WorldWideScience

Sample records for volume additivity approach

  1. Does the Addition of Inert Gases at Constant Volume and Temperature Affect Chemical Equilibrium?

    Science.gov (United States)

    Paiva, Joao C. M.; Goncalves, Jorge; Fonseca, Susana

    2008-01-01

    In this article we examine three approaches, leading to different conclusions, for answering the question "Does the addition of inert gases at constant volume and temperature modify the state of equilibrium?" In the first approach, the answer is yes as a result of a common students' alternative conception; the second approach, valid only for ideal…

  2. Does the Addition of Inert Gases at Constant Volume and Temperature Affect Chemical Equilibrium?

    Science.gov (United States)

    Paiva, Joao C. M.; Goncalves, Jorge; Fonseca, Susana

    2008-01-01

    In this article we examine three approaches, leading to different conclusions, for answering the question "Does the addition of inert gases at constant volume and temperature modify the state of equilibrium?" In the first approach, the answer is yes as a result of a common students' alternative conception; the second approach, valid only for ideal…

  3. Cost-Efficient Low-Volume Production Through Additive Manufacturing

    OpenAIRE

    Solberg, Steffen

    2016-01-01

    Additive manufacturing, commonly known as 3D Printing, is a production method of rising popularity. The method works by adding layers of material, in contrast to subtracting, which is the dominating method today. The objective of this thesis has been to evaluate the cost-efficiency of producing relatively complex parts through additive manufacturing, compared to subtractive methods with production volumes less than 20 units. Initial findings narrow the additive methods down ...

  4. Cost-Efficient Low-Volume Production Through Additive Manufacturing

    OpenAIRE

    Solberg, Steffen

    2016-01-01

    Additive manufacturing, commonly known as 3D Printing, is a production method of rising popularity. The method works by adding layers of material, in contrast to subtracting, which is the dominating method today. The objective of this thesis has been to evaluate the cost-efficiency of producing relatively complex parts through additive manufacturing, compared to subtractive methods with production volumes less than 20 units. Initial findings narrow the additive methods down ...

  5. Combined additive manufacturing approaches in tissue engineering.

    Science.gov (United States)

    Giannitelli, S M; Mozetic, P; Trombetta, M; Rainer, A

    2015-09-01

    Advances introduced by additive manufacturing (AM) have significantly improved the control over the microarchitecture of scaffolds for tissue engineering. This has led to the flourishing of research works addressing the optimization of AM scaffolds microarchitecture to optimally trade-off between conflicting requirements (e.g. mechanical stiffness and porosity level). A fascinating trend concerns the integration of AM with other scaffold fabrication methods (i.e. "combined" AM), leading to hybrid architectures with complementary structural features. Although this innovative approach is still at its beginning, significant results have been achieved in terms of improved biological response to the scaffold, especially targeting the regeneration of complex tissues. This review paper reports the state of the art in the field of combined AM, posing the accent on recent trends, challenges, and future perspectives.

  6. Development of volume deposition on cast iron by additive manufacturing

    Energy Technology Data Exchange (ETDEWEB)

    Niyanth S, Niyanth [ORNL; Dehoff, Ryan R [ORNL; Jordan, Brian H [ORNL; Babu, Suresh S. [University of Tennessee (UTK) and Oak Ridge National Laboratory (ORNL)

    2016-11-10

    ORNL partnered with Cummins to demonstrate the feasibility of using additive manufacturing techniques to help develop repair techniques for refurbished cast iron engine blocks. Cummins is interested in the refurbished engine business due to the increased cost savings and reduced emissions. It is expected that by refurbishing engines could help reduce the green house gas emissions by as much as 85%. Though such repair techniques are possible in principle there has been no major industry in the automotive sector that has deployed this technology. Therefore phase-1 would seek to evaluate the feasibility of using the laser directed energy deposition technique to repair cast iron engine blocks. The objective of the phase-1 would be to explore various strategies and understand the challenges involved. During phase-1 deposits were made using Inconel-718, Nickel, Nr-Cr-B braze filler. Inconel 718 builds showed significant cracking in the heat-affected zone in the cast iron. Nickel was used to reduce the cracking in the cast iron substrate, however the Ni builds did not wet the substrate sufficiently resulting in poor dimensional tolerance. In order to increase wetting the Ni was alloyed with the Ni-Cr-B braze to decrease the surface tension of Ni. This however resulted in significant cracks in the build due to shrinkage stresses associated with multiple thermal cycling. Hence to reduce the residual stresses in the builds the DMD-103D equipment was modified and the cast iron block was pre heated using cartridge heaters. Inconel-718 alloyed with Ni was deposited on the engine block. The pre-heated deposits showed a reduced susceptibility to cracking. If awarded the phase-2 of the project would aim to develop process parameters to achieve a crack free deposit engine block.

  7. A Novel Approach for Evaluating Carbamate Mixtures for Dose Additivity

    Science.gov (United States)

    Two mathematical approaches were used to test the hypothesis ofdose-addition for a binary and a seven-chemical mixture ofN-methyl carbamates, toxicologically similar chemicals that inhibit cholinesterase (ChE). In the more novel approach, mixture data were not included in the ana...

  8. A new DFM approach to combine machining and additive manufacturing

    CERN Document Server

    Kerbrat, Olivier; Hascoët, Jean-Yves; 10.1016/j.compind.2011.04.003

    2011-01-01

    Design For Manufacturing (DFM) approaches aim to integrate manufacturability aspects during the design stage. Most of DFM approaches usually consider only one manufacturing process, but products competitiveness may be improved by designing hybrid modular products, in which products are seen as 3-D puzzles with modules realized aside by the best manufacturing process and further gathered. A new DFM system is created in order to give quantitative information during the product design stage of which modules will benefit in being machined and which ones will advantageously be realized by an additive process (such as Selective Laser Sintering or laser deposition). A methodology for a manufacturability evaluation in case of a subtractive or an additive manufacturing process is developed and implemented in a CAD software. Tests are carried out on industrial products from automotive industry.

  9. Analysing inequalities in Germany a structured additive distributional regression approach

    CERN Document Server

    Silbersdorff, Alexander

    2017-01-01

    This book seeks new perspectives on the growing inequalities that our societies face, putting forward Structured Additive Distributional Regression as a means of statistical analysis that circumvents the common problem of analytical reduction to simple point estimators. This new approach allows the observed discrepancy between the individuals’ realities and the abstract representation of those realities to be explicitly taken into consideration using the arithmetic mean alone. In turn, the method is applied to the question of economic inequality in Germany.

  10. Kinetics approach to modeling of polymer additive degradation in lubricants

    Institute of Scientific and Technical Information of China (English)

    llyaI.KUDISH; RubenG.AIRAPETYAN; Michael; J.; COVITCH

    2001-01-01

    A kinetics problem for a degrading polymer additive dissolved in a base stock is studied.The polymer degradation may be caused by the combination of such lubricant flow parameters aspressure, elongational strain rate, and temperature as well as lubricant viscosity and the polymercharacteristics (dissociation energy, bead radius, bond length, etc.). A fundamental approach tothe problem of modeling mechanically induced polymer degradation is proposed. The polymerdegradation is modeled on the basis of a kinetic equation for the density of the statistical distribu-tion of polymer molecules as a function of their molecular weight. The integrodifferential kineticequation for polymer degradation is solved numerically. The effects of pressure, elongational strainrate, temperature, and lubricant viscosity on the process of lubricant degradation are considered.The increase of pressure promotes fast degradation while the increase of temperature delaysdegradation. A comparison of a numerically calculated molecular weight distribution with an ex-perimental one obtained in bench tests showed that they are in excellent agreement with eachother.

  11. Modeling Approach for Estimating Co-Produced Water Volumes and Saltwater Disposal Volumes in Oklahoma

    Science.gov (United States)

    Murray, K. E.

    2016-12-01

    Management of produced fluids has become an important issue in Oklahoma because large volumes of saltwater are co-produced with oil and gas, and disposed into saltwater disposal wells at high rates. Petroleum production increased from 2009-2015, especially in central and north-central Oklahoma where the Mississippian and Hunton zones were redeveloped using horizontal wells and dewatering techniques that have led to a disproportional increase in produced water volumes. Improved management of co-produced water, including desalination for beneficial reuse and decreased saltwater disposal volumes, is only possible if spatial and temporal trends can be defined and related to the producing zones. It is challenging to quantify the volumes of co-produced water by region or production zone because co-produced water volumes are generally not reported. Therefore, the goal of this research is to estimate co-produced water volumes for 2008-present with an approach that can be replicated as petroleum production shifts to other regions. Oil and gas production rates from subsurface zones were multiplied by ratios of H2O:oil and H2O:gas for the respective zones. Initial H2O:oil and H2O:gas ratios were adjusted/calibrated, by zone, to maximize correlation of county-scale produced H2O estimates versus saltwater disposal volumes from 2013-2015. These calibrated ratios were then used to compute saltwater disposal volumes from 2008-2012 because of apparent data gaps in reported saltwater disposal volumes during that timeframe. This research can be used to identify regions that have the greatest need for produced water treatment systems. The next step in management of produced fluids is to explore optimal energy-efficient strategies that reduce deleterious effects.

  12. Efficient volume preserving approach for skeleton-based implicit surfaces

    Institute of Scientific and Technical Information of China (English)

    史红兵; 童若锋; 董金祥

    2003-01-01

    This paper presents an efficient way to preserve the volume of implicit surfaces generated by skeletons. Recursive subdivision is used to efficiently calculate the volume. The criterion for subdivision is obtained by using the property of density functions and treating different types of skeletons respectively to get accurate minimum and maximum distances from a cube to a skeleton. Compared with the criterion generated by other ways such as using traditional Interval Analysis, Affine Arithmetic, or Lipschitz condition, our approach is much better both in speed and accuracy.

  13. Morphological study of transpterional-insula approach using volume rendering.

    Science.gov (United States)

    Jia, Linpei; Su, Lue; Sun, Wei; Wang, Lina; Yao, Jihang; Li, Youqiong; Luo, Qi

    2012-11-01

    This study describes the measurements of inferior circular insular sulcus (ICIS) and the shortest distance from ICIS to the temporal horn and determines the position of the incision, which does less harm to the temporal stem in the transpterional-insula approach using volume-rendering technique. Results of the research showed that one-third point over the anterior side of ICIS may be the ideal penetration point during operation. And there is no difference between 2 hemispheres (P ICIS from other Chinese researches demonstrated that volume rendering is a reliable method in insular research that enables mass measurements.

  14. Drug and Alcohol Studies (Volume 4: Policy approaches)

    OpenAIRE

    Macgregor, S.; Thom, B

    2014-01-01

    VOLUME FOUR: POLICY APPROACHES Preface Robert MacCoun and Peter Reuter The Varieties of Drug Control at the Dawn of the 21st Century Comparative Analysis of Alcohol Control Policies in 30 Countries Donald Brand et al A Comparative Study of 38 European Countries Limited Rationality and the Limits of Supply Reduction Jonathan Caulkins and Robert MacCoun The Limited Relevance of Drug Policy Craig Reinerman, Peter Cohen and Hendrien Kaal Cannabis in Amsterdam and San Francisco AIDS and Injecting ...

  15. The Algebraic versus the Topological Approach to Additive Representations

    NARCIS (Netherlands)

    Wakker, P.P.

    1988-01-01

    It is proved that, under a nontriviality assumption, an additive function on a Cartesian product of connected topological spaces is continuous, whenever the preference relation, represented by this function, is continuous. The result is used to generalize a theorem of Debreu (1960) on additive repre

  16. A new DFM approach to combine machining and additive manufacturing

    OpenAIRE

    Kerbrat, Olivier; MOGNOL, Pascal; Hascoët, Jean-Yves

    2011-01-01

    International audience; Design For Manufacturing (DFM) approaches aim to integrate manufacturability aspects during the design stage. Most of DFM approaches usually consider only one manufacturing process, but products competitiveness may be improved by designing hybrid modular products, in which products are seen as 3-D puzzles with modules realized aside by the best manufacturing process and further gathered. A new DFM system is created in order to give quantitative information during the p...

  17. A new DFM approach to combine machining and additive manufacturing

    OpenAIRE

    Kerbrat, Olivier; Mognol, Pascal; Hascoët, Jean-Yves

    2011-01-01

    International audience; Design For Manufacturing (DFM) approaches aim to integrate manufacturability aspects during the design stage. Most of DFM approaches usually consider only one manufacturing process, but products competitiveness may be improved by designing hybrid modular products, in which products are seen as 3-D puzzles with modules realized aside by the best manufacturing process and further gathered. A new DFM system is created in order to give quantitative information during the p...

  18. Additive manufacturing approaches for stress relief in semiconductor die packaging

    NARCIS (Netherlands)

    Zon, C.M.B. van der; Wiel, A. van der; Maalderink, H.H.; Vaes, M.H.E.; Aulbers, A.P.; Vorst, L.T.G. van de; Cate, A.T. ten; Furrer, J.F.; Burssens, J.W.; Chen, J.

    2012-01-01

    Packaging of semiconductor chips, especially MEMS-based, always causes stress on the functional areas of the die causing unpredictable changes in chip performance. As a consequence such devices can only be calibrated individually after complete assembly. Melexis and TNO have developed an approach to

  19. Additive manufacturing approaches for stress relief in semiconductor die packaging

    NARCIS (Netherlands)

    Zon, C.M.B. van der; Wiel, A. van der; Maalderink, H.H.; Vaes, M.H.E.; Aulbers, A.P.; Vorst, L.T.G. van de; Cate, A.T. ten; Furrer, J.F.; Burssens, J.W.; Chen, J.

    2012-01-01

    Packaging of semiconductor chips, especially MEMS-based, always causes stress on the functional areas of the die causing unpredictable changes in chip performance. As a consequence such devices can only be calibrated individually after complete assembly. Melexis and TNO have developed an approach to

  20. Planning Additions to Academic Library Buildings: A Seamless Approach.

    Science.gov (United States)

    Hawthorne, Pat, Ed.; Martin, Ron G., Ed.

    This document presents three case studies that illustrate how library staffs and architectural design teams can work together to plan additions that are successful solutions to building problems. The case studies cover the experiences of Hope College, Holland, Michigan (David Jensen, Margaret Jensen), Western Maryland College, Westminster,…

  1. The Algebraic versus the Topological Approach to Additive Representations

    NARCIS (Netherlands)

    P.P. Wakker (Peter)

    1988-01-01

    textabstractIt is proved that, under a nontriviality assumption, an additive function on a Cartesian product of connected topological spaces is continuous, whenever the preference relation, represented by this function, is continuous. The result is used to generalize a theorem of Debreu ((1960). Mat

  2. Additive Biomanufacturing: An Advanced Approach for Periodontal Tissue Regeneration.

    Science.gov (United States)

    Carter, Sarah-Sophia D; Costa, Pedro F; Vaquette, Cedryck; Ivanovski, Saso; Hutmacher, Dietmar W; Malda, Jos

    2017-01-01

    Periodontitis is defined as a chronic inflammatory condition, characterized by destruction of the periodontium, composed of hard (i.e. alveolar bone and cementum) and soft tissues (i.e. gingiva and periodontal ligament) surrounding and supporting the teeth. In severe cases, reduced periodontal support can lead to tooth loss, which requires tissue augmentation or procedures that initiate a repair, yet ideally a regenerative response. However, mimicking the three-dimensional complexity and functional integration of the different tissue components via scaffold- and/or matrix-based guided tissue engineering represents a great challenge. Additive biomanufacturing, a manufacturing method in which objects are designed and fabricated in a layer-by-layer manner, has allowed a paradigm shift in the current manufacturing of medical devices and implants. This shift from design-to-manufacture to manufacture-to-design, seen from a translational research point of view, provides the biomedical engineering and periodontology communities a technology with the potential to achieve tissue regeneration instead of repair. In this review, the focus is put on additively biomanufactured scaffolds for periodontal applications. Besides a general overview of the concept of additive biomanufacturing within this field, different developed scaffold designs are described. To conclude, future directions regarding advanced biomaterials and additive biomanufacturing technologies for applications in regenerative periodontology are highlighted.

  3. A direct renormalization group approach for the excluded volume problem

    Science.gov (United States)

    de Queiroz, S. L. A.; Chaves, C. M.

    1980-03-01

    We propose a position-space renormalization group approach for the excluded volume problem in a square lattice by considering “percolating” self-avoiding paths in a b×b cell, where b=2,3,4: Two ways of counting the paths are presented. The values obtained for the exponent v converge respectively to 0.731 and 0.720, close to the usually accepted value v=0.75. Comments on the relation between percolation and self-avoiding walks are made.

  4. Weighted Additive Fuzzy Goal Programming Approach to Aggregate Production Planning

    Directory of Open Access Journals (Sweden)

    Mohammed. Mekidiche

    2013-03-01

    Full Text Available This study presents a new formulation of Weighted Additive fuzzy goal programming model developed by Yaghoobi and Tamiz [21]. and Yaghoobi et al [22] for aggregate production planning (WAFGP-APP, The proposed formulation attempts to minimize total production and work force costs, carrying inventory costs and rates of changes in Work force. A real-world industrial case study demonstrates applicability of proposed model to practical APP decision problems. LINGO computer package has been used to solve final crisp linear programming problem package and getting optimal production plan.

  5. A multi-criteria approach to camera motion design for volume data animation.

    Science.gov (United States)

    Hsu, Wei-Hsien; Zhang, Yubo; Ma, Kwan-Liu

    2013-12-01

    We present an integrated camera motion design and path generation system for building volume data animations. Creating animations is an essential task in presenting complex scientific visualizations. Existing visualization systems use an established animation function based on keyframes selected by the user. This approach is limited in providing the optimal in-between views of the data. Alternatively, computer graphics and virtual reality camera motion planning is frequently focused on collision free movement in a virtual walkthrough. For semi-transparent, fuzzy, or blobby volume data the collision free objective becomes insufficient. Here, we provide a set of essential criteria focused on computing camera paths to establish effective animations of volume data. Our dynamic multi-criteria solver coupled with a force-directed routing algorithm enables rapid generation of camera paths. Once users review the resulting animation and evaluate the camera motion, they are able to determine how each criterion impacts path generation. In this paper, we demonstrate how incorporating this animation approach with an interactive volume visualization system reduces the effort in creating context-aware and coherent animations. This frees the user to focus on visualization tasks with the objective of gaining additional insight from the volume data.

  6. New Approach for Error Reduction in the Volume Penalization Method

    CERN Document Server

    Iwakami-Nakano, Wakana; Hatakeyama, Nozomu; Hattori, Yuji

    2012-01-01

    The volume penalization method offers an efficient way to numerically simulate flows around complex-shaped bodies which move and/or deform in general. In this method a penalization term which has permeability eta and a mask function is added to a governing equation as a forcing term in order to impose different dynamics in solid and fluid regions. In this paper we investigate the accuracy of the volume penalization method in detail. We choose the one-dimensional Burgers' equation as a governing equation since it enables us extensive study and it has a nonlinear term similar to the Navier-Stokes equations. It is confirmed that the error which consists of the discretization/truncation error, the penalization error, the round-off error, and others has the same features as those in previous results when we use the standard definition of the mask function. As the number of grid points increases, the error converges to a non-zero constant which is equal to the penalization error. We propose a new approach for reduc...

  7. Frost Formation: Optimizing solutions under a finite volume approach

    Science.gov (United States)

    Bartrons, E.; Perez-Segarra, C. D.; Oliet, C.

    2016-09-01

    A three-dimensional transient formulation of the frost formation process is developed by means of a finite volume approach. Emphasis is put on the frost surface boundary condition as well as the wide range of empirical correlations related to the thermophysical and transport properties of frost. A study of the numerical solution is made, establishing the parameters that ensure grid independence. Attention is given to the algorithm, the discretised equations and the code optimization through dynamic relaxation techniques. A critical analysis of four cases is carried out by comparing solutions of several empirical models against tested experiments. As a result, a discussion on the performance of such parameters is started and a proposal of the most suitable models is presented.

  8. 76 FR 42160 - Allocation of Additional Fiscal Year (FY) 2011 In-Quota Volume for Raw Cane Sugar

    Science.gov (United States)

    2011-07-18

    ... TRADE REPRESENTATIVE Allocation of Additional Fiscal Year (FY) 2011 In-Quota Volume for Raw Cane Sugar... additional fiscal year (FY) 2011 in-quota quantity of the tariff-rate quota (TRQ) for imported raw cane sugar... the United States (HTS), the United States maintains TRQs for imports of raw cane and refined sugar...

  9. 75 FR 26316 - Allocation of Additional Fiscal Year (FY) 2010 In-Quota Volume for Raw Cane Sugar

    Science.gov (United States)

    2010-05-11

    ... TRADE REPRESENTATIVE Allocation of Additional Fiscal Year (FY) 2010 In-Quota Volume for Raw Cane Sugar... additional fiscal year (FY) 2010 in-quota quantity of the tariff-rate quota (TRQ) for imported raw cane sugar... maintains TRQs for imports of raw cane and refined sugar. Section 404(d)(3) of the Uruguay Round Agreements...

  10. The effects of intracranial volume adjustment approaches on multiple regional MRI volumes in healthy aging and Alzheimer’s disease

    Directory of Open Access Journals (Sweden)

    Olga eVoevodskaya

    2014-10-01

    Full Text Available In neurodegeneration research, normalization of regional volumes by intracranial volume (ICV is important to estimate the extent of disease-driven atrophy. There is little agreement as to whether raw volumes, volume-to-ICV fractions or regional volumes from which the ICV factor has been regressed out should be used for volumetric brain imaging studies. Using multiple regional cortical and subcortical volumetric measures generated by Freesurfer (51 in total, the main aim of this study was to elucidate the implications of these adjustment approaches. Magnetic resonance imaging (MRI data were analyzed from two large cohorts, the population-based PIVUS cohort (N=406, all subjects age 75 and the Alzheimer disease Neuroimaging Initiative (ADNI cohort (N=724. Further, we studied whether the chosen ICV normalization approach influenced the relationship between hippocampus and cognition in the three diagnostic groups of the ADNI cohort (Alzheimer’s disease, mild cognitive impairment and healthy individuals. The ability of raw vs adjusted hippocampal volumes to predict diagnostic status was also assessed. In both cohorts raw volumes correlate positively with ICV, but do not scale directly proportionally with it. The correlation direction is reversed for all volume-to-ICV fractions, except the lateral and third ventricles. Most grey matter fractions are larger in females, while lateral ventricle fractions are greater in males. Residual correction effectively eliminated the correlation between the regional volumes and ICV and removed gender differences. The association between hippocampal volumes and cognition was not altered by ICV normalization. Comparing prediction of diagnostic status using the different approaches, small but significant differences were found. The choice of normalization approach should be carefully considered when designing a volumetric brain imaging study.

  11. Liposome-based liquid handling platform featuring addition, mixing, and aliquoting of femtoliter volumes.

    Directory of Open Access Journals (Sweden)

    Hideaki Shiomi

    Full Text Available This paper describes the utilization of giant unilamellar vesicles (GUVs as a platform for handling chemical and biochemical reagents. GUVs with diameters of 5 to 10 µm and containing chemical/biochemical reagents together with inert polymers were fused with electric pulses (electrofusion. After reagent mixing, the fused GUVs spontaneously deformed to a budding shape, separating the mixed solution into sub-volumes. We utilized a microfluidic channel and optical tweezers to select GUVs of interest, bring them into contact, and fuse them together to mix and aliquot the reaction product. We also show that, by lowering the ambient temperature close to the phase transition temperature Tm of the lipid used, daughter GUVs completely detached (fission. This process performs all the liquid-handing features used in bench-top biochemistry using the GUV, which could be advantageous for the membrane-related biochemical assays.

  12. CADDIS Volume 4. Data Analysis: Selecting an Analysis Approach

    Science.gov (United States)

    An approach for selecting statistical analyses to inform causal analysis. Describes methods for determining whether test site conditions differ from reference expectations. Describes an approach for estimating stressor-response relationships.

  13. Price dynamics and trading volume: A semiparametric approach

    NARCIS (Netherlands)

    Spierdijk, L.; Nijman, T.E.; van Soest, A.H.O.

    2004-01-01

    In this paper we investigate the relation between price impact and trading volume for a sample of stocks listed on the New York Stock Exchange. The parametric VAR-models that have been used in the literature impose strong proportionality and symmetry restrictions on the price impact of trades,

  14. Volumes of Solids of Revolution. A Unified Approach

    CERN Document Server

    Martín-Morales, Jorge

    2012-01-01

    We present a method to compute the volume of a solid of revolution as a double integral in a very simple way. Then, we see that the classical methods (disks and shells) are recovered if this double integral is computed by each of the two possible applications of Fubini's theorem. As a further application we also show how Pappus' theorem is obtained from our formula.

  15. Additional experiments on flowability improvements of aviation fuels at low temperatures, volume 2

    Science.gov (United States)

    Stockemer, F. J.; Deane, R. L.

    1982-01-01

    An investigation was performed to study flow improver additives and scale-model fuel heating systems for use with aviation hydrocarbon fuel at low temperatures. Test were performed in a facility that simulated the heat transfer and temperature profiles anticipated in wing fuel tanks during flight of long-range commercial aircraft. The results are presented of experiments conducted in a test tank simulating a section of an outer wing integral fuel tank approximately full-scale in height, chilled through heat exchange panels bonded to the upper and lower horizontal surfaces. A separate system heated lubricating oil externally by a controllable electric heater, to transfer heat to fuel pumped from the test tank through an oil-to-fuel heat exchanger, and to recirculate the heated fuel back to the test tank.

  16. Then and Now: Approaches to Understanding Children's Literature in Two Volumes

    Directory of Open Access Journals (Sweden)

    Baker M Bani-Khair

    2016-06-01

    Full Text Available This research paper investigates two main volumes taken from Children's Literature Association Quarterly; the earlier one is Vol. 11 published in 1986, and the other one, a more recent one, Vol. 32 published in 2007, as to understand the differences and similarities regarding the approaches used in the articles to understand Children's Literature in terms of its multifarious aspects such us, literary genres, styles, themes, and methodologies. Such kind of comparison yielded that those differences between those two volumes cover new thematic suggestions, new treatment and projection of characters, and strict scholarship which make the newer volume different in terms of approaches from the earlier one. The research also concluded that modern analytical perspectives are probably the most obvious transformations and changes in the second volume. Keywords: Volume, approach, childhood, construction, scholarship, transformation, modernism, historicism, analysis

  17. An element-based finite-volume method approach for naturally fractured compositional reservoir simulation

    Energy Technology Data Exchange (ETDEWEB)

    Marcondes, Francisco [Federal University of Ceara, Fortaleza (Brazil). Dept. of Metallurgical Engineering and Material Science], e-mail: marcondes@ufc.br; Varavei, Abdoljalil; Sepehrnoori, Kamy [The University of Texas at Austin (United States). Petroleum and Geosystems Engineering Dept.], e-mails: varavei@mail.utexas.edu, kamys@mail.utexas.edu

    2010-07-01

    An element-based finite-volume approach in conjunction with unstructured grids for naturally fractured compositional reservoir simulation is presented. In this approach, both the discrete fracture and the matrix mass balances are taken into account without any additional models to couple the matrix and discrete fractures. The mesh, for two dimensional domains, can be built of triangles, quadrilaterals, or a mix of these elements. However, due to the available mesh generator to handle both matrix and discrete fractures, only results using triangular elements will be presented. The discrete fractures are located along the edges of each element. To obtain the approximated matrix equation, each element is divided into three sub-elements and then the mass balance equations for each component are integrated along each interface of the sub-elements. The finite-volume conservation equations are assembled from the contribution of all the elements that share a vertex, creating a cell vertex approach. The discrete fracture equations are discretized only along the edges of each element and then summed up with the matrix equations in order to obtain a conservative equation for both matrix and discrete fractures. In order to mimic real field simulations, the capillary pressure is included in both matrix and discrete fracture media. In the implemented model, the saturation field in the matrix and discrete fractures can be different, but the potential of each phase in the matrix and discrete fracture interface needs to be the same. The results for several naturally fractured reservoirs are presented to demonstrate the applicability of the method. (author)

  18. Complex esthetic and functional rehabilitation with an additive, minimally invasive restorative approach.

    Science.gov (United States)

    Ho, Christopher Ck

    2014-06-01

    Historically, the management of patients presenting with extensive tooth wear comprised the use of conventional fixed prosthodontics, an approach that often entailed invasive dentistry and increased biomechanical risk. With the development of adhesive bonding, a dentition can be restored in a much more conservative manner using an additive approach. This case report describes the concepts employed in a complex rehabilitation involving tooth erosion, applying both direct and indirect restorations with minimal biological risk to the patient.

  19. Generalized Navier Boundary Condition for a Volume Of Fluid approach using a Finite-Volume method

    CERN Document Server

    Boelens, A M P

    2016-01-01

    In this work, an analytical Volume Of Fluid (VOF) implementation of the Generalized Navier Boundary Condition is presented based on the Brackbill surface tension model. The model is validated by simulations of droplets on a smooth surface in a planar geometry. Looking at the static behavior of the droplets, it is found that there is a good match between the droplet shape resolved in the simulations and the theoretically predicted shape for various values of the Young's angle. Evaluating the spreading of a droplet on a completely wetting surface, the Voinov-Tanner-Cox law ($\\theta \\propto \\text{Ca}^{1/3}$) can be observed. At later times scaling follows $r \\propto t^{1/2}$, suggesting spreading is limited by inertia. These observations are made without any fitting parameters except the slip length.

  20. Volume-area scaling approach versus flowline model in glacier volume projections

    NARCIS (Netherlands)

    Radic, V.; Hock, Regine; Oerlemans, J.

    2007-01-01

    Volume–area scaling provides a practical alternative to ice-flow modelling to account for glacier size changes when modelling the future evolution of glaciers; however, uncertainties remain as to the validity of this approach under non-steady conditions. We address these uncertainties by deriving sc

  1. "Combining equity and utilitarianism"-additional insights into a novel approach

    NARCIS (Netherlands)

    Lemmen-Gerdessen, van Joke; Kanellopoulos, Argyris; Claassen, Frits

    2017-01-01

    Recently, a novel approach (to be referred to as CEU) was introduced for the frequently arising problem of combining the conflicting criteria of equity and utilitarianism. This paper provides additional insights into CEU and assesses its added value for practice by comparing it with a commonly

  2. A novel approach to predict the excess volume of hydrocarbon mixtures

    NARCIS (Netherlands)

    Finkers, H. J.; Bosma, J. C.; Broekhuis, A. A.

    2011-01-01

    This paper explores whether principles obtained for the packing of solid macroscopic particles can be applied to the study of excess volumes of liquid mixtures. The approach is applied to mixtures of 'pure' hydrocarbons, i.e. containing only C- and H-atoms. In this new approach a set of equations wa

  3. Lattice approach to finite volume form-factors of the Massive Thirring (Sine-Gordon) model

    Science.gov (United States)

    Hegedűs, Árpád

    2017-08-01

    In this paper we demonstrate, that the light-cone lattice approach for the Massive-Thirring (sine-Gordon) model, through the quantum inverse scattering method, admits an appropriate framework for computing the finite volume form-factors of local operators of the model. In this work we compute the finite volume diagonal matrix elements of the U(1) conserved current in the pure soliton sector of the theory. Based on the systematic large volume expansion of our results, we conjecture an exact expression for the finite volume expectation values of local operators in pure soliton states. At large volume in leading order these expectation values have the same form as in purely elastic scattering theories, but exponentially small corrections differ from previous Thermodynamic Bethe Ansatz conjectures of purely elastic scattering theories.

  4. Probabilistic Fuzzy Goal Programming Problems Involving Pareto Distribution: Some Additive Approaches

    Directory of Open Access Journals (Sweden)

    S.K. Barik

    2015-06-01

    Full Text Available In many real-life decision making problems, probabilistic fuzzy goal programming problems are used where some of the input parameters of the problem are considered as random variables with fuzzy aspiration levels. In the present paper, a linearly constrained probabilistic fuzzy goal programming programming problem is presented where the right hand side parameters in some constraints follows Pareto distribution with known mean and variance. Also the aspiration levels are considered as fuzzy. Further, simple, weighted, and preemptive additive approaches are discussed for probabilistic fuzzy goal programming model. These additive approaches are employed to aggregating the membership values and form crisp equivalent deterministic models. The resulting models are then solved by using standard linear mathematical programming techniques. The developed methodology and solution procedures are illustrated with a numerical example.

  5. Infill Optimization for Additive Manufacturing -- Approaching Bone-like Porous Structures.

    Science.gov (United States)

    Wu, Jun; Aage, Niels; Westermann, Ruediger; Sigmund, Ole

    2017-01-23

    Porous structures such as trabecular bone are widely seen in nature. These structures are lightweight and exhibit strong mechanical properties. In this paper, we present a method to generate bone-like porous structures as lightweight infill for additive manufacturing. Our method builds upon and extends voxel-wise topology optimization. In particular, for the purpose of generating sparse yet stable structures distributed in the interior of a given shape, we propose upper bounds on the localized material volume in the proximity of each voxel in the design domain. We then aggregate the local per-voxel constraints by their p-norm into an equivalent global constraint, in order to facilitate an efficient optimization process. Implemented on a high-resolution topology optimization framework, our results demonstrate mechanically optimized, detailed porous structures which mimic those found in nature. We further show variants of the optimized structures subject to different design specifications, and we analyze the optimality and robustness of the obtained structures.

  6. Infill Optimization for Additive Manufacturing - Approaching Bone-like Porous Structures

    DEFF Research Database (Denmark)

    Wu, Jun; Aage, Niels; Westermann, Ruediger

    2017-01-01

    Porous structures such as trabecular bone are widely seen in nature. These structures exhibit superior mechanical properties whilst being lightweight. In this paper, we present a method to generate bone-like porous structures asl ightweight infill for additive manufacturing. Our method builds upon...... and extends voxel-wise topology optimization. In particular, for the purpose of generating sparse yet stable structures distributed in the interior of a given shape, we propose upper bounds on the localized material volume in the proximity of each voxel in the design domain. We then aggregate the local per......-voxel constraints by their p-norm into an equivalent global constraint, in order to facilitate an efficient optimization process. Implemented on a high-resolution topology optimization framework, our results demonstrate mechanically optimized, detailed porous structures which mimic those found innature. We further...

  7. A Hybrid 3D Learning-and-Interaction-based Segmentation Approach Applied on CT Liver Volumes

    Directory of Open Access Journals (Sweden)

    M. Danciu

    2013-04-01

    Full Text Available Medical volume segmentation in various imaging modalities using real 3D approaches (in contrast to slice-by-slice segmentation represents an actual trend. The increase in the acquisition resolution leads to large amount of data, requiring solutions to reduce the dimensionality of the segmentation problem. In this context, the real-time interaction with the large medical data volume represents another milestone. This paper addresses the twofold problem of the 3D segmentation applied to large data sets and also describes an intuitive neuro-fuzzy trained interaction method. We present a new hybrid semi-supervised 3D segmentation, for liver volumes obtained from computer tomography scans. This is a challenging medical volume segmentation task, due to the acquisition and inter-patient variability of the liver parenchyma. The proposed solution combines a learning-based segmentation stage (employing 3D discrete cosine transform and a probabilistic support vector machine classifier with a post-processing stage (automatic and manual segmentation refinement. Optionally, an optimization of the segmentation can be achieved by level sets, using as initialization the segmentation provided by the learning-based solution. The supervised segmentation is applied on elementary cubes in which the CT volume is decomposed by tilling, thus ensuring a significant reduction of the data to be classified by the support vector machine into liver/not liver. On real volumes, the proposed approach provides good segmentation accuracy, with a significant reduction in the computational complexity.

  8. A four-step approach to evaluate mixtures for consistency with dose addition.

    Science.gov (United States)

    Hertzberg, Richard C; Pan, Yi; Li, Ruosha; Haber, Lynne T; Lyles, Robert H; Herr, David W; Moser, Virginia C; Simmons, Jane Ellen

    2013-11-16

    Mixture risk assessment is often hampered by the lack of dose-response information on the mixture being assessed, forcing reliance on component formulas such as dose addition. We present a four-step approach for evaluating chemical mixture data for consistency with dose addition for use in supporting a component based mixture risk assessment. Following the concepts in the U.S. EPA mixture risk guidance (U.S. EPA, 2000a,b), toxicological interaction for a defined mixture (all components known) is departure from a clearly articulated definition of component additivity. For the common approach of dose additivity, the EPA guidance identifies three desirable characteristics, foremost of which is that the component chemicals are toxicologically similar. The other two characteristics are empirical: the mixture components have toxic potencies that are fixed proportions of each other (throughout the dose range of interest), and the mixture dose term in the dose additive prediction formula, which we call the combined prediction model (CPM), can be represented by a linear combination of the component doses. A consequent property of the proportional toxic potencies is that the component chemicals must share a common dose-response model, where only the dose coefficients depend on the chemical components. A further consequence is that the mixture data must be described by the same mathematical function ("mixture model") as the components, but with a distinct coefficient for the total mixture dose. The mixture response is predicted from the component dose-response curves by using the dose additive CPM and the prediction is then compared with the observed mixture results. The four steps are to evaluate: (1) toxic proportionality by determining how well the CPM matches the single chemical models regarding mean and variance; (2) fit of the mixture model to the mixture data; (3) agreement between the mixture data and the CPM prediction; and (4) consistency between the CPM and the

  9. FLUID-BASED SIMULATION APPROACH FOR HIGH VOLUME CONVEYOR TRANSPORTATION SYSTEMS

    Institute of Scientific and Technical Information of China (English)

    Ying WANG; Chen ZHOU

    2004-01-01

    High volume conveyor systems in distribution centers have very large footprint and can handle large volumes and hold thousands of items. Traditional discrete-event cell-based approach to simulate such networks becomes computationally challenging. An alternative approach, in which the traffic is represented by segments of fluid flow of different density instead of individual packages, is presented in this paper to address this challenge. The proposed fluid-based simulation approach is developed using a Hybrid Petri Nets framework. The underlying model is a combination of an extension of a Batches Petri Nets (BPN) and a Stochastic Petri Nets (SPN). The extensions are in the inclusion of random elements and relaxation of certain structural constraints. Some adaptations are also made to fit the target system modeling. The approach is presented with an example.

  10. Trans-nipple removal of fibro-glandular tissue in gynaecomastia surgery without additional scars: An innovative approach

    Directory of Open Access Journals (Sweden)

    R K Mishra

    2014-01-01

    Full Text Available Context: The established techniques that have been used to treat gynaecomastia are said to have relatively less patient satisfaction rate as they leave some visible scars or mild elevation over the nipple areola complex, resulting in aesthetically unsatisfactory results. Even the slightest elevation or smallest scar over nipple areola complex leave patients extremely self conscious and in a dilemma of having a second intervention to get rid of that blemish. Aims: The aim of the study is to achieve - A flat chest without adding a scar and with no chances of re-occurrence of the condition. This article suggests an innovative approach to address the problem. Materials and Methods: The author presents trans-nipple incision approach for the delivery of fibro-glandular tissue component following liposuction for maximum patient satisfaction. This method consists of a unique small criss-cross incision right on the nipple itself for retrieving any volume of tough fibro-glandular tissues. Between the duration of January 2012 to October 2013, 28 male patients of different ages were operated with this technique. Results: The surgery resulted in well-shaped, symmetric chest contour without any visible elevation or additional scars on nipple areola complex. No complications were noticed in any of the patients. Conclusions: The presented technique is proved to have a high patient satisfaction rate and to be promising method to achieve good aesthetic results in gynaecomastia surgery.

  11. Capacity-Approaching Signal Constellations for the Additive Exponential Noise Channel

    CERN Document Server

    Goff, Stéphane Y Le

    2011-01-01

    We present a new family of signal constellations, called log constellations, that can be used to design near-capacity coded modulation schemes over additive exponential noise (AEN) channels. Log constellations are designed by geometrically approximating the input distribution that maximizes the AEN channel capacity. The mutual information achievable over AEN channels with both coded modulation (CM) and bit-interleaved coded modulation (BICM) approaches is evaluated for various signal sets. In the case of CM, the proposed log constellations outperform, sometimes by over half a decibel, the best existing signal sets available from the literature, and can display error performance within only 0.12 dB of the AEN channel capacity. In the context of BICM, log constellations do not offer significant performance advantages over the best existing constellations. As the potential performance degradation resulting from the use of BICM instead of CM is larger than 1 dB, BICM may however not be a suitable design approach ...

  12. Then and Now: Approaches to Understanding Children's Literature in Two Volumes

    Science.gov (United States)

    Bani-Khair, Baker M.; Khawaldeh, Imad M.

    2016-01-01

    This research paper investigates two main volumes taken from "Children's Literature Association Quarterly"; the earlier one is Vol. 11 published in 1986, and the other one, a more recent one, Vol. 32 published in 2007, as to understand the differences and similarities regarding the approaches used in the articles to understand Children's…

  13. An Adaptive Prediction-Based Approach to Lossless Compression of Floating-Point Volume Data.

    Science.gov (United States)

    Fout, N; Ma, Kwan-Liu

    2012-12-01

    In this work, we address the problem of lossless compression of scientific and medical floating-point volume data. We propose two prediction-based compression methods that share a common framework, which consists of a switched prediction scheme wherein the best predictor out of a preset group of linear predictors is selected. Such a scheme is able to adapt to different datasets as well as to varying statistics within the data. The first method, called APE (Adaptive Polynomial Encoder), uses a family of structured interpolating polynomials for prediction, while the second method, which we refer to as ACE (Adaptive Combined Encoder), combines predictors from previous work with the polynomial predictors to yield a more flexible, powerful encoder that is able to effectively decorrelate a wide range of data. In addition, in order to facilitate efficient visualization of compressed data, our scheme provides an option to partition floating-point values in such a way as to provide a progressive representation. We compare our two compressors to existing state-of-the-art lossless floating-point compressors for scientific data, with our data suite including both computer simulations and observational measurements. The results demonstrate that our polynomial predictor, APE, is comparable to previous approaches in terms of speed but achieves better compression rates on average. ACE, our combined predictor, while somewhat slower, is able to achieve the best compression rate on all datasets, with significantly better rates on most of the datasets.

  14. Comprehensive data base of high-level nuclear waste glasses: September 1987 status report: Volume 2, Additional appendices

    Energy Technology Data Exchange (ETDEWEB)

    Kindle, C.H.; Kreiter, M.R.

    1987-12-01

    The Materials Characterization Center (MCC) is assembling a comprehensive data base (CDB) of experimental data collected for high-level nuclear waste package components. The status of the CDB is summarized in Volume I of this report. Volume II contains appendices that present data from the data base and an evaluation of glass durability models applied to the data base.

  15. Precise segmentation of multiple organs in CT volumes using learning-based approach and information theory.

    Science.gov (United States)

    Lu, Chao; Zheng, Yefeng; Birkbeck, Neil; Zhang, Jingdan; Kohlberger, Timo; Tietjen, Christian; Boettger, Thomas; Duncan, James S; Zhou, S Kevin

    2012-01-01

    In this paper, we present a novel method by incorporating information theory into the learning-based approach for automatic and accurate pelvic organ segmentation (including the prostate, bladder and rectum). We target 3D CT volumes that are generated using different scanning protocols (e.g., contrast and non-contrast, with and without implant in the prostate, various resolution and position), and the volumes come from largely diverse sources (e.g., diseased in different organs). Three key ingredients are combined to solve this challenging segmentation problem. First, marginal space learning (MSL) is applied to efficiently and effectively localize the multiple organs in the largely diverse CT volumes. Second, learning techniques, steerable features, are applied for robust boundary detection. This enables handling of highly heterogeneous texture pattern. Third, a novel information theoretic scheme is incorporated into the boundary inference process. The incorporation of the Jensen-Shannon divergence further drives the mesh to the best fit of the image, thus improves the segmentation performance. The proposed approach is tested on a challenging dataset containing 188 volumes from diverse sources. Our approach not only produces excellent segmentation accuracy, but also runs about eighty times faster than previous state-of-the-art solutions. The proposed method can be applied to CT images to provide visual guidance to physicians during the computer-aided diagnosis, treatment planning and image-guided radiotherapy to treat cancers in pelvic region.

  16. A risk management approach to double-shell tank waste volume versus storage capacity

    Energy Technology Data Exchange (ETDEWEB)

    Coles, G.A. [Westinghouse Hanford Co., Richland, WA (United States); Thurkow, T.J.; Fritz, R.L.; Nuhlestein, L.O.; Allen, M.R.; Stuart, R.J. [ARES Corp. (United States)

    1996-01-01

    A risk-based assessment of the overall waste volume versus double-shell tank storage capacity was conducted to develop fallback positions for projections where the waste volume was at a high risk of exceeding capacity. This study was initiated to provide that assessment. A working simulation model was the primary deliverable of this study. The model validates the approach and demonstrates that simulation analysis can provide a method of tracking uncertainties in available data, assessing probabilities, and serves as a tool to be used by management to determine the consequences of various off-normal occurrences.

  17. Hot and Dense Hadron Gas (HG): A New Excluded-volume approach

    CERN Document Server

    Tiwari, S K

    2013-01-01

    We formulate a thermodynamically consistent equation of state (EOS), based on excluded-volume approach, for a hot, dense hadron gas (HG). We calculate various thermodynamical quantities of HG and various hadron ratios and compare our model results with the results of other excluded-volume models and experimental data. We also calculate various transport coefficients such as $\\eta/s$ etc. and compare them with other HG model results. Furthermore, we test the validity of our model in getting the rapidity spectra of various hadrons and the effect of flow on them is investigated by matching our predictions with the experimental data.

  18. Planning additional drilling campaign using two-space genetic algorithm: A game theoretical approach

    Science.gov (United States)

    Kumral, Mustafa; Ozer, Umit

    2013-03-01

    Grade and tonnage are the most important technical uncertainties in mining ventures because of the use of estimations/simulations, which are mostly generated from drill data. Open pit mines are planned and designed on the basis of the blocks representing the entire orebody. Each block has different estimation/simulation variance reflecting uncertainty to some extent. The estimation/simulation realizations are submitted to mine production scheduling process. However, the use of a block model with varying estimation/simulation variances will lead to serious risk in the scheduling. In the medium of multiple simulations, the dispersion variances of blocks can be thought to regard technical uncertainties. However, the dispersion variance cannot handle uncertainty associated with varying estimation/simulation variances of blocks. This paper proposes an approach that generates the configuration of the best additional drilling campaign to generate more homogenous estimation/simulation variances of blocks. In other words, the objective is to find the best drilling configuration in such a way as to minimize grade uncertainty under budget constraint. Uncertainty measure of the optimization process in this paper is interpolation variance, which considers data locations and grades. The problem is expressed as a minmax problem, which focuses on finding the best worst-case performance i.e., minimizing interpolation variance of the block generating maximum interpolation variance. Since the optimization model requires computing the interpolation variances of blocks being simulated/estimated in each iteration, the problem cannot be solved by standard optimization tools. This motivates to use two-space genetic algorithm (GA) approach to solve the problem. The technique has two spaces: feasible drill hole configuration with minimization of interpolation variance and drill hole simulations with maximization of interpolation variance. Two-space interacts to find a minmax solution

  19. Additive effects in high-voltage layered-oxide cells: A statistics of mixtures approach

    Science.gov (United States)

    Sahore, Ritu; Peebles, Cameron; Abraham, Daniel P.; Gilbert, James; Bloom, Ira

    2017-09-01

    Li1.03(Ni0.5Mn0.3Co0.2)0.97O2 (NMC)-based coin cells containing the electrolyte additives vinylene carbonate (VC) and tris(trimethylsilyl)phosphite (TMSPi) in the range of 0-2 wt% were cycled between 3.0 and 4.4 V. The changes in capacity at rates of C/10 and C/1 and resistance at 60% state of charge were found to follow linear-with-time kinetic rate laws. Further, the C/10 capacity and resistance data were amenable to modeling by a statistics of mixtures approach. Applying physical meaning to the terms in the empirical models indicated that the interactions between the electrolyte and additives were not simple. For example, there were strong, synergistic interactions between VC and TMSPi affecting C/10 capacity loss, as expected, but there were other, more subtle interactions between the electrolyte components. The interactions between these components controlled the C/10 capacity decline and resistance increase.

  20. Evaluating electrolyte additives for lithium-ion cells: A new Figure of Merit approach

    Science.gov (United States)

    Tornheim, Adam; Peebles, Cameron; Gilbert, James A.; Sahore, Ritu; Garcia, Juan C.; Bareño, Javier; Iddir, Hakim; Liao, Chen; Abraham, Daniel P.

    2017-10-01

    Electrolyte additives are known to improve the performance of lithium-ion cells. In this work we examine the performance of Li1.03Ni0.5Mn0.3Co0.3O2-graphite (NMC532/Gr) cells containing combinations of lithium bis(oxalate)borate (LiBOB), vinylene carbonate (VC), trivinylcyclotriboroxane (tVCBO), prop-1-ene-1,3-sultone (PES), phenyl boronic acid ethylene glycol ester (PBE), tris(trimethylsilyl) phosphite (TMSPi), triethyl phosphite (TEPi), and lithium difluoro(oxalate)borate (LiDFOB) added to our baseline (1.2 M LiPF6 in EC:EMC, 3:7 w/w) electrolyte. In order to rank performance of the various electrolytes, we developed two separate figures of merit (FOM), which are based on the energy retention and power retention of the cells. Using these two metrics in conjunction, we show that only one of the fifteen electrolyte formulations tested significantly outperforms the baseline electrolyte: this electrolyte contains the 0.25 wt% tVCBO + 1 wt% TMSPi additive mix. Little correlation was observed between the FOMs for energy retention and power retention, which indicates that the mechanisms that govern these performance parameters are likely independent of each other. Our FOM approach has general applicability and can be used to develop electrolyte and electrode formulations that prolong the life of lithium-ion batteries.

  1. Detection of triazole deicing additives in soil samples from airports with low, mid, and large volume aircraft deicing activities.

    Science.gov (United States)

    McNeill, K S; Cancilla, D A

    2009-03-01

    Soil samples from three USA airports representing low, mid, and large volume users of aircraft deicing fluids (ADAFs) were analyzed by LC/MS/MS for the presence of triazoles, a class of corrosion inhibitors historically used in ADAFs. Triazoles, specifically the 4-methyl-1H-benzotriazole and the 5-methyl-1H-benzotriazole, were detected in a majority of samples and ranged from 2.35 to 424.19 microg/kg. Previous studies have focused primarily on ground and surface water impacts of larger volume ADAF users. The detection of triazoles in soils at low volume ADAF use airports suggests that deicing activities may have a broader environmental impact than previously considered.

  2. 76 FR 21418 - Fiscal Year 2011 Allocation of Additional Tariff-Rate Quota Volume for Raw Cane Sugar and...

    Science.gov (United States)

    2011-04-15

    ... Sugar and Reallocation of Unused Fiscal Year 2011 Tariff-Rate Quota Volume for Raw Cane Sugar AGENCY... Fiscal Year (FY) 2011 in-quota quantity of the tariff-rate quota (TRQ) for imported raw cane sugar and of... raw cane sugar. DATES: Effective Date: April 15, 2011. ADDRESSES: Inquiries may be mailed or delivered...

  3. 77 FR 25012 - Fiscal Year 2012 Allocation of Additional Tariff-Rate Quota Volume for Raw Cane Sugar and...

    Science.gov (United States)

    2012-04-26

    ... Sugar and Reallocation of Unused Fiscal Year 2012 Tariff-Rate Quota Volume for Raw Cane Sugar AGENCY... Fiscal Year (FY) 2012 in-quota quantity of the tariff-rate quota (TRQ) for imported raw cane sugar and of... raw cane sugar. DATES: Effective Date: April 26, 2012. ADDRESSES: Inquiries may be mailed or delivered...

  4. Excluded volume effects caused by high concentration addition of acid generators in chemically amplified resists used for extreme ultraviolet lithography

    Science.gov (United States)

    Kozawa, Takahiro; Watanabe, Kyoko; Matsuoka, Kyoko; Yamamoto, Hiroki; Komuro, Yoshitaka; Kawana, Daisuke; Yamazaki, Akiyoshi

    2017-08-01

    The resolution of lithography used for the high-volume production of semiconductor devices has been improved to meet the market demands for highly integrated circuits. With the reduction in feature size, the molecular size becomes non-negligible in the resist material design. In this study, the excluded volume effects caused by adding high-concentration acid generators were investigated for triphenylsulfonium nonaflate. The resist film density was measured by X-ray diffractometry. The dependences of absorption coefficient and protected unit concentration on acid generator weight ratio were calculated from the measured film density. Using these values, the effects on the decomposition yield of acid generators, the protected unit fluctuation, and the line edge roughness (LER) were evaluated by simulation on the basis of sensitization and reaction mechanisms of chemically amplified extreme ultraviolet resists. The positive effects of the increase in acid generator weight ratio on LER were predominant below the acid generator weight ratio of 0.3, while the negative effects became equivalent to the positive effects above the acid generator weight ratio of 0.3 owing to the excluded volume effects.

  5. Patterns of failure after the reduced volume approach for elective nodal irradiation in nasopharyngeal carcinoma

    Energy Technology Data Exchange (ETDEWEB)

    Seol, Ki Ho; Lee, Jeong Eun [Dept. of Radiation Oncology, Kyungpook National University School of Medicine, Daegu (Korea, Republic of)

    2016-03-15

    To evaluate the patterns of nodal failure after radiotherapy (RT) with the reduced volume approach for elective neck nodal irradiation (ENI) in nasopharyngeal carcinoma (NPC). Fifty-six NPC patients who underwent definitive chemoradiotherapy with the reduced volume approach for ENI were reviewed. The ENI included retropharyngeal and level II lymph nodes, and only encompassed the echelon inferior to the involved level to eliminate the entire neck irradiation. Patients received either moderate hypofractionated intensity-modulated RT for a total of 72.6 Gy (49.5 Gy to elective nodal areas) or a conventional fractionated three-dimensional conformal RT for a total of 68.4-72 Gy (39.6-45 Gy to elective nodal areas). Patterns of failure, locoregional control, and survival were analyzed. The median follow-up was 38 months (range, 3 to 80 months). The out-of-field nodal failure when omitting ENI was none. Three patients developed neck recurrences (one in-field recurrence in the 72.6 Gy irradiated nodal area and two in the elective irradiated region of 39.6 Gy). Overall disease failure at any site developed in 11 patients (19.6%). Among these, there were six local failures (10.7%), three regional failures (5.4%), and five distant metastases (8.9%). The 3-year locoregional control rate was 87.1%, and the distant failure-free rate was 90.4%; disease-free survival and overall survival at 3 years was 80% and 86.8%, respectively. No patient developed nodal failure in the omitted ENI site. Our investigation has demonstrated that the reduced volume approach for ENI appears to be a safe treatment approach in NPC.

  6. An Electric Field Volume Integral Equation Approach to Simulate Surface Plasmon Polaritons

    Directory of Open Access Journals (Sweden)

    R. Remis

    2013-02-01

    Full Text Available In this paper we present an electric field volume integral equation approach to simulate surface plasmon propagation along metal/dielectric interfaces. Metallic objects embedded in homogeneous dielectric media are considered. Starting point is a so-called weak-form of the electric field integral equation. This form is discretized on a uniform tensor-product grid resulting in a system matrix whose action on a vector can be computed via the fast Fourier transform. The GMRES iterative solver is used to solve the discretized set of equations and numerical examples, illustrating surface plasmon propagation, are presented. The convergence rate of GMRES is discussed in terms of the spectrum of the system matrix and through numerical experiments we show how the eigenvalues of the discretized volume scattering operator are related to plasmon propagation and the medium parameters of a metallic object.

  7. Morphological study of surgical approach by superior temporal sulcus-temporal horn of lateral ventricle approach using volume rendering.

    Science.gov (United States)

    Sun, Wei; Jia, Linpei; Dong, Yidian; Zhao, Hang; Liu, Haoyuan; Yang, Kerong; Li, Youqiong

    2014-03-01

    In this research, we acquired the length of the superior temporal sulcus, the shortest distance from the superior temporal sulcus to the temporal horn of the lateral ventricle, and the approach angle between the median sagittal plane and the shortest segment from the superior temporal sulcus to the temporal horn of the lateral ventricle measuring 98 specimens by magnetic resonance imaging volume rendering. At the same time, we preliminarily oriented the point of the superior temporal sulcus, which is closest to the temporal horn of the lateral ventricle, aimed at finding out the best entrance point of surgical approach through the superior temporal sulcus to the temporal horn of the lateral ventricle and reducing the damage to optic radiation as well as other nerve fibers during the operation. The results indicate that the point at the front side 3/5 of the superior temporal sulcus may be the ideal surgical approach entrance point, and there is no difference between 2 cerebral hemispheres (P < 0.05).

  8. Structured assessment approach: Version I. Applied demonstration of output results. Volume 3

    Energy Technology Data Exchange (ETDEWEB)

    Parziale, A.A.; Sacks, 1.J.

    1979-10-01

    A methodology, the Structured Assessment Approach, has been developed for the assessment of the effectiveness of material control and accounting (MC and A) safeguards systems at nuclear fuel cycle facilities. This methodology has been refined into a computational tool, the SAA Version 1 computational package, that was used first to analyze a hypothetical fuel cycle facility (HFCF) and used more recently to assess operational nuclear plants. The Version 1 analysis package is designed to analyze safeguards systems that prevent the diversion of special nuclear material (SNM) from nuclear fuel cycle facilities and to provide assurance that diversion has not occurred. This report is the third volume, Applied Demonstration of Output Results, of a four-volume document. It presents the outputs for each of the four levels of the SAA Version 1 computational package. Two types of outputs are discussed: detailed output findings and summary output tables. The summary output tables are used to aggregate the detailed output findings in a condensed form for NRC analyst consumption. Specific output results are presented for an HFCF, which is described in Volume II.

  9. Combining small-volume metabolomic and transcriptomic approaches for assessing brain chemistry.

    Science.gov (United States)

    Knolhoff, Ann M; Nautiyal, Katherine M; Nemes, Peter; Kalachikov, Sergey; Morozova, Irina; Silver, Rae; Sweedler, Jonathan V

    2013-03-19

    The integration of disparate data types provides a more complete picture of complex biological systems. Here we combine small-volume metabolomic and transcriptomic platforms to determine subtle chemical changes and to link metabolites and genes to biochemical pathways. Capillary electrophoresis-mass spectrometry (CE-MS) and whole-genome gene expression arrays, aided by integrative pathway analysis, were utilized to survey metabolomic/transcriptomic hippocampal neurochemistry. We measured changes in individual hippocampi from the mast cell mutant mouse strain, C57BL/6 Kit(W-sh/W-sh). These mice have a naturally occurring mutation in the white spotting locus that causes reduced c-Kit receptor expression and an inability of mast cells to differentiate from their hematopoietic progenitors. Compared with their littermates, the mast cell-deficient mice have profound deficits in spatial learning, memory, and neurogenesis. A total of 18 distinct metabolites were identified in the hippocampus that discriminated between the C57BL/6 Kit(W-sh/W-sh) and control mice. The combined analysis of metabolite and gene expression changes revealed a number of altered pathways. Importantly, results from both platforms indicated that multiple pathways are impacted, including amino acid metabolism, increasing the confidence in each approach. Because the CE-MS and expression profiling are both amenable to small-volume analysis, this integrated analysis is applicable to a range of volume-limited biological systems.

  10. Automated mass detection in contrast-enhanced CT colonography: an approach based on contrast and volume

    Energy Technology Data Exchange (ETDEWEB)

    Luboldt, W. [University Hospital Essen, Clinic and Policlinic of Angiology, Essen (Germany); Multiorgan Screening Foundation (Germany); Tryon, C. [Philips Medical Systems, Best (Netherlands); Kroll, M.; Vogl, T.J. [University Hospital Frankfurt, Department of Radiology, Frankfurt (Germany); Toussaint, T.L. [Multiorgan Screening Foundation (Germany); Holzer, K. [University Hospital Frankfurt, Department of Visceral and Vascular Surgery, Frankfurt (Germany); Hoepffner, N. [University Hospital Frankfurt, Department of Gastroenterology, Frankfurt (Germany)

    2005-02-01

    The purpose of this feasibility study was to design and test an algorithm for automating mass detection in contrast-enhanced CT colonography (CTC). Five patients with known colorectal masses underwent a pre-surgical contrast-enhanced (120 ml volume 1.6 g iodine/s injection rate, 60 s scan delay) CTC in high spatial resolution (16-slice CT: collimation: 16 x 0.75 mm, tablefeed: 24 mm/0.5 s, reconstruction increment: 0.5 mm). A CT-density- and volume-based algorithm searched for masses in the colonic wall, which was extracted before by segmenting and dilating the colonic air lumen and subtracting the inner air. A radiologist analyzed the detections and causes of false positives. All masses were detected, and false positives were easy to identify. Combining CT density with volume as a cut-off is a promising approach for automating mass detection that should be further refined and also tested in contrast-enhanced MR colonography. (orig.)

  11. A white matter lesion-filling approach to improve brain tissue volume measurements

    Directory of Open Access Journals (Sweden)

    Sergi Valverde

    2014-01-01

    Full Text Available Multiple sclerosis white matter (WM lesions can affect brain tissue volume measurements of voxel-wise segmentation methods if these lesions are included in the segmentation process. Several authors have presented different techniques to improve brain tissue volume estimations by filling WM lesions before segmentation with intensities similar to those of WM. Here, we propose a new method to refill WM lesions, where contrary to similar approaches, lesion voxel intensities are replaced by random values of a normal distribution generated from the mean WM signal intensity of each two-dimensional slice. We test the performance of our method by estimating the deviation in tissue volume between a set of 30 T1-w 1.5 T and 30 T1-w 3 T images of healthy subjects and the same images where: WM lesions have been previously registered and afterwards replaced their voxel intensities to those between gray matter (GM and WM tissue. Tissue volume is computed independently using FAST and SPM8. When compared with the state-of-the-art methods, on 1.5 T data our method yields the lowest deviation in WM between original and filled images, independently of the segmentation method used. It also performs the lowest differences in GM when FAST is used and equals to the best method when SPM8 is employed. On 3 T data, our method also outperforms the state-of-the-art methods when FAST is used while performs similar to the best method when SPM8 is used. The proposed technique is currently available to researchers as a stand-alone program and as an SPM extension.

  12. Showing their true colors: a practical approach to volume rendering from serial sections

    Directory of Open Access Journals (Sweden)

    Metscher Brian D

    2010-04-01

    Full Text Available Abstract Background In comparison to more modern imaging methods, conventional light microscopy still offers a range of substantial advantages with regard to contrast options, accessible specimen size, and resolution. Currently, tomographic image data in particular is most commonly visualized in three dimensions using volume rendering. To date, this method has only very rarely been applied to image stacks taken from serial sections, whereas surface rendering is still the most prevalent method for presenting such data sets three-dimensionally. The aim of this study was to develop standard protocols for volume rendering of image stacks of serial sections, while retaining the benefits of light microscopy such as resolution and color information. Results Here we provide a set of protocols for acquiring high-resolution 3D images of diverse microscopic samples through volume rendering based on serial light microscopical sections using the 3D reconstruction software Amira (Visage Imaging Inc.. We overcome several technical obstacles and show that these renderings are comparable in quality and resolution to 3D visualizations using other methods. This practical approach for visualizing 3D micro-morphology in full color takes advantage of both the sub-micron resolution of light microscopy and the specificity of histological stains, by combining conventional histological sectioning techniques, digital image acquisition, three-dimensional image filtering, and 3D image manipulation and visualization technologies. Conclusions We show that this method can yield "true"-colored high-resolution 3D views of tissues as well as cellular and sub-cellular structures and thus represents a powerful tool for morphological, developmental, and comparative investigations. We conclude that the presented approach fills an important gap in the field of micro-anatomical 3D imaging and visualization methods by combining histological resolution and differentiation of details with

  13. Showing their true colors: a practical approach to volume rendering from serial sections.

    Science.gov (United States)

    Handschuh, Stephan; Schwaha, Thomas; Metscher, Brian D

    2010-04-21

    In comparison to more modern imaging methods, conventional light microscopy still offers a range of substantial advantages with regard to contrast options, accessible specimen size, and resolution. Currently, tomographic image data in particular is most commonly visualized in three dimensions using volume rendering. To date, this method has only very rarely been applied to image stacks taken from serial sections, whereas surface rendering is still the most prevalent method for presenting such data sets three-dimensionally. The aim of this study was to develop standard protocols for volume rendering of image stacks of serial sections, while retaining the benefits of light microscopy such as resolution and color information. Here we provide a set of protocols for acquiring high-resolution 3D images of diverse microscopic samples through volume rendering based on serial light microscopical sections using the 3D reconstruction software Amira (Visage Imaging Inc.). We overcome several technical obstacles and show that these renderings are comparable in quality and resolution to 3D visualizations using other methods. This practical approach for visualizing 3D micro-morphology in full color takes advantage of both the sub-micron resolution of light microscopy and the specificity of histological stains, by combining conventional histological sectioning techniques, digital image acquisition, three-dimensional image filtering, and 3D image manipulation and visualization technologies. We show that this method can yield "true"-colored high-resolution 3D views of tissues as well as cellular and sub-cellular structures and thus represents a powerful tool for morphological, developmental, and comparative investigations. We conclude that the presented approach fills an important gap in the field of micro-anatomical 3D imaging and visualization methods by combining histological resolution and differentiation of details with 3D rendering of whole tissue samples. We demonstrate the

  14. Tank mixture additives approach to improve efficiency of bentazon against broadleaf weeds in peas.

    Science.gov (United States)

    Balah, Mohamed A; Hanafi, Ahmad; Ghani, Sherif B Abdel

    2012-01-01

    Efficiency of different tank-mixed additives with bentazon at half rate was investigated on (Malva parviflora) and other broad leaf weeds compared with bentazon at the full recommended rate without additives in peas in open field. All the tested additives enhanced the efficiency of bentazon at the half rate. Nonyl phenol and toximol S proved to be the most effective additives in comparison with the full rate treatment. The tested treatments did not show any significant effect on chlorophyll content and soil microorganisms. Bentazon residues were determined in certain treatments to investigate the effect of the tested additives on bentazon deposition. Samples were extracted using QuEChERS method and residues were determined using LC-MS/MS. Residues after 24 hours in the half rate treatment reached 4 times lower than the Maximum Residues Limit (MRL) (0.11 mg kg(-1)), compared to the full rate treatment (0.51 mg kg(-1)), that was slightly above the MRL.

  15. Quantitative Analysis of Polymer Additives with MALDI-TOF MS Using an Internal Standard Approach

    Science.gov (United States)

    Schwarzinger, Clemens; Gabriel, Stefan; Beißmann, Susanne; Buchberger, Wolfgang

    2012-06-01

    MALDI-TOF MS is used for the qualitative analysis of seven different polymer additives directly from the polymer without tedious sample pretreatment. Additionally, by using a solid sample preparation technique, which avoids the concentration gradient problems known to occur with dried droplets and by adding tetraphenylporphyrine as an internal standard to the matrix, it is possible to perform quantitative analysis of additives directly from the polymer sample. Calibration curves for Tinuvin 770, Tinuvin 622, Irganox 1024, Irganox 1010, Irgafos 168, and Chimassorb 944 are presented, showing coefficients of determination between 0.911 and 0.990.

  16. A moving control volume approach to computing hydrodynamic forces and torques on immersed bodies

    Science.gov (United States)

    Nangia, Nishant; Johansen, Hans; Patankar, Neelesh A.; Bhalla, Amneet Pal Singh

    2017-10-01

    We present a moving control volume (CV) approach to computing hydrodynamic forces and torques on complex geometries. The method requires surface and volumetric integrals over a simple and regular Cartesian box that moves with an arbitrary velocity to enclose the body at all times. The moving box is aligned with Cartesian grid faces, which makes the integral evaluation straightforward in an immersed boundary (IB) framework. Discontinuous and noisy derivatives of velocity and pressure at the fluid-structure interface are avoided and far-field (smooth) velocity and pressure information is used. We re-visit the approach to compute hydrodynamic forces and torques through force/torque balance equations in a Lagrangian frame that some of us took in a prior work (Bhalla et al., 2013 [13]). We prove the equivalence of the two approaches for IB methods, thanks to the use of Peskin's delta functions. Both approaches are able to suppress spurious force oscillations and are in excellent agreement, as expected theoretically. Test cases ranging from Stokes to high Reynolds number regimes are considered. We discuss regridding issues for the moving CV method in an adaptive mesh refinement (AMR) context. The proposed moving CV method is not limited to a specific IB method and can also be used, for example, with embedded boundary methods.

  17. A Micro-Developmental Approach to Studying Young Children's Problem Solving Behavior in Addition

    Science.gov (United States)

    Voutsina, Chronoula

    2012-01-01

    This paper presents a study that investigated the process of change in 5-6-year-old children's successful problem-solving approaches when tackling a multiple-step task in elementary arithmetic. Micro-developmental changes in children's successful problem-solving behavior were analyzed using Karmiloff-Smith's model of representational redescription…

  18. A novel approach for phosphorus recovery and no wasted sludge in enhanced biological phosphorus removal process with external COD addition.

    Science.gov (United States)

    Xia, Cheng-Wang; Ma, Yun-Jie; Zhang, Fang; Lu, Yong-Ze; Zeng, Raymond J

    2014-01-01

    In enhanced biological phosphorus removal (EBPR) process, phosphorus (P) in wastewater is removed via wasted sludge without actual recovery. A novel approach to realize phosphorus recovery with special external chemical oxygen demand (COD) addition in EBPR process was proposed. During the new operating approach period, it was found that (1) no phosphorus was detected in the effluent; (2) with an external addition of 10 % of influent COD amount, 79 % phosphorus in the wastewater influent was recovered; (3) without wasted sludge, the MLVSS concentration in the system increased from 2,010 to 3,400 mg/L and kept stable after day 11 during 24-day operating period. This demonstrates that the novel approach is feasible to realize phosphorus recovery with no wasted sludge discharge in EBPR process. Furthermore, this approach decouples P removal and sludge age, which may enhance the application of membrane bioreactor for P removal.

  19. Planning and design of additional East Mesa Geothermal Test Facilities. Phase 1B. Volume II. Procurement package

    Energy Technology Data Exchange (ETDEWEB)

    Pearson, R.O.

    1976-10-15

    Procurement packages of technical specifications and construction drawings for eleven test facility additions to the ERDA East Mesa Geothermal Component Test Facility are presented. Each of the specifications includes all of the technical requirements needed for procurement and construction starting with Division 2. The information is presented under the following subject headings: injection pump system: 52-2 injection pipeline; control and instrumentation spools; calibration test bench; test pad modifications; test pad piping headers; production and injection wells; well 5-2 modifications; well 8-1 down-hole pump; well 6-1 down-hole pump; and well 8-1 booster pump. (JGB)

  20. APPROACHES TO GEOMETRIC DATA ANALYSIS ON BIG AREA ADDITIVELY MANUFACTURED (BAAM) PARTS

    Energy Technology Data Exchange (ETDEWEB)

    Dreifus, Gregory D [ORNL; Ally, Nadya R [ORNL; Post, Brian K [ORNL; Jin, Yuan [ORNL

    2016-01-01

    The promise of additive manufacturing is that a user can design and print complex geometries that are very difficult, if not impossible, to machine. The capabilities of 3D printing are restricted by a number of factors, including properties of the build material, time constraints, and geometric design restrictions. In this paper, a thorough accounting and study of the geometric restrictions that exist in the current iteration of additive manufacturing (AM) fused deposition modeling (FDM) technologies are discussed. Offline and online methodologies for collecting data sets for qualitative analysis of large scale AM, in particular Oak Ridge National Laboratory s (ORNL) big area additive manufacturing (BAAM) system, are summarized. In doing so, a survey of tools for designers and software developers is provided. In particular, strategies in which geometric data can be used as training sets for smarter AM technologies in the future are explained as well.

  1. Additive manufacturing: a new approach to realize complex and unconventional optical components

    Science.gov (United States)

    Heinrich, Andreas; Rank, Manuel; Suresh Nair, Sangeetha; Bauckhage, Y.; Maillard, Phillipe

    2017-02-01

    In recent years, additive manufacturing methods became more and more prominent. Thereby, these techniques are mainly used in order to realize mechanical components. But the additive manufacturing technology offers a high potential in the field of optics as well. Owing to new design possibilities, completely new solutions are possible. We report on the realization of complex freeform optics using standard 3D printers. We briefly point out the characteristics of 3D printing and its influence on the optical properties. Additionally we address the needed rework of 3D printed optical components. Therefore we apply two different methods - a robot-based fluid jet polishing and a coating method. The advantage of a 3D printed optic lies in its shape complexity. Thus different complex shaped optical elements are discussed. They are used for either metrology tasks or illumination tasks.

  2. A pyramid-based approach to visual exploration of a large volume of vehicle trajectory data

    Institute of Scientific and Technical Information of China (English)

    Jing SUN; Xiang LI

    2012-01-01

    Advances in positioning and wireless communicating technologies make it possible to collect large volumes of trajectory data of moving vehicles in a fast and convenient fashion.These data can be applied to traffic studies.Behind this application,a methodological issue that still requires particular attention is the way these data should be spatially visualized.Trajectory data physically consists of a large number of positioning points.With the dramatic increase of data volume,it becomes a challenge to display and explore these data.Existing commercial software often employs vector-based indexing structures to facilitate the display of a large volume of points,but their performance downgrades quickly when the number of points is very large,for example,tens of millions.In this paper,a pyramid-based approach is proposed.A pyramid method initially is invented to facilitate the display of raster images through the tradeoff between storage space and display time.A pyramid is a set of images at different levels with different resolutions.In this paper,we convert vector-based point data into raster data,and build a gridbased indexing structure in a 2D plane.Then,an image pyramid is built.Moreover,at the same level of a pyramid,image is segmented into mosaics with respect to the requirements of data storage and management.Algorithms or procedures on grid-based indexing structure,image pyramid,image segmentation,and visualization operations are given in this paper.A case study with taxi trajectory data in Shanghai is conducted.Results demonstrate that the proposed method outperforms the existing commercial software.

  3. Additive Representations of Preferences, A New Foundation of Decision Analysis; The Algebraic Approach

    NARCIS (Netherlands)

    P.P. Wakker (Peter)

    1991-01-01

    textabstractIn Wakker (1989, "Additive Representations of Preferences, A New Foundation of Decision Analysis"), a new foundation of decision analysis was given. The main tool was a way to derive comparisons of "tradeoffs" from ordinal preferences, with comparisons of tradeoffs revealing orderings of

  4. Additive reprensentations of preferences, a new foundation of decision analysis: the algebraic approach

    NARCIS (Netherlands)

    Wakker, P.P.; Doignon, J.P.; Falmagne, J.C.

    1991-01-01

    In Wakker (1989, "Additive Representations of Preferences, A New Foundation of Decision Analysis"), a new foundation of decision analysis was given. The main tool was a way to derive comparisons of "tradeoffs" from ordinal preferences, with comparisons of tradeoffs revealing orderings of utility dif

  5. A new approach of binary addition and subtraction by non-linear material based switching technique

    Indian Academy of Sciences (India)

    Archan Kumar Das; Partha Partima Das; Sourangshu Mukhopadhyay

    2005-02-01

    Here, we refer a new proposal of binary addition as well as subtraction in all-optical domain by exploitation of proper non-linear material-based switching technique. In this communication, the authors extend this technique for both adder and subtractor accommodating the spatial input encoding system.

  6. A fixed point approach to the stability of an additive cubic functional equation in paranormed spaces

    Directory of Open Access Journals (Sweden)

    K. Ravi

    2014-03-01

    Full Text Available In this paper, using fixed point method we prove the generalized Hyers Ulam Rassias stability of the additive cubic functional equationf(x-ky=k2[f(x+y+ f(x-y]+2(1- k2f(x for fixed integers k, with k≠0,±1 in paranormed spaces.

  7. Curricular Approaches to Connecting Subtraction to Addition and Fostering Fluency with Basic Differences in Grade 1

    Science.gov (United States)

    Baroody, Arthur J.

    2016-01-01

    Six widely used US Grade 1 curricula do not adequately address the following three developmental prerequisites identified by a proposed learning trajectory for the meaningful learning of the subtraction-as-addition strategy (e.g., for 13-8 think "what + 8 = 13?"): (a) reverse operations (adding 8 is undone by subtracting 8); (b) common…

  8. Evaluating Drugs and Food Additives for Public Use: A Case Studies Approach.

    Science.gov (United States)

    Merritt, Sheridan V.

    1980-01-01

    Described is a case study used in an introductory college biology course that provides a basis for generating debate on an issue concerning the regulation of controversial food additives and prescription drugs. The case study contained within this article deals with drug screening, specifically with information related to thalidomide. (CS)

  9. NUMERICAL SIMULATION OF ELECTRICAL IMPEDANCE TOMOGRAPHY PROBLEM AND STUDY OF APPROACH BASED ON FINITE VOLUME METHOD

    Directory of Open Access Journals (Sweden)

    Ye. S. Sherina

    2014-01-01

    Full Text Available This research has been aimed to carry out a study of peculiarities that arise in a numerical simulation of the electrical impedance tomography (EIT problem. Static EIT image reconstruction is sensitive to a measurement noise and approximation error. A special consideration has been given to reducing of the approximation error, which originates from numerical implementation drawbacks. This paper presents in detail two numerical approaches for solving EIT forward problem. The finite volume method (FVM on unstructured triangular mesh is introduced. In order to compare this approach, the finite element (FEM based forward solver was implemented, which has gained the most popularity among researchers. The calculated potential distribution with the assumed initial conductivity distribution has been compared to the analytical solution of a test Neumann boundary problem and to the results of problem simulation by means of ANSYS FLUENT commercial software. Two approaches to linearized EIT image reconstruction are discussed. Reconstruction of the conductivity distribution is an ill-posed problem, typically requiring a large amount of computation and resolved by minimization techniques. The objective function to be minimized is constructed of measured voltage and calculated boundary voltage on the electrodes. A classical modified Newton type iterative method and the stochastic differential evolution method are employed. A software package has been developed for the problem under investigation. Numerical tests were conducted on simulated data. The obtained results could be helpful to researches tackling the hardware and software issues for medical applications of EIT.

  10. VOXEL-BASED APPROACH FOR ESTIMATING URBAN TREE VOLUME FROM TERRESTRIAL LASER SCANNING DATA

    Directory of Open Access Journals (Sweden)

    C. Vonderach

    2012-07-01

    Full Text Available The importance of single trees and the determination of related parameters has been recognized in recent years, e.g. for forest inventories or management. For urban areas an increasing interest in the data acquisition of trees can be observed concerning aspects like urban climate, CO2 balance, and environmental protection. Urban trees differ significantly from natural systems with regard to the site conditions (e.g. technogenic soils, contaminants, lower groundwater level, regular disturbance, climate (increased temperature, reduced humidity and species composition and arrangement (habitus and health status and therefore allometric relations cannot be transferred from natural sites to urban areas. To overcome this problem an extended approach was developed for a fast and non-destructive extraction of branch volume, DBH (diameter at breast height and height of single trees from point clouds of terrestrial laser scanning (TLS. For data acquisition, the trees were scanned with highest scan resolution from several (up to five positions located around the tree. The resulting point clouds (20 to 60 million points are analysed with an algorithm based on voxel (volume elements structure, leading to an appropriate data reduction. In a first step, two kinds of noise reduction are carried out: the elimination of isolated voxels as well as voxels with marginal point density. To obtain correct volume estimates, the voxels inside the stem and branches (interior voxels where voxels contain no laser points must be regarded. For this filling process, an easy and robust approach was developed based on a layer-wise (horizontal layers of the voxel structure intersection of four orthogonal viewing directions. However, this procedure also generates several erroneous "phantom" voxels, which have to be eliminated. For this purpose the previous approach was extended by a special region growing algorithm. In a final step the volume is determined layer-wise based on the

  11. Quasi-chemical approach for adsorption of mixtures with non-additive lateral interactions

    Science.gov (United States)

    Pinto, O. A.; Pasinetti, P. M.; Ramirez-Pastor, A. J.

    2017-01-01

    The statistical thermodynamics of binary mixtures with non-additive lateral interactions was developed on a generalization in the spirit of the lattice-gas model and the classical quasi-chemical approximation (QCA). The traditional assumption of a strictly pairwise additive nearest-neighbors interaction is replaced by a more general one, namely that the bond linking a certain atom with any of its neighbors depends considerably on how many of them are actually present (or absent) on the sites in the first coordination shell of the atom. The total and partial adsorption isotherms are given for both attractive and repulsive lateral interactions between the adsorbed species. Interesting behaviors are observed and discussed in terms of the low-temperature phases formed in the system. Comparisons with Monte Carlo simulations are performed in order to test the validity of the theoretical model.

  12. An Approach to the Classification of Potential Reserve Additions of Giant Oil Fields of the World

    Science.gov (United States)

    Klett, T.R.; Tennyson, M.E.

    2008-01-01

    This report contains slides and notes for slides for a presentation given to the Committee on Sustainable Energy and the Ad Hoc Group of Experts on Harmonization of Fossil Energy and Mineral Resources Terminology on 17 October 2007 in Geneva, Switzerland. The presentation describes the U.S. Geological Survey study to characterize and quantify petroleum-reserve additions, and the application of this study to help classify the quantities.

  13. Asymmetry Effects in Chinese Stock Markets Volatility: A Generalized Additive Nonparametric Approach

    OpenAIRE

    Hou, Ai Jun

    2007-01-01

    The unique characteristics of the Chinese stock markets make it difficult to assume a particular distribution for innovations in returns and the specification form of the volatility process when modeling return volatility with the parametric GARCH family models. This paper therefore applies a generalized additive nonparametric smoothing technique to examine the volatility of the Chinese stock markets. The empirical results indicate that an asymmetric effect of negative news exists in the Chin...

  14. A Greener, Efficient Approach to Michael Addition of Barbituric Acid to Nitroalkene in Aqueous Diethylamine Medium

    Directory of Open Access Journals (Sweden)

    Hany J. Al-Najjar

    2014-01-01

    Full Text Available An efficient method for the synthesis of a variety of pyrimidine derivatives 3a–t by reaction of barbituric acids 1a,b as Michael donor with nitroalkenes 2a–k as Michael acceptor using an aqueous medium and diethylamine is described. This 1,4-addition strategy offers several advantages, such as using an economic and environmentally benign reaction media, high yields, versatility, and shorter reaction times. The synthesized compounds were identified by 1H-NMR, 13C-NMR, CHN, IR, and MS. The structure of compound 3a was further confirmed by single crystal X-ray structure determination.

  15. Variational level set approach for automatic correction of multiplicative and additive intensity inhomogeneities in brain MR Images.

    Science.gov (United States)

    Verma, Nishant; Cowperthwaite, Matthew C; Markey, Mia K

    2012-01-01

    Retrospective correction of intensity inhomogeneities in magnetic resonance images of the brain is an essential pre-processing step before any sophisticated image analysis task can be performed. A popular choice when defining the degradation model in MR images is to use multiplicative intensity inhomogeneities that slowly varying across the image domain; this approach has been extensively used for bias field estimation. However, such a multiplicative model is often insufficient given that some of the most dominant physical causes of intensity inhomogeneities in MRI (such as nonuniform excitation strength) have a non-linear relationship with the receptor signal intensity. In this study, we consider a linear image degradation model with multiplicative and additive intensity inhomogeneity components. We propose a variational level sets approach that combines estimation of intensity inhomogeneity components during the image segmentation process. The evaluation of proposed approach on real MR image datasets demonstrate accurate estimation of multiplicative and additive intensity inhomogeneities improving brain tissue segmentation.

  16. Additional results for 'Sequential design approaches for bioequivalence studies with crossover designs'.

    Science.gov (United States)

    Montague, Timothy H; Potvin, Diane; Diliberti, Charles E; Hauck, Walter W; Parr, Alan F; Schuirmann, Donald J

    2012-01-01

    In 2008, this group published a paper on approaches for two-stage crossover bioequivalence (BE) studies that allowed for the reestimation of the second-stage sample size based on the variance estimated from the first-stage results. The sequential methods considered used an assumed GMR of 0.95 as part of the method for determining power and sample size. This note adds results for an assumed GMR = 0.90. Two of the methods recommended for GMR = 0.95 in the earlier paper have some unacceptable increases in Type I error rate when the GMR is changed to 0.90. If a sponsor wants to assume 0.90 for the GMR, Method D is recommended. Copyright © 2011 John Wiley & Sons, Ltd.

  17. Effect of additional warning sounds on pedestrians' detection of electric vehicles: An ecological approach.

    Science.gov (United States)

    Fleury, Sylvain; Jamet, Éric; Roussarie, Vincent; Bosc, Laure; Chamard, Jean-Christophe

    2016-12-01

    Virtually silent electric vehicles (EVs) may pose a risk for pedestrians. This paper describes two studies that were conducted to assess the influence of different types of external sounds on EV detectability. In the first study, blindfolded participants had to detect an approaching EV with either no warning sounds at all or one of three types of sound we tested. In the second study, designed to replicate the results of the first one in an ecological setting, the EV was driven along a road and the experimenters counted the number of people who turned their heads in its direction. Results of the first study showed that adding external sounds improve EV detection, and modulating the frequency and increasing the pitch of these sounds makes them more effective. This improvement was confirmed in the ecological context. Consequently, pitch variation and frequency modulation should both be taken into account in future AVAS design. Copyright © 2016 Elsevier Ltd. All rights reserved.

  18. New approach to the perception of 3D shape based on veridicality, complexity, symmetry and volume.

    Science.gov (United States)

    Pizlo, Zygmunt; Sawada, Tadamasa; Li, Yunfeng; Kropatsch, Walter G; Steinman, Robert M

    2010-01-01

    This paper reviews recent progress towards understanding 3D shape perception made possible by appreciating the significant role that veridicality and complexity play in the natural visual environment. The ability to see objects as they really are "out there" is derived from the complexity inherent in the 3D object's shape. The importance of both veridicality and complexity was ignored in most prior research. Appreciating their importance made it possible to devise a computational model that recovers the 3D shape of an object from only one of its 2D images. This model uses a simplicity principle consisting of only four a priori constraints representing properties of 3D shapes, primarily their symmetry and volume. The model recovers 3D shapes from a single 2D image as well, and sometimes even better, than a human being. In the rare recoveries in which errors are observed, the errors made by the model and human subjects are very similar. The model makes no use of depth, surfaces or learning. Recent elaborations of this model include: (i) the recovery of the shapes of natural objects, including human and animal bodies with limbs in varying positions (ii) providing the model with two input images that allowed it to achieve virtually perfect shape constancy from almost all viewing directions. The review concludes with a comparison of some of the highlights of our novel, successful approach to the recovery of 3D shape from a 2D image with prior, less successful approaches.

  19. Age-period-cohort models using smoothing splines: a generalized additive model approach.

    Science.gov (United States)

    Jiang, Bei; Carriere, Keumhee C

    2014-02-20

    Age-period-cohort (APC) models are used to analyze temporal trends in disease or mortality rates, dealing with linear dependency among associated effects of age, period, and cohort. However, the nature of sparseness in such data has severely limited the use of APC models. To deal with these practical limitations and issues, we advocate cubic smoothing splines. We show that the methods of estimable functions proposed in the framework of generalized linear models can still be considered to solve the non-identifiability problem when the model fitting is within the framework of generalized additive models with cubic smoothing splines. Through simulation studies, we evaluate the performance of the cubic smoothing splines in terms of the mean squared errors of estimable functions. Our results support the use of cubic smoothing splines for APC modeling with sparse but unaggregated data from a Lexis diagram.

  20. Patient-specific in vitro models for hemodynamic analysis of congenital heart disease - Additive manufacturing approach.

    Science.gov (United States)

    Medero, Rafael; García-Rodríguez, Sylvana; François, Christopher J; Roldán-Alzate, Alejandro

    2017-03-21

    Non-invasive hemodynamic assessment of total cavopulmonary connection (TCPC) is challenging due to the complex anatomy. Additive manufacturing (AM) is a suitable alternative for creating patient-specific in vitro models for flow measurements using four-dimensional (4D) Flow MRI. These in vitro systems have the potential to serve as validation for computational fluid dynamics (CFD), simulating different physiological conditions. This study investigated three different AM technologies, stereolithography (SLA), selective laser sintering (SLS) and fused deposition modeling (FDM), to determine differences in hemodynamics when measuring flow using 4D Flow MRI. The models were created using patient-specific MRI data from an extracardiac TCPC. These models were connected to a perfusion pump circulating water at three different flow rates. Data was processed for visualization and quantification of velocity, flow distribution, vorticity and kinetic energy. These results were compared between each model. In addition, the flow distribution obtained in vitro was compared to in vivo. The results showed significant difference in velocities measured at the outlets of the models that required internal support material when printing. Furthermore, an ultrasound flow sensor was used to validate flow measurements at the inlets and outlets of the in vitro models. These results were highly correlated to those measured with 4D Flow MRI. This study showed that commercially available AM technologies can be used to create patient-specific vascular models for in vitro hemodynamic studies at reasonable costs. However, technologies that do not require internal supports during manufacturing allow smoother internal surfaces, which makes them better suited for flow analyses. Copyright © 2017 Elsevier Ltd. All rights reserved.

  1. Impact of biochar addition on thermal properties of a sandy soil: modelling approach

    Science.gov (United States)

    Usowicz, Boguslaw; Lipiec, Jerzy; Lukowski, Mateusz; Bis, Zbigniew; Marczewski, Wojciech; Usowicz, Jerzy

    2017-04-01

    Adding biochar can alter soil thermal properties and increase the water holding capacity and reduce the mineral soil fertilization. Biochar in the soil can determine the heat balance on the soil surface and the temperature distribution in the soil profile through changes in albedo and the thermal properties. Besides, amendment of soil with biochar results in improvement of water retention, fertility and pH that are of importance in sandy and acid soils, widely used in agriculture. In this study we evaluated the effects of wood-derived biochar (0, 10, 20, and 40 Mg ha-1) incorporated to a depth of 0-15 cm on the thermal conductivity, heat capacity, thermal diffusivity and porosity in sandy soil under field conditions. In addition, soil-biochar mixtures of various percentages of biochar were prepared to determine the thermal properties in function of soil water status and density in laboratory. It was shown that a small quantity of biochar added to the soil does not significantly affect all the thermal properties of the soil. Increasing biochar concentration significantly enhanced porosity and decreased thermal conductivity and diffusivity with different rate depending on soil water status. The soil thermal conductivity and diffusivity varied widely and non-linearly with water content for different biochar content and soil bulk density. However, the heat capacity increased with biochar addition and water content linearly and was greater at higher than lower soil water contents. The measured and literature thermal data were compared with those obtained from the analytic model of Zhang et al. (2013) and statistical-physical model (Usowicz et al., 2016) based on soil texture, biochar content, bulk density and water content.

  2. An additive combinatorics approach to the log-rank conjecture in communication complexity

    CERN Document Server

    Ben-Sasson, Eli; Zewi, Noga

    2011-01-01

    For a $\\{0,1\\}$-valued matrix $M$ let $\\rm{CC}(M)$ denote the deterministic communication complexity of the boolean function associated with $M$. The log-rank conjecture of Lov\\'{a}sz and Saks [FOCS 1988] states that $\\rm{CC}(M) \\leq \\log^c(\\rm{rank}(M))$ for some absolute constant $c$ where $\\rm{rank}(M)$ denotes the rank of $M$ over the field of real numbers. We show that $\\rm{CC}(M)\\leq c \\cdot \\rm{rank}(M)/\\log \\rm{rank}(M)$ for some absolute constant $c$, assuming a well-known conjecture from additive combinatorics known as the Polynomial Freiman-Ruzsa (PFR) conjecture. Our proof is based on the study of the "approximate duality conjecture" which was recently suggested by Ben-Sasson and Zewi [STOC 2011] and studied there in connection to the PFR conjecture. First we improve the bounds on approximate duality assuming the PFR conjecture. Then we use the approximate duality conjecture (with improved bounds) to get the aforementioned upper bound on the communication complexity of low-rank martices, where thi...

  3. Empirical Approach to Understanding the Fatigue Behavior of Metals Made Using Additive Manufacturing

    Science.gov (United States)

    Witkin, David B.; Albright, Thomas V.; Patel, Dhruv N.

    2016-08-01

    High-cycle fatigue measurements were performed on alloys prepared by powder-bed fusion additive manufacturing techniques. Selective laser melted (SLM) nickel-based superalloy 625 and electron beam melted (EBM) Ti-6Al-4V specimens were prepared as round fatigue specimens and tested with as-built surfaces at stress ratios of -1, 0.1 and 0.5. Data collected at R = -1 were used to construct Goodman diagrams that correspond closely to measured experimental data collected at R > 0. A second way to interpret the HCF data is based on the influence of surface roughness on fatigue, and approximate the surface feature size as a notch. On this basis, the data were interpreted using the fatigue notch factor k f and average stress models relating k f and stress concentration factor K t. The depth and root radius of surface features associated with fatigue crack initiation were used to estimate a K t of 2.8 for SLM 625. For Ti-6Al-4V, a direct estimate of K t from HCF data was not possible, but approximate values of k f based on HCF data and K t from crack initiation site geometry are found to explain other published EBM Ti-6Al-4V.

  4. A sustainable and resilient approach through biochar addition in wood polymer composites.

    Science.gov (United States)

    Das, Oisik; Sarmah, Ajit K; Bhattacharyya, Debes

    2015-04-15

    Biocomposites have been used for sustainability for a few years now and considerable advancements have been made to perfect the physical and mechanical properties. However, there still remain some considerable disadvantages (such as inferior mechanical strength, thickness swell, and rotting) which restrict their proper utilization in wider markets. Attempts have been made to remedy these drawbacks but still further investigation is required to address all the issues and alleviate as many shortcomings as possible. Additionally, concerns related to landfill gas emission prompted the necessity for effective utilization of organic wastes. Lignocellulosic wastes can be valorized by thermo-chemical conversion to form a carbonaceous and renewable material called biochar. Keeping these two problems in mind, a relatively novel idea is recommended for the manufacture of biocomposites where biochar made from pyrolysis of waste could be added with wood and plastic. It is expected to mitigate the general disadvantages of conventional wood plastic composites (WPCs) and at the same time manage landfill wastes giving rise to a potential new breed of improved next generation biocomposites. Furthermore, a 'resilient' perspective is conferred where the long term viability of the state-of-the-art product could be ensured. Copyright © 2015 Elsevier B.V. All rights reserved.

  5. A novel approach in organic waste utilization through biochar addition in wood/polypropylene composites

    Energy Technology Data Exchange (ETDEWEB)

    Das, Oisik [Department of Civil and Environmental Engineering, University of Auckland, Auckland 1142 (New Zealand); Sarmah, Ajit K., E-mail: a.sarmah@auckland.ac.nz [Department of Civil and Environmental Engineering, University of Auckland, Auckland 1142 (New Zealand); Bhattacharyya, Debes [Department of Mechanical Engineering, Center for Advanced Composite Materials, University of Auckland, Auckland 1142 (New Zealand)

    2015-04-15

    Highlights: • Biochar made from waste wood was added with wood polypropylene composites. • 24% biochar gave the best mechanical properties. • 6% biochar had no effect on physico-mechanical properties of composites. • Coupling agent remained unreacted in composites having higher amount of biochar. - Abstract: In an attempt to concurrently address the issues related to landfill gas emission and utilization of organic wastes, a relatively novel idea is introduced to develop biocomposites where biochar made from pyrolysis of waste wood (Pinus radiata) is added with the same wood, plastic/polymer (polypropylene) and maleated anhydride polypropylene (MAPP). Experiments were conducted by manufacturing wood and polypropylene composites (WPCs) mixed with 6 wt%, 12 wt%, 18 wt%, 24 wt%, and 30 wt% biochar. Though 6 wt% addition had similar properties to that of the control (composite without biochar), increasing biochar content to 24 wt% improved the composite’s tensile/flexural strengths and moduli. The biochar, having high surface area due to fine particles and being highly carbonised, acted as reinforcing filler in the biocomposite. Composites having 12 wt% and 18 wt% of biochar were found to be the most ductile and thermally stable, respectively. This study demonstrates that, WPCs added with biochar has good potential to mitigate wastes while simultaneously producing biocomposites having properties that might be suited for various end applications.

  6. Aquatic toxicity and ecological risk assessment of seven parabens: Individual and additive approach.

    Science.gov (United States)

    Yamamoto, Hiroshi; Tamura, Ikumi; Hirata, Yoshiko; Kato, Jun; Kagota, Keiichiro; Katsuki, Shota; Yamamoto, Atsushi; Kagami, Yoshihiro; Tatarazako, Norihisa

    2011-12-01

    In the present study, aquatic concentrations of seven parabens were determined in urban streams highly affected by treated or untreated domestic sewage in Tokushima and Osaka, Japan. The detected highest concentrations were 670, 207, and 163ngl(-1) for methylparaben, n-propylparaben, and n-butylparaben, respectively in sampling sites with watershed area of no sewer system in Tokushima. Conventional acute/chronic toxicity tests were conducted using medaka (Oryzias latipes), Daphnia magna, and Psuedokirchneriella subcapitata for four parabens, which was consistent with our previous study on three parabens, n-butylparaben, i-butylparaben, and benzylparaben. The aquatic toxicity on fish, daphnia, and algae was weaker for the parabens with a shorter alkyl chain than those with a longer alkyl chain as predicted by their hydrophobicity. Medaka vitellogenin assays and DNA microarray analysis were carried out for methylparaben and found induction of significant vitellogenin in male medaka at 630μgl(-1) of methylparaben, while the expression levels of genes encoding proteins such as choriogenin and vitellogenin increased for concentrations at 10μgl(-1) of methylparaben. Measured environmental concentrations (MECs) of seven parabens in Tokushima and Osaka were divided by predicted no effect concentrations (PNECs) and hazard quotient (MEC/PNEC) was determined for individual parabens. The MEC/PNEC was highest for n-propylparaben and was 0.010 followed by n-butylparaben (max. of 0.0086) and methylparaben (max. of 0.0042). The sum of the MEC/PNEC for the seven parabens was 0.0049. Equivalence factors were assigned for each paraben on the basis of the toxicity of n-butylparaben for each species, and n-butylparaben equivalence was calculated for the measured environmental concentrations. The MEC/PNEC approach was also conducted for the n-butylparaben-based equivalence values. The maximum MEC/PNEC was 0.018, which is lower than the trigger level for further detailed study such as

  7. Linking flood peak, flood volume and inundation extent: a DEM-based approach

    Science.gov (United States)

    Rebolho, Cédric; Furusho-Percot, Carina; Blaquière, Simon; Brettschneider, Marco; Andréassian, Vazken

    2017-04-01

    Traditionally, flood inundation maps are computed based on the Shallow Water Equations (SWE) in one or two dimensions, with various simplifications that have proved to give good results. However, the complexity of the SWEs often requires a numerical resolution which can need long computing time, as well as detailed cross section data: this often results in restricting these models to rather small areas abundant with high quality data. This, along with the necessity for fast inundation mapping, are the reason why rapid inundation models are being designed, working for (almost) any river with a minimum amount of data and, above all, easily available data. Our model tries to follow this path by using a 100m DEM over France from which are extracted a drainage network and the associated drainage areas. It is based on two pre-existing methods: (1) SHYREG (Arnaud et al.,2013), a regionalized approach used to calculate the 2-year and 10-year flood quantiles (used as approximated bankfull flow and maximum discharge, respectively) for each river pixel of the DEM (below a 10 000 km2 drainage area) and (2) SOCOSE (Mailhol,1980), which gives, amongst other things, an empirical formula of a characteristic flood duration (for each pixel) based on catchment area, average precipitation and temperature. An overflow volume for each river pixel is extracted from a triangular shaped synthetic hydrograph designed with SHYREG quantiles and SOCOSE flood duration. The volume is then spread from downstream to upstream one river pixel at a time. When the entire hydrographic network is processed, the model stops and generates a map of potential inundation area associated with the 10-year flood quantile. Our model can also be calibrated using past-events inundation maps by adjusting two parameters, one which modifies the overflow duration, and the other, equivalent to a minimum drainage area for river pixels to be flooded. Thus, in calibration on a sample of 42 basins, the first draft of the

  8. A statistical approach to the initial volume problem in Single Particle Analysis by Electron Microscopy.

    Science.gov (United States)

    Sorzano, C O S; Vargas, J; de la Rosa-Trevín, J M; Otón, J; Álvarez-Cabrera, A L; Abrishami, V; Sesmero, E; Marabini, R; Carazo, J M

    2015-03-01

    Cryo Electron Microscopy is a powerful Structural Biology technique, allowing the elucidation of the three-dimensional structure of biological macromolecules. In particular, the structural study of purified macromolecules -often referred as Single Particle Analysis(SPA)- is normally performed through an iterative process that needs a first estimation of the three-dimensional structure that is progressively refined using experimental data. It is well-known the local optimisation nature of this refinement, so that the initial choice of this first structure may substantially change the final result. Computational algorithms aiming to providing this first structure already exist. However, the question is far from settled and more robust algorithms are still needed so that the refinement process can be performed with sufficient guarantees. In this article we present a new algorithm that addresses the initial volume problem in SPA by setting it in a Weighted Least Squares framework and calculating the weights through a statistical approach based on the cumulative density function of different image similarity measures. We show that the new algorithm is significantly more robust than other state-of-the-art algorithms currently in use in the field. The algorithm is available as part of the software suite Xmipp (http://xmipp.cnb.csic.es) and Scipion (http://scipion.cnb.csic.es) under the name "Significant".

  9. Ion Recognition Approach to Volume Reduction of Alkaline Tank Waste by Separation of Sodium Salts

    Energy Technology Data Exchange (ETDEWEB)

    Moyer, Bruce A.; Bonnesen, Peter V.; Custelcean, Radu; Delmau, Laetitia H.; Engle, Nancy L.; Kang, Hyun-Ah; Keever, Tamara J.; Marchand, Alan P.; Gadthula, Srinivas; Gore, Vinayak K.; Huang, Zilin; Sivappa, Rasapalli; Tirunahari, Pavan K.; Levitskaia, Tatiana G.; Lumetta, Gregg J.

    2005-09-26

    The purpose of this research involving collaboration between Oak Ridge National Laboratory (ORNL) and Pacific Northwest National Laboratory (PNNL) is to explore new approaches to the separation of sodium hydroxide, sodium nitrate, and other sodium salts from high-level alkaline tank waste. The principal potential benefit is a major reduction in disposed waste volume, obviating the building of expensive new waste tanks and reducing the costs of vitrification. Principles of ion recognition are being researched toward discovery of liquid-liquid extraction systems that selectively separate sodium hydroxide and sodium nitrate from other waste components. The successful concept of pseudo hydroxide extraction using fluorinated alcohols and phenols is being developed at ORNL and PNNL toward a greater understanding of the controlling equilibria, role of solvation, and of synergistic effects involving crown ethers. Synthesis efforts are being directed toward enhanced sodium binding by crown ethers, both neutral and proton-ionizable. Studies with real tank waste at PNNL will provide feedback toward solvent compositions that have promising properties.

  10. A Direct Approach Based on C2-IULOWA Operator for Group Decision Making with Uncertain Additive Linguistic Preference Relations

    Directory of Open Access Journals (Sweden)

    Ding-Hong Peng

    2013-01-01

    Full Text Available With respect to group decision making (GDM problem with uncertain additive linguistic preference relations (UALPRs, we investigate the efficient aggregation of the uncertain additive linguistic preference information. First, we introduce two measures to assess the consistency level and the consensus level of uncertain additive linguistic preference information, respectively, and study some of their desirable properties. Then, based on both the two measures, we propose a coinduced uncertain linguistic ordered weighted averaging (IULOWA operator, called the consistency and consensus coinduced uncertain linguistic ordered weighted averaging (C2-IULOWA operator, to aggregate individual uncertain additive linguistic preference information, in which the consistency level and the consensus level synergistically serve as inducing variables and then guide the determination of the associated weights. We have proved the collective uncertain linguistic preference information aggregated by the C2-IULOWA operator that can maintain the fundamental properties of preference relation, such as indifference, reciprocity, and transitivity. By using the C2-IULOWA operator, we develop a direct GDM approach with UALPRs. Finally, an illustrative example on the selection of chief quality officer is used to demonstrate the effectiveness and rationalitly of the developed approach.

  11. Conceptual approach for an in-line quality control system in Additive Manufacturing Powder Bed Fusion processes

    Directory of Open Access Journals (Sweden)

    Fulga Simina

    2017-01-01

    Full Text Available Additive Manufacturing is one of the genuine hopes for the forth industrial revolution since digital data is controlling the whole layered production process. At the same time the geometric freedom and tool-free production assures a high degree of individualisation. But to be the driving force behind a new industrial revolution, a qualification of additive manufacturing processes is necessary so that the resulting products meet the required quality and safety standards in the different fields of application such as in handling technology or medical technology. This paper will discuss a conceptual approach for the development of an in-line quality control system in Additive Manufacturing Powder Bed Fusion processes using the example of the Selective Laser Sintering process.

  12. Understanding the acoustics of Papal Basilicas in Rome by means of a coupled-volumes approach

    Science.gov (United States)

    Martellotta, Francesco

    2016-11-01

    The paper investigates the acoustics of the four World-famous Papal Basilicas in Rome, namely Saint Peter's, St. John Lateran's, St. Paul's outside the Walls, and Saint Mary's Major. They are characterized by different dimensions, materials, and architectural features, as well as by a certain number of similarities. In addition, their complexity determines significant variation in their acoustics depending on the relative position of source and receivers. A detailed set of acoustic measurements was carried out in each church, using both spatial (B-format) and binaural microphones, and determining the standard ISO 3382 descriptors. The results are analyzed in relation to the architectural features, pointing out the differences observed in terms of listening experience. Finally, in order to explain some of the results found in energy-based parameters, the churches were analyzed as a system of acoustically coupled volumes. The latter explained most of the anomalies observed in the distribution of acoustic parameters, while showing at the same time that secondary spaces (aisles, chapels) play a different role depending on the amount of sound absorption located in the main nave.

  13. Single breath-hold 3D measurement of left atrial volume using compressed sensing cardiovascular magnetic resonance and a non-model-based reconstruction approach.

    Science.gov (United States)

    Vardoulis, Orestis; Monney, Pierre; Bermano, Amit; Vaxman, Amir; Gotsman, Craig; Schwitter, Janine; Stuber, Matthias; Stergiopulos, Nikolaos; Schwitter, Juerg

    2015-06-11

    Left atrial (LA) dilatation is associated with a large variety of cardiac diseases. Current cardiovascular magnetic resonance (CMR) strategies to measure LA volumes are based on multi-breath-hold multi-slice acquisitions, which are time-consuming and susceptible to misregistration. To develop a time-efficient single breath-hold 3D CMR acquisition and reconstruction method to precisely measure LA volumes and function. A highly accelerated compressed-sensing multi-slice cine sequence (CS-cineCMR) was combined with a non-model-based 3D reconstruction method to measure LA volumes with high temporal and spatial resolution during a single breath-hold. This approach was validated in LA phantoms of different shapes and applied in 3 patients. In addition, the influence of slice orientations on accuracy was evaluated in the LA phantoms for the new approach in comparison with a conventional model-based biplane area-length reconstruction. As a reference in patients, a self-navigated high-resolution whole-heart 3D dataset (3D-HR-CMR) was acquired during mid-diastole to yield accurate LA volumes. Phantom studies. LA volumes were accurately measured by CS-cineCMR with a mean difference of -4.73 ± 1.75 ml (-8.67 ± 3.54%, r2 = 0.94). For the new method the calculated volumes were not significantly different when different orientations of the CS-cineCMR slices were applied to cover the LA phantoms. Long-axis "aligned" vs "not aligned" with the phantom long-axis yielded similar differences vs the reference volume (-4.87 ± 1.73 ml vs. -4.45 ± 1.97 ml, p = 0.67) and short-axis "perpendicular" vs. "not-perpendicular" with the LA long-axis (-4.72 ± 1.66 ml vs. -4.75 ± 2.13 ml; p = 0.98). The conventional bi-plane area-length method was susceptible for slice orientations (p = 0.0085 for the interaction of "slice orientation" and "reconstruction technique", 2-way ANOVA for repeated measures). To use the 3D-HR-CMR as the reference for LA volumes

  14. An Approach to the Use of Depth Cameras for Weed Volume Estimation

    Science.gov (United States)

    Andújar, Dionisio; Dorado, José; Fernández-Quintanilla, César; Ribeiro, Angela

    2016-01-01

    The use of depth cameras in precision agriculture is increasing day by day. This type of sensor has been used for the plant structure characterization of several crops. However, the discrimination of small plants, such as weeds, is still a challenge within agricultural fields. Improvements in the new Microsoft Kinect v2 sensor can capture the details of plants. The use of a dual methodology using height selection and RGB (Red, Green, Blue) segmentation can separate crops, weeds, and soil. This paper explores the possibilities of this sensor by using Kinect Fusion algorithms to reconstruct 3D point clouds of weed-infested maize crops under real field conditions. The processed models showed good consistency among the 3D depth images and soil measurements obtained from the actual structural parameters. Maize plants were identified in the samples by height selection of the connected faces and showed a correlation of 0.77 with maize biomass. The lower height of the weeds made RGB recognition necessary to separate them from the soil microrelief of the samples, achieving a good correlation of 0.83 with weed biomass. In addition, weed density showed good correlation with volumetric measurements. The canonical discriminant analysis showed promising results for classification into monocots and dictos. These results suggest that estimating volume using the Kinect methodology can be a highly accurate method for crop status determination and weed detection. It offers several possibilities for the automation of agricultural processes by the construction of a new system integrating these sensors and the development of algorithms to properly process the information provided by them. PMID:27347972

  15. An Approach to the Use of Depth Cameras for Weed Volume Estimation

    Directory of Open Access Journals (Sweden)

    Dionisio Andújar

    2016-06-01

    Full Text Available The use of depth cameras in precision agriculture is increasing day by day. This type of sensor has been used for the plant structure characterization of several crops. However, the discrimination of small plants, such as weeds, is still a challenge within agricultural fields. Improvements in the new Microsoft Kinect v2 sensor can capture the details of plants. The use of a dual methodology using height selection and RGB (Red, Green, Blue segmentation can separate crops, weeds, and soil. This paper explores the possibilities of this sensor by using Kinect Fusion algorithms to reconstruct 3D point clouds of weed-infested maize crops under real field conditions. The processed models showed good consistency among the 3D depth images and soil measurements obtained from the actual structural parameters. Maize plants were identified in the samples by height selection of the connected faces and showed a correlation of 0.77 with maize biomass. The lower height of the weeds made RGB recognition necessary to separate them from the soil microrelief of the samples, achieving a good correlation of 0.83 with weed biomass. In addition, weed density showed good correlation with volumetric measurements. The canonical discriminant analysis showed promising results for classification into monocots and dictos. These results suggest that estimating volume using the Kinect methodology can be a highly accurate method for crop status determination and weed detection. It offers several possibilities for the automation of agricultural processes by the construction of a new system integrating these sensors and the development of algorithms to properly process the information provided by them.

  16. An Approach to the Use of Depth Cameras for Weed Volume Estimation.

    Science.gov (United States)

    Andújar, Dionisio; Dorado, José; Fernández-Quintanilla, César; Ribeiro, Angela

    2016-06-25

    The use of depth cameras in precision agriculture is increasing day by day. This type of sensor has been used for the plant structure characterization of several crops. However, the discrimination of small plants, such as weeds, is still a challenge within agricultural fields. Improvements in the new Microsoft Kinect v2 sensor can capture the details of plants. The use of a dual methodology using height selection and RGB (Red, Green, Blue) segmentation can separate crops, weeds, and soil. This paper explores the possibilities of this sensor by using Kinect Fusion algorithms to reconstruct 3D point clouds of weed-infested maize crops under real field conditions. The processed models showed good consistency among the 3D depth images and soil measurements obtained from the actual structural parameters. Maize plants were identified in the samples by height selection of the connected faces and showed a correlation of 0.77 with maize biomass. The lower height of the weeds made RGB recognition necessary to separate them from the soil microrelief of the samples, achieving a good correlation of 0.83 with weed biomass. In addition, weed density showed good correlation with volumetric measurements. The canonical discriminant analysis showed promising results for classification into monocots and dictos. These results suggest that estimating volume using the Kinect methodology can be a highly accurate method for crop status determination and weed detection. It offers several possibilities for the automation of agricultural processes by the construction of a new system integrating these sensors and the development of algorithms to properly process the information provided by them.

  17. A new approach for volume reconstruction in TomoPIV with the alternating direction method of multipliers

    Science.gov (United States)

    Barbu, Ioana; Herzet, Cédric

    2016-10-01

    We adapt and import into the TomoPIV scenery a fast algorithm for solving the volume reconstruction problem. Our approach is based on the reformulation of the volume reconstruction task as a constrained optimization problem and the resort to the ‘alternating directions method of multipliers’ (ADMM). The inherent primal-dual algorithm is summarized in this article to solve the optimization problem related to the TomoPIV. In particular, the general formulation of the volume reconstruction problem considered in this paper allows one to: (i) take explicitly into account the level of the noise affecting the data; (ii) account for both the nonnegativity and the sparsity of the solution. Experiments on a numerical TomoPIV benchmark show that the proposed framework is a serious contender for the state-of-the-art.

  18. Different approaches to synovial membrane volume determination by magnetic resonance imaging: manual versus automated segmentation

    DEFF Research Database (Denmark)

    Østergaard, Mikkel

    1997-01-01

    Automated fast (5-20 min) synovial membrane volume determination by MRI, based on pre-set post-gadolinium-DTPA enhancement thresholds, was evaluated as a substitute for a time-consuming (45-120 min), previously validated, manual segmentation method. Twenty-nine knees [rheumatoid arthritis (RA) 13...... or synovial membrane volume, e.g. no systematic errors were found. The inter-MRI variation, evaluated in three knees and three wrists, was higher than by manual segmentation, particularly due to sensitivity to malalignment artefacts. Examination of test objects proved the high accuracy of the general...... methodology for volume determinations (maximal error 6.3%). Preceded by the determination of reproducibility and the optimal threshold at the available MR unit, automated 'threshold' segmentation appears to be acceptable when changes rather than absolute values of synovial membrane volumes are most important...

  19. The influence of trading volume on market efficiency: The DCCA approach

    Science.gov (United States)

    Sukpitak, Jessada; Hengpunya, Varagorn

    2016-09-01

    For a single market, the cross-correlation between market efficiency and trading volume, which is an indicator of market liquidity, is attentively analysed. The study begins with creating time series of market efficiency by applying time-varying Hurst exponent with one year sliding window to daily closing prices. The time series of trading volume corresponding to the same time period used for the market efficiency is derived from one year moving average of daily trading volume. Subsequently, the detrended cross-correlation coefficient is employed to quantify the degree of cross-correlation between the two time series. It was found that values of cross-correlation coefficient of all considered stock markets are close to 0 and are clearly out of range in which correlation being considered significant in almost every time scale. Obtained results show that the market liquidity in term of trading volume hardly has effect on the market efficiency.

  20. Interactive volume exploration of petascale microscopy data streams using a visualization-driven virtual memory approach

    KAUST Repository

    Hadwiger, Markus

    2012-12-01

    This paper presents the first volume visualization system that scales to petascale volumes imaged as a continuous stream of high-resolution electron microscopy images. Our architecture scales to dense, anisotropic petascale volumes because it: (1) decouples construction of the 3D multi-resolution representation required for visualization from data acquisition, and (2) decouples sample access time during ray-casting from the size of the multi-resolution hierarchy. Our system is designed around a scalable multi-resolution virtual memory architecture that handles missing data naturally, does not pre-compute any 3D multi-resolution representation such as an octree, and can accept a constant stream of 2D image tiles from the microscopes. A novelty of our system design is that it is visualization-driven: we restrict most computations to the visible volume data. Leveraging the virtual memory architecture, missing data are detected during volume ray-casting as cache misses, which are propagated backwards for on-demand out-of-core processing. 3D blocks of volume data are only constructed from 2D microscope image tiles when they have actually been accessed during ray-casting. We extensively evaluate our system design choices with respect to scalability and performance, compare to previous best-of-breed systems, and illustrate the effectiveness of our system for real microscopy data from neuroscience. © 1995-2012 IEEE.

  1. Differentiating SIADH from Cerebral/Renal Salt Wasting: Failure of the Volume Approach and Need for a New Approach to Hyponatremia.

    Science.gov (United States)

    Maesaka, John K; Imbriano, Louis; Mattana, Joseph; Gallagher, Dympna; Bade, Naveen; Sharif, Sairah

    2014-12-08

    Hyponatremia is the most common electrolyte abnormality. Its diagnostic and therapeutic approaches are in a state of flux. It is evident that hyponatremic patients are symptomatic with a potential for serious consequences at sodium levels that were once considered trivial. The recommendation to treat virtually all hyponatremics exposes the need to resolve the diagnostic and therapeutic dilemma of deciding whether to water restrict a patient with the syndrome of inappropriate antidiuretic hormone secretion (SIADH) or administer salt and water to a renal salt waster. In this review, we briefly discuss the pathophysiology of SIADH and renal salt wasting (RSW), and the difficulty in differentiating SIADH from RSW, and review the origin of the perceived rarity of RSW, as well as the value of determining fractional excretion of urate (FEurate) in differentiating both syndromes, the high prevalence of RSW which highlights the inadequacy of the volume approach to hyponatremia, the importance of changing cerebral salt wasting to RSW, and the proposal to eliminate reset osmostat as a subtype of SIADH, and finally propose a new algorithm to replace the outmoded volume approach by highlighting FEurate. This algorithm eliminates the need to assess the volume status with less reliance on determining urine sodium concentration, plasma renin, aldosterone and atrial/brain natriuretic peptide or the BUN to creatinine ratio.

  2. Differentiating SIADH from Cerebral/Renal Salt Wasting: Failure of the Volume Approach and Need for a New Approach to Hyponatremia

    Directory of Open Access Journals (Sweden)

    John K. Maesaka

    2014-12-01

    Full Text Available Hyponatremia is the most common electrolyte abnormality. Its diagnostic and therapeutic approaches are in a state of flux. It is evident that hyponatremic patients are symptomatic with a potential for serious consequences at sodium levels that were once considered trivial. The recommendation to treat virtually all hyponatremics exposes the need to resolve the diagnostic and therapeutic dilemma of deciding whether to water restrict a patient with the syndrome of inappropriate antidiuretic hormone secretion (SIADH or administer salt and water to a renal salt waster. In this review, we briefly discuss the pathophysiology of SIADH and renal salt wasting (RSW, and the difficulty in differentiating SIADH from RSW, and review the origin of the perceived rarity of RSW, as well as the value of determining fractional excretion of urate (FEurate in differentiating both syndromes, the high prevalence of RSW which highlights the inadequacy of the volume approach to hyponatremia, the importance of changing cerebral salt wasting to RSW, and the proposal to eliminate reset osmostat as a subtype of SIADH, and finally propose a new algorithm to replace the outmoded volume approach by highlighting FEurate. This algorithm eliminates the need to assess the volume status with less reliance on determining urine sodium concentration, plasma renin, aldosterone and atrial/brain natriuretic peptide or the BUN to creatinine ratio.

  3. Data regarding hydraulic fracturing distributions and treatment fluids, additives, proppants, and water volumes applied to wells drilled in the United States from 1947 through 2010

    Science.gov (United States)

    Gallegos, Tanya J.; Varela, Brian A.

    2015-01-01

    Comprehensive, published, and publicly available data regarding the extent, location, and character of hydraulic fracturing in the United States are scarce. The objective of this data series is to publish data related to hydraulic fracturing in the public domain. The spreadsheets released with this data series contain derivative datasets aggregated temporally and spatially from the commercial and proprietary IHS database of U.S. oil and gas production and well data (IHS Energy, 2011). These datasets, served in 21 spreadsheets in Microsoft Excel (.xlsx) format, outline the geographical distributions of hydraulic fracturing treatments and associated wells (including well drill-hole directions) as well as water volumes, proppants, treatment fluids, and additives used in hydraulic fracturing treatments in the United States from 1947 through 2010. This report also describes the data—extraction/aggregation processing steps, field names and descriptions, field types and sources. An associated scientific investigation report (Gallegos and Varela, 2014) provides a detailed analysis of the data presented in this data series and comparisons of the data and trends to the literature.

  4. Multiscale approaches for simulation of nucleation, growth, and additive chemistry during electrochemical deposition of thin metal films

    Science.gov (United States)

    Stephens, Ryan Mark

    Molecularly engineered deposition processes require computational algorithms that efficiently capture phenomena present at widely varying length and time scales. In this work, the island dynamics method was applied to simulation of kinetically-limited metal nucleation and growth by electrodeposition in the presence of additives. The model included additive kinetics, surface diffusion of adatoms, nucleation, and growth. The model was demonstrated for copper deposition in acid sulfate electrolyte containing [bis(3-sulfopropyl)disulfide], polyethylene glycol, and chloride. Simulation results were compared with kinetic Monte Carlo (KMC) calculations and found to be within 1% for fractional coverage values, and within 10% for nucleation density. The computational time was more than 10X faster than comparable KMC simulations over the range studied. The island dynamics algorithm was applied to the electrodeposition of a metal onto a substrate initially configured with an array of hemispherical seed clusters. It was found that the presence of chloride in the model additive system caused high densities of nuclei on the substrate surrounding the initial seed clusters, which led to the formation of a continuous thin metal film. Simulations carried out under low-chloride conditions resulted in the growth only of the initial seed clusters, without significant nucleation or thin film formation. Additional phenomena were explored by linking the molecular scale island dynamics algorithm to a continuum model that described the migration and diffusion in the diffusion layer near the electrode surface. The multiscale linkage allowed simulation of nucleation, growth, and additive chemistry under mass transport limited conditions, including the formation of nucleation exclusion zones surrounding growing nuclei. A two-step approach was used to calculate the spatial distribution of nucleation events on an electrode undergoing deposition by electrolysis under the influence of mass

  5. A mathematical approach to optimal selection of dose values in the additive dose method of ERP dosimetry

    Energy Technology Data Exchange (ETDEWEB)

    Hayes, R.B.; Haskell, E.H.; Kenner, G.H. [Utah Univ., Salt Lake City, UT (United States)

    1996-01-01

    Additive dose methods commonly used in electron paramagnetic resonance (EPR) dosimetry are time consuming and labor intensive. We have developed a mathematical approach for determining optimal spacing of applied doses and the number of spectra which should be taken at each dose level. Expected uncertainitites in the data points are assumed to be normally distributed with a fixed standard deviation and linearity of dose response is also assumed. The optimum spacing and number of points necessary for the minimal error can be estimated, as can the likely error in the resulting estimate. When low doses are being estimated for tooth enamel samples the optimal spacing is shown to be a concentration of points near the zero dose value with fewer spectra taken at a single high dose value within the range of known linearity. Optimization of the analytical process results in increased accuracy and sample throughput.

  6. FORECASTING CHINA'S FOREIGN TRADE VOLUME WITH A KERNEL-BASED HYBRID EC-ONOMETRIC-AI ENSEMBLE LEARNING APPROACH

    Institute of Scientific and Technical Information of China (English)

    Lean YU; Shouyang WANG; Kin Keung LAI

    2008-01-01

    Due to the complexity of economic system and the interactive effects between all kinds of economic variables and foreign trade, it is not easy to predict foreign trade volume. However, the difficulty in predicting foreign trade volume is usually attributed to the limitation of many conventional forecasting models. To improve the prediction performance, the study proposes a novel kernel-based ensemble learning approach hybridizing econometric models and artificial intelligence (AI) models to predict China's foreign trade volume. In the proposed approach, an important econometric model, the co-integration-based error correction vector auto-regression (EC-VAR) model is first used to capture the impacts of all kinds of economic variables on Chinese foreign trade from a multivariate linear anal-ysis perspective. Then an artificial neural network (ANN) based EC-VAR model is used to capture the nonlinear effects of economic variables on foreign trade from the nonlinear viewpoint. Subsequently, for incorporating the effects of irregular events on foreign trade, the text mining and expert's judgmental adjustments are also integrated into the nonlinear ANN-based EC-VAR model. Finally, all kinds of economic variables, the outputs of linear and nonlinear EC-VAR models and judgmental adjustment model are used as input variables of a typical kernel-based support vector regression (SVR) for en-semble prediction purpose. For illustration, the proposed kernel-based ensemble learning methodology hybridizing econometric techniques and AI methods is applied to China's foreign trade volume predic-tion problem. Experimental results reveal that the hybrid econometric-AI ensemble learning approach can significantly improve the prediction performance over other linear and nonlinear models listed in this study.

  7. Research Papers Sponsored by the Commission on Private Philanthropy and Public Needs. Volume II: Philanthropic Fields of Interest, Part II-Additional Perspectives.

    Science.gov (United States)

    Department of the Treasury, Washington, DC.

    Twelve papers discuss future changes and trends in philanthropic giving and activities. The report is Volume II, Part II of a five volume series examining the relationship between nonprofit institutions and their donors. The opening paper reviews the needs for better definition of the government's role in contracting and grant making, and for…

  8. Energy data visualisation requires additional approaches to continue to be relevant in a world with greater low-carbon generation.

    Directory of Open Access Journals (Sweden)

    I.A. Grant Wilson

    2016-08-01

    Full Text Available The hypothesis described in this article proposes that energy visualisation diagrams commonly used need additional changes to continue to be relevant in a world with greater low-carbon generation. The diagrams that display national energy data are influenced by the properties of the type of energy being displayed, which in most cases has historically meant fossil fuels, nuclear fuels or hydro. As many energy systems throughout the world increase their use of electricity from wind or solar based renewables, a more granular display of energy data in the time domain is required. This article also introduces the shared axes energy diagram that provides a simple and powerful way in which to compare the scale and seasonality of the demands and supplies of an energy system. This aims to complement rather than replace existing diagrams, and has an additional benefit of promoting a whole systems approach to energy systems, as differing energy vectors such as natural gas, transport fuels, and electricity can all be displayed together. This in particular, is useful to both policy makers and to industry, to build a visual foundation for a whole systems narrative, which provides a basis for discussion of the synergies and opportunities across and between different energy vectors and demands. The diagram’s ability to wrap a sense of scale around a whole energy system in a simple way is thought to explain its growing popularity.

  9. New Approach to Purging Monitoring Wells: Lower Flow Rates Reduce Required Purging Volumes and Sample Turbidity

    Science.gov (United States)

    It is generally accepted that monitoring wells must be purged to access formation water to obtain “representative” ground water quality samples. Historically anywhere from 3 to 5 well casing volumes have been removed prior to sample collection to evacuate the standing well water...

  10. TRADABLE CREDITS FOR STORM WATER VOLUME: AN ALTERNATIVE APPROACH FOR SUSTAINABLE URBAN WATERSHED MANAGEMENT

    Science.gov (United States)

    The increased storm water runoff rate and volume caused by urbanization, and their detrimental effects on stream habitat and morphology, is well documented. In most cases, current storm water management policies are focused on attenuating peak flow rates. While these policies may...

  11. Prediction of Currency Volume Issued in Taiwan Using a Hybrid Artificial Neural Network and Multiple Regression Approach

    Directory of Open Access Journals (Sweden)

    Yuehjen E. Shao

    2013-01-01

    Full Text Available Because the volume of currency issued by a country always affects its interest rate, price index, income levels, and many other important macroeconomic variables, the prediction of currency volume issued has attracted considerable attention in recent years. In contrast to the typical single-stage forecast model, this study proposes a hybrid forecasting approach to predict the volume of currency issued in Taiwan. The proposed hybrid models consist of artificial neural network (ANN and multiple regression (MR components. The MR component of the hybrid models is established for a selection of fewer explanatory variables, wherein the selected variables are of higher importance. The ANN component is then designed to generate forecasts based on those important explanatory variables. Subsequently, the model is used to analyze a real dataset of Taiwan's currency from 1996 to 2011 and twenty associated explanatory variables. The prediction results reveal that the proposed hybrid scheme exhibits superior forecasting performance for predicting the volume of currency issued in Taiwan.

  12. A volume-amending method to improve mass conservation of level set approach for incompressible two-phase flows

    Institute of Scientific and Technical Information of China (English)

    LI XiangYang; WANG YueFa; YU GengZhi; YANG Chao; MAO ZaiSha

    2008-01-01

    A volume-amending method is developed both to keep the level set function as an algebraic distance function and to preserve the bubble mass in a level set approach for incompressible two-phase flows with the significantly deformed free interface. After the traditional reinitialization procedure, a vol-ume-amending method is added for correcting the position of the interface according to mass loss/gain error until the mass error falls in the allowable range designated in advance. The level set approach with this volume-amending method incorporated has been validated by three test cases: the motion of a single axisymmetrical bubble or drop in liquid, the motion of a two-dimensional water drop falling through the air into a water pool, and the interactional motion of two buoyancy-driven three-dimensional deformable bubbles. The computational results with this volume-amending method in-corporated are in good agreement with the reported experimental data and the mass is well preserved in all cases.

  13. A volume-amending method to improve mass conservation of level set approach for incompressible two-phase flows

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    A volume-amending method is developed both to keep the level set function as an algebraic distance function and to preserve the bubble mass in a level set approach for incompressible two-phase flows with the significantly deformed free interface. After the traditional reinitialization procedure, a vol-ume-amending method is added for correcting the position of the interface according to mass loss/gain error until the mass error falls in the allowable range designated in advance. The level set approach with this volume-amending method incorporated has been validated by three test cases: the motion of a single axisymmetrical bubble or drop in liquid, the motion of a two-dimensional water drop falling through the air into a water pool, and the interactional motion of two buoyancy-driven three- dimensional deformable bubbles. The computational results with this volume-amending method in-corporated are in good agreement with the reported experimental data and the mass is well preserved in all cases.

  14. Evaluation of a Novel Approach for Automatic Volume Determination of Glioblastomas Based on Several Manual Expert Segmentations

    CERN Document Server

    Egger, Jan; Kuhnt, Daniela; Carl, Barbara; Kappus, Christoph; Freisleben, Bernd; Nimsky, Christopher

    2011-01-01

    The glioblastoma multiforme is the most common malignant primary brain tumor and is one of the highest malignant human neoplasms. During the course of disease, the evaluation of tumor volume is an essential part of the clinical follow-up. However, manual segmentation for acquisition of tumor volume is a time-consuming process. In this paper, a new approach for the automatic segmentation and volume determination of glioblastomas (glioblastoma multiforme) is presented and evaluated. The approach uses a user-defined seed point inside the glioma to set up a directed 3D graph. The nodes of the graph are obtained by sampling along rays that are sent through the surface points of a polyhedron. After the graph has been constructed, the minimal s-t cut is calculated to separate the glioblastoma from the background. For evaluation, 12 Magnetic Resonance Imaging (MRI) data sets were manually segmented slice by slice, by neurosurgeons with several years of experience in the resection of gliomas. Afterwards, the manual se...

  15. Constrained reaction volume approach for studying chemical kinetics behind reflected shock waves

    KAUST Repository

    Hanson, Ronald K.

    2013-09-01

    We report a constrained-reaction-volume strategy for conducting kinetics experiments behind reflected shock waves, achieved in the present work by staged filling in a shock tube. Using hydrogen-oxygen ignition experiments as an example, we demonstrate that this strategy eliminates the possibility of non-localized (remote) ignition in shock tubes. Furthermore, we show that this same strategy can also effectively eliminate or minimize pressure changes due to combustion heat release, thereby enabling quantitative modeling of the kinetics throughout the combustion event using a simple assumption of specified pressure and enthalpy. We measure temperature and OH radical time-histories during ethylene-oxygen combustion behind reflected shock waves in a constrained reaction volume and verify that the results can be accurately modeled using a detailed mechanism and a specified pressure and enthalpy constraint. © 2013 The Combustion Institute.

  16. Crest lines extraction in volume 3D medical images : a multi-scale approach

    OpenAIRE

    Monga, Olivier; Lengagne, Richard; Deriche, Rachid

    1994-01-01

    Projet SYNTIM; Recently, we have shown that the differential properties of the surfaces represented by 3D volumic images can be recovered using their partial derivatives. For instance, the crest lines can be characterized by the first, second and third partial derivatives of the grey level function $I(x,y,z)$. In this paper, we show that~: - the computation of the partial derivatives of an image can be improved using recursive filters which approximate the Gaussian filter, - a multi-scale app...

  17. Combining Small-Volume Metabolomic and Transcriptomic Approaches for Assessing Brain Chemistry

    OpenAIRE

    Knolhoff, Ann M.; Nautiyal, Katherine M.; Nemes, Peter; Kalachikov, Sergey; Morozova, Irina; Silver, Rae; Jonathan V. Sweedler

    2013-01-01

    The integration of disparate data types provides a more complete picture of complex biological systems. Here we combine small-volume metabolomic and transcriptomic platforms to determine subtle chemical changes and to link metabolites and genes to biochemical pathways. Capillary electrophoresis–mass spectrometry (CE–MS) and whole-genome gene expression arrays, aided by integrative pathway analysis, were utilized to survey metabolomic/transcriptomic hippocampal neurochemistry. We measured chan...

  18. A new MODIS based approach for gas flared volumes estimation: the case of the Val d'Agri Oil Center (Southern Italy)

    Science.gov (United States)

    Lacava, T.; Faruolo, M.; Coviello, I.; Filizzola, C.; Pergola, N.; Tramutoli, V.

    2014-12-01

    Gas flaring is one of the most controversial energetic and environmental issues the Earth is facing, moreover contributing to the global warming and climate change. According to the World Bank, each year about 150 Billion Cubic Meter of gas are being flared globally, that is equivalent to the annual gas use of Italy and France combined. Besides, about 400 million tons of CO2 (representing about 1.2% of global CO2 emissions) are added annually into the atmosphere. Efforts to evaluate the impact of flaring on the surrounding environment are hampered by lack of official information on flare locations and volumes. Suitable satellite based techniques could offers a potential solution to this problem through the detection and subsequent mapping of flare locations as well as gas emissions estimation. In this paper a new methodological approach, based on the Robust Satellite Techniques (RST), a multi-temporal scheme of satellite data analysis, was developed to analyze and characterize the flaring activity of the largest Italian gas and oil pre-treatment plant (ENI-COVA) located in Val d'Agri (Basilicata) For this site, located in an anthropized area characterized by a large environmental complexity, flaring emissions are mainly related to emergency conditions (i.e. waste flaring), being the industrial process regulated by strict regional laws. With reference to the peculiar characteristics of COVA flaring, the RST approach was implemented on 13 years of EOS-MODIS (Earth Observing System - Moderate Resolution Imaging Spectroradiometer) infrared data to detect COVA-related thermal anomalies and to develop a regression model for gas flared volume estimation. The methodological approach, the whole processing chain and the preliminarily achieved results will be shown and discussed in this paper. In addition, the possible implementation of the proposed approach on the data acquired by the SUOMI NPP - VIIRS (National Polar-orbiting Partnership - Visible Infrared Imaging

  19. A new approach to analyzing solar coronal spectra and updated collisional ionization equilibrium calculations. II. Additional recombination rate coefficients

    CERN Document Server

    Bryans, P; Savin, D W

    2008-01-01

    We have reanalyzed SUMER observations of a parcel of coronal gas using new collisional ionization equilibrium (CIE) calculations. These improved CIE fractional abundances were calculated using state-of-the-art electron-ion recombination data for K-shell, L-shell, Na-like, and Mg-like ions of all elements from H through Zn and, additionally, Al- through Ar-like ions of Fe. Improved CIE calculations based on these data are presented here. We have also developed a new systematic method for determining the average emission measure (EM) and electron temperature (T_e) of an emitting plasma. With our new CIE data and our new approach for determining the average EM and T_e we have reanalyzed SUMER observations of the solar corona. We have compared our results with those of previous studies and found some significant differences for the derived EM and T_e. We have also calculated the enhancement of coronal elemental abundances compared to their photospheric abundances, using the SUMER observations themselves to determ...

  20. A facile pollutant-free approach toward a series of nutritionally effective calcium phosphate nanomaterials for food and drink additives

    Science.gov (United States)

    Wang, Jieru; Chen, Xiaoyi; Yang, Xianyan; Xu, Sanzhong; Zhang, Xinli; Gou, Zhongru

    2011-03-01

    Micronutrient malnutrition is widespread and constitutes one of the main nutritional problems worldwide. Vitamins, amino acids, carbohydrates and Ca-phosphate (CaP) minerals are important to human health and disease prevention. Herein we developed a simple wet-chemical method to prepare multinary nutrients-containing CaP nanomaterials in diluted apple, orange, and grape juices. The scanning electron microscopy observation shows that these nanomaterials are short plate-like CaP nanocrystals of 500 nm in length. The X-ray photoelectron spectroscopy, nitrogen adsorption, thermogravimetric analyses confirm the different specific surface area and organic nutrient contents. The Fourier transform infrared and X-ray diffraction analyses indicate there exist similar organic groups (i.e., COO-, HN-CO) but different CaP species in the precipitates. The dissolution test in vitro simulated stomach juice pH condition indicates that these inorganic-organic nanohybrid materials are multidoped by micronutrients (such as Zn, Sr, Mg, K, vitamin c) and can be readily dissolved in the weak acidic aqueous solutions. This highly efficient utilization of fruit juice to produce CaP-based micronutrient composites may minimize the adverse side effect, so that the nanomaterials are promising as functional food/drink additives. Thus, this novel approach is environmentally and biologically friendly to produce edible nutrients while production cost is attained.

  1. Framework and guidelines for implementing the co-management approach: volume I : context, concept and principles

    National Research Council Canada - National Science Library

    1999-01-01

    The purpose of this document is to develop a common understanding of the co-management approach in fisheries management and to provide an overview of the various frameworks used for its implementation...

  2. APPROACH TO ESTIMATION OF THE MARKET VOLUME FOR COMPANIES OPERATING IN THE B2B SEGMENT

    Directory of Open Access Journals (Sweden)

    Alla B. Kochergina

    2014-01-01

    Full Text Available This article shows the approach for estimating amount of alive enterprises inRussia. The main focus is on the way of detecting an business-active companiesusing the formal signs. The author proposes some signs for indicating of thebusiness activity. The developed model allows to clarify the amount of active enterprises in stages using those signs. The author provides the approach how to applythis model for different markets.

  3. Forecasting of exported volume for brazilian fruits by time series analysis: an arima/garch approach

    Directory of Open Access Journals (Sweden)

    Abdinardo Moreira Barreto de Oliveira

    2015-06-01

    Full Text Available The aim of this paper was to offer econometric forecasting models to the Brazilian exported volume fruits, with a view to assisting the planning and production control, also motivated by the existence of a few published papers dealing with this issue. In this sense, it was used the ARIMA/GARCH models, considering, likewise, the occurrence of a multiplicative stochastic seasonality in these series. They were collected 300 observations of exported net weight (kg between Jan/1989 and Dec/2013 of the following fruits: pineapple, banana, orange, lemon, apple, papaya, mango, watermelon, melon and grape, which selection criteria was its importance in the exported basket fruit, because they represented 97% of total received dollars, and 99% of total volume sold in 2010, of a population about 28 kinds of exported fruits. The results showed that it was not only observed the existence of a 12 month multiplicative seasonality in banana and mango. On the other hand, they were identified two fruits groups: (1 those which are continuously exported, and (2 those which have export peaks. On the quality of the models, they were considered satisfactory for six of the ten fruits analyzed. On the volatility, it was seen a high persistence in banana and papaya series, pointing to the existence of a structural break in time series, which could be linked to the economic crises happened in the last 17 years.

  4. Approaching a more Complete Picture of Rockfall Activity: Seismic and LiDAR Detection, Loaction and Volume Estimates

    Science.gov (United States)

    Dietze, Michael; Mohadjer, Solmaz; Turowski, Jens; Ehlers, Todd; Hovius, Niels

    2016-04-01

    Rockfall activity in steep alpine landscapes is often difficult to survey due to its infrequent nature. Classic approaches are limited by temporal and spatial resolution. In contrast, seismic monitoring provides access to catchment-wide analysis of activity patterns in rockfall-dominated environments. The deglaciated U-shaped Lauterbrunnen Valley in the Bernese Oberland, Switzerland, is a perfect example of such landscapes. It was instrumented with up to six broadband seismometers and repeatedly surveyed by terrestrial LiDAR to provide independent validation data. During August-October 2014 and April-June 2015 more than 23 (LiDAR) to hundred (seismic) events were detected. Their volumes range from conditions that control such processes in a comprehensive way. Taken together, the combined LiDAR and seismic monitoring approach provides high fidelity spatial and temporal resolution of individual events.

  5. A finite volume approach for the simulation of nonlinear dissipative acoustic wave propagation

    CERN Document Server

    Velasco-Segura, Roberto

    2013-01-01

    A form of the conservation equations for fluid dynamics is presented, deduced using slightly less restrictive hypothesis than those necessary to obtain the well known Westervelt equation. This formulation accounts for full wave diffraction, nonlinearity, and thermoviscous dissipative effects. A CLAWPACK based, 2D finite volume method using the Roe linearization was implemented to obtain numerically the solution of the proposed equations. In order to validate the code, two different tests have been performed: one against a special Taylor shock-like analytic solution, the other against published results on a HIFU system, both with satisfactory results. The code is based on CLAWPACK and is written for parallel execution on a GPU, thus improving performance by a factor of over 60 when compared to the standard CLAWPACK code.

  6. A finite volume alternate direction implicit approach to modeling selective laser melting

    DEFF Research Database (Denmark)

    Hattel, Jesper Henri; Mohanty, Sankhya

    2013-01-01

    is proposed for modeling single-layer and few-layers selective laser melting processes. The ADI technique is implemented and applied for two cases involving constant material properties and non-linear material behavior. The ADI FV method consume less time while having comparable accuracy with respect to 3D...... to accurately simulate the process, are constrained by either the size or scale of the model domain. A second challenging aspect involves the inclusion of non-linear material behavior into the 3D implicit FE models. An alternating direction implicit (ADI) method based on a finite volume (FV) formulation......Over the last decade, several studies have attempted to develop thermal models for analyzing the selective laser melting process with a vision to predict thermal stresses, microstructures and resulting mechanical properties of manufactured products. While a holistic model addressing all involved...

  7. A multiresolution image based approach for correction of partial volume effects in emission tomography

    Energy Technology Data Exchange (ETDEWEB)

    Boussion, N; Hatt, M; Lamare, F; Bizais, Y; Turzo, A; Rest, C Cheze-Le; Visvikis, D [INSERM U650, Laboratoire du Traitement de l' Information Medicale (LaTIM), CHU Morvan, Brest (France)

    2006-04-07

    Partial volume effects (PVEs) are consequences of the limited spatial resolution in emission tomography. They lead to a loss of signal in tissues of size similar to the point spread function and induce activity spillover between regions. Although PVE can be corrected for by using algorithms that provide the correct radioactivity concentration in a series of regions of interest (ROIs), so far little attention has been given to the possibility of creating improved images as a result of PVE correction. Potential advantages of PVE-corrected images include the ability to accurately delineate functional volumes as well as improving tumour-to-background ratio, resulting in an associated improvement in the analysis of response to therapy studies and diagnostic examinations, respectively. The objective of our study was therefore to develop a methodology for PVE correction not only to enable the accurate recuperation of activity concentrations, but also to generate PVE-corrected images. In the multiresolution analysis that we define here, details of a high-resolution image H (MRI or CT) are extracted, transformed and integrated in a low-resolution image L (PET or SPECT). A discrete wavelet transform of both H and L images is performed by using the 'a trous' algorithm, which allows the spatial frequencies (details, edges, textures) to be obtained easily at a level of resolution common to H and L. A model is then inferred to build the lacking details of L from the high-frequency details in H. The process was successfully tested on synthetic and simulated data, proving the ability to obtain accurately corrected images. Quantitative PVE correction was found to be comparable with a method considered as a reference but limited to ROI analyses. Visual improvement and quantitative correction were also obtained in two examples of clinical images, the first using a combined PET/CT scanner with a lymphoma patient and the second using a FDG brain PET and corresponding T1

  8. Development of a compressive surface capturing formulation for modelling free-surface flow by using the volume-of-fluid approach

    CSIR Research Space (South Africa)

    Heyns, Johan A

    2012-06-01

    Full Text Available combines a blended higher resolution scheme with the addition of an artificial compressive term to the volume-of-fluid equation. This reduces the numerical smearing of the interface associated with explicit higher resolution schemes while limiting...

  9. Talking and Testing: Discourse Approaches to the Assessment of Oral Proficiency. Studies in Bilingualism, Volume 14.

    Science.gov (United States)

    Young, Richard, Ed.; He, Agnes Weiyun, Ed.

    Papers on second language oral proficiency testing include: "Language Proficiency Interviews: A Discourse Approach" (Agnes Weiyun He, Richard Young); "Re-Analyzing the OPI: How Much Does It Look Like Natural Conversation?" (Marysia Johnson, Andrea Tyler); "Evaluating Learner Interactional Skills: Conversation at the Micro Level" (Heidi…

  10. Performed Culture: An Approach to East Asian Language Pedagogy. Pathways to Advanced Skills Series, Volume 11

    Science.gov (United States)

    Christensen, Matthew; Warnick, Paul

    2006-01-01

    This book is a general introduction to the performed culture approach, which trains students how to express themselves in a way that native speakers of the target culture feel appropriate in given situations. Target readership includes Chinese, Japanese, and Korean language teachers and graduate students. Chapters of this book include: (1)…

  11. A novel convolution-based approach to address ionization chamber volume averaging effect in model-based treatment planning systems

    Science.gov (United States)

    Barraclough, Brendan; Li, Jonathan G.; Lebron, Sharon; Fan, Qiyong; Liu, Chihray; Yan, Guanghua

    2015-08-01

    The ionization chamber volume averaging effect is a well-known issue without an elegant solution. The purpose of this study is to propose a novel convolution-based approach to address the volume averaging effect in model-based treatment planning systems (TPSs). Ionization chamber-measured beam profiles can be regarded as the convolution between the detector response function and the implicit real profiles. Existing approaches address the issue by trying to remove the volume averaging effect from the measurement. In contrast, our proposed method imports the measured profiles directly into the TPS and addresses the problem by reoptimizing pertinent parameters of the TPS beam model. In the iterative beam modeling process, the TPS-calculated beam profiles are convolved with the same detector response function. Beam model parameters responsible for the penumbra are optimized to drive the convolved profiles to match the measured profiles. Since the convolved and the measured profiles are subject to identical volume averaging effect, the calculated profiles match the real profiles when the optimization converges. The method was applied to reoptimize a CC13 beam model commissioned with profiles measured with a standard ionization chamber (Scanditronix Wellhofer, Bartlett, TN). The reoptimized beam model was validated by comparing the TPS-calculated profiles with diode-measured profiles. Its performance in intensity-modulated radiation therapy (IMRT) quality assurance (QA) for ten head-and-neck patients was compared with the CC13 beam model and a clinical beam model (manually optimized, clinically proven) using standard Gamma comparisons. The beam profiles calculated with the reoptimized beam model showed excellent agreement with diode measurement at all measured geometries. Performance of the reoptimized beam model was comparable with that of the clinical beam model in IMRT QA. The average passing rates using the reoptimized beam model increased substantially from 92.1% to

  12. Narrow band SWIR hyperspectral imaging: a new approach based on volume Bragg grating

    Science.gov (United States)

    Verhaegen, M.; Lessard, S.; Blais-Ouellette, S.

    2012-06-01

    Volume Bragg grating technology has enabled the development of a new type of staring hyperspectral camera. Based on Bragg Tunable filters, these hyperspectral cameras have both high spectral and spatial resolution, and significantly higher sensitivity than competing technologies like push broom spectrometer, liquid crystal tunable filters, or acousto-optic tunable filters. They are minimally sensitive to polarization and their spectral isolation can reach 106. Here we thus present an innovative tool to collect SWIR hyperspectral data with high spectral and spatial resolution. This new instrument is based on a 3nm bandwidth Bragg Tunable Filter, continuously tunable from 1.0um and 2.5um. Because high spectral resolution also means less light per channel, a low noise custom HgCdTe (MCT) camera was also developed to meet the requirement of the filter. The high speed capability of more than 300 fps and the low operating temperature of 200K (deep cooled option to 77K) allow full frame 500 spectral channel datacube acquisitions in minimal time. Basic principle of this imaging filter will be reviewed as well as the custom MCT camera performances. High resolution hyperspectral measurements will be demonstrated between 1.0um and 2.5um on different objects.

  13. Development of Ethnoscience Approach in The Module Theme Substance Additives to Improve the Cognitive Learning Outcome and Student’s entrepreneurship

    Science.gov (United States)

    Sudarmin; Febu, R.; Nuswowati, M.; Sumarni, W.

    2017-04-01

    Ethnoscience approach is an interesting research today. The purpose of this research is to develop approaches ethnoscience and modules ethnoscience theme additives based ethnoscience; as well as assess the feasibility and effectiveness of module theme additives based ethnoscience to improve learning outcomes and the entrepreneurial character of students. This type of research is the Research and Development (R & D). In this research consist of four stages, namely define, design, development and implementation. The subjects of this study were students of the School of MTs Maarif NU Brebes. Data were analyzed by descriptive qualitative and quantitative. The results showed that ethnoscience approach and the module theme substance additives used declared worthy of National Education Standards Agency (BNSP) with an average percentage of validation on the feasibility aspect of the content, language feasibility, and feasibility of presenting respectively for 94.3%, 86 % and 92% and a very decent entry criteria. The effect of the application modules substance additive based ethnoscience can improve on the cognitive learning classical amounted to 90.63%, and increased learning outcomes category was based on the scores of N-gain. Influence ethnoscience approach application and module theme substances additives based ethnoscience able to improve the entrepreneurial character of students. Based on the results of this study concluded that the ethnoscience approach and module theme substance additives based ethnoscience effective to improve learning outcomes and students’ entrepreneurship.

  14. Choroidal Mapping; a Novel Approach for Evaluating Choroidal Thickness and Volume

    Directory of Open Access Journals (Sweden)

    Jila Noori

    2012-01-01

    Full Text Available There are a limited number of non-invasive imaging techniques available for assessing the choroid, a structure that may be affected by a variety of retinal disorders or become primarily involved in conditions such as polypoidal choroidal vasculopathy and choroidal tumors. The introduction of enhanced depth imaging optical coherence tomography (EDI-OCT has provided the advantage of in vivo cross-sectional imaging of the choroid, similar to the retina, with standard commercially available spectraldomain OCT machines. In this article, we review this imaging technique and introduce choroidal mapping as a novel approach for obtaining accurate topographic and volumetric information on the choroid in normal and diseased states.

  15. 3D modeling of forces between magnet and HTS in a levitation system using new approach of the control volume method based on an unstructured grid

    Energy Technology Data Exchange (ETDEWEB)

    Alloui, L., E-mail: lotfi.alloui@lgep.supelec.fr [Laboratoire de Genie Electrique de Paris - LGEP, CNRS UMR 8507, Supelec, Universite Pierre et Marie Curie-Paris 6, Universite Paris Sud-Paris 11, Plateau de Moulon, 11 rue Joliot Curie, 91192 Gif-Sur-Yvette Cedex (France); Laboratoire de modelisation des systemes energetiques (LMSE), Universite de Biskra, 07000 Biskra (Algeria); Bouillault, F., E-mail: bouillault@lgep.supelec.fr [Laboratoire de Genie Electrique de Paris - LGEP, CNRS UMR 8507, Supelec, Universite Pierre et Marie Curie-Paris 6, Universite Paris Sud-Paris 11, Plateau de Moulon, 11 rue Joliot Curie, 91192 Gif-Sur-Yvette Cedex (France); Bernard, L., E-mail: laurent.bernardl@lgep.supelc.fr [Laboratoire de Genie Electrique de Paris - LGEP, CNRS UMR 8507, Supelec, Universite Pierre et Marie Curie-Paris 6, Universite Paris Sud-Paris 11, Plateau de Moulon, 11 rue Joliot Curie, 91192 Gif-Sur-Yvette Cedex (France); Leveque, J., E-mail: jean.leveque@green.uhp-nancy.fr [Groupe de recherche en electronique et electrotechnique de Nancy, Universite Henry Poincare, BP 239, 54506 Vandoeuvre les Nancy (France)

    2012-05-15

    In this paper we present new 3D numerical model to calculate the vertical and the guidance forces in high temperature superconductors taking into account the influence of the flux creep phenomena. In the suggested numerical model, we adopt a new approach of the control volume method. This approach is based on the use of an unstructured grid which can be used to model more complex geometries. A comparison of the control volume method results with experiments verifies the validity of this approach and the proposed numerical model. Based on this model, the levitation force's relaxation at different temperatures was also studied.

  16. Structured assessment approach version 1. License submittal document content and format for material control and accounting assessment. Volume II

    Energy Technology Data Exchange (ETDEWEB)

    Parziale, A.A.; Sacks, I.J.

    1979-10-01

    A methodology, the Structured Assessment Approach, has been developed for the assessment of the effectiveness of material control and accounting (MC and A) safeguards systems at nuclear fuel cycle facilities. This methodology has been refined into a computational tool, the SAA Version 1 computational package, that was used first to analyze a hypothetical fuel cycle facility and used more recently to assess operational nuclear plants. The Version 1 analysis package is designed to analyze safeguards systems that prevent the diversion of special nuclear material (SNM) from nuclear fuel cycle facilities and to provide assurance that diversion has not occurred. This report is the second volume, the License Submittal Document Content and Format for Material Control and Accounting Assessment, of a four-volume document. It presents the content and format of the LSD necessary for Material Control and Accounting (MC and A) assessment with the SAA Version 1. The LSD is designed to provide the necessary data input to perform all four stages of analyses associated with the SAA. A full-size but Hypothetical Fuel Cycle Facility (HFCF) is used as an example to illustrate the required input data content and data format and to illustrate the procedure for generating the LSD. Generation of the LSD is the responsibility of the nuclear facility licensee applicant.

  17. Human factors evaluation of teletherapy: Identification of problems and alternative approaches. Volume 1

    Energy Technology Data Exchange (ETDEWEB)

    Henriksen, K.; Kaye, R.D.; Jones, R. [Hughes Training, Inc., Falls Church, VA (United States); Morisseau, D.S.; Serig, D.I. [Nuclear Regulatory Commission, Washington, DC (United States). Div. of Systems Technology

    1995-07-01

    A series of human factors evaluations was undertaken to better understand the contributing factors to human error in the teletherapy environment. Teletherapy is a multi-disciplinary methodology for treating cancerous tissue through selective exposure to an external beam of ionizing radiation. The principal sources of radiation are a radioactive isotope, typically cobalt60 (Co-60), or a linear accelerator device capable of producing very high energy x-ray and electron beams. A team of human factors specialists, assisted by a panel of radiation oncologists, medical physicists, and radiation technologists, conducted site visits to radiation oncology departments at community hospitals, university centers, and free-standing clinics. A function and task analysis was initially performed to guide subsequent evaluations in the areas of user-system interfaces, procedures, training and qualifications, and organizational policies and practices. The final phase of the project focused on identification of the most significant human factors problems with respect to safe and effective operation of the teletherapy system and an identification and assessment of alternative approaches for resolving the problems. This report presents the findings of this final phase.

  18. A New Approach to Image-Based Estimation of Food Volume

    Directory of Open Access Journals (Sweden)

    Hamid Hassannejad

    2017-06-01

    Full Text Available A balanced diet is the key to a healthy lifestyle and is crucial for preventing or dealing with many chronic diseases such as diabetes and obesity. Therefore, monitoring diet can be an effective way of improving people’s health. However, manual reporting of food intake has been shown to be inaccurate and often impractical. This paper presents a new approach to food intake quantity estimation using image-based modeling. The modeling method consists of three steps: firstly, a short video of the food is taken by the user’s smartphone. From such a video, six frames are selected based on the pictures’ viewpoints as determined by the smartphone’s orientation sensors. Secondly, the user marks one of the frames to seed an interactive segmentation algorithm. Segmentation is based on a Gaussian Mixture Model alongside the graph-cut algorithm. Finally, a customized image-based modeling algorithm generates a point-cloud to model the food. At the same time, a stochastic object-detection method locates a checkerboard used as size/ground reference. The modeling algorithm is optimized such that the use of six input images still results in an acceptable computation cost. In our evaluation procedure, we achieved an average accuracy of 92 % on a test set that includes images of different kinds of pasta and bread, with an average processing time of about 23 s.

  19. Olefin-maleic-anhydride copolymer based additives: a novel approach for compatibilizing blends of waste polyethylene and crumb rubber.

    Science.gov (United States)

    Tóth, Balázs; Varga, Csilla; Bartha, László

    2015-04-01

    In our work processing conditions and mechanical properties of waste polyethylene (PE)/crumb rubber (CR) blends have been improved by new types of compatibilizing additives synthesized from experimental olefin-maleic-anhydride copolymers at our laboratory. Compatibilizing additives have been introduced into the PE/CR blends in 0.2 wt% while CR concentration has been varied between 10 and 50 wt%. For comparison of the effects commercially available MA-g-PO type compatibilizing additives have also been applied. Tensile and Charpy impact tests of the compression moulded samples have been carried out. Several experimental additives have enhanced properties of the PE/CR blends either from the point of view of tensile or Charpy impact strength while commercial additives have had improving effects only on one of the abovementioned mechanical properties but not for both of them simultaneously. Since good mechanical properties could be achieved by our experimental compatibilizers good adhesion in the waste PE/CR samples have been considered and was proven by SEM graphs either.

  20. Copper-catalyzed aldol-type addition of ketones to aromatic nitriles: a simple approach to enaminone synthesis.

    Science.gov (United States)

    Yu, Xiaoqiang; Wang, Longxiang; Feng, Xiujuan; Bao, Ming; Yamamoto, Yoshinori

    2013-04-11

    An efficient method for the synthesis of enaminones is described. The aldol-type addition of ketones to aromatic nitriles proceeded smoothly in the presence of a simple copper catalyst system (CuI-2,2'-bipyridine-NaO(t)Bu) in N,N-dimethylformamide. Enaminones in satisfactory to excellent yields were produced using this technique.

  1. A data-driven approach for modeling post-fire debris-flow volumes and their uncertainty

    Science.gov (United States)

    Friedel, M.J.

    2011-01-01

    This study demonstrates the novel application of genetic programming to evolve nonlinear post-fire debris-flow volume equations from variables associated with a data-driven conceptual model of the western United States. The search space is constrained using a multi-component objective function that simultaneously minimizes root-mean squared and unit errors for the evolution of fittest equations. An optimization technique is then used to estimate the limits of nonlinear prediction uncertainty associated with the debris-flow equations. In contrast to a published multiple linear regression three-variable equation, linking basin area with slopes greater or equal to 30 percent, burn severity characterized as area burned moderate plus high, and total storm rainfall, the data-driven approach discovers many nonlinear and several dimensionally consistent equations that are unbiased and have less prediction uncertainty. Of the nonlinear equations, the best performance (lowest prediction uncertainty) is achieved when using three variables: average basin slope, total burned area, and total storm rainfall. Further reduction in uncertainty is possible for the nonlinear equations when dimensional consistency is not a priority and by subsequently applying a gradient solver to the fittest solutions. The data-driven modeling approach can be applied to nonlinear multivariate problems in all fields of study. ?? 2011.

  2. The scenario approach for countries considering the addition of oral cholera vaccination in cholera preparedness and control plans.

    Science.gov (United States)

    Deen, Jacqueline; von Seidlein, Lorenz; Luquero, Francisco J; Troeger, Christopher; Reyburn, Rita; Lopez, Anna Lena; Debes, Amanda; Sack, David A

    2016-01-01

    Oral cholera vaccination could be deployed in a diverse range of situations from cholera-endemic areas and locations of humanitarian crises, but no clear consensus exists. The supply of licensed, WHO-prequalified cholera vaccines is not sufficient to meet endemic and epidemic needs worldwide and so prioritisation is needed. We have developed a scenario approach to systematically classify situations in which oral cholera vaccination might be useful. Our scenario approach distinguishes between five types of cholera epidemiology based on experiences from around the world and provides evidence that we hope will spur the development of detailed guidelines on how and where oral cholera vaccines could, and should, be most rationally deployed. Copyright © 2016 Elsevier Ltd. All rights reserved.

  3. Additivity Rule for Electron-Molecule Total Cross Section Calculations at 50-5000 eV: A Geometrical Approach

    Institute of Scientific and Technical Information of China (English)

    SHI De-Heng; SUN Jin-Feng; MA Heng; ZHU Zun-Lue; YANG Xiang-Dong

    2007-01-01

    To quantify the changes of the geometric shielding effect in a molecule as the incident electron energy varies,we present an empirical fraction, which represents the total cross section (TCS) contributions of shielded atoms in a molecule at different energies. Using this empirical fraction, a new formulation of the additivity rule is proposed. Using this new additivity rule, the TCSs for electron scattering by CO2, C2H2, C6H12 (cyclo-hexane) and CsH16 (cyclo-octane) are calculated in the range 50-5000 eV. Here the atomic cross sections are derived from the experimental TCS results of simple molecules (H2, O2, CO). The quantitative TCSs are compared with those obtained by experiments and other theories, and good agreement is attained over a wide energy range.

  4. An LMI Approach to H∞ Performance Analysis of Continous-Time System with Two Additive Time-Varying Delays

    Directory of Open Access Journals (Sweden)

    Wrastawa Ridwan

    2011-08-01

    Full Text Available This paper investigates the problem of H∞ performance analysis for continous–time systems with two additive time-varying delays in the state. Our objective is focused on stability analysis of a continuous system with two time-varying delays with an H∞ disturbance attenuation level γ. By exploiting Lyapunov-Krasovski functional and introducing free weighting matrix variables, LMI stability condition have been derived.

  5. Perspectives on Additive Manufacturing

    Science.gov (United States)

    Bourell, David L.

    2016-07-01

    Additive manufacturing (AM) has skyrocketed in visibility commercially and in the public sector. This article describes the development of this field from early layered manufacturing approaches of photosculpture, topography, and material deposition. Certain precursors to modern AM processes are also briefly described. The growth of the field over the last 30 years is presented. Included is the standard delineation of AM technologies into seven broad categories. The economics of AM part generation is considered, and the impacts of the economics on application sectors are described. On the basis of current trends, the future outlook will include a convergence of AM fabricators, mass-produced AM fabricators, enabling of topology optimization designs, and specialization in the AM legal arena. Long-term developments with huge impact are organ printing and volume-based printing.

  6. Combination of bone morphogenetic protein-2 plasmid DNA with chemokine CXCL12 creates an additive effect on bone formation onset and volume

    NARCIS (Netherlands)

    Wegman, F.; Poldervaart, M. T.; van der Helm, Y. J.; Oner, F. C.; Dhert, W. J.; Alblas, J.

    2015-01-01

    Bone morphogenetic protein-2 (BMP-2) gene delivery has shown to induce bone formation in vivo in cell-based tissue engineering. In addition, the chemoattractant stromal cell-derived factor-1α (SDF-1α, also known as CXCL12) is known to recruit multipotent stromal cells towards its release site where

  7. Instruction of Keyboarding Skills: A Whole Language Approach to Teaching Functional Literacy Skills to Students Who are Blind and Have Additional Disabilities

    Science.gov (United States)

    Stauffer, Mary

    2008-01-01

    This article describes an unconventional method to teach un-contracted braille reading and writing skills to students who are blind and have additional disabilities. It includes a keyboarding curriculum that focuses on the whole language approach to literacy. A special feature is the keyboard that is adapted with braille symbols. Un-contracted…

  8. Degradation of magenta dye using different approaches based on ultrasonic and ultraviolet irradiations: Comparison of effectiveness and effect of additives for intensification.

    Science.gov (United States)

    Karnjkar, Yogesh S; Dinde, Raveena M; Dinde, Nikita M; Bawankar, Kanchan N; Hinge, Shruti P; Mohod, Ashish V; Gogate, Parag R

    2015-11-01

    The conventional chemical oxidation methods have not been very successful for the treatment of dyes due to higher stability against the oxidizing agents. The present work investigates the application of an improved treatment approach based on the ultrasonic and ultraviolet irradiations for treatment of dye containing wastewaters. Magenta dye, which is commonly used in textile industries, has been used as a model compound. Initially, the experiments have been performed using individual operation of ultrasonic and ultraviolet irradiations. Studies related to effect of concentration revealed that the extent of degradation increased with an increase in the concentration of dye solution till an optimum loading. Intensification of the extent of degradation using ultrasonic irradiation has been investigated using different additives such as NaCl, TiO2, air and starch. Also the efficacy of combined treatment approaches based on different approaches involving ultrasound, ultraviolet irradiation and additives for the removal of magenta dye from the aqueous solution have been evaluated. For the use of additives, maximum intensification was achieved for TiO2 followed by use of NaCl and least effect was observed for starch. For the combined treatment approaches, the maximum extent of degradation (98.8%) and maximum COD removal (94.0%) has been obtained for the combination of ultrasound with 1 g/L TiO2 and air. The present work has clearly demonstrated the efficacy of combined treatment approaches for removal of dyes from the wastewater.

  9. Special report. Upgrading security: hospitals opt for new equipment; new approaches; heavy investments in additional patient, employee protection.

    Science.gov (United States)

    1994-07-01

    An increasing number of hospitals are taking steps to prevent the violence that plagues both urban and rural areas from spilling over into their emergency rooms and nursing units. Four facilities--Duke Medical University Center, Durham, NC; Children's Hospital, Columbus, OH; Ingalls Hospital, Harvey, IL; and University Medical Center, Las Vegas, NV--have recently installed new equipment or implemented innovative security procedures in an effort to better protect patients and employees. Although the price tag for additional protection is often high, officials at the hospitals agree that providing a safe environment is worth the investment.

  10. Additive manufacturing of ITER first wall panel parts by two approaches: Selective laser melting and electron beam melting

    Energy Technology Data Exchange (ETDEWEB)

    Zhong, Yuan [Department of Materials and Environmental Chemistry, Arrhenius Laboratory, Stockholm University, SE-106 91 Stockholm (Sweden); Rännar, Lars-Erik [Department of Quality Technology, Mechanical Engineering and Mathematics, Sports Tech Research Centre, Mid Sweden University, SE-831 25 Östersund (Sweden); Wikman, Stefan [Fusion for Energy, Torres Diagonal Litoral B3, Josep Pla 2, 08019 Barcelona (Spain); Koptyug, Andrey [Department of Quality Technology, Mechanical Engineering and Mathematics, Sports Tech Research Centre, Mid Sweden University, SE-831 25 Östersund (Sweden); Liu, Leifeng; Cui, Daqing [Department of Materials and Environmental Chemistry, Arrhenius Laboratory, Stockholm University, SE-106 91 Stockholm (Sweden); Shen, Zhijian, E-mail: shen@mmk.su.se [Department of Materials and Environmental Chemistry, Arrhenius Laboratory, Stockholm University, SE-106 91 Stockholm (Sweden)

    2017-03-15

    Highlights: • A novel way using additive manufacturing to fabricated ITER First Wall Panel parts is proposed. • ITER First Wall Panel parts successfully manufactured by both SLM and EBM are compared. • Physical and mechanical properties of SLM and EBM SS316L are clearly compared. • Problems encountered for large scale part building were discussed and possible solutions are given. - Abstract: Fabrication of ITER First Wall (FW) Panel parts by two additive manufacturing (AM) technologies, selective laser melting (SLM) and electron beam melting (EBM), was supported by Fusion for Energy (F4E). For the first time, AM is applied to manufacture ITER In-Vessel parts with complex design. Fully dense SS316L was prepared by both SLM and EBM after developing optimized laser/electron beam parameters. Characterizations on the density, magnetic permeability, microstructure, defects and inclusions were carried out. Tensile properties, Charpy-impact properties and fatigue properties of SLM and EBM SS316L were also compared. ITER FW Panel parts were successfully fabricated by both SLM and EBM in a one-step building process. The SLM part has smoother surface, better size accuracy while the EBM part takes much less time to build. Issues with removing support structures might be solved by slightly changing the design of the internal cooling system. Further investigation of the influence of neutron irradiation on materials properties between the two AM technologies is needed.

  11. Microbial oils as food additives: recent approaches for improving microbial oil production and its polyunsaturated fatty acid content.

    Science.gov (United States)

    Bellou, Stamatia; Triantaphyllidou, Irene-Eva; Aggeli, Dimitra; Elazzazy, Ahmed Mohammed; Baeshen, Mohammed Nabih; Aggelis, George

    2016-02-01

    In this short review, we summarize the latest research in the production of polyunsaturated microbial oils that are of interest in food technology. The current research targets the productivity of oleaginous microorganisms, as well as the biosynthesis of particular polyunsaturated fatty acids (PUFAs). The most important efforts target the efficiency of the oleaginous machinery, via overexpression of key-enzymes involved in lipid biosynthesis, as well as the minimization of lipid degradation, by repressing genes involved in the β-oxidation pathway. The production of specific PUFAs is approached by homologous or heterologous expression of specific desaturases and elongases involved in PUFA biosynthesis in oleaginous microorganisms. New perspectives, such as the production of triacylglycerols of specific structure and the employment of adaptive experimental evolution for creating robust oleaginous strains able to produce PUFAs are also discussed.

  12. Final EIS for the Proposed Homeporting of Additional Surface Ships at Naval Station, Mayport, FL. Volume 1. Final Environmental Impact Statement

    Science.gov (United States)

    2008-11-21

    and the native population’s transition from nomadic, big game subsistence/settlement patterns to a more sedentary lifestyle residing along the...Dental Clinic, Chapel, Child Development Center, and NAVSTA Mayport Family Housing. Final EIS for the Proposed Homeporting of Additional Surface Ships...for the more coastal lifestyle (Brockington & Associates 1998, Hardy Heck Moore Inc. 2001). The Late Archaic sub-period underwent another climate

  13. Identifying food proteins with allergenic potential: evolution of approaches to safety assessment and research to provide additional tools.

    Science.gov (United States)

    Ladics, Gregory S; Selgrade, MaryJane K

    2009-08-01

    A safety assessment process exists for genetically engineered crops that includes the evaluation of the expressed protein for allergenic potential. The objectives of this evaluation are twofold: (1) to protect allergic consumers from exposure to known allergenic or cross-reactive proteins, and (2) protect the general population from risks associated with the introduction of genes encoding proteins that are likely to become food allergens. The first systematic approach to address these concerns was formulated by Metcalfe et al. [Metcalfe, D.D., Astwood, J.D., Townsend, R., Sampson, H.A., Taylor, S.L., and Fuchs, R.L. 1996. Assessment of the allergenic potential of foods from genetically engineered crop plants. Crit. Rev. Food Sci. Nutr. 36(5), 165-186.] and subsequently Food and Agriculture Organization of the United Nations/World Health Organization (FAO/WHO) [FAO/WHO, 2001. Evaluation of allergenicity of genetically modified foods. Report of a Joint FAO/WHO Expert Consultation on Allergenicity of Foods Derived from Biotechnology. January 22-25, 2001. Rome, Italy]. More recently, Codex [Codex Alimentarius Commission, 2003. Alinorm 03/34: Joint FAO/WHO Food Standard Programme, Codex Alimentarius Commission, Twenty-Fifth Session, Rome, Italy, 30 June-5 July, 2003. Appendix III, Guideline for the conduct of food safety assessment of foods derived from recombinant-DNA plants, and Appendix IV, Annex on the assessment of possible allergenicity. pp. 47-60], noting that no single factor is recognized as an identifier for protein allergenicity, suggested a weight of evidence approach be conducted that takes into account a variety of factors and approaches for an overall assessment of allergenic potential. These various recommendations are based on what is known about allergens, including the history of exposure and safety of the gene(s) source; amino acid sequence identity to human allergens; stability to pepsin digestion in vitro; protein abundance in the crop and

  14. Food additives data book

    National Research Council Canada - National Science Library

    Smith, Jim; Hong-Shum, Lily

    2011-01-01

    .... Compiled by food industry experts with a proven track record of producing high quality reference work, this volume is the definitive resource for technologists using food additives"-- "The use...

  15. A numerical-statistical approach to determining the representative elementary volume (REV of cement paste for measuring diffusivity

    Directory of Open Access Journals (Sweden)

    Zhang, M. Z.

    2010-12-01

    Full Text Available Concrete diffusivity is a function of its microstructure on many scales, ranging from nanometres to millimetres. Multi-scale techniques are therefore needed to model this parameter. Representative elementary volume (REV, in conjunction with the homogenization principle, is one of the most common multi-scale approaches. This study aimed to establish a procedure for establishing the REV required to determine cement paste diffusivity based on a three-step, numerical-statistical approach. First, several series of 3D cement paste microstructures were generated with HYMOSTRUC3D, a cement hydration and microstructure model, for different volumes of cement paste and w/c ratios ranging from 0.30 to 0.60. Second, the finite element method was used to simulate the diffusion of tritiated water through these microstructures. Effective cement paste diffusivity values for different REVs were obtained by applying Fick’s law. Finally, statistical analysis was used to find the fluctuation in effective diffusivity with cement paste volume, from which the REV was then determined. The conclusion drawn was that the REV for measuring diffusivity in cement paste is 100x100x100 μm3.

    La difusividad del hormigón depende de su microestructura a numerosas escalas, desde nanómetros hasta milímetros, por lo que se precisa de técnicas multiescala para representar este parámetro. Junto con el principio de homogeneización, uno de los métodos multiescala más habituales es el volumen elemental representativo (VER. El objeto de este estudio era establecer un procedimiento que permitiera determinar el VER necesario para calcular la difusividad de la pasta de cemento, basándose en un método numéricoestadístico que consta de tres etapas. Primero, se crearon varias series de microestructuras de pasta de cemento en 3D con HYMOSTRUC3D, un programa que permite crear un modelo de la hidratación y microestructura del cemento. Luego se empleó el método de

  16. Reappraisal of the geothermal potential at Colli Albani volcano (Italy): a new approach to the volume method

    Science.gov (United States)

    Giordano, G.; De Benedetti, A. A.; Ramazzotti, P.; Bonamico, A.; Mattei, M.

    2012-04-01

    High enthalpy geothermal reservoirs are usually associated with fractured rocks. Secondary permeability is however difficult to be predicted thus making it difficult to locate the most productive volumes of the reservoirs. The calculation of the energetic potential in geothermal areas suffers of the large uncertainties associated with secondary permeability issues, facing the task of the interplay between stratification and fracturing on the anisotropic distribution of secondary permeability. The object of this work is the research and informatization of available data for the Colli Albani (Latium, Central Italy) geothermal system, in order to propose a qualitative approach and quantitative identification and description of geothermal systems, applied to the Colli Albani area as a case history. The identification of the rock volumes most promising in terms of industrial exploitation needs the definition of an evaluation matrix. The considered data can be placed in a three dimensional matrix with A axis that accounts for the modeling of the depth of the top of the reservoirs based on geophysical and direct data, and a B axis that accounts for the thermal modeling of the crust (i.e. T with depth) based on measured thermal gradients. Both A and B data are strongly influenced by the geological model therefore, as for the case of Colli Albani, there is certainly a lot of scope into revising existing geological reconstructions of the reservoirs in Central Italy and accordingly reconsidering the interpolation and modeling of both thermal and geophysical data. For the scope of this work, we have taken into account the maps descriptive the thermal structure and the deep distribution of the top of the geothermal reservoirs produced by ENEL and AGIP between the 1970s and 1990s for Cental Italy, and we have detailed the internal structure of the substrate, considering more recent direct and indirect data on the nature of the substratum. Finally, we discuss the implementation

  17. Numerical Simulation of Particle Mixing in Dispersed Gas-Liquid-Solid Flows using a Combined Volume of Fluid and Discrete Particle Approach

    NARCIS (Netherlands)

    Deen, Niels G.; Sint Annaland, van Martin; Kuipers, J.A.M.

    2007-01-01

    In this paper a hybrid model is presented for the numerical simulation of gas-liquid-solid flows using a combined Volume Of Fluid (VOF) and Discrete Particle (DP) approach applied for respectively dispersed gas bubbles and solid particles present in the continuous liquid phase. The hard sphere DP mo

  18. Direct numerical simulation of particle mixing in dispersed gas-liquid-solid flows using a combined volume of fluid and discrete particle approach

    NARCIS (Netherlands)

    Deen, Niels G.; Sint Annaland, van Martin; Kuipers, J.A.M.

    2006-01-01

    In this paper a hybrid model is presented for the numerical simulation of gas-liquid-solid flows using a combined Volume Of Fluid (VOF) and Discrete Particle (DP) approach applied for respectively dispersed gas bubbles and solid particles present in the continuous liquid phase. The hard sphere DP mo

  19. Random Forests approach for identifying additive and epistatic single nucleotide polymorphisms associated with residual feed intake in dairy cattle.

    Science.gov (United States)

    Yao, C; Spurlock, D M; Armentano, L E; Page, C D; VandeHaar, M J; Bickhart, D M; Weigel, K A

    2013-10-01

    ancestor-descendant SNP pairs can be explored as possible epistatic effects for further study. The importance scores generated by RF can be used effectively to identify large additive or epistatic SNP and informative QTL. The consistency in results of our study and previous studies in beef cattle indicates that the genetic architecture of RFI in dairy cattle might be similar to that of beef cattle. Copyright © 2013 American Dairy Science Association. Published by Elsevier Inc. All rights reserved.

  20. Phase diagram of mixtures of hard colloidal spheres and discs: A free-volume scaled-particle approach

    NARCIS (Netherlands)

    Lekkerkerker, H.N.W.; Oversteegen, S.M.

    2004-01-01

    Phase diagrams of mixtures of colloidal hard spheres with hard discs are calculated by means of the free-volume theory. The free-volume fraction available to the discs is determined from scaled-particle theory. The calculations show that depletion induced phase separation should occur at low disc co

  1. Phase diagram of mixtures of hard colloidal spheres and discs: A free-volume scaled-particle approach

    NARCIS (Netherlands)

    Lekkerkerker, H.N.W.; Oversteegen, S.M.

    2004-01-01

    Phase diagrams of mixtures of colloidal hard spheres with hard discs are calculated by means of the free-volume theory. The free-volume fraction available to the discs is determined from scaled-particle theory. The calculations show that depletion induced phase separation should occur at low disc

  2. An integrated approach to seismic event location: 1. Evaluating how method of location affects the volume of groups of hypocenters

    Science.gov (United States)

    Frohlich, Clifford A.

    1992-11-01

    When seismic events occur in spatially compact clusters, the volume and geometric characteristics of these clusters often provides information about the relative effectiveness of different location methods, or about physical processes occurring within the hypocentral region. This report defines and explains how to determine the convex polyhedron of minimum volume (CPMV) surrounding a set of points. We evaluate both single-event and joint hypocenter determination (JHD) relocations for three rather different clusters of seismic events: (1) nuclear explosions from Muroroa relocated using P and PKP phases reported by the ISC; (2) intermediate depth earthquakes near Bucaramanga, Colombia, relocated using P and PKP phases reported by the ISC; and (3) shallow earthquakes near Vanuatu (formerly, the New Hebrides), relocated using P and S phases from a local station network. This analysis demonstrates that different location methods markedly affect the volume of the CPMV, however, volumes for JHD relations are not always smaller than volumes for single-event relocations.

  3. Numerical modelling in building thermo-aeraulics: from CFD modelling to an hybrid finite volume / zonal approach; Modelisation numerique de la thermoaeraulique du batiment: des modeles CFD a une approche hybride volumes finis / zonale

    Energy Technology Data Exchange (ETDEWEB)

    Bellivier, A.

    2004-05-15

    For 3D modelling of thermo-aeraulics in building using field codes, it is necessary to reduce the computing time in order to model increasingly larger volumes. The solution suggested in this study is to couple two modelling: a zonal approach and a CFD approach. The first part of the work that was carried out is the setting of a simplified CFD modelling. We propose rules for use of coarse grids, a constant effective viscosity law and adapted coefficients for heat exchange in the framework of building thermo-aeraulics. The second part of this work concerns the creation of fluid Macro-Elements and their coupling with a calculation of CFD finite volume type. Depending on the boundary conditions of the problem, a local description of the driving flow is proposed via the installation and use of semi-empirical evolution laws. The Macro-Elements is then inserted in CFD computation: the values of velocity calculated by the evolution laws are imposed on the CFD cells corresponding to the Macro-Element. We use these two approaches on five cases representative of thermo-aeraulics in buildings. The results are compared with experimental data and with traditional RANS simulations. We highlight the significant gain of time that our approach allows while preserving a good quality of numerical results. (author)

  4. A novel geotechnical/geostatistical approach for exploration and production of natural gas from multiple geologic strata, Phase 1. Volume 2, Geology and engineering

    Energy Technology Data Exchange (ETDEWEB)

    Overbey, W.K. Jr.; Reeves, T.K.; Salamy, S.P.; Locke, C.D.; Johnson, H.R.; Brunk, R.; Hawkins, L. [BDM Engineering Services Co., Morgantown, WV (United States)

    1991-05-01

    This research program has been designed to develop and verify a unique geostatistical approach for finding natural gas resources. The project has been conducted by Beckley College, Inc., and BDM Engineering Services Company (BDMESC) under contract to the US Department of Energy (DOE), Morgantown Energy Technology Center (METC). This section, Volume II, contains a detailed discussion of the methodology used and the geological and production information collected and analyzed for this study. A companion document, Volume 1, provides an overview of the program, technique and results of the study. In combination, Volumes I and II cover the completion of the research undertaken under Phase I of this DOE project, which included the identification of five high-potential sites for natural gas production on the Eccles Quadrangle, Raleigh County, West Virginia. Each of these sites was selected for its excellent potential for gas production from both relatively shallow coalbeds and the deeper, conventional reservoir formations.

  5. A novel geotechnical/geostatistical approach for exploration and production of natural gas from multiple geologic strata, Phase 1. Volume 2, Geology and engineering

    Energy Technology Data Exchange (ETDEWEB)

    Overbey, W.K. Jr.; Reeves, T.K.; Salamy, S.P.; Locke, C.D.; Johnson, H.R.; Brunk, R.; Hawkins, L. [BDM Engineering Services Co., Morgantown, WV (United States)

    1991-05-01

    This research program has been designed to develop and verify a unique geostatistical approach for finding natural gas resources. The project has been conducted by Beckley College, Inc., and BDM Engineering Services Company (BDMESC) under contract to the US Department of Energy (DOE), Morgantown Energy Technology Center (METC). This section, Volume II, contains a detailed discussion of the methodology used and the geological and production information collected and analyzed for this study. A companion document, Volume 1, provides an overview of the program, technique and results of the study. In combination, Volumes I and II cover the completion of the research undertaken under Phase I of this DOE project, which included the identification of five high-potential sites for natural gas production on the Eccles Quadrangle, Raleigh County, West Virginia. Each of these sites was selected for its excellent potential for gas production from both relatively shallow coalbeds and the deeper, conventional reservoir formations.

  6. ADME evaluation in drug discovery. 2. Prediction of partition coefficient by atom-additive approach based on atom-weighted solvent accessible surface areas.

    Science.gov (United States)

    Hou, T J; Xu, X J

    2003-01-01

    A novel method for the calculations of 1-octanol/water partition coefficient (log P) of organic molecules has been presented here. The method, SLOGP v1.0, estimates the log P values by summing the contribution of atom-weighted solvent accessible surface areas (SASA) and correction factors. Altogether 100 atom/group types were used to classify atoms with different chemical environments, and two correlation factors were used to consider the intermolecular hydrophobic interactions and intramolecular hydrogen bonds. Coefficient values for 100 atom/group and two correction factors have been derived from a training set of 1850 compounds. The parametrization procedure for different kinds of atoms was performed as follows: first, the atoms in a molecule were defined to different atom/group types based on SMARTS language, and the correction factors were determined by substructure searching; then, SASA for each atom/group type was calculated and added; finally, multivariate linear regression analysis was applied to optimize the hydrophobic parameters for different atom/group types and correction factors in order to reproduce the experimental log P. The correlation based on the training set gives a model with the correlation coefficient (r) of 0.988, the standard deviation (SD) of 0.368 log units, and the absolute unsigned mean error of 0.261. Comparison of various procedures of log P calculations for the external test set of 138 organic compounds demonstrates that our method bears very good accuracy and is comparable or even better than the fragment-based approaches. Moreover, the atom-additive approach based on SASA was compared with the simple atom-additive approach based on the number of atoms. The calculated results show that the atom-additive approach based on SASA gives better predictions than the simple atom-additive one. Due to the connection between the molecular conformation and the molecular surface areas, the atom-additive model based on SASA may be a more

  7. Phase diagram of mixtures of hard colloidal spheres and discs: A free-volume scaled-particle approach

    OpenAIRE

    Lekkerkerker, H. N. W.; Oversteegen, S.M.

    2004-01-01

    Phase diagrams of mixtures of colloidal hard spheres with hard discs are calculated by means of the free-volume theory. The free-volume fraction available to the discs is determined from scaled-particle theory. The calculations show that depletion induced phase separation should occur at low disc concentrations in systems now experimentally available. The gas–liquid equilibrium of the spheres becomes stable at comparable size ratios as with bimodal mixtures of spheres or mixtures of rods and ...

  8. Implementation of image-guided brachytherapy (IGBT) for patients with uterine cervix cancer: a tumor volume kinetics approach

    Science.gov (United States)

    Mendez, Lucas Castro; Stuart, Silvia Radwanski; Guimarães, Roger Guilherme Rodrigues; Ramos, Clarissa Cerchi Angotti; de Paula, Lucas Assad; de Sales, Camila Pessoa; Chen, André Tsin Chih; Blasbalg, Roberto; Baroni, Ronaldo Hueb

    2016-01-01

    Purpose To evaluate tumor shrinking kinetics in order to implement image-guided brachytherapy (IGBT) for the treatment of patients with cervix cancer. Material and methods This study has prospectively evaluated tumor shrinking kinetics of thirteen patients with uterine cervix cancer treated with combined chemoradiation. Four high dose rate brachytherapy fractions were delivered during the course of pelvic external beam radiation therapy (EBRT). Magnetic resonance imaging (MRI) exams were acquired at diagnosis (D), first (B1), and third (B3) brachytherapy fractions. Target volumes (GTV and HR-CTV) were calculated by both the ellipsoid formula (VE) and MRI contouring (VC), which were defined by a consensus between at least two radiation oncologists and a pelvic expert radiologist. Results Most enrolled patients had squamous cell carcinoma and FIGO stage IIB disease, and initiated brachytherapy after the third week of pelvic external beam radiation. Gross tumor volume volume reduction from diagnostic MRI to B1 represented 61.9% and 75.2% of the initial volume, when measured by VE and VC, respectively. Only a modest volume reduction (15-20%) was observed from B1 to B3. Conclusions The most expressive tumor shrinking occurred in the first three weeks of oncological treatment and was in accordance with gynecological examination. These findings may help in IGBT implementation. PMID:27648083

  9. A New, Effective and Low-Cost Three-Dimensional Approach for the Estimation of Upper-Limb Volume

    Directory of Open Access Journals (Sweden)

    Roberto Buffa

    2015-05-01

    Full Text Available The aim of this research was to validate a new procedure (SkanLab for the three-dimensional estimation of total arm volume. SkanLab is based on a single structured-light Kinect sensor (Microsoft, Redmond, WA, USA and on Skanect (Occipital, San Francisco, CA, USA and MeshLab (Visual Computing Lab, Pisa, Italy software. The volume of twelve plastic cylinders was measured using geometry, as the reference, water displacement and SkanLab techniques (two raters and repetitions. The right total arm volume of thirty adults was measured by water displacement (reference and SkanLab (two raters and repetitions. The bias and limits of agreement (LOA between techniques were determined using the Bland–Altman method. Intra- and inter-rater reliability was assessed using the intraclass correlation coefficient (ICC and the standard error of measurement. The bias of SkanLab in measuring the cylinders volume was −21.9 mL (−5.7% (LOA: −62.0 to 18.2 mL; −18.1% to 6.7% and in measuring the volume of arms’ was −9.9 mL (−0.6% (LOA: −49.6 to 29.8 mL; −2.6% to 1.4%. SkanLab’s intra- and inter-rater reliabilities were very high (ICC >0.99. In conclusion, SkanLab is a fast, safe and low-cost method for assessing total arm volume, with high levels of accuracy and reliability. SkanLab represents a promising tool in clinical applications.

  10. Phase diagram of mixtures of hard colloidal spheres and discs: a free-volume scaled-particle approach.

    Science.gov (United States)

    Oversteegen, S M; Lekkerkerker, H N W

    2004-02-01

    Phase diagrams of mixtures of colloidal hard spheres with hard discs are calculated by means of the free-volume theory. The free-volume fraction available to the discs is determined from scaled-particle theory. The calculations show that depletion induced phase separation should occur at low disc concentrations in systems now experimentally available. The gas-liquid equilibrium of the spheres becomes stable at comparable size ratios as with bimodal mixtures of spheres or mixtures of rods and spheres. Introducing finite thickness of the platelets gives rise to a significant lowering of the fluid branch of the binodal. Copyright 2004 American Institute of Physics

  11. Effects of approach and injection volume on diffusion of mepivacaine hydrochloride during local analgesia of the deep branch of the lateral plantar nerve in horses.

    Science.gov (United States)

    Claunch, Kevin M; Eggleston, Randy B; Baxter, Gary M

    2014-11-15

    To compare the effects of 2 approaches and 2 injection volumes on diffusion of mepivacaine hydrochloride for local analgesia of the deep branch of the lateral plantar nerve (DBLPN) in horses. Experimental study. 16 adult horses. Either 2 mL (low volume) or 8 mL (high volume) of mepivacaine hydrochloride-iohexol (50:50 mixture) was injected by means of 1 of 2 techniques to produce analgesia of the DBLPN. For technique 1, the needle was inserted 15 mm distal to the head of the fourth metatarsal bone and directed perpendicular to the limb. For technique 2, the needle was inserted 20 mm distal to the head of the fourth metatarsal bone and was directed in a proximodorsal direction. Lateromedial radiographs were obtained before and 5, 15, 30, and 60 minutes after injection. Radiographs were evaluated to determine the proximal and distal extent of diffusion of the contrast solution and presumably anesthetic agent and whether contrast agent appeared to be present in the tarsal sheath or tarsometatarsal joint. A high degree of variability in contrast solution diffusion was noted among injections. High-volume injections diffused significantly further proximally and distally than did low-volume injections. Contrast agent was documented within the tarsal sheath in 5 of 32 (16%) injections and within the tarsometatarsal joint in 2 of 32 (6%) injections. No significant difference was found for risk of inadvertent tarsal sheath or tarsometatarsal joint injection between the 2 techniques or the 2 volumes of anesthetic used. Mepivacaine diffused significantly further distally with technique 1 than with technique 2 but diffused significantly further proximally with technique 2 than with technique 1. For both techniques, diffusion in the distal but not the proximal direction significantly increased over time. Results indicated that the proximal and distal diffusion of the mepivacaine-iohexol solution was quite variable following either DBLPN nerve block technique.

  12. Lesson Plans for the Busy Librarian: A Standards Based Approach for the Elementary Library Media Center, Volume 2

    Science.gov (United States)

    Keeling, Joyce

    2005-01-01

    The author designed this book, like Volume I of the set, to give elementary school librarians a quick, enjoyable way to coordinate with teachers to teach information literacy and literacy skills aligned with national standards. The chapters in the book include: (1) Kindergarten Lesson Plans; (2) First-Grade Lesson Plans; (3) Second-Grade Lesson…

  13. A principal component approach for predicting the stem volume in Eucalyptus plantations in Brazil using airborne LiDAR data

    Science.gov (United States)

    Carlos Alberto Silva; Carine Klauberg; Andrew T. Hudak; Lee A. Vierling; Veraldo Liesenberg; Samuel P. C. e Carvalho; Luiz C. E. Rodriguez

    2016-01-01

    Improving management practices in industrial forest plantations may increase production efficiencies, thereby reducing pressures on native tropical forests for meeting global pulp needs. This study aims to predict stem volume (V) in plantations of fast-growing Eucalyptus hybrid clones located in southeast Brazil using field plot and airborne Light Detection...

  14. Volume overload cleanup: An approach for on-line SPE-GC, GPC-GC, and GPC-SPE-GC

    NARCIS (Netherlands)

    Kerkdijk, H.; Mol, H.G.J.; Nagel, B. van der

    2007-01-01

    A new concept for cleanup, based on volume overloading of the cleanup column, has been developed for on-line coupling of gel permeation chromatography (GPC), solid-phase extraction (SPE), or both, to gas chromatography (GC). The principle is outlined and the applicability demonstrated by the determi

  15. Efficient embryo transfer in the common marmoset monkey (Callithrix jacchus) with a reduced transfer volume: a non-surgical approach with cryopreserved late-stage embryos.

    Science.gov (United States)

    Ishibashi, Hidetoshi; Motohashi, Hideyuki H; Kumon, Mami; Yamamoto, Kazuhiro; Okada, Hironori; Okada, Takashi; Seki, Kazuhiko

    2013-05-01

    Among primates, the common marmoset is suitable for primate embryology research. Its small body size, however, has delayed the technical development of efficient embryo transfer. Furthermore, three factors have been determined to adversely affect the performance of marmoset embryo transfer: nonsurgical approaches, the use of cryopreserved embryos, and the use of late-stage embryos. Here we performed embryo transfer under conditions that included the above three factors and using either a small (1 μl or less) or a large volume (2-3 μl) of medium. The pregnancy and birth rates were 50% (5/10) and 27% (3/11), respectively, when using the large volume, and 80% (8/10) and 75% (9/12), respectively, when using the small volume. The latter scores exceed those of previous reports using comparable conditions. Thus, it appears that these three previously considered factors could be overcome, and we propose that reducing the transfer volume to 1 μl or less is essential for successful marmoset embryo transfer.

  16. Improving clinical outcomes among hemodialysis patients: a proposal for a "volume first" approach from the chief medical officers of US dialysis providers.

    Science.gov (United States)

    Weiner, Daniel E; Brunelli, Steven M; Hunt, Abigail; Schiller, Brigitte; Glassock, Richard; Maddux, Frank W; Johnson, Douglas; Parker, Tom; Nissenson, Allen

    2014-11-01

    Addressing fluid intake and volume control requires alignment and coordination of patients, providers, dialysis facilities, and payers, potentially necessitating a "Volume First" approach. This article reports the consensus opinions achieved at the March 2013 symposium of the Chief Medical Officers of 14 of the largest dialysis providers in the United States. These opinions are based on broad experience among participants, but often reinforced by only observational and frequently retrospective studies, highlighting the lack of high-quality clinical trials in nephrology. Given the high morbidity and mortality rates among dialysis patients and the absence of sufficient trial data to guide most aspects of hemodialysis therapy, participants believed that immediate attempts to improve care based on quality improvement initiatives, physiologic principles, and clinical experiences are warranted until such time as rigorous clinical trial data become available. The following overarching consensus opinions emerged. (1) Extracellular fluid status should be a component of sufficient dialysis, such that approaching normalization of extracellular fluid volume should be a primary goal of dialysis care. (2) Fluid removal should be gradual and dialysis treatment duration should not routinely be less than 4 hours without justification based on individual patient factors. (3) Intradialytic sodium loading should be avoided by incorporating dialysate sodium concentrations set routinely in the range of 134-138 mEq/L, avoidance of routine use of sodium modeling, and avoidance of hypertonic saline solution. (4) Dietary counseling should emphasize sodium avoidance.

  17. Theoretical approach to study the effect of free volumes on the physical behavior of polymer stabilized ferroelectric liquid crystal molecules

    Science.gov (United States)

    Lahiri, T.; Majumder, T. Pal

    2011-06-01

    It was clearly indicative that the polymer chains make a tremendous interaction with the tilt angle in case of a polymer stabilized ferroelectric liquid crystal (PSFLC). After suitable consideration of such interaction, we expanded the Landau free energy for a PSFLC system. We theoretically demonstrated the effect of free volumes, which expected to create bulk self-energy, on the physical functionalities of a PSFLC system. Then we obtained spontaneous polarization, tilt angle, rotational viscosity and dielectric constant strongly correlated with the assumed interactions. We also observed a shift of transition temperature highly influenced by this interaction between polymer network and liquid crystal molecules. A microscopical picture of this polymer-liquid crystal interaction is provided in view of the free volume charge density present in the composite system.

  18. Guidelines for selecting codes for ground-water transport modeling of low-level waste burial sites. Volume 1. Guideline approach

    Energy Technology Data Exchange (ETDEWEB)

    Simmons, C.S.; Cole, C.R.

    1985-05-01

    This document was written for the National Low-Level Waste Management Program to provide guidance for managers and site operators who need to select ground-water transport codes for assessing shallow-land burial site performance. The guidance given in this report also serves the needs of applications-oriented users who work under the direction of a manager or site operator. The guidelines are published in two volumes designed to support the needs of users having different technical backgrounds. An executive summary, published separately, gives managers and site operators an overview of the main guideline report. This volume includes specific recommendations for decision-making managers and site operators on how to use these guidelines. The more detailed discussions about the code selection approach are provided. 242 refs., 6 figs.

  19. The United States Remains Unprepared for Oil Import Disruptions. Volume II. Detailed Review of Current Emergency Programs and Alternative Approaches.

    Science.gov (United States)

    1981-09-29

    Conservation Act ERA Economic Regulatory Administration ERDO Emergency Reserve Drawdown Obligation ESS Emergency Sharing System ESSD Emergency Strategies and...a fraction of the base period volume. Each prime supplier (a refiner or wholesaler who first transports gasoline into a State) generally must use a...that State. Each prime supplier must set aside 5 percent of supply for this purpose. 1/See U.S. General Accounting Office, "Gasoline Allocation A Chaotic

  20. An artificial intelligence approach for modeling volume and fresh weight of callus - A case study of cumin (Cuminum cyminum L.).

    Science.gov (United States)

    Mansouri, Ali; Fadavi, Ali; Mortazavian, Seyed Mohammad Mahdi

    2016-05-21

    Cumin (Cuminum cyminum Linn.) is valued for its aroma and its medicinal and therapeutic properties. A supervised feedforward artificial neural network (ANN) trained with back propagation algorithms, was applied to predict fresh weight and volume of Cuminum cyminum L. calli. Pearson correlation coefficient was used to evaluate input/output dependency of the eleven input parameters. Area, feret diameter, minor axis length, perimeter and weighted density parameters were chosen as input variables. Different training algorithms, transfer functions, number of hidden nodes and training iteration were studied to find out the optimum ANN structure. The network with conjugate gradient fletcher-reeves (CGF) algorithm, tangent sigmoid transfer function, 17 hidden nodes and 2000 training epochs was selected as the final ANN model. The final model was able to predict the fresh weight and volume of calli more precisely relative to multiple linear models. The results were confirmed by R(2)≥0.89, R(i)≥0.94 and T value ≥0.86. The results for both volume and fresh weight values showed that almost 90% of data had an acceptable absolute error of ±5%.

  1. Estimating the volume and age of water stored in global lakes using a geo-statistical approach

    Science.gov (United States)

    Messager, Mathis Loïc; Lehner, Bernhard; Grill, Günther; Nedeva, Irena; Schmitt, Oliver

    2016-12-01

    Lakes are key components of biogeochemical and ecological processes, thus knowledge about their distribution, volume and residence time is crucial in understanding their properties and interactions within the Earth system. However, global information is scarce and inconsistent across spatial scales and regions. Here we develop a geo-statistical model to estimate the volume of global lakes with a surface area of at least 10 ha based on the surrounding terrain information. Our spatially resolved database shows 1.42 million individual polygons of natural lakes with a total surface area of 2.67 × 106 km2 (1.8% of global land area), a total shoreline length of 7.2 × 106 km (about four times longer than the world's ocean coastline) and a total volume of 181.9 × 103 km3 (0.8% of total global non-frozen terrestrial water stocks). We also compute mean and median hydraulic residence times for all lakes to be 1,834 days and 456 days, respectively.

  2. Additive manufacturing technology (direct metal laser sintering) as a novel approach to fabricate functionally graded titanium implants: preliminary investigation of fabrication parameters.

    Science.gov (United States)

    Lin, Wei-Shao; Starr, Thomas L; Harris, Bryan T; Zandinejad, Amirali; Morton, Dean

    2013-01-01

    This article describes the preliminary findings of the mechanical properties of functionally graded titanium with controlled distribution of porosity and a reduced Young's modulus on the basis of a computeraided design (CAD) file, using the rapid-prototyping, direct metal laser sintering (DMLS) technique. Sixty specimens of Ti-6Al-4V were created using a DMLS machine (M270) following the standard for tensile testing of metals. One group was fabricated with only 170 W of laser energy to create fully dense specimens (control group). The remaining specimens all featured an outer fully dense "skin" layer and a partially sintered porous inner "core" region. The outer "skin" of each specimen was scanned at 170 W and set at a thickness of 0.35, 1.00, or 1.50 mm for different specimen groups. The inner "core" of each specimen was scanned at a lower laser power (43 or 85 W). The partially sintered core was clearly visible in all specimens, with somewhat greater porosity with the lower laser power. However, the amount of porosity in the core region was not related to the laser power alone; thinner skin layers resulted in higher porosity for the same power values in the core structure. The lowest Young's modulus achieved, 35 GPa, is close to that of bone and was achieved with a laser power of 43 W and a skin thickness of 0.35 mm, producing a core that comprised 74% of the total volume. Additive manufacturing technology may provide an efficient alternative way to fabricate customized dental implants based on a CAD file with a functionally graded structure that may minimize stress shielding and improve the long-term performance of dental implants.

  3. Regioselectivity in the [2 + 2] cyclo-addition reaction of triplet carbonyl compounds to substituted alkenes (Paterno-Büchi reaction): A spin-polarized conceptual DFT approach

    Indian Academy of Sciences (India)

    B Pintér; F De Proft; T Veszprémi; P Geerlings

    2005-09-01

    Regioselectivity of the photochemical [2 + 2] cyclo-addition of triplet carbonyl compounds with a series of ground state electron-rich and electron-poor alkenes, the Paterno-Büchi reaction, is studied. Activation barriers for the first step of the triplet reaction are computed in the case of the O-attack. Next, the observed regioselectivity is explained using a series of DFT-based reactivity indices. In the first step, we use the local softness and the local HSAB principle within a softness matching approach, and explain the relative activation barriers of the addition step. In the final step, the regioselectivity is assessed within the framework of spin-polarized conceptual density functional theory, considering response functions of the system's external potential , number of electrons and spin number , being the difference between the number of and electrons in the spin-polarized system. Although the concept of local spin philicity, introduced recently within this theory, appears less suited to predict the regioselectivity in this reaction, the correct regioselectivity emerges from considering an interaction between the largest values of the generalized Fukui functions ss on both interacting molecules.

  4. Sex determination using discriminant analysis of upper and lower extremity bones: New approach using the volume and surface area of digital model.

    Science.gov (United States)

    Lee, U-Young; Kim, In-Beom; Kwak, Dai-Soon

    2015-08-01

    This study used 110 CT images taken from donated Korean cadavers to create 3-D models of the following upper and lower limb bones: the clavicle, scapula, humerus, radius, ulna, hip bone (os coxa), femur, patella (knee cap), tibia, talus, and calcaneus. In addition, the bone volume and surface area were calculated to determine sex differences using discriminant analysis. Significant sex differences were found in all bones with respect to volume and surface area (phip bone>tibia>humerus>scapula), although the order of surface area was different. The largest surface area in men was the femur and in women was the hip bone (psex determination (94%). When using the surface area of multiple bones, the maximum accuracy (99.4%) was achieved. The equation was as follows: (discriminant equation of surface area; femalesex determination.

  5. Application of the Price-Volume Approach in Cases of Innovative Drugs Where Value-Based Pricing is Inadequate: Description of Real Experiences in Italy.

    Science.gov (United States)

    Messori, Andrea

    2016-08-01

    Several cases of expensive drugs designed for large patient populations (e.g. sofosbuvir) have raised a complex question in terms of drug pricing. Even assuming value-based pricing, the treatment with these drugs of all eligible patients would have an immense budgetary impact, which is unsustainable also for the richest countries. This raises the need to reduce the prices of these agents in comparison with those suggested by the value-based approach and to devise new pricing methods that can achieve this goal. The present study discusses in detail the following two methods: (i) The approach based on setting nation-wide budget thresholds for individual innovative agents in which a fixed proportion of the historical pharmaceutical expenditure represents the maximum budget attributable to an innovative treatment; (ii) The approach based on nation-wide price-volume agreements in which drug prices are progressively reduced as more patients receive the treatment. The first approach has been developed in the USA by the Institute for Clinical and Economic Review and has been applied to PCSK9 inhibitors (alirocumab and evolocumab). The second approach has been designed for the Italian market and has found a systematic application to manage the price of ranibizumab, sofosbuvir, and PCSK9 inhibitors. While, in the past, price-volume agreements have been applied only on an empirical basis (i.e. in the absence of any quantitative theoretical rule), more recently some explicit mathematical models have been described. The performance of these models is now being evaluated on the basis of the real-world experiences conducted in some European countries, especially Italy.

  6. A novel geotechnical/geostatistical approach for exploration and production of natural gas from multiple geologic strata, Phase 1. Volume 1, Overview

    Energy Technology Data Exchange (ETDEWEB)

    Overbey, W.K. Jr.; Reeves, T.K.; Salamy, S.P.; Locke, C.D.; Johnson, H.R.; Brunk, R.; Hawkins, L. [BDM Engineering Services Co., Morgantown, WV (United States)

    1991-05-01

    This research program has been designed to develop and verify a unique geostatistical approach for finding natural gas resources. The research has been conducted by Beckley College, Inc. (Beckley) and BDM Engineering Services Company (BDMESC) under contract to the US Department of Energy (DOE), Morgantown Energy Technology Center. Phase 1 of the project consisted of compiling and analyzing relevant geological and gas production information in selected areas of Raleigh County, West Virginia, ultimately narrowed to the Eccles, West Virginia, 7 {1/2} minute Quadrangle. The Phase 1 analysis identified key parameters contributing to the accumulation and production of natural gas in Raleigh County, developed analog models relating geological factors to gas production, and identified specific sites to test and verify the analysis methodologies by drilling. Based on the Phase 1 analysis, five sites have been identified with high potential for economic gas production. Phase 2 will consist of drilling, completing, and producing one or more wells at the sites identified in the Phase 1 analyses. The initial well is schedules to the drilled in April 1991. This report summarizes the results of the Phase 1 investigations. For clarity, the report has been prepared in two volumes. Volume 1 presents the Phase 1 overview; Volume 2 contains the detailed geological and production information collected and analyzed for this study.

  7. REVIEW OF THE NEGOTIATION OF THE MODEL PROTOCOL ADDITIONAL TO THE AGREEMENT(S) BETWEEN STATE(S) AND THE INTERNATIONAL ATOMIC ENERGY AGENCY FOR THE APPLICATION OF SAFEGUARDS, INFCIRC/540 (Corrected) VOLUME II/III IAEA COMMITTEE 24, Major Issues Underlying the Model Additional Protocol (1996-1997).

    Energy Technology Data Exchange (ETDEWEB)

    Rosenthal, M.D.; Saum-Manning, L.; Houck, F.

    2010-01-01

    Volume I of this Review traces the origins of the Model Additional Protocol. It covers the period from 1991, when events in Iraq triggered an intensive review of the safeguards system, until 1996, when the IAEA Board of Governors established Committee 24 to negotiate a new protocol to safeguards agreement. The period from 1991-1996 set the stage for this negotiation and shaped its outcome in important ways. During this 5-year period, many proposals for strengthening safeguards were suggested and reviewed. Some proposals were dropped, for example, the suggestion by the IAEA Secretariat to verify certain imports, and others were refined. A rough consensus was established about the directions in which the international community wanted to go, and this was reflected in the draft of an additional protocol that was submitted to the IAEA Board of Governors on May 6, 1996 in document GOV/2863, Strengthening the Effectiveness and Improving the Efficiency of the Safeguards System - Proposals For Implementation Under Complementary Legal Authority, A Report by the Director General. This document ended with a recommendation that, 'the Board, through an appropriate mechanism, finalize the required legal instrument taking as a basis the draft protocol proposed by the Secretariat and the explanation of the measures contained in this document.'

  8. Trends in hydraulic fracturing distributions and treatment fluids, additives, proppants, and water volumes applied to wells drilled in the United States from 1947 through 2010: data analysis and comparison to the literature

    Science.gov (United States)

    Gallegos, Tanya J.; Varela, Brian A.

    2015-01-01

    Hydraulic fracturing is presently the primary stimulation technique for oil and gas production in low-permeability, unconventional reservoirs. Comprehensive, published, and publicly available information regarding the extent, location, and character of hydraulic fracturing in the United States is scarce. This national spatial and temporal analysis of data on nearly 1 million hydraulically fractured wells and 1.8 million fracturing treatment records from 1947 through 2010 (aggregated in Data Series 868) is used to identify hydraulic fracturing trends in drilling methods and use of proppants, treatment fluids, additives, and water in the United States. These trends are compared to the literature in an effort to establish a common understanding of the differences in drilling methods, treatment fluids, and chemical additives and of how the newer technology has affected the water use volumes and areal distribution of hydraulic fracturing. Historically, Texas has had the highest number of records of hydraulic fracturing treatments and associated wells in the United States documented in the datasets described herein. Water-intensive horizontal/directional drilling has also increased from 6 percent of new hydraulically fractured wells drilled in the United States in 2000 to 42 percent of new wells drilled in 2010. Increases in horizontal drilling also coincided with the emergence of water-based “slick water” fracturing fluids. As such, the most current hydraulic fracturing materials and methods are notably different from those used in previous decades and have contributed to the development of previously inaccessible unconventional oil and gas production target areas, namely in shale and tight-sand reservoirs. Publicly available derivative datasets and locations developed from these analyses are described.

  9. Investigation of Adaptive-threshold Approaches for Determining Area-Time Integrals from Satellite Infrared Data to Estimate Convective Rain Volumes

    Science.gov (United States)

    Smith, Paul L.; VonderHaar, Thomas H.

    1996-01-01

    The principal goal of this project is to establish relationships that would allow application of area-time integral (ATI) calculations based upon satellite data to estimate rainfall volumes. The research is being carried out as a collaborative effort between the two participating organizations, with the satellite data analysis to determine values for the ATIs being done primarily by the STC-METSAT scientists and the associated radar data analysis to determine the 'ground-truth' rainfall estimates being done primarily at the South Dakota School of Mines and Technology (SDSM&T). Synthesis of the two separate kinds of data and investigation of the resulting rainfall-versus-ATI relationships is then carried out jointly. The research has been pursued using two different approaches, which for convenience can be designated as the 'fixed-threshold approach' and the 'adaptive-threshold approach'. In the former, an attempt is made to determine a single temperature threshold in the satellite infrared data that would yield ATI values for identifiable cloud clusters which are closely related to the corresponding rainfall amounts as determined by radar. Work on the second, or 'adaptive-threshold', approach for determining the satellite ATI values has explored two avenues: (1) attempt involved choosing IR thresholds to match the satellite ATI values with ones separately calculated from the radar data on a case basis; and (2) an attempt involved a striaghtforward screening analysis to determine the (fixed) offset that would lead to the strongest correlation and lowest standard error of estimate in the relationship between the satellite ATI values and the corresponding rainfall volumes.

  10. Identifying Structure-Property Relationships Through DREAM.3D Representative Volume Elements and DAMASK Crystal Plasticity Simulations: An Integrated Computational Materials Engineering Approach

    Science.gov (United States)

    Diehl, Martin; Groeber, Michael; Haase, Christian; Molodov, Dmitri A.; Roters, Franz; Raabe, Dierk

    2017-03-01

    Predicting, understanding, and controlling the mechanical behavior is the most important task when designing structural materials. Modern alloy systems—in which multiple deformation mechanisms, phases, and defects are introduced to overcome the inverse strength-ductility relationship—give raise to multiple possibilities for modifying the deformation behavior, rendering traditional, exclusively experimentally-based alloy development workflows inappropriate. For fast and efficient alloy design, it is therefore desirable to predict the mechanical performance of candidate alloys by simulation studies to replace time- and resource-consuming mechanical tests. Simulation tools suitable for this task need to correctly predict the mechanical behavior in dependence of alloy composition, microstructure, texture, phase fractions, and processing history. Here, an integrated computational materials engineering approach based on the open source software packages DREAM.3D and DAMASK (Düsseldorf Advanced Materials Simulation Kit) that enables such virtual material development is presented. More specific, our approach consists of the following three steps: (1) acquire statistical quantities that describe a microstructure, (2) build a representative volume element based on these quantities employing DREAM.3D, and (3) evaluate the representative volume using a predictive crystal plasticity material model provided by DAMASK. Exemplarily, these steps are here conducted for a high-manganese steel.

  11. Identifying Structure-Property Relationships Through DREAM.3D Representative Volume Elements and DAMASK Crystal Plasticity Simulations: An Integrated Computational Materials Engineering Approach

    Science.gov (United States)

    Diehl, Martin; Groeber, Michael; Haase, Christian; Molodov, Dmitri A.; Roters, Franz; Raabe, Dierk

    2017-05-01

    Predicting, understanding, and controlling the mechanical behavior is the most important task when designing structural materials. Modern alloy systems—in which multiple deformation mechanisms, phases, and defects are introduced to overcome the inverse strength-ductility relationship—give raise to multiple possibilities for modifying the deformation behavior, rendering traditional, exclusively experimentally-based alloy development workflows inappropriate. For fast and efficient alloy design, it is therefore desirable to predict the mechanical performance of candidate alloys by simulation studies to replace time- and resource-consuming mechanical tests. Simulation tools suitable for this task need to correctly predict the mechanical behavior in dependence of alloy composition, microstructure, texture, phase fractions, and processing history. Here, an integrated computational materials engineering approach based on the open source software packages DREAM.3D and DAMASK (Düsseldorf Advanced Materials Simulation Kit) that enables such virtual material development is presented. More specific, our approach consists of the following three steps: (1) acquire statistical quantities that describe a microstructure, (2) build a representative volume element based on these quantities employing DREAM.3D, and (3) evaluate the representative volume using a predictive crystal plasticity material model provided by DAMASK. Exemplarily, these steps are here conducted for a high-manganese steel.

  12. Additivity dominance

    Directory of Open Access Journals (Sweden)

    Paul Rozin

    2009-10-01

    Full Text Available Judgments of naturalness of foods tend to be more influenced by the process history of a food, rather than its actual constituents. Two types of processing of a ``natural'' food are to add something or to remove something. We report in this study, based on a large random sample of individuals from six countries (France, Germany, Italy, Switzerland, UK and USA that additives are considered defining features of what makes a food not natural, whereas ``subtractives'' are almost never mentioned. In support of this, skim milk (with major subtraction of fat is rated as more natural than whole milk with a small amount of natural vitamin D added. It is also noted that ``additives'' is a common word, with a synonym reported by a native speaker in 17 of 18 languages, whereas ``subtractive'' is lexicalized in only 1 of the 18 languages. We consider reasons for additivity dominance, relating it to omission bias, feature positive bias, and notions of purity.

  13. Segmentation and additive approach: A reliable technique to study noncovalent interactions of large molecules at the surface of single-wall carbon nanotubes.

    Science.gov (United States)

    Torres, Ana M; Scheiner, Steve; Roy, Ajit K; Garay-Tapia, Andrés M; Bustamante, John; Kar, Tapas

    2016-08-05

    This investigation explores a new protocol, named Segmentation and Additive approach (SAA), to study exohedral noncovalent functionalization of single-walled carbon nanotubes with large molecules, such as polymers and biomolecules, by segmenting the entire system into smaller units to reduce computational cost. A key criterion of the segmentation process is the preservation of the molecular structure responsible for stabilization of the entire system in smaller segments. Noncovalent interaction of linoleic acid (LA, C18 H32 O2 ), a fatty acid, at the surface of a (10,0) zigzag nanotube is considered for test purposes. Three smaller segmented models have been created from the full (10,0)-LA system and interaction energies were calculated for these models and compared with the full system at different levels of theory, namely ωB97XD, LDA. The success of this SAA is confirmed as the sum of the interaction energies is in very good agreement with the total interaction energy. Besides reducing computational cost, another merit of SAA is an estimation of the contributions from different sections of the large system to the total interaction energy which can be studied in-depth using a higher level of theory to estimate several properties of each segment. On the negative side, bulk properties, such as HOMO-LUMO (highest occupied molecular orbital - lowest occupied molecular orbital) gap, of the entire system cannot be estimated by adding results from segment models. © 2016 Wiley Periodicals, Inc.

  14. Wisconsin Inventor & Entrepreneur Clubs: Investment in an Innovative Approach to Entrepreneurship. Rural Research Report. Volume 20, Issue 1, Winter 2009

    Science.gov (United States)

    Wise, Greg

    2009-01-01

    Research on entrepreneurship in rural areas has increasingly stressed the importance of a supportive environment and social networks in enhancing innovation. This report examines a novel approach to promoting entrepreneurship using regional Inventor & Entrepreneur (I&E) Clubs. A telephone survey of 21 I&E Clubs was completed to collect…

  15. Curriculum Assessment Using Artificial Neural Network and Support Vector Machine Modeling Approaches: A Case Study. IR Applications. Volume 29

    Science.gov (United States)

    Chen, Chau-Kuang

    2010-01-01

    Artificial Neural Network (ANN) and Support Vector Machine (SVM) approaches have been on the cutting edge of science and technology for pattern recognition and data classification. In the ANN model, classification accuracy can be achieved by using the feed-forward of inputs, back-propagation of errors, and the adjustment of connection weights. In…

  16. Wisconsin Inventor & Entrepreneur Clubs: Investment in an Innovative Approach to Entrepreneurship. Rural Research Report. Volume 20, Issue 1, Winter 2009

    Science.gov (United States)

    Wise, Greg

    2009-01-01

    Research on entrepreneurship in rural areas has increasingly stressed the importance of a supportive environment and social networks in enhancing innovation. This report examines a novel approach to promoting entrepreneurship using regional Inventor & Entrepreneur (I&E) Clubs. A telephone survey of 21 I&E Clubs was completed to collect information…

  17. Novel computational approach for studying ph effects, excluded volume and ion-ion correlations in electrical double layers around polyelectrolytes and nanoparticles

    Science.gov (United States)

    Ovanesyan, Zaven

    , which are important details for proper description of EDL properties. In this thesis, we implement an efficient and accurate classical solvation density functional theory (CDSFT) for EDLs of spherical macroions and cylindrical polyelectrolytes embedded in aqueous electrolytes. This approach extends the capabilities of mean field approximations by taking into account electrostatic ion-ion correlations, size asymmetry and excluded volume effects without compromising the computational cost. We apply the computational tool to study the structural and thermodynamic properties of the ionic atmosphere around B-DNA and spherical nanoparticles. We demonstrate that the presence of solvent molecules at experimental concentration and size values has a significant impact on the layering of ions. This layering directly influences the integrated charge and mean electrostatic potential in the diffuse region of the spherical electrical double layer (SEDL) and have a noticeable impact on the behavior of zeta potential (ZP). Recently, we have extended the aforementioned CSDFT to account for the charge-regulated mechanisms of the macroion surface on the structural and thermodynamic properties of spherical EDLs. In the approach, the CSDFT is combined with a surface complexation model to account for ion correlation and excluded volume effects on the surface titration of spherical macroions. We apply the proposed computational approach to describe the role that the ion size and solvent excluded volume play on the surface titration properties of silica nanoparticles. We analyze the effects of the nanoparticle size, pH and salt concentration of the aqueous solution on the nanoparticle's surface charge and zeta potential. The results reveal that surface charge density and zeta potential significantly depend on excluded volume and ion-ion correlation effects as well as on pH for monovalent ion species at high salt concentrations. Overall, our results are in good agreement with Monte Carlo

  18. Potlining Additives

    Energy Technology Data Exchange (ETDEWEB)

    Rudolf Keller

    2004-08-10

    In this project, a concept to improve the performance of aluminum production cells by introducing potlining additives was examined and tested. Boron oxide was added to cathode blocks, and titanium was dissolved in the metal pool; this resulted in the formation of titanium diboride and caused the molten aluminum to wet the carbonaceous cathode surface. Such wetting reportedly leads to operational improvements and extended cell life. In addition, boron oxide suppresses cyanide formation. This final report presents and discusses the results of this project. Substantial economic benefits for the practical implementation of the technology are projected, especially for modern cells with graphitized blocks. For example, with an energy savings of about 5% and an increase in pot life from 1500 to 2500 days, a cost savings of $ 0.023 per pound of aluminum produced is projected for a 200 kA pot.

  19. Additivity dominance

    OpenAIRE

    2009-01-01

    Judgments of naturalness of foods tend to be more influenced by the process history of a food, rather than its actual constituents. Two types of processing of a ``natural'' food are to add something or to remove something. We report in this study, based on a large random sample of individuals from six countries (France, Germany, Italy, Switzerland, UK and USA) that additives are considered defining features of what makes a food not natural, whereas ``subtractives'' are almost never mentioned....

  20. Sulfite Additives

    OpenAIRE

    1988-01-01

    The CMA recommends that sulfites be banned as food preservatives when satisfactory and safe alternatives are available. When there is no suitable substitute strict labelling requirements on foods should be imposed for sulfite additives. The association supports the efforts of the Health Protection Branch of the Department of National Health and Welfare to regulate sulfites in the food and drug industry to prevent adverse reactions in people sensitive to sulfites. The CMA recommends that the D...

  1. Model estimation of cerebral hemodynamics between blood flow and volume changes: a data-based modeling approach.

    Science.gov (United States)

    Wei, Hua-Liang; Zheng, Ying; Pan, Yi; Coca, Daniel; Li, Liang-Min; Mayhew, J E W; Billings, Stephen A

    2009-06-01

    It is well known that there is a dynamic relationship between cerebral blood flow (CBF) and cerebral blood volume (CBV). With increasing applications of functional MRI, where the blood oxygen-level-dependent signals are recorded, the understanding and accurate modeling of the hemodynamic relationship between CBF and CBV becomes increasingly important. This study presents an empirical and data-based modeling framework for model identification from CBF and CBV experimental data. It is shown that the relationship between the changes in CBF and CBV can be described using a parsimonious autoregressive with exogenous input model structure. It is observed that neither the ordinary least-squares (LS) method nor the classical total least-squares (TLS) method can produce accurate estimates from the original noisy CBF and CBV data. A regularized total least-squares (RTLS) method is thus introduced and extended to solve such an error-in-the-variables problem. Quantitative results show that the RTLS method works very well on the noisy CBF and CBV data. Finally, a combination of RTLS with a filtering method can lead to a parsimonious but very effective model that can characterize the relationship between the changes in CBF and CBV.

  2. A volume-preserving sharpening approach for the propagation of sharp phase boundaries in multiphase lattice Boltzmann simulations

    KAUST Repository

    Reis, T.

    2011-07-01

    Lattice Boltzmann models that recover a macroscopic description of multiphase flow of immiscible liquids typically represent the boundaries between phases using a scalar function, the phase field, that varies smoothly over several grid points. Attempts to tune the model parameters to minimise the widths of these interfaces typically lead to the interfaces becoming fixed to the underlying grid instead of advecting with the fluid velocity. This phenomenon, known as lattice pinning, is strikingly similar to that associated with the numerical simulation of conservation laws coupled to stiff algebraic source terms. We present a lattice Boltzmann formulation of the model problem proposed by LeVeque and Yee (1990) [3] to study the latter phenomenon in the context of computational combustion, and offer a volume-conserving extension in multiple space dimensions. Inspired by the random projection method of Bao and Jin (2000) [1] we further generalise this formulation by introducing a uniformly distributed quasi-random variable into the term responsible for the sharpening of phase boundaries. This method is mass conserving, gives correct average propagation speeds over many timesteps, and is shown to significantly delay the onset of pinning as the interface width is reduced. © 2010 Elsevier Ltd.

  3. Alternative proofs for Kocik's Geometric Diagram for Relativistic Velocity Addition

    CERN Document Server

    Sasane, Amol

    2015-01-01

    A geometric construction for the Poincare formula for relativistic addition of velocities in one dimension was given by Jerzy Kocik in "Geometric Diagram for Relativistic Addition of Velocities", American Journal of Physics, volume 80, page 737, 2012. While the proof given there used Cartesian coordinate geometry, three alternative approaches are given in this article: a trigonometric one, one via Euclidean geometry, and one using projective geometry.

  4. Proceedings of RIKEN BNL Research Center Workshop: The Approach to Equilibrium in Strongly Interacting Matter. Volume 118

    Energy Technology Data Exchange (ETDEWEB)

    Liao, J. [Brookhaven National Lab. (BNL), Upton, NY (United States); Venugopalan, R. [Brookhaven National Lab. (BNL), Upton, NY (United States); Berges, J. [Brookhaven National Lab. (BNL), Upton, NY (United States); Blaizot, J. -P. [Brookhaven National Lab. (BNL), Upton, NY (United States); Gelis, F. [Brookhaven National Lab. (BNL), Upton, NY (United States)

    2014-04-09

    The RIKEN BNL Research Center (RBRC) was established in April 1997 at Brookhaven National Laboratory*. It is funded by the ''Rikagaku Kenkyusho'' (RIKEN, The Institute of Physical and Chemical Research) of Japan and the U. S. Department of Energy’s Office of Science. The RBRC is dedicated to the study of strong interactions, including spin physics, lattice QCD, and RHIC physics through the nurturing of a new generation of young physicists. The RBRC has theory, lattice gauge computing and experimental components. It is presently exploring the possibility of an astrophysics component being added to the program. The purpose of this Workshop is to critically review the recent progress on the theory and phenomenology of early time dynamics in relativistic heavy ion collisions from RHIC to LHC energies, to examine the various approaches on thermalization and existing issues, and to formulate new research efforts for the future. Topics slated to be covered include Experimental evidence for equilibration/isotropization, comparison of various approaches, dependence on the initial conditions and couplings, and turbulent cascades and Bose-Einstein condensation.

  5. Predictors and outcomes of lead extraction requiring a bailout femoral approach: Data from 2 high-volume centers.

    Science.gov (United States)

    El-Chami, Mikhael F; Merchant, Faisal M; Waheed, Anam; Khattak, Furqan; El-Khalil, Jad; Patel, Adarsh; Sayegh, Michael N; Desai, Yaanik; Leon, Angel R; Saba, Samir

    2017-04-01

    Lead extraction (LE) infrequently requires the use of the "bailout" femoral approach. Predictors and outcomes of femoral extraction are not well characterized. The aim of this study was to determine the predictors of need for femoral LE and its outcomes. Consecutive patients who underwent LE at our centers were identified. Baseline demographic characteristics, procedural outcomes, and clinical outcomes were ascertained by medical record review. Patients were stratified into 2 groups on the basis of the need for femoral extraction. A total of 1080 patients underwent LE, of whom 50 (4.63%) required femoral extraction. Patients requiring femoral extraction were more likely to have leads with longer dwell time (9.5 ± 6.0 years vs 5.7 ± 4.3 years; P extracted per procedure (2.0 ± 1.0 vs 1.7 ± 0.9; P = .003), and to have infection as an indication for extraction (72% vs 37.2%; P extraction group than in the nonfemoral group (58% and 76% vs 94.7% and 97.9 %, respectively; P extraction was needed in ~5% of LEs. Longer lead dwell time, higher number of leads extracted per procedure, and the presence of infection predicted the need for femoral extraction. Procedural success of femoral extraction was low, highlighting the fact that this approach is mostly used as a bailout strategy and thus selects for more challenging cases. Copyright © 2017 Heart Rhythm Society. Published by Elsevier Inc. All rights reserved.

  6. The volume of a soliton

    Energy Technology Data Exchange (ETDEWEB)

    Adam, C., E-mail: adam@fpaxp1.usc.es [Departamento de Física de Partículas, Universidad de Santiago de Compostela and Instituto Galego de Física de Altas Enerxias (IGFAE), E-15782 Santiago de Compostela (Spain); Haberichter, M. [School of Mathematics, Statistics and Actuarial Science, University of Kent, Canterbury, CT2 7NF (United Kingdom); Wereszczynski, A. [Institute of Physics, Jagiellonian University, Lojasiewicza 11, Kraków (Poland)

    2016-03-10

    There exists, in general, no unique definition of the size (volume, area, etc., depending on dimension) of a soliton. Here we demonstrate that the geometric volume (area etc.) of a soliton is singled out in the sense that it exactly coincides with the thermodynamical or continuum-mechanical volume. In addition, this volume may be defined uniquely for rather arbitrary solitons in arbitrary dimensions.

  7. Morphologic Study of Superior Temporal Sulcus-Amygdaloid Body and Lateral Fissure-Amygdaloid Body Surgical Approach by Using Magnetic Resonance Imaging Volume Rendering.

    Science.gov (United States)

    Qu, Yuan; Ren, Bichen; Chang, Xiaoyu; Zhang, Jinnan; Li, Youqiong; Duan, Haobo; Cheng, Kailiang; Wang, Jincheng

    2016-01-01

    In this research, 83 patients were measured by magnetic resonance imaging volume rendering technique. The authors acquired the curve length of the superior temporal sulcus and the lateral fissure on the cerebral hemisphere, the shortest distance from the superior temporal sulcus and the lateral fissure to the center of amygdaloid body separately, the vertical diameter, the transversal diameter, and the anteroposterior diameter of the amygdaloid body and the 2 approach angles between the median sagittal plane and the shortest segment from the superior temporal sulcus to the center of amygdaloid body and the shortest segment from lateral fissure to the center of the amygdaloid body. At the same time, we preliminarily oriented the 2 points of the superior temporal sulcus and the lateral fissure, which are closest to the center of amygdaloid body, aimed at finding out the best entrance points of surgical approach through the superior temporal sulcus and the lateral fissure to the amygdaloid body and reducing the damage to the nerve fibers or blood vessels during the operation. The results indicate that the point at the front side 1/4 of the superior temporal sulcus may be the ideal surgical approach entrance point and the point at the front side 1/3 of the lateral fissure. There is no difference between 2 cerebral hemispheres (P < 0.05).

  8. Perfusion MRI (dynamic susceptibility contrast imaging) with different measurement approaches for the evaluation of blood flow and blood volume in human gliomas

    DEFF Research Database (Denmark)

    Thomsen, H; Steffensen, E; Larsson, Elna-Marie

    2012-01-01

    technique arterial spin labelling (ASL) presently provides measurement only of cerebral blood flow (CBF), which has not been widely used in human brain tumor studies. Purpose: To assess if measurement of blood flow is comparable with measurement of blood volume in human biopsy-proven gliomas obtained by DSC......, and glioblastomas. Results: rCBF and rCBV measurements obtained with the maximum perfusion method were correlated when normalized to white matter (r ¼ 0.60) and to the cerebellum (r ¼ 0.49). Histogram analyses of rCBF and rCBV showed that mean and median values as well as skewness and peak position were correlated......-MRI using two different regions for normalization and two different measurement approaches. Material and Methods: Retrospective study of 61 patients with different types of gliomas examined with DSC perfusion MRI. Regions of interest (ROIs) were placed in tumor portions with maximum perfusion on rCBF and r...

  9. The effects of ultrasound guidance and neurostimulation on the minimum effective anesthetic volume of mepivacaine 1.5% required to block the sciatic nerve using the subgluteal approach.

    Science.gov (United States)

    Danelli, Giorgio; Ghisi, Daniela; Fanelli, Andrea; Ortu, Andrea; Moschini, Elisa; Berti, Marco; Ziegler, Stefanie; Fanelli, Guido

    2009-11-01

    We tested the hypothesis that ultrasound (US) guidance may reduce the minimum effective anesthetic volume (MEAV(50)) of 1.5% mepivacaine required to block the sciatic nerve with a subgluteal approach compared with neurostimulation (NS). After premedication and single-injection femoral nerve block, 60 patients undergoing knee arthroscopy were randomly allocated to receive a sciatic nerve block with either NS (n = 30) or US (n = 30). In the US group, the sciatic nerve was localized between the ischial tuberosity and the greater trochanter. In the NS group, the appropriate muscular response (foot plantar flexion or inversion) was elicited (1.5 mA, 2 Hz, 0.1 ms) and maintained to mepivacaine required to block the sciatic nerve compared with NS.

  10. Multi-Disciplinary Approaches to Intelligently Sharing Large-Volumes of Real-Time Sensor Data During Natural Disasters

    Directory of Open Access Journals (Sweden)

    Stuart E Middleton

    2013-02-01

    Full Text Available We describe our knowledge-based service architecture for multi-risk environmental decision-support, capable of handling geo-distributed heterogeneous real-time data sources. Data sources include tide gauges, buoys, seismic sensors, satellites, earthquake alerts, Web 2.0 feeds to crowd source 'unconventional' measurements, and simulations of Tsunami wave propagation. Our system of systems multi-bus architecture provides a scalable and high performance messaging backbone. We are overcoming semantic interoperability between heterogeneous datasets by using a self-describing 'plug-in' data source approach. As crises develop we can agilely steer the processing server and adapt data fusion and mining algorithm configurations in real-time.

  11. Methodological approaches to planar and volumetric scintigraphic imaging of small volume targets with high spatial resolution and sensitivity

    Energy Technology Data Exchange (ETDEWEB)

    Mejia, J.; Galvis-Alonso, O.Y. [Faculdade de Medicina de Sao Jose do Rio Preto (FAMERP), SP (Brazil). Faculdade de Medicina. Dept. de Biologia Molecular], e-mail: mejia_famerp@yahoo.com.br; Braga, J. [Faculdade de Medicina de Sao Jose do Rio Preto (FAMERP), SP (Brazil). Div. de Astrofisica; Correa, R. [Instituto Nacional de Pesquisas Espaciais (INPE), Sao Jose dos Campos, SP (Brazil). Div. de Ciencia Espacial e Atmosferica; Leite, J.P. [Faculdade de Medicina de Sao Jose do Rio Preto (FAMERP), SP (Brazil). Dept. de Neurologia, Psiquiatria e Psicologia Medica; Simoes, M.V. [Faculdade de Medicina de Sao Jose do Rio Preto (FAMERP), SP (Brazil). Dept. de Clinica Medica

    2009-08-15

    Single-photon emission computed tomography (SPECT) is a non-invasive imaging technique, which provides information reporting the functional states of tissues. SPECT imaging has been used as a diagnostic tool in several human disorders and can be used in animal models of diseases for physiopathological, genomic and drug discovery studies. However, most of the experimental models used in research involve rodents, which are at least one order of magnitude smaller in linear dimensions than man. Consequently, images of targets obtained with conventional gamma-cameras and collimators have poor spatial resolution and statistical quality. We review the methodological approaches developed in recent years in order to obtain images of small targets with good spatial resolution and sensitivity. Multi pinhole, coded mask- and slit-based collimators are presented as alternative approaches to improve image quality. In combination with appropriate decoding algorithms, these collimators permit a significant reduction of the time needed to register the projections used to make 3-D representations of the volumetric distribution of target's radiotracers. Simultaneously, they can be used to minimize artifacts and blurring arising when single pinhole collimators are used. Representation images are presented, which illustrate the use of these collimators. We also comment on the use of coded masks to attain tomographic resolution with a single projection, as discussed by some investigators since their introduction to obtain near-field images. We conclude this review by showing that the use of appropriate hardware and software tools adapted to conventional gamma-cameras can be of great help in obtaining relevant functional information in experiments using small animals. (author)

  12. Computer-assisted venous thrombosis volume quantification.

    Science.gov (United States)

    Puentes, John; Dhibi, Mounir; Bressollette, Luc; Guias, Bruno; Solaiman, Basel

    2009-03-01

    Venous thrombosis (VT) volume assessment, by verifying its risk of progression when anticoagulant or thrombolytic therapies are prescribed, is often necessary to screen life-threatening complications. Commonly, VT volume estimation is done by manual delineation of few contours in the ultrasound (US) image sequence, assuming that the VT has a regular shape and constant radius, thus producing significant errors. This paper presents and evaluates a comprehensive functional approach based on the combination of robust anisotropic diffusion and deformable contours to calculate VT volume in a more accurate manner when applied to freehand 2-D US image sequences. Robust anisotropic filtering reduces image speckle noise without generating incoherent edge discontinuities. Prior knowledge of the VT shape allows initializing the deformable contour, which is then guided by the noise-filtering outcome. Segmented contours are subsequently used to calculate VT volume. The proposed approach is integrated into a system prototype compatible with existing clinical US machines that additionally tracks the acquired images 3-D position and provides a dense Delaunay triangulation required for volume calculation. A predefined robust anisotropic diffusion and deformable contour parameter set enhances the system usability. Experimental results pertinence is assessed by comparison with manual and tetrahedron-based volume computations, using images acquired by two medical experts of eight plastic phantoms and eight in vitro VTs, whose independently measured volume is the reference ground truth. Results show a mean difference between 16 and 35 mm(3) for volumes that vary from 655 to 2826 mm(3). Two in vivo VT volumes are also calculated to illustrate how this approach could be applied in clinical conditions when the real value is unknown. Comparative results for the two experts differ from 1.2% to 10.08% of the smallest estimated value when the image acquisition cadences are similar.

  13. The PAVE (peeling-assisted volume-enhancing) lift: A retrospective 6-year clinical analysis of a combined approach for facial rejuvenation.

    Science.gov (United States)

    Kaye, Kai Oliver; Schaller, Hans-Eberhard; Jaminet, Patrick; Gonser, Phillipp

    2016-08-01

    The peeling-assisted volume-enhancing (PAVE) lift is a single-stage approach that combines superficial musculoaponeurotic system (SMAS) plication techniques with fat grafting and different peeling agents. To evaluate the safety of this approach, we analyzed the records of 159 patients who underwent surgery between 2008 and 2014. The percentage of complications observed was not higher than values reported in the literature for each treatment entity: surgical facelift: n=3 haematomas (1.89 %), n=2; temporary apraxia of the mandibular branch (1.26%); fat transfer: minor asymmetry in n = 5 cases (3.14%); peeling: temporary hyperpigmentation in trichloroacetic acid (n = 5; 3.8%) and phenol peels (n = 4; 3.1%), permanent hypopigmentation (n = 6; 5.6%), formation of skin miliae persisting longer than 2 to 3 months (n = 5; 4.6%) and prolonged erythema (n = 3; 0.28%) in phenol peels. The single-stage use of chemical peels, autologous fat transfer, and surgical rhytidectomy was safe.

  14. Generalized Partial Volume

    DEFF Research Database (Denmark)

    Darkner, Sune; Sporring, Jon

    2011-01-01

    Mutual Information (MI) and normalized mutual information (NMI) are popular choices as similarity measure for multimodal image registration. Presently, one of two approaches is often used for estimating these measures: The Parzen Window (PW) and the Generalized Partial Volume (GPV). Their theoret......Mutual Information (MI) and normalized mutual information (NMI) are popular choices as similarity measure for multimodal image registration. Presently, one of two approaches is often used for estimating these measures: The Parzen Window (PW) and the Generalized Partial Volume (GPV...

  15. Determination of organic additives in mortars by near-IR spectroscopy. A novel approach to designing a sample set with high-variability components.

    Science.gov (United States)

    Blanco, Marcelo; Peguero, Anna

    2007-02-01

    Industrial mortars consist primarily of a mixture of cement and an aggregate plus a small amount of additives that are used to modify specific properties. Using too high or too low additive rates usually results in the loss of desirable properties in the end product. This entails carefully controlling the amounts of additives added to mortar in order to ensure correct dosing and/or adequate homogeneity in the final mixture. Near-IR (NIR) spectroscopy has proved effective for this purpose as it requires no sample pretreatment and affords expeditious analyses. The purpose of this work was to determine two organic additives (viz. Ad1 and Ad2) in mortars by using partial least squares regression multivariate calibration models constructed from NIR spectroscopic data. The additives are used to expedite setting and increase cohesion between particles in the mortar. In order to ensure that the sample set contained natural variability in the samples, we used a methodology based on experimental design to construct a representative set of samples. This novel design is based on a hexagonal antiprism that encompasses the concentration ranges spanned by the analytes and the variability inherent in each additive. The D-optimality criterion was used to obtain various combinations between Ad1 and Ad2 additive classes. The partial least squares calibration models thus constructed for each additive provided accurate predictions: the intercept and the slope of the plots of predicted values versus reference values for each additive were close to 0 and 1, respectively, and their confidence ranges included the respective value. The ensuing analytical methods were validated by using an external sample set.

  16. Volume Entropy

    CERN Document Server

    Astuti, Valerio; Rovelli, Carlo

    2016-01-01

    Building on a technical result by Brunnemann and Rideout on the spectrum of the Volume operator in Loop Quantum Gravity, we show that the dimension of the space of the quadrivalent states --with finite-volume individual nodes-- describing a region with total volume smaller than $V$, has \\emph{finite} dimension, bounded by $V \\log V$. This allows us to introduce the notion of "volume entropy": the von Neumann entropy associated to the measurement of volume.

  17. Bronchoscopic lung volume reduction

    Directory of Open Access Journals (Sweden)

    M. I. Polkey

    2006-12-01

    Full Text Available Surgical lung volume reduction can improve exercise performance and forced expiratory volume in one second in patients with emphysema. However, the procedure is associated with a 5% mortality rate and a nonresponse rate of 25%. Accordingly, interest has focused on alternative ways of reducing lung volume. Two principle approaches are used: collapse of the diseased area using blockers placed endobronchially and the creation of extrapulmonary pathways. Preliminary data from the former approach suggest that it can be successful and that the magnitude of success is related to reduction in dynamic hyperinflation.

  18. From additivity to synergism

    DEFF Research Database (Denmark)

    Ritz, Christian; Streibig, Jens Carl

    2014-01-01

    Interest in synergistic or antagonistic effects through mixture experiments has grown immensely over the past two decades, not the least within in pharmacology and toxicology. Several definitions of reference models exist; one commonly used reference model is concentration or dose addition, which...... assumes compounds, when administrated simultaneously, do not interfere with each other at the site of action. We focus on statistical modelling that allows evaluation of dose addition. We will describe several statistical approaches that are suitable for analysis mixture data where synergistic...... or antagonistic effects may be present. The statistical models are defined and explained and some of the approaches exemplified. Code in open-source software is provided....

  19. Part 1. Approaches to the total synthesis of the diterpene marrubin. Part II. Ligand assisted nucleophilic additions. Part III. Coal processing in a non-dissolving medium

    Energy Technology Data Exchange (ETDEWEB)

    Lipscombe, J.; Charles, W. II

    1987-01-01

    The total synthesis of the diterpene marrubiin was attempted using methodology previously developed in the Liotta laboratories. Ligand Assisted Nucleophilic Additions (LANA) comprise a new class of synthetic reactions involving the stereoselective addition of some group, usually in an intramolecular conjugate fashion. This group is itself derived from an earlier nucleophilic addition to a carbonyl moiety. Exchange of the original metal of the alkoxide with a second metal (which must be at least divalent) having a transferrable group demands that the stereochemistry of the first addition control the second. The general features of these types of processes are discussed. Initial work with substituted quinones is presented, and some mechanistic rationales are given. A novel method of coal processing at modest temperatures and hydrogen pressures (250-300/sup 0/C, 8.0 MPa) is discussed. Coals reacted with small amounts of tetrahydroquinoline in the presence of fluorocarbons or other non-dissolving media underwent astounding increases in pyridine solubility, a common standard in coal liquefaction studies. Several additives were employed, although only tetrahydroquinoline was found to effectively increase coal solubility. Coals having vastly different individual properties behaved similarly under these conditions. Kinetic and model studies were used in an attempt to clarify the reactions occurring under these novel conditions.

  20. A New Chemical Additives Adding Equipment for Paper Machine Slurry Approach Flow Pipe%纸机中助留剂加入设备介绍

    Institute of Scientific and Technical Information of China (English)

    祁红影

    2011-01-01

    The traditional and new equipment for adding retention aid solution to the approach flow pipe was introduced, and their advantages and disadvantages were also compared in this paper.%主要介绍发传统助留剂加入设备和新型助留剂加入设备,并对比了它们的优缺点.

  1. Basic-functionalized recyclable ionic liquid catalyst: A solvent-free approach for Michael addition of 1,3-dicarbonyl compounds to nitroalkenes under ultrasound irradiation.

    Science.gov (United States)

    Narayanaperumal, Senthil; da Silva, Rodrigo César; Feu, Karla Santos; de la Torre, Alexander Fernández; Corrêa, Arlene G; Paixão, Márcio Weber

    2013-05-01

    A task-specific ionic liquid (TSIL) has been introduced as a recyclable catalyst in Michael addition. A series of nitroalkenes and various C-based nucleophiles were reacted in the presence of 30mol% of recyclable basic-functionalized ionic liquid. Good to excellent yields were obtained in 30min under ultrasound irradiation.

  2. Preliminary results of tests of proprietary chemical additives, seeding, and other approaches for the reduction of scale in hypersaline geothermal systems

    Energy Technology Data Exchange (ETDEWEB)

    Harrar, J.E.; Locke, F.E.; Otto, C.H. Jr.; Deutscher, S.B.; Lim, R.; Frey, W.P.; Quong, R.; Lorensen, L.E.

    1979-02-01

    The LLL field brine-scaling test system and a variety of measurement techniques have been used to test a group of eight proprietary additives from eight different companies, a hydroxyethylcellulose previously found to retard silica precipitation, and geothermal sludge as a seeding agent to reduce scaling. For each additive, scaling rates at both 210 and 125/sup 0/C and on three different materials--mild steel, Teflon, and Hastelloy C-276--were measured using test coupons. Sections of steel pipe and perforated screens also were exposed to the treated brine, silica precipitation rates in the effluent brine were measured by means of the electrochemical linear polarization resistance technique. Examination of the pipe sections and chemical analyses of the scales are not complete, thus only preliminary conclusions are reported here. It appears that, although none of the additives effected a dramatic reduction in scaling rates, several decreased the rate of scaling of mild steel at 125/sup 0/C by a factor of 2 to 3. Only hydroxyethylcellulose retards the rate of precipitation of silica in the effluent brine. Scaling rates could not be measured accurately in the seeding experiment because of its short duration, but this brine treatment had the desired effect, at 125/sup 0/C, of reducing the level of dissolved silica and hence the scaling tendency of the brine. Further experiments of this type will be conducted.

  3. Design for volume reduction

    NARCIS (Netherlands)

    Wever, R.; Boks, C.; Stevels, A.

    2007-01-01

    Traditionally packaging design-for-sustainability (DfS) strongly focuses on resource conservation and material recycling. The type and amount of materials used has been the driver in design. For consumer electronics (CE) products this weight-based approach is too limited; a volume-based approach is

  4. Dry lake beds as sources of dust in Australia during the Late Quaternary: A volumetric approach based on lake bed and deflated dune volumes

    Science.gov (United States)

    Farebrother, Will; Hesse, Paul P.; Chang, Hsing-Chung; Jones, Claudia

    2017-04-01

    Dust affects Earth's climate, ecology and economies across a broad range of scales, both temporally and spatially, and is an integral part of the earth's climate system. Previous studies have highlighted the importance of inland lake beds to dust emissions both locally and globally. This study aims to explore the relative volumetric importance of ephemeral lakes that emit dust to the Australian southeastern dust path over the last glacial cycle. SRTM DEMs and GIS analyses of long-term (up to 80 ka) lake-bed deflation volumes and deposition of sand-sized sediment onto downwind source bordering dunes were used to derive estimates of transported dust mass. A strong power relationship was found between lake area and the mass of deflated lake bed sediments. Total dust masses for the largest 53 lakes in southeastern Australia were derived using the relationship between lake area and dust mass and used to determine an upper value for total dust mass deflated from lake beds in southeastern Australia. Ephemeral lake-derived dust was found to represent at most 13% of the dust derived from southeastern Australia deposited in the southern Pacific over the last 80 ka or 22% over the last 40 ka. Lake Eyre (the largest lake) has contributed at most 3% of the Australian southeast dust plume. These results imply that there are significant additional sources of dust in Australia over these timescales, such as floodplains or dunefields, and that modelling must allow for diverse climatic and geomorphic controls on dust production.

  5. Priming of soil carbon decomposition in two inner Mongolia grassland soils following sheep dung addition: A study using13C natural abundance approach

    DEFF Research Database (Denmark)

    Ma, Xiuzhi; Ambus, Per; Wang, Shiping;

    2013-01-01

    -amended controls. In both grassland soils, ca. 60% of the evolved CO2 originated from the decomposing sheep dung and 40% from the native soil C. Priming effects of soil C decomposition were observed in both soils, i.e. 1.4 g and 1.6 g additional soil C kg-1 dry soil had been emitted as CO2 for the L. chinensis...... may cause a net soil C loss due to the positive priming effect, thereby accelerating soil deterioration. © 2013 Ma et al....

  6. Perfusion MRI (dynamic susceptibility contrast imaging) with different measurement approaches for the evaluation of blood flow and blood volume in human gliomas

    Energy Technology Data Exchange (ETDEWEB)

    Thomsen, H. (Den Sundhedsfaglige Kandidatuddannelse, Aarhus Universitet Bygning 1264, Aarhus (Denmark); University College Nordjylland, Aalborg (Denmark)), Email: hnt@ucn.dk; Steffensen, E. (Aalborg Hospital/Aarhus University Hospital, Department of Radiology, Aalborg (Denmark)); Larsson, E. M. (Aalborg Hospital/Aarhus University Hospital, Department of Radiology, Aalborg (Denmark); Uppsala University Hospital, Department of Radiology, Uppsala (Sweden))

    2012-02-15

    Background. Perfusion magnetic resonance imaging (MRI) is increasingly used in the evaluation of brain tumors. Relative cerebral blood volume (rCBV) is usually obtained by dynamic susceptibility contrast (DSC) MRI using normal appearing white matter as reference region. The emerging perfusion technique arterial spin labelling (ASL) presently provides measurement only of cerebral blood flow (CBF), which has not been widely used in human brain tumor studies. Purpose. To assess if measurement of blood flow is comparable with measurement of blood volume in human biopsy-proven gliomas obtained by DSC-MRI using two different regions for normalization and two different measurement approaches. Material and Methods. Retrospective study of 61 patients with different types of gliomas examined with DSC perfusion MRI. Regions of interest (ROIs) were placed in tumor portions with maximum perfusion on rCBF and rCBV maps, with contralateral normal appearing white matter and cerebellum as reference regions. Larger ROIs were drawn for histogram analyses. The type and grade of the gliomas were obtained by histopathology. Statistical comparison was made between diffuse astrocytomas, anaplastic astrocytomas, and glioblastomas. Results. rCBF and rCBV measurements obtained with the maximum perfusion method were correlated when normalized to white matter (r = 0.60) and to the cerebellum (r = 0.49). Histogram analyses of rCBF and rCBV showed that mean and median values as well as skewness and peak position were correlated (0.61 < r < 0.93), whereas for kurtosis and peak height, the correlation coefficient was about 0.3 when comparing rCBF and rCBV values for the same reference region. Neither rCBF nor rCBV quantification provided a statistically significant difference between the three types of gliomas. However, both rCBF and rCBV tended to increase with tumor grade and to be lower in patients who had undergone resection/treatment. Conclusion. rCBF measurements normalized to white matter

  7. Additivity rule for electron-molecule total cross section calculations at 50-5000 eV: a new geometrical approach

    Institute of Scientific and Technical Information of China (English)

    Shi De-Heng; Sun Jin-Feng; Zhu Zun-Lüe; Liu Yu-Fang

    2008-01-01

    Taking into consideration the changes of the geometric shielding effect in a molecule as the energy of incident electrons varies, this paper presents an empirical fraction, which depends on the energy of incident electrons, the target's molecular dimension and the atomic and electronic numbers in the molecule. Using this empirical fraction, it proposes a new formulation of the additivity rule. Employing the new additivity rule, it calculates the total cross sections of electron scattering by C2H4, C6H8, C6H14 and C8H18 over the energy range from 50 to 5000eV. In order to exclude the calculation deviations caused by solving the radial SchriJdinger equation of electron scattering by atoms, here the atomic cross sections are derived from the experimental total cross section results of simple molecules (H2,O2, CO) via the inversion algorithm. The quantitative total cross sections are compared with those obtained by experiments and other theories, and good agreement is obtained over a wide energy range, even at energy of several tens of eV.

  8. Initial in vitro screening approach to investigate the potential health and environmental hazards of Envirox™ – a nanoparticulate cerium oxide diesel fuel additive

    Directory of Open Access Journals (Sweden)

    Whittingham Andrew

    2007-12-01

    Full Text Available Abstract Nanotechnology is the new industrial revolution of the 21st Century as the various processes lead to radical improvements in medicine, manufacturing, energy production, land remediation, information technology and many other everyday products and applications. With this revolution however, there are undoubted concerns for health, safety and the environment which arise from the unique nature of materials and processes at the nanometre scale. The in vitro assays used in the screening strategy are all validated, internationally accepted protocols and provide a useful indication of potential toxicity of a chemical as a result of effects on various toxicological endpoints such as local site of contact (dermal irritation, general cytotoxicity and mutagenicity. The initial in vitro screening strategy described in this paper to investigate the potential health implications, if any, which may arise following exposure to one specific application of nanoparticulate cerium oxide used as a diesel fuel borne catalyst, reflects a precautionary approach and the results will inform judgement on how best to proceed to ensure safe use.

  9. Priming of soil carbon decomposition in two Inner Mongolia grassland soils following sheep dung addition: a study using ¹³C natural abundance approach.

    Directory of Open Access Journals (Sweden)

    Xiuzhi Ma

    Full Text Available To investigate the effect of sheep dung on soil carbon (C sequestration, a 152 days incubation experiment was conducted with soils from two different Inner Mongolian grasslands, i.e. a Leymus chinensis dominated grassland representing the climax community (2.1% organic matter content and a heavily degraded Artemisia frigida dominated community (1.3% organic matter content. Dung was collected from sheep either fed on L. chinensis (C3 plant with δ¹³C = -26.8‰; dung δ¹³C = -26.2‰ or Cleistogenes squarrosa (C₄ plant with δ¹³C = -14.6‰; dung δ¹³C = -15.7‰. Fresh C₃ and C₄ sheep dung was mixed with the two grassland soils and incubated under controlled conditions for analysis of ¹³C-CO₂ emissions. Soil samples were taken at days 17, 43, 86, 127 and 152 after sheep dung addition to detect the δ¹³C signal in soil and dung components. Analysis revealed that 16.9% and 16.6% of the sheep dung C had decomposed, of which 3.5% and 2.8% was sequestrated in the soils of L. chinensis and A. frigida grasslands, respectively, while the remaining decomposed sheep dung was emitted as CO₂. The cumulative amounts of C respired from dung treated soils during 152 days were 7-8 times higher than in the un-amended controls. In both grassland soils, ca. 60% of the evolved CO₂ originated from the decomposing sheep dung and 40% from the native soil C. Priming effects of soil C decomposition were observed in both soils, i.e. 1.4 g and 1.6 g additional soil C kg⁻¹ dry soil had been emitted as CO₂ for the L. chinensis and A. frigida soils, respectively. Hence, the net C losses from L. chinensis and A. frigida soils were 0.6 g and 0.9 g C kg⁻¹ soil, which was 2.6% and 7.0% of the total C in L. chinensis and A. frigida grasslands soils, respectively. Our results suggest that grazing of degraded Inner Mongolian pastures may cause a net soil C loss due to the positive priming effect, thereby accelerating soil

  10. Refining the Indications for the Addition of Orbital Osteotomy during Anterior Cranial Base Approaches: Morphometric and Radiologic Study of the Anterior Cranial Base Osteology.

    Science.gov (United States)

    DeBattista, Juan Carlos; Andaluz, Norberto; Zuccarello, Mario; Kerr, Robert G; Keller, Jeffrey T

    2014-08-01

    Objectives In anatomic and radiologic morphometric studies, we examine a predictive method, based on preoperative imaging of the anterior cranial base, to define when addition of orbital osteotomy is warranted. Design Anatomic and radiographic study. Setting In 100 dry skulls, measurements in the anterior cranial fossa included three lines and two angles based on computerized tomography (CT) scans taken in situ and validated using frameless stereotactic navigation. The medial angle (coronal plane) was the intersection between the highest point of both orbits and the midpoint between the two frontoethmoidal sutures to each orbital roof high point. The oblique angle (sagittal plane) was the intersection at the midpoint of the limbus sphenoidale. Results No identifiable morphometric patterns were found for our classification of anterior fossae; the two-tailed distribution pattern was similar for all skulls, disproving the hypothetical correlation between visual appearance and morphometry. Orbital heights (range: 6.6-18.7 mm) showed a linear relationship with medial and oblique angles, and they had a linear distribution relative to angular increments. Orbital heights > 11 mm were associated with angles ≥ 20 degrees and more likely to benefit from orbitotomy. Conclusion Preoperative CT measurement of orbital height appears feasible for predicting when orbitotomy is needed, and it warrants further testing.

  11. Biphasic DC measurement approach for enhanced measurement stability and multi-channel sampling of self-sensing multi-functional structural materials doped with carbon-based additives

    Science.gov (United States)

    Downey, Austin; D'Alessandro, Antonella; Ubertini, Filippo; Laflamme, Simon; Geiger, Randall

    2017-06-01

    Investigation of multi-functional carbon-based self-sensing structural materials for structural health monitoring applications is a topic of growing interest. These materials are self-sensing in the sense that they can provide measurable electrical outputs corresponding to physical changes such as strain or induced damage. Nevertheless, the development of an appropriate measurement technique for such materials is yet to be achieved, as many results in the literature suggest that these materials exhibit a drift in their output when measured with direct current (DC) methods. In most of the cases, the electrical output is a resistance and the reported drift is an increase in resistance from the time the measurement starts due to material polarization. Alternating current methods seem more appropriate at eliminating the time drift. However, published results show they are not immune to drift. Moreover, the use of multiple impedance measurement devices (LCR meters) does not allow for the simultaneous multi-channel sampling of multi-sectioned self-sensing materials due to signal crosstalk. The capability to simultaneously monitor multiple sections of self-sensing structural materials is needed to deploy these multi-functional materials for structural health monitoring. Here, a biphasic DC measurement approach with a periodic measure/discharge cycle in the form of a square wave sensing current is used to provide consistent, stable resistance measurements for self-sensing structural materials. DC measurements are made during the measurement region of the square wave while material depolarization is obtained during the discharge region of the periodic signal. The proposed technique is experimentally shown to remove the signal drift in a carbon-based self-sensing cementitious material while providing simultaneous multi-channel measurements of a multi-sectioned self-sensing material. The application of the proposed electrical measurement technique appears promising for real

  12. Estimation of Relative Blood Volume in Head and Neck Tumors

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    @@ Introduction: The calculation of relative blood volume in head and neck tumor with MR imaging is anew approach that may provide additional hemodynamic information relevant to both untreated and treated tumors. This hemodynamic information is especially usefu l for the differentiation between viable tumor and postsurgical changes or rad iation induced scar, and is also beneficial for tumor staging and tumor biopsy.

  13. Two prophylactic medication approaches in addition to a pain control regimen for early medical abortion misoprostol: study protocol for a randomized, controlled trial.

    Science.gov (United States)

    Dragoman, Monica V; Grossman, Daniel; Kapp, Nathalie; Huong, Nguyen My; Habib, Ndema; Dung, Duong Lan; Tamang, Anand

    2016-10-12

    study completion. Although pain is one of the most common side effects encountered with medical abortion, little is known about optimal pain management for this process. This multi-arm trial design offers an efficient approach to evaluating two prophylactic pain management regimens compared to use of pain medication as needed. ACTRN12613000017729 (Prospectively registered 8/1/2013).

  14. October 2015 Phoenix pulmonary journal club: lung volume reduction

    Directory of Open Access Journals (Sweden)

    Mathew M

    2015-11-01

    Full Text Available No abstract available. Article truncated at 150 words. The October 2015 pulmonary journal club focused on the review of older studies evaluating lung volume reduction surgery and how this has transitioned toward the development of non-surgical modes of lung volume reduction. The physiology behind dyspnea in chronic obstructive pulmonary disease (COPD is a complex process. One of the proposed mechanisms has been hyperinflation associated with air trapping. In the mid 1990s studies by Cooper and Peterson (1 offered a promising approach in which lung volume reduction (LVR could improve ventilatory mechanics and improve dyspnea. As the procedure gained more popularity, additional larger scale trials were performed to support its validity. We reviewed 2 studies looking at lung volume reduction. The first was "The Effect of Lung Volume Reduction Surgery In Patients With Severe Emphysema” (2 . This was a smaller, randomized controlled trial (RCT that looked at 2 groups of 24 patients. Once group received LVR while the ...

  15. Utility of Quantitative 99mTc-MAA SPECT/CT for 90yttrium-Labelled Microsphere Treatment Planning: Calculating Vascularized Hepatic Volume and Dosimetric Approach

    Directory of Open Access Journals (Sweden)

    Etienne Garin

    2011-01-01

    Full Text Available Objectives. The aim of this study was to assess the effectiveness of SPECT/CT for volume measurements and to report a case illustrating the major impact of SPECT/CT in calculating the vascularized liver volume and dosimetry prior to injecting radiolabelled yttrium-90 microspheres (Therasphere. Materials and Methods. This was a phantom study, involving volume measurements carried out by two operators using SPECT and SPECT/CT images. The percentage of error for each method was calculated, and interobserver reproducibility was evaluated. A treatment using Therasphere was planned in a patient with three hepatic arteries, and the quantitative analysis of SPECT/CT for this patient is provided. Results. SPECT/CT volume measurements proved to be accurate (mean error <6% for volumes ≥16 cm3 and reproductive (interobserver agreement = 0.9. In the case report, 99mTc-MAA SPECT/CT identified a large liver volume, not previously identified with angiography, which was shown to be vascularized after selective MAA injection into an arterial branch, resulting in a large modification in the activity of Therasphere used. Conclusions. MAA SPECT/CT is accurate for vascularized liver volume measurements, providing a valuable contribution to the therapeutic planning of patients with complex hepatic vascularization.

  16. What Is the Standard Volume to Increase a Cup Size for Breast Augmentation Surgery? A Novel Three-Dimensional Computed Tomographic Approach.

    Science.gov (United States)

    King, Nina-Marie; Lovric, Vedran; Parr, William C H; Walsh, W R; Moradi, Pouria

    2017-05-01

    Breast augmentation surgery poses many challenges, and meeting the patient's expectations is one of the most important. Previous reports equate 100 cc to a one-cup-size increase; however, no studies have confirmed this between commercially available bras. The aim of this study was to identify the volume increase between cup sizes across different brands and the relationship with implant selection. Five bra cup sizes from three different companies were analyzed for their volume capacity. Three methods were used to calculate the volume of the bras: (1) linear measurements; (2) volume measurement by means of water displacement; and (3) volume calculation after three-dimensional reconstruction of serial radiographic data (computed tomography). The clinical arm consisted of 79 patients who underwent breast augmentation surgery from February 1, 2014, to June 30, 2016. Answers from a short questionnaire in combination with the implant volume were analyzed. Across all three brands, the interval volume increase varied between sizes, but not all were above 100 cc. There was some variation in the volume capacity of the same cup size among the different brands. The average incremental increase in bra cup size across all three brands in the laboratory arm was 135 cc. The mean volume increase per cup size was 138.23 cc in the clinical arm. This article confirms that there is no standardization within the bra manufacturing industry. On the basis of this study, patients should be advised that 130 to 150 cc equates to a one-cup-size increase. Bras with narrower band widths need 130 cc and wider band widths require 150 cc to increase one cup size.

  17. Enhancement of antimicrobial activities of whole and sub-fractionated white tea by addition of copper (II sulphate and vitamin C against Staphylococcus aureus; a mechanistic approach

    Directory of Open Access Journals (Sweden)

    Holloway Andrew C

    2011-11-01

    Full Text Available Abstract Background Enhancement of antimicrobial plant products e.g. pomegranate extract by copper (II sulphate is known. Such combinations have applications in various settings, including the identification of novel compositions to study, treat and control infection. Methods A combination of white tea (WT (made allowing 10 minutes infusion time at 100°C was combined with 4.8 mM copper (II sulphate and tested for antimicrobial effect on the viability of Staphylococcus aureus NCTC 06571. Comparisons were made with green (GT and black (BT teas. A WT sub-fraction (WTF Results A 30 minute incubation at room temperature of copper (II sulphate alone and combined with WT reduced the viability of S. aureus NCTC 06571 by c.a 1 log10 cfu mL-1. GT and BT with copper (II sulphate negated activity to buffer values. Combined with copper (II sulphate, vitamin C, WTF and, vitamin C plus WTF all reduced the viability of S. aureus NCTC 06571 by c.a. 3.5 log10 cfu mL-1. Independent experiments showed the results were not due to pH effects. Adding WT or WTF to copper (II sulphate resulted in increased acidity. Copper (II sulphate alone and combined with WT required c.a 300 μg mL-1 (final concentration catalase to restore S. aureus viability, WTF with copper (II sulphate and added vitamin C required c.a 600 μg mL-1. WT and WTF UV-visible spectra were similar. Conclusions WT showed no efficacy in the combinations tested. WTF was enhanced with copper (II sulphate and further with vitamin C. WT and WTF increased acidity of copper (II sulphate possibly via the formation of chemical complexes. The difference in WT/WTF absorbance possibly represented substances less concentrated or absent in WTF. Investigations to establish which WTF component/s and in what proportions additives are most effective against target organisms are warranted.

  18. Determination of sample size for a multi-class classifier based on single-nucleotide polymorphisms: a volume under the surface approach.

    Science.gov (United States)

    Liu, Xinyu; Wang, Yupeng; Sriram, T N

    2014-06-14

    Data on single-nucleotide polymorphisms (SNPs) have been found to be useful in predicting phenotypes ranging from an individual's class membership to his/her risk of developing a disease. In multi-class classification scenarios, clinical samples are often limited due to cost constraints, making it necessary to determine the sample size needed to build an accurate classifier based on SNPs. The performance of such classifiers can be assessed using the Area Under the Receiver Operating Characteristic (ROC) Curve (AUC) for two classes and the Volume Under the ROC hyper-Surface (VUS) for three or more classes. Sample size determination based on AUC or VUS would not only guarantee an overall correct classification rate, but also make studies more cost-effective. For coded SNP data from D(≥2) classes, we derive an optimal Bayes classifier and a linear classifier, and obtain a normal approximation to the probability of correct classification for each classifier. These approximations are then used to evaluate the associated AUCs or VUSs, whose accuracies are validated using Monte Carlo simulations. We give a sample size determination method, which ensures that the difference between the two approximate AUCs (or VUSs) is below a pre-specified threshold. The performance of our sample size determination method is then illustrated via simulations. For the HapMap data with three and four populations, a linear classifier is built using 92 independent SNPs and the required total sample sizes are determined for a continuum of threshold values. In all, four different sample size determination studies are conducted with the HapMap data, covering cases involving well-separated populations to poorly-separated ones. For multi-classes, we have developed a sample size determination methodology and illustrated its usefulness in obtaining a required sample size from the estimated learning curve. For classification scenarios, this methodology will help scientists determine whether a sample

  19. Unsteady flow volumes

    Energy Technology Data Exchange (ETDEWEB)

    Becker, B.G.; Lane, D.A.; Max, N.L.

    1995-03-01

    Flow volumes are extended for use in unsteady (time-dependent) flows. The resulting unsteady flow volumes are the 3 dimensional analog of streamlines. There are few examples where methods other than particle tracing have been used to visualize time varying flows. Since particle paths can become convoluted in time there are additional considerations to be made when extending any visualization technique to unsteady flows. We will present some solutions to the problems which occur in subdivision, rendering, and system design. We will apply the unsteady flow volumes to a variety of field types including moving multi-zoned curvilinear grids.

  20. The evidence-base for conceptual approaches and additional therapies targeting lower limb function in children with cerebral palsy: a systematic review using the International Classification of Functioning, Disability and Health as a framework

    OpenAIRE

    Franki, Inge; Desloovere, Kaat; De Cat, Josse; Feys, Hilde; Molenaers, Guy; Calders, Patrick; Vanderstraeten, Guy; Himpens, Eveline; Van den Broeck, Christine

    2012-01-01

    Objective: This systematic review provides an overview of the effectiveness of conceptual approaches and additional therapies used in lower limb physical therapy of children with cerebral palsy and supports the development of clinical guidelines. Data sources and study selection: A literature search in 5 electronic databases was performed, extracting literature published between 1995 and 2009. Studies were evaluated using the framework recommended by the American Academy for Cerebral Pals...

  1. Renormalized Volumes with Boundary

    CERN Document Server

    Gover, A Rod

    2016-01-01

    We develop a general regulated volume expansion for the volume of a manifold with boundary whose measure is suitably singular along a separating hypersurface. The expansion is shown to have a regulator independent anomaly term and a renormalized volume term given by the primitive of an associated anomaly operator. These results apply to a wide range of structures. We detail applications in the setting of measures derived from a conformally singular metric. In particular, we show that the anomaly generates invariant (Q-curvature, transgression)-type pairs for hypersurfaces with boundary. For the special case of anomalies coming from the volume enclosed by a minimal hypersurface ending on the boundary of a Poincare--Einstein structure, this result recovers Branson's Q-curvature and corresponding transgression. When the singular metric solves a boundary version of the constant scalar curvature Yamabe problem, the anomaly gives generalized Willmore energy functionals for hypersurfaces with boundary. Our approach ...

  2. Determination of Shale Volume and Distribution Patterns and Effective Porosity from Well Log Data Based On Cross-Plot Approach for A Shaly Carbonate Gas Reservoir

    Science.gov (United States)

    Moradi, Siyamak; Moeini, Mohammad; Kamal Ghassem al-Askari, Mohammad; Hamed Mahvelati, Elaheh

    2016-10-01

    Determination of shale volume distribution is one of the most important factors that has to be considered in formation evaluation, since existence of shale reduces effective porosity and permeability of the reservoir. In this paper, shale volume and distribution (dispersed, laminar and structural) and formation effective porosity are estimated from well log data and cross-plots. Results show that distribution of shale is mainly dispersed with few of laminar ones, and the quality of reservoir (effective porosity) decreases with depth resulting in low productivity of gas wells drilled in lower zones. Good agreement of estimated shale volumes and effective porosities from neutron-density cross-plot with the values determined from gamma ray log (CGR) and core analysis demonstrates the accuracy and applicability of these plots in determination of petrophysical parameters from conventional log data.

  3. Effect the addition of 10% (volume fraction) chromium on the mechanical properties of NiAlCr processed by powder metallurgy; Efecto de la adicion de un 10% en volumen de cromo en el comportamiento a traccion de aleaciones pulvimetalurgicas NiAlCr

    Energy Technology Data Exchange (ETDEWEB)

    Garcia-Barriocanal, J.; Garces, G.; Perez, P.; Adeva, P.

    2005-07-01

    The mechanical properties of Ni{sub 3}Al-Cr reinforced with 10% in volume fraction of chromium particles produced by powder metallurgy have been studied. For this purpose, milled powders with composition of Ni-20.9Al-8Cr-0.49B (% st.) with and without the addition of 10% in volume fraction of chromium particles have been produced. Both alloys were consolidated by hot isostatic pressing (HIP). After HIP, heat treatment was applied to homogenize the microstructure. The chromium reinforcement has an important effect in the yield strength and ultimate strength increase. The reinforced alloy presents a yield strength of 1300 MPa at room temperature with respect to 800 MPa for the un-reinforced material. After heat treatment, the yield strength of both alloys does not change significantly. However, a decrease in ductility and ultimate tensile strength have been observed. (Author) 4 refs.

  4. Use of a theoretical equation of state to interpret time-dependent free volume in polymer glasses

    Energy Technology Data Exchange (ETDEWEB)

    Curro, J.G.; Lagasse, R.R.; Simha, R.

    1981-10-01

    Many physical properties of polymer glasses change spontaneously during isothermal aging by a process commonly modeled as collapse of free volume. The model has not been verified rigorously because free volume cannot be unambiguously measured. In the present investigation we tentatively identify the free-volume fraction with the fraction of empty sites in the equation of state of Simha and Somcynsky. With this theory, volume recovery measurements can be analyzed to yield directly the time-dependent, free-volume fraction. Using this approach, recent volume measurements on poly(methyl methacrylate) are analyzed. The resulting free-volume fractions are then used in the Doolittle equation to predict the shift in stress relaxation curves at 23 /sup 0/C. These predicted shift factors agree with the experimental measurements of Cizmecioglu et al. In addition, it is shown that previous assumptions concerning temperature dependence of free volume are inconsistent with the theory.

  5. Use of a theoretical equation of state to interpret time-dependent free volume in polymer glasses

    Science.gov (United States)

    Curro, J. G.; Lagasse, R. R.; Simha, R.

    1981-10-01

    Many physical properties of polymer glasses change spontaneously during isothermal aging by a process commonly modeled as collapse of free volume. The model has not been verified rigorously because free volume cannot be unambiguously measured. In the present investigation we tentatively identify the free-volume fraction with the fraction of empty sites in the equation of state of Simha and Somcynsky. With this theory, volume recovery measurements can be analyzed to yield directly the time-dependent, free-volume fraction. Using this approach, recent volume measurements on poly(methyl methacrylate) are analyzed. The resulting free-volume fractions are then used in the Doolittle equation to predict the shift in stress relaxation curves at 23 °C. These predicted shift factors agree with the experimental measurements of Cizmecioglu et al. In addition, it is shown that previous assumptions concerning temperature dependence of free volume are inconsistent with the theory.

  6. Liquid Metering Centrifuge Sticks (LMCS): A Centrifugal Approach to Metering Known Sample Volumes for Colorimetric Solid Phase Extraction (C-SPE)

    Science.gov (United States)

    Gazda, Daniel B.; Schultz, John R.; Clarke, Mark S.

    2007-01-01

    Phase separation is one of the most significant obstacles encountered during the development of analytical methods for water quality monitoring in spacecraft environments. Removing air bubbles from water samples prior to analysis is a routine task on earth; however, in the absence of gravity, this routine task becomes extremely difficult. This paper details the development and initial ground testing of liquid metering centrifuge sticks (LMCS), devices designed to collect and meter a known volume of bubble-free water in microgravity. The LMCS uses centrifugal force to eliminate entrapped air and reproducibly meter liquid sample volumes for analysis with Colorimetric Solid Phase Extraction (C-SPE). C-SPE is a sorption-spectrophotometric platform that is being developed as a potential spacecraft water quality monitoring system. C-SPE utilizes solid phase extraction membranes impregnated with analyte-specific colorimetric reagents to concentrate and complex target analytes in spacecraft water samples. The mass of analyte extracted from the water sample is determined using diffuse reflectance (DR) data collected from the membrane surface and an analyte-specific calibration curve. The analyte concentration can then be calculated from the mass of extracted analyte and the volume of the sample analyzed. Previous flight experiments conducted in microgravity conditions aboard the NASA KC-135 aircraft demonstrated that the inability to collect and meter a known volume of water using a syringe was a limiting factor in the accuracy of C-SPE measurements. Herein, results obtained from ground based C-SPE experiments using ionic silver as a test analyte and either the LMCS or syringes for sample metering are compared to evaluate the performance of the LMCS. These results indicate very good agreement between the two sample metering methods and clearly illustrate the potential of utilizing centrifugal forces to achieve phase separation and metering of water samples in microgravity.

  7. A Study of the Transient Response of Duct Junctions: Measurements and Gas-Dynamic Modeling with a Staggered Mesh Finite Volume Approach

    Directory of Open Access Journals (Sweden)

    Antonio J. Torregrosa

    2017-05-01

    Full Text Available Duct junctions play a major role in the operation and design of most piping systems. The objective of this paper is to establish the potential of a staggered mesh finite volume model as a way to improve the description of the effect of simple duct junctions on an otherwise one-dimensional flow system, such as the intake or exhaust of an internal combustion engine. Specific experiments have been performed in which different junctions have been characterized as a multi-port, and that have provided precise and reliable results on the propagation of pressure pulses across junctions. The results obtained have been compared to simulations performed with a staggered mesh finite volume method with different flux limiters and different meshes and, as a reference, have also been compared with the results of a more conventional pressure loss-based model. The results indicate that the staggered mesh finite volume model provides a closer description of wave dynamics, even if further work is needed to establish the optimal calculation settings.

  8. A statistical approach based on substitution of macronutrients provides additional information to models analyzing single dietary factors in relation to type 2 diabetes in danish adults: the Inter99 study.

    Science.gov (United States)

    Faerch, Kristine; Lau, Cathrine; Tetens, Inge; Pedersen, Oluf Borbye; Jørgensen, Torben; Borch-Johnsen, Knut; Glümer, Charlotte

    2005-05-01

    Most studies analyzing diet-disease relations focus on single dietary factors rather than combining different nutrients into the same statistical model. The objective of this study was to identify dietary factors associated with the probability of having diabetes identified by screening (SDM) in Danish men and women aged 30-60 y. A specific objective was to examine whether an alternative statistical approach could provide additional information to already existing statistical approaches used in nutritional epidemiology. Baseline data from the Danish population-based Inter99 study were used. The dietary intake of 262 individuals with SDM was compared with that of 4627 individuals with normal glucose tolerance (NGT) using 2 different types of multiple logistic regression models adjusted for potential confounders. The first model included single dietary factors, whereas the second model was based on substitution of macronutrients. In the models with single dietary factors, high intakes of carbohydrates, dietary fiber, and coffee were inversely associated with SDM (P < 0.01), whereas high intakes of total fat and saturated fat were positively associated with SDM (P < 0.05). A modest U-shaped association was found between alcohol consumption and SDM (P = 0.10) [corrected] Results from the substitution model showed that when 3% of energy (En%) as carbohydrate replaced 3 En% fat or alcohol, the probability of having SDM decreased by 9 and 10%, respectively (P < 0.01) [corrected] No other macronutrient substitutions resulted in significant associations. Hence, the statistical approach based on substitution of macronutrients provided additional information to the model analyzing single dietary factors.

  9. Renormalized Volume

    Science.gov (United States)

    Gover, A. Rod; Waldron, Andrew

    2017-09-01

    We develop a universal distributional calculus for regulated volumes of metrics that are suitably singular along hypersurfaces. When the hypersurface is a conformal infinity we give simple integrated distribution expressions for the divergences and anomaly of the regulated volume functional valid for any choice of regulator. For closed hypersurfaces or conformally compact geometries, methods from a previously developed boundary calculus for conformally compact manifolds can be applied to give explicit holographic formulæ for the divergences and anomaly expressed as hypersurface integrals over local quantities (the method also extends to non-closed hypersurfaces). The resulting anomaly does not depend on any particular choice of regulator, while the regulator dependence of the divergences is precisely captured by these formulæ. Conformal hypersurface invariants can be studied by demanding that the singular metric obey, smoothly and formally to a suitable order, a Yamabe type problem with boundary data along the conformal infinity. We prove that the volume anomaly for these singular Yamabe solutions is a conformally invariant integral of a local Q-curvature that generalizes the Branson Q-curvature by including data of the embedding. In each dimension this canonically defines a higher dimensional generalization of the Willmore energy/rigid string action. Recently, Graham proved that the first variation of the volume anomaly recovers the density obstructing smooth solutions to this singular Yamabe problem; we give a new proof of this result employing our boundary calculus. Physical applications of our results include studies of quantum corrections to entanglement entropies.

  10. Preliminary design study of underground pumped hydro and compressed-air energy storage in hard rock. Volume 8: Design approaches: UPH. Appendix A: Upper reservoir

    Science.gov (United States)

    1981-04-01

    Overriding considerations including operating range, volume and lining of reservoir, embankment design, intake/outlet arrangements and filling and make up water provisions were studied within the context of minimizing facility costs and optimizing the plant layout. The study led to the selection of a reservoir formed by embankment of compacted rockfill together with an intake/outlet structure located in the embankment. The reservoir floor and upstream slopes of the embankment will have an asphalt lining to prevent leakage. The material and cost estimates presented are based on the requirements for a 2000 MW plant providing 20,000 MWh of storage with a nominal head of 4600 ft.

  11. Finite volume corrections to pi pi scattering

    Energy Technology Data Exchange (ETDEWEB)

    Sato, Ikuro; Bedaque, Paulo F.; Walker-Loud, Andre

    2006-01-13

    Lattice QCD studies of hadron-hadron interactions are performed by computing the energy levels of the system in a finite box. The shifts in energy levels proportional to inverse powers of the volume are related to scattering parameters in a model independent way. In addition, there are non-universal exponentially suppressed corrections that distort this relation. These terms are proportional to e-m{sub pi} L and become relevant as the chiral limit is approached. In this paper we report on a one-loop chiral perturbation theory calculation of the leading exponential corrections in the case of I=2 pi pi scattering near threshold.

  12. 6715 Volume 12 No. 6 October 2012 NATURAL ADDITIVES ...

    African Journals Online (AJOL)

    DR AKIN OSO

    2012-10-06

    Oct 6, 2012 ... Department of Food Technology, Faculty of Technology, University of Ibadan, Ibadan. Nigeria. 2 ..... Trend of the plot showed increase in free fatty acid with increase incubation time. -1.00 ..... Hashhad, I. R, Iran, 2008. 24.

  13. Evaluation of Additive Manufacturing for High Volume Composite Part Molds

    Energy Technology Data Exchange (ETDEWEB)

    Duty, Chad E. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Kunc, Vlastimil [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Lokitz, Bradley S. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Springfield, Robert M. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)

    2017-05-01

    ORNL worked with TruDesign, LLC to develop viable coating solutions to enable the use of large scale 3D printing for both low-temperature and high-temperature composite molds. This project resulted in two commercial products and successfully demonstrated the use of printed molds for autoclave processing for the first time.

  14. The Differential Equation Algorithm for General Deformed Swept Volumes

    Institute of Scientific and Technical Information of China (English)

    汪国平; 华宣积; 孙家广

    2000-01-01

    The differential equation approach for characterizing swept volume boundaries is extended to include objects experiencing deformation. For deformed swept volume, it is found that the structure and algorithm of sweep-envelope differential equation (SEDE) are similar between the deformed and the rigid swept volumes. The efficiency of SEDE approach for deformed swept volume is proved with an example.

  15. Physical activity over a decade modifies age-related decline in perfusion, gray matter volume, and functional connectivity of the posterior default-mode network-A multimodal approach.

    Science.gov (United States)

    Boraxbekk, Carl-Johan; Salami, Alireza; Wåhlin, Anders; Nyberg, Lars

    2016-05-01

    One step toward healthy brain aging may be to entertain a physically active lifestyle. Studies investigating physical activity effects on brain integrity have, however, mainly been based on single brain markers, and few used a multimodal imaging approach. In the present study, we used cohort data from the Betula study to examine the relationships between scores reflecting current and accumulated physical activity and brain health. More specifically, we first examined if physical activity scores modulated negative effects of age on seven resting state networks previously identified by Salami, Pudas, and Nyberg (2014). The results revealed that one of the most age-sensitive RSN was positively altered by physical activity, namely, the posterior default-mode network involving the posterior cingulate cortex (PCC). Second, within this physical activity-sensitive RSN, we further analyzed the association between physical activity and gray matter (GM) volumes, white matter integrity, and cerebral perfusion using linear regression models. Regions within the identified DMN displayed larger GM volumes and stronger perfusion in relation to both current and 10-years accumulated scores of physical activity. No associations of physical activity and white matter integrity were observed. Collectively, our findings demonstrate strengthened PCC-cortical connectivity within the DMN, larger PCC GM volume, and higher PCC perfusion as a function of physical activity. In turn, these findings may provide insights into the mechanisms of how long-term regular exercise can contribute to healthy brain aging. Copyright © 2015 The Authors. Published by Elsevier Inc. All rights reserved.

  16. Additive Manufacturing of Hybrid Circuits

    Science.gov (United States)

    Sarobol, Pylin; Cook, Adam; Clem, Paul G.; Keicher, David; Hirschfeld, Deidre; Hall, Aaron C.; Bell, Nelson S.

    2016-07-01

    There is a rising interest in developing functional electronics using additively manufactured components. Considerations in materials selection and pathways to forming hybrid circuits and devices must demonstrate useful electronic function; must enable integration; and must complement the complex shape, low cost, high volume, and high functionality of structural but generally electronically passive additively manufactured components. This article reviews several emerging technologies being used in industry and research/development to provide integration advantages of fabricating multilayer hybrid circuits or devices. First, we review a maskless, noncontact, direct write (DW) technology that excels in the deposition of metallic colloid inks for electrical interconnects. Second, we review a complementary technology, aerosol deposition (AD), which excels in the deposition of metallic and ceramic powder as consolidated, thick conformal coatings and is additionally patternable through masking. Finally, we show examples of hybrid circuits/devices integrated beyond 2-D planes, using combinations of DW or AD processes and conventional, established processes.

  17. Preliminary design study of underground pumped hydro and compressed-air energy storage in hard rock. Volume 8: Design approaches. UPH. Appendix E: Lower reservoir

    Science.gov (United States)

    1981-04-01

    Operational, construction, and geotechnical requirements were examined. Overriding considerations including operating range, volume, construction methods, cavern cross section and reservoir layout were studied within the context of minimizing facility costs and optimizing the plant layout. The study led to a preliminary arrangement of fourteen parallel caverns, each 60 ft wide by 85 ft high in cross section and 3610 ft in length. The requirements for and preliminary design of the intermediate reservoir in the case of a two step UPH facility is also described. The design and the cost estimates presented are based on the requirements for a 2000 MW plant providing 20,000 MWh of storage at a nominal head of 4600 ft.

  18. Attempts to Improve Absolute Quantification of Cerebral Blood Flow in Dynamic Susceptibility Contrast Magnetic Resonance Imaging: A Simplified T1-Weighted Steady-State Cerebral Blood Volume Approach

    Energy Technology Data Exchange (ETDEWEB)

    Wirestam, R.; Knutsson, L.; Risberg, J.; Boerjesson, S.; Larsson, E.M.; Gustafson, L.; Passant, U.; Staahlberg, F. [Depts. of Medical Radiation Physics, Diagnostic Radiology, Psychiatry, and Psychogeriatrics, Lund Univ, Lund (Sweden)

    2007-07-15

    Background: Attempts to retrieve absolute values of cerebral blood flow (CBF) by dynamic susceptibility contrast magnetic resonance imaging (DSC-MRI) have typically resulted in overestimations. Purpose: To improve DSC-MRI CBF estimates by calibrating the DSC-MRI-based cerebral blood volume (CBV) with a corresponding T1-weighted (T1W) steady-state (ss) CBV estimate. Material and Methods: 17 volunteers were investigated by DSC-MRI and 133Xe SPECT. Steady-state CBV calculation, assuming no water exchange, was accomplished using signal values from blood and tissue, before and after contrast agent, obtained by T1W spin-echo imaging. Using steady-state and DSC-MRI CBV estimates, a calibration factor K = CBV(ss)/CBV(DSC) was obtained for each individual. Average whole-brain CBF(DSC) was calculated, and the corrected MRI-based CBF estimate was given by CBF(ss) = KxCBF(DSC). Results: Average whole-brain SPECT CBF was 40.1{+-}6.9 ml/min 100 g, while the corresponding uncorrected DSC-MRI-based value was 69.2{+-}13.8 ml/mi 100 g. After correction with the calibration factor, a CBF(ss) of 42.7{+-}14.0 ml/min 100 g was obtained. The linear fit to CBF(ss)-versus-CBF(SPECT) data was close to proportionality (R = 0.52). Conclusion: Calibration by steady-state CBV reduced the population average CBF to a reasonable level, and a modest linear correlation with the reference 133Xe SPECT technique was observed. Possible explanations for the limited accuracy are, for example, large-vessel partial-volume effects, low post-contrast signal enhancement in T1W images, and water-exchange effects.

  19. Additive manufacturing of glass for optical applications

    Science.gov (United States)

    Luo, Junjie; Gilbert, Luke J.; Bristow, Douglas A.; Landers, Robert G.; Goldstein, Jonathan T.; Urbas, Augustine M.; Kinzel, Edward C.

    2016-04-01

    Glasses including fused quartz have significant scientific and engineering applications including optics, communications, electronics, and hermetic seals. This paper investigates a filament fed process for Additive Manufacturing (AM) of fused quartz. Additive manufacturing has several potential benefits including increased design freedom, faster prototyping, and lower processing costs for small production volumes. However, current research in AM of glasses is limited and has focused on non-optical applications. Fused quartz is studied here because of its desirability for high-quality optics due to its high transmissivity and thermal stability. Fused quartz also has a higher working temperature than soda lime glass which poses a challenge for AM. In this work, fused quartz filaments are fed into a CO2 laser generated melt pool, smoothly depositing material onto the work piece. Single tracks are printed to explore the effects that different process parameters have on the morphology of printed fused quartz. A spectrometer is used to measure the thermal radiation incandescently emitted from the melt pool. Thin-walls are printed to study the effects of layer-to-layer height. Finally, a 3D fused quartz cube is printed using the newly acquired layer height and polished on each surface. The transmittance and index homogeneity of the polished cube are both measured. These results show that the filament fed process has the potential to print fused quartz with optical transparency and of index of refraction uniformity approaching bulk processed glass.

  20. The Case for a New Approach to Sex Education Mounts; Will Policymakers Heed the Message? Guttmacher Policy Review. Volume 10, Number 2, Spring 2007

    Science.gov (United States)

    Boonstra, Heather D.

    2007-01-01

    Abstinence-only-until-marriage education is a key component of social conservatives' global moral and religious agenda, and the cornerstone of the Bush administration's approach to reducing U.S. teen pregnancy and sexually transmitted infection (STI) rates. Fearful of being portrayed as anti-abstinence, policymakers have continued to support these…

  1. Analysis and Approach to the Development of an Advanced Multimedia Instructional System. Volume II. Appendix III. Media Cost Data. Final Report.

    Science.gov (United States)

    Rhode, William E.; And Others

    Basic cost estimates for selected instructional media are tabled in this document, Part II (Appendix III) of the report "Analysis and Approach to the Development of an Advanced Multimedia Instructional System" by William E. Rhode and others. Learning materials production costs are given for motion pictures, still visuals, videotapes, live…

  2. Using a Data Mining Approach to Develop a Student Engagement-Based Institutional Typology. IR Applications, Volume 18, February 8, 2009

    Science.gov (United States)

    Luan, Jing; Zhao, Chun-Mei; Hayek, John C.

    2009-01-01

    Data mining provides both systematic and systemic ways to detect patterns of student engagement among students at hundreds of institutions. Using traditional statistical techniques alone, the task would be significantly difficult--if not impossible--considering the size and complexity in both data and analytical approaches necessary for this…

  3. Reading the World, the Globe, and the Cosmos: Approaches to Teaching Literature for the Twenty-First Century. Global Studies in Education. Volume 28

    Science.gov (United States)

    Choo, Suzanne S.

    2013-01-01

    The purpose of this book is restore the centrality of pedagogy in governing the ways literary texts are received, experienced, and interpreted by students in the classroom. Utilizing a method of pedagogical criticism, it provides an account of core approaches to teaching literature that have emerged across history and the conceptual values…

  4. Joint Precision Approach and Landing System Nunn-McCurdy Breach Root Cause Analysis and Portfolio Assessment Metrics for DoD Weapons Systems. Volume 8

    Science.gov (United States)

    2015-01-01

    career , he oversaw Army acquisition during a time of war and change. General Bolton was an admired mentor to many pilots and military acquisition...civil standard for precision approach and land- ing. The FAA was indecisive regarding the future of ILS because it changed the ILS drawdown multiple

  5. Addition on a Quantum Computer

    CERN Document Server

    Draper, Thomas G

    2000-01-01

    A new method for computing sums on a quantum computer is introduced. This technique uses the quantum Fourier transform and reduces the number of qubits necessary for addition by removing the need for temporary carry bits. This approach also allows the addition of a classical number to a quantum superposition without encoding the classical number in the quantum register. This method also allows for massive parallelization in its execution.

  6. Volume estimation in a sequence of freehand ultrasound images

    Science.gov (United States)

    Zhang, Hongmei; Wan, Mingxi; Shen, Bo; Wang, Xiaodong; Lu, Mingzhu

    2006-11-01

    Volume estimation is particularly important in clinical medicine. Accurate volume estimation can provide quantitative information from which the follow-up therapy can be derived. In this paper, an efficient approach to volume estimation in a sequence of freehand ultrasound images is proposed. By integral of vector areas along the path of centroids of serial cross-sections, 3D volume estimation can be represented as 2D area calculation, where a fast mapping algorithm generating 2D representation is presented so that the position of interpolation points can be calculated with high efficiency. Meanwhile, to improve the accuracy, the cubic spline with second-order continuity is proposed for interpolation of 2D representation. Volume estimation on simulating phantoms for parallel cutting, fan cutting and random cuttings is provided. The experimental results show that the 2D representation generated by the fast mapping algorithm is highly efficient with less than 0.001 ms for 100 cross-sections. Quantitative comparisons show that the proposed interpolation method can approximate the original volume more precisely as compared to the Catmull-Rom (CR) spline, especially in the case of small number of cross-sections. In all cases, our approach can obtain accurate results at an error of less than 2% for ten cross-sections. Additionally, volume estimation on a high intensity focused ultrasound (HIFU) lesion based on linear B-scan and rotational B-scan sequential images are also performed. The experiments show that the proposed approach is promising and may have potential in clinical applications.

  7. The large-volume high-pressure facility at GSECARS: A 'Swiss-army-knife' approach to synchrotron-based experimental studies

    Energy Technology Data Exchange (ETDEWEB)

    Wang, Yanbin; Rivers, Mark; Sutton, Steve; Nishiyama, Norimasa; Uchida, Takeyuki; Sanehira, Takeshi; (UC)

    2009-06-01

    A number of new techniques have been developed at the large-volume press (LVP) high-pressure facility at the GeoSoilEnviroCARS (GSECARS) sector of the advanced photon source (APS). This article describes the 10 MN (1000 T) and 2.5 MN (250 T) hydraulic presses in the insertion device (ID) and bending magnet (BM) beamlines, respectively, with several apparatus and various diffraction and imaging techniques developed since the inception of the facility. Several Kawai-type high-pressure modules, whose second-stage anvils range from 10 mm to 25.4 mm in edge lengths, are used in the hydraulic presses, with pressure (P) and temperature (T) capabilities up to 30 GPa and 3000 K. A DIA-type apparatus can be compressed in both presses for studies requiring large sample volumes. A deformation DIA (D-DIA) has been developed to allow controlled deformation studies on both crystalline and glass materials, using monochromatic diffraction and imaging, up to 20 GPa and 1800 K. A high-pressure tomography apparatus is available for conducting tomography studies at high P and T, with a typical spatial resolution of a few micrometers. Toroidal anvil modules provide large 2{theta} angles for studies of non-crystalline materials, and a new large D-DIA module is under construction for double-stage megabar pressure generation as well as deformation on large samples with the capability of acoustic emission detection. The flexible design of the monochromator at the BM beamline makes it feasible to switch between monochromatic and white-beam mode during an experiment, ideal for monochromatic imaging studies (e.g., high-P tomography) with energy-dispersive diffraction for pressure measurements. A new angle-dispersive diffraction technique has been developed for high P-T crystallography studies, where a solid-state detector is step-scanned, thereby collecting a large number of angle-dispersive spectra over a wide range of photon energies recorded in the multi-channel analyzer. An ultrasonic

  8. Comparing Volumes of Prisms and Pyramids

    Science.gov (United States)

    Vinogradova, Natalya

    2012-01-01

    Students' experience in using formulas for volumes is often limited to substituting numbers into given formulas. An activity presented in this article may help students make connections between the formulas for volumes of prisms and volumes of pyramids. In addition, some interesting facts from number theory arise, demonstrating strong connections…

  9. Physical activity over a decade modifies age-related decline in perfusion, gray matter volume, and functional connectivity of the posterior default mode network : a multimodal approach

    OpenAIRE

    Boraxbekk, Carl-Johan; Salami, Alireza; Wåhlin, Anders; Nyberg, Lars

    2016-01-01

    One step toward healthy brain aging may be to entertain a physically active lifestyle. Studies investigating physical activity effects on brain integrity have, however, mainly been based on single brain markers, and few used a multimodal imaging approach. In the present study, we used cohort data from the Betula study to examine the relationships between scores reflecting current and accumulated physical activity and brain health. More specifically, we first examined if physical activity scor...

  10. A Well-Clear Volume Based on Time to Entry Point

    Science.gov (United States)

    Narkawicz, Anthony J.; Munoz, Cesar A.; Upchurch, Jason M.; Chamberlain, James P.; Consiglio, Maria C.

    2014-01-01

    A well-clear volume is a key component of NASA's Separation Assurance concept for the integration of UAS in the NAS. This paper proposes a mathematical definition of the well-clear volume that uses, in addition to distance thresholds, a time threshold based on time to entry point (TEP). The mathematical model that results from this definition is more conservative than other candidate definitions of the wellclear volume that are based on range over closure rate and time to closest point of approach.

  11. A finite volume approach to the problem of heat transfer in axisymmetric annulus geometry with internal heating element using local analytical solution techniques

    Energy Technology Data Exchange (ETDEWEB)

    Salama, A. [Atomic Energy Authority (AEA), Cairo (Egypt). Nuclear Research Center

    2014-11-15

    In this paper we implement the local analytical solution technique to the problem of heat transfer in axisymmetric annulus geometry with internal heating element. This method has shown to be very accurate in estimating the temperature field for axisymmetric problems even for coarse mesh. It is shown that this method reduces to the analytical solution for unidirectional heat transfer in the radial direction in homogeneous media. The technique is based on finding an analytical expression for the temperature field in the radial direction within each grid cell. This means that the temperature field in each cell is allowed to change in a nonlinear fashion along the radial direction. We compare this technique with the traditional finite volume technique and show that; with only few cells in the radial direction, this technique arrives at the mesh-independent solution quite accurately whereas it required denser mesh to arrive closer to this solution using traditional techniques. This method is proposed to the 1D codes that are currently being used to simulate thermalhydraulic characteristics of reactor systems. Furthermore, we also implement the experimental temperature field algorithm in which the governing equations are approximated for each cell as it would without extra manipulation to the governing equations. This technique is very simple and separates the physics from the solving part.

  12. Parametric approaches to micro-scale characterization of tissue volumes in vivo and ex vivo: Imaging microvasculature, attenuation, birefringence, and stiffness (Conference Presentation)

    Science.gov (United States)

    Sampson, David D.; Chin, Lixin; Gong, Peijun; Wijesinghe, Philip; Es'haghian, Shaghayegh; Allen, Wesley M.; Klyen, Blake R.; Kirk, Rodney W.; Kennedy, Brendan F.; McLaughlin, Robert A.

    2016-03-01

    INVITED TALK Advances in imaging tissue microstructure in living subjects, or in freshly excised tissue with minimum preparation and processing, are important for future diagnosis and surgical guidance in the clinical setting, particularly for application to cancer. Whilst microscopy methods continue to advance on the cellular scale and medical imaging is well established on the scale of the whole tumor or organ, it is attractive to consider imaging the tumor environment on the micro-scale, between that of cells and whole tissues. Such a scenario is ideally suited to optical coherence tomography (OCT), with the twin attractions of requiring little or no tissue preparation, and in vivo capability. OCT's intrinsic scattering contrast reveals many morphological features of tumors, but is frequently ineffective in revealing other important aspects, such as microvasculature, or in reliably distinguishing tumor from uninvolved stroma. To address these shortcomings, we are developing several advances on the basic OCT approach. We are exploring speckle fluctuations to image tissue microvasculature and we have been developing several parametric approaches to tissue micro-scale characterization. Our approaches extract, from a three-dimensional OCT data set, a two-dimensional image of an optical parameter, such as attenuation or birefringence, or a mechanical parameter, such as stiffness, that aids in characterizing the tissue. This latter method, termed optical coherence elastography, parallels developments in ultrasound and magnetic resonance imaging. Parametric imaging of birefringence and of stiffness both show promise in addressing the important issue of differentiating cancer from uninvolved stroma in breast tissue.

  13. Risk-based approach to developing a national residue sampling plan for testing under European Union regulation for veterinary medicinal products and coccidiostat feed additives in domestic animal production.

    Science.gov (United States)

    Danaher, Martin; Shanahan, Conor; Butler, Francis; Evans, Rhodri; O'Sullivan, Dan; Glynn, Denise; Camon, Tim; Lawlor, Peadar; O'Keeffe, Michael

    2016-07-01

    A ranking system for veterinary medicinal products and coccidiostat feed additives has been developed as a tool to be applied in a risk-based approach to the residue testing programme for foods of animal origin in the Irish National Residue Control Plan (NRCP). Three characteristics of substances that may occur as residues in food are included in the developed risk ranking system: Potency, as measured by the acceptable daily intake assigned by the European Medicines Agency Committee for Medicinal Products for Veterinary Use, to each substance; Usage, as measured by the three factors of Number of Doses, use on Individual animals or for Group treatment, and Withdrawal Period; and Residue Occurrence, as measured by the number of Non-Compliant Samples in the NRCP. For both Number of Doses and Non-Compliant Samples, data for the 5-year period 2008-12 have been used. The risk ranking system for substances was developed for beef cattle, sheep and goats, pigs, chickens and dairy cattle using a scoring system applied to the various parameters described above to give an overall score based on the following equation: Potency × Usage (Number of Doses + Individual/Group Use + Withdrawal Period) × Residue Occurrence. Applying this risk ranking system, the following substances are ranked very highly: antimicrobials such as amoxicillin (for all species except pigs), marbofloxacillin (for beef cattle), oxytetracycline (for all species except chickens), sulfadiazine with trimethoprim (for pigs and chickens) and tilmicosin (for chickens); antiparasitic drugs, such as the benzimidazoles triclabendazole (for beef and dairy cattle), fenbendazole/oxfendazole (for sheep/goats and dairy cattle) and albendazole (for dairy cattle), the avermectin ivermectin (for beef cattle), and anti-fluke drugs closantel and rafoxanide (for sheep/goats); the anticoccidials monensin, narasin, nicarbazin and toltrazuril (for chickens). The risk ranking system described is a relatively simple system

  14. Preliminary design study of underground pumped hydro and compressed-air energy storage in hard rock. Volume 8: Design approaches: UPH

    Science.gov (United States)

    1981-06-01

    The development of the design approaches used to determine the plant and overall layout for a underground pumped hydroelectric (UPH) storage facility having a maximum generating capacity of 2000 MW and a storage capacity of 20,000 MWh is discussed. Key factors were the selection of the high head pump-turbine equipment and the geotechnical considerations relevant to the underground cavern designs. The comparison of pump-turbine alternatives is described leading to the selection for detailed study of both a single-step configurations, using multistage reversible pump-turbines, and a two-step configuration, with single-stage reversible pump-turbines.

  15. Renormalized Volume

    CERN Document Server

    Gover, A Rod

    2016-01-01

    For any conformally compact manifold with hypersurface boundary we define a canonical renormalized volume functional and compute an explicit, holographic formula for the corresponding anomaly. For the special case of asymptotically Einstein manifolds, our method recovers the known results. The anomaly does not depend on any particular choice of regulator, but the coefficients of divergences do. We give explicit formulae for these divergences valid for any choice of regulating hypersurface; these should be relevant to recent studies of quantum corrections to entanglement entropies. The anomaly is expressed as a conformally invariant integral of a local Q-curvature that generalizes the Branson Q-curvature by including data of the embedding. In each dimension this canonically defines a higher dimensional generalization of the Willmore energy/rigid string action. We show that the variation of these energy functionals is exactly the obstruction to solving a singular Yamabe type problem with boundary data along the...

  16. Aperiodic Volume Optics

    Science.gov (United States)

    Gerke, Tim D.

    periodic and quasi-periodic systems for the manipulation of light in the IR regime. The general thesis of this document is that aperiodic three-dimensional structures provide additional degrees of freedom that can be utilized to improve on the performance of periodic volume devices. The results we will discuss suggest that, under certain circumstances, a departure from the Bragg paradigm provides enhanced volume diffraction properties.

  17. Biochemical kinetics in changing volumes.

    Science.gov (United States)

    Pawłowski, Piotr H; Zielenkiewicz, Piotr

    2004-01-01

    The need of taking into account the change of compartment volume when developing chemical kinetics analysis inside the living cell is discussed. Literature models of a single enzymatic Michaelis-Menten process, glycolytic oscillations, and mitotic cyclin oscillations were tested with appropriate theoretical extension in the direction of volume modification allowance. Linear and exponential type of volume increase regimes were compared. Due to the above, in a growing cell damping of the amplitude, phase shift, and time pattern deformation of the metabolic rhythms considered were detected, depending on the volume change character. The performed computer simulations allow us to conclude that evolution of the cell volume can be an essential factor of the chemical kinetics in a growing cell. The phenomenon of additional metabolite oscillations caused by the periodic cell growth and division was theoretically predicted and mathematically described. Also, the hypothesis of the periodized state in the growing cell as the generalization of the steady-state was formulated.

  18. An approach to the verification of a fault-tolerant, computer-based reactor safety system: A case study using automated reasoning: Volume 1: Interim report

    Energy Technology Data Exchange (ETDEWEB)

    Chisholm, G.H.; Kljaich, J.; Smith, B.T.; Wojcik, A.S.

    1987-01-01

    The purpose of this project is to explore the feasibility of automating the verification process for computer systems. The intent is to demonstrate that both the software and hardware that comprise the system meet specified availability and reliability criteria, that is, total design analysis. The approach to automation is based upon the use of Automated Reasoning Software developed at Argonne National Laboratory. This approach is herein referred to as formal analysis and is based on previous work on the formal verification of digital hardware designs. Formal analysis represents a rigorous evaluation which is appropriate for system acceptance in critical applications, such as a Reactor Safety System (RSS). This report describes a formal analysis technique in the context of a case study, that is, demonstrates the feasibility of applying formal analysis via application. The case study described is based on the Reactor Safety System (RSS) for the Experimental Breeder Reactor-II (EBR-II). This is a system where high reliability and availability are tantamount to safety. The conceptual design for this case study incorporates a Fault-Tolerant Processor (FTP) for the computer environment. An FTP is a computer which has the ability to produce correct results even in the presence of any single fault. This technology was selected as it provides a computer-based equivalent to the traditional analog based RSSs. This provides a more conservative design constraint than that imposed by the IEEE Standard, Criteria For Protection Systems For Nuclear Power Generating Stations (ANSI N42.7-1972).

  19. An approach to the verification of a fault-tolerant, computer-based reactor safety system: A case study using automated reasoning: Volume 2, Appendixes: Interim report

    Energy Technology Data Exchange (ETDEWEB)

    Chisholm, G.H.; Kljaich, J.; Smith, B.T.; Wojcik, A.S.

    1987-01-01

    The purpose of this project is to explore the feasibility of automating the verification process for computer systems. The intent is to demonstrate that both the software and hardware that comprise the system meet specified availability and reliability criteria, that is, total design analysis. The approach to automation is based upon the use of Automated Reasoning Software developed at Argonne National Laboratory. This approach is herein referred to as formal analysis and is based on previous work on the formal verification of digital hardware designs. Formal analysis represents a rigorous evaluation which is appropriate for system acceptance in critical applications, such as a Reactor Safety System (RSS). This report describes a formal analysis technique in the context of a case study, that is, demonstrates the feasibility of applying formal analysis via application. The case study described is based on the Reactor Safety System (RSS) for the Experimental Breeder Reactor-II (EBR-II). This is a system where high reliability and availability are tantamount to safety. The conceptual design for this case study incorporates a Fault-Tolerant Processor (FTP) for the computer environment. An FTP is a computer which has the ability to produce correct results even in the presence of any single fault. This technology was selected as it provides a computer-based equivalent to the traditional analog based RSSs. This provides a more conservative design constraint than that imposed by the IEEE Standard, Criteria For Protection Systems For Nuclear Power Generating Stations (ANSI N42.7-1972).

  20. Application of layout optimization to the design of additively manufactured metallic components

    OpenAIRE

    Smith, C. J.; Gilbert, M.; Todd, I; Derguti, F.

    2016-01-01

    Additive manufacturing (‘3D printing’) techniques provide engineers with unprecedented design freedoms, opening up the possibility for stronger and lighter component designs. In this paper ‘layout optimization’ is used to provide a reference volume and to identify potential design topologies for a given component, providing a useful alternative to continuum based topology optimization approaches (which normally require labour intensive post-processing in order to realise a practical component...

  1. Human factors evaluation of remote afterloading brachytherapy: Human error and critical tasks in remote afterloading brachytherapy and approaches for improved system performance. Volume 1

    Energy Technology Data Exchange (ETDEWEB)

    Callan, J.R.; Kelly, R.T.; Quinn, M.L. [Pacific Science and Engineering Group, San Diego, CA (United States)] [and others

    1995-05-01

    Remote Afterloading Brachytherapy (RAB) is a medical process used in the treatment of cancer. RAB uses a computer-controlled device to remotely insert and remove radioactive sources close to a target (or tumor) in the body. Some RAB problems affecting the radiation dose to the patient have been reported and attributed to human error. To determine the root cause of human error in the RAB system, a human factors team visited 23 RAB treatment sites in the US The team observed RAB treatment planning and delivery, interviewed RAB personnel, and performed walk-throughs, during which staff demonstrated the procedures and practices used in performing RAB tasks. Factors leading to human error in the RAB system were identified. The impact of those factors on the performance of RAB was then evaluated and prioritized in terms of safety significance. Finally, the project identified and evaluated alternative approaches for resolving the safety significant problems related to human error.

  2. Food additives and preschool children.

    Science.gov (United States)

    Martyn, Danika M; McNulty, Breige A; Nugent, Anne P; Gibney, Michael J

    2013-02-01

    Food additives have been used throughout history to perform specific functions in foods. A comprehensive framework of legislation is in place within Europe to control the use of additives in the food supply and ensure they pose no risk to human health. Further to this, exposure assessments are regularly carried out to monitor population intakes and verify that intakes are not above acceptable levels (acceptable daily intakes). Young children may have a higher dietary exposure to chemicals than adults due to a combination of rapid growth rates and distinct food intake patterns. For this reason, exposure assessments are particularly important in this age group. The paper will review the use of additives and exposure assessment methods and examine factors that affect dietary exposure by young children. One of the most widely investigated unfavourable health effects associated with food additive intake in preschool-aged children are suggested adverse behavioural effects. Research that has examined this relationship has reported a variety of responses, with many noting an increase in hyperactivity as reported by parents but not when assessed using objective examiners. This review has examined the experimental approaches used in such studies and suggests that efforts are needed to standardise objective methods of measuring behaviour in preschool children. Further to this, a more holistic approach to examining food additive intakes by preschool children is advisable, where overall exposure is considered rather than focusing solely on behavioural effects and possibly examining intakes of food additives other than food colours.

  3. Disambiguating Stereoscopic Transparency Using a Thaumatrope Approach.

    Science.gov (United States)

    Yan-Jen Su; Yung-Yu Chuang

    2015-08-01

    Volume rendering is a popular visualization technique for scientific computing and medical imaging. By assigning proper transparency, it allows us to see more information inside the volume. However, because volume rendering projects complex 3D structures into the 2D domain, the resultant visualization often suffers from ambiguity and its spatial relationship could be difficult to recognize correctly, especially when the scene or setting is highly transparent. Stereoscopic displays are not the rescue to the problem even though they add an additional dimension which seems helpful for resolving the ambiguity. This paper proposes a thaumatrope method to enhance 3D understanding with stereoscopic transparency for volume rendering. Our method first generates an additional cue with less spatial ambiguity by using a high opacity setting. To avoid cluttering the actual content, we only select its prominent feature for displaying. By alternating the actual content and the selected feature quickly, the viewer only perceives a whole volume while its spatial understanding has been enhanced. A user study was performed to compare the proposed method with the original stereoscopic volume rendering and the static combination of the actual content and the selected feature using a 3D display. Results show that the proposed thaumatrope approach provides better spatial understanding than compared approaches.

  4. Characterization and Prediction of the Volume Flow Rate Aerating a Cross Ventilated Bilding by Means of Experimental Techniques and Numerical Approaches

    DEFF Research Database (Denmark)

    Larsen, Tine Steen; Nikolopoulos, N.; Nikolopoulos, A.

    2011-01-01

    anemometers across the openings, whilst the numerical methodology is based on the time-dependant solution of the governing Navier-Stokes equations. The experimental data are compared to the corresponding numerical results, revealing the unsteady character of the flow field especially at large incidence angles......The paper presents an extensive experimental and numerical study on a cross-ventilated building providing important features of the induced flow patterns at the two openings as a function of the free stream wind velocity’s magnitude and its incidence angle. The experimental data are measured via....... Furthermore, additional information regarding the flow field near the opening edges, not easily extracted by experimental methods, provide an in depth sight in the main characteristics of the flow field both at the openings but also inside the building. Finally, a new methodology for the approximation...

  5. [Food additives and healthiness].

    Science.gov (United States)

    Heinonen, Marina

    2014-01-01

    Additives are used for improving food structure or preventing its spoilage, for example. Many substances used as additives are also naturally present in food. The safety of additives is evaluated according to commonly agreed principles. If high concentrations of an additive cause adverse health effects for humans, a limit of acceptable daily intake (ADI) is set for it. An additive is a risk only when ADI is exceeded. The healthiness of food is measured on the basis of nutrient density and scientifically proven effects.

  6. Solid Oxide Fuel Cell APU Feasibility Study for a Long Range Commercial Aircraft Using UTC ITAPS Approach. Volume 1; Aircraft Propulsion and Subsystems Integration Evaluation

    Science.gov (United States)

    Srinivasan, Hari; Yamanis, Jean; Welch, Rick; Tulyani, Sonia; Hardin, Larry

    2006-01-01

    The objective of this contract effort was to define the functionality and evaluate the propulsion and power system benefits derived from a Solid Oxide Fuel Cell (SOFC) based Auxiliary Power Unit (APU) for a future long range commercial aircraft, and to define the technology gaps to enable such a system. The study employed technologies commensurate with Entry into Service (EIS) in 2015. United Technologies Corporation (UTC) Integrated Total Aircraft Power System (ITAPS) methodologies were used to evaluate system concepts to a conceptual level of fidelity. The technology benefits were captured as reductions of the mission fuel burn and emissions. The baseline aircraft considered was the Boeing 777-200ER airframe with more electric subsystems, Ultra Efficient Engine Technology (UEET) engines, and an advanced APU with ceramics for increased efficiency. In addition to the baseline architecture, four architectures using an SOFC system to replace the conventional APU were investigated. The mission fuel burn savings for Architecture-A, which has minimal system integration, is 0.16 percent. Architecture-B and Architecture-C employ greater system integration and obtain fuel burn benefits of 0.44 and 0.70 percent, respectively. Architecture-D represents the highest level of integration and obtains a benefit of 0.77 percent.

  7. Surface and Volume Grid Generation in Parametric Form

    Science.gov (United States)

    Yu, Tzuyi; Soni, Bharat K.; Benjamin, Ted; Williams, Robert

    1996-01-01

    The algorithm for surface modeling and volume grid generation using parametric Non-Uniform Rational B-splines (NURBS) geometric representation are presented. The enhanced re-parameterization algorithm which can yield a desired physical distribution on the curve, surface, and volume is also presented. This approach bridges the gap between computer aided design surface/volume definition and surface/volume grid generation.

  8. Additives in yoghurt production

    Directory of Open Access Journals (Sweden)

    Milna Tudor

    2008-02-01

    Full Text Available In yoghurt production, mainly because of sensory characteristics, different types of additives are used. Each group, and also each substance from the same group has different characteristics and properties. For that reason, for improvement of yoghurt sensory characteristics apart from addition selection, the quantity of the additive is very important. The same substance added in optimal amount improves yoghurt sensory attributes, but too small or too big addition can reduce yoghurt sensory attributes. In this paper, characteristics and properties of mostly used additives in yoghurt production are described; skimmed milk powder, whey powder, concentrated whey powder, sugars and artificial sweeteners, fruits, stabilizers, casein powder, inulin and vitamins. Also the impact of each additive on sensory and physical properties of yoghurt, syneresis and viscosity, are described, depending on used amount added in yoghurt production.

  9. Wire + Arc Additive Manufacturing

    OpenAIRE

    Williams, Stewart W.; Martina, Filomeno; Addison, Adrian C.; Ding, Jialuo; Pardal, Goncalo; Colegrove, Paul A.

    2016-01-01

    Depositing large components (>10 kg) in titanium, aluminium, steel and other metals is possible using Wire + Arc Additive Manufacturing. This technology adopts arc welding tools and wire as feedstock for additive manufacturing purposes. High deposition rates, low material and equipment costs, and good structural integrity make Wire+Arc Additive Manufacturing a suitable candidate for replacing the current method of manufacturing from solid billets or large forgings, especially with regards to ...

  10. Additive Manufactured Product Integrity

    Science.gov (United States)

    Waller, Jess; Wells, Doug; James, Steve; Nichols, Charles

    2017-01-01

    NASA is providing key leadership in an international effort linking NASA and non-NASA resources to speed adoption of additive manufacturing (AM) to meet NASA's mission goals. Participants include industry, NASA's space partners, other government agencies, standards organizations and academia. Nondestructive Evaluation (NDE) is identified as a universal need for all aspects of additive manufacturing.

  11. Polylactides in additive biomanufacturing.

    Science.gov (United States)

    Poh, Patrina S P; Chhaya, Mohit P; Wunner, Felix M; De-Juan-Pardo, Elena M; Schilling, Arndt F; Schantz, Jan-Thorsten; van Griensven, Martijn; Hutmacher, Dietmar W

    2016-12-15

    New advanced manufacturing technologies under the alias of additive biomanufacturing allow the design and fabrication of a range of products from pre-operative models, cutting guides and medical devices to scaffolds. The process of printing in 3 dimensions of cells, extracellular matrix (ECM) and biomaterials (bioinks, powders, etc.) to generate in vitro and/or in vivo tissue analogue structures has been termed bioprinting. To further advance in additive biomanufacturing, there are many aspects that we can learn from the wider additive manufacturing (AM) industry, which have progressed tremendously since its introduction into the manufacturing sector. First, this review gives an overview of additive manufacturing and both industry and academia efforts in addressing specific challenges in the AM technologies to drive toward AM-enabled industrial revolution. After which, considerations of poly(lactides) as a biomaterial in additive biomanufacturing are discussed. Challenges in wider additive biomanufacturing field are discussed in terms of (a) biomaterials; (b) computer-aided design, engineering and manufacturing; (c) AM and additive biomanufacturing printers hardware; and (d) system integration. Finally, the outlook for additive biomanufacturing was discussed. Copyright © 2016 Elsevier B.V. All rights reserved.

  12. Minivoids in the Local Volume

    CERN Document Server

    Tikhonov, A V

    2006-01-01

    We consider a sphere of 7.5 Mpc radius, which contains 355 galaxies with accurately measured distances, to detect the nearest empty volumes. Using a simple void detection algorithm, we found six large (mini)voids in Aquila, Eridanus, Leo, Vela, Cepheus and Octans, each of more than 30 Mpc^3. Besides them, 24 middle-size "bubbles" of more than 5 Mpc^3 volume are detected, as well as 52 small "pores". The six largest minivoids occupy 58% of the considered volume. Addition of the bubbles and pores to them increases the total empty volume up to 75% and 81%, respectively. The detected local voids look like oblong potatoes with typical axial ratios b/a = 0.75 and c/a = 0.62 (in the triaxial ellipsoide approximation). Being arranged by the size of their volume, local voids follow power law of volumes-rankes dependence. A correlation Gamma-function of the Local Volume galaxies follows a power low with a formally calculated fractal dimension D = 1.5. We found that galaxies surrounding the local minivoids do not differ...

  13. Additive Gaussian Processes

    CERN Document Server

    Duvenaud, David; Rasmussen, Carl Edward

    2011-01-01

    We introduce a Gaussian process model of functions which are additive. An additive function is one which decomposes into a sum of low-dimensional functions, each depending on only a subset of the input variables. Additive GPs generalize both Generalized Additive Models, and the standard GP models which use squared-exponential kernels. Hyperparameter learning in this model can be seen as Bayesian Hierarchical Kernel Learning (HKL). We introduce an expressive but tractable parameterization of the kernel function, which allows efficient evaluation of all input interaction terms, whose number is exponential in the input dimension. The additional structure discoverable by this model results in increased interpretability, as well as state-of-the-art predictive power in regression tasks.

  14. Additive and polynomial representations

    CERN Document Server

    Krantz, David H; Suppes, Patrick

    1971-01-01

    Additive and Polynomial Representations deals with major representation theorems in which the qualitative structure is reflected as some polynomial function of one or more numerical functions defined on the basic entities. Examples are additive expressions of a single measure (such as the probability of disjoint events being the sum of their probabilities), and additive expressions of two measures (such as the logarithm of momentum being the sum of log mass and log velocity terms). The book describes the three basic procedures of fundamental measurement as the mathematical pivot, as the utiliz

  15. 浅析2010年版《中国药典》(一部)增修订情况及其临床指导意义%Analysis of the Additional and Revised Description of 2010 Edition of Chinese Pharmacopoeia(Volume Ⅰ) and Its Clinical Guiding Significance

    Institute of Scientific and Technical Information of China (English)

    张碧华; 高素强; 傅得兴

    2013-01-01

    OBJECTIVE:To sum up the additional and revised description of 2010 edition of Chinese Pharmacopoeia(volume Ⅰ),and to discuss its guiding significance for clinical rational drug use.METHODS:2010 edition of Chinese Pharmacopoeia(volume Ⅰ) was compared with different editions chinese pharmaiopoeias,The characteristic of addtion and revision in volume 1 of Chinese Pharmacopeia as well as TCM decoction piece were summed up.RESULTS:There were 2 165 varieties recorded in the Chinese Pharmacopoeia,among which 1 019 varieties were new added (including 439 decoction pieces standards) and 634 varieties were revised.Recorded species,decoction pieces standard was increased significantly,drug standard was more reasonable,and drug safety was stronger,new detection techniques and methods was adopted and appendix of the standard was further improved.Latin names,medicinal parts,indications of the function,dosage,route of administration and attention of many herbs had been revised.CONCLUSIONS:2010 edition of Chinese Pharmacopoeia embody the development level of the drug check in China and the character of clinical drug use,furthermore which make great development in the security and controllability of drug administration.So it should exert the positive effect among improving quality of TCM decoction pieces and Chinese patent medicine,ensuring safety and efficiency of clinical drug use and regulating the development of TCM industry.%目的:了解2010年版《中国药典》(一部)增修订情况,探讨其对于临床用药的指导意义.方法:将2010年版《中国药典》(一部)与历版《中国药典》进行对比,总结新版增、修订特点,以及药材饮片增、修订情况.结果:2010年版《中国药典》(一部)共收载品种2 165个,新增品种1 019个(包括439个饮片标准),修订634种;收载品种、饮片标准大幅增加,药品标准更为合理,药品安全性更强,加入了新的检测技术和方法,附录更完善;许多药材的拉丁名

  16. Groups – Additive Notation

    Directory of Open Access Journals (Sweden)

    Coghetto Roland

    2015-06-01

    Full Text Available We translate the articles covering group theory already available in the Mizar Mathematical Library from multiplicative into additive notation. We adapt the works of Wojciech A. Trybulec [41, 42, 43] and Artur Korniłowicz [25].

  17. Food Additives and Hyperkinesis

    Science.gov (United States)

    Wender, Ester H.

    1977-01-01

    The hypothesis that food additives are causally associated with hyperkinesis and learning disabilities in children is reviewed, and available data are summarized. Available from: American Medical Association 535 North Dearborn Street Chicago, Illinois 60610. (JG)

  18. Additively Manufactured Propulsion System

    OpenAIRE

    Dushku, Matthew; Mueller, Paul

    2012-01-01

    New high-performance, carbon-fiber reinforced polymer material allows additive manufacturing to produce pressure vessels capable of high pressures (thousands of pounds per square inch). This advancement in turn allows integral hybrid propulsion which is revolutionary for both CubeSats and additively-manufactured spacecraft. Hybrid propulsion offers simplicity as compared to bipropellant liquid propulsion, significantly better safety compared to solid or monopropellant hydrazine propulsion, an...

  19. Culture of Schools. Final Report. Volume I.

    Science.gov (United States)

    American Anthropological Association, Washington, DC.

    The first volume of this 4-volume report presents the basic rationale for an anthropological and cross-cultural approach to education, abstracts of 14 research projects sponsored by the American Anthropological Association, a proposal for the establishment of a Research Center for Anthropology and Education to be coordinated by the Association, a…

  20. Volume of a doubly truncated hyperbolic tetrahedron

    CERN Document Server

    Kolpakov, Alexander

    2012-01-01

    The present paper regards the volume function of a doubly truncated hyperbolic tetrahedron. Starting from the previous results of J. Murakami, U. Yano and A. Ushijima, we have developed a unified approach to expressing the volume in different geometric cases by dilogarithm functions and to treat properly the many analytic strata of the latter. Finally, several numeric examples are given.

  1. Lake volume monitoring from space

    Science.gov (United States)

    Crétaux, Jean-Francois; Abarca Del Rio, Rodrigo; Berge-Nguyen, Muriel; Arsen, Adalbert; Drolon, Vanessa; Maisongrande, Philippe

    2016-04-01

    Lakes are integrator of environmental changes occurring at regional to global scale and present a high variety of behaviors on a variety of time scales (cyclic and secular) depending on the climate conditions and their morphology. In addition their crucial importance as water stocks and retaining, given the significant environment changes occurring worldwide at many anthropocentric levels, has increased the necessity of monitoring all its morphodynamics characteristics, say water level, surface (water contour) and volume. The satellite altimetry and satellite imagery together are now widely used for the calculation of lakes and reservoirs water storage changes worldwide. However strategies and algorithms to calculate these characteristics are not straightforward and need development of specific approaches. We intend to present a review of some of these methodologies by using the lakes over the Tibetan Plateau to illustrate some critical aspects and issues (technical and scientific) linked with the survey of climate changes impacts on surface waters from remote sensing data. Many authors have measured water variations using the short period of remote sensing measurements available, although time series are probably too short to lead to definitive conclusions to link these results directly with the framework of climate changes. Indeed, many processes beyond the observations are still uncertain, for example the influence of morphology of the lakes. The time response for a lake to reach new state of equilibrium is one of the key aspects often neglected in the current literature. Observations over long period of time, therein maintaining a constellation of comprehensive and complementary satellite missions with a continuity of services over decades, especially when ground gauges network is too limited is therefore a necessity. In addition, the design of future satellite missions with new instrumental concepts (e.g. SAR, SARin, Ka band altimetry, Ka interferometry) is

  2. Fine-grained concrete with organomineral additive

    Directory of Open Access Journals (Sweden)

    Solovyov Vitaly

    2016-01-01

    Full Text Available The article deals with the issues concerning the formation of the structure and properties of fine-grained concrete with organomineral additive produced through mechanochemical activation of thermal power plant fly ash together with superplasticizer. The additive is produced in a high-speed activator at the collision particles’ speed of about 80 m/s. The use of the additive in fine-grained concrete in the amounts of 0.5-1% increased the strength by 30-50% and reduced the size and volume of pores. The cement consumption in such concrete is close to the cement consumption in common concrete of equal resistance.

  3. Additive Manufacturing Infrared Inspection

    Science.gov (United States)

    Gaddy, Darrell

    2014-01-01

    Additive manufacturing is a rapid prototyping technology that allows parts to be built in a series of thin layers from plastic, ceramics, and metallics. Metallic additive manufacturing is an emerging form of rapid prototyping that allows complex structures to be built using various metallic powders. Significant time and cost savings have also been observed using the metallic additive manufacturing compared with traditional techniques. Development of the metallic additive manufacturing technology has advanced significantly over the last decade, although many of the techniques to inspect parts made from these processes have not advanced significantly or have limitations. Several external geometry inspection techniques exist such as Coordinate Measurement Machines (CMM), Laser Scanners, Structured Light Scanning Systems, or even traditional calipers and gages. All of the aforementioned techniques are limited to external geometry and contours or must use a contact probe to inspect limited internal dimensions. This presentation will document the development of a process for real-time dimensional inspection technique and digital quality record of the additive manufacturing process using Infrared camera imaging and processing techniques.

  4. Alternative additives; Alternative additiver

    Energy Technology Data Exchange (ETDEWEB)

    2007-08-15

    In this project a number of industrial and agricultural waste products have been characterised and evaluated in terms of alkali-getter performance. The intended use is for biomass-fired power stations aiming at reducing corrosion or slagging related problems. The following products have been obtained, characterised and evaluated: 1) Brewery draff 2) Danish de-gassed manure 3) Paper sludge 4) Moulding sand 5) Spent bleaching earth 6) Anorthosite 7) Sand 8) Clay-sludge. Most of the above alternative additive candidates are deemed unsuitable due to insufficient chemical effect and/or expensive requirements for pre-treatment (such as drying and transportation). 3 products were selected for full-scale testing: de-gassed manure, spent bleaching earth and clay slugde. The full scale tests were undertaken at the biomass-fired power stations in Koege, Slagelse and Ensted. Spent bleaching earth (SBE) and clay sludge were the only tested additive candidates that had a proven ability to react with KCl, to thereby reduce Cl-concentrations in deposits, and reduce the deposit flux to superheater tubes. Their performance was shown to nearly as good as commercial additives. De-gassed manure, however, did not evaluate positively due to inhibiting effects of Ca in the manure. Furthermore, de-gassed manure has a high concentration of heavy metals, which imposes a financial burden with regard to proper disposal of the ash by-products. Clay-sludge is a wet clay slurring, and drying and transportation of this product entails substantial costs. Spent bleaching does not require much pre-treatment and is therefore the most promising alternative additive. On the other hand, bleaching earth contains residual plant oil which means that a range of legislation relating to waste combustion comes into play. Not least a waste combustion fee of 330 DKK/tonne. For all alternative (and commercial) additives disposal costs of the increase ash by-products represents a significant cost. This is

  5. Additives for the Axe

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    On May 1,China will begin to ban the production and use of two food additives commonly used to "bleach" flour,benzoyl peroxide and calcium peroxide.The decision was made after 10 years of wrangling between the policy makers,manufacturers,scientists and consumers.The Ministry of Health said in a statement it was applying the ban in response to consumers’ concerns about chemical substances in food,and technical improvements that had made the two additives unnecessary in flour processing.Minister of Health Chen Zhu has also said

  6. Alcohols as gasoline additives

    Energy Technology Data Exchange (ETDEWEB)

    Jawetz, P.

    1982-12-01

    This paper showed that, when using alcohol octane-boosting additives to gasoline, one attains several goals at the same time: (a) there is an increased saving in petroleum crude, since the alcohol is not merely a substitute for gasoline but rather a substitute for the octane-boosting additives used in the manufacture of unleaded gasoline; and (b) the production of fermentation ethanol for a fuel purpose can help revitalize the agricultural sector in different economics systems, thus becoming a road to economic development.

  7. Influence of fibre volume fraction and temperature on fatigue life of glass fibre reinforced plastics

    Directory of Open Access Journals (Sweden)

    Konrad Wegener

    2016-07-01

    Full Text Available The influence of fibre volume fraction and temperature on fatigue life of continuous glass fibre reinforced plastics is investigated in detail. The physical causes of the two effects on the slope of the S-N-curve in fibre direction at R = 0.1 are researched and can be explained with help of micrographs. A new phenomenological approach is presented to model both effects in fibre dominated laminates with different stacking sequences using only the static ultimate strength as an input. Static and fatigue tests of different layups and fibre volume fractions are performed at different temperatures to validate the fatigue life predictions. Additionally it is derived that there is an optimal fibre volume fraction regarding a minimum damage sum. This fibre volume fraction is dependent on a given loading spectra and can be calculated using the phenomenological model.

  8. Left ventricular volume determined from scintigraphy and digital angiography by a semi-automated geometric method

    Energy Technology Data Exchange (ETDEWEB)

    Seldin, D.W.; Esser, P.D.; Nichols, A.B.; Ratner, S.J.; Alderson, P.O.

    1983-12-01

    The utility of a semi-automatic method of measuring left ventricular (LV) volume geometrically from gated blood-pool studies and digital subtraction angiography (DSA) was investigated using computerized edge detection and spatial calibration algorithms. LAO LV volumes determined from gated blood-pool studies were compared to volumes obtained from contrast left ventriculograms in 21 patients and the applicability of this method to DSA was evaluated in 25 additional patients who also had conventional left ventriculography. There was excellent correlation between the two, both for radionuclide studies and for DSA. Computer-based geometric determinations of LV volume appear to be rapid, accurate, and less dependent on subjective operator decisions than previously reported geometric approaches.

  9. Thermal modelling of extrusion based additive manufacturing of composite materials

    DEFF Research Database (Denmark)

    Jensen, Mathias Laustsen; Sonne, Mads Rostgaard; Hattel, Jesper Henri

    2017-01-01

    One of the hottest topics regarding manufacturing these years is additive manufacturing (AM). AM is a young branch of manufacturing techniques, which by nature is disruptive due to its completely different manufacturing approach, wherein material is added instead of removed. By adding material...... process knowledge, and validating the generated toolpaths before the real manufacturing process takes place: Hence removing time consuming and expensive trial-and-error processes for new products. This study applies a 2D restricted finite volume model aimed to describe thermoplastic Acrylonitrille......-butadiene-styrene (ABS) and thermosetting polyurethane (PU) material extrusion processes. During the experimental evaluation of the produced models it is found that some critical material properties needs to be further investigated to increase the precision of the model. It is however also found that even with only...

  10. Biobased lubricant additives

    Science.gov (United States)

    Fully biobased lubricants are those formulated using all biobased ingredients, i.e. biobased base oils and biobased additives. Such formulations provide the maximum environmental, safety, and economic benefits expected from a biobased product. Currently, there are a number of biobased base oils that...

  11. Capital Cost: Pressurized Water Reactor Plant Volume 1

    Energy Technology Data Exchange (ETDEWEB)

    1977-06-01

    The investment cost study for the 1139-MW(e) pressurized water reactor (PWR) central station power plant consists of two volumes. This volume includes in addition to the foreword and summary, the plant description and the detailed cost estimate.

  12. INFLUENCE OF NATURAL ADDITIVES ON PROTEIN COMPLEX OF BREAD

    Directory of Open Access Journals (Sweden)

    Dana Urminská

    2010-11-01

    Full Text Available The study focuses on researching the influence of natural additives on certain technological characteristics of mixtures used for bread production, more particularly the influence of N substances in used raw material on selected qualitative parameters of bread. The blends for bread production to be analysed were prepared by mixing wheat flour with an addition of oat, buckwheat, lentil and chickpea wholegrain flour in different portions (10, 20, 30, 40 and 50 %. The experiment showed that the addition of natural additives worsened the protein complex of the blends used in bread production (worsening also qualitative parameters known as product volume. The loaves prepared with an addition of buckwheat, oat, lentil and chickpea were evaluated to be of a lesser quality from a technological viewpoint when compared with pure wheat loaves. The lower content of gluten forming proteins and the generally changed protein composition of blends due to additives caused a lower percentage of wet gluten content, its lower extensibility and swelling capacity. The sedimentation value (Zeleny index decreased proportionally with the increase of addition until the level was unsatisfactory for raw material intended for bakery purposes. The N content in experimental loaves was higher than in the reference loaves and it increased according to the selected additive and its portion in the blend (more with the addition of lentil and chickpea, less in case of buckwheat and oat which is considered as positive from a nutritional point of view. But from the technological point of view the additives did not show any positive influence and caused a lower loaf bread volume. The most significant decrease of the loaf bread volume was found with the addition of 50 % of buckwheat (- 45.6 %. Better results were obtained with a lower portion of the additive: loaf with an addition of 30 % of chickpea (volume decreased by 12.8 % > loaf with an addition of 30 % of lentil (volume

  13. Seeing and feeling volumes: The influence of shape on volume perception.

    Science.gov (United States)

    Kahrimanovic, Mirela; Bergmann Tiest, Wouter M; Kappers, Astrid M L

    2010-07-01

    The volume of common objects can be perceived visually, haptically or by a combination of both senses. The present study shows large effects of the object's shape on volume perception within all these modalities, with an average bias of 36%. In all conditions, the volume of a tetrahedron was overestimated compared to that of a cube or a sphere, and the volume of a cube was overestimated compared to that of a sphere. Additional analyses revealed that the biases could be explained by the dependence of the volume judgment on different geometric properties. During visual volume perception, the strategies depended on the objects that were compared and they were also subject-dependent. However, analysis of the haptic and bimodal data showed more consistent results and revealed that surface area of the stimuli influenced haptic as well as bimodal volume perception. This suggests that bimodal volume perception is more influenced by haptic input than by visual information.

  14. Conferences on Combinatorial and Additive Number Theory

    CERN Document Server

    2014-01-01

    This proceedings volume is based on papers presented at the Workshops on Combinatorial and Additive Number Theory (CANT), which were held at the Graduate Center of the City University of New York in 2011 and 2012. The goal of the workshops is to survey recent progress in combinatorial number theory and related parts of mathematics. The workshop attracts researchers and students who discuss the state-of-the-art, open problems, and future challenges in number theory.

  15. Longitudinal analysis of mouse SDOCT volumes

    Science.gov (United States)

    Antony, Bhavna J.; Carass, Aaron; Lang, Andrew; Kim, Byung-Jin; Zack, Donald J.; Prince, Jerry L.

    2017-03-01

    Spectral-domain optical coherence tomography (SDOCT), in addition to its routine clinical use in the diagnosis of ocular diseases, has begun to fund increasing use in animal studies. Animal models are frequently used to study disease mechanisms as well as to test drug efficacy. In particular, SDOCT provides the ability to study animals longitudinally and non-invasively over long periods of time. However, the lack of anatomical landmarks makes the longitudinal scan acquisition prone to inconsistencies in orientation. Here, we propose a method for the automated registration of mouse SDOCT volumes. The method begins by accurately segmenting the blood vessels and the optic nerve head region in the scans using a pixel classification approach. The segmented vessel maps from follow-up scans were registered using an iterative closest point (ICP) algorithm to the baseline scan to allow for the accurate longitudinal tracking of thickness changes. Eighteen SDOCT volumes from a light damage model study were used to train a random forest utilized in the pixel classification step. The area under the curve (AUC) in a leave-one-out study for the retinal blood vessels and the optic nerve head (ONH) was found to be 0.93 and 0.98, respectively. The complete proposed framework, the retinal vasculature segmentation and the ICP registration, was applied to a secondary set of scans obtained from a light damage model. A qualitative assessment of the registration showed no registration failures.

  16. Control volume based hydrocephalus research

    Science.gov (United States)

    Cohen, Benjamin; Voorhees, Abram; Wei, Timothy

    2008-11-01

    Hydrocephalus is a disease involving excess amounts of cerebral spinal fluid (CSF) in the brain. Recent research has shown correlations to pulsatility of blood flow through the brain. However, the problem to date has presented as too complex for much more than statistical analysis and understanding. This talk will highlight progress on developing a fundamental control volume approach to studying hydrocephalus. The specific goals are to select physiologically control volume(s), develop conservation equations along with the experimental capabilities to accurately quantify terms in those equations. To this end, an in vitro phantom is used as a simplified model of the human brain. The phantom's design consists of a rigid container filled with a compressible gel. The gel has a hollow spherical cavity representing a ventricle and a cylindrical passage representing the aquaducts. A computer controlled piston pump supplies pulsatile volume fluctuations into and out of the flow phantom. MRI is used to measure fluid velocity, and volume change as functions of time. Independent pressure measurements and flow rate measurements are used to calibrate the MRI data. These data are used as a framework for future work with live patients.

  17. DNA addition using linear self-assembly

    Institute of Scientific and Technical Information of China (English)

    ZHAO Jian; QIAN LuLu; LIU Qiang; ZHANG ZhiZhou; HE Lin

    2007-01-01

    This paper presents a DNA algorithm which adds two nonnegative binary integers using self-assembly in constant steps. The approach has the benefit of greater experimental simplicity when compared with previous DNA addition algorithms. For the addition of two binary n-bit integers, O(n) is different from DNA strands and only O(1) biochemical experimental procedures are required.

  18. Contexts for Column Addition and Subtraction

    Science.gov (United States)

    Lopez Fernandez, Jorge M.; Velazquez Estrella, Aileen

    2011-01-01

    In this article, the authors discuss their approach to column addition and subtraction algorithms. Adapting an original idea of Paul Cobb and Erna Yackel's from "A Contextual Investigation of Three-Digit Addition and Subtraction" related to packing and unpacking candy in a candy factory, the authors provided an analogous context by…

  19. Contexts for Column Addition and Subtraction

    Science.gov (United States)

    Lopez Fernandez, Jorge M.; Velazquez Estrella, Aileen

    2011-01-01

    In this article, the authors discuss their approach to column addition and subtraction algorithms. Adapting an original idea of Paul Cobb and Erna Yackel's from "A Contextual Investigation of Three-Digit Addition and Subtraction" related to packing and unpacking candy in a candy factory, the authors provided an analogous context by…

  20. Regional cerebellar volume and cognitive function from adolescence to late middle age.

    Science.gov (United States)

    Bernard, Jessica A; Leopold, Daniel R; Calhoun, Vince D; Mittal, Vijay A

    2015-03-01

    Cerebellar morphology and function have been implicated in a variety of developmental disorders, and in healthy aging. Although recent work has sought to characterize the relationships between volume and age in this structure during adolescence, young, and older adulthood, there have been no investigations of regional cerebellar volume from adolescence through late middle age. Middle age in particular has been largely understudied, and investigating this period of the lifespan may be especially important for our understanding of senescence. Understanding regional patterns of cerebellar volume with respect to age during this portion of the lifespan may provide important insight into healthy aging and cognitive function as well as pathology from adolescence into later life. We investigated regional cerebellar volume using a highly novel lobular segmentation approach in conjunction with a battery of cognitive tasks in a cross-sectional sample of 123 individuals from 12 to 65 years old. Our results indicated that regional cerebellar volumes show different patterns with respect to age. In particular, the more posterior aspect of the neocerebellum follows a quadratic "inverse-U" pattern while the vermis and anterior cerebellum follow logarithmic patterns. In addition, we quantified the relationships between age and a variety of cognitive assessments and found relationships between regional cerebellar volumes and performance. Finally, exploratory analyses of sex differences in the relationships between regional cerebellar volume, age, and cognition were investigated. Taken together, these results provide key insights into the development and aging of the human cerebellum, and its role in cognitive function across the lifespan.

  1. Ovarian volume throughout life

    DEFF Research Database (Denmark)

    Kelsey, Thomas W; Dodwell, Sarah K; Wilkinson, A Graham

    2013-01-01

    cancer. To date there is no normative model of ovarian volume throughout life. By searching the published literature for ovarian volume in healthy females, and using our own data from multiple sources (combined n=59,994) we have generated and robustly validated the first model of ovarian volume from...... to about 2.8 mL (95% CI 2.7-2.9 mL) at the menopause and smaller volumes thereafter. Our model allows us to generate normal values and ranges for ovarian volume throughout life. This is the first validated normative model of ovarian volume from conception to old age; it will be of use in the diagnosis...

  2. Tweaking Synchronisation by Link Addition

    CERN Document Server

    Schultz, Paul; Eroglu, Deniz; Stemler, Thomas; Ávila, G Marcelo Ramírez; Rodrigues, Francisco A; Kurths, Jürgen

    2016-01-01

    Natural and man-made networks often possess locally tree-like sub-structures. Taking such tree networks as our starting point, we show how the addition of links changes the synchronization properties of the network. We focus on two different methods of link addition. The first method adds single links that create cycles of a well-defined length. Following a topological approach we introduce cycles of varying length and analyze how this feature, as well as the position in the network, alters the synchronous behaviour. We show that in particular short cycles can lead to a maximum change of the Laplacian's eigenvalue spectrum, dictating the synchronization properties of such networks. The second method connects a certain proportion of the initially unconnected nodes. We simulate dynamical systems on these network topologies, with the nodes' local dynamics being either a discrete or continuous. Here our main result is that a certain amount of additional links, with the relative position in the network being cruci...

  3. Additive Manufacturing Applications for Wind Turbines

    OpenAIRE

    Wahlström, Niklas; Gabrielsson, Oscar

    2017-01-01

    Additive manufacturing (AM), also known as 3D-printing is an automated manufacturing process in which the component is built layer upon layer from a predefined 3D computer model. In contrast to conventional manufacturing processes where a vast volume of material is wasted due to machining, AM only uses the material that the component consists of. In addition to material savings, the method has a number of potential benefits. Two of these are (1) a large design freedom which enables the produc...

  4. Sarks as additional fermions

    Science.gov (United States)

    Agrawal, Jyoti; Frampton, Paul H.; Jack Ng, Y.; Nishino, Hitoshi; Yasuda, Osamu

    1991-03-01

    An extension of the standard model is proposed. The gauge group is SU(2) X ⊗ SU(3) C ⊗ SU(2) S ⊗ U(1) Q, where all gauge symmetries are unbroken. The colour and electric charge are combined with SU(2) S which becomes strongly coupled at approximately 500 GeV and binds preons to form fermionic and vector bound states. The usual quarks and leptons are singlets under SU(2) X but additional fermions, called sarks. transform under it and the electroweak group. The present model explains why no more than three light quark-lepton families can exist. Neutral sark baryons, called narks, are candidates for the cosmological dark matter having the characteristics designed for WIMPS. Further phenomenological implications of sarks are analyzed i including electron-positron annihilation. Z 0 decay, flavor-changing neutral currents. baryon-number non-conservation, sarkonium and the neutron electric dipole moment.

  5. Volume Ray Casting with Peak Finding and Differential Sampling

    KAUST Repository

    Knoll, A.

    2009-11-01

    Direct volume rendering and isosurfacing are ubiquitous rendering techniques in scientific visualization, commonly employed in imaging 3D data from simulation and scan sources. Conventionally, these methods have been treated as separate modalities, necessitating different sampling strategies and rendering algorithms. In reality, an isosurface is a special case of a transfer function, namely a Dirac impulse at a given isovalue. However, artifact-free rendering of discrete isosurfaces in a volume rendering framework is an elusive goal, requiring either infinite sampling or smoothing of the transfer function. While preintegration approaches solve the most obvious deficiencies in handling sharp transfer functions, artifacts can still result, limiting classification. In this paper, we introduce a method for rendering such features by explicitly solving for isovalues within the volume rendering integral. In addition, we present a sampling strategy inspired by ray differentials that automatically matches the frequency of the image plane, resulting in fewer artifacts near the eye and better overall performance. These techniques exhibit clear advantages over standard uniform ray casting with and without preintegration, and allow for high-quality interactive volume rendering with sharp C0 transfer functions. © 2009 IEEE.

  6. Effectiveness of quantitative MAA SPECT/CT for the definition of vascularized hepatic volume and dosimetric approach: phantom validation and clinical preliminary results in patients with complex hepatic vascularization treated with yttrium-90-labeled microspheres.

    Science.gov (United States)

    Garin, Etienne; Lenoir, Laurence; Rolland, Yan; Laffont, Sophie; Pracht, Marc; Mesbah, Habiba; Porée, Philippe; Ardisson, Valérie; Bourguet, Patrick; Clement, Bruno; Boucher, Eveline

    2011-12-01

    The goal of this study was to assess the use of quantitative single-photon emission computed tomography/computed tomography (SPECT/CT) analysis for vascularized volume measurements in the use of the yttrium-90-radiolabeled microspheres (TheraSphere). A phantom study was conducted for the validation of SPECT/CT volume measurement. SPECT/CT quantitative analysis was used for the measurement of the volume of distribution of the albumin macroaggregates (MAA; i.e., the vascularized volume) in the liver and the tumor, and the total activity contained in the liver and the tumor in four consecutive patients presenting with a complex liver vascularization referred for a treatment with TheraSphere. SPECT/CT volume measurement proved to be accurate (mean error data, instead of angiography and CT data, results in modifying the activity injected for three treatments of eight. Moreover, quantitative analysis of SPECT/CT allows us to calculate the absorbed dose in the tumor and in the healthy liver, leading to doubling of the injected activity for one treatment of eight. MAA SPECT/CT is accurate for volume measurements. It provides a valuable contribution to the therapeutic planning of patients presenting with complex hepatic vascularization, in particular for calculating the vascularized liver volume, the activity to be injected and the absorbed doses. Studies should be conducted to assess the role of quantitative MAA/SPECT CT in therapeutic planning.

  7. The effectiveness of selected feed and water additives for reducing Salmonella spp. of public health importance in broiler chickens: a systematic review, meta-analysis, and meta-regression approach.

    Science.gov (United States)

    Totton, Sarah C; Farrar, Ashley M; Wilkins, Wendy; Bucher, Oliver; Waddell, Lisa A; Wilhelm, Barbara J; McEwen, Scott A; Rajić, Andrijana

    2012-10-01

    Eating inappropriately prepared poultry meat is a major cause of foodborne salmonellosis. Our objectives were to determine the efficacy of feed and water additives (other than competitive exclusion and antimicrobials) on reducing Salmonella prevalence or concentration in broiler chickens using systematic review-meta-analysis and to explore sources of heterogeneity found in the meta-analysis through meta-regression. Six electronic databases were searched (Current Contents (1999-2009), Agricola (1924-2009), MEDLINE (1860-2009), Scopus (1960-2009), Centre for Agricultural Bioscience (CAB) (1913-2009), and CAB Global Health (1971-2009)), five topic experts were contacted, and the bibliographies of review articles and a topic-relevant textbook were manually searched to identify all relevant research. Study inclusion criteria comprised: English-language primary research investigating the effects of feed and water additives on the Salmonella prevalence or concentration in broiler chickens. Data extraction and study methodological assessment were conducted by two reviewers independently using pretested forms. Seventy challenge studies (n=910 unique treatment-control comparisons), seven controlled studies (n=154), and one quasi-experiment (n=1) met the inclusion criteria. Compared to an assumed control group prevalence of 44 of 1000 broilers, random-effects meta-analysis indicated that the Salmonella cecal colonization in groups with prebiotics (fructooligosaccharide, lactose, whey, dried milk, lactulose, lactosucrose, sucrose, maltose, mannanoligosaccharide) added to feed or water was 15 out of 1000 broilers; with lactose added to feed or water it was 10 out of 1000 broilers; with experimental chlorate product (ECP) added to feed or water it was 21 out of 1000. For ECP the concentration of Salmonella in the ceca was decreased by 0.61 log(10)cfu/g in the treated group compared to the control group. Significant heterogeneity (Cochran's Q-statistic p≤0.10) was observed

  8. Computational approach to Riemann surfaces

    CERN Document Server

    Klein, Christian

    2011-01-01

    This volume offers a well-structured overview of existent computational approaches to Riemann surfaces and those currently in development. The authors of the contributions represent the groups providing publically available numerical codes in this field. Thus this volume illustrates which software tools are available and how they can be used in practice. In addition examples for solutions to partial differential equations and in surface theory are presented. The intended audience of this book is twofold. It can be used as a textbook for a graduate course in numerics of Riemann surfaces, in which case the standard undergraduate background, i.e., calculus and linear algebra, is required. In particular, no knowledge of the theory of Riemann surfaces is expected; the necessary background in this theory is contained in the Introduction chapter. At the same time, this book is also intended for specialists in geometry and mathematical physics applying the theory of Riemann surfaces in their research. It is the first...

  9. Additive-driven assembly of block copolymers

    Science.gov (United States)

    Lin, Ying; Daga, Vikram; Anderson, Eric; Watkins, James

    2011-03-01

    One challenge to the formation of well ordered hybrid materials is the incorporation of nanoscale additives including metal, semiconductor and dielectric nanoparticles at high loadings while maintaining strong segregation. Here we describe the molecular and functional design of small molecule and nanoparticle additives that enhance phase segregation in their block copolymer host and enable high additive loadings. Our approach includes the use of hydrogen bond interactions between the functional groups on the additive or particle that serve as hydrogen bond donors and one segment of the block copolymer containing hydrogen bond acceptors. Further, the additives show strong selectively towards the targeted domains, leading to enhancements in contrast between properties of the phases. In addition to structural changes, we explore how large changes in the thermal and mechanical properties occur upon incorporation of the additives. Generalization of this additive-induced ordering strategy to various block copolymers will be discussed.

  10. Mean nuclear volume

    DEFF Research Database (Denmark)

    Mogensen, O.; Sørensen, Flemming Brandt; Bichel, P.

    1999-01-01

    We evaluated the following nine parameters with respect to their prognostic value in females with endometrial cancer: four stereologic parameters [mean nuclear volume (MNV), nuclear volume fraction, nuclear index and mitotic index], the immunohistochemical expression of cancer antigen (CA125...

  11. Business models for additive manufacturing

    DEFF Research Database (Denmark)

    Hadar, Ronen; Bilberg, Arne; Bogers, Marcel

    2015-01-01

    Digital fabrication — including additive manufacturing (AM), rapid prototyping and 3D printing — has the potential to revolutionize the way in which products are produced and delivered to the customer. Therefore, it challenges companies to reinvent their business model — describing the logic...... of creating and capturing value. In this paper, we explore the implications that AM technologies have for manufacturing systems in the new business models that they enable. In particular, we consider how a consumer goods manufacturer can organize the operations of a more open business model when moving from...... a manufacturer-centric to a consumer-centric value logic. A major shift includes a move from centralized to decentralized supply chains, where consumer goods manufacturers can implement a “hybrid” approach with a focus on localization and accessibility or develop a fully personalized model where the consumer...

  12. Control volume based hydrocephalus research; analysis of human data

    Science.gov (United States)

    Cohen, Benjamin; Wei, Timothy; Voorhees, Abram; Madsen, Joseph; Anor, Tomer

    2010-11-01

    Hydrocephalus is a neuropathophysiological disorder primarily diagnosed by increased cerebrospinal fluid volume and pressure within the brain. To date, utilization of clinical measurements have been limited to understanding of the relative amplitude and timing of flow, volume and pressure waveforms; qualitative approaches without a clear framework for meaningful quantitative comparison. Pressure volume models and electric circuit analogs enforce volume conservation principles in terms of pressure. Control volume analysis, through the integral mass and momentum conservation equations, ensures that pressure and volume are accounted for using first principles fluid physics. This approach is able to directly incorporate the diverse measurements obtained by clinicians into a simple, direct and robust mechanics based framework. Clinical data obtained for analysis are discussed along with data processing techniques used to extract terms in the conservation equation. Control volume analysis provides a non-invasive, physics-based approach to extracting pressure information from magnetic resonance velocity data that cannot be measured directly by pressure instrumentation.

  13. A simple approach to obtain hybrid Au-loaded polymeric nanoparticles with a tunable metal load† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c5nr06850a Click here for additional data file.

    Science.gov (United States)

    Luque-Michel, Edurne; Larrea, Ane; Lahuerta, Celia; Imbuluzqueta, Edurne; Arruebo, Manuel; Santamaría, Jesús

    2016-01-01

    A new strategy to nanoengineer multi-functional polymer–metal hybrid nanostructures is reported. By using this protocol the hurdles of most of the current developments concerning covalent and non-covalent attachment of polymers to preformed inorganic nanoparticles (NPs) are overcome. The strategy is based on the in situ reduction of metal precursors using the polymeric nanoparticle as a nanoreactor. Gold nanoparticles and poly(dl-lactic-co-glycolic acid), PLGA, are located in the core and shell, respectively. This novel technique enables the production of PLGA NPs smaller than 200 nm that bear either a single encapsulated Au NP or several smaller NPs with tunable sizes and a 100% loading efficiency. In situ reduction of Au ions inside the polymeric NPs was achieved on demand by using heat to activate the reductive effect of citrate ions. In addition, we show that the loading of the resulting Au NPs inside the PLGA NPs is highly dependent on the surfactant used. Electron microscopy, laser irradiation, UV-Vis and fluorescence spectroscopy characterization techniques confirm the location of Au nanoparticles. These promising results indicate that these hybrid nanomaterials could be used in theranostic applications or as contrast agents in dark-field imaging and computed tomography. PMID:26612770

  14. A new and economic approach to synthesize and fabricate bioactive diopside ceramics using a modified domestic microwave oven. Part 2: effect of P2O5 additions on diopside bioactivity and mechanical properties.

    Science.gov (United States)

    Zouai, Souheila; Harabi, Abdelhamid; Karboua, Noureddine; Harabi, Esma; Chehlatt, Sihem; Barama, Salah-Edine; Zaiou, Soumia; Bouzerara, Ferhat; Guerfa, Fatiha

    2016-04-01

    In this work, diopside based ceramics was obtained by solid state reaction using conventional sintering (CS) and microwave sintering (MS). Moreover, different amounts of P2O5 (0.5-5.0 wt.%) have been added. It has been found that a relative density up to 95% theoretical was obtained for diopside containing 2.0 and 5.0 wt.% P2O5, sintered at 1250 °C for 2h and at 1075 °C only for 15 min using CS and MS. Excellent values of micro hardness (7.4 ± 0.1 GPa) and 3 point flexural strength (about 270 MPa) for samples containing 5 wt.% P2O5, sintered at 1075 °C for 15 min using MS were measured. Besides this, a relatively low weight loss ratio has been measured (0.01%) for diopside samples containing 5 wt.% P2O5, sintered under the same conditions, after soaking in physiological salt solution for 2 days. Additionally, the bioactivity of diopside by the possibility of formation of apatite on the surface of pure diopside and diopside containing 2 wt.% of P2O5 immersed in simulated body fluid (SBF) was also confirmed. Finally, particular nano-sized of Carbonated hydroxyapatite (CHA) crystals (rice shaped) were formed and covered the surface of these samples, soaked in SBF solution for 14 days.

  15. MODIFICATION OF THE ANALYTIC HIERARCHY PROCESS (AHP METHOD USING FUZZY LOGIC: FUZZY AHP APPROACH AS A SUPPORT TO THE DECISION MAKING PROCESS CONCERNING ENGAGEMENT OF THE GROUP FOR ADDITIONAL HINDERING

    Directory of Open Access Journals (Sweden)

    Darko Božanić

    2015-11-01

    Full Text Available This paper presents the modification of the AHP method, which takes into account the degree of suspense of decision maker, that is it allows that decision maker, with a certain degree of conviction (which is usually less than 100%, defines which linguistic expression corresponds to optimality criteria comparison. To determine the criteria weights and alternative values, fuzzy numbers are used since they are very suitable for the expression of vagueness and uncertainty. In this way, after applying the AHP method, we obtained values of criterion functions for each of the examined alternatives, which corresponds to the value determined by the degree of conviction. This provides that for different values of the degree of conviction can be made generation of different sets of criterion functions values. The set model was tested on choosing directions of action of the Group for additional hindering, as a procedure wich is often accompanied by greater or lesser degree of uncertainty of criteria that are necessary in relevant decision making

  16. Flow characteristics of metallic powder grains for additive manufacturing

    Science.gov (United States)

    Peters, Bernhard; Pozzetti, Gabriele

    2017-06-01

    Directed energy deposition technologies for additive manufacturing such as laser selective melting (SLM) or electron beam melting (EBM) is a fast growing technique mainly due to its flexibility in product design. However, the process is a complex interaction of multi-physics on multiple length scales that are still not entirely understood. A particular challenging task are the flow characteristics of metallic powder ejected as jets from a nozzle and shielded by an inert turbulent gas flow. Therefore, the objective is to describe numerically the complex interaction between turbulent flow and powder grains. In order to include both several physical processes and length scales an Euler-Lagrange technology is applied. Within this framework powder is treated by the Discrete-Element-Method, while gas flow is described by Euler approaches as found in classical Computational Fluid Dynamics (CFD). The described method succeeded in delivering more accuracy and consistency than a standard approach based on the volume averaging technique and therefore, is suited for the solution of problems within an engineering framework.

  17. Flow characteristics of metallic powder grains for additive manufacturing

    Directory of Open Access Journals (Sweden)

    Peters Bernhard

    2017-01-01

    Full Text Available Directed energy deposition technologies for additive manufacturing such as laser selective melting (SLM or electron beam melting (EBM is a fast growing technique mainly due to its flexibility in product design. However, the process is a complex interaction of multi-physics on multiple length scales that are still not entirely understood. A particular challenging task are the flow characteristics of metallic powder ejected as jets from a nozzle and shielded by an inert turbulent gas flow. Therefore, the objective is to describe numerically the complex interaction between turbulent flow and powder grains. In order to include both several physical processes and length scales an Euler-Lagrange technology is applied. Within this framework powder is treated by the Discrete-Element-Method, while gas flow is described by Euler approaches as found in classical Computational Fluid Dynamics (CFD. The described method succeeded in delivering more accuracy and consistency than a standard approach based on the volume averaging technique and therefore, is suited for the solution of problems within an engineering framework.

  18. Optimizing Crystal Volume for Neutron Diffraction Studies

    Science.gov (United States)

    Snell, E. H.

    2003-01-01

    For structural studies with neutron diffraction more intense neutron sources, improved sensitivity detector and larger volume crystals are all means by which the science is being advanced to enable studies on a wider range of samples. We have chosen a simplistic approach using a well understood crystallization method, with minimal amounts of sample and using design of experiment techniques to maximize the crystal volume all for minimum effort. Examples of the application are given.

  19. Finite volume hydromechanical simulation in porous media.

    Science.gov (United States)

    Nordbotten, Jan Martin

    2014-05-01

    Cell-centered finite volume methods are prevailing in numerical simulation of flow in porous media. However, due to the lack of cell-centered finite volume methods for mechanics, coupled flow and deformation is usually treated either by coupled finite-volume-finite element discretizations, or within a finite element setting. The former approach is unfavorable as it introduces two separate grid structures, while the latter approach loses the advantages of finite volume methods for the flow equation. Recently, we proposed a cell-centered finite volume method for elasticity. Herein, we explore the applicability of this novel method to provide a compatible finite volume discretization for coupled hydromechanic flows in porous media. We detail in particular the issue of coupling terms, and show how this is naturally handled. Furthermore, we observe how the cell-centered finite volume framework naturally allows for modeling fractured and fracturing porous media through internal boundary conditions. We support the discussion with a set of numerical examples: the convergence properties of the coupled scheme are first investigated; second, we illustrate the practical applicability of the method both for fractured and heterogeneous media.

  20. Non-additive measure and integral

    CERN Document Server

    Denneberg, Dieter

    1994-01-01

    Non-Additive Measure and Integral is the first systematic approach to the subject. Much of the additive theory (convergence theorems, Lebesgue spaces, representation theorems) is generalized, at least for submodular measures which are characterized by having a subadditive integral. The theory is of interest for applications to economic decision theory (decisions under risk and uncertainty), to statistics (including belief functions, fuzzy measures) to cooperative game theory, artificial intelligence, insurance, etc. Non-Additive Measure and Integral collects the results of scattered and often isolated approaches to non-additive measures and their integrals which originate in pure mathematics, potential theory, statistics, game theory, economic decision theory and other fields of application. It unifies, simplifies and generalizes known results and supplements the theory with new results, thus providing a sound basis for applications and further research in this growing field of increasing interest. It also co...

  1. Trading Volume and Stock Indices: A Test of Technical Analysis

    Directory of Open Access Journals (Sweden)

    Paul Abbondante

    2010-01-01

    Full Text Available Problem statement: Technical analysis and its emphasis on trading volume has been used to analyze movements in individual stock prices and make investment recommendations to either buy or sell that stock. Little attention has been paid to investigating the relationship between trading volume and various stock indices. Approach: Since stock indices track overall stock market movements, trends in trading volume could be used to forecast future stock market trends. Instead of focusing only on individual stocks, this study will examine movements in major stock markets as a whole. Regression analysis was used to investigate the relationship between trading volume and five popular stock indices using daily data from January, 2000 to June, 2010. A lag of 5 days was used because this represents the prior week of trading volume. The total sample size ranges from 1,534-2,638 to observations. Smaller samples were used to test the investment horizon that explains movements of the indices more completely. Results: The F statistics were significant for samples using 6 and 16 months of data. The F statistic was not significant using a sample of 1 month of data. This is surprising given the short term focus of technical analysis. The results indicate that above-average returns can be achieved using futures, options and exchange traded funds which track these indices. Conclusion: Future research efforts will include out-of-sample forecasting to determine if above-average returns can be achieved. Additional research can be conducted to determine the optimal number of lags for each index.

  2. Volume Regulated Channels

    DEFF Research Database (Denmark)

    Klausen, Thomas Kjær

    - serves a multitude of functions in the mammalian cell, regulating the membrane potential (Em), cell volume, protein activity and the driving force for facilitated transporters giving Cl- and Cl- channels a major potential of regulating cellular function. These functions include control of the cell cycle...... of volume perturbations evolution have developed system of channels and transporters to tightly control volume homeostasis. In the past decades evidence has been mounting, that the importance of these volume regulated channels and transporters are not restricted to the defense of cellular volume......, controlled cell death and cellular migration. Volume regulatory mechanisms has long been in focus for regulating cellular proliferation and my thesis work have been focusing on the role of Cl- channels in proliferation with specific emphasis on ICl, swell. Pharmacological blockage of the ubiquitously...

  3. Volume and surface contributions to the nuclear symmetry energy within the coherent density fluctuation model

    CERN Document Server

    Antonov, A N; Sarriguren, P; de Guerra, E Moya

    2016-01-01

    The volume and surface components of the nuclear symmetry energy (NSE) and their ratio are calculated within the coherent density fluctuation model (CDFM). The estimations use the results of the model for the NSE in finite nuclei based on the Brueckner energy-density functional for nuclear matter. In addition, we present results for the NSE and its volume and surface contributions obtained by using the Skyrme energy-density functional. The CDFM weight function is obtained using the proton and neutron densities from the self-consistent HF+BCS method with Skyrme interactions. We present and discuss the values of the volume and surface contributions to the NSE and their ratio obtained for the Ni, Sn, and Pb isotopic chains studying their isotopic sensitivity. The results are compared with estimations of other approaches which have used available experimental data on binding energies, neutron-skin thicknesses, excitation energies to isobaric analog states (IAS) and also with results of other theoretical methods.

  4. Controllable Microdroplet Splitting via Additional Lateral Flow and its Application in Rapid Synthesis of Multi-scale Microspheres

    KAUST Repository

    Zhou, Bingpu

    2015-01-01

    In this paper, we demonstrate that controllable microdroplet splitting could be obtained via additional lateral flow with simplicity and high controllability. The volume ratio of the two splitting products can be flexibly regulated by adjusting the flow rate ratio between the main and additional lateral flows. The splitting phenomena under different main flow rates were investigated. A volume ratio up to 200 : 1 of the two daughter droplets under a relatively higher main flow rate was experimentally achieved based on our approach. In this case, we have successfully achieved uniform daughter droplets with a smallest diameter of ∼19.5 ± 1.6 μm. With such a design, we have synthesized uniform PEGDA hydrogel microspheres with diameters ranging from ∼30 μm to over hundred of micrometers simultaneously.

  5. Mechanism and kinetics of addition polymerizations

    CERN Document Server

    Kucera, M

    1991-01-01

    This volume presents an up-to-date survey of knowledge concerning addition type polymerizations. It contains nine chapters, each of which covers a particular basic term. Whenever necessary, the phenomena are discussed from the viewpoint of both stationary and non-stationary state of radical, ionic (i.e. anionic and cationic) and coordination polymerization. Special attention has been paid to the propagation process. It provides not only a general overview but also information on important special cases (theoretical conditions of propagation, influence of external factors, controlled propagatio

  6. CSCE annual conference. Volume 5: sustainable development, environment, geotechnical engineering, transportation

    Energy Technology Data Exchange (ETDEWEB)

    Leduc, R.; Johnson, C.; Gordon, M.; Lupien, C. [eds.

    1997-12-31

    Forty papers on sustainable development, environment, geotechnical engineering, and transportation are contained in this volume. Seven additional volumes contain 246 papers presented at the plenary sessions and sessions on history and education and the Confederation Bridge (volume 1); 2nd CSCE Construction Specialty Conference (volume 2); 13th Canadian Hydrotechnical Conference (volume 3); 2nd Symposium on Applied Mechanics, structures, and seismic engineering (volume 4); structures: composite materials, structural systems, and telecommunication towers (volume 6); structures: conception, concrete and reinforced concrete structures, and bridges (volume 7); and agricultural engineering, soil and water engineering, energy and processing/food engineering, machinery systems, waste management, and information and computer technologies (volume A).

  7. Altitude acclimatization and blood volume: effects of exogenous erythrocyte volume expansion

    DEFF Research Database (Denmark)

    Sawka, M N; Young, Jette Feveile; Rock, P B;

    1996-01-01

    We studied sea-level residents during 13 days of altitude acclimatization to determine 1) altitude acclimatization effects on erythrocyte volume and plasma volume, 2) if exogenous erythrocyte volume expansion alters subsequent erythrocyte volume and plasma volume adaptations, 3) if an increased...... blood oxygen content alters erythropoietin responses during altitude acclimatization, and 4) mechanisms responsible for plasma loss at altitude. Sixteen healthy men had a series of hematologic measurements made at sea level, on the first and ninth days of altitude (4,300 m) residence, and after...... had no effect; in addition, initially at altitude, blood oxygen content was 8% higher in erythrocyte-infused than in saline-infused subjects. The new findings regarding altitude acclimatization are summarized as follows: 1) erythrocyte volume does not change during the first 13 days...

  8. Precision volume measurement system.

    Energy Technology Data Exchange (ETDEWEB)

    Fischer, Erin E.; Shugard, Andrew D.

    2004-11-01

    A new precision volume measurement system based on a Kansas City Plant (KCP) design was built to support the volume measurement needs of the Gas Transfer Systems (GTS) department at Sandia National Labs (SNL) in California. An engineering study was undertaken to verify or refute KCP's claims of 0.5% accuracy. The study assesses the accuracy and precision of the system. The system uses the ideal gas law and precise pressure measurements (of low-pressure helium) in a temperature and computer controlled environment to ratio a known volume to an unknown volume.

  9. Enhanced performance large volume dissolution-DNP

    DEFF Research Database (Denmark)

    Bowen, Sean; Ardenkjær-Larsen, Jan Henrik

    2014-01-01

    A systematic study of the performance of the dissolution process in dissolution-DNP is presented. A relatively simple set of modifications is made to the standard Hypersense dissolution system to enable polarization of large volume samples. These consist of a large volume sample cup along...... with supporting modifications to the dissolution head and related components. Additional modifications were made to support the mapping of the temperature/pressure space of the dissolution process as well as enabling the use of large volumes of solvent and improving the robustness of the system. No loss...

  10. Neutron Characterization for Additive Manufacturing

    Science.gov (United States)

    Watkins, Thomas; Bilheux, Hassina; An, Ke; Payzant, Andrew; DeHoff, Ryan; Duty, Chad; Peter, William; Blue, Craig; Brice, Craig A.

    2013-01-01

    Oak Ridge National Laboratory (ORNL) is leveraging decades of experience in neutron characterization of advanced materials together with resources such as the Spallation Neutron Source (SNS) and the High Flux Isotope Reactor (HFIR) shown in Fig. 1 to solve challenging problems in additive manufacturing (AM). Additive manufacturing, or three-dimensional (3-D) printing, is a rapidly maturing technology wherein components are built by selectively adding feedstock material at locations specified by a computer model. The majority of these technologies use thermally driven phase change mechanisms to convert the feedstock into functioning material. As the molten material cools and solidifies, the component is subjected to significant thermal gradients, generating significant internal stresses throughout the part (Fig. 2). As layers are added, inherent residual stresses cause warping and distortions that lead to geometrical differences between the final part and the original computer generated design. This effect also limits geometries that can be fabricated using AM, such as thin-walled, high-aspect- ratio, and overhanging structures. Distortion may be minimized by intelligent toolpath planning or strategic placement of support structures, but these approaches are not well understood and often "Edisonian" in nature. Residual stresses can also impact component performance during operation. For example, in a thermally cycled environment such as a high-pressure turbine engine, residual stresses can cause components to distort unpredictably. Different thermal treatments on as-fabricated AM components have been used to minimize residual stress, but components still retain a nonhomogeneous stress state and/or demonstrate a relaxation-derived geometric distortion. Industry, federal laboratory, and university collaboration is needed to address these challenges and enable the U.S. to compete in the global market. Work is currently being conducted on AM technologies at the ORNL

  11. Fast global interactive volume segmentation with regional supervoxel descriptors

    Science.gov (United States)

    Luengo, Imanol; Basham, Mark; French, Andrew P.

    2016-03-01

    In this paper we propose a novel approach towards fast multi-class volume segmentation that exploits supervoxels in order to reduce complexity, time and memory requirements. Current methods for biomedical image segmentation typically require either complex mathematical models with slow convergence, or expensive-to-calculate image features, which makes them non-feasible for large volumes with many objects (tens to hundreds) of different classes, as is typical in modern medical and biological datasets. Recently, graphical models such as Markov Random Fields (MRF) or Conditional Random Fields (CRF) are having a huge impact in different computer vision areas (e.g. image parsing, object detection, object recognition) as they provide global regularization for multiclass problems over an energy minimization framework. These models have yet to find impact in biomedical imaging due to complexities in training and slow inference in 3D images due to the very large number of voxels. Here, we define an interactive segmentation approach over a supervoxel space by first defining novel, robust and fast regional descriptors for supervoxels. Then, a hierarchical segmentation approach is adopted by training Contextual Extremely Random Forests in a user-defined label hierarchy where the classification output of the previous layer is used as additional features to train a new classifier to refine more detailed label information. This hierarchical model yields final class likelihoods for supervoxels which are finally refined by a MRF model for 3D segmentation. Results demonstrate the effectiveness on a challenging cryo-soft X-ray tomography dataset by segmenting cell areas with only a few user scribbles as the input for our algorithm. Further results demonstrate the effectiveness of our method to fully extract different organelles from the cell volume with another few seconds of user interaction.

  12. Fully additive chip packaging: science or fiction?

    NARCIS (Netherlands)

    Oosterhuis, G.; Zon, C.M.B. van der; Maalderink, H.H.

    2011-01-01

    The current trend in IC packaging towards an ever increasing degree of integration, combined with a high level of production flexibility calls for novel approaches in manufacturing. To address these challenges in a flexible manufacturing setting, TNO investigated to what extend mask-less additive ma

  13. Fully additive chip packaging: science or fiction?

    NARCIS (Netherlands)

    Oosterhuis, G.; Zon, C.M.B. van der; Maalderink, H.H.

    2011-01-01

    The current trend in IC packaging towards an ever increasing degree of integration, combined with a high level of production flexibility calls for novel approaches in manufacturing. To address these challenges in a flexible manufacturing setting, TNO investigated to what extend mask-less additive ma

  14. Fully additive chip packaging: science or fiction?

    NARCIS (Netherlands)

    Oosterhuis, G.; Zon, C.M.B. van der; Maalderink, H.H.

    2011-01-01

    The current trend in IC packaging towards an ever increasing degree of integration, combined with a high level of production flexibility calls for novel approaches in manufacturing. To address these challenges in a flexible manufacturing setting, TNO investigated to what extend mask-less additive

  15. Variable volume combustor

    Energy Technology Data Exchange (ETDEWEB)

    Ostebee, Heath Michael; Ziminsky, Willy Steve; Johnson, Thomas Edward; Keener, Christopher Paul

    2017-01-17

    The present application provides a variable volume combustor for use with a gas turbine engine. The variable volume combustor may include a liner, a number of micro-mixer fuel nozzles positioned within the liner, and a linear actuator so as to maneuver the micro-mixer fuel nozzles axially along the liner.

  16. A Finitely Additive White Noise Approach to Nonlinear Filtering.

    Science.gov (United States)

    1982-10-01

    processes, J. of Multivariate Analysis, 1 (1971). [181. J.L. Lions, Equation differentielles operationnelles et problemes aux limites, Springer-Verlag (1961...Verlag, (1979). [24]. J. Szpirglas, Sur l’equivalence d’equations differentielles stochastiques a valeurs mesures intervenant dans le filtrage Markovien...filtering.I Thi s re ea rch h s e u p p o rted by AF OSR Gran t No . 49620 82 r 0009 . 0. Introduction The theory of Ito stochastic differential equations

  17. Additive Biomanufacturing : An Advanced Approach for Periodontal Tissue Regeneration

    NARCIS (Netherlands)

    Carter, Sarah-Sophia D; Vaquette, Cedryck; Ivanovski, Saso; Hutmacher, Dietmar W; Malda, Jos

    2016-01-01

    Periodontitis is defined as a chronic inflammatory condition, characterized by destruction of the periodontium, composed of hard (i.e. alveolar bone and cementum) and soft tissues (i.e. gingiva and periodontal ligament) surrounding and supporting the teeth. In severe cases, reduced periodontal suppo

  18. Volume Regulated Channels

    DEFF Research Database (Denmark)

    Klausen, Thomas Kjær

    of volume perturbations evolution have developed system of channels and transporters to tightly control volume homeostasis. In the past decades evidence has been mounting, that the importance of these volume regulated channels and transporters are not restricted to the defense of cellular volume...... but are also essential for a number of physiological processes such as proliferation, controlled cell death, migration and endocrinology. The thesis have been focusing on two Channels, namely the swelling activated Cl- channel (ICl, swell) and the transient receptor potential Vanilloid (TRPV4) channel. I: Cl......- serves a multitude of functions in the mammalian cell, regulating the membrane potential (Em), cell volume, protein activity and the driving force for facilitated transporters giving Cl- and Cl- channels a major potential of regulating cellular function. These functions include control of the cell cycle...

  19. Cellwise conservative unsplit advection for the volume of fluid method

    DEFF Research Database (Denmark)

    Comminal, Raphaël; Spangenberg, Jon; Hattel, Jesper Henri

    2015-01-01

    We present a cellwise conservative unsplit (CCU) advection scheme for the volume of fluid method (VOF) in 2D. Contrary to other schemes based on explicit calculations of the flux balances, the CCU advection adopts a cellwise approach where the pre-images of the control volumes are traced backward......We present a cellwise conservative unsplit (CCU) advection scheme for the volume of fluid method (VOF) in 2D. Contrary to other schemes based on explicit calculations of the flux balances, the CCU advection adopts a cellwise approach where the pre-images of the control volumes are traced...

  20. Programmatic methods for addressing contaminated volume uncertainties.

    Energy Technology Data Exchange (ETDEWEB)

    DURHAM, L.A.; JOHNSON, R.L.; RIEMAN, C.R.; SPECTOR, H.L.; Environmental Science Division; U.S. ARMY CORPS OF ENGINEERS BUFFALO DISTRICT

    2007-01-01

    Accurate estimates of the volumes of contaminated soils or sediments are critical to effective program planning and to successfully designing and implementing remedial actions. Unfortunately, data available to support the preremedial design are often sparse and insufficient for accurately estimating contaminated soil volumes, resulting in significant uncertainty associated with these volume estimates. The uncertainty in the soil volume estimates significantly contributes to the uncertainty in the overall project cost estimates, especially since excavation and off-site disposal are the primary cost items in soil remedial action projects. The Army Corps of Engineers Buffalo District's experience has been that historical contaminated soil volume estimates developed under the Formerly Utilized Sites Remedial Action Program (FUSRAP) often underestimated the actual volume of subsurface contaminated soils requiring excavation during the course of a remedial activity. In response, the Buffalo District has adopted a variety of programmatic methods for addressing contaminated volume uncertainties. These include developing final status survey protocols prior to remedial design, explicitly estimating the uncertainty associated with volume estimates, investing in predesign data collection to reduce volume uncertainties, and incorporating dynamic work strategies and real-time analytics in predesign characterization and remediation activities. This paper describes some of these experiences in greater detail, drawing from the knowledge gained at Ashland1, Ashland2, Linde, and Rattlesnake Creek. In the case of Rattlesnake Creek, these approaches provided the Buffalo District with an accurate predesign contaminated volume estimate and resulted in one of the first successful FUSRAP fixed-price remediation contracts for the Buffalo District.

  1. Geometry modeling and grid generation using 3D NURBS control volume

    Science.gov (United States)

    Yu, Tzu-Yi; Soni, Bharat K.; Shih, Ming-Hsin

    1995-01-01

    The algorithms for volume grid generation using NURBS geometric representation are presented. The parameterization algorithm is enhanced to yield a desired physical distribution on the curve, surface and volume. This approach bridges the gap between CAD surface/volume definition and surface/volume grid generation. Computational examples associated with practical configurations have shown the utilization of these algorithms.

  2. Left ventricle endocardium segmentation for cardiac CT volumes using an optimal smooth surface

    Science.gov (United States)

    Zheng, Yefeng; Georgescu, Bogdan; Vega-Higuera, Fernando; Comaniciu, Dorin

    2009-02-01

    We recently proposed a robust heart chamber segmentation approach based on marginal space learning. In this paper, we focus on improving the LV endocardium segmentation accuracy by searching for an optimal smooth mesh that tightly encloses the whole blood pool. The refinement procedure is formulated as an optimization problem: maximizing the surface smoothness under the tightness constraint. The formulation is a convex quadratic programming problem, therefore has a unique global optimum and can be solved efficiently. Our approach has been validated on the largest cardiac CT dataset (457 volumes from 186 patients) ever reported. Compared to our previous work, it reduces the mean point-to-mesh error from 1.13 mm to 0.84 mm (22% improvement). Additionally, the system has been extensively tested on a dataset with 2000+ volumes without any major failure.

  3. REVIEW OF THE NEGOTIATION OF THE MODEL PROTOCOL ADDITIONAL TO THE AGREEMENT(S) BETWEEN STATE(S) AND THE INTERNATIONAL ATOMIC ENERGY AGENCY FOR THE APPLICATION OF SAFEGUARDS, INFCIRC/540 (Corrected) VOLUME III/III, IAEA COMMITTEE 24, DEVELOPMENT OF INFCIRC/540, ARTICLE-BY-ARTICLE REVIEW (1996-1997).

    Energy Technology Data Exchange (ETDEWEB)

    Rosenthal, M.D.; Houck, F.

    2010-01-01

    In this section of the report, the development of INFCIRC/540 is traced by a compilation of citations from the IAEA documents presented to the Board of Governors and the records of discussions in the Board that took place prior to the establishment of Committee 24 as well as the documents and discussions of that committee. The evolution of the text is presented separately for each article or, for the more complex articles, for each paragraph or group of paragraphs of the article. This section covers all articles, including those involving no issues. Background, issues, interpretations and conclusions, which were addressed in Volumes I, II, and III are not repeated here. The comments by states that are included are generally limited to objections and suggested changes. Requests for clarification or elaboration have been omitted, although it is recognized that such comments were sometimes veiled objections.

  4. Effect of tellurium addition on the physical properties of germanium selenide glassy semiconductors

    Science.gov (United States)

    Sharma, Pankaj; Katyal, S. C.

    2008-10-01

    Effect of tellurium (Te) addition on the physical properties, density ( ρ), molar volume ( Vm), compactness ( δ), cohesive energy (CE), coordination number ( m), lone pair electrons ( L) and glass transition temperature ( Tg) of Ge 10Se 90-xTe x ( x=0, 10, 20, 30, 40, 50) bulk glassy alloy has been investigated. The density of the glassy alloys has been found to increase with the increasing Te content. The molar volume and compactness of the structure of the glass, determined from measured density of the glass, have been found to increase with the increase of Te content. The CE of the investigated samples has been calculated using the chemical bond approach (CBA) and is correlated with decrease in optical band gap with the increase of Te content. The glass transition temperature has been estimated using Tichy-Ticha approach and found to increase with the increase of Te content. This has been observed that the estimated glass transition temperature using Tichy-Ticha approach is not consistent with experimental results.

  5. Effect of tellurium addition on the physical properties of germanium selenide glassy semiconductors

    Energy Technology Data Exchange (ETDEWEB)

    Sharma, Pankaj [Department of Physics, Jaypee University of Information Technology, Waknaghat, Solan, H.P. 173215 (India)], E-mail: pankaj.sharma@juit.ac.in; Katyal, S.C. [Department of Physics, Jaypee University of Information Technology, Waknaghat, Solan, H.P. 173215 (India)

    2008-10-01

    Effect of tellurium (Te) addition on the physical properties, density ({rho}), molar volume (V{sub m}), compactness ({delta}), cohesive energy (CE), coordination number (m), lone pair electrons (L) and glass transition temperature (T{sub g}) of Ge{sub 10}Se{sub 90-x}Te{sub x} (x=0, 10, 20, 30, 40, 50) bulk glassy alloy has been investigated. The density of the glassy alloys has been found to increase with the increasing Te content. The molar volume and compactness of the structure of the glass, determined from measured density of the glass, have been found to increase with the increase of Te content. The CE of the investigated samples has been calculated using the chemical bond approach (CBA) and is correlated with decrease in optical band gap with the increase of Te content. The glass transition temperature has been estimated using Tichy-Ticha approach and found to increase with the increase of Te content. This has been observed that the estimated glass transition temperature using Tichy-Ticha approach is not consistent with experimental results.

  6. Tumor-to-breast volume ratio as measured on MRI: a possible predictor of breast-conserving surgery versus mastectomy.

    Science.gov (United States)

    Faermann, Renata; Sperber, Fani; Schneebaum, Schlomo; Barsuk, Daphna

    2014-02-01

    The surgical approach to breast cancer changed dramatically in the past 20 years. The surgical objective today is to remove the tumor, ensuring negative margins and good cosmetic results, and preserving the breast when possible. Magnetic resonance imaging of the breast has become an essential imaging tool prior to surgery, diagnosing additional tumors and assessing tumor extent. Tumor-to-breast volume ratio, an important predictor of breast conservation, can be measured with MRI and may change the surgical decision. To measure the tumor-to-breast volume ratio using MRI in order to assess whether there is a correlation between this ratio and the type of surgery selected (breast-conserving or mastectomy). The volumes of the tumor and the breast and the tumor-to-breast volume ratio were retrospectively calculated using preoperative breast MRI in 76 patients who underwent breast-conserving surgery or mastectomy. Breast-conserving surgery (lumpectomy) was performed in 64 patients and mastectomy in 12. The average tumor-to-breast volume ratio was 0.06 (6%) in the lumpectomy group and 0.30 (30%) in the mastectomy group (P < 0.0001). The tumor-to-breast volume ratio correlated with the type of surgery. As measured on MRI, this ratio is an accurate means of determining the type of surgery best suited for a given patient. It is recommended that MRI-determined tumor-to-breast volume ratio become part of the surgical planning protocol for patients diagnosed with breast cancer.

  7. 78 FR 49411 - Denial of Petitions for Reconsideration of Regulation of Fuels and Fuel Additives: 2013 Biomass...

    Science.gov (United States)

    2013-08-14

    ... Fuel Additives: 2013 Biomass-Based Diesel Renewable Fuel Volume Final Rule AGENCY: Environmental... entitled Regulation of Fuels and Fuel Additives: 2013 Biomass-Based Diesel Renewable Fuel Volume. DATES...(o)(2)(B)(ii) of the Clean Air Act requires that EPA determine the applicable volume of...

  8. Subgroup finding via Bayesian additive regression trees.

    Science.gov (United States)

    Sivaganesan, Siva; Müller, Peter; Huang, Bin

    2017-03-09

    We provide a Bayesian decision theoretic approach to finding subgroups that have elevated treatment effects. Our approach separates the modeling of the response variable from the task of subgroup finding and allows a flexible modeling of the response variable irrespective of potential subgroups of interest. We use Bayesian additive regression trees to model the response variable and use a utility function defined in terms of a candidate subgroup and the predicted response for that subgroup. Subgroups are identified by maximizing the expected utility where the expectation is taken with respect to the posterior predictive distribution of the response, and the maximization is carried out over an a priori specified set of candidate subgroups. Our approach allows subgroups based on both quantitative and categorical covariates. We illustrate the approach using simulated data set study and a real data set. Copyright © 2017 John Wiley & Sons, Ltd.

  9. Analysis of Partial Volume Effects on Accurate Measurement of the Hippocampus Volume

    Institute of Scientific and Technical Information of China (English)

    Maryam Hajiesmaeili; Jamshid Dehmeshki; Tim Ellis

    2014-01-01

    Hippocampal volume loss is an important biomarker in distinguishing subjects with Alzheimer’s disease (AD) and its measurement in magnetic resonance images (MRI) is influenced by partial volume effects (PVE). This paper describes a post-processing approach to quantify PVE for correction of the hippocampal volume by using a spatial fuzzyC-means (SFCM) method. The algorithm is evaluated on a dataset of 20 T1-weighted MRI scans sampled at two different resolutions. The corrected volumes for left and right hippocampus (HC) which are 23% and 18% for the low resolution and 6% and 5% for the high resolution datasets, respectively are lower than hippocampal volume results from manual segmentation. Results show the importance of applying this technique in AD detection with low resolution datasets.

  10. An investigation of the effect of pit latrine additives on VIP latrine ...

    African Journals Online (AJOL)

    2015-07-04

    Jul 4, 2015 ... additives claim that by addition of this product to pit content, accumulation rate and pit content volume can be reduced, .... quantify the effect of natural degradation and dehydration of pit latrine ... through the toilet pedestal.

  11. Volume regulation in epithelia

    DEFF Research Database (Denmark)

    Larsen, Erik Hviid; Hoffmann, Else Kay

    2016-01-01

    function of iso-osmotic fluid transport that depends on Na+ recirculation. The causative relationship is discussed for a fluid-absorbing and a fluid-secreting epithelium of which the Na+ recirculation mechanisms have been identified. A large number of transporters and ion channels involved in cell volume...... regulation are cloned. The volume-regulated anion channel (VRAC) exhibiting specific electrophysiological characteristics seems exclusive to serve cell volume regulation. This is contrary to K+ channels as well as cotransporters and exchange mechanisms that may serve both transepithelial transport and cell...

  12. Towards the Amplituhedron Volume

    CERN Document Server

    Ferro, Livia; Orta, Andrea; Parisi, Matteo

    2015-01-01

    It has been recently conjectured that scattering amplitudes in planar N=4 super Yang-Mills are given by the volume of the (dual) amplituhedron. In this paper we show some interesting connections between the tree-level amplituhedron and a special class of differential equations. In particular we demonstrate how the amplituhedron volume for NMHV amplitudes is determined by these differential equations. The new formulation allows for a straightforward geometric description, without any reference to triangulations. Finally we discuss possible implications for volumes related to generic N^kMHV amplitudes.

  13. The Additive Hazard Mixing Models

    Institute of Scientific and Technical Information of China (English)

    Ping LI; Xiao-liang LING

    2012-01-01

    This paper is concerned with the aging and dependence properties in the additive hazard mixing models including some stochastic comparisons.Further,some useful bounds of reliability functions in additive hazard mixing models are obtained.

  14. ADDITIVES USED TO OBTAIN FOOD

    Directory of Open Access Journals (Sweden)

    Dorina Ardelean

    2012-01-01

    Full Text Available Use of food additives in food is determined by the growth of contemporary food needs of the world population. Additives used in food, both natural and artificial ones, contribute to: improving the organoleptic characteristics and to preserve the food longer, but we must not forget that all these additives should not be found naturally in food products. Some of these additives are not harmful and human pests in small quantities, but others may have harmful effects on health.

  15. Jail Removal Cost Study. Volume 2.

    Science.gov (United States)

    Illinois Univ., Champaign. Community Research Center.

    This second volume of the jail removal cost study provides a detailed report of the study findings which examine the costs, experiences, and ramifications of removing children from adult jails and lockups. The foreword supplies background information and hypothetical removal cost estimates. The approach used to conduct the jail removal cost study…

  16. Finite volume renormalization scheme for fermionic operators

    Energy Technology Data Exchange (ETDEWEB)

    Monahan, Christopher; Orginos, Kostas [JLAB

    2013-11-01

    We propose a new finite volume renormalization scheme. Our scheme is based on the Gradient Flow applied to both fermion and gauge fields and, much like the Schr\\"odinger functional method, allows for a nonperturbative determination of the scale dependence of operators using a step-scaling approach. We give some preliminary results for the pseudo-scalar density in the quenched approximation.

  17. Pulse volume discharges in high pressure gases

    Science.gov (United States)

    Yamshchikov, V. A.

    2015-11-01

    New approach for suppression of plasma inhomogeneities and instabilities in the volume self-sustained discharge is offered. The physical model is offered and conditions of obtaining extremely homogeneous self-sustained discharge are defined (with full suppression of plasma inhomogeneity and instability). Results of calculations agree with experiments.

  18. Detergent Additive for Lubricating Oils,

    Science.gov (United States)

    The Russian patent pertains to a method of producing additives for lubricating oils . A method is known for producing an antiwear additive for... lubricating oils by processing phenols with phosphorus oxychloride, phosphoric acid esters are obtained. In order to give the additive detergent properties

  19. Free volume under shear

    Science.gov (United States)

    Maiti, Moumita; Vinutha, H. A.; Sastry, Srikanth; Heussinger, Claus

    2015-10-01

    Using an athermal quasistatic simulation protocol, we study the distribution of free volumes in sheared hard-particle packings close to, but below, the random-close packing threshold. We show that under shear, and independent of volume fraction, the free volumes develop features similar to close-packed systems — particles self-organize in a manner as to mimick the isotropically jammed state. We compare athermally sheared packings with thermalized packings and show that thermalization leads to an erasure of these structural features. The temporal evolution in particular the opening-up and the closing of free-volume patches is associated with the single-particle dynamics, showing a crossover from ballistic to diffusive behavior.

  20. Integers annual volume 2013

    CERN Document Server

    Landman, Bruce

    2014-01-01

    ""Integers"" is a refereed online journal devoted to research in the area of combinatorial number theory. It publishes original research articles in combinatorics and number theory. This work presents all papers of the 2013 volume in book form.

  1. Environmental chemistry: Volume A

    Energy Technology Data Exchange (ETDEWEB)

    Yen, T.F.

    1999-08-01

    This is an extensive introduction to environmental chemistry for engineering and chemical professionals. The contents of Volume A include a brief review of basic chemistry prior to coverage of litho, atmo, hydro, pedo, and biospheres.

  2. Left ventricular pressure-volume diagrams and end-systolic pressure-volume relations in human beings.

    Science.gov (United States)

    McKay, R G; Aroesty, J M; Heller, G V; Royal, H; Parker, J A; Silverman, K J; Kolodny, G M; Grossman, W

    1984-02-01

    Assessment of left ventricular pressure-volume relations serially in response to altered loading conditions and heart rate has been difficult to achieve with contrast ventriculography. Accordingly, to study changing pressure-volume relations during altered loading and heart rate, left ventricular pressure and radionuclide absolute volume curves (obtained using a counts-based method with attenuation factor corrections) were recorded in 20 patients. Ventricular pressure and radionuclide volume curves were digitized and synchronized to end-diastole, and pressure-volume plots were subsequently constructed from 32 pressure-volume coordinates throughout the cardiac cycle. In all patients, the correlation between radionuclide absolute volumes and angiographic ventricular volumes was r = 0.92. In 10 patients in whom both radionuclide and angiographic pressure-volume diagrams were constructed, the agreement between the two methods was excellent. With this method, end-systolic pressure-volume relations were examined during altered left ventricular loading conditions, pacing-induced incremental increases in heart rate and pacing-induced ischemia. Using pharmacologically induced changes in left ventricular loading conditions, the slope and volume intercept of the end-systolic pressure-volume line could be calculated as a means of assessing basal contractility. During pacing-induced tachycardia, the slope and volume intercept of the end-systolic pressure-volume line could be calculated to quantify the Treppe effect and assess negative inotropic changes secondary to ischemia. This study supports the validity of using serial recordings of left ventricular pressure and radionuclide volumes to assess left ventricular pressure-volume relations, and indicates that this approach may be useful in the analysis of end-systolic pressure-volume relations in patients.

  3. Left ventricular pressure-volume diagrams and end-systolic pressure-volume relations in human beings

    Energy Technology Data Exchange (ETDEWEB)

    McKay, R.G.; Aroesty, J.M.; Heller, G.V.; Royal, H.; Parker, J.A.; Silverman, K.J.; Kolodny, G.M.; Grossman, W.

    1984-02-01

    Assessment of left ventricular pressure-volume relations serially in response to altered loading conditions and heart rate has been difficult to achieve with contrast ventriculography. Accordingly, to study changing pressure-volume relations during altered loading and heart rate, left ventricular pressure and radionuclide absolute volume curves (obtained using a counts-based method with attenuation factor corrections) were recorded in 20 patients. Ventricular pressure and radionuclide volume curves were digitized and synchronized to end-diastole, and pressure-volume plots were subsequently constructed from 32 pressure-volume coordinates throughout the cardiac cycle. In all patients, the correlation between radionuclide absolute volumes and angiographic ventricular volumes was r . 0.92. In 10 patients in whom both radionuclide and angiographic pressure-volume diagrams were constructed, the agreement between the two methods was excellent. With this method, end-systolic pressure-volume relations were examined during altered left ventricular loading conditions, pacing-induced incremental increases in heart rate and pacing-induced ischemia. Using pharmacologically induced changes in left ventricular loading conditions, the slope and volume intercept of the end-systolic pressure-volume line could be calculated as a means of assessing basal contractility. During pacing-induced tachycardia, the slope and volume intercept of the end-systolic pressure-volume line could be calculated to quantify the Treppe effect and assess negative inotropic changes secondary to ischemia. This study supports the validity of using serial recordings of left ventricular pressure and radionuclide volumes to assess left ventricular pressure-volume relations, and indicates that this approach may be useful in the analysis of end-systolic pressure-volume relations in patients.

  4. Time-Adjusted Internal Target Volume: A Novel Approach Focusing on Heterogeneity of Tumor Motion Based on 4-Dimensional Computed Tomography Imaging for Radiation Therapy Planning of Lung Cancer

    Energy Technology Data Exchange (ETDEWEB)

    Nishibuchi, Ikuno [Department of Radiation Oncology, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima (Japan); Department of Radiation Oncology, Hiroshima Prefectural Hospital, Hiroshima (Japan); Kimura, Tomoki, E-mail: tkkimura@hiroshima-u.ac.jp [Department of Radiation Oncology, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima (Japan); Nakashima, Takeo; Ochi, Yusuke [Division of Radiation Therapy, Hiroshima University Hospital, Hiroshima (Japan); Takahashi, Ippei; Doi, Yoshiko; Kenjo, Masahiro; Kaneyasu, Yuko; Ozawa, Syuichi; Murakami, Yuji [Department of Radiation Oncology, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima (Japan); Wadasaki, Koichi [Department of Radiation Oncology, Hiroshima Prefectural Hospital, Hiroshima (Japan); Nagata, Yasushi [Department of Radiation Oncology, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima (Japan)

    2014-08-01

    Purpose: To consider nonuniform tumor motion within the internal target volume (ITV) by defining time-adjusted ITV (TTV), a volume designed to include heterogeneity of tumor existence on the basis of 4-dimensional computed tomography (4D-CT). Methods and Materials: We evaluated 30 lung cancer patients. Breath-hold CT (BH-CT) and free-breathing 4D-CT scans were acquired for each patient. The tumors were manually delineated using a lung CT window setting (window, 1600 HU; level, −300 HU). Tumor in BH-CT images was defined as gross tumor volume (GTV), and the sum of tumors in 4D-CT images was defined as ITV-4D. The TTV images were generated from the 4D-CT datasets, and the tumor existence probability within ITV-4D was calculated. We calculated the TTV{sub 80} value, which is the percentage of the volume with a tumor existence probability that exceeded 80% on ITV-4D. Several factors that affected the TTV{sub 80} value, such as the ITV-4D/GTV ratio or tumor centroid deviation, were evaluated. Results: Time-adjusted ITV images were acquired for all patients, and tumor respiratory motion heterogeneity was visualized. The median (range) ITV-4D/GTV ratio and median tumor centroid deviation were 1.6 (1.0-4.1) and 6.3 mm (0.1-30.3 mm), respectively. The median TTV{sub 80} value was 43.3% (2.9-98.7%). Strong correlations were observed between the TTV{sub 80} value and the ITV-4D/GTV ratio (R=−0.71) and tumor centroid deviation (R=−0.72). The TTV images revealed the tumor motion pattern features within ITV. Conclusions: The TTV images reflected nonuniform tumor motion, and they revealed the tumor motion pattern features, suggesting that the TTV concept may facilitate various aspects of radiation therapy planning of lung cancer while incorporating respiratory motion in the future.

  5. Characterizing the kinetics of volume recovery in glasses by instantaneous temperature-jump experiments

    Energy Technology Data Exchange (ETDEWEB)

    Lagasse, R.R. (Sandia National Labs., Albuquerque, NM); Cohen, R.E.; Letton, A.

    1982-03-01

    This article proposes a temperature-jump (T-jump) approach for characterizing the kinetics of volume recovery in glassy materials. The kinetic characterization is based on the Kovacs-Aklonis model. This incorporates a retardation-time spectrum which shifts according to both the temperature and the instantaneous volume. The proposed experiments involve measuring the change in recovery rate caused by an abrupt temperature jump. Although an analogous procedure has been used to determine the activation energy for linear viscoelastic creep, the analysis for volume recovery is complicated by its inherent nonlinearity. Nevertheless, accounting for the nonlinearity by a reduction of the time scale permits the T-jump results to be analyzed. In particular, the T-jump approach can be used to: (i) test a particular functional form for the shift factor; and (ii) determine the previously unmeasurable parameter x, which defines the relative importance of the temperature dependence and the volume dependence in this function. In addition, numerical simulations indicate that the proposed method can be implemented in the laboratory. 7 figures.

  6. ICONES ORCHIDACEARUM MALAYENSIUM: ADDIT AMENTA

    Directory of Open Access Journals (Sweden)

    J. J. SMITH

    2015-11-01

    Full Text Available A few weeks after the publication of the final instalment of the late Dr J. J. Smith's "Icones Orchidacearum Malayensium," volume 2 (Bulletin du Jardin Botanique de Buitenzorg, Serie III, Supplement: Volume 3. 1949, a dozen more plates of this work were submitted to the Herbarium at Bogor (Buitenzorg from the author's estate. As inclusion in the aforementioned volume, which was definitely closed last year, appeared undersirable for technical reasons, these addi- tional plates are now issued separately from the "Icones." They still represent an undoubtedly valuable contribution to the correct understand- ing of no less than 54 species of orchids all (except one previously de- scribed by Dr Smith as new. The explanations were all prepared by the author himself. If the present plates had been incorporated in the main work (which ends with plate 176 in their proper sequence, they would have been numbered 178-189. Of plate 177 only the explanation could be found; the plate itself is missing. The species represented by it are: Liparis arcuata J. J. S., L. endertii J. J. S., L. lycopodioides J. J. S., and L. biglobulifera J.J. S.

  7. Reachable volume RRT

    KAUST Repository

    McMahon, Troy

    2015-05-01

    © 2015 IEEE. Reachable volumes are a new technique that allows one to efficiently restrict sampling to feasible/reachable regions of the planning space even for high degree of freedom and highly constrained problems. However, they have so far only been applied to graph-based sampling-based planners. In this paper we develop the methodology to apply reachable volumes to tree-based planners such as Rapidly-Exploring Random Trees (RRTs). In particular, we propose a reachable volume RRT called RVRRT that can solve high degree of freedom problems and problems with constraints. To do so, we develop a reachable volume stepping function, a reachable volume expand function, and a distance metric based on these operations. We also present a reachable volume local planner to ensure that local paths satisfy constraints for methods such as PRMs. We show experimentally that RVRRTs can solve constrained problems with as many as 64 degrees of freedom and unconstrained problems with as many as 134 degrees of freedom. RVRRTs can solve problems more efficiently than existing methods, requiring fewer nodes and collision detection calls. We also show that it is capable of solving difficult problems that existing methods cannot.

  8. Estimation of tephra volumes from sparse and incompletely observed deposit thicknesses

    Science.gov (United States)

    Green, Rebecca M.; Bebbington, Mark S.; Jones, Geoff; Cronin, Shane J.; Turner, Michael B.

    2016-04-01

    We present a Bayesian statistical approach to estimate volumes for a series of eruptions from an assemblage of sparse proximal and distal tephra (volcanic ash) deposits. Most volume estimates are of widespread tephra deposits from large events using isopach maps constructed from observations at exposed locations. Instead, we incorporate raw thickness measurements, focussing on tephra thickness data from cores extracted from lake sediments and through swamp deposits. This facilitates investigation into the dispersal pattern and volume of tephra from much smaller eruption events. Given the general scarcity of data and the physical phenomena governing tephra thickness attenuation, a hybrid Bayesian-empirical tephra attenuation model is required. Point thickness observations are modeled as a function of the distance and angular direction of each location. The dispersal of tephra from larger well-estimated eruptions are used as leverage for understanding the smaller unknown events, and uncertainty in thickness measurements can be properly accounted for. The model estimates the wind and site-specific effects on the tephra deposits in addition to volumes. Our technique is exemplified on a series of tephra deposits from Mt Taranaki (New Zealand). The resulting estimates provide a comprehensive record suitable for supporting hazard models. Posterior mean volume estimates range from 0.02 to 0.26 km 3. Preliminary examination of the results suggests a size-predictable relationship.

  9. Sequential unilateral lung volume reduction for emphysema - Stretching the benefit.

    Science.gov (United States)

    Khorramnia, Sadie; Holsworth, Lynda; Mestitz, Hugh; Westall, Glen P; Williams, Trevor J; Gooi, Julian H; Snell, Gregory I

    2017-01-01

    Bronchoscopic Lung Volume Reduction (BLVR) and Surgical Lung Volume Reduction (SLVR) and are two different approaches used to remodel severely emphysematous lungs to improve lung function and quality-of-life. We present a case initially referred for lung transplantation, where sequential left upper lobe BLVR and 7 years later right upper lobe SLVR, providing enduring physiological and functional improvement. The potential for sustained benefit via sequential unilateral lung volume reduction is under-appreciated.

  10. The Persistence of the Large Volumes in Black Holes

    CERN Document Server

    Ong, Yen Chin

    2015-01-01

    Classically, black holes admit maximal interior volumes that grow asymptotically linearly in time. We show that such volumes remain large when Hawking evaporation is taken into account. Even if a charged black hole approaches the extremal limit during this evolution, its volume continues to grow; although an exactly extremal black hole does not have a "large interior". We clarify this point and discuss the implications of our results to the information loss and firewall paradoxes.

  11. [Intolerance to food additives: an update].

    Science.gov (United States)

    Cardinale, F; Mangini, F; Berardi, M; Sterpeta Loffredo, M; Chinellato, I; Dellino, A; Cristofori, F; Di Domenico, F; Mastrototaro, M F; Cappiello, A; Centoducati, T; Carella, F; Armenio, L

    2008-12-01

    Contrary to common believing, the prevalence of the intolerance to food additives in the general population is rather low. Nowadays many doubts persist with regard both to the pathogenetic mechanisms and to the clinical and diagnostic aspects in this field. Symptoms due to, or exacerbated from, food additives usually involve non-IgE-mediate mechanisms (pseudo-allergic reactions, PAR) and are usually less severe of those induced by food allergy. The most frequent clinical feature of the intolerance to food additives still remains the urticaria-angioedema syndrome, although these substances are really involved only in a minority of patients. Other possible clinical features include anaphylaxis, atopic eczema, behaviour disturbances, asthma and non-allergic rhinitis. The diagnostic approach consists in diary cards, reporting symptoms and food habits, elimination diet and double blinded placebo-controlled oral challenge with suspected additives. However, such procedure still remains poorly standardized and numerous uncertainties persist with regard to optimal conditions for performing and interpret the challenge results. The therapeutic approach consists in the exclusion of foods and products containing the additive involved, and, in patients not compliant to the diet, in treatment with symptomatic drugs.

  12. Recovery Efficiency Test Project Phase 2 activity report, Volume 1

    Energy Technology Data Exchange (ETDEWEB)

    Overbey, W.K. Jr.; Salamy, S.P.; Locke, C.D.

    1989-02-01

    The purpose of Phase II operations of the Recovery Efficiency Test Project is to enhance the natural production of the well and evaluate the relative improvement as a function of the type of stimulation conducted. Another purpose is to compare the stimulated production performance of the horizontal well with vertical wells in the field. The objectives considered for Phase II operations and plans were: (1) Develop a rationale for a systematic approach to designing stimulations for the well. (2) Conduct a series of stimulations designed to optimize the fluids, injection rates, proppant volumes and general approach to stimulating a horizontal well with similar geologic conditions. (3) Develop and test a method or methods for determining the geometry of stimulation-induced fractures. (4) Conduct tests and analyze the results to determine the efficiency of stimulation operations. The technical approach pursued in developing plans to accomplish three objectives was to: (1) Review the data needs for all objectives and obtain that data first. (2) Identify the operating geologic, geomechanical, and reservoir parameters that need additional clarification or definition. (3) Investigate existing models which could be used to plan or evaluate stimulation on the well and the reservoir. (4) Plan for analysis and verification of models and approaches.

  13. Complementary and Alternative Approaches to Health

    Science.gov (United States)

    ... Fight Stress / Stress and Your Brain / Can Prolonged Stress Affect Whether Breast Cancer Returns? / Complementary and Alternative Approaches to Health Winter 2008 Issue: Volume 3 Number 1 Page ...

  14. Effect of Additives on the Physicochemical and Drug Release ...

    African Journals Online (AJOL)

    Erah

    diffusion method with and without additives (polyethylene glycol 6000, polyvinyl pyrrolidone, β cyclodextrin .... (ml) ratio. Appropriately diluted samples were filtered through Whatman filter paper no. 41(pore size 25 ... after one mechanical tap and tap volume was measured after ..... and surface area changes in compacted.

  15. Intraday seasonalities and nonstationarity of trading volume in financial markets: Collective features.

    Science.gov (United States)

    Graczyk, Michelle B; Duarte Queirós, Sílvio M

    2017-01-01

    Employing Random Matrix Theory and Principal Component Analysis techniques, we enlarge our work on the individual and cross-sectional intraday statistical properties of trading volume in financial markets to the study of collective intraday features of that financial observable. Our data consist of the trading volume of the Dow Jones Industrial Average Index components spanning the years between 2003 and 2014. Computing the intraday time dependent correlation matrices and their spectrum of eigenvalues, we show there is a mode ruling the collective behaviour of the trading volume of these stocks whereas the remaining eigenvalues are within the bounds established by random matrix theory, except the second largest eigenvalue which is robustly above the upper bound limit at the opening and slightly above it during the morning-afternoon transition. Taking into account that for price fluctuations it was reported the existence of at least seven significant eigenvalues-and that its autocorrelation function is close to white noise for highly liquid stocks whereas for the trading volume it lasts significantly for more than 2 hours -, our finding goes against any expectation based on those features, even when we take into account the Epps effect. In addition, the weight of the trading volume collective mode is intraday dependent; its value increases as the trading session advances with its eigenversor approaching the uniform vector as well, which corresponds to a soar in the behavioural homogeneity. With respect to the nonstationarity of the collective features of the trading volume we observe that after the financial crisis of 2008 the coherence function shows the emergence of an upset profile with large fluctuations from that year on, a property that concurs with the modification of the average trading volume profile we noted in our previous individual analysis.

  16. Eddy damping effect of additional conductors in superconducting levitation systems

    Energy Technology Data Exchange (ETDEWEB)

    Jiang, Zhao-Fei; Gou, Xiao-Fan, E-mail: xfgou@hhu.edu.cn

    2015-12-15

    Highlights: • In this article, for the eddy current damper attached to the HTSC, we • quantitatively investigated the damping coefficient c, damping ratio, Joule heating of the copper damper, and the vibration frequency of the PM as well. • presented four different arrangements of the copper damper, and comparatively studied their damping effects and Joule heating, and finally proposed the most advisable arrangement. - Abstract: Passive superconducting levitation systems consisting of a high temperature superconductor (HTSC) and a permanent magnet (PM) have demonstrated several fascinating applications such as the maglev system, flywheel energy storage. Generally, for the HTSC–PM levitation system, the HTSC with higher critical current density J{sub c} can obtain larger magnetic force to make the PM levitate over the HTSC (or suspended below the HTSC), however, the process of the vibration of the levitated PM, provides very limited inherent damping (essentially hysteresis). To improve the dynamic stability of the levitated PM, eddy damping of additional conductors can be considered as the most simple and effective approach. In this article, for the HTSC–PM levitation system with an additional copper damper attached to the HTSC, we numerically and comprehensively investigated the damping coefficient c, damping ratio, Joule heating of the copper damper, and the vibration frequency of the PM as well. Furthermore, we comparatively studied four different arrangements of the copper damper, on the comprehensive analyzed the damping effect, efficiency (defined by c/V{sub Cu}, in which V{sub Cu} is the volume of the damper) and Joule heating, and finally presented the most advisable arrangement.

  17. Effect of Nano Oil Additive Proportions on Friction and Wear Performance of Automotive Materials

    Directory of Open Access Journals (Sweden)

    A. Vadiraj

    2012-03-01

    Full Text Available The effect of nano boric acid and nano copper based engine and transmission oil additives in different volume ratios (1:10, 2:10, and 3:10 on friction and wear performance of cast iron and case carburized gear steel has been investigated. The results show that coefficient of friction increases with increase in volume ratio of engine oil additives and decreases with increasing in volume ratio of transmission oil additives. Cast iron substrate shows higher wear damage than case carburized gear steel. Nano copper additive with crystalline atomic structure shows more severe three body wear compared to boric acid with layered lattice structure.

  18. Coyote Papers: The University of Arizona Working Papers in Linguistics, Volume 11. Special Volume on Native American Languages.

    Science.gov (United States)

    Weinberg, Jessica P., Ed.; O'Bryan, Erin L., Ed.; Moll, Laura A., Ed.; Haugan, Jason D., Ed.

    The five papers included in this volume approach the study of American Indian languages from a diverse array of methodological and theoretical approaches to linguistics. Two papers focus on approaches that come from the applied linguistics tradition, emphasizing ethnolinguistics and discourse analysis: Sonya Bird's paper "A Cross Cultural Look at…

  19. Challenges in Additive Manufacturing of Alumina

    Science.gov (United States)

    Gonzalez, Hugo

    Additive manufacturing is seen by many as the holy grail of manufacturing, the ability to produce parts nearly autonomously. Adding material rather than removing it would eliminate the need for expensive resources and machining. The recent expiration of key 3D printing patents has led to many advances in the field and has dramatically lowered the prices of 3D printers, making them accessible to the average individual. The one area where additive manufacturing is still in its infancy is in ceramics. Ceramic materials have advantages over polymers and metals such as corrosion resistance, insulating behavior, high stiffness and high temperature stability that make them attractive in industries such as aerospace, medical, and electronics. Processing and machining ceramics however is difficult and expensive as it requires high temperature furnaces and diamond tooling. There are currently two companies that produce printers capable of printing technical ceramics, Lithoz in Germany and 3D Ceram in France. The issue is that both of these printers retail for over $100,000. The work in this thesis intends to show the challenges associated with setting up a ceramic 3D printer at a fraction of that cost for 3D printing of alumina. The first such challenge was creating a photopolymer resin that could be loaded with a large volume percent of aluminum oxide powder while maintain its curability and low viscosity. Several combinations of monomers and dispersants were evaluated before coming to the conclusion that the use of a hexanediol diacrylate monomer and quarternary ammonia acetate were the most effective in suspending volume sold loadings of over 40% while maintaining a low viscosity. The next challenge was adapting an inexpensive polymer printer to use the powder loaded resin. Various printer parameters were modified and different window coatings were implemented to create a print. The issue of the layers curing on the build area window however, proved to be difficult to

  20. Computer vision technology in log volume inspection

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    Log volume inspection is very important in forestry research and paper making engineering. This paper proposed a novel approach based on computer vision technology to cope with log volume inspection. The needed hardware system was analyzed and the details of the inspection algorithms were given. A fuzzy entropy based on image enhancement algorithm was presented for enhancing the image of the cross-section of log. In many practical applications the cross-section is often partially invisible, and this is the major obstacle for correct inspection. To solve this problem, a robust Hausdorff distance method was proposed to recover the whole cross-section. Experiment results showed that this method was efficient.

  1. Additive interaction in survival analysis

    DEFF Research Database (Denmark)

    Rod, Naja Hulvej; Lange, Theis; Andersen, Ingelise

    2012-01-01

    It is a widely held belief in public health and clinical decision-making that interventions or preventive strategies should be aimed at patients or population subgroups where most cases could potentially be prevented. To identify such subgroups, deviation from additivity of absolute effects...... implementation guide of the additive hazards model is provided in the appendix....

  2. Additive Effects on Asymmetric Catalysis.

    Science.gov (United States)

    Hong, Liang; Sun, Wangsheng; Yang, Dongxu; Li, Guofeng; Wang, Rui

    2016-03-23

    This review highlights a number of additives that can be used to make asymmetric reactions perfect. Without changing other reaction conditions, simply adding additives can lead to improved asymmetric catalysis, such as reduced reaction time, improved yield, or/and increased selectivity.

  3. Density measures and additive property

    OpenAIRE

    Kunisada, Ryoichi

    2015-01-01

    We deal with finitely additive measures defined on all subsets of natural numbers which extend the asymptotic density (density measures). We consider a class of density measures which are constructed from free ultrafilters on natural numbers and study a certain additivity property of such density measures.

  4. Enantioselective Michael Addition of Water

    NARCIS (Netherlands)

    Chen, B.S.; Resch, V.; Otten, L.G.; Hanefeld, U.

    2014-01-01

    The enantioselective Michael addition using water as both nucleophile and solvent has to date proved beyond the ability of synthetic chemists. Herein, the direct, enantioselective Michael addition of water in water to prepare important β-hydroxy carbonyl compounds using whole cells of Rhodococcus st

  5. Density measures and additive property

    OpenAIRE

    Kunisada, Ryoichi

    2015-01-01

    We deal with finitely additive measures defined on all subsets of natural numbers which extend the asymptotic density (density measures). We consider a class of density measures which are constructed from free ultrafilters on natural numbers and study a certain additivity property of such density measures.

  6. Color Addition and Subtraction Apps

    Science.gov (United States)

    Ruiz, Frances; Ruiz, Michael J.

    2015-01-01

    Color addition and subtraction apps in HTML5 have been developed for students as an online hands-on experience so that they can more easily master principles introduced through traditional classroom demonstrations. The evolution of the additive RGB color model is traced through the early IBM color adapters so that students can proceed step by step…

  7. Color Addition and Subtraction Apps

    Science.gov (United States)

    Ruiz, Frances; Ruiz, Michael J.

    2015-01-01

    Color addition and subtraction apps in HTML5 have been developed for students as an online hands-on experience so that they can more easily master principles introduced through traditional classroom demonstrations. The evolution of the additive RGB color model is traced through the early IBM color adapters so that students can proceed step by step…

  8. Calcium addition in straw gasification

    DEFF Research Database (Denmark)

    Risnes, H.; Fjellerup, Jan Søren; Henriksen, Ulrik Birk

    2003-01-01

    The present work focuses on the influence of calcium addition in gasification. The inorganic¿organic element interaction as well as the detailed inorganic¿inorganic elements interaction has been studied. The effect of calcium addition as calcium sugar/molasses solutions to straw significantly...

  9. Volumes of chain links

    CERN Document Server

    Kaiser, James; Rollins, Clint

    2011-01-01

    Agol has conjectured that minimally twisted n-chain links are the smallest volume hyperbolic manifolds with n cusps, for n at most 10. In his thesis, Venzke mentions that these cannot be smallest volume for n at least 11, but does not provide a proof. In this paper, we give a proof of Venzke's statement. The proof for n at least 60 is completely rigorous. The proof for n between 11 and 59 uses a computer calculation, and can be made rigorous for manifolds of small enough complexity, using methods of Moser and Milley. Finally, we prove that the n-chain link with 2m or 2m+1 half-twists cannot be the minimal volume hyperbolic manifold with n cusps, provided n is at least 60 or |m| is at least 8, and we give computational data indicating this remains true for smaller n and |m|.

  10. HARNESSING BIG DATA VOLUMES

    Directory of Open Access Journals (Sweden)

    Bogdan DINU

    2014-04-01

    Full Text Available Big Data can revolutionize humanity. Hidden within the huge amounts and variety of the data we are creating we may find information, facts, social insights and benchmarks that were once virtually impossible to find or were simply inexistent. Large volumes of data allow organizations to tap in real time the full potential of all the internal or external information they possess. Big data calls for quick decisions and innovative ways to assist customers and the society as a whole. Big data platforms and product portfolio will help customers harness to the full the value of big data volumes. This paper deals with technical and technological issues related to handling big data volumes in the Big Data environment.

  11. IVUS coronary volume alignment for distinct phases

    Science.gov (United States)

    Matsumoto, Monica Mitiko Soares; Lemos, Pedro Alves; Furuie, Sergio Shiguemi

    2009-02-01

    Image-based intravascular ultrasound (IVUS) cardiac phase detection allows coronary volume reconstruction in different phases. Consecutive volumes are not necessarily spatially aligned due to longitudinal movement of the catheter. Besides ordinary pullback velocity, there is a relative longitudinal movement of the heart vessel walls and the transducer, due to myocardial contraction. In this manuscript, we aim to spatially align cardiac phase coronary IVUS volumes. In addition, we want to investigate this non-linear longitudinal catheter movement. With this purpose, we have analyzed 120 simulated IVUS images and 10 real IVUS pullbacks. We implemented the following methodology. Firstly, we built IVUS volume for each distinct phase. Secondly, each IVUS volume was transformed into a parametric signal of average frame intensity. We have used these signals to make correlation in space with a reference one. Then we estimated the spatial distance between the distinct IVUS volumes and the reference. We have tested in simulated images and real examinations. We have also observed similar pattern in real IVUS examinations. This spatial alignment method is feasible and useful as a step towards dynamic studies of IVUS examination.

  12. Physical activity, fitness, and gray matter volume.

    Science.gov (United States)

    Erickson, Kirk I; Leckie, Regina L; Weinstein, Andrea M

    2014-09-01

    In this review, we explore the association among physical activity, cardiorespiratory fitness, and exercise on gray matter volume in older adults. We conclude that higher cardiorespiratory fitness levels are routinely associated with greater gray matter volume in the prefrontal cortex and hippocampus and less consistently in other regions. We also conclude that physical activity is associated with greater gray matter volume in the same regions that are associated with cardiorespiratory fitness including the prefrontal cortex and hippocampus. Some heterogeneity in the literature may be explained by effect moderation by age, stress, or other factors. Finally, we report promising results from randomized exercise interventions that suggest that the volume of the hippocampus and prefrontal cortex remain pliable and responsive to moderate intensity exercise for 6 months-1 year. Physical activity appears to be a propitious method for influencing gray matter volume in late adulthood, but additional well-controlled studies are necessary to inform public policies about the potential protective or therapeutic effects of exercise on brain volume. Copyright © 2014 Elsevier Inc. All rights reserved.

  13. Lanthanum additions and the toughness of ultra-high strength steels and the determination of appropriate lanthanum additions

    Energy Technology Data Exchange (ETDEWEB)

    Garrison, Warren M. [Department of Metallurgical Engineering and Materials Science, Carnegie Mellon University, 5000 Forbes Avenue, Pittsburgh, PA 15213 (United States)]. E-mail: wmg@andrew.cmu.edu; Maloney, James L. [Timken Company, 1835 Dueber Avenue S.W., Canton, OH 44706-0930 (United States)

    2005-08-25

    Studies of commercial heats of AF1410 steel suggest that under appropriate conditions additions of rare-earth elements can significantly enhance fracture toughness. This improvement in toughness is not due to an extremely low inclusion volume fraction but is apparently due to the formation of larger and more widely spaced inclusions. The purpose of this work is to discuss our experience in using rare-earth additions to laboratory scale vacuum induction melted and subsequently vacuum arc remelted heats of ultra-high strength steels to achieve inclusion distributions similar to those observed in commercial heats modified with lanthanum additions. The results indicate that lanthanum additions of 0.015 wt.% to low sulfur steels which have been well deoxidized using carbon-vacuum deoxidation can result in lanthanum rich inclusions which are similar in size, volume fraction and spacing to those obtained in commercially produced heats of ultra-high strength steel to which lanthanum has been added. The heat of steel to which lanthanum additions of 0.015 wt.% were made had significantly higher toughness than did the heat of the same steel in which the sulfur had been gettered as small and closely spaced particles of MnS and which had an inclusion volume fraction similar to that of the heat modified by the addition of 0.015 wt.% lanthanum. This improvement in toughness was attributed to an increase in inclusion spacing. An addition of 0.06 wt.% lanthanum was excessive. Such an addition of lanthanum resulted in a huge volume fraction of large cuboidal inclusions which primarily contain lanthanum and oxygen and which are extremely detrimental to toughness.

  14. Interactive Isogeometric Volume Visualization with Pixel-Accurate Geometry

    OpenAIRE

    Fuchs, Franz G.; Hjelmervik, Jon M.

    2014-01-01

    A recent development, called isogeometric analysis, provides a unified approach for design, analysis and optimization of functional products in industry. Traditional volume rendering methods for inspecting the results from the numerical simulations cannot be applied directly to isogeometric models. We present a novel approach for interactive visualization of isogeometric analysis results, ensuring correct, i.e., pixel-accurate geometry of the volume including its bounding surfaces. The entire...

  15. Topological Active Volumes

    Directory of Open Access Journals (Sweden)

    Barreira N

    2005-01-01

    Full Text Available The topological active volumes (TAVs model is a general model for 3D image segmentation. It is based on deformable models and integrates features of region-based and boundary-based segmentation techniques. Besides segmentation, it can also be used for surface reconstruction and topological analysis of the inside of detected objects. The TAV structure is flexible and allows topological changes in order to improve the adjustment to object's local characteristics, find several objects in the scene, and identify and delimit holes in detected structures. This paper describes the main features of the TAV model and shows its ability to segment volumes in an automated manner.

  16. CONTAMINATED SOIL VOLUME ESTIMATE TRACKING METHODOLOGY

    Energy Technology Data Exchange (ETDEWEB)

    Durham, L.A.; Johnson, R.L.; Rieman, C.; Kenna, T.; Pilon, R.

    2003-02-27

    The U.S. Army Corps of Engineers (USACE) is conducting a cleanup of radiologically contaminated properties under the Formerly Utilized Sites Remedial Action Program (FUSRAP). The largest cost element for most of the FUSRAP sites is the transportation and disposal of contaminated soil. Project managers and engineers need an estimate of the volume of contaminated soil to determine project costs and schedule. Once excavation activities begin and additional remedial action data are collected, the actual quantity of contaminated soil often deviates from the original estimate, resulting in cost and schedule impacts to the project. The project costs and schedule need to be frequently updated by tracking the actual quantities of excavated soil and contaminated soil remaining during the life of a remedial action project. A soil volume estimate tracking methodology was developed to provide a mechanism for project managers and engineers to create better project controls of costs and schedule. For the FUSRAP Linde site, an estimate of the initial volume of in situ soil above the specified cleanup guidelines was calculated on the basis of discrete soil sample data and other relevant data using indicator geostatistical techniques combined with Bayesian analysis. During the remedial action, updated volume estimates of remaining in situ soils requiring excavation were calculated on a periodic basis. In addition to taking into account the volume of soil that had been excavated, the updated volume estimates incorporated both new gamma walkover surveys and discrete sample data collected as part of the remedial action. A civil survey company provided periodic estimates of actual in situ excavated soil volumes. By using the results from the civil survey of actual in situ volumes excavated and the updated estimate of the remaining volume of contaminated soil requiring excavation, the USACE Buffalo District was able to forecast and update project costs and schedule. The soil volume

  17. Color Addition and Subtraction Apps

    Science.gov (United States)

    Ruiz, Frances; Ruiz, Michael J.

    2015-10-01

    Color addition and subtraction apps in HTML5 have been developed for students as an online hands-on experience so that they can more easily master principles introduced through traditional classroom demonstrations. The evolution of the additive RGB color model is traced through the early IBM color adapters so that students can proceed step by step in understanding mathematical representations of RGB color. Finally, color addition and subtraction are presented for the X11 colors from web design to illustrate yet another real-life application of color mixing.

  18. Large-Scale Multi-Resolution Representations for Accurate Interactive Image and Volume Operations

    KAUST Repository

    Sicat, Ronell B.

    2015-11-25

    and voxel footprints in input images and volumes. We show that the continuous pdfs encoded in the sparse pdf map representation enable accurate multi-resolution non-linear image operations on gigapixel images. Similarly, we show that sparse pdf volumes enable more consistent multi-resolution volume rendering compared to standard approaches, on both artificial and real world large-scale volumes. The supplementary videos demonstrate our results. In the standard approach, users heavily rely on panning and zooming interactions to navigate the data within the limits of their display devices. However, panning across the whole spatial domain and zooming across all resolution levels of large-scale images to search for interesting regions is not practical. Assisted exploration techniques allow users to quickly narrow down millions to billions of possible regions to a more manageable number for further inspection. However, existing approaches are not fully user-driven because they typically already prescribe what being of interest means. To address this, we introduce the patch sets representation for large-scale images. Patches inside a patch set are grouped and encoded according to similarity via a permutohedral lattice (p-lattice) in a user-defined feature space. Fast set operations on p-lattices facilitate patch set queries that enable users to describe what is interesting. In addition, we introduce an exploration framework—GigaPatchExplorer—for patch set-based image exploration. We show that patch sets in our framework are useful for a variety of user-driven exploration tasks in gigapixel images and whole collections thereof.

  19. Excluded-Volume Approximation for Supernova Matter

    CERN Document Server

    Yudin, A V

    2014-01-01

    A general scheme of the excluded-volume approximation as applied to multicomponent systems with an arbitrary degree of degeneracy has been developed. This scheme also admits an allowance for additional interactions between the components of a system. A specific form of the excluded-volume approximation for investigating supernova matter at subnuclear densities has been found from comparison with the hard-sphere model. The possibility of describing the phase transition to uniform nuclear matter in terms of the formalism under consideration is discussed.

  20. Prevalence of Food Additive Intolerance

    DEFF Research Database (Denmark)

    Madsen, Charlotte Bernhard

    1994-01-01

    estimates are questionable but may be less than 0.15%. In adults and children with reproducible, and with more subjective symptoms, such as headache and behavioural/mood change the prevalence is even lower (0.026%). Food additive intolerance is primarily found in atopic children with cutaneous symptoms.......026%. The challenged population is 81 children and adults with a history of reproducible clinical symptoms after ingestion of food additives. 4 In the Danish population study a prevalence of 1-2% is found in children age 5-16. In this study a total of 606 children mainly with atopic disease have been challenged. 5...... where the additive is aggravating an existing disease. The prevalence of food additive intolerance in children age 5-16 is 1-2%....

  1. Adverse reactions to drug additives.

    Science.gov (United States)

    Simon, R A

    1984-10-01

    There is a long list of additives used by the pharmaceutical industry. Most of the agents used have not been implicated in hypersensitivity reactions. Among those that have, only reactions to parabens and sulfites have been well established. Parabens have been shown to be responsible for rare immunoglobulin E-mediated reactions that occur after the use of local anesthetics. Sulfites, which are present in many drugs, including agents commonly used to treat asthma, have been shown to provoke severe asthmatic attacks in sensitive individuals. Recent studies indicate that additives do not play a significant role in "hyperactivity." The role of additives in urticaria is not well established and therefore the incidence of adverse reactions in this patient population is simply not known. In double-blind, placebo-controlled studies, reactions to tartrazine or additives other than sulfites, if they occur at all, are indeed quite rare for the asthmatic population, even for the aspirin-sensitive subpopulation.

  2. Estimation of feline renal volume using computed tomography and ultrasound.

    Science.gov (United States)

    Tyson, Reid; Logsdon, Stacy A; Werre, Stephen R; Daniel, Gregory B

    2013-01-01

    Renal volume estimation is an important parameter for clinical evaluation of kidneys and research applications. A time efficient, repeatable, and accurate method for volume estimation is required. The purpose of this study was to describe the accuracy of ultrasound and computed tomography (CT) for estimating feline renal volume. Standardized ultrasound and CT scans were acquired for kidneys of 12 cadaver cats, in situ. Ultrasound and CT multiplanar reconstructions were used to record renal length measurements that were then used to calculate volume using the prolate ellipsoid formula for volume estimation. In addition, CT studies were reconstructed at 1 mm, 5 mm, and 1 cm, and transferred to a workstation where the renal volume was calculated using the voxel count method (hand drawn regions of interest). The reference standard kidney volume was then determined ex vivo using water displacement with the Archimedes' principle. Ultrasound measurement of renal length accounted for approximately 87% of the variability in renal volume for the study population. The prolate ellipsoid formula exhibited proportional bias and underestimated renal volume by a median of 18.9%. Computed tomography volume estimates using the voxel count method with hand-traced regions of interest provided the most accurate results, with increasing accuracy for smaller voxel sizes in grossly normal kidneys (-10.1 to 0.6%). Findings from this study supported the use of CT and the voxel count method for estimating feline renal volume in future clinical and research studies.

  3. Wide and High Additive Manufacturing

    Energy Technology Data Exchange (ETDEWEB)

    Post, Brian K. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Roschli, Alex C. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)

    2017-03-01

    The goal of this project is to develop and demonstrate the enabling technologies for Wide and High Additive Manufacturing (WHAM). WHAM will open up new areas of U.S. manufacturing for very large tooling in support of the transportation and energy industries, significantly reducing cost and lead time. As with Big Area Additive Manufacturing (BAAM), the initial focus is on the deposition of composite materials.

  4. Introduction to the Volume.

    Science.gov (United States)

    Emihovich, Catherine; Schroder, Barbara; Panofsky, Carolyn P.

    1999-01-01

    Introduces a volume that examines the issue of critical thinking and whether or not it is culturally specific, discussing recent research on the subject. The papers focus on critical thinking and culture, historical consciousness and critical thinking, critical thinking as cultural-historical practice, culture and the development of critical…

  5. Additive manufacturing of tunable lenses

    Science.gov (United States)

    Schlichting, Katja; Novak, Tobias; Heinrich, Andreas

    2017-02-01

    Individual additive manufacturing of optical systems based on 3D Printing offers varied possibilities in design and usage. In addition to the additive manufacturing procedure, the usage of tunable lenses allows further advantages for intelligent optical systems. Our goal is to bring the advantages of additive manufacturing together with the huge potential of tunable lenses. We produced tunable lenses as a bundle without any further processing steps, like polishing. The lenses were designed and directly printed with a 3D Printer as a package. The design contains the membrane as an optical part as well as the mechanical parts of the lens, like the attachments for the sleeves which contain the oil. The dynamic optical lenses were filled with an oil. The focal length of the lenses changes due to a change of the radius of curvature. This change is caused by changing the pressure in the inside of the lens. In addition to that, we designed lenses with special structures to obtain different areas with an individual optical power. We want to discuss the huge potential of this technology for several applications. Further, an appropriate controlling system is needed. Wéll show the possibilities to control and regulate the optical power of the lenses. The lenses could be used for illumination tasks, and in the future, for individual measurement tasks. The main advantage is the individuality and the possibility to create an individual design which completely fulfills the requirements for any specific application.

  6. Clinical effects of sulphite additives.

    Science.gov (United States)

    Vally, H; Misso, N L A; Madan, V

    2009-11-01

    Sulphites are widely used as preservative and antioxidant additives in the food and pharmaceutical industries. Topical, oral or parenteral exposure to sulphites has been reported to induce a range of adverse clinical effects in sensitive individuals, ranging from dermatitis, urticaria, flushing, hypotension, abdominal pain and diarrhoea to life-threatening anaphylactic and asthmatic reactions. Exposure to the sulphites arises mainly from the consumption of foods and drinks that contain these additives; however, exposure may also occur through the use of pharmaceutical products, as well as in occupational settings. While contact sensitivity to sulphite additives in topical medications is increasingly being recognized, skin reactions also occur after ingestion of or parenteral exposure to sulphites. Most studies report a 3-10% prevalence of sulphite sensitivity among asthmatic subjects following ingestion of these additives. However, the severity of these reactions varies, and steroid-dependent asthmatics, those with marked airway hyperresponsiveness, and children with chronic asthma, appear to be at greater risk. In addition to episodic and acute symptoms, sulphites may also contribute to chronic skin and respiratory symptoms. To date, the mechanisms underlying sulphite sensitivity remain unclear, although a number of potential mechanisms have been proposed. Physicians should be aware of the range of clinical manifestations of sulphite sensitivity, as well as the potential sources of exposure. Minor modifications to diet or behaviour lead to excellent clinical outcomes for sulphite-sensitive individuals.

  7. Evaluation of certain food additives.

    Science.gov (United States)

    2015-01-01

    This report represents the conclusions of a Joint FAO/WHO Expert Committee convened to evaluate the safety of various food additives, including flavouring agents, and to prepare specifications for identity and purity. The first part of the report contains a general discussion of the principles governing the toxicological evaluation of and assessment of dietary exposure to food additives, including flavouring agents. A summary follows of the Committee's evaluations of technical, toxicological and dietary exposure data for eight food additives (Benzoe tonkinensis; carrageenan; citric and fatty acid esters of glycerol; gardenia yellow; lutein esters from Tagetes erecta; octenyl succinic acid-modified gum arabic; octenyl succinic acid-modified starch; paprika extract; and pectin) and eight groups of flavouring agents (aliphatic and alicyclic hydrocarbons; aliphatic and aromatic ethers; ionones and structurally related substances; miscellaneous nitrogen-containing substances; monocyclic and bicyclic secondary alcohols, ketones and related esters; phenol and phenol derivatives; phenyl-substituted aliphatic alcohols and related aldehydes and esters; and sulfur-containing heterocyclic compounds). Specifications for the following food additives were revised: citric acid; gellan gum; polyoxyethylene (20) sorbitan monostearate; potassium aluminium silicate; and Quillaia extract (Type 2). Annexed to the report are tables summarizing the Committee's recommendations for dietary exposures to and toxicological evaluations of all of the food additives and flavouring agents considered at this meeting.

  8. [INVITED] Lasers in additive manufacturing

    Science.gov (United States)

    Pinkerton, Andrew J.

    2016-04-01

    Additive manufacturing is a topic of considerable ongoing interest, with forecasts predicting it to have major impact on industry in the future. This paper focusses on the current status and potential future development of the technology, with particular reference to the role of lasers within it. It begins by making clear the types and roles of lasers in the different categories of additive manufacturing. This is followed by concise reviews of the economic benefits and disadvantages of the technology, current state of the market and use of additive manufacturing in different industries. Details of these fields are referenced rather than expanded in detail. The paper continues, focusing on current indicators to the future of additive manufacturing. Barriers to its development, trends and opportunities in major industrial sectors, and wider opportunities for its development are covered. Evidence indicates that additive manufacturing may not become the dominant manufacturing technology in all industries, but represents an excellent opportunity for lasers to increase their influence in manufacturing as a whole.

  9. A Research Needs Assessment for waste plastics recycling: Volume 1, Executive summary. Final report

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1994-12-01

    This first volume provides a summary of the entire project. The study utilized the talents of a large number of participants, including a significant number of peer reviewers from industrial companies, government agencies, and research institutes. in addition, an extensive analysis of relevant literature was carried out. In considering the attractiveness of recycling technologies that are alternatives to waste-to-energy combustion units, a systems approach was utilized. Collection of waste streams containing plastics, sortation, and reclamation of plastics and plastic mixtures, reprocessing or chemical conversion of the reclaimed polymers, and the applicability of the products to specific market segments have been analyzed in the study.

  10. Teaching Thermal Hydraulics & Numerical Methods: An Introductory Control Volume Primer

    Energy Technology Data Exchange (ETDEWEB)

    D. S. Lucas

    2004-10-01

    A graduate level course for Thermal Hydraulics (T/H) was taught through Idaho State University in the spring of 2004. A numerical approach was taken for the content of this course since the students were employed at the Idaho National Laboratory and had been users of T/H codes. The majority of the students had expressed an interest in learning about the Courant Limit, mass error, semi-implicit and implicit numerical integration schemes in the context of a computer code. Since no introductory text was found the author developed notes taught from his own research and courses taught for Westinghouse on the subject. The course started with a primer on control volume methods and the construction of a Homogeneous Equilibrium Model (HEM) (T/H) code. The primer was valuable for giving the students the basics behind such codes and their evolution to more complex codes for Thermal Hydraulics and Computational Fluid Dynamics (CFD). The course covered additional material including the Finite Element Method and non-equilibrium (T/H). The control volume primer and the construction of a three-equation (mass, momentum and energy) HEM code are the subject of this paper . The Fortran version of the code covered in this paper is elementary compared to its descendants. The steam tables used are less accurate than the available commercial version written in C Coupled to a Graphical User Interface (GUI). The Fortran version and input files can be downloaded at www.microfusionlab.com.

  11. Shared Communications: Volume 2. In-Depth Systems Research

    Energy Technology Data Exchange (ETDEWEB)

    Truett, LF

    2004-09-22

    This report is the second of two documents that examine the literature for actual examples of organizations and agencies that share communications resources. While the primary emphasis is on rural, intelligent transportation system (ITS) communications involving transit, examples will not be limited to rural activities, nor to ITS implementation, nor even to transit. In addition, the term ''communication'' will be broadly applied to include all information resources. The first document of this series, ''Shared Communications: Volume I. A Summary and Literature Review'', defines the meaning of the term ''shared communication resources'' and provides many examples of agencies that share resources. This document, ''Shared Communications: Volume II. In-Depth Systems Research'', reviews attributes that contributed to successful applications of the sharing communication resources concept. A few examples of each type of communication sharing are provided. Based on the issues and best practice realworld examples, recommendations for potential usage and recommended approaches for field operational tests are provided.

  12. Hippocampal subfield volumes in mood disorders.

    Science.gov (United States)

    Cao, B; Passos, I C; Mwangi, B; Amaral-Silva, H; Tannous, J; Wu, M-J; Zunta-Soares, G B; Soares, J C

    2017-01-24

    Volume reduction and shape abnormality of the hippocampus have been associated with mood disorders. However, the hippocampus is not a uniform structure and consists of several subfields, such as the cornu ammonis (CA) subfields CA1-4, the dentate gyrus (DG) including a granule cell layer (GCL) and a molecular layer (ML) that continuously crosses adjacent subiculum (Sub) and CA fields. It is known that cellular and molecular mechanisms associated with mood disorders may be localized to specific hippocampal subfields. Thus, it is necessary to investigate the link between the in vivo hippocampal subfield volumes and specific mood disorders, such as bipolar disorder (BD) and major depressive disorder (MDD). In the present study, we used a state-of-the-art hippocampal segmentation approach, and we found that patients with BD had reduced volumes of hippocampal subfields, specifically in the left CA4, GCL, ML and both sides of the hippocampal tail, compared with healthy subjects and patients with MDD. The volume reduction was especially severe in patients with bipolar I disorder (BD-I). We also demonstrated that hippocampal subfield volume reduction was associated with the progression of the illness. For patients with BD-I, the volumes of the right CA1, ML and Sub decreased as the illness duration increased, and the volumes of both sides of the CA2/3, CA4 and hippocampal tail had negative correlations with the number of manic episodes. These results indicated that among the mood disorders the hippocampal subfields were more affected in BD-I compared with BD-II and MDD, and manic episodes had focused progressive effect on the CA2/3 and CA4 and hippocampal tail.Molecular Psychiatry advance online publication, 24 January 2017; doi:10.1038/mp.2016.262.

  13. Automated three-dimensional single cell phenotyping of spindle dynamics, cell shape, and volume

    CERN Document Server

    Plumb, Kemp; Pelletier, Vincent; Kilfoil, Maria L

    2015-01-01

    We present feature finding and tracking algorithms in 3D in living cells, and demonstrate their utility to measure metrics important in cell biological processes. We developed a computational imaging hybrid approach that combines automated three-dimensional tracking of point-like features with surface determination from which cell (or nuclear) volume, shape, and planes of interest can be extracted. After validation, we applied the technique to real space context-rich dynamics of the mitotic spindle, and cell volume and its relationship to spindle length, in dividing living cells. These methods are additionally useful for automated segregation of pre-anaphase and anaphase spindle populations in budding yeast. We found that genetic deletion of the yeast kinesin-5 mitotic motor cin8 leads to large mother and daughter cells that were indistinguishable based on size, and that in those cells the spindle length becomes uncorrelated with cell size. The technique can be used to visualize and quantify tracked feature c...

  14. HEAT TRANSFER ENHANCEMENT USING LOW VOLUME CONCENTRATIONS OF Fe3O4 NANOFLUID IN CIRCULAR PIPE

    Directory of Open Access Journals (Sweden)

    BHRAMARA PANITAPU

    2014-10-01

    Full Text Available Nanofluids are emerging as one of the effective means of enhancing the heat transfer compared to the conventional heat transfer fluids due enhancement of thermophysical properties of base fluids due to addition of nanosized particles. Numerical experiments were conducted for heat transfer inside a circular pipe subjected to constant heat flux with water as base fluid. Heat transfer enhancement was studied by adding low volume concentrations, viz., 0.1 to 0.6 % of Fe3O4 magnetic nanoparticles of particle size 36 nm in water. The numerical analysis of nanofluid was performed using the single phase approach for the Reynold Number of the flow ranging from 2500 – 22000. The results show that better enhancement was observed at higher Re and at higher volume fractions. The numerical results were compared with the experimental data available in the literature.

  15. Topology Optimization for Additive Manufacturing

    DEFF Research Database (Denmark)

    Clausen, Anders

    This PhD thesis deals with the combination of topology optimization and additive man-ufacturing (AM, also known as 3D-printing). In addition to my own works, the thesis contains a broader review and assessment of the literature within the field. The thesis first presents a classification...... of the various AM technologies, a review of relevant manufacturing materials, the properties of these materials in the additively manufactured part, as well as manufacturing constraints with a potential for design optimization. Subsequently, specific topology optimization formulations relevant for the most im......-portant AM-related manufacturing constraints are presented. These constraints are di-vided into directional and non-directional constraints. Non-directional constraints include minimum/uniform length scale and a cavity constraint. It is shown that modified filter boundary conditions are required in order...

  16. Ruzsa's Constant on Additive Functions

    Institute of Scientific and Technical Information of China (English)

    Jin Hui FANG; Yong Gao CHEN

    2013-01-01

    A function f:N → R is called additive if f(mn) =f(m)+f(n) for all m,n with (m,n) =1.Let μ(x) =maxn≤x(f(n)-f(n + 1)) and v(x) =maxn≤x(f(n + 1)-f(n)).In 1979,Ruzsa proved that there exists a constant c such that for any additive function f,μ(x) ≤ cv(x2) + cf,where cf is a constant depending only on f.Denote by Raf the least such constant c.We call Raf Ruzsa's constant on additive functions.In this paper,we prove that Raf ≤ 20.

  17. Search for additional Higgs bosons

    CERN Document Server

    Meyer, Jochen; The ATLAS collaboration

    2017-01-01

    The Standard Model of particle physics is one of the most well-established theories in physics. However, it has some flaws which cannot be explained without physics beyond the Standard Model. Most of the theoretically explored extensions which provide potential solutions include further Higgs bosons in addition to the discovered resonance with the mass of about 125 GeV. This talk summarizes current efforts carried out by the ATLAS and CMS collaborations targeting at the discovery of further resonances. A variety of observables in multiple final states is studied and interpreted in terms of additional Higgs bosons predicted by selected models. Those additional bosons are not necessarily neutral, but could also be charged.

  18. Additional disulfide bonds in insulin

    DEFF Research Database (Denmark)

    Vinther, Tine N; Pettersson, Ingrid; Huus, Kasper

    2015-01-01

    The structure of insulin, a glucose homeostasis-controlling hormone, is highly conserved in all vertebrates and stabilized by three disulfide bonds. Recently, we designed a novel insulin analogue containing a fourth disulfide bond located between positions A10-B4. The N-terminus of insulin's B......-chain is flexible and can adapt multiple conformations. We examined how well disulfide bond predictions algorithms could identify disulfide bonds in this region of insulin. In order to identify stable insulin analogues with additional disulfide bonds, which could be expressed, the Cβ cut-off distance had...... in comparison to analogues with additional disulfide bonds that were more difficult to predict. In contrast, addition of the fourth disulfide bond rendered all analogues resistant to fibrillation under stress conditions and all stable analogues bound to the insulin receptor with picomolar affinities. Thus...

  19. Volumes and doses for external radiotherapy - Definitions and recommendations; Volum og doser i ekstern straaleterapi - Definisjoner og anbefalinger

    Energy Technology Data Exchange (ETDEWEB)

    Levernes, Sverre (ed.)

    2012-07-01

    The report contains definitions of volume and dose parameters for external radiotherapy. In addition the report contains recommendations for use, documentation and minimum reporting for radiotherapy of the individual patient.(Author)

  20. http://www.phrp.com.au/issues/february-2017-volume-27-issue-1-2/dynamic-simulation-modelling-of-policy-responses-to-reduce-alcohol-related-harms-rationale-and-procedure-for-a-participatory-approach/

    Directory of Open Access Journals (Sweden)

    Jo-An Atkinson

    2017-02-01

    Full Text Available Development of effective policy responses to address complex public health problems can be challenged by a lack of clarity about the interaction of risk factors driving the problem, differing views of stakeholders on the most appropriate and effective intervention approaches, a lack of evidence to support commonly implemented and acceptable intervention approaches, and a lack of acceptance of effective interventions. Consequently, political considerations, community advocacy and industry lobbying can contribute to a hotly contested debate about the most appropriate course of action; this can hinder consensus and give rise to policy resistance. The problem of alcohol misuse and its associated harms in New South Wales (NSW, Australia, provides a relevant example of such challenges. Dynamic simulation modelling is increasingly being valued by the health sector as a robust tool to support decision making to address complex problems. It allows policy makers to ask ‘what-if’ questions and test the potential impacts of different policy scenarios over time, before solutions are implemented in the real world. Participatory approaches to modelling enable researchers, policy makers, program planners, practitioners and consumer representatives to collaborate with expert modellers to ensure that models are transparent, incorporate diverse evidence and perspectives, are better aligned to the decision-support needs of policy makers, and can facilitate consensus building for action. This paper outlines a procedure for embedding stakeholder engagement and consensus building in the development of dynamic simulation models that can guide the development of effective, coordinated and acceptable policy responses to complex public health problems, such as alcohol-related harms in NSW.

  1. Correlation of Magnetic Resonance Imaging Tumor Volume with Histopathology

    Science.gov (United States)

    Turkbey, Baris; Mani, Haresh; Aras, Omer; Rastinehad, Ardeshir R.; Shah, Vijay; Bernardo, Marcelino; Pohida, Thomas; Daar, Dagane; Benjamin, Compton; McKinney, Yolanda L.; Linehan, W. Marston; Wood, Bradford J.; Merino, Maria J.; Choyke, Peter L.; Pinto, Peter A.

    2017-01-01

    Purpose The biology of prostate cancer may be influenced by the index lesion. The definition of index lesion volume is important for appropriate decision making, especially for image guided focal treatment. We determined the accuracy of magnetic resonance imaging for determining index tumor volume compared with volumes derived from histopathology. Materials and Methods We evaluated 135 patients (mean age 59.3 years) with a mean prostate specific antigen of 6.74 ng/dl who underwent multiparametric 3T endorectal coil magnetic resonance imaging of the prostate and subsequent radical prostatectomy. Index tumor volume was determined prospectively and independently by magnetic resonance imaging and histopathology. The ellipsoid formula was applied to determine histopathology tumor volume, whereas manual tumor segmentation was used to determine magnetic resonance tumor volume. Histopathology tumor volume was correlated with age and prostate specific antigen whereas magnetic resonance tumor volume involved Pearson correlation and linear regression methods. In addition, the predictive power of magnetic resonance tumor volume, prostate specific antigen and age for estimating histopathology tumor volume (greater than 0.5 cm3) was assessed by ROC analysis. The same analysis was also conducted for the 1.15 shrinkage factor corrected histopathology data set. Results There was a positive correlation between histopathology tumor volume and magnetic resonance tumor volume (Pearson coefficient 0.633, p <0.0001), but a weak correlation between prostate specific antigen and histopathology tumor volume (Pearson coefficient 0.237, p=0.003). On linear regression analysis histopathology tumor volume and magnetic resonance tumor volume were correlated (r2=0.401, p <0.00001). On ROC analysis AUC values for magnetic resonance tumor volume, prostate specific antigen and age in estimating tumors larger than 0.5 cm3 at histopathology were 0.949 (p <0.0000001), 0.685 (p=0.001) and 0.627 (p=0

  2. Monitoring and control requirement definition study for dispersed storage and generation (DSG). Volume IV. Final report, Appendix C: identification from utility visits of present and future approaches to integration of DSG into distribution networks

    Energy Technology Data Exchange (ETDEWEB)

    1980-10-01

    A major aim of the US National Energy Policy, as well as that of the New York State Energy Research and Development Authority, is to conserve energy and to shift from oil to more abundant domestic fuels and renewable energy sources. Dispersed Storage and Generation (DSG) is the term that characterizes the present and future dispersed, relatively small (<30 MW) energy systems, such as solar thermal electric, photovoltaic, wind, fuel cell, storage battery, hydro, and cogeneration, which can help achieve these national energy goals and can be dispersed throughout the distribution portion of an electric utility system. As a result of visits to four utilities concerned with the use of DSG power sources on their distribution networks, some useful impressions of present and future approaches to the integration of DSGs into electrical distribution network have been obtained. A more extensive communications and control network will be developed by utilities for control of such sources for future use. Different approaches to future utility systems with DSG are beginning to take shape. The new DSG sources will be in decentralized locations with some measure of centralized control. The utilities have yet to establish firmly the communication and control means or their organization. For the present, the means for integrating the DSGs and their associated monitoring and control equipment into a unified system have not been decided.

  3. Postoperative volume balance

    DEFF Research Database (Denmark)

    Frost, H; Mortensen, C.R.; Secher, Niels H.

    2017-01-01

    In healthy humans, stroke volume (SV) and cardiac output (CO) do not increase with expansion of the central blood volume by head-down tilt or administration of fluid. Here, we exposed 85 patients to Trendelenburg's position about one hour after surgery while cardiovascular variables were determined...... non-invasively by Modelflow. In Trendelenburg's position, SV (83 ± 19 versus 89 ± 20 ml) and CO (6·2 ± 1·8 versus 6·8 ± 1·8 l/min; both Pheart rate (75 ± 15 versus 76 ± 14 b min(-1) ) and mean arterial pressure were unaffected (84 ± 15 versus 84 ± 16 mmHg). For the 33 patients......, determination of SV and/or CO in Trendelenburg's position can be used to evaluate whether a patient is in need of IV fluid as here exemplified after surgery....

  4. The selective addition of water

    NARCIS (Netherlands)

    Resch, V.; Hanefeld, U.

    2014-01-01

    Water is omnipresent and essential. Yet at the same time it is a rather unreactive molecule. The direct addition of water to C[double bond, length as m-dash]C double bonds is therefore a challenge not answered convincingly. In this perspective we critically evaluate the selectivity and the applicabi

  5. Pragmatics in Court Interpreting: Additions

    DEFF Research Database (Denmark)

    Jacobsen, Bente

    2003-01-01

    Danish court interpreters are expected to follow ethical guidelines, which instruct them to deliver exact verbatim versions of source texts. However, this requirement often clashes with the reality of the interpreting situation in the courtroom. This paper presents and discusses the findings of a...... of an investigation regarding one kind of interpreter modification in particular: additions. The investigation was undertaken for a doctoral thesis....

  6. Additively manufactured porous tantalum implants

    NARCIS (Netherlands)

    Wauthle, Ruben; Van Der Stok, Johan; Yavari, Saber Amin; Van Humbeeck, Jan; Kruth, Jean Pierre; Zadpoor, Amir Abbas; Weinans, Harrie; Mulier, Michiel; Schrooten, Jan

    2015-01-01

    The medical device industry's interest in open porous, metallic biomaterials has increased in response to additive manufacturing techniques enabling the production of complex shapes that cannot be produced with conventional techniques. Tantalum is an important metal for medical devices because of it

  7. Select Papers. Volume 1

    Science.gov (United States)

    2011-08-01

    non- uniform rational B-splines (NURBS), 127 and BRL-CAD TM format. This dual-package development allowed for rapid development of components ...next generation of scientists and engineers. A fundamental component of our outreach program is to provide students research experiences at ARL...summer intern. There, I ran Volume Based Morphometry , an application of Statistical Parametric Mapping that was new to the Hirsch lab. I

  8. Oil additive and its effect

    Directory of Open Access Journals (Sweden)

    Vojtěch Kumbár

    2013-01-01

    Full Text Available The aim of this paper are experimental approaches, selected for analysis of the engine oils and described above, are surely sufficient for the needs of presented research. The spectrometry was used for determination of presence of selected chemical elements and especially metals in oil. Particles monitoring was employed in order to describe the amount, type, and size of friction particles. The temperature dependence of dynamic viscosity was evaluated by use of rotary viscometer. In case of all three approaches it is advantageous to compare the measured values with the results received for unused engine oil of the same marking and viscosity index. If the degradation of oil is classified as low or medium, it is possible to increase its service life for several thousands of kilometers. Mathematical model (polynomial 6th degree it was used for fitting experimental values.

  9. Gray and white matter volume abnormalities in generalized anxiety disorder by categorical and dimensional characterization.

    Science.gov (United States)

    Hilbert, Kevin; Pine, Daniel S; Muehlhan, Markus; Lueken, Ulrike; Steudte-Schmiedgen, Susann; Beesdo-Baum, Katja

    2015-12-30

    Increasing efforts have been made to investigate the underlying pathophysiology of generalized anxiety disorder (GAD), but only limited consistent information is available on gray (GM) and white matter (WM) volume changes in affected adults. Additionally, few studies employed dimensional approaches to GAD pathology. This study compares structural brain imaging data from n=19 GAD subjects and n=24 healthy comparison (HC) subjects, all medication-free and matched on age, sex and education. Separate categorical and dimensional models were employed using voxel-based morphometry for GM and WM. Significantly higher GM volumes were found in GAD subjects mainly in basal ganglia structures and less consistently in the superior temporal pole. For WM, GAD subjects showed significantly lower volumes in the dlPFC. Largely consistent findings in dimensional and categorical models point toward these structural alterations being reliable and of importance for GAD. While lower volume in the dlPFC could reflect impaired emotional processing and control over worry in GAD, basal ganglia alterations may be linked to disturbed gain and loss anticipation as implicated in previous functional GAD studies. As perturbations in anticipation processes are central to GAD, these areas may warrant greater attention in future studies.

  10. Photoexcitation of volume plasmons in metallic nanostructures

    Energy Technology Data Exchange (ETDEWEB)

    Ehrhold, Katja; Goesele, Ulrich [Max-Planck-Institut, Weinberg 2, 06120 Halle (Germany); Christiansen, Silke [Institut fuer Photonische Technologien, Albert-Einstein-Str. 9, 07745 Jena (Germany); Max-Planck-Institut, Weinberg 2, 06120 Halle (Germany)

    2009-07-01

    It has long been known that a vanishing permittivity enables longitudinal electromagnetic waves. The corresponding collective eigenmodes called volume plasmons should not be dipole excitable in classical electrodynamics. Thus, the typical volume modes are known to be excitable via particle beams solely. We investigated typical scattering problems for an incident plane wave determined via the Helmholtz-equation which can be solved analytically for special geometries. The analytical solution for a spherical scatterer by Gustav Mie was extended to spherical core-shell structures by Aden. Remarkably, in the case of metallic nanoshell structures the Mie extinction efficiencies have a local maximum at the natural plasma frequency corresponding to the photoexcitation of a volume plasmon. This volume mode is independent of both the shell's aspect ratio and the core material. For explanation we present a simple physical picture which is supported by analytical examples on silver and gold shells. Additionally we use finite element simulations to show a potpourri of particles which likewise enable the photoexcitation of volume modes.

  11. Additive manufacturing technology in reconstructive surgery.

    Science.gov (United States)

    Fuller, Scott C; Moore, Michael G

    2016-10-01

    Technological advances have been part and parcel of modern reconstructive surgery, in that practitioners of this discipline are continually looking for innovative ways to perfect their craft and improve patient outcomes. We are currently in a technological climate wherein advances in computers, imaging, and science have coalesced with resulting innovative breakthroughs that are not merely limited to improved outcomes and enhanced patient care, but may provide novel approaches to training the next generation of reconstructive surgeons. New developments in software and modeling platforms, imaging modalities, tissue engineering, additive manufacturing, and customization of implants are poised to revolutionize the field of reconstructive surgery. The interface between technological advances and reconstructive surgery continues to expand. Additive manufacturing techniques continue to evolve in an effort to improve patient outcomes, decrease operative time, and serve as instructional tools for the training of reconstructive surgeons.

  12. An Additive Definition of Molecular Complexity.

    Science.gov (United States)

    Böttcher, Thomas

    2016-03-28

    A framework for molecular complexity is established that is based on information theory and consistent with chemical knowledge. The resulting complexity index Cm is derived from abstracting the information content of a molecule by the degrees of freedom in the microenvironments on a per-atom basis, allowing the molecular complexity to be calculated in a simple and additive way. This index allows the complexity of any molecule to be universally assessed and is sensitive to stereochemistry, heteroatoms, and symmetry. The performance of this complexity index is evaluated and compared against the current state of the art. Its additive character gives consistent values also for very large molecules and supports direct comparisons of chemical reactions. Finally, this approach may provide a useful tool for medicinal chemistry in drug design and lead selection, as demonstrated by correlating molecular complexities of antibiotics with compound-specific parameters.

  13. Additive manufacturing of polymer-derived ceramics

    Science.gov (United States)

    Eckel, Zak C.; Zhou, Chaoyin; Martin, John H.; Jacobsen, Alan J.; Carter, William B.; Schaedler, Tobias A.

    2016-01-01

    The extremely high melting point of many ceramics adds challenges to additive manufacturing as compared with metals and polymers. Because ceramics cannot be cast or machined easily, three-dimensional (3D) printing enables a big leap in geometrical flexibility. We report preceramic monomers that are cured with ultraviolet light in a stereolithography 3D printer or through a patterned mask, forming 3D polymer structures that can have complex shape and cellular architecture. These polymer structures can be pyrolyzed to a ceramic with uniform shrinkage and virtually no porosity. Silicon oxycarbide microlattice and honeycomb cellular materials fabricated with this approach exhibit higher strength than ceramic foams of similar density. Additive manufacturing of such materials is of interest for propulsion components, thermal protection systems, porous burners, microelectromechanical systems, and electronic device packaging.

  14. Additive manufacturing of polymer-derived ceramics.

    Science.gov (United States)

    Eckel, Zak C; Zhou, Chaoyin; Martin, John H; Jacobsen, Alan J; Carter, William B; Schaedler, Tobias A

    2016-01-01

    The extremely high melting point of many ceramics adds challenges to additive manufacturing as compared with metals and polymers. Because ceramics cannot be cast or machined easily, three-dimensional (3D) printing enables a big leap in geometrical flexibility. We report preceramic monomers that are cured with ultraviolet light in a stereolithography 3D printer or through a patterned mask, forming 3D polymer structures that can have complex shape and cellular architecture. These polymer structures can be pyrolyzed to a ceramic with uniform shrinkage and virtually no porosity. Silicon oxycarbide microlattice and honeycomb cellular materials fabricated with this approach exhibit higher strength than ceramic foams of similar density. Additive manufacturing of such materials is of interest for propulsion components, thermal protection systems, porous burners, microelectromechanical systems, and electronic device packaging.

  15. Small-Volume Injections: Evaluation of Volume Administration Deviation From Intended Injection Volumes.

    Science.gov (United States)

    Muffly, Matthew K; Chen, Michael I; Claure, Rebecca E; Drover, David R; Efron, Bradley; Fitch, William L; Hammer, Gregory B

    2017-10-01

    In the perioperative period, anesthesiologists and postanesthesia care unit (PACU) nurses routinely prepare and administer small-volume IV injections, yet the accuracy of delivered medication volumes in this setting has not been described. In this ex vivo study, we sought to characterize the degree to which small-volume injections (≤0.5 mL) deviated from the intended injection volumes among a group of pediatric anesthesiologists and pediatric postanesthesia care unit (PACU) nurses. We hypothesized that as the intended injection volumes decreased, the deviation from those intended injection volumes would increase. Ten attending pediatric anesthesiologists and 10 pediatric PACU nurses each performed a series of 10 injections into a simulated patient IV setup. Practitioners used separate 1-mL tuberculin syringes with removable 18-gauge needles (Becton-Dickinson & Company, Franklin Lakes, NJ) to aspirate 5 different volumes (0.025, 0.05, 0.1, 0.25, and 0.5 mL) of 0.25 mM Lucifer Yellow (LY) fluorescent dye constituted in saline (Sigma Aldrich, St. Louis, MO) from a rubber-stoppered vial. Each participant then injected the specified volume of LY fluorescent dye via a 3-way stopcock into IV tubing with free-flowing 0.9% sodium chloride (10 mL/min). The injected volume of LY fluorescent dye and 0.9% sodium chloride then drained into a collection vial for laboratory analysis. Microplate fluorescence wavelength detection (Infinite M1000; Tecan, Mannedorf, Switzerland) was used to measure the fluorescence of the collected fluid. Administered injection volumes were calculated based on the fluorescence of the collected fluid using a calibration curve of known LY volumes and associated fluorescence.To determine whether deviation of the administered volumes from the intended injection volumes increased at lower injection volumes, we compared the proportional injection volume error (loge [administered volume/intended volume]) for each of the 5 injection volumes using a linear

  16. Uncertainty-aware guided volume segmentation.

    Science.gov (United States)

    Prassni, Jörg-Stefan; Ropinski, Timo; Hinrichs, Klaus

    2010-01-01

    Although direct volume rendering is established as a powerful tool for the visualization of volumetric data, efficient and reliable feature detection is still an open topic. Usually, a tradeoff between fast but imprecise classification schemes and accurate but time-consuming segmentation techniques has to be made. Furthermore, the issue of uncertainty introduced with the feature detection process is completely neglected by the majority of existing approaches.In this paper we propose a guided probabilistic volume segmentation approach that focuses on the minimization of uncertainty. In an iterative process, our system continuously assesses uncertainty of a random walker-based segmentation in order to detect regions with high ambiguity, to which the user's attention is directed to support the correction of potential misclassifications. This reduces the risk of critical segmentation errors and ensures that information about the segmentation's reliability is conveyed to the user in a dependable way. In order to improve the efficiency of the segmentation process, our technique does not only take into account the volume data to be segmented, but also enables the user to incorporate classification information. An interactive workflow has been achieved by implementing the presented system on the GPU using the OpenCL API. Our results obtained for several medical data sets of different modalities, including brain MRI and abdominal CT, demonstrate the reliability and efficiency of our approach.

  17. [Information about phosphorus additives and nutritional counseling].

    Science.gov (United States)

    Kido, Shinsuke; Nomura, Kengo; Sasaki, Shohei; Shiozaki, Yuji; Segawa, Hiroko; Tatsumi, Sawako

    2012-10-01

    Hyperphosphatemia is a common disorder in patients with chronic kidney disease (CKD) , and may result in hyperparathyroidism and renal osteodystrophy. Hyperphosphatemia also may contribute to deterioration vascular calcification and increase mortality. Hence, correction and prevention of hyperphosphatemia is a main component of the management of CKD. This goal is usually approached both by administering phosphorus binders and by restricting dietary phosphorus (P) intake. Dietary intake of phosphorus (P) is derived largely from foods with high protein content or food additives and is an important determinant of P balance in patient with CKD. Food additives (PO4) can dramatically increase the amount of P consumed in the daily diet, especially because P is more readily absorbed in its inorganic form. In addition, information about the P content and type in prepared foods is often unavailable or misleading. Therefore, during dietary counseling of patients with CKD, we recommended that they consider both the absolute dietary P content and the P-to-protein ratio of foods and meals including food additives.

  18. Biofuels and the need for additional carbon

    Energy Technology Data Exchange (ETDEWEB)

    Searchinger, Timothy D, E-mail: tsearchi@princeton.edu [Princeton Environmental Institute and Woodrow Wilson School, Princeton University, M27 Guyot Hall, Princeton, NJ 08544 (United States); Transatlantic Fellow of the German Marshall Fund of the US, 1744 R Street, NW, Washington, DC 20009 (United States)

    2010-04-15

    Use of biofuels does not reduce emissions from energy combustion but may offset emissions by increasing plant growth or by reducing plant residue or other non-energy emissions. To do so, biofuel production must generate and use 'additional carbon', which means carbon that plants would not otherwise absorb or that would be emitted to the atmosphere anyway. When biofuels cause no direct land use change, they use crops that would grow regardless of biofuels so they do not directly absorb additional carbon. All potential greenhouse gas reductions from such biofuels, as well as many potential emission increases, result from indirect effects, including reduced crop consumption, price-induced yield gains and land conversion. If lifecycle analyses ignore indirect effects of biofuels, they therefore cannot properly find greenhouse gas reductions. Uncertainties in estimating indirect emission reductions and increases are largely symmetrical. The failure to distinguish 'additional' carbon from carbon already absorbed or withheld from the atmosphere also leads to large overestimates of global bioenergy potential. Reasonable confidence in greenhouse gas reductions requires a precautionary approach to estimating indirect effects that does not rely on any single model. Reductions can be more directly assured, and other adverse indirect effects avoided, by focusing on biofuels from directly additional carbon.

  19. Additionality of global benefits and financial additionality in the context of the AIJ negotiations

    Energy Technology Data Exchange (ETDEWEB)

    Puhl, I.

    1996-12-31

    The Conference of the Party at their first meeting (COP1) took a decision regarding criteria for joint implementation as indicated in Art. 4.2 (a) of the FCCC which established a pilot phase for activities implemented jointly (AIJ) under the pilot phase. Besides some more technical issues this decision specified that such measures should bring about real, measurable and long-term environmental benefits related to the mitigation of climate change that would not have occurred in the absence of such activities. It also established that the financing of AIJ shall be additional to the financial obligations of developed country parties. These two requirements are called the additionality criteria for AIJ. The first refers to the realness of GHG emission abatement (which means reduction compared to a baseline) whereas the second describes that funds earmarked for AIJ have no other objective (i.e. profit making, export promotion) but to reduce GHG emissions to avoid the free-riding of investors and subsequently developed country parties. The reporting framework as well as the reporting requirements under national programs do not specify further the two types of additionality and even though research focuses on issues like baseline determination there has been no attempt so far to identify approaches which contribute towards defining strict and practicable methods and guidelines to frame additionality criteria. The first FCCC assessment of pilot project reporting revealed that in the reporting of activities, emissions additionality often remained unclear, especially in cases where AIJ was only a portion of an existing or already planned project, and that there is a point about how to account for financial additionality. It subsequently proposed to develop a uniform approach to baseline determination and the assessment of emission (reduction) additionality and financial additionality.

  20. Improvements in floating point addition/subtraction operations

    Energy Technology Data Exchange (ETDEWEB)

    Farmwald, P.M.

    1984-02-24

    Apparatus is described for decreasing the latency time associated with floating point addition and subtraction in a computer, using a novel bifurcated, pre-normalization/post-normalization approach that distinguishes between differences of floating point exponents.

  1. Cohomology of exact categories and (non-)additive sheaves

    CERN Document Server

    Kaledin, Dmitry

    2011-01-01

    We use (non-)additive sheaves to introduce an (absolute) notion of Hochschild cohomology for exact categories as Ext's in a suitable bisheaf category. We compare our approach to various definitions present in the literature.

  2. Protocol for ADDITION-PRO

    DEFF Research Database (Denmark)

    Johansen, Nanna Borup; Hansen, Anne-Louise Smidt; Jensen, Troels M

    2012-01-01

    disease and microvascular diabetic complications. We also require a better understanding of the mechanisms that underlie and drive early changes in cardiometabolic physiology. The ADDITION-PRO study was designed to address these issues among individuals at different levels of diabetes risk recruited from...... Danish primary care. METHODS/DESIGN: ADDITION-PRO is a population-based, longitudinal cohort study of individuals at high risk for diabetes. 16,136 eligible individuals were identified at high risk following participation in a stepwise screening programme in Danish general practice between 2001 and 2006...... at high risk for diabetes. The detailed phenotyping of this cohort will also allow a number of research questions concerning early changes in cardiometabolic physiology to be addressed....

  3. The Frontiers of Additive Manufacturing

    Energy Technology Data Exchange (ETDEWEB)

    Grote, Christopher John [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2016-03-03

    Additive manufacturing, more commonly known as 3-D printing, has become a ubiquitous tool in science for its precise control over mechanical design. For additive manufacturing to work, a 3-D structure is split into thin 2D slices, and then different physical properties, such as photo-polymerization or melting, are used to grow the sequential layers. The level of control allows not only for devices to be made with a variety of materials: e.g. plastics, metals, and quantum dots, but to also have finely controlled structures leading to other novel properties. While 3-D printing is widely used by hobbyists for making models, it also has industrial applications in structural engineering, biological tissue scaffolding, customized electric circuitry, fuel cells, security, and more.

  4. Ice cream with additional value

    OpenAIRE

    Melicharová, Barbora

    2016-01-01

    The aim of this bachelor thesis is to summarise current knowledge about production and properties of ice cream with an additional value. Nowadays, incorporation of probiotics is considered as the most intensively studied possibility for functional ice cream manufacture. Their viability depends on the kind of a microorganism, for example bifidobacteria are mostly less stable than lactobacilli in ice cream matrix. Lactobacillus acidophilus AB518, AK414, Lactobacillus agilis AA1773, AC1888 and L...

  5. ADDITIONAL STREET BERBASIS APP INVENTOR

    Directory of Open Access Journals (Sweden)

    Mohammad Adib Adhi Prabowo

    2013-05-01

    Full Text Available Abstrak Seiring dengan perkembangan sistem operasi android, telah banyak aplikasi yang memanfaatkan fasilitas GPS dan Google Map, seperti untuk mencari rute, mendapatkan peta, mencari lokasi tertentu pada sebuah tempat. Akan tetapi seringkali pengguna perangkat bergerak kesulitan ketika ingin mengetahui beberapa tempat dan lokasi tertentu karena belum ada fasilitas yang menyediakan informasi lokasi suatu tempat. Walaupun ada informasi lokasi pada peta biasanya informasi yang diberikan lokasi tempat berskala besar, misalnya lokasi tempat wisata atau stasiun kereta api. Pengembangan aplikasi untuk skala kecil ini akan memberikan informasi yang dipresentasikan pada google map. Selama ini belum ada yang memberikan sebuah informasi lokasi tempat penting yang berskala kecil. Misalnya informasi lokasi  tambal ban, lokasi warung makan, lokasi laundry, dan lokasi bengkel motor. Oleh karena itu kami mencoba untuk mengembangkan aplikasi additional street berbasis android via App Inventor dengan bantuan google maps. Aplikasi additional street ini dapat memberikan informasi letak objek pada peta serta memberikan informasi jalan menuju lokasi tersebut dan detail informasi lokasi tersebut serta lokasi dari pengguna aplikasi tersebut. Kata Kunci: additional street, android, google maps, app inventor, GPS

  6. Reversible Oxidative Addition at Carbon.

    Science.gov (United States)

    Eichhorn, Antonius F; Fuchs, Sonja; Flock, Marco; Marder, Todd B; Radius, Udo

    2017-04-07

    The reactivity of N-heterocyclic carbenes (NHCs) and cyclic alkyl amino carbenes (cAACs) with arylboronate esters is reported. The reaction with NHCs leads to the reversible formation of thermally stable Lewis acid/base adducts Ar-B(OR)2 ⋅NHC (Add1-Add6). Addition of cAAC(Me) to the catecholboronate esters 4-R-C6 H4 -Bcat (R=Me, OMe) also afforded the adducts 4-R-C6 H4 Bcat⋅cAAC(Me) (Add7, R=Me and Add8, R=OMe), which react further at room temperature to give the cAAC(Me) ring-expanded products RER1 and RER2. The boronate esters Ar-B(OR)2 of pinacol, neopentylglycol, and ethyleneglycol react with cAAC at RT via reversible B-C oxidative addition to the carbene carbon atom to afford cAAC(Me) (B{OR}2 )(Ar) (BCA1-BCA6). NMR studies of cAAC(Me) (Bneop)(4-Me-C6 H4 ) (BCA4) demonstrate the reversible nature of this oxidative addition process.

  7. Environmental Report 1996, Volume 2

    Energy Technology Data Exchange (ETDEWEB)

    Harrach, R.J.

    1996-01-01

    This is Volume 2 of the Lawrence Livermore National Laboratory`s (LLNL`s) annual Environmental Report 1996, prepared for the US Department of Energy. Volume 2 supports Volume 1 summary data and is essentially a detailed data report that provides individual data points, where applicable. Volume 2 includes information on monitoring of air, air effluents, sewerable water, surface water, ground water, soil and sediment, vegetation and foodstuff, environmental radiation, and quality assurance.

  8. A perturbative approach to Lagrangian flow networks

    CERN Document Server

    Fujiwara, Naoya; Donges, Jonathan F; Donner, Reik V

    2016-01-01

    Complex network approaches have been successfully applied for studying transport processes in complex systems ranging from road, railway or airline infrastructure over industrial manufacturing to fluid dynamics. Here, we utilize a generic framework for describing the dynamics of geophysical flows such as ocean currents or atmospheric wind fields in terms of Lagrangian flow networks. In this approach, information on the passive advection of particles is transformed into a Markov chain based on transition probabilities of particles between the volume elements of a given partition of space for a fixed time step. We employ perturbation-theoretic methods to investigate the effects of modifications of transport processes in the underlying flow for three different problem classes: efficient absorption (corresponding to particle trapping or leaking), constant input of particles (with additional source terms modeling, e.g., localized contamination), and shifts of the steady state under probability mass conservation (a...

  9. Evaluation of certain food additives.

    Science.gov (United States)

    2009-01-01

    This report represents the conclusions of a Joint FAO/WHO Expert Committee convened to evaluate the safety of various food additives, including flavouring agents, with a view to recommending acceptable daily intakes (ADIs) and to preparing specifications for identity and purity. The first part of the report contains a general discussion of the principles governing the toxicological evaluation and assessment of intake of food additives (in particular, flavouring agents). A summary follows of the Committee's evaluations of technical, toxicological and intake data for certain food additives (asparaginase from Aspergillus niger expressed in A. niger, calcium lignosulfonate (40-65), ethyl lauroyl arginate, paprika extract, phospholipase C expressed in Pichia pastoris, phytosterols, phytostanols and their esters, polydimethylsiloxane, steviol glycosides and sulfites [assessment of dietary exposure]) and 10 groups of related flavouring agents (aliphatic branched-chain saturated and unsaturated alcohols, aldehydes, acids and related esters; aliphatic linear alpha,beta-unsaturated aldehydes, acids and related alcohols, acetals and esters; aliphatic secondary alcohols, ketones and related esters; alkoxy-substituted allylbenzenes present in foods and essential oils and used as flavouring agents; esters of aliphatic acyclic primary alcohols with aliphatic linear saturated carboxylic acids; furan-substituted aliphatic hydrocarbons, alcohols, aldehydes, ketones, carboxylic acids and related esters, sulfides, disulfides and ethers; miscellaneous nitrogen-containing substances; monocyclic and bicyclic secondary alcohols, ketones and related esters; hydroxy- and alkoxy-substituted benzyl derivatives; and substances structurally related to menthol). Specifications for the following food additives were revised: canthaxanthin; carob bean gum and carob bean gum (clarified); chlorophyllin copper complexes, sodium and potassium salts; Fast Green FCF; guar gum and guar gum (clarified

  10. Fire-Retardant Polymeric Additives

    Science.gov (United States)

    Williams, Martha K.; Smith, Trent M.

    2011-01-01

    Polyhydroxyamide (PHA) and polymethoxyamide (PMeOA) are fire-retardant (FR) thermoplastic polymers and have been found to be useful as an additive for imparting fire retardant properties to other compatible, thermoplastic polymers (including some elastomers). Examples of compatible flammable polymers include nylons, polyesters, and acrylics. Unlike most prior additives, PHA and PMeOA do not appreciably degrade the mechanical properties of the matrix polymer; indeed, in some cases, mechanical properties are enhanced. Also, unlike some prior additives, PHA and PMeOA do not decompose into large amounts of corrosive or toxic compounds during combustion and can be processed at elevated temperatures. PMeOA derivative formulations were synthesized and used as an FR additive in the fabrication of polyamide (PA) and polystyrene (PS) composites with notable reduction (>30 percent for PS) in peak heat release rates compared to the neat polymer as measured by a Cone Calorimeter (ASTM E1354). Synergistic effects were noted with nanosilica composites. These nanosilica composites had more than 50-percent reduction in peak heat release rates. In a typical application, a flammable thermoplastic, thermoplastic blend, or elastomer that one seeks to render flame-retardant is first dry-mixed with PHA or PMeOA or derivative thereof. The proportion of PHA or PMeOA or derivative in the mixture is typically chosen to lie between 1 and 20 weight percent. The dry blend can then be melt-extruded. The extruded polymer blend can further be extruded and/or molded into fibers, pipes, or any other of a variety of objects that may be required to be fire-retardant. The physical and chemical mechanisms which impart flame retardancy of the additive include inhibiting free-radical oxidation in the vapor phase, preventing vaporization of fuel (the polymer), and cooling through the formation of chemical bonds in either the vapor or the condensed phase. Under thermal stress, the cyclic hydroxyl/ methoxy

  11. REFLECTION AND REFRACTION, VOLUME 2.

    Science.gov (United States)

    KLAUS, DAVID J.; AND OTHERS

    THIS VOLUME 2 OF A TWO-VOLUME SET PROVIDES AUTOINSTRUCTION IN PHYSICS. THE UNITS COVERED IN THIS VOLUME ARE (1) REFLECTION OF LIGHT, (2) PHOTOMETRY, (3) POLARIZATION, (4) REFRACTION OF LIGHT, (5) SNELL'S LAW, (6) LENSES, FOCUS, AND FOCAL POINTS, (7) IMAGE FORMATION, AND (8) ABERRATIONS, THE EYE, AND MAGNIFICATION. THE INTRODUCTION AND UNITS ON…

  12. Calculus Students' Understanding of Volume

    Science.gov (United States)

    Dorko, Allison; Speer, Natasha M.

    2013-01-01

    Researchers have documented difficulties that elementary school students have in understanding volume. Despite its importance in higher mathematics, we know little about college students' understanding of volume. This study investigated calculus students' understanding of volume. Clinical interview transcripts and written responses to volume…

  13. Additive Manufacturing of Dense Hexagonal Boron Nitride Objects

    Energy Technology Data Exchange (ETDEWEB)

    Marquez Rossy, Andres E [ORNL; Armstrong, Beth L [ORNL; Elliott, Amy M [ORNL; Lara-Curzio, Edgar [ORNL

    2017-05-12

    The feasibility of manufacturing hexagonal boron nitride objects via additive manufacturing techniques was investigated. It was demonstrated that it is possible to hot-extrude thermoplastic filaments containing uniformly distributed boron nitride particles with a volume concentration as high as 60% and that these thermoplastic filaments can be used as feedstock for 3D-printing objects using a fused deposition system. Objects 3D-printed by fused deposition were subsequently sintered at high temperature to obtain dense ceramic products. In a parallel study the behavior of hexagonal boron nitride in aqueous solutions was investigated. It was shown that the addition of a cationic dispersant to an azeotrope enabled the formulation of slurries with a volume concentration of boron nitride as high as 33%. Although these slurries exhibited complex rheological behavior, the results from this study are encouraging and provide a pathway for manufacturing hexagonal boron nitride objects via robocasting.

  14. Investigations of non-linear polymers as high performance lubricant additives

    Energy Technology Data Exchange (ETDEWEB)

    Robinson, Joshua W.; Bhattacharya, Priyanka; Qu, Jun; Bays, J. Timothy; Cosimbescu, Lelia

    2015-03-22

    Off-the-shelf available engine oils contain an assortment of additives that increase the performance of base oils and maximize the overall efficiency of the machine. With ever increasing requirements for fuel efficiency, the demand for novel materials that outperform older generations is also on the rise. One approach towards increasing overall efficiency is to reduce internal friction and wear in an engine. From an additive approach, this is typically achieved by altering the bulk oil’s viscosity at high temperatures via polymers. In general, the hydrodynamic volume of polymers increase (expand) at elevated temperatures and decrease (contract/deflate) with declining temperatures and this effect is enhanced be carefully designing specific structures and architectures. The natural thinning tendency of base oil with increasing temperatures is in part mitigated by the expansion of the macromolecules added, and the overall effect is decreasing the viscosity losses at high temperatures. Traditional polymer architectures vary from linear to dendritic, where linear polymers of the same chemical composition and molecular weight to its dendritic counterpart will undergo a more significant free volume change in solution with regards to temperature changes. This advantage has been exploited in the literature towards the production of viscosity modifiers. However, one major disadvantage of linear polymers is degradation due to mechanical shear forces and high temperatures causing a shorter additive lifetime. Dendrimers on the other hand are known to demonstrate superior robustness to shear degradation when compared to their respective linear counterparts. An additional advantage of the dendritic architecture is the ability to tailor the peripheral end-groups towards influencing polymer-solvent and/or polymer-surface interactions. Comb-burst hyperbranched polymers are a hybrid of the aforementioned architectures and provide several compromises between the traditional

  15. Finite-volume cumulant expansion in QCD-colorless plasma

    Energy Technology Data Exchange (ETDEWEB)

    Ladrem, M. [Taibah University, Physics Department, Faculty of Science, Al-Madinah, Al-Munawwarah (Saudi Arabia); Physics Department, Algiers (Algeria); ENS-Vieux Kouba (Bachir El-Ibrahimi), Laboratoire de Physique et de Mathematiques Appliquees (LPMA), Algiers (Algeria); Ahmed, M.A.A. [Taibah University, Physics Department, Faculty of Science, Al-Madinah, Al-Munawwarah (Saudi Arabia); ENS-Vieux Kouba (Bachir El-Ibrahimi), Laboratoire de Physique et de Mathematiques Appliquees (LPMA), Algiers (Algeria); Taiz University in Turba, Physics Department, Taiz (Yemen); Alfull, Z.Z. [Taibah University, Physics Department, Faculty of Science, Al-Madinah, Al-Munawwarah (Saudi Arabia); Cherif, S. [ENS-Vieux Kouba (Bachir El-Ibrahimi), Laboratoire de Physique et de Mathematiques Appliquees (LPMA), Algiers (Algeria); Ghardaia University, Sciences and Technologies Department, Ghardaia (Algeria)

    2015-09-15

    Due to the finite-size effects, the localization of the phase transition in finite systems and the determination of its order, become an extremely difficult task, even in the simplest known cases. In order to identify and locate the finite-volume transition point T{sub 0}(V) of the QCD deconfinement phase transition to a colorless QGP, we have developed a new approach using the finite-size cumulant expansion of the order parameter and the L{sub mn}-method. The first six cumulants C{sub 1,2,3,4,5,6} with the corresponding under-normalized ratios (skewness Σ, kurtosis κ, pentosis Π{sub ±}, and hexosis H{sub 1,2,3}) and three unnormalized combinations of them, (O = σ{sup 2}κΣ{sup -1},U = σ{sup -2}Σ{sup -1},N = σ{sup 2}κ) are calculated and studied as functions of (T, V). A new approach, unifying in a clear and consistent way the definitions of cumulant ratios, is proposed.Anumerical FSS analysis of the obtained results has allowed us to locate accurately the finite-volume transition point. The extracted transition temperature value T{sub 0}(V) agrees with that expected T{sub 0}{sup N}(V) from the order parameter and the thermal susceptibility χ{sub T} (T, V), according to the standard procedure of localization to within about 2%. In addition to this, a very good correlation factor is obtained proving the validity of our cumulants method. The agreement of our results with those obtained by means of other models is remarkable. (orig.)

  16. NASA thesaurus. Volume 2: Access vocabulary

    Science.gov (United States)

    1988-01-01

    The access vocabulary, which is essentially a permuted index, provides access to any word or number in authorized postable and nonpostable terms. Additional entries include postable and nonpostable terms, other word entries and pseudo-multiword terms that are permutations of words that contain words within words. The access vocabulary contains almost 42,000 entries that give increased access to the hierarchies in Volume 1 - Hierarchical Listing.

  17. What makes a successful volume crime investigator?

    OpenAIRE

    2011-01-01

    This exploratory study sought to understand the role of volume crime investigators in the modern era. It attempted to gain officers` perceptions on the attributes required to be a successful at the role. In addition, the research sought to understand how modern investigators thought success should be defined and measured in relation to individual investigator performance. Chapter One explored previous research relating to police investigators and success, and identified the main research que...

  18. Optimization of additive content and their combination to improve the quality of pure barley bread

    National Research Council Canada - National Science Library

    Pojić, Milica; Dapčević Hadnađev, Tamara; Hadnađev, Miroslav; Rakita, Slađana; Torbica, Aleksandra

    2017-01-01

    ...) on breadmaking potential of barley flour by using response surface methodology. Addition of these ingredients had significant effect on specific bread volume, crust and crumb lightness, crumb texture, average cell size and crumb density...

  19. Thicknesses and volumes of glaciers in the Andes of Peru estimated with satellite data and digital terrain information

    Science.gov (United States)

    Torres, Judith; Colonia, Daniel; Haeberli, Wilfried; Giráldez, Claudia; Frey, Holger; Huggel, Christian

    2014-05-01

    The glaciers in the tropical Andes of Peru have been melting at an unprecedented rate in recent years and generally after the Little Ice Age, a cold period that lasted from the 16th to the 19th century. Knowledge of glacier thicknesses and volumes is necessary for evaluating possible future scenarios of glacier shrinkage and of water supply to the Andean populations under conditions of continued warming. Calculation of glacier volumes for 19 mountain ranges in Perú has been based on two ice- thickness modeling methods including an area-related approach with different parameterizations and a slope-dependent approach. Both methods allow for rapid treatment of regional data obtained from satellite imagery and a Digital Elevation Model, integrated into a Geographic Information System. In addition, glacier outlines were obtained from the glacier inventory compiled by the Unit of Glaciology and Water Resources (UGRH) - National Water Authority (ANA) that used satellite imagery (ASTER, SPOT and LISS III from 2003 to 2010) and topographic information acquired from the cartography of the National Geographical Institute (IGN). The volume-area scaling approach resulted in glacier volume of 35.00 km3 and a total volume of 34.39 km3 resulted from the slope-dependent thickness with a thickness approximately 30 m. Estimated results also show a loss of the total ice surface ~42% and glacier volume loss about ~38% in both methods based on the first Glacier Inventory of Peru (from aerial photographs 1962 -1970) performed by HIDRANDINA SA. The results also indicate that volume estimations are subject to large uncertainties. Field measurements of glacier thickness are scarce and locally restricted due to rugged topography, high altitude and heavy crevassing of glaciers. Possibilities of calibrating and validating the applied model approaches are therefore limited. New possibilities nevertheless come into play with slope-dependent approaches, which lead beyond area-related average

  20. Understanding the heterogeneity in volume overload and fluid distribution in decompensated heart failure is key to optimal volume management: role for blood volume quantitation.

    Science.gov (United States)

    Miller, Wayne L; Mullan, Brian P

    2014-06-01

    This study sought to quantitate total blood volume (TBV) in patients hospitalized for decompensated chronic heart failure (DCHF) and to determine the extent of volume overload, and the magnitude and distribution of blood volume and body water changes following diuretic therapy. The accurate assessment and management of volume overload in patients with DCHF remains problematic. TBV was measured by a radiolabeled-albumin dilution technique with intravascular volume, pre-to-post-diuretic therapy, evaluated at hospital admission and at discharge. Change in body weight in relation to quantitated TBV was used to determine interstitial volume contribution to total fluid loss. Twenty-six patients were prospectively evaluated. Two patients had normal TBV at admission. Twenty-four patients were hypervolemic with TBV (7.4 ± 1.6 liters) increased by +39 ± 22% (range, +9.5% to +107%) above the expected normal volume. With diuresis, TBV decreased marginally (+30 ± 16%). Body weight declined by 6.9 ± 5.2 kg, and fluid intake/fluid output was a net negative 8.4 ± 5.2 liters. Interstitial compartment fluid loss was calculated at 6.2 ± 4.0 liters, accounting for 85 ± 15% of the total fluid reduction. TBV analysis demonstrated a wide range in the extent of intravascular overload. Dismissal measurements revealed marginally reduced intravascular volume post-diuretic therapy despite large reductions in body weight. Mobilization of interstitial fluid to the intravascular compartment with diuresis accounted for this disparity. Intravascular volume, however, remained increased at dismissal. The extent, composition, and distribution of volume overload are highly variable in DCHF, and this variability needs to be taken into account in the approach to individualized therapy. TBV quantitation, particularly serial measurements, can facilitate informed volume management with respect to a goal of treating to euvolemia. Copyright © 2014 American College of Cardiology Foundation. Published