixel images and whole collections thereof.

Effect of fructo-oligosaccharide and isomalto-oligosaccharide addition on baking quality of frozen dough.

Science.gov (United States)

Park, Eun Young; Jang, Sung-Bum; Lim, Seung-Taik

2016-12-15

The baking quality of frozen doughs containing different levels of fructo-oligosaccharides (FO) or isomalto-oligosaccharides (IMO) (3-9%, w/w flour), and stored for 0-8weeks at -18°C, was examined. The addition of FO or IMO increased the proof volume of the dough and the loaf volume of bread prepared from frozen dough. A 6% addition of FO or IMO was optimum, giving the highest proof volume and bread loaf volume, but a higher concentration than 6% induced low baking quality including lower proof volume and bread loaf volume. The bread crumb was moister and softer after the addition of FO or IMO before, and even after, frozen storage. Darker crumb colour was observed in the bread after the addition of FO or IMO. The oligosaccharides added to the frozen dough were effective in improving the quality of bread made from frozen dough, except for resulting in a darker bread crumb. Copyright © 2016. Published by Elsevier Ltd.

Process-Structure Linkages Using a Data Science Approach: Application to Simulated Additive Manufacturing Data

International Nuclear Information System (INIS)

Popova, Evdokia; Rodgers, Theron M.; Gong, Xinyi; Cecen, Ahmet; Madison, Jonathan D.; Kalidindi, Surya R.

2017-01-01

A novel data science workflow is developed and demonstrated to extract process-structure linkages (i.e., reduced-order model) for microstructure evolution problems when the final microstructure depends on (simulation or experimental) processing parameters. Our workflow consists of four main steps: data pre-processing, microstructure quantification, dimensionality reduction, and extraction/validation of process-structure linkages. These methods that can be employed within each step vary based on the type and amount of available data. In this paper, this data-driven workflow is applied to a set of synthetic additive manufacturing microstructures obtained using the Potts-kinetic Monte Carlo (kMC) approach. Additive manufacturing techniques inherently produce complex microstructures that can vary significantly with processing conditions. Using the developed workflow, a low-dimensional data-driven model was established to correlate process parameters with the predicted final microstructure. In addition, the modular workflows developed and presented in this work facilitate easy dissemination and curation by the broader community.

The concurrent multiplicative-additive approach for gauge-radar/satellite multisensor precipitation estimates

Science.gov (United States)

Garcia-Pintado, J.; Barberá, G. G.; Erena Arrabal, M.; Castillo, V. M.

2010-12-01

Objective analysis schemes (OAS), also called ``succesive correction methods'' or ``observation nudging'', have been proposed for multisensor precipitation estimation combining remote sensing data (meteorological radar or satellite) with data from ground-based raingauge networks. However, opposite to the more complex geostatistical approaches, the OAS techniques for this use are not optimized. On the other hand, geostatistical techniques ideally require, at the least, modelling the covariance from the rain gauge data at every time step evaluated, which commonly cannot be soundly done. Here, we propose a new procedure (concurrent multiplicative-additive objective analysis scheme [CMA-OAS]) for operational rainfall estimation using rain gauges and meteorological radar, which does not require explicit modelling of spatial covariances. On the basis of a concurrent multiplicative-additive (CMA) decomposition of the spatially nonuniform radar bias, within-storm variability of rainfall and fractional coverage of rainfall are taken into account. Thus both spatially nonuniform radar bias, given that rainfall is detected, and bias in radar detection of rainfall are handled. The interpolation procedure of CMA-OAS is built on the OAS, whose purpose is to estimate a filtered spatial field of the variable of interest through a successive correction of residuals resulting from a Gaussian kernel smoother applied on spatial samples. The CMA-OAS, first, poses an optimization problem at each gauge-radar support point to obtain both a local multiplicative-additive radar bias decomposition and a regionalization parameter. Second, local biases and regionalization parameters are integrated into an OAS to estimate the multisensor rainfall at the ground level. The approach considers radar estimates as background a priori information (first guess), so that nudging to observations (gauges) may be relaxed smoothly to the first guess, and the relaxation shape is obtained from the sequential

Post-mortem virtual estimation of free abdominal blood volume

International Nuclear Information System (INIS)

Ampanozi, Garyfalia; Hatch, Gary M.; Ruder, Thomas D.; Flach, Patricia M.; Germerott, Tanja; Thali, Michael J.; Ebert, Lars C.

2012-01-01

Purpose: The purpose of this retrospective study was to examine the reliability of virtually estimated abdominal blood volume using segmentation from postmortem computed tomography (PMCT) data. Materials and methods: Twenty-one cases with free abdominal blood were investigated by PMCT and autopsy. The volume of the blood was estimated using a manual segmentation technique (Amira, Visage Imaging, Germany) and the results were compared to autopsy data. Six of 21 cases had undergone additional post-mortem computed tomographic angiography (PMCTA). Results: The virtually estimated abdominal blood volumes did not differ significantly from those measured at autopsy. Additional PMCTA did not bias data significantly. Conclusion: Virtual estimation of abdominal blood volume is a reliable technique. The virtual blood volume estimation is a useful tool to deliver additional information in cases where autopsy is not performed or in cases where a postmortem angiography is performed

A true minimally invasive approach for cochlear implantation: high accuracy in cranial base navigation through flat-panel-based volume computed tomography.

Science.gov (United States)

Majdani, Omid; Bartling, Soenke H; Leinung, Martin; Stöver, Timo; Lenarz, Minoo; Dullin, Christian; Lenarz, Thomas

2008-02-01

High-precision intraoperative navigation using high-resolution flat-panel volume computed tomography makes feasible the possibility of minimally invasive cochlear implant surgery, including cochleostomy. Conventional cochlear implant surgery is typically performed via mastoidectomy with facial recess to identify and avoid damage to vital anatomic landmarks. To accomplish this procedure via a minimally invasive approach--without performing mastoidectomy--in a precise fashion, image-guided technology is necessary. With such an approach, surgical time and expertise may be reduced, and hearing preservation may be improved. Flat-panel volume computed tomography was used to scan 4 human temporal bones. A drilling channel was planned preoperatively from the mastoid surface to the round window niche, providing a margin of safety to all functional important structures (e.g., facial nerve, chorda tympani, incus). Postoperatively, computed tomographic imaging and conventional surgical exploration of the drilled route to the cochlea were performed. All 4 specimens showed a cochleostomy located at the scala tympani anterior inferior to the round window. The chorda tympani was damaged in 1 specimen--this was preoperatively planned as a narrow facial recess was encountered. Using flat-panel volume computed tomography for image-guided surgical navigation, we were able to perform minimally invasive cochlear implant surgery defined as a narrow, single-channel mastoidotomy with cochleostomy. Although this finding is preliminary, it is technologically achievable.

Gastric Adenocarcinoma: A Multimodal Approach

Directory of Open Access Journals (Sweden)

Humair S. Quadri

2017-08-01

Full Text Available Despite its declining incidence, gastric cancer (GC remains a leading cause of cancer-related deaths worldwide. A multimodal approach to GC is critical to ensure optimal patient outcomes. Pretherapy fine resolution contrast-enhanced cross-sectional imaging, endoscopic ultrasound and staging laparoscopy play an important role in patients with newly diagnosed ostensibly operable GC to avoid unnecessary non-therapeutic laparotomies. Currently, margin negative gastrectomy and adequate lymphadenectomy performed at high volume hospitals remain the backbone of GC treatment. Importantly, adequate GC surgery should be integrated in the setting of a multimodal treatment approach. Treatment for advanced GC continues to expand with the emergence of additional lines of systemic and targeted therapies.

Three-dimensional reconstruction volume: a novel method for volume measurement in kidney cancer.

Science.gov (United States)

Durso, Timothy A; Carnell, Jonathan; Turk, Thomas T; Gupta, Gopal N

2014-06-01

The role of volumetric estimation is becoming increasingly important in the staging, management, and prognostication of benign and cancerous conditions of the kidney. We evaluated the use of three-dimensional reconstruction volume (3DV) in determining renal parenchymal volumes (RPV) and renal tumor volumes (RTV). We compared 3DV with the currently available methods of volume assessment and determined its interuser reliability. RPV and RTV were assessed in 28 patients who underwent robot-assisted laparoscopic partial nephrectomy for kidney cancer. Patients with a preoperative creatinine level of kidney pre- and postsurgery overestimated 3D reconstruction volumes by 15% to 102% and 12% to 101%, respectively. In addition, volumes obtained from 3DV displayed high interuser reliability regardless of experience. 3DV provides a highly reliable way of assessing kidney volumes. Given that 3DV takes into account visible anatomy, the differences observed using previously published methods can be attributed to the failure of geometry to accurately approximate kidney or tumor shape. 3DV provides a more accurate, reproducible, and clinically useful tool for urologists looking to improve patient care using analysis related to volume.

Guidelines for selecting codes for ground-water transport modeling of low-level waste burial sites. Volume 1. Guideline approach

Energy Technology Data Exchange (ETDEWEB)

Simmons, C.S.; Cole, C.R.

1985-05-01

This document was written for the National Low-Level Waste Management Program to provide guidance for managers and site operators who need to select ground-water transport codes for assessing shallow-land burial site performance. The guidance given in this report also serves the needs of applications-oriented users who work under the direction of a manager or site operator. The guidelines are published in two volumes designed to support the needs of users having different technical backgrounds. An executive summary, published separately, gives managers and site operators an overview of the main guideline report. This volume includes specific recommendations for decision-making managers and site operators on how to use these guidelines. The more detailed discussions about the code selection approach are provided. 242 refs., 6 figs.

Guidelines for selecting codes for ground-water transport modeling of low-level waste burial sites. Volume 1. Guideline approach

International Nuclear Information System (INIS)

Simmons, C.S.; Cole, C.R.

1985-05-01

This document was written for the National Low-Level Waste Management Program to provide guidance for managers and site operators who need to select ground-water transport codes for assessing shallow-land burial site performance. The guidance given in this report also serves the needs of applications-oriented users who work under the direction of a manager or site operator. The guidelines are published in two volumes designed to support the needs of users having different technical backgrounds. An executive summary, published separately, gives managers and site operators an overview of the main guideline report. This volume includes specific recommendations for decision-making managers and site operators on how to use these guidelines. The more detailed discussions about the code selection approach are provided. 242 refs., 6 figs

3D prostate TRUS segmentation using globally optimized volume-preserving prior.

Science.gov (United States)

Qiu, Wu; Rajchl, Martin; Guo, Fumin; Sun, Yue; Ukwatta, Eranga; Fenster, Aaron; Yuan, Jing

2014-01-01

An efficient and accurate segmentation of 3D transrectal ultrasound (TRUS) images plays an important role in the planning and treatment of the practical 3D TRUS guided prostate biopsy. However, a meaningful segmentation of 3D TRUS images tends to suffer from US speckles, shadowing and missing edges etc, which make it a challenging task to delineate the correct prostate boundaries. In this paper, we propose a novel convex optimization based approach to extracting the prostate surface from the given 3D TRUS image, while preserving a new global volume-size prior. We, especially, study the proposed combinatorial optimization problem by convex relaxation and introduce its dual continuous max-flow formulation with the new bounded flow conservation constraint, which results in an efficient numerical solver implemented on GPUs. Experimental results using 12 patient 3D TRUS images show that the proposed approach while preserving the volume-size prior yielded a mean DSC of 89.5% +/- 2.4%, a MAD of 1.4 +/- 0.6 mm, a MAXD of 5.2 +/- 3.2 mm, and a VD of 7.5% +/- 6.2% in - 1 minute, deomonstrating the advantages of both accuracy and efficiency. In addition, the low standard deviation of the segmentation accuracy shows a good reliability of the proposed approach.

The dependence of prostate postimplant dosimetric quality on CT volume determination

International Nuclear Information System (INIS)

Merrick, Gregory S.; Butler, Wayne M.; Dorsey, Anthony T.; Lief, Jonathan H.

1999-01-01

Purpose: The postoperative evaluation of permanent prostate brachytherapy requires a subjective determination of the implant volume. This work investigates the magnitude of the effect that various methods of treatment volume delineation have on dosimetric quality parameters for a treatment planning philosophy that defines a target volume as the prostate with a periprostatic margin. Methods and Materials: Eight consecutive prostate brachytherapy patients with a prescribed dose of 145 Gy from 125 I as monotherapy comprised the study population. The prostate ultrasound volume was enlarged to a planning volume by an average factor of 1.8 to encompass probable extracapsular extension in the periprostatic region. For this cohort, the mean pretreatment parameters were 30.3 cm 3 ultrasound volume, 51.8 cm 3 planning volume, 131 seeds per patient, and 42.9 mCi total activity. On CT study sets obtained less than 2 hours postoperatively, target volumes were drawn using three methods: prostate plus a periprostatic margin, prostate only which excluded the puborectalis muscles, the periprostatic fat and the periprostatic venous plexus, and the preplanning ultrasound magnified to conform to the magnification factor of the postimplant CT scan. Three sets of 5 dosimetric quality parameters corresponding to the different volumetric approaches were calculated: V100, V150, and V200 which are the fractions of the target volume covered by 100, 150, and 200% of the prescribed dose, and D90 and D100, which are the minimal doses covering 90 and 100% of the target volume. Results: The postoperative CT volume utilizing the prostate plus margin technique was comparable to the initial planning volume (mean 55.5 cm 3 vs. 51.8 cm 3 , respectively) whereas those determined via superimposing the preplan ultrasound resulted in volumes nearly identical to the initial ultrasound evaluation (mean 32.4 cm 3 vs. 30.3 cm 3 ). The prostate only approach resulted in volumes approximately 25% larger than

PENERAPAN PENDEKATAN KONTEKSTUAL TERHADAP PENGUASAAN KONSEP DASAR MATERI VOLUME BENDA PUTAR

Directory of Open Access Journals (Sweden)

Alpha Galih Adirakasiwi

2018-02-01

Full Text Available ABSTRACTThe purpose of this study was determine the application of contextual teaching learning approach to improve the mastery of concepts volume of the rotary object. The study design was nonequivalent pretest-posttest control group design. Data collection technique used pretest and posttest to determine the mastery of concepts of volume of the rotary object. Hypothesis testing using t-test to compare the the mastery of concepts volume of the rotary object in the experimental class and control class, then a further test by comparing the mean (compare means and average absolute gain Based on the research result the data show that it can be concluded that the approach of contextual learning significantly distinction of concepts volume of the rotary object. Keywords:  Contextual Teaching Learning Approach, The Mastery of Concepts, Volume of The Rotary Object

Effect on the operation properties of DMBR with the addition of GAC

Science.gov (United States)

Lin, Jizhi; Zhang, Qian; Hong, Junming

2017-01-01

The membrane bioreactor and dynamic membrane bioreactor were used to examine the effect of granular activated carbon (GAC) on the treatment of synthetic wastewater. After the addition of different volume fractions GAC in the DMBR, the operation parameters, effluent COD, NH4 +-N, NO3 --N, TN concentrations and sludge viscosity of the bioreactor was investigated. The results showed that the addition of GAC could relieve the membrane fouling and improve the removal efficiencies of pollutants in the DMBR. The effluent concentrations of pollutants were linear correlation with the addition of volume fractions of GAC in the bioreactor. The value of R2 of each modulation was almost more than 0.9. The sludge viscosity was almost not affected by the volume fractions of GAC in the bioreactor. The best volume fractions of GAC were 20% in the DMBR.

Coyote Papers: The University of Arizona Working Papers in Linguistics, Volume 11. Special Volume on Native American Languages.

Science.gov (United States)

Weinberg, Jessica P., Ed.; O'Bryan, Erin L., Ed.; Moll, Laura A., Ed.; Haugan, Jason D., Ed.

The five papers included in this volume approach the study of American Indian languages from a diverse array of methodological and theoretical approaches to linguistics. Two papers focus on approaches that come from the applied linguistics tradition, emphasizing ethnolinguistics and discourse analysis: Sonya Bird's paper "A Cross Cultural…

Flow characteristics of metallic powder grains for additive manufacturing

Directory of Open Access Journals (Sweden)

Peters Bernhard

2017-01-01

Full Text Available Directed energy deposition technologies for additive manufacturing such as laser selective melting (SLM or electron beam melting (EBM is a fast growing technique mainly due to its flexibility in product design. However, the process is a complex interaction of multi-physics on multiple length scales that are still not entirely understood. A particular challenging task are the flow characteristics of metallic powder ejected as jets from a nozzle and shielded by an inert turbulent gas flow. Therefore, the objective is to describe numerically the complex interaction between turbulent flow and powder grains. In order to include both several physical processes and length scales an Euler-Lagrange technology is applied. Within this framework powder is treated by the Discrete-Element-Method, while gas flow is described by Euler approaches as found in classical Computational Fluid Dynamics (CFD. The described method succeeded in delivering more accuracy and consistency than a standard approach based on the volume averaging technique and therefore, is suited for the solution of problems within an engineering framework.

Transform coding for hardware-accelerated volume rendering.

Science.gov (United States)

Fout, Nathaniel; Ma, Kwan-Liu

2007-01-01

Hardware-accelerated volume rendering using the GPU is now the standard approach for real-time volume rendering, although limited graphics memory can present a problem when rendering large volume data sets. Volumetric compression in which the decompression is coupled to rendering has been shown to be an effective solution to this problem; however, most existing techniques were developed in the context of software volume rendering, and all but the simplest approaches are prohibitive in a real-time hardware-accelerated volume rendering context. In this paper we present a novel block-based transform coding scheme designed specifically with real-time volume rendering in mind, such that the decompression is fast without sacrificing compression quality. This is made possible by consolidating the inverse transform with dequantization in such a way as to allow most of the reprojection to be precomputed. Furthermore, we take advantage of the freedom afforded by off-line compression in order to optimize the encoding as much as possible while hiding this complexity from the decoder. In this context we develop a new block classification scheme which allows us to preserve perceptually important features in the compression. The result of this work is an asymmetric transform coding scheme that allows very large volumes to be compressed and then decompressed in real-time while rendering on the GPU.

Additive effects of gastric volumes and macronutrient composition on the sensation of postprandial fullness in humans.

Science.gov (United States)

Marciani, L; Cox, E F; Pritchard, S E; Major, G; Hoad, C L; Mellows, M; Hussein, M O; Costigan, C; Fox, M; Gowland, P A; Spiller, R C

2015-03-01

Intake of food or fluid distends the stomach and triggers mechanoreceptors and vagal afferents. Wall stretch and tension produces a feeling of fullness. Duodenal infusion studies assessing gastric sensitivity by barostat have shown that the products of fat digestion have a greater effect on the sensation of fullness and also dyspeptic symptoms than carbohydrates. We tested here the hypothesis that fat and carbohydrate have different effects on gastric sensation under physiological conditions using non-invasive magnetic resonance imaging (MRI) to measure gastric volumes. Thirteen healthy subjects received a rice pudding test meal with added fat or added carbohydrate on two separate occasions and underwent serial postprandial MRI scans for 4.5 h. Fullness was assessed on a 100-mm visual analogue scale. Gastric half emptying time was significantly slower for the high-carbohydrate meal than for the high-fat meal, P=0.0327. Fullness significantly correlated with gastric volumes for both meals; however, the change from baseline in fullness scores was higher for the high-fat meal for any given change in stomach volume (P=0.0147), despite the lower energy content and faster gastric emptying of the high-fat meal. Total gastric volume correlates positively and linearly with postprandial fullness and ingestion of a high-fat meal increases this sensation compared with high-carbohydrate meal. These findings can be of clinical interest in patients presenting with postprandial dyspepsia whereby manipulating gastric sensitivity by dietary intervention may help to control digestive sensations.

Left ventricular volume analysis as a basic tool to describe cardiac function.

Science.gov (United States)

Kerkhof, Peter L M; Kuznetsova, Tatiana; Ali, Rania; Handly, Neal

2018-03-01

The heart is often regarded as a compression pump. Therefore, determination of pressure and volume is essential for cardiac function analysis. Traditionally, ventricular performance was described in terms of the Starling curve, i.e., output related to input. This view is based on two variables (namely, stroke volume and end-diastolic volume), often studied in the isolated (i.e., denervated) heart, and has dominated the interpretation of cardiac mechanics over the last century. The ratio of the prevailing coordinates within that paradigm is termed ejection fraction (EF), which is the popular metric routinely used in the clinic. Here we present an insightful alternative approach while describing volume regulation by relating end-systolic volume (ESV) to end-diastolic volume. This route obviates the undesired use of metrics derived from differences or ratios, as employed in previous models. We illustrate basic principles concerning ventricular volume regulation by data obtained from intact animal experiments and collected in healthy humans. Special attention is given to sex-specific differences. The method can be applied to the dynamics of a single heart and to an ensemble of individuals. Group analysis allows for stratification regarding sex, age, medication, and additional clinically relevant covariates. A straightforward procedure derives the relationship between EF and ESV and describes myocardial oxygen consumption in terms of ESV. This representation enhances insight and reduces the impact of the metric EF, in favor of the end-systolic elastance concept advanced 4 decades ago.

Reinforced soil structures. Volume II, Summary of research and systems information

Science.gov (United States)

1989-11-01

Volume II was essentially prepared as an Appendix of supporting information for Volume I. This volume contains much of the supporting theory and a summary of the research used to verify the design approach contained in Volume I, as well as general in...

Thermal modelling of extrusion based additive manufacturing of composite materials

DEFF Research Database (Denmark)

Jensen, Mathias Laustsen; Sonne, Mads Rostgaard; Hattel, Jesper Henri

One of the hottest topics regarding manufacturing these years is additive manufacturing (AM). AM is a young branch of manufacturing techniques, which by nature is disruptive due to its completely different manufacturing approach, wherein material is added instead of removed. By adding material...... layer by layer, mould and customised tooling requirements from the conventional manufacturing are reduced or removed, which leads to increased customisation options and enables new part complexities without increasing the manufacturing cost. AM hence enables customised small volume productions...... of composite parts not feasible by conventional manufacturing techniques. This sets up new requirements to the part verification and validation, while conventional destructive tests become too expensive. This initial study aims to investigate alternative options to this destructive testing by increasing...

Sample volume and alignment analysis for an optical particle counter sizer, and other applications

International Nuclear Information System (INIS)

Holve, D.J.; Davis, G.W.

1985-01-01

Optical methods for particle size distribution measurements in practical high temperature environments are approaching feasibility and offer significant advantages over conventional sampling methods. A key requirement of single particle counting techniques is the need to know features of the sample volume intensity distribution which in general are a function of the particle scattering properties and optical system geometry. In addition, the sample volume intensity distribution is sensitive to system alignment and thus calculations of alignment sensitivity are required for assessment of practical alignment tolerances. To this end, an analysis of sample volume characteristics for single particle counters in general has been developed. Results from the theory are compared with experimental measurements and shown to be in good agreement. A parametric sensitivity analysis is performed and a criterion for allowable optical misalignment is derived for conditions where beam steering caused by fluctuating refractive-index gradients is significant

Spatiotemporal radiotherapy planning using a global optimization approach

Science.gov (United States)

Adibi, Ali; Salari, Ehsan

2018-02-01

This paper aims at quantifying the extent of potential therapeutic gain, measured using biologically effective dose (BED), that can be achieved by altering the radiation dose distribution over treatment sessions in fractionated radiotherapy. To that end, a spatiotemporally integrated planning approach is developed, where the spatial and temporal dose modulations are optimized simultaneously. The concept of equivalent uniform BED (EUBED) is used to quantify and compare the clinical quality of spatiotemporally heterogeneous dose distributions in target and critical structures. This gives rise to a large-scale non-convex treatment-plan optimization problem, which is solved using global optimization techniques. The proposed spatiotemporal planning approach is tested on two stylized cancer cases resembling two different tumor sites and sensitivity analysis is performed for radio-biological and EUBED parameters. Numerical results validate that spatiotemporal plans are capable of delivering a larger BED to the target volume without increasing the BED in critical structures compared to conventional time-invariant plans. In particular, this additional gain is attributed to the irradiation of different regions of the target volume at different treatment sessions. Additionally, the trade-off between the potential therapeutic gain and the number of distinct dose distributions is quantified, which suggests a diminishing marginal gain as the number of dose distributions increases.

Generalized Partial Volume

DEFF Research Database (Denmark)

Darkner, Sune; Sporring, Jon

2011-01-01

Mutual Information (MI) and normalized mutual information (NMI) are popular choices as similarity measure for multimodal image registration. Presently, one of two approaches is often used for estimating these measures: The Parzen Window (PW) and the Generalized Partial Volume (GPV). Their theoret...... of view as well as w.r.t. computational complexity. Finally, we present algorithms for both approaches for NMI which is comparable in speed to Sum of Squared Differences (SSD), and we illustrate the differences between PW and GPV on a number of registration examples....

Gross tumor volume and clinical target volume: soft-tissue sarcoma of the extremities

International Nuclear Information System (INIS)

Lartigau, E.; Kantor, G.; Lagarde, P.; Taieb, S.; Ceugnart, L.; Vilain, M.O.; Penel, N.; Depadt, G.

2001-01-01

Soft tissue sarcomas of the extremities are currently treated with more conservative and functional approaches, combining surgery, radiotherapy and chemotherapy. The role of external beam radiotherapy and brachytherapy has been defined through randomized studies performed in the 80's and 90's. However, the ubiquity of tumour location for these tumours makes difficult a systematic definition of local treatments. Tumour volume definition is based on pre and post surgical imaging (MRI) and on described pathological report. The clinical target volume will take into account quality of the resection and anatomical barriers and will be based on an anatomy and not only on safety margins around the tumour bed. General rules for this irradiation (doses, volumes) and principal results will be presented. (authors)

Shared Communications: Volume 2. In-Depth Systems Research

Energy Technology Data Exchange (ETDEWEB)

Truett, LF

2004-09-22

This report is the second of two documents that examine the literature for actual examples of organizations and agencies that share communications resources. While the primary emphasis is on rural, intelligent transportation system (ITS) communications involving transit, examples will not be limited to rural activities, nor to ITS implementation, nor even to transit. In addition, the term ''communication'' will be broadly applied to include all information resources. The first document of this series, ''Shared Communications: Volume I. A Summary and Literature Review'', defines the meaning of the term ''shared communication resources'' and provides many examples of agencies that share resources. This document, ''Shared Communications: Volume II. In-Depth Systems Research'', reviews attributes that contributed to successful applications of the sharing communication resources concept. A few examples of each type of communication sharing are provided. Based on the issues and best practice realworld examples, recommendations for potential usage and recommended approaches for field operational tests are provided.

A data-driven approach for modeling post-fire debris-flow volumes and their uncertainty

Science.gov (United States)

Friedel, Michael J.

2011-01-01

This study demonstrates the novel application of genetic programming to evolve nonlinear post-fire debris-flow volume equations from variables associated with a data-driven conceptual model of the western United States. The search space is constrained using a multi-component objective function that simultaneously minimizes root-mean squared and unit errors for the evolution of fittest equations. An optimization technique is then used to estimate the limits of nonlinear prediction uncertainty associated with the debris-flow equations. In contrast to a published multiple linear regression three-variable equation, linking basin area with slopes greater or equal to 30 percent, burn severity characterized as area burned moderate plus high, and total storm rainfall, the data-driven approach discovers many nonlinear and several dimensionally consistent equations that are unbiased and have less prediction uncertainty. Of the nonlinear equations, the best performance (lowest prediction uncertainty) is achieved when using three variables: average basin slope, total burned area, and total storm rainfall. Further reduction in uncertainty is possible for the nonlinear equations when dimensional consistency is not a priority and by subsequently applying a gradient solver to the fittest solutions. The data-driven modeling approach can be applied to nonlinear multivariate problems in all fields of study.

An integrated simulator of structure and anisotropic flow in gas diffusion layers with hydrophobic additives

Science.gov (United States)

Burganos, Vasilis N.; Skouras, Eugene D.; Kalarakis, Alexandros N.

2017-10-01

The lattice-Boltzmann (LB) method is used in this work to reproduce the controlled addition of binder and hydrophobicity-promoting agents, like polytetrafluoroethylene (PTFE), into gas diffusion layers (GDLs) and to predict flow permeabilities in the through- and in-plane directions. The present simulator manages to reproduce spreading of binder and hydrophobic additives, sequentially, into the neat fibrous layer using a two-phase flow model. Gas flow simulation is achieved by the same code, sidestepping the need for a post-processing flow code and avoiding the usual input/output and data interface problems that arise in other techniques. Compression effects on flow anisotropy of the impregnated GDL are also studied. The permeability predictions for different compression levels and for different binder or PTFE loadings are found to compare well with experimental data for commercial GDL products and with computational fluid dynamics (CFD) predictions. Alternatively, the PTFE-impregnated structure is reproduced from Scanning Electron Microscopy (SEM) images using an independent, purely geometrical approach. A comparison of the two approaches is made regarding their adequacy to reproduce correctly the main structural features of the GDL and to predict anisotropic flow permeabilities at different volume fractions of binder and hydrophobic additives.

Defining Investment Additionality for CDM projects - practical approaches

International Nuclear Information System (INIS)

Greiner, Sandra; Michaelowa, Axel

2003-01-01

The environmental integrity of the CDM under the Kyoto Protocol depends on the possibility to avoid giving emission credits to projects that would have happened anyway. Whether and how 'Investment Additionality' of CDM projects has to be determined is currently a part of climate negotiations. We discuss the rationale of companies to invest in projects and analyse possible criteria to determine Investment Additionality from a theoretical point of view. Differences in the type of investment call for the application of different criteria. Although some criteria are better than others, no single criterion can outweigh the others in all respects. We therefore suggest a scheme for additionality testing that aims at matching types of investment and criteria in a sensible way. Criteria are evaluated on the grounds of robustness to manipulation, degree of coverage and appropriateness for testing the investment decision under consideration

76 FR 21418 - Fiscal Year 2011 Allocation of Additional Tariff-Rate Quota Volume for Raw Cane Sugar and...

Science.gov (United States)

2011-04-15

...-Rate Quota Volume for Raw Cane Sugar and Reallocation of Unused Fiscal Year 2011 Tariff-Rate Quota Volume for Raw Cane Sugar AGENCY: Office of the United States Trade Representative. ACTION: Notice...) for imported raw cane sugar and of country-by-country reallocations of the FY 2011 in-quota quantity...

77 FR 25012 - Fiscal Year 2012 Allocation of Additional Tariff-Rate Quota Volume for Raw Cane Sugar and...

Science.gov (United States)

2012-04-26

...-Rate Quota Volume for Raw Cane Sugar and Reallocation of Unused Fiscal Year 2012 Tariff-Rate Quota Volume for Raw Cane Sugar AGENCY: Office of the United States Trade Representative. ACTION: Notice...) for imported raw cane sugar and of country-by-country reallocations of the FY 2012 in-quota quantity...

Safety assessment methodologies for near surface disposal facilities. Results of a co-ordinated research project (ISAM). Volume 1: Review and enhancement of safety assessment approaches and tools. Volume 2: Test cases

International Nuclear Information System (INIS)

2004-07-01

For several decades, countries have made use of near surface facilities for the disposal of low and intermediate level radioactive waste. In line with the internationally agreed principles of radioactive waste management, the safety of these facilities needs to be ensured during all stages of their lifetimes, including the post-closure period. By the mid 1990s, formal methodologies for evaluating the long term safety of such facilities had been developed, but intercomparison of these methodologies had revealed a number of discrepancies between them. Consequently, in 1997, the International Atomic Energy Agency launched a Co-ordinated Research Project (CRP) on Improvement of Safety Assessment Methodologies for Near Surface Disposal Facilities (ISAM). The particular objectives of the CRP were to provide a critical evaluation of the approaches and tools used in post-closure safety assessment for proposed and existing near-surface radioactive waste disposal facilities, enhance the approaches and tools used and build confidence in the approaches and tools used. The CRP ran until 2000 and resulted in the development of a harmonized assessment methodology (the ISAM project methodology), which was applied to a number of test cases. Over seventy participants from twenty-two Member States played an active role in the project and it attracted interest from around seven hundred persons involved with safety assessment in seventy-two Member States. The results of the CRP have contributed to the Action Plan on the Safety of Radioactive Waste Management which was approved by the Board of Governors and endorsed by the General Conference in September 2001. Specifically, they contribute to Action 5, which requests the IAEA Secretariat to 'develop a structured and systematic programme to ensure adequate application of the Agency's waste safety standards', by elaborating on the Safety Requirements on 'Near Surface Disposal of Radioactive Waste' (Safety Standards Series No. WS-R-1) and

Influence of calcium acetate on rye bread volume

Directory of Open Access Journals (Sweden)

Katharina FUCKERER

2016-01-01

Full Text Available Abstract The positive accepted savoury taste of rye bread is dependent on acetate concentration in the dough of such breads. In order to study how calcium acetate influences rye bread properties, the pH of rye doughs fortified with calcium acetate and the resulting volume of the breads were measured. Furthermore, CO2 formation of yeast with added calcium acetate and yeast with different pH levels (4, 7, 9 were measured. Thereby, it was determined that the addition of calcium acetate increased the pH of dough from 4.42 to 5.29 and significantly reduced the volume of the breads from 1235.19 mL to 885.52 mL. It could be proven that bread volume was affected by a 30.9% lower CO2 amount production of yeast, although bread volume was not affected by changing pH levels. Due to reduced bread volume, high concentrations of calcium acetate additions are not recommended for improving rye bread taste.

Spatial and temporal variation of residence time and storage volume of subsurface water evaluated by multi-tracers approach in mountainous headwater catchments

Science.gov (United States)

Tsujimura, Maki; Yano, Shinjiro; Abe, Yutaka; Matsumoto, Takehiro; Yoshizawa, Ayumi; Watanabe, Ysuhito; Ikeda, Koichi

2015-04-01

Headwater catchments in mountainous region are the most important recharge area for surface and subsurface waters, additionally time and stock information of the water is principal to understand hydrological processes in the catchments. However, there have been few researches to evaluate variation of residence time and storage volume of subsurface water in time and space at the mountainous headwaters especially with steep slope. We performed an investigation on age dating and estimation of storage volume using simple water budget model in subsurface water with tracing of hydrological flow processes in mountainous catchments underlain by granite, Paleozoic and Tertiary, Yamanashi and Tsukuba, central Japan. We conducted hydrometric measurements and sampling of spring, stream and ground waters in high-flow and low-flow seasons from 2008 through 2012 in the catchments, and CFCs, stable isotopic ratios of oxygen-18 and deuterium, inorganic solute constituent concentrations were determined on all water samples. Residence time of subsurface water ranged from 11 to 60 years in the granite catchments, from 17 to 32 years in the Paleozoic catchments, from 13 to 26 years in the Tertiary catchments, and showed a younger age during the high-flow season, whereas it showed an older age in the low-flow season. Storage volume of subsurface water was estimated to be ranging from 10 ^ 4 to 10 ^ 6 m3 in the granite catchments, from 10 ^ 5 to 10 ^ 7 m3 in the Paleozoic catchments, from 10 ^ 4 to 10 ^ 6 m3 in the Tertiary catchments. In addition, seasonal change of storage volume in the granite catchments was the highest as compared with those of the Paleozoic and the Tertiary catchments. The results suggest that dynamic change of hydrological process seems to cause a larger variation of the residence time and storage volume of subsurface water in time and space in the granite catchments, whereas higher groundwater recharge rate due to frequent fissures or cracks seems to cause larger

Stroke infarct volume estimation in fixed tissue

DEFF Research Database (Denmark)

Bay, Vibeke; Kjølby, Birgitte F; Iversen, Nina K

2018-01-01

be investigated in fixed tissue and therefore allows a more direct comparison between lesion volumes from MRI and histology. Additionally, the larger MKT infarct lesion indicates that MKT do provide increased sensitivity to microstructural changes in the lesion area compared to MD....... and prepared. The infarct was clearly visible in both MD and MKT maps. The MKT lesion volume was roughly 31% larger than the MD lesion volume. Subsequent histological analysis (hematoxylin) revealed similar lesion volumes to MD. Our study shows that structural components underlying the MD/MKT mismatch can...

Application of the Price-Volume Approach in Cases of Innovative Drugs Where Value-Based Pricing is Inadequate: Description of Real Experiences in Italy.

Science.gov (United States)

Messori, Andrea

2016-08-01

Several cases of expensive drugs designed for large patient populations (e.g. sofosbuvir) have raised a complex question in terms of drug pricing. Even assuming value-based pricing, the treatment with these drugs of all eligible patients would have an immense budgetary impact, which is unsustainable also for the richest countries. This raises the need to reduce the prices of these agents in comparison with those suggested by the value-based approach and to devise new pricing methods that can achieve this goal. The present study discusses in detail the following two methods: (i) The approach based on setting nation-wide budget thresholds for individual innovative agents in which a fixed proportion of the historical pharmaceutical expenditure represents the maximum budget attributable to an innovative treatment; (ii) The approach based on nation-wide price-volume agreements in which drug prices are progressively reduced as more patients receive the treatment. The first approach has been developed in the USA by the Institute for Clinical and Economic Review and has been applied to PCSK9 inhibitors (alirocumab and evolocumab). The second approach has been designed for the Italian market and has found a systematic application to manage the price of ranibizumab, sofosbuvir, and PCSK9 inhibitors. While, in the past, price-volume agreements have been applied only on an empirical basis (i.e. in the absence of any quantitative theoretical rule), more recently some explicit mathematical models have been described. The performance of these models is now being evaluated on the basis of the real-world experiences conducted in some European countries, especially Italy.

The use of phase sequence image sets to reconstruct the total volume occupied by a mobile lung tumor

International Nuclear Information System (INIS)

Gagne, Isabelle M.; Robinson, Don M.; Halperin, Ross; Roa, Wilson

2005-01-01

The use of phase sequence image (PSI) sets to reveal the total volume occupied by a mobile target is presented. Isocontrast composite clinical target volumes (CCTVs) may be constructed from PSI sets in order to reveal the total volume occupied by a mobile target during the course of its travel. The ability of the CCTV technique to properly account for target motion is demonstrated by comparison to contours of the true total volume occupied (TVO) for a number of experimental phantom geometries. Finally, using real patient data, the clinical utility of the CCTV technique to properly account for internal tumor motion while minimizing the volume of healthy lung tissue irradiated is assessed by comparison to the standard approach of applying safety margins. Results of the phantom study reveal that CCTV cross sections constructed at the 20% isocontrast level yield good agreement with the total cross sections (TXO) of mobile targets. These CCTVs conform well to the TVOs of the moving targets examined whereby the addition of small uniform margins ensures complete circumscription of the TVO with the inclusion of minimal amounts of surrounding external volumes. The CCTV technique is seen to be clearly superior to the common practice of the addition of safety margins to individual CTV contours in order to account for internal target motion. Margins required with the CCTV technique are eight to ten times smaller than those required with individual CTVs

Regional cerebellar volume and cognitive function from adolescence to late middle age.

Science.gov (United States)

Bernard, Jessica A; Leopold, Daniel R; Calhoun, Vince D; Mittal, Vijay A

2015-03-01

Cerebellar morphology and function have been implicated in a variety of developmental disorders, and in healthy aging. Although recent work has sought to characterize the relationships between volume and age in this structure during adolescence, young, and older adulthood, there have been no investigations of regional cerebellar volume from adolescence through late middle age. Middle age in particular has been largely understudied, and investigating this period of the lifespan may be especially important for our understanding of senescence. Understanding regional patterns of cerebellar volume with respect to age during this portion of the lifespan may provide important insight into healthy aging and cognitive function as well as pathology from adolescence into later life. We investigated regional cerebellar volume using a highly novel lobular segmentation approach in conjunction with a battery of cognitive tasks in a cross-sectional sample of 123 individuals from 12 to 65 years old. Our results indicated that regional cerebellar volumes show different patterns with respect to age. In particular, the more posterior aspect of the neocerebellum follows a quadratic "inverse-U" pattern while the vermis and anterior cerebellum follow logarithmic patterns. In addition, we quantified the relationships between age and a variety of cognitive assessments and found relationships between regional cerebellar volumes and performance. Finally, exploratory analyses of sex differences in the relationships between regional cerebellar volume, age, and cognition were investigated. Taken together, these results provide key insights into the development and aging of the human cerebellum, and its role in cognitive function across the lifespan. © 2014 Wiley Periodicals, Inc.

Microstructure-Aided Digital Volume Correlation

Directory of Open Access Journals (Sweden)

Hild F.

2010-06-01

Full Text Available This paper describes how volumic images of a composite material could be used to measure 3D displacement fields, and assess mechanical properties. The exemple of a tensile test performed on a sample made of an energetic material is chosen. Different tools are used, namely, X-ray microtomography of an in situ experiment, image acquisition and processing, volume correlation to measure 3D displacement fields. The principle of an integrated approach is finally introduced.

MR-based automatic delineation of volumes of interest in human brain PET images using probability maps

DEFF Research Database (Denmark)

Svarer, Claus; Madsen, Karina; Hasselbalch, Steen G.

2005-01-01

The purpose of this study was to develop and validate an observer-independent approach for automatic generation of volume-of-interest (VOI) brain templates to be used in emission tomography studies of the brain. The method utilizes a VOI probability map created on the basis of a database of several...... delineation of the VOI set. The approach was also shown to work equally well in individuals with pronounced cerebral atrophy. Probability-map-based automatic delineation of VOIs is a fast, objective, reproducible, and safe way to assess regional brain values from PET or SPECT scans. In addition, the method...

CONTAMINATED SOIL VOLUME ESTIMATE TRACKING METHODOLOGY

International Nuclear Information System (INIS)

Durham, L.A.; Johnson, R.L.; Rieman, C.; Kenna, T.; Pilon, R.

2003-01-01

The U.S. Army Corps of Engineers (USACE) is conducting a cleanup of radiologically contaminated properties under the Formerly Utilized Sites Remedial Action Program (FUSRAP). The largest cost element for most of the FUSRAP sites is the transportation and disposal of contaminated soil. Project managers and engineers need an estimate of the volume of contaminated soil to determine project costs and schedule. Once excavation activities begin and additional remedial action data are collected, the actual quantity of contaminated soil often deviates from the original estimate, resulting in cost and schedule impacts to the project. The project costs and schedule need to be frequently updated by tracking the actual quantities of excavated soil and contaminated soil remaining during the life of a remedial action project. A soil volume estimate tracking methodology was developed to provide a mechanism for project managers and engineers to create better project controls of costs and schedule. For the FUSRAP Linde site, an estimate of the initial volume of in situ soil above the specified cleanup guidelines was calculated on the basis of discrete soil sample data and other relevant data using indicator geostatistical techniques combined with Bayesian analysis. During the remedial action, updated volume estimates of remaining in situ soils requiring excavation were calculated on a periodic basis. In addition to taking into account the volume of soil that had been excavated, the updated volume estimates incorporated both new gamma walkover surveys and discrete sample data collected as part of the remedial action. A civil survey company provided periodic estimates of actual in situ excavated soil volumes. By using the results from the civil survey of actual in situ volumes excavated and the updated estimate of the remaining volume of contaminated soil requiring excavation, the USACE Buffalo District was able to forecast and update project costs and schedule. The soil volume

Optimization of Biodiesel-Diesel Blended Fuel Properties and Engine Performance with Ether Additive Using Statistical Analysis and Response Surface Methods

Directory of Open Access Journals (Sweden)

Obed M. Ali

2015-12-01

Full Text Available In this study, the fuel properties and engine performance of blended palm biodiesel-diesel using diethyl ether as additive have been investigated. The properties of B30 blended palm biodiesel-diesel fuel were measured and analyzed statistically with the addition of 2%, 4%, 6% and 8% (by volume diethyl ether additive. The engine tests were conducted at increasing engine speeds from 1500 rpm to 3500 rpm and under constant load. Optimization of independent variables was performed using the desirability approach of the response surface methodology (RSM with the goal of minimizing emissions and maximizing performance parameters. The experiments were designed using a statistical tool known as design of experiments (DoE based on RSM.

Lung volume reduction for emphysema.

Science.gov (United States)

Shah, Pallav L; Herth, Felix J; van Geffen, Wouter H; Deslee, Gaetan; Slebos, Dirk-Jan

2017-02-01

Advanced emphysema is a lung disease in which alveolar capillary units are destroyed and supporting tissue is lost. The combined effect of reduced gas exchange and changes in airway dynamics impairs expiratory airflow and leads to progressive air trapping. Pharmacological therapies have limited effects. Surgical resection of the most destroyed sections of the lung can improve pulmonary function and exercise capacity but its benefit is tempered by significant morbidity. This issue stimulated a search for novel approaches to lung volume reduction. Alternative minimally invasive approaches using bronchoscopic techniques including valves, coils, vapour thermal ablation, and sclerosant agents have been at the forefront of these developments. Insertion of endobronchial valves in selected patients could have benefits that are comparable with lung volume reduction surgery. Endobronchial coils might have a role in the treatment of patients with emphysema with severe hyperinflation and less parenchymal destruction. Use of vapour thermal energy or a sclerosant might allow focal treatment but the unpredictability of the inflammatory response limits their current use. In this Review, we aim to summarise clinical trial evidence on lung volume reduction and provide guidance on patient selection for available therapies. Copyright © 2017 Elsevier Ltd. All rights reserved.

Force estimation from OCT volumes using 3D CNNs.

Science.gov (United States)

Gessert, Nils; Beringhoff, Jens; Otte, Christoph; Schlaefer, Alexander

2018-05-04

Estimating the interaction forces of instruments and tissue is of interest, particularly to provide haptic feedback during robot-assisted minimally invasive interventions. Different approaches based on external and integrated force sensors have been proposed. These are hampered by friction, sensor size, and sterilizability. We investigate a novel approach to estimate the force vector directly from optical coherence tomography image volumes. We introduce a novel Siamese 3D CNN architecture. The network takes an undeformed reference volume and a deformed sample volume as an input and outputs the three components of the force vector. We employ a deep residual architecture with bottlenecks for increased efficiency. We compare the Siamese approach to methods using difference volumes and two-dimensional projections. Data were generated using a robotic setup to obtain ground-truth force vectors for silicon tissue phantoms as well as porcine tissue. Our method achieves a mean average error of [Formula: see text] when estimating the force vector. Our novel Siamese 3D CNN architecture outperforms single-path methods that achieve a mean average error of [Formula: see text]. Moreover, the use of volume data leads to significantly higher performance compared to processing only surface information which achieves a mean average error of [Formula: see text]. Based on the tissue dataset, our methods shows good generalization in between different subjects. We propose a novel image-based force estimation method using optical coherence tomography. We illustrate that capturing the deformation of subsurface structures substantially improves force estimation. Our approach can provide accurate force estimates in surgical setups when using intraoperative optical coherence tomography.

Wider application of additions in self-compacting concrete

OpenAIRE

Liu, M.

2009-01-01

Compared to normally vibrated concrete (NVC), self-compacting concrete (SCC) possesses enhanced qualities and improves productivity and working conditions due to the elimination of compaction. SCC generally has a higher powder content than NVC and thus it is necessary to replace some of the cement by additions to achieve an economical and durable concrete. The established benefits of using low volumes of fly ash in SCC, high volumes of fly ash in NVC and the search for uses ...

Thermoeconomic analysis of storage systems for solar heating and cooling systems: A comparison between variable-volume and fixed-volume tanks

International Nuclear Information System (INIS)

Buonomano, Annamaria; Calise, Francesco; Ferruzzi, Gabriele

2013-01-01

The paper investigates different control strategies for the thermal storage management in SHC (Solar Heating and Cooling) systems. The SHC system under investigation is based on a field of evacuated solar collectors coupled with a single-stage LiBr–H 2 O absorption chiller; auxiliary thermal energy is supplied by a gas-fired boiler. The SHC is also equipped with a novel thermal storage system, consisting in a variable volume storage tank. It includes three separate tanks and a number of mixers and diverters managed by novel control strategies, based on combinations of series/parallel charging and discharging approaches. The aim of this component is to vary the thermal storage capacity as a function of the combinations of solar radiation availability and user thermal/cooling energy demands. The system allows one to increase the number of active tanks when the time shift between solar energy and user demand is high. Conversely, when this time shift is low, the number of active tanks is automatically reduced. In addition, when the solar energy in excess cannot be stored in such tanks, a heat exchanger is also used in the solar loop for producing DHW (Domestic Hot Water). The analysis is carried out by means of a zero-dimensional transient simulation model, developed by using the TRNSYS software. In order to assess the operating and capital costs of the systems under analysis, an economic model is also proposed. In addition, in order to determine the set of the synthesis/design variables which maximize the system profitability, a parametric analysis was implemented. The novel variable-volume storage system, in both the proposed configurations, was also compared with a constant-volume storage system from the energy and economic points of view. The results showed that the presented storage system allows one to save up to 20% of the natural gas used by the auxiliary boiler only for very high solar fractions. In all the other cases, marginal savings are achieved by the

Ruminal degradation kinetic of Brachiaria decumbens silages with different nitrogen additives

Directory of Open Access Journals (Sweden)

Odimári Pricila Pires do Prado

2014-02-01

Full Text Available This study aimed to assess levels of nitrogen additive Silogen® pasto on ruminal in vitro degradability gas production in Brachiaria decumbens silages. The nitrogen additive contained bacterial strains (Bacillus subtilis, Lactobacillus curvatus, Lactobacillus plantarum and Pediococcus acidilactici and minimum nitrogen to 360 g/kg. The levels were: 0.0; 1.0; 1.5; 2.0 and 2.5%. In fractionation were calculated total carbohydrates (TC, non-fiber carbohydrates (NFC, soluble and rapidly degradable (A + B1, potentially degradable (B2 and degradable (C. The kinetic parameters of FC and NFC were estimated using the technique of in vitro gas production. Data were subjected to analysis of variance at 5%. The level additive did not influence the TC and fraction A + B1. The levels of nitrogen additive influenced the NFC, fractions B2 and C. For NFC content 2.0% showed the lowest (22.0 %. The lower levels of additive nitrogen (0, 1.0 and 1.5 % had higher fractions of B2 (average 40.2 % and lower values for the fraction C (average 20.0 % . There was no difference in the volume of gas CNF (average 86.73 mL and final volume of gas produced (average 195.79 mL. Was no influence of nitrogen additives for the time of colonization, the lowest time of 3.89 h to 1.0%. The volume of gas of FC was influenced by levels of nitrogen additives with higher values to 0 % from 1.0 %, and 114.74 and 115.09 mL, respectively. Degradation rates of FC and FNC were also affected by the concentrations of nitrogenous additives, which presented higher rates to the levels of 2.0 and 2.5%. It follows that the lower levels of additives to 1.5 % promoted the reduction of the C fraction and increased B2, and greater production of gas volume of the fiber in these silages, showing better nutritional value in these silages.

A novel linear programming approach to fluence map optimization for intensity modulated radiation therapy treatment planning

International Nuclear Information System (INIS)

Romeijn, H Edwin; Ahuja, Ravindra K; Dempsey, James F; Kumar, Arvind; Li, Jonathan G

2003-01-01

We present a novel linear programming (LP) based approach for efficiently solving the intensity modulated radiation therapy (IMRT) fluence-map optimization (FMO) problem to global optimality. Our model overcomes the apparent limitations of a linear-programming approach by approximating any convex objective function by a piecewise linear convex function. This approach allows us to retain the flexibility offered by general convex objective functions, while allowing us to formulate the FMO problem as a LP problem. In addition, a novel type of partial-volume constraint that bounds the tail averages of the differential dose-volume histograms of structures is imposed while retaining linearity as an alternative approach to improve dose homogeneity in the target volumes, and to attempt to spare as many critical structures as possible. The goal of this work is to develop a very rapid global optimization approach that finds high quality dose distributions. Implementation of this model has demonstrated excellent results. We found globally optimal solutions for eight 7-beam head-and-neck cases in less than 3 min of computational time on a single processor personal computer without the use of partial-volume constraints. Adding such constraints increased the running times by a factor of 2-3, but improved the sparing of critical structures. All cases demonstrated excellent target coverage (>95%), target homogeneity (<10% overdosing and <7% underdosing) and organ sparing using at least one of the two models

A measure theoretic approach to traffic flow optimization on networks

OpenAIRE

Cacace, Simone; Camilli, Fabio; De Maio, Raul; Tosin, Andrea

2018-01-01

We consider a class of optimal control problems for measure-valued nonlinear transport equations describing traffic flow problems on networks. The objective isto minimise/maximise macroscopic quantities, such as traffic volume or average speed,controlling few agents, for example smart traffic lights and automated cars. The measuretheoretic approach allows to study in a same setting local and nonlocal drivers interactionsand to consider the control variables as additional measures interacting ...

Computational approach to Riemann surfaces

CERN Document Server

Klein, Christian

2011-01-01

This volume offers a well-structured overview of existent computational approaches to Riemann surfaces and those currently in development. The authors of the contributions represent the groups providing publically available numerical codes in this field. Thus this volume illustrates which software tools are available and how they can be used in practice. In addition examples for solutions to partial differential equations and in surface theory are presented. The intended audience of this book is twofold. It can be used as a textbook for a graduate course in numerics of Riemann surfaces, in which case the standard undergraduate background, i.e., calculus and linear algebra, is required. In particular, no knowledge of the theory of Riemann surfaces is expected; the necessary background in this theory is contained in the Introduction chapter. At the same time, this book is also intended for specialists in geometry and mathematical physics applying the theory of Riemann surfaces in their research. It is the first...

Planning additional drilling campaign using two-space genetic algorithm: A game theoretical approach

Science.gov (United States)

Kumral, Mustafa; Ozer, Umit

2013-03-01

Grade and tonnage are the most important technical uncertainties in mining ventures because of the use of estimations/simulations, which are mostly generated from drill data. Open pit mines are planned and designed on the basis of the blocks representing the entire orebody. Each block has different estimation/simulation variance reflecting uncertainty to some extent. The estimation/simulation realizations are submitted to mine production scheduling process. However, the use of a block model with varying estimation/simulation variances will lead to serious risk in the scheduling. In the medium of multiple simulations, the dispersion variances of blocks can be thought to regard technical uncertainties. However, the dispersion variance cannot handle uncertainty associated with varying estimation/simulation variances of blocks. This paper proposes an approach that generates the configuration of the best additional drilling campaign to generate more homogenous estimation/simulation variances of blocks. In other words, the objective is to find the best drilling configuration in such a way as to minimize grade uncertainty under budget constraint. Uncertainty measure of the optimization process in this paper is interpolation variance, which considers data locations and grades. The problem is expressed as a minmax problem, which focuses on finding the best worst-case performance i.e., minimizing interpolation variance of the block generating maximum interpolation variance. Since the optimization model requires computing the interpolation variances of blocks being simulated/estimated in each iteration, the problem cannot be solved by standard optimization tools. This motivates to use two-space genetic algorithm (GA) approach to solve the problem. The technique has two spaces: feasible drill hole configuration with minimization of interpolation variance and drill hole simulations with maximization of interpolation variance. Two-space interacts to find a minmax solution

Understanding the heterogeneity in volume overload and fluid distribution in decompensated heart failure is key to optimal volume management: role for blood volume quantitation.

Science.gov (United States)

Miller, Wayne L; Mullan, Brian P

2014-06-01

This study sought to quantitate total blood volume (TBV) in patients hospitalized for decompensated chronic heart failure (DCHF) and to determine the extent of volume overload, and the magnitude and distribution of blood volume and body water changes following diuretic therapy. The accurate assessment and management of volume overload in patients with DCHF remains problematic. TBV was measured by a radiolabeled-albumin dilution technique with intravascular volume, pre-to-post-diuretic therapy, evaluated at hospital admission and at discharge. Change in body weight in relation to quantitated TBV was used to determine interstitial volume contribution to total fluid loss. Twenty-six patients were prospectively evaluated. Two patients had normal TBV at admission. Twenty-four patients were hypervolemic with TBV (7.4 ± 1.6 liters) increased by +39 ± 22% (range, +9.5% to +107%) above the expected normal volume. With diuresis, TBV decreased marginally (+30 ± 16%). Body weight declined by 6.9 ± 5.2 kg, and fluid intake/fluid output was a net negative 8.4 ± 5.2 liters. Interstitial compartment fluid loss was calculated at 6.2 ± 4.0 liters, accounting for 85 ± 15% of the total fluid reduction. TBV analysis demonstrated a wide range in the extent of intravascular overload. Dismissal measurements revealed marginally reduced intravascular volume post-diuretic therapy despite large reductions in body weight. Mobilization of interstitial fluid to the intravascular compartment with diuresis accounted for this disparity. Intravascular volume, however, remained increased at dismissal. The extent, composition, and distribution of volume overload are highly variable in DCHF, and this variability needs to be taken into account in the approach to individualized therapy. TBV quantitation, particularly serial measurements, can facilitate informed volume management with respect to a goal of treating to euvolemia. Copyright © 2014 American College of Cardiology Foundation. Published

On the Use of Generalized Volume Scattering Models for the Improvement of General Polarimetric Model-Based Decomposition

Directory of Open Access Journals (Sweden)

Qinghua Xie

2017-01-01

Full Text Available Recently, a general polarimetric model-based decomposition framework was proposed by Chen et al., which addresses several well-known limitations in previous decomposition methods and implements a simultaneous full-parameter inversion by using complete polarimetric information. However, it only employs four typical models to characterize the volume scattering component, which limits the parameter inversion performance. To overcome this issue, this paper presents two general polarimetric model-based decomposition methods by incorporating the generalized volume scattering model (GVSM or simplified adaptive volume scattering model, (SAVSM proposed by Antropov et al. and Huang et al., respectively, into the general decomposition framework proposed by Chen et al. By doing so, the final volume coherency matrix structure is selected from a wide range of volume scattering models within a continuous interval according to the data itself without adding unknowns. Moreover, the new approaches rely on one nonlinear optimization stage instead of four as in the previous method proposed by Chen et al. In addition, the parameter inversion procedure adopts the modified algorithm proposed by Xie et al. which leads to higher accuracy and more physically reliable output parameters. A number of Monte Carlo simulations of polarimetric synthetic aperture radar (PolSAR data are carried out and show that the proposed method with GVSM yields an overall improvement in the final accuracy of estimated parameters and outperforms both the version using SAVSM and the original approach. In addition, C-band Radarsat-2 and L-band AIRSAR fully polarimetric images over the San Francisco region are also used for testing purposes. A detailed comparison and analysis of decomposition results over different land-cover types are conducted. According to this study, the use of general decomposition models leads to a more accurate quantitative retrieval of target parameters. However, there

An additive approach to low temperature zero pressure sintering of bismuth antimony telluride thermoelectric materials

Science.gov (United States)

Catlin, Glenn C.; Tripathi, Rajesh; Nunes, Geoffrey; Lynch, Philip B.; Jones, Howard D.; Schmitt, Devin C.

2017-03-01

This paper presents an additive-based approach to the formulation of thermoelectric materials suitable for screen printing. Such printing processes are a likely route to such thermoelectric applications as micro-generators for wireless sensor networks and medical devices, but require the development of materials that can be sintered at ambient pressure and low temperatures. Using a rapid screening process, we identify the eutectic combination of antimony and tellurium as an additive for bismuth-antimony-telluride that enables good thermoelectric performance without a high pressure step. An optimized composite of 15 weight percent Sb7.5Te92.5 in Bi0.5Sb1.5Te3 is scaled up and formulated into a screen-printable paste. Samples fabricated from this paste achieve a thermoelectric figure of merit (ZT) of 0.74 using a maximum processing temperature of 748 K and a total thermal processing budget of 12 K-hours.

Do new anesthesia ventilators deliver small tidal volumes accurately during volume-controlled ventilation?

Science.gov (United States)

Bachiller, Patricia R; McDonough, Joseph M; Feldman, Jeffrey M

2008-05-01

During mechanical ventilation of infants and neonates, small changes in tidal volume may lead to hypo- or hyperventilation, barotrauma, or volutrauma. Partly because breathing circuit compliance and fresh gas flow affect tidal volume delivery by traditional anesthesia ventilators in volume-controlled ventilation (VCV) mode, pressure-controlled ventilation (PCV) using a circle breathing system has become a common approach to minimizing the risk of mechanical ventilation for small patients, although delivered tidal volume is not assured during PCV. A new generation of anesthesia machine ventilators addresses the problems of VCV by adjusting for fresh gas flow and for the compliance of the breathing circuit. In this study, we evaluated the accuracy of new anesthesia ventilators to deliver small tidal volumes. Four anesthesia ventilator systems were evaluated to determine the accuracy of volume delivery to the airway during VCV at tidal volume settings of 100, 200, and 500 mL under different conditions of breathing circuit compliance (fully extended and fully contracted circuits) and lung compliance. A mechanical test lung (adult and infant) was used to simulate lung compliances ranging from 0.0025 to 0.03 L/cm H(2)O. Volumes and pressures were measured using a calibrated screen pneumotachograph and custom software. We tested the Smartvent 7900, Avance, and Aisys anesthesia ventilator systems (GE Healthcare, Madison, WI) and the Apollo anesthesia ventilator (Draeger Medical, Telford, PA). The Smartvent 7900 and Avance ventilators use inspiratory flow sensors to control the volume delivered, whereas the Aisys and Apollo ventilators compensate for the compliance of the circuit. We found that the anesthesia ventilators that use compliance compensation (Aisys and Apollo) accurately delivered both large and small tidal volumes to the airway of the test lung under conditions of normal and low lung compliance during VCV (ranging from 95.5% to 106.2% of the set tidal volume

SCALE-4 analysis of pressurized water reactor critical configurations. Volume 1: Summary

International Nuclear Information System (INIS)

DeHart, M.D.

1995-03-01

The requirements of ANSI/ANS 8.1 specify that calculational methods for away-from-reactor criticality safety analyses be validated against experimental measurements. If credit is to be taken for the reduced reactivity of burned or spent fuel relative to its original fresh composition, it is necessary to benchmark computational methods used in determining such reactivity worth against spent fuel reactivity measurements. This report summarizes a portion of the ongoing effort to benchmark away-from-reactor criticality analysis methods using critical configurations from commercial pressurized water reactors (PWR). The analysis methodology utilized for all calculations in this report is based on the modules and data associated with the SCALE-4 code system. Each of the five volumes comprising this report provides an overview of the methodology applied. Subsequent volumes also describe in detail the approach taken in performing criticality calculations for these PWR configurations: Volume 2 describes criticality calculations for the Tennessee Valley Authority's Sequoyah Unit 2 reactor for Cycle 3; Volume 3 documents the analysis of Virginia Power's Surry Unit 1 reactor for the Cycle 2 core; Volume 4 documents the calculations performed based on GPU Nuclear Corporation's Three Mile Island Unit 1 Cycle 5 core; and, lastly, Volume 5 describes the analysis of Virginia Power's North Anna Unit 1 Cycle 5 core. Each of the reactor-specific volumes provides the details of calculations performed to determine the effective multiplication factor for each reactor core for one or more critical configurations using the SCALE-4 system; these results are summarized in this volume. Differences between the core designs and their possible impact on the criticality calculations are also discussed. Finally, results are presented for additional analyses performed to verify that solutions were sufficiently converged

Individual Global Navigation Satellite Systems in the Space Service Volume

Science.gov (United States)

Force, Dale A.

2015-01-01

Besides providing position, navigation, and timing (PNT) to terrestrial users, GPS is currently used to provide for precision orbit determination, precise time synchronization, real-time spacecraft navigation, and three-axis control of Earth orbiting satellites. With additional Global Navigation Satellite Systems (GNSS) coming into service (GLONASS, Beidou, and Galileo), it will be possible to provide these services by using other GNSS constellations. The paper, "GPS in the Space Service Volume," presented at the ION GNSS 19th International Technical Meeting in 2006 (Ref. 1), defined the Space Service Volume, and analyzed the performance of GPS out to 70,000 km. This paper will report a similar analysis of the performance of each of the additional GNSS and compare them with GPS alone. The Space Service Volume, defined as the volume between 3,000 km altitude and geosynchronous altitude, as compared with the Terrestrial Service Volume between the surface and 3,000 km. In the Terrestrial Service Volume, GNSS performance will be similar to performance on the Earth's surface. The GPS system has established signal requirements for the Space Service Volume. A separate paper presented at the conference covers the use of multiple GNSS in the Space Service Volume.

Demand modelling of passenger air travel: An analysis and extension, volume 2

Science.gov (United States)

Jacobson, I. D.

1978-01-01

Previous intercity travel demand models in terms of their ability to predict air travel in a useful way and the need for disaggregation in the approach to demand modelling are evaluated. The viability of incorporating non-conventional factors (i.e. non-econometric, such as time and cost) in travel demand forecasting models are determined. The investigation of existing models is carried out in order to provide insight into their strong points and shortcomings. The model is characterized as a market segmentation model. This is a consequence of the strengths of disaggregation and its natural evolution to a usable aggregate formulation. The need for this approach both pedagogically and mathematically is discussed. In addition this volume contains two appendices which should prove useful to the non-specialist in the area.

Accurate measurement of volume and shape of resting and activated blood platelets from light scattering.

Science.gov (United States)

Moskalensky, Alexander E; Yurkin, Maxim A; Konokhova, Anastasiya I; Strokotov, Dmitry I; Nekrasov, Vyacheslav M; Chernyshev, Andrei V; Tsvetovskaya, Galina A; Chikova, Elena D; Maltsev, Valeri P

2013-01-01

We introduce a novel approach for determination of volume and shape of individual blood platelets modeled as an oblate spheroid from angle-resolved light scattering with flow-cytometric technique. The light-scattering profiles (LSPs) of individual platelets were measured with the scanning flow cytometer and the platelet characteristics were determined from the solution of the inverse light-scattering problem using the precomputed database of theoretical LSPs. We revealed a phenomenon of parameter compensation, which is partly explained in the framework of anomalous diffraction approximation. To overcome this problem, additional a priori information on the platelet refractive index was used. It allowed us to determine the size of each platelet with subdiffraction precision and independent of the particular value of the platelet aspect ratio. The shape (spheroidal aspect ratio) distributions of platelets showed substantial differences between native and activated by 10 μM adenosine diphosphate samples. We expect that the new approach may find use in hematological analyzers for accurate measurement of platelet volume distribution and for determination of the platelet activation efficiency.

Efficient approach for determining four-dimensional computed tomography-based internal target volume in stereotactic radiotherapy of lung cancer

International Nuclear Information System (INIS)

Yeo, Seung Gu; Kim, Eun Seog

2013-01-01

This study aimed to investigate efficient approaches for determining internal target volume (ITV) from four-dimensional computed tomography (4D CT) images used in stereotactic body radiotherapy (SBRT) for patients with early-stage non-small cell lung cancer (NSCLC). 4D CT images were analyzed for 15 patients who received SBRT for stage I NSCLC. Three different ITVs were determined as follows: combining clinical target volume (CTV) from all 10 respiratory phases (ITV 10Phases ); combining CTV from four respiratory phases, including two extreme phases (0% and 50%) plus two intermediate phases (20% and 70%) (ITV 4Phases ); and combining CTV from two extreme phases (ITV 2Phases ). The matching index (MI) of ITV 4Phases and ITV 2Phases was defined as the ratio of ITV 4Phases and ITV 2Phases , respectively, to the ITV 10Phases . The tumor motion index (TMI) was defined as the ratio of ITV 10Phases to CTV mean , which was the mean of 10 CTVs delineated on 10 respiratory phases. The ITVs were significantly different in the order of ITV 10Phases , ITV 4Phases , and ITV 2Phases (all p 4Phases was significantly higher than that of ITV 2Phases (p 4Phases was inversely related to TMI (r = -0.569, p = 0.034). In a subgroup with low TMI (n = 7), ITV 4Phases was not statistically different from ITV 10Phases (p = 0.192) and its MI was significantly higher than that of ITV 2Phases (p = 0.016). The ITV 4Phases may be an efficient approach alternative to optimal ITV 10Phases in SBRT for early-stage NSCLC with less tumor motion.

Leak testing plan for the Oak Ridge National Laboratory liquid low-level waste systems (active tanks): Revision 2. Volume 1: Regulatory background and plan approach; Volume 2: Methods, protocols, and schedules; Volume 3: Evaluation of the ORNL/LT-823DP differential pressure leak detection method; Appendix to Revision 2: DOE/EPA/TDEC correspondence

Energy Technology Data Exchange (ETDEWEB)

Douglas, D.G.; Wise, R.F.; Starr, J.W.; Maresca, J.W. Jr. [Vista Research, Inc., Mountain View, CA (United States)

1994-11-01

This document, the Leak Testing Plan for the Oak Ridge National Laboratory Liquid Low-Level Waste System (Active Tanks), comprises three volumes. The first two volumes address the component-based leak testing plan for the liquid low-level waste system at Oak Ridge, while the third volume describes the performance evaluation of the leak detection method that will be used to test this system. Volume 1, describes that portion of the liquid low-level waste system at that will be tested; it provides the regulatory background, especially in terms of the requirements stipulated in the Federal Facilities Agreement, upon which the leak testing plan is based. Volume 1 also describes the foundation of the plan, portions of which were abstracted from existing federal documents that regulate the petroleum and hazardous chemicals industries. Finally, Volume 1 gives an overview the plan, describing the methods that will be used to test the four classes of components in the liquid low-level waste system. Volume 2 takes the general information on component classes and leak detection methods presented in Volume 1 and shows how it applies particularly to each of the individual components. A complete test plan for each of the components is presented, with emphasis placed on the methods designated for testing tanks. The protocol for testing tank systems is described, and general leak testing schedules are presented. Volume 3 describes the results of a performance evaluation completed for the leak testing method that will be used to test the small tanks at the facility (those less than 3,000 gal in capacity). Some of the details described in Volumes 1 and 2 are expected to change as additional information is obtained, as the viability of candidate release detection methods is proven in the Oak Ridge environment, and as the testing program evolves.

Leak testing plan for the Oak Ridge National Laboratory liquid low-level waste systems (active tanks): Revision 2. Volume 1: Regulatory background and plan approach; Volume 2: Methods, protocols, and schedules; Volume 3: Evaluation of the ORNL/LT-823DP differential pressure leak detection method; Appendix to Revision 2: DOE/EPA/TDEC correspondence

International Nuclear Information System (INIS)

Douglas, D.G.; Wise, R.F.; Starr, J.W.; Maresca, J.W. Jr.

1994-11-01

This document, the Leak Testing Plan for the Oak Ridge National Laboratory Liquid Low-Level Waste System (Active Tanks), comprises three volumes. The first two volumes address the component-based leak testing plan for the liquid low-level waste system at Oak Ridge, while the third volume describes the performance evaluation of the leak detection method that will be used to test this system. Volume 1, describes that portion of the liquid low-level waste system at that will be tested; it provides the regulatory background, especially in terms of the requirements stipulated in the Federal Facilities Agreement, upon which the leak testing plan is based. Volume 1 also describes the foundation of the plan, portions of which were abstracted from existing federal documents that regulate the petroleum and hazardous chemicals industries. Finally, Volume 1 gives an overview the plan, describing the methods that will be used to test the four classes of components in the liquid low-level waste system. Volume 2 takes the general information on component classes and leak detection methods presented in Volume 1 and shows how it applies particularly to each of the individual components. A complete test plan for each of the components is presented, with emphasis placed on the methods designated for testing tanks. The protocol for testing tank systems is described, and general leak testing schedules are presented. Volume 3 describes the results of a performance evaluation completed for the leak testing method that will be used to test the small tanks at the facility (those less than 3,000 gal in capacity). Some of the details described in Volumes 1 and 2 are expected to change as additional information is obtained, as the viability of candidate release detection methods is proven in the Oak Ridge environment, and as the testing program evolves

State-of-the-Art in GPU-Based Large-Scale Volume Visualization

KAUST Repository

Beyer, Johanna

2015-05-01

This survey gives an overview of the current state of the art in GPU techniques for interactive large-scale volume visualization. Modern techniques in this field have brought about a sea change in how interactive visualization and analysis of giga-, tera- and petabytes of volume data can be enabled on GPUs. In addition to combining the parallel processing power of GPUs with out-of-core methods and data streaming, a major enabler for interactivity is making both the computational and the visualization effort proportional to the amount and resolution of data that is actually visible on screen, i.e. \\'output-sensitive\\' algorithms and system designs. This leads to recent output-sensitive approaches that are \\'ray-guided\\', \\'visualization-driven\\' or \\'display-aware\\'. In this survey, we focus on these characteristics and propose a new categorization of GPU-based large-scale volume visualization techniques based on the notions of actual output-resolution visibility and the current working set of volume bricks-the current subset of data that is minimally required to produce an output image of the desired display resolution. Furthermore, we discuss the differences and similarities of different rendering and data traversal strategies in volume rendering by putting them into a common context-the notion of address translation. For our purposes here, we view parallel (distributed) visualization using clusters as an orthogonal set of techniques that we do not discuss in detail but that can be used in conjunction with what we present in this survey. © 2015 The Eurographics Association and John Wiley & Sons Ltd.

State-of-the-Art in GPU-Based Large-Scale Volume Visualization

KAUST Repository

Beyer, Johanna; Hadwiger, Markus; Pfister, Hanspeter

2015-01-01

This survey gives an overview of the current state of the art in GPU techniques for interactive large-scale volume visualization. Modern techniques in this field have brought about a sea change in how interactive visualization and analysis of giga-, tera- and petabytes of volume data can be enabled on GPUs. In addition to combining the parallel processing power of GPUs with out-of-core methods and data streaming, a major enabler for interactivity is making both the computational and the visualization effort proportional to the amount and resolution of data that is actually visible on screen, i.e. 'output-sensitive' algorithms and system designs. This leads to recent output-sensitive approaches that are 'ray-guided', 'visualization-driven' or 'display-aware'. In this survey, we focus on these characteristics and propose a new categorization of GPU-based large-scale volume visualization techniques based on the notions of actual output-resolution visibility and the current working set of volume bricks-the current subset of data that is minimally required to produce an output image of the desired display resolution. Furthermore, we discuss the differences and similarities of different rendering and data traversal strategies in volume rendering by putting them into a common context-the notion of address translation. For our purposes here, we view parallel (distributed) visualization using clusters as an orthogonal set of techniques that we do not discuss in detail but that can be used in conjunction with what we present in this survey. © 2015 The Eurographics Association and John Wiley & Sons Ltd.

Control volume based hydrocephalus research

Science.gov (United States)

Cohen, Benjamin; Voorhees, Abram; Wei, Timothy

2008-11-01

Hydrocephalus is a disease involving excess amounts of cerebral spinal fluid (CSF) in the brain. Recent research has shown correlations to pulsatility of blood flow through the brain. However, the problem to date has presented as too complex for much more than statistical analysis and understanding. This talk will highlight progress on developing a fundamental control volume approach to studying hydrocephalus. The specific goals are to select physiologically control volume(s), develop conservation equations along with the experimental capabilities to accurately quantify terms in those equations. To this end, an in vitro phantom is used as a simplified model of the human brain. The phantom's design consists of a rigid container filled with a compressible gel. The gel has a hollow spherical cavity representing a ventricle and a cylindrical passage representing the aquaducts. A computer controlled piston pump supplies pulsatile volume fluctuations into and out of the flow phantom. MRI is used to measure fluid velocity, and volume change as functions of time. Independent pressure measurements and flow rate measurements are used to calibrate the MRI data. These data are used as a framework for future work with live patients.

NUMERICAL SIMULATION OF ELECTRICAL IMPEDANCE TOMOGRAPHY PROBLEM AND STUDY OF APPROACH BASED ON FINITE VOLUME METHOD

Directory of Open Access Journals (Sweden)

Ye. S. Sherina

2014-01-01

Full Text Available This research has been aimed to carry out a study of peculiarities that arise in a numerical simulation of the electrical impedance tomography (EIT problem. Static EIT image reconstruction is sensitive to a measurement noise and approximation error. A special consideration has been given to reducing of the approximation error, which originates from numerical implementation drawbacks. This paper presents in detail two numerical approaches for solving EIT forward problem. The finite volume method (FVM on unstructured triangular mesh is introduced. In order to compare this approach, the finite element (FEM based forward solver was implemented, which has gained the most popularity among researchers. The calculated potential distribution with the assumed initial conductivity distribution has been compared to the analytical solution of a test Neumann boundary problem and to the results of problem simulation by means of ANSYS FLUENT commercial software. Two approaches to linearized EIT image reconstruction are discussed. Reconstruction of the conductivity distribution is an ill-posed problem, typically requiring a large amount of computation and resolved by minimization techniques. The objective function to be minimized is constructed of measured voltage and calculated boundary voltage on the electrodes. A classical modified Newton type iterative method and the stochastic differential evolution method are employed. A software package has been developed for the problem under investigation. Numerical tests were conducted on simulated data. The obtained results could be helpful to researches tackling the hardware and software issues for medical applications of EIT.

Mechanical properties of sheet metal components with local reinforcement produced by additive manufacturing

Science.gov (United States)

Ünsal, Ismail; Hama-Saleh, R.; Sviridov, Alexander; Bambach, Markus; Weisheit, A.; Schleifenbaum, J. H.

2018-05-01

New technological challenges like electro-mobility pose an increasing demand for cost-efficient processes for the production of product variants. This demand opens the possibility to combine established die-based manufacturing methods and innovative, dieless technologies like additive manufacturing [1, 2]. In this context, additive manufacturing technologies allow for the weight-efficient local reinforcement of parts before and after forming, enabling manufacturers to produce product variants from series parts [3]. Previous work by the authors shows that the optimal shape of the reinforcing structure can be determined using sizing optimization. Sheet metal parts can then be reinforced using laser metal deposition. The material used is a pearlite-reduced, micro-alloyed steel (ZE 630). The aim of this paper is to determine the effect of the additive manufacturing process on the material behavior and the mechanical properties of the base material and the resulting composite material. The parameters of the AM process are optimized to reach similar material properties in the base material and the build-up volume. A metallographic analysis of the parts is presented, where the additive layers, the base material and also the bonding between the additive layers and the base material are analyzed. The paper shows the feasibility of the approach and details the resulting mechanical properties and performance.

Safety assessment of inter-channel / inter-system digital communications: A defensive measures approach

International Nuclear Information System (INIS)

Thuy, N. N. Q.

2006-01-01

Inappropriately designed inter-channel and inter-system digital communications could initiate common cause failure of multiple channels or multiple systems. Defensive measures were introduced in EPRI report TR-1002835 (Guideline for Performing Defense-in-Depth and Diversity Assessments for Digital Upgrades) to assess, on a deterministic basis, the susceptibility of digital systems architectures to common-cause failures. This paper suggests how this approach could be applied to assess inter-channel and inter-system digital communications from a safety standpoint. The first step of the approach is to systematically identify the so called 'influence factors' that one end of the data communication path can have on the other. Potential factors to be considered would typically include data values, data volumes and data rates. The second step of the approach is to characterize the ways possible failures of a given end of the communication path could affect these influence factors (e.g., incorrect data values, excessive data rates, time-outs, incorrect data volumes). The third step is to analyze the designed-in measures taken to guarantee independence of the other end. In addition to classical error detection and correction codes, typical defensive measures are one-way data communication, fixed-rate data communication, fixed-volume data communication, validation of data values. (authors)

Finite-volume cumulant expansion in QCD-colorless plasma

Energy Technology Data Exchange (ETDEWEB)

Ladrem, M. [Taibah University, Physics Department, Faculty of Science, Al-Madinah, Al-Munawwarah (Saudi Arabia); Physics Department, Algiers (Algeria); ENS-Vieux Kouba (Bachir El-Ibrahimi), Laboratoire de Physique et de Mathematiques Appliquees (LPMA), Algiers (Algeria); Ahmed, M.A.A. [Taibah University, Physics Department, Faculty of Science, Al-Madinah, Al-Munawwarah (Saudi Arabia); ENS-Vieux Kouba (Bachir El-Ibrahimi), Laboratoire de Physique et de Mathematiques Appliquees (LPMA), Algiers (Algeria); Taiz University in Turba, Physics Department, Taiz (Yemen); Alfull, Z.Z. [Taibah University, Physics Department, Faculty of Science, Al-Madinah, Al-Munawwarah (Saudi Arabia); Cherif, S. [ENS-Vieux Kouba (Bachir El-Ibrahimi), Laboratoire de Physique et de Mathematiques Appliquees (LPMA), Algiers (Algeria); Ghardaia University, Sciences and Technologies Department, Ghardaia (Algeria)

2015-09-15

Due to the finite-size effects, the localization of the phase transition in finite systems and the determination of its order, become an extremely difficult task, even in the simplest known cases. In order to identify and locate the finite-volume transition point T{sub 0}(V) of the QCD deconfinement phase transition to a colorless QGP, we have developed a new approach using the finite-size cumulant expansion of the order parameter and the L{sub mn}-method. The first six cumulants C{sub 1,2,3,4,5,6} with the corresponding under-normalized ratios (skewness Σ, kurtosis κ, pentosis Π{sub ±}, and hexosis H{sub 1,2,3}) and three unnormalized combinations of them, (O = σ{sup 2}κΣ{sup -1},U = σ{sup -2}Σ{sup -1},N = σ{sup 2}κ) are calculated and studied as functions of (T, V). A new approach, unifying in a clear and consistent way the definitions of cumulant ratios, is proposed.Anumerical FSS analysis of the obtained results has allowed us to locate accurately the finite-volume transition point. The extracted transition temperature value T{sub 0}(V) agrees with that expected T{sub 0}{sup N}(V) from the order parameter and the thermal susceptibility χ{sub T} (T, V), according to the standard procedure of localization to within about 2%. In addition to this, a very good correlation factor is obtained proving the validity of our cumulants method. The agreement of our results with those obtained by means of other models is remarkable. (orig.)

Scan-based volume animation driven by locally adaptive articulated registrations.

Science.gov (United States)

Rhee, Taehyun; Lewis, J P; Neumann, Ulrich; Nayak, Krishna S

2011-03-01

This paper describes a complete system to create anatomically accurate example-based volume deformation and animation of articulated body regions, starting from multiple in vivo volume scans of a specific individual. In order to solve the correspondence problem across volume scans, a template volume is registered to each sample. The wide range of pose variations is first approximated by volume blend deformation (VBD), providing proper initialization of the articulated subject in different poses. A novel registration method is presented to efficiently reduce the computation cost while avoiding strong local minima inherent in complex articulated body volume registration. The algorithm highly constrains the degrees of freedom and search space involved in the nonlinear optimization, using hierarchical volume structures and locally constrained deformation based on the biharmonic clamped spline. Our registration step establishes a correspondence across scans, allowing a data-driven deformation approach in the volume domain. The results provide an occlusion-free person-specific 3D human body model, asymptotically accurate inner tissue deformations, and realistic volume animation of articulated movements driven by standard joint control estimated from the actual skeleton. Our approach also addresses the practical issues arising in using scans from living subjects. The robustness of our algorithms is tested by their applications on the hand, probably the most complex articulated region in the body, and the knee, a frequent subject area for medical imaging due to injuries. © 2011 IEEE

Viability Assessment Volume 1

International Nuclear Information System (INIS)

1998-01-01

Since May 1996, under its draft Civilian Radioactive Waste Management Program Plan (DOE 1996), DOE has been carrying out a 5-year program of work to support the decision in 2001 by the Secretary of Energy on whether or not to recommend the site to the President. Part of this program was to address major unresolved technical issues and to complete an assessment of the viability of the Yucca Mountain site by 1998. Affirming the DOE plans, Congress directed DOE in the 1997 Energy and Water Development Appropriations Act to provide a viability assessment of the Yucca Mountain site to Congress and the President. This Viability Assessment (VA) document is the DOE report to Congress and the President. They are expected to use the VA to make an informed decision about program direction and funding. Drawing on 15 years of scientific investigation and design work at Yucca Mountain, the VA summarizes a large technical basis of field investigations, laboratory tests, models, analyses, and engineering, described in cited references. The VA identifies the major uncertainties relevant to the technical defensibility of DOE analyses and designs, the DOE approach to managing these uncertainties, and the status of work toward the site recommendation and LA. The VA also identifies DOE plans for the remaining work, and the estimated costs of completing an LA and constructing and operating a repository. The attention to uncertainties is important because DOE must evaluate how the repository will perform during the next 10,000 years or longer. Uncertainties exist because of variability in the natural (geologic and hydrologic) systems at Yucca Mountain and because of imperfect scientific understanding of the natural processes that might affect the repository system. This is Volume 1 and it covers, Introduction and Site Characteristics, includes a high-level summary of the results of the VA and some additional background information. (The overview is bound separately.) Section 1 of Volume

A cache-friendly sampling strategy for texture-based volume rendering on GPU

Directory of Open Access Journals (Sweden)

Junpeng Wang

2017-06-01

Full Text Available The texture-based volume rendering is a memory-intensive algorithm. Its performance relies heavily on the performance of the texture cache. However, most existing texture-based volume rendering methods blindly map computational resources to texture memory and result in incoherent memory access patterns, causing low cache hit rates in certain cases. The distance between samples taken by threads of an atomic scheduling unit (e.g. a warp of 32 threads in CUDA of the GPU is a crucial factor that affects the texture cache performance. Based on this fact, we present a new sampling strategy, called Warp Marching, for the ray-casting algorithm of texture-based volume rendering. The effects of different sample organizations and different thread-pixel mappings in the ray-casting algorithm are thoroughly analyzed. Also, a pipeline manner color blending approach is introduced and the power of warp-level GPU operations is leveraged to improve the efficiency of parallel executions on the GPU. In addition, the rendering performance of the Warp Marching is view-independent, and it outperforms existing empty space skipping techniques in scenarios that need to render large dynamic volumes in a low resolution image. Through a series of micro-benchmarking and real-life data experiments, we rigorously analyze our sampling strategies and demonstrate significant performance enhancements over existing sampling methods.

Cosmological measure with volume averaging and the vacuum energy problem

Science.gov (United States)

Astashenok, Artyom V.; del Popolo, Antonino

2012-04-01

In this paper, we give a possible solution to the cosmological constant problem. It is shown that the traditional approach, based on volume weighting of probabilities, leads to an incoherent conclusion: the probability that a randomly chosen observer measures Λ = 0 is exactly equal to 1. Using an alternative, volume averaging measure, instead of volume weighting can explain why the cosmological constant is non-zero.

Cosmological measure with volume averaging and the vacuum energy problem

International Nuclear Information System (INIS)

Astashenok, Artyom V; Del Popolo, Antonino

2012-01-01

In this paper, we give a possible solution to the cosmological constant problem. It is shown that the traditional approach, based on volume weighting of probabilities, leads to an incoherent conclusion: the probability that a randomly chosen observer measures Λ = 0 is exactly equal to 1. Using an alternative, volume averaging measure, instead of volume weighting can explain why the cosmological constant is non-zero. (paper)

Residual limb fluid volume change and volume accommodation: Relationships to activity and self-report outcomes in people with trans-tibial amputation.

Science.gov (United States)

Sanders, Joan E; Youngblood, Robert T; Hafner, Brian J; Ciol, Marcia A; Allyn, Katheryn J; Gardner, David; Cagle, John C; Redd, Christian B; Dietrich, Colin R

2018-02-01

Fluctuations in limb volume degrade prosthesis fit and require users to accommodate changes using management strategies, such as donning and doffing prosthetic socks. To examine how activities and self-report outcomes relate to daily changes in residual limb fluid volume and volume accommodation. Standardized, two-part laboratory protocol with an interim observational period. Participants were classified as "accommodators" or "non-accommodators," based on self-report prosthetic sock use. Participants' residual limb fluid volume change was measured using a custom bioimpedance analyzer and a standardized in-laboratory activity protocol. Self-report health outcomes were assessed with the Socket Comfort Score and Prosthesis Evaluation Questionnaire. Activity was monitored while participants left the laboratory for at least 3 h. They then returned to repeat the bioimpedance test protocol. Twenty-nine people were enrolled. Morning-to-afternoon percent limb fluid volume change per hour was not strongly correlated to percent time weight-bearing or to self-report outcomes. As a group, non-accommodators ( n = 15) spent more time with their prosthesis doffed and reported better outcomes than accommodators. Factors other than time weight-bearing may contribute to morning-to-afternoon limb fluid volume changes and reported satisfaction with the prosthesis among trans-tibial prosthesis users. Temporary doffing may be a more effective and satisfying accommodation method than sock addition. Clinical relevance Practitioners should be mindful that daily limb fluid volume change and prosthesis satisfaction are not dictated exclusively by activity. Temporarily doffing the prosthesis may slow daily limb fluid volume loss and should be investigated as an alternative strategy to sock addition.

Identifying Structure-Property Relationships Through DREAM.3D Representative Volume Elements and DAMASK Crystal Plasticity Simulations: An Integrated Computational Materials Engineering Approach

Science.gov (United States)

Diehl, Martin; Groeber, Michael; Haase, Christian; Molodov, Dmitri A.; Roters, Franz; Raabe, Dierk

2017-05-01

Predicting, understanding, and controlling the mechanical behavior is the most important task when designing structural materials. Modern alloy systems—in which multiple deformation mechanisms, phases, and defects are introduced to overcome the inverse strength-ductility relationship—give raise to multiple possibilities for modifying the deformation behavior, rendering traditional, exclusively experimentally-based alloy development workflows inappropriate. For fast and efficient alloy design, it is therefore desirable to predict the mechanical performance of candidate alloys by simulation studies to replace time- and resource-consuming mechanical tests. Simulation tools suitable for this task need to correctly predict the mechanical behavior in dependence of alloy composition, microstructure, texture, phase fractions, and processing history. Here, an integrated computational materials engineering approach based on the open source software packages DREAM.3D and DAMASK (Düsseldorf Advanced Materials Simulation Kit) that enables such virtual material development is presented. More specific, our approach consists of the following three steps: (1) acquire statistical quantities that describe a microstructure, (2) build a representative volume element based on these quantities employing DREAM.3D, and (3) evaluate the representative volume using a predictive crystal plasticity material model provided by DAMASK. Exemplarily, these steps are here conducted for a high-manganese steel.

Snow cover volumes dynamic monitoring during melting season using high topographic accuracy approach for a Lebanese high plateau witness sinkhole

Science.gov (United States)

Abou Chakra, Charbel; Somma, Janine; Elali, Taha; Drapeau, Laurent

2017-04-01

Climate change and its negative impact on water resource is well described. For countries like Lebanon, undergoing major population's rise and already decreasing precipitations issues, effective water resources management is crucial. Their continuous and systematic monitoring overs long period of time is therefore an important activity to investigate drought risk scenarios for the Lebanese territory. Snow cover on Lebanese mountains is the most important water resources reserve. Consequently, systematic observation of snow cover dynamic plays a major role in order to support hydrologic research with accurate data on snow cover volumes over the melting season. For the last 20 years few studies have been conducted for Lebanese snow cover. They were focusing on estimating the snow cover surface using remote sensing and terrestrial measurement without obtaining accurate maps for the sampled locations. Indeed, estimations of both snow cover area and volumes are difficult due to snow accumulation very high variability and Lebanese mountains chains slopes topographic heterogeneity. Therefore, the snow cover relief measurement in its three-dimensional aspect and its Digital Elevation Model computation is essential to estimate snow cover volume. Despite the need to cover the all lebanese territory, we favored experimental terrestrial topographic site approaches due to high resolution satellite imagery cost, its limited accessibility and its acquisition restrictions. It is also most challenging to modelise snow cover at national scale. We therefore, selected a representative witness sinkhole located at Ouyoun el Siman to undertake systematic and continuous observations based on topographic approach using a total station. After four years of continuous observations, we acknowledged the relation between snow melt rate, date of total melting and neighboring springs discharges. Consequently, we are able to forecast, early in the season, dates of total snowmelt and springs low

Eddy damping effect of additional conductors in superconducting levitation systems

Science.gov (United States)

Jiang, Zhao-Fei; Gou, Xiao-Fan

2015-12-01

Passive superconducting levitation systems consisting of a high temperature superconductor (HTSC) and a permanent magnet (PM) have demonstrated several fascinating applications such as the maglev system, flywheel energy storage. Generally, for the HTSC-PM levitation system, the HTSC with higher critical current density Jc can obtain larger magnetic force to make the PM levitate over the HTSC (or suspended below the HTSC), however, the process of the vibration of the levitated PM, provides very limited inherent damping (essentially hysteresis). To improve the dynamic stability of the levitated PM, eddy damping of additional conductors can be considered as the most simple and effective approach. In this article, for the HTSC-PM levitation system with an additional copper damper attached to the HTSC, we numerically and comprehensively investigated the damping coefficient c, damping ratio, Joule heating of the copper damper, and the vibration frequency of the PM as well. Furthermore, we comparatively studied four different arrangements of the copper damper, on the comprehensive analyzed the damping effect, efficiency (defined by c/VCu, in which VCu is the volume of the damper) and Joule heating, and finally presented the most advisable arrangement.

Current Scientific Approaches to Decision Making in Complex Systems: 3. Volume 1. Conference Proceedings. Third Conference, Richmond, Surrey, England, 6-8 August 1978

Science.gov (United States)

1980-01-01

good decisions. What usually prevents him from implementing those rational decisions is either an overstrong conflict, leading to behavioural paralysis...of Prosocial Behaviour in the group situation. It assumes a typology of people, and attempts to show sequentially how people are influenced in their...COVERED CURRENT SCIENTIFIC APPROACHES TO DECISION MAKING IN COMPLEX SYSTEMS: III. Volume I, Conference Proceedings 6. PERFORMING ORG. REPORT NUMBER 7

Automated planning volume definition in soft-tissue sarcoma adjuvant brachytherapy

International Nuclear Information System (INIS)

Lee, Eva K.; Fung, Albert Y.C.; Zaider, Marco; Brooks, J. Paul

2002-01-01

In current practice, the planning volume for adjuvant brachytherapy treatment for soft-tissue sarcoma is either not determined a priori (in this case, seed locations are selected based on isodose curves conforming to a visual estimate of the planning volume), or it is derived via a tedious manual process. In either case, the process is subjective and time consuming, and is highly dependent on the human planner. The focus of the work described herein involves the development of an automated contouring algorithm to outline the planning volume. Such an automatic procedure will save time and provide a consistent and objective method for determining planning volumes. In addition, a definitive representation of the planning volume will allow for sophisticated brachytherapy treatment planning approaches to be applied when designing treatment plans, so as to maximize local tumour control and minimize normal tissue complications. An automated tumour volume contouring algorithm is developed utilizing computational geometry and numerical interpolation techniques in conjunction with an artificial intelligence method. The target volume is defined to be the slab of tissue r cm perpendicularly away from the curvilinear plane defined by the mesh of catheters. We assume that if adjacent catheters are over 2r cm apart, the tissue between the two catheters is part of the tumour bed. Input data consist of the digitized coordinates of the catheter positions in each of several cross-sectional slices of the tumour bed, and the estimated distance r from the catheters to the tumour surface. Mathematically, one can view the planning volume as the volume enclosed within a minimal smoothly-connected surface which contains a set of circles, each circle centred at a given catheter position in a given cross-sectional slice. The algorithm performs local interpolation on consecutive triplets of circles. The effectiveness of the algorithm is evaluated based on its performance on a collection of

Automated planning volume definition in soft-tissue sarcoma adjuvant brachytherapy

Energy Technology Data Exchange (ETDEWEB)

Lee, Eva K. [Department of Radiation Oncology, Emory University School of Medicine, Atlanta, GA (United States); School of Industrial and Systems Engineering, Georgia Institute of Technology, Atlanta, GA (United States); Fung, Albert Y.C.; Zaider, Marco [Department of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, NY (United States); Brooks, J. Paul [School of Industrial and Systems Engineering, Georgia Institute of Technology, Atlanta, GA (United States)

2002-06-07

In current practice, the planning volume for adjuvant brachytherapy treatment for soft-tissue sarcoma is either not determined a priori (in this case, seed locations are selected based on isodose curves conforming to a visual estimate of the planning volume), or it is derived via a tedious manual process. In either case, the process is subjective and time consuming, and is highly dependent on the human planner. The focus of the work described herein involves the development of an automated contouring algorithm to outline the planning volume. Such an automatic procedure will save time and provide a consistent and objective method for determining planning volumes. In addition, a definitive representation of the planning volume will allow for sophisticated brachytherapy treatment planning approaches to be applied when designing treatment plans, so as to maximize local tumour control and minimize normal tissue complications. An automated tumour volume contouring algorithm is developed utilizing computational geometry and numerical interpolation techniques in conjunction with an artificial intelligence method. The target volume is defined to be the slab of tissue r cm perpendicularly away from the curvilinear plane defined by the mesh of catheters. We assume that if adjacent catheters are over 2r cm apart, the tissue between the two catheters is part of the tumour bed. Input data consist of the digitized coordinates of the catheter positions in each of several cross-sectional slices of the tumour bed, and the estimated distance r from the catheters to the tumour surface. Mathematically, one can view the planning volume as the volume enclosed within a minimal smoothly-connected surface which contains a set of circles, each circle centred at a given catheter position in a given cross-sectional slice. The algorithm performs local interpolation on consecutive triplets of circles. The effectiveness of the algorithm is evaluated based on its performance on a collection of

Small-Volume Injections: Evaluation of Volume Administration Deviation From Intended Injection Volumes.

Science.gov (United States)

Muffly, Matthew K; Chen, Michael I; Claure, Rebecca E; Drover, David R; Efron, Bradley; Fitch, William L; Hammer, Gregory B

2017-10-01

In the perioperative period, anesthesiologists and postanesthesia care unit (PACU) nurses routinely prepare and administer small-volume IV injections, yet the accuracy of delivered medication volumes in this setting has not been described. In this ex vivo study, we sought to characterize the degree to which small-volume injections (≤0.5 mL) deviated from the intended injection volumes among a group of pediatric anesthesiologists and pediatric postanesthesia care unit (PACU) nurses. We hypothesized that as the intended injection volumes decreased, the deviation from those intended injection volumes would increase. Ten attending pediatric anesthesiologists and 10 pediatric PACU nurses each performed a series of 10 injections into a simulated patient IV setup. Practitioners used separate 1-mL tuberculin syringes with removable 18-gauge needles (Becton-Dickinson & Company, Franklin Lakes, NJ) to aspirate 5 different volumes (0.025, 0.05, 0.1, 0.25, and 0.5 mL) of 0.25 mM Lucifer Yellow (LY) fluorescent dye constituted in saline (Sigma Aldrich, St. Louis, MO) from a rubber-stoppered vial. Each participant then injected the specified volume of LY fluorescent dye via a 3-way stopcock into IV tubing with free-flowing 0.9% sodium chloride (10 mL/min). The injected volume of LY fluorescent dye and 0.9% sodium chloride then drained into a collection vial for laboratory analysis. Microplate fluorescence wavelength detection (Infinite M1000; Tecan, Mannedorf, Switzerland) was used to measure the fluorescence of the collected fluid. Administered injection volumes were calculated based on the fluorescence of the collected fluid using a calibration curve of known LY volumes and associated fluorescence.To determine whether deviation of the administered volumes from the intended injection volumes increased at lower injection volumes, we compared the proportional injection volume error (loge [administered volume/intended volume]) for each of the 5 injection volumes using a linear

The relationship between brain volumes and intelligence in bipolar disorder.

Science.gov (United States)

Vreeker, Annabel; Abramovic, Lucija; Boks, Marco P M; Verkooijen, Sanne; van Bergen, Annet H; Ophoff, Roel A; Kahn, René S; van Haren, Neeltje E M

2017-12-01

Bipolar disorder type-I (BD-I) patients show a lower Intelligence Quotient (IQ) and smaller brain volumes as compared with healthy controls. Considering that in healthy individuals lower IQ is related to smaller total brain volume, it is of interest to investigate whether IQ deficits in BD-I patients are related to smaller brain volumes and to what extent smaller brain volumes can explain differences between premorbid IQ estimates and IQ after a diagnosis of BD-I. Magnetic resonance imaging brain scans, IQ and premorbid IQ scores were obtained from 195 BDI patients and 160 controls. We studied the relationship of (global, cortical and subcortical) brain volumes with IQ and IQ change. Additionally, we investigated the relationship between childhood trauma, lithium- and antipsychotic use and IQ. Total brain volume and IQ were positively correlated in the entire sample. This correlation did not differ between patients and controls. Although brain volumes mediated the relationship between BD-I and IQ in part, the direct relationship between the diagnosis and IQ remained significant. Childhood trauma and use of lithium and antipsychotic medication did not affect the relationship between brain volumes and IQ. However, current lithium use was related to lower IQ in patients. Our data suggest a similar relationship between brain volume and IQ in BD-I patients and controls. Smaller brain volumes only partially explain IQ deficits in patients. Therefore, our findings indicate that in addition to brain volumes and lithium use other disease factors play a role in IQ deficits in BD-I patients. Copyright © 2017 Elsevier B.V. All rights reserved.

Some aspects of the relation between the volume of prostate carcinoma and its interstitial BT volume

International Nuclear Information System (INIS)

Zivanovic, A; Babic, J; Erak, M.; Dabic, K.; Donat, D.; Kuzmanovic, Z.; Savic, D.

1996-01-01

It is a fact that the volume achieved by the interstitial procedure during the brachy treatment of prostate carcinoma is several times smaller than the one we get in, so called, external beam therapy. Furthermore, interstitial brachytherapy offers the possibility to apply large dose into the small volume. However, both dose and volume are at the same time the factors that limit the therapy and the main technical offenders in case of therapy failure. We tried, through a strong individual approach, to compare the volume obtained mathematically and the volume obtained by planning (TPS). By means of clinical examinations and CT scans we conceived a prostate as half of the volume of ellipsoid under one condition only: the magnification of the prostate has to be a symmetrical one. Finally, we applied the following formula: V prostate=(1(2)) ellipsoid=2.09·a/2·e/2·b where a=(1(2)) of sagittal diameter b=prostate height (from apex to base) c=(1(2)) of transversal diameter Each volume obtained in the this way has been taken into account during the application of interstitial needles which in their own way and in accordance to a routine planning, form an active therapeutic interstitial volume. The obtained data showed differences between these two types of volumes. From the statistical point of view, mathematically obtained volume of CV was 16.6% while interstitial volume was 14.9%. T-test was 3.9. On average, mathematical volume is lower and this balance is a desirable one because it means a smaller possibility for potential positive biopsy as a result of a 'rest' tumour. If on the other hand, positive biopsy is a result of the 'rest' tumour and our interpretation has been a contradictory one, precious time with disappointing results will be lost. At the end we achieved: a) double checked control of the embraced volumes, b) stronger fulcrum for the next step: dose-fraction balance

Additive Manufacturing of Dense Hexagonal Boron Nitride Objects

Energy Technology Data Exchange (ETDEWEB)

Marquez Rossy, Andres E [ORNL; Armstrong, Beth L [ORNL; Elliott, Amy M [ORNL; Lara-Curzio, Edgar [ORNL

2017-05-12

The feasibility of manufacturing hexagonal boron nitride objects via additive manufacturing techniques was investigated. It was demonstrated that it is possible to hot-extrude thermoplastic filaments containing uniformly distributed boron nitride particles with a volume concentration as high as 60% and that these thermoplastic filaments can be used as feedstock for 3D-printing objects using a fused deposition system. Objects 3D-printed by fused deposition were subsequently sintered at high temperature to obtain dense ceramic products. In a parallel study the behavior of hexagonal boron nitride in aqueous solutions was investigated. It was shown that the addition of a cationic dispersant to an azeotrope enabled the formulation of slurries with a volume concentration of boron nitride as high as 33%. Although these slurries exhibited complex rheological behavior, the results from this study are encouraging and provide a pathway for manufacturing hexagonal boron nitride objects via robocasting.

Clinical Application of an Open-Source 3D Volume Rendering Software to Neurosurgical Approaches.

Science.gov (United States)

Fernandes de Oliveira Santos, Bruno; Silva da Costa, Marcos Devanir; Centeno, Ricardo Silva; Cavalheiro, Sergio; Antônio de Paiva Neto, Manoel; Lawton, Michael T; Chaddad-Neto, Feres

2018-02-01

Preoperative recognition of the anatomic individualities of each patient can help to achieve more precise and less invasive approaches. It also may help to anticipate potential complications and intraoperative difficulties. Here we describe the use, accuracy, and precision of a free tool for planning microsurgical approaches using 3-dimensional (3D) reconstructions from magnetic resonance imaging (MRI). We used the 3D volume rendering tool of a free open-source software program for 3D reconstruction of images of surgical sites obtained by MRI volumetric acquisition. We recorded anatomic reference points, such as the sulcus and gyrus, and vascularization patterns for intraoperative localization of lesions. Lesion locations were confirmed during surgery by intraoperative ultrasound and/or electrocorticography and later by postoperative MRI. Between August 2015 and September 2016, a total of 23 surgeries were performed using this technique for 9 low-grade gliomas, 7 high-grade gliomas, 4 cortical dysplasias, and 3 arteriovenous malformations. The technique helped delineate lesions with an overall accuracy of 2.6 ± 1.0 mm. 3D reconstructions were successfully performed in all patients, and images showed sulcus, gyrus, and venous patterns corresponding to the intraoperative images. All lesion areas were confirmed both intraoperatively and at the postoperative evaluation. With the technique described herein, it was possible to successfully perform 3D reconstruction of the cortical surface. This reconstruction tool may serve as an adjunct to neuronavigation systems or may be used alone when such a system is unavailable. Copyright © 2017 Elsevier Inc. All rights reserved.

Non-additive measure and integral

CERN Document Server

Denneberg, Dieter

1994-01-01

Non-Additive Measure and Integral is the first systematic approach to the subject. Much of the additive theory (convergence theorems, Lebesgue spaces, representation theorems) is generalized, at least for submodular measures which are characterized by having a subadditive integral. The theory is of interest for applications to economic decision theory (decisions under risk and uncertainty), to statistics (including belief functions, fuzzy measures) to cooperative game theory, artificial intelligence, insurance, etc. Non-Additive Measure and Integral collects the results of scattered and often isolated approaches to non-additive measures and their integrals which originate in pure mathematics, potential theory, statistics, game theory, economic decision theory and other fields of application. It unifies, simplifies and generalizes known results and supplements the theory with new results, thus providing a sound basis for applications and further research in this growing field of increasing interest. It also co...

Interactive volume exploration of petascale microscopy data streams using a visualization-driven virtual memory approach

KAUST Repository

Hadwiger, Markus; Beyer, Johanna; Jeong, Wonki; Pfister, Hanspeter

2012-01-01

This paper presents the first volume visualization system that scales to petascale volumes imaged as a continuous stream of high-resolution electron microscopy images. Our architecture scales to dense, anisotropic petascale volumes because it: (1) decouples construction of the 3D multi-resolution representation required for visualization from data acquisition, and (2) decouples sample access time during ray-casting from the size of the multi-resolution hierarchy. Our system is designed around a scalable multi-resolution virtual memory architecture that handles missing data naturally, does not pre-compute any 3D multi-resolution representation such as an octree, and can accept a constant stream of 2D image tiles from the microscopes. A novelty of our system design is that it is visualization-driven: we restrict most computations to the visible volume data. Leveraging the virtual memory architecture, missing data are detected during volume ray-casting as cache misses, which are propagated backwards for on-demand out-of-core processing. 3D blocks of volume data are only constructed from 2D microscope image tiles when they have actually been accessed during ray-casting. We extensively evaluate our system design choices with respect to scalability and performance, compare to previous best-of-breed systems, and illustrate the effectiveness of our system for real microscopy data from neuroscience. © 1995-2012 IEEE.

Interactive volume exploration of petascale microscopy data streams using a visualization-driven virtual memory approach

KAUST Repository

Hadwiger, Markus

2012-12-01

This paper presents the first volume visualization system that scales to petascale volumes imaged as a continuous stream of high-resolution electron microscopy images. Our architecture scales to dense, anisotropic petascale volumes because it: (1) decouples construction of the 3D multi-resolution representation required for visualization from data acquisition, and (2) decouples sample access time during ray-casting from the size of the multi-resolution hierarchy. Our system is designed around a scalable multi-resolution virtual memory architecture that handles missing data naturally, does not pre-compute any 3D multi-resolution representation such as an octree, and can accept a constant stream of 2D image tiles from the microscopes. A novelty of our system design is that it is visualization-driven: we restrict most computations to the visible volume data. Leveraging the virtual memory architecture, missing data are detected during volume ray-casting as cache misses, which are propagated backwards for on-demand out-of-core processing. 3D blocks of volume data are only constructed from 2D microscope image tiles when they have actually been accessed during ray-casting. We extensively evaluate our system design choices with respect to scalability and performance, compare to previous best-of-breed systems, and illustrate the effectiveness of our system for real microscopy data from neuroscience. © 1995-2012 IEEE.

Aperiodic Volume Optics

Science.gov (United States)

Gerke, Tim D.

periodic and quasi-periodic systems for the manipulation of light in the IR regime. The general thesis of this document is that aperiodic three-dimensional structures provide additional degrees of freedom that can be utilized to improve on the performance of periodic volume devices. The results we will discuss suggest that, under certain circumstances, a departure from the Bragg paradigm provides enhanced volume diffraction properties.

Dosimetric Advantages of Midventilation Compared With Internal Target Volume for Radiation Therapy of Pancreatic Cancer

Energy Technology Data Exchange (ETDEWEB)

Lens, Eelco, E-mail: e.lens@amc.uva.nl; Horst, Astrid van der; Versteijne, Eva; Tienhoven, Geertjan van; Bel, Arjan

2015-07-01

Purpose: The midventilation (midV) approach can be used to take respiratory-induced pancreatic tumor motion into account during radiation therapy. In this study, the dosimetric consequences for organs at risk and tumor coverage of using a midV approach compared with using an internal target volume (ITV) were investigated. Methods and Materials: For each of the 18 patients, 2 treatment plans (25 × 2.0 Gy) were created, 1 using an ITV and 1 using a midV approach. The midV dose distribution was blurred using the respiratory-induced motion from 4-dimensional computed tomography. The resulting planning target volume (PTV) coverage for this blurred dose distribution was analyzed; PTV coverage was required to be at least V{sub 95%} >98%. In addition, the change in PTV size and the changes in V{sub 10Gy}, V{sub 20Gy}, V{sub 30Gy}, V{sub 40Gy}, D{sub mean} and D{sub 2cc} for the stomach and for the duodenum were analyzed; differences were tested for significance using the Wilcoxon signed-rank test. Results: Using a midV approach resulted in sufficient target coverage. A highly significant PTV size reduction of 13.9% (P<.001) was observed. Also, all dose parameters for the stomach and duodenum, except the D{sub 2cc} of the duodenum, improved significantly (P≤.002). Conclusions: By using the midV approach to account for respiratory-induced tumor motion, a significant PTV reduction and significant dose reductions to the stomach and to the duodenum can be achieved when irradiating pancreatic tumors.

Dosimetric Advantages of Midventilation Compared With Internal Target Volume for Radiation Therapy of Pancreatic Cancer

International Nuclear Information System (INIS)

Lens, Eelco; Horst, Astrid van der; Versteijne, Eva; Tienhoven, Geertjan van; Bel, Arjan

2015-01-01

Purpose: The midventilation (midV) approach can be used to take respiratory-induced pancreatic tumor motion into account during radiation therapy. In this study, the dosimetric consequences for organs at risk and tumor coverage of using a midV approach compared with using an internal target volume (ITV) were investigated. Methods and Materials: For each of the 18 patients, 2 treatment plans (25 × 2.0 Gy) were created, 1 using an ITV and 1 using a midV approach. The midV dose distribution was blurred using the respiratory-induced motion from 4-dimensional computed tomography. The resulting planning target volume (PTV) coverage for this blurred dose distribution was analyzed; PTV coverage was required to be at least V 95% >98%. In addition, the change in PTV size and the changes in V 10Gy , V 20Gy , V 30Gy , V 40Gy , D mean and D 2cc for the stomach and for the duodenum were analyzed; differences were tested for significance using the Wilcoxon signed-rank test. Results: Using a midV approach resulted in sufficient target coverage. A highly significant PTV size reduction of 13.9% (P<.001) was observed. Also, all dose parameters for the stomach and duodenum, except the D 2cc of the duodenum, improved significantly (P≤.002). Conclusions: By using the midV approach to account for respiratory-induced tumor motion, a significant PTV reduction and significant dose reductions to the stomach and to the duodenum can be achieved when irradiating pancreatic tumors

[Target volume margins for lung cancer: internal target volume/clinical target volume].

Science.gov (United States)

Jouin, A; Pourel, N

2013-10-01

The aim of this study was to carry out a review of margins that should be used for the delineation of target volumes in lung cancer, with a focus on margins from gross tumour volume (GTV) to clinical target volume (CTV) and internal target volume (ITV) delineation. Our review was based on a PubMed literature search with, as a cornerstone, the 2010 European Organisation for Research and Treatment of Cancer (EORTC) recommandations by De Ruysscher et al. The keywords used for the search were: radiotherapy, lung cancer, clinical target volume, internal target volume. The relevant information was categorized under the following headings: gross tumour volume definition (GTV), CTV-GTV margin (first tumoural CTV then nodal CTV definition), in field versus elective nodal irradiation, metabolic imaging role through the input of the PET scanner for tumour target volume and limitations of PET-CT imaging for nodal target volume definition, postoperative radiotherapy target volume definition, delineation of target volumes after induction chemotherapy; then the internal target volume is specified as well as tumoural mobility for lung cancer and respiratory gating techniques. Finally, a chapter is dedicated to planning target volume definition and another to small cell lung cancer. For each heading, the most relevant and recent clinical trials and publications are mentioned. Copyright © 2013. Published by Elsevier SAS.

Longitudinal analysis of mouse SDOCT volumes

Science.gov (United States)

Antony, Bhavna J.; Carass, Aaron; Lang, Andrew; Kim, Byung-Jin; Zack, Donald J.; Prince, Jerry L.

2017-03-01

Spectral-domain optical coherence tomography (SDOCT), in addition to its routine clinical use in the diagnosis of ocular diseases, has begun to fund increasing use in animal studies. Animal models are frequently used to study disease mechanisms as well as to test drug efficacy. In particular, SDOCT provides the ability to study animals longitudinally and non-invasively over long periods of time. However, the lack of anatomical landmarks makes the longitudinal scan acquisition prone to inconsistencies in orientation. Here, we propose a method for the automated registration of mouse SDOCT volumes. The method begins by accurately segmenting the blood vessels and the optic nerve head region in the scans using a pixel classification approach. The segmented vessel maps from follow-up scans were registered using an iterative closest point (ICP) algorithm to the baseline scan to allow for the accurate longitudinal tracking of thickness changes. Eighteen SDOCT volumes from a light damage model study were used to train a random forest utilized in the pixel classification step. The area under the curve (AUC) in a leave-one-out study for the retinal blood vessels and the optic nerve head (ONH) was found to be 0.93 and 0.98, respectively. The complete proposed framework, the retinal vasculature segmentation and the ICP registration, was applied to a secondary set of scans obtained from a light damage model. A qualitative assessment of the registration showed no registration failures.

Comparison of three approaches to delineate internal gross tumor volume based on four-dimensional CT simulation images of non-small-cell lung cancer

International Nuclear Information System (INIS)

Li Fengxiang; Li Jianbin; Zhang Yingjie; Shang Dongping; Liu Tonghai; Tian Shiyu; Xu Min; Ma Changsheng

2011-01-01

Objective: To compare positional and volumetric differences of internal gross tumor volume (IGTV) delineated separately by three approaches based on four-dimensional CT (4DCT) for the primary tumor of non-small cell lung cancer (NLCLC). Methods: Twenty-one patients with NLCLC underwent big bore 4DCT simulation scan of the thorax. IGTVs of the primary tumor of NSCLC were delineated using three approaches as followed: (1) the gross tumor volume (GTV) on each of the ten the respiratory phases of the 4DCT image set were delineated and the ten GTV were fused to produce IGTV 10 ; (2) the GTV delineated separately based on 0% and 50% phase were fused to produce IGTV EI+EE ; (3) the visible tumor on the MIP images were delineated to produce IGTV MIP . The position of the target center, the volume of target, the degree of inclusion (DI) and the matching index (MI) were compared reciprocally between IGTV 10 , IGTV EI+EE and IGTV MIP . Results: Average differences between the position of the center of IGTVs on direction of x, y and z axes were less than 1 mm, with no statistically significant difference. The volume of IGTV 10 was larger than that of IGTV EI+EE , the difference was statistically significant (t=2.37, P=0.028); the volume of IGTV 10 was larger than that of IGTV MIP , but the difference was not statistically significant (t=1.95, P=0.065). The ratio of IGTV EI+EE with IGTV 10 , IGTV MIP with IGTV 10 were 0.85±0.08 and 0.92±0.11, respectively. DI of IGTV EI+EE in IGTV 10 , IGTV MIP in IGTV 10 were 84.78% ± 8. 95% and 88.47% ±9.04%. MI between IGTV 10 and IGTV EI+EE , IGTV 10 and IGTV MIP were 0.85 ±0.09, 0.86±0.09, respectively. Conclusions: The center displacement of the IGTVs delineated separately by the three different techniques based on 4DCT images are not obvious; IGTV EI+EE and IGTV MIP can not replace IGTV 10 , however, IGTV MIP is more close to IGTV 10 comparing to IGTV EI+EE . The ratio of GTV EI+EE with IGTV 10 is correlated to the tumor motion

Planimetric determination of lung volume

International Nuclear Information System (INIS)

Bieber, M.; Maurer, H.J.

1984-01-01

The total volume of the lungs was determined by digital planimetry in 102 patients with emphysema and 33 normal controls aged between 30 and 79 years. The results were compared with the findings obtained from spirometric measurements. Mean values showed a significant relationship to age, body size and body surface. Planimetrically determined lung volume did not show a linear relationship with age, but increased after 60 years. Beyong 60 years, spirometric findings were lower because of an increase in the number of patients with emphysema. The results have shown that digital planimetry is a useful addition to spirometry. (orig.) [de

CADDIS Volume 4. Data Analysis: Selecting an Analysis Approach

Science.gov (United States)

An approach for selecting statistical analyses to inform causal analysis. Describes methods for determining whether test site conditions differ from reference expectations. Describes an approach for estimating stressor-response relationships.

Additive Number Theory Festschrift in Honor of the Sixtieth Birthday of Melvyn B Nathanson

CERN Document Server

Chudnovsky, David

2010-01-01

This impressive volume is dedicated to Mel Nathanson, a leading authoritative expert for several decades in the area of combinatorial and additive number theory. For several decades, Mel Nathanson's seminal ideas and results in combinatorial and additive number theory have influenced graduate students and researchers alike. The invited survey articles in this volume reflect the work of distinguished mathematicians in number theory, and represent a wide range of important topics in current research.

Automatic delineation of functional volumes in emission tomography for oncology applications

International Nuclear Information System (INIS)

Hatt, M.

2008-12-01

One of the main factors of error for semi-quantitative analysis in positron emission tomography (PET) imaging for diagnosis and patient follow up, as well as new flourishing applications like image guided radiotherapy, is the methodology used to define the volumes of interest in the functional images. This is explained by poor image quality in emission tomography resulting from noise and partial volume effects induced blurring, as well as the variability of acquisition protocols, scanner models and image reconstruction procedures. The large number of proposed methodologies for the definition of a PET volume of interest does not help either. The majority of such proposed approaches are based on deterministic binary thresholding that are not robust to contrast variation and noise. In addition, these methodologies are usually unable to correctly handle heterogeneous uptake inside tumours. The objective of this thesis is to develop an automatic, robust, accurate and reproducible 3D image segmentation approach for the functional volumes determination of tumours of all sizes and shapes, and whose activity distribution may be strongly heterogeneous. The approach we have developed is based on a statistical image segmentation framework, combined with a fuzzy measure, which allows to take into account both noisy and blurry properties of nuclear medicine images. It uses a stochastic iterative parameters estimation and a locally adaptive model of the voxel and its neighbours for the estimation and segmentation. The developed approaches have been evaluated using a large array of datasets, comprising both simulated and real acquisitions of phantoms and tumours. The results obtained on phantom acquisitions allowed to validate the accuracy of the segmentation with respect to the size of considered structures, down to 13 mm in diameter (about twice the spatial resolution of a typical PET scanner), as well as its robustness with respect to noise, contrast variation, acquisition

Fourier-based approach to interpolation in single-slice helical computed tomography

International Nuclear Information System (INIS)

La Riviere, Patrick J.; Pan Xiaochuan

2001-01-01

It has recently been shown that longitudinal aliasing can be a significant and detrimental presence in reconstructed single-slice helical computed tomography (CT) volumes. This aliasing arises because the directly measured data in helical CT are generally undersampled by a factor of at least 2 in the longitudinal direction and because the exploitation of the redundancy of fanbeam data acquired over 360 degree sign to generate additional longitudinal samples does not automatically eliminate the aliasing. In this paper we demonstrate that for pitches near 1 or lower, the redundant fanbeam data, when used properly, can provide sufficient information to satisfy a generalized sampling theorem and thus to eliminate aliasing. We develop and evaluate a Fourier-based algorithm, called 180FT, that accomplishes this. As background we present a second Fourier-based approach, called 360FT, that makes use only of the directly measured data. Both Fourier-based approaches exploit the fast Fourier transform and the Fourier shift theorem to generate from the helical projection data a set of fanbeam sinograms corresponding to equispaced transverse slices. Slice-by-slice reconstruction is then performed by use of two-dimensional fanbeam algorithms. The proposed approaches are compared to their counterparts based on the use of linear interpolation - the 360LI and 180LI approaches. The aliasing suppression property of the 180FT approach is a clear advantage of the approach and represents a step toward the desirable goal of achieving uniform longitudinal resolution properties in reconstructed helical CT volumes

78 FR 49411 - Denial of Petitions for Reconsideration of Regulation of Fuels and Fuel Additives: 2013 Biomass...

Science.gov (United States)

2013-08-14

...-AR55 Denial of Petitions for Reconsideration of Regulation of Fuels and Fuel Additives: 2013 Biomass... Fuel Additives: 2013 Biomass-Based Diesel Renewable Fuel Volume. DATES: EPA's denials of the petitions... requires that EPA determine the applicable volume of biomass-based diesel to be used in setting annual...

Thermodynamic study of (heptane + amine) mixtures. II. Excess and partial molar volumes at 298.15 K

International Nuclear Information System (INIS)

Lepori, Luciano; Gianni, Paolo; Spanedda, Andrea; Matteoli, Enrico

2011-01-01

Research highlights: → Excess and partial molar volumes of primary (amines + heptane) mixtures. → Excess volumes are positive for small size amines and decrease as the size increases. → Group contributions to predict the partial molar volumes of amines in heptane. → The void volume is larger for branched than for linear amines in heptane. - Abstract: Excess molar volumes V E at 298.15 K were determined by means of a vibrating tube densimeter for binary mixtures of heptane + primary n-alkyl (C 3 to C 10 ) and branched amines (iso-propyl-, iso-, sec-, and tert-butyl-, iso-, tert-pentyl-, and pentan-3-amine) in the whole composition range. The apparent molar volumes of solid dodecyl- and tetradecylamine in heptane dilute solution were also determined. The V E values were found positive for mixtures involving C 3 to C 8 linear amines, with V E decreasing with chain lengthening. Heptane + nonyl and decylamine showed s-shaped, markedly asymmetric, curves. Mixtures with branched C 3 to C 5 amines displayed positive V E 's larger than those observed in the mixtures of the corresponding linear isomers. Partial molar volumes V o at infinite dilution in heptane were evaluated for the examined amines and compared with those of alkanes and alkanols taken from the literature. An additivity scheme, based on the intrinsic volume approach, was applied to estimate group (CH 3 , CH 2 , CH, C, NH 2 , and OH) contributions to V o . The effect of branching on V o and the limiting slope of the apparent excess molar volumes were evaluated and discussed in terms of solute-solvent and solute-solute interactions.

Determination of correlation between backflow volume and mitral valve leaflet young modulus from two dimensional echocardiogram images

Science.gov (United States)

Jong, Rudiyanto P.; Osman, Kahar; Adib, M. Azrul Hisham M.

2012-06-01

Mitral valve prolapse without proper monitoring might lead to a severe mitral valve failure which eventually leads to a sudden death. Additional information on the mitral valve leaflet condition against the backflow volume would be an added advantage to the medical practitioner for their decision on the patients' treatment. A study on two dimensional echocardiography images has been conducted and the correlations between the backflow volume of the mitral regurgitation and mitral valve leaflet Young modulus have been obtained. Echocardiogram images were analyzed on the aspect of backflow volume percentage and mitral valve leaflet dimensions on different rates of backflow volume. Young modulus values for the mitral valve leaflet were obtained by using the principle of elastic deflection and deformation on the mitral valve leaflet. The results show that the backflow volume increased with the decrease of the mitral valve leaflet Young modulus which also indicate the condition of the mitral valve leaflet approaching failure at high backflow volumes. Mitral valve leaflet Young modulus values obtained in this study agreed with the healthy mitral valve leaflet Young modulus from the literature. This is an initial overview of the trend on the prediction of the behaviour between the fluid and the structure of the blood and the mitral valve which is extendable to a larger system of prediction on the mitral valve leaflet condition based on the available echocardiogram images.

Approach to Absolute Zero

Indian Academy of Sciences (India)

Home; Journals; Resonance – Journal of Science Education; Volume 2; Issue 10. Approach to Absolute Zero Below 10 milli-Kelvin. R Srinivasan. Series Article Volume 2 Issue 10 October 1997 pp 8-16. Fulltext. Click here to view fulltext PDF. Permanent link: https://www.ias.ac.in/article/fulltext/reso/002/10/0008-0016 ...

Volumes and doses for external radiotherapy - Definitions and recommendations; Volum og doser i ekstern straaleterapi - Definisjoner og anbefalinger

Energy Technology Data Exchange (ETDEWEB)

Levernes, Sverre (ed.)

2012-07-01

The report contains definitions of volume and dose parameters for external radiotherapy. In addition the report contains recommendations for use, documentation and minimum reporting for radiotherapy of the individual patient.(Author)

A volume of intersection approach for on-the-fly system matrix calculation in 3D PET image reconstruction

International Nuclear Information System (INIS)

Lougovski, A; Hofheinz, F; Maus, J; Schramm, G; Will, E; Hoff, J van den

2014-01-01

The aim of this study is the evaluation of on-the-fly volume of intersection computation for system’s geometry modelling in 3D PET image reconstruction. For this purpose we propose a simple geometrical model in which the cubic image voxels on the given Cartesian grid are approximated with spheres and the rectangular tubes of response (ToRs) are approximated with cylinders. The model was integrated into a fully 3D list-mode PET reconstruction for performance evaluation. In our model the volume of intersection between a voxel and the ToR is only a function of the impact parameter (the distance between voxel centre to ToR axis) but is independent of the relative orientation of voxel and ToR. This substantially reduces the computational complexity of the system matrix calculation. Based on phantom measurements it was determined that adjusting the diameters of the spherical voxel size and the ToR in such a way that the actual voxel and ToR volumes are conserved leads to the best compromise between high spatial resolution, low noise, and suppression of Gibbs artefacts in the reconstructed images. Phantom as well as clinical datasets from two different PET systems (Siemens ECAT HR + and Philips Ingenuity-TF PET/MR) were processed using the developed and the respective vendor-provided (line of intersection related) reconstruction algorithms. A comparison of the reconstructed images demonstrated very good performance of the new approach. The evaluation showed the respective vendor-provided reconstruction algorithms to possess 34–41% lower resolution compared to the developed one while exhibiting comparable noise levels. Contrary to explicit point spread function modelling our model has a simple straight-forward implementation and it should be easy to integrate into existing reconstruction software, making it competitive to other existing resolution recovery techniques. (paper)

Evaluation of droplet size distributions using univariate and multivariate approaches

DEFF Research Database (Denmark)

Gauno, M.H.; Larsen, C.C.; Vilhelmsen, T.

2013-01-01

of the distribution. The current study was aiming to compare univariate and multivariate approach in evaluating droplet size distributions. As a model system, the atomization of a coating solution from a two-fluid nozzle was investigated. The effect of three process parameters (concentration of ethyl cellulose...... in ethanol, atomizing air pressure, and flow rate of coating solution) on the droplet size and droplet size distribution using a full mixed factorial design was used. The droplet size produced by a two-fluid nozzle was measured by laser diffraction and reported as volume based size distribution....... Investigation of loading and score plots from principal component analysis (PCA) revealed additional information on the droplet size distributions and it was possible to identify univariate statistics (volume median droplet size), which were similar, however, originating from varying droplet size distributions...

Interdisciplinary periodontics: the multidisciplinary approach to the planning and treatment of complex cases.

Science.gov (United States)

Lyons, Karl M; Darby, Ivan

2017-06-01

Periodontics cannot be practiced in isolation as frequently many patients have multiple dental needs or medical health issues requiring management. In addition, pathology may manifest in the periodontal tissues, and the onset and progression of periodontitis can be affected by systemic conditions, such as diabetes, and vice versa. The focus of this volume of Periodontology 2000 is interdisciplinary periodontics, and the articles included discuss the interactions and the interrelationshipbetween periodontal tissues/periodontal diseases and endodontics, fixed prosthodontics, implant dentistry, esthetics, gerodontology, radiology, orthodontics, pediatric dentistry, oral and maxillofacial surgery, oral pathology, special needs dentistry and general medicine. Previous volumes of Periodontology 2000 have covered some of the interactions between periodontal diseases and other dental disciplines, especially implant dentistry, 'and the interaction between periodontal disease and systemic disease', but there has not been a volume on interdisciplinary periodontics. The intention therefore is to show how and why periodontics should be interdisciplinary, as well as the benefits of an interdisciplinary approach; in addition, the potential consequences of using a discipline in isolation are discussed. © 2017 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Structural covariance of brain region volumes is associated with both structural connectivity and transcriptomic similarity.

Science.gov (United States)

Yee, Yohan; Fernandes, Darren J; French, Leon; Ellegood, Jacob; Cahill, Lindsay S; Vousden, Dulcie A; Spencer Noakes, Leigh; Scholz, Jan; van Eede, Matthijs C; Nieman, Brian J; Sled, John G; Lerch, Jason P

2018-05-18

An organizational pattern seen in the brain, termed structural covariance, is the statistical association of pairs of brain regions in their anatomical properties. These associations, measured across a population as covariances or correlations usually in cortical thickness or volume, are thought to reflect genetic and environmental underpinnings. Here, we examine the biological basis of structural volume covariance in the mouse brain. We first examined large scale associations between brain region volumes using an atlas-based approach that parcellated the entire mouse brain into 318 regions over which correlations in volume were assessed, for volumes obtained from 153 mouse brain images via high-resolution MRI. We then used a seed-based approach and determined, for 108 different seed regions across the brain and using mouse gene expression and connectivity data from the Allen Institute for Brain Science, the variation in structural covariance data that could be explained by distance to seed, transcriptomic similarity to seed, and connectivity to seed. We found that overall, correlations in structure volumes hierarchically clustered into distinct anatomical systems, similar to findings from other studies and similar to other types of networks in the brain, including structural connectivity and transcriptomic similarity networks. Across seeds, this structural covariance was significantly explained by distance (17% of the variation, up to a maximum of 49% for structural covariance to the visceral area of the cortex), transcriptomic similarity (13% of the variation, up to maximum of 28% for structural covariance to the primary visual area) and connectivity (15% of the variation, up to a maximum of 36% for structural covariance to the intermediate reticular nucleus in the medulla) of covarying structures. Together, distance, connectivity, and transcriptomic similarity explained 37% of structural covariance, up to a maximum of 63% for structural covariance to the

Stereological quantification of tumor volume, mean nuclear volume and total number of melanoma cells correlated with morbidity and mortality

DEFF Research Database (Denmark)

Bønnelykke-Behrndtz, Marie Louise; Sørensen, Flemming Brandt; Damsgaard, Tine Engberg

2008-01-01

potential indicators of prognosis. Sixty patients who underwent surgery at the Department of Plastic Surgery, Aarhus University Hospital, from 1991 to 1994 were included in the study. Total tumor volume was estimated by the Cavalieri technique, total number of tumor cells by the optical dissector principle...... showed a significant impact on both disease-free survival (p=0.001) and mortality (p=0.009). In conclusion, tumor volume and total number of cancer cells were highly reproducible but did not add additional, independent prognostic information regarding the study population.......Stereological quantification of tumor volume, total number of tumor cells and mean nuclear volume provides unbiased data, regardless of the three-dimensional shape of the melanocytic lesion. The aim of the present study was to investigate whether these variables are reproducible and may represent...

Specification of volume and dose in radiotherapy

International Nuclear Information System (INIS)

Levernes, S.

1997-01-01

As a result of a questionnaire about dose and volume specifications in radiotherapy in the Nordic countries, a group has been set up to propose common recommendations for these countries. The proposal is partly based on ICRU 50, but with major extensions. These extensions fall into three areas: patient geometry, treatment geometry, and dose specifications. For patient geometry and set-up one need alignment markings and anatomical reference points, the latter can be divided into internal and external reference points. These points are necessary to get relationships between coordinate systems related to patient and to treatment unit. For treatment geometry the main volume will be an anatomical target volume which just encompass the clinical target volume with all its variations and movements. This anatomical volume are the most suitable volume for prescription, optimization and reporting dose. A set-up margin should be added to the beam periphery in beams-eye-view to get the minimum size and shape of the beam. For dose specification the most important parameter for homogeneous dose distributions is the arithmetic mean of dose to the anatomical target volume together with its standard deviation. In addition the dose to the ICRU reference point should be reported for intercomparison, together with minimum and maximum doses or dose volume histograms for the anatomical target volume. (author)

Development of a partitioned finite volume-finite element fluid-structure interaction scheme for strongly-coupled problems

CSIR Research Space (South Africa)

Suliman, Ridhwaan

2012-07-01

Full Text Available -linear deformations are accounted for. As will be demonstrated, the finite volume approach exhibits similar disad- vantages to the linear Q4 finite element formulation when undergoing bending. An enhanced finite volume approach is discussed and compared with finite...

Quantitative prediction of respiratory tidal volume based on the external torso volume change: a potential volumetric surrogate

International Nuclear Information System (INIS)

Li Guang; Arora, Naveen C; Xie Huchen; Ning, Holly; Citrin, Deborah; Kaushal, Aradhana; Zach, Leor; Camphausen, Kevin; Miller, Robert W; Lu Wei; Low, Daniel

2009-01-01

An external respiratory surrogate that not only highly correlates with but also quantitatively predicts internal tidal volume should be useful in guiding four-dimensional computed tomography (4DCT), as well as 4D radiation therapy (4DRT). A volumetric surrogate should have advantages over external fiducial point(s) for monitoring respiration-induced motion of the torso, which deforms in synchronization with a patient-specific breathing pattern. This study establishes a linear relationship between the external torso volume change (TVC) and lung air volume change (AVC) by validating a proposed volume conservation hypothesis (TVC = AVC) throughout the respiratory cycle using 4DCT and spirometry. Fourteen patients' torso 4DCT images and corresponding spirometric tidal volumes were acquired to examine this hypothesis. The 4DCT images were acquired using dual surrogates in cine mode and amplitude-based binning in 12 respiratory stages, minimizing residual motion artifacts. Torso and lung volumes were calculated using threshold-based segmentation algorithms and volume changes were calculated relative to the full-exhalation stage. The TVC and AVC, as functions of respiratory stages, were compared, showing a high correlation (r = 0.992 ± 0.005, p 2 = 0.980) without phase shift. The AVC was also compared to the spirometric tidal volumes, showing a similar linearity (slope = 1.030 ± 0.092, R 2 = 0.947). In contrast, the thoracic and abdominal heights measured from 4DCT showed relatively low correlation (0.28 ± 0.44 and 0.82 ± 0.30, respectively) and location-dependent phase shifts. This novel approach establishes the foundation for developing an external volumetric respiratory surrogate.

A new methodological approach to assess cardiac work by pressure-volume and stress-length relations in patients with aortic valve stenosis and dilated cardiomyopathy.

Science.gov (United States)

Alter, P; Rupp, H; Rominger, M B; Klose, K J; Maisch, B

2008-01-01

In experimental animals, cardiac work is derived from pressure-volume area and analyzed further using stress-length relations. Lack of methods for determining accurately myocardial mass has until now prevented the use of stress-length relations in patients. We hypothesized, therefore, that not only pressure-volume loops but also stress-length diagrams can be derived from cardiac volume and cardiac mass as assessed by cardiac magnetic resonance imaging (CMR) and invasively measured pressure. Left ventricular (LV) volume and myocardial mass were assessed in seven patients with aortic valve stenosis (AS), eight with dilated cardiomyopathy (DCM), and eight controls using electrocardiogram (ECG)-gated CMR. LV pressure was measured invasively. Pressure-volume curves were calculated based on ECG triggering. Stroke work was assessed as area within the pressure-volume loop. LV wall stress was calculated using a thick-wall sphere model. Similarly, stress-length loops were calculated to quantify stress-length-based work. Taking the LV geometry into account, the normalization with regard to ventricular circumference resulted in "myocardial work." Patients with AS (valve area 0.73+/-0.18 cm(2)) exhibited an increased LV myocardial mass when compared with controls (Pwork of AS was unchanged when compared with controls (0.539+/-0.272 vs 0.621+/-0.138 Nm, not significant), whereas DCM exhibited a significant depression (0.367+/-0.157 Nm, Pwork was significantly reduced in both AS and DCM when compared with controls (129.8+/-69.6, 200.6+/-80.1, 332.2+/-89.6 Nm/m(2), Pmethodological approach of using CMR and invasive pressure measurement. Myocardial work was reduced in patients with DCM and noteworthy also in AS, while stroke work was reduced in DCM only. Most likely, deterioration of myocardial work is crucial for the prognosis. It is suggested to include these basic physiological procedures in the clinical assessment of the pump function of the heart.

Phonons: Theory and experiments II. Volume 2

International Nuclear Information System (INIS)

Bruesch, P.

1986-01-01

The present second volume titled as ''Phonons: Theory and Experiments II'', contains, a thorough study of experimental techniques and the interpretation of experimental results. This three-volume set tries to bridge the gap between theory and experiment, and is addressed to those working in both camps in the vast field of dynamical properties of solids. Topics presented in the second volume include; infrared-, Raman and Brillouin spectroscopy, interaction of X-rays with phonons, and inelastic neutron scattering. In addition an account is given of some other techniques, including ultrasonic methods, inelastic electron tunneling spectroscopy, point contact spectroscopy, and spectroscopy of surface phonons, thin films and adsorbates. Both experimental aspects and theoretical concepts necessary for the interpretation of experimental data are discussed. An attempt is made to present the descriptive as well as the analytical aspects of the topics. Simple models are often used to illustrate the basic concepts and more than 100 figures are included to illustrate both theoretical and experimental results. Many chapters contain a number of problems with hints and results giving additional information

Ground and Space Radar Volume Matching and Comparison Software

Science.gov (United States)

Morris, Kenneth; Schwaller, Mathew

2010-01-01

This software enables easy comparison of ground- and space-based radar observations. The software was initially designed to compare ground radar reflectivity from operational, ground based Sand C-band meteorological radars with comparable measurements from the Tropical Rainfall Measuring Mission (TRMM) satellite s Precipitation Radar (PR) instrument. The software is also applicable to other ground-based and space-based radars. The ground and space radar volume matching and comparison software was developed in response to requirements defined by the Ground Validation System (GVS) of Goddard s Global Precipitation Mission (GPM) project. This software innovation is specifically concerned with simplifying the comparison of ground- and spacebased radar measurements for the purpose of GPM algorithm and data product validation. This software is unique in that it provides an operational environment to routinely create comparison products, and uses a direct geometric approach to derive common volumes of space- and ground-based radar data. In this approach, spatially coincident volumes are defined by the intersection of individual space-based Precipitation Radar rays with the each of the conical elevation sweeps of the ground radar. Thus, the resampled volume elements of the space and ground radar reflectivity can be directly compared to one another.

Advanced Process Chains for Prototyping and Pilot Production based on Additive Manufacturing

DEFF Research Database (Denmark)

Mischkot, Michael

2015-01-01

For many years, Additive Manufacturing (AM) has been a well-established production technology used mainly for rapid prototyping. But the need for increased flexibility and economic low volume production led to the discovery of Additive Manufacturing as a suitable fabrication technique (Mellor 2013...

PENINGKATAN KADAR GERANIOL DALAM MINYAK SEREH WANGI DAN APLIKASINYA SEBAGAI BIO ADDITIVE GASOLINE

Directory of Open Access Journals (Sweden)

Widi Astuti

2014-10-01

Full Text Available Sereh wangi merupakan salah satu tanaman penghasil minyak atsiri yang banyak mengandung geraniol. Geraniol merupakan senyawa penyedia oksigen sehingga minyak sereh wangi dimungkinkan dapat digunakan sebagai bio additive gasoline. Penelitian ini bertujuan  meningkatkan kadar geraniol dalam minyak sereh wangi dan menggunakannya sebagai bio additive gasoline.Penelitian dilakukan dalam  tiga tahap, yaitu  pemungutan minyak sereh wangi dari daun sereh wangi, peningkatan kadar geraniol dalam minyak sereh wangi dan aplikasi minyak sereh wangi yang mengandung geraniol tinggi sebagai bio aditive gasoline.Hasil penelitian menunjukkan bahwa pemungutan minyak sereh wangi yang dilakukan dengan metode distilasi uap menghasilkan rendemen sebesar 0,76% dengan kadar geraniol 5,36%.Kadar geraniol dapat ditingkatkan menjadi 21,78% melalui proses distilasi vakum pada suhu 120oC. Pengujian minyak sereh wangi dengan kadar geraniol tinggi sebagai bio additive gasoline meliputi uji performa dan efisiensi konsumsi bahan bakar dengan variasi perbandingan volume gasoline dengan bio additive. Hasilnya, penambahan minyak sereh wangi dengan perbandingan volume gasoline ; minyak sereh wangi = 1000:2 mampu meningkatkan power mesin dari 7,8HP menjadi 8,6HP. Sementara, pada pengujian efisiensi bahan bakar, penambahan minyak sereh wangi dengan perbandingan volume gasoline : minyak sereh wangi = 1000:2 dapat meningkatkan efisiensi mesin sebesar 10,8%. Citronella contains geraniol which is an oxygen provider substances, so it may be used as bio additive. The purpose of this research  is to increase geraniol content in citronella oil and use it as a gasoline bio additive. This research is conducted  in three steps including take the citronella oil from citronella leaf, increase geraniol content in citronella oil and use citronella oil as a gasoline bio additive. The result show that citronella oil produced from citronella leaf using vapor distillation method contains geraniol

Eschenmoser Approach to Vitamin B

Indian Academy of Sciences (India)

Home; Journals; Resonance – Journal of Science Education; Volume 19; Issue 7. Eschenmoser Approach to Vitamin B12 by A/D Strategy: An Unexpected Journey. G Wayne Craig. General Article Volume 19 Issue 7 July 2014 pp 624-640. Fulltext. Click here to view fulltext PDF. Permanent link:

Reducing surgery of volume for the pulmonary emphysema

International Nuclear Information System (INIS)

Ramirez, Juan Camilo

1997-01-01

The paper includes aspects as selection approaches, functional evaluation, imagenologic evaluation, cardiovascular evaluation, technical aspects and results among other topics related with the reducing surgery of volume of the pulmonary emphysema

New approaches in intelligent control techniques, methodologies and applications

CERN Document Server

Kountchev, Roumen

2016-01-01

This volume introduces new approaches in intelligent control area from both the viewpoints of theory and application. It consists of eleven contributions by prominent authors from all over the world and an introductory chapter. This volume is strongly connected to another volume entitled "New Approaches in Intelligent Image Analysis" (Eds. Roumen Kountchev and Kazumi Nakamatsu). The chapters of this volume are self-contained and include summary, conclusion and future works. Some of the chapters introduce specific case studies of various intelligent control systems and others focus on intelligent theory based control techniques with applications. A remarkable specificity of this volume is that three chapters are dealing with intelligent control based on paraconsistent logics.

Finite volume form factors in the presence of integrable defects

International Nuclear Information System (INIS)

Bajnok, Z.; Buccheri, F.; Hollo, L.; Konczer, J.; Takacs, G.

2014-01-01

We developed the theory of finite volume form factors in the presence of integrable defects. These finite volume form factors are expressed in terms of the infinite volume form factors and the finite volume density of states and incorporate all polynomial corrections in the inverse of the volume. We tested our results, in the defect Lee–Yang model, against numerical data obtained by truncated conformal space approach (TCSA), which we improved by renormalization group methods adopted to the defect case. To perform these checks we determined the infinite volume defect form factors in the Lee–Yang model exactly, including their vacuum expectation values. We used these data to calculate the two point functions, which we compared, at short distance, to defect CFT. We also derived explicit expressions for the exact finite volume one point functions, which we checked numerically. In all of these comparisons excellent agreement was found

Constrained reaction volume approach for studying chemical kinetics behind reflected shock waves

KAUST Repository

Hanson, Ronald K.; Pang, Genny A.; Chakraborty, Sreyashi; Ren, Wei; Wang, Shengkai; Davidson, David Frank

2013-01-01

We report a constrained-reaction-volume strategy for conducting kinetics experiments behind reflected shock waves, achieved in the present work by staged filling in a shock tube. Using hydrogen-oxygen ignition experiments as an example, we

Correlation among body height, intelligence, and brain gray matter volume in healthy children.

Science.gov (United States)

Taki, Yasuyuki; Hashizume, Hiroshi; Sassa, Yuko; Takeuchi, Hikaru; Asano, Michiko; Asano, Kohei; Kotozaki, Yuka; Nouchi, Rui; Wu, Kai; Fukuda, Hiroshi; Kawashima, Ryuta

2012-01-16

A significant positive correlation between height and intelligence has been demonstrated in children. Additionally, intelligence has been associated with the volume of gray matter in the brains of children. Based on these correlations, we analyzed the correlation among height, full-scale intelligence quotient (IQ) and gray matter volume applying voxel-based morphometry using data from the brain magnetic resonance images of 160 healthy children aged 5-18 years of age. As a result, body height was significantly positively correlated with brain gray matter volume. Additionally, the regional gray matter volume of several regions such as the bilateral prefrontal cortices, temporoparietal region, and cerebellum was significantly positively correlated with body height and that the gray matter volume of several of these regions was also significantly positively correlated with full-scale intelligence quotient (IQ) scores after adjusting for age, sex, and socioeconomic status. Our results demonstrate that gray and white matter volume may mediate the correlation between body height and intelligence in healthy children. Additionally, the correlations among gray and white matter volume, height, and intelligence may be at least partially explained by the effect of insulin-like growth factor-1 and growth hormones. Given the importance of the effect of environmental factors, especially nutrition, on height, IQ, and gray matter volume, the present results stress the importance of nutrition during childhood for the healthy maturation of body and brain. Copyright © 2011 Elsevier Inc. All rights reserved.

Comparison of Moving Boundary and Finite-Volume Heat Exchanger Models in the Modelica Language

Directory of Open Access Journals (Sweden)

Adriano Desideri

2016-05-01

Full Text Available When modeling low capacity energy systems, such as a small size (5–150 kWel organic Rankine cycle unit, the governing dynamics are mainly concentrated in the heat exchangers. As a consequence, the accuracy and simulation speed of the higher level system model mainly depend on the heat exchanger model formulation. In particular, the modeling of thermo-flow systems characterized by evaporation or condensation requires heat exchanger models capable of handling phase transitions. To this aim, the finite volume (FV and the moving boundary (MB approaches are the most widely used. The two models are developed and included in the open-source ThermoCycle Modelica library. In this contribution, a comparison between the two approaches is presented. An integrity and accuracy test is designed to evaluate the performance of the FV and MB models during transient conditions. In order to analyze how the two modeling approaches perform when integrated at a system level, two organic Rankine cycle (ORC system models are built using the FV and the MB evaporator model, and their responses are compared against experimental data collected on an 11 kWel ORC power unit. Additionally, the effect of the void fraction value in the MB evaporator model and of the number of control volumes (CVs in the FV one is investigated. The results allow drawing general guidelines for the development of heat exchanger dynamic models involving two-phase flows.

A numerical-statistical approach to determining the representative elementary volume (REV of cement paste for measuring diffusivity

Directory of Open Access Journals (Sweden)

Zhang, M. Z.

2010-12-01

Full Text Available Concrete diffusivity is a function of its microstructure on many scales, ranging from nanometres to millimetres. Multi-scale techniques are therefore needed to model this parameter. Representative elementary volume (REV, in conjunction with the homogenization principle, is one of the most common multi-scale approaches. This study aimed to establish a procedure for establishing the REV required to determine cement paste diffusivity based on a three-step, numerical-statistical approach. First, several series of 3D cement paste microstructures were generated with HYMOSTRUC3D, a cement hydration and microstructure model, for different volumes of cement paste and w/c ratios ranging from 0.30 to 0.60. Second, the finite element method was used to simulate the diffusion of tritiated water through these microstructures. Effective cement paste diffusivity values for different REVs were obtained by applying Fick’s law. Finally, statistical analysis was used to find the fluctuation in effective diffusivity with cement paste volume, from which the REV was then determined. The conclusion drawn was that the REV for measuring diffusivity in cement paste is 100x100x100 μm³.

La difusividad del hormigón depende de su microestructura a numerosas escalas, desde nanómetros hasta milímetros, por lo que se precisa de técnicas multiescala para representar este parámetro. Junto con el principio de homogeneización, uno de los métodos multiescala más habituales es el volumen elemental representativo (VER. El objeto de este estudio era establecer un procedimiento que permitiera determinar el VER necesario para calcular la difusividad de la pasta de cemento, basándose en un método numéricoestadístico que consta de tres etapas. Primero, se crearon varias series de microestructuras de pasta de cemento en 3D con HYMOSTRUC3D, un programa que permite crear un modelo de la hidratación y microestructura del cemento. Luego se empleó el método de

Hole-expansion formability of dual-phase steels using representative volume element approach with boundary-smoothing technique

International Nuclear Information System (INIS)

Kim, Ji Hoon; Lee, M.G.; Kim, D.; Matlock, D.K.; Wagoner, R.H.

2010-01-01

Research highlights: → Robust microstructure-based FE mesh generation technique was developed. → Local deformation behavior near phase boundaries could be quantitatively understood. → Macroscopic failure could be connected to microscopic deformation behavior of multi-phase steel. - Abstract: A qualitative analysis was carried out on the formability of dual-phase (DP) steels by introducing a realistic microstructure-based finite element approach. The present microstructure-based model was constructed using a mesh generation process with a boundary-smoothing algorithm after proper image processing. The developed model was applied to hole-expansion formability tests for DP steel sheets having different volume fractions and morphological features. On the basis of the microstructural inhomogeneity observed in the scanning electron micrographs of the DP steel sheets, it was inferred that the localized plastic deformation in the ferritic phase might be closely related to the macroscopic formability of DP steel. The experimentally observed difference between the hole-expansion formability of two different microstructures was reasonably explained by using the present finite element model.

Between and beyond additivity and non-additivity : the statistical modelling of genotype by environment interaction in plant breeding

OpenAIRE

Eeuwijk, van, F.A.

1996-01-01

In plant breeding it is a common observation to see genotypes react differently to environmental changes. This phenomenon is called genotype by environment interaction. Many statistical approaches for analysing genotype by environment interaction rely heavily on the analysis of variance model. Genotype by environment interaction is then taken to be equivalent to non-additivity. This thesis criticizes the analysis of variance approach. Modelling genotype by environment interaction by non-addit...

Semantics by analogy for illustrative volume visualization

NARCIS (Netherlands)

Gerl, Moritz; Rautek, Peter; Isenberg, Tobias; Groeller, Eduard

We present an interactive graphical approach for the explicit specification of semantics for volume visualization. This explicit and graphical specification of semantics for volumetric features allows us to visually assign meaning to both input and output parameters of the visualization mapping.

Constrained reaction volume approach for studying chemical kinetics behind reflected shock waves

KAUST Repository

Hanson, Ronald K.

2013-09-01

We report a constrained-reaction-volume strategy for conducting kinetics experiments behind reflected shock waves, achieved in the present work by staged filling in a shock tube. Using hydrogen-oxygen ignition experiments as an example, we demonstrate that this strategy eliminates the possibility of non-localized (remote) ignition in shock tubes. Furthermore, we show that this same strategy can also effectively eliminate or minimize pressure changes due to combustion heat release, thereby enabling quantitative modeling of the kinetics throughout the combustion event using a simple assumption of specified pressure and enthalpy. We measure temperature and OH radical time-histories during ethylene-oxygen combustion behind reflected shock waves in a constrained reaction volume and verify that the results can be accurately modeled using a detailed mechanism and a specified pressure and enthalpy constraint. © 2013 The Combustion Institute.

Lighting design for globally illuminated volume rendering.

Science.gov (United States)

Zhang, Yubo; Ma, Kwan-Liu

2013-12-01

With the evolution of graphics hardware, high quality global illumination becomes available for real-time volume rendering. Compared to local illumination, global illumination can produce realistic shading effects which are closer to real world scenes, and has proven useful for enhancing volume data visualization to enable better depth and shape perception. However, setting up optimal lighting could be a nontrivial task for average users. There were lighting design works for volume visualization but they did not consider global light transportation. In this paper, we present a lighting design method for volume visualization employing global illumination. The resulting system takes into account view and transfer-function dependent content of the volume data to automatically generate an optimized three-point lighting environment. Our method fully exploits the back light which is not used by previous volume visualization systems. By also including global shadow and multiple scattering, our lighting system can effectively enhance the depth and shape perception of volumetric features of interest. In addition, we propose an automatic tone mapping operator which recovers visual details from overexposed areas while maintaining sufficient contrast in the dark areas. We show that our method is effective for visualizing volume datasets with complex structures. The structural information is more clearly and correctly presented under the automatically generated light sources.

Finite-volume and partial quenching effects in the magnetic polarizability of the neutron

Science.gov (United States)

Hall, J. M. M.; Leinweber, D. B.; Young, R. D.

2014-03-01

There has been much progress in the experimental measurement of the electric and magnetic polarizabilities of the nucleon. Similarly, lattice QCD simulations have recently produced dynamical QCD results for the magnetic polarizability of the neutron approaching the chiral regime. In order to compare the lattice simulations with experiment, calculation of partial quenching and finite-volume effects is required prior to an extrapolation in quark mass to the physical point. These dependencies are described using chiral effective field theory. Corrections to the partial quenching effects associated with the sea-quark-loop electric charges are estimated by modeling corrections to the pion cloud. These are compared to the uncorrected lattice results. In addition, the behavior of the finite-volume corrections as a function of pion mass is explored. Box sizes of approximately 7 fm are required to achieve a result within 5% of the infinite-volume result at the physical pion mass. A variety of extrapolations are shown at different box sizes, providing a benchmark to guide future lattice QCD calculations of the magnetic polarizabilities. A relatively precise value for the physical magnetic polarizability of the neutron is presented, βn=1.93(11)stat(11)sys×10-4 fm3, which is in agreement with current experimental results.

Advances in 3D printing & additive manufacturing technologies

CERN Document Server

Pandey, Pulak; Kumar, L

2017-01-01

This edited volume comprises select chapters on advanced technologies for 3D printing and additive manufacturing and how these technologies have changed the face of direct, digital technologies for rapid production of models, prototypes and patterns. Because of its wide applications, 3D printing and additive manufacturing technology has become a powerful new industrial revolution in the field of manufacturing. The evolution of 3D printing and additive manufacturing technologies has changed design, engineering and manufacturing processes across industries such as consumer products, aerospace, medical devices and automotives. The objective of this book is to help designers, R&D personnel, and practicing engineers understand the state-of-the-art developments in the field of 3D Printing and Additive Manufacturing. .

Comparative assessment of TRU waste forms and processes. Volume II. Waste form data, process descriptions, and costs

International Nuclear Information System (INIS)

Ross, W.A.; Lokken, R.O.; May, R.P.; Roberts, F.P.; Thornhill, R.E.; Timmerman, C.L.; Treat, R.L.; Westsik, J.H. Jr.

1982-09-01

This volume contains supporting information for the comparative assessment of the transuranic waste forms and processes summarized in Volume I. Detailed data on the characterization of the waste forms selected for the assessment, process descriptions, and cost information are provided. The purpose of this volume is to provide additional information that may be useful when using the data in Volume I and to provide greater detail on particular waste forms and processes. Volume II is divided into two sections and two appendixes. The first section provides information on the preparation of the waste form specimens used in this study and additional characterization data in support of that in Volume I. The second section includes detailed process descriptions for the eight processes evaluated. Appendix A lists the results of MCC-1 leach test and Appendix B lists additional cost data. 56 figures, 12 tables

Real-time bladder volume monitoring by the application of a new implantable bladder volume sensor for a small animal model

Directory of Open Access Journals (Sweden)

Dong Sup Lee

2011-04-01

Full Text Available Although real-time monitoring of bladder volume together with intravesical pressure can provide more information for understanding the functional changes of the urinary bladder, it still entails difficulties in the accurate prediction of real-time bladder volume in urodynamic studies with small animal models. We studied a new implantable bladder volume monitoring device with eight rats. During cystometry, microelectrodes prepared by the microelectromechanical systems process were placed symmetrically on both lateral walls of the bladder, and the expanded bladder volume was calculated. Immunohistological study was done after 1 week and after 4 weeks to evaluate the biocompatibility of the microelectrode. From the point that infused saline volume into the bladder was higher than 0.6 mL, estimated bladder volume was statistically correlated with the volume of saline injected (p<0.01. Additionally, the microelectromechanical system microelectrodes used in this study showed reliable biocompatibility. Therefore, the device can be used to evaluate changes in bladder volume in studies with small animals, and it may help to provide more information about functional changes in the bladder in laboratory studies. Furthermore, owing to its biocompatibility, the device could be chronically implanted in conscious ambulating animals, thus allowing a novel longitudinal study to be performed for a specific purpose.

Combining high-resolution satellite images and altimetry to estimate the volume of small lakes

Science.gov (United States)

Baup, F.; Frappart, F.; Maubant, J.

2014-05-01

This study presents an approach to determining the volume of water in small lakes (manager of the lake. Three independent approaches are developed to estimate the lake volume and its temporal variability. The first two approaches (HRBV and ABV) are empirical and use synchronous ground measurements of the water volume and the satellite data. The results demonstrate that altimetry and imagery can be effectively and accurately used to monitor the temporal variations of the lake (R2ABV = 0.98, RMSEABV = 5%, R2HRBV = 0.90, and RMSEABV = 7.4%), assuming a time-varying triangular shape for the shore slope of the lake (this form is well adapted since it implies a difference inferior to 2% between the theoretical volume of the lake and the one estimated from bathymetry). The third method (AHRBVC) combines altimetry (to measure the lake level) and satellite images (of the lake surface) to estimate the volume changes of the lake and produces the best results (R2AHRBVC = 0.98) of the three methods, demonstrating the potential of future Sentinel and SWOT missions to monitor small lakes and reservoirs for agricultural and irrigation applications.

Quantitative prediction of respiratory tidal volume based on the external torso volume change: a potential volumetric surrogate

Energy Technology Data Exchange (ETDEWEB)

Li Guang; Arora, Naveen C; Xie Huchen; Ning, Holly; Citrin, Deborah; Kaushal, Aradhana; Zach, Leor; Camphausen, Kevin; Miller, Robert W [Radiation Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892 (United States); Lu Wei; Low, Daniel [Department of Radiation Oncology, Washington University School of Medicine, St Louis, MO 63110 (United States)], E-mail: ligeorge@mail.nih.gov

2009-04-07

An external respiratory surrogate that not only highly correlates with but also quantitatively predicts internal tidal volume should be useful in guiding four-dimensional computed tomography (4DCT), as well as 4D radiation therapy (4DRT). A volumetric surrogate should have advantages over external fiducial point(s) for monitoring respiration-induced motion of the torso, which deforms in synchronization with a patient-specific breathing pattern. This study establishes a linear relationship between the external torso volume change (TVC) and lung air volume change (AVC) by validating a proposed volume conservation hypothesis (TVC = AVC) throughout the respiratory cycle using 4DCT and spirometry. Fourteen patients' torso 4DCT images and corresponding spirometric tidal volumes were acquired to examine this hypothesis. The 4DCT images were acquired using dual surrogates in cine mode and amplitude-based binning in 12 respiratory stages, minimizing residual motion artifacts. Torso and lung volumes were calculated using threshold-based segmentation algorithms and volume changes were calculated relative to the full-exhalation stage. The TVC and AVC, as functions of respiratory stages, were compared, showing a high correlation (r = 0.992 {+-} 0.005, p < 0.0001) as well as a linear relationship (slope = 1.027 {+-} 0.061, R{sup 2} = 0.980) without phase shift. The AVC was also compared to the spirometric tidal volumes, showing a similar linearity (slope = 1.030 {+-} 0.092, R{sup 2} = 0.947). In contrast, the thoracic and abdominal heights measured from 4DCT showed relatively low correlation (0.28 {+-} 0.44 and 0.82 {+-} 0.30, respectively) and location-dependent phase shifts. This novel approach establishes the foundation for developing an external volumetric respiratory surrogate.

Control volume based modelling of compressible flow in reciprocating machines

DEFF Research Database (Denmark)

Andersen, Stig Kildegård; Thomsen, Per Grove; Carlsen, Henrik

2004-01-01

, and multidimensional effects must be calculated using empirical correlations; correlations for steady state flow can be used as an approximation. A transformation that assumes ideal gas is presented for transforming equations for masses and energies in control volumes into the corresponding pressures and temperatures......An approach to modelling unsteady compressible flow that is primarily one dimensional is presented. The approach was developed for creating distributed models of machines with reciprocating pistons but it is not limited to this application. The approach is based on the integral form of the unsteady...... conservation laws for mass, energy, and momentum applied to a staggered mesh consisting of two overlapping strings of control volumes. Loss mechanisms can be included directly in the governing equations of models by including them as terms in the conservation laws. Heat transfer, flow friction...

An Integrated Approach to Biology

Indian Academy of Sciences (India)

Home; Journals; Resonance – Journal of Science Education; Volume 16; Issue 8. An Integrated Approach to Biology. Aniket Bhattacharya. General Article Volume 16 Issue 8 August 2011 pp 742-753. Fulltext. Click here to view fulltext PDF. Permanent link: https://www.ias.ac.in/article/fulltext/reso/016/08/0742-0753 ...

The molar hydrodynamic volume changes of factor VIIa due to GlycoPEGylation

DEFF Research Database (Denmark)

Plesner, Bitten; Westh, Peter; Hvidt, Søren

2011-01-01

The effects of GlycoPEGylation on the molar hydrodynamic volume of recombinant human rFVIIa were investigated using rFVIIa and two GlycoPEGylated recombinant human FVIIa derivatives, a linear 10 kDa PEG and a branched 40 kDa PEG, respectively. Molar hydrodynamic volumes were determined by capillary......, that the molar hydrodynamic volume of the conjugated protein is not just an addition of the molar hydrodynamic volume of the PEG and the protein. The molar hydrodynamic volume of the GlycoPEGylated protein is larger than the volume of its composites. These results suggest that both the linear and the branched...

Simulation-based comparison of two approaches frequently used for dynamic contrast-enhanced MRI

International Nuclear Information System (INIS)

Zwick, Stefan; Brix, Gunnar; Tofts, Paul S.; Strecker, Ralph; Kopp-Schneider, Annette; Laue, Hendrik; Semmler, Wolfhard; Kiessling, Fabian

2010-01-01

The purpose was to compare two approaches for the acquisition and analysis of dynamic-contrast-enhanced MRI data with respect to differences in the modelling of the arterial input-function (AIF), the dependency of the model parameters on physiological parameters and their numerical stability. Eight hundred tissue concentration curves were simulated for different combinations of perfusion, permeability, interstitial volume and plasma volume based on two measured AIFs and analysed according to the two commonly used approaches. The transfer constants (Approach 1) K trans and (Approach 2) k ep were correlated with all tissue parameters. K trans showed a stronger dependency on perfusion, and k ep on permeability. The volume parameters (Approach 1) v e and (Approach 2) A were mainly influenced by the interstitial and plasma volume. Both approaches allow only rough characterisation of tissue microcirculation and microvasculature. Approach 2 seems to be somewhat more robust than 1, mainly due to the different methods of CA administration. (orig.)

Artificial Neural Network-Based System for PET Volume Segmentation

Directory of Open Access Journals (Sweden)

Mhd Saeed Sharif

2010-01-01

Full Text Available Tumour detection, classification, and quantification in positron emission tomography (PET imaging at early stage of disease are important issues for clinical diagnosis, assessment of response to treatment, and radiotherapy planning. Many techniques have been proposed for segmenting medical imaging data; however, some of the approaches have poor performance, large inaccuracy, and require substantial computation time for analysing large medical volumes. Artificial intelligence (AI approaches can provide improved accuracy and save decent amount of time. Artificial neural networks (ANNs, as one of the best AI techniques, have the capability to classify and quantify precisely lesions and model the clinical evaluation for a specific problem. This paper presents a novel application of ANNs in the wavelet domain for PET volume segmentation. ANN performance evaluation using different training algorithms in both spatial and wavelet domains with a different number of neurons in the hidden layer is also presented. The best number of neurons in the hidden layer is determined according to the experimental results, which is also stated Levenberg-Marquardt backpropagation training algorithm as the best training approach for the proposed application. The proposed intelligent system results are compared with those obtained using conventional techniques including thresholding and clustering based approaches. Experimental and Monte Carlo simulated PET phantom data sets and clinical PET volumes of nonsmall cell lung cancer patients were utilised to validate the proposed algorithm which has demonstrated promising results.

Role of aluminium addition on structure of Fe substituted Fe73· 5 ...

Indian Academy of Sciences (India)

2016-08-26

Aug 26, 2016 ... Home; Journals; Bulletin of Materials Science; Volume 36; Issue 4. Role of aluminium addition on structure of Fe substituted Fe73.5−Si13.5B9Nb3Cu1Al alloy ribbons. Gautam Agarwal Himanshu Agrawal M Srinivas B Majumdar N K Mukhopadhyay. Volume 36 Issue 4 August 2013 pp 613-618 ...

75 FR 26316 - Allocation of Additional Fiscal Year (FY) 2010 In-Quota Volume for Raw Cane Sugar

Science.gov (United States)

2010-05-11

...-Quota Volume for Raw Cane Sugar AGENCY: Office of the United States Trade Representative. ACTION: Notice...) for imported raw cane sugar. DATES: Effective Date: May 11, 2010. ADDRESSES: Inquiries may be mailed... (HTS), the United States maintains TRQs for imports of raw cane and refined sugar. Section 404(d)(3) of...

Fluid Mechanics Of Molten Metal Droplets In Additive Manufacturing

Czech Academy of Sciences Publication Activity Database

Tesař, Václav; Šonský, Jiří

2016-01-01

Roč. 4, č. 4 (2016), s. 403-412 ISSN 2046-0546 R&D Projects: GA ČR GA13-23046S Institutional support: RVO:61388998 Keywords : additive manufacturing * droplets * molten metal Subject RIV: BK - Fluid Dynamics http://www.witpress.com/elibrary/cmem-volumes/4/4/1545

Image registration with auto-mapped control volumes

International Nuclear Information System (INIS)

Schreibmann, Eduard; Xing Lei

2006-01-01

Many image registration algorithms rely on the use of homologous control points on the two input image sets to be registered. In reality, the interactive identification of the control points on both images is tedious, difficult, and often a source of error. We propose a two-step algorithm to automatically identify homologous regions that are used as a priori information during the image registration procedure. First, a number of small control volumes having distinct anatomical features are identified on the model image in a somewhat arbitrary fashion. Instead of attempting to find their correspondences in the reference image through user interaction, in the proposed method, each of the control regions is mapped to the corresponding part of the reference image by using an automated image registration algorithm. A normalized cross-correlation (NCC) function or mutual information was used as the auto-mapping metric and a limited memory Broyden-Fletcher-Goldfarb-Shanno algorithm (L-BFGS) was employed to optimize the function to find the optimal mapping. For rigid registration, the transformation parameters of the system are obtained by averaging that derived from the individual control volumes. In our deformable calculation, the mapped control volumes are treated as the nodes or control points with known positions on the two images. If the number of control volumes is not enough to cover the whole image to be registered, additional nodes are placed on the model image and then located on the reference image in a manner similar to the conventional BSpline deformable calculation. For deformable registration, the established correspondence by the auto-mapped control volumes provides valuable guidance for the registration calculation and greatly reduces the dimensionality of the problem. The performance of the two-step registrations was applied to three rigid registration cases (two PET-CT registrations and a brain MRI-CT registration) and one deformable registration of

Thermal Diffusivity and Thermal Conductivity of Dispersed Glass Sphere Composites Over a Range of Volume Fractions

Science.gov (United States)

Carson, James K.

2018-06-01

Glass spheres are often used as filler materials for composites. Comparatively few articles in the literature have been devoted to the measurement or modelling of thermal properties of composites containing glass spheres, and there does not appear to be any reported data on the measurement of thermal diffusivities over a range of filler volume fractions. In this study, the thermal diffusivities of guar-gel/glass sphere composites were measured using a transient comparative method. The addition of the glass beads to the gel increased the thermal diffusivity of the composite, more than doubling the thermal diffusivity of the composite relative to the diffusivity of the gel at the maximum glass volume fraction of approximately 0.57. Thermal conductivities of the composites were derived from the thermal diffusivity measurements, measured densities and estimated specific heat capacities of the composites. Two approaches to modelling the effective thermal diffusivity were considered.

Understanding the influence of buckwheat bran on wheat dough baking performance: Mechanistic insights from molecular and material science approaches.

Science.gov (United States)

Zanoletti, Miriam; Marti, Alessandra; Marengo, Mauro; Iametti, Stefania; Pagani, M Ambrogina; Renzetti, Stefano

2017-12-01

A molecular and material science approach is used to describe the influence of coarse and fine buckwheat bran on wheat dough properties and bread textural quality. Focus is given on (i) gluten solvation and structural arrangements in presence of bran as studied by front-face fluorescence; (ii) thermo-mechanical behavior of dough during heating studied by dynamic mechanical thermal analysis and (iii) texture of bread crumb analyzed in terms of a cellular solid. The thermo-mechanical behavior of dough was found to be largely related to starch phase transitions during heating. The use of thermodynamic approaches to biopolymer melting revealed that key transitions such as the onset of starch gelatinization were function of the interplay of water and bran volume fractions in the dough. Front-face fluorescence studies in wheat dough revealed that gluten solvation and structural arrangements were delayed by increasing bran addition level and reduction in particle size, as indicated by the drastic decrease in the protein surface hydrophobicity index. Variations in gluten structure could be strongly related to dough baking performance, i.e. specific volume. With regards to texture, the approach revealed that crumb texture was controlled by variations in density, moisture and bran volume fractions. Overall, this study elucidates a number of physical mechanisms describing the influence of buckwheat bran addition to dough and bread quality. These mechanisms strongly pointed at the influence of bran on water partitioning among the main polymeric components. In the future, these mechanisms should be investigated with bran material of varying source, composition and structure. Copyright © 2017 Elsevier Ltd. All rights reserved.

Determination of bone mineral volume fraction using impedance analysis and Bruggeman model

Energy Technology Data Exchange (ETDEWEB)

Ciuchi, Ioana Veronica; Olariu, Cristina Stefania, E-mail: oocristina@yahoo.com; Mitoseriu, Liliana, E-mail: lmtsr@uaic.ro

2013-11-20

Highlights: • Mineral volume fraction of a bone sample was determined. • Dielectric properties for bone sample and for the collagen type I were determined by impedance spectroscopy. • Bruggeman effective medium approximation was applied in order to evaluate mineral volume fraction of the sample. • The computed values were compared with ones derived from a histogram test performed on SEM micrographs. -- Abstract: Measurements by impedance spectroscopy and Bruggeman effective medium approximation model were employed in order to determine the mineral volume fraction of dry bone. This approach assumes that two or more phases are present into the composite: the matrix (environment) and the other ones are inclusion phases. A fragment of femur diaphysis dense bone from a young pig was investigated in its dehydrated state. Measuring the dielectric properties of bone and its main components (hydroxyapatite and collagen) and using the Bruggeman approach, the mineral volume filling factor was determined. The computed volume fraction of the mineral volume fraction was confirmed by a histogram test analysis based on the SEM microstructures. In spite of its simplicity, the method provides a good approximation for the bone mineral volume fraction. The method which uses impedance spectroscopy and EMA modeling can be further developed by considering the conductive components of the bone tissue as a non-invasive in situ impedance technique for bone composition evaluation and monitoring.

Determination of bone mineral volume fraction using impedance analysis and Bruggeman model

International Nuclear Information System (INIS)

Ciuchi, Ioana Veronica; Olariu, Cristina Stefania; Mitoseriu, Liliana

2013-01-01

Highlights: • Mineral volume fraction of a bone sample was determined. • Dielectric properties for bone sample and for the collagen type I were determined by impedance spectroscopy. • Bruggeman effective medium approximation was applied in order to evaluate mineral volume fraction of the sample. • The computed values were compared with ones derived from a histogram test performed on SEM micrographs. -- Abstract: Measurements by impedance spectroscopy and Bruggeman effective medium approximation model were employed in order to determine the mineral volume fraction of dry bone. This approach assumes that two or more phases are present into the composite: the matrix (environment) and the other ones are inclusion phases. A fragment of femur diaphysis dense bone from a young pig was investigated in its dehydrated state. Measuring the dielectric properties of bone and its main components (hydroxyapatite and collagen) and using the Bruggeman approach, the mineral volume filling factor was determined. The computed volume fraction of the mineral volume fraction was confirmed by a histogram test analysis based on the SEM microstructures. In spite of its simplicity, the method provides a good approximation for the bone mineral volume fraction. The method which uses impedance spectroscopy and EMA modeling can be further developed by considering the conductive components of the bone tissue as a non-invasive in situ impedance technique for bone composition evaluation and monitoring

Approach to integrate current safeguards measures with additional protocol requirements at national level

International Nuclear Information System (INIS)

Ramirez, R.

2001-01-01

Peru adhered to the Additional Protocol in March 2000 which was also approved by the Congress in May 2001. After approval by law the obligations derived from this Additional Protocol will be in force after 180 days. After the signing of the Protocol an approach was designed to help better fulfill these requirements in an integrated way with the previous measures. As first stage, a review of the current state of safeguards was undertaken. Under the current agreement (an INFCIRC/153 type agreement) the reporting is less complicated and inexpensive to be carried out because these reports include only the declared nuclear material and the features of declared facilities where the nuclear material is used. No other related facility or material or activity needs to be declared. In Peru there are only two MBAs where low enriched uranium (LEU) is used and the record system includes general ledgers, inventory records and operational books. The results of national inspections and copies of reports and communications sent to the IAEA are also kept in this system. Under the agreement and subsidiary arrangements material balance reports (MBR), physical inventory listings (PIL) and inventory change reports (ICR) are prepared and submitted to the IAEA at scheduled periods. The MBR and PIL reports are sent after yearly regular inspections carried out by the IAEA. The ICR is sent just every time when an import or export of nuclear material is made. The time devoted to carry out all of these activities is not so extensive for both the State System for Accountability and Control (SSAC) and the users because of the limited nuclear activities in the country. Because of the characteristics and limited quantities of nuclear material the efforts for inspection and reporting activities are few. Another subject under review was the procedure for controlling the imports of nuclear material. Under the current agreement this subject was not a problem, as all of the radioactive and nuclear

Experimental investigation of the effect of HBr additions on the lasing characteristics of a CuBr laser

International Nuclear Information System (INIS)

Shiyanov, D V; Sukhanov, V B; Andrienko, Oleg S; Evtushenko, Gennadii S

2004-01-01

It was experimentally determined that introducing small additions of HBr into the active elements of a CuBr laser is similar to the addition of hydrogen and significantly improves the output laser parameters. The effect of additions to small-volume active elements is most pronounced (up to a five-fold increase in output power) and is less pronounced in large-volume active elements (up to a twofold increase). A special-purpose HBr generator was elaborated, making it possible to promptly provide the requisite concentration of the active addition in a sealed-off active element. (lasers, active media)

Quantum volume hologram

International Nuclear Information System (INIS)

Vasilyev, Denis V.; Sokolov, Ivan V.; Polzik, Eugene S.

2010-01-01

We propose a scheme for parallel spatially multimode quantum memory for light. The scheme is based on a counterpropagating quantum signal wave and a strong classical reference wave as in a classical volume hologram and therefore can be called a quantum volume hologram. The medium for the hologram consists of a spatially extended ensemble of atoms placed in a magnetic field. The write-in and readout of this quantum hologram is as simple as that of its classical counterpart and consists of a single-pass illumination. In addition, we show that the present scheme for a quantum hologram is less sensitive to diffraction and therefore is capable of achieving a higher density of storage of spatial modes as compared to previous proposals. We present a feasibility study and show that experimental implementation is possible with available cold atomic samples. A quantum hologram capable of storing entangled images can become an important ingredient in quantum information processing and quantum imaging.

The Algebraic versus the Topological Approach to Additive Representations

NARCIS (Netherlands)

P.P. Wakker (Peter)

1988-01-01

textabstractIt is proved that, under a nontriviality assumption, an additive function on a Cartesian product of connected topological spaces is continuous, whenever the preference relation, represented by this function, is continuous. The result is used to generalize a theorem of Debreu ((1960).

Procedures for treating common cause failures in safety and reliability studies: Volume 2, Analytic background and techniques: Final report

International Nuclear Information System (INIS)

Mosleh, A.; Fleming, K.N.; Parry, G.W.; Paula, H.M.; Worledge, D.H.; Rasmuson, D.M.

1988-12-01

This report presents a framework for the inclusion of the impact of common cause failures in risk and reliability evaluations. Common cause failures are defined as that subset of dependent failures for which causes are not explicitly included in the logic model as basic events. The emphasis here is on providing procedures for a practical, systematic approach that can be used to perform and clearly document the analysis. The framework and the methods discussed for performing the different stages of the analysis integrate insights obtained from engineering assessments of the system and the historical evidence from multiple failure events into a systematic, reproducible, and defensible analysis. This document, Volume 2, contains a series of appendices that provide additional background and methodological detail on several important topics discussed in Volume 1

A Research Needs Assessment for waste plastics recycling: Volume 1, Executive summary. Final report

Energy Technology Data Exchange (ETDEWEB)

NONE

1994-12-01

This first volume provides a summary of the entire project. The study utilized the talents of a large number of participants, including a significant number of peer reviewers from industrial companies, government agencies, and research institutes. in addition, an extensive analysis of relevant literature was carried out. In considering the attractiveness of recycling technologies that are alternatives to waste-to-energy combustion units, a systems approach was utilized. Collection of waste streams containing plastics, sortation, and reclamation of plastics and plastic mixtures, reprocessing or chemical conversion of the reclaimed polymers, and the applicability of the products to specific market segments have been analyzed in the study.

Relapse patterns after radiochemotherapy of glioblastoma with FET PET-guided boost irradiation and simulation to optimize radiation target volume

International Nuclear Information System (INIS)

Piroth, Marc D.; Galldiks, Norbert; Pinkawa, Michael; Holy, Richard; Stoffels, Gabriele; Ermert, Johannes; Mottaghy, Felix M.; Shah, N. Jon; Langen, Karl-Josef; Eble, Michael J.

2016-01-01

O-(2-18 F-fluoroethyl)-L-tyrosine-(FET)-PET may be helpful to improve the definition of radiation target volumes in glioblastomas compared with MRI. We analyzed the relapse patterns in FET-PET after a FET- and MRI-based integrated-boost intensity-modulated radiotherapy (IMRT) of glioblastomas to perform an optimized target volume definition. A relapse pattern analysis was performed in 13 glioblastoma patients treated with radiochemotherapy within a prospective phase-II-study between 2008 and 2009. Radiotherapy was performed as an integrated-boost intensity-modulated radiotherapy (IB-IMRT). The prescribed dose was 72 Gy for the boost target volume, based on baseline FET-PET (FET-1) and 60 Gy for the MRI-based (MRI-1) standard target volume. The single doses were 2.4 and 2.0 Gy, respectively. Location and volume of recurrent tumors in FET-2 and MRI-2 were analyzed related to initial tumor, detected in baseline FET-1. Variable target volumes were created theoretically based on FET-1 to optimally cover recurrent tumor. The tumor volume overlap in FET and MRI was poor both at baseline (median 12 %; range 0–32) and at time of recurrence (13 %; 0–100). Recurrent tumor volume in FET-2 was localized to 39 % (12–91) in the initial tumor volume (FET-1). Over the time a shrinking (mean 12 (5–26) ml) and shifting (mean 6 (1–10 mm) of the resection cavity was seen. A simulated target volume based on active tumor in FET-1 with an additional safety margin of 7 mm around the FET-1 volume covered recurrent FET tumor volume (FET-2) significantly better than a corresponding target volume based on contrast enhancement in MRI-1 with a same safety margin of 7 mm (100 % (54–100) versus 85 % (0–100); p < 0.01). A simulated planning target volume (PTV), based on FET-1 and additional 7 mm margin plus 5 mm margin for setup-uncertainties was significantly smaller than the conventional, MR-based PTV applied in this study (median 160 (112–297) ml versus 231 (117–386) ml, p < 0

76 FR 42160 - Allocation of Additional Fiscal Year (FY) 2011 In-Quota Volume for Raw Cane Sugar

Science.gov (United States)

2011-07-18

...-Quota Volume for Raw Cane Sugar AGENCY: Office of the United States Trade Representative. ACTION: Notice...) for imported raw cane sugar. USTR is also reallocating a portion of the unused original FY 2011 TRQ... imports of raw cane and refined sugar. Section 404(d)(3) of the Uruguay Round Agreements Act (19 U.S.C...

Stereological estimation of the mean and variance of nuclear volume from vertical sections

DEFF Research Database (Denmark)

Sørensen, Flemming Brandt

1991-01-01

The application of assumption-free, unbiased stereological techniques for estimation of the volume-weighted mean nuclear volume, nuclear vv, from vertical sections of benign and malignant nuclear aggregates in melanocytic skin tumours is described. Combining sampling of nuclei with uniform...... probability in a physical disector and Cavalieri's direct estimator of volume, the unbiased, number-weighted mean nuclear volume, nuclear vN, of the same benign and malignant nuclear populations is also estimated. Having obtained estimates of nuclear volume in both the volume- and number distribution...... to the larger malignant nuclei. Finally, the variance in the volume distribution of nuclear volume is estimated by shape-independent estimates of the volume-weighted second moment of the nuclear volume, vv2, using both a manual and a computer-assisted approach. The working procedure for the description of 3-D...

Transcranial sonography: integration into target volume definition for glioblastoma multiforme

International Nuclear Information System (INIS)

Vordermark, Dirk; Becker, Georg; Flentje, Michael; Richter, Susanne; Goerttler-Krauspe, Irene; Koelbl, Oliver

2000-01-01

Purpose: Recent studies indicate that transcranial sonography (TCS) reliably displays the extension of malignant brain tumors. The effect of integrating TCS into radiotherapy planning for glioblastoma multiforme (GBM) was investigated herein. Methods and Materials: Thirteen patients subtotally resected for GBM underwent TCS during radiotherapy planning and were conventionally treated (54 to 60 Gy). Gross tumor volumes (GTVs) and stereotactic boost planning target volumes (PTVs, 3-mm margin) were created, based on contrast enhancement on computed tomography (CT) only (PTV CT ) or the combined CT and TCS information (PTV CT+TCS ). Noncoplonar conformal treatment plans for both PTVs were compared. Tumor progression patterns and preoperative magnetic resonance imaging (MRI) were related to both PTVs. Results: A sufficient temporal bone window for TCS was present in 11 of 13 patients. GTVs as defined by TCS were considerably larger than the respective CT volumes: Of the composite GTV CT+TCS (median volume 42 ml), 23%, 13%, and 66% (medians) were covered by the overlap of both methods, CT only and TCS only, respectively. Median sizes of PTV CT and PTV CT+TCS were 34 and 74 ml, respectively. Addition of TCS to CT information led to a median increase of the volume irradiated within the 80% isodose by 32 ml (median factor 1.51). PTV CT+TCS volume was at median 24% of a 'conventional' MRI(T2)-based PTV. Of eight progressions analyzed, three and six occurred inside the 80% isodose of the plans for PTV CT and for PTV CT+TCS , respectively. Conclusion: Addition of TCS tumor volume to the contrast-enhancing CT volume in postoperative radiotherapy planning for GBM increases the treated volume by a median factor of 1.5. Since a high frequency of marginal recurrences is reported from dose-escalation trials of this disease, TCS may complement established methods in PTV definition

The influence of additions of Al and Si on the lattice stability of fcc and hcp Fe-Mn random alloys

Energy Technology Data Exchange (ETDEWEB)

Gebhardt, T; Music, D; Schneider, J M [Materials Chemistry, RWTH Aachen University, D-52056 Aachen (Germany); Ekholm, M; Abrikosov, I A [Department of Physics, Chemistry and Biology (IFM), Linkoeping University, SE-58183 Linkoeping (Sweden); Vitos, L [Department of Materials and Engineering, Applied Materials Physics, Royal Institute of Technology (KTH), SE-10044 Stockholm (Sweden); Dick, A; Hickel, T; Neugebauer, J, E-mail: gebhardt@mch.rwth-aachen.de [Department of Computational Materials Design, Max-Planck-Institut fuer Eisenforschung GmbH, D-40237 Duesseldorf (Germany)

2011-06-22

We have studied the influence of additions of Al and Si on the lattice stability of face-centred-cubic (fcc) versus hexagonal-closed-packed (hcp) Fe-Mn random alloys, considering the influence of magnetism below and above the fcc Neel temperature. Employing two different ab initio approaches with respect to basis sets and treatment of magnetic and chemical disorder, we are able to quantify the predictive power of the ab initio methods. We find that the addition of Al strongly stabilizes the fcc lattice independent of the regarded magnetic states. For Si a much stronger dependence on magnetism is observed. Compared to Al, almost no volume change is observed as Si is added to Fe-Mn, indicating that the electronic contributions are responsible for stabilization/destabilization of the fcc phase.

The influence of additions of Al and Si on the lattice stability of fcc and hcp Fe-Mn random alloys

International Nuclear Information System (INIS)

Gebhardt, T; Music, D; Schneider, J M; Ekholm, M; Abrikosov, I A; Vitos, L; Dick, A; Hickel, T; Neugebauer, J

2011-01-01

We have studied the influence of additions of Al and Si on the lattice stability of face-centred-cubic (fcc) versus hexagonal-closed-packed (hcp) Fe-Mn random alloys, considering the influence of magnetism below and above the fcc Neel temperature. Employing two different ab initio approaches with respect to basis sets and treatment of magnetic and chemical disorder, we are able to quantify the predictive power of the ab initio methods. We find that the addition of Al strongly stabilizes the fcc lattice independent of the regarded magnetic states. For Si a much stronger dependence on magnetism is observed. Compared to Al, almost no volume change is observed as Si is added to Fe-Mn, indicating that the electronic contributions are responsible for stabilization/destabilization of the fcc phase.

Gross tumor volume (GTV) and clinical target volume (CTV) for radiation therapy of benign skull base tumours

International Nuclear Information System (INIS)

Maire, J.P.; Liguoro, D.; San Galli, F.

2001-01-01

Skull base tumours represent a out 35 to 40% of all intracranial tumours. There are now many reports in the literature confirming the fact that about 80 to 90% of such tumours are controlled with fractionated radiotherapy. Stereotactic and 3-dimensional treatment planning techniques increase local control and central nervous system tolerance. Definition of the gross tumor volume (GTV) is generally easy with currently available medical imaging systems and computers for 3-dimensional dosimetry. The definition of the clinical target volume (CTV) is more difficult to appreciate: it is defined from the CTV plus a margin, which depends on the histology and anterior therapeutic history of the tumour. It is important to take into account the visible tumour and its possible extension pathways (adjacent bone, holes at the base of skull) and/or an anatomic region (sella turcica + adjacent cavernous sinus). It is necessary to evaluate these volumes with CT Scan and MRI to appreciate tumor extension in a 3-dimensional approach, in order to reduce the risk of marginal recurrences. The aim of this paper is to discuss volume definition as a function of tumour site and tumour type to be irradiated. (authors)

Accuracy Assessment of Timber Volume Maps Using Forest Inventory Data and LiDAR Canopy Height Models

Directory of Open Access Journals (Sweden)

Andreas Hill

2014-09-01

Full Text Available Maps of standing timber volume provide valuable decision support for forest managers and have therefore been the subject of recent studies. For map production, field observations are commonly combined with area-wide remote sensing data in order to formulate prediction models, which are then applied over the entire inventory area. The accuracy of such maps has frequently been described by parameters such as the root mean square error of the prediction model. The aim of this study was to additionally address the accuracy of timber volume classes, which are used to better represent the map predictions. However, the use of constant class intervals neglects the possibility that the precision of the underlying prediction model may not be constant across the entire volume range, resulting in pronounced gradients between class accuracies. This study proposes an optimization technique that automatically identifies a classification scheme which accounts for the properties of the underlying model and the implied properties of the remote sensing support information. We demonstrate the approach in a mountainous study site in Eastern Switzerland covering a forest area of 2000 hectares using a multiple linear regression model approach. A LiDAR-based canopy height model (CHM provided the auxiliary information; timber volume observations from the latest forest inventory were used for model calibration and map validation. The coefficient of determination (R2 = 0.64 and the cross-validated root mean square error (RMSECV = 123.79 m3 ha−1 were only slightly smaller than those of studies in less steep and heterogeneous landscapes. For a large set of pre-defined number of classes, the optimization model successfully identified those classification schemes that achieved the highest possible accuracies for each class.

Volume Sculpting Using the Level-Set Method

DEFF Research Database (Denmark)

Bærentzen, Jakob Andreas; Christensen, Niels Jørgen

2002-01-01

In this paper, we propose the use of the Level--Set Method as the underlying technology of a volume sculpting system. The main motivation is that this leads to a very generic technique for deformation of volumetric solids. In addition, our method preserves a distance field volume representation....... A scaling window is used to adapt the Level--Set Method to local deformations and to allow the user to control the intensity of the tool. Level--Set based tools have been implemented in an interactive sculpting system, and we show sculptures created using the system....

On the radiation accompanying volume reflection

International Nuclear Information System (INIS)

Bandiera, L.; Bagli, E.; Berra, A.; Bolognini, D.; Dalpiaz, P.; Della Mea, G.; De Salvador, D.; Guidi, V.; Hasan, S.; Lietti, D.; Mazzolari, A.

2013-01-01

The electromagnetic radiation emitted by 120 GeV/c volume-reflected electrons in a bent silicon crystal has been investigated at CERN SPS-H4 beamline. The trajectories of electrons crossing a silicon strip-like crystal have been reconstructed through a telescope system based on high precision micro-strip detectors. The experimental setup was also equipped with a spectrometer and an electromagnetic calorimeter to measure the energy loss of the particles under volume reflection condition. Such a system enabled to record the full photon spectrum up to the nominal energy of the beam. Experimental results were compared to recently developed theoretical approaches based on the quasi-classical operators method of Baier and Katkov

A current approach to using additional foods for the early prevention of deficiency states in infants during the first year of life

Directory of Open Access Journals (Sweden)

L. V. Levchuk

2014-01-01

Full Text Available The paper considers how to organize properly balanced feeding in infants during the first year of life, by using additional foods. It highlights current approaches to using the latter in the babies and provides a rationale for the tune of giving additional foods, by taking into account the readiness of an infant to eat new foods and the need to incorporate micronutrients for the prevention of anemia, rickets, and food allergy. The benefits of using commercial products are discussed.

Volume reduction options for the management of low-level radioactive wastes

International Nuclear Information System (INIS)

Clark, D.E.; Lerch, R.E.

1979-01-01

Volume reduction options that are now or soon will be available for low-level wastes are examined. These wastes generally are in the form of combustible solids, noncombustible solids, and wet wastes (solid/liquid). Initially, the wastes are collected and stored onsite. Preconditioning may be required, e.g., sorting, shredding, and classifying the solids into combustible and noncombustible fractions. The volume of combustible solids can be reduced by compaction, incineration/pyrolysis, acid digestion, or molten salt combustion. Options for reducing the volume of noncombustible solids include compaction, size reduction and decontamination, meltdown-casting, dissolution and electropolishing. Burnable wet wastes (e.g., organic wastes) can be evaporated or combusted; nonburnable wet wastes can be treated by various evaporative or nonevaporative processes. All radioactive waste processing operations result in some equipment contamination and the production of additional radioactively contaminated wastes (secondary wastes). The additional waste quantities must be considered in evaluating performance and overall volume reduction factors for the various systems. In the selection of an optimum waste management plan for a given facility, other important factors (e.g., relative stability of the waste product form) should be considered along with the savings accrued due to volume reduction

Excluded volume effects caused by high concentration addition of acid generators in chemically amplified resists used for extreme ultraviolet lithography

Science.gov (United States)

Kozawa, Takahiro; Watanabe, Kyoko; Matsuoka, Kyoko; Yamamoto, Hiroki; Komuro, Yoshitaka; Kawana, Daisuke; Yamazaki, Akiyoshi

2017-08-01

The resolution of lithography used for the high-volume production of semiconductor devices has been improved to meet the market demands for highly integrated circuits. With the reduction in feature size, the molecular size becomes non-negligible in the resist material design. In this study, the excluded volume effects caused by adding high-concentration acid generators were investigated for triphenylsulfonium nonaflate. The resist film density was measured by X-ray diffractometry. The dependences of absorption coefficient and protected unit concentration on acid generator weight ratio were calculated from the measured film density. Using these values, the effects on the decomposition yield of acid generators, the protected unit fluctuation, and the line edge roughness (LER) were evaluated by simulation on the basis of sensitization and reaction mechanisms of chemically amplified extreme ultraviolet resists. The positive effects of the increase in acid generator weight ratio on LER were predominant below the acid generator weight ratio of 0.3, while the negative effects became equivalent to the positive effects above the acid generator weight ratio of 0.3 owing to the excluded volume effects.

Analysis of Daily Laboratory Orders at a Large Urban Academic Center: A Multifaceted Approach to Changing Test Ordering Patterns.

Science.gov (United States)

Rudolf, Joseph W; Dighe, Anand S; Coley, Christopher M; Kamis, Irina K; Wertheim, Bradley M; Wright, Douglas E; Lewandrowski, Kent B; Baron, Jason M

2017-08-01

We sought to address concerns regarding recurring inpatient laboratory test order practices (daily laboratory tests) through a multifaceted approach to changing ordering patterns. We engaged in an interdepartmental collaboration to foster mindful test ordering through clinical policy creation, electronic clinical decision support, and continuous auditing and feedback. Annualized daily order volumes decreased from approximately 25,000 to 10,000 during a 33-month postintervention review. This represented a significant change from preintervention order volumes (95% confidence interval, 0.61-0.64; P < 10-16). Total inpatient test volumes were not affected. Durable changes to inpatient order practices can be achieved through a collaborative approach to utilization management that includes shared responsibility for establishing clinical guidelines and electronic decision support. Our experience suggests auditing and continued feedback are additional crucial components to changing ordering behavior. Curtailing daily orders alone may not be a sufficient strategy to reduce in-laboratory costs. © American Society for Clinical Pathology, 2017. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com

Process chain modeling and selection in an additive manufacturing context

DEFF Research Database (Denmark)

Thompson, Mary Kathryn; Stolfi, Alessandro; Mischkot, Michael

2016-01-01

This paper introduces a new two-dimensional approach to modeling manufacturing process chains. This approach is used to consider the role of additive manufacturing technologies in process chains for a part with micro scale features and no internal geometry. It is shown that additive manufacturing...... evolving fields like additive manufacturing....

Environmental law and climate change : Volumes I & II

NARCIS (Netherlands)

Verschuuren, Jonathan

Two volume set that brings together 54 of the most influential and important scientific journal articles in the field of climate law, thematically grouped together as follows: introducing climate law, theories and approaches, climate change mitigation, climate change adaptation, climate justice,

Additionality of global benefits and financial additionality in the context of the AIJ negotiations

Energy Technology Data Exchange (ETDEWEB)

Puhl, I.

1996-12-31

The Conference of the Party at their first meeting (COP1) took a decision regarding criteria for joint implementation as indicated in Art. 4.2 (a) of the FCCC which established a pilot phase for activities implemented jointly (AIJ) under the pilot phase. Besides some more technical issues this decision specified that such measures should bring about real, measurable and long-term environmental benefits related to the mitigation of climate change that would not have occurred in the absence of such activities. It also established that the financing of AIJ shall be additional to the financial obligations of developed country parties. These two requirements are called the additionality criteria for AIJ. The first refers to the realness of GHG emission abatement (which means reduction compared to a baseline) whereas the second describes that funds earmarked for AIJ have no other objective (i.e. profit making, export promotion) but to reduce GHG emissions to avoid the free-riding of investors and subsequently developed country parties. The reporting framework as well as the reporting requirements under national programs do not specify further the two types of additionality and even though research focuses on issues like baseline determination there has been no attempt so far to identify approaches which contribute towards defining strict and practicable methods and guidelines to frame additionality criteria. The first FCCC assessment of pilot project reporting revealed that in the reporting of activities, emissions additionality often remained unclear, especially in cases where AIJ was only a portion of an existing or already planned project, and that there is a point about how to account for financial additionality. It subsequently proposed to develop a uniform approach to baseline determination and the assessment of emission (reduction) additionality and financial additionality.

Mechanism and kinetics of addition polymerizations

CERN Document Server

Kucera, M

1991-01-01

This volume presents an up-to-date survey of knowledge concerning addition type polymerizations. It contains nine chapters, each of which covers a particular basic term. Whenever necessary, the phenomena are discussed from the viewpoint of both stationary and non-stationary state of radical, ionic (i.e. anionic and cationic) and coordination polymerization. Special attention has been paid to the propagation process. It provides not only a general overview but also information on important special cases (theoretical conditions of propagation, influence of external factors, controlled propagatio

A review of plan library approaches in adaptive radiotherapy of bladder cancer.

Science.gov (United States)

Collins, Shane D; Leech, Michelle M

2018-05-01

Large variations in the shape and size of the bladder volume are commonly observed in bladder cancer radiotherapy (RT). The clinical target volume (CTV) is therefore frequently inadequately treated and large isotropic margins are inappropriate in terms of dose to organs at risk (OAR); thereby making adaptive radiotherapy (ART) attractive for this tumour site. There are various methods of ART delivery, however, for bladder cancer, plan libraries are frequently used. A review of published studies on plan libraries for bladder cancer using four databases (Pubmed, Science Direct, Embase and Cochrane Library) was conducted. The endpoints selected were accuracy and feasibility of initiation of a plan library strategy into a RT department. Twenty-four articles were included in this review. The majority of studies reported improvement in accuracy with 10 studies showing an improvement in planning target volume (PTV) and CTV coverage with plan libraries, some by up to 24%. Seventeen studies showed a dose reduction to OARs, particularly the small bowel V45Gy, V40Gy, V30Gy and V10Gy, and the rectal V30Gy. However, the occurrence of no suitable plan was reported in six studies, with three studies showing no significant difference between adaptive and non-adaptive strategies in terms of target coverage. In addition, inter-observer variability in plan selection appears to remain problematic. The additional resources, education and technology required for the initiation of plan library selection for bladder cancer may hinder its routine clinical implementation, with eight studies illustrating increased treatment time required. While there is a growing body of evidence in support of plan libraries for bladder RT, many studies differed in their delivery approach. The advent of the clinical use of the MRI-linear accelerator will provide RT departments with the opportunity to consider daily online adaption for bladder cancer as an alternate to plan library approaches.

Food additives and preschool children.

Science.gov (United States)

Martyn, Danika M; McNulty, Breige A; Nugent, Anne P; Gibney, Michael J

2013-02-01

Food additives have been used throughout history to perform specific functions in foods. A comprehensive framework of legislation is in place within Europe to control the use of additives in the food supply and ensure they pose no risk to human health. Further to this, exposure assessments are regularly carried out to monitor population intakes and verify that intakes are not above acceptable levels (acceptable daily intakes). Young children may have a higher dietary exposure to chemicals than adults due to a combination of rapid growth rates and distinct food intake patterns. For this reason, exposure assessments are particularly important in this age group. The paper will review the use of additives and exposure assessment methods and examine factors that affect dietary exposure by young children. One of the most widely investigated unfavourable health effects associated with food additive intake in preschool-aged children are suggested adverse behavioural effects. Research that has examined this relationship has reported a variety of responses, with many noting an increase in hyperactivity as reported by parents but not when assessed using objective examiners. This review has examined the experimental approaches used in such studies and suggests that efforts are needed to standardise objective methods of measuring behaviour in preschool children. Further to this, a more holistic approach to examining food additive intakes by preschool children is advisable, where overall exposure is considered rather than focusing solely on behavioural effects and possibly examining intakes of food additives other than food colours.

A probabilistic method for determining the volume fraction of pre-embedded capsules in self-healing materials

International Nuclear Information System (INIS)

Lv, Zhong; Chen, Huisu

2014-01-01

Autonomous healing of cracks using pre-embedded capsules containing healing agent is becoming a promising approach to restore the strength of damaged structures. In addition to the material properties, the size and volume fraction of capsules influence crack healing in the matrix. Understanding the crack and capsule interaction is critical in the development and design of structures made of self-healing materials. Assuming that the pre-embedded capsules are randomly dispersed we theoretically model flat ellipsoidal crack interaction with capsules and determine the probability of a crack intersecting the pre-embedded capsules i.e. the self-healing probability. We also develop a probabilistic model of a crack simultaneously meeting with capsules and catalyst carriers in two-component self-healing system matrix. Using a risk-based healing approach, we determine the volume fraction and size of the pre-embedded capsules that are required to achieve a certain self-healing probability. To understand the effect of the shape of the capsules on self-healing we theoretically modeled crack interaction with spherical and cylindrical capsules. We compared the results of our theoretical model with Monte-Carlo simulations of crack interaction with capsules. The formulae presented in this paper will provide guidelines for engineers working with self-healing structures in material selection and sustenance. (paper)

Weapons-grade plutonium dispositioning. Volume 1: Executive summary

International Nuclear Information System (INIS)

Parks, D.L.; Sauerbrun, T.J.

1993-06-01

The Secretary of Energy requested the National Academy of Sciences (NAS) Committee on International Security and Arms Control to evaluate dispositioning options for weapons-grade plutonium. The Idaho National Engineering Laboratory (INEL) assisted NAS in this evaluation by investigating the technical aspects of the dispositioning options and their capability for achieving plutonium annihilation levels greater than 90%. Additionally, the INEL investigated the feasibility of using plutonium fuels (without uranium) for disposal in existing light water reactors and provided a preconceptual analysis for a reactor specifically designed for destruction of weapons-grade plutonium. This four-volume report was prepared for NAS to document the findings of these studies. Volume 2 evaluates 12 plutonium dispositioning options. Volume 3 considers a concept for a low-temperature, low-pressure, low-power-density, low-coolant-flow-rate light water reactor that quickly destroys plutonium without using uranium or thorium. This reactor concept does not produce electricity and has no other mission than the destruction of plutonium. Volume 4 addresses neutronic performance, fabrication technology, and fuel performance and compatibility issues for zirconium-plutonium oxide fuels and aluminum-plutonium metallic fuels. This volumes gives summaries of Volumes 2--4

Free-volume characterization of nanostructurized substances by positron annihilation lifetime spectroscopy

Science.gov (United States)

Shpotyuk, O.; Ingram, A.; Shpotyuk, Ya.

2018-02-01

Methodological possibilities of positron annihilation lifetime (PAL) spectroscopy are examined to parameterize free-volume structural evolution processes in some nanostructurized substances obeying conversion from positronium (Ps) decaying to positron trapping. Unlike conventional x3-term fitting analysis based on admixed positron trapping and Ps decaying, the effect of nanostructurization is considered as occurring due to conversion from preferential Ps decaying in initial host matrix to positron trapping in modified (nanostructurized) host-guest matrix. The developed approach referred to as x3-x2-CDA (coupling decomposition algorithm) allows estimation defect-free bulk and defect-specific positron lifetimes of free-volume elements responsible for nanostructurization. The applicability of this approach is proved for some nanostructurized materials allowing free-volume changes through Ps-to-positron trapping conversion, such as (i) metallic Ag nanoparticles embedded in polymer matrix, (ii) structure-modification processes caused by swift heavy ions irradiation in polystyrene, and (iii) host-guest chemistry problems like water immersion in alumomagnesium spinel ceramics. This approach is considered to be used as test-indicator, separating processes of host-matrix nanostructurization due to embedded nanoparticles from uncorrelated changes in positron-trapping and Ps-decaying channels.

Nondestructive Determination of Reinforcement Volume Fractions in Particulate Composites : Ultrasonic Method

International Nuclear Information System (INIS)

Jeong, Hyun Jo

1998-01-01

A nondestructive ultrasonic technique is presented for estimating the reinforcement volume fractions of particulate composites. The proposed technique employs a theoretical model which accounts for composite microstructures, together with a measurement of ultrasonic velocity to determine the reinforcement volume fractions. The approach is used for a wide range of SiC particulate reinforced Al matrix (SiC p /AI) composites. The method is considered to be reliable in determining the reinforcement volume fractions. The technique could be adopted in a production unit for the quality assessment of the metal matrix particulate composite extrusions

The application of volume-outcome contouring in data warehousing.

Science.gov (United States)

Studnicki, James; Berndt, Donald J; Luther, Stephen L; Fisher, John W

2004-01-01

Despite a compelling body of published research on the nature of provider volume and clinical outcomes, healthcare executives and policymakers have not managed to develop and implement systems that are useful in directing patients to higher volume providers via selective referral or avoidance. A specialized data warehouse application, utilizing hospital discharge data linked to physician biographical information, allows detailed analysis of physician and hospital volume and the resulting pattern (contour) of related outcomes such as mortality, complications, and medical errors. The approach utilizes a historical repository of hospital discharge data in which the outcomes of interest, important patient characteristics and risk factors used in severity-adjusting of the outcomes are derived from the coding structure of the data.

New approach to lung cancer screening with helical volume CT

International Nuclear Information System (INIS)

Midorikawa, S.; Hashimoto, N.; Katakura, T.; Suzuki, K.

1990-01-01

This paper evaluates the relationship between reducing radiation dose to the patient and maintaining the clinical quality of the chest image in lung cancer screening by helical-volume CT (HVCT). The authors evaluated the changing relationship between radiation dose and clinical quality after changing the HVCY scanning conditions (such as stroke of patient transport and section thickness) as well as adding copper filters of various thickness and using high-voltage x-ray examination to complement CT examinations. The authors were able to reduce radiation dose by changing the HVCT scanning conditions (eg, stroke of 20 mm/sec, with a section thickness of 10 mm)

Intraoperative blood loss in bimaxillary orthognathic surgery with multisegmental Le Fort I osteotomies and additional procedures.

Science.gov (United States)

Kretschmer, W B; Baciut, G; Bacuit, Mihaela; Zoder, W; Wangerin, K

2010-06-01

Autologous blood donation is not currently recommended by most authors for routine bimaxillary osteotomies. There are few data about bimaxillary procedures with multisegmental maxillary osteotomies. Our aim was to investigate the effect of additional osteotomies and iliac crest grafts on operative blood loss. A total of 225 consecutive patients having bimaxillary multisegmental osteotomies during a three-year period (January 2006-January 2009) were examined to see if their haemoglobin concentration and packed cell volume were reduced. The influence of iliac crest grafts, additional osteotomies (genioplasty, malar osteotomy, iliac crest graft, anterior mandibular segmental osteotomy), operating time, age, and sex were assessed. Neither age nor sex influenced blood loss, whereas operating time correlated significantly with reductions in haemoglobin concentration and packed cell volume. Blood loss was significantly higher in the group who had additional procedures (p 0.001 for haemoglobin concentration and packed cell volume) than in the group who had no additional procedures, whereas there were no significant differences among the three subgroups who had additional procedures (additional osteotomies, iliac crest grafts, or both procedures). Four patients who had additional procedures required transfusion, whereas no blood was given in the group who had no additional procedures. Because the transfusion rate was so low, we could make no general recommendation for preoperative blood donation in such cases. Copyright 2009 The British Association of Oral and Maxillofacial Surgeons. Published by Elsevier Ltd. All rights reserved.

Lower Face: Clinical Anatomy and Regional Approaches with Injectable Fillers.

Science.gov (United States)

Braz, André; Humphrey, Shannon; Weinkle, Susan; Yee, G Jackie; Remington, B Kent; Lorenc, Z Paul; Yoelin, Steve; Waldorf, Heidi A; Azizzadeh, Babak; Butterwick, Kimberly J; de Maio, Mauricio; Sadick, Neil; Trevidic, Patrick; Criollo-Lamilla, Gisella; Garcia, Philippe

2015-11-01

The use of injectable fillers enables facial sculpting through treatment of volume depletion and modeling of facial contours. Injectable fillers are among the most frequently performed minimally invasive cosmetic procedures.However, treatment of the lower third of the face can be challenging and requires expertise in facial anatomy. In this article, the authors provide a comprehensive review of the anatomy of the lower third of the face, highlighting danger zones. In addition, the authors describe their preferred approach and detailed technique used in the treatment of each specific area, namely the jawline, prejowl sulcus, melomental folds, and lips.

Conferences on Combinatorial and Additive Number Theory

CERN Document Server

2014-01-01

This proceedings volume is based on papers presented at the Workshops on Combinatorial and Additive Number Theory (CANT), which were held at the Graduate Center of the City University of New York in 2011 and 2012. The goal of the workshops is to survey recent progress in combinatorial number theory and related parts of mathematics. The workshop attracts researchers and students who discuss the state-of-the-art, open problems, and future challenges in number theory.

Moderator's view: High-volume plasma exchange: pro, con and consensus.

Science.gov (United States)

Kaplan, Andre A

2017-09-01

I have been asked to comment on the pro and con opinions regarding high-volume plasma exchange. The authors of both positions have provided cogent arguments and a reasonable approach to choosing the exchange volume for any given therapeutic plasma exchange. The major issue of relevance in this discussion is the nature of the toxins targeted for removal. These parameters include molecular weight, the apparent volume of distribution, the degree of protein binding, the biologic and chemical half-life, and the severity and rapidity of its toxicity. © The Author 2017. Published by Oxford University Press on behalf of ERA-EDTA. All rights reserved.

An Approach for Patient-Specific Multi-domain Vascular Mesh Generation Featuring Spatially Varying Wall Thickness Modeling

OpenAIRE

Raut, Samarth S.; Liu, Peng; Finol, Ender A.

2015-01-01

In this work, we present a computationally efficient image-derived volume mesh generation approach for vasculatures that implements spatially varying patient-specific wall thickness with a novel inward extrusion of the wall surface mesh. Multi-domain vascular meshes with arbitrary numbers, locations, and patterns of both iliac bifurcations and thrombi can be obtained without the need to specify features or landmark points as input. In addition, the mesh output is coordinate-frame independent ...

When high-volume PCI operators in high-volume hospitals move to lower volume hospitals-Do they still maintain high volume and quality of outcomes?

Science.gov (United States)

Lu, Tsung-Hsueh; Li, Sheng-Tun; Liang, Fu-Wen; Lee, Jo-Chi; Yin, Wei-Hsian

2017-10-31

The aim of this quasi-experimental study was to examine whether high-volume percutaneous coronary intervention (PCI) operators still maintain high volume and quality of outcomes when they moved to lower volume hospitals. Systematic reviews have indicated that high-volume PCI operators and hospitals have higher quality outcomes. However, little is known on whether high PCI volume and high quality outcomes are mainly due to operator characteristics (i.e., skill and experience) and is portable across organizations or whether it is due to hospital characteristics (i.e., equipment, team, and management system) and is less portable. We used Taiwan National Health Insurance claims data 2000-2012 to identify 98 high-volume PCI operators, 10 of whom moved from one hospital to another during the study period. We compared the PCI volume, risk-adjusted mortality ratio, and major adverse cardiovascular event (MACE) ratio before and after moving. Of the 10 high-volume operators who moved, 6 moved from high- to moderate- or low-volume hospitals, with median annual PCI volumes (interquartile range) of 130 (117-165) in prior hospitals and 54 (46-84) in subsequent hospitals (the hospital the operator moved to), and the remaining 4 moved from high to high-volume hospitals, with median annual PCI volumes (interquartile range) of 151 (133-162) in prior hospitals and 193 (178-239) in subsequent hospitals. No significant differences were observed in the risk-adjusted mortality ratios and MACE ratios between high-volume operators and matched controls before and after moving. High-volume operators cannot maintain high volume when they moved from high to moderate or low-volume hospitals; however, the quality of care is maintained. High PCI volume and high-quality outcomes are less portable and more hospital bound. © 2017 Wiley Periodicals, Inc.

75 FR 39612 - Allocation of Second Additional Fiscal Year (FY) 2010 In-Quota Volume for Raw Cane Sugar

Science.gov (United States)

2010-07-09

...) 2010 In-Quota Volume for Raw Cane Sugar AGENCY: Office of the United States Trade Representative... the tariff-rate quota (TRQ) for imported raw cane sugar. DATES: Effective Date: July 9, 2010... cane and refined sugar. Section 404(d) (3) of the Uruguay Round Agreements Act (19 U.S.C. 3601(d)(3...

Measurement of the airway surface liquid volume with simple light refraction microscopy.

Science.gov (United States)

Harvey, Peter R; Tarran, Robert; Garoff, Stephen; Myerburg, Mike M

2011-09-01

In the cystic fibrosis (CF) lung, the airway surface liquid (ASL) volume is depleted, impairing mucus clearance from the lung and leading to chronic airway infection and obstruction. Several therapeutics have been developed that aim to restore normal airway surface hydration to the CF airway, yet preclinical evaluation of these agents is hindered by the paucity of methods available to directly measure the ASL. Therefore, we sought to develop a straightforward approach to measure the ASL volume that would serve as the basis for a standardized method to assess mucosal hydration using readily available resources. Primary human bronchial epithelial (HBE) cells cultured at an air-liquid interface develop a liquid meniscus at the edge of the culture. We hypothesized that the size of the fluid meniscus is determined by the ASL volume, and could be measured as an index of the epithelial surface hydration status. A simple method was developed to measure the volume of fluid present in meniscus by imaging the refraction of light at the ASL interface with the culture wall using low-magnification microscopy. Using this method, we found that primary CF HBE cells had a reduced ASL volume compared with non-CF HBE cells, and that known modulators of ASL volume caused the predicted responses. Thus, we have demonstrated that this method can detect physiologically relevant changes in the ASL volume, and propose that this novel approach may be used to rapidly assess the effects of airway hydration therapies in high-throughput screening assays.

Effects of Anti-VEGF on Predicted Antibody Biodistribution: Roles of Vascular Volume, Interstitial Volume, and Blood Flow

Science.gov (United States)

Boswell, C. Andrew; Ferl, Gregory Z.; Mundo, Eduardo E.; Bumbaca, Daniela; Schweiger, Michelle G.; Theil, Frank-Peter; Fielder, Paul J.; Khawli, Leslie A.

2011-01-01

Background The identification of clinically meaningful and predictive models of disposition kinetics for cancer therapeutics is an ongoing pursuit in drug development. In particular, the growing interest in preclinical evaluation of anti-angiogenic agents alone or in combination with other drugs requires a complete understanding of the associated physiological consequences. Methodology/Principal Findings Technescan™ PYP™, a clinically utilized radiopharmaceutical, was used to measure tissue vascular volumes in beige nude mice that were naïve or administered a single intravenous bolus dose of a murine anti-vascular endothelial growth factor (anti-VEGF) antibody (10 mg/kg) 24 h prior to assay. Anti-VEGF had no significant effect (p>0.05) on the fractional vascular volumes of any tissues studied; these findings were further supported by single photon emission computed tomographic imaging. In addition, apart from a borderline significant increase (p = 0.048) in mean hepatic blood flow, no significant anti-VEGF-induced differences were observed (p>0.05) in two additional physiological parameters, interstitial fluid volume and the organ blood flow rate, measured using indium-111-pentetate and rubidium-86 chloride, respectively. Areas under the concentration-time curves generated by a physiologically-based pharmacokinetic model changed substantially (>25%) in several tissues when model parameters describing compartmental volumes and blood flow rates were switched from literature to our experimentally derived values. However, negligible changes in predicted tissue exposure were observed when comparing simulations based on parameters measured in naïve versus anti-VEGF-administered mice. Conclusions/Significance These observations may foster an enhanced understanding of anti-VEGF effects in murine tissues and, in particular, may be useful in modeling antibody uptake alone or in combination with anti-VEGF. PMID:21436893

Satellite Power Systems (SPS) concept definition study. Volume 6: SPS technology requirements and verification

Science.gov (United States)

Hanley, G.

1978-01-01

Volume 6 of the SPS Concept Definition Study is presented and also incorporates results of NASA/MSFC in-house effort. This volume includes a supporting research and technology summary. Other volumes of the final report that provide additional detail are as follows: (1) Executive Summary; (2) SPS System Requirements; (3) SPS Concept Evolution; (4) SPS Point Design Definition; (5) Transportation and Operations Analysis; and Volume 7, SPS Program Plan and Economic Analysis.

Workshop Report on Additive Manufacturing for Large-Scale Metal Components - Development and Deployment of Metal Big-Area-Additive-Manufacturing (Large-Scale Metals AM) System

Energy Technology Data Exchange (ETDEWEB)

Babu, Sudarsanam Suresh [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States). Manufacturing Demonstration Facility; Love, Lonnie J. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States). Manufacturing Demonstration Facility; Peter, William H. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States). Manufacturing Demonstration Facility; Dehoff, Ryan [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States). Manufacturing Demonstration Facility

2016-05-01

Additive manufacturing (AM) is considered an emerging technology that is expected to transform the way industry can make low-volume, high value complex structures. This disruptive technology promises to replace legacy manufacturing methods for the fabrication of existing components in addition to bringing new innovation for new components with increased functional and mechanical properties. This report outlines the outcome of a workshop on large-scale metal additive manufacturing held at Oak Ridge National Laboratory (ORNL) on March 11, 2016. The charter for the workshop was outlined by the Department of Energy (DOE) Advanced Manufacturing Office program manager. The status and impact of the Big Area Additive Manufacturing (BAAM) for polymer matrix composites was presented as the background motivation for the workshop. Following, the extension of underlying technology to low-cost metals was proposed with the following goals: (i) High deposition rates (approaching 100 lbs/h); (ii) Low cost (<$10/lbs) for steel, iron, aluminum, nickel, as well as, higher cost titanium, (iii) large components (major axis greater than 6 ft) and (iv) compliance of property requirements. The above concept was discussed in depth by representatives from different industrial sectors including welding, metal fabrication machinery, energy, construction, aerospace and heavy manufacturing. In addition, DOE’s newly launched High Performance Computing for Manufacturing (HPC4MFG) program was reviewed. This program will apply thermo-mechanical models to elucidate deeper understanding of the interactions between design, process, and materials during additive manufacturing. Following these presentations, all the attendees took part in a brainstorming session where everyone identified the top 10 challenges in large-scale metal AM from their own perspective. The feedback was analyzed and grouped in different categories including, (i) CAD to PART software, (ii) selection of energy source, (iii

Use of additive material to stabilize the soil swelling

Science.gov (United States)

Parsaee, B.; Estabragh, A. R.; Bordbar, A. T.; Eskandari, G. H.

2009-04-01

Change volume increasing of soil, because of increase in its humidity content causes appearing of swelling phenomenon in the soil. This phenomenon has created a lot of damages in the building which is constructed on this kind of soils. Usage the additive materials which stabilize the swelling, has been the subject of many researches. In this research the Potential expansibility of the expansive soils, which were stabilized by additive materials such as Lime, cement and coal ash, was investigated. To get this purpose, by preparing soil samples mixed with upper additive material, changes of potential swelling of stabilized soils were compared. The results revealed that usage of these stabilizing materials caused the decrease in destructive effects due to swelling of soils to some extent. Keywords: swelling, soil stabilizing, additive material, coal ash

[Definition of nodal volumes in breast cancer treatment and segmentation guidelines].

Science.gov (United States)

Kirova, Y M; Castro Pena, P; Dendale, R; Campana, F; Bollet, M A; Fournier-Bidoz, N; Fourquet, A

2009-06-01

To assist in the determination of breast and nodal volumes in the setting of radiotherapy for breast cancer and establish segmentation guidelines. Materials and methods. Contrast metarial enhanced CT examinations were obtained in the treatment position in 25 patients to clearly define the target volumes. The clinical target volume (CTV) including the breast, internal mammary nodes, supraclavicular and subclavicular regions and axxilary region were segmented along with the brachial plexus and interpectoral nodes. The following critical organs were also segmented: heart, lungs, contralateral breast, thyroid, esophagus and humeral head. A correlation between clinical and imaging findings and meeting between radiation oncologists and breast specialists resulted in a better definition of irradiation volumes for breast and nodes with establishement of segmentation guidelines and creation of an anatomical atlas. A practical approach, based on anatomical criteria, is proposed to assist in the segmentation of breast and node volumes in the setting of breast cancer treatment along with a definition of irradiation volumes.

Interactive Dynamic Volume Illumination with Refraction and Caustics.

Science.gov (United States)

Magnus, Jens G; Bruckner, Stefan

2018-01-01

In recent years, significant progress has been made in developing high-quality interactive methods for realistic volume illumination. However, refraction - despite being an important aspect of light propagation in participating media - has so far only received little attention. In this paper, we present a novel approach for refractive volume illumination including caustics capable of interactive frame rates. By interleaving light and viewing ray propagation, our technique avoids memory-intensive storage of illumination information and does not require any precomputation. It is fully dynamic and all parameters such as light position and transfer function can be modified interactively without a performance penalty.

FDG-PET imaging for the assessment of physiologic volume response during radiotherapy in cervix cancer

International Nuclear Information System (INIS)

Lin, Lilie L.; Yang Zhiyun; Mutic, Sasa; Miller, Tom R.; Grigsby, Perry W.

2006-01-01

Purpose: To evaluate the physiologic tumor volume response during treatment in cervical cancer using 18F-fluorodeoxyglucose positron emission tomography (FDG-PET). Patients and Methods: This was a prospective study of 32 patients. Physiologic tumor volume in cubic centimeters was determined from the FDG-PET images using the 40% threshold method. Results: The mean pretreatment tumor volume was 102 cm 3 . The mean volume by clinical Stages I, II, and III were 54, 79, and 176 cm 3 , respectively. After 19.8 Gy external irradiation to the pelvis, the reduction in tumor volume was 29% (72 cm 3 ). An additional 13 Gy from high-dose-rate (HDR) brachytherapy reduced the mean volume to 15.4 cm 3 , and this was subsequently reduced to 8.6 cm 3 with 13 Gy additional HDR brachytherapy (26 Gy, HDR). Four patients had physiologic FDG uptake in the cervix at 3 months after the completion of therapy. The mean time to the 50% reduction in physiologic tumor volume was 19.9 days and after combined external irradiation and HDR to 24.9 Gy. Conclusion: These results indicate that physiologic tumor volume determination by FDG-PET is feasible and that a 50% physiologic tumor volume reduction occurs within 20 days of starting therapy

A voxel-based technique to estimate the volume of trees from terrestrial laser scanner data

Science.gov (United States)

Bienert, A.; Hess, C.; Maas, H.-G.; von Oheimb, G.

2014-06-01

The precise determination of the volume of standing trees is very important for ecological and economical considerations in forestry. If terrestrial laser scanner data are available, a simple approach for volume determination is given by allocating points into a voxel structure and subsequently counting the filled voxels. Generally, this method will overestimate the volume. The paper presents an improved algorithm to estimate the wood volume of trees using a voxel-based method which will correct for the overestimation. After voxel space transformation, each voxel which contains points is reduced to the volume of its surrounding bounding box. In a next step, occluded (inner stem) voxels are identified by a neighbourhood analysis sweeping in the X and Y direction of each filled voxel. Finally, the wood volume of the tree is composed by the sum of the bounding box volumes of the outer voxels and the volume of all occluded inner voxels. Scan data sets from several young Norway maple trees (Acer platanoides) were used to analyse the algorithm. Therefore, the scanned trees as well as their representing point clouds were separated in different components (stem, branches) to make a meaningful comparison. Two reference measurements were performed for validation: A direct wood volume measurement by placing the tree components into a water tank, and a frustum calculation of small trunk segments by measuring the radii along the trunk. Overall, the results show slightly underestimated volumes (-0.3% for a probe of 13 trees) with a RMSE of 11.6% for the individual tree volume calculated with the new approach.

Factors controlling volume errors through 2D gully erosion assessment: guidelines for optimal survey design

Science.gov (United States)

Castillo, Carlos; Pérez, Rafael

2017-04-01

The assessment of gully erosion volumes is essential for the quantification of soil losses derived from this relevant degradation process. Traditionally, 2D and 3D approaches has been applied for this purpose (Casalí et al., 2006). Although innovative 3D approaches have recently been proposed for gully volume quantification, a renewed interest can be found in literature regarding the useful information that cross-section analysis still provides in gully erosion research. Moreover, the application of methods based on 2D approaches can be the most cost-effective approach in many situations such as preliminary studies with low accuracy requirements or surveys under time or budget constraints. The main aim of this work is to examine the key factors controlling volume error variability in 2D gully assessment by means of a stochastic experiment involving a Monte Carlo analysis over synthetic gully profiles in order to 1) contribute to a better understanding of the drivers and magnitude of gully erosion 2D-surveys uncertainty and 2) provide guidelines for optimal survey designs. Owing to the stochastic properties of error generation in 2D volume assessment, a statistical approach was followed to generate a large and significant set of gully reach configurations to evaluate quantitatively the influence of the main factors controlling the uncertainty of the volume assessment. For this purpose, a simulation algorithm in Matlab® code was written, involving the following stages: - Generation of synthetic gully area profiles with different degrees of complexity (characterized by the cross-section variability) - Simulation of field measurements characterised by a survey intensity and the precision of the measurement method - Quantification of the volume error uncertainty as a function of the key factors In this communication we will present the relationships between volume error and the studied factors and propose guidelines for 2D field surveys based on the minimal survey

Sensitivity Analysis of Wavelet Neural Network Model for Short-Term Traffic Volume Prediction

Directory of Open Access Journals (Sweden)

Jinxing Shen

2013-01-01

Full Text Available In order to achieve a more accurate and robust traffic volume prediction model, the sensitivity of wavelet neural network model (WNNM is analyzed in this study. Based on real loop detector data which is provided by traffic police detachment of Maanshan, WNNM is discussed with different numbers of input neurons, different number of hidden neurons, and traffic volume for different time intervals. The test results show that the performance of WNNM depends heavily on network parameters and time interval of traffic volume. In addition, the WNNM with 4 input neurons and 6 hidden neurons is the optimal predictor with more accuracy, stability, and adaptability. At the same time, a much better prediction record will be achieved with the time interval of traffic volume are 15 minutes. In addition, the optimized WNNM is compared with the widely used back-propagation neural network (BPNN. The comparison results indicated that WNNM produce much lower values of MAE, MAPE, and VAPE than BPNN, which proves that WNNM performs better on short-term traffic volume prediction.

Extraction and LOD control of colored interval volumes

Science.gov (United States)

Miyamura, Hiroko N.; Takeshima, Yuriko; Fujishiro, Issei; Saito, Takafumi

2005-03-01

Interval volume serves as a generalized isosurface and represents a three-dimensional subvolume for which the associated scalar filed values lie within a user-specified closed interval. In general, it is not an easy task for novices to specify the scalar field interval corresponding to their ROIs. In order to extract interval volumes from which desirable geometric features can be mined effectively, we propose a suggestive technique which extracts interval volumes automatically based on the global examination of the field contrast structure. Also proposed here is a simplification scheme for decimating resultant triangle patches to realize efficient transmission and rendition of large-scale interval volumes. Color distributions as well as geometric features are taken into account to select best edges to be collapsed. In addition, when a user wants to selectively display and analyze the original dataset, the simplified dataset is restructured to the original quality. Several simulated and acquired datasets are used to demonstrate the effectiveness of the present methods.

Path integral for stochastic inflation: Nonperturbative volume weighting, complex histories, initial conditions, and the end of inflation

Science.gov (United States)

Gratton, Steven

2011-09-01

In this paper we present a path integral formulation of stochastic inflation. Volume weighting can be naturally implemented from this new perspective in a very straightforward way when compared to conventional Langevin approaches. With an in-depth study of inflation in a quartic potential, we investigate how the inflaton evolves and how inflation typically ends both with and without volume weighting. The calculation can be carried to times beyond those accessible to conventional Fokker-Planck approaches. Perhaps unexpectedly, complex histories sometimes emerge with volume weighting. The reward for this excursion into the complex plane is an insight into how volume-weighted inflation both loses memory of initial conditions and ends via slow roll. The slow-roll end of inflation mitigates certain “Youngness Paradox”-type criticisms of the volume-weighted paradigm. Thus it is perhaps time to rehabilitate proper-time volume weighting as a viable measure for answering at least some interesting cosmological questions.

Path integral for stochastic inflation: Nonperturbative volume weighting, complex histories, initial conditions, and the end of inflation

International Nuclear Information System (INIS)

Gratton, Steven

2011-01-01

In this paper we present a path integral formulation of stochastic inflation. Volume weighting can be naturally implemented from this new perspective in a very straightforward way when compared to conventional Langevin approaches. With an in-depth study of inflation in a quartic potential, we investigate how the inflaton evolves and how inflation typically ends both with and without volume weighting. The calculation can be carried to times beyond those accessible to conventional Fokker-Planck approaches. Perhaps unexpectedly, complex histories sometimes emerge with volume weighting. The reward for this excursion into the complex plane is an insight into how volume-weighted inflation both loses memory of initial conditions and ends via slow roll. The slow-roll end of inflation mitigates certain ''Youngness Paradox''-type criticisms of the volume-weighted paradigm. Thus it is perhaps time to rehabilitate proper-time volume weighting as a viable measure for answering at least some interesting cosmological questions.

Effects of addition of different fibers on rheological characteristics of cake batter and quality of cakes.

Science.gov (United States)

Aydogdu, Ayca; Sumnu, Gulum; Sahin, Serpil

2018-02-01

The aim of this study was to investigate the effects of addition of dietary fibers on rheological properties of batter and cake quality. Wheat flour was replaced by 5 and 10% (wt%) oat, pea, apple and lemon fibers. All cake batters showed shear thinning behavior. Incorporation of fibers increased consistency index (k), storage modulus (G') and loss modulus (G″). As quality parameters, specific volume, hardness, weight loss, color and microstructure of cakes were investigated. Cakes containing oat and pea fibers (5%) had similar specific volume and texture with control cakes which contained no fiber. As fiber concentration increased, specific volume decreased but hardness increased. No significant difference was found between weight loss of control cake and cakes with oat, pea and apple fibers. Lemon fiber enriched cakes had the lowest specific volume, weight loss and color difference. When microstructural images were examined, it was seen that control cake had more porous structure than fiber enriched cakes. In addition, lemon and apple fiber containing cakes had less porous crumb structure as compared to oat and pea containing ones. Oat and pea fiber (5%) enriched cakes had similar physical properties (volume, texture and color) with control cakes.

Frontal and temporal volumes in Childhood Absence Epilepsy.

Science.gov (United States)

Caplan, Rochelle; Levitt, Jennifer; Siddarth, Prabha; Wu, Keng Nei; Gurbani, Suresh; Sankar, Raman; Shields, W Donald

2009-11-01

This study compared frontotemporal brain volumes in children with childhood absence epilepsy (CAE) to age- and gender-matched children without epilepsy. It also examined the association of these volumes with seizure, demographic, perinatal, intelligence quotient (IQ), and psychopathology variables. Twenty-six children with CAE, aged 7.5-11.8 years, and 37 children without epilepsy underwent brain magnetic resonance imaging (MRI) scans at 1.5 Tesla. Tissue was segmented, and total brain, frontal lobe, frontal parcellations, and temporal lobe volumes were computed. All children had IQ testing and structured psychiatric interviews. Parents provided seizure, perinatal, and behavioral information on each child. The CAE group had significantly smaller gray matter volumes of the left orbital frontal gyrus as well as both left and right temporal lobes compared to the age- and gender-matched children without epilepsy. In the CAE group these volumes were related to age, gender, ethnicity, and pregnancy complications but not to seizure, IQ, and psychopathology variables. In the group of children without epilepsy, however, the volumes were related to IQ. These findings suggest that CAE impacts brain development in regions implicated in behavior, cognition, and language. In addition to supporting the cortical focus theory of CAE, these findings also imply that CAE is not a benign disorder.

Cortisol, Cytokines, and Hippocampal Volume in the Elderly

Directory of Open Access Journals (Sweden)

Keith Daniel Sudheimer

2014-07-01

Full Text Available Separate bodies of literature report that elevated pro-inflammatory cytokines and cortisol negatively affect hippocampal structure and cognitive functioning, particularly in older adults. Although interactions between cytokines and cortisol occur through a variety of known mechanisms, few studies consider how their interactions affect brain structure. In this preliminary study, we assess the impact of interactions between circulating levels of IL-1Beta, IL-6, IL-8, IL-10, IL-12, TNF-alpha, and waking cortisol on hippocampal volume. Twenty-eight community-dwelling older adults underwent blood draws for quantification of circulating cytokines and saliva collections to quantify the cortisol awakening response. Hippocampal volume measurements were made using structural magnetic resonance imaging. Elevated levels of waking cortisol in conjunction with higher concentrations of IL-6 and TNF-alpha were associated with smaller hippocampal volumes. In addition, independent of cortisol, higher levels of IL-1beta and TNF-alpha were also associated with smaller hippocampal volumes. These data provide preliminary evidence that higher cortisol, in conjunction with higher IL-6 and TNF-alpha, are associated with smaller hippocampal volume in older adults. We suggest that the dynamic balance between the hypothalamic-pituitary adrenal axis and inflammation processes may explain hippocampal volume reductions in older adults better than either set of measures do in isolation.

Thermodynamic volume and the extended Smarr relation

Energy Technology Data Exchange (ETDEWEB)

Hyun, Seungjoon; Jeong, Jaehoon; Park, Sang-A; Yi, Sang-Heon [Department of Physics, College of Science, Yonsei University,Seoul 120-749 (Korea, Republic of)

2017-04-10

We continue to explore the scaling transformation in the reduced action formalism of gravity models. As an extension of our construction, we consider the extended forms of the Smarr relation for various black holes, adopting the cosmological constant as the bulk pressure as in some literatures on black holes. Firstly, by using the quasi-local formalism for charges, we show that, in a general theory of gravity, the volume in the black hole thermodynamics could be defined as the thermodynamic conjugate variable to the bulk pressure in such a way that the first law can be extended consistently. This, so called, thermodynamic volume can be expressed explicitly in terms of the metric and field variables. Then, by using the scaling transformation allowed in the reduced action formulation, we obtain the extended Smarr relation involving the bulk pressure and the thermodynamic volume. In our approach, we do not resort to Euler’s homogeneous scaling of charges while incorporating the would-be hairy contribution without any difficulty.

Melting metal waste for volume reduction and decontamination

International Nuclear Information System (INIS)

Copeland, G.L.; Heshmatpour, B.; Heestand, R.L.

1980-01-01

Melt-slagging was investigated as a technique for volume reduction and decontamination of radioactively contaminated scrap metals. Experiments were conducted using several metals and slags in which the partitioning of the contaminant U or Pu to the slag was measured. Concentrations of U or Pu in the metal product of about 1 ppM were achieved for many metals. A volume reduction of 30:1 was achieved for a typical batch of mixed metal scrap. Additionally, the production of granular products was demonstrated with metal shot and crushed slag

Reactive Additive Stabilization Process (RASP) for hazardous and mixed waste vitrification

International Nuclear Information System (INIS)

Jantzen, C.M.; Pickett, J.B.; Ramsey, W.G.

1993-01-01

Solidification of hazardous/mixed wastes into glass is being examined at the Savannah River Site (SRS) for (1) nickel plating line (F006) sludges and (2) incinerator wastes. Vitrification of these wastes using high surface area additives, the Reactive Additive Stabilization Process (RASP), has been determined to greatly enhance the dissolution and retention of hazardous, mixed, and heavy metal species in glass. RASP lowers melt temperatures (typically 1050-- 1150 degrees C), thereby minimizing volatility concerns during vitrification. RASP maximizes waste loading (typically 50--75 wt% on a dry oxide basis) by taking advantage of the glass forming potential of the waste. RASP vitrification thereby minimizes waste disposal volume (typically 86--97 vol. %), and maximizes cost savings. Solidification of the F006 plating line sludges containing depleted uranium has been achieved in both soda-lime-silica (SLS) and borosilicate glasses at 1150 degrees C up to waste loadings of 75 wt%. Solidification of incinerator blowdown and mixtures of incinerator blowdown and bottom kiln ash have been achieved in SLS glass at 1150 degrees C up to waste loadings of 50% using RASP. These waste loadings correspond to volume reductions of 86 and 94 volume %, respectively, with large associated savings in storage costs

RELAP5/MOD3 code manual. Volume 4, Models and correlations

International Nuclear Information System (INIS)

1995-08-01

The RELAP5 code has been developed for best-estimate transient simulation of light water reactor coolant systems during postulated accidents. The code models the coupled behavior of the reactor coolant system and the core for loss-of-coolant accidents and operational transients such as anticipated transient without scram, loss of offsite power, loss of feedwater, and loss of flow. A generic modeling approach is used that permits simulating a variety of thermal hydraulic systems. Control system and secondary system components are included to permit modeling of plant controls, turbines, condensers, and secondary feedwater systems. RELAP5/MOD3 code documentation is divided into seven volumes: Volume I presents modeling theory and associated numerical schemes; Volume II details instructions for code application and input data preparation; Volume III presents the results of developmental assessment cases that demonstrate and verify the models used in the code; Volume IV discusses in detail RELAP5 models and correlations; Volume V presents guidelines that have evolved over the past several years through the use of the RELAP5 code; Volume VI discusses the numerical scheme used in RELAP5; and Volume VII presents a collection of independent assessment calculations

Total volume versus bouts

DEFF Research Database (Denmark)

Chinapaw, Mai; Klakk, Heidi; Møller, Niels Christian

2018-01-01

BACKGROUND/OBJECTIVES: Examine the prospective relationship of total volume versus bouts of sedentary behaviour (SB) and moderate-to-vigorous physical activity (MVPA) with cardiometabolic risk in children. In addition, the moderating effects of weight status and MVPA were explored. SUBJECTS....../METHODS: Longitudinal study including 454 primary school children (mean age 10.3 years). Total volume and bouts (i.e. ≥10 min consecutive minutes) of MVPA and SB were assessed by accelerometry in Nov 2009/Jan 2010 (T1) and Aug/Oct 2010 (T2). Triglycerides, total cholesterol/HDL cholesterol ratio (TC:HDLC ratio......, with or without mutual adjustments between MVPA and SB. The moderating effects of weight status and MVPA (for SB only) were examined by adding interaction terms. RESULTS: Children engaged daily in about 60 min of total MVPA and 0-15 min/week in MVPA bouts. Mean total sedentary time was around 7 h/day with over 3...

OCCUPATIONAL EDUCATION--PLANNING AND PROGRAMMING. VOLUME TWO.

Science.gov (United States)

KOTZ, ARNOLD

ADDITIONAL POSITION PAPERS BASED ON INFORMATION GATHERED IN THE RECONNAISSANCE SURVEYS OF PLANNING AND PROGRAMING IN OCCUPATIONAL EDUCATION, REPORTED IN VOLUME ONE (VT 005 041), ARE PRESENTED. PART IV, CONCERNED WITH PROGRAM STRUCTURE AND BUDGETING AND THEIR RELATION TO THE PLANNING PROCESS, INCLUDES THE PAPERS--(1) "CURRENT POLICIES AND…

European cement conference and exhibition. Proceedings volume

Energy Technology Data Exchange (ETDEWEB)

McCaffrey, R. (ed.)

2004-07-01

Topics covered various aspects of the European cement industry including trends, market, emissions trading, environment, state-of-the-art technology, kilns and dedusting solutions. Two papers have been abstracted separately. A CD-ROM of the conference papers, including additional papers not in the printed volume, is also available.

MANAJEMEN KULTUR ROTIFER DENGAN TANGKI VOLUME KECIL

Directory of Open Access Journals (Sweden)

Philip Teguh Imanto

2009-04-01

applied differently among three trials. First trial without seawater addition, increasing volume of culture media was only from 15 L. of N. occulata within 5 days culture, second trial was done with addition of seawater of 40 L and 40 L of N. occulata every day; and the last trial with twice dosage of baker yeast from trial I and II. The result showed that the average total production from the first trial was 122.37 x 106 ind. rotifer and the second trial was decreased to 97.67 x 106 ind. rotifer. Highest average total production was achieved by the last trial with 187.17 x 106 ind. rotifer per culture tank 500 L. Culture management on the third trial gave the best result with the lowest deviation among replication tanks, and proved as the best management practice for small-scale culture container.

Improved approach to quantitative cardiac volumetrics using automatic thresholding and manual trimming: a cardiovascular MRI study.

Science.gov (United States)

Rayarao, Geetha; Biederman, Robert W W; Williams, Ronald B; Yamrozik, June A; Lombardi, Richard; Doyle, Mark

2018-01-01

To establish the clinical validity and accuracy of automatic thresholding and manual trimming (ATMT) by comparing the method with the conventional contouring method for in vivo cardiac volume measurements. CMR was performed on 40 subjects (30 patients and 10 controls) using steady-state free precession cine sequences with slices oriented in the short-axis and acquired contiguously from base to apex. Left ventricular (LV) volumes, end-diastolic volume, end-systolic volume, and stroke volume (SV) were obtained with ATMT and with the conventional contouring method. Additionally, SV was measured independently using CMR phase velocity mapping (PVM) of the aorta for validation. Three methods of calculating SV were compared by applying Bland-Altman analysis. The Bland-Altman standard deviation of variation (SD) and offset bias for LV SV for the three sets of data were: ATMT-PVM (7.65, [Formula: see text]), ATMT-contours (7.85, [Formula: see text]), and contour-PVM (11.01, 4.97), respectively. Equating the observed range to the error contribution of each approach, the error magnitude of ATMT:PVM:contours was in the ratio 1:2.4:2.5. Use of ATMT for measuring ventricular volumes accommodates trabeculae and papillary structures more intuitively than contemporary contouring methods. This results in lower variation when analyzing cardiac structure and function and consequently improved accuracy in assessing chamber volumes.

Comparison of different homogenization approaches for elastic–viscoplastic materials

International Nuclear Information System (INIS)

Mercier, S; Molinari, A; Berbenni, S; Berveiller, M

2012-01-01

Homogenization of linear viscoelastic and non-linear viscoplastic composite materials is considered in this paper. First, we compare two homogenization schemes based on the Mori–Tanaka method coupled with the additive interaction (AI) law proposed by Molinari et al (1997 Mech. Mater. 26 43–62) or coupled with a concentration law based on translated fields (TF) originally proposed for the self-consistent scheme by Paquin et al (1999 Arch. Appl. Mech. 69 14–35). These methods are also evaluated against (i) full-field calculations of the literature based on the finite element method and on fast Fourier transform, (ii) available analytical exact solutions obtained in linear viscoelasticity and (iii) homogenization methods based on variational approaches. Developments of the AI model are obtained for linear and non-linear material responses while results for the TF method are shown for the linear case. Various configurations are considered: spherical inclusions, aligned fibers, hard and soft inclusions, large material contrasts between phases, volume-preserving versus dilatant anelastic flow, non-monotonic loading. The agreement between the AI and TF methods is excellent and the correlation with full field calculations is in general of quite good quality (with some exceptions for non-linear composites with a large volume fraction of very soft inclusions for which a discrepancy of about 15% was found for macroscopic stress). Description of the material behavior with internal variables can be accounted for with the AI and TF approaches and therefore complex loadings can be easily handled in contrast with most hereditary approaches. (paper)

Lamb Wave Assessment of Fiber Volume Fraction in Composites

Science.gov (United States)

Seale, Michael D.; Smith, Barry T.; Prosser, W. H.; Zalameda, Joseph N.

1998-01-01

Among the various techniques available, ultrasonic Lamb waves offer a convenient method of examining composite materials. Since the Lamb wave velocity depends on the elastic properties of a material, an effective tool exists to evaluate composites by measuring the velocity of these waves. Lamb waves can propagate over long distances and are sensitive to the desired in-plane elastic properties of the material. This paper discusses a study in which Lamb waves were used to examine fiber volume fraction variations of approximately 0.40-0.70 in composites. The Lamb wave measurements were compared to fiber volume fractions obtained from acid digestion tests. Additionally, a model to predict the fiber volume fraction from Lamb wave velocity values was evaluated.

Cellwise conservative unsplit advection for the volume of fluid method

DEFF Research Database (Denmark)

Comminal, Raphaël; Spangenberg, Jon; Hattel, Jesper Henri

2015-01-01

We present a cellwise conservative unsplit (CCU) advection scheme for the volume of fluid method (VOF) in 2D. Contrary to other schemes based on explicit calculations of the flux balances, the CCU advection adopts a cellwise approach where the pre-images of the control volumes are traced......-overlapping donating regions and pre-images with conforming edges to their neighbors, resulting in the conservativeness and the boundedness (liquid volume fraction inside the interval [0, 1]) of the CCU advection scheme. Finally, the update of the liquid volume fractions is computed from the intersections of the pre......-image polygons with the reconstructed interfaces. The CCU scheme is tested on several benchmark tests for the VOF advection, together with the standard piecewise linear interface calculation (PLIC). The geometrical errors of the CCU compare favorably with other unsplit VOF-PLIC schemes. Finally, potential...

Exploring the connectome: Petascale volume visualization of microscopy data streams

KAUST Repository

Beyer, Johanna; Hadwiger, Markus; Al-Awami, Ali K.; Jeong, Wonki; Kasthuri, Narayanan; Lichtman, Jeff W M D; Pfister, Hanspeter

2013-01-01

Recent advances in high-resolution microscopy let neuroscientists acquire neural-tissue volume data of extremely large sizes. However, the tremendous resolution and the high complexity of neural structures present big challenges to storage, processing, and visualization at interactive rates. A proposed system provides interactive exploration of petascale (petavoxel) volumes resulting from high-throughput electron microscopy data streams. The system can concurrently handle multiple volumes and can support the simultaneous visualization of high-resolution voxel segmentation data. Its visualization-driven design restricts most computations to a small subset of the data. It employs a multiresolution virtual-memory architecture for better scalability than previous approaches and for handling incomplete data. Researchers have employed it for a 1-teravoxel mouse cortex volume, of which several hundred axons and dendrites as well as synapses have been segmented and labeled. © 1981-2012 IEEE.

Exploring the connectome: Petascale volume visualization of microscopy data streams

KAUST Repository

Beyer, Johanna

2013-07-01

Recent advances in high-resolution microscopy let neuroscientists acquire neural-tissue volume data of extremely large sizes. However, the tremendous resolution and the high complexity of neural structures present big challenges to storage, processing, and visualization at interactive rates. A proposed system provides interactive exploration of petascale (petavoxel) volumes resulting from high-throughput electron microscopy data streams. The system can concurrently handle multiple volumes and can support the simultaneous visualization of high-resolution voxel segmentation data. Its visualization-driven design restricts most computations to a small subset of the data. It employs a multiresolution virtual-memory architecture for better scalability than previous approaches and for handling incomplete data. Researchers have employed it for a 1-teravoxel mouse cortex volume, of which several hundred axons and dendrites as well as synapses have been segmented and labeled. © 1981-2012 IEEE.

A concept of volume rendering guided search process to analyze medical data set.

Science.gov (United States)

Zhou, Jianlong; Xiao, Chun; Wang, Zhiyan; Takatsuka, Masahiro

2008-03-01

This paper firstly presents an approach of parallel coordinates based parameter control panel (PCP). The PCP is used to control parameters of focal region-based volume rendering (FRVR) during data analysis. It uses a parallel coordinates style interface. Different rendering parameters represented with nodes on each axis, and renditions based on related parameters are connected using polylines to show dependencies between renditions and parameters. Based on the PCP, a concept of volume rendering guided search process is proposed. The search pipeline is divided into four phases. Different parameters of FRVR are recorded and modulated in the PCP during search phases. The concept shows that volume visualization could play the role of guiding a search process in the rendition space to help users to efficiently find local structures of interest. The usability of the proposed approach is evaluated to show its effectiveness.

Characterization of strain rate sensitivity and activation volume using the indentation relaxation test

International Nuclear Information System (INIS)

Xu Baoxing; Chen Xi; Yue Zhufeng

2010-01-01

We present the possibility of extracting the strain rate sensitivity, activation volume and Helmholtz free energy (for dislocation activation) using just one indentation stress relaxation test, and the approach is demonstrated with polycrystalline copper. The Helmholtz free energy measured from indentation relaxation agrees well with that from the conventional compression relaxation test, which validates the proposed approach. From the indentation relaxation test, the measured indentation strain rate sensitivity exponent is found to be slightly larger, and the indentation activation volume much smaller, than their counterparts from the compression test. The results indicate the involvement of multiple dislocation mechanisms in the indentation test.

Experimental approaches and applications

CERN Document Server

Crasemann, Bernd

1975-01-01

Atomic Inner-Shell Processes, Volume II: Experimental Approaches and Applications focuses on the physics of atomic inner shells, with emphasis on experimental aspects including the use of radioactive atoms for studies of atomic transition probabilities. Surveys of modern techniques of electron and photon spectrometry are also presented, and selected practical applications of inner-shell processes are outlined. Comprised of six chapters, this volume begins with an overview of the general principles underlying the experimental techniques that make use of radioactive isotopes for inner-sh

Management of Diabetes Associated with Nephrotic Syndrome: Therapeutic Potential of Dapagliflozin for Protracted Volume Retention

Directory of Open Access Journals (Sweden)

Toshimi Imai

2015-01-01

Full Text Available A 48-year-old female was admitted to our hospital presenting with a chief complaint of progressive swelling because of diabetic nephrotic syndrome. Dapagliflozin seemed to play a role in accelerating the patient's urinary sodium excretion as well as reducing gross fluid retention despite the fact that her nephrotic condition was resistant to furosemide. Our experience emphasizes a potential novel approach to overcoming loop diuretic resistance using this agent among some subsets of type 2 diabetic subjects complicated with severe volume accumulation. We believe that combination treatment consisting of dapagliflozin and furosemide may produce diuretic synergy via sequential nephron blockade. The accumulation of more experience with additional cases similar to ours requires continuous and careful attention.

Free volume from positron lifetime and pressure-volume-temperature experiments in relation to structural relaxation of van der Waals molecular glass-forming liquids.

Science.gov (United States)

Dlubek, G; Shaikh, M Q; Rätzke, K; Paluch, M; Faupel, F

2010-06-16

Positron annihilation lifetime spectroscopy (PALS) is employed to characterize the temperature dependence of the free volume in two van der Waals liquids: 1, 1'-bis(p-methoxyphenyl)cyclohexane (BMPC) and 1, 1'-di(4-methoxy-5-methylphenyl)cyclohexane (BMMPC). From the PALS spectra analysed with the routine LifeTime9.0, the size (volume) distribution of local free volumes (subnanometer size holes), its mean, [v(h)], and mean dispersion, σ(h), were calculated. A comparison with the macroscopic volume from pressure-volume-temperature (PV T) experiments delivered the hole density and the specific hole free volume and a complete characterization of the free volume microstructure in that sense. These data are used in correlation with structural (α) relaxation data from broad-band dielectric spectroscopy (BDS) in terms of the Cohen-Grest and Cohen-Turnbull free volume models. An extension of the latter model allows us to quantify deviations between experiments and theory and an attempt to systematize these in terms of T(g) or of the fragility. The experimental data for several fragile and less fragile glass formers are involved in the final discussion. It was concluded that, for large differences in the fragility of different glass formers, the positron lifetime mirrors clearly the different character of these materials. For small differences in the fragility, additional properties like the character of bonds and chemical structure of the material may affect size, distribution and thermal behaviour of the free volume.

Free volume from positron lifetime and pressure-volume-temperature experiments in relation to structural relaxation of van der Waals molecular glass-forming liquids

Energy Technology Data Exchange (ETDEWEB)

Dlubek, G [ITA Institute for Innovative Technologies, Koethen/Halle, Wiesenring 4, D-06120 Lieskau (Germany); Shaikh, M Q; Raetzke, K; Faupel, F [Faculty of Engineering, Institute for Materials Science, Christian-Albrechts University of Kiel, Kaiserstrasse 2, D-24143 Kiel (Germany); Paluch, M, E-mail: guenter.dlubek@gmx.d [Institute of Physics, Silesian University, Uniwersytecka 4, 40-007 Katowice (Poland)

2010-06-16

Positron annihilation lifetime spectroscopy (PALS) is employed to characterize the temperature dependence of the free volume in two van der Waals liquids: 1, 1'-bis(p-methoxyphenyl)cyclohexane (BMPC) and 1, 1'-di(4-methoxy-5-methylphenyl)cyclohexane (BMMPC). From the PALS spectra analysed with the routine LifeTime9.0, the size (volume) distribution of local free volumes (subnanometer size holes), its mean, (v{sub h}), and mean dispersion, {sigma}{sub h}, were calculated. A comparison with the macroscopic volume from pressure-volume-temperature (PV T) experiments delivered the hole density and the specific hole free volume and a complete characterization of the free volume microstructure in that sense. These data are used in correlation with structural ({alpha}) relaxation data from broad-band dielectric spectroscopy (BDS) in terms of the Cohen-Grest and Cohen-Turnbull free volume models. An extension of the latter model allows us to quantify deviations between experiments and theory and an attempt to systematize these in terms of T{sub g} or of the fragility. The experimental data for several fragile and less fragile glass formers are involved in the final discussion. It was concluded that, for large differences in the fragility of different glass formers, the positron lifetime mirrors clearly the different character of these materials. For small differences in the fragility, additional properties like the character of bonds and chemical structure of the material may affect size, distribution and thermal behaviour of the free volume.

Altitude Acclimatization and Blood Volume: Effects of Exogenous Erythrocyte Volume Expansion

National Research Council Canada - National Science Library

Sawka, M

1996-01-01

...: (a) altitude acclimatization effects on erythrocyte volume and plasma volume; (b) if exogenous erythrocyte volume expansion alters subsequent erythrocyte volume and plasma volume adaptations; (c...

Water volume reduction increases eutrophication risk in tropical semi-arid reservoirs

Directory of Open Access Journals (Sweden)

Carlos Alberto Nascimento da Rocha Junior

2018-04-01

Full Text Available Abstract Aim Global patterns of temperature and precipitation have significantly changed over the last century and nearly all predictions point to even greater changes by the end of 2100. Long periods of drought in semi-arid regions generally reduce reservoirs and lakes water level, increasing the nutrients concentrations in the water. Our principal hypothesis is that water volume reduction, driven by prolonged droughts, will increase reservoirs susceptibility to eutrophication and accordingly an increase in trophic state. To test this hypothesis, we used a comparative analysis of ecosystems in a space-for-time substitution approach, in a Brazilian semi-arid region, to predict the consequences of reservoirs water volume reduction on key limnological variables. Methods We sampled 16 reservoirs located in two sub-basins with contrasting rainfall regimes, inserted on Piranhas-Açu watershed. The Seridó River basin (SB is dry and the Piancó River basin (SB is humid, with annual mean precipitation of 500 and 700 mm, respectively. Linear regressions analyzes were performed to assess whether the percentage of maximum volume stored (%MVS is a good predictor for total phosphorus (TP, total nitrogen (TN and chlorophyll-a (CHLA. In addition, a two factorial analysis of variance (two-way ANOVA was performed to test for period (dry, very dry and extremely dry, basin (SB and PB and their interactions effects on TP, TN, CHLA, conductivity, turbidity, and Secchi depth. Results The results showed a reduction in the reservoirs %MVS both for PB and SB regions. At the extremely dry period, all reservoirs were classified as eutrophic, but TP concentrations reached much higher values in SB than in PB. The linear regressions analyses showed that the TP and TN were negatively related to %MVS during all periods sampled. The two-way ANOVA showed that there were significant basin and period effects on TP, TN, Secchi depth and turbidity, whereas for CHLA and conductivity

A study of Channeling, Volume Reflection and Volume Capture of 3.35 - 14.0 GeV Electrons in a bent Silicon Crystal

Energy Technology Data Exchange (ETDEWEB)

Wistisen, T. N. [Aarhus Univ. (Denmark); Uggerhoj, U. I. [Aarhus Univ. (Denmark); Wienands, U. [SLAC National Accelerator Lab., Menlo Park, CA (United States); Markiewicz, T. W. [SLAC National Accelerator Lab., Menlo Park, CA (United States); Noble, R. J. [SLAC National Accelerator Lab., Menlo Park, CA (United States); Benson, B. L. [SLAC National Accelerator Lab., Menlo Park, CA (United States); Smith, T. [SLAC National Accelerator Lab., Menlo Park, CA (United States); Bagli, E. [Univ. of Ferrara (Italy); Bandiera, L. [Univ. of Ferrara (Italy); Germogli, G. [Univ. of Ferrara (Italy); Guidi, V. [Univ. of Ferrara (Italy); Mazzolari, A. [Univ. of Ferrara (Italy); Holtzapple, R. [California Polytechnic State Univ. (CalPoly), San Luis Obispo, CA (United States); Tucker, S. [California Polytechnic State Univ. (CalPoly), San Luis Obispo, CA (United States)

2015-12-03

We present the experimental data and analysis of experiments conducted at SLAC National Accelerator Laboratory investigating the processes of channeling, volume-reflection and volume-capture along the (111) plane in a strongly bent quasi-mosaic silicon crystal. Additionally, these phenomena were investigated at 5 energies: 3.35, 4.2, 6.3, 10.5 and 14.0 GeV with a crystal with bending radius of 0.15m, corresponding to curvatures of 0.070, 0.088, 0.13, 0.22 and 0.29 times the critical curvature respectively. We have extracted important parameters describing the channeling process such as the dechanneling length, the angle of volume reflection, the surface transmission and the widths of the distribution of channeled particles parallel and orthogonal to the plane.

Evaluation of Additive Manufacturing for Composite Part Molds

Energy Technology Data Exchange (ETDEWEB)

Duty, Chad E. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Springfield, Robert M. [Tru Design, LLC, Knoxville, TN (United States)

2015-02-01

The ORNL Manufacturing Demonstration Facility (MDF) collaborated with Tru-Design to test the quality and durability of molds used for making fiber reinforced composites using additive manufacturing. The partners developed surface treatment techniques including epoxy coatings and machining to improve the quality of the surface finish. Test samples made using the printed and surface finished molds demonstrated life spans suitable for one-of-a-kind and low-volume applications, meeting the project objective.

Infill Optimization for Additive Manufacturing - Approaching Bone-like Porous Structures

DEFF Research Database (Denmark)

Wu, Jun; Aage, Niels; Westermann, Ruediger

2018-01-01

Porous structures such as trabecular bone are widely seen in nature. These structures exhibit superior mechanical properties whilst being lightweight. In this paper, we present a method to generate bone-like porous structures asl ightweight infill for additive manufacturing. Our method builds upon...

Iterative volume morphing and learning for mobile tumor based on 4DCT.

Science.gov (United States)

Mao, Songan; Wu, Huanmei; Sandison, George; Fang, Shiaofen

2017-02-21

During image-guided cancer radiation treatment, three-dimensional (3D) tumor volumetric information is important for treatment success. However, it is typically not feasible to image a patient's 3D tumor continuously in real time during treatment due to concern over excessive patient radiation dose. We present a new iterative morphing algorithm to predict the real-time 3D tumor volume based on time-resolved computed tomography (4DCT) acquired before treatment. An offline iterative learning process has been designed to derive a target volumetric deformation function from one breathing phase to another. Real-time volumetric prediction is performed to derive the target 3D volume during treatment delivery. The proposed iterative deformable approach for tumor volume morphing and prediction based on 4DCT is innovative because it makes three major contributions: (1) a novel approach to landmark selection on 3D tumor surfaces using a minimum bounding box; (2) an iterative morphing algorithm to generate the 3D tumor volume using mapped landmarks; and (3) an online tumor volume prediction strategy based on previously trained deformation functions utilizing 4DCT. The experimental performance showed that the maximum morphing deviations are 0.27% and 1.25% for original patient data and artificially generated data, which is promising. This newly developed algorithm and implementation will have important applications for treatment planning, dose calculation and treatment validation in cancer radiation treatment.

Enabling lightweight designs by a new laser based approach for joining aluminum to steel

Science.gov (United States)

Brockmann, Rüdiger; Kaufmann, Sebastian; Kirchhoff, Marc; Candel-Ruiz, Antonio; Müllerschön, Oliver; Havrilla, David

2015-03-01

As sustainability is an essential requirement, lightweight design becomes more and more important, especially for mobility. Reduced weight ensures more efficient vehicles and enables better environmental impact. Besides the design, new materials and material combinations are one major trend to achieve the required weight savings. The use of Carbon Fiber Reinforced Plastics (abbr. CFRP) is widely discussed, but so far high volume applications are rarely to be found. This is mainly due to the fact that parts made of CFRP are much more expensive than conventional parts. Furthermore, the proper technologies for high volume production are not yet ready. Another material with a large potential for lightweight design is aluminum. In comparison to CFRP, aluminum alloys are generally more affordable. As aluminum is a metallic material, production technologies for high volume standard cutting or joining applications are already developed. In addition, bending and deep-drawing can be applied. In automotive engineering, hybrid structures such as combining high-strength steels with lightweight aluminum alloys retain significant weight reduction but also have an advantage over monolithic aluminum - enhanced behavior in case of crash. Therefore, since the use of steel for applications requiring high mechanical properties is unavoidable, methods for joining aluminum with steel parts have to be further developed. Former studies showed that the use of a laser beam can be a possibility to join aluminum to steel parts. In this sense, the laser welding process represents a major challenge, since both materials have different thermal expansion coefficients and properties related to the behavior in corrosive media. Additionally, brittle intermetallic phases are formed during welding. A promising approach to welding aluminum to steel is based on the use of Laser Metal Deposition (abbr. LMD) with deposit materials in the form of powders. Within the present work, the advantages of this

Just-in-Time Training for High-Risk Low-Volume Therapies: An Approach to Ensure Patient Safety.

Science.gov (United States)

Helman, Stephanie; Lisanti, Amy Jo; Adams, Ann; Field, Cynthia; Davis, Katherine Finn

2016-01-01

High-risk low-volume therapies are those therapies that are practiced infrequently and yet carry an increased risk to patients because of their complexity. Staff nurses are required to competently manage these therapies to treat patients' unique needs and optimize outcomes; however, maintaining competence is challenging. This article describes implementation of Just-in-Time Training, which requires validation of minimum competency of bedside nurses managing high-risk low-volume therapies through direct observation of a return-demonstration competency checklist.

40 CFR 80.599 - How do I calculate volume balances for designation purposes?

Science.gov (United States)

2010-07-01

... (CONTINUED) AIR PROGRAMS (CONTINUED) REGULATION OF FUELS AND FUEL ADDITIVES Motor Vehicle Diesel Fuel... June 30, 2013. July 1, 2013 May 31, 2014. (2) [Reserved] (b) Volume balance for motor vehicle diesel fuel. (1) A facility's motor vehicle diesel fuel volume balance is calculated as follows: MVB = MVI−MVO...

Volume Ray Casting with Peak Finding and Differential Sampling

KAUST Repository

Knoll, A.; Hijazi, Y.; Westerteiger, R.; Schott, M.; Hansen, C.; Hagen, H.

2009-01-01

classification. In this paper, we introduce a method for rendering such features by explicitly solving for isovalues within the volume rendering integral. In addition, we present a sampling strategy inspired by ray differentials that automatically matches

Cooperative rearranging region size and free volume in As-Se glasses

Energy Technology Data Exchange (ETDEWEB)

Saiter, A; Saiter, J-M [Laboratoire PBM, UMR 6522, LECAP, Institut des Materiaux de Rouen, Universite de Rouen, Faculte des Sciences, Avenue de l' Universite BP 12, 76801 Saint Etienne du Rouvray (France); Golovchak, R; Shpotyuk, M; Shpotyuk, O [Lviv Scientific Research Institute of Materials of SRC ' Carat' , 202, Stryjska street, Lviv, UA-79031 (Ukraine)

2009-02-18

Glasses of the As-Se system have been used as model objects of the covalent disordered inorganic polymers to investigate the correlation between the cooperative rearranging region (CRR) size determined at the glass transition temperature and the free volume fraction in the glassy state. The CRR size has been determined using temperature modulated differential scanning calorimetry data according to Donth's approach, while the free volume fraction in the investigated materials has been estimated using positron annihilation lifetime spectroscopy data. The obtained results testify that the appearance of open-volume defects greater than 80 A{sup 3} leads to a significant decrease in the CRR size.

Cooperative rearranging region size and free volume in As-Se glasses

International Nuclear Information System (INIS)

Saiter, A; Saiter, J-M; Golovchak, R; Shpotyuk, M; Shpotyuk, O

2009-01-01

Glasses of the As-Se system have been used as model objects of the covalent disordered inorganic polymers to investigate the correlation between the cooperative rearranging region (CRR) size determined at the glass transition temperature and the free volume fraction in the glassy state. The CRR size has been determined using temperature modulated differential scanning calorimetry data according to Donth's approach, while the free volume fraction in the investigated materials has been estimated using positron annihilation lifetime spectroscopy data. The obtained results testify that the appearance of open-volume defects greater than 80 A 3 leads to a significant decrease in the CRR size.

Big Cat Coalitions: A Comparative Analysis of Regional Brain Volumes in Felidae.

Science.gov (United States)

Sakai, Sharleen T; Arsznov, Bradley M; Hristova, Ani E; Yoon, Elise J; Lundrigan, Barbara L

2016-01-01

Broad-based species comparisons across mammalian orders suggest a number of factors that might influence the evolution of large brains. However, the relationship between these factors and total and regional brain size remains unclear. This study investigated the relationship between relative brain size and regional brain volumes and sociality in 13 felid species in hopes of revealing relationships that are not detected in more inclusive comparative studies. In addition, a more detailed analysis was conducted of four focal species: lions ( Panthera leo ), leopards ( Panthera pardus ), cougars ( Puma concolor ), and cheetahs ( Acinonyx jubatus ). These species differ markedly in sociality and behavioral flexibility, factors hypothesized to contribute to increased relative brain size and/or frontal cortex size. Lions are the only truly social species, living in prides. Although cheetahs are largely solitary, males often form small groups. Both leopards and cougars are solitary. Of the four species, leopards exhibit the most behavioral flexibility, readily adapting to changing circumstances. Regional brain volumes were analyzed using computed tomography. Skulls ( n = 75) were scanned to create three-dimensional virtual endocasts, and regional brain volumes were measured using either sulcal or bony landmarks obtained from the endocasts or skulls. Phylogenetic least squares regression analyses found that sociality does not correspond with larger relative brain size in these species. However, the sociality/solitary variable significantly predicted anterior cerebrum (AC) volume, a region that includes frontal cortex. This latter finding is despite the fact that the two social species in our sample, lions and cheetahs, possess the largest and smallest relative AC volumes, respectively. Additionally, an ANOVA comparing regional brain volumes in four focal species revealed that lions and leopards, while not significantly different from one another, have relatively larger AC

Big Cat Coalitions: A comparative analysis of regional brain volumes in Felidae

Directory of Open Access Journals (Sweden)

Sharleen T Sakai

2016-10-01

Full Text Available Broad-based species comparisons across mammalian orders suggest a number of factors that might influence the evolution of large brains. However, the relationship between these factors and total and regional brain size remains unclear. This study investigated the relationship between relative brain size and regional brain volumes and sociality in 13 felid species in hopes of revealing relationships that are not detected in more inclusive comparative studies. In addition, a more detailed analysis was conducted of 4 focal species: lions (Panthera leo, leopards (Panthera pardus, cougars (Puma concolor, and cheetahs (Acinonyx jubatus. These species differ markedly in sociality and behavioral flexibility, factors hypothesized to contribute to increased relative brain size and/or frontal cortex size. Lions are the only truly social species, living in prides. Although cheetahs are largely solitary, males often form small groups. Both leopards and cougars are solitary. Of the four species, leopards exhibit the most behavioral flexibility, readily adapting to changing circumstances. Regional brain volumes were analyzed using computed tomography (CT. Skulls (n=75 were scanned to create three-dimensional virtual endocasts, and regional brain volumes were measured using either sulcal or bony landmarks obtained from the endocasts or skulls. Phylogenetic least squares (PGLS regression analyses found that sociality does not correspond with larger relative brain size in these species. However, the sociality/solitary variable significantly predicted anterior cerebrum (AC volume, a region that includes frontal cortex. This latter finding is despite the fact that the two social species in our sample, lions and cheetahs, possess the largest and smallest relative AC volumes, respectively. Additionally, an ANOVA comparing regional brain volumes in 4 focal species revealed that lions and leopards, while not significantly different from one another, have relatively

Real-time 3-dimensional fetal echocardiography with an instantaneous volume-rendered display: early description and pictorial essay.

Science.gov (United States)

Sklansky, Mark S; DeVore, Greggory R; Wong, Pierre C

2004-02-01

Random fetal motion, rapid fetal heart rates, and cumbersome processing algorithms have limited reconstructive approaches to 3-dimensional fetal cardiac imaging. Given the recent development of real-time, instantaneous volume-rendered sonographic displays of volume data, we sought to apply this technology to fetal cardiac imaging. We obtained 1 to 6 volume data sets on each of 30 fetal hearts referred for formal fetal echocardiography. Each volume data set was acquired over 2 to 8 seconds and stored on the system's hard drive. Rendered images were subsequently processed to optimize translucency, smoothing, and orientation and cropped to reveal "surgeon's eye views" of clinically relevant anatomic structures. Qualitative comparison was made with conventional fetal echocardiography for each subject. Volume-rendered displays identified all major abnormalities but failed to identify small ventricular septal defects in 2 patients. Important planes and views not visualized during the actual scans were generated with minimal processing of rendered image displays. Volume-rendered displays tended to have slightly inferior image quality compared with conventional 2-dimensional images. Real-time 3-dimensional echocardiography with instantaneous volume-rendered displays of the fetal heart represents a new approach to fetal cardiac imaging with tremendous clinical potential.

Fracture criterion for brittle materials based on statistical cells of finite volume

International Nuclear Information System (INIS)

Cords, H.; Kleist, G.; Zimmermann, R.

1986-06-01

An analytical consideration of the Weibull Statistical Analysis of brittle materials established the necessity of including one additional material constant for a more comprehensive description of the failure behaviour. The Weibull analysis is restricted to infinitesimal volume elements in consequence of the differential calculus applied. It was found that infinitesimally small elements are in conflict with the basic statistical assumption and that the differential calculus is not needed in fact since nowadays most of the stress analyses are based on finite element calculations, and these are most suitable for a subsequent statistical analysis of strength. The size of a finite statistical cell has been introduced as the third material parameter. It should represent the minimum volume containing all statistical features of the material such as distribution of pores, flaws and grains. The new approach also contains a unique treatment of failure under multiaxial stresses. The quantity responsible for failure under multiaxial stresses is introduced as a modified strain energy. Sixteen different tensile specimens including CT-specimens have been investigated experimentally and analyzed with the probabilistic fracture criterion. As a result it can be stated that the failure rates of all types of specimens made from three different grades of graphite are predictable. The accuracy of the prediction is one standard deviation. (orig.) [de

An operator calculus for surface and volume modeling

Science.gov (United States)

Gordon, W. J.

1984-01-01

The mathematical techniques which form the foundation for most of the surface and volume modeling techniques used in practice are briefly described. An outline of what may be termed an operator calculus for the approximation and interpolation of functions of more than one independent variable is presented. By considering the linear operators associated with bivariate and multivariate interpolation/approximation schemes, it is shown how they can be compounded by operator multiplication and Boolean addition to obtain a distributive lattice of approximation operators. It is then demonstrated via specific examples how this operator calculus leads to practical techniques for sculptured surface and volume modeling.

DOE standard: Integration of environment, safety, and health into facility disposition activities. Volume 2: Appendices

Energy Technology Data Exchange (ETDEWEB)

NONE

1998-05-01

This volume contains the appendices that provide additional environment, safety, and health (ES and H) information to complement Volume 1 of this Standard. Appendix A provides a set of candidate DOE ES and H directives and external regulations, organized by hazard types that may be used to identify potentially applicable directives to a specific facility disposition activity. Appendix B offers examples and lessons learned that illustrate implementation of ES and H approaches discussed in Section 3 of Volume 1. Appendix C contains ISMS performance expectations to guide a project team in developing and implementing an effective ISMS and in developing specific performance criteria for use in facility disposition. Appendix D provides guidance for identifying potential Applicable or Relevant and Appropriate Requirements (ARARs) when decommissioning facilities fall under the Comprehensive Environmental Response, Compensation, Liability Act (CERCLA) process. Appendix E discusses ES and H considerations for dispositioning facilities by privatization. Appendix F is an overview of the WSS process. Appendix G provides a copy of two DOE Office of Nuclear Safety Policy and Standards memoranda that form the bases for some of the guidance discussed within the Standard. Appendix H gives information on available hazard analysis techniques and references. Appendix I provides a supplemental discussion to Sections 3.3.4, Hazard Baseline Documentation, and 3.3.6, Environmental Permits. Appendix J presents a sample readiness evaluation checklist.

DOE standard: Integration of environment, safety, and health into facility disposition activities. Volume 2: Appendices

International Nuclear Information System (INIS)

1998-05-01

This volume contains the appendices that provide additional environment, safety, and health (ES and H) information to complement Volume 1 of this Standard. Appendix A provides a set of candidate DOE ES and H directives and external regulations, organized by hazard types that may be used to identify potentially applicable directives to a specific facility disposition activity. Appendix B offers examples and lessons learned that illustrate implementation of ES and H approaches discussed in Section 3 of Volume 1. Appendix C contains ISMS performance expectations to guide a project team in developing and implementing an effective ISMS and in developing specific performance criteria for use in facility disposition. Appendix D provides guidance for identifying potential Applicable or Relevant and Appropriate Requirements (ARARs) when decommissioning facilities fall under the Comprehensive Environmental Response, Compensation, Liability Act (CERCLA) process. Appendix E discusses ES and H considerations for dispositioning facilities by privatization. Appendix F is an overview of the WSS process. Appendix G provides a copy of two DOE Office of Nuclear Safety Policy and Standards memoranda that form the bases for some of the guidance discussed within the Standard. Appendix H gives information on available hazard analysis techniques and references. Appendix I provides a supplemental discussion to Sections 3.3.4, Hazard Baseline Documentation, and 3.3.6, Environmental Permits. Appendix J presents a sample readiness evaluation checklist

1995 Solid Waste 30-year volume summary

International Nuclear Information System (INIS)

Valero, O.J.; DeForest, T.J.; Templeton, K.J.

1995-06-01

This document, prepared by Pacific Northwest Laboratory (PNL) under the direction of Westinghouse Hanford Company (WHC), provides a description of the annual low-level mixed waste (LLMW) and transuranic/transuranic mixed solid waste (TRU-TRUM) volumes expected to be managed by Hanford's Solid Waste Central Waste Complex (CWC) over the next 30 years. The waste generation sources and waste categories are also described. This document is intended to be used as a reference for short- and long-term planning of the Hanford treatment, storage, and disposal (TSD) activities over the next several decades. By estimating the waste volumes that will be generated in the future, facility planners can determine the timing of key waste management activities, evaluate alternative treatment strategies, and plan storage and disposal capacities. In addition, this document can be used by other waste sites and the general public to gain a better understanding of the types and volumes of waste that will be managed at Hanford

1995 Solid Waste 30-year volume summary

Energy Technology Data Exchange (ETDEWEB)

Valero, O.J. [Westinghouse Hanford Co., Richland, WA (United States); DeForest, T.J.; Templeton, K.J. [Pacific Northwest Lab., Richland, WA (United States)

1995-06-01

This document, prepared by Pacific Northwest Laboratory (PNL) under the direction of Westinghouse Hanford Company (WHC), provides a description of the annual low-level mixed waste (LLMW) and transuranic/transuranic mixed solid waste (TRU-TRUM) volumes expected to be managed by Hanford`s Solid Waste Central Waste Complex (CWC) over the next 30 years. The waste generation sources and waste categories are also described. This document is intended to be used as a reference for short- and long-term planning of the Hanford treatment, storage, and disposal (TSD) activities over the next several decades. By estimating the waste volumes that will be generated in the future, facility planners can determine the timing of key waste management activities, evaluate alternative treatment strategies, and plan storage and disposal capacities. In addition, this document can be used by other waste sites and the general public to gain a better understanding of the types and volumes of waste that will be managed at Hanford.

Sparse PDF Volumes for Consistent Multi-Resolution Volume Rendering

KAUST Repository

Sicat, Ronell Barrera

2014-12-31

This paper presents a new multi-resolution volume representation called sparse pdf volumes, which enables consistent multi-resolution volume rendering based on probability density functions (pdfs) of voxel neighborhoods. These pdfs are defined in the 4D domain jointly comprising the 3D volume and its 1D intensity range. Crucially, the computation of sparse pdf volumes exploits data coherence in 4D, resulting in a sparse representation with surprisingly low storage requirements. At run time, we dynamically apply transfer functions to the pdfs using simple and fast convolutions. Whereas standard low-pass filtering and down-sampling incur visible differences between resolution levels, the use of pdfs facilitates consistent results independent of the resolution level used. We describe the efficient out-of-core computation of large-scale sparse pdf volumes, using a novel iterative simplification procedure of a mixture of 4D Gaussians. Finally, our data structure is optimized to facilitate interactive multi-resolution volume rendering on GPUs.

Parallel simulation of two-phase incompressible and immiscible flows in porous media using a finite volume formulation and a modified IMPES approach

International Nuclear Information System (INIS)

Da Silva, R S; De Carvalho, D K E; Antunes, A R E; Lyra, P R M; Willmersdorf, R B

2010-01-01

In this paper a finite volume method with a 'Modified Implicit Pressure, Explicit Saturation' (MIMPES) approach is used to model the 3-D incompressible and immiscible two-phase flow of water and oil in heterogeneous and anisotropic porous media. A vertex centered finite volume method with an edge-based data structure is adopted to discretize both the elliptic pressure and the hyperbolic saturation equations using parallel computers with distributed memory. Due to the explicit solution of the saturation equation in the IMPES method, severe time step restrictions are imposed on the simulation. In order to circumvent this problem, an edge-based implementation of the MIMPES method was used. In this method, the pressure equation is solved and the velocity field is computed much less frequently than the saturation field. Following the work of Hurtado, a mean relative variation of the velocity field throughout the simulation is used to automatically control the updating process, allowing for much larger time-steps in a very simple way. In order to run large scale problems, we have developed a parallel implementation using clusters of PC's. The simulator uses open source parallel libraries like FMDB, ParMetis and PETSc. Results of speed-up and efficiency are presented to validate the performance of the parallel simulator.

Measurement of absolute left ventricular volume by radionuclide angiography: a technical review

International Nuclear Information System (INIS)

Al-Khawaja, I.M.; Lahiri, Avijit; Raftery, E.B.; Medical Research Council, Harrow

1988-01-01

Absolute left ventricular volumes have important clinical implications in the evaluation of cardiac performance. Several invasive and noninvasive techniques have been reported, none of which can be considered ideal for this purpose. Contrast angiography, echocardiography and radionuclide ventriculography are open to criticism. Different radioisotopic approaches are described with emphasis on the importance of accurate separation of left ventricular activity, the selection of background activity, and the correction for photon attenuation by body tissues. Improper use of statistics and validation techniques have obscured the value of these techniques. In the absence of a 'gold standard' there should be a 'radioisotopic' left ventricular volume with established independent characteristics, repeatability and reproducibility by which new approaches can be judged. (author)

Sparse PDF Volumes for Consistent Multi-Resolution Volume Rendering

KAUST Repository

Sicat, Ronell Barrera; Kruger, Jens; Moller, Torsten; Hadwiger, Markus

2014-01-01

This paper presents a new multi-resolution volume representation called sparse pdf volumes, which enables consistent multi-resolution volume rendering based on probability density functions (pdfs) of voxel neighborhoods. These pdfs are defined

Acid-base titrations by stepwise addition of equal volumes of titrant with special reference to automatic titrations-III Presentation of a fully automatic titration apparatus and of results supporting the theories given in the preceding parts.

Science.gov (United States)

Pehrsson, L; Ingman, F

1977-02-01

This paper forms Part III of a series in which the first two parts describe methods for evaluating titrations performed by stepwise addition of equal volumes of titrant. The great advantage of these methods is that they do not require an accurate calibration of the electrode system. This property makes the methods very suitable for routine work. e.g., in automatic analysis. An apparatus for performing such titrations automatically is presented. Further, results of titrations of monoprotic acids, a diprotic acid, an ampholyte, a mixture of an acid with its conjugate base, and mixtures of two acids with a small difference between the stability constants are given. Most of these titrations cannot be evaluated by the Gran or Hofstee methods but yield results having errors of the order of 0.1% if the methods proposed in Parts I and II of this series are employed. The advantages of the method of stepwise addition of equal volumes of titrant combined with the proposed evaluation methods, in comparison with common methods such as titration to a preset pH, are that all the data are used in the evaluation, permitting a statistical treatment and giving better possibilities for tracing systematic errors.

Immersive volume rendering of blood vessels

Science.gov (United States)

Long, Gregory; Kim, Han Suk; Marsden, Alison; Bazilevs, Yuri; Schulze, Jürgen P.

2012-03-01

In this paper, we present a novel method of visualizing flow in blood vessels. Our approach reads unstructured tetrahedral data, resamples it, and uses slice based 3D texture volume rendering. Due to the sparse structure of blood vessels, we utilize an octree to efficiently store the resampled data by discarding empty regions of the volume. We use animation to convey time series data, wireframe surface to give structure, and utilize the StarCAVE, a 3D virtual reality environment, to add a fully immersive element to the visualization. Our tool has great value in interdisciplinary work, helping scientists collaborate with clinicians, by improving the understanding of blood flow simulations. Full immersion in the flow field allows for a more intuitive understanding of the flow phenomena, and can be a great help to medical experts for treatment planning.

The influence of additional fluors on the retention ability of dough and the technological quality of bakery products

Directory of Open Access Journals (Sweden)

Tatiana Bojňanská

2015-08-01

Full Text Available The work monitored rheofermentation properties of dough prepared from composite flours formed by 70% of wheat flour T650 and the addition of 30%. Three kinds of additions were used, namely spelt flour, amaranth flour and buckwheat flour. To determine rheofermentation properties Rheofermentometer Rhea F4 was used, by means of which the dough development, the production of fermentation gases, retention ability of dough and the activity of used baking yeast were analysed. The best ability to retain formed fermentation gas had wheat flour (control and composite flour with the addition of spelt flour. The composite flour with addition of amaranth flour showed a retention coefficient compared to the control lower by 13%, and the composite flour with addition of buckwheat flour showed a retention coefficient compared to the control reduced by 20%. Control flour and composite flours were then processed in the baking experiment. Based on its results it was possible to evaluate the effect of the addition and retention capacity of dough on the quality of the final products (experimental loaves. The biggest loaf volume (200 cm3 and the optimal vaulting (0.65 were found in the control and a loaf made of composite flour with addition of spelt. Loaf volume, produced from composite flours with the addition of amaranth, and buckwheat was compared to control lower by 18.7%, and 16.3% respectively. The value of vaulting of these products (0.40 can be evaluated as unsatisfactory. Based on the evaluation of results observed by measuring on the rheofermentometer and baking experiment results it can be concluded that a better ability to retain the formed fermentation gas, thus ensuring high volume, had loaves made from wheat flour T650 and composite flour with addition of spelt flour. Based on the findings, it is possible to state that the results of rheofermentometric measurements predict the volume and vaulting of bakery products. By means of Rheofermentometer

Damage evolution and failure mechanisms in additively manufactured stainless steel

Energy Technology Data Exchange (ETDEWEB)

Carlton, Holly D., E-mail: carlton4@llnl.gov [Materials Engineering Division, Lawrence Livermore National Laboratory, 7000 East Avenue, Livermore, CA 94550 (United States); Haboub, Abdel [Lincoln University, Life and Physical Sciences Department, 820 Chestnut St, Jefferson City, MO 65101 (United States); Gallegos, Gilbert F. [Materials Engineering Division, Lawrence Livermore National Laboratory, 7000 East Avenue, Livermore, CA 94550 (United States); Parkinson, Dilworth Y.; MacDowell, Alastair A. [Advanced Light Source, Lawrence Berkeley National Laboratory, 1 Cyclotron Road, Berkeley, CA 94720 (United States)

2016-01-10

In situ tensile tests were performed on additively manufactured austenitic stainless steel to track damage evolution within the material. For these experiments Synchrotron Radiation micro-Tomography was used to measure three-dimensional pore volume, distribution, and morphology in stainless steel at the micrometer length-scale while tensile loading was applied. The results showed that porosity distribution played a larger role in affecting the fracture mechanisms than measured bulk density. Specifically, additively manufactured stainless steel specimens with large inhomogeneous void distributions displayed a flaw-dominated failure where cracks were shown to initiate at pre-existing voids, while annealed additively manufactured stainless steel specimens, which contained low porosity and randomly distributed pores, displayed fracture mechanisms that closely resembled wrought metal.

Exploring a Multiphysics Resolution Approach for Additive Manufacturing

Science.gov (United States)

Estupinan Donoso, Alvaro Antonio; Peters, Bernhard

2018-06-01

Metal additive manufacturing (AM) is a fast-evolving technology aiming to efficiently produce complex parts while saving resources. Worldwide, active research is being performed to solve the existing challenges of this growing technique. Constant computational advances have enabled multiscale and multiphysics numerical tools that complement the traditional physical experimentation. In this contribution, an advanced discrete-continuous concept is proposed to address the physical phenomena involved during laser powder bed fusion. The concept treats powder as discrete by the extended discrete element method, which predicts the thermodynamic state and phase change for each particle. The fluid surrounding is solved with multiphase computational fluid dynamics techniques to determine momentum, heat, gas and liquid transfer. Thus, results track the positions and thermochemical history of individual particles in conjunction with the prevailing fluid phases' temperature and composition. It is believed that this methodology can be employed to complement experimental research by analysis of the comprehensive results, which can be extracted from it to enable AM processes optimization for parts qualification.

Neutron guide geometries for homogeneous phase space volume transformation

Energy Technology Data Exchange (ETDEWEB)

Stüßer, N., E-mail: stuesser@helmholtz-berlin.de; Bartkowiak, M.; Hofmann, T.

2014-06-01

We extend geometries for recently developed optical guide systems that perform homogeneous phase space volume transformations on neutron beams. These modules allow rotating beam directions and can simultaneously compress or expand the beam cross-section. Guide systems combining these modules offer the possibility to optimize ballistic guides with and without direct view on the source and beam splitters. All systems are designed for monochromatic beams with a given divergence. The case of multispectral beams with wavelength-dependent divergence distributions is addressed as well. - Highlights: • Form invariant volume transformation in phase space. • Geometrical approach. • Ballistic guide, beam splitter, beam bender.

Neutron guide geometries for homogeneous phase space volume transformation

International Nuclear Information System (INIS)

Stüßer, N.; Bartkowiak, M.; Hofmann, T.

2014-01-01

We extend geometries for recently developed optical guide systems that perform homogeneous phase space volume transformations on neutron beams. These modules allow rotating beam directions and can simultaneously compress or expand the beam cross-section. Guide systems combining these modules offer the possibility to optimize ballistic guides with and without direct view on the source and beam splitters. All systems are designed for monochromatic beams with a given divergence. The case of multispectral beams with wavelength-dependent divergence distributions is addressed as well. - Highlights: • Form invariant volume transformation in phase space. • Geometrical approach. • Ballistic guide, beam splitter, beam bender

High-level waste borosilicate glass: A compendium of corrosion characteristics. Volume 2

International Nuclear Information System (INIS)

Cunnane, J.C.

1994-03-01

The objective of this document is to summarize scientific information pertinent to evaluating the extent to which high-level waste borosilicate glass corrosion and the associated radionuclide release processes are understood for the range of environmental conditions to which waste glass may be exposed in service. Alteration processes occurring within the bulk of the glass (e.g., devitrification and radiation-induced changes) are discussed insofar as they affect glass corrosion.This document is organized into three volumes. Volumes I and II represent a tiered set of information intended for somewhat different audiences. Volume I is intended to provide an overview of waste glass corrosion, and Volume 11 is intended to provide additional experimental details on experimental factors that influence waste glass corrosion. Volume III contains a bibliography of glass corrosion studies, including studies that are not cited in Volumes I and II. Volume I is intended for managers, decision makers, and modelers, the combined set of Volumes I, II, and III is intended for scientists and engineers working in the field of high-level waste

High-level waste borosilicate glass: A compendium of corrosion characteristics. Volume 2

Energy Technology Data Exchange (ETDEWEB)

Cunnane, J.C. [comp.; Bates, J.K.; Bradley, C.R. [Argonne National Lab., IL (United States)] [and others

1994-03-01

The objective of this document is to summarize scientific information pertinent to evaluating the extent to which high-level waste borosilicate glass corrosion and the associated radionuclide release processes are understood for the range of environmental conditions to which waste glass may be exposed in service. Alteration processes occurring within the bulk of the glass (e.g., devitrification and radiation-induced changes) are discussed insofar as they affect glass corrosion.This document is organized into three volumes. Volumes I and II represent a tiered set of information intended for somewhat different audiences. Volume I is intended to provide an overview of waste glass corrosion, and Volume 11 is intended to provide additional experimental details on experimental factors that influence waste glass corrosion. Volume III contains a bibliography of glass corrosion studies, including studies that are not cited in Volumes I and II. Volume I is intended for managers, decision makers, and modelers, the combined set of Volumes I, II, and III is intended for scientists and engineers working in the field of high-level waste.

Effect of CuO addition on structure and electrical properties of low ...

Indian Academy of Sciences (India)

2016-08-26

Aug 26, 2016 ... Home; Journals; Bulletin of Materials Science; Volume 36; Issue 5. Effect of CuO addition on structure and electrical properties of low temperature sintered quaternary piezoelectric ceramics. Jianhua Li ... Keywords. Sintering; microstructure-final; piezoelectric properties; perovskites; Jahn–Teller effect.

Lung volume recruitment in multiple sclerosis.

Directory of Open Access Journals (Sweden)

Nadim Srour

Full Text Available INTRODUCTION: Pulmonary function abnormalities have been described in multiple sclerosis including reductions in forced vital capacity (FVC and cough but the time course of this impairment is unknown. Peak cough flow (PCF is an important parameter for patients with respiratory muscle weakness and a reduced PCF has a direct impact on airway clearance and may therefore increase the risk of respiratory tract infections. Lung volume recruitment is a technique that improves PCF by inflating the lungs to their maximal insufflation capacity. OBJECTIVES: Our goals were to describe the rate of decline of pulmonary function and PCF in patients with multiple sclerosis and describe the use of lung volume recruitment in this population. METHODS: We reviewed all patients with multiple sclerosis referred to a respiratory neuromuscular rehabilitation clinic from February 1999 until December 2010. Lung volume recruitment was attempted in patients with FVC <80% predicted. Regular twice daily lung volume recruitment was prescribed if it resulted in a significant improvement in the laboratory. RESULTS: There were 79 patients included, 35 of whom were seen more than once. A baseline FVC <80% predicted was present in 82% of patients and 80% of patients had a PCF insufficient for airway clearance. There was a significant decline in FVC (122.6 mL/y, 95% CI 54.9-190.3 and PCF (192 mL/s/y, 95% 72-311 over a median follow-up time of 13.4 months. Lung volume recruitment was associated with a slower decline in FVC (p<0.0001 and PCF (p = 0.042. CONCLUSION: Pulmonary function and cough decline significantly over time in selected patients with multiple sclerosis and lung volume recruitment is associated with a slower rate of decline in lung function and peak cough flow. Given design limitations, additional studies are needed to assess the role of lung volume recruitment in patients with multiple sclerosis.

Critical Qualitative Research Reader. Critical Qualitative Research. Volume 2

Science.gov (United States)

Steinberg, Shirley R., Ed.; Cannella, Gaile S., Ed.

2012-01-01

This volume of transformed research utilizes an activist approach to examine the notion that nothing is apolitical. Research projects themselves are critically examined for power orientations, even as they are used to address curricular problems and educational or societal issues. Philosophical perspectives that have facilitated an understanding…

A combined approach of generalized additive model and bootstrap with small sample sets for fault diagnosis in fermentation process of glutamate.

Science.gov (United States)

Liu, Chunbo; Pan, Feng; Li, Yun

2016-07-29

Glutamate is of great importance in food and pharmaceutical industries. There is still lack of effective statistical approaches for fault diagnosis in the fermentation process of glutamate. To date, the statistical approach based on generalized additive model (GAM) and bootstrap has not been used for fault diagnosis in fermentation processes, much less the fermentation process of glutamate with small samples sets. A combined approach of GAM and bootstrap was developed for the online fault diagnosis in the fermentation process of glutamate with small sample sets. GAM was first used to model the relationship between glutamate production and different fermentation parameters using online data from four normal fermentation experiments of glutamate. The fitted GAM with fermentation time, dissolved oxygen, oxygen uptake rate and carbon dioxide evolution rate captured 99.6 % variance of glutamate production during fermentation process. Bootstrap was then used to quantify the uncertainty of the estimated production of glutamate from the fitted GAM using 95 % confidence interval. The proposed approach was then used for the online fault diagnosis in the abnormal fermentation processes of glutamate, and a fault was defined as the estimated production of glutamate fell outside the 95 % confidence interval. The online fault diagnosis based on the proposed approach identified not only the start of the fault in the fermentation process, but also the end of the fault when the fermentation conditions were back to normal. The proposed approach only used a small sample sets from normal fermentations excitements to establish the approach, and then only required online recorded data on fermentation parameters for fault diagnosis in the fermentation process of glutamate. The proposed approach based on GAM and bootstrap provides a new and effective way for the fault diagnosis in the fermentation process of glutamate with small sample sets.

Automated force volume image processing for biological samples.

Directory of Open Access Journals (Sweden)

Pavel Polyakov

2011-04-01

Full Text Available Atomic force microscopy (AFM has now become a powerful technique for investigating on a molecular level, surface forces, nanomechanical properties of deformable particles, biomolecular interactions, kinetics, and dynamic processes. This paper specifically focuses on the analysis of AFM force curves collected on biological systems, in particular, bacteria. The goal is to provide fully automated tools to achieve theoretical interpretation of force curves on the basis of adequate, available physical models. In this respect, we propose two algorithms, one for the processing of approach force curves and another for the quantitative analysis of retraction force curves. In the former, electrostatic interactions prior to contact between AFM probe and bacterium are accounted for and mechanical interactions operating after contact are described in terms of Hertz-Hooke formalism. Retraction force curves are analyzed on the basis of the Freely Jointed Chain model. For both algorithms, the quantitative reconstruction of force curves is based on the robust detection of critical points (jumps, changes of slope or changes of curvature which mark the transitions between the various relevant interactions taking place between the AFM tip and the studied sample during approach and retraction. Once the key regions of separation distance and indentation are detected, the physical parameters describing the relevant interactions operating in these regions are extracted making use of regression procedure for fitting experiments to theory. The flexibility, accuracy and strength of the algorithms are illustrated with the processing of two force-volume images, which collect a large set of approach and retraction curves measured on a single biological surface. For each force-volume image, several maps are generated, representing the spatial distribution of the searched physical parameters as estimated for each pixel of the force-volume image.

Unstructured grids and an element based conservative approach for a black-oil reservoir simulation

Energy Technology Data Exchange (ETDEWEB)

Nogueira, Regis Lopes; Fernandes, Bruno Ramon Batista [Federal University of Ceara, Fortaleza, CE (Brazil). Dept. of Chemical Engineering; Araujo, Andre Luiz de Souza [Federal Institution of Education, Science and Technology of Ceara - IFCE, Fortaleza (Brazil). Industry Department], e-mail: andre@ifce.edu.br; Marcondes, Francisco [Federal University of Ceara, Fortaleza, CE (Brazil). Dept. of Metallurgical Engineering and Material Science], e-mail: marcondes@ufc.br

2010-07-01

Unstructured meshes presented one upgrade in modeling the main important features of the reservoir such as discrete fractures, faults, and irregular boundaries. From several methodologies available, the Element based Finite Volume Method (EbFVM), in conjunction with unstructured meshes, is one methodology that deserves large attention. In this approach, the reservoir, for 2D domains, is discretized using a mixed two-dimensional mesh using quadrilateral and triangle elements. After the initial step of discretization, each element is divided into sub-elements and the mass balance for each component is developed for each sub-element. The equations for each control-volume using a cell vertex construction are formulated through the contribution of different neighboured elements. This paper presents an investigation of an element-based approach using the black-oil model based on pressure and global mass fractions. In this approach, even when all gas phase is dissolved in oil phase the global mass fraction of gas will be different from zero. Therefore, no additional numerical procedure is necessary in order to treat the gas phase appear/disappearance. In this paper the above mentioned approach is applied to multiphase flows involving oil, gas, and water. The mass balance equations in terms of global mass fraction of oil, gas and water are discretized through the EbFVM and linearized by the Newton's method. The results are presented in terms of volumetric rates of oil, gas, and water and phase saturations. (author)

Handbook of the Economics of Education. Volume 3

Science.gov (United States)

Hanushek, Eric A., Ed.; Machin, Stephen J., Ed.; Woessmann, Ludger, Ed.

2011-01-01

How does education affect economic and social outcomes, and how can it inform public policy? Volume 3 of the Handbooks in the Economics of Education uses newly available high quality data from around the world to address these and other core questions. With the help of new methodological approaches, contributors cover econometric methods and…

Grey matter volumes in treatment naïve vs. chronically treated children with attention deficit/hyperactivity disorder: a combined approach.

Science.gov (United States)

Villemonteix, Thomas; De Brito, Stéphane A; Kavec, Martin; Balériaux, Danielle; Metens, Thierry; Slama, Hichem; Baijot, Simon; Mary, Alison; Peigneux, Philippe; Massat, Isabelle

2015-08-01

Psychostimulants are the first-line treatment in attention deficit/hyperactivity disorder (ADHD), but their effects on brain development remain poorly understood. In particular, previous structural magnetic resonance imaging (sMRI) studies only investigated treatment effects on grey matter (GM) volumes in selected regions of interest (ROIs). In this study, voxel-based morphometry (VBM) was used to assess medication-related GM volume differences across the entire brain. Automated tracing measurements of selected ROIs were also obtained. Three groups (77 participants aged 7-to-13 year old) underwent MRI scans and were compared: never-medicated children with ADHD (n=33), medicated (methylphenidate) children with ADHD (n=20) and typically developing children (TD; n=24). Optimised VBM was used to investigate regional GM volumes, controlling for age and gender. Automated tracing procedures were also used to assess the average volume of the caudate nucleus, the amygdala and the nucleus accumbens. When compared to both medicated children with ADHD and TD children, never-medicated children with ADHD exhibited decreased GM volume in the insula and in the middle temporal gyrus. When compared to TD children, medicated children with ADHD had decreased GM volume in the middle frontal gyrus and in the precentral gyrus. Finally, ROI analyses revealed a significant association between duration of treatment and GM volume of the left nucleus accumbens in medicated children with ADHD. In conclusion, this study documents potential methylphenidate-related GM volume normalization and deviation in previously unexplored brain structures, and reports a positive association between treatment history and GM volume in the nucleus accumbens, a key region for reward-processing. Copyright © 2015 Elsevier B.V. and ECNP. All rights reserved.

Review on Electrodynamic Energy Harvesters—A Classification Approach

Directory of Open Access Journals (Sweden)

Roland Lausecker

2013-04-01

Full Text Available Beginning with a short historical sketch, electrodynamic energy harvesters with focus on vibration generators and volumes below 1dm3 are reviewed. The current challenges to generate up to several milliwatts of power from practically relevant flows and vibrations are addressed, and the variety of available solutions is sketched. Sixty-seven different harvester concepts from more than 130 publications are classified with respect to excitation, additional boundary conditions, design and fabrication. A chronological list of the harvester concepts with corresponding references provides an impression about the developments. Besides resonant harvester concepts, the review includes broadband approaches and mechanisms to harvest from flow. Finally, a short overview of harvesters in applications and first market ready concepts is given.

Pulmonary blood volume and transit time in cirrhosis: relation to lung function

DEFF Research Database (Denmark)

Møller, Søren; Burchardt, H; Øgard, CG

2006-01-01

BACKGROUND/AIMS: In cirrhosis a systemic vasodilatation leads to an abnormal distribution of the blood volume with a contracted central blood volume. In addition, the patients have a ventilation/perfusion imbalance with a low diffusing capacity. As the size of the pulmonary blood volume (PBV) has...... not been determined separately we assessed PBV and pulmonary transit time (PTT) in relation to lung function in patients with cirrhosis and in controls. METHODS: Pulmonary and cardiac haemodynamics and transit times were determined by radionuclide techniques in 22 patients with alcoholic cirrhosis......, in the controls, Pvolume...

Comparison of different volume markers in peritoneal dialysis

International Nuclear Information System (INIS)

De Paepe, M.; Belpaire, F.; Schelstraete, K.; Lameire, N.

1988-01-01

Four peritoneal volume markers (carbon 14 -labeled dextran, dextran blue, radioactive albumin, and hemoglobin) were compared. In six rabbits 14 C-dextran was compared with dextran blue during a 4-hour dwell with a 4.25% dextrose solution. The recovery of 14 C-dextran at the end of the dwell was 71% +/- 3% vs. 92% +/- 1% for dextran blue (P less than 0.001). In six other rabbits, radioactive albumin (RISA) was compared with dextran blue. The recovery of RISA was 78% +/- 4%, compared with 85% +/- 2% for dextran blue (P less than 0.05). The calculated peritoneal volumes, uncorrected for disappearance of the markers, were consistently higher than when correction was made. After correction, the calculated end volumes were similar to actually measured end volumes. In six patients with chronic ambulatory peritoneal dialysis, the intraperitoneal volume during a single dwell of 6 hours was estimated in paired observations with lactated Ringer's solution and 1.5% dextrose dialysate, using simultaneously autologous hemoglobin and RISA. In eight additional patients, a single dwell with 4.25% dextrose dialysate was studied. The recoveries of both markers were related to the osmotic strength of the dialysate. Recoveries were 66.7% +/- 2.3% and 69.6% +/- 0.9% in lactated Ringer's solution, and increased to 81% +/- 3% and 82% +/- 2% in 4.25% dextrose for hemoglobin and RISA, respectively. With each dialysate, after correction for disappearance of the marker, no differences in volume profiles or between calculated or measured end volumes could be found with either hemoglobin or RISA

Treatment plan evaluation using dose-volume histogram (DVH) and spatial dose-volume histogram (zDVH)

International Nuclear Information System (INIS)

Cheng, C.-W.; Das, Indra J.

1999-01-01

37% of the bladder wall and 43% of the rectal wall. The zDVHs of the bladder revealed that the hot-spot region was superior to the central axis. The zDVHs of the rectum showed that the high-dose region was an 8-cm segment mostly superior to the central axis. The serial array-like of the rectum warrants a closer attention with regard to the complication probability of the organ. Conclusions: Although DVH provides an averaged dose-volume information, zDVH provides differential dose-volume information with respect to the CT slice position. zDVH is a 2D analog of a 3D DVH and, in some situations, more superior. It provides additional information on plan evaluation that otherwise could not be appreciated. The zDVH may be used along with DVH for plan evaluation and for the correlation of radiation outcome

Efficient estimation of an additive quantile regression model

NARCIS (Netherlands)

Cheng, Y.; de Gooijer, J.G.; Zerom, D.

2011-01-01

In this paper, two non-parametric estimators are proposed for estimating the components of an additive quantile regression model. The first estimator is a computationally convenient approach which can be viewed as a more viable alternative to existing kernel-based approaches. The second estimator

Volume-constrained optimization of magnetorheological and electrorheological valves and dampers

Science.gov (United States)

Rosenfeld, Nicholas C.; Wereley, Norman M.

2004-12-01

This paper presents a case study of magnetorheological (MR) and electrorheological (ER) valve design within a constrained cylindrical volume. The primary purpose of this study is to establish general design guidelines for volume-constrained MR valves. Additionally, this study compares the performance of volume-constrained MR valves against similarly constrained ER valves. Starting from basic design guidelines for an MR valve, a method for constructing candidate volume-constrained valve geometries is presented. A magnetic FEM program is then used to evaluate the magnetic properties of the candidate valves. An optimized MR valve is chosen by evaluating non-dimensional parameters describing the candidate valves' damping performance. A derivation of the non-dimensional damping coefficient for valves with both active and passive volumes is presented to allow comparison of valves with differing proportions of active and passive volumes. The performance of the optimized MR valve is then compared to that of a geometrically similar ER valve using both analytical and numerical techniques. An analytical equation relating the damping performances of geometrically similar MR and ER valves in as a function of fluid yield stresses and relative active fluid volume, and numerical calculations are provided to calculate each valve's damping performance and to validate the analytical calculations.

Porosity of Self-Compacting Concrete (SCC) incorporating high volume fly ash

Science.gov (United States)

Kristiawan, S. A.; Sunarmasto; Murti, G. Y.

2017-02-01

Degradation of concrete could be triggered by the presence of aggressive agents from the environment into the body of concrete. The penetration of these agents is influenced by the pore characteristics of the concrete. Incorporating a pozzolanic material such as fly ash could modify the pore characteristic of the concrete. This research aims to investigate the influence of incorporating fly ash at high volume level on the porosity of Self-Compacting Concrete (SCC). Laboratory investigations were carried out following the ASTM C642 for measuring density and volume of permeable pores (voids) of the SCC with varying fly ash contents (50-70% by weight of total binder). In addition, a measurement of permeable voids by saturation method was carried out to obtain an additional volume of voids that could not be measured by the immersion and boiling method of ASTM C642. The results show that the influence of fly ash content on the porosity appears to be dependent on age of SCC. At age less than 56 d, fly ash tends to cause an increase of voids but at 90 d of age it reduces the pores. The additional pores that can be penetrated by vacuum saturation method counts about 50% of the total voids.

Risk factors influencing the pleural drainage volume after transthoracic oesophagectomy.

Science.gov (United States)

Kosugi, Shin-ichi; Kanda, Tatsuo; Yajima, Kazuhito; Ishikawa, Takashi; Sakamoto, Kaoru

2013-06-01

The objective of this study was to clarify the factors influencing pleural drainage volume after transthoracic oesophagectomy and to determine criteria for the selection of patients who would benefit from the early removal of chest drains. Clinicopathological characteristics of 155 patients who underwent transthoracic oesophagectomy were prospectively collected, and the daily drainage volume of each patient was retrospectively reviewed. Potential risk factors were compared between the high-output group (n = 39) and low-output group (n = 116), which were dichotomized using the 75th percentile of total pleural drainage volume of the total study population. Multivariate logistic regression analyses were used to identify independent risk factors. The median duration of drainage was 10 days, with a median total drainage volume of 2258 ml. Of 27 potential risk factors influencing the drainage volume, creatinine clearance (P = 0.04), operative approach (P = 0.03) and thoracic duct removal (P = 0.01) were significantly associated with the total pleural drainage volume. The removal of the thoracic duct (P = 0.02; odds ratio, 4.02; 95% confidence interval 1.20-13.41) and lower creatinine clearance (P = 0.04; odds ratio, 1.02; 95% confidence interval 1.00-1.04) was independent risk factors for increased pleural drainage volume after transthoracic oesophagectomy. The early removal of chest drains may be possible in patients without these risk factors.

A Tsunami Ball Approach to Storm Surge and Inundation: Application to Hurricane Katrina, 2005

Directory of Open Access Journals (Sweden)

Steven N. Ward

2009-01-01

Full Text Available Most analyses of storm surge and inundation solve equations of continuity and momentum on fixed finite-difference/finite-element meshes. I develop a completely new approach that uses a momentum equation to accelerate bits or balls of water over variable depth topography. The thickness of the water column at any point equals the volume density of balls there. In addition to being more intuitive than traditional methods, the tsunami ball approach has several advantages. (a By tracking water balls of fixed volume, the continuity equation is satisfied automatically and the advection term in the momentum equation becomes unnecessary. (b The procedure is meshless in the finite-difference/finite-element sense. (c Tsunami balls care little if they find themselves in the ocean or inundating land. (d Tsunami ball calculations of storm surge can be done on a laptop computer. I demonstrate and calibrate the method by simulating storm surge and inundation around New Orleans, Louisiana caused by Hurricane Katrina in 2005 and by comparing model predictions with field observations. To illustrate the flexibility of the tsunami ball technique, I run two “What If” hurricane scenarios—Katrina over Savannah, Georgia and Katrina over Cape Cod, Massachusetts.

Influence of metallic additives on manganese ferrites sintering

Science.gov (United States)

Shevelev, S. A.; Luchnikov, P. A.; Yarullina, A. R.

2018-01-01

Influence of cuprum nanopowder additive received by electric explosion on the process of manganese ferrites MgFe2O4 consolidating at thermal sintering was researched by dilatometry method. Cuprum nanopowder at a rate of 5 mass % was added into the original commercial-grade powder of manganese ferrite MgFe2O4. Powder mixture was numerously blended with screening for better blending before pressing. Powder compacts were formed by cold one-axle static pressing. It was proved that introduction of cuprum additive caused shrinkage increase at final heating stage. There was abnormal compact enlarging at sintering in the air at isothermal stage; the specified process was not observed in vacuum. This difference can be explained by changes in conditions of gaseous discharge from volume of pores.

Cognitive neuroscience robotics A synthetic approaches to human understanding

CERN Document Server

Ishiguro, Hiroshi; Asada, Minoru; Osaka, Mariko; Fujikado, Takashi

2016-01-01

Cognitive Neuroscience Robotics is the first introductory book on this new interdisciplinary area. This book consists of two volumes, the first of which, Synthetic Approaches to Human Understanding, advances human understanding from a robotics or engineering point of view. The second, Analytic Approaches to Human Understanding, addresses related subjects in cognitive science and neuroscience. These two volumes are intended to complement each other in order to more comprehensively investigate human cognitive functions, to develop human-friendly information and robot technology (IRT) systems, and to understand what kind of beings we humans are. Volume A describes how human cognitive functions can be replicated in artificial systems such as robots, and investigates how artificial systems could acquire intelligent behaviors through interaction with others and their environment.

Properties of Resistive Hydrogen Sensors as a Function of Additives of 3 D-Metals Introduced in the Volume of Thin Nanocrystalline SnO2 Films

Science.gov (United States)

Sevast'yanov, E. Yu.; Maksimova, N. K.; Potekaev, A. I.; Sergeichenko, N. V.; Chernikov, E. V.; Almaev, A. V.; Kushnarev, B. O.

2017-11-01

Analysis of the results of studying electrical and gas sensitive characteristics of the molecular hydrogen sensors based on thin nanocrystalline SnO2 films coated with dispersed Au layers and containing Au+Ni and Au+Co impurities in the bulk showed that the characteristics of these sensors are more stable under the prolonged exposure to hydrogen in comparison with Au/SnO2:Sb, Au films modified only with gold. It has been found that introduction of the nickel and cobalt additives increases the band bending at the grain boundaries of tin dioxide already in freshly prepared samples, which indicates an increase in the density Ni of the chemisorbed oxygen. It is important that during testing, the band bending eφs at the grain boundaries of tin dioxide additionally slightly increases. It can be assumed that during crystallization of films under thermal annealing, the 3d-metal atoms in the SnO2 volume partially segregate on the surface of microcrystals and form bonds with lattice oxygen, the superstoichiometric tin atoms are formed, and the density Ni increases. If the bonds of oxygen with nickel and cobalt are stronger than those with tin, then, under the prolonged tests, atomic hydrogen will be oxidized not by lattice oxygen, but mainly by the chemisorbed one. In this case, stability of the sensors' characteristics increases.

Bounding approaches to system identification

CERN Document Server

Norton, John; Piet-Lahanier, Hélène; Walter, Éric

1996-01-01

In response to the growing interest in bounding error approaches, the editors of this volume offer the first collection of papers to describe advances in techniques and applications of bounding of the parameters, or state variables, of uncertain dynamical systems. Contributors explore the application of the bounding approach as an alternative to the probabilistic analysis of such systems, relating its importance to robust control-system design.

Using deep learning to segment breast and fibroglandular tissue in MRI volumes.

Science.gov (United States)

Dalmış, Mehmet Ufuk; Litjens, Geert; Holland, Katharina; Setio, Arnaud; Mann, Ritse; Karssemeijer, Nico; Gubern-Mérida, Albert

2017-02-01

Automated segmentation of breast and fibroglandular tissue (FGT) is required for various computer-aided applications of breast MRI. Traditional image analysis and computer vision techniques, such atlas, template matching, or, edge and surface detection, have been applied to solve this task. However, applicability of these methods is usually limited by the characteristics of the images used in the study datasets, while breast MRI varies with respect to the different MRI protocols used, in addition to the variability in breast shapes. All this variability, in addition to various MRI artifacts, makes it a challenging task to develop a robust breast and FGT segmentation method using traditional approaches. Therefore, in this study, we investigated the use of a deep-learning approach known as "U-net." We used a dataset of 66 breast MRI's randomly selected from our scientific archive, which includes five different MRI acquisition protocols and breasts from four breast density categories in a balanced distribution. To prepare reference segmentations, we manually segmented breast and FGT for all images using an in-house developed workstation. We experimented with the application of U-net in two different ways for breast and FGT segmentation. In the first method, following the same pipeline used in traditional approaches, we trained two consecutive (2C) U-nets: first for segmenting the breast in the whole MRI volume and the second for segmenting FGT inside the segmented breast. In the second method, we used a single 3-class (3C) U-net, which performs both tasks simultaneously by segmenting the volume into three regions: nonbreast, fat inside the breast, and FGT inside the breast. For comparison, we applied two existing and published methods to our dataset: an atlas-based method and a sheetness-based method. We used Dice Similarity Coefficient (DSC) to measure the performances of the automated methods, with respect to the manual segmentations. Additionally, we computed

A novel approach for quantitation of glucosylceramide in human dried blood spot using LC-MS/MS.

Science.gov (United States)

Ji, Allena Ji; Wang, Haixing; Ziso-Qejvanaj, Enida; Zheng, Kefei; Chung, Lee Lee; Foley, Timothy; Chuang, Wei-Lien; Richards, Susan; Sung, Crystal

2015-01-01

Glucosylceramide, an efficacy biomarker for Gaucher Type 1 disease, exhibits poor solubility in polar solvents and whole blood which makes it difficult to prepare a homogenous blood standard. We developed a novel method using standard addition approach by spiking a small volume of analyte solution on the surface of prespotted dried blood spot. The whole spots were punched out for subsequent extraction and LC-MS/MS analysis. The assay performance met all validation acceptance criteria. Glucosylceramide concentrations in 50 paired plasma and dry blood spot samples obtained from Gaucher Type 1 patients were tested and the results demonstrated the feasibility of using the DBS method for clinical biomarker monitoring. The new approach greatly improves assay precision and accuracy.

Optimal models of extreme volume-prices are time-dependent

International Nuclear Information System (INIS)

Rocha, Paulo; Boto, João Pedro; Raischel, Frank; Lind, Pedro G

2015-01-01

We present evidence that the best model for empirical volume-price distributions is not always the same and it strongly depends in (i) the region of the volume-price spectrum that one wants to model and (ii) the period in time that is being modelled. To show these two features we analyze stocks of the New York stock market with four different models: Γ, Γ-inverse, log-normal, and Weibull distributions. To evaluate the accuracy of each model we use standard relative deviations as well as the Kullback-Leibler distance and introduce an additional distance particularly suited to evaluate how accurate are the models for the distribution tails (large volume-price). Finally we put our findings in perspective and discuss how they can be extended to other situations in finance engineering

The Voronoi volume and molecular representation of molar volume: equilibrium simple fluids.

Science.gov (United States)

Hunjan, Jagtar Singh; Eu, Byung Chan

2010-04-07

The Voronoi volume of simple fluids was previously made use of in connection with volume transport phenomena in nonequilibrium simple fluids. To investigate volume transport phenomena, it is important to develop a method to compute the Voronoi volume of fluids in nonequilibrium. In this work, as a first step to this goal, we investigate the equilibrium limit of the nonequilibrium Voronoi volume together with its attendant related molar (molal) and specific volumes. It is proved that the equilibrium Voronoi volume is equivalent to the molar (molal) volume. The latter, in turn, is proved equivalent to the specific volume. This chain of equivalences provides an alternative procedure of computing the equilibrium Voronoi volume from the molar volume/specific volume. We also show approximate methods of computing the Voronoi and molar volumes from the information on the pair correlation function. These methods may be employed for their quick estimation, but also provide some aspects of the fluid structure and its relation to the Voronoi volume. The Voronoi volume obtained from computer simulations is fitted to a function of temperature and pressure in the region above the triple point but below the critical point. Since the fitting function is given in terms of reduced variables for the Lennard-Jones (LJ) model and the kindred volumes (i.e., specific and molar volumes) are in essence equivalent to the equation of state, the formula obtained is a reduced equation state for simple fluids obeying the LJ model potential in the range of temperature and pressure examined and hence can be used for other simple fluids.

Thalamic Volume Is Reduced in Cervical and Laryngeal Dystonias.

Science.gov (United States)

Waugh, Jeff L; Kuster, John K; Levenstein, Jacob M; Makris, Nikos; Multhaupt-Buell, Trisha J; Sudarsky, Lewis R; Breiter, Hans C; Sharma, Nutan; Blood, Anne J

2016-01-01

Dystonia, a debilitating movement disorder characterized by abnormal fixed positions and/or twisting postures, is associated with dysfunction of motor control networks. While gross brain lesions can produce secondary dystonias, advanced neuroimaging techniques have been required to identify network abnormalities in primary dystonias. Prior neuroimaging studies have provided valuable insights into the pathophysiology of dystonia, but few directly assessed the gross volume of motor control regions, and to our knowledge, none identified abnormalities common to multiple types of idiopathic focal dystonia. We used two gross volumetric segmentation techniques and one voxelwise volumetric technique (voxel based morphometry, VBM) to compare regional volume between matched healthy controls and patients with idiopathic primary focal dystonia (cervical, n = 17, laryngeal, n = 7). We used (1) automated gross volume measures of eight motor control regions using the FreeSurfer analysis package; (2) blinded, anatomist-supervised manual segmentation of the whole thalamus (also gross volume); and (3) voxel based morphometry, which measures local T1-weighted signal intensity and estimates gray matter density or volume at the level of single voxels, for both whole-brain and thalamus. Using both automated and manual gross volumetry, we found a significant volume decrease only in the thalamus in two focal dystonias. Decreases in whole-thalamic volume were independent of head and brain size, laterality of symptoms, and duration. VBM measures did not differ between dystonia and control groups in any motor control region. Reduced thalamic gross volume, detected in two independent analyses, suggests a common anatomical abnormality in cervical dystonia and spasmodic dysphonia. Defining the structural underpinnings of dystonia may require such complementary approaches.

Thalamic Volume Is Reduced in Cervical and Laryngeal Dystonias.

Directory of Open Access Journals (Sweden)

Jeff L Waugh

Full Text Available Dystonia, a debilitating movement disorder characterized by abnormal fixed positions and/or twisting postures, is associated with dysfunction of motor control networks. While gross brain lesions can produce secondary dystonias, advanced neuroimaging techniques have been required to identify network abnormalities in primary dystonias. Prior neuroimaging studies have provided valuable insights into the pathophysiology of dystonia, but few directly assessed the gross volume of motor control regions, and to our knowledge, none identified abnormalities common to multiple types of idiopathic focal dystonia.We used two gross volumetric segmentation techniques and one voxelwise volumetric technique (voxel based morphometry, VBM to compare regional volume between matched healthy controls and patients with idiopathic primary focal dystonia (cervical, n = 17, laryngeal, n = 7. We used (1 automated gross volume measures of eight motor control regions using the FreeSurfer analysis package; (2 blinded, anatomist-supervised manual segmentation of the whole thalamus (also gross volume; and (3 voxel based morphometry, which measures local T1-weighted signal intensity and estimates gray matter density or volume at the level of single voxels, for both whole-brain and thalamus.Using both automated and manual gross volumetry, we found a significant volume decrease only in the thalamus in two focal dystonias. Decreases in whole-thalamic volume were independent of head and brain size, laterality of symptoms, and duration. VBM measures did not differ between dystonia and control groups in any motor control region.Reduced thalamic gross volume, detected in two independent analyses, suggests a common anatomical abnormality in cervical dystonia and spasmodic dysphonia. Defining the structural underpinnings of dystonia may require such complementary approaches.

Thalamic Volume Is Reduced in Cervical and Laryngeal Dystonias

Science.gov (United States)

Waugh, Jeff L.; Kuster, John K.; Levenstein, Jacob M.; Makris, Nikos; Multhaupt-Buell, Trisha J.; Sudarsky, Lewis R.; Breiter, Hans C.; Sharma, Nutan; Blood, Anne J.

2016-01-01

Background Dystonia, a debilitating movement disorder characterized by abnormal fixed positions and/or twisting postures, is associated with dysfunction of motor control networks. While gross brain lesions can produce secondary dystonias, advanced neuroimaging techniques have been required to identify network abnormalities in primary dystonias. Prior neuroimaging studies have provided valuable insights into the pathophysiology of dystonia, but few directly assessed the gross volume of motor control regions, and to our knowledge, none identified abnormalities common to multiple types of idiopathic focal dystonia. Methods We used two gross volumetric segmentation techniques and one voxelwise volumetric technique (voxel based morphometry, VBM) to compare regional volume between matched healthy controls and patients with idiopathic primary focal dystonia (cervical, n = 17, laryngeal, n = 7). We used (1) automated gross volume measures of eight motor control regions using the FreeSurfer analysis package; (2) blinded, anatomist-supervised manual segmentation of the whole thalamus (also gross volume); and (3) voxel based morphometry, which measures local T1-weighted signal intensity and estimates gray matter density or volume at the level of single voxels, for both whole-brain and thalamus. Results Using both automated and manual gross volumetry, we found a significant volume decrease only in the thalamus in two focal dystonias. Decreases in whole-thalamic volume were independent of head and brain size, laterality of symptoms, and duration. VBM measures did not differ between dystonia and control groups in any motor control region. Conclusions Reduced thalamic gross volume, detected in two independent analyses, suggests a common anatomical abnormality in cervical dystonia and spasmodic dysphonia. Defining the structural underpinnings of dystonia may require such complementary approaches. PMID:27171035

ESTIMATING WOOD VOLUME FOR PINUS BRUTIA TREES IN FOREST STANDS FROM QUICKBIRD-2 IMAGERY

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P. Patias

2016-06-01

Full Text Available Knowledge of forest parameters, such as wood volume, is required for a sustainable forest management. Collecting such information in the field is laborious and even not feasible in inaccessible areas. In this study, tree wood volume is estimated utilizing remote sensing techniques, which can facilitate the extraction of relevant information. The study area is the University Forest of Taxiarchis, which is located in central Chalkidiki, Northern Greece and covers an area of 58km2. The tree species under study is the conifer evergreen species P. brutia (Calabrian pine. Three plot surfaces of 10m radius were used. VHR Quickbird-2 images are used in combination with an allometric relationship connecting the Tree Crown with the Diameter at breast height (Dbh, and a volume table developed for Greece. The overall methodology is based on individual tree crown delineation, based on (a the marker-controlled watershed segmentation approach and (b the GEographic Object-Based Image Analysis approach. The aim of the first approach is to extract separate segments each of them including a single tree and eventual lower vegetation, shadows, etc. The aim of the second approach is to detect and remove the “noisy” background. In the application of the first approach, the Blue, Green, Red, Infrared and PCA-1 bands are tested separately. In the application of the second approach, NDVI and image brightness thresholds are utilized. The achieved results are evaluated against field plot data. Their observed difference are between -5% to +10%.

The spill prevention, control, and countermeasures (SPCC) plan for the Y-12 Plant. Volume 1

Energy Technology Data Exchange (ETDEWEB)

1992-08-01

This spill prevention, control and countermeasures (SPCC) Plan is divided into two volumes. Volume I addresses Y-12`s compliance with regulations pertinent to the content of SPCC Plans. Volume II is the SPCC Hazardous Material Storage Data Base, a detailed tabulation of facility-specific information and data on potential spill sources at the Y-12 Plant. Volume I follows the basic format and subject sequence specified in 40 CFR 112.7. This sequence is prefaced by three additional chapters, including this introduction and brief discussions of the Y-12 Plant`s background/environmental setting and potential spill source categories. Two additional chapters on containers and container storage areas and PCB and PCB storage for disposal facilities are inserted into the required sequence. The following required subjects are covered in this volume: Spill history, site drainage; secondary containment/diversion structures and equipment; contingency plans; notification and spill response procedures; facility drainage; bulk storage tanks; facility transfer operations, pumping, and in-plant processes; transfer stations (facility tank cars/tank tracks); inspections and records; security, and personnel, training, and spill prevention procedures.

Quantitative study on lung volume and lung perfusion using SPECT and CT in thoracal tumors

International Nuclear Information System (INIS)

Beyer-Enke, S.A.; Goerich, J.; Strauss, L.G.

1988-01-01

22 patients with space occupying lesions in the thoracal region were investigated by computer tomography and by perfusion scintigraphy using SPECT. In order to evaluate the CT images quantitatively, the lung volume was determined using approximation method and compared with the perfusion in the SPECT study. For this, anatomically equivalent transaxial SPECT slices had been coordinated to the CT slices. Between the determined lung volumes and the activity in the ocrresponding layers, a statistically significant correlation was found. It could be shown that the stronger perfusion, frequently observed at the right side of the healthy lung, may be explained by an higher volume of the right pulmonary lobe. Whereas in benign displacing processes the relation activity to volume was similar to the one of the healthy lung, a strongly reduced perfusion together with inconspicuous lung volumes became apparent with malignant tumors. In addition to the great morphological evidence of CT and SPECT studies, additional informations regarding the dignity of displacing processes may be derived from the quantitative evaluation of both methods. (orig.) [de

Eddy damping effect of additional conductors in superconducting levitation systems

Energy Technology Data Exchange (ETDEWEB)

Jiang, Zhao-Fei; Gou, Xiao-Fan, E-mail: xfgou@hhu.edu.cn

2015-12-15

Highlights: • In this article, for the eddy current damper attached to the HTSC, we • quantitatively investigated the damping coefficient c, damping ratio, Joule heating of the copper damper, and the vibration frequency of the PM as well. • presented four different arrangements of the copper damper, and comparatively studied their damping effects and Joule heating, and finally proposed the most advisable arrangement. - Abstract: Passive superconducting levitation systems consisting of a high temperature superconductor (HTSC) and a permanent magnet (PM) have demonstrated several fascinating applications such as the maglev system, flywheel energy storage. Generally, for the HTSC–PM levitation system, the HTSC with higher critical current density J{sub c} can obtain larger magnetic force to make the PM levitate over the HTSC (or suspended below the HTSC), however, the process of the vibration of the levitated PM, provides very limited inherent damping (essentially hysteresis). To improve the dynamic stability of the levitated PM, eddy damping of additional conductors can be considered as the most simple and effective approach. In this article, for the HTSC–PM levitation system with an additional copper damper attached to the HTSC, we numerically and comprehensively investigated the damping coefficient c, damping ratio, Joule heating of the copper damper, and the vibration frequency of the PM as well. Furthermore, we comparatively studied four different arrangements of the copper damper, on the comprehensive analyzed the damping effect, efficiency (defined by c/V{sub Cu}, in which V{sub Cu} is the volume of the damper) and Joule heating, and finally presented the most advisable arrangement.

Prehospital tidal volume influences hospital tidal volume: A cohort study.

Science.gov (United States)

Stoltze, Andrew J; Wong, Terrence S; Harland, Karisa K; Ahmed, Azeemuddin; Fuller, Brian M; Mohr, Nicholas M

2015-06-01

The purposes of the study are to describe current practice of ventilation in a modern air medical system and to measure the association of ventilation strategy with subsequent ventilator care and acute respiratory distress syndrome (ARDS). Retrospective observational cohort study of intubated adult patients (n = 235) transported by a university-affiliated air medical transport service to a 711-bed tertiary academic center between July 2011 and May 2013. Low tidal volume ventilation was defined as tidal volumes less than or equal to 8 mL/kg predicted body weight. Multivariable regression was used to measure the association between prehospital tidal volume, hospital ventilation strategy, and ARDS. Most patients (57%) were ventilated solely with bag valve ventilation during transport. Mean tidal volume of mechanically ventilated patients was 8.6 mL/kg predicted body weight (SD, 0.2 mL/kg). Low tidal volume ventilation was used in 13% of patients. Patients receiving low tidal volume ventilation during air medical transport were more likely to receive low tidal volume ventilation in the emergency department (P tidal volume (P = .840). Low tidal volume ventilation was rare during air medical transport. Air transport ventilation strategy influenced subsequent ventilation but was not associated with ARDS. Copyright © 2015 Elsevier Inc. All rights reserved.

Teaching Thermal Hydraulics & Numerical Methods: An Introductory Control Volume Primer

Energy Technology Data Exchange (ETDEWEB)

D. S. Lucas

2004-10-01

A graduate level course for Thermal Hydraulics (T/H) was taught through Idaho State University in the spring of 2004. A numerical approach was taken for the content of this course since the students were employed at the Idaho National Laboratory and had been users of T/H codes. The majority of the students had expressed an interest in learning about the Courant Limit, mass error, semi-implicit and implicit numerical integration schemes in the context of a computer code. Since no introductory text was found the author developed notes taught from his own research and courses taught for Westinghouse on the subject. The course started with a primer on control volume methods and the construction of a Homogeneous Equilibrium Model (HEM) (T/H) code. The primer was valuable for giving the students the basics behind such codes and their evolution to more complex codes for Thermal Hydraulics and Computational Fluid Dynamics (CFD). The course covered additional material including the Finite Element Method and non-equilibrium (T/H). The control volume primer and the construction of a three-equation (mass, momentum and energy) HEM code are the subject of this paper . The Fortran version of the code covered in this paper is elementary compared to its descendants. The steam tables used are less accurate than the available commercial version written in C Coupled to a Graphical User Interface (GUI). The Fortran version and input files can be downloaded at www.microfusionlab.com.

[Evaluation of tidal volume delivered by ventilators during volume-controlled ventilation].

Science.gov (United States)

Zhou, Juan; Yan, Yong; Cao, Desen

2014-12-01

To study the ways which ensure the delivery of enough tidal volume to patients under various conditions close to the demand of the physician. The volume control ventilation model was chosen, and the simulation lung type was active servo lung ASL 5000 or Michigan lung 1601. The air resistance, air compliance and lung type in simulation lungs were set. The tidal volume was obtained from flow analyzer PF 300. At the same tidal volume, the displaying values of tidal volume of E5, Servo i, Evital 4, and Evital XL ventilators with different lung types of patient, compliance of gas piping, leakage, gas types, etc. were evaluated. With the same setting tidal volume of a same ventilator, the tidal volume delivered to patients was different with different lung types of patient, compliance of gas piping, leakage, gas types, etc. Reducing compliance and increasing resistance of the patient lungs caused high peak airway pressure, the tidal volume was lost in gas piping, and the tidal volume be delivered to the patient lungs was decreased. If the ventilator did not compensate to leakage, the tidal volume delivered to the patient lungs was decreased. When the setting gas type of ventilator did not coincide with that applying to the patient, the tidal volume be delivered to the patient lungs might be different with the setting tidal volume of ventilator. To ensure the delivery of enough tidal volume to patients close to the demand of the physician, containable factors such as the compliance of gas piping, leakage, and gas types should be controlled.

The effect of a period of intense exercise on the marker approach to detect growth hormone doping in sports.

Science.gov (United States)

Voss, Sven Christian; Robinson, Neil; Alsayrafi, Mohammed; Bourdon, Pitre C; Schumacher, Yorck Olaf; Saugy, Martial; Giraud, Sylvain

2014-06-01

The major objective of this study was to investigate the effects of several days of intense exercise on the growth hormone marker approach to detect doping with human growth hormone (hGH). In addition we investigated the effect of changes in plasma volume on the test. Fifteen male athletes performed a simulated nine-day cycling stage race. Blood samples were collected twice daily over a period of 15 days (stage race + three days before and after). Plasma volumes were estimated by the optimized CO Rebreathing method. IGF-1 and P-III-NP were analyzed by Siemens Immulite and Cisbio Assays, respectively. All measured GH 2000 scores were far below the published decision limits for an adverse analytical finding. The period of exercise did not increase the GH-scores; however the accompanying effect of the increase in Plasma Volume yielded in essentially lower GH-scores. We could demonstrate that a period of heavy, long-term exercise with changes in plasma volume does not interfere with the decision limits for an adverse analytical finding. Copyright © 2014 John Wiley & Sons, Ltd.

Hanford spent nuclear fuel project recommended path forward, volume III: Alternatives and path forward evaluation supporting documentation

International Nuclear Information System (INIS)

Fulton, J.C.

1994-10-01

Volume I of the Hanford Spent Nuclear Fuel Project - Recommended Path Forward constitutes an aggressive series of projects to construct and operate systems and facilities to safely retrieve, package, transport, process, and store K Basins fuel and sludge. Volume II provided a comparative evaluation of four Alternatives for the Path Forward and an evaluation for the Recommended Path Forward. Although Volume II contained extensive appendices, six supporting documents have been compiled in Volume III to provide additional background for Volume II

Volume-weighted particle-tracking method for solute-transport modeling; Implementation in MODFLOW–GWT

Science.gov (United States)

Winston, Richard B.; Konikow, Leonard F.; Hornberger, George Z.

2018-02-16

In the traditional method of characteristics for groundwater solute-transport models, advective transport is represented by moving particles that track concentration. This approach can lead to global mass-balance problems because in models of aquifers having complex boundary conditions and heterogeneous properties, particles can originate in cells having different pore volumes and (or) be introduced (or removed) at cells representing fluid sources (or sinks) of varying strengths. Use of volume-weighted particles means that each particle tracks solute mass. In source or sink cells, the changes in particle weights will match the volume of water added or removed through external fluxes. This enables the new method to conserve mass in source or sink cells as well as globally. This approach also leads to potential efficiencies by allowing the number of particles per cell to vary spatially—using more particles where concentration gradients are high and fewer where gradients are low. The approach also eliminates the need for the model user to have to distinguish between “weak” and “strong” fluid source (or sink) cells. The new model determines whether solute mass added by fluid sources in a cell should be represented by (1) new particles having weights representing appropriate fractions of the volume of water added by the source, or (2) distributing the solute mass added over all particles already in the source cell. The first option is more appropriate for the condition of a strong source; the latter option is more appropriate for a weak source. At sinks, decisions whether or not to remove a particle are replaced by a reduction in particle weight in proportion to the volume of water removed. A number of test cases demonstrate that the new method works well and conserves mass. The method is incorporated into a new version of the U.S. Geological Survey’s MODFLOW–GWT solute-transport model.

Maintenance Approaches for Different Production Methods

Directory of Open Access Journals (Sweden)

Mungani, Dzivhuluwani Simon

2013-11-01

Full Text Available Various production methods are used in industry to manufacture or produce a variety of products needed by industry and consumers. The nature of a product determines which production method is most suitable or cost-effective. A continuous process is typically used to produce large volumes of liquids or gases. Batch processing is often used for small volumes, such as pharmaceutical products. This paper discusses a research project to determine the relationship between maintenance approaches and production methods. A survey was done to determine to what extent three maintenance approaches reliability-centred maintenance (RCM, total productive maintenance (TPM, and business-centred maintenance (BCM are used for three different processing methods (continuous process, batch process, and a production line method.

Thermodynamic study of (heptane + amine) mixtures. III: Excess and partial molar volumes in mixtures with secondary, tertiary, and cyclic amines at 298.15 K

International Nuclear Information System (INIS)

Lepori, Luciano; Gianni, Paolo; Spanedda, Andrea; Matteoli, Enrico

2011-01-01

Graphical abstract: Highlights: → Excess volumes of (sec., tert., or cyclic amines + heptane) mixtures. → Excess volumes are positive for small size amines and decrease as the size increases. → Group contributions to predict the partial molar volumes of amines in heptane. → The void volume is larger for sec. and tert. than for linear amines in heptane. → The void volume is much smaller for cyclic than for linear amines in heptane. - Abstract: Excess molar volumes V E at 298.15 K were determined by means of a vibrating tube densimeter for binary mixtures of {heptane + open chain secondary (diethyl to dibutyl) and tertiary (triethyl to tripentyl) amines} as well as for cyclic imines (C 2 , C 3 , C 4 , C 6 , and C 7 ) and primary cycloalkylamines (C 5 , C 6 , C 7 , and C 12 ). The V E values were found positive for mixtures involving small size amines, with V E decreasing as the size increases. Negative V E 's were found for tributyl- and tripentylamine, heptamethylenimine, and cyclododecylamine. Mixtures of heptane with cycloheptylamine showed an s-shaped curve. Partial molar volumes V 0 of amines at infinite dilution in heptane were obtained from V E and compared with V 0 of hydrocarbons and other classes of organic compounds taken from literature. An additivity scheme, based on the intrinsic volume approach, was applied to estimate group (CH 3 , CH 2 , CH, C, NH 2 , NH, N, OH, O, CO, and COO) contributions to V 0 . These contributions, the effect of cyclization on V 0 , and the limiting slope of the apparent excess molar volumes were discussed in terms of solute-solvent and solute-solute interactions.

A Computable Plug-In Estimator of Minimum Volume Sets for Novelty Detection

KAUST Repository

Park, Chiwoo; Huang, Jianhua Z.; Ding, Yu

2010-01-01

A minimum volume set of a probability density is a region of minimum size among the regions covering a given probability mass of the density. Effective methods for finding the minimum volume sets are very useful for detecting failures or anomalies in commercial and security applications-a problem known as novelty detection. One theoretical approach of estimating the minimum volume set is to use a density level set where a kernel density estimator is plugged into the optimization problem that yields the appropriate level. Such a plug-in estimator is not of practical use because solving the corresponding minimization problem is usually intractable. A modified plug-in estimator was proposed by Hyndman in 1996 to overcome the computation difficulty of the theoretical approach but is not well studied in the literature. In this paper, we provide theoretical support to this estimator by showing its asymptotic consistency. We also show that this estimator is very competitive to other existing novelty detection methods through an extensive empirical study. ©2010 INFORMS.

A Computable Plug-In Estimator of Minimum Volume Sets for Novelty Detection

KAUST Repository

Park, Chiwoo

2010-10-01

A minimum volume set of a probability density is a region of minimum size among the regions covering a given probability mass of the density. Effective methods for finding the minimum volume sets are very useful for detecting failures or anomalies in commercial and security applications-a problem known as novelty detection. One theoretical approach of estimating the minimum volume set is to use a density level set where a kernel density estimator is plugged into the optimization problem that yields the appropriate level. Such a plug-in estimator is not of practical use because solving the corresponding minimization problem is usually intractable. A modified plug-in estimator was proposed by Hyndman in 1996 to overcome the computation difficulty of the theoretical approach but is not well studied in the literature. In this paper, we provide theoretical support to this estimator by showing its asymptotic consistency. We also show that this estimator is very competitive to other existing novelty detection methods through an extensive empirical study. ©2010 INFORMS.

Large Volume, Behaviorally-relevant Illumination for Optogenetics in Non-human Primates.

Science.gov (United States)

Acker, Leah C; Pino, Erica N; Boyden, Edward S; Desimone, Robert

2017-10-03

This protocol describes a large-volume illuminator, which was developed for optogenetic manipulations in the non-human primate brain. The illuminator is a modified plastic optical fiber with etched tip, such that the light emitting surface area is > 100x that of a conventional fiber. In addition to describing the construction of the large-volume illuminator, this protocol details the quality-control calibration used to ensure even light distribution. Further, this protocol describes techniques for inserting and removing the large volume illuminator. Both superficial and deep structures may be illuminated. This large volume illuminator does not need to be physically coupled to an electrode, and because the illuminator is made of plastic, not glass, it will simply bend in circumstances when traditional optical fibers would shatter. Because this illuminator delivers light over behaviorally-relevant tissue volumes (≈ 10 mm 3 ) with no greater penetration damage than a conventional optical fiber, it facilitates behavioral studies using optogenetics in non-human primates.

Forecasting daily patient volumes in the emergency department.

Science.gov (United States)

Jones, Spencer S; Thomas, Alun; Evans, R Scott; Welch, Shari J; Haug, Peter J; Snow, Gregory L

2008-02-01

seasonal and weekly patterns. The authors compared several time series forecasting methods to a benchmark multiple linear regression model. The results suggest that the existing methodology proposed in the literature, multiple linear regression based on calendar variables, is a reasonable approach to forecasting daily patient volumes in the ED. However, the authors conclude that regression-based models that incorporate calendar variables, account for site-specific special-day effects, and allow for residual autocorrelation provide a more appropriate, informative, and consistently accurate approach to forecasting daily ED patient volumes.

Volume and Surface-Enhanced Volume Negative Ion Sources

International Nuclear Information System (INIS)

Stockli, M P

2013-01-01

H - volume sources and, especially, caesiated H - volume sources are important ion sources for generating high-intensity proton beams, which then in turn generate large quantities of other particles. This chapter discusses the physics and technology of the volume production and the caesium-enhanced (surface) production of H - ions. Starting with Bacal's discovery of the H - volume production, the chapter briefly recounts the development of some H - sources, which capitalized on this process to significantly increase the production of H - beams. Another significant increase was achieved in the 1990s by adding caesiated surfaces to supplement the volume-produced ions with surface-produced ions, as illustrated with other H - sources. Finally, the focus turns to some of the experience gained when such a source was successfully ramped up in H - output and in duty factor to support the generation of 1 MW proton beams for the Spallation Neutron Source. (author)

Simulation-based partial volume correction for dopaminergic PET imaging. Impact of segmentation accuracy

Energy Technology Data Exchange (ETDEWEB)

Rong, Ye; Winz, Oliver H. [University Hospital Aachen (Germany). Dept. of Nuclear Medicine; Vernaleken, Ingo [University Hospital Aachen (Germany). Dept. of Psychiatry, Psychotherapy and Psychosomatics; Goedicke, Andreas [University Hospital Aachen (Germany). Dept. of Nuclear Medicine; High Tech Campus, Philips Research Lab., Eindhoven (Netherlands); Mottaghy, Felix M. [University Hospital Aachen (Germany). Dept. of Nuclear Medicine; Maastricht University Medical Center (Netherlands). Dept. of Nuclear Medicine; Rota Kops, Elena [Forschungszentrum Juelich (Germany). Inst. of Neuroscience and Medicine-4

2015-07-01

Partial volume correction (PVC) is an essential step for quantitative positron emission tomography (PET). In the present study, PVELab, a freely available software, is evaluated for PVC in {sup 18}F-FDOPA brain-PET, with a special focus on the accuracy degradation introduced by various MR-based segmentation approaches. Methods Four PVC algorithms (M-PVC; MG-PVC; mMG-PVC; and R-PVC) were analyzed on simulated {sup 18}F-FDOPA brain-PET images. MR image segmentation was carried out using FSL (FMRIB Software Library) and SPM (Statistical Parametric Mapping) packages, including additional adaptation for subcortical regions (SPM{sub L}). Different PVC and segmentation combinations were compared with respect to deviations in regional activity values and time-activity curves (TACs) of the occipital cortex (OCC), caudate nucleus (CN), and putamen (PUT). Additionally, the PVC impact on the determination of the influx constant (K{sub i}) was assessed. Results Main differences between tissue-maps returned by three segmentation algorithms were found in the subcortical region, especially at PUT. Average misclassification errors in combination with volume reduction was found to be lowest for SPM{sub L} (PUT < 30%) and highest for FSL (PUT > 70%). Accurate recovery of activity data at OCC is achieved by M-PVC (apparent recovery coefficient varies between 0.99 and 1.10). The other three evaluated PVC algorithms have demonstrated to be more suitable for subcortical regions with MG-PVC and mMG-PVC being less prone to the largest tissue misclassification error simulated in this study. Except for M-PVC, quantification accuracy of K{sub i} for CN and PUT was clearly improved by PVC. Conclusions The regional activity value of PUT was appreciably overcorrected by most of the PVC approaches employing FSL or SPM segmentation, revealing the importance of accurate MR image segmentation for the presented PVC framework. The selection of a PVC approach should be adapted to the anatomical

Effect of ethanol/water blends addition on diesel fuel combustion in RCM and DI diesel engine

International Nuclear Information System (INIS)

Nour, Mohamed; Kosaka, Hidenori; Sato, Susumu; Bady, Mahmoud; Abdel-Rahman, Ali K.; Uchida, Kenta

2017-01-01

Highlights: • Effect of ethanol/water addition on diesel combustion studied using optical diagnostics. • The addition of water to ethanol improves engine combustion and soot oxidation. • Ethanol/water injection into exhaust manifold eliminates their endothermic effect. • Ethanol with high water content is recommended for better engine combustion. • Soot concentration reduced by 50% and NO x emissions reduced by 88%. - Abstract: The effect of ethanol/water blends addition on diesel fuel combustion and emissions is investigated experimentally in this study using optical diagnostics. Basic study is performed using rapid compression machine (RCM) under CI conditions. The tested ethanol energy fractions varied in the range of 10–40% of the total added fuel energy, while water volume ratios varied in the range of 10–40% of the injected ethanol. Ethanol and water were evaporated before entering the combustion chamber to eliminate their endothermic effect. Results reveal that addition of ethanol/water blends to diesel fuel results in longer ignition delay and promote the apparent heat release rate (AHRR) at the premixed combustion phase compared to absolute ethanol addition. Additionally, soot and NO x emissions are reduced with ethanol/water addition compared to absolute ethanol addition and neat diesel combustion. The basic study is then extended to investigate the effect ethanol/water blends addition on diesel fuel combustion using single cylinder diesel engine. Waste heat in exhaust manifold is utilized to vaporize ethanol/water blends before combustion. Results reveal that ethanol/water blends injection leads to increase in peak cylinder pressure, indicated mean effective pressure (IMEP), and AHRR at premixed combustion phase. Additionally, the ignition delay increased with ethanol/water addition. NO x emission is decreased up to 88% along with a reduction in soot by 50%. The lower ethanol to water volume ratios show better combustion efficiency, IMEP

Development of Automatic Visceral Fat Volume Calculation Software for CT Volume Data

Directory of Open Access Journals (Sweden)

Mitsutaka Nemoto

2014-01-01

Full Text Available Objective. To develop automatic visceral fat volume calculation software for computed tomography (CT volume data and to evaluate its feasibility. Methods. A total of 24 sets of whole-body CT volume data and anthropometric measurements were obtained, with three sets for each of four BMI categories (under 20, 20 to 25, 25 to 30, and over 30 in both sexes. True visceral fat volumes were defined on the basis of manual segmentation of the whole-body CT volume data by an experienced radiologist. Software to automatically calculate visceral fat volumes was developed using a region segmentation technique based on morphological analysis with CT value threshold. Automatically calculated visceral fat volumes were evaluated in terms of the correlation coefficient with the true volumes and the error relative to the true volume. Results. Automatic visceral fat volume calculation results of all 24 data sets were obtained successfully and the average calculation time was 252.7 seconds/case. The correlation coefficients between the true visceral fat volume and the automatically calculated visceral fat volume were over 0.999. Conclusions. The newly developed software is feasible for calculating visceral fat volumes in a reasonable time and was proved to have high accuracy.

Utility of Quantitative Tc-MAA SPECT/CT for yttrium-Labelled Microsphere Treatment Planning: Calculating Vascularized Hepatic Volume and Dosimetric Approach.

Science.gov (United States)

Garin, Etienne; Rolland, Yan; Lenoir, Laurence; Pracht, Marc; Mesbah, Habiba; Porée, Philippe; Laffont, Sophie; Clement, Bruno; Raoul, Jean-Luc; Boucher, Eveline

2011-01-01

Objectives. The aim of this study was to assess the effectiveness of SPECT/CT for volume measurements and to report a case illustrating the major impact of SPECT/CT in calculating the vascularized liver volume and dosimetry prior to injecting radiolabelled yttrium-90 microspheres (Therasphere). Materials and Methods. This was a phantom study, involving volume measurements carried out by two operators using SPECT and SPECT/CT images. The percentage of error for each method was calculated, and interobserver reproducibility was evaluated. A treatment using Therasphere was planned in a patient with three hepatic arteries, and the quantitative analysis of SPECT/CT for this patient is provided. Results. SPECT/CT volume measurements proved to be accurate (mean error Therasphere used. Conclusions. MAA SPECT/CT is accurate for vascularized liver volume measurements, providing a valuable contribution to the therapeutic planning of patients with complex hepatic vascularization.

The preparation of highly active antimicrobial silver nanoparticles by an organometallic approach

International Nuclear Information System (INIS)

Fernandez, Eduardo J; Garcia-Barrasa, Jorge; Lopez-de-Luzuriaga, Jose M; Monge, Miguel; Laguna, Antonio; Torres, Carmen

2008-01-01

Silver nanoparticles of small size with a high surface to volume ratio have been prepared using an organometallic approach. For this, the complex NBu 4 [Ag(C 6 F 5 ) 2 ] has been treated with AgClO 4 in a 1:1 molar ratio, giving rise to the nanoparticle precursor [Ag(C 6 F 5 )] in solution. Addition of one equivalent of hexadecylamine (HDA) and 5 h of reflux in toluene leads to a deep yellow solution containing monodisperse silver nanoparticles (Ag NPs) of ca. 10 nm. This approach leads to nanoparticles with almost uncontaminated surfaces which make them very reactive. Antimicrobial studies show that these nanoparticles are very active as antimicrobial agents. Very low concentrations between 12 and 25 μg ml -1 of Ag NPs are enough to produce bacteriostatic and bactericidal effectiveness

Exact finite volume expectation values of local operators in excited states

Energy Technology Data Exchange (ETDEWEB)

Pozsgay, B. [MTA-BME “Momentum” Statistical Field Theory Research Group,Budafoki út 8, 1111 Budapest (Hungary); Szécsényi, I.M. [Department of Mathematical Sciences, Durham University, South Road, Durham, DH1 3LE (United Kingdom); Institute of Theoretical Physics, Eötvös Loránd University,Pázmány Péter sétány 1/A, 1117 Budapest (Hungary); Takács, G. [MTA-BME “Momentum” Statistical Field Theory Research Group,Budafoki út 8, 1111 Budapest (Hungary); Department of Theoretical Physics, Budapest University of Technology and Economics,Budafoki út 8, 1111 Budapest (Hungary)

2015-04-07

We present a conjecture for the exact expression of finite volume expectation values in excited states in integrable quantum field theories, which is an extension of an earlier conjecture to the case of general diagonal factorized scattering with bound states and a nontrivial bootstrap structure. The conjectured expression is a spectral expansion which uses the exact form factors and the excited state thermodynamic Bethe Ansatz as building blocks. The conjecture is proven for the case of the trace of the energy-moment tensor. Concerning its validity for more general operators, we provide numerical evidence using the truncated conformal space approach. It is found that the expansion fails to be well-defined for small values of the volume in cases when the singularity structure of the TBA equations undergoes a non-trivial rearrangement under some critical value of the volume. Despite these shortcomings, the conjectured expression is expected to be valid for all volumes for most of the excited states, and as an expansion above the critical volume for the rest.

Exact finite volume expectation values of local operators in excited states

International Nuclear Information System (INIS)

Pozsgay, B.; Szécsényi, I.M.; Takács, G.

2015-01-01

We present a conjecture for the exact expression of finite volume expectation values in excited states in integrable quantum field theories, which is an extension of an earlier conjecture to the case of general diagonal factorized scattering with bound states and a nontrivial bootstrap structure. The conjectured expression is a spectral expansion which uses the exact form factors and the excited state thermodynamic Bethe Ansatz as building blocks. The conjecture is proven for the case of the trace of the energy-moment tensor. Concerning its validity for more general operators, we provide numerical evidence using the truncated conformal space approach. It is found that the expansion fails to be well-defined for small values of the volume in cases when the singularity structure of the TBA equations undergoes a non-trivial rearrangement under some critical value of the volume. Despite these shortcomings, the conjectured expression is expected to be valid for all volumes for most of the excited states, and as an expansion above the critical volume for the rest.

Polarization and molar volumes of ortho- and para-deuterium solutions

International Nuclear Information System (INIS)

Milenko, Yu.Ya.; Sibileva, R.M.

1976-01-01

The dielectric constant of liquid solutions of ortho-and para-deuterium is measured over the range of 2.2-91% p-D 2 from 18.7 to 20.4deg K. Data on polarization and molar volumes are obtained for the whole (0-100%) concentration range. Corrected summary to paper [2] is also listed: dielectric constant of ortho- and para-hydrogen liquid solution is measured within a concentration range of 0-97% of o-molecules at 14-20.4deg K. It is established that dependence of the Clausius-Mossotti function for o-p-hydrogen solutions of o-p-composition is linear. Molar volumes of the o-p-mixtures are calculated. The excessive molar volumes are found, positive deviation from additivity, 0.15% is established

Mechanical properties of nanosheets and nanotubes investigated using a new geometry independent volume definition

International Nuclear Information System (INIS)

Wagner, Philipp; Ivanovskaya, Viktoria V; Ewels, Christopher P; Rayson, Mark J; Briddon, Patrick R

2013-01-01

Cross-sectional area and volume become difficult to define as material dimensions approach the atomic scale. This limits the transferability of macroscopic concepts such as Young’s modulus. We propose a new volume definition where the enclosed nanosheet or nanotube average electron density matches that of the parent layered bulk material. We calculate the Young’s moduli for various nanosheets (including graphene, BN and MoS 2 ) and nanotubes. Further implications of this new volume definition such as a Fermi level dependent Young’s modulus and out-of-plane Poisson’s ratio are shown. (paper)

Cognitive neuroscience robotics B analytic approaches to human understanding

CERN Document Server

Ishiguro, Hiroshi; Asada, Minoru; Osaka, Mariko; Fujikado, Takashi

2016-01-01

Cognitive Neuroscience Robotics is the first introductory book on this new interdisciplinary area. This book consists of two volumes, the first of which, Synthetic Approaches to Human Understanding, advances human understanding from a robotics or engineering point of view. The second, Analytic Approaches to Human Understanding, addresses related subjects in cognitive science and neuroscience. These two volumes are intended to complement each other in order to more comprehensively investigate human cognitive functions, to develop human-friendly information and robot technology (IRT) systems, and to understand what kind of beings we humans are. Volume B describes to what extent cognitive science and neuroscience have revealed the underlying mechanism of human cognition, and investigates how development of neural engineering and advances in other disciplines could lead to deep understanding of human cognition.

Optimization of self-healing additives dispersity in cement

OpenAIRE

E.R. Ismagilova; F.A. Agzamov; A.J. Abbas

2017-01-01

The article reflects results of the experimental studies on the modifying agent’s dispersion to\\ud affect the nature of its distribution in the total volume of cement stone. An attempt was made to evaluate\\ud the strength and filtration properties of the cement stone with respect to the heterogeneity of its structure.\\ud The effect of a character of the modifying additive distribution on the permeability and strength of the\\ud cement stone was investigated, as a result it was clarified that t...

Choline chloride-based deep eutectic solvents as additives for optimizing chromatographic behavior of caffeic acid

International Nuclear Information System (INIS)

Li, Guizhen; Zhu, Tao; Lei, Yingjie

2015-01-01

A series of deep eutectic solvents (DESs) were prepared using glycerol and choline chloride (ChCl), and Fourier transform infrared spectrometer (FT-IR) was used to analyze the spectra of glycerol, choline chloride and DESs based on glycerol and choline chloride. Then DESs were used as the additives of mobile phase to optimize chromatographic behavior of caffeic acid in high performance liquid chromatography (HPLC). A 17-run Box-Behnken design (BBD) was employed to evaluate effect of DESs as additives by analyzing the maximum theoretical plate number. Three factors, reaction temperature (60 .deg. C, 80 .deg. C, 100 .deg. C), molar ratio of glycerol and choline chloride (2 : 1, 3 : 1, 4 : 1, n/n), and volume percent of additives (0.05%, 0.10%, 0.15%, v/v), were investigated in BBD. The optimum experiment condition was that of reaction temperature (80 .deg. C), molar ratio of glycerol and ChCl (3 : 1, n/n), and volume percent of additive (0.10%, v/v). The mean chromatographic theoretical plate number of the caffeic acid this condition was 1567.5, and DESs as additives shorten the retention time and modify the chromatogram shape, proving DESs as additives for effective theoretical plate number and column efficiency in HPLC.

Choline chloride-based deep eutectic solvents as additives for optimizing chromatographic behavior of caffeic acid

Energy Technology Data Exchange (ETDEWEB)

Li, Guizhen; Zhu, Tao; Lei, Yingjie [Tianjin University of Technology, Tianjin (China)

2015-10-15

A series of deep eutectic solvents (DESs) were prepared using glycerol and choline chloride (ChCl), and Fourier transform infrared spectrometer (FT-IR) was used to analyze the spectra of glycerol, choline chloride and DESs based on glycerol and choline chloride. Then DESs were used as the additives of mobile phase to optimize chromatographic behavior of caffeic acid in high performance liquid chromatography (HPLC). A 17-run Box-Behnken design (BBD) was employed to evaluate effect of DESs as additives by analyzing the maximum theoretical plate number. Three factors, reaction temperature (60 .deg. C, 80 .deg. C, 100 .deg. C), molar ratio of glycerol and choline chloride (2 : 1, 3 : 1, 4 : 1, n/n), and volume percent of additives (0.05%, 0.10%, 0.15%, v/v), were investigated in BBD. The optimum experiment condition was that of reaction temperature (80 .deg. C), molar ratio of glycerol and ChCl (3 : 1, n/n), and volume percent of additive (0.10%, v/v). The mean chromatographic theoretical plate number of the caffeic acid this condition was 1567.5, and DESs as additives shorten the retention time and modify the chromatogram shape, proving DESs as additives for effective theoretical plate number and column efficiency in HPLC.

Fuel spray and combustion characteristics of butanol blends in a constant volume combustion chamber

International Nuclear Information System (INIS)

Liu, Yu; Li, Jun; Jin, Chao

2015-01-01

Highlights: • A sudden drop is observed in spray penetration for B10S10D80 fuel at 800 and 900 K. • With increasing of temperature, auto-ignition timings of fuels become unperceivable. • Low n-butanol addition has little effect on autoignition timings from 800 to 1200 K. • n-Butanol additive can reduce soot emissions at the near-wall regions. • Larger soot reduction is seen at higher ambient temperatures for n-butanol addition. - Abstract: The processes of spray penetrations, flame propagation and soot formation and oxidation fueling n-butanol/biodiesel/diesel blends were experimentally investigated in a constant volume combustion chamber with an optical access. B0S20D80 (0% n-butanol, 20% soybean biodiesel, and 80% diesel in volume) was prepared as the base fuel. n-Butanol was added into the base fuel by volumetric percent of 5% and 10%, denoted as B5S15D80 (5% n-butanol/15% soybean biodiesel/80% diesel) and B10S10D80 (10% n-butanol/10% soybean biodiesel/80% diesel). The ambient temperatures at the time of fuel injection were set to 800 K, 900 K, 1000 K, and 1200 K. Results indicate that the penetration length reduces with the increase of n-butanol volumes in blending fuels and ambient temperatures. The spray penetration presents a sudden drop as fueling B10S10D80 at 800 K and 900 K, which might be caused by micro-explosion. A larger premixed combustion process is observed at low ambient temperatures, while the heat release rate of high ambient temperatures presents mixing controlled diffusion combustion. With a lower ambient temperature, the auto-ignition delay becomes longer with increasing of n-butanol volume in blends. However, with increasing of ambient temperatures, the auto-ignition timing between three fuels becomes unperceivable. Generally, low n-butanol addition has a limited or no effect on the auto-ignition timing in the current conditions. Compared with the base fuel of B0S20D80, n-butanol additive with 5% or 10% in volume can reduce soot

75 FR 42237 - Regulation of Fuels and Fuel Additives: 2011 Renewable Fuel Standards

Science.gov (United States)

2010-07-20

... Based on a Thermochemical Platform 3. Hybrid Thermochemical/Biochemical Processes 4. Pyrolysis and Depolymerization a. Pyrolysis Diesel Fuel and Gasoline b. Catalytic Depolymerization 5. Catalytic Reforming of... result would be that additional volumes of conventional renewable fuel, such as corn-starch ethanol...

Larger amygdala volume in first-degree relatives of patients with major depression

Directory of Open Access Journals (Sweden)

Nina Romanczuk-Seiferth

2014-01-01

Conclusions: Larger gray matter volume in healthy relatives of MDD patients point to a possible vulnerability mechanism in MDD etiology and therefore extend knowledge in the field of high-risk approaches in MDD.

Changes in Upper Airway Volume Following Orthognathic Surgery.

Science.gov (United States)

Marcussen, Lillian; Stokbro, Kasper; Aagaard, Esben; Torkov, Peter; Thygesen, Torben

2017-01-01

Reduced volume of the internal skeletal dimensions of the face is 1 of the main causes of obstructive sleep apnea, and attention to patients' airways is necessary when planning orthognathic treatment. This study aims to describe changes in upper airway volume following virtually planned orthognathic surgery.A retrospective pilot study was designed with 30 randomly selected patients (10 men and 20 women, aged 23.1 ± 6.8 years, molar-relations: 15 neutral, 8 distal, and 7 mesial). Cone-beam computed tomography scans were performed before surgery and 1 week following surgery. The authors did total upper airway volume measurements and obtained 1-mm slices at vertical levels in the velo-, oro-, and hypopharynx and at the smallest visible cross-section.Measurements before and after surgery were compared using Student t test.After orthognathic surgery, the minimum cross-sectional area at the vertical level increased from 83 mm ± 33 before surgery to 102 mm ± 36 after surgery (P = 0.019). In patients with neutral and distal occlusions, the minimum cross-sectional slice volume increased in 87% but in only 57% with mesial occlusion.The present findings suggest that orthognathic surgery increases upper airway volume parameters, but a few patients have continued impairment of the airways following orthognathic surgery. Further studies are needed to confirm an individual surgical planning approach that potentially could bring the minimum cross sectional area out of the risk zone.

Quantification of regional fat volume in rat MRI

Science.gov (United States)

Sacha, Jaroslaw P.; Cockman, Michael D.; Dufresne, Thomas E.; Trokhan, Darren

2003-05-01

Multiple initiatives in the pharmaceutical and beauty care industries are directed at identifying therapies for weight management. Body composition measurements are critical for such initiatives. Imaging technologies that can be used to measure body composition noninvasively include DXA (dual energy x-ray absorptiometry) and MRI (magnetic resonance imaging). Unlike other approaches, MRI provides the ability to perform localized measurements of fat distribution. Several factors complicate the automatic delineation of fat regions and quantification of fat volumes. These include motion artifacts, field non-uniformity, brightness and contrast variations, chemical shift misregistration, and ambiguity in delineating anatomical structures. We have developed an approach to deal practically with those challenges. The approach is implemented in a package, the Fat Volume Tool, for automatic detection of fat tissue in MR images of the rat abdomen, including automatic discrimination between abdominal and subcutaneous regions. We suppress motion artifacts using masking based on detection of implicit landmarks in the images. Adaptive object extraction is used to compensate for intensity variations. This approach enables us to perform fat tissue detection and quantification in a fully automated manner. The package can also operate in manual mode, which can be used for verification of the automatic analysis or for performing supervised segmentation. In supervised segmentation, the operator has the ability to interact with the automatic segmentation procedures to touch-up or completely overwrite intermediate segmentation steps. The operator's interventions steer the automatic segmentation steps that follow. This improves the efficiency and quality of the final segmentation. Semi-automatic segmentation tools (interactive region growing, live-wire, etc.) improve both the accuracy and throughput of the operator when working in manual mode. The quality of automatic segmentation has been

Vitrification of F006 plating waste sludge by Reactive Additive Stabilization Process (RASP)

International Nuclear Information System (INIS)

Martin, H.L.; Jantzen, C.M.; Pickett, J.B.

1994-01-01

Solidification into glass of nickel-on-uranium plating wastewater treatment plant sludge (F006 Mixed Waste) has been demonstrated at the Savannah River She (SRS). Vitrification using high surface area additives, the Reactive Additive Stabilization Process (RASP), greatly enhanced the solubility and retention of heavy metals In glass. The bench-scale tests using RASP achieved 76 wt% waste loading In both soda-lime-silica and borosilicate glasses. The RASP has been Independently verified by a commercial waste management company, and a contract awarded to vitrify the approximately 500,000 gallons of stored waste sludge. The waste volume reduction of 89% will greatly reduce the disposal costs, and delisting of the glass waste is anticipated. This will be the world's first commercial-scale vitrification system used for environmental cleanup of Mixed Waste. Its stabilization and volume reduction abilities are expected to set standards for the future of the waste management Industry

Integrable equations, addition theorems, and the Riemann-Schottky problem

International Nuclear Information System (INIS)

Buchstaber, Viktor M; Krichever, I M

2006-01-01

The classical Weierstrass theorem claims that, among the analytic functions, the only functions admitting an algebraic addition theorem are the elliptic functions and their degenerations. This survey is devoted to far-reaching generalizations of this result that are motivated by the theory of integrable systems. The authors discovered a strong form of the addition theorem for theta functions of Jacobian varieties, and this form led to new approaches to known problems in the geometry of Abelian varieties. It is shown that strong forms of addition theorems arise naturally in the theory of the so-called trilinear functional equations. Diverse aspects of the approaches suggested here are discussed, and some important open problems are formulated.

Estimation of lung volume and pulmonary blood volume from radioisotopic images

International Nuclear Information System (INIS)

Kanazawa, Minoru

1989-01-01

Lung volume and pulmonary blood volume in man were estimated from the radioisotopic image using single photon emission computed tomography (SPECT). Six healthy volunteers were studied in a supine position with normal and altered lung volumes by applying continuous negative body-surface pressure (CNP) and by positive end-expiratory pressure (PEEP). 99m Tc labeled human serum albumin was administered as an aerosol to image the lungs. The CNP caused the diaphragm to be lowered and it increased the mean lung tissue volume obtained by SPECT from 3.09±0.49 l for baseline to 3.67±0.62 l for 10 cmH 2 O (p 2 O (p 2 O), respectively. The PEEP also increased the lung tissue volume to 3.68±0.68 l for 10 cmH 2 O as compared with the baseline (p 2 O PEEP. The lung tissue volume obtained by SPECT showed a positive correlation with functional residual capacity measured by the He dilution method (r=0.91, p 99m Tc-labeled red blood cells. The L/H ratio decreased after either the CNP or PEEP, suggesting a decrease in the blood volume per unit lung volume. However, it was suggested that the total pulmonary blood volume increased slightly either on the CNP (+7.4% for 10 cmH 2 O, p 2 O,p<0.05) when we extrapolated the L/H ratio to the whole lungs by multiplying the lung tissue volume obtained by SPECT. We concluded that SPECT could offer access to the estimation of lung volume and pulmonary blood volume in vivo. (author)

Influence of additive from sugar beet on white bread quality

Directory of Open Access Journals (Sweden)

Filipović Nada K.

2004-01-01

Full Text Available The additive of acceptable sensory, physical and chemical and microbiological characteristics was made from cossettes. Great water binding capacity related to microcrystals of cellulose qualifies this additive as a desired one in bread making process. Bread was baked in the laboratory and patent flour was used. The additive with particles smaller than 95 (m was supplemented in the quantities of 2, 5 and 10%. The data related to the influence of the quantity of additive on white bread quality point that parallel to increasing the amount of the additive in the dough, yield of dough and bread were also increased. Negative effects are detected as volume depression and inferior bread crumb quality and altered crumb color. The decrease in bread quality is small if 2% of additive was applied, but significant with 5 and 10%. The bread freshness was highly graded 48 hours after baking due to the ability of the additive to retain water. On the whole, bread of superior quality supplemented by 5 and 10% of the additive from sugar beet fiber can be easily made by fortifying flour with gluten and by adding appropriate dough conditioner.

Cross-correlations in volume space: Differences between buy and sell volumes

Science.gov (United States)

Lee, Sun Young; Hwang, Dong Il; Kim, Min Jae; Koh, In Gyu; Kim, Soo Yong

2011-03-01

We study the cross-correlations of buy and sell volumes on the Korean stock market in high frequency. We observe that the pulling effects of volumes are as small as that of returns. The properties of the correlations of buy and sell volumes differ. They are explained by the degree of synchronization of stock volumes. Further, the pulling effects on the minimal spanning tree are studied. In minimal spanning trees with directed links, the large pulling effects are clustered at the center, not uniformly distributed. The Epps effect of buy and sell volumes are observed. The reversal of the cross-correlations of buy and sell volumes is also detected.

Cálculo do volume na equação de van der Waals pelo método de cardano Volume calculation in van der Waals equation by the cardano method

Directory of Open Access Journals (Sweden)

Nelson H. T. Lemes

2010-01-01

Full Text Available Analytical solutions of a cubic equation with real coefficients are established using the Cardano method. The method is first applied to simple third order equation. Calculation of volume in the van der Waals equation of state is afterwards established. These results are exemplified to calculate the volumes below and above critical temperatures. Analytical and numerical values for the compressibility factor are presented as a function of the pressure. As a final example, coexistence volumes in the liquid-vapor equilibrium are calculated. The Cardano approach is very simple to apply, requiring only elementary operations, indicating an attractive method to be used in teaching elementary thermodynamics.

Input/Output: hoeveelheid en volume compost in de champignonkweek

NARCIS (Netherlands)

Leyh, Romain; Blok, Chris

2017-01-01

The conclusion of a previous experiment showed that the compost quantity was the most determining parameter for the production volume of mushrooms, despite the addition of hemi cellulose as carbon source to the compost. The present experiment focuses on the mycelium action with regard to the carbon

77 FR 16784 - E. & J. Gallo Winery; Filing of Color Additive Petition

Science.gov (United States)

2012-03-22

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration 21 CFR Part 73 [Docket No. FDA-2012-C-0224] E. & J. Gallo Winery; Filing of Color Additive Petition AGENCY: Food and Drug... volume but not including distilled spirits mixtures containing more that 5% wine on a proof gallon basis...

Updated Drainable Interstitial Liquid Volume Estimates for 119 Single Shell Tanks (SST) Declared Stabilized

International Nuclear Information System (INIS)

FIELD, J.G.

2000-01-01

This document assesses the volume of drainable interstitial liquid (DIL) and pumpable liquid remaining in 119 single-shell tanks (SSTs) that were previously stabilized. Based on the methodology and assumptions presented, the DIL exceeded the stabilization criterion of less than 50,000 gal in two of the 119 SSTs. Tank 241-C-102 had an estimated DIL of 62,000 gal, and the estimated DIL for tank 241-BY-103 was 58,000 gal. In addition, tanks 241-BX-103, 241-T-102, and 241-T-112 appear to exceed the stabilization criterion of 5,000 gal supernatant. An assessment of the source of the supernatant in these tanks is beyond the scope of this document. The actual DIL and pumpable liquid remaining volumes for each tank may vary significantly from estimated volumes as a result of specific tank waste characteristics that are not currently measured or defined. Further refinement to the pumpable liquid and DIL volume estimates may be needed as additional tank waste information is obtained

Computing and Visualizing Reachable Volumes for Maneuvering Satellites

Science.gov (United States)

Jiang, M.; de Vries, W.; Pertica, A.; Olivier, S.